40 CFR Table B-4 to Subpart B of... - Line Voltage and Room Temperature Test Conditions

Code of Federal Regulations, 2013 CFR

2013-07-01

... Conditions B Table B-4 to Subpart B of Part 53 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Testing Performance Characteristics of Automated Methods for SO2, CO, O3, and NO2 Pt. 53, Subpt. B, Table B-4 Table B-4 to Subpart B of Part 53—Line Voltage and Room Temperature Test Conditions Test day...

40 CFR Table B-4 to Subpart B of... - Line Voltage and Room Temperature Test Conditions

Code of Federal Regulations, 2014 CFR

2014-07-01

... Conditions B Table B-4 to Subpart B of Part 53 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Testing Performance Characteristics of Automated Methods for SO2, CO, O3, and NO2 Pt. 53, Subpt. B, Table B-4 Table B-4 to Subpart B of Part 53—Line Voltage and Room Temperature Test Conditions Test day...

75 FR 80293 - Airworthiness Directives; Eurocopter France Model AS 350 B, BA, B1, B2, B3, and D, and Model...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-22

... Airworthiness Directives; Eurocopter France Model AS 350 B, BA, B1, B2, B3, and D, and Model AS355 E, F, F1, F2... identified in the Applicability section, Table 1, of the AD. As published, two part numbers shown in Table 1... corrected to read as follows: Table 1 Component Part No. (P/N) Serial No. (S/N) Main rotor servo-control...

47 CFR 2.105 - United States Table of Frequency Allocations.

Code of Federal Regulations, 2010 CFR

2010-10-01

....105 Section 2.105 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL FREQUENCY ALLOCATIONS... the non-Federal Table is administered by the Federal Communications Commission (FCC). 5 1 See 2.104(b... 305(a) of the Communications Act of 1934, as amended. See Public Law 102-538, 106 Stat. 3533 (1992). 5...

40 CFR Table 2 to Subpart II of... - Volatile Organic HAP (VOHAP) Limits for Marine Coatings

Code of Federal Regulations, 2013 CFR

2013-07-01

... for Marine Coatings 2 Table 2 to Subpart II of Part 63 Protection of Environment ENVIRONMENTAL... (Surface Coating) Pt. 63, Subpt. II, Table 2 Table 2 to Subpart II of Part 63—Volatile Organic HAP (VOHAP) Limits for Marine Coatings Coating category VOHAP limits a,b,c Grams/liter coating (minus water and...

40 CFR Table 2 to Subpart II of... - Volatile Organic HAP (VOHAP) Limits for Marine Coatings

Code of Federal Regulations, 2012 CFR

2012-07-01

... for Marine Coatings 2 Table 2 to Subpart II of Part 63 Protection of Environment ENVIRONMENTAL... (Surface Coating) Pt. 63, Subpt. II, Table 2 Table 2 to Subpart II of Part 63—Volatile Organic HAP (VOHAP) Limits for Marine Coatings Coating category VOHAP limits a,b,c Grams/liter coating (minus water and...

40 CFR Table 2 to Subpart II of... - Volatile Organic HAP (VOHAP) Limits for Marine Coatings

Code of Federal Regulations, 2014 CFR

2014-07-01

... for Marine Coatings 2 Table 2 to Subpart II of Part 63 Protection of Environment ENVIRONMENTAL... (Surface Coating) Pt. 63, Subpt. II, Table 2 Table 2 to Subpart II of Part 63—Volatile Organic HAP (VOHAP) Limits for Marine Coatings Coating category VOHAP limits a b c Grams/liter coating (minus water and...

40 CFR Table 2 to Subpart II of... - Volatile Organic HAP (VOHAP) Limits for Marine Coatings

Code of Federal Regulations, 2010 CFR

2010-07-01

... for Marine Coatings 2 Table 2 to Subpart II of Part 63 Protection of Environment ENVIRONMENTAL... (Surface Coating) Pt. 63, Subpt. II, Table 2 Table 2 to Subpart II of Part 63—Volatile Organic HAP (VOHAP) Limits for Marine Coatings Coating category VOHAP limits a,b,c Grams/liter coating (minus water and...

40 CFR Table 2 to Subpart II of... - Volatile Organic HAP (VOHAP) Limits for Marine Coatings

Code of Federal Regulations, 2011 CFR

2011-07-01

... for Marine Coatings 2 Table 2 to Subpart II of Part 63 Protection of Environment ENVIRONMENTAL... (Surface Coating) Pt. 63, Subpt. II, Table 2 Table 2 to Subpart II of Part 63—Volatile Organic HAP (VOHAP) Limits for Marine Coatings Coating category VOHAP limits a,b,c Grams/liter coating (minus water and...

40 CFR Table 4 to Subpart Dd of... - Tank Control Levels for Tanks at New Affected Sources as Required by 40 CFR 63.685(b)(2)

Code of Federal Regulations, 2010 CFR

2010-07-01

... Affected Sources as Required by 40 CFR 63.685(b)(2) 4 Table 4 to Subpart DD of Part 63 Protection of... Hazardous Air Pollutants from Off-Site Waste and Recovery Operations Pt. 63, Subpt. DD, Table 4 Table 4 to Subpart DD of Part 63—Tank Control Levels for Tanks at New Affected Sources as Required by 40 CFR 63.685(b...

The B(E2;4^+1->2^+1) / B(E2;2^+1->0^+1) Ratio in Even-Even Nuclei

NASA Astrophysics Data System (ADS)

Loelius, C.; Sharon, Y. Y.; Zamick, L.; G"Urdal, G.

2009-10-01

We considered 207 even-even nuclei throughout the chart of nuclides for which the NNDC Tables had data on the energies and lifetimes of the 2^+1 and 4^+1 states. Using these data we calculated for each nucleus the electric quadrupole transition strengths B(E2;4^+1->2^+1) and B(E2;2^+1->0^+1), as well as their ratio. The internal conversion coefficients were obtained by using the NNDC HSICC calculator. For each nucleus we plotted the B(E2) ratio against A, N, and Z. We found that for close to 90% of the nuclei considered the ratio had values between 0.5 and 2.5. Most of the outliers had magic numbers of protons or neutrons. Our ratio results were compared with the theoretical predictions for this ratio by different models--10/7 in the rotational model and 2 in the simplest vibrational model. In the rotational regions (for 150 < A < 180 and A > 220) the ratios were indeed close to 10/7. For the few nuclei thought to be vibrational the ratios were usually less than 2. Otherwise, we got a wide scatter of ratio values. Hence other models, including the NpNn scheme, must be considered in interpreting these results.

75 FR 11428 - Airworthiness Directives; Airbus Model A300 B2-1C, B2-203, B2K-3C, B4-103, B4-203, B4-2C...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-11

...-0789; Directorate Identifier 2008-NM-185-AD; Amendment 39-16228; AD 2010-06-04] RIN 2120-AA64..., A310-54-2018 and A300-54-6015. * * * This AD requires the implementation of this * * * inspection... that table were derived from the note in the Configuration 01 table in paragraph 1.E.(2) of Airbus...

50 CFR Table 2b to Part 660... - 2010, and Beyond, Harvest Guidelines for Minor Rockfish by Depth Sub-groups (weights in metric tons)

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false 2010, and Beyond, Harvest Guidelines for Minor Rockfish by Depth Sub-groups (weights in metric tons) 2b Table 2b to Part 660, Subpart G Wildlife... Part 660, Subpart G—2010, and Beyond, Harvest Guidelines for Minor Rockfish by Depth Sub-groups...

49 CFR Table 1 to Subpart B of... - Minimum Coefficient of Retroreflection (RA) (in Candela/Lux/Meter2) Requirement for...

Code of Federal Regulations, 2013 CFR

2013-10-01

...) 1 Table 1 to Subpart B of Part 224 Transportation Other Regulations Relating to Transportation... ROLLING STOCK Application, Inspection, and Maintenance of Retroreflective Material Pt. 224, Subpt. B, Table 1 Table 1 to Subpart B of Part 224—Minimum Coefficient of Retroreflection (RA) (in Candela/Lux...

49 CFR Table 1 to Subpart B of... - Minimum Coefficient of Retroreflection (RA) (in Candela/Lux/Meter2) Requirement for...

Code of Federal Regulations, 2014 CFR

2014-10-01

...) 1 Table 1 to Subpart B of Part 224 Transportation Other Regulations Relating to Transportation... ROLLING STOCK Application, Inspection, and Maintenance of Retroreflective Material Pt. 224, Subpt. B, Table 1 Table 1 to Subpart B of Part 224—Minimum Coefficient of Retroreflection (RA) (in Candela/Lux...

28 CFR Appendix B to Part 79 - Blood-Gas Study Tables

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Blood-Gas Study Tables B Appendix B to... COMPENSATION ACT Pt. 79, App. B Appendix B to Part 79—Blood-Gas Study Tables For arterial blood-gas studies... mmHg 65 mmHg or below. Above 50 mmHg Any value. For arterial blood-gas studies performed at test...

28 CFR Appendix B to Part 79 - Blood-Gas Study Tables

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Blood-Gas Study Tables B Appendix B to... COMPENSATION ACT Pt. 79, App. B Appendix B to Part 79—Blood-Gas Study Tables For arterial blood-gas studies... mmHg 65 mmHg or below. Above 50 mmHg Any value. For arterial blood-gas studies performed at test...

28 CFR Appendix B to Part 79 - Blood-Gas Study Tables

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Blood-Gas Study Tables B Appendix B to... COMPENSATION ACT Pt. 79, App. B Appendix B to Part 79—Blood-Gas Study Tables For arterial blood-gas studies... mmHg 65 mmHg or below. Above 50 mmHg Any value. For arterial blood-gas studies performed at test...

28 CFR Appendix B to Part 79 - Blood-Gas Study Tables

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Blood-Gas Study Tables B Appendix B to... COMPENSATION ACT Pt. 79, App. B Appendix B to Part 79—Blood-Gas Study Tables For arterial blood-gas studies... mmHg 65 mmHg or below. Above 50 mmHg Any value. For arterial blood-gas studies performed at test...

28 CFR Appendix B to Part 79 - Blood-Gas Study Tables

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Blood-Gas Study Tables B Appendix B to... COMPENSATION ACT Pt. 79, App. B Appendix B to Part 79—Blood-Gas Study Tables For arterial blood-gas studies... mmHg 65 mmHg or below. Above 50 mmHg Any value. For arterial blood-gas studies performed at test...

The structure, stability, and infrared spectrum of B 2N, B 2N +, B 2N -, BO, B 2O and B 2N 2.

NASA Astrophysics Data System (ADS)

Martin, J. M. L.; François, J. P.; Gijbels, R.

1992-05-01

The structure, infrared spectrum, and heat of formation of B 2N, B 2N -, BO, and B 2O have been studied ab initio. B 2N is very stable; B 2O even more so. B 2N, B 2N -, B 2O, and probably B 2N + have symmetric linear ground-state structures; for B 2O, an asymmetric linear structure lies about 12 kcal/mol above the ground state. B 2N +, B 2N - and B 2O have intense asymmetric stretching frequencies, predicted near 870, 1590 and 1400 cm -1, respectively. Our predicted harmonic frequencies and isotopic shifts for B 2O confirm the recent experimental identification by Andrews and Burkholder. Absorptions at 1889.5 and 1998.5 cm -1 in noble-gas trapped boron nitride vapor belong the BNB and BNBN ( 3Π), respectively; a tentative assignment of 882.5 cm -1 to BNB + is proposed. Total atomization energies Σ De (Σ D0) are computed (accuracy ±2 kcal/mol) as: BO 193.1 (190.4), B 2O 292.5 (288.7), B 2N 225.0 (250.3) kcal/mol. The ionization potential and electron affinity of B 2N are predicted to be 8.62±0.1 and 3.34±0.1 eV. The MP4-level additivity approximations involved in G1 theory results in errors on the order of 1 kcal/mol in the Σ De values.

31 CFR Appendix B to Part 359 - Composite Semiannual Rate Period Table

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance: Treasury 2 2014-07-01 2014-07-01 false Composite Semiannual Rate Period Table B Appendix B to Part 359 Money and Finance: Treasury Regulations Relating to Money and Finance... SAVINGS BONDS, SERIES I Pt. 359, App. B Appendix B to Part 359—Composite Semiannual Rate Period Table 1...

WASP (Write a Scientific Paper) using Excel - 2: Pivot tables.

PubMed

Grech, Victor

2018-02-01

Data analysis at the descriptive stage and the eventual presentation of results requires the tabulation and summarisation of data. This exercise should always precede inferential statistics. Pivot tables and pivot charts are one of Excel's most powerful and underutilised features, with tabulation functions that immensely facilitate descriptive statistics. Pivot tables permit users to dynamically summarise and cross-tabulate data, create tables in several dimensions, offer a range of summary statistics and can be modified interactively with instant outputs. Large and detailed datasets are thereby easily manipulated making pivot tables arguably the best way to explore, summarise and present data from many different angles. This second paper in the WASP series in Early Human Development provides pointers for pivot table manipulation in Excel™. Copyright © 2018 Elsevier B.V. All rights reserved.

Compendium of Shock Wave Data. Volume 2, Revision 1. Section A2. Inorganic Compounds Section B. Hydrocarbons

DTIC Science & Technology

1977-06-01

5K9AR uret 14’T17 TABLE I TUNGSTEN CARBIDE 53-23--- 1 B i 5 4fL 3 2 0 int IU aF n PAGE 4011.1 ś-1---I RUtILFr. CRYSTAL AND NATURAL (TIIANIUM OXIDCl...COtMIENTS : I I SOURCE: KOIR1ER. 5. B .. SINITSYN. M, V., ruNIIKOV. A, I., UR1. IN. V, a. AND BLINOV . A. V. SOVIET PHYS-.JIEP. VOL. 20. P. 911 119651...AO Uii Coaapendiux of* ýIoek Wave Daa.3otion A2. Inorganuic Compounds. Oection B , "r~iooarbona. ______________ I. Ca"TRACT 09GOAMY wmuimea Lawrt

50 CFR Table 2 to Part 680 - Crab Species Code

Code of Federal Regulations, 2010 CFR

2010-10-01

..., Table 2 Table 2 to Part 680—Crab Species Code Species code Common name Scientific name 900 Box Lopholithodes mandtii. 910 Dungeness Cancer magister. 921 Red king crab Paralithodes camtshaticus. 922 Blue king... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Crab Species Code 2 Table 2 to Part 680...

50 CFR Table 2 to Part 680 - Crab Species Code

Code of Federal Regulations, 2011 CFR

2011-10-01

..., Table 2 Table 2 to Part 680—Crab Species Code Species code Common name Scientific name 900 Box Lopholithodes mandtii. 910 Dungeness Cancer magister. 921 Red king crab Paralithodes camtshaticus. 922 Blue king... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false Crab Species Code 2 Table 2 to Part 680...

K2-30 b and K2-34 b: Two inflated hot Jupiters around solar-type stars

NASA Astrophysics Data System (ADS)

Lillo-Box, J.; Demangeon, O.; Santerne, A.; Barros, S. C. C.; Barrado, D.; Hébrard, G.; Osborn, H. P.; Armstrong, D. J.; Almenara, J.-M.; Boisse, I.; Bouchy, F.; Brown, D. J. A.; Courcol, B.; Deleuil, M.; Delgado Mena, E.; Díaz, R. F.; Kirk, J.; Lam, K. W. F.; McCormac, J.; Pollacco, D.; Rajpurohit, A.; Rey, J.; Santos, N. C.; Sousa, S. G.; Tsantaki, M.; Wilson, P. A.

2016-10-01

We report the discovery of the two hot Jupiters K2-30 b and K2-34 b. The two planets were detected during campaigns 4 and 5 of the extension of the Kepler mission, K2; they transit their main-sequence stars with periods of ~4.099 and ~2.996 days. Subsequent ground-based radial velocity follow-up with SOPHIE, HARPS-N, and CAFE established the planetary nature of the transiting objects. We analyzed the transit signal, radial velocity, and spectral energy distributions of the two systems to characterize their properties. Both planets (K2-30 b and K2-34 b) are bloated hot Jupiters (1.20 RJup and 1.22 RJup) around relatively bright (V = 13.5 and V = 11.5) slow rotating main-sequence (G8 and F9) stars. Thus, these systems are good candidates for detecting the Rossiter-MacLaughlin effect in order to measure their obliquity and for atmospheric studies. Full Tables 1 and 2 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/594/A50

40 CFR Table 2 to Subpart Ffff of... - Emission Limits and Work Practice Standards for Batch Process Vents

Code of Federal Regulations, 2012 CFR

2012-07-01

... Pollutants: Miscellaneous Organic Chemical Manufacturing Pt. 63, Subpt. FFFF, Table 2 Table 2 to Subpart FFFF... Group 1 batch process vents a. Reduce collective uncontrolled organic HAP emissions from the sum of all... a flare); or Not applicable. b. Reduce collective uncontrolled organic HAP emissions from the sum of...

40 CFR Table 2 to Subpart Ffff of... - Emission Limits and Work Practice Standards for Batch Process Vents

Code of Federal Regulations, 2010 CFR

2010-07-01

...: Miscellaneous Organic Chemical Manufacturing Pt. 63, Subpt. FFFF, Table 2 Table 2 to Subpart FFFF of Part 63... vents a. Reduce collective uncontrolled organic HAP emissions from the sum of all batch process vents... applicable. b. Reduce collective uncontrolled organic HAP emissions from the sum of all batch process vents...

40 CFR Table 2 to Subpart Ffff of... - Emission Limits and Work Practice Standards for Batch Process Vents

Code of Federal Regulations, 2011 CFR

2011-07-01

...: Miscellaneous Organic Chemical Manufacturing Pt. 63, Subpt. FFFF, Table 2 Table 2 to Subpart FFFF of Part 63... vents a. Reduce collective uncontrolled organic HAP emissions from the sum of all batch process vents... applicable. b. Reduce collective uncontrolled organic HAP emissions from the sum of all batch process vents...

40 CFR Table 2 to Subpart Lllll of... - Operating Limits

Code of Federal Regulations, 2010 CFR

2010-07-01

...) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing Manufacturing Pt. 63, Subpt. LLLLL, Table 2 Table 2 to Subpart LLLLL of Part 63—Operating Limits For— You must a...

31 CFR Appendix B to Part 359 - Composite Semiannual Rate Period Table

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Composite Semiannual Rate Period... SAVINGS BONDS, SERIES I Pt. 359, App. B Appendix B to Part 359—Composite Semiannual Rate Period Table 1. What months make up the composite semiannual rate period? You may use the following table to find when...

Integrating Multimodal Radiation Therapy Data into i2b2.

PubMed

Zapletal, Eric; Bibault, Jean-Emmanuel; Giraud, Philippe; Burgun, Anita

2018-04-01

 Clinical data warehouses are now widely used to foster clinical and translational research and the Informatics for Integrating Biology and the Bedside (i2b2) platform has become a de facto standard for storing clinical data in many projects. However, to design predictive models and assist in personalized treatment planning in cancer or radiation oncology, all available patient data need to be integrated into i2b2, including radiation therapy data that are currently not addressed in many existing i2b2 sites.  To use radiation therapy data in projects related to rectal cancer patients, we assessed the feasibility of integrating radiation oncology data into the i2b2 platform.  The Georges Pompidou European Hospital, a hospital from the Assistance Publique - Hôpitaux de Paris group, has developed an i2b2-based clinical data warehouse of various structured and unstructured clinical data for research since 2008. To store and reuse various radiation therapy data-dose details, activities scheduling, and dose-volume histogram (DVH) curves-in this repository, we first extracted raw data by using some reverse engineering techniques and a vendor's application programming interface. Then, we implemented a hybrid storage approach by combining the standard i2b2 "Entity-Attribute-Value" storage mechanism with a "JavaScript Object Notation (JSON) document-based" storage mechanism without modifying the i2b2 core tables. Validation was performed using (1) the Business Objects framework for replicating vendor's application screens showing dose details and activities scheduling data and (2) the R software for displaying the DVH curves.  We developed a pipeline to integrate the radiation therapy data into the Georges Pompidou European Hospital i2b2 instance and evaluated it on a cohort of 262 patients. We were able to use the radiation therapy data on a preliminary use case by fetching the DVH curve data from the clinical data warehouse and displaying them in a R chart. �

40 CFR Table A-4 to Subpart A of... - Source Category List for § 98.2(a)(2)

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Source Category List for § 98.2(a)(2) A Table A-4 to Subpart A of Part 98 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING General Provision Pt. 98, Subpt. A...

40 CFR Table A-4 to Subpart A of... - Source Category List for § 98.2(a)(2)

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Source Category List for § 98.2(a)(2) A Table A-4 to Subpart A of Part 98 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING General Provision Pt. 98, Subpt. A...

40 CFR Table A-4 to Subpart A of... - Source Category List for § 98.2(a)(2)

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Source Category List for § 98.2(a)(2) A Table A-4 to Subpart A of Part 98 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING General Provision Pt. 98, Subpt. A...

A Clinical Data Warehouse Based on OMOP and i2b2 for Austrian Health Claims Data.

PubMed

Rinner, Christoph; Gezgin, Deniz; Wendl, Christopher; Gall, Walter

2018-01-01

To develop simulation models for healthcare related questions clinical data can be reused. Develop a clinical data warehouse to harmonize different data sources in a standardized manner and get a reproducible interface for clinical data reuse. The Kimball life cycle for the development of data warehouse was used. The development is split into the technical, the data and the business intelligence pathway. Sample data was persisted in the Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM). The i2b2 clinical data warehouse tools were used to query the OMOP CDM by applying the new i2b2 multi-fact table feature. A clinical data warehouse was set up and sample data, data dimensions and ontologies for Austrian health claims data were created. The ability of the standardized data access layer to create and apply simulation models will be evaluated next.

Comparison of Oregon state highway division Table-1 and Table-2 asphalt : final report.

DOT National Transportation Integrated Search

1991-12-01

The objective of this study was to compare the effect of using the Oregon State Highway Division (OSHD) modified Table-1 asphalts and the OSHD modified Table-2 asphalts in asphalt concrete; the primary factors for comparison were reflective and therm...

The Vaporization of B2O3(l) to B2O3(g) and B2O2(g)

NASA Technical Reports Server (NTRS)

Jacobson, Nathan S.; Myers, Dwight L.

2011-01-01

The vaporization of B2O3 in a reducing environment leads to formation of both B2O3(g) and B2O2(g). While formation of B2O3(g) is well understood, many questions about the formation of B2O2(g) remain. Previous studies using B(s) + B2O3(l) have led to inconsistent thermodynamic data. In this study, it was found that after heating, B(s) and B2O3(l) appear to separate and variations in contact area likely led to the inconsistent vapor pressures of B2O2(g). To circumvent this problem, an activity of boron is fixed with a two-phase mixture of FeB and Fe2B. Both second and third law enthalpies of formation were measured for B2O2(g) and B2O3(g). From these the enthalpies of formation at 298.15 K are calculated to be -479.9 +/- 41.5 kJ/mol for B2O2(g) and -833.4 +/- 13.1 kJ/mol for B2O3(g). Ab initio calculations to determine the enthalpies of formation of B2O2(g) and B2O3(g) were conducted using the W1BD composite method and show good agreement with the experimental values.

40 CFR Table 2 to Subpart Hhh of... - Toxic Equivalency Factors

Code of Federal Regulations, 2010 CFR

2010-07-01

..., Subpt. HHH, Table 2 Table 2 to Subpart HHH of Part 62—Toxic Equivalency Factors Dioxin/furan congener Toxic equivalency factor 2,3,7,8-tetrachlorinated dibenzo-p-dioxin 1 1,2,3,7,8-pentachlorinated dibenzo-p-dioxin 0.5 1,2,3,4,7,8-hexachlorinated dibenzo-p-dioxin 0.1 1,2,3,7,8,9-hexachlorinated dibenzo-p...

40 CFR Table 2 to Subpart Ttttt of... - Toxic Equivalency Factors

Code of Federal Regulations, 2010 CFR

2010-07-01

..., Subpt. TTTTT, Table 2 Table 2 to Subpart TTTTT of Part 63—Toxic Equivalency Factors Dioxin/furan congener Toxic equivalency factor 2,3,7,8-tetrachlorinated dibenzo-p-dioxin 1 1,2,3,7,8-pentachlorinated dibenzo-p-dioxin 1 1,2,3,4,7,8-hexachlorinated dibenzo-p-dioxin 0.1 1,2,3,7,8,9-hexachlorinated dibenzo-p...

A PCV2 vaccine based on genotype 2b is more effective than a 2a-based vaccine to protect against PCV2b or combined PCV2a/2b viremia in pigs with concurrent PCV2, PRRSV and PPV infection.

PubMed

Opriessnig, Tanja; O'Neill, Kevin; Gerber, Priscilla F; de Castro, Alessandra M M G; Gimenéz-Lirola, Luis G; Beach, Nathan M; Zhou, Lei; Meng, Xiang-Jin; Wang, Chong; Halbur, Patrick G

2013-01-07

The predominant genotype of porcine circovirus (PCV) in the pig population today is PCV2b yet PCV2a-based commercial vaccines are considered effective in protecting against porcine circovirus associated disease. The objective of this study was to compare the ability of PCV2a- and PCV2b-based vaccines to control PCV2b viremia in a challenge model that mimics the U.S. field situation. Sixty-three pigs were randomly assigned to one of eight groups. Sixteen pigs were vaccinated with an experimental live-attenuated chimeric PCV1-2a vaccine based on genotype 2a and another 16 pigs with a chimeric PCV1-2b vaccine based on genotype 2b. Challenge was done 28 days post vaccination (dpv) using PCV2b (or a combination of PCV2a and PCV2b), porcine reproductive and respiratory syndrome virus (PRRSV), and porcine parvovirus (PPV) to mimic what commonly occurs in the field. The experiment was terminated 21 days post challenge (dpc) or 49dpv. Pigs vaccinated with the chimeric PCV1-2b vaccine had significantly higher levels of PCV1-2b viremia and shedding of the PCV1-2b vaccine virus in feces and nasal secretions but also a more robust humoral immune response as evidenced by significantly higher ELISA S/P ratios compared to the PCV1-2a vaccination. Regardless of challenge, the PCV1-2b vaccination significantly reduced the prevalence and amount of PCV2 viremia compared to the PCV1-2a vaccination. Interestingly, in the non-vaccinated pigs concurrent PCV2a infection resulted in clinical disease and increased macroscopic lung lesions compared to pigs challenged with PCV2b alone, further supporting the idea that concurrent PCV2a/PCV2b infection is necessary for optimal PCV2 replication. Copyright © 2012 Elsevier Ltd. All rights reserved.

Bu-2470, a new peptide antibiotic complex. II. Structure determination of Bu-2470 A, B1, B2a and B2b.

PubMed

Sugawara, K; Yonemoto, T; Konishi, M; Matsumoto, K; Miyaki, T; Kawaguchi, H

1983-06-01

The structures of Bu-2470 A, B1, B2a, and B2b have been determined. Bu-2470 A is a simple octapeptide having no fatty acid moiety, while Bu-2470 B1, B2a and B2b are octapeptides that have been acylated with a beta-hydroxy C11 or C10 fatty acid. The octapeptide structure of Bu-2470 components was found identical with that of octapeptin C1, hence generic names of octapeptin C0, C2, C3 and C4 are proposed for Bu-2470 A, B1, B2a and B2b, respectively.

CARDIO-i2b2: integrating arrhythmogenic disease data in i2b2.

PubMed

Segagni, Daniele; Tibollo, Valentina; Dagliati, Arianna; Napolitano, Carlo; G Priori, Silvia; Bellazzi, Riccardo

2012-01-01

The CARDIO-i2b2 project is an initiative to customize the i2b2 bioinformatics tool with the aim to integrate clinical and research data in order to support translational research in cardiology. In this work we describe the implementation and the customization of i2b2 to manage the data of arrhytmogenic disease patients collected at the Fondazione Salvatore Maugeri of Pavia in a joint project with the NYU Langone Medical Center (New York, USA). The i2b2 clinical research chart data warehouse is populated with the data obtained by the research database called TRIAD. The research infrastructure is extended by the development of new plug-ins for the i2b2 web client application able to properly select and export phenotypic data and to perform data analysis.

40 CFR Table B-3 to Subpart B of... - Interferent Test Concentration, Parts per Million

Code of Federal Regulations, 2012 CFR

2012-07-01

... per Million B Table B-3 to Subpart B of Part 53 Protection of Environment ENVIRONMENTAL PROTECTION..., Subpt. B, Table B-3 Table B-3 to Subpart B of Part 53—Interferent Test Concentration, Parts per Million Table B-3 to Subpart B of Part 53—Interferent Test Concentration,1 Parts per Million Pollutant Analyzer...

Olfactomedin-like 2 A and B (OLFML2A and OLFML2B) expression profile in primates (human and baboon).

PubMed

Pérez-Ibave, Diana Cristina; González-Alvarez, Rafael; de La Luz Martinez-Fierro, Margarita; Ruiz-Ayma, Gabriel; Luna-Muñoz, Maricela; Martínez-De-Villarreal, Laura Elia; De Lourdes Garza-Rodríguez, María; Reséndez-Pérez, Diana; Mohamed-Noriega, Jibran; Garza-Guajardo, Raquel; Bautista-De-Lucío, Víctor Manuel; Mohamed-Noriega, Karim; Barboza-Quintana, Oralia; Arámburo-De-La-Hoz, Carlos; Barrera-Saldaña, Hugo Alberto; Rodríguez-Sánchez, Irám Pablo

2016-11-08

The olfactomedin-like domain (OLFML) is present in at least four families of proteins, including OLFML2A and OLFML2B, which are expressed in adult rat retina cells. However, no expression of their orthologous has ever been reported in human and baboon. The aim of this study was to investigate the expression of OLFML2A and OLFML2B in ocular tissues of baboons (Papio hamadryas) and humans, as a key to elucidate OLFML function in eye physiology. OLFML2A and OLFML2B cDNA detection in ocular tissues of these species was performed by RT-PCR. The amplicons were cloned and sequenced, phylogenetically analyzed and their proteins products were confirmed by immunofluorescence assays. OLFML2A and OLFML2B transcripts were found in human cornea, lens and retina and in baboon cornea, lens, iris and retina. The baboon OLFML2A and OLFML2B ORF sequences have 96% similarity with their human's orthologous. OLFML2A and OLFML2B evolution fits the hypothesis of purifying selection. Phylogenetic analysis shows clear orthology in OLFML2A genes, while OLFML2B orthology is not clear. Expression of OLFML2A and OLFML2B in human and baboon ocular tissues, including their high similarity, make the baboon a powerful model to deduce the physiological and/or metabolic function of these proteins in the eye.

40 CFR Table 2 to Subpart Cb of... - Nitrogen Oxides Limits for Existing Designated Facilities Included in an Emissions Averaging Plan...

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Nitrogen Oxides Limits for Existing.... 60, Subpt. Cb, Table 2 Table 2 to Subpart Cb of Part 60—Nitrogen Oxides Limits for Existing... by volume) b On and after April 28, 2009, nitrogen oxides emission limit (parts permillion by volume...

40 CFR Table 2 to Subpart Cb of... - Nitrogen Oxides Limits for Existing Designated Facilities Included in an Emissions Averaging Plan...

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 7 2013-07-01 2013-07-01 false Nitrogen Oxides Limits for Existing.... 60, Subpt. Cb, Table 2 Table 2 to Subpart Cb of Part 60—Nitrogen Oxides Limits for Existing... by volume) b On and after April 28, 2009, nitrogen oxides emission limit (parts permillion by volume...

40 CFR Table 2 to Subpart Cb of... - Nitrogen Oxides Limits for Existing Designated Facilities Included in an Emissions Averaging Plan...

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 7 2014-07-01 2014-07-01 false Nitrogen Oxides Limits for Existing.... 60, Subpt. Cb, Table 2 Table 2 to Subpart Cb of Part 60—Nitrogen Oxides Limits for Existing... by volume) b On and after April 28, 2009, nitrogen oxides emission limit (parts permillion by volume...

40 CFR Table 2 to Subpart Cb of... - Nitrogen Oxides Limits for Existing Designated Facilities Included in an Emissions Averaging Plan...

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 7 2012-07-01 2012-07-01 false Nitrogen Oxides Limits for Existing.... 60, Subpt. Cb, Table 2 Table 2 to Subpart Cb of Part 60—Nitrogen Oxides Limits for Existing... by volume) b On and after April 28, 2009, nitrogen oxides emission limit (parts permillion by volume...

40 CFR Table 2 to Subpart Cb of... - Nitrogen Oxides Limits for Existing Designated Facilities Included in an Emissions Averaging Plan...

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 6 2011-07-01 2011-07-01 false Nitrogen Oxides Limits for Existing.... 60, Subpt. Cb, Table 2 Table 2 to Subpart Cb of Part 60—Nitrogen Oxides Limits for Existing... by volume) b On and after April 28, 2009, nitrogen oxides emission limit (parts permillion by volume...

40 CFR Table C-2 to Subpart C of... - Sequence of Test Measurements

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 6 2013-07-01 2013-07-01 false Sequence of Test Measurements C Table C-2 to Subpart C of Part 53 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Comparability Between Candidate Methods and Reference Methods Pt. 53, Subpt. C, Table C-2 Table C-2 to Subpart C...

40 CFR Table C-2 to Subpart C of... - Sequence of Test Measurements

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 6 2014-07-01 2014-07-01 false Sequence of Test Measurements C Table C-2 to Subpart C of Part 53 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Comparability Between Candidate Methods and Reference Methods Pt. 53, Subpt. C, Table C-2 Table C-2 to Subpart C...

40 CFR Table C-2 to Subpart C of... - Sequence of Test Measurements

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 6 2012-07-01 2012-07-01 false Sequence of Test Measurements C Table C-2 to Subpart C of Part 53 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Comparability Between Candidate Methods and Reference Methods Pt. 53, Subpt. C, Table C-2 Table C-2 to Subpart C...

40 CFR Table C-2 to Subpart C of... - Sequence of Test Measurements

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 5 2011-07-01 2011-07-01 false Sequence of Test Measurements C Table C-2 to Subpart C of Part 53 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Comparability Between Candidate Methods and Reference Methods Pt. 53, Subpt. C, Table C-2 Table C-2 to Subpart C...

40 CFR Table C-2 to Subpart C of... - Sequence of Test Measurements

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Sequence of Test Measurements C Table C-2 to Subpart C of Part 53 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Comparability Between Candidate Methods and Reference Methods Pt. 53, Subpt. C, Table C-2 Table C-2 to Subpart C...

40 CFR Table C-2 to Subpart C - Default CH4 and N2O Emission Factors for Various Types of Fuel

Code of Federal Regulations, 2012 CFR

2012-07-01

... for Various Types of Fuel C Table C-2 to Subpart C Protection of Environment ENVIRONMENTAL PROTECTION... Combustion Sources Pt. 98, Subpt. C, Table C-2 Table C-2 to Subpart C—Default CH4 and N2O Emission Factors... factor (kg N2O/mmBtu) Coal and Coke (All fuel types in Table C-1) 1.1 × 10−02 1.6 × 10−03 Natural Gas 1.0...

40 CFR Table C-2 to Subpart C - Default CH4 and N2O Emission Factors for Various Types of Fuel

Code of Federal Regulations, 2011 CFR

2011-07-01

... for Various Types of Fuel C Table C-2 to Subpart C Protection of Environment ENVIRONMENTAL PROTECTION... Combustion Sources Pt. 98, Subpt. C, Table C-2 Table C-2 to Subpart C—Default CH4 and N2O Emission Factors... factor (kg N2O/mmBtu) Coal and Coke (All fuel types in Table C-1) 1.1 × 10−02 1.6 × 10−03 Natural Gas 1.0...

Longitudinal Surveys of Australian Youth (LSAY) 2009 Cohort: Wave 2 (2010)--Frequency Tables. Technical Report 71B

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2012

2012-01-01

The Longitudinal Surveys of Australian Youth (LSAY) program studies the progress of several groups of young Australians as they move from school into post-secondary education and work. This technical paper contains the frequency tables for the LSAY 2009 cohort Wave 2 (2010) data set.

40 CFR Table Mm-2 to Subpart Mm of... - Default Factors for Biomass-Based Fuels and Biomass

Code of Federal Regulations, 2011 CFR

2011-07-01

... Fuels and Biomass MM Table MM-2 to Subpart MM of Part 98 Protection of Environment ENVIRONMENTAL... Biomass-Based Fuels and Biomass Biomass-based fuel and biomass Column A:Density (metric tons/bbl) Column B: Carbon share(% of mass) Column C:Emission factor (metric tons CO2/bbl) Ethanol (100%) 0.1267 52.14 0.2422...

40 CFR Table Mm-2 to Subpart Mm of... - Default Factors for Biomass-Based Fuels and Biomass

Code of Federal Regulations, 2013 CFR

2013-07-01

... Fuels and Biomass MM Table MM-2 to Subpart MM of Part 98 Protection of Environment ENVIRONMENTAL... Biomass-Based Fuels and Biomass Biomass-based fuel and biomass Column A:Density (metric tons/bbl) Column B: Carbon share(% of mass) Column C:Emission factor (metric tons CO2/bbl) Ethanol (100%) 0.1267 52.14 0.2422...

40 CFR Table Mm-2 to Subpart Mm of... - Default Factors for Biomass-Based Fuels and Biomass

Code of Federal Regulations, 2014 CFR

2014-07-01

... Fuels and Biomass MM Table MM-2 to Subpart MM of Part 98 Protection of Environment ENVIRONMENTAL... Biomass-Based Fuels and Biomass Biomass-based fuel and biomass Column A:Density (metric tons/bbl) Column B: Carbon share(% of mass) Column C:Emission factor (metric tons CO2/bbl) Ethanol (100%) 0.1267 52.14 0.2422...

40 CFR Table Mm-2 to Subpart Mm of... - Default Factors for Biomass-Based Fuels and Biomass

Code of Federal Regulations, 2012 CFR

2012-07-01

... Fuels and Biomass MM Table MM-2 to Subpart MM of Part 98 Protection of Environment ENVIRONMENTAL... Biomass-Based Fuels and Biomass Biomass-based fuel and biomass Column A:Density (metric tons/bbl) Column B: Carbon share(% of mass) Column C:Emission factor (metric tons CO2/bbl) Ethanol (100%) 0.1267 52.14 0.2422...

40 CFR Table Nn-2 to Subpart Hh of... - Lookup Default Values for Calculation Methodology 2 of This Subpart

Code of Federal Regulations, 2011 CFR

2011-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Municipal Solid Waste Landfills Pt. 98, Subpt. NN, Table NN-2 Table NN-2 to Subpart HH of Part 98—Lookup Default Values...

Application tables for MIL-STD-461B

NASA Astrophysics Data System (ADS)

Schulz, R. B.

1982-02-01

The complexity in application of MIL-STD-461B is reduced by use of tables which summarize requirements of the standard. A separate table is provided for a group of limits applicable to each type of test procedure.

40 CFR Table 2 to Subpart F of... - Organic Hazardous Air Pollutants

Code of Federal Regulations, 2013 CFR

2013-07-01

... CATEGORIES National Emission Standards for Organic Hazardous Air Pollutants From the Synthetic Organic Chemical Manufacturing Industry Pt. 63, Subpt. F, Table 2 Table 2 to Subpart F of Part 63—Organic Hazardous... 40 Protection of Environment 10 2013-07-01 2013-07-01 false Organic Hazardous Air Pollutants 2...

40 CFR Table 2 to Subpart F of... - Organic Hazardous Air Pollutants

Code of Federal Regulations, 2011 CFR

2011-07-01

... CATEGORIES National Emission Standards for Organic Hazardous Air Pollutants From the Synthetic Organic Chemical Manufacturing Industry Pt. 63, Subpt. F, Table 2 Table 2 to Subpart F of Part 63—Organic Hazardous... 40 Protection of Environment 9 2011-07-01 2011-07-01 false Organic Hazardous Air Pollutants 2...

40 CFR Table 2 to Subpart F of... - Organic Hazardous Air Pollutants

Code of Federal Regulations, 2014 CFR

2014-07-01

... CATEGORIES National Emission Standards for Organic Hazardous Air Pollutants From the Synthetic Organic Chemical Manufacturing Industry Pt. 63, Subpt. F, Table 2 Table 2 to Subpart F of Part 63—Organic Hazardous... 40 Protection of Environment 10 2014-07-01 2014-07-01 false Organic Hazardous Air Pollutants 2...

40 CFR Table 2 to Subpart Fff of... - Nitrogen Oxides Requirements for Affected Facilities

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Nitrogen Oxides Requirements for Affected Facilities 2 Table 2 to Subpart FFF of Part 62 Protection of Environment ENVIRONMENTAL PROTECTION... Before September 20, 1994 Pt. 62, Subpt. FFF, Table 2 Table 2 to Subpart FFF of Part 62—Nitrogen Oxides...

40 CFR Table 2 to Subpart Jj of... - List of Volatile Hazardous Air Pollutants

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 10 2010-07-01 2010-07-01 false List of Volatile Hazardous Air Pollutants 2 Table 2 to Subpart JJ of Part 63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY.... JJ, Table 2 Table 2 to Subpart JJ of Part 63—List of Volatile Hazardous Air Pollutants Chemical name...

Effect of water table management and elevated CO2 on radish productivity and on CH4 and CO2 fluxes from peatlands converted to agriculture.

PubMed

Musarika, S; Atherton, C E; Gomersall, T; Wells, M J; Kaduk, J; Cumming, A M J; Page, S E; Oechel, W C; Zona, D

2017-04-15

Anthropogenic activity is affecting the global climate through the release of greenhouse gases (GHGs) e.g. CO 2 and CH 4 . About a third of anthropogenic GHGs are produced from agriculture, including livestock farming and horticulture. A large proportion of the UK's horticultural farming takes place on drained lowland peatlands, which are a source of significant amounts of CO 2 into the atmosphere. This study set out to establish whether raising the water table from the currently used -50cm to -30cm could reduce GHGs emissions from agricultural peatlands, while simultaneously maintaining the current levels of horticultural productivity. A factorial design experiment used agricultural peat soil collected from the Norfolk Fens (among the largest of the UK's lowland peatlands under intensive cultivation) to assess the effects of water table levels, elevated CO 2 , and agricultural production on GHG fluxes and crop productivity of radish, one of the most economically important fenland crops. The results of this study show that a water table of -30cm can increase the productivity of the radish crop while also reducing soil CO 2 emissions but without a resultant loss of CH 4 to the atmosphere, under both ambient and elevated CO 2 concentrations. Elevated CO 2 increased dry shoot biomass, but not bulb biomass nor root biomass, suggesting no immediate advantage of future CO 2 levels to horticultural farming on peat soils. Overall, increasing the water table could make an important contribution to global warming mitigation while not having a detrimental impact on crop yield. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

Vibrational Energy Transfer within the B 3Pi (0(+) sub u) State of 79BR2 Upon Collision with N2, O2, NO, and SF6

DTIC Science & Technology

1993-12-01

molecular radii derived for a (6,12) Lennard - Jones potential from viscosity data tabulated in reference (7). 49 Table A. 1. Gas Kinetic Collision...transfer rates and electronic quenching rates of the diatomic interhalogens in determining potential candidates for visible chemical lasers. This thesis...configuration ..................... 4 2. B2 potential energy curves ................................................................... 5 3. Simplified

40 CFR Appendix - Tables to Subpart B of Part 88

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Tables to Subpart B of Part 88 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CLEAN-FUEL VEHICLES California Pilot Test Program State opt-in for the California Pilot Test Program. Pt. 88, Subpt. B, Tables Tables to Subpart B of Part 88 Tabl...

40 CFR Table C-2 to Subpart C of... - Default CH4 and N2O Emission Factors for Various Types of Fuel

Code of Federal Regulations, 2013 CFR

2013-07-01

... for Various Types of Fuel C Table C-2 to Subpart C of Part 98 Protection of Environment ENVIRONMENTAL... Fuel Combustion Sources Pt. 98, Subpt. C, Table C-2 Table C-2 to Subpart C of Part 98—Default CH4 and...) Default N2O emission factor (kg N2O/mmBtu) Coal and Coke (All fuel types in Table C-1) 1.1 × 10−02 1.6...

40 CFR Table C-2 to Subpart C of... - Default CH4 and N2O Emission Factors for Various Types of Fuel

Code of Federal Regulations, 2014 CFR

2014-07-01

... for Various Types of Fuel C Table C-2 to Subpart C of Part 98 Protection of Environment ENVIRONMENTAL... Fuel Combustion Sources Pt. 98, Subpt. C, Table C-2 Table C-2 to Subpart C of Part 98—Default CH4 and...) Default N2O emission factor (kg N2O/mmBtu) Coal and Coke (All fuel types in Table C-1) 1.1 × 10− 02 1.6...

50 CFR Table 2d to Part 660... - At-Sea Whiting Fishery Annual Set-Asides, 2012 and beyond

Code of Federal Regulations, 2012 CFR

2012-10-01

... Annual Set-Asides, 2012 and beyond Species or species complex Set-aside (mt) Lingcod 6 Pacific Cod 5 Pacific Whiting Allocation a Sablefish N. of 36° 50 Sablefish S. of 36° NA PACIFIC OCEAN PERCH Allocation... Pacific Halibut 10 b a/ See Table 2.b., to Subpart C, for the at-sea whiting allocations for these species...

40 CFR Table Nn-2 to Subpart Nn of... - Default Values for Calculation Methodology 2 of This Subpart

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Suppliers of Natural Gas and Natural Gas Liquids Pt. 98, Subpt. NN, Table NN-2 Table NN-2 to Subpart NN of Part 98.../Unit) 1 Natural Gas Mscf 0.0544 Propane Barrel 0.241 Normal butane Barrel 0.281 Ethane Barrel 0.170...

40 CFR Table 2 to Subpart Cccc of... - Operating Limits for Wet Scrubbers

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Operating Limits for Wet Scrubbers 2..., Subpt. CCCC, Table 2 Table 2 to Subpart CCCC of Part 60—Operating Limits for Wet Scrubbers For these... units) 3-hour rolling (continuous and intermittent units) a Pressure drop across the wet scrubber or...

40 CFR Table 2 to Subpart Cccc of... - Operating Limits for Wet Scrubbers

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 6 2011-07-01 2011-07-01 false Operating Limits for Wet Scrubbers 2..., Subpt. CCCC, Table 2 Table 2 to Subpart CCCC of Part 60—Operating Limits for Wet Scrubbers For these... units) 3-hour rolling (continuous and intermittent units) a Pressure drop across the wet scrubber or...

40 CFR Table B-3 to Subpart B of... - Interferent Test Concentration,1 Parts per Million

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 6 2014-07-01 2014-07-01 false Interferent Test Concentration,1 Parts per Million B Table B-3 to Subpart B of Part 53 Protection of Environment ENVIRONMENTAL PROTECTION..., Subpt. B, Table B-3 Table B-3 to Subpart B of Part 53—Interferent Test Concentration,1 Parts per Million...

40 CFR Table 2 to Subpart Ssss of... - Applicability of General Provisions to Subpart SSSS

Code of Federal Regulations, 2010 CFR

2010-07-01

... Subpart SSSS 2 Table 2 to Subpart SSSS of Part 63 Protection of Environment ENVIRONMENTAL PROTECTION... Pt. 63, Subpt. SSSS, Table 2 Table 2 to Subpart SSSS of Part 63—Applicability of General Provisions to Subpart SSSS You must comply with the applicable General Provisions requirements according to the...

Botrytis californica, a new cryptic species in the B. cinerea species complex causing gray mold in blueberries and table grapes.

PubMed

Saito, S; Margosan, D; Michailides, T J; Xiao, C L

2016-01-01

The Botrytis cinerea species complex comprises two cryptic species, originally referred to Group I and Group II based on Bc-hch gene RFLP haplotyping. Group I was described as a new cryptic species B. pseudocinerea During a survey of Botrytis spp. causing gray mold in blueberries and table grapes in the Central Valley of California, six isolates, three from blueberries and three from table grapes, were placed in Group I but had a distinct morphological character with conidiophores significantly longer than those of B. cinerea and B. pseudocinerea We compared these with B. cinerea and B. pseudocinerea by examining morphological and physiological characters, sensitivity to fenhexamid and phylogenetic analysis inferred from sequences of three nuclear genes. Phylogenetic analysis with the three partial gene sequences encoding glyceraldehyde-3-phosate dehydrogenase (G3PDH), heat-shock protein 60 (HSP60) and DNA-dependent RNA polymerase subunit II (RPB2) supported the proposal of a new Botrytis species, B. californica, which is closely related genetically to B. cinerea, B. pseudocinerea and B. sinoviticola, all known as causal agents of gray mold of grapes. Botrytis californica caused decay on blueberry and table grape fruit inoculated with the fungus. This study suggests that B. californica is a cryptic species sympatric with B. cinerea on blueberries and table grapes in California. © 2016 by The Mycological Society of America.

40 CFR Table 2 to Subpart X of... - Emissions Limits for Secondary Lead Smelting Furnaces

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 10 2014-07-01 2014-07-01 false Emissions Limits for Secondary Lead Smelting Furnaces 2 Table 2 to Subpart X of Part 63 Protection of Environment ENVIRONMENTAL PROTECTION... Pt. 63, Subpt. X, Table 2 Table 2 to Subpart X of Part 63—Emissions Limits for Secondary Lead...

40 CFR Table 2 to Subpart X of... - Emissions Limits for Secondary Lead Smelting Furnaces

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 10 2013-07-01 2013-07-01 false Emissions Limits for Secondary Lead Smelting Furnaces 2 Table 2 to Subpart X of Part 63 Protection of Environment ENVIRONMENTAL PROTECTION... Pt. 63, Subpt. X, Table 2 Table 2 to Subpart X of Part 63—Emissions Limits for Secondary Lead...

40 CFR Table 2 to Subpart X of... - Emissions Limits for Secondary Lead Smelting Furnaces

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 10 2012-07-01 2012-07-01 false Emissions Limits for Secondary Lead Smelting Furnaces 2 Table 2 to Subpart X of Part 63 Protection of Environment ENVIRONMENTAL PROTECTION... Pt. 63, Subpt. X, Table 2 Table 2 to Subpart X of Part 63—Emissions Limits for Secondary Lead...

40 CFR Appendix - Tables to Subpart B of Part 88

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 21 2012-07-01 2012-07-01 false Tables to Subpart B of Part 88 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CLEAN-FUEL VEHICLES California Pilot Test Program State opt-in for the California Pilot Test Program. Pt. 88, Subpt. B, Tables Tables to Subpart B of Part 88...

40 CFR Appendix - Tables to Subpart B of Part 88

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 21 2013-07-01 2013-07-01 false Tables to Subpart B of Part 88 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CLEAN-FUEL VEHICLES California Pilot Test Program State opt-in for the California Pilot Test Program. Pt. 88, Subpt. B, Tables Tables to Subpart B of Part 88...

40 CFR Appendix - Tables to Subpart B of Part 88

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Tables to Subpart B of Part 88 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CLEAN-FUEL VEHICLES California Pilot Test Program State opt-in for the California Pilot Test Program. Pt. 88, Subpart B, Tables Tables to Subpart B of Part 88...

40 CFR Appendix - Tables to Subpart B of Part 88

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 20 2011-07-01 2011-07-01 false Tables to Subpart B of Part 88 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CLEAN-FUEL VEHICLES California Pilot Test Program State opt-in for the California Pilot Test Program. Pt. 88, Subpart B, Tables Tables to Subpart B of Part 88...

40 CFR Table Aa-2 to Subpart Aa of... - Kraft Lime Kiln and Calciner Emissions Factors for CH4 and N2O

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Kraft Lime Kiln and Calciner Emissions Factors for CH4 and N2O AA Table AA-2 to Subpart AA of Part 98 Protection of Environment ENVIRONMENTAL... Manufacturing Pt. 98, Subpt. AA, Table AA -2 Table AA-2 to Subpart AA of Part 98—Kraft Lime Kiln and Calciner...

32 CFR Attachment D to Subpart B... - Decision Tables

Code of Federal Regulations, 2011 CFR

2011-07-01

... date NACLC or SSBI Conf, Sec; “L” Top Secret, SCI; “Q” None None SSBI B None; Conf, Sec; “L” Current or out of date NACLC Out of date SSBI TS, SCI; “Q” SSBI-PR C Table 2—Reinvestigation Requirements If the... NACLC Secret; “L” 0 to 9 yrs 11 mos None (note 1) 10 yrs. or more NACLC Top Secret, SCI; “Q” 0 to 4 yrs...

40 CFR Table 2 to Subpart IIIii of... - Work Practice Standards-Required Inspections

Code of Federal Regulations, 2010 CFR

2010-07-01

... Mercury Cell Chlor-Alkali Plants Pt. 63, Subpt. IIIII, Table 2 Table 2 to Subpart IIIII of Part 63—Work... must . . . 1. Each vent hose on each mercury cell Half day A leaking vent hose Take action immediately... mercury seal pot stopper securely in place. 6. Cell room floors Month Cracks, spalling, or other...

40 CFR Table Jj-2 to Subpart Jj of... - Waste Characteristics Data

Code of Federal Regulations, 2014 CFR

2014-07-01

... animal mass) Maximum methane generation potential, Bo (m3 CH4/kg VS added) Dairy Cows 604 See Table JJ-3 See Table JJ-3 0.24 Dairy Heifers 476 See Table JJ-3 See Table JJ-3 0.17 Dairy Calves 118 6.41 0.30 0... JJ-3 0.33 Market Swine 180 lbs 91 5.40 0.42 0.48 Breeding Swine 198 2.60 0.24 0.48 Feedlot Sheep 25 9...

40 CFR Table Jj-2 to Subpart Jj of... - Waste Characteristics Data

Code of Federal Regulations, 2013 CFR

2013-07-01

... animal mass) Maximum methane generation potential, Bo (m3 CH4/kg VS added) Dairy Cows 604 See Table JJ-3 See Table JJ-3 0.24 Dairy Heifers 476 See Table JJ-3 See Table JJ-3 0.17 Dairy Calves 118 6.41 0.30 0... JJ-3 0.33 Market Swine 180 lbs 91 5.40 0.42 0.48 Breeding Swine 198 2.60 0.24 0.48 Feedlot Sheep 25 9...

40 CFR Table Jj-2 to Subpart Jj of... - Waste Characteristics Data

Code of Federal Regulations, 2012 CFR

2012-07-01

... animal mass) Maximum methane generation potential, Bo (m3 CH4/kg VS added) Dairy Cows 604 See Table JJ-3 See Table JJ-3 0.24 Dairy Heifers 476 See Table JJ-3 See Table JJ-3 0.17 Dairy Calves 118 6.41 0.30 0... JJ-3 0.33 Market Swine 180 lbs 91 5.40 0.42 0.48 Breeding Swine 198 2.60 0.24 0.48 Feedlot Sheep 25 9...

B11 NMR in the layered diborides OsB2 and RuB2

NASA Astrophysics Data System (ADS)

Suh, B. J.; Zong, X.; Singh, Y.; Niazi, A.; Johnston, D. C.

2007-10-01

B11 nuclear magnetic resonance (NMR) measurements have been performed on B11 enriched OsB2 and RuB2 polycrystalline powder samples in an external field of 4.7T and in the temperature range, 4.2Ka nonaxial symmetry. The Knight shifts K in both samples are very small and constant in temperature. The nuclear spin-lattice relaxation rate T1-1 follows a Korringa law in the whole temperature range investigated with T1T=600 and 680sK for OsB2 and RuB2 , respectively. The experimental results indicate that a p character dominates the conduction electron wave function at the B site with a negligibly small s character in both compounds.

40 CFR Table 2 to Subpart Aaaaa of... - Operating Limits

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 14 2012-07-01 2011-07-01 true Operating Limits 2 Table 2 to Subpart... (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Lime Manufacturing Plants Part 63, Subpt...

40 CFR Table 2 to Subpart Aaaaa of... - Operating Limits

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 13 2010-07-01 2010-07-01 false Operating Limits 2 Table 2 to Subpart... (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Lime Manufacturing Plants Part 63, Subpt...

40 CFR Table 2 to Subpart Aaaaa of... - Operating Limits

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 13 2011-07-01 2011-07-01 false Operating Limits 2 Table 2 to Subpart... (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Lime Manufacturing Plants Part 63, Subpt...

40 CFR Table 2 to Subpart U of... - Applicability of Subparts F, G, & H of This Part to Subpart U Affected Sources

Code of Federal Regulations, 2010 CFR

2010-07-01

...: Group I Polymers and Resins Pt. 63, Subpt. U, Table 2 Table 2 to Subpart U of Part 63—Applicability of... § 63.482. § 63.112 No §§ 63.113-63.118 Yes With the differences noted in § 63.485 (b) through § 63.485(k) §§ 63.119-63.123 Yes With the differences noted in § 63.484(c) through 63.484(s) 63.484. §§ 63...

40 CFR Table 2 to Subpart Aaaaa of... - Operating Limits

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 14 2013-07-01 2013-07-01 false Operating Limits 2 Table 2 to Subpart... (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Lime Manufacturing Plants Pt. 63, Subpt. AAAAA...

40 CFR Table 2 to Subpart Aaaaa of... - Operating Limits

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 14 2014-07-01 2014-07-01 false Operating Limits 2 Table 2 to Subpart... (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Lime Manufacturing Plants Pt. 63, Subpt. AAAAA...

Genetic variations in UGT2B28, UGT2B17, UGT2B15 genes and the risk of prostate cancer: A case-control study.

PubMed

Habibi, Mohsen; Mirfakhraie, Reza; Khani, Maryam; Rakhshan, Azadeh; Azargashb, Eznollah; Pouresmaeili, Farkhondeh

2017-11-15

Glucuronidation is a major pathway for elimination of exogenous and endogenous compounds such as environmental carcinogens and androgens from the body. This biochemical pathway is mediated by enzymes called uridine diphosphoglucuronosyltransferases (UGTs). Null (del/del) genes polymorphisms in UGT2B17, and UGT2B28 and D85Y single-nucleotide polymorphism (SNP) of UGT2B15 have been reported to increase the risk of prostate cancer. The goal of this study was to determine the association of mentioned genetic variants with the risk of prostate cancer. We investigated the copy number variations (CNVs) of UGT2B17 and UGT2B28 loci and the association between rs1902023 polymorphism of UGT2B15 gene in 360 subjects consisted of 120 healthy controls, 120 prostate cancer (PC) patients and 120 benign prostatic hyperplasia (BPH) patients. No association was detected for the mentioned polymorphisms and the risk of PC. However, a significant association was detected between UGT2B17 copy number variation and BPH risk (OR=2.189; 95% CI, 1.303-3.675; p=0.003). Furthermore, we observed that the D85Y polymorphism increases the risk of BPH when analyzed in combination with the copy number variation of UGT2B17 gene (OR=0.135; 95% CI, 0.036-0.512; p=0.003). Our findings suggest that the D85Y polymorphism of UGT2B15 and CNVs in UGT2B28 and UGT2B17 genes is not associated with prostate cancer risk in Iranian patients. To our knowledge, this is the first report that implicates the role of CNV of UGT2B17 gene in BPH. Copyright © 2017 Elsevier B.V. All rights reserved.

40 CFR Table 2b to Subpart Ce of... - Emissions Limits for Small HMIWI Which Meet the Criteria Under § 60.33e(b)(2)

Code of Federal Regulations, 2010 CFR

2010-07-01

... sample time per run) EPA Reference Method 10 or 10B of appendix A-4 of part 60. Dioxins/furans ng/dscm total dioxins/furans (gr/109 dscf) or ng/dscm TEQ (gr/109 dscf) 240 (100) or 5.1 (2.2) 3-run average (4...

40 CFR Table 2c to Subpart E of... - Reactivity Factors for Aromatic Hydrocarbon Solvent Mixtures

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 6 2014-07-01 2014-07-01 false Reactivity Factors for Aromatic Hydrocarbon Solvent Mixtures 2C Table 2C to Subpart E of Part 59 Protection of Environment ENVIRONMENTAL... Coatings Pt. 59, Subpt. E, Table 2C Table 2C to Subpart E of Part 59—Reactivity Factors for Aromatic...

40 CFR Table 2c to Subpart E of... - Reactivity Factors for Aromatic Hydrocarbon Solvent Mixtures

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 6 2013-07-01 2013-07-01 false Reactivity Factors for Aromatic Hydrocarbon Solvent Mixtures 2C Table 2C to Subpart E of Part 59 Protection of Environment ENVIRONMENTAL... Coatings Pt. 59, Subpt. E, Table 2C Table 2C to Subpart E of Part 59—Reactivity Factors for Aromatic...

40 CFR Table 2c to Subpart E of... - Reactivity Factors for Aromatic Hydrocarbon Solvent Mixtures

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 6 2012-07-01 2012-07-01 false Reactivity Factors for Aromatic Hydrocarbon Solvent Mixtures 2C Table 2C to Subpart E of Part 59 Protection of Environment ENVIRONMENTAL... Coatings Pt. 59, Subpt. E, Table 2C Table 2C to Subpart E of Part 59—Reactivity Factors for Aromatic...

Conservation, expression, and knockdown of zebrafish plxnb2a and plxnb2b.

PubMed

Perälä, Nina; Peitsaro, Nina; Sundvik, Maria; Koivula, Henri; Sainio, Kirsi; Sariola, Hannu; Panula, Pertti; Immonen, Tiina

2010-10-01

In mice lacking Plexin B2, a receptor of the axon guidance molecules Semaphorin 4C and Semaphorin 4D, the closure of the neural tube and structural organization of the cerebellum are severely impaired. We cloned two Plexin B2 orthologs, plxnb2a and plxnb2b, in zebrafish, which is a widely used model for the development of the vertebrate central nervous system (CNS). The predicted proteins, Plexin B2a and Plexin B2b, contain all the conserved and functional domains of the plexin B-subfamily. During embryonic development, plxnb2a is expressed, e.g., in pharyngeal arches while plxnb2b expression is more confined to neuronal structures like the cerebellum. However, both plxnb2a and plxnb2b are expressed at the midbrain-hindbrain boundary, in the otic vesicles, facial ganglia, and pectoral fins. Knockdown of both plxnb2a and plxnb2b simultaneously (>95% and 45%, respectively) resulted in normal CNS structure, axon guidance and swimming performance of the morphants.

High-pressure behavior of A 2 B 2 O 7 pyrochlore (A=Eu, Dy; B=Ti, Zr)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rittman, Dylan R.; Turner, Katlyn M.; Park, Sulgiye

2017-01-28

In situ high-pressure X-ray diffraction and Raman spectroscopy were used to determine the influence of composition on the high-pressure behavior of A 2B 2O 7 pyrochlore (A=Eu, Dy; B=Ti, Zr) up to ~50GPa. Based on X-ray diffraction results, all compositions transformed to the high-pressure cotunnite structure. The B-site cation species had a larger effect on the transition pressure than the A-site cation species, with the onset of the phase transformation occurring at ~41 GPa for B=Ti and ~16 GPa B=Zr. However, the A-site cation affected the kinetics of the phase transformation, with the transformation for compositions with the smaller ionicmore » radii, i.e., A=Dy, proceeding faster than those with a larger ionic radii, i.e., A=Eu. These results were consistent with previous work in which the radius-ratio of the A- and B-site cations determined the energetics of disordering, and compositions with more similarly sized A- and B-site cations had a lower defect formation energy. Raman spectra revealed differences in the degree of short-range order of the different compositions. Due to the large phase fraction of cotunnite at high pressure for B=Zr compositions, Raman modes for cotunnite could be observed, with more modes recorded for A=Eu than A=Dy. These additional modes are attributed to increased short-to-medium range ordering in the initially pyrochlore structured Eu 2Zr 2O 7 as compared with the initially defect-fluorite structured Dy 2Zr 2O 7.« less

High-Resolution Synchrotron Infrared Spectroscopy of Thiophosgene: the νb{1}, νb{5}, 2νb{4}, and νb{2} + 2νb{6} bands

NASA Astrophysics Data System (ADS)

McKellar, Bob; Billinghurst, Brant E.

2015-06-01

Thiophosgene (Cl_2CS) is a favorite model system for studies of photophysics, vibrational dynamics, and intersystem interactions. But at high resolution its infrared spectrum is very congested due to hot bands and multiple isotopic species. Previously, we reported the first high resolution IR study of this molecule, analyzing the νb{2} (504 wn) and νb{4} (471 wn) fundamental bands. Here we continue, with analysis of the νb{1} (1139 wn) and νb{5} (820 wn) fundamentals for the two most abundant isotopologues, 35Cl2CS and 35Cl37ClCS, based on spectra with a resolution of about 0.001 wn obtained at the Canadian Light Source far-infrared beamline using synchrotron radiation and a Bruker IFS125 Fourier transform spectrometer. The νb{2} + νb{4} (942 wn) and νb{2} + 2νb{6} (1104 wn) bands are also studied here. But so far the νb{2} + νb{6} combination band (795 wn) resists analysis, as do the weak νb{3} (292.9 wn) and νb{6} (≈300? wn) fundamentals. A.R.W. McKellar, B.E.Billinghurst, J. Mol. Spectrosc. 260, 66 (2010).

Transplantation of A2 and A2B kidneys from deceased donors into B waiting list candidates increases their transplantation rate.

PubMed

Bryan, Christopher F; Nelson, Paul W; Shield, Charles F; Ross, Gilbert; Warady, Bradley; Murillo, Daniel; Winklhofer, Franz T

2004-01-01

Transplant centers in the Midwest Transplant Network began transplanting kidneys from A2 or A2B donors into blood group B and O patients in 1986. Since 1991, an OPTN/UNOS variance has permitted us to allocate these kidneys preferentially into B and O waiting list patients. With more than 10 years of experience we have noted the following: 1. Thirty-one percent more blood group B patients were transplanted by allocating them A2 or A2B kidneys from our deceased donors. 2. Ten-year graft survival for B recipients of an A2 or A2B kidney (72%) was equivalent to that for B recipients of a B kidney (69%). 3. Type B recipients of simultaneous pancreas-kidney transplants (n=4) also did well with A2 or A2B organs. 4. Non-A recipients were transplanted only when their anti-A IgG titer history was consistently low (< or =4). 5. Most (90%) blood group B patients had a low anti-A IgG titer history; whereas, only one-third of blood group O patients had a low titer history. 6. Neither ethnicity nor HLA class I sensitization level influenced the anti-A IgG titer history. 7. In an OPO with mostly (87%) white donors, nearly 20% of blood group A donors were A2. 8. Waiting time until transplantation was lower for B patients who received an A2 or A2B kidney than for those who received a B or O kidney. 9. Our OPO blood group B waiting list was reduced from 25 low PRA (<40%) B candidates in 1994 to 4 in July, 2004. 10. Blood group A candidates received 6.4% fewer transplants with our A2/A2B--> B allocation algorithm. 11. Minority patients were transplanted at the same rate when using the A2/A2B--> B allocation algorithm as when using the standard UNOS algorithm for allocating B and O kidneys--> B patients.

40 CFR Table 2a to Subpart Zzzz of... - Emission Limitations for New and Reconstructed 2SLB and Compression Ignition Stationary RICE >500...

Code of Federal Regulations, 2011 CFR

2011-07-01

... Reconstructed 2SLB and Compression Ignition Stationary RICE >500 HP and New and Reconstructed 4SLB Stationary RICE â¥250 HP Located at a Major Source of HAP Emissions 2a Table 2a to Subpart ZZZZ of Part 63... 2SLB and Compression Ignition Stationary RICE >500 HP and New and Reconstructed 4SLB Stationary RICE...

40 CFR Table 2a to Subpart Zzzz of... - Emission Limitations for New and Reconstructed 2SLB and Compression Ignition Stationary RICE >500...

Code of Federal Regulations, 2010 CFR

2010-07-01

... Reconstructed 2SLB and Compression Ignition Stationary RICE >500 HP and New and Reconstructed 4SLB Stationary RICE â¥250 HP Located at a Major Source of HAP Emissions 2a Table 2a to Subpart ZZZZ of Part 63... 2SLB and Compression Ignition Stationary RICE >500 HP and New and Reconstructed 4SLB Stationary RICE...

Elemental abundance analyses with DAO spectrograms: XXX. The middle B through early A stars ξ2 Ceti (B9 III), 21 Aquilae (B8 II-III), ι Aquilae (B5 III), and ι Delphini (A2V)

NASA Astrophysics Data System (ADS)

Adelman, S. J.; Westbrook, P. C.; Gulliver, A. F.

2010-04-01

This series of high quality elemental abundance analyses of mostly main-sequence band normal and peculiar B, A, and F stars defines their properties and provides data for the comparison with the analyses of somewhat similar stars and with theoretical predictions. Most use high dispersion and high S/N (≥ 200) spectrograms obtained with CCD detectors at the long camera of the Coudé spectrograph of the 1.22-m Dominion Astrophysical Observatory telescope. Here we reanalyze 21 Aql with better quality spectra and increase the number of stars consistently analyzed in the spectral range B5 to A2 by analyzing three new stars for this series. In the early A stars the normal and non-mCP stars have abundances with overlapping ranges. But more stars are needed especially in the B5 to B9 range. ξ2 Cet on average has a solar composition with a few abundances outside the solar range while both 21 Aql and ι Aql have abundances marginally less than solar. The abundances of ι Del are greater than solar with a few elements such as Ca being less than solar. It is an Am star. Table 3 is only available in electronic form at the CDS via http://cdsarc.u-strasbg.fr/ftp/cats/J/other/AN/331/378

High-pressure behavior of A 2 B 2 O 7 pyrochlore (A=Eu, Dy; B=Ti, Zr)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rittman, Dylan R.; Turner, Katlyn M.; Park, Sulgiye

2017-01-24

In situ high-pressure X-ray diffraction and Raman spectroscopy were used to determine the influence of composition on the high-pressure behavior of A 2B 2O 7 pyrochlore (A = Eu, Dy; B = Ti, Zr) up to ~50 GPa. Based on X-ray diffraction results, all compositions transformed to the high-pressure cotunnite structure. The B-site cation species had a larger effect on the transition pressure than the A-site cation species, with the onset of the phase transformation occurring at ~41 GPa for B = Ti and ~16 GPa B = Zr. But, the A-site cation affected the kinetics of the phase transformation,more » with the transformation for compositions with the smaller ionic radii, i.e., A = Dy, proceeding faster than those with a larger ionic radii, i.e., A = Eu. Our results were consistent with previous work in which the radius-ratio of the A- and B-site cations determined the energetics of disordering, and compositions with more similarly sized A- and B-site cations had a lower defect formation energy. Raman spectra revealed differences in the degree of short-range order of the different compositions. Due to the large phase fraction of cotunnite at high pressure for B = Zr compositions, Raman modes for cotunnite could be observed, with more modes recorded for A = Eu than A = Dy. These additional modes are attributed to increased short-to-medium range ordering in the initially pyrochlore structured Eu 2Zr 2O 7 as compared with the initially defect-fluorite structured Dy 2Zr 2O 7.« less

Vaccination of dogs with canine parvovirus type 2b (CPV-2b) induces neutralising antibody responses to CPV-2a and CPV-2c.

PubMed

Wilson, Stephen; Illambas, Joanna; Siedek, Elisabeth; Stirling, Catrina; Thomas, Anne; Plevová, Edita; Sture, Gordon; Salt, Jeremy

2014-09-22

Since the identification of canine parvovirus type 2, three variants have subsequently been observed differing from the historical CPV-2 and each other by 1-2 amino acids only. As a result there has been considerable research into differential diagnostics, with some researchers indicating there is a need for new vaccines containing different strains of CPV-2. In this study we investigated whether vaccination with a CPV-2b containing vaccine would induce cross-reactive antibody responses to the other CPV-2 variants. Two studies where dogs were vaccinated with a multivalent vaccine, subsequently challenged with CPV-2b and sera samples analysed are presented. Six week old pups with defined serological status were vaccinated twice, three weeks apart and challenged either 5 weeks (MDA override study) or one year after vaccination (duration of immunity study). Sera samples were collected before each vaccination and at periods throughout each study. In each study the antibody profiles were very similar; serological responses against CPV-2a, CPV-2b and CPV-2c were higher than those for CPV-2. Nevertheless, responses against CPV-2 were well above levels considered clinically protective. In each study dogs also showed a rapid increase in antibody titres following vaccination, reached a plateau following second vaccination with a slight decline to challenge after which rapid anamnestic responses were seen. Evaluation of the serological responses suggests vaccination with CPV-2b would cross-protect against CPV-2a and CPV-2c, as well as against CPV-2 which is now extinct in the field. In conclusion we have demonstrated that vaccination of minimum aged dogs with a multivalent vaccine containing the CPV-2b variant strain will induce serological responses which are cross-reactive against all currently circulating field strains, CPV-2a and CPV-2c, and the now extinct field strain CPV-2. Copyright © 2014 Elsevier Ltd. All rights reserved.

40 CFR Table 2 of Subpart Ppp of... - Applicability of General Provisions to Subpart PPP Affected Sources

Code of Federal Regulations, 2010 CFR

2010-07-01

... Subpart PPP Affected Sources 2 Table 2 of Subpart PPP of Part 63 Protection of Environment ENVIRONMENTAL... Polyether Polyols Production Pt. 63, Subpt. PPP, Table 2 Table 2 of Subpart PPP of Part 63—Applicability of General Provisions to Subpart PPP Affected Sources Reference Applies to subpart PPP Explanation Applicable...

40 CFR Table 2 of Subpart Ppp of... - Applicability of General Provisions to Subpart PPP Affected Sources

Code of Federal Regulations, 2012 CFR

2012-07-01

... Subpart PPP Affected Sources 2 Table 2 of Subpart PPP of Part 63 Protection of Environment ENVIRONMENTAL... Polyether Polyols Production Pt. 63, Subpt. PPP, Table 2 Table 2 of Subpart PPP of Part 63—Applicability of General Provisions to Subpart PPP Affected Sources Reference Applies to subpart PPP Explanation Applicable...

40 CFR Table 2 of Subpart Ppp of... - Applicability of General Provisions to Subpart PPP Affected Sources

Code of Federal Regulations, 2011 CFR

2011-07-01

... Subpart PPP Affected Sources 2 Table 2 of Subpart PPP of Part 63 Protection of Environment ENVIRONMENTAL... Polyether Polyols Production Pt. 63, Subpt. PPP, Table 2 Table 2 of Subpart PPP of Part 63—Applicability of General Provisions to Subpart PPP Affected Sources Reference Applies to subpart PPP Explanation Applicable...

40 CFR Table 2 to Subpart Ll of... - Potline POM Limits for Emission Averaging

Code of Federal Regulations, 2011 CFR

2011-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Primary Aluminum Reduction Plants Pt. 63, Subpt. LL, Table 2 Table 2 to Subpart LL of Part 63—Potline POM Limits for Emission...

40 CFR Table 2 to Subpart Ll of... - Potline POM Limits for Emission Averaging

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Primary Aluminum Reduction Plants Pt. 63, Subpt. LL, Table 2 Table 2 to Subpart LL of Part 63—Potline POM Limits for Emission...

40 CFR Table 2 to Subpart Ll of... - Potline POM Limits for Emission Averaging

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Primary Aluminum Reduction Plants Pt. 63, Subpt. LL, Table 2 Table 2 to Subpart LL of Part 63—Potline POM Limits for Emission...

40 CFR Table 2 to Subpart Ll of... - Potline POM Limits for Emission Averaging

Code of Federal Regulations, 2012 CFR

2012-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Primary Aluminum Reduction Plants Pt. 63, Subpt. LL, Table 2 Table 2 to Subpart LL of Part 63—Potline POM Limits for Emission...

40 CFR Table 2 to Subpart V of... - Surge Control Vessels and Bottoms Receivers at New Sources

Code of Federal Regulations, 2013 CFR

2013-07-01

... Receivers at New Sources 2 Table 2 to Subpart V of Part 61 Protection of Environment ENVIRONMENTAL... POLLUTANTS National Emission Standard for Equipment Leaks (Fugitive Emission Sources) Pt. 61, Subpt. V, Table 2 Table 2 to Subpart V of Part 61—Surge Control Vessels and Bottoms Receivers at New Sources Vessel...

40 CFR Table 2 to Subpart V of... - Surge Control Vessels and Bottoms Receivers at New Sources

Code of Federal Regulations, 2014 CFR

2014-07-01

... Receivers at New Sources 2 Table 2 to Subpart V of Part 61 Protection of Environment ENVIRONMENTAL... POLLUTANTS National Emission Standard for Equipment Leaks (Fugitive Emission Sources) Pt. 61, Subpt. V, Table 2 Table 2 to Subpart V of Part 61—Surge Control Vessels and Bottoms Receivers at New Sources Vessel...

40 CFR Table 2 to Subpart V of... - Surge Control Vessels and Bottoms Receivers at New Sources

Code of Federal Regulations, 2012 CFR

2012-07-01

... Receivers at New Sources 2 Table 2 to Subpart V of Part 61 Protection of Environment ENVIRONMENTAL... POLLUTANTS National Emission Standard for Equipment Leaks (Fugitive Emission Sources) Pt. 61, Subpt. V, Table 2 Table 2 to Subpart V of Part 61—Surge Control Vessels and Bottoms Receivers at New Sources Vessel...

40 CFR Table 2 to Subpart V of... - Surge Control Vessels and Bottoms Receivers at New Sources

Code of Federal Regulations, 2010 CFR

2010-07-01

... Receivers at New Sources 2 Table 2 to Subpart V of Part 61 Protection of Environment ENVIRONMENTAL... POLLUTANTS National Emission Standard for Equipment Leaks (Fugitive Emission Sources) Pt. 61, Subpt. V, Table 2 Table 2 to Subpart V of Part 61—Surge Control Vessels and Bottoms Receivers at New Sources Vessel...

40 CFR Table 2 to Subpart V of... - Surge Control Vessels and Bottoms Receivers at New Sources

Code of Federal Regulations, 2011 CFR

2011-07-01

... Receivers at New Sources 2 Table 2 to Subpart V of Part 61 Protection of Environment ENVIRONMENTAL... POLLUTANTS National Emission Standard for Equipment Leaks (Fugitive Emission Sources) Pt. 61, Subpt. V, Table 2 Table 2 to Subpart V of Part 61—Surge Control Vessels and Bottoms Receivers at New Sources Vessel...

40 CFR Table 2 of Subpart Ppp of... - Applicability of General Provisions to Subpart PPP Affected Sources

Code of Federal Regulations, 2013 CFR

2013-07-01

... Subpart PPP Affected Sources 2 Table 2 of Subpart PPP of Part 63 Protection of Environment ENVIRONMENTAL... Emissions for Polyether Polyols Production Pt. 63, Subpt. PPP, Table 2 Table 2 of Subpart PPP of Part 63—Applicability of General Provisions to Subpart PPP Affected Sources Reference Applies to subpart PPP Explanation...

40 CFR Table 2 of Subpart Ppp of... - Applicability of HON Provisions to Subpart PPP Affected Sources

Code of Federal Regulations, 2014 CFR

2014-07-01

... Subpart PPP Affected Sources 2 Table 2 of Subpart PPP of Part 63 Protection of Environment ENVIRONMENTAL... Emissions for Polyether Polyols Production Pt. 63, Subpt. PPP, Table 2 Table 2 of Subpart PPP of Part 63—Applicability of HON Provisions to Subpart PPP Affected Sources Reference Applies to subpart PPP Explanation...

INSAT-2A and 2B development mechanisms

NASA Technical Reports Server (NTRS)

Sathyanarayan, M. N.; Rao, M. Nageswara; Nataraju, B. S.; Viswanatha, N.; Chary, M. Laxmana; Balan, K. S.; Murthy, V. Sridhara; Aller, Raju; Kumar, H. N. Suresha

1994-01-01

The Indian National Satellite (INSAT) 2A and 2B have deployment mechanisms for deploying the solar array, two C/S band antenna reflectors and a coilable lattice boom with sail. The mechanisms have worked flawlessly on both satellites. The configuration details, precautions taken during the design phase, the test philosophy, and some of the critical analysis activities are discussed.

40 CFR Table 2 to Subpart H of... - Surge Control Vessels and Bottoms Receivers at Existing Sources

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 9 2010-07-01 2010-07-01 false Surge Control Vessels and Bottoms Receivers at Existing Sources 2 Table 2 to Subpart H of Part 63 Protection of Environment ENVIRONMENTAL... Equipment Leaks Pt. 63, Subpt. H, Table 2 Table 2 to Subpart H of Part 63—Surge Control Vessels and Bottoms...

40 CFR Table 2 to Subpart Fff of... - Nitrogen Oxides Requirements for Affected Facilities

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 8 2011-07-01 2011-07-01 false Nitrogen Oxides Requirements for... Before September 20, 1994 Pt. 62, Subpt. FFF, Table 2 Table 2 to Subpart FFF of Part 62—Nitrogen Oxides Requirements for Affected Facilities Municipal waste combustor technology Nitrogen oxides emission limit (parts...

40 CFR Table 2 to Subpart Fff of... - Nitrogen Oxides Requirements for Affected Facilities

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 9 2014-07-01 2014-07-01 false Nitrogen Oxides Requirements for... Before September 20, 1994 Pt. 62, Subpt. FFF, Table 2 Table 2 to Subpart FFF of Part 62—Nitrogen Oxides Requirements for Affected Facilities Municipal waste combustor technology Nitrogen oxides emission limit (parts...

40 CFR Table 2 to Subpart Fff of... - Nitrogen Oxides Requirements for Affected Facilities

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 9 2012-07-01 2012-07-01 false Nitrogen Oxides Requirements for... Before September 20, 1994 Pt. 62, Subpt. FFF, Table 2 Table 2 to Subpart FFF of Part 62—Nitrogen Oxides Requirements for Affected Facilities Municipal waste combustor technology Nitrogen oxides emission limit (parts...

40 CFR Table 2 to Subpart Fff of... - Nitrogen Oxides Requirements for Affected Facilities

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 9 2013-07-01 2013-07-01 false Nitrogen Oxides Requirements for... Before September 20, 1994 Pt. 62, Subpt. FFF, Table 2 Table 2 to Subpart FFF of Part 62—Nitrogen Oxides Requirements for Affected Facilities Municipal waste combustor technology Nitrogen oxides emission limit (parts...

Rf2a and rf2b transcription factors

DOEpatents

Beachy, Roger N.; Petruccelli, Silvana; Dai, Shunhong

2007-10-02

A method of activating the rice tungro bacilliform virus (RTBV) promoter in vivo is disclosed. The RTBV promoter is activated by exposure to at least one protein selected from the group consisting of Rf2a and Rf2b.

Identification of UGT2B9*2 and UGT2B33 isolated from female rhesus monkey liver.

PubMed

Dean, Brian; Arison, Byron; Chang, Steve; Thomas, Paul E; King, Christopher

2004-06-01

Two UDP-glucuronosyltransferases (UGT2B9(*)2 and UGT2B33) have been isolated from female rhesus monkey liver. Microsomal preparations of the cell lines expressing the UGTs catalyzed the glucuronidation of the general substrate 7-hydroxy-4-(trifluoromethyl)coumarin in addition to selected estrogens (beta-estradiol and estriol) and opioids (morphine, naloxone, and naltrexone). UGT2B9(*)2 displayed highest efficiency for beta-estradiol-17-glucuronide production and did not catalyze the glucuronidation of naltrexone. UGT2B33 displayed highest efficiency for estriol and did not catalyze the glucuronidation of beta-estradiol. UGT2B9(*)2 was found also to catalyze the glucuronidation of 4-hydroxyestrone, 16-epiestriol, and hyodeoxycholic acid, while UGT2B33 was capable of conjugating 4-hydroxyestrone, androsterone, diclofenac, and hyodeoxycholic acid. Three glucocorticoids (cortisone, cortisol, and corticosterone) were not substrates for glucuronidation by liver or kidney microsomes or any expressed UGTs. Our current data suggest the use of beta-estradiol-3-glucuronidation, beta-estradiol-17-glucuronidation, and estriol-17-glucuronidation to assay UGT1A01, UGT2B9(*)2, and UGT2B33 activity in rhesus liver microsomes, respectively.

SMART-on-FHIR implemented over i2b2

PubMed Central

Mandel, Joshua C; Klann, Jeffery G; Wattanasin, Nich; Mendis, Michael; Chute, Christopher G; Mandl, Kenneth D; Murphy, Shawn N

2017-01-01

We have developed an interface to serve patient data from Informatics for Integrating Biology and the Bedside (i2b2) repositories in the Fast Healthcare Interoperability Resources (FHIR) format, referred to as a SMART-on-FHIR cell. The cell serves FHIR resources on a per-patient basis, and supports the “substitutable” modular third-party applications (SMART) OAuth2 specification for authorization of client applications. It is implemented as an i2b2 server plug-in, consisting of 6 modules: authentication, REST, i2b2-to-FHIR converter, resource enrichment, query engine, and cache. The source code is freely available as open source. We tested the cell by accessing resources from a test i2b2 installation, demonstrating that a SMART app can be launched from the cell that accesses patient data stored in i2b2. We successfully retrieved demographics, medications, labs, and diagnoses for test patients. The SMART-on-FHIR cell will enable i2b2 sites to provide simplified but secure data access in FHIR format, and will spur innovation and interoperability. Further, it transforms i2b2 into an apps platform. PMID:27274012

On Association Coefficients for 2x2 Tables and Properties that Do Not Depend on the Marginal Distributions

ERIC Educational Resources Information Center

Warrens, Matthijs J.

2008-01-01

We discuss properties that association coefficients may have in general, e.g., zero value under statistical independence, and we examine coefficients for 2x2 tables with respect to these properties. Furthermore, we study a family of coefficients that are linear transformations of the observed proportion of agreement given the marginal…

40 CFR Table C-4 to Subpart C of... - Test Specifications for PM10, PM2.5 and PM10-2.5 Candidate Equivalent Methods

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 5 2011-07-01 2011-07-01 false Test Specifications for PM10, PM2.5 and PM10-2.5 Candidate Equivalent Methods C Table C-4 to Subpart C of Part 53 Protection of Environment... Pt. 53, Subpt. C, Table C-4 Table C-4 to Subpart C of Part 53—Test Specifications for PM10, PM2.5 and...

40 CFR Table C-4 to Subpart C of... - Test Specifications for PM10, PM2.5 and PM10-2.5 Candidate Equivalent Methods

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 6 2012-07-01 2012-07-01 false Test Specifications for PM10, PM2.5 and PM10-2.5 Candidate Equivalent Methods C Table C-4 to Subpart C of Part 53 Protection of Environment... Pt. 53, Subpt. C, Table C-4 Table C-4 to Subpart C of Part 53—Test Specifications for PM10, PM2.5 and...

40 CFR Table C-4 to Subpart C of... - Test Specifications for PM10, PM2.5 and PM10-2.5 Candidate Equivalent Methods

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Test Specifications for PM10, PM2.5 and PM10-2.5 Candidate Equivalent Methods C Table C-4 to Subpart C of Part 53 Protection of Environment... Pt. 53, Subpt. C, Table C-4 Table C-4 to Subpart C of Part 53—Test Specifications for PM10, PM2.5 and...

Combustion synthesis of AlB2-Al2O3 composite powders with AlB2 nanowire structures

NASA Astrophysics Data System (ADS)

Yang, Pan; Xiao, Guoqing; Ding, Donghai; Ren, Yun; Yang, Shoulei; Lv, Lihua; Hou, Xing

2018-05-01

Using of Al and B2O3 powders as starting materials, and Mg-Al alloy as additives, AlB2-Al2O3 composite powders with AlB2 nanowire structures were successfully fabricated via combustion synthesis method in Ar atmosphere at a pressure of 1.5 MPa. The effect of different amount of Mg-Al alloy on the phase compositions and morphology of the combustion products was investigated. The results revealed that AlB2 and Al2O3 increased, whereas Al decreased with the content of Mg-Al alloy increasing. The impurities MgAl2O4 and AlB12 would exist in the sample with adding of 18 wt% Mg-Al alloy. Interestingly, FESEM/TEM/EDS results showed that AlB2 nanowires were observed in the products when the content of Mg-Al alloy is 6 wt% and 12 wt%. The more AlB2 nanowires can be found as the content of Mg-Al alloy increased. And the yield of AlB2 nanowires with the diameter of about 200 nanometers (nm) and the length up to several tens of micrometers (μm) in the combustion product is highest when the content of Mg-Al alloy is 12 wt%. The vapor, such as Mg-Al (g), B2O2 (g), AlO (g) and Al2O (g), produced during the process of combustion synthesis, reacted with each other to yield AlB2 nanowires by vapor-solid (VS) mechanism and the corresponding model was also proposed.

Grb2 regulates B-cell maturation, B-cell memory responses and inhibits B-cell Ca2+ signalling.

PubMed

Ackermann, Jochen A; Radtke, Daniel; Maurberger, Anna; Winkler, Thomas H; Nitschke, Lars

2011-04-20

Grb2 is a ubiquitously expressed adaptor protein, which activates Ras and MAP kinases in growth factor receptor signalling, while in B-cell receptor (BCR) signalling this role is controversial. In B cell lines it was shown that Grb2 can inhibit BCR-induced Ca(2+) signalling. Nonetheless, the physiological role of Grb2 in primary B cells is still unknown. We generated a B-cell-specific Grb2-deficient mouse line, which had a severe reduction of mature follicular B cells in the periphery due to a differentiation block and decreased B-cell survival. Moreover, we found several changes in important signalling pathways: enhanced BCR-induced Ca(2+) signalling, alterations in mitogen-activated protein kinase activation patterns and strongly impaired Akt activation, the latter pointing towards a defect in PI3K signalling. Interestingly, B-cell-specific Grb2-deficient mice showed impaired IgG and B-cell memory responses, and impaired germinal centre formation. Thus, Grb2-dependent signalling pathways are crucial for lymphocyte differentiation processes, as well as for control of secondary humoral immune responses.

40 CFR Table 2 to Subpart Wwww of... - Compliance Dates for New and Existing Reinforced Plastic Composites Facilities

Code of Federal Regulations, 2014 CFR

2014-07-01

... Reinforced Plastic Composites Facilities 2 Table 2 to Subpart WWWW of Part 63 Protection of Environment... Pollutants: Reinforced Plastic Composites Production Pt. 63, Subpt. WWWW, Table 2 Table 2 to Subpart WWWW of Part 63—Compliance Dates for New and Existing Reinforced Plastic Composites Facilities As required in...

40 CFR Table 2 to Subpart Wwww of... - Compliance Dates for New and Existing Reinforced Plastic Composites Facilities

Code of Federal Regulations, 2013 CFR

2013-07-01

... Reinforced Plastic Composites Facilities 2 Table 2 to Subpart WWWW of Part 63 Protection of Environment... Pollutants: Reinforced Plastic Composites Production Pt. 63, Subpt. WWWW, Table 2 Table 2 to Subpart WWWW of Part 63—Compliance Dates for New and Existing Reinforced Plastic Composites Facilities As required in...

40 CFR Table 2 to Subpart Wwww of... - Compliance Dates for New and Existing Reinforced Plastic Composites Facilities

Code of Federal Regulations, 2012 CFR

2012-07-01

... Reinforced Plastic Composites Facilities 2 Table 2 to Subpart WWWW of Part 63 Protection of Environment... Pollutants: Reinforced Plastic Composites Production Pt. 63, Subpt. WWWW, Table 2 Table 2 to Subpart WWWW of Part 63—Compliance Dates for New and Existing Reinforced Plastic Composites Facilities As required in...

40 CFR Table 2 to Subpart Dd of... - Applicability of Paragraphs in Subpart A of This Part 63-General Provisions to Subpart DD

Code of Federal Regulations, 2010 CFR

2010-07-01

... A of This Part 63-General Provisions to Subpart DD 2 Table 2 to Subpart DD of Part 63 Protection of... Hazardous Air Pollutants from Off-Site Waste and Recovery Operations Pt. 63, Subpt. DD, Table 2 Table 2 to Subpart DD of Part 63—Applicability of Paragraphs in Subpart A of This Part 63—General Provisions to...

QSAR analyses of conformationally restricted 1,5-diaryl pyrazoles as selective COX-2 inhibitors: application of connection table representation of ligands.

PubMed

Prasanna, S; Manivannan, E; Chaturvedi, S C

2005-04-15

As a part of our continuing efforts in discerning the structural and physicochemical requirements for selective COX-2 over COX-1 inhibition among the fused pyrazole ring systems, herein we report the QSAR analyses of the title compounds. The conformational flexibility of the title compounds was examined using a simple connection table representation. The conformational investigation was aided by calculating a connection table parameter called fraction of rotable bonds, b_rotR encompassing the number of rotable bonds and b_count, the number of bonds including implicit hydrogens of each ligand. The hydrophobic and steric correlation of the title compounds towards selective COX-2 inhibition was reported previously in one of our recent publications. In this communication, we attempt to calculate Wang-Ford charges of the non-hydrogen common atoms of AM1 optimized geometries of the title compounds. Owing to the partial conformational flexibility of title compounds, conformationally restricted and unrestricted descriptors were calculated from MOE. Correlation analysis of these 2D, 3D and Wang-Ford charges was accomplished by linear regression analysis. 2D molecular descriptor b_single, 3D molecular descriptors glob, std_dim3 showed significant contribution towards COX-2 inhibitory activity. Balaban J, a connectivity topological index showed a negative and positive contribution towards COX-1 and selective COX-2 over COX-1 inhibition, respectively. Wang-Ford charges calculated on C(7) showed a significant contribution towards COX-1 inhibitory activity whereas charges calculated on C(8) were crucial in governing the selectivity of COX-2 over COX-1 inhibition among these congeners.

40 CFR Table 2 to Subpart Wwww of... - Compliance Dates for New and Existing Reinforced Plastic Composites Facilities

Code of Federal Regulations, 2011 CFR

2011-07-01

... Reinforced Plastic Composites Facilities 2 Table 2 to Subpart WWWW of Part 63 Protection of Environment...: Reinforced Plastic Composites Production Pt. 63, Subpt. WWWW, Table 2 Table 2 to Subpart WWWW of Part 63—Compliance Dates for New and Existing Reinforced Plastic Composites Facilities As required in §§ 63.5800 and...

40 CFR Table 2 to Subpart Wwww of... - Compliance Dates for New and Existing Reinforced Plastic Composites Facilities

Code of Federal Regulations, 2010 CFR

2010-07-01

... Reinforced Plastic Composites Facilities 2 Table 2 to Subpart WWWW of Part 63 Protection of Environment...: Reinforced Plastic Composites Production Pt. 63, Subpt. WWWW, Table 2 Table 2 to Subpart WWWW of Part 63—Compliance Dates for New and Existing Reinforced Plastic Composites Facilities As required in §§ 63.5800 and...

Targeted Segment Transfer from Rye Chromosome 2R to Wheat Chromosomes 2A, 2B, and 7B.

PubMed

Ren, Tianheng; Li, Zhi; Yan, Benju; Tan, Feiquan; Tang, Zongxiang; Fu, Shulan; Yang, Manyu; Ren, Zhenglong

2017-01-01

Increased chromosome instability was induced by a rye (Secale cereale L.) monosomic 2R chromosome into wheat (Triticum aestivum L.). Centromere breakage and telomere dysfunction result in high rates of chromosome aberrations, including breakages, fissions, fusions, deletions, and translocations. Plants with target traits were sequentially selected to produce a breeding population, from which 3 translocation lines with target traits have been selected. In these lines, wheat chromosomes 2A, 2B, and 7B recombined with segments of the rye chromosome arm 2RL. This was detected by FISH analysis using repeat sequences pSc119.2, pAs1 and genomic DNA of rye together as probes. The translocation chromosomes in these lines were named as 2ASMR, 2BSMR, and 7BSMR. The small segments that were transferred into wheat consisted of pSc119.2 repeats and other chromatin regions that conferred resistance to stripe rust and expressed target traits. These translocation lines were highly resistant to stripe rust, and expressed several typical traits that were associated with chromosome arm 2RL, which are better than those of its wheat parent, disomic addition, and substitution lines that show agronomic characteristics. The integration of molecular methods and conventional techniques to improve wheat breeding schemes are discussed. © 2017 S. Karger AG, Basel.

46 CFR 160.050-2 - Types and sizes.

Code of Federal Regulations, 2012 CFR

2012-10-01

... a plus or minus 5 percent will be allowable on the dimensions indicated in Table 160.050-2(b). Table 160.050-2(b)—Sizes and Dimensions of Ring Life Buoys Size Dimensions (inches) Finished ring 30-inch 30...

46 CFR 160.050-2 - Types and sizes.

Code of Federal Regulations, 2013 CFR

2013-10-01

... a plus or minus 5 percent will be allowable on the dimensions indicated in Table 160.050-2(b). Table 160.050-2(b)—Sizes and Dimensions of Ring Life Buoys Size Dimensions (inches) Finished ring 30-inch 30...

46 CFR 160.050-2 - Types and sizes.

Code of Federal Regulations, 2010 CFR

2010-10-01

... a plus or minus 5 percent will be allowable on the dimensions indicated in Table 160.050-2(b). Table 160.050-2(b)—Sizes and Dimensions of Ring Life Buoys Size Dimensions (inches) Finished ring 30-inch 30...

46 CFR 160.050-2 - Types and sizes.

Code of Federal Regulations, 2014 CFR

2014-10-01

... a plus or minus 5 percent will be allowable on the dimensions indicated in Table 160.050-2(b). Table 160.050-2(b)—Sizes and Dimensions of Ring Life Buoys Size Dimensions (inches) Finished ring 30-inch 30...

46 CFR 160.050-2 - Types and sizes.

Code of Federal Regulations, 2011 CFR

2011-10-01

... a plus or minus 5 percent will be allowable on the dimensions indicated in Table 160.050-2(b). Table 160.050-2(b)—Sizes and Dimensions of Ring Life Buoys Size Dimensions (inches) Finished ring 30-inch 30...

40 CFR Table 2 to Subpart Uuu of... - Operating Limits for Metal HAP Emissions From Catalytic Cracking Units

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 13 2014-07-01 2014-07-01 false Operating Limits for Metal HAP Emissions From Catalytic Cracking Units 2 Table 2 to Subpart UUU of Part 63 Protection of Environment... Units Pt. 63, Subpt. UUU, Table 2 Table 2 to Subpart UUU of Part 63—Operating Limits for Metal HAP...

40 CFR Table 2 to Subpart Uuu of... - Operating Limits for Metal HAP Emissions From Catalytic Cracking Units

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 13 2012-07-01 2012-07-01 false Operating Limits for Metal HAP Emissions From Catalytic Cracking Units 2 Table 2 to Subpart UUU of Part 63 Protection of Environment... Units Pt. 63, Subpt. UUU, Table 2 Table 2 to Subpart UUU of Part 63—Operating Limits for Metal HAP...

40 CFR Table 2 to Subpart Uuu of... - Operating Limits for Metal HAP Emissions From Catalytic Cracking Units

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 13 2013-07-01 2012-07-01 true Operating Limits for Metal HAP Emissions From Catalytic Cracking Units 2 Table 2 to Subpart UUU of Part 63 Protection of Environment... Units Pt. 63, Subpt. UUU, Table 2 Table 2 to Subpart UUU of Part 63—Operating Limits for Metal HAP...

Determination of the Rate Constants for the NH 2 (X 2 B 1 ) + NH 2 (X 2 B 1 ) and NH 2 (X 2 B 1 ) + H Recombination Reactions in N 2 as a Function of Temperature and Pressure

DOE Office of Scientific and Technical Information (OSTI.GOV)

Altinay, Gokhan; Macdonald, R. Glen

2015-07-16

The recombination rate constants for the reactions NH2 + NH2 → N2H4 (reaction k1b) and NH2 + H → NH3 (reaction k2b) with N2 as a third-body have been measured as a function of temperature and pressure. The temperature range was from 292 to 533 K and the pressure range from a few Torr up to 300–400 Torr, well within the pressure falloff region. The NH2 radical was produced by 193 nm pulsed-laser photolysis of NH3 in a temperature controlled flow chamber. High-resolution time-resolved laser absorption spectroscopy was used to follow the temporal concentration profiles of both NH2 and NH3, simultaneously. The NH2 radical was monitored at 14800.65 cm–1 using the 1231 (0,7,0)Ã2A1 ← 1331 (0,0,0)more » $$\\tilde{X}$$2B1 ro-vibronic transition, and NH3 monitored at 3336.39 cm–1 on the qQ3(3)s (1,0,0,0) ← (0,0,0,0) ro-vibrational transition. The necessary collisional broadening parameters for each molecule were measured in separate experiments. The pressure and temperature dependence of k1b can be represented by the Troe parameters: k0, the low-pressure three-body recombination rate constant, k0(T) = (1.14 ± 0.59) × 10–19T–(3.41±0.28) cm6 molecule–2 s–1, and Fcent, the pressure broadening parameter, Fcent = 0.15 ± 0.12, independent of temperature. The data could not be fit by three-independent parameters, and the high-pressure limiting rate constant k∞(T) = 9.33 × 10–10T–0.414 e33/T cm3 molecule–1 s–1 was taken from the high-quality theoretical calculations of Klippenstein et al. (J. Phys. Chem A 2009, 113, 10241). The pressure and temperature dependence of k2b, can be represented by the Troe parameters: k0(T) = (9.95 ± 0.58) × 10–26T(-1.76±0.092) cm6 molecule–2 s–1, Fcent = 0.5 ± 0.2, k∞ = 2.6 × 10–10 cm3 molecule–1 s–1. Again, the data could not be fit with three independent parameters, and k2b∞ was chosen to be 2.6 × 10–10 cm3 molecule–1 s–1 and fixed in the analysis.« less

Synthesis, Structure, Bonding, and Reactivity of Metal Complexes Comprising Diborane(4) and Diborene(2): [{Cp*Mo(CO)2 }2 {μ-η2 :η2 -B2 H4 }] and [{Cp*M(CO)2 }2 B2 H2 M(CO)4 ], M=Mo,W.

PubMed

Mondal, Bijan; Bag, Ranjit; Ghorai, Sagar; Bakthavachalam, K; Jemmis, Eluvathingal D; Ghosh, Sundargopal

2018-07-02

The reaction of [(Cp*Mo) 2 (μ-Cl) 2 B 2 H 6 ] (1) with CO at room temperature led to the formation of the highly fluxional species [{Cp*Mo(CO) 2 } 2 {μ-η 2 :η 2 -B 2 H 4 }] (2). Compound 2, to the best of our knowledge, is the first example of a bimetallic diborane(4) conforming to a singly bridged C s structure. Theoretical studies show that 2 mimics the Cotton dimolybdenum-alkyne complex [{CpMo(CO) 2 } 2 C 2 H 2 ]. In an attempt to replace two hydrogen atoms of diborane(4) in 2 with a 2e [W(CO) 4 ] fragment, [{Cp*Mo(CO) 2 } 2 B 2 H 2 W(CO) 4 ] (3) was isolated upon treatment with [W(CO) 5 ⋅thf]. Compound 3 shows the intriguing presence of [B 2 H 2 ] with a short B-B length of 1.624(4) Å. We isolated the tungsten analogues of 3, [{Cp*W(CO) 2 } 2 B 2 H 2 W(CO) 4 ] (4) and [{Cp*W(CO) 2 } 2 B 2 H 2 Mo(CO) 4 ] (5), which provided direct proof of the existence of the tungsten analogue of 2. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Scratch Testing of Hot-Pressed Monolithic Chromium Diboride (CrB2) and CrB2 + MoSi2 Composite

NASA Astrophysics Data System (ADS)

Bhatt, B.; Murthy, T. S. R. Ch.; Singh, K.; Sashanka, A.; Vishwanadh, B.; Sonber, J. K.; Sairam, K.; Nageswara Rao, G. V. S.; Srinivasa Rao, T.; Kain, Vivekanand

2017-10-01

The tribological performance of hot-pressed monolithic CrB2 and a newly developed CrB2 + 20 vol.% MoSi2 composite was investigated by using scratch test. The test was carried out under progressive loading ranging from 0.9 to 30 N over a scratch distance of 3 mm. In situ values of coefficient of friction (COF), depth of penetration and acoustic emission were recorded. The wear volume and fracture toughness were also calculated. COF of both materials is increased with increasing the scratch length and progressive load. COF of the composite was observed to be slightly higher compared to the monolithic CrB2. The wear volume of the composite is 60% higher compared to monolithic CrB2. Fracture toughness values of 2.48 and 2.81 MPa m1/2 were calculated for monolithic CrB2 and CrB2 + 20 vol.% MoSi2 composite, respectively. Microstructural characterization indicates that the abrasive wear is the dominant wear mechanism in both the materials.

40 CFR Table Aa-1 to Subpart Aa of... - Kraft Pulping Liquor Emissions Factors for Biomass-Based CO2, CH4, and N2O

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Kraft Pulping Liquor Emissions Factors for Biomass-Based CO2, CH4, and N2O AA Table AA-1 to Subpart AA of Part 98 Protection of Environment... Paper Manufacturing Pt. 98, Subpt. AA, Table AA-1 Table AA-1 to Subpart AA of Part 98—Kraft Pulping...

40 CFR Table Aa-1 to Subpart Aa of... - Kraft Pulping Liquor Emissions Factors for Biomass-Based CO2, CH4, and N2O

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Kraft Pulping Liquor Emissions Factors for Biomass-Based CO2, CH4, and N2O AA Table AA-1 to Subpart AA of Part 98 Protection of Environment... Paper Manufacturing Pt. 98, Subpt. AA, Table AA-1 Table AA-1 to Subpart AA of Part 98—Kraft Pulping...

40 CFR Table Aa-1 to Subpart Aa of... - Kraft Pulping Liquor Emissions Factors for Biomass-Based CO2, CH4, and N2O

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Kraft Pulping Liquor Emissions Factors for Biomass-Based CO2, CH4, and N2O AA Table AA-1 to Subpart AA of Part 98 Protection of Environment... Paper Manufacturing Pt. 98, Subpt. AA, Table AA-1 Table AA-1 to Subpart AA of Part 98—Kraft Pulping...

40 CFR Table Aa-1 to Subpart Aa of... - Kraft Pulping Liquor Emissions Factors for Biomass-Based CO2, CH4, and N2O

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Kraft Pulping Liquor Emissions Factors for Biomass-Based CO2, CH4, and N2O AA Table AA-1 to Subpart AA of Part 98 Protection of Environment... Paper Manufacturing Pt. 98, Subpt. AA, Table AA-1 Table AA-1 to Subpart AA of Part 98—Kraft Pulping...

40 CFR Table C-4 to Subpart C of... - Test Specifications for PM 10, PM 2.5 and PM 10-2.5 Candidate Equivalent Methods

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 6 2014-07-01 2014-07-01 false Test Specifications for PM 10, PM 2.5 and PM 10-2.5 Candidate Equivalent Methods C Table C-4 to Subpart C of Part 53 Protection of... Reference Methods Pt. 53, Subpt. C, Table C-4 Table C-4 to Subpart C of Part 53—Test Specifications for PM...

40 CFR Table C-4 to Subpart C of... - Test Specifications for PM 10, PM 2.5 and PM 10-2.5 Candidate Equivalent Methods

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 6 2013-07-01 2013-07-01 false Test Specifications for PM 10, PM 2.5 and PM 10-2.5 Candidate Equivalent Methods C Table C-4 to Subpart C of Part 53 Protection of... Reference Methods Pt. 53, Subpt. C, Table C-4 Table C-4 to Subpart C of Part 53—Test Specifications for PM...

76 FR 9515 - Airworthiness Directives; Turbomeca S.A. ARRIEL 2B and 2B1 Turboshaft Engines

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-18

.... ARRIEL 2B and 2B1 Turboshaft Engines AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice... (GG) Turbine Blade rupture occurred in service on ARRIEL 2 twin engine applications and recently one on a single engine helicopter. For the case occurring in flight on a single engine helicopter (ARRIEL...

Structure investigation of maltacine B1a, B1b, B2a and B2b: cyclic peptide lactones of the maltacine complex from Bacillus subtilis.

PubMed

Hagelin, Gunnar

2005-04-01

A new complex of cyclic peptide lactone antibiotics from Bacillus subtilis, which we named maltacines, has recently been described. The structure elucidation of four of them is reported in this paper. The amino acid sequences and structures of the peptides were found by MSn of the ring-opened linear peptides that gave uninterrupted sequences of Bn and Y''n ions. The identities of three unknown residues in the sequences were solved by a combination of derivatization with phenyl isothiocyanate (PITC), high-resolution mass spectrometry and H/D exchange. The nature and position of the cyclic structure were revealed by a chemoselective ring opening with Na18OH and was found to be a lactone formed between a hydroxyl of residue number 4 and the C-terminal amino acid number 12. For verification of the structure of the B2+ ion, peptides with different combinations of P/Q and P/K at the N-terminus were synthesized. The structures of the four peptides were found to be as follows: B1a/B2a, cyclo-4,12(P-Q-Y-HNLeu-A-E-T-Y-Orn-103-Y-I-OH); and B1b/B2b, cyclo-4,12(P-Q-Y-HNLeu-A-E-T-Y-K-103-Y-I-OH). Copyright 2005 John Wiley & Sons, Ltd.

Enhanced expression of rat hepatic CYP2B1/2B2 and 2E1 by pyridine: differential induction kinetics and molecular basis of expression.

PubMed

Kim, H; Putt, D; Reddy, S; Hollenberg, P F; Novak, R F

1993-11-01

Expression of the cytochrome P450 (CYP) 2B subfamily in rat and rabbit hepatic tissues after pyridine (PY) treatment has been examined, and the molecular basis for enhanced 2B1/2B2 expression has been determined. P450 expression was monitored using metabolic activity, sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunoblot analyses, and the identity of the proteins was confirmed through N-terminus microsequence analysis. PY caused a dose-dependent elevation of hepatic CYP2B1/B2B levels in rats, which ranged from 4- to 22-fold over the dosing regimen of 100 to 400 mg PY/kg/day, for 3 days, respectively. PY at low dose failed to induce CYP2B in rabbit hepatic tissue, suggesting a species-dependent response in 2B expression. Anti-2B1 IgG addition to PY-induced microsomes inhibited benzphetamine N-demethylase activity by only approximately 15%, in sharp contrast to the approximately 73% inhibition observed for phenobarbital-induced microsomes, suggesting the induction of other form(s) of P450 having benzphetamine N-demethylase activity. Northern blot analysis revealed that PY treatment increased 2B1 and 2B2 poly(A)+ RNA levels approximately 69- and approximately 34-fold, respectively, whereas the 2E1 poly(A)+ RNA levels failed to increase. The results of this study show that PY induces CYP2B1/2B2 and that induction is species-dependent and kinetically distinguishable from 2E1 induction. Moreover, 2B1/2B2 induction occurs as a result of elevated mRNA levels associated with either transcriptional activation or mRNA stabilization, and it differs from the mechanism of hepatic 2E1 induction by PY.

40 CFR Table 2 to Subpart Cccccc... - Applicability Criteria and Management Practices for Gasoline Cargo Tanks Unloading at Gasoline...

Code of Federal Regulations, 2011 CFR

2011-07-01

... Practices for Gasoline Cargo Tanks Unloading at Gasoline Dispensing Facilities With Monthly Throughput of 100,000 Gallons of Gasoline or More 2 Table 2 to Subpart CCCCCC of Part 63 Protection of Environment... Pollutants for Source Category: Gasoline Dispensing Facilities Pt. 63, Subpt. CCCCCC, Table 2 Table 2 to...

40 CFR Table 2 to Subpart Cccccc... - Applicability Criteria and Management Practices for Gasoline Cargo Tanks Unloading at Gasoline...

Code of Federal Regulations, 2013 CFR

2013-07-01

... Practices for Gasoline Cargo Tanks Unloading at Gasoline Dispensing Facilities With Monthly Throughput of 100,000 Gallons of Gasoline or More 2 Table 2 to Subpart CCCCCC of Part 63 Protection of Environment... Pollutants for Source Category: Gasoline Dispensing Facilities Pt. 63, Subpt. CCCCCC, Table 2 Table 2 to...

40 CFR Table 2 to Subpart Cccccc... - Applicability Criteria and Management Practices for Gasoline Cargo Tanks Unloading at Gasoline...

Code of Federal Regulations, 2010 CFR

2010-07-01

... Practices for Gasoline Cargo Tanks Unloading at Gasoline Dispensing Facilities With Monthly Throughput of 100,000 Gallons of Gasoline or More 2 Table 2 to Subpart CCCCCC of Part 63 Protection of Environment... Pollutants for Source Category: Gasoline Dispensing Facilities Pt. 63, Subpt. CCCCCC, Table 2 Table 2 to...

40 CFR Table 2 to Subpart Cccccc... - Applicability Criteria and Management Practices for Gasoline Cargo Tanks Unloading at Gasoline...

Code of Federal Regulations, 2014 CFR

2014-07-01

... Practices for Gasoline Cargo Tanks Unloading at Gasoline Dispensing Facilities With Monthly Throughput of 100,000 Gallons of Gasoline or More 2 Table 2 to Subpart CCCCCC of Part 63 Protection of Environment... Pollutants for Source Category: Gasoline Dispensing Facilities Pt. 63, Subpt. CCCCCC, Table 2 Table 2 to...

40 CFR Table 2 to Subpart Cccccc... - Applicability Criteria and Management Practices for Gasoline Cargo Tanks Unloading at Gasoline...

Code of Federal Regulations, 2012 CFR

2012-07-01

... Practices for Gasoline Cargo Tanks Unloading at Gasoline Dispensing Facilities With Monthly Throughput of 100,000 Gallons of Gasoline or More 2 Table 2 to Subpart CCCCCC of Part 63 Protection of Environment... Pollutants for Source Category: Gasoline Dispensing Facilities Pt. 63, Subpt. CCCCCC, Table 2 Table 2 to...

Tables of E2 transition probabilities from the first 2 + states in even-even nuclei [B(E2) evaluation for 0 + 1 → 2 + 1 transitions in even-even nuclei

DOE PAGES

Pritychenko, B.; Birch, M.; Singh, B.; ...

2015-11-03

A complete B(E2)↑ evaluation and compilation for even-even nuclei has been presented. The present paper is a continuation of P.H. Stelson and L. Grodzins, and S. Raman et al. nuclear data evaluations and was motivated by a large number of new measurements. It extends the list of evaluated nuclides from 328 to 452, includes an extended list of nuclear reaction kinematics parameters and comprehensive shell model analysis. Evaluation policies for analysis of experimental data have been discussed and conclusions are given. Moreover, future plans for B(E2)↑ systematics and experimental technique analyses of even-even nuclei are outlined.

Lattice Thermal Conductivity from Atomistic Simulations: ZrB2 and HfB2

NASA Technical Reports Server (NTRS)

Lawson, John W.; Daw, Murray S.; Bauschlicher, Charles W.

2012-01-01

Ultra high temperature ceramics (UHTC) including ZrB2 and HfB2 have a number of properties that make them attractive for applications in extreme environments. One such property is their high thermal conductivity. Computational modeling of these materials will facilitate understanding of fundamental mechanisms, elucidate structure-property relationships, and ultimately accelerate the materials design cycle. Progress in computational modeling of UHTCs however has been limited in part due to the absence of suitable interatomic potentials. Recently, we developed Tersoff style parameterizations of such potentials for both ZrB2 and HfB2 appropriate for atomistic simulations. As an application, Green-Kubo molecular dynamics simulations were performed to evaluate the lattice thermal conductivity for single crystals of ZrB2 and HfB2. The atomic mass difference in these binary compounds leads to oscillations in the time correlation function of the heat current, in contrast to the more typical monotonic decay seen in monoatomic materials such as Silicon, for example. Results at room temperature and at elevated temperatures will be reported.

Translational studies support a role for serotonin 2B receptor (HTR2B) gene in aggression-related cannabis response.

PubMed

Montalvo-Ortiz, Janitza L; Zhou, Hang; D'Andrea, Ivana; Maroteaux, Luc; Lori, Adriana; Smith, Alicia; Ressler, Kerry J; Nuñez, Yaira Z; Farrer, Lindsay A; Zhao, Hongyu; Kranzler, Henry R; Gelernter, Joel

2018-06-06

Cannabis use is increasing in the United States, as are its adverse effects. We investigated the genetics of an adverse consequence of cannabis use: cannabis-related aggression (CRA) using a genome-wide association study (GWAS) design. Our GWAS sample included 3269 African Americans (AAs) and 2546 European Americans (EAs). An additional 89 AA subjects from the Grady Trauma Project (GTP) were also examined using a proxy-phenotype replication approach. We identified genome-wide significant risk loci contributing to CRA in AAs at the serotonin receptor 2B receptor gene (HTR2B), and the lead SNP, HTR2B*rs17440378, showed nominal association to aggression in the GTP cohort of cannabis-exposed subjects. A priori evidence linked HTR2B to impulsivity/aggression but not to cannabis response. Human functional data regarding the HTR2B variant further supported our finding. Treating an Htr2b -/- knockout mouse with THC resulted in increased aggressive behavior, whereas wild-type mice following THC administration showed decreased aggression in the resident-intruder paradigm, demonstrating that HTR2B variation moderates the effects of cannabis on aggression. These concordant findings in mice and humans implicate HTR2B as a major locus associated with cannabis-induced aggression.

26 CFR 1.430(h)(3)-2 - Plan-specific substitute mortality tables used to determine present value.

Code of Federal Regulations, 2010 CFR

2010-04-01

... to determine present value. 1.430(h)(3)-2 Section 1.430(h)(3)-2 Internal Revenue INTERNAL REVENUE... § 1.430(h)(3)-2 Plan-specific substitute mortality tables used to determine present value. (a) In general. This section sets forth rules for the use of substitute mortality tables under section 430(h)(3...

Collaborative study for the establishment of the 2(nd) International Standard for Bleomycin Complex A2/B2.

PubMed

Jorajuria, S; Raphalen, C; Dujardin, V; Daas, A

2015-01-01

Organization (WHO) International Standard (IS) for bleomycin complex A2/B2. Eight laboratories from different countries participated. Potencies of the candidate material were estimated by microbiological assays with sensitive micro-organisms. To ensure continuity between consecutive batches, the 1(st) IS for bleomycin complex A2/B2 was used as a reference. Based on the results of the study, the 2(nd) IS for bleomycin complex A2/B2 was adopted at the meeting of the WHO Expert Committee for Biological Standardization (ECBS) in 2014 with an assigned potency of 12 500 International Units (IU) per vial. The 2(nd) IS for bleomycin complex A2/B2 is available from the European Directorate for the Quality of Medicines & HealthCare (EDQM).

Atmospheric circulation of eccentric hot Jupiter HAT-P-2B

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lewis, Nikole K.; Showman, Adam P.; Fortney, Jonathan J.

The hot Jupiter HAT-P-2b has become a prime target for Spitzer Space Telescope observations aimed at understanding the atmospheric response of exoplanets on highly eccentric orbits. Here we present a suite of three-dimensional atmospheric circulation models for HAT-P-2b that investigate the effects of assumed atmospheric composition and rotation rate on global scale winds and thermal patterns. We compare and contrast atmospheric models for HAT-P-2b, which assume one and five times solar metallicity, both with and without TiO/VO as atmospheric constituents. Additionally we compare models that assume a rotation period of half, one, and two times the nominal pseudo-synchronous rotation period.more » We find that changes in assumed atmospheric metallicity and rotation rate do not significantly affect model predictions of the planetary flux as a function of orbital phase. However, models in which TiO/VO are present in the atmosphere develop a transient temperature inversion between the transit and secondary eclipse events that results in significant variations in the timing and magnitude of the peak of the planetary flux compared with models in which TiO/VO are omitted from the opacity tables. We find that no one single atmospheric model can reproduce the recently observed full orbit phase curves at 3.6, 4.5 and 8.0 μm, which is likely due to a chemical process not captured by our current atmospheric models for HAT-P-2b. Further modeling and observational efforts focused on understanding the chemistry of HAT-P-2b's atmosphere are needed and could provide key insights into the interplay between radiative, dynamical, and chemical processes in a wide range of exoplanet atmospheres.« less

HSD3B2, HSD17B1, HSD17B2, ESR1, ESR2 and AR expression in infertile women with endometriosis.

PubMed

Osiński, Maciej; Wirstlein, Przemysław; Wender-Ożegowska, Ewa; Mikołajczyk, Mateusz; Jagodziński, Paweł Piotr; Szczepańska, Małgorzata

2018-01-01

The development of endometriosis is associated with changes in the expression of genes encoding the 3β-hydroxysteroid dehydrogenase type II (HSD3B2) and 17β-hydroxysteroid dehydrogenase type II (HSD17B2), estrogen receptors 1 (ESR1) and 2 (ESR2) and the androgen receptor (AR). However, little is known about the expression of HSD3B2, HSD17B1, HSD17B2, ESR1 ESR2 and AR during the endometrial phases in eutopic endometrium from infertile women with endometriosis. Using RT-qPCR analysis, we assessed the expression of the studied genes in the follicular and luteal phases in eutopic endometrium from fertile women (n = 17) and infertile women (n = 35) with endometriosis. In the mid-follicular eutopic endometrium, we observed a significant increase in HSD3B2 transcript levels in all infertile women with endometriosis (p = 0.003), in infertile women with stage I/II endometriosis (p = 0.008) and in infertile women with stage III/IV endometriosis (p = 0.009) compared to all fertile women. There was a significant increase in ESR1 tran-scripts in all infertile women with endometriosis (p = 0.008) and in infertile women with stage I/II endometriosis (p = 0.019) and in infertile women with stage III/IV endometriosis (p = 0.023) compared to all fertile women. In the mid-luteal eutopic endometrium, we did not observe significant differences in HSD3B2, HSD17B1, HSD17B2, ESR1, ESR2 and AR transcripts between infertile women with endometriosis and fertile women. Observed significant increase in HSD3B2 and ESR1 transcripts in follicular eutopic endometrium from infer-tile women with endometriosis may be related to abnormal biological effect of E2 in endometrium, further affecting the development of human embryos.

Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients

PubMed Central

Romero-Lorca, Alicia; Novillo, Apolonia; Gaibar, María; Bandrés, Fernando; Fernández-Santander, Ana

2015-01-01

Tamoxifen is used to prevent and treat estrogen-dependent breast cancer. It is described as a prodrug since most of its antiestrogen effects are exerted through its hydroxylated metabolites 4-OH-tamoxifen and endoxifen. In prior work, we correlated optimal plasma levels of these metabolites with certain genotypes of CYP2D6 and SULT1A2. This descriptive study examines correlations between concentrations of tamoxifen's glucuronide metabolites and genotypes UGT1A4 Pro24Thr, UGT1A4 Leu48Val, UGT2B7 His268Tyr, UGT2B15 Asp85YTyr UGT2B15 Lys523Thr and UGT2B17del in 132 patients with estrogen receptor-positive breast cancer under treatment with tamoxifen. Patients were genotyped by real-time and conventional PCR-RFLP. The glucuronides 4-OH-tamoxifen-N-glucuronide, 4-OH-tamoxifen-O-glucuronide and endoxifen-O-glucuronide were isolated from blood plasma and quantified using a high-pressure liquid chromatography-tandem mass spectrometry system. Individuals who were homozygous for UGT1A448VAL showed significantly lower mean concentrations of both glucuronide metabolites compared to subjects genotyped as wt/wt plus wt/48Val (p=0.037 and p=0.031, respectively). Women homozygous for UGT2B7268Tyr also showed mean substrate/product ratios of 4-OH-tamoxifen/4-OH-tamoxifen-O-glucuronide and 4-OH-tamoxifen/4-OH-tamoxifen-N-glucuronide indicative of reduced glucuronidase activity compared to wt homozygotes or to heterozygotes for the polymorphism (p=0.005 and p=0.003, respectively). In contrast, UGT2B15 Lys523Thr and UGT2B17del were associated with possibly increased enzyme activity. Patients with at least one variant allele UGT2B15523Thr showed significantly higher 4-OH-tamoxifen-O-glucuronide and endoxifen-glucuronide levels (p=0.023 and p=0.025, respectively) indicating a variant gene-dose effect. Higher 4-OH-tamoxifen-N-glucuronide levels observed in UGT2B17del genotypes (p=0.042) could be attributed to a mechanism that compensates for the greater expression of other genes in UGT2B

Phase and Physicochemical Properties Diagrams of Quaternary System Li2B4O7 + Na2B4O7 + Mg2B6O11 + H2O

NASA Astrophysics Data System (ADS)

Wang, Shi-qiang; Du, Xue-min; Jing, Yan; Guo, Ya-fei; Deng, Tian-long

2017-12-01

The phase and physicochemical properties diagrams of the quaternary system (Li2B4O7 + Na2B4O7 + Mg2B6O11) at 288.15 K and 0.1 MPa were constructed using the solubilities, densities, and refractive indices measured. In the phase diagrams of the system there are one invariant point, three univariant isothermic dissolution curves, and three crystallization regions corresponding to Li2B4O7 · 3H2O, Na2B4O7 · 10H2O, and Mg2B6O11 · 15H2O, respectively. The solution density, refractive index of the quaternary system changes regularly with the increasing of Li2B4O7 concentration. The calculated values of density and refractive index using empirical equations of the quaternary system are in good agreement with the experimental values.

40 CFR Table E-2 to Subpart E of... - Spectral Energy Distribution and Permitted Tolerance for Conducting Radiative Tests

Code of Federal Regulations, 2010 CFR

2010-07-01

... Permitted Tolerance for Conducting Radiative Tests E Table E-2 to Subpart E of Part 53 Protection of... Reference Methods and Class I and Class II Equivalent Methods for PM2.5 or PM10â2.5 Pt. 53, Subpt. E, Table E-2 Table E-2 to Subpart E of Part 53—Spectral Energy Distribution and Permitted Tolerance for...

Inelastic scattering matrix elements for the nonadiabatic collision B(2P1/2)+H2(1Sigmag+,j)<-->B(2P3/2)+H2(1Sigmag+,j').

PubMed

Weeks, David E; Niday, Thomas A; Yang, Sang H

2006-10-28

Inelastic scattering matrix elements for the nonadiabatic collision B(2P1/2)+H2(1Sigmag+,j)<-->B(2P3/2)+H2(1Sigmag+,j') are calculated using the time dependent channel packet method (CPM). The calculation employs 1 2A', 2 2A', and 1 2A" adiabatic electronic potential energy surfaces determined by numerical computation at the multireference configuration-interaction level [M. H. Alexander, J. Chem. Phys. 99, 6041 (1993)]. The 1 2A' and 2 2A', adiabatic electronic potential energy surfaces are transformed to yield diabatic electronic potential energy surfaces that, when combined with the total B+H2 rotational kinetic energy, yield a set of effective potential energy surfaces [M. H. Alexander et al., J. Chem. Phys. 103, 7956 (1995)]. Within the framework of the CPM, the number of effective potential energy surfaces used for the scattering matrix calculation is then determined by the size of the angular momentum basis used as a representation. Twenty basis vectors are employed for these calculations, and the corresponding effective potential energy surfaces are identified in the asymptotic limit by the H2 rotor quantum numbers j=0, 2, 4, 6 and B electronic states 2Pja, ja=1/2, 3/2. Scattering matrix elements are obtained from the Fourier transform of the correlation function between channel packets evolving in time on these effective potential energy surfaces. For these calculations the H2 bond length is constrained to a constant value of req=1.402 a.u. and state to state scattering matrix elements corresponding to a total angular momentum of J=1/2 are discussed for j=0<-->j'=0,2,4 and 2P1/2<-->2P1/2, 2P3/2 over a range of total energy between 0.0 and 0.01 a.u.

The Vaiont Slide. A Geotechnical Analysis Based on New Geologic Observations of the Failure Surface. Volume 2. Appendices A through G

DTIC Science & Technology

1985-06-01

Al B , STATIC SLOPE ANALYSIS METHOD USED FOR THE WAONT SLIDE -ANALYSES~ty D. L. Anderson ................................... B1 C SECTIONS,,USED...years 1960, 1961, 1962 and 1963 are given in this appendix in Tables Al , A2, A3 and A4, respectively. These were supplied through the courtesy of E.N.E.L...Tables Table Al . Daily precipitation record, Erto - 1960 Table A2. Daily precipitation record, Erto - 1961 Table A3. Daily precipitation record, Erto

New analytical techniques for mycotoxins in complex organic matrices. [Aflatoxins B1, B2, G1, and G2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bicking, M.K.L.

1982-07-01

Air samples are collected for analysis from the Ames Solid Waste Recovery System. The high level of airborne fungi within the processing area is of concern due to the possible presence of toxic mycotoxins, and carcinogenic fungal metabolites. An analytical method has been developed to determine the concentration of aflatoxins B1, B2, G1, and G2 in the air of the plant which produces Refuse Derived Fuel (RDF). After extraction with methanol, some components in the matrix are precipitated by dissolving the sample in 30% acetonitrile/chloroform. An aliquot of this solution is injected onto a Styragel column where the sample componentsmore » undergo simultaneous size exclusion and reverse phase partitioning. Additional studies have provided a more thorough understanding of solvent related non-exclusion effects on size exclusion gels. The Styragel column appears to have a useable lifetime of more than six months. After elution from Styragel, the sample is diverted to a second column containing Florisil which has been modified with oxalic acid and deactivated with water. Aflatoxins are eluted with 5% water/acetone. After removal of this solvent, the sample is dissolved in 150 ..mu..L of a spotting solvent and the entire sample applied to a thin layer chromatography (TLC) plate using a unique sample applicator developed here. The aflatoxins on the TLC plate are analyzed by laser fluorescence. A detection limit of 10 pg is possible for aflatoxin standards using a nitrogen laser as the excitation source. Sample concentrations are determined by comparing with an internal standard, a specially synthesized aflatoxin derivative. In two separate RDF samples, aflatoxin B1 was found at levels of 6.5 and 17.0 ppB. The analytical method has also proven useful in the analysis of contaminated corn and peanut meal samples. 42 figures, 8 tables.« less

40 CFR Table 2 to Subpart Jjj of... - Class I Emission Limits for Existing Small Municipal Waste Combustion Limits

Code of Federal Regulations, 2010 CFR

2010-07-01

... Small Municipal Waste Combustion Limits 2 Table 2 to Subpart JJJ of Part 62 Protection of Environment... Combustion Units Constructed on or Before August 30, 1999 Pt. 62, Subpt. JJJ, Table 2 Table 2 to Subpart JJJ of Part 62—Class I Emission Limits for Existing Small Municipal Waste Combustion Limits ER31JA03.006...

40 CFR Table 2 to Subpart Jjj of... - Class I Emission Limits for Existing Small Municipal Waste Combustion Limits

Code of Federal Regulations, 2013 CFR

2013-07-01

... Small Municipal Waste Combustion Limits 2 Table 2 to Subpart JJJ of Part 62 Protection of Environment... Combustion Units Constructed on or Before August 30, 1999 Pt. 62, Subpt. JJJ, Table 2 Table 2 to Subpart JJJ of Part 62—Class I Emission Limits for Existing Small Municipal Waste Combustion Limits ER31JA03.006...

40 CFR Table 2 to Subpart Jjj of... - Class I Emission Limits for Existing Small Municipal Waste Combustion Limits

Code of Federal Regulations, 2011 CFR

2011-07-01

... Small Municipal Waste Combustion Limits 2 Table 2 to Subpart JJJ of Part 62 Protection of Environment... Combustion Units Constructed on or Before August 30, 1999 Pt. 62, Subpt. JJJ, Table 2 Table 2 to Subpart JJJ of Part 62—Class I Emission Limits for Existing Small Municipal Waste Combustion Limits ER31JA03.006...

40 CFR Table 2 to Subpart Jjj of... - Class I Emission Limits for Existing Small Municipal Waste Combustion Limits

Code of Federal Regulations, 2012 CFR

2012-07-01

... Small Municipal Waste Combustion Limits 2 Table 2 to Subpart JJJ of Part 62 Protection of Environment... Combustion Units Constructed on or Before August 30, 1999 Pt. 62, Subpt. JJJ, Table 2 Table 2 to Subpart JJJ of Part 62—Class I Emission Limits for Existing Small Municipal Waste Combustion Limits ER31JA03.006...

40 CFR Table 2 to Subpart Jjj of... - Class I Emission Limits for Existing Small Municipal Waste Combustion Limits

Code of Federal Regulations, 2014 CFR

2014-07-01

... Small Municipal Waste Combustion Limits 2 Table 2 to Subpart JJJ of Part 62 Protection of Environment... Combustion Units Constructed on or Before August 30, 1999 Pt. 62, Subpt. JJJ, Table 2 Table 2 to Subpart JJJ of Part 62—Class I Emission Limits for Existing Small Municipal Waste Combustion Limits ER31JA03.006...

B2B Models for DoD Acquisition

DTIC Science & Technology

2008-01-15

unlimited. Prepared for: Naval Postgraduate School, Monterey, California 93943 B2B Models for DoD Acquisition 15 January 2008 by Magdi N...TYPE AND DATES COVERED 1 Oct 2006 through 30 Sept 2007 4. TITLE AND SUBTITLE B2B Models for DoD Acquisition 5. FUNDING 6. AUTHOR (S...public release; distribution is unlimited 12b. DISTRIBUTION CODE 13. ABSTRACT (Maximum 200 words.) A central vision of B2B e-commerce is that

Interferon Alfa-2b Injection

MedlinePlus

Interferon alfa-2b injection is used to treat a number of conditions.Interferon alfa-2b injection is used alone or in combination ... lymphoma (NHL; a slow-growing blood cancer). Interferon alfa-2b is in a class of medications called ...

The nido-osmaboranes [2,2,2-(CO)(PPh(3))(2)-nido-2-OsB(5)H(9)] and [6,6,6-(CO)(PPh(3))(2)-nido-6-OsB(9)H(13)].

PubMed

Bould, J; Kennedy, J D; Thomas, R L; Rath, N P; Barton, L

2001-11-01

The structural characterization of the osmahexaborane 2-carbonyl-2,2-bis(triphenylphosphine)-nido-2-osmahexaborane(9), [Os(B(5)H(9))(C(18)H(15)P)(2)(CO)], (I), a metallaborane analogue of B(6)H(10), confirms the structure proposed from NMR spectroscopy. The structure of the osmadecaborane 6-carbonyl-6,6-bis(triphenylphosphine)-nido-6-osmadecaborane(13), [Os(B(9)H(13))(C(18)H(15)P)(2)(CO)], (IV), is similarly confirmed. The short basal B-B distance of 1.652 (8) A in (I), not bridged by an H atom, mirrors that in the parent hexaborane(10) [1.626 (4) A].

Axial point groups: rank 1, 2, 3 and 4 property tensor tables.

PubMed

Litvin, Daniel B

2015-05-01

The form of a physical property tensor of a quasi-one-dimensional material such as a nanotube or a polymer is determined from the material's axial point group. Tables of the form of rank 1, 2, 3 and 4 property tensors are presented for a wide variety of magnetic and non-magnetic tensor types invariant under each point group in all 31 infinite series of axial point groups. An application of these tables is given in the prediction of the net polarization and magnetic-field-induced polarization in a one-dimensional longitudinal conical magnetic structure in multiferroic hexaferrites.

Metallaborane reaction chemistry. A predicted and found tailored facile and reversible capture of SO2 by a B-frame-supported bimetallic: structures of [(PMe2Ph)2PtPd(phen)B10H10] and [(PMe2Ph)2Pt(SO2)Pd(phen)B10H10].

PubMed

Bould, Jonathan; Kennedy, John D

2008-06-07

The formally closo twelve-vertex {ortho-M2B10} dimetallaborane system has been predictively tailored for reversible uptake of SO2 across the metal-metal bond, as exemplified by the formation of [(PMe2Ph)2Pt(SO2)Pd(phen)B10H10] from [(PMe2Ph)2PtPd(phen)B10H10].

15 CFR Appendix B to Part 946 - Airport Tables

Code of Federal Regulations, 2014 CFR

2014-01-01

... OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE REGULATIONS OF THE NATIONAL WEATHER SERVICE MODERNIZATION OF THE NATIONAL WEATHER SERVICE Pt. 946, App. B Appendix B to Part 946—Airport Tables “A” Level...

15 CFR Appendix B to Part 946 - Airport Tables

Code of Federal Regulations, 2013 CFR

2013-01-01

... OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE REGULATIONS OF THE NATIONAL WEATHER SERVICE MODERNIZATION OF THE NATIONAL WEATHER SERVICE Pt. 946, App. B Appendix B to Part 946—Airport Tables “A” Level...

15 CFR Appendix B to Part 946 - Airport Tables

Code of Federal Regulations, 2010 CFR

2010-01-01

... OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE REGULATIONS OF THE NATIONAL WEATHER SERVICE MODERNIZATION OF THE NATIONAL WEATHER SERVICE Pt. 946, App. B Appendix B to Part 946—Airport Tables “A” Level...

15 CFR Appendix B to Part 946 - Airport Tables

Code of Federal Regulations, 2012 CFR

2012-01-01

... OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE REGULATIONS OF THE NATIONAL WEATHER SERVICE MODERNIZATION OF THE NATIONAL WEATHER SERVICE Pt. 946, App. B Appendix B to Part 946—Airport Tables “A” Level...

15 CFR Appendix B to Part 946 - Airport Tables

Code of Federal Regulations, 2011 CFR

2011-01-01

... OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE REGULATIONS OF THE NATIONAL WEATHER SERVICE MODERNIZATION OF THE NATIONAL WEATHER SERVICE Pt. 946, App. B Appendix B to Part 946—Airport Tables “A” Level...

40 CFR Table 2 to Subpart Pppp of... - Applicability of General Provisions to Subpart PPPP of Part 63

Code of Federal Regulations, 2010 CFR

2010-07-01

... of Plastic Parts and Products Pt. 63, Subpt. PPPP, Table 2 Table 2 to Subpart PPPP of Part 63...) Data Reduction No Sections 63.4567 and 63.4568 specify monitoring data reduction. § 63.9(a)-(d...

40 CFR Table 2 to Subpart Jjj of... - Group 1 Storage Vessels at Existing Affected Sources

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 12 2013-07-01 2013-07-01 false Group 1 Storage Vessels at Existing... SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutant Emissions: Group IV Polymers and Resins Pt. 63, Subpt. JJJ, Table 2 Table 2 to Subpart JJJ of Part 63—Group 1 Storage Vessels...

40 CFR Table 2 to Subpart Jjj of... - Group 1 Storage Vessels at Existing Affected Sources

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 12 2014-07-01 2014-07-01 false Group 1 Storage Vessels at Existing... SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutant Emissions: Group IV Polymers and Resins Pt. 63, Subpt. JJJ, Table 2 Table 2 to Subpart JJJ of Part 63—Group 1 Storage Vessels...

40 CFR Table 2 to Subpart Jjj of... - Group 1 Storage Vessels at Existing Affected Sources

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 11 2010-07-01 2010-07-01 true Group 1 Storage Vessels at Existing... SOURCE CATEGORIES National Emission Standards for Hazardous Air Pollutant Emissions: Group IV Polymers and Resins Pt. 63, Subpt. JJJ, Table 2 Table 2 to Subpart JJJ of Part 63—Group 1 Storage Vessels at...

40 CFR Table 2 to Subpart Jjj of... - Group 1 Storage Vessels at Existing Affected Sources

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 12 2012-07-01 2011-07-01 true Group 1 Storage Vessels at Existing... SOURCE CATEGORIES National Emission Standards for Hazardous Air Pollutant Emissions: Group IV Polymers and Resins Pt. 63, Subpt. JJJ, Table 2 Table 2 to Subpart JJJ of Part 63—Group 1 Storage Vessels at...

40 CFR Table 2 to Subpart Jjj of... - Group 1 Storage Vessels at Existing Affected Sources

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 11 2011-07-01 2011-07-01 false Group 1 Storage Vessels at Existing... SOURCE CATEGORIES National Emission Standards for Hazardous Air Pollutant Emissions: Group IV Polymers and Resins Pt. 63, Subpt. JJJ, Table 2 Table 2 to Subpart JJJ of Part 63—Group 1 Storage Vessels at...

The H2A.Z/H2B dimer is unstable compared to the dimer containing the major H2A isoform.

PubMed

Placek, Brandon J; Harrison, L Nicole; Villers, Brooke M; Gloss, Lisa M

2005-02-01

The nucleosome, the basic fundamental repeating unit of chromatin, contains two H2A/H2B dimers and an H3/H4 tetramer. Modulation of the structure and dynamics of the nucleosome is an important regulation mechanism of DNA-based chemistries in the eukaryotic cell, such as transcription and replication. One means of altering the properties of the nucleosome is by incorporation of histone variants. To provide insights into how histone variants may impact the thermodynamics of the nucleosome, the stability of the heterodimer between the H2A.Z variant and H2B was determined by urea-induced denaturation, monitored by far-UV circular dichroism, intrinsic Tyr fluorescence intensity, and anisotropy. In the absence of stabilizing agents, the H2A.Z/H2B dimer is only partially folded. The stabilizing cosolute, trimethylamine-N-oxide (TMAO) was used to promote folding of the unstable heterodimer. The equilibrium stability of the H2A.Z/H2B dimer is compared to that of the H2A/H2B dimer. The equilibrium folding of both histone dimers is highly reversible and best described by a two-state model, with no detectable equilibrium intermediates populated. The free energies of unfolding, in the absence of denaturant, of H2A.Z/H2B and H2A/H2B are 7.3 kcal mol(-1) and 15.5 kcal mol(-1), respectively, in 1 M TMAO. The H2A.Z/H2B dimer is the least stable histone fold characterized to date, while H2A/H2B appears to be the most stable. It is speculated that this difference in stability may contribute to the different biophysical properties of nucleosomes containing the major H2A and the H2A.Z variant.

A Low-Complexity and High-Performance 2D Look-Up Table for LDPC Hardware Implementation

NASA Astrophysics Data System (ADS)

Chen, Jung-Chieh; Yang, Po-Hui; Lain, Jenn-Kaie; Chung, Tzu-Wen

In this paper, we propose a low-complexity, high-efficiency two-dimensional look-up table (2D LUT) for carrying out the sum-product algorithm in the decoding of low-density parity-check (LDPC) codes. Instead of employing adders for the core operation when updating check node messages, in the proposed scheme, the main term and correction factor of the core operation are successfully merged into a compact 2D LUT. Simulation results indicate that the proposed 2D LUT not only attains close-to-optimal bit error rate performance but also enjoys a low complexity advantage that is suitable for hardware implementation.

50 CFR Table 2 to Part 226 - Major Stellar Sea Lion Haulout Sites in Alaska

Code of Federal Regulations, 2012 CFR

2012-10-01

... 50 Wildlife and Fisheries 10 2012-10-01 2012-10-01 false Major Stellar Sea Lion Haulout Sites in.... 226, Table 2 Table 2 to Part 226—Major Stellar Sea Lion Haulout Sites in Alaska Major Steller sea lion... 19.5W Tigalda I. 1 54 08.5N 164 58.5W Umnak I./Cape Aslik 1 53 25.0N 168 24.5W Bering Sea: Cape...

50 CFR Table 2 to Part 226 - Major Stellar Sea Lion Haulout Sites in Alaska

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Major Stellar Sea Lion Haulout Sites in.... 226, Table 2 Table 2 to Part 226—Major Stellar Sea Lion Haulout Sites in Alaska Major Steller sea lion... 19.5W Tigalda I. 1 54 08.5N 164 58.5W Umnak I./Cape Aslik 1 53 25.0N 168 24.5W Bering Sea: Cape...

B2B Models for DoD Acquisition

DTIC Science & Technology

2007-07-30

Internet, extranets, intranets, or private networks • In 2003 it represented about 11% of total B2B trade estimated at $13.5 trillion • Predicted to... B2B Models for DoD Acquisition 30 July 2007 by Magdi N. Kamel, Associate Professor Graduate School of Operational & Information Sciences...number. 1. REPORT DATE 30 JUL 2007 2. REPORT TYPE 3. DATES COVERED 00-00-2007 to 00-00-2007 4. TITLE AND SUBTITLE B2B Models for DoD

40 CFR Table Hh-2 to Subpart Hh of... - U.S. Per Capita Waste Disposal Rates

Code of Federal Regulations, 2011 CFR

2011-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Municipal Solid Waste Landfills Pt. 98, Subpt. HH, Table HH-2 Table HH-2 to Subpart HH of Part 98—U.S. Per Capita Waste Disposal Rates... 40 Protection of Environment 21 2011-07-01 2011-07-01 false U.S. Per Capita Waste Disposal Rates...

MASCARA-2 b. A hot Jupiter transiting the mV = 7.6 A-star HD 185603

NASA Astrophysics Data System (ADS)

Talens, G. J. J.; Justesen, A. B.; Albrecht, S.; McCormac, J.; Van Eylen, V.; Otten, G. P. P. L.; Murgas, F.; Palle, E.; Pollacco, D.; Stuik, R.; Spronck, J. F. P.; Lesage, A.-L.; Grundahl, F.; Fredslund Andersen, M.; Antoci, V.; Snellen, I. A. G.

2018-04-01

In this paper we present MASCARA-2 b, a hot Jupiter transiting the mV = 7.6 A2 star HD 185603. Since early 2015, MASCARA has taken more than 1.6 million flux measurements of the star, corresponding to a total of almost 3000 h of observations, revealing a periodic dimming in the flux with a depth of 1.3%. Photometric follow-up observations were performed with the NITES and IAC80 telescopes and spectroscopic measurements were obtained with the Hertzsprung SONG telescope. We find MASCARA-2 b orbits HD 185603 with a period of 3.4741119-0.000006+0.000005 at a distance of 0.057 ± 0.006 au, has a radius of 1.83 ± 0.07 RJ and place a 99% upper limit on the mass of <17 MJ. HD 185603 is a rapidly rotating early-type star with an effective temperature of 8980-130+90 K and a mass and radius of 1.89-0.05+0.06 M⊙, 1.60 ± 0.06 R⊙, respectively. Contrary to most other hot Jupiters transiting early-type stars, the projected planet orbital axis and stellar spin axis are found to be aligned with λ = 0.6 ± 4°. The brightness of the host star and the high equilibrium temperature, 2260 ± 50 K, of MASCARA-2 b make it a suitable target for atmospheric studies from the ground and space. Of particular interest is the detection of TiO, which has recently been detected in the similarly hot planets WASP-33 b and WASP-19 b. Tables of photometry are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/612/A57

Nucleoplasmin Binds Histone H2A-H2B Dimers through Its Distal Face*

PubMed Central

Ramos, Isbaal; Martín-Benito, Jaime; Finn, Ron; Bretaña, Laura; Aloria, Kerman; Arizmendi, Jesús M.; Ausió, Juan; Muga, Arturo; Valpuesta, José M.; Prado, Adelina

2010-01-01

Nucleoplasmin (NP) is a pentameric chaperone that regulates the condensation state of chromatin extracting specific basic proteins from sperm chromatin and depositing H2A-H2B histone dimers. It has been proposed that histones could bind to either the lateral or distal face of the pentameric structure. Here, we combine different biochemical and biophysical techniques to show that natural, hyperphosphorylated NP can bind five H2A-H2B dimers and that the amount of bound ligand depends on the overall charge (phosphorylation level) of the chaperone. Three-dimensional reconstruction of NP/H2A-H2B complex carried out by electron microscopy reveals that histones interact with the chaperone distal face. Limited proteolysis and mass spectrometry indicate that the interaction results in protection of the histone fold and most of the H2A and H2B C-terminal tails. This structural information can help to understand the function of NP as a histone chaperone. PMID:20696766

Possible involvement of nuclear factor erythroid 2-related factor 2 in the gene expression of Cyp2b10 and Cyp2a5.

PubMed

Ashino, Takashi; Ohkubo-Morita, Haruyo; Yamamoto, Masayuki; Yoshida, Takemi; Numazawa, Satoshi

2014-01-01

Cytochrome P450 gene expression is altered by various chemical compounds. In this study, we used nuclear factor erythroid 2-related factor 2 (Nrf2)-deficient (Nrf2(-⧸-)) mice to investigate the involvement of Nrf2 in Cyp2b10 and Cyp2a5 gene expression. Phorone, an Nrf2 activator, strongly increased Cyp2b10 and Cyp2a5 mRNA as well as Nrf2 target genes, including NAD(P)H-quinone oxidoreductase-1 and heme oxygenase-1, in wild-type mouse livers 8 h after treatment. The phorone-induced mRNA levels in Nrf2(-⧸-) mouse livers were lower than that in wild-type mouse livers. Nrf2(-⧸-) mice showed attenuated Cyp2b10 and Cyp2a5 induction by phenobarbital, a classical Cyp2b inducer. These findings suggest that the Nrf2 pathway is involved in Cyp2b10 and Cyp2a5 gene expression.

EUDAT B2FIND : A Cross-Discipline Metadata Service and Discovery Portal

NASA Astrophysics Data System (ADS)

Widmann, Heinrich; Thiemann, Hannes

2016-04-01

The European Data Infrastructure (EUDAT) project aims at a pan-European environment that supports a variety of multiple research communities and individuals to manage the rising tide of scientific data by advanced data management technologies. This led to the establishment of the community-driven Collaborative Data Infrastructure that implements common data services and storage resources to tackle the basic requirements and the specific challenges of international and interdisciplinary research data management. The metadata service B2FIND plays a central role in this context by providing a simple and user-friendly discovery portal to find research data collections stored in EUDAT data centers or in other repositories. For this we store the diverse metadata collected from heterogeneous sources in a comprehensive joint metadata catalogue and make them searchable in an open data portal. The implemented metadata ingestion workflow consists of three steps. First the metadata records - provided either by various research communities or via other EUDAT services - are harvested. Afterwards the raw metadata records are converted and mapped to unified key-value dictionaries as specified by the B2FIND schema. The semantic mapping of the non-uniform, community specific metadata to homogenous structured datasets is hereby the most subtle and challenging task. To assure and improve the quality of the metadata this mapping process is accompanied by • iterative and intense exchange with the community representatives, • usage of controlled vocabularies and community specific ontologies and • formal and semantic validation. Finally the mapped and checked records are uploaded as datasets to the catalogue, which is based on the open source data portal software CKAN. CKAN provides a rich RESTful JSON API and uses SOLR for dataset indexing that enables users to query and search in the catalogue. The homogenization of the community specific data models and vocabularies enables not

50 CFR Table 2 to Part 226 - Major Steller Sea Lion Haulout Sites in Alaska

Code of Federal Regulations, 2014 CFR

2014-10-01

... 50 Wildlife and Fisheries 10 2014-10-01 2014-10-01 false Major Steller Sea Lion Haulout Sites in.... 226, Table 2 Table 2 to Part 226—Major Steller Sea Lion Haulout Sites in Alaska Major Steller sea lion...: Northeast Point 1 57 15.0N 170 06.5W Sea Lion Rock 1 57 06.0N 170 17.5W St. George I: S Rookery 1 56 33.5N...

50 CFR Table 2 to Part 226 - Major Stellar Sea Lion Haulout Sites in Alaska

Code of Federal Regulations, 2013 CFR

2013-10-01

... 50 Wildlife and Fisheries 10 2013-10-01 2013-10-01 false Major Stellar Sea Lion Haulout Sites in.... 226, Table 2 Table 2 to Part 226—Major Stellar Sea Lion Haulout Sites in Alaska Major Steller sea lion...: Northeast Point 1 57 15.0N 170 06.5W Sea Lion Rock 1 57 06.0N 170 17.5W St. George I: S Rookery 1 56 33.5N...

50 CFR Table 2a to Part 660... - 2012, and beyond, Specifications of OFL, ABC, ACL, ACT and Fishery Harvest guidelines (weights in...

Code of Federal Regulations, 2012 CFR

2012-10-01

... 50 Wildlife and Fisheries 13 2012-10-01 2012-10-01 false 2012, and beyond, Specifications of OFL, ABC, ACL, ACT and Fishery Harvest guidelines (weights in metric tons) 2a Table 2a to Part 660, Subpart... Table 2a to Part 660, Subpart C—2012, and beyond, Specifications of OFL, ABC, ACL, ACT and Fishery...

50 CFR Table 2a to Part 660... - 2014, and Beyond, Specifications of OFL, ABC, ACL, ACT and Fishery Harvest guidelines (weights in...

Code of Federal Regulations, 2014 CFR

2014-10-01

... 50 Wildlife and Fisheries 13 2014-10-01 2014-10-01 false 2014, and Beyond, Specifications of OFL, ABC, ACL, ACT and Fishery Harvest guidelines (weights in metric tons) 2a Table 2a to Part 660, Subpart... Table 2a to Part 660, Subpart C—2014, and Beyond, Specifications of OFL, ABC, ACL, ACT and Fishery...

D1((2)B2g) to D0((2)Au) Fluorescence from the Matrix-Isolated Perylene Cation Following Laser Excitation into the D5(2)B3g) and D2 ((2)B3g) Electronic States

NASA Technical Reports Server (NTRS)

Chillier, Xavier D. F.; Stone, Bradley M.; Joblin, Christine; Salama, Farid; Allamandola, Louis J.; DeVincenzi, Donald L. (Technical Monitor)

2001-01-01

Fluorescence spectra of the perylene cation, pumped by direct laser excitation via the D(sub 2)((2)B(sub 3g)) (left arrow) D(sub 0)((2)A(sub u)) and D(sub 5)(2)B(sub 3g)) (left arrow) D(sub 0)((2)A(sub u)) transitions, are presented. Direct excitation into the D5 or D2 states is followed by rapid non-radiative relaxation to D1 that, in turn,relaxes radiatively. Excitation spectroscopy across the D(sub 2)((2)B(sub 3g)) (left arrow) D(sub 0)((2)A(sub u)) transition near 730 nm shows that site splitting plays little or no role in determining the spectral substructure in the ion spectra. Tentative assignments for ground state vibrational frequencies are made by comparison of spectral intervals with calculated normal mode frequencies.

The physical and chemical structure of Sagittarius B2. II. Continuum millimeter emission of Sgr B2(M) and Sgr B2(N) with ALMA

NASA Astrophysics Data System (ADS)

Sánchez-Monge, Á.; Schilke, P.; Schmiedeke, A.; Ginsburg, A.; Cesaroni, R.; Lis, D. C.; Qin, S.-L.; Müller, H. S. P.; Bergin, E.; Comito, C.; Möller, Th.

2017-07-01

Context. The two hot molecular cores Sgr B2(M) and Sgr B2(N), which are located at the center of the giant molecular cloud complex Sagittarius B2, have been the targets of numerous spectral line surveys, revealing a rich and complex chemistry. Aims: We seek to characterize the physical and chemical structure of the two high-mass star-forming sites Sgr B2(M) and Sgr B2(N) using high-angular resolution observations at millimeter wavelengths, reaching spatial scales of about 4000 au. Methods: We used the Atacama Large Millimeter/submillimeter Array (ALMA) to perform an unbiased spectral line survey of both regions in the ALMA band 6 with a frequency coverage from 211 GHz to 275 GHz. The achieved angular resolution is 0.̋4, which probes spatial scales of about 4000 au, I.e., able to resolve different cores and fragments. In order to determine the continuum emission in these line-rich sources, we used a new statistical method, STATCONT, which has been applied successfully to this and other ALMA datasets and to synthetic observations. Results: We detect 27 continuum sources in Sgr B2(M) and 20 sources in Sgr B2(N). We study the continuum emission variation across the ALMA band 6 (I.e., spectral index) and compare the ALMA 1.3 mm continuum emission with previous SMA 345 GHz and VLA 40 GHz observations to study the nature of the sources detected. The brightest sources are dominated by (partially optically thick) dust emission, while there is an important degree of contamination from ionized gas free-free emission in weaker sources. While the total mass in Sgr B2(M) is distributed in many fragments, most of the mass in Sgr B2(N) arises from a single object, with filamentary-like structures converging toward the center. There seems to be a lack of low-mass dense cores in both regions. We determine H2 volume densities for the cores of about 107-109 cm-3 (or 105-107 M⊙ pc-3), I.e., one to two orders of magnitude higher than the stellar densities of super star clusters. We

Synthesis of Substituted 2,3,5,6-tetraarylbenzo(1,2-b:5,4-b')difurans

NASA Technical Reports Server (NTRS)

Abdul-Aziz, Mahmoud; Auping, Judith V.; Meador, Michael A.

1995-01-01

A series of substituted 2,3,5,6-tetraarylbenzo(l,2-b:5,4-b')difurans 1 was synthesized. This synthesis is based upon the photocyclization of 2,5-dibenzoylresorcinol dibenzyl ethers to the corresponding tetrahydrobenzo(1,2-b:5,4-b')difurans. Treatment of the photoproducts with methanesulfonyl chloride in pyridine afforded 1 in overall yields ranging from 30-72%. A number of these compounds have high fluorescence quantum yields (of phi(sub f) = 0.76-0.90), and their fluorescence spectra exhibit large solvatochromic shifts. These compounds may be suitable for use as fluorescent probes.

30 CFR 250.1200 - Question index table.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Question index table. 250.1200 Section 250.1200..., Surface Commingling, and Security § 250.1200 Question index table. The table in this section lists...(a) 20. What are the requirements for a periodic well test used for allocation? § 250.1204(b) 21...

30 CFR 250.1200 - Question index table.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Question index table. 250.1200 Section 250.1200..., Surface Commingling, and Security § 250.1200 Question index table. The table in this section lists...(a) 20. What are the requirements for a periodic well test used for allocation? § 250.1204(b) 21...

30 CFR 250.1200 - Question index table.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Question index table. 250.1200 Section 250.1200..., Surface Commingling, and Security § 250.1200 Question index table. The table in this section lists...(a) 20. What are the requirements for a periodic well test used for allocation? § 250.1204(b) 21...

40 CFR Table A-3 to Subpart A of... - Source Category List for § 98.2(a)(1)

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Source Category List for § 98.2(a)(1) A Table A-3 to Subpart A of Part 98 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING General Provision Pt. 98, Subpt. A...

40 CFR Table A-3 to Subpart A of... - Source Category List for § 98.2(a)(1)

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Source Category List for § 98.2(a)(1) A Table A-3 to Subpart A of Part 98 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING General Provision Pt. 98, Subpt. A...

40 CFR Table A-3 to Subpart A of... - Source Category List for § 98.2(a)(1)

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Source Category List for § 98.2(a)(1) A Table A-3 to Subpart A of Part 98 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING General Provision Pt. 98, Subpt. A...

The CVD ZrB2 as a selective solar absorber

NASA Astrophysics Data System (ADS)

Randich, E.; Allred, D. D.

Coatings of ZrB2 and TiB2 for photothermal solar absorber applications were prepared using chemical vapor deposition (CVD) techniques. Oxidation tests suggest a maximum temperature limit for air exposure of 600 K for TiB2 and 800 K for Z4B2. Both materials exhibit innate spectral selectivity with emittance at 375 K ranging from 0.06 to 0.09 and solar absorptance for ZrB2 ranging from 0.67 to 0.77 and solar absorptance for TiB2 ranging from 0.46 to 0.58. ZrB2 has better solar selectivity and more desirable oxidation behavior than TiB2. A 0.071 micrometer antireflection coating of Si3N4 deposited on the ZrB2 coating leads to an increase in absorptance from 0.77 to 0.93, while the emittance remains unchanged.

Clinical relevance of ErbB-2/HER2 nuclear expression in breast cancer.

PubMed

Schillaci, Roxana; Guzmán, Pablo; Cayrol, Florencia; Beguelin, Wendy; Díaz Flaqué, María C; Proietti, Cecilia J; Pineda, Viviana; Palazzi, Jorge; Frahm, Isabel; Charreau, Eduardo H; Maronna, Esteban; Roa, Juan C; Elizalde, Patricia V

2012-02-22

The biological relevance of nuclear ErbB-2/HER2 (NuclErbB-2) presence in breast tumors remains unexplored. In this study we assessed the clinical significance of ErbB-2 nuclear localization in primary invasive breast cancer. The reporting recommendations for tumor marker prognostic studies (REMARK) guidelines were used as reference. Tissue microarrays from a cohort of 273 primary invasive breast carcinomas from women living in Chile, a Latin American country, were examined for membrane (MembErbB-2) and NuclErbB-2 expression by an immunofluorescence (IF) protocol we developed. ErbB-2 expression was also evaluated by immunohistochemistry (IHC) with a series of antibodies. Correlation between NuclErbB-2 and MembErbB-2, and between NuclErbB-2 and clinicopathological characteristics of tumors was studied. The prognostic value of NuclErbB-2 in overall survival (OS) was evaluated using Kaplan-Meier method, and Cox model was used to explore NuclErbB-2 as independent prognostic factor for OS. The IF protocol we developed showed significantly higher sensitivity for detection of NuclErbB-2 than IHC procedures, while its specificity and sensitivity to detect MembErbB-2 were comparable to those of IHC procedures. We found 33.6% NuclErbB-2 positivity, 14.2% MembErbB-2 overexpression by IF, and 13.0% MembErbB-2 prevalence by IHC in our cohort. We identified NuclErbB-2 positivity as a significant independent predictor of worse OS in patients with MembErbB-2 overexpression. NuclErbB-2 was also a biomarker of lower OS in tumors that overexpress MembErbB-2 and lack steroid hormone receptors. We revealed a novel role for NuclErbB-2 as an independent prognostic factor of poor clinical outcome in MembErbB-2-positive breast tumors. Our work indicates that patients presenting NuclErbB-2 may need new therapeutic strategies involving specific blockage of ErbB-2 nuclear migration.

A Computational Investigation of the Oxidative Deboronation of BoroGlycine, H2N–CH2–B(OH)2, Using H2O and H2O2

PubMed Central

Larkin, Joseph D.; Markham, George D.; Milkevitch, Matt; Brooks, Bernard R.; Bock, Charles W.

2014-01-01

We report results from a computational investigation of the oxidative deboronation of BoroGlycine, H2N–CH2–B(OH)2, using H2O and H2O2 as the reactive oxygen species (ROS) to yield aminomethanol, H2N–CH2–OH; these results complement our study on the protodeboronation of BoroGlycine to produce methylamine, H2N–CH3 (Larkin et al. J. Phys. Chem. A, 111, 6489–6500, 2007). Second-order Møller-Plesset (MP2) perturbation theory with Dunning-Woon correlation-consistent (cc) basis sets were used for the calculations with comparisons made to results from Density Functional Theory (DFT) at the PBE1PBE/6-311++G(d,p)(cc-pVDZ) levels. The effects of a bulk aqueous environment were also incorporated into the calculations employing PCM and CPCM methodology. Using H2O as the ROS, the reaction H2O + H2N–CH2–B(OH)2 → H2N–CH2–OH + H–B(OH)2 was calculated to be endothermic, the value of ΔH2980 was +12.0 kcal/mol at the MP2(FC)/cc-pVTZ computational level in vacuo and +13.7 kcal/mol in PCM aqueous media; the corresponding value for the activation barrier, ΔH‡, was +94.3 kcal/mol relative to the separated reactants in vacuo and +89.9 kcal/mol in PCM aqueous media. In contrast, the reaction H2O2 + H2N–CH2–B(OH)2 → H2N–CH2–OH + B(OH)3 was calculated to be highly exothermic with a ΔH2980 value of −100.9 kcal/mol at the MP2(FC)/cc-pVTZ computational level in vacuo and −99.6 kcal/mol in CPCM aqueous media; the highest-energy transition state for the multi-step process associated with this reaction involved the rearrangement of H2N–CH2–B(OH)(OOH) to H2N–CH2–O–B(OH)2 with a ΔH‡ value of +23.2 kcal/mol in vacuo relative to the separated reactants. These computational results for BoroGlycine are in accord with the experimental observations for the deboronation of the FDA approved anti-cancer drug Bortezomib (Velcade™, PS-341) where it was found to be the principle deactivation pathway. (Labutti et al. Chem. Res. Toxicol., 19, 539–546

30 CFR 250.1200 - Question index table.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Question index table. 250.1200 Section 250.1200... Measurement, Surface Commingling, and Security § 250.1200 Question index table. The table in this section...? § 250.1204(a) 20. What are the requirements for a periodic well test used for allocation? § 250.1204(b...

ORM-Based Semantics of B2B Transactions

NASA Astrophysics Data System (ADS)

Balsters, H.; van Blommestein, F.

After widespread implementation of Enterprise Resource Planning and Personal Information Management, the next wave in the application of ICT is headed towards business to business (B2B) communication. B2B has a number of specific aspects, one of them being negotiation. This aspect has been largely neglected by present implementations of standard EDI- or XML-messaging and by B2B webservice implementations. In this paper a precise model is given of the negotiation process. The requirements of a potential Buyer and the offer of a potential Seller are matched and, if the negotiation is successful, a contract is concluded. The negotiation process model is represented in ORM, extended with dynamic constraints. Our model may be implemented in the databases of the trading partners and in message- or service definitions.

Spinel, YbFe2O4, and Yb2Fe3O7 types of structure for compounds in the In2O3 and Sc2O3-A2O3-BO systems (A: Fe, Ga, or Al; B: Mg, Mn, Fe, Ni, Cu, or Zn) at temperatures over 1000C

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kimizuka, N.; Mohri, T.

In the Sc2O3-Ga2O3-CuO, Sc2O3-Ga2O3-ZnO, and Sc2O3-Al2O3-CuO systems, ScGaCuO4, ScGaZnO4, and ScAlCuO4 with the YbFe2O4-type structure and Sc2Ga2CuO7 with the Yb2Fe3O7-type structure were obtained. In the In2O3-A2O3-BO systems (A: Fe, Ga, or Al; B: Mg, Mn, Fe, Ni, or Zn), InGaFeO4, InGaNiO4, and InFeT MgO4 with the spinel structure, InGaZnO4, InGaMgO4, and InAl-CuO4 with the YbFe2O4-type structure, and In2Ga2MnO7 and In2Ga2ZnO7 with the Yb2Fe3O7-type structure were obtained. InGaMnO4 and InFe2O4 had both the YbFe2O4-type and spinel-type structures. The revised classification for the crystal structures of AB2O4 compounds is presented, based upon the coordination numbers of constituent A and B cations. 5more » references, 2 tables.« less

Electronic Commerce in Tourism in China: B2B or B2C?

NASA Astrophysics Data System (ADS)

Li, Hongxiu; Suomi, Reima

E-commerce has significantly changed the distribution channels of travel products in the world including China. Online channels are growing important in travel service distribution. In China tourism industry has been developed rapidly with the economic development, more and more international travel service providers are trying to expand their Chinese market through the Internet. This paper sheds lights on the e-commerce development models in China for international travel service providers. It explores the current e-tourism in China from the three different participants in the value chain in tourism industry - consumer, travel agent and travel service provider. The paper also identifies the barriers in B2C arena in international outbound travel market, and discusses the possible approaches for international travel service providers to develop their e-commerce in the huge Chinese market. The results in this study reveal that international travel service providers should focus on B2B model to expand their electronic market in China. B2C development in tourism largely depends on the change of Chinese customers' behavior and the change of international tourism regulations. The findings of the study are expected to assist international travel service providers to understand current e-tourism in China and to support their planning for future e-commerce development in China.

14 CFR Appendix B to Part 382 - Cross-Reference Table

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Cross-Reference Table B Appendix B to Part 382 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) SPECIAL REGULATIONS NONDISCRIMINATION ON THE BASIS OF DISABILITY IN AIR TRAVEL Pt. 382, App. B Appendix B...

14 CFR Appendix B to Part 382 - Cross-Reference Table

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Cross-Reference Table B Appendix B to Part 382 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) SPECIAL REGULATIONS NONDISCRIMINATION ON THE BASIS OF DISABILITY IN AIR TRAVEL Pt. 382, App. B Appendix B...

40 CFR Table 2 to Subpart Ooo of... - Known Organic Hazardous Air Pollutants (HAP) From the Manufacture of Amino/Phenolic Resins

Code of Federal Regulations, 2011 CFR

2011-07-01

... (HAP) From the Manufacture of Amino/Phenolic Resins 2 Table 2 to Subpart OOO of Part 63 Protection of... Pollutant Emissions: Manufacture of Amino/Phenolic Resins Pt. 63, Subpt. OOO, Table 2 Table 2 to Subpart OOO of Part 63—Known Organic Hazardous Air Pollutants (HAP) From the Manufacture of Amino/Phenolic Resins...

40 CFR Table 2 to Subpart Ooo of... - Known Organic Hazardous Air Pollutants (HAP) From the Manufacture of Amino/Phenolic Resins

Code of Federal Regulations, 2010 CFR

2010-07-01

... (HAP) From the Manufacture of Amino/Phenolic Resins 2 Table 2 to Subpart OOO of Part 63 Protection of... Pollutant Emissions: Manufacture of Amino/Phenolic Resins Pt. 63, Subpt. OOO, Table 2 Table 2 to Subpart OOO of Part 63—Known Organic Hazardous Air Pollutants (HAP) From the Manufacture of Amino/Phenolic Resins...

Thermal stability of hexagonal OsB2

NASA Astrophysics Data System (ADS)

Xie, Zhilin; Blair, Richard G.; Orlovskaya, Nina; Cullen, David A.; Andrew Payzant, E.

2014-11-01

The synthesis of novel hexagonal ReB2-type OsB2 ceramic powder was performed by high energy ball milling of elemental Os and B powders. Two different sources of B powder have been used for this mechanochemical synthesis. One B powder consisted of a mixture of amorphous and crystalline phases and a mixture of 10B and 11B isotopes with a fine particle size, while another B powder was a purely crystalline (rhombohedral) material consisting of enriched 11B isotope with coarse particle size. The same Os powder was used for the synthesis in both cases. It was established that, in the first case, the hexagonal OsB2 phase was the main product of synthesis with a small quantity of Os2B3 phase present after synthesis as an intermediate product. In the second case, where coarse crystalline 11B powder was used as a raw material, only Os2B3 boride was synthesized mechanochemically. The thermal stability of hexagonal OsB2 powder was studied by heating under argon up to 876 °C and cooling in vacuo down to -225 °C. During the heating, the sacrificial reaction 2OsB2+3O2→2Os+2B2O3 took place due to presence of O2/water vapor molecules in the heating chamber, resulting in the oxidation of B atoms and formation of B2O3 and precipitation of Os metal out of the OsB2 lattice. As a result of such phase changes during heating, the lattice parameters of hexagonal OsB2 changed significantly. The shrinkage of the a lattice parameter was recorded in 276-426 °C temperature range upon heating, which was attributed to the removal of B atoms from the OsB2 lattice due to oxidation followed by the precipitation of Os atoms and formation of Os metal. While significant structural changes occurred upon heating due to presence of O2, the hexagonal OsB2 ceramic demonstrated good phase stability upon cooling in vacuo with linear shrinkage of the lattice parameters and no phase changes detected during cooling.

30 CFR 250.1200 - Question index table.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Question index table. 250.1200 Section 250.1200... Security § 250.1200 Question index table. The table in this section lists questions concerning Oil and Gas... requirements for a periodic well test used for allocation? § 250.1204(b) 21. What are the requirements for site...

50 CFR Table 14b to Part 679 - Port of Landing Codes: Non-Alaska

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Port of Landing Codes: Non-Alaska 14b... ALASKA Pt. 679, Table 14b Table 14b to Part 679—Port of Landing Codes: Non-Alaska (California, Canada... report a landing at a location not currently assigned a location code number, use the code for “Other...

50 CFR Table 14b to Part 679 - Port of Landing Codes: Non-Alaska

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false Port of Landing Codes: Non-Alaska 14b... ALASKA Pt. 679, Table 14b Table 14b to Part 679—Port of Landing Codes: Non-Alaska (California, Canada... report a landing at a location not currently assigned a location code number, use the code for “Other...

Synaptotagmin C2B Domain Regulates Ca2+-triggered Fusion in Vitro

PubMed Central

Gaffaney, Jon D.; Dunning, F. Mark; Wang, Zhao; Hui, Enfu; Chapman, Edwin R.

2008-01-01

Synaptotagmin (syt) 1 is localized to synaptic vesicles, binds Ca2+, and regulates neuronal exocytosis. Syt 1 harbors two Ca2+-binding motifs referred to as C2A and C2B. In this study we examine the function of the isolated C2 domains of Syt 1 using a reconstituted, SNARE (soluble N-ethylmaleimide-sensitive factor attachment receptor)-mediated, fusion assay. We report that inclusion of phosphatidylethanolamine into reconstituted SNARE vesicles enabled isolated C2B, but not C2A, to regulate Ca2+-triggered fusion. The isolated C2B domain had a 6-fold lower EC for Ca2+ 50-activated fusion than the intact cytosolic domain of Syt 1 (C2AB). Phosphatidylethanolamine increased both the rate and efficiency of C2AB- and C2B-regulated fusion without affecting their abilities to bind membrane-embedded syntaxin-SNAP-25 (t-SNARE) complexes. At equimolar concentrations, the isolated C2A domain was an effective inhibitor of C2B-, but not C2AB-regulated fusion; hence, C2A has markedly different effects in the fusion assay depending on whether it is tethered to C2B. Finally, scanning alanine mutagenesis of C2AB revealed four distinct groups of mutations within the C2B domain that play roles in the regulation of SNARE-mediated fusion. Surprisingly, substitution of Arg-398 with alanine, which lies on the opposite end of C2B from the Ca2+/membrane-binding loops, decreases C2AB t-SNARE binding and Ca2+-triggered fusion in vitro without affecting Ca2+-triggered interactions with phosphatidylserine or vesicle aggregation. In addition, some mutations uncouple the clamping and stimulatory functions of syt 1, suggesting that these two activities are mediated by distinct structural determinants in C2B. PMID:18784080

40 CFR Table 2 to Subpart Eeee of... - Operating Limits for Incinerators and Wet Scrubbers

Code of Federal Regulations, 2010 CFR

2010-07-01

... Wet Scrubbers 2 Table 2 to Subpart EEEE of Part 60 Protection of Environment ENVIRONMENTAL PROTECTION... Scrubbers As stated in § 60.2916, you must comply with the following: For these operatingparameters You must...-hour rolling for continuous and intermittent units a. 2. Pressure drop across the wet scrubber or...

40 CFR Table 2 to Subpart Eeee of... - Operating Limits for Incinerators and Wet Scrubbers

Code of Federal Regulations, 2011 CFR

2011-07-01

... Wet Scrubbers 2 Table 2 to Subpart EEEE of Part 60 Protection of Environment ENVIRONMENTAL PROTECTION... Scrubbers As stated in § 60.2916, you must comply with the following: For these operatingparameters You must...-hour rolling for continuous and intermittent units a. 2. Pressure drop across the wet scrubber or...

LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling

PubMed Central

2013-01-01

Introduction Lysyl oxidase-like 2 (LOXL2) is a matrix-remodeling enzyme that has been shown to play a key role in invasion and metastasis of breast carcinoma cells. However, very little is known about its role in normal tissue homeostasis. Here, we investigated the effects of LOXL2 expression in normal mammary epithelial cells to gain insight into how LOXL2 mediates cancer progression. Methods LOXL2 was expressed in MCF10A normal human mammary epithelial cells. The 3D acinar morphogenesis of these cells was assessed, as well as the ability of the cells to form branching structures on extracellular matrix (ECM)-coated surfaces. Transwell-invasion assays were used to assess the invasive properties of the cells. Clinically relevant inhibitors of ErbB2, lapatinib and Herceptin (traztuzumab), were used to investigate the role of ErbB2 signaling in this model. A retrospective study on a previously published breast cancer patient dataset was carried out by using Disease Specific Genomic Analysis (DSGA) to investigate the correlation of LOXL2 mRNA expression level with metastasis and survival of ErbB2-positive breast cancer patients. Results Fluorescence staining of the acini revealed increased proliferation, decreased apoptosis, and disrupted polarity, leading to abnormal lumen formation in response to LOXL2 expression in MCF10A cells. When plated onto ECM, the LOXL2-expressing cells formed branching structures and displayed increased invasion. We noted that LOXL2 induced ErbB2 activation through reactive oxygen species (ROS) production, and ErbB2 inhibition by using Herceptin or lapatinib abrogated the effects of LOXL2 on MCF10A cells. Finally, we found LOXL2 expression to be correlated with decreased overall survival and metastasis-free survival in breast cancer patients with ErbB2-positive tumors. Conclusions These findings suggest that LOXL2 expression in normal epithelial cells can induce abnormal changes that resemble oncogenic transformation and cancer progression

Possible involvement of nuclear factor erythroid 2-related factor 2 in the gene expression of Cyp2b10 and Cyp2a5☆

PubMed Central

Ashino, Takashi; Ohkubo-Morita, Haruyo; Yamamoto, Masayuki; Yoshida, Takemi; Numazawa, Satoshi

2014-01-01

Cytochrome P450 gene expression is altered by various chemical compounds. In this study, we used nuclear factor erythroid 2-related factor 2 (Nrf2)–deficient (Nrf2−⧸−) mice to investigate the involvement of Nrf2 in Cyp2b10 and Cyp2a5 gene expression. Phorone, an Nrf2 activator, strongly increased Cyp2b10 and Cyp2a5 mRNA as well as Nrf2 target genes, including NAD(P)H-quinone oxidoreductase-1 and heme oxygenase-1, in wild-type mouse livers 8 h after treatment. The phorone-induced mRNA levels in Nrf2−⧸− mouse livers were lower than that in wild-type mouse livers. Nrf2−⧸− mice showed attenuated Cyp2b10 and Cyp2a5 induction by phenobarbital, a classical Cyp2b inducer. These findings suggest that the Nrf2 pathway is involved in Cyp2b10 and Cyp2a5 gene expression. PMID:24494203

A Fast Healthcare Interoperability Resources (FHIR) layer implemented over i2b2.

PubMed

Boussadi, Abdelali; Zapletal, Eric

2017-08-14

Standards and technical specifications have been developed to define how the information contained in Electronic Health Records (EHRs) should be structured, semantically described, and communicated. Current trends rely on differentiating the representation of data instances from the definition of clinical information models. The dual model approach, which combines a reference model (RM) and a clinical information model (CIM), sets in practice this software design pattern. The most recent initiative, proposed by HL7, is called Fast Health Interoperability Resources (FHIR). The aim of our study was to investigate the feasibility of applying the FHIR standard to modeling and exposing EHR data of the Georges Pompidou European Hospital (HEGP) integrating biology and the bedside (i2b2) clinical data warehouse (CDW). We implemented a FHIR server over i2b2 to expose EHR data in relation with five FHIR resources: DiagnosisReport, MedicationOrder, Patient, Encounter, and Medication. The architecture of the server combines a Data Access Object design pattern and FHIR resource providers, implemented using the Java HAPI FHIR API. Two types of queries were tested: query type #1 requests the server to display DiagnosticReport resources, for which the diagnosis code is equal to a given ICD-10 code. A total of 80 DiagnosticReport resources, corresponding to 36 patients, were displayed. Query type #2, requests the server to display MedicationOrder, for which the FHIR Medication identification code is equal to a given code expressed in a French coding system. A total of 503 MedicationOrder resources, corresponding to 290 patients, were displayed. Results were validated by manually comparing the results of each request to the results displayed by an ad-hoc SQL query. We showed the feasibility of implementing a Java layer over the i2b2 database model to expose data of the CDW as a set of FHIR resources. An important part of this work was the structural and semantic mapping between the

26 CFR 31.3406(b)(2)-2 - Original issue discount.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 26 Internal Revenue 15 2010-04-01 2010-04-01 false Original issue discount. 31.3406(b)(2)-2... SOURCE Collection of Income Tax at Source § 31.3406(b)(2)-2 Original issue discount. (a) Original issue discount subject to backup withholding. The amount of original issue discount, treated as interest, subject...

Emergence of canine parvovirus subtype 2b (CPV-2b) infections in Australian dogs.

PubMed

Clark, Nicholas J; Seddon, Jennifer M; Kyaw-Tanner, Myat; Al-Alawneh, John; Harper, Gavin; McDonagh, Phillip; Meers, Joanne

2018-03-01

Tracing the temporal dynamics of pathogens is crucial for developing strategies to detect and limit disease emergence. Canine parvovirus (CPV-2) is an enteric virus causing morbidity and mortality in dogs around the globe. Previous work in Australia reported that the majority of cases were associated with the CPV-2a subtype, an unexpected finding since CPV-2a was rapidly replaced by another subtype (CPV-2b) in many countries. Using a nine-year dataset of CPV-2 infections from 396 dogs sampled across Australia, we assessed the population dynamics and molecular epidemiology of circulating CPV-2 subtypes. Bayesian phylogenetic Skygrid models and logistic regressions were used to trace the temporal dynamics of CPV-2 infections in dogs sampled from 2007 to 2016. Phylogenetic models indicated that CPV-2a likely emerged in Australia between 1973 and 1988, while CPV-2b likely emerged between 1985 and 1998. Sequences from both subtypes were found in dogs across continental Australia and Tasmania, with no apparent effect of climate variability on subtype occurrence. Both variant subtypes exhibited a classical disease emergence pattern of relatively high rates of evolution during early emergence followed by subsequent decreases in evolutionary rates over time. However, the CPV-2b subtype maintained higher mutation rates than CPV-2a and continued to expand, resulting in an increase in the probability that dogs will carry this subtype over time. Ongoing monitoring programs that provide molecular epidemiology surveillance will be necessary to detect emergence of new variants and make informed recommendations to develop reliable detection and vaccine methods. Copyright © 2017 Elsevier B.V. All rights reserved.

40 CFR Table 9 to Subpart Uuuuu of... - Applicability of General Provisions to Subpart UUUUU

Code of Federal Regulations, 2013 CFR

2013-07-01

...-Fired Electric Utility Steam Generating Units Pt. 63, Subpt. UUUUU, Table 9 Table 9 to Subpart UUUUU of... Review and Notification Requirements Yes. § 63.6(a), (b)(1)-(b)(5), (b)(7), (c), (f)(2)-(3), (g), (h)(2...

40 CFR Table 9 to Subpart Uuuuu of... - Applicability of General Provisions to Subpart UUUUU

Code of Federal Regulations, 2014 CFR

2014-07-01

...-Fired Electric Utility Steam Generating Units Pt. 63, Subpt. UUUUU, Table 9 Table 9 to Subpart UUUUU of... Review and Notification Requirements Yes. § 63.6(a), (b)(1)-(b)(5), (b)(7), (c), (f)(2)-(3), (g), (h)(2...

40 CFR Table 9 to Subpart Uuuuu of... - Applicability of General Provisions to Subpart UUUUU

Code of Federal Regulations, 2012 CFR

2012-07-01

...-Fired Electric Utility Steam Generating Units Pt. 63, Subpt. UUUUU, Table 9 Table 9 to Subpart UUUUU of... Review and Notification Requirements Yes. § 63.6(a), (b)(1)-(b)(5), (b)(7), (c), (f)(2)-(3), (g), (h)(2...

Mutations in the PP2A regulatory subunit B family genes PPP2R5B, PPP2R5C and PPP2R5D cause human overgrowth.

PubMed

Loveday, Chey; Tatton-Brown, Katrina; Clarke, Matthew; Westwood, Isaac; Renwick, Anthony; Ramsay, Emma; Nemeth, Andrea; Campbell, Jennifer; Joss, Shelagh; Gardner, McKinlay; Zachariou, Anna; Elliott, Anna; Ruark, Elise; van Montfort, Rob; Rahman, Nazneen

2015-09-01

Overgrowth syndromes comprise a group of heterogeneous disorders characterised by excessive growth parameters, often in association with intellectual disability. To identify new causes of human overgrowth, we have been undertaking trio-based exome sequencing studies in overgrowth patients and their unaffected parents. Prioritisation of functionally relevant genes with multiple unique de novo mutations revealed four mutations in protein phosphatase 2A (PP2A) regulatory subunit B family genes protein phosphatase 2, regulatory Subunit B', beta (PPP2R5B); protein phosphatase 2, regulatory Subunit B', gamma (PPP2R5C); and protein phosphatase 2, regulatory Subunit B', delta (PPP2R5D). This observation in 3 related genes in 111 individuals with a similar phenotype is greatly in excess of the expected number, as determined from gene-specific de novo mutation rates (P = 1.43 × 10(-10)). Analysis of exome-sequencing data from a follow-up series of overgrowth probands identified a further pathogenic mutation, bringing the total number of affected individuals to 5. Heterozygotes shared similar phenotypic features including increased height, increased head circumference and intellectual disability. The mutations clustered within a region of nine amino acid residues in the aligned protein sequences (P = 1.6 × 10(-5)). We mapped the mutations onto the crystal structure of the PP2A holoenzyme complex to predict their molecular and functional consequences. These studies suggest that the mutations may affect substrate binding, thus perturbing the ability of PP2A to dephosphorylate particular protein substrates. PP2A is a major negative regulator of v-akt murine thymoma viral oncogene homolog 1 (AKT). Thus, our data further expand the list of genes encoding components of the phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K)/AKT signalling cascade that are disrupted in human overgrowth conditions. © The Author 2015. Published by Oxford University Press.

Demagnetization of Nd 2Fe 14B, Pr 2Fe 14B, and Sm 2Co 17 Permanent Magnets in Spallation Irradiation Fields

DOE PAGES

Simos, Nikolaos; Ozaki, S.; Mokhov, N.; ...

2018-02-27

Prompted by the need for radiation-resistant permanent magnets for insertion devices (IDs) of high-brilliance next-generation synchrotrons such as the National Synchrotron Light Source II, the demagnetization of Nd 2Fe 14B and Pr 2Fe 14B was studied after exposure to a mixed irradiating field. Degradation and damage of the permanent magnetic material by components of electromagnetic showers induced in magnets by intense high-energy electron beams will alter the magnetic field structure of the IDs. Plate-like Nd 2Fe 14B magnets were irradiated to 1.8 Grad dose and were evaluated against Pr 2Fe 14B magnets irradiated to a lower dose of 20 Mrad.more » In addition, annular Sm 2Co 17 and Nd 2Fe 14B magnets integrated within a ferrofluidic feedthrough (FFFT) rotary seal were also irradiated to dose levels of 2 Grad for Sm 2Co 17 and 20 Mrad for Nd 2Fe 14B. Post-irradiation measurements of the magnetic intensity revealed that severe demagnetization exceeding 85% occurs in Nd 2Fe 14B magnets after only 50 Mrad dose and over 87% for Pr 2Fe 14B after 10 Mrad dose. The annular-shaped Sm 2Co 17 magnets of the FFFTs were almost insensitive to irradiation up to a dose of 2 Grad. Annular-shaped Nd 2Fe 14B magnets also showed resistance to demagnetization, a direct consequence of the annular shape which is characterized by the removal of the stronger demagnetizing field present at the center of a disk-like magnet. As a result, the sensitivity of boron-based permanent magnets to neutron energy (thermal versus fast) was also assessed via specifically designed experiments and discussed.« less

Demagnetization of Nd 2Fe 14B, Pr 2Fe 14B, and Sm 2Co 17 Permanent Magnets in Spallation Irradiation Fields

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simos, Nikolaos; Ozaki, S.; Mokhov, N.

Prompted by the need for radiation-resistant permanent magnets for insertion devices (IDs) of high-brilliance next-generation synchrotrons such as the National Synchrotron Light Source II, the demagnetization of Nd 2Fe 14B and Pr 2Fe 14B was studied after exposure to a mixed irradiating field. Degradation and damage of the permanent magnetic material by components of electromagnetic showers induced in magnets by intense high-energy electron beams will alter the magnetic field structure of the IDs. Plate-like Nd 2Fe 14B magnets were irradiated to 1.8 Grad dose and were evaluated against Pr 2Fe 14B magnets irradiated to a lower dose of 20 Mrad.more » In addition, annular Sm 2Co 17 and Nd 2Fe 14B magnets integrated within a ferrofluidic feedthrough (FFFT) rotary seal were also irradiated to dose levels of 2 Grad for Sm 2Co 17 and 20 Mrad for Nd 2Fe 14B. Post-irradiation measurements of the magnetic intensity revealed that severe demagnetization exceeding 85% occurs in Nd 2Fe 14B magnets after only 50 Mrad dose and over 87% for Pr 2Fe 14B after 10 Mrad dose. The annular-shaped Sm 2Co 17 magnets of the FFFTs were almost insensitive to irradiation up to a dose of 2 Grad. Annular-shaped Nd 2Fe 14B magnets also showed resistance to demagnetization, a direct consequence of the annular shape which is characterized by the removal of the stronger demagnetizing field present at the center of a disk-like magnet. As a result, the sensitivity of boron-based permanent magnets to neutron energy (thermal versus fast) was also assessed via specifically designed experiments and discussed.« less

Electronic and elastic properties of new semiconducting oP(12)-type RuB(2) and OsB(2).

PubMed

Hao, Xianfeng; Xu, Yuanhui; Gao, Faming

2011-03-30

Using first-principles total energy calculations we investigate the structural, elastic and electronic properties of new hypothetical oP(12)-type phase RuB(2) and OsB(2). The calculations indicate that the oP(12)-type phase RuB(2) and OsB(2) are thermodynamically and mechanically stable. Remarkably, the new phases RuB(2) and OsB(2) are predicted to be semiconductors, and the appearance of band gaps is ascribed to the enhanced B-B covalent hybridization. Compared to metallic oP(6)-type RuB(2) and OsB(2) phases, the new phases possess similar mechanical properties and hardness. The combination of the probability of tunable electronic properties, strong stiffness and high hardness make RuB(2) and OsB(2) attractive and interesting for advanced applications. © 2011 IOP Publishing Ltd

Peginterferon Alfa-2b (PEG-Intron)

MedlinePlus

Peginterferon alfa-2b is used alone or in combination with ribavirin (a medication) to treat chronic (long-term) hepatitis ... treated with interferon alpha (medication similar to peginterferon alfa-2b) in the past. Peginterferon alfa-2b is ...

A new superhard material: Osmium diboride OsB 2

NASA Astrophysics Data System (ADS)

Hebbache, M.; Stuparević, L.; Živković, D.

2006-08-01

Superhard materials have many industrial applications, wherever resistance to abrasion and wear are important. The synthesis of new superhard materials is one of the great challenges to scientists. We re-examined the phase diagram of the binary osmium-boron system and confirmed the existence of two hexagonal phases, OsB 1.1, Os 2B 3, and an orthorhombic phase, OsB 2. Almost nothing is known about the physical properties of osmium borides. Microhardness measurements show that OsB 2 is extremely hard. Ab initio calculations show that this is due to formation of covalent bonds between boron atoms. OsB 2 is also a low compressibility material. It can be used as hard coating.

K2-141 b. A 5-M⊕ super-Earth transiting a K7 V star every 6.7 h

NASA Astrophysics Data System (ADS)

Barragán, O.; Gandolfi, D.; Dai, F.; Livingston, J.; Persson, C. M.; Hirano, T.; Narita, N.; Csizmadia, Sz.; Winn, J. N.; Nespral, D.; Prieto-Arranz, J.; Smith, A. M. S.; Nowak, G.; Albrecht, S.; Antoniciello, G.; Bo Justesen, A.; Cabrera, J.; Cochran, W. D.; Deeg, H.; Eigmuller, Ph.; Endl, M.; Erikson, A.; Fridlund, M.; Fukui, A.; Grziwa, S.; Guenther, E.; Hatzes, A. P.; Hidalgo, D.; Johnson, M. C.; Korth, J.; Palle, E.; Patzold, M.; Rauer, H.; Tanaka, Y.; Van Eylen, V.

2018-05-01

We report on the discovery of K2-141 b (EPIC 246393474 b), an ultra-short-period super-Earth on a 6.7 h orbit transiting an active K7 V star based on data from K2 campaign 12. We confirmed the planet's existence and measured its mass with a series of follow-up observations: seeing-limited MuSCAT imaging, NESSI high-resolution speckle observations, and FIES and HARPS high-precision radial-velocity monitoring. K2-141 b has a mass of 5.31 ± 0.46 M⊕ and radius of 1.54-0.09+0.10 R⊕, yielding a mean density of 8.00-1.45+1.83 g cm-3 and suggesting a rocky-iron composition. Models indicate that iron cannot exceed 70% of the total mass. With an orbital period of only 6.7 h, K2-141 b is the shortest-period planet known to date with a precisely determined mass. Based on observations obtained with (a) the Nordic Optical Telescope (NOT), operated on the island of La Palma jointly by Denmark, Finland, Iceland, Norway, and Sweden, in the Spanish Observatorio del Roque de los Muchachos (ORM) of the Instituto de Astrofisica de Canarias (IAC); (b) the 3.6m ESO telescope at La Silla Observatory under program ID 099.C-0491; (c) the Kepler space telescope in its extended mission K2.Tables of the light curve data and the radial velocities are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/612/A95

Destabilization of B2 RNA by EZH2 activates the stress response

PubMed Central

Zovoilis, Athanasios; Cifuentes-Rojas, Catherine; Chu, Hsueh-Ping; Hernandez, Alfredo J.; Lee, Jeannie T.

2017-01-01

SUMMARY More than 98% of the mammalian genome is noncoding and interspersed transposable elements account for ~50% of noncoding space. Here, we demonstrate that a specific interaction between the Polycomb protein, EZH2, and RNA made from B2 SINE retrotransposons controls stress-responsive genes in mouse cells. In the heat shock model, B2 RNA binds stress genes and suppresses their transcription. Upon stress, EZH2 is recruited and triggers cleavage of B2 RNA. B2 degradation in turn upregulates stress genes. Evidence indicates that B2 RNA operates as “speed bump” against advancement of RNA Polymerase II, and temperature stress releases the brakes on transcriptional elongation. These data attribute a new function to EZH2 that is independent of its histone methyltransferase activity and reconcile how EZH2 can be associated with both gene repression and activation. Our study reveals that EZH2 and B2 together control activation of a large network of genes involved in thermal stress. PMID:27984727

Determination of aflatoxins B1, B2, G1 and G2 in spices using a multifunctional column clean-up.

PubMed

Akiyama, H; Goda, Y; Tanaka, T; Toyoda, M

2001-10-12

A rapid and simple method using a multifunctional column, which contains lipophilic and charged active sites, was developed to analyse aflatoxins B1, B2, G1 and G2 in various spices, such as red pepper and nutmeg. After extraction by acetonitrile:water (9:1) and clean-up using MultiSep #228 column, the aflatoxins and aflatoxin-TFA derivatives are determined using LC with fluorescence detection. Recoveries of each aflatoxin B1, B2, G1 and G2 spiked to red pepper, white pepper, black pepper, nutmeg and tear grass at the level of 10 ng/g were over 80-85% in all instances. The minimum detectable concentration for aflatoxins in red pepper was 0.5 ng/g.

7 CFR 1b.2 - Policy.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 1 2013-01-01 2013-01-01 false Policy. 1b.2 Section 1b.2 Agriculture Office of the Secretary of Agriculture NATIONAL ENVIRONMENTAL POLICY ACT § 1b.2 Policy. (a) All policies and programs of... environment for present and future generations. (b) Each USDA agency is responsible for compliance with this...

7 CFR 1b.2 - Policy.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 1 2010-01-01 2010-01-01 false Policy. 1b.2 Section 1b.2 Agriculture Office of the Secretary of Agriculture NATIONAL ENVIRONMENTAL POLICY ACT § 1b.2 Policy. (a) All policies and programs of... environment for present and future generations. (b) Each USDA agency is responsible for compliance with this...

The real factor for polypeptide elongation in Dictyostelium cells is EF-2B, not EF-2A

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yoshino, Tomoko; Maeda, Yasuo; Amagai, Aiko

2007-08-03

Polypeptide elongation factor 2 (EF-2) plays an essential role in protein synthesis and is believed to be indispensable for cell proliferation. Recently, it has been demonstrated that there are two kinds of EF-2 (EF-2A and EF-2B with 76.6% of sequence identity at the amino acid level) in Dictyostelium discoideum. Although the knockout of EF-2A slightly impaired cytokinesis, EF-2A null cells exhibited almost normal protein synthesis and cell growth, suggesting that there is another molecule capable of compensating for EF-2 function. Since EF-2B is the most likely candidate, we examined its function using ef-2b knockdown cells prepared by the RNAi method.more » Our results strongly suggest that EF-2B is required for protein synthesis and cell proliferation, functioning as the real EF-2. Interestingly, the expressions of ef-2a and ef-2b mRNAs during development are reversely regulated, and the ef-2b expression is greatly augmented in ef-2a null cells.« less

Oxidation Resistance, Electrical and Thermal Conductivity, and Spectral Emittance of Fully Dense HfB2 and ZrB2 with SiC, TaSi2, and LaB6 Additives

DTIC Science & Technology

2012-01-26

Resistance , Electrical and Thermal Conductivity, and Spectral Emittance of Fully Dense HfB2 and ZrB2 "With SiC, TaSi2, and LaB6 Additives Sb. GRANT NUMBER... RESISTANCE , ELECTRICAL AND THERMAL CONDUCTIVITY, AND SPECTRAL EMITTANCE OF FULLY DENSE HfB2 AND ZrB2 WITH SiC, TaSi2, AND LaB6 ADDITIVES Air Force Office...thickened regions with dry 220 grit SiC sandpaper so that a low- resistance electrical connection could be achieved. A handheld multimeter was used to measure

Impacts of Blast-Induced Traumatic Brain Injury on Expressions of Hepatic Cytochrome P450 1A2, 2B1, 2D1, and 3A2 in Rats.

PubMed

Ma, Jie; Wang, Junrui; Cheng, Jingmin; Xiao, Wenjing; Fan, Kaihua; Gu, Jianwen; Yu, Botao; Yin, Guangfu; Wu, Juan; Ren, Jiandong; Hou, Jun; Jiang, Yan; Tan, Yonghong; Jin, Weihua

2017-01-01

The hepatic cytochrome P450 (CYP450) enzyme superfamily is one of the most important drug-metabolizing enzyme systems, which is responsible for the metabolism of a large number of clinically relevant medications used in traumatic brain injury (TBI) therapy. Modification of CYP450 expression may have important influences on drug metabolism and lead to untoward effects on those with narrow therapeutic windows. However, the impact of blast-induced TBI (bTBI) on the expression of CYP450 has received little attention. The subfamilies of CYP1A, 2B, 2D, and 3A account for about 85 % of all human drug metabolism of clinical significance. Therefore, in this study, we investigated the expressions of hepatic CYP1A2, CYP2B1, CYP2D1, and CYP3A2 in rats suffering bTBI. Meanwhile, we also measured some important cytokines in serum after injury, and calculated the correlation between these cytokines and the expressions of CYP1A2, CYP2B1, CYP2D1, and CYP3A2. The results showed that bTBI could significantly reduce mRNA expressions of CYP1A2, CYP2D1, and CYP3A2 at the early stage and induce the expressions from 48 h to 1 week after injury. The protein expressions of these CYP450s had all been downregulated from 24 to 48 h post- injury, and then began to elevate at 48 h after bTBI. The cytokines, IL-1β, IL-2, IL-6, and TNF-α, increased significantly in the early phase, and began to reduce at the delayed phase of bTBI. The serum levels of IL-1β, IL-6, and TNF-α but not IL-2 were significantly negative correlated with the mRNA expressions of CYP2B1 and CYP2D1 and the proteins expressions of CYP1A2, CYP2B1, CYP2D1, and CYP3A2. In conclusion, our work has, for the first time, indicated that bTBI has significant impact on the expressions of CYP1A2, CYP2B1, CYP2D1, and CYP3A2, which may be related to the cytokines induced by the injury.

Exact one-sided confidence bounds for the risk ratio in 2 x 2 tables with structural zero.

PubMed

Lloyd, Chris J; Moldovan, Max V

2007-12-01

This paper examines exact one-sided confidence limits for the risk ratio in a 2 x 2 table with structural zero. Starting with four approximate lower and upper limits, we adjust each using the algorithm of Buehler (1957) to arrive at lower (upper) limits that have exact coverage properties and are as large (small) as possible subject to coverage, as well as an ordering, constraint. Different Buehler limits are compared by their mean size, since all are exact in their coverage. Buehler limits based on the signed root likelihood ratio statistic are found to have the best performance and recommended for practical use. (c) 2007 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Mutational Analysis of the Stability of the H2A and H2B Histone Monomers

PubMed Central

Stump, Matthew R.; Gloss, Lisa M.

2008-01-01

The eukaryotic histone heterodimer H2A-H2B folds through an obligatory dimeric intermediate that forms in a nearly diffusion-limited association reaction in the stopped-flow dead time. It is unclear whether there is partial folding of the isolated monomers before association. To address the possible contributions of structure in the monomers to the rapid association, we characterized H2A and H2B monomers in the absence of their heterodimeric partner. By far-UV circular dichroism, the H2A and H2B monomers are 15% and 31% helical, respectively—significantly less than observed in X-ray crystal structures. Acrylamide quenching of the intrinsic Tyr fluorescence was indicative of tertiary structure. The H2A and H2B monomers exhibit free energies of unfolding of 2.5 and 2.9 kcal mol−1, respectively; at 10 μM, the sum of the stability of the monomers is ~60% of the stability of the native dimer. The helical content, stability and m values indicate that H2B has a more stable, compact structure than H2A. The monomer m values are larger than expected for the extended histone fold motif, suggesting that the monomers adopt an overly-collapsed structure. Stopped-flow refolding—initiated from urea-denatured monomers or the partially folded monomers populated at low denaturant concentrations—yielded essentially identical rates, indicating that monomer folding is productive in the rapid association and folding of the heterodimer. A series of Ala and Gly mutations were introduced into H2A and H2B to probe the importance of helix propensity on the structure and stability of the monomers. The mutational studies show that the central α-helix of the histone fold, which makes extensive inter-monomer contacts, is structured in H2B but only partially folded in H2A. PMID:18976667

Magnetic Ordering of Antiferromagnetic Trimer System 2b·3CuCl2·2H2O

NASA Astrophysics Data System (ADS)

Sanda, M.; Kubo, K.; Asano, T.; Morodomi, H.; Inagaki, Y.; Kawae, T.; Wang, J.; Matsuo, A.; Kindo, K.; Sato, T. J.

2012-12-01

In this paper, we present the magnetic properties of 2b·3CuCl2·2H2O (b = betaine, C5H11NO2). 2b·3CuCl2·2H2O is the first model substance for a two-dimensional S = 1/2 orthogonal antiferromagnetic trimer system. We have performed magnetic susceptibility, magnetization curve, and specific heat under extreme conditions: low temperatures and high magnetic fields in this system. The experimental results indicate that this substance is a magnetically S = 1/2 antiferromagnetic trimer system. The magnetization also shows one-third of the saturation value (MS ~ 3.2μB/f.u.) between 5 and 14T The specific heat in a zero field shows a sharp peak at 1.38K corresponding to a long-range magnetic ordering, TN. As the magnetic field increases, the TN shifts remarkably to a lower temperature and is suppressed. Above 5T, the specific heat has no anomaly down to 150mK In the plateau region with an energy gap, the magnetic ordering seems to be disappeared.

Experiences and Future Expectations towards Online Courses--An Empirical Study of the B2C-and B2B-Segments

ERIC Educational Resources Information Center

Krämer, Andreas; Böhrs, Sandra

2016-01-01

This article explores the future potential for the development of online courses. The findings are based on an empirical study with 3 sample groups: (1) B2C segment in Germany, (2) B2C segment in the United States, and (3) B2B segment (international). In the first step the status quo of the use of e-learning in general and online courses in…

Detection of amino acetonitrile in Sgr B2(N)

NASA Astrophysics Data System (ADS)

Belloche, A.; Menten, K. M.; Comito, C.; Müller, H. S. P.; Schilke, P.; Ott, J.; Thorwirth, S.; Hieret, C.

2008-04-01

toward Sgr B2, with column-density upper limits of 6 × 1015 and 3 × 1012-14 cm-2, respectively. Conclusions: Based on our amino acetonitrile detection toward Sgr B2(N) and a comparison to the pair methylcyanide/acetic acid both detected in this source, we suggest that the column density of both glycine conformers in Sgr B2(N) is well below the best upper limits published recently by other authors, and probably below the confusion limit in the 1-3 mm range. Based on observations carried out with the IRAM Plateau de Bure Interferometer, the IRAM 30 m telescope, the Australia Telescope Compact Array, and the NRAO Very Large Array. IRAM is supported by INSU/CNRS (France), MPG (Germany) and IGN (Spain). The Australia Telescope Compact Array is part of the Australia Telescope which is funded by the Commonwealth of Australia for operation as a National Facility managed by CSIRO. The National Radio Astronomy Observatory is a facility of the National Science Foundation operated under cooperative agreement by Associated Universities, Inc. Table [see full textsee full text] and Fig. [see full textsee full text] are only available in electronic form at http://www.aanda.org The calibrated and deconvolved data cubes and images (line and continuum) obtained with the PdBI, the ATCA, and the VLA are available in FITS format at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsweb.u-strasbg.fr/cgi-bin/qcat?J/A+A/482/179

A Cross-Talk Between NFAT and NF-κB Pathways is Crucial for Nickel-Induced COX-2 Expression in Beas-2B Cells

PubMed Central

Cai, T.; Li, X.; Ding, J.; Luo, W.; Li, J.; Huang, C.

2013-01-01

Cyclooxygenase-2 (COX-2) is a critical enzyme implicated in chronic inflammation-associated cancer development. Our studies have shown that the exposure of Beas-2B cells, a human bronchial epithelial cell line, to lung carcinogenic nickel compounds results in increased COX-2 expression. However, the signaling pathways leading to nickel-induced COX-2 expression are not well understood. In the current study, we found that the exposure of Beas-2B cells to nickel compounds resulted in the activation of both nuclear factor of activated T cell (NFAT) and nuclear factor-κB (NF-κB). The expression of COX-2 induced upon nickel exposure was inhibited by either a NFAT pharmacological inhibitor or the knockdown of NFAT3 by specific siRNA. We further found that the activation of NFAT and NF-κB was dependent on each other. Since our previous studies have shown that NF-κB activation is critical for nickel-induced COX-2 expression in Beas-2B cells exposed to nickel compounds under same experimental condition, we anticipate that there might be a cross-talk between the activation of NFAT and NF-κB for the COX-2 induction due to nickel exposure in Beas-2B cells. Furthermore, we showed that the scavenging of reactive oxygen species (ROS) by introduction of mitochondrial catalase inhibited the activation of both NFAT and NF-κB, and the induction of COX-2 due to nickel exposure. Taken together, our results defining the evidence showing a key role of the cross-talk between NFAT and NF-κB pathways in regulating nickel-induced COX-2 expression, further provide insight into the understanding of the molecular mechanisms linking nickel exposure to its lung carcinogenic effects. PMID:21486220

Interpretation of diagnostic data: 3. How to do it with a simple table (part B).

PubMed

1983-10-01

The following guidelines are useful if you want to "do it with a simple table" (Table IV): First, identify the sensitivity and specificity of the sign, symptom or diagnostic test you plan to use. Many are already in the literature, and subspecialists should either know them for their field or be able to track them down for you. Depending on whether you are considering a sign, a symptom or a diagnostic laboratory test, you will want to track down a clinical subspecialist, a radiologist, a pathologist and so on. Start your table with a total of 1000 patients, as shown in location (a + b + c + d) of panel A. Using the information you have about the patient before you apply the diagnostic test, estimate the patient's pretest likelihood (prevalence or prior probability) of the target disorder -- let's say 10%. Take this proportion of the total (100) and place it in location (a + c); the remaining 900 patients go in location (b + d) (panel B). Multiply (a + c) (100) by the sensitivity of the diagnostic test (let's say 83%) and place the result (83) in cell a and the difference (17) in cell c; similarly, multiply (b + d) (900) by the specificity of the diagnostic test (let's say 91%) and place the result (819) in cell d and the difference (81) in cell b (panel C). If (a + b) and (c + d) do not add up to 1000, you will know you have made a mistake. You can now calculate the positive predictive value, a/(a + b), and the negative predictive value, d/(c + d), as shown in panel D. You have now reached a level of understanding a fair bit beyond the rule-in/rule-out strategy discussed in part 1 of our series. Furthermore, you can already do more than most clinicians, so you may want to stop here, at least for a while. On the other hand, you may want to go further and learn how to handle slightly more complex tables with multiple cut-off points. In the next article you will find more powerful ways to take advantage of the degree of positivity and negativity of diagnostic test

Kinetic analysis of MgB2 layer formation in advanced internal magnesium infiltration (AIMI) processed MgB2 wires

PubMed Central

Li, G. Z.; Sumption, M. D.; Collings, E. W.

2015-01-01

Significantly enhanced critical current density (Jc) for MgB2 superconducting wires can be obtained following the advanced internal Mg infiltration (AIMI) route. But unless suitable precautions are taken, the AIMI-processed MgB2 wires will exhibit incomplete MgB2 layer formation, i.e. reduced superconductor core size and hence suppressed current-carrying capability. Microstructural characterization of AIMI MgB2 wires before and after the heat treatment reveals that the reaction mechanism changes from a “Mg infiltration-reaction” at the beginning of the heat treatment to a “Mg diffusion-reaction” once a dense MgB2 layer is formed. A drastic drop in the Mg transport rate from infiltration to diffusion causes the termination of the MgB2 core growth. To quantify this process, a two-stage kinetic model is built to describe the MgB2 layer formation and growth. The derived kinetic model and the associated experimental observations indicate that fully reacted AIMI-processed MgB2 wires can be achieved following the optimization of B particle size, B powder packing density, MgB2 reaction activation energy and its response to the additions of dopants. PMID:26973431

i3b3: Infobuttons for i2b2 as a Mechanism for Investigating the Information Needs of Clinical Researchers.

PubMed

Kennell, Timothy; Dempsey, Donald M; Cimino, James J

2016-01-01

The information needs of clinicians, as they interact with the EHR, are well-studied. Clinical researchers also interact with the EHR and, while they might be expected to have some similar needs, the unique needs that arise due to nature of their work remain largely unstudied. For clinicians, infobuttons (context-aware hyperlinks) provide a mechanism of studying these information needs. Here we describe the integration of infobuttons into i2b2, a popular data warehouse commonly used by clinical researchers, using a plugin. A preliminary survey of i2b2 developers suggests a general interest in infobuttons for i2b2 and indicates good likelihood for their deployment, where they may be used as a tool for further studying these needs in greater detail.

Oxidation of ZrB2-and HfB2-Based Ultra-High Temperature Ceramics: Effects of Ta Additions

NASA Technical Reports Server (NTRS)

Opila, Elizabeth; Levine, Stanley; Lorinez, Jonathan

2003-01-01

Several compositions of ZrB2- and HfB2-based Ultra-High Temperature Ceramics (UHTC) were oxidized in stagnant air at 1627 C in ten minute cycles for times up to 100 minutes. These compositions include: ZrB2 - 20v% SiC, HfB2 - 20v% SiC, ZrB2 - 20v% SiC - 20v% TaSi2, ZrB2 - 33v% SiC, HfB2 - 20v% SiC - 20v% TaSi2, and ZrB2 - 20v% SiC - 20v% TaC. The weight change due to oxidation was recorded. The ZrB2 - 20v% SiC - 20v% TaSi2 composition was also oxidized in stagnant air at 1927 C and in an arc jet atmosphere. Samples were analyzed after oxidation by x-ray diffraction, field emission scanning electron microscopy, and energy dispersive spectroscopy to determine the reaction products and to observe the microstructure. The ZrB2 - 20v% SiC - 20v% TaSi2 showed the lowest oxidation rate at 1627 C, but performed poorly under the more extreme tests due to liquid phase formation. Effects of Ta-additions on the oxidation of the diboride-based UHTC are discussed.

Separate Fe-S Scaffold And Carrier Functions For SufB2C2 And SufA During In Vitro Maturation Of [2Fe-2S] Fdx

PubMed Central

Chahal, Harsimranjit K.; Outten, F. Wayne

2012-01-01

Iron-sulfur (Fe-S) clusters are inorganic cofactors required for a variety of biological processes. In vivo biogenesis of Fe-S clusters proceeds via complex pathways involving multiple protein complexes. In the Suf Fe-S cluster biogenesis system, SufB may be a scaffold for nascent Fe-S cluster assembly whereas SufA is proposed to act as either a scaffold or an Fe-S cluster carrier from the scaffold to target apo-proteins. However, SufB can form multiple stable complexes with other Suf proteins, such as SufB2C2 and SufBC2D and the specific functions of these complexes in Fe-S cluster assembly are not clear. Here we compare the ability of the SufB2C2 and SufBC2D complexes as well as SufA to promote in vitro maturation of the [2Fe-2S] ferredoxin (Fdx). We found that SufB2C2 was most proficient as a scaffold for de novo assembly of holo-Fdx using sulfide and iron as freely available building blocks while SufA was best at direct transfer of a pre-formed Fe-S cluster to Fdx. Furthermore, cluster transfer from [4Fe-4S] SufB2C2 or SufBC2D to Fdx will proceed through a SufA intermediate to Fdx is SufA is present. Finally, addition of ATP repressed cluster transfer from [4Fe-4S] SufB2C2 to Fdx and from SufBC2D to [2Fe-2S] SufA or Fdx. These studies indicate that SufB2C2 can serve as a terminal scaffold to load the SufA Fe-S cluster carrier for in vitro maturation of [2Fe-2S] enzymes like Fdx. This work is the first to systematically compare the cluster transfer rates of a scaffold (SufB) to the transfer rates of a carrier (SufA) under the same conditions to the same target enzyme and is also the first to reconstitute the full transfer pathway (from scaffold to carrier to target enzyme) in a single reaction. PMID:23018275

Structural and functional characterizations of activin type 2B receptor (acvr2b) ortholog from the marine fish, gilthead sea bream, Sparus aurata: evidence for gene duplication of acvr2b in fish.

PubMed

Funkenstein, Bruria; Krol, Ekaterina; Esterin, Elena; Kim, Yong-Soo

2012-12-01

Myostatin (MSTN), a negative regulator of muscle growth and a member of the transforming growth factor-β superfamily, can bind the two activin type 2 receptors (ACVR2). It has been previously shown that WT mice injected with ACVR2B extracellular domain (ACVR2B-ECD) had higher muscle mass. Likewise, fish larvae immersed in Pichia pastoris culture supernatant, containing goldfish Acvr2b-ECD, showed enhanced larval growth. However, it is not clear whether fish Mstn1 and Mstn2 signal through the same receptor and whether fish express more than one acvr2b gene. In the current study, three cDNAs encoding acvr2b (saacvr2b-1, saacvr2b-2a, and saacvr2b-2b) were cloned from gilthead sea bream. All three contain the short extracellular binding domain, a short transmembrane region, and a conserved catalytic domain of serine/threonine protein kinase. Bioinformatics analysis provided evidence for the existence of two acvr2b genes (acvr2b-1 and acvr2b-2) in several other fish species as well, probably as a result of gene or genome duplication. The two isoforms differ in their amino acid sequences. The direct inhibitory effect of Acvr2b-ECD on Mstn activity was tested in vitro. The saAcvr2b-1-ECD was expressed in the yeast P. pastoris. Evidence is provided for N-glycosylation of Acvr2b-1-ECD. The affinity-purified Acvr2b-1-ECD inhibited recombinant mouse/rat/human mature MSTN activity when determined in vitro using the CAGA-luciferase assay in A204 cells. A lower inhibitory activity was obtained when unprocessed purified, furin-digested, and activated saMstn1 was used. Results of this study demonstrate for the first time the existence of two acvr2b genes in fish. In addition, the study shows that bioactive fish Acvr2b-ECD can be produced from P. pastoris.

Interactions between Cytochromes P450 2B4 (CYP2B4) and 1A2 (CYP1A2) Lead to Alterations in Toluene Disposition and P450 Uncoupling

PubMed Central

Reed, James R.; Cawley, George F.; Backes, Wayne L.

2013-01-01

The goal of this study was to characterize the effects of CYP1A2•CYP2B4 complex formation on the rates and efficiency of toluene metabolism by comparing the results from simple reconstituted systems containing P450 reductase (CPR) and a single P450 to those using a mixed system containing CPR and both P450s. In the mixed system, the rates of formation of CYP2B4-specific benzyl alcohol and p-cresol were inhibited, whereas that of CYP1A2-specific o-cresol was increased, results consistent with the formation of a CYP1A2•CYP2B4 complex where the CYP1A2 moiety has higher affinity for CPR binding. Comparison of the rates of NADPH oxidation and production of hydrogen peroxide and excess water by the simple and mixed systems indicated that excess water formed at a much lower rate in the mixed system. The commensurate increase in the rate of CYP1A2-specific product formation suggested the P450•P450 interaction increased the putative rate-limiting step of CYP1A2 catalysis, abstraction of a hydrogen radical from the substrate. Cumene hydroperoxide-supported metabolism was measured to determine whether the effects of the P450•P450 interaction required the presence of CPR. Peroxidative metabolism was not affected by the interaction of the two P450s, even with CPR present. However, CPR did stimulate peroxidative metabolism by the simple system containing CYP1A2. These results suggest the major functional effects of the P450•P450 interaction are mediated by changes in the relative abilities of the P450s to receive electrons from CPR. Furthermore, CPR may play an effector role by causing a conformation change in CYP1A2 that makes its metabolism more efficient. PMID:23675771