Sample records for tackle sizeable problems

  1. Using Invention to Change How Students Tackle Problems

    PubMed Central

    Smith, Karen M.; van Stolk, Adrian P.; Spiegelman, George B.

    2010-01-01

    Invention activities challenge students to tackle problems that superficially appear unrelated to the course material but illustrate underlying fundamental concepts that are fundamental to material that will be presented. During our invention activities in a first-year biology class, students were presented with problems that are parallel to those that living cells must solve, in weekly sessions over a 13-wk term. We compared students who participated in the invention activities sessions with students who participated in sessions of structured problem solving and with students who did not participate in either activity. When faced with developing a solution to a challenging and unfamiliar biology problem, invention activity students were much quicker to engage with the problem and routinely provided multiple reasonable hypotheses. In contrast the other students were significantly slower in beginning to work on the problem and routinely produced relatively few ideas. We suggest that the invention activities develop a highly valuable skill that operates at the initial stages of problem solving. PMID:21123697

  2. Management of sizeable carotid body tumor: Case report and review of literature.

    PubMed

    Elsharawy, Mohamed A; Alsaif, Hind; Elsaid, Aymen; Kredees, Ali

    2013-10-01

    Carotid body tumor is a paraganglioma derived from the neural crest. It arises from the carotid body which acts as a vascular chemoreceptors and is usually located at the carotid bifurcation. Sizeable (Shamblin III, >5 cm size) tumors are large and typically encase the carotid artery requiring vessel resection and replacement. Management of such tumors carries a high risk of postoperative mortality and morbidity rates specially with regards to neurovascular complications. We report a case of sizeable tumor which was surgically removed with minimal complications.

  3. Management of sizeable carotid body tumor: Case report and review of literature

    PubMed Central

    Elsharawy, Mohamed A; Alsaif, Hind; Elsaid, Aymen; Kredees, Ali

    2013-01-01

    Carotid body tumor is a paraganglioma derived from the neural crest. It arises from the carotid body which acts as a vascular chemoreceptors and is usually located at the carotid bifurcation. Sizeable (Shamblin III, >5 cm size) tumors are large and typically encase the carotid artery requiring vessel resection and replacement. Management of such tumors carries a high risk of postoperative mortality and morbidity rates specially with regards to neurovascular complications. We report a case of sizeable tumor which was surgically removed with minimal complications. PMID:24327970

  4. Tackling wicked problems in infection prevention and control: a guideline for co-creation with stakeholders.

    PubMed

    van Woezik, Anne F G; Braakman-Jansen, Louise M A; Kulyk, Olga; Siemons, Liseth; van Gemert-Pijnen, Julia E W C

    2016-01-01

    Infection prevention and control can be seen as a wicked public health problem as there is no consensus regarding problem definition and solution, multiple stakeholders with different needs and values are involved, and there is no clear end-point of the problem-solving process. Co-creation with stakeholders has been proposed as a suitable strategy to tackle wicked problems, yet little information and no clear step-by-step guide exist on how to do this. The objectives of this study were to develop a guideline to assist developers in tackling wicked problems using co-creation with stakeholders, and to apply this guideline to practice with an example case in the field of infection prevention and control. A mixed-method approach consisting of the integration of both quantitative and qualitative research was used. Relevant stakeholders from the veterinary, human health, and public health sectors were identified using a literature scan, expert recommendations, and snowball sampling. The stakeholder salience approach was used to select key stakeholders based on 3 attributes: power, legitimacy, and urgency. Key values of stakeholders (N = 20) were derived by qualitative semi-structured interviews and quantitatively weighted and prioritized using an online survey. Our method showed that stakeholder identification and analysis are prerequisites for understanding the complex stakeholder network that characterizes wicked problems. A total of 73 stakeholders were identified of which 36 were selected as potential key stakeholders, and only one was seen as a definite stakeholder. In addition, deriving key stakeholder values is a necessity to gain insights into different problem definitions, solutions and needs stakeholders have regarding the wicked problem. Based on the methods used, we developed a step-by-step guideline for co-creation with stakeholders when tackling wicked problems. The mixed-methods guideline presented here provides a systematic, transparent method to

  5. Cognition of an expert tackling an unfamiliar conceptual physics problem

    NASA Astrophysics Data System (ADS)

    Schuster, David; Undreiu, Adriana

    2009-11-01

    We have investigated and analyzed the cognition of an expert tackling a qualitative conceptual physics problem of an unfamiliar type. Our goal was to elucidate the detailed cognitive processes and knowledge elements involved, irrespective of final solution form, and consider implications for instruction. The basic but non-trivial problem was to find qualitatively the direction of acceleration of a pendulum bob at various stages of its motion, a problem originally studied by Reif and Allen. Methodology included interviews, introspection, retrospection and self-reported metacognition. Multiple facets of cognition were revealed, with different reasoning strategies used at different stages and for different points on the path. An account is given of the zigzag thinking paths and interplay of reasoning modes and schema elements involved. We interpret the cognitive processes in terms of theoretical concepts that emerged, namely: case-based, principle-based, experiential-intuitive and practical-heuristic reasoning; knowledge elements and schemata; activation; metacognition and epistemic framing. The complexity of cognition revealed in this case study contrasts with the tidy principle-based solutions we present to students. The pervasive role of schemata, case-based reasoning, practical heuristic strategies, and their interplay with physics principles is noteworthy, since these aspects of cognition are generally neither recognized nor taught. The schema/reasoning-mode perspective has direct application in science teaching, learning and problem-solving.

  6. Link-prediction to tackle the boundary specification problem in social network surveys

    PubMed Central

    De Wilde, Philippe; Buarque de Lima-Neto, Fernando

    2017-01-01

    Diffusion processes in social networks often cause the emergence of global phenomena from individual behavior within a society. The study of those global phenomena and the simulation of those diffusion processes frequently require a good model of the global network. However, survey data and data from online sources are often restricted to single social groups or features, such as age groups, single schools, companies, or interest groups. Hence, a modeling approach is required that extrapolates the locally restricted data to a global network model. We tackle this Missing Data Problem using Link-Prediction techniques from social network research, network generation techniques from the area of Social Simulation, as well as a combination of both. We found that techniques employing less information may be more adequate to solve this problem, especially when data granularity is an issue. We validated the network models created with our techniques on a number of real-world networks, investigating degree distributions as well as the likelihood of links given the geographical distance between two nodes. PMID:28426826

  7. The persistent problem of lead poisoning in birds from ammunition and fishing tackle

    USGS Publications Warehouse

    Haig, Susan M.; D'Elia, Jesse; Eagles-Smith, Collin A.; Fair, Jeanne M.; Gervais, Jennifer; Herring, Garth; Rivers, James W.; Schulz, John H.

    2014-01-01

    Lead (Pb) is a metabolic poison that can negatively influence biological processes, leading to illness and mortality across a large spectrum of North American avifauna (>120 species) and other organisms. Pb poisoning can result from numerous sources, including ingestion of bullet fragments and shot pellets left in animal carcasses, spent ammunition left in the field, lost fishing tackle, Pb-based paints, large-scale mining, and Pb smelting activities. Although Pb shot has been banned for waterfowl hunting in the United States (since 1991) and Canada (since 1999), Pb exposure remains a problem for many avian species. Despite a large body of scientific literature on exposure to Pb and its toxicological effects on birds, controversy still exists regarding its impacts at a population level. We explore these issues and highlight areas in need of investigation: (1) variation in sensitivity to Pb exposure among bird species; (2) spatial extent and sources of Pb contamination in habitats in relation to bird exposure in those same locations; and (3) interactions between avian Pb exposure and other landscape-level stressors that synergistically affect bird demography. We explore multiple paths taken to reduce Pb exposure in birds that (1) recognize common ground among a range of affected interests; (2) have been applied at local to national scales; and (3) engage governmental agencies, interest groups, and professional societies to communicate the impacts of Pb ammunition and fishing tackle, and to describe approaches for reducing their availability to birds. As they have in previous times, users of fish and wildlife will play a key role in resolving the Pb poisoning issue.

  8. A Legal Approach to Tackling Contract Cheating?

    ERIC Educational Resources Information Center

    Draper, Michael J.; Newton, Philip M.

    2017-01-01

    The phenomenon of contract cheating presents, potentially, a serious threat to the quality and standards of Higher Education around the world. There have been suggestions, cited below, to tackle the problem using legal means, but we find that current laws are not fit for this purpose. In this article we present a proposal for a specific new law to…

  9. Tackling a Local Problem.

    ERIC Educational Resources Information Center

    Cook, Martin

    1995-01-01

    Students studying water as a class project were concerned by levels of pollution at a nearby river and the local beach. They identified three environmental problems for research including sewage discharge, beach litter, and quality of swimming water. Research consisted of field trips which allowed for opportunities to improve skills in collecting…

  10. Tackling antibiotic resistance in India.

    PubMed

    Wattal, Chand; Goel, Neeraj

    2014-12-01

    Infectious diseases are major causes of mortality in India. This is aggravated by the increasing prevalence of antimicrobial resistance (AMR) both in the community and in hospitals. Due to the emergence of resistance to all effective antibiotics in nosocomial pathogens, the situation calls for emergency measures to tackle AMR in India. India has huge challenges in tackling AMR, ranging from lack of surveillance mechanisms for monitoring AMR and use; effective hospital control policies; sanitation and non-human use of antimicrobial. The Ministry of Health and Family Welfare of Govt. of India has taken initiatives to tackle AMR. Extensive guidelines have been drafted and a model worksheet has been developed as a roadmap to tackle AMR.

  11. Factors influencing tackle injuries in rugby union football

    PubMed Central

    Garraway, W. M.; Lee, A. J.; Macleod, D. A.; Telfer, J. W.; Deary, I. J.; Murray, G. D.

    1999-01-01

    OBJECTIVES: To assess the influence of selected aspects of lifestyle, personality, and other player related factors on injuries in the tackle. To describe the detailed circumstances in which these tackles occurred. METHODS: A prospective case-control study was undertaken in which the tackling and tackled players ("the cases") involved in a tackle injury were each matched with "control" players who held the same respective playing positions in the opposing teams. A total of 964 rugby matches involving 71 senior clubs drawn from all districts of the Scottish Rugby Union (SRU) were observed by nominated linkmen who administered self report questionnaires to the players identified as cases and controls. Information on lifestyle habits, match preparation, training, and coaching experience was obtained. A validated battery of psychological tests assessed players' trait anger and responses to anger and hostility. The circumstances of the tackles in which injury occurred were recorded by experienced SRU coaching staff in interviews with involved players after the match. RESULTS: A total of 71 tackle injury episodes with correct matching of cases and controls were studied. The following player related factors did not contribute significantly to tackle injuries: alcohol consumption before the match, feeling "below par" through minor illness, the extent of match preparation, previous coaching, or practising tackling. Injured and non- injured players in the tackle did not differ in their disposition toward, or expression of, anger or hostility. Some 85% of tackling players who were injured were three quarters, and 52% of injuries occurred when the tackle came in behind the tackled player or within his peripheral vision. Either the tackling or tackled player was sprinting or running in all of these injury episodes. One third of injuries occurred in differential speed tackles--that is, when one player was travelling much faster than the other at impact. The player with the lower

  12. Tackling in Youth Football.

    PubMed

    2015-11-01

    American football remains one of the most popular sports for young athletes. The injuries sustained during football, especially those to the head and neck, have been a topic of intense interest recently in both the public media and medical literature. The recognition of these injuries and the potential for long-term sequelae have led some physicians to call for a reduction in the number of contact practices, a postponement of tackling until a certain age, and even a ban on high school football. This statement reviews the literature regarding injuries in football, particularly those of the head and neck, the relationship between tackling and football-related injuries, and the potential effects of limiting or delaying tackling on injury risk. Copyright © 2015 by the American Academy of Pediatrics.

  13. Tackling Work Related Stress in a National Health Service Trust

    ERIC Educational Resources Information Center

    Vick, Donna; Whyatt, Hilary

    2004-01-01

    The challenge of tackling the problem of coping with work related stress in a National Health Service (NHS) Trust was undertaken. Ideas were developed within the context of two different action learning sets and led to actions resulting in a large therapy Taster Session event and the establishment of a centre offering alternative therapies and…

  14. Tackle technique and tackle-related injuries in high-level South African Rugby Union under-18 players: real-match video analysis.

    PubMed

    Burger, Nicholas; Lambert, Michael I; Viljoen, Wayne; Brown, James C; Readhead, Clint; Hendricks, Sharief

    2016-08-01

    The high injury rate associated with rugby union is primarily due to the tackle, and poor contact technique has been identified as a risk factor for injury. We aimed to determine whether the tackle technique proficiency scores were different in injurious tackles versus tackles that did not result in injury using real-match scenarios in high-level youth rugby union. Injury surveillance was conducted at the under-18 Craven Week tournaments (2011-2013). Tackle-related injury information was used to identify injury events in the match video footage and non-injury events were identified for the injured player cohort. Injury and non-injury events were scored for technique proficiency and Cohen's effect sizes were calculated and the Student t test (p<0.05) was performed to compare injury versus non-injury scores. The overall mean score for front-on ball-carrier proficiency was 7.17±1.90 and 9.02±2.15 for injury and non-injury tackle events, respectively (effect size=moderate; p<0.05). The overall mean score for side/behind ball-carrier proficiency was 4.09±2.12 and 7.68±1.72 for injury and non-injury tackle events, respectively (effect size=large; p<0.01). The overall mean score for front-on tackler proficiency was 7.00±1.95 and 9.35±2.56 for injury and non-injury tackle events, respectively (effect size=moderate; p<0.05). The overall mean score for side/behind tackler proficiency was 5.47±1.60 and 8.14±1.75 for injury and non-injury tackle events, respectively (effect size=large; p<0.01). Higher overall mean and criterion-specific tackle-related technique scores were associated with a non-injury outcome. The ability to perform well during tackle events may decrease the risk of injury and may manifest in superior performance. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  15. The Role of Labour Inspectorates in Tackling the Psychosocial Risks at Work in Europe: Problems and Perspectives

    PubMed Central

    Toukas, Dimitrios; Delichas, Miltiadis; Toufekoula, Chryssoula; Spyrouli, Anastasia

    2015-01-01

    Significant changes in the past year have taken place in the world of work that are bringing new challenges with regard to employee safety and health. These changes have led to emerging psychosocial risks (PSRs) at work. The risks are primarily linked to how work is designed, organized, and managed, and to the economic and social frame of work. These factors have increased the level of work-related stress and can lead to serious deterioration in mental and physical health. In tackling PSRs, the European labor inspectorates can have an important role by enforcing preventive and/or corrective interventions in the content and context of work. However, to improve working conditions, unilateral interventions in the context and content of work are insufficient and require adopting a common strategy to tackle PSRs, based on a holistic approach. The implementation of a common strategy by the European Labor Inspectorate for tackling PSRs is restricted by the lack of a common legislative frame with regard to PSR evaluation and management, the different levels of labor inspectors' training, and the different levels of employees' and employers' health and safety culture. PMID:26929837

  16. 46 CFR 184.300 - Ground tackle and mooring lines.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Ground tackle and mooring lines. 184.300 Section 184.300... Ground tackle and mooring lines. A vessel must be fitted with ground tackle and mooring lines necessary for the vessel to be safely anchored or moored. The ground tackle and mooring lines provided must be...

  17. 46 CFR 184.300 - Ground tackle and mooring lines.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Ground tackle and mooring lines. 184.300 Section 184.300... Ground tackle and mooring lines. A vessel must be fitted with ground tackle and mooring lines necessary for the vessel to be safely anchored or moored. The ground tackle and mooring lines provided must be...

  18. Tackle mechanisms and match characteristics in women's elite football tournaments.

    PubMed

    Tscholl, P; O'Riordan, D; Fuller, C W; Dvorak, J; Junge, A

    2007-08-01

    Several tools have been used for assessing risk situations and for gathering tackle information from international football matches for men but not for women. To analyse activities in women's football and to identify the characteristics and risk potentials of tackles. Retrospective video analysis. Video recordings of 24 representative matches from six women's top-level tournaments were analysed for tackle parameters and their risk potential. 3531 tackles were recorded. Tackles in which the tackling player came from the side and stayed on her feet accounted for nearly half of all challenges for the ball in which body contact occurred. 2.7% of all tackles were classified as risk situations, with sliding-in tackles from behind and the side having the highest risk potential. Match referees sanctioned sliding-in tackles more often than other tackles (20% v 17%, respectively). Tackle parameters did not change in the duration of a match; however, there was an increase in the number of injury risk situations and foul plays towards the end of each half. Match properties provide valuable information for a better understanding of injury situations in football. Staying on feet and jumping vertically tackle actions leading to injury were sanctioned significantly more times by the referee than those not leading to injury (p<0.001), but no such difference was seen for sliding-in tackles (previously reported to have the highest injury potential in women's football). Therefore, either the laws of the game are not adequate or match referees in women's football are not able to distinguish between sliding-in tackles leading to and those not leading to injury.

  19. Non-sanctioning of illegal tackles in South African youth community rugby.

    PubMed

    Brown, J C; Boucher, S J; Lambert, M; Viljoen, W; Readhead, C; Hendricks, S; Kraak, W J

    2018-06-01

    The tackle event in rugby union ('rugby') contributes to the majority of players' injuries. Referees can reduce this risk by sanctioning dangerous tackles. A study in elite adult rugby suggests that referees only sanction a minority of illegal tackles. The aim of this study was to assess if this finding was similar in youth community rugby. Observational study. Using EncodePro, 99 South African Rugby Union U18 Youth Week tournament matches were coded between 2011 and 2015. All tackles were coded by a researcher and an international referee to ensure that laws were interpreted correctly. The inter- and intra-rater reliabilities were 0.97-1.00. A regression analysis compared the non-sanctioned rates over time. In total, 12 216 tackles were coded, of which less than 1% (n=113) were 'illegal'. The majority of the 113 illegal tackles were front-on (75%), high tackles (72%) and occurred in the 2nd/4th quarters (29% each). Of the illegal tackles, only 59% were sanctioned. The proportions of illegal tackles and sanctioning of these illegal tackles to all tackles improved by 0.2% per year from 2011-2015 (p<0.05). In these youth community rugby players, 59% of illegal tackles were not sanctioned appropriately. This was better than a previous study in elite adult rugby, where only 7% of illegal tackles were penalised. Moreover, the rates of illegal tackles and non-sanctioned illegal tackles both improved over time. However, it is critical that referees consistently enforce all laws to enhance injury prevention efforts. Further studies should investigate the reasons for non-sanctioning. Copyright © 2017 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  20. Wind Turbine Failures - Tackling current Problems in Failure Data Analysis

    NASA Astrophysics Data System (ADS)

    Reder, M. D.; Gonzalez, E.; Melero, J. J.

    2016-09-01

    The wind industry has been growing significantly over the past decades, resulting in a remarkable increase in installed wind power capacity. Turbine technologies are rapidly evolving in terms of complexity and size, and there is an urgent need for cost effective operation and maintenance (O&M) strategies. Especially unplanned downtime represents one of the main cost drivers of a modern wind farm. Here, reliability and failure prediction models can enable operators to apply preventive O&M strategies rather than corrective actions. In order to develop these models, the failure rates and downtimes of wind turbine (WT) components have to be understood profoundly. This paper is focused on tackling three of the main issues related to WT failure analyses. These are, the non-uniform data treatment, the scarcity of available failure analyses, and the lack of investigation on alternative data sources. For this, a modernised form of an existing WT taxonomy is introduced. Additionally, an extensive analysis of historical failure and downtime data of more than 4300 turbines is presented. Finally, the possibilities to encounter the lack of available failure data by complementing historical databases with Supervisory Control and Data Acquisition (SCADA) alarms are evaluated.

  1. 46 CFR 121.300 - Ground tackle and mooring lines.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Ground tackle and mooring lines. 121.300 Section 121.300... MISCELLANEOUS SYSTEMS AND EQUIPMENT Mooring and Towing Equipment § 121.300 Ground tackle and mooring lines. A vessel must be fitted with ground tackle and mooring lines necessary for the vessel to be safely anchored...

  2. 46 CFR 121.300 - Ground tackle and mooring lines.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Ground tackle and mooring lines. 121.300 Section 121.300... MISCELLANEOUS SYSTEMS AND EQUIPMENT Mooring and Towing Equipment § 121.300 Ground tackle and mooring lines. A vessel must be fitted with ground tackle and mooring lines necessary for the vessel to be safely anchored...

  3. Tackle and impact detection in elite Australian football using wearable microsensor technology.

    PubMed

    Gastin, Paul B; McLean, Owen C; Breed, Ray V P; Spittle, Michael

    2014-01-01

    The effectiveness of a wearable microsensor device (MinimaxX(TM) S4, Catapult Innovations, Melbourne, VIC, Australia) to automatically detect tackles and impact events in elite Australian football (AF) was assessed during four matches. Video observation was used as the criterion measure. A total of 352 tackles were observed, with 78% correctly detected as tackles by the manufacturer's software. Tackles against (i.e. tackled by an opponent) were more accurately detected than tackles made (90% v 66%). Of the 77 tackles that were not detected at all, the majority (74%) were categorised as low-intensity. In contrast, a total of 1510 "tackle" events were detected, with only 18% of these verified as tackles. A further 57% were from contested ball situations involving player contact. The remaining 25% were in general play where no contact was evident; these were significantly lower in peak Player Load™ than those involving player contact (P < 0.01). The tackle detection algorithm, developed primarily for rugby, was not suitable for tackle detection in AF. The underlying sensor data may have the potential to detect a range of events within contact sports such as AF, yet to do so is a complex task and requires sophisticated sport and event-specific algorithms.

  4. Tenderfooting: Tackling the Problems of Freshman Writers.

    ERIC Educational Resources Information Center

    Hobbs, Valerie; Rex-Kerish, Lesley

    1986-01-01

    University of California writing instructors must teach poorly prepared freshmen how to survive English classes and how to adapt the skills they learn to the rest of their university writing assignments. Reading, thinking, organizing, and stylistic problems are discussed. (MLW)

  5. Momentum and Kinetic Energy Before the Tackle in Rugby Union

    PubMed Central

    Hendricks, Sharief; Karpul, David; Lambert, Mike

    2014-01-01

    Understanding the physical demands of a tackle in match situations is important for safe and effective training, developing equipment and research. Physical components such as momentum and kinetic energy, and it relationship to tackle outcome is not known. The aim of this study was to compare momenta between ball-carrier and tackler, level of play (elite, university and junior) and position (forwards vs. backs), and describe the relationship between ball-carrier and tackler mass, velocity and momentum and the tackle outcome. Also, report on the ball-carrier and tackler kinetic energy before contact and the estimated magnitude of impact (energy distributed between ball-carrier and tackler upon contact). Velocity over 0.5 seconds before contact was determined using a 2-dimensional scaled version of the field generated from a computer alogorithm. Body masses of players were obtained from their player profiles. Momentum and kinetic energy were subsequently calculated for 60 tackle events. Ball-carriers were heavier than the tacklers (ball-carrier 100 ± 14 kg vs. tackler 93 ± 11 kg, d = 0.52, p = 0.0041, n = 60). Ball-carriers as forwards had a significantly higher momentum than backs (forwards 563 ± 226 Kg.m.s-1 n = 31 vs. backs 438 ± 135 Kg.m.s-1, d = 0.63, p = 0.0012, n = 29). Tacklers dominated 57% of tackles and ball-carriers dominated 43% of tackles. Despite the ball-carrier having a mass advantage before contact more frequently than the tackler, momentum advantage and tackle dominance between the ball-carrier and tackler was proportionally similar. These findings may reflect a characteristic of the modern game of rugby where efficiently heavier players (particularly forwards) are tactically predetermined to carry the ball in contact. Key Points First study to quantify momentum, kinetic energy, and magnitude of impact in rugby tackles across different levels in matches without a device attached to a player. Physical components alone, of either ball-carrier or

  6. Momentum and kinetic energy before the tackle in rugby union.

    PubMed

    Hendricks, Sharief; Karpul, David; Lambert, Mike

    2014-09-01

    Understanding the physical demands of a tackle in match situations is important for safe and effective training, developing equipment and research. Physical components such as momentum and kinetic energy, and it relationship to tackle outcome is not known. The aim of this study was to compare momenta between ball-carrier and tackler, level of play (elite, university and junior) and position (forwards vs. backs), and describe the relationship between ball-carrier and tackler mass, velocity and momentum and the tackle outcome. Also, report on the ball-carrier and tackler kinetic energy before contact and the estimated magnitude of impact (energy distributed between ball-carrier and tackler upon contact). Velocity over 0.5 seconds before contact was determined using a 2-dimensional scaled version of the field generated from a computer alogorithm. Body masses of players were obtained from their player profiles. Momentum and kinetic energy were subsequently calculated for 60 tackle events. Ball-carriers were heavier than the tacklers (ball-carrier 100 ± 14 kg vs. tackler 93 ± 11 kg, d = 0.52, p = 0.0041, n = 60). Ball-carriers as forwards had a significantly higher momentum than backs (forwards 563 ± 226 Kg(.)m(.)s(-1) n = 31 vs. backs 438 ± 135 Kg(.)m(.)s(-1), d = 0.63, p = 0.0012, n = 29). Tacklers dominated 57% of tackles and ball-carriers dominated 43% of tackles. Despite the ball-carrier having a mass advantage before contact more frequently than the tackler, momentum advantage and tackle dominance between the ball-carrier and tackler was proportionally similar. These findings may reflect a characteristic of the modern game of rugby where efficiently heavier players (particularly forwards) are tactically predetermined to carry the ball in contact. Key PointsFirst study to quantify momentum, kinetic energy, and magnitude of impact in rugby tackles across different levels in matches without a device attached to a player.Physical components alone, of either ball

  7. Tackle characteristics and injury in a cross section of rugby union football.

    PubMed

    McIntosh, Andrew S; Savage, Trevor N; McCrory, Paul; Fréchède, Bertrand O; Wolfe, Rory

    2010-05-01

    The tackle is the game event in rugby union most associated with injury. This study's main aims were to measure tackle characteristics from video using a qualitative protocol, to assess whether the characteristics differed by level of play, and to measure the associations between tackle characteristics and injury. A cohort study was undertaken. The cohort comprised male rugby players in the following levels: younger than 15 yr, 18 yr, and 20 yr, grade, and elite (Super 12 and Wallabies). All tackle events and technique characteristics were coded in 77 game halves using a standardized qualitative protocol. Game injuries and missed-game injuries were identified and correlated with tackle events. A total of 6618 tackle events, including 81 resulting in a game injury, were observed and coded in the 77 game halves fully analyzed (145 tackle events per hour). An increase in the proportion of active shoulder tackles was observed from younger than 15 yr (13%) to elite (31%). Younger players engaged in more passive tackles and tended to stay on their feet more than experienced players. Younger than 15 yr rugby players had a significantly lower risk of tackle game injury compared with elite players. No specific tackle technique was observed to be associated with a significantly increased risk of game injury. There was a greater risk of game injury associated with two or more tacklers involved in the tackle event, and the greatest risk was associated with simultaneous contact by tacklers, after adjusting for level of play. Tackle characteristics differed between levels of play. The number of tacklers and the sequence of tackler contact with the ball carrier require consideration from an injury prevention perspective.

  8. Technical determinants of tackle and ruck performance in International rugby union.

    PubMed

    Hendricks, Sharief; van Niekerk, Tiffany; Sin, Drew Wade; Lambert, Mike; den Hollander, Steve; Brown, James; Maree, Willie; Treu, Paul; Till, Kevin; Jones, Ben

    2018-03-01

    The most frequently occurring contact events in rugby union are the tackle and ruck. The ability repeatedly to engage and win the tackle and ruck has been associated with team success. To win the tackle and ruck, players have to perform specific techniques. These techniques have not been studied at the highest level of rugby union. Therefore, the purpose of this study was to identify technical determinants of tackle and ruck performance at the highest level of rugby union. A total of 4479 tackle and 2914 ruck events were coded for the Six Nations and Championship competitions. Relative risk ratio (RR), the ratio of the probability of an outcome occurring when a characteristic was observed (versus the non-observed characteristic), was determined using multinomial logistic regression. Executing front-on tackles reduced the likelihood of offloads and tackle breaks in both competitions (Six Nations RR 3.0 Behind tackle, 95% confidence interval [95% CI]: 1.9-4.6, effect size [ES] = large, P < 0.001); Championship RR 2.9 Jersey tackle, 95% CI: 1.3-6.4, ES = moderate, P = 0.01). Fending during contact increased the chances of offloading and breaking the tackle in both competitions (Six Nations RR 4.5 Strong, 95% CI: 2.2-9.2, ES = large, P = P < 0.001; Championship RR 5.1 Moderate, 95% CI: 3.5-7.4, ES = large, P < 0.001). For the ruck, actively placing the ball increased the probability of maintaining possession (Six Nations RR 2.2, 95% CI: 1.1-4.3, ES = moderate, P = 0.03); Championship RR 4.0, 95% CI: 1.3-11.8, ES = large, P = 0.01). The techniques identified in this study should be incorporated and emphasised during training to prepare players for competition. Furthermore, these techniques need to be added to coaching manuals for the tackle and ruck.

  9. Beyond Individual Behaviour Change: The Role of Power, Knowledge and Strategy in Tackling Climate Change

    ERIC Educational Resources Information Center

    Kenis, Anneleen; Mathijs, Erik

    2012-01-01

    Individual behaviour change is fast becoming a kind of "holy grail" to tackle climate change, in environmental policy, the environmental movement and academic literature. This is contested by those who claim that social structures are the main problem and who advocate collective social action. The objective of the research presented in…

  10. Collapsed scrums and collision tackles: what is the injury risk?

    PubMed

    Roberts, Simon P; Trewartha, Grant; England, Mike; Stokes, Keith A

    2015-04-01

    To establish the propensity for specific contact events to cause injury in rugby union. Medical staff at participating English community-level rugby clubs reported any injury resulting in the absence for one match or more from the day of the injury during the 2009/2010 (n=46), 2010/2011 (n=67) and 2011/2012 (n=76) seasons. Injury severity was defined as the number of matches missed. Thirty community rugby matches were filmed and the number of contact events (tackles, collision tackles, rucks, mauls, lineouts and scrums) recorded. Of 370 (95% CI 364 to 378) contact events per match, 141 (137 to 145) were tackles, 115 (111 to 119) were rucks and 32 (30 to 33) were scrums. Tackles resulted in the greatest propensity for injury (2.3 (2.2 to 2.4) injuries/1000 events) and the greatest severity (16 (15 to 17) weeks missed/1000 events). Collision tackles (illegal tackles involving a shoulder charge) had a propensity for injury of 15 (12.4 to 18.3) injuries/1000 events and severity was 92 (75 to 112) weeks missed/1000 events, both of which were higher than any other event. Additional scrum analysis showed that only 5% of all scrums collapsed, but the propensity for injury was four times higher (2.9 (1.5 to 5.4) injuries/1000 events) and the severity was six times greater (22 (12 to 42) weeks missed/1000 events) than for non-collapsed scrums. Injury prevention in the tackle should focus on technique with strict enforcement of existing laws for illegal collision tackles. The scrum is a relatively controllable event and further attempts should be made to reduce the frequency of scrum collapse. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  11. Severe and Catastrophic Neck Injuries Resulting from Tackle Football

    ERIC Educational Resources Information Center

    Torg, Joseph S.; And Others

    1977-01-01

    Use of the spring-loaded blocking and tackling devices should be discontinued due to severe neck injuries resulting from their use; employment of the head and helmet as the primary assault weapon in blocking, tackling, and head butting should be condemned for the same reason. (MJB)

  12. 46 CFR 121.300 - Ground tackle and mooring lines.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Ground tackle and mooring lines. 121.300 Section 121.300 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS CARRYING MORE... MISCELLANEOUS SYSTEMS AND EQUIPMENT Mooring and Towing Equipment § 121.300 Ground tackle and mooring lines. A...

  13. An evaluation of sampling methods and supporting techniques for tackling lead in drinking water in Aberta Province

    EPA Science Inventory

    A collaborative project commenced in August 2013 with the aim of demonstrating a range of techniques that can be used in tackling the problems of lead in drinking water. The main project was completed in March 2014, with supplementary sampling exercises in mid-2014. It involved t...

  14. Tackling racism in the NHS.

    PubMed

    Dean, Erin

    2016-11-30

    Essential facts Trade union Unite has developed a policy briefing on a new toolkit to combat racism in the NHS. It can help nurses and other staff tackle racial discrimination in health, with black and minority ethnic (BME) nurses often treated unequally compared with their white colleagues.

  15. An investigation of shoulder forces in active shoulder tackles in rugby union football.

    PubMed

    Usman, Juliana; McIntosh, Andrew S; Fréchède, Bertrand

    2011-11-01

    In rugby union football the tackle is the most frequently executed skill and one most associated with injury, including shoulder injury to the tackler. Despite the importance of the tackle, little is known about the magnitude of shoulder forces in the tackle and influencing factors. The objectives of the study were to measure the shoulder force in the tackle, as well as the effects of shoulder padding, skill level, side of body, player size, and experimental setting on shoulder force. Experiments were conducted in laboratory and field settings using a repeated measures design. Thirty-five participants were recruited to the laboratory and 98 to the field setting. All were male aged over 18 years with rugby experience. The maximum force applied to the shoulder in an active shoulder tackle was measured with a custom built forceplate incorporated into a 45 kg tackle bag. The overall average maximum shoulder force was 1660 N in the laboratory and 1997 N in the field. This difference was significant. The shoulder force for tackling without shoulder pads was 1684 N compared to 1635 N with shoulder pads. There was no difference between the shoulder forces on the dominant and non-dominant sides. Shoulder force reduced with tackle repetition. No relationship was observed between player skill level and size. A substantial force can be applied to the shoulder and to an opponent in the tackle. This force is within the shoulder's injury tolerance range and is unaffected by shoulder pads. Copyright © 2011 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  16. Inquiry and Problem Solving.

    ERIC Educational Resources Information Center

    Thorson, Annette, Ed.

    1999-01-01

    This issue of ENC Focus focuses on the topic of inquiry and problem solving. Featured articles include: (1) "Inquiry in the Everyday World of Schools" (Ronald D. Anderson); (2) "In the Cascade Reservoir Restoration Project Students Tackle Real-World Problems" (Clint Kennedy with Advanced Biology Students from Cascade High…

  17. Tour of a Simple Trigonometry Problem

    ERIC Educational Resources Information Center

    Poon, Kin-Keung

    2012-01-01

    This article focuses on a simple trigonometric problem that generates a strange phenomenon when different methods are applied to tackling it. A series of problem-solving activities are discussed, so that students can be alerted that the precision of diagrams is important when solving geometric problems. In addition, the problem-solving plan was…

  18. Does player time-in-game affect tackle technique in elite level rugby union?

    PubMed

    Tierney, Gregory J; Denvir, Karl; Farrell, Garreth; Simms, Ciaran K

    2018-02-01

    It has been hypothesised that fatigue may be a major factor in tackle-related injury risk in rugby union and hence more injuries occur in the later stages of a game. The aim of this study is to identify changes in ball carrier or tackler proficiency characteristics, using elite level match video data, as player time-in-game increases. Qualitative observational cohort study. Three 2014/15 European Rugby Champions Cup games were selected for ball carrier and tackler proficiency analysis. Analysis was only conducted on players who started and remained on the field for the entire game. A separate analysis was conducted on 10 randomly selected 2014/15 European Rugby Champions Cup/Pro 12 games to assess the time distribution of tackles throughout a game. A Chi-square test and one-way way ANOVA with post-hoc testing was conducted to identify significant differences (p<0.05) for proficiency characteristics and tackle counts between quarters in the game, respectively. Player time-in-game did not affect tackle proficiency for both the ball carrier and tackler. Any results that showed statistical significance did not indicate a trend of deterioration in proficiency with increased player time-in-game. The time distribution of tackles analysis indicated that more tackles occurring in the final quarter of the game than the first (p=0.04) and second (p=<0.01). It appears that player time-in-game does not affect tackler or ball carrier tackle technique proficiency at the elite level. More tackles occurring in the final quarter of a game provides an alternative explanation to more tackle-related injuries occurring at this stage. Copyright © 2017 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  19. TSCA Section 21 Petition Requesting EPA to Regulate Lead in Fishing Tackle

    EPA Pesticide Factsheets

    This petition requests EPA to promulgate regulations under section 6 of TSCA to protect the environment from fishing tackle containing lead including fishing weights, sinkers, lures, jigs, and/or other tackle.

  20. Some Little Night Problems.

    ERIC Educational Resources Information Center

    Cannon, Lawrence O.; Elich, Joe

    In most mathematics problem solving work, students' motivation comes from trying to please their teachers or to earn a good grade. The questions students must tackle are almost never generated by their own interest. Seven open-ended college algebra-level problems are presented in which the solution of one question suggests other related questions.…

  1. The Paradox of Public Service Jefferson, Education, and the Problem of Plato's Cave

    ERIC Educational Resources Information Center

    Holowchak, M. Andrew

    2013-01-01

    Plato noticed a sizeable problem apropos of establishing his republic--that there was always a ready pool of zealous potential rulers, lying in wait for a suitable opportunity to rule on their own tyrannical terms. He also recognized that those persons best suited to rule, those persons with foursquare and unimpeachable virtue, would be least…

  2. Baltimore District Tackles High Suspension Rates

    ERIC Educational Resources Information Center

    Maxwell, Lesli A.

    2007-01-01

    This article reports on how the Baltimore District tackles its high suspension rates. Driven by an increasing belief that zero-tolerance disciplinary policies are ineffective, more educators are embracing strategies that do not exclude misbehaving students from school for offenses such as insubordination, disrespect, cutting class, tardiness, and…

  3. Adaptive Online Sequential ELM for Concept Drift Tackling

    PubMed Central

    Basaruddin, Chan

    2016-01-01

    A machine learning method needs to adapt to over time changes in the environment. Such changes are known as concept drift. In this paper, we propose concept drift tackling method as an enhancement of Online Sequential Extreme Learning Machine (OS-ELM) and Constructive Enhancement OS-ELM (CEOS-ELM) by adding adaptive capability for classification and regression problem. The scheme is named as adaptive OS-ELM (AOS-ELM). It is a single classifier scheme that works well to handle real drift, virtual drift, and hybrid drift. The AOS-ELM also works well for sudden drift and recurrent context change type. The scheme is a simple unified method implemented in simple lines of code. We evaluated AOS-ELM on regression and classification problem by using concept drift public data set (SEA and STAGGER) and other public data sets such as MNIST, USPS, and IDS. Experiments show that our method gives higher kappa value compared to the multiclassifier ELM ensemble. Even though AOS-ELM in practice does not need hidden nodes increase, we address some issues related to the increasing of the hidden nodes such as error condition and rank values. We propose taking the rank of the pseudoinverse matrix as an indicator parameter to detect “underfitting” condition. PMID:27594879

  4. Beyond Aspirations: Deploying the Capability Approach to Tackle the Under-Representation in Higher Education of Young People from Deprived Communities

    ERIC Educational Resources Information Center

    Campbell, Laurie Anne; McKendrick, John H.

    2017-01-01

    This paper re-examines the low participation of young people from deprived communities through the lens of the capability approach. A fundamental problem for tackling widening participation is that much of the thinking of policymakers is grounded on the flawed "poverty of aspiration thesis". This paper contends that Sen's [1992.…

  5. Tackling wicked problems: how theories of agency can provide new insights.

    PubMed

    Varpio, Lara; Aschenbrener, Carol; Bates, Joanna

    2017-04-01

    This paper reviews why and how theories of agency can be used as analytical lenses to help health professions education (HPE) scholars address our community's wicked problems. Wicked problems are those that resist clear problem statements, defy traditional analysis approaches, and refuse definitive resolution (e.g. student remediation, assessments of professionalism, etc.). We illustrate how theories of agency can provide new insights into such challenges by examining the application of these theories to one particular wicked problem in HPE: interprofessional education (IPE). After searching the HPE literature and finding that theories of agency had received little attention, we borrowed techniques from narrative literature reviews to search databases indexing a broad scope of disciplines (i.e. ERIC, Web of Science, Scopus, MEDLINE and PubMed) for publications (1994-2014) that: (i) examined agency, or (ii) incorporated an agency-informed analytical perspective. The lead author identified the theories of agency used in these articles, and reviewed the texts on agency cited therein and the original sources of each theory. We identified 10 theories of agency that we considered to be applicable to HPE's wicked problems. To select a subset of theories for presentation in this paper, we discussed each theory in relation to some of HPE's wicked problems. Through debate and reflection, we unanimously agreed on the applicability of a subset of theories for illuminating HPE's wicked problems. This subset is described in this paper. We present four theories of agency: Butler's post-structural formulation; Giddens' sociological formulation; cultural historical activity theory's formulation, and Bandura's social cognitive psychology formulation. We introduce each theory and apply each to the challenges of engaging in IPE. Theories of agency can inform HPE scholarship in novel and generative ways. Each theory offers new insights into the roots of wicked problems and means for

  6. The Effects of Verbal Instruction and Shaping to Improve Tackling by High School Football Players

    ERIC Educational Resources Information Center

    Harrison, Antonio M.; Pyles, David A.

    2013-01-01

    We evaluated verbal instruction and shaping using TAG (teaching with acoustical guidance) to improve tackling by 3 high school football players. Verbal instruction and shaping improved tackling for all 3 participants. In addition, performance was maintained as participants moved more quickly through the tackling procedure.

  7. The Future Problem Solving Program.

    ERIC Educational Resources Information Center

    Crabbe, Anne B.

    1989-01-01

    Describes the Future Problem Solving Program, in which students from the U.S. and around the world are tackling some complex challenges facing society, ranging from acid rain to terrorism. The program uses a creative problem solving process developed for business and industry. A sixth-grade toxic waste cleanup project illustrates the process.…

  8. Useful Metaphors for Tackling Problems in Teaching and Learning

    ERIC Educational Resources Information Center

    Schwartz, Marc S.; Fischer, Kurt W.

    2006-01-01

    Students learn important concepts and ways of thinking by building on their own actions and experiences. In much of higher education, the primacy of textbooks and the lectures that accompany them are inconsistent with the nature of student learning. Some students manage to learn despite the problems from this emphasis, but educators can do much…

  9. FOREWORD: Tackling inverse problems in a Banach space environment: from theory to applications Tackling inverse problems in a Banach space environment: from theory to applications

    NASA Astrophysics Data System (ADS)

    Schuster, Thomas; Hofmann, Bernd; Kaltenbacher, Barbara

    2012-10-01

    Inverse problems can usually be modelled as operator equations in infinite-dimensional spaces with a forward operator acting between Hilbert or Banach spaces—a formulation which quite often also serves as the basis for defining and analyzing solution methods. The additional amount of structure and geometric interpretability provided by the concept of an inner product has rendered these methods amenable to a convergence analysis, a fact which has led to a rigorous and comprehensive study of regularization methods in Hilbert spaces over the last three decades. However, for numerous problems such as x-ray diffractometry, certain inverse scattering problems and a number of parameter identification problems in PDEs, the reasons for using a Hilbert space setting seem to be based on conventions rather than an appropriate and realistic model choice, so often a Banach space setting would be closer to reality. Furthermore, non-Hilbertian regularization and data fidelity terms incorporating a priori information on solution and noise, such as general Lp-norms, TV-type norms, or the Kullback-Leibler divergence, have recently become very popular. These facts have motivated intensive investigations on regularization methods in Banach spaces, a topic which has emerged as a highly active research field within the area of inverse problems. Meanwhile some of the most well-known regularization approaches, such as Tikhonov-type methods requiring the solution of extremal problems, and iterative ones like the Landweber method, the Gauss-Newton method, as well as the approximate inverse method, have been investigated for linear and nonlinear operator equations in Banach spaces. Convergence with rates has been proven and conditions on the solution smoothness and on the structure of nonlinearity have been formulated. Still, beyond the existing results a large number of challenging open questions have arisen, due to the more involved handling of general Banach spaces and the larger variety

  10. Tackling Complex Emergency Response Solutions Evaluation Problems in Sustainable Development by Fuzzy Group Decision Making Approaches with Considering Decision Hesitancy and Prioritization among Assessing Criteria.

    PubMed

    Qi, Xiao-Wen; Zhang, Jun-Ling; Zhao, Shu-Ping; Liang, Chang-Yong

    2017-10-02

    In order to be prepared against potential balance-breaking risks affecting economic development, more and more countries have recognized emergency response solutions evaluation (ERSE) as an indispensable activity in their governance of sustainable development. Traditional multiple criteria group decision making (MCGDM) approaches to ERSE have been facing simultaneous challenging characteristics of decision hesitancy and prioritization relations among assessing criteria, due to the complexity in practical ERSE problems. Therefore, aiming at the special type of ERSE problems that hold the two characteristics, we investigate effective MCGDM approaches by hiring interval-valued dual hesitant fuzzy set (IVDHFS) to comprehensively depict decision hesitancy. To exploit decision information embedded in prioritization relations among criteria, we firstly define an fuzzy entropy measure for IVDHFS so that its derivative decision models can avoid potential information distortion in models based on classic IVDHFS distance measures with subjective supplementing mechanism; further, based on defined entropy measure, we develop two fundamental prioritized operators for IVDHFS by extending Yager's prioritized operators. Furthermore, on the strength of above methods, we construct two hesitant fuzzy MCGDM approaches to tackle complex scenarios with or without known weights for decision makers, respectively. Finally, case studies have been conducted to show effectiveness and practicality of our proposed approaches.

  11. Tackling Complex Emergency Response Solutions Evaluation Problems in Sustainable Development by Fuzzy Group Decision Making Approaches with Considering Decision Hesitancy and Prioritization among Assessing Criteria

    PubMed Central

    Qi, Xiao-Wen; Zhang, Jun-Ling; Zhao, Shu-Ping; Liang, Chang-Yong

    2017-01-01

    In order to be prepared against potential balance-breaking risks affecting economic development, more and more countries have recognized emergency response solutions evaluation (ERSE) as an indispensable activity in their governance of sustainable development. Traditional multiple criteria group decision making (MCGDM) approaches to ERSE have been facing simultaneous challenging characteristics of decision hesitancy and prioritization relations among assessing criteria, due to the complexity in practical ERSE problems. Therefore, aiming at the special type of ERSE problems that hold the two characteristics, we investigate effective MCGDM approaches by hiring interval-valued dual hesitant fuzzy set (IVDHFS) to comprehensively depict decision hesitancy. To exploit decision information embedded in prioritization relations among criteria, we firstly define an fuzzy entropy measure for IVDHFS so that its derivative decision models can avoid potential information distortion in models based on classic IVDHFS distance measures with subjective supplementing mechanism; further, based on defined entropy measure, we develop two fundamental prioritized operators for IVDHFS by extending Yager’s prioritized operators. Furthermore, on the strength of above methods, we construct two hesitant fuzzy MCGDM approaches to tackle complex scenarios with or without known weights for decision makers, respectively. Finally, case studies have been conducted to show effectiveness and practicality of our proposed approaches. PMID:28974045

  12. Specific tackling situations affect the biomechanical demands experienced by rugby union players.

    PubMed

    Seminati, Elena; Cazzola, Dario; Preatoni, Ezio; Trewartha, Grant

    2017-03-01

    Tackling in Rugby Union is an open skill which can involve high-speed collisions and is the match event associated with the greatest proportion of injuries. This study aimed to analyse the biomechanics of rugby tackling under three conditions: from a stationary position, with dominant and non-dominant shoulder, and moving forward, with dominant shoulder. A specially devised contact simulator, a 50-kg punch bag instrumented with pressure sensors, was translated towards the tackler (n = 15) to evaluate the effect of laterality and tackling approach on the external loads absorbed by the tackler, on head and trunk motion, and on trunk muscle activities. Peak impact force was substantially higher in the stationary dominant (2.84 ± 0.74 kN) than in the stationary non-dominant condition (2.44 ± 0.64 kN), but lower than in the moving condition (3.40 ± 0.86 kN). Muscle activation started on average 300 ms before impact, with higher activation for impact-side trapezius and non-impact-side erector spinae and gluteus maximus muscles. Players' technique for non-dominant-side tackles was less compliant with current coaching recommendations in terms of cervical motion (more neck flexion and lateral bending in the stationary non-dominant condition) and players could benefit from specific coaching focus on non-dominant-side tackles.

  13. Evaluating behavioral skills training to teach safe tackling skills to youth football players.

    PubMed

    Tai, Sharayah S M; Miltenberger, Raymond G

    2017-10-01

    With concussion rates on the rise for football players, there is a need for further research to increase skills and decrease injuries. Behavioral skills training is effective in teaching a wide variety of skills but has yet to be studied in the sports setting. We evaluated behavioral skills training to teach safer tackling techniques to six participants from a Pop Warner football team. Safer tackling techniques increased during practice and generalized to games for the two participants who had opportunities to tackle in games. © 2017 Society for the Experimental Analysis of Behavior.

  14. Tackling 'wicked' health promotion problems: a New Zealand case study.

    PubMed

    Signal, Louise N; Walton, Mat D; Ni Mhurchu, Cliona; Maddison, Ralph; Bowers, Sharron G; Carter, Kristie N; Gorton, Delvina; Heta, Craig; Lanumata, Tolotea S; McKerchar, Christina W; O'Dea, Des; Pearce, Jamie

    2013-03-01

    This paper reports on a complex environmental approach to addressing 'wicked' health promotion problems devised to inform policy for enhancing food security and physical activity among Māori, Pacific and low-income people in New Zealand. This multi-phase research utilized literature reviews, focus groups, stakeholder workshops and key informant interviews. Participants included members of affected communities, policy-makers and academics. Results suggest that food security and physical activity 'emerge' from complex systems. Key areas for intervention include availability of money within households; the cost of food; improvements in urban design and culturally specific physical activity programmes. Seventeen prioritized intervention areas were explored in-depth and recommendations for action identified. These include healthy food subsidies, increasing the statutory minimum wage rate and enhancing open space and connectivity in communities. This approach has moved away from seeking individual solutions to complex social problems. In doing so, it has enabled the mapping of the relevant systems and the identification of a range of interventions while taking account of the views of affected communities and the concerns of policy-makers. The complex environmental approach used in this research provides a method to identify how to intervene in complex systems that may be relevant to other 'wicked' health promotion problems.

  15. Tackling Noncommunicable Diseases in Africa: Caveat Lector

    ERIC Educational Resources Information Center

    Mensah, George A.

    2016-01-01

    Noncommunicable disease (NCD), principally cardiovascular diseases, cancer, chronic lung disease, and diabetes, constitutes the major cause of death worldwide. Evidence of a continuing increase in the global burden of these diseases has generated recent urgent calls for global action to tackle and reduce related death and disability. Because the…

  16. Advice to Policy Makers Who Would Tackle Syria: The Problem with Problem Solving

    DTIC Science & Technology

    2014-01-01

    consensus on the specific way forward in Syria, there is one thing most do agree on; Syria is complex. It is complex in the familiar use of that term...SYRIA SYRIA SUPPLEMENTAL FEATURES | 125 strengthen stabilizing loops (ones that keep things from getting worse) or virtuous cycles (ones that make... things worse and worse over time). Second, and more importantly, affecting patterns can be the key to solving the problem of strained or insufficient

  17. Toward Modeling the Intrinsic Complexity of Test Problems

    ERIC Educational Resources Information Center

    Shoufan, Abdulhadi

    2017-01-01

    The concept of intrinsic complexity explains why different problems of the same type, tackled by the same problem solver, can require different times to solve and yield solutions of different quality. This paper proposes a general four-step approach that can be used to establish a model for the intrinsic complexity of a problem class in terms of…

  18. Tackling the challenges of matching biomedical ontologies.

    PubMed

    Faria, Daniel; Pesquita, Catia; Mott, Isabela; Martins, Catarina; Couto, Francisco M; Cruz, Isabel F

    2018-01-15

    Biomedical ontologies pose several challenges to ontology matching due both to the complexity of the biomedical domain and to the characteristics of the ontologies themselves. The biomedical tracks in the Ontology Matching Evaluation Initiative (OAEI) have spurred the development of matching systems able to tackle these challenges, and benchmarked their general performance. In this study, we dissect the strategies employed by matching systems to tackle the challenges of matching biomedical ontologies and gauge the impact of the challenges themselves on matching performance, using the AgreementMakerLight (AML) system as the platform for this study. We demonstrate that the linear complexity of the hash-based searching strategy implemented by most state-of-the-art ontology matching systems is essential for matching large biomedical ontologies efficiently. We show that accounting for all lexical annotations (e.g., labels and synonyms) in biomedical ontologies leads to a substantial improvement in F-measure over using only the primary name, and that accounting for the reliability of different types of annotations generally also leads to a marked improvement. Finally, we show that cross-references are a reliable source of information and that, when using biomedical ontologies as background knowledge, it is generally more reliable to use them as mediators than to perform lexical expansion. We anticipate that translating traditional matching algorithms to the hash-based searching paradigm will be a critical direction for the future development of the field. Improving the evaluation carried out in the biomedical tracks of the OAEI will also be important, as without proper reference alignments there is only so much that can be ascertained about matching systems or strategies. Nevertheless, it is clear that, to tackle the various challenges posed by biomedical ontologies, ontology matching systems must be able to efficiently combine multiple strategies into a mature matching

  19. Tour of a simple trigonometry problem

    NASA Astrophysics Data System (ADS)

    Poon, Kin-Keung

    2012-06-01

    This article focuses on a simple trigonometric problem that generates a strange phenomenon when different methods are applied to tackling it. A series of problem-solving activities are discussed, so that students can be alerted that the precision of diagrams is important when solving geometric problems. In addition, the problem-solving plan was implemented in a high school and the results indicated that students are relatively weak in problem-solving abilities but they understand and appreciate the thinking process in different stages and steps of the activities.

  20. Tackling drug and alcohol misuse in Brazil: priorities and challenges for nurses.

    PubMed

    Rassool, G H; Villar-Luis, M

    2004-12-01

    To provide an overview of the extent of drug and alcohol misuse in Brazil and the policies and approaches in tackling substance misuse. An examination of the challenges facing the nursing profession in working with substance misusers is presented. Alcohol, cocaine, and cannabis are the most commonly misused psychoactive substances in Brazil. One of the biggest public health problems is the interface between the misuse of psychoactive substances and HIV prevalence and other sexually transmitted diseases. Findings from a recent study suggest that undergraduate nurses in Brazil are not adequately prepared in the care and management of substance misuse problems. The nursing profession in Brazil faces numerous challenges in the development of professional competence of nurses in this field. A strategy proposed is the creation of regional centres in Brazil to study the integration of substance use and misuse in the nursing undergraduate curriculum and the giving of specific support in teaching and research to nurse teachers. Nurses have a key role to play in the early recognition, assessment, prevention, and treatment of substance misuse.

  1. Tackling a Problem School.

    ERIC Educational Resources Information Center

    Lowe, Robert B.; Gervais, Robert L.

    1984-01-01

    Case study of a new principal who turns around an elementary school with a misbehaving student body and and apathetic staff by setting, publicizing, and consistently enforcing clear rules; documenting infractions; involving parents; encouraging student responsibility; and requiring lesson plans. (DCS)

  2. Problem Solution Project: Transforming Curriculum and Empowering Urban Students and Teachers

    ERIC Educational Resources Information Center

    Jarrett, Olga S.; Stenhouse, Vera

    2011-01-01

    This article presents findings of 6 years of implementing a Problem Solution Project, an assignment influenced by service learning, problem-based learning, critical theory, and critical pedagogy whereby teachers help children tackle real problems. Projects of 135 teachers in an urban certification/master's program were summarized by cohort year…

  3. Identification of a hybridization window that facilitates sizeable reductions of pollen-mediated gene flow in spring wheat.

    PubMed

    Willenborg, Christian J; Brûlé-Babel, Anita L; Van Acker, Rene C

    2010-06-01

    Transgenic wheat (Triticum aestivum L.) with improved agronomic traits is currently being field-tested. Gene flow in space is well-documented, but isolation in time has not received comparable attention. Here, we report the results of a field experiment that investigated reductions in intraspecific gene flow associated with temporal isolation of flowering between T. aestivum conspecifics. Pollen-mediated gene flow (PMGF) between an imazamox-resistant (IR) volunteer wheat population and a non-IR spring wheat crop was assessed over a range of volunteer emergence timings and plant population densities that collectively promoted flowering asynchrony. Natural hybridization events between the two populations were detected by phenotypically scoring plants in F(1) populations followed by verification with Mendelian segregation ratios in the F(1:2) lines. Based on the examination of >545,000 seedlings, we identified a hybridization window in spring wheat approximately 125 growing degree-days (GDD) in length. We found a sizeable reduction (two- to four-fold) in gene flow frequencies when flowering occurred outside of this window. The hybridization window identified in this research also will serve to temporally isolate neighboring wheat crops. However, strict control of volunteer populations or spatial isolation of neighbouring crops emerging within a 125 GDD hybridization window will be necessary to maintain low frequencies of PMGF in spring wheat fields. The model developed herein also is likely to be applicable to other wind-pollinated species.

  4. Solving the Sailors and the Coconuts Problem via Diagrammatic Approach

    ERIC Educational Resources Information Center

    Man, Yiu-Kwong

    2010-01-01

    In this article, we discuss how to use a diagrammatic approach to solve the classic sailors and the coconuts problem. It provides us an insight on how to tackle this type of problem in a novel and intuitive way. This problem-solving approach will be found useful to mathematics teachers or lecturers involved in teaching elementary number theory,…

  5. [Family Health Strategies to tackle violence involving adolescents].

    PubMed

    Vieira Netto, Moysés Francisco; Deslandes, Suely Ferreira

    2016-05-01

    The Family Health Strategy (FHS) has an acknowledged potential for the promotion of health and the prevention of violence. This is an integrative bibliographic review with the aim of evaluating the performance of FHS professionals in tackling and preventing violence involving adolescents. It is an integrative review of dissertations and theses on healthcare published from 1994 to 2014. The collection of 17 dissertations and 2 doctoral theses reveals that these studies are recent. The FHS professionals acknowledge the vulnerability of adolescents to inflicting and being subject to violence, however the FHS proves ineffective in tackling and preventing such violence. The predominance of the medical technical care model, the deficiencies in Public Health education in professional training and the lack of institutional support are seen as the main obstacles. Many of these professionals are unaware of the files for notification of violence. The existence of family violence and criminal groups were the aspects most mentioned in the territories. The social representation of adolescents as being "problematic" and the lack of ESF actions that promote an increase youth leadership and empowerment were clearly detected.

  6. Which Women Were Executed for Witchcraft? And Which Pupils Cared? Low-Attaining Year 8 Use Fiction to Tackle Three Demons: Extended Reading, Diversity and Causation

    ERIC Educational Resources Information Center

    Worth, Paula

    2011-01-01

    Paula Worth was concerned that her low-attaining set were only going through the motions when tackling causal explanation. Identifying, prioritising and weighing causes seemed an empty routine rather than a fascinating puzzle engaging intellect and imagination. She was also concerned that her usual efforts to solve this problem had been misplaced.…

  7. Mechanisms and Factors Associated With Tackle-Related Injuries in South African Youth Rugby Union Players.

    PubMed

    Burger, Nicholas; Lambert, Mike Ian; Viljoen, Wayne; Brown, James Craig; Readhead, Clint; den Hollander, Steve; Hendricks, Sharief

    2017-02-01

    The majority of injuries in rugby union occur during tackle events. The mechanisms and causes of these injuries are well established in senior rugby union. To use information from an injury database and assess video footage of tackle-related injuries in youth rugby union matches to identify environmental factors and mechanisms that are potentially confounding to these injuries. Descriptive epidemiological study. Injury surveillance was conducted at the under-18 Craven Week rugby tournament. Tackle-related injury information was used to identify injury events in match video footage (role-matched noninjury tackle events were identified for the cohort of injured players). Events were coded using match situational variables (precontact, contact, and postcontact). Relative risk ratio (RRR; ratio of probability of an injury or noninjury outcome occurring when a characteristic was observed) was reported by use of logistic regression. In comparison with the first quarter, injury risk was greater in the third (RRR = 9.75 [95% CI, 1.71-55.64]; P = .010) and fourth quarters (RRR = 6.97 [95% CI, 1.09-44.57]; P = .040) for ball carriers and in the fourth quarter (RRR = 9.63 [95% CI, 1.94-47.79]; P = .006) for tacklers. Ball carriers were less likely to be injured when they were aware of impending contact (RRR = 0.14 [95% CI, 0.03-0.66]; P = .012) or when they executed a moderate fend (hand-off) (RRR = 0.22 [95% CI, 0.06-0.84]; P = .026). Tacklers were less likely to be injured when performing shoulder tackles (same side as leading leg) in comparison to an arm-only tackle (RRR = 0.02 [95% CI, 0.001-0.79]; P = .037). Ball carriers (RRR = 0.09 [95% CI, 0.01-0.89]; P = .040) and tacklers (RRR = 0.02 [95% CI, 0.001-0.32]; P =.006) were less likely to be injured when initial contact was made with the tackler's shoulder/arm instead of his head/neck. The relative risk of tackle-related injury was higher toward the end of matches. Incorrect technique may contribute to increased injury

  8. Local Communities and Schools Tackling Sustainability and Climate Change

    ERIC Educational Resources Information Center

    Flowers, Rick; Chodkiewicz, Andrew

    2009-01-01

    Local communities and their schools remain key sites for actions tackling issues of sustainability and climate change. A government-funded environmental education initiative, the Australian Sustainable Schools Initiative (AuSSI), working together with state based Sustainable Schools Programs (SSP), has the ability to support the development of…

  9. Tackling U.S. energy challenges and opportunities: preliminary policy recommendations for enhancing energy innovation in the United States

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Anadon, Laura Diaz; Gallagher, Kelly Sims; Bunn, Matthew

    2009-02-18

    The report offers preliminary recommendations for near-term actions to strengthen the U.S. effort to develop and deploy advanced energy technologies. The report comes as the Obama Administration and the 111th U.S. Congress face enormous challenges and opportunities in tackling the pressing security, economic, and environmental problems posed by the energy sector. Improving the technologies of energy supply and end-use is a prerequisite for surmounting these challenges in a timely and cost-effective way, and this report elaborates on how policy can support develop of these important energy technologies.

  10. 2. VIEW OF BLOCK AND TACKLE FOR MOVING CEDAR LOGS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. VIEW OF BLOCK AND TACKLE FOR MOVING CEDAR LOGS FROM POND TO JACK LADDER--AN ENDLESS CHAIN CONVEYOR THAT MOVES LOGS INTO MILL - Lester Shingle Mill, 1602 North Eighteenth Street, Sweet Home, Linn County, OR

  11. Tackling childhood obesity: the importance of understanding the context.

    PubMed

    Knai, Cécile; McKee, Martin

    2010-12-01

    Recommendations to tackle major health problems such as childhood obesity may not be appropriate if they fail to take account of the prevailing socio-political, cultural and economic context. We describe the development and application of a qualitative risk analysis approach to identify non-scientific considerations framing the policy response to obesity in Denmark and Latvia. Interviews conducted with key stakeholders in Denmark and Latvia, undertaken following a review of relevant literature on obesity and national policies. A qualitative risk analysis model was developed to help explain the findings in the light of national context. Non-scientific considerations that appeared to influence the response to obesity include the perceived relative importance of childhood obesity; the nature of stakeholder relations and its impact on decision-making; the place of obesity on the policy agenda; the legitimacy of the state to act for population health and views on alliances between public and private sectors. Better recognition of the exogenous factors affecting policy-making may lead to a more adequate policy response. The development and use of a qualitative risk analysis model enabled a better understanding of the contextual factors and processes influencing the response to childhood obesity in each country.

  12. 46 CFR 184.300 - Ground tackle and mooring lines.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Ground tackle and mooring lines. 184.300 Section 184.300 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) VESSEL CONTROL AND MISCELLANEOUS SYSTEMS AND EQUIPMENT Mooring and Towing Equipment § 184.300...

  13. Tackling antibiotic resistance: the environmental framework.

    PubMed

    Berendonk, Thomas U; Manaia, Célia M; Merlin, Christophe; Fatta-Kassinos, Despo; Cytryn, Eddie; Walsh, Fiona; Bürgmann, Helmut; Sørum, Henning; Norström, Madelaine; Pons, Marie-Noëlle; Kreuzinger, Norbert; Huovinen, Pentti; Stefani, Stefania; Schwartz, Thomas; Kisand, Veljo; Baquero, Fernando; Martinez, José Luis

    2015-05-01

    Antibiotic resistance is a threat to human and animal health worldwide, and key measures are required to reduce the risks posed by antibiotic resistance genes that occur in the environment. These measures include the identification of critical points of control, the development of reliable surveillance and risk assessment procedures, and the implementation of technological solutions that can prevent environmental contamination with antibiotic resistant bacteria and genes. In this Opinion article, we discuss the main knowledge gaps, the future research needs and the policy and management options that should be prioritized to tackle antibiotic resistance in the environment.

  14. Return to play guidelines cannot solve the football-related concussion problem.

    PubMed

    Johnson, L Syd M

    2012-04-01

    High school football players are the single largest cohort of athletes playing tackle football, and account for the majority of sport-related concussions. Return to play guidelines (RTPs) have emerged as the preferred approach for addressing the problem of sport-related concussion in youth athletes. This article reviews evidence of the risks and effects of football-related concussion and subconcussive brain trauma, as well as the effectiveness of RTPs as a preventative measure. Literature review utilized PubMed and Google Scholar, using combinations of the search terms "football,"sports,"concussion,"Chronic Traumatic Encephalopathy,"athlete,"youth," and "pediatric." Literature review emphasized medical journals and primary neuroscientific research on sport-related concussion and concussion recovery, particularly in youth athletes. Sport-related concussion is a significant problem among student athletes. Student athletes are more vulnerable to concussion, and at risk of neurocognitive deficits lasting a year or more, with serious effects on academic and athletic performance. RTPs do little to address the problem of sport-related concussion or the chronic damage caused by subconcussive brain trauma. Emphasizing RTPs as the solution to the concussion problem in tackle football risks neglecting genuine reforms that would prevent concussions. More effective concussion prevention is needed. Eliminating tackling from school football for youth under 16 is recommended to reduce concussions. Additional modifications to football are recommended to enhance safety and reduce brain trauma at all levels of play. © 2012, American School Health Association.

  15. Promoting healthy diets and tackling obesity and diet-related chronic diseases: what are the agricultural policy levers?

    PubMed

    Hawkes, Corinna

    2007-06-01

    Diet-related chronic diseases are now a serious global public health problem. Public health groups are calling for the agricultural sector to play a greater role in tackling the threat. To identify potential points of policy intervention in the agricultural sector that could be leveraged to promote healthy diets and tackle obesity and diet-related chronic diseases. A review of the literature on the dietary implications of agriculture, a conceptual analysis of the issues, and the identification of relevant examples. There are two main potential points of intervention in the agricultural sector that could be leveraged to promote healthy diets: agricultural policies and agricultural production practices. Agricultural policies and practices affect diet through their influence on food availability, price, and nutrient quality, which in turn affects food choices available to consumers. Agricultural policies amenable to intervention include input, production, and trade policies; agricultural production practices amenable to intervention include crop breeding, crop fertilization practices, livestock-feeding practices, and crop systems diversity. It is well-known that agricultural policies and production practices influence what farmers choose to grow. Agricultural policies and production practices could also play a role in influencing what consumers choose to eat. To identify how agricultural policies and practices can usefully contribute toward promoting healthy diets and tackling obesity and diet-related chronic diseases, health policymakers need to examine whether current agricultural policies and production practices are contributing to-or detracting from-efforts to attain dietary goals; where and how could agricultural intervention help achieve dietary goals; and whether there are trade-offs between these interventions and other important concerns, such as undernutrition and the livelihoods of agricultural producers. Given the potential of agriculture to contribute to

  16. Quantitative nanoscopy: Tackling sampling limitations in (S)TEM imaging of polymers and composites.

    PubMed

    Gnanasekaran, Karthikeyan; Snel, Roderick; de With, Gijsbertus; Friedrich, Heiner

    2016-01-01

    Sampling limitations in electron microscopy questions whether the analysis of a bulk material is representative, especially while analyzing hierarchical morphologies that extend over multiple length scales. We tackled this problem by automatically acquiring a large series of partially overlapping (S)TEM images with sufficient resolution, subsequently stitched together to generate a large-area map using an in-house developed acquisition toolbox (TU/e Acquisition ToolBox) and stitching module (TU/e Stitcher). In addition, we show that quantitative image analysis of the large scale maps provides representative information that can be related to the synthesis and process conditions of hierarchical materials, which moves electron microscopy analysis towards becoming a bulk characterization tool. We demonstrate the power of such an analysis by examining two different multi-phase materials that are structured over multiple length scales. Copyright © 2015 Elsevier B.V. All rights reserved.

  17. Addressing Complex Challenges through Adaptive Leadership: A Promising Approach to Collaborative Problem Solving

    ERIC Educational Resources Information Center

    Nelson, Tenneisha; Squires, Vicki

    2017-01-01

    Organizations are faced with solving increasingly complex problems. Addressing these issues requires effective leadership that can facilitate a collaborative problem solving approach where multiple perspectives are leveraged. In this conceptual paper, we critique the effectiveness of earlier leadership models in tackling complex organizational…

  18. Waste collection in developing countries - Tackling occupational safety and health hazards at their source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bleck, Daniela, E-mail: bleck.daniela@baua.bund.de; Wettberg, Wieland, E-mail: wettberg.wieland@baua.bund.de

    2012-11-15

    Waste management procedures in developing countries are associated with occupational safety and health risks. Gastro-intestinal infections, respiratory and skin diseases as well as muscular-skeletal problems and cutting injuries are commonly found among waste workers around the globe. In order to find efficient, sustainable solutions to reduce occupational risks of waste workers, a methodological risk assessment has to be performed and counteractive measures have to be developed according to an internationally acknowledged hierarchy. From a case study in Addis Ababa, Ethiopia suggestions for the transferral of collected household waste into roadside containers are given. With construction of ramps to dump collectedmore » household waste straight into roadside containers and an adaptation of pushcarts and collection procedures, the risk is tackled at the source.« less

  19. Tackling emerging fungal threats to animal health, food security and ecosystem resilience.

    PubMed

    Fisher, Matthew C; Gow, Neil A R; Gurr, Sarah J

    2016-12-05

    Emerging infections caused by fungi have become a widely recognized global phenomenon. Their notoriety stems from their causing plagues and famines, driving species extinctions, and the difficulty in treating human mycoses alongside the increase of their resistance to antifungal drugs. This special issue comprises a collection of articles resulting from a Royal Society discussion meeting examining why pathogenic fungi are causing more disease now than they did in the past, and how we can tackle this rapidly emerging threat to the health of plants and animals worldwide.This article is part of the themed issue 'Tackling emerging fungal threats to animal health, food security and ecosystem resilience'. © 2016 The Author(s).

  20. We must tackle population problems.

    PubMed

    Hironaka, W

    1992-03-01

    Thank you Mr. Chairman, for the opportunity to speak out not only as a Japanese parliamentarian, but also as a member of GLOBE International, Global Legislators Organization for a Balanced Environment, consisting of legislators from the US Congress, EC Parliament, USSR Assembly and Japanese Diet who have joined together to compare, improve and coordinate our respective legislative activities in an effort to effectively address the complex issues surrounding environment and development. Mr. Chairman, world population--which reached 5.4 billion in mid-1991--is growing exponentially. According to 1 UNFPA report 3 people are born every second, a total of 250,000 people every day or 95-100 million people every year. At this rate, world population will reach 6.4 billion by year 2001, and if this rate continues to go unchecked, world population will reach 14-15 billion by the end of the 21st century. GLOBE is highly aware of the relationship between rapidly growing human populations, environmental degradation and sustainable development. We urge UNCED negotiators to address population growth rates and the integrally linked concerns of resource consumption levels, particularly in the industrialized world, in their search for solutions to the conflict between environment and development. Negotiators should also seriously consider ways in which to broaden educational and economic opportunities for women to ease population growth rates, and to alleviate poverty and stresses on the environment that result from population pressures. Social and economic factors must be integrated into population planning. It is saddening to note that almost 40,000 children die every day due to malnutrition, lack of fresh water and access to resources. Over 100 million children do not receive a primary education. Mr. Chairman, worldwide demand for a range of family planning services is increasing faster than supply. Recent studies indicate that if quality family planning information, training and services were made readily available by government and other groups, population rates would drop to manageable levels. Widespread access to family planning services is essential to population stabilization. The health of mothers, children and general quality of life is also improved through the implementation of family planning programs. At the present time many women cannot make use of the limited available services because of cultural constraints, lack of status and self-confidence. Unless complementary efforts are made to expand economic and educational opportunities for women, family planning and other reproductive health services will not reach their full potential for stabilizing population. Although family planning is an individual decision, and implementation of population programs is a sovereign matter in each country, I would urge developed countries to help their neighbors in developing countries who are in need of support for family planning and health services. Investment in family planning programs is 1 of the best ways to contribute to environmental protection and improvement. A greater portion of our foreign aid monies should be allocated for direct population assistance programs that will reach people at the grassroots level. To achieve this, a cooperative working relationship with local nongovernmental organization (NGOs) is essential. The members of GLOBE hope to facilitate cooperation between NGOs and governments so that we might stabilize human population. full text

  1. Tackling misconceptions in geometrical optics

    NASA Astrophysics Data System (ADS)

    Ceuppens, S.; Deprez, J.; Dehaene, W.; De Cock, M.

    2018-07-01

    To improve the teaching and learning materials for a curriculum it is important to incorporate the findings from educational research. In light of this, we present creative exercises and experiments to elicit, confront and resolve misconceptions in geometrical optics. Since ray diagrams can be both the cause and the solution for many misconceptions we focus strongly on improving understanding of this tool to solve and understand optical phenomena. Through a combination of a conceptual understanding programme (CUP) and provocative exercises with ray diagrams we aim to elicit conceptual or cognitive conflict and exploit this to tackle misconceptions and increase students’ conceptual understanding through inquiry. We describe exercises for image formation by a plane mirror, image formation by a convex lens and indirect and direct observation of a real image formed by a convex lens as examples of our approach.

  2. Promoting Collaborative Problem-Solving Skills in a Course on Engineering Grand Challenges

    ERIC Educational Resources Information Center

    Zou, Tracy X. P.; Mickleborough, Neil C.

    2015-01-01

    The ability to solve problems with people of diverse backgrounds is essential for engineering graduates. A course on engineering grand challenges was designed to promote collaborative problem-solving (CPS) skills. One unique component is that students need to work both within their own team and collaborate with the other team to tackle engineering…

  3. The impact of tackle football injuries on the American healthcare system with a neurological focus.

    PubMed

    McGinity, Michael J; Grandhi, Ramesh; Michalek, Joel E; Rodriguez, Jesse S; Trevino, Aron M; McGinity, Ashley C; Seifi, Ali

    2018-01-01

    Recent interest in the study of concussion and other neurological injuries has heightened awareness of the medical implications of American tackle football injuries amongst the public. Using the National Emergency Department Sample (NEDS) and the National Inpatient Sample (NIS), the largest publicly available all-payer emergency department and inpatient healthcare databases in the United States, we sought to describe the impact of tackle football injuries on the American healthcare system by delineating injuries, specifically neurological in nature, suffered as a consequence of tackle football between 2010 and 2013. The NEDS and NIS databases were queried to collect data on all patients presented to the emergency department (ED) and/or were admitted to hospitals with an ICD code for injuries related to American tackle football between the years 2010 and 2013. Subsequently those with football-related neurological injuries were abstracted using ICD codes for concussion, skull/face injury, intracranial injury, spine injury, and spinal cord injury (SCI). Patient demographics, length of hospital stay (LOS), cost and charge data, neurosurgical interventions, hospital type, and disposition were collected and analyzed. A total of 819,000 patients presented to EDs for evaluation of injuries secondary to American tackle football between 2010 and 2013, with 1.13% having injuries requiring inpatient admission (average length of stay 2.4 days). 80.4% of the ED visits were from the pediatric population. Of note, a statistically significant increase in the number of pediatric concussions over time was demonstrated (OR = 1.1, 95% CI 1.1 to 1.2). Patients were more likely to be admitted to trauma centers, teaching hospitals, the south or west regions, or with private insurance. There were 471 spinal cord injuries and 1,908 total spine injuries. Ten patients died during the study time period. The combined ED and inpatient charges were $1.35 billion. Injuries related to tackle

  4. The impact of tackle football injuries on the American healthcare system with a neurological focus

    PubMed Central

    McGinity, Michael J.; Grandhi, Ramesh; Michalek, Joel E.; Rodriguez, Jesse S.; Trevino, Aron M.; McGinity, Ashley C.

    2018-01-01

    Background Recent interest in the study of concussion and other neurological injuries has heightened awareness of the medical implications of American tackle football injuries amongst the public. Objective Using the National Emergency Department Sample (NEDS) and the National Inpatient Sample (NIS), the largest publicly available all-payer emergency department and inpatient healthcare databases in the United States, we sought to describe the impact of tackle football injuries on the American healthcare system by delineating injuries, specifically neurological in nature, suffered as a consequence of tackle football between 2010 and 2013. Methods The NEDS and NIS databases were queried to collect data on all patients presented to the emergency department (ED) and/or were admitted to hospitals with an ICD code for injuries related to American tackle football between the years 2010 and 2013. Subsequently those with football-related neurological injuries were abstracted using ICD codes for concussion, skull/face injury, intracranial injury, spine injury, and spinal cord injury (SCI). Patient demographics, length of hospital stay (LOS), cost and charge data, neurosurgical interventions, hospital type, and disposition were collected and analyzed. Results A total of 819,000 patients presented to EDs for evaluation of injuries secondary to American tackle football between 2010 and 2013, with 1.13% having injuries requiring inpatient admission (average length of stay 2.4 days). 80.4% of the ED visits were from the pediatric population. Of note, a statistically significant increase in the number of pediatric concussions over time was demonstrated (OR = 1.1, 95% CI 1.1 to 1.2). Patients were more likely to be admitted to trauma centers, teaching hospitals, the south or west regions, or with private insurance. There were 471 spinal cord injuries and 1,908 total spine injuries. Ten patients died during the study time period. The combined ED and inpatient charges were $1

  5. The Role of Empathy in Preparing Teachers to Tackle Bullying

    ERIC Educational Resources Information Center

    Murphy, Helena; Tubritt, John; Norman, James O'Higgins

    2018-01-01

    Much research on bullying behaviour in schools among students has been carried out since the 1970's, when Olweus started a large-scale project in Norway which is now generally regarded as the first scientific study on bullying. Yet, there has been little research on how teachers respond to reports of bullying and tackle bullying behaviour in…

  6. The evolution of policy and actions to tackle obesity in England.

    PubMed

    Jebb, S A; Aveyard, P N; Hawkes, C

    2013-11-01

    Tackling obesity has been a policy priority in England for more than 20 years. Two formal government strategies on obesity in 2008 and 2011 drew together a range of actions and developed new initiatives to fill perceived gaps. Today, a wide range of policies are in place, including support for breastfeeding and healthy weaning practices, nutritional standards in schools, restrictions on marketing foods high in fat, sugar and salt to children, schemes to boost participation in sport, active travel plans, and weight management services. Data from annual surveys show that the rate of increase in obesity has attenuated in recent years, but has not yet been reversed. This paper considers the actions taken and what is known about the impact of individual policies and the overarching strategy to tackle obesity in England. © 2013 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of the International Association for the Study of Obesity.

  7. Problem Analysis: The First Step in Prevention Planning. A Prevention 101 Series Publication

    ERIC Educational Resources Information Center

    DeJong, William

    2009-01-01

    Student alcohol and other drug abuse and violence (AODV) still reign as the most serious social problems faced by U.S. institutions of higher education. To tackle these problems, campus administrators--working in conjunction with partners from the surrounding community--need to put in place an integrated set of strategies that address the mix of…

  8. Tackling Threats and Future Problems of Multidrug-Resistant Bacteria.

    PubMed

    Medina, Eva; Pieper, Dietmar Helmut

    With the advent of the antibiotic era, the overuse and inappropriate consumption and application of antibiotics have driven the rapid emergence of multidrug-resistant pathogens. Antimicrobial resistance increases the morbidity, mortality, length of hospitalization and healthcare costs. Among Gram-positive bacteria, Staphylococcus aureus (MRSA) and multidrug-resistant (MDR) Mycobacterium tuberculosis, and among the Gram-negative bacteria, extended-spectrum beta-lactamase (ESBLs)-producing bacteria have become a major global healthcare problem in the 21st century. The pressure to use antibiotics guarantees that the spread and prevalence of these as well as of future emerging multidrug-resistant pathogens will be a persistent phenomenon. The unfeasibility of reversing antimicrobial resistance back towards susceptibility and the critical need to treat bacterial infection in modern medicine have burdened researchers and pharmaceutical companies to develop new antimicrobials effective against these difficult-to-treat multidrug-resistant pathogens. However, it can be anticipated that antibiotic resistance will continue to develop more rapidly than new agents to treat these infections become available and a better understanding of the molecular, evolutionary and ecological mechanisms governing the spread of antibiotic resistance is needed. The only way to curb the current crisis of antimicrobial resistance will be to develop entirely novel strategies to fight these pathogens such as combining antimicrobial drugs with other agents that counteract and obstruct the antibiotic resistant mechanisms expressed by the pathogen. Furthermore, as many antibiotics are often inappropriately prescribed, a more personalized approach based on precise diagnosis tools will ensure that proper treatments can be promptly applied leading to more targeted and effective therapies. However, in more general terms, also the overall use and release of antibiotics in the environment needs to be

  9. Encouraging the Use of Technology in Problem-Solving: Some Examples from an Initial Teacher Education Programme

    ERIC Educational Resources Information Center

    Lopez-Real, Francis; Lee, Arthur

    2006-01-01

    As part of a module on mathematical problem solving in an Initial Teacher Education programme, the student teachers are encouraged to produce alternative solutions to the problems they tackle and, in particular, to consider whether ICT can help. In this paper we discuss a number of unusual solutions produced for some of the problems, specifically…

  10. The use of multi-criteria decision analysis to tackle waste management problems: a literature review.

    PubMed

    Achillas, Charisios; Moussiopoulos, Nicolas; Karagiannidis, Avraam; Banias, Georgias; Perkoulidis, George

    2013-02-01

    Problems in waste management have become more and more complex during recent decades. The increasing volumes of waste produced and social environmental consciousness present prominent drivers for environmental managers towards the achievement of a sustainable waste management scheme. However, in practice, there are many factors and influences - often mutually conflicting - criteria for finding solutions in real-life applications. This paper presents a review of the literature on multi-criteria decision aiding in waste management problems for all reported waste streams. Despite limitations, which are clearly stated, most of the work published in this field is reviewed. The present review aims to provide environmental managers and decision-makers with a thorough list of practical applications of the multi-criteria decision analysis techniques that are used to solve real-life waste management problems, as well as the criteria that are mostly employed in such applications according to the nature of the problem under study. Moreover, the paper explores the advantages and disadvantages of using multi-criteria decision analysis techniques in waste management problems in comparison to other available alternatives.

  11. Agricultural vehicles and rural road safety: tackling a persistent problem.

    PubMed

    Jaarsma, Catharinus F; De Vries, Jasper R

    2014-01-01

    Crashes involving agricultural vehicles (AVs) on public roads are an increasing road safety problem. We aim to analyze developments in the appearance and severity of these accidents, identify influencing factors, and draw lessons for possible interventions for accident prevention within the context of modern mechanized agriculture. To analyze developments in the appearance of accidents we use a subset of accidents with AVs involved on public roads in The Netherlands aggregated per year for 1987-2010. To identify and explore preventive measures we use an in-depth study of the Dutch Safety Board. With a study of international literature we put our findings in a wider context. During this time span, Dutch annual averages show 15 registered fatal accidents involving AVs, 93 with hospitalization and 137 with slight injuries. For nonfatal accidents, the numbers are decreasing over time. This decrease is proportionate to the reduction in the total number of traffic victims. For fatalities, however, the number is stable, increasing its proportion in all traffic fatalities from 1 in 1987 to 2 percent in 2010. Related to the number of inhabitants, this number is 2 times the value in the UK and 3 times the value in the United States. Influencing factors can be related to the 3 road system components (AV, driver, and infrastructure). Weak points for AVs are the view from the driver's seat, visibility at night, permitted vehicle width, and crash aggressivity (large kinetic energy of the AV) that is transferred to other road users in case of a collision. Important factors identified for the driver are poor risk perception and high risk acceptance, in combination with speeding, dysfunctional use such as the use of AVs as modes of transport to and from school, and driving on public roads without protecting or removing protruding and sharp components. For infrastructure, the focus is on road design and separation of AVs from other motor vehicles. Lessons to be learned follow from

  12. Skeletal muscle mechanics: questions, problems and possible solutions.

    PubMed

    Herzog, Walter

    2017-09-16

    Skeletal muscle mechanics have been studied ever since people have shown an interest in human movement. However, our understanding of muscle contraction and muscle mechanical properties has changed fundamentally with the discovery of the sliding filament theory in 1954 and associated cross-bridge theory in 1957. Nevertheless, experimental evidence suggests that our knowledge of the mechanisms of contraction is far from complete, and muscle properties and muscle function in human movement remain largely unknown.In this manuscript, I am trying to identify some of the crucial challenges we are faced with in muscle mechanics, offer possible solutions to questions, and identify problems that might be worthwhile exploring in the future. Since it is impossible to tackle all (worthwhile) problems in a single manuscript, I identified three problems that are controversial, important, and close to my heart. They may be identified as follows: (i) mechanisms of muscle contraction, (ii) in vivo whole muscle mechanics and properties, and (iii) force-sharing among synergistic muscles. These topics are fundamental to our understanding of human movement and movement control, and they contain a series of unknowns and challenges to be explored in the future.It is my hope that this paper may serve as an inspiration for some, may challenge current beliefs in selected areas, tackle important problems in the area of muscle mechanics, physiology and movement control, and may guide and focus some of the thinking of future muscle mechanics research.

  13. Problems Faced by Distance Learners in Using Web-Based Facilities

    ERIC Educational Resources Information Center

    Dharankar, Madhavi

    2012-01-01

    Countries like India are engaged in exploring appropriate ways of tackling the urgent problem of educating their large and growing populations in relatively little time and with limited resources. Against this background, achieving universal primary education is a major concern. If this Millennium Development Goal is to be achieved, the…

  14. Early Results of a Helmetless-Tackling Intervention to Decrease Head Impacts in Football Players

    PubMed Central

    Swartz, Erik E.; Broglio, Steven P.; Cook, Summer B.; Cantu, Robert C.; Ferrara, Michael S.; Guskiewicz, Kevin M.; Myers, Jay L.

    2015-01-01

    Objective To test a helmetless-tackling behavioral intervention for reducing head impacts in National Collegiate Athletic Association Division I football players. Design Randomized controlled clinical trial. Setting Football field. Patients or Other Participants Fifty collegiate football players (intervention = 25, control = 25). Intervention(s) The intervention group participated in a 5-minute tackling drill without their helmets and shoulder pads twice per week in the preseason and once per week through the season. During this time, the control group performed noncontact football skills. Main Outcome Measure(s) Frequency of head impacts was recorded by an impact sensor for each athlete-exposure (AE). Data were tested with a 2 × 3 (group and time) repeated-measures analysis of variance. Significant interactions and main effects (P < .05) were followed with t tests. Results Head impacts/AE decreased for the intervention group compared with the control group by the end of the season (9.99 ± 6.10 versus 13.84 ± 7.27, respectively). The intervention group had 30% fewer impacts/AE than the control group by season's end (9.99 ± 6.10 versus 14.32 ± 8.45, respectively). Conclusion A helmetless-tackling training intervention reduced head impacts in collegiate football players within 1 season. PMID:26651278

  15. Are Elementary School Teachers Prepared to Tackle Bullying? A Pilot Study

    ERIC Educational Resources Information Center

    Oldenburg, Beau; Bosman, Rie; Veenstra, René

    2016-01-01

    The aim of this pilot study was to investigate to what extent elementary school teachers were prepared to tackle bullying. Interview data from 22 Dutch elementary school teachers (M[subscript age]?=?43.3, 18 classrooms in eight schools) were combined with survey data from 373 students of these teachers (M age?=?10.7, grades 3-6, ages 8- to…

  16. Tackling Behaviour in Your Primary School: A Practical Handbook for Teachers

    ERIC Educational Resources Information Center

    Reid, Ken; Morgan, Nicola S.

    2012-01-01

    "Tackling Behaviour in the Primary School" provides ready-made advice and support for classroom professionals and can be used, read and adapted to suit the busy everyday lives of teachers working in primary schools today. This valuable text sets the scene for managing behaviour in the primary classroom in the context of the Children Act 2004…

  17. Tackling the child malnutrition problem: from what and why to how much and how.

    PubMed

    McLachlan, Milla

    2006-12-01

    There is strong economic evidence to invest in improving the economic status of young children, yet programs remain underresourced. Returns on investment in child nutrition in terms of improved health, better education outcomes and increased productivity are substantial, and cost estimates for effective programs are in the range of $2.8 to $5.3 billion. These amounts are modest when compared with total international development assistance or current spending on luxury goods in wealthy nations. New initiatives to redefine nutrition science and to apply innovative problem-solving technologies to the global nutrition problem suggest that steps are being taken to accelerate progress toward a malnutrition-free world.

  18. Tackling the Triple-Threat Genome of Miscanthus x giganteus (2010 JGI User Meeting)

    ScienceCinema

    Moose, Steve

    2018-02-05

    Steve Moose from the University of Illinois at Urbana-Champaign and the Energy Biosciences Institute on "Tackling the Triple-Threat Genome of Miscanthus x giganteus" on March 25, 2010 at the 5th Annual DOE JGI User Meeting.

  19. Tackling the Triple-Threat Genome of Miscanthus x giganteus (2010 JGI User Meeting)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moose, Steve

    2010-03-25

    Steve Moose from the University of Illinois at Urbana-Champaign and the Energy Biosciences Institute on "Tackling the Triple-Threat Genome of Miscanthus x giganteus" on March 25, 2010 at the 5th Annual DOE JGI User Meeting.

  20. The airport gate assignment problem: a survey.

    PubMed

    Bouras, Abdelghani; Ghaleb, Mageed A; Suryahatmaja, Umar S; Salem, Ahmed M

    2014-01-01

    The airport gate assignment problem (AGAP) is one of the most important problems operations managers face daily. Many researches have been done to solve this problem and tackle its complexity. The objective of the task is assigning each flight (aircraft) to an available gate while maximizing both conveniences to passengers and the operational efficiency of airport. This objective requires a solution that provides the ability to change and update the gate assignment data on a real time basis. In this paper, we survey the state of the art of these problems and the various methods to obtain the solution. Our survey covers both theoretical and real AGAP with the description of mathematical formulations and resolution methods such as exact algorithms, heuristic algorithms, and metaheuristic algorithms. We also provide a research trend that can inspire researchers about new problems in this area.

  1. The Airport Gate Assignment Problem: A Survey

    PubMed Central

    Ghaleb, Mageed A.; Salem, Ahmed M.

    2014-01-01

    The airport gate assignment problem (AGAP) is one of the most important problems operations managers face daily. Many researches have been done to solve this problem and tackle its complexity. The objective of the task is assigning each flight (aircraft) to an available gate while maximizing both conveniences to passengers and the operational efficiency of airport. This objective requires a solution that provides the ability to change and update the gate assignment data on a real time basis. In this paper, we survey the state of the art of these problems and the various methods to obtain the solution. Our survey covers both theoretical and real AGAP with the description of mathematical formulations and resolution methods such as exact algorithms, heuristic algorithms, and metaheuristic algorithms. We also provide a research trend that can inspire researchers about new problems in this area. PMID:25506074

  2. Return to Play Guidelines Cannot Solve the Football-Related Concussion Problem

    ERIC Educational Resources Information Center

    Johnson, L. Syd M.

    2012-01-01

    Background: High school football players are the single largest cohort of athletes playing tackle football, and account for the majority of sport-related concussions. Return to play guidelines (RTPs) have emerged as the preferred approach for addressing the problem of sport-related concussion in youth athletes. Methods: This article reviews…

  3. Modeling an integrated hospital management planning problem using integer optimization approach

    NASA Astrophysics Data System (ADS)

    Sitepu, Suryati; Mawengkang, Herman; Irvan

    2017-09-01

    Hospital is a very important institution to provide health care for people. It is not surprising that nowadays the people’s demands for hospital is increasing. However, due to the rising cost of healthcare services, hospitals need to consider efficiencies in order to overcome these two problems. This paper deals with an integrated strategy of staff capacity management and bed allocation planning to tackle these problems. Mathematically, the strategy can be modeled as an integer linear programming problem. We solve the model using a direct neighborhood search approach, based on the notion of superbasic variables.

  4. The growing problems of dental caries and obesity: an Australian perspective.

    PubMed

    Hopcraft, M S; Beaumont, S

    2016-10-07

    Preventable diet-related diseases such as dental caries and obesity are a growing global problem, causing a significant burden on public health systems. Although there has been good evidence for the links between sugar consumption and dental caries for many decades, we are now seeing stronger links implicating sugar in obesity. There is a growing worldwide movement to tackle these problems by targeting the consumption of sugar-sweetened beverages through a range of public policy measures.

  5. Replacing textbook problems with lab experiences

    NASA Astrophysics Data System (ADS)

    Register, Trevor

    2017-10-01

    End-of-the-chapter textbook problems are often the bread and butter of any traditional physics classroom. However, research strongly suggests that students be given the opportunity to apply their knowledge in multiple contexts as well as be provided with opportunities to do the process of science through laboratory experiences. Little correlation has been shown linking the number of textbook problems solved with conceptual understanding of topics in mechanics. Furthermore, textbook problems as the primary source of practice for students robs them of the joy and productive struggle of learning how to think like an experimental physicist. Methods such as Modeling Instruction tackle this problem head-on by starting each instructional unit with an inquiry-based lab aimed at establishing the important concepts and equations for the unit, and this article will discuss ideas and experiences for how to carry that philosophy throughout a unit.

  6. Tackling Social Cognition in Schizophrenia: A Randomized Feasibility Trial.

    PubMed

    Taylor, Rumina; Cella, Matteo; Csipke, Emese; Heriot-Maitland, Charles; Gibbs, Caroline; Wykes, Til

    2016-05-01

    Social cognition difficulties in schizophrenia are seen as a barrier to recovery. Intervention tackling problems in this domain have the potential to facilitate functioning and recovery. Social Cognition and Interaction Training (SCIT) is a manual-based psychological therapy designed to improve social functioning in schizophrenia. The aim of this study is to evaluate the feasibility and acceptability of a modified version of SCIT for inpatient forensic wards. The potential benefits of the intervention were also assessed. This study is a randomized single blind controlled design, with participants randomized to receive SCIT (N = 21) or treatment as usual (TAU; N = 15). SCIT consisted of 8-week therapy sessions twice per week. Participants were assessed at week 0 and one week after the intervention on measures of social cognition. Feasibility was assessed through group attendance and attrition. Participant acceptability and outcome was evaluated through post-group satisfaction and achievement of social goals. The intervention was well received by all participants and the majority reported their confidence improved. The SCIT group showed a significant improvement in facial affect recognition compared to TAU. Almost all participants agreed they had achieved their social goal as a result of the intervention. It is feasible to deliver SCIT in a forensic ward setting; however, some adaptation to the protocol may need to be considered in order to accommodate for the reduced social contact within forensic wards. Practice of social cognition skills in real life may be necessary to achieve benefits to theory of mind and attributional style.

  7. Towards an Evidence-Based Approach to Tackling Health Inequalities: The English Experience

    ERIC Educational Resources Information Center

    Killoran, Amanda; Kelly, Michael

    2004-01-01

    This short paper considers the development of an evidence-based approach to tackling health inequalities. Inequalities in health in England at the beginning of the 21st century have widened and are stark. Despite overall improvements in death rates, the growing gap between social groups means that now some parts of England have the same levels of…

  8. A Nationwide View of Undergraduates' Interest in Earth-related Careers and Motivation to Tackle Environmental Challenges

    NASA Astrophysics Data System (ADS)

    Kastens, K. A.; Mara, V.; Turrin, M.

    2016-12-01

    The InTeGrate Attitudinal Instrument (IAI) is an on-line survey that probes students' interest in Earth-related careers, their concern about environmental issues, and their motivation to tackle grand challenges of environmental sustainability and resource limitations. The survey has been taken by several thousand students, at the beginning and end of more than a hundred different undergraduate courses throughout the United States. All courses include some Earth/environmental content, but not all in are geoscience departments. Although results vary somewhat between subpopulations, taken in the aggregate the data paint a nation-wide picture of the state of undergraduates' environmental interests and concerns. Regardless of intended career path, respondents place a high value on working for an organization that is committed to environmentally sustainable practices. Respondents consistently indicate that developments such as global climate change, loss of biodiversity, and water resource limitations are a problem; however, these same students are much less consistent when it comes to engaging in personal behaviors that would help mitigate environmental problems, such as washing clothes in cold water or using recyclable bags when shopping. When asked what factors or sources of information influence their decisions to engage in the specified environmentally sustainable behaviors, the factor most often cited, by a wide margin, is "desire to save money," followed by "concern about pollution." A final open-ended question asked students if they can envision using what they have learned in this course to help society overcome problems of environmental degradation, natural resources limitations, or other environmental issues; if yes, how, and if no, why not. Strong majorities said yes. Among the minority who said no, commonly cited reasons include lack of empowerment (I'm only one person, the problems are too big); course was too general and didn't address solutions; and

  9. The patient-zero problem with noisy observations

    NASA Astrophysics Data System (ADS)

    Altarelli, Fabrizio; Braunstein, Alfredo; Dall'Asta, Luca; Ingrosso, Alessandro; Zecchina, Riccardo

    2014-10-01

    A belief propagation approach has been recently proposed for the patient-zero problem in SIR epidemics. The patient-zero problem consists of finding the initial source of an epidemic outbreak given observations at a later time. In this work, we study a more difficult but related inference problem, in which observations are noisy and there is confusion between observed states. In addition to studying the patient-zero problem, we also tackle the problem of completing and correcting the observations to possibly find undiscovered infected individuals and false test results. Moreover, we devise a set of equations, based on the variational expression of the Bethe free energy, to find the patient-zero along with maximum-likelihood epidemic parameters. We show, by means of simulated epidemics, that this method is able to infer details on the past history of an epidemic outbreak based solely on the topology of the contact network and a single snapshot of partial and noisy observations.

  10. Tackling pseudosymmetry problems in electron backscatter diffraction (EBSD) analyses of perovskite structures

    NASA Astrophysics Data System (ADS)

    Mariani, Elisabetta; Kaercher, Pamela; Mecklenburgh, Julian; Wheeler, John

    2016-04-01

    Perovskite minerals form an important mineral group that has applications in Earth science and emerging alternative energy technologies, however crystallographic quantification of these minerals with electron backscatter diffraction (EBSD) is not accurate due to pseudosymmetry problems. The silicate perovskite Bridgmanite, (Mg,Fe)SiO3, is understood to be the dominant phase in the Earth's lower mantle. Gaining insight into its physical and rheological properties is therefore vital to understand the dynamics of the Earth's deep interior. Rock deformation experiments on analogue perovskite phases, for example (Ca,Sr)TiO3, combined with quantitative microstructural analyses of the recovered samples by EBSD, yield datasets that can reveal what deformation mechanisms may dominate the flow of perovskite in the lower mantle. Additionally, perovskite structures have important technological applications as new, suitable cathodes for the operation of more efficient and environmentally-friendly solid oxide fuel cells (SOFC). In recent years they have also been recognised as a potential substitute for silicon in the next generation of photovoltaic cells for the construction of economic and energy efficient solar panels. EBSD has the potential to be a valuable tool for the study of crystal orientations achieved in perovskite substrates as crystal alignment has a direct control on the properties of these materials. However, perovskite structures currently present us with challenges during the automated indexing of Kikuchi bands in electron backscatter diffraction patterns (EBSPs). Such challenges are represented by the pseudosymmetric character of perovskites, where atoms are subtly displaced (0.005 nm to 0.05 nm) from their higher symmetry positions. In orthorhombic Pbnm perovskites, for example, pseudosymmetry may be evaluated from the c/a unit cell parameter ratio, which is very close to 1. Two main types of distortions from the higher symmetry structure are recognised: a

  11. Relationship between Principals Administrative Strategies and Student Disciplinary Problems in Secondary School, Bayelsa State

    ERIC Educational Resources Information Center

    Omemu, Felix

    2017-01-01

    This study examined the relationship between administrative strategy by principals and their effectiveness in tackling disciplinary problems. Three research questions were asked and one hypothesis was raised and tested at 0.05 level of significance. Ninety-five randomly selected principals from Bayelsa State constitute the sample. The instrument…

  12. Abortion as Fatherhood Lost: Problems and Reforms.

    ERIC Educational Resources Information Center

    Shostak, Arthur B.

    1979-01-01

    Reports on emotions of males when a near-fatherhood experience ends in a legal abortion. A sizeable minority of males find their abortion experience more frustrating, trying, and emotionally costly than public and academic neglect of this subject would suggest. Options are suggested to help males deal with abortion's aspects. (Author)

  13. Evaluating Behavioral Skills Training to Teach Safe Tackling Skills to Youth Football Players

    ERIC Educational Resources Information Center

    Tai, Sharayah S. M.; Miltenberger, Raymond G.

    2017-01-01

    With concussion rates on the rise for football players, there is a need for further research to increase skills and decrease injuries. Behavioral skills training is effective in teaching a wide variety of skills but has yet to be studied in the sports setting. We evaluated behavioral skills training to teach safer tackling techniques to six…

  14. Tackling the x-ray cargo inspection challenge using machine learning

    NASA Astrophysics Data System (ADS)

    Jaccard, Nicolas; Rogers, Thomas W.; Morton, Edward J.; Griffin, Lewis D.

    2016-05-01

    The current infrastructure for non-intrusive inspection of cargo containers cannot accommodate exploding com-merce volumes and increasingly stringent regulations. There is a pressing need to develop methods to automate parts of the inspection workflow, enabling expert operators to focus on a manageable number of high-risk images. To tackle this challenge, we developed a modular framework for automated X-ray cargo image inspection. Employing state-of-the-art machine learning approaches, including deep learning, we demonstrate high performance for empty container verification and specific threat detection. This work constitutes a significant step towards the partial automation of X-ray cargo image inspection.

  15. A multilevel probabilistic beam search algorithm for the shortest common supersequence problem.

    PubMed

    Gallardo, José E

    2012-01-01

    The shortest common supersequence problem is a classical problem with many applications in different fields such as planning, Artificial Intelligence and especially in Bioinformatics. Due to its NP-hardness, we can not expect to efficiently solve this problem using conventional exact techniques. This paper presents a heuristic to tackle this problem based on the use at different levels of a probabilistic variant of a classical heuristic known as Beam Search. The proposed algorithm is empirically analysed and compared to current approaches in the literature. Experiments show that it provides better quality solutions in a reasonable time for medium and large instances of the problem. For very large instances, our heuristic also provides better solutions, but required execution times may increase considerably.

  16. Creativity in Unique Problem-Solving in Mathematics and Its Influence on Motivation for Learning

    ERIC Educational Resources Information Center

    Bishara, Saied

    2016-01-01

    This research study investigates the ability of students to tackle the solving of unique mathematical problems in the domain of numerical series, verbal and formal, and its influence on the motivation of junior high students with learning disabilities in the Arab sector. Two instruments were used to collect the data: mathematical series were…

  17. Introduction: Unsolved Problems on Noise

    NASA Astrophysics Data System (ADS)

    Oriols, X.; Ciliberto, S.

    2016-05-01

    This paper is an introduction to the special issue of the 7th Int. Conf. on Unsolved Problems on Noise (UPoN) that took place at Casa Convalescència in Barcelona (Spain) in July 2015. The aim of the UPoN conferences is to provide a forum for researchers working on different fields of noise, fluctuations and variability, where they present their scientific problems which resist solutions. The papers of this Special Issue reflect the interdisciplinary topics (physics, biology, circuits, financial markets, psychology, technology, etc) presented at the UPoN conference. Noise is not only a hindrance to signal detection, but it is indeed a valuable source of information (not present in the signal) that help us to get a deeper understanding on how Nature works. This special issue of the 7th International Conference on Unsolved Problems on Noise (UPoN) is dedicated to Laszlo Kish in the occasion of his 60th birthday. He organized the first edition of these UPoN conferences in Szeged (Hungary) in 1996. Many of us have greatly benefited from his ‘volcanic imagination in tackling new problems from unconventional points of views’.

  18. Are health care provider organizations ready to tackle diagnostic error? A survey of Leapfrog-participating hospitals.

    PubMed

    Newman-Toker, David E; Austin, J Matthew; Derk, Jordan; Danforth, Melissa; Graber, Mark L

    2017-06-27

    A 2015 National Academy of Medicine report on improving diagnosis in health care made recommendations for direct action by hospitals and health systems. Little is known about how health care provider organizations are addressing diagnostic safety/quality. This study is an anonymous online survey of safety professionals from US hospitals and health systems in July-August 2016. The survey was sent to those attending a Leapfrog Group webinar on misdiagnosis (n=188). The instrument was focused on knowledge, attitudes, and capability to address diagnostic errors at the institutional level. Overall, 61 (32%) responded, including community hospitals (42%), integrated health networks (25%), and academic centers (21%). Awareness was high, but commitment and capability were low (31% of leaders understand the problem; 28% have sufficient safety resources; and 25% have made diagnosis a top institutional safety priority). Ongoing efforts to improve diagnostic safety were sparse and mostly included root cause analysis and peer review feedback around diagnostic errors. The top three barriers to addressing diagnostic error were lack of awareness of the problem, lack of measures of diagnostic accuracy and error, and lack of feedback on diagnostic performance. The top two tools viewed as critically important for locally tackling the problem were routine feedback on diagnostic performance and culture change to emphasize diagnostic safety. Although hospitals and health systems appear to be aware of diagnostic errors as a major safety imperative, most organizations (even those that appear to be making a strong commitment to patient safety) are not yet doing much to improve diagnosis. Going forward, efforts to activate health care organizations will be essential to improving diagnostic safety.

  19. Tackling the Problem of Repurposing Web Content

    ERIC Educational Resources Information Center

    Gerber, Nathan; Merker, Lance

    2008-01-01

    Like many institutions across the country, Utah Valley State College (UVSC) found itself struggling to keep its website current. In the spring of 2003, the UVSC's IT department began looking at alternatives that would simplify and streamline the process of updating the university's web pages. Specifically, they wanted a straightforward way to…

  20. Tackle-related injury rates and nature of injuries in South African Youth Week tournament rugby union players (under-13 to under-18): an observational cohort study.

    PubMed

    Burger, Nicholas; Lambert, Mike I; Viljoen, Wayne; Brown, James C; Readhead, Clint; Hendricks, Sharief

    2014-08-12

    The tackle situation is most often associated with the high injury rates in rugby union. Tackle injury epidemiology in rugby union has previously been focused on senior cohorts but less is known about younger cohorts. The aim of this study was to report on the nature and rates of tackle-related injuries in South African youth rugby union players representing their provinces at national tournaments. Observational cohort study. Four South African Youth Week tournaments (under-13 Craven Week, under-16 Grant Khomo Week, under-18 Academy Week, under-18 Craven Week). Injury data were collected from 3652 youth rugby union players (population at risk) in 2011 and 2012. Tackle-related injury severity ('time-loss' and 'medical attention'), type and location, injury rate per 1000 h (including 95% CIs). Injury rate ratios (IRR) were calculated and modelled using a Poisson regression. A χ(2) analysis was used to detect linear trends between injuries and increasing match quarters. The 2012 under-13 Craven Week had a significantly greater 'time-loss' injury rate when compared with the 2012 under-18 Academy Week (IRR=4.43; 95% CI 2.13 to 9.21, p<0.05) and under-18 Craven Week (IRR=3.52; 95% CI 1.54 to 8.00, p<0.05). The Poisson regression also revealed a higher probability of 'overall' ('time-loss' and 'medical attention' combined) and 'time-loss' tackle-related injuries occurring at the under-13 Craven Week. The proportion of 'overall' and 'time-loss' injuries increased significantly with each quarter of the match when all four tournaments were combined (p<0.05). There was a difference in the tackle-related injury rate between the under-13 tournament and the two under-18 tournaments, and the tackle-related injury rate was higher in the final quarter of matches. Ongoing injury surveillance is required to better interpret these findings. Injury prevention strategies targeting the tackle may only be effective once the rate and nature of injuries have been accurately determined

  1. Tackle-related injury rates and nature of injuries in South African Youth Week tournament rugby union players (under-13 to under-18): an observational cohort study

    PubMed Central

    Burger, Nicholas; Lambert, Mike I; Viljoen, Wayne; Brown, James C; Readhead, Clint; Hendricks, Sharief

    2014-01-01

    Objectives The tackle situation is most often associated with the high injury rates in rugby union. Tackle injury epidemiology in rugby union has previously been focused on senior cohorts but less is known about younger cohorts. The aim of this study was to report on the nature and rates of tackle-related injuries in South African youth rugby union players representing their provinces at national tournaments. Design Observational cohort study. Setting Four South African Youth Week tournaments (under-13 Craven Week, under-16 Grant Khomo Week, under-18 Academy Week, under-18 Craven Week). Participants Injury data were collected from 3652 youth rugby union players (population at risk) in 2011 and 2012. Outcome measures Tackle-related injury severity (‘time-loss’ and ‘medical attention’), type and location, injury rate per 1000 h (including 95% CIs). Injury rate ratios (IRR) were calculated and modelled using a Poisson regression. A χ2 analysis was used to detect linear trends between injuries and increasing match quarters. Results The 2012 under-13 Craven Week had a significantly greater ‘time-loss’ injury rate when compared with the 2012 under-18 Academy Week (IRR=4.43; 95% CI 2.13 to 9.21, p<0.05) and under-18 Craven Week (IRR=3.52; 95% CI 1.54 to 8.00, p<0.05). The Poisson regression also revealed a higher probability of ‘overall’ (‘time-loss’ and ‘medical attention’ combined) and ‘time-loss’ tackle-related injuries occurring at the under-13 Craven Week. The proportion of ‘overall’ and ‘time-loss’ injuries increased significantly with each quarter of the match when all four tournaments were combined (p<0.05). Conclusions There was a difference in the tackle-related injury rate between the under-13 tournament and the two under-18 tournaments, and the tackle-related injury rate was higher in the final quarter of matches. Ongoing injury surveillance is required to better interpret these findings. Injury prevention strategies

  2. The hospital microbiome project: meeting report for the UK science and innovation network UK-USA workshop ‘beating the superbugs: hospital microbiome studies for tackling antimicrobial resistance’, October 14th 2013

    PubMed Central

    2014-01-01

    The UK Science and Innovation Network UK-USA workshop ‘Beating the Superbugs: Hospital Microbiome Studies for tackling Antimicrobial Resistance’ was held on October 14th 2013 at the UK Department of Health, London. The workshop was designed to promote US-UK collaboration on hospital microbiome studies to add a new facet to our collective understanding of antimicrobial resistance. The assembled researchers debated the importance of the hospital microbial community in transmission of disease and as a reservoir for antimicrobial resistance genes, and discussed methodologies, hypotheses, and priorities. A number of complementary approaches were explored, although the importance of the built environment microbiome in disease transmission was not universally accepted. Current whole genome epidemiological methods are being pioneered in the UK and the benefits of moving to community analysis are not necessarily obvious to the pioneers; however, rapid progress in other areas of microbiology suggest to some researchers that hospital microbiome studies will be exceptionally fruitful even in the short term. Collaborative studies will recombine different strengths to tackle the international problems of antimicrobial resistance and hospital and healthcare associated infections.

  3. Black Holes, Information Loss and the Measurement Problem

    NASA Astrophysics Data System (ADS)

    Okon, Elias; Sudarsky, Daniel

    2017-01-01

    The information loss paradox is often presented as an unavoidable consequence of well-established physics. However, in order for a genuine paradox to ensue, not-trivial assumptions about, e.g., quantum effects on spacetime, are necessary. In this work we will be explicit about these additional, speculative assumptions required. We will also sketch a map of the available routes to tackle the issue, highlighting the, often overlooked, commitments demanded of each alternative. Finally, we will display the strong link between black holes, the issue of information loss and the measurement problem.

  4. Tackling the malaria problem in the South-East Asia Region: need for a change in policy?

    PubMed

    Bharati, Kaushik; Ganguly, N K

    2013-01-01

    Malaria is largely neglected in the South-East Asia Region (SEAR), although it has the highest number of people susceptible to the disease. Malaria in the SEAR exhibits special epidemiological characteristics such as "forest malaria" and malaria due to migration across international borders. The Greater Mekong Subregion (GMS) has been a focal-point for the emergence of drug resistant malaria. With the recent emergence of artemisinin resistance, coupled with the limited availability of insecticides, malaria control efforts in the SEAR face a steep challenge. Indirect man-made factors such as climate change, as well as direct man-made factors such as the circulation of counterfeit drugs have added to the problem. Increased monitoring, surveillance, pharmacovigilance as well as cross-border collaboration are required to address these problems. Regional networking and data-sharing will keep all stakeholders updated about the status of various malaria control programmes in the SEAR. Cutting-edge technologies such as GIS/GPS (geographical information system/global positioning system) systems and mobile phones can provide information in "real-time". A holistic and sustained approach to malaria control by integrated vector management (IVM) is suggested, in which all the stakeholder countries work collaboratively as a consortium. This approach will address the malaria problem in a collective manner so that malaria control can be sustained over time.

  5. Tackling the malaria problem in the South-East Asia Region: Need for a change in policy?

    PubMed Central

    Bharati, Kaushik; Ganguly, N. K.

    2013-01-01

    Malaria is largely neglected in the South-East Asia Region (SEAR), although it has the highest number of people susceptible to the disease. Malaria in the SEAR exhibits special epidemiological characteristics such as “forest malaria” and malaria due to migration across international borders. The Greater Mekong Subregion (GMS) has been a focal-point for the emergence of drug resistant malaria. With the recent emergence of artemisinin resistance, coupled with the limited availability of insecticides, malaria control efforts in the SEAR face a steep challenge. Indirect man-made factors such as climate change, as well as direct man-made factors such as the circulation of counterfeit drugs have added to the problem. Increased monitoring, surveillance, pharmacovigilance as well as cross-border collaboration are required to address these problems. Regional networking and data-sharing will keep all stakeholders updated about the status of various malaria control programmes in the SEAR. Cutting-edge technologies such as GIS/GPS (geographical information system/global positioning system) systems and mobile phones can provide information in “real-time”. A holistic and sustained approach to malaria control by integrated vector management (IVM) is suggested, in which all the stakeholder countries work collaboratively as a consortium. This approach will address the malaria problem in a collective manner so that malaria control can be sustained over time. PMID:23481050

  6. Application of tabu search to deterministic and stochastic optimization problems

    NASA Astrophysics Data System (ADS)

    Gurtuna, Ozgur

    During the past two decades, advances in computer science and operations research have resulted in many new optimization methods for tackling complex decision-making problems. One such method, tabu search, forms the basis of this thesis. Tabu search is a very versatile optimization heuristic that can be used for solving many different types of optimization problems. Another research area, real options, has also gained considerable momentum during the last two decades. Real options analysis is emerging as a robust and powerful method for tackling decision-making problems under uncertainty. Although the theoretical foundations of real options are well-established and significant progress has been made in the theory side, applications are lagging behind. A strong emphasis on practical applications and a multidisciplinary approach form the basic rationale of this thesis. The fundamental concepts and ideas behind tabu search and real options are investigated in order to provide a concise overview of the theory supporting both of these two fields. This theoretical overview feeds into the design and development of algorithms that are used to solve three different problems. The first problem examined is a deterministic one: finding the optimal servicing tours that minimize energy and/or duration of missions for servicing satellites around Earth's orbit. Due to the nature of the space environment, this problem is modeled as a time-dependent, moving-target optimization problem. Two solution methods are developed: an exhaustive method for smaller problem instances, and a method based on tabu search for larger ones. The second and third problems are related to decision-making under uncertainty. In the second problem, tabu search and real options are investigated together within the context of a stochastic optimization problem: option valuation. By merging tabu search and Monte Carlo simulation, a new method for studying options, Tabu Search Monte Carlo (TSMC) method, is

  7. Evidence in support of the call to ban the tackle and harmful contact in school rugby: a response to World Rugby.

    PubMed

    Pollock, Allyson M; White, Adam John; Kirkwood, Graham

    2017-08-01

    In a paper published in BJSM (June 2016), World Rugby employees Ross Tucker and Martin Raftery and a third coauthor Evert Verhagen took issue with the recent call to ban tackling in school rugby in the UK and Ireland. That call (to ban tackling) was supported by a systematic review published in BJSM Tucker et al claim that: (1) the mechanisms and risk factors for injury along with the incidence and severity of injury in youth rugby union have not been thoroughly identified or understood; (2) rugby players are at no greater risk of injury than other sports people, (3) this is particularly the case for children under 15 years and (4) removing the opportunity to learn the tackle from school pupils might increase rates of injuries. They conclude that a ban 'may be unnecessary and may also lead to unintended consequences such as an increase in the risk of injury later in participation.' Here we aim to rebut the case by Tucker et al We share new research that extends the findings of our original systematic review and meta-analysis. A cautionary approach requires the removal of the tackle from school rugby as the quickest and most effective method of reducing high injury rates in youth rugby, a public health priority. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  8. Fixing America's College Attainment Problems: It's about More than Affordability. Critical Considerations for Any New Federal-State Partnership

    ERIC Educational Resources Information Center

    Santos, Jose Luis; Haycock, Kati

    2016-01-01

    In response to mounting concerns about the cost of college, lawmakers have proposed major new partnerships between the federal government and states to tackle college affordability. The Education Trust maintains that any new federal-state proposal aimed at making college more affordable must also simultaneously address completion problems by…

  9. On solving three-dimensional open-dimension rectangular packing problems

    NASA Astrophysics Data System (ADS)

    Junqueira, Leonardo; Morabito, Reinaldo

    2017-05-01

    In this article, a recently proposed three-dimensional open-dimension rectangular packing problem is considered, in which the objective is to find a minimal volume rectangular container that packs a set of rectangular boxes. The literature has tackled small-sized instances of this problem by means of optimization solvers, position-free mixed-integer programming (MIP) formulations and piecewise linearization approaches. In this study, the problem is alternatively addressed by means of grid-based position MIP formulations, whereas still considering optimization solvers and the same piecewise linearization techniques. A comparison of the computational performance of both models is then presented, when tested with benchmark problem instances and with new instances, and it is shown that the grid-based position MIP formulation can be competitive, depending on the characteristics of the instances. The grid-based position MIP formulation is also embedded with real-world practical constraints, such as cargo stability, and results are additionally presented.

  10. Improving Psychosexual Knowledge in Adolescents with Autism Spectrum Disorder: Pilot of the Tackling Teenage Training Program

    ERIC Educational Resources Information Center

    Dekker, Linda P.; van der Vegt, Esther J.; Visser, Kirsten; Tick, Nouchka; Boudesteijn, Frieda; Verhulst, Frank C.; Maras, Athanasios; Greaves-Lord, Kirstin

    2015-01-01

    Previous studies have shown that psychosexual functioning in adolescents with autism spectrum disorder (ASD) is hampered and emphasize the need for a specialized training program tailored to their needs. Therefore, an individual training program was developed; the Tackling Teenage Training (TTT) program. The current pilot study systematically…

  11. Ecological literacy and beyond: Problem-based learning for future professionals.

    PubMed

    Lewinsohn, Thomas M; Attayde, José Luiz; Fonseca, Carlos Roberto; Ganade, Gislene; Jorge, Leonardo Ré; Kollmann, Johannes; Overbeck, Gerhard E; Prado, Paulo Inácio; Pillar, Valério D; Popp, Daniela; da Rocha, Pedro L B; Silva, Wesley Rodrigues; Spiekermann, Annette; Weisser, Wolfgang W

    2015-03-01

    Ecological science contributes to solving a broad range of environmental problems. However, lack of ecological literacy in practice often limits application of this knowledge. In this paper, we highlight a critical but often overlooked demand on ecological literacy: to enable professionals of various careers to apply scientific knowledge when faced with environmental problems. Current university courses on ecology often fail to persuade students that ecological science provides important tools for environmental problem solving. We propose problem-based learning to improve the understanding of ecological science and its usefulness for real-world environmental issues that professionals in careers as diverse as engineering, public health, architecture, social sciences, or management will address. Courses should set clear learning objectives for cognitive skills they expect students to acquire. Thus, professionals in different fields will be enabled to improve environmental decision-making processes and to participate effectively in multidisciplinary work groups charged with tackling environmental issues.

  12. Impact of the New Mental Health Services on Rates of Suicide and Hospitalisations by Attempted Suicide, Psychiatric Problems, and Alcohol Problems in Brazil.

    PubMed

    Machado, Daiane B; Alves, Flávia Jôse; Rasella, Davide; Rodrigues, Laura; Araya, Ricardo

    2018-05-01

    A sizeable proportion of all suicides have mental health issues in the background. The association between access to mental health care in the community and decreased suicide rates is inconsistent in the literature. Brazil undertook a major psychiatric reform strengthening psychiatric community-based care. To evaluate the impact of the new Brazilian community mental health care units (CAPS-Psychosocial-Community-Centres) on municipal rates of suicide, and hospitalisations by attempted suicide, psychiatric and alcohol problems. We performed robust multivariable negative binomial regression models with fixed effect for panel data from all 5507 Brazilian municipalities. Suicide and hospitalization rates were calculated by sex and standardised by age for each municipality and year from 2008 to 2012. The main variable of interest was municipal CAPS coverage. CAPS municipal coverage was associated with lower suicide rates but this was not statistically significant (RR: 0.981; 95% CI 0.952-1.011). However, increased CAPS coverage was associated with lower hospitalizations for attempted suicide (RR: 0.887; 95% CI 0.841-0.935), psychiatric (RR: 0.841; 95% CI 0.821-0.862), and alcohol problems (RR: 0.882; 95% CI 0.860-0.904). Our results suggest that access to community mental health services seems to reduce hospitalisations due to attempted suicide, psychiatric and alcohol problems but not suicidal rates. Therefore, increased investments in community mental health services in low-middle-income countries might decrease costs associated with potentially avoidable hospitalizations.

  13. The coral reefs optimization algorithm: a novel metaheuristic for efficiently solving optimization problems.

    PubMed

    Salcedo-Sanz, S; Del Ser, J; Landa-Torres, I; Gil-López, S; Portilla-Figueras, J A

    2014-01-01

    This paper presents a novel bioinspired algorithm to tackle complex optimization problems: the coral reefs optimization (CRO) algorithm. The CRO algorithm artificially simulates a coral reef, where different corals (namely, solutions to the optimization problem considered) grow and reproduce in coral colonies, fighting by choking out other corals for space in the reef. This fight for space, along with the specific characteristics of the corals' reproduction, produces a robust metaheuristic algorithm shown to be powerful for solving hard optimization problems. In this research the CRO algorithm is tested in several continuous and discrete benchmark problems, as well as in practical application scenarios (i.e., optimum mobile network deployment and off-shore wind farm design). The obtained results confirm the excellent performance of the proposed algorithm and open line of research for further application of the algorithm to real-world problems.

  14. The Coral Reefs Optimization Algorithm: A Novel Metaheuristic for Efficiently Solving Optimization Problems

    PubMed Central

    Salcedo-Sanz, S.; Del Ser, J.; Landa-Torres, I.; Gil-López, S.; Portilla-Figueras, J. A.

    2014-01-01

    This paper presents a novel bioinspired algorithm to tackle complex optimization problems: the coral reefs optimization (CRO) algorithm. The CRO algorithm artificially simulates a coral reef, where different corals (namely, solutions to the optimization problem considered) grow and reproduce in coral colonies, fighting by choking out other corals for space in the reef. This fight for space, along with the specific characteristics of the corals' reproduction, produces a robust metaheuristic algorithm shown to be powerful for solving hard optimization problems. In this research the CRO algorithm is tested in several continuous and discrete benchmark problems, as well as in practical application scenarios (i.e., optimum mobile network deployment and off-shore wind farm design). The obtained results confirm the excellent performance of the proposed algorithm and open line of research for further application of the algorithm to real-world problems. PMID:25147860

  15. Towards overcoming the Monte Carlo sign problem with tensor networks

    NASA Astrophysics Data System (ADS)

    Bañuls, Mari Carmen; Cichy, Krzysztof; Ignacio Cirac, J.; Jansen, Karl; Kühn, Stefan; Saito, Hana

    2017-03-01

    The study of lattice gauge theories with Monte Carlo simulations is hindered by the infamous sign problem that appears under certain circumstances, in particular at non-zero chemical potential. So far, there is no universal method to overcome this problem. However, recent years brought a new class of non-perturbative Hamiltonian techniques named tensor networks, where the sign problem is absent. In previous work, we have demonstrated that this approach, in particular matrix product states in 1+1 dimensions, can be used to perform precise calculations in a lattice gauge theory, the massless and massive Schwinger model. We have computed the mass spectrum of this theory, its thermal properties and real-time dynamics. In this work, we review these results and we extend our calculations to the case of two flavours and non-zero chemical potential. We are able to reliably reproduce known analytical results for this model, thus demonstrating that tensor networks can tackle the sign problem of a lattice gauge theory at finite density.

  16. Genetic Algorithm for Traveling Salesman Problem with Modified Cycle Crossover Operator

    PubMed Central

    Mohamd Shoukry, Alaa; Gani, Showkat

    2017-01-01

    Genetic algorithms are evolutionary techniques used for optimization purposes according to survival of the fittest idea. These methods do not ensure optimal solutions; however, they give good approximation usually in time. The genetic algorithms are useful for NP-hard problems, especially the traveling salesman problem. The genetic algorithm depends on selection criteria, crossover, and mutation operators. To tackle the traveling salesman problem using genetic algorithms, there are various representations such as binary, path, adjacency, ordinal, and matrix representations. In this article, we propose a new crossover operator for traveling salesman problem to minimize the total distance. This approach has been linked with path representation, which is the most natural way to represent a legal tour. Computational results are also reported with some traditional path representation methods like partially mapped and order crossovers along with new cycle crossover operator for some benchmark TSPLIB instances and found improvements. PMID:29209364

  17. Genetic Algorithm for Traveling Salesman Problem with Modified Cycle Crossover Operator.

    PubMed

    Hussain, Abid; Muhammad, Yousaf Shad; Nauman Sajid, M; Hussain, Ijaz; Mohamd Shoukry, Alaa; Gani, Showkat

    2017-01-01

    Genetic algorithms are evolutionary techniques used for optimization purposes according to survival of the fittest idea. These methods do not ensure optimal solutions; however, they give good approximation usually in time. The genetic algorithms are useful for NP-hard problems, especially the traveling salesman problem. The genetic algorithm depends on selection criteria, crossover, and mutation operators. To tackle the traveling salesman problem using genetic algorithms, there are various representations such as binary, path, adjacency, ordinal, and matrix representations. In this article, we propose a new crossover operator for traveling salesman problem to minimize the total distance. This approach has been linked with path representation, which is the most natural way to represent a legal tour. Computational results are also reported with some traditional path representation methods like partially mapped and order crossovers along with new cycle crossover operator for some benchmark TSPLIB instances and found improvements.

  18. Can Smoking Cessation Services Be Better Targeted to Tackle Health Inequalities? Evidence from a Cross-Sectional Study

    ERIC Educational Resources Information Center

    Blackman, Tim

    2008-01-01

    Objective: To investigate how smoking cessation services could be more effectively targeted to tackle socioeconomic inequalities in health. Design: Secondary analysis of data from a household interview survey undertaken for Middlesbrough Council in north east England using the technique of Qualitative Comparative Analysis. Setting: Home-based…

  19. Industry Responsibilities in Tackling Direct-to-Consumer Marketing of Unproven Stem Cell Treatments.

    PubMed

    Master, Z; Fu, W; Paciulli, D; Sipp, D

    2017-08-01

    The direct-to-consumer marketing of unproven stem cell interventions (SCIs) is a serious public health concern. Regulations and education have had modest impact, indicating that different actors must play a role to stop this unfettered market. We consider the role of the biotech industry in tackling unproven SCIs. Grounded in the concept of corporate social responsibility, we argue that biotech companies should screen consumers to ensure that products and services are being used appropriately and educate employees about unproven SCIs. © 2017 ASCPT.

  20. Approaches to Interactive Video Anchors in Problem-based Science Learning

    NASA Astrophysics Data System (ADS)

    Kumar, David Devraj

    2010-02-01

    This paper is an invited adaptation of the IEEE Education Society Distinguished Lecture Approaches to Interactive Video Anchors in Problem-Based Science Learning. Interactive video anchors have a cognitive theory base, and they help to enlarge the context of learning with information-rich real-world situations. Carefully selected movie clips and custom-developed regular videos and virtual simulations have been successfully used as anchors in problem-based science learning. Examples discussed include a range of situations such as Indiana Jones tackling a trap, a teenager misrepresenting lead for gold, an agriculture inspection at the US border, counterintuitive events, analyzing a river ecosystem for pollution, and finding the cause of illness in a nineteenth century river city. Suggestions for teachers are provided.

  1. Tackling unsafe abortion in Mauritius.

    PubMed

    Nyong'o, D; Oodit, G

    1996-01-01

    Despite a contraceptive prevalence rate of 75% Mauritius has a high incidence of unsafe abortions because of unprotected intercourse experienced by many young women in a rapidly industrializing environment. The Mauritius Family Planning Association (MFPA) tackled the issue of unsafe abortion in 1993. Abortion is illegal in the country, and the Catholic Church also strongly opposes modern family planning methods, thus the use of withdrawal and/or calendar methods have been increasing. The MFPA organized an advocacy symposium in 1993 on unsafe abortion with the result of revealing the pressure the Church was exerting relative to abortion and contraceptives. The advocacy campaign of the MFPA consists of having abortion legalized on health grounds and improving family planning services, especially for young unmarried women and men. The full support of the media was secured on the abortion issue: articles appeared, meetings were attended by the press, and public relations support was also received from them. The MFPA worked closely with parliamentarians. A motion was tabled in 1994 in the National Assembly which called for legalization of abortion on health grounds, but the Church squelched its debate. In March 1994 MFPA hosted the IPPF African Regional Conference on Unsafe Abortion in Mauritius with the participation of over 100 representatives from 20 countries, and subsequently a second motion was tabled without parliamentary debate. The deliberations were covered by the media and the Ministry of Women's Rights recognized abortion as an urgent issue as outlined in a white paper prepared for the Fourth World Conference on Women held in Beijing in 1995. The campaign changed the policy climate favorably making the public more conscious of unsafe abortion. The Ministry of Health decided to collect more data and the newly elected government seems to be more open about this issue.

  2. An Island Grouping Genetic Algorithm for Fuzzy Partitioning Problems

    PubMed Central

    Salcedo-Sanz, S.; Del Ser, J.; Geem, Z. W.

    2014-01-01

    This paper presents a novel fuzzy clustering technique based on grouping genetic algorithms (GGAs), which are a class of evolutionary algorithms especially modified to tackle grouping problems. Our approach hinges on a GGA devised for fuzzy clustering by means of a novel encoding of individuals (containing elements and clusters sections), a new fitness function (a superior modification of the Davies Bouldin index), specially tailored crossover and mutation operators, and the use of a scheme based on a local search and a parallelization process, inspired from an island-based model of evolution. The overall performance of our approach has been assessed over a number of synthetic and real fuzzy clustering problems with different objective functions and distance measures, from which it is concluded that the proposed approach shows excellent performance in all cases. PMID:24977235

  3. Tackling maize fusariosis: in search of Fusarium graminearum biosuppressors.

    PubMed

    Adeniji, Adetomiwa Ayodele; Babalola, Olubukola Oluranti

    2018-06-22

    This review presents biocontrol agents employed to alleviate the deleterious effect of the pathogen Fusarium graminearum on maize. The control of this mycotoxigenic phytopathogen remains elusive despite the elaborate research conducted on its detection, identification, and molecular fingerprinting. This could be attributed to the fact that in vitro and greenhouse biocontrol studies on F. graminearum have exceeded the number of field studies done. Furthermore, along with the variances seen among these F. graminearum suppressing biocontrol strains, it is also clear that the majority of research done to tackle F. graminearum outbreaks was on wheat and barley cultivars. Most fusariosis management related to maize targeted other members of Fusarium such as Fusarium verticillioides, with biocontrol strains from the genera Bacillus and Pseudomonas being used frequently in the experiments. We highlight relevant current techniques needed to identify an effective biofungicide for maize fusariosis and recommend alternative approaches to reduce the scarcity of data for indigenous maize field trials.

  4. The politics of partnerships: a study of police and housing collaboration to tackle anti-social behaviour on Australian public housing estates.

    PubMed

    Jacobs, Keith

    2010-01-01

    This paper draws on the findings from a research project on partnership arrangements between the police and housing departments on three Australian public housing estates to tackle problems associated with illicit drug activity and anti-social behaviour (ASB). The analysis focused on the setting up of the partnerships and the interactions that followed from these institutional arrangements. The assumption that informs the paper is that when studying partnerships there is a need for a more critically framed analysis. The temptation to posit "a successful model" of what partnership entails and then to judge practices in relation to this model is considerable, but it inevitably falls into the trap of constructing a narrative of partnership success or failure in terms of individual agency (that is, the degree of commitment from individuals). The analysis undertaken in this paper has therefore sought to fathom a more complex set of organizational processes. Rather than confine the discussion to issues of success and failure, the study foregrounds the subjective accounts of individuals who work within partnership and the constraints they encounter. The paper therefore makes explicit the cultural tensions within and across agencies, contestation as to the extent of the policy "problem," and the divergent perspectives on the appropriate modes of intervention.

  5. Alexithymia and psychosocial problems among Italian preadolescents. A latent class analysis approach.

    PubMed

    Mannarini, Stefania; Balottin, Laura; Toldo, Irene; Gatta, Michela

    2016-10-01

    The study, conducted on Italian preadolscents aged 11 to 13 belonging to the general population, aims to investigate the relationship between the emotional functioning, namely, alexithymia, and the risk of developing behavioral and emotional problems measured using the Strength and Difficulty Questionnaire. The latent class analysis approach allowed to identify two latent variables, accounting for the internalizing (emotional symptoms and difficulties in emotional awareness) and for the externalizing problems (conduct problems and hyperactivity, problematic relationships with peers, poor prosocial behaviors and externally oriented thinking). The two latent variables featured two latent classes: the difficulty in dealing with problems and the strength to face problems that was representative of most of the healthy participants with specific gender differences. Along with the analysis of psychopathological behaviors, the study of resilience and strengths can prove to be a key step in order to develop valuable preventive approaches to tackle psychiatric disorders. © 2016 Scandinavian Psychological Associations and John Wiley & Sons Ltd.

  6. Caught in the (Education) Act: Tackling Michael Gove's Education Revolution. Report on 19th November 2011 Conference

    ERIC Educational Resources Information Center

    FORUM: for promoting 3-19 comprehensive education, 2012

    2012-01-01

    A number of significant campaigning organisations and education trades unions--the Anti-Academies Alliance, CASE, Comprehensive Future, Forum, ISCG and the Socialist Educational Association, along with ASCL, ATL, NASUWT and NUT--staged a conference in London on 19 November 2011, with the title 'Caught in the (Education) Act: tackling Michael…

  7. The 1998 flood in Bangladesh: is different targeting needed during emergencies and recovery to tackle malnutrition?

    PubMed

    Hossain, S M; Kolsteren, Patrick

    2003-06-01

    Bangladesh suffered the century's worst flood during July-October 1998 and appealed for assistance. To provide information for appropriate interventions to tackle nutritional problems, a rapid assessment survey was conducted to look at the nutritional situation, problems encountered by the community, their coping mechanisms and rehabilitation priorities in six rural areas. The survey was repeated after four months to measure the outcome of activities during the flood and the necessity for future assistance. There were 3,048 children measured in both surveys (1,597 and 1,451). The sample of most interest was a sub-group of 180 children present in two previous independent surveys. The analysis found that while moving from the crisis period to post-flood phase there was evidence of a 'crossover phenomenon' in the recovery pattern of nutritional status. Sixty-eight per cent of the children who were malnourished (WHZ < -2SD) during the crisis period (18 per cent) recovered enough to cross the cut-off point and became normal after four months. Another 8 per cent of children (9 per cent of all normal) who were normal during the crisis period, after four months had deteriorated to be malnourished. Thus, despite there being a shift in the overall distribution of nutritional status, there has been another shift that reduced the net effect. Subsequent episodes of diarrhoea, access to food and loan burden had also influenced the recovery pattern of the children's nutritional status as evident from the statistically significant associations. These findings raise questions about targeting acute malnutrition during emergencies, and using the same criteria during both the crisis and rehabilitation phases.

  8. Tackling student neurophobia in neurosciences block with team-based learning.

    PubMed

    Anwar, Khurshid; Shaikh, Abdul A; Sajid, Muhammad R; Cahusac, Peter; Alarifi, Norah A; Al Shedoukhy, Ahlam

    2015-01-01

    Traditionally, neurosciences is perceived as a difficult course in undergraduate medical education with literature suggesting use of the term "Neurophobia" (fear of neurology among medical students). Instructional strategies employed for the teaching of neurosciences in undergraduate curricula traditionally include a combination of lectures, demonstrations, practical classes, problem-based learning and clinico-pathological conferences. Recently, team-based learning (TBL), a student-centered instructional strategy, has increasingly been regarded by many undergraduate medical courses as an effective method to assist student learning. In this study, 156 students of year-three neuroscience block were divided into seven male and seven female groups, comprising 11-12 students in each group. TBL was introduced during the 6 weeks of this block, and a total of eight TBL sessions were conducted during this duration. We evaluated the effect of TBL on student learning and correlated it with the student's performance in summative assessment. Moreover, the students' perceptions regarding the process of TBL was assessed by online survey. We found that students who attended TBL sessions performed better in the summative examinations as compared to those who did not. Furthermore, students performed better in team activities compared to individual testing, with male students performing better with a more favorable impact on their grades in the summative examination. There was an increase in the number of students achieving higher grades (grade B and above) in this block when compared to the previous block (51.7% vs. 25%). Moreover, the number of students at risk for lower grades (Grade B- and below) decreased in this block when compared to the previous block (30.6% vs. 55%). Students generally elicited a favorable response regarding the TBL process, as well as expressed satisfaction with the content covered and felt that such activities led to improvement in communication and

  9. Soilborne Diseases of the Nursery Industry: USDA-ARS and OSU Team Up to Tackle this Pernicious Problem

    USDA-ARS?s Scientific Manuscript database

    Soilborne diseases are a serious problem affecting many crop plants of the ornamental nursery industry. Recently, the Horticultural Crops Research Laboratory (USDA-ARS) and Oregon State University received funding from the Floriculture and Nursery Research Initiative via the Horticultural Research I...

  10. Adolescence Behaviour Problems: How to Tackle or Prevent?

    ERIC Educational Resources Information Center

    Kumar, V. Jurist Lionial

    2013-01-01

    Adolescence is a transitional stage of physical and mental human development that occurs between child hood and adulthood. Adolescent period starts with puberty. The period during which the capability for sexual reproduction is attained; it is marked by changes in both primary and secondary sexual characteristics and is dated from menarche in…

  11. Redesigning primary care to tackle the global epidemic of noncommunicable disease.

    PubMed

    Kruk, Margaret E; Nigenda, Gustavo; Knaul, Felicia M

    2015-03-01

    Noncommunicable diseases (NCDs) have become the major contributors to death and disability worldwide. Nearly 80% of the deaths in 2010 occurred in low- and middle-income countries, which have experienced rapid population aging, urbanization, rise in smoking, and changes in diet and activity. Yet the health systems of low- and middle-income countries, historically oriented to infectious disease and often severely underfunded, are poorly prepared for the challenge of caring for people with cardiovascular disease, diabetes, cancer, and chronic respiratory disease. We have discussed how primary care can be redesigned to tackle the challenge of NCDs in resource-constrained countries. We suggest that four changes will be required: integration of services, innovative service delivery, a focus on patients and communities, and adoption of new technologies for communication.

  12. How we tackled the problem of assessing humanities, social and behavioural sciences in medical education.

    PubMed

    Goodwin, Dawn; Machin, Laura

    2016-01-01

    Assessment serves as an important motivation for learning. However, multiple choice and short answer question formats are often considered unsatisfactory for assessment of medical humanities, and the social and behavioural sciences. Little consensus exists as to what might constitute 'best' assessment practice. What we did: We designed an assessment format closely aligned to the curricular approach of problem-based learning which allows for greater assessment of students' understanding, depth of knowledge and interpretation, rather than recall of rote learning. The educational impact of scenario-based assessment has been profound. Students reported changing their approach to PBL, independent learning and exam preparation by taking a less reductionist, more interpretative approach to the topics studied.

  13. Does a SLAP lesion affect shoulder muscle recruitment as measured by EMG activity during a rugby tackle?

    PubMed Central

    2010-01-01

    Background The study objective was to assess the influence of a SLAP lesion on onset of EMG activity in shoulder muscles during a front on rugby football tackle within professional rugby players. Methods Mixed cross-sectional study evaluating between and within group differences in EMG onset times. Testing was carried out within the physiotherapy department of a university sports medicine clinic. The test group consisted of 7 players with clinically diagnosed SLAP lesions, later verified on arthroscopy. The reference group consisted of 15 uninjured and full time professional rugby players from within the same playing squad. Controlled tackles were performed against a tackle dummy. Onset of EMG activity was assessed from surface EMG of Pectorialis Major, Biceps Brachii, Latissimus Dorsi, Serratus Anterior and Infraspinatus muscles relative to time of impact. Analysis of differences in activation timing between muscles and limbs (injured versus non-injured side and non injured side versus matched reference group). Results Serratus Anterior was activated prior to all other muscles in all (P = 0.001-0.03) subjects. In the SLAP injured shoulder Biceps was activated later than in the non-injured side. Onset times of all muscles of the non-injured shoulder in the injured player were consistently earlier compared with the reference group. Whereas, within the injured shoulder, all muscle activation timings were later than in the reference group. Conclusions This study shows that in shoulders with a SLAP lesion there is a trend towards delay in activation time of Biceps and other muscles with the exception of an associated earlier onset of activation of Serratus anterior, possibly due to a coping strategy to protect glenohumeral stability and thoraco-scapular stability. This trend was not statistically significant in all cases PMID:20184752

  14. The Strength of the Strongest Ties in Collaborative Problem Solving

    NASA Astrophysics Data System (ADS)

    de Montjoye, Yves-Alexandre; Stopczynski, Arkadiusz; Shmueli, Erez; Pentland, Alex; Lehmann, Sune

    2014-06-01

    Complex problem solving in science, engineering, and business has become a highly collaborative endeavor. Teams of scientists or engineers collaborate on projects using their social networks to gather new ideas and feedback. Here we bridge the literature on team performance and information networks by studying teams' problem solving abilities as a function of both their within-team networks and their members' extended networks. We show that, while an assigned team's performance is strongly correlated with its networks of expressive and instrumental ties, only the strongest ties in both networks have an effect on performance. Both networks of strong ties explain more of the variance than other factors, such as measured or self-evaluated technical competencies, or the personalities of the team members. In fact, the inclusion of the network of strong ties renders these factors non-significant in the statistical analysis. Our results have consequences for the organization of teams of scientists, engineers, and other knowledge workers tackling today's most complex problems.

  15. The strength of the strongest ties in collaborative problem solving.

    PubMed

    de Montjoye, Yves-Alexandre; Stopczynski, Arkadiusz; Shmueli, Erez; Pentland, Alex; Lehmann, Sune

    2014-06-20

    Complex problem solving in science, engineering, and business has become a highly collaborative endeavor. Teams of scientists or engineers collaborate on projects using their social networks to gather new ideas and feedback. Here we bridge the literature on team performance and information networks by studying teams' problem solving abilities as a function of both their within-team networks and their members' extended networks. We show that, while an assigned team's performance is strongly correlated with its networks of expressive and instrumental ties, only the strongest ties in both networks have an effect on performance. Both networks of strong ties explain more of the variance than other factors, such as measured or self-evaluated technical competencies, or the personalities of the team members. In fact, the inclusion of the network of strong ties renders these factors non-significant in the statistical analysis. Our results have consequences for the organization of teams of scientists, engineers, and other knowledge workers tackling today's most complex problems.

  16. Accurate ω-ψ Spectral Solution of the Singular Driven Cavity Problem

    NASA Astrophysics Data System (ADS)

    Auteri, F.; Quartapelle, L.; Vigevano, L.

    2002-08-01

    This article provides accurate spectral solutions of the driven cavity problem, calculated in the vorticity-stream function representation without smoothing the corner singularities—a prima facie impossible task. As in a recent benchmark spectral calculation by primitive variables of Botella and Peyret, closed-form contributions of the singular solution for both zero and finite Reynolds numbers are subtracted from the unknown of the problem tackled here numerically in biharmonic form. The method employed is based on a split approach to the vorticity and stream function equations, a Galerkin-Legendre approximation of the problem for the perturbation, and an evaluation of the nonlinear terms by Gauss-Legendre numerical integration. Results computed for Re=0, 100, and 1000 compare well with the benchmark steady solutions provided by the aforementioned collocation-Chebyshev projection method. The validity of the proposed singularity subtraction scheme for computing time-dependent solutions is also established.

  17. Generalist solutions to complex problems: generating practice-based evidence - the example of managing multi-morbidity

    PubMed Central

    2013-01-01

    Background A growing proportion of people are living with long term conditions. The majority have more than one. Dealing with multi-morbidity is a complex problem for health systems: for those designing and implementing healthcare as well as for those providing the evidence informing practice. Yet the concept of multi-morbidity (the presence of >2 diseases) is a product of the design of health care systems which define health care need on the basis of disease status. So does the solution lie in an alternative model of healthcare? Discussion Strengthening generalist practice has been proposed as part of the solution to tackling multi-morbidity. Generalism is a professional philosophy of practice, deeply known to many practitioners, and described as expertise in whole person medicine. But generalism lacks the evidence base needed by policy makers and planners to support service redesign. The challenge is to fill this practice-research gap in order to critically explore if and when generalist care offers a robust alternative to management of this complex problem. We need practice-based evidence to fill this gap. By recognising generalist practice as a ‘complex intervention’ (intervening in a complex system), we outline an approach to evaluate impact using action-research principles. We highlight the implications for those who both commission and undertake research in order to tackle this problem. Summary Answers to the complex problem of multi-morbidity won’t come from doing more of the same. We need to change systems of care, and so the systems for generating evidence to support that care. This paper contributes to that work through outlining a process for generating practice-based evidence of generalist solutions to the complex problem of person-centred care for people with multi-morbidity. PMID:23919296

  18. Generalist solutions to complex problems: generating practice-based evidence--the example of managing multi-morbidity.

    PubMed

    Reeve, Joanne; Blakeman, Tom; Freeman, George K; Green, Larry A; James, Paul A; Lucassen, Peter; Martin, Carmel M; Sturmberg, Joachim P; van Weel, Chris

    2013-08-07

    A growing proportion of people are living with long term conditions. The majority have more than one. Dealing with multi-morbidity is a complex problem for health systems: for those designing and implementing healthcare as well as for those providing the evidence informing practice. Yet the concept of multi-morbidity (the presence of >2 diseases) is a product of the design of health care systems which define health care need on the basis of disease status. So does the solution lie in an alternative model of healthcare? Strengthening generalist practice has been proposed as part of the solution to tackling multi-morbidity. Generalism is a professional philosophy of practice, deeply known to many practitioners, and described as expertise in whole person medicine. But generalism lacks the evidence base needed by policy makers and planners to support service redesign. The challenge is to fill this practice-research gap in order to critically explore if and when generalist care offers a robust alternative to management of this complex problem. We need practice-based evidence to fill this gap. By recognising generalist practice as a 'complex intervention' (intervening in a complex system), we outline an approach to evaluate impact using action-research principles. We highlight the implications for those who both commission and undertake research in order to tackle this problem. Answers to the complex problem of multi-morbidity won't come from doing more of the same. We need to change systems of care, and so the systems for generating evidence to support that care. This paper contributes to that work through outlining a process for generating practice-based evidence of generalist solutions to the complex problem of person-centred care for people with multi-morbidity.

  19. Transgressive Local Act: Tackling Domestic Violence with Forum and Popular Theatre in "Sisterhood Bound as Yuan Ze Flowers"

    ERIC Educational Resources Information Center

    Wang, Wan-Jung

    2010-01-01

    This paper examines a community theatre project in Kaohsiung County, Taiwan that aimed to tackle domestic violence through a collaboration between local community female elders and the facilitator. The paper investigates how an outside facilitator could unfix the assumed community identities which tend to exclude outsiders or sub-groups, in this…

  20. Redesigning Primary Care to Tackle the Global Epidemic of Noncommunicable Disease

    PubMed Central

    Nigenda, Gustavo; Knaul, Felicia M.

    2015-01-01

    Noncommunicable diseases (NCDs) have become the major contributors to death and disability worldwide. Nearly 80% of the deaths in 2010 occurred in low- and middle-income countries, which have experienced rapid population aging, urbanization, rise in smoking, and changes in diet and activity. Yet the health systems of low- and middle-income countries, historically oriented to infectious disease and often severely underfunded, are poorly prepared for the challenge of caring for people with cardiovascular disease, diabetes, cancer, and chronic respiratory disease. We have discussed how primary care can be redesigned to tackle the challenge of NCDs in resource-constrained countries. We suggest that four changes will be required: integration of services, innovative service delivery, a focus on patients and communities, and adoption of new technologies for communication. PMID:25602898

  1. An efficient heuristic method for dynamic portfolio selection problem under transaction costs and uncertain conditions

    NASA Astrophysics Data System (ADS)

    Najafi, Amir Abbas; Pourahmadi, Zahra

    2016-04-01

    Selecting the optimal combination of assets in a portfolio is one of the most important decisions in investment management. As investment is a long term concept, looking into a portfolio optimization problem just in a single period may cause loss of some opportunities that could be exploited in a long term view. Hence, it is tried to extend the problem from single to multi-period model. We include trading costs and uncertain conditions to this model which made it more realistic and complex. Hence, we propose an efficient heuristic method to tackle this problem. The efficiency of the method is examined and compared with the results of the rolling single-period optimization and the buy and hold method which shows the superiority of the proposed method.

  2. Higgs-portal assisted Higgs inflation with a sizeable tensor-to-scalar ratio

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, Jinsu; Ko, Pyungwon; Park, Wan-Il, E-mail: kimjinsu@kias.re.kr, E-mail: pko@kias.re.kr, E-mail: Wanil.Park@uv.es

    We show that the Higgs portal interactions involving extra dark Higgs field can save generically the original Higgs inflation of the standard model (SM) from the problem of a deep non-SM vacuum in the SM Higgs potential. Specifically, we show that such interactions disconnect the top quark pole mass from inflationary observables and allow multi-dimensional parameter space to save the Higgs inflation, thanks to the additional parameters (the dark Higgs boson mass m {sub φ}, the mixing angle α between the SM Higgs H and dark Higgs Φ, and the mixed quartic coupling) affecting RG-running of the Higgs quartic coupling.more » The effect of Higgs portal interactions may lead to a larger tensor-to-scalar ratio, 0.08 ∼< r ∼< 0.1, by adjusting relevant parameters in wide ranges of α and m {sub φ}, some region of which can be probed at future colliders. Performing a numerical analysis we find an allowed region of parameters, matching the latest Planck data.« less

  3. Impact of a United Kingdom-wide campaign to tackle antimicrobial resistance on self-reported knowledge and behaviour change.

    PubMed

    Chaintarli, Katerina; Ingle, Suzanne M; Bhattacharya, Alex; Ashiru-Oredope, Diane; Oliver, Isabel; Gobin, Maya

    2016-05-12

    As part of the 2014 European Antibiotic Awareness Day plans, a new campaign called Antibiotic Guardian (AG) was launched in the United Kingdom, including an online pledge system to increase commitment from healthcare professionals and members of the public to reduce antimicrobial resistance (AMR). The aim of this evaluation was to determine the impact of the campaign on self-reported knowledge and behaviour around AMR. An online survey was sent to 9016 Antibiotic Guardians (AGs) to assess changes in self-reported knowledge and behaviour (outcomes) following the campaign. Logistic regression models, adjusted for variables including age, sex and pledge group (pledging as member of public or as healthcare professional), were used to estimate associations between outcomes and AG characteristics. 2478 AGs responded to the survey (27.5 % response rate) of whom 1696 (68.4 %) pledged as healthcare professionals and 782 (31.6 %) as members of public (similar proportions to the total number of AGs). 96.3 % of all AGs who responded had prior knowledge of AMR. 73.5 % of participants were female and participants were most commonly between 45 and 54 years old. Two thirds (63.4 %) of participants reported always acting according to their pledge. Members of the public were more likely to act in line with their pledge than professionals (Odds Ratio (OR) =3.60, 95 % Confidence Interval (CI): 2.88-4.51). Approximately half of participants (44.5 %) (both healthcare professionals and members of public) reported that they acquired more knowledge about AMR post-campaign. People that were confused about AMR prior to the campaign acquired more knowledge after the campaign (OR = 3.10, 95 % CI: 1.36-7.09). More participants reported a sense of personal responsibility towards tackling AMR post-campaign, increasing from 58.3 % of participants pre-campaign to 70.5 % post-campaign. This study demonstrated that the campaign increased commitment to tackling AMR in both healthcare

  4. Expansion of the 'Antibiotic Guardian' one health behavioural campaign across Europe to tackle antibiotic resistance: pilot phase and analysis of AMR knowledge.

    PubMed

    Newitt, Sophie; Anthierens, Sibyl; Coenen, Samuel; Lo Fo Wong, Danilo; Salvi, Cristiana; Puleston, Richard; Ashiru-Oredope, Diane

    2018-06-01

    Antimicrobial resistance (AMR) is a major public health threat. The UK Antibiotic Guardian (AG) behavioural change campaign developed to tackle AMR was expanded across Europe through translation into Russian, Dutch and French. Demographics and knowledge of AGs were analyzed between 01 November 2016 and 31 December 2016. A total of 367 pledges were received with the majority from the public and health care professionals. The pilot has significantly increased the proportion of pledges from Europe (excluding UK) (χ2 = 108.7, P < 0.001). AMR knowledge was greater in AGs (including the public) compared to the EU Eurobarometer survey. Further promotion across Europe is required to measure an impact on tackling AMR.

  5. Tackling NCD in LMIC: Achievements and Lessons Learned From the NHLBI-UnitedHealth Global Health Centers of Excellence Program.

    PubMed

    Engelgau, Michael M; Sampson, Uchechukwu K; Rabadan-Diehl, Cristina; Smith, Richard; Miranda, Jaime; Bloomfield, Gerald S; Belis, Deshiree; Narayan, K M Venkat

    2016-03-01

    Effectively tackling the growing noncommunicable disease (NCD) burden in low- and middle-income countries (LMIC) is a major challenge. To address research needs in this setting for NCDs, in 2009, National Heart, Lung, and Blood Institute (NHLBI) and UnitedHealth Group (UHG) engaged in a public-private partnership that supported a network of 11 LMIC-based research centers and created the NHLBI-UnitedHealth Global Health Centers of Excellence (COE) Program. The Program's overall goal was to contribute to reducing the cardiovascular and lung disease burdens by catalyzing in-country research institutions to develop a global network of biomedical research centers. Key elements of the Program included team science and collaborative approaches, developing research and training platforms for future investigators, and creating a data commons. This Program embraced a strategic approach for tackling NCDs in LMICs and will provide capacity for locally driven research efforts that can identify and address priority health issues in specific countries' settings. Published by Elsevier B.V.

  6. Metaheuristic optimisation methods for approximate solving of singular boundary value problems

    NASA Astrophysics Data System (ADS)

    Sadollah, Ali; Yadav, Neha; Gao, Kaizhou; Su, Rong

    2017-07-01

    This paper presents a novel approximation technique based on metaheuristics and weighted residual function (WRF) for tackling singular boundary value problems (BVPs) arising in engineering and science. With the aid of certain fundamental concepts of mathematics, Fourier series expansion, and metaheuristic optimisation algorithms, singular BVPs can be approximated as an optimisation problem with boundary conditions as constraints. The target is to minimise the WRF (i.e. error function) constructed in approximation of BVPs. The scheme involves generational distance metric for quality evaluation of the approximate solutions against exact solutions (i.e. error evaluator metric). Four test problems including two linear and two non-linear singular BVPs are considered in this paper to check the efficiency and accuracy of the proposed algorithm. The optimisation task is performed using three different optimisers including the particle swarm optimisation, the water cycle algorithm, and the harmony search algorithm. Optimisation results obtained show that the suggested technique can be successfully applied for approximate solving of singular BVPs.

  7. Development of common neural representations for distinct numerical problems

    PubMed Central

    Chang, Ting-Ting; Rosenberg-Lee, Miriam; Metcalfe, Arron W. S.; Chen, Tianwen; Menon, Vinod

    2015-01-01

    How the brain develops representations for abstract cognitive problems is a major unaddressed question in neuroscience. Here we tackle this fundamental question using arithmetic problem solving, a cognitive domain important for the development of mathematical reasoning. We first examined whether adults demonstrate common neural representations for addition and subtraction problems, two complementary arithmetic operations that manipulate the same quantities. We then examined how the common neural representations for the two problem types change with development. Whole-brain multivoxel representational similarity (MRS) analysis was conducted to examine common coding of addition and subtraction problems in children and adults. We found that adults exhibited significant levels of MRS between the two problem types, not only in the intra-parietal sulcus (IPS) region of the posterior parietal cortex (PPC), but also in ventral temporal-occipital, anterior temporal and dorsolateral prefrontal cortices. Relative to adults, children showed significantly reduced levels of MRS in these same regions. In contrast, no brain areas showed significantly greater MRS between problem types in children. Our findings provide novel evidence that the emergence of arithmetic problem solving skills from childhood to adulthood is characterized by maturation of common neural representations between distinct numerical operations, and involve distributed brain regions important for representing and manipulating numerical quantity. More broadly, our findings demonstrate that representational analysis provides a powerful approach for uncovering fundamental mechanisms by which children develop proficiencies that are a hallmark of human cognition. PMID:26160287

  8. Tackling student neurophobia in neurosciences block with team-based learning

    PubMed Central

    Anwar, Khurshid; Shaikh, Abdul A.; Sajid, Muhammad R.; Cahusac, Peter; Alarifi, Norah A.; Al Shedoukhy, Ahlam

    2015-01-01

    Introduction Traditionally, neurosciences is perceived as a difficult course in undergraduate medical education with literature suggesting use of the term “Neurophobia” (fear of neurology among medical students). Instructional strategies employed for the teaching of neurosciences in undergraduate curricula traditionally include a combination of lectures, demonstrations, practical classes, problem-based learning and clinico-pathological conferences. Recently, team-based learning (TBL), a student-centered instructional strategy, has increasingly been regarded by many undergraduate medical courses as an effective method to assist student learning. Methods In this study, 156 students of year-three neuroscience block were divided into seven male and seven female groups, comprising 11–12 students in each group. TBL was introduced during the 6 weeks of this block, and a total of eight TBL sessions were conducted during this duration. We evaluated the effect of TBL on student learning and correlated it with the student's performance in summative assessment. Moreover, the students’ perceptions regarding the process of TBL was assessed by online survey. Results We found that students who attended TBL sessions performed better in the summative examinations as compared to those who did not. Furthermore, students performed better in team activities compared to individual testing, with male students performing better with a more favorable impact on their grades in the summative examination. There was an increase in the number of students achieving higher grades (grade B and above) in this block when compared to the previous block (51.7% vs. 25%). Moreover, the number of students at risk for lower grades (Grade B- and below) decreased in this block when compared to the previous block (30.6% vs. 55%). Students generally elicited a favorable response regarding the TBL process, as well as expressed satisfaction with the content covered and felt that such activities led to

  9. Tackling Critical Catalytic Residues in Helicobacter pylori l-Asparaginase

    PubMed Central

    Maggi, Maristella; Chiarelli, Laurent R; Valentini, Giovanna; Scotti, Claudia

    2015-01-01

    Bacterial asparaginases (amidohydrolases, EC 3.5.1.1) are important enzymes in cancer therapy, especially for Acute Lymphoblastic Leukemia. They are tetrameric enzymes able to catalyze the deamination of l-ASN and, to a variable extent, of l-GLN, on which leukemia cells are dependent for survival. In contrast to other known l-asparaginases, Helicobacter pylori CCUG 17874 type II enzyme (HpASNase) is cooperative and has a low affinity towards l-GLN. In this study, some critical amino acids forming the active site of HpASNase (T16, T95 and E289) have been tackled by rational engineering in the attempt to better define their role in catalysis and to achieve a deeper understanding of the peculiar cooperative behavior of this enzyme. Mutations T16E, T95D and T95H led to a complete loss of enzymatic activity. Mutation E289A dramatically reduced the catalytic activity of the enzyme, but increased its thermostability. Interestingly, E289 belongs to a loop that is very variable in l-asparaginases from the structure, sequence and length point of view, and which could be a main determinant of their different catalytic features. PMID:25826146

  10. Tackling Critical Catalytic Residues in Helicobacter pylori L-Asparaginase.

    PubMed

    Maggi, Maristella; Chiarelli, Laurent R; Valentini, Giovanna; Scotti, Claudia

    2015-03-27

    Bacterial asparaginases (amidohydrolases, EC 3.5.1.1) are important enzymes in cancer therapy, especially for Acute Lymphoblastic Leukemia. They are tetrameric enzymes able to catalyze the deamination of L-ASN and, to a variable extent, of L-GLN, on which leukemia cells are dependent for survival. In contrast to other known L-asparaginases, Helicobacter pylori CCUG 17874 type II enzyme (HpASNase) is cooperative and has a low affinity towards L-GLN. In this study, some critical amino acids forming the active site of HpASNase (T16, T95 and E289) have been tackled by rational engineering in the attempt to better define their role in catalysis and to achieve a deeper understanding of the peculiar cooperative behavior of this enzyme. Mutations T16E, T95D and T95H led to a complete loss of enzymatic activity. Mutation E289A dramatically reduced the catalytic activity of the enzyme, but increased its thermostability. Interestingly, E289 belongs to a loop that is very variable in L-asparaginases from the structure, sequence and length point of view, and which could be a main determinant of their different catalytic features.

  11. Solving lot-sizing problem with quantity discount and transportation cost

    NASA Astrophysics Data System (ADS)

    Lee, Amy H. I.; Kang, He-Yau; Lai, Chun-Mei

    2013-04-01

    Owing to today's increasingly competitive market and ever-changing manufacturing environment, the inventory problem is becoming more complicated to solve. The incorporation of heuristics methods has become a new trend to tackle the complex problem in the past decade. This article considers a lot-sizing problem, and the objective is to minimise total costs, where the costs include ordering, holding, purchase and transportation costs, under the requirement that no inventory shortage is allowed in the system. We first formulate the lot-sizing problem as a mixed integer programming (MIP) model. Next, an efficient genetic algorithm (GA) model is constructed for solving large-scale lot-sizing problems. An illustrative example with two cases in a touch panel manufacturer is used to illustrate the practicality of these models, and a sensitivity analysis is applied to understand the impact of the changes in parameters to the outcomes. The results demonstrate that both the MIP model and the GA model are effective and relatively accurate tools for determining the replenishment for touch panel manufacturing for multi-periods with quantity discount and batch transportation. The contributions of this article are to construct an MIP model to obtain an optimal solution when the problem is not too complicated itself and to present a GA model to find a near-optimal solution efficiently when the problem is complicated.

  12. Tackling causes and costs of ED presentation for American football injuries: a population-level study.

    PubMed

    Smart, Blair J; Haring, R Sterling; Asemota, Anthony O; Scott, John W; Canner, Joseph K; Nejim, Besma J; George, Benjamin P; Alsulaim, Hatim; Kirsch, Thomas D; Schneider, Eric B

    2016-07-01

    American tackle football is the most popular high-energy impact sport in the United States, with approximately 9 million participants competing annually. Previous epidemiologic studies of football-related injuries have generally focused on specific geographic areas or pediatric age groups. Our study sought to examine patient characteristics and outcomes, including hospital charges, among athletes presenting for emergency department (ED) treatment of football-related injury across all age groups in a large nationally representative data set. Patients presenting for ED treatment of injuries sustained playing American tackle football (identified using International Classification of Diseases, Ninth Revision, Clinical Modification code E007.0) from 2010 to 2011 were studied in the Nationwide Emergency Department Sample. Patient-specific injuries were identified using the primary International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis code and categorized by type and anatomical region. Standard descriptive methods examined patient demographics, diagnosis categories, and ED and inpatient outcomes and charges. During the study period 397363 football players presented for ED treatment, 95.8% of whom were male. Sprains/strains (25.6%), limb fractures (20.7%), and head injuries (including traumatic brain injury; 17.5%) represented the most presenting injuries. Overall, 97.9% of patients underwent routine ED discharge with 1.1% admitted directly and fewer than 11 patients in the 2-year study period dying prior to discharge. The proportion of admitted patients who required surgical interventions was 15.7%, of which 89.9% were orthopedic, 4.7% neurologic, and 2.6% abdominal. Among individuals admitted to inpatient care, mean hospital length of stay was 2.4days (95% confidence interval, 2.2-2.6) and 95.6% underwent routine discharge home. The mean total charge for all patients was $1941 (95% confidence interval, $1890-$1992) with substantial

  13. Tackling Health Inequalities in the United Kingdom: The Progress and Pitfalls of Policy

    PubMed Central

    Exworthy, Mark; Blane, David; Marmot, Michael

    2003-01-01

    Goal Assess the progress and pitfalls of current United Kingdom (U.K.) policies to reduce health inequalities. Objectives (1) Describe the context enabling health inequalities to get onto the policy agenda in the United Kingdom. (2) Categorize and assess selected current U.K. policies that may affect health inequalities. (3) Apply the “policy windows” model to understand the issues faced in formulating and implementing such policies. (4) Examine the emerging policy challenges in the U.K. and elsewhere. Data Sources Official documents, secondary analyses, and interviews with policymakers. Study Design Qualitative, policy analysis. Data Collection 2001–2002. The methods were divided into two stages. The first identified policies which were connected with individual inquiry recommendations. The second involved case-studies of three policies areas which were thought to be crucial in tackling health inequalities. Both stages involved interviews with policy-makers and documentary analysis. Principal Findings (1) The current U.K. government stated a commitment to reducing health inequalities. (2) The government has begun to implement policies that address the wider determinants. (3) Some progress is evident but many indicators remain stubborn. (4) Difficulties remain in terms of coordinating policies across government and measuring progress. (5) The “policy windows” model explains the limited extent of progress and highlights current and possible future pitfalls. (6) The U.K.'s experience has lessons for other governments involved in tackling health inequalities. Conclusions Health inequalities are on the agenda of U.K. government policy and steps have been made to address them. There are some signs of progress but much remains to be done including overcoming some of the perverse incentives at the national level, improving joint working, ensuring appropriate measures of performance/progress, and improving monitoring arrangements. A conceptual policy model aids

  14. High School Football Players Use Their Helmets to Tackle Other Players Despite Knowing the Risks

    PubMed Central

    Kuriyama, Andrew M; Nakatsuka, Austin S

    2017-01-01

    There is greater attention to head-related injuries and concussions in American football. The helmet's structural safety and the way that football players use their helmets are important in preventing head injuries. Current strategies include penalizing players for high-risk behavior such as leading with their helmet or hitting an opposing player above the shoulder. Passive strategies include helmet modification to better protect the head of the players or to change the playing style of the players. Hawai‘i high school varsity football players were surveyed to determine how they use their helmets and how a new helmet design would affect their style of play. One hundred seventy-seven surveys were completed; 79% said that they used their helmet to hit an opposing player during a tackle and 46% said they made this contact intentionally. When asked about modifying helmets with a soft material on the outside, 48% said they thought putting a soft cover over a regular helmet would protect their head better. However, many participants said that putting a soft cover over their regular helmet was a bad idea for various reasons. Most young football players use their helmets to block or tackle despite being taught they would be penalized or potentially injured if they did so. By gaining a better understanding of why and how players use their helmets and how they would respond to new helmet designs, steps can be taken to reduce head injuries for all levels of play. PMID:28352493

  15. High School Football Players Use Their Helmets to Tackle Other Players Despite Knowing the Risks.

    PubMed

    Kuriyama, Andrew M; Nakatsuka, Austin S; Yamamoto, Loren G

    2017-03-01

    There is greater attention to head-related injuries and concussions in American football. The helmet's structural safety and the way that football players use their helmets are important in preventing head injuries. Current strategies include penalizing players for high-risk behavior such as leading with their helmet or hitting an opposing player above the shoulder. Passive strategies include helmet modification to better protect the head of the players or to change the playing style of the players. Hawai'i high school varsity football players were surveyed to determine how they use their helmets and how a new helmet design would affect their style of play. One hundred seventy-seven surveys were completed; 79% said that they used their helmet to hit an opposing player during a tackle and 46% said they made this contact intentionally. When asked about modifying helmets with a soft material on the outside, 48% said they thought putting a soft cover over a regular helmet would protect their head better. However, many participants said that putting a soft cover over their regular helmet was a bad idea for various reasons. Most young football players use their helmets to block or tackle despite being taught they would be penalized or potentially injured if they did so. By gaining a better understanding of why and how players use their helmets and how they would respond to new helmet designs, steps can be taken to reduce head injuries for all levels of play.

  16. Artificial immune algorithm for multi-depot vehicle scheduling problems

    NASA Astrophysics Data System (ADS)

    Wu, Zhongyi; Wang, Donggen; Xia, Linyuan; Chen, Xiaoling

    2008-10-01

    In the fast-developing logistics and supply chain management fields, one of the key problems in the decision support system is that how to arrange, for a lot of customers and suppliers, the supplier-to-customer assignment and produce a detailed supply schedule under a set of constraints. Solutions to the multi-depot vehicle scheduling problems (MDVRP) help in solving this problem in case of transportation applications. The objective of the MDVSP is to minimize the total distance covered by all vehicles, which can be considered as delivery costs or time consumption. The MDVSP is one of nondeterministic polynomial-time hard (NP-hard) problem which cannot be solved to optimality within polynomial bounded computational time. Many different approaches have been developed to tackle MDVSP, such as exact algorithm (EA), one-stage approach (OSA), two-phase heuristic method (TPHM), tabu search algorithm (TSA), genetic algorithm (GA) and hierarchical multiplex structure (HIMS). Most of the methods mentioned above are time consuming and have high risk to result in local optimum. In this paper, a new search algorithm is proposed to solve MDVSP based on Artificial Immune Systems (AIS), which are inspirited by vertebrate immune systems. The proposed AIS algorithm is tested with 30 customers and 6 vehicles located in 3 depots. Experimental results show that the artificial immune system algorithm is an effective and efficient method for solving MDVSP problems.

  17. Tackling racism as a "wicked" public health problem: Enabling allies in anti-racism praxis.

    PubMed

    Came, Heather; Griffith, Derek

    2018-02-01

    Racism is a "wicked" public health problem that fuels systemic health inequities between population groups in New Zealand, the United States and elsewhere. While literature has examined racism and its effects on health, the work describing how to intervene to address racism in public health is less developed. While the notion of raising awareness of racism through socio-political education is not new, given the way racism has morphed into new narratives in health institutional settings, it has become critical to support allies to make informing efforts to address racism as a fundamental cause of health inequities. In this paper, we make the case for anti-racism praxis as a tool to address inequities in public health, and focus on describing an anti-racism praxis framework to inform the training and support of allies. The limited work on anti-racism rarely articulates the unique challenges or needs of allies or targets of racism, but we seek to help fill that gap. Our anti-racism praxis for allies includes five core elements: reflexive relational praxis, structural power analysis, socio-political education, monitoring and evaluation and systems change approaches. We recognize that racism is a modifiable determinant of health and racial inequities can be eliminated with the necessary political will and a planned system change approach. Anti-racism praxis provides the tools to examine the interconnection and interdependence of cultural and institutional factors as a foundation for examining where and how to intervene to address racism. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Synthetic biology approaches to biological containment: pre-emptively tackling potential risks

    PubMed Central

    Krüger, Antje; Csibra, Eszter; Gianni, Edoardo

    2016-01-01

    Biocontainment comprises any strategy applied to ensure that harmful organisms are confined to controlled laboratory conditions and not allowed to escape into the environment. Genetically engineered microorganisms (GEMs), regardless of the nature of the modification and how it was established, have potential human or ecological impact if accidentally leaked or voluntarily released into a natural setting. Although all evidence to date is that GEMs are unable to compete in the environment, the power of synthetic biology to rewrite life requires a pre-emptive strategy to tackle possible unknown risks. Physical containment barriers have proven effective but a number of strategies have been developed to further strengthen biocontainment. Research on complex genetic circuits, lethal genes, alternative nucleic acids, genome recoding and synthetic auxotrophies aim to design more effective routes towards biocontainment. Here, we describe recent advances in synthetic biology that contribute to the ongoing efforts to develop new and improved genetic, semantic, metabolic and mechanistic plans for the containment of GEMs. PMID:27903826

  19. Synthetic biology approaches to biological containment: pre-emptively tackling potential risks.

    PubMed

    Torres, Leticia; Krüger, Antje; Csibra, Eszter; Gianni, Edoardo; Pinheiro, Vitor B

    2016-11-30

    Biocontainment comprises any strategy applied to ensure that harmful organisms are confined to controlled laboratory conditions and not allowed to escape into the environment. Genetically engineered microorganisms (GEMs), regardless of the nature of the modification and how it was established, have potential human or ecological impact if accidentally leaked or voluntarily released into a natural setting. Although all evidence to date is that GEMs are unable to compete in the environment, the power of synthetic biology to rewrite life requires a pre-emptive strategy to tackle possible unknown risks. Physical containment barriers have proven effective but a number of strategies have been developed to further strengthen biocontainment. Research on complex genetic circuits, lethal genes, alternative nucleic acids, genome recoding and synthetic auxotrophies aim to design more effective routes towards biocontainment. Here, we describe recent advances in synthetic biology that contribute to the ongoing efforts to develop new and improved genetic, semantic, metabolic and mechanistic plans for the containment of GEMs. © 2016 The Author(s).

  20. A Randomized Controlled Trial to Examine the Effects of the Tackling Teenage Psychosexual Training Program for Adolescents with Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    Visser, Kirsten; Greaves-Lord, Kirstin; Tick, Nouchka T.; Verhulst, Frank C.; Maras, Athanasios; van der Vegt, Esther J. M.

    2017-01-01

    Background: Previous research underscores the importance of psychosexual guidance for adolescents with autism spectrum disorder (ASD). Such guidance is provided in the Tackling Teenage Training (TTT) program, in which adolescents with ASD receive psycho-education and practice communicative skills regarding topics related to puberty, sexuality, and…

  1. Ant Colony Optimization With Local Search for Dynamic Traveling Salesman Problems.

    PubMed

    Mavrovouniotis, Michalis; Muller, Felipe M; Yang, Shengxiang

    2016-06-13

    For a dynamic traveling salesman problem (DTSP), the weights (or traveling times) between two cities (or nodes) may be subject to changes. Ant colony optimization (ACO) algorithms have proved to be powerful methods to tackle such problems due to their adaptation capabilities. It has been shown that the integration of local search operators can significantly improve the performance of ACO. In this paper, a memetic ACO algorithm, where a local search operator (called unstring and string) is integrated into ACO, is proposed to address DTSPs. The best solution from ACO is passed to the local search operator, which removes and inserts cities in such a way that improves the solution quality. The proposed memetic ACO algorithm is designed to address both symmetric and asymmetric DTSPs. The experimental results show the efficiency of the proposed memetic algorithm for addressing DTSPs in comparison with other state-of-the-art algorithms.

  2. Determining the number of fingers in the lifting Hele-Shaw problem

    NASA Astrophysics Data System (ADS)

    Miranda, Jose; Dias, Eduardo

    2013-11-01

    The lifting Hele-Shaw cell flow is a variation of the celebrated radial viscous fingering problem for which the upper cell plate is lifted uniformly at a specified rate. This procedure causes the formation of intricate interfacial patterns. Most theoretical studies determine the total number of emerging fingers by maximizing the linear growth rate, but this generates discrepancies between theory and experiments. In this work, we tackle the number of fingers selection problem in the lifting Hele-Shaw cell by employing the recently proposed maximum-amplitude criterion. Our linear stability analysis accounts for the action of capillary, viscous normal stresses, and wetting effects, as well as the cell confinement. The comparison of our results with very precise laboratory measurements for the total number of fingers shows a significantly improved agreement between theoretical predictions and experimental data. We thank CNPq (Brazilian Sponsor) for financial support.

  3. [Current problems in the use of probation with compulsory work].

    PubMed

    Salautdinov, S A

    1976-01-01

    In the framework of the Soviet law, probation accompanied by compulsory work represents an up-to-date measure of a criminal character that allows to rehabilitate a convicted offender without depriving him of his freedom. The Panfederal Institute for the study of the causes of criminal behaviour and for the formulation of measures for preventing it, has conducted a number of researches directed at clearing up some debated problems bearing on the implementation of the measures existing on the subject, and at collecting proposals of amendment. The present article deals with the assumptions and preconditions, of both an objective and subjective character, underlying the application of this juridical institute, and also tackles, by referring to some cases previously occurred, the problems posed by the various types of subjects. Special attention is devoted to the decision-making procedure followed by the tribunals in applying the said measures, and to the various elements on which it is to be based.

  4. A Large-Scale Study of Fingerprint Matching Systems for Sensor Interoperability Problem

    PubMed Central

    Hussain, Muhammad; AboAlSamh, Hatim; AlZuair, Mansour

    2018-01-01

    The fingerprint is a commonly used biometric modality that is widely employed for authentication by law enforcement agencies and commercial applications. The designs of existing fingerprint matching methods are based on the hypothesis that the same sensor is used to capture fingerprints during enrollment and verification. Advances in fingerprint sensor technology have raised the question about the usability of current methods when different sensors are employed for enrollment and verification; this is a fingerprint sensor interoperability problem. To provide insight into this problem and assess the status of state-of-the-art matching methods to tackle this problem, we first analyze the characteristics of fingerprints captured with different sensors, which makes cross-sensor matching a challenging problem. We demonstrate the importance of fingerprint enhancement methods for cross-sensor matching. Finally, we conduct a comparative study of state-of-the-art fingerprint recognition methods and provide insight into their abilities to address this problem. We performed experiments using a public database (FingerPass) that contains nine datasets captured with different sensors. We analyzed the effects of different sensors and found that cross-sensor matching performance deteriorates when different sensors are used for enrollment and verification. In view of our analysis, we propose future research directions for this problem. PMID:29597286

  5. A Large-Scale Study of Fingerprint Matching Systems for Sensor Interoperability Problem.

    PubMed

    AlShehri, Helala; Hussain, Muhammad; AboAlSamh, Hatim; AlZuair, Mansour

    2018-03-28

    The fingerprint is a commonly used biometric modality that is widely employed for authentication by law enforcement agencies and commercial applications. The designs of existing fingerprint matching methods are based on the hypothesis that the same sensor is used to capture fingerprints during enrollment and verification. Advances in fingerprint sensor technology have raised the question about the usability of current methods when different sensors are employed for enrollment and verification; this is a fingerprint sensor interoperability problem. To provide insight into this problem and assess the status of state-of-the-art matching methods to tackle this problem, we first analyze the characteristics of fingerprints captured with different sensors, which makes cross-sensor matching a challenging problem. We demonstrate the importance of fingerprint enhancement methods for cross-sensor matching. Finally, we conduct a comparative study of state-of-the-art fingerprint recognition methods and provide insight into their abilities to address this problem. We performed experiments using a public database (FingerPass) that contains nine datasets captured with different sensors. We analyzed the effects of different sensors and found that cross-sensor matching performance deteriorates when different sensors are used for enrollment and verification. In view of our analysis, we propose future research directions for this problem.

  6. Using a cross-cheek anterolateral thigh flap for simultaneous correction of trismus and oral cancer.

    PubMed

    Chen, Chun-Chia; Wong, Tung-Yiu; Ou, Chun-Yen; Lee, Jing-Wei

    2010-01-01

    Oral cancers in association with trismus are commonly seen in clinical practice. Such a situation deserves special attention as it may complicate the tumour-ablative surgery and interfere with postoperative cancer surveillance. It follows that the simultaneous tackling of oral cancer and trismus should be pursued at any rate. In this presentation, a novel surgical approach using a cross-cheek anterolateral thigh (ALT) flap is introduced. With the special design in length, shape and orientation, this flap is capable of closing a wider defect area, sometimes extending across two functional regions (viz., posterior palate and trigonal area) without resort to two free flaps. As such, complex defects resulting from trismus release and tumour ablation can be readily repaired in a single stage. The advantages of such a technique include abundance in soft-tissue resources, proper flap quality and thickness, reliable blood supply, long and sizeable pedicle, ease in flap inset, need for only one recipient rather than two and the eradication of large area of mucosa that is predisposed to malignant transformation. The favourable outcome implicates that this innovative design could be a viable option in the management of such a clinical problem. Copyright (c) 2009. Published by Elsevier Ltd.

  7. Natural killer cells as a promising tool to tackle cancer-A review of sources, methodologies, and potentials.

    PubMed

    Preethy, Senthilkumar; Dedeepiya, Vidyasagar Devaprasad; Senthilkumar, Rajappa; Rajmohan, Mathaiyan; Karthick, Ramalingam; Terunuma, Hiroshi; Abraham, Samuel J K

    2017-07-04

    Immune cell-based therapies are emerging as a promising tool to tackle malignancies, both solid tumors and selected hematological tumors. Vast experiences in literature have documented their safety and added survival benefits when such cell-based therapies are combined with the existing treatment options. Numerous methodologies of processing and in vitro expansion protocols of immune cells, such as the dendritic cells, natural killer (NK) cells, NKT cells, αβ T cells, so-called activated T lymphocytes, γδ T cells, cytotoxic T lymphocytes, and lymphokine-activated killer cells, have been reported for use in cell-based therapies. Among this handful of immune cells of significance, the NK cells stand apart from the rest for not only their direct cytotoxic ability against cancer cells but also their added advantage, which includes their capability of (i) action through both innate and adaptive immune mechanism, (ii) tackling viruses too, giving benefits in conditions where viral infections culminate in cancer, and (iii) destroying cancer stem cells, thereby preventing resistance to chemotherapy and radiotherapy. This review thoroughly analyses the sources of such NK cells, methods for expansion, and the future potentials of taking the in vitro expanded allogeneic NK cells with good cytotoxic ability as a drug for treating cancer and/or viral infection and even as a prophylactic tool for prevention of cancer after initial remission.

  8. Obchs: AN Effective Harmony Search Algorithm with Oppositionbased Chaos-Enhanced Initialization for Solving Uncapacitated Facility Location Problems

    NASA Astrophysics Data System (ADS)

    Heidari, A. A.; Kazemizade, O.; Abbaspour, R. A.

    2015-12-01

    In this paper, a continuous harmony search (HS) approach is investigated for tackling the Uncapacitated Facility Location (UFL) task. This article proposes an efficient modified HS-based optimizer to improve the performance of HS on complex spatial tasks like UFL problems. For this aim, opposition-based learning (OBL) and chaotic patterns are utilized. The proposed technique is examined against several UFL benchmark challenges in specialized literature. Then, the modified HS is substantiated in detail and compared to the basic HS and some other methods. The results showed that new opposition-based chaotic HS (OBCHS) algorithm not only can exploit better solutions competently but it is able to outperform HS in solving UFL problems.

  9. Tackling children's road safety through edutainment: an evaluation of effectiveness.

    PubMed

    Zeedyk, M S; Wallace, L

    2003-08-01

    The burgeoning market in electronic media has encouraged a trend toward 'edutainment', where entertaining, media-based materials are used to facilitate educational outcomes. In this study, we evaluated the effectiveness of a video that has recently been released by a popular children's entertainment group to help tackle Britain's poor record on children's road safety. We wished to determine whether the video had an impact on either children's knowledge or parents' awareness of pedestrian skills, when used in a standard home-based fashion. A total of 120 families participated, all of whom had children 5 years of age. Half the families received videos at the beginning of the study, while the other half served as a control group against which to measure change in the treatment group. Data were gathered at baseline and again 1 month later, using a series of tailored questionnaire items. A robust pattern of null findings indicated that the video, when used in this casual fashion, had no educational impact on either parents or children. Crucially, however, parents strongly believed that it had. The discussion explores the implications of such a mismatch and highlights similarities with outcomes of other health education interventions.

  10. The success of recent land management efforts to tackle gully erosion in Northern France

    NASA Astrophysics Data System (ADS)

    Frankl, Amaury; Nyssen, Jan; Salvador, Pierre-Gil

    2017-04-01

    In the open-field agricultural landscapes of Europe, especially in the topographic-rolling loess-covered regions, soil erosion is an important problem. Here, small headwater catchments hold almost no permanent vegetation, and with few physical obstacles to reduce runoff velocities, runoff concentration along linear landscape elements (plot boundaries) or thalwegs frequently causes ephemeral gullies to occur - the latter reflecting the poor hydrogeomorphic condition of the land- and soilscape. To tackles this, and to remediate negative on- and off-site effects, land management efforts have multiplied over the past decades in many regions. This includes, amongst others measures, the implementation of vegetation barriers (French fascines, Dutch wilgenteendam). In the loess-dominated Aa river basin (640 km2) of northern France, where cropland accounts for 67% of the cover, mainly managed in open-field agro-industrial farming schemes, we investigated the effect of the implementation of vegetation barriers on ephemeral gully erosion dynamics, together with rainfall characteristics and cropland management. This was done from a spatially explicit study at the scale of 500 x 500 m grid cells using a diachronic analysis of historical aerial photographs (period 1947-2012). Fascines, introduced since 2001, were present in ca. 25% of the gully erosion sites. Spatio-temporal gully length variability was mainly driven by cumulative precipitation, and the presence of fascines could not significantly explain trends in decreasing gully lengths. In addition, the impact of fascines on mudflow hazards and on local sediment storage was also analysed. In sum, fascines clearly showed to have a local effect on the storage of sediment, but due to their limited implementation and poor maintenance, they did not decrease the landscape's vulnerability to gully erosion or mudflow hazards. Being increasingly implemented for erosion control in western Europe, this study points at the challenges

  11. A Thick-Restart Lanczos Algorithm with Polynomial Filtering for Hermitian Eigenvalue Problems

    DOE PAGES

    Li, Ruipeng; Xi, Yuanzhe; Vecharynski, Eugene; ...

    2016-08-16

    Polynomial filtering can provide a highly effective means of computing all eigenvalues of a real symmetric (or complex Hermitian) matrix that are located in a given interval, anywhere in the spectrum. This paper describes a technique for tackling this problem by combining a thick-restart version of the Lanczos algorithm with deflation ("locking'') and a new type of polynomial filter obtained from a least-squares technique. Furthermore, the resulting algorithm can be utilized in a “spectrum-slicing” approach whereby a very large number of eigenvalues and associated eigenvectors of the matrix are computed by extracting eigenpairs located in different subintervals independently from onemore » another.« less

  12. OpenMinds: creating a mental health workshop for teenagers to tackle stigma and raise awareness.

    PubMed

    Jones, Sammy; Sinha, Kathryn; Swinton, Martin; Millar, Christina; Rayment, Dane; Simmons, Meinou

    2011-09-01

    As a group of four clinical medical students from Cambridge University, we undertook a Student Selected Module (SSC- "OpenMinds") whereby we designed and delivered a workshop about mental health to year 9 pupils. The aim of our SSC was to produce an interactive, informative lesson which addressed the complex issues of stigma and discrimination against those suffering from a mental illness as well as teaching the pupils how to recognise mental health problems and provide them with guidance on how to seek help. We split a fifty minute session into the following sections: tackling stigma; how common mental illness is; celebrity examples; real life examples; role play; and small group work. To engage the pupils we used a combination of teaching modalities targeting all learning. We delivered the workshop to four separate classes and received feedback from the pupils after each. We used this feedback to adapt and improve our presentation and assess the efficacy. Feedback was overwhelmingly positive with the striking results of 101/109 pupils saying that they would recommend the workshop to a friend and 68/109 pupils saying they enjoyed all aspects. Our SSC built upon work by a contingent of trainee Psychiatrists who undertook a similar project of mental health education for teenagers, called "Heads above the rest", in Northern Ireland with great success. By continuing their work we were able to demonstrate that medical students can successfully complete the same project under the guidance of a Psychiatrist, thus increasing the sustainability of the project by reducing the time burden on the Psychiatrists. Participating in the project was also valuable to our own personal development of teaching skills.

  13. A 16-bit Coherent Ising Machine for One-Dimensional Ring and Cubic Graph Problems

    NASA Astrophysics Data System (ADS)

    Takata, Kenta; Marandi, Alireza; Hamerly, Ryan; Haribara, Yoshitaka; Maruo, Daiki; Tamate, Shuhei; Sakaguchi, Hiromasa; Utsunomiya, Shoko; Yamamoto, Yoshihisa

    2016-09-01

    Many tasks in our modern life, such as planning an efficient travel, image processing and optimizing integrated circuit design, are modeled as complex combinatorial optimization problems with binary variables. Such problems can be mapped to finding a ground state of the Ising Hamiltonian, thus various physical systems have been studied to emulate and solve this Ising problem. Recently, networks of mutually injected optical oscillators, called coherent Ising machines, have been developed as promising solvers for the problem, benefiting from programmability, scalability and room temperature operation. Here, we report a 16-bit coherent Ising machine based on a network of time-division-multiplexed femtosecond degenerate optical parametric oscillators. The system experimentally gives more than 99.6% of success rates for one-dimensional Ising ring and nondeterministic polynomial-time (NP) hard instances. The experimental and numerical results indicate that gradual pumping of the network combined with multiple spectral and temporal modes of the femtosecond pulses can improve the computational performance of the Ising machine, offering a new path for tackling larger and more complex instances.

  14. Can small institutes address some problems facing biomedical researchers?

    PubMed

    Sheetz, Michael P

    2014-11-01

    At a time of historically low National Institutes of Health funding rates and many problems with the conduct of research (unfunded mandates, disgruntled reviewers, and rampant paranoia), there is a concern that biomedical research as a profession is waning in the United States (see "Rescuing US biomedical research from its systemic flaws" by Alberts and colleagues in the Proceedings of the National Academy of Sciences). However, it is wonderful to discover something new and to tackle tough puzzles. If we could focus more of our effort on discussing scientific problems and doing research, then we could be more productive and perhaps happier. One potential solution is to focus efforts on small thematic institutes in the university structure that can provide a stimulating and supportive environment for innovation and exploration. With an open-lab concept, there are economies of scale that can diminish paperwork and costs, while providing greater access to state-of-the-art equipment. Merging multiple disciplines around a common theme can catalyze innovation, and this enables individuals to develop new concepts without giving up the credit they deserve, because it is usually clear who did the work. Small institutes do not solve larger systemic problems but rather enable collective efforts to address the noisome aspects of the system and foster an innovative community effort to address scientific problems. © 2014 Sheetz.

  15. The Effective-One-Body Approach to the General Relativistic Two Body Problem

    NASA Astrophysics Data System (ADS)

    Damour, Thibault; Nagar, Alessandro

    The two-body problem in General Relativity has been the subject of many analytical investigations. After reviewing some of the methods used to tackle this problem (and, more generally, the N-body problem), we focus on a new, recently introduced approach to the motion and radiation of (comparable mass) binary systems: the Effective One Body (EOB) formalism. We review the basic elements of this formalism, and discuss some of its recent developments. Several recent comparisons between EOB predictions and Numerical Relativity (NR) simulations have shown the aptitude of the EOB formalism to provide accurate descriptions of the dynamics and radiation of various binary systems (comprising black holes or neutron stars) in regimes that are inaccessible to other analytical approaches (such as the last orbits and the merger of comparable mass black holes). In synergy with NR simulations, post-Newtonian (PN) theory and Gravitational Self-Force (GSF) computations, the EOB formalism is likely to provide an efficient way of computing the very many accurate template waveforms that are needed for Gravitational Wave (GW) data analysis purposes.

  16. Health governance by collaboration: a case study on an area-based programme to tackle health inequalities in the Dutch city of the Hague.

    PubMed

    Plochg, Thomas; Schmidt, Melanie; Klazinga, Niek S; Stronks, Karien

    2013-12-01

    Area-based programmes are seen as a promising strategy for tackling health inequalities. In these programmes, local authorities and other local actors collaborate to employ health promoting interventions and policies. Little is known about the underlying processes of collaborative governance. To unravel this black box, we explored how the authority of The Hague, The Netherlands, developed a programme tackling health inequalities drawing on a collaborative mode of governance. Case study drawing on qualitative semi-structured interviews and document review. Data were inductively analysed against the concept of collaborative governance. The authority's ambition was to co-produce a programme on tackling health inequalities with local actors. Three stages could be distinguished in the governing process: (i) formulating policy objectives, (ii) translating policy objectives into interventions and (iii) executing health interventions. In the stage of formulating policy objectives, the collaboration led to a reframing of the initial objectives. Furthermore, the translation of the policy objectives into health interventions was rather pragmatic and loosely based on health needs and/or evidence. As a result, the concrete actions that ensued from the programme did not necessarily reflect the initial objectives. In a local system of health governance by collaboration, factors other than the stated policy objectives played a role, eventually undermining the effectiveness of the programme in reducing health inequalities. To be effective, the processes of collaborative governance underlying area-based programmes require the attention of the local authority, including the building and governing of networks, a competent public health workforce and supportive infrastructures.

  17. Tackling bioactive glass excessive in vitro bioreactivity: Preconditioning approaches for cell culture tests.

    PubMed

    Ciraldo, Francesca E; Boccardi, Elena; Melli, Virginia; Westhauser, Fabian; Boccaccini, Aldo R

    2018-05-21

    Bioactive glasses (BGs) are being increasingly considered for biomedical applications in bone and soft tissue replacement approaches thanks to their ability to form strong bonding with tissues. However, due to their high reactivity once in contact with water-based solutions BGs rapidly exchange ions with the surrounding environment leading in most cases to an undesired increase of the pH under static in vitro conditions (due to alkaline ion "burst release"), making difficult or even impossible to perform cell culture studies. Several pre-conditioning treatments have been therefore proposed in laboratories worldwide to limit this problem. This paper presents an overview of the different strategies that have been put forward to pre-treat BG samples to tackle the pH raise issue in order to enable cell biology studies. The paper also discusses the relevant criteria that determine the selection of the optimal pre-treatment depending on the BG composition and morphology (e.g. particles, scaffolds). Bioactive glasses (BGs), since their discovery in 1971 by L.L Hench, have been widely used for bone replacement and repair, and, more recently, they are becoming highly attractive for bone and soft tissue engineering applications. BGs have in fact the ability to form a strong bond with both hard and soft tissues once in contact with biological fluid. The enhanced interaction of BGs with the biological environment is based on their significant surface bioreactivity. This surface effect of BGs is, on the other hand, problematic for cell biology studies by standard (static) cell culture methods: an excessive bioreactivity leads in most cases to a rapid and dramatic increase of the pH of the surrounding medium, which results in cell death and makes cell culture tests on BG samples impossible. The BG research community has been aware of this for many years and numerous pre-treatments have been proposed by different groups worldwide to limit this problem. For the first time, we have

  18. Mapping injustice, visualizing equity: why theory, metaphors and images matter in tackling inequalities.

    PubMed

    Krieger, N; Dorling, D; McCartney, G

    2012-03-01

    This symposia discussed "Mapping injustice, visualizing equity: why theory, metaphors and images matter in tackling inequalities". It sought to provoke critical thinking about the current theories used to analyze the health impact of injustice, variously referred to as "health inequalities" in the UK, "social inequalities in health" in the US, and "health inequities" more globally. Our focus was the types of explanations, images, and metaphors these theories employ. Building on frameworks that emphasize politics, agency, and accountability, we suggested that it was essential to engage the general public in the politics of health inequities if progress is to be made. We showcased some examples of such engagement before inviting the audience to consider how this might apply in their own areas of responsibility. Copyright © 2012 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  19. Tackling the social determinants of inequalities in health during Phase V of the Healthy Cities Project in Europe.

    PubMed

    Ritsatakis, Anna; Ostergren, Per-Olof; Webster, Premila

    2015-06-01

    The WHO European Healthy Cities Network has from its inception aimed at tackling inequalities in health. In carrying out an evaluation of Phase V of the project (2009-13), an attempt was made to examine how far the concept of equity in health is understood and accepted; whether cities had moved further from a disease/medical model to looking at the social determinants of inequalities in health; how far the HC project contributed to cities determining the extent and causes of inequalities in health; what efforts were made to tackle such inequalities and how far inequalities in health may have increased or decreased during Phase V. A broader range of resources was utilized for this evaluation than in previous phases of the project. These indicated that most cities were definitely looking at the broader determinants. Equality in health was better understood and had been included as a value in a range of city policies. This was facilitated by stronger involvement of the HC project in city planning processes. Although almost half the cities participating had prepared a City Health Profile, only few cities had the necessary local level data to monitor changes in inequalities in health. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  20. A wideband fast multipole boundary element method for half-space/plane-symmetric acoustic wave problems

    NASA Astrophysics Data System (ADS)

    Zheng, Chang-Jun; Chen, Hai-Bo; Chen, Lei-Lei

    2013-04-01

    This paper presents a novel wideband fast multipole boundary element approach to 3D half-space/plane-symmetric acoustic wave problems. The half-space fundamental solution is employed in the boundary integral equations so that the tree structure required in the fast multipole algorithm is constructed for the boundary elements in the real domain only. Moreover, a set of symmetric relations between the multipole expansion coefficients of the real and image domains are derived, and the half-space fundamental solution is modified for the purpose of applying such relations to avoid calculating, translating and saving the multipole/local expansion coefficients of the image domain. The wideband adaptive multilevel fast multipole algorithm associated with the iterative solver GMRES is employed so that the present method is accurate and efficient for both lowand high-frequency acoustic wave problems. As for exterior acoustic problems, the Burton-Miller method is adopted to tackle the fictitious eigenfrequency problem involved in the conventional boundary integral equation method. Details on the implementation of the present method are described, and numerical examples are given to demonstrate its accuracy and efficiency.

  1. Size and consistency of problem-solving consultation outcomes: an empirical analysis.

    PubMed

    Hurwitz, Jason T; Kratochwill, Thomas R; Serlin, Ronald C

    2015-04-01

    In this study, we analyzed extant data to evaluate the variability and magnitude of students' behavior change outcomes (academic, social, and behavioral) produced by consultants through problem-solving consultation with teachers. Research questions were twofold: (a) Do consultants produce consistent and sizeable positive student outcomes across their cases as measured through direct and frequent assessment? and (b) What proportion of variability in student outcomes is attributable to consultants? Analyses of extant data collected from problem-solving consultation outcome studies that used single-case, time-series AB designs with multiple participants were analyzed. Four such studies ultimately met the inclusion criteria for the extant data, comprising 124 consultants who worked with 302 school teachers regarding 453 individual students. Consultants constituted the independent variable, while the primary dependent variable was a descriptive effect size based on student behavior change as measured by (a) curriculum-based measures, (b) permanent products, or (c) direct observations. Primary analyses involved visual and statistical evaluation of effect size magnitude and variability observed within and between consultants and studies. Given the nested nature of the data, multilevel analyses were used to assess consultant effects on student outcomes. Results suggest that consultants consistently produced positive effect sizes on average across their cases, but outcomes varied between consultants. Findings also indicated that consultants, teachers, and the corresponding studies accounted for a significant proportion of variability in student outcomes. This investigation advances the use of multilevel and integrative data analyses to evaluate consultation outcomes and extends research on problem-solving consultation, consultant effects, and meta-analysis of case study AB designs. Practical implications for evaluating consultation service delivery in school settings are

  2. Hypertension in Black and Other Populations: Environmental Factors and Approaches to Management

    PubMed Central

    Hosten, Adrian O.

    1980-01-01

    Hypertension is a major health problem for industrialized as well as developing countries, especially those with sizeable black populations. The author analyzes various aspects of hypertension in black and other populations with emphasis on contributing factors and therapeutic approaches. PMID:7365811

  3. Tackling obesity: new therapeutic agents for assisted weight loss

    PubMed Central

    Karam, JG; McFarlane, SI

    2010-01-01

    The pandemic of overweight and obesity continues to rise in an alarming rate in western countries and around the globe representing a major public health challenge in desperate need for new strategies tackling obesity. In the United States nearly two thirds of the population is overweight or obese. Worldwide the number of persons who are overweight or obese exceeded 1.6 billion. These rising figures have been clearly associated with increased morbidity and mortality. For example, in the Framingham study, the risk of death increases with each additional pound of weight gain even in the relatively younger population between 30 and 42 years of age. Overweight and obesity are also associated with increased co-morbid conditions such as diabetes, hypertension and cardiovascular disease as well as certain types of cancer. In this review we discuss the epidemic of obesity, highlighting the pathophysiologic mechanisms of weight gain. We also provide an overview of the assessment of overweight and obese individuals discussing possible secondary causes of obesity. In a detailed section we discuss the currently approved therapeutic interventions for obesity highlighting their mechanisms of action and evidence of their efficacy and safety as provided in clinical trials. Finally, we discuss novel therapeutic interventions that are in various stages of development with a special section on the weight loss effects of anti-diabetic medications. These agents are particularly attractive options for our growing population of obese diabetic individuals. PMID:21437080

  4. [Repercussions of the Maria da Penha law in tackling gender violence].

    PubMed

    Meneghel, Stela Nazareth; Mueller, Betânia; Collaziol, Marceli Emer; de Quadros, Maíra Meneghel

    2013-03-01

    This paper presents the declarations about the Maria da Penha law made by a sample of women victims and care workers who handle situations of gender violence in the city of Porto Alegre. The data are part of a study that investigated the critical path followed by women who decide to denounce violence. The statements were selected from 45 semi-structured interviews answered by 21 women and 25 professionals from the police, legal, social and health services and nongovernmental institutions. Data were analyzed using NVivo software and one of the categories selected was the Maria da Penha law. Most respondents mentioned the positive and innovatory aspects of the law, though they also pointed out its limitations. The care workers see the legal device as an important tool for tackling violence, aligned with international conventions, bringing innovations and broadening women's access to justice. In terms of weaknesses, both women and care workers stress the inefficiency in the implementation of protective measures, the lack of material resources and manpower, the fragmentation of the health care network and the movement of conservative sectors in society to delegitimize the law.

  5. A simulated annealing approach for redesigning a warehouse network problem

    NASA Astrophysics Data System (ADS)

    Khairuddin, Rozieana; Marlizawati Zainuddin, Zaitul; Jiun, Gan Jia

    2017-09-01

    Now a day, several companies consider downsizing their distribution networks in ways that involve consolidation or phase-out of some of their current warehousing facilities due to the increasing competition, mounting cost pressure and taking advantage on the economies of scale. Consequently, the changes on economic situation after a certain period of time require an adjustment on the network model in order to get the optimal cost under the current economic conditions. This paper aimed to develop a mixed-integer linear programming model for a two-echelon warehouse network redesign problem with capacitated plant and uncapacitated warehouses. The main contribution of this study is considering capacity constraint for existing warehouses. A Simulated Annealing algorithm is proposed to tackle with the proposed model. The numerical solution showed the model and method of solution proposed was practical.

  6. Nonlinear programming for classification problems in machine learning

    NASA Astrophysics Data System (ADS)

    Astorino, Annabella; Fuduli, Antonio; Gaudioso, Manlio

    2016-10-01

    We survey some nonlinear models for classification problems arising in machine learning. In the last years this field has become more and more relevant due to a lot of practical applications, such as text and web classification, object recognition in machine vision, gene expression profile analysis, DNA and protein analysis, medical diagnosis, customer profiling etc. Classification deals with separation of sets by means of appropriate separation surfaces, which is generally obtained by solving a numerical optimization model. While linear separability is the basis of the most popular approach to classification, the Support Vector Machine (SVM), in the recent years using nonlinear separating surfaces has received some attention. The objective of this work is to recall some of such proposals, mainly in terms of the numerical optimization models. In particular we tackle the polyhedral, ellipsoidal, spherical and conical separation approaches and, for some of them, we also consider the semisupervised versions.

  7. Trials for the cosmological 7Li problem with 7Be beams at CRIB and collaborating studies

    NASA Astrophysics Data System (ADS)

    Hayakawa, S.

    2017-09-01

    For many years, the cosmological ^7 Li problem has been tackled from various aspects. The nuclear reaction data have also been improved, but still there remains some ambiguities. We review our experimental plans to measure the cross sections of three key reactions which act to destroy ^7 Be during the Big-Bang Nucleosynthesis (BBN). These experiments are all based on ^7 Be beams produced at Center-for-Nuclear-Study Radioactive Ion Beam separator (CRIB) in collaborations mainly with research groups from INFN-LNS and RCNP. The preliminary result of the previous experiment and the future plan are discussed.

  8. Linguistic Challenges in the Mathematical Register for EFL Learners: Linguistic and Multimodal Strategies to Help Learners Tackle Mathematics Word Problems

    ERIC Educational Resources Information Center

    Chan, Simon

    2015-01-01

    In learning mathematics through English, one of the major challenges facing English as a Foreign Language (EFL) learners is understanding the language used to present word problems in mathematics texts. Without comprehending such language, learners are not able to carry out the targeted calculations no matter how familiar they are with the…

  9. How to Tackle Key Challenges in the Promotion of Physical Activity among Older Adults (65+): The AEQUIPA Network Approach

    PubMed Central

    Forberger, Sarah; Bammann, Karin; Bauer, Jürgen; Boll, Susanne; Bolte, Gabriele; Brand, Tilman; Hein, Andreas; Koppelin, Frauke; Lippke, Sonia; Meyer, Jochen; Pischke, Claudia R.; Voelcker-Rehage, Claudia; Zeeb, Hajo

    2017-01-01

    The paper introduces the theoretical framework and methods/instruments used by the Physical Activity and Health Equity: Primary Prevention for Healthy Ageing (AEQUIPA) prevention research network as an interdisciplinary approach to tackle key challenges in the promotion of physical activity among older people (65+). Drawing on the social-ecological model, the AEQUIPA network developed an interdisciplinary methodological design including quantitative/qualitative studies and systematic reviews, while combining expertise from diverse fields: public health, psychology, urban planning, sports sciences, health technology and geriatrics. AEQUIPA tackles key challenges when promoting physical activity (PA) in older adults: tailoring of interventions, fostering community readiness and participation, strengthening intersectoral collaboration, using new technological devices and evaluating intervention generated inequalities. AEQUIPA aims to strengthen the evidence base for age-specific preventive PA interventions and to yield new insights into the explanatory power of individual and contextual factors. Currently, the empirical work is still underway. First experiences indicate that the network has achieved a strong regional linkage with communities, local stakeholders and individuals. However, involving inactive persons and individuals from minority groups remained challenging. A review of existing PA intervention studies among the elderly revealed the potential to assess equity effects. The results will add to the theoretical and methodological discussion on evidence-based age-specific PA interventions and will contribute to the discussion about European and national health targets. PMID:28375177

  10. How to Tackle Key Challenges in the Promotion of Physical Activity among Older Adults (65+): The AEQUIPA Network Approach.

    PubMed

    Forberger, Sarah; Bammann, Karin; Bauer, Jürgen; Boll, Susanne; Bolte, Gabriele; Brand, Tilman; Hein, Andreas; Koppelin, Frauke; Lippke, Sonia; Meyer, Jochen; Pischke, Claudia R; Voelcker-Rehage, Claudia; Zeeb, Hajo

    2017-04-04

    The paper introduces the theoretical framework and methods/instruments used by the Physical Activity and Health Equity: Primary Prevention for Healthy Ageing (AEQUIPA) prevention research network as an interdisciplinary approach to tackle key challenges in the promotion of physical activity among older people (65+). Drawing on the social-ecological model, the AEQUIPA network developed an interdisciplinary methodological design including quantitative/qualitative studies and systematic reviews, while combining expertise from diverse fields: public health, psychology, urban planning, sports sciences, health technology and geriatrics. AEQUIPA tackles key challenges when promoting physical activity (PA) in older adults: tailoring of interventions, fostering community readiness and participation, strengthening intersectoral collaboration, using new technological devices and evaluating intervention generated inequalities. AEQUIPA aims to strengthen the evidence base for age-specific preventive PA interventions and to yield new insights into the explanatory power of individual and contextual factors. Currently, the empirical work is still underway. First experiences indicate that thenetwork has achieved a strong regional linkage with communities, local stakeholders and individuals. However, involving inactive persons and individuals from minority groups remained challenging. A review of existing PA intervention studies among the elderly revealed the potential to assess equity effects. The results will add to the theoretical and methodological discussion on evidence-based age-specific PA interventions and will contribute to the discussion about European and national health targets.

  11. Universities Have the Responsibility to Tackle the World's Toughest Problems

    ERIC Educational Resources Information Center

    Klitgaard, Robert

    2008-01-01

    Issues that seem intractable not only dominate our news but paralyze our governments. Corruption. Immigration. Religious and cultural conflict. When such issues are raised, too often we roll our eyes and give up before we begin. Using the example of corruption, the author presents ideas for how colleges and universities can help resolve…

  12. Public health nutrition in the civil service (England): approaches to tackling obesity.

    PubMed

    Blackshaw, J R

    2016-08-01

    The seriousness and scale of the physical, psychological, economic and societal consequences relating to poor diets, inactivity and obesity is unprecedented. Consequently, the contextual factors underpinning the work of a nutritionist in the civil service are complex and significant; however, there are real opportunities to make a difference and help improve the health of the nation. The present paper describes the delivery of public health nutrition through two work programmes, namely action to support young people develop healthier lifestyle choices and more recently the investigation and deployment of local insights to develop action to tackle obesity. Combining the application of nutrition expertise along with broader skills and approaches has enabled the translation of research and evidence into programmes of work to better the public's health. It is evident that the appropriate evaluation of such approaches has helped to deliver engaging and practical learning opportunities for young people. Furthermore, efforts to build on local intelligence and seek collaborative development can help inform the evidence base and seek to deliver public health approaches, which resonate with how people live their lives.

  13. Automated bond order assignment as an optimization problem.

    PubMed

    Dehof, Anna Katharina; Rurainski, Alexander; Bui, Quang Bao Anh; Böcker, Sebastian; Lenhof, Hans-Peter; Hildebrandt, Andreas

    2011-03-01

    Numerous applications in Computational Biology process molecular structures and hence strongly rely not only on correct atomic coordinates but also on correct bond order information. For proteins and nucleic acids, bond orders can be easily deduced but this does not hold for other types of molecules like ligands. For ligands, bond order information is not always provided in molecular databases and thus a variety of approaches tackling this problem have been developed. In this work, we extend an ansatz proposed by Wang et al. that assigns connectivity-based penalty scores and tries to heuristically approximate its optimum. In this work, we present three efficient and exact solvers for the problem replacing the heuristic approximation scheme of the original approach: an A*, an ILP and an fixed-parameter approach (FPT) approach. We implemented and evaluated the original implementation, our A*, ILP and FPT formulation on the MMFF94 validation suite and the KEGG Drug database. We show the benefit of computing exact solutions of the penalty minimization problem and the additional gain when computing all optimal (or even suboptimal) solutions. We close with a detailed comparison of our methods. The A* and ILP solution are integrated into the open-source C++ LGPL library BALL and the molecular visualization and modelling tool BALLView and can be downloaded from our homepage www.ball-project.org. The FPT implementation can be downloaded from http://bio.informatik.uni-jena.de/software/.

  14. A capacitated vehicle routing problem with order available time in e-commerce industry

    NASA Astrophysics Data System (ADS)

    Liu, Ling; Li, Kunpeng; Liu, Zhixue

    2017-03-01

    In this article, a variant of the well-known capacitated vehicle routing problem (CVRP) called the capacitated vehicle routing problem with order available time (CVRPOAT) is considered, which is observed in the operations of the current e-commerce industry. In this problem, the orders are not available for delivery at the beginning of the planning period. CVRPOAT takes all the assumptions of CVRP, except the order available time, which is determined by the precedent order picking and packing stage in the warehouse of the online grocer. The objective is to minimize the sum of vehicle completion times. An efficient tabu search algorithm is presented to tackle the problem. Moreover, a Lagrangian relaxation algorithm is developed to obtain the lower bounds of reasonably sized problems. Based on the test instances derived from benchmark data, the proposed tabu search algorithm is compared with a published related genetic algorithm, as well as the derived lower bounds. Also, the tabu search algorithm is compared with the current operation strategy of the online grocer. Computational results indicate that the gap between the lower bounds and the results of the tabu search algorithm is small and the tabu search algorithm is superior to the genetic algorithm. Moreover, the CVRPOAT formulation together with the tabu search algorithm performs much better than the current operation strategy of the online grocer.

  15. A genetic algorithm for a bi-objective mathematical model for dynamic virtual cell formation problem

    NASA Astrophysics Data System (ADS)

    Moradgholi, Mostafa; Paydar, Mohammad Mahdi; Mahdavi, Iraj; Jouzdani, Javid

    2016-09-01

    Nowadays, with the increasing pressure of the competitive business environment and demand for diverse products, manufacturers are force to seek for solutions that reduce production costs and rise product quality. Cellular manufacturing system (CMS), as a means to this end, has been a point of attraction to both researchers and practitioners. Limitations of cell formation problem (CFP), as one of important topics in CMS, have led to the introduction of virtual CMS (VCMS). This research addresses a bi-objective dynamic virtual cell formation problem (DVCFP) with the objective of finding the optimal formation of cells, considering the material handling costs, fixed machine installation costs and variable production costs of machines and workforce. Furthermore, we consider different skills on different machines in workforce assignment in a multi-period planning horizon. The bi-objective model is transformed to a single-objective fuzzy goal programming model and to show its performance; numerical examples are solved using the LINGO software. In addition, genetic algorithm (GA) is customized to tackle large-scale instances of the problems to show the performance of the solution method.

  16. Tackling health inequalities: moving theory to action

    PubMed Central

    Signal, Louise; Martin, Jennifer; Reid, Papaarangi; Carroll, Christopher; Howden-Chapman, Philippa; Ormsby, Vera Keefe; Richards, Ruth; Robson, Bridget; Wall, Teresa

    2007-01-01

    Background This paper reports on health inequalities awareness-raising workshops conducted with senior New Zealand health sector staff as part of the Government's goal of reducing inequalities in health, education, employment and housing. Methods The workshops were based on a multi-method needs assessment with senior staff in key health institutions. The workshops aimed to increase the knowledge and skills of health sector staff to act on, and advocate for, eliminating inequalities in health. They were practical, evidence-based, and action oriented and took a social approach to the causes of inequalities in health. The workshops used ethnicity as a case study and explored racism as a driver of inequalities. They focused on the role of institutionalized racism, or racism that is built into health sector institutions. Institutional theory provided a framework for participants to analyse how their institutions create and maintain inequalities and how they can act to change this. Results Participants identified a range of institutional mechanisms that promote inequalities and a range of ways to address them including: undertaking further training, using Māori (the indigenous people) models of health in policy-making, increasing Māori participation and partnership in decision making, strengthening sector relationships with iwi (tribes), funding and supporting services provided 'by Māori for Māori', ensuring a strategic approach to intersectoral work, encouraging stronger community involvement in the work of the institution, requiring all evaluations to assess impact on inequalities, and requiring the sector to report on progress in addressing health inequalities. The workshops were rated highly by participants, who indicated increased commitment to tackle inequalities as a result of the training. Discussion Government and sector leadership were critical to the success of the workshops and subsequent changes in policy and practice. The use of locally adapted equity

  17. Tackling health inequalities: moving theory to action.

    PubMed

    Signal, Louise; Martin, Jennifer; Reid, Papaarangi; Carroll, Christopher; Howden-Chapman, Philippa; Ormsby, Vera Keefe; Richards, Ruth; Robson, Bridget; Wall, Teresa

    2007-10-03

    This paper reports on health inequalities awareness-raising workshops conducted with senior New Zealand health sector staff as part of the Government's goal of reducing inequalities in health, education, employment and housing. The workshops were based on a multi-method needs assessment with senior staff in key health institutions. The workshops aimed to increase the knowledge and skills of health sector staff to act on, and advocate for, eliminating inequalities in health. They were practical, evidence-based, and action oriented and took a social approach to the causes of inequalities in health. The workshops used ethnicity as a case study and explored racism as a driver of inequalities. They focused on the role of institutionalized racism, or racism that is built into health sector institutions. Institutional theory provided a framework for participants to analyse how their institutions create and maintain inequalities and how they can act to change this. Participants identified a range of institutional mechanisms that promote inequalities and a range of ways to address them including: undertaking further training, using Māori (the indigenous people) models of health in policy-making, increasing Māori participation and partnership in decision making, strengthening sector relationships with iwi (tribes), funding and supporting services provided 'by Māori for Māori', ensuring a strategic approach to intersectoral work, encouraging stronger community involvement in the work of the institution, requiring all evaluations to assess impact on inequalities, and requiring the sector to report on progress in addressing health inequalities. The workshops were rated highly by participants, who indicated increased commitment to tackle inequalities as a result of the training. Government and sector leadership were critical to the success of the workshops and subsequent changes in policy and practice. The use of locally adapted equity tools, requiring participants to

  18. Designing, implementing and evaluating an online problem-based learning (PBL) environment--a pilot study.

    PubMed

    Ng, Manwa L; Bridges, Susan; Law, Sam Po; Whitehill, Tara

    2014-01-01

    Problem-based learning (PBL) has been shown to be effective for promoting student competencies in self-directed and collaborative learning, critical thinking, self-reflection and tackling novel situations. However, the need for face-to-face interactions at the same place and time severely limits the potential of traditional PBL. The requirements of space and for meeting at a specific location at the same time create timetabling difficulties. Such limitations need to be tackled before all potentials of PBL learning can be realized. The present study aimed at designing and implementing an online PBL environment for undergraduate speech/language pathology students, and assessing the associated pedagogical effectiveness. A group of eight PBL students were randomly selected to participate in the study. They underwent 4 weeks of online PBL using Adobe Connect. Upon completion of the experiment, they were assessed via a self-reported questionnaire and quantitative comparison with traditional PBL students based on the same written assignment. The questionnaire revealed that all participating students enjoyed online PBL, without any perceived negative effects on learning. Online PBL unanimously saved the students travel time to and from school. Statistical analysis indicated no significant difference in assignment grades between the online and traditional PBL groups, indicating that online PBL learning appears to be similarly effective as traditional face-to-face PBL learning.

  19. Dynamic Grover search: applications in recommendation systems and optimization problems

    NASA Astrophysics Data System (ADS)

    Chakrabarty, Indranil; Khan, Shahzor; Singh, Vanshdeep

    2017-06-01

    In the recent years, we have seen that Grover search algorithm (Proceedings, 28th annual ACM symposium on the theory of computing, pp. 212-219, 1996) by using quantum parallelism has revolutionized the field of solving huge class of NP problems in comparisons to classical systems. In this work, we explore the idea of extending Grover search algorithm to approximate algorithms. Here we try to analyze the applicability of Grover search to process an unstructured database with a dynamic selection function in contrast to the static selection function used in the original work (Grover in Proceedings, 28th annual ACM symposium on the theory of computing, pp. 212-219, 1996). We show that this alteration facilitates us to extend the application of Grover search to the field of randomized search algorithms. Further, we use the dynamic Grover search algorithm to define the goals for a recommendation system based on which we propose a recommendation algorithm which uses binomial similarity distribution space giving us a quadratic speedup over traditional classical unstructured recommendation systems. Finally, we see how dynamic Grover search can be used to tackle a wide range of optimization problems where we improve complexity over existing optimization algorithms.

  20. Lead fishing weights and other fishing tackle in selected waterbirds

    USGS Publications Warehouse

    Franson, J.C.; Hansen, Scott P.; Creekmore, T.E.; Brand, C.J.; Evers, D.C.; Duerr, A.E.; DeStefano, S.

    2003-01-01

    From 1995 through 1999, 2,240 individuals of 28 species of waterbirds were examined in the United States for ingested lead fishing weights. A combination of radiography and visual examination of stomachs was used to search for lead weights and blood and liver samples from live birds and carcasses, respectively, were collected for lead analysis. Ingested lead weights were found most frequently in the Common Loon (Gavia immer) (11 of 313 = 3.5%) and Brown Pelican (Pelecanus occidentalis) (10 of 365 = 2.7%), but also in one of 81 (1.2%) Double-crested Cormorants (Phalacrocorax auritus) and one of 11 (9.1%) Black-crowned Night Herons (Nycticorax nycticorax). Birds with ingested lead fishing weights (including split shot, jig heads, and egg, bell, and pyramid sinkers) were found in California, Florida, Maine, New Hampshire, North Carolina, and Wisconsin. The size and mass of ingested lead weights ranged from split shot of 7 mm in the longest dimension, weighing less than 2 g, to a 22 ?? 39 mm pyramid sinker that weighed 78.2 g. Six ingested lead weights were more than 25.4 mm in the longest dimension. Lead concentrations in the blood and liver of birds with lead fishing weights in their stomachs ranged up to 13.9 ppm and 26.0 ppm (wet weight basis), respectively. During the study, we also noted the presence of ingested or entangled fishing tackle, with no associated lead weights, in eight species.

  1. Redesigning the Quantum Mechanics Curriculum to Incorporate Problem Solving Using a Computer Algebra System

    NASA Astrophysics Data System (ADS)

    Roussel, Marc R.

    1999-10-01

    One of the traditional obstacles to learning quantum mechanics is the relatively high level of mathematical proficiency required to solve even routine problems. Modern computer algebra systems are now sufficiently reliable that they can be used as mathematical assistants to alleviate this difficulty. In the quantum mechanics course at the University of Lethbridge, the traditional three lecture hours per week have been replaced by two lecture hours and a one-hour computer-aided problem solving session using a computer algebra system (Maple). While this somewhat reduces the number of topics that can be tackled during the term, students have a better opportunity to familiarize themselves with the underlying theory with this course design. Maple is also available to students during examinations. The use of a computer algebra system expands the class of feasible problems during a time-limited exercise such as a midterm or final examination. A modern computer algebra system is a complex piece of software, so some time needs to be devoted to teaching the students its proper use. However, the advantages to the teaching of quantum mechanics appear to outweigh the disadvantages.

  2. Accuracy of Time Integration Approaches for Stiff Magnetohydrodynamics Problems

    NASA Astrophysics Data System (ADS)

    Knoll, D. A.; Chacon, L.

    2003-10-01

    The simulation of complex physical processes with multiple time scales presents a continuing challenge to the computational plasma physisist due to the co-existence of fast and slow time scales. Within computational plasma physics, practitioners have developed and used linearized methods, semi-implicit methods, and time splitting in an attempt to tackle such problems. All of these methods are understood to generate numerical error. We are currently developing algorithms which remove such error for MHD problems [1,2]. These methods do not rely on linearization or time splitting. We are also attempting to analyze the errors introduced by existing ``implicit'' methods using modified equation analysis (MEA) [3]. In this presentation we will briefly cover the major findings in [3]. We will then extend this work further into MHD. This analysis will be augmented with numerical experiments with the hope of gaining insight, particularly into how these errors accumulate over many time steps. [1] L. Chacon,. D.A. Knoll, J.M. Finn, J. Comput. Phys., vol. 178, pp. 15-36 (2002) [2] L. Chacon and D.A. Knoll, J. Comput. Phys., vol. 188, pp. 573-592 (2003) [3] D.A. Knoll , L. Chacon, L.G. Margolin, V.A. Mousseau, J. Comput. Phys., vol. 185, pp. 583-611 (2003)

  3. An outer approximation method for the road network design problem

    PubMed Central

    2018-01-01

    Best investment in the road infrastructure or the network design is perceived as a fundamental and benchmark problem in transportation. Given a set of candidate road projects with associated costs, finding the best subset with respect to a limited budget is known as a bilevel Discrete Network Design Problem (DNDP) of NP-hard computationally complexity. We engage with the complexity with a hybrid exact-heuristic methodology based on a two-stage relaxation as follows: (i) the bilevel feature is relaxed to a single-level problem by taking the network performance function of the upper level into the user equilibrium traffic assignment problem (UE-TAP) in the lower level as a constraint. It results in a mixed-integer nonlinear programming (MINLP) problem which is then solved using the Outer Approximation (OA) algorithm (ii) we further relax the multi-commodity UE-TAP to a single-commodity MILP problem, that is, the multiple OD pairs are aggregated to a single OD pair. This methodology has two main advantages: (i) the method is proven to be highly efficient to solve the DNDP for a large-sized network of Winnipeg, Canada. The results suggest that within a limited number of iterations (as termination criterion), global optimum solutions are quickly reached in most of the cases; otherwise, good solutions (close to global optimum solutions) are found in early iterations. Comparative analysis of the networks of Gao and Sioux-Falls shows that for such a non-exact method the global optimum solutions are found in fewer iterations than those found in some analytically exact algorithms in the literature. (ii) Integration of the objective function among the constraints provides a commensurate capability to tackle the multi-objective (or multi-criteria) DNDP as well. PMID:29590111

  4. An outer approximation method for the road network design problem.

    PubMed

    Asadi Bagloee, Saeed; Sarvi, Majid

    2018-01-01

    Best investment in the road infrastructure or the network design is perceived as a fundamental and benchmark problem in transportation. Given a set of candidate road projects with associated costs, finding the best subset with respect to a limited budget is known as a bilevel Discrete Network Design Problem (DNDP) of NP-hard computationally complexity. We engage with the complexity with a hybrid exact-heuristic methodology based on a two-stage relaxation as follows: (i) the bilevel feature is relaxed to a single-level problem by taking the network performance function of the upper level into the user equilibrium traffic assignment problem (UE-TAP) in the lower level as a constraint. It results in a mixed-integer nonlinear programming (MINLP) problem which is then solved using the Outer Approximation (OA) algorithm (ii) we further relax the multi-commodity UE-TAP to a single-commodity MILP problem, that is, the multiple OD pairs are aggregated to a single OD pair. This methodology has two main advantages: (i) the method is proven to be highly efficient to solve the DNDP for a large-sized network of Winnipeg, Canada. The results suggest that within a limited number of iterations (as termination criterion), global optimum solutions are quickly reached in most of the cases; otherwise, good solutions (close to global optimum solutions) are found in early iterations. Comparative analysis of the networks of Gao and Sioux-Falls shows that for such a non-exact method the global optimum solutions are found in fewer iterations than those found in some analytically exact algorithms in the literature. (ii) Integration of the objective function among the constraints provides a commensurate capability to tackle the multi-objective (or multi-criteria) DNDP as well.

  5. New modified multi-level residue harmonic balance method for solving nonlinearly vibrating double-beam problem

    NASA Astrophysics Data System (ADS)

    Rahman, Md. Saifur; Lee, Yiu-Yin

    2017-10-01

    In this study, a new modified multi-level residue harmonic balance method is presented and adopted to investigate the forced nonlinear vibrations of axially loaded double beams. Although numerous nonlinear beam or linear double-beam problems have been tackled and solved, there have been few studies of this nonlinear double-beam problem. The geometric nonlinear formulations for a double-beam model are developed. The main advantage of the proposed method is that a set of decoupled nonlinear algebraic equations is generated at each solution level. This heavily reduces the computational effort compared with solving the coupled nonlinear algebraic equations generated in the classical harmonic balance method. The proposed method can generate the higher-level nonlinear solutions that are neglected by the previous modified harmonic balance method. The results from the proposed method agree reasonably well with those from the classical harmonic balance method. The effects of damping, axial force, and excitation magnitude on the nonlinear vibrational behaviour are examined.

  6. Impact of the parenting style of foster parents on the behaviour problems of foster children.

    PubMed

    Fuentes, M J; Salas, M D; Bernedo, I M; García-Martín, M A

    2015-09-01

    Few studies have analysed the effects of the parenting style used by foster carers on children's behaviour problems. This study examines the role played by the quality of the emotional relationship with foster carers and the kind of discipline they use as regard internalizing and externalizing problems among foster children. Participants were 104 foster children (56 boys and 48 girls) and their respective foster families. The Child Behaviour Checklist, the Affect and Communication Scale, and the Rules and Demands Scale were completed by foster parents. A series of linear regression analyses were performed using the stepwise method. The main findings were as follows: an authoritarian parenting style explained the internalizing problems presented by foster children (11% of the variance); criticism/rejection, authoritarian parenting and permissive parenting explained externalizing problems (37% of the variance); and criticism/rejection and authoritarian parenting explained total problems (29% of the variance). These results indicate that criticism/rejection on the part of foster parents, as well as the use of inappropriate parenting styles (authoritarian and permissive), has an important effect in relation to the behaviour problems of foster children. This highlights the key role that foster carers play in terms of tackling the behaviour problems that foster children present. The findings also suggest that preparation for fostering should focus especially on ways of helping foster parents both to acquire positive parenting strategies and to avoid authoritarian and permissive parenting. © 2014 John Wiley & Sons Ltd.

  7. A complex approach to the blue-loop problem

    NASA Astrophysics Data System (ADS)

    Ostrowski, Jakub; Daszynska-Daszkiewicz, Jadwiga

    2015-08-01

    The problem of the blue loops during the core helium burning, outstanding for almost fifty years, is one of the most difficult and poorly understood problems in stellar astrophysics. Most of the work focused on the blue loops done so far has been performed with old stellar evolution codes and with limited computational resources. In the end the obtained conclusions were based on a small sample of models and could not have taken into account more advanced effects and interactions between them.The emergence of the blue loops depends on many details of the evolution calculations, in particular on chemical composition, opacity, mixing processes etc. The non-linear interactions between these factors contribute to the statement that in most cases it is hard to predict without a precise stellar modeling whether a loop will emerge or not. The high sensitivity of the blue loops to even small changes of the internal structure of a star yields one more issue: a sensitivity to numerical problems, which are common in calculations of stellar models on advanced stages of the evolution.To tackle this problem we used a modern stellar evolution code MESA. We calculated a large grid of evolutionary tracks (about 8000 models) with masses in the range of 3.0 - 25.0 solar masses from the zero age main sequence to the depletion of helium in the core. In order to make a comparative analysis, we varied metallicity, helium abundance and different mixing parameters resulting from convective overshooting, rotation etc.The better understanding of the properties of the blue loops is crucial for our knowledge of the population of blue supergiants or pulsating variables such as Cepheids, α-Cygni or Slowly Pulsating B-type supergiants. In case of more massive models it is also of great importance for studies of the progenitors of supernovae.

  8. Exploring different strategies for imbalanced ADME data problem: case study on Caco-2 permeability modeling.

    PubMed

    Pham-The, Hai; Casañola-Martin, Gerardo; Garrigues, Teresa; Bermejo, Marival; González-Álvarez, Isabel; Nguyen-Hai, Nam; Cabrera-Pérez, Miguel Ángel; Le-Thi-Thu, Huong

    2016-02-01

    In many absorption, distribution, metabolism, and excretion (ADME) modeling problems, imbalanced data could negatively affect classification performance of machine learning algorithms. Solutions for handling imbalanced dataset have been proposed, but their application for ADME modeling tasks is underexplored. In this paper, various strategies including cost-sensitive learning and resampling methods were studied to tackle the moderate imbalance problem of a large Caco-2 cell permeability database. Simple physicochemical molecular descriptors were utilized for data modeling. Support vector machine classifiers were constructed and compared using multiple comparison tests. Results showed that the models developed on the basis of resampling strategies displayed better performance than the cost-sensitive classification models, especially in the case of oversampling data where misclassification rates for minority class have values of 0.11 and 0.14 for training and test set, respectively. A consensus model with enhanced applicability domain was subsequently constructed and showed improved performance. This model was used to predict a set of randomly selected high-permeability reference drugs according to the biopharmaceutics classification system. Overall, this study provides a comparison of numerous rebalancing strategies and displays the effectiveness of oversampling methods to deal with imbalanced permeability data problems.

  9. Tackling Millennium Development Goals (MDGs) 4 and 5: The National Health Insurance Scheme (NHIS) Approach in Nigeria.

    PubMed

    Mohammed, Shafiu; Dong, Hengjin

    2012-03-07

    Developing countries are devising various strategies and mechanisms to accelerate their speed towards the Millennium Development Goals (MDGs) by 2015. In Nigeria, different approaches have been used to address the tackling of health-related MDGs. One creative approach has been the implementation of the NHIS Maternal and Child Health (NHIS-MCH) Project. The project aims to speed up the achievement of MDGs 4 and 5 (reducing child mortality and improving maternal health) in the country. Little is known about the NHIS-MCH Project's design and health insurance coverage activities. Project planning and monitoring could be hampered by lack of technical and managerial skills of health insurance most especially at middle and local levels. Challenging debates continue to emanate on the project's sustainability.

  10. NASA ROVER, Tackling Citizen Science With Grand Challenges and Everyday Problems

    NASA Technical Reports Server (NTRS)

    Crecelius, Sarah; Chambers, Lin; Rogerson, Tina

    2015-01-01

    ROVER is the Citizen Science arm of the NASA Clouds and the Earth's Radiant Energy System (CERES) Students' Cloud Observations On-Line (S'COOL) Project. Since 2007, participants around the world have been making and reporting ground truth observations of clouds to assist in the validation of the NASA CERES satellite instrument. NASA scientists are very interested in learning how clouds affect our atmosphere, weather, and climate (relating to climate change). It is the clouds, in part, that affect the overall temperature and energy balance of the Earth. The more we know about clouds, the more we will know about our Earth as a system and citizen scientists are an important piece of that puzzle! As a ROVER cloud observer, all participants follow simple online tutorials to collect data on cloud type, height, cover and related conditions. Observations are sent to NASA to be matched to similar information obtained from satellites and sent back to participants for comparison and analysis. The supporting ROVER website houses a searchable database archiving all participant reports and matching satellite data. By involving Citizen Scientists in cloud observations and reporting we can gain a valuable set of data that would have been previously unavailable to science teams due to funding, manpower, and resource limitations or would have taken an unreasonable amount of time to collect. Reports from a wide range of Citizen Scientist locations are helpful to assess the satellite data under different conditions. With nothing more than their eyes and an internet connection participants provide a different perspective and analysis of clouds, adding to a more complete picture of what's happening in the atmosphere in which we live.

  11. Tackling of unhealthy diets, physical inactivity, and obesity: health effects and cost-effectiveness.

    PubMed

    Cecchini, Michele; Sassi, Franco; Lauer, Jeremy A; Lee, Yong Y; Guajardo-Barron, Veronica; Chisholm, Daniel

    2010-11-20

    The obesity epidemic is spreading to low-income and middle-income countries as a result of new dietary habits and sedentary ways of life, fuelling chronic diseases and premature mortality. In this report we present an assessment of public health strategies designed to tackle behavioural risk factors for chronic diseases that are closely linked with obesity, including aspects of diet and physical inactivity, in Brazil, China, India, Mexico, Russia, and South Africa. England was included for comparative purposes. Several population-based prevention policies can be expected to generate substantial health gains while entirely or largely paying for themselves through future reductions of health-care expenditures. These strategies include health information and communication strategies that improve population awareness about the benefits of healthy eating and physical activity; fiscal measures that increase the price of unhealthy food content or reduce the cost of healthy foods rich in fibre; and regulatory measures that improve nutritional information or restrict the marketing of unhealthy foods to children. A package of measures for the prevention of chronic diseases would deliver substantial health gains, with a very favourable cost-effectiveness profile. Copyright © 2010 Elsevier Ltd. All rights reserved.

  12. Can the sociology of social problems help us to understand and manage 'lifestyle drift'?

    PubMed

    Carey, Gemma; Malbon, Eleanor; Crammond, Brad; Pescud, Melanie; Baker, Philip

    2017-08-01

    Lifestyle drift is increasingly seen as a barrier to broad action on the social determinants of health. The term is currently used in the population health literature to describe how broad policy initiatives for tackling inequalities in health that start off with social determinants (upstream) approach drift downstream to largely individual lifestyle factors, as well as the general trend of investing a the individual level. Lifestyle drift occurs despite the on-going efforts of public health advocates, such as anti-obesity campaigners, to draw attention to the social factors which shape health behavior and outcomes. In this article, we explore whether the sociology of social problems can help understand lifestyle drift in the context of obesity. Specifically, we apply Jamrozik and Nocella's residualist conversion model to the problem of obesity in order to explore whether such an approach can provide greater insight into the processes that underpin lifestyle drift and inform our attempts to mitigate it. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  13. Improving psychosexual knowledge in adolescents with autism spectrum disorder: pilot of the tackling teenage training program.

    PubMed

    Dekker, Linda P; van der Vegt, Esther J M; Visser, Kirsten; Tick, Nouchka; Boudesteijn, Frieda; Verhulst, Frank C; Maras, Athanasios; Greaves-Lord, Kirstin

    2015-06-01

    Previous studies have shown that psychosexual functioning in adolescents with autism spectrum disorder (ASD) is hampered and emphasize the need for a specialized training program tailored to their needs. Therefore, an individual training program was developed; the Tackling Teenage Training (TTT) program. The current pilot study systematically evaluated whether psychosexual knowledge increased after taking part in the TTT program, using a pre- and post-training design in 30 adolescents with ASD (77 % male, mean age = 14.80 years, mean intelligence = 96.96). Psychosexual knowledge increased significantly (pre-training total score: M = 25.74, SD = 6.20; post-training total score: M = 33.52 (SD = 2.78); F(1,29) = 65.20, p < .001). The TTT program may be useful to improve psychosexual knowledge and functioning in adolescents with ASD, yet these findings are preliminary, and a more elaborate controlled trial is needed.

  14. Tackling the wider social determinants of health and health inequalities: evidence from systematic reviews

    PubMed Central

    Gibson, M; Sowden, A; Wright, K; Whitehead, M; Petticrew, M

    2010-01-01

    Background There is increasing pressure to tackle the wider social determinants of health through the implementation of appropriate interventions. However, turning these demands for better evidence about interventions around the social determinants of health into action requires identifying what we already know and highlighting areas for further development. Methods Systematic review methodology was used to identify systematic reviews (from 2000 to 2007, developed countries only) that described the health effects of any intervention based on the wider social determinants of health: water and sanitation, agriculture and food, access to health and social care services, unemployment and welfare, working conditions, housing and living environment, education, and transport. Results Thirty systematic reviews were identified. Generally, the effects of interventions on health inequalities were unclear. However, there is suggestive systematic review evidence that certain categories of intervention may impact positively on inequalities or on the health of specific disadvantaged groups, particularly interventions in the fields of housing and the work environment. Conclusion Intervention studies that address inequalities in health are a priority area for future public health research. PMID:19692738

  15. Program effectiveness of a Restorative Whole-school Approach for tackling school bullying in Hong Kong.

    PubMed

    Wong, Dennis S W; Cheng, Christopher H K; Ngan, Raymond M H; Ma, Stephen K

    2011-09-01

    With bullying in schools high on policy makers' agendas, researchers are looking for effective strategies to tackle its disruptive effects. The present study sets out to address this issue. First, the prevalence of bullying is examined in Hong Kong High Schools, and second, the effectiveness of a Restorative Whole-school Approach (RWsA) in reducing bullying is examined in a quasi-experimental design. The RWsA emphasizes the setting up of restorative goals, clear instructions, team building, and good relationships among students, parents, and teachers. Over the course of 2 years, and across four schools, the effectiveness of this program was observed by comparing an intervention group with a partial intervention group (which did not receive the full treatment) and a control group (which received no treatment whatsoever). The group that received the RWsA treatment exhibited a significant reduction of bullying, higher empathic attitudes, and higher self-esteem in comparison to the partial intervention and the control group.

  16. Farm Crisis Response: Extension and Research Activities in the North Central Region.

    ERIC Educational Resources Information Center

    Lasley, Paul, Comp.; And Others

    The 12 states comprising the North Central Region have been affected in similar ways by the farm crisis of the 1980s. Statewide surveys show sizeable proportions of farm operations that are experiencing moderately high levels of financial stress. The problems caused by chronic stress on family structure and functioning, the loss of mainstreet…

  17. Community and Conversation: Tackling Beginning Teacher Doubt and Disillusion

    ERIC Educational Resources Information Center

    Shann, Steve; Germantse, Hannah; Pittard, Libby; Cunneen, Rachel

    2014-01-01

    Margaret Somerville has suggested that a new methodology of postmodern emergence might allow researchers to disrupt the taken-for-granted and provide fresh insight into familiar problems. One such familiar problem is the doubt and disillusion many early-career teachers experience, both during their teacher education and in their first years.…

  18. Mob justice in Tanzania: a medico-social problem.

    PubMed

    Ng'walali, Paul M; Kitinya, James N

    2006-03-01

    To investigate the magnitude of mob justice and associated factors. Mob justice is a social and public health problem that has grown in Tanzania in recent decades that has negative effects on social and health of the country, communities, and families. A four-year autopsy study was conducted at the Department of Pathology, MUCHS. Information on the cases was obtained from police, the relatives, friends and other witnesses if available. 1,249 persons were killed by mobs in Dar es Salaam during the period of 5 years (2000-2004). The alleged offense ranged from a serious crime like theft or murder to a mere violation of local customs or religious beliefs. The mode of the killings were mostly burning (48.11%) and stoning (49.96%). Other modes accounted for only 3.0% of the cases. The pattern of injuries ranged from skull and other skeletal fractures to viscera rupture. MJ is a social, legal and public health problem in Tanzania that needs immediate attention. Unemployment of youth and perceived economic inequalities should be addressed. As long as the judicial system doesn't work and corruption is not punished, people will continue to organize their own trials and judge their suspects in the street. These must be tackled in order to reduce the growing incidences of mob justice, hence saving life. It must be ensured that criminals do not violate the freedom, dignity and respect of each and every human or member of the society.

  19. Learning automata-based solutions to the nonlinear fractional knapsack problem with applications to optimal resource allocation.

    PubMed

    Granmo, Ole-Christoffer; Oommen, B John; Myrer, Svein Arild; Olsen, Morten Goodwin

    2007-02-01

    This paper considers the nonlinear fractional knapsack problem and demonstrates how its solution can be effectively applied to two resource allocation problems dealing with the World Wide Web. The novel solution involves a "team" of deterministic learning automata (LA). The first real-life problem relates to resource allocation in web monitoring so as to "optimize" information discovery when the polling capacity is constrained. The disadvantages of the currently reported solutions are explained in this paper. The second problem concerns allocating limited sampling resources in a "real-time" manner with the purpose of estimating multiple binomial proportions. This is the scenario encountered when the user has to evaluate multiple web sites by accessing a limited number of web pages, and the proportions of interest are the fraction of each web site that is successfully validated by an HTML validator. Using the general LA paradigm to tackle both of the real-life problems, the proposed scheme improves a current solution in an online manner through a series of informed guesses that move toward the optimal solution. At the heart of the scheme, a team of deterministic LA performs a controlled random walk on a discretized solution space. Comprehensive experimental results demonstrate that the discretization resolution determines the precision of the scheme, and that for a given precision, the current solution (to both problems) is consistently improved until a nearly optimal solution is found--even for switching environments. Thus, the scheme, while being novel to the entire field of LA, also efficiently handles a class of resource allocation problems previously not addressed in the literature.

  20. Antimicrobial Peptides: A Promising Therapeutic Strategy in Tackling Antimicrobial Resistance.

    PubMed

    Nuti, Ramya; Goud, Nerella S; Saraswati, A Prasanth; Alvala, Ravi; Alvala, Mallika

    2017-01-01

    Antimicrobial resistance (AMR) has posed a serious threat to global public health and it requires immediate action, preferably long term. Current drug therapies have failed to curb this menace due to the ability of microbes to circumvent the mechanisms through which the drugs act. From the drug discovery point of view, the majority of drugs currently employed for antimicrobial therapy are small molecules. Recent trends reveal a surge in the use of peptides as drug candidates as they offer remarkable advantages over small molecules. Newer synthetic strategies like organometalic complexes, Peptide-polymer conjugates, solid phase, liquid phase and recombinant DNA technology encouraging the use of peptides as therapeutic agents with a host of chemical functions, and tailored for specific applications. In the last decade, many peptide based drugs have been successfully approved by the Food and Drug Administration (FDA). This success can be attributed to their high specificity, selectivity and efficacy, high penetrability into the tissues, less immunogenicity and less tissue accumulation. Considering the enormity of AMR, the use of Antimicrobial Peptides (AMPs) can be a viable alternative to current therapeutics strategies. AMPs are naturally abundant allowing synthetic chemists to develop semi-synthetics peptide molecules. AMPs have a broad spectrum of activity towards microbes and they possess the ability to bypass the resistance induction mechanisms of microbes. The present review focuses on the potential applications of AMPs against various microbial disorders and their future prospects. Several resistance mechanisms and their strategies have also been discussed to highlight the importance in the current scenario. Breakthroughs in AMP designing, peptide synthesis and biotechnology have shown promise in tackling this challenge and has revived the interest of using AMPs as an important weapon in fighting AMR. Copyright© Bentham Science Publishers; For any queries

  1. Injury risk and a tackle ban in youth Rugby Union: reviewing the evidence and searching for targeted, effective interventions. A critical review.

    PubMed

    Tucker, Ross; Raftery, Martin; Verhagen, Evert

    2016-08-01

    It has recently been proposed that the tackle, an integral part of Rugby Union, be banned in school rugby, as a means to reduce the risk of injury. This proposal held that harmful contact should be removed in response to what was termed an unacceptably high-injury risk. Such a ban would represent a significant intervention that could change the nature of Rugby Union. As such, the basis and rationale for such a ban is worthy of critical evaluation. This review aims to describe the research on which such a ban is proposed. It does so through an assessment (identification), estimation (understanding of the magnitude and occurrence) and evaluation (determining acceptability) of the risk before decisions can be made about implementing any risk mitigation strategies. The body of literature describing injury risk, particularly among youths, is indeed thin and fraught with methodological differences that makes definitive conclusions impossible. We describe these, and their implications, arguing that the complete ban on the tackle may be unnecessary in young children, in whom injury risk may not be as high as is often argued, but also that it may have detrimental consequences. Finally, we propose alternative strategies and research questions which must be pursued to effectively reduce risk without creating unintended consequences or changing the nature of the sport. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  2. Engineering and control of biological systems: A new way to tackle complex diseases.

    PubMed

    Menolascina, Filippo; Siciliano, Velia; di Bernardo, Diego

    2012-07-16

    The ongoing merge between engineering and biology has contributed to the emerging field of synthetic biology. The defining features of this new discipline are abstraction and standardisation of biological parts, decoupling between parts to prevent undesired cross-talking, and the application of quantitative modelling of synthetic genetic circuits in order to guide their design. Most of the efforts in the field of synthetic biology in the last decade have been devoted to the design and development of functional gene circuits in prokaryotes and unicellular eukaryotes. Researchers have used synthetic biology not only to engineer new functions in the cell, but also to build simpler models of endogenous gene regulatory networks to gain knowledge of the "rules" governing their wiring diagram. However, the need for innovative approaches to study and modify complex signalling and regulatory networks in mammalian cells and multicellular organisms has prompted advances of synthetic biology also in these species, thus contributing to develop innovative ways to tackle human diseases. In this work, we will review the latest progress in synthetic biology and the most significant developments achieved so far, both in unicellular and multicellular organisms, with emphasis on human health. Copyright © 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

  3. Performance of mixed formulations for the particle finite element method in soil mechanics problems

    NASA Astrophysics Data System (ADS)

    Monforte, Lluís; Carbonell, Josep Maria; Arroyo, Marcos; Gens, Antonio

    2017-07-01

    This paper presents a computational framework for the numerical analysis of fluid-saturated porous media at large strains. The proposal relies, on one hand, on the particle finite element method (PFEM), known for its capability to tackle large deformations and rapid changing boundaries, and, on the other hand, on constitutive descriptions well established in current geotechnical analyses (Darcy's law; Modified Cam Clay; Houlsby hyperelasticity). An important feature of this kind of problem is that incompressibility may arise either from undrained conditions or as a consequence of material behaviour; incompressibility may lead to volumetric locking of the low-order elements that are typically used in PFEM. In this work, two different three-field mixed formulations for the coupled hydromechanical problem are presented, in which either the effective pressure or the Jacobian are considered as nodal variables, in addition to the solid skeleton displacement and water pressure. Additionally, several mixed formulations are described for the simplified single-phase problem due to its formal similitude to the poromechanical case and its relevance in geotechnics, since it may approximate the saturated soil behaviour under undrained conditions. In order to use equal-order interpolants in displacements and scalar fields, stabilization techniques are used in the mass conservation equation of the biphasic medium and in the rest of scalar equations. Finally, all mixed formulations are assessed in some benchmark problems and their performances are compared. It is found that mixed formulations that have the Jacobian as a nodal variable perform better.

  4. Time to tackle clonorchiasis in China

    PubMed Central

    2013-01-01

    Recent publication of the global epidemiology of clonorchiasis and its relationship with cholangiocarcinoma in the journal of Infectious Diseases of Poverty has stressed the importance of Clonorchis sinensis infection. To further demonstrate its threat on public health, especially in China, comparisons between clonorchiasis and hepatitis B are made in terms of epidemiology, clinical symptoms and carcinogenicity, disability, as well as changing trends. Furthermore, major problems and prioritized researches are argued, from basic biology to intervention. Imbalance between the majority of infected population and the minority of researches in China urges for more work from Chinese scientists and international cooperation. PMID:23849773

  5. Deliberative Mapping of options for tackling climate change: Citizens and specialists 'open up' appraisal of geoengineering.

    PubMed

    Bellamy, Rob; Chilvers, Jason; Vaughan, Naomi E

    2016-04-01

    Appraisals of deliberate, large-scale interventions in the earth's climate system, known collectively as 'geoengineering', have largely taken the form of narrowly framed and exclusive expert analyses that prematurely 'close down' upon particular proposals. Here, we present the findings from the first 'upstream' appraisal of geoengineering to deliberately 'open up' to a broader diversity of framings, knowledges and future pathways. We report on the citizen strand of an innovative analytic-deliberative participatory appraisal process called Deliberative Mapping. A select but diverse group of sociodemographically representative citizens from Norfolk (United Kingdom) were engaged in a deliberative multi-criteria appraisal of geoengineering proposals relative to other options for tackling climate change, in parallel to symmetrical appraisals by diverse experts and stakeholders. Despite seeking to map divergent perspectives, a remarkably consistent view of option performance emerged across both the citizens' and the specialists' deliberations, where geoengineering proposals were outperformed by mitigation alternatives. © The Author(s) 2014.

  6. Benchmarking progress in tackling the challenges of intellectual property, and access to medicines in developing countries.

    PubMed Central

    Musungu, Sisule F.

    2006-01-01

    The impact of intellectual property protection in the pharmaceutical sector on developing countries has been a central issue in the fierce debate during the past 10 years in a number of international fora, particularly the World Trade Organization (WTO) and WHO. The debate centres on whether the intellectual property system is: (1) providing sufficient incentives for research and development into medicines for diseases that disproportionately affect developing countries; and (2) restricting access to existing medicines for these countries. The Doha Declaration was adopted at WTO in 2001 and the Commission on Intellectual Property, Innovation and Public Health was established at WHO in 2004, but their respective contributions to tackling intellectual property-related challenges are disputed. Objective parameters are needed to measure whether a particular series of actions, events, decisions or processes contribute to progress in this area. This article proposes six possible benchmarks for intellectual property-related challenges with regard to the development of medicines and ensuring access to medicines in developing countries. PMID:16710545

  7. Solving optimization problems on computational grids.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wright, S. J.; Mathematics and Computer Science

    2001-05-01

    infrastructure need to solve these problems on computational grids. This article describes some of the results we have obtained during the first three years of the metaneos project. Our efforts have led to development of the runtime support library MW for implementing algorithms with master-worker control structure on Condor platforms. This work is discussed here, along with work on algorithms and codes for integer linear programming, the quadratic assignment problem, and stochastic linear programmming. Our experiences in the metaneos project have shown that cheap, powerful computational grids can be used to tackle large optimization problems of various types. In an industrial or commercial setting, the results demonstrate that one may not have to buy powerful computational servers to solve many of the large problems arising in areas such as scheduling, portfolio optimization, or logistics; the idle time on employee workstations (or, at worst, an investment in a modest cluster of PCs) may do the job. For the optimization research community, our results motivate further work on parallel, grid-enabled algorithms for solving very large problems of other types. The fact that very large problems can be solved cheaply allows researchers to better understand issues of 'practical' complexity and of the role of heuristics.« less

  8. Tackling Missing Data in Community Health Studies Using Additive LS-SVM Classifier.

    PubMed

    Wang, Guanjin; Deng, Zhaohong; Choi, Kup-Sze

    2018-03-01

    Missing data is a common issue in community health and epidemiological studies. Direct removal of samples with missing data can lead to reduced sample size and information bias, which deteriorates the significance of the results. While data imputation methods are available to deal with missing data, they are limited in performance and could introduce noises into the dataset. Instead of data imputation, a novel method based on additive least square support vector machine (LS-SVM) is proposed in this paper for predictive modeling when the input features of the model contain missing data. The method also determines simultaneously the influence of the features with missing values on the classification accuracy using the fast leave-one-out cross-validation strategy. The performance of the method is evaluated by applying it to predict the quality of life (QOL) of elderly people using health data collected in the community. The dataset involves demographics, socioeconomic status, health history, and the outcomes of health assessments of 444 community-dwelling elderly people, with 5% to 60% of data missing in some of the input features. The QOL is measured using a standard questionnaire of the World Health Organization. Results show that the proposed method outperforms four conventional methods for handling missing data-case deletion, feature deletion, mean imputation, and K-nearest neighbor imputation, with the average QOL prediction accuracy reaching 0.7418. It is potentially a promising technique for tackling missing data in community health research and other applications.

  9. Make induction day more effective - add a few problems.

    PubMed

    Mitchell, H E; Laidlaw, J M

    1999-06-01

    Induction courses are important to introduce Pre-Registration House Officers (PRHOs) to their new place of work. Traditionally, such programmes employ lectures, small group discussion and demonstrations. They let PRHOs meet members of various hospital disciplines and services. Since 1991, an interactive induction programme has been held each August for new PRHOs in the Eastern Region of Scotland taking up posts in Dundee Teaching Hospitals NHS Trust. Feedback from participants allows the course to be refined each year. In 1995, three paper-based patient management problems (PMPs) were included in the induction programme. Response was favourable. Most of the participants (82%) suggested the PMPs should be used again, but that more time should be allocated to enable them to tackle the problems. By August 1996, we aimed to provide a relevant and interactive programme that encouraged PRHOs to make immediate use of hospital resources. Two PMPs, in print format described likely case histories, with tasks that mirrored the junior doctors' forthcoming responsibilities. Healthcare team members and laboratory staff provided support as did study boards displaying written sheets of relevant clinical information. In the subsequent evaluation, the PMP component was rated highly by participants. They effectively triggered PRHOs to interact with hospital staff. We conclude that PMPs provide a valuable learning experience for junior doctors and are a useful addition to an induction day programme. We plan to refine and increase the use of PMPs in undergraduate and postgraduate settings.

  10. The Fiscal Year 1993 Bush Budget: Still Not Tackling the Nation's Problems.

    ERIC Educational Resources Information Center

    Greenstein, Robert; Leonard, Paul A.

    On January 29, 1992, the Bush Administration unveiled its fiscal year 1993 budget. An examination of the budget reveals a substantial gap between the administration's rhetoric concerning the budget and what the budget actually contains. An analysis reveals a budget that continues to give priority to defense over domestic spending, one that favors…

  11. An Ultrahydrophobic Fluorous Metal-Organic Framework Derived Recyclable Composite as a Promising Platform to Tackle Marine Oil Spills.

    PubMed

    Mukherjee, Soumya; Kansara, Ankit M; Saha, Debasis; Gonnade, Rajesh; Mullangi, Dinesh; Manna, Biplab; Desai, Aamod V; Thorat, Shridhar H; Singh, Puyam S; Mukherjee, Arnab; Ghosh, Sujit K

    2016-07-25

    Derived from a strategically chosen hexafluorinated dicarboxylate linker aimed at the designed synthesis of a superhydrophobic metal-organic framework (MOF), the fluorine-rich nanospace of a water-stable MOF (UHMOF-100) exhibits excellent water-repellent features. It registered the highest water contact angle (≈176°) in the MOF domain, marking the first example of an ultrahydrophobic MOF. Various experimental and theoretical studies reinforce its distinctive water-repellent characteristics, and the conjugation of superoleophilicity and unparalleled hydrophobicity of a MOF material has been coherently exploited to achieve real-time oil/water separation in recyclable membrane form, with significant absorption capacity performance. This is also the first report of an oil/water separating fluorinated ultrahydrophobic MOF-based membrane material, with potential promise for tackling marine oil spillages. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Binary optimization for source localization in the inverse problem of ECG.

    PubMed

    Potyagaylo, Danila; Cortés, Elisenda Gil; Schulze, Walther H W; Dössel, Olaf

    2014-09-01

    The goal of ECG-imaging (ECGI) is to reconstruct heart electrical activity from body surface potential maps. The problem is ill-posed, which means that it is extremely sensitive to measurement and modeling errors. The most commonly used method to tackle this obstacle is Tikhonov regularization, which consists in converting the original problem into a well-posed one by adding a penalty term. The method, despite all its practical advantages, has however a serious drawback: The obtained solution is often over-smoothed, which can hinder precise clinical diagnosis and treatment planning. In this paper, we apply a binary optimization approach to the transmembrane voltage (TMV)-based problem. For this, we assume the TMV to take two possible values according to a heart abnormality under consideration. In this work, we investigate the localization of simulated ischemic areas and ectopic foci and one clinical infarction case. This affects only the choice of the binary values, while the core of the algorithms remains the same, making the approximation easily adjustable to the application needs. Two methods, a hybrid metaheuristic approach and the difference of convex functions (DC), algorithm were tested. For this purpose, we performed realistic heart simulations for a complex thorax model and applied the proposed techniques to the obtained ECG signals. Both methods enabled localization of the areas of interest, hence showing their potential for application in ECGI. For the metaheuristic algorithm, it was necessary to subdivide the heart into regions in order to obtain a stable solution unsusceptible to the errors, while the analytical DC scheme can be efficiently applied for higher dimensional problems. With the DC method, we also successfully reconstructed the activation pattern and origin of a simulated extrasystole. In addition, the DC algorithm enables iterative adjustment of binary values ensuring robust performance.

  13. Serious game development as a strategy for health promotion and tackling childhood obesity 1

    PubMed Central

    Dias, Jéssica David; Mekaro, Marcelo Shinyu; Cheng Lu, Jennifer Kaon; Otsuka, Joice Lee; Fonseca, Luciana Mara Monti; Zem-Mascarenhas, Silvia Helena

    2016-01-01

    ABSTRACT Objectives: to develop and assess a serious game on healthy eating and physical activity to promote health and tackle childhood obesity. Method: a descriptive, applied and methodological study.For the development of the game, the following steps were taken: conceptualization, pre-production with the development of the game documentation, prototyping, production and assessment of thecomputer and health experts. Results: a prototype has been developed up to beta version. The game was positively assessed both in terms of gameplay and mechanics, and in relation to the content presented, standing out as a powerful strategy for health promotion. The information from the assessment phase contributed to the settings in the software in order to make it available in the future for the target population of this research. The greatest advantage of the proposed game is the fact that it is an open educational resource. Conclusions: the expert assessments showed that the game has great educational potential and it is considered suitable for future application to the target audience.The serious game can become a technological teaching resource available for use in schools and health facilities, and can also be reused for the production of other educational games by accessing its source code. PMID:27533268

  14. Deliberative Mapping of options for tackling climate change: Citizens and specialists ‘open up’ appraisal of geoengineering

    PubMed Central

    Bellamy, Rob; Chilvers, Jason; Vaughan, Naomi E.

    2014-01-01

    Appraisals of deliberate, large-scale interventions in the earth’s climate system, known collectively as ‘geoengineering’, have largely taken the form of narrowly framed and exclusive expert analyses that prematurely ‘close down’ upon particular proposals. Here, we present the findings from the first ‘upstream’ appraisal of geoengineering to deliberately ‘open up’ to a broader diversity of framings, knowledges and future pathways. We report on the citizen strand of an innovative analytic–deliberative participatory appraisal process called Deliberative Mapping. A select but diverse group of sociodemographically representative citizens from Norfolk (United Kingdom) were engaged in a deliberative multi-criteria appraisal of geoengineering proposals relative to other options for tackling climate change, in parallel to symmetrical appraisals by diverse experts and stakeholders. Despite seeking to map divergent perspectives, a remarkably consistent view of option performance emerged across both the citizens’ and the specialists’ deliberations, where geoengineering proposals were outperformed by mitigation alternatives. PMID:25224904

  15. Tackling community integration in mental health home visit integration in Finland.

    PubMed

    Raitakari, Suvi; Haahtela, Riikka; Juhila, Kirsi

    2016-09-01

    Integration - and its synonym inclusion - is emphasised in the western welfare states and in the European Union in particular. Integration is also a central topic in the social sciences and in current mental health and homelessness research and practice. As mental healthcare has shifted from psychiatric hospitals to the community, it has inevitably become involved with housing and integration issues. This article explores how community integration is understood and tackled in mental health floating support services (FSSs) and, more precisely, in service user-practitioner home visit interaction. The aim, through shedding light on how the idea of integration is present and discussed in front-line mental health practices, is to offer a 'template' on how we might, in a systematic and reflective way, develop community integration research and practice. The analysis is based on ethnomethodological and micro-sociological interaction research. The research settings are two FSSs located in a large Finnish city. The data contain 24 audio-recorded and transcribed home visits conducted in 2011 and 2012 with 16 different service users. The study shows how the participants in service user-practitioner interaction give meaning to community integration and make decisions about how it should (or should not) be enhanced in each individual case. This activity is called community integration work in action. Community integration work in action is based on various dimensions of integration: getting out of the house, participating in group activities and getting along with those involved in one's life and working life. Additionally, the analysis demonstrates how community integration work is accomplished by discursive devices (resistance, positioning, excuses and justifications, delicacy and advice-giving). The article concludes that community integration is about interaction: it is not only service users' individual challenge but also a social challenge, our challenge. © 2015 John

  16. [Social and organizational innovation to tackle the challenge of integrated care of the chronically ill].

    PubMed

    Nuño-Solinís, Roberto

    2014-01-01

    The increase in life expectancy, coupled with other factors, has led to an increase in the prevalence of chronic diseases and multiple morbidity. This has led to the need to develop new health and social care models, which will allow managing these efficiently and in a sustainable manner. In particular, there seems to be consensus on the need to move towards integrated, patient-centered, and more proactive care. Thus, in recent years, chronic care models have been developed at international, national and regional level, as well as introducing strategies to tackle the challenge of chronic illness. However, the implementation of actions facilitating the change towards this new model of care does not seem to be an easy task. This paper presents some of the strategic lines and initiatives carried out by the Department of Health of the Basque Government. These actions can be described within a social and organizational innovation framework, as a means for effective implementation of interventions and strategies that shape the model required for the improved care of chronic illnesses within a universal and tax-funded health system. Copyright © 2013 Elsevier España, S.L. All rights reserved.

  17. Building Beautiful Minds: Teaching Through Movies to Tackle Stigma in Psychology Students in the UAE.

    PubMed

    Petkari, Eleni

    2017-12-01

    The use of movie-based educational interventions has been used widely and is considered an effective method aiming at changing the stigmatizing attitudes of future mental health professionals. The purpose of this study was to examine the effectiveness of a 10-week intervention that combined movies and related discussions in a sample of 26 psychology students in the United Arab Emirates, where the opportunities for real contact with patients with mental illness are limited. By means of mixed methods approach, students were assessed at two time points by the Opening Minds Stigma Scale for Health Care Providers [OMS-HC] (T1-T2) and by qualitative questions only at the end of the intervention (T2). The results corroborated changes to some of the students' attitudes, namely agency, compassion, and proximity, but did not prove a general attitudinal change. Additionally, students acknowledged the benefit obtained by their participation with regard to their learning experience, pointing out the importance of combining theory with practical examples of mental illness for spreading awareness and tackling stigma. The results are discussed in the light of their importance for the United Arab Emirates educational context.

  18. Beyond CO2 - Tackling the full greenhouse gas budget of a sub-alpine forest ecosystem

    NASA Astrophysics Data System (ADS)

    Burri, Susanne; Merbold, Lutz; Meier, Philip; Eugster, Werner; Hörtnagl, Lukas; Buchmann, Nina

    2017-04-01

    In order to tackle the full greenhouse gas (GHG) budgets of forest ecosystems, it is desirable but challenging to quantify the three major GHGs, i.e. CO2, CH4 and N2O simultaneously in-situ. At the long-term forest research site Davos (Candidate Class I Ecosystem Station within the Integrated Carbon Observation System - ICOS), we have recently installed a state-of-the-art measuring system simultaneously to observe the three GHGs on a high temporal resolution and both within and above the forest canopy. Thereby, we combine above-canopy eddy covariance flux measurements and forest floor chamber flux measurements (using five custom-made fully automated chambers). Both systems are connected to a quantum cascade laser absorption spectrometer (QCL, Aerodyne) and measurements are switched between three hours of above-canopy and one hour of forest floor GHG flux measurements. Using this approach, we will be able to study the full GHG budget as well as the dynamics of the individual fluxes on two vertical levels within the forest using a single instrument. The first results presented here will highlight the suitability of this promising tool for quantifying the full GHG budget of forest ecosystems.

  19. Shift Work and Health: Current Problems and Preventive Actions

    PubMed Central

    2010-01-01

    The paper gives an overview of the problems to be tackled nowadays by occupational health with regards to shift work as well as the main guidelines at organizational and medical levels on how to protect workers' health and well-being. Working time organization is becoming a key factor on account of new technologies, market globalization, economic competition, and extension of social services to general populations, all of which involve more and more people in continuous assistance and control of work processes over the 24 hours in a day. The large increase of epidemiological and clinical studies on this issue document the severity of this risk factor on human health and well being, at both social and psychophysical levels, starting from a disruption of biological circadian rhythms and sleep/wake cycle and ending in several psychosomatic troubles and disorders, likely also including cancer, and extending to impairment of performance efficiency as well as family and social life. Appropriate interventions on the organization of shift schedules according to ergonomic criteria and careful health surveillance and social support for shift workers are important preventive and corrective measures that allow people to keep working without significant health impairment. PMID:22953171

  20. Milne, a routine for the numerical solution of Milne's problem

    NASA Astrophysics Data System (ADS)

    Rawat, Ajay; Mohankumar, N.

    2010-11-01

    The routine Milne provides accurate numerical values for the classical Milne's problem of neutron transport for the planar one speed and isotropic scattering case. The solution is based on the Case eigen-function formalism. The relevant X functions are evaluated accurately by the Double Exponential quadrature. The calculated quantities are the extrapolation distance and the scalar and the angular fluxes. Also, the H function needed in astrophysical calculations is evaluated as a byproduct. Program summaryProgram title: Milne Catalogue identifier: AEGS_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEGS_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 701 No. of bytes in distributed program, including test data, etc.: 6845 Distribution format: tar.gz Programming language: Fortran 77 Computer: PC under Linux or Windows Operating system: Ubuntu 8.04 (Kernel version 2.6.24-16-generic), Windows-XP Classification: 4.11, 21.1, 21.2 Nature of problem: The X functions are integral expressions. The convergence of these regular and Cauchy Principal Value integrals are impaired by the singularities of the integrand in the complex plane. The DE quadrature scheme tackles these singularities in a robust manner compared to the standard Gauss quadrature. Running time: The test included in the distribution takes a few seconds to run.

  1. A uniform object-oriented solution to the eigenvalue problem for real symmetric and Hermitian matrices

    NASA Astrophysics Data System (ADS)

    Castro, María Eugenia; Díaz, Javier; Muñoz-Caro, Camelia; Niño, Alfonso

    2011-09-01

    and conquer, can be used to factorize the matrices in order to apply a parallel computing approach. However, it is still interesting to have a core procedure able to tackle the computation of eigenvalues and eigenvectors once the matrix has been factorized to pieces of enough small size. Several available software packages, such as LAPACK, tackled this problem under the traditional imperative programming paradigm. In order to ease the modelling of complex quantum mechanical models it could be interesting to apply an object-oriented approach to the treatment of the eigenproblem. This approach offers the advantage of a single, uniform treatment for the real symmetric and Hermitian cases. Solution method: To reach the above goals, we have developed a system of classes: SHMatrix. SHMatrix is composed by an abstract base class and two descendant classes, one for real symmetric matrices and the other for the Hermitian case. The object-oriented characteristics of inheritance and polymorphism allows handling both cases using a single reference of the base class. The basic computing strategy applied in SHMatrix allows computing subsets of eigenvalues and (optionally) eigenvectors. The tests performed show that SHMatrix is competitive, and more efficient for large matrices, than the equivalent routines of the LAPACK package. Running time: The examples included in the distribution take only a couple of seconds to run.

  2. Big questions come in bundles, hence they should be tackled systemically.

    PubMed

    Bunge, Mario

    2014-01-01

    A big problem is, by definition, one involving either multiple traits of a thing, or a collection of things. Because such problems are systemic or global rather than local or sectoral, they call for a systemic approach, and often a multidisciplinary one as well. Just think of individual and public health problems, or of income inequality, gender discrimination, housing, environmental, or political participation issues. All of them are inter-related, so that focusing on one of them at a time is bound to produce either short-term solutions or utter failure. This is also why single-issue political movements are bound to fail. In other words, big problems are systemic and must, therefore be approached systemically--though with the provisos that systemism must not be confused with holism and that synthesis complements analysis instead of replacing it.

  3. The agency problem and medical acting: an example of applying economic theory to medical ethics.

    PubMed

    Langer, Andreas; Schröder-Bäck, Peter; Brink, Alexander; Eurich, Johannes

    2009-03-01

    In this article, the authors attempt to build a bridge between economic theory and medical ethics to offer a new perspective to tackle ethical challenges in the physician-patient encounter. They apply elements of new institutional economics to the ethically relevant dimensions of the physician-patient relationship in a descriptive heuristic sense. The principal-agent theory can be used to analytically grasp existing action problems in the physician-patient relationship and as a basis for shaping recommendations at the institutional level. Furthermore, the patients' increased self-determination and modern opportunities for the medical laity to inform themselves lead to a less asymmetrical distribution of information between physician and patient and therefore require new interaction models. Based on the analysis presented here, the authors recommend that, apart from the physician's necessary individual ethics, greater consideration should be given to approaches of institutional ethics and hence to incentive systems within medical ethics.

  4. Challenges in process marginality for advanced technology nodes and tackling its contributors

    NASA Astrophysics Data System (ADS)

    Narayana Samy, Aravind; Schiwon, Roberto; Seltmann, Rolf; Kahlenberg, Frank; Katakamsetty, Ushasree

    2013-10-01

    Process margin is getting critical in the present node shrinkage scenario due to the physical limits reached (Rayleigh's criterion) using ArF lithography tools. K1 is used to its best for better resolution and to enhance the process margin (28nm metal patterning k1=0.31). In this paper, we would like to give an overview of various contributors in the advanced technology nodes which limit the process margins and how the challenges have been tackled in a modern foundry model. Advanced OPC algorithms are used to make the design content at the mask optimum for patterning. However, as we work at the physical limit, critical features (Hot-spots) are very susceptible to litho process variations. Furthermore, etch can have a significant impact as well. Pattern that still looks healthy at litho can fail due to etch interactions. This makes the traditional 2D contour output from ORC tools not able to predict accurately all defects and hence not able to fully correct it in the early mask tapeout phase. The above makes a huge difference in the fast ramp-up and high yield in a competitive foundry market. We will explain in this paper how the early introduction of 3D resist model based simulation of resist profiles (resist top-loss, bottom bridging, top-rounding, etc.,) helped in our prediction and correction of hot-spots in the early 28nm process development phase. The paper also discusses about the other overall process window reduction contributors due to mask 3D effects, wafer topography (focus shifts/variations) and how this has been addressed with different simulation efforts in a fast and timely manner.

  5. [Concern for children in family management texts].

    PubMed

    Kottek, Samuel S

    2002-06-01

    Hausväterliteratur designates works aimed at landlords and their wives in order to help them in the management of their estate. Among a wide-ranged list of topics tackled in these sizeable volumes, child welfare seldom fails to appear, though generally rather briefly. We consider in this paper a number of German works, most of them dating from the 17th century, though beginning with Johann Coler (1593) and winding up with Johann Joachim Becher (1714). These works include some advice on how to diagnose and manage the most common ailments, as well as some basic educational principles. A brief "pediatric" pharmacopoeia is often added. Although this review concerns only works in German, we have added references to a document taken from English literature, the diary of the clergyman and landlord Ralph Josselin. Dating from the same period (1643-1683), this document shows us how a landlord and his wife actually treated their sick children, thus shifting from theory to practice. "Hausväterliteratur" can be considered as an early stage of what was later termed "Domestic Medicine".

  6. The application of Signalling Theory to health-related trust problems: The example of herbal clinics in Ghana and Tanzania.

    PubMed

    Hampshire, Kate; Hamill, Heather; Mariwah, Simon; Mwanga, Joseph; Amoako-Sakyi, Daniel

    2017-09-01

    In contexts where healthcare regulation is weak and levels of uncertainty high, how do patients decide whom and what to trust? In this paper, we explore the potential for using Signalling Theory (ST, a form of Behavioural Game Theory) to investigate health-related trust problems under conditions of uncertainty, using the empirical example of 'herbal clinics' in Ghana and Tanzania. Qualitative, ethnographic fieldwork was conducted over an eight-month period (2015-2016) in eight herbal clinics in Ghana and ten in Tanzania, including semi-structured interviews with herbalists (N = 18) and patients (N = 68), plus detailed ethnographic observations and twenty additional key informant interviews. The data were used to explore four ST-derived predictions, relating to herbalists' strategic communication ('signalling') of their trustworthiness to patients, and patients' interpretation of those signals. Signalling Theory is shown to provide a useful analytical framework, allowing us to go beyond the primary trust problem addressed by other researchers - cataloguing observable indicators of trustworthiness - and providing tools for tackling the trickier secondary trust problem, where the trustworthiness of those indicators must be ascertained. Signalling Theory also enables a basis for comparative work between different empirical contexts that share the underlying condition of uncertainty. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  7. Primary care support for tackling obesity: a qualitative study of the perceptions of obese patients.

    PubMed

    Brown, Ian; Thompson, Joanne; Tod, Angela; Jones, Georgina

    2006-09-01

    Obesity has become a major public health issue and there is concern about the response of health services to patients who are obese. The perceptions of obese patients using primary care services have not been studied in depth. To explore obese patients' experiences and perceptions of support in primary care. Qualitative study with semi-structured interviews conducted in participants' homes. Five general practices contrasting in socioeconomic populations in Sheffield. Purposive sampling and semi-structured interviewing of 28 patients with a diverse range of ages, backgrounds, levels of obesity and experiences of primary care services. Participants typically felt reluctance when presenting with concerns about weight and ambivalence about the services received. They also perceived there to be ambivalence and a lack of resources on the part of the health services. Participants showed a strong sense of personal responsibility about their condition and stigma-related cognitions were common. These contributed to their ambivalence about using services and their sensitivity to its features. Good relationships with primary care professionals and more intensive support partly ameliorated these effects. The challenges of improving access to and quality of primary care support in tackling obesity are made more complex by patients' ambivalence and other effects of the stigma associated with obesity.

  8. Recovery strategies for tackling the impact of phenolic compounds in a UASB reactor treating coal gasification wastewater.

    PubMed

    Wang, Wei; Han, Hongjun

    2012-01-01

    The impact of phenolic compounds (around 3.2 g/L) resulted in a completely failed performance in a mesophilic UASB reactor treating coal gasification wastewater. The recovery strategies, including extension of HRT, dilution, oxygen-limited aeration, and addition of powdered activated carbon were evaluated in batch tests, in order to obtain the most appropriate way for the quick recovery of the failed reactor performance. Results indicated that addition of powdered activated carbon and oxygen-limited aeration were the best recovery strategies in the batch tests. In the UASB reactor, addition of powdered activated carbon of 1 g/L shortened the recovery time from 25 to 9 days and oxygen-limited aeration of 0-0.5 mgO2/L reduced the recovery time to 17 days. Reduction of bioavailable concentration of phenolic compounds and recovery of sludge activity were the decisive factors for the recovery strategies to tackle the impact of phenolic compounds in anaerobic treatment of coal gasification wastewater. Copyright © 2011 Elsevier Ltd. All rights reserved.

  9. Arithmetic and algebraic problem solving and resource allocation: the distinct impact of fluid and numerical intelligence.

    PubMed

    Dix, Annika; van der Meer, Elke

    2015-04-01

    This study investigates cognitive resource allocation dependent on fluid and numerical intelligence in arithmetic/algebraic tasks varying in difficulty. Sixty-six 11th grade students participated in a mathematical verification paradigm, while pupil dilation as a measure of resource allocation was collected. Students with high fluid intelligence solved the tasks faster and more accurately than those with average fluid intelligence, as did students with high compared to average numerical intelligence. However, fluid intelligence sped up response times only in students with average but not high numerical intelligence. Further, high fluid but not numerical intelligence led to greater task-related pupil dilation. We assume that fluid intelligence serves as a domain-general resource that helps to tackle problems for which domain-specific knowledge (numerical intelligence) is missing. The allocation of this resource can be measured by pupil dilation. Copyright © 2014 Society for Psychophysiological Research.

  10. Tackling Health Inequities and Reducing Obesity Prevalence: The EPODE Community-Based Approach.

    PubMed

    Borys, Jean-Michel; Richard, Pierre; Ruault du Plessis, Hugues; Harper, Pauline; Levy, Emile

    2016-01-01

    Tackling inequalities in overweight, obesity and related complications has become a top priority for European research and policy agendas. It is well-known that the health message often does not reach disadvantaged populations, a phenomenon that widens health inequalities. Ensemble Prévenons l'Obésité des Enfants (EPODE) methodology is an innovative approach to counteract obesity and improve health equity. EPODE for the Promotion of Health Equity (EPHE) has assessed the impact and sustainability of the EPODE methodology to diminish inequalities in childhood obesity prevention. The current data represent the results of the intermediate measurements that were obtained following EPHE interventions in 7 European communities across different countries. A total of 1,062 children aged 6-8 years and their parents from different socioeconomic backgrounds were observed for 2 years. A self-administrated questionnaire was sent to parents to measure the children's energy balance-related behaviors and their determinants. The Wilcoxon signed-rank test was used to test differences between baseline and intermediate measurements for each socioeconomic group. We observed changes in behaviors (fruit and vegetable consumption, sugary sweetened beverage consumption, screen exposure) and their related determinants, within the low and high education groups, which were associated with identified inequity gaps at baseline. Although statistical significance was not reached in most of the cases, greater improvements in behaviors were evident within the low education groups. Our findings show that, after EPODE interventions, the low socioeconomic groups improved their behavior compared to the other socio-economic groups. This indicates that the EPODE methodology has the capacity not only to reduce obesity prevalence but also to decrease health inequities. © 2016 The Author(s) Published by S. Karger AG, Basel.

  11. Tackling some of the most intricate geophysical challenges via high-performance computing

    NASA Astrophysics Data System (ADS)

    Khosronejad, A.

    2016-12-01

    Recently, world has been witnessing significant enhancements in computing power of supercomputers. Computer clusters in conjunction with the advanced mathematical algorithms has set the stage for developing and applying powerful numerical tools to tackle some of the most intricate geophysical challenges that today`s engineers face. One such challenge is to understand how turbulent flows, in real-world settings, interact with (a) rigid and/or mobile complex bed bathymetry of waterways and sea-beds in the coastal areas; (b) objects with complex geometry that are fully or partially immersed; and (c) free-surface of waterways and water surface waves in the coastal area. This understanding is especially important because the turbulent flows in real-world environments are often bounded by geometrically complex boundaries, which dynamically deform and give rise to multi-scale and multi-physics transport phenomena, and characterized by multi-lateral interactions among various phases (e.g. air/water/sediment phases). Herein, I present some of the multi-scale and multi-physics geophysical fluid mechanics processes that I have attempted to study using an in-house high-performance computational model, the so-called VFS-Geophysics. More specifically, I will present the simulation results of turbulence/sediment/solute/turbine interactions in real-world settings. Parts of the simulations I present are performed to gain scientific insights into the processes such as sand wave formation (A. Khosronejad, and F. Sotiropoulos, (2014), Numerical simulation of sand waves in a turbulent open channel flow, Journal of Fluid Mechanics, 753:150-216), while others are carried out to predict the effects of climate change and large flood events on societal infrastructures ( A. Khosronejad, et al., (2016), Large eddy simulation of turbulence and solute transport in a forested headwater stream, Journal of Geophysical Research:, doi: 10.1002/2014JF003423).

  12. Transfer Learning for Class Imbalance Problems with Inadequate Data.

    PubMed

    Al-Stouhi, Samir; Reddy, Chandan K

    2016-07-01

    A fundamental problem in data mining is to effectively build robust classifiers in the presence of skewed data distributions. Class imbalance classifiers are trained specifically for skewed distribution datasets. Existing methods assume an ample supply of training examples as a fundamental prerequisite for constructing an effective classifier. However, when sufficient data is not readily available, the development of a representative classification algorithm becomes even more difficult due to the unequal distribution between classes. We provide a unified framework that will potentially take advantage of auxiliary data using a transfer learning mechanism and simultaneously build a robust classifier to tackle this imbalance issue in the presence of few training samples in a particular target domain of interest. Transfer learning methods use auxiliary data to augment learning when training examples are not sufficient and in this paper we will develop a method that is optimized to simultaneously augment the training data and induce balance into skewed datasets. We propose a novel boosting based instance-transfer classifier with a label-dependent update mechanism that simultaneously compensates for class imbalance and incorporates samples from an auxiliary domain to improve classification. We provide theoretical and empirical validation of our method and apply to healthcare and text classification applications.

  13. Knowledge assessment of sports-related concussion among parents of children aged 5 years to 15 years enrolled in recreational tackle football.

    PubMed

    Mannings, Carol; Kalynych, Colleen; Joseph, Madeline Matar; Smotherman, Carmen; Kraemer, Dale F

    2014-09-01

    Sports-related concussion among professional, collegiate, and, more recently, high school athletes has received much attention from the media and medical community. To our knowledge, there is a paucity of research regarding parental knowledge of sports-related concussion. The aim of this study was to evaluate parental knowledge of concussion in young children who participated in recreational tackle football. Parents of children aged 5 years to 15 years attending recreational tackle football games were asked to complete an anonymous questionnaire based on the Centers for Disease Control and Prevention's Heads Up: Concussion in Youth Sports Quiz. The parents were asked about their level of agreement regarding statements that represent definition, symptoms, and treatment of concussion. A total of 310 of 369 parents (84% response rate) voluntarily completed the questionnaire, with 94% believing that their child had never had a concussion. However, only 13% (n = 41) could correctly identify all seven statements. Most did not identify that a concussion is considered a mild traumatic brain injury and can be achieved from something other than a direct blow to the head. Race, sex, and zip code had no significant association with correctly answering statements. Education (r = 0.24, p < 0.0001) and number of years the child played (r = 0.11, p = 0.049) had a small association. Fifty-three percent and 58% of the parents reported that someone had discussed the definition and the symptoms of concussion with them, respectively, with only about half reporting that information came from their health care provider. No parent was able to classify all symptoms listed as correctly related or not related to concussion. However, identification of correct concussion statements correlated with identification of correct symptoms (r = 0.25, p < 0.001). While most parents of young athletes demonstrated some knowledge regarding concussion, important misconceptions remain regarding the

  14. Physical inactivity as a policy problem: applying a concept from policy analysis to a public health issue.

    PubMed

    Rütten, Alfred; Abu-Omar, Karim; Gelius, Peter; Schow, Diana

    2013-03-07

    Despite the recent rapid development of policies to counteract physical inactivity (PI), only a small number of systematic analyses on the evolution of these policies exists. In this article we analyze how PI, as a public health issue, "translates" into a policy-making issue. First, we discuss why PI has become an increasingly important public health issue during the last two decades. We then follow Guy Peters and conceptualize PI as a "policy problem" that has the potential to be linked to policy instruments and policy impact. Analysis indicates that PI is a policy problem that i) is chronic in nature; ii) involves a high degree of political complexity; iii) can be disaggregated into smaller scales; iv) is addressed through interventions that can be difficult to "sell" to the public when their benefits are not highly divisible; v) cannot be solved by government spending alone; vi) must be addressed through a broad scope of activities; and vii) involves interdependencies among both multiple sectors and levels of government.We conclude that the new perspective on PI proposed in this article might be useful and important for i) describing and mapping policies to counteract PI in different contexts; ii) evaluating whether or not existing policy instruments are appropriate to the policy problem of PI, and iii) explaining the factors and processes that underlie policy development and implementation. More research is warranted in all these areas. In particular, we propose to focus on comparative analyses of how the problem of PI is defined and tackled in different contexts, and on the identification of truly effective policy instruments that are designed to "solve" the PI policy problem.

  15. A non-traditional fluid problem: transition between theoretical models from Stokes’ to turbulent flow

    NASA Astrophysics Data System (ADS)

    Salomone, Horacio D.; Olivieri, Néstor A.; Véliz, Maximiliano E.; Raviola, Lisandro A.

    2018-05-01

    In the context of fluid mechanics courses, it is customary to consider the problem of a sphere falling under the action of gravity inside a viscous fluid. Under suitable assumptions, this phenomenon can be modelled using Stokes’ law and is routinely reproduced in teaching laboratories to determine terminal velocities and fluid viscosities. In many cases, however, the measured physical quantities show important deviations with respect to the predictions deduced from the simple Stokes’ model, and the causes of these apparent ‘anomalies’ (for example, whether the flow is laminar or turbulent) are seldom discussed in the classroom. On the other hand, there are various variable-mass problems that students tackle during elementary mechanics courses and which are discussed in many textbooks. In this work, we combine both kinds of problems and analyse—both theoretically and experimentally—the evolution of a system composed of a sphere pulled by a chain of variable length inside a tube filled with water. We investigate the effects of different forces acting on the system such as weight, buoyancy, viscous friction and drag force. By means of a sequence of mathematical models of increasing complexity, we obtain a progressive fit that accounts for the experimental data. The contrast between the various models exposes the strengths and weaknessess of each one. The proposed experience can be useful for integrating concepts of elementary mechanics and fluids, and is suitable as laboratory practice, stressing the importance of the experimental validation of theoretical models and showing the model-building processes in a didactic framework.

  16. An LMI approach for the Integral Sliding Mode and H∞ State Feedback Control Problem

    NASA Astrophysics Data System (ADS)

    Bezzaoucha, Souad; Henry, David

    2015-11-01

    This paper deals with the state feedback control problem for linear uncertain systems subject to both matched and unmatched perturbations. The proposed control law is based on an the Integral Sliding Mode Control (ISMC) approach to tackle matched perturbations as well as the H∞ paradigm for robustness against unmatched perturbations. The proposed method also parallels the work presented in [1] which addressed the same problem and proposed a solution involving an Algebraic Riccati Equation (ARE)-based formulation. The contribution of this paper is concerned by the establishment of a Linear Matrix Inequality (LMI)-based solution which offers the possibility to consider other types of constraints such as 𝓓-stability constraints (pole assignment-like constraints). The proposed methodology is applied to a pilot three-tank system and experiment results illustrate the feasibility. Note that only a few real experiments have been rarely considered using SMC in the past. This is due to the high energetic behaviour of the control signal. It is important to outline that the paper does not aim at proposing a LMI formulation of an ARE. This is done since 1971 [2] and further discussed in [3] where the link between AREs and ARIs (algebraic Riccati inequality) is established for the H∞ control problem. The main contribution of this paper is to establish the adequate LMI-based methodology (changes of matrix variables) so that the ARE that corresponds to the particular structure of the mixed ISMC/H∞ structure proposed by [1] can be re-formulated within the LMI paradigm.

  17. Strange Deja Vu: Tackling Information Sharing Problems for Efforts Against Transnational Organized Crime

    DTIC Science & Technology

    2015-06-01

    as the demand in the US for drugs produced in Latin America (e.g., cocaine, marijuana , methamphetamines) remains, Latin American drug cartels will...6,100 kilograms of cocaine, 10,284 pounds of methamphetamine, 1,619 pounds of heroin, 349,304 pounds of marijuana , and nearly $150 million in United...benefits from increased information sharing with the Intelligence Community and other federal agencies through a favorable relationship with BIFS

  18. Mapping the use of research to support strategies tackling maternal and child health inequities: evidence from six countries in Africa and Latin America.

    PubMed

    Vargas, Emily; Becerril-Montekio, Victor; Gonzalez-Block, Miguel Ángel; Akweongo, Patricia; Hazel, Cynthia N A; Cuembelo, Maria de Fatima; Limbani, Felix; Bernardo, Wanderley; Muñoz, Fernando

    2016-01-07

    Striving to foster collaboration among countries suffering from maternal and child health (MCH) inequities, the MASCOT project mapped and analyzed the use of research in strategies tackling them in 11 low- and middle-income countries. This article aims to present the way in which research influenced MCH policies and programs in six of these countries - three in Africa and three in Latin America. Qualitative research using a thematic synthesis narrative process was used to identify and describe who is producing what kind of research, how research is funded, how inequities are approached by research and policies, the countries' research capacities, and the type of evidence base that MCH policies and programs use. Four tools were designed for these purposes: an online survey for researchers, a semi-structured interview with decision makers, and two content analysis guides: one for policy and programs documents and one for scientific articles. Three modalities of research utilization were observed in the strategies tackling MCH inequities in the six included countries - instrumental, conceptual and symbolic. Instrumental utilization directly relates the formulation and contents of the strategies with research results, and is the least used within the analyzed policies and programs. Even though research is considered as an important input to support decision making and most of the analyzed countries count five or six relevant MCH research initiatives, in most cases, the actual impact of research is not clearly identifiable. While MCH research is increasing in low- and middle-income countries, the impact of its outcomes on policy formulation is low. We did not identify a direct relationship between the nature of the financial support organizations and the kind of evidence utilization within the policy process. There is still a visible gap between researchers and policymakers regarding their different intentions to link evidence and decision making processes.

  19. The nanostructure problem

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Billinge, S.

    2010-03-22

    Diffraction techniques are making progress in tackling the difficult problem of solving the structures of nanoparticles and nanoscale materials. The great gift of x-ray crystallography has made us almost complacent in our ability to locate the three-dimensional coordinates of atoms in a crystal with a precision of around 10{sup -4} nm. However, the powerful methods of crystallography break down for structures in which order only extends over a few nanometers. In fact, as we near the one hundred year mark since the birth of crystallography, we face a resilient frontier in condensed matter physics: our inability to routinely and robustlymore » determine the structure of complex nanostructured and amorphous materials. Knowing the structure and arrangement of atoms in a solid is so fundamental to understanding its properties that the topic routinely occupies the early chapters of every solid-state physics textbook. Yet what has become clear with the emergence of nanotechnology is that diffraction data alone may not be enough to uniquely solve the structure of nanomaterials. As part of a growing effort to incorporate the results of other techniques to constrain x-ray refinements - a method called 'complex modeling' which is a simple but elegant approach for combining information from spectroscopy with diffraction data to solve the structure of several amorphous and nanostructured materials. Crystallography just works, so we rarely question how and why this is so, yet understanding the physics of diffraction can be very helpful as we consider the nanostructure problem. The relationship between the electron density distribution in three dimensions (i.e., the crystal structure) and an x-ray diffraction pattern is well established: the measured intensity distribution in reciprocal space is the square of the Fourier transform of the autocorrelation function <{rho}(r){rho}(r+r')> of the electron density distribution {rho}(r). The fact that we get the autocorrelation

  20. Computing the full spectrum of large sparse palindromic quadratic eigenvalue problems arising from surface Green's function calculations

    NASA Astrophysics Data System (ADS)

    Huang, Tsung-Ming; Lin, Wen-Wei; Tian, Heng; Chen, Guan-Hua

    2018-03-01

    Full spectrum of a large sparse ⊤-palindromic quadratic eigenvalue problem (⊤-PQEP) is considered arguably for the first time in this article. Such a problem is posed by calculation of surface Green's functions (SGFs) of mesoscopic transistors with a tremendous non-periodic cross-section. For this problem, general purpose eigensolvers are not efficient, nor is advisable to resort to the decimation method etc. to obtain the Wiener-Hopf factorization. After reviewing some rigorous understanding of SGF calculation from the perspective of ⊤-PQEP and nonlinear matrix equation, we present our new approach to this problem. In a nutshell, the unit disk where the spectrum of interest lies is broken down adaptively into pieces small enough that they each can be locally tackled by the generalized ⊤-skew-Hamiltonian implicitly restarted shift-and-invert Arnoldi (G⊤SHIRA) algorithm with suitable shifts and other parameters, and the eigenvalues missed by this divide-and-conquer strategy can be recovered thanks to the accurate estimation provided by our newly developed scheme. Notably the novel non-equivalence deflation is proposed to avoid as much as possible duplication of nearby known eigenvalues when a new shift of G⊤SHIRA is determined. We demonstrate our new approach by calculating the SGF of a realistic nanowire whose unit cell is described by a matrix of size 4000 × 4000 at the density functional tight binding level, corresponding to a 8 × 8nm2 cross-section. We believe that quantum transport simulation of realistic nano-devices in the mesoscopic regime will greatly benefit from this work.

  1. Chagas disease as a cause of heart failure and ventricular arrhythmias in patients long removed from endemic areas: an emerging problem in Europe.

    PubMed

    Vannucchi, Vieri; Tomberli, Benedetta; Zammarchi, Lorenzo; Fornaro, Alessandra; Castelli, Gabriele; Pieralli, Filippo; Berni, Andrea; Yacoub, Sophie; Bartoloni, Alessandro; Olivotto, Iacopo

    2015-12-01

    Chagas disease is a parasitic disease caused by the protozoan Trypanosoma cruzi. In endemic areas (South and Central America), Chagas disease represents a relevant public health issue, and is the most frequent cause of cardiomyopathy. In nonendemic areas, such as Europe, Chagas disease represents an emerging problem following the establishment of sizeable communities from Brazil and Bolivia. Chagas cardiomyopathy represents the most frequent and serious complication of chronic Chagas disease, affecting about 20-30% of patients, potentially leading to heart failure, arrhythmias, thromboembolism, stroke and sudden death. Because late complications of Chagas disease may develop several years or even decades after the acute infection, it may be extremely challenging to reach the correct diagnosis in patients long removed from the countries of origin. We report two examples of Chagas cardiomyopathy in South American women permanently residing in Italy for more than 20 years, presenting with cardiac manifestations ranging from left ventricular dysfunction and heart failure to isolated ventricular arrhythmias. The present review emphasizes that Chagas disease should be considered as a potential diagnosis in patients from endemic areas presenting with 'idiopathic' cardiac manifestations, even when long removed from their country of origin, with potential implications for treatment and control of Chagas disease transmission.

  2. Sequential Insertion Heuristic with Adaptive Bee Colony Optimisation Algorithm for Vehicle Routing Problem with Time Windows

    PubMed Central

    Jawarneh, Sana; Abdullah, Salwani

    2015-01-01

    This paper presents a bee colony optimisation (BCO) algorithm to tackle the vehicle routing problem with time window (VRPTW). The VRPTW involves recovering an ideal set of routes for a fleet of vehicles serving a defined number of customers. The BCO algorithm is a population-based algorithm that mimics the social communication patterns of honeybees in solving problems. The performance of the BCO algorithm is dependent on its parameters, so the online (self-adaptive) parameter tuning strategy is used to improve its effectiveness and robustness. Compared with the basic BCO, the adaptive BCO performs better. Diversification is crucial to the performance of the population-based algorithm, but the initial population in the BCO algorithm is generated using a greedy heuristic, which has insufficient diversification. Therefore the ways in which the sequential insertion heuristic (SIH) for the initial population drives the population toward improved solutions are examined. Experimental comparisons indicate that the proposed adaptive BCO-SIH algorithm works well across all instances and is able to obtain 11 best results in comparison with the best-known results in the literature when tested on Solomon’s 56 VRPTW 100 customer instances. Also, a statistical test shows that there is a significant difference between the results. PMID:26132158

  3. Fund the Child: Tackling Inequity & Antiquity in School Finance

    ERIC Educational Resources Information Center

    Thomas B. Fordham Foundation & Institute, 2006

    2006-01-01

    Education funding today is a mess, and a solution is needed that addresses its biggest problems: most disadvantaged students do not receive the funding they need; red tape and overhead waste time and money; and new types of education options, like charter schools, are starved for dollars. Unfortunately, until now, so-called solutions have…

  4. Teaching about Racial Equity in Introductory Physics Courses

    ERIC Educational Resources Information Center

    Daane, Abigail R.; Decker, Sierra R.; Sawtelle, Vashti

    2017-01-01

    Even after you have decided to tackle a problem like racial equity, it may seem daunting to broach the subject in a physics classroom. After all, the idea of a (typically White) instructor in power tackling a sensitive topic such as social justice can be scary in any (mostly White) classroom. Not only that, but physics is typically viewed as a…

  5. STEM the Boredom: Engage Students in the Australian Curriculum Using ICT with Problem-Based Learning and Assessment

    NASA Astrophysics Data System (ADS)

    Newhouse, Christopher Paul

    2017-02-01

    The well-being of modern economies and societies is increasingly requiring citizens to possess capabilities in integrating knowledge and skills in science, technology, engineering and science to solve problems. However, by the end of schooling, the majority of Australian students show little interest in these discipline areas and have no plans to continue study or work in them; many refer to these disciplines as boring. Further, they typically have little experience in integrating knowledge and skills from these disciplines and/or in applying this to solve relevant problems. Therefore, there is a need to engage students with such learning experiences to develop their interest and capabilities, particularly during the early years of secondary schooling. This is not easy for teachers to respond to, but with the support of modern digital technologies and the new Australian curriculum, the potential is expanded and the challenge is more readily achievable. However, appropriate pedagogies need to be supported that include more authentic approaches to assessment. Learning activities need to support students to integrate knowledge and skills across discipline areas in tackling real problems, and this also needs to be reflected in how students are assessed. In this paper, I will draw on personal experience as a teacher, a review of recent literature, components of the Australian Curriculum, and findings from research projects associated with my University research centre, to argue for, and illustrate how, teachers can orchestrate powerful learning activities to promote an interdisciplinary approach to STEM.

  6. Efficient algorithms for accurate hierarchical clustering of huge datasets: tackling the entire protein space.

    PubMed

    Loewenstein, Yaniv; Portugaly, Elon; Fromer, Menachem; Linial, Michal

    2008-07-01

    UPGMA (average linking) is probably the most popular algorithm for hierarchical data clustering, especially in computational biology. However, UPGMA requires the entire dissimilarity matrix in memory. Due to this prohibitive requirement, UPGMA is not scalable to very large datasets. We present a novel class of memory-constrained UPGMA (MC-UPGMA) algorithms. Given any practical memory size constraint, this framework guarantees the correct clustering solution without explicitly requiring all dissimilarities in memory. The algorithms are general and are applicable to any dataset. We present a data-dependent characterization of hardness and clustering efficiency. The presented concepts are applicable to any agglomerative clustering formulation. We apply our algorithm to the entire collection of protein sequences, to automatically build a comprehensive evolutionary-driven hierarchy of proteins from sequence alone. The newly created tree captures protein families better than state-of-the-art large-scale methods such as CluSTr, ProtoNet4 or single-linkage clustering. We demonstrate that leveraging the entire mass embodied in all sequence similarities allows to significantly improve on current protein family clusterings which are unable to directly tackle the sheer mass of this data. Furthermore, we argue that non-metric constraints are an inherent complexity of the sequence space and should not be overlooked. The robustness of UPGMA allows significant improvement, especially for multidomain proteins, and for large or divergent families. A comprehensive tree built from all UniProt sequence similarities, together with navigation and classification tools will be made available as part of the ProtoNet service. A C++ implementation of the algorithm is available on request.

  7. Tackling malnutrition among older people in the community.

    PubMed

    Denny, Anna

    2007-03-01

    Undernutrition - of both macronutrients and micronutrients - is still a surprisingly common problem among older people in the UK. There is a variety of nutritional supplements that community nurses need to be aware of in managing their patients' nutritional requirements. Different supplements are taken for different disease states. This article looks at the various nutrient and energy requirements that relate directly to clients on the district nurse's caseload. Some of the negative consequences of malnutrition of the older adult are discussed, as are the NICE guidelines for nutrition. Factors affecting dietary intake in older people are considered.

  8. Tackling saponin diversity in marine animals by mass spectrometry: data acquisition and integration.

    PubMed

    Decroo, Corentin; Colson, Emmanuel; Demeyer, Marie; Lemaur, Vincent; Caulier, Guillaume; Eeckhaut, Igor; Cornil, Jérôme; Flammang, Patrick; Gerbaux, Pascal

    2017-05-01

    Saponin analysis by mass spectrometry methods is nowadays progressively supplementing other analytical methods such as nuclear magnetic resonance (NMR). Indeed, saponin extracts from plant or marine animals are often constituted by a complex mixture of (slightly) different saponin molecules that requires extensive purification and separation steps to meet the requirement for NMR spectroscopy measurements. Based on its intrinsic features, mass spectrometry represents an inescapable tool to access the structures of saponins within extracts by using LC-MS, MALDI-MS, and tandem mass spectrometry experiments. The combination of different MS methods nowadays allows for a nice description of saponin structures, without extensive purification. However, the structural characterization process is based on low kinetic energy CID which cannot afford a total structure elucidation as far as stereochemistry is concerned. Moreover, the structural difference between saponins in a same extract is often so small that coelution upon LC-MS analysis is unavoidable, rendering the isomeric distinction and characterization by CID challenging or impossible. In the present paper, we introduce ion mobility in combination with liquid chromatography to better tackle the structural complexity of saponin congeners. When analyzing saponin extracts with MS-based methods, handling the data remains problematic for the comprehensive report of the results, but also for their efficient comparison. We here introduce an original schematic representation using sector diagrams that are constructed from mass spectrometry data. We strongly believe that the proposed data integration could be useful for data interpretation since it allows for a direct and fast comparison, both in terms of composition and relative proportion of the saponin contents in different extracts. Graphical Abstract A combination of state-of-the-art mass spectrometry methods, including ion mobility spectroscopy, is developed to afford a

  9. How will a life course framework be used to tackle wider social determinants of health?

    PubMed

    Nicolau, Belinda; Marcenes, Wagner

    2012-10-01

    The life course framework, proposed by Kuh and Schlomo in 1997, offers policy makers the means to understand the interaction between nature and nurture. This conceptual model illustrates how an individual's biological resources are influenced by their genetic endowment, their prenatal and postnatal development and their social and physical environment, both in early life and throughout the life course. Health is conceptualized as a dynamic process connecting biological and social elements that are affected by previous experiences and by present circumstances. Therefore, exposure at different stages of people's lives can either enhance or deplete the individual's health resources. Indeed, life course processes are of many kinds, including parent-child relationships, levels of social deprivation, the acquisition of emotional and behavioural assets in adolescence and the long-term effects of occupational hazards and work stress. The long-term effects of nature and nurture combine to influence disease outcomes. It is only in the last decade that theories, methods and new data have begun to be amalgamated, allowing us to further our understanding of health over the life course in ways that may eventually lead to more effective health policies and better health care. This article discusses life course concepts and how this framework can enlighten our understanding of wider social determinants of health, and provides a few examples of potential interventions to tackle their impact on health. © 2012 John Wiley & Sons A/S.

  10. [Problems and solutions in health care for chronic diseases. A qualitative study with patients and doctors].

    PubMed

    Ruiz Moral, Roger; Rodríguez Salvador, Juanjo; Pérula, Luis; Fernández, Isabel; Martínez, Jorge; Fernández, María Jesús; Yun, Antonio; Arboníes, Juan Carlos; Cabanás, María Auxiliadora; Luque, Luis; Mont, María Angeles

    2006-11-30

    Chronic diseases represent a challenge for health systems and the professionals most involved in chronic care. Despite biomedical advances, the results of care for chronic problems are not as good as they should be. To find out what doctors and patients think of care for some of the main chronic illnesses; to detect concrete areas of deficit and lack of satisfaction felt by both sides and possible lines of improvement; to raise mutual understanding between patients and doctors. Forty-one patients with fibromyalgia or diabetes mellitus, carers for people with Alzheimer's and breast cancer patients. Forty-three family doctors involved in health care delivery to this kind of patient. Four discussion groups. Transcription and syntactical, semantic and pragmatic contents analysis, with both pre-established and emerging categories of consensus. Patients thought, with different nuances as a function of the problem put forward, that questions of respectful, human and integrated care, clear and suitable information, and consistent follow-up were important and insufficiently covered by doctors and health services. Doctors thought that many of their efforts in caring for these patients were useless, and thought it important to reconsider their clinical responsibilities and the patient-doctor relationship. Doctors highlighted the limitations in the health care resources available for working with these patients. To tackle prevalent chronic problems requires, in the view of doctors and patients, important modifications that are related mainly to the kind of relationship between the two, with new clinical responsibilities and certain organisational care delivery features.

  11. Problems and Challenges of Educational Policies in Latin America. The Argentina Viewpoint

    ERIC Educational Resources Information Center

    Muscará, Francisco

    2013-01-01

    The objective of this article is to describe the most significant changes which are being carried out in Latin-American educational systems, taking Argentina as a point of reference. To that end, this comparative study tackles the following essential aspects: the principle of equal opportunities and social cohesion; decentralisation of educational…

  12. U.S.A.: Illiteracy--Why and How to Tackle It.

    ERIC Educational Resources Information Center

    Literacy Work, 1978

    1978-01-01

    Reviews the adult illiteracy problem in the United States and explains a U.S. experimental adult literacy program titled the apperception interaction method (AIM). It is noted that AIM involves reading, writing, discussion, and the taking of practical action by participants. (LRA)

  13. Tackling reliability and construct validity: the systematic development of a qualitative protocol for skill and incident analysis.

    PubMed

    Savage, Trevor Nicholas; McIntosh, Andrew Stuart

    2017-03-01

    It is important to understand factors contributing to and directly causing sports injuries to improve the effectiveness and safety of sports skills. The characteristics of injury events must be evaluated and described meaningfully and reliably. However, many complex skills cannot be effectively investigated quantitatively because of ethical, technological and validity considerations. Increasingly, qualitative methods are being used to investigate human movement for research purposes, but there are concerns about reliability and measurement bias of such methods. Using the tackle in Rugby union as an example, we outline a systematic approach for developing a skill analysis protocol with a focus on improving objectivity, validity and reliability. Characteristics for analysis were selected using qualitative analysis and biomechanical theoretical models and epidemiological and coaching literature. An expert panel comprising subject matter experts provided feedback and the inter-rater reliability of the protocol was assessed using ten trained raters. The inter-rater reliability results were reviewed by the expert panel and the protocol was revised and assessed in a second inter-rater reliability study. Mean agreement in the second study improved and was comparable (52-90% agreement and ICC between 0.6 and 0.9) with other studies that have reported inter-rater reliability of qualitative analysis of human movement.

  14. Efficient algorithms for accurate hierarchical clustering of huge datasets: tackling the entire protein space

    PubMed Central

    Loewenstein, Yaniv; Portugaly, Elon; Fromer, Menachem; Linial, Michal

    2008-01-01

    Motivation: UPGMA (average linking) is probably the most popular algorithm for hierarchical data clustering, especially in computational biology. However, UPGMA requires the entire dissimilarity matrix in memory. Due to this prohibitive requirement, UPGMA is not scalable to very large datasets. Application: We present a novel class of memory-constrained UPGMA (MC-UPGMA) algorithms. Given any practical memory size constraint, this framework guarantees the correct clustering solution without explicitly requiring all dissimilarities in memory. The algorithms are general and are applicable to any dataset. We present a data-dependent characterization of hardness and clustering efficiency. The presented concepts are applicable to any agglomerative clustering formulation. Results: We apply our algorithm to the entire collection of protein sequences, to automatically build a comprehensive evolutionary-driven hierarchy of proteins from sequence alone. The newly created tree captures protein families better than state-of-the-art large-scale methods such as CluSTr, ProtoNet4 or single-linkage clustering. We demonstrate that leveraging the entire mass embodied in all sequence similarities allows to significantly improve on current protein family clusterings which are unable to directly tackle the sheer mass of this data. Furthermore, we argue that non-metric constraints are an inherent complexity of the sequence space and should not be overlooked. The robustness of UPGMA allows significant improvement, especially for multidomain proteins, and for large or divergent families. Availability: A comprehensive tree built from all UniProt sequence similarities, together with navigation and classification tools will be made available as part of the ProtoNet service. A C++ implementation of the algorithm is available on request. Contact: lonshy@cs.huji.ac.il PMID:18586742

  15. Fast parallel molecular algorithms for DNA-based computation: solving the elliptic curve discrete logarithm problem over GF2.

    PubMed

    Li, Kenli; Zou, Shuting; Xv, Jin

    2008-01-01

    Elliptic curve cryptographic algorithms convert input data to unrecognizable encryption and the unrecognizable data back again into its original decrypted form. The security of this form of encryption hinges on the enormous difficulty that is required to solve the elliptic curve discrete logarithm problem (ECDLP), especially over GF(2(n)), n in Z+. This paper describes an effective method to find solutions to the ECDLP by means of a molecular computer. We propose that this research accomplishment would represent a breakthrough for applied biological computation and this paper demonstrates that in principle this is possible. Three DNA-based algorithms: a parallel adder, a parallel multiplier, and a parallel inverse over GF(2(n)) are described. The biological operation time of all of these algorithms is polynomial with respect to n. Considering this analysis, cryptography using a public key might be less secure. In this respect, a principal contribution of this paper is to provide enhanced evidence of the potential of molecular computing to tackle such ambitious computations.

  16. Tackling breast cancer chemoresistance with nano-formulated siRNA

    PubMed Central

    Jones, SK; Merkel, OM

    2017-01-01

    Breast cancer is the leading cancer diagnosed in women and the second leading cause of cancer-related deaths in women. Current limitations to standard chemotherapy in the clinic are extensively researched, including problems arising from repeated treatments with the same drugs. The phenomenon that cancer cells become resistant toward certain chemo drugs is called chemotherapy resistance. In this review, we are focusing on nanoformulation of siRNA for the fight against breast cancer chemoresistance. PMID:27648580

  17. Applications of the Galton Watson process to human DNA evolution and demography

    NASA Astrophysics Data System (ADS)

    Neves, Armando G. M.; Moreira, Carlos H. C.

    2006-08-01

    We show that the problem of existence of a mitochondrial Eve can be understood as an application of the Galton-Watson process and presents interesting analogies with critical phenomena in Statistical Mechanics. In the approximation of small survival probability, and assuming limited progeny, we are able to find for a genealogic tree the maximum and minimum survival probabilities over all probability distributions for the number of children per woman constrained to a given mean. As a consequence, we can relate existence of a mitochondrial Eve to quantitative demographic data of early mankind. In particular, we show that a mitochondrial Eve may exist even in an exponentially growing population, provided that the mean number of children per woman Nbar is constrained to a small range depending on the probability p that a child is a female. Assuming that the value p≈0.488 valid nowadays has remained fixed for thousands of generations, the range where a mitochondrial Eve occurs with sizeable probability is 2.0492problem of joint existence of a mitochondrial Eve and a Y chromosome Adam. We remark why this problem may not be treated by two independent Galton-Watson processes and present some simulation results suggesting that joint existence of Eve and Adam occurs with sizeable probability in the same Nbar range. Finally, we show that the Galton-Watson process may be a useful approximation in treating biparental population models, allowing us to reproduce some results previously obtained by Chang and Derrida et al.

  18. Bell's theorem, the measurement problem, Newton's self-gravitation and its connections to violations of the discrete symmetries C, P, T

    NASA Astrophysics Data System (ADS)

    Hiesmayr, Beatrix C.

    2015-07-01

    About 50 years ago John St. Bell published his famous Bell theorem that initiated a new field in physics. This contribution discusses how discrete symmetries relate to the big open questions of quantum mechanics, in particular: (i) how correlations stronger than those predicted by theories sharing randomness (Bell's theorem) relate to the violation of the CP symmetry and the P symmetry; and its relation to the security of quantum cryptography, (ii) how the measurement problem (“why do we observe no tables in superposition?”) can be polled in weakly decaying systems, (iii) how strongly and weakly interacting quantum systems are affected by Newton's self gravitation. These presented preliminary results show that the meson-antimeson systems and the hyperon- antihyperon systems are a unique laboratory to tackle deep fundamental questions and to contribute to the understand what impact the violation of discrete symmetries has.

  19. Evaluation of the "Eat Better Feel Better" Cooking Programme to Tackle Barriers to Healthy Eating.

    PubMed

    Garcia, Ada L; Reardon, Rebecca; Hammond, Elizabeth; Parrett, Alison; Gebbie-Diben, Anne

    2017-04-04

    We evaluated a 6-week community-based cooking programme, "Eat Better Feel Better", aimed at tackling barriers to cooking and healthy eating using a single-group repeated measures design. 117 participants enrolled, 62 completed baseline and post-intervention questionnaires, and 17 completed these and a 3-4 months follow-up questionnaire. Most participants were female, >45 years, and socioeconomically deprived. Confidence constructs changed positively from baseline to post-intervention (medians, scale 1 "not confident" to 7 "very confident"): "cooking using raw ingredients" (4, 6 p < 0.003), "following simple recipe" (5, 6 p = 0.003), "planning meals before shopping" (4, 5 p = <0.001), "shopping on a budget (4, 5 p = 0.044), "shopping healthier food" (4, 5 p = 0.007), "cooking new foods" (3, 5 p < 0.001), "cooking healthier foods" (4, 5 p = 0.001), "storing foods safely" (5, 6 p = 0.002); "using leftovers" (4, 5 p = 0.002), "cooking raw chicken" (5, 6 p = 0.021), and "reading food labels" (4, 5 p < 0.001). "Microwaving ready-meals" decreased 46% to 39% ( p = 0.132). "Preparing meals from scratch" increased 48% to 59% ( p = 0.071). Knowledge about correct portion sizes increased 47% to 74% ( p = 0.002). Spending on ready-meals/week decreased. Follow-up telephone interviewees ( n = 42) reported developing healthier eating patterns, spending less money/wasting less food, and preparing more meals/snacks from raw ingredients. The programme had positive effects on participants' cooking skills confidence, helped manage time, and reduced barriers of cost, waste, and knowledge.).

  20. Problems with sex among gay and bisexual men with diagnosed HIV in the United Kingdom.

    PubMed

    Bourne, Adam; Hickson, Ford; Keogh, Peter; Reid, David; Weatherburn, Peter

    2012-10-29

    A significant research literature exists that details the sexual health and sexual behaviour of gay and bisexual men who have diagnosed HIV. However, much of this research has focussed on HIV transmission risk behaviours among this group, rather than seeking to understand their sexual health and sexual well-being more broadly. There have been growing calls for interventions to support people with diagnosed HIV to achieve health and well-being, including sexual health and well-being. A detailed understanding of the problems people in this group face, and how they might be overcome, is required to facilitate such interventions. One thousand two hundred and seventeen gay and bisexual men with diagnosed HIV were recruited by convenience sampling through charitable AIDS service organisations, genitourinary medicine clinics and local authority agencies to complete a survey of their health and social care needs. Respondents were asked to report any problems they had with regards to sex during the 12 months prior to survey completion. They were also asked to describe what support might help them to overcome any problems they experienced. Overall, 70.5% of the gay and bisexual men with diagnosed HIV completing the survey reported one or more problems with sex within the previous 12 months. Most commonly reported problems include loss of libido (44.0%, n=540), poor self-image or low self confidence (43.9%, n=534), worries about passing HIV to potential sexual partners (37.3%, n=454), and fears of rejection from sexual partners (34.7%, n=422). Responses varied according to age, time since diagnosis, and whether or not the respondent was currently taking anti-retroviral therapy. Qualitative analysis of data relating to what support might help men overcome problems with sex indicate a need for therapeutic support to increase self esteem and confidence, clarity on criminalisation of HIV transmission, the tackling of HIV related stigma and help to achieve a higher quality (as

  1. Additional Insights Into Problem Definition and Positioning From Social Science Comment on "Four Challenges That Global Health Networks Face".

    PubMed

    Quissell, Kathryn

    2017-09-10

    Commenting on a recent editorial in this journal which presented four challenges global health networks will have to tackle to be effective, this essay discusses why this type of analysis is important for global health scholars and practitioners, and why it is worth understanding and critically engaging with the complexities behind these challenges. Focusing on the topics of problem definition and positioning, I outline additional insights from social science theory to demonstrate how networks and network researchers can evaluate these processes, and how these processes contribute to better organizing, advocacy, and public health outcomes. This essay also raises multiple questions regarding these processes for future research. © 2018 The Author(s); Published by Kerman University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

  2. Service-based Solutions.

    ERIC Educational Resources Information Center

    Cummings, Lynda; Winston, Michael

    1998-01-01

    Describes the Solutions model used at Shelley High School in Idaho which gives students the opportunity to gain practical experience while tackling community problems. This approach is built on the three fundamentals of an integrated curriculum, a problem-solving focus, and service-based learning. Sample problems include increasing certain trout…

  3. Synthesis and review: Tackling the nitrogen management challenge: from global to local scales

    NASA Astrophysics Data System (ADS)

    Reis, Stefan; Bekunda, Mateete; Howard, Clare M.; Karanja, Nancy; Winiwarter, Wilfried; Yan, Xiaoyuan; Bleeker, Albert; Sutton, Mark A.

    2016-12-01

    ) and the identification of policy and technology solutions to tackle global nitrogen management issues (IV), this will enable countries to fulfil their regional and global commitments.

  4. Sugar-sweetened beverages in Pacific Island countries and territories: problems and solutions?

    PubMed

    Snowdon, W

    2014-03-01

    Non-communicable diseases are a major problem in the Pacific Islands, with poor diets an important contributing factor. Available data suggests high levels of intake of sugar-sweetened beverages (SSBs) across the region, and particularly in adolescents. Due to concerns about the risks to health of high intakes, efforts have been made across the region to reduce the intake of SSBs. French Polynesia, Nauru, Cook Islands, Tonga and Fiji have implemented sales or excise taxes on SSBs to increase the price to the consumer. Many countries in the region have adopted school food policies which intend to limit or ban access to SSBs in schools. Guam also adopted legislation to ensure that healthier foods and beverages were available in all vending machines in schools. Efforts to control advertising and sponsorship of SSBs have been limited to-date in the region, although some school food policies do restrict advertising and sponsorship in schools, school grounds and school vehicles. Efforts around education and awareness raising have shown mixed success in terms of changing behaviour. Greater attention is needed to evaluate the impact of these measures to ensure that actions are effective, and to increase the evidence regionally of the most effective approaches to tackle SSBs.

  5. Responsibility without legal authority? Tackling alcohol-related health harms through licensing and planning policy in local government.

    PubMed

    Martineau, F P; Graff, H; Mitchell, C; Lock, K

    2014-09-01

    The power to influence many social determinants of health lies within local government sectors that are outside public health's traditional remit. We analyse the challenges of achieving health gains through local government alcohol control policies, where legal and professional practice frameworks appear to conflict with public health action. Current legislation governing local alcohol control in England and Wales is reviewed and analysed for barriers and opportunities to implement effective population-level health interventions. Case studies of local government alcohol control practices are described. Addressing alcohol-related health harms is constrained by the absence of a specific legal health licensing objective and differences between public health and legal assessments of the relevance of health evidence to a specific place. Local governments can, however, implement health-relevant policies by developing local evidence for alcohol-related health harms; addressing cumulative impact in licensing policy statements and through other non-legislative approaches such as health and non-health sector partnerships. Innovative local initiatives-for example, minimum unit pricing licensing conditions-can serve as test cases for wider national implementation. By combining the powers available to the many local government sectors involved in alcohol control, alcohol-related health and social harms can be tackled through existing local mechanisms. © The Author 2013. Published by Oxford University Press on behalf of Faculty of Public Health.

  6. Policy intervention for arsenic mitigation in drinking water in rural habitations in India: achievements and challenges.

    PubMed

    Shrivastava, Brajesh K

    2016-10-01

    This article provides updated status of the arsenic affected rural habitations in India, summarizes the policy initiatives of the Ministry of Drinking Water & Sanitation (Government of India), reviews the technologies for arsenic treatment and analyses the progress made by states in tackling arsenic problems in rural habitations. It also provides a list of constraints based on experiences and recommends suggested measures to tackle arsenic problems in an holistic manner. It is expected that the paper would be useful for policy formulators in states, non-government organizations, researchers of academic and scientific institutions and programme managers working in the area of arsenic mitigation in drinking water, especially in developing countries, as it provides better insights compared to other available information in India on mitigating arsenic problems in drinking water in rural areas.

  7. Mental health problems of undocumented migrants (UMs) in the Netherlands: a qualitative exploration of help-seeking behaviour and experiences with primary care

    PubMed Central

    Teunissen, Erik; Sherally, Jamilah; van den Muijsenbergh, Maria; Dowrick, Chris; van Weel-Baumgarten, Evelyn; van Weel, Chris

    2014-01-01

    Objective To explore health-seeking behaviour and experiences of undocumented migrants (UMs) in general practice in relation to mental health problems. Design Qualitative study using semistructured interviews and thematic analysis. Participants 15 UMs in the Netherlands, varying in age, gender, country of origin and education; inclusion until theoretical saturation was reached. Setting 4 cities in the Netherlands. Results UMs consider mental health problems to be directly related to their precarious living conditions. For support, they refer to friends and religion first, the general practitioner (GP) is their last resort. Barriers for seeking help include taboo on mental health problems, lack of knowledge of and trust in GPs competencies regarding mental health and general barriers in accessing healthcare as an UM (lack of knowledge of the right to access healthcare, fear of prosecution, financial constraints and practical difficulties). Once access has been gained, satisfaction with care is high. This is primarily due to the attitude of the GPs and the effectiveness of the treatment. Reasons for dissatisfaction with GP care are an experienced lack of time, lack of personal attention and absence of physical examination. Expectations of the GP vary, medication for mental health problems is not necessarily seen as a good practice. Conclusions UMs often see their precarious living conditions as an important determinant of their mental health; they do not easily seek help for mental health problems and various barriers hamper access to healthcare for them. Rather than for medication, UMs are looking for encouragement and support from their GP. We recommend that barriers experienced in seeking professional care are tackled at an institutional level as well as at the level of GP. PMID:25416057

  8. Clinical leadership: Part 2. Transforming leadership.

    PubMed

    Sheridan, Mary; Corney, Barbra

    2003-08-01

    The second article in a series of three focuses on group-driven approaches to tackling problems and shows how good leadership relies on teamwork and respect for colleagues, helping to enhance problem-solving and enabling you to build on your team's successes.

  9. Closing the Student Achievement Gap in California's Elementary Schools: A Lead Teachers' Perspective on Transformational Instructional Leadership

    ERIC Educational Resources Information Center

    Hays, Kelli

    2010-01-01

    This study has tackled the thorny problem of closing the Student Achievement Gap (SAG) in California's elementary schools. To address that problem, an "Integrated" form of educational leadership called Transformational Instructional Leadership (TIL), a form grounded in "best practices" of Transformational and Instructional…

  10. Managing Problems Before Problems Manage You.

    PubMed

    Grigsby, Jim

    2015-01-01

    Every day we face problems, both personal and professional, and our initial reaction determines how well we solve those problems. Whether a problem is minor or major, short-term or lingering, there are techniques we can employ to help manage the problem and the problem-solving process. This article, based on my book Don't Tick Off The Gators! Managing Problems Before Problems Manage You, presents 12 different concepts for managing problems, not "cookie cutter" solutions, but different ideas that you can apply as they fit your circumstances.

  11. Does Virtual Team Composition Matter? Trait and Problem-Solving Configuration Effects on Team Performance

    ERIC Educational Resources Information Center

    Turel, Ofir; Zhang, Yi

    2010-01-01

    Due to the increased importance and usage of self-managed virtual teams, many recent studies have examined factors that affect their success. One such factor that merits examination is the configuration or composition of virtual teams. This article tackles this point by (1) empirically testing trait-configuration effects on virtual team…

  12. Finite element solution of nonlinear eddy current problems with periodic excitation and its industrial applications.

    PubMed

    Bíró, Oszkár; Koczka, Gergely; Preis, Kurt

    2014-05-01

    An efficient finite element method to take account of the nonlinearity of the magnetic materials when analyzing three-dimensional eddy current problems is presented in this paper. The problem is formulated in terms of vector and scalar potentials approximated by edge and node based finite element basis functions. The application of Galerkin techniques leads to a large, nonlinear system of ordinary differential equations in the time domain. The excitations are assumed to be time-periodic and the steady-state periodic solution is of interest only. This is represented either in the frequency domain as a finite Fourier series or in the time domain as a set of discrete time values within one period for each finite element degree of freedom. The former approach is the (continuous) harmonic balance method and, in the latter one, discrete Fourier transformation will be shown to lead to a discrete harmonic balance method. Due to the nonlinearity, all harmonics, both continuous and discrete, are coupled to each other. The harmonics would be decoupled if the problem were linear, therefore, a special nonlinear iteration technique, the fixed-point method is used to linearize the equations by selecting a time-independent permeability distribution, the so-called fixed-point permeability in each nonlinear iteration step. This leads to uncoupled harmonics within these steps. As industrial applications, analyses of large power transformers are presented. The first example is the computation of the electromagnetic field of a single-phase transformer in the time domain with the results compared to those obtained by traditional time-stepping techniques. In the second application, an advanced model of the same transformer is analyzed in the frequency domain by the harmonic balance method with the effect of the presence of higher harmonics on the losses investigated. Finally a third example tackles the case of direct current (DC) bias in the coils of a single-phase transformer.

  13. Adult Learning and Development. Perspectives from Educational Psychology. The Educational Psychology Series.

    ERIC Educational Resources Information Center

    Smith, M. Cecil, Ed.; Pourchot, Thomas, Ed.

    Leading educational psychologists address problems in adult development and learning in this book. "What Does Educational Psychology Know about Adult Learning and Development?" (M. Cecil Smith, Thomas Pourchot) is the introduction. "We Learn, Therefore We Develop" (Nira Granott) tackles the problem of distinguishing between…

  14. Tackling inequalities in obesity: a protocol for a systematic review of the effectiveness of public health interventions at reducing socioeconomic inequalities in obesity among adults.

    PubMed

    Bambra, Clare L; Hillier, Frances C; Moore, Helen J; Cairns-Nagi, Joanne-Marie; Summerbell, Carolyn D

    2013-05-10

    Socioeconomic inequalities in obesity and associated risk factors for obesity are widening throughout developed countries worldwide. Tackling obesity is high on the public health agenda both in the United Kingdom and internationally. However, what works in terms of interventions that are able to reduce inequalities in obesity is lacking. The review will examine public health interventions at the individual, community and societal level that might reduce inequalities in obesity among adults aged 18 years and over, in any setting and in any country. The following electronic databases will be searched: MEDLINE, EMBASE, CINAHL, PsycINFO, Social Science Citation Index, ASSIA, IBSS, Sociological Abstracts, and the NHS Economic Evaluation Database. Database searches will be supplemented with website and gray literature searches. No studies will be excluded based on language, country or publication date. Randomized and non-randomized controlled trials, prospective and retrospective cohort studies (with/without control groups) and prospective repeat cross-sectional studies (with/without control groups) that have a primary outcome that is a proxy for body fatness and have examined differential effects with regard to socioeconomic status (education, income, occupation, social class, deprivation, poverty) or where the intervention has been targeted specifically at disadvantaged groups or deprived areas will be included. Study inclusion, data extraction and quality appraisal will be conducted by two reviewers. Meta-analysis and narrative synthesis will be conducted. The main analysis will examine the effects of 1) individual, 2) community and 3) societal level public health interventions on socioeconomic inequalities in adult obesity. Interventions will be characterized by their level of action and their approach to tackling inequalities. Contextual information on how such public health interventions are organized, implemented and delivered will also be examined. The review

  15. A quantum annealing approach for fault detection and diagnosis of graph-based systems

    NASA Astrophysics Data System (ADS)

    Perdomo-Ortiz, A.; Fluegemann, J.; Narasimhan, S.; Biswas, R.; Smelyanskiy, V. N.

    2015-02-01

    Diagnosing the minimal set of faults capable of explaining a set of given observations, e.g., from sensor readouts, is a hard combinatorial optimization problem usually tackled with artificial intelligence techniques. We present the mapping of this combinatorial problem to quadratic unconstrained binary optimization (QUBO), and the experimental results of instances embedded onto a quantum annealing device with 509 quantum bits. Besides being the first time a quantum approach has been proposed for problems in the advanced diagnostics community, to the best of our knowledge this work is also the first research utilizing the route Problem → QUBO → Direct embedding into quantum hardware, where we are able to implement and tackle problem instances with sizes that go beyond previously reported toy-model proof-of-principle quantum annealing implementations; this is a significant leap in the solution of problems via direct-embedding adiabatic quantum optimization. We discuss some of the programmability challenges in the current generation of the quantum device as well as a few possible ways to extend this work to more complex arbitrary network graphs.

  16. Social capital and health: measuring and understanding social capital at a local level could help to tackle health inequalities more effectively.

    PubMed

    Pilkington, Paul

    2002-09-01

    This paper examines whether an understanding of the concept of social capital and its local measurement can help to tackle inequalities in health within and across communities. The paper concludes that the concept of social capital offers a valuable opportunity to help public health professionals understand how to approach inequalities in health with a greater awareness of the social processes affecting the health of communities. The measurement of social capital has been problematic. However, new guidance from the Health Development Agency (HDA) provides a useful tool for developing social capital research. A greater understanding of whether, and how social capital relates to health will help to improve strategies to reduce health inequalities at the community level. Public health professionals contributing to community development strategies such as Neighbourhood Renewal Projects, Community Safety Partnerships, Health Action Zones and Health Improvement Programmes (HImPs) should encourage thought to be given about the role that an understanding of social capital could play in making these strategies more effective. Using the HDA measurement tool locally could be one way of doing this.

  17. Challenging stigma and discrimination in communities: a focus group study identifying UK mental health service users' main campaign priorities.

    PubMed

    Pinfold, Vanessa; Byrne, Peter; Toulmin, Hilary

    2005-06-01

    Stigma and discrimination experienced by people with mental health problems have been identified as major obstacles to treatment and recovery. Less is known about how to effectively tackle stigma-discrimination, although there are numerous international, national and local programmes attempting to improve public mental health literacy and anti-discrimination evidenced based practice. To explore mental health service users' views on how campaigns to address stigma and discrimination should prioritise their actions. Qualitative study using focus group discussions, involving 33 persons aged between 25 and 75. A triad of diminished credibility, dis-empowerment with particular reference to communication problems and avoidance by their social network defined experiences of stigma. Reactions to stigma can be placed in four categories: avoid stigma, resign yourself to it, challenge it, or distance yourself from others with a mental health problem. A range of solutions was discussed with most favouring changes within the health services that are currently supporting them over traditional educational programmes with the public. For mental health service users stigma must be tackled on many different levels reflecting the varied and complex impact that negative social reactions have on an individual's life. When asked to prioritise one area, most service users in our sample highlighted reforms within the health service for tackling stigma and discrimination.

  18. University Students' Strategies for Constructing Hypothesis When Tackling Paper-and-Pencil Tasks in Physics

    ERIC Educational Resources Information Center

    Guisasola, Jenaro; Ceberio, Mikel; Zubimendi, Jose Luis

    2006-01-01

    The study we present tries to explore how first year engineering students formulate hypotheses in order to construct their own problem solving structure when confronted with problems in physics. Under the constructivistic perspective of the teaching-learning process, the formulation of hypotheses plays a key role in contrasting the coherence of…

  19. Tackling missing radiographic progression data: multiple imputation technique compared with inverse probability weights and complete case analysis.

    PubMed

    Descalzo, Miguel Á; Garcia, Virginia Villaverde; González-Alvaro, Isidoro; Carbonell, Jordi; Balsa, Alejandro; Sanmartí, Raimon; Lisbona, Pilar; Hernandez-Barrera, Valentín; Jiménez-Garcia, Rodrigo; Carmona, Loreto

    2013-02-01

    To describe the results of different statistical ways of addressing radiographic outcome affected by missing data--multiple imputation technique, inverse probability weights and complete case analysis--using data from an observational study. A random sample of 96 RA patients was selected for a follow-up study in which radiographs of hands and feet were scored. Radiographic progression was tested by comparing the change in the total Sharp-van der Heijde radiographic score (TSS) and the joint erosion score (JES) from baseline to the end of the second year of follow-up. MI technique, inverse probability weights in weighted estimating equation (WEE) and CC analysis were used to fit a negative binomial regression. Major predictors of radiographic progression were JES and joint space narrowing (JSN) at baseline, together with baseline disease activity measured by DAS28 for TSS and MTX use for JES. Results from CC analysis show larger coefficients and s.e.s compared with MI and weighted techniques. The results from the WEE model were quite in line with those of MI. If it seems plausible that CC or MI analysis may be valid, then MI should be preferred because of its greater efficiency. CC analysis resulted in inefficient estimates or, translated into non-statistical terminology, could guide us into inaccurate results and unwise conclusions. The methods discussed here will contribute to the use of alternative approaches for tackling missing data in observational studies.

  20. The theory-practice gap in nurse education: its causes and possible solutions. Findings from an action research study.

    PubMed

    McCaugherty, D

    1991-09-01

    Kurt Lewin, the originator of action research, proposed that it was valuable not only for innovating change, but also the process of change could lead to new insights into the nature of the problem that was being tackled. This action research project developed and evaluated a teaching model that aimed to help RGN (registered general nurse) students to bridge the theory-practice gap. During the course of this work, the possible reasons for a theory-practice gap started to become clear. This paper provides a discussion of these factors. The viewpoint for this discussion is that of the student nurse. The student is assumed to 'own' the problem and it is from her perspective that the theory-practice gap is analysed. The paper includes a critical examination of books, lectures, the school curriculum and ward nursing practice. Finally, possible solutions to the theory-practice problem are discussed and it is hoped that these will provide a rational basis for tackling the problem.

  1. Tackling the conformational sampling of larger flexible compounds and macrocycles in pharmacology and drug discovery.

    PubMed

    Chen, I-Jen; Foloppe, Nicolas

    2013-12-15

    Computational conformational sampling underpins much of molecular modeling and design in pharmaceutical work. The sampling of smaller drug-like compounds has been an active area of research. However, few studies have tested in details the sampling of larger more flexible compounds, which are also relevant to drug discovery, including therapeutic peptides, macrocycles, and inhibitors of protein-protein interactions. Here, we investigate extensively mainstream conformational sampling methods on three carefully curated compound sets, namely the 'Drug-like', larger 'Flexible', and 'Macrocycle' compounds. These test molecules are chemically diverse with reliable X-ray protein-bound bioactive structures. The compared sampling methods include Stochastic Search and the recent LowModeMD from MOE, all the low-mode based approaches from MacroModel, and MD/LLMOD recently developed for macrocycles. In addition to default settings, key parameters of the sampling protocols were explored. The performance of the computational protocols was assessed via (i) the reproduction of the X-ray bioactive structures, (ii) the size, coverage and diversity of the output conformational ensembles, (iii) the compactness/extendedness of the conformers, and (iv) the ability to locate the global energy minimum. The influence of the stochastic nature of the searches on the results was also examined. Much better results were obtained by adopting search parameters enhanced over the default settings, while maintaining computational tractability. In MOE, the recent LowModeMD emerged as the method of choice. Mixed torsional/low-mode from MacroModel performed as well as LowModeMD, and MD/LLMOD performed well for macrocycles. The low-mode based approaches yielded very encouraging results with the flexible and macrocycle sets. Thus, one can productively tackle the computational conformational search of larger flexible compounds for drug discovery, including macrocycles. Copyright © 2013 Elsevier Ltd. All

  2. Tackling Targets.

    ERIC Educational Resources Information Center

    Further Education Unit, London (England).

    This document is designed to help British training and enterprise councils (TECs) and further education (FE) colleges develop and implement strategies for achieving the National Targets for Education and Training (NTET), which were developed by the Confederation of British Industry in 1992 and endorsed by the British government. The findings from…

  3. Tackling Underperformance

    ERIC Educational Resources Information Center

    Mathews, Jay

    2006-01-01

    This article profiles Principal of the Year Mel Riddile, a former University of North Carolina football linebacker and principal of J. E. B. Stuart High school in Fairfax County, Virginia. Riddile was recently named the national high school principal of the year by the National Association of Secondary School Principals (NASSP) and MetLife.…

  4. Group problems in problem-based learning.

    PubMed

    Hendry, Graham D; Ryan, Greg; Harris, Jennifer

    2003-11-01

    Successful small-group learning in problem-based learning (PBL) educational programmes relies on functional group processes. However, there has been limited research on PBL group problems, and no studies have been conducted on problems as perceived by both students and tutors in the same educational context. The authors investigated PBL group problems in a graduate-entry medical programme, and report the most common group problems, and those that hinder students' learning the most. The possible causes of individual quietness and dominant behaviour, and potential influences that group problems may have on the tutorial process are summarized in an exploratory model of PBL group dysfunction that could be used to guide further research. Specifically, there is a need for further evidence on which to base guidelines for tutors and students to effectively manage group problems.

  5. Robust parallel iterative solvers for linear and least-squares problems, Final Technical Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Saad, Yousef

    2014-01-16

    the problem of evaluating f(A)v which arises in statistical sampling. 11. As an application to the methods we developed, we tackled the problem of computing the diagonal of the inverse of a matrix. This arises in statistical applications as well as in many applications in physics. We explored probing methods as well as domain-decomposition type methods. 12. A collaboration with researchers from Toulouse, France, considered the important problem of computing the Schur complement in a domain-decomposition approach. 13. We explored new ways of preconditioning linear systems, based on low-rank approximations.« less

  6. Pavement markings and safety : tech transfer summary.

    DOT National Transportation Integrated Search

    2010-11-01

    Objective: This study explores the statistical relationship between crash occurrence probability and longitudinal pavement marking retroreflectivity. : Problem Statement: Previous research on pavement markings, from a safety perspective, tackled vari...

  7. Persuading Students To Care.

    ERIC Educational Resources Information Center

    Young, Jeffrey R.

    2003-01-01

    Describes how Eugene M. Lang, a philanthropist known for tackling large problems in education, is financing Project Pericles to encourage colleges to promote civic-mindedness among their students. (EV)

  8. Exploring Student and Supervisor Interaction during the SciPro Thesis Process: Two Use Cases

    ERIC Educational Resources Information Center

    Hansen, Preben; Hansson, Henrik

    2017-01-01

    Common problems identified by students during their interaction with supervisors are too little instructions as well as infrequent and insufficient supervisor feedback. The SciPro system has been developed to tackle these problems. This paper describes, analyzes and discusses the interaction between students and supervisors using the SciPro…

  9. Erosion problems in Alexandroupolis coastline, North-Eastern Greece

    NASA Astrophysics Data System (ADS)

    Xeidakis, G. S.; Delimani, P.; Skias, S.

    2007-12-01

    This paper deals with the coastal erosion processes and the related problems around the city of Alexandroupolis, NE Aegean Sea, N. Greece. The area is very fast developing, as the city is an important port and a summer resort center in SE Balkans, and will become soon a transportation and energy center, as well. The coastline under study exhibits an east west orientation and has a length of more than 50 km. The spatial distribution and the characteristics of the changes in the shoreline were studied by comparing old and new air photographs and topographic maps, as well as through repeated series of field observations and local measurements regarding the erosion process. From these studies it was concluded that the greater stretch of the western part of the coast, under consideration, is of moderate to high relief, with a considerable participation of coastal cliffs. It consists of conglomerates of varying granulometry and consistency and is under moderate to severe erosion process. The erosion phenomena in the western part of the coast may be attributed, primarily, to strong S, SW winds, blowing in the area and to trapping of sediments by Alexandroupolis’ port breakwaters; the port stops or/and diverts the sediments to the open sea; and to the east to west longshore sea current, prevailing in the area. The eastern stretch of the coast is a plain area, formed by sandy silty sediments; being a part of the river Evros’ Delta, it is under deposition and accretes seawards. The majority of the coasts under consideration are classified as coasts of high wave energy potential. Hard structures, as shore protection measures, have been constructed in some places, but they were proved, in rather short time-period, ineffective and suffered extensive failures. Thus, it is argued that for a long-term cost-effective tackling of the various erosion problems on any stretch, priority must be given to soft engineering measures; although, certain hard measures, carefully selected

  10. Fast Parallel Molecular Algorithms for DNA-Based Computation: Solving the Elliptic Curve Discrete Logarithm Problem over GF(2n)

    PubMed Central

    Li, Kenli; Zou, Shuting; Xv, Jin

    2008-01-01

    Elliptic curve cryptographic algorithms convert input data to unrecognizable encryption and the unrecognizable data back again into its original decrypted form. The security of this form of encryption hinges on the enormous difficulty that is required to solve the elliptic curve discrete logarithm problem (ECDLP), especially over GF(2n), n ∈ Z+. This paper describes an effective method to find solutions to the ECDLP by means of a molecular computer. We propose that this research accomplishment would represent a breakthrough for applied biological computation and this paper demonstrates that in principle this is possible. Three DNA-based algorithms: a parallel adder, a parallel multiplier, and a parallel inverse over GF(2n) are described. The biological operation time of all of these algorithms is polynomial with respect to n. Considering this analysis, cryptography using a public key might be less secure. In this respect, a principal contribution of this paper is to provide enhanced evidence of the potential of molecular computing to tackle such ambitious computations. PMID:18431451

  11. Evaluation of the “Eat Better Feel Better” Cooking Programme to Tackle Barriers to Healthy Eating

    PubMed Central

    Garcia, Ada L.; Reardon, Rebecca; Hammond, Elizabeth; Parrett, Alison; Gebbie-Diben, Anne

    2017-01-01

    We evaluated a 6-week community-based cooking programme, “Eat Better Feel Better”, aimed at tackling barriers to cooking and healthy eating using a single-group repeated measures design. 117 participants enrolled, 62 completed baseline and post-intervention questionnaires, and 17 completed these and a 3–4 months follow-up questionnaire. Most participants were female, >45 years, and socioeconomically deprived. Confidence constructs changed positively from baseline to post-intervention (medians, scale 1 “not confident” to 7 “very confident”): “cooking using raw ingredients” (4, 6 p < 0.003), “following simple recipe” (5, 6 p = 0.003), “planning meals before shopping” (4, 5 p = <0.001), “shopping on a budget (4, 5 p = 0.044), “shopping healthier food” (4, 5 p = 0.007), “cooking new foods” (3, 5 p < 0.001), “cooking healthier foods” (4, 5 p = 0.001), “storing foods safely” (5, 6 p = 0.002); “using leftovers” (4, 5 p = 0.002), “cooking raw chicken” (5, 6 p = 0.021), and “reading food labels” (4, 5 p < 0.001). “Microwaving ready-meals” decreased 46% to 39% (p = 0.132). “Preparing meals from scratch” increased 48% to 59% (p = 0.071). Knowledge about correct portion sizes increased 47% to 74% (p = 0.002). Spending on ready-meals/week decreased. Follow-up telephone interviewees (n = 42) reported developing healthier eating patterns, spending less money/wasting less food, and preparing more meals/snacks from raw ingredients. The programme had positive effects on participants’ cooking skills confidence, helped manage time, and reduced barriers of cost, waste, and knowledge. PMID:28375186

  12. How to tackle the problem early? The role of education in the prevention of obesity.

    PubMed

    Dietz, W

    1999-05-01

    The major issues that confront the clinician in relation to childhood obesity are identifying children at risk, deciding the goal and focus of therapy, and determining how to maintain weight loss. The severity of obesity and the age at which it is present appear to be significant determinants of whether childhood obesity will persist into adulthood. At any age, severe obesity is more likely to persist, and obesity present in adolescents is much more likely to persist than obesity in young children. If a child has obese parents, the risk that their obesity will persist to adulthood increases, though the magnitude of that risk varies with the age of the child. The goals of therapy depend on the child's age and the severity of obesity-related complications. Assessment of the family's readiness to change represents the first focus of therapy. A reduction in time spent watching television, coupled with family involvement and a diet that aims to reduce or eliminate high caloric density foods is the best approach in most cases. Children or adolescents who have an emergent complication of obesity are candidates for aggressive weight reduction such as the protein modified fast. More aggressive therapies, such as drug therapy or gastric bypass surgery, must be considered as experimental in children and adolescents.

  13. Connes' embedding problem and Tsirelson's problem

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Junge, M.; Palazuelos, C.; Navascues, M.

    2011-01-15

    We show that Tsirelson's problem concerning the set of quantum correlations and Connes' embedding problem on finite approximations in von Neumann algebras (known to be equivalent to Kirchberg's QWEP conjecture) are essentially equivalent. Specifically, Tsirelson's problem asks whether the set of bipartite quantum correlations generated between tensor product separated systems is the same as the set of correlations between commuting C{sup *}-algebras. Connes' embedding problem asks whether any separable II{sub 1} factor is a subfactor of the ultrapower of the hyperfinite II{sub 1} factor. We show that an affirmative answer to Connes' question implies a positive answer to Tsirelson's. Conversely,more » a positive answer to a matrix valued version of Tsirelson's problem implies a positive one to Connes' problem.« less

  14. Sustainable Schools through Science Across the World

    ERIC Educational Resources Information Center

    Cutler, Marianne

    2007-01-01

    Children need new skills if they are to become part of the solution to challenges such as climate change rather than part of the problem. So states the UK's National Framework for Sustainable Schools. Skills include expressing points of view, weighing up evidence, cooperating, thinking critically, tackling real problems, participating in…

  15. Live Action Role Play and the Development of Teacher Competences: Evaluation of "Everyday Life in the Classroom"

    ERIC Educational Resources Information Center

    Imhof, Margarete; Starker, Ulrike; Spaude, Elena

    2016-01-01

    Building on Dörner's (1996) theory of complex problem-solving, a learning scenario for teacher students was created and tested. Classroom management is interpreted as a complex problem, which requires the integration of competing interests and tackling multiple, simultaneous tasks under time pressure and with limited information. In addition,…

  16. Inviting Uncertainty into the Classroom

    ERIC Educational Resources Information Center

    Beghetto, Ronald A.

    2017-01-01

    Most teachers try to avoid having students experience uncertainty in their schoolwork. But if we want to prepare students to tackle complex problems (and the uncertainty that accompanies such problems), we must give them learning experiences that involve feeling unsure and sometimes even confused. Beghetto presents five strategies that help…

  17. Marshak Lectureship Talk: Women in Physics in the Baltic States Region: Problems and Solutions

    NASA Astrophysics Data System (ADS)

    Satkovskiene, Dalia

    2008-03-01

    formulated. As changing the stereotypes is long lasting process it was decided firstly to concentrate strategy implementation plans on changes in science management policy tackling the problem from the top and allowing receive the most quick results. For this we created the regional Baltic States Network among the corresponding international women working groups, professional organizations (Scientific societies) and corresponding departments of the governmental institutions. BASNET also became a full member of European Platform of Women Scientists (EPWS)-prestige women organization signally influencing the European Community science policy.

  18. Coordinative Voltage Control Strategy with Multiple Resources for Distribution Systems of High PV Penetration: Preprint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhu, Xiangqi; Zhang, Yingchen

    This paper presents an optimal voltage control methodology with coordination among different voltage-regulating resources, including controllable loads, distributed energy resources such as energy storage and photovoltaics (PV), and utility voltage-regulating devices such as voltage regulators and capacitors. The proposed methodology could effectively tackle the overvoltage and voltage regulation device distortion problems brought by high penetrations of PV to improve grid operation reliability. A voltage-load sensitivity matrix and voltage-regulator sensitivity matrix are used to deploy the resources along the feeder to achieve the control objectives. Mixed-integer nonlinear programming is used to solve the formulated optimization control problem. The methodology has beenmore » tested on the IEEE 123-feeder test system, and the results demonstrate that the proposed approach could actively tackle the voltage problem brought about by high penetrations of PV and improve the reliability of distribution system operation.« less

  19. Examining the cost effectiveness of interventions to promote the physical health of people with mental health problems: a systematic review

    PubMed Central

    2013-01-01

    Background Recently attention has begun to focus not only on assessing the effectiveness of interventions to tackle mental health problems, but also on measures to prevent physical co-morbidity. Individuals with mental health problems are at significantly increased risk of chronic physical health problems, such as cardiovascular disease or diabetes, as well as reduced life expectancy. The excess costs of co-morbid physical and mental health problems are substantial. Potentially, measures to reduce the risk of co-morbid physical health problems may represent excellent value for money. Methods To conduct a systematic review to determine what is known about economic evaluations of actions to promote better physical health in individuals identified as having a clinically diagnosed mental disorder, but no physical co-morbidity. Systematic searches of databases were supplemented by hand searches of relevant journals and websites. Results Of 1970 studies originally assessed, 11 met our inclusion criteria. In addition, five protocols for other studies were also identified. Studies looked at exercise programmes, nutritional advice, smoking, alcohol and drug cessation, and reducing the risk of blood borne infectious diseases such as HIV/AIDS and hepatitis. All of the lifestyle and smoking cessation studies focused on people with depression and anxiety disorders. Substance abuse and infectious disease prevention studies focused on people with psychoses and bipolar disorder. Conclusions There is a very small, albeit growing, literature on the cost effectiveness of interventions to promote the physical health of people with mental health problems. Most studies suggest that value for money actions in specific contexts and settings are available. Given that the success or failure of health promoting interventions can be very context specific, more studies are needed in more settings, focused on different population groups with different mental health problems and reporting

  20. Examining the cost effectiveness of interventions to promote the physical health of people with mental health problems: a systematic review.

    PubMed

    Park, A-La; McDaid, David; Weiser, Prisca; Von Gottberg, Carolin; Becker, Thomas; Kilian, Reinhold

    2013-08-29

    Recently attention has begun to focus not only on assessing the effectiveness of interventions to tackle mental health problems, but also on measures to prevent physical co-morbidity. Individuals with mental health problems are at significantly increased risk of chronic physical health problems, such as cardiovascular disease or diabetes, as well as reduced life expectancy. The excess costs of co-morbid physical and mental health problems are substantial. Potentially, measures to reduce the risk of co-morbid physical health problems may represent excellent value for money. To conduct a systematic review to determine what is known about economic evaluations of actions to promote better physical health in individuals identified as having a clinically diagnosed mental disorder, but no physical co-morbidity. Systematic searches of databases were supplemented by hand searches of relevant journals and websites. Of 1970 studies originally assessed, 11 met our inclusion criteria. In addition, five protocols for other studies were also identified. Studies looked at exercise programmes, nutritional advice, smoking, alcohol and drug cessation, and reducing the risk of blood borne infectious diseases such as HIV/AIDS and hepatitis. All of the lifestyle and smoking cessation studies focused on people with depression and anxiety disorders. Substance abuse and infectious disease prevention studies focused on people with psychoses and bipolar disorder. There is a very small, albeit growing, literature on the cost effectiveness of interventions to promote the physical health of people with mental health problems. Most studies suggest that value for money actions in specific contexts and settings are available. Given that the success or failure of health promoting interventions can be very context specific, more studies are needed in more settings, focused on different population groups with different mental health problems and reporting intermediate and long term outcomes. There is

  1. A Mixed Integer Efficient Global Optimization Framework: Applied to the Simultaneous Aircraft Design, Airline Allocation and Revenue Management Problem

    NASA Astrophysics Data System (ADS)

    Roy, Satadru

    Traditional approaches to design and optimize a new system, often, use a system-centric objective and do not take into consideration how the operator will use this new system alongside of other existing systems. This "hand-off" between the design of the new system and how the new system operates alongside other systems might lead to a sub-optimal performance with respect to the operator-level objective. In other words, the system that is optimal for its system-level objective might not be best for the system-of-systems level objective of the operator. Among the few available references that describe attempts to address this hand-off, most follow an MDO-motivated subspace decomposition approach of first designing a very good system and then provide this system to the operator who decides the best way to use this new system along with the existing systems. The motivating example in this dissertation presents one such similar problem that includes aircraft design, airline operations and revenue management "subspaces". The research here develops an approach that could simultaneously solve these subspaces posed as a monolithic optimization problem. The monolithic approach makes the problem a Mixed Integer/Discrete Non-Linear Programming (MINLP/MDNLP) problem, which are extremely difficult to solve. The presence of expensive, sophisticated engineering analyses further aggravate the problem. To tackle this challenge problem, the work here presents a new optimization framework that simultaneously solves the subspaces to capture the "synergism" in the problem that the previous decomposition approaches may not have exploited, addresses mixed-integer/discrete type design variables in an efficient manner, and accounts for computationally expensive analysis tools. The framework combines concepts from efficient global optimization, Kriging partial least squares, and gradient-based optimization. This approach then demonstrates its ability to solve an 11 route airline network

  2. Single-molecule fluorescence microscopy review: shedding new light on old problems

    PubMed Central

    Shashkova, Sviatlana

    2017-01-01

    Fluorescence microscopy is an invaluable tool in the biosciences, a genuine workhorse technique offering exceptional contrast in conjunction with high specificity of labelling with relatively minimal perturbation to biological samples compared with many competing biophysical techniques. Improvements in detector and dye technologies coupled to advances in image analysis methods have fuelled recent development towards single-molecule fluorescence microscopy, which can utilize light microscopy tools to enable the faithful detection and analysis of single fluorescent molecules used as reporter tags in biological samples. For example, the discovery of GFP, initiating the so-called ‘green revolution’, has pushed experimental tools in the biosciences to a completely new level of functional imaging of living samples, culminating in single fluorescent protein molecule detection. Today, fluorescence microscopy is an indispensable tool in single-molecule investigations, providing a high signal-to-noise ratio for visualization while still retaining the key features in the physiological context of native biological systems. In this review, we discuss some of the recent discoveries in the life sciences which have been enabled using single-molecule fluorescence microscopy, paying particular attention to the so-called ‘super-resolution’ fluorescence microscopy techniques in live cells, which are at the cutting-edge of these methods. In particular, how these tools can reveal new insights into long-standing puzzles in biology: old problems, which have been impossible to tackle using other more traditional tools until the emergence of new single-molecule fluorescence microscopy techniques. PMID:28694303

  3. Problem-Framing: A perspective on environmental problem-solving

    NASA Astrophysics Data System (ADS)

    Bardwell, Lisa V.

    1991-09-01

    The specter of environmental calamity calls for the best efforts of an involved public. Ironically, the way people understand the issues all too often serves to discourage and frustrate rather than motivate them to action. This article draws from problem-solving perspectives offered by cognitive psychology and conflict management to examine a framework for thinking about environmental problems that promises to help rather than hinder efforts to address them. Problem-framing emphasizes focusing on the problem definition. Since how one defines a problem determines one's understanding of and approach to that problem, being able to redefine or reframe a problem and to explore the “problem space” can help broaden the range of alternatives and solutions examined. Problem-framing incorporates a cognitive perspective on how people respond to information. It explains why an emphasis on problem definition is not part of people's typical approach to problems. It recognizes the importance of structure and of having ways to organize that information on one's problem-solving effort. Finally, problem-framing draws on both cognitive psychology and conflict management for strategies to manage information and to create a problem-solving environment that not only encourages participation but can yield better approaches to our environmental problems.

  4. Are Your Students Problem Performers or Problem Solvers?

    ERIC Educational Resources Information Center

    Barlow, Angela T.; Duncan, Matthew; Lischka, Alyson E.; Hartland, Kristin S.; Willingham, J. Christopher

    2017-01-01

    When presented with a problem in mathematics class, students often function as problem performers rather than problem solvers (Rigelman 2007). That is, rather than understanding the problem, students focus on using an operation to complete it. Students' tendencies to act as problem performers can prevent them from suggesting problem-solving…

  5. Forced Convection Heat Transfer in Circular Pipes

    ERIC Educational Resources Information Center

    Tosun, Ismail

    2007-01-01

    One of the pitfalls of engineering education is to lose the physical insight of the problem while tackling the mathematical part. Forced convection heat transfer (the Graetz-Nusselt problem) certainly falls into this category. The equation of energy together with the equation of motion leads to a partial differential equation subject to various…

  6. Collection and curation of IDPs in the stratosphere and below. Part 2: The Greenland and Antarctic ice sheets

    NASA Technical Reports Server (NTRS)

    Maurette, Michel; Hammer, C.; Harvey, R.; Immel, G.; Kurat, G.; Taylor, S.

    1994-01-01

    In a companion paper, Zolensky discusses interplanetary dust particles (IDP's) collected in the stratosphere. Here, we describe the recovery of much larger unmelted to partially melted IDP's from the Greenland and Antarctica ice sheet, and discuss problems arising in their collection and curation, as well as future prospects for tackling these problems.

  7. Teachers' Perspectives on Effective Responses to Overt Bullying

    ERIC Educational Resources Information Center

    Sokol, Nicole; Bussey, Kay; Rapee, Ronald M.

    2016-01-01

    School communities worldwide are tackling the pervasive problem of school bullying. Teachers hold an important responsibility to prevent and manage bullying problems in the school environment and often play a key role in advising students about how to respond to bullying. This study examined teachers' perspectives on the most effective ways to…

  8. Enhancing chemistry problem-solving achievement using problem categorization

    NASA Astrophysics Data System (ADS)

    Bunce, Diane M.; Gabel, Dorothy L.; Samuel, John V.

    The enhancement of chemistry students' skill in problem solving through problem categorization is the focus of this study. Twenty-four students in a freshman chemistry course for health professionals are taught how to solve problems using the explicit method of problem solving (EMPS) (Bunce & Heikkinen, 1986). The EMPS is an organized approach to problem analysis which includes encoding the information given in a problem (Given, Asked For), relating this to what is already in long-term memory (Recall), and planning a solution (Overall Plan) before a mathematical solution is attempted. In addition to the EMPS training, treatment students receive three 40-minute sessions following achievement tests in which they are taught how to categorize problems. Control students use this time to review the EMPS solutions of test questions. Although problem categorization is involved in one section of the EMPS (Recall), treatment students who received specific training in problem categorization demonstrate significantly higher achievement on combination problems (those problems requiring the use of more than one chemical topic for their solution) at (p = 0.01) than their counterparts. Significantly higher achievement for treatment students is also measured on an unannounced test (p = 0.02). Analysis of interview transcripts of both treatment and control students illustrates a Rolodex approach to problem solving employed by all students in this study. The Rolodex approach involves organizing equations used to solve problems on mental index cards and flipping through them, matching units given when a new problem is to be solved. A second phenomenon observed during student interviews is the absence of a link in the conceptual understanding of the chemical concepts involved in a problem and the problem-solving skills employed to correctly solve problems. This study shows that explicit training in categorization skills and the EMPS can lead to higher achievement in complex problem

  9. Bois Forte Indoor Air Quality Program

    EPA Pesticide Factsheets

    The Bois Forte Indoor Air Quality Program acted swiftly and aggressively to tackle mold and moisture problems in its community members’ homes after several residents became ill as a result of environmental exposures.

  10. The Navajo Nation Radon Program

    EPA Pesticide Factsheets

    The Bois Forte Indoor Air Quality Program acted swiftly and aggressively to tackle mold and moisture problems in its community members’ homes after several residents became ill as a result of environmental exposures.

  11. A Methodology For Measuring Resilience in a Satellite-Based Communication Network

    DTIC Science & Technology

    2014-03-27

    solving the Travelling Salesman Problem (TSP) (Solnon p. 1). Based upon swarm intelligence, in a travelling salesman problem ants are sent out from...developed for the Travelling Salesman Problem (TSP) in 1992 (Solnon p. 1), this metaheuristic shows its roots in the original formulations. Given v, the...is lost. To tackle this problem , a common LEO orbit type is examined, the polar orbit. Polar LEO satellites travel from the south pole to the

  12. Class and Home Problems: Optimization Problems

    ERIC Educational Resources Information Center

    Anderson, Brian J.; Hissam, Robin S.; Shaeiwitz, Joseph A.; Turton, Richard

    2011-01-01

    Optimization problems suitable for all levels of chemical engineering students are available. These problems do not require advanced mathematical techniques, since they can be solved using typical software used by students and practitioners. The method used to solve these problems forces students to understand the trends for the different terms…

  13. A Non-Perturbative Treatment of Quantum Impurity Problems in Real Lattices

    NASA Astrophysics Data System (ADS)

    Allerdt, Andrew C.

    Historically, the RKKY or indirect exchange, interaction has been accepted as being able to be described by second order perturbation theory. A typical universal expression is usually given in this context. This approach, however, fails to incorporate many body effects, quantum fluctuations, and other important details. In Chapter 2, a novel numerical approach is developed to tackle these problems in a quasi-exact, non-perturbative manner. Behind the method lies the main concept of being able to exactly map an n-dimensional lattice problem onto a 1-dimensional chain. The density matrix renormalization group algorithm is then employed to solve the newly cast Hamiltonian. In the following chapters, it is demonstrated that conventional RKKY theory does not capture the crucial physics. It is found that the Kondo effect, i.e. the screening of an impurity spin, tends to dominate over a ferromagnetic interaction between impurity spins. Furthermore, it is found that the indirect exchange interaction does not decay algebraically. Instead, there is a crossover upon increasing JK, where impurities favor forming their own independent Kondo states after just a few lattice spacings. This is not a trivial result, as one may naively expect impurities to interact when their conventional Kondo clouds overlap. The spin structure around impurities coupled to the edge of a 2D topological insulator is investigated in Chapter 7. Modeled after materials such as silicine, germanene, and stanene, it is shown with spatial resolution of the lattice that the specific impurity placement plays a key role. Effects of spin-orbit interactions are also discussed. Finally, in the last chapter, transition metal complexes are studied. This really shows the power and versatility of the method developed throughout the work. The spin states of an iron atom in the molecule FeN4C 10 are calculated and compared to DFT, showing the importance of inter-orbital coulomb interactions. Using dynamical DMRG, the

  14. "The Only Problem Is, Children Will Like Their Chips": Education and the Discursive Production of Ill-Health

    ERIC Educational Resources Information Center

    Evans, John; Evans, Bethan; Rich, Emma

    2003-01-01

    On 16 January 2002, the United Kingdom House of Commons Select Committee published a report entitled "Tackling Obesity in England". Drawing on insights from the work of Bernstein, Bourdieu and Foucault, this article will suggest that the report provides an example "par excellence" of the way in which "the body" (our…

  15. Confusing Aspects in the Calculation of the Electrostatic Potential of an Infinite Line of Charge

    ERIC Educational Resources Information Center

    Jimenez, J. L.; Campos, I.; Roa-Neri, J. A. E.

    2012-01-01

    In this work we discuss the trick of eliminating infinite potential of reference arguing that it corresponds to a constant of integration, in the problem of determining the electrostatic potential of an infinite line of charge with uniform density, and show how the problem must be tackled properly. The usual procedure is confusing for most…

  16. A Study of the Spelling Errors Committed by Students of English in Saudi Arabia: Exploration and Remedial Measures

    ERIC Educational Resources Information Center

    Hameed, Paikar Fatima Mazhar

    2016-01-01

    The craziness of English spelling has undeniably perplexed learners, especially in an EFL context as in the Kingdom of Saudi Arabia. In these situations, among other obstacles, learners also have to tackle the perpetual and unavoidable problem of MT interference. Sadly, this perplexity takes the shape of a real problem in the language classroom…

  17. Evaluating the Relevance of Educational Videos Using BKT and Big Data

    ERIC Educational Resources Information Center

    MacHardy, Zachary; Pardos, Zachary A.

    2015-01-01

    Along with the advent of MOOCs and other online learning platforms such as Khan Academy, the role of online education has continued to grow in relation to that of traditional on-campus instruction. Rather than tackle the problem of evaluating large educational units such as entire online courses, this paper approaches a smaller problem: exploring…

  18. Community How To Guide On Underage Drinking Prevention: Coalition Building.

    ERIC Educational Resources Information Center

    National Association of Governors' Highway Safety Representatives.

    Coalitions have been used successfully in the United States to tackle a number of seemingly intractable problems. For communities that want to reduce their underage drinking problem, putting together a broad-based coalition can bring substantial dividends. In this guide, readers will learn the steps that bring together a diverse group of people in…

  19. Finite element solution of nonlinear eddy current problems with periodic excitation and its industrial applications☆

    PubMed Central

    Bíró, Oszkár; Koczka, Gergely; Preis, Kurt

    2014-01-01

    An efficient finite element method to take account of the nonlinearity of the magnetic materials when analyzing three-dimensional eddy current problems is presented in this paper. The problem is formulated in terms of vector and scalar potentials approximated by edge and node based finite element basis functions. The application of Galerkin techniques leads to a large, nonlinear system of ordinary differential equations in the time domain. The excitations are assumed to be time-periodic and the steady-state periodic solution is of interest only. This is represented either in the frequency domain as a finite Fourier series or in the time domain as a set of discrete time values within one period for each finite element degree of freedom. The former approach is the (continuous) harmonic balance method and, in the latter one, discrete Fourier transformation will be shown to lead to a discrete harmonic balance method. Due to the nonlinearity, all harmonics, both continuous and discrete, are coupled to each other. The harmonics would be decoupled if the problem were linear, therefore, a special nonlinear iteration technique, the fixed-point method is used to linearize the equations by selecting a time-independent permeability distribution, the so-called fixed-point permeability in each nonlinear iteration step. This leads to uncoupled harmonics within these steps. As industrial applications, analyses of large power transformers are presented. The first example is the computation of the electromagnetic field of a single-phase transformer in the time domain with the results compared to those obtained by traditional time-stepping techniques. In the second application, an advanced model of the same transformer is analyzed in the frequency domain by the harmonic balance method with the effect of the presence of higher harmonics on the losses investigated. Finally a third example tackles the case of direct current (DC) bias in the coils of a single-phase transformer. PMID

  20. The adiabatic piston: a perpetuum mobile in the mesoscopic realm

    NASA Astrophysics Data System (ADS)

    Crosignani, Bruno; Porto, Paolo; Conti, Claudio

    2004-03-01

    A detailed analysis of the adiabatic-piston problem reveals, for a finely-tuned choice of the spatial dimensions of the system, peculiar dynamical features that challenge the statement that an isolated system necessarily reaches a time-independent equilibrium state. In particular, the piston behaves like a perpetuum mobile, i.e., it never comes to a stop but keeps wandering, undergoing sizeable oscillations around the position corresponding to maximum entropy; this has remarkable implications on the entropy changes of a mesoscopic isolated system and on the limits of validity of the second law of thermodynamics in the mesoscopic realm.

  1. Weighty Issues for Kids: Taking Aim at Childhood Obesity

    MedlinePlus

    ... Weighty Issues for Kids Taking Aim at Childhood Obesity Send us your comments Kids face a lot ... of lifelong medical conditions. That problem is childhood obesity. Kids won’t be able to tackle this ...

  2. Is EIA part of the wind power planning problem?

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smart, Duncan Ewan; Stojanovic, Timothy A., E-mail: tas21@st-andrews.ac.uk; Warren, Charles R.

    2014-11-15

    This research evaluates the importance and effectiveness of Environmental Impact Assessment (EIA) within wind farm planning debates, drawing on insights from case studies in Scotland. Despite general public support for renewable energy on the grounds that it is needed to tackle climate change and implement sustainable development, many proposed wind farms encounter significant resistance. The importance of planning issues and (EIA) processes has arguably been overlooked within recent wind farm social acceptability discourse. Through semi-structured interviews with key stakeholders and textual analysis of EIA documents, the characteristics of EIA are assessed in terms of its perceived purpose and performance. Themore » data show that whilst respondents perceive EIA to be important, they express concerns about bias and about the inability of EIA to address climate change and wind farm decommissioning issues adequately. Furthermore, the research identifies key issues which impede the effectiveness of EIA, and reveals differences between theoretical and practical framings of EIA. The paper questions the assumption that EIA is a universally applicable tool, and argues that its effectiveness should be analysed in the context of specific development sectors. The article concludes by reviewing whether the recently amended EIA Directive (2014/52/EU) could resolve identified problems within national EIA practice. - Highlights: • Evaluation of EIA for onshore wind farm planning in Scotland. • EIA is important for multiple aspects of onshore wind farm planning. • Multiple substantive deficiencies of relevance to wind farm planning exist in EIA. • Further research into EIA effectiveness for specific development types is required. • Directive 2014/52/EU may improve EIA effectiveness within wind farm planning.« less

  3. The interactive effect of paternal problem drinking and maternal problem drinking on adolescent internalizing problems.

    PubMed

    Ohannessian, Christine McCauley

    2015-11-01

    This study examined the effects of both paternal problem drinking and maternal problem drinking on adolescent internalizing problems (depression and anxiety symptomatology). Surveys were administered to 566 10th and 11th grade students from the Mid-Atlantic region of the U.S. in the spring of 2007 and again in the spring of 2008. Although significant main effects were not observed, significant interactions were found between paternal problem drinking and maternal problem drinking for internalizing problems, especially for boys. In general, these interactions indicated that when paternal problem drinking was high, depression symptomatology and anxiety symptomatology were lower if maternal problem drinking was low. Findings from this study highlight the need to consider both paternal and maternal problem drinking when examining the effects that parental problem drinking may have on adolescent adjustment. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. News Festival: Science on stage deadline approaches Conference: Welsh conference attracts teachers Data: New phase of CERN openlab tackles exascale IT challenges for science Meeting: German Physical Society holds its physics education spring meeting Conference: Association offers golden opportunity in Norway Competition: So what's the right answer then?

    NASA Astrophysics Data System (ADS)

    2012-07-01

    Festival: Science on stage deadline approaches Conference: Welsh conference attracts teachers Data: New phase of CERN openlab tackles exascale IT challenges for science Meeting: German Physical Society holds its physics education spring meeting Conference: Association offers golden opportunity in Norway Competition: So what's the right answer then?

  5. Impact of Migraine on School Performance

    MedlinePlus

    ... Spencer, MD Steven Karceski, MD The impact of migraine on school performance Daniel Kantor, MD e168 WHAT ... this study tackle an often overlooked problem: how migraine headache affects the school performance of children. 1 ...

  6. Traffic safety issues in North Dakota : phase II : driver knowledge, attitude, behavior and beliefs : focus group : young male drivers

    DOT National Transportation Integrated Search

    2008-10-01

    Traffic safety is a widespread social concern. Tackling the problem requires understanding the people : who are driving. This includes information about driver behavior, but also about perceptions these drivers : hold regarding their driving. North D...

  7. A Mind-Set Is a Difficult Thing to Change: Why Reforming Low-Performing Schools Requires Eradicating Negative Beliefs about Students. The Claremont Letter. Volume 2, Issue 3

    ERIC Educational Resources Information Center

    Thompson, Gail

    2007-01-01

    Numerous researchers have devoted their careers to school reform. At the same time, many politicians have gotten elected by promising to fix failing schools. Although a lot of time, energy, and money have been invested in tackling this problem, the problem persists: Too many schools in the United States are failing to prepare too many students for…

  8. Guidance in the Secondary School

    ERIC Educational Resources Information Center

    Kumar, V. Jurist Lional

    2010-01-01

    Secondary School Students face a lot of problems in their body as well as in mind due to puberty that tends to adolescence stage. Adolescence has peculiar characters of their own. They need proper Guidance and Counselling to tackle their own problems. Guidance is described as a counselling service to assist the individual in achieving self…

  9. The Mountain Invasion Research Network (MIREN): Linking Local and Global Scales for Addressing an Ecological Consequence of Global Change

    Treesearch

    Christoph Kueffer; Curtis Daehler; Hansjörg Dietz; Keith McDougall; Catherine Parks; Aníbal Pauchard; Lisa Rew

    2014-01-01

    Many modern environmental problems span vastly different spatial scales, from the management of local ecosystems to understanding globally interconnected processes, and addressing them through international policy. MIREN tackles one such “glocal” (global/local) environmental problem – plant invasions in mountains – through a transdisciplinary, multi-scale learning...

  10. All in a Knot of One Another's Labours: Self-Determination, Network Organising and Learning

    ERIC Educational Resources Information Center

    Pedler, Mike

    2012-01-01

    This essay is about how to learn to organise to tackle the intractable and most difficult problems of organisations and societies. It opens with a discussion of the nature of such problems, which are the spur for Revans' action learning and the focus of some recent thinking on leadership. Action learning works on the basis of peer relationships…

  11. Searching for Words: One Strategic Use of the Mother Tongue by Advanced Spanish EFL Writers

    ERIC Educational Resources Information Center

    Murphy, Liz; Roca de Larios, Julio

    2010-01-01

    Studies of cognitive processes in SL writing have paid attention to the strategies that writers use to tackle problems in composing. In text-generation, finding lexical items in the L2 to express their meanings is one of the most crucial problems writers have to face, for reasons related to the availability and accessibility of relevant linguistic…

  12. Aiming Talent Development toward Creative Eminence in the 21st Century

    ERIC Educational Resources Information Center

    Olszewski-Kubilius, Paula; Subotnik, Rena F.; Worrell, Frank C.

    2016-01-01

    Much has been written about the social and scientific problems that face the world in the 21st century, including climate change and economic inequality. In this context, the development of talented individuals who can tackle these problems is most important. In this article, the authors discuss the implications of 21st-century challenges for the…

  13. Scientific Computing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fermilab

    2017-09-01

    Scientists, engineers and programmers at Fermilab are tackling today’s most challenging computational problems. Their solutions, motivated by the needs of worldwide research in particle physics and accelerators, help America stay at the forefront of innovation.

  14. 'McDonalds and KFC, it's never going to happen': the challenges of working with food outlets to tackle the obesogenic environment.

    PubMed

    Hanratty, Barbara; Milton, Beth; Ashton, Matthew; Whitehead, Margaret

    2012-12-01

    Food outlets may make an important contribution to an obesogenic environment. This study investigated barriers and facilitators to public health work with food outlets in disadvantaged areas. In-depth qualitative interviews with 36 directors, managers and public health service delivery staff in a coterminous primary care trust and local authority in northwest England. Data were analysed using the constant comparative method. Three interventions were available to engage with businesses; awards for premises that welcomed breastfeeding mothers or offered healthy menu options and local authority planning powers. Sensitivity to the potential conflict between activities that generate profit and those that promote health, led to compromises, such as awards for cafés that offer only one healthy option on an otherwise unhealthy menu. An absence of existing relationships with businesses and limited time were powerful disincentives to action, leading to greater engagement with public rather than private sector organizations. Hiring staff with commercial experience and incentives for businesses were identified as useful strategies, but seldom used. Encouraging food outlets to contribute to tackling the obesogenic environment is a major challenge for local public health teams that requires supportive national policies. Commitment to engage with the local public health service should be part of any national voluntary agreements with industry.

  15. In defense of basic science funding: today's scientific discovery is tomorrow's medical advance.

    PubMed

    Tessier-Lavigne, Marc

    2013-06-01

    In this address, I will discuss the importance of basic science in tackling our health problems. I will also describe how the funding cuts are damaging our economic competitiveness and turning our young people away from science.

  16. Measuring walking and cycling using the PABS (pedestrian and bicycling survey) approach : a low-cost survey method for local communities.

    DOT National Transportation Integrated Search

    2010-12-01

    To tackle the problems of greenhouse gas emissions, traffic congestion, resident quality of life, and public health concerns, communities are using initiatives to spur more walking and cycling. As local governments face hard choices about which progr...

  17. A steady state solution for ditch drainage problem with special reference to seepage face and unsaturated zone flow contribution: Derivation of a new drainage spacing eqaution

    NASA Astrophysics Data System (ADS)

    Yousfi, Ammar; Mechergui, Mohammed

    2016-04-01

    The seepage face is an important feature of the drainage process when recharge occurs to a permeable region with lateral outlets. Examples of the formation of a seepage face above the downstream water level include agricultural land drained by ditches. Flow problem to these drains has been investigated extensively by many researchers (e.g. Rubin, 1968; Hornberger et al. 1969; Verma and Brutsaert, 1970; Gureghian and Youngs, 1975; Vauclin et al., 1975; Skaggs and Tang, 1976; Youngs, 1990; Gureghian, 1981; Dere, 2000; Rushton and Youngs, 2010; Youngs, 2012; Castro-Orgaz et al., 2012) and may be tackled either using variably saturated flow models, or the complete 2-D solution of Laplace equation, or using the Dupuit-Forchheimer approximation; the most widely accepted methods to obtain analytical solutions for unconfined drainage problems. However, the investigation reported by Clement et al. (1996) suggest that accounting for the seepage face alone, as in the fully saturated flow model, does not improve the discharge estimate because of disregarding flow the unsaturated zone flow contribution. This assumption can induce errors in the location of the water table surface and results in an underestimation of the seepage face and the net discharge (e.g. Skaggs and Tang, 1976; Vauclin et al., 1979; Clement et al., 1996). The importance of the flow in the unsaturated zone has been highlighted by many authors on the basis of laboratory experiments and/or numerical experimentations (e.g. Rubin, 1968; Verma and Brutsaert, 1970; Todsen, 1973; Vauclin et al., 1979; Ahmad et al., 1993; Anguela, 2004; Luthin and Day, 1955; Shamsai and Narasimhan, 1991; Wise et al., 1994; Clement et al., 1996; Boufadel et al., 1999; Romano et al., 1999; Kao et al., 2001; Kao, 2002). These studies demonstrate the failure of fully saturated flow models and suggested that the error made when using these models not only depends on soil properties but also on the infiltration rate as reported by Kao et

  18. Fenethylline (Captagon) Abuse - Local Problems from an Old Drug Become Universal.

    PubMed

    Katselou, Maria; Papoutsis, Ioannis; Nikolaou, Panagiota; Qammaz, Samir; Spiliopoulou, Chara; Athanaselis, Sotiris

    2016-08-01

    Fenethylline is a theophylline derivative of amphetamine having stimulant effects similar to those of other amphetamine-type derivatives. Fenethylline was used as medicament for hyperactivity disorders in children, narcolepsy and depression, but it has also been used as a drug of abuse under the common name of 'captagon'. Unlike other drugs of abuse, the clandestine synthesis of fenethylline is simple, using inexpensive laboratory instrumentation and raw materials legal to obtain. A review of all the existing knowledge of fenethylline is reported, concerning its chemistry, synthesis, pharmacology and toxicology, legislation, its prevalence and use as drug of abuse, as well as its analysis in biological or seized samples. Published or reported captagon-related cases and seizures are also presented. All the reviewed information was gathered through a detailed search of PubMed and the Internet. The primary drug market for fenethylline (as captagon) has traditionally been countries located on the Arabian Peninsula but also North Africa since 2013. In Arab countries, millions of captagon tablets are seized every year which represents one-third of global amphetamines seizures within a year. Furthermore, three of four patients treated for drug problems in Saudi Arabia are addicted to amphetamines, almost exclusively in the form of captagon. Significant information on fenethylline is provided for pharmacologists, toxicologists and forensic pathologists. Fenethylline, although old, has recently been introduced to the drug market, especially in Arab countries. Continuous community alertness is needed to tackle this current growing phenomenon. © 2016 Nordic Association for the Publication of BCPT (former Nordic Pharmacological Society).

  19. University Students' Strategies for Constructing Hypothesis when Tackling Paper-and-Pencil Tasks in Physics

    NASA Astrophysics Data System (ADS)

    Guisasola, Jenaro; Ceberio, Mikel; Zubimendi, José Luis

    2006-09-01

    The study we present tries to explore how first year engineering students formulate hypotheses in order to construct their own problem solving structure when confronted with problems in physics. Under the constructivistic perspective of the teaching-learning process, the formulation of hypotheses plays a key role in contrasting the coherence of the students' ideas with the theoretical frame. The main research instrument used to identify students' reasoning is the written report by the student on how they have attempted four problem solving tasks in which they have been asked explicitly to formulate hypotheses. The protocols used in the assessment of the solutions consisted of a semi-quantitative study based on grids designed for the analysis of written answers. In this paper we have included two of the tasks used and the corresponding scheme for the categorisation of the answers. Details of the other two tasks are also outlined. According to our findings we would say that the majority of students judge a hypothesis to be plausible if it is congruent with their previous knowledge without rigorously checking it against the theoretical framework explained in class.

  20. Cloud Computing Techniques for Space Mission Design

    NASA Technical Reports Server (NTRS)

    Arrieta, Juan; Senent, Juan

    2014-01-01

    The overarching objective of space mission design is to tackle complex problems producing better results, and faster. In developing the methods and tools to fulfill this objective, the user interacts with the different layers of a computing system.

  1. AI AND SAR APPROACHES FOR PREDICTING CHEMICAL CARCINOGENICITY: SURVEY AND STATUS REPORT

    EPA Science Inventory

    A wide variety of artificial intelligence (AI) and structure-activity relationship (SAR approaches have been applied to tackling the general problem of predicting rodent chemical carcinogenicity. Given the diversity of chemical structures and mechanisms relative to this endpoin...

  2. Tackling an intractable problem: Can greater taxon sampling help resolve relationships within the Stenopelmatoidea (Orthoptera: Ensifera)?

    USGS Publications Warehouse

    Vandergast, Amy; Weissman, David B; Wood, Dustin; Rentz, David C F; Bazelet, Corinna S; Ueshima, Norihiro

    2017-01-01

    The relationships among and within the families that comprise the orthopteran superfamily Stenopelmatoidea (suborder Ensifera) remain poorly understood. We developed a phylogenetic hypothesis based on Bayesian analysis of two nuclear ribosomal and one mitochondrial gene for 118 individuals (84 de novo and 34 from GenBank). These included Gryllacrididae from North, Central, and South America, South Africa and Madagascar, Australia and Papua New Guinea; Stenopelmatidae from North and Central America and South Africa; Anostostomatidae from North and Central America, Papua New Guinea, New Zealand, Australia, and South Africa; members of the Australian endemic Cooloola (three species); and a representative of Lezina from the Middle East. We also included representatives of all other major ensiferan families: Prophalangopsidae, Rhaphidophoridae, Schizodactylidae, Tettigoniidae, Gryllidae, Gryllotalpidae and Myrmecophilidae and representatives of the suborder Caelifera as outgroups. Bayesian analyses of concatenated sequence data supported a clade of Stenopelmatoidea inclusive of all analyzed members of Gryllacrididae, Stenopelmatidae, Anostostomatidae, Lezina and Cooloola. We found Gryllacrididae worldwide to be monophyletic, while we did not recover a monophyletic Stenopelmatidae nor Anostostomatidae. Australian Cooloola clustered in a clade composed of Australian, New Zealand, and some (but not all) North American Anostostomatidae. Lezina was included in a clade of New World Anostostomatidae. Finally, we compiled and compared karyotypes and sound production characteristics for each supported group. Chromosome number, centromere position, drumming, and stridulation differed among some groups, but also show variation within groups. This preliminary trait information may contribute toward future studies of trait evolution. Despite greater taxon sampling within Stenopelmatoidea than previous efforts, some relationships among the families examined continue to remain elusive.

  3. The a3 problem solving report: a 10-step scientific method to execute performance improvements in an academic research vivarium.

    PubMed

    Bassuk, James A; Washington, Ida M

    2013-01-01

    The purpose of this study was to illustrate the application of A3 Problem Solving Reports of the Toyota Production System to our research vivarium through the methodology of Continuous Performance Improvement, a lean approach to healthcare management at Seattle Children's (Hospital, Research Institute, Foundation). The Report format is described within the perspective of a 10-step scientific method designed to realize measurable improvements of Issues identified by the Report's Author, Sponsor and Coach. The 10-step method (Issue, Background, Current Condition, Goal, Root Cause, Target Condition, Countermeasures, Implementation Plan, Test, and Follow-up) was shown to align with Shewhart's Plan-Do-Check-Act process improvement cycle in a manner that allowed for quantitative analysis of the Countermeasure's outcomes and of Testing results. During fiscal year 2012, 9 A3 Problem Solving Reports were completed in the vivarium under the teaching and coaching system implemented by the Research Institute. Two of the 9 reports are described herein. Report #1 addressed the issue of the vivarium's veterinarian not being able to provide input into sick animal cases during the work day, while report #7 tackled the lack of a standard in keeping track of weekend/holiday animal health inspections. In each Report, a measurable Goal that established the basis for improvement recognition was present. A Five Whys analysis identified the Root Cause for Report #1 as historical work patterns that existed before the veterinarian was hired on and that modern electronic communication tools had not been implemented. The same analysis identified the Root Cause for Report #7 as the vivarium had never standardized the process for weekend/holiday checks. Successful outcomes for both Reports were obtained and validated by robust audit plans. The collective data indicate that vivarium staff acquired a disciplined way of reporting on, as well as solving, problems in a manner consistent with high

  4. Assessing the Quality of Problems in Problem-Based Learning

    ERIC Educational Resources Information Center

    Sockalingam, Nachamma; Rotgans, Jerome; Schmidt, Henk

    2012-01-01

    This study evaluated the construct validity and reliability of a newly devised 32-item problem quality rating scale intended to measure the quality of problems in problem-based learning. The rating scale measured the following five characteristics of problems: the extent to which the problem (1) leads to learning objectives, (2) is familiar, (3)…

  5. Solving the Software Legacy Problem with RISA

    NASA Astrophysics Data System (ADS)

    Ibarra, A.; Gabriel, C.

    2012-09-01

    Nowadays hardware and system infrastructure evolve on time scales much shorter than the typical duration of space astronomy missions. Data processing software capabilities have to evolve to preserve the scientific return during the entire experiment life time. Software preservation is a key issue that has to be tackled before the end of the project to keep the data usable over many years. We present RISA (Remote Interface to Science Analysis) as a solution to decouple data processing software and infrastructure life-cycles, using JAVA applications and web-services wrappers to existing software. This architecture employs embedded SAS in virtual machines assuring a homogeneous job execution environment. We will also present the first studies to reactivate the data processing software of the EXOSAT mission, the first ESA X-ray astronomy mission launched in 1983, using the generic RISA approach.

  6. The effect of problem structure on problem-solving: an fMRI study of word versus number problems.

    PubMed

    Newman, Sharlene D; Willoughby, Gregory; Pruce, Benjamin

    2011-09-02

    It has long been thought that word problems are more difficult to solve than number/equation problems. However, recent findings have begun to bring this broadly believed idea into question. The current study examined the processing differences between these two types of problems. The behavioral results presented here failed to show an overwhelming advantage for number problems. In fact, there were more errors for the number problems than the word problems. The neuroimaging results reported demonstrate that there is significant overlap in the processing of what, on the surface, appears to be completely different problems that elicit different problem-solving strategies. Word and number problems rely on a general network responsible for problem-solving that includes the superior posterior parietal cortex, the horizontal segment of the intraparietal sulcus which is hypothesized to be involved in problem representation and calculation as well as the regions that have been linked to executive aspects of working memory such as the pre-SMA and basal ganglia. While overlap was observed, significant differences were also found primarily in language processing regions such as Broca's and Wernicke's areas for the word problems and the horizontal segment of the intraparietal sulcus for the number problems. Copyright © 2011 Elsevier B.V. All rights reserved.

  7. Clean Air Act Requirements and History

    EPA Pesticide Factsheets

    In 1970 congress designed the Clean Air Act to combat a variety of air pollution problems, and to tackle emerging pollution threats such as public health, national welfare, toxic air pollutants, acid rain, protection of the ozone layer, and regional haze.

  8. Addressing the identification problem in age-period-cohort analysis: a tutorial on the use of partial least squares and principal components analysis.

    PubMed

    Tu, Yu-Kang; Krämer, Nicole; Lee, Wen-Chung

    2012-07-01

    In the analysis of trends in health outcomes, an ongoing issue is how to separate and estimate the effects of age, period, and cohort. As these 3 variables are perfectly collinear by definition, regression coefficients in a general linear model are not unique. In this tutorial, we review why identification is a problem, and how this problem may be tackled using partial least squares and principal components regression analyses. Both methods produce regression coefficients that fulfill the same collinearity constraint as the variables age, period, and cohort. We show that, because the constraint imposed by partial least squares and principal components regression is inherent in the mathematical relation among the 3 variables, this leads to more interpretable results. We use one dataset from a Taiwanese health-screening program to illustrate how to use partial least squares regression to analyze the trends in body heights with 3 continuous variables for age, period, and cohort. We then use another dataset of hepatocellular carcinoma mortality rates for Taiwanese men to illustrate how to use partial least squares regression to analyze tables with aggregated data. We use the second dataset to show the relation between the intrinsic estimator, a recently proposed method for the age-period-cohort analysis, and partial least squares regression. We also show that the inclusion of all indicator variables provides a more consistent approach. R code for our analyses is provided in the eAppendix.

  9. Adolescent Temperament: Childhood Problem Precursors and Problem Behavior Correlates.

    ERIC Educational Resources Information Center

    Windle, Michael

    Interrelations between childhood behavior problems and adolescent temperament, and between adolescent temperament and problem behaviors, were studied. A sample of 311 adolescents with an average age of 15.7 years completed self-report measures regarding behavior problems before age 13, temperament, alcohol consumption, alcohol-related problems,…

  10. Towards practical multiscale approach for analysis of reinforced concrete structures

    NASA Astrophysics Data System (ADS)

    Moyeda, Arturo; Fish, Jacob

    2017-12-01

    We present a novel multiscale approach for analysis of reinforced concrete structural elements that overcomes two major hurdles in utilization of multiscale technologies in practice: (1) coupling between material and structural scales due to consideration of large representative volume elements (RVE), and (2) computational complexity of solving complex nonlinear multiscale problems. The former is accomplished using a variant of computational continua framework that accounts for sizeable reinforced concrete RVEs by adjusting the location of quadrature points. The latter is accomplished by means of reduced order homogenization customized for structural elements. The proposed multiscale approach has been verified against direct numerical simulations and validated against experimental results.

  11. Bullying in schools: what is the problem, and how can educators solve it?

    PubMed

    Strohmeier, Dagmar; Noam, Gil G

    2012-01-01

    This chapter reviews recent research on bullying from an educator's perspective. It is well known that bullying, a serious issue in schools, can be prevented when educators intervene. But research has shown that it is difficult for educators to detect bullying situations in their school and intervene competently and effectively. This chapter examines how educators can detect bullying, how they can best tackle serious cases of bullying, and how they can best prevent bullying in the long run. Copyright © 2012 Wiley Periodicals, Inc., A Wiley Company.

  12. Eleven quick tips for running an interdisciplinary short course for new graduate students.

    PubMed

    Saunders, Timothy E; He, Cynthia Y; Koehl, Patrice; Ong, L L Sharon; So, Peter T C

    2018-03-01

    Quantitative reasoning and techniques are increasingly ubiquitous across the life sciences. However, new graduate researchers with a biology background are often not equipped with the skills that are required to utilize such techniques correctly and efficiently. In parallel, there are increasing numbers of engineers, mathematicians, and physical scientists interested in studying problems in biology with only basic knowledge of this field. Students from such varied backgrounds can struggle to engage proactively together to tackle problems in biology. There is therefore a need to establish bridges between those disciplines. It is our proposal that the beginning of graduate school is the appropriate time to initiate those bridges through an interdisciplinary short course. We have instigated an intensive 10-day course that brought together new graduate students in the life sciences from across departments within the National University of Singapore. The course aimed at introducing biological problems as well as some of the quantitative approaches commonly used when tackling those problems. We have run the course for three years with over 100 students attending. Building on this experience, we share 11 quick tips on how to run such an effective, interdisciplinary short course for new graduate students in the biosciences.

  13. A modelling tool for policy analysis to support the design of efficient and effective policy responses for complex public health problems.

    PubMed

    Atkinson, Jo-An; Page, Andrew; Wells, Robert; Milat, Andrew; Wilson, Andrew

    2015-03-03

    In the design of public health policy, a broader understanding of risk factors for disease across the life course, and an increasing awareness of the social determinants of health, has led to the development of more comprehensive, cross-sectoral strategies to tackle complex problems. However, comprehensive strategies may not represent the most efficient or effective approach to reducing disease burden at the population level. Rather, they may act to spread finite resources less intensively over a greater number of programs and initiatives, diluting the potential impact of the investment. While analytic tools are available that use research evidence to help identify and prioritise disease risk factors for public health action, they are inadequate to support more targeted and effective policy responses for complex public health problems. This paper discusses the limitations of analytic tools that are commonly used to support evidence-informed policy decisions for complex problems. It proposes an alternative policy analysis tool which can integrate diverse evidence sources and provide a platform for virtual testing of policy alternatives in order to design solutions that are efficient, effective, and equitable. The case of suicide prevention in Australia is presented to demonstrate the limitations of current tools to adequately inform prevention policy and discusses the utility of the new policy analysis tool. In contrast to popular belief, a systems approach takes a step beyond comprehensive thinking and seeks to identify where best to target public health action and resources for optimal impact. It is concerned primarily with what can be reasonably left out of strategies for prevention and can be used to explore where disinvestment may occur without adversely affecting population health (or equity). Simulation modelling used for policy analysis offers promise in being able to better operationalise research evidence to support decision making for complex problems

  14. Sizeable acquired subglottic cyst in a baby with Williams-Beuren syndrome: association or coincidence?

    PubMed

    Christoforidis, Athanasios; Tsakalides, Christos; Chatziavramidis, Angelos; Karagianni, Paraskevi; Dimitriadou, Meropi; Konstantinidis, Iordanis

    2013-10-15

    We describe a case of an acquired subglottic cyst presented with persistent stridor and voice hoarsening in a baby diagnosed with Williams-Beuren syndrome that was born premature and required intubation during neonatal period. We also comment on whether this is a coincidence or there can be an association between impaired elastogenesis, a feature of patients with the syndrome and the formation of a subglottic cyst. © 2013 Elsevier B.V. All rights reserved.

  15. Between myth and reality: genetically modified maize, an example of a sizeable scientific controversy.

    PubMed

    Wisniewski, Jean-Pierre; Frangne, Nathalie; Massonneau, Agnès; Dumas, Christian

    2002-11-01

    Maize is a major crop plant with essential agronomical interests and a model plant for genetic studies. With the development of plant genetic engineering technology, many transgenic strains of this monocotyledonous plant have been produced over the past decade. In particular, field-cultivated insect-resistant Bt-maize hybrids are at the centre of an intense debate between scientists and organizations recalcitrant to genetically modified organisms (GMOs). This debate, which addresses both safety and ethical aspects, has raised questions about the impact of genetically modified (GM) crops on the biodiversity of traditional landraces and on the environment. Here, we review some of the key points of maize genetic history as well as the methods used to stably transform this cereal. We describe the genetically engineered Bt-maizes available for field cultivation and we investigate the controversial reports on their impacts on non-target insects such as the monarch butterfly and on the flow of transgenes into Mexican maize landraces.

  16. Children with behavioral problems and motor problems have a worse neurological condition than children with behavioral problems only.

    PubMed

    Peters, Lieke H J; Maathuis, Carel G B; Hadders-Algra, Mijna

    2014-12-01

    Some evidence suggests that children with specific behavioral problems are at risk for motor problems. It is unclear whether neurological condition plays a role in the propensity of children with behavioral problems to develop motor problems. To examine the relation between behavioral problems, motor performance and neurological condition in school-aged children. Cross-sectional study. 174 children (95 boys) receiving mainstream education and 106 children (82 boys) receiving special education aged 6 to 13 years (mean 9 y 7 m, SD 1 y 10 m). Behavior was assessed with questionnaires: the parental Child Behavior Checklist (CBCL) and Teacher's Report Form (TRF). Motor performance was assessed with the Movement Assessment Battery for Children (MABC). MABC-scores ≥5th percentile were considered as age-adequate and scores <5th percentile indicated definite motor problems. Neurological condition was assessed in terms of Minor Neurological Dysfunction (MND). The majority of specific behavioral problems were associated with definite motor problems, except somatic complaints and rule breaking behavior. Children with externalizing problems, according to the CBCL or TRF, and motor problems had more often MND than children with externalizing problems only. The same holds true for internalizing problems according to the CBCL. The present study demonstrated that various forms of behavioral problems were associated with motor problems. Especially children with motor and behavioral problems showed MND. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Tackling Obesity in Children through Physical Activity: A Perspective from the United Kingdom

    ERIC Educational Resources Information Center

    Fox, Kenneth R.

    2004-01-01

    Childhood obesity has become an emotive and serious problem in Europe. In the UK, it has generated a great deal of interest by the media, health professionals, food companies, scientists, and more recently, the government. Upward trends have been recorded in most countries, levels are interestingly variable, and the origins of this variation have…

  18. Toward Solving the Problem of Problem Solving: An Analysis Framework

    ERIC Educational Resources Information Center

    Roesler, Rebecca A.

    2016-01-01

    Teaching is replete with problem solving. Problem solving as a skill, however, is seldom addressed directly within music teacher education curricula, and research in music education has not examined problem solving systematically. A framework detailing problem-solving component skills would provide a needed foundation. I observed problem solving…

  19. Problem Solvers: Problem--How Long Can You Stand?

    ERIC Educational Resources Information Center

    Teaching Children Mathematics, 2010

    2010-01-01

    Healthy lifestyles are increasingly emphasized these days. This month the authors begin a series of mathematical problems that also address physical activity. They hope that these problems offer opportunities to investigate mathematics and also reinforce the desire to lead a healthy life. In their first problem of the academic year, students…

  20. Measuring Family Problem Solving: The Family Problem Solving Diary.

    ERIC Educational Resources Information Center

    Kieren, Dianne K.

    The development and use of the family problem-solving diary are described. The diary is one of several indicators and measures of family problem-solving behavior. It provides a record of each person's perception of day-to-day family problems (what the problem concerns, what happened, who got involved, what those involved did, how the problem…

  1. Tackling the Anglophones' Free Ride: Fair Linguistic Cooperation with a Global Lingua Franca

    ERIC Educational Resources Information Center

    Van Parijs, Philippe

    2007-01-01

    In science and in all other domains that require communication across borders, we need one lingua franca, and this lingua franca will be English. The adoption of the native language of some as everyone's lingua franca unavoidably raises a problem of justice in various senses. One of these is cooperative justice, the fair distribution of the cost…

  2. Comfortable with Chaos: Operational Design in the Naval Special Warfare Planning Process

    DTIC Science & Technology

    2011-05-08

    President Alvaro Uribe Velez took office, Colombia was enduring a multi- faceted and interactively complex strategic situation. Three major insurgent groups...President Uribe took office and designed a comprehensive strategy to tackle the "wicked" problem. President Uribe designed an operational approach that...government -unattainable by previous presidents. From 2002 to 2006, the Uribe administration reframed 19 their understanding of the problem and

  3. Innovative park-and-ride management for livable communities.

    DOT National Transportation Integrated Search

    2015-08-31

    Park-and-ride (P&R) has been recognized as an effective way to tackle the challenge of the last-mile problem in public transportation, i.e., connecting transit stations to final destinations. Although the design and operations of P&R facilities have ...

  4. Innovative park-and-ride management for livable communities : final report.

    DOT National Transportation Integrated Search

    2015-08-31

    Park-and-ride (P&R) has been recognized as an effective way to tackle the challenge of the : last-mile problem in public transportation, i.e., connecting transit stations to final destinations. : Although the design and operations of P&R facilities h...

  5. SLIM: A Big Turn for Ion Separation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, Dick; Ibrahim, Yehia

    Researchers at PNNL have drastically increased the speed and separation of ions by tackling one problem: turning ions around a corner. Their technology, Structures for Lossless Ion Manipulations, or SLIM, could take the form of new instruments for doctors and other applications.

  6. Measuring the Value of AI in Space Science and Exploration

    NASA Astrophysics Data System (ADS)

    Blair, B.; Parr, J.; Diamond, B.; Pittman, B.; Rasky, D.

    2017-10-01

    FDL is tackling knowledge gaps useful to the space program by forming small teams of industrial partners, cutting-edge AI researchers and space science domain experts, and tasking them to solve problems that are important to NASA as well as humanity's future.

  7. How Many Disciplines Does It Take to Tackle Climate Change?

    NASA Astrophysics Data System (ADS)

    Campbell, S.; Calderazzo, J.

    2015-12-01

    Through my involvement in two multidisciplinary climate change education and outreach projects, the website 100 Views of Climate Change and Changing Climates @ Colorado State, I have come to understand that just as this problem is everybody's business, almost everybody has something to contribute to understanding and dealing with it. This is certainly true of the academic disciplines represented on college campuses, where faculty from nearly every department have relevant things to teach their students: speakers in a climate-change lecture series we organized came from 27 departments in 8 colleges, plus numerous other campus and local entities, and more could have been included. As one convener of this AGU session, I have worked to include a good sample of these varied and complementary disciplinary perspectives. Inevitably, though, this sample leaves significant gaps in what would constitute a robust cross-campus climate literacy, and I will talk about some of these missing disciplinary perspectives and why they are important.

  8. Peer deviance, parenting and disruptive behavior among young girls.

    PubMed

    Miller, Shari; Loeber, Rolf; Hipwell, Alison

    2009-02-01

    This study examined concurrent and longitudinal associations between peer deviance, parenting practices, and conduct and oppositional problems among young girls ages 7 and 8. Participants were 588 African American and European American girls who were part of a population-based study of the development of conduct problems and delinquency among girls. Affiliations with problem-prone peers were apparent among a sizeable minority of the girls, and these associations included both males and females. Although peer delinquency concurrently predicted disruptive behaviors, the gender of these peers did not contribute to girls' behavior problems. Harsh parenting and low parental warmth showed both concurrent and prospective associations with girls' disruptive behaviors. Similar patterns of association were seen for African American and European American girls. The findings show that peer and parent risk processes are important contributors to the early development of young girls' conduct and oppositional behaviors. These data contribute to our understanding of girls' aggression and antisocial behaviors and further inform our understanding of risk processes for these behaviors among young girls in particular.

  9. Peer Deviance, Parenting and Disruptive Behavior among Young Girls

    PubMed Central

    Miller, Shari; Loeber, Rolf; Hipwell, Alison

    2009-01-01

    This study examined concurrent and longitudinal associations between peer deviance, parenting practices, and conduct and oppositional problems among young girls ages 7 and 8. Participants were 588 African American and European American girls who were part of a population-based study of the development of conduct problems and delinquency among girls. Affiliations with problem-prone peers were apparent among a sizeable minority of the girls, and these associations included both males and females. Although peer delinquency concurrently predicted disruptive behaviors, the gender of these peers did not contribute to girls’ behavior problems. Harsh parenting and low parental warmth showed both concurrent and prospective associations with girls’ disruptive behaviors. Similar patterns of association were seen for African American and European American girls. The findings show that peer and parent risk processes are important contributors to the early development of young girls’ conduct and oppositional behaviors. These data contribute to our understanding of girls’ aggression and antisocial behaviors and further inform our understanding of risk processes for these behaviors among young girls in particular. PMID:18777132

  10. Problem Solving through an Optimization Problem in Geometry

    ERIC Educational Resources Information Center

    Poon, Kin Keung; Wong, Hang-Chi

    2011-01-01

    This article adapts the problem-solving model developed by Polya to investigate and give an innovative approach to discuss and solve an optimization problem in geometry: the Regiomontanus Problem and its application to football. Various mathematical tools, such as calculus, inequality and the properties of circles, are used to explore and reflect…

  11. Elimination Problems

    MedlinePlus

    ... Long-term Abdominal Pain (Stomach Pain), Short-term Ankle Problems Breast Problems in Men Breast Problems in Women Chest Pain in Infants and Children Chest Pain, Acute Chest Pain, Chronic Cold and Flu Cough Diarrhea ...

  12. Tooth Problems

    MedlinePlus

    ... Long-term Abdominal Pain (Stomach Pain), Short-term Ankle Problems Breast Problems in Men Breast Problems in Women Chest Pain in Infants and Children Chest Pain, Acute Chest Pain, Chronic Cold and Flu Cough Diarrhea ...

  13. Mouth Problems

    MedlinePlus

    ... Long-term Abdominal Pain (Stomach Pain), Short-term Ankle Problems Breast Problems in Men Breast Problems in Women Chest Pain in Infants and Children Chest Pain, Acute Chest Pain, Chronic Cold and Flu Cough Diarrhea ...

  14. Hip Problems

    MedlinePlus

    ... Long-term Abdominal Pain (Stomach Pain), Short-term Ankle Problems Breast Problems in Men Breast Problems in Women Chest Pain in Infants and Children Chest Pain, Acute Chest Pain, Chronic Cold and Flu Cough Diarrhea ...

  15. Ankle Problems

    MedlinePlus

    ... Long-term Abdominal Pain (Stomach Pain), Short-term Ankle Problems Breast Problems in Men Breast Problems in Women Chest Pain in Infants and Children Chest Pain, Acute Chest Pain, Chronic Cold and Flu Cough Diarrhea ...

  16. Knee Problems

    MedlinePlus

    ... Long-term Abdominal Pain (Stomach Pain), Short-term Ankle Problems Breast Problems in Men Breast Problems in Women Chest Pain in Infants and Children Chest Pain, Acute Chest Pain, Chronic Cold and Flu Cough Diarrhea ...

  17. Leg Problems

    MedlinePlus

    ... Long-term Abdominal Pain (Stomach Pain), Short-term Ankle Problems Breast Problems in Men Breast Problems in Women Chest Pain in Infants and Children Chest Pain, Acute Chest Pain, Chronic Cold and Flu Cough Diarrhea ...

  18. The Potential Improvement of Team-Working Skills in Biomedical and Natural Science Students Using a Problem-Based Learning Approach

    ERIC Educational Resources Information Center

    Nowrouzian, Forough L.; Farewell, Anne

    2013-01-01

    Teamwork has become an integral part of most organisations today, and it is clearly important in Science and other disciplines. In Science, research teams increase in size while the number of single-authored papers and patents decline. Team-work in laboratory sciences permits projects that are too big or complex for one individual to be tackled.…

  19. Problem? "No Problem!" Solving Technical Contradictions

    ERIC Educational Resources Information Center

    Kutz, K. Scott; Stefan, Victor

    2007-01-01

    TRIZ (pronounced TREES), the Russian acronym for the theory of inventive problem solving, enables a person to focus his attention on finding genuine, potential solutions in contrast to searching for ideas that "may" work through a happenstance way. It is a patent database-backed methodology that helps to reduce time spent on the problem,…

  20. Tackling cancer control in the Gulf Cooperation Council Countries.

    PubMed

    Al-Othman, Saleh; Haoudi, Abdelali; Alhomoud, Samar; Alkhenizan, Abdullah; Khoja, Tawfik; Al-Zahrani, Ali

    2015-05-01

    Cancer is a major health problem in both high income and middle-to-low income countries, and is the second leading cause of death in the world. Although more than a third of cancer could be prevented and another third could be cured if diagnosed early, it remains a huge challenge to health-care systems worldwide. Despite substantial improvements in health services some of the countries in the Gulf region, the burden of non-communicable diseases is a major threat, primarily due to the rapid socioeconomic shifts that have led to unfavourable changes in lifestyle such as increased tobacco use, decreased physical activity, and consumption of unhealthy food. In the Gulf Cooperation Council states (United Arab Emirates, Bahrain, Saudi Arabia, Oman, Qatar, and Kuwait), advanced breast cancer, colorectal cancer, leukaemia, thyroid cancer, and non-Hodgkin lymphomas are the most common cancers affecting younger populations compared with other countries. By contrast with cancer prevalence in developed countries, prostate, lung, and cervical cancers are not among the most common cancers in the Gulf region. In view of the increased cost of cancer management worldwide, integrated approaches between primary, secondary, and tertiary health-care systems with special focus on prevention and early detection is an essential step in the countries' efforts in the fight against cancer. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Problem solving stages in the five square problem

    PubMed Central

    Fedor, Anna; Szathmáry, Eörs; Öllinger, Michael

    2015-01-01

    According to the restructuring hypothesis, insight problem solving typically progresses through consecutive stages of search, impasse, insight, and search again for someone, who solves the task. The order of these stages was determined through self-reports of problem solvers and has never been verified behaviorally. We asked whether individual analysis of problem solving attempts of participants revealed the same order of problem solving stages as defined by the theory and whether their subjective feelings corresponded to the problem solving stages they were in. Our participants tried to solve the Five-Square problem in an online task, while we recorded the time and trajectory of their stick movements. After the task they were asked about their feelings related to insight and some of them also had the possibility of reporting impasse while working on the task. We found that the majority of participants did not follow the classic four-stage model of insight, but had more complex sequences of problem solving stages, with search and impasse recurring several times. This means that the classic four-stage model is not sufficient to describe variability on the individual level. We revised the classic model and we provide a new model that can generate all sequences found. Solvers reported insight more often than non-solvers and non-solvers reported impasse more often than solvers, as expected; but participants did not report impasse more often during behaviorally defined impasse stages than during other stages. This shows that impasse reports might be unreliable indicators of impasse. Our study highlights the importance of individual analysis of problem solving behavior to verify insight theory. PMID:26300794

  2. Problem solving stages in the five square problem.

    PubMed

    Fedor, Anna; Szathmáry, Eörs; Öllinger, Michael

    2015-01-01

    According to the restructuring hypothesis, insight problem solving typically progresses through consecutive stages of search, impasse, insight, and search again for someone, who solves the task. The order of these stages was determined through self-reports of problem solvers and has never been verified behaviorally. We asked whether individual analysis of problem solving attempts of participants revealed the same order of problem solving stages as defined by the theory and whether their subjective feelings corresponded to the problem solving stages they were in. Our participants tried to solve the Five-Square problem in an online task, while we recorded the time and trajectory of their stick movements. After the task they were asked about their feelings related to insight and some of them also had the possibility of reporting impasse while working on the task. We found that the majority of participants did not follow the classic four-stage model of insight, but had more complex sequences of problem solving stages, with search and impasse recurring several times. This means that the classic four-stage model is not sufficient to describe variability on the individual level. We revised the classic model and we provide a new model that can generate all sequences found. Solvers reported insight more often than non-solvers and non-solvers reported impasse more often than solvers, as expected; but participants did not report impasse more often during behaviorally defined impasse stages than during other stages. This shows that impasse reports might be unreliable indicators of impasse. Our study highlights the importance of individual analysis of problem solving behavior to verify insight theory.

  3. Methodological difficulties of conducting agroecological studies from a statistical perspective

    USDA-ARS?s Scientific Manuscript database

    Statistical methods for analysing agroecological data might not be able to help agroecologists to solve all of the current problems concerning crop and animal husbandry, but such methods could well help agroecologists to assess, tackle, and resolve several agroecological issues in a more reliable an...

  4. Pearson's Correlation between Three Variables; Using Students' Basic Knowledge of Geometry for an Exercise in Mathematical Statistics

    ERIC Educational Resources Information Center

    Vos, Pauline

    2009-01-01

    When studying correlations, how do the three bivariate correlation coefficients between three variables relate? After transforming Pearson's correlation coefficient r into a Euclidean distance, undergraduate students can tackle this problem using their secondary school knowledge of geometry (Pythagoras' theorem and similarity of triangles).…

  5. Worldwide Emerging Environmental Issues Affecting the U.S. Military. September 2005 Report

    DTIC Science & Technology

    2005-09-01

    Environment and global warming issues were mentioned in several speeches delivered by Heads of State and Governments at the UN Summit, however it was...not a dominant theme. There were calls to ratify international treaties designed to tackle environmental and global warming problems, and agreement

  6. "Let Your Data Tell a Story:" Climate Change Experts and Students Navigating Disciplinary Argumentation in the Classroom

    ERIC Educational Resources Information Center

    Walsh, Elizabeth Mary; McGowan, Veronica Cassone

    2017-01-01

    Science education trends promote student engagement in authentic knowledge in practice to tackle personally consequential problems. This study explored how partnering scientists and students on a social media platform supported students' development of disciplinary practice knowledge through practice-based learning with experts during two pilot…

  7. The Engaged University: International Perspectives on Civic Engagement. International Studies in Higher Education

    ERIC Educational Resources Information Center

    Watson, David; Hollister, Robert; Stroud, Susan E.; Babcock, Elizabeth

    2011-01-01

    "The Engaged University" is a comprehensive empirical account of the global civic engagement movement in higher education. In universities around the world, something extraordinary is underway. Mobilizing their human and intellectual resources, institutions of higher education are directly tackling community problems--combating poverty,…

  8. Learning the Digital Way: Evaluating Progress, Tackling Challenges. Technology Counts, 2015. Education Week. Volume 34, Number 35

    ERIC Educational Resources Information Center

    Edwards, Virginia B., Ed.

    2015-01-01

    Lofty ed-tech visions are always tempered by reality. Unexpected problems that arose during a launch of a 1-to-1 computing program and ambitious digital curriculum initiative in Los Angeles led to the dialing back of the effort. Financial, legal, and managerial repercussions continue to swirl in the wake. These problems should not prevent schools…

  9. A comprehensive classification method for VOC emission sources to tackle air pollution based on VOC species reactivity and emission amounts.

    PubMed

    Li, Guohao; Wei, Wei; Shao, Xia; Nie, Lei; Wang, Hailin; Yan, Xiao; Zhang, Rui

    2018-05-01

    In China, volatile organic compound (VOC) control directives have been continuously released and implemented for important sources and regions to tackle air pollution. The corresponding control requirements were based on VOC emission amounts (EA), but never considered the significant differentiation of VOC species in terms of atmospheric chemical reactivity. This will adversely influence the effect of VOC reduction on air quality improvement. Therefore, this study attempted to develop a comprehensive classification method for typical VOC sources in the Beijing-Tianjin-Hebei region (BTH), by combining the VOC emission amounts with the chemical reactivities of VOC species. Firstly, we obtained the VOC chemical profiles by measuring 5 key sources in the BTH region and referencing another 10 key sources, and estimated the ozone formation potential (OFP) per ton VOC emission for these sources by using the maximum incremental reactivity (MIR) index as the characteristic of source reactivity (SR). Then, we applied the data normalization method to respectively convert EA and SR to normalized EA (NEA) and normalized SR (NSR) for various sources in the BTH region. Finally, the control index (CI) was calculated, and these sources were further classified into four grades based on the normalized CI (NCI). The study results showed that in the BTH region, furniture coating, automobile coating, and road vehicles are characterized by high NCI and need to be given more attention; however, the petro-chemical industry, which was designated as an important control source by air quality managers, has a lower NCI. Copyright © 2017. Published by Elsevier B.V.

  10. Tackling optimization challenges in industrial load control and full-duplex radios

    NASA Astrophysics Data System (ADS)

    Gholian, Armen

    In price-based demand response programs in smart grid, utilities set the price in accordance with the grid operating conditions and consumers respond to price signals by conducting optimal load control to minimize their energy expenditure while satisfying their energy needs. Industrial sector consumes a large portion of world electricity and addressing optimal load control of energy-intensive industrial complexes, such as steel industry and oil-refinery, is of practical importance. Formulating a general industrial complex and addressing issues in optimal industrial load control in smart grid is the focus of the second part of this dissertation. Several industrial load details are considered in the proposed formulation, including those that do not appear in residential or commercial load control problems. Operation under different smart pricing scenarios, namely, day-ahead pricing, time-of-use pricing, peak pricing, inclining block rates, and critical peak pricing are considered. The use of behind-the-meter renewable generation and energy storage is also considered. The formulated optimization problem is originally nonlinear and nonconvex and thus hard to solve. However, it is then reformulated into a tractable linear mixed-integer program. The performance of the design is assessed through various simulations for an oil refinery and a steel mini-mill. In the third part of this dissertation, a novel all-analog RF interference canceler is proposed. Radio self-interference cancellation (SIC) is the fundamental enabler for full-duplex radios. While SIC methods based on baseband digital signal processing and/or beamforming are inadequate, an all-analog method is useful to drastically reduce the self-interference as the first stage of SIC. It is shown that a uniform architecture with uniformly distributed RF attenuators has a performance highly dependent on the carrier frequency. It is also shown that a new architecture with the attenuators distributed in a clustered

  11. Tackling gender inequalities and intimate partner violence in the response to HIV: moving towards effective interventions in Southern and Eastern Africa.

    PubMed

    Gibbs, Andrew

    2016-07-01

    Ending intimate partner violence (IPV) and reducing gender inequalities are recognised as critical to "'ending AIDS" by 2030. Amongst women, experiencing IPV has been shown to increase HIV acquisition, reduce women's ability to use HIV prevention strategies and reduce adherence to antiretroviral therapy (ART). In Southern and Eastern Africa there has recently been a significant push to strengthen programming around this through broad funding and programming streams. However, while gender inequality underpins IPV and HIV acquisition, in different contexts a variety of other factors intersect to shape this vulnerability. Using reflections focused on young women living in urban informal settlements and the Stepping Stones and Creating Futures intervention, this paper illustrates the need to understand the specific drivers of HIV and IPV in any given context and the need for interventions to prevent this. Any intervention needs to include three key components: 1) resonate with the lived realities of women they target; 2) tackle multiple factors shaping women's vulnerability to IPV and HIV simultaneously; and 3) consider how best to work with men and boys to achieve improved outcomes for women. Such an approach, it is argued, resonating with the "slow research" movement, will yield better outcomes for interventions, but will also require a fundamental rethinking of how interventions to prevent IPV and HIV amongst women are conceptualised, with a greater emphasis on understanding the ways in which gender resonates in each context and how interventions can operate.

  12. Thinking Process of Naive Problem Solvers to Solve Mathematical Problems

    ERIC Educational Resources Information Center

    Mairing, Jackson Pasini

    2017-01-01

    Solving problems is not only a goal of mathematical learning. Students acquire ways of thinking, habits of persistence and curiosity, and confidence in unfamiliar situations by learning to solve problems. In fact, there were students who had difficulty in solving problems. The students were naive problem solvers. This research aimed to describe…

  13. Problem-Oriented Learning in Geography Education: Construction of Motivating Problems

    ERIC Educational Resources Information Center

    Weiss, Günther

    2017-01-01

    This article reports on the possibilities and challenges of starting problem-oriented learning in geography lessons. The article focuses on the features of motivating problems, because one of the essential functions of the problem to start with is to animate learners to solve it. The analysis of various introductions to problem-oriented learning…

  14. Solving Problems.

    ERIC Educational Resources Information Center

    Hale, Norman; Lindelow, John

    Chapter 12 in a volume on school leadership, this chapter cites the work of several authorities concerning problem-solving or decision-making techniques based on the belief that group problem-solving effort is preferable to individual effort. The first technique, force-field analysis, is described as a means of dissecting complex problems into…

  15. Periodic reference tracking control approach for smart material actuators with complex hysteretic characteristics

    NASA Astrophysics Data System (ADS)

    Sun, Zhiyong; Hao, Lina; Song, Bo; Yang, Ruiguo; Cao, Ruimin; Cheng, Yu

    2016-10-01

    Micro/nano positioning technologies have been attractive for decades for their various applications in both industrial and scientific fields. The actuators employed in these technologies are typically smart material actuators, which possess inherent hysteresis that may cause systems behave unexpectedly. Periodic reference tracking capability is fundamental for apparatuses such as scanning probe microscope, which employs smart material actuators to generate periodic scanning motion. However, traditional controller such as PID method cannot guarantee accurate fast periodic scanning motion. To tackle this problem and to conduct practical implementation in digital devices, this paper proposes a novel control method named discrete extended unparallel Prandtl-Ishlinskii model based internal model (d-EUPI-IM) control approach. To tackle modeling uncertainties, the robust d-EUPI-IM control approach is investigated, and the associated sufficient stabilizing conditions are derived. The advantages of the proposed controller are: it is designed and represented in discrete form, thus practical for digital devices implementation; the extended unparallel Prandtl-Ishlinskii model can precisely represent forward/inverse complex hysteretic characteristics, thus can reduce modeling uncertainties and benefits controllers design; in addition, the internal model principle based control module can be utilized as a natural oscillator for tackling periodic references tracking problem. The proposed controller was verified through comparative experiments on a piezoelectric actuator platform, and convincing results have been achieved.

  16. Models, solution, methods and their applicability of dynamic location problems (DLPs) (a gap analysis for further research)

    NASA Astrophysics Data System (ADS)

    Seyedhosseini, Seyed Mohammad; Makui, Ahmad; Shahanaghi, Kamran; Torkestani, Sara Sadat

    2016-09-01

    Determining the best location to be profitable for the facility's lifetime is the important decision of public and private firms, so this is why discussion about dynamic location problems (DLPs) is a critical significance. This paper presented a comprehensive review from 1968 up to most recent on published researches about DLPs and classified them into two parts. First, mathematical models developed based on different characteristics: type of parameters (deterministic, probabilistic or stochastic), number and type of objective function, numbers of commodity and modes, relocation time, number of relocation and relocating facilities, time horizon, budget and capacity constraints and their applicability. In second part, It have been also presented solution algorithms, main specification, applications and some real-world case studies of DLPs. At the ends, we concluded that in the current literature of DLPs, distribution systems and production-distribution systems with simple assumption of the tackle to the complexity of these models studied more than any other fields, as well as the concept of variety of services (hierarchical network), reliability, sustainability, relief management, waiting time for services (queuing theory) and risk of facility disruption need for further investigation. All of the available categories based on different criteria, solution methods and applicability of them, gaps and analysis which have been done in this paper suggest the ways for future research.

  17. Individualized Math Problems in Percent. Oregon Vo-Tech Mathematics Problem Sets.

    ERIC Educational Resources Information Center

    Cosler, Norma, Ed.

    This is one of eighteen sets of individualized mathematics problems developed by the Oregon Vo-Tech Math Project. Each of these problem packages is organized around a mathematical topic and contains problems related to diverse vocations. Solutions are provided for all problems. This volume includes problems concerned with computing percents.…

  18. Individualized Math Problems in Fractions. Oregon Vo-Tech Mathematics Problem Sets.

    ERIC Educational Resources Information Center

    Cosler, Norma, Ed.

    This is one of eighteen sets of individualized mathematics problems developed by the Oregon Vo-Tech Math Project. Each of these problem packages is organized around a mathematical topic and contains problems related to diverse vocations. Solutions are provided for all problems. This package contains problems involving computation with common…

  19. Individualized Math Problems in Geometry. Oregon Vo-Tech Mathematics Problem Sets.

    ERIC Educational Resources Information Center

    Cosler, Norma, Ed.

    This is one of eighteen sets of individualized mathematics problems developed by the Oregon Vo-Tech Math Project. Each of these problem packages is organized around a mathematical topic and contains problems related to diverse vocations. Solutions are provided for all problems. The volume contains problems in applied geometry. Measurement of…

  20. Individualized Math Problems in Integers. Oregon Vo-Tech Mathematics Problem Sets.

    ERIC Educational Resources Information Center

    Cosler, Norma, Ed.

    This is one of eighteen sets of individualized mathematics problems developed by the Oregon Vo-Tech Math Project. Each of these problem packages is organized around a mathematical topic and contains problems related to diverse vocations. Solutions are provided for all problems. This volume presents problems involving operations with positive and…

  1. Individualized Math Problems in Algebra. Oregon Vo-Tech Mathematics Problem Sets.

    ERIC Educational Resources Information Center

    Cosler, Norma, Ed.

    This is one of eighteen sets of individualized mathematics problems developed by the Oregon Vo-Tech Math Project. Each of these problem packages is organized around a mathematical topic, and contains problems related to diverse vocations. Solutions are provided for all problems. Problems presented in this package concern ratios used in food…

  2. Individualized Math Problems in Trigonometry. Oregon Vo-Tech Mathematics Problem Sets.

    ERIC Educational Resources Information Center

    Cosler, Norma, Ed.

    This is one of eighteen sets of individualized mathematics problems developed by the Oregon Vo-Tech Math Project. Each of these problem packages is organized around a mathematical topic and contains problems related to diverse vocations. Solutions are provided for all problems. Problems in this volume require the use of trigonometric and inverse…

  3. Problem Solvers: Problem--Jesse's Train

    ERIC Educational Resources Information Center

    James, Julie; Steimle, Alice

    2014-01-01

    Persevering in problem solving and constructing and critiquing mathematical arguments are some of the mathematical practices included in the Common Core State Standards for Mathematics (CCSSI 2010). To solve unfamiliar problems, students must make sense of the situation and apply current knowledge. Teachers can present such opportunities by…

  4. Comparing clinical and demographic characteristics of people with mental illness in hospital- and community-based residential rehabilitation units in Queensland.

    PubMed

    Meehan, Tom; Stedman, Terry; Parker, Stephen; Curtis, Bretine; Jones, Donna

    2017-05-01

    Objective The aim of the present study was to examine care pathways and characteristics of mental health consumers participating in both hospital- and community-based residential rehabilitation programs. Methods An audit of consumers (n=240) in all publicly funded residential rehabilitation units in Queensland was performed on the same day in 2013. Data collection focused on demographic characteristics, clinical information and measures of consumer functioning. Results Significant differences emerged for consumers in community- and hospital-based services with regard to age, length of stay, functioning, Mental Health Act status, guardianship status, family contact and risk of violence. Consumers in hospital-based programs have more severe and complex problems. Conclusions Consumers in residential rehabilitation units have high levels of disability, poor physical health and high levels of vulnerability. Nonetheless, it is likely that a sizeable proportion of consumers occupying rehabilitation beds in Queensland could be discharged if more 'step-down' options to move patients on were available. What is known about the topic? A small subgroup of people with severe and complex mental health problems is likely to require time in a residential rehabilitation program. This group is characterised by failure to respond to treatment, severe negative symptoms and some degree of cognitive impairment. What does this paper add? Patients currently occupying residential rehabilitation beds in Queensland have high levels of disability, poor physical health and high levels of vulnerability. Patients in hospital-based programs are more severely disabled than those in community-based programs. What are the implications for practitioners? It is likely that a sizeable proportion of patients occupying rehabilitation beds in Queensland could be discharged if more 'step-down' options were available. Future planning initiatives need to focus on developing a greater array of community

  5. Adolescent Problem Behavior and Problem Driving in Young Adulthood

    ERIC Educational Resources Information Center

    Bingham, C. Raymond; Shope, Jean T.

    2004-01-01

    Motor vehicle crashes are the leading cause of death among drivers younger than age 35, making problem driving behavior among young drivers a significant public concern. Effective intervention requires a better understanding of the antecedents of problem driving. Problem behavior theory, social control theory, and Kandel's model of substance use…

  6. Individualized Math Problems in Decimals. Oregon Vo-Tech Mathematics Problem Sets.

    ERIC Educational Resources Information Center

    Cosler, Norma, Ed.

    THis is one of eighteen sets of individualized mathematics problems developed by the Oregon Vo-Tech Math Project. Each of these problem packages is organized around a mathematical topic and contains problems related to diverse vocations. Solutions are provided for all problems. Problems in this volume concern use of decimals and are related to the…

  7. Individualized Math Problems in Volume. Oregon Vo-Tech Mathematics Problem Sets.

    ERIC Educational Resources Information Center

    Cosler, Norma, Ed.

    This is one of eighteen sets of individualized mathematics problems developed by the Oregon Vo-Tech Math Project. Each of these problem packages is organized around a mathematical topic and contains problems related to diverse vocations. Solutions are provided for all problems. Problems in this booklet require the computation of volumes of solids,…

  8. Using Challenging Tasks for Formative Assessment on Quadratic Functions with Senior Secondary Students

    ERIC Educational Resources Information Center

    Wilkie, Karina J.

    2016-01-01

    Senior secondary mathematics students who develop conceptual understanding that moves them beyond "rules without reasons" to connections between related concepts are in a strong place to tackle the more difficult mathematics application problems. Current research is examining how the use of challenging tasks at different levels of…

  9. The Use of Instructional Design in Educational Technology for Effective Teaching and Learning

    ERIC Educational Resources Information Center

    Gillani, Syeda Nosheen; Gujjar, Aijaz Ahmed; Choudhry, Bushra Naoreen

    2008-01-01

    Educationists are of the opinion that the educational problems relating to quantity and quality could be tackled by the proper utilization of instructional technology. Instructional technology is a systematic way of designing, carrying out and evaluating the teaching learning process. Instructional technology makes instruction more effective,…

  10. Multivariate mixed linear model analysis of longitudinal data: an information-rich statistical technique for analyzing disease resistance data

    USDA-ARS?s Scientific Manuscript database

    The mixed linear model (MLM) is currently among the most advanced and flexible statistical modeling techniques and its use in tackling problems in plant pathology has begun surfacing in the literature. The longitudinal MLM is a multivariate extension that handles repeatedly measured data, such as r...

  11. Poverty, Disability, and Employment: Global Perspectives from the National Centre for Promotion of Employment for Disabled People

    ERIC Educational Resources Information Center

    Abidi, Javed; Sharma, Dorodi

    2014-01-01

    The worldwide problems of disability, poverty, and unemployment stem out of the interaction of multiple factors including social stigma, stereotypes, lack of access to physical infrastructure, information, and enabling environments. Given this, a singular approach toward tackling these interrelated issues falls short. This article attempts to…

  12. Evaluation and expression analysis of alfalfa genotypes in response to prolonged salt stress

    USDA-ARS?s Scientific Manuscript database

    Salinity is one of the most important abiotic stresses that adversely affect plant growth and productivity globally. In order to tackle this complex problem, it is important to link the biochemical and physiological responses with the underlying genetic mechanisms. In this study, we used 12 previous...

  13. Venous thromboembolism: a UK perspective.

    PubMed

    Kakkar, Ajay

    2009-07-01

    Venous thromboembolism remains a significant cause of morbidity and mortality in the UK, and its dangers, particularly in hospitalized patients, have long been recognized. Recent measures to tackle this problem and new treatments should alleviate the burden of venous thromboembolism for patients, their families and hospital services.

  14. Managers with Impact: Verstile and Inconsistent

    ERIC Educational Resources Information Center

    Skinner, Wickham; Sasser, W. Earl

    1977-01-01

    Based on analysis of 31 management case studies, the authors conclude that managers who are consistent in the way they tackle day-to-day problems are likely to be much less successful than managers who analyze each situation individually and adjust their approach accordingly. (Author/JG)

  15. Strategies of Rural Development in Asia--A Discussion. Summary of Discussion, Research Studies and Country Statements Presented to the Seminar on Approaches to Rural Development in Asia (Malaysia, May-June, 1975).

    ERIC Educational Resources Information Center

    Inayatullah, C., Ed.

    A 10-day seminar for senior government officials concerned with making rural development policies in selected Asian countries focused on programs adopted by various Asian governments to tackle rural development problems. To compare various approaches, seven indicators of rural development were used: agricultural productivity; rural employment;…

  16. Rapid and Reliable Single Nucleotide Polymorphism-Based Differentiation of Brucella Live Vaccine Strains from Field Strains

    USDA-ARS?s Scientific Manuscript database

    Brucellosis is a major zoonotic disease responsible for substantial social and economic problems, particularly in the developing world. One element that can implemented as part of control programs tackling animal disease is the use of one of the OIE recommended vaccines to protect against either Bru...

  17. Tackling the "so what" problem in scientific research: a systems-based approach to resource and publication tracking.

    PubMed

    Harris, Paul A; Kirby, Jacqueline; Swafford, Jonathan A; Edwards, Terri L; Zhang, Minhua; Yarbrough, Tonya R; Lane, Lynda D; Helmer, Tara; Bernard, Gordon R; Pulley, Jill M

    2015-08-01

    Peer-reviewed publications are one measure of scientific productivity. From a project, program, or institutional perspective, publication tracking provides the quantitative data necessary to guide the prudent stewardship of federal, foundation, and institutional investments by identifying the scientific return for the types of support provided. In this article, the authors describe the Vanderbilt Institute for Clinical and Translational Research's (VICTR's) development and implementation of a semiautomated process through which publications are automatically detected in PubMed and adjudicated using a "just-in-time" workflow by a known pool of researchers (from Vanderbilt University School of Medicine and Meharry Medical College) who receive support from Vanderbilt's Clinical and Translational Science Award. Since implementation, the authors have (1) seen a marked increase in the number of publications citing VICTR support, (2) captured at a more granular level the relationship between specific resources/services and scientific output, (3) increased awareness of VICTR's scientific portfolio, and (4) increased efficiency in complying with annual National Institutes of Health progress reports. They present the methodological framework and workflow, measures of impact for the first 30 months, and a set of practical lessons learned to inform others considering a systems-based approach for resource and publication tracking. They learned that contacting multiple authors from a single publication can increase the accuracy of the resource attribution process in the case of multidisciplinary scientific projects. They also found that combining positive (e.g., congratulatory e-mails) and negative (e.g., not allowing future resource requests until adjudication is complete) triggers can increase compliance with publication attribution requests.

  18. The factors affecting Nigeria's success toward implementation of global public health priorities.

    PubMed

    Echebiri, Vitalis C

    2015-06-01

    This paper examines the challenges facing the Nigerian government toward the implementation of global public health priories. The Nigerian government recognizes the need to implement these priorities by putting in place the necessary policy framework, but political instability, poor infrastructural development and inadequate funding have remained barriers toward the achievement of success in implementing these priorities. The rest of the paper elucidates the fact that despite leadership and influence from the World Health Organization and other United Nations agencies, and some responses from the Nigerian government, tackling these public health problems requires much more fundamental reform to primary health services and a reduction in poverty. Although the government has shown enough political will to tackle these problems, it is expected that a better result will be achieved through injecting more funds into the Nigerian health sector, and deploying astute health administrators to manage the sector rather than pure health professionals without managerial acumen. © The Author(s) 2014.

  19. Differences in the Processes of Solving Physics Problems between Good Physics Problem Solvers and Poor Physics Problem Solvers.

    ERIC Educational Resources Information Center

    Finegold, M.; Mass, R.

    1985-01-01

    Good problem solvers and poor problem solvers in advanced physics (N=8) were significantly different in their ability in translating, planning, and physical reasoning, as well as in problem solving time; no differences in reliance on algebraic solutions and checking problems were noted. Implications for physics teaching are discussed. (DH)

  20. Developing Metacognitive and Problem-Solving Skills through Problem Manipulation

    ERIC Educational Resources Information Center

    Parker Siburt, Claire J.; Bissell, Ahrash N.; Macphail, Richard A.

    2011-01-01

    In a collaborative effort between the our university's department of chemistry and the academic resource center, we designed a model for general chemistry recitation based on a problem manipulation method in which students actively assess the skills and knowledge used to answer a chemical problem and then manipulate the problem to create a new…

  1. The Association between Attention Problems and Internalizing and Externalizing Problems: The Mediating Role of Peer Problems

    ERIC Educational Resources Information Center

    Yip, Vania T.; Ang, Rebecca P.; Ooi, Yoon Phaik; Fung, Daniel S. S.; Mehrotra, Kala; Sung, Min; Lim, Choon Guan

    2013-01-01

    Background: The high prevalence of attention problems in children warrants concern, as it is a risk factor for internalizing and externalizing problems. There lies a need to understand possible factors that may mediate this link so that interventions may be targeted to alleviate these mediators and interrupt the link between attention problems and…

  2. Matrix Interdiction Problem

    NASA Astrophysics Data System (ADS)

    Kasiviswanathan, Shiva Prasad; Pan, Feng

    In the matrix interdiction problem, a real-valued matrix and an integer k is given. The objective is to remove a set of k matrix columns that minimizes in the residual matrix the sum of the row values, where the value of a row is defined to be the largest entry in that row. This combinatorial problem is closely related to bipartite network interdiction problem that can be applied to minimize the probability that an adversary can successfully smuggle weapons. After introducing the matrix interdiction problem, we study the computational complexity of this problem. We show that the matrix interdiction problem is NP-hard and that there exists a constant γ such that it is even NP-hard to approximate this problem within an n γ additive factor. We also present an algorithm for this problem that achieves an (n - k) multiplicative approximation ratio.

  3. Tackling the threat of antimicrobial resistance: from policy to sustainable action

    PubMed Central

    Shallcross, Laura J.; Howard, Simon J.; Fowler, Tom; Davies, Sally C.

    2015-01-01

    Antibiotics underpin all of modern medicine, from routine major surgery through to caesarean sections and modern cancer therapies. These drugs have revolutionized how we practice medicine, but we are in a constant evolutionary battle to evade microbial resistance and this has become a major global public health problem. We have overused and misused these essential medicines both in the human and animal health sectors and this threatens the effectiveness of antimicrobials for future generations. We can only address the threat of antimicrobial resistance (AMR) through international collaboration across human and animal health sectors integrating social, economic and behavioural factors. Our global organizations are rising to the challenge with the recent World Health Assembly resolution on AMR and development of the Global Action plan but we must act now to avoid a return to a pre-antibiotic era. PMID:25918440

  4. Global Health Education and Advocacy: Using BMJ Case Reports to Tackle the Social Determinants of Health.

    PubMed

    Douthit, Nathan T; Biswas, Seema

    2018-01-01

    Since 2013, BMJ Case Reports (http://casereports.bmj.com/) has published over 70 global health case reports from five continents, written by doctors, nurses, students, and allied health professionals. These cases, a burgeoning repository of evidence of how real patients are affected by disease, trauma, violence, sexual assault, conflict, migration, adverse living and working conditions, and poor access to health care, discuss, in addition to clinicopathological findings, the global health problems affecting each patient. The global health problem analysis examines the problems of individual patients, critically appraises the literature, and describes actual and potential solutions for the patient, the local community, and patients affected by similar issues across the world. At present global health literature and learning materials lack a patient focus and real-life context in the analysis of global health problems. BMJ Case Reports global health case reports are a unique and important tool to learn about and advocate for change in the social, political, cultural, and financial determinants of health as they affect real patients. This growing evidence base brings together clinicians, local service providers, policy makers, and government and non-governmental institutions to effect real change in patients' lives toward improving health. Each global health case report is an excellent resource for learning, and together, these case reports provide essential reading for anyone embarking on a career in global health, and writing their own case report. The online course (http://casereports.bmj.com/site/misc/GHMA_Mar_2017.pptx) at BMJ Case Reports uses these cases and is free to access.

  5. Problem Management Module: An Innovative System to Improve Problem List Workflow

    PubMed Central

    Hodge, Chad M.; Kuttler, Kathryn G.; Bowes, Watson A.; Narus, Scott P.

    2014-01-01

    Electronic problem lists are essential to modern health record systems, with a primary goal to serve as the repository of a patient’s current health issues. Additionally, coded problems can be used to drive downstream activities such as decision support, evidence-based medicine, billing, and cohort generation for research. Meaningful Use also requires use of a coded problem list. Over the course of three years, Intermountain Healthcare developed a problem management module (PMM) that provided innovative functionality to improve clinical workflow and boost problem list adoption, e.g. smart search, user customizable views, problem evolution, and problem timelines. In 23 months of clinical use, clinicians entered over 70,000 health issues, the percentage of free-text items dropped to 1.2%, completeness of problem list items increased by 14%, and more collaborative habits were initiated. PMID:25954372

  6. Update in the treatment of schizophrenia.

    PubMed

    Katz, I; Kac, M

    1993-04-01

    The large number of drugs available to treat schizophrenia and the emergence of atypical and newer agents that provide efficiency with lessening of side effects may not only serve to provide more amelioration against this disease, but may also help us to unravel the neurochemical defects of the disorder. Despite these encouraging trends, the reality is that schizophrenia is still a devastating illness for a sizeable minority affected with the condition, that a 'cure' is not yet possible, and that drug therapies alone will not provide all that is required in acute or continuing management. Supporting care in the community for patient and family are just as important as pharmacotherapy in managing this problem.

  7. The A3 Problem Solving Report: A 10-Step Scientific Method to Execute Performance Improvements in an Academic Research Vivarium

    PubMed Central

    Bassuk, James A.; Washington, Ida M.

    2013-01-01

    The purpose of this study was to illustrate the application of A3 Problem Solving Reports of the Toyota Production System to our research vivarium through the methodology of Continuous Performance Improvement, a lean approach to healthcare management at Seattle Children's (Hospital, Research Institute, Foundation). The Report format is described within the perspective of a 10-step scientific method designed to realize measurable improvements of Issues identified by the Report's Author, Sponsor and Coach. The 10-step method (Issue, Background, Current Condition, Goal, Root Cause, Target Condition, Countermeasures, Implementation Plan, Test, and Follow-up) was shown to align with Shewhart's Plan-Do-Check-Act process improvement cycle in a manner that allowed for quantitative analysis of the Countermeasure's outcomes and of Testing results. During fiscal year 2012, 9 A3 Problem Solving Reports were completed in the vivarium under the teaching and coaching system implemented by the Research Institute. Two of the 9 reports are described herein. Report #1 addressed the issue of the vivarium's veterinarian not being able to provide input into sick animal cases during the work day, while report #7 tackled the lack of a standard in keeping track of weekend/holiday animal health inspections. In each Report, a measurable Goal that established the basis for improvement recognition was present. A Five Whys analysis identified the Root Cause for Report #1 as historical work patterns that existed before the veterinarian was hired on and that modern electronic communication tools had not been implemented. The same analysis identified the Root Cause for Report #7 as the vivarium had never standardized the process for weekend/holiday checks. Successful outcomes for both Reports were obtained and validated by robust audit plans. The collective data indicate that vivarium staff acquired a disciplined way of reporting on, as well as solving, problems in a manner consistent with high

  8. Reciprocating Risks of Peer Problems and Aggression for Children's Internalizing Problems

    ERIC Educational Resources Information Center

    Hoglund, Wendy L. G.; Chisholm, Courtney A.

    2014-01-01

    Three complementary models of how peer relationship problems (exclusion and victimization) and aggressive behaviors relate to prospective levels of internalizing problems are examined. The additive risks model proposes that peer problems and aggression cumulatively increase risks for internalizing problems. The reciprocal risks model hypothesizes…

  9. Using an isomorphic problem pair to learn introductory physics: Transferring from a two-step problem to a three-step problem

    NASA Astrophysics Data System (ADS)

    Lin, Shih-Yin; Singh, Chandralekha

    2013-12-01

    In this study, we examine introductory physics students’ ability to perform analogical reasoning between two isomorphic problems which employ the same underlying physics principles but have different surface features. 382 students from a calculus-based and an algebra-based introductory physics course were administered a quiz in the recitation in which they had to learn from a solved problem provided and take advantage of what they learned from it to solve another isomorphic problem (which we call the quiz problem). The solved problem provided has two subproblems while the quiz problem has three subproblems, which is known from previous research to be challenging for introductory students. In addition to the solved problem, students also received extra scaffolding supports that were intended to help them discern and exploit the underlying similarities of the isomorphic solved and quiz problems. The data analysis suggests that students had great difficulty in transferring what they learned from a two-step problem to a three-step problem. Although most students were able to learn from the solved problem to some extent with the scaffolding provided and invoke the relevant principles in the quiz problem, they were not necessarily able to apply the principles correctly. We also conducted think-aloud interviews with six introductory students in order to understand in depth the difficulties they had and explore strategies to provide better scaffolding. The interviews suggest that students often superficially mapped the principles employed in the solved problem to the quiz problem without necessarily understanding the governing conditions underlying each principle and examining the applicability of the principle in the new situation in an in-depth manner. Findings suggest that more scaffolding is needed to help students in transferring from a two-step problem to a three-step problem and applying the physics principles appropriately. We outline a few possible strategies

  10. "What constitutes a 'problem'?" Producing 'alcohol problems' through online counselling encounters.

    PubMed

    Savic, Michael; Ferguson, Nyssa; Manning, Victoria; Bathish, Ramez; Lubman, Dan I

    2017-08-01

    Typically, health policy, practice and research views alcohol and other drug (AOD) 'problems' as objective things waiting to be detected, diagnosed and treated. However, this approach to policy development and treatment downplays the role of clinical practices, tools, discourses, and systems in shaping how AOD use is constituted as a 'problem'. For instance, people might present to AOD treatment with multiple psycho-social concerns, but usually only a singular AOD-associated 'problem' is considered serviceable. As the assumed nature of 'the serviceable problem' influences what treatment responses people receive, and how they may come to be enacted as 'addicted' or 'normal' subjects, it is important to subject clinical practices of problem formulation to critical analysis. Given that the reach of AOD treatment has expanded via the online medium, in this article we examine how 'problems' are produced in online alcohol counselling encounters involving people aged 55 and over. Drawing on poststructural approaches to problematisation, we not only trace how and what 'problems' are produced, but also what effects these give rise to. We discuss three approaches to problem formulation: (1) Addiction discourses at work; (2) Moving between concerns and alcohol 'problems'; (3) Making 'problems' complex and multiple. On the basis of this analysis, we argue that online AOD counselling does not just respond to pre-existing 'AOD problems'. Rather, through the social and clinical practices of formulation at work in clinical encounters, online counselling also produces them. Thus, given a different set of circumstances, practices and relations, 'problems' might be defined or emerge differently-perhaps not as 'problems' at all or perhaps as different kinds of concerns. We conclude by highlighting the need for a critical reflexivity in AOD treatment and policy in order to open up possibilities for different ways of engaging with, and responding to, people's needs in their complexity

  11. How do open-ended problems promote mathematical creativity? A reflection of bare mathematics problem and contextual problem

    NASA Astrophysics Data System (ADS)

    Wijaya, A.

    2018-03-01

    Creativity is often seen as one of the fundamental aspects of character education. As one of the 21st century skills, creativity has also been considered as an important goal of education across the world. This paper reports a study on promoting mathematical creativity through the use of open-ended mathematics problems. A total of 53 undergraduate students participated in the study. These students worked on open-ended problems in two types, i.e. bare mathematics problem and contextual problem. The contextual problem was presented in the form of paper-based and Geogebra-based. The students’ works were analysed qualitatively in order to describe how students’ mathematical creativity developed. It was found that the open-ended problems successfully promote students’ creativity as indicated by various solutions or strategies that were used by students to solve the problems. The analysis of students’ works show that students’ creativity developed through three kinds of exploration, i. e. (1) exploration of contexts, (2) exploration of software features, and (3) exploration of mathematics concepts. The use of metacognitive questioning was found to be helpful to develop the first two explorations into mathematical exploration.

  12. Parents Who Abuse: What Are They Thinking?

    ERIC Educational Resources Information Center

    Seng, Alexandra C.; Prinz, Ronald J.

    2008-01-01

    Child abuse is a major social concern around the world. Important to tackling the problem is an understanding of the mechanisms contributing to abusive parenting. This article brings together research on the cognitive variables associated with abusive or high-risk parenting. Considered are dysfunctional child-centered and parent-centered…

  13. Media Detectives: Bridging the Relationship among Empathy, Laugh Tracks, and Gender in Childhood

    ERIC Educational Resources Information Center

    Kanthan, Sruti; Graham, James A.; Azarchi, Lynne

    2016-01-01

    Empathy in college-age students is decreasing at unprecedented rates. Understanding empathy in children can act as primary prevention in tackling the problem. This study considers laugh tracks' capacity to bias reality, foster empathy, and investigate differences across time and gender in 181 fifth grade students. Findings from this…

  14. Teaching Analytical Chemistry to Pharmacy Students: A Combined, Iterative Approach

    ERIC Educational Resources Information Center

    Masania, Jinit; Grootveld, Martin; Wilson, Philippe B.

    2018-01-01

    Analytical chemistry has often been a difficult subject to teach in a classroom or lecture-based context. Numerous strategies for overcoming the inherently practical-based difficulties have been suggested, each with differing pedagogical theories. Here, we present a combined approach to tackling the problem of teaching analytical chemistry, with…

  15. Making Sense of School Turnarounds

    ERIC Educational Resources Information Center

    Hess, Frederick M.

    2012-01-01

    Today, in a sector flooded with $3.5 billion in School Improvement Grant funds and the resulting improvement plans, there's great faith that "turnaround" strategies are a promising way to tackle stubborn problems with persistently low-performing schools. Unlike traditional reform efforts, with their emphasis on incremental improvement, turnarounds…

  16. Improving Collaborative Learning in Online Software Engineering Education

    ERIC Educational Resources Information Center

    Neill, Colin J.; DeFranco, Joanna F.; Sangwan, Raghvinder S.

    2017-01-01

    Team projects are commonplace in software engineering education. They address a key educational objective, provide students critical experience relevant to their future careers, allow instructors to set problems of greater scale and complexity than could be tackled individually, and are a vehicle for socially constructed learning. While all…

  17. Marketing Education's National Marketing Plan.

    ERIC Educational Resources Information Center

    Zwissler, Karen

    1987-01-01

    Discusses formation of the National Council for Marketing Education and how its Marketing Strategy Committee developed a plan to tackle the image problem. The committee chose five target audiences and developed a strategy to reach each target. The plan was introduced in October 1987 through a national videoconference. (CH)

  18. Scaffolding Students' Skill Development by First Introducing Advanced Techniques through the Synthesis and [superscript 15]N NMR Analysis of Cinnamamides

    ERIC Educational Resources Information Center

    Shuldburg, Sara; Carroll, Jennifer

    2017-01-01

    An advanced undergraduate experiment involving the synthesis and characterization of a series of six unique cinnamamides is described. This experiment allows for a progressive mastery of skills students need to tackle more complex NMR structure elucidation problems. Characterization of the products involves IR spectroscopy, GCMS, and proton,…

  19. A Guide to Implementing Response to Intervention in Long-Term Residential Juvenile Justice Schools

    ERIC Educational Resources Information Center

    McDaniel, Sara; Heil, Kristen M.; Houchins, David E.; Duchaine, Ellen L.

    2011-01-01

    Since the passage of the Individuals with Disabilities Education Improvement Act (2004), public schools have been permitted to use a response to intervention model to address academic and social problems of students and identify students with disabilities. As the collective educational community tackles implementation of response to intervention…

  20. Knowledge Creation and Human Capital for Development: The Role of Graduate Entrepreneurship

    ERIC Educational Resources Information Center

    Mitra, Jay; Abubakar, Y. A.; Sagagi, M.

    2011-01-01

    Purpose: Tackling structural and emergent problems in the labour market, valorising skilled human capital (HC) for opportunity creation, economic development and growth, are some of the key drivers for graduate entrepreneurship. This paper aims to examine developments in Africa, focusing on the significance of improving human capital through…

  1. Infusing Ethics into the Development of Engineers: Exemplary Education Activities and Programs

    ERIC Educational Resources Information Center

    National Academies Press, 2016

    2016-01-01

    Ethical practice in engineering is critical for ensuring public trust in the field and in its practitioners, especially as engineers increasingly tackle international and socially complex problems that combine technical and ethical challenges. This report aims to raise awareness of the variety of exceptional programs and strategies for improving…

  2. Educating Our Black Children: New Directions and Radical Approaches.

    ERIC Educational Resources Information Center

    Majors, Richard, Ed.

    This collection of papers from U.S. and British contributors focuses on positive social inclusion policy and practice for black students. There are 15 chapters in five parts. Part 1, "Tackling Historical and Contemporary Education Problems," includes: (1) "Racism, Policy and the (Mis)Education of Black Children" (David…

  3. Demographic, Employment and Development Trends: The Need for Integrated Planning.

    ERIC Educational Resources Information Center

    Farooq, Ghazi M.; MacKellar, F. Landis

    1990-01-01

    The authors contend that problems associated with rapid population growth in developing countries must be tackled through comprehensive planning. They discuss impacts of demography on labor supply and demand and migration. Then they propose a practical framework for population and human resource development planning and policy formation. (SK)

  4. Data Use and Inquiry in Research-Practice Partnerships: Four Case Examples

    ERIC Educational Resources Information Center

    Biag, Manuelito; Gerstein, Amy; Fehrer, Kendra; Sanchez, Monika; Sipes, Laurel

    2016-01-01

    The four case examples presented in this brief are drawn from the Gardner Center's substantial experience conducting rigorous research in research-practice partnerships. The first case describes a partnership approach that enhances a school district's capacity to use integrated longitudinal data to tackle persistent problems of practice and…

  5. How to Motivate Adults with Low Literacy and Numeracy Skills to Engage and Persist in Learning: A Literature Review of Policy Interventions

    ERIC Educational Resources Information Center

    Windisch, Hendrickje Catriona

    2016-01-01

    Low basic skills levels of adults are a complex policy problem which has neither straightforward causes nor solutions, and successful interventions are still relatively rare. Tackling serious literacy and numeracy weaknesses among adults is challenging, partly because the task itself is difficult, and partly because even if accomplished…

  6. Using Facebook to deliver a social norm intervention to reduce problem drinking at university.

    PubMed

    Ridout, Brad; Campbell, Andrew

    2014-11-01

    University students usually overestimate peer alcohol use, resulting in them 'drinking up' to perceived norms. Social norms theory suggests correcting these inflated perceptions can reduce alcohol consumption. Recent findings by the current authors show portraying oneself as 'a drinker' is considered by many students to be a socially desirable component of their Facebook identity, perpetuating an online culture that normalises binge drinking. However, social networking sites have yet to be utilised in social norms interventions. Actual and perceived descriptive and injunctive drinking norms were collected from 244 university students. Ninety-five students screened positive for hazardous drinking and were randomly allocated to a control group or intervention group that received social norms feedback via personalised Facebook private messages over three sessions. At 1 month post-intervention, the quantity and frequency of alcohol consumed by intervention group during the previous month had significantly reduced compared with baseline and controls. Reductions were maintained 3 months post-intervention. Intervention group perceived drinking norms were significantly more accurate post-intervention. This is the first study to test the feasibility of using Facebook to deliver social norms interventions. Correcting misperceptions of peer drinking norms resulted in clinically significant reductions in alcohol use. Facebook has many advantages over traditional social norms delivery, providing an innovative method for tackling problem drinking at university. These results have implications for the use of Facebook to deliver positive messages about safe alcohol use to students, which may counter the negative messages regarding alcohol normally seen on Facebook. © 2014 Australasian Professional Society on Alcohol and other Drugs.

  7. Student-Posed Problems

    NASA Astrophysics Data System (ADS)

    Harper, Kathleen A.; Etkina, Eugenia

    2002-10-01

    As part of weekly reports,1 structured journals in which students answer three standard questions each week, they respond to the prompt, If I were the instructor, what questions would I ask or problems assign to determine if my students understood the material? An initial analysis of the results shows that some student-generated problems indicate fundamental misunderstandings of basic physical concepts. A further investigation explores the relevance of the problems to the week's material, whether the problems are solvable, and the type of problems (conceptual or calculation-based) written. Also, possible links between various characteristics of the problems and conceptual achievement are being explored. The results of this study spark many more questions for further work. A summary of current findings will be presented, along with its relationship to previous work concerning problem posing.2 1Etkina, E. Weekly Reports;A Two-Way Feedback Tool, Science Education, 84, 594-605 (2000). 2Mestre, J.P., Probing Adults Conceptual Understanding and Transfer of Learning Via Problem Posing, Journal of Applied Developmental Psychology, 23, 9-50 (2002).

  8. The Human Communication Research Centre dialogue database.

    PubMed

    Anderson, A H; Garrod, S C; Clark, A; Boyle, E; Mullin, J

    1992-10-01

    The HCRC dialogue database consists of over 700 transcribed and coded dialogues from pairs of speakers aged from seven to fourteen. The speakers are recorded while tackling co-operative problem-solving tasks and the same pairs of speakers are recorded over two years tackling 10 different versions of our two tasks. In addition there are over 200 dialogues recorded between pairs of undergraduate speakers engaged on versions of the same tasks. Access to the database, and to its accompanying custom-built search software, is available electronically over the JANET system by contacting liz@psy.glasgow.ac.uk, from whom further information about the database and a user's guide to the database can be obtained.

  9. Ada Dual-Use Summary: Ada Dual-Use Workshop Held in Vienna, Virginia on October 19-20, 1993. Ada Dual-Use Committee Briefing, November 8, 1993

    DTIC Science & Technology

    1993-11-29

    Certification: Initial Continuing Fund Experimentatlonal Research: Same Design , Implement In Ada, C, C++ Same Problem, Develop With Multiple Methodologies ...allowing analysts ( non programmers) to ’parit’ specifications for screens, reports, databases and etc 2) generating from design specifications 75% of...before the non -defense sector did and designed a tool to tackle the problem. DOD tested the tool and it worked. But DOD hasn’t put Ada to work in a

  10. Question Generation for Learning by Reading

    DTIC Science & Technology

    2005-01-01

    Socratic Method has been recognized as a way of guiding students to understanding by prompting them to explore a domain through the use of thorough...questioning. We believe that the Socratic tutor is also role- modeling the appropriate questions to ask when tackling a problem or exploring a new...them when related problem or novel domains present themselves. Because of this, we are wiring the Socratic Method into the heart of the Ruminator’s

  11. Development and Demonstration of Autonomous Behaviors for Urban Environment Exploration

    DTIC Science & Technology

    2012-04-01

    exploration, mapping, localization, autonomy, lidar , SLAM 1. INTRODUCTION As global conflicts move into more urban settings, unmanned ground vehicles...mounted Hokuyo lidar is paired with a vertically mounted Hokuyo lidar as an inexpensive way for 3D perception of the environment. In addition, a pair...and mapping ( SLAM ) problem do exist,2–4 most have yet to tackle the problem of online SLAM throughout a multi-story building and/or incorporating

  12. Twilight Zones and Cornerstones. A Gnat Robot Double Feature

    DTIC Science & Technology

    1989-07-01

    be the best avenues to pursue. In the first section, we relate some background on recent work in micromotors and propose a new type of actua- tor, a...piezoelectric micromotor , which looks promising for effectively coupling mechanical power out to a load. The second section addresses the problem of...1. Micromotors The first problem we need to tackle in making gnat robots realistic is developing an actuator that can deliver some useful power to a

  13. Diagnosing plant problems

    Treesearch

    Cheryl A. Smith

    2008-01-01

    Diagnosing Christmas tree problems can be a challenge, requiring a basic knowledge of plant culture and physiology, the effect of environmental influences on plant health, and the ability to identify the possible causes of plant problems. Developing a solution or remedy to the problem depends on a proper diagnosis, a process that requires recognition of a problem and...

  14. Social Problem Solving, Conduct Problems, and Callous-Unemotional Traits in Children

    ERIC Educational Resources Information Center

    Waschbusch, Daniel A.; Walsh, Trudi M.; Andrade, Brendan F.; King, Sara; Carrey, Normand J.

    2007-01-01

    This study examined the association between social problem solving, conduct problems (CP), and callous-unemotional (CU) traits in elementary age children. Participants were 53 children (40 boys and 13 girls) aged 7-12 years. Social problem solving was evaluated using the Social Problem Solving Test-Revised, which requires children to produce…

  15. Seventh Grade Students' Problem Solving Success Rates on Proportional Reasoning Problems

    ERIC Educational Resources Information Center

    Pelen, Mustafa Serkan; Artut, Perihan Dinç

    2016-01-01

    This research was conducted to investigate 7th grade students' problem solving success rates on proportional reasoning problems and whether these success rates change with different problem types. 331 randomly selected students of grade seven participated in this study. A problem test which contains three different types of missing value (direct…

  16. General Tricomi-Rassias problem and oblique derivative problem for generalized Chaplygin equations

    NASA Astrophysics Data System (ADS)

    Wen, Guochun; Chen, Dechang; Cheng, Xiuzhen

    2007-09-01

    Many authors have discussed the Tricomi problem for some second order equations of mixed type, which has important applications in gas dynamics. In particular, Bers proposed the Tricomi problem for Chaplygin equations in multiply connected domains [L. Bers, Mathematical Aspects of Subsonic and Transonic Gas Dynamics, Wiley, New York, 1958]. And Rassias proposed the exterior Tricomi problem for mixed equations in a doubly connected domain and proved the uniqueness of solutions for the problem [J.M. Rassias, Lecture Notes on Mixed Type Partial Differential Equations, World Scientific, Singapore, 1990]. In the present paper, we discuss the general Tricomi-Rassias problem for generalized Chaplygin equations. This is one general oblique derivative problem that includes the exterior Tricomi problem as a special case. We first give the representation of solutions of the general Tricomi-Rassias problem, and then prove the uniqueness and existence of solutions for the problem by a new method. In this paper, we shall also discuss another general oblique derivative problem for generalized Chaplygin equations.

  17. A Finite-Volume approach for compressible single- and two-phase flows in flexible pipelines with fluid-structure interaction

    NASA Astrophysics Data System (ADS)

    Daude, F.; Galon, P.

    2018-06-01

    A Finite-Volume scheme for the numerical computations of compressible single- and two-phase flows in flexible pipelines is proposed based on an approximate Godunov-type approach. The spatial discretization is here obtained using the HLLC scheme. In addition, the numerical treatment of abrupt changes in area and network including several pipelines connected at junctions is also considered. The proposed approach is based on the integral form of the governing equations making it possible to tackle general equations of state. A coupled approach for the resolution of fluid-structure interaction of compressible fluid flowing in flexible pipes is considered. The structural problem is solved using Euler-Bernoulli beam finite elements. The present Finite-Volume method is applied to ideal gas and two-phase steam-water based on the Homogeneous Equilibrium Model (HEM) in conjunction with a tabulated equation of state in order to demonstrate its ability to tackle general equations of state. The extensive application of the scheme for both shock tube and other transient flow problems demonstrates its capability to resolve such problems accurately and robustly. Finally, the proposed 1-D fluid-structure interaction model appears to be computationally efficient.

  18. Teaching Problem Solving without Modeling through "Thinking Aloud Pair Problem Solving."

    ERIC Educational Resources Information Center

    Pestel, Beverly C.

    1993-01-01

    Reviews research relevant to the problem of unsatisfactory student problem-solving abilities and suggests a teaching strategy that addresses the issue. Author explains how she uses teaching aloud problem solving (TAPS) in college chemistry and presents evaluation data. Among the findings are that the TAPS class got fewer problems completely right,…

  19. Kolkata Restaurant Problem as a Generalised El Farol Bar Problem

    NASA Astrophysics Data System (ADS)

    Chakrabarti, Bikas K.

    Generalisation of the El Farol bar problem to that of many bars here leads to the Kolkata restaurant problem, where the decision to go to any restaurant or not is much simpler (depending on the previous experience of course, as in the El Farol bar problem). This generalised problem can be exactly analysed in some limiting cases discussed here. The fluctuation in the restaurant service can be shown to have precisely an inverse cubic behavior, as widely seen in the stock market fluctuations.

  20. Walking Problems

    MedlinePlus

    ... as Parkinson's disease Diseases such as arthritis or multiple sclerosis Vision or balance problems Treatment of walking problems depends on the cause. Physical therapy, surgery, or mobility aids may help.