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1

Tradition and Individuality in Wang Anshi's Tang bai jia shixuan  

Microsoft Academic Search

Xiaoshan Yang examines the controversy concerning why Wang Anshi (1021-1086) should have omitted many canonical poets, such as Li Bai, Du Fu, and Han Yu, when compiling his anthology, Tang bai jia shixuan-the largest anthology of Tang poetry up to its time. Yang argues that Wang's anthology is not as idiosyncratic as many commentators contended but is instead derivative of

Xiaoshan Yang

2010-01-01

2

Tradition and Individuality in Wang Anshi's Tang bai jia shixuan  

Microsoft Academic Search

:Xiaoshan Yang examines the controversy concerning why Wang Anshi (1021-1086) should have omitted many canonical poets, such as Li Bai, Du Fu, and Han Yu, when compiling his anthology, Tang bai jia shixuan-the largest anthology of Tang poetry up to its time. Yang argues that Wang's anthology is not as idiosyncratic as many commentators contended but is instead derivative of

Xiaoshan Yang

2010-01-01

3

The insulin sensitizing effect of homoisoflavone-enriched fraction in Liriope platyphylla Wang et Tang via PI3-kinase pathway.  

PubMed

In the present study, we screened candidates for enhancing insulin action, using glucose uptake as an indicator, from Liriope platyphylla Wang et Tang (LPWT) extract, Liliaceae, in 3T3-L1 adipocytes. The mechanism of insulin sensitizing action in the fractions was also investigated. LPWT extract with 70% MeOH was sequentially separated with Diaion HP-20 and silica gel column chromatography. The 9:1 fraction from silica gel column chromatography increased glucose uptake with 1 ng/mL up to glucose uptake with 50 ng/mL insulin. The 9:1 fraction, determined as homoisoflavone-enriched fraction, worked as an insulin sensitizer. It increased insulin stimulated glucose uptake in 3T3-L1 adipocytes, insulin responsive cells, through increased glucose transporter 4 (GLUT4) contents in the plasma membrane. GLUT4 translocation was increased through insulin receptor substrate 1 (IRS1)-PI3 kinase-Akt signaling mechanism. Thus, homoisoflavone-enriched fraction in LPWT extract played an important role as an insulin sensitizer in adipocytes. PMID:15369701

Choi, Soo Bong; Wha, Jun Dong; Park, Sunmin

2004-10-15

4

Comet Ge-Wang  

NASA Astrophysics Data System (ADS)

Comet Ge-Wang (1988o) was discovered by GE Yong-liang and WANG Qi at Xinglong Station of Beijing Observatory on November 4, 1988. Thirteen observations of this comet were collected in China and abroad and calculated its orbit. It passed the perihelion on May 23, 1988. Ephemerides up to April 1991 are given.

Ge, Yong-Liang; Wang, Qi; Han, Tao

1989-03-01

5

77 FR 34339 - Yufeng Wei, a/k/a Annie Wei, 165 Beech Street, Belmont, MA 02378; Order Denying Export Privileges  

Federal Register 2010, 2011, 2012, 2013

...COMMERCE Bureau of Industry and Security Yufeng Wei, a/k/a Annie Wei, 165 Beech...District Court, District of Massachusetts, Yufeng Wei, a/k/a Annie Wei (``Wei...ordered I. Until January 28, 2021, Yufeng Wei, a/k/a Annie Wei, with a...

2012-06-11

6

Space Wei QI: The Launch of Shenzhou V.  

National Technical Information Service (NTIS)

Wei Qi is the favorite Chinese board game chess with more than two hundred pieces rather than sixteen, allowing for significantly increased strategic complexity. When Lieutenant Colonel Yang Liwei lifted off into space from China's Jiuquan launch site jus...

J. Johnson-Freese

2004-01-01

7

Communicating between the Apple and the Wang  

SciTech Connect

This manual covers what the beginner needs to know in order to transfer files between an Apple's Microcomputer and a Wang's OIS Word Processor. We have also tried to indicate where the experienced user might want to look for additional details. We cover the use of Apple Writer )(, VisiTerm, VisiCalc, and EasyWriter Professional. For us, the two most useful connections are from Applewriter to Wang and from Visicalc to Wang. From Wang to Apple Writer via Visiterm may have some value. Files can be transferred by VisiTerm to Wang, but they arrive with RETURNS in the middle of words, which have to be edited out, so we do not recommend it. We describe how to go from EasyWriter to Wang, but we do not know how to go from Wang to EasyWriter. We see no reason to go from Wang to VisiCalc, so we haven't thought about it. All instructions are given for a typical configuration of the Apple, namely the one on which this manual was composed. It is detailed in the section on Hardware and Software.

Barton, G.W., Downey, R.

1982-10-26

8

T'ang Dynasty Tomb Figure.  

ERIC Educational Resources Information Center

Uses a print of a T'ang Dynasty tomb figure to acquaint grades 10-12 students with the tools needed for developing aesthetic judgement and artistic criticism. Includes background on the artwork and instructional strategies to help students describe the object, analyze the artmaking process, and formulate their own opinions. (GEA)

Selle, Penny

1988-01-01

9

Evaluation of Moon-tang on allergic reactions.  

PubMed

Moon-tang (M-tang) is a traditional Korean medicine that has been used for the treatment of various allergic disorders. However, the precise antiallergic effect and mechanism of it remain unknown. To figure out accurately the effect of M-tang on mast cell-mediated allergic reactions, we measured parameters including changes in the compound 48/80-induced systemic anaphylaxis, ear-swelling response, histamine release, passive cutaneous anaphylaxis (PCA), and tumor necrosis factor (TNF)-? secretion and expression, which related to allergic inflammatory reaction. The oral administration of M-tang inhibited systemic anaphylaxis and ear-swelling response in mice. M-tang suppressed the PCA and histamine release. In addition, M-tang and its active component, ?-eudesmol, inhibited the TNF-? production and expression in activated mast cells. These results suggest that M-tang may be a beneficial applicability as a candidate for an antiallergic agent. PMID:20946015

Kim, Na-Hyung; Kang, In-Cheol; Kim, Hyung-Min; Jeong, Hyun-Ja

2010-10-14

10

Lung cancer and indoor air pollution in Xuan Wei, China  

SciTech Connect

In Xuan Wei County, Yunnan Province, lung cancer mortality is among China's highest and, especially in females, is more closely associated with indoor burning of smoky coal, as opposed to wood or smokeless coal, than with tobacco smoking. Indoor air samples were collected during the burning of all three fuels. In contrast to wood and smokeless coal emissions, smoky coal emission has high concentrations of submicron particles containing mutagenic organics, especially in aromatic and polar fractions. These studies suggested an etiologic link between domestic smoky coal burning and lung cancer in Xuan Wei.

Mumford, J.L.; He, X.Z.; Chapman, R.S.; Cao, S.R.; Harris, D.B.; Li, X.M.; Xian, Y.L.; Jiang, W.Z.; Xu, C.W.; Chuang, J.C.

1987-01-09

11

Safety Evaluation of Yukmijihwang-tang: Assessment of Acute and Subchronic Toxicity in Rats  

PubMed Central

Yukmijihwang-tang (YMJ; Liu wei di huang tang (China), Rokumigan (Japan)) has been used in the treatment of diseases including renal disorder, cognitive vitality, and diabetes mellitus. However, there is very little information regarding the toxicity of YMJ to give an assurance of safety for clinical treatment. To provide safety information for YMJ, we evaluated its acute and sub-chronic toxicity in rats. The single-dose toxicity of YMJ was examined using Sprague-Dawley rats. Rats were treated with YMJ extract orally at 0, 500, 1000, or 2000?mg/kg body weight. After a single administration, clinical signs were observed every day for two weeks, and body weights were measured five times, including an initial measurement on day 1 (the day of administration). In the sub-chronic oral toxicity study, YMJ was administered to rats at 0, 500, 1000, or 2000?mg/kg/day for 13 weeks. Mortalities, clinical signs, body weight changes, food and water consumption, ophthalmologic findings, urinalysis, hematological and biochemical parameters, gross findings, organ weights, and histological examination were monitored during the study period. We found no mortality and no abnormalities in clinical signs, body weights, and necropsy findings for any of the animals in the acute and sub-chronic studies following oral administration in the rat at up to 2000?mg/kg/day YMJ. YMJ may not have any single-dose toxicity; the LD50 of YMJ was over 2000?mg/kg, and it is safe for rats. The no-observed-adverse-effect-level (NOAEL) was considered to be 2000?mg/kg/day.

Ha, Hyekyung; Lee, Jun Kyoung; Lee, Ho Young; Koh, Woo Suk; Seo, Chang Seob; Lee, Mi-Young; Huang, Dae Sun; Shin, Hyeunkyoo

2011-01-01

12

[Textual Research on Wang Fengchun's Life].  

PubMed

WANG Fengchun (1884 - 1949), born in Wu County, Jiangsu Province, was one of the four famous doctors of Beijing in the Republic of China periods. He learned Confucianism during his childhood and then learned medicine from AI Buchan, a famous doctor in Wuzhong area. In 1908, he went to Beijing and was appointed as the prosecutor of the court of law and a medical official, but also had learnt medicine from LI Jun, the head of the Business Ministry. In 1910, Wang resigned and lived as doctor in Beijing. According to the literature, from 1935 to 1942, Wang had been appointed 11 times as a member of Beiping (Beijing) TCM examination committee or test committee. In 1938, he was appointed as president of the Beijing Branch of the National Medical Professional Association and created the Beijing Medicine Monthly in 1939. In September 1939, Wang began to make preparations for a TCM symposium, i.e. the Medicine Symposium which was established officially in October 1939. In 1941, he was appointed as the director of the Beijing Traditional Chinese Medicines Workshop, employing famous doctors to cultivate reserve talents of medicines. Being a realist, he often exchanged opinions with TCM and western medical doctors and also made a contribution to medical education. PMID:22613482

Wang, Ti

2012-01-01

13

Immobilization of glyoxylic acid on Wang resin  

Microsoft Academic Search

We report herein the simple preparation of immobilized glyoxylic acid, where the acid function is either linked through an amide or an ester bond to Wang resin. These compounds represent interesting aldehyde inputs for the generation of new libraries of small molecules.

Nathalie Schlienger; Martin R Bryce; Thomas K Hansen

2000-01-01

14

Wu-wei and the question of the other  

Microsoft Academic Search

In the dissertation I have presented a historical, comparative, and systematic study on the issue of the relation between aesthetic subjects and ethical subjects by focusing on the philosophers Lao-zi, Zhuang-zi, Mencius, Tu Wei-ming, Heidegger, Derrida, Foucault, and Levinas. By “aesthetic” I mean “amoral” in the Kierkegaardian sense, and by “ethical” I mean care and compassion for others in the

Changchi Hao

2002-01-01

15

Wang-Landau or Statistical Mechanics  

NASA Astrophysics Data System (ADS)

The Wang-Landau algorithm and its variations provide a method for estimating a self-consistent density of states -- or equivalently the entropy -- of a system with many degrees of freedom. Possible benefits from generating a self-consistent estimate of the entropy and its derivative are presented for models with both discrete and continuous values of the energy. In addition, the advantage of computing thermodynamic quantities as derivatives of the estimated entropy over summation over the density of states is shown.

Brown, Gregory; Nicholson, Donald M.; Eisenbach, Markus; Odbadrakh, Kh.

2013-03-01

16

Stochasticity of comet P\\/Ge-Wang  

Microsoft Academic Search

Three comets are now known to be at or near the 1\\/1 resonance with Jupiter: P\\/Slaughter-Burnham, P\\/Boethin and P\\/Ge-Wang. Although details of the individual orbits differ, the three comets have very similar general dynamic behavior: their orbits show many transitions between the different types of resonant motion (satellite libration, anti-satellite libration and circulating motion). The stochastic character of such cometary

D. Benest; R. Gonczi

1994-01-01

17

Wang linker free of side reactions.  

PubMed

A new resin for the solid-phase synthesis of peptide acids was developed. It was based on a linker with two unique features: methoxy groups as the only activating groups of the phenyl ring and a copper(I)-catalyzed Click chemistry reaction to anchor it to the solid support. The efficiency of this new resin in solid phase peptide synthesis was compared with that of Wang resin. PMID:23270537

Castro, Vida; Rodriguez, Hortensia; Albericio, Fernando

2012-12-27

18

Compressing random microstructures via stochastic Wang tilings  

NASA Astrophysics Data System (ADS)

This Rapid Communication presents a stochastic Wang tiling-based technique to compress or reconstruct disordered microstructures on the basis of given spatial statistics. Unlike the existing approaches based on a single unit cell, it utilizes a finite set of tiles assembled by a stochastic tiling algorithm, thereby allowing to accurately reproduce long-range orientation orders in a computationally efficient manner. Although the basic features of the method are demonstrated for a two-dimensional particulate suspension, the present framework is fully extensible to generic multidimensional media.

Novák, Jan; Ku?erová, Anna; Zeman, Jan

2012-10-01

19

ASSESSING INDOOR AIR POLLUTION EXPOSURE AND LUNG CANCER RISK IN XUAN WEI, CHINA  

EPA Science Inventory

This report presents risk assessment-related aspects of a multidisciplinary study of indoor coal smoke po1lution and lung cancer in Xuan Wei County, Yunnan Province, China. uan Wei presents a unique natural experiment in environmental carcinogenesis because lung cancer mortality ...

20

EPIDEMIOLOGY OF LUNG CANCER IN XUAN WEI, CHINA: CURRENT PROGRESS, ISSUES, AND RESEARCH STRATEGIES (JOURNAL VERSION)  

EPA Science Inventory

In Xuan Wei, a rural Chinese county of about one million people, females' annual lung cancer mortality is China's highest, and males' is among China's highest. Xuan Wei's very high indoor air pollution levels (sometimes exceeding 20 mg/m3), residentially stable population, relati...

21

Pharmacological evaluation of LiuWei Zhuanggu Granules in rats.  

PubMed

Many commonly consumed foods, herbs and spices contain a complex array of naturally occurring bioactive molecules called phytochemicals, which may confer health benefits. In this study, the impact of LiuWei Zhuanggu Granules (LWZGG) on mineral metabolism in osteopenia development was evaluated. Results showed that serum estrogen, bone gla protein (BGP), and calcitonin (CT) levels, bone Ca, Zn and Cu levels, femur, lumbar vertebrae and trabecular bone density, tibia maximum stress and maximum bending strength were increased, and serum parathyroid hormone (PTH), serum and urine Ca, Zn and Cu levels were decreased in rat bone. It can be concluded that LWZGG is useful to improve bone quality in ovariectomized (OVX) rats. PMID:22759913

Zhu, Haiming; Ding, Liang; Xiao, Haijun; Ni, Weifeng; Xue, Feng; He, Zhiming

2012-07-03

22

Flapping wings: viscous effects in Lighthill--Weis-Fogh mechanism  

NASA Astrophysics Data System (ADS)

The Lighthill--Weis-Fogh ``clap-fling-sweep'' description of insect flight involves a novel mechanism, which can apparently operate in a strictly inviscid fluid, of generation of circulation and lift through instantaneous change of topology. However, viscous effects substantially influence this mechanism, both near the sharp edges of the wings by the well-known vortex-shedding process, and in the neighbourhood of the ``hinge,'' where the local Reynolds number is necessarily low. In this investigation, we focus on viscous effects at and around the instant of separation of the wings. The local flow near the hinge is described by similarity solutions of the Stokes (biharmonic) equation, and a logarithmic singularity of the pressure is identified. Numerical simulation of the process provides support for the analytical description.

Kolomenskiy, Dmitry; Moffatt, H. Keith; Farge, Marie; Schneider, Kai

2008-11-01

23

Massively parallel Wang Landau sampling on multiple GPUs  

SciTech Connect

Wang Landau sampling is implemented on the Graphics Processing Unit (GPU) with the Compute Unified Device Architecture (CUDA). Performances on three different GPU cards, including the new generation Fermi architecture card, are compared with that on a Central Processing Unit (CPU). The parameters for massively parallel Wang Landau sampling are tuned in order to achieve fast convergence. For simulations of the water cluster systems, we obtain an average of over 50 times speedup for a given workload.

Yin, Junqi [ORNL; Landau, D. P. [UGA

2012-01-01

24

[Facts of medical works written by Wang Ji].  

PubMed

There is a lot of medical works written by the noted physician of Ming dynasty, Wang Ji. However, exactly how many works were written by him, remains obscure. By investigation, it is known that altogether he wrote 11 kinds of books in 70 volumes, among them, 2 kinds in 4 volumes were copied manuscripts. On the basis of this, the dates and editions of these manuscripts were made clear. This is of significance to the study of Wang's life story. PMID:11624247

Wang, X; Zhang, L

1999-10-01

25

Action of Sosiho-Tang on systemic and local anaphylaxis by anal administration.  

PubMed

The herbal formulation Soshiho-Tang (SS-Tang) has been used against allergic disease for generations, and still occupies an important place in traditional medicine in Korea. Previously, we reported that SS-Tang potently inhibited mast cell- mediated anaphylaxis when orally administered. In this study, we investigated the effect of SS-Tang by anal administration in anaphylaxis responses. SS-Tang dose-dependently inhibited compound 48/80-induced systemic anaphylaxis with doses of 10(-4) to 1 g/kg 1 h before anally administered. Of special note, SS-Tang inhibited systemic anaphylaxis completely with a dose of 1 g/kg. SS-Tang reduced plasma histamine levels induced by compound 48/80 significantly. However, the mortality was 100% when SS-Tang was administered after compound 48/80 treatment. SS-Tang (10(-1) g/kg) also inhibited passive cutaneous anaphylaxis activated by anti-dinitrophenyl IgE antibody by 30.9%. These results provide evidence that anal therapy of SS-Tang may be beneficial in the treatment of systemic and local anaphylaxis. PMID:10466085

Kim, H M; Kim, Y Y; Jang, H Y; Moon, S J; An, N H

1999-08-01

26

The rubber band revisited: Wang-Landau simulation  

NASA Astrophysics Data System (ADS)

In this work we apply Wang-Landau simulations to a simple model which has exact solutions both in the microcanonical and canonical formalisms. The simulations were carried out by using an updated version of the Wang-Landau sampling. We consider a homopolymer chain consisting of N monomers units which may assume any configuration on the two-dimensional lattice. By imposing constraints to the moves of the polymers we obtain three different models. Our results show that updating the density of states only after every N monomer moves leads to a better precision. We obtain the specific heat and the end-to-end distance per monomer and test the precision of our simulations by comparing the location of the maximum of the specific heat with the exact results and conventional Wang-Landau simulations for the three types of walk.

Ferreira, Lucas S.; Caparica, Álvaro A.; Neto, Minos A.; Galiceanu, Mircea D.

2012-10-01

27

CHEMICAL CHARACTERIZATION OF MUTAGENIC FRACTIONS OF PARTICLES FORM INDOOR COAL COMBUSTION: A STUDY OF LUNG CANCER IN XUAN WEI, CHINA  

EPA Science Inventory

In the rural Xuan Wei County, Yunnan Province, women's lung cancer mortality rates are among the highest in China. ost of these women are nonsmokers and studies have shown that lung cancer in Xuan Wei is associated with domestic use of smoky coal under unvented conditions. o inve...

28

CHEMICAL CHARACTERIZATION OF INDOOR AIR OF HOMES FROM COMMUNES IN XUAN WEI, CHINA, WITH HIGH LUNG CANCER MORTALITY RATES  

EPA Science Inventory

The paper discusses the chemical characterization of indoor air of homes from communes in Xuan Wei, China, with a high lung cancer mortality rate. (NOTE: In Xuan Wei, a rural county, the lung cancer mortality rate is among China's highest, especially in women. This mortality rate...

29

Utility of Wang needle aspiration in the diagnosis of actinomycosis.  

PubMed

An 85-year-old man had a 4-year history of recurrent pneumonia with a persistent pleural effusion. He underwent repeated bronchoscopy that revealed a right bronchus intermedius mass, but bronchial washes and biopsies remained nondiagnostic. A repeat bronchoscopy was performed, and a Wang needle aspiration of the mass was obtained that showed sulfur granules, diagnosing actinomycosis. The patient was started on appropriate antibiotic therapy. Actinomycosis must be considered in a patient with recurrent pneumonia and an endobronchial mass. Wang needle aspiration via bronchoscopy may be an important diagnostic tool. PMID:11399737

Bakhtawar, I; Schaefer, R F; Salian, N

2001-06-01

30

Bojungikki-Tang for Cancer-Related Fatigue: A Pilot Randomized Clinical Trial  

Microsoft Academic Search

Background: Bojungikki-tang (Bu-Zhong-Yi-Qi-Tang in Chinese or Hochu-ekki-to in Japanese) is a widely used herbal prescription in traditional medicine in China, Japan, and Korea. The aim of this study was to investigate the effectiveness of Bojungikki-tang for cancer-related fatigue. Methods: A total of 40 patients with cancer-related fatigue were randomized into an experimental or a waiting list control group. Patients in

Jong Soo Jeong; Bong Ha Ryu; Jin Sung Kim; Jae Woo Park; Won Cheol Choi; Seong Woo Yoon

2010-01-01

31

Strength-based Supervision: Frameworks, Current Practice, and Future Directions A Wu-wei Method.  

ERIC Educational Resources Information Center

|Discusses a method of counseling supervision similar to the wu-wei practice in Zen and Taoism. Suggests that this strength-based method and an understanding of isomorphy in supervisory relationships are the preferred practice for the supervision of family counselors. States that this model of supervision potentiates the person-of-the-counselor.…

Edwards, Jeffrey K.; Chen, Mei-Whei

1999-01-01

32

Lung Cancer and Indoor Exposure of Unvented Coal and Wood Combustion Emissions in Xuan Wei, China.  

National Technical Information Service (NTIS)

Residents of Xuan Wei County in China have unusually high lung cancer mortality that cannot be attributed to tobacco use or occupational exposure. They are exposed to smoke from unvented, open pit coal or wood fires (often used for cooking and heating). T...

J. L. Mumford R. S. Chapman D. B. Harris X. Z. He S. R. Cao

1987-01-01

33

LUNG CANCER AND INDOOR EXPOSURE OF UNVENTED COAL AND WOOD COMBUSTION EMISSIONS IN XUAN WEI, CHINA  

EPA Science Inventory

Residents of Xuan Wei County in China have unusually high lung cancer mortality that cannot be attributed to tobacco use or occupational exposure. They are exposed to smoke from unvented, open pit coal or wood fires (often used for cooking and heating). The variation in lung canc...

34

Review of Anhoplocampa Wei (Hymenoptera, Tenthredinidae), with description of a new species and a new combination  

PubMed Central

Abstract Anhoplocampa is redescribed based on new material. Anhoplocampa bicoloricornis sp. n. from China is described. Anhoplocampa yunanensis (Haris & Roller, 1999), comb. n. is transferred from Trichiocampus. A key to species of Anhoplocampa is provided. The differences between Anhoplocampa and Trichiocampus Hartig, 1837, Priophorus Dahlbom, 1835, Hoplocampa Hartig, 1837 and Renonerva Wei & Nie, 1998 are briefly discussed.

Wei, Meicai; Niu, Gengyun

2011-01-01

35

Epidemiology of lung cancer in Xuan Wei, China: current progress, issues, and research strategies  

SciTech Connect

In Xuan Wei, a rural Chinese county of about one million people, females' annual lung cancer mortality is China's highest, and males' is among China's highest. Xuan Wei's very high indoor air pollution levels (sometimes exceeding 20 mg/m3), residentially stable population, relatively uncomplicated lifestyle, and wide geographic variation in lung cancer mortality render it highly amenable to quantitative, interdisciplinary investigation of chemical carcinogens due to indoor air pollution. To date, epidemiologic findings reveal a closer association of lung cancer with the indoor burning of smoky coal (as opposed to smokeless coal or wood) than with tobacco use or occupation. Current aerometric, chemical, and toxicologic findings tend to confirm this association, though the specific carcinogenic constituents of Xuan Wei indoor air pollution have not yet been determined. Chinese and American investigators are conducting interdisciplinary field and laboratory investigations to quantify the lung cancer risk attendant on indoor air pollution relative to other factors, to measure and compare the characteristics of pollution from different Xuan Wei fuels, to determine the relative etiologic importance of pollution composition and concentration, and to develop quantitative relationships between air pollution dose and lung cancer risk.

Chapman, R.S.; Mumford, J.L.; Harris, D.B.; He, Z.Z.; Jiang, W.Z.; Yang, R.D.

1988-03-01

36

POLYMORPHISMS IN THE DNA NUCLEOTIDE EXCISION REPAIR GENES AND LUNG CANCER RISK IN XUAN WEI, CHINA  

EPA Science Inventory

The lung cancer mortality rate in Xuan Wei County, China is among the highest in the country and has been etiologically attributed to exposure to indoor smoky coal emissions that contain very high levels of polycyclic aromatic hydrocarbons (PAHs). Nucleotide excision repair (NE...

37

CORRIGENDUM: Prospects for a new boson W+/-1 in the minimal Higgsless model at the LHC Prospects for a new boson W+/-1 in the minimal Higgsless model at the LHC  

NASA Astrophysics Data System (ADS)

The author list originally given in the above article (Ming-Shui Chen, Jian-Guo Bian, Guo-Ming Chen, Hong-Jian He, Chun-Hua Jiang, Zu-Hao Li, Song Liang, Xiang-Wei Meng, Yong-Hui Qi, Zhi-Cheng Tang, Jun-Quan Tao, Zheng Wang, Jian Wang, Jian Wang, Xian-You Wang, Jian-Xiong Wang, Hong Xiao, Min Yang, Jing-Jing Zang, Bin Zhang, Zhen Zhang and Zhen- Xia Zhang) is incorrect. The correct author list is: Ming-Shui Chen, Jian-Guo Bian, Guo-Ming Chen, Chun-Hua Jiang, Zu-Hao Li, Song Liang, Xiang-Wei Meng, Zhi-Cheng Tang, Jun-Quan Tao, Zheng Wang, Jian Wang, Jian Wang, Xian-You Wang, Jian-Xiong Wang, Hong Xiao, Min Yang, Jing-Jing Zang, Bin Zhang, Zhen Zhang and Zhen-Xia Zhang. Hong-Jian He and Yong-Hui Qi did not take part in the writing of this text and do not bear any responsibility for its contents. Also, reference [4] in the paper should be corrected to: [4] Hong-Jian He et al 2008 Phys. Rev. D 78 031701(R)

Chen, Ming-Shui; Bian, Jian-Guo; Chen, Guo-Ming; He, Hong-Jian; Jiang, Chun-Hua; Li, Zu-Hao; Liang, Song; Meng, Xiang-Wei; Qi, Yong-Hui; Tang, Zhi-Cheng; Tao, Jun-Quan; Wang, Zheng; Wang, Jian; Wang, Jian; Wang, Xian-You; Wang, Jian-Xiong; Xiao, Hong; Yang, Min; Zang, Jing-Jing; Zhang, Bin; Zhang, Zhen; Zhang, Zhen-Xia

2009-12-01

38

Antithrombotic and antiplatelet activities of Soshiho-tang extract  

PubMed Central

Background Soshiho-tang (SH; Chinese name, Xiao-Chai-Hu-Tang; Japanese name, Shosaiko-to) is a traditional Korean, Chinese, and Japanese medicine, which has been used to treat various conditions, including hepatitis, liver cirrhosis, and chronic and acute liver disease. SH consists of seven herbal components, of which Scutellaria baicalensis Georgi and Zingiber officinale Roscoe, are reported to have antithrombotic and antiplatelet activities. We investigated the antithrombotic activity of SH, including S. baicalensis and Z. officinale, as an integrative therapy. Methods To identify the antithrombotic activity of SH, we used a FeCl3-induced thrombus formation model. The mechanism of SH-mediated antithrombotic activity was assessed by determining platelet aggregation and coagulation times ex vivo, washed platelet aggregation, serotonin secretion, and thromboxane B2 formation. Results SH prolonged the occlusion time of thrombus formation when applied in a FeCl3-induced thrombus formation model. SH also inhibited collagen-induced platelet aggregation ex vivo in a concentration-dependent manner; however, it did not affect coagulation. Hence, to identify the antiplatelet effect of SH, we investigated washed platelet aggregations in vitro. SH significantly inhibited various agonist-induced platelet aggregations, and it completely inhibited serotonin secretion and thromboxane B2 formation. Conclusions The findings suggest that SH inhibited FeCl3-induced thrombus formation through antiplatelet activity, including inhibition of platelet aggregation, and serotonin and TXB2 production. Thus, SH may be useful as an integrative herbal formula for the treatment of thrombosis.

2013-01-01

39

Generic, Hierarchical Framework for Massively Parallel Wang-Landau Sampling  

NASA Astrophysics Data System (ADS)

We introduce a parallel Wang-Landau method based on the replica-exchange framework for Monte Carlo simulations. To demonstrate its advantages and general applicability for simulations of complex systems, we apply it to different spin models including spin glasses, the Ising model, and the Potts model, lattice protein adsorption, and the self-assembly process in amphiphilic solutions. Without loss of accuracy, the method gives significant speed-up and potentially scales up to petaflop machines.

Vogel, Thomas; Li, Ying Wai; Wüst, Thomas; Landau, David P.

2013-05-01

40

On complete integrability of the Mikhailov-Novikov-Wang system  

NASA Astrophysics Data System (ADS)

In the present paper we consider a new two-component fifth-order integrable system recently found by Mikhailov, Novikov, and Wang, and show that this system possesses a hereditary recursion operator and infinitely many commuting symmetries and conservation laws, as well as infinitely many compatible Hamiltonian and symplectic structures, and is therefore completely integrable. The system in question admits a reduction to the Kaup-Kupershmidt equation.

Voj?ák, Petr

2011-04-01

41

Redescription and systematic status of Neocapillaria phoxini Yu et Wang, 1994 (Nematoda: Capillariidae).  

PubMed

Re-examination of the syntypes of the capillariid nematode Neocapillaria phoxini Yu et Wang, 1994, the type species of Neocapillaria Yu et Wang, 1994, described from the intestine of the freshwater fish Phoxinus lagowskii variegatus Günther (Cyprinidae) from China, confirmed its morphological similarity with species of Freitascapillaria Moravec, 1987, to which it is transferred as Freitascapillaria phoxini (Yu et Wang, 1994) comb. n. Consequently, Neocapillaria Yu et Wang, 1994 (a homonym to Neocapillaria Moravec, 1987) and Sinocapillaria Moravec et Spratt, 1998 become junior synonyms of Freitascapillaria. Skrjabinocapillaria gigantea is transferred to Freitascapillaria as F. gigantea (Wang, 1984) comb. n. PMID:19175211

Moravec, Frantisek; Nie, Pin; Wang, Guitang

2008-12-01

42

Effects of Lizhong Tang on cultured mouse small intestine interstitial cells of Cajal  

PubMed Central

AIM: To investigate the effects of Lizhong Tang, an herbal product used in traditional Chinese medicine, on mouse small intestine interstitial cells of Cajal (ICCs). METHODS: Enzymatic digestions were used to dissociate ICCs from mouse small intestine tissues. The ICCs were morphologically distinct from other cell types in culture and were identified using phase contrast microscopy after verification with anti c-kit antibody. A whole-cell patch-clamp configuration was used to record potentials (current clamp) from cultured ICCs. All of the experiments were performed at 30-32??°C. RESULTS: ICCs generated pacemaker potentials, and Lizhong Tang produced membrane depolarization in current-clamp mode. The application of flufenamic acid (a nonselective cation channel blocker) abolished the generation of pacemaker potentials by Lizhong Tang. Pretreatment with thapsigargin (a Ca2+-ATPase inhibitor in the endoplasmic reticulum) also abolished the generation of pacemaker potentials by Lizhong Tang. However, pacemaker potentials were completely abolished in the presence of an external Ca2+-free solution, and under this condition, Lizhong Tang induced membrane depolarizations. Furthermore, When GDP-?-S (1 mmol/L) was in the pipette solution, Lizhong Tang still induced membrane depolarizations. In addition, membrane depolarizations were not inhibited by chelerythrine or calphostin C, which are protein kinase C inhibitors, but were inhibited by U-73122, an active phospholipase C inhibitors. CONCLUSION: These results suggest that Lizhong Tang might affect gastrointestinal motility by modulating pacemaker activity in interstitial cells of Cajal.

Hwang, Min Woo; Kim, Jung Nam; Song, Ho Jun; Lim, Bora; Kwon, Young Kyu; Kim, Byung Joo

2013-01-01

43

[Study on screening cardioprotective components from Zhishi Xiebai Guizhi Tang].  

PubMed

Zhishi Xiebai Guizhi Tang (ZSXBGZT), a famous traditional Chinese formula from Synopsis of Golden Chamber, composing of five herbal medicines, has been routinely used for the therapy of cardiovascular diseases in clinical. However, the active components of ZSXBGZT have not been investigated thoroughly. A reliable cell model was established by H2O2-induced injury in neonatal rat cardiomyocytes (NRCMs), with fluorescein diacetate (FDA) labelling the live cells, to screen cardioprotective substances. Seven components were found to have obvious cardioprotective effects through screening ZSXBGZT, Vc as the positive control. Eleven compounds were identified by liquid chromatography-mass spectrometry (LC-MS) from the active components C18, D14, D15, D16 and E09, and 6 of them were investigated further, which showed that hesperidin, neohesperidin and eriodictyol could protect NRCMs from H2O2-induced injury. In particular, eriodictyol showed significant cardioprotective effects in a dose-response relationship. PMID:23947146

Wang, Cheng; Zhang, Yu-Feng; Zhao, Xiao-Ping

2013-05-01

44

Beyond Tang: The Hidden Benefits of the Space Program  

ScienceCinema

Most people are familiar with the advertisement touting Tang as the orange drink that the astronauts took to the Moon. However, many other products have resulted from the space program, as well as discoveries with applications to everyday life. NASA highlights these products and information in an annual publication entitled 'Spinoffs'. Bar coding, medical imaging, suits worn by fire-fighters, smoke detectors, and thermal gloves and boots are all examples of products resulting from technologies developed in support of the space program. Detection of the 750K surface temperature of Venus in the 1960's led to the realization that the greenhouse effect (or 'global warming') is a real physical manifestation and resulted in concerns about our own terrestrial environment. Debate about the possibility of underground life on Mars spurred investigations which found organisms living inside rocks on the Earth. These spinoffs and more will be discussed.

45

Beyond Tang: The Hidden Benefits of the Space Program  

SciTech Connect

Most people are familiar with the advertisement touting Tang as the orange drink that the astronauts took to the Moon. However, many other products have resulted from the space program, as well as discoveries with applications to everyday life. NASA highlights these products and information in an annual publication entitled 'Spinoffs'. Bar coding, medical imaging, suits worn by fire-fighters, smoke detectors, and thermal gloves and boots are all examples of products resulting from technologies developed in support of the space program. Detection of the 750K surface temperature of Venus in the 1960's led to the realization that the greenhouse effect (or 'global warming') is a real physical manifestation and resulted in concerns about our own terrestrial environment. Debate about the possibility of underground life on Mars spurred investigations which found organisms living inside rocks on the Earth. These spinoffs and more will be discussed.

Barlow, Nadine (Northern Arizona University)

2005-05-25

46

Orszag Tang vortex - Kinetic study of a turbulent plasma  

SciTech Connect

Kinetic evolution of the Orszag-Tang vortex is studied using collisionless hybrid simulations based on particle in cell ions and fluid electrons. In magnetohydrodynamics (MHD) this configuration leads rapidly to broadband turbulence. An earlier study estimated the dissipation in the system. A comparison of MHD and hybrid simulations showed similar behavior at large scales but substantial differences at small scales. The hybrid magnetic energy spectrum shows a break at the scale where Hall term in the Ohm's law becomes important. The protons heat perpendicularly and most of the energy is dissipated through magnetic interactions. Here, the space time structure of the system is studied using frequency-wavenumber (k-omega) decomposition. No clear resonances appear, ruling out the cyclotron resonances as a likely candidate for the perpendicular heating. The only distinguishable wave modes present, which constitute a small percentage of total energy, are magnetosonic modes.

Parashar, T. N.; Servidio, S.; Shay, M. A.; Matthaeus, W. H. [Department of Physics and Astronomy, 217 Sharp Lab, University of Delaware, Newark, Delaware 19716 (United States); Cassak, P. A. [Department of Physics and Astronomy, 217 Sharp Lab, University of Delaware, Newark, Delaware 19716 (United States); Department of Physics, Hodges Hall, Box 6315, West Virginia University, Morgantown, WV 26506 (United States)

2010-03-25

47

Convergence for the Wang-Landau Density of States  

SciTech Connect

The Wang-Landau method of estimating the density of states, g (E), has become a powerful tool in statistical mechanics. Here it is shown that the distribution of random walkers sampled using an estimated density of states can always be used to improve the estimate. Specifically, this can be done without resorting to an auxiliary modification factor, f, which previously has been been used to find g (E) self consistently through a procedure that reduces f incrementally towards unity. The new, straight-forward approach is validated for multiple, independent random walkers.

Brown, Greg [ORNL; Odbadrakh, Khorgolkhuu [ORNL; Nicholson, Don M [ORNL; Eisenbach, Markus [ORNL

2011-01-01

48

Wang-Landau Simulations of Adsorbed and Confined Lattice Proteins  

NASA Astrophysics Data System (ADS)

The hydrophobic-polar (HP) model has emerged as one of the standard approaches for simulating protein folding. In this work, we used this model together with Wang-Landau (WL) sampling and appropriate Monte Carlo trial moves to determine the density of states and thermodynamics for two cases: Protein adsorption and protein confinement, in the vicinity of attractive surfaces. The influence on the adsorption behavior of surface attractive strength in the adsorption case and volumetric spaces in the confinement case will be discussed.

Pattanasiri, Busara; Li, Ying Wai; Landau, David P.; Wüst, Thomas

2012-08-01

49

Effect of Wen-Pi-Tang extract on lung damage by influenza virus infection  

Microsoft Academic Search

The effect of Wen-Pi-Tang extract on influenza virus infection in mice was investigated. The administration of Wen-Pi-Tang extract at a dose of 100mg\\/kg body wt. for 8 consecutive days to influenza virus-infected mice reversed the lack of body wt. gain and prevented the increase in lung weight caused by the infection in comparison with uninfected mice, while allopurinol, a xanthine

T. Yokozawa; M. Sekiya; E. J. Cho; M. Kurokawa; K. Shiraki

2004-01-01

50

[High performance liquid chromatographic fingerprints of Baihe Zhimu Tang and its correlation to single herb].  

PubMed

The high performance liquid chromatographic (HPLC) fingerprints of Baihe Zhimu Tang were established for evaluating the effective substance basis and compatibility regulation of Baihe Zhimu Tang. An Agela Venusil XBP-C18 column (250 mm x 4.6 mm, 5 microm) was employed, and the gradient elution of acetonitrile and 0. 1% formic acid was used as mobile phase with a flow rate of 1 mL/min, the detection wavelength was set at 315 nm, and the column temperature was set at 25 degrees C. By taking mangiferin as the reference substance, the fingerprints of 10 batches of Baihe Zhimu Tang prepared by Bulbus Lilii and Rhizoma Anemarrhenae from different producing areas were analyzed under the same chromatographic conditions. The results showed that there were 16 common peaks contained in the tested samples. Five constituents were identified as 5-hydroxymethyl-2-furaldehyde (5-HMF), neomangiferin, mangiferin, isomangiferin and regaloside B by comparing the retention times and ultraviolet spectra of the peaks with those of the reference substances. The HPLC fingerprints of Baihe Zhimu Tang established with the above method show good characteristic and repeatability, and the method is stable and reliable, it can be used for the quality control of Baihe Zhimu Tang. The main chromatographic peaks of the HPLC fingerprints of Baihe Zhimu Tang were identified in the experiment and also 5-HMF was identified as the main constituent which changed significantly in decocting process. PMID:20352931

Qin, Kunming; Fang, Qianbo; Cai, Hao; Li, Weidong; Cai, Baochang

2009-11-01

51

Ke Wang, a Chinese television soap opera with a message.  

PubMed

The Chinese soap opera, Ke Wang, was created by Li Xiaoming between August 1989 and June 1990 and produced at a cost of US$4650 per episode. The characters were drawn from everyday ordinary Chinese life: a traditional and open-minded and caring woman, a typical mother who works hard and loves her children, a highly educated upwardly mobile man who divorces his wife, a professor criticized during the Cultural Revolution, a doctor prejudiced against ordinary people, a kind honest man who marries the divorcee, a friend of the divorcee, a man who is optimistic in spite of bad experiences during the Cultural Revolution, and an excellent medical doctor who also resolves conflicts. The program was very popular, even among Communists, because of its value-based content, the real-life nature of the show, the change from highly restricted programming, the elaborate and supportive media coverage, and dialogue which closely matches audience preferences. The show has been aired by over 100 stations to date and has reached a total estimated audience of 550 million. The sale of television sets has increased since the show's appearance. The script reflects the conflicts between traditional and modern Chinese values. Pro-social values and behaviors are learned from the role models depicted; examples are given of immediate social impact. Ke Wang was a by-product of the Beijing Television Arts Center's interest in designing television programs that are relevant to the lives of ordinary people. The 60-minute scripts dealt with issues such as the status of women, social morality, family harmony, class conflict, responsible parenthood, maintenance of traditional culture, volunteerism, child development, and coping with physical disability. The Chinese government hailed Ke Wang as model television and awarded US$20,000 in prize money to the producers. The Chinese government is planning to produce other entertainment-education soap operas, which raises the problem of blatant, political propaganda. In 1989, after the Tinanmen Square events, the controversial He Shang, which attacked cultural symbols, was denounced and banned. PMID:12286006

Wang, M; Singhal, A

1992-01-01

52

Multiple Walkers in the Wang-Landau Algorithm  

SciTech Connect

The mean cost for converging an estimated density of states using the Wang-Landau algorithm is measured for the Ising and Heisenberg models. The cost increases in a power-law fashion with the number of spins, with an exponent near 3 for one-dimensional models, and closer to 2.4 for two-dimensional models. The effect of multiple, simultaneous walkers on the cost is also measured. For the one-dimensional Ising model the cost can increase with the number of walkers for large systems. For both the Ising and Heisenberg models in two-dimensions, no adverse impact on the cost is observed. Thus multiple walkers is a strategy that should scale well in a parallel computing environment for many models of magnetic materials.

Brown, G

2005-12-28

53

Sampling along reaction coordinates with the Wang-Landau method  

NASA Astrophysics Data System (ADS)

The multiple range random walk algorithm recently proposed by Wang and Landau [2001, Phys. Rev. Lett ., 86 , 2050] is adapted to the computation of free energy profiles for molecular systems along reaction coordinates. More generally, we show how to extract partial averages in various statistical ensembles without invoking simulations with constraints, biasing potentials or unknown parameters. The method is illustrated on a model 10-dimensional potential energy surface, for which analytical results are obtained. It is then applied to the potential of mean force associated with the dihedral angle of the butane molecule in the gas phase and in carbon tetrachloride solvent. Finally, isomerization in a small rocksalt cluster, (NaF) 4 , is investigated in the microcanonical ensemble, and the results are compared to those of parallel tempering Monte Carlo.

Calvo, F.

54

Generic parallel Wang-Landau sampling for complex systems  

NASA Astrophysics Data System (ADS)

We introduce a parallel realization for Wang-Landau sampling in Monte Carlo simulations based on a replica-exchange framework. The key idea is to split the entire energy range of the system under consideration into several smaller, overlapping sub intervals. The survey of configurational phase space can then be distributed over multiple processors, with exchanges of random walkers taking place in the overlapping energy windows. To demonstrate the robustness and advantages of this parallel scheme for the simulations of complex systems, we have applied it to protein adsorption problems using the HP lattice protein modelfootnotetextK. A. Dill, Biochemistry 24, 1501 (1985).. The method gives significant speed-up and achieves strong scaling on small computer architectures like multi-core processors, with a possible improvement in accuracy. We believe that it could be potentially beneficial for large-scale petaflop machines.

Li, Ying Wai; Vogel, Thomas; Landau, David P.; Wüst, Thomas

2013-03-01

55

Lung cancer and indoor exposure of unvented coal and wood combustion emissions in Xuan Wei, china  

SciTech Connect

Residents of Xuan Wei County in China have unusually high lung cancer mortality that cannot be attributed to tobacco use or occupational exposure. They are exposed to smoke from unvented, open pit coal or wood fires (often used for cooking and heating). The variation in lung cancer rates among communes within the county suggests that indoor combustion of smoky coal may be the prime determinant of lung cancer. To characterize the air in Xuan Wei homes, samples of the air particles and semivolatile organics were collected from homes located in communes with different lung-cancer rates. Samples collected in the commune in which the lung-cancer rate is high and smoky coal is the predominant fuel-contained high concentrations of submicron particles with high organic content; organic extracts of these samples were mutagenic. Samples from homes in a wood-burning commune, which has a low lung-cancer rate, consisted mostly of larger particles of lower organic content and mutagenicity. The smoky coal sample was also a more potent skin-tumor initiator compared to the wood or smokeless coal sample and was a mouse skin carcinogen.

Mumford, J.L.; Chapman, R.S.; Harris, D.B.; He, X.Z.; Cao, S.R.

1987-05-01

56

Security Analysis of A Remote User Authentication Protocol by Liao and Wang  

Microsoft Academic Search

In Elsevier's journal of Computer Standards & Interfaces, 2007, Liao and Wang proposed an authentication protocol using smart card and claimed that their protocol provides security against replay attacks, active attacks and insider attacks. In addition, they argued that user anonymity is guaranteed. In this paper, we point out that Liao-Wang protocol is vulnerable to an insider attack by presenting

Dang Nguyen Du; Kwangjo Kim

2009-01-01

57

Shield of collaboration: The Wang Jingwei regime's security service, 1939–1945  

Microsoft Academic Search

This article studies the role of the security service in the Wang Jingwei collaborationist regime (1940–45), and argues that it not only contributed to the regime's coercive muscle but that it was also involved with the regime's broader socio-political policies. The central position within the Wang Jingwei government enjoyed by the security service enabled its head, Li Shiqun, to wield

Brian Martin

2001-01-01

58

Phonology and Reading: A Response to Wang, Trezek, Luckner, and Paul  

ERIC Educational Resources Information Center

|Four critical responses to an article, "The Role of Phonology and Phonologically Related Skills in Reading Instruction for Students Who Are Deaf or Hard of Hearing" (Wang, Trezek, Luckner, & Paul, 2008), are presented. Issue is taken with the conclusions of the article by Wang and colleagues regarding the "necessary" condition of phonological…

Allen, Thomas E.; Clark, M. Diane; del Giudice, Alex; Koo, Daniel; Lieberman, Amy; Mayberry, Rachel; Millerd, Paul

2009-01-01

59

[In vitro effect of Banxiaxiexin Tang and different conbinations on hepatic CYP450 in rats].  

PubMed

To study the effect of Banxiaxiexin Tang and different conbinations on CYP450 in rat liver microsomes, from the point of liver metabolism, evaluate significance of Banxiaxiexin Tang compatibility. The rats were randomly divided into five groups: Banxiaxiexin Tang group, pungent-swelling group, bitter-descending group, sweet-invigorating group and control group, which were all given decoction by gavage. Using liver microsomes in vitro incubation method, probe substrate were incubated and their metabolites was detected by ultra-high performance liquid chromatography, then was calculated metabolic rate to reflect the drug-treated liver microsomes CYP2C6, CYP2E1, CYP3A1/2 activity. The results showed that comparing with the control group, both Banxiaxiexin Tang group and bitter-descending group showed inhibition on all enzyme subtype (P < 0.01), pungent-swelling group showed significant inhibition on CYP2C6, but no inhibition on CYP2E1 and CYP3A1/2; sweet-invigorating group showed inhibition on CYP2C6 and CYP2E1, but no inhibition on CYP3A1/2. Compared the inhibition on CYP with the three conbinations, bitter-descending group was significant higher than other groups. Banxiaxiexin Tang group showed inhibition on rat liver microsomes CYP450, and the activity maybe come from bitter-descending group. PMID:23126207

Cai, Qiaoling; Cui, Bo; Wang, Ying; An, Rui; Wang, Xinhong; Ma, Yueming

2012-07-01

60

Chemical characterization of indoor air of homes from communes in Xuan Wei, China, with high lung cancer mortality rates  

EPA Science Inventory

In a rural county, Xuan Wei, China, the lung cancer mortality rate is among China's highest, especially in women. This mortality rate is more associated with indoor air burning of smoky coal, as opposed to smokeless coal or wood, for cooking and heating under unvented conditions....

61

INDOOR AIR EXPOSURE TO COAL AND WOOD COMBUSTION EMISSIONS IN XUAN WEI, CHINA, WITH A HIGH LUNG CANCER RATE  

EPA Science Inventory

Residents of Xuan Wei County in China have unusually high lung cancer mortality that cannot be attributed to tobacco use or occupational exposure. hey are exposed to smoke from unvented, open pit coal or wood fires (often used for cooking and heating). The variation in lung cance...

62

CHEMICAL CHARACTERIZATION OF INDOOR AIR HOMES FROM COMMUNES IN XUAN WEI, CHINA, WITH HIGH LUNG CANCER MORTALITY RATE  

EPA Science Inventory

In a rural county, Xuan Wei, China, the lung cancer mortality rate is among China's highest, especially in women. his mortality rate is more associated with indoor air burning of smoky coal, as opposed to smokeless coal or wood, for cooking and heating under unvented conditions. ...

63

Equivalence of the Wei potential model and Tietz potential model for diatomic molecules.  

PubMed

By employing the dissociation energy and the equilibrium bond length for a diatomic molecule as explicit parameters, we generate improved expressions for the well-known Rosen-Morse, Manning-Rosen, Tietz, and Frost-Musulin potential energy functions. It is found that the well-known Tietz potential function that is conventionally defined in terms of five parameters [T. Tietz, J. Chem. Phys. 38, 3036 (1963)] actually only has four independent parameters. It is shown exactly that the Wei [Phys. Rev. A 42, 2524 (1990)] and the well-known Tietz potential functions are the same solvable empirical function. When the parameter h in the Tietz potential function has the values 0, +1, and -1, the Tietz potential becomes the standard Morse, Rosen-Morse, and Manning-Rosen potentials, respectively. PMID:22779631

Jia, Chun-Sheng; Diao, Yong-Feng; Liu, Xiang-Jun; Wang, Ping-Quan; Liu, Jian-Yi; Zhang, Guang-Dong

2012-07-01

64

Wei-Wen Yu Center for Cold-Formed Steel Structures  

NSDL National Science Digital Library

Established at the University of Missouri-Rolla in 1990, the Center for Cold-Formed Steel Structures (CCFSS) was funded with an initial grant from the American Iron and Steel Institute. The Center was renamed in 2000 for its founding director, Dr. Wei-Wen Yu, and today the Center continues to "provide an integrated approach for handling research, teaching, engineering education, technical services, and professional activity." On their homepage, visitors will find five main sections, including "Resources", "Publications", and "Calendar". In the "Publications" section, users can look through past issues of their newsletter, table of contents from their proceedings from 1971 to 2002, and their technical bulletins from 1999 to the present. Moving on, the "Resources" contains a database of the Center's books, and equally importantly, a listing of relevant professional association websites. Finally, visitors can also sign up for email updates from the CCFSS and look over their upcoming conference events.

65

Efficient First-principles Wang-Landau Calculations  

NASA Astrophysics Data System (ADS)

The Wang-Landau (WL) method of finding the density of states g(E) contributing to the partition function Z(kT) is useful for determining thermodynamic properties from first-principles energy calculations for magnetic systems. Since DFT calculations require significant computer resources, it is important to make the convergence of the WL method to a self-consistent g(E) as efficient as possible. We present approaches for making accurate initial estimates of g(E) based on similar Hamiltonians or estimates of g(E) for a different number of atoms. These approaches can include workstation-based calculations using classical Heisenberg Hamiltonians based on exchange parameters calculated from initial data from DFT WL calculations. In addition, we annunciate serveral insights we have gained into the convergence of the WL method. For instance, the minimum curvature of the calculated g(E) is limited by the update parameter and the maximum energy step of the Markov chain. This material is based upon work supported as part of the Center for Defect Physics, an Energy Frontier Research Center funded by the U. S. Department of Energy, Office of Science, Office of Basic Energy Sciences. This research used resources of the Oak Ridge Leadership Computing Facility at Oak Ridge National Laboratory, which is supported by the Office of Science of the Department of Energy.

Brown, G.; Rusanu, A.; Odbadrakh, Kh.; Eisenbach, M.; Nicholson, D. M.

2011-03-01

66

[Mr. Wang Le-ting: a master of acupuncture].  

PubMed

Mr. WANG Le-ting attaches great importance to accurate differentiation of syndromes, strict selection of acupoints, technique and direction of needle insertion, clear reinforcing and reducing methods after the appearance of needling sensations, proper opportunities of manipulations as well as needle withdrawal techniques, and reasonable application of acupuncture and moxibustion respectively. The above mentioned principles are known as his "5 agreements". He emphasizes that the selection of acupoints should be "in accordance with both the meridians and the accurate location of the points", and "needling sensation is necessary for each point". He holds that the back-shu points of the five-zang organs and Geshu (BL 17) can be adopted for patient with deficiency of qi, blood, yin and yang. In the aspect of acupoint theory, he insists the accurate location of Xuanzhong (GB 39). He also adjusts the locations of Huatuo Jiaji (EX-B 2) points, and finds the location of the new Dubi (ST 35). For easier applications, he divides the functions of acupoints into different schools of qi, blood, cold, heat, deficiency, excess, wind and dampness. And 41 combinations of acupoints are also invented as innovation. He is always strict to his students, instructing and influencing them by his own words and deeds. He is always conscientious and meticulous, which benefit immensely his followers, and remains a lot of precious experiences for the later generations. PMID:23214000

Niu, Xue-Song; Wang, Fan

2012-11-01

67

Study on the provenance and elemental distribution in the glaze of Tang Sancai by proton microprobe  

NASA Astrophysics Data System (ADS)

In order to study the provenance and the composition of the colorants, different parts and colors of the glazes of Tang Sancai of three kilns were measured using proton microprobe. The analytical results show that distribution of Al, Si, K, Ca, Ti and Pb is homogeneous in the glaze. Fe is the main colorant element of yellow color, while Cu is the main colorant element of green color. The brown color is due to the mixture of compounds based on Fe and Cu. It was also found that the contents of K, Si and Pb are different for Tang Sancai of different provenance, which indicates they may be used for discrimination of provenance.

Feng, X. Q.; Feng, S. L.; Sha, Y.; Jakši?, M.

2005-04-01

68

Rap and Resistance: A Social Movement of the Wu-Tang Clan.  

ERIC Educational Resources Information Center

|Examines specific collective identity and political expression of the rap group the Wu-Tang Clan. Reveals a multi-layered political strategy that has been conscientiously designed and implemented to instigate a social movement. Prioritizes the voices of marginalized Black peoples and provides raw narratives about oppression. (MMU)|

Chasteen, Amy L.; Shriver, Thomas

1998-01-01

69

The alteration of components in the fermented Hwangryunhaedok-tang and its neuroprotective activity  

PubMed Central

Background: Hwangryunhaedok-tang is a traditional herbal prescription that has sedative activity, hypotensive and anti-bacterial effects. Objective: In this study, we investigated the alteration of contents of components in Hwangryunhaedok-tang, antioxidant activity and neuroprotective activity by fermentation with Lactobacillus acidophilus KFRI 128. Materials and Methods: Contents of three marker compounds (geniposide, berberine and palmatine) and unknown compounds in the Hwangryunhaedok-tang (HR) and the fermented Hwangryunhaedok-tang (FHR) were measured and compared using the established high-performance liqued chromatograph coupled with a photodiode (HPLC-DAD) method. The antioxidant activity of HR and FHR were determined by DPPH free radical and hydrogen peroxide (H2O2) scavenging assay. Also, the neuroprotective activities of HR and FHR against glutamate-induced oxidative stress in a mouse hippocampal cell line (HT22) were evaluated by MTT assay. Results: The contents of geniposide and palmatine were decreased but the content of berberine was increased in the FHR. And the contents of unknown compounds (1), (2), (3), (4) and (5) in the HR were altered by fermentation. Electron donating activity (EDA, %) value of FHR was higher than HR for DPPH radical scavenging activity and H2O2 scavenging activity, respectively. In the MTT assay, FHR showed more potent neuroprotective activity than HR by 513.90%. Conclusion: The FHR using microorganism could convert compounds in HR and enhance the antioxidant and neuroprotective activity.

Yang, Hye Jin; Weon, Jin Bae; Lee, Bohyoung; Ma, Choong Je

2011-01-01

70

Inside out: creating the exotic within early Tang dynasty China in the seventh and eighth centuries  

Microsoft Academic Search

Highly coloured, lead glazed ceramic vessels of the early Tang period, known as sancai, or three colour ware, take on unusual shapes and decoration often reminiscent of earlier metalwork from Iran. The paper examines possible sources of this flamboyant and apparently outside appearance to argue that the sancai was not directly based on Iranian metal work or ceramics. Rather the

Jessica Rawson

2012-01-01

71

A note on Wang et al's attack on Zhang et al's multiparty quantum secret sharing  

NASA Astrophysics Data System (ADS)

Recently, Wang et al (2008 Phys. Lett. A 373 65) proposed an attack on Zhang et al's (2007 Opt. Commun. 269 418) multiparty quantum secret sharing scheme, in which the first and the last agent are reported to be able to cooperatively eavesdrop on all the secret messages without being detected. In this paper, we show that in Wang et al's attack, on average no more than half the secret messages can be eavesdropped.

Gao, Gan

2012-08-01

72

PGPR mediated management of stem blight of Phyllanthus amarus (Schum and Thonn) caused by Corynespora cassiicola (Berk and Curt) Wei  

Microsoft Academic Search

Bacillus subtilis (BSCBE4), Pseudomonas chlororaphis (PA23), endophytic P. fluorescens (ENPF1) inhibited the mycelial growth of stem blight pathogen Corynespora casiicola (Berk and Curt)Wei under in vitro. All these bacterial isolates produced both hydroxamate and carboxylate type of siderophores. But the siderophore production was maximum with the isolate ENPF1. Delivering of talc based formulation of BSCBE4 through seedling dip and foliar

S Mathiyazhagan; K Kavitha; S Nakkeeran; G Chandrasekar; K Manian; P Renukadevi; AS Krishnamoorthy; WGD Fernando

2004-01-01

73

Mutagenicity, carcinogenicity, and human cancer risk from indoor exposure to coal and wood combustion in xuan wei, china  

SciTech Connect

The residents in Xuan Wei County, China, have been exposed to high levels of combustion emissions from smoky and smokeless coal and wood combustion under unvented conditions in homes. An unusually high lung cancer mortality rate that can not be attributed to tobacco smoke or occupational exposure was found. The communes using smoky coal, which emits more organics than smokeless coal, generally have a higher lung cancer rate than the communes using smokeless coal or wood. The mutagenicity and carcinogenicity of organic extracts of indoor air particles collected from Xuan Wei homes during cooking were investigated. The objectives of the study were (1) to investigate the characteristics of lung cancer mortality in Xuan Wei, (2) to determine the genotoxicity and chemical and physical properties of the combustion emissions, and (3) to link bioassay results to human lung cancer data. The organic extracts of these emission particles were tested for mutagenicity in the Ames Salmonella and the L5178Y TK+/- mouse lymphoma assays and for skin tumor-initiating activity and complete carcinogenicity in SENCAR mice. The two coal samples showed higher activity in both mutagenicity and tumor initiation. When the emission rate of organics was taken into consideration, the smoky coal emission showed the highest potency of the three fuels. The smoky coal sample was also a more potent complete carcinogen than the wood sample. Higher mutagenicity and carcinogenicity of the smoky coal emission compared to wood or smokeless coal emissions are in agreement with the epidemiological data.

Mumford, J.L.; Chapman, R.S.; Nesnow, S.; Helmes, C.T.; Li, X.

1990-01-01

74

[Treatment of intestinal metaplasia and atypical hyperplasia of gastric mucosa with xiao wei yan powder].  

PubMed

138 cases of intestinal metaplasia (IM) and 104 cases of atypical hyperplasia (AH) of the gastric mucosa of chronic gastritis treated with Xiao Wei Yan Powder (XWYP) were reported. The diagnoses were based on the pathological examination of gastric antrum biopsy specimens. The cases were randomly divided into treated group and control group. The XWYP contained Smilax glabrae, Hedyotis diffusae, Taraxacum mongolicum, Caesalpinia sappan, Paeonia alba, Cyperus rotundus, Bletilla striata, Glycyrrhiza uralensis etc., and was prepared in powder form, taken orally 5-7g tid. After 2-4 months of administration, gastroscopic and pathological examinations were repeated. Results: In treated group, the total effective rate of IM was 91.3% and that of the AH was 92.16%, while in control group, they were 21.3% and 14.46% respectively (P < 0.01). It denoated that XWYP had marked therapeutic effects for IM and AH. The animal experiments revealed no toxic effect, so safety guarantee was provided for its clinical application. PMID:1302542

Liu, X R; Han, W Q; Sun, D R

1992-10-01

75

March 17 - 19, 2004: Proteomics: Finding the Needle in the Haystack, Xuena Wang, Kith Pradhan, Chen Ji, Xiangfeng Wu, Yeming Ma, Wei Zhu, Piyush Kumar, Valentin Polishchuk, Olaf Hall-Holt, Joseph Mitchell, Estie, Arkin, James Glimm, John Kovach  

Cancer.gov

Cosine Dimension Reduction Cosine Dimension Reduction 1000 2000 3000 4000 5000 6000 7000 8000 9000 10000 11000 1 00 2 00 3 00 4 00 5 00 0.5 1 1.5 2 2.5 3 x 10 4 0 1 00 2 00 3 00 4 00 Original (368750) Reduced (32768) VII. VII.

76

Impact of climate change and anthropogenic activities on stream flow and sediment discharge in the Wei River basin, China  

NASA Astrophysics Data System (ADS)

Reduced stream flow and increased sediment discharge are a major concern in the Yellow River basin of China, which supplies water for agriculture, industry and the growing populations located along the river. Similar concerns exist in the Wei River basin, which is the largest tributary of the Yellow River basin and comprises the highly eroded Loess Plateau. Better understanding of the drivers of stream flow and sediment discharge dynamics in the Wei River basin is needed for development of effective management strategies for the region and entire Yellow River basin. In this regard we analysed long-term trends for water and sediment discharge during the flood season in the Wei River basin, China. Stream flow and sediment discharge data for 1932 to 2008 from existing hydrological stations located in two subcatchments and at two points in the Wei River were analysed. Precipitation and air temperature data were analysed from corresponding meteorological stations. We identified change-points or transition years for the trends by the Pettitt method and, using double mass curves, we diagnosed whether they were caused by precipitation changes, human intervention, or both. We found significant decreasing trends for stream flow and sediment discharge during the flood season in both subcatchments and in the Wei River itself. Change-point analyses further revealed that transition years existed and that rapid decline in stream flow began in 1968 (P < 0.01), and that sediment discharge began in 1981 (P < 0.01) in the main river. In the two subcatchments, the transition years were 1985 (P < 0.01) and 1994 (P < 0.05) for water discharge, and 1978 and 1979 for sediment discharge (P < 0.05), respectively. The impact of precipitation or human activity on the reduction amount after the transition years was estimated by double mass curves of precipitation vs. stream flow (sediment). For reductions in stream flow and sediment discharge, the contribution rate of human activity was found to be 82.80 and 95.56%, respectively, and was significantly stronger than the contribution rate of precipitation. This evidence clearly suggests that, in the absence of significant decreases in precipitation, strategies for managing the region need to focus on human activities to control erosion without restricting stream flow.

Gao, P.; Geissen, V.; Ritsema, C. J.; Mu, X.-M.; Wang, F.

2013-03-01

77

The merchants of chang’an in the Sui and Tang dynasties  

Microsoft Academic Search

As the capital of the Sui and Tang dynasties, Chang’an brought together large numbers of high-ranking officials, aristocrats,\\u000a local residents, and sojourners. The promise of profits caused by the high demand for consumer goods attracted merchants.\\u000a Chang’an was also the starting point of the renowned Silk Road. For all these reasons, Chang’an became a gathering point for\\u000a Small and medium-scale

Xue Pingshuan

2006-01-01

78

Sopungyangjae-Tang Inhibits Development of Dermatitis in Nc\\/Nga Mice  

Microsoft Academic Search

Sopungyangjae-Tang (SYT) is a traditional Korean decoction used for the treatment of dermatitis. The aim of this study was to confirm whether or not SYT has a preventive effect on the development of atopic dermatitis in dinitrochlorobenzene-applied Nc\\/Nga mice. SYT was administered orally to Nc\\/Nga mice, which led to the remarkable suppression of the development of dermatitis, as determined by

Yuba Raj Pokharel; Sung Chul Lim; Sang Chan Kim; Tae-Hwe Heo; Hoo Kyun Choi; Keon Wook Kang

2008-01-01

79

[The prevalence, prevention and treatment of cattle epidemic during the Han-Tang Period].  

PubMed

About 21 times of cattle epidemic with rather strong infectivity happened during the Han-Tang Period, including 6 in the Eastern Han Dynasty, 2 in the Jin Dynasty, 4 in the Southern and Northern Dynasties, 8 in the Tang Dynasty and 1in the Five Dynasty. Most of them were spread along the Yellow River and the northern region of the Huai River. The type of cattle epidemic included the acute cattle plague, cattle bovine mange, cattle yellow fever and cattle rotten hoof disease, etc. Its occurrence and prevalence brought a serious influentce on the society of the Han and Tang Dynasties, causing massive mortality of farm cattle, and then the shortage of animal power, and threatening the agriculture, which drew the attention of the governments, physicians, agriculturists, astrologists and Taoists. The medical measures and economic measures were adopted for the prevention and treatment of cattle epidemic. Especially, prescriptions in the books of medicine and agriculture exerted positive effects on the containment of cattle epidemic. On the other hand, its prevalence and the mass mortality of farm cattle, in a way, promoted, to certain extent, the improvement of the government's function of relief, the updating of the methods of agriculture and the creation of new farm tools, and being regarded as a main cause for the technological innovation of agriculture. PMID:24135474

Han, Yi

2013-03-01

80

Anti-herpes simplex virus effects of berberine from Coptidis rhizoma, a major component of a Chinese herbal medicine, Ching-Wei-San.  

PubMed

Berberine is an alkaloid extracted from Coptidis rhizome. Among the individual herbal components of a Chinese herb medicine, Ching-Wei-San, Coptidis Rhizoma has the most potent antimicrobial activity. By high-pressure liquid chromatography, the quantitative analysis of berberine from 6.25-mg/mL (w/v) Coptidis rhizome extract or 50.00-mg/mL (w/v) Ching-Wei-San was determined to be 0.26 mg/mL. To explore the potential use of Ching-Wei-San against herpes simplex virus (HSV) infection, the cytotoxicity, anti-HSV-1 and anti-HSV-2 activity in Vero cells were assayed. The selectivity index of berberine was about 1.2-1.5 times higher than that of Coptidis rhizome extract and Ching-Wei-San. Moreover, the antiviral activities correspond to the content of berberine in the aqueous solution. Berberine may interfere with the viral replication cycle after virus penetration and no later than the viral DNA synthesis step, and its activities were not affected by the preparation processes. Berberine, the natural plants that contain this component, including Coptidis rhizome, and Ching-Wei-San have all shown anti-HSV effects. PMID:20686799

Chin, Lengsu William; Cheng, Yu-Wen; Lin, Shih-Shen; Lai, Ya-Yun; Lin, Long-Yau; Chou, Ming-Yung; Chou, Ming-Chih; Yang, Chi-Chiang

2010-08-05

81

Our hero Wang can't be wrong! A case study of collectivistic image repair in Taiwan  

Microsoft Academic Search

Asian culture is often characterized as collectivist, as opposed to the individualism of Western culture. To extend the implications of collectivism, the current study applies the Theory of Image Restoration to analyze Taiwan's news reports of Taiwan-born Major League Baseball (MLB) pitcher Wang Chien-ming. Due to his outstanding performance in MLB, Wang has been styled by Taiwanese media as Taiwan

Wei-chun Wen; Tzu-hsiang Yu; William L. Benoit

2009-01-01

82

First description of the female of Sinopoda serrata (Wang, 1990) (Araneae, Sparassidae).  

PubMed

The female of Sinopoda serrata (Wang, 1990) is described for the first time from Tiantangzhai National Forest Park, Hubei province, China. This species has been recorded from the region of Central China. Morphological descriptions and illustrations of this species are given. PMID:23950691

Quan, Dan; Chen, Jian; Liu, Jie

2013-08-07

83

Improved Wang-Landau algorithm for the joint density of states of continuous models  

NASA Astrophysics Data System (ADS)

The joint density of states of a statistical physical system is the key to calculating thermodynamic observables at all temperatures and external fields. For example, ?(M, E) of a Heisenberg ferromagnet is a generalization of ?(E), from which magnetization and susceptibility at all temperatures can be obtained. A well-known method to calculate ?(E) is the Wang-Landau algorithm [1], which can be in principle extended to the joint density of states. Unfortunately, a straightforward application of the Wang-Landau algorithm to this type of problem turns out to be inefficient. We thus adopt a number of strategies to accelerate the simulation and to increase the performance of the algorithm in low-density regimes. In particular, we replace the conventional binning scheme with kernel density estimation, so that the algorithm is intrinsically suitable for continuous systems. This version of the Wang-Landau algorithm is also generally applicable to classical statistical physics models, including discrete models with large size. We also discuss other promising applications to magnetic nano-particles and in biophysics. [1] F. Wang and D. P. Landau, Phys. Rev. Lett. 86, 2050 (2001). *This research is supported by the Department of Energy through the Laboratory Technology Research Program of OASCR and the Computational Materials Science Network of BES under Contract No. DE-AC05-00OR22725 with UT-Battelle LLC, and by NSF DMR-0341874.

Zhou, Chenggang; Schulthess, T. C.

2005-03-01

84

Additional symbols used in double-spaced text for Wang OIS word-processor users  

SciTech Connect

This paper illustrates samples of Greek symbols (and other symbols) that are on the Wang daisy printwheel but not in the form that is often required. This technique can be used in place of rub-ons. It applies to double-spaced formats only, and involves creating new format lines within the text.

Miller, J.A.

1983-06-01

85

National identity, nation and race: Wang Jingwei's early revolutionary ideas, 1905–1911  

Microsoft Academic Search

This article examines Wang Jingwei's ideas on nation and race before the 1911 Revolution. It has often been agreed by scholars that there was a strong current of anti-Manchuism among the revolutionaries and as a result, on the eve of the 1911 Revolution, the revolutionaries remained divided as to whether the new Republic should inherit all the territories ruled by

So Wai Chor

2010-01-01

86

Discussion: 'Ovarian epithelial carcinoma with pelvic endometriosis,' by Wang et al.  

PubMed

In the roundtable that follows, clinicians discuss a study published in this issue of the Journal in light of its methodology, relevance to practice, and implications for future research. Article discussed: Wang S, Qui L, Lang JH, et al. Clinical analysis of ovarian epithelial carcinoma with coexisting pelvic endometriosis. PMID:23500450

Van Le, Linda; Jackson, Amanda; Schuler, Kevin; Suri, Anuj; Doll, Kemi; Stine, Jessica; Kim, Kenneth

2013-03-15

87

An L1-script-transfer-effect fallacy: a rejoinder to Wang et al. (2003)  

Microsoft Academic Search

Do different L1 (first language) writing systems differentially affect word identification in English as a second language (ESL)? Wang, Koda, and Perfetti [Cognition 87 (2003) 129] answered yes by examining Chinese students with a logographic L1 background and Korean students with an alphabetic L1 background for their phonological and orthographic processing skills on English word identification. Such a conclusion is

Jun Yamada

2004-01-01

88

Predicting Brand Purchase Behavior: A Marketing Application of the Schonemann-Wang Unfolding Model.  

National Technical Information Service (NTIS)

The purpose of the research is to examine the predictive power of the Schonemann-Wang (1972) joint space model that unfolds preference judgments. The model is fitted to scaled brand preferences derived from Pessemier's (1971) dollar metric graded paired p...

E. A. Pessemier W. Moore T. Little

1976-01-01

89

Additional symbols used in double-spaced text for Wang OIS word-processor users  

Microsoft Academic Search

This paper illustrates samples of Greek symbols (and other symbols) that are on the Wang daisy printwheel but not in the form that is often required. This technique can be used in place of rub-ons. It applies to double-spaced formats only, and involves creating new format lines within the text.

1983-01-01

90

Commentary: A Closer Look at Task Analysis--Reactions to Wang, Schnipke, and Witt  

ERIC Educational Resources Information Center

|In the Spring 2005 issue, Wang, Schnipke, and Witt provided an informative description of the task inventory approach that centered on four functions of job analysis. The discussion included persuasive arguments for making systematic connections between tasks and KSAs. But several other facets of the discussion were much less persuasive. This…

LaDuca, Tony

2006-01-01

91

Learning from Wang Yang-Ming: Exploring Oriental Contributions to Understanding Action Research  

ERIC Educational Resources Information Center

|This article reports recent foraging for ideas in action research among the lives and intellects of Chinese society. It began and is reported as a personal journey, initially following the trail of the activist scholar Wang Yang-Ming. The method is a roam through some of the resources that have so far been discovered. The style is…

Tickle, Les

2005-01-01

92

An L1-Script-Transfer-Effect Fallacy: A Rejoinder to Wang et al  

ERIC Educational Resources Information Center

|Do different L1 (first language) writing systems differentially affect word identification in English as a second language (ESL)? Wang, Koda, and Perfetti [Cognition 87 (2003) 129] answered yes by examining Chinese students with a logographic L1 background and Korean students with an alphabetic L1 background for their phonological and…

Yamada, Jun

2004-01-01

93

Indoor air exposure to coal and wood combustion emissions associated with a high lung cancer rate in Xuan Wei, China  

SciTech Connect

Residents of Xuan Wei County in China have unusually high lung cancer mortality that cannot be attributed to tobacco use or occupational exposure. They are exposed to smoke from unvented, open pit coal or wood fires (often used for cooking and heating). The variation in lung cancer rates among communes within the county suggests that indoor combustion of smoky coal may be the prime determinant of lung cancer. To characterize the air in Xuan Wei homes, samples of the air particles and semivolatile organic compounds were collected from homes located in two communes; one commune has a high rate of lung cancer, and the other has a low rate. Samples collected in the commune where the lung cancer rate is high and where smoky coal is the predominant fuel contained high concentrations of small particles with high organic content; organic extracts of these samples were mutagenic. Samples from homes in the wood-burning commune, which has a low rate of lung cancer, consisted mostly of larger particles of lower organic content and mutagenicity. The smoky coal sample was a mouse skin carcinogen and was a more potent initiator of skin tumors in comparison to the wood or smokeless coal sample.

Mumford, J.L.; Chapman, R.S.; Harris, D.B.; He, X.Z.; Cac, S.R.

1989-01-01

94

Indoor air exposure to coal and wood combustion emissions associated with a high lung cancer rate in Xuan Wei, China  

SciTech Connect

Residents of Xuan Wei County in China have unusually high lung cancer mortality that cannot be attributed to tobacco use or occupational exposure. They are exposed to smoke from unvented, open pit coal or wood fires (often used for cooking and heating). The variation in lung cancer rates among communes within the county suggests that indoor combustion of smoky coal may be the prime determinant of lung cancer. To characterize the air in Xuan Wei homes, samples of air particles and semivolatile organic compounds were collected from homes located in two communes; one commune has a high rate of lung cancer, and the other has a low rate. Samples collected in the commune where the lung cancer rate is high and where smoky coal is the predominant fuel contained high concentrations of small particles with high organic content; organic extracts of these samples were mutagenic. Samples from homes in the wood-burning commune, which has a low rate of lung cancer, consisted mostly of larger particles of lower organic content and mutagenicity. The smoky coal sample was a mouse skin carcinogen and was a more potent initiator of skin tumors in comparison to the wood or smokeless coal sample.

Mumford, J.L.; Chapman, R.S.; Harris, D.B. (Environmental Protection Agency, Research Triangle Park, NC (USA)); He, X.Z.; Cao, S.R.; Xian, Y.L.; Li, X.M. (Institute of Environmental Health and Engineering, Beijing (China))

1989-01-01

95

Spatial and temporal variations of nitrogen pollution in Wen-Rui Tang River watershed, Zhejiang, China.  

PubMed

Water quality has degraded dramatically in Wen-Rui Tang River watershed, Zhejiang, China, especially due to rapid economic development since 1995. This paper aims to assess spatial and temporal variations of the main pollutants (NH??-N, TN, BOD(5), COD(Mn), DO) of water quality in Wen-Rui Tang River watershed, using the geographic information system, cluster analysis (CA) and principal component analysis (PCA). Results showed that concentrations of BOD(5), COD(Mn), NH??-N, and TN were significantly higher in tertiary rivers than in primary and secondary rivers. From April 2006 to March 2007, the concentrations of NH? ?-N (2.25-57.9 mg/L) and TN (3.78-70.4 mg/L) in all samples exceeded Type V national water quality standards (?2 mg/L), while 5.3% of all COD(Mn) (1.83-27.5 mg/L) and 33.6% of all BOD(5) (0.34-50.4 mg/L) samples exceeded Type V national water quality standards (COD(Mn)?? 15 mg/L, BOD(5)?? 10 mg/L). Monthly changes of pollutant concentrations did not show a clear pattern, but correlation analysis indicated that NH??-N and TN in tertiary rivers had a significant negative correlation with 5-day cumulative rainfall and monthly rainfall, while there were no significant correlations in primary and secondary rivers. The results of CA and spatial analysis showed that the northern part of Wen-Rui Tang River watershed was the most seriously polluted. This region is characterized by the high population density and industrial and commercial activities. The PCA and spatial analysis indicated that the degraded water quality is caused by anthropogenic activities and poor wastewater management. PMID:21161588

Lu, Ping; Mei, Kun; Zhang, Yujin; Liao, Lingling; Long, Bibo; Dahlgren, Randy A; Zhang, Minghua

2010-12-15

96

Comment to ``Chlorine stable isotopes and halogen concentrations in convergent margins with implications for the Cl isotopes cycle in the ocean'' by Wei et al. A review of the Cl isotope composition of serpentinites and the global chlorine cycle  

Microsoft Academic Search

Wei et al. [Wei, W., Kastner, M., Spivack, A., 2008. Chlorine stable isotope and halogen concentrations in convergent margins with implications for the Cl isotopes cycle in the ocean. Earth Planet. Sci. Lett. 266, 90 104] published chlorine isotope data for pore fluids and serpentinites from three subduction zones and two obducted serpentinites. The measured delta37Cl values of serpentinites ranged

Z. D. Sharp; J. D. Barnes

2008-01-01

97

Utility of the Wang 18-gauge transbronchial histology needle in the staging of bronchogenic carcinoma.  

PubMed

Use of the Wang 18-gauge histology needle in TBNA was employed as a staging procedure in 29 patients with bronchogenic carcinoma and mediastinal adenopathy demonstrated on chest CT. Twenty patients had malignant aspirates; 12 had both histologic and cytologic specimens demonstrating malignancy; six patients had malignant histologic specimens; two had cancerous cytologic specimens as their only evidence of mediastinal disease. Of the nine negative aspirates, four were true negative at surgery. Five patients had false-negative aspirates. Overall sensitivity of the Wang 18-gauge histology needle in the mediastinal staging of patients with bronchogenic carcinoma was 80 percent. When patients with small cell carcinoma were excluded, sensitivity was 82 percent. The enhanced yield of the 18-gauge histology needle warrants its use in mediastinal staging of bronchogenic carcinoma. We conclude that all patients with bronchogenic carcinoma and mediastinal adenopathy demonstrated on chest CT accessible via TBNA should undergo histology needle aspiration as an initial staging procedure. PMID:2752809

Schenk, D A; Strollo, P J; Pickard, J S; Santiago, R M; Weber, C A; Jackson, C V; Burress, R S; Dew, J A; Komadina, K H; Segarra, J

1989-08-01

98

Coupling of the Wang Chang-Uhlenbeck equations with the multispecies Euler system  

NASA Astrophysics Data System (ADS)

After having recalled the basic properties of the Wang Chang-Uhlenbeck equations, we describe a class of relaxation schemes to solve the multispecies Euler system closed with a non-classical state equation, system which is the fluid limit of these kinetic equations. Then, we show how to couple the resolution of the Wang Chang-Uhlenbeck equations with the resolution of this Euler system by using a particular relaxation scheme - namely, a kinetic scheme - which allows to define a natural boundary condition at the kinetic-fluid interface and by using a Marshak condition to take into account the effect of the Knudsen layer in the fluid domain through an asymptotic matching. Finally, we show applications in the field of the Atomic Vapor Laser Isotopic Separation (AVLIS).

Dellacherie, Stéphane

2003-07-01

99

Unraveling the Beautiful Complexity of Simple Lattice Model Polymers and Proteins Using Wang-Landau Sampling  

Microsoft Academic Search

We describe a class of “bare bones” models of homopolymers which undergo coil-globule collapse and proteins which fold into\\u000a their native states in free space or into denatured states when captured by an attractive substrate as the temperature is\\u000a lowered. We then show how, with the use of a properly chosen trial move set, Wang-Landau Monte Carlo sampling can be

T. Wüst; Y. W. Li; D. P. Landau

100

Domesticating Chien-Ming Wang: A Comparative Study of the Media Coverage of Sports Performance  

Microsoft Academic Search

The purposes of this study are three-fold. The primary goal is to examine the narratives that two mainstream newspapers in Taiwan and America, Li-Tai Sports Newspaper (LT) and The New York Times (NYT), used when covering the performance of the athlete Chien-Ming Wang. The second purpose is to see how the presence of news frames varies in the two countries.

Hsing-Ju Chang

2009-01-01

101

GSTM1 AND GSTT1 GENOTYPES AND LUNG CANCER RISK ASSOCIATED WITH EXPOSURE TO INDOOR COAL EMISSIONS: A CASE-CONTROL STUDY IN XUAN WEI, CHINA  

EPA Science Inventory

The lung cancer mortality rate in Xuan Wei County, China is among the highest in the country and has been associated with exposure to indoor smoky coal emissions that contain high levels of polycyclic aromatic hydrocarbons. This risk may be modified by variation in metabolism gen...

102

DNA ADDUCTS AS BIOMARKERS FOR ASSESSING EXPOSURE TO POLYCYCLIC AROMATIC HYDROCARBONS IN TISSUES FROM XUAN WEI WOMEN WITH HIGH EXPOSURE TO COAL COMBUSTION  

EPA Science Inventory

The high lung cancer raze in Xuan Wei, China, is associated with smoky coal use in unvented homes. moky coal combustion emits higher levels of polycyclic aromatic hydrocarbons (PAH) than wood combustion. his study used DNA adducts as a biomarker for human exposure to PAH from com...

103

HUMAN EXPOSURE AND DOSIMETRY OF POLYCYCLIC AROMATIC HYDROCARBONS IN URINE FROM XUAN WEI, CHINA WITH HIGH LUNG CANCER MORTALITY ASSOCIATED WITH EXPOSURE TO UNVENTED COAL SMOKE  

EPA Science Inventory

Lung cancer mortality rate in Xuan Wei (XW) county, China is 5 times the China national average; women's rate is China's highest. W residents have been exposed to unvented coal or wood smoke during cooling or heating in homes. his study investigated indoor air exposure and dosime...

104

POLYMORPHISMS IN THE DNA BASE EXCISION REPAIR GENES APEX1 AND XRCC1 AND LUNG CANCER RISK IN XUAN WEI, CHINA  

EPA Science Inventory

The lung cancer mortality rate in Xuan Wei County is among the highest in China and has been attributed to exposure to indoor smoky coal emissions that contain very high levels of polycyclic aromatic hydrocarbons (PAHs). Nucleotide excision repair (NER) plays a key role in revers...

105

MOUSE SKIN TUMORIGENICITY STUDIES OF INDOOR COAL AND WOOD COMBUSTION EMISSIONS FROM HOMES OF RESIDENTS IN XUAN WEI, CHINA WITH HIGH LUNG CANCER MORTALITY  

EPA Science Inventory

The rural Xuan Wei County, Yunnan Province, China, has an unusually high lung cancer mortality rate that cannot be attributed to tobacco smoke or occupational exposure. he lung cancer rate is associated with "smoky" coal, in contrast to wood or "smokeless" coal burned in unventil...

106

Mouse skin tumorigenicity studies of indoor coal and wood combustion emissions from homes of residents in Xuan Wei, China with high lung cancer mortality  

Microsoft Academic Search

The rural Xuan Wei County, Yunnan Province, China, has an unusually high lung cancer mortality rate that cannot be attributed to tobacco smoke or occupational exposure. The lung cancer rate is associated with 'smoky' coal, in contrast to wood or 'smokeless' coal burned in unventilated homes. The study was conducted to characterize and compare mouse skin tumorigenicity of the coal

Judy L. Mumford; C. Tucker Helmes; Xueming Lee; Janice Seidenberg; Stephen Nesnow

1990-01-01

107

Highly parallel computational study of amphiphilic molecules using the Wang--Landau method  

NASA Astrophysics Data System (ADS)

The self-assembly process in amphiphilic solutions is a phenomenon of broad interest. Molecular dynamics simulations generally used to study micelle formation or lipid layer assembly in an explicit solvent are limited in time scale. Vast studies of structure formation processes via standard Markov-chain based Monte Carlo simulations are challenging, but the Wang--Landau method [1] provides a way to efficiently study such systems in a generalized thermodynamic ensemble. This makes it possible, for example, to get results over a broad temperature range from a single simulation. In an attempt to develop highly parallel applications using this method, we study the thermodynamic behavior of a generic coarse-grained model for amphiphilic molecules [2] as well as of a new coarse-grained lipid model specifically designed for dimyristoyl phosphatidylcholine (DMPC) [3]. Here, we focus on the design and the performance of our parallel Wang--Landau simulation on multi-CPU and GPU systems.[4pt] [1] F. Wang and D.P. Landau, Phys. Rev. Lett. 86, 2050 (2001)[0pt] [2] S. Fujiwara et al., J. Chem. Phys. 130, 144901 (2009)[0pt] [3] W. Shinoda et al., J. Phys. Chem. B 114, 6836 (2010)

Vogel, Thomas; Landau, David

2012-02-01

108

Optimality of Wang Landau sampling and performance limitations of flat histogram methods  

NASA Astrophysics Data System (ADS)

Wang-Landau sampling [F. Wang and D.P. Landau, PRL 86, 2050 (2001) ], an optimized and scalable flat-histogram sampling scheme, has been successfully used in the past two years to overcome tunneling problems at first order transitions and for systems with complex energy landscapes. While perfect scaling has been shown at first order transitions, the situation is less clear for spin glasses. We have determined the optimal scaling of local-update flat-histogram methods with system size by using a perfect flat-histogram scheme based on the exact density of states of the 2D Ising model and the 2D Ising spin glass, obtained using Saul and Kardar's algorithm. We demonstrate that the Wang-Landau algorithm shows the same scaling as the perfect scheme and is thus optimal. However, also for the perfect scheme the scaling with the number of spins N is not the minimal N^2 of an unbiased random walk in energy space, but slower, namely N^2+z, with z0.35 for the pure Ising model and even larger for the Ising spin glass.

Troyer, Matthias; Dayal, Prakash; Trebst, Simon; Sabhapandit, Sanjib; Coppersmith, Susan

2003-03-01

109

Potential ex vivo immunomodulatory effects of San-Huang-Xie-Xin-Tang and its component herbs on mice and humans  

Microsoft Academic Search

Aim of the studySan-Huang-Xie-Xin-Tang (SHXXT), an important Chinese medicine formula, contains Rhei Rhizoma (RR), Scutellariae Radix (SR) and Coptidis Rhizoma (CR). RR and SR are abundant in anthraquinone and flavonoid polyphenols. Pharmacokinetic study of SHXXT indicated that glucuronides were the predominant forms of polyphenols in rats.

Chia-Yang Li; Yu-Chi Hou; Pei-Dawn Lee Chao; Chi-Sheng Shia; Ian C. Hsu; Shih-Hua Fang

2010-01-01

110

Daeganghwal-tang inhibits the stem cell factor-induced migration and inflammatory cytokines secretion in mast cells  

Microsoft Academic Search

Traditional Oriental medicinal prescription, Daeganghwal-tang (DGHT) has been used for the treatment of rheumatoid arthritis (RA) in Korea. However, its effect in experimental models remains unknown. Recent reports suggest that in patients with RA, synovial mast cells increase in number and show signs of activation and inflammatory cytokines secretion. Our results show that stem cell factor (SCF) is a potent

H. Y Shin; H. J Jeong; H. J Na; S. H Hong; S. K Lee; K. N Lee; Y. S Song; H. M Kim; T. Y Shin

2003-01-01

111

Full-Scale Process and Design Changes for Elimination of Insulation Edge Separations and Voids in Tang Flap Area.  

National Technical Information Service (NTIS)

Qualification of the full-scale process and design changes for elimination of redesigned solid rocket motor tang nitrile butadiene rubber insulation edge separations and voids was performed from 24 March to 3 December 1990. The objectives of this test wer...

R. A. Danforth

1991-01-01

112

A Systems Biology-Based Investigation into the Pharmacological Mechanisms of Wu Tou Tang Acting on Rheumatoid Arthritis by Integrating Network Analysis  

PubMed Central

Aim. To investigate pharmacological mechanisms of Wu Tou Tang acting on rheumatoid arthritis (RA) by integrating network analysis at a system level. Methods and Results. Drug similarity search tool in Therapeutic Targets Database was used to screen 153 drugs with similar structures to compositive compounds of each ingredient in Wu Tou Tang and to identify 56 known targets of these similar drugs as predicted molecules which Wu Tou Tang affects. The recall, precision, accuracy, and F1-score, which were calculated to evaluate the performance of this method, were, respectively, 0.98, 0.61, 59.67%, and 0.76. Then, the predicted effector molecules of Wu Tou Tang were significantly enriched in neuroactive ligand-receptor interaction and calcium signaling pathway. Next, the importance of these predicted effector molecules was evaluated by analyzing their network topological features, such as degree, betweenness, and k-coreness. We further elucidated the biological significance of nine major candidate effector molecules of Wu Tou Tang for RA therapy and validated their associations with compositive compounds in Wu Tou Tang by the molecular docking simulation. Conclusion. Our data suggest the potential pharmacological mechanisms of Wu Tou Tang acting on RA by combining the strategies of systems biology and network pharmacology.

Zhang, Yanqiong; Lin, Na

2013-01-01

113

Use of Herbal Dietary Supplement Si-Wu-Tang and Health-Related Quality of Life in Postpartum Women: A Population-Based Correlational Study  

PubMed Central

Objective. The aim of the study was to explore the association between women's use of herbal dietary supplement Si-Wu-Tang during the postpartum period and their health-related quality of life. Methods. This is a population-based correlational study. We used multistage, stratified, systematic sampling to recruit 24,200 pairs of postpartum women and newborns from the Taiwan National Birth Registry in 2005. A structured questionnaire was successfully administered to 87.8% of the sampled population. Trained interviewers performed home interviews 6 months after the women's deliveries between June 2005 and July 2006. The Medical Outcomes Study 36-item Short-Form (SF-36) was used to measure the quality of life of the women along with the frequency of Si-Wu-Tang use. Results. Si-Wu-Tang use after delivery improved women's score for bodily pain and also improved their score for mental health when used more than 10 times. In addition, there were increases in general health and vitality scores in the group who continuously used Si-Wu-Tang more than 10 times after using Sheng-Hua-Tang. Conclusion. Use of Si-Wu-Tang after delivery may be associated with women's health-related quality of life especially for those who previously used Sheng-Hua-Tang. These results are exploratory and need to be replicated.

Chang, Pei-Jen; Lin, Ching-Chun; Chen, Yi Chun; Chuang, Chao-Hua; Tseng, Yu-Ching; Hsieh, Wu-Shiun; Lin, Shio-Jean

2013-01-01

114

Improved methods for calculating thermodynamic properties of magnetic systems using Wang-Landau density of states  

SciTech Connect

The Wang-Landau method [F. Wang and D. P. Landau, Phys. Rev. E 64, 056101 (2001)] is an efficient way to calculate the density of states (DOS) for magnetic systems, and the DOS can then be used to rapidly calculate the thermodynamic properties of the system. A technique is presented that uses the DOS for a simple Hamiltonian to create a stratified sample of configurations which are then used calculate a warped DOS for more realistic Hamiltonians. This technique is validated for classical models of bcc Fe with exchange interactions of increasing range, but its real value is using the DOS for a model Hamiltonian calculated on a workstation to select the stratified set of configurations whose energies can then be calculated for a density-functional Hamiltonian. The result is an efficient first-principles calculation of thermodynamic properties such as the specific heat and magnetic susceptibility. Another technique uses the sample configurations to calculate the parameters of a model exchange interaction using a least-squares approach. The thermodynamic properties can be subsequently evaluated using traditional Monte Carlo techniques for the model exchange interaction. Finally, a technique that uses the configurations to train a neural network to estimate the configuration energy is also discussed. This technique could potentially be useful in identifying the configurations most important in calculating the warped DOS. VC2011 American Institute of Physics. [doi:10.1063/1.3565413

Brown, Greg [ORNL; Rusanu, Aurelian [ORNL; Daene, Markus W [ORNL; Nicholson, Don M [ORNL; Eisenbach, Markus [ORNL; Fidler, Jane L [ORNL

2011-01-01

115

Simultaneous determination of 12 chemical constituents in the traditional Chinese Medicinal Prescription Xiao-Yao-San-Jia-Wei by HPLC coupled with photodiode array detection  

Microsoft Academic Search

An HPLC-photodiode array (PDA) detection method was established for the simultaneous determination of 12 components in Xiao-Yao-San-Jia-Wei (XYSJW): geniposide, puerarin, paeoniflorin, ferulic acid, liquiritin, hesperidin, naringin, paeonol, daidzein, glycyrrhizic acid, honokiol, and magnolol. These were separated in less than 70min using a Waters Symmetry Shield RP 18 column with gradient elution using (A) acetonitrile, (B) water, and (C) acetic acid

Hongmin Zhang; Shiwei Chen; Feng Qin; Xi Huang; Ping Ren; Xinqi Gu

2008-01-01

116

Effect of chimneys on indoor air concentrations of PM 10 and benzo[a]pyrene in Xuan Wei, China  

NASA Astrophysics Data System (ADS)

This paper reports the effect of chimneys in reducing indoor air pollution in a lung cancer epidemic area of rural China. Household indoor air pollution concentrations were measured during unvented burning (chimneys blocked) and vented burning (chimneys open) of bituminous coal in Xuan Wei, China. Concentrations of particulate matter with an aerodynamic diameter of 10 ?m or less (PM 10) and of benzo[a]pyrene (BaP) were measured in 43 homes during normal activities. The use of chimneys led to significant decreases in indoor air concentrations of particulate matter with an aerodynamic diameter of 10 ?m or less (PM 10) by 66% and of benzo[a]pyrene (BaP) by 84%. The average BaP content of PM 10 also decreased by 55% with the installation of a chimney. The reduction of indoor pollution levels by the installation of a chimney supports the epidemiology findings on the health benefits of stove improvement. However, even in the presence of a chimney, the indoor air concentrations for both PM 10 and BaP still exceeded the indoor air quality standards of China. Movement up the energy ladder to cleaner liquid or gaseous fuels is probably the only sustainable indoor air pollution control measure.

Tian, Linwei; Lan, Qing; Yang, Dong; He, Xingzhou; Yu, Ignatius T. S.; Hammond, S. Katharine

117

Effects of age, size, and density on natural survival for an important coral reef fishery species, yellow tang, Zebrasoma flavescens  

Microsoft Academic Search

Hundreds of thousands of juvenile yellow tang, Zebrasoma flavescens, are caught each year in the state of Hawai’i (USA) for the live aquarium trade. As part of an extensive adaptive management\\u000a strategy built around a network of protected areas, an emphasis was placed on understanding this important species’ life history.\\u000a Multiple capture-mark-recapture techniques and a model selection approach to data

J. T. Claisse; S. A. McTee; J. D. Parrish

2009-01-01

118

Tang-Song or Song-Ming: The Significance of a Perspective Shift in Chinese Cultural and Intellectual History  

Microsoft Academic Search

Discussions on the contrast between the Tang and Song dynasties are common in Chinese cultural and intellectual history. Will\\u000a it make more sense if the continuity between Song and Ming are emphasized instead? This shift in research perspective will\\u000a have multiple effects. Instead of paying exclusive attention to the elites and classics, we will focus on common knowledge,\\u000a thoughts, and

Zhaoguang Ge

2006-01-01

119

Anti-inflammatory effect of So-Pung-Tang, a Korean traditional prescription for cerebral infarction patients  

Microsoft Academic Search

So-Pung-Tang (Sopung), a prescription composed of 14 herbal mixtures, has been widely used in the treatment of cerebral infarction in Oriental Medicine. However, the mechanisms by which the formula affects on the production of pro-inflammatory cytokines in cerebral infarction patients remain unknown yet. The levels of secretory protein of pro-inflammatory cytokines, including tumor necrosis factor (TNF)-?, interlukin (IL)-1?, and IL-6,

Yunha Kim; Hong-Seob So; Myung-Ja Youn; Eun Sook Kim; Mi-Sun Song; Kyu Yun Chai; Won-Hong Woo; Kwang-Ho Cho; Byung-Soon Moon

2007-01-01

120

Vasorelaxation by Samhwangsasim-tang, an herb medicine, is associated with decreased phosphorylation of the myosin phosphatase target subunit  

Microsoft Academic Search

Samhwangsasim-tang (SST) is a widely used herbal medicine with vasodilatory actions in oriental countries. We hypothesized that SST modulates vascular contractility by decreasing phosphorylation of the myosin phosphatase target subunit.Rat aortic ring preparations were mounted in organ baths and subjected to contractions or relaxations. Phosphorylation of 20kDa myosin light chains (MLC20) and MYPT1, a target subunit of myosin phosphate 1,

Fanxue Jin; Heung-Mook Shin; Su Bun Jeon; Inji Baek; En-yue Yang; Jee In Kim; Young Mi Seok; Young-Ho Lee; In Kyeom Kim

2007-01-01

121

Simultaneous determination of eight marker compounds in the traditional herbal medicine, Sipjundaebo-tang by HPLC-DAD.  

PubMed

Sipjundaebo-tang, known as a traditional herbal medicine, has been used in the treatment of anemia, inflammation, and tumor. For simultaneous determination of eight components, namely 5-HMF, paeoniflorin, ferulic acid, cinnamaldehyde, decursinol, 6-gingerol, decursin, and glycyrrhizin in Sipjundaebo-tang, a high performance liquid chromatography-diode array detector (HPLC-DAD) method was established. In order to develop and validate this HPLC-DAD method, C(18) column (S-5 ?m, 4.6 × 250 mm) was used with gradient mobile phase at the column temperature of 35°C. The mobile phase was consisted of water and methanol containing 0.1% trifluoroacetic acid. UV wavelength was set at 230, 254, 280, and 300 nm. Validation of the analytical method was evaluated by linearity, precision, and accuracy test. Calibration curve for eight marker compounds showed good linearity with R(2) > 0.9994. Limits of detection and Limits of quantification ranged from 0.01 ?g/mL to 0.13 ?g/mL and 0.03 ?g/mL to 0.41 ?g/mL, respectively. The relative standard deviations (RSDs) value of precision test, intra-day and inter-day test, was less than 1.14% and 2.54%, respectively. The results of accuracy test were varied from 98.31% to 104.88% with RSD < 2%. This developed simultaneous determination method was efficient to the quality control of Sipjundaebo-tang. PMID:21975812

Yang, Hye Jin; Ma, Jin Yeul; Weon, Jin Bae; Ma, Choong Je

2011-10-06

122

Evaluation of Oral Subchronic Toxicity of Soshiho-Tang Water Extract: The Traditional Herbal Formula in Rats  

PubMed Central

Soshiho-tang (Xiao-chai-hu-tang in Chinese and Sho-saiko-to in Japanese) has been widely used for its various pharmacological effects, which include anti-inflammatory, antioxidant, antihepatic fibrosis, and antitumor properties. To evaluate the safety of Soshiho-tang water extract (SST), we tested its subchronic toxicity in male and female Crl:CD (SD) rats. Rats were orally treated with four different doses (0, 500, 1000, and 2000?mg/kg/day) of SST administered for 13 weeks. Mortality, clinical signs, body weight changes, food and water consumption changes, ophthalmology, urinalysis, hematological and biochemical parameters, gross findings, organ weights, and histological markers were monitored during the study. The SST treatment did not result in any toxicologically significant changes in mortality, clinical signs, body weights, food and water consumption, ophthalmoscopy, urinalysis, hematological and serum biochemical parameters, gross findings, organ weights, or histopathology. Histological analysis did not show any liver or kidney alteration. We concluded that the 13-week repeated oral administration of SST did not cause any adverse effects in rats at dosage levels of ?2000?mg/kg/day. Under these experimental conditions, the no-observed-adverse-effect level was concluded to be 2000?mg/kg/day for both sexes.

Lee, Mee-Young; Seo, Chang-Seob; Shin, In-Shik; Kim, Young-Bum; Kim, Jung-Hoon; Shin, Hyeun-Kyoo

2013-01-01

123

The Chinese Herbal Decoction Danggui Buxue Tang Inhibits Angiogenesis in a Rat Model of Liver Fibrosis  

PubMed Central

In this study, we investigated the anti-angiogenic effect of the Chinese herbal decoction Danggui Buxue Tang (DBT; Radix Astragali and Radix Angelicae sinensis in 5?:?1 ratio) in a rat model of liver fibrosis, in order to elucidate its mechanisms of action against liver fibrosis. Liver fibrosis was induced with CCl4 and high-fat food for 6 weeks, and the rats were treated with oral doses of DBT (6?g raw herbs/kg/d) and N-Acetyl-L-cysteine (NAC; 0.1?g/kg/d). The results showed that both DBT and NAC attenuated liver fibrosis and neo-angiogenesis. Furthermore, DBT and NAC improved SOD activity but decreased MDA content and 8-OH-dG in fibrotic livers, with DBT being more effective than NAC. DBT decreased the expression of VEGF, Ang1 and TGF-?1 and their signaling mediators, whereas NAC had no effect on VEGF and VEGFR2 expression. Both DBT and NAC reduced HIF-1? gene and protein expression in fibrotic livers, with DBT being more effective. These data clearly demonstrate that the anti-fibrotic properties of DBT are related to its ability to inhibit angiogenesis and its anti-angiogenic mechanisms are associated with improving oxidative stress, regulating the expression and signaling of angiogenic factors, and especially modulating HIF-1? in fibrotic livers.

Lv, Jing; Zhao, Zhimin; Chen, Yuan; Wang, Qinglan; Tao, Yanyan; Yang, Li; Fan, Tai-Ping; Liu, Chenghai

2012-01-01

124

Simultaneous Determination of Seven Constituents in Herbal Prescription Jaeumganghwa-Tang Using HPLC-PDA.  

PubMed

A simple and accurate high-performance liquid chromatographic method was applied to the quantitative analysis of seven components of the traditional herbal prescription Jaeumganghwa-tang (JGT), including 5-hydroxymethyl-2-furaldehyde, albiflorin, paeoniflorin, liquiritin, ferulic acid, nodakenin, and glycyrrhizin. All seven compounds were separated in less than 40 min on a Gemini C18 column at 40°C by gradient elution using 1.0% (v/v) aqueous acetic acid and acetonitrile containing 1.0% (v/v) acetic acid as mobile phase. The flow rate was 1.0 mL/min and the detector was a photodiode array (PDA) set at 230 nm, 254 nm, 280 nm, and 330 nm. The calibration curves showed good linearity (r (2) > 0.9998) in different concentration ranges. The recovery of each component was in the range of 91.47-102.62%, with relative standard deviations (RSDs, %) less than 4.5%. The RSDs (%) for intra- and interday precision were 0.06-2.85% and 0.06-2.83%, respectively. The concentrations of the seven components in JGT were in the range 0.74-5.48 mg/g. PMID:24082332

Seo, Chang-Seob; Kim, Jung Hoon; Shin, Hyeun-Kyoo

2012-10-01

125

Effects of Berberine and Hwangryunhaedok-Tang on Oral Bioavailability and Pharmacokinetics of Ciprofloxacin in Rats  

PubMed Central

Hwangryunhaedok-Tang (HR) and berberine-containing single herbs are used to treat bacterial infection and inflammatory diseases in eastern Asia. The combination of berberine-containing herbal medicines and ciprofloxacin can be an excellent antibacterial chemotherapy against multidrug resistance bacteria. To evaluate the pretreatment effect of berberine and HR, vehicle, berberine (25 and 50?mg/kg/day), and HR (1.4?g/kg/day) were daily administered to rats for five consecutive days. On day 6, ciprofloxacin was administered (10?mg/kg, i.v. and 20?mg/kg, p.o.) to rats. To assess cotreatment effect of berberine and ciprofloxacin, berberine (50?mg/kg) and ciprofloxacin (20?mg/kg) were coadministered by single oral gavage. Pharmacokinetic data were estimated by noncompartmental model. Compared with ciprofloxacin alone (control group), coadministration of berberine (50?mg/kg) and ciprofloxacin significantly decreased Cmax of ciprofloxacin (P < 0.05). In addition, the pretreatment of berberine (50?mg/kg/day) and HR (1.4?g/kg/day) significantly decreased Cmax and AUC0??, compared with control group (P < 0.05). The oral bioavailability of ciprofloxacin was reduced by cotreatment of berberine and pretreatment of berberine and HR. Our results suggest that the expression of P-glycoprotein and organic anion and/or organic cation transporters (OAT/OCT) could take a role in reduced oral bioavailability of ciprofloxacin by berberine and HR.

Hwang, Youn-Hwan; Cho, Won-Kyung; Jang, Doorye; Ha, Jeong-Ho; Jung, Kiyoun; Yun, Hyo-In; Ma, Jin Yeul

2012-01-01

126

Sopungyangjae-Tang Inhibits Development of Dermatitis in Nc/Nga Mice  

PubMed Central

Sopungyangjae-Tang (SYT) is a traditional Korean decoction used for the treatment of dermatitis. The aim of this study was to confirm whether or not SYT has a preventive effect on the development of atopic dermatitis in dinitrochlorobenzene-applied Nc/Nga mice. SYT was administered orally to Nc/Nga mice, which led to the remarkable suppression of the development of dermatitis, as determined by a histological examination and the serum IgE levels. Moreover, SYT inhibited the production of thymus- and activation-regulated chemokine (TARC) and its mRNA expression in a keratinocyte cell line, HaCaT, which had been stimulated with tumor necrosis factor-? (TNF-?) and interferon-? (IFN-?). Activation of the nuclear factor-?B (NF-?B) or activator protein-1 (AP-1) is one of the key steps in the signaling pathways mediating induction of TARC. In this study, SYT selectively suppressed NF-?B activation, which may be essential for TARC expression in TNF-?/IFN-? treated keratinocytes. The inhibitory effect of SYT on NF-?B activation and TARC production might be associated with the anti-dermatitic effects of SYT.

Lim, Sung Chul; Kim, Sang Chan; Heo, Tae-Hwe; Choi, Hoo Kyun

2008-01-01

127

Thermodynamics and structural properties of a confined HP protein determined by Wang-Landau simulation  

SciTech Connect

We used Wang-Landau sampling with inventive Monte Carlo moves to study the influence of surface characteristics on physical behavior of a hydrophobic-polar (HP) lattice protein model confined between two attractive surfaces. Three types of surfaces, namely, surfaces that attract: (a) all monomers; (b) only P monomers; or (c) only H monomers, have been considered. After obtaining the densities of states, we then found the thermodynamic and structural quantities, such as specific heat, number of surface contacts, and number of hydrophobic interaction pairs. A few conformational transitions , e.g., debridging process and hydrophobic core formation, can be identified based on an analysis of these quantities. Depending on the surface types, these transitions take place at different temperatures, while the ground state configurations show structural variations. These scenarios are confirmed by snapshots of typical states of the systems.

Pattanasiri, Busara [Mahidol University, Bangkok 10400, Thailand; Li, Ying Wai [ORNL; Landau, David P [University of Georgia, Athens, GA; Wuest, Thomas [Swiss Federal Research Institute, Switzerland; Triampo, Wannapong [Mahidol University, Bangkok 10400, Thailand

2013-01-01

128

Numerical solutions of Wang's stretching/shrinking sheet problem for nanofluids  

NASA Astrophysics Data System (ADS)

The steady stagnation-point flow of a viscous and incompressible fluid over a continuously stretching or shrinking sheet in its own plane in a water-based copper (Cu) nanofluid is studied theoretically. The formulation of the present problem in a nanofluid follows that of Wang's stretching/shrinking sheet problem in a viscous fluid. The nonlinear partial differential equations are transformed into ordinary differential equations via the similarity transformation. The transformed boundary layer equations are solved numerically using the shooting method. The numerical solutions are obtained and discussed for the skin friction coefficient and the velocity profiles for various values of the governing parameters, namely the nanoparticle volume fraction and stretching/shrinking parameters. It is found that dual solutions exist for the shrinking sheet case.

Ali, Fadzilah Md; Nazar, Roslinda; Arifin, Norihan Md; Pop, Ioan

2013-09-01

129

Protective effect of Zhen-Wu-Tang ( ZWT) through keeping DA stable and VMAT 2\\/DAT mRNA in balance in rats with striatal lesions induced by MPTP  

Microsoft Academic Search

Ethnopharmacological relevanceZhen-Wu-Tang (ZWT), the modified formulation of a classical Chinese prescription from “Treaties on Febrile Disease”, was clinically employed to treat Parkinson's disease.

Xiu-Min Li; Chang-Liang Xu; Ji-Min Deng; Lu-Fan Li; Shi-Ping Ma; Rong Qu

2011-01-01

130

Why Three Heads Are a Better Bet than Four: A Reply to Sun, Tweney, and Wang (2010)  

ERIC Educational Resources Information Center

|We (Hahn & Warren, 2009) recently proposed a new account of the systematic errors and biases that appear to be present in people's perception of randomly generated events. In a comment on that article, Sun, Tweney, and Wang (2010) critiqued our treatment of the gambler's fallacy. We had argued that this fallacy was less gross an error than it…

Hahn, Ulrike; Warren, Paul A.

2010-01-01

131

Victimization in Korean Schools: The Nature, Incidence, and Distinctive Features of Korean Bullying or "Wang-Ta"  

ERIC Educational Resources Information Center

|School bullying in South Korea may take different forms from bullying in western societies, and there is little data on its nature and extent nationally. We report results from a nationwide survey on the Korean form of bullying, "wang-ta". Two pilot studies were carried out, to adapt a western-based questionnaire for use in Korea. With the…

Koo, Hyojin; Kwak, Keumjoo; Smith, Peter K.

2008-01-01

132

A new species and new records of the leafhopper genus Taperus Li & Wang, 1994 (Hemiptera,Cicadellidae, Evacanthinae) from China  

PubMed Central

Abstract The paper deals with the species of the Oriental leafhopper genus Taperus Li & Wang. A new species, Taperus daozhenensis sp. n., from Guizhou Province, China is described and new records for other Chinese species are given together with a key for their separation. The type specimens of the new species are deposited in the Institute of Entomology, Guizhou University (GUGC).

Li, Yu-jian; Li, Zi-zhong

2011-01-01

133

Hwangryun-Haedok-Tang Fermented with Lactobacillus casei Suppresses Ovariectomy-Induced Bone Loss  

PubMed Central

Hwangryun-haedok-tang (HRT) is the common recipe in traditional Asian medicine, and microbial fermentation is used for the conventional methods for processing traditional medicine. We investigated the inhibitory effect of the n-butanol fraction of HRT (HRT-BU) and fHRT (fHRT-BU) on the RANKL-induced osteoclastogenesis in bone-marrow-derived macrophages. mRNA expression of osteoclastogenesis-related genes were evaluated by real-time QPCR. The activation of signaling pathways was determined by western blot analysis. The marker compounds of HRT-BU and fHRT-BU were analyzed by HPLC. The inhibitory effect of HRT or fHRT on ovariectomy-induced bone loss were evaluated using OVX rats with orally administered HRT, fHRT (300, 1000?mg/kg), or its vehicle for 12 weeks. fHRT-BU significantly inhibited RANKL-induced osteoclastogenesis, and phosphorylation of p38, IKK?/?, and NF-?Bp65 compared to HRT-BU. In addition, fHRT-BU also significantly inhibited the mRNA expression of Nf?b2, TNF-?, NFATc1, TRAP, ATPv0d2, and cathepsin K. Furthermore, administration of fHRT had a greater effect on the increase of BMD, and greater improved bone microstructure of the femora than that of HRT in ovariectomy rats. This study demonstrated that bacterial fermentation enhances the inhibitory effect of HRT on osteoclastogenesis and bone loss. These results suggest that fermented HRT might have the beneficial effects on bone disease by inhibiting osteoclastogenesis.

Shim, Ki-Shuk; Kim, Taesoo; Ha, Hyunil; Cho, Chang-Won; Kim, Han Sung; Seo, Dong-Hyun; Ma, Jin Yeul

2012-01-01

134

Cytochrome P450-mediated herb-drug interaction potential of Galgeun-tang.  

PubMed

We evaluated the herb-drug interaction potential of Galgeun-tang (GGT) extracts, mediated by cytochrome P450 (CYP) inhibition/induction. Further, the effects of fermentation on the CYP-mediated herb-drug interaction potential of GGT extracts were determined. As measured by LC-ESI/MS/MS, GGT extracts (0-300?g/mL) showed no inhibitory activity toward eight CYP isoforms (1A2, 2A6, 2B6, 2C9, 2C19, 2D6, 2E1, and 3A4) in pooled human liver microsomes, suggesting that GGT may have low potential for herb-drug interactions mediated by CYP inhibition. Hepatic CYP expression and activity in rats treated with GGT extracts twice per day for 1week was examined. Among the tested CYP isoforms (1A1, 1A2, 1B1, 2B1, 2C11, 2E1, 3A1, 3A2, and 4A1), CYP1B1 and 4A1 were increased by GGT extracts. Hepatic activities of 7-ethoxyresorufin-O-deethylase, 7-pentoxyresorufin-O-depentylase, and chlorzoxazone 6-hydroxylase, but not midazolam hydroxylase were also elevated. These results raise the possibility that GGT extracts may increase the toxicity of environmental toxicants through the elevating CYP-dependent metabolic activation. Interestingly, the increases in CYP1B1 and CYP4A1 levels, and 7-ethoxyresorufin-O-deethylase, 7-pentoxyresorufin-O-depentylase, and chlorzoxazone 6-hydroxylase activities were attenuated by fermentation of GGT extract using Lactobacillus plantarum KFRI 402, but not 144. Further studies are needed to identify the CYP regulatory component(s) from GGT and determination its metabolism. PMID:23104244

Lee, Sang Yoon; Lee, Ji-Yoon; Kang, Wonku; Kwon, Kwang-Il; Park, Song-Kyu; Oh, Soo Jin; Ma, Jin Yeul; Kim, Sang Kyum

2012-10-25

135

The molecular mechanisms of Yang Wei Kang Liu powder on anticancer and reducing chemotherapy side-effect in combination with chemotherapy  

Microsoft Academic Search

Objective  We studied the molecular mechanisms of Yang Wei Kang Liu Power (YWKL, traditional Chinese medicine for nourishing stomach\\u000a and anticancer) on anticancer and reducing chemotherapy side-effect in combination with chemotherapy.\\u000a \\u000a \\u000a \\u000a \\u000a Methods  615 pre-cancer mouse model of YWKL for 10 days and CTX 1 time, semi-quantitative reverse transcription-polymerase chain reaction\\u000a (RT-PCR) to detect bone marrow granulocyte-macrophage colony-stimulating factor (GM-CSF) gene and cancer

Guizhi Sun; Zhikui Wu; Jinyu Lu; Wenping Lu; Xun Wang

2010-01-01

136

An in vitro study of the antioxidant activities and effect on human DNA of the Chinese herbal decoction 'Liu Wei Di Huang'.  

PubMed

A Chinese medicinal formulation, 'Liu Wei Di Huang', and its individual components have been tested for the genoprotective effect on human DNA by the comet assay. Results showed no DNA protection contributed by this prescription. However, the aqueous extracts of individual herbs, namely Cortex Moutan and Rhizoma Dioscoreae, were able to decrease by 10-15% the DNA stand break from hydrogen peroxide-mediated oxidative stress. This provides insight to further evaluate the interaction among herbs and the search for the active ingredient responsible for the DNA protective effect. PMID:19919513

Szeto, Yim-Tong; Lei, Pui-Cheong; Ngai, Kam-Leong; Yiu, Andy Tak-Wah; Chan, Catarina Sin-Pek; Kok, Edith Wun-Fong; Leong, Chi-Wa

2009-12-01

137

Interoccurrence times in the Bak-Tang-Wiesenfeld sandpile model: a comparison with the observed statistics of solar flares.  

PubMed

A sequence of bursts observed in an intermittent time series may be caused by a single avalanche, even though these bursts appear as distinct events when noise and/or instrument resolution impose a detection threshold. In the Bak-Tang-Wiesenfeld sandpile, the statistics of quiet times between bursts switches from Poissonian to scale invariant on raising the threshold for detecting instantaneous activity, since each zero-threshold avalanche breaks into a hierarchy of correlated bursts. Calibrating the model with the time resolution of GOES data, qualitative agreement with the interoccurrence time statistics of solar flares at different intensity thresholds is found. PMID:16383890

Paczuski, Maya; Boettcher, Stefan; Baiesi, Marco

2005-10-27

138

Thermodynamics and structural properties of a confined HP protein determined by Wang-Landau simulation  

NASA Astrophysics Data System (ADS)

Understanding protein folding confined by surfaces is important for both biological sciences and the development of nanomaterials. In this work, we study the properties of a confined HP model protein by three different types of surfaces, namely, surfaces that attract: (a) all monomers; (b) only P monomers; and (c) only H monomers. The thermodynamic and structural quantities, such as the specific heat, number of surface contacts, and number of hydrophobic pairs, are obtained by using Wang-Landau sampling. The conformational "transitions", specifically, the debridging process and hydrophobic core formation, can be identified based on an analysis of these quantities. We found that these transitions take place at different temperatures, and the ground state configurations show variations in structural properties when different surface type is used. These scenarios are confirmed by snapshots of typical states of the systems. From our study, we conclude that the thermodynamics of these transitions and the structural changes depend on the combined actions of both the composition of the H monomers and the P monomers in the HP chain and the surface types.

Pattanasiri, Busara; Li, Ying Wai; Landau, David P.; Wüst, Thomas; Triampo, Wannapong

2013-08-01

139

Generic transition hierarchies of lattice HP protein adsorption: A Wang-Landau study  

NASA Astrophysics Data System (ADS)

We have applied Wang-Landau sampling with appropriate trial movesootnotetextT. W"ust and D. P. Landau, Phy. Rev. Lett. 102, 178101 (2009). to investigate the thermodynamics and structural properties of the HP lattice protein modelootnotetextK. A. Dill, Biochemistry 24, 1501 (1985). interacting with an attractive substrate. The conformational ``phase transitions'' of several benchmark HP sequences have been identified by a comprehensive canonical analysis of the specific heat and structural observables, e. g. radius of gyration and thermal derivatives of number of surface contacts. Three major ``transitions'': adsorption, hydrophobic core formation, and ``flattening'' of adsorbed structures, are observed. Depending on the surface attractive strength relative to the intra-protein attraction among the H monomers, these processes take place in a different order upon cooling. We identify a small number of generic categories that are sufficient to classify the folding hierarchies for different HP chains consisting of assorted sequences and chain lengths, regardless of the monomer type that the surface attracts. We thus believe that this classification scheme is generally applicable to lattice protein adsorption problems.

Li, Ying Wai; Landau, D. P.; Wüst, T.

2012-02-01

140

Micro-Raman analysis of the pigments on painted pottery figurines from two tombs of the Northern Wei Dynasty in Luoyang  

NASA Astrophysics Data System (ADS)

The pigments on the painted pottery figurines from two tombs of Northern Wei Dynasty (AD 386-534) in Luoyang were analyzed by Raman microscopy. All the pigments were identified compared with the Raman spectra of standard pigments. The red pigments were identified as haematite, the blue pigment as lapis lazuli, the green pigment as malachite, the black pigment as carbon black and the white pigment as calcite. Similar pigments were used in the two tombs despite the pottery figurines were very different in artistic style. The use of lapis lazuli as blue pigment on Chinese painted pottery figurines was found for the first time. This pigment and the painted pottery figurine of Sogdians are of great archaeological significance because it demonstrated that the trade and cultural exchanges via the Silk Road had extended to Luoyang city in the Northern Wei Dynasty. The result also confirms that micro-Raman spectroscopy is a powerful analytical method for the identification of pigments on ancient artworks.

Liu, Zhaojun; Han, Yunxia; Han, Ligang; Cheng, Yongjian; Ma, Yiqiang; Fang, Li

2013-05-01

141

Micro-Raman analysis of the pigments on painted pottery figurines from two tombs of the Northern Wei Dynasty in Luoyang.  

PubMed

The pigments on the painted pottery figurines from two tombs of Northern Wei Dynasty (AD 386-534) in Luoyang were analyzed by Raman microscopy. All the pigments were identified compared with the Raman spectra of standard pigments. The red pigments were identified as haematite, the blue pigment as lapis lazuli, the green pigment as malachite, the black pigment as carbon black and the white pigment as calcite. Similar pigments were used in the two tombs despite the pottery figurines were very different in artistic style. The use of lapis lazuli as blue pigment on Chinese painted pottery figurines was found for the first time. This pigment and the painted pottery figurine of Sogdians are of great archaeological significance because it demonstrated that the trade and cultural exchanges via the Silk Road had extended to Luoyang city in the Northern Wei Dynasty. The result also confirms that micro-Raman spectroscopy is a powerful analytical method for the identification of pigments on ancient artworks. PMID:23501716

Liu, Zhaojun; Han, Yunxia; Han, Ligang; Cheng, Yongjian; Ma, Yiqiang; Fang, Li

2013-02-21

142

Comment on “Estimation of potential distribution of gas hydrate in the northern South China Sea” by Chunjuan Wang et al  

Microsoft Academic Search

Herein we would like to comment on the paper “Estimation of potential distribution of gas hydrate in the northern South China\\u000a Sea” by Wang et al. 2010 in Chinese Journal of Oceanology and Limnology, 28(3): 693–699. The purpose of this comment is to point out that the given probabilities of gas hydrate occurrence in the\\u000a northern Zhujiang Mouth Basin and

Yi Zhang

2011-01-01

143

The WEI6K, a 6-kW 7-m Small Wind Turbine: Final Technical Report  

SciTech Connect

This project was selected by the U.S. Department of Energy under a DOE solicitation “Low Wind Speed Technology for Small Turbine Development.” The objective of this project has been to design a new small wind turbine with improved cost, reliability and performance in grid-connected residential and small business applications, in order to achieve the overall DOE goal of cost effectiveness in Class 3 wind resources that can now be achieved in Class 5 resources. The scope of work for this project has been to complete the preliminary design of an improved small wind turbine, including preliminary loads and strength analyses; analysis and design of all major components; systems integration and structural dynamic analysis; estimation of life-cycle cost of energy; and design documentation and review. The project did not entail hardware fabrication or testing. The WEI6K Turbine resulting from this project is an upwind horizontal-axis wind turbine rated at 6 kW. It features a 3-blade 7-m diameter rotor. The generator is a direct-drive permanent magnet synchronous machine generating 3-phase power at 240 VAC. The turbine is maintained oriented in to the wind via active yaw control using electromechanical servos. Power is regulated with active blade pitch control. The turbine is presently designed to be placed on a 100-foot (30m) tower. The turbine is predicted to generate electricity at a levelized cost of energy (COE) between 7.3 and 8.9 ¢/kWh at an IEC Class II site, with an average wind speed of 8.5 m/s at hub height, depending upon whether the customer uses a guyed truss tower (the lower figure) or a monopole tower. For the NREL Reference Site, with a mean wind speed of 5.35 m/s at 10 m height, the turbine would generate at a levelized cost of energy of between 9.7 and 11.9 ¢/kWh. The lowest of these numbers is presently competitive with retail electricity rates in most of the country. The 8.9 ¢/kWh is still competitive with retail rates in many regions of the country with high electricity costs. The study further concludes that several design changes could shave 10-14% from the cost of energy determined in the preliminary design. These changes include a new tower design that offers tilt-up capability without guy wires and takes better advantage of the lowered loads produced by pitch control; design a family of airfoils more appropriate for pitch regulation on a turbine of this size; tune the pitch controller properly to minimize shedding of power during turbulent operation in the transition from Region 2 to 3; value engineer the pitch system to shave costs, including consideration of a collective pitch system; and refine the design of the hub and main frame castings to minimize weight and cost. We are generally encouraged by the results. These preliminary numbers show that we can produce a turbine that is competitive with retail electric rates at relatively windy IEC Class II sites. With further improvements in the design, we believe the turbine could be competitive at sites with lesser wind resource.

Wetzel, Kyle K.; McCleer, Patrick J.; Hahlbeck, Edwin C.; DOE Project Office - Keith Bennett

2006-07-21

144

Numerical and experimental flow analysis of the Wang-Zwische double-lumen cannula.  

PubMed

An experimental and numerical analysis was performed for the Wang-Zwische double-lumen cannula (DLC) (Avalon Elite). The aim of this work was to provide insight for future improvement by characterizing the fluid dynamic behavior of the novel catheter with metrics often associated with blood trauma. Pressure and flow distributions were measured on a steady-flow rig using a 50% glycerol-water mixture by imposing a 2 L/min flow rate across the drainage and infusion lumens. The fluid was modeled as Newtonian with density of 1050 kg/m³ and dynamic viscosity of 0.0035 kg/m·s. Reynolds numbers typical for transitional flow (Re = 2000-2500) were computed within the lumens because of the changing cross-sections of the cannula geometry. Numerical computations were performed using the steady three-dimensional Reynolds-averaged Navier-Stokes (RANS) equations and the low-Reynolds k-? turbulence model. Discretization of governing equations was based on a cell-centered finite volume method. Numerical results correlated well with global performance of the cannula, allowing evaluation of the geometry toward potential blood trauma. Peak wall shear stress (WSS) in the drainage lumen was higher than that of infusion lumen, mainly due to the presence of side holes. Furthermore, recirculation regions were predicted in transition tubing to connectors of both the drainage and the infusion lumens because of adverse pressure gradients caused by the sudden enlargement of the cannula geometry. In this three-dimensional computational fluid dynamics (CFD) study, we observed higher peak WSS values for the drainage lumen, which may potentially cause blood trauma. Furthermore, recirculation regions were predicted in the proximity of the exit sections of both the infusion and drainage lumens, which may contribute to thrombosis formation. This study provides insight for future DLC modifications in minimizing cannula-induced blood trauma and thrombogenicity in long-term applications. PMID:21654494

De Bartolo, Carmine; Nigro, Alessandra; Fragomeni, Gionata; Colacino, Francesco M; Wang, Dongfang; Jones, Cameron C; Zwischenberger, Joseph

145

Oral Administration of Ren-Shen-Yang-Rong-Tang 'Ninjin'yoeito' Protects Against Hematotoxicity and Induces Immature Erythroid Progenitor Cells in 5-Fluorouracil-induced Anemia  

PubMed Central

The purpose of this study was to investigate the efficacy of four different Japanese and Chinese herbal prescriptions, Ren-Shen-Yang-Rong-Tang (Ninjin’yoeito, NYT), Chai-Hu-Gui-Zhi-Gan-Jiang-Tang (Saikokeishikankyoto, SKKT), Si-Jun-Zi-Tang (Shikunshito, SKT) and Si-Wu-Tang (Shimotsuto, SMT), which are traditionally used for anemia and fatigue, against hematotoxicity in mice treated with 5-fluorouracil (5-FU). NYT 1–100 mg kg–1 day–1 injected orally for 7 consecutive days before and after 5-FU injection significantly suppressed reductions in red blood cell, white blood cell and platelet counts in peripheral blood, and accelerated their recovery. Administration of SKKT also produced a slight but significant improvement in 5-FU-induced erythrocytopenia, whereas SMT and SKT could not prevent anemia. Oral injection of NYT also inhibited 5-FU-induced decreases in peripheral reticulocyte and bone marrow cell counts on day 10, and markedly hastened their recovery on day 20, in a dose-dependent manner. Erythroid progenitor colonies, such as colony forming units-erythroid and burst forming units-erythroid, formed by marrow cells from mice treated with 5-FU were significantly increased by oral administration of NYT. These findings suggest that NYT has the potential to protect against hematotoxicity, and also has hematopoietic activity, through stimulation of immature erythroid progenitor cell differentiation.

Ohta, Yasuyuki; Tanaka, Tomoaki; Sasaki, Kenroh; Kobayashi, Kyoko; Takahashi, Tomoya; Yahagi, Nobuo; Yoshizaki, Fumihiko; Fushiya, Shinji; Ohta, Tomihisa

2009-01-01

146

Effects of So-cheong-ryong-tang and Yeon-gyo-pae-dok-san on the common cold: Randomized, double blind, placebo controlled trial  

Microsoft Academic Search

Aim of the studySo-cheong-ryong-tang (SCRT) and Yeon-gyo-pae-dok-san (YPS) extracts are widely used in treatment of the common cold. The purpose of this study is to evaluate the efficacy of SCRT and YPS on the common cold.

Jun-Seop Byun; Su-Young Yang; In-Cheol Jeong; Kwon-Eui Hong; Weechang Kang; Yoon Yeo; Yang-Chun Park

2011-01-01

147

Characterization and quantification of eight water-soluble constituents in tubers of Pinellia ternata and in tea granules from the Chinese multiherb remedy Xiaochaihu-tang.  

PubMed

In traditional Chinese medicine, multiple herbs are usually used in combination to generate the joint actions of a multiherb remedy. The recent development of LC-hyphenated techniques enables efficient and rapid profiling of the chemical constituent in extracts from multiherb remedies. Xiaochaihu-tang is a seven-herb remedy that has attracted a great deal of attention for reported ability to treat liver dysfunction. Dried tubers of Pinellia ternata (banxia in Chinese) is one of the ingredients, but its chemical contribution to Xiaochaihu-tang remains poorly understood. In the study presented here, LC-UV-MS, LC-MS-MS, and LC-NMR were used in a complementary manner to determine the nature and content of eight water-soluble constituents of banxia and their presence in various tea granules from Xiaochaihu-tang. Among the eight chemicals identified in banxia, cytidine, adenosine, tryptophan, uridine, and adenine are reported for the first time, while tyrosine, guanosine, and phenylalanine were previously described. These chemicals are also present in all of the samples of Xiaochaihu-tang granules, and the amounts of the chemicals ingested due to a daily dose of the multiherb remedies range from 0.008 to 6.3mg. PMID:16784905

Chen, Ping; Li, Chuan; Liang, Shipiao; Song, Guoqiang; Sun, Yan; Shi, Yanhong; Xu, Songlin; Zhang, Jiwen; Sheng, Shuqun; Yang, Yiming; Li, Min

2006-06-19

148

A Wang-Landau study of a lattice model for lipid bilayer self-assembly  

NASA Astrophysics Data System (ADS)

The Wang-Landau (WL) Monte Carlo method has been applied to simulate the self-assembly of a lipid bilayer on a 3D lattice. The WL method differs from conventional Monte Carlo methods in that a complete density of states is obtained directly for the system, from which properties, such as the free energy, can be derived. Furthermore, from a single WL simulation, continuous curves of the average energy and heat capacity can be determined, which provide a complete picture of the phase behavior. The lipid model studied consists of 3 or 5 coarse-grained segments on lattices of varying sizes, with the empty lattice sites representing water. A bilayer structure is found to form at low temperatures, with phase transitions to clusters as temperature increases. For 3-segment chains, varying lattice sizes were studied, with the observation that the ratio of chain number to lattice area (i.e., area per lipid) affects the phase transition temperature. At small ratios, only one phase transition occurs between the bilayer and cluster phases, while at high lipid ratios the phase transition occurs in a two-step process with a stable intermediate phase. This second phase transition was not observed in conventional Metropolis Monte Carlo simulations on the same model, demonstrating the advantage of being able to perform a complete scan of the whole temperature range with the WL method. For longer 5-segment chains similar phase transitions are also observed with changes in temperature. In the WL method, due to the extensive nature of the energy, the number of energy bins required to represent the density of states increases as the system size increases and so limits its practical application to larger systems. To improve this, an extension of the WL algorithm, the statistical-temperature Monte Carlo method that allows simulations with larger energy bin sizes, has recently been proposed and is implemented in this work for the 3-segment lattice model. The results obtained are in good agreement with the original WL method and appear to be independent of the energy bin size used.

Gai, Lili; Maerzke, Katie A.; Cummings, Peter T.; McCabe, Clare

2012-10-01

149

Factors Affecting Domestic Water Consumption in Rural Households upon Access to Improved Water Supply: Insights from the Wei River Basin, China  

PubMed Central

Comprehensively understanding water consumption behavior is necessary to design efficient and effective water use strategies. Despite global efforts to identify the factors that affect domestic water consumption, those related to domestic water use in rural regions have not been sufficiently studied, particularly in villages that have gained access to improved water supply. To address this gap, we investigated 247 households in eight villages in the Wei River Basin where three types of improved water supply systems are implemented. Results show that domestic water consumption in liters per capita per day was significantly correlated with water supply pattern and vegetable garden area, and significantly negatively correlated with family size and age of household head. Traditional hygiene habits, use of water appliances, and preference for vegetable gardening remain dominant behaviors in the villages with access to improved water supply. Future studies on rural domestic water consumption should pay more attention to user lifestyles (water appliance usage habits, outdoor water use) and cultural backgrounds (age, education).

Fan, Liangxin; Liu, Guobin; Wang, Fei; Geissen, Violette; Ritsema, Coen J.

2013-01-01

150

Shape Variation in Aterian Tanged Tools and the Origins of Projectile Technology: A Morphometric Perspective on Stone Tool Function  

PubMed Central

Background Recent findings suggest that the North African Middle Stone Age technocomplex known as the Aterian is both much older than previously assumed, and certainly associated with fossils exhibiting anatomically modern human morphology and behavior. The Aterian is defined by the presence of ‘tanged’ or ‘stemmed’ tools, which have been widely assumed to be among the earliest projectile weapon tips. The present study systematically investigates morphological variation in a large sample of Aterian tools to test the hypothesis that these tools were hafted and/or used as projectile weapons. Methodology/Principal Findings Both classical morphometrics and Elliptical Fourier Analysis of tool outlines are used to show that the shape variation in the sample exhibits size-dependent patterns consistent with a reduction of the tools from the tip down, with the tang remaining intact. Additionally, the process of reduction led to increasing side-to-side asymmetries as the tools got smaller. Finally, a comparison of shape-change trajectories between Aterian tools and Late Paleolithic arrowheads from the North German site of Stellmoor reveal significant differences in terms of the amount and location of the variation. Conclusions/Significance The patterns of size-dependent shape variation strongly support the functional hypothesis of Aterian tools as hafted knives or scrapers with alternating active edges, rather than as weapon tips. Nevertheless, the same morphological patterns are interpreted as one of the earliest evidences for a hafting modification, and for the successful combination of different raw materials (haft and stone tip) into one implement, in itself an important achievement in the evolution of hominin technologies.

Iovita, Radu

2011-01-01

151

Subacute toxicity and stability of Soshiho-tang, a traditional herbal formula, in Sprague-Dawley rats  

PubMed Central

Backgroud Soshiho-tang (SST, Xiao-chai-hu-tang in Chinese and Sho-saiko-to in Japanese), an oriental herbal formula, is used for treatment of chronic liver diseases. Although many researchers have studied the pharmacological properties of SST, information about its safety and toxicity is limited. Therefore, we evaluated the potential safety of SST in Sprague–Dawley rats over a period of 4-weeks. Methods The SST was administered once daily by gavage to male and female rats at doses of 0, 500, 1000 and 2000 mg/kg/day for 4 weeks. We measured the body weight, mortality, food consumption, ophthalmoscopy, urinalysis, hematology, serum biochemistry, gross pathological findings, absolute/relative organ weights and histopathology. In addition, we analyzed the component of SST and measured the stability of its component in SST according to study periods using high performance liquid chromatography. Results The SST treatment did not result in any toxicologically significant changes in mortality, food consumption, ophthalmoscopy, urinalysis, hematology, serum biochemistry, gross pathological findings, absolute/relative organ weights and histopathology, except for salivation and reduction in body weight in the 2000 mg/kg/day male group. These findings in the 2000 mg/kg/day male group are considered toxicologically insignificant because they are not accompanied by other pathological findings, including in hematology, serum biochemistry and histopatholgy, and they do not exhibit a dose–response relationship. SST is detected three components including liquiritin, baicalin, and glycyrrhizin. In addition, there were not observed the significant differences among the contents of three components in SST according to storage periods. Conclusion These results indicate that SST may be a safe material. Based on these results, the no-observed-adverse-effect level was more than 2000 mg/kg for both genders.

2012-01-01

152

Banha-sasim-tang as an herbal formula for the treatment of functional dyspepsia: a randomized, double-blind, placebo-controlled, two-center trial  

PubMed Central

Background Functional dyspepsia (FD) is characterized by a high prevalence rate and no standard conventional treatments. Alternative therapies, such as herbal formulas, are widely used to treat FD. However, there are inadequate evidences regarding the safety and efficacy of these formulas. Moreover, the mechanisms by which herbal formulas act in the gastrointestinal tract are controversial. In traditional Korean medicine, Banha-sasim-tang has long been one of the most frequently prescribed herbal formulas for treating dyspepsia. The current study is designed to evaluate the efficacy and safety of Banha-sasim-tang for FD patients and to examine whether there will be a significant correlation between cutaneous electrogastrography recordings and dyspeptic symptoms in FD patients, and between changes in gastric myoelectrical activity and improvement in dyspeptic symptoms during Banha-sasim-tang administration. Methods This randomized, double-blind, placebo-controlled trial will be performed at two centers and will include a Banha-sasim-tang group and placebo group. Each group will consist of 50 FD patients. Six weeks of administration of Banha-sasim-tang or placebo will be conducted. During the subsequent 2 months, follow-up observations of primary and secondary outcomes will be performed. The primary outcomes are differences as measured on the gastrointestinal symptom scale, and the secondary outcomes are differences as measured on the visual analogue scale for dyspepsia and on the questionnaire for FD-related quality of life. All outcomes will be measured at baseline, at 2, 4, and 6 weeks of treatment, and at the 1 and 2 month follow-up. Cutaneous electrogastrography will be performed and assessed at baseline and at 6 weeks. Discussion This trial will provide evidence of the safety and efficacy of Banha-sasim-tang for the treatment for FD. Furthermore, based on the assessment of the relationship between cutaneous electrogastrography recordings and dyspeptic symptoms in this trial, the possibility of clinical applications of cutaneous electrogastrography in the treatment of FD will be elucidated. Trial Registration Current Controlled Trials (ISRCTN 51910678); Clinical Trials.gov Identifier: NCT00987805

2010-01-01

153

GPU-based Swendsen-Wang multi-cluster algorithm for the simulation of two-dimensional classical spin systems  

NASA Astrophysics Data System (ADS)

We present the GPU calculation with the common unified device architecture (CUDA) for the Swendsen-Wang multi-cluster algorithm of two-dimensional classical spin systems. We adjust the two connected component labeling algorithms recently proposed with CUDA for the assignment of the cluster in the Swendsen-Wang algorithm. Starting with the q-state Potts model, we extend our implementation to the system of vector spins, the q-state clock model, with the idea of embedded cluster. We test the performance, and the calculation time on GTX580 is obtained as 2.51 nsec per a spin flip for the q=2 Potts model (Ising model) and 2.42 nsec per a spin flip for the q=6 clock model with the linear size L=4096 at the critical temperature, respectively. The computational speed for the q=2 Potts model on GTX580 is 12.4 times as fast as the calculation speed on a current CPU core. That for the q=6 clock model on GTX580 is 35.6 times as fast as the calculation speed on a current CPU core.

Komura, Yukihiro; Okabe, Yutaka

2012-06-01

154

SIMULTANEOUS DETERMINATION AND PHARMACOKINETIC COMPARISONS OF ALOE-EMODIN, RHEIN, EMODIN, AND CHRYSOPHANOL AFTER ORAL ADMINISTRATION OF THESE MONOMERS, RHEI RHIZOMA AND CHAIQIN-CHENGQI-TANG, TO RATS  

Microsoft Academic Search

A study was conducted to compare the pharmacokinetics of aloe-emodin, rhein, emodin, and chrysophanol after oral administration of these monomers, Rhei Rhizoma and Chaiqin-Chengqi-Tang, to rats. Separation of the monomers in rat plasma was accomplished on a YMC C18 stationary phase (4.6 × 150 mm, 5 µm) and a mobile phase of methanol-water containing 0.2% acetic acid (70:30, v\\/v), with a UV detector setting

Feng Qin; Jun Huang; Xi Huang; Ping Ren

2011-01-01

155

Chungsim-Yeunja-Tang decreases the inflammatory response in peripheral blood mononuclear cells from patients with cerebral infarction through an NF-?B dependent mechanism  

Microsoft Academic Search

BACKGROUND: Chungsim-Yeunja-Tang (CYT) has been used as a medicine for cerebral infarction (CI) patients in Korea. The objective of this study was to determine precisely the effect of CYT on CI patients using peripheral blood mononuclear cells (PBMCs). METHODS: For a clinical study, 47 CI patients were identified who had taken CYT (0.01 g\\/kg) 3 times a day after meals

Hyun-Ja Jeong; In-Young Choi; Min-Ho Kim; Hyung-Min Kim; Phil-Dong Moon; Jin-Woo Hong; Soo-Hyun Kim

2010-01-01

156

Antidepressant-like effects of the saponins extracted from Chaihu-jia-longgu-muli-tang in a rat unpredictable chronic mild stress model  

Microsoft Academic Search

Chaihu-jia-longgu-muli-tang (CLM) has been used for treating depressive disorders for thousands of years in China. In the present study, we investigated the antidepressant-like effect of the saponins extracted from CLM (SCLM) in rats subjected to unpredictable chronic mild stress (UCMS). The ameliorative effect of SCLM on symptom of depression through behavior tests including: sucrose preference test, open-field test and forced-swimming

Lu-Fan Li; Jie Lu; Xiu-Min Li; Chang-Liang Xu; Jie Yang; Rong Qu; Shi-Ping Ma

157

Effects of Hyul-Bu-Chuke-Tang on Erythrocyte Deformability and Cerebrovascular CO2 Reactivity in Normal Subjects  

PubMed Central

Aim. Hyul-bu-chuke-tang (HCEt) is a well-known traditional herbal medicine that is used for the treatment of ischemic cerebrovascular disorders. We investigated the acute effects of HCEt on erythrocyte deformability and cerebrovascular CO2 reactivity (CVR) in healthy male subjects. Materials and Methods. We examined erythrocyte deformability in an HCEt group (n = 14) and a control group (n = 10). CVR was measured using hyperventilation-induced CO2 reactivity of the middle cerebral artery and transcranial Doppler (TCD) in the HCEt group (n = 11). A historical control group (n = 10) of CVR measurements was also created from our previous study. All measurements were performed prior to and 1, 2, and 3 hours after HCEt administration. Results. HCEt significantly improved erythrocyte deformability 1 hour after administration compared to the control group (2.9 ± 1.1% versus ?0.6 ± 1.0%, P = 0.034). HCEt significantly improved the CVR 2 hours after administration compared to the historical control group (9.1 ± 4.0% versus ?8.1 ± 4.1%, P = 0.007). The mean blood pressure and pulse rate did not vary from baseline values in either group. Conclusions. We demonstrated that HCEt improved erythrocyte deformability and CVR. Our findings suggest that an improvement in erythrocyte deformability contributes to HCEt's effect on cerebral microcirculation.

Jung, Woo-Sang; Park, Joo-Young; Byeon, Hyung-Sik; Kim, Young-Jee; Park, Jung-Mi; Park, Seong-Uk; Cho, Seung-Yeon; Moon, Sang-Kwan

2012-01-01

158

Renal protective effect of xiao-chai-hu-tang on diabetic nephropathy of type 1-diabetic mice.  

PubMed

Xiao-Chai-Hu-Tang (XCHT), a traditional Chinese medicine formula consisting of seven medicinal plants, is used in the treatment of various diseases. We show here that XCHT could protect type-1 diabetic mice against diabetic nephropathy, using streptozotocin (STZ)-induced diabetic mice and high-glucose (HG)-exposed rat mesangial cell (RMC) as models. Following 4 weeks of oral administration with XCHT, renal functions and renal hypertrophy significantly improved in the STZ-diabetic mice, while serum glucose was only moderately reduced compared to vehicle treatment. Treatment with XCHT in the STZ-diabetic mice and HG-exposed RMC resulted in a decrease in expression levels of TGF-?1, fibronectin, and collagen IV, with concomitant increase in BMP-7 expression. Data from DPPH assay, DHE stain, and CM-H(2)DCFDA analysis indicated that XCHT could scavenge free radicals and inhibit high-glucose-induced ROS in RMCs. Taken together, these results suggest that treatment with XCHT can improve renal functions in STZ-diabetic mice, an effect that is potentially mediated through decreasing oxidative stress and production of TGF-?1, fibronectin, and collagen IV in the kidney during development of diabetic nephropathy. XCHT, therefore merits further investigation for application to improve renal functions in diabetic disorders. PMID:22474533

Lin, Chun-Ching; Lin, Liang-Tzung; Yen, Ming-Hong; Cheng, Juei-Tang; Hsing, Chung-Hsi; Yeh, Ching-Hua

2012-03-07

159

In vitro and in vivo assessment of cytochrome P450-mediated herb-drug interaction of Ssang-hwa-tang.  

PubMed

We have evaluated the herb-drug interaction potential of Ssang-hwa-tang (SHT) mediated by cytochrome P450 (CYP) inhibition/induction. Further, the effects of fermentation on the CYP-mediated herb-drug interaction potential were determined. SHT showed inhibitory activity toward CYP1A2, but not 2A6, 2B6, 2C9, 2C19, 2D6, 2E1, and 3A4 in human liver microsomes. The results of the enzyme kinetic study suggested that the SHT-induced CYP1A2 inhibition is mixed reversible inhibition. The hepatic CYP expression and activity in rats treated with SHT were examined. The expression/activity of CYP2E1 increased as a result of SHT extract treatment (P<0.005 or P<0.001, respectively), which raises the possibility that SHT may increase the toxicity of environmental toxicants through the elevation of CYP2E1-mediated metabolic activation. SHT fermentation using Lactobacillus fermentum or Lactobacillus gasseri resulted in attenuation of the SHT-induced CYP1A2 inhibition, but not CYP2E1 induction, suggesting that changes in the chemical composition of SHT through fermentation can affect the inhibition of CYP1A2 activity. PMID:23122083

Lee, Sang Yoon; Lee, Ji-Yoon; Kang, Wonku; Kwon, Kwang-il; Oh, Soo Jin; Ma, Jin Yeul; Kim, Sang Kyum

2012-09-07

160

Effects of Hange-koboku-to (Banxia-houpo-tang) on neuropeptide levels in human plasma and saliva.  

PubMed

Hange-koboku-to (Banxia-houpo-tang), a Chinese herbal (Kampo) medicine, has been used for improvement of hoarse voice, something foreign body sensation in the throat and/or esophagus, and swallowing reflex, among other conditions. One of the mechanisms of the empirical effects is assumed to be due to local changes in neuropeptide levels locally. We investigated the effects of Hange-koboku-to on neuropeptides, calcitonin gene-related peptide (CGRP), substance P, somatostatin, and vasoactive intestinal peptide (VIP) in plasma and saliva, as well as on salivary secretion in healthy subjects. A single oral administration of Hange-koboku-to caused significant increases in substance P-immunoreactive substance (IS) (40 min) in plasma, and slightly increased in CGRP-IS and somatostatin-IS in plasma compared with placebo. In saliva neuropeptides, Hange-koboku-to caused significant increases in substance P-IS (20 min) and somatostatin-IS (40, 60 min), and a slight increase in VIP-IS. However, a single Hange-koboku-to stimulation did not have a significant effect of sialosis volume. These results seem to suggest that Hange-koboku-to improves hoarse voice, something foreign body sensation in the throat and esophagus, and swallowing reflex disorder, by stimulation of neuropeptidergic nerves locally. PMID:14600411

Naito, Takafumi; Itoh, Hiroki; Takeyama, Masaharu

2003-11-01

161

Factors Affecting Domestic Water Consumption in Rural Households upon Access to Improved Water Supply: Insights from the Wei River Basin, China.  

PubMed

Comprehensively understanding water consumption behavior is necessary to design efficient and effective water use strategies. Despite global efforts to identify the factors that affect domestic water consumption, those related to domestic water use in rural regions have not been sufficiently studied, particularly in villages that have gained access to improved water supply. To address this gap, we investigated 247 households in eight villages in the Wei River Basin where three types of improved water supply systems are implemented. Results show that domestic water consumption in liters per capita per day was significantly correlated with water supply pattern and vegetable garden area, and significantly negatively correlated with family size and age of household head. Traditional hygiene habits, use of water appliances, and preference for vegetable gardening remain dominant behaviors in the villages with access to improved water supply. Future studies on rural domestic water consumption should pay more attention to user lifestyles (water appliance usage habits, outdoor water use) and cultural backgrounds (age, education). PMID:23977190

Fan, Liangxin; Liu, Guobin; Wang, Fei; Geissen, Violette; Ritsema, Coen J

2013-08-16

162

Role of Peltigera rufescens (Weis) Humb. (a lichen) on imazalil-induced genotoxicity: analysis of micronucleus and chromosome aberrations in vitro.  

PubMed

Imazalil (IMA), a commonly used fungicide in both agricultural and clinical domains, is suspected to produce very serious toxic effects on vertebrates. On the other hand, in recent years, a number of studies have suggested that lichens might be easily accessible sources of natural drugs that could be used as a possible food supplement. Extensive research is being carried out to explore the importance of lichen species, which are known to contain a variety of pharmacological active compounds. In this context, the anti-genotoxic effects of aqueous Peltigera rufescens (Weis) Humb. extracts (PREs) were studied against the genotoxic damage induced by IMA on cultured human lymphocytes using chromosomal aberrations (CAs) and micronucleus (MN) as cytogenetic parameters. Human peripheral lymphocytes were treated in vitro with varying concentrations of PREs (0, 5, 10, 25, 50 and 100 mg/L), tested in combination with IMA (336 mg/L). PREs alone were not genotoxic and when combined with IMA treatment, reduced the frequency of CAs and the rates of MNs. A clear dose-dependent decrease in the genotoxic damage of IMA was observed, suggesting a genoprotective role of P. rufescens extract. The results of the present study indicate that this plant extract per se do not have genotoxic potential but can minimize the genotoxicity of IMA on human lymphocytes in vitro. In conclusion our findings may have an important application for the protection of human lymphocyte from the genetic damage and side effects induced by agricultural and medical chemicals hazardous in people. PMID:21937535

Türkez, Hasan; Aydin, Elanur; Si?man, Turgay; Aslan, Ali

2011-09-21

163

Particle-induced oxidative damage of indoor PM10 from coal burning homes in the lung cancer area of Xuan Wei, China  

NASA Astrophysics Data System (ADS)

The lung cancer mortality rate in the rural area of the Xuan Wei, Yunnan, is among the highest in China, especially in women. In this paper, the coal-burning indoor and corresponding outdoor PM10 samples were collected at the Hutou village, representing the case of high lung cancer rate, and the Xize village, representing the case of low lung cancer rate. Plasmid scission assay was used to investigate the bioreactivity of the PM10. The inductively coupled plasma-mass spectrometry (ICP-MS) was employed to investigate the trace element compositions of the PM10. The results showed that the oxidative damage caused by both indoor and outdoor PM10 at the Hutou village was obviously higher than that at the Xize village, with the indoor PM10 having higher oxidative damage than corresponding outdoors. Among all analyzed samples, the indoor night PM10 samples from the Hutou village have the highest oxidative capacity. The levels of total water-soluble elements had a higher level in the PM10 of the Hutou village than that of the Xize village. It is interesting that the levels of water-soluble As, Cd, Cs, Pb, Sb, Tl and Zn in PM10 had better positive correlation with DNA damage rates, implying that these elements in their water-soluble state should be one of the main factors responsible for the high oxidative capacity of PM10, thus possibly the higher lung cancer rates, at the Hutou village.

Shao, Longyi; Hu, Ying; Wang, Jing; Hou, Cong; Yang, Yuanyuan; Wu, Mingyuan

2013-10-01

164

Mouse skin tumorigenicity studies of indoor coal and wood combustion emissions from homes of residents in Xuan Wei, China with high lung cancer mortality  

SciTech Connect

The rural Xuan Wei County, Yunnan Province, China, has an unusually high lung cancer mortality rate that cannot be attributed to tobacco smoke or occupational exposure. The lung cancer rate is associated with 'smoky' coal, in contrast to wood or 'smokeless' coal burned in unventilated homes. The study was conducted to characterize and compare mouse skin tumorigenicity of the coal and the wood combustion emissions and to link the resulting animal data to human lung cancer. Indoor air particles were collected from a central commune where the lung cancer mortality rate is high and smoky coal is the major fuel used, and also from a south western commune where lung cancer mortality rate is low and wood and smokeless coal are the major fuels used. The organic extracts of these indoor air particles were analyzed for polycyclic aromatic hydrocarbons (PAHs) and assayed for skin tumor initiation activity and complete carcinogenicity in SENCAR mice. Mouse skin was initiated with 1,2,5,10, and 20 mg of organic extracts of the emission particles during the first week, and one week after initiation the mice were promoted with 12-0-tetradecanoylphorbol-13-acetate (TPA, 2 microgram/mouse) applied topically twice a week for 26 weeks. The results showed that the smoky coal sample is the most active among the three combustion emission samples.

Mumford, J.L.; Helmes, C.T.; Lee, X.; Seidenberg, J.; Nesnow, S.

1990-01-01

165

Assessment of Impact of Insecticides on Anagrus nilaparvatae (Pang et Wang) (Hymenoptera: Mymanidae), an Egg Parasitoid of the Rice Planthopper, Nilaparvata lugens (Hemiptera: Delphacidae)  

Technology Transfer Automated Retrieval System (TEKTRAN)

The parasitoid Anagrus Nilaparvatae (Pang et Wang) (Hymenoptera: Mymanidae) is a major natural enemy of the rice planthopper Nilaparvata lugens (Hemiptera: Delphacidae). It plays an important role in the IPM of the rice planthopper. Contact and oral toxicity and residual effect of fourteen pesticide...

166

Two Simple Approaches to Overcome a Problem with the Mantel-Haenszel Statistic: Comments on Wang, Bradlow, Wainer, and Muller (2008)  

ERIC Educational Resources Information Center

|The Mantel-Haenszel (MH) procedure (Mantel and Haenszel) is a popular method for estimating and testing a common two-factor association parameter in a 2 x 2 x K table. Holland and Holland and Thayer described how to use the procedure to detect differential item functioning (DIF) for tests with dichotomously scored items. Wang, Bradlow, Wainer,…

Sinharay, Sandip; Dorans, Neil J.

2010-01-01

167

Warranted Neo-Confucian belief: Religious pluralism and the affections in the epistemologies of Wang Yangming (1472–1529) and Alvin Plantinga  

Microsoft Academic Search

In this article, I argue that Wang Yangming'sNeo-Confucian religious beliefs can bewarranted, and that the rationality of hisreligious beliefs constitutes a significantdefeater for the rationality of Christianbelief on Alvin Plantinga's theory of warrant. I also question whether the notion of warrantas proper function can adequately account fortheories of religious knowledge in which theaffections play an integral role. Idemonstrate how a

David W. Tien

2004-01-01

168

Lactobacillus fermentation enhances the inhibitory effect of Hwangryun-haedok-tang in an ovariectomy-induced bone loss  

PubMed Central

Background Hwangryun-haedok-tang (HRT) is traditional herbal medicine used to treat inflammatory-related diseases in Asia. However, its effect on osteoclastogenesis and bone loss is still unknown. In this study, we evaluated the effect of HRT and its fermented product (fHRT) on the receptor activator for the nuclear factor-?B ligand-induced osteoclastogenesis using murine bone marrow-derived macrophages and postmenopausal bone loss using an ovariectomy (OVX) rat model. Methods Tartrate resistant acid phosphatase (TRAP) staining was employed to evaluate osteoclast formation. mRNA level of transcription factor and protein levels of signaling molecules were determined by real-time quantitative polymerase chain reaction and Western blot analysis, respectively. Effect of HRT or fHRT on OVX-induced bone loss was evaluated using OVX rats orally administered HRT, or fHRT with 300 mg/kg for 12 weeks. Micro-CT analysis of femora was performed to analyze bone parameter. Results HRT or fHRT treatment significantly decreased TRAP activity and the number of TRAP positive multinuclear cells on osteoclastogenesis. Interestingly, these inhibitory effects of HRT were enhanced by fermentation. Furthermore, fHRT significantly inhibited mRNA and protein expression of nuclear factor of activated T cells cytoplasmic 1, which leads to down-regulation of NFATc1-regulated mRNA expressions such as TRAP, the d2 isoform of vacuolar ATPase V(0) domain, and cathepsin K. Administration of fHRT significantly inhibited the decrease of bone mineral density, and improved bone parameter of femora more than that of HRT and vehicle in OVX rats. Conclusions This study demonstrated that lactic bacterial fermentation fortifies the inhibitory effect of HRT on osteoclastogenesis and bone loss. These results suggest that fermented HRT might have the beneficial potential on osteoporosis by inhibiting osteoclastogenesis.

2013-01-01

169

Action Mechanisms of Du-Huo-Ji-Sheng-Tang on Cartilage Degradation in a Rabbit Model of Osteoarthritis  

PubMed Central

Du-Huo-Ji-Sheng-Tang (DHJST) is a traditional Chinese herbal medicine used to treat osteoarthritis. In the present study, the therapeutic effect of DHJST on cartilage degradation in a rabbit model of osteoarthritis was investigated. In the knee joints of rabbits, anterior cruciate ligament transection (ACLT) was performed to induce experimental osteoarthritis. At the end of the sixth week, 30 rabbits with ACLT were divided into six groups, control group, DHJST group and Osaminethacine (OSA) group, which were followed for another 4 weeks. The other three groups of rabbits with ACLT were untreated with DHJST or OSA, which were sacrificed after 6 weeks, and served as 6-week time point controls. Results indicated that at the end of the sixth week after surgery, there was a significantly histological degeneration in the control group compared with the normal group. In the control group, the mean score for histological degeneration were further increases at 10th week, and there was a significantly lower mean score for histological degeneration in the DHJST group compared with the control group. To research the potential mechanism, the expression level of VEGF and HIF-1? were detected. The expression of VEGF mRNA and HIF-1? mRNA are low in normal group, while the activities increase gradually in the control group. However, compared to that of the same time point model group, activity of VEGF and HIF-1? decreased significantly in DHJST group. In conclusion, DHJST exerts significant therapeutic effect on osteoarthritis rabbits, and mechanisms are associated with inhibition of VEGF and HIF-1? expression.

Chen, Chao-Wei; Sun, Jian; Li, Yu-Mei; Shen, Pi-An; Chen, Yong-Qiang

2011-01-01

170

Overcoming barriers in trajectory space: Mechanism and kinetics of rare events via Wang-Landau enhanced transition path sampling  

NASA Astrophysics Data System (ADS)

Within the framework of transition path sampling (TPS), activation energies can be computed as path ensemble averages without a priori information about the reaction mechanism [C. Dellago and P. G. Bolhuis, Mol. Simul. 30, 795 (2004)]. Activation energies computed for different conditions can then be used to determine by numerical integration the rate constant for a system of interest from the rate constant known for a reference system. However, in systems with complex potential energy surfaces, multiple reaction pathways may exist making ergodic sampling of trajectory space difficult. Here, we present a combination of TPS with the Wang-Landau (WL) flat-histogram algorithm for an efficient sampling of the transition path ensemble. This method, denoted by WL-TPS, has the advantage that from one single simulation, activation energies at different temperatures can be determined even for systems with multiple reaction mechanisms. The proposed methodology for rate constant calculations does not require the knowledge of the reaction coordinate and is generally applicable to Arrhenius and non-Arrhenius processes. We illustrate the applicability of this technique by studying a two-dimensional toy system consisting of a triatomic molecule immersed in a fluid of repulsive soft disks. We also provide an expression for the calculation of activation volumes from path averages such that the pressure dependence of the rate constant can be obtained by numerical integration.

Borrero, Ernesto E.; Dellago, Christoph

2010-10-01

171

Optimized Wang-Landau sampling of lattice polymers: Ground state search and folding thermodynamics of HP model proteins  

NASA Astrophysics Data System (ADS)

Coarse-grained (lattice-) models have a long tradition in aiding efforts to decipher the physical or biological complexity of proteins. Despite the simplicity of these models, however, numerical simulations are often computationally very demanding and the quest for efficient algorithms is as old as the models themselves. Expanding on our previous work [T. Wüst and D. P. Landau, Phys. Rev. Lett. 102, 178101 (2009)], we present a complete picture of a Monte Carlo method based on Wang-Landau sampling in combination with efficient trial moves (pull, bond-rebridging, and pivot moves) which is particularly suited to the study of models such as the hydrophobic-polar (HP) lattice model of protein folding. With this generic and fully blind Monte Carlo procedure, all currently known putative ground states for the most difficult benchmark HP sequences could be found. For most sequences we could also determine the entire energy density of states and, together with suitably designed structural observables, explore the thermodynamics and intricate folding behavior in the virtually inaccessible low-temperature regime. We analyze the differences between random and protein-like heteropolymers for sequence lengths up to 500 residues. Our approach is powerful both in terms of robustness and speed, yet flexible and simple enough for the study of many related problems in protein folding.

Wüst, Thomas; Landau, David P.

2012-08-01

172

Comparison of the Wang 19-gauge and 22-gauge needles in the mediastinal staging of lung cancer.  

PubMed

Transbronchial needle aspiration (TBNA) offers the unique opportunity to pathologically stage patients with lung cancer at the time of diagnostic bronchoscopy. The purpose of this study was to compare the staging sensitivities of the Wang 22-gauge and 19-gauge needles. We studied 64 patients with bronchogenic carcinoma and mediastinal adenopathy. Before bronchoscopy each patient underwent chest CT. Three to four aspirates were obtained with each needle from endotracheal sites adjacent to paratracheal lymphadenopathy. In 47 patients malignant mediastinal adenopathy was confirmed by the 19-gauge needle. A total of 29 patients had malignant 22-gauge needle aspirates. Of the 64 patients, 9 had benign, reactive mediastinal lymph nodes. There were 20 patients in whom only the 19-gauge needle demonstrated malignancy and 2 patients with malignant 22-gauge needle aspirates as the sole identifier of paratracheal malignancy. As a staging tool, the 19-gauge needle was significantly more sensitive than the 22-gauge needle, 85.5 versus 52.7% (p = 0.0001). Overall, in 49 of 55 patients (89.1%) with malignant mediastinal lymphadenopathy paratracheal tumor was confirmed by TBNA. The 19-gauge TBNA staging of the mediastinum is an effective, safe, and cost-saving alternative to surgical mediastinal exploration that can be performed during initial diagnostic bronchoscopy. PMID:8484639

Schenk, D A; Chambers, S L; Derdak, S; Komadina, K H; Pickard, J S; Strollo, P J; Lewis, R E; Patefield, A J; Henderson, J H; Tomski, S M

1993-05-01

173

Discovery of Molecular Mechanisms of Traditional Chinese Medicinal Formula Si-Wu-Tang Using Gene Expression Microarray and Connectivity Map  

PubMed Central

To pursue a systematic approach to discovery of mechanisms of action of traditional Chinese medicine (TCM), we used microarrays, bioinformatics and the “Connectivity Map” (CMAP) to examine TCM-induced changes in gene expression. We demonstrated that this approach can be used to elucidate new molecular targets using a model TCM herbal formula Si-Wu-Tang (SWT) which is widely used for women's health. The human breast cancer MCF-7 cells treated with 0.1 µM estradiol or 2.56 mg/ml of SWT showed dramatic gene expression changes, while no significant change was detected for ferulic acid, a known bioactive compound of SWT. Pathway analysis using differentially expressed genes related to the treatment effect identified that expression of genes in the nuclear factor erythroid 2-related factor 2 (Nrf2) cytoprotective pathway was most significantly affected by SWT, but not by estradiol or ferulic acid. The Nrf2-regulated genes HMOX1, GCLC, GCLM, SLC7A11 and NQO1 were upreguated by SWT in a dose-dependent manner, which was validated by real-time RT-PCR. Consistently, treatment with SWT and its four herbal ingredients resulted in an increased antioxidant response element (ARE)-luciferase reporter activity in MCF-7 and HEK293 cells. Furthermore, the gene expression profile of differentially expressed genes related to SWT treatment was used to compare with those of 1,309 compounds in the CMAP database. The CMAP profiles of estradiol-treated MCF-7 cells showed an excellent match with SWT treatment, consistent with SWT's widely claimed use for women's diseases and indicating a phytoestrogenic effect. The CMAP profiles of chemopreventive agents withaferin A and resveratrol also showed high similarity to the profiles of SWT. This study identified SWT as an Nrf2 activator and phytoestrogen, suggesting its use as a nontoxic chemopreventive agent, and demonstrated the feasibility of combining microarray gene expression profiling with CMAP mining to discover mechanisms of actions and to identify new health benefits of TCMs.

Wen, Zhining; Wang, Zhijun; Wang, Steven; Ravula, Ranadheer; Yang, Lun; Xu, Jun; Wang, Charles; Zuo, Zhong; Chow, Moses S. S.; Shi, Leming; Huang, Ying

2011-01-01

174

Comment to “Chlorine stable isotopes and halogen concentrations in convergent margins with implications for the Cl isotopes cycle in the ocean” by Wei et al. A review of the Cl isotope composition of serpentinites and the global chlorine cycle  

NASA Astrophysics Data System (ADS)

Wei et al. [Wei, W., Kastner, M., Spivack, A., 2008. Chlorine stable isotope and halogen concentrations in convergent margins with implications for the Cl isotopes cycle in the ocean. Earth Planet. Sci. Lett. 266, 90 104] published chlorine isotope data for pore fluids and serpentinites from three subduction zones and two obducted serpentinites. The measured ?37Cl values of serpentinites ranged from 1.2 to 6.0‰ (vs. SMOC), far higher than all other published data for serpentinites. The explanation for these high ?37Cl values defies known fractionation mechanisms. Instead, the anomalous ?37Cl values are almost certainly due to analytical artifacts known to exist for the method the authors employed. Wei et al. [Wei, W., Kastner, M., Spivack, A., 2008. Chlorine stable isotope and halogen concentrations in convergent margins with implications for the Cl isotopes cycle in the ocean. Earth Planet. Sci. Lett. 266, 90 104] concluded that if high ?37Cl serpentinites (˜ 6‰) were subducted into the mantle, then a change in the ?37Cl value of the crustal reservoir would be observed in the evaporite record over the last 200Ma. Because the Cl isotope composition of the crustal reservoirs has been constant over this time period, as constrained by evaporites, they argue that Cl in serpentinites is recycled back to the oceans. This argument is flawed for two reasons. First, the ?37Cl values of serpentinites is close to 0‰, not 6‰ as suggested in their paper. Second, the ?37Cl value of the crustal reservoir would change immeasurably over 200Ma even if serpentinites of 6‰ were subducted into the mantle. In fact, it has been shown that the crust, mantle and chondritic reservoir all have ?37Cl values close to 0‰ [Sharp, Z.D., Barnes, J.D., Brearley, A.J., Fischer, T.P., Chaussidon, M., Kamenetsky, V.S., 2007. Chlorine isotope homogeneity of the mantle, crust and carbonaceous chondrites. Nature 446, 1062 1065]. No secular variation in the ?37Cl value of the crust is expected, a conclusion that is supported by chlorine isotope data on sediments extending back over 3.5Ga [Sharp, Z.D., Barnes, J.D., Brearley, A.J., Fischer, T.P., Chaussidon, M., Kamenetsky, V.S., 2007. Chlorine isotope homogeneity of the mantle, crust and carbonaceous chondrites. Nature 446, 1062 1065].

Sharp, Z. D.; Barnes, J. D.

2008-10-01

175

Analysis of the magnetic field discontinuity at the potential field source surface and Schatten Current Sheet interface in the Wang–Sheeley–Arge model  

Microsoft Academic Search

The Wang–Sheeley–Arge solar wind model makes use of coupled potential field source surface (PFSS) and Schatten Current Sheet (SCS) models to reconstruct the coronal magnetic field on the basis of the observed line-of-sight photospheric magnetic field and a 1D kinematic code to propagate the solar wind to 1 AU. The source surface serves as the outer boundary of the PFSS

S. L. McGregor; W. J. Hughes; C. N. Arge; M. J. Owens

2008-01-01

176

LANDSLIDE PREDICTION MODEL USING REMOTE SENSING, GIS AND FIELD GEOLOGY: A CASE STUDY OF WANG CHIN DISTRICT, PHRAE PROVINCE, NORTHERN THAILAND  

Microsoft Academic Search

This study, landslide hazard potential and prediction model were assessed at regional scale (1:50,000 to 1: 100,000) using remote sensing, geographic information systems (GIS) and field geology. The case study area is at Wang Chin District, Phrae Province, Northern Thailand. The role of remote sensing is mainly to map the distribution of existing landslides location and the factors that affect

Suree Teerarungsigul; Chongpan Chonglakmani; Friedrich Kuehn

177

Verification of the formulation and efficacy of Danggui Buxue Tang (a decoction of Radix Astragali and Radix Angelicae Sinensis): an exemplifying systematic approach to revealing the complexity of Chinese herbal medicine formulae  

Microsoft Academic Search

This article exemplifies a systematic approach to revealing the complexity of Chinese herbal medicine formulae through three levels of scientific research: standardization of herbs, verification of ancient formulae and mechanism studies. We use Danggui Buxue Tang (DBT) as an example for this approach. Among thousands of traditional Chinese medicine herbal formulae, almost all of which consist of multiple herbs, DBT

Qiutao Gao; Jun Li; Jerry Ka Hei Cheung; Jinao Duan; Anwei Ding; Anna Wing Han Cheung; Kuijun Zhao; Winnie Zhuoming Li; Tina Tingxia Dong; Karl Wah Keung Tsim

2007-01-01

178

Quality evaluation of commercial Huang-Lian-Jie-Du-Tang based on simultaneous determination of fourteen major chemical constituents using high performance liquid chromatography.  

PubMed

Huang-Lian-Jie-Du-Tang (HLJDT), comprising Coptidis Rhizoma, Scutellariae Radix, Phellodendri Cortex and Gardeniae Fructus, is one of the commonly used Chinese medicine formulas for clearing heat and detoxifying. Quality control of the herbal complex like Chinese medicine formulas still remains a challenge. The successful approval of botanical drug Veregen by FDA indicated the importance of quantitative analysis in quality control of herbal medicines. In this study, an effective quantitative method based on conventional HPLC-DAD was developed for simultaneous determination of fourteen major ingredients (seven alkaloids, four flavonoids, three terpenes) in HLJDT. The established method was well validated in terms of linearity, sensitivity, precision, accuracy and stability and then successfully applied to quality evaluation of commercial HLJDT samples. The developed method can quantitatively determine up to 70% of the chemicals of commercial HLJDT sample and effectively revealed the significant variation in the quality of the commercial HLJDT samples collected from different locations. PMID:23973454

Kwok, Ka-Yan; Xu, Jun; Ho, Hing-Man; Chen, Hu-Biao; Li, Min; Lang, Yan; Han, Quan-Bin

2013-08-05

179

Examining the phase transition behavior of amphiphilic lipids in solution using statistical temperature molecular dynamics and replica-exchange Wang-Landau methods  

NASA Astrophysics Data System (ADS)

Two different techniques - replica-exchange Wang-Landau (REWL) and statistical temperature molecular dynamics (STMD) - were applied to systematically study the phase transition behavior of self-assembling lipids as a function of temperature using an off-lattice lipid model. Both methods allow the direct calculation of the density of states with improved efficiency compared to the original Wang-Landau method. A 3-segment model of amphiphilic lipids solvated in water has been studied with varied particle interaction energies (?) and lipid concentrations. The phase behavior of the lipid molecules with respect to bilayer formation has been characterized through the calculation of the heat capacity as a function of temperature, in addition to various order parameters and general visual inspection. The simulations conducted by both methods can go to very low temperatures with the whole system exhibiting well-ordered structures. With optimized parameters, several bilayer phases are observed within the temperature range studied, including gel phase bilayers with frozen water, mixed water (i.e., frozen and liquid water), and liquid water, and a more fluid bilayer with liquid water. The results obtained from both methods, STMD and REWL, are consistently in excellent agreement with each other, thereby validating both the methods and the results.

Gai, Lili; Vogel, Thomas; Maerzke, Katie A.; Iacovella, Christopher R.; Landau, David P.; Cummings, Peter T.; McCabe, Clare

2013-08-01

180

Rapid and global detection and characterization of aconitum alkaloids in Yin Chen Si Ni Tang, a traditional Chinese medical formula, by ultra performance liquid chromatography–high resolution mass spectrometry and automated data analysis  

Microsoft Academic Search

An improved method employing Metabolynx XS with mass defect filter (MDF), a post-acquisition data processing software, was developed and applied for global detection of aconitum alkaloids in Yin Chen Si Ni Tang, a traditional Chinese medical formula (TCMF). The full-scan LC–MS\\/MS data sets with extra mass were acquired using ultra performance liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry (UPLC\\/Q-TOF-MS) with

Guangli Yan; Hui Sun; Wenjun Sun; Li Zhao; Xiangcai Meng; Xijun Wang

2010-01-01

181

Comment on "Displacement along the Karakoram fault, NW Himalaya, estimated from LA-ICP-MS U–Pb dating of offset geologic markers" published by Shifeng Wang et al. in EPSL, 2012  

NASA Astrophysics Data System (ADS)

Field evidence for syn-deformation migmatization and crystallization along the Karakorum fault contradicts the study of Wang et al. (2012). The ages of such magmatic rocks provide minimum ages for the onset of deformation at ˜23 Ma in North Ayilari and ˜19 Ma in Tangtse. The onset of deformation at 12 Ma in the Ayilari range inferred by Wang et al. (2012) from a muscovite Ar/Ar age is a cooling age, thus only a minimum age. The ˜60 Ma granodiorite bodies, the ophiolitic rocks and the south Kailash thrust that are correlated across the fault to provide a 52±2 km finite offset do not define reliable piercing points. Such observations as well as our previous work concur to show that the Karakorum fault initiated in the Oligo-Miocene, and has a long-term dextral slip-rate between 7.5 and 13 mm/yr, approximately twice that proposed by Wang et al. (2012).

Leloup, P. H.; Weinberg, R. F.; Mukherjee, B. K.; Tapponnier, P.; Lacassin, R.; Boutonnet, E.; Chevalier, M.-L.; Valli, F.; Li, H.; Arnaud, N.; Paquette, J.-L.

2013-02-01

182

Qualitative and quantitative analysis of nine major compounds in the Bozhougyiqi-Tang using a high-performance liquid chromatography coupled with a diode array detector and electrospray ionization mass spectrometer  

PubMed Central

Background: Bozhougyiqi-Tang (BZYQT) is of traditional herbal medicine used for enhancement of digestive capacity. Objective: An accurate and reliable simultaneous determination using a HPLC-DAD and ESI-MS was developed and validated for the qualitative and quantitative analysis of 9 major compounds, ferulic acid (1), naringin (2), hesperidin (3), decursinol (4), glycyrrhizin (5), saikosaponin A (6), 6-gingerol (7), ginsenoside Rg3 (8), decursin (9), in traditional herbal medicine ‘Bozhougyiqi-Tang.’ Materials and Methods: The chromatographic separation of 9 compounds was performed on a SHISEIDO C18 column (250 mm × 4.6 mm i.d., S-5 ?m) using gradient elution with 0.1% trifluoroacetic acid and acetonitrile at a flow rate of 1.0 ml/min. The 9 compounds were identified based on peak retention time and UV spectrum and MS data of these compounds. Results: This developed method showed good linearity (R2 > 0.999). The LOD and LOQ of the major compounds were less than 0.09 and 0.28 ?g/ml, respectively. The intra - day and inter - day RSD values were within 2.06% and 1.64%, respectively. The mean recoveries were from 92.10% to 108.56% with less than 1.88%. The results indicated that established method had good precision and accuracy. Conclusion: The new method was successfully applied to the simultaneous analysis of 9 compounds in Bozhougyiqi-Tangs samples.

Weon, Jin Bae; Ma, Jin Yeul; Yang, Hye Jin; Lee, Bohyoung; Yun, Bo-Ra; Ma, Choong Je

2013-01-01

183

A water extract of Samchulkunbi-tang attenuates airway inflammation by inhibiting inos and MMP-9 activities in an ovalbumin-induced murine asthma model  

PubMed Central

Background In this study, we investigated the effect of Samchulkunbi-tang water extract (SCTE) in an established mouse model of ovalbumin (OVA)-induced allergic asthma. The effects of SCTE on the production of Th1 and Th2 cytokines, eotaxin, and total and OVA-specific immunoglobulin E, inducible nitric oxide synthase expression, and matrix metalloproteinase-9 activity were measured. Methods Mice were sensitized on days 0 and 14 with an intraperitoneal injection of 20 ?g ovalbumin (OVA) emulsified in 2 mg aluminum hydroxide in 200 ?L PBS buffer. On days 21, 22, and 23, mice received an airway exposure to OVA (1%, w/v, in PBS) for 1 h. SCTE was administered orally to mice at doses of 200 and 400 mg/kg per day from days 18 to 23. Results SCTE reduced the number of inflammatory cells, cytokines, and chemokines in bronchoalveolar lavage fluids and iNOS expression and MMP-9 activity in mouse lung tissue. Histological studies using hematoxylin & eosin and periodic acid-schiff staining showed that SCTE substantially inhibited OVA-induced inflammatory cell infiltration in lung tissue and goblet cell hyperplasia in the airway. SCTE also reduced IL-4 and IL-13 expression in concanavalin-A-stimulated splenocytes. These results were similar to those obtained with montelukast as a positive control. Conclusions Collectively, these results suggest that SCTE may be an effective oral treatment for allergic airway inflammation by virtue of its anti-inflammatory activity.

2012-01-01

184

Quasi-MSn identification of flavanone 7-glycoside isomers in Da Chengqi Tang by high performance liquid chromatography-tandem mass spectrometry  

PubMed Central

Background Da Chengqi Tang (DCT) is a common purgative formula in Chinese medicine. Flavanones are its major active compounds derived from Fructus Aurantii Immaturus. The present study developed an LC-MS/MS method to characterize two pairs of flavanone 7-glycoside isomers, i.e., hesperidin versus neohesperidin and naringin versus isonaringin. Methods After solid phase purification, components in sample were separated on a Agilent zorbax SB-C18 (5 ?m, 250 mm × 4.6 mm) analytical column. ESI-MS and quasi-MSn were performed in negative ion mode to obtain structural data of these two pairs of flavanone 7-glycoside isomers. Moreover, UV absorption was measured. Results There was no intra-pairs difference in the UV-Vis and MS/MS spectra of the two pairs of 7-glycoside isomers, whereas the mass spectrometry fragmentation pathways between pairs were different. Conclusion The present study developed a LC-MS/MS method to explore the inter- and intra-pair difference of two pairs of flavanone 7-glycoside isomers.

Xu, Fengguo; Liu, Ying; Zhang, Zunjian; Yang, Cheng; Tian, Yuan

2009-01-01

185

Huang-lian-jie-du-tang protects rats from cardiac damages induced by metabolic disorder by improving inflammation-mediated insulin resistance.  

PubMed

Huang-lian-jie-du-tang (HLJDT), a traditional Chinese medicine, has been shown to improve insulin resistance (IR) induced by inflammation, a key event in the development of metabolic syndrome (MS). The present study aimed to investigate the protective effects of HLJDT on MS and explore the underlying mechanism. MS rats were established with obese-diets and treated with normal saline, aspirin or HLJDT. The myocardial lesions were identified by echocardiogram, transmission electron microscope, and Sirius-red staining. The inflammatory cytokines were measured by ELISA and real-time PCR. The activation of NF-?B, JNK, SOCS3, IRS1 and AKT in the heart was detected by immunohistochemistry and Western blot analysis. Compared with the controls, MS rats developed obvious obesity, hypertension, dyslipidemia, IR, inflammation, and cardiac damage. Moreover, phosphorylated IRS-1 at Ser307 was correlated with the activation of NF-?B, JNK and SOCS3 and the inhibition of AKT in the heart from MS rats. These data suggest that serine phosphorylation of IRS-1 in response to inflammation is mediated, in part, by NF-?B, JNK and SOCS3. Notably, HLJDT inhibited the activation of NF-?B and reduced serine phosphorylation of IRS-1. In summary, HLJDT protects myocardium from IR-mediated injury by inhibiting serine phosphorylation of IRS-1 in MS rats. PMID:23840732

Li, Chuan Bao; Li, Xiao Xing; Chen, Yu Guo; Gao, Hai Qing; Bu, Pei Li; Zhang, Yun; Ji, Xiao Ping

2013-06-28

186

Metabolism and pharmacokinetics of san-huang-xie-xin-tang, a polyphenol-rich chinese medicine formula, in rats and ex-vivo antioxidant activity.  

PubMed

San-Huang-Xie-Xin-Tang (SHXXT), a widely used Chinese herbal formula, consists of rhizomes of Rheum officinale, roots of Scutellaria baicalensis and rhizomes of Coptis chinesis. This study investigated the metabolism and pharmacokinetics of polyphenols in SHXXT, including baicalin, baicalein, wogonin, emodin, aloe-emodin, rhein and chrysophanol. The quantitation methods of SHXXT decoction and rat serum using high performance liquid chromatography were developed and validated in this study. After oral administration of SHXXT decoction to rats, the parent forms of various constituents and their conjugated metabolites in serum were determined before and after hydrolysis with ?-glucuronidase and sulfatase. The results showed that only free form of rhein can be quantitated, whereas the parent forms of coptisine, palmatine, berberine, baicalein, wogonin, emodin, aloe-emodin and chrysophanol were not detected in serum. The glucuronides of baicalein, wogonin, emodin, aloe-emodin, rhein and chrysophanol were the predominant forms in bloodstream. In order to evaluate the in vivo antioxidant activity of SHXXT, the serum metabolite of SHXXT was prepared, characterized and followed by evaluation of the effect on AAPH-induced hemolysis. The results indicated that metabolites of SHXXT exhibited significant free radical scavenging activity. We suggest that biologists redirect their focus to the bioactivity of the conjugated metabolites of these polyphenols. PMID:19737807

Shia, Chi-Sheng; Hou, Yu-Chi; Juang, Shin-Hun; Tsai, Shang-Yuan; Hsieh, Pei-Hsun; Ho, Lu-Ching; Chao, Pei-Dawn Lee

2011-06-07

187

Metabolism and Pharmacokinetics of San-Huang-Xie-Xin-Tang, a Polyphenol-Rich Chinese Medicine Formula, in Rats and Ex-Vivo Antioxidant Activity  

PubMed Central

San-Huang-Xie-Xin-Tang (SHXXT), a widely used Chinese herbal formula, consists of rhizomes of Rheum officinale, roots of Scutellaria baicalensis and rhizomes of Coptis chinesis. This study investigated the metabolism and pharmacokinetics of polyphenols in SHXXT, including baicalin, baicalein, wogonin, emodin, aloe-emodin, rhein and chrysophanol. The quantitation methods of SHXXT decoction and rat serum using high performance liquid chromatography were developed and validated in this study. After oral administration of SHXXT decoction to rats, the parent forms of various constituents and their conjugated metabolites in serum were determined before and after hydrolysis with ?-glucuronidase and sulfatase. The results showed that only free form of rhein can be quantitated, whereas the parent forms of coptisine, palmatine, berberine, baicalein, wogonin, emodin, aloe-emodin and chrysophanol were not detected in serum. The glucuronides of baicalein, wogonin, emodin, aloe-emodin, rhein and chrysophanol were the predominant forms in bloodstream. In order to evaluate the in vivo antioxidant activity of SHXXT, the serum metabolite of SHXXT was prepared, characterized and followed by evaluation of the effect on AAPH-induced hemolysis. The results indicated that metabolites of SHXXT exhibited significant free radical scavenging activity. We suggest that biologists redirect their focus to the bioactivity of the conjugated metabolites of these polyphenols.

Shia, Chi-Sheng; Hou, Yu-Chi; Juang, Shin-Hun; Tsai, Shang-Yuan; Hsieh, Pei-Hsun; Ho, Lu-Ching; Chao, Pei-Dawn Lee

2011-01-01

188

Neuroprotective Effects of San-Huang-Xie-Xin-Tang in the MPP+/MPTP Models of Parkinson's Disease In Vitro and In Vivo  

PubMed Central

San-Huang-Xie-Xin-Tang (SHXT), composed of Coptidis rhizoma, Scutellariae radix, and Rhei rhizoma, is a traditional Chinese medicine used for complementary and alternative therapy of cardiovascular and neurodegenerative diseases via its anti-inflammatory and antioxidative effects. The aim of this study is to investigate the protective effects of SHXT in the 1–methyl–4–phenylpyridinium (MPP+)/1–methyl–4–phenyl–1,2,3,6–tetrahydropyridine (MPTP) models of Parkinson's disease. Rat primary mesencephalic neurons and mouse Parkinson disease model were used in this study. Oxidative stress was induced by MPP+ in vitro and MPTP in vivo. In MPP+-treated mesencephalic neuron cultures, SHXT significantly increased the numbers of TH-positive neurons. SHXT reduced apoptotic signals (cytochrome and caspase) and apoptotic death. MPP+-induced gp91phox activation and ROS production were attenuated by SHXT. In addition, SHXT increased the levels of GSH and SOD in MPP+-treated neurons. In MPTP animal model, SHXT markedly increased TH-positive neurons in the substantia nigra pars compacta (SNpc) and improved motor activity of mice. In conclusion, the present results reveal the evidence that SHXT possesses beneficial protection against MPTP-induced neurotoxicity in this model of Parkinson's disease via its antioxidative and antiapoptotic effects. SHXT might be a potentially alternative and complementary medicine for neuroprotection.

Lo, Yi-Ching; Shih, Yu-Tzu; Tseng, Yu-Ting; Hsu, Hung-Te

2012-01-01

189

Preventive effects of a traditional Chinese formulation, Chaihu-jia-Longgu-Muli-tang, on intimal thickening of carotid artery injured by balloon endothelial denudation in rats.  

PubMed

We report here that the traditional Chinese formulation, Chaihu-jia-Longgu-Muli-tang (CLM), significantly inhibited the increase in intimal thickening in rat carotid artery injured by balloon endothelial denudation, which mimics many aspects of restenosis after percutaneous coronary intervention (PCI) in humans. CLM, Saiko-ka-Ryukotsu-Borei-to in Japanese, is commonly prescribed for symptoms accompanying hypertension and atherosclerosis in Japanese Kampo medical care. CLM administered orally 1 week before and 1, 4 and 8 weeks after balloon injury inhibited the increase in intimal area, intimal/medial ratio and stenosis ratio. To our knowledge, this is the first report demonstrating inhibitory effects of a traditional Chinese formulation on intimal thickening of carotid artery after balloon injury. It is worth noting that CLM maintained its inhibitory effect up to 8 weeks after balloon injury. The reduction in intimal thickening by CLM could have resulted from inhibition of intimal smooth muscle cell proliferation, which was assessed by immuno-histochemical analysis using monoclonal antibody against proliferating cell nuclear antigen. Therefore, CLM may be a favourable candidate for prevention of restenosis after PCI. Moreover CLM may have a therapeutic value in the prevention of atherosclerosis, because restenosis after PCI is considered to be an accelerated atherosclerosis. PMID:11999136

Kim, Dong-Wook; Chung, Hwa-Jin; Nose, Katsuya; Maruyama, Ikuro; Tani, Tadato

2002-04-01

190

Inhibitory effect of Sihoga-Yonggol-Moryo-Tang on matrix metalloproteinase-2 and -9 activities and invasiveness potential of hepatocellular carcinoma.  

PubMed

A Korean traditional herbal formulation, Sihoga-Yonggol-Moryo-Tang (SGYMT), is being used for the treatment of many diseases such as tumor, neuropsychiatric, and vascular disorders. The extracts prepared from SGYMT and its herbal ingredients were assayed for the inhibitory effects on tumor-specific matrix metalloproteinases-2 and -9 (MMP-2/9) activities using gelatin zymography. The results showed that SGYMT decreased the gelatinolytic activities of MMP-2 and -9, which were secreted from SK-Hep1 cells. The IC(50) values of SGYMT against these enzymes were 85 and 145 micrograms ml(-1), respectively. The cytotoxocities of SGYMT and its ingredients on human hepatocellular carcinoma (HCC) cell, SK-Hep1 cells, were very low (IC(50)>150 micrograms ml(-1)) as measured by the XTT assay method. The extract were then investigated the inhibitory effect on the invasion of SK-Hep1 cells using matrigel precoated transwell chambers. The results showed that SGYMT effectively inhibited the invasion of SK-Hep1 cells as compared with the control groups. In addition, among herbal ingredients of SGYMT, the bark of Cinnamomum cassia BLUME (Cinnamomi Cortex) and roots of Scutellaria baicalensis GEORGI (Scutelleria Radix) have shown significant inhibition against MMP-2 and -9 activity and invasion of SK-Hep1 cells. From these results, it was suggested that SGYMT could be used as potential anti-tumor agent. PMID:15225671

Ha, Ki-Tae; Kim, June-Ki; Kang, Sung-Koo; Kim, Dong-Wook; Lee, Young-Choon; Kim, Hyung-Min; Kim, Cheorl-Ho

2004-09-01

191

The Chinese Herbal Medicine Formula Sheng-Fei-Yu-Chuan-Tang Suppresses Th2 Responses and Increases IFN? in Dermatophagoides pteronyssinus Induced Chronic Asthmatic Mice  

PubMed Central

Sheng-Fei-Yu-Chuan-Tang (SFYCT), a traditional Chinese medicine formula consisting of 13 medicinal plants, has been used in the treatment of asthma. This study demonstrated the immunoregulatory effect of SFYCT on chronic allergic asthma using the Dermatophagoides-pteronyssinus- (Der p-) challenged chronic asthmatic murine model. SFYCT decreased the airway hyperresponseness (AHR), pulmonary inflammatory cell infiltration, and airway remodeling in Der p mice. SFYCT treatment decreased Der p-induced total IgE and Der-p-specific IgG1 but not IgG2a/2b Ab titer in serum of Der p mice. SFYCT also decreased Th2 cytokines, IL-4, IL-5, and IL-13, but increased IFN-? and IL-12 in the BALF of Der p mice. TGF-?1 and collagen production in the lung of mice were decreased by SFYCT. The mRNA expression of chemokine including Eotaxin, RANTES, and MCP-1 in the lung of Der p mice was decreased by SFYCT. In conclusion, the suppressed Der-p-induced airway inflammation, remodeling, and hyperresponseness in chronic asthma murine model are related to SFYCT inhibits Th2 responses, decreases chemokine expression and promotes IFN-? and IL-12 production. SFYCT could show Der-p-induced Th2 responses to Th1 responses by increasing IFN-? which is merit for clinical application on asthma patients.

Lin, Chia-Hung; Yeh, Ching-Hua; Lin, Li-Jen; Wang, Jen-Shu; Wang, Shulhn-Der; Kao, Shung-Te

2013-01-01

192

Efficacy and Safety of Taeeumjowi-tang in Obese Korean Adults: A Double-Blind, Randomized, and Placebo-Controlled Pilot Trial  

PubMed Central

Objective. The purpose of this study was to assess the efficacy and safety of Taeeumjowi-tang (TJ001) as well as to estimate obesity-related factors. Methods. This was a 12-week trial with 5 visits. A total of 102 participants of both genders were randomized to either TJ001 (n = 57) group or the placebo group (n = 55). Subjects were administered 7?g of either TJ001 or placebo 3 times a day. The primary outcome was a rate of subjects who lost 5% or more of initial weight. Secondary outcomes included anthropometric parameters, lipid profiles, and body fat composition. Results. The subject response rate of ?5% weight loss compared to baseline was similar in both groups, and no statistically significant difference was observed (P = 0.87). Changes in anthropometric parameters were greater during the first 4 weeks in the treatment group (P < 0.0001). There were no significant changes in both within groups and between groups for lipid profile and body fat composition. No adverse event was reported in either group. Conclusion. Although the difference between the groups regarding a rate of subjects who lost 5% or more of initial weight did not show statistical significance, TJ001 appears to be beneficial in safely controlling weight.

Nahmkoong, Won; Cheon, ChunHoo; Park, Jeong-Su; Shin, Yongcheol; Kim, Kyung-Soo; Go, Hoyeon; Song, Yun-Kyung; Ko, Seong-Gyu

2013-01-01

193

A comprehensive platform for quality control of botanical drugs (PhytomicsQC): a case study of Huangqin Tang (HQT) and PHY906  

PubMed Central

Background Establishing botanical extracts as globally-accepted polychemical medicines and a new paradigm for disease treatment, requires the development of high-level quality control metrics. Based on comprehensive chemical and biological fingerprints correlated with pharmacology, we propose a general approach called PhytomicsQC to botanical quality control. Methods Incorporating the state-of-the-art analytical methodologies, PhytomicsQC was employed in this study and included the use of liquid chromatography/mass spectrometry (LC/MS) for chemical characterization and chemical fingerprinting, differential cellular gene expression for bioresponse fingerprinting and animal pharmacology for in vivo validation. A statistical pattern comparison method, Phytomics Similarity Index (PSI), based on intensities and intensity ratios, was used to determine the similarity of the chemical and bioresponse fingerprints among different manufactured batches. Results Eighteen batch samples of Huangqin Tang (HQT) and its pharmaceutical grade version (PHY906) were analyzed using the PhytomicsQC platform analysis. Comparative analysis of the batch samples with a clinically tested standardized batch obtained values of PSI similarity between 0.67 and 0.99. Conclusion With rigorous quality control using analytically sensitive and comprehensive chemical and biological fingerprinting, botanical formulations manufactured under standardized manufacturing protocols can produce highly consistent batches of products.

2010-01-01

194

Involvement of the Cerebral Monoamine Neurotransmitters System in Antidepressant-Like Effects of a Chinese Herbal Decoction, Baihe Dihuang Tang, in Mice Model  

PubMed Central

Baihe Dihuang Tang (BDT) is a renowned Chinese herbal formula which is commonly used for treating patients with mental instability, absentmindedness, insomnia, deficient dysphoria, and other psychological diseases. These major symptoms closely associated with the depressive disorders. BDT was widely popular use for treating emotion-thought disorders for many years in China. In the present study, the antidepressant-like effect of BDT in mice was investigated by using the forced swim test (FST) and the tail suspension test (TST). The underlying mechanism was explored by determining the effect of BDT on the level of cerebral monoamine neurotransmitters. BDT (9 and 18?g/kg, p.o. for 14 days) administration significantly reduced the immobility time in both the FST and the TST without changing locomotion in the open field-test (OFT). Moreover, BDT treatment at the dose of 18?g/kg inhibited reserpine-induced ptosis. Meanwhile, BDT enhanced 5-HT and NA levels in mouse cerebrum as well as decreased the ratio of 5-HT compared to its metabolite, 5-HIAA, (turnover, 5-HIAA/5-HT) after TST. The results demonstrated that the antidepressant-like effect of BDT is mediated, at least partially, via the central monoaminergic neurotransmitter system.

Chen, Meng-Li; Gao, Jie; He, Xin-Rong; Chen, Qian

2012-01-01

195

Enhancement of anti-allergic effects mediated by the Kampo medicine Shoseiryuto (Xiao-Qing-Long-Tang in Chinese) with lysed Enterococcus faecalis FK-23 in mice.  

PubMed

Kampo is a traditional Japanese medicine originating from ancient Chinese medicine which included the administration of herbal prescription, lifestyle advice and acupuncture. Orally administered Kampo prescriptions are believed to be influenced by diet and intestinal microbiota. However, reports on the Kampo administration effects are still limited. Shoseiryuto (TJ-19), which has anti-allergic and anti-inflammatory properties, is a Kampo prescription used clinically for the treatment of allergic bronchial asthma. We examined whether Shoseiryuto administration is affected by a probiotic product, lysed Enterococcus faecalis FK-23 (LFK). BALB/c mice were sensitized with cedar pollen allergen, and the peritoneal accumulation of eosinophils was induced. During a sensitization period of 21 days, varying amounts of Shoseiryuto (and saline as a control) were administered to the mice. The accumulation of eosinophils was significantly reduced by 30 mg/day doses of Shoseiryuto but not by 3 or 9 mg/day doses. Similarly, 3 mg/day Shoseiryuto, 30 mg/day LFK, 3 mg/day of Shoseiryuto co-administered with 30 mg/day of LFK, and saline control were compared. A significant reduction in the accumulation of eosinophils was observed at 3 mg/day Shoseiryuto co-administered with 30 mg/day of LFK. These results suggest that Shoseiryuto-mediated anti-allergic effects are enhanced by the probiotic (LFK). Although not significant statistically, serum allergen-specific and total IgE levels in the treatment group exposed to the mixed agent (ie. Shoseiryuto and LFK) were generally lower than those receiving either one alone. The results indicate a synergistic effect of a Kampo medicine (Shoseiryuto, Xiao-Qing-Long-Tang in Chinese) and lysed Enterococcus faecalis FK-23 on allergic responses in mice. PMID:20527518

Shimada, Takashi; Kondoh, Masatoshi; Motonaga, Chie; Kitamura, Yoshihisa; Cheng, Lei; Shi, HaiBo; Enomoto, Tadao; Tsuruta, Daisuke; Ishii, Masamitsu; Kobayashi, Hiromi

2010-03-01

196

HPLC-MS/MS Analysis of a Traditional Chinese Medical Formulation of Bu-Yang-Huan-Wu-Tang and Its Pharmacokinetics after Oral Administration to Rats  

PubMed Central

Bu-yang-huan-wu-tang (BYHWT) is one of the most popular formulated traditional Chinese medicine prescriptions, and is widely for prevention of ischemic cardio-cerebral vascular diseases and stroke-induced disability. A specific high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) has been developed and validated for simultaneous quantification of the nine main bioactive components, i.e., astragaloside I, astragaloside II, astragaloside IV, formononetin, ononin, calycosin, calycosin-7-O-?-d-glucoside, ligustilide and paeoniflorin in rat plasma after oral administration of BYHWT extract. This method was applied to investigate the pharmacokinetics in conscious and freely moving rats. No significant matrix effects were observed. The overall analytical procedure was rapid and reproducible, which makes it suitable for quantitative analysis of a large number of samples. Among them, three astragalosides and four isoflavones in A. membranaceus, ligustilide in Radix Angelicae Sinensis and Rhizoma Ligustici Chuanxiong and paeoniflorin in Radix Paeoniae Rubra were identified. This developed method was then successfully applied to pharmacokinetic studies of the nine bioactive constituents after oral administration of BYHWT extracts in rats. The pharmacokinetic data demonstrated that astragaloside I, astragaloside II, astragaloside IV and ligustilide presented the phenomenon of double peaks. The other herbal ingredients of formononetin, ononin, calycosin, calycosin-7-O-?-d-glucoside and paeoniflorin appeared together in a single and plateau absorption phase. These phenomenona suggest that these components may have multiple absorption sites, regulation of enterohepatic circulation or the gastric emptying rate, or there is ingredient-ingredient interaction. These pharmacokinetic results provide a constructive contribution to better understand the absorption mechanism of BYHWT and to support additional clinical evaluation.

Shaw, Lee-Hsin; Lin, Lie-Chwen; Tsai, Tung-Hu

2012-01-01

197

San-Huang-Xie-Xin-Tang Protects against Activated Microglia- and 6-OHDA-Induced Toxicity in Neuronal SH-SY5Y Cells  

PubMed Central

San-Huang-Xie-Xin-Tang (SHXT), composed of Coptidis rhizoma, Scutellariae radix and Rhei rhizoma, is a traditional Chinese herbal medicine used to treat gastritis, gastric bleeding and peptic ulcers. This study investigated the neuroprotective effects of SHXT on microglia-mediated neurotoxicity using co-cultured lipopolysaccharide (LPS)-activated microglia-like BV-2 cells with neuroblastoma SH-SY5Y cells. Effects of SHXT on 6-hydroxydopamine (6-OHDA)-induced neurotoxicity were also examined in SH-SY5Y cells. Results indicated SHXT inhibited LPS-induced inflammation of BV-2 cells by downregulation of iNOS, NO, COX-2, PGE2, gp91phox, iROS, TNF-?, IL-1?, inhibition of I?B? degradation and upregulation of HO-1. In addition, SHXT increased cell viability and down regulated nNOS, COX-2 and gp91phox of SH-SY5Y cells co-cultured with LPS activated BV-2 cells. SHXT treatment increased cell viability and mitochondria membrane potential (MMP), decreased expression of nNOS, COX-2, gp91phox and iROS, and inhibited I?B? degradation in 6-OHDA-treated SH-SY5Y cells. SHXT also attenuated LPS activated BV-2 cells- and 6-OHDA-induced cell death in differentiated SH-SY5Y cells with db-cAMP. Furthermore, SHXT-inhibited nuclear translocation of p65 subunit of NF-?B in LPS treated BV-2 cells and 6-OHDA treated SH-SY5Y cells. In conclusion, SHXT showed protection from activated microglia- and 6-OHDA-induced neurotoxicity by attenuating inflammation and oxidative stress.

Shih, Yu-Tzu; Chen, Ing-Jun; Wu, Yang-Chang; Lo, Yi-Ching

2011-01-01

198

Anti-allergic effects of So-Cheong-Ryong-Tang, a traditional Korean herbal medicine, in an allergic rhinitis mouse model.  

PubMed

The herbal medicine, So-Cheong-Ryong-Tang (SCRT) has been empirically used for the treatment of allergic rhinitis for hundreds of years; however, its in vivo effects on allergic rhinitis have been rarely elucidated. We aimed to evaluate the anti-allergic effects of SCRT in an allergic rhinitis mouse model and to examine the underlying mechanism(s) of its anti-allergic effects. BALB/c mice were sensitized with ovalbumin (OVA) and alum and then challenged intranasally with OVA. SCRT (1 g/kg) was given to the treatment group, and multiple parameters of allergic responses were evaluated to determine the effects of SCRT on allergic rhinitis. SCRT reduced allergic symptoms, such as rubbing and sneezing, and eosinophil infiltration into the nasal mucosa. It also suppressed serum total IgE, OVA-specific IgE, and OVA-specific IgG1 levels and increased OVA-specific IgG2a level. SCRT significantly reduced expression of the Th2 cytokine, IL-4; however, the expression of IL-5, IFN-?, and IL-10 was unchanged in the nasal mucosa of the treatment group (by real-time RT-PCR). In splenocyte culture, levels of both IL-4 and IL-5 decreased, and IFN-? level increased in the treatment group; however, levels of IL-10 and TGF-? were unaffected by administration of SCRT. This study shows that SCRT induced anti-allergic effects by decreasing, locally and systemically, the Th2 cytokine IL-4, isotype switching to IgE, and eosinophilic infiltration into the nasal mucosa in an allergic rhinitis mouse model. Thus, SCRT might be considered a potential therapeutic agent in treating allergic rhinitis. PMID:22903755

Mo, Ji-Hun; Lee, Seung-Eun; Wee, Jee Hye; Lee, Ji-Eun; Rhee, Chae-Seo; Lee, Chul Hee; Kim, Dong-Young

2012-08-19

199

Protective effects of Saiko-ka-ryukotsu-borei-to (Chai-Hu-Jia-Long-Gu-Mu-Li-Tang) against atherosclerosis in Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits.  

PubMed

We investigated the protective effects of the traditional Japanese herbal medicine Saiko-ka-ryukotsu-borei-to (Chai-Hu-Jia-Long-Gu-Mu-Li-Tang in Chinese) (SRBT) against hypercholesterolemia and atherosclerotic lesions. We focused on atherosclerosis using female heterozygous Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits. The total plasma cholesterol levels increased for up to 12 weeks after beginning a diet containing 0.1% cholesterol and then reached a plateau of about 600 mg dl(-1). When SRBT was administered at a dose of 1.0 g kg(-1)per day for 24 weeks, total plasma cholesterol levels were significantly decreased after 20-24 weeks. On the other hand, pravastatin at a dose of 10 mg kg(-1)per day produced a significant decrease in total plasma cholesterol levels from 4 to 24 weeks (about 105-130 mg dl(-1)). Moreover, 1.0 g kg(-1)per day of SRBT significantly decreased plasma low density lipoprotein (LDL) cholesterol levels but did not change either very low density lipoprotein (VLDL), or high density lipoprotein (HDL) cholesterol levels. Animals that received pravastatin had significantly decreased LDL cholesterol levels and VLDL cholesterol levels after 8 weeks and at 24 weeks. We also examined the expression of apoB, E and LDL receptor mRNA levels in the liver at 24 weeks after beginning the administration of 1.0 g kg(-1)per day of SRBT. Both apoE and LDL receptor mRNA levels were significantly increased compared with those in rabbits receiving the 0.1% cholesterol diet. SRBT at a dose of 1.0 g kg(-1)per day significantly depressed the intimal surface area of the thoracic aortae involved with atheromatous plaques. The present results suggest that SRBT may protect against hypercholesterolemia and atheromatous lesions by affecting apoE and LDL receptor mRNA gene expression in the liver. PMID:11394941

Yoshie, F; Iizuka, A; Kubo, M; Komatsu, Y; Matsumoto, A; Itakura, H; Takeda, H; Matsumiya, T; Kondo, K

2001-05-01

200

Concentration and detection of SARS coronavirus in sewage from Xiao Tang Shan Hospital and the 309th Hospital of the Chinese People's Liberation Army.  

PubMed

A worldwide outbreak of severe acute respiratory syndrome (SARS) had been reported. Over 8439 SARS cases and 812 SARS-related deaths were reported to the World Health Organization from 32 countries around the world up to 5 July 2003. The mechanism of transmission of SARS-CoV has been limited only to close contacts with patients. Attention was focused on possible transmission by the sewage system because laboratory studies showed that patients excreted coronavirus RNA in their stools in Amoy Gardens in Hong Kong. To explore whether the stool of SARS patients or the sewage containing the stool of patients would transmit SARS-CoV or not, we used a style of electropositive filter media particle to concentrate the SARS-CoV from the sewage of two hospitals receiving SARS patients in Beijing, as well as cell culture, semi-nested RT-PCR and sequencing of genes to detect and identify the viruses from sewage. There was no live SARS-CoV detected in the sewage in these assays. The nucleic acid of SARS-CoV was found in the sewage before disinfection from both hospitals by PCR. After disinfection, SARS-CoV RNA could be detected from some samples from the 309th Hospital of the Chinese People's Liberation Army, but not from Xiao Tang Shan Hospital after disinfection. In this study, we found that the virus can survive for 14 days in sewage at 4 degrees C, 2 days at 20 degrees C, and its RNA can be detected for 8 days though the virus had been inactivated. In conclusion, this study demonstrates that the RNA of SARS-CoV could be detected from the concentrates of sewage of both hospitals receiving SARS patients before disinfection and occasionally after disinfection though there was no live SARS-CoV; thus much attention should be paid to the treatment of stools of patients and the sewage of hospitals receiving SARS patients. PMID:16312970

Wang, X W; Li, J; Guo, T; Zhen, B; Kong, Q; Yi, B; Li, Z; Song, N; Jin, M; Xiao, W; Zhu, X; Gu, C; Yin, J; Wei, W; Yao, W; Liu, C; Li, J; Ou, G; Wang, M; Fang, T; Wang, G; Qiu, Y; Wu, H; Chao, F; Li, J

2005-01-01

201

Longdan Xiegan Tang has immunomodulatory effects on CD4+CD25+ T cells and attenuates pathological signs in MRL/lpr mice.  

PubMed

Longdan Xiegan Tang (LXT) is a Chinese herbal medicine that is prescribed as an anti-inflammatory aid, a hepato-protectant, and an immunostimulant. In this study, we examined the biological effects of LXT administration in MRL/lpr mice. MRL/lpr mice provide a good model of systemic lupus erythematosus (SLE). These mice develop immunological disturbances and dysregulation in Th1 and Th2 cytokine production. Female mice were randomly separated into two groups. The experimental group received LXT (250 mg/kg/day, po) from 19 to 21 weeks of age. Splenic CD3+CD4+, CD3+CD8+, and CD4+CD25+ T cells were increased in the LXT-administered mice compared to MRL/lpr controls, and this was associated with splenomegaly. There was a marked reduction in IFN-gamma, TNF-alpha, anti-dsDNA antibody, and there were reduced IgG immune complex deposits in the glomeruli. LXT also restored kidney glutathione levels, thereby limiting the toxic effects of the inflammatory mediators iNOS and COX-2, which are overproduced in MRL/lpr mice. Two-dimensional gel electrophoresis was used to analyze proteome changes. LXT protected MRL/lpr mice against developing the lupus syndrome through up-regulation of phosphoglycerate kinase 1 and down-regulation of ferritin light chain 1, selenium-binding protein 2, and alpha-enolase. This study indicates that LXT at this dose and time course of administration was effective in reducing oxidative stress associated with disease progression in MRL/lpr mice. LXT could be useful as adjunctive therapy for reducing distress in SLE. PMID:20372809

Lee, Tzung-Yan; Chang, Hen-Hong

2010-05-01

202

Using UPLC-QTOF-MS to Analyze the Chemical Changes between Traditional and Dispensing Granule Decoctions of San-Ao-Tang.  

PubMed

In the present study, a chemical profiling approach based on ultra-performance liquid chromatography coupled with photodiode array detection and time-of-flight mass spectrometry (UPLC-PDA-TOF-MS) was proposed to rapidly evaluate the chemical consistency between traditional and dispensing granule decoctions of traditional medicine combinatorial formulae and validated using San-Ao-Tang (SAT) as a model combinatorial formula. SAT is an effective traditional Chinese medicine, which is usually used in treating asthma and other diseases of the respiratory system. Two decoctions were prepared: traditional decoction, which is a water extract of three mixed constituent herbs of SAT; and dispensing granule decoction, which is a mixed water extract of each individual herb of SAT. Batches of these two decoction samples were subjected to UPLC-PDA-TOF-MS analysis and the data sets of tR-m/z pairs, ion intensities and sample codes were processed with supervised orthogonal partial least squared discriminant analysis to holistically compare their differences. Once a clear classification trend was found in the score plot, further statistics were performed to generate points at the two ends of S, and the components that correlated to these ions were regarded as the most changed components during decoction of the combinatorial formula. The changed components were identified by comparing the mass/ultraviolet spectra and retention times with those of reference compounds and/or tentatively assigned by matching empirical molecular formulae with those of the known compounds published in the literature. Using the proposed approach, global chemical differences were found between traditional and dispensing granule decoctions, like ephedrine, pseudoephedrine, norpseudoephedrine, licorice saponine H2, licorice saponine G2 and amygdalin. PMID:23572319

Ma, Chunhua; Qian, Yefei; Fan, Xinsheng; Shang, Erxin; Yao, Xin; Ma, Shiping

2013-04-01

203

Teng-Long-Bu-Zhong-Tang, a Chinese herbal formula, enhances anticancer effects of 5 - Fluorouracil in CT26 colon carcinoma  

PubMed Central

Background Colorectal cancer remains one of the leading causes of cancer death worldwide. Traditional Chinese Medicine (TCM) has played a positive role in colorectal cancer treatment. There is a great need to establish effective herbal formula for colorectal cancer treatment. Based on TCM principles and clinical practices, we have established an eight herbs composed formula for colorectal cancer treatment, which is Teng-Long-Bu-Zhong-Tang (TLBZT). We have demonstrated the anticancer effects of TLBZT against colorectal carcinoma in vitro. In present study, we evaluated the anticancer potential of TLBZT, used alone or in combination with low dose of 5-Fluorouracil (5-Fu), in CT26 colon carcinoma in vivo. Methods CT26 colon carcinoma was established in BALB/c mice and treated with TLBZT, 5-Fu, or TLBZT plus 5-Fu. The tumor volumes were observed. Apoptosis was detected by TUNEL assay. Caspases activities were detected by colorimetric assay. Cell senescence was indentified by senescence ?-galactosidase staining. Gene expression and angiogenesis was observed by immunohistochemistry or western blot. Results TLBZT significantly inhibited CT26 colon carcinoma growth. TLBZT elicited apoptosis in CT26 colon carcinoma, accompanied by Caspase-3, 8, and 9 activation and PARP cleavage, and downregulation of XIAP and Survivin. TLBZT also induced cell senescence in CT26 colon carcinoma, with concomitant upregulation of p16 and p21 and downregulation of RB phosphorylation. In addition, angiogenesis and VEGF expression in CT26 colon carcinoma was significantly inhibited by TLBZT treatment. Furthermore, TLBZT significantly enhanced anticancer effects of 5-Fu in CT26 colon carcinoma. Conclusions TLBZT exhibited significantly anticancer effect, and enhanced the effects of 5-Fu in CT26 colon carcinoma, which may correlate with induction of apoptosis and cell senescence, and angiogenesis inhibition. The present study provides new insight into TCM approaches for colon cancer treatment that are worth of further study.

2013-01-01

204

San-Huang-Xie-Xin-Tang Prevents Rat Hearts from Ischemia/Reperfusion-Induced Apoptosis through eNOS and MAPK Pathways  

PubMed Central

San-Huang-Xie-Xin-Tang (SHXT) is a traditional Chinese medication consisting of three herbs, namely Coptidis rhizome, Scutellariae radix and Rhei rhizome. This study aimed to examine the cardioprotective effects of SHXT in a rat model of acute myocardial apoptosis induced by ischemia/reperfusion (I/R). Vehicle (intravenous saline) or SHXT (intravenous or oral) was administered prior to I/R (occlusion of left coronary artery for 45?min followed by reperfusion for 2?h). In the vehicle group, myocardial I/R caused myocardial infarction with increased plasma cardiac enzymes, severe arrhythmia and mortality. Myocardial apoptosis was induced by I/R as evidenced by DNA ladder and Bcl-2/Bax ratio. In the SHXT group, we found that SHXT significantly reduced plasma levels of cardiac enzymes, arrhythmia scores (from 5 ± 1 to 2 ± 1, P < .01) and mortality rate (from 53 to 0%, P < .01). In addition, pretreatment with intravenous SHXT reduced the infarct size dose-dependently when compared with the vehicle group (10?mg?kg?1: 14.0 ± 0.2 versus 44.5 ± 5.0%, and 30?mg?kg?1: 6.2 ± 1.2% versus 44.5 ± 5.0%, both P < .01). Similarly, oral administration of SHXT reduced the infarct size dose-dependently. Furthermore, SHXT markedly decreased the apoptosis induced by I/R with increased Bcl-2/Bax ratio. Finally, we found that SHXT counteracted the I/R-induced downstream signaling, resulting in increased myocardial eNOS expression and plasma nitrite, and decreased activation of ERK1/2, p38 and JNK. These data suggest that SHXT has cardioprotective effects against I/R-induced apoptosis, and that these effects are mediated, at least in part, by eNOS and MAPK pathways.

Liou, Shu-Fen; Ke, Hung-Jen; Hsu, Jong-Hau; Liang, Jyh-Chong; Lin, Hung-Hong; Chen, Ing-Jun; Yeh, Jwu-Lai

2011-01-01

205

Simultaneous Determination of Dihydromyricetin and Resveratrol in Ampelopsis sinica (Miq.) W.T. Wang by High-Performance Liquid Chromatography Coupled with a Diode Array Detection Method.  

PubMed

Yeputaoteng is the dried ground part of Ampelopsis sinica (Miq.) W.T. Wang, which is widely used in traditional Chinese medicine for preventing and treating tumors, chronic nephritis, hepatitis, rubella, traumatic bleeding, stomach heat and vomiting. A simple and reliable method using high-performance liquid chromatography with diode array detection (HPLC-DAD) was developed for the simultaneous determination of dihydromyricetin and resveratrol in Yeputaoteng. The chromatographic analysis was performed on a Dikma C18 column (250 × 4.6 mm, 5 µm) at 30°C with a gradient elution of acetonitrile and 0.1% phosphoric acid at a flow rate of 1 mL/min, and used ultraviolet detection at 292 and 306 nm. The established method was validated in terms of linearity, precision, reproducibility, stability and recovery. The calibration curves showed good linear regression (R(2) > 0.9994). Limits of detection and quantification fell in the ranges of 1.47-2.48 and 2.93-4.97 µg/mL, respectively. The mean recovery of dihydromyricetin and resveratrol was 104.1% [relative standard deviation (RSD): 2.94%] and 100.8% (RSD: 2.80%), respectively. The quantitative results indicated that the HPLC-DAD method can be effectively applied to the quality control of Yeputaoteng and its preparations. PMID:23616429

Jin, Min-Yi; Ding, Yue; Zhang, Tong; Cai, Zhen-Zhen; Tao, Jian-Sheng

2013-04-24

206

High-performance purification of quaternary alkaloids from Corydalis yanhusuo W. T. Wang using a new polar-copolymerized stationary phase.  

PubMed

An efficient method for purification of alkaloids from Corydalis yanhusuo W. T. Wang using HPLC was developed, featuring a polar-copolymerized stationary phase named C18HCE. As ionizable solutes, the crude alkaloid sample often suffered from serious peak tailing problem on conventional RP-LC columns, and the separation would rapidly became destroyed with the increasing of load amount. However, on the new stationary phase, good peak shapes (asymmetry factor <1.5) as well as good loadability were easily obtained in a commonly used acidic mobile phase condition. The loading amount could reach 10 mg per injection on an analytical C18HCE column for laboratory-scale purification. About 6.8 mg of palmatine (HPLC purity >98%) and 44.4 mg of dehydrocorydaline (HPLC purity >98%) were rapidly derived from 200 mg of the crude alkaloid sample, and the recoveries of these two compounds were 76.5 and 81.7%, respectively. The purified alkaloids were characterized by comparing retention times with standard compounds as well as (1)H-NMR data. The new method is simple and high yielding, and it may provide a promising tool for purification of alkaloids as well as other alkaline compounds. PMID:21171176

Wang, Chaoran; Guo, Zhimou; Zhang, Jing; Zeng, Jing; Zhang, Xiuli; Liang, Xinmiao

2010-12-03

207

A commonly used chinese herbal formula, shu-jing-hwo-shiee-tang, potentiates anticoagulant activity of warfarin in a rabbit model.  

PubMed

Background: Drug interactions between traditional Chinese herbal medicines and the anticoagulant warfarin may cause patient harm and are, therefore, important in clinical practice. Our experience in daily practice suggests that prothrombin time (PT) is prolonged when warfarin is used in combination with the Chinese herbal formula Shu-Jing-Hwo-Shiee-Tang (SJHST) commonly used by patients with osteoarthritis. Objective: We conducted animal experiments to confirm the effect of SJHST and warfarin on anticoagulant activity. Methods: Forty-eight male New Zealand white rabbits were randomized into eight groups of six rabbits. Group A (Control group) was administered normal saline. Group B (Western Medicine group) was administered warfarin 1.5 mg/kg/day. Groups C, D, and E [Traditional Chinese Medicine (TCM) groups] were administered different doses of SJHST (0.5 mg/kg/day, 1 mg/kg/day, and 2 mg/kg/day, respectively). Groups F, G, and H (Combination Therapy groups) were administered warfarin 1.5 mg/kg/day and different doses of SJHST (0.5 mg/kg/day, 1 mg/kg/day, and 2 mg/kg/day, respectively). The total duration of treatment was 14 days. Blood samples were obtained prior to beginning the experiments (day 0) and on day 7, day 14, and day 17 (3 days after discontinuation of the medications). The activated partial thromboplastin time (APTT), PT, and thrombin time (TT) were calculated and compared among the different groups. Results: No significant changes were noted in APTT, PT or TT between the control and SJHST-only groups. Significant prolongations of APTT and PTT, but not TT, were observed in the combination groups compared to the warfarin-only group. The enhanced anticoagulant effects returned to normal three days after discontinuation of SJHST treatment. Conclusions: We confirmed that the Chinese herb SJHST enhances the anticoagulant effect of warfarin. Although the exact mechanisms of the interaction are unknown, physicians should be aware of the possibility of drug interactions between warfarin and Chinese herbal medicines owing to the increased risk of bleeding. PMID:24071980

Yang, Sien-Hung; Yu, Chia-Li; Chen, Hsing-Yu; Lin, Yi-Hsuan

2013-09-25

208

Screening and analysis of the multiple absorbed bioactive components and metabolites of Baihe Zhimu Tang by the metabolic fingerprinting technique and liquid chromatography/diode array detection-electrospray ionization-mass spectrometry  

PubMed Central

Background: Baihe Zhimu Tang (BZT) is a widely used traditional Chinese medicinal formula in treating various diseases; however, its active components have remained unknown. Materials and Methods: Based on the metabolic fingerprinting technique and liquid chromatography/diode array detection-electrospray ionization-mass spectrometry (LC/DAD-ESI-MS), a method for rapid screening and analysis of the multiple absorbed bioactive components and metabolites of an oral solution of Baihe Zhimu Tang (BZT) in rabbit plasma, urine and feces after oral administration of BZT was developed. Results: The results obtained from a comprehensive comparative analysis of the fingerprints of the BZT and its metabolic fingerprints in rabbit biological samples indicated that 19 components in the BZT were absorbed into the rabbit's body. Both of them were tentatively identified from their MS and UV spectra and retention behaviors by comparing the results with the reported literature. In addition, only six components were found in the metabolic fingerprints, which suggested that they might be metabolites of some components in the BZT. Conclusion: The findings demonstrated that the proposed method could be used to rapidly and simultaneously analyze and screen the multiple absorbed bioactive constituents and metabolites in a formula of traditional Chinese medicines (TCMs) by comparing and contrasting the chromatographic fingerprints with its metabolic fingerprints. This is very important not only for the pharmaceutical discovery process and the quality control of crude drugs, but also for explaining the curative mechanism of TCMs.

Qin, Kunming; Cai, Hao; Liu, Xiao; Lu, Tulin; Fang, Qianbo; Yao, Zhongqing; Xu, Zisheng; Cai, Baochang

2011-01-01

209

Walsh, Da Silva, and Wei Reply  

SciTech Connect

This is a reply to Stefano Sanvito and Chaitanya Das Pemmaraju's, Comment on Theoretical Description of Carrier Mediated Magnetism in Cobalt Doped ZnO, Phys. Rev. Lett. 102, 159701 (2009); and the original article is Theoretical Description of Carrier Mediated Magnetism in Cobalt Doped ZnO, Phys. Rev. Lett. 100, 256401 (2008).

Walsh, A.; Da Silva, J. L. F.; Wei, S. H.

2009-04-17

210

l-Tetrahydropalmatine, an Active Component of Corydalis yanhusuo W.T. Wang, Protects against Myocardial Ischaemia-Reperfusion Injury in Rats  

PubMed Central

l-Tetrahydropalmatine (l-THP) is an active ingredients of Corydalis yanhusuo W.T. Wang, which protects against acute global cerebral ischaemia-reperfusion injury. In this study, we show that l-THP is cardioprotective in myocardial ischaemia-reperfusion injury and examined the mechanism. Rats were treated with l-THP (0, 10, 20, 40 mg/kg b.w.) for 20 min before occlusion of the left anterior descending coronary artery and subjected to myocardial ischaemia-reperfusion (30 min/6 h). Compared with vehicle-treated animals, the infarct area/risk area (IA/RA) of l-THP (20, 40 mg/kg b.w.) treated rats was reduced, whilst l-THP (10 mg/kg b.w.) had no significant effect. Cardiac function was improved in l-THP-treated rats whilst plasma creatine kinase activity declined. Following treatment with l-THP (20 mg/kg b.w.), subunit of phosphatidylinositol 3-kinase p85, serine473 phosphorylation of Akt and serine1177 phosphorylation of endothelial NO synthase (eNOS) increased in myocardium, whilst expression of inducible NO synthase (iNOS) decreased. However, the expression of HIF-1? and VEGF were increased in I30 minR6 h, but decreased to normal level in I30 minR24 h, while treatment with l-THP (20 mg/kg b.w.) enhanced the levels of these two genes in I30 minR24 h. Production of NO in myocardium and plasma, activity of myeloperoxidase (MPO) in plasma and the expression of tumour necrosis factor-? (TNF-?) in myocardium were decreased by l-THP. TUNEL assay revealed that l-THP (20 mg/kg b.w.) reduced apoptosis in myocardium. Thus, we show that l-THP activates the PI3K/Akt/eNOS/NO pathway and increases expression of HIF-1? and VEGF, whilst depressing iNOS-derived NO production in myocardium. This effect may decrease the accumulation of inflammatory factors, including TNF-? and MPO, and lessen the extent of apoptosis, therefore contributing to the cardioprotective effects of l-THP in myocardial ischaemia-reperfusion injury.

Tang, Yan; Bai, Wenli; Yang, Fan; Xie, Liping; Li, Xiaozhen; Zhou, Suming; Pan, Shiyang; Chen, Qi; Ferro, Albert; Ji, Yong

2012-01-01

211

Improving Safety of the Blood Supply from Transmission of ...  

Center for Biologics Evaluation and Research (CBER)

... microarray assay. Zhao J, Tang S, Storhoff J, Marla S, Bao YP, Wang X, Wong EY, Ragupathy V, Ye Z, Hewlett IK. Anal Chem ... More results from www.fda.gov/biologicsbloodvaccines/scienceresearch/biologicsresearchareas

212

Suppression of transforming growth factor-beta1 gene expression by Danggui buxue tang, a traditional Chinese herbal preparation, in retarding the progress of renal damage in streptozotocin-induced diabetic rats.  

PubMed

Danggui buxue tang (DBT), a preparation containing Angelica sinensis (danggui) and Astragalus membranaceus (huangqi) at a ratio of 1 : 5, is used widely in China for stimulating red blood cell production and enhancing cardiovascular function. The present study was undertaken to characterize the effects of this preparation on diabetic nephropathy using streptozotocin-diabetic rats as a model. Streptozotocin-dependent alterations in renal weight/body weight ratio, urinary albumin and beta (2)-microglobulin concentrations, urinary albumin excretion rate, and creatinine clearance were ameliorated after eight weeks of treatment with either DBT or the angiotensin-converting enzyme inhibitor, benazepril. DBT, but not benazepril, partially attenuated the increases in blood glucose, triglycerides and cholesterol in STZ-diabetic rats. Additionally, the increased expression of transforming growth factor-beta (1) mRNA in the renal cortex due to streptozotocin-induced diabetes was modestly attenuated by these treatments. However, eight weeks of treatment with DBT failed to modify the concentration of angiotensin II in plasma or kidney, indicating that the ability of the preparation to retard the progression of kidney disease was not attributable to inhibition of the renin-angiotensin system. We propose that DBT alleviates renal alterations in diabetes and slows the progression of diabetic nephropathy by suppressing transforming growth factor-beta (1) mRNA expression. The preparation may therefore be useful as an adjuvant therapy for controlling diabetes and its complications. PMID:16523407

Zhang, Y W; Xie, D; Xia, B; Zhen, R T; Liu, I-M; Cheng, J-T

2006-02-01

213

Chan-Yu-Bao-Yuan-Tang, the water extract of a chinese medicine prescription, induces s-phase arrest and mitochondria-mediated apoptosis in human lung adenocarcinoma cells.  

PubMed

Previous clinical studies have shown good efficacy of the traditional Chinese medicinal herbal water extract Chan-Yu-Bao-Yuan-Tang (CYBYT) in lung cancer patients. In this study, CYBYT's effects on proliferation and apoptosis of human lung adenocarcinoma cell line SPC-A-1 cultured in vitro were explored. An XTT assay, cell cycle analysis, Annexin V-FITC staining and Western blot were applied to identify the viability of cells, cell cycle arrest, stages of apoptosis, and signaling proteins, respectively. The results showed that CYBYT inhibited the growth of SPC-A-1 cells by reducing the cells in G0/G1 phase but increasing them in S phase in a concentration-dependent manner, and inducing apoptosis, whereas it had no significant inhibitory effects on the normal human IMR-90 fibroblasts. Furthermore, early and total induction of apoptosis was positively correlated with the concentration of CYBYT in SPC-A-1 cells, and the rate of total apoptosis was greater in the CYBYT 100 µg/mL and 50 µg/mL groups than that of the positive control 5-fluorouracil (5-Fu) group. Moreover, CYBYT upregulated bax, cleaved caspase-3 protein expression, downregulated bcl-2 protein expression, and released mitochondrial cytochrome c into the cytosol in a time- and concentration-dependent manner. Our findings indicated that CYBYT could significantly inhibit growth and induce apoptosis via the mitochondrial pathway in human lung adenocarcinoma cell line SPC-A-1. PMID:21382962

Liu, XiaoGuang; Li, YunCheng; Zeng, Fang; Huang, YanYan; Zhou, JiHang; Wang, YeKai; Zhou, ShiQuan; Zhu, WangYu; Chen, Gang; Zhang, YongKui

2011-03-07

214

Proteomics study on the hepatoprotective effects of traditional Chinese medicine formulae Yin-Chen-Hao-Tang by a combination of two-dimensional polyacrylamide gel electrophoresis and matrix-assisted laser desorption/ionization-time of flight mass spectrometry.  

PubMed

Proteomics can bring breakthroughs in the study of traditional Chinese medicine (TCM). Yin-Chen-Hao-Tang (YCHT), a famous TCM formulae, has been used to alleviate various types of liver injury. However, the underlying mechanisms and drug targets of YCHT associated with the hepatic injury are largely unknown. To identify the possible target proteins of YCHT, two-dimensional gel electrophoresis (2-DE)-based proteomics was performed and proteins altered after YCHT treatment were identified by MALDI-TOF/TOF-MS. Interestingly, 15 modulated proteins were identified, out of which 7 were found to be significantly altered by YCHT. YCHT treatment caused a statistically significant down-regulation of zinc finger protein 407, haptoglobin, macroglobulin, alpha-1-antitrypsin; significant up-regulation of transthyretin, vitamin D-binding protein, and prothrombin, appear to be involved in metabolism, energy generation, chaperone, antioxidation, signal transduction, protein folding and apoptosis. Finally, interaction network from 7 differentially expressed protein to the signal-related proteins was established using bioinformatic analysis. Of note, these signal-related proteins could be included in a network together with 7 proteins through direct interaction or only one intermediate partner. Functional pathway analysis suggested that these proteins were closely related in the protein-protein interaction network and the modulation of multiple vital physiological pathways. Thus, our data will help to understand the molecular mechanisms of hepatoprotective effects of YCHT. PMID:23262417

Sun, Hui; Zhang, Aihua; Yan, Guangli; Han, Ying; Sun, Wenjun; Ye, Yuan; Wang, Xijun

2012-11-23

215

Xiang-Qi-Tang and its active components exhibit anti-inflammatory and anticoagulant properties by inhibiting MAPK and NF-?B signaling pathways in LPS-treated rat cardiac microvascular endothelial cells.  

PubMed

Xiang-Qi-Tang (XQT) is a Chinese herbal formula containing Cyperus rotundus, Astragalus membranaceus and Andrographis paniculata. Alpha-Cyperone (CYP), astragaloside IV (AS-IV) and andrographolide (AND) are the three major active components in this formula. XQT may modulate the inflammatory or coagulant responses. We therefore assessed the effects of XQT on lipopolysaccharide (LPS)-induced inflammatory model of rat cardiac microvascular endothelial cells (RCMECs). XQT, CYP, AS-IV and AND inhibited the production of tumor necrosis factor alpha (TNF-?), intercellular cell adhesion molecule-1 (ICAM-1) and plasminogen activator inhibitor-1 (PAI-1), and up-regulated the mRNA expression of Kruppel-like factor 2 (KLF2). XQT and CYP inhibited the secretion of tissue factor (TF). To further explore the mechanism, we found that XQT, or its active components CYP, AS-IV and AND significantly inhibited extracellular signal-regulated kinase (ERK), c-jun NH2-terminal kinase (JNK) and p38 phosphorylation protein expression as well as decreased the phosphorylation levels of nuclear factor ?B (NF-?B) p65 proteins in LPS-stimulated RCMECs. These results suggested that XQT and its active components inhibited the expression of inflammatory and coagulant mediators via mitogen-activated protein kinase (MAPKs) and NF-?B signaling pathways. These findings may contribute to future research on the action mechanisms of this formula, as well as therapy for inflammation- or coagulation-related diseases. PMID:23171279

He, Chang-Liang; Yi, Peng-Fei; Fan, Qiao-Jia; Shen, Hai-Qing; Jiang, Xiao-Lin; Qin, Qian-Qian; Song, Zhou; Zhang, Cui; Wu, Shuai-Cheng; Wei, Xu-Bin; Li, Ying-Lun; Fu, Ben-Dong

2012-11-21

216

A Chinese Herbal Decoction, Dang Gui Bu Xue Tang, Prepared from Radix Astragali and Radix Angelicae sinensis, Ameliorates Insulin Resistance Induced by A High-Fructose Diet in Rats.  

PubMed

Dang Gui Bu Xue Tang (DBT), a Chinese medicinal decoction contains Radix Angelicae sinensis (Danggui) and Radix Astragali (Huangqi) at a ratio of 1?:?5, is used commonly for treating women's ailments. This study was conducted to explore the effects of this preparation on insulin resistance in rats fed with 6-week diet containing 60% fructose. Similar to the action of rosiglitazone (4?mg?kg(-1) per day by an oral administration), repeated oral administration of DBT (2.5?g?kg(-1) per day) for 14 days was found to significantly alleviate the hyperglycemia but made no influence on plasma lipid profiles nor weight gain in fructose chow-fed rats. Also, the higher degree of insulin resistance as measured by homeostasis model assessment of basal insulin resistance in fructose chow-fed rats was significantly decreased by repeated DBT treatment. DBT displays the characteristic of rosiglitazone by increasing the whole-body insulin sensitivity in fructose chow-fed rats after 2-week treatment, as evidenced by the marked elevation of composite whole-body insulin sensitivity index during the oral glucose tolerance test. DBT improves insulin sensitivity through increased post-receptor insulin signaling mediated by enhancements in insulin receptor substrate-1-associated phosphatidylinositol 3-kinase step and glucose transporter subtype 4 translocation in soleus muscles of animals exhibiting insulin resistance. DBT is therefore proposed as potentially useful adjuvant therapy for patients with insulin resistance and/or the patients who wish to increase insulin sensitivity. PMID:19233878

Liu, I-Min; Tzeng, Thing-Fong; Liou, Shorong-Shii

2011-02-14

217

Huang-Lian-Jie-Du-Tang supplemented with Schisandra chinensis Baill. and Polygonatum odoratum Druce improved glucose tolerance by potentiating insulinotropic actions in islets in 90% pancreatectomized diabetic rats.  

PubMed

We investigated to determine what effects, if any, the respective water extracts of Radix scutellariae (RS), Fructus schisandrae chinensis (FSC), Huang-Lian-Jie-Du-Tang (HLJDT), and HLJDT supplemented with FSC, and Rhizoma Polygonati odorati (HLJDT-M) would have on glucose tolerance by modulating glucose-stimulated insulin secretion, beta-cell mass, and morphometry in 90% pancreatectomized (Px) diabetic rats fed high-fat diets. Through the elevation of intracellular cAMP levels, FSC RS, HLJDT, and HLJDT-M increased insulin secretion in Min6 cells and GLP-1 secretion in NCI-H716 cells. After an 8-week period of treatment, it was found that HLJDT-M improved glucose tolerance in an oral glucose tolerance test in Px rats. HLJDT-M also potentiated first- and second-phase insulin secretion, but RS and HLJDT elevated only the second phase at hyperglycemic clamp. RS and HLJDT increased beta-cell mass by hyperplasia and hypertrophy, while HLJDT-M increased it only by hyperplasia. The rise in hyperplasia was associated with elevated IRS2 and PDX-1 expression in the islets. In conclusion, HLJDT-M worked as an anti-diabetic prescription by enhancing insulinotropic actions in diabetic rats. PMID:19897925

Park, Sunmin; Hong, Sang Mee; Ahn, Il Sung; Kim, Yang Jin; Lee, Jung Bok

2009-11-07

218

Therapeutic Effect of Yi-Chi-Tsung-Ming-Tang on Amyloid ?1?40-Induced Alzheimer's Disease-Like Phenotype via an Increase of Acetylcholine and Decrease of Amyloid ?  

PubMed Central

Alzheimer's disease (AD) is an irreversible neurodegenerative disorder characterized by amyloid accumulation, neuronal death, and cognitive impairments. Yi-Chi-Tsung-Ming-Tang (YCTMT) is a traditional Chinese medicine and has never been used to enhance cognitive function and treat neurodegenerative disorders such as senile dementia. Whether YCTMT has a beneficial role in improving learning and memory in AD patients remains unclear. The present study showed that oral administration of YCTMT ameliorated amyloid-?- (A?1?40) injection-induced learning and memory impairments in rats, examined using passive avoidance and Morris water-maze tests. Immunostaining and Western Blot results showed that continuous A?1?40 infusion caused amyloid accumulation and decreased acetylcholine level in hippocampus. Oral administration of medium and high dose of YCTMT 7 days after the A?1?40 infusion decreased amyloid accumulation area and reversed acetylcholine decline in the A?1?40-injected hippocampus, suggesting that YCTMT might inhibit A? plague accumulation and rescue reduced acetylcholine expression. This study has provided evidence on the beneficial role of YCTMT in ameliorating amyloid-induced AD-like symptom, indicating that YCTMT may offer an alternative strategy for treating AD.

Yeh, Chung-Hsin; Hsieh, Ming-Tsuen; Hsueh, Chi-Mei; Wu, Chi-Rei; Huang, Yi-Chun; Liao, Jiunn-Wang; Chow, Kuan-Chih

2012-01-01

219

[History of hot spring bath treatment in China].  

PubMed

As early as the 7th century B.C. (Western Zhou Dynasty), there is a recording as 'spring which contains sulfur could treat disease' on the Wentang Stele written by WANG Bao. Wenquan Fu written by ZHANG Heng in the Easten Han Dynasty also mentioned hot spring bath treatment. The distribution of hot springs in China has been summarized by LI Daoyuan in the Northern Wei Dynasty in his Shuijingzhu which recorded hot springs in 41 places and interpreted the definition of hot spring. Bencao Shiyi (by CHEN Cangqi, Tang Dynasty) discussed the formation of and indications for hot springs. HU Zai in the Song Dynasty pointed out distinguishing hot springs according to water quality in his book Yuyin Conghua. TANG Shenwei in the Song Dynasty noted in Jingshi Zhenglei Beiji Bencao that hot spring bath treatment should be combined with diet. Shiwu Bencao (Ming Dynasty) classified hot springs into sulfur springs, arsenicum springs, cinnabar springs, aluminite springs, etc. and pointed out their individual indications. Geologists did not start the work on distribution and water quality analysis of hot springs until the first half of the 20th century. There are 972 hot springs in Wenquan Jiyao (written by geologist ZHANG Hongzhao and published in 1956). In July 1982, the First National Geothermal Conference was held and it reported that there were more than 2600 hot springs in China. Since the second half of the 20th century, hot spring sanatoriums and rehabilitation centers have been established, which promoted the development of hot spring bath treatment. PMID:22169492

Hao, Wanpeng; Wang, Xiaojun; Xiang, Yinghong; Gu Li, A Man; Li, Ming; Zhang, Xin

2011-07-01

220

Ssanghwa-tang, an oriental herbal cocktail, exerts anti-melanogenic activity by suppression of the p38 MAPK and PKA signaling pathways in B16F10 cells  

PubMed Central

Background Ssanghwa-tang (SHT) is a widely used medication for the treatment of fatigue, pain, inflammation, hypothermia, erectile dysfunction, cancer, and osteoporosis in Asia, however, role of SHT on the melanin synthesis has not been checked previously. Thus, the present study was designed to determine the effect of SHT on ?-melanocyte stimulating hormone (?-MSH)-induced melanogensis and its mechanisms of action in murine B16F10 melanoma cells. Method Cellular melanin content and tyrosinase activity in murine B16F10 melanoma cells were determined after ?-MSH stimulation with or without pre-treatment of SHT at the concentration of 250 and 500 ?g/ml. Expression level of tyrosinase, tyrosinase-related protein 1 (TRP-1), TRP-2, microphthalmia-associated transcription factor (MITF), and activation of c-AMP-dependent protein kinase (PKA), c-AMP-related element binding protein (CREB), and mitogen-activated protein kinases (MAPKs) were examined by Western blot analysis. Results SHT significantly inhibited ?-MSH-induced melanin synthesis and tyrosinase activity, and also decreased ?-MSH-induced expression of MITF, tyrosinase, and TRP-1. In addition, SHT remarkably suppressed tyrosinase, CRE, and MITF luciferase reporter activity in a resting state as well as in ?-MSH-stimulating condition. Phosphorylation of p38 MAPK by ?-MSH stimulation was efficiently blocked by SHT pre-treatment. Moreover, SHT as an herbal cocktail showed synergistic anti-melanogenic effect compared with that of each single constituent herb. Conclusion SHT efficiently inhibited c-AMP-induced melanin synthesis in B16F10 cells via suppression of PKA and p38 MAPK signaling pathways and subsequently decreased the level of CREB phosphorylation, MITF, and melanogenic enzymes. These results indicate that SHT may be useful as herbal medicine for treating hyperpigmentation and cosmetics as a skin-whitening agent.

2013-01-01

221

Inhibitory Effects of Hwangryunhaedok-Tang in 3T3-L1 Adipogenesis by Regulation of Raf/MEK1/ERK1/2 Pathway and PDK1/Akt Phosphorylation  

PubMed Central

Hwangryunhaedok-tang (HRT) has been long used as traditional medicine in Asia. However, inhibitory role of HRT is unclear in early stage of 3T3-L1 adipocyte differentiation related to signaling. In the present study, we investigated the inhibitory effects of HRT on upstream signaling of peroxisome proliferation-activity receptor-? (PPAR-?) and CCAAT/enhancer binding protein-? (C/EBP-?) expression in differentiation of 3T3-L1 preadipocytes. We found that HRT significantly inhibited the adipocyte differentiation by downregulating several adipocyte-specific transcription factors including PPAR-?, C/EBP-?, and C/EBP-? in 3T3-L1 preadipocytes. Furthermore, we observed that HRT markedly inhibited the differentiation media-mediated phosphorylation of Raf/extracellular mitogen-activated protein kinase 1 (MEK1)/signal-regulated protein kinase 1/2 (ERK1/2) and phosphorylation of phosphoinositide-dependent kinase 1 (PDK1)/Akt. These results indicate that anti-adipogenesis mechanism involves the downregulation of the major transcription factors of adipogenesis including PPAR-? and C/EBP-? through inhibition of Raf/MEK1/ERK1/2 phosphorylation and PDK1/Akt phosphorylation by HRT. Furthermore, high performance liquid chromatography (HPLC) analysis showed HRT contains active antiobesity constituents such as palmatine, berberine, geniposide, baicalin, baicalein, and wogonin. Taken together, this study suggested that anti-adipogenesis effects of HRT were accounted by downregulation of Raf/MEK1/ERK1/2 pathway and PDK1/Akt pathway during 3T3-L1 adipocyte differentiation.

Lee, Ji-Hye; Kim, Dong-Gun; Kim, Taesoo; Lee, Kwang Jin; Ma, Jin Yeul

2013-01-01

222

Metabolism and tissue distribution study of Vaccaria seeds (Wang-Bu-Liu-Xing) in benign prostatic hyperplasia model rat: Toward an in-depth study for its bioactive components.  

PubMed

Vaccaria seeds (Wang-Bu-Liu-Xing), a well-known traditional Chinese medicine (TCM), has been used as an emperor herb of many ancient formulas to treat benign prostatic hyperplasia (BPH) in clinic. However, its metabolism and tissue distribution, especially in the target tissue, had not been investigated so far. Based on the hypothesis that the components which exert effect against BPH of Vaccaria seeds would be measureable in target tissue (prostate), in vivo metabolism and tissue distribution of Vaccaria seeds in rats were profiled using a specific and sensitive high performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry (LC-QTOF-MS/MS). As a result, 19 major constituents in the Vaccaria seeds decoction and 19 constituents in rat plasma, feces and tissues after oral administration of Vaccaria seeds decoction were identified. Accurate mass measurement for molecular ions and characteristic fragment ions could represent reliable identification criteria for these compounds. Two prototypes were detected in prostate. An in vitro metabolism analysis of them was studied after incubation with rat intestinal flora and rat liver microsome (RLM) in this paper, which is helpful for further investigation of the potential effect of these two components. The result of this study provided meaningful information for further pharmacology research on Vaccaria seeds. PMID:23973757

Qi, Peng; Li, Zhixiong; Chen, Mingcang; Sun, Zhaolin; Huang, Chenggang

2013-08-07

223

Diversity of Stomoxys spp. (Diptera: Muscidae) and diurnal variations of activity of Stomoxys indicus and S. calcitrans in a farm, in Wang Nam Khiao District, Nakhon Ratchasima Province, Thailand.  

PubMed

A study of species diversity of Stomoxys spp. and diurnal variations of activity of the most abundant was performed during a one year period at a local dairy cattle farm in Wang Nam Khiao District, Nakhon Ratchasima Province, Thailand. Four species of stomoxyine flies were morphologically identified, including Stomoxys indicus Picard 1908, S. calcitrans (Linnaeus 1758), S. sitiens Rondani 1873 and S. uruma Shinonaga and Kanao 1966. The most common species were S. indicus (50.2%) and S. calcitrans (49.5%). S. sitiens and S. uruma were found in small proportions (< 1%). The number of flies captured was significantly different among the three seasons with the greatest number in the rainy season (mean = 66%; df = 2, P < 0.05). The variations of diurnal activity were observed during different period of times (06:00 to 18:00) during three seasons. Both sexes of S. indicus and males of S. calcitrans showed unimodal activity pattern in cool and summer seasons. But a bimodal activity pattern was recorded in rainy season. For females S. calcitrans, a unimodal peak of activity was observed in cool season and a constant variation of activity all along the day in summer and rainy seasons, with an increase from the morning to the evening. A better understanding of stomoxyine fly behavior, especially the daily flight activity, can assist in prioritization and design of appropriate vector prevention and control strategies. PMID:22910668

Keawrayup, S; Duvallet, G; Sukonthabhirom, S; Chareonviriyaphap, T

2012-08-01

224

Peer review statement  

NASA Astrophysics Data System (ADS)

All papers published in this volume of Journal of Physics: Conference Series have been peer reviewed through processes administered by the editors of the 26th IAHR Symposium on Hydraulic Machinery and Systems proceedings. Reviews were conducted by expert referees from the International Technical Committee to the professional and scientific standards expected of a proceedings journal published by IOP Publishing. The members of the Scientific Committee who selected and reviewed the papers included in the Proceedings of the 26th IAHR Symposium on Hydraulic Machinery and Systems are: Yulin WU Tsinghua University China François AVELLAN EPFL-LMH Switzerland (principal) Xingqi LUO Xi'an University of Sci & Tech China Martin BÖHLE Kaiserslautern University Germany Gerard BOIS Arts et Métiers ParisTech France Luca D'AGOSTINO University of Pisa Italy Eduard EGUSQUIZA Polytechnical University Catalonia Spain Richard FISHER Voith Hydro Inc USA Regiane FORTES-PATELLA Institute Polytechnique de Grenoble France Aleksandar GAJIC University of Belgrade Serbia Wei YANG China Agriculture University China YinLu YOUNG University of Michigan USA Adrian LUNGU Dunarea de Jos University of Galati Romania Arpad FAY University of Miskolcz Hungary José GONZÁLEZ Universidad de Oviedo Spain Baoshan ZHU Tsinghua University China Hongxun CHEN Shanghai University China Chisachi KATO University of Tokyo Japan Zhenyue MA Dalian University of Sci & Tech China Honggang FAN Tsinghua University China François GUIBAULT Ecole Polytechnique de Montreal Canada Pengcheng GUO Xian University of Technology China Leqing WANG Zhejiang University China Toshiaki IKOHAGI Tohoku University Japan Jiandong YANG Wuhan University China Jianzhong ZHOU Huazhong University of Sci & Tech China Jinwei LI NULL China Rennian LI Lanzhou University of Sci & Tech China Houlin LIU NULL China Juan LIU Tsinghua University China Shuhong LIU Tsinghua University China Xianwu LUO Tsinghua University China Michihiro NISHI Tsinghua University China Peter PELZ Darmstadt University Germany František POCHYLY Brno University Czech Republic Rudolf SCHILLING Technische Universität München Germany Minguan YANG Jiangsu University China Smaine KOUIDRI Université Pierre et Marie Curie (Paris 6) France Kazuhiro TANAKA Kyushu Institute of Technology Japan Xuelin TANG Tsinghua University China Yoshinobu TSUJIMOTO Osaka University Japan Fujun WANG China Agriculture University China Guoyu WANG Beijing University of Sci & Tech China Wenwu SONG NULL China Zhengwei WANG Tsinghua University China Hongyuan XU Tsinghua University China Lefu XIAO NULL China Fan YANG Tsinghua University China Yuan ZHENG Hehai University China Zhigang ZUO Tsinghua University China Hongwu ZHU China Petroleum University China Lixiang ZHANG Yunnan University of Sci & Tech China Shengchang ZHANG Zhejiang University of Tech China

2012-11-01

225

Les mémoires de la dynastie Tang  

NASA Astrophysics Data System (ADS)

Dans la nuit des temps, les astronomes chinois ont ete d'incomparables observateurs de cometes. Ces savants, dont les notations raffinees ponctuaient l'histoire officielle des empereurs, relevaient chaque passage d'astre errant avec une precision inestimable. Un veritable tresor ou puise encore la science contemporaine.

Bonnet-Bidaud, J. M.

1996-07-01

226

Interpretation of Fractions in Quantum Hall Effect: Wei Pan's data  

NASA Astrophysics Data System (ADS)

The proof of 101 different fractions which occur in the quantum Hall effect is reported. One factor arises from the Bose-Einstein statistics for Landau levels so that the eigen values are proportional to (n+1/2). Another factor arises from the spin and the orbit. Some of the fractions arise because of a transition to zero-energy state while others arise from the transition's amongst levels. These transitions create quasiparticles in the system so that the moving quasiparticles can combine to make new two or three particle states. The energy spectrum has a variety of quasiparticles so that in a given cluster, the spin can be a fraction like 1/2, 3/2, ... or an integer like, 0, 1, 2, .... The integer spin gives rise to even denominators such as 1/2, 5/2, 7/2, 3/2, 1/6, 5/6, 3/10, 7/10, etc. There is considerable clustering of electrons in the sample. The unit of flux quantum is ?o = hc/e so that flux can quantize in units of n'?o (n' = integer). For n' = 2, the plateaus can occur at 3/8, 5/8 and 29/8. The state at 1/2 is four-fold degenerate and hence can not be described as a paired state. The factor of 8 in the denominator is a result of 1/2 from Bose-Einstein distribution, 1/2 from l and s and 1/2 from the flux quantum. But another 1/2 can arise from the cyclotron frequency. Hence there are four sources of 1/2 out of which only three are needed to obtain 1/8. Hence 3/8, 5/8 and 29/8 can not be described by a Pfaffian determinant which gives only a two particle state. However, some of the states are paired.

Shrivastava, Keshav N.

2009-07-01

227

News & Information President Chen Yiyu Meets with Omi Professor Wang Jie Meets with NSF Assistant Director Vice President Sun Jiaguang Visited Japan and Germany on International Evaluation Vice President Shen Wenqing Meets JST Delegation Vice President Wang Jie Meets with Vice President of the Royal Society of Edinburgh 12th Meeting of China-Korea Joint Committee for Basic Scientific Research Held Further Implement the Scientific Outlook for Development and Open up a New Prospect for Science Funding Panel Meeting for A3 Foresight Program 2008 held in Hangzhou Department Director's Fund for Earthquake Relief Vice President Shen Wenqing Meets IRRI Officials President Chen Yiyu Visits Taiwan Province NSFC VIP Attends the NSFC-JST Workshop 1st NSFC-JST Joint Evaluation for Funded Projects Ends Successfully NSFC Delegation Visits the U.S. Top Heads Meet at China-US Computer Science Leadership Summit President Chen Yiyu Met with Her Royal Highness Princess Maha Chari Sirindhorn of Thailand  

NASA Astrophysics Data System (ADS)

President Chen Yiyu Meets with Omi Professor Wang Jie Meets with NSF Assistant Director Vice President Sun Jiaguang Visited Japan and Germany on International Evaluation Vice President Shen Wenqing Meets JST Delegation Vice President Wang Jie Meets with Vice President of the Royal Society of Edinburgh 12th Meeting of China-Korea Joint Committee for Basic Scientific Research Held Further Implement the Scientific Outlook for Development and Open up a New Prospect for Science Funding Panel Meeting for A3 Foresight Program 2008 held in Hangzhou Department Director's Fund for Earthquake Relief Vice President Shen Wenqing Meets IRRI Officials President Chen Yiyu Visits Taiwan Province NSFC VIP Attends the NSFC-JST Workshop 1st NSFC-JST Joint Evaluation for Funded Projects Ends Successfully NSFC Delegation Visits the U.S. Top Heads Meet at China-US Computer Science Leadership Summit President Chen Yiyu Met with Her Royal Highness Princess Maha Chari Sirindhorn of Thailand

2008-01-01

228

Mid-Cycle Meeting Summary, December 8, 2010  

Center for Biologics Evaluation and Research (CBER)

Text Version... PhD, Biostatistics, DB/OBE Wei Hua, MD, PhD, MS, MHS, Epidemiology, DE/OBE Keith Peden, PhD, Product, DVP/OVRR Gang Wang, PhD, CMC ... More results from www.fda.gov/downloads/biologicsbloodvaccines/vaccines

229

The genus name Ensifer Casida 1982 takes priority over Sinorhizobium Chen et al. 1988, and Sinorhizobium morelense Wang et al. 2002 is a later synonym of Ensifer adhaerens Casida 1982. Is the combination "Sinorhizobium adhaerens" (Casida 1982) Willems et al. 2003 legitimate? Request for an Opinion.  

PubMed

The synonymy of the genera Ensifer and Sinorhizobium was recently reported, but it was proposed that the later-named genus, Sinorhizobium, take priority in nomenclature. There is no justification in the International Code of Nomenclature of Bacteria (Prokaryotes) for this step; Ensifer is the correct name of the genus, with Ensifer adhaerens as the type species. Species previously allocated to Sinorhizobium are here proposed as the new combinations Ensifer arboris, Ensifer fredii, Ensifer kostiensis, Ensifer kummerowiae, Ensifer medicae, Ensifer meliloti, Ensifer saheli, Ensifer terangae and Ensifer xinjiangensis. Sinorhizobium morelense was proposed in 2002 [Wang, E. T., Tan, Z. Y., Willems, A., Fernández-López, M., Reinhold-Hurek, B. & Martínez-Romero, E., Int J Syst Evol Microbiol 52, 1687-1693, 2002], but a consideration of all published data indicate that it is a nitrogen-fixing genomovar and later heterotypic synonym of Ensifer adhaerens. A Request for an Opinion is made as to whether or not the combination "Sinorhizobium adhaerens" (Casida 1982) Willems et al. 2003 is legitimate. PMID:14657154

Young, J M

2003-11-01

230

76 FR 72387 - Order Relating to Xun Wang  

Federal Register 2010, 2011, 2012, 2013

...items subject to the Regulations, to Pakistan, through China, for use in the Chasma...under construction in Islamabad, Pakistan, and was a subordinate entity under the ownership and control of the Pakistan Atomic Energy Commission...

2011-11-23

231

Importance of manually entering blood glucose readings when wireless-compatible meters are not being used with an insulin pump.  

PubMed

In this article by Kimberly A. Driscoll and colleagues [J Diabetes Sci Technol. 2013 Jul 1;7(4):898-903], we ommitted author Yuanyuan Tang, M.S. The full corrected author listing should read: Kimberly A. Driscoll, Ph.D.,(1) Suzanne Bennett Johnson, Ph.D.,(1) Yuxia Wang, M.P.H.,(1) Yuanyuan Tang, M.S.,(1) Elizabeth C. Gill, B.S.,(1) Adela Mitchell, R.N., B.S.N., C.D.E.,(3) Nancy Wright, M.D.,(4) and Larry C. Deeb, M.D.(1.) PMID:24124972

2013-09-01

232

A simple extension of “An alternative approach to sea surface aerodynamic roughness” by Zhiqiu Gao, Qing Wang, and Shouping Wang  

NASA Astrophysics Data System (ADS)

Based on the data previously collected during the Humidity Exchange over the Sea Main Experiment (HEXMAX), the methods used to parameterize aerodynamic roughness (z0), friction velocity (u*), and the neutral drag coefficient (CDN) under moderate wind speed conditions originally proposed by Gao et al. (2006) were extended by using the nondimensional significant wave height (gHs/u*2 or gHs/U10N2) instead of wave age (cp/u* or cp/U10N), where g is the acceleration of gravity, Hs is the significant wave height, U10Nis the horizontal wind speed at 10-m height under the neutral atmospheric condition, andcp is the phase velocity of the peak wave spectrum. The results show (1) u* = 0.024U10N(gHs/U10N2)-1/4, (2) z0 = 10 × exp[-4.797(gHs/u*2)1/6] or z0 = 10 × exp[-16.613(gHs/U10N2)1/4], and (3) CDN = 0.007(gHs/u*2)-1/3 or CDN = 5.76 × 10-4(gHs/U10N2)-1/2. The present parameterization schemes were experimentally tested.

Gao, Zhiqiu; Wang, Linlin; Bi, Xueyan; Song, Qingtao; Gao, Yuchao

2012-08-01

233

Reviews of Books  

Microsoft Academic Search

WANG ZHENPING. Ambassadors from the Islands of Immortals: China-Japan Relations in the Han-Tang Period. Honolulu: Association for Asian Studies and University of Hawaii Press, 2005. Pp. xiii, 387. $53.00 (US). Reviewed by Kent G. DengPETER WHITFIELD. Cities of the World: A History in Maps. Berkeley and Los Angeles: University of California Press, 2005. Pp. 208. $39.95 (US). Reviewed by Jeremy

Kent G. Deng; Jeremy Black; Antonio Santosuosso; Virginia Martin; Paulene Stafford; Simon MaClean; Patrick Salmon; Hugh M. Thomas; Montomery Bohna; Charles J. Halperin; David Potter; Stephen Constantine; Trevor Burnard; Kenneth Morgan; J. C. D. Clark; Dane Kennedy; Ian K. Steele; George Baer; Marshall C. Eakin; Edward Ingram; Nicholas Crafts; Ian Talbot; Ann Pottinger Saab; Lothar Hobelt; Catherine R. Schenk; Olive Patricia Dickason; Nupur Chaudhuri; John M. Mackenzie; Tony Collins; John L. Gordon Jr; Andrew J. Wilson; John Price; Warren I. Cohen; William R. Keylor; Andrew J. Crozier; Thomas G. Mahnken; John-Paul Himka; Tim Cook; Terrence Cole; S. P. Mackenzie; Akira Iriye; Carol S. Gruber; Steven I. Levine; Hector Mackenzie; Anders Stephanson; James I. Matray; Andrei Lankov; Campbell Craig; Nicholas Tarling; Marc Frey; Max Quanchi; Luis Van Isschot; Dale Torston Graden; Gary R. Hess; William M. Wardell; Eberhard Baumbauer; Bruce R. Kuniholm; Carl Cavanagh Hodge; Mark Harrison; Martin Bunton; James L. Gelvin; Lawrence S. Kaplan; J. David Singer; David A. Charters; Stephen Azzi; David A. Welch; David E. Apter; I. William Zartman; Shepard Forman; Harold James

2006-01-01

234

Uniqueness of weak solutions to the Ginzburg-Landau model for superconductivity  

NASA Astrophysics Data System (ADS)

We prove the uniqueness for weak solutions of the time-dependent 2-D Ginzburg-Landau model for superconductivity with L 2 initial data in the case of Coulomb gauge. This question was left open in Tang and Wang (Physica D, 88:139-166, 1995). We also prove the uniqueness of the 3-D radially symmetric solution in bounded annular domain with the choice of Lorentz gauge and L 2 initial data.

Fan, Jishan; Ozawa, Tohru

2012-06-01

235

Utopia and Feminism: K'ang Yu-Wei and the Ta Tung Shu  

Microsoft Academic Search

From antiquity, Chinese civilization developed technologies and advanced the modus operandi of warfare. From the middle of the nineteenth century, the Utopists, a new wave of philosophers, emerged as witnesses to the \\

KATIE E. ANDERSON

236

Pharmacological characteristics of Kampo medicine as a mixture of constituents and ingredients.  

PubMed

Herbal medicine in Japan is termed as Kampo medicine, which is derived from traditional Chinese medicine. Shakuyakukanzoto (Shao-Yao-Gan-Cao-Tang) as a kind of Kampo formulations is composed of just two components; Paeoniae Radix and Glycyrrhizae Radix, which produced marked relaxation of intestinal tract. Mokuboito (Mu-Fang-Ji-Tang) inhibited cardiac ionic channel currents, and as a mixture also produced great vasodilatation. Sinomenine (a main ingredient of Mokuboito) as a single compound also caused the vasodilatation, but decreased it along with ageing. Gypsum containing in Mokuboito and Chotosan (Diao-Teng-San) caused more marked effects, as compared with those without Gypsum. On the other hand, Rokumigan (Liu-Wei-Wan), Hachimijiogan (Ba-Wei-Di-Huang-Wan) and Goshajinkigan (Niu-Che-Shen-Qi-Wan) increase in order the number of contained ingredients. The formulations with more herbs (ingredients) produced much more effective actions on rat aorta, presumably due to compensation of the decline of pharmacological sensitivity with ageing. Thus, there are some important differences between single chemical drugs and mixture drugs with many ingredients. The effects of Kampo medicine (mixture) are never just a sum of each effect induced by a lot of ingredients. For elder persons, furthermore, Kampo medicine exerts more effective actions. PMID:23464641

Satoh, Hiroyasu

2013-01-01

237

REPLY TO COMMENT: Reply to Comment on 'Generation of cluster-type entangled coherent states'  

NASA Astrophysics Data System (ADS)

We respond to the criticism of our paper 'Generation of cluster-type entangled coherent states'. In the original paper, we remove the explicit time dependence from the interaction Hamiltonian by transforming to a rotating frame for the field operators, which is also done to quantum dots embedded in a microcavity (Djuric and Search 2007 Phys. Rev. B 75 155307). We thank Wei Haihong and Wang Faqiang for pointing out that cluster-type entangled coherent states (CTECS) cannot be obtained with the original time-dependent Hamiltonian under certain parameter condition ? Lt |?|. For the original field operators, we present a new method to generate CTECS in the same system.

Tang, Li

2010-10-01

238

Biodiversity Conservation and Pastoralism in the Tibetan Chang Tang; coexistence or conflict?  

Microsoft Academic Search

The western Tibetan plateau is currently undergoing the initiation of substantial changes in rangeland management associated with China's drive to develop the western provinces and new land tenure arrangements for pastoralists under the \\

Joseph L. Fox; Ciren Yangzong; Gesang Dunzhu; Tsechoe Dorji; Camille Richard

239

Fever of unknown origin successfully treated by oren-gedoku-to (huanglian-jie-du-tang)  

PubMed Central

Oren-gedoku-to is a traditional medicine used for treating inflammatory conditions and is given by prescription in Japan, People’s Republic of China, and Korea. Its anti-inflammatory effect is related to the arachidonate cascade and inhibition of cyclo-oxygenase, but research on other anti-inflammatory pathways is ongoing. We report a case of fever of unknown origin in a 33-year-old woman. The possibility of infection due to human immunodeficiency virus, autoimmune, neoplastic, or other disease was examined and excluded. Oren-gedoku-to was successfully used to treat her symptoms and may thus be a suitable treatment for patients with undiagnosed fever of unknown origin

Tanaka, Koichiro; Nara, Kazuhiko; Nishimura, Tetsuya; Serizawa, Keiko; Miyazaki, Taito; Urita, Yoshihisa; Miura, Oto

2013-01-01

240

History, Silence and Homelessness in Contemporary Chinese Cinema: Wang Xiaoshuai's Shanghai Dreams  

Microsoft Academic Search

Set a few years after China's opening to the various forces of globalisation, the film Shanghai Dreams (2005) tells the story of the conflict between Qinghong, a 17 year-old schoolgirl who wishes to remain in her hometown of Guiyang, and her father, Lao Wu, whose dream of returning to his hometown of Shanghai is stirred by reports of the better

Richard Letteri

2010-01-01

241

Argonne's Michael Wang talks about the GREET Model for reducing vehicle emi  

ScienceCinema

To fully evaluate energy and emission impacts of advanced vehicle technologies and new transportation fuels, the fuel cycle from wells to wheels and the vehicle cycle through material recovery and vehicle disposal need to be considered. Sponsored by the U.S. Department of Energy's Office of Energy Efficiency and Renewable Energy (EERE), Argonne has developed a full life-cycle model called GREET (Greenhouse gases, Regulated Emissions, and Energy use in Transportation). It allows researchers and analysts to evaluate various vehicle and fuel combinations on a full fuel-cycle/vehicle-cycle basis. The first version of GREET was released in 1996. Since then, Argonne has continued to update and expand the model. The most recent GREET versions are the GREET 1 2012 version for fuel-cycle analysis and GREET 2.7 version for vehicle-cycle analysis.

242

[Chemical constituents in roots of Ampelopsis sinica (Miq.) W.T. Wang].  

PubMed

Six compounds were isolated from the roots of Ampelopsis sinica and identified as lupeol, beta-sitosterol, daucosterol, catechin, sucrose and palmitic acid on the basis of spectroscopic. Lupeol is found in Ampelopsis genus for the rirst time. PMID:9388937

Chen, K

1996-05-01

243

Purification of alkaloids from Corydalis yanhusuo W. T. Wang using preparative 2-D HPLC.  

PubMed

Two-dimensional preparative multi-channel parallel high performance liquid chromatography was successfully applied for the first time to isolate and purify alkaloids from Corydalis yanhusuo. The experiments were performed in off-line mode using the same preparative chromatographic column with pH 3.5 in the first and pH 10.0 in the second separation dimension. In the preparative process, UV-triggered fraction collection was used in the first dimension while UV and MS-triggered collection were used in the second dimension for reasons of sensitivity and complementarity. Two pure compounds and nine fractions were obtained in the first dimension. Then two representative fractions were further purified in the second dimension and six pure compounds were obtained. The results demonstrated that this procedure is an effective approach for the preparative isolation and purification of alkaloids from Corydalis yanhusuo. Based on the different pH values of the mobile phase in this method, it is also suitable for the preparative isolation and purification of other compounds from TCMs which are sensitive to the pH of the solutions. Moreover, this method will be a promising tool for the purification of low content compounds from natural products. PMID:19347864

Zhang, Jing; Jin, Yu; Liu, Yanfang; Xiao, Yuansheng; Feng, Jiatao; Xue, Xingya; Zhang, Xiuli; Liang, Xinmiao

2009-05-01

244

Miyun metre-wave aperture synthesis radio telescope  

NASA Astrophysics Data System (ADS)

The Miyun metre-wave aperture synthesis radiotelescope, working at frequency of 232 MHz, consists of an E-W array of 28 elements, each of 9 m aperture. 192 baselines are effected with a full coverage of the U-V plane (Fig. 2). The longest baseline is 1,164m. This instrument is designed for source survey and detection of peculiar sources in northern declinations. A set of observations completed in 2 × 12 hours gives a thermal noise limited sensititity of 0.05 Jy and a resolution of 3'8 × 3'8 csc ?. The field of view is 8° × 8°. This should enable us to complete an overall survey of the region ? >= + 30° within two years, and to carry out monitoring of selected areas. Figures 1 and 2 show the main properties and general design of the instrument and Figures 3 and 4 give some preliminary results of sky mapping. The following persons took part in the designing and making of the telescope: WANG Hong, Wang Xin-min, Wang Shou-guan, Liu Fu-you, Pu Ting-yi, Chen Hong-shen, Qiu Yu-hai, Yang Yi-pei, Pang Lei, Zhang Chun-lu, Zhang Guo-quan, Zhang Xi-zhen, Jin Tie-lin, Zheng Yi-jia, Zhao Hui-ping, Nan Ren-dong, Kang Lian-sheng, Bao Hong-qi, Wei Ming-zhi.

1986-03-01

245

Hypolipidemic Effects of Three Purgative Decoctions  

PubMed Central

In traditional Chinese medicine (TCM), purgation is indicated when a person suffers an illness due to the accumulation of evil internal heat. Obese individuals with a large belly, red face, thick and yellow tongue fur, constipation, and avoidance of heat are thought accumulates of evil internal heat, and they are also treated with purgatives such as Ta-Cheng-Chi-Tang (TCCT), Xiao-Chen-Chi-Tang (XCCT), and Tiao-Wei-Chen-Chi-Tang (TWCCT) by TCM doctors. In previous studies, our group found that TCCT has potent anti-inflammatory activity, and that XCCT is an effective antioxidant. Since rhubarb is the principle herb in these three prescriptions, we will first present a thorough review of the literature on the demonstrated effect (or lack of effect) of rhubarb and rhubarb-containing polyherbal preparations on lipid and weight control. We will then continue our research with an investigation of the anti-obesity and lipid-lowering effect of TCCT, XCCT, TWCCT, and rhubarb extracts using two animal models. TWCCT lowered the serum triglyceride concentration as much as fenofibrate in Triton WR-1339-treated mice. Daily supplementation with XCCT and TWCCT significantly attenuated the high-fat-diet-induced hypercholesterolemia in rats. In addition, TWCCT also significantly lowered the high-fat-diet-induced hypertriglycemia. Although feeding high-fat diet rats with these extracts did not cause loose stools or diarrhea or other deleterious effects on renal or hepatic function. None of these extracts lowered the body weight of rats fed on high-fat diet. In conclusion, the results suggest that XCCT and TWCCT might exert beneficial effects in the treatment of hyperlipidemia.

Tseng, Sung-Hui; Chien, Ting-Yi; Chen, Jiun-Rong; Lin, I-Hsin; Wang, Ching-Chiung

2011-01-01

246

Landslides: Risk Analysis and Sustainable Disaster Management Edited by K. Sassa, H. Fukuoka, F.W. Wang, G. Wang. 2005 XXX, 385 p. 417 illus. 3-540-28664-0. Berlin: Springer, 2005.  

NASA Astrophysics Data System (ADS)

Based on contributions to the first General Assembly of the International Consortium on Landslides, this reference and status report emphasizes the mechanisms of different types of landslides, landslide risk analysis, and sustainable disaster management. It comprises the achievements of the ICL over the past three years, since the Kyoto assembly. It consists of three parts: research results of the International Programme on Landslides (IPL); contributions on landslide risk analysis; and articles on sustainable disaster management.

Sassa, Kyoji; Fukuoka, H.; Wang, F. W.; Wang, Gonghui

247

Soldier crab ( Dotilla myctiroides) distribution, food resources and subsequent role in organic matter fate in Ao Tang Khen, Phuket, Thailand  

NASA Astrophysics Data System (ADS)

This study aimed to elucidate Dotilla myctiroides (H. Milne-Edwards) food resources and how the soldier crab influences the organic matter composition on the intertidal flat. A preliminary assessment of D. myctiroides size, sex, and population distribution was conducted to clarify the characteristics of the inhabiting population. Overall, D. myctiroides size and abundance was normal across the tidal flat area. Comparison of different sediment types from the soldier crab habitat (surface sediments, igloos, burrow lining, burrow pellets, feeding pellets, and feces) using the fatty acid (FA) analysis technique revealed D. myctiroides removes organic matter via the significantly lower contributions of polyunsaturated FAs, essential FAs, and dinoflagellates in the feeding pellets. Dotilla myctiroides tissue analysis of the hepatopancreas and hindgut in individuals that had been starved for 24 h confirmed not only the consumption of dinoflagellates, but diatoms and macroalgae as well. In addition, the FA metabolism within the digestive system implied the ability of the soldier crab to synthesize highly unsaturated FAs (HUFAs) such as 20:4 n-6, 20:5 n-3 and 22:6 n-3.

Takagi, Kimberly K.; Cherdsukjai, Phaothep; Mimura, Izumi; Yano, Yuka; Adulyanukosol, Kanjana; Tsuchiya, Makoto

2010-05-01

248

Stratigraphy, microfacies and sedimentary environments of Asmari Formation at Tang-e-Bolhayat, north of Kazerun, Fars Province, Iran.  

NASA Astrophysics Data System (ADS)

The Oligo-Miocene Asmari Formation is the most important petroleum reservoir in the Folded Zagros Zone (FZZ). The FZZ is one of the tectono-sedimentary provinces of Iran, situated to the SW of the country and is recognized as the southwesterly boundary of the Zagros Orogen near the Persian Gulf. This area is easily recognised by the NW-SE trending parallel anticlines that verge to the SW in a 6-12 km cover sequence. As mentioned above, this area is home to some of the world largest oil reservoirs, and was the location of initial continental collision between the Arabian and Eurasian Plates. The Asmari Formation includes Kalhur (evaporates) and Ahwaz (sandstone) Members, measured in Lorestan and Khuzestan Provinces, respectively. The Asmari Formation is present throughout the Zagros Basin but it is best developed in Dezful Embayment. Most studies of the formation in this basin are related to subsurface data, while this study is focused on an outcrop. In the type section, which was measured at Kuh-e-Asmari (Asmari Mountain), SE of Masjed-e-Soleiman (a town in Khuzestan Province, SW of Iran), the formation comprises 314 m resistant, severely fractured, cream to brown limestones, with the occurrence of thin bedded shales. The lower contact with Pabdeh Formation and the upper contact with Gachsaran Formation are gradual and conformable. In the study area, from the viewpoint of lithology, the Asmari Formation consists up to 430 meters of thin to massive bedded limestone, dolomitic limestone, argillaceous limestone and occasionally marl. According to petrography and field observations and analysis of larger benthic foraminifera assemblages and microfacies features 4 major depositional environments were identified. These include open marine, barrier, lagoon and tidal flat. These environments are represented by 10 microfacies. A carbonate ramp platform is suggested for the depositional environment of the Asmari Formation. The inner ramp facies are characterized by wackstone-packstone, dominated by various taxa of imperforate foraminifera, the middle ramp facies are characterized by packstone-grainstone with diverse assemblage of larger hyaline foraminifera. The outer ramp is dominated by argillaceous wackstone and mudstone, characterized by hyaline foraminifera. On a sequence stratigraphic framework, the Lower Asmari is marly in character near the base, overlain by foraminiferal limestone, and deposited in HST stage, wears TST started during the deposition of underlying Pabded Formation and transgression reached to highest level Just in the boundary of Asmari and Pabdeh formations. The Middle Asmari is marked as late HST sediments composed of lagoonal facies (miliolidae wackstones). This sequence comprises one stage of HST, one LST and one TST. The Upper Asmari which is existed in the Dezful Embayment very well, comprises two HST and two TST; the latter began with echinoderm wackstone microfacies. Two third- order sequences are identified based on deepening and shallowing patterns in microfacies, stacking patterns and the distribution of foraminiferas. Sequence boundary is type 2 and no evidence of exposure was observed. Keywords: Stratigraphy, Microfacies, Sedimentary Environments, Kazerun, Iran.

Bahrami, M.

2009-04-01

249

Concentration and detection of SARS coronavirus in sewage from Xiao Tang Shan Hospital and the 309th Hospital  

Microsoft Academic Search

The transmission of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is associated with close contact to SARS patients and droplet secretions of those patients. The finding of positive RT-PCR results from stools of SARS patients suggests that stools of SARS patients or sewage containing stools of patients could transmit SARS-CoV. We used a novel style of electropositive filter media particle to

Xin-Wei Wang; Jin-Song Li; Ting-Kai Guo; Bei Zhen; Qing-Xin Kong; Bin Yi; Zhong Li; Nong Song; Min Jin; Wen-Jun Xiao; Xiu-Mei Zhu; Chang-Qing Gu; Jing Yin; Wei Wei; Wei Yao; Chao Liu; Jian-Feng Li; Guo-Rong Ou; Min-Nian Wang; Tong-Yu Fang; Gui-Jie Wang; Yao-Hui Qiu; Huai-Huan Wu; Fu-Huan Chao; Jun-Wen Li

2005-01-01

250

Inventing a Modern Lexicon for Grammar in Chinese: The Experience of Wang Fengzao, Ma Jianzhong and Yan Fu  

ERIC Educational Resources Information Center

|In China, from the second half of the nineteenth century to the first years of the twentieth century, extensive translation of Western works on science, economics and law was undertaken. The goal was to spread "Western learning", thought of as the key tool for the industrial and military modernization of the country, among the Chinese ruling…

Pellin, Tommaso

2008-01-01

251

Orgo Cards: Organic Chemistry Review (Steven Q. Wang, Babak Razani, Edward J. K. Lee, Jennifer Wu, and William Berkowitz)  

NASA Astrophysics Data System (ADS)

Most students are intimidated by the reputation of organic chemistry, while others see the course as nonessential to their career goals. While they usually have the ability to meet the challenge and succeed, many seek any mechanism by which they can pass the course with minimal study time. Products like Orgo Cards pander to such desires and will not be of benefit to the student with mediocre talent or poor motivation. The best students who buy this set may be bright enough to focus on those very well done mechanisms. But remember, there’s nothing in Orgo Cards that isn’t already in a good organic text.

Gooch, Eugene

2003-09-01

252

PREFACE International Symposium on Spintronic Devices and Commercialization 2010  

NASA Astrophysics Data System (ADS)

SSDC logo Preface The International Symposium on Spintronic Devices and Commercialization (ISSDC' 2010) was held in Beijing, China, from 21 to 24 October 2010. The aim of the symposium was to provide an opportunity for international experts, academics, researchers, practitioners and students working in the areas of spintronic theories, spintronic materials, and spintronic devices to exchange information on the R&D and commercialization of spintronic materials and devices. New developments, concepts, future research trends and potential commercialization areas were also discussed. The topics covered by ISSDC' 2010 were: Fundmental Spintronic Theories/Experiments Spin polarization, spin-dependent scattering, spin relaxation, spin manipulation and optimization, as well as other related characterizations and applications, etc. Spintronic Materials Giant magnetoresistance materials, magnetic tunnel junction materials, magnetic semiconductor materials, molecular spintronic materials. Spintronic Devices Sensors, isolators, spin logic devices and magnetic random access memories (MRAMs), microwave devices, spin diodes, spin transistor, spin filters and detectors, spin optoelectronic devices, spin quantum devices, single chip computer, spin molecule and single electron devices. Other Magnetic Materials Soft magnetic materials, hard magnetic materials, magneto-optical materials, magnetostriction materials. Applications of Spintronic Devices Magnetic position/angle/velocity/rotation velocity sensors, magnetic encoders, magnetic compasses, bio-medical magnetic devices and other applications. Future Research Trends and the Commercialization of Spintronic Devices Approximately 85 scientists from almost 10 countries participated in the conference. The conference featured 6 keynote lectures, 8 invited lectures, 12 contributed lectures and about 30 posters. We would like to express our gratitude to all participants for their presentations and discussions, which made the conference very successful indeed. We are also grateful to the Advisory Committee, the Conference Chairs, the Excutive Chairs, the Academic Committee, the Organization Committee and the Secretariat for their fruitful work. We would especially like to thank all the organizers listed below for their support in all aspects of the conference. We would like to express our thanks to all the authors for their time and genuine efforts, and to the reviewers for their fruitful comments during the preparation of this volume. ISSDC'2010 ORGANIZATION Advisory Committee Chialing Chien, USAJunhao Chu, ChinaBernard Dieny, FranceKoichiro Inomata, Japan Liangmo Mei, ChinaJohn Sivertsen, USAMingjing Tu, ChinaDingsheng Wang, China Zhanguo Wang, ChinaQikun Xue, ChinaWenshan Zhan, China Conference Chairs Jack Judy, USAYouwei Du, China Executive Chairs Zhenghong Qian, USAJianping Wang, USA Organization Committee ChairJiyan Luo, China Vice ChairsGuilin Duan, ChinaLingling Sun, ChinaBaogen Shen, China MembersTiecheng Lu, ChinaDa Ma, ChinaYe Tian, China Jinsong Xu, ChinaQiuling XuChangmao Yang, China Guanghua Yu, ChinaYi Yan, China Academic Committee ChairsZhenghong Qian, USAYongbing Xu, UK Vice ChairsSeongtae Bae, SingaporeYong Jiang, ChinaDexin Wang, USA Huaiwu Zhang, ChinaJianhua Zhao, China MembersJianwang Cai, ChinaXiangdong Chen, ChinaHaifeng Ding, China Chunhong Hou, USAGunther Baubock, USABin Hu, USA Jungchun Huang, TaiwanDexuan Huo, ChinaYoon H Jeong, Korea Chihuang Lai, TaiwanRunwei Li, ChinaWei Liu, China Jing Shi, USAYasushi Takemura, JapanMark Tondra, USA Shan X Wang, USADi Wu, ChinaDesheng Xue, China Minglang Yan, USAShishen Yan, ChinaXiaofei Yang, China Chun Yeol You, KoreaWei Zhao, ChinaShiming Zhou, China Jianguo Zhu, China Secretariat Secretary-generalChangmao Yang, China Vice Secretary-generalJunli Wang, ChinaJinsong Xu, ChinaYe Tian, China MembersRu Bai, ChinaHongliang Zhan, China ISSDC' 2010 Organizers Department of Science and Technology, CSIC, China SpinIC Inc., China Hangzhou Dianzi University, China State Key Laboratory of Magnetism, Institute of Physics, Chinese Academ

Du, You-wei; Judy, Jack; Qian, Zhenghong; Wang, Jianping

2011-01-01

253

Micro-turbulence driven parallel plasma current in tokamaks  

NASA Astrophysics Data System (ADS)

Global gyrokinetic simulations show that ion temperature gradient (ITG) and trapped electron mode (TEM) turbulence can drive a significant parallel current in meso-scale (zonal current). The underlying dynamics is closely related to nonlinear plasma flow generation [1] by turbulent residual stress [2]. However, unlike toroidal momentum which is mostly carried by ions, the turbulent current is mainly carried by electrons in the laboratory frame, and shows finer radial scale in comparison with poloidal and toroidal zonal flows. In both collisonless TEM and ITG turbulence, substantial electron current is first generated in the positive direction of magnetic field and remains quasi-stationary in post-saturation phase. The current generation by turbulence exhibits the similar characteristic dependence on plasma parameters as that of plasma flow generation [3]. Specifically, it increases with pressure gradient, decreases with equilibrium current Ip and increases with the radial variation of safety factor. Also discussed are interesting phase space structures between TEM and ITG turbulence driven current to elucidate the roles of resonant and non-resonant electrons. In collaboration with T. S. Hahm, P. H. Diamond (UCSD), F. L. Hinton (UCSD), A. H. Boozer (Columbia U.), G. Rewoldt, W. M. Tang and W. W. Lee. [1] W. X. Wang et al., Phys. Plasmas 17, 072511 (2010). [2] P. H. Diamond et al., Phys. Plasmas 15, 012303 (2008). [3] W. X. Wang et al., Phys. Rev. Lett. 106, 085001 (2011).

Wang, W. X.; Ethier, S.

2011-11-01

254

Novel Approaches Concerning Catalyst Deactivation. Final Report, July 1, 1982-December 31, 1983.  

National Technical Information Service (NTIS)

A complete analysis is presented of a model originally suggested by Wei and Wei (J. Wei and R.G. Wei, Metal Deposition Profiles in Hydro-Demetallation, Chem. Eng. Comm., 13, 251, 1982) to model the behavior of catalysts during hydro-demetallation of coal ...

T. T. Tsotsis

1984-01-01

255

Morphological and cytological studies of diploid and colchicine-induced tetraploid lines of crape myrtle ( Lagerstroemia indica L.)  

Microsoft Academic Search

The tips of cotyledon-stage seedlings of three crape myrtle cultivars (“Zi Wei”, “Hong Wei” and “Yin Wei”) were treated with colchicine. Various concentrations of colchicine and different treatment durations were tested. Seedlings of “Zi Wei” treated with 0.5% colchicine for 72h and seedlings of “Yin Wei” treated with colchicine (0.2% for 96h, 0.5% for 48h and 0.8% for 72h) demonstrated

Y. M. Ye; J. Tong; X. P. Shi; W. Yuan; G. R. Li

2010-01-01

256

Effect of a traditional Japanese herbal medicine, Hochu-ekki-to (Bu-Zhong-Yi-Qi Tang), on immunity in elderly persons  

Microsoft Academic Search

In general, the elderly show a significant age-related decline in their immune response, thus leading to an increased vulnerability to infections or to an increase in the occurrence of malignant tumors. In this study, we examined the effect of Hochu-ekki-to (HOT or TJ-41) on the immunological capacity of the elderly. A group of elderly patients complaining of general fatigue or

Ataru Kuroiwa; Shin'yu Liou; Hong Yan; Akihiko Eshita; Seiko Naitoh; Ariaki Nagayama

2004-01-01

257

A comprehensive platform for quality control of botanical drugs (PhytomicsQC): a case study of Huangqin Tang (HQT) and PHY906  

Microsoft Academic Search

BACKGROUND: Establishing botanical extracts as globally-accepted polychemical medicines and a new paradigm for disease treatment, requires the development of high-level quality control metrics. Based on comprehensive chemical and biological fingerprints correlated with pharmacology, we propose a general approach called PhytomicsQC to botanical quality control. METHODS: Incorporating the state-of-the-art analytical methodologies, PhytomicsQC was employed in this study and included the use

Robert Tilton; Anthony A Paiva; Jing-Qu Guan; Rajendra Marathe; Zaoli Jiang; Winfried van Eyndhoven; Jeffrey Bjoraker; Zachary Prusoff; Hailong Wang; Shwu-Huey Liu; Yung-Chi Cheng

2010-01-01

258

Vascular Pharmacology of Mokuboito (Mu-Fang-Yi-Tang) and Its Constituents on the Smooth Muscle and the Endothelium in Rat Aorta  

PubMed Central

Pharmacological actions of Mokuboito and its constituents (Sinomenium acutum and sinomenine) on rat aorta were examined. Mokuboito and S. acutum at lower concentrations (0.03–1 mg ml?1) contracted the non-loaded aorta, but at higher concentrations (1–3 mg ml?1), reversed to dilate it. The vasoconstriction was blocked by phentolamine (10 ?M). Sinomenine failed to exhibit the vasoconstriction. On the other hand, Mokuboito and S. acutum dilated the NE (5 ?M)-induced vasoconstriction: at 3 mg ml?1, by 98.9 ± 2.5% (n = 6, P < 0.01) and 97.0 ± 4.8% (n = 6, P < 0.01). Vasorelaxation induced by Mokuboito and S. acutum was attenuated by indomethacin, L-NMMA and nicardipine. Propranolol decreased the vasorelaxation induced by Mokuboito, but not by S. acutum. Sinomenine also relaxed the constriction and at 100 ?M, by 68.8 ± 5.1% (n = 7, P < 0.01). This vasorelaxation was attenuated by indomethacin, L-NMMA and nicardipine, and also by propranolol. Therefore, these results indicate that Mokuboito and its constituents exert both vasodilating actions mediated by endothelium-dependent mechanisms (PGI2 and NO from endothelium) and by endothelium-independent mechanisms (Ca2+ influx control on smooth muscle cells). Simultaneously, Mokuboito and S. acutum cause the vasoconstrictions mediated through ?-adrenoceptor stimulation, but not sinomenine. Also, Mokuboito and sinomenine possess ?-adrenoreceptor stimulating action, but not S. acutum.

Nishida, Seiichiro

2007-01-01

259

How Experts' Adaptations to Representative Task Demands Account for the Expertise Effect in Memory Recall: Comment on Vicente and Wang (1998)  

Microsoft Academic Search

K. A. Ericsson and W. Kintsch's (1995) theoretical framework of long-term working memory (LTWM) accounts for how experts acquire encoding and retrieval mechanisms to adapt to real-time demands of working memory during representative interactions with their natural environments. The transfer of the same LTWM mechanisms is shown to account for the expertise effect in unrepresentative \\

K. Anders Ericsson; Vimla Patel; Walter Kintsch

2000-01-01

260

Hubungan Sikap Kepada Wang Dan Kepuasan Kerja Terhadap Keinginan Pekerja Untuk Berhenti Secara Sukarela: Kajian Di Sebuah Organisasi Pihak Berkuasa Tempatan Berstatus Bandaraya Di Sarawak  

Microsoft Academic Search

The notion of attitude towards money as a moderating factor in job satisfaction models is less emphasised in past studies. More important, further research in this area reveals that the effect of job satisfaction characteristics (i.e. extrinsic and instrinsic factors) on voluntary turnover is not consistent when attitude towards money is considered. Therefore, this study was conducted to examine the

Azman Ismail; Mai Sumiyati Ishak; Waty Kuching

2008-01-01

261

Timing of metamorphism of the Lansang gneiss and implications for left-lateral motion along the Mae Ping (Wang Chao) strike-slip fault, Thailand  

NASA Astrophysics Data System (ADS)

The Mae Ping fault (MPF), western Thailand, exhibits dominantly left-lateral strike-slip motion and stretches for >600 km, reportedly branching off the right-lateral Sagaing fault in Myanmar and extending southeast towards Cambodia. Previous studies have suggested that the fault assisted the large-scale extrusion of Sundaland that occurred during the Late Eocene-Early Oligocene, with a geological offset of ˜120-150 km estimated from displaced high-grade gneisses and granites of the Chiang Mai-Lincang belt. Exposures of high-grade orthogneiss in the Lansang National Park, part of this belt, locally contain strong mylonitic textures and are bounded by strike-slip ductile shear zones and brittle faults. Geochronological analysis of monazite from a sample of sheared biotite-K-feldspar orthogneiss suggests two episodes of crystallization, with core regions documenting Th-Pb ages between c. 123 and c. 114 Ma and rim regions documenting a significantly younger age range between c. 45-37 Ma. These data are interpreted to represent possible magmatic protolith emplacement for the Lansang orthogneiss during the Early Cretaceous, with a later episode of metamorphism occurring during the Eocene. Textural relationships provided by in situ analysis suggest that ductile shearing along the MPF occurred during the latter stages of, or after, this metamorphic event. In addition, monazite analyzed from an undeformed garnet-two-mica granite dyke intruding metamorphic units at Bhumipol Lake outside of the Mae Ping shear zone produced a Th-Pb age of 66.2 ± 1.6 Ma. This age is interpreted to date the timing of dyke emplacement, implying that the MPF cuts through earlier formed magmatic and high-grade metamorphic rocks. These new data, when combined with regional mapping and earlier geochronological work, show that neither metamorphism, nor regional cooling, was directly related to strike-slip motion.

Palin, R. M.; Searle, M. P.; Morley, C. K.; Charusiri, P.; Horstwood, M. S. A.; Roberts, N. M. W.

2013-10-01

262

Encoding ASK Labeled CSRZ-DPSK Payload by Using Only One Dual-Drive Mach-Zehnder Modulator With Enhanced Label Performance Wei-Ren Peng, Yu-Chang Lu, Jason (Jyehong) Chen, and Sien Chi  

Microsoft Academic Search

This theoretical study presents a novel modulation scheme which simultaneously encodes the amplitude shift keying label on the carrier-suppressed return-to-zero differential phase shift keying payload using only one dual-drive Mach-Zehnder modulator. Compared with the previous scheme, in which three optical modulators are required, we offer a simple, compact, and cost-effective method. We theoretically evaluate and simulate the performance differences between

W.-R. Peng; Y.-C. Lu; S. Chi

263

Characterization of CCX140-B, an orally bioavailable antagonist of the CCR2 chemokine receptor, for the treatment of type 2 diabetes and associated complications.  

PubMed

The following manuscript was published as a Fast Forward article on February 29, 2012: Sullivan TJ, Dairaghi DJ, Krasinski A, Miao Z, Wang Y, Zhao BN, Baumgart T, Berahovich R, Ertl LS, Pennell A, Seitz L, Miao S, Ungashe S, Wei Z, Johnson D, Boring L, Tsou C-L, Charo IF, Bekker P, Schall TJ, and Jaen JC, Characterization of CCX140-B, an orally bioavailable antagonist of the CCR2 chemokine receptor, for the treatment of type 2 diabetes and associated complications. J Pharmacol Exp Ther jpet.111.190918; doi:10.1124/jpet.111.190918 It was later found that the chemical identity of a compound cited in the article, CCX140-B, was not sufficiently disclosed. The authors are unable, at this time, to provide the chemical identity of CCX140-B in accordance with the editorial policies of The Journal of Pharmacology and Experimental Therapeutics. As a result, the authors have voluntarily withdrawn this manuscript from publication. We apologize for any inconvenience this may cause JPET's readers. PMID:22378937

Sullivan, Timothy J; Dairaghi, Daniel J; Krasinski, Antoni; Miao, Zhenhua; Wang, Yu; Zhao, Bin N; Baumgart, Trageen; Berahovich, Rob; Ertl, Linda S; Pennell, Andrew; Seitz, Lisa; Miao, Shichang; Ungashe, Solomon; Wei, Zheng; Johnson, Dan; Boring, Landin; Tsou, Chia-Lin; Charo, Israel F; Bekker, Pirow; Schall, Thomas J; Jaen, Juan C

2012-06-05

264

Prediction of peptides binding to the PKA RII? subunit using a hierarchical strategy  

PubMed Central

Motivation: Favorable interaction between the regulatory subunit of the cAMP-dependent protein kinase (PKA) and a peptide in A-kinase anchoring proteins (AKAPs) is critical for translocating PKA to the subcellular sites where the enzyme phosphorylates its substrates. It is very hard to identify AKAPs peptides binding to PKA due to the high sequence diversity of AKAPs. Results: We propose a hierarchical and efficient approach, which combines molecular dynamics (MD) simulations, free energy calculations, virtual mutagenesis (VM) and bioinformatics analyses, to predict peptides binding to the PKA RII? regulatory subunit in the human proteome systematically. Our approach successfully retrieved 15 out of 18 documented RII?-binding peptides. Literature curation supported that many newly predicted peptides might be true AKAPs. Here, we present the first systematic search for AKAP peptides in the human proteome, which is useful to further experimental identification of AKAPs and functional analysis of their biological roles. Contact: tingjunhou@hotmail.com; tjhou@suda.edu.cn; wei-wang@ucsd.edu Supplementary information: Supplementary data are available at Bioinformatics online.

Hou, Tingjun; Li, Youyong; Wang, Wei

2011-01-01

265

Why Deuterium+Au was the critical control experiment at RHIC  

NASA Astrophysics Data System (ADS)

One of the striking discoveries at RHIC was the strong (factor of 4-5) suppression of high pT pions above 4 GeV/c in central Au+Au at 200 AGeV. In addition the data reveal an evolution from di-jet correlations in peripheral collisions to mono-jet production in central collisions. Two paradigms existed prior to the new D+Au data proporting to explain the same jet quenching pattern. One is based on the formation of an opaque Quark-Gluon Plasma [1]. The other is based on initial state gluon shadowing in the Color Glass Condensate model for the nuclear wavefunction [2]. I review both paradigms and how the D+Au reaction provides the critical control experiment to decide which is closer to reality under RHIC conditions. I conclude that if the preliminary d+Au data are confirmed, then a QGP was in fact formed in central Au+Au at RHIC. References: [1] M. Gyulassy, Ivan Vitev, Xin-Nian Wang, Ben-Wei Zhang nucl-th/0302077 and refs. therein. [2] Edmond Iancu, Raju Venugopalan hep-ph/0303204 and refs. therein.

Gyulassy, Miklos

2003-10-01

266

The influence of nonmonotonic synchronized flow branch in a cellular automaton traffic flow model  

NASA Astrophysics Data System (ADS)

In this paper we study the congested patterns upstream of an isolated on-ramp in a cellular automaton traffic flow model, which is proposed in our previous paper [Cheng-Jie Jin, Wei Wang, Rui Jiang, Kun Gao, J. Stat. Mech (2010) P03018]. The simulation results under open boundary conditions are presented by spatiotemporal diagrams. Our diagram of congested patterns is quite similar to that of the cellular automaton models within Kerner's three-phase traffic theory, while some differences in the "moving synchronized flow pattern" (MSP) should be noted. In our model the upstream front of MSP propagates not only upstream, but also downstream. The propagation direction depends on the flow rates and densities of free flow and synchronized flow. Besides, in our model the outflow of wide moving jams or bottlenecks could be free flow or synchronized flow, as reported in many empirical data. In the dissolving of congestions, the form of free flow may be hindered and stable synchronized flow may emerge. This phenomenon can help us understand more about the outflow. All the interesting characteristics of our model are due to the nonmonotonic structure of synchronized flow branch in the fundamental diagram, which has not been found in previous models.

Jin, Cheng-Jie; Wang, Wei

2011-11-01

267

A new apparatus for study of pressure-dependent laminar premixed flames with vacuum ultraviolet photoionization mass spectrometry.  

PubMed

We report a home-made combustion apparatus for study of pressure-dependent laminar premixed flames with tunable vacuum ultraviolet photoionization mass spectrometry. The instrument consists of a flame chamber, a photoionization chamber with a single-stage sampling system, an ion transfer/storage system, and an orthogonal-acceleration reflectron time-of-flight mass spectrometer. Preliminary results of fuel-rich C(2)H(4)/O(2)/Ar flames at pressures of 30, 150, and 760 Torr have been obtained with this instrument. Compared to previous instruments [T. A. Cool, A. McIlroy, F. Qi, P. R. Westmoreland, L. Poisson, D. S. Peterka, and M. Ahmed, Rev. Sci. Instrum. 76, 094102 (2005); F. Qi, R. Yang, B. Yang, C. Q. Huang, L. X. Wei, J. Wang, L. S. Sheng, and Y. W. Zhang, Rev. Sci. Instrum. 77, 084101 (2006)], performances of the new apparatus have higher mass resolution (~3500 at m/z = 40), better detection limit (<1 ppm), and broader dynamic range (better than 5 order of magnitude). PMID:23387669

Zhou, Z Y; Wang, Y; Tang, X F; Wu, W H; Qi, F

2013-01-01

268

Scale disparity and spectral transfer in anisotropic numerical turbulence  

NASA Astrophysics Data System (ADS)

To study the effect of cancellations within long-range interactions on local isotropy at the small scales, we calculate explicitly the degree of cancellation in distant interactions in the simulations of Yeung & Brasseur and Yeung, Brasseur & Wang using the single scale disparity parameter 's' developed by Zhou. In the simulations, initially isotropic simulated turbulence was subjected to coherent anisotropic forcing at the large scales and the smallest scales were found to become anisotropic as a consequence of direct large-small scale couplings. We find that the marginally distant interactions in the simulation do not cancel out under summation and that the development of small-scale anisotropy is indeed a direct consequence of the distant triadic group, as argued by Yeung, et. al. A reduction of anisotropy at later times occurs as a result of the isotropizing influences of more local energy-cascading triadic interactions. Nevertheless, the local-to-nonlocal triadic group persists as an isotropizing influence at later times. We find that, whereas long-range interactions, in general, contribute little to net energy transfer into or out of a high wavenumber shell k, the anisotropic transfer of component energy within the shell increases with increasing scale separations. These results are consistent with results by Zhou, and Brasseur & Wei, and suggest that the anisotropizing influences of long range interactions should persist to higher Reynolds numbers. The residual effect of the forced distant group in this low-Reynolds number simulation is found to be forward cascading, on average.

Zhou, Ye; Yeung, P. K.; Brasseur, James G.

1994-08-01

269

Deep Orogen-parallel Electrically Conductive Troughs And The Relationship To Surface Deformation In Eastern Tibet And Indochina  

NASA Astrophysics Data System (ADS)

While it is accepted that the Cenozoic collision of India and Eurasia created the world's&plargest plateau in Tibet through a range of processes including crustal thickening, delamination and extrusion, the debate continues about which tectonic processes contribute to the overall mass balance of this continent- continent collision. Competing models explaining the post-collisional deformation in Himalaya and Tibet advocate eastward extrusion of rigid blocks between slip-surfaces (Tapponier et al. 2001) or ductile crustal flow decoupling the upper and lower parts of the lithosphere (Clark and Royden, 2000; Beaumont et al., 2001). Yet, the crustal and upper mantle structure in the southeastern Himalaya-Tibet regions remains poorly understood. It is pivotal for constraining the nature of lateral extrusion or ductile flow. We recently initiated a major regional study of the eastern Himalayan syntaxis (e.g. Sun et al. 2003). Here, we present the electrical conductivity images of the lithosphere across the eastern Tibetan Plateau and off- plateau in Indochina (lat. 25-32 deg. N, long. 97-105 deg. E) which suggest the presence of a coherent and geometrically similar orogen-parallel trough-like features of low electrical resistivity in the region. We compared our images to those published by other workers (Wei et al., 2001; Unsworth et al.2004) for the regions to the west and found the troughs to be a common regional feature. We find a continuous 10-30 km thick, electrically conductive crustal layer with two pronounced ca. 150-km-wide localised downwarps that are about 30-60 km deep and can be traced from the Tibetan plateau eastwards into Indochina. The lateral terminations of these low- resistivity troughs are marked on the surface by major E-W trending (Tibet) and N-S trending (Indochina) strike- slip faults. Their axes are parallel to the dominant surface structural trend suggesting coupling between upper and lower crust. Also, zones of Cenozoic volcanism appear to be spatially related to the crustal conductive layer suggesting a link between lower crustal conductivity heterogeneity and surface deformation in and off the Tibetan plateau. We suggest that the troughs are pre-existing fold structures or buried basins and that they probably influenced crustal melt distribution and deformation in the region. Our folding interpretation is shown to be consistent with inferences from gravity and topographical data (Jin et al.,1994; Braitenberg et al. 2000). References: Beaumont, C., R. A. Jamieson, M. H. Nguyen and B. Lee, Nature, 414, 738-742, 2001. Braitenberg, C., Zado, M., Fang, J., Wang, Y. & Hsu, H.T., J. Geodynamics 30, 489-505, 2000. Clark, M. K., L. H. Royden, Geology, 28, 703-706, 2000. Jin, Y., McNutt, M. & Zhu, Y. , Nature 371, 669-674, 1994. Sun, J., G. Jin, D. Bai, and L. Wang, Science in China, 46, 243-253, 2003. Unsworth M., Wei Wenbo, Jones A., et al., JGR, 109, B02403, doi:10.1029/2002JB002305, 2004. Tapponnier P., Xu Z., Roger F., Meyer B., Arnaud N., Wittlinger G., Yang J., Science, 294 (5547), 1671-1677, 2001. Wei W., Unsworth M., Jones A., et al., Science, 292 (5517), 716-719, 2001. Yin, A., T. M. Harrison, Annual Rev. Earth Planet. Sci., 28, 211-280, 2000.

Meju, M. A.; Bai, D.; Ma, X.; Jiang, C.; Zhou, Z.; Zhao, C.; Wang, L.

2007-12-01

270

Immunomodulatory Effects of Liriope Platyphylla Water Extract on Lipopolysaccharide-Activated Mouse Macrophage  

PubMed Central

The tuber of Liriope platyphylla Wang et Tang (Liliaceae), also known as Liriopis tuber, is famous in Oriental medicine owing to its tonic, antitussive, expectorant and anti-asthmatic properties. In the present study, the effects of Liriopis tuber water extract (LP) on proinflammatory mediators secreted from lipopolysaccharide (LPS)-induced cultured RAW 264.7 mouse macrophages were investigated. Nitric oxide (NO), prostaglandin E2 (PGE2) and intracellular calcium release were measured after 24 h incubation. Various cytokines and nuclear transcription factors (NF-?B and CREB) of LPS-induced RAW 264.7 were measured by a multiplex bead array assay based on xMAP technology. LP (up to 200 ?g/mL) significantly decreased levels of nitric oxide (NO), interleukin (IL)-6, IL-10, IL-12p40, interferon-inducible protein-10, keratinocyte-derived chemokine, monocyte chemotactic protein-1, vascular endothelial growth factor, granulocyte macrophage-colony stimulating factor, platelet derived growth factor, PGE2, intracellular calcium, NF-?B and CREB in LPS-induced RAW 264.7 cells (p < 0.05). The results suggest that LP has immunomodulatory activity to reduce excessive immune reactions during the activation of macrophages by LPS. Further studies are needed to verify the precise mechanism regulating immunomodulatory activities of LP.

Kim, Hye Kyung; Lee, Ji Young; Han, Hyo-Sang; Kim, Young-Jin; Kim, Hyun Joo; Kim, Yoon-Sang; Kim, Hyung Min; Ko, Seong-Gyu; An, Hyo-Jin; Lee, Young-Jong; Park, Wansu

2012-01-01

271

The prostamide-related glaucoma therapy, bimatoprost, offers a novel approach for treating scalp alopecias  

PubMed Central

Balding causes widespread psychological distress but is poorly controlled. The commonest treatment, minoxidil, was originally an antihypertensive drug that promoted unwanted hair. We hypothesized that another serendipitous discovery, increased eyelash growth side-effects of prostamide F2?-related eyedrops for glaucoma, may be relevant for scalp alopecias. Eyelash hairs and follicles are highly specialized and remain unaffected by androgens that inhibit scalp follicles and stimulate many others. Therefore, we investigated whether non-eyelash follicles could respond to bimatoprost, a prostamide F2? analog recently licensed for eyelash hypotrichosis. Bimatoprost, at pharmacologically selective concentrations, increased hair synthesis in scalp follicle organ culture and advanced mouse pelage hair regrowth in vivo compared to vehicle alone. A prostamide receptor antagonist blocked isolated follicle growth, confirming a direct, receptor-mediated mechanism within follicles; RT-PCR analysis identified 3 relevant receptor genes in scalp follicles in vivo. Receptors were located in the key follicle regulator, the dermal papilla, by analyzing individual follicular structures and immunohistochemistry. Thus, bimatoprost stimulates human scalp follicles in culture and rodent pelage follicles in vivo, mirroring eyelash behavior, and scalp follicles contain bimatoprost-sensitive prostamide receptors in vivo. This highlights a new follicular signaling system and confirms that bimatoprost offers a novel, low-risk therapeutic approach for scalp alopecias.—Khidhir, K. G., Woodward, D. F., Farjo, N. P., Farjo, B. K., Tang, E. S., Wang, J. W., Picksley, S. M., and Randall, V. A. The prostamide-related glaucoma therapy, bimatoprost, offers a novel approach for treating scalp alopecias.

Khidhir, Karzan G.; Woodward, David F.; Farjo, Nilofer P.; Farjo, Bessam K.; Tang, Elaine S.; Wang, Jenny W.; Picksley, Steven M.; Randall, Valerie A.

2013-01-01

272

Soliton-like solutions to the generalized Burgers-Huxley equation with variable coefficients  

NASA Astrophysics Data System (ADS)

In this paper, we consider the generalized Burgers-Huxley equation with arbitrary power of nonlinearity and time-dependent coefficients. We analyze the traveling wave problem and explicitly find new soliton-like solutions for this extended equation by using the ansatz of Zhao et al. [X. Zhao, D. Tang, L. Wang, Phys. Lett. A 346 (2005) 288-291]. We also employ the solitary wave ansatz method to derive the exact bright and dark soliton solutions for the considered evolution equation. The physical parameters in the soliton solutions are obtained as function of the time-dependent model coefficients. The conditions of existence of solitons are presented. As a result, rich exact travelling wave solutions, which contain new soliton-like solutions, bell-shaped solitons and kink-shaped solitons for the generalized Burgers-Huxley equation with time-dependent coefficients, are obtained. The methods employed here can also be used to solve a large class of nonlinear evolution equations with variable coefficients.

Triki, Houria; Wazwaz, Abdul-Majid

2013-08-01

273

77 FR 67341 - Fisheries of the South Atlantic; Southeast Data, Assessment and Review (SEDAR); Public Meeting  

Federal Register 2010, 2011, 2012, 2013

...Notice of SEDAR 30 Assessment Process Webinar I for Caribbean blue tang and queen triggerfish...SUMMARY: The SEDAR 30 assessments of the Caribbean blue tang and queen triggerfish will consist of a series of workshops...

2012-11-09

274

Automatic Locking Knee Brace Joint.  

National Technical Information Service (NTIS)

This invention is an apparatus for controlling the pivotal movement of a knee brace comprising a tang-and-clevis joint that has been uniquely modified. Both the tang and the clevis have a set of teeth that, when engaged, can lock the tang and the clevis t...

B. Weddendorf

1995-01-01

275

Teacher Agency in the Performance of Inquiry-Oriented Science Curriculum Reform  

ERIC Educational Resources Information Center

In this commentary, I consider several theoretical and analytical aspects of Tang Wee Teo and Margery Osborne's case study. I begin by identifying structuralist and cultural themes in Tang Wee and Margery's theoretical model of human activity. Next, I offer an alternative interpretation for Tang Wee and Margery's reported findings in terms of the…

Oliveira, Alandeom W.

2012-01-01

276

46 CFR 160.043-4 - Construction and workmanship.  

Code of Federal Regulations, 2010 CFR

...not less than 0.095 inch thick at the tang. Shall have a triangular section and...Before assembling, the sides of the tang shall be uniformly polished. (b) Can...not less than 0.072 inch thick at the tang, and 111/16 to 115/16...

2009-10-01

277

46 CFR 160.043-4 - Construction and workmanship.  

Code of Federal Regulations, 2010 CFR

...not less than 0.095 inch thick at the tang. Shall have a triangular section and...Before assembling, the sides of the tang shall be uniformly polished. (b) Can...not less than 0.072 inch thick at the tang, and 111/16 to 115/16...

2010-10-01

278

Teacher Agency in the Performance of Inquiry-Oriented Science Curriculum Reform  

ERIC Educational Resources Information Center

|In this commentary, I consider several theoretical and analytical aspects of Tang Wee Teo and Margery Osborne's case study. I begin by identifying structuralist and cultural themes in Tang Wee and Margery's theoretical model of human activity. Next, I offer an alternative interpretation for Tang Wee and Margery's reported findings in terms of the…

Oliveira, Alandeom W.

2012-01-01

279

A review of the genus Serangium Blackburn (Coleoptera, Coccinellidae) from China  

PubMed Central

Abstract The genus Serangium Blackburn from China is reviewed. The genus Catanella Miyatake is removed from synonymy with Serangium. Serangium baculum Xiao is transferred to Catanella, as Catanella baculum (Xiao), comb. n. Twelve species of Serangium are described, keyed and illustrated, including eight new species, Serangium magnipunctatum Wang & Ren, sp. n., Serangium trimaculatum Wang & Ren, sp. n., Serangium centrale Wang & Ren, sp. n., Serangium leigongicus Wang & Ren, sp. n., Serangium latilobum Wang & Ren, sp. n., Serangium digitiforme Wang & Ren, sp. n., Serangium dulongjiang Wang, Ren & Chen, sp. n., and Serangium contortum Wang & Ren, sp. n. Serangium punctum Miyatake is newly recorded from China.

Wang, Xing-Min; Ren, Shun-Xiang; Chen, Xiao-Sheng

2011-01-01

280

DETERMINATION OF ARISTOLOCHIC ACID IN TRADITIONAL CHINESE MEDICINAL PRESCRIPTIONS, CONTAINING RADIX ARISTOLOCHIAE FANGCHI, BY HPLC  

Microsoft Academic Search

A high performance liquid chromatographic method for determination of aristolochic acid, a nephrotoxicant in traditional Chinese medicinal prescriptions containing Radix Aristolochiae Fangchi, was established. (The prescriptions included Mu-Fang-Ji-Tang, Fang-Ji-Huang-Qi-Tang, Shu-Jing-Huo-Xue-Tang, Xiao-Xu-Ming-Tang, Shang-Zhong-Xia-Tong-Yong-Tong-Feng-Fang, and Fang-Ji-Fu-Ling-Tang.) The samples were analyzed by HPLC on a LiChrospher 100 RP-18e column and detected at 395?nm with acetonitrile water and 2% (v\\/v) acetic acid (45?:?55, v\\/v)

Yuan-Shiun Chang; Jeng-Shyan Deng; Yoe-Ray Ku

2002-01-01

281

Atomic physics and quantum optics using superconducting circuits: from the Dynamical Casimir effect to Majorana fermions  

NASA Astrophysics Data System (ADS)

This talk will present an overview of some of our recent results on atomic physics and quantum optics using superconducting circuits. Particular emphasis will be given to photons interacting with qubits, interferometry, the Dynamical Casimir effect, and also studying Majorana fermions using superconducting circuits.[4pt] References available online at our web site:[0pt] J.Q. You, Z.D. Wang, W. Zhang, F. Nori, Manipulating and probing Majorana fermions using superconducting circuits, (2011). Arxiv. J.R. Johansson, G. Johansson, C.M. Wilson, F. Nori, Dynamical Casimir effect in a superconducting coplanar waveguide, Phys. Rev. Lett. 103, 147003 (2009). [0pt] J.R. Johansson, G. Johansson, C.M. Wilson, F. Nori, Dynamical Casimir effect in superconducting microwave circuits, Phys. Rev. A 82, 052509 (2010). [0pt] C.M. Wilson, G. Johansson, A. Pourkabirian, J.R. Johansson, T. Duty, F. Nori, P. Delsing, Observation of the Dynamical Casimir Effect in a superconducting circuit. Nature, in press (Nov. 2011). P.D. Nation, J.R. Johansson, M.P. Blencowe, F. Nori, Stimulating uncertainty: Amplifying the quantum vacuum with superconducting circuits, Rev. Mod. Phys., in press (2011). [0pt] J.Q. You, F. Nori, Atomic physics and quantum optics using superconducting circuits, Nature 474, 589 (2011). [0pt] S.N. Shevchenko, S. Ashhab, F. Nori, Landau-Zener-Stuckelberg interferometry, Phys. Reports 492, 1 (2010). [0pt] I. Buluta, S. Ashhab, F. Nori. Natural and artificial atoms for quantum computation, Reports on Progress in Physics 74, 104401 (2011). [0pt] I.Buluta, F. Nori, Quantum Simulators, Science 326, 108 (2009). [0pt] L.F. Wei, K. Maruyama, X.B. Wang, J.Q. You, F. Nori, Testing quantum contextuality with macroscopic superconducting circuits, Phys. Rev. B 81, 174513 (2010). [0pt] J.Q. You, X.-F. Shi, X. Hu, F. Nori, Quantum emulation of a spin system with topologically protected ground states using superconducting quantum circuit, Phys. Rev. A 81, 063823 (2010).

Nori, Franco

2012-02-01

282

Magnetic sifters and biochips for early diagnosis and therapy monitoring of cancer  

NASA Astrophysics Data System (ADS)

Magnetic nanoparticles conjugated with biomolecules or recognition moieties are finding wide applications in medicine. In this context, we are developing a micromachined magnetic sifter and magnetic nanoparticles aimed for sample preparation applications in early diagnosis of cancer. The microfabricated sifter consisting of arrays of micron sized slits etched through a silicon wafer. A magnetic film is deposited on the wafer, producing high magnetic field gradients, comparable in magnitude to gradients in planar flow devices. As the solution flows through the die, magnetic particles are captured by the magnetic material surrounding the slits. The large number of slits allows for processing of large volumes of liquid, much greater than that of planar microfluidic devices. The sifters can be simply attached to a syringe or tube, resulting in a portable and user-friendly tool for molecular biology. Separation efficiencies of ˜ 50% for one pass through the sifter have been achieved. We have also designed and fabricated several types of magnetic biochips consisting of arrays of giant magnetoresistive (GMR) spin valve detectors with appropriate dimensions, surface chemistry, and microfluidics. An advanced electronic test station has been set up as a demonstration vehicle for the integrated evaluation of our magnetic biochips with commercial and custom magnetic nanoparticle labels for DNA or protein biomarkers. The magnetic biochip is capable of detecting down to 1-30 nanotags. Real-time detection of DNA signatures and protein targets in buffer and serum samples has been successfully performed in our laboratories, suggesting that magnetic biochips hold great promises for molecular diagnostics of cancer and other diseases. In collaboration with Chris M. Earhart, Wei Hu, Robert J. Wilson, Sebastian J. Osterfeld, Robert L. White, Nader Pourmand, and Shan X. Wang @ Stanford University. This work was supported by grants from NIH (1U54CA119367-01) and DARPA/Navy (N00014-02-1-0807).

Earhart, Chris

2008-03-01

283

Magnetic field asymmetry and high temperature magnetoresistance in single-walled carbon nanotubes  

NASA Astrophysics Data System (ADS)

The length scales and scattering processes in the one-dimensional electron system in single-walled carbon nanotubes remain only partially understood. Measuring the magnetoresistance, in both linear and nonlinear response, is a way to investigate these processes. In disordered nanotubes with ballistic paths much shorter than the length, we observe magnetoresistance in the metallic regime which at low temperatures resembles the universal fluctuations and weak localization seen in higher dimensional metals. A parabolic magnetoresistance persists at room temperature, indicating a significant role for phase coherence and/or interactions at high temperatures. While the linear resistance of a two-terminal sample must be an even function of magnetic field B by Onsager's principle, the nonlinear resistance need not be. Importantly, the B-asymmetric nonlinear terms can in principle be used to infer the strength of electron-electron interactions in the sample [1]. We have therefore also measured in detail the lowest order B-asymmetric current contributions, with a focus on the B-linear term. This has apparently not been done before in any system. Consistent with general theory, at high temperatures the term is small and has a constant sign independent of Fermi energy. At low temperatures it grows and develops mesoscopic fluctuations. Although these result imply that interactions are involved in the transport, calculations specific to nanotubes are needed in order to extract interaction parameters. This work was done by the authors of Ref [2]. References: [1] E.L. Ivchenko and B. Spivak, Phys. Rev. B 66, 155404 (2002); [2] Jiang Wei, Michael Shimogawa, Zenghui Wang, Iuliana Radu, Robert Dormaier, and David H. Cobden, Phys. Rev. Lett. (Dec. 2005) (cond-mat/0506275).

Cobden, David

2006-03-01

284

DNA ligase IV from HeLa cell nuclei.  

PubMed

A human cDNA encoding a previously unrecognized DNA ligase IV has been identified (Wei, Y.-F., Robins, P., Carter, K., Caldecott, K., Pappin, D. J. C., Yu, G.-L., Wang, R.-P., Shell, B. K., Nash, R. A., Schär, P., Barnes, D. E., Haseltine, W. A., and Lindahl, T. (1995) Mol. Cell. Biol. 15, 3206-3216). Antibodies have been raised against predicted peptide sequences of DNA ligase IV and used to identify the enzyme during purification from HeLa cell nuclei. The 96-kDa DNA ligase IV and the 103-kDa DNA ligase III co-migrate during SDS-polyacrylamide gel electrophoresis and have similar column fractionation properties, which complicates the distinction between the two enzymes, but they have been separated by Mono S liquid chromatography. During initial size fractionation by gel chromatography in 1 M NaCl, DNA ligase IV elutes in the same position as the DNA ligase III-XRCC1 protein complex, indicating that DNA ligase IV is also bound to another protein or occurs as a dimer. DNA ligase IV has been purified free from other DNA ligases, and its enzymatic properties have been examined. The purified protein effectively joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. The substrate specificity of DNA ligase IV differs from those of the other two cloned human DNA ligases, I and III, with regard to their ability to join the hybrid substrates oligo(dT).poly(rA) and oligo(rA).poly(dT). DNA ligase IV occurs in part as an enzyme-adenylate complex in HeLa cell nuclear extracts. PMID:8798671

Robins, P; Lindahl, T

1996-09-27

285

Bound states for an induced electric dipole in the presence of an azimuthal magnetic field and a disclination  

SciTech Connect

Based on the Wei-Han-Wei setup [H. Wei, R. Han, and X. Wei, Phys. Rev. Lett. 75, 2071 (1995)], where a neutral particle with an induced electric dipole moment interacts with a configuration of crossed electric and magnetic fields, in this paper we study the bound states that arise when we change the Wei-Han-Wei field configuration and consider a field configuration of crossed azimuthal magnetic field and a radial electric field. Moreover, we consider here a spin-half neutral particle and the presence of a linear topological defect called disclination. We obtain the bound states in two distinct cases: in the first case, we consider that the wave function of the neutral particle is well-behaved at the origin and vanishes at the asymptotic limit; in the second case, we consider the neutral particle confined to a parabolic potential like a quantum dot.

Bakke, K. [Department of Physics, Clarendon Laboratory, University of Oxford, Oxford OX1 3PU (United Kingdom)

2010-09-15

286

Fake "Returnee" Earns 4 Million through Fraudulent Marriages: More than Ten Women Fall for His Claims of Being a Boss and Possessing a House and Car  

ERIC Educational Resources Information Center

|This article discusses the case of Wang Ruiliang. Ms. Huang filed a case against Wang Jun, alleging that he had defrauded her. Ms. Huang met a man named Wang Jun in April 2002 through a certain matrimonial agency. Before they had been together for very long, Wang Jun asked to borrow money from Ms. Huang, claiming that he was having difficulties…

Chinese Education and Society, 2005

2005-01-01

287

Morphogenetische Analyse der Färbung bei weissen Axolotln  

Microsoft Academic Search

Zusammenfassung 1.Das Hormon der Hypophyse des schwarzen Axolotls ruft eine Expansion der Melanophoren hervor und stimuliert die Pigmentbildung.2.Das Hormon der Hypophyse des wei\\\\en Axolotls besitzt dieselbe formbildende Fähigkeit — es ist imstande, die Expansion zu erhalten und die Pigmentbildung herbeizuführen.3.Die Methode der Wechseltransplantationen der Haut vom schwarzen Axolotl auf einen wei\\\\en bestätigt auch die Aktivität der Hypophyse des wei\\\\en Axolotls.4.Es

Marie A. Woronzowa

1929-01-01

288

Potent antiviral activity of topoisomerase I and II inhibitors against Kaposi's sarcoma-associated herpesvirus.  

PubMed

The lytic DNA replication of Kaposi's sarcoma-associated herpesvirus (KSHV) initiates at an origin (ori-Lyt) and requires trans-acting elements, both viral and cellular. We recently demonstrated that several host cellular proteins, including topoisomerases I and II (Topo I and II), are involved in KSHV lytic DNA replication (Y. Wang, H. Li, Q. Tang, G. G. Maul, and Y. Yuan. J. Virol. 82: 2867-2882, 2008). To assess the importance of these topoisomerases in viral lytic replication, shRNA-mediated gene silencing was used. Depletion of Topo I and II severely inhibited viral lytic DNA replication as well as virion production, suggesting essential roles of these cellular proteins in viral DNA replication. The discovery of Topo I and II as enzymes indispensable for KSHV DNA replication raises a possibility that these cellular proteins could be new targets of therapeutic approaches to halt KSHV replication and treat KSHV-associated diseases. In this report, we examined one Topo I inhibitor and several Topo II inhibitors (inclusive of Topo II poison and catalytic inhibitors) as potential therapeutic agents for blocking KSHV replication. The Topo II catalytic inhibitors in general exhibited marked inhibition on KSHV replication and minimal cytotoxicity. In particular, novobiocin, with the best selectivity index (SI = 31.62) among the inhibitors tested in this study, is effective in inhibiting KSHV DNA replication and virion production but shows little adverse effect on cell proliferation and cycle progression in its therapeutic concentration, suggesting its potential to become an effective and safe drug for the treatment of human diseases associated with KSHV infection. PMID:22106228

González-Molleda, Lorenzo; Wang, Yan; Yuan, Yan

2011-11-21

289

High Precision Spectroscopy of CH_5^+ Using Nice-Ohvms  

NASA Astrophysics Data System (ADS)

The elusive methonium ion, CH_5^+, is of great interest due to its highly fluxional nature. The only published high-resolution infrared spectrum remains completely unassigned to this date. The primary challenge in understanding the CH_5^+ spectrum is that traditional spectroscopic approaches rely on a molecule having only small (or even large) amplitude motions about a well-defined reference geometry, and this is not the case with CH_5^+. We are in the process of re-scanning Oka's spectrum, in the original Black Widow discharge cell, using the new technique of Noise Immune Cavity Enhanced Optical Heterodyne Velocity Modulation Spectroscopy (NICE-OHVMS). The high precision afforded by optical saturation in conjunction with a frequency comb allows transition line centers to be determined with sub-MHz accuracy and precision -- a substantial improvement over the 90 MHz precision of Oka's work. With a high-precision linelist in hand, we plan to search for four line combination differences to directly determine the spacings between rotational energy levels. Such a search is currently infeasible due to the large number of false positives resulting from the relatively low precision and high spectral density of Oka's spectrum. The resulting combination differences, in conjunction with state-of-the-art theoretical calculations from Tucker Carrington, may provide the first insight into the rotational structure of this unique molecular system. E. T. White, J. Tang, T. Oka, Science (1999) 284, 135--137. B. M. Siller, et al. Opt. Express (2011), 19, 24822--24827. K. N. Crabtree, et al. Chem. Phys. Lett. (2012), 551, 1--6. X. Wang, T. Carrington, J. Chem. Phys., (2008), 129, 234102.

Hodges, James N.; Perry, Adam J.; McCall, Benjamin J.

2013-06-01

290

Conduct Disorders: Are Boot Camps Effective?  

ERIC Educational Resources Information Center

|Youth diagnosed with "conduct disorder" are often placed in programs using forced compliance and coercive control. One type of intervention used to treat conduct disorder is the boot camp. The basic idea is that disruptive behaviors can be corrected by strict behavioral regulation and an emphasis on skills training (Weis & Toolis 2009; Weis

Jeter, LaVaughn V.

2010-01-01

291

HUMAN LUNG CANCER RISKS DUE TO COMPLEX ORGANIC MIXTURES OF COMBUSTION EMISSIONS  

EPA Science Inventory

The study of Xuan Wei fuel use and lung cancer mortality and also the interim case-control study suggested an association between domestic smoky coal use and Xuan Wei lung cancer. The collaborative studies of physical characterization, chemical analysis, and toxicology further su...

292

Heteroxiphia Saini & Singh (Hymenoptera, Xiphydriidae), a genus new to China with descriptions of two new species.  

PubMed

Heteroxiphia Saini & Singh, 1987 is redescribed and Heteroxiphia sinicasp. n.and Heteroxiphia tenuipalpasp. n. from China are described. A key to three species is provided and a key for separation of Heteroxiphia, Trixiphidia Wei, 1999 and Yangixiphia Wei, 2002 is also provided. PMID:21747673

Wei, Meicai; Niu, Gengyun

2011-06-02

293

Developing an Understanding of the Nature of Accessibility and Usability Problems Blind Students Face in Web-Enhanced Instruction Environments  

ERIC Educational Resources Information Center

|The central premise of this research is that blind and visually impaired (BVI) people cannot use the Internet effectively due to accessibility and usability problems. Use of the Internet is indispensable in today's education system that relies on Web-enhanced instruction (WEI). Therefore, BVI students cannot participate effectively in WEI. Extant…

Babu, Rakesh

2011-01-01

294

Heteroxiphia Saini & Singh (Hymenoptera, Xiphydriidae), a genus new to China with descriptions of two new species  

PubMed Central

Abstract Heteroxiphia Saini & Singh, 1987 is redescribed and Heteroxiphia sinica sp. n.and Heteroxiphia tenuipalpa sp. n. from China are described. A key to three species is provided and a key for separation of Heteroxiphia, Trixiphidia Wei, 1999 and Yangixiphia Wei, 2002 is also provided.

Wei, Meicai; Niu, Gengyun

2011-01-01

295

Change in Review Committee Assignment, April 2, 2012 ...  

Center for Biologics Evaluation and Research (CBER)

... Product CMC, Michael Schmitt, Product CMC, Shuang Tang, Philip Krause. Product CMC, Iryna Zubkova, Product Consult, Rabia Ballica, ... More results from www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts

296

Screaming, Cursing At Your Misbehaving Teen May Backfire  

MedlinePLUS

... Wang, an assistant professor with the department of psychology at the University of Pittsburgh School of Education. " ... Te Wang, Ph.D., assistant professor, department of psychology, University of Pittsburgh School of Education; Rahil Briggs, ...

297

Role of the Co-Chaperone, CHIP, in Androgen Independent Prostate Cancer.  

National Technical Information Service (NTIS)

Expression of Chip, a Co-Chaperone Which Interacts with the Androgen Receptor, Results in Loss of AR Expression and Growth Inhibition of Prostate Cancer Cells Waleed Hassen, Xiaoyoung Zheng, Antonio Otero, Erwin Wang, Yuancheng Wang, Sherwin Zargaroff, Ji...

W. A. Hassen

2008-01-01

298

Barrett’s esophagus  

MedlinePLUS

... ed. Philadelphia, Pa: Saunders Elsevier; 2010:chap 44. Wang, KK and Sampliner RE. Updated guidelines 2008 for ... Sharma P, Overholt BF, Wolfsen HC, Sampliner RE, Wang KK, et al. Radiofrequency ablation in Barrett's esophagus ...

299

First Committee Post Resubmission Meeting Summary ...  

Center for Biologics Evaluation and Research (CBER)

... Bhanu Kannan –on the phone. Jean Wang. Craig Znderman. ... Jean Wang will work closely with Ross Pierce to analyze the datasets. ... More results from www.fda.gov/biologicsbloodvaccines/bloodbloodproducts/approvedproducts

300

Cerebral blood volume affects blood-brain barrier integrity in an acute transient stroke model.  

PubMed

Insufficient vascular reserve after an ischemic stroke may induce biochemical cascades that subsequently deteriorate the blood-brain barrier (BBB) function. However, the direct relationship between poor cerebral blood volume (CBV) restoration and BBB disruption has not been examined in acute stroke. To quantify BBB integrity at acute stages of transient stroke, in particular for cases in which extravasation of the standard contrast agent (Gd-DTPA) is not observed, we adopted the water exchange index (WEI), a novel magnetic resonance image-derived parameter to estimate the water permeability across the BBB. The apparent diffusion coefficient (ADC) and R2 relaxation rate constant were also measured for outlining the tissue abnormality, while fractional CBV and WEI were quantified for assessing vascular alterations. The significantly decreased ADC and R2 in the ischemic cortices did not correlate with the changes in CBV or WEI. In contrast, a strong negative correlation between the ipsilesional WEI and CBV was found, in which stroke mice were clustered into two groups: (1) high WEI and low CBV and (2) normal WEI and CBV. The low CBV observed for mice with a disrupted BBB, characterized by a high WEI, indicates the importance of CBV restoration for maintaining BBB stability in acute stroke. PMID:23462571

Huang, Shuning; Kim, Jeong Kon; Atochin, Dmitriy N; Farrar, Christian T; Huang, Paul L; Suh, Ji Yeon; Kwon, Seon Joo; Shim, Woo Hyun; Cho, Hyungjoon; Cho, Gyunggoo; Kim, Young Ro

2013-03-06

301

A cross cultural comparison of pay differentials as a function of rater's sex and Money Ethic endorsement: the Matthew Effect revisited  

Microsoft Academic Search

This research extends Tang's [Tang, T. L. P. (1996). Pay differentials as a function of rater's sex, money ethic and job incumbent's sex: a test of the Matthew Effect. Journal of Economic Psychology, 17, 127–144] original study of the Matthew Effect in internal equity to an international setting and examines employees in three countries: Taiwan, the USA and the UK.

Thomas Li-Ping Tang; Adrian Furnham; Grace Mei-Tzu Wu Davis

2000-01-01

302

Teacher agency in the performance of inquiry-oriented science curriculum reform  

NASA Astrophysics Data System (ADS)

In this commentary, I consider several theoretical and analytical aspects of Tang Wee Teo and Margery Osborne's case study. I begin by identifying structuralist and cultural themes in Tang Wee and Margery's theoretical model of human activity. Next, I offer an alternative interpretation for Tang Wee and Margery's reported findings in terms of the notion of multiple teacher agencies. After that, I discuss the dramaturgical or theatrical nature of the symbolic interactionist model used by Tang Wee and Margery, focusing specifically on the issues of teacher role-taking and curriculum authorship. The paper then ends with a discussion about the significance of Tang Wee and Margery's study wherein I emphasize the need for science education researchers to give more careful consideration to teacher agency and the analytical value of theatrical metaphors from the field of social dramatism.

Oliveira, Alandeom W.

2012-09-01

303

DDIA-30: a Versatile Megabar Mutli-anvil Device for in-situ High Pressure Studies with White and Monochromatic Synchrotron Radiation  

NASA Astrophysics Data System (ADS)

We report installation and test results of the DDIA-30 apparatus, a new high pressure device jointly supported by GSECARS and COMPRES. This module is now operational in the 1000 ton press in at the insertion device beamline (13-ID-D) of the Advanced Photon Source. With the operational principle similar to that of the deformation DIA (D-DIA) [1], the DDIA-30 is much larger in size, with anvil truncation edge lengths (TEL) in excess of 30 mm and hydraulic load capacity of 1000 tons. The upper and lower guide blocks have built-in differential hydraulic rams, so that the upper and lower anvils can be driven independently, generating a controlled differential stress field. When operated in single-stage mode, the device allows large samples (up to ~10 mm) to be deformed under high pressure and temperature, in a way identical to the small D-DIA that has been in operation since 2004 at 13-BM-D. The large TEL and load capacity makes DDIA-30 more attractive in double-stage configurations. Without driving the differential rams, DDIA-30 is used to compress eight second-stage cubic anvils. This 6-8 (6 first-stage and 8 second-stage anvils) configuration has been demonstrated to reach 90+ GPa with sintered diamond as second-stage anvils [2, 3]. We have tested this configuration with both LaCrO3 and TiB2 as heater materials to 35 GPa and 1500 C and successfully conducted melting experiments on selected metals and alloys with energy-dispersive diffraction and imaging. Another type of second-stage configuration is to use six DIA anvil extensions with small TELs. This 6-6 configuration [4] allows deformation experiments to be conducted without having to change the large first-stage anvils when different sized cell assemblies are desired. Recent laboratory studies using a similar device in Japan have shown that the large guide blocks have unique advantages in maintaining anvil alignment, greatly expanding capability of the deformation DIA to 25 GPa and 2000 K [5]. Monochromatic diffraction is the preferred detection technique for this configuration. The new DDIA-30 adds a powerful tool for the large-volume high pressure community. References [1] Wang, Y., et al. (2003) Rev. Sci. Instrum., 74, 3002. [2] Tange, Y., et al. (2008) High Pressure Research, 28, 245. [3] Ito, E., et al. (2010) Earth and Planetary Science Letters, 293, 84. [4] Nishiyama, N., et al. (2008) High Pressure Research, 28, 307. [5] Kawazoe, T., et al. (2010) High Pressure Research, 30, 167.

Wang, Y.; Jing, Z.; Hilairet, N.; Yu, T.; Nishiyama, N.; Tange, Y.; Sakamaki, T.; Rivers, M. L.; Sutton, S. R.

2010-12-01

304

Central bank intervention and exchange rate volatility 1 I am grateful to seminar participants at Cornell, Georgetown, Harvard, Maastricht, McGill, NBER, MIT, NYU, Penn, and especially Susan Collins, Sylvester C.W. Eijffinger, Michael Klein, Jim Stock, and Shang-Jin Wei for helpful comments and suggestions on previous drafts. This research has been supported by NSF grant SBR9311507 and the Olin Fellowship program at the NBER. 1  

Microsoft Academic Search

This paper explores the effects of foreign exchange intervention by central banks on the behavior of exchange rates. The G-3 central banks have undertaken an unprecedented number of both coordinated and unilateral intervention operations in the last 10 years. Existing empirical evidence on the effectiveness of intervention is mixed: studies using data from the 1970s suggest that intervention operations that

Kathryn M. Dominguez

1998-01-01

305

Stable Isotope Fractionation during Cr(III) oxidation by manganese oxides Swati Joshi (sjoshi@calstatela.edu), Wang D T (dtw@mit.edu), Ellis A S (aellis3@calstatela.edu) Johnson T M (tmjohnsn@uius.edu), Bullen T D (tdbullen@usgs.gov)  

NASA Astrophysics Data System (ADS)

Cr stable isotope ratios are being used to monitor Cr redox reactions and associated environmental applications. Previous studies have shown that isotope fractionation (expressed as ?53Cr in the remaining reactant Cr(VI) pool) during Cr(VI) reduction ranges from -1.8% to -4.2 % depending on the reducing agent and processes. A few studies have also been put forth for Cr isotope fractionation during oxidation reactions but mechanisms of isotope fractionation during the oxidation process are not well understood. Oxidation of Cr(III) by pyrolusite (?-MnO2) results in Cr(VI) enriched in 53Cr by +1.1%. We present here a summary of the Cr isotope fractionation during the Cr(III) to Cr(VI) oxidation process using different manganese oxides with recent data from oxidation caused by birnessite and manganite. Both birnessite (?-MnO2) and manganite (MnOOH) are considered common secondary forms of manganese oxides. Manganite is often associated with pyrolusite and some studies have also noted the reductive transformation of birnessite to manganite. Experiments with birnessite and manganite are conducted under varying pH (4 to 6), temperature (4oC and 22oC) and concentration of Cr(III) (10 to 50 mg/L) and Mn-oxides (100 to 500 mg/L). During Cr(III) oxidation with birnessite, we observed ?53Cr of the Cr(VI) product ranging from -0.5% to -0.07%. These results differ markedly from those obtained from oxidation with pyrolusite. Here, during oxidation with birnessite, the final Cr(VI) product is depleted in the heavier isotopes, while oxidation with pyrolusite produces Cr(VI) enriched in the heavier isotopes. We attribute these differences to different rates and isotope fractionations associated with the multi-step electron exchange mechanism and to structural differences between the manganese oxides. Cr(III) oxidation on manganite is generally similar to both pyrolusite and birnessite but the different structure and mixed oxidation state of Mn may result in isotope fractionations that are different from the previous form of Mn-oxides examined. The variations in Cr isotope fractionations seen with the different oxidation mechanisms are critical in interpreting Cr stable isotopes where oxidation reactions mobilize Cr.

Joshi, S.; Wang, D.; Ellis, A. S.; Johnson, T. M.; Bullen, T. D.

2011-12-01

306

Combining the Biot-Geertsma-Gassmann equation with the Batzle-Wang formulation to produce a modeling solution for predicting (a)dry rock bulk modulus, rigidity modulus, and (b)seismic velocities and reflection coefficients in porous fluid-filled rocks, with applications to laboratory rock  

Microsoft Academic Search

Two of the needed input parameters for predicting velocities in porous, fluid-filled rocks, the bulk modulus of the empty, porous rock and the shear modulus of the rock, are very difficult to obtain in situ. In the past, these values were typically chosen a priori and input into the BGG and shear-wave equations in a forward modeling mode. It is

Alvin Benson

1998-01-01

307

Mid-Holocene variability of the East Asian monsoon based on bulk organic ?13C and C/N records from the Pearl River estuary, southern China  

NASA Astrophysics Data System (ADS)

Understanding the mid-Holocene dynamics of the East Asian monsoon (EAM) is integral to modelling the Holocene development of the global climate system (Webster et al., 1998). Thus the mid-Holocene EAM history was reconstructed using bulk organic carbon isotopes (?13C), total carbon to total nitrogen (C/N) ratios and total organic carbon (TOC) from a sediment core (UV1), at a mean resolution of 10 years, from the Pearl River estuary, southern China. Sedimentary ?13C, C/N and TOC from the Pearl River estuary is a good indicator of changes in monsoonal precipitation strength (Zong et al., 2006; Yang et al., 2010), eg sediments buried during a period of high precipitation exhibit a high proportion of terrigenous sediments, and have low ?13C and high C/N, and vice versa (Yu et al., 2010). Results suggest a general decreasing trend in monsoonal precipitation from 6650-2215 cal yr BP due to the weakening insolation over northern hemisphere most likely related to the current precession circle (An, 2000). Superimposed on this trend are apparent dry-wet oscillations at centennial to millennial timescales most likely in response to solar activity. Mismatch between ?13C and results from the Dongge Cave in southern China at millennial-timescale oscillations (Wang et al., 2005), may indicate that the ?13C from the Pearl River estuary reveals changes in precipitation in a broader area than the ?18O from Dongge Cave does. Reference An Z (2000) The history and variability of the East Asian paleomonsoon climate. Quaternary Science Reviews 19: 171-187. Wang Y, Cheng H, Edwards RL, He Y, Kong X, An Z, Wu J, Kelly MJ, Dykoski CA and Li X (2005) The Holocene Asian Monsoon: Links to Solar Changes and North Atlantic Climate. Science 308: 854-857. Webster PJ, Magaña VO, Palmer TN, Shukla J and Tomas RA (1998) Monsoons: Processes, predictability, and the prospects for prediction. Journal of Geophysical Research 103(C7): 14451-14510. Yang S, Tang M, Yim WWS, Zong Y, Huang G, Switzer AD and Saito Y Burial of organic carbon in Holocene sediments of the Zhujiang (Pearl River) and Changjiang (Yangtze River) estuaries. Marine Chemistry In Press, Corrected Proof. Yu F, Zong Y, Lloyd JM, Huang G, Leng MJ, Kendrick C, Lamb AL and Yim WWS (2010) Bulk organic ?13C and C/N as indicators for sediment sources in the Pearl River delta and estuary, southern China. Estuarine, Coastal and Shelf Science 87(4): 618-630. Zong Y, Lloyd JM, Leng MJ, Yim WW-S and Huang G (2006) Reconstruction of Holocene monsoon history from the Pearl River Estuary, southern China, using diatoms and carbon isotope ratios. The Holocene 16(2): 251-263.

Yu, F.; Lloyd, J. M.; Zong, Y.; Leng, M. J.; Switzer, A. D.; Yim, W. W.; Huang, G.

2010-12-01

308

Model estimate of mercury emission from natural sources in East Asia  

NASA Astrophysics Data System (ADS)

East Asia is one of the largest source regions that release mercury into the atmosphere. Although extensive studies have been devoted to estimating the anthropogenic mercury emission, little is known about mercury emission from natural sources in the region. In this study, we adapt the algorithms developed previously, coupled with detailed GIS data and satellite LAI products, to estimate mercury emission from natural sources including vegetation, soil, and water surfaces in an East Asian domain containing 164 × 97 grid cells at a spatial resolution of 36 km. Seasonal simulations were performed to project the annual emission quantity. The simulated emission shows strong diurnal and seasonal variations due to meteorology and vegetation coverage. The annual emission in the form of gaseous elemental mercury (GEM) from the domain in 2001 is estimated to be 834 Mg, with 462 Mg contributed from China. The estimated GEM emission is comparable to the reported anthropogenic emission of 575 ± 261 Mg (56% GEM, 32% reactive gaseous mercury, 12% particulate mercury; Wu, Y., Wang, S., Streets, D.G., Hao, J., Chan, M., Jiang, J., 2006. Trends in anthropogenic mercury emissions in China from 1995 to 2003. Environmental Science & Technology 40, 5312-5318) in China for the year 2001, and dominates the anthropogenic emission during the warm season. Combining the anthropogenic and natural emission estimates, the total mercury emission from China is 776-1298 Mg, with GEM being in the range of 660-1000 Mg. The latter is similar to the GEM emission quantity inferred from aircraft measurement (765 Mg; Friedli, H.R., Radke, L.F., Prescott, R., Li, P., Woo, J.-H., Carmichael, G.R., 2004. Mercury in the atmosphere around Japan, Korea and China as observed during the 2001 ACE Asia field campaign: measurements, distributions, sources, and implications. Journal of Geophysical Research 109, D19 S25) and modeling estimate (1140 Mg; Pan, L., Chai, T., Carmichael, G.R., Tang, Y., Streets, G.G., Woo, J.-H., Friedli, H.R., Radke, L.F., 2007a. Top-down estimate of mercury emissions in China using four-dimensional variational data assimilation. Atmospheric Environment 41, 2804-2819) in China for the year 2001. The estimated natural emission helps explain the gap between the anthropogenic emission estimates based on activity data (e.g., Pacyna, J.M., Pacyna, E., Steenhuisen, F., Wilson, S., 2006. Global anthropogenic mercury emission inventory for 2000. Atmospheric Environment 40, 4048-4063; Wu, Y., Wang, S., Streets, D.G., Hao, J., Chan, M., Jiang, J., 2006. Trends in anthropogenic mercury emissions in China from 1995 to 2003. Environmental Science & Technology 40, 5312-5318) and the emission inferred from field observations (e.g., Jaffe, D., Prestbo, E., Swartzendruber, P., Weiss-Penzias, P., Kato, S., Takami, A., Hatakeyama, S., Kajii, Y., 2005. Export of atmospheric mercury from Asia. Atmospheric Environment 39, 3029-3038; Weiss-Penzias, P., Jaffe, D., Swartzendruber, P., Hafner, W., Chand, D., Prestbo, E., 2007. Quantifying Asian and biomass burning sources of mercury using the Hg/CO ratio in pollution plumes observed at the Mount Bachelor observatory. Atmospheric Environment 41, 4366-4379) in the region.

Shetty, Suraj K.; Lin, Che-Jen; Streets, David G.; Jang, Carey

309

Graphical analysis of barrel-tamped explosively accelerated flyer plates.  

National Technical Information Service (NTIS)

Analytical equations for barrel-tamped explosively accelerated flyer plates are used to generate graphical solutions to flyer problems. Given the problem geometrical dimensions, explosive weight, detonation velocity, explosive exponent, barrel-tamping wei...

M. G. Vigil

1990-01-01

310

A new species of Pseudaulacaspis MacGillivray, 1921 from China (Hemiptera, Coccoidea, Diaspididae) with a key to Chinese species  

PubMed Central

Abstract A new species of armored scale, Pseudaulacaspis zhenyuanensis Wei & Feng, sp. n. is described and illustrated from specimens collected on Spermadictyon suaveolens in China. A key to armored scale species known from China is provided.

Wei, Jiu-Feng; Feng, Ji-Nian

2012-01-01

311

Charged hard spheres in a uniform neutralizing background: The role of thermodynamics selfconsistence.  

National Technical Information Service (NTIS)

Calculations of the thermodynamic properties and pair distribution function of a one-component classical fluid of charged hard spheres in a uniform neutralizing background are reported and compared with Monte Carlo results of Hansen and Weis. Thermodynami...

Z. Badirkhan G. Pastore M. P. Tosi

1991-01-01

312

Color mixing and image enhancement  

NSDL National Science Digital Library

Wei Luo, Northern Illinois University Summary The objectives of this lab are: (1) to be familiar with reflectance spectra of vegetation especially in infrared region and understand color mixing; (2) to experience ...

Luo, Wei

313

An Efficient Technique for Determining Apparent Temperature Distributions from Antenna Temperature Measurements.  

National Technical Information Service (NTIS)

A method by which the apparent microwave temperature characteristic of a flat scene is estinated from dual polarized measurements is derived and interpreted. Approximate linear relationships between antenna and apparent temperatures are established by wei...

A. K. Fung J. P. Claassen

1973-01-01

314

1D Nanostructures: Controlled Fabrication and Energy Applications  

SciTech Connect

Jian Wei, Xuchun Song, Chunli Yang, and Michael Z. Hu, 1D Nanostructures: Controlled Fabrication and Energy Applications, Journal of Nanomaterials, published special issue (http://www.hindawi.com/journals/jnm/si/197254/) (2013).

Hu, Michael Z. [ORNL

2013-01-01

315

78 FR 42107 - Certain Wireless Devices With 3G Capabilities and Components Thereof; Notice of Request for...  

Federal Register 2010, 2011, 2012, 2013

...337-TA-800] Certain Wireless Devices With 3G Capabilities...order against certain wireless devices with 3G capabilities...by respondents Huawei Technologies Co., Ltd. of Shenzhen, China; FutureWei Technologies, Inc. d/b/a...

2013-07-15

316

apartment information system  

NSDL National Science Digital Library

Wei Luo, Northern Illinois University Summary The purpose of this project is to familiarize the student with the entire process of creating a GIS project from data capture through analysis and generating the final ...

Luo, Wei

317

Force reconstruction using the sum of weighted accelerations technique -- Max-Flat procedure.  

National Technical Information Service (NTIS)

Force reconstruction is a procedure in which the externally applied force is inferred from measured structural response rather than directly measured. In a recently developed technique, the response acceleration time-histories are multiplied by scalar wei...

T. G. Carne R. L. Mayes V. I. Bateman

1993-01-01

318

FDA Advisory Committee Background Document to the ...  

Center for Biologics Evaluation and Research (CBER)

Text Version... Open Public Hearing Speakers: Peter Jackson; Roderic G. Eckenhoff, MD; Art Van Zee, MD; Huafeng Wei, MD, Ph.D.; Lewis Coleman; Scott Kelley ... More results from www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials

319

NCI Funded Research Portfolio - ZIA CP010121-10349 Detail  

Cancer.gov

Females in Xuan Wei County are almost all non-smokers, yet they have the highest lung cancer rate in China. Non-smoking women in Xuan Wei who use smoky coal in their home can inhale ten-times higher levels of PAHs than a 20 cigarette per day active smoker, and air concentrations approach levels experienced by workers on the top-side of coke ovens.

320

Comment on ``Three-dimensional numerical investigation of electron transport with rotating spoke in a cylindrical anode layer Hall plasma accelerator'' [Phys. Plasmas 19, 073519 (2012)  

NASA Astrophysics Data System (ADS)

The oscillation behavior described by Tang et al. [Phys. Plasmas 19, 073519 (2012)] differs too greatly from previous experimental and numerical studies to claim observation of the same phenomenon. Most significantly, the rotation velocity by Tang et al. [Phys. Plasmas 19, 073519 (2012)] is three orders of magnitude larger than that of typical ``rotating spoke'' phenomena. Several physical and numerical considerations are presented to more accurately understand the numerical results of Tang et al. [Phys. Plasmas 19, 073519 (2012)] in light of previous studies.

Ellison, C. L.; Matyash, K.; Parker, J. B.; Raitses, Y.; Fisch, N. J.

2013-01-01

321

Proceedings: A Meeting on the Evaluation of External Effects of Water Projects Held at Washington, DC on 21 September 1981.  

National Technical Information Service (NTIS)

Brief Summaries of Papers Presented: Evaluation of External of Water Resources Projects - James Tang; External Effects and NED Evaluation - Frank H. Bollman; Decisions, Externalities, and the With and Without Conditions - Brad Fowler; External Effects and...

J. Tang F. H. Bollman B. Fowler R. H. Leonard S. B. Zvi

1983-01-01

322

Zoster Studies Memorandum - MenHibrix  

Center for Biologics Evaluation and Research (CBER)

... Through: Philip Krause, MD, Robin Levis, Ph.D. From: Shuang Tang, Ph.D. CC ... aspects of the assay validation appear to be less than optimal, if the ... More results from www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts

323

Rhodium catalyzed enantioselective cyclization of substituted imidazoles via C-H bond activation.  

PubMed

The enantioselective intramolecular alkylation of substituted imidazoles with enantiomeric excesses up to 98% has been accomplished by rhodium catalyzed C-H bond functionalization with (S,S',R,R')TangPhos as the chiral ligand. PMID:19662249

Tsai, Andy S; Wilson, Rebecca M; Harada, Hitoshi; Bergman, Robert G; Ellman, Jonathan A

2009-06-02

324

Improving Vaccine Manufacturing Evaluation for Bacterial ...  

Center for Biologics Evaluation and Research (CBER)

... Menzies SL, Kadwad V, Pawloski L, Lin TL, Baughman AL, Martin M, Tondella ML ... SJ, Tang WJ, Clement KH, Eaton LJ, Kelly-Cirino CD, McKee ML ... More results from www.fda.gov/biologicsbloodvaccines/scienceresearch/biologicsresearchareas

325

UNITED STATES OF AMERICA DEPARTMENT OF HEALTH ...  

Center for Biologics Evaluation and Research (CBER)

Text Version... operate the slide, though. It's not working. Oh. Sorry. ... I would recommend that during the break you personally work with Dr. Tang. DR. ... More results from www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials

326

US Food and Drug Administration Notice: Archived Document  

Center for Biologics Evaluation and Research (CBER)

Text Version... Clinical: Martin Cohen, Clinical TL: John Johnson Chemistry: Jean Tang Chemistry TL: Liang Zhou Pharm/Tox: Kimberly Benson ... More results from www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials

327

Self-Organized Criticality and the Barkhausen Effect.  

National Technical Information Service (NTIS)

The Barkhausen effect was studied in an amorphous alloy. The data exhibit all the attributes of self-ordered critical behavior enumerated by Bak, Tang, and Wiesenfeld: The distribution of lifetimes and areas of discrete Barkhausen pulses follow powerlaw d...

P. J. Cote L. V. Meisel

1992-01-01

328

77 FR 21787 - Center for Scientific Review; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892, (Telephone Conference Call). Contact Person: Careen K Tang-Toth, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge...

2012-04-11

329

76 FR 55077 - Center for Scientific Review; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892, (Telephone Conference Call). Contact Person: Careen K Tang-Toth, PhD, Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive,...

2011-09-06

330

77 FR 48527 - Center for Scientific Review; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892, (Telephone Conference Call). Contact Person: Careen K Tang-Toth, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge...

2012-08-14

331

77 FR 5260 - Center for Scientific Review; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...Embassy Suites at the Chevy Chase Pavilion, 4300 Military Road NW., Washington, DC 20015. Contact Person: Careen K Tang-Toth, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge...

2012-02-02

332

77 FR 61770 - Center for Scientific Review; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...Embassy Suites at the Chevy Chase Pavilion, 4300 Military Road NW., Washington, DC 20015. Contact Person: Careen K Tang-Toth, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge...

2012-10-11

333

78 FR 25280 - Center for Scientific Review; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892, (Telephone Conference Call). Contact Person: Careen K Tang-Toth, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge...

2013-04-30

334

Kinematic and Clinical Analyses of Upper-Extremity Movements After Constraint-Induced Movement Therapy in Patients With Stroke: A Randomized Controlled Trial  

Microsoft Academic Search

Wu CY, Chen CL, Tang SF, Lin KC, Huang YY. Kinematic and clinical analyses of upper-extremity movements after constraint-induced movement therapy in patients with stroke: a randomized controlled trial.

Ching-yi Wu; Chia-ling Chen; Simon F. Tang; Keh-chung Lin; Ya-ying Huang

2007-01-01

335

77 FR 64813 - National Cancer Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...grant applications. Place: Hilton Washington/Rockville, 1750 Rockville Pike, Rockville, MD 20852. Contact Person: Delia Tang, MD, Scientific Review Officer, Research Programs Review Branch, Division of Extramural Activities, National Cancer...

2012-10-23

336

75 FR 34456 - Center for Scientific Review; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892, (Telephone Conference Call). Contact Person: Delia Tang, MD, Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive,...

2010-06-17

337

Experimental Research on Artemisia Decoction and General Attack Therapy in Cholelithiasis.  

National Technical Information Service (NTIS)

This article deals with the determination of the normal values and ranges of bile flow, bile content and Oddi's sphincter tension in 33 anesthetized dogs and Yinchen dandao tang (artemisia decoction or AD) action on these biliary tract parameters. Mainly ...

Y. Zhongfu G. Zhaogui

1980-01-01

338

FAMA for Zoster Studies Memo - MenHibrix  

Center for Biologics Evaluation and Research (CBER)

... Ph.D. Robin Levis, Ph.D. From: Shuang Tang, Ph.D. CC: Joseph ... GlaxoSmithKline (GSK) Biologicals requests approval of a candidate vaccine “ ... More results from www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts

339

List of Firms Receiving Warning Letters for Marketing ...  

Center for Food Safety and Applied Nutrition (CFSAN)

... H & L World Wide Inc. South El Monte, California, PureGels GlucoTrim 24; Diamaxol Blood Sugar Support; Jiang Tang Pian (Diabetes Care). ... More results from www.fda.gov/food/complianceenforcement/warningletters

340

Feedback Control of Marangoni-BÉnard Convection  

NASA Astrophysics Data System (ADS)

It is demonstrated theoretically that control strategies, similar to the ones previously developed by Tang & Bau (Tang, J., & Bau, H. H., 1994, Proceedings Royal Society A, 447, 587-607.) (Tang, J., & Bau, H. H., 1998, J. Fluid Mechanics, 363, 153-171.) (Tang, J., & Bau, H. H., 1998, Physics of Fluids, 10, 1597-1610.) for postponing the transition from the conduction to the motion state in Rayleigh-Bénard convection, can also be used to delay the transition from the no-motion state to convection in the Marangoni-Bénard problem of an infinite fluid layer with a deformable surface and heating from below. For relatively small and moderate controller gains, the critical Marangoni number for the onset of convection increases monotonically as the controller gain increases and the principle of exchange of stability is preserved. Large controller gains induce oscillatory convection.

Bau, Haim

1998-11-01

341

78 FR 21365 - Ocean Transportation Intermediary License Applicants  

Federal Register 2010, 2011, 2012, 2013

...President (QI), Patricia Kolmel, Secretary, Application Type: New OFF License. Seahorse Forwarding Ltd (NVO & OFF), One Euclid Road, Fort Lee, NJ 07024, Officers: Mary C. Sullivan, Vice President (QI), Chi W. Tang, President, Application...

2013-04-10

342

Reply to Comment by R. M. W. Musson  

NASA Astrophysics Data System (ADS)

Musson's comment on our article is a good example of ``the inability of PSHA proponents to communicate clearly and directly to anyone but themselves just what it is that they are doing'' [Hanks and Cornell, 1994, p. I/1-1]. Musson's [2004] comment on an earlier paper by Wang et al. [2003] was addressed in a response by Wang et al. [2004]. However, it seems that Musson is still sure he is right and Wang et al. are all wrong when he says, ``I pointed out [Musson, 2004] the fallacies in a paper by Wang et al. [2003]. These errors are now repeated by Wang and Ormsbee [2005], who refer back to Wang et al. [2003] but not to Musson [2004]''. Now Musson is trying to impose his self-righteousness on the whole scientific community by asking Eos not to publish any paper that contains a point of view different from his.

Wang, Zhenming

2005-09-01

343

Laser surface alloying of a marine propeller bronze using aluminium powder  

Microsoft Academic Search

In a previous study laser surface melting (LSM) was employed to improve the cavitation erosion resistance of manganese–nickel–aluminium–bronze (MAB)[9,10][C.H. Tang, F.T. Cheng, H.C. Man, Surf. Coat. Technol. 182 (2004) 300; C.H. Tang, F.T. Cheng, H.C. Man, Mater. Sci. Eng. A 373 (2004) 195]. To further enhance the improvement, laser surface alloying (LSA) using fine aluminum powder has been attempted in

C. H. Tang; F. T. Cheng; H. C. Man

2006-01-01

344

And the Wagon Came Rolling In . . . : Legend and the Politics of (Self) Censorship in Nineteenth-Century Denmark  

Microsoft Academic Search

Buried in the thousands of pages of Evald Tang Kristensen’s remarkable collection of nineteenth century Danish folklore is an amusing, yet shockingly obscene, story told by “Bitte” Jens Kristensen, a cobbler and smallholder from northern Jutland. Tang Kristensen’s decision to break the story into three parts, publishing two of those parts separately, and not publishing the most obscene section of

Timothy R. Tangherlini

2008-01-01

345

Therapeutic effects of herbal medicines (Juzen-taiho-to and Ryutan-shakan-to) in a rat intrauterine infection (pyometra) model  

Microsoft Academic Search

The herbal medicines Juzen-taiho-to (Shi-quan-da-bu-tang) and Ryutan-shakan-to (Long-dan-xie-gan-tang) have both been used concurrently for the treatment of infectious diseases. We assessed their bacteriologic efficacy in a rat microbial infection (pyometra) model. Aqueous extracts of the herbal medicines were tested in vitro for minimum inhibitory concentration against Escherichia coli and Bacteroides fragilis strains, whereas an aqueous suspension was given orally for

Hiroshige Mikamo; Kyoko Kawazoe; Koji Izumi; Yasumasa Sato; Teruhiko Tamaya

1997-01-01

346

Effects of crude herbal ingredients on intrauterine infection in a rat model  

Microsoft Academic Search

We investigated the effects of crude ingredients that compose Juzen-taiho-to (Shi-quan-da-bu-tang) and Ryutan-shakan-to (Long-dan-xie-gan-tang) using in vitro and in vivo experimental models. Juzen-taiho-to consists of 10 crude ingredients extracted from herbs: Astragali Radix, Glycyrrhizae Radix, Cinnamomi Cortex, Rehmanniae Radix, Paeoniae Radix, Cnidii Rhizoma, Atractylodis Lanceae Rhizoma, Angelicae Radix, Ginseng Radix, and Hoelen. Ryutan-shakan-to consists of 9 crude ingredients extracted from

Hiroshige Mikamo; Kyoko Kawazoe; Koji Izumi; Yasumasa Sato; Teruhiko Tamaya

1998-01-01

347

The physical foundation, developmental history, and ultra-wideband performance of SMM (spiral-mode microstrip) antennas  

Microsoft Academic Search

The paper reviews the physical foundation, developmental history, and ultra-wideband (UWB) performance of the SMM (spiral-mode microstrip) antenna (Wang, J.J.H. and Tripp, V.K., 1996; Wang, 1997; Wang et al., 2005). The paper is inspired by the recent article on self-complementary (SC) antennas by Y.Mushiake (see IEEE Antennas and Propag. Magazine, vol.46, 2004; IEEE Antennas and Propag. Symp. Dig., 2003), and

Johnson J. H. Wang

2005-01-01

348

Transducers with Programmable Input by DNA Self-assembly  

Microsoft Academic Search

\\u000a Notions of Wang tiles, finite state machines and recursive functions are tied together. We show that there is a natural way\\u000a to simulate finite state machines with output (transducers) with Wang tiles and we show that recursive (computable) functions\\u000a can be obtained as composition of transducers through employing Wang tiles. We also show how a programmable transducer can\\u000a be self-assembled

Natasa Jonoska; Shiping Liao; Nadrian C. Seeman

2004-01-01

349

Cryptanalysis of Two Quartic Encryption Schemes and One Improved MFE Scheme  

Microsoft Academic Search

\\u000a MFE, a multivariate public key encryption scheme proposed by Wang et al in CT-RSA 2006, was conquered by second order linearization\\u000a equation (SOLE) attack by Ding et al in PKC 2007. To resist this attack, many improved schemes were proposed. Wang et al in\\u000a [WFW09 and Wang in [Wan07] both modified MFE and raised the public key from quadratic to

Weiwei Cao; Xiuyun Nie; Lei Hu; Xiling Tang; Jintai Ding

2010-01-01

350

Connecting your Apple to Octopus 7600's  

SciTech Connect

In UCID-19588, Communicating between the Apple and the Wang, we described how to take Apple DOS text files and send them to the Wang, and how to return Wang files to the Apple. It is also possible to use your Apple as an Octopus terminal, and to exchange files with Octopus 7600's. Presumably, you can also talk to the Crays, or any other part of the system. This connection has another virtue. It eliminates one of the terminals in your office.

Barton, G.W. Jr.

1983-01-17

351

77 FR 42730 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification...  

Federal Register 2010, 2011, 2012, 2013

...Entertainment Holdings, Inc.; Mr. Jianlin Wang. 20120934.................. G Starbucks Corporation; The Julie Lepinard Alpha Trust; Starbucks Corporation. 20120936.................. G Monsanto Company; Gregg...

2012-07-20

352

Work environment impact scale: Testing the psychometric properties of the Swedish version.  

PubMed

BACKGROUND: The Work Environment Impact Scale (WEIS) is an assessment that focuses on the fit between a person and his or her work environment. It is based on Kielhofner's Model of Human Occupation and designed to gather information on how clients experience their work environment. OBJECTIVE: The aim of this study was to examine the psychometric properties of the Swedish version of the WEIS assessment instrument. METHOD: In total, 95~ratings on the 17-item WEIS were obtained from a sample of clients with experience of sick leave due to different medical conditions. Rasch analysis was used to analyze the data. RESULTS: Overall, the WEIS items together cohered to form a single construct of increasingly challenging work environmental factors. The hierarchical ordering of the items along the continuum followed a logical and expected pattern, and the participants were validly measured by the scale. The three occupational therapists serving as raters validly used the scale, but demonstrated a relatively high rater separation index, indicating differences in rater severity. CONCLUSION: The findings provide evidence that the Swedish version of the WEIS is a psychometrically sound assessment across diagnoses and occupations, which can provide valuable information about experiences of work environment challenges. PMID:23324715

Ekbladh, Elin; Fan, Chia-Wei; Sandqvist, Jan; Hemmingsson, Helena; Taylor, Renée

2013-01-01

353

PREFACE: International Conference on Inverse Problems 2010  

NASA Astrophysics Data System (ADS)

Following the first International Conference on Inverse Problems - Recent Theoretical Development and Numerical Approaches held at the City University of Hong Kong in 2002, the fifth International Conference was held again at the City University during December 13-17, 2010. This fifth conference was jointly organized by Professor Yiu-Chung Hon (Co-Chair, City University of Hong Kong, HKSAR), Dr Leevan Ling (Co-Chair, Hong Kong Baptist University, HKSAR), Professor Jin Cheng (Fudan University, China), Professor June-Yub Lee (Ewha Womans University, South Korea), Professor Gui-Rong Liu (University of Cincinnati, USA), Professor Jenn-Nan Wang (National Taiwan University, Taiwan), and Professor Masahiro Yamamoto (The University of Tokyo, Japan). It was agreed to alternate holding the conference among the above places (China, Japan, Korea, Taiwan, and Hong Kong) once every two years. The next conference has been scheduled to be held at the Southeast University (Nanjing, China) in 2012. The purpose of this series of conferences is to establish a strong collaborative link among the universities of the Asian-Pacific regions and worldwide leading researchers in inverse problems. The conference addressed both theoretical (mathematics), applied (engineering) and developmental aspects of inverse problems. The conference was intended to nurture Asian-American-European collaborations in the evolving interdisciplinary areas and it was envisioned that the conference would lead to long-term commitments and collaborations among the participating countries and researchers. There was a total of more than 100 participants. A call for the submission of papers was sent out after the conference, and a total of 19 papers were finally accepted for publication in this proceedings. The papers included in the proceedings cover a wide scope, which reflects the current flourishing theoretical and numerical research into inverse problems. Finally, as the co-chairs of the Inverse Problems Conference 2010, we wish to express our cordial thanks to all the keynote, plenary, and invited speakers and members of the Advisory Board. We would like to thank the City University of Hong Kong, the Hong Kong Mathematical Society, the K C Wong Education Foundation, the Lee Hysan Foundation, and the Wei Lun Foundation for their generous financial support. Particularly, we wish to thank Miss Lonn Chan for her excellent administrative work in making all the arrangements for the conference. March 2011Yiu-Chung Hon, City University of Hong Kong, HKSARLeevan Ling, Hong Kong Baptist University, HKSAR Invited Keynote SpeakerH Thomas Banks, North Carolina State University, USA Invited Plenary SpeakersRyuichi Ashino, Osaka Kyoiku University, JapanAndrea Caponnetto, City University of Hong Kong, HKSARJeng-Tzong Chen, National Taiwan Ocean University, TaiwanHiromichi Itou, Gunma University, JapanHyeonbae Kang, Inha University, South KoreaMichael Klibanov, University of North Carolina at Charlotte, USAKim Knudsen, Technical University of Denmark, DenmarkRainer Kress, Georg-August-Universität Göttingen, GermanyJérôme Le Rousseau, University of Orleans, FranceChang-Ock Lee, Korea Advanced Institute of Science and Technology (KAIST), South KoreaGui-Rong Liu, University of Cincinnati, USAShuai Lu, Fudan University, ChinaFadil Santosa, University of Minnesota, USATomoya Takeuchi, North Carolina State University, USAXiang Xu, Zhejiang University, ChinaJun Zou, The Chinese University of Hong Kong, HKSAR Invited SpeakersMohamed Abdel-Mooty, The American University in Cairo, EgyptKrishna Agarwal, National University of Singapore, SingaporeHui Cao, Sun Yat-sen University, ChinaWen Chen, Hohai University, ChinaJin Cheng, Fudan University, ChinaLian Duan, University of Oxford, UKMeibao Ge, Zhejiang Sci-Tech University, ChinaRalf Hielscher, TU Chemnitz, GermanyGuanghui Hu, Weierstrass Institute for Applied Analysis and Stochastics (WIAS), GermanyKiwan Jeon, National Institute for Mathematical Sciences, South KoreaYu Jiang, Hokkaido University, JapanDe-Xing Kong, Zhejiang University, China

Hon, Yiu-Chung; Ling, Leevan

2011-03-01

354

Three new species of Pilea (Urticaceae) from limestone karst in China.  

PubMed

Three hitherto undescribed species of Pilea (Urticaceae) from limestone karst in China are described and illustrated. Affinities of the species are discussed and Global Species Conservation Assessments presented. The new species are Pilea cavernicola A.K. Monro, C.J. Chen & Y.G. Wei, sp. nov. (Vulnerable) which most closely resembles Pilea scripta (Buch.-Ham. ex D.Don) Wedd. and Pilea gracilis Handel-Mazzetti, Pilea shizongensis A.K. Monro, C.J. Chen & Y.G. Wei, sp. nov. (Endangered) which is most similar to Pilea aquarum Dunn and Pilea guizhouensis A.K. Monro, C.J. Chen & Y.G. Wei, sp. nov. (Vulnerable) which resembles Pilea boniana Gagnep. and Pilea rubriflora C. Wright mostclosely. PMID:23717190

Monro, Alex K; Wei, Y G; Chen, C J

2012-12-28

355

Yani: The Brush of Innocence. Teacher's Activity Packet, Grades One through Five.  

ERIC Educational Resources Information Center

|This document presents a teaching package designed to introduce students in grades one through five to Chinese painting methods and equipment. Prepared in conjunction with an exhibition of paintings by child prodigy Wang Yani titled "The Brush of Innocence," the package consists of a teacher's activity plan unit, a slide set of art works by Wang…

Smithsonian Institution, Washington, DC. Arthur M. Sackler Gallery.

356

Chromosome Image Enhancement Using Multiscale Differential Operators  

Microsoft Academic Search

Chromosome banding patterns are very important features for karyotyping, based on which cytogenetic diagnosis procedures are conducted. Due to cell culture, staining, and imaging conditions, image enhancement is a desirable prepro- cessing step before performing chromosome classification. In this paper, we apply a family of differential wavelet transforms (Wang and Lee, 1998), (Wang, 1999) for this purpose. The proposed differential

Yu-ping Wang; Qiang Wu; Kenneth R. Castleman; Zixiang Xiong

2003-01-01

357

Maxicalculators for the Whole School. Illinois Series on Educational Applications of Computers. Number 5.  

ERIC Educational Resources Information Center

A brief review is presented of the characteristics of four maxicalculators (HP 9830, Wang 2200, IBM 5100, MCM/700) and two minicomputers (Classic, Altair 8800). The HP 9830 and the Wang 2200 are thought to be the best adapted to serve entire schools and their unique properties are discussed. Some criteria of what should be taken into account in…

Doring, Richard; Hicks, Bruce

358

Hybrid Slip Model for Predicting Near-field Strong Ground Motion  

Microsoft Academic Search

A hybrid slip model combined an Asperity model and k-2 model for predicting near-field strong ground motion is proposed in this paper. Firstly, the asperity model charactering lower wave number of slip distribution is estimated based on works of Wang (2004), Wang and Tao (2004a, b). Secondly, k square slip model charactering higher wave number of slip distribution was determined

Haiyun Wang; Xiaxin Tao

359

A Comparison of Alternative Models for Testlets  

ERIC Educational Resources Information Center

|When tests are made up of testlets, standard item response theory (IRT) models are often not appropriate due to the local dependence present among items within a common testlet. A testlet-based IRT model has recently been developed to model examinees' responses under such conditions (Bradlow, Wainer, & Wang, 1999). The Bradlow, Wainer, and Wang…

Li, Yanmei; Bolt, Daniel M.; Fu, Jianbin

2006-01-01

360

Phonology Is Necessary, but Not Sufficient: A Rejoinder  

ERIC Educational Resources Information Center

|Paul, Wang, Trezek, and Luckner offer a rebuttal to an article by Allen, Clark, del Giudice, Koo, Lieberman, Mayberry, and Miller published in the same issue of the "American Annals of the Deaf" (Fall 2009) that is critical of an article by Wang, Trezek, Luckner, and Paul that was published in the Fall 2008 "Annals". Major themes from the article…

Paul, Peter V.; Wang, Ye; Trezek, Beverly J.; Luckner, John L.

2009-01-01

361

HRD Learning Participation: An Empirical Study of E-Learning Completion  

ERIC Educational Resources Information Center

|This study offers empirical evidence in HRD e-learning completion. Based on the Learning Participation Theory (LPT) (Wang & Wang, 2004), a study was conducted with U.S. corporate e-learners to explore the determinants of e-learning completion. The results generally confirmed the hypothesis by the LPT that individual, learning process, and…

Wang, Greg G.; Foucar-Szocki, Diane; Griffin, Oris

2006-01-01

362

Exercise during Pregnancy: What You Can Do for a Healthy Pregnancy  

MedlinePLUS

... vision Source Exercise During Pregnancy by Thomas W. Wang, M.D., and Barbara S. Apgar, M.D. (American ... 15, 1998, http://www.aafp.org/afp/980415ap/wang.html) Written by familydoctor.org editorial staff Reviewed/ ...

363

Nanoscale oscillatory fracture propagation in metallic glasses  

SciTech Connect

We describe the oscillatory crack propagation for small propagation velocities at the atomistic scale that was recently observed for brittle metallic glasses [G. Wang, Y.T. Wang, Y.H. Liu, M.X. Pan, D.Q. Zhao, W.H. Wang, Appl. Lett. 89 (2006) 121909; G. Wang, D.Q. Zhao, H.Y. Bai, M.X. Pan, A.L. Xia, B.S. Han, X.K. Xi, Y. Wu, W.H. Wang, Phys. Rev. Lett. 98 (2007) 235501]. Based on a simple model of crack propagation [Y. Braiman, T. Egami, Phys. Rev. E, 77 (2008) 065101(R)], we derived and analyzed expressions for the feature size, oscillation period, and maximum strain accumulated in the material.

Braiman, Yehuda [ORNL; Egami, T [University of Tennessee, Knoxville (UTK)

2009-01-01

364

Nanoscale oscillatory fracture propagation in metallic glasses  

NASA Astrophysics Data System (ADS)

We describe the oscillatory crack propagation for small propagation velocities at the atomistic scale that was recently observed for brittle metallic glasses [G. Wang, Y.T. Wang, Y.H. Liu, M.X. Pan, D.Q. Zhao, W.H. Wang, Appl. Lett. 89 (2006) 121909; G. Wang, D.Q. Zhao, H.Y. Bai, M.X. Pan, A.L. Xia, B.S. Han, X.K. Xi, Y. Wu, W.H. Wang, Phys. Rev. Lett. 98 (2007) 235501]. Based on a simple model of crack propagation [Y. Braiman, T. Egami, Phys. Rev. E, 77 (2008) 065101(R)], we derived and analyzed expressions for the feature size, oscillation period, and maximum strain accumulated in the material.

Braiman, Y.; Egami, T.

2009-05-01

365

Die Haftung des Wirtschaftsprüfers am Primärund am Sekundärmarkt — eine rechtsökonomische Analyse  

Microsoft Academic Search

Zusammenfassung??Inwieweit sollten Wirtschaftspr?fer f?r die Verm?genssch?den von Anlegern haften (Dritthaftung)? Ein fehlerhaftes Testat f?hrt oft zur ?berbewertung des Unternehmens. Auf dem Sekund?rmarkt wei? der Anleger ex-ante nicht, ob er K?ufer oder Verk?ufer ?berteuerter Aktien sein wird. Er kann einen Schaden erleiden, aber auch vom fehlerhaften Testat profitieren. Bei einem B?rsengang (Prim?rmarkt) wei? der Anleger hingegen ex-ante genau, dass er auf

Jochen Bigus; Hans-Bernd Schäfer

2007-01-01

366

EDITORIAL: Roberts Prize for the best paper published in 2009 Roberts Prize for the best paper published in 2009  

NASA Astrophysics Data System (ADS)

The publishers of Physics in Medicine and Biology (PMB), IOP Publishing, in association with the journal owners, the Institute of Physics and Engineering in Medicine (IPEM), jointly award an annual prize for the best paper published in PMB during the previous year. The procedure for deciding the winner has been made as thorough as possible, to try to ensure that an outstanding paper wins the prize. We started off with a shortlist of the 10 research papers published in 2009 which were rated the best based on the referees' quality assessments. Following the submission of a short 'case for winning' document by each of the shortlisted authors, an IPEM college of jurors of the status of FIPEM assessed and rated these 10 papers in order to choose a winner, which was then endorsed by the Editorial Board. We have a clear, and very worthy, winner this year. We have much pleasure in advising readers that the 2009 Roberts Prize is awarded to E Z Zhang et al from University College London for their paper on photoacoustic tomography. In vivo high resolution 3D photoacoustic imaging of superficial vascular anatomy E Z Zhang, J G Laufer, R B Pedley and P C Beard 2009 Phys. Med. Biol. 54 1035-46 Our congratulations go to these authors. Of course all of the shortlisted papers were of great merit, and the full top-10 is listed below (in alphabetical order). Steve Webb Editor-in-Chief Simon Harris Publisher References Cheng Y-C N , Neelavalli J and Haacke E M 2009 Limitations of calculating field distributions and magnetic susceptibilities in MRI using a Fourier based method Phys. Med. Biol. 54 1169-89 Cho S, Ahn S, Li Q and Leahy R M 2009 Exact and approximate Fourier rebinning of PET data from time-of-flight to non time-of-flight 2009 Phys. Med. Biol. 54 467-84 Davidson S R H, Weersink R A, Haider M A, Gertner M R, Bogaards A, Giewercer D, Scherz A, Sherar M D, Elhilali M, Chin J L, Trachtenberg J and Wilson B C 2009 Treatment planning and dose analysis for interstitial photodynamic therapy of prostate cancer Phys. Med. Biol. 54 2293-313 Hand J W, Shaw A, Sadhoo N, Rajagopal S, Dickinson R J and Gavrilov L R 2009 A random phased array device for delivery of high intensity focused ultrasound Phys. Med. Biol. 54 5675-93 Johnson P, Lee C, Johnson K, Siragusa D and Bolch W E 2009 The influence of patient size on dose conversion coefficients: a hybrid phantom study for adult cardiac catheterization Phys. Med. Biol. 54 3613-29 Paganetti H 2009 Dose to water versus dose to medium in proton beam therapy Phys. Med. Biol. 54 4399-421 Pramanik M, Song K H, Swierczewska M, Green D, Sitharaman B and Wang L V 2009 In vivo carbon nanotube-enhanced non-invasive photoacoustic mapping of the sentinel lymph node Phys. Med. Biol. 54 3291-301 Schöndube H, Stierstorfer K and Noo F 2009 Accurate helical cone-beam CT reconstruction with redundant data 2009 Phys. Med. Biol. 54 4625-44 Tang G, Earl M A and Yu C X 2009 Variable dose rate single-arc IMAT delivered with a constant dose rate and variable angular spacing Phys. Med. Biol. 54 6439-56 Zhang E Z, Laufer J G, Pedley R B and Beard P C 2009 In vivo high resolution 3D photoacoustic imaging of superficial vascular anatomy Phys. Med. Biol. 54 1035-46 For more information on this article see medicalphysicsweb.org

Webb, Steve; Harris, Simon

2010-07-01

367

Effects of traditional Chinese formulations on rat carotid artery injured by balloon endothelial denudation.  

PubMed

We examined the inhibitory effects of traditional Chinese formulations (TCFs: Kampo formulation in Japanese) on intimal thickening of the carotid artery injured by balloon endothelial denudation in rats. Among the eight TCFs examined oren-gedoku-to (huanglian-jiedu-tang in Chinese), choto-san (diao-teng-san), saiko-ka-ryukotsu-borei-to (chaihujia-longgu-muli-tang) and dai-joki-to (da-cheng-qi-tang) significantly inhibited the intimal thickening 7 days after denudation. These four TCFs also inhibited proliferation of vascular smooth muscle cells (VSMC), which may play a central role in the development of restenosis after balloon endothelial denudation. The present results suggest that further evaluation of these four TCFs as inhibitors of VSMC proliferation to prevent arteriosclerosis is warranted. PMID:12856859

Chung, Hwa-Jin; Kim, Dong-Wook; Maruyama, Ikuro; Tani, Tadato

2003-01-01

368

Theory of carrier mediated ferromagnetism in dilute magnetic oxides  

NASA Astrophysics Data System (ADS)

We analyze the origin of ferromagnetism as a result of carrier mediation in diluted magnetic oxide semiconductors in the light of the experimental evidence reported in the literature. We propose that a combination of percolation of magnetic polarons at lower temperature and Ruderman Kittel Kasuya Yosida ferromagnetism at higher temperature may be the reason for the very high critical temperatures measured (up to ˜700 K).PACS75.50.Pp75.30.Hx75.10.-bKeywordsMagnetic oxidesCarrier mediated ferromagnetismRKKYMagnetic polaron percolationReferencesI.Žuti?J.FabianS.Das SarmaRev. Mod. Phys.762004323J.K.FurdynaJ. Appl. Phys.641988R29D.FerrandJ.CibertA.WasielaC.BourgognonS.TatarenkoG.FishmanT.T.AndrearczykJ.Jaroszy?skiS.Kole?nikT.DietlB.BarbaraD.DufeuPhys. Rev. B632001085201H.MunekataH.OhnoS.von MolnarArminSegmallerL.L.ChangL.EsakiPhys. Rev. Lett.6319891849H.OhnoH.MunekataT.PenneyS.von MolnarL.L.ChangPhys. Rev. Lett.6819922664H.OhnoA.ShenF.MatsukuraA.OiwaA.EndoS.KatsumotoY.IyeAppl. Phys. Lett.691996363T.JungwirthJ.SinovaJ.MasekJ.KuceraA.H.MacDonaldRev. Mod. Phys.782006809K.Y. Wang, K.W. Edmonds, R.P. Campion, L.X. Zhao, A.C. Neumann, C.T. Foxon, B.L. Gallagher, P.C. Main in: Proceedings of the ICPS-26 (IOP,UK), 2002, p. 58.K.W.EdmondsK.Y.WangR.P.CampionA.C.NeumannN.R.S.FarleyB.L.GallagherC.T.FoxonAppl. Phys. Lett.8120024991D.ChibaK.TakamuraF.MatsukuraH.OhnoAppl. Phys. Lett.8220033020R.JanischP.GopalN.A.SpaldinJ. Phys.: Condens. Matter172005R657Y.MatsumotoM.MurakamiT.ShonoT.HasegawaT.FukumuraM.KawasakiP.AhmetT.ChikyowS.KoshiharaH.KoinumaScience2912001854K.UedaH.TabataT.KawaiAppl. Phys. Lett.792001988S.B.OgaleR.J.ChoudharyJ.P.BubanS.E.LoflandS.R.ShindeS.N.KaleV.N.KulkarniJ.HigginsC.LanciJ.R.SimpsonN.D.BrowningS.Das SarmaH.D.DrewR.L.GreeneT.VenkatesanPhys. Rev. Lett.912003077205S.R.ShindeS.B.OgaleS.Das SarmaJ.R.SimpsonH.D.DrewS.E.LoflandC.LanciV.N.KulkarniJ.HigginsR.P.SharmaR.L.GreeneT.VenkatesanPhys. Rev. B672003115211L.ForroO.ChauvetD.EminL.ZuppiroliH.BergerF.LevyJ. Appl. Phys.751994633H.TangK.PrasadR.SanjinesP.E.SchmidF.LevyJ. Appl. Phys.7519942042H.ToyosakiT.FukumuraY.YamadaK.NakajimaT.ChikyowT.HasegawaH.KoinumaM.KawasakiNature Mater.32004221M.VenkatesanC.B.FitzgeraldJ.G.LunneyJ.M.D.CoeyPhys. Rev. Lett.932004177206S.A.ChambersS.M.HealdT.DroubayPhys. Rev. B672003100401(R)T.ZhaoS.R.ShindeS.B.OgaleH.ZhengT.VenkatesanR.RameshS.Das SarmaPhys. Rev. Lett.942005126601S.R.ShindeS.B.OgaleJ.S.HigginsH.ZhengA.J.MillisV.N.KulkarniR.RameshR.L.GreeneT.VenkatesanPhys. Rev. Lett.922004166601J.D.BryanS.M.HealdS.A.ChambersD.R.GamelinJ. Am. Chem. Soc.126200411640H.ToyosakiT.FukumuraY.YamadaM.KawasakiAppl. Phys. Lett.862005182503J.W.QuiltyA.ShibataJ.-Y.SonK.TakuboT.MizokawaH.ToyosakiT.FukumuraM.KawasakiPhys. Rev. Lett.962006027202C.N.R.RaoF.L.DeepakJ. Mater. Chem.152005573and references thereinN.A.SpaldinPhys. Rev. B692004125201K.RodeA.AnaneR.MattanaJ.-P.ContourO.DurandR.LeBourgeoisJ. Appl. Phys.9320037676A.DiniaG.SchmerberV.Pierron-BohnesC.MnyP.PanissodE.BeaurepaireJ. Magn. Magn. Mater.286200537H.-T.LinT.-S.ChinJ.-C.ShihS.-H.LinT.-M.HongR.-T.HuangF.-R.ChenJ.-J.KaiAppl. Phys. Lett.852004621K.AndoH.SaitoZ.JinT.FukumuraM.KawasakiY.MatsumotoH.KoinumaAppl. Phys. Lett.7820012700J. Appl. Phys. 89, 7284 (2001)J.R.NealA.J.BehanR.M.IbrahimH.J.BlytheM.ZieseA.M.FoxG.A.GehringPhys. Rev. Lett.962006197208K.R.KittilstvedD.A.SchwartzA.C.TuanS.M.HealdS.A.ChambersD.R.GamelinPhys. Rev. Lett.972006037203J.M.D.CoeyA.P.DouvalisC.B.FitzgeraldM.VenkatesanAppl. Phys. Lett.8420041332K.L.ChopraS.MayorD.K.PandyaThin Solid Films10219831T.DietlSemicond. Sci. Technol.172002377C.TimmJ. Phys.: Condens. Matter152003R1865S.Das SarmaE.H.HwangA.KaminskiSolid State Commun.127200399A.H.MacDonaldP.SchifferN.SamarthNature Mater.42005195A.ChattopadhyayS.Das SarmaA.J.MillisPhys. Rev. Lett.872001227202M.J.CalderónG.Gómez SantosL.BreyPhys. Rev. B662002075218A.KaminskiS.Das SarmaPhys. Rev. Lett.882002247202D.J.PriourJr.E.H.HwangS.Das SarmaPhys. Rev. Lett.922004117201C.ZenerPhys. Rev.821951403405J.S.HigginsS.R.ShindeS.B.OgaleT.VenkatesanR.L.GreenePhys. Rev. B692004073201D.J.PriourS.Das Sa

Calderón, M. J.; Das Sarma, S.

2007-11-01

369

TFBS identification based on genetic algorithm with combined representations and adaptive post-processing  

Microsoft Academic Search

Motivation: Identification of transcription factor binding sites (TFBSs) plays an important role in deciphering the mechanisms of gene regulation. Recently, GAME (Wei and Jensen, 2006), a Genetic Algorithm (GA) based approach with iterative post-processing, has shown superior performance in TFBS identification. However, the basic GA in GAME is not elaborately designed, and may be trapped in local optima in real

Tak-ming Chan; Kwong-sak Leung; Kin-hong Lee

2008-01-01

370

77 FR 44310 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G  

Federal Register 2010, 2011, 2012, 2013

...J. BETZ-VAIS KLAUS BI JEFF HUA BI WEI LI BLENKERS TED BODMER ANDREA ISABELLE BRINGOLF...ALDRICH GODFREY SEAN MICHAEL GOH DENISE SU-LI GOLD MARVIN BENJAMIN GONG CHENGQIAN GRENIER...KATIE LEE WENDY WAI SHUM LEUNG KING ANSELM LI ADRIENNE MAY LI JEREMY YUEN LIM...

2012-07-27

371

School-based sports participation and its effects on weight maintenance in Mexican American adolescents: A two-year analysis  

Technology Transfer Automated Retrieval System (TEKTRAN)

Participation in sports has been shown to decrease standardized body mass index (zBMI), especially in school settings. Few studies have examined the impact of sports participation in a Mexican American sample. The purpose of this investigation was to examine the effect of sports participation on wei...

372

Remote Control System of Artificial Fish School and Its Fast Implementation  

Microsoft Academic Search

In our previous work, we have developed an interactive system of artificial fish school for Visual Marine Museum in Hisashi Kawabayashi and Yen-Wei Chen (2009), Kanami Kobayashi (2005), Craig W. Reynolds (1987). In this paper, we focus our researches on its fast implementation and remote control. We propose to use parallel processing techniques and space blocking method for fast implementation.

H. Kawabayashi; M. Khazab; J. Tweedale; L. C. Jain; Y.-W. Chen

2009-01-01

373

Subcontracting and Supplier Innovativeness in a Developing Economy: Evidence from China's Information and Communication Technology Industry  

Microsoft Academic Search

Sun Y., Zhou Y., Lin G. C. S. and Wei Y. H. D. Subcontracting and supplier innovativeness in a developing economy: evidence from China's information and communication technology industry, Regional Studies. This study critically evaluates the relevance of the global value chains theory against the actual practices of subcontracting and technological innovation in China based on a large-scale empirical firm

Yifei Sun; Yu Zhou; George C. S. Lin; Y. H. Dennis Wei

2011-01-01

374

Needs and Opportunities for Uncertainty Based Multidisciplinary Design Methods for Aerospace Vehicles  

Microsoft Academic Search

Abstract: this report: GovindChanani, Wei Chen, Raymond Cosner, Evin Cramer, William Follett, Glenn Havskjold, Han-Pin Kan, GeorgeKarniadakis, Sallie Keller-McNulty, Jerry Lockenour, Mary Mahler, William Oberkampf, Raj Rajagopal, MunirSindir, Alyson Wilson, and Rudy Yurkovich

Thomas A. Zang; Michael J. Hemsch; Mark W. Hilburger; Sean P. Kenny; James M. Luckring; Peiman Maghami; Sharon L. Padula; W. Jefferson Stroud

2002-01-01

375

Semantic Prosody and ESL/EFL Vocabulary Pedagogy  

ERIC Educational Resources Information Center

|There is evidence that semantic prosody, a novel linguistic theme, should attract much attention in ESL/EFL (English as a second/foreign language) vocabulary learning and teaching. Research suggests that inappropriate word choice arising from ignorance of semantic prosody is common among ESL/EFL learners (Wei, 2006; Xiao & McEnery, 2006). This…

Zhang, Weimin

2009-01-01

376

The Ellen DeGeneration: Nudging Bias in the Creative Arts Classroom  

ERIC Educational Resources Information Center

|Research in the areas of lesbian, gay, bisexual, trans and queer (LGBTQ) issues in education has been growing steadily over the past 10 years with the help of Fine and Weis ("Silenced voices and extraordinary conversations: re-imagining schools," 2003), Rasmussen ("Becoming subjects: sexualities and secondary schooling," 2006), Tolman ("Dilemmas…

Harris, Anne

2013-01-01

377

Optimality test for generalized FCM and its application to parameter selection  

Microsoft Academic Search

In cluster analysis, the fuzzy c-means (FCM) clustering algorithm is the best known and most widely used method. It was proven to converge to either a local minimum or saddle points by Bezdek et al. Wei and Mendel produced efficient optimality tests for FCM fixed points. Recently, a weighting exponent selection for FCM was proposed by Yu et al. Inspired

Jian Yu; Miin-shen Yang

2005-01-01

378

RFID Security: Tradeoffs between Security and Efficiency  

Microsoft Academic Search

We propose a model and definition for anonymous (group) identification that is well suited for RFID systems. This is based on the definition of Juels and Weis of strong privacy for RFID tags, where we add requirements for completeness and soundness. We also propose a weaker and more realistic definition of privacy. For the case where tags hold independent keys,

Ivan Damgård; Michael Østergaard Pedersen

2008-01-01

379

Generalized Hamming Weights of Convolutional Codes.  

National Technical Information Service (NTIS)

Motivated by applications in cryptology K. Wei introduced in 1991 the concept of a generalized hamming weight for a linear block code. In this paper the authors define generalized Hamming weights for the class of convolutional codes and they derive severa...

J. Rosenthal E. V. York

1995-01-01

380

DEVELOPING A PREDICTIVE SIMULATION MODEL FOR ANTIANDROGEN IMPACTS ON RODENT PROSTATE  

EPA Science Inventory

Developing a predictive simulation model for antiandrogen impacts on rodent prostate HA Barton1, RW Setzer1, LK Potter1,2 1US EPA, ORD, NHEERL, ETD, PKB, Research Triangle Park, NC and 2Curriculum in Toxicology, UNC, Chapel Hill, NC Alterations in rodent prostate wei...

381

Construction Sites: Excavating Race, Class, and Gender among Urban Youth. The Teaching for Social Justice Series.  

ERIC Educational Resources Information Center

This book presents a collection of papers on the lives of urban youths in and out of school. There are 17 chapters in 4 parts. Part 1, "Spaces for Identity Work," includes: (1) "Writing on the Bias" (Linda Brodkey); (2) "Learning to Speak Out in an Abstinence-Based Sex Education Group: Gender and Race Work in an Urban Magnet School" (Lois Weis and…

Weis, Lois, Ed.; Fine, Michelle, Ed.

382

DIVERGENT SELECTION FOR TOTAL FLEECE WEIGHT IN THE ADULT ANGORA RABBIT: DIRECT RESPONSE TO SELECTION ON TOTAL FLEECE WEIGHT AT FIRST AND SECOND HARVEST  

Microsoft Academic Search

In order to explore genetic variability of wool pro duction and other quantitative traits, an 8-cohort divergent selection experiment for total fleece wei ght (TFW) was carried out in French Angora rabbits. Studies were made on the wool production o f a total of 669 female rabbits born between 1994 and 2001 and having produced wool from first to 12

383

Texture synthesis over arbitrary manifold surfaces  

Microsoft Academic Search

Algorithms exist for synthesizing a wide variety of textures over rectangular domains. However, it remains difficult to synthesize general textures over arbitrary manifold surfaces. In this paper, we present a solution to this problem for surfaces defined by dense polygon meshes. Our solution extends Wei and Levoy's texture synthesis method [25] by generalizing their definition of search neighborhoods. For each

Li-Yi Wei; Marc Levoy

2001-01-01

384

Effects of Commercial Fishing on the Population of Smallmouth Buffalo, 'Ictiobus bubalus' (Rafinesque), in Elephant Butte Lake, New Mexico.  

National Technical Information Service (NTIS)

Studies were made on several parameters of the population of smallmouth buffalo in Elephant Butte Lake, New Mexico. Results are compared with similar studies made prior to April 1968, to determine influences caused by commercial removal of 95,640 fish wei...

T. M. Moody

1970-01-01

385

November 29, 2012: Cellular, Tissue and Gene Therapies ...  

Center for Biologics Evaluation and Research (CBER)

... 1.9MB) Andrew Byrnes, PhD; Carolyn Wilson, PhD; Suzanne Epstein, PhD; Graeme Price, PhD; Jakob Reiser, PhD; Wu Ou, MD; Cheng-Hong Wei ... More results from www.fda.gov/advisorycommittees/committeesmeetingmaterials/bloodvaccinesandotherbiologics

386

K-RAS MUTATIONS IN LUNG CARCINOMAS FROM NONSMOKING WOMEN EXPOSED TO UNVENTED COAL SMOKE IN CHINA  

EPA Science Inventory

Abstract Lung cancer mortality rate in nonsmoking women in Xuan Wei (XW) County is the highest in China. The XW lung cancer rate is associated with exposure to coal smoke, containing high concentrations of polycyclic aromatic hydrocarbons (PARs), in unvented homes. Here we restig...

387

Canadian Libraries and Mass Deacidification.  

ERIC Educational Resources Information Center

|Considers the advantages and disadvantages of six mass deacidification processes that libraries can use to salvage printed materials: the Wei T'o process, the Diethyl Zinc (DEZ) process, the FMC (Lithco) process, the Book Preservation Associates (BPA) process, the "Bookkeeper" process, and the "Lyophilization" process. The availability of these…

Pacey, Antony

1992-01-01

388

INDOOR AIR SAMPLING AND MUTAGENICITY STUDIES RELATED TO EMISSIONS FROM UNVENTED COAL COMBUSTION  

EPA Science Inventory

The purpose of the study is to develop sampling strategies and bioassay methods for indoor air in homes. The work reported here was conducted to prepare for a joint U.S.-China field study in Xuan Wei County, Yunnan Province, southern China, where the residents traditionally burn ...

389

FULL-SCALE LABORATORY SIMULATION FACILITY TO TEST PARTICULATE AND ORGANIC EMISSIONS FROM A THIRD WORLD RESIDENTIAL COMBUSTION PROCESS. III. EVALUATIO OF A POTENTIAL TECHNIQUE FOR THE CONTROL OF EMISSIONS FROM THE INDOOR, OPEN HEARTH COMBUSTION OF COAL  

EPA Science Inventory

The paper reports controlled full-scale laboratory studies designed to determine if clay addition holds promise as a technique to control emissions from higher grade coals. NOTE: bnormally high rates of lung cancer are observed among persons in Xuan Wei County, China, who burn bi...

390

Positive family relationships and religious affiliation as mediators between negative environment and illicit drug symptoms in American Indian adolescents  

Microsoft Academic Search

The present study tests how positive family relationships and religious affiliation mediate between negative familial and social environments, and adolescent illicit drug abuse\\/dependence symptoms. The theoretical framework is based on an integration of two theories: the ecological model of human development (Bronfenbrenner, 1979) and the social development model (Hawkins & Weis, 1985). We used a stratified random sample of 401

ManSoo Yu; Arlene R. Stiffman

2010-01-01

391

A new species of Zygnemopsis (zygnemataceae) and its reproduction cycles  

NASA Astrophysics Data System (ADS)

The morphology and reproduction cycles of a new species, Zygnemopsis hubeiensis Wei are described and illustrated for a culture homothallic strain collected from Wuhan, Hubei, China. The asexual reproduction is by parthenospores, aplanospores and akinetes. The major events of the sexual cycle, including the genuflection of reproductive cells, gametangial development, gamete formation, gamete fusion, zygote formation, zygospore development, and zygospore germination are observed.

Wei, Yin-Xin

1994-06-01

392

Stabilized Calcium Acetate Oil Dispersions.  

National Technical Information Service (NTIS)

A lubricating composition is imparted with improved load-carrying ability and anti-wear properties by incorporation of calcium acetate. The composition consists of a base lubricant, 0.1 to 50 percent by weight calcium acetate and 0.01 to 20 percent by wei...

R. H. Davis

1965-01-01

393

INTERNAL DOSE AND RESPONSE IN REAL-TIME.  

EPA Science Inventory

Abstract: Rapid temporal fluctuations in exposure may occur in a number of situations such as accidents or other unexpected acute releases of airborne substances. Often risk assessments overlook temporal exposure patterns under simplifying assumptions such as the use of time-wei...

394

US EPA, Pesticide Product Label, GUARDSMAN MAX ...  

EPA Pesticide Factsheets

... lrlon ;:;' utec: ;)1", ? u.", "fl ,ny ~IPE Ill,l! Wei'S WCJlf' In tfW tr,) :!eU ,-!f~:~ :;t-'t, "t ·;.:·rl:f-'rlr:(j tht-' c~;LJ, elf':,; ? stort-' ,lil ... laddok' S-12 ? libeny" ·lightning' , ...

2011-04-21

395

Forecasting Conflict in the Balkans using Hidden Markov Models  

Microsoft Academic Search

This study uses hidden Markov models (HMM) to forecast conflict in the former Yugoslavia for the period January 1991 through January 1999. The political and military events reported in the lead sentences of Reuters news service stories were coded into the World Events Interaction Survey (WEIS) event data scheme. The forecasting scheme involved randomly selecting eight 100-event “templates” taken at

Philip A. Schrodt

396

Do Three Trade Blocs Minimize World Welfare?  

Microsoft Academic Search

Two interesting results have emerged from research on symmetric models that make the analysis of bilateralism tractable. Krugman reported that three trade blocs minimize world welfare. Frankel, Stein, and Wei argued that the formation of continental trading blocs can reduce welfare. This paper shows that these results are not robust. In particular, it is argued that the inclusion of more

Volker Nitsch

1996-01-01

397

Amylin Deposits in the Brain May Link Dementia and Diabetes  

MedlinePLUS

... Jorg J. Influence of Age on CD4 T Memory Cells DAB 1R13AG046016-01 Hiebert, Scott W. FASEB ... 1F31AG043222-01A1 Shaw, Laura Transcriptional Regulation of Immunological Memory DAB 1R01AG045761-01 Shen, Wei Contribution of Organ ...

398

Attributes and National Behavior, Part 2: Modern International Relations Monograph Series. Distance Theory, Results for Cooperation, 1966-69, An Inventory of Findings.  

ERIC Educational Resources Information Center

|This monograph is a computer printout which presents a summary of a study in which distance theory was applied to World Event Interaction Survey (WEIS) conflict data to determine how conflict and cooperation flow in international relations systems. The specific focus of the study was on cooperative political, economic, cultural, and commercial…

Vincent, Jack E.

399

Generalized Localized Matter Wavepackets  

Microsoft Academic Search

Studying the system of the non-Hermitian (NH) generalized parametric oscillator, we use the Wei-Norman factorization method, as well as the biorthonormal basis formalism, in order to initiate a complex probability density. Generalizing the usual Yuen procedure for the calculation of the variances Deltaq, Deltap in terms of the complex probability density, we obtain a reduction in the position and an

S. Baskoutas

1997-01-01

400

Variable structure control of discrete system with time-delay  

Microsoft Academic Search

A new discrete reaching law which is true of the ldquosix charactersrdquo given by Gao Wei-Bing is introduced in this paper. Then the control law is designed by using the discrete reaching law, and the method how to design a variable structure control of discrete system with time-delay is also introduced; It is manifested that the discrete control system with

De-Wen Zhou; Cun-Chen Gao

2008-01-01

401

Parental influence on eating behavior: Conception to adolescence  

Technology Transfer Automated Retrieval System (TEKTRAN)

The first years of life mark a time of rapid development and dietary change, as children transition from an exclusive milk diet to a modified adult diet. During these early years, children's learning about food and eating plays a central role in shaping subsequent food choices, diet quality, and wei...

402

Damage Mechanics Based Fatigue Life Prediction for 63Sn-37Pb Solder Materials.  

National Technical Information Service (NTIS)

This paper presents a method of TMF analysis based on the theory of damage mechanics to examine the fatigue damage accumulation in 63 Sn-37Pb solder. The method is developed by extending a viscoplastic damage model proposed earlier by the authors (Wei, et...

Y. Wei C. L. Chow M. K. Neilsen H. E. Fang

2000-01-01

403

Productivity Effects of United States Multinational Enterprises: The Roles of Market Orientation and Regional Integration  

Microsoft Academic Search

Smeets R. and Wei Y. Productivity effects of United States multinational enterprises: the roles of market orientation and regional integration, Regional Studies. This paper considers the role of market orientation and regional integration in foreign direct investment (FDI) productivity effects. Using data of United States multinational enterprises operating in eight industries and thirteen Organisation for Economic Co-operation and Development (OECD)

Roger Smeets; Yingqi Wei

2010-01-01

404

Improved algorithmic methods for the prediction of wavefront propagation behavior in multiconductor transmission lines for high frequency digital signal processors  

Microsoft Academic Search

Several computer-aided design (CAD) tools suitable for use by the designers of digital signal and data processors based on the quasi-TEM assumption for multiconductor transmission lines are presented. The integral equation method due to C. Wei, et al. (1984) is selected for the evaluation of electrostatic parameters, including capacitance, inductance, conductance, and resistance matrices, and attenuation factors as well as

Guang-wen Pan; Kenneth S. Olson; Barry K. Gilbert

1989-01-01

405

3 CFR 8779 - Proclamation 8779 of March 1, 2012. Irish-American Heritage Month, 2012  

Code of Federal Regulations, 2013 CFR

...Proc. 8779 Irish-American Heritage Month, 2012By...spirit of those Irish Americans whose strength helped...America worthy of the journey they and so many others...taken. During Irish-American Heritage Month, we...I have hereunto set my hand this first day...

2013-01-01

406

Novel approaches concerning catalyst deactivation. Final report, July 1, 1982-December 31, 1983  

SciTech Connect

A complete analysis is presented of a model originally suggested by Wei and Wei (J. Wei and R.G. Wei, Metal Deposition Profiles in Hydro-Demetallation, Chem. Eng. Comm., 13, 251, 1982) to model the behavior of catalysts during hydro-demetallation of coal derived liquids. This model does not take into account the fact that as hydro-demetallation reaction precedes the deposited metals deactivate the catalyst and destroy its pore structure. It was felt however that a complete analysis of this model was needed since it is amenable to analytical solutions, describes the initial state of more complete deactivation models and qualitatively predicts all the different metal profiles one expects to find on spent (deactivated) catalysts. The investigators have also presented here the set of equations describing a more complete and realistic hydro-demetallation model. The analysis of this model, however has yet to be completed and will be presented later as an addendum to this report. 7 references, 7 figures, 2 tables.

Tsotsis, T.T.

1984-03-01

407

NEUROBEHAVIORAL EVALUATION OF RATS EXPOSED TO CHLORPYRIFOS VIA CHRONIC DIETARY AND REPEATED HIGH-LEVEL SPIKE EXPOSURE.  

EPA Science Inventory

This study aimed to model long-term subtoxic human exposure to an organophosphorus pesticide, chlorpyrifos (CPF), and to examine the influence of that exposure on the response to intermittent high-dose acute challenges. Adult Long-Evans male rats were maintained at 350g body wei...

408

Class, Race, and Gender in American Education.  

ERIC Educational Resources Information Center

|This volume of essays on class, race, and gender in American education contains an introduction by Lois Weis. Cameron McCarthy and Michael W. Apple contributed an overview, "Race, Class, and Gender in American Educational Research: Toward a Nonsynchronous Parallelist Position." The book has two parts. Part 1, "Different Knowledge, Unequal…

Weis, Lois, Ed.

409

New material: a novella, and the accompanying exegesis, How to log into the book: cyborgs and fiction  

Microsoft Academic Search

The novella New Material explores the intersections between fictional space, cyber space and mythic space, through three characters’ narratives: Jo, his cousin Mei and Lee Wei Hong. Set in Singapore in 2007, the novella is narrated by each of these characters, whose voices interrupt and layer one another’s stories. Jo is a teen hacker and computer expert who lives fully

Lucy Alexander

2007-01-01

410

Teaching Absolute Value Meaningfully  

ERIC Educational Resources Information Center

|What is the meaning of absolute value? And why do teachers teach students how to solve absolute value equations? Absolute value is a concept introduced in first-year algebra and then reinforced in later courses. Various authors have suggested instructional methods for teaching absolute value to high school students (Wei 2005; Stallings-Roberts…

Wade, Angela

2012-01-01

411

Construction Sites: Excavating Race, Class, and Gender among Urban Youth. The Teaching for Social Justice Series.  

ERIC Educational Resources Information Center

|This book presents a collection of papers on the lives of urban youths in and out of school. There are 17 chapters in 4 parts. Part 1, "Spaces for Identity Work," includes: (1) "Writing on the Bias" (Linda Brodkey); (2) "Learning to Speak Out in an Abstinence-Based Sex Education Group: Gender and Race Work in an Urban Magnet School" (Lois Weis…

Weis, Lois, Ed.; Fine, Michelle, Ed.

412

Scaling laws with current for equilibrium momentum spread and emittances from intrabeam scattering and electron cooling  

Microsoft Academic Search

Based on the theories of Piwinski, Bjorken–Mtingawa and Martini of Coulomb scattering, expressions for the heating rates due to intrabeam scattering were known since a long time. Simplifications by Wei–Parzen and Rao and Piwinski led to analytic approximations which are easily applicable to existing lattices. We use these approximations and also the formulae from thermal equilibration of Struckmeier and equate

R. W. Hasse; O. Boine-Frankenheim

2004-01-01

413

A Qualitative Study of Language Beliefs and Linguistic Knowledge in Preservice Teachers Using the Intercultural Communicative Competence Framework  

ERIC Educational Resources Information Center

|Since 1980, the number of people in the United States who speak a language other than English at home has increased by 140% (United States Census Bureau, 2010). Therefore a greater percentage of students now are multilingual. Throughout the world, multilingualism is considered the norm and monolingualism is the exception (Auer & Wei, 2008). In…

Ilosvay, Kimberly K.

2012-01-01

414

Positioning and Repositioning: Linguistic Practices and Identity Negotiation of Overseas Returning Bilinguals in Hong Kong  

ERIC Educational Resources Information Center

|Li Wei (1995) notes that relatively little sociolinguistic work on bilingualism has attempted to analyze and compare the complex relationships between aspects of language choice and code-switching among subgroups of the same community. This study aims to investigate the co-existence of two structurally different Cantonese-English code-switching…

Chen, Katherine Hoi Ying

2008-01-01

415

Reconstructing northern Chinese Neolithic subsistence practices by isotopic analysis  

Microsoft Academic Search

Stable isotope signatures of both human and non-human animal bone samples indicate that Neolithic farmers of the Yellow and Wei River basins in China potentially cultivated millet for two reasons: as a staple for human consumption and as fodder for domesticated animals, specifically pigs, dogs, and perhaps chicken. Bone samples were analyzed from four Neolithic sites: Jiangzhai, Shijia, Xipo, and

Ekaterina A. Pechenkina; Stanley H. Ambrose; Ma Xiaolin; Robert A. Benfer

2005-01-01

416

Dynamic Photorefractive Optical Memories.  

National Technical Information Service (NTIS)

The extremely large storage density of volume holographic memories is applicable to numeric and neural network optical computing. Such photorefractive memories, can be used to provide optical storage of binary bit-plane or gray scale images as well as wei...

1992-01-01

417

US EPA, Pesticide Product Label, VARCO RESISTANT ...  

EPA Pesticide Factsheets

... e~:I'ilT(!·' . II: ,tcl'S .. ..-to 're II\\St'cts hd, tllnd f ,t! .. " . Itl weI ""prl:l\\ ... ~ 1· , Hi,;,! ... IJr 'A·h .... rever fh.·",, f!cts , ?. ' 11'('1 IJ,~ ro('PI A:~·) trelt t "lr! .? ...

2011-04-14

418

EXPOSURE TO DIETHYL HEXYL PHTHALATE (DEHP) DELAYS PUBERTY AND REDUCES ANDROGEN-DEPENDENT TISSUE WEIGHTS IN LONG EVANS HOODED AND SPRAGUE DAWLEY MALE RATS  

EPA Science Inventory

DEHP is a plasticizer that alters sexual differentiation in the male rat by reducing fetal Leydig cell testosterone synthesis and insl3 mRNA levels. When exposure includes the pubertal stage of life, DEHP and other phthalates delay puberty and reduce androgen-dependent tissue wei...

419

Secure frameproof codes, key distribution patterns, group testing algorithms and related structures  

Microsoft Academic Search

Frameproof codes were introduced by Boneh and Shaw as a method of “digital fingerprinting” which prevents a coalition of a specified size c from framing a user not in the coalition. Stinson and Wei then gave a combinatorial formulation of the problem in terms of certain types of extremal set systems. In this paper, we study frameproof codes that provide

D. R. Stinson; Tran van Trung; R. Wei

2000-01-01

420

Secure Frameproof Codes, Key Distribution Patterns, Group Testing Algorithms and Related Structures  

Microsoft Academic Search

Frameproof codes were introduced by Boneh and Shaw as a method of "digitalfingerprinting" which prevents a coalition of a specified size c from framing a user notin the coalition. Stinson and Wei then gave a combinatorial formulation of the problemin terms of certain types of extremal set sytems.In this paper, we study frameproof codes that provide a certain (weak) form

D. R. Stinson; Tran Van Trung; R. Wei

1997-01-01

421

Opportunities and Challenges of Bilingualism. Contributions to the Sociology of Language.  

ERIC Educational Resources Information Center

|This collection of papers examines, from an international perspective, opportunities and challenges of societal bilingualism in the new millennium. The 18 papers include the following: "Introduction: Opportunities and Challenges of Bilingualism" (Li Wei, Jean-Marc Dewaele, and Alex Housen); "'Holy Languages' in the Context of Societal…

Wei, Li, Ed.; Dewaele, Jean-Marc, Ed.; Housen, Alex, Ed.

422

MILK YIELD OF BEEF HEIFERS FROM THREE CALVING SYSTEMS  

Technology Transfer Automated Retrieval System (TEKTRAN)

In a 2-yr study, first-calf heifers from three calving systems were used to study milk yield throughout a 190-d lactation. Calving occurred in late January to late February (Feb calving), mid-March to mid-April (Apr calving), and mid-May to mid-June (Jun calving). Milk production was measured by wei...

423

The stranger that is welcomed: female foreign students from Asia, the English language industry, and the ambivalence of ‘Asia rising’ in British Columbia, Canada  

Microsoft Academic Search

In 2002, attacks on six Asian women and girls temporarily living in the Greater Vancouver Area, Canada to study the English language garnered significant attention. Beginning with the attempted murder of Korean national Ji-Won Park, and ending with the murder of Chinese national Wei Amanda Zhao, the attacks on Asian females sparked a national debate about the vulnerability of foreign

2010-01-01

424

Exploring generalized probability weighted moments, generalized moments and maximum likelihood estimating methods in two-parameter Weibull model  

Microsoft Academic Search

Generalized probability weighted moments (GPWM), generalized moments and maximum likelihood (ML) estimating methods are investigated in the two-parameter Weibull (WEI) model. Point estimators for positive and negative shape parameters and for quantiles with special return periods are derived. Analytical expressions for the asymptotic variances of the estimators are presented. Simulation results on the performance of the three estimating methods are

Smail Mahdi; Fahim Ashkar

2004-01-01

425

In vitro anti-microbial and in vivo cytokine modulating effects of different prepared Chinese herbal medicines  

Microsoft Academic Search

The toxicity, antimicrobial and cytokine modulating effects of herbal medicines in treating periodontal diseases were evaluated in this study. Using the broth dilution method and disc agar diffusion test, in individual and combined decocted preparations, different concentrations of Ching–Wei–San and its individual herbal components, Coptidis rhizoma, Angelicae sinensis radix, Rehmanniae radixet rhizom, Moutan radicis cortex, and Cimicifuga foetida, were tested

Shyh-Jye Lin; Chung-Shih Chen; Shih-Shen Lin; Ming-Yung Chou; Hung-Che Shih; I-Pang Lee; Chia-Tze Kao; Chuan-Chen Ho; Fong-Lin Chen; Yung-Chyuan Ho; Kuang-Hui Hsieh; Chi-Ruei Huang; Chi-Chiang Yang

2006-01-01

426

Analysis of the ancient river system in Loulan period in Lop Nur region  

Microsoft Academic Search

The Lop Nur region is located in the east of the Tarim Basin. It has served as the strategic passage and communication hub of the Silk Road since Han Dynasty. During Wei-Jin period, the river system there was well developed and the ancient city of Loulan was bred there. In this study, GIS is used to accomplish automatic extraction of

Jianfeng Zhu; Peng Jia; Yueping Nie

2010-01-01

427

Computational fluid dynamics (CFD) modeling of spouted bed: Influence of frictional stress, maximum packing limit and coefficient of restitution of particles  

Microsoft Academic Search

Following the previous article [Du, W., Bao, X., Xu, J., Wei, W., 2006. Computational fluid dynamics (CFD) modeling of spouted bed: assessment of drag coefficient correlations. Chemical Engineering Science 61 (5), 1401–1420], this contribution describes the influences of the frictional stress, maximum packing limit and coefficient of restitution of particles on CFD simulation of spouted beds. Using the two-fluid method

Wei Du; Xiaojun Bao; Jian Xu; Weisheng Wei

2006-01-01

428

’Process’ and Educational Analysis  

Microsoft Academic Search

The intention of this paper is to investigate the use of the term ‘process’ in educational analysis. Drawing on a model proposed by Apple & Weis (1985) for conceptualising ideological reproduction in education, the paper argues that ‘process’ is in greater need of clarification than the terms to which it refers. The claim is that ‘process’ has become a taken?for?granted

Richard Smith

1987-01-01

429

Effect of Dietary Supplementation of Galactomannan oligosaccharides and Chitosan on Performance and Serum Immune Parameters of 28-day Weaned Piglets Challenged with Pathogenic E.coli  

Microsoft Academic Search

Sun, Z.H., Tang, Z.R., Yin, Y.L., Huang, R.L., Li, T.J., Tang, S.X. and Tan, Z.L. 2009. Effect of dietary supplementation of galacto-mannan-oligosaccharides and chitosan on performance and serum immune parameters of 28-day weaned piglets challenged with pathogenic E. coli. J. Appl. Anim. Res., 36: 207–211.To determine the effects of galacto-mannan-oligosaccharides (GMOS) and chitosan (COS) on growth performance and serum immune

Z. H. Sun; Z. R. Tang; Y. L. Yin; R. L. Huang; T. J. Li; S. X. Tang; Z. L. Tan

2009-01-01

430

Hybrid protocol of remote implementations of quantum operations  

SciTech Connect

We propose a protocol of remote implementations of quantum operations by hybridizing bidirectional quantum-state teleportation (BQST) [Huelga et al., Phys. Rev. A 63, 042303 (2001)] and the Wang protocol [Wang, Phys. Rev. A 74, 032317 (2006)]. The protocol is available for remote implementations of quantum operations in the restricted sets specified in the paper. We also give a proof of the protocol and point out its optimization. As an extension, this hybrid protocol can be reduced to the BQST and Wang protocols.

Zhao Ningbo; Wang Anmin [Quantum Theory Group, Department of Modern Physics, University of Science and Technology of China, Hefei 230026 (China)

2007-12-15

431

In vitro anti-microbial and in vivo cytokine modulating effects of different prepared Chinese herbal medicines.  

PubMed

The toxicity, antimicrobial and cytokine modulating effects of herbal medicines in treating periodontal diseases were evaluated in this study. Using the broth dilution method and disc agar diffusion test, in individual and combined decocted preparations, different concentrations of Ching-Wei-San and its individual herbal components, Coptidis rhizoma, Angelicae sinensis radix, Rehmanniae radixet rhizom, Moutan radicis cortex, and Cimicifuga foetida, were tested for in vitro inhibitory effects on three well-known plaque-causing bacteria, Porphyromonas gingivialis, Streptococcus sanguis, and Streptococcus mutans, and two common pathogens, Staphylococcus aureus and Escherichia coli. The cytokine modulating effects were evaluated in Balb/c mice. The results suggested that one milliliter Ching-Wei-San at the 25,000 mg/mL concentration daily for the mice had significantly high levels in the liver function indexes in the 3-day acute toxicity test and in both the liver and kidney function indexes in the 28-day subacute toxicity test (P<0.01). The 250 mg/mL Ching-Wei-San is comparable to 250 mg/mL of tetracycline, and had similar inhibitory effects on the tested bacteria. Coptidis rhizoma (62.5 mg/mL) was the only individual herbal component to show 100% inhibitory effects. The mean cytokine ratios of IL-2, IL-4, IFN-gamma, and TNF-alpha in Balb/c mice treated with individual herbal components were shown to be different from each other. Ching-Wei-San modulated the immunity of mice, up-regulated IL-2, IL-4 and TNF-alpha, but down-regulated IFN-gamma. The effects of none of the individual herbal components alone can substitute for the cumulative effect of Ching-Wei-San. PMID:16962225

Lin, Shyh-Jye; Chen, Chung-Shih; Lin, Shih-Shen; Chou, Ming-Yung; Shih, Hung-Che; Lee, I-Pang; Kao, Chia-Tze; Ho, Chuan-Chen; Chen, Fong-Lin; Ho, Yung-Chyuan; Hsieh, Kuang-Hui; Huang, Chi-Ruei; Yang, Chi-Chiang

2006-08-07

432

Individual Papers from Proceedings of the 14th biennial southern ...  

Treesearch

Jan 12, 2010 ... Eisenbies, Mark H.; Burger, James A.; Aust, W. Michael; Patterson, Stephen C. ... Knapp, Benjamin O.; Wang, G. Geoff; Walker, Joan L. ... Nelson, John L.; Groninger, John W.; Battaglia, Loretta L.; Ruffner, Charles M.

433

Teleconference Summary - Provenge, December 14, 2006  

Center for Biologics Evaluation and Research (CBER)

Text Version... PRODUCT: Sipuleucel-T TO: File STN 125197/0 FROM: Gang Wang, Ph.D., CBER/OCBQ/DMPQ/MRB II, HFM-675 PARTICIPANTS ... More results from www.fda.gov/downloads/biologicsbloodvaccines/cellulargenetherapyproducts

434

Dendreon PLI - Preliminary Report - Provenge, February 25 ...  

Center for Biologics Evaluation and Research (CBER)

... ReportFrom: Finn, Thomas Sent: Thursday, February 25, 2010 10:41 AM To: 'Smith, Liz' Cc: Oh, Steven; Tull, Lori; Wang, Gang; Melhem, Randa ... More results from www.fda.gov/biologicsbloodvaccines/cellulargenetherapyproducts/approvedproducts

435

Telecon Summary, Information Request - Cervarix, August 29 ...  

Center for Biologics Evaluation and Research (CBER)

... SUMMARY DATE: August 29, 2007 TIME: 2:00 PM SPONSOR: GSK Bio PRODUCT: Cervarix TO: File STN 125259/0 FROM: Gang Wang, Ph.D ... More results from www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts

436

On the Existence of Sign Changing Solutions for Semilinear Dirichlet Problems  

Microsoft Academic Search

this paper we shall refine Wang's result andobtain more information on u 1 and on other solutions whose existence is proved via Morsetheory. Let us illustrate this with the following two theorems. More general results willbe stated and proved later.

Thomas Bartsch; Zhi-qiang Wang

1996-01-01

437

Comment by R. M. W. Musson on ``Comparison Between Probabilistic Seismic Hazard Analysis and Flood Frequency Analysis''  

NASA Astrophysics Data System (ADS)

It must be a rare occurrence to see, in the same scientific newspaper in the space of a little over a year, the same errors repeated by the same authors in two different articles, despite the fact that those errors had been refuted in that newspaper in the interim. I pointed out [Musson, 2004] the fallacies in a paper by Wang et al. ]2003[. These errors are now repeated by Wang and Ormsbee [2005], who refer back to Wang et al. [2003] but not to Musson [2004]. This raises questions about scientific method: We expect that science proceeds in some sort of forward direction and that errors are not repeated when identified. To see such a repetition as this raises at least the question of how Wang and Ormsbee [2005] were reviewed.

Musson, R. M. W.

2005-09-01

438

78 FR 19718 - Modifications To Labeling of Nicotine Replacement Therapy Products for Over-the-Counter Human Use  

Federal Register 2010, 2011, 2012, 2013

...31. Wang, D., et al., '' `Cut Down to Quit' With Nicotine Replacement Therapies in Smoking Cessation: A Systematic Review of Effectiveness and Economic Analysis,'' Health Technology Assessment, 12(2):iii-iv, ix-xi,...

2013-04-02

439

Curriculum Vitae: Jersey Chen  

Center for Biologics Evaluation and Research (CBER)

Text Version... JE, Chen J, Vaccarino V, Radford MJ, Ellerbeck EF, Wang Y. Thrombolytic therapy for eligible elderly patients with acute myocardial infarction. ... More results from www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials

440

Cholinergic augmentation with donepezil enhances recovery in short-term memory and sustained attention after traumatic brain injury 1,2 1 No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit on the author(s) or on any organization with which the author(s) is\\/are associated. 2 Reprints are not available from the author  

Microsoft Academic Search

Zhang L, Plotkin RC, Wang G, Sandel ME, Lee S. Cholinergic augmentation with donepezil enhances recovery in short-term memory and sustained attention after traumatic brain injury. Arch Phys Med Rehabil 2004;85:1050-5.

Lei Zhang; Rosette C Plotkin; Gary Wang; M. Elizabeth Sandel; Shuko Lee

2004-01-01

441

A Preliminary Study to Examine the Effects of Aerobic and Therapeutic (Nonaerobic) Exercise on Cardiorespiratory Fitness and Coronary Risk Reduction in Stroke Survivors  

Microsoft Academic Search

Rimmer JH, Rauworth AE, Wang EC, Nicola TL, Hill B. A preliminary study to examine the effects of aerobic and therapeutic (nonaerobic) exercise on cardiorespiratory fitness and coronary risk reduction in stroke survivors.

James H. Rimmer; Amy E. Rauworth; Edward C. Wang; Terry L. Nicola; Bernadette Hill

2009-01-01

442

JAY BROOKS JACKSON CURRICULUM VITAE  

Center for Biologics Evaluation and Research (CBER)

Text Version... Coombs RW, Welles SL, Hooper C, Reichelderfer PS, D ... Towler WI, James MM, Ray SC, Wang L ... Kamwendo D, Chipungu C, Maharaj R, Mushanyu J ... More results from www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials

443

Lattice dynamics of fct indium and hcp magnesium  

SciTech Connect

Phonon spectra of fct indium and hcp magnesium are calculated using the dynamic pseudopotential theory developed by Wang and Overhauser. Good agreement with experimental data is achieved with two adjustable pseudopotential parameters.

Chen, X.M.; Xuan, Y.; Overhauser, A.W. (Department of Physics, Purdue University, West Lafayette, Indiana 47907 (US))

1991-01-15

444

Scale Disparity and Spectral Transfer in Anisotropic Numerical Turbulence.  

National Technical Information Service (NTIS)

To study the effect of cancellations within long-range interactions on local isotropy at the small scales, we calculate explicitly the degree of cancellation in distant interactions in the simulations of Yeung & Brasseur and Yeung, Brasseur & Wang using t...

Y. Zhou P. K. Yeung J. G. Brasseur

1994-01-01

445

Mid-Cycle Review Meeting Minutes, June 10, 2011 ...  

Center for Biologics Evaluation and Research (CBER)

... DMPQ – M. Heidaran & G. Wang Requested teleconference with sponsor to discuss outstanding issues (483 citation update ; quality and batch ... More results from www.fda.gov/biologicsbloodvaccines/cellulargenetherapyproducts/approvedproducts

446

Correlative Studies of Solar Flares. Report for September 14, 1992 to September 14, 1996.  

National Technical Information Service (NTIS)

In October 1992, post-doc Haimin Wang was awarded a Compton GRO Fellowship by NASA to study the flares observed simultaneously by BATSE (Burst and Transient Experiment), OVRO (Owens Valley Radio Observatory), Yohkoh, and BBSO (Big Bear Solar Observatory)....

H. Zirin

1997-01-01

447

Word Processor Training on Intelligent Videodisc.  

ERIC Educational Resources Information Center

Presents an overview of the Wang Word Processing Intelligent Learning Program on interactive videodisc, which is used at Eastman Kodak to train hundreds of word processing operators. Operation of the program is discussed in detail. (MBR)

Yampolsky, Michael

1983-01-01

448

Treesearch - Forest Service Research & Development  

Treesearch

2006, Long-term changes in forest structure and species composition of an upland oak ... Borkh., American chestnut, Fagaceae (Beech Family), Wang, G. Geoff; Knapp, .... 1954, A potential timber-type Chinese chestnut, Diller, Jesse D. NRS.

449

CDER Small Business Assistance: Clinical Trials Forum, April ...  

Center for Drug Evaluation (CDER)

... Agenda (PDF - 30KB). ... "Clinical Trial Design" - Sue-Jane Wang Ph.D, Office of Biostatistics, Office of Translational Science, CDER (PDF - 541KB); ... More results from www.fda.gov/drugs/newsevents

450

Efficiency and security problems of anonymous key agreement protocol based on chaotic maps  

NASA Astrophysics Data System (ADS)

In 2011, Niu-Wang proposed an anonymous key agreement protocol based on chaotic maps in [Niu Y, Wang X. An anonymous key agreement protocol based on chaotic maps. Commun Nonlinear Sci Simulat 2011;16(4):1986-92]. Niu-Wang's protocol not only achieves session key agreement between a server and a user, but also allows the user to anonymously interact with the server. Nevertheless, this paper points out that Niu-Wang's protocol has the following efficiency and security problems: (1) The protocol has computational efficiency problem when a trusted third party decrypts the user sending message. (2) The protocol is vulnerable to Denial of Service (DoS) attack based on illegal message modification by an attacker.

Yoon, Eun-Jun

2012-07-01

451

Kick Off Meeting Minutes  

Center for Biologics Evaluation and Research (CBER)

Text Version... Joydeep Ghosh Terrolyn Thomas Email sent to sponsor to request information. DMPQ cannot find FEI # ... Gang Wang Terrolyn Thomas ... More results from www.fda.gov/downloads/biologicsbloodvaccines/cellulargenetherapyproducts

452

A critical review of the diagnosis and management of Barrett’s esophagus: the AGA Chicago Workshop 1 1 Members of the workshop composed a group of international experts in BE from gastroenterology, surgery, pathology, molecular biology, outcomes, and epidemiology. Conference chairman: Prateek Sharma; conference moderator: Kenneth McQuaid; group leaders: John Dent, M. Brian Fennerty, Richard Sampliner, Stuart Spechler; participants: Alan Cameron, Douglas Corley, Gary Falk, John Goldblum, John Hunter, Janusz Jankowski, Lars Lundell, Brian Reid, Nicholas Shaheen, Amnon Sonnenberg, Kenneth Wang, and Wilfred Weinstein  

Microsoft Academic Search

Background & Aims: The diagnosis and management of Barrett’s esophagus (BE) are controversial. We conducted a critical review of the literature in BE to provide guidance on clinically relevant issues. Methods: A multidisciplinary group of 18 participants evaluated the strength and the grade of evidence for 42 statements pertaining to the diagnosis, screening, surveillance, and treatment of BE. Each member

Prateek Sharma; Kenneth McQuaid; John Dent; M. Brian Fennerty; Richard Sampliner; Stuart Spechler; Alan Cameron; Douglas Corley; Gary Falk; John Goldblum; John Hunter; Janusz Jankowski; Lars Lundell; Brian Reid; Nicholas J. Shaheen; Amnon Sonnenberg; Kenneth Wang; Wilfred Weinstein

2004-01-01

454

Quality of Life of Individuals with Intellectual Disabilities and Their Families in China: Research and Applications  

Microsoft Academic Search

\\u000a The concept of quality of life (QOL) and its extension, family quality of life (FQoL) are increasingly being studied in the\\u000a field of intellectual disabilities in China as an important framework for assessing family’s need of support and service,\\u000a guiding organization and service delivery system changes and evaluating quality family outcomes (Xu, Wang, & Hu, 2005; Xu,\\u000a Wang, & Xiang,

Mian Wang

455

Assessing the Extent to which Career Development Impacts Employee Commitment: a Case Study of the ICT industry in Hong Kong  

Microsoft Academic Search

Many employee commitment studies have been undertaken recently in Mainland China that suggested necessary modifications should be made to the western traditional three-component commitment model to suit the Chinese context. This paper attempts to validate the generalizability of Wang’s five-component commitment model as well as its relationship with career development among 300 ICT professionals in Hong Kong. Results suggest that

Joseph Chui; Canon Tong; Joseph M Mula

2007-01-01

456

2006 Bibliography — CBIIT: Welcome to the NCI Center for Biomedical Informatics and Information Technology  

Cancer.gov

Bakay M, Wang Z, Melcon G, Schiltz L, Xuan J, Zhao P, Sartorelli V, Seo J, Pegoraro E, Angelini C, Shneiderman B, Escolar D, Chen YW, Winokur ST, Pachman LM, Fan C, Mandler R, Nevo Y, Gordon E, Zhu Y, Dong Y, Wang Y, Hoffman EP. Nuclear envelope dystrophies show a transcriptional fingerprint suggesting disruption of Rb-MyoD pathways in muscle regeneration. Brain.

457

Design of Density Functionals That Are Broadly Accurate for Thermochemistry, Thermochemical Kinetics, and Nonbonded Interactions  

Microsoft Academic Search

This paper develops two new hybrid meta exchange-correlation functionals for thermochemistry, thermochemical kinetics, and nonbonded interactions. The new functionals are called PW6B95 (6-parameter functional based on Perdew-Wang-91 exchange and Becke-95 correlation) and PWB6K (6-parameter functional for kinetics based on Perdew-Wang-91 exchange and Becke-95 correlation). The resulting methods were comparatively assessed against the MGAE109\\/3 main group atomization energy database, against the

Yan Zhao; Donald G. Truhlar

2005-01-01

458

Protection against Radiation-Induced Bone Marrow and Intestinal Injuries by Cordyceps sinensis, a Chinese Herbal Medicine  

Microsoft Academic Search

Liu, W-C., Wang, S-C., Tsai, M-L., Chen, M-C., Wang, Y-C., Hong, J-H., McBride, W. H. and Chiang, C-S. Protec- tion against Radiation-Induced Bone Marrow and Intestinal Injuries by Cordyceps sinensis, a Chinese Herbal Medicine. Radiat. Res. 166, 900-907 (2006). Bone marrow and intestinal damage limits the efficacy of radiotherapy for cancer and can result in death if the whole body

Wei-Chung Liu; Shu-Chi Wang; Min-Lung Tsai; Meng-Chi Chen; Ya-Chen Wang; Ji-Hong Hong; William H. McBride; Chi-Shiun Chiang

2006-01-01

459

Green’s functions and boundary element method formulation for 3D anisotropic media  

Microsoft Academic Search

The implementation of Wang’s theoretical solution is presented for elastostatic displacement Green’s function for three-dimensional solids of general anisotropy. Excerpts from the authors’ fortran code are included. A numerical algorithm for the calculation of the derivatives of the Green’s displacements and stresses is also introduced. These implementations have been incorporated into a boundary element method (BEM) code developed by the

Fulvio Tonon; Ernian Pan; Bernard Amadei

2001-01-01

460

Tibetan land use and change near khawa karpo, Eastern Himalayas  

Microsoft Academic Search

Collaborating Authors: Bee Gunn, Wayne Law, George Yatskievych, Wu Sugong, Fang Zhendong, Ma Jian, Wang Yuhua, Andrew Willson,\\u000a Peng Shengjing, Zhang Chuanling, Sun Hongyan, Meng Zhengui, Liu Lin, Senam Dorji, Ana, Liqing Wangcuo, Sila Cili, Adu, Naji,\\u000a Amu, Sila Cimu, Sila Lamu, Lurong Pingding, Zhima Yongzong, Loangbao, Bianma Cimu, Gerong Cili, Wang Kai, Sila Pingchu, Axima,\\u000a and Benjamin Staver.TIBETAN LAND

Jan Salick; Yang Yongping; Anthony Amend

2005-01-01

461

Robust Pose Recognition of the Obscured Human Body  

Microsoft Academic Search

This paper presents a robust automated noninvasive video monitoring approach to recover the human pose in conditions with\\u000a persistent heavy obscuration. The proposed methods are compared with Ramanan’s stylized pose detection method and Wang’s sequential\\u000a pose model. The experimental results show that the proposed method performs significantly better than Ramanan’s approach,\\u000a is able to estimate the obscured body pose with

Ching-Wei Wang; Andrew Hunter

2010-01-01

462

Comparison of visual and auditory evoked cortical potentials in migraine patients between attacks  

Microsoft Academic Search

Objective: As both habituation of pattern reversal visual evoked potentials (PR-VEP) (Schoenen J, Wang W, Albert A, Delwaide PJ. Potentiation instead of habituation characterizes visual evoked potentials in migraine patients between attacks. Eur J Neurol 1995;2:115–122) and intensity dependence of auditory evoked cortical potentials (IDAP) (Wang W, Timsit-Berthier M, Schoenen J. Intensity dependence of auditory evoked potentials in migraine: an

J. Áfra; A. Proietti Cecchini; P. S. Sándor; J. Schoenen

2000-01-01

463

Remote sensing assessment of sediment re-suspension during Hurricane Frances in Apalachicola Bay, USA  

Microsoft Academic Search

Assessments of hurricane-induced environmental impacts are important to coastal management and risk analysis of ecosystems. In this study, a previously-developed remote sensing model for non-hurricane conditions by Wang et al. [Wang, H. Q., Hladik, C. M., Milla, K., Huang, W. R., Edmiston, L., Harwell, M. A., & Schalles, J. F. (in press). Detecting and mapping water quality indicators in Apalachicola

Shuisen Chen; Wenrui Huang; Hongqing Wang; Dan Li

2009-01-01

464

Correction of atmospheric effect on ADEOS\\/OCTS ocean color data: Algorithm description and evaluation of its performance  

Microsoft Academic Search

This paper first describes the atmospheric correction algorithm for OCTS visible band data used at NASDA\\/EOC. Sharing a basic\\u000a structure with Gordon and Wang’s Sea WiFS algorithm, it uses 10 candidate aerosol models including the “Asian dust model”\\u000a introduced in consideration of the unique feature of aerosols over the east Asian waters. Based on the observations at 670\\u000a and 865

Hajime Fukushima; Akiko Higurashi; Yasushi Mitomi; Teruyuki Nakajima; Toshimitsu Noguchi; Toshio Tanaka; Mitsuhiro Toratani

1998-01-01

465

Carving out Their Own Niche  

ERIC Educational Resources Information Center

|Asian-American performers were few and far between when Dr. Oliver Wang was growing up in the 1970s and '80s. Looking back, Dr. Wang, an assistant professor in sociology at California State University-Long Beach, says the lack of artists may have been the result of a lack of role models, since Asian immigrants did not begin to arrive in the…

Lum, Lydia

2007-01-01

466

Analysis of similarity\\/dissimilarity of DNA sequences based on a 3-D graphical representation  

Microsoft Academic Search

Based on a 3-D graphical representation of DNA primary sequences by Li and Wang [C. Li, J. Wang, Comb. Chem. High Throughput Screen. 7 (2004) 23], we outline one approach to arrive at quantification of similarities by constructing a three-component vector whose components are the geometrical center and a four-component vector consisting of the graph radius associated with DNA curves.

Yu-Hua Yao; Xu-Ying Nan; Tian-Ming Wang

2005-01-01

467

Race--Social, Biological, or Lemonade?  

ERIC Educational Resources Information Center

|This paper presents comments on an article by R. L. Sternberg, E. L. Grigorenko, and K. K. Kidd and another article by H. Tang, T. Quertermous, B. Rodriguez, S. L. Kardia, X. Zhu, X., A. Brown, et al. (2005). On the day that the author of this paper reads Sternberg, Grigorenko, and Kidd's (January 2005) article on race, an article from the…

Carey, Gregory

2006-01-01

468

Preliminary analysis on boundary climate effects between oasis and desert in the north margin of the Taklimakan Desert  

Microsoft Academic Search

According to the analysis to the climatic data of Xiao Tang in desert, Lun Tai in oasis during 1992 to 1997, the following viewpoints were noted: (1)The air temperature of desert is lower than the one of oasis in winter, the air temperature rise gradually from oasis to desert in summer. The diurnal range and annual range of air temperature

Qing He; Hongjun Li; Xinjian Li; Qing Yang; Xiaoling Pan; Wei Gao

2004-01-01

469

THE PREDICTION OF NOx FORMATION FOR THE COMBUSTION OF NITROGEN-DOPED DROPLETS OF HEXANE INSIDE A REFRACTORY TUBE  

Microsoft Academic Search

The detailed kinetic model developed by Tang and Churchill for the prediction of the combustion of premixed-gaseous or evaporated-liquid hydrocarbon fuels in a refractory plug flow burner has been extended to account for nitrogen compounds in the fuel. In the modified model the nitrogen compounds are postulated to decompose thermally to HCN in the flame front prior to oxidation. The

Shu-Kin Tang; Stuart W. Churchill

1981-01-01

470

The Year of the Pond  

ERIC Educational Resources Information Center

|Water gardens became popular in China during the Tang Dynasty and goldfish were domesticated more than 1000 years ago. Beyond being beautiful and tranquil, water gardens have the potential for much learning in an educational setting, especially for learning through art. In this article, the author shares how he collaborated with another teacher…

Hinshaw, Craig

2010-01-01

471

46 CFR 160.043-6 - Marking and packing.  

Code of Federal Regulations, 2011 CFR

...General. Jackknives specified by this subpart shall be stamped or otherwise permanently and legibly marked on the tang of the blade with the manufacturer's name or with a trade mark of such known character that the source of manufacture may be readily...

2011-10-01

472

46 CFR 160.043-6 - Marking and packing.  

Code of Federal Regulations, 2012 CFR

...General. Jackknives specified by this subpart shall be stamped or otherwise permanently and legibly marked on the tang of the blade with the manufacturer's name or with a trade mark of such known character that the source of manufacture may be readily...

2012-10-01

473

Electronic and optical properties of ferromagnetic Ga1-xMnxAs in a multiband tight-binding approach  

NASA Astrophysics Data System (ADS)

We consider the electronic properties of ferromagnetic bulk Ga1-xMnxAs at zero temperature using two realistic tight-binding models, one due to Tang and Flatté and one due to Mašek. In particular, we study the density of states, the Fermi energy, the inverse participation ratio, and the optical conductivity with varying impurity concentration x=0.01-0.15 . The results are very sensitive to the assumptions made for the on-site and hopping matrix elements of the Mn impurities. For low concentrations, x<0.02 , Mašek’s model shows only small deviations from the case of p -doped GaAs with increased number of holes while within Tang and Flatté’s model an impurity-band forms. For higher concentrations x , Mašek’s model shows minor quantitative changes in the properties we studied while the results of the Tang and Flatté model exhibit qualitative changes including strong localization of eigenstates with energies close to the band edge. These differences between the two approaches are in particular visible in the optical conductivity, where Mašek’s model shows a Drude peak at zero frequency while no such peak is observed in Tang and Flatté’s model. Interestingly, although the two models differ qualitatively the calculated effective optical masses of both models are similar within the range of 0.4-1.0 of the free-electron mass.

Turek, Marko; Siewert, Jens; Fabian, Jaroslav

2008-08-01

474

Rapid screening of radioactivity in food for emergency response  

Microsoft Academic Search

This paper describes the development of methods for the rapid screening of gross alpha (GA) and gross beta (GB) radioactivity in liquid foods, specifically, Tang drink mix, apple juice, and milk, as well as screening of GA, GB, and gamma radioactivity from surface deposition on apples. Detailed procedures were developed for spiking of matrices with 241Am (alpha radioactivity), 90Sr\\/90Y (beta

A. Bari; A. J. Khan; T. M. Semkow; U.-F. Syed; A. Roselan; D. K. Haines; G. Roth; M. Arndt

2011-01-01