Sample records for target physics issues

  1. The physics basis for ignition using indirect-drive targets on the National Ignition Facility

    NASA Astrophysics Data System (ADS)

    Lindl, John D.; Amendt, Peter; Berger, Richard L.; Glendinning, S. Gail; Glenzer, Siegfried H.; Haan, Steven W.; Kauffman, Robert L.; Landen, Otto L.; Suter, Laurence J.

    2004-02-01

    The 1990 National Academy of Science final report of its review of the Inertial Confinement Fusion Program recommended completion of a series of target physics objectives on the 10-beam Nova laser at the Lawrence Livermore National Laboratory as the highest-priority prerequisite for proceeding with construction of an ignition-scale laser facility, now called the National Ignition Facility (NIF). These objectives were chosen to demonstrate that there was sufficient understanding of the physics of ignition targets that the laser requirements for laboratory ignition could be accurately specified. This research on Nova, as well as additional research on the Omega laser at the University of Rochester, is the subject of this review. The objectives of the U.S. indirect-drive target physics program have been to experimentally demonstrate and predictively model hohlraum characteristics, as well as capsule performance in targets that have been scaled in key physics variables from NIF targets. To address the hohlraum and hydrodynamic constraints on indirect-drive ignition, the target physics program was divided into the Hohlraum and Laser-Plasma Physics (HLP) program and the Hydrodynamically Equivalent Physics (HEP) program. The HLP program addresses laser-plasma coupling, x-ray generation and transport, and the development of energy-efficient hohlraums that provide the appropriate spectral, temporal, and spatial x-ray drive. The HEP experiments address the issues of hydrodynamic instability and mix, as well as the effects of flux asymmetry on capsules that are scaled as closely as possible to ignition capsules (hydrodynamic equivalence). The HEP program also addresses other capsule physics issues associated with ignition, such as energy gain and energy loss to the fuel during implosion in the absence of alpha-particle deposition. The results from the Nova and Omega experiments approach the NIF requirements for most of the important ignition capsule parameters, including

  2. Polarized targets in high energy physics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cates, G.D. Jr.

    1994-12-01

    Various approaches are discussed for producing polarized nuclear targets for high energy physics experiments. As a unifying theme, examples are drawn from experiments to measure spin dependent structure functions of nucleons in deep inelastic scattering. This single physics goal has, over roughly two decades, been a driving force in advances in target technology. Actual or planned approaches have included solid targets polarized by dynamic nuclear polarization (DNP), several types of internal targets for use in storage rings, and gaseous {sup 3}He targets polarized by spin-exchange optical pumping. This last approach is the type of target adopted for SLAC E-142, anmore » experiment to measure the spin structure function of the neutron, and is described in detail.« less

  3. Measurement of physical activity, exercise, and physical fitness in children: issues and concerns.

    PubMed

    Rice, M H; Howell, C C

    2000-06-01

    Data to support the type and level of physical activity that are necessary for health benefits in children and for later prevention of disease as adults are not available. This lack of information may be caused by inconsistency in terminology and by issues and concerns with available instruments to measure the concept. The purpose of this article is to address measurement issues related to physical activity/exercise or physical fitness in children. Implications of these issues for researchers and practitioners are discussed.

  4. A course treating ethical issues in physics.

    PubMed

    Thomsen, Marshall

    2007-03-01

    A course focusing on ethical issues in physics has been taught to undergraduate students at Eastern Michigan University since 1988. The course covers both responsible conduct of research and ethical issues associated with how physicists interact with the rest of society. Since most undergraduate physics majors will not have a career in academia, it is important that a course such as this address issues that will be relevant to physicists in a wide range of job situations. There is a wealth of published work that can be drawn on for reading assignments.

  5. Special issue on cluster algebras in mathematical physics

    NASA Astrophysics Data System (ADS)

    Di Francesco, Philippe; Gekhtman, Michael; Kuniba, Atsuo; Yamazaki, Masahito

    2014-02-01

    This is a call for contributions to a special issue of Journal of Physics A: Mathematical and Theoretical dedicated to cluster algebras in mathematical physics. Over the ten years since their introduction by Fomin and Zelevinsky, the theory of cluster algebras has witnessed a spectacular growth, first and foremost due to the many links that have been discovered with a wide range of subjects in mathematics and, increasingly, theoretical and mathematical physics. The main motivation of this special issue is to gather together reviews, recent developments and open problems, mainly from a mathematical physics viewpoint, into a single comprehensive issue. We expect that such a special issue will become a valuable reference for the broad scientific community working in mathematical and theoretical physics. The issue will consist of invited review articles and contributed papers containing new results on the interplays of cluster algebras with mathematical physics. Editorial policy The Guest Editors for this issue are Philippe Di Francesco, Michael Gekhtman, Atsuo Kuniba and Masahito Yamazaki. The areas and topics for this issue include, but are not limited to: discrete integrable systems arising from cluster mutations cluster structure on Poisson varieties cluster algebras and soliton interactions cluster positivity conjecture Y-systems in the thermodynamic Bethe ansatz and Zamolodchikov's periodicity conjecture T-system of transfer matrices of integrable lattice models dilogarithm identities in conformal field theory wall crossing in 4d N = 2 supersymmetric gauge theories 4d N = 1 quiver gauge theories described by networks scattering amplitudes of 4d N = 4 theories 3d N = 2 gauge theories described by flat connections on 3-manifolds integrability of dimer/Ising models on graphs. All contributions will be refereed and processed according to the usual procedure of the journal. Guidelines for preparation of contributions The deadline for contributed papers is 31 March

  6. Special issue on cluster algebras in mathematical physics

    NASA Astrophysics Data System (ADS)

    Di Francesco, Philippe; Gekhtman, Michael; Kuniba, Atsuo; Yamazaki, Masahito

    2013-12-01

    This is a call for contributions to a special issue of Journal of Physics A: Mathematical and Theoretical dedicated to cluster algebras in mathematical physics. Over the ten years since their introduction by Fomin and Zelevinsky, the theory of cluster algebras has witnessed a spectacular growth, first and foremost due to the many links that have been discovered with a wide range of subjects in mathematics and, increasingly, theoretical and mathematical physics. The main motivation of this special issue is to gather together reviews, recent developments and open problems, mainly from a mathematical physics viewpoint, into a single comprehensive issue. We expect that such a special issue will become a valuable reference for the broad scientific community working in mathematical and theoretical physics. The issue will consist of invited review articles and contributed papers containing new results on the interplays of cluster algebras with mathematical physics. Editorial policy The Guest Editors for this issue are Philippe Di Francesco, Michael Gekhtman, Atsuo Kuniba and Masahito Yamazaki. The areas and topics for this issue include, but are not limited to: discrete integrable systems arising from cluster mutations cluster structure on Poisson varieties cluster algebras and soliton interactions cluster positivity conjecture Y-systems in the thermodynamic Bethe ansatz and Zamolodchikov's periodicity conjecture T-system of transfer matrices of integrable lattice models dilogarithm identities in conformal field theory wall crossing in 4d N = 2 supersymmetric gauge theories 4d N = 1 quiver gauge theories described by networks scattering amplitudes of 4d N = 4 theories 3d N = 2 gauge theories described by flat connections on 3-manifolds integrability of dimer/Ising models on graphs. All contributions will be refereed and processed according to the usual procedure of the journal. Guidelines for preparation of contributions The deadline for contributed papers is 31 March

  7. Special issue on cluster algebras in mathematical physics

    NASA Astrophysics Data System (ADS)

    Di Francesco, Philippe; Gekhtman, Michael; Kuniba, Atsuo; Yamazaki, Masahito

    2013-11-01

    This is a call for contributions to a special issue of Journal of Physics A: Mathematical and Theoretical dedicated to cluster algebras in mathematical physics. Over the ten years since their introduction by Fomin and Zelevinsky, the theory of cluster algebras has witnessed a spectacular growth, first and foremost due to the many links that have been discovered with a wide range of subjects in mathematics and, increasingly, theoretical and mathematical physics. The main motivation of this special issue is to gather together reviews, recent developments and open problems, mainly from a mathematical physics viewpoint, into a single comprehensive issue. We expect that such a special issue will become a valuable reference for the broad scientific community working in mathematical and theoretical physics. The issue will consist of invited review articles and contributed papers containing new results on the interplays of cluster algebras with mathematical physics. Editorial policy The Guest Editors for this issue are Philippe Di Francesco, Michael Gekhtman, Atsuo Kuniba and Masahito Yamazaki. The areas and topics for this issue include, but are not limited to: discrete integrable systems arising from cluster mutations cluster structure on Poisson varieties cluster algebras and soliton interactions cluster positivity conjecture Y-systems in the thermodynamic Bethe ansatz and Zamolodchikov's periodicity conjecture T-system of transfer matrices of integrable lattice models dilogarithm identities in conformal field theory wall crossing in 4d N = 2 supersymmetric gauge theories 4d N = 1 quiver gauge theories described by networks scattering amplitudes of 4d N = 4 theories 3d N = 2 gauge theories described by flat connections on 3-manifolds integrability of dimer/Ising models on graphs. All contributions will be refereed and processed according to the usual procedure of the journal. Guidelines for preparation of contributions The deadline for contributed papers is 31 March

  8. Special issue on cluster algebras in mathematical physics

    NASA Astrophysics Data System (ADS)

    Di Francesco, Philippe; Gekhtman, Michael; Kuniba, Atsuo; Yamazaki, Masahito

    2013-10-01

    This is a call for contributions to a special issue of Journal of Physics A: Mathematical and Theoretical dedicated to cluster algebras in mathematical physics. Over the ten years since their introduction by Fomin and Zelevinsky, the theory of cluster algebras has witnessed a spectacular growth, first and foremost due to the many links that have been discovered with a wide range of subjects in mathematics and, increasingly, theoretical and mathematical physics. The main motivation of this special issue is to gather together reviews, recent developments and open problems, mainly from a mathematical physics viewpoint, into a single comprehensive issue. We expect that such a special issue will become a valuable reference for the broad scientific community working in mathematical and theoretical physics. The issue will consist of invited review articles and contributed papers containing new results on the interplays of cluster algebras with mathematical physics. Editorial policy The Guest Editors for this issue are Philippe Di Francesco, Michael Gekhtman, Atsuo Kuniba and Masahito Yamazaki. The areas and topics for this issue include, but are not limited to: discrete integrable systems arising from cluster mutations cluster structure on Poisson varieties cluster algebras and soliton interactions cluster positivity conjecture Y-systems in the thermodynamic Bethe ansatz and Zamolodchikov's periodicity conjecture T-system of transfer matrices of integrable lattice models dilogarithm identities in conformal field theory wall crossing in 4d N = 2 supersymmetric gauge theories 4d N = 1 quiver gauge theories described by networks scattering amplitudes of 4d N = 4 theories 3d N = 2 gauge theories described by flat connections on 3-manifolds integrability of dimer/Ising models on graphs. All contributions will be refereed and processed according to the usual procedure of the journal. Guidelines for preparation of contributions The deadline for contributed papers is 31 March

  9. Special issue on quantum physics with non-Hermitian operators Special issue on quantum physics with non-Hermitian operators

    NASA Astrophysics Data System (ADS)

    Bender, Carl M.; Fring, Andreas; Guenther, Uwe; Jones, Hugh F.

    2012-01-01

    This is a call for contributions to a special issue of Journal of Physics A: Mathematical and Theoretical dedicated to quantum physics with non-Hermitian operators. The main motivation behind this special issue is to gather together recent results, developments and open problems in this rapidly evolving field of research in a single comprehensive volume. We expect that such a special issue will become a valuable reference for the broad scientific community working in mathematical and theoretical physics. The issue will be open to all contributions containing new results on non-Hermitian theories which are explicitly PT-symmetric and/or pseudo-Hermitian or quasi-Hermitian. The main novelties in the past years in this area have been many experimental observations, realizations, and applications of PT symmetric Hamiltonians in optics and microwave cavities. We especially invite contributions on the theoretical interpretations of these recent PT-symmetric experiments and on theoretical proposals for new experiments. Editorial policy The Guest Editors for this issue are Carl Bender, Andreas Fring, Uwe Guenther and Hugh Jones. The areas and topics for this issue include, but are not limited to: spectral problems novel properties of complex optical potentials PT-symmetry related threshold lasers and spectral singularities construction of metric operators scattering theory supersymmetric theories Lie algebraic and Krein-space methods random matrix models classical and semi-classical models exceptional points in model systems operator theoretic approaches microwave cavities aspects of integrability and exact solvability field theories with indefinite metric All contributions will be refereed and processed according to the usual procedure of the journal. Papers should report original and significant research that has not already been published. Guidelines for preparation of contributions The deadline for contributed papers will be 31 March 2012. This deadline will allow the

  10. Special issue on quantum physics with non-Hermitian operators Special issue on quantum physics with non-Hermitian operators

    NASA Astrophysics Data System (ADS)

    Bender, Carl M.; Fring, Andreas; Guenther, Uwe; Jones, Hugh F.

    2012-01-01

    This is a call for contributions to a special issue of Journal of Physics A: Mathematical and Theoretical dedicated to quantum physics with non-Hermitian operators. The main motivation behind this special issue is to gather together recent results, developments and open problems in this rapidly evolving field of research in a single comprehensive volume. We expect that such a special issue will become a valuable reference for the broad scientific community working in mathematical and theoretical physics. The issue will be open to all contributions containing new results on non-Hermitian theories which are explicitly PT-symmetric and/or pseudo-Hermitian or quasi-Hermitian. The main novelties in the past years in this area have been many experimental observations, realizations, and applications of PT symmetric Hamiltonians in optics and microwave cavities. We especially invite contributions on the theoretical interpretations of these recent PT-symmetric experiments and on theoretical proposals for new experiments. Editorial policy The Guest Editors for this issue are Carl Bender, Andreas Fring, Uwe Guenther and Hugh Jones. The areas and topics for this issue include, but are not limited to: spectral problems novel properties of complex optical potentials PT-symmetry related threshold lasers and spectral singularities construction of metric operators scattering theory supersymmetric theories Lie algebraic and Krein-space methods random matrix models classical and semi-classical models exceptional points in model systems operator theoretic approaches microwave cavities aspects of integrability and exact solvability field theories with indefinite metric All contributions will be refereed and processed according to the usual procedure of the journal. Papers should report original and significant research that has not already been published. Guidelines for preparation of contributions The deadline for contributed papers will be 31 March 2012. This deadline will allow the

  11. Addressing Physical and Emotional Issues in Children's Literature

    ERIC Educational Resources Information Center

    Johnson, Jonathon

    2010-01-01

    The purpose of this paper is to examine how physical and mental disabilities are addressed in children's literature. Many authors are able to integrate the issues into their work in a way that enhances the story and benefits the reader. As young readers learn about the issues and struggles faced by children with mental and physical disabilities,…

  12. Special issue on coherent states: mathematical and physical aspects Special issue on coherent states: mathematical and physical aspects

    NASA Astrophysics Data System (ADS)

    Twareque Ali, Syed; Antoine, Jean-Pierre; Bagarello, Fabio; Gazeau, Jean-Pierre

    2011-07-01

    This is a call for contributions to a special issue of Journal of Physics A: Mathematical and Theoretical dedicated to coherent states. The motivation behind this special issue is to gather in a single comprehensive volume the main aspects (past and present), latest developments, different viewpoints and directions being followed in this multidisciplinary field. Given the impressive development of the field in the past two decades, the topicality of such a volume can hardly be overemphasized. We strongly believe that such a special issue could become a particularly valuable reference for the broad scientific community working in mathematical and theoretical physics, as well as in signal processing and mathematics. Editorial policy The Guest Editors for this issue will be Syed Twareque Ali, Jean-Pierre Antoine, Fabio Bagarello and Jean-Pierre Gazeau. Potential topics include, but are not limited to, developments in the theory and applications of coherent states in: quantum optics, optomechanics, Bose-Einstein condensates quantum information, quantum measurement signal processing quantum gravity pseudo-Hermitian quantum mechanics supersymmetric quantum mechanics non-commutative quantum mechanics quantization theory harmonic and functional analysis operator theory Berezin-Toeplitz operators, PT-symmetric operators holomorphic representation theory, reproducing kernel spaces generalization of coherent states All contributions will be refereed and processed according to the usual procedure of the journal. Papers should report original and significant research that has not already been published. Guidelines for preparation of contributions The deadline for contributed papers will be 31 October 2011. This deadline will allow the special issue to appear before the end of May 2012 There is a nominal page limit of 15 printed pages per contribution (invited review papers can be longer). For papers exceeding this limit, the Guest Editors reserve the right to request a

  13. Special issue on coherent states: mathematical and physical aspects Special issue on coherent states: mathematical and physical aspects

    NASA Astrophysics Data System (ADS)

    Twareque Ali, Syed; Antoine, Jean-Pierre; Bagarello, Fabio; Gazeau, Jean-Pierre

    2011-06-01

    This is a call for contributions to a special issue of Journal of Physics A: Mathematical and Theoretical dedicated to coherent states. The motivation behind this special issue is to gather in a single comprehensive volume the main aspects (past and present), latest developments, different viewpoints and directions being followed in this multidisciplinary field. Given the impressive development of the field in the past two decades, the topicality of such a volume can hardly be overemphasized. We strongly believe that such a special issue could become a particularly valuable reference for the broad scientific community working in mathematical and theoretical physics, as well as in signal processing and mathematics. Editorial policy The Guest Editors for this issue will be Syed Twareque Ali, Jean-Pierre Antoine, Fabio Bagarello and Jean-Pierre Gazeau. Potential topics include, but are not limited to, developments in the theory and applications of coherent states in: quantum optics, optomechanics, Bose-Einstein condensates quantum information, quantum measurement signal processing quantum gravity pseudo-Hermitian quantum mechanics supersymmetric quantum mechanics non-commutative quantum mechanics quantization theory harmonic and functional analysis operator theory Berezin-Toeplitz operators, PT-symmetric operators holomorphic representation theory, reproducing kernel spaces generalization of coherent states All contributions will be refereed and processed according to the usual procedure of the journal. Papers should report original and significant research that has not already been published. Guidelines for preparation of contributions The deadline for contributed papers will be 31 October 2011. This deadline will allow the special issue to appear before the end of May 2012 There is a nominal page limit of 15 printed pages per contribution (invited review papers can be longer). For papers exceeding this limit, the Guest Editors reserve the right to request a

  14. Physical punishment, culture, and rights: current issues for professionals.

    PubMed

    Durrant, Joan E

    2008-02-01

    Once considered a legitimate parenting tool, physical punishment is increasingly being redefined as a developmental risk factor by health professionals. Three forces that have contributed to this significant social change are the evolution of pediatric psychology, increasing understanding of the dynamics of parental violence, and growing recognition of children as rights bearers. However, despite the consistency of research findings demonstrating the risks of physical punishment, some practitioners still struggle with the question of whether physical punishment is an appropriate practice among some cultural or ethnic groups. This issue is explored through an analysis of studies examining cultural differences and similarities in physical punishment's effects, as well as legal decisions made throughout the world. Despite practitioners' awareness of the prevalence and impact of parental violence, some still struggle with deciding where to "draw the line" in advising parents about spanking. This issue is addressed through an examination of the role that physical punishment plays in child maltreatment. Finally, the human rights perspective on physical punishment is offered as a new lens through which practitioners may view physical punishment to clarify the fuzzy issues of cultural relativity and the punishment-abuse dichotomy.

  15. Physics issues of gamma ray burst emissions

    NASA Technical Reports Server (NTRS)

    Liang, Edison

    1987-01-01

    The critical physics issues in the interpretation of gamma-ray-burst spectra are reviewed. An attempt is made to define the emission-region parameter space satisfying the maximum number of observational and theoretical constraints. Also discussed are the physical mechanisms responsible for the bursts that are most consistent with the above parameter space.

  16. Special Issue on "Neutrino Oscillations: Celebrating the Nobel Prize in Physics 2015" in Nuclear Physics B

    NASA Astrophysics Data System (ADS)

    Ohlsson, Tommy

    2016-07-01

    In 2015, the Nobel Prize in Physics was awarded jointly to Takaaki Kajita from the Super-Kamiokande Collaboration and Arthur B. McDonald from the SNO Collaboration ;for the discovery of neutrino oscillations, which shows that neutrinos have mass;. Furthermore, the Daya Bay, K2K and T2K, KamLAND, SNO, and Super-Kamiokande Collaborations shared the Fundamental Physics Breakthrough Prize the same year. In order to celebrate this successful and fruitful year for neutrino oscillations, the editors and the publisher of Nuclear Physics B decided to publish a Special Issue on neutrino oscillations. We invited prominent scientists in the area of neutrino physics that relates to neutrino oscillations to write contributions for this Special Issue, which was open to both original research articles as well as review articles. The authors of this Special Issue consist of e.g. the two Nobel Laureates, International Participants of the Nobel Symposium 129 on Neutrino Physics at Haga Slott in Enköping, Sweden (August 19-24, 2004), selected active researchers, and members from large experimental collaborations with major results in the last ten years. In total, this Special Issue consists of 28 contributions. Please note that the cover of this Special Issue contains a figure from each of the 26 contributions that have figures included.

  17. Optical simulation of flying targets using physically based renderer

    NASA Astrophysics Data System (ADS)

    Cheng, Ye; Zheng, Quan; Peng, Junkai; Lv, Pin; Zheng, Changwen

    2018-02-01

    The simulation of aerial flying targets is widely needed in many fields. This paper proposes a physically based method for optical simulation of flying targets. In the first step, three-dimensional target models are built and the motion speed and direction are defined. Next, the material of the outward appearance of a target is also simulated. Then the illumination conditions are defined. After all definitions are given, all settings are encoded in a description file. Finally, simulated results are generated by Monte Carlo ray tracing in a physically based renderer. Experiments show that this method is able to simulate materials, lighting and motion blur for flying targets, and it can generate convincing and highquality simulation results.

  18. Physical attractiveness, issue agreement, and assimilation effects in candidate appraisal.

    PubMed

    Schubert, James N; Curran, Margaret Ann; Strungaru, Carmen

    2011-01-01

    This study examines the cognitive and affective factors of candidate appraisal by manipulating candidate attractiveness and levels of issue agreement with voters. Drawing upon research in evolutionary psychology and cognitive neuroscience, this analysis proposes that automatic processing of physical appearance predisposes affective disposition toward more attractive candidates, thereby influencing cognitive processing of issue information. An experimental design presented attractive and unattractive candidates who were either liberal or conservative in a mock primary election. The data show strong partial effects for appearance on vote intention, an interaction between appearance and issue agreement, and a tendency for voters to assimilate the dissimilar views of attractive candidates. We argue that physical appearance is important in primary elections when the differences in issue positions and ideology between candidates is small.

  19. Practical Issues in Developing a Culturally Tailored Physical Activity Promotion Program for Chinese and Korean American Midlife Women: A Pilot Study

    PubMed Central

    Chee, Wonshik; Kim, Sangmi; Chu, Tsung-Lan; Ji, Xiaopeng; Zhang, Jingwen; Chee, Eunice; Im, Eun-Ok

    2016-01-01

    Background With advances in computer technologies, Web-based interventions are widely accepted and welcomed by health care providers and researchers. Although the benefits of Web-based interventions on physical activity promotion have been documented, the programs have rarely targeted Asian Americans, including Asian American midlife women. Subsequently, culturally competent Web-based physical activity programs for Asian Americans may be necessary. Objective The purpose of our study was to explore practical issues in developing and implementing a culturally competent Web-based physical activity promotion program for 2 groups of Asian American women—Chinese American and Korean American midlife women—and to provide implications for future research. Methods While conducting the study, the research team members wrote individual memos on issues and their inferences on plausible reasons for the issues. The team had group discussions each week and kept the minutes of the discussions. Then, the memos and minutes were analyzed using a content analysis method. Results We identified practical issues in 4 major idea categories: (1) bilingual translators’ language orientations, (2) cultural sensitivity requirement, (3) low response rate, interest, and retention, and (4) issues in implementation logistics. Conclusions Based on the issues, we make several suggestions for the use of bilingual translators, motivational strategies, and implementation logistics. PMID:27872035

  20. Kansas legislators prioritize obesity but overlook nutrition and physical activity issues.

    PubMed

    Heinrich, Katie M; Stephen, Mellina O; Vaughan, Katherine B; Kellogg, Melinda

    2013-01-01

    State-level policymakers play an important role in the fight against obesity because of their ability to create policies that influence opportunities for physical activity and nutrition. In 2011, we investigated how Kansas policymakers regarded obesity, nutrition, and physical activity in comparison to other issues. This study used a cross-sectional design. This study was conducted in Kansas, a predominately rural and Republican Midwestern state. All 181 state-level policymakers in Kansas were mailed a cover letter and survey. Policymakers were asked to identify and rate the importance of issues or problems in need of attention for Kansas. The 2011 state legislative report was content analyzed and coded to match the survey. Comparisons were made by political party. Of the 49 policymakers who completed a survey, 37 were Republicans and 43 were elected to their position. Although obesity-related issues were rated second highest after jobs, physical activity- and nutrition-related issues were not seen as important problems; moreover, little corresponding legislation was introduced. Other key issues identified by policymakers included budget/spending/taxes, education, jobs/economy, and drug abuse, with more legislation reflecting these problems. The Democrats ranked 11 issues as more significant problems than did the Republicans: quality of public education, poverty, access to health care, lack of affordable housing, ethics in government, lack of public health training, access to healthy groceries, lack of pedestrian walkways/crosswalks/sidewalks, pedestrian safety, air pollution, and global warming (P < .05). There is a need to provide more public health education on the relationship between nutrition and physical activity issues and obesity for Kansas policymakers. Issues identified may be similar for other predominately rural and Republican states.

  1. Research on Social Issues in Elementary School Physical Education

    ERIC Educational Resources Information Center

    Solmon, Melinda A.; Lee, Amelia M.

    2008-01-01

    The social and cultural norms children learn in schools can have a powerful effect on a variety of lifestyle decisions that will affect their physical and mental health. In this article we examine research on social issues in elementary school physical education. We provide an overview of how teachers' actions and behaviors affect what children…

  2. Her physics, his physics: gender issues in Israeli advanced placement physics classes

    NASA Astrophysics Data System (ADS)

    Zohar, Anat

    2003-02-01

    Gender gaps in physics in favour of boys are more prominent in Israel than in other countries. The main research question is to find out what gender issues are at play in Israeli advanced placement physics classes. Matriculation exam scores from approximately 400 high schools were analysed across 12 years. In addition, semi-constructed interviews were conducted with 50 advanced placement physics students (25 girls and 25 boys). In terms of participation, it was found that the ratio of girls to boys has been unchanged from 1988 to 2000 and is roughly 1:3. In terms of performance, it was found that the final matriculation scores of boys and girls are similar. However, breaking up the final scores into its two components - teachers' given grades and matriculation test scores - showed that boy's test scores are usually higher than girls' test scores, while girls' teachers' given grades are usually higher than boys'. Results from semi-constructed interviews pointed to two factors that are especially unfavourable to many girls: excessive competitiveness and lack of teaching for understanding. Girls' yearning for deep understanding is seen as a form of questing for connected knowledge. It is suggested that instructional methods that foster students' understanding while decreasing competitiveness in physics classes might contribute to girls' participation and performance in advanced physics classes while also supporting the learning of many boys.

  3. Outage management and health physics issue, 2007

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Agnihotri, Newal

    2007-05-15

    The focus of the May-June issue is on outage management and health physics. Major articles/reports in this issue include: India: a potential commercial opportunity, a U.S. Department of Commerce Report, by Joe Neuhoff and Justin Rathke; The changing climate for nuclear energy, by Skip Bowman, Nuclear Energy Insitute; Selecting protective clothing, by J. Mark Price, Southern California Edison; and Succssful refurbishment outage, by Sudesh K. Gambhir, Omaha Public Power District. Industry innovation articles in this issue are: Containment radiation monitoring spiking, by Michael W. Lantz and Robert Routolo, Arizona Public Service Company; Improved outage performance, by Michael Powell and Troymore » Wilfong, Arizona Public Service Company, Palo Verde Nuclear Generating Station; Stop repacking valves and achieve leak-free performance, by Kenneth Hart, PPL Susquehanna LLC; and Head assembly upgrade package, by Timothy Petit, Dominion Nuclear.« less

  4. Practical Issues in Developing a Culturally Tailored Physical Activity Promotion Program for Chinese and Korean American Midlife Women: A Pilot Study.

    PubMed

    Chee, Wonshik; Kim, Sangmi; Chu, Tsung-Lan; Tsai, Hsiu-Min; Ji, Xiaopeng; Zhang, Jingwen; Chee, Eunice; Im, Eun-Ok

    2016-11-21

    With advances in computer technologies, Web-based interventions are widely accepted and welcomed by health care providers and researchers. Although the benefits of Web-based interventions on physical activity promotion have been documented, the programs have rarely targeted Asian Americans, including Asian American midlife women. Subsequently, culturally competent Web-based physical activity programs for Asian Americans may be necessary. The purpose of our study was to explore practical issues in developing and implementing a culturally competent Web-based physical activity promotion program for 2 groups of Asian American women-Chinese American and Korean American midlife women-and to provide implications for future research. While conducting the study, the research team members wrote individual memos on issues and their inferences on plausible reasons for the issues. The team had group discussions each week and kept the minutes of the discussions. Then, the memos and minutes were analyzed using a content analysis method. We identified practical issues in 4 major idea categories: (1) bilingual translators' language orientations, (2) cultural sensitivity requirement, (3) low response rate, interest, and retention, and (4) issues in implementation logistics. Based on the issues, we make several suggestions for the use of bilingual translators, motivational strategies, and implementation logistics. ©Wonshik Chee, Sangmi Kim, Tsung-Lan Chu, Hsiu-Min Tsai, Xiaopeng Ji, Jingwen Zhang, Eunice Chee, Eun-Ok Im. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 21.11.2016.

  5. Neutrino physics today, important issues and the future

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Parke, Stephen J.; /Fermilab

    2010-10-01

    The status and the most important issues in neutrino physics will be summarized as well as how the current, pressing questions will be addressed by future experiments. Since the discovery of neutrino flavor transitions by the SuperKamiokande experiment in 1998, which demonstrates that neutrinos change and hence their clocks tick, i.e. they are not traveling at the speed of light and hence are not massless, the field of neutrino physics has made remarkable progress in untangling the nature of the neutrino. However, there are still many important questions to answer.

  6. Effects of Epstein's TARGET on adolescents' intentions to be physically active and leisure-time physical activity.

    PubMed

    Cecchini, Jose A; Fernandez-Rio, Javier; Mendez-Gimenez, Antonio

    2014-06-01

    The aim of this study was to examine the effects of Epstein's TARGET strategies on adolescents' intentions to be physically active and leisure-time physical activity (LTPA) levels. A total of 447 secondary education students (193 females and 254 males), range age 12-17 years, were divided in two groups: control (N = 224) and experimental (N = 223). Epstein's TARGET strategies were applied by especially trained teachers only to the experimental group in their physical education (PE) classes during 12 consecutive weeks. Participants' intentions to be physically active and their LTPA levels were assessed prior to the intervention (pre), at the end of it (post-1) and 3 months after the intervention (post-2). Significant increases were observed only in the experimental group in post-1 and post-2 on both variables. PE interventions based on TARGET strategies seem to be effective increasing adolescents' intentions to be physically active, as well as time spent in LTPA. As most adolescents participate in PE, these interventions could lead to substantial public health benefits. © The Author 2014. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  7. Quality of working life issues of employees with a chronic physical disease: a systematic review.

    PubMed

    de Jong, Merel; de Boer, Angela G E M; Tamminga, Sietske J; Frings-Dresen, Monique H W

    2015-03-01

    To assess issues that contribute to the Quality of Working Life (QWL) of employees with a chronic physical disease. A systematic literature search was conducted using the databases PubMed, PsycINFO and EMBASE. Experiences and perceptions during the working life of employees with a chronic physical disease were extracted and synthesized into issues that contributed to their QWL. We organized these synthesized QWL issues into higher order themes and categories with qualitative data analysis software. From a total of 4,044 articles identified by the search, 61 articles were included. Data extraction and data synthesis resulted in an overview of 73 QWL issues that were classified into 30 themes. The following five categories of themes were identified: (1) job characteristics with issues such as job flexibility and work-site access; (2) the social structure and environment containing issues about disclosure, discrimination, misunderstanding, and awareness by employers or colleagues; (3) organizational characteristics with issues such as requesting work accommodations; (4) individual work perceptions including issues about enjoyment and evaluating work or life priorities; and (5) effect of the disease and treatment including issues about cognitive and physical health and work ability. This systematic review offers an extensive overview of issues that might contribute to the QWL of employees with a chronic physical disease. This overview may function as a starting point for occupational support, such as monitoring and evaluating the QWL of employees with a chronic physical disease during return-to-work and work continuation processes.

  8. Practical issues of biomarker-assisted targeted therapy in precision medicine and immuno-oncology era.

    PubMed

    Lee, Dae Ho

    2018-01-01

    The concept of precision medicine is not new, as multiplex and very sensitive methods, or next-generation sequencing and matched targeted cancer therapies, have come to clinical practice. Substantial progress has been made from the discovery to the development and clinical application of biomarkers and matched targeted therapies. However, there still remain many challenges and issues to be overcome in each step, from acquisition of tumour tissues through validation of biomarkers to the final decision on targeted therapy. This review will briefly touch on these issues, hoping to provide a better understanding and application of targeted therapy in cancer treatment in the era of precision medicine and immuno-oncology. It also helps to understand that the meaning or value of biomarker(s) and matched targeted therapy changes along with expansion of knowledge and advance of methodology, and constant efforts have to be made in evaluating the meaning and clinical value during the development and after the establishment of biomarkers or the approval of matched targeted therapies, which might be more complicated by the advent of new therapeutic agents and new diagnostic methods.

  9. Examining issues of underrepresented minority students in introductory physics

    NASA Astrophysics Data System (ADS)

    Watkins, Jessica Ellen

    In this dissertation we examine several issues related to the retention of under-represented minority students in physics and science. In the first section, we show that in calculus-based introductory physics courses, the gender gap on the FCI is diminished through the use of interactive techniques, but in lower-level introductory courses, the gap persists, similar to reports published at other institutions. We find that under-represented racial minorities perform similar to their peers with comparable academic preparation on conceptual surveys, but their average exam grades and course grades are lower. We also examine student persistence in science majors; finding a significant relationship between pedagogy in an introductory physics course and persistence in science. In the second section, we look at student end-of-semester evaluations and find that female students rate interactive teaching methods a full point lower than their male peers. Looking more deeply at student interview data, we find that female students report more social issues related to the discussions in class and both male and female students cite feeling pressure to obtain the correct answer to clicker questions. Finally, we take a look an often-cited claim for gender differences in STEM participation: cognitive differences explain achievement differences in physics. We examine specifically the role of mental rotations in physics achievement and problem-solving, viewing mental rotations as a tool that students can use on physics problems. We first look at student survey results for lower-level introductory students, finding a low, but significant correlation between performance on a mental rotations test and performance in introductory physics courses. In contrast, we did not find a significant relationship for students in the upper-level introductory course. We also examine student problem-solving interviews to investigate the role of mental rotations on introductory problems.

  10. Topics in LIFE Target Survival: 11-SI-004 Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miles, Robin; Benett, Bill; Bond, Tiziana

    The LIFE target design incorporates many considerations to generate the desired fusion gain including the physics design, the cost of manufacturing of the target, the injectability of the target, the aerodynamic flight characteristics of the target, the ability to track and engage the target and to maintain the structural and thermal integrity of the target. This document describes the effort that was made in support of issues of survivability of the target during injection which included issues massmanufactural materials and processes which could be used in the target.

  11. Introduction to the special issue Hermann Weyl and the philosophy of the 'New Physics'

    NASA Astrophysics Data System (ADS)

    De Bianchi, Silvia; Catren, Gabriel

    2018-02-01

    This Special Issue Hermann Weyl and the Philosophy of the 'New Physics' has two main objectives: first, to shed fresh light on the relevance of Weyl's work for modern physics and, second, to evaluate the importance of Weyl's work and ideas for contemporary philosophy of physics. Regarding the first objective, this Special Issue emphasizes aspects of Weyl's work (e.g. his work on spinors in n dimensions) whose importance has recently been emerging in research fields across both mathematical and experimental physics, as well as in the history and philosophy of physics. Regarding the second objective, this Special Issue addresses the relevance of Weyl's ideas regarding important open problems in the philosophy of physics, such as the problem of characterizing scientific objectivity and the problem of providing a satisfactory interpretation of fundamental symmetries in gauge theories and quantum mechanics. In this Introduction, we sketch the state of the art in Weyl studies and we summarize the content of the contributions to the present volume.

  12. Thin-thick hydrogen target for nuclear physics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gheller, J.-M.; Juster, F.-P.; Authelet, G.

    In spectroscopic studies of unstable nuclei, hydrogen targets are of key importance. The CHyMENE Project aims to provide to the nuclear physics community a thin and pure solid windowless hydrogen or deuterium target. CHyMENE project must respond to this request for the production of solid Hydrogen. The solid hydrogen target is produced in a continuous flow (1 cm/s) by an extrusion technique (developed with the PELIN laboratory) in a vacuum chamber. The shape of the target is determined by the design of the nozzle at the extrusion process. For the purpose, the choice is a rectangular shape with a widthmore » of 10 mm and a thickness in the range of 30-50 microns necessary for the physics objectives. The cryostat is equipped with a GM Cryocooler with sufficient power for the solidification of the hydrogen in the lower portion of the extruder. In the higher part of the cryostat, the hydrogen gas is first liquefied and partially solidified. It is then compressed at 100 bars in the cooled extruder before expulsion of the film through the nozzle at the center of the reaction vacuum chamber. After the previous step, the solid hydrogen ribbon falls by gravity into a dedicated chamber where it sublimes and the gas is pumped and evacuated in a exhaust line. This paper deals with the design of the cryostat with its equipment, with the sizing of the thermal bridge (Aluminum and copper), with the results regarding the contact resistance as well as with the vacuum computations of the reaction and recovery hydrogen gas chambers.« less

  13. Statistical issues in searches for new phenomena in High Energy Physics

    NASA Astrophysics Data System (ADS)

    Lyons, Louis; Wardle, Nicholas

    2018-03-01

    Many analyses of data in High Energy Physics are concerned with searches for New Physics. We review the statistical issues that arise in such searches, and then illustrate these using the specific example of the recent successful search for the Higgs boson, produced in collisions between high energy protons at CERN’s Large Hadron Collider.

  14. The Target Income Hypothesis and Related Issues in Health Manpower Policy.

    ERIC Educational Resources Information Center

    Health Resources Administration (DHEW/PHS), Bethesda, MD. Bureau of Health Manpower.

    The target income hypothesis as applied to health personnel is discussed in seven papers and three commentaries. The hypothesis pertains to the economic behavior of physicians, and it has recently been applied to dentists as well. The issues concern the production/supply of practitioners and the resulting cost for their services. Whether…

  15. Targeting and tailoring physical activity information using print and information technologies.

    PubMed

    Napolitano, Melissa A; Marcus, Bess H

    2002-07-01

    With the large numbers of physically inactive individuals, it is important that interventions reach a broad spectrum of the population. This paper focuses on targeting and tailoring physical activity information, and the use of mediated interventions, specifically those using print, and other information technologies for promoting physical activity.

  16. Physics opportunities with a fixed target experiment at the LHC (AFTER@LHC)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hadjidakis, Cynthia; Anselmino, Mauro; Arnaldi, R.

    By extracting the beam with a bent crystal or by using an internal gas target, the multi-TeV proton and lead LHC beams allow one to perform the most energetic fixed-target experiments (AFTER@LHC) and to study p+p and p+A collisions at \\sqrt{s_NN}=115 GeV and Pb+p and Pb+A collisions at \\sqrt{s_NN}=72 GeV. Such studies would address open questions in the domain of the nucleon and nucleus partonic structure at high-x, quark-gluon plasma and, by using longitudinally or transversally polarised targets, spin physics. In this paper, we discuss the physics opportunities of a fixed-target experiment at the LHC and we report on themore » possible technical implementations of a high-luminosity experiment. We finally present feasibility studies for Drell-Yan, open heavy-flavour and quarkonium production, with an emphasis on high-x and spin physics.« less

  17. Continuing education in physical rehabilitation and health issues of agricultural workers.

    PubMed

    Wilhite, Carla S; Jaco, Linda

    2014-01-01

    Limited attention has been devoted to the cultural and practice competencies needed by occupational therapy and physical therapy professionals who provide services to farming families impacted by chronic health or disability issues. Agricultural occupational safety and health should represent a continuum of services responsive to individuals, families, and agricultural communities across a life span and range of health status changes. Physical rehabilitation professionals have a key role in impacting an agricultural producer's sense of self-efficacy and capacities for returning to agricultural living and work. However, demonstration of competency is essential in providing person-centered rehabilitation services of assessment, evaluation, treatment planning, interventions, referrals, and discharge issues. The paper highlights methods utilized by a state AgrAbility program and a former National AgrAbility Project to develop a model of continuing education programming for occupational and physical therapists that evaluate and treat agricultural workers after acute injury or exacerbation of chronic health conditions.

  18. Integration of Environmental Issues in a Physics Course: 'Physics by Inquiry' High School Teachers' Integration Models and Challenges

    NASA Astrophysics Data System (ADS)

    Kimori, David Abiya

    As we approach the second quarter of the twenty-first century, one may predict that the environment will be among the dominant themes in the political and educational discourse. Over the past three decades, particular perspectives regarding the environment have begun to emerge: (i) realization by human beings that we not only live on earth and use its resources at an increasingly high rate but we also actually belong to the earth and the total ecology of all living systems, (ii) there are strong interactions among different components of the large and complex systems that make up our environment, and (iii) the rising human population and its impact on the environment is a great concern (Hughes & Mason, 2014). Studies have revealed that although the students do not have a deep understanding of environmental issues and lack environmental awareness and attitudes necessary for protecting the environment, they have great concern for the environment (Chapman & Sharma, 2001; Fien, Yencken, & Sykes, 2002). However, addressing environmental issues in the classroom and other disciplines has never been an easy job for teachers (Pennock & Bardwell, 1994; Edelson, 2007). Using multiple case studies, this study investigated how three purposefully selected physics teachers teaching a 'Physics by Inquiry' course integrated environmental topics and issues in their classroom. Particularly this study looked at what integration models and practices the three physics teachers employed in integrating environmental topics and issues in their classroom and what challenges the teachers faced while integrating environmental topics in their classrooms. Data collection methods including field notes taken from observations, teachers' interviews and a collection of artifacts and documents were used. The data were coded analyzed and organized into codes and categories guided by Fogarty (1991) models of curriculum integration and Ham and Sewing (1988) four categories of barriers to environmental

  19. Target R and D for high power proton beam applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fabich, A.

    High power targets are one of the major issues in an accelerator complex for future HEP physic studies. The paper will review status of studies worldwide. It will focus on the status of the MERIT mercury-jet target experiment at CERN.

  20. Bypassing Protein Corona Issue on Active Targeting: Zwitterionic Coatings Dictate Specific Interactions of Targeting Moieties and Cell Receptors.

    PubMed

    Safavi-Sohi, Reihaneh; Maghari, Shokoofeh; Raoufi, Mohammad; Jalali, Seyed Amir; Hajipour, Mohammad J; Ghassempour, Alireza; Mahmoudi, Morteza

    2016-09-07

    Surface functionalization strategies for targeting nanoparticles (NP) to specific organs, cells, or organelles, is the foundation for new applications of nanomedicine to drug delivery and biomedical imaging. Interaction of NPs with biological media leads to the formation of a biomolecular layer at the surface of NPs so-called as "protein corona". This corona layer can shield active molecules at the surface of NPs and cause mistargeting or unintended scavenging by the liver, kidney, or spleen. To overcome this corona issue, we have designed biotin-cysteine conjugated silica NPs (biotin was employed as a targeting molecule and cysteine was used as a zwitterionic ligand) to inhibit corona-induced mistargeting and thus significantly enhance the active targeting capability of NPs in complex biological media. To probe the targeting yield of our engineered NPs, we employed both modified silicon wafer substrates with streptavidin (i.e., biotin receptor) to simulate a target and a cell-based model platform using tumor cell lines that overexpress biotin receptors. In both cases, after incubation with human plasma (thus forming a protein corona), cellular uptake/substrate attachment of the targeted NPs with zwitterionic coatings were significantly higher than the same NPs without zwitterionic coating. Our results demonstrated that NPs with a zwitterionic surface can considerably facilitate targeting yield of NPs and provide a promising new type of nanocarriers in biological applications.

  1. The stress of food allergy issues in daily life.

    PubMed

    Peniamina, Rana L; Mirosa, Miranda; Bremer, Philip; Conner, Tamlin S

    2016-06-01

    Food allergies are a growing health concern, but their implications for daily psychological functioning are unknown. This micro-longitudinal study investigated the daily frequency of food allergy issues and how this related to experiences of stress, mood and physical energy. One hundred and eight adults with physician-diagnosed food allergies completed an initial Internet survey followed by a 2-week Internet daily diary survey. The initial survey collected socio-demographic and food allergy information. The daily survey collected information about the participants' experiences of stress, mood, physical energy and food allergy issues during that day. Commonly experienced allergy issues included negative physical symptoms, higher food prices, anxiety about safety of food, trouble maintaining a healthy diet and anxiety/stress at social occasions. Furthermore, multilevel modelling analyses showed that stress and negative mood were significantly higher on days with more allergy issues. Older adults experienced lower positive mood and physical energy on days with more issues. This is the first study to incorporate near to real-time tracking to examine the frequency of food allergy issues and the implications for daily psychological functioning. Targeting the issues we identified could reduce stress in patients with food allergies and improve their overall quality of life.

  2. An investigation of how university sports team athletic therapists and physical therapists experience ethical issues.

    PubMed

    Riendeau, Catherine; Parent-Houle, Valérie; Lebel-Gabriel, Marie Eve; Gauvin, Patrick; Liu, Le Yu; Pearson, Isabelle; Hunt, Matthew R

    2015-03-01

    Qualitative study using interpretive description methodology. The purpose of this study was to better understand how ethical issues are experienced by university sports team athletic therapists and physical therapists. In clinical practice, sports teams are associated with a range of ethical issues. Issues commonly reported in the literature include confidentiality, return-to-play decisions, conflicts of interest, advertising, doping, and use of local anesthetic. To date, there has been limited examination of how athletic therapists and physical therapists involved with sports teams experience these ethical issues, and limited exploration of how these ethical issues, when encountered, are shaped by therapists' professional roles and responsibilities. Semi-structured interviews were conducted with 11 athletic or physical therapists working with sports teams in 5 Canadian provinces. The data were analyzed inductively, using a recursive approach and constant comparative techniques. Four key themes were developed relating to the participants' experiences of ethical issues: establishing and maintaining professional boundaries, striving for respectful and effective collaboration, seeking answers to ethical concerns, and living with the repercussions of challenging decisions. While many ethical issues reported by participants resemble those faced by sports medicine physicians, they are experienced in distinctive ways, due to differences in professional roles and identities. Issues concerning professional boundaries were also more prominent for the study participants than the literature has reported them to be for sports medicine physicians. Effective communication and enhanced collaboration appear to be key elements in managing these ethical challenges.

  3. The Issues Framework: Situating Graduate Teaching Assistant-Student Interactions in Physics Problem Solving

    NASA Astrophysics Data System (ADS)

    Westlander, Meghan Joanne

    Interactive engagement environments are critical to students' conceptual learning gains, and often the instructor is ultimately responsible for the creation of that environment in the classroom. When those instructors are graduate teaching assistants (GTAs), one of the primary ways in which they can promote interactive engagement is through their interactions with students. Much of the prior research on physics GTA-student interactions focuses on GTA training programs (e.g. Ezrailson (2004); Smith, Ward, and Rosenshein (1977)) or on GTAs' specific actions and beliefs (e.g. West, Paul, Webb, and Potter (2013); Goertzen (2010); Spike and Finkelstein (2012a)). Research on students' ideas and behaviors within and surrounding those interactions is limited but important to obtaining a more complete understanding of how GTAs promote an interactive environment. In order to begin understanding this area, I developed the Issues Framework to examine how GTA-student interactions are situated in students' processes during physics problem solving activities. Using grounded theory, the Issues Framework emerged from an analysis of the relationships between GTA-student interactions and the students procedures and expressions of physics content in and surrounding those interactions. This study is focused on introducing the Issues Framework and the insight it can provide into GTA-student interactions and students' processes. The framework is general in nature and has a visually friendly design making it a useful tool for consolidating complex data and quickly pattern-matching important pieces of a complex process. Four different categories of Issues emerged spanning the problem solving process: (1) Getting Started, (2) Solution Approach, (3) Unit Conversions, and (4) Other. The framework allowed for identification of the specific contents of the Issues in each category as well as revealing the common stories of students' processes and how the interactions were situated in those

  4. Optimizing targeted vaccination across cyber-physical networks: an empirically based mathematical simulation study.

    PubMed

    Mones, Enys; Stopczynski, Arkadiusz; Pentland, Alex 'Sandy'; Hupert, Nathaniel; Lehmann, Sune

    2018-01-01

    Targeted vaccination, whether to minimize the forward transmission of infectious diseases or their clinical impact, is one of the 'holy grails' of modern infectious disease outbreak response, yet it is difficult to achieve in practice due to the challenge of identifying optimal targets in real time. If interruption of disease transmission is the goal, targeting requires knowledge of underlying person-to-person contact networks. Digital communication networks may reflect not only virtual but also physical interactions that could result in disease transmission, but the precise overlap between these cyber and physical networks has never been empirically explored in real-life settings. Here, we study the digital communication activity of more than 500 individuals along with their person-to-person contacts at a 5-min temporal resolution. We then simulate different disease transmission scenarios on the person-to-person physical contact network to determine whether cyber communication networks can be harnessed to advance the goal of targeted vaccination for a disease spreading on the network of physical proximity. We show that individuals selected on the basis of their closeness centrality within cyber networks (what we call 'cyber-directed vaccination') can enhance vaccination campaigns against diseases with short-range (but not full-range) modes of transmission. © 2018 The Author(s).

  5. Cognitive Issues in Learning Advanced Physics: An Example from Quantum Mechanics

    NASA Astrophysics Data System (ADS)

    Singh, Chandralekha; Zhu, Guangtian

    2009-11-01

    We are investigating cognitive issues in learning quantum mechanics in order to develop effective teaching and learning tools. The analysis of cognitive issues is particularly important for bridging the gap between the quantitative and conceptual aspects of quantum mechanics and for ensuring that the learning tools help students build a robust knowledge structure. We discuss the cognitive aspects of quantum mechanics that are similar or different from those of introductory physics and their implications for developing strategies to help students develop a good grasp of quantum mechanics.

  6. Noncoherent Physical-Layer Network Coding with FSK Modulation: Relay Receiver Design Issues

    DTIC Science & Technology

    2011-03-01

    222 IEEE TRANSACTIONS ON COMMUNICATIONS, VOL. 59, NO. 9, SEPTEMBER 2011 2595 Noncoherent Physical-Layer Network Coding with FSK Modulation: Relay... noncoherent reception, channel estima- tion. I. INTRODUCTION IN the two-way relay channel (TWRC), a pair of sourceterminals exchange information...2011 4. TITLE AND SUBTITLE Noncoherent Physical-Layer Network Coding with FSK Modulation:Relay Receiver Design Issues 5a. CONTRACT NUMBER 5b

  7. Introduction to the issue on Physics and Applications of Laser Dynamics (IS-PALD 2013).

    PubMed

    Grillot, Frédéric; Sciamanna, Marc; Chen, Yung-Fu

    2014-03-24

    We introduce the Optics Express special issue of the 3rd symposium on Physics and Applications of Laser Dynamics (IS-PALD). This issue consists of expanded papers related to oral and poster presentations. Selected papers represent the best of IS-PALD 2013.

  8. Target effect on the kinematics of Taekwondo Roundhouse Kick - is the presence of a physical target a stimulus, influencing muscle-power generation?

    PubMed

    Wąsik, Jacek; Shan, Gongbing

    2015-01-01

    Taekwondo is famous for its powerful kicking techniques and the roundhouse kick is the most frequently used one. In earlier literature, the influence of a physical target (exiting or not) on kicking power generation has not been given much attention. Therefore, the aim of this study was to investigate the kinematics of roundhouse kick execution and its factors related to power generation. 6 ITF taekwondo practitioners voluntarily participated in this study. They were asked to perform kicks with and without a physical target. The first kick aimed at breaking a board while the second one was a kick into the air. A Smart-D motion capture system (BTS S.p.A., Italy) was used to quantitatively determine their kinematic characteristics during each kick. The main findings showed that kicks aiming at a breaking board were significantly slower than kicks without a physical target (maximal kick-foot velocities were 10.61 ± 0.86 m/s and 14.61 ± 0.67 m/s, respectively, p < 0.01), but the kicking time of the former was shorter (0.58 ± 0.01 s and 0.67 ± 0.01, respectively, p < 0.01). The results suggest that a physical target will negatively influence the kick-foot velocity, which is not necessarily a disadvantage for creating a high quality kick. Possible motor control mechanisms are discussed for the phenomenon. The study made it clear: trainings with and without physical targets would develop different motor control patterns. More studies are needed for identifying the effectiveness of different controls and efficiencies of their training.

  9. Body image and self-esteem among adolescents undergoing an intervention targeting dietary and physical activity behaviors.

    PubMed

    Huang, Jeannie S; Norman, Gregory J; Zabinski, Marion F; Calfas, Karen; Patrick, Kevin

    2007-03-01

    To determine the effect of a one-year intervention targeting physical activity, sedentary, and diet behaviors among adolescents on self-reported body image and self-esteem. Health promotion interventions can lead to awareness of health risk and subsequent adoption of beneficial changes in behavior. However, it is possible that interventions targeting behaviors associated with childhood obesity may also increase the likelihood of unhealthy eating and physical activity obsessions and behaviors. Body image and self-esteem were assessed for adolescents participating in the PACE+ study, a randomized controlled trial of a 1-year behavioral intervention targeting physical activity, sedentary, and dietary behaviors. The Body Dissatisfaction subscale of the Eating Disorder Inventory and Rosenberg Self-Esteem scale were used to assess body image and self-esteem, respectively, and measurements were performed at baseline, and at 6 and 12 months. Demographic characteristics and weight status of participants were also ascertained. Analysis of responses was performed via both between-group and within-group repeated measure analyses. There were 657 adolescents who completed all measurements. Body image differences were found for age, gender, and weight status at baseline, whereas self-esteem differences were demonstrated for gender, ethnicity, and weight status. There were no intervention effects on body image or self-esteem for either girls or boys. Self-esteem and body satisfaction did not worsen as a result of participating in the PACE+ intervention for either boys or girls whether or not they lost or maintained their weight or gained weight. Girls assigned to the PACE intervention who experienced weight reduction or weight maintenance at either 6 or 12 months reported improvements in body image satisfaction (p = .02) over time compared with subjects who had experienced weight gain during the 12-month study period. Adverse effects on body satisfaction and self-esteem were not

  10. Body Image and Self-Esteem among Adolescents undergoing an Intervention Targeting Dietary and Physical Activity Behaviors

    PubMed Central

    Huang, Jeannie S.; Norman, Gregory J.; Zabinski, Marion F.; Calfas, Karen; Patrick, Kevin

    2007-01-01

    Background Health promotion interventions can lead to awareness of health risk and subsequent adoption of beneficial changes in behavior. However, it is possible that interventions targeting behaviors associated with childhood obesity may also increase the likelihood of unhealthy eating and physical activity obsessions and behaviors. Objective To determine the effect of a one-year intervention targeting physical activity, sedentary and diet behaviors among adolescents on self-reported body image and self-esteem. Methods Body image and self-esteem were assessed for adolescents participating in the PACE+ study, a randomized controlled trial of a one-year behavioral intervention targeting physical activity, sedentary, and dietary behaviors. The Body Dissatisfaction subscale of the Eating Disorder Inventory and Rosenberg Self-Esteem scale were used to assess body image and self-esteem respectively, and measurements were performed at baseline, 6 and 12 months. Demographic characteristics and weight status of participants were also ascertained. Analysis of responses was performed via both between-group and within-group repeated measure analyses. Results 657 adolescents completed all measurements. Body image differences were found for age, sex and weight status at baseline, while self-esteem differences were demonstrated for sex, ethnicity and weight status. There were no intervention effects on body image or self-esteem for either girls or boys. Self-esteem and body satisfaction did not worsen as a result of participating in the PACE+ intervention for either boys or girls whether or not they lost or maintained their weight or gained weight. Girls assigned to the PACE intervention who experienced weight reduction or weight maintenance at either 6 or 12-months reported improvements in body image satisfaction (p=0.02) over time compared to subjects who had experienced weight gain during the 12-month study period. Conclusions Adverse effects on body satisfaction and self

  11. Ethically-based clinical decision-making in physical therapy: process and issues.

    PubMed

    Finch, Elspeth; Geddes, E Lynne; Larin, Hélène

    2005-01-01

    The identification and consideration of relevant ethical issues in clinical decision-making, and the education of health care professionals (HCPs) in these skills are key factors in providing quality health care. This qualitative study explores the way in which physical therapists (PTs) integrate ethical issues into clinical practice decisions and identifies ethical themes used by PTs. A purposive sample of eight PTs was asked to describe a recent ethically-based clinical decision. Transcribed interviews were coded and themes identified related to the following categories: 1) the integration of ethical issues in the clinical decision-making process, 2) patient welfare, 3) professional ethos of the PT, and 4) health care economics and business practices. Participants readily described clinical situations involving ethical issues but rarely identified specific conflicting ethical issues in their description. Ethical dilemmas were more frequently resolved when there were fewer emotional sequelae associated with the dilemma, and the PT had a clear understanding of professional ethos, valued patient autonomy, and explored a variety of alternative actions before implementing one. HCP students need to develop a clear professional ethos and an increased understanding of the economic factors that will present ethical issues in practice.

  12. Comparison of accelerator physics issues for symmetric and asymmetric B-factory rings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tigner, M.

    1990-10-10

    A systematic comparison of accelerator physics issues from the beam-beam interaction to single particle stability including ring and IR layout, synchrotron radiation and lost particle backgrounds, and single and multi-bunch instabilities is given. While some practical handicap probably accrues to the asymmetric design because of its extra constraints, the differences in the two approaches tend to be obscured by larger issues such as how to achieve the enormous increases in luminosity demanded of a b-factory.

  13. Key issues and technical route of cyber physical distribution system

    NASA Astrophysics Data System (ADS)

    Zheng, P. X.; Chen, B.; Zheng, L. J.; Zhang, G. L.; Fan, Y. L.; Pei, T.

    2017-01-01

    Relying on the National High Technology Research and Development Program, this paper introduced the key issues in Cyber Physical Distribution System (CPDS), mainly includes: composite modelling method and interaction mechanism, system planning method, security defence technology, distributed control theory. Then on this basis, the corresponding technical route is proposed, and a more detailed research framework along with main schemes to be adopted is also presented.

  14. Manufacturing of calcium, lithium and molybdenum targets for use in nuclear physics experiments

    NASA Astrophysics Data System (ADS)

    Kheswa, N. Y.; Papka, P.; Buthelezi, E. Z.; Lieder, R. M.; Neveling, R.; Newman, R. T.

    2010-02-01

    This paper describes methods used in the manufacturing of chemically reactive targets such as calcium ( natCa), lithium-6 ( 6Li) and molybdenum-97 ( 97Mo) for nuclear physics experiments at the iThemba LABS cyclotron facility (Faure, South Africa). Due to the chemical properties of these materials a suitable and controlled environment was established in order to minimize oxygen contamination of targets. Calcium was prepared by means of vacuum evaporation while lithium was cold rolled to a desired thickness. In the case of molybdenum, the metallic powder was melted under vacuum using an e-gun followed by cold rolling of the metal bead to a desired thickness. In addition, latest developments toward the establishment of a dedicated nuclear physics target laboratory are discussed.

  15. Impact of an Australian mass media campaign targeting physical activity in 1998.

    PubMed

    Bauman, A E; Bellew, B; Owen, N; Vita, P

    2001-07-01

    Physical activity is now a public health priority, but there is only limited evidence on the effectiveness of mass-reach campaigns. Paid and unpaid television and print-media advertising, physician mail-outs, and community-level support programs and strategies. A mass-media statewide campaign to promote regular moderate-intensity activity was conducted during February 1998. The target group was adults aged 25 to 60 who were motivated but insufficiently active. Cohort and independent-sample, cross-sectional representative population surveys, before and after the campaign. The intervention was conducted in the state of New South Wales, with the other states of Australia as the comparison region. Telephone survey items on physical activity, media message awareness, physical activity knowledge, self-efficacy, and intentions. Unprompted recall of the activity messages in the campaign state increased substantially from 2.1% to 20.9% (p<0.01), with small changes elsewhere in Australia (1.2% to 2.6%). There were large changes in prompted awareness from 12.9% to 50.7% (p<0.0001), much larger than changes elsewhere (14.1% to 16%, p=0.06). Knowledge of appropriate moderate-intensity activity and physical activity self-efficacy increased significantly and only in the campaign state. Compared to all others, those in the target group who recalled the media message were 2.08 times more likely to increase their activity by at least an hour per week (95% confidence interval = 1.51-2.86). This integrated campaign positively influenced short-term physical activity message recall, knowledge, and behavior of the target population, compared to the population in the region who were not exposed.

  16. Contemporary Issues of Social Justice: A Focus on Race and Physical Education in the United States.

    PubMed

    Harrison, Louis; Clark, Langston

    2016-09-01

    Ongoing events in the United States show the continual need to address issues of social justice in every social context. Of particular note in this article, the contemporary national focus on race has thrust social justice issues into the forefront of the country's conscious. Although legal segregation has ran its course, schools and many neighborhoods remain, to a large degree, culturally, ethnically, linguistically, economically, and racially segregated and unequal (Orfield & Lee, 2005). Even though an African American president presently occupies the White House, the idea of a postracial America remains an unrealized ideal. Though social justice and racial discussions are firmly entrenched in educational research, investigations that focus on race are scant in physical education literature. Here, we attempt to develop an understanding of social justice in physical education with a focus on racial concerns. We purposely confine the examination to the U.S. context to avoid the dilution of the importance of these issues, while recognizing other international landscapes may differ significantly. To accomplish this goal, we hope to explicate the undergirding theoretical tenants of critical race theory and culturally relevant pedagogy in relation to social justice in physical education. Finally, we make observations of social justice in the physical education and physical education teacher education realms to address and illuminate areas of concern.

  17. Effects of Epstein's TARGET on Adolescents' Intentions to Be Physically Active and Leisure-Time Physical Activity

    ERIC Educational Resources Information Center

    Cecchini, Jose A.; Fernandez-Rio, Javier; Mendez-Gimenez, Antonio

    2014-01-01

    The aim of this study was to examine the effects of Epstein's TARGET strategies on adolescents' intentions to be physically active and leisure-time physical activity (LTPA) levels. A total of 447 secondary education students (193 females and 254 males), range age 12-17 years, were divided in two groups: control (N = 224) and experimental…

  18. Teaching with Socio-Scientific Issues in Physical Science: Teacher and Students' Experiences

    ERIC Educational Resources Information Center

    Talens, Joy

    2016-01-01

    Socio-scientific issues (SSI) are recommended by many science educators worldwide for learners to acquire first hand experience to apply what they learned in class. This investigated experiences of teacher-researcher and students in using SSI in Physical Science, Second Semester, School Year 2012-2013. Latest and controversial news articles on…

  19. Pharmacological and Physical Vessel Modulation Strategies to Improve EPR-mediated Drug Targeting to Tumors

    PubMed Central

    Ojha, Tarun; Pathak, Vertika; Shi, Yang; Hennink, Wim; Moonen, Chrit; Storm, Gert; Kiessling, Fabian; Lammers, Twan

    2018-01-01

    The performance of nanomedicine formulations depends on the Enhanced Permeability and Retention (EPR) effect. Prototypic nanomedicine-based drug delivery systems, such as liposomes, polymers and micelles, aim to exploit the EPR effect to accumulate at pathological sites, to thereby improve the balance between drug efficacy and toxicity. Thus far, however, tumor-targeted nanomedicines have not yet managed to achieve convincing therapeutic results, at least not in large cohorts of patients. This is likely mostly due to high inter- and intra-patient heterogeneity in EPR. Besides developing (imaging) biomarkers to monitor and predict EPR, another strategy to address this heterogeneity is the establishment of vessel modulation strategies to homogenize and improve EPR. Over the years, several pharmacological and physical co-treatments have been evaluated to improve EPR-mediated tumor targeting. These include pharmacological strategies, such as vessel permeabilization, normalization, disruption and promotion, as well as physical EPR enhancement via hyperthermia, radiotherapy, sonoporation and phototherapy. In the present manuscript, we summarize exemplary studies showing that pharmacological and physical vessel modulation strategies can be used to improve tumor-targeted drug delivery, and we discuss how these advanced combination regimens can be optimally employed to enhance the (pre-) clinical performance of tumor-targeted nanomedicines. PMID:28697952

  20. Pharmacological and physical vessel modulation strategies to improve EPR-mediated drug targeting to tumors.

    PubMed

    Ojha, Tarun; Pathak, Vertika; Shi, Yang; Hennink, Wim E; Moonen, Chrit T W; Storm, Gert; Kiessling, Fabian; Lammers, Twan

    2017-09-15

    The performance of nanomedicine formulations depends on the Enhanced Permeability and Retention (EPR) effect. Prototypic nanomedicine-based drug delivery systems, such as liposomes, polymers and micelles, aim to exploit the EPR effect to accumulate at pathological sites, to thereby improve the balance between drug efficacy and toxicity. Thus far, however, tumor-targeted nanomedicines have not yet managed to achieve convincing therapeutic results, at least not in large cohorts of patients. This is likely mostly due to high inter- and intra-patient heterogeneity in EPR. Besides developing (imaging) biomarkers to monitor and predict EPR, another strategy to address this heterogeneity is the establishment of vessel modulation strategies to homogenize and improve EPR. Over the years, several pharmacological and physical co-treatments have been evaluated to improve EPR-mediated tumor targeting. These include pharmacological strategies, such as vessel permeabilization, normalization, disruption and promotion, as well as physical EPR enhancement via hyperthermia, radiotherapy, sonoporation and phototherapy. In the present manuscript, we summarize exemplary studies showing that pharmacological and physical vessel modulation strategies can be used to improve tumor-targeted drug delivery, and we discuss how these advanced combination regimens can be optimally employed to enhance the (pre-) clinical performance of tumor-targeted nanomedicines. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. Physics considerations in targeted anticancer drug delivery by magnetoelectric nanoparticles

    NASA Astrophysics Data System (ADS)

    Stimphil, Emmanuel; Nagesetti, Abhignyan; Guduru, Rakesh; Stewart, Tiffanie; Rodzinski, Alexandra; Liang, Ping; Khizroev, Sakhrat

    2017-06-01

    In regard to cancer therapy, magnetoelectric nanoparticles (MENs) have proven to be in a class of its own when compared to any other nanoparticle type. Like conventional magnetic nanoparticles, they can be used for externally controlled drug delivery via application of a magnetic field gradient and image-guided delivery. However, unlike conventional nanoparticles, due to the presence of a non-zero magnetoelectric effect, MENs provide a unique mix of important properties to address key challenges in modern cancer therapy: (i) a targeting mechanism driven by a physical force rather than antibody matching, (ii) a high-specificity delivery to enhance the cellular uptake of therapeutic drugs across the cancer cell membranes only, while sparing normal cells, (iii) an externally controlled mechanism to release drugs on demand, and (iv) a capability for image guided precision medicine. These properties separate MEN-based targeted delivery from traditional biotechnology approaches and lay a foundation for the complementary approach of technobiology. The biotechnology approach stems from the underlying biology and exploits bioinformatics to find the right therapy. In contrast, the technobiology approach is geared towards using the physics of molecular-level interactions between cells and nanoparticles to treat cancer at the most fundamental level and thus can be extended to all the cancers. This paper gives an overview of the current state of the art and presents an ab initio model to describe the underlying mechanisms of cancer treatment with MENs from the perspective of basic physics.

  2. Outage management and health physics issue, 2009

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Agnihotri, Newal

    2009-05-15

    The focus of the May-June issue is on outage management and health physics. Major articles include the following: Planning and scheduling to minimize refueling outage, by Pat McKenna, AmerenUE; Prioritizing safety, quality and schedule, by Tom Sharkey, Dominion; Benchmarking to high standards, by Margie Jepson, Energy Nuclear; Benchmarking against U.S. standards, by Magnox North, United Kingdom; Enabling suppliers for new build activity, by Marcus Harrington, GE Hitachi Nuclear Energy; Identifying, cultivating and qualifying suppliers, by Thomas E. Silva, AREVA NP; Creating new U.S. jobs, by Francois Martineau, Areva NP. Industry innovation articles include: MSL Acoustic source load reduction, by Amirmore » Shahkarami, Exelon Nuclear; Dual Methodology NDE of CRDM nozzles, by Michael Stark, Dominion Nuclear; and Electronic circuit board testing, by James Amundsen, FirstEnergy Nuclear Operating Company. The plant profile article is titled The future is now, by Julia Milstead, Progress Energy Service Company, LLC.« less

  3. Interamerican networks for physics education: some issues and comments

    NASA Astrophysics Data System (ADS)

    Halpern, Teodoro

    1988-10-01

    This paper provides comments about some critical and fundamental issues relevant to the creation of successful interamerican Networks for Physics Education, stressing the need for: Establishing the underlying educational goals for the proposed projects. Clear communication of these goals to interested constituencies and the public at large. Forceful image development to obtain wide-based funding. The interdependence of individuals and institutions in the networks. Closing the developed-vs.-underdeveloped schism. Sucess in this endeavour will eliminate one of the main reasons for failure of a ``cooperative'' project. This paper also provides examples of succesful interamerican Networks and some of the underlying for their successes.

  4. Targeting targeted agents: open issues for clinical trial design.

    PubMed

    Bria, Emilio; Di Maio, Massimo; Carlini, Paolo; Cuppone, Federica; Giannarelli, Diana; Cognetti, Francesco; Milella, Michele

    2009-05-22

    Molecularly targeted agents for the treatment of solid tumors had entered the market in the last 5 years, with a great impact upon both the scientific community and the society. Many randomized phase III trials conducted in recent years with new targeted agents, despite previous data coming from preclinical research and from phase II trials were often promising, have produced disappointingly negative results. Some other trials have actually met their primary endpoint, demonstrating a statistically significant result favouring the experimental treatment. Unfortunately, with a few relevant exceptions, this advantage is often small, if not negligible, in absolute terms. The difference between statistical significance and clinical relevance should always be considered when translating clinical trials' results in the practice. The reason why this 'revolution' did not significantly impact on cancer treatment to displace chemotherapy from the patient' bedside is in part due to complicated, and in many cases, unknown, mechanisms of action of such drugs; indeed, the traditional way the clinical investigators were used to test the efficacy of 'older' chemotherapeutics, has become 'out of date' from the methodological perspective. As these drugs should be theoretically tailored upon featured bio-markers expressed by the patients, the clinical trial design should follow new rules based upon stronger hypotheses than those developed so far. Indeed, the early phases of basic and clinical drug development are crucial in the correct process which is able to correctly identify the target (when present). Targeted trial designs can result in easier studies, with less, better selected, and supported by stronger proofs of response evidences, patients, in order to not waste time and resources.

  5. Impact of Visa Issues on an International Physics Graduate Student in the U.S.

    NASA Astrophysics Data System (ADS)

    Keivani, Azadeh

    2011-03-01

    More than 35 percent of the physics graduate students in the US are temporary visa holders. Many of these students work in large international collaborations and must travel abroad for research and international conferences, sometimes more than once a year. In many cases, students have to reapply for their visas in order to return to the U.S., a process that can be time-consuming and costly. Furthermore, many international students cannot leave the U.S. even in the case of an emergency because a slow visa process may mean deferring for a semester or losing financial support. Thus visa issues affect not only the scholastic life of students but also their personal lives. Finding ways to resolve these issues could positively affect the quality of graduate research by eliminating these extra hurdles to the progress of international physics graduate students.

  6. Dynamical and Physical Properties of 65803 Didymos, the AIDA Mission Target

    NASA Astrophysics Data System (ADS)

    Campo Bagatin, A.; Richardson, D. C.; Tsiganis, K.; Cheng, A. F.; Michel, P.

    2017-09-01

    The near-Earth asteroid (NEA) 65803 Didymos is a binary system and is the target of the proposed Asteroid Impact & Deflection Assessment (AIDA) mission, which combines an orbiter (Asteroid Impact Mission, AIM, or the reduced-scope AIM Deflection Demonstration, AIM-D2) [1, 2] and a kinetic impactor experiment (Double Asteroid Redirection Test, DART) planned to impact the secondary of the Didymos binary system in October, 2022 [3]. The Dynamical and Physical Properties of Didymos Working Group supports the AIDA mission by addressing questions related to understanding the dynamical state of the system and inferring the physical properties of the components

  7. Actinide targets for fundamental research in nuclear physics

    NASA Astrophysics Data System (ADS)

    Eberhardt, K.; Düllmann, Ch. E.; Haas, R.; Mokry, Ch.; Runke, J.; Thörle-Pospiech, P.; Trautmann, N.

    2018-05-01

    Thin actinide layers deposited on various substrates are widely used as calibration sources in nuclear spectroscopy. Other applications include fundamental research in nuclear chemistry and -physics, e.g., the chemical and physical properties of super-heavy elements (SHE, Z > 103) or nuclear reaction studies with heavy ions. For the design of future nuclear reactors like fast-fission reactors and accelerator-driven systems for transmutation of nuclear waste, precise data for neutron absorption as well as neutron-induced fission cross section data for 242Pu with neutrons of different energies are of particular importance, requiring suitable Pu-targets. Another application includes studies of nuclear transitions in 229Th harvested as α-decay recoil product from a thin layer of its 233U precursor. For this, a thin and very smooth layer of 233U is used. We report here on the production of actinide layers mostly obtained by Molecular Plating (MP). MP is currently the only fabrication method in cases where the desired actinide material is available only in very limited amounts or possesses a high specific activity. Here, deposition is performed from organic solution applying a current density of 1-2 mA/cm2. Under these conditions target thicknesses of 500-1000 μg/cm2 are possible applying a single deposition step with deposition yields approaching 100 %. For yield determination α-particle spectroscopy, γ-spectroscopy and Neutron Activation Analysis is routinely used. Layer homogeneity is checked with Radiographic Imaging. As an alternative technique to MP the production of thin lanthanide and actinide layers by the so-called "Drop on Demand"-technique applied e.g., in ink-jet printing is currently under investigation.

  8. Optimal Target Stars in the Search for Life

    NASA Astrophysics Data System (ADS)

    Lingam, Manasvi; Loeb, Abraham

    2018-04-01

    The selection of optimal targets in the search for life represents a highly important strategic issue. In this Letter, we evaluate the benefits of searching for life around a potentially habitable planet orbiting a star of arbitrary mass relative to a similar planet around a Sun-like star. If recent physical arguments implying that the habitability of planets orbiting low-mass stars is selectively suppressed are correct, we find that planets around solar-type stars may represent the optimal targets.

  9. Inclusion of Medical-Legal Issues in Entry-Level Occupational and Physical Therapy Curricula.

    ERIC Educational Resources Information Center

    Ekelman, Beth A.; Goodman, Glenn; Dal Bello-Haas, Vanina

    2000-01-01

    Directors of 47 occupational therapy (OT) and 65 physical therapy (PT) accredited entry-level programs responded to a survey by indicating their support for inclusion of medical-legal issues in the curriculum. Only 40% of OT and 52% of PT directors believed lawyers should deliver instruction; most felt their faculty were qualified to teach these…

  10. Teaching about Ethics through Socioscientific Issues in Physics and Chemistry: Teacher Candidates' Beliefs

    ERIC Educational Resources Information Center

    Barrett, Sarah Elizabeth; Nieswandt, Martina

    2010-01-01

    The purpose of this qualitative study was to identify and explain the origins of physics and chemistry teacher candidates' beliefs about teaching about ethics through socioscientific issues (SSI). This study utilized a series of in-depth interviews, while the participants (n = 12) were enrolled in a 9-month teacher education program at an urban…

  11. Targeting as a Mode of Science Communication: Principles, Issues and a Practical Example

    NASA Astrophysics Data System (ADS)

    Holland, G. J.; Vigh, J. L.

    2011-12-01

    Today's media landscape contains a rich and diverse range of communications opportunities. New media, such as the internet, blogosphere and social networks, are complementing, supplementing and also replacing the traditional mass media communications through print, radio and television. This diversification certainly contains pitfalls and difficulties as has been demonstrated in the Climategate affair. But there are also real opportunities for utilizing the diversity to provide targeted science communications that are framed in the context of the specific group of interest. That such targeting of audience attitudes and beliefs is an important key to effective science communications has been demonstrated by, for example, Leiserowitz, Maibach et al (2009). This approach does require an understanding of the audience and a careful framing of the message in terms familiar to the targeted group. Here many factors come into play, including: including immediacy, economics, culture, community leaders, emotional framing, and ideological filters. In this talk we shall elaborate on the principles, issues and opportunities. A practical example of working with the religious community on communicating the science of climate change will also be presented. This will include the approach adopted, progress to date and the lessons learnt.

  12. EDITORIAL: Special issue containing papers presented at the 12th International Workshop on H-mode Physics and Transport Barriers Special issue containing papers presented at the 12th International Workshop on H-mode Physics and Transport Barriers

    NASA Astrophysics Data System (ADS)

    Hahm, T. S.

    2010-06-01

    The 12th International Workshop on H-mode Physics and Transport Barriers was held at the Princeton Plasma Physics Laboratory, Princeton, New Jersey, USA between September 30 and October 2, 2009. This meeting was the continuation of a series of previous meetings which was initiated in 1987 and has been held bi-annually since then. Following the recent tradition at the last few meetings, the program was sub- divided into six sessions. At each session, an overview talk was presented, followed by two or three shorter oral presentations which supplemented the coverage of important issues. These talks were followed by discussion periods and poster sessions of contributed papers. The sessions were: Physics of Transition to/from Enhanced Confinement Regimes, Pedestal and Edge Localized Mode Dynamics, Plasma Rotation and Momentum Transport, Role of 3D Physics in Transport Barriers, Transport Barriers: Theory and Simulations and High Priority ITER Issues on Transport Barriers. The diversity of the 90 registered participants was remarkable, with 22 different nationalities. US participants were in the majority (36), followed by Japan (14), South Korea (7), and China (6). This special issue of Nuclear Fusion consists of a cluster of 18 accepted papers from submitted manuscripts based on overview talks and poster presentations. The paper selection procedure followed the guidelines of Nuclear Fusion which are essentially the same as for regular articles with an additional requirement on timeliness of submission, review and revision. One overview paper and five contributed papers report on the H-mode pedestal related results which reflect the importance of this issue concerning the successful operation of ITER. Four papers address the rotation and momentum transport which play a crucial role in transport barrier physics. The transport barrier transition condition is the main focus of other four papers. Finally, four additional papers are devoted to the behaviour and control of

  13. Effects of major parameters of nanoparticles on their physical and chemical properties and recent application of nanodrug delivery system in targeted chemotherapy.

    PubMed

    Zhang, Jing; Tang, Hua; Liu, Zefa; Chen, Baoan

    2017-01-01

    Chemotherapy is still one of the main cancer therapy treatments, but the curative effect of chemotherapy is relatively low, as such the development of a new cancer treatment is highly desirable. The gradual maturation of nanotechnology provides an innovative perspective not only for cancer therapy but also for many other applications. There are a diverse variety of nanoparticles available, and choosing the appropriate carriers according to the demand is the key issue. The performance of nanoparticles is affected by many parameters, mainly size, shape, surface charge, and toxicity. Using nanoparticles as the carriers to realize passive targeting and active targeting can improve the efficacy of chemotherapy drugs significantly, reduce the mortality rate of cancer patients, and improve the quality of life of patients. In recent years, there has been extensive research on nanocarriers. In this review, the effects of several major parameters of nanoparticles on their physical and chemical properties are reviewed, and then the recent progress in the application of several commonly used nanoparticles is presented.

  14. Accelerometer-based measures in physical activity surveillance: current practices and issues.

    PubMed

    Pedišić, Željko; Bauman, Adrian

    2015-02-01

    Self-reports of physical activity (PA) have been the mainstay of measurement in most non-communicable disease (NCD) surveillance systems. To these, other measures are added to summate to a comprehensive PA surveillance system. Recently, some national NCD surveillance systems have started using accelerometers as a measure of PA. The purpose of this paper was specifically to appraise the suitability and role of accelerometers for population-level PA surveillance. A thorough literature search was conducted to examine aspects of the generalisability, reliability, validity, comprehensiveness and between-study comparability of accelerometer estimates, and to gauge the simplicity, cost-effectiveness, adaptability and sustainability of their use in NCD surveillance. Accelerometer data collected in PA surveillance systems may not provide estimates that are generalisable to the target population. Accelerometer-based estimates have adequate reliability for PA surveillance, but there are still several issues associated with their validity. Accelerometer-based prevalence estimates are largely dependent on the investigators' choice of intensity cut-off points. Maintaining standardised accelerometer data collections in long-term PA surveillance systems is difficult, which may cause discontinuity in time-trend data. The use of accelerometers does not necessarily produce useful between-study and international comparisons due to lack of standardisation of data collection and processing methods. To conclude, it appears that accelerometers still have limitations regarding generalisability, validity, comprehensiveness, simplicity, affordability, adaptability, between-study comparability and sustainability. Therefore, given the current evidence, it seems that the widespread adoption of accelerometers specifically for large-scale PA surveillance systems may be premature. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence

  15. Pilot study of a targeted dance class for physical rehabilitation in children with cerebral palsy.

    PubMed

    López-Ortiz, Citlali; Egan, Tara; Gaebler-Spira, Deborah J

    2016-01-01

    This pilot study evaluates the effects of a targeted dance class utilizing classical ballet principles for rehabilitation of children with cerebral palsy on balance and upper extremity control. Twelve children with cerebral palsy (ages 7-15 years) with Gross Motor Function Classification scores II-IV participated in this study and were assigned to either a control group or targeted dance class group. Targeted dance class group participated in 1-h classes three times per week in a 4-week period. The Pediatric Balance Scale and the Quality of Upper Extremity Skills Test were administered before, after, and 1 month after the targeted dance class. Improvements in the Pediatric Balance Scale were present in the targeted dance class group in before versus after and before versus 1 month follow-up comparisons (p-value = 0.0088 and p-value = 0.019, respectively). The Pediatric Balance Scale changes were not significant in the control group. The Quality of Upper Extremity Skills Test did not reach statistical differences in either group. Classical ballet as an art form involves physical training, musical accompaniment, social interactions, and emotional expression that could serve as adjunct to traditional physical therapy. This pilot study demonstrated improvements in balance control. A larger study with a more homogeneous sample is warranted.

  16. Physical Activity in Vietnam: Estimates and Measurement Issues.

    PubMed

    Bui, Tan Van; Blizzard, Christopher Leigh; Luong, Khue Ngoc; Truong, Ngoc Le Van; Tran, Bao Quoc; Otahal, Petr; Srikanth, Velandai; Nelson, Mark Raymond; Au, Thuy Bich; Ha, Son Thai; Phung, Hai Ngoc; Tran, Mai Hoang; Callisaya, Michele; Gall, Seana

    2015-01-01

    Our aims were to provide the first national estimates of physical activity (PA) for Vietnam, and to investigate issues affecting their accuracy. Measurements were made using the Global Physical Activity Questionnaire (GPAQ) on a nationally-representative sample of 14706 participants (46.5% males, response 64.1%) aged 25-64 years selected by multi-stage stratified cluster sampling. Approximately 20% of Vietnamese people had no measureable PA during a typical week, but 72.9% (men) and 69.1% (women) met WHO recommendations for PA by adults for their age. On average, 52.0 (men) and 28.0 (women) Metabolic Equivalent Task (MET)-hours/week (largely from work activities) were reported. Work and total PA were higher in rural areas and varied by season. Less than 2% of respondents provided incomplete information, but an additional one-in-six provided unrealistically high values of PA. Those responsible for reporting errors included persons from rural areas and all those with unstable work patterns. Box-Cox transformation (with an appropriate constant added) was the most successful method of reducing the influence of large values, but energy-scaled values were most strongly associated with pathophysiological outcomes. Around seven-in-ten Vietnamese people aged 25-64 years met WHO recommendations for total PA, which was mainly from work activities and higher in rural areas. Nearly all respondents were able to report their activity using the GPAQ, but with some exaggerated values and seasonal variation in reporting. Data transformation provided plausible summary values, but energy-scaling fared best in association analyses.

  17. Physical Activity in Vietnam: Estimates and Measurement Issues

    PubMed Central

    Bui, Tan Van; Blizzard, Christopher Leigh; Luong, Khue Ngoc; Truong, Ngoc Le Van; Tran, Bao Quoc; Otahal, Petr; Srikanth, Velandai; Nelson, Mark Raymond; Au, Thuy Bich; Ha, Son Thai; Phung, Hai Ngoc; Tran, Mai Hoang; Callisaya, Michele; Gall, Seana

    2015-01-01

    Introduction Our aims were to provide the first national estimates of physical activity (PA) for Vietnam, and to investigate issues affecting their accuracy. Methods Measurements were made using the Global Physical Activity Questionnaire (GPAQ) on a nationally-representative sample of 14706 participants (46.5% males, response 64.1%) aged 25−64 years selected by multi-stage stratified cluster sampling. Results Approximately 20% of Vietnamese people had no measureable PA during a typical week, but 72.9% (men) and 69.1% (women) met WHO recommendations for PA by adults for their age. On average, 52.0 (men) and 28.0 (women) Metabolic Equivalent Task (MET)-hours/week (largely from work activities) were reported. Work and total PA were higher in rural areas and varied by season. Less than 2% of respondents provided incomplete information, but an additional one-in-six provided unrealistically high values of PA. Those responsible for reporting errors included persons from rural areas and all those with unstable work patterns. Box-Cox transformation (with an appropriate constant added) was the most successful method of reducing the influence of large values, but energy-scaled values were most strongly associated with pathophysiological outcomes. Conclusions Around seven-in-ten Vietnamese people aged 25–64 years met WHO recommendations for total PA, which was mainly from work activities and higher in rural areas. Nearly all respondents were able to report their activity using the GPAQ, but with some exaggerated values and seasonal variation in reporting. Data transformation provided plausible summary values, but energy-scaling fared best in association analyses. PMID:26485044

  18. Ethical Issues for Public Health Approaches to Obesity.

    PubMed

    Azevedo, Suzanna M; Vartanian, Lenny R

    2015-09-01

    Obesity is a major public health concern worldwide. Because individual-level interventions have been unsuccessful at curbing obesity rates, there is an emphasis on public health approaches. In addition to testing the effectiveness of any public health interventions, it is important to consider the ethical implications of these interventions in order to protect the public's rights and promote overall well-being. In this paper, we review public health approaches to obesity in three broad domains (changes to the socio-communicative environment, changes to the economic environment, and changes to the physical environment/access) and consider the potential ethical issues that arise in each of those domains. We suggest that interventions that target the physical environment/access (making it easier for people to engage in healthy behaviors), that target the entire population (rather than just individuals with obesity), and that focus on health behaviors (rather than on weight) have the least potential for ethical concerns.

  19. Issues in Space Physics in Need of Reconnection with Laboratory Physics

    NASA Astrophysics Data System (ADS)

    Coppi, B.

    2017-10-01

    Predicted space observations, such as the ``foot'' in front of collisionless shocks or the occurrence of magnetic reconnection in the Earth`s magnetotail leading to auroral substorms, have highlighted the fruitful connection of laboratory and space plasma physics. The emergence of high energy astrophysics has then benefitted by the contribution of experiments devised for fusion research to the understanding of issues such as that of angular momentum transport processes that have a key role in allowing accretion of matter on a central object (e.g. black hole). The theory proposed for the occurrence of spontaneous rotation in toroidal plasmas was suggested by that developed for accretion. The particle density values, =1015 cm-3 that are estimated to be those of plasmas surrounding known galactic black holes have in fact been produced by the Alcator and other machines. Collective modes excited in the presence of high energy particle populations in laboratory plasmas (e.g. when the ``slide away'' regime has been produced) have found successful applications in space. Magnetic reconnection theory developments and the mode particle resonances associated with them have led to envision new processes for novel high energy particle acceleration. Sponsored in part by the U.S. DoE.

  20. Clinician-targeted intervention and patient-reported counseling on physical activity.

    PubMed

    Carroll, Jennifer K; Winters, Paul C; Sanders, Mechelle R; Decker, Francesca; Ngo, Thanh; Sciamanna, Christopher N

    2014-05-29

    Limited time and lack of knowledge are barriers to physical activity counseling in primary care. The objective of this study was to examine the effectiveness of a clinician-targeted intervention that used the 5As (Ask, Advise, Agree, Assist, Arrange) approach to physical activity counseling in a medically underserved patient population. Family medicine clinicians at 2 community health centers were randomized to Group 1 or Group 2 intervention. Both clinician groups participated in 4 training sessions on the 5As for physical activity counseling; Group 2 training took place 8 months after Group 1 training. Both groups were trained to refer patients to a community exercise program. We used a pre-post analysis to evaluate the effectiveness of the intervention on clinician use of 5As. Eligible patients (n = 319) rated their clinicians' counseling skills by using a modified Physical Activity Exit Interview (PAEI) survey. Clinicians (n = 10) self-assessed their use of the 5As through a survey and interviews. Both patient and clinician groups had similar sociodemographic characteristics. The PAEI score for both groups combined increased from 6.9 to 8.6 (on a scale of 0-15) from baseline to immediately postintervention (P = .01) and was 8.2 (P = .09) at 6-month follow-up; most of the improvement in PAEI score was due to increased use of 5As skills by Group 2 clinicians. Group 1 reported difficulty with problem solving, whereas Group 2 reported ease of referral to the community exercise program. A clinician training intervention showed mixed results for 5As physical activity counseling.

  1. The face of AIDS: Effects of physical attractiveness and target gender on inferred mode of HIV infection.

    PubMed

    Boehm, L; Wambaugh, M; Riney, T; Kunzelman, C

    1996-04-01

    We examined the effects of physical attractiveness on the assumed mode of HIV acquisition. 176 students read a description of an HIV-positive target whose photograph was placed above the description. A 2 (target gender) by 2 (attractive or unattractive target) factorial design was used. Unattractive targets were perceived as more likely to have acquired HIV through homosexual relationships. Further, men were perceived as more likely than women to have acquired HIV homosexually. Attractiveness did not bias health-care allocations regarding the infected target.

  2. Physics perspectives with AFTER@LHC (A Fixed Target ExpeRiment at LHC)

    NASA Astrophysics Data System (ADS)

    Massacrier, L.; Anselmino, M.; Arnaldi, R.; Brodsky, S. J.; Chambert, V.; Da Silva, C.; Didelez, J. P.; Echevarria, M. G.; Ferreiro, E. G.; Fleuret, F.; Gao, Y.; Genolini, B.; Hadjidakis, C.; Hřivnáčová, I.; Kikola, D.; Klein, A.; Kurepin, A.; Kusina, A.; Lansberg, J. P.; Lorcé, C.; Lyonnet, F.; Martinez, G.; Nass, A.; Pisano, C.; Robbe, P.; Schienbein, I.; Schlegel, M.; Scomparin, E.; Seixas, J.; Shao, H. S.; Signori, A.; Steffens, E.; Szymanowski, L.; Topilskaya, N.; Trzeciak, B.; Uggerhøj, U. I.; Uras, A.; Ulrich, R.; Wagner, J.; Yamanaka, N.; Yang, Z.

    2018-02-01

    AFTER@LHC is an ambitious fixed-target project in order to address open questions in the domain of proton and neutron spins, Quark Gluon Plasma and high-x physics, at the highest energy ever reached in the fixed-target mode. Indeed, thanks to the highly energetic 7 TeV proton and 2.76 A.TeV lead LHC beams, center-of-mass energies as large as = 115 GeV in pp/pA and = 72 GeV in AA can be reached, corresponding to an uncharted energy domain between SPS and RHIC. We report two main ways of performing fixed-target collisions at the LHC, both allowing for the usage of one of the existing LHC experiments. In these proceedings, after discussing the projected luminosities considered for one year of data taking at the LHC, we will present a selection of projections for light and heavy-flavour production.

  3. Pilot study of a targeted dance class for physical rehabilitation in children with cerebral palsy

    PubMed Central

    López-Ortiz, Citlali; Egan, Tara; Gaebler-Spira, Deborah J

    2016-01-01

    Introduction: This pilot study evaluates the effects of a targeted dance class utilizing classical ballet principles for rehabilitation of children with cerebral palsy on balance and upper extremity control. Methods: Twelve children with cerebral palsy (ages 7–15 years) with Gross Motor Function Classification scores II–IV participated in this study and were assigned to either a control group or targeted dance class group. Targeted dance class group participated in 1-h classes three times per week in a 4-week period. The Pediatric Balance Scale and the Quality of Upper Extremity Skills Test were administered before, after, and 1 month after the targeted dance class. Results: Improvements in the Pediatric Balance Scale were present in the targeted dance class group in before versus after and before versus 1 month follow-up comparisons (p-value = 0.0088 and p-value = 0.019, respectively). The Pediatric Balance Scale changes were not significant in the control group. The Quality of Upper Extremity Skills Test did not reach statistical differences in either group. Conclusion: Classical ballet as an art form involves physical training, musical accompaniment, social interactions, and emotional expression that could serve as adjunct to traditional physical therapy. This pilot study demonstrated improvements in balance control. A larger study with a more homogeneous sample is warranted. PMID:27721977

  4. Relationship between physical activity level and psychosocial and socioeconomic factors and issues in children and adolescents with asthma: a scoping review.

    PubMed

    Westergren, Thomas; Berntsen, Sveinung; Ludvigsen, Mette Spliid; Aagaard, Hanne; Hall, Elisabeth O C; Ommundsen, Yngvar; Uhrenfeldt, Lisbeth; Fegran, Liv

    2017-08-01

    Asthma is a heterogeneous chronic airway disease which may reduce capability for physical activity. In healthy peers, physical activity is influenced by psychosocial and socioeconomic factors. Knowledge about the role of these factors has not been mapped in children and adolescents with asthma. The main objective of this scoping review was to identify psychosocial and socioeconomic factors associated with physical activity level in children and adolescents with asthma in the literature. The specific objectives were to map the instruments used to measure these factors, report on the construction and validation of these instruments, map psychosocial and socioeconomic issues related to physical activity level reported in qualitative studies, and identify gaps in knowledge about the relationship between psychosocial and socioeconomic factors and physical activity level in children and adolescents with asthma. Children and adolescents with asthma aged six to 18 years. Psychosocial and socioeconomic factors related to physical activity level and participation. All physical activity contexts. Quantitative and qualitative primary studies in English, with no date limit. The databases searched included nine major databases for health and sports science, and five databases for unpublished studies. After screening and identification of studies, the reference lists of all identified reports were searched, and forward citation searches were conducted using four databases. The following data were extracted: (a) relevant study characteristics and assessment of physical activity level, (b) instruments used to assess psychosocial and socioeconomic factors, (c) association between physical activity level and these factors, (d) construction and validation of instruments, and (e) psychosocial and socioeconomic issues related to physical activity participation. Twenty-one quantitative and 13 qualitative studies were included. In cross-sectional studies, enjoyment, physical self

  5. Clinician-Targeted Intervention and Patient-Reported Counseling on Physical Activity

    PubMed Central

    Winters, Paul C.; Sanders, Mechelle R.; Decker, Francesca; Ngo, Thanh; Sciamanna, Christopher N.

    2014-01-01

    Introduction Limited time and lack of knowledge are barriers to physical activity counseling in primary care. The objective of this study was to examine the effectiveness of a clinician-targeted intervention that used the 5As (Ask, Advise, Agree, Assist, Arrange) approach to physical activity counseling in a medically underserved patient population. Methods Family medicine clinicians at 2 community health centers were randomized to Group 1 or Group 2 intervention. Both clinician groups participated in 4 training sessions on the 5As for physical activity counseling; Group 2 training took place 8 months after Group 1 training. Both groups were trained to refer patients to a community exercise program. We used a pre–post analysis to evaluate the effectiveness of the intervention on clinician use of 5As. Eligible patients (n = 319) rated their clinicians’ counseling skills by using a modified Physical Activity Exit Interview (PAEI) survey. Clinicians (n = 10) self-assessed their use of the 5As through a survey and interviews. Results Both patient and clinician groups had similar sociodemographic characteristics. The PAEI score for both groups combined increased from 6.9 to 8.6 (on a scale of 0–15) from baseline to immediately postintervention (P = .01) and was 8.2 (P = .09) at 6-month follow-up; most of the improvement in PAEI score was due to increased use of 5As skills by Group 2 clinicians. Group 1 reported difficulty with problem solving, whereas Group 2 reported ease of referral to the community exercise program. Conclusion A clinician training intervention showed mixed results for 5As physical activity counseling. PMID:24874781

  6. Physical activity and sedentary behaviours in youth: issues and controversies.

    PubMed

    Biddle, Stuart J; Gorely, Trish; Marshall, Simon J; Murdey, Ian; Cameron, Noel

    2004-01-01

    There is growing concern over the effects of sedentary lifestyles on the health of young people. Recent rapid increases in juvenile obesity have received a great deal of attention in the scientific and popular press and have been attributed partly to television viewing, computer games and other sedentary behaviours. These are thought to compete with physical activity. There is a 'moral panic' concerning the 'couch kids' culture in modern western society. Project STIL (Sedentary Teenagers and Inactive Lifestyles) at Loughborough University is investigating 'what young people do' and focuses on active and inactive pursuits chosen in their leisure time. The following issues are addressed in this paper with specific reference to young people: how do we define 'sedentary behaviour' and do key sedentary behaviours displace physical activity? Are key sedentary behaviours obesogenic? What are the secular trends for children and youth for TV viewing? Our results for young people suggest that: 1. TV viewing and video-game playing are largely uncorrelated with physical activity, suggesting that there is time for both 2. meta-analytic findings show that body fatness is not related in any clinically meaningful way with key sedentary behaviours 3. although more children and youth have greater access to TVs than in previous generations, the amount of TV watched per head has not changed for 40 years. Preliminary findings from Project STIL suggest that inactivity is more complex that we sometimes think. Indeed, measures of 'couch potato-ism', such as TV viewing, may be inappropriate markers of inactivity.

  7. Effects of major parameters of nanoparticles on their physical and chemical properties and recent application of nanodrug delivery system in targeted chemotherapy

    PubMed Central

    Liu, Zefa; Chen, Baoan

    2017-01-01

    Chemotherapy is still one of the main cancer therapy treatments, but the curative effect of chemotherapy is relatively low, as such the development of a new cancer treatment is highly desirable. The gradual maturation of nanotechnology provides an innovative perspective not only for cancer therapy but also for many other applications. There are a diverse variety of nanoparticles available, and choosing the appropriate carriers according to the demand is the key issue. The performance of nanoparticles is affected by many parameters, mainly size, shape, surface charge, and toxicity. Using nanoparticles as the carriers to realize passive targeting and active targeting can improve the efficacy of chemotherapy drugs significantly, reduce the mortality rate of cancer patients, and improve the quality of life of patients. In recent years, there has been extensive research on nanocarriers. In this review, the effects of several major parameters of nanoparticles on their physical and chemical properties are reviewed, and then the recent progress in the application of several commonly used nanoparticles is presented. PMID:29238188

  8. A high density field reversed configuration (FRC) target for magnetized target fusion: First internal profile measurements of a high density FRC

    NASA Astrophysics Data System (ADS)

    Intrator, T.; Zhang, S. Y.; Degnan, J. H.; Furno, I.; Grabowski, C.; Hsu, S. C.; Ruden, E. L.; Sanchez, P. G.; Taccetti, J. M.; Tuszewski, M.; Waganaar, W. J.; Wurden, G. A.

    2004-05-01

    Magnetized target fusion (MTF) is a potentially low cost path to fusion, intermediate in plasma regime between magnetic and inertial fusion energy. It requires compression of a magnetized target plasma and consequent heating to fusion relevant conditions inside a converging flux conserver. To demonstrate the physics basis for MTF, a field reversed configuration (FRC) target plasma has been chosen that will ultimately be compressed within an imploding metal liner. The required FRC will need large density, and this regime is being explored by the FRX-L (FRC-Liner) experiment. All theta pinch formed FRCs have some shock heating during formation, but FRX-L depends further on large ohmic heating from magnetic flux annihilation to heat the high density (2-5×1022m-3), plasma to a temperature of Te+Ti≈500 eV. At the field null, anomalous resistivity is typically invoked to characterize the resistive like flux dissipation process. The first resistivity estimate for a high density collisional FRC is shown here. The flux dissipation process is both a key issue for MTF and an important underlying physics question.

  9. Issues with Strong Compression of Plasma Target by Stabilized Imploding Liner

    NASA Astrophysics Data System (ADS)

    Turchi, Peter; Frese, Sherry; Frese, Michael

    2017-10-01

    Strong compression (10:1 in radius) of an FRC by imploding liquid metal liners, stabilized against Rayleigh-Taylor modes, using different scalings for loss based on Bohm vs 100X classical diffusion rates, predict useful compressions with implosion times half the initial energy lifetime. The elongation (length-to-diameter ratio) near peak compression needed to satisfy empirical stability criterion and also retain alpha-particles is about ten. The present paper extends these considerations to issues of the initial FRC, including stability conditions (S*/E) and allowable angular speeds. Furthermore, efficient recovery of the implosion energy and alpha-particle work, in order to reduce the necessary nuclear gain for an economical power reactor, is seen as an important element of the stabilized liner implosion concept for fusion. We describe recent progress in design and construction of the high energy-density prototype of a Stabilized Liner Compressor (SLC) leading to repetitive laboratory experiments to develop the plasma target. Supported by ARPA-E ALPHA Program.

  10. Familiar trajectories facilitate the interpretation of physical forces when intercepting a moving target.

    PubMed

    Mijatović, Antonija; La Scaleia, Barbara; Mercuri, Nicola; Lacquaniti, Francesco; Zago, Myrka

    2014-12-01

    Familiarity with the visual environment affects our expectations about the objects in a scene, aiding in recognition and interaction. Here we tested whether the familiarity with the specific trajectory followed by a moving target facilitates the interpretation of the effects of underlying physical forces. Participants intercepted a target sliding down either an inclined plane or a tautochrone. Gravity accelerated the target by the same amount in both cases, but the inclined plane represented a familiar trajectory whereas the tautochrone was unfamiliar to the participants. In separate sessions, the gravity field was consistent with either natural gravity or artificial reversed gravity. Target motion was occluded from view over the last segment. We found that the responses in the session with unnatural forces were systematically delayed relative to those with natural forces, but only for the inclined plane. The time shift is consistent with a bias for natural gravity, in so far as it reflects an a priori expectation that a target not affected by natural forces will arrive later than one accelerated downwards by gravity. Instead, we did not find any significant time shift with unnatural forces in the case of the tautochrone. We argue that interception of a moving target relies on the integration of the high-level cue of trajectory familiarity with low-level cues related to target kinematics.

  11. The Physics of Advanced High-Gain Targets for Inertial Fusion Energy

    NASA Astrophysics Data System (ADS)

    Perkins, L. John

    2010-11-01

    In ca. 2011-2012, the National Ignition Facility is poised to demonstrate fusion ignition and gain in the laboratory for the first time. This key milestone in the development of inertial confinement fusion (ICF) can be expected to engender interest in the development of inertial fusion energy (IFE) and expanded efforts on a number of advanced targets that may achieve high fusion energy gain at lower driver energies. In this tutorial talk, we will discuss the physics underlying ICF ignition and thermonuclear burn, examine the requirements for high gain, and outline candidate R&D programs that will be required to assess the performance of these target concepts under various driver systems including lasers, heavy-ions and pulsed power. Such target concepts include those operating by fast ignition, shock ignition, impact ignition, dual-density, magnetically-insulated, one- and two-sided drive, etc., some of which may have potential to burn advanced, non-DT fusion fuels. We will then delineate the role of such targets in their application to the production of high average fusion power. Here, systems studies of IFE economics suggest that we should strive for target fusion gains of around 100 at drive energies of 1MJ, together with corresponding rep-rates of up to 10Hz and driver electrical efficiencies around 15%. In future years, there may be exciting opportunities to study such ``innovative confinement concepts'' with prospects of fielding them on facilities such as NIF to obtain high fusion energy gains on a single shot basis.

  12. Physical Education: Essential Issues

    ERIC Educational Resources Information Center

    Green, Ken, Ed.; Hardman, Ken, Ed.

    2005-01-01

    This book is aimed primarily at under and postgraduate students pursuing entire programmes or discrete courses and modules in the broad area of physical education and sport in schools. It consists of a collection of what is considered to be essential readings in the sense that they are contributions from eminent authors on a breadth of salient…

  13. CALL FOR PAPERS: Special issue on the random search problem: trends and perspectives

    NASA Astrophysics Data System (ADS)

    da Luz, Marcos G. E.; Grosberg, Alexander Y.; Raposo, Ernesto P.; Viswanathan, Gandhi M.

    2008-11-01

    This is a call for contributions to a special issue of Journal of Physics A: Mathematical and Theoretical dedicated to the subject of the random search problem. The motivation behind this special issue is to summarize in a single comprehensive publication, the main aspects (past and present), latest developments, different viewpoints and the directions being followed in this multidisciplinary field. We hope that such a special issue could become a particularly valuable reference for the broad scientific community working with the general random search problem. The Editorial Board has invited Marcos G E da Luz, Alexander Y Grosberg, Ernesto P Raposo and Gandhi M Viswanathan to serve as Guest Editors for the special issue. The general question of how to optimize the search for specific target objects in either continuous or discrete environments when the information available is limited is of significant importance in a broad range of fields. Representative examples include ecology (animal foraging, dispersion of populations), geology (oil recovery from mature reservoirs), information theory (automated researchers of registers in high-capacity database), molecular biology (proteins searching for their sites, e.g., on DNA ), etc. One reason underlying the richness of the random search problem relates to the `ignorance' of the locations of the randomly located `targets'. A statistical approach to the search problem can deal adequately with incomplete information and so stochastic strategies become advantageous. The general problem of how to search efficiently for randomly located target sites can thus be quantitatively described using the concepts and methods of statistical physics and stochastic processes. Scope Thus far, to the best of our knowledge, no recent textbook or review article in a physics journal has appeared on this topic. This makes a special issue with review and research articles attractive to those interested in acquiring a general introduction to the

  14. Promoting Physical Activity in Childhood Cancer Survivors: Targets for Intervention

    PubMed Central

    Montgomery, Michele; Oeffinger, Kevin C.; Leisenring, Wendy; Zeltzer, Lonnie; Whitton, John A.; Mertens, Ann C.; Hudson, Melissa M.; Robison, Leslie L.

    2009-01-01

    Purpose Although physical activity may modify the late effects of childhood cancer treatment, 20%-52% of adult survivors are sedentary. We sought to identify modifiable factors that influence survivors' participation in physical activity. Methods Structural equation modeling of data from the Childhood Cancer Survivors Study of adult survivors (current mean age, 30.98 years; mean years since diagnosis, 23.74; mean age at diagnosis, 9.25 years) diagnosed between 1970 and 1986. Results Forty percent of the variance in male survivors' recent participation vs. nonparticipation in physical activity was explained directly and/or indirectly by self-reported health fears (P=0.01), perceived primary-care physician (PCP) expertise (P=0.01), baseline exercise frequency (P=<0.001), education level (P=0.01), self-reported stamina (P=0.01), cancer-related pain (P=<0.001), fatigue (P=<0.001), age at diagnosis (P=0.01), cancer-related anxiety (P=<0.001), motivation (P=0.01), affect (P=0.01), and discussion of subsequent cancer risk with the PCP (P=<0.001) (N=256; X2=53.38, df=51, P=0.38, CFI=1.000, TLI=1.000, RMSEA=0.014,WRMR=0.76). Thirty-one percent of the variance in females' recent physical activity participation was explained directly and/or indirectly by self-reported stamina (P=<0.001), fatigue (P=0.01), baseline exercise frequency (P=0.01), cancer-related pain (P=<0.001), cancer-related anxiety (P=0.01), recency of visits with PCP (<0.001), quality of interaction with the PCP (P=0.01), and motivation (P=<0.001) (N=366; X2=67.52 df=55, P=0.12, CFI=0.98, TLI=0.98, RMSEA=0.025, WRMR=0.76). Conclusions Gender-tailored intervention strategies in which providers specifically target motivation, fear, and affect may support physical activity in childhood cancer survivors. PMID:19117349

  15. A physics-based solver to optimize the illumination of cylindrical targets in spherically distributed high power laser systems.

    PubMed

    Gourdain, P-A

    2017-05-01

    In recent years, our understanding of high energy density plasmas has played an important role in improving inertial fusion confinement and in emerging new fields of physics, such as laboratory astrophysics. Every new idea required developing innovative experimental platforms at high power laser facilities, such as OMEGA or NIF. These facilities, designed to focus all their beams onto spherical targets or hohlraum windows, are now required to shine them on more complex targets. While the pointing on planar geometries is relatively straightforward, it becomes problematic for cylindrical targets or target with more complex geometries. This publication describes how the distribution of laser beams on a cylindrical target can be done simply by using a set of physical laws as a pointing procedure. The advantage of the method is threefold. First, it is straightforward, requiring no mathematical enterprise besides solving ordinary differential equations. Second, it will converge if a local optimum exists. Finally, it is computationally inexpensive. Experimental results show that this approach produces a geometrical beam distribution that yields cylindrically symmetric implosions.

  16. A physics-based solver to optimize the illumination of cylindrical targets in spherically distributed high power laser systems

    NASA Astrophysics Data System (ADS)

    Gourdain, P.-A.

    2017-05-01

    In recent years, our understanding of high energy density plasmas has played an important role in improving inertial fusion confinement and in emerging new fields of physics, such as laboratory astrophysics. Every new idea required developing innovative experimental platforms at high power laser facilities, such as OMEGA or NIF. These facilities, designed to focus all their beams onto spherical targets or hohlraum windows, are now required to shine them on more complex targets. While the pointing on planar geometries is relatively straightforward, it becomes problematic for cylindrical targets or target with more complex geometries. This publication describes how the distribution of laser beams on a cylindrical target can be done simply by using a set of physical laws as a pointing procedure. The advantage of the method is threefold. First, it is straightforward, requiring no mathematical enterprise besides solving ordinary differential equations. Second, it will converge if a local optimum exists. Finally, it is computationally inexpensive. Experimental results show that this approach produces a geometrical beam distribution that yields cylindrically symmetric implosions.

  17. Neurodegenerative diseases in the era of targeted therapeutics: how to handle a tangled issue.

    PubMed

    Tofaris, George K; Schapira, Anthony H V

    2015-05-01

    Neurodegenerative diseases are age-related and relentlessly progressive with increasing prevalence and no cure or lasting symptomatic therapy. The well-recognized prodromal phase in many forms of neurodegeneration suggests a prolonged period of neuronal compensated dysfunction prior to cell loss that may be amenable to therapeutic intervention. Although most efforts to date have been focused on misfolded toxic proteins, it is now clear that widespread changes in protein homeostasis occur early in these diseases and understanding this fundamental biology is key to the design of targeted therapies. What has emerged from molecular genetics and animal studies is a previously less appreciated association of neurodegenerative diseases with defects in the molecular regulation of protein trafficking between cellular organelles, especially the intricate network of endosomes, lysosomes, autophagosomes and mitochondria. Here we summarized the broader concepts that stemmed from this Special Issue on "Protein Clearance in Neurodegenerative diseases: from mechanisms to therapies". This article is part of a Special Issue entitled 'Neuronal Protein'. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. Targeted Employment Subsidies: Issues of Structure and Design.

    ERIC Educational Resources Information Center

    Bishop, John; Haveman, Robert

    Effects of variations in the structure of targeted employment subsidy programs on the attainment of program objectives are explored in this paper. First, the objectives that underlie targeted subsidy programs are outlined in relation to individual program characteristics and the economics of such programs are discussed. Then the wide range of…

  19. Ethical issues in exercise psychology.

    PubMed

    Pauline, Jeffrey S; Pauline, Gina A; Johnson, Scott R; Gamble, Kelly M

    2006-01-01

    Exercise psychology encompasses the disciplines of psychiatry, clinical and counseling psychology, health promotion, and the movement sciences. This emerging field involves diverse mental health issues, theories, and general information related to physical activity and exercise. Numerous research investigations across the past 20 years have shown both physical and psychological benefits from physical activity and exercise. Exercise psychology offers many opportunities for growth while positively influencing the mental and physical health of individuals, communities, and society. However, the exercise psychology literature has not addressed ethical issues or dilemmas faced by mental health professionals providing exercise psychology services. This initial discussion of ethical issues in exercise psychology is an important step in continuing to move the field forward. Specifically, this article will address the emergence of exercise psychology and current health behaviors and offer an overview of ethics and ethical issues, education/training and professional competency, cultural and ethnic diversity, multiple-role relationships and conflicts of interest, dependency issues, confidentiality and recording keeping, and advertisement and self-promotion.

  20. Perceptions of plagiarisers: The influence of target physical attractiveness, transgression severity, and sex on attributions of guilt and punishment.

    PubMed

    Swami, Viren; Arthey, Elizabeth; Furnham, Adrian

    2017-09-01

    The attractiveness-leniency effect (ALE) suggests that physically attractive targets are less likely to be perceived as guilty compared to less attractive targets. Here, we tested the ALE in relation to attributions of students who have committed plagiarism. British adults (N=165) were shown one of eight vignette-photograph pairings varying in target sex (female/male), physical attractiveness (high/low), and transgression severity (serious/minor), and provided attributions of guilt and severity of punishment. Analyses of variance revealed significant interactions between attractiveness and transgression severity for both dependent measures. Attractive targets were perceived as guiltier and deserving of more severe punishments in the serious transgression condition, but there was no significant difference between attractive and less attractive targets in the minor transgression condition. These results are discussed in terms of a reverse attribution bias, in which attractive individuals are judged more negatively when they fail to live up to higher standards of conduct. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Currency target-zone modeling: An interplay between physics and economics.

    PubMed

    Lera, Sandro Claudio; Sornette, Didier

    2015-12-01

    We study the performance of the euro-Swiss franc exchange rate in the extraordinary period from September 6, 2011 to January 15, 2015 when the Swiss National Bank enforced a minimum exchange rate of 1.20 Swiss francs per euro. Within the general framework built on geometric Brownian motions and based on the analogy between Brownian motion in finance and physics, the first-order effect of such a steric constraint would enter a priori in the form of a repulsive entropic force associated with the paths crossing the barrier that are forbidden. Nonparametric empirical estimates of drift and volatility show that the predicted first-order analogy between economics and physics is incorrect. The clue is to realize that the random-walk nature of financial prices results from the continuous anticipation of traders about future opportunities, whose aggregate actions translate into an approximate efficient market with almost no arbitrage opportunities. With the Swiss National Bank's stated commitment to enforce the barrier, traders' anticipation of this action leads to a vanishing drift together with a volatility of the exchange rate that depends on the distance to the barrier. This effect is described by Krugman's model [P. R. Krugman, Target zones and exchange rate dynamics, Q. J. Econ. 106, 669 (1991)]. We present direct quantitative empirical evidence that Krugman's theoretical model provides an accurate description of the euro-Swiss franc target zone. Motivated by the insights from the economic model, we revise the initial economics-physics analogy and show that, within the context of hindered diffusion, the two systems can be described with the same mathematics after all. Using a recently proposed extended analogy in terms of a colloidal Brownian particle embedded in a fluid of molecules associated with the underlying order book, we derive that, close to the restricting boundary, the dynamics of both systems is described by a stochastic differential equation with a very

  2. Currency target-zone modeling: An interplay between physics and economics

    NASA Astrophysics Data System (ADS)

    Lera, Sandro Claudio; Sornette, Didier

    2015-12-01

    We study the performance of the euro-Swiss franc exchange rate in the extraordinary period from September 6, 2011 to January 15, 2015 when the Swiss National Bank enforced a minimum exchange rate of 1.20 Swiss francs per euro. Within the general framework built on geometric Brownian motions and based on the analogy between Brownian motion in finance and physics, the first-order effect of such a steric constraint would enter a priori in the form of a repulsive entropic force associated with the paths crossing the barrier that are forbidden. Nonparametric empirical estimates of drift and volatility show that the predicted first-order analogy between economics and physics is incorrect. The clue is to realize that the random-walk nature of financial prices results from the continuous anticipation of traders about future opportunities, whose aggregate actions translate into an approximate efficient market with almost no arbitrage opportunities. With the Swiss National Bank's stated commitment to enforce the barrier, traders' anticipation of this action leads to a vanishing drift together with a volatility of the exchange rate that depends on the distance to the barrier. This effect is described by Krugman's model [P. R. Krugman, Target zones and exchange rate dynamics, Q. J. Econ. 106, 669 (1991), 10.2307/2937922]. We present direct quantitative empirical evidence that Krugman's theoretical model provides an accurate description of the euro-Swiss franc target zone. Motivated by the insights from the economic model, we revise the initial economics-physics analogy and show that, within the context of hindered diffusion, the two systems can be described with the same mathematics after all. Using a recently proposed extended analogy in terms of a colloidal Brownian particle embedded in a fluid of molecules associated with the underlying order book, we derive that, close to the restricting boundary, the dynamics of both systems is described by a stochastic differential

  3. Relations of Physical Activity and Stress Vulnerability in University Students

    ERIC Educational Resources Information Center

    Xu, Furong; Liu, Wenhao; Chepyator-Thomson, Jepkorir Rose; Schmidlein, Robert

    2018-01-01

    There are increased concerns about depression and anxiety among college students. Thus in need of actions to find proper intervention strategies to target this issue. The purpose of this study was to examine association between leisure-time physical activity and stress vulnerability among college students. A modified survey including physical…

  4. Messages for men: the efficacy of EPPM-based messages targeting men's physical activity.

    PubMed

    Hatchell, Alexandra C; Bassett-Gunter, Rebecca L; Clarke, Marie; Kimura, Stacey; Latimer-Cheung, Amy E

    2013-01-01

    The majority of men are insufficiently active. Men's tendencies to participate in risky behaviors and their inactivity likely contribute to their increased risk of morbidity and mortality. Physical activity decreases the risk of developing many chronic diseases and may be an optimal behavior to target in men's health interventions. However, educational resources promoting physical activity for men are lacking. To address this gap, we tested the efficacy of messages based upon the Extended Parallel Process Model (EPPM; Witte, 1992) to increase men's physical activity intentions and behaviors. Men who were not meeting physical activity guidelines (n = 611) were randomly assigned to read high or low efficacy physical activity messages paired with high or no health risk information. Participants read four brief messages on four consecutive days. Intentions were assessed at baseline and the first follow-up (Day 5). Manipulation check measures were assessed at Day 5. Behavior was assessed at baseline and the second follow-up (Day 14). Overall, the messages had small sized effects. A completer analysis revealed that although men's intentions to be active increased over the course of the study regardless of the messages they received, only men who received risk information significantly increased their physical activity. Men who received low efficacy and risk information were less likely to meet the physical activity guidelines at Day 14 than men who only received low efficacy information. From these results, we suggest preliminary recommendations for the development of physical activity messages for men and areas for future EPPM-based research. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  5. High energy density physics issues related to Future Circular Collider

    NASA Astrophysics Data System (ADS)

    Tahir, N. A.; Burkart, F.; Schmidt, R.; Shutov, A.; Wollmann, D.; Piriz, A. R.

    2017-07-01

    A design study for a post-Large Hadron Collider accelerator named, Future Circular Collider (FCC), is being carried out by the International Scientific Community. A complete design report is expected to be ready by spring 2018. The FCC will accelerate two counter rotating beams of 50 TeV protons in a tunnel having a length (circumference) of 100 km. Each beam will be comprised of 10 600 proton bunches, with each bunch having an intensity of 1011 protons. The bunch length is of 0.5 ns, and two neighboring bunches are separated by 25 ns. Although there is an option for 5 ns bunch separation as well, in the present studies, we consider the former case only. The total energy stored in each FCC beam is about 8.5 GJ, which is equivalent to the kinetic energy of Airbus 380 (560 t) flying at a speed of 850 km/h. Machine protection is a very important issue while operating with such powerful beams. It is important to have an estimate of the damage caused to the equipment and accelerator components due to the accidental release of a partial or total beam at a given point. For this purpose, we carried out numerical simulations of full impact of one FCC beam on an extended solid copper target. These simulations have been done employing an energy deposition code, FLUKA, and a two-dimensional hydrodynamic code, BIG2, iteratively. This study shows that although the static range of a single FCC proton and its shower is about 1.5 m in solid copper, the entire beam will penetrate around 350 m into the target. This substantial increase in the range is due to the hydrodynamic tunneling of the beam. Our calculations also show that a large part of the target will be converted into high energy density matter including warm dense matter and strongly coupled plasmas.

  6. Controversial Issues in Healthcare Policy: A Survey of Doctor of Physical Therapy Students in a Public University.

    PubMed

    Snyder, Drew D; Bennett, Teale K; Oller, Jeremy C; Ge, Weiqing

    2017-01-01

    The recently passed legislation and proposed policy changes governing the healthcare system have been met with extensive debate and controversy. The primary objective of the study was to determine the attitudes of Doctor of Physical Therapy (DPT) students towards some of these controversial issues. The secondary objective was to determine the demographic factors, including number of years in a physical therapy program, that contribute to their attitude formation. The research design was a cross-sectional non-experimental survey. Purposive sampling was used to recruit subjects in a public university. Subjects took the survey including nine Likert scale questions/statements on controversial issues inspired from legislative efforts and news media sources and one open-ended question. Of the 111 recruited, 106 students agreed to participate as subjects and completed the survey. Only 18.9% agreed or strongly agreed that the Patient Protection and Affordable Care Act is a positive solution for the healthcare system in America. Political affiliation, class level, and developmental environment were associated with a few questions/statements. DPT students in the sample had very diverse attitudes towards controversial issues in healthcare policy. Some of these attitudes revealed very different paradigms from the results found among medical students and the general public.

  7. Target population's requirements on a community-based intervention for stimulating physical activity in hard-to-reach physically disabled people: an interview study.

    PubMed

    Krops, Leonie A; Folkertsma, Nienke; Hols, Doortje H J; Geertzen, Jan H B; Dijkstra, Pieter U; Dekker, Rienk

    2018-05-31

    To explore ideas of the target population about a community-based intervention to stimulate physical activity in hard-to-reach physically disabled people. Semi-structured interviews were performed with 21 physically disabled people, and analyzed using thematic analyses. Findings were interpreted using the integrated Physical Activity for People with a Disability and Intervention Mapping model. The intervention should aim to stimulate intrinsic motivation and raise awareness for the health effects of physical activity. It should provide diverse activities, increase visibility of these activities, and improve image of physical activity for physically disabled people. Participants suggested to provide individual coaching sessions, increase marketing, present role models, and assign buddies. Potential users should be approached personally through intermediate organizations, or via social media and word of mouth promotion. Participants suggested that users, government, sponsors, and health insurers should finance the intervention. Self-responsibility for being physically active was strongly emphasized by participants. An intervention to stimulate physical activity in hard-to-reach physically disabled people should be individualized, include personal support, and should include marketing to improve image of physical activity of physically disabled people. The intervention that fulfills these requirements should be developed and tested for effects in future research. Implications for rehabilitation An intervention to stimulate physical activity in physically disabled people should aim to raise awareness for the health effects of physical activity, stimulate intrinsic motivation, offer diverse activities, increase the visibility of the possible activities, and improve the image of physical activity for physically disabled people. An intervention should include both individual- and environmental-level intervention methods. Physically disabled people most emphasized

  8. Sitting ducks face chronic disease: an analysis of newspaper coverage of sedentary behaviour as a health issue in Australia 2000-2012.

    PubMed

    Chau, Josephine Y; Bonfiglioli, Catriona; Zhong, Amy; Pedisic, Zeljko; Daley, Michelle; McGill, Bronwyn; Bauman, Adrian

    2017-08-01

    Issue addressed This study examines how sedentary behaviour (too much sitting) was covered as a health issue by Australian newspapers and how physical activity was framed within this newspaper coverage. Methods Articles featuring sedentary behaviour published in Australian newspapers between 2000 and 2012 were analysed for content and framing. Main outcome measures were volume, number and content of newspaper articles; framing and types of sedentary behaviour; responsibility for the problem of and solutions to high levels of sedentary behaviour; and physical activity mentions and how it was framed within sedentary behaviour coverage. Results Out of 48 articles, prolonged sitting was framed as bad for health (52%) and specifically as health compromising for office workers (25%). Adults who sat a lot were framed as 'easy targets' for ill health (21% of headlines led with 'sitting ducks' or 'sitting targets'). Prolonged sitting was framed as an issue of individual responsibility (>90%) with less mention of environmental and sociocultural contributors. Thirty-six of 48 articles mentioned physical activity; 39% stated that being physically active does not matter if a person sits for prolonged periods of time or that the benefits of physical activity are undone by too much sitting. Conclusions News coverage should reflect the full socio-ecological model of sedentary behaviour and continually reinforce the independent and well-established benefits of health-enhancing physical activity alongside the need to limit prolonged sitting. So what? It is important that the entire 'move more, sit less, every day!' message is communicated by news media.

  9. Increasing Children's Voluntary Physical Activity Outside of School Hours Through Targeting Social Cognitive Theory Variables.

    PubMed

    Annesi, James J; Walsh, Stephanie M; Greenwood, Brittney L

    2016-10-01

    Volume of moderate-to-vigorous physical activity completed during the elementary school day is insufficient, and associated with health risks. Improvements in theory-based psychosocial factors might facilitate increased out-of-school physical activity. A behaviorally based after-school care protocol, Youth Fit 4 Life, was tested for its association with increased voluntary, out-of-school physical activity and improvements in its theory-based psychosocial predictors in 9- to 12-year-olds. Increases over 12 weeks in out-of-school physical activity, and improvements in self-regulation for physical activity, exercise self-efficacy, and mood, were significantly greater in the Youth Fit 4 Life group (n = 88) when contrasted with a typical care control group (n = 57). Changes in the 3 psychosocial variables significantly mediated the group-physical activity change relationship (R(2) = .31, P < .001). Change in self-regulation was a significant independent mediator, and had a reciprocal relationship with change in out-of-school physical activity. In the Youth Fit 4 Life group, occurrence of 300 min/wk of overall physical activity increased from 41% to 71%. Targeting theory-based psychosocial changes within a structured after-school care physical activity program was associated with increases in children's overall time being physically active. After replication, large scale application will be warranted. © The Author(s) 2016.

  10. Cost-effectiveness of health promotion targeting physical activity and healthy eating in mental health care.

    PubMed

    Verhaeghe, Nick; De Smedt, Delphine; De Maeseneer, Jan; Maes, Lea; Van Heeringen, Cornelis; Annemans, Lieven

    2014-08-18

    There is a higher prevalence of obesity in individuals with mental disorders compared to the general population. The results of several studies suggested that weight reduction in this population is possible following psycho-educational and/or behavioural weight management interventions. Evidence of the effectiveness alone is however inadequate for policy making. The aim of the current study was to evaluate the cost-effectiveness of a health promotion intervention targeting physical activity and healthy eating in individuals with mental disorders. A Markov decision-analytic model using a public payer perspective was applied, projecting the one-year results of a 10-week intervention over a time horizon of 20 years, assuming a repeated yearly implementation of the programme. Scenario analysis was applied evaluating the effects on the results of alternative modelling assumptions. One-way sensitivity analysis was performed to assess the effects on the results of varying key input parameters. An incremental cost-effectiveness ratio of 27,096€/quality-adjusted life years (QALY) in men, and 40,139€/QALY in women was found in the base case. Scenario analysis assuming an increase in health-related quality of life as a result of the body mass index decrease resulted in much better cost-effectiveness in both men (3,357€/QALY) and women (3,766€/QALY). The uncertainty associated with the intervention effect had the greatest impact on the model. As far as is known to the authors, this is the first health economic evaluation of a health promotion intervention targeting physical activity and healthy eating in individuals with mental disorders. Such research is important as it provides payers and governments with better insights how to spend the available resources in the most efficient way. Further research examining the cost-effectiveness of health promotion targeting physical activity and healthy eating in individuals with mental disorders is required.

  11. Trunk-arm coordination in reaching for moving targets in people with Parkinson's disease: comparison between virtual and physical reality.

    PubMed

    Ma, Hui-Ing; Hwang, Wen-Juh; Wang, Ching-Yi; Fang, Jing-Jing; Leong, Iat-Fai; Wang, Tsui-Ying

    2012-10-01

    We used a trunk-assisted prehension task to examine the effect of task (reaching for stationary vs. moving targets) and environmental constraints (virtual reality [VR] vs. physical reality) on the temporal control of trunk and arm motions in people with Parkinson's disease (PD). Twenty-four participants with PD and 24 age-matched controls reached for and grasped a ball that was either stationary or moving along a ramp 120% of arm length away. In a similar VR task, participants reached for a virtual ball that was either stationary or moving. Movement speed was measured as trunk and arm movement times (MTs); trunk-arm coordination was measured as onset interval and offset interval between trunk and arm motions, as well as a summarized index-desynchrony score. In both VR and physical reality, the PD group had longer trunk and arm MTs than the control group when reaching for stationary balls (p<.001). When reaching for moving balls in VR and physical reality, however, the PD group had lower trunk and arm MTs, onset intervals, and desynchrony scores (p<.001). For the PD group, VR induced shorter trunk MTs, shorter offset intervals, and lower desynchrony scores than did physical reality when reaching for moving balls (p<.001). These findings suggest that using real moving targets in trunk-assisted prehension tasks improves the speed and synchronization of trunk and arm motions in people with PD, and that using virtual moving targets may induce a movement termination strategy different from that used in physical reality. Copyright © 2012 Elsevier B.V. All rights reserved.

  12. Comparison of virtual reality versus physical reality on movement characteristics of persons with Parkinson's disease: effects of moving targets.

    PubMed

    Wang, Ching-Yi; Hwang, Wen-Juh; Fang, Jing-Jing; Sheu, Ching-Fan; Leong, Iat-Fai; Ma, Hui-Ing

    2011-08-01

    To compare the performance of reaching for stationary and moving targets in virtual reality (VR) and physical reality in persons with Parkinson's disease (PD). A repeated-measures design in which all participants reached in physical reality and VR under 5 conditions: 1 stationary ball condition and 4 conditions with the ball moving at different speeds. University research laboratory. Persons with idiopathic PD (n=29) and age-matched controls (n=25). Not applicable. Success rates and kinematics of arm movement (movement time, amplitude of peak velocity, and percentage of movement time for acceleration phase). In both VR and physical reality, the PD group had longer movement time (P<.001) and lower peak velocity (P<.001) than the controls when reaching for stationary balls. When moving targets were provided, the PD group improved more than the controls did in movement time (P<.001) and peak velocity (P<.001), and reached a performance level similar to that of the controls. Except for the fastest moving ball condition (0.5-s target viewing time), which elicited worse performance in VR than in physical reality, most cueing conditions in VR elicited performance generally similar to those in physical reality. Although slower than the controls when reaching for stationary balls, persons with PD increased movement speed in response to fast moving balls in both VR and physical reality. This suggests that with an appropriate choice of cueing speed, VR is a promising tool for providing visual motion stimuli to improve movement speed in persons with PD. More research on the long-term effect of this type of VR training program is needed. Copyright © 2011 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  13. Dendrimers in drug delivery and targeting: Drug-dendrimer interactions and toxicity issues

    PubMed Central

    Madaan, Kanika; Kumar, Sandeep; Poonia, Neelam; Lather, Viney; Pandita, Deepti

    2014-01-01

    Dendrimers are the emerging polymeric architectures that are known for their defined structures, versatility in drug delivery and high functionality whose properties resemble with biomolecules. These nanostructured macromolecules have shown their potential abilities in entrapping and/or conjugating the high molecular weight hydrophilic/hydrophobic entities by host-guest interactions and covalent bonding (prodrug approach) respectively. Moreover, high ratio of surface groups to molecular volume has made them a promising synthetic vector for gene delivery. Owing to these properties dendrimers have fascinated the researchers in the development of new drug carriers and they have been implicated in many therapeutic and biomedical applications. Despite of their extensive applications, their use in biological systems is limited due to toxicity issues associated with them. Considering this, the present review has focused on the different strategies of their synthesis, drug delivery and targeting, gene delivery and other biomedical applications, interactions involved in formation of drug-dendrimer complex along with characterization techniques employed for their evaluation, toxicity problems and associated approaches to alleviate their inherent toxicity. PMID:25035633

  14. Target: Lifestyle.

    ERIC Educational Resources Information Center

    Poehlman, Eric T.

    1985-01-01

    "Target: Lifestyle" is a physical education curriculum adopted by Detroit Country Day School which incorporates instruction in nutrition, physical fitness, first aid, and lifetime sports. This curriculum aims to influence student attitudes and lifestyles in health and physical fitness. Four levels of instruction are described. (DF)

  15. Inertial Fusion Target Physics Advantages with the Krypton Fluoride Laser

    NASA Astrophysics Data System (ADS)

    Obenschain, Stephen

    2010-11-01

    The krypton fluoride (KrF) laser's short wavelength, broad bandwidth and capability to provide extremely uniform target illumination are advantages towards obtaining high gain direct drive implosions. The short wavelength helps suppress deleterious laser-plasma instabilities, and allows one to employ higher ablation pressures. In addition, the KrF architecture allows one to zoom down the focal diameter to follow the size of the imploding pellet, thereby improving the coupling efficiency. The NRL researchers have been conducting theoretical and experimental studies to quantify the beneficial effects of utilizing KrF light. Experiments using the Nike facility have confirmed that KrF light significantly increases the threshold for laser-plasma instability. This presentation will discuss the observed target physics with KrF light and its effects towards facilitating the high gains needed for power production with inertial fusion. Simulations indicate that shock ignited designs can achieve gains above 200 with KrF energies as low a 1 megajoule. For fusion energy a laser driver must be capable of high repetition rates (5-10 Hz) along with adequate efficiency and durability. The Electra KrF 30-cm aperture electron-beam-pumped amplifier has demonstrated long duration continuous operation at high-repetition rates. This and other advances show that the KrF laser should be able to meet the requirements.

  16. Decoupled tracking and thermal monitoring of non-stationary targets.

    PubMed

    Tan, Kok Kiong; Zhang, Yi; Huang, Sunan; Wong, Yoke San; Lee, Tong Heng

    2009-10-01

    Fault diagnosis and predictive maintenance address pertinent economic issues relating to production systems as an efficient technique can continuously monitor key health parameters and trigger alerts when critical changes in these variables are detected, before they lead to system failures and production shutdowns. In this paper, we present a decoupled tracking and thermal monitoring system which can be used on non-stationary targets of closed systems such as machine tools. There are three main contributions from the paper. First, a vision component is developed to track moving targets under a monitor. Image processing techniques are used to resolve the target location to be tracked. Thus, the system is decoupled and applicable to closed systems without the need for a physical integration. Second, an infrared temperature sensor with a built-in laser for locating the measurement spot is deployed for non-contact temperature measurement of the moving target. Third, a predictive motion control system holds the thermal sensor and follows the moving target efficiently to enable continuous temperature measurement and monitoring.

  17. Advances in target design for heavy ion fusion

    NASA Astrophysics Data System (ADS)

    Callahan, D. A.; Tabak, M.; Bennett, G. R.; Cuneo, M. E.; Vesey, R. A.; Nikroo, A.; Czechowicz, D.; Steinman, D.

    2005-12-01

    Over the past few years, the emphasis in heavy ion target design has moved from the distributed radiator target to the 'hybrid' target because the hybrid target allows a larger beam focal spot than the distributed radiator (~5 mm radius rather than ~2 mm radius). The larger spot relaxes some of the requirements on the driver, but introduces some new target physics issues. Most notable is the use of shine shields and shims in the hohlraum to achieve symmetry rather than achieving symmetry by beam placement. The shim is a thin layer of material placed on or near the capsule surface to block a small amount of excess radiation. While we have been developing this technique for the heavy ion hybrid target, the technique can also be used in any indirect drive target. We have begun testing the concept of a shim to improve symmetry using a double-ended z-pinch hohlraum on the Sandia Z-machine. Experiments using shimmed thin wall capsules have shown that we can reverse the sign of a P2 asymmetry and significantly reduce the size of a P4 asymmetry. These initial experiments demonstrate the concept of a shim as another method for controlling early time asymmetries in ICF capsules.

  18. Randomized controlled trial of a behavioral intervention targeting symptoms and physical activity in multiple sclerosis.

    PubMed

    Pilutti, L A; Dlugonski, D; Sandroff, B M; Klaren, R; Motl, R W

    2014-04-01

    Exercise training is beneficial, but most persons with multiple sclerosis (MS) are sedentary and physically inactive. This has prompted a new focus on the promotion of lifestyle physical activity in MS. We previously designed, tested, and refined a behavioral intervention delivered through the Internet that successfully increased lifestyle physical activity in MS, but have not evaluated the effects on secondary symptomatic and health-related quality of life (HRQOL) outcomes. We conducted a 6-month randomized controlled trial (RCT) that examined the efficacy of an Internet-delivered, behavioral intervention for improving outcomes of fatigue, depression, anxiety, pain, sleep quality, and HRQOL in 82 ambulatory persons with MS. The secondary aim was to replicate previous results regarding change in free-living physical activity. There was a significant and positive effect of the intervention on fatigue severity (p=.001, η ρ (2)=.15) and its physical impact (p=.008, η ρ (2)=.09), depression (p=.006, η ρ (2)=.10), and anxiety (p=.006, η ρ (2)=.10). There were non-significant improvements in pain (p=.08, η ρ (2)=.04), sleep quality (p=.06, η ρ (2)=.05), and physical HRQOL (p=.06, η ρ (2)=.05). We replicated our previous results by demonstrating an increase in self-reported physical activity (p=.001, η ρ (2)=.13). Our results support behavioral interventions targeting lifestyle physical activity as an alternative approach for managing symptoms in MS.

  19. A Context Menu for the Real World: Controlling Physical Appliances Through Head-Worn Infrared Targeting

    DTIC Science & Technology

    2013-12-10

    Edward A. Lee Björn Hartmann Electrical Engineering and Computer Sciences University of California at Berkeley Technical Report No. UCB/EECS-2013-200...NAME(S) AND ADDRESS(ES) University of California at Berkeley, Electrical Engineering and Computer Sciences,Berkeley,CA,94720 8. PERFORMING...movement. PHYSICAL TARGET ACQUISITION STUDY To understand the accuracy and performance of head- orientation-based selection through our device, we car - ried

  20. Effects of a Target-Task Problem-Solving Model on Senior Secondary School Students' Performance in Physics

    ERIC Educational Resources Information Center

    Olaniyan, A. O.; Omosewo, E. O.

    2015-01-01

    The study investigated the Effects of a Target-Task Problem-Solving Model on Senior Secondary School Students' Performance in Physics. The research design was a quasi-experimental, non-randomized, non-equivalent pretest, post-test using a control group. The study was conducted in two schools purposively selected and involved a total of 120 Senior…

  1. Contexts, Mechanisms, and Outcomes That Matter in Dutch Community-Based Physical Activity Programs Targeting Socially Vulnerable Groups.

    PubMed

    Herens, Marion; Wagemakers, Annemarie; Vaandrager, Lenneke; van Ophem, Johan; Koelen, Maria

    2017-09-01

    This article presents a practitioner-based approach to identify key combinations of contextual factors (C) and mechanisms (M) that trigger outcomes (O) in Dutch community-based health-enhancing physical activity (CBHEPA) programs targeting socially vulnerable groups. Data were collected in six programs using semi-structured interviews and focus groups using a timeline technique. Sessions were recorded, anonymized, and transcribed. A realist synthesis protocol was used for data-driven and thematic analysis of CMO configurations. CMO configurations related to community outreach, program sustainability, intersectoral collaboration, and enhancing participants' active lifestyles. We have refined the CBHEPA program theory by showing that actors' passion for, and past experiences with, physical activity programs trigger outcomes, alongside their commitment to socially vulnerable target groups. Project discontinuity, limited access to resources, and a trainer's stand-alone position were negative configurations. The authors conclude that local governance structures appear often to lack adaptive capacity to accommodate multilevel processes to sustain programs.

  2. A typology of middle school girls: audience segmentation related to physical activity.

    PubMed

    Staten, Lisa K; Birnbaum, Amanda S; Jobe, Jared B; Elder, John P

    2006-02-01

    The Trial of Activity for Adolescent Girls (TAAG) combines social ecological and social marketing approaches to promote girls' participation in physical activity programs implemented at 18 middle schools throughout the United States. Key to the TAAG approach is targeting materials to a variety of audience segments. TAAG segments are individuals who share one or more common characteristic that is expected to correlate with physical activity. Thirteen focus groups with seventh and eighth grade girls were conducted to identify and characterize segments. Potential messages and channels of communication were discussed for each segment. Based on participant responses, six primary segments were identified: athletic, preppy, quiet, rebel, smart, and tough. The focus group information was used to develop targeted promotional tools to appeal to a diversity of girls. Using audience segmentation for targeting persuasive communication is potentially useful for intervention programs but may be sensitive; therefore, ethical issues must be critically examined.

  3. Physical property control in core/shell inorganic nanostructures for fluorescence and magnetic targeting applications

    NASA Astrophysics Data System (ADS)

    Roberts, Stephen K.

    Nanomaterials show immense promise for the future in numerous areas of application. Properties that are unique from the bulk material and are tunable allow for innovation in material design. This thesis will focus on controlling the physical properties of core/shell nanostructures to enhance the utility of the materials. The first focus is on the impact of different solvent mixtures during the shell growth phase of SILAR based core/shell quantum dot synthesis is studied. Gaining insight into the mechanism for SILAR growth of core/shell nanoparticles allows improved synthetic yields and precursor binding, providing enhanced control to synthesis of core/shell nanoparticles. The second focus of this thesis is exploring the use of magnetic nanoparticles for magnetic drug targeting for cardiovascular conditions. Magnetic targeting for drug delivery enables increased local drug concentration, while minimizing non-specific interactions. In order to be effective for magnetic targeting, it must be shown that low magnetic strength is sufficient to capture flowing nanoparticles. By demonstrating the binding of a therapeutic agent to the surface at medicinal levels, the viability for use as a nanoparticle drug delivery system is improved.

  4. Addressing Issues of Workplace Harassment: Counseling the Targets.

    ERIC Educational Resources Information Center

    Lewis, Jacqueline; Coursol, Diane; Wahl, Kay Herting

    2002-01-01

    Workplace harassment includes dysfunctional personal interactions characterized by bullying behaviors, personal attacks, and attempts to denigrate others. Targets of workplace harassment may experience stress, depression, low self-esteem, loss of sleep, and even posttraumatic stress disorder. Strategies that counselors can use to work effectively…

  5. Large system change challenges: addressing complex critical issues in linked physical and social domains

    NASA Astrophysics Data System (ADS)

    Waddell, Steve; Cornell, Sarah; Hsueh, Joe; Ozer, Ceren; McLachlan, Milla; Birney, Anna

    2015-04-01

    Most action to address contemporary complex challenges, including the urgent issues of global sustainability, occurs piecemeal and without meaningful guidance from leading complex change knowledge and methods. The potential benefit of using such knowledge is greater efficacy of effort and investment. However, this knowledge and its associated tools and methods are under-utilized because understanding about them is low, fragmented between diverse knowledge traditions, and often requires shifts in mindsets and skills from expert-led to participant-based action. We have been engaged in diverse action-oriented research efforts in Large System Change for sustainability. For us, "large" systems can be characterized as large-scale systems - up to global - with many components, of many kinds (physical, biological, institutional, cultural/conceptual), operating at multiple levels, driven by multiple forces, and presenting major challenges for people involved. We see change of such systems as complex challenges, in contrast with simple or complicated problems, or chaotic situations. In other words, issues and sub-systems have unclear boundaries, interact with each other, and are often contradictory; dynamics are non-linear; issues are not "controllable", and "solutions" are "emergent" and often paradoxical. Since choices are opportunity-, power- and value-driven, these social, institutional and cultural factors need to be made explicit in any actionable theory of change. Our emerging network is sharing and building a knowledge base of experience, heuristics, and theories of change from multiple disciplines and practice domains. We will present our views on focal issues for the development of the field of large system change, which include processes of goal-setting and alignment; leverage of systemic transitions and transformation; and the role of choice in influencing critical change processes, when only some sub-systems or levels of the system behave in purposeful ways

  6. Factors affecting physical therapists’ job satisfaction: questionnaire survey targeting first-year physical therapists

    PubMed Central

    Kota, Munetsugu; Kudo, Hiroyuki; Okita, Kazuhiko

    2018-01-01

    [Purpose] The survey aimed to clarify the factors that affect physiotherapists’ job satisfaction. [Subjects and Methods] To examine factors affecting physical therapists’ job satisfaction using a cross-sectional study with a questionnaire survey. Subjects were 193 first-year physical therapists who participated in a newcomer orientation at Hiroshima Prefectural Physical Therapy Association. The questionnaire comprised items concerning physical therapists’ satisfaction with their work, motives for becoming physical therapists, education in school, internships, the workplace, and comfort in the workplace. [Results] Subjects were divided into two groups according to their satisfaction with their occupation. The “high satisfaction” group included 157 subjects, and the group “low satisfaction” group included 36 subjects. Using logistic regression analysis, items concerning comfort in the workplace, motives for becoming physical therapists, and learning in school were analysed. [Conclusion] Factors affecting physical therapists’ job satisfaction were primarily influenced by previous experience and working conditions. PMID:29706706

  7. Factors affecting physical therapists' job satisfaction: questionnaire survey targeting first-year physical therapists.

    PubMed

    Kota, Munetsugu; Kudo, Hiroyuki; Okita, Kazuhiko

    2018-04-01

    [Purpose] The survey aimed to clarify the factors that affect physiotherapists' job satisfaction. [Subjects and Methods] To examine factors affecting physical therapists' job satisfaction using a cross-sectional study with a questionnaire survey. Subjects were 193 first-year physical therapists who participated in a newcomer orientation at Hiroshima Prefectural Physical Therapy Association. The questionnaire comprised items concerning physical therapists' satisfaction with their work, motives for becoming physical therapists, education in school, internships, the workplace, and comfort in the workplace. [Results] Subjects were divided into two groups according to their satisfaction with their occupation. The "high satisfaction" group included 157 subjects, and the group "low satisfaction" group included 36 subjects. Using logistic regression analysis, items concerning comfort in the workplace, motives for becoming physical therapists, and learning in school were analysed. [Conclusion] Factors affecting physical therapists' job satisfaction were primarily influenced by previous experience and working conditions.

  8. A Typology of Middle School Girls: Audience Segmentation Related to Physical Activity

    PubMed Central

    Staten, Lisa K.; Birnbaum, Amanda S.; Jobe, Jared B.; Elder, John P.

    2008-01-01

    The Trial of Activity for Adolescent Girls (TAAG) combines social ecological and social marketing approaches to promote girls’ participation in physical activity programs implemented at 18 middle schools throughout the United States. Key to the TAAG approach is targeting materials to a variety of audience segments. TAAG segments are individuals who share one or more common characteristic that is expected to correlate with physical activity. Thirteen focus groups with seventh and eighth grade girls were conducted to identify and characterize segments. Potential messages and channels of communication were discussed for each segment. Based on participant responses, six primary segments were identified: athletic, preppy, quiet, rebel, smart, and tough. The focus group information was used to develop targeted promotional tools to appeal to a diversity of girls. Using audience segmentation for targeting persuasive communication is potentially useful for intervention programs but may be sensitive; therefore, ethical issues must be critically examined. PMID:16397160

  9. Curricular Issues in Urban High School Physical Education

    ERIC Educational Resources Information Center

    Schmidlein, Robert; Vickers, Brad; Chepyator-Thomson, Rose

    2014-01-01

    Urban physical education curriculum articles are sparsely published in major educational journals (Chepyator-Thomson et al., 2008; Culp, 2005). This leaves urban physical educators the daunting task to modify and prepare curriculum based on formal class training and educational workshops and to interpret journal articles to be applied to the urban…

  10. Understanding Laser-Imprint Effects on Plastic-Target Implosions on OMEGA with New Physics Models

    NASA Astrophysics Data System (ADS)

    Hu, S. X.; Michel, D. T.; Davis, A. K.; Betti, R.; Radha, P. B.; Campbell, E. M.; Froula, D. H.; Stoeckl, C.

    2016-10-01

    Using the state-of-the-art physics models (nonlocal thermal transport, cross-beam energy transfer, and first-principles equation of state) recently implemented in our two-dimensional hydrocode DRACO, we have performed a systematic study of laser-imprint effects on plastic-target implosions on OMEGA by both simulations and experiments. Through varying the laser picket intensity, the imploding shells were set at different adiabats ranging from α = 2 to α = 6 . As the shell adiabat α decreases, we observed: (1) the measured shell thickness at the hot spot emission becomes larger than the uniform prediction; (2) the hot-spot core emits and neutron burn starts earlier than the corresponding 1-D prediction; and (3) the measured neutron yields are significantly reduced from their 1-D designs. Most of these experimental observations are well reproduced by our DRACO simulations with laser imprints. These studies clearly identify that laser imprint is the major cause for target performance degradation of OMEGA implosions of α <= 3 . Mitigating laser imprints must be an essential effort to improve low- α target performance in direct-drive inertial confinement fusion ignition attempts. This material is based upon work supported by the Department of Energy National Nuclear Security Administration under Award Number DE-NA0001944.

  11. Management of falls in community-dwelling older adults: clinical guidance statement from the Academy of Geriatric Physical Therapy of the American Physical Therapy Association.

    PubMed

    Avin, Keith G; Hanke, Timothy A; Kirk-Sanchez, Neva; McDonough, Christine M; Shubert, Tiffany E; Hardage, Jason; Hartley, Greg

    2015-06-01

    Falls in older adults are a major public health concern due to high prevalence, impact on health outcomes and quality of life, and treatment costs. Physical therapists can play a major role in reducing fall risk for older adults; however, existing clinical practice guidelines (CPGs) related to fall prevention and management are not targeted to physical therapists. The purpose of this clinical guidance statement (CGS) is to provide recommendations to physical therapists to help improve outcomes in the identification and management of fall risk in community-dwelling older adults. The Subcommittee on Evidence-Based Documents of the Practice Committee of the Academy of Geriatric Physical Therapy developed this CGS. Existing CPGs were identified by systematic search and critically appraised using the Appraisal of Guidelines, Research, and Evaluation in Europe II (AGREE II) tool. Through this process, 3 CPGs were recommended for inclusion in the CGS and were synthesized and summarized. Screening recommendations include asking all older adults in contact with a health care provider whether they have fallen in the previous year or have concerns about balance or walking. Follow-up should include screening for balance and mobility impairments. Older adults who screen positive should have a targeted multifactorial assessment and targeted intervention. The components of this assessment and intervention are reviewed in this CGS, and barriers and issues related to implementation are discussed. A gap analysis supports the need for the development of a physical therapy-specific CPG to provide more precise recommendations for screening and assessment measures, exercise parameters, and delivery models. This CGS provides recommendations to assist physical therapists in the identification and management of fall risk in older community-dwelling adults. © 2015 American Physical Therapy Association.

  12. Surveillance of Social and Geographic Inequalities in Housing-Related Issues: The Case of the Eastern Townships, Quebec (Canada)

    PubMed Central

    Roy, Mathieu; Généreux, Mélissa; Laverdière, Émélie; Vanasse, Alain

    2014-01-01

    Even though health inequalities are conditioned by many aspects of the environment, much of the existing research focuses on the social environment. This emphasis has the effect to neglect other environmental aspects such as its physical dimension. The physical environment, which is linked to housing conditions, may contribute to the uneven distribution of health. In this study, we examined 19 housing-related issues among a representative sample of 2,000 adults residing in a Quebec (Canada) health region characterized by a mix of rural, semi-rural, and urban areas. The distribution of these issues was examined according to socioeconomic and geographic indicators of social position. Summary measures of inequalities were assessed. Our results showed that the prevalence of nearly all housing-related issues was higher among low-income households compared to more affluent ones. Highly educated individuals showed better housing conditions, whereas different issues tended to cluster in deprived or densely populated areas. To conclude, we observed steep gradients between social class and poor housing conditions. This may explain a substantial part of health inequality on the regional scale. The surveillance of housing-related issues is therefore essential to properly inform and mobilize local stakeholders and to develop interventions that target vulnerable groups on this level. PMID:24806192

  13. Physical security and cyber security issues and human error prevention for 3D printed objects: detecting the use of an incorrect printing material

    NASA Astrophysics Data System (ADS)

    Straub, Jeremy

    2017-06-01

    A wide variety of characteristics of 3D printed objects have been linked to impaired structural integrity and use-efficacy. The printing material can also have a significant impact on the quality, utility and safety characteristics of a 3D printed object. Material issues can be created by vendor issues, physical security issues and human error. This paper presents and evaluates a system that can be used to detect incorrect material use in a 3D printer, using visible light imaging. Specifically, it assesses the ability to ascertain the difference between materials of different color and different types of material with similar coloration.

  14. Physics Matters: An Introduction to Conceptual Physics

    NASA Astrophysics Data System (ADS)

    Trefil, James; Hazen, Robert M.

    2003-12-01

    From amusement park rides to critical environmental issues such as energy generation-physics affects almost every aspect of our world. In PHYSICS MATTERS, James Trefil and Robert Hazen examine the fundamental physics principles at work behind the many practical applications that fuel our society and individual lives. Their goal is to promote a deeper understanding of how the great ideas of physics connect to form a much larger understanding of the universe in which we live. Highlights Helps readers build a general knowledge of key ideas in physics and their connection to technology and other areas of science. Promotes an appreciation of what science is, how scientific knowledge is developed, and how it differs from other intellectual activities. Examines modern technologies, including GPS, the Internet, and information technologies, as well as medical technologies, such as MRI, PET scans, CAT scans, and radioisotope tracers. Explores key issues facing the world today, such as global warning, nuclear waste, and government funding for research.

  15. Ethical Issues in Online Education

    ERIC Educational Resources Information Center

    Anderson, Bill; Simpson, Mary

    2007-01-01

    Teaching at a distance raises ethical issues particular to the distance context. When distance teaching is also online teaching, the situation is even more complex. Online teaching environments amplify the ethical issues faced by instructors and students. Online sites support complex discourses and multiple relationships; they cross physical,…

  16. A special issue on volcanic centers as targets for mineral exploration

    USGS Publications Warehouse

    Elston, Wolfgang E.; Plumlee, Geoffrey S.

    1994-01-01

    NEPTUNE or Pluto? Since the days of Hutton and Werner, every generation of economic geologists has addressed this question in a new light. Most papers in this special issue deal with the thin and leaky roof of Pluto's underworld. It allows hot emanations from Hades to leak out, only to be quenched and diluted by waters percolating down from Neptune's realm. The title of the special issue was taken from a symposium held in Albuquerque, New Mexico, on April 24, 1991, during a joint meeting of the Rocky Mountain and South-Central Sections of the Geological Society of America. More than half of the present authors participated. Although no restrictions were placed on subject matter in the original call for papers, all of the articles in this special issue deal with mineralization related to continental or epicontinental siliceous volcanism. One of us (Elston) summarizes them in his contribution. More than three years have passed since the call for manuscripts was issued. Their preparation, technical editing, reviewing, revision, and copy editing turned out to be a formidable task. Our sincere thanks are due to authors, reviewers, and the staff of Economic Geology for their hard work, dedication, and patience.

  17. Management of Falls in Community-Dwelling Older Adults: Clinical Guidance Statement From the Academy of Geriatric Physical Therapy of the American Physical Therapy Association

    PubMed Central

    Avin, Keith G.; Hanke, Timothy A.; Kirk-Sanchez, Neva; McDonough, Christine M.; Shubert, Tiffany E.; Hartley, Greg

    2015-01-01

    Background Falls in older adults are a major public health concern due to high prevalence, impact on health outcomes and quality of life, and treatment costs. Physical therapists can play a major role in reducing fall risk for older adults; however, existing clinical practice guidelines (CPGs) related to fall prevention and management are not targeted to physical therapists. Objective The purpose of this clinical guidance statement (CGS) is to provide recommendations to physical therapists to help improve outcomes in the identification and management of fall risk in community-dwelling older adults. Design and Methods The Subcommittee on Evidence-Based Documents of the Practice Committee of the Academy of Geriatric Physical Therapy developed this CGS. Existing CPGs were identified by systematic search and critically appraised using the Appraisal of Guidelines, Research, and Evaluation in Europe II (AGREE II) tool. Through this process, 3 CPGs were recommended for inclusion in the CGS and were synthesized and summarized. Results Screening recommendations include asking all older adults in contact with a health care provider whether they have fallen in the previous year or have concerns about balance or walking. Follow-up should include screening for balance and mobility impairments. Older adults who screen positive should have a targeted multifactorial assessment and targeted intervention. The components of this assessment and intervention are reviewed in this CGS, and barriers and issues related to implementation are discussed. Limitations A gap analysis supports the need for the development of a physical therapy–specific CPG to provide more precise recommendations for screening and assessment measures, exercise parameters, and delivery models. Conclusion This CGS provides recommendations to assist physical therapists in the identification and management of fall risk in older community-dwelling adults. PMID:25573760

  18. Production of 9Be targets for nuclear physics experiments

    NASA Astrophysics Data System (ADS)

    Marín-Lámbarri, D. J.; Kheswa, N. Y.

    2018-05-01

    Self-supporting beryllium (9Be) targets were produced by mechanical rolling method in which a double pack technique was implemented. Targets were used for the investigation of the low-lying excitation energy region in 9B through the 9Be(3He,t)9B reaction at the K600 spectrometer, at iThemba LABS facility. Beryllium is a semi-metal in nature and this makes it hard to deform by rolling or vacuum evaporate as a self-supporting target. Therefore heat treatment was needed to avoid brittleness and breakage of the material during rolling process. A description is given on how beryllium targets were manufactured.

  19. Introduction to spallation physics and spallation-target design

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Russell, G.J.; Pitcher, E.J.; Daemen, L.L.

    1995-10-01

    When coupled with the spallation process in appropriate target materials, high-power accelerators can be used to produce large numbers of neutrons, thus providing an alternate method to the use of nuclear reactors for this purpose. Spallation offers exciting new possibilities for generating intense neutron fluxes for a variety of applications, including: (a) spallation-neutron sources for materials science research; (b) accelerator-based production of tritium; (c) accelerator-based transmutation of waste; (d) accelerator-based destruction of plutonium; and (e) radioisotope production for medical and energy applications. Target design plays a key role in these applications, with neutron production/leakage being strongly dependent on the incidentmore » particle type and energy, and target material and geometry.« less

  20. Parent-targeted mobile phone intervention to increase physical activity in sedentary children: randomized pilot trial.

    PubMed

    Newton, Robert L; Marker, Arwen M; Allen, H Raymond; Machtmes, Ryan; Han, Hongmei; Johnson, William D; Schuna, John M; Broyles, Stephanie T; Tudor-Locke, Catrine; Church, Timothy S

    2014-11-10

    Low levels of moderate-to-vigorous physical activity are associated with adverse health consequences. The intent of the study was to determine the feasibility and efficacy of a 12-week physical activity promotion program targeting children, which was delivered to parents through mobile phones. Potential participants were recruited through advertisements placed in the newspaper, local hospitals and schools, and an email listserv. Sedentary children aged 6-10 years were randomly assigned to a minimal (MIG) or intensive (IIG) intervention group. Parents in the MIG were given a goal to increase (within 1 month) and maintain their child's activity at 6000 pedometer steps/day above their baseline levels and to monitor their child's steps daily. Parents in the IIG were given the same steps/day and monitoring goals, in addition to text messages and articles containing additional behavioral strategies (based on the Social Cognitive Theory) designed to promote their child's physical activity. The intervention components were delivered via mobile phone. Anthropometrics, body composition, and questionnaires were administered in a clinic. Children wore a New Lifestyles pedometer (NL-1000) each day throughout the intervention and parents were to monitor their child's step counts daily. Out of 59 children who screened for the study, a total of 27 children (mean age 8.7, SD 1.4 years; 56%, 15/27 female; 59%, 16/27 African American) were enrolled and completed the study. Overall, 97.90% (2220/2268; 98.20%, 1072/1092 for MIG; 97.60%, 1148/1176 for IIG) of expected step data were successfully entered by the parent or study coordinator. Parents in the MIG and IIG were sent approximately 7 and 13 text messages per week, respectively, averaged over the course of the study. IIG parents accessed an average of 6.1 (SD 4.4) articles over the course of the intervention and accessed a fewer number of articles in the last month compared to the first 2 months of the study (P=.002). Children in

  1. Synergies between optical and physical variables in intercepting parabolic targets

    PubMed Central

    Gómez, José; López-Moliner, Joan

    2013-01-01

    Interception requires precise estimation of time-to-contact (TTC) information. A long-standing view posits that all relevant information for extracting TTC is available in the angular variables, which result from the projection of distal objects onto the retina. The different timing models rooted in this tradition have consequently relied on combining visual angle and its rate of expansion in different ways with tau being the most well-known solution for TTC. The generalization of these models to timing parabolic trajectories is not straightforward. For example, these different combinations rely on isotropic expansion and usually assume first-order information only, neglecting acceleration. As a consequence no optical formulations have been put forward so far to specify TTC of parabolic targets with enough accuracy. It is only recently that context-dependent physical variables have been shown to play an important role in TTC estimation. Known physical size and gravity can adequately explain observed data of linear and free-falling trajectories, respectively. Yet, a full timing model for specifying parabolic TTC has remained elusive. We here derive two formulations that specify TTC for parabolic ball trajectories. The first specification extends previous models in which known size is combined with thresholding visual angle or its rate of expansion to the case of fly balls. To efficiently use this model, observers need to recover the 3D radial velocity component of the trajectory which conveys the isotropic expansion. The second one uses knowledge of size and gravity combined with ball visual angle and elevation angle. Taking into account the noise due to sensory measurements, we simulate the expected performance of these models in terms of accuracy and precision. While the model that combines expansion information and size knowledge is more efficient during the late trajectory, the second one is shown to be efficient along all the flight. PMID:23720614

  2. Radioisotope Production for Medical and Physics Applications

    NASA Astrophysics Data System (ADS)

    Mausner, Leonard

    2012-10-01

    Radioisotopes are critical to the science and technology base of the US. Discoveries and applications made as a result of the availability of radioisotopes span widely from medicine, biology, physics, chemistry and homeland security. The clinical use of radioisotopes for medical diagnosis is the largest sector of use, with about 16 million procedures a year in the US. The use of ^99Mo/^99mTc generator and ^18F make up the majority, but ^201Tl, ^123I, ^111In, and ^67Ga are also used routinely to perform imaging of organ function. Application of radioisotopes for therapy is dominated by use of ^131I for thyroid malignancies, ^90Y for some solid tumors, and ^89Sr for bone cancer, but production of several more exotic species such as ^225Ac and ^211At are of significant current research interest. In physics ^225Ra is of interest for CP violation studies, and the actinides ^242Am, ^249Bk, and ^254Es are needed as targets for experiments to create superheavy elements. Large amounts of ^252Cf are needed as a fission source for the CARIBU experiment at ANL. The process of radioisotope production is multidisciplinary. Nuclear physics input based on nuclear reaction excitation function data is needed to choose an optimum target/projectile in order to maximize desired isotope production and minimize unwanted byproducts. Mechanical engineering is needed to address issues of target heating, induced mechanical stress and material compatibility of target and claddings. Radiochemists are involved as well since chemical separation to purify the desired final radioisotope product from the bulk target and impurities is also usually necessary. Most neutron rich species are produced at a few government and university reactors. Other radioisotopes are produced in cyclotrons in the commercial sector, university/hospital based facilities, and larger devices at the DOE labs. The landscape of US facilities, the techniques involved, and current supply challenges will be reviewed.

  3. The transformation of targeted killing and international order.

    PubMed

    Senn, Martin; Troy, Jodok

    2017-05-04

    This article introduces the special issue's question of whether and how the current transformation of targeted killing is transforming the global international order and provides the conceptual ground for the individual contributions to the special issue. It develops a two-dimensional concept of political order and introduces a theoretical framework that conceives the maintenance and transformation of international order as a dynamic interplay between its behavioral dimension in the form of violence and discursive processes and its institutional dimension in the form of ideas, norms, and rules. The article also conceptualizes targeted killing and introduces a typology of targeted-killing acts on the basis of their legal and moral legitimacy. Building on this conceptual groundwork, the article takes stock of the current transformation of targeted killing and summarizes the individual contributions to this special issue.

  4. Recent sheath physics studies on DIII-D

    NASA Astrophysics Data System (ADS)

    Watkins, J. G.; Labombard, B.; Stangeby, P. C.; Lasnier, C. J.; McLean, A. G.; Nygren, R. E.; Boedo, J. A.; Leonard, A. W.; Rudakov, D. L.

    2015-08-01

    A study to examine some current issues in the physics of the plasma sheath has been recently carried out in DIII-D low power Ohmic plasmas using both flush and domed Langmuir probes, divertor Thomson scattering (DTS), an infrared camera (IRTV), and a new calorimeter triple probe assembly mounted on the Divertor Materials Evaluation System (DIMES). The sheath power transmission factor was found to be consistent with the theoretically predicted value of 7 (±2) for low power plasmas. Using this factor, the three heat flux profiles derived from the LP, DTS, and calorimeter diagnostic measurements agree. Comparison of flush and domed Langmuir probes and divertor Thomson scattering indicates that proper interpretation of flush probe data to get target plate density and temperature is feasible and could potentially yield accurate measurements of target plate conditions where the probes are located.

  5. QM2017: Status and Key open Questions in Ultra-Relativistic Heavy-Ion Physics

    NASA Astrophysics Data System (ADS)

    Schukraft, Jurgen

    2017-11-01

    Almost exactly 3 decades ago, in the fall of 1986, the era of experimental ultra-relativistic E / m ≫ 1) heavy ion physics started simultaneously at the SPS at CERN and the AGS at Brookhaven with first beams of light Oxygen ions at fixed target energies of 200 GeV/A and 14.6 GeV/A, respectively. The event was announced by CERN [CERN's subatomic particle accelerators: Set up world-record in energy and break new ground for physics (CERN-PR-86-11-EN) (1986) 4 p, issued on 29 September 1986. URL (http://cds.cern.ch/record/855571)

  6. Mentoring in Physical Education: Issues and Insights.

    ERIC Educational Resources Information Center

    Mawer, Mick, Ed.

    These chapters describe partnerships and mentoring programs in the United Kingdom for initial teacher education. Part 1: The Context contains two chapters: "Partnerships in School-Based Training: The Implications for Physical Education" (Patricia Shenton and Elizabeth Murdoch); and "What Is Mentoring?" (Michael Taylor and Joan…

  7. Physical frailty, sarcopenia, and the enablement of autonomy: philosophical issues in geriatric medicine.

    PubMed

    Blasimme, Alessandro

    2017-02-01

    Physical frailty and loss of muscular mass (sarcopenia) are believed to be predictors of age-related conditions, such as disability and loss of autonomy. In this paper, I show that what in political and moral philosophy has come to be known as "the capability approach" may indeed provide much needed conceptual clarification in the area of frailty research. Other than being useful at the theoretical level, the capability approach can definitely help in the implementation of clinical guidelines and public health measures aimed at translating the results that are accumulating from frailty research. I will first briefly review the main philosophical tenets of the capability approach, and then analyze how they relate to current debates about frailty and sarcopenia by introducing the notion of "enablement". Finally, I will show how my analysis bears on both clinical research in this domain and public policy aimed at tackling some of the age-related issues in an aging society.

  8. Computational modeling of joint U.S.-Russian experiments relevant to magnetic compression/magnetized target fusion (MAGO/MTF)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sheehey, P.T.; Faehl, R.J.; Kirkpatrick, R.C.

    1997-12-31

    Magnetized Target Fusion (MTF) experiments, in which a preheated and magnetized target plasma is hydrodynamically compressed to fusion conditions, present some challenging computational modeling problems. Recently, joint experiments relevant to MTF (Russian acronym MAGO, for Magnitnoye Obzhatiye, or magnetic compression) have been performed by Los Alamos National Laboratory and the All-Russian Scientific Research Institute of Experimental Physics (VNIIEF). Modeling of target plasmas must accurately predict plasma densities, temperatures, fields, and lifetime; dense plasma interactions with wall materials must be characterized. Modeling of magnetically driven imploding solid liners, for compression of target plasmas, must address issues such as Rayleigh-Taylor instability growthmore » in the presence of material strength, and glide plane-liner interactions. Proposed experiments involving liner-on-plasma compressions to fusion conditions will require integrated target plasma and liner calculations. Detailed comparison of the modeling results with experiment will be presented.« less

  9. Undergraduate Physical Education Programs: Issues and Approaches.

    ERIC Educational Resources Information Center

    Lawson, Hal A., Ed.

    Papers presented at the National Professional Preparation Conference in Physical Education were revised and expanded for publication in this monograph. In part I, two papers, "Professional Preparation Conferences: One More Time" (W. G. Anderson) and "Current Context and Future Curriculum" (M. J. Ellis), set the stage for a presentation of…

  10. Physics Flash December 2016

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kippen, Karen Elizabeth

    This is the December 2016 issue of Physics Flash, the newsletter of the Physics Division of Los Alamos National Laboratory (LANL). In this issue, the following topics are covered: Novel liquid helium technique to aid highly sensitive search for a neutron electrical dipole moment; Silverleaf: Prototype Red Sage experiments performed at Q-site; John L. Kline named 2016 APS Fellow; Physics students in the news; First Entropy Engine quantum random number generator hits the market; and celebrating service.

  11. Racial and Gender Issues with Physics in the Pacific Region

    ERIC Educational Resources Information Center

    Aung, Than; Singh, Awnesh; Prasad, Uma

    2011-01-01

    This paper examines the state of physics teaching and learning in the Pacific Island nations. How have things changed in teaching physics? We believe that some of the goals and many of the challenges faced today have changed very little over the years. This paper is purely based upon the authors' experiences in teaching physics at the first-year…

  12. Issues in the Assessment of Physical Activity in Children

    ERIC Educational Resources Information Center

    Kang, Minsoo; Mahar, Matthew T.; Morrow, James R., Jr.

    2016-01-01

    Most people are aware of the important influence that physical activity has on health outcomes and quality of life, and it has become increasingly important to be able to determine how much physical activity individuals participate in on a regular basis so that tracking of behavior change can occur and individual or population interventions can be…

  13. Parent-Targeted Mobile Phone Intervention to Increase Physical Activity in Sedentary Children: Randomized Pilot Trial

    PubMed Central

    Marker, Arwen M; Allen, H Raymond; Machtmes, Ryan; Han, Hongmei; Johnson, William D; Schuna Jr, John M; Broyles, Stephanie T; Tudor-Locke, Catrine; Church, Timothy S

    2014-01-01

    Background Low levels of moderate-to-vigorous physical activity are associated with adverse health consequences. Objective The intent of the study was to determine the feasibility and efficacy of a 12-week physical activity promotion program targeting children, which was delivered to parents through mobile phones. Methods Potential participants were recruited through advertisements placed in the newspaper, local hospitals and schools, and an email listserv. Sedentary children aged 6-10 years were randomly assigned to a minimal (MIG) or intensive (IIG) intervention group. Parents in the MIG were given a goal to increase (within 1 month) and maintain their child’s activity at 6000 pedometer steps/day above their baseline levels and to monitor their child’s steps daily. Parents in the IIG were given the same steps/day and monitoring goals, in addition to text messages and articles containing additional behavioral strategies (based on the Social Cognitive Theory) designed to promote their child’s physical activity. The intervention components were delivered via mobile phone. Anthropometrics, body composition, and questionnaires were administered in a clinic. Children wore a New Lifestyles pedometer (NL-1000) each day throughout the intervention and parents were to monitor their child’s step counts daily. Results Out of 59 children who screened for the study, a total of 27 children (mean age 8.7, SD 1.4 years; 56%, 15/27 female; 59%, 16/27 African American) were enrolled and completed the study. Overall, 97.90% (2220/2268; 98.20%, 1072/1092 for MIG; 97.60%, 1148/1176 for IIG) of expected step data were successfully entered by the parent or study coordinator. Parents in the MIG and IIG were sent approximately 7 and 13 text messages per week, respectively, averaged over the course of the study. IIG parents accessed an average of 6.1 (SD 4.4) articles over the course of the intervention and accessed a fewer number of articles in the last month compared to the first

  14. Space Drive Physics: Introduction and Next Steps

    NASA Astrophysics Data System (ADS)

    Millis, M. G.

    Research toward the visionary goal of propellantless ``space drives'' is introduced, covering key physics issues and a listing of roughly 2-dozen approaches. The targeted advantage of a space drive is to circumvent the propellant constraints of rockets and the maneuvering limits of light sails by using the interactions between the spacecraft and its surrounding space for propulsion. At present, the scientific foundations from which to engineer a space drive have not been discovered and, objectively, might be impossible. Although no propulsion breakthroughs appear imminent, the subject has matured to where the relevant questions have been broached and are beginning to be answered. The critical make-break issues include; conservation of momentum, uncertain sources of reaction mass, and the net-external thrusting requirement. Note: space drives are not necessarily faster- than-light devices. Speed limits are a separate, unanswered issue. Relevant unsolved physics includes; the sources and mechanisms of inertial frames, coupling of gravitation and electromagnetism, and the nature of the quantum vacuum. The propulsion approaches span mostly stages 1 through 3 of the scientific method (defining the problem, collecting data, and articulating hypotheses), while some have matured to stage 4 (testing hypotheses). Nonviable approaches include `stiction drives,' `gyroscopic antigravity,' and `lifters.' No attempt is made to gauge the prospects of the remaining approaches. Instead, a list of next-step research questions is derived from the examination of these goals, unknowns, and concepts.

  15. Counseling Issues for Adult Women in Career Transition

    ERIC Educational Resources Information Center

    Ronzio, Cynthia R.

    2012-01-01

    This article addresses current psychosocial issues facing women in career transition and the implications of those issues for career counselors. Specifically, psychosocial developmental trajectories, the roles of family and relationships, the importance of underlying physical and mental health issues, and sociocultural and contextual stressors are…

  16. Physics Matters: An Introduction to Conceptual Physics, Activity Book

    NASA Astrophysics Data System (ADS)

    Trefil, James; Hazen, Robert M.

    2004-02-01

    From amusement park rides to critical environmental issues such as energy generation-physics affects almost every aspect of our world. In PHYSICS MATTERS, James Trefil and Robert Hazen examine the fundamental physics principles at work behind the many practical applications that fuel our society and individual lives. Their goal is to promote a deeper understanding of how the great ideas of physics connect to form a much larger understanding of the universe in which we live. Highlights Helps readers build a general knowledge of key ideas in physics and their connection to technology and other areas of science. Promotes an appreciation of what science is, how scientific knowledge is developed, and how it differs from other intellectual activities. Examines modern technologies, including GPS, the Internet, and information technologies, as well as medical technologies, such as MRI, PET scans, CAT scans, and radioisotope tracers. Explores key issues facing the world today, such as global warning, nuclear waste, and government funding for research.

  17. Critical issues in sensor science to aid food and water safety.

    PubMed

    Farahi, R H; Passian, A; Tetard, L; Thundat, T

    2012-06-26

    The stability of food and water supplies is widely recognized as a global issue of fundamental importance. Sensor development for food and water safety by nonconventional assays continues to overcome technological challenges. The delicate balance between attaining adequate limits of detection, chemical fingerprinting of the target species, dealing with the complex food matrix, and operating in difficult environments are still the focus of current efforts. While the traditional pursuit of robust recognition methods remains important, emerging engineered nanomaterials and nanotechnology promise better sensor performance but also bring about new challenges. Both advanced receptor-based sensors and emerging non-receptor-based physical sensors are evaluated for their critical challenges toward out-of-laboratory applications.

  18. Promoting Parent and Child Physical Activity Together: Elicitation of Potential Intervention Targets and Preferences.

    PubMed

    Rhodes, Ryan E; Lim, Clarise

    2018-02-01

    Promoting physical activities that involve both parents and their children would be very useful to the improved health and well-being of families, yet coactivity interventions have been particularly unsuccessful in past research. The purpose of this study was to elicit the salient parental beliefs about coactivity framed through theory of planned behavior in order to inform future intervention content. A representative sample of Canadian parents ( N = 483) with children aged 6 to 14 years completed belief elicitation measures of theory of planned behavior, as well as coactivity and program preferences. Analyses included content theming by physical activity belief and preference through tallies of the percentages of parents endorsing each belief. Exploratory analyses of differences in endorsed themes were conducted by parent (mother, father), age of child (6-10 years, 11-14 years), and sex of the child. The results showed that behavioral beliefs about health, interpersonal and educational/learning opportunities and control beliefs about lack of time, various incompatible parent/child factors, parental health, and bad weather were dominant themes. Most of these themes did not vary in endorsement by parent and child characteristics. By contrast, preferences for various activities varied by parent and child characteristics, yet parents overwhelmingly desired the activities to be outdoors, close to home, after work, and originally delivered from community health professionals via Internet or face-to face means. Overall, the findings provide several considerations for specific targets to improve future physical activity intervention approaches among parents and their children.

  19. [Psychological issues in manned spaceflight].

    PubMed

    Zhang, Q J; Bai, Y Q

    1999-04-01

    As the duration of manned spaceflight becomes longer and as crews become more heterogeneous, psychological and interpersonal factors will be more important in affecting the safety of crew and flight mission. In space environment there are four types of stressors: physical, physiological, psychological and interpersonal. Psychological issues include "Asthenia", alteration in time sense, transcendent experiences, sleep problem, career motivation, psychosomatic symptoms and psychiatric issues. Interpersonal issues include interpersonal tension, interpersonal relationships decreased cohesiveness and deprivation, displacement [correction of dispiacement] of anger to outside personnel over time.

  20. Nuclear physics in particle therapy: a review

    NASA Astrophysics Data System (ADS)

    Durante, Marco; Paganetti, Harald

    2016-09-01

    Charged particle therapy has been largely driven and influenced by nuclear physics. The increase in energy deposition density along the ion path in the body allows reducing the dose to normal tissues during radiotherapy compared to photons. Clinical results of particle therapy support the physical rationale for this treatment, but the method remains controversial because of the high cost and of the lack of comparative clinical trials proving the benefit compared to x-rays. Research in applied nuclear physics, including nuclear interactions, dosimetry, image guidance, range verification, novel accelerators and beam delivery technologies, can significantly improve the clinical outcome in particle therapy. Measurements of fragmentation cross-sections, including those for the production of positron-emitting fragments, and attenuation curves are needed for tuning Monte Carlo codes, whose use in clinical environments is rapidly increasing thanks to fast calculation methods. Existing cross sections and codes are indeed not very accurate in the energy and target regions of interest for particle therapy. These measurements are especially urgent for new ions to be used in therapy, such as helium. Furthermore, nuclear physics hardware developments are frequently finding applications in ion therapy due to similar requirements concerning sensors and real-time data processing. In this review we will briefly describe the physics bases, and concentrate on the open issues.

  1. Nuclear physics in particle therapy: a review.

    PubMed

    Durante, Marco; Paganetti, Harald

    2016-09-01

    Charged particle therapy has been largely driven and influenced by nuclear physics. The increase in energy deposition density along the ion path in the body allows reducing the dose to normal tissues during radiotherapy compared to photons. Clinical results of particle therapy support the physical rationale for this treatment, but the method remains controversial because of the high cost and of the lack of comparative clinical trials proving the benefit compared to x-rays. Research in applied nuclear physics, including nuclear interactions, dosimetry, image guidance, range verification, novel accelerators and beam delivery technologies, can significantly improve the clinical outcome in particle therapy. Measurements of fragmentation cross-sections, including those for the production of positron-emitting fragments, and attenuation curves are needed for tuning Monte Carlo codes, whose use in clinical environments is rapidly increasing thanks to fast calculation methods. Existing cross sections and codes are indeed not very accurate in the energy and target regions of interest for particle therapy. These measurements are especially urgent for new ions to be used in therapy, such as helium. Furthermore, nuclear physics hardware developments are frequently finding applications in ion therapy due to similar requirements concerning sensors and real-time data processing. In this review we will briefly describe the physics bases, and concentrate on the open issues.

  2. Magnetic microgels for drug targeting applications: Physical-chemical properties and cytotoxicity evaluation

    NASA Astrophysics Data System (ADS)

    Turcu, Rodica; Craciunescu, Izabell; Garamus, Vasil M.; Janko, Christina; Lyer, Stefan; Tietze, Rainer; Alexiou, Christoph; Vekas, Ladislau

    2015-04-01

    Magnetoresponsive microgels with high saturation magnetization values have been obtained by a strategy based on the miniemulsion method using high colloidal stability organic carrier ferrofluid as primary material. Hydrophobic nanoparticles Fe3O4/oleic acid are densely packed into well-defined spherical nanoparticle clusters coated with polymers with sizes in the range 40-350 nm. Physical-chemical characteristics of magnetic microgels were investigated by TEM, SAXS, XPS and VSM measurements with the focus on the structure-properties relationship. The impact of magnetic microgels loaded with anticancer drug mitoxantrone (MTO) on the non-adherent human T cell leukemia line Jurkat was investigated in multiparameter flow cytometry. We showed that both MTO and microgel-loaded MTO penetrate into cells and both induce apoptosis and later secondary necrosis in a time- and dose dependent manner. In contrast, microgels without MTO are not cytotoxic in the corresponding concentrations. Our results show that MTO-loaded microgels are promising structures for application in magnetic drug targeting.

  3. Highly multiplexed targeted DNA sequencing from single nuclei.

    PubMed

    Leung, Marco L; Wang, Yong; Kim, Charissa; Gao, Ruli; Jiang, Jerry; Sei, Emi; Navin, Nicholas E

    2016-02-01

    Single-cell DNA sequencing methods are challenged by poor physical coverage, high technical error rates and low throughput. To address these issues, we developed a single-cell DNA sequencing protocol that combines flow-sorting of single nuclei, time-limited multiple-displacement amplification (MDA), low-input library preparation, DNA barcoding, targeted capture and next-generation sequencing (NGS). This approach represents a major improvement over our previous single nucleus sequencing (SNS) Nature Protocols paper in terms of generating higher-coverage data (>90%), thereby enabling the detection of genome-wide variants in single mammalian cells at base-pair resolution. Furthermore, by pooling 48-96 single-cell libraries together for targeted capture, this approach can be used to sequence many single-cell libraries in parallel in a single reaction. This protocol greatly reduces the cost of single-cell DNA sequencing, and it can be completed in 5-6 d by advanced users. This single-cell DNA sequencing protocol has broad applications for studying rare cells and complex populations in diverse fields of biological research and medicine.

  4. Engaging Middle School Students in Physical Education and Physical Activity Programs

    ERIC Educational Resources Information Center

    Doolittle, Sarah

    2016-01-01

    With school-based physical activity emerging as a public health issue, it is more important than ever to understand what keeps children and adolescents interested and participating in physical education and physical activity. As the research on physical activity patterns indicates, the middle school years may be a watershed moment in the lives of…

  5. Branch target buffer design and optimization

    NASA Technical Reports Server (NTRS)

    Perleberg, Chris H.; Smith, Alan J.

    1993-01-01

    Consideration is given to two major issues in the design of branch target buffers (BTBs), with the goal of achieving maximum performance for a given number of bits allocated to the BTB design. The first issue is BTB management; the second is what information to keep in the BTB. A number of solutions to these problems are reviewed, and various optimizations in the design of BTBs are discussed. Design target miss ratios for BTBs are developed, making it possible to estimate the performance of BTBs for real workloads.

  6. Newton in the Big Apple: Issues of equity in physics access and enrollment in New York City public high schools

    NASA Astrophysics Data System (ADS)

    Kelly, Angela Marian

    High school physics is a gateway course for post-secondary study in science, medicine, and engineering, as well as an essential component in the formation of students' scientific literacy. However, physics is widely considered appropriate only for an academic elite. The existence of policies that restrict science opportunities for secondary students results in diminished outcomes in terms of scientific proficiency. Although the national trend in physics enrollment has shown an increase in recent years, the rate of participation is much lower for students in urban schools. This study examines the availability of physics in New York City, and whether access is related to organizational and school-level variables. The statistical distribution of physics students throughout the city is compiled and analyzed. High schools that successfully offer physics are compared with those that do not. Other factors are explored to determine their relationship to physics access, such as the presence of science magnet schools, the availability of Advanced Placement Physics and Non-Regents Physics, the science curricular sequence, and teacher certification. The results show that physics is not widely available to students in New York City, with 55% of high schools simply not offering the subject. Only 27% of schools with fewer than 600 students offer physics. The science magnet schools enroll a significant proportion of physics students when compared with larger, economically depressed neighborhood schools. The causes of these disparities are complex, and the implications serious for those students who do not have equal access to physics. The implications of these findings are important. By highlighting descriptive variables, as well as statistical evidence of systemic discrimination and inequities, urban districts may formulate effective models for the promotion of physics study. School policies and structures need to target better rates of physics participation among all students

  7. Introduction to Focus Issue: nonlinear and stochastic physics in biology.

    PubMed

    Bahar, Sonya; Neiman, Alexander B; Jung, Peter; Kurths, Jürgen; Schimansky-Geier, Lutz; Showalter, Kenneth

    2011-12-01

    Frank Moss was a leading figure in the study of nonlinear and stochastic processes in biological systems. His work, particularly in the area of stochastic resonance, has been highly influential to the interdisciplinary scientific community. This Focus Issue pays tribute to Moss with articles that describe the most recent advances in the field he helped to create. In this Introduction, we review Moss's seminal scientific contributions and introduce the articles that make up this Focus Issue.

  8. Racial and Gender Issues with Physics in the Pacific Region

    NASA Astrophysics Data System (ADS)

    Aung, Than; Singh, Awnesh; Prasad, Uma

    2011-09-01

    This paper examines the state of physics teaching and learning in the Pacific Island nations. How have things changed in teaching physics? We believe that some of the goals and many of the challenges faced today have changed very little over the years. This paper is purely based upon the authors' experiences in teaching physics at the first-year level at the University of the South Pacific (USP). USP is a typical medium-sized teaching and research university as compared to universities internationally. In the Pacific, it is the biggest university and is effectively serving the 12 Pacific Island nations. Consequently, the findings described here should represent the overall situation for the Pacific region. Perhaps some of our results will resonate with readers in other locations as well. Worldwide, university students often find studying physics to be very challenging, and only a small fraction of them choose physics as a major for their degree or as a career. Students at USP are not an exception, and here we describe the severity of the problem.

  9. Introduction: Cardiovascular physics

    NASA Astrophysics Data System (ADS)

    Wessel, Niels; Kurths, Jürgen; Ditto, William; Bauernschmitt, Robert

    2007-03-01

    The number of patients suffering from cardiovascular diseases increases unproportionally high with the increase of the human population and aging, leading to very high expenses in the public health system. Therefore, the challenge of cardiovascular physics is to develop high-sophisticated methods which are able to, on the one hand, supplement and replace expensive medical devices and, on the other hand, improve the medical diagnostics with decreasing the patient's risk. Cardiovascular physics-which interconnects medicine, physics, biology, engineering, and mathematics-is based on interdisciplinary collaboration of specialists from the above scientific fields and attempts to gain deeper insights into pathophysiology and treatment options. This paper summarizes advances in cardiovascular physics with emphasis on a workshop held in Bad Honnef, Germany, in May 2005. The meeting attracted an interdisciplinary audience and led to a number of papers covering the main research fields of cardiovascular physics, including data analysis, modeling, and medical application. The variety of problems addressed by this issue underlines the complexity of the cardiovascular system. It could be demonstrated in this Focus Issue, that data analyses and modeling methods from cardiovascular physics have the ability to lead to significant improvements in different medical fields. Consequently, this Focus Issue of Chaos is a status report that may invite all interested readers to join the community and find competent discussion and cooperation partners.

  10. Using Socioscientific Issues in Primary Classrooms

    ERIC Educational Resources Information Center

    Dolan, Thomas J.; Nichols, Bryan H.; Zeidler, Dana L.

    2009-01-01

    In this article, we provide three examples of the use of socioscientific issues (SSI) in a 5th-grade classroom. Taken from Earth science (beach sand replacement), life science (the Canadian seal hunt), and physical science (speed limits), the examples show how teachers can embed scientific content in controversial social issues that engage younger…

  11. Physical Education--Dead, Quiescent, or Undergoing Modification?

    ERIC Educational Resources Information Center

    Zeigler, Earle F.

    1982-01-01

    The issues surrounding the status of physical education are explored. Those working in the field of physical education are said to have inferiority complexes and feelings of embarrassment about their chosen profession. A list of 10 recent developments focuses on issues which confront the physical education profession. (JN)

  12. Special issue on the spectroscopy of transient plasmas

    NASA Astrophysics Data System (ADS)

    Bailey, James; Hoarty, David; Mancini, Roberto; Yoneda, Hitoki

    2015-01-01

    Experimental and theoretical papers are invited for a special issue of Journal of Physics B: Atomic, Molecular and Optical Physics on Spectroscopy of Transient Plasmas, covering plasma conditions produced by pulsed laboratory sources including for example, short and long pulse lasers; pulsed power devices; FELs; XFELs and ion beams. The full range of plasma spectroscopy from the optical range up to high energy bremsstrahlung radiation will be covered. The deadline for submitting to this special issue is 1 March 2015. (Expected web publication: autumn 2015). Late submissions will be considered for the journal, but may not be included in the special issue. All submitted articles will be fully refereed to the journal's usual high standards. Upon publication, the issue will be widely promoted to the atomic, molecular and optical physics community, ensuring that your work receives maximum visibility. Articles should be submitted at http://mc04.manuscriptcentral.com/jphysb-iop. Should you have any questions regarding the preparation of manuscripts or the suitability of your work for this Issue, please do not hesitate to contact the J. Phys. B: At. Mol. Opt. Editorial team (jphysb@iop.org). We look forward to hearing from you and hope that we can welcome you as a contributing author.

  13. Sensor planning for moving targets

    NASA Astrophysics Data System (ADS)

    Musman, Scott A.; Lehner, Paul; Elsaesser, Chris

    1994-10-01

    Planning a search for moving ground targets is difficult for humans and computationally intractable. This paper describes a technique to solve such problems. The main idea is to combine probability of detection assessments with computational search heuristics to generate sensor plans which approximately maximize either the probability of detection or a user- specified knowledge function (e.g., determining the target's probable destination; locating the enemy tanks). In contrast to super computer-based moving target search planning, our technique has been implemented using workstation technology. The data structures generated by sensor planning can be used to evaluate sensor reports during plan execution. Our system revises its objective function with each sensor report, allowing the user to assess both the current situation as well as the expected value of future information. This capability is particularly useful in situations involving a high rate of sensor reporting, helping the user focus his attention on sensors reports most pertinent to current needs. Our planning approach is implemented in a three layer architecture. The layers are: mobility analysis, followed by sensor coverage analysis, and concluding with sensor plan analysis. It is possible using these layers to describe the physical, spatial, and temporal characteristics of a scenario in the first two layers, and customize the final analysis to specific intelligence objectives. The architecture also allows a user to customize operational parameters in each of the three major components of the system. As examples of these performance options, we briefly describe the mobility analysis and discuss issues affecting sensor plan analysis.

  14. Conference for Undergraduate Women in Physics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bonnie Fleming

    2009-04-01

    The Yale Conference for Undergraduate Women in Physics was held on January 18th and 19th, 2008. The conference, targeted toward undergraduates in the Northeast, was a huge success. It was well attended by both a slate of impressive speakers including Janet Conrad, Mildred Dresselhaus, Elsa Garmire, Howard Georgi, Liz Rhodes, Meg Urry and Wendy Zhang, and many interested attendees. Talks were on current research, about issues for women in physics, and on the application process for graduate school. There was also a career panel, student talks, and a student poster session. The conference ran concurrently with the third annual conferencemore » at USC, as well as a first annual conference at the University of Michigan. Our purpose in creating this conference was to provide a supportive atmosphere for young physicists to connect with peers and with successful women in the field. We hope that from this conference, attendees have become confident and knowledgeable about applying to graduate school and be further inspired to pursue a career in physics. The following describes the conference program, participation and impact, logistics of running the conference and plans for the future.« less

  15. Parametric bicubic spline and CAD tools for complex targets shape modelling in physical optics radar cross section prediction

    NASA Astrophysics Data System (ADS)

    Delogu, A.; Furini, F.

    1991-09-01

    Increasing interest in radar cross section (RCS) reduction is placing new demands on theoretical, computation, and graphic techniques for calculating scattering properties of complex targets. In particular, computer codes capable of predicting the RCS of an entire aircraft at high frequency and of achieving RCS control with modest structural changes, are becoming of paramount importance in stealth design. A computer code, evaluating the RCS of arbitrary shaped metallic objects that are computer aided design (CAD) generated, and its validation with measurements carried out using ALENIA RCS test facilities are presented. The code, based on the physical optics method, is characterized by an efficient integration algorithm with error control, in order to contain the computer time within acceptable limits, and by an accurate parametric representation of the target surface in terms of bicubic splines.

  16. Targeted alpha therapy using Radium-223: From physics to biological effects.

    PubMed

    Marques, I A; Neves, A R; Abrantes, A M; Pires, A S; Tavares-da-Silva, E; Figueiredo, A; Botelho, M F

    2018-05-25

    With the advance of the use of ionizing radiation in therapy, targeted alpha therapy (TAT) has assumed an important role around the world. This kind of therapy can potentially reduce side effects caused by radiation in normal tissues and increased destructive radiobiological effects in tumor cells. However, in many countries, the use of this therapy is still in a pioneering phase. Radium-223 ( 223 Ra), an alpha-emitting radionuclide, has been the first of its kind to be approved for the treatment of bone metastasis in metastatic castration-resistant prostate cancer. Nevertheless, the interaction mechanism and the direct effects of this radiopharmaceutical in tumor cells are not fully understood neither characterized at a molecular level. In fact, the ways how TAT is linked to radiobiological effects in cancer is not yet revised. Therefore, this review introduces some physical properties of TAT that leads to biological effects and links this information to the hallmarks of cancer. The authors also collected the studies developed with 223 Ra to correlate with the three categories reviewed - properties of TAT, 5 R's of radiobiology and hallmarks of cancer- and with the promising future to this radiopharmaceutical. Copyright © 2018 Elsevier Ltd. All rights reserved.

  17. A systematic review of universal campaigns targeting child physical abuse prevention

    PubMed Central

    Poole, Mary Kathryn; Seal, David W.; Taylor, Catherine A.

    2014-01-01

    The purpose of this review was to better understand the impact of universal campaign interventions with a media component aimed at preventing child physical abuse (CPA). The review included 17 studies featuring 15 campaigns conducted from 1989 to 2011 in five countries. Seven studies used experimental designs, but most were quasi-experimental. CPA incidence was assessed in only three studies and decreased significantly in two. Studies also found significant reductions in relevant outcomes such as dysfunctional parenting, child problem behaviors and parental anger as well as increases in parental self-efficacy and knowledge of concepts and actions relevant to preventing child abuse. The following risk factors were most frequently targeted in campaigns: lack of knowledge regarding positive parenting techniques, parental impulsivity, the stigma of asking for help, inadequate social support and inappropriate expectations for a child’s developmental stage. The evidence base for universal campaigns designed to prevent CPA remains inconclusive due to the limited availability of rigorous evaluations; however, Triple-P is a notable exception. Given the potential for such interventions to shift population norms relevant to CPA and reduce rates of CPA, there is a need to further develop and rigorously evaluate such campaigns. PMID:24711483

  18. Special issue on compact x-ray sources

    NASA Astrophysics Data System (ADS)

    Hooker, Simon; Midorikawa, Katsumi; Rosenzweig, James

    2014-04-01

    Journal of Physics B: Atomic, Molecular and Optical Physics is delighted to announce a forthcoming special issue on compact x-ray sources, to appear in the winter of 2014, and invites you to submit a paper. The potential for high-brilliance x- and gamma-ray sources driven by advanced, compact accelerators has gained increasing attention in recent years. These novel sources—sometimes dubbed 'fifth generation sources'—will build on the revolutionary advance of the x-ray free-electron laser (FEL). New radiation sources of this type have widespread applications, including in ultra-fast imaging, diagnostic and therapeutic medicine, and studies of matter under extreme conditions. Rapid advances in compact accelerators and in FEL techniques make this an opportune moment to consider the opportunities which could be realized by bringing these two fields together. Further, the successful development of compact radiation sources driven by compact accelerators will be a significant milestone on the road to the development of high-gradient colliders able to operate at the frontiers of particle physics. Thus the time is right to publish a peer-reviewed collection of contributions concerning the state-of-the-art in: advanced and novel acceleration techniques; sophisticated physics at the frontier of FELs; and the underlying and enabling techniques of high brightness electron beam physics. Interdisciplinary research connecting two or more of these fields is also increasingly represented, as exemplified by entirely new concepts such as plasma based electron beam sources, and coherent imaging with fs-class electron beams. We hope that in producing this special edition of Journal of Physics B: Atomic, Molecular and Optical Physics (iopscience.iop.org/0953-4075/) we may help further a challenging mission and ongoing intellectual adventure: the harnessing of newly emergent, compact advanced accelerators to the creation of new, agile light sources with unprecedented capabilities

  19. Preface to the Focus Issue: chaos detection methods and predictability.

    PubMed

    Gottwald, Georg A; Skokos, Charalampos

    2014-06-01

    This Focus Issue presents a collection of papers originating from the workshop Methods of Chaos Detection and Predictability: Theory and Applications held at the Max Planck Institute for the Physics of Complex Systems in Dresden, June 17-21, 2013. The main aim of this interdisciplinary workshop was to review comprehensively the theory and numerical implementation of the existing methods of chaos detection and predictability, as well as to report recent applications of these techniques to different scientific fields. The collection of twelve papers in this Focus Issue represents the wide range of applications, spanning mathematics, physics, astronomy, particle accelerator physics, meteorology and medical research. This Preface surveys the papers of this Issue.

  20. Scalable Methods for Uncertainty Quantification, Data Assimilation and Target Accuracy Assessment for Multi-Physics Advanced Simulation of Light Water Reactors

    NASA Astrophysics Data System (ADS)

    Khuwaileh, Bassam

    High fidelity simulation of nuclear reactors entails large scale applications characterized with high dimensionality and tremendous complexity where various physics models are integrated in the form of coupled models (e.g. neutronic with thermal-hydraulic feedback). Each of the coupled modules represents a high fidelity formulation of the first principles governing the physics of interest. Therefore, new developments in high fidelity multi-physics simulation and the corresponding sensitivity/uncertainty quantification analysis are paramount to the development and competitiveness of reactors achieved through enhanced understanding of the design and safety margins. Accordingly, this dissertation introduces efficient and scalable algorithms for performing efficient Uncertainty Quantification (UQ), Data Assimilation (DA) and Target Accuracy Assessment (TAA) for large scale, multi-physics reactor design and safety problems. This dissertation builds upon previous efforts for adaptive core simulation and reduced order modeling algorithms and extends these efforts towards coupled multi-physics models with feedback. The core idea is to recast the reactor physics analysis in terms of reduced order models. This can be achieved via identifying the important/influential degrees of freedom (DoF) via the subspace analysis, such that the required analysis can be recast by considering the important DoF only. In this dissertation, efficient algorithms for lower dimensional subspace construction have been developed for single physics and multi-physics applications with feedback. Then the reduced subspace is used to solve realistic, large scale forward (UQ) and inverse problems (DA and TAA). Once the elite set of DoF is determined, the uncertainty/sensitivity/target accuracy assessment and data assimilation analysis can be performed accurately and efficiently for large scale, high dimensional multi-physics nuclear engineering applications. Hence, in this work a Karhunen-Loeve (KL

  1. Liquid Biopsy and Therapeutic Targets: Present and Future Issues in Thoracic Oncology

    PubMed Central

    Hofman, Paul

    2017-01-01

    The practice of liquid biopsy (LB) has revolutionized the care of patients with metastatic lung cancer. Many oncologists now use this approach in daily practice, applying precise procedures for the detection of activating or resistance mutations in EGFR. These tests are performed with plasma DNA and have been approved as companion diagnostic test for patients treated with tyrosine kinase inhibitors. ALK is another important target in lung cancer since it leads to treatment of patients who are positive for a rearrangement in ALK identified with tumor tissue. By analogy with EGFR, LB for detection of genomic alterations in ALK (rearrangements or mutations) has been rapidly adopted in the clinic. However, this promising approach has some limitations and has not yet been disseminated as much as the blood test targeting EGFR. In addition to these two therapeutic targets LB can be used for evaluation of the genomic status of other genes of interest of patients with lung cancer (ROS1, RET, NTRK MET, BRAF, HER2, etc.). LB can be performed to evaluate a specific target or for a more or less complex panel of genes. Considering the number of potential targets for clinical trials, techniques of next-generation sequencing of circulating DNA are on the rise. This review will provide an update on the contribution of LB to care of patients with metastatic lung cancer, including the present limits of this approach, and will consider certain perspectives. PMID:29125548

  2. Physics issues in diffraction limited storage ring design

    NASA Astrophysics Data System (ADS)

    Fan, Wei; Bai, ZhengHe; Gao, WeiWei; Feng, GuangYao; Li, WeiMin; Wang, Lin; He, DuoHui

    2012-05-01

    Diffraction limited electron storage ring is considered a promising candidate for future light sources, whose main characteristics are higher brilliance, better transverse coherence and better stability. The challenge of diffraction limited storage ring design is how to achieve the ultra low beam emittance with acceptable nonlinear performance. Effective linear and nonlinear parameter optimization methods based on Artificial Intelligence were developed for the storage ring physical design. As an example of application, partial physical design of HALS (Hefei Advanced Light Source), which is a diffraction limited VUV and soft X-ray light source, was introduced. Severe emittance growth due to the Intra Beam Scattering effect, which is the main obstacle to achieve ultra low emittance, was estimated quantitatively and possible cures were discussed. It is inspiring that better performance of diffraction limited storage ring can be achieved in principle with careful parameter optimization.

  3. Teacher candidates' beliefs about including socioscientific issues in physics and chemistry

    NASA Astrophysics Data System (ADS)

    Barrett, Sarah Elizabeth

    Teaching science for social justice involves a deliberate effort to reconstruct society into something more equitable and just. Introducing socioscientific issues (SSI) into science is one strategy toward this end. However, research indicates that SSI are rarely discussed in the physical sciences even though they exist. This may be due to the beliefs of chemistry and physics teachers with respect to what belongs in these subjects. If we wish to begin to influence these beliefs through initial teacher education, it is essential for teacher educators to understand the origins of these beliefs. In this qualitative study 12 teacher candidates were interviewed at 3 points during a 9 month teacher education program: at the beginning of the course (in September), after the first practicum (in November) and after the second practicum (in March). Teacher candidates' beliefs did not change significantly from the beginning of the study to the end. They displayed varying degrees of commitment to including SSI in their teaching. Based on their (a) conception of the ethics of science, (b) goals for science education, (c) idea of the place of ethics in science (education), and (d) beliefs about including SSI, the teacher candidates were divided into four groups. Four archetypes were derived: "Model Scientist/Engineer", "Model Individual", "Model Teacher", and "Model Citizen". Since these groups are archetypes, none of the participants fits into the categories perfectly but individual teacher candidates demonstrated more characteristics of one archetype than others. Only the 3 Model Citizens were committed to including SSI in their teaching while the others placed the priority on preparing students for the next level of schooling. A model was developed to serve as a microgeneology of teacher candidates' beliefs about including SSI in their teaching. It traced their beliefs from (a) life experiences to (b) conception of ethics and nature of science to (c) goals for science

  4. Targeted physical activity messages for parents of children with disabilities: A qualitative investigation of parents' informational needs and preferences.

    PubMed

    Bassett-Gunter, R L; Ruscitti, R J; Latimer-Cheung, A E; Fraser-Thomas, J L

    2017-05-01

    Physical activity (PA) has myriad benefits for children with disabilities (CWD). Information and messaging campaigns can promote PA among CWD. The overall purpose of the study was to gain an understanding of the development of PA information and messages targeting parents of CWD. The specific objectives were to identify parents' preferences regarding PA information and messaging content and preferred methods and sources of communication. Focus groups were conducted with parents of CWD (N=28). Qualitative data were collected and transcribed. Inductive content analyses were employed to identify key themes. Three key thematic areas were identified: 1) Preferred content (e.g., targeted information, self-regulatory strategies, inclusive images), 2) Challenges (e.g., lack of information and language clarity), 3) Preferred sources (e.g., other parents, reliable organizations, central information hub). Parents' needs and preferences regarding PA information could be incorporated into campaigns to enhance parent PA support and PA among CWD. Stakeholders (e.g., PA organizations, programs and practitioners) can employ these strategies in campaigns and resources targeting parents of CWD. Research is necessary to empirically develop and evaluate PA information and messaging campaigns targeting parents of CWD. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. FOREWORD: Special issue on electrical charge

    NASA Astrophysics Data System (ADS)

    Gillies, George T.

    2004-10-01

    This special issue on the physics and metrology of electrical charge attempts to provide the interested reader with an overview of the ways in which this fundamental property of matter has been studied and measured, both historically and in present times. Few topics in introductory physics and electrical engineering courses receive as much attention as does the nature and behaviour of electrical charge, and experimental tests of Coulomb’s law are a staple of such curricula. The manipulation of electrical charge, even down to the level of single electrons, constitutes the currency of electrical metrology, while the effects of parasitic forces arising from spurious charges are the bane of virtually all who work in the realm of high precision experimentation. Moreover, basic questions about the equality, discreteness and possible fractional sizes of elementary charges lie at the foundation of modern physics on the one hand, while the control of charge carriers within electrical and electronic devices forms the core of essentially all of modern technology, on the other. The theme of the special issue is thus one of reviewing the scientific foundations of charge as a property of matter and as a tool for testing fundamental physical laws. The historical development of both aspects of this theme during the last two centuries has helped form the basis for modern electrical metrology. Therefore, it seemed timely to reassess the field with an eye towards future developments, especially since we find ourselves at the 250th anniversary of the period during which Benjamin Franklin carried out some of the first quantitative electrical measurements, in his colonial laboratory in Pennsylvania. To that end, the special issue contains articles on several aspects of electrical charge that have been the focus of intense study during the past several years. Coulomb’s law is of course central to any discussions in electrical science, and two of the articles provide detailed

  6. Research Trend of Physical Skill Science --Towards Elucidation of Physical Skill--

    NASA Astrophysics Data System (ADS)

    Furukawa, Koichi; Ueno, Ken; Ozaki, Tomonobu; Kamisato, Shihoko; Kawamoto, Ryuji; Shibuya, Koji; Shiratori, Naruhiko; Suwa, Masaki; Soga, Masato; Taki, Hirokazu; Fujinami, Tsutomu; Hori, Satoshi; Motomura, Yoichi; Morita, Souhei

    Physical skills and language skills are both fundamental intelligent abilities of human being. In this paper, we focus our attention to such sophisticated physical skills as playing sports and playing instruments and introduce research activities aiming at elucidating and verbalizing them. This research area has been launched recently. We introduce approaches from physical modeling, measurements and data analysis, cognitive science and human interface. We also discuss such issues as skill acquisition and its support systems. Furthermore, we consider a fundamental issue of individual differences occurring in every application of skill elucidation. Finally we introduce several attempts of skill elucidation in the fields of dancing, manufacturing, playing string instruments, sports science and medical care.

  7. The Brockport Physical Fitness Test Training Manual. [Project Target].

    ERIC Educational Resources Information Center

    Winnick, Joseph P.; Short, Francis X., Ed.

    This training manual presents information on the Brockport Physical Fitness Test (BPFT), a criterion-referenced fitness test for children and adolescents with disabilities. The first chapter of the test training manual includes information dealing with health-related criterion-referenced testing, the interaction between physical activity and…

  8. Performing target specific band reduction using artificial neural networks and assessment of its efficacy using various target detection algorithms

    NASA Astrophysics Data System (ADS)

    Yadav, Deepti; Arora, M. K.; Tiwari, K. C.; Ghosh, J. K.

    2016-04-01

    Hyperspectral imaging is a powerful tool in the field of remote sensing and has been used for many applications like mineral detection, detection of landmines, target detection etc. Major issues in target detection using HSI are spectral variability, noise, small size of the target, huge data dimensions, high computation cost, complex backgrounds etc. Many of the popular detection algorithms do not work for difficult targets like small, camouflaged etc. and may result in high false alarms. Thus, target/background discrimination is a key issue and therefore analyzing target's behaviour in realistic environments is crucial for the accurate interpretation of hyperspectral imagery. Use of standard libraries for studying target's spectral behaviour has limitation that targets are measured in different environmental conditions than application. This study uses the spectral data of the same target which is used during collection of the HSI image. This paper analyze spectrums of targets in a way that each target can be spectrally distinguished from a mixture of spectral data. Artificial neural network (ANN) has been used to identify the spectral range for reducing data and further its efficacy for improving target detection is verified. The results of ANN proposes discriminating band range for targets; these ranges were further used to perform target detection using four popular spectral matching target detection algorithm. Further, the results of algorithms were analyzed using ROC curves to evaluate the effectiveness of the ranges suggested by ANN over full spectrum for detection of desired targets. In addition, comparative assessment of algorithms is also performed using ROC.

  9. Inference for the physical sciences

    PubMed Central

    Jones, Nick S.; Maccarone, Thomas J.

    2013-01-01

    There is a disconnect between developments in modern data analysis and some parts of the physical sciences in which they could find ready use. This introduction, and this issue, provides resources to help experimental researchers access modern data analysis tools and exposure for analysts to extant challenges in physical science. We include a table of resources connecting statistical and physical disciplines and point to appropriate books, journals, videos and articles. We conclude by highlighting the relevance of each of the articles in the associated issue. PMID:23277613

  10. A review of the Fermilab fixed-target program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rameika, R.

    1994-12-01

    All eyes are now on the Fermilab collider program as the intense search for the top quark continues. Nevertheless, Fermilab`s long tradition of operating a strong, diverse physics program depends not only on collider physics but also on effective use of the facilities the Laboratory was founded on, the fixed-target beamlines. In this talk the author presents highlights of the Fermilab fixed-target program from its (not too distant) past, (soon to be) present, and (hopefully, not too distant) future program. The author concentrates on those experiments which are unique to the fixed-target program, in particular hadron structure measurements which usemore » the varied beams and targets available in this mode and the physics results from kaon, hyperon and high statistics charm experiments which are not easily accessible in high p{sub T} hadron collider detectors.« less

  11. Women with disabilities' experience with physical and sexual abuse: review of the literature and implications for the field.

    PubMed

    Plummer, Sara-Beth; Findley, Patricia A

    2012-01-01

    While studies suggest that the rate of abuse of women with disabilities is similar or higher compared to the general population, there continues to be a lack of attention to this issue. Women with disabilities are at particularly high risk of abuse, both through typical forms of violence (physical, sexual, and emotional) and those that target one's disability. In an effort to highlight the need for increased attention to this issue, this article reviews the current peer-reviewed research in this field. The authors outline recommendations for future research goals and provide implications for research, practice, and policy.

  12. Mercury target R&D for the Oak Ridge spallation neutron source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Haines, J.R.; DiStefano, J.; Farrell, K.

    1996-06-01

    The conceptual design for the Oak Ridge Spallation Neutron Source (ORSNS) incorporates liquid mercury as its reference target material. A flowing liquid target was selected mainly because of the increased power handling capability possible with the convective transport process. The major reasons for choosing mercury as the liquid target material are because it: (1) is a liquid at room temperature, (2) has good heat transport properties, and (3) has a high atomic number and mass density resulting in high neutron yield and source brightness. Since liquid targets are not widely utilized in presently operating accelerator targets and because of themore » challenges posed by the intense, pulsed thermal energy deposition ({approximately}20-100 kJ deposited during each 1-10 {mu}s pulse), considerable R&D is planned for the mercury target concept. The key feasibility issue that will be addressed in early R&D efforts are the effects of the thermal shock environment, which will include development and testing of approaches to mitigate these effects. Materials compatiblity and ES&H issues associated with the use of liquid mercury are also of major importance in early R&D efforts. A brief description of the mercury target design concept, results of initial evaluations of its performance characteristics, identification of its critical issues, and an outline of the R&D program aimed at addressing these issues will be presented.« less

  13. Physical Activity at Daycare: Issues, Challenges and Perspectives

    ERIC Educational Resources Information Center

    van Zandvoort, Melissa; Tucker, Patricia; Irwin, Jennifer D.; Burke, Shauna M.

    2010-01-01

    This study sought to examine London, Ontario-based childcare providers' perspectives of the barriers and facilitators to physical activity participation among preschoolers (i.e. children aged 2.5-5 years) attending daycare. A heterogeneous sample of childcare providers (n = 54; response rate 47%) working at public daycare facilities in London,…

  14. Targeted Optimization of Quasi-Symmetric Stellarators

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hegna, Chris C.; Anderson, D. T.; Talmadge, J. N.

    2016-10-06

    The proposed research focuses on targeted areas of plasma physics dedicated to improving the stellarator concept. Research was pursued in the technical areas of edge/divertor physics in 3D configurations, magnetic island physics in stellarators, the role of 3D shaping on microinstabilities and turbulent transport and energetic ion confinement in stellarators.

  15. A systematic review of universal campaigns targeting child physical abuse prevention.

    PubMed

    Poole, Mary Kathryn; Seal, David W; Taylor, Catherine A

    2014-06-01

    The purpose of this review was to better understand the impact of universal campaign interventions with a media component aimed at preventing child physical abuse (CPA). The review included 17 studies featuring 15 campaigns conducted from 1989 to 2011 in five countries. Seven studies used experimental designs, but most were quasi-experimental. CPA incidence was assessed in only three studies and decreased significantly in two. Studies also found significant reductions in relevant outcomes such as dysfunctional parenting, child problem behaviors and parental anger as well as increases in parental self-efficacy and knowledge of concepts and actions relevant to preventing child abuse. The following risk factors were most frequently targeted in campaigns: lack of knowledge regarding positive parenting techniques, parental impulsivity, the stigma of asking for help, inadequate social support and inappropriate expectations for a child's developmental stage. The evidence base for universal campaigns designed to prevent CPA remains inconclusive due to the limited availability of rigorous evaluations; however, Triple-P is a notable exception. Given the potential for such interventions to shift population norms relevant to CPA and reduce rates of CPA, there is a need to further develop and rigorously evaluate such campaigns. © The Author 2014. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  16. Different Names, Same Issue.

    ERIC Educational Resources Information Center

    Bjorkqvist, Kaj

    2001-01-01

    Discusses the origin of the categories of relational, social, and indirect aggression in Finnish studies on the nature of female aggression, arguing that all three names represent the same issue. Considers early research into the developmental origins of indirect aggression, and the role of physical, verbal, and indirect aggression as three…

  17. Considerations for planning and conducting clinic-based research in physical therapy.

    PubMed

    Fitzgerald, G K; Delitto, A

    2001-08-01

    There is growing demand to increase the volume of clinic-based research in physical therapy. Special considerations, unique to the planning and conduct of clinic-based research, need to be addressed to increase the likelihood that these studies will be completed successfully. The purposes of this perspective are to discuss factors affecting clinic-based research and to offer suggestions for addressing these problems when designing and conducting research studies in a clinical setting. This perspective discusses issues such as patient management, determining the availability of target patient populations, acquiring support from physical therapists and physicians, reporting and managing research-related injury or illness, and modifying or terminating projects. Some of the points made in this perspective are illustrated using examples from the authors' experiences in conducting clinical research.

  18. Designing an Active Target Test Projection Chamber

    NASA Astrophysics Data System (ADS)

    Koci, James; Tan Ahn Collaboration, Dr.; Nicolas Dixneuf Collaboration

    2015-10-01

    The development of instrumentation in nuclear physics is crucial for advancing our ability to measure the properties of exotic nuclei. One limitation of the use of exotic nuclei in experiment is their very low production intensities. Recently, detectors, called active-target dectectors, have been developed to address this issue. Active-target detectors use a gas medium to image charged-particle tracks that are emitted in nuclear reactions. Last semester, I designed a vacuum chamber to be used in developing Micro-Pattern Gas detectors that will upgrade the capabilities of an active-target detector called the Prototype AT-TPC. With the exterior of the chamber complete, I have now been using an electric field modeling program, Garfield, developed by CERN to design a field cage to be placed within the vacuum chamber. The field cage will be a box-like apparatus consisting of two parallel metal plates connected with a resistor chain and attached to wires wrapped between them. The cage will provide a uniform electric field within the chamber to drift electrons from nuclear reactions down to the detector in the bottom of the chamber. These signals are then amplified by a proportional counter, and the data is sent to a computer. For the long term, we would like to incorporate a Micro-Pattern Gas Detectors in the interior of the chamber and eventually use the AT-TPC to examine various nuclei. Dr. Ahn is my advising professor.

  19. UNICEF News, Issue 73: Education.

    ERIC Educational Resources Information Center

    United Nations Children's Fund, New York, NY.

    This quarterly publication from UNICEF, announced here on a one time basis, reviews the Fund's activities in health, education, and nutrition for the children of developing countries. The following is a sample of articles from this issue devoted to education: "New Targets" discusses recommendations for emphasizing minimum education,…

  20. Physics Criteria for a Subscale Plasma Liner Experiment

    DOE PAGES

    Hsu, Scott C.; Thio, Yong C. Francis

    2018-02-02

    Spherically imploding plasma liners, formed by merging hypersonic plasma jets, are a proposed standoff driver to compress magnetized target plasmas to fusion conditions (Hsu et al. in IEEE Trans Plasma Sci 40:1287, 2012). Here, in this paper, the parameter space and physics criteria are identified for a subscale, plasma-liner-formation experiment to provide data, e.g., on liner ram-pressure scaling and uniformity, that are relevant for addressing scientific issues of full-scale plasma liners required to achieve fusion conditions. Lastly, based on these criteria, we quantitatively estimate the minimum liner kinetic energy and mass needed, which informed the design of a subscale plasmamore » liner experiment now under development.« less

  1. Physics Criteria for a Subscale Plasma Liner Experiment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hsu, Scott C.; Thio, Yong C. Francis

    Spherically imploding plasma liners, formed by merging hypersonic plasma jets, are a proposed standoff driver to compress magnetized target plasmas to fusion conditions (Hsu et al. in IEEE Trans Plasma Sci 40:1287, 2012). Here, in this paper, the parameter space and physics criteria are identified for a subscale, plasma-liner-formation experiment to provide data, e.g., on liner ram-pressure scaling and uniformity, that are relevant for addressing scientific issues of full-scale plasma liners required to achieve fusion conditions. Lastly, based on these criteria, we quantitatively estimate the minimum liner kinetic energy and mass needed, which informed the design of a subscale plasmamore » liner experiment now under development.« less

  2. The transformation of targeted killing and international order

    PubMed Central

    Senn, Martin; Troy, Jodok

    2017-01-01

    ABSTRACT This article introduces the special issue’s question of whether and how the current transformation of targeted killing is transforming the global international order and provides the conceptual ground for the individual contributions to the special issue. It develops a two-dimensional concept of political order and introduces a theoretical framework that conceives the maintenance and transformation of international order as a dynamic interplay between its behavioral dimension in the form of violence and discursive processes and its institutional dimension in the form of ideas, norms, and rules. The article also conceptualizes targeted killing and introduces a typology of targeted-killing acts on the basis of their legal and moral legitimacy. Building on this conceptual groundwork, the article takes stock of the current transformation of targeted killing and summarizes the individual contributions to this special issue. PMID:29097903

  3. Quantum physics with non-Hermitian operators Quantum physics with non-Hermitian operators

    NASA Astrophysics Data System (ADS)

    Bender, Carl; Fring, Andreas; Günther, Uwe; Jones, Hugh

    2012-11-01

    The main motivation behind the call for this special issue was to gather recent results, developments and open problems in quantum physics with non-Hermitian operators. There have been previous special issues in this journal [1, 2] and elsewhere on this subject. The intention of this issue is to reflect the current state of this rapidly-developing field. It has therefore been open to all contributions containing new results on non-Hermitian theories that are explicitly PT-symmetric and/or pseudo-Hermitian or quasi-Hermitian. In the last decade these types of systems have proved to be viable self-consistent physical theories with well defined unitary time-evolution and real spectra. As the large number of responses demonstrates, this is a rapidly evolving field of research. A consensus has been reached regarding most of the fundamental problems, and the general ideas and techniques are now readily being employed in many areas of physics. Nonetheless, this issue still contains some treatments of a more general nature regarding the spectral analysis of these models, in particular, the physics of the exceptional points, the breaking of the PT-symmetry, an interpretation of negative energies and the consistent implementation of the WKB analysis. This issue also contains a treatment of a scattering theory associated with these types of systems, weak measurements, coherent states, decoherence, unbounded metric operators and the inclusion of domain issues to obtain well defined self-adjoint theories. Contributions in the form of applications of the general ideas include: studies of classical shock-waves and tunnelling, supersymmetric models, spin chain models, models with ring structure, random matrix models, the Pauli equation, the nonlinear Schrödinger equation, quasi-exactly solvable models, integrable models such as the Calogero model, Bose-Einstein condensates, thermodynamics, nonlinear oligomers, quantum catastrophes, the Landau-Zener problem and pseudo

  4. Enhancing and targeting nucleic acid delivery by magnetic force.

    PubMed

    Plank, Christian; Anton, Martina; Rudolph, Carsten; Rosenecker, Joseph; Krötz, Florian

    2003-08-01

    Insufficient contact of inherently highly active nucleic acid delivery systems with target cells is a primary reason for their often observed limited efficacy. Physical methods of targeting can overcome this limitation and reduce the risk of undesired side effects due to non-target site delivery. The authors and others have developed a novel means of physical targeting, exploiting magnetic force acting on nucleic acid vectors associated with magnetic particles in order to mediate the rapid contact of vectors with target cells. Here, the principles of magnetic drug and nucleic acid delivery are reviewed, and the facts and potentials of the technique for research and therapeutic applications are discussed. Magnetically enhanced nucleic acid delivery - magnetofection - is universally applicable to viral and non-viral vectors, is extraordinarily rapid, simple and yields saturation level transfection at low dose in vitro. The method is useful for site-specific vector targeting in vivo. Exploiting the full potential of the technique requires an interdisciplinary research effort in magnetic field physics, magnetic particle chemistry, pharmaceutical formulation and medical application.

  5. Using rapid assessment and response to operationalise physical activity strategic health communication campaigns in Tonga.

    PubMed

    Turk, Tahir; Latu, Netina; Cocker-Palu, Elizabeth; Liavaa, Villiami; Vivili, Paul; Gloede, Sara; Simons, Allison

    2013-04-01

    The aim of the present study was to identify stakeholder and program beneficiary needs and wants in relation to a netball communication strategy in Tonga. In addition, the study aimed to more clearly identify audience segments for targeting of communication campaigns and to identify any barriers or benefits to engaging in the physical activity program. A rapid assessment and response (RAR) methodology was used. The elicitation research encompassed qualitative fieldwork approaches, including semistructured interviews with key informants and focus group discussions with program beneficiaries. Desk research of secondary data sources supported in-field findings. A number of potential barriers to behavioural compliance existed, including cultural factors, gender discrimination, socioeconomic factors, stigmatising attitudes, the threat of domestic violence, infrastructure and training issues. Factors contributing to participation in physical activity included the fun and social aspects of the sport, incentives (including career opportunities, highlighting the health benefits of the activity and the provision of religious and cultural sanctions by local leaders towards the increased physical activity of women. The consultative approach of RAR provided a more in-depth understanding of the need for greater levels of physical activity and opportunities for engagement by all stakeholders. The approach facilitated opportunities for the proposed health behaviours to be realised through the communication strategy. Essential insights for the strategy design were identified from key informants, as well as ensuring future engagement of these stakeholders into the strategy. So what? The expanded use of RAR to inform the design of social marketing interventions is a practical approach to data collection for non-communicable diseases and other health issues in developing countries. The approach allows for the rapid mobilisation of scarce resources for the implementation of more

  6. Physical inactivity as a policy problem: applying a concept from policy analysis to a public health issue.

    PubMed

    Rütten, Alfred; Abu-Omar, Karim; Gelius, Peter; Schow, Diana

    2013-03-07

    Despite the recent rapid development of policies to counteract physical inactivity (PI), only a small number of systematic analyses on the evolution of these policies exists. In this article we analyze how PI, as a public health issue, "translates" into a policy-making issue. First, we discuss why PI has become an increasingly important public health issue during the last two decades. We then follow Guy Peters and conceptualize PI as a "policy problem" that has the potential to be linked to policy instruments and policy impact. Analysis indicates that PI is a policy problem that i) is chronic in nature; ii) involves a high degree of political complexity; iii) can be disaggregated into smaller scales; iv) is addressed through interventions that can be difficult to "sell" to the public when their benefits are not highly divisible; v) cannot be solved by government spending alone; vi) must be addressed through a broad scope of activities; and vii) involves interdependencies among both multiple sectors and levels of government.We conclude that the new perspective on PI proposed in this article might be useful and important for i) describing and mapping policies to counteract PI in different contexts; ii) evaluating whether or not existing policy instruments are appropriate to the policy problem of PI, and iii) explaining the factors and processes that underlie policy development and implementation. More research is warranted in all these areas. In particular, we propose to focus on comparative analyses of how the problem of PI is defined and tackled in different contexts, and on the identification of truly effective policy instruments that are designed to "solve" the PI policy problem.

  7. Manually locating physical and virtual reality objects.

    PubMed

    Chen, Karen B; Kimmel, Ryan A; Bartholomew, Aaron; Ponto, Kevin; Gleicher, Michael L; Radwin, Robert G

    2014-09-01

    In this study, we compared how users locate physical and equivalent three-dimensional images of virtual objects in a cave automatic virtual environment (CAVE) using the hand to examine how human performance (accuracy, time, and approach) is affected by object size, location, and distance. Virtual reality (VR) offers the promise to flexibly simulate arbitrary environments for studying human performance. Previously, VR researchers primarily considered differences between virtual and physical distance estimation rather than reaching for close-up objects. Fourteen participants completed manual targeting tasks that involved reaching for corners on equivalent physical and virtual boxes of three different sizes. Predicted errors were calculated from a geometric model based on user interpupillary distance, eye location, distance from the eyes to the projector screen, and object. Users were 1.64 times less accurate (p < .001) and spent 1.49 times more time (p = .01) targeting virtual versus physical box corners using the hands. Predicted virtual targeting errors were on average 1.53 times (p < .05) greater than the observed errors for farther virtual targets but not significantly different for close-up virtual targets. Target size, location, and distance, in addition to binocular disparity, affected virtual object targeting inaccuracy. Observed virtual box inaccuracy was less than predicted for farther locations, suggesting possible influence of cues other than binocular vision. Human physical interaction with objects in VR for simulation, training, and prototyping involving reaching and manually handling virtual objects in a CAVE are more accurate than predicted when locating farther objects.

  8. In This Issue

    NASA Astrophysics Data System (ADS)

    Warner, Brian D.

    2018-07-01

    This list gives those asteroids in this issue for which physical observations (excluding astrometric only) were made. This includes lightcurves, color index, and H-G determinations, etc. In some cases, no specific results are reported due to a lack of or poor quality data. The page number is for the first page of the paper mentioning the asteroid. EP is the "go to page" value in the electronic version.

  9. In This Issue

    NASA Astrophysics Data System (ADS)

    Warner, Brian D.

    2018-04-01

    This list gives those asteroids in this issue for which physical observations (excluding astrometric only) were made. This includes lightcurves, color index, and H-G determinations, etc. In some cases, no specific results are reported due to a lack of or poor quality data. The page number is for the first page of the paper mentioning the asteroid. EP is the "go to page" value in the electronic version.

  10. The Construction of Physics as a Quintessentially Masculine Subject: Young People's Perceptions of Gender Issues in Access to Physics.

    PubMed

    Francis, Becky; Archer, Louise; Moote, Julie; DeWitt, Jen; MacLeod, Emily; Yeomans, Lucy

    2017-01-01

    The present article investigates explanations for gendered trends in Physics and Engineering access, reporting findings from a large-scale study funded by the UK Economic and Social Research Council and drawing primarily on data from interviews with 132 15-16 year-old adolescents and their parents. Survey results in our study and elsewhere show strong gender disparities in anticipated pursuit of Physics after completion of compulsory education. In order to explore the constructions of gender and Physics underlying these trends, we focus on qualitative interview data, applying Foucaultian analysis of discourse to investigate gendered narratives underpinning adolescents' and their parents' articulations. This analysis reveals three key discourses at work on the topic of women's access to Physics: (a) equality of opportunity, (b) continued gender discrimination in and around Physics, and (c) Physics as quintessentially masculine. We additionally identify five distinct narratives supporting the discourse of physics as masculine. These various discourses and narratives are interrogated, and their implications explored. We conclude that it is only by disrupting prevalent constructions of the Physical sciences as a masculine and "hard" domain will we increase the presence of women in the sector. Working with young people to analyse and deconstruct the discursive assumptions made in relation to gender and Physics, as well as further work to increase accessibility and broaden representation in Physics, may be fruitful ways to challenge these longstanding associations between Physics and masculinity.

  11. The Campus Executive's Role in Security and Liability Issues.

    ERIC Educational Resources Information Center

    Bromley, Max; Territo, Leonard

    1986-01-01

    Executives at institutions of higher education have become increasingly concerned about serious crimes being committed on their campuses. The liability issue, criminal activity information, physical security and design issues, student patrol escorts, crime prevention training, and task force development are discussed. (MLW)

  12. Girls into Physics--Looking Back and Looking Forward

    ERIC Educational Resources Information Center

    Thomson, Clare

    2011-01-01

    Girls are under-represented in physics post-16. They continue to make up only 22% of those taking A-level Physics, despite the many changes in the educational system over the last 20 years. This article looks at the work the Institute of Physics has undertaken to address the issue. After outlining the key issues that were identified in work…

  13. Reproductive issues in anorexia nervosa

    PubMed Central

    Hoffman, Elizabeth R; Zerwas, Stephanie C; Bulik, Cynthia M

    2011-01-01

    Despite a high prevalence of menstrual irregularities, women with anorexia nervosa are becoming pregnant. The physical and psychological demands of pregnancy and motherhood can represent an immense challenge for women already struggling with the medical and psychological stress of an eating disorder. This article summarizes key issues related to reproduction in women with anorexia nervosa, highlighting the importance of preconception counseling, adequate gestational weight gain, and sufficient pre- and post-natal nutrition. Postpartum issues including eating disorder symptom relapse, weight loss, breastfeeding, and risk of perinatal depression and anxiety are also discussed. PMID:22003362

  14. Observations of Spacecraft Targets, Unusual Asteroids, and Targets of Opportunity

    NASA Technical Reports Server (NTRS)

    Tholen, David J.

    1998-01-01

    Obtain physical and astrometric observations of: (1) spacecraft targets to support mission operations; (2) known asteroids with unusual orbits to help determine their origin; and (3) newly discovered minor planets (including both asteroids and comets) that represent a particular opportunity to add significant new knowledge of the Solar System.

  15. Current Technology Trends and Issues among Health and Physical Education Professionals

    ERIC Educational Resources Information Center

    Krause, Jennifer M.; Franks, Hillary; Lynch, Brandy

    2017-01-01

    Health and physical education professionals who implement technology appropriately can contribute to helping students become physically educated individuals (NASPE, 2009). It is imperative that professionals be knowledgeable and resourceful in how to integrate technology effectively, but it is unclear what current challenges professionals face in…

  16. Foreword to the Special Issue on Ejecta

    DOE PAGES

    Buttler, William Tillman; Williams, Robin J. R.; Najjar, Fady M.

    2017-05-22

    We report that ejecta physics is a young field, having developed over the last 60 years or so. Essentially, ejecta forms as a spray of dense particles generated from the free surface of metals subjected to strong shocks, but the detailed mechanisms controlling the properties of this particulate ejecta are only now being fully elucidated. The field is dynamic and rapidly growing, with military and industrial applications, and applications to areas such as fusion research. This Special Issue on Ejecta reports the current state of the art in ejecta physics, describing experimental, theoretical and computational work by research groups aroundmore » the world. While much remains to be done, the dramatic recent progress in the field, some of it first reported here, means that this volume provides a particularly timely review. In this foreword, we provide a brief historical overview of the development of ejecta physics, to define the context for the work in the rest of this Special Issue.« less

  17. Women in physical medicine and rehabilitation. Leadership issues.

    PubMed

    Wong, E Y; Cardenas, D D

    2001-02-01

    Academic medical centers share the triple missions of education, research, and clinical care, particularly in vulnerable populations. They are well positioned to have a significant impact on reducing health disparities between patients from diverse backgrounds, both now and in future generations. A key component to realizing this goal lies in increasing the number of women in academic medicine. Women bring a fresh perspective to the investigative process, often targeting gender is a better way of providing preventive services, and patient satisfaction studies have shown that many patients prefer women physicians.

  18. Current Issues in Flexibility Fitness.

    ERIC Educational Resources Information Center

    Knudson, Duane V.; Magnusson, Peter; McHugh, Malachy

    2000-01-01

    Physical activity is extremely important in maintaining good health. Activity is not possible without a certain amount of flexibility. This report discusses issues related to flexibility fitness. Flexibility is a property of the musculoskeletal system that determines the range of motion achievable without injury to the joints. Static flexibility…

  19. Renaissance of the ~1 TeV Fixed-Target Program

    NASA Astrophysics Data System (ADS)

    Adams, T.; Appel, J. A.; Arms, K. E.; Balantekin, A. B.; Conrad, J. M.; Cooper, P. S.; Djurcic, Z.; Dunwoodie, W.; Engelfried, J.; Fisher, P. H.; Gottschalk, E.; de Gouvea, A.; Heller, K.; Ignarra, C. M.; Karagiorgi, G.; Kwan, S.; Loinaz, W. A.; Meadows, B.; Moore, R.; Morfín, J. G.; Naples, D.; Nienaber, P.; Pate, S. F.; Papavassiliou, V.; Petrov, A. A.; Purohit, M. V.; Ray, H.; Russ, J.; Schwartz, A. J.; Seligman, W. G.; Shaevitz, M. H.; Schellman, H.; Spitz, J.; Syphers, M. J.; Tait, T. M. P.; Vannucci, F.

    This document describes the physics potential of a new fixed-target program based on a ~1 TeV proton source. Two proton sources are potentially available in the future: the existing Tevatron at Fermilab, which can provide 800 GeV protons for fixed-target physics, and a possible upgrade to the SPS at CERN, called SPS+, which would produce 1 TeV protons on target. In this paper we use an example Tevatron fixed-target program to illustrate the high discovery potential possible in the charm and neutrino sectors. We highlight examples which are either unique to the program or difficult to accomplish at other venues.

  20. Renaissance of the ~ 1-TeV Fixed-Target Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Adams, T.; /Florida State U.; Appel, J.A.

    2011-12-02

    This document describes the physics potential of a new fixed-target program based on a {approx}1 TeV proton source. Two proton sources are potentially available in the future: the existing Tevatron at Fermilab, which can provide 800 GeV protons for fixed-target physics, and a possible upgrade to the SPS at CERN, called SPS+, which would produce 1 TeV protons on target. In this paper we use an example Tevatron fixed-target program to illustrate the high discovery potential possible in the charm and neutrino sectors. We highlight examples which are either unique to the program or difficult to accomplish at other venues.

  1. Promoting Physical Activity in Secondary Schools: Growing Expectations, "Same Old" Issues?

    ERIC Educational Resources Information Center

    Cale, Lorraine; Harris, Jo; Duncombe, Rebecca

    2016-01-01

    There are growing expectations on schools to promote health and physical activity and helping schools to effectively do so is considered a priority. This paper reports on selected findings from a research project that was concerned with supporting secondary schools in the effective promotion of physical activity and establishing their needs in…

  2. Challenges Surrounding the Injection and Arrival of Targets at LIFE Fusion Chamber Center

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miles, R; Spaeth, M; Manes, K

    2010-12-01

    IFE target designers must consider several engineering requirements in addition to the physics requirements for successful target implosion. These considerations include low target cost, high manufacturing throughput, the ability of the target to survive the injection into the fusion chamber and arrive in a condition and physical position consistent with proper laser-target interaction and ease of post-implosion debris removal. This article briefly describes these considerations for the Laser Inertial Fusion-based Energy (LIFE) targets currently being designed.

  3. Systematic review and meta-analysis of interventions targeting sleep and their impact on child body mass index, diet, and physical activity.

    PubMed

    Yoong, Sze Lin; Chai, Li Kheng; Williams, Christopher M; Wiggers, John; Finch, Meghan; Wolfenden, Luke

    2016-05-01

    This review aimed to examine the impact of interventions involving an explicit sleep component on child body mass index (BMI), diet, and physical activity. A systematic search was undertaken in six databases to identify randomized controlled trials examining the impact of interventions with a sleep component on child BMI, dietary intake, and/or physical activity. A random effects meta-analysis was conducted assessing the impact of included interventions on child BMI. Of the eight included trials, three enforced a sleep protocol and five targeted sleep as part of multicomponent behavioral interventions either exclusively or together with nutrition and physical activity. Meta-analysis of three studies found that multicomponent behavioral interventions involving a sleep component were not significantly effective in changing child BMI (n = 360,-0.04 kg/m(2) [-0.18, 0.11], I(2)  = 0%); however, only one study included in the meta-analysis successfully changed sleep duration in children. There were some reported improvements to adolescent diet, and only one trial examined the impact on child physical activity, where a significant effect was observed. Findings from the included studies suggest that where improvements in child sleep duration were achieved, a positive impact on child BMI, nutrition, and physical activity was also observed. © 2016 The Obesity Society.

  4. Are Most People Too Dumb for Physics?

    ERIC Educational Resources Information Center

    Lasry, Nathaniel; Finkelstein, Noah; Mazur, Eric

    2009-01-01

    In last month's issue of "TPT," Michael Sobel turns our attention to the increasing number and broader population of students taking physics courses and urges us to reconsider how to better cater to their needs. We applaud the author for focusing our attention on this important issue. However, we find his proposal for teaching physics to…

  5. Addressing Teachers' Feelings of Lack of Control over Policy Issues

    ERIC Educational Resources Information Center

    Judson, Eugene

    2014-01-01

    This study reports on how an American Education System course, traditionally taught with broad objectives, was contextualized for science teachers. Using pre-assessment data, specific policy issues were targeted with the objective of increasing teachers' feelings of influence over issues. The approach used was adapted from exposure therapy, a…

  6. Characterization studies of prototype ISOL targets for the RIA

    NASA Astrophysics Data System (ADS)

    Greene, John P.; Burtseva, Tatiana; Neubauer, Janelle; Nolen, Jerry A.; Villari, Antonio C. C.; Gomes, Itacil C.

    2005-12-01

    Targets employing refractory compounds are being developed for the rare isotope accelerator (RIA) facility to produce ion species far from stability. With the 100 kW beams proposed for the production targets, dissipation of heat becomes a challenging issue. In our two-step target design, neutrons are generated in a refractory primary target, inducing fission in the surrounding uranium carbide. The interplay of density, grain size, thermal conductivity and diffusion properties of the UC2 needs to be well understood before fabrication. Thin samples of uranium carbide were prepared for thermal conductivity measurements using an electron beam to heat the sample and an optical pyrometer to observe the thermal radiation. Release efficiencies and independent thermal analysis on these samples are being undertaken at Oak Ridge National Laboratory (ORNL). An alternate target concept for RIA, the tilted slab approach promises to be simple with fast ion release and capable of withstanding high beam intensities while providing considerable yields via spallation. A proposed small business innovative research (SBIR) project will design a prototype tilted target, exploring the materials needed for fabrication and testing at an irradiation facility to address issues of heat transfer and stresses within the target.

  7. 36 CFR 72.12 - Assessment of needs, problems and issues.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... used for citizen participation. (b) Physical Issues. Summary information should be provided on existing... such activities. (c) Rehabilitation Issues. Summary information should be provided on the need for... sites and properties for rehabilitation; (3) Importance of rehabilitation in specific geographic areas...

  8. Interventions to improve physical activity during pregnancy: a systematic review on issues of internal and external validity using the RE-AIM framework.

    PubMed

    Craike, M; Hill, B; Gaskin, C J; Skouteris, H

    2017-03-01

    Physical activity (PA) during pregnancy has significant health benefits for the mother and her child; however, many women reduce their activity levels during pregnancy and most are not sufficiently active. Given the important health benefits of PA during pregnancy, evidence that supports research translation is vital. To determine the extent to which physical activity interventions for pregnant women report on internal and external validity factors using the RE-AIM framework (reach, efficacy/effectiveness, adoption, implementation, and maintenance). Ten databases were searched up to 1 June 2015. Eligible published papers and unpublished/grey literature were identified using relevant search terms. Studies had to report on physical activity interventions during pregnancy, including measures of physical activity during pregnancy at baseline and at least one point post-intervention. Randomised controlled trials and quasi-experimental studies that had a comparator group were included. Reporting of RE-AIM dimensions were summarised and synthesised across studies. The reach (72.1%) and efficacy/effectiveness (71.8%) dimensions were commonly reported; however, the implementation (28.9%) and adoption (23.2%) dimensions were less commonly reported and no studies reported on maintenance. This review highlights the under-reporting of issues of contextual factors in studies of physical activity during pregnancy. The translation of physical activity interventions during pregnancy could be improved through reporting of representativeness of participants, clearer reporting of outcomes, more detail on the setting and staff who deliver interventions, costing of interventions and the inclusion of process evaluations and qualitative data. The systematic review highlights the under-reporting of contextual factors in studies of physical activity during pregnancy. © 2016 Royal College of Obstetricians and Gynaecologists.

  9. A systematic review of eHealth behavioral interventions targeting smoking, nutrition, alcohol, physical activity and/or obesity for young adults.

    PubMed

    Oosterveen, Emilie; Tzelepis, Flora; Ashton, Lee; Hutchesson, Melinda J

    2017-06-01

    A systematic review of randomized control trials (RCT) was undertaken to evaluate the effectiveness of eHealth behavioral interventions aiming to improve smoking rates, nutrition behaviors, alcohol intake, physical activity levels and/or obesity (SNAPO) in young adults. Seven electronic databases were searched for RCTs published in English from 2000 to April 2015 and evaluating eHealth interventions aiming to change one or multiple SNAPO outcomes, and including young adult (18-35years) participants. Of 2,159 articles identified, 45 studies met the inclusion criteria. Most interventions targeted alcohol (n=26), followed by smoking (n=7), physical activity (n=4), obesity (n=4) and nutrition (n=1). Three interventions targeted multiple behaviors. The eHealth interventions were most often delivered via websites (79.5%). Most studies (n=32) compared eHealth interventions to a control group (e.g. waiting list control, minimal intervention), with the majority (n=23) showing a positive effect on a SNAPO outcome at follow-up. Meta-analysis demonstrated a significantly lower mean number of drinks consumed/week in brief web or computer-based interventions compared to controls (Mean Difference -2.43 [-3.54, -1.32], P<0.0001, n=10). Sixteen studies compared eHealth delivery modes, with inconsistent results across target behaviors and technology types. Nine studies compared eHealth to other modes of delivery (e.g. in person) with all finding no difference in SNAPO outcomes between groups at follow-up. This review provides some evidence for the efficacy of eHealth SNAPO interventions for young adults, particularly in the short-term and for alcohol interventions. But there is insufficient evidence for their efficacy in the longer-term, as well as which mode of delivery is most effective. Crown Copyright © 2017. Published by Elsevier Inc. All rights reserved.

  10. Effectiveness of interventions targeting physical activity, nutrition and healthy weight for university and college students: a systematic review and meta-analysis.

    PubMed

    Plotnikoff, Ronald C; Costigan, Sarah A; Williams, Rebecca L; Hutchesson, Melinda J; Kennedy, Sarah G; Robards, Sara L; Allen, Jennifer; Collins, Clare E; Callister, Robin; Germov, John

    2015-04-01

    To examine the effectiveness of interventions aimed at improving physical activity, diet, and/or weight-related behaviors amongst university/college students. Five online databases were searched (January 1970 to April 2014). Experimental study designs were eligible for inclusion. Data extraction was performed by one reviewer using a standardized form developed by the researchers and checked by a second reviewer. Data were described in a narrative synthesis and meta-analyses were conducted when appropriate. Study quality was also established. Forty-one studies were included; of these, 34 reported significant improvements in one of the key outcomes. Of the studies examining physical activity 18/29 yielded significant results, with meta-analysis demonstrating significant increases in moderate physical activity in intervention groups compared to control. Of the studies examining nutrition, 12/24 reported significantly improved outcomes; only 4/12 assessing weight loss outcomes found significant weight reduction. This appears to be the first systematic review of physical activity, diet and weight loss interventions targeting university and college students. Tertiary institutions are appropriate settings for implementing and evaluating lifestyle interventions, however more research is needed to improve such strategies.

  11. Liquid Hydrogen Target Experience at SLAC

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weisend, J.G.; Boyce, R.; Candia, A.

    2005-08-29

    Liquid hydrogen targets have played a vital role in the physics program at SLAC for the past 40 years. These targets have ranged from small ''beer can'' targets to the 1.5 m long E158 target that was capable of absorbing up to 800 W without any significant density changes. Successful use of these targets has required the development of thin wall designs, liquid hydrogen pumps, remote positioning and alignment systems, safety systems, control and data acquisition systems, cryogenic cooling circuits and heat exchangers. Detailed operating procedures have been created to ensure safety and operational reliability. This paper surveys the evolutionmore » of liquid hydrogen targets at SLAC and discusses advances in several of the enabling technologies that made these targets possible.« less

  12. Harassment, stalking, threats and attacks targeting New Zealand politicians: A mental health issue.

    PubMed

    Every-Palmer, Susanna; Barry-Walsh, Justin; Pathé, Michele

    2015-07-01

    Due to the nature of their work, politicians are at greater risk of stalking, harassment and attack than the general population. The small, but significantly elevated risk of violence to politicians is predominantly due not to organised terrorism or politically motivated extremists but to fixated individuals with untreated serious mental disorders, usually psychosis. Our objective was to ascertain the frequency, nature and effects of unwanted harassment of politicians in New Zealand and the possible role of mental illness in this harassment. New Zealand Members of Parliament were surveyed, with an 84% response rate (n = 102). Quantitative and qualitative data were collected on Parliamentarians' experiences of harassment and stalking. Eighty-seven percent of politicians reported unwanted harassment ranging from disturbing communications to physical violence, with most experiencing harassment in multiple modalities and on multiple occasions. Cyberstalking and other forms of online harassment were common, and politicians felt they (and their families) had become more exposed as a result of the Internet. Half of MPs had been personally approached by their harassers, 48% had been directly threatened and 15% had been attacked. Some of these incidents were serious, involving weapons such as guns, Molotov cocktails and blunt instruments. One in three politicians had been targeted at their homes. Respondents believed the majority of those responsible for the harassment exhibited signs of mental illness. The harassment of politicians in New Zealand is common and concerning. Many of those responsible were thought to be mentally ill by their victims. This harassment has significant psychosocial costs for both the victim and the perpetrator and represents an opportunity for mental health intervention. © The Royal Australian and New Zealand College of Psychiatrists 2015.

  13. Harassment, stalking, threats and attacks targeting New Zealand politicians: A mental health issue

    PubMed Central

    Every-Palmer, Susanna; Barry-Walsh, Justin; Pathé, Michele

    2015-01-01

    Objective: Due to the nature of their work, politicians are at greater risk of stalking, harassment and attack than the general population. The small, but significantly elevated risk of violence to politicians is predominantly due not to organised terrorism or politically motivated extremists but to fixated individuals with untreated serious mental disorders, usually psychosis. Our objective was to ascertain the frequency, nature and effects of unwanted harassment of politicians in New Zealand and the possible role of mental illness in this harassment. Methods: New Zealand Members of Parliament were surveyed, with an 84% response rate (n = 102). Quantitative and qualitative data were collected on Parliamentarians’ experiences of harassment and stalking. Results: Eighty-seven percent of politicians reported unwanted harassment ranging from disturbing communications to physical violence, with most experiencing harassment in multiple modalities and on multiple occasions. Cyberstalking and other forms of online harassment were common, and politicians felt they (and their families) had become more exposed as a result of the Internet. Half of MPs had been personally approached by their harassers, 48% had been directly threatened and 15% had been attacked. Some of these incidents were serious, involving weapons such as guns, Molotov cocktails and blunt instruments. One in three politicians had been targeted at their homes. Respondents believed the majority of those responsible for the harassment exhibited signs of mental illness. Conclusion: The harassment of politicians in New Zealand is common and concerning. Many of those responsible were thought to be mentally ill by their victims. This harassment has significant psychosocial costs for both the victim and the perpetrator and represents an opportunity for mental health intervention. PMID:25954019

  14. Cyber-physical security of Wide-Area Monitoring, Protection and Control in a smart grid environment

    PubMed Central

    Ashok, Aditya; Hahn, Adam; Govindarasu, Manimaran

    2013-01-01

    Smart grid initiatives will produce a grid that is increasingly dependent on its cyber infrastructure in order to support the numerous power applications necessary to provide improved grid monitoring and control capabilities. However, recent findings documented in government reports and other literature, indicate the growing threat of cyber-based attacks in numbers and sophistication targeting the nation’s electric grid and other critical infrastructures. Specifically, this paper discusses cyber-physical security of Wide-Area Monitoring, Protection and Control (WAMPAC) from a coordinated cyber attack perspective and introduces a game-theoretic approach to address the issue. Finally, the paper briefly describes how cyber-physical testbeds can be used to evaluate the security research and perform realistic attack-defense studies for smart grid type environments. PMID:25685516

  15. Cyber-physical security of Wide-Area Monitoring, Protection and Control in a smart grid environment.

    PubMed

    Ashok, Aditya; Hahn, Adam; Govindarasu, Manimaran

    2014-07-01

    Smart grid initiatives will produce a grid that is increasingly dependent on its cyber infrastructure in order to support the numerous power applications necessary to provide improved grid monitoring and control capabilities. However, recent findings documented in government reports and other literature, indicate the growing threat of cyber-based attacks in numbers and sophistication targeting the nation's electric grid and other critical infrastructures. Specifically, this paper discusses cyber-physical security of Wide-Area Monitoring, Protection and Control (WAMPAC) from a coordinated cyber attack perspective and introduces a game-theoretic approach to address the issue. Finally, the paper briefly describes how cyber-physical testbeds can be used to evaluate the security research and perform realistic attack-defense studies for smart grid type environments.

  16. TARGET: Rapid Capture of Process Knowledge

    NASA Technical Reports Server (NTRS)

    Ortiz, C. J.; Ly, H. V.; Saito, T.; Loftin, R. B.

    1993-01-01

    TARGET (Task Analysis/Rule Generation Tool) represents a new breed of tool that blends graphical process flow modeling capabilities with the function of a top-down reporting facility. Since NASA personnel frequently perform tasks that are primarily procedural in nature, TARGET models mission or task procedures and generates hierarchical reports as part of the process capture and analysis effort. Historically, capturing knowledge has proven to be one of the greatest barriers to the development of intelligent systems. Current practice generally requires lengthy interactions between the expert whose knowledge is to be captured and the knowledge engineer whose responsibility is to acquire and represent the expert's knowledge in a useful form. Although much research has been devoted to the development of methodologies and computer software to aid in the capture and representation of some types of knowledge, procedural knowledge has received relatively little attention. In essence, TARGET is one of the first tools of its kind, commercial or institutional, that is designed to support this type of knowledge capture undertaking. This paper will describe the design and development of TARGET for the acquisition and representation of procedural knowledge. The strategies employed by TARGET to support use by knowledge engineers, subject matter experts, programmers and managers will be discussed. This discussion includes the method by which the tool employs its graphical user interface to generate a task hierarchy report. Next, the approach to generate production rules for incorporation in and development of a CLIPS based expert system will be elaborated. TARGET also permits experts to visually describe procedural tasks as a common medium for knowledge refinement by the expert community and knowledge engineer making knowledge consensus possible. The paper briefly touches on the verification and validation issues facing the CLIPS rule generation aspects of TARGET. A description of

  17. MO-FG-BRB-02: Debater [medical physics education

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hazle, J.

    Building on the energy and excitement of Washington DC in a presidential election year, AAPM will host its own Presidential Debate to better understand the views of the AAPM membership! Past presidents of the AAPM, Drs. Bayouth, Hazle, Herman, and Seibert, will debate hot topics in medical physics including issues facing education, professional practice, and the advancement of science. The moderators, Drs. Brock and Stern, will also draw in topics from Point-Counterpoint articles from the Medical Physics Journals. Wrapping up the debate, the audience will have the opportunity to question the candidates in a town hall format. At the conclusionmore » of this lively debate, the winner will be decided by the audience, so bring your Audience Response Units! Be part of Medical Physics - Decision 2016! Learning Objectives: Understand AAPM members’ views and opinions on issues facing medical physics education Learn AAPM members’ views and opinions on issues facing professional practice Identify AAPM members’ view and opinions on issues facing the advancement of science in medical physics J. Bayouth, Funding support from NCI;Scientific Advisory Board member - ViewRay.« less

  18. MO-FG-BRB-04: Debater [Medical physics education

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Seibert, J.

    Building on the energy and excitement of Washington DC in a presidential election year, AAPM will host its own Presidential Debate to better understand the views of the AAPM membership! Past presidents of the AAPM, Drs. Bayouth, Hazle, Herman, and Seibert, will debate hot topics in medical physics including issues facing education, professional practice, and the advancement of science. The moderators, Drs. Brock and Stern, will also draw in topics from Point-Counterpoint articles from the Medical Physics Journals. Wrapping up the debate, the audience will have the opportunity to question the candidates in a town hall format. At the conclusionmore » of this lively debate, the winner will be decided by the audience, so bring your Audience Response Units! Be part of Medical Physics - Decision 2016! Learning Objectives: Understand AAPM members’ views and opinions on issues facing medical physics education Learn AAPM members’ views and opinions on issues facing professional practice Identify AAPM members’ view and opinions on issues facing the advancement of science in medical physics J. Bayouth, Funding support from NCI;Scientific Advisory Board member - ViewRay.« less

  19. MO-FG-BRB-01: Debater [medical physics education

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bayouth, J.

    Building on the energy and excitement of Washington DC in a presidential election year, AAPM will host its own Presidential Debate to better understand the views of the AAPM membership! Past presidents of the AAPM, Drs. Bayouth, Hazle, Herman, and Seibert, will debate hot topics in medical physics including issues facing education, professional practice, and the advancement of science. The moderators, Drs. Brock and Stern, will also draw in topics from Point-Counterpoint articles from the Medical Physics Journals. Wrapping up the debate, the audience will have the opportunity to question the candidates in a town hall format. At the conclusionmore » of this lively debate, the winner will be decided by the audience, so bring your Audience Response Units! Be part of Medical Physics - Decision 2016! Learning Objectives: Understand AAPM members’ views and opinions on issues facing medical physics education Learn AAPM members’ views and opinions on issues facing professional practice Identify AAPM members’ view and opinions on issues facing the advancement of science in medical physics J. Bayouth, Funding support from NCI;Scientific Advisory Board member - ViewRay.« less

  20. MO-FG-BRB-03: Debater [medical physics education

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Herman, M.

    Building on the energy and excitement of Washington DC in a presidential election year, AAPM will host its own Presidential Debate to better understand the views of the AAPM membership! Past presidents of the AAPM, Drs. Bayouth, Hazle, Herman, and Seibert, will debate hot topics in medical physics including issues facing education, professional practice, and the advancement of science. The moderators, Drs. Brock and Stern, will also draw in topics from Point-Counterpoint articles from the Medical Physics Journals. Wrapping up the debate, the audience will have the opportunity to question the candidates in a town hall format. At the conclusionmore » of this lively debate, the winner will be decided by the audience, so bring your Audience Response Units! Be part of Medical Physics - Decision 2016! Learning Objectives: Understand AAPM members’ views and opinions on issues facing medical physics education Learn AAPM members’ views and opinions on issues facing professional practice Identify AAPM members’ view and opinions on issues facing the advancement of science in medical physics J. Bayouth, Funding support from NCI;Scientific Advisory Board member - ViewRay.« less

  1. Women in physics in France

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pierron-Bohnes, Véronique

    We present six associations and entities working in France on issues of women in physics: the Women and Physics Commission, French Physical Society; Women in Nuclear (WiN) France; Women and Science Association; Mission for the Place of Women at CNRS; Parity, Diversity, and Women Network, CEA; and the Network of University Equality-Diversity Representatives.

  2. Special Issue: "Molecules against Alzheimer".

    PubMed

    Decker, Michael; Muñoz-Torrero, Diego

    2016-12-16

    This Special Issue, entitled "Molecules against Alzheimer", gathers a number of original articles, short communications, and review articles on recent research efforts toward the development of novel drug candidates, diagnostic agents and therapeutic approaches for Alzheimer's disease (AD), the most prevalent neurodegenerative disorder and a leading cause of death worldwide. This Special Issue contains many interesting examples describing the design, synthesis, and pharmacological profiling of novel compounds that hit one or several key biological targets, such as cholinesterases, β-amyloid formation or aggregation, monoamine oxidase B, oxidative stress, biometal dyshomeostasis, mitochondrial dysfunction, serotonin and/or melatonin systems, the Wnt/β-catenin pathway, sigma receptors, nicotinamide phosphoribosyltransferase, or nuclear erythroid 2-related factor. The development of novel AD diagnostic agents based on tau protein imaging and the use of lithium or intranasal insulin for the prevention or the symptomatic treatment of AD is also covered in some articles of the Special Issue.

  3. Personalized targeted therapy for esophageal squamous cell carcinoma

    PubMed Central

    Kang, Xiaozheng; Chen, Keneng; Li, Yicheng; Li, Jianying; D'Amico, Thomas A; Chen, Xiaoxin

    2015-01-01

    Esophageal squamous cell carcinoma continues to heavily burden clinicians worldwide. Researchers have discovered the genomic landscape of esophageal squamous cell carcinoma, which holds promise for an era of personalized oncology care. One of the most pressing problems facing this issue is to improve the understanding of the newly available genomic data, and identify the driver-gene mutations, pathways, and networks. The emergence of a legion of novel targeted agents has generated much hope and hype regarding more potent treatment regimens, but the accuracy of drug selection is still arguable. Other problems, such as cancer heterogeneity, drug resistance, exceptional responders, and side effects, have to be surmounted. Evolving topics in personalized oncology, such as interpretation of genomics data, issues in targeted therapy, research approaches for targeted therapy, and future perspectives, will be discussed in this editorial. PMID:26167067

  4. Philosophy of Physics

    NASA Astrophysics Data System (ADS)

    Crease, Robert P.

    2017-10-01

    There are some physics controversies that no amount of physics research can answer. Why is doing string theory scientific despite its lack of empirical predictions? How should we interpret quantum mechanics? What is the nature of time and space? What constitutes fundamental physics? One can answer these questions dogmatically by appealing to textbooks or by making rough and ready pronouncements, but the issues behind them can often be significantly clarified by the sort of systematic, critical reflection that philosophy practices. Philosophy comes in several traditions. Three of these-known as 'analytic,' 'pragmatic' and 'continental'-have paid particular attention to physics. This ebook illustrates philosophy of physics in action, and how it can help physics, by using four examples from physics to exhibit the aims and value of these philosophical approaches.

  5. Conducting Ethical Evaluations with Disadvantaged and Minority Target Groups.

    ERIC Educational Resources Information Center

    English, Brian

    1997-01-01

    This paper examines issues involved in conducting evaluations when participation by the target groups, typically minorities and disadvantaged groups, may put them in jeopardy. Argues that participation by target groups as cooperative partners throughout the evaluation is a way of addressing this dilemma. (SLD)

  6. Striatal activity is modulated by target probability.

    PubMed

    Hon, Nicholas

    2017-06-14

    Target probability has well-known neural effects. In the brain, target probability is known to affect frontal activity, with lower probability targets producing more prefrontal activation than those that occur with higher probability. Although the effect of target probability on cortical activity is well specified, its effect on subcortical structures such as the striatum is less well understood. Here, I examined this issue and found that the striatum was highly responsive to target probability. This is consistent with its hypothesized role in the gating of salient information into higher-order task representations. The current data are interpreted in light of that fact that different components of the striatum are sensitive to different types of task-relevant information.

  7. Magnetized Target Fusion: Prospects for Low-Cost Fusion Energy

    NASA Technical Reports Server (NTRS)

    Siemon, Richard E.; Turchi, Peter J.; Barnes, Daniel C.; Degnan, James; Parks, Paul; Ryutov, Dmitri D.; Thio, Y. C. Francis; Schafer, Charles (Technical Monitor)

    2001-01-01

    Magnetized Target Fusion (MTF) has attracted renewed interest in recent years because it has the potential to resolve one of the major problems with conventional fusion energy research - the high cost of facilities to do experiments and in general develop practical fusion energy. The requirement for costly facilities can be traced to fundamental constraints. The Lawson condition implies large system size in the case of conventional magnetic confinement, or large heating power in the case of conventional inertial confinement. The MTF approach is to use much higher fuel density than with conventional magnetic confinement (corresponding to megabar pressures), which results in a much-reduced system size to achieve Lawson conditions. Intrinsically the system must be pulsed because the pressures exceed the strength of any known material. To facilitate heating the fuel (or "target") to thermonuclear conditions with a high-power high-intensity source of energy, magnetic fields are used to insulate the high-pressure fuel from material surroundings (thus "magnetized target"). Because of magnetic insulation, the required heating power intensity is reduced by many orders of magnitude compared to conventional inertial fusion, even with relatively poor energy confinement in the magnetic field, such as that characterized by Bohm diffusion. In this paper we show semi-quantitatively why MTF-should allow fusion energy production without costly facilities within the same generally accepted physical constraints used for conventional magnetic and inertial fusion. We also briefly discuss potential applications of this technology ranging from nuclear rockets for space propulsion to a practical commercial energy system. Finally, we report on the exploratory research underway, and the interesting physics issues that arise in the MTF regime of parameters. Experiments at Los Alamos are focused on formation of a suitable plasma target for compression, utilizing the knowledge base for compact

  8. Applied Physics Lab Kennedy Space Center: Recent Contributions

    NASA Technical Reports Server (NTRS)

    Starr, Stan; Youngquist, Robert

    2006-01-01

    The mission of the Applied Physics Lab is: (1) Develop and deliver novel sensors and devices to support KSC mission operations. (2) Analyze operational issues and recommend or deliver practical solutions. (3) Apply physics to the resolution of long term space flight issues that affect space port operation on Earth or on other planets.

  9. Molecular targeting agents in cancer therapy: science and society.

    PubMed

    Shaikh, Asim Jamal

    2012-01-01

    The inception of targeted agents has revolutionized the cancer therapy paradigm, both for physicians and patients. A large number of molecular targeted agents for cancer therapy are currently available for clinical use today. Many more are in making, but there are issues that remain to be resolved for the scientific as well as social community before the recommendation of their widespread use in may clinical scenarios can be done, one such issue being cost and cost effectiveness, others being resistance and lack of sustained efficacy. With the current knowledge about available targeted agents, the growing knowledge of intricate molecular pathways and unfolding of wider spectrum of molecular targets that can really matter in the disease control, calls for only the just use of the agents available now, drug companies need to make a serious attempt to reduce the cost of the agents. Research should focus on agents that show sustained responses in preclinical data. More needs to be done in laboratories and by the pharmaceutical industries, before we can truly claim to have entered a new era of targeted therapy in cancer care.

  10. JPRS Report, Proliferation Issues

    DTIC Science & Technology

    1992-10-30

    systemChina, the potential is there for enormous profits to be is marketed as a high-speed target drone , that can be usedmade. for training anti-aircraft and...maintenance support equipment, fully transportable by modernisation of older weapons systems. During the arms road, sea and air. The drone can be controlled...said the whole issue was and speculation. The Drone goes on display at the DEXSA shrouded in secrecy. 󈨠 Exposition, the report concludes. He said the

  11. Cooled particle accelerator target

    DOEpatents

    Degtiarenko, Pavel V.

    2005-06-14

    A novel particle beam target comprising: a rotating target disc mounted on a retainer and thermally coupled to a first array of spaced-apart parallel plate fins that extend radially inwardly from the retainer and mesh without physical contact with a second array of spaced-apart parallel plate fins that extend radially outwardly from and are thermally coupled to a cooling mechanism capable of removing heat from said second array of spaced-apart fins and located within the first array of spaced-apart parallel fins. Radiant thermal exchange between the two arrays of parallel plate fins provides removal of heat from the rotating disc. A method of cooling the rotating target is also described.

  12. Communicating Prevention Messages to Policy Makers: The Role of Stories in Promoting Physical Activity

    PubMed Central

    Stamatakis, Katherine A.; McBride, Timothy D.; Brownson, Ross C.

    2014-01-01

    Background While effective interventions to promote physical activity have been identified, efforts to translate these interventions into policy have lagged behind. In order to improve the translation of evidence into policy, researchers and public health practitioners need to consider new ways for communicating health promoting messages to state and local policymakers. Methods In this article, we describe issues related to the translation of evidence supporting physical activity promotion, and offer some communication approaches and tools that are likely to be beneficial in translating research to policy. Results We discuss the use of narrative (i.e., stories) and describe its potential role in improving communication of research in policy-making settings. In addition, we provide an outline for the development and design of policy briefs on physical activity, and for how to target these briefs effectively to policy-oriented audiences. Conclusions Improvements in researchers' and practitioners' abilities to translate the evidence they generate into high-quality materials for policy makers can greatly enhance efforts to enact policies that promote physical activity. PMID:20440020

  13. Negotiating targets with patients: choice of target in relation to occupational state.

    PubMed

    Robinson, Sandra M; Walker, David J

    2012-02-01

    Following the recent National Institute for Health and Clinical Excellence guidance on the management of RA, we were interested to see if we could negotiate targets for treatment with patients in routine clinics, how they would express this and whether staying at work would be a target. One hundred RA patients were recruited. They were consecutive within clinics, but not all clinics were used. They were asked their understanding of the DAS score and a target for treatment negotiated. Any impact of the RA on their paid employment was then explored. Four participants were unable to specify a target for their RA. Negotiated targets were expressed as restricted activities and either as maintaining an activity (70) if the disease was stable, or regaining an activity (26) if the treatment was being increased. Targets were walking a distance for 50% of patients; leisure activities for 18%; domestic activities for 17%; work for 14% and personal care for 2%. For the 21 participants currently working, maintaining work was the target for 12, with 1 wishing to regain lost hours. No patient currently not working expressed returning to work as a target. There were some differences in targets between men and women. Patients are able to negotiate a target for their treatment, expressed as maintaining or regaining a physical activity. Work ceases to be a target once it is lost. Therefore, preventing loss of occupation is likely to be more effective than trying to regain it.

  14. Physical signals for protein-DNA recognition

    NASA Astrophysics Data System (ADS)

    Cao, Xiao-Qin; Zeng, Jia; Yan, Hong

    2009-09-01

    This paper discovers consensus physical signals around eukaryotic splice sites, transcription start sites, and replication origin start and end sites on a genome-wide scale based on their DNA flexibility profiles calculated by three different flexibility models. These salient physical signals are localized highly rigid and flexible DNAs, which may play important roles in protein-DNA recognition by the sliding search mechanism. The found physical signals lead us to a detailed hypothetical view of the search process in which a DNA-binding protein first finds a genomic region close to the target site from an arbitrary starting location by three-dimensional (3D) hopping and intersegment transfer mechanisms for long distances, and subsequently uses the one-dimensional (1D) sliding mechanism facilitated by the localized highly rigid DNAs to accurately locate the target flexible binding site within 30 bp (base pair) short distances. Guided by these physical signals, DNA-binding proteins rapidly search the entire genome to recognize a specific target site from the 3D to 1D pathway. Our findings also show that current promoter prediction programs (PPPs) based on DNA physical properties may suffer from lots of false positives because other functional sites such as splice sites and replication origins have similar physical signals as promoters do.

  15. A Systematic Review of the Effectiveness of Physical Education and School Sport Interventions Targeting Physical Activity, Movement Skills and Enjoyment of Physical Activity

    ERIC Educational Resources Information Center

    Dudley, Dean; Okely, Anthony; Pearson, Philip; Cotton, Wayne

    2011-01-01

    This article presents a systematic review of published literature on the effectiveness of physical education in promoting participation in physical activity, enjoyment of physical activity and movement skill proficiency in children and adolescents. The review utilized a literature search, specifically publications listed in Ovid, A+ Education,…

  16. Drug Target Discovery Methods In Targeting Neurotropic Parasitic Amoebae.

    PubMed

    Baig, Abdul Mannan; Waliani, Nuzair; Karim, Saiqa

    2018-02-21

    Neurotropic parasitic amoebal infections have imposed an enormous challenge to chemotherapy in patients who fall victims to the infections caused by them. Conventional antibiotics that are given to treat these infections have a low patient compliance because of the serious adverse effects that are associated with their use. Additionally, the growing incidence of the development of drug resistance by the neurotropic parasites like Naegleria fowleri, Balamuthia mandrillaris, and Acanthamoeba spp has made the drug therapy more challenging. Recent studies have reported some cellular targets in the neurotropic parasitic Acanthamoeba that are used as receptors by human neurotransmitters like acetylcholine. This Viewpoint attempts to highlight the novel methodologies that use drug assays and structural modeling to uncover cellular targets of diverse groups of drugs and the safety issues of the drugs proposed for their use in brain infections caused by the neurotropic parasitic amoebae.

  17. The effects of workplace physical activity interventions in men: a systematic review.

    PubMed

    Wong, Jason Y L; Gilson, Nicholas D; van Uffelen, Jannique G Z; Brown, Wendy J

    2012-07-01

    The workplace is cited as a promising setting for physical activity (PA) promotion, but workplace PA interventions tend not to specifically target men. The aim of this article was to review the literature on workplace PA interventions for men and to identify key issues for future intervention development. Articles targeting PA at the workplace were located through a structured database search. Information on intervention strategies and PA outcomes were extracted. Only 13 studies (10.5%) reviewed focused on men, of which 5 showed significant increases in PA. These studies used generic, multicomponent, health promotion strategies with a variety of timeframes, self-report PA measures, and PA outcomes. The systematic review identified that evidence on the effectiveness of workplace PA interventions for men is equivocal and highlighted methodological concerns. Future research should use reliable and valid measures of PA and interventions that focus specifically on men's needs and PA preferences.

  18. Interventions to Promote Young People's Physical Activity: Issues, Implications and Recommendations for Practice

    ERIC Educational Resources Information Center

    Cale, Lorraine; Harris, Jo

    2006-01-01

    There has been increased interest in the development and implementation of physical activity interventions designed to increase young people's physical activity participation in recent years. This is perhaps founded on concerns over youngsters' physical activity levels and the possible health consequences. School-based interventions are the most…

  19. Physical and mental quality of life in adult patients with haemophilia in Belgium: the impact of financial issues.

    PubMed

    Carvalhosa, A M; Henrard, S; Lambert, C; Hermans, C

    2014-07-01

    In Belgium, where haemophilia affects approximately 1:7000 people (2011), data on patients' quality of life (QoL) is scarce. This project aims to assess physical and mental QoL (P-QoL and M-QoL) simultaneously, and to analyse the influence of different variables on these two aspects of QoL. After Ethics Committee approval, we contacted 84 adult haemophilia A (HA) and haemophilia B (HB) patients, without current inhibitors, on replacement therapy (on-demand or secondary prophylaxis), regularly followed up at our comprehensive treatment centre. Seventy-one (n = 59 HA, n = 12 HB) replied to our questionnaire, which included the SF36v2 QoL assessment forms. We analysed two groups of variables: one including variables previously associated with decreased QoL, and another including variables with unclear impact on QoL (e.g., patients' understanding of haemophilia-related issues, economical concerns). In our population (mean ± SD age: 45.2 ± 14.7 years old), P-QoL appeared more reduced than M-QoL. P-QoL was strongly influenced by the number of arthropathies while M-QoL was primarily affected by patients' concern of personal costs due to haemophilia. Among this latter group, having knowledge of insurance coverage had a positive impact on M-QoL. Scores did not depend on haemophilia type. QoL was impaired in our haemophilia patients. A simultaneous assessment of P-QoL and M-QoL confirmed the benefit of primary prophylaxis in P-QoL, while originally pointing out the major burden of patients' concerns and poor understanding of haemophilia-related economical issues on their M-QoL. This might become a particularly challenging issue in times of financial crisis. © 2013 John Wiley & Sons Ltd.

  20. Expectations Regarding Aging, Physical Activity, and Physical Function in Older Adults

    PubMed Central

    Breda, Aili I.; Watts, Amber S.

    2017-01-01

    Objective: The present study examined how expectations regarding aging (ERA) influence physical activity participation and physical function. Method: We surveyed 148 older adults about their ERA (ERA-38), health-promoting lifestyles (HPLP-II), and self-rated health (RAND-36). We tested the mediating effect of physical activity on the relationships between ERA and physical function. Results: Positive expectations were associated with more engagement in physical activity (B = 0.016, p < .05) and better physical function (B = 0.521, p < .01). Physical activity mediated the relationship between ERA and physical function (B = 5.890, p < .01, indirect effect 0.092, CI = [0.015, 0.239]). Discussion: ERA play an important role in adoption of physically active lifestyles in older adults and may influence health outcomes, such as physical function. Future research should evaluate whether attempts to increase physical activity are more successful when modifications to ERA are also targeted. PMID:28491915

  1. Dating Violence among College Students: Key Issues for College Counselors

    ERIC Educational Resources Information Center

    Murray, Christine E.; Kardatzke, Kerrie N.

    2007-01-01

    The authors present a review of literature examining dating violence among college students. They describe 6 key issues related to dating violence among college students that affect college counselors' work. These key issues relate to the incidence and prevalence of physical, sexual, and psychological violence in college students' dating…

  2. Pre-Med Physics: What and Why.

    ERIC Educational Resources Information Center

    Nichparenko, Sue Broadston

    1985-01-01

    Discusses issues related to the physics concepts/topics needed by health professionals, suggesting that medical students can better understand how the body works by completing meaningful physics courses. Also addresses related concerns expressed by medical students and faculty. A list of 41 physics topics cross-referenced to medical topics is…

  3. Issues Associated with a Hypersonic Maglev Sled

    NASA Technical Reports Server (NTRS)

    Haney, Joseph W.; Lenzo, J.

    1996-01-01

    Magnetic levitation has been explored for application from motors to transportation. All of these applications have been at velocities where the physics of the air or operating fluids are fairly well known. Application of Maglev to hypersonic velocities (Mach greater than 5) presents many opportunities, but also issues that require understanding and resolution. Use of Maglev to upgrade the High Speed Test Track at Holloman Air Force Base in Alamogordo New Mexico is an actual hypersonic application that provides the opportunity to improve test capabilities. However, there are several design issues that require investigation. This paper presents an overview of the application of Maglev to the test track and the issues associated with developing a hypersonic Maglev sled. The focus of this paper is to address the issues with the Maglev sled design, rather than the issues with the development of superconducting magnets of the sled system.

  4. Physics through the 1990s: An overview

    NASA Technical Reports Server (NTRS)

    1986-01-01

    The volume details the interaction of physics and society, and presents a short summary of the progress in the major fields of physics and a summary of the other seven volumes of the Physics through the 1990s series, issues and recommended policy changes are described regarding funding, education, industry participation, small-group university research and large facility programs, government agency programs, and computer database needs. Three supplements report in detail on international issues in physics (the US position in the field, international cooperation and competition-especially on large projects, freedom for scientists, free flow of information, and education of foreign students), the education and supply of physicists (the changes in US physics education, employment and manpower, and demographics of the field), and the organization and support of physics (government, university, and industry research; facilities; national laboratories; and decision making). An executive summary contains recommendations for maintaining excellence in physics. A glossary of scientific terms is appended.

  5. Ethical issues in genetic counselling with special reference to haemoglobinopathies.

    PubMed

    Muthuswamy, Vasantha

    2011-10-01

    Genetic counselling is provided in places where genetic tests are carried out. The process involves pre-test counselling as well as post-test counselling to enable the individuals to face the situation and take appropriate decisions with the right frame of mind. Major ethical principles which govern the attitudes and actions of counsellors include: respect for patient autonomy, non-maleficence, beneficence, or taking action to help benefit others and prevent harm, both physical and mental, and justice, which requires that services be distributed fairly to those in need. Other moral issues include veracity, the duty to disclose information or to be truthful, and respect for patient confidentiality. Nondirective counselling, a hallmark of this profession, is in accordance with the principle of individual autonomy. High prevalence of haemoglobinopathies with availability of good and sensitive carrier detection tests and prenatal diagnostic techniques makes these good candidates for population screening of carriers along with genetic counselling for primary prevention of the disease. Screening of the extended family members of the affected child, high risk communities and general population screening including antenatal women are the main target groups for planning a Haemoglobinopathy control programme. A critical mass of trained genetic counsellors who have understanding of the ethical issues and its appropriate handling with the required sensitivity is needed in India.

  6. Physical and mental health perspectives of first year undergraduate rural university students.

    PubMed

    Hussain, Rafat; Guppy, Michelle; Robertson, Suzanne; Temple, Elizabeth

    2013-09-15

    University students are often perceived to have a privileged position in society and considered immune to ill-health and disability. There is growing evidence that a sizeable proportion experience poor physical health, and that the prevalence of psychological disorders is higher in university students than their community peers. This study examined the physical and mental health issues for first year Australian rural university students and their perception of access to available health and support services. Cross-sectional study design using an online survey form based on the Adolescent Screening Questionnaire modeled on the internationally recognised HEADSS survey tool. The target audience was all first-year undergraduate students enrolled in an on-campus degree program. The response rate was 41% comprising 355 students (244 females, 111 males). Data was analysed using standard statistical techniques including descriptive and inferential statistics; and thematic analysis of the open-ended responses. The mean age of the respondents was 20.2 years (SD 4.8). The majority of the students lived in on-campus residential college style accommodation, and a third combined part-time paid work with full-time study. Most students reported being in good physical health. However, on average two health conditions were reported over the past six months, with the most common being fatigue (56%), frequent headaches (26%) and allergies (24%). Mental health problems included anxiety (25%), coping difficulties (19.7%) and diagnosed depression (8%). Most respondents reported adequate access to medical doctors and support services for themselves (82%) and friends (78%). However the qualitative comments highlighted concerns about stigma, privacy and anonymity in seeking counselling. The present study adds to the limited literature of physical and mental health issues as well as barriers to service utilization by rural university students. It provides useful baseline data for the

  7. Physical and mental health perspectives of first year undergraduate rural university students

    PubMed Central

    2013-01-01

    Background University students are often perceived to have a privileged position in society and considered immune to ill-health and disability. There is growing evidence that a sizeable proportion experience poor physical health, and that the prevalence of psychological disorders is higher in university students than their community peers. This study examined the physical and mental health issues for first year Australian rural university students and their perception of access to available health and support services. Methods Cross-sectional study design using an online survey form based on the Adolescent Screening Questionnaire modeled on the internationally recognised HEADSS survey tool. The target audience was all first-year undergraduate students enrolled in an on-campus degree program. The response rate was 41% comprising 355 students (244 females, 111 males). Data was analysed using standard statistical techniques including descriptive and inferential statistics; and thematic analysis of the open-ended responses. Results The mean age of the respondents was 20.2 years (SD 4.8). The majority of the students lived in on-campus residential college style accommodation, and a third combined part-time paid work with full-time study. Most students reported being in good physical health. However, on average two health conditions were reported over the past six months, with the most common being fatigue (56%), frequent headaches (26%) and allergies (24%). Mental health problems included anxiety (25%), coping difficulties (19.7%) and diagnosed depression (8%). Most respondents reported adequate access to medical doctors and support services for themselves (82%) and friends (78%). However the qualitative comments highlighted concerns about stigma, privacy and anonymity in seeking counselling. Conclusions The present study adds to the limited literature of physical and mental health issues as well as barriers to service utilization by rural university students. It

  8. Physics-based Detection of Subpixel Targets in Hyperspectral Imagery

    DTIC Science & Technology

    2007-01-01

    Learning Vector Quantization LWIR ...Wave Infrared ( LWIR ) from 7.0 to 15.0 microns regions as well. At these wavelengths, emissivity dominates the spectral signature. Emissivity is...object emits instead of reflects. Initial work has already been finished applying the hybrid detectors to LWIR sensors [13]. However, target

  9. Physical Activity Helps Seniors Stay Mobile

    MedlinePlus

    ... Subscribe July 2014 Print this issue Health Capsule Physical Activity Helps Seniors Stay Mobile En español Send us your comments A carefully structured, moderate physical activity program helped vulnerable older people maintain their mobility. ...

  10. Physical activity and cancer prevention : pathways and targets for intervention.

    PubMed

    Rogers, Connie J; Colbert, Lisa H; Greiner, John W; Perkins, Susan N; Hursting, Stephen D

    2008-01-01

    The prevalence of obesity, an established epidemiological risk factor for many cancers, has risen steadily for the past several decades in the US and many other countries. Particularly alarming are the increasing rates of obesity among children, portending continuing increases in the rates of obesity and obesity-related cancers for many years to come. Modulation of energy balance, via increased physical activity, has been shown in numerous comprehensive epidemiological reviews to reduce cancer risk. Unfortunately, the effects and mechanistic targets of physical activity interventions on the carcinogenesis process have not been thoroughly characterized. Studies to date suggest that exercise can exert its cancer-preventive effects at many stages during the process of carcinogenesis, including both tumour initiation and progression. As discussed in this review, exercise may be altering tumour initiation events by modifying carcinogen activation, specifically by enhancing the cytochrome P450 system and by enhancing selective enzymes in the carcinogen detoxification pathway, including, but not limited to, glutathione-S-transferases. Furthermore, exercise may reduce oxidative damage by increasing a variety of anti-oxidant enzymes, enhancing DNA repair systems and improving intracellular protein repair systems. In addition to altering processes related to tumour initiation, exercise may also exert a cancer-preventive effect by dampening the processes involved in the promotion and progression stages of carcinogenesis, including scavenging reactive oxygen species (ROS); altering cell proliferation, apoptosis and differentiation; decreasing inflammation; enhancing immune function; and suppressing angiogenesis. A paucity of data exists as to whether exercise may be working as an anti-promotion strategy via altering ROS in initiated or preneoplastic models; therefore, no conclusions can be made about this possible mechanism. The studies directly examining cell proliferation

  11. The Case for Daily Physical Education

    ERIC Educational Resources Information Center

    Lynn, Susan

    2007-01-01

    According to a recent study, only 56 percent of high school students participate in physical education, and the percentage of schools requiring physical education has progressively dropped. The goal of providing daily physical education to all K-12 students in the United States presents challenges such as budgetary issues, less time for other…

  12. Exercise Prescription for Physical Fitness.

    ERIC Educational Resources Information Center

    Pollock, Michael L.; And Others

    1995-01-01

    Examines current guidelines for physical fitness, noting issues that may influence the updating of the American College of Sports Medicine exercise statement. Differences between exercise prescription for fitness and physical activity for health are discussed, noting the importance of designing individualized programs with appropriate levels of…

  13. Children with Cancer: School Related Issues

    ERIC Educational Resources Information Center

    Gartin, Barbara C.; Murdick, Nikki L.

    2009-01-01

    School gives purpose to a student's life. Today, students with cancer and cancer survivors are encouraged to continue their educational experiences to maintain a sense of normalcy. This manuscript discusses the research findings on medical, physical, and cognitive issues that students with cancer and cancer survivors may encounter in their…

  14. Environmental influences on physical activity in rural Midwestern adults: a qualitative approach.

    PubMed

    Chrisman, Matthew; Nothwehr, Faryle; Yang, Ginger; Oleson, Jacob

    2015-01-01

    Qualitative research can be used to examine multiple factors associated with physical activity and help practitioners identify language used by the rural adult population when discussing this behavior. Three focus groups were conducted among 19 residents of multiple towns in a rural Midwestern county to examine the language and influences on rural physical activity. Focus group members were asked to define physical activity, exercise, community, and neighborhood. They were asked about the activities they engaged in and facilitators and barriers to those activities. A guidebook was developed to capture major themes and common patterns that emerged in the responses to the topics discussed. The data were reviewed for repeated statements and points that were agreed on by multiple participants. Important factors associated with physical activity include the importance of social support and modeling physical activity behavior. Also, the influence of pets and children was important for engaging these adults in physical activity. The focus group members engaged in walking and bicycling in their neighborhood streets and community trails, and desired to see community buildings be open to the public for exercise. This study revealed contextual issues and culturally relevant language for practitioners to use in tailoring physical activity measurement tools or designing interventions for a rural adult population. Social support (specifically, seeing others being active and using pets as motivators for being active) and policy attitudes may be targeted for interventions to increase physical activity in rural adults. © 2014 Society for Public Health Education.

  15. Environmental Influences on Physical Activity in Rural Midwestern Adults: A Qualitative Approach

    PubMed Central

    Chrisman, Matthew; Nothwehr, Faryle; Yang, Ginger; Oleson, Jacob

    2014-01-01

    Qualitative research can be used to examine multiple factors associated with physical activity and help practitioners identify language used by the rural adult population when discussing this behavior. Three focus groups were conducted among 19 residents of multiple towns in a rural Midwestern county to examine the language and influences on rural physical activity. Focus group members were asked to define physical activity, exercise, community, and neighborhood. They were asked about the activities they engaged in and facilitators and barriers to those activities. A guidebook was developed to capture major themes and common patterns that emerged in the responses to the topics discussed. The data were reviewed for repeated statements and points that were agreed on by multiple participants. Important factors associated with physical activity include the importance of social support and modeling physical activity behavior. Also, the influence of pets and children was important for engaging these adults in physical activity. The focus group members engaged in walking and bicycling in their neighborhood streets and community trails, and desired to see community buildings be open to the public for exercise. This study revealed contextual issues and culturally relevant language for practitioners to use in tailoring physical activity measurement tools or designing interventions for a rural adult population. Social support (specifically, seeing others being active and using pets as motivators for being active) and policy attitudes may be targeted for interventions to increase physical activity in rural adults. PMID:24662894

  16. Targeted diphtheria toxin to treat BPDCN.

    PubMed

    FitzGerald, David J

    2014-07-17

    In this issue of Blood, Frankel et al describe a novel treatment of blastic plasmacytoid dendritic cell neoplasm (BPDCN) using an engineered version of diphtheria toxin that is targeted to malignant cells via a fusion with interleukin (IL)3 (see panel A).

  17. Community-Based Culturally Preferred Physical Activity Intervention Targeting Populations at High Risk for Type 2 Diabetes: Results and Implications.

    PubMed

    Rowan, Chip P; Riddell, Michael C; Gledhill, Norman; Jamnik, Veronica K

    2016-12-01

    In Canada, an ageing population, obesity rates and high risk among certain ethnocultural populations are driving diabetes prevalence. Given the burden associated with type 2 diabetes and its link to modifiable risk factors, this study aimed to implement culturally preferred physical activities at the community level, targeting individuals at high risk for type 2 diabetes. Glycated hemoglobin (A1C) levels were used to detect potential improvements in glycemic control. Participants were screened for diabetes risk using a questionnaire and capillary point-of-care A1C blood testing. Participants were offered community-based physical activity classes 2 to 3 times per week for 6 months. A subset of participants (n=84) provided additional measurements. In total, 718 subjects were reached during recruitment. Substantial participant dropout took place, and 487 participants were exposed to the intervention. Among those who participated in the physical activity and provided follow up, mean A1C levels were reduced by 0.17 (p=0.002) after 3 months (n=84) and by 0.06 (p=0.35; n=49) after 6 months. The homeostatic model assessment (HOMA-beta) showed a significant improvement of 23.6% after 3 months (n=20; p=0.03) and 45.2% after 6 months (n=12; p=0.02). Resting systolic blood pressure and diastolic blood pressure plus combined hand-grip strength improved after 6 months (n=12). Implementation of this community-based, culturally preferred physical activity program presented several challenges and was associated with significant participant dropout. After considering participant dropout, the relatively small group who participated and provided follow-up measures showed improvements various physiologic measures. Despite efforts to enhance accessibility, it appears that several barriers to physical activity participation remain and need to be explored to enhance the success of future programs. Copyright © 2016 Canadian Diabetes Association. Published by Elsevier Inc. All rights

  18. A small molecule nanodrug consisting of amphiphilic targeting ligand-chemotherapy drug conjugate for targeted cancer therapy.

    PubMed

    Mou, Quanbing; Ma, Yuan; Zhu, Xinyuan; Yan, Deyue

    2016-05-28

    Targeted drug delivery is a broadly applicable approach for cancer therapy. However, the nanocarrier-based targeted delivery system suffers from batch-to-batch variation, quality concerns and carrier-related toxicity issues. Thus, to develop a carrier-free targeted delivery system with nanoscale characteristics is very attractive. Here, a novel targeting small molecule nanodrug self-delivery system consisting of targeting ligand and chemotherapy drug was constructed, which combined the advantages of small molecules and nano-assemblies together and showed excellent targeting ability and long blood circulation time with well-defined structure, high drug loading ratio and on-demand drug release behavior. As a proof-of-concept, lactose (Lac) and doxorubicin (DOX) were chosen as the targeting ligand and chemotherapy drug, respectively. Lac and DOX were conjugated through a pH-responsive hydrazone group. For its intrinsic amphiphilic property, Lac-DOX conjugate could self-assemble into nanoparticles in water. Both in vitro and in vivo assays indicated that Lac-DOX nanoparticles exhibited enhanced anticancer activity and weak side effects. This novel active targeting nanodrug delivery system shows great potential in cancer therapy. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. Rural-Urban Differences in Physical Activity, Physical Fitness, and Overweight Prevalence of Children

    ERIC Educational Resources Information Center

    Joens-Matre, Roxane R.; Welk, Gregory J.; Calabro, Miguel A.; Russell, Daniel W.; Nicklay, Elizabeth; Hensley, Larry D.

    2008-01-01

    Context: The increasing prevalence of overweight in youth has been well chronicled, but less is known about the unique patterns and risks that may exist in rural and urban environments. A better understanding of possible rural-urban differences in physical activity profiles may facilitate the development of more targeted physical activity…

  20. PREFACE: 31st European Physical Society Conference on Plasma Physics

    NASA Astrophysics Data System (ADS)

    Dendy, Richard

    2004-12-01

    This special issue of Plasma Physics and Controlled Fusion comprises refereed papers contributed by invited speakers at the 31st European Physical Society Conference on Plasma Physics. The conference was jointly hosted by the Rutherford Appleton Laboratory, by the EURATOM/UKAEA Fusion Association and by Imperial College London, where it took place from 28 June to 2 July 2004. The overall agenda for this conference was set by the Board of the Plasma Physics Division of the European Physical Society, chaired by Friedrich Wagner (MPIPP, Garching) and his successor Jo Lister (CRPP, Lausanne). It built on developments in recent years, by further increasing the scientific diversity of the conference programme, whilst maintaining its depth and quality. A correspondingly diverse Programme Committee was set up, whose members are listed below. The final task of the Programme Committee has been the preparation of this special issue. In carrying out this work, as in preparing the scientific programme of the conference, the Programme Committee formed specialist subcommittees representing the different fields of plasma science. The chairmen of these subcommittees, in particular, accepted a very heavy workload on behalf of their respective research communities. It is a great pleasure to take this opportunity to thank: Emilia R Solano (CIEMAT, Madrid), magnetic confinement fusion; Jürgen Meyer-ter-Vehn (MPQ, Garching), laser-plasma interaction and beam plasma physics; and Jean-Luc Dorier (CRPP, Lausanne), dusty plasmas. The relatively few papers in astrophysical and basic plasma physics were co-ordinated by a small subcommittee which I led. Together with Peter Norreys (RAL, Chilton), we five constitute the editorial team for this special issue. The extensive refereeing load, compressed into a short time interval, was borne by the Programme Committee members and by many other experts, to whom this special issue owes much. We are also grateful to the Local Organizing Committee

  1. Physical education issues for students with autism: school nurse challenges.

    PubMed

    Rutkowski, Elaine M; Brimer, Debbie

    2014-08-01

    Extant studies indicate persons with autism have difficulties in social interaction, verbal and nonverbal communication, repetitive behaviors, and poor ability to generalize learned skills. Obesity has also been identified as significantly affecting children with autism spectrum disorders (ASD). Negative experience in physical education (PE) may be the antecedent behavior to lack of activities that are mediators to sedentary lifestyles and contributors to the chronic illnesses associated with overweight and obesity. Students with ASD often cannot perform required activities to meet required PE standards. It is imperative school nurses be aware of the many challenges students with ASD bring into a PE class. School nurses provide education for the members of the school community, including the Individualized Education Plan team, regarding the need for attention to limitations, including physical activity, of students with ASD. © The Author(s) 2013.

  2. Intermediaries for youth: a vital target audience.

    PubMed

    1997-01-01

    Worldwide, youth are recognized as a key target audience for HIV/STD awareness and prevention campaigns. Rural young people, who often have less access to information and prevention tools than urban youth, may be particularly vulnerable to HIV/STD infection. Many initiatives have been organized by nongovernmental organizations, governments, churches, and other organizations to help youth. However, parents, relatives, guardians, teachers, church and youth leaders, social workers, and other adults in a position to influence youth must also be helped to undertake the role of an intermediary between youth and HIV/STD interventions and other youth-oriented programs. In training adults to openly address sexual and reproductive health issues with adolescents, adults must first be encouraged to feel comfortable about discussing such issues among themselves. Intermediaries and how to target them are discussed.

  3. Laser ``M'egajoule'' cryogenic target program: from target fabrication to conformation of the deuterium-tritium ice layer

    NASA Astrophysics Data System (ADS)

    Collier, Rémy; Durut, Frédéric; Reneaume, Benoît; Chicane, Cédric; Théobald, Marc; Breton, Olivier; Martin, Michel; Fleury, Emmanuel; Vincent-Viry, Olivier; Bachelet, Franck; Jeannot, Laurent; Geoffray, Isabelle; Botrel, Ronan; Dauteuil, Christophe; Hermerel, Cyril; Choux, Alexandre; Bednarczyk, Sophie; Legaie, Olivier

    2008-11-01

    For the French inertial confinement fusion (ICF) experiments, cryogenic target assemblies (CTAs) for the LMJ program are manufactured and filled at CEA Valduc (Dijon) in the cryogenic targets filling station (IRCC). They will be moved at about 20 K into a transport cryostat for cryogenic targets and will be driven from CEA/Valduc to CEA/CESTA (Bordeaux). Cryogenic targets will then be transferred by several cryogenic grippers on the cryogenic target positioner before shots. The CTA has to meet severe specifications and involves a lot of challenging tasks for its manufacture. To fill CTAs by permeation with deuterium-tritium (DT), the IRCC need to meet strict thermal, mechanical and dimensional specifications. To obtain a good combustion yield, a very homogenous DT ice layer and very smooth roughness at 1.5 K below the DT triple point are also required. This paper deals with the up to date main issues in the different fields of the LMJ cryogenic target program.

  4. Youth Physical Fitness: Ten Key Concepts

    ERIC Educational Resources Information Center

    Corbin, Charles B.; Welk, Gregory J.; Richardson, Cheryl; Vowell, Catherine; Lambdin, Dolly; Wikgren, Scott

    2014-01-01

    The promotion of physical fitness has been a key objective of physical education for more than a century. During this period, physical education has evolved to accommodate changing views on fitness and health. The purpose of this article is to discuss issues with fitness assessment and fitness education central to the new Presidential Youth…

  5. Report of the APS Ad-Hoc Committee on LGBT Issues - Presentation of Findings and Recommendations

    NASA Astrophysics Data System (ADS)

    Falk, Michael

    In 2014 the Executive Officer of the American Physical Society (APS), Kate Kirby, created an Ad-Hoc Committee on LGBT Issues (C-LGBT) charged with reporting on the obstacles to inclusion of LGBT physicists, a term which for the purpose of this report refers to persons who self-identify as lesbian, gay, bisexual, transgender, queer, questioning, intersex, or asexual, as well as other sexual and gender minorities. The full charge was as follows: ``The committee will advise the APS on the current status of LGBT issues in physics, provide recommendations for greater inclusion, and engage physicists in laying the foundation for a more inclusive physics community. ?More specifically, the committee will investigate LGBT representation in physics, assess the educational and professional climate in physics, recommend changes in policies and practices that impact LGBT physicists, and address other issues that affect inclusion.'' We will present the findings and recommendations of the C-LGBT final report, and a panel discussion will be held following the presentation to discuss the future of APS efforts toward LGBT inclusion in physics.

  6. Report of the APS Ad-Hoc Committee on LGBT Issues - Presentation of Findings and Recommendations

    NASA Astrophysics Data System (ADS)

    Long, Elena

    2016-03-01

    In 2014 the Executive Officer of the American Physical Society (APS), Kate Kirby, created an Ad-Hoc Committee on LGBT Issues (C-LGBT) charged with reporting on the obstacles to inclusion of LGBT physicists, a term which for the purpose of this report refers to persons who self-identify as lesbian, gay, bisexual, transgender, queer, questioning, intersex, or asexual, as well as other sexual and gender minorities. The full charge was as follows: ``The committee will advise the APS on the current status of LGBT issues in physics, provide recommendations for greater inclusion, and engage physicists in laying the foundation for a more inclusive physics community? More specifically, the committee will investigate LGBT representation in physics, assess the educational and professional climate in physics, recommend changes in policies and practices that impact LGBT physicists, and address other issues that affect inclusion.'' We will present the findings and recommendations of the C-LGBT final report, and a panel discussion will be held following the presentation to discuss the future of APS efforts toward LGBT inclusion in physics.

  7. Fundamental physics issues of multilevel logic in developing a parallel processor.

    NASA Astrophysics Data System (ADS)

    Bandyopadhyay, Anirban; Miki, Kazushi

    2007-06-01

    In the last century, On and Off physical switches, were equated with two decisions 0 and 1 to express every information in terms of binary digits and physically realize it in terms of switches connected in a circuit. Apart from memory-density increase significantly, more possible choices in particular space enables pattern-logic a reality, and manipulation of pattern would allow controlling logic, generating a new kind of processor. Neumann's computer is based on sequential logic, processing bits one by one. But as pattern-logic is generated on a surface, viewing whole pattern at a time is a truly parallel processing. Following Neumann's and Shannons fundamental thermodynamical approaches we have built compatible model based on series of single molecule based multibit logic systems of 4-12 bits in an UHV-STM. On their monolayer multilevel communication and pattern formation is experimentally verified. Furthermore, the developed intelligent monolayer is trained by Artificial Neural Network. Therefore fundamental weak interactions for the building of truly parallel processor are explored here physically and theoretically.

  8. Origins of life: a problem for physics, a key issues review

    NASA Astrophysics Data System (ADS)

    Imari Walker, Sara

    2017-09-01

    The origins of life stands among the great open scientific questions of our time. While a number of proposals exist for possible starting points in the pathway from non-living to living matter, these have so far not achieved states of complexity that are anywhere near that of even the simplest living systems. A key challenge is identifying the properties of living matter that might distinguish living and non-living physical systems such that we might build new life in the lab. This review is geared towards covering major viewpoints on the origin of life for those new to the origin of life field, with a forward look towards considering what it might take for a physical theory that universally explains the phenomenon of life to arise from the seemingly disconnected array of ideas proposed thus far. The hope is that a theory akin to our other theories in fundamental physics might one day emerge to explain the phenomenon of life, and in turn finally permit solving its origins.

  9. Cultural Issues in Syrian EFL Classrooms

    ERIC Educational Resources Information Center

    Ulum, Ömer Gökhan

    2016-01-01

    Whether we should teach culture or not when we teach English as a Foreign Language has been great concern for a long time. Which one should be contained in EFL course books? The culture of the target language or the own culture of EFL learners? Regarding this issue, many researchers have a diversity of opinions, however; this study was conducted…

  10. Path forward: emerging issues and challenges.

    PubMed

    Gillen, Matt; Gittleman, Janie L

    2010-06-01

    The NIOSH Construction Program worked with industry stakeholders to develop a National Occupational Safety and Health Construction Agenda to target future research and activities. The Program and its partners are also cognizant that new developments can emerge over time and that research can play an important role in helping to understand and address these emerging issues. Examples of emerging issues relevant to construction safety and health are described. These include: (a) climate change and energy considerations; (b) green construction developments and opportunities; (c) new materials; (d) changes in industry structure and practice; (e) workforce developments and disparities; (f) injury underreporting and cost and risk shifting; and (g) increased interest in addressing root causes. Responding to emerging issues while maintaining a focus on fundamental longstanding issues represents an ongoing challenge for researchers and industry organizations. Additional research to understand the diffusion and adoption of research by the industry is also needed. Research accomplished to date provides a strong foundation for addressing future industry needs and trends. (c) 2010 Elsevier Ltd. All rights reserved.

  11. ANITA (Advanced Network for Isotope and TArget laboratories) - The urgent need for a European target preparation network

    NASA Astrophysics Data System (ADS)

    Schumann, Dorothea; Sibbens, Goedele; Stolarz, Anna; Eberhardt, Klaus; Lommel, Bettina; Stodel, Christelle

    2018-05-01

    A wide number of research fields in the nuclear sector requires high-quality and well-characterized samples and targets. Currently, only a few laboratories own or have access to the equipment allowing fulfilling such demands. Coordination of activities and sharing resources is therefore mandatory to meet the increasing needs. This very urgent issue has now been addressed by six European target laboratories with an initiative called ANITA (Advanced Network for Isotope and TArget laboratories). The global aim of ANITA is to establish an overarching research infrastructure service for isotope and target production and develop a tight cooperation between the target laboratories in Europe in order to transfer the knowledge and improve the production techniques of well-characterized samples and targets. Moreover, the interaction of the target producers with the users shall be encouraged and intensified to deliver tailor-made targets best-suited to the envisaged experiments. For the realization of this ambitious goal, efforts within the European Commission and strong support by the target-using communities will be necessary. In particular, an appropriate funding instrument has to be found and applied, enabling ANITA to develop from an initiative employed by the interested parties to a real coordination platform.

  12. Sickle red cell adhesion: many issues and some answers.

    PubMed

    Kaul, D K

    2008-01-01

    Among multiple pathologies associated with sickle cell disease, sickle red cell-endothelial interaction has been implicated as a potential initiating mechanism in vaso-occlusive events that characterize this disease. Vast literature exists on various aspects of sickle red cell adhesion, but many issues remain unresolved, especially pertaining to the role of sickle red cell heterogeneity, the relative role of multiple adhesion mechanisms and targets of antiadhesive therapy. This review briefly analyzes these issues.

  13. A review of the ligands and related targeting strategies for active targeting of paclitaxel to tumours.

    PubMed

    Li, Juan; Wang, Fengshan; Sun, Deqing; Wang, Rongmei

    2016-08-01

    It has been 30 years since the discovery of the anti-tumour property of paclitaxel (PTX), which has been successfully applied in clinic for the treatment of carcinomas of the lungs, breast and ovarian. However, PTX is poorly soluble in water and has no targeting and selectivity to tumour tissue. Recent advances in active tumour targeting of PTX delivery vehicles have addressed some of the issues related to lack of solubility in water and non-specific toxicities associated with PTX. These PTX delivery vehicles are designed for active targeting to specific cancer cells by the addition of ligands for recognition by specific receptors/antigens on cancer cells. This article will focus on various ligands and related targeting strategies serving as potential tools for active targeting of PTX to tumour tissues, illustrating their use in different tumour models. This review also highlights the need of further studies on the discovery of receptors in different cells of specific organ and ligands with binding efficiency to these specific receptors.

  14. Influence of Human Factor Issues on Patient-Centered mHealth Apps' Impact; Where Do We Stand?

    PubMed

    Wildenbos, G A; Peute, L W; Jaspers, M W M

    2016-01-01

    This paper discusses the preliminary results of a literature review on studies published in 2014-2015 concerning patient-centered mHealth applications' (apps) impact. Abstracts were included when they described a mHealth app targeted at patients and reported on the effects of this app on patient care. From a total of 559 potentially relevant articles, 17 papers were finally included. Nine studies reported a positive impact of the patient-centered mHealth app on patient care; 4 of these studies were randomized controlled trials. Measured impacts in the 17 studies focused on improving patients' physical activity, self-efficacy and medication adherence. Human factors issues potentially mediating these effects were discussed in all studies. Transitions in the interaction between healthcare providers and their patients were most often discussed as influencing the impact of the mHealth app. More research is needed, focussing on human issues mediating the effect of patient-centered mHealth apps to precipitate knowledge on the effectiveness of mHealth. This research should preferably be guided by socio-technical models.

  15. Notice of omission in the printed edition of Volume 58, Issue 1 Notice of omission in the printed edition of Volume 58, Issue 1

    NASA Astrophysics Data System (ADS)

    2013-01-01

    Due to a production error, the article 'Corrigendum: Task-based evaluation of segmentation algorithms for diffusion-weighted MRI without using a gold standard' by Abhinav K Jha, Matthew A Kupinski, Jeffrey J Rodriguez, Renu M Stephen and Alison T Stopeck was duplicated and the article 'Corrigendum: Complete electrode model in EEG: relationship and differences to the point electrode model' by S Pursiainen, F Lucka and C H Wolters was omitted in the print version of Physics in Medicine & Biology, volume 58, issue 1. The online versions of both articles are not affected. The article 'Corrigendum: Complete electrode model in EEG: relationship and differences to the point electrode model' by S Pursiainen, F Lucka and C H Wolters will be included in the print version of this issue (Physics in Medicine & Biology, volume 58, issue 2.) We apologise unreservedly for this error. Jon Ruffle Publisher

  16. Target Fishing for Chemical Compounds using Target-Ligand Activity data and Ranking based Methods

    PubMed Central

    Wale, Nikil; Karypis, George

    2009-01-01

    In recent years the development of computational techniques that identify all the likely targets for a given chemical compound, also termed as the problem of Target Fishing, has been an active area of research. Identification of likely targets of a chemical compound helps to understand problems such as toxicity, lack of efficacy in humans, and poor physical properties associated with that compound in the early stages of drug discovery. In this paper we present a set of techniques whose goal is to rank or prioritize targets in the context of a given chemical compound such that most targets that this compound may show activity against appear higher in the ranked list. These methods are based on our extensions to the SVM and Ranking Perceptron algorithms for this problem. Our extensive experimental study shows that the methods developed in this work outperform previous approaches by 2% to 60% under different evaluation criterions. PMID:19764745

  17. Engaging Students in Physical Education: Key Challenges and Opportunities for Physical Educators in Urban Settings

    ERIC Educational Resources Information Center

    Sliwa, Sarah; Nihiser, Allison; Lee, Sarah; McCaughtry, Nathan; Culp, Brian; Michael, Shannon

    2017-01-01

    In October 2009, "JOPERD" published a special issue about "Engaging Urban Youths in Physical Education and Physical Activity." Seven years later, many of the considerations mentioned remain relevant, such as large class sizes, limited access to equipment, and the lack of a dedicated gymnasium or outdoor space. These structural…

  18. Wireless physical layer security

    NASA Astrophysics Data System (ADS)

    Poor, H. Vincent; Schaefer, Rafael F.

    2017-01-01

    Security in wireless networks has traditionally been considered to be an issue to be addressed separately from the physical radio transmission aspects of wireless systems. However, with the emergence of new networking architectures that are not amenable to traditional methods of secure communication such as data encryption, there has been an increase in interest in the potential of the physical properties of the radio channel itself to provide communications security. Information theory provides a natural framework for the study of this issue, and there has been considerable recent research devoted to using this framework to develop a greater understanding of the fundamental ability of the so-called physical layer to provide security in wireless networks. Moreover, this approach is also suggestive in many cases of coding techniques that can approach fundamental limits in practice and of techniques for other security tasks such as authentication. This paper provides an overview of these developments.

  19. Wireless physical layer security.

    PubMed

    Poor, H Vincent; Schaefer, Rafael F

    2017-01-03

    Security in wireless networks has traditionally been considered to be an issue to be addressed separately from the physical radio transmission aspects of wireless systems. However, with the emergence of new networking architectures that are not amenable to traditional methods of secure communication such as data encryption, there has been an increase in interest in the potential of the physical properties of the radio channel itself to provide communications security. Information theory provides a natural framework for the study of this issue, and there has been considerable recent research devoted to using this framework to develop a greater understanding of the fundamental ability of the so-called physical layer to provide security in wireless networks. Moreover, this approach is also suggestive in many cases of coding techniques that can approach fundamental limits in practice and of techniques for other security tasks such as authentication. This paper provides an overview of these developments.

  20. Wireless physical layer security

    PubMed Central

    Schaefer, Rafael F.

    2017-01-01

    Security in wireless networks has traditionally been considered to be an issue to be addressed separately from the physical radio transmission aspects of wireless systems. However, with the emergence of new networking architectures that are not amenable to traditional methods of secure communication such as data encryption, there has been an increase in interest in the potential of the physical properties of the radio channel itself to provide communications security. Information theory provides a natural framework for the study of this issue, and there has been considerable recent research devoted to using this framework to develop a greater understanding of the fundamental ability of the so-called physical layer to provide security in wireless networks. Moreover, this approach is also suggestive in many cases of coding techniques that can approach fundamental limits in practice and of techniques for other security tasks such as authentication. This paper provides an overview of these developments. PMID:28028211

  1. Adaptive optics to enhance target recognition

    NASA Astrophysics Data System (ADS)

    McAulay, Alastair D.

    2012-06-01

    Target recognition can be enhanced by reducing image degradation due to atmospheric turbulence. This is accomplished by an adaptive optic system. We discuss the forms of degradation when a target is viewed through the atmosphere1: scintillation from ground targets on a hot day in visible or infrared light; beam spreading and wavering around in time; atmospheric turbulence caused by motion of the target or by weather. In the case of targets we can use a beacon laser that reflects back from the target into a wavefront detector to measure the effects of turbulence on propagation to and from the target before imaging.1 A deformable mirror then corrects the wavefront shape of the transmitted, reflected or scattered data for enhanced imaging. Further, recognition of targets is enhanced by performing accurate distance measurements to localized parts of the target using lidar. Distance is obtained by sending a short pulse to the target and measuring the time for the pulse to return. There is inadequate time to scan the complete field of view so that the beam must be steered to regions of interest such as extremities of the image during image recognition. Distance is particularly valuable to recognize fine features in range along the target or when segmentation is required to separate a target from background or from other targets. We discuss the issues involved.

  2. Special Issue Busing. NCRIEEO Newsletter, Volume 3, Number 2, May 1972.

    ERIC Educational Resources Information Center

    Gordon, Edmund W., Ed.

    Contents of this issue of the NCRIEEO Newsletter include the following articles: (1) "Editor's commentary: background to the issue," by Edmund Gordon, which puts busing into perspective as an important educational resource--like physical facilities, instructional materials, and teachers--to be used to achieve educational and social…

  3. Mothers' intentions to support children's physical activity related to attention and implicit agreement with advertisements.

    PubMed

    Berry, Tanya R; Craig, Cora L; Faulkner, Guy; Latimer, Amy; Rhodes, Ryan; Spence, John C; Tremblay, Mark S

    2014-02-01

    ParticipACTION's Think Again campaign targeted mothers who think their children are sufficiently active, yet whose children do not achieve recommended amounts of physical activity. This research examined the relationship of mothers' intentions to support children's physical activity with explicit believability and implicit agreement with the Think Again campaign message, attention paid to the advertisement, involvement with the issue, concern regarding children's inactivity, and attitudes. Participants were mothers from Edmonton, Canada (N = 102) who viewed one Think Again advertisement then completed a measure of implicit agreement with the campaign message and questionnaires. The mothers who paid attention to the message and were concerned for their own children were more likely to intend to act on campaign messages. The majority of participants implicitly agreed that children's physical inactivity was a problem, but there was less agreement that physical inactivity was a problem for their own children. Participants automatically tended to agree with campaign messages when the focus was on children in general, but there was greater disagreement when asked about participant's own children. Why most mothers were not in agreement with the reality of how much physical activity their children needs remains to be determined.

  4. Physical Assault of School Personnel

    ERIC Educational Resources Information Center

    Kajs, Lawrence T.; Schumacher, Gary; Vital, Cheryl A.

    2014-01-01

    Physical assault against school personnel is a serious problem, although not highly publicized. This workplace violence can result in debilitating injury to school employees along with major monetary costs. This article looks at legal issues that address physical assault against school personnel as well as the roles professional associations have…

  5. Ethics in Physical and Sport Education.

    ERIC Educational Resources Information Center

    Spencer, Albert F.

    1996-01-01

    This article focuses on ways to integrate ethical issues in physical and sport education into professional action without involving institutional control, considering an individual approach to teaching-coaching practices that builds students' ethical decision making skills and develops character. Issues for group discussion and individual…

  6. Physical Education Issues for Students with Autism: School Nurse Challenges

    ERIC Educational Resources Information Center

    Rutkowski, Elaine M.; Brimer, Debbie

    2014-01-01

    Extant studies indicate persons with autism have difficulties in social interaction, verbal and nonverbal communication, repetitive behaviors, and poor ability to generalize learned skills. Obesity has also been identified as significantly affecting children with autism spectrum disorders (ASD). Negative experience in physical education (PE) may…

  7. Physical Disabilities: Education and Related Services, Fall 1999-Spring 2000.

    ERIC Educational Resources Information Center

    Kulik, Barbara J., Ed.

    2000-01-01

    These two journal issues discuss topics relating to the physical and health disabilities of children and adults. The first issue contains the following articles: (1) "Position Statement on Specialized Health Care Procedures," by the Council for Exceptional Children's Division on Physical and Health Disabilities that calls for all…

  8. Alcohol and the Physically Impaired: Special Focus.

    ERIC Educational Resources Information Center

    Boros, Alexander, Ed.

    1989-01-01

    The articles in this special issue explore the connections between the dual disabilities of alcohol abuse and physical impairment, and reflect progress made in exploring the causes and treatments of alcohol abuse among the physically impaired. Selected articles include: "Results of a Model Intervention Program for Physically Impaired…

  9. Uncovering the Secrets: Homophobia in Physical Education

    ERIC Educational Resources Information Center

    Ayvazo, Shiri; Sutherland, Sue

    2009-01-01

    Studies examining the discourse on issues related to sexual orientation in physical education reveal that the physical education setting is an environment where heterosexism, heteronormativity, and homophobia subsist fervently. The purpose of this article is to review the growing research that has been conducted on homophobia in physical education…

  10. Target discrimination strategies in optics detection

    NASA Astrophysics Data System (ADS)

    Sjöqvist, Lars; Allard, Lars; Henriksson, Markus; Jonsson, Per; Pettersson, Magnus

    2013-10-01

    Detection and localisation of optical assemblies used for weapon guidance or sniper rifle scopes has attracted interest for security and military applications. Typically a laser system is used to interrogate a scene of interest and the retro-reflected radiation is detected. Different system approaches for area coverage can be realised ranging from flood illumination to step-and-stare or continuous scanning schemes. Independently of the chosen approach target discrimination is a crucial issue, particularly if a complex scene such as in an urban environment and autonomous operation is considered. In this work target discrimination strategies in optics detection are discussed. Typical parameters affecting the reflected laser radiation from the target are the wavelength, polarisation properties, temporal effects and the range resolution. Knowledge about the target characteristics is important to predict the target discrimination capability. Two different systems were used to investigate polarisation properties and range resolution information from targets including e.g. road signs, optical reflexes, rifle sights and optical references. The experimental results and implications on target discrimination will be discussed. If autonomous operation is required target discrimination becomes critical in order to reduce the number of false alarms.

  11. Physical sciences research plans for the International Space Station.

    PubMed

    Trinh, E H

    2003-01-01

    The restructuring of the research capabilities of the International Space Station has forced a reassessment of the Physical Sciences research plans and a re-targeting of the major scientific thrusts. The combination of already selected peer-reviewed flight investigations with the initiation of new research and technology programs will allow the maximization of the ISS scientific and technological potential. Fundamental and applied research will use a combination of ISS-based facilities, ground-based activities, and other experimental platforms to address issues impacting fundamental knowledge, industrial and medical applications on Earth, and the technology required for human space exploration. The current flight investigation research plan shows a large number of principal investigators selected to use the remaining planned research facilities. c2003 American Institute of Aeronautics and Astronautics. Published by Elsevier Science Ltd. All rights reserved.

  12. Physical sciences research plans for the International Space Station

    NASA Technical Reports Server (NTRS)

    Trinh, E. H.

    2003-01-01

    The restructuring of the research capabilities of the International Space Station has forced a reassessment of the Physical Sciences research plans and a re-targeting of the major scientific thrusts. The combination of already selected peer-reviewed flight investigations with the initiation of new research and technology programs will allow the maximization of the ISS scientific and technological potential. Fundamental and applied research will use a combination of ISS-based facilities, ground-based activities, and other experimental platforms to address issues impacting fundamental knowledge, industrial and medical applications on Earth, and the technology required for human space exploration. The current flight investigation research plan shows a large number of principal investigators selected to use the remaining planned research facilities. c2003 American Institute of Aeronautics and Astronautics. Published by Elsevier Science Ltd. All rights reserved.

  13. Effect of online pedometer program on physical activity in Qatar.

    PubMed

    Al-Kuwari, Mohamed G; Al-Mohannadi, Abdulla S; El-Jack, Izzeldin I; Almudahka, Fuad

    2016-03-01

    The aim of this study is to assess the effectiveness of pedometers as motivation for individuals to walk 10,000 steps and more a day. A cross-sectional longitudinal study conducted during for 12 weeks. The intervention consists of goal setting to reach 10,000 steps or more and to keep it as daily target. The pedometer was issued for every participant after they were registered at the website and given a self-monitoring on line account. Participants were informed to upload their data every week. An automated e-mail and text messages were sent to participant didn't upload the data. Average daily steps measured in the 1st week were taken as baseline, and the average weekly steps were measured at the 4, 8, and 12 weeks. The study included 970 adults, and showed a significant increase in average daily steps from 6.833±4.144 steps/day at baseline into 10.600±6,385 steps/week at the 12th week (P<0.001), 19.3% met the daily target of 10,000 steps or more at the baseline with considerable increase to 45.0% by the 12th week. However this increase is more obvious in females as only 11.7% of them met the daily target of 10,000 steps at start and reached to 38.5% at the 12th week. At the 12th week the age group ≥45 years became more active with pedometer than the younger age group (48.5% vs. 43.2%). Although adults from different races showed increasing physical activity however Arabs remain less active than other ethnic groups (39.0% and 53.3% respectively). Pedometer program was found to be effective in promoting physical activity in Qatar. Daily steps goal is encouraging adults for achieving their recommended daily physical activity level. This intervention is more useful for adults and women in particular.

  14. Understanding and Developing Controversial Issues in College Courses.

    ERIC Educational Resources Information Center

    Payne, Brian K.; Gainey, Randy R.

    2003-01-01

    Discusses common controversial issues in different college disciplines, such as the death penalty and drug legalization. Also suggests useful methods for encouraging enlightening discussions, such as verbal and physical cues, student-centered activities, and text selection. (SLD)

  15. Genetic Testing for Rare Cancer: The Wider Issues.

    PubMed

    Jacobs, Chris; Pichert, Gabriella

    2016-01-01

    Identification of a potential genetic susceptibility to cancer and confirmation of a pathogenic gene mutation raises a number of challenging issues for the patient with cancer, their relatives and the health professionals caring for them. The specific risks and management issues associated with rare cancer types have been addressed in the earlier chapters. This chapter considers the wider issues involved in genetic counselling and genetic testing for a genetic susceptibility to cancer for patients, families and health professionals. The first part of the chapter will present the issues raised by the current practice in genetic counselling and genetic testing for cancer susceptibility. The second part of the chapter will address some of the issues raised by the advances in genetic testing technology and the future opportunities provided by personalised medicine and targeted cancer therapy. Facilitating these developments requires closer integration of genomics into mainstream cancer care, challenging the existing paradigm of genetic medicine, adding additional layers of complexity to the risk assessment and management of cancer and presenting wider issues for patients, families, health professionals and clinical services.

  16. Beyond quantum probability: another formalism shared by quantum physics and psychology.

    PubMed

    Dzhafarov, Ehtibar N; Kujala, Janne V

    2013-06-01

    There is another meeting place for quantum physics and psychology, both within and outside of cognitive modeling. In physics it is known as the issue of classical (probabilistic) determinism, and in psychology it is known as the issue of selective influences. The formalisms independently developed in the two areas for dealing with these issues turn out to be identical, opening ways for mutually beneficial interactions.

  17. [Medical-legal issues of physical and pharmacological restraint].

    PubMed

    Gómez-Durán, Esperanza L; Guija, Julio A; Ortega-Monasterio, Leopoldo

    2014-03-01

    The use of physical and pharmacological restraint is controversial but is currently accepted as inevitable. It is indicated for controlling behavioral disorders and psychomotor agitation that put patients and third parties at risk. Its indication should be medical, and we should opt for the least restrictive measure. Restraints represent a possible infringement of patients' fundamental rights and require understanding and strict respect for the medical-legal precepts by physicians and other practitioners involved in its application. This article reviews the current legal framework, as well as the medical-legal premises and aspects of applying restraints, with the objective of ensuring maximum respect for patients' rights and the appropriate legal safety in the activity of practitioners. Copyright © 2014 Elsevier España, S.L. All rights reserved.

  18. Physical activity in patients with type 2 diabetes and hypertension--insights into motivations and barriers from the MOBILE study.

    PubMed

    Duclos, Martine; Dejager, Sylvie; Postel-Vinay, Nicolas; di Nicola, Sylvie; Quéré, Stéphane; Fiquet, Béatrice

    2015-01-01

    Although physical activity (PA) is key in the management of type 2 diabetes (T2DM) and hypertension, it is difficult to implement in practice. Cross-sectional, observational study. Participating physicians were asked to recruit two active and four inactive patients, screened with the Ricci-Gagnon (RG) self-questionnaire (active if score ≥16). Patients subsequently completed the International Physical Activity Questionnaire. The objective was to assess the achievement of individualized glycated hemoglobin and blood pressure goals (<140/90 mmHg) in the active vs inactive cohort, to explore the correlates for meeting both targets by multivariate analysis, and to examine the barriers and motivations to engage in PA. About 1,766 patients were analyzed. Active (n=628) vs. inactive (n=1,138) patients were more often male, younger, less obese, had shorter durations of diabetes, fewer complications and other health issues, such as osteoarticular disorders (P<0.001 for all). Their diabetes and hypertension control was better and obtained despite a lower treatment burden. The biggest difference in PA between the active vs inactive patients was the percentage who declared engaging in regular leisure-type PA (97.9% vs. 9.6%), also reflected in the percentage with vigorous activities in International Physical Activity Questionnaire (59.5% vs. 9.6%). Target control was achieved by 33% of active and 19% of inactive patients (P<0.001). Active patients, those with fewer barriers to PA, with lower treatment burden, and with an active physician, were more likely to reach targets. The physician's role emerged in the motivations (reassurance on health issues, training on hypoglycemia risk, and prescription/monitoring of the PA by the physician). A negative self-image was the highest ranked barrier for the inactive patients, followed by lack of support and medical concerns. Physicians should consider PA prescription as seriously as any drug prescription, and take into account

  19. MO-FG-BRB-00: AAPM Presidential Debate [medical physics education

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    Building on the energy and excitement of Washington DC in a presidential election year, AAPM will host its own Presidential Debate to better understand the views of the AAPM membership! Past presidents of the AAPM, Drs. Bayouth, Hazle, Herman, and Seibert, will debate hot topics in medical physics including issues facing education, professional practice, and the advancement of science. The moderators, Drs. Brock and Stern, will also draw in topics from Point-Counterpoint articles from the Medical Physics Journals. Wrapping up the debate, the audience will have the opportunity to question the candidates in a town hall format. At the conclusionmore » of this lively debate, the winner will be decided by the audience, so bring your Audience Response Units! Be part of Medical Physics - Decision 2016! Learning Objectives: Understand AAPM members’ views and opinions on issues facing medical physics education Learn AAPM members’ views and opinions on issues facing professional practice Identify AAPM members’ view and opinions on issues facing the advancement of science in medical physics J. Bayouth, Funding support from NCI;Scientific Advisory Board member - ViewRay.« less

  20. Application of nuclear physics in medical physics and nuclear medicine

    NASA Astrophysics Data System (ADS)

    Hoehr, Cornelia

    2016-09-01

    Nuclear physics has a long history of influencing and advancing medical fields. At TRIUMF we use the applications of nuclear physics to diagnose several diseases via medical isotopes and treat cancer by using proton beams. The Life Science division has a long history of producing Positron Emission Tomography (PET) isotopes but we are also investigating the production of SPECT and PET isotopes with a potential shortage for clinical operation or otherwise limited access to chemists, biologists and medical researchers. New targets are being developed, aided by a simulation platform investigating the processes inside a target under proton irradiation - nuclear, thermodynamic, and chemical. Simulations also aid in the development of new beam-shaping devices for TRIUMF's Proton Therapy facility, Canada's only proton therapy facility, as well as new treatment testing systems. Both promise improved treatment delivery for cancer patients.

  1. Impact of target-to-background ratio, target size, emission scan duration, and activity on physical figures of merit for a 3D LSO-based whole body PET/CT scanner.

    PubMed

    Brambilla, M; Matheoud, R; Secco, C; Sacchetti, G; Comi, S; Rudoni, M; Carriero, A; Inglese, E

    2007-10-01

    The aim of our work is to describe the way in which physical figures of merit such as contrast-to-noise ratio (CNR) behave when varying acquisition parameters such as emission scan duration (ESD) or activity at the start of acquisition (A(acq)) that in clinical practice can be selected by the user, or object properties such as target dimensions or target-to-background (T/B) ratio, which depend uniquely on the intrinsic characteristics of the object being imaged. Figures of merit, used to characterize image quality and quantitative accuracy for a 3D-LSO based PET/CT scanner, were studied as a function of ESD and A(acq) for different target sizes and T/B ratios using a multivariate approach in a wide range of conditions approaching the ones that can be encountered in clinical practice. An annular ring of water bags of 3 cm thickness was fitted over an IEC phantom in order to obtain counting rates similar to those found in average patients. The average scatter fraction (SF) of the modified IEC phantom was similar to the mean SF measured on patients with a similar scanner. A supplemental set of micro-hollow spheres was positioned inside the phantom. The NEMA NU 2-2001 scatter phantom was positioned at the end of the IEC phantom to approximate the clinical situation of having activity that extends beyond the scanner. The phantoms were filled with a solution of water and 18F (12 kBq/mL) and the spheres with various T/B ratios of 22.5, 10.3, and 3.6. Sequential imaging was performed to acquire PET images with varying background activity concentrations of about 12, 9, 6.4, 5.3, and 3.1 kBq/mL, positioned on the linear portion of the phantom's NECR curve, well below peak NECR of 61.2 kcps that is reached at 31.8 kBq/mL. The ESD was set to 1, 2, 3, and 4 min/bed. With T/B ratios of 3.6, 10.3, and 22.5, the 13.0, 8.1, and 6.5 mm spheres were detectable for the whole ranges of background activity concentration and ESD, respectively. The ESD resulted as the most significant

  2. Ethical Issues in Sports Medicine

    PubMed Central

    Greenfield, Bruce H.; West, Charles Robert

    2012-01-01

    Ethical issues present a challenge for health care professionals working with athletes of sports teams. Health care professionals—including the team physician, the physical therapist, and the athletic trainer—are faced with the challenge of returning an athlete to competition as quickly as possible but as safely as possible. Conflicts of interest arise due to conflicting obligations of the team physician to the athlete and other members of the sports organization, including coaches and the team owner. The multiple stakeholders involved in sports teams challenge the traditional notion of confidentiality and autonomy. The aims of this article are to explicate the ethics of sports medicine, highlight the ethical issues, and provide some strategies and suggestions for ethical decision making. PMID:24179585

  3. SmallSat Missions Traveling to Planetary Targets from Near-Earth-Space: Applications for Space Physics

    NASA Astrophysics Data System (ADS)

    Espley, J. R.; Folta, D.

    2017-12-01

    Recent advances in propulsion technology and interplanetary navigation theoretically allow very small spacecraft to travel directly to planetary destinations from near-Earth-space. Because there are currently many launches with excess mass capability (NASA, military, and even commercial), we anticipate a dramatic increase in the number of opportunities for missions to planetary targets. Spacecraft as small as 12U CubeSats can use solar electric propulsion to travel from Earth-orbit to Mars-orbit in approximately 2-3 years. Space physics missions are particularly well suited for such mission architectures since state-of-the-art instrumentation to answer fundamental science questions can be accommodated in relatively small payload packages. For example, multi-point measurements of the martian magnetosphere, ionosphere, and crustal magnetic fields would yield important new science results regarding atmospheric escape and the geophysical history of the martian surface. These measurements could be accomplished by a pair of 12U CubeSats with world-class instruments that require only modest mass, power, and telemetry resources (e.g. Goddard's mini-fluxgate vector magnetometer).

  4. The target vacuum storage facility at iThemba LABS

    NASA Astrophysics Data System (ADS)

    Neveling, R.; Kheswa, N. Y.; Papka, P.

    2018-05-01

    A number of nuclear physics experiments at iThemba LABS require target foils that consist of specific isotopes of elements which are reactive in air. Not only is it important to prepare these targets in a suitable environment to prevent oxidation, but consideration should also be given to the long term storage and handling facilities of such targets. The target vacuum storage facility at iThemba LABS, as well as additional hardware necessary to transport and install the target foils in the experimental chamber, will be discussed.

  5. Beauty and charm production at fixed-target experiments

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Erik E. Gottschalk

    Fixed-target experiments continue to provide insights into the physics of particle production in strong interactions. The experiments are performed with different types of beam particles of varying energies, and many different target materials. Studies of beauty and charm production are of particular interest, since experimental results can be compared to perturbative QCD calculations. It is in this context that recent results from fixed-target experiments on beauty and charm production will be reviewed.

  6. Lack of genitourinary physical examination before urologic consultation--a quality of care issue.

    PubMed

    Ylitalo, Adam W; Ylitalo, Kelly R; Santucci, Richard A

    2012-12-01

    To quantify the frequency of genitourinary (GU) physical examinations obtained by the emergency department or primary hospital team before obtaining a urologic consultation and evaluate the role of the different demographic and clinical factors. For 6 weeks, from July to August 2010, 420 consecutive patients evaluated by the urology consultation service had their medical charts reviewed retrospectively, with the frequency of GU physical examination performed by the emergency department or primary hospital team recorded. Of 357 patients requiring a urologic consultation, 88 of 324 (27%) had a GU physical examination performed by the emergency department and 98 of 319 (31%) had a GU physical examination performed by the primary hospital team before the urologic consultation. The emergency department was 6 times more likely to perform a GU physical examination on a male patient than a female patient, and the primary team was twice as likely to perform a GU physical examination on a male patient than a female patient. The likelihood of examination by either team decreased as patients became older. Race was not significantly associated with the likelihood of examination. The results of our study indicate that examinations are performed less than one-third of the time before obtaining a urologic consultation, with the frequency related to age and sex. The low rate of preconsultation examination creates concern for quality of care, the correctness of billing, and unnecessary urologic consultations. Copyright © 2012 Elsevier Inc. All rights reserved.

  7. Investigation of the effect of physical parameters on the design of tumour targeting agents

    NASA Astrophysics Data System (ADS)

    Casey, Joanne Lois

    Tumour targeting using radiolabelled antibodies for radioimmunodetection (RAID) and radioimmunotherapy (RIT) has been studied for many years. The main factors that have limited clinical success are low tumour uptake, immunogenicity and poor therapeutic ratios. This thesis has applied current technology to make advances in this area of research. The effect of physical parameters (antibody size, valency, affinity and charge) on the design of tumour targeting agents was studied by constructing divalent (DFM) and trivalent (TFM) forms of the murine anti-CEA antibody A5B7 Fab' by chemical cross-linking. This involves partial reduction of the hinge disulphides to expose thiol (-SH) groups and subsequent reaction with a maleimide cross-linker to form a thioether bond at the hinge region. Previous studies have suggested that the stability of thioether bonds is superior to naturally occurring disulphide bonds present at the hinge region of IgG and F(ab')2. The aim was to compare the functional affinities and in vivo tumour targeting in nude mice bearing human tumour xenografts of DFM and TFM to similar sized parent IgG and F(ab')2. Radiolabelling with 131I and 90Y was also compared with a view to determine which combination would be optimal for RIT. Results clearly demonstrated a significantly faster on-rate of DFM compared to all other antibody forms and estimated dosimetry analysis suggested that DFM would be the most suitable antibody form radiolabelled with 131I for RIT. Both F(ab')2 and DFM showed high kidney uptake levels on labelling with which is unacceptable for RIT. Despite the improved tumour: blood ratios for TFM, the increased estimated dose to normal tissues and lower therapeutic effect in RIT studies suggests that the most promising combination with the radionuclide appears to be IgG. A humanised version of A5B7 hFab' has been constructed previously in order to reduce its immunogenicity in man. The in vivo stability of hDFM proved to be superior to hF(ab')2

  8. Science and technology review, July-August 1998 issue

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smart, J

    On the occasion of Edward Teller's 90th birthday, S&TR has the pleasure of honoring Lawrence Livermore's co-founder and most influential scientist. Teller is known for his inventive work in physics, his concepts leading to thermonuclear explosions, and his strong stands on such issues as science education, the nation's strategic defense, the needs for science in the future, and sharing scientific information. The articles in this issue also show him, as always, tirelessly moving forward with his new and changing interests.

  9. Cyber / Physical Security Vulnerability Assessment Integration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    MacDonald, Douglas G.; Simpkins, Bret E.

    Abstract Both physical protection and cyber security domains offer solutions for the discovery of vulnerabilities through the use of various assessment processes and software tools. Each vulnerability assessment (VA) methodology provides the ability to identify and categorize vulnerabilities, and quantifies the risks within their own areas of expertise. Neither approach fully represents the true potential security risk to a site and/or a facility, nor comprehensively assesses the overall security posture. The technical approach to solving this problem was to identify methodologies and processes that blend the physical and cyber security assessments, and develop tools to accurately quantify the unaccounted formore » risk. SMEs from both the physical and the cyber security domains developed the blending methodologies, and cross trained each other on the various aspects of the physical and cyber security assessment processes. A local critical infrastructure entity volunteered to host a proof of concept physical/cyber security assessment, and the lessons learned have been leveraged by this effort. The four potential modes of attack an adversary can use in approaching a target are; Physical Only Attack, Cyber Only Attack, Physical Enabled Cyber Attack, and the Cyber Enabled Physical Attack. The Physical Only and the Cyber Only pathway analysis are two of the most widely analyzed attack modes. The pathway from an off-site location to the desired target location is dissected to ensure adversarial activity can be detected and neutralized by the protection strategy, prior to completion of a predefined task. This methodology typically explores a one way attack from the public space (or common area) inward towards the target. The Physical Enabled Cyber Attack and the Cyber Enabled Physical Attack are much more intricate. Both scenarios involve beginning in one domain to affect change in the other, then backing outward to take advantage of the reduced system effectiveness

  10. Drug target inference through pathway analysis of genomics data

    PubMed Central

    Ma, Haisu; Zhao, Hongyu

    2013-01-01

    Statistical modeling coupled with bioinformatics is commonly used for drug discovery. Although there exist many approaches for single target based drug design and target inference, recent years have seen a paradigm shift to system-level pharmacological research. Pathway analysis of genomics data represents one promising direction for computational inference of drug targets. This article aims at providing a comprehensive review on the evolving issues is this field, covering methodological developments, their pros and cons, as well as future research directions. PMID:23369829

  11. Journal Literature Covered by Physics Abstracts in 1965.

    ERIC Educational Resources Information Center

    Keenan, Stella; Brickwedde, F.G.

    A study of the publications of the Physics Journal literature has been made, utilizing the 1965 issues of Physics Abstracts. It is intended to provide a profile of the physics literature and statistical information on physics abstract coverage. It deals with abstracts from serial (journal) publications and includes some 32,000 articles from 495…

  12. 1989 Environmental Issues and Priorities Survey, Executive Summary.

    ERIC Educational Resources Information Center

    HRN Co., Philadelphia, PA.

    This survey was designed to target approximately 7,000 leaders in business, education, media, environmental advocacy, and government in ten regional areas throughout the United States. The survey was designed to accomplish the following: identify the environmental priorities, determine leaders' perceptions on a range of policy-related issues, and…

  13. Examining the Role of Mental Health and Clinical Issues within Talent Development

    PubMed Central

    Hill, Andy; MacNamara, Áine; Collins, Dave; Rodgers, Sheelagh

    2016-01-01

    Although significant research supports the association between physical activity and mental wellbeing, current literature acknowledges that athletes are no less susceptible to mental illness than the general population. Despite welcomed initiatives aimed at improving mental health within elite sport, these programs often fail to target young athletes; an important concern given that the genesis of many mental illnesses are recognized to occur during this critical period. Given the importance of early intervention and effective treatment, and the potentially devastating consequences of clinical issues going undiagnosed, the implications for talent identification and development (TID) become obvious. With this in mind, this study sought to examine the range of mental health issues that may impact upon developing athletes and potential consequences for the development process, specific risk and protective factors associated with talent development, along with an examination of current practices concerning the identification of mental health issues in such environments. Qualitative interviews were conducted with purposively sampled clinicians (n = 8) experienced in working with adolescents and/or young athletes. Inductive content analysis was undertaken, identifying four main themes: key behavioral indicators; associated risk factors; associated protective factors; and issues around identification and diagnosis. Key behavioral indicators included behavioral change, along with behaviors associated with eating disorders, anxiety and depression. Risk factors centered on family background, the performance environment, and issues surrounding adolescence. Protective factors were primarily social in nature. Finally, a lack of awareness and understanding of clinical issues, multiple causes of symptoms, non-disclosure and the need for triangulation of assessment were identified. The need for improved identification and intervention strategies was apparent, with coaches

  14. Examining the Role of Mental Health and Clinical Issues within Talent Development.

    PubMed

    Hill, Andy; MacNamara, Áine; Collins, Dave; Rodgers, Sheelagh

    2015-01-01

    Although significant research supports the association between physical activity and mental wellbeing, current literature acknowledges that athletes are no less susceptible to mental illness than the general population. Despite welcomed initiatives aimed at improving mental health within elite sport, these programs often fail to target young athletes; an important concern given that the genesis of many mental illnesses are recognized to occur during this critical period. Given the importance of early intervention and effective treatment, and the potentially devastating consequences of clinical issues going undiagnosed, the implications for talent identification and development (TID) become obvious. With this in mind, this study sought to examine the range of mental health issues that may impact upon developing athletes and potential consequences for the development process, specific risk and protective factors associated with talent development, along with an examination of current practices concerning the identification of mental health issues in such environments. Qualitative interviews were conducted with purposively sampled clinicians (n = 8) experienced in working with adolescents and/or young athletes. Inductive content analysis was undertaken, identifying four main themes: key behavioral indicators; associated risk factors; associated protective factors; and issues around identification and diagnosis. Key behavioral indicators included behavioral change, along with behaviors associated with eating disorders, anxiety and depression. Risk factors centered on family background, the performance environment, and issues surrounding adolescence. Protective factors were primarily social in nature. Finally, a lack of awareness and understanding of clinical issues, multiple causes of symptoms, non-disclosure and the need for triangulation of assessment were identified. The need for improved identification and intervention strategies was apparent, with coaches

  15. A systematic review of school-based eHealth interventions targeting alcohol use, smoking, physical inactivity, diet, sedentary behaviour and sleep among adolescents: a review protocol.

    PubMed

    Champion, Katrina E; Newton, Nicola C; Spring, Bonnie; Wafford, Q Eileen; Parmenter, Belinda J; Teesson, Maree

    2017-12-06

    Six key behavioural risk factors (risky alcohol use, smoking, poor diet, physical inactivity, sedentary behaviour and unhealthy sleep patterns) have been identified as strong determinants of chronic disease, such as cardiovascular disease, diabetes and cancers. School-based interventions targeting these multiple health risk behaviours among adolescents have the potential to halt the trajectory towards later disease, whilst online and mobile technology interventions offer advantages in terms of student engagement, reach and scalability. Despite this, the efficacy of eHealth school-based interventions targeting these six health risk behaviours among adolescents has not been evaluated. The proposed systematic review aims to address this by determining the nature and efficacy of existing eHealth school-based interventions targeting multiple health risk behaviours among adolescents. A systematic search of the MEDLINE, Embase, PsycINFO and Cochrane Library databases will be conducted to identify eligible published papers. Eligible studies will be randomised controlled trials, including cluster randomised controlled trials, of interventions targeting two or more of the following lifestyle risk behaviours: alcohol use, smoking, poor diet, physical inactivity, sedentary behaviour and sleep. Eligible studies will be those evaluating interventions delivered in a secondary school setting among participants 11-18 years of age, via an eHealth platform (Internet, computers of mobile technology). Two reviewers will independently screen studies for eligibility, extract data and assess the risk of bias. Study outcomes will be summarised in a narrative synthesis, and meta-analyses will be conducted where it is appropriate to combine studies. It is anticipated that the results from this review will serve to inform the development of future eHealth multiple health behaviour interventions for adolescents by identifying common characteristics of effective programs and highlighting

  16. Using link analysis to explore the impact of the physical environment on pharmacist tasks.

    PubMed

    Lester, Corey A; Chui, Michelle A

    2016-01-01

    National community pharmacy organizations have been redesigning pharmacies to better facilitate direct patient care. However, evidence suggests that changing the physical layout of a pharmacy prior to understanding how the environment impacts pharmacists' work may not achieve the desired benefits. This study describes an objective method to understanding how the physical layout of the pharmacy may affect how pharmacists perform tasks. Link analysis is a systems engineering method used to describe the influence of the physical environment on task completion. This study used a secondary data set of field notes collected from 9 h of direct observation in one mass-merchandise community pharmacy in the U.S. State, Wisconsin. A node is an individual location in the environment. A link is the movement between two nodes. Tasks were inventoried and task themes identified. The mean, minimum, and maximum number of links needed to complete each task were then determined and used to construct a link table. A link diagram is a graphical display showing the links in conjunction with the physical layout of the pharmacy. A total of 92 unique tasks were identified resulting in 221 links. Tasks were sorted into five themes: patient care activities, insurance issues, verifying prescriptions, filling prescriptions, and other. Insurance issues required the greatest number of links with a mean of 4.75. Verifying prescriptions and performing patient care were the most commonly performed tasks with 36 and 30 unique task occurrences, respectively. Link analysis provides an objective method for identifying how a pharmacist interacts with the physical environment to complete tasks. This method provides designers with useful information to target interventions to improve the effectiveness of pharmacist work. Analysis beyond link analysis should be considered for large scale system redesign. Copyright © 2015 Elsevier Inc. All rights reserved.

  17. Towards Integrating Soil Quality Monitoring Targets as Measures of Soil Natural Capital Stocks with the Provision of Ecosystem Services

    NASA Astrophysics Data System (ADS)

    Taylor, M. D.; Mackay, A. D.; Dominati, E.; Hill, R. B.

    2012-04-01

    This paper presents the process used to review soil quality monitoring in New Zealand to better align indicators and indicator target ranges with critical values of change in soil function. Since its inception in New Zealand 15 year ago, soil quality monitoring has become an important state of the environment reporting tool for Regional Councils. This tool assists councils to track the condition of soils resources, assess the impact of different land management practices, and provide timely warning of emerging issues to allow early intervention and avoid irreversible loss of natural capital stocks. Critical to the effectiveness of soil quality monitoring is setting relevant, validated thresholds or target ranges. Provisional Target Ranges were set in 2003 using expert knowledge available and data on production responses. Little information was available at that time for setting targets for soil natural capital stocks other than those for food production. The intention was to revise these provisional ranges as further information became available and extend target ranges to cover the regulating and cultural services provided by soils. A recently developed ecosystems service framework was used to explore the feasibility of linking soil natural capital stocks measured by the current suite of soil quality indicators to the provision of ecosystem services by soils. Importantly the new approach builds on and utilises the time series data sets collected by current suite of soil quality indicators, adding value to the current effort, and has the potential to set targets ranges based on the economic and environmental outcomes required for a given farm, catchment or region. It is now timely to develop a further group of environmental indicators for measuring specific soil issues. As with the soil quality indicators, these environmental indicators would be aligned with the provision of ecosystem services. The toolbox envisaged is a set of indicators for specific soil issues

  18. Development of a Secondary School Physics Program: Harvard Project Physics. Volume 2, More Appendices. Final Report.

    ERIC Educational Resources Information Center

    Holton, Gerald; And Others

    As appendices to the final report on Project Physics (SE 015 500), this volume includes parts of the original documents concerning the project development. Articles published in the "Physics Teacher" are included in reprint form. Evaluation and research papers along with related materials issued in other publications are grouped into…

  19. Block Ignition Inertial Confinement Fusion (ICF) with Condensed Matter Cluster Type Targets for p-B11 Powered Space Propulsion

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miley, George H.; Hora, H.; Badziak, J.

    The use of laser-driven Inertial Confinement Fusion (ICF) for space propulsion has been the subject of several earlier conceptual design studies, (see: Orth, 1998; and other references therein). However, these studies were based on older ICF technology using either 'direct' or 'in-direct x-ray driven' type target irradiation. Important new directions have opened for laser ICF in recent years following the development of 'chirped' lasers capable of ultra short pulses with powers of TW up to few PW which leads to the concept of 'fast ignition (FI)' to achieve higher energy gains from target implosions. In a recent publication the authorsmore » showed that use of a modified type of FI, termed 'block ignition' (Miley et al., 2008), could meet many of the requirements anticipated (but not then available) by the designs of the Vehicle for Interplanetary Space Transport Applications (VISTA) ICF fusion propulsion ship (Orth, 2008) for deep space missions. Subsequently the first author devised and presented concepts for imbedding high density condensed matter 'clusters' of deuterium into the target to obtain ultra high local fusion reaction rates (Miley, 2008). Such rates are possible due to the high density of the clusters (over an order of magnitude above cryogenic deuterium). Once compressed by the implosion, the yet higher density gives an ultra high reaction rate over the cluster volume since the fusion rate is proportional to the square of the fuel density. Most recently, a new discovery discussed here indicates that the target matrix could be composed of B{sup 11} with proton clusters imbedded. This then makes p-B{sup 11} fusion practical, assuming all of the physics issues such as stability of the clusters during compression are resolved. Indeed, p-B{sup 11} power is ideal for fusion propulsion since it has a minimum of unwanted side products while giving most of the reaction energy to energetic alpha particles which can be directed into an exhaust (propulsion

  20. Physics Insight into "The Canterbury Tales" Chronotope

    ERIC Educational Resources Information Center

    Bogdanov, S. R.; Oversby, J.; Popov, O. A.; Teteleva, E. M.

    2015-01-01

    Many students regard physics as an isolated, sophisticated and perhaps a boring branch of science. Meanwhile, physics is embedded in most events and issues of society, culture and everyday life. To find and include such relevant contexts is one of the challenges for every physics teacher. Here we present our findings, which concern the classic…

  1. Dynamical and Physical Properties of 65803 Didymos, the Proposed AIDA Mission Target

    NASA Astrophysics Data System (ADS)

    Richardson, Derek C.; Barnouin, Olivier S.; Benner, Lance A. M.; Bottke, William; Campo Bagatin, Adriano; Cheng, Andrew F.; Eggl, Siegfried; Hamilton, Douglas P.; Hestroffer, Daniel; Hirabayashi, Masatoshi; Maurel, Clara; McMahon, Jay W.; Michel, Patrick; Murdoch, Naomi; Naidu, Shantanu P.; Pravec, Petr; Rivkin, Andrew S.; Rosenblatt, Pascal; Sarid, Gal; Scheeres, Daniel J.; Scheirich, Peter; Tsiganis, Kleomenis; Zhang, Yun; AIDA Dynamical and Physical Properties of Didymos Working Group

    2016-10-01

    Binary near-Earth asteroid (NEA) 65803 Didymos is the proposed Asteroid Impact & Deflection Assessment (AIDA) mission target, combining an orbiter [1] and a kinetic impactor for a planned encounter in fall 2022 [2]. The Dynamical and Physical Properties of Didymos Working Group supports this mission by addressing questions related to understanding the dynamical state of the system and inferring physical properties. Didymos is an Apollo-class NEA that likely reached its current orbit by exiting the inner main belt near or within the nu-6 resonance (> 82% chance) [3]. Remote observations [4] show Didymos is spectroscopically most consistent with ordinary chondrites. The diameters of the binary components are measured to be about 780 and 160 m [5]. A model of the short-term binary dynamics suggests possible librations of the secondary with up to ~10-deg amplitude, depending on its axial ratio. However, an equilibrium orbital and rotational solution is consistent with a libration amplitude of only ~1 deg. The primary, with an estimated 2.1 g/cc bulk density (uncertainty 30%) has a possibly super-critical rotation period of 2.26 h that may imply a cohesive strength of several tens of Pa. At this rate, perturbed regolith material may go through take-off/landing cycles and cause loss of fines due to solar radiation pressure. Based on a continuum analysis [6], the internal structure would likely fail before the equatorial region. A discrete analysis [7,8] shows that a minimum of 2.5 g/cc bulk density is needed for the structure to hold without cohesion. The system may be subject to weak thermal radiation forces (BYORP) with a period drift of no greater than 1 s/yr [9]. Experiments using the ISAE-SUPAERO drop tower [10] are underway to model the possible deployment of a lander on the secondary. References: [1] Michel et al. 2016, ASR 57, 2529; [2] Cheng et al. 2016, P&SS 127, 27; [3] Granvik et al. 2015, DPS 47, 214.07; [4] Dunn et al. 2013, LPSC 44, 1719; [5] Osip et al

  2. Healing with Books: Literature for Children Dealing with Health Issues.

    ERIC Educational Resources Information Center

    Cothern, Nancy

    1994-01-01

    Presents a 265-item annotated bibliography of literature for children dealing with health issues such as abuse, alcoholism, blindness, cancer, death, physical disabilities, and wheelchair dependency. (RS)

  3. High power neutron production targets

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wender, S.

    1996-06-01

    The author describes issues of concern in the design of targets and associated systems for high power neutron production facilities. The facilities include uses for neutron scattering, accelerator driven transmutation, accelerator production of tritium, short pulse spallation sources, and long pulse spallation sources. Each of these applications requires a source with different design needs and consequently different implementation in practise.

  4. Ca-48 targets - Home and abroad!

    NASA Astrophysics Data System (ADS)

    Greene, John P.; Carpenter, Michael; Janssens, Robert V. F.

    2018-05-01

    Using the method of reduction/distillation, high-purity films of robust and ductile calcium metal were prepared for use as targets in nuclear physics experiments. These targets, however, are extremely air-sensitive and procedures must be developed for their handling and use without exposure to the air. In most instances, the thin 48Ca target is used on a carrier foil (backing) and a thin covering film of similar material is employed to further reduce re-oxidation. Un-backed metallic targets are rarely produced due to these concerns. In addition, the low natural abundance of the isotope 48Ca provided an increased incentive for the best efficiencies available in their preparation. Here, we describe the preparation of 48Ca targets employing a gold backing and thin gold cover for use at home, Argonne National Laboratory (ANL), as well as abroad, at Osaka University. For the overseas shipments, much care and preparation were necessary to ensure good targets and safe arrival to the experimental facilities.

  5. Experimental study on ablative stabilization of Rayleigh-Taylor instability of laser-irradiated targets

    NASA Astrophysics Data System (ADS)

    Shigemori, Keisuke; Sakaiya, Tatsuhiko; Otani, Kazuto; Fujioka, Shinsuke; Nakai, Mitsuo; Azechi, Hiroshi; Shiraga, Hiroyuki; Tamari, Yohei; Okuno, Kazuki; Sunahara, Atsushi; Nagatomo, Hideo; Murakami, Masakatsu; Nishihara, Katsunobu; Izawa, Yasukazu

    2004-09-01

    Hydrodynamic instabilities are key issues of the physics of inertial confinement fusion (ICF) targets. Among the instabilities, Rayleigh-Taylor (RT) instability is the most important because it gives the largest growth factor in the ICF targets. Perturbations on the laser irradiated surface grow exponentially, but the growth rate is reduced by ablation flow. The growth rate γ is written as Takabe-Betti formula: γ = [kg/(1+kL)]1/2-βkm/pa, where k is wave number of the perturbation, g is acceleration, L is density scale-length, β is a coefficient, m is mass ablation rate per unit surface, and ρa is density at the ablation front. We experimentally measured all the parameters in the formula for polystyrene (CH) targets. Experiments were done on the HIPER laser facility at Institute of Laser Engineering, Osaka University. We found that the β value in the formula is ~ 1.7, which is in good agreements with the theoretical prediction, whereas the β for certain perturbation wavelengths are larger than the prediction. This disagreement between the experiment and the theory is mainly due to the deformation of the cutoff surface, which is created by non-uniform ablation flow from the ablation surface. We also found that high-Z doped plastic targets have multiablation structure, which can reduce the RT growth rate. When a low-Z target with high-Z dopant is irradiated by laser, radiation due to the high-Z dopant creates secondary ablation front deep inside the target. Since, the secondary ablation front is ablated by x-rays, the mass ablation rate is larger than the laser-irradiated ablation surface, that is, further reduction of the RT growth is expected. We measured the RT growth rate of Br-doped polystyrene targets. The experimental results indicate that of the CHBr targets show significantly small growth rate, which is very good news for the design of the ICF targets.

  6. Language, Literacy, and Educational Reform: Rethinking the Issues.

    ERIC Educational Resources Information Center

    Reyes, Maria de la Luz; McCollum, Pamela A.

    1992-01-01

    In spite of increasing ethnic, linguistic, and socioeconomic diversity, educational reform efforts continue to target mainstream English-speaking U.S. public. The educational plans of the America 2000 initiative are no exception. This theme issue provides examples of classroom-based research in which educators try to improve literacy education for…

  7. Health-Related Measures of Children's Physical Fitness.

    ERIC Educational Resources Information Center

    Pate, Russell R.

    1991-01-01

    Summarizes health-related physical fitness measurement procedures for children, emphasizing field measures. Health-related physical fitness encompasses cardiorespiratory endurance, body composition, muscular strength and endurance, and flexibility. The article presents several issues pertinent to research on health-related fitness testing. (SM)

  8. Promoting Physics Among Female Learners in the Western Cape Through Active Engagement (abstract)

    NASA Astrophysics Data System (ADS)

    Arendse, Gillian J.

    2009-04-01

    In 2006 the author organized a one-day intervention aimed at promoting physics among female learners at the University of Stellenbosch. The activities included an interactive lecture demonstration promoting active engagement, a hands-on session, and short presentations by female physicists addressing issues such as balancing family and career, breaking the stereotypes, and launching a successful career in physics. Each learner was expected to evaluate the program. In 2007 the author joined forces with Hip2B2 (Shuttleworth Foundation) to host a competition among grade-10 learners with the theme, ``promoting creativity through interactivity.'' The author was tasked by the Hip2B2-team to assist with a program for female learners planned for August 2008, coinciding with our national celebration of Women's Day. The event targeted 160 learners and took place in Durban, East London, Cape Town, and Johannesburg. The author shares some of the learners' experiences and personal triumphs.

  9. SAR target recognition using behaviour library of different shapes in different incidence angles and polarisations

    NASA Astrophysics Data System (ADS)

    Fallahpour, Mojtaba Behzad; Dehghani, Hamid; Jabbar Rashidi, Ali; Sheikhi, Abbas

    2018-05-01

    Target recognition is one of the most important issues in the interpretation of the synthetic aperture radar (SAR) images. Modelling, analysis, and recognition of the effects of influential parameters in the SAR can provide a better understanding of the SAR imaging systems, and therefore facilitates the interpretation of the produced images. Influential parameters in SAR images can be divided into five general categories of radar, radar platform, channel, imaging region, and processing section, each of which has different physical, structural, hardware, and software sub-parameters with clear roles in the finally formed images. In this paper, for the first time, a behaviour library that includes the effects of polarisation, incidence angle, and shape of targets, as radar and imaging region sub-parameters, in the SAR images are extracted. This library shows that the created pattern for each of cylindrical, conical, and cubic shapes is unique, and due to their unique properties these types of shapes can be recognised in the SAR images. This capability is applied to data acquired with the Canadian RADARSAT1 satellite.

  10. Trajectory of change in pain, depression, and physical functioning after physical activity adoption in fibromyalgia.

    PubMed

    Steiner, Jennifer L; Bigatti, Silvia M; Ang, Dennis C

    2015-07-01

    Fibromyalgia is associated with widespread pain, depression, and declines in physical functioning. The purpose of this study was to examine the trajectory of these symptoms over time related to physical activity adoption and maintenance via motivational interviewing versus education, to increase physical activity. There were no treatment group differences; we divided the sample (n = 184) based on changes in physical activity. Repeated measures analyses demonstrated differential patterns in depression, pain, and physical functioning at 24 and 36 weeks. Findings suggest increased physical activity may serve as a multiple-target intervention that provides moderate to large, long-lasting benefits for individuals with fibromyalgia. © The Author(s) 2013.

  11. Wellness at work. Boost wellness center participation with target marketing strategies.

    PubMed

    DeMoranville, C W; Schoenbachler, D D; Przytulski, J

    1998-01-01

    By using target marketing strategies, corporate wellness programs can increase employee participation rates and tailor activities to meet employee needs. The authors examined this issue through a research survey that segmented a university's staff and employee population into three wellness program groups: High Participators, Moderate Participators, and Low Participators. Participators' views on the following issues were analyzed: health management programs, exercise programs, wellness center use inhibitors, wellness center use incentives, wellness center communications, and willingness to pay for the wellness center. The results identified unique lifestyle characteristics for each group that can help make target marketing strategies effective.

  12. Interacting with target tracking algorithms in a gaze-enhanced motion video analysis system

    NASA Astrophysics Data System (ADS)

    Hild, Jutta; Krüger, Wolfgang; Heinze, Norbert; Peinsipp-Byma, Elisabeth; Beyerer, Jürgen

    2016-05-01

    Motion video analysis is a challenging task, particularly if real-time analysis is required. It is therefore an important issue how to provide suitable assistance for the human operator. Given that the use of customized video analysis systems is more and more established, one supporting measure is to provide system functions which perform subtasks of the analysis. Recent progress in the development of automated image exploitation algorithms allow, e.g., real-time moving target tracking. Another supporting measure is to provide a user interface which strives to reduce the perceptual, cognitive and motor load of the human operator for example by incorporating the operator's visual focus of attention. A gaze-enhanced user interface is able to help here. This work extends prior work on automated target recognition, segmentation, and tracking algorithms as well as about the benefits of a gaze-enhanced user interface for interaction with moving targets. We also propose a prototypical system design aiming to combine both the qualities of the human observer's perception and the automated algorithms in order to improve the overall performance of a real-time video analysis system. In this contribution, we address two novel issues analyzing gaze-based interaction with target tracking algorithms. The first issue extends the gaze-based triggering of a target tracking process, e.g., investigating how to best relaunch in the case of track loss. The second issue addresses the initialization of tracking algorithms without motion segmentation where the operator has to provide the system with the object's image region in order to start the tracking algorithm.

  13. Treatment of ankylosing spondylitis with biologics and targeted physical therapy: positive effect on chest pain, diminished chest mobility, and respiratory function.

    PubMed

    Gyurcsik, Z; Bodnár, N; Szekanecz, Z; Szántó, S

    2013-12-01

    Biologics are highly effective in ankylosing spondylitis (AS). In this self-controlled study, we assessed the additive value of complex physiotherapy in decreasing chest pain and tenderness and improving respiratory function in AS patients treated with tumor necrosis factor α (TNF-α) inhibitors. The trial consisted of 2 parts. In study I, clinical data of AS patients with (n=55) or without biological therapy (n=20) were retrospectively analyzed and compared. Anthropometrical data, duration since diagnosis and patient assessment of disease activity, pain intensity, tender points, sacroiliac joint involvement determined by X-ray, functional condition, and physical activity level were recorded. Subjective, functional, and physical tests were performed. In study II, 10 voluntary patients (6 men and 4 women, age 52.4 ± 13.6 years) with definite AS and receiving anti-TNF therapy were recruited. It was a prospective, non-randomized physiotherapeutic trial. BASFI (Bath Ankylosing Spondylitis Functional Index), BASDAI (Bath Ankylosing Spondylitis Disease Activity Index), modified Schober Index, occiput-to-wall distance, and fingertip-to-floor distance were evaluated. Forced vital capacity, forced 1-s expiratory volume, peak expiratory flow, and maximum voluntary ventilation were recorded. Furthermore, typical tender points were recorded. A targeted physiotherapy program was conducted twice a week for 12 weeks and all above parameters were recorded at baseline and after 12 weeks. Differences in patient assessment of disease activity (p=0.019) and pain intensity (p=0.017) were found in study I. Pain and tenderness of the thoracic spine were observed in both groups. Back pain without biologic therapy was slightly higher than other group. In study II, we found that patient assessment of disease activity and pain intensity significantly improved after the physical therapy program (p=0.002 and p<0.001). BASFI and BASDAI increased after treatment (p=0.004 and p<0.001). The

  14. Horizons of cybernetical physics

    PubMed Central

    2017-01-01

    The subject and main areas of a new research field—cybernetical physics—are discussed. A brief history of cybernetical physics is outlined. The main areas of activity in cybernetical physics are briefly surveyed, such as control of oscillatory and chaotic behaviour, control of resonance and synchronization, control in thermodynamics, control of distributed systems and networks, quantum control. This article is part of the themed issue ‘Horizons of cybernetical physics’. PMID:28115620

  15. Editorial: The role of medical physics in lung SBRT.

    PubMed

    Mancosu, Pietro; Nisbet, Andrew; Jornet, Núria

    2018-01-01

    Stereotactic body radiation therapy (SBRT) has become a standard treatment for non-operable patients with early stage non-small cell lung cancer (NSCLC). In this context, medical physics community has largely helped in the starting and the growth of this technique. In fact, SBRT requires the convergence of many different features for delivering large doses in few fractions to small moving target in an heterogeneous medium. The special issue of last month, was focused on the different physics challenges in lung SBRT. Eleven reviews were presented, covering: imaging for treatment planning and for treatment assessment; dosimetry and planning optimization; treatment delivery possibilities; image guidance during delivery; radiobiology. The current cutting edge role of medical physics was reported. We aimed to give a complete overview of different aspects of lung SBRT that would be of interest to both physicists implementing this technique in their institutions and more experienced physicists that would be inspired to start research projects in areas that still need further developments. We also feel that the role that medical physicists have played in the development and safe implementation of SBRT, particularly in lung region, can be taken as an excellent example to be translated to other areas, not only in Radiation Oncology but also in other health sectors. Copyright © 2018 Associazione Italiana di Fisica Medica. All rights reserved.

  16. School-Based Physical Activity Interventions: Effectiveness, Trends, Issues, Implications and Recommendations for Practice

    ERIC Educational Resources Information Center

    Cale, Lorraine; Harris, Jo

    2006-01-01

    The promotion of physical activity within schools and physical education (PE) has attracted growing interest in recent years. Schools have been acknowledged as the primary institution with responsibility for promoting activity in young people and more specifically, school PE has been recognized as having a key role to play. Given this, and based…

  17. A Fast MEANSHIFT Algorithm-Based Target Tracking System

    PubMed Central

    Sun, Jian

    2012-01-01

    Tracking moving targets in complex scenes using an active video camera is a challenging task. Tracking accuracy and efficiency are two key yet generally incompatible aspects of a Target Tracking System (TTS). A compromise scheme will be studied in this paper. A fast mean-shift-based Target Tracking scheme is designed and realized, which is robust to partial occlusion and changes in object appearance. The physical simulation shows that the image signal processing speed is >50 frame/s. PMID:22969397

  18. Relations of didactics of physics and projects of education in physics

    NASA Astrophysics Data System (ADS)

    Zelenický, Ľubomír; Rakovská, Mária

    2017-01-01

    Deepening interest in didactical problems of teaching physics can be from the beginning associated with the creation of the subject of physics, especially at secondary schools. In the 20th century it was no longer possible to ignore the rapid development of physical science and application of its results in practice. The subject of physics required the definition of its content, development of textbooks and, amongst others, new ways of teaching in comparison with the past. The interest of teachers focused mainly on increasing the clarity of explanation - the creation of experiments and teaching aids. Since 1926 Association of Mathematicians and Physicists in the first Czechoslovak Republic issued a didactic-methodological annex to the Journal of Mathematics and Physics, as a discussion in order to increase the quality of teaching. However, this action was spontaneous and subjective. In the second half of the 20th century didactics of physics became a study discipline, part of the training of future secondary school teachers and the development of scientific work in the field of Theory of teaching physics started.

  19. A Mathematics Entrance Exam for General (Non-Majors) Physics

    ERIC Educational Resources Information Center

    Chediak, Alex

    2010-01-01

    In a previous issue of "The Physics Teacher", John Hubisz explained how a mathematics background check has been used at three different colleges to determine the appropriate physics sequence for incoming students. Based on their performance, students are placed into either calculus-based physics (CBP), algebra-trig physics (ATP), or a year of…

  20. Generating Physics Content for the Designers.

    ERIC Educational Resources Information Center

    Bishop, Mary Jean; Bross, Thomas R.; Nelson, James H.

    2001-01-01

    Each designer contributing to this special issue was asked to prepare an introductory lesson on the physics of motion aimed at eighth to eleventh graders. This article presents a brief description of how a detailed physics content was researched, edited, and refined by subject-matter experts, and then ultimately presented to the instructional…

  1. [Genome-editing: focus on the off-target effects].

    PubMed

    He, Xiubin; Gu, Feng

    2017-10-25

    Breakthroughs of genome-editing in recent years have paved the way to develop new therapeutic strategies. These genome-editing tools mainly include Zinc-finger nucleases (ZFNs), Transcription activator-like effector nucleases (TALENs), and clustered regulatory interspaced short palindromic repeat (CRISPR)/Cas-based RNA-guided DNA endonucleases. However, off-target effects are still the major issue in genome editing, and limit the application in gene therapy. Here, we summarized the cause and compared different detection methods of off-targets.

  2. Outreach to Underrepresented Groups in Plasma Physics

    NASA Astrophysics Data System (ADS)

    Dominguez, A.; Zwicker, A.; Ortiz, D.; Greco, S. L.

    2017-10-01

    Physics, and specifically plasma physics, has a recruitment and retention problem for women and historically underrepresented minorities at all levels of their academic careers. For example, women make up approximately 8% of the APS-DPP membership while making up 13% of APS membership at large. In this presentation, we describe outreach activities we have undertaken targeting retention of these groups after their undergraduate careers. These include: Targeted recruitment visits for undergraduate research internships, as well as plasma physics workshops aimed at undergraduate women in physics, faculty members of minority serving institutions, and underrepresented undergraduates. After the first year of implementation, we have already seen results, including students reached through these programs participating in SULI undergraduate internships at PPPL. This work was support by a Grant from the DOE Office of Workforce Development for Teachers and Scientists (WDTS).

  3. Physical Activity | Cancer Trends Progress Report

    Cancer.gov

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  4. Observer's Interface for Solar System Target Specification

    NASA Astrophysics Data System (ADS)

    Roman, Anthony; Link, Miranda; Moriarty, Christopher; Stansberry, John A.

    2016-10-01

    When observing an asteroid or comet with HST, it has been necessary for the observer to manually enter the target's orbital elements into the Astronomer's Proposal Tool (APT). This allowed possible copy/paste transcription errors from the observer's source of orbital elements data. In order to address this issue, APT has now been improved with the capability to identify targets in and then download orbital elements from JPL Horizons. The observer will first use a target name resolver to choose the intended target from the Horizons database, and then download the orbital elements from Horizons directly into APT. A manual entry option is also still retained if the observer does not wish to use elements from Horizons. This new capability is available for HST observing, and it will also be supported for JWST observing. The poster shows examples of this new interface.

  5. Observer's Interface for Solar System Target Specification

    NASA Astrophysics Data System (ADS)

    Roman, Anthony; Link, Miranda; Moriarty, Christopher; Stansberry, John A.

    2016-01-01

    When observing an asteroid or comet with HST, it has been necessary for the observer to manually enter the target's orbital elements into the Astronomer's Proposal Tool (APT). This allowed possible copy/paste transcription errors from the observer's source of orbital elements data. In order to address this issue, APT has now been improved with the capability to identify targets in and then download orbital elements from JPL Horizons. The observer will first use a target name resolver to choose the intended target from the Horizons database, and then download the orbital elements from Horizons directly into APT. A manual entry option is also still retained if the observer does not wish to use elements from Horizons. This new capability is available for HST observing, and it will also be supported for JWST observing. The poster shows examples of this new interface.

  6. Do as I do: exercise habits of physical therapists, physical therapist assistants, and student physical therapists.

    PubMed

    Chevan, Julia; Haskvitz, Esther M

    2010-05-01

    Physical therapy practitioners are among the many health care professionals who can counsel their patients to address the public health care concern of physical inactivity. Health care providers who are physically active themselves are more likely to counsel patients on the benefits of activity. The purposes of this study were: (1) to examine the leisure-time physical activity habits of physical therapists, physical therapist assistants, and student physical therapists in the United States using Centers for Disease Control and Prevention and American College of Sports Medicine (CDC-ACSM) recommendations and (2) to compare these habits with those of the general population and other health care professionals. A cross-sectional survey design was used. There were 2 data sources. A random sample of American Physical Therapy Association members completed an online survey that included questions about physical activity habits worded in same manner as the leisure-time activities section of the 2005 National Health Interview Survey (NHIS). The final study sample comprised 1,238 participants: 923 physical therapists, 210 student physical therapists, and 105 physical therapist assistants. The 2005 NHIS public use data files were the source for the same information about the general US population and for a subset of health care professionals. Rates of participation in vigorous and moderate physical activity were analyzed. Physical therapists, physical therapist assistants, and student physical therapists exercised at higher rates than adults and health-diagnosing professionals in the 2005 NHIS. Limitations The study may be limited by sampling and response bias. This study identified that physical therapists, physical therapist assistants, and student physical therapists are meeting CDC-ACSM physical activity guidelines at higher rates than the US adult population and health-diagnosing professionals. These rates exceed the physical activity targets set for adults in Healthy

  7. Theme: Physical Science in Agriscience--The New Ag Mech.

    ERIC Educational Resources Information Center

    Buriak, Phil; And Others

    1992-01-01

    Seven theme articles discuss strategies for teaching mechanics, physical sciences in the study of foods, scientific principles in the agricultural curriculum, environmental issues in agriculture, and applied physical sciences. (SK)

  8. Incorporating signal-dependent noise for hyperspectral target detection

    NASA Astrophysics Data System (ADS)

    Morman, Christopher J.; Meola, Joseph

    2015-05-01

    The majority of hyperspectral target detection algorithms are developed from statistical data models employing stationary background statistics or white Gaussian noise models. Stationary background models are inaccurate as a result of two separate physical processes. First, varying background classes often exist in the imagery that possess different clutter statistics. Many algorithms can account for this variability through the use of subspaces or clustering techniques. The second physical process, which is often ignored, is a signal-dependent sensor noise term. For photon counting sensors that are often used in hyperspectral imaging systems, sensor noise increases as the measured signal level increases as a result of Poisson random processes. This work investigates the impact of this sensor noise on target detection performance. A linear noise model is developed describing sensor noise variance as a linear function of signal level. The linear noise model is then incorporated for detection of targets using data collected at Wright Patterson Air Force Base.

  9. Design of a liquid membrane target for high repetition rate neutron generation

    NASA Astrophysics Data System (ADS)

    Poole, Patrick; Andereck, C. David; Storm, Mike; Schumacher, Douglass

    2013-10-01

    Ultra-bright, pulsed, spatially-small sources of energetic neutrons have applications in radiography and non-destructive remote sensing. Neutrons can be generated by a process wherein ions accelerated from a laser-irradiated primary target subsequently bombard a converter material, causing neutron-producing nuclear reactions, such as 7Li(d,n)8Be. Deuterons from this process are suppressed by contamination that builds up on the rear of the solid primary target. To eliminate this issue we propose a self-replenishing liquid membrane target consisting of heavy water and deuterated surfactant, formed in-vacuum within a moveable wire frame. In addition to removing issues associated with solid target positioning and collateral damage, this apparatus provides flow rate and target thickness control, and allows for the high repetition rates required to generate desired neutron fluxes with a portable laser-based system. The apparatus design will be presented, as well as a novel interferometric method that measures the membrane thickness using tightly-focused light. This work was performed with support from DARPA.

  10. Sources of Legal Liability among Physical Education Teachers

    ERIC Educational Resources Information Center

    Babalola, Alla Joseph; Alayode, Ajibua Michael

    2012-01-01

    Legal issues in Physical Education are very germane to sport and physical activity development. Consequently, Physical Education teachers should be involved in studying laws that relates to P.E in the course of their professional preparation. It is worth noting that today, people are becoming more aware of their rights under the law. This has…

  11. On-Line; Special Summer Issue on ICM 74.

    ERIC Educational Resources Information Center

    Zinn, Karl L., Ed.

    1974-01-01

    The proceedings of the 1974 Conference on Instructional Computing in Michigan comprise this special issue of the newsletter on educational use of computers among Michigan colleges and universities. Individual papers were presented on conceptual, technical, and practical aspects of instructional computing in (1) mathematics, (2) the physical and…

  12. Foucault on targets.

    PubMed

    Lynch, John

    2004-01-01

    This paper seeks to gain an insight into the behavior of a large NHS trust, in its attempt to meet a 90 percent patient access target, in a week long national audit in March 2003. Why did individuals act in dramatically different ways to their norm over this period. The work of Michel Foucault is used to explore these issues. The discourses of power, knowledge, discipline and governmentality are identified as key foucaudian themes that offer an alternative interpretation of how individuals behave in their place of work. The importance of the historical context of discourse within the NHS cannot be underestimated in shaping the behavior of individuals and groups today. Power and knowledge permeate NHS organizations through disciplinary practices and dressage. Governmentality seeks to maintain the status quo through disciplinary processes such as national healthcare targets. The natural response of NHS organizations is therefore, to seek order and conformity rather than disorder and conflict.

  13. Assessing physical activity using wearable monitors: measures of physical activity.

    PubMed

    Butte, Nancy F; Ekelund, Ulf; Westerterp, Klaas R

    2012-01-01

    Physical activity may be defined broadly as "all bodily actions produced by the contraction of skeletal muscle that increase energy expenditure above basal level." Physical activity is a complex construct that can be classified into major categories qualitatively, quantitatively, or contextually. The quantitative assessment of physical activity using wearable monitors is grounded in the measurement of energy expenditure. Six main categories of wearable monitors are currently available to investigators: pedometers, load transducers/foot-contact monitors, accelerometers, HR monitors, combined accelerometer and HR monitors, and multiple sensor systems. Currently available monitors are capable of measuring total physical activity as well as components of physical activity that play important roles in human health. The selection of wearable monitors for measuring physical activity will depend on the physical activity component of interest, study objectives, characteristics of the target population, and study feasibility in terms of cost and logistics. Future development of sensors and analytical techniques for assessing physical activity should focus on the dynamic ranges of sensors, comparability for sensor output across manufacturers, and the application of advanced modeling techniques to predict energy expenditure and classify physical activities. New approaches for qualitatively classifying physical activity should be validated using direct observation or recording. New sensors and methods for quantitatively assessing physical activity should be validated in laboratory and free-living populations using criterion methods of calorimetry or doubly labeled water.

  14. The value of physical examination in mental health nursing.

    PubMed

    Martin, Carolyn T

    2016-03-01

    This article explores the use of a physical examination assignment in a mental health general nursing clinical placement course that addresses the poor physical health of people with mental illness and the barriers traditionally impeding health care provision for this population. A descriptive qualitative approach utilizes inductive content analysis to investigate 145 student survey responses. The assignment assists student nurses in understanding that physical and mental well-being are intrinsically linked. Students report increased comfort performing a physical examination on patients with mental illness post assignment. Students' initial bias towards this population was minimized post the clinical assignment. Poor physical health is common among people with mental health problems. Many view the provision of care as a major public health issue. Nurses are the front line caregivers of mental health service consumers and are well positioned to assess their physical needs. Their assessment may be the first step in recognizing health care issues in this population. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. Improving physics education in radiology.

    PubMed

    Hendee, William R

    2007-08-01

    Concern is growing that the physics education of radiologists is flawed and that without knowledge of physics principles and applications, mastery of the technology of medical imaging is impaired. Furthermore, it is proposed that a mastery of imaging technology is necessary to perfect the clinical acumen of radiologists and to preserve the quality, safety, and cost-effectiveness of imaging procedures. These issues were the focus of a multiorganizational educational summit on physics education of radiologists held in January 2006 in Atlanta. Recommendations for improving the physics education and knowledge of radiologists that evolved from this summit are presented here, together with progress made to date on their fulfillment.

  16. Manual physical therapy: we speak gibberish.

    PubMed

    Flynn, Timothy W; Childs, John D; Bell, Stephania; Magel, Jake S; Rowe, Robert H; Plock, Haideh

    2008-03-01

    In December of 2006, the American Academy of Orthopaedic Manual Physical Therapists (AAOMPT) convened a task force to create a framework for standardizing manual physical therapy procedures. The impetus came from many years of frustration with our ability to precisely communicate to each other, as well as to stakeholders outside our profession. To this end, a contribution titled "A Model for Standardizing Manipulation Terminology In Physical Therapy Practice" is published in this issue of the Journal.

  17. Recognizing Physical Disability as a Social Problem.

    ERIC Educational Resources Information Center

    Blake, Charles

    Physical disability is an enormous psychosocio-economic-medical problem that affects over 24 million Americans. Public policy endorses a multi-disciplinary approach in analyzing this issue. Legislation has broadened the meaning of physical disability to include persons with mental and emotional disorders. Some of the costs associated with physical…

  18. Physical and Chemical Strategies for Therapeutic Delivery by Using Polymeric Nanoparticles

    PubMed Central

    Morachis, José M.; Mahmoud, Enas A.

    2012-01-01

    A significant challenge that most therapeutic agents face is their inability to be delivered effectively. Nanotechnology offers a solution to allow for safe, high-dose, specific delivery of pharmaceuticals to the target tissue. Nanoparticles composed of biodegradable polymers can be designed and engineered with various layers of complexity to achieve drug targeting that was unimaginable years ago by offering multiple mechanisms to encapsulate and strategically deliver drugs, proteins, nucleic acids, or vaccines while improving their therapeutic index. Targeting of nanoparticles to diseased tissue and cells assumes two strategies: physical and chemical targeting. Physical targeting is a strategy enabled by nanoparticle fabrication techniques. It includes using size, shape, charge, and stiffness among other parameters to influence tissue accumulation, adhesion, and cell uptake. New methods to measure size, shape, and polydispersity will enable this field to grow and more thorough comparisons to be made. Physical targeting can be more economically viable when certain fabrication techniques are used. Chemical targeting can employ molecular recognition units to decorate the surface of particles or molecular units responsive to diseased environments or remote stimuli. In this review, we describe sophisticated nanoparticles designed for tissue-specific chemical targeting that use conjugation chemistry to attach targeting moieties. Furthermore, we describe chemical targeting using stimuli responsive nanoparticles that can respond to changes in pH, heat, and light. PMID:22544864

  19. Comparative Analysis of State Fish Consumption Advisories Targeting Sensitive Populations

    PubMed Central

    Scherer, Alison C.; Tsuchiya, Ami; Younglove, Lisa R.; Burbacher, Thomas M.; Faustman, Elaine M.

    2008-01-01

    Objective Fish consumption advisories are issued to warn the public of possible toxicological threats from consuming certain fish species. Although developing fetuses and children are particularly susceptible to toxicants in fish, fish also contain valuable nutrients. Hence, formulating advice for sensitive populations poses challenges. We conducted a comparative analysis of advisory Web sites issued by states to assess health messages that sensitive populations might access. Data sources We evaluated state advisories accessed via the National Listing of Fish Advisories issued by the U.S. Environmental Protection Agency. Data extraction We created criteria to evaluate advisory attributes such as risk and benefit message clarity. Data synthesis All 48 state advisories issued at the time of this analysis targeted children, 90% (43) targeted pregnant women, and 58% (28) targeted women of childbearing age. Only six advisories addressed single contaminants, while the remainder based advice on 2–12 contaminants. Results revealed that advisories associated a dozen contaminants with specific adverse health effects. Beneficial health effects of any kind were specifically associated only with omega-3 fatty acids found in fish. Conclusions These findings highlight the complexity of assessing and communicating information about multiple contaminant exposure from fish consumption. Communication regarding potential health benefits conferred by specific fish nutrients was minimal and focused primarily on omega-3 fatty acids. This overview suggests some lessons learned and highlights a lack of both clarity and consistency in providing the breadth of information that sensitive populations such as pregnant women need to make public health decisions about fish consumption during pregnancy. PMID:19079708

  20. Relationship between Attitude toward Target Language Culture Instruction and Pragmatic Comprehension Development

    ERIC Educational Resources Information Center

    Rafieyan, Vahid; Majid, Norazman Bin Abdul; Eng, Lin Siew

    2013-01-01

    Familiarity with the cultural features of the target language society and interest in learning those cultural features are the key factors to determine language learners' level of pragmatic comprehension. To investigate this issue, this study attempted to assess the relationship between attitude toward incorporating target language culture into…

  1. Special issue on network coding

    NASA Astrophysics Data System (ADS)

    Monteiro, Francisco A.; Burr, Alister; Chatzigeorgiou, Ioannis; Hollanti, Camilla; Krikidis, Ioannis; Seferoglu, Hulya; Skachek, Vitaly

    2017-12-01

    Future networks are expected to depart from traditional routing schemes in order to embrace network coding (NC)-based schemes. These have created a lot of interest both in academia and industry in recent years. Under the NC paradigm, symbols are transported through the network by combining several information streams originating from the same or different sources. This special issue contains thirteen papers, some dealing with design aspects of NC and related concepts (e.g., fountain codes) and some showcasing the application of NC to new services and technologies, such as data multi-view streaming of video or underwater sensor networks. One can find papers that show how NC turns data transmission more robust to packet losses, faster to decode, and more resilient to network changes, such as dynamic topologies and different user options, and how NC can improve the overall throughput. This issue also includes papers showing that NC principles can be used at different layers of the networks (including the physical layer) and how the same fundamental principles can lead to new distributed storage systems. Some of the papers in this issue have a theoretical nature, including code design, while others describe hardware testbeds and prototypes.

  2. Evaluating experimental molecular physics studies of radiation damage in DNA*

    NASA Astrophysics Data System (ADS)

    Śmiałek, Małgorzata A.

    2016-11-01

    The field of Atomic and Molecular Physics (AMP) is a mature field exploring the spectroscopy, excitation, ionisation of atoms and molecules in all three phases. Understanding of the spectroscopy and collisional dynamics of AMP has been fundamental to the development and application of quantum mechanics and is applied across a broad range of disparate disciplines including atmospheric sciences, astrochemistry, combustion and environmental science, and in central to core technologies such as semiconductor fabrications, nanotechnology and plasma processing. In recent years the molecular physics also started significantly contributing to the area of the radiation damage at molecular level and thus cancer therapy improvement through both experimental and theoretical advances, developing new damage measurement and analysis techniques. It is therefore worth to summarise and highlight the most prominent findings from the AMP community that contribute towards better understanding of the fundamental processes in biologically-relevant systems as well as to comment on the experimental challenges that were met for more complex investigation targets. Contribution to the Topical Issue "Low-Energy Interactions related to Atmospheric and Extreme Conditions", edited by S. Ptasinska, M. Smialek-Telega, A. Milosavljevic, B. Sivaraman.

  3. Quota sampling in internet research: practical issues.

    PubMed

    Im, Eun-Ok; Chee, Wonshik

    2011-07-01

    Quota sampling has been suggested as a potentially good method for Internet-based research and has been used by several researchers working with Internet samples. However, very little is known about the issues or concerns in using a quota sampling method in Internet research. The purpose of this article was to present the practical issues using quota sampling in an Internet-based study. During the Internet study, the research team recorded all recruitment issues that arose and made written notes indicating the possible reasons for the problems. In addition, biweekly team discussions were conducted for which written records were kept. Overall, quota sampling was effective in ensuring that an adequate number of midlife women were recruited from the targeted ethnic groups. However, during the study process, we encountered the following practical issues using quota sampling: (1) difficulty reaching out to women in lower socioeconomic classes, (2) difficulty ensuring authenticity of participants' identities, (3) participants giving inconsistent answers for the screening questions versus the Internet survey questions, (4) potential problems with a question on socioeconomic status, (5) resentment toward the research project and/or researchers because of rejection, and (6) a longer time and more expense than anticipated.

  4. Polarized deuterium internal target at AmPS (NIKHEF)

    NASA Astrophysics Data System (ADS)

    Ferro-Luzzi, M.; Zhou, Z.-L.; van den Brand, J. F. J.; Bulten, H. J.; Alarcon, R.; van Bakel, N.; Botto, T.; Bouwhuis, M.; van Buuren, L.; Comfort, J.; Doets, M.; Dolfini, S.; Ent, R.; Geurts, D.; Heimberg, P.; Higinbotham, D. W.; de Jager, C. W.; Lang, J.; de Lange, D. J.; Norum, B.; Passchier, I.; Poolman, H. R.; Six, E.; Steijger, J.; Szczerba, D.; Unal, O.; de Vries, H.

    1998-01-01

    We describe the polarized deuterium target internal to the NIKHEF medium-energy electron storage ring. Tensor polarized deuterium was produced in an atomic beam source and injected into a storage cell target. A Breit-Rabi polarimeter was used to monitor the injected atomic beam intensity and polarization. An electrostatic ion-extraction system and a Wien filter were utilized to measure on-line the atomic fraction of the target gas in the storage cell. This device was supplemented with a tensor polarization analyzer using the neutron anisotropy of the 3H(d,n)α reaction at 60 keV. This method allows determining the density-averaged nuclear polarization of the target gas, independent of spatial and temporal variations. We address issues important for polarized hydrogen/deuterium internal targets, such as the effects of spin-exchange collisions and resonant transitions induced by the RF fields of the charged particle beam.

  5. Contingent attentional capture occurs by activated target congruence.

    PubMed

    Ariga, Atsunori; Yokosawa, Kazuhiko

    2008-05-01

    Contingent attentional capture occurs when a stimulus property captures an observer's attention, usually related to the observer's top-down attentional set for target-defining properties. In this study, we examined whether contingent attentional capture occurs for a distractor that does not share the target-defining property at a physical level, but does share that property at an abstract level of representation. In a rapid serial visual presentation stream, we defined the target by color (e.g., a green-colored Japanese kanji character). Before the target onset, we presented a distractor that referred to the target-defining color (e.g., a white-colored character meaning "green"). We observed contingent attentional capture by the distractor, which was reflected by a deficit in identifying the subsequent target. This result suggests that because of the attentional set, stimuli were scanned on the basis of the target-defining property at an abstract semantic level of representation.

  6. Physical and Mental Health Issues among Homeless Youth in British Columbia, Canada: Are they Different from Older Homeless Adults?

    PubMed

    Saddichha, Sahoo; Linden, Isabelle; Krausz, Michael Reinhardt

    2014-09-01

    Youth homelessness is on the rise in North America, yet this vulnerable population is rarely studied and compared with adults. This paper aimed to study the homeless youth and identify specific vulnerabilities, which rendered them different from the adult homeless population. It also aimed to describe the youth homeless population and their significant co-morbidities. DATA WAS DERIVED FROM THE BC HEALTH OF THE HOMELESS STUDY (BCHOHS), CARRIED OUT IN THREE CITIES IN BRITISH COLUMBIA, CANADA: the large urban centre Vancouver (n=250); the mid-sized city and capital of the province Victoria (n=150). Measures included socio-demographic information, the Maudsley Addiction Profile (MAP), the Childhood Trauma Questionnaire (CTQ) and the Mini International Neuropsychiatric Interview (MINI) Plus. Youth constituted 16.5% (n=82) of the homeless population. Compared to the adult homeless, the homeless youth were more often female (55%), were Aboriginal (47.6%), had greater substance abuse of alcohol (70.7%), amphetamines (8.5%) and cannabis (75.6%). A lower prevalence of sexually transmitted diseases (0.2%) and psychotic disorders (13.4%) was also observed. The prevalence of traumatic experiences, other psychiatric disorders and physical illnesses were similar between the adult and homeless youth. Homeless youth have high rates of physical and psychiatric comorbidity, similar to the adult homeless, despite being 20 years younger. An urgent need for interventions that go beyond the standardized ones being offered to homeless populations as a whole, and to derive specific strategies that target this vulnerable population is required.

  7. Zimbabwean Female Participation in Physics: Facets of Identity Formation Considered to Be of Significance by Female Students in Relation to Physics

    ERIC Educational Resources Information Center

    Gudyanga, Anna

    2016-01-01

    The study explored facets of identity formation considered to be of significance by Zimbabwean female adolescent students in physics. Four high schools that were offering physics at A' level in the Midlands Province, in Zimbabwe were targeted. Nine female adolescents doing mathematics and physics and only mathematics were chosen. Data generation…

  8. Informing parent targeted interventions to promote increased physical activity among youth

    USDA-ARS?s Scientific Manuscript database

    This was an invited commentary on the qualitative evaluation of a Canadian public service campaign, ParticipACTION "Think Again" described by Faulkner et al in a special issue of the Journal of Applied Research on Children, Family Well-Being and Social Environments. The campaign aimed to make parent...

  9. Physical Education Teacher Education (PETE) in Canada

    ERIC Educational Resources Information Center

    Melnychuk, Nancy; Robinson, Daniel; Lu, Chunlei; Chorney, David; Randall, Lynn

    2011-01-01

    The purpose of this study was to identify physical education (PE) teacher educators and examine physical education teacher education (PETE) programs presently offered at undergraduate degree-granting Canadian universities. The investigation was conceptualized by issues related to the dislodging of PETE from a central to a marginal role in higher…

  10. Obesity and Physical Inactivity in Rural America

    ERIC Educational Resources Information Center

    Patterson, Paul Daniel; Moore, Charity G.; Probst, Janice C.; Shinogle, Judith Ann

    2004-01-01

    Context and Purpose: Obesity and physical inactivity are common in the United States, but few studies examine this issue within rural populations. The present study uses nationally representative data to study obesity and physical inactivity in rural populations. Methods: Data came from the 1998 National Health Interview Survey Sample Adult and…

  11. A brief history of physics education in the United States

    NASA Astrophysics Data System (ADS)

    Meltzer, David E.; Otero, Valerie K.

    2015-05-01

    In order to provide insight into current physics teaching practices and recommended reforms, we outline the history of physics education in the United States—and the accompanying pedagogical issues and debates—over the period 1860-2014. We identify key events, personalities, and issues for each of ten separate time periods, comparing and contrasting the outlooks and viewpoints of the different eras. This discussion should help physics educators to (1) become aware of previous research in physics education and of the major efforts to transform physics instruction that have taken place in the U.S., (2) place the national reform movements of today, as well as current physics education research, in the context of past efforts, and (3) evaluate the effectiveness of various education transformation efforts of the past, so as better to determine what reform methods might have the greatest chances of success in the future.

  12. Popular Media Representations of Physical Activity among Mothers

    ERIC Educational Resources Information Center

    Sanders, Margaret P.; Dlugonski, Deirdre

    2016-01-01

    Purpose: Many mothers fail to meet the recommended guidelines for physical activity. Popular media magazines targeting mothers provide information about physical activity and health, but little is known about the framing and content of physical activity messages within these sources. The aim of this content analysis was to analyze the framing and…

  13. Affirmative Action in Higher Education in India: Targeting, Catch Up, and Mismatch

    ERIC Educational Resources Information Center

    Frisancho, Veronica; Krishna, Kala

    2016-01-01

    Using detailed data on the 2008 graduating class from an elite engineering institution in India, we evaluate the impact of affirmative action policies in higher education focusing on three issues: targeting, catch up, and mismatch. We find that admission preferences effectively target minority students who are poorer than average displaced…

  14. Geophysical background and as-built target characteristics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Allen, J.W.

    1994-09-01

    The US Department of Energy (DOE) Grand Junction Projects Office (GJPO) has provided a facility for DOE, other Government agencies, and the private sector to evaluate and document the utility of specific geophysical measurement techniques for detecting and defining cultural and environmental targets. This facility is the Rabbit Valley Geophysics Performance Evaluation Range (GPER). Geophysical surveys prior to the fiscal year (FY) 1994 construction of new test cells showed the primary test area to be relatively homogeneous and free from natural or man-made artifacts, which would generate spurious responses in performance evaluation data. Construction of nine new cell areas inmore » Rabbit Valley was completed in June 1994 and resulted in the emplacement of approximately 150 discrete targets selected for their physical and electrical properties. These targets and their geophysical environment provide a broad range of performance evaluation parameters from ``very easy to detect`` to ``challenging to the most advanced systems.`` Use of nonintrusive investigative techniques represents a significant improvement over intrusive characterization methods, such as drilling or excavation, because there is no danger of exposing personnel to possible hazardous materials and no risk of releasing or spreading contamination through the characterization activity. Nonintrusive geophysical techniques provide the ability to infer near-surface structure and waste characteristics from measurements of physical properties associated with those targets.« less

  15. The physical inactivity matrix: lessons from the classification of physical inactivity interventions.

    PubMed

    Kypri, Kypros; Donaldson, Alex; Johnstone, Elizabeth

    2006-05-01

    Physical inactivity (PI), a leading modifiable cause of disease and injury, is endemic in industrialised nations. Although considerable research has been undertaken in this field, we lack a system to synthesise the research literature to inform policy and identify research needs. The aims of this study were to (1) develop a system to classify physical inactivity intervention studies, (2) examine the distribution of PI interventions published in the peer-reviewed health literature using the system, and (3) consider implications for future research. We developed the Physical Inactivity Matrix (PIM), with 12 intervention points, created by the intersection of two dimensions: the intervention target (individual, physical environment and social/cultural environment) and the activity focus (transport, work/school, leisure and consumer). A formal search of the health research literature identified 529 eligible studies and each was classified into one of the 12 cells of the PIM. Most studies were categorised as: individual-leisure (68%), individual-work/school (12%) or social/cultural environment-leisure (13%). Only 4% targeted the physical environment. The findings of this initial application of the PIM support the call for greater investment in policies, interventions and research that focus on the relationship between the environment and PI, and transportation in particular. There would be merit in establishing the inter-rater reliability of the PIM and applying it to a wider variety of studies, including those published in the transportation and urban planning literatures. The PIM could be a useful tool for monitoring trends in research directions and funding levels over time and across countries.

  16. School-Based Methylphenidate Placebo Protocols: Methodological and Practical Issues.

    ERIC Educational Resources Information Center

    Hyman, Irwin A.; Wojtowicz, Alexandra; Lee, Kee Duk; Haffner, Mary Elizabeth; Fiorello, Catherine A.; And Others

    1998-01-01

    Focuses on methodological issues involved in choosing instruments to monitor behavior, once a comprehensive evaluation has suggested trials on Ritalin. Case examples illustrate problems of teacher compliance in filling out measures, supplying adequate placebos, and obtaining physical cooperation. Emerging school-based methodologies are discussed…

  17. PREFACE: Progress in the ITER Physics Basis

    NASA Astrophysics Data System (ADS)

    Ikeda, K.

    2007-06-01

    I would firstly like to congratulate all who have contributed to the preparation of the `Progress in the ITER Physics Basis' (PIPB) on its publication and express my deep appreciation of the hard work and commitment of the many scientists involved. With the signing of the ITER Joint Implementing Agreement in November 2006, the ITER Members have now established the framework for construction of the project, and the ITER Organization has begun work at Cadarache. The review of recent progress in the physics basis for burning plasma experiments encompassed by the PIPB will be a valuable resource for the project and, in particular, for the current Design Review. The ITER design has been derived from a physics basis developed through experimental, modelling and theoretical work on the properties of tokamak plasmas and, in particular, on studies of burning plasma physics. The `ITER Physics Basis' (IPB), published in 1999, has been the reference for the projection methodologies for the design of ITER, but the IPB also highlighted several key issues which needed to be resolved to provide a robust basis for ITER operation. In the intervening period scientists of the ITER Participant Teams have addressed these issues intensively. The International Tokamak Physics Activity (ITPA) has provided an excellent forum for scientists involved in these studies, focusing their work on the high priority physics issues for ITER. Significant progress has been made in many of the issues identified in the IPB and this progress is discussed in depth in the PIPB. In this respect, the publication of the PIPB symbolizes the strong interest and enthusiasm of the plasma physics community for the success of the ITER project, which we all recognize as one of the great scientific challenges of the 21st century. I wish to emphasize my appreciation of the work of the ITPA Coordinating Committee members, who are listed below. Their support and encouragement for the preparation of the PIPB were

  18. Tendinopathy: Evidence-Informed Physical Therapy Clinical Reasoning.

    PubMed

    Vicenzino, Bill

    2015-11-01

    Patients presenting with pain at the tendon, which is associated with physical tasks and activities that specifically load that tendon, are at the center of this special issue. The current terminology for a symptomatic tendon presentation is tendinopathy, as this does not denote an underlying pathology, but rather signals that all is not well in the tendon. Tendinopathy is a prevalent and substantial problem, as it interferes with a person's capacity to lead a physically active and healthy life, which has a considerable flow-on effect on society in general. This issue deals with the contemporary physical therapy management of tendinopathy by providing a mix of evidence review and clinical expert opinion on commonly presenting tendinopathies of the lower and upper limbs. J Orthop Sports Phys Ther 2015;45(11):816-818. doi:10.2519/jospt.2015.0110.

  19. Physical activity interventions using mass media, print media, and information technology.

    PubMed

    Marcus, B H; Owen, N; Forsyth, L H; Cavill, N A; Fridinger, F

    1998-11-01

    Media-based physical activity interventions include a variety of print, graphic, audiovisual, and broadcast media programs intended to influence behavior change. New information technology allows print to be delivered in personalized, interactive formats that may enhance efficacy. Media-based interventions have been shaped by conceptual models from health education, Social Cognitive Theory, the Transtheoretical Model, and Social Marketing frameworks. We reviewed 28 studies of media-based interventions of which seven were mass media campaigns at the state or national level and the remaining 21 were delivered through health care, the workplace, or in the community. Recall of mass-media messages generally was high, but mass-media campaigns had very little impact on physical activity behavior. Interventions using print and/or telephone were effective in changing behavior in the short term. Studies in which there were more contacts and interventions tailored to the target audience were most effective. A key issue for research on media-based physical activity interventions is reaching socially disadvantaged groups for whom access, particularly to new forms of communication technology, may be limited. There is a clear need for controlled trials comparing different forms and intensities of media-based physical activity interventions. Controlled studies of personalized print, interactive computer-mediated programs, and web-based formats for program delivery also are needed. The integration of media-based methods into public and private sector service delivery has much potential for innovation.

  20. A qualitative theory guided analysis of stroke survivors' perceived barriers and facilitators to physical activity.

    PubMed

    Nicholson, Sarah L; Donaghy, Marie; Johnston, Marie; Sniehotta, Falko F; van Wijck, Frederike; Johnston, Derek; Greig, Carolyn; McMurdo, Marion E T; Mead, Gillian

    2014-01-01

    After stroke, physical activity and physical fitness levels are low, impacting on health, activity and participation. It is unclear how best to support stroke survivors to increase physical activity. Little is known about the barriers and facilitators to physical activity after stroke. Thus, our aim was to explore stroke survivors' perceived barriers and facilitators to physical activity. Semi-structured interviews with 13 ambulatory stroke survivors exploring perceived barriers and facilitators to physical activity post stroke were conducted in participants' homes, audio-recorded and transcribed verbatim. The Theoretical Domains Framework (TDF) informed content analysis of the interview transcripts. Data saturation was reached after interviews with 13 participants (median age of 76 years (inter-quartile range (IQR) = 69-83 years). The median time since stroke was 345 d (IQR = 316-366 d). The most commonly reported TDF domains were "beliefs about capabilities", "environmental context and resources" and "social influence". The most commonly reported perceived motivators were: social interaction, beliefs of benefits of exercise, high self-efficacy and the necessity of routine behaviours. The most commonly reported perceived barriers were: lack of professional support on discharge from hospital and follow-up, transport issues to structured classes/interventions, lack of control and negative affect. Stroke survivors perceive several different barriers and facilitators to physical activity. Stroke services need to address barriers to physical activity and to build on facilitators to promote physical activity after stroke. Physical activity post stroke can improve physical fitness and function, yet physical activity remains low among stroke survivors. Understanding stroke survivors' perceived barriers and facilitators to physical activity is essential to develop targeted interventions to increase physical activity. Beliefs about capabilities, environmental

  1. PREFACE: Celebrating 100 years of superconductivity: special issue on the iron-based superconductors Celebrating 100 years of superconductivity: special issue on the iron-based superconductors

    NASA Astrophysics Data System (ADS)

    Crabtree, George; Greene, Laura; Johnson, Peter

    2011-12-01

    In honor of this year's 100th anniversary of the discovery of superconductivity, this special issue of Reports on Progress in Physics is a dedicated issue to the 'iron-based superconductors'—a new class of high-temperature superconductors that were discovered in 2008. This is the first time the journal has generated a 'theme issue', and we provide this to the community to provide a 'snapshot' of the present status, both for researchers working in this fast-paced field, and for the general physics community. Reports on Progress in Physics publishes three classes of articles—comprehensive full Review Articles, Key Issues Reviews and, most recently, Reports on Progress articles that recount the current status of a rapidly evolving field, befitting of the articles in this special issue. It has been an exciting year for superconductivity—there have been numerous celebrations for this centenary recounting the fascinating history of this field, from seven Nobel prizes to life-saving discoveries that brought us medically useful magnetic resonance imaging. The discovery of a completely new class of high-temperature superconductors, whose mechanism remains as elusive as the cuprates discovered in 1986, has injected a new vitality into this field, and this year those new to the field were provided with the opportunity of interacting with those who have enjoyed a long history in superconductivity. Furthermore, as high-density current carriers with little or no power loss, high-temperature superconductors offer unique solutions to fundamental grid challenges of the 21st century and hold great promise in addressing our global energy challenges. The complexity and promise of these materials has caused our community to more freely share our ideas and results than ever before, and it is gratifying to see how we have grown into an enthusiastic global network to advance the field. This invited collection is true to this agenda and we are delighted to have received contributions

  2. Understanding Older Adults' Physical Activity Behavior: A Multi-Theoretical Approach

    ERIC Educational Resources Information Center

    Grodesky, Janene M.; Kosma, Maria; Solmon, Melinda A.

    2006-01-01

    Physical inactivity is a health issue with serious consequences for older adults. Investigating physical activity promotion within a multi-theoretical approach may increase the predictive strength of physical activity determinants and facilitate the development and implementation of effective interventions for older adults. This article examines…

  3. Heavy-Ion Physics at a Fixed-Target Experiment Using the LHC Proton and Lead Beams (AFTER@LHC): Feasibility Studies for Quarkonium and Drell-Yan Production

    NASA Astrophysics Data System (ADS)

    Trzeciak, B.; Da Silva, C.; Ferreiro, E. G.; Hadjidakis, C.; Kikola, D.; Lansberg, J. P.; Massacrier, L.; Seixas, J.; Uras, A.; Yang, Z.

    2017-09-01

    We outline the case for heavy-ion-physics studies using the multi-TeV lead LHC beams in the fixed-target mode. After a brief contextual reminder, we detail the possible contributions of AFTER@LHC to heavy-ion physics with a specific emphasis on quarkonia. We then present performance simulations for a selection of observables. These show that Υ (nS), J/ψ and ψ (2S) production in heavy-ion collisions can be studied in new energy and rapidity domains with the LHCb and ALICE detectors. We also discuss the relevance to analyse the Drell-Yan pair production in asymmetric nucleus-nucleus collisions to study the factorisation of the nuclear modification of partonic densities and of further quarkonium states to restore their status of golden probes of the quark-gluon plasma formation.

  4. Aptamers as inhibitors of target proteins.

    PubMed

    Missailidis, S; Hardy, A

    2009-08-01

    Aptamers as inhibitors of proteins in therapeutic applications offer great advantages over their antibody counterparts and the promise to be developed into the next generation therapeutic agents. However, the control of aptamer intellectual property (IP) by two major players has made aptamers an area difficult to operate and often off-putting for academic and commercial organisations. Yet, their great potential is keeping aptamers at the research forefront, with one aptamer in the clinic and various at different stages of clinical trials. To provide a comprehensive review of the aptamer IP landscape and the issues associated with aptamer therapeutics against protein targets. Extensive review of the scientific and patent literature. Following our experience in developing, patenting and commercialising our aptamers against MUC1 and an extensive review of the literature, we have identified a variety of issues pertaining to the development of aptamers against protein targets for therapeutic applications, their patenting and granting of patents, the original IP holders and their policy, as well as the current market and traits. Despite a slow start, aptamers have been developed against various therapeutic proteins and offer the promise of providing a novel generation of therapeutic entities with a variety of applications.

  5. Beyond Physics: A Case for Far Transfer

    ERIC Educational Resources Information Center

    Forsyth, Benjamin Robert

    2012-01-01

    This is a case study of a physics undergraduate who claimed that he "uses physics to understand other subjects." This statement suggested that this student could describe issues concerning the transfer of learning and especially instances of far transfer. Detailed instances of far transfer have been difficult to replicate in lab settings.…

  6. Targeting active cancer cells with smart bullets.

    PubMed

    Martel, Sylvain

    2017-03-01

    Paul Ehrlich's 'magic bullet' concept has stimulated research for therapeutic agents with the capability to go straight to their intended targets. The 'magic bullet' concept is still considered the ultimate approach to maximize the therapeutic effects of a given therapeutic agent without affecting nontargeted tissues. But so far, there has never been a therapeutic agent or a delivery system that goes straight to the target in the body, and no approach has provided anything better than just a few percents of the total administered dose reaching the intended target sites. But engineering principles can transform systematically circulating vectors that so far were based primarily on physical characteristics and biochemical principles alone, as smart therapeutic agents with the required propulsion-navigation-homing capabilities to enable them to go straight to their intended targets.

  7. Current Issues in the Evaluation and Treatment of Sexual Disturbance.

    ERIC Educational Resources Information Center

    Beutler, Larry E.

    1986-01-01

    Discusses causes of sexual disturbance, assessment of sexual dysfunction, treatment of sexual dysfunction, psychological issues associated with chronic physical illness and sexual behavior, theory and treatment in child molestation, and the psychosocial outcomes of sex reassignment surgery. (BL)

  8. 100 Years of Attempts to Transform Physics Education

    NASA Astrophysics Data System (ADS)

    Otero, Valerie K.; Meltzer, David E.

    2016-12-01

    As far back as the late 1800s, U.S. physics teachers expressed many of the same ideas about physics education reform that are advocated today. However, several popular reform efforts eventually failed to have wide impact, despite strong and enthusiastic support within the physics education community. Broad-scale implementation of improved instructional models today may be just as elusive as it has been in the past, and for similar reasons. Although excellent instructional models exist and have been available for decades, effective and scalable plans for transforming practice on a national basis have yet to be developed and implemented. Present-day teachers, education researchers, and policy makers can find much to learn from past efforts, both in their successes and their failures. To this end, we present a brief outline of some key ideas in U.S. physics education during the past 130 years. We address three core questions that are prominent in the literature: (a) Why and how should physics be taught? (b) What physics should be taught? (c) To whom should physics be taught? Related issues include the role of the laboratory and attempts to make physics relevant to everyday life. We provide here only a brief summary of the issues and debates found in primary-source literature; an extensive collection of historical resources on physics education is available at https://sites.google.com/site/physicseducationhistory/home.

  9. A Max-Flow Based Algorithm for Connected Target Coverage with Probabilistic Sensors

    PubMed Central

    Shan, Anxing; Xu, Xianghua; Cheng, Zongmao; Wang, Wensheng

    2017-01-01

    Coverage is a fundamental issue in the research field of wireless sensor networks (WSNs). Connected target coverage discusses the sensor placement to guarantee the needs of both coverage and connectivity. Existing works largely leverage on the Boolean disk model, which is only a coarse approximation to the practical sensing model. In this paper, we focus on the connected target coverage issue based on the probabilistic sensing model, which can characterize the quality of coverage more accurately. In the probabilistic sensing model, sensors are only be able to detect a target with certain probability. We study the collaborative detection probability of target under multiple sensors. Armed with the analysis of collaborative detection probability, we further formulate the minimum ϵ-connected target coverage problem, aiming to minimize the number of sensors satisfying the requirements of both coverage and connectivity. We map it into a flow graph and present an approximation algorithm called the minimum vertices maximum flow algorithm (MVMFA) with provable time complex and approximation ratios. To evaluate our design, we analyze the performance of MVMFA theoretically and also conduct extensive simulation studies to demonstrate the effectiveness of our proposed algorithm. PMID:28587084

  10. A Max-Flow Based Algorithm for Connected Target Coverage with Probabilistic Sensors.

    PubMed

    Shan, Anxing; Xu, Xianghua; Cheng, Zongmao; Wang, Wensheng

    2017-05-25

    Coverage is a fundamental issue in the research field of wireless sensor networks (WSNs). Connected target coverage discusses the sensor placement to guarantee the needs of both coverage and connectivity. Existing works largely leverage on the Boolean disk model, which is only a coarse approximation to the practical sensing model. In this paper, we focus on the connected target coverage issue based on the probabilistic sensing model, which can characterize the quality of coverage more accurately. In the probabilistic sensing model, sensors are only be able to detect a target with certain probability. We study the collaborative detection probability of target under multiple sensors. Armed with the analysis of collaborative detection probability, we further formulate the minimum ϵ -connected target coverage problem, aiming to minimize the number of sensors satisfying the requirements of both coverage and connectivity. We map it into a flow graph and present an approximation algorithm called the minimum vertices maximum flow algorithm (MVMFA) with provable time complex and approximation ratios. To evaluate our design, we analyze the performance of MVMFA theoretically and also conduct extensive simulation studies to demonstrate the effectiveness of our proposed algorithm.

  11. PREFACE: 1st Tensor Polarized Solid Target Workshop

    NASA Astrophysics Data System (ADS)

    2014-10-01

    These are the proceedings of the first Tensor Spin Observables Workshop that was held in March 2014 at the Thomas Jefferson National Accelerator Facility in Newport News, Virginia. The conference was convened to study the physics that can be done with the recently approved E12-13-011 polarized target. A tensor polarized target holds the potential of initiating a new generation of tensor spin physics at Jefferson Lab. Experiments which utilize tensor polarized targets can help clarify how nuclear properties arise from partonic degrees of freedom, provide unique insight into short-range correlations and quark angular momentum, and also help pin down the polarization of the quark sea with a future Electron Ion Collider. This three day workshop was focused on tensor spin observables and the associated tensor target development. The workshop goals were to stimulate progress in the theoretical treatment of polarized spin-1 systems, foster the development of new proposals, and to reach a consensus on the optimal polarized target configuration for the tensor spin program. The workshop was sponsored by the University of New Hampshire, the Jefferson Science Associates, Florida International University, and Jefferson Lab. It was organized by Karl Slifer (chair), Patricia Solvignon, and Elena Long of the University of New Hampshire, Douglas Higinbotham and Christopher Keith of Jefferson Lab, and Misak Sargsian of the Florida International University. These proceedings represent the effort put forth by the community to begin exploring the possibilities that a high-luminosity, high-tensor polarized solid target can offer.

  12. Professional Development Workshops for Student Teachers: An Issue of Concern

    ERIC Educational Resources Information Center

    Hsu, Amy; Malkin, Fran

    2013-01-01

    Professional development programs are critical in addressing the needs of teacher education students and graduates. In an effort to best meet the desired needs and wants of these new educators, professional development opportunities must target essential issues. This study examines topics including classroom management, exceptional children,…

  13. Ethical issues in primary health care: a survey of practitioners' perceptions.

    PubMed

    Robillard, H M; High, D M; Sebastian, J G; Pisaneschi, J I; Perritt, L J; Mahler, D M

    1989-01-01

    While most health care is provided at the primary care level, little research has been done to document the ethical issues of such care. A stratified random sample of 702 physicians, nurses, physical therapist, and physician assistants within one southeastern state was surveyed to determine the frequency of ethical issues in primary care. The most frequently occurring issue concerned moral decisions about the amount of time to spend with each patient. A comparison of physician and nonphysician professional groups revealed significant differences in frequencies of the issues. Age had a slight impact on the responses, while gender, religion, and region of practice had none. The study showed that the most frequently occurring issues are pragmatic, not dramatic, and center on patient self-determination, adequacy of care and professional responsibility, and distribution of resources.

  14. EDITORIAL: 50th anniversary issue

    NASA Astrophysics Data System (ADS)

    Beddoe, Alun H.

    2006-07-01

    In July 1956, 50 years ago, the first issue of Physics in Medicine and Biology (PMB) was published. It was subtitled The Journal of the Hospital Physicists' Association and published in association with the Philosophical Magazine by Taylor and Francis. Subscriptions were £1 per part or £3 10s for an annual subscription. The Editor, Professor J E Roberts, prefaced the first issue with a cautious editorial noting: The appearance of a new journal is usually greeted with mixed feelings by scientific workers, a common response being that there are far too many journals already. Justification for a new publication is only possible if there is a clearly defined gap in the publishing facilities available to workers in a particular scientific field.... Professor Roberts ended by seeking support from the scientific community for the new venture. He certainly got it! From a tentative few hundred pages in four issues a year for the first few years, the journal is now issued twice monthly with nearly 8000 pages expected in volume 51. In this anniversary issue we have invited some 28 senior authors to submit papers on a range of subjects spanning the discipline. We decided that to be an author one had to be old, but age was not to be the only criterion! Indeed readers will recognize all names as major contributors to both the development of medical physics and the success of PMB. Authors were not asked to write formal topical reviews of the state-of-the-art of the sub-disciplines which make up medical physics, but rather to present short historical reviews, didactic in style, perhaps highlighting the role of PMB in the development of their fields. Nevertheless, other than a page limit (which many subsequently ignored!) no formal format was imposed on authors, so what follows is a range of contributions from the almost conversational, personal statement to the more formal and familiar scientific paper. Whatever the writing style we are confident that readers will gain some

  15. Target- and Effect-Directed Actions towards Temporal Goals: Similar Mechanisms?

    ERIC Educational Resources Information Center

    Walter, Andrea M.; Rieger, Martina

    2012-01-01

    The goal of an action can consist of generating a change in the environment (to produce an effect) or changing one's own situation in the environment (to move to a physical target). To investigate whether the mechanisms of effect-directed and target-directed action control are similar, participants performed continuous reversal movements. They…

  16. Attendant Care for College Students with Physical Disabilities Using Wheelchairs: Transition Issues and Experiences

    ERIC Educational Resources Information Center

    Burwell, Nequel R.; Wessel, Roger D.; Mulvihill, Thalia

    2015-01-01

    From preschool through high school, accommodation and success, rather than self-advocacy and student development, are the predominant frameworks for students with physical disabilities. Many students with physical disabilities who use wheelchairs are assisted by their family members with daily life activities such as getting out of bed, showering,…

  17. Polarized deuterium internal target at AmPS (NIKHEF)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ferro-Luzzi, M.; NIKHEF, P.O. Box 41882, 1009 DB Amsterdam; Zhou, Z.-L.

    1998-01-20

    We describe the polarized deuterium target internal to the NIKHEF medium-energy electron storage ring. Tensor polarized deuterium was produced in an atomic beam source and injected into a storage cell target. A Breit-Rabi polarimeter was used to monitor the injected atomic beam intensity and polarization. An electrostatic ion-extraction system and a Wien filter were utilized to measure on-line the atomic fraction of the target gas in the storage cell. This device was supplemented with a tensor polarization analyzer using the neutron anisotropy of the {sup 3}H(d,n){alpha} reaction at 60 keV. This method allows determining the density-averaged nuclear polarization of themore » target gas, independent of spatial and temporal variations. We address issues important for polarized hydrogen/deuterium internal targets, such as the effects of spin-exchange collisions and resonant transitions induced by the RF fields of the charged particle beam.« less

  18. In this issue--engineering the immune system to fight cancer and infections.

    PubMed

    Bot, Adrian

    2011-01-01

    As the immune system essentially evolved to fight off or keep at bay life-threatening infectious agents rather than cancer, the question remains as to how to best redeploy it for the treatment of a broader range of diseases. This is reflected by an unprecedented diversification of platform technologies in development, facilitated by rapid progress in biotechnology. In this issue, we host several contributions outlining major efforts in developing novel immune interventions spanning antigen-specific vaccination, non-antigen-targeted immune intervention, genetically engineered lymphocytes, and ultraspecific antigen-targeted ligands. In addition, the journal is hosting in this issue, two reviews discussing the complex matter and dynamic balance between immunity and viral infections, as the concept of fine modulation of that balance still carries the promise of yielding novel therapies.

  19. Development of Field-Reversed Configuration Plasma Gun Formation Techniques for Magnetized Target Fusion

    NASA Astrophysics Data System (ADS)

    Lynn, Alan; Gilmore, Mark; Wynkoop, Tyler; Intrator, Thomas; Weber, Thomas

    2012-10-01

    Magnetized Target Fusion (MTF) is an innovative approach for a relatively fast and cheap path to the production of fusion energy that utilizes magnetic confinement to assist in the compression of a hot plasma to thermonuclear conditions by an external driver. Los Alamos National Laboratory (LANL) is currently pursing demonstration of the MTF concept via compression of an FRC (field-reversed configuration) plasma by a metal liner z-pinch in conjunction with the Air Force Research Laboratory in Albuquerque, NM. A key physics issue for the FRC as an MTF target lies in the initial pre-ionization (PI) stage. The PI formation process determines the amount of magnetic flux that can be trapped to form the FRC. This trapped flux plays an important role in the FRC's final equilibrium, transport, and stability properties. It also provides the route to greatest potential gains in FRC lifetime, which is essential to provide enough time to translate and compress the FRC effectively. In conjunction with LANL we plan to test and characterize a new system to improve the initial PI plasma formation. This system will use an array of plasma guns to form the initial plasma. Initial characterization of the plasma gun behavior will be presented.

  20. The implementation of physical safety system in bunker of the electron beam accelerator

    NASA Astrophysics Data System (ADS)

    Ahmad, M. A.; Hashim, S. A.; Ahmad, A.; Leo, K. W.; Chulan, R. M.; Dalim, Y.; Baijan, A. H.; Zain, M. F.; Ros, R. C.

    2017-01-01

    This paper describes the implementation of physical safety system for the new low energy electron beam (EB) accelerator installed at Block 43T Nuclear Malaysia. The low energy EB is a locally designed and developed with a target energy of 300 keV. The issues on radiation protection have been addressed by the installation of radiation shielding in the form of a bunker and installation radiation monitors. Additional precaution is needed to ensure that personnel are not exposed to radiation and other physical hazards. Unintentional access to the radiation room can cause serious hazard and hence safety features must be installed to prevent such events. In this work we design and built a control and monitoring system for the shielding door. The system provides signals to the EB control panel to allow or prevent operation. The design includes limit switches, key-activated switches and emergency stop button and surveillance camera. Entry procedure is also developed as written record and for information purposes. As a result, through this safety implementation human error will be prevented, increase alertness during operation and minimizing unnecessary radiation exposure.

  1. Preface of the special issue: "Vertical coupling in the atmosphere-ionosphere system: Recent progress"

    NASA Astrophysics Data System (ADS)

    2018-06-01

    This special issue of the Journal of Atmospheric and Solar-Terrestrial Physics comprises papers dealing with investigation of the coupling phenomena in the neutral Atmosphere-Ionosphere System of the Earth. The core of the special issue is formed by the recent results presented during the 6th IAGA/ICMA/SCOSTEP Workshop on the Vertical Coupling in the Neutral Atmosphere-Ionosphere System held in Taipei, Taiwan, July 2016. Workshops are organized with a substantial support of the scientific international bodies, such as the International Association of Geomagnetism and Aeronomy (IAGA), International Commission for the Middle Atmosphere (ICMA) and Committee on Solar-Terrestrial Physics (SCOSTEP). The special issue includes also recent results of other members of the aeronomic research community. Hence it represents the state-of-art knowledge in the associated research fields.

  2. Systematic, Evidence-Based Review of Exercise, Physical Activity, and Physical Fitness Effects on Cognition in Persons with Multiple Sclerosis.

    PubMed

    Sandroff, Brian M; Motl, Robert W; Scudder, Mark R; DeLuca, John

    2016-09-01

    Cognitive dysfunction is highly prevalent, disabling, and poorly-managed in persons with multiple sclerosis (MS). Recent evidence suggests that exercise might have beneficial effects on cognition in this population. The current systematic, evidence-based review examined the existing literature on exercise, physical activity, and physical fitness effects on cognition in MS to accurately describe the current status of the field, offer recommendations for clinicians, and identify study-specific and participant-specific characteristics for providing future direction for ongoing MS research. We performed an open-dated search of Medline, PsychInfo, and CINAHL in December 2015. The search strategy involved using the terms 'exercise' OR 'physical activity' OR 'physical fitness' OR 'aerobic' OR 'resistance' OR 'balance' OR 'walking' OR 'yoga' OR 'training' OR 'rehabilitation' AND 'multiple sclerosis'. Articles were eliminated from the systematic review if it was a review article, theoretical paper, or textbook chapter; did not involve persons with MS; involved only persons with pediatric-onset MS; did not involve neuropsychological outcomes; did not include empirical data to evaluate outcomes; involved pharmacological interventions; or was not available in English. The selected articles were first classified as examining exercise, physical activity, or physical fitness, and were then randomly assigned to 2 independent reviewers who rated each article for level of evidence based on American Academy of Neurology criteria. Reviewers further completed a table to characterize important elements of each study (i.e., intervention characteristics), the cognitive domain(s) that were targeted, participant-specific characteristics, outcome measures, and study results. The present review resulted in 26 studies on the effects of exercise, physical activity, and physical fitness on cognition in persons with MS. This included 1 Class I study, 3 Class II studies, 8 Class III studies, and

  3. Changing strategies for target therapy in gastric cancer.

    PubMed

    Lee, Suk-Young; Oh, Sang Cheul

    2016-01-21

    In spite of a worldwide decrease in the incidence of gastric cancer, this malignancy still remains one of the leading causes of cancer mortality. Great efforts have been made to improve treatment outcomes in patients with metastatic gastric cancer, and the introduction of trastuzumab has greatly improved the overall survival. The trastuzumab treatment took its first step in opening the era of molecular targeted therapy, however several issues still need to be resolved to increase the efficacy of targeted therapy. Firstly, many patients with metastatic gastric cancer who receive trastuzumab in combination with chemotherapeutic agents develop resistance to the targeted therapy. Secondly, many clinical trials testing novel molecular targeted agents with demonstrated efficacy in other malignancies have failed to show benefit in patients with metastatic gastric cancer, suggesting the importance of the selection of appropriate indications according to molecular characteristics in application of targeted agents. Herein, we review the molecular targeted agents currently approved and in use, and clinical trials in patients with metastatic gastric cancer, and demonstrate the limitations and future direction in treatment of advanced gastric cancer.

  4. Physics at COSY-Juelich

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stroeher, Hans

    2011-10-21

    COSY, a storage and cooler synchrotron, which is fed by an injector cyclotron, is operated at Forschungszentrum Juelich (Germany). It provides phase space cooled polarized or unpolarized beams of protons and deuterons with momenta between 0.3 and 3.7 GeV/c for internal experiments and to external target stations. The major experimental facilities, used for the ongoing physics program, are ANKE and WASA (internal) and TOF (external). A new internal target station to investigate polarization build-up by spin-filtering (PAX) has recently been commissioned. COSY is the machine for hadron spin physics on a world-wide scale, which is also used for tests inmore » conjunction with plans to build a dedicated storage ring for electric dipole moment (EDM) measurements of proton, deuteron and {sup 3}He. In this contribution recent results as well as future plans are summarized.« less

  5. Making the Invisible Visible: A Methodological and a Substantive Issue

    ERIC Educational Resources Information Center

    Dagley, Valerie

    2004-01-01

    This article discusses the issue of "making the invisible visible" from a methodological and a substantive viewpoint. The ideas emerged from a doctoral research study into individual target setting with middle ability students in an English secondary school. The students involved had been identified by assessments as "average"…

  6. Online surveys for BGLT research: issues and techniques.

    PubMed

    Riggle, Ellen D B; Rostosky, Sharon S; Reedy, C Stuart

    2005-01-01

    Online surveys are becoming increasingly popular for accessing less visible and decentralized populations, including bisexual, gay, lesbian and transgender (BGLT) populations. Advances in technology and convenience for the both the researcher and the participant have facilitated this trend. In this paper, we explore issues related to conducting BGLT survey research online, such as making decisions about survey formats, target populations and recruitment, compensation, access.

  7. Artificial intelligence issues related to automated computing operations

    NASA Technical Reports Server (NTRS)

    Hornfeck, William A.

    1989-01-01

    Large data processing installations represent target systems for effective applications of artificial intelligence (AI) constructs. The system organization of a large data processing facility at the NASA Marshall Space Flight Center is presented. The methodology and the issues which are related to AI application to automated operations within a large-scale computing facility are described. Problems to be addressed and initial goals are outlined.

  8. An Introduction to Atmospheric Physics

    NASA Astrophysics Data System (ADS)

    Andrews, David G.

    2000-09-01

    This advanced undergraduate textbook clearly details how physics can be used to understand many important aspects of atmospheric behavior. Coverage presents a broad overview of atmospheric physics, including atmospheric thermodynamics, radiative transfer, atmospheric fluid dynamics and elementary atmospheric chemistry. Armed with an understanding of these topics, the interested student will be able to grasp the essential physics behind issues of current concern, such as the enhanced greenhouse effect and associated questions of climate change, the Antarctic ozone hole and global ozone depletion, as well as more familiar processes such as the formation of raindrops and the development of weather systems. This introductory textbook is ideal for advanced undergraduates studying atmospheric physics as part of physics, meteorology or environmental science courses. It will also be useful for graduate students studying atmospheric physics for the first time and for students of applied mathematics, physical chemistry and engineering who have an interest in the atmosphere.

  9. Cytotoxic T cells use mechanical force to potentiate target cell killing

    PubMed Central

    Basu, Roshni; Whitlock, Benjamin M.; Husson, Julien; Le Floc’h, Audrey; Jin, Weiyang; Oyler-Yaniv, Alon; Dotiwala, Farokh; Giannone, Gregory; Hivroz, Claire; Biais, Nicolas; Lieberman, Judy; Kam, Lance C.; Huse, Morgan

    2016-01-01

    SUMMARY The immunological synapse formed between a cytotoxic T lymphocyte (CTL) and an infected or transformed target cell is a physically active structure capable of exerting mechanical force. Here, we investigated whether synaptic forces promote the destruction of target cells. CTLs kill by secreting toxic proteases and the pore forming protein perforin into the synapse. Biophysical experiments revealed a striking correlation between the magnitude of force exertion across the synapse and the speed of perforin pore formation on the target cell, implying that force potentiates cytotoxicity by enhancing perforin activity. Consistent with this interpretation, we found that increasing target cell tension augmented pore formation by perforin and killing by CTLs. Our data also indicate that CTLs coordinate perforin release and force exertion in space and time. These results reveal an unappreciated physical dimension to lymphocyte function and demonstrate that cells use mechanical forces to control the activity of outgoing chemical signals. PMID:26924577

  10. Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing.

    PubMed

    Basu, Roshni; Whitlock, Benjamin M; Husson, Julien; Le Floc'h, Audrey; Jin, Weiyang; Oyler-Yaniv, Alon; Dotiwala, Farokh; Giannone, Gregory; Hivroz, Claire; Biais, Nicolas; Lieberman, Judy; Kam, Lance C; Huse, Morgan

    2016-03-24

    The immunological synapse formed between a cytotoxic T lymphocyte (CTL) and an infected or transformed target cell is a physically active structure capable of exerting mechanical force. Here, we investigated whether synaptic forces promote the destruction of target cells. CTLs kill by secreting toxic proteases and the pore forming protein perforin into the synapse. Biophysical experiments revealed a striking correlation between the magnitude of force exertion across the synapse and the speed of perforin pore formation on the target cell, implying that force potentiates cytotoxicity by enhancing perforin activity. Consistent with this interpretation, we found that increasing target cell tension augmented pore formation by perforin and killing by CTLs. Our data also indicate that CTLs coordinate perforin release and force exertion in space and time. These results reveal an unappreciated physical dimension to lymphocyte function and demonstrate that cells use mechanical forces to control the activity of outgoing chemical signals. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. MFP scanner diagnostics using a self-printed target to measure the modulation transfer function

    NASA Astrophysics Data System (ADS)

    Wang, Weibao; Bauer, Peter; Wagner, Jerry; Allebach, Jan P.

    2014-01-01

    In the current market, reduction of warranty costs is an important avenue for improving profitability by manufacturers of printer products. Our goal is to develop an autonomous capability for diagnosis of printer and scanner caused defects with mid-range laser multifunction printers (MFPs), so as to reduce warranty costs. If the scanner unit of the MFP is not performing according to specification, this issue needs to be diagnosed. If there is a print quality issue, this can be diagnosed by printing a special test page that is resident in the firmware of the MFP unit, and then scanning it. However, the reliability of this process will be compromised if the scanner unit is defective. Thus, for both scanner and printer image quality issues, it is important to be able to properly evaluate the scanner performance. In this paper, we consider evaluation of the scanner performance by measuring its modulation transfer function (MTF). The MTF is a fundamental tool for assessing the performance of imaging systems. Several ways have been proposed to measure the MTF, all of which require a special target, for example a slanted-edge target. It is unacceptably expensive to ship every MFP with such a standard target, and to expect that the customer can keep track of it. To reduce this cost, in this paper, we develop new approach to this task. It is based on a self-printed slanted-edge target. Then, we propose algorithms to improve the results using a self-printed slanted-edge target. Finally, we present experimental results for MTF measurement using self-printed targets and compare them to the results obtained with standard targets.

  12. Special Issue: Big data and predictive computational modeling

    NASA Astrophysics Data System (ADS)

    Koutsourelakis, P. S.; Zabaras, N.; Girolami, M.

    2016-09-01

    The motivation for this special issue stems from the symposium on "Big Data and Predictive Computational Modeling" that took place at the Institute for Advanced Study, Technical University of Munich, during May 18-21, 2015. With a mindset firmly grounded in computational discovery, but a polychromatic set of viewpoints, several leading scientists, from physics and chemistry, biology, engineering, applied mathematics, scientific computing, neuroscience, statistics and machine learning, engaged in discussions and exchanged ideas for four days. This special issue contains a subset of the presentations. Video and slides of all the presentations are available on the TUM-IAS website http://www.tum-ias.de/bigdata2015/.

  13. Deep Search for Satellites Around the Lucy Mission Targets

    NASA Astrophysics Data System (ADS)

    Noll, Keith

    2017-08-01

    By performing the first deep search for Trojan satellites with HST we will obtain unique constraints on satellite-forming processes in this population. We have selected the targets from NASA's Lucy mission because they represent a taxonomically and physically diverse set of targets that allow intercomparisons from a small survey. Also, by searching now to identify any orbiting material around the Lucy targets, it will be possible impact hardware decisions and plan for maximum scientific return from the mission. This search also is a necessary step to assure mission safety as the Lucy spacecraft will fly within 1000 km of the targets, well within the region where stable orbits can exist.

  14. Physical Aggression During Early Childhood: Trajectories and Predictors

    PubMed Central

    Tremblay, Richard E.; Nagin, Daniel S.; Séguin, Jean R.; Zoccolillo, Mark; Zelazo, Philip D.; Boivin, Michel; Pérusse, Daniel; Japel, Christa

    2012-01-01

    Objectives Physical aggression in children is a major public health problem. Not only is childhood physical aggression a precursor of the physical and mental health problems that will be visited on victims, but also aggressive children themselves are at higher risk of alcohol and drug abuse, accidents, violent crimes, depression, suicide attempts, spouse abuse, and neglectful and abusive parenting. Furthermore, violence commonly results in serious injuries to the perpetrators themselves. Although it is unusual for young children to harm seriously the targets of their physical aggression, studies of physical aggression during infancy indicate that by 17 months of age, the large majority of children are physically aggressive toward siblings, peers, and adults. This study aimed, first, to identify the trajectories of physical aggression during early childhood and, second, to identify antecedents of high levels of physical aggression early in life. Such antecedents could help to understand better the developmental origins of violence later in life and to identify targets for preventive interventions. Methods A random population sample of 572 families with a 5-month-old newborn was recruited. Assessments of physical aggression frequency were obtained from mothers at 17, 30, and 42 months after birth. Using a semiparametric, mixture model, distinct clusters of physical aggression trajectories were identified. Multivariate logit regression analysis was then used to identify which family and child characteristics, before 5 months of age, predict individuals on a high-level physical aggression trajectory from 17 to 42 months after birth. Results Three trajectories of physical aggression were identified. The first was composed of children who displayed little or no physical aggression. These individuals were estimated to account for ~28% of the sample. The largest group, estimated at ~58% of the sample, followed a rising trajectory of modest aggression. Finally, a group

  15. Target Fabrication Technology and New Functional Materials for Laser Fusion and Laser-Plasma Experiment

    NASA Astrophysics Data System (ADS)

    Nagai, Keiji; Norimatsu, Takayoshi; Izawa, Yasukazu

    Target fabrication technique is a key issue of laser fusion. We present a comprehensive, up-to-data compilation of laser fusion target fabrication and relating new materials. To achieve highly efficient laser implosion, organic and inorganic highly spherical millimeter-sized capsules and cryogenic hydrogen layers inside should be uniform in diameter and thickness within sub-micrometer ˜ nanometer error. Porous structured targets and molecular cluster targets are required for laser-plasma experiments and applications. Various technologies and new materials concerning above purposes are summarized including fast-ignition targets, equation-of-state measurement targets, high energy ion generation targets, etc.

  16. Listening for Prescriptions: A National Consultation on Pharmaceutical Policy Issues

    PubMed Central

    Morgan, Steve; Cunningham, Colleen M.

    2010-01-01

    Objectives and Methods: Pharmaceutical policy is an increasingly costly, essential and challenging component of health system management. We sought to identify priority pharmaceutical policy issues in Canada and to translate them into research priorities using key informant interviews, stakeholder surveys and a deliberative workshop. Results: We found consensus on overarching policy goals: to provide all Canadians with equitable and sustainable access to necessary medicines. We also found widespread frustration that many key pharmaceutical policy issues in Canada — including improving prescription drug financing and pricing — have been persistent challenges owing to a lack of policy coordination. The coverage of extraordinarily costly medicines for serious conditions was identified as a rapidly emerging policy issue. Conclusion: Targeted research and knowledge translation activities can help address key policy issues and, importantly, challenges of policy coordination in Canada and thereby reduce inequity and inefficiency in policy approaches and outcomes. PMID:22043223

  17. Editorial of the PCCP themed issue on "Solvation Science".

    PubMed

    Morgenstern, Karina; Marx, Dominik; Havenith, Martina; Muhler, Martin

    2015-04-07

    The present special issue presents exciting experimental and theoretical results in the topic of "Solvation Science", a topic that emerges from physical, theoretical, and industrial chemistry, and is also of interest to a multitude of neighboring fields, such as inorganic and organic chemistry, biochemistry, physics and engineering. We hope that the articles will be highly useful for researchers who would like to enter this newly emerging area, and that it is a valuable source for the nucleation of new ideas and collaborations to better understand the active role of the solvent in reactions.

  18. Physics Literacy for All Students

    NASA Astrophysics Data System (ADS)

    Hobson, Art

    2010-03-01

    Physics teachers must broaden their focus from physics for scientists to physics for all. The reason, as the American Association for the Advancement of Science puts it, is: ``Without a scientifically literate population, the outlook for a better world is not promising.'' Physics for all (including the first course for scientists) should be conceptual, not technical. It should describe the universe as we understand it today, including special and general relativity, quantum physics, modern cosmology, the standard model, and quantum fields. Many science writers have shown this is possible. It should include physics-related social topics such as global warming and nuclear weapons, because citizens need to vote on these issues. Above all, it should emphasize the scientific process and the difference between science and nonsense. Science is based not on beliefs but rather on evidence and reason. We should constantly ask ``How do we know?'' and ``What is the evidence?''

  19. Teachers' approaches to teaching physics

    NASA Astrophysics Data System (ADS)

    2012-12-01

    Benjamin Franklin said, "Tell me, and I forget. Teach me, and I remember. Involve me, and I learn." He would not be surprised to learn that research in physics pedagogy has consistently shown that the traditional lecture is the least effective teaching method for teaching physics. We asked high school physics teachers which teaching activities they used in their classrooms. While almost all teachers still lecture sometimes, two-thirds use something other than lecture most of the time. The five most often-used activities are shown in the table below. In the January issue, we will look at the 2013 Nationwide Survey of High School Physics teachers. Susan White is Research Manager in the Statistical Research Center at the American Institute of Physics; she directs the Nationwide Survey of High School Physics Teachers. If you have any questions, please contact Susan at swhite@aip.org.

  20. Equity and Difference in Physical Education, Youth Sport and Health: A Narrative Approach. Routledge Studies in Physical Education and Youth Sport

    ERIC Educational Resources Information Center

    Dowling, Fiona, Ed.; Fitzgerald, Hayley, Ed.; Flintoff, Anne, Ed.

    2012-01-01

    Issues of equity remain an essential theme throughout the study and practice of physical education (PE), youth sport and health. This important new book confronts and illuminates issues of equity and difference through the innovative use of narrative method, telling stories of difference that enable students, academics and professionals alike to…

  1. Message From the Editor for Contributions to the 2016 Real Time Conference Issue of TNS

    NASA Astrophysics Data System (ADS)

    Schmeling, Sascha Marc

    2017-06-01

    This issue of the IEEE Transactions on Nuclear Science (TNS) is devoted to the 20th IEEE-NPSS Real Time Conference (RT2016) on Computing Applications in Nuclear and Plasma Sciences held in Padua, Italy, in June 2016. A total of 90 papers presented at the conference were submitted for possible publication in TNS. This conference issue presents 46 papers, which have been accepted so far after a thorough peer review process. These contributions come from a very broad range of fields of application, including Astrophysics, Medical Imaging, Nuclear and Plasma Physics, Particle Accelerators, and Particle Physics Experiments. Several papers were close to being accepted but did not make it into this special issue. They will be considered for further publication.

  2. Lifting wavelet method of target detection

    NASA Astrophysics Data System (ADS)

    Han, Jun; Zhang, Chi; Jiang, Xu; Wang, Fang; Zhang, Jin

    2009-11-01

    Image target recognition plays a very important role in the areas of scientific exploration, aeronautics and space-to-ground observation, photography and topographic mapping. Complex environment of the image noise, fuzzy, all kinds of interference has always been to affect the stability of recognition algorithm. In this paper, the existence of target detection in real-time, accuracy problems, as well as anti-interference ability, using lifting wavelet image target detection methods. First of all, the use of histogram equalization, the goal difference method to obtain the region, on the basis of adaptive threshold and mathematical morphology operations to deal with the elimination of the background error. Secondly, the use of multi-channel wavelet filter wavelet transform of the original image de-noising and enhancement, to overcome the general algorithm of the noise caused by the sensitive issue of reducing the rate of miscarriage of justice will be the multi-resolution characteristics of wavelet and promotion of the framework can be designed directly in the benefits of space-time region used in target detection, feature extraction of targets. The experimental results show that the design of lifting wavelet has solved the movement of the target due to the complexity of the context of the difficulties caused by testing, which can effectively suppress noise, and improve the efficiency and speed of detection.

  3. Targeting children of substance-using parents with the community-based group intervention TRAMPOLINE: A randomised controlled trial - design, evaluation, recruitment issues

    PubMed Central

    2012-01-01

    Background Children of substance-abusing parents are at risk for developing psychosocial development problems. In Germany it is estimated that approx. 2.65 million children are affected by parental substance abuse or dependence. Only ten percent of them receive treatment when parents are treated. To date, no evaluated programme for children from substance-affected families exists in Germany. The study described in this protocol is designed to test the effectiveness of the group programme TRAMPOLINE for children aged 8-12 years with at least one substance-abusing or -dependent caregiver. The intervention is specifically geared to issues and needs of children from substance-affected families. Methods/Design The effectiveness of the manualised nine-session group programme TRAMPOLINE is tested among N = 218 children from substance-affected families in a multicentre randomised controlled trial. Outpatient counselling facilities across the nation from different settings (rural/urban, Northern/Southern/Eastern/Western regions of the country) will deliver the interventions, as they hold the primary access to the target group in Germany. The control condition is a group programme with the same duration that is not addiction-specific. We expect that participants in the intervention condition will show a significant improvement in the use of adaptive coping strategies (in general and within the family) compared to the control condition as a direct result of the intervention. Data is collected shortly before and after as well as six months after the intervention. Discussion In Germany, the study presented here is the first to develop and evaluate a programme for children of substance-abusing parents. Limitations and strengths are discussed with a special focus on recruitment challenges as they appear to be the most potent threat to feasibility in the difficult-to-access target group at hand (Trial registration: ISRCTN81470784). PMID:22439919

  4. Targeting children of substance-using parents with the community-based group intervention TRAMPOLINE: a randomised controlled trial--design, evaluation, recruitment issues.

    PubMed

    Bröning, Sonja; Wiedow, Annika; Wartberg, Lutz; Ruths, Sylvia; Haevelmann, Andrea; Kindermann, Sally-Sophie; Moesgen, Diana; Schaunig-Busch, Ines; Klein, Michael; Thomasius, Rainer

    2012-03-22

    Children of substance-abusing parents are at risk for developing psychosocial development problems. In Germany it is estimated that approx. 2.65 million children are affected by parental substance abuse or dependence. Only ten percent of them receive treatment when parents are treated. To date, no evaluated programme for children from substance-affected families exists in Germany. The study described in this protocol is designed to test the effectiveness of the group programme TRAMPOLINE for children aged 8-12 years with at least one substance-abusing or -dependent caregiver. The intervention is specifically geared to issues and needs of children from substance-affected families. The effectiveness of the manualised nine-session group programme TRAMPOLINE is tested among N = 218 children from substance-affected families in a multicentre randomised controlled trial. Outpatient counselling facilities across the nation from different settings (rural/urban, Northern/Southern/Eastern/Western regions of the country) will deliver the interventions, as they hold the primary access to the target group in Germany. The control condition is a group programme with the same duration that is not addiction-specific. We expect that participants in the intervention condition will show a significant improvement in the use of adaptive coping strategies (in general and within the family) compared to the control condition as a direct result of the intervention. Data is collected shortly before and after as well as six months after the intervention. In Germany, the study presented here is the first to develop and evaluate a programme for children of substance-abusing parents. Limitations and strengths are discussed with a special focus on recruitment challenges as they appear to be the most potent threat to feasibility in the difficult-to-access target group at hand (Trial registration: ISRCTN81470784).

  5. Drug Target Protein-Protein Interaction Networks: A Systematic Perspective

    PubMed Central

    2017-01-01

    The identification and validation of drug targets are crucial in biomedical research and many studies have been conducted on analyzing drug target features for getting a better understanding on principles of their mechanisms. But most of them are based on either strong biological hypotheses or the chemical and physical properties of those targets separately. In this paper, we investigated three main ways to understand the functional biomolecules based on the topological features of drug targets. There are no significant differences between targets and common proteins in the protein-protein interactions network, indicating the drug targets are neither hub proteins which are dominant nor the bridge proteins. According to some special topological structures of the drug targets, there are significant differences between known targets and other proteins. Furthermore, the drug targets mainly belong to three typical communities based on their modularity. These topological features are helpful to understand how the drug targets work in the PPI network. Particularly, it is an alternative way to predict potential targets or extract nontargets to test a new drug target efficiently and economically. By this way, a drug target's homologue set containing 102 potential target proteins is predicted in the paper. PMID:28691014

  6. Proceedings of the twelfth target fabrication specialists` meeting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1999-04-01

    Research in fabrication for inertial confinement fusion (ICF) comprises at least three broad categories: targets for high energy density physics on existing drivers, ignition capsule fabrication, and cryogenic fuel layer formation. The latter two are being pursued primarily for the National Ignition Facility (NIF). Scientists from over 14 laboratories, universities, and businesses contributed over 100 papers on all aspects of ICF target fabrication. The NIF is well along in construction and photos of poured concrete and exposed steel added to the technical excitement. It was clear from the meeting that there has been significant progress toward the fabrication of anmore » ignition target for NIF and that new techniques are resulting in higher quality targets for high energy density research.« less

  7. Current issues in ALS epidemiology: Variation of ALS occurrence between populations and physical activity as a risk factor.

    PubMed

    Luna, J; Logroscino, G; Couratier, P; Marin, B

    2017-05-01

    Amyotrophic lateral sclerosis (ALS) is a rare neurodegenerative disease with a fatal outcome. This review aims to report key epidemiological features of ALS in relation to the hypothesis of variation between populations, to summarize environmental hypothesis and to highlight current issues that deserve much considerations. Epidemiological ALS studies have shown a variation of incidence, mortality and prevalence between geographical areas and different populations. These data could support the notion that genetic factors, especially populations' ancestries, along with environmental and lifestyle factors, play a significant role in the occurrence of the disease. To date, there is no strong evidence to confirm an association between a particular environmental factor and ALS. Physical activity (PA) has been extensively evaluated. Recent studies support with the best evidence level that PA in general population is not a risk factor for ALS. However, further research is needed to clarify the association of PA in some occupations and some athletic activities. Epidemiological research based on multicenter international collaboration is essential to provide new data on ALS especially in some regions of the world that are to date poorly represented in the ALS literature. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  8. PREFACE: 15th Russian Youth Conference on Physics and Astronomy (PhysicA.SPb)

    NASA Astrophysics Data System (ADS)

    Sokolovskii, Grigorii; Averkiev, Nikita

    2013-08-01

    The fifteenth Russian Youth Conference on Physics and Astronomy PhysicA.SPb was held 23-24 October 2012 in Saint-Petersburg, Russia. The Conference continues the tradition of Saint-Petersburg Seminars on Physics and Astronomy originating from the mid-90s. The main feature of PhysicA.SPb since then, remains the combination of both scientific and educational quality of the contributions delivered to the young audience. This feature makes it possible to combine the whole spectrum of modern Physics and Astronomy within one conference. PhysicA.SPb 2012 has brought together more than 150 students, young scientists and their professors from many universities and research institutes across Russia, as well as from Belarus, Ukraine, Finland, France and the United Kingdom. Oral and poster presentations were combined into a few well-defined sections among which one should name Astronomy and Astrophysics, Physics of semiconductors, Physics of solid state, Physics and technology of the alternative energetics, Nanostructured and thin-film materials, THz and UHF materials and devices, and Physics of the quantum-sized structures. This issue of the Journal of Physics: Conference Series presents the extended contributions from participants of PhysicA.SPb 2012 that were peer-reviewed by expert referees through processes administered by the Presiders of the Organising and Programme Committees to the best professional and scientific standards. Grigorii S. Sokolovskii and Nikita S. Averkiev Editors

  9. Evolution of regulatory targets for drinking water quality.

    PubMed

    Sinclair, Martha; O'Toole, Joanne; Gibney, Katherine; Leder, Karin

    2015-06-01

    The last century has been marked by major advances in the understanding of microbial disease risks from water supplies and significant changes in expectations of drinking water safety. The focus of drinking water quality regulation has moved progressively from simple prevention of detectable waterborne outbreaks towards adoption of health-based targets that aim to reduce infection and disease to a level well below detection limits at the community level. This review outlines the changes in understanding of community disease and waterborne risks that prompted development of these targets, and also describes their underlying assumptions and current context. Issues regarding the appropriateness of selected target values, and how continuing changes in knowledge and practice may influence their evolution, are also discussed.

  10. ACHP | News | ACHP Issue Spotlight: Transmission Lines in the West

    Science.gov Websites

    include issues related to historic preservation law, ethics, Freedom of Information Act, and related to Preservation 50 and the Preserve America program for social media, presentations, and the Web ACHP's social media efforts and targeted stories by themes. Assist with activities relating to the ACHP

  11. What Should Space Be Used For? Physical and Political Guidelines

    NASA Astrophysics Data System (ADS)

    Grego, Laura

    2005-04-01

    Space has long been important to the commercial, civil scientific, and military sectors, serving essential missions like communications, environmental monitoring and astronomical research, early warning of missile attack, and precision navigation. However, rhetoric, official planning documents, and funded military research programs show that the current administration has a vision for space that significantly departs from long-held norms. This new vision includes four additional missions for satellites: 1) ballistic missile defense, 2) attacking targets on the ground 3) protecting other satellites, and 4) denying other users the ability to operate in space. Such a dramatic change deserves a thorough vetting. The discussion can be organized into three main types of issues: The first are international and strategic issues, such as how space weaponization may affect national and international security and stability; and, in space, what are the roles of weapons versus treaties and cooperation? Second: how useful would space actually be for these four proposed military missions? The laws of physics and the current state of technology will strongly limit what orbiting craft can do. And third: how may these new uses of space affect other current and future users of space? And what are the proper guidelines for the equitable use and longterm stewardship of space?

  12. NON-TARGET AND ECOSYSTEM IMPACTS FROM GENETICALLY MODIFIED CROPS CONTAINING PLANT INCORPORATED PROTECTANTS (PIPS)

    EPA Science Inventory

    The risk of unintended and unexpected adverse impacts on non-target organisms and ecosystems is a key issue in environmental risk assessment of PIP crop plants. While there has been considerable examination of the effects of insect resistant crops on certain non-target organisms...

  13. Design of the LBNF Beamline Target Station

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tariq, S.; Ammigan, K.; Anderson, K.

    2016-10-01

    The Long Baseline Neutrino Facility (LBNF) project will build a beamline located at Fermilab to create and aim an intense neutrino beam of appropriate energy range toward the DUNE detectors at the SURF facility in Lead, South Dakota. Neutrino production starts in the Target Station, which consists of a solid target, magnetic focusing horns, and the associated sub-systems and shielding infrastructure. Protons hit the target producing mesons which are then focused by the horns into a helium-filled decay pipe where they decay into muons and neutrinos. The target and horns are encased in actively cooled steel and concrete shielding inmore » a chamber called the target chase. The reference design chase is filled with air, but nitrogen and helium are being evaluated as alternatives. A replaceable beam window separates the decay pipe from the target chase. The facility is designed for initial operation at 1.2 MW, with the ability to upgrade to 2.4 MW, and is taking advantage of the experience gained by operating Fermilab’s NuMI facility. We discuss here the design status, associated challenges, and ongoing R&D and physics-driven component optimization of the Target Station.« less

  14. Drug targeting of oncogenic pathways in melanoma.

    PubMed

    Fecher, Leslie A; Amaravadi, Ravi K; Schuchter, Lynn M; Flaherty, Keith T

    2009-06-01

    Melanoma continues to be one of the most aggressive and morbid malignancies once metastatic. Overall survival for advanced unresectable melanoma has not changed over the past several decades. However, the presence of some long-term survivors of metastatic melanoma highlights the heterogeneity of this disease and the potential for improved outcomes. Current research is uncovering the molecular and genetic scaffolding of normal and aberrant cell function. The known oncogenic pathways in melanoma and the attempts to develop therapy for them are discussed. The targeting of certain cellular processes, downstream of the common genetic alterations, for which the issues of target and drug validation are somewhat distinct, are also highlighted.

  15. Preface: Twenty-First Target Fabrication Specialists Meeting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nikroo, Abbas; Czechowicz, Don

    The Twenty First Target Fabrication Meeting held in Las Vegas, Nevada, from June xx-yy 2015, was attended by more than 100 scientists, engineers, and technicians from the United States, the United Kingdom, France, and Japan, bringing together international experts on the design, development, and fabrication of inertial confinement fusion (ICF) and high-energy-density (HED) experimental targets fielded on laser and pulsed-power facilities around the world. We were delighted to have such exceptional international representation. The program included 4 invited papers, 53 contributed papers, and 55 posters. A selection of these is presented in this dedicated issue of Fusion Science and Technologymore » (FST).« less

  16. Preface: Twenty-First Target Fabrication Specialists Meeting

    DOE PAGES

    Nikroo, Abbas; Czechowicz, Don

    2017-04-21

    The Twenty First Target Fabrication Meeting held in Las Vegas, Nevada, from June xx-yy 2015, was attended by more than 100 scientists, engineers, and technicians from the United States, the United Kingdom, France, and Japan, bringing together international experts on the design, development, and fabrication of inertial confinement fusion (ICF) and high-energy-density (HED) experimental targets fielded on laser and pulsed-power facilities around the world. We were delighted to have such exceptional international representation. The program included 4 invited papers, 53 contributed papers, and 55 posters. A selection of these is presented in this dedicated issue of Fusion Science and Technologymore » (FST).« less

  17. Exploring issues of participation among adolescents with cerebral palsy: what's important to them?

    PubMed

    Livingston, Michael H; Stewart, Debra; Rosenbaum, Peter L; Russell, Dianne J

    2011-08-01

    The purpose of this cross-sectional study was to determine what participation issues are important to adolescents with cerebral palsy (CP). Two hundred and three adolescents with CP (mean age 16.0 ± 1.8 years) were assessed using the Canadian Occupational Performance Measure (COPM). This was done through semistructured interviews by trained physical and occupational therapists. Adolescents responded either directly (n = 144) or through a parent or a caregiver (n = 59) if they were unable to communicate. Issues were extracted from completed questionnaires and coded under three COPM categories (self-care, productivity, and leisure) and 16 subcategories. There was no association between the total number of issues identified and gender (p = .99), age (p = .88), type of respondent (adolescents versus parent) (p = .27), Gross Motor Function Classification System (GMFCS) level (p = .93), or 66-item Gross Motor Function Measure (GMFM-66) score (p = .45). The issues identified most frequently were related to active leisure (identified by 57% of participants), mobility (55%), school (48%), and socialization (44%). Interventions aimed at improving participation among adolescents with physical disabilities, such as CP, should be directed towards these four key areas. Health care professionals should also recognize and consider the interaction of person and environment when addressing issues related to participation.

  18. Alternative divertor target concepts for next step fusion devices

    NASA Astrophysics Data System (ADS)

    Mazul, I. V.

    2016-12-01

    The operational conditions of a divertor target in the next steps of fusion devices are more severe in comparison with ITER. The current divertor designs and technologies have a limited application concerning these conditions, and so new design concepts/technologies are required. The main reasons which practically prevent the use of the traditional motionless solid divertor target are analyzed. We describe several alternative divertor target concepts in this paper. The comparative analysis of these concepts (including the advantages and the drawbacks) is made and the prospects for their practical implementation are prioritized. The concept of the swept divertor target with a liquid metal interlayer between the moving armour and motionless heat-sink is presented in more detail. The critical issues of this design are listed and outlined, and the possible experiments are presented.

  19. Will nanotechnology influence targeted cancer therapy?

    PubMed Central

    Grimm, Jan; Scheinberg, David A.

    2011-01-01

    The rapid development of techniques that enable synthesis (and manipulation) of matter on the nanometer scale, as well as the development of new nano-materials, will play a large role in disease diagnosis and treatment, specifically in targeted cancer therapy. Targeted nanocarriers are an intriguing means to selectively deliver high concentrations of cytotoxic agents or imaging labels directly to the cancer site. Often solubility issues and an unfavorable biodistribution can result in a suboptimal response of novel agents even though they are very potent. New nanoparticulate formulations allow simultaneous imaging and therapy (“theranostics”), which can provide a realistic means for the clinical implementation of such otherwise suboptimal formulations. In this review we will not attempt to provide a complete overview of the rapidly enlarging field of nanotechnology in cancer; rather, we will present properties specific to nanoparticles, and examples of their uses, which demonstrate their importance for targeted cancer therapy. PMID:21356476

  20. Teaching physics to radiology residents.

    PubMed

    Hendee, William R

    2009-04-01

    The complexity of diagnostic imaging has expanded dramatically over the past two decades. Over the same period, the time and effort devoted to teaching physics (the science and technology of the discipline) have diminished. This paradox compromises the ability of future radiologists to master imaging technologies so that they are used in an efficient, safe, and cost-effective manner. This article addresses these issues. Efforts involving many professional organizations are under way to resolve the paradox of the expanding complexity of medical imaging contrasted with the declining emphasis on physics in radiology residency programs. These efforts should help to reestablish physics education as a core value in radiology residency programs.

  1. Critical Science Issues for Direct Drive Inertial Fusion Energy

    NASA Astrophysics Data System (ADS)

    Dahlburg, Jill P.; Gardner, John H.; Schmitt, Andrew J.; Obenschain, S. P.

    1998-09-01

    There are several topics that require resolution prior to the construction of an Inertial Fusion Energy [IFE] laboratory Engineering Test Facility [ETF]: a pellet that produces high gain; a pellet fabrication system that cost-effectively and rapidly manufactures these pellets; a sufficiently uniform and durable high repetition-rate laser pellet driver; a practical target injection system that provides accurate pellet aiming; and, a target chamber that will survive the debris and radiation of repeated high-gain pellet implosions. In this summary we describe the science issues and opportunities that are involved in the design of a successful high gain direct drive Inertial Confinement Fusion [ICF] pellet.

  2. An overview of the issues: physiological effects of bed rest and restricted physical activity

    NASA Technical Reports Server (NTRS)

    Convertino, V. A.; Bloomfield, S. A.; Greenleaf, J. E.

    1997-01-01

    Reduction of exercise capacity with confinement to bed rest is well recognized. Underlying physiological mechanisms include dramatic reductions in maximal stroke volume, cardiac output, and oxygen uptake. However, bed rest by itself does not appear to contribute to cardiac dysfunction. Increased muscle fatigue is associated with reduced muscle blood flow, red cell volume, capillarization and oxidative enzymes. Loss of muscle mass and bone density may be reflected by reduced muscle strength and higher risk for injury to bones and joints. The resultant deconditioning caused by bed rest can be independent of the primary disease and physically debilitating in patients who attempt to reambulate to normal active living and working. A challenge to clinicians and health care specialists has been the identification of appropriate and effective methods to restore physical capacity of patients during or after restricted physical activity associated with prolonged bed rest. The examination of physiological responses to bed rest deconditioning and exercise training in healthy subjects has provided significant information to develop effective rehabilitation treatments. The successful application of acute exercise to enhance orthostatic stability, daily endurance exercise to maintain aerobic capacity, or specific resistance exercises to maintain musculoskeletal integrity rather than the use of surgical, pharmacological, and other medical treatments for clinical conditions has been enhanced by investigation and understanding of underlying mechanisms that distinguish physical deconditioning from the disease. This symposium presents an overview of cardiovascular and musculoskeletal deconditioning associated with reduced physical work capacity following prolonged bed rest and exercise training regimens that have proven successful in ameliorating or reversing these adverse effects.

  3. The issue of gauge choice in the Landau problem and the physics of canonical and mechanical orbital angular momenta

    NASA Astrophysics Data System (ADS)

    Wakamatsu, M.; Kitadono, Y.; Zhang, P.-M.

    2018-05-01

    One intriguing issue in the nucleon spin decomposition problem is the existence of two types of decompositions, which are representably characterized by two different orbital angular momenta (OAMs) of quarks. The one is the mechanical OAM, while the other is the so-called gauge-invariant canonical (g.i.c.) OAM, the concept of which was introduced by Chen et al. An especially delicate quantity is the g.i.c. OAM, which must be distinguished from the ordinary (gauge-variant) canonical OAM. We find that, owing to its analytically solvable nature, the famous Landau problem offers an ideal tool to understand the difference and the physical meaning of the above three OAMs, i.e. the standard canonical OAM, g.i.c. OAM, and the mechanical OAM. We analyze these three OAMs in two different formulations of the Landau problem, first in the standard (gauge-fixed) formulation and second in the gauge-invariant (but path-dependent) formulation of DeWitt. Especially interesting is the latter formalism. It is shown that the choice of path has an intimate connection with the choice of gauge, but they are not necessarily equivalent. Then, we answer the question about what is the consequence of a particular choice of path in DeWitt's formalism. This analysis also clarifies the implication of the gauge symmetry hidden in the concept of g.i.c. OAM. Finally, we show that the finding above offers a clear understanding about the uniqueness or non-uniqueness problem of the nucleon spin decomposition, which arises from the arbitrariness in the definition of the so-called physical component of the gauge field.

  4. Contemporary Issues of Social Justice: A Focus on Race and Physical Education in the United States

    ERIC Educational Resources Information Center

    Harrison, Louis; Clark, Langston

    2016-01-01

    Ongoing events in the United States show the continual need to address issues of social justice in every social context. Of particular note in this article, the contemporary national focus on race has thrust social justice issues into the forefront of the country's conscious. Although legal segregation has ran its course, schools and many…

  5. NDCX-II target experiments and simulations

    DOE PAGES

    Barnard, J. J.; More, R. M.; Terry, M.; ...

    2013-06-13

    The ion accelerator NDCX-II is undergoing commissioning at Lawrence Berkeley National Laboratory (LBNL). Its principal mission is to explore ion-driven High Energy Density Physics (HEDP) relevant to Inertial Fusion Energy (IFE) especially in the Warm Dense Matter (WDM) regime. We have carried out hydrodynamic simulations of beam-heated targets for parameters expected for the initial configuration of NDCX-II. For metal foils of order one micron thick (thin targets), the beam is predicted to heat the target in a timescale comparable to the hydrodynamic expansion time for experiments that infer material properties from measurements of the resulting rarefaction wave. We have alsomore » carried out hydrodynamic simulations of beam heating of metallic foam targets several tens of microns thick (thick targets) in which the ion range is shorter than the areal density of the material. In this case shock waves will form and we derive simple scaling laws for the efficiency of conversion of ion energy into kinetic energy of fluid flow. Geometries with a tamping layer may also be used to study the merging of a tamper shock with the end-of-range shock. As a result, this process can occur in tamped, direct drive IFE targets.« less

  6. Recasting particle physics by entangling physics, history and philosophy

    NASA Astrophysics Data System (ADS)

    Bertozzi, Eugenio; Levrini, Olivia

    2016-05-01

    -1The paper presents the design process we followed to recast particle physics so as to make it conceptually relevant for secondary school students. In this design process, the concept of symmetry was assumed as core-idea because of its structural and foundational role in particle physics, its crosscutting character and its epistemological and philosophical value. The first draft of the materials was tested in a pilot-study which involved 19 students of a regular class (grade 13) of an Italian school. The data analysis showed that the students were in their "regime of competence" for grasping subtle nuances of the materials and for providing important hints for revising them. In particular, students' reactions brought into light the need of clarifying the "foundational" character that symmetry attained in twentieth-century physics. The delicate step of re-thinking the materials required the researchers to articulate the complex relationship between researches on physics teaching, history and philosophy of physics. This analytic phase resulted in a version of the materials which implies the students to be guided to grasp the meaning of symmetry as normative principle in twentieth-century physics, throughout the exploration of the different meanings assumed by symmetry over time. The whole process led also to the production of an essential, on-line version, of the materials targeted to a wider audience.

  7. Introduction to the Special Issue on Climate Ethics: Uncertainty, Values and Policy.

    PubMed

    Roeser, Sabine

    2017-10-01

    Climate change is a pressing phenomenon with huge potential ethical, legal and social policy implications. Climate change gives rise to intricate moral and policy issues as it involves contested science, uncertainty and risk. In order to come to scientifically and morally justified, as well as feasible, policies, targeting climate change requires an interdisciplinary approach. This special issue will identify the main challenges that climate change poses from social, economic, methodological and ethical perspectives by focusing on the complex interrelations between uncertainty, values and policy in this context. This special issue brings together scholars from economics, social sciences and philosophy in order to address these challenges.

  8. An Empathetic Approach to Physical Education Teacher Education

    ERIC Educational Resources Information Center

    Monahan, Tony

    2010-01-01

    The current crisis in societal obesity and other inactivity-related chronic health disorders has become a widespread concern in the United States. Physical Education (PE) with its propensity for physical activity has the potential to provide solutions to many chronic health issues. However, a large body of literature suggests that generations of…

  9. Losing Touch--Teachers' Self-Regulation in Physical Education

    ERIC Educational Resources Information Center

    Öhman, Marie

    2017-01-01

    The question of physical interaction is especially relevant in school physical education, where a lot of the teaching and activities are based on body movements. However, the issue of "touching" has been questioned in recent years. This paper takes its starting point in the discourse of child protection and the growing anxiety around…

  10. Bush Physics for the 21st Century, A Distance Delivery Physics Course Targeting Students in Rural Alaska and Across the North

    NASA Astrophysics Data System (ADS)

    Solie, D. J.; Spencer, V. K.

    2010-12-01

    Bush Physics for the 21st Century brings physics that is engaging to modern youth, and mathematically rigorous, to high school and college students in the remote and often road-less villages of Alaska where the opportunity to take a physics course has been nearly nonexistent. The primary goal of the course is to prepare rural (predominantly Alaska Native) students for success in university science and engineering degree programs and ultimately STEM careers. The course is delivered via video conference and web based electronic blackboard tailored to the needs of remote students. Kinetic, practical and culturally relevant place-based examples from traditional and modern northern life are used to engage students, and a rigorous and mathematical focus is stressed to strengthen problem solving skills. Simple hands-on-lab experiment kits are shipped to the students. In addition students conduct a Collaborative Research Experiment where they coordinate times of sun angle measurements with teams in other villages to determine their latitude and longitude as well as an estimate of the circumference of the earth. Connecting abstract mathematical symbols and equations to real physical objects and problems is one of the most difficult things to master in physics. We introduce Inuktitut symbols to complement the traditional Greek symbols in equations to strengthen the visual/conceptual connection with symbol and encourage an indigenous connection to the physical concepts. Results and observations from the first three pilot semesters (spring 2008, 2009 and 2010) will be presented.

  11. Multimode electromagnetic target discriminator: preliminary data results

    NASA Astrophysics Data System (ADS)

    Black, Christopher J.; McMichael, Ian T.; Nelson, Carl V.

    2004-09-01

    This paper describes the Multi-mode Electromagnetic Target Discriminator (METD) sensor and presents preliminary results from recent field experiments. The METD sensor was developed for the US Army RDECOM NVESD by The Johns Hopkins University Applied Physics Laboratory. The METD, based on the technology of the previously developed Electromagnetic Target Discriminator (ETD), is a spatial scanning electromagnetic induction (EMI) sensor that uses both the time-domain (TD) and the frequency-domain (FD) for target detection and classification. Data is collected with a custom data acquisition system and wirelessly transmitted to a base computer. We show that the METD has a high signal-to-noise ratio (SNR), the ability to detect voids created by plastic anti-tank (AT) mines, and is practical for near real-time data processing.

  12. Trauma is a public health issue.

    PubMed

    Magruder, Kathryn M; McLaughlin, Katie A; Elmore Borbon, Diane L

    2017-01-01

    Exposure to trauma is pervasive in societies worldwide and is associated with substantial costs to the individual and society, making it a significant global public health concern. We present evidence for trauma as a public health issue by highlighting the role of characteristics operating at multiple levels of influence - individual, relationship, community, and society - as explanatory factors in both the occurrence of trauma and its sequelae. Within the context of this multi-level framework, we highlight targets for prevention of trauma and its downstream consequences and provide examples of where public health approaches to prevention have met with success. Finally, we describe the essential role of public health policies in addressing trauma as a global public health issue, including key challenges for global mental health and next steps for developing and implementing a trauma-informed public health policy agenda. A public health framework is critical for understanding risk and protective factors for trauma and its aftermath operating at multiple levels of influence and generating opportunities for prevention.

  13. Psychosocial Support Issues Affecting Older Patients: A Cross-sectional Paramedic Perspective.

    PubMed

    Ross, Linda; Jennings, Paul; Williams, Brett

    2017-01-01

    This research aimed to gain an understanding of the psychosocial support needs of older patients in the out-of-hospital setting from the perspective of paramedics. Specifically, we investigate if and how paramedics are able to meet the needs of older adults, and the barriers preventing them from achieving this. This study was a cross-sectional study utilizing a sequential design with both quantitative and qualitative methodologies. All participants agreed or strongly agreed that older patients have needs beyond the physical and that they would like to do more for older patients. Paramedics discussed that psychosocial support issues are rarely in isolation and straightforward but were often coupled with broader, longer term physical health and social support issues. They would like to be able to do more for patients but feel hamstrung by lack of time, resources, and know-how.

  14. Psychosocial Support Issues Affecting Older Patients: A Cross-sectional Paramedic Perspective

    PubMed Central

    Ross, Linda; Jennings, Paul; Williams, Brett

    2017-01-01

    This research aimed to gain an understanding of the psychosocial support needs of older patients in the out-of-hospital setting from the perspective of paramedics. Specifically, we investigate if and how paramedics are able to meet the needs of older adults, and the barriers preventing them from achieving this. This study was a cross-sectional study utilizing a sequential design with both quantitative and qualitative methodologies. All participants agreed or strongly agreed that older patients have needs beyond the physical and that they would like to do more for older patients. Paramedics discussed that psychosocial support issues are rarely in isolation and straightforward but were often coupled with broader, longer term physical health and social support issues. They would like to be able to do more for patients but feel hamstrung by lack of time, resources, and know-how. PMID:28965434

  15. Physical Activity and Body Mass Index

    PubMed Central

    Nelson, Candace C.; Wagner, Gregory R.; Caban-Martinez, Alberto J.; Buxton, Orfeu M.; Kenwood, Christopher T.; Sabbath, Erika L.; Hashimoto, Dean M.; Hopcia, Karen; Allen, Jennifer; Sorensen, Glorian

    2014-01-01

    Background The workplace is an important domain for adults, and many effective interventions targeting physical activity and weight reduction have been implemented in the workplace. However, the U.S. workforce is aging and few studies have examined the relationship of BMI, physical activity, and age as they relate to workplace characteristics. Purpose This paper reports on the distribution of physical activity and BMI by age in a population of hospital-based healthcare workers and investigates the relationships among workplace characteristics, physical activity, and BMI. Methods Data from a survey of patient care workers in two large academic hospitals in the Boston area were collected in late 2009 and analyzed in early 2013. Results In multivariate models, workers reporting greater decision latitude (OR=1.02; 95% CI=1.01, 1.03) and job flexibility (OR=1.05; 95% CI=1.01, 1.10) reported greater physical activity. Overweight and obesity increased with age (p<0.01), even after adjusting for workplace characteristics. Sleep deficiency (OR=1.56; 95% CI=1.15, 2.12) and workplace harassment (OR= 1.62; 95% CI=1.20, 2.18) were also associated with obesity. Conclusions These findings underscore the persistent impact of the work environment for workers of all ages. Based on these results, programs or policies aimed at improving the work environment, especially decision latitude, job flexibility and workplace harassment should be included in the design of worksite-based health promotion interventions targeting physical activity or obesity. PMID:24512930

  16. Cell targeting peptides as smart ligands for targeting of therapeutic or diagnostic agents: a systematic review.

    PubMed

    Mousavizadeh, Ali; Jabbari, Ali; Akrami, Mohammad; Bardania, Hassan

    2017-10-01

    Cell targeting peptides (CTP) are small peptides which have high affinity and specificity to a cell or tissue targets. They are typically identified by using phage display and chemical synthetic peptide library methods. CTPs have attracted considerable attention as a new class of ligands to delivery specifically therapeutic and diagnostic agents, because of the fact they have several advantages including easy synthesis, smaller physical sizes, lower immunogenicity and cytotoxicity and their simple and better conjugation to nano-carriers and therapeutic or diagnostic agents compared to conventional antibodies. In this systematic review, we will focus on the basic concepts concerning the use of cell-targeting peptides (CTPs), following the approaches of selecting them from peptide libraries. We discuss several developed strategies for cell-specific delivery of different cargos by CTPs, which are designed for drug delivery and diagnostic applications. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. On the history of the quantum. Introduction to the HQ4 special issue

    NASA Astrophysics Data System (ADS)

    Navarro, Jaume; Blum, Alexander; Lehner, Christoph

    2017-11-01

    Eight years ago, a special issue in this journal published a dozen papers with new studies on the history of quantum physics. That issue was an output of a conference in Utrecht one year earlier, the second in a series organized by the then existing large-scale project coordinated by the Max Planck Institute for the History of Science and the Fritz Haber Institute. Since then, that project has produced a number of publications, workshops and other academic outcomes, but more importantly, it triggered the consolidation of an international community of historians and philosophers of science producing novel work on the history of quantum physics. Five years after the third meeting, which took place in Berlin in 2010, many of the scholars from that group and some new ones met for four days in Donostia/San Sebastian for the HQ4 meeting. The time was ripe for new results to be shared and discussed, and this issue collects some of the papers presented at that gathering.

  18. Teach for Fitness: A Manual for Teaching Fitness Concepts in K-12 Physical Education. Current Issues.

    ERIC Educational Resources Information Center

    Priest, Laurie

    This book is designed to aid and to encourage physical education teachers to incorporate the concepts of physical fitness into the physical education curriculum. The activities are written in an outline format using the following headings: (1) concept; (2) activity and/or knowledge level; (3) location (school or home); (4) time needed; (5)…

  19. Albanian women in physics

    NASA Astrophysics Data System (ADS)

    Deda, Antoneta; Alushllari, Mirela; Mico, Silvana

    2015-12-01

    In this report, presented at the 5th IUPAP International Conference on Women in Physics, we describe the status of women physicists in Albania and offer some statistical data illustrating the present situation. Undergraduate physics enrollment by girls is high and stable, more women are receiving financial support for doctoral studies, women are well represented in recent academic promotions, and recently women scientists have been appointed to several leadership positions. However, both women and men are challenged by the overall low levels of funding for research and by issues of availability and affordability of child care.

  20. Fluorescent imaging of cancerous tissues for targeted surgery

    PubMed Central

    Bu, Lihong; Shen, Baozhong; Cheng, Zhen

    2014-01-01

    To maximize tumor excision and minimize collateral damage is the primary goal of cancer surgery. Emerging molecular imaging techniques have to “image-guided surgery” developing into “molecular imaging-guided surgery”, which is termed “targeted surgery” in this review. Consequently, the precision of surgery can be advanced from tissue-scale to molecule-scale, enabling “targeted surgery” to be a component of “targeted therapy”. Evidence from numerous experimental and clinical studies has demonstrated significant benefits of fluorescent imaging in targeted surgery with preoperative molecular diagnostic screening. Fluorescent imaging can help to improve intraoperative staging and enable more radical cytoreduction, detect obscure tumor lesions in special organs, highlight tumor margins, better map lymph node metastases, and identify important normal structures intraoperatively. Though limited tissue penetration of fluorescent imaging and tumor heterogeneity are two major hurdles for current targeted surgery, multimodality imaging and multiplex imaging may provide potential solutions to overcome these issues, respectively. Moreover, though many fluorescent imaging techniques and probes have been investigated, targeted surgery remains at a proof-of-principle stage. The impact of fluorescent imaging on cancer surgery will likely be realized through persistent interdisciplinary amalgamation of research in diverse fields. PMID:25064553

  1. Current issues and problems in welding science

    NASA Astrophysics Data System (ADS)

    David, S. A.; Debroy, T.

    1992-07-01

    Recent advances in welding science are examined with consideration given to the progress made in understanding physical processes of welding and in understanding weldment microstructure and properties and the correlation between microstructure and properties of the welds. Particular attention is given to the methods used for intelligent control and automation of welding. Also discussed are issues and problems that were brought to the surface by technological advances and interdisciplinary research on welding.

  2. Canada's Physical Activity Guide: examining print-based material for motivating physical activity in the workplace.

    PubMed

    Plotnikoff, Ronald C; Todosijczuk, Ivan; Johnson, Steven T; Karunamuni, Nandini

    2012-01-01

    The authors conducted a secondary analysis on 202 adults from the Physical Activity Workplace Study. The aim of this analysis was to examine demographic characteristics associated with reading Canada's Physical Activity Guide (CPAG), being motivated by the guide, and whether participants in the Physical Activity Workplace Study who read the CPAG increased their physical activity levels over 1 year. Results revealed that less than 50% of participants read the full version of CPAG, and less than 10% were motivated by it. The CPAG also appears to be more appealing to and effective for women than for men. Although the CPAG had some influence in increasing mild physical activity levels in a workplace sample, there was also a decrease in physical activity levels among some members of the group. Overall, the effectiveness of CPAG was not substantial, and the findings of this analysis could help guide future targeted intervention materials and programs.

  3. Introduction to special issue: Attention & Plasticity.

    PubMed

    Hopfinger, Joseph B

    2017-04-01

    Mechanisms of attention are a prime target for investigating the plasticity of the adult brain, as these core mechanisms act at the intersection of top-down and bottom-up processing, and the wide variety of methods used in attention research can be utilized to elucidate the mechanisms of plasticity. This special issue of Cognitive Neuroscience presents three new empirical papers and a discussion paper with peer commentaries. In the first article, Voelker, Sheese, and colleagues investigate the influence of genetic variation on the effectiveness of attention training. Della Libera and colleagues then present a study investigating how individual differences in personality traits affect the acquisition of reward-based attention biases. In the final empirical paper, Hopfinger and colleagues present a transcranial stimulation study investigating the influence of different oscillatory stimulations on the efficiency of attentional reorienting. Finally, Voelker, Piscopo, and colleagues present a discussion paper in which they suggest that successful training of attention is linked to changes in the underlying white matter. The papers in this special issue present a sampling of the range of issues and methodologies being brought to bear to further our understanding of the malleability of the mechanisms of attention and of the plasticity of the brain.

  4. Physics teachers' perspectives on factors that affect urban physics participation and accessibility

    NASA Astrophysics Data System (ADS)

    Kelly, Angela M.

    2013-06-01

    The accessibility of secondary physics in U.S. urban school districts is a complex issue. Many schools do not offer a physics option, and for those that do, access is often restricted by various school policies and priorities that do not promote physics participation for all. To analyze this problem in greater depth, I adopted a qualitative phenomenological methodology to explore urban physics teachers’ views on school- and district-based conditions that may marginalize traditionally underrepresented students. Teachers from three large urban districts shared concerns and suggestions regarding administrative commitment, student preparedness for physics, reform initiatives and testing mandates, promoting physics enrollments, and implementing high quality instruction. Data from interviews and focus groups provided contextual insights into ways in which physics study may be improved and encouraged for urban youth. Teachers believed expanding access could be facilitated with differentiated levels of physics, incorporating mathematical applications with multiple representations, educating students and counselors on the ramifications of choosing or not choosing elective sciences, well-designed grant-funded initiatives, and flexibility with prerequisites and science course sequencing. Teachers experienced frustration with standardized testing, lack of curricular autonomy, shifting administrative directives, and top-down reforms that did not incorporate their feedback in the decision-making processes. Data from this study revealed that physics teacher networks, often housed at local universities, have been a key resource for establishing supportive professional communities to share best practices that may influence school-based reforms that promote physics participation in urban schools.

  5. Having Both a Family and a Future in Physics

    NASA Astrophysics Data System (ADS)

    McNeil, Laurie

    1997-11-01

    This session, sponsored by the APS Committee on the Status of Women in Physics (CSWP), will consist of a panel discussion in which men and women who have faced the challenges of combining physics with family will share their experiences and discuss the issues they confront. The panelists will be asked to respond to questions such as: "Is this an issue that only affects women?" "Can you have tenure and children too?" "Daycare vs. homecare: does it harm the children?" "Can I bring my children to my workplace?" Audience participation in the disscussion will be encouraged.

  6. Current experiments in elementary particle physics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wohl, C.G.; Armstrong, F.E., Oyanagi, Y.; Dodder, D.C.

    1987-03-01

    This report contains summaries of 720 recent and current experiments in elementary particle physics (experiments that finished taking data before 1980 are excluded). Included are experiments at Brookhaven, CERN, CESR, DESY, Fermilab, Moscow Institute of Theoretical and Experimental Physics, Tokyo Institute of Nuclear Studies, KEK, LAMPF, Leningrad Nuclear Physics Institute, Saclay, Serpukhov, SIN, SLAC, and TRIUMF, and also experiments on proton decay. Instructions are given for searching online the computer database (maintained under the SLAC/SPIRES system) that contains the summaries. Properties of the fixed-target beams at most of the laboratories are summarized.

  7. The Seventh Annual National Conference of Black Physics Students

    NASA Technical Reports Server (NTRS)

    Crawley, Gerard M.

    1993-01-01

    The National Conference of Black Physics Students began in 1986 when several Black physics graduate students at MIT and Harvard decided to address the 'pipeline problem' of African Americans in physics by organizing a conference for Black physics undergraduates. The goals of the conference were: (1) to develop a network within the Black physics community, (2) to make Black students in physics, particularly at graduate level, aware of academic and professional opportunities and (3) to bring important issues and developments in the field to the attention of these students. We are pleased to announce the Seventh Annual National Conference of Black Physics Students held February 12 and 13, 1993 served the largest population of students so far. The largest conference previous to this one hosted 150 students. We registered and prepared for 240 students with 210 actually attenting. We received so many qualified abstracts for technical talks by students that instead of NCBPS's tradition of 3-4 student presentations, we ran 4 parallel sessions in different rooms with 4-5 presentations in each room. In response to comments from previous conferences, the program contained 3 workshop/discussion sessions. The topics for the interactive discussion workshops were: 'Getting Ready for Graduate School,' 'How to Succeed in Graduate School,' and 'Issues Facing Black Scientists.'

  8. Physics constraints on double-pulse LIA engineering

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ekdahl, Carl August Jr.

    2015-05-20

    The options for advanced-radiography double-pulse linear induction accelerators (LIA) under consideration naturally fall into three categories that differ by the number of cells required. Since the two major physics issues, beam breakup (BBU) and corkscrew, are also dependent on the number of cells, it may be useful for the decision process to review the engineering consequences of beam physics constraints for each class. The LIAs can be categorized three different ways, and this report compares the different categories based upon the physics of their beams.

  9. Requirements on a community-based intervention for stimulating physical activity in physically disabled people: a focus group study amongst experts.

    PubMed

    Krops, Leonie A; Hols, Doortje H J; Folkertsma, Nienke; Dijkstra, Pieter U; Geertzen, Jan H B; Dekker, Rienk

    2017-06-14

    To explore ideas experts, working in the field of physical activity for people with a disability, pose on a stimulating movement intervention for physically disabled people longer than one year post rehabilitation or not familiar with rehabilitation. Four semi-structured focus groups were conducted with experts (n = 28). Transcripts were analysed following thematic analysis, using the integrated physical activity for people with a disability and intervention mapping model. Experts expressed no need for a new intervention, but, instead, a need for adapting an existing intervention, and increased collaboration between organisations. Such an adapted intervention should aim to change participants and environmental attitude towards physical activity, and to increase visibility of potential activities. Several methods were mentioned, for instance individual coaching. Potential participants should be personally approached via various intermediates. The intervention owner and government are responsible for stimulating physical activity and should finance an intervention together with health insurances and the user. According to experts adapting an existing intervention, together with increased collaboration between organisations, will be effective in stimulating physical activity in the target population. This study provides requirements on an intervention to stimulate physical activity, and suggestions for the approach of the target population, finance, and responsibility. Implications for Rehabilitation There is no need for designing a new intervention, but need for adaptation of an existing intervention for stimulating physical activity in physically disabled people. An intervention to stimulate physical activity in physically disabled people should aim to change participants and environmental attitude towards physical activity, and to increase the visibility of potential activities. Methods for stimulating physical activity in physically disabled people could be

  10. Evolution of Magnetized Liner Inertial Fusion (MagLIF) Targets

    DOE PAGES

    Fooks, J. A.; Carlson, L. C.; Fitzsimmons, P.; ...

    2017-12-19

    Here, the magnetized liner inertial fusion (MagLIF) experimental campaign conducted at the University of Rochester’s Laboratory for Laser Energetics (LLE) has evolved significantly since its start in 2014. Scientific requirements and OMEGA EP system technology both have progressed, resulting in necessary and available updates to the target design. These include, but are not limited to: optimizing target dimensions and aspect ratios to maximize survival at desired pressures; coating target components to enhance physics diagnosis; precision-machining diagnostic windows along the axis of the target; improving fiducial placement reproducibility and reducing subsequent assembly time by 50%; and implementing gas-pressure transducers on themore » targets. In addition, target fabrication techniques have changed and improved, allowing for simpler target reproducibility and decreased assembly time. To date, eleven variations of targets have been fabricated, with successful target fielding ranging from 1 to 20atm internal pressure and a maximum survivability of 33atm.« less

  11. Evolution of Magnetized Liner Inertial Fusion (MagLIF) Targets

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fooks, J. A.; Carlson, L. C.; Fitzsimmons, P.

    Here, the magnetized liner inertial fusion (MagLIF) experimental campaign conducted at the University of Rochester’s Laboratory for Laser Energetics (LLE) has evolved significantly since its start in 2014. Scientific requirements and OMEGA EP system technology both have progressed, resulting in necessary and available updates to the target design. These include, but are not limited to: optimizing target dimensions and aspect ratios to maximize survival at desired pressures; coating target components to enhance physics diagnosis; precision-machining diagnostic windows along the axis of the target; improving fiducial placement reproducibility and reducing subsequent assembly time by 50%; and implementing gas-pressure transducers on themore » targets. In addition, target fabrication techniques have changed and improved, allowing for simpler target reproducibility and decreased assembly time. To date, eleven variations of targets have been fabricated, with successful target fielding ranging from 1 to 20atm internal pressure and a maximum survivability of 33atm.« less

  12. The relationship between actual motor competence and physical activity in children: mediating roles of perceived motor competence and health-related physical fitness.

    PubMed

    Khodaverdi, Zeinab; Bahram, Abbas; Stodden, David; Kazemnejad, Anoshirvan

    2016-08-01

    The purpose of this study was to investigate whether perceived motor competence and components of health-related physical fitness mediated the relationship between actual motor competence and physical activity in 8- to 9-year-old Iranian girls. A convenience sample of 352 girls (mean age = 8.7, SD = 0.3 years) participated in the study. Actual motor competence, perceived motor competence and children's physical activity were assessed using the Test of Gross Motor Development-2, the physical ability sub-scale of Marsh's Self-Description Questionnaire and Physical Activity Questionnaire for Older Children, respectively. Body mass index, the 600 yard run/walk, curl-ups, push-ups, and back-saver sit and reach tests assessed health-related physical fitness. Preacher & Hayes (2004) bootstrap method was used to assess the potential mediating effects of fitness and perceived competence on the direct relationship between actual motor competence and physical activity. Regression analyses revealed that aerobic fitness (b = .28, 95% CI = [.21, .39]), as the only fitness measure, and perceived competence (b = .16, 95% CI = [.12, .32]) were measures that mediated the relationship between actual motor competence and physical activity with the models. Development of strategies targeting motor skill acquisition, children's self-perceptions of competence and cardiorespiratory fitness should be targeted to promote girls' moderate-to-vigorous physical activity.

  13. Physical activity helps to control music performance anxiety.

    PubMed

    Rocha, Sérgio F; Marocolo, Moacir; Corrêa, Elisangela N V; Morato, Gledys S G; da Mota, Gustavo R

    2014-06-01

    We evaluated if regular physical activity could influence musical performance anxiety (MPA) in college music students. Levels of MPA, as measured with the Kenny MPA Inventory, and a survey about the physical activity habits were obtained from 87 students of music. The results showed that physically active musicians had lower MPA scores (p<0.05) than non-active ones, independent of gender. We conclude that there is an association between physical activity and minor MPA, and studies with a longitudinal design should be done to explore this important issue.

  14. Affordable housing and health: a health impact assessment on physical inspection frequency.

    PubMed

    Klein, Elizabeth G; Keller, Brittney; Hood, Nancy; Holtzen, Holly

    2015-01-01

    To characterize the prevalence of health-related housing quality exposure for the vulnerable populations that live in affordable housing. Retrospective cross-sectional study. Affordable housing properties in Ohio inspected between 2007 and 2011. Stratified random sample of physical inspection reports (n = 370), including a case study of properties receiving multiple inspections (n = 35). Health-related housing factors, including mold, fire hazard, and others. The majority of affordable housing property inspections (85.1%) included at least 1 health-related housing quality issue. The prevalence of specific health-related violations was varied, with appliance and plumbing issues being the most common, followed by fire, mold, and pest violations. Across funding agencies, the actual implementation of inspection protocols differed. The majority of physical inspections identified housing quality issues that have the potential to impact human health. If the frequency of physical inspections is reduced as a result of inspection alignment, the most health protective inspection protocol should be selected for funding agency inspections; a standardized physical inspection tool is recommended to improve the consistency of inspection findings between mandatory physical inspections in order to promote optimum tenant health.

  15. Material issues relating to high power spallation neutron sources

    NASA Astrophysics Data System (ADS)

    Futakawa, M.

    2015-02-01

    Innovative researches using neutrons are being performed at the Materials and Life Science Experimental Facility (MLF) at the Japan Proton Accelerator Research Complex (J-PARC), in which a mercury target system is installed for MW-class pulse spallation neutron sources. In order to produce neutrons by the spallation reaction, proton beams are injected into the mercury target. At the moment, when the intense proton beam hits the target, pressure waves are generated in mercury because of the abrupt heat deposition. The pressure waves interact with the target vessel, leading to negative pressure that may cause cavitation along the vessel wall, i.e. on the interface between liquid and solid metals. On the other hand, the structural materials are subjected to irradiation damage due to protons and neutrons, very high cycle fatigue damages and so-called "liquid metal embrittlement". That is, the structural materials must be said to be exposed to the extremely severe environments. In the paper, research and development relating to the material issues in the high power spallation neutron sources that has been performed so far at J-PARC is summarized.

  16. Polarized deuterium internal target at AmPS (NIKHEF)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Norum, Blaine; De Jager, Cornelis; Geurts, D.

    1997-08-01

    We describe the polarized deuterium target internal to the NIKHEF medium-energy electron storage ring. Tensor polarized deuterium was produced in an atomic beam source and injected into a storage cell target. A Breit-Rabi polarimeter was used to monitor the injected atomic beam intensity and polarization. An electrostatic ion-extraction system and a Wien filter were utilized to measure on-line the atomic fraction of the target gas in the storage cell. This device was supplemented with a tensor polarization analyzer using the neutron anisotropy of the 3H(d,n)sigma reaction at 60 keV. This method allows determining the density-averaged nuclear polarization of the targetmore » gas, independent of spatial and temporal variations. We address issues important for polarized hydrogen/deuterium internal targets, such as the effects of spin-exchange collisions and resonant transitions induced by the RF fields of the charged particle beam.« less

  17. Targeted gene insertion for molecular medicine.

    PubMed

    Voigt, Katrin; Izsvák, Zsuzsanna; Ivics, Zoltán

    2008-11-01

    Genomic insertion of a functional gene together with suitable transcriptional regulatory elements is often required for long-term therapeutical benefit in gene therapy for several genetic diseases. A variety of integrating vectors for gene delivery exist. Some of them exhibit random genomic integration, whereas others have integration preferences based on attributes of the targeted site, such as primary DNA sequence and physical structure of the DNA, or through tethering to certain DNA sequences by host-encoded cellular factors. Uncontrolled genomic insertion bears the risk of the transgene being silenced due to chromosomal position effects, and can lead to genotoxic effects due to mutagenesis of cellular genes. None of the vector systems currently used in either preclinical experiments or clinical trials displays sufficient preferences for target DNA sequences that would ensure appropriate and reliable expression of the transgene and simultaneously prevent hazardous side effects. We review in this paper the advantages and disadvantages of both viral and non-viral gene delivery technologies, discuss mechanisms of target site selection of integrating genetic elements (viruses and transposons), and suggest distinct molecular strategies for targeted gene delivery.

  18. Approaches to the identification of new nonhormonal targets for male contraception.

    PubMed

    Kopf, Gregory S

    2008-10-01

    Fertility control is a global health issue with major personal and societal impact. Although, currently, there are several different options for contraception, the technologies behind these are antiquated, and the options for male-based contraception (i.e., withdrawal, condom and vasectomy) are inadequate. The genomic, proteomic and bioinformatic revolutions have provided new tools and new targets for contraceptive development, and the results of such approaches have identified gene products that play critical roles in male reproduction, thus expanding the array of potential targets for novel and innovative male-based contraceptives. This article will review the types of targets being considered in the development of nonhormonal male contraceptives and the technologies used to identify and validate these targets.

  19. Statistical analysis of target acquisition sensor modeling experiments

    NASA Astrophysics Data System (ADS)

    Deaver, Dawne M.; Moyer, Steve

    2015-05-01

    The U.S. Army RDECOM CERDEC NVESD Modeling and Simulation Division is charged with the development and advancement of military target acquisition models to estimate expected soldier performance when using all types of imaging sensors. Two elements of sensor modeling are (1) laboratory-based psychophysical experiments used to measure task performance and calibrate the various models and (2) field-based experiments used to verify the model estimates for specific sensors. In both types of experiments, it is common practice to control or measure environmental, sensor, and target physical parameters in order to minimize uncertainty of the physics based modeling. Predicting the minimum number of test subjects required to calibrate or validate the model should be, but is not always, done during test planning. The objective of this analysis is to develop guidelines for test planners which recommend the number and types of test samples required to yield a statistically significant result.

  20. Physics division. Progress report for period ending September 30, 1996

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ball, S.J.

    1997-04-01

    This report covers the research and development activities of the Physics Division for the 1995 and 1996 fiscal years, beginning October 1, 1994, and ending September 30, 1996. The activities of the Division continue to be concentrated in the areas of experimental nuclear physics, experimental atomic physics, and theoretical nuclear and atomic physics. In addition, there are smaller programs in plasma diagnostics and data compilation and evaluation. During the period of this report, there has been considerable success in bringing the Holifield Radioactive Ion Beam Facility (HRIBF) into routine operation. The budgets of the nuclear physics portion of the Divisionmore » have increased each year in nearly all areas, and several new members have been added to the Division research and development staff. On August 30, 1996, the HRIBF successfully accelerated its first radioactive ion beams, {sup 69}As and {sup 70}As. Prior to this, the heart of the facility, the RIB injector system, was completed, including installation of a remote handling system for the target/ion source assembly. Target and ion source development is likely to be the technical key to success of the HRIBF. We have expanded our efforts in those development areas. Of special note is the development of highly permeable composite targets which have now been shown to allow release of difficult-to-produce radioactive ions such as {sup 17,18}F. A summary of the HRIBF work is provided in Chapter 1, along with supporting activities of the Joint Institute for Heavy Ion Research.« less