Sample records for tavan har basement

  1. Changes of glacier, glacier-fed rivers and lakes in Altai Tavan Bogd National Park, Western Mongolia, based on multispectral satellite data from 1990 to 2017

    NASA Astrophysics Data System (ADS)

    Batsaikhan, B.; Lkhamjav, O.; Batsaikhan, N.

    2017-12-01

    Impacts on glaciers and water resource management have been altering through climate changes in Mongolia territory characterized by dry and semi-arid climate with low precipitation. Melting glaciers are early indicators of climate change unlike the response of the forests which is slower and takes place over a long period of time. Mountain glaciers are important environmental components of local, regional, and global hydrological cycles. The study calculates an overview of changes for glacier, glacier-fed rivers and lakes in Altai Tavan Bogd mountain, the Western Mongolia, based on the indexes of multispectral data and the methods typically applied in glacier studies. Were utilized an integrated approach of Normalized Difference Snow Index (NDSI) and Normalized Difference Water Index (NDWI) to combine Landsat, MODIS imagery and digital elevation model, to identify glacier cover are and quantify water storage change in lakes, and compared that with and climate parameters including precipitation, land surface temperature, evaporation, moisture. Our results show that melts of glacier at the study area has contributed to significantly increase of water storage of lakes in valley of The Altai Tavan Bogd mountain. There is hydrologic connection that lake basin is directly fed by glacier meltwater.

  2. 7. VIEW OF BASEMENT, LOOKING NORTH ALONG EAST BASEMENT WALL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. VIEW OF BASEMENT, LOOKING NORTH ALONG EAST BASEMENT WALL TOWARD TURBINES. AT RIGHT IS A WATER-POWERED EAR CORN CRUSHER (manufacturer unknown), WHICH PERFORMED THE INITIAL COARSE GRINDING OF EAR CORN Photographer: Jet T. Lowe, 1985 - Alexander's Grist Mill, Lock 37 on Ohio & Erie Canal, South of Cleveland, Valley View, Cuyahoga County, OH

  3. 22. VIEW OF THE BASEMENT FLOOR PLAN. THE BASEMENT TUNNELS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. VIEW OF THE BASEMENT FLOOR PLAN. THE BASEMENT TUNNELS WERE DESIGNED AS FALLOUT SHELTERS AND USED FOR STORAGE. THE ORIGINAL DRAWING HAS BEEN ARCHIVED ON MICROFILM. THE DRAWING WAS REPRODUCED AT THE BEST QUALITY POSSIBLE. LETTERS AND NUMBERS IN THE CIRCLES INDICATE FOOTER AND/OR COLUMN LOCATIONS. - Rocky Flats Plant, General Manufacturing, Support, Records-Central Computing, Southern portion of Plant, Golden, Jefferson County, CO

  4. LOFT. Containment and service building (TAN650) basement floor plan. Basement ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    LOFT. Containment and service building (TAN-650) basement floor plan. Basement airlock, shielded roadway, service areas, connection to control building. Kaiser engineers 6413-11-STEP/LOFT-650-A-1. Date: October 1964. INEEL index code no. 036-650-00-416-122213 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  5. basement reservoir geometry and properties

    NASA Astrophysics Data System (ADS)

    Walter, bastien; Geraud, yves; Diraison, marc

    2017-04-01

    Basement reservoirs are nowadays frequently investigated for deep-seated fluid resources (e.g. geothermal energy, groundwater, hydrocarbons). The term 'basement' generally refers to crystalline and metamorphic formations, where matrix porosity is negligible in fresh basement rocks. Geothermal production of such unconventional reservoirs is controlled by brittle structures and altered rock matrix, resulting of a combination of different tectonic, hydrothermal or weathering phenomena. This work aims to characterize the petro-structural and petrophysical properties of two basement surface analogue case studies in geological extensive setting (the Albert Lake rift in Uganda; the Ifni proximal margin of the South West Morocco Atlantic coast). Different datasets, using field structural study, geophysical acquisition and laboratory petrophysical measurements, were integrated to describe the multi-scale geometry of the porous network of such fractured and weathered basement formations. This study points out the multi-scale distribution of all the features constituting the reservoir, over ten orders of magnitude from the pluri-kilometric scale of the major tectonics structures to the infra-millimetric scale of the secondary micro-porosity of fractured and weathered basements units. Major fault zones, with relatively thick and impermeable fault core structures, control the 'compartmentalization' of the reservoir by dividing it into several structural blocks. The analysis of these fault zones highlights the necessity for the basement reservoirs to be characterized by a highly connected fault and fracture system, where structure intersections represent the main fluid drainage areas between and within the reservoir's structural blocks. The suitable fluid storage areas in these reservoirs correspond to the damage zone of all the fault structures developed during the tectonic evolution of the basement and the weathered units of the basement roof developed during pre

  6. The Optical Harness: a light-weight EMI-immune replacement for legacy electrical wiring harnesses

    NASA Astrophysics Data System (ADS)

    Stark, Jason B.; Jackson, B. Scott; Trethewey, William

    2006-05-01

    Electrical wiring harnesses have been used to interconnect control and communication equipment in mobile platforms for over a century. Although they have served this function successfully, they have three problems that are inherent in their design: they are mechanically heavy and stiff, and they are prone to electrical faults, including arcing and Electro-Magnetic Interference (EMI), and they are difficult to maintain when faults occur. These properties are all aspects of the metallic conductors used to build the harnesses. The Optical Harness TM is a photonic replacement for the legacy electrical wiring harness. The Optical Harness TM uses light-weight optical fiber to replace signal wires in an electrical harness. The original electrical connections to the equipment remain, making the Optical Harness TM a direct replacement for the legacy wiring harness. In the backshell of each connector, the electrical signals are converted to optical, and transported on optical fiber, by a deterministic, redundant and fault-tolerant optical network. The Optical Harness TM: * Provides weight savings of 40-50% and unsurpassed flexibility, relative to legacy signal wiring harnesses; * Carries its signals on optical fiber that is free from arcing, EMI, RFI and susceptibility to HPM weapons; * Is self-monitoring during operation, providing non-intrusive predictive and diagnostic capabilities.

  7. 20. VIEW OF THE BASEMENT FLOOR PLAN. THE BASEMENT AREA ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. VIEW OF THE BASEMENT FLOOR PLAN. THE BASEMENT AREA INCLUDES A UTILITY ROOM, PROCESS WASTE STORAGE AND MAINTENANCE AREAS, AND THE ENTRANCE TO AN UNDERGROUND TUNNEL LEADING TO BUILDING 881. THE ORIGINAL DRAWING HAS BEEN ARCHIVED ON MICROFILM. THE DRAWING WAS REPRODUCED AT THE BEST QUALITY POSSIBLE. LETTERS AND NUMBERS IN THE CIRCLES INDICATE FOOTER AND/OR COLUMN LOCATIONS. - Rocky Flats Plant, Uranium Rolling & Forming Operations, Southeast section of plant, southeast quadrant of intersection of Central Avenue & Eighth Street, Golden, Jefferson County, CO

  8. Viruses in the Oceanic Basement.

    PubMed

    Nigro, Olivia D; Jungbluth, Sean P; Lin, Huei-Ting; Hsieh, Chih-Chiang; Miranda, Jaclyn A; Schvarcz, Christopher R; Rappé, Michael S; Steward, Grieg F

    2017-03-07

    Microbial life has been detected well into the igneous crust of the seafloor (i.e., the oceanic basement), but there have been no reports confirming the presence of viruses in this habitat. To detect and characterize an ocean basement virome, geothermally heated fluid samples (ca. 60 to 65°C) were collected from 117 to 292 m deep into the ocean basement using seafloor observatories installed in two boreholes (Integrated Ocean Drilling Program [IODP] U1362A and U1362B) drilled in the eastern sediment-covered flank of the Juan de Fuca Ridge. Concentrations of virus-like particles in the fluid samples were on the order of 0.2 × 10 5 to 2 × 10 5  ml -1 ( n = 8), higher than prokaryote-like cells in the same samples by a factor of 9 on average (range, 1.5 to 27). Electron microscopy revealed diverse viral morphotypes similar to those of viruses known to infect bacteria and thermophilic archaea. An analysis of virus-like sequences in basement microbial metagenomes suggests that those from archaeon-infecting viruses were the most common (63 to 80%). Complete genomes of a putative archaeon-infecting virus and a prophage within an archaeal scaffold were identified among the assembled sequences, and sequence analysis suggests that they represent lineages divergent from known thermophilic viruses. Of the clustered regularly interspaced short palindromic repeat (CRISPR)-containing scaffolds in the metagenomes for which a taxonomy could be inferred (163 out of 737), 51 to 55% appeared to be archaeal and 45 to 49% appeared to be bacterial. These results imply that the warmed, highly altered fluids in deeply buried ocean basement harbor a distinct assemblage of novel viruses, including many that infect archaea, and that these viruses are active participants in the ecology of the basement microbiome. IMPORTANCE The hydrothermally active ocean basement is voluminous and likely provided conditions critical to the origins of life, but the microbiology of this vast habitat is not

  9. Intelligent electrical harness connector assembly using Bell Helicopter Textron's 'Wire Harness Automated Manufacturing System'

    NASA Astrophysics Data System (ADS)

    Springer, D. W.

    Bell Helicopter Textron, Incorporated (BHTI) installed two Digital Equipment Corporation PDP-11 computers and an American Can Inc. Ink Jet printer in 1980 as the cornerstone of the Wire Harness Automated Manufacturing System (WHAMS). WHAMS is based upon the electrical assembly philosophy of continuous filament harness forming. This installation provided BHTI with a 3 to 1 return-on-investment by reducing wire and cable identification cycle time by 80 percent and harness forming, on dedicated layout tooling, by 40 percent. Yet, this improvement in harness forming created a bottle neck in connector assembly. To remove this bottle neck, BHTI has installed a prototype connector assembly cell that integrates the WHAMS' data base and innovative computer technologies to cut harness connector assembly cycle time. This novel connector assembly cell uses voice recognition, laser identification, and animated computer graphics to help the electrician in the correct assembly of harness connectors.

  10. The interplay of fold mechanisms and basement weaknesses at the transition between Laramide basement-involved arches, north-central Wyoming, USA

    NASA Astrophysics Data System (ADS)

    Neely, Thomas G.; Erslev, Eric A.

    2009-09-01

    Horizontally-shortened, basement-involved foreland orogens commonly exhibit anastomosing networks of bifurcating basement highs (here called arches) whose structural culminations are linked by complex transition zones of diversely-oriented faults and folds. The 3D geometry and kinematics of the southern Beartooth arch transition zone of north-central Wyoming were studied to understand the fold mechanisms and control on basement-involved arches. Data from 1581 slickensided minor faults are consistent with a single regional shortening direction of 065°. Evidence for oblique-slip, vertical axis rotations and stress refraction at anomalously-oriented folds suggests formation over reactivated pre-existing weaknesses. Restorable cross-sections and 3D surfaces, constrained by surface, well, and seismic data, document blind, ENE-directed basement thrusting and associated thin-skinned backthrusting and folding along the Beartooth and Oregon Basin fault systems. Between these systems, the basement-cored Rattlesnake Mountain backthrust followed basement weaknesses and rotated a basement chip toward the basin before the ENE-directed Line Creek fault system broke through and connected the Beartooth and Oregon Basin fault systems. Slip was transferred at the terminations of the Rattlesnake Mountain fault block by pivoting to the north and tear faulting to the south. In summary, unidirectional Laramide compression and pre-existing basement weaknesses combined with fault-propagation and rotational fault-bend folding to create an irregular yet continuous basement arch transition.

  11. Moving Large Wiring-Harness Boards

    NASA Technical Reports Server (NTRS)

    Shepherd, Samuel D.; Gurman, Isaac

    1990-01-01

    Carrier for wiring-harness fabrication boards enables lone operator to move board easily and safely. Holds harness while operator fabricating, while being stored, and being transported to equipment frame for mounting. When positioned for assembly of wiring harness, board and carrier give operator easy and convenient access to wires and cables, when positioned for transfer of wiring harness to or from storage area, carrier holds board securely while moved by one person.

  12. Safety harness

    DOEpatents

    Gunter, Larry W.

    1993-01-01

    A safety harness to be worn by a worker, especially a worker wearing a plastic suit thereunder for protection in a radioactive or chemically hostile environment, which safety harness comprises a torso surrounding portion with at least one horizontal strap for adjustably securing the harness about the torso, two vertical shoulder straps with rings just forward of the of the peak of the shoulders for attaching a life-line and a pair of adjustable leg supporting straps releasibly attachable to the torso surrounding portion. In the event of a fall, the weight of the worker, when his fall is broken and he is suspended from the rings with his body angled slightly back and chest up, will be borne by the portion of the leg straps behind his buttocks rather than between his legs. Furthermore, the supporting straps do not restrict the air supplied through hoses into his suit when so suspended.

  13. ETR BASEMENT, TRA642, INTERIOR. BASEMENT. CUBICLE INTERIOR (SEE PHOTOS ID33G101 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ETR BASEMENT, TRA-642, INTERIOR. BASEMENT. CUBICLE INTERIOR (SEE PHOTOS ID-33-G-101 AND ID-33-G-102) WITH TANK AND SODIUM-RELATED APPARATUS. CAMERA STANDS BEFORE ROLL-UP DOOR SHOWN IN PHOTO ID-33-G-101. INL NEGATIVE NO. HD24-3-3. Mike Crane, Photographer, 11/2000 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  14. JWST ISIM Harness Thermal Evaluation

    NASA Technical Reports Server (NTRS)

    Kobel, Mark; Glazer, Stuart; Tuttle, Jim; Martins, Mario; Ruppel, Sean

    2008-01-01

    The James Webb Space Telescope (JWST) will be a large infrared telescope with a 6.5-meter primary mirror. Launch is planned for 2013. JWST wl1 be the premier observatory of the next decade serving thousands of astronomers worldwide. The Integrated Science Instrument Module (ISIM) is the unit that will house thc four main JWST instruments. The ISIM enclosure passively cooled to 37 Kelvin and has a tightly managed thermal budget. A significant portion of the ISIM heat load is due to parasitic heat gains from the instrument harnesses. These harnesses provide a thermal path from the Instrument Electronics Control (IEC) to the ISIM. Because of the impact of this load to the ISIM thermal design, understanding the harness parasitic heat gains is critical. To this effect, a thermal test program has been conducted in order to characterize these parasitic loads and verify harness thermal models. Recent parasitic heat loads tests resulted in the addition of a dedicated multiple stage harness radiator. In order for the radiator to efficiently reject heat from the harness, effective thermal contact conductance values for multiple harnesses had to be determined. This presentation will describe the details and the results of this test program.

  15. ROCK1-directed basement membrane positioning coordinates epithelial tissue polarity.

    PubMed

    Daley, William P; Gervais, Elise M; Centanni, Samuel W; Gulfo, Kathryn M; Nelson, Deirdre A; Larsen, Melinda

    2012-01-01

    The basement membrane is crucial for epithelial tissue organization and function. However, the mechanisms by which basement membrane is restricted to the basal periphery of epithelial tissues and the basement membrane-mediated signals that regulate coordinated tissue organization are not well defined. Here, we report that Rho kinase (ROCK) controls coordinated tissue organization by restricting basement membrane to the epithelial basal periphery in developing mouse submandibular salivary glands, and that ROCK inhibition results in accumulation of ectopic basement membrane throughout the epithelial compartment. ROCK-regulated restriction of PAR-1b (MARK2) localization in the outer basal epithelial cell layer is required for basement membrane positioning at the tissue periphery. PAR-1b is specifically required for basement membrane deposition, as inhibition of PAR-1b kinase activity prevents basement membrane deposition and disrupts overall tissue organization, and suppression of PAR-1b together with ROCK inhibition prevents interior accumulations of basement membrane. Conversely, ectopic overexpression of wild-type PAR-1b results in ectopic interior basement membrane deposition. Significantly, culture of salivary epithelial cells on exogenous basement membrane rescues epithelial organization in the presence of ROCK1 or PAR-1b inhibition, and this basement membrane-mediated rescue requires functional integrin β1 to maintain epithelial cell-cell adhesions. Taken together, these studies indicate that ROCK1/PAR-1b-dependent regulation of basement membrane placement is required for the coordination of tissue polarity and the elaboration of tissue structure in the developing submandibular salivary gland.

  16. Occupant radon exposure in houses with basements

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Franklin, E.M.; Fuoss, S.

    1995-12-31

    This study compares basement and main-level radon exposure based on bi-level week-long radon measurements, occupancy and activity data collected in normal use during heating and non-heating seasons in a geographically-stratified random sample of about 600 Minnesota homes, in response to critiques of radon measurement protocol. Basement radon (RN1) (M=4.5, SD=4.5) and main level (Rn2)(M=2.9, SD=3.4) correlation was 0.8 (p=.00), including seasonal variation. In a 101-house subsample where Rn1 >=4.0 pCi/L and Rn2 <=3.9 pCi/L, maximum household exposure in basements was 1162 pCiHrs (M=120, Sd=207), main-level 2486 pCiHrs (M-434, SD=421). In same households, persons with most basement-time maxed 100 hrs (M=13,SD=23),more » persons with most main-level time maxed 160 hrs (M=79, SD=39). Basement activities show two patterns, (1) member used it for personal domain, e.g. sleeping, and (2) household used it for general activities, e.g. TV or children`s play. Basement occupancy justifies measurement of radon in the lowest livable housing level.« less

  17. Subsurface Biodegradation in a Fractured Basement Reservoir, Shropshire, UK

    NASA Astrophysics Data System (ADS)

    Parnell, John; Baba, Mas'ud; Bowden, Stephen; Muirhead, David

    2017-04-01

    Subsurface Biodegradation in a Fractured Basement Reservoir, Shropshire, UK. John Parnell, Mas'ud Baba, Stephen Bowden, David Muirhead Subsurface biodegradation in current oil reservoirs is well established, but there are few examples of fossil subsurface degradation. Biomarker compositions of viscous and solid oil residues ('bitumen') in fractured Precambrian and other basement rocks below the Carboniferous cover in Shropshire, UK, show that they are variably biodegraded. High levels of 25-norhopanes imply that degradation occurred in the subsurface. Lower levels of 25-norhopanes occur in active seepages. Liquid oil trapped in fluid inclusions in mineral veins in the fractured basement confirm that the oil was emplaced fresh before subsurface degradation. A Triassic age for the veins implies a 200 million year history of hydrocarbon migration in the basement rocks. The data record microbial colonization of a fractured basement reservoir, and add to evidence in modern basement aquifers for microbial activity in deep fracture systems. Buried basement highs may be especially favourable to colonization, through channelling fluid flow to shallow depths and relatively low temperatures

  18. Binding of anti-basement membrane antibody to alveolar basement membrane after intratracheal gasoline instillation in rabbits.

    PubMed Central

    Yamamoto, T.; Wilson, C. B.

    1987-01-01

    A possible causal relationship has been suggested between hydrocarbon (gasoline, solvents, etc.) exposure and development of anti-basement membrane antibody-associated Goodpasture's syndrome in man. The authors evaluated the effect of hydrocarbons on pulmonary capillary permeability and binding of heterologous anti-basement membrane antibodies in the lungs after intratracheal instillation of minute amounts of unleaded gasoline into rabbits. The anti-glomerular basement membrane (GBM) antibodies used reacted with the alveolar basement membrane (ABM) in vitro by indirect immunofluorescence. The gasoline treatment altered pulmonary capillary permeability, judging from the increased accumulation of systemically administered radioiodinated bovine serum albumin in the alveolar and extravascular spaces of lungs; it also induced focal macroscopic and microscopic pulmonary histologic lesions. The gasoline caused focal in vivo binding of the anti-GBM antibodies to the ABM detectable by immunofluorescence microscopy. No binding was observed in lungs from control rabbits given saline instillations when assayed by immunofluorescence. The paired label radioisotope technique confirmed the increased antibody binding to lungs injured with gasoline (1.08 +/- 0.03 micrograms) versus 0.37 +/- 0.07 microgram after saline (P less than 0.001). These results indicate that gasoline exposure damages a pulmonary barrier that normally prevents binding of anti-GBM/ABM antibody to ABM and suggest that hydrocarbon exposure may be one of perhaps several pneumotoxic events that contribute to the episodic pulmonary hemorrhage in Goodpasture's syndrome by temporarily allowing ABM binding of anti-basement membrane antibodies. Images Figure 1 Figure 2 Figure 3 Figure 4 PMID:3548409

  19. The vascular basement membrane in the healthy and pathological brain.

    PubMed

    Thomsen, Maj S; Routhe, Lisa J; Moos, Torben

    2017-10-01

    The vascular basement membrane contributes to the integrity of the blood-brain barrier (BBB), which is formed by brain capillary endothelial cells (BCECs). The BCECs receive support from pericytes embedded in the vascular basement membrane and from astrocyte endfeet. The vascular basement membrane forms a three-dimensional protein network predominantly composed of laminin, collagen IV, nidogen, and heparan sulfate proteoglycans that mutually support interactions between BCECs, pericytes, and astrocytes. Major changes in the molecular composition of the vascular basement membrane are observed in acute and chronic neuropathological settings. In the present review, we cover the significance of the vascular basement membrane in the healthy and pathological brain. In stroke, loss of BBB integrity is accompanied by upregulation of proteolytic enzymes and degradation of vascular basement membrane proteins. There is yet no causal relationship between expression or activity of matrix proteases and the degradation of vascular matrix proteins in vivo. In Alzheimer's disease, changes in the vascular basement membrane include accumulation of Aβ, composite changes, and thickening. The physical properties of the vascular basement membrane carry the potential of obstructing drug delivery to the brain, e.g. thickening of the basement membrane can affect drug delivery to the brain, especially the delivery of nanoparticles.

  20. Diverse ages and origins of basement complexes, Luzon, Philippines

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Geary, E.E.; Harrison, T.M.; Heizler, M.

    1988-04-01

    Geological field investigations and /sup 40/Ar//sup 39/Ar ages from two basement complexes in southeast Luzon document the first known occurrences of pre-Late Cretaceous age rocks in the eastern Philippines. However, individual components within the two complexes vary in age from Late Jurassic (Caramoan basement complex) to Early Cretaceous and early Miocene (Camarines Norte-Calaguas Islands basement complex). These and other data show that southeast Luzon basement complexes are genetically diverse, and they indicate that the concept of an old, autochthonous basement in the Philippines is open to question. This supports the hypothesis that the Philippine Archipelago is an amalgamation of allochthonousmore » Mesozoic and Cenozoic island-arc, ocean-basin, and continental fragments that were assembled during the Tertiary.« less

  1. Wire harness twisting aid

    NASA Technical Reports Server (NTRS)

    Casey, E. J.; Commadore, C. C.; Ingles, M. E.

    1980-01-01

    Long wire bundles twist into uniform spiral harnesses with help of simple apparatus. Wires pass through spacers and through hand-held tool with hole for each wire. Ends are attached to low speed bench motor. As motor turns, operator moves hand tool away forming smooth twists in wires between motor and tool. Technique produces harnesses that generate less radio-frequency interference than do irregularly twisted cables.

  2. Correlated alterations in prostate basal cell layer and basement membrane

    PubMed Central

    Liu, Aijun; Wei, Lixin; Gardner, William A.; Deng, Chu-Xia; Man, Yan-Gao

    2009-01-01

    Our recent studies revealed that focal basal cell layer disruption (FBCLD) induced auto-immunoreactions represented a contributing factor for human prostate tumor progression and invasion. As the basement membrane surrounds and attaches to the basal cell layer, our current study assessed whether FBCLD would impact the physical integrity of the associated basement membrane. Paraffin sections from 25-human prostate tumors were subjected to double immunohistochemistry to simultaneously elucidate the basal cell layer and the basement membrane with corresponding biomarkers. The physical integrity of the basement membrane overlying FBCLD was examined to determine the extent of correlated alterations. Of a total of 89 FBCLD encountered, 76 (85 %) showed correlated alterations in the overlying basement membrane, which included distinct focal disruptions or fragmentations. In the remaining 13 (15%) FBCLD, the overlying basement membrane showed significant attenuation or reduction of the immunostaining intensity. The basement membrane in all or nearly all ducts or acini with p63 positive basal cells was substantially thicker and more uniform than that in ducts or acini without p63 positive basal cells, and also, a vast majority of the focal disruptions occurred near basal cells that lack p63 expression. These findings suggest that focal disruptions in the basal cell layer and alterations in the basement membrane are correlated events and that the physical and functional status of the basal cells could significantly impact the physical integrity of the overlying basement membrane. As the degradation of both the basal cell layer and the basement membrane is a pre-requisite for prostate tumor invasion or progression, ducts or acini with focally disrupted basal cell layer and basement membrane are likely at greater risk to develop invasive lesions. Thus, further elucidation of the specific molecules and mechanism associated with these events may lead to the development of a more

  3. Shoulder harnesses

    DOT National Transportation Integrated Search

    1979-06-01

    This bibliography represents literature acquired since the establishment of the National Highway Traffic Safety Administration (NHTSA) concerning the development and use of shoulder harnesses in motor vehicles. It is comprised of NHTSA contract repor...

  4. Frictional Behavior of Altered Basement Approaching the Nankai Trough

    NASA Astrophysics Data System (ADS)

    Saffer, D. M.; Ikari, M.; Rooney, T. O.; Marone, C.

    2017-12-01

    The frictional behavior of basement rocks plays an important role in subduction zone faulting and seismicity. This includes earthquakes seaward of the trench, large megathrust earthquakes where seamounts are subducting, or where the plate interface steps down to basement. In exhumed subduction zone rocks such as the Shimanto complex in Japan, slivers of basalt are entrained in mélange which is evidence of basement involvement in the fault system. Scientific drilling during the Nankai Trough Seismogenic Zone Experiment (NanTroSEIZE) recovered basement rock from two reference sites (C0011 and C0012) located seaward of the trench offshore the Kii Peninsula during Integrated Ocean Discovery Program (IODP) Expeditions 322 and 333. The basement rocks are pillow basalts that appear to be heterogeneously altered, resulting in contrasting dense blue material and more vesicular gray material. Major element geochemistry shows differences in silica, calcium oxides and loss-on-ignition between the two types of samples. Minor element geochemistry reveals significant differences in vanadium, chromium, and barium. X-ray diffraction on a bulk sample powder representing an average composition shows a phyllosilicate content of 20%, most of which is expandable clays. We performed laboratory friction experiments in a biaxial testing apparatus as either intact sample blocks, or as gouge powders. We combine these experiments with measurements of Pennsylvania slate for comparison, including a mixed-lithology intact block experiment. Intact Nankai basement blocks exhibit a coefficient of sliding friction of 0.73; for Nankai basement powder, slate powder, slate blocks and slate-on-basement blocks the coefficient of sliding friction ranges from 0.44 to 0.57. At slip rates ranging from 3x10-8 to 3x10-4 m/s we observe predominantly velocity-strengthening frictional behavior, indicating a tendency for stable slip. At rates of < 1x10-6 m/s some velocity-weakening was observed, specifically in

  5. Magnetic Basement Depth Inversion in the Space Domain

    NASA Astrophysics Data System (ADS)

    Nunes, Tiago Mane; Barbosa, Valéria Cristina F.; Silva, João Batista C.

    2008-10-01

    We present a total-field anomaly inversion method to determine both the basement relief and the magnetization direction (inclination and declination) of a 2D sedimentary basin presuming negligible sediment magnetization. Our method assumes that the magnetic intensity contrast is constant and known. We use a nonspectral approach based on approximating the vertical cross section of the sedimentary basin by a polygon, whose uppermost vertices are forced to coincide with the basin outcrop, which are presumably known. For fixed values of the x coordinates our method estimates the z coordinates of the unknown polygon vertices. To obtain the magnetization direction we assume that besides the total-field anomaly, information about the basement’s outcrops at the basin borders and the basement depths at a few points is available. To obtain stable depth-to-basement estimates we impose overall smoothness and positivity constraints on the parameter estimates. Tests on synthetic data showed that the simultaneous estimation of the irregular basement relief and the magnetization direction yields good estimates for the relief despite the mild instability in the magnetization direction. The inversion of aeromagnetic data from the onshore Almada Basin, Brazil, revealed a shallow, eastward-dipping basement basin.

  6. Positioning bars for large wire harnesses

    NASA Technical Reports Server (NTRS)

    Glessner, J. R.

    1978-01-01

    By tying positioning bars to harness, its configuration can be preserved during transport, thus facilitating installation. Harness can also be showed temporarily by placing hanging hooks on end of bar.

  7. Air exchange rates and migration of VOCs in basements and residences

    PubMed Central

    Du, Liuliu; Batterman, Stuart; Godwin, Christopher; Rowe, Zachary; Chin, Jo-Yu

    2015-01-01

    Basements can influence indoor air quality by affecting air exchange rates (AERs) and by the presence of emission sources of volatile organic compounds (VOCs) and other pollutants. We characterized VOC levels, AERs and interzonal flows between basements and occupied spaces in 74 residences in Detroit, Michigan. Flows were measured using a steady-state multi-tracer system, and 7-day VOC measurements were collected using passive samplers in both living areas and basements. A walkthrough survey/inspection was conducted in each residence. AERs in residences and basements averaged 0.51 and 1.52 h−1, respectively, and had strong and opposite seasonal trends, e.g., AERs were highest in residences during the summer, and highest in basements during the winter. Air flows from basements to occupied spaces also varied seasonally. VOC concentration distributions were right-skewed, e.g., 90th percentile benzene, toluene, naphthalene and limonene concentrations were 4.0, 19.1, 20.3 and 51.0 μg m−3, respectively; maximum concentrations were 54, 888, 1117 and 134 μg m−3. Identified VOC sources in basements included solvents, household cleaners, air fresheners, smoking, and gasoline-powered equipment. The number and type of potential VOC sources found in basements are significant and problematic, and may warrant advisories regarding the storage and use of potentially strong VOCs sources in basements. PMID:25601281

  8. Geoelectrical characterisation of basement aquifers: the case of Iberekodo, southwestern Nigeria

    NASA Astrophysics Data System (ADS)

    Aizebeokhai, Ahzegbobor P.; Oyeyemi, Kehinde D.

    2018-03-01

    Basement aquifers, which occur within the weathered and fractured zones of crystalline bedrocks, are important groundwater resources in tropical and subtropical regions. The development of basement aquifers is complex owing to their high spatial variability. Geophysical techniques are used to obtain information about the hydrologic characteristics of the weathered and fractured zones of the crystalline basement rocks, which relates to the occurrence of groundwater in the zones. The spatial distributions of these hydrologic characteristics are then used to map the spatial variability of the basement aquifers. Thus, knowledge of the spatial variability of basement aquifers is useful in siting wells and boreholes for optimal and perennial yield. Geoelectrical resistivity is one of the most widely used geophysical methods for assessing the spatial variability of the weathered and fractured zones in groundwater exploration efforts in basement complex terrains. The presented study focuses on combining vertical electrical sounding with two-dimensional (2D) geoelectrical resistivity imaging to characterise the weathered and fractured zones in a crystalline basement complex terrain in southwestern Nigeria. The basement aquifer was delineated, and the nature, extent and spatial variability of the delineated basement aquifer were assessed based on the spatial variability of the weathered and fractured zones. The study shows that a multiple-gradient array for 2D resistivity imaging is sensitive to vertical and near-surface stratigraphic features, which have hydrological implications. The integration of resistivity sounding with 2D geoelectrical resistivity imaging is efficient and enhances near-surface characterisation in basement complex terrain.

  9. NATURAL BASEMENT VENTILATION AS A RADON MITIGATION TECHNIQUE

    EPA Science Inventory

    The report documents a study of natural basement ventilation in two research houses during both the summer cooling season and the winter heating season. NOTE: Natural basement ventilation has always been recommended as a way to reduce radon levels in houses. However, its efficacy...

  10. Harnessing vision for computation.

    PubMed

    Changizi, Mark

    2008-01-01

    Might it be possible to harness the visual system to carry out artificial computations, somewhat akin to how DNA has been harnessed to carry out computation? I provide the beginnings of a research programme attempting to do this. In particular, new techniques are described for building 'visual circuits' (or 'visual software') using wire, NOT, OR, and AND gates in a visual 6modality such that our visual system acts as 'visual hardware' computing the circuit, and generating a resultant perception which is the output.

  11. Grenville age of basement rocks in Cape May NJ well: New evidence for Laurentian crust in U.S. Atlantic Coastal Plain basement Chesapeake terrane

    USGS Publications Warehouse

    Sheridan, R.E.; Maguire, T.J.; Feigenson, M.D.; Patino, L.C.; Volkert, R.A.

    1999-01-01

    The Chesapeake terrane of the U.S. mid-Atlantic Coastal Plain basement is bounded on the northwest by the Salisbury positive gravity and magnetic anomaly and extends to the southeast as far as the Atlantic coast. It underlies the Coastal Plain of Virginia, Maryland, Delaware and southern New Jersey. Rubidium/Strontium dating of the Chesapeake terrane basement yields an age of 1.025 ?? 0.036 Ga. This age is typical of Grenville province rocks of the Middle to Late Proterozoic Laurentian continent. The basement lithologies are similar to some exposed Grenville-age rocks of the Appalachians. The TiO2 and Zr/P2O5 composition of the metagabbro from the Chesapeake terrane basement is overlapped by those of the Proterozoic mafic dikes in the New Jersey Highlands. These new findings support the interpretation that Laurentian basement extends southeast as far as the continental shelf in the U.S. mid-Atlantic region. The subcrop of Laurentian crust under the mid-Atlantic Coastal Plain implies unroofing by erosion of the younger Carolina (Avalon) supracrustal terrane. Dextral-transpression fault duplexes may have caused excessive uplift in the Salisbury Embayment area during the Alleghanian orogeny. This extra uplift in the Salisbury area may have caused the subsequent greater subsidence of the Coastal Plain basement in the embayment.

  12. Spring control of wire harness loops

    NASA Technical Reports Server (NTRS)

    Curcio, P. J.

    1979-01-01

    Negator spring control guides wire harness between movable and fixed structure. It prevents electrical wire harness loop from jamming or being severed as wire moves in response to changes in position of aircraft rudder. Spring-loaded coiled cable controls wire loop regardless of rudder movement.

  13. Behavior of sandhill cranes harnessed with different satellite transmitters

    USGS Publications Warehouse

    Olsen, Glenn H.; Ellis, D.H.; Landfried, S.E.; Miller, L.H.; Klugman, S.S.; Fuller, M.R.; Vermillion, C.H.

    1992-01-01

    The effectiveness of various attachment methods and designs of platform transmitting terminals (PTT's) was tested on captive sandhill cranes (Grus canadensis) at the Patuxent Wildlife Research Center, Laurel, Maryland, during 1989-91. Combinations of attachment and transmitter designs included neoprene cord harness with batteries separate from the transmitter (2 harness designs), Teflon ribbon harness with batteries incorporated into the transmitter package (4 transmitter models), and a package attached directly to the bird with epoxy glue only. Physical effects seen on cranes wearing PTT's ranged from skin lacerations (caused by rubbing of harness material) to no observed effects (other than feather wear). The most successful harness material and design utilized a Teflon ribbon harness with the 4 ribbon ends from the transmitter forming a neck loop and a body loop joined at the sternum. Time spent by sandhill cranes performing most activities did not change after transmitter attachment using this harness method.

  14. Registration of two double rust resistant germplasms, HA-R12 and HA-R13 for confection sunflower

    USDA-ARS?s Scientific Manuscript database

    The confection sunflower (Helianthus annuus L.) germplasms HA-R12 (Reg. No. ______, PI 673104) and HA-R13 (Reg. No. ______, PI 673105) were developed by the USDA-ARS, Sunflower and Plant Biology Research Unit in collaboration with the North Dakota Agricultural Experiment Station, and released in Jul...

  15. Measure Guideline: Basement Insulation Basics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aldrich, R.; Mantha, P.; Puttagunta, S.

    2012-10-01

    This guideline is intended to describe good practices for insulating basements in new and existing homes, and is intended to be a practical resources for building contractors, designers, and also to homeowners.

  16. Virginia Department of Transportation HAR Operational Guidelines

    DOT National Transportation Integrated Search

    1995-08-01

    These guidelines have been developed to help Virginia Department of Transportation (VDOT) personnel effectively operate highway advisory radio (HAR) systems. Operators should continually bear in mind that it is of paramount importance that HAR messag...

  17. 3. AERIAL VIEW, LOOKING SOUTH, OF BUILDING 371 BASEMENT UNDER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. AERIAL VIEW, LOOKING SOUTH, OF BUILDING 371 BASEMENT UNDER CONSTRUCTION. THE BASEMENT HOUSES HEATING, VENTILATION, AND AIR CONDITIONING EQUIPMENT AND MECHANICAL UTILITIES, THE UPPER PART OF THE PLUTONIUM STORAGE VAULT AND MAINTENANCE BAY, AND SMALL PLUTONIUM PROCESSING AREAS. THE BASEMENT LEVEL IS DIVIDED INTO NEARLY EQUAL NORTH AND SOUTH PARTS BY THE UPPER PORTION OF THE PLUTONIUM STORAGE VAULT. (10/7/74) - Rocky Flats Plant, Plutonium Recovery Facility, Northwest portion of Rocky Flats Plant, Golden, Jefferson County, CO

  18. Force-dependent breaching of the basement membrane.

    PubMed

    Chang, Tammy T; Thakar, Dhruv; Weaver, Valerie M

    2017-01-01

    Clinically, non-invasive carcinomas are confined to the epithelial side of the basement membrane and are classified as benign, whereas invasive cancers invade through the basement membrane and thereby acquire the potential to metastasize. Recent findings suggest that, in addition to protease-mediated degradation and chemotaxis-stimulated migration, basement membrane invasion by malignant cells is significantly influenced by the stiffness of the associated interstitial extracellular matrix and the contractility of the tumor cells that is dictated in part by their oncogenic genotype. In this review, we highlight recent findings that illustrate unifying molecular mechanisms whereby these physical cues contribute to tissue fibrosis and malignancy in three epithelial organs: breast, pancreas, and liver. We also discuss the clinical implications of these findings and the biological properties and clinical challenges linked to the unique biology of each of these organs. Copyright © 2017 International Society of Matrix Biology. Published by Elsevier B.V. All rights reserved.

  19. Basement structures over Rio Grande Rise from gravity inversion

    NASA Astrophysics Data System (ADS)

    Constantino, Renata; Hackspacker, Peter Christian; Anderson de Souza, Iata; Sousa Lima Costa, Iago

    2017-04-01

    In this study, we show that from satellite-derived gravity field, bathymetry and sediment thicknesses, it is possible to give a 3-D model of the basement over oceanic areas, and for this purpose, we have chosen the Rio Grande Rise, in South Atlantic Ocean, to build a gravity-equivalent basement topography. The advantages of the method applied in this study are manifold: does not depend directly on reflection seismic data; can be applied quickly and with fewer costs for acquiring and interpreting the data; and as the main result, presents the physical surface below the sedimentary layer, which may be different from the acoustic basement. We evaluated the gravity effect of the sediments using the global sediment thickness model of NOAA, fitting a sediment compaction model to observed density values from Deep Sea Drilling Program (DSDP) reports. The Global Relief Model ETOPO1 and constraining data from seismic interpretation on crustal thickness are integrated in the gravity inversion procedure. The modeled Moho depth values vary between 6 to 27 km over the area, being thicker under the Rio Grande Rise and also in the direction of São Paulo Plateau. The inversion for the gravity-equivalent basement topography is applied for a gravity residual data, which is free from the gravity effect of sediments and from the gravity effect of the estimated Moho interface. A description of the basement depth over Rio Grande Rise area is unprecedented in the literature, however, our results could be compared to in situ data, provided by DSDP, and a small difference of only 9 m between our basement depth and leg 516 F was found. Our model shows a rift crossing the entire Rio Grande Rise deeper than previously presented in literature, with depths up to 5 km in the East Rio Grande Rise (ERGR) and deeper in the West Rio Grande Rise (WRGR), reaching 6.4 km. We find several short-wavelengths structures not present in the bathymetry data. Seamounts, guyots and fracture zones are much more

  20. Geochemical provenance of Florida basement components

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Heatherington, A.L.; Mueller, P.A.; Dallmeyer, R.D.

    1993-03-01

    The pre-Cretaceous basement of Florida is generally considered to be exotic with respect to Proterozoic Laurentia. Paleontologic and paleomagnetic evidence have suggested a Gondwanan provenance for the Floridan basement, as either a peri-Gondwanide terrane or as a rifted block of the West African craton. The report of generally similar lithologic sequences and a record of similar Ar-Ar cooling ages in some Floridan and West African lithologic units has led to very specific correlations between these units. U-Pb, Sm-Nd, and Rb-Sr geochronologic studies as well as isotopic and elemental abundance data have been used to evaluate the validity of these correlations.more » Results indicate: (1) geochemical similarities between volcanic rocks of northeastern Florida and a Pan-African metavolcanic sequence (Niokola-Koba group) exposed in Senegal; (2) an absence of a Grenvillian-age (i.e., Laurentian) component in zircons separated from a Paleozoic Suwanee basin sandstone; and (3) whole-rock Sm-Nd and U-Pb zircon evidence for an Archean ([approximately]3.0 Ga) component in the neo-Proterozoic Osceola granitoid(s). Although silicic rocks from throughout Florida have Nd model ages (T[sub DM]) that are predominantly Grenvillian (1.1--1.4 Ga), the absence of a Grenvillian component in zircons separated from granite and sandstone suggests that the model ages represent a mixture of older and younger components. Overall, the evidence for Birimian ([approximately]2.1 Ga) and Liberian ([approximately]3.0 Ga) age components in the Florida basement are consistent with its origin as a rifted block of cratonic Gondwana. In addition to demonstrating a strong affinity between the Florida basement and cratonic West Africa/northern South America, these data provide a basis for comparison with other circum-Atlantic terranes traditionally described as Avalonian/Cadomian, etc.« less

  1. Registration of two confection sunflower germplasm Lines, HA-R10 and HA-R11, Resistant to sunflower rust

    USDA-ARS?s Scientific Manuscript database

    Two confection sunflower (Helianthus annuus L.) germplasm lines, HA-R10 (Reg. No.xxx, PI670043) and HA-R11 (Reg. No.xxx, PI670044) were developed by the USDA-ARS Sunflower and Plant Biology Research Unit in collaboration with the North Dakota Agricultural Experiment Station and released December, 20...

  2. 26. EXCAVATION OF EAST (FRONT) BASEMENT WELL AND DRAINAGE SYSTEM, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. EXCAVATION OF EAST (FRONT) BASEMENT WELL AND DRAINAGE SYSTEM, WITH ARCHED ENTRY INTO BASEMENT UNDER FRONT ENTRY IN BACKGROUND, LOOKING NORTH (NOTE GALLETING IN BRICK FOUNDATION) - Belair, Tulip Grove Drive, Belair-at-Bowie, Bowie, Prince George's County, MD

  3. Type IV Collagens and Basement Membrane Diseases: Cell Biology and Pathogenic Mechanisms.

    PubMed

    Mao, Mao; Alavi, Marcel V; Labelle-Dumais, Cassandre; Gould, Douglas B

    2015-01-01

    Basement membranes are highly specialized extracellular matrices. Once considered inert scaffolds, basement membranes are now viewed as dynamic and versatile environments that modulate cellular behaviors to regulate tissue development, function, and repair. Increasing evidence suggests that, in addition to providing structural support to neighboring cells, basement membranes serve as reservoirs of growth factors that direct and fine-tune cellular functions. Type IV collagens are a major component of all basement membranes. They evolved along with the earliest multicellular organisms and have been integrated into diverse fundamental biological processes as time and evolution shaped the animal kingdom. The roles of basement membranes in humans are as complex and diverse as their distributions and molecular composition. As a result, basement membrane defects result in multisystem disorders with ambiguous and overlapping boundaries that likely reflect the simultaneous interplay and integration of multiple cellular pathways and processes. Consequently, there will be no single treatment for basement membrane disorders, and therapies are likely to be as varied as the phenotypes. Understanding tissue-specific pathology and the underlying molecular mechanism is the present challenge; personalized medicine will rely upon understanding how a given mutation impacts diverse cellular functions. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. Bunkhouse basement interior showing storage area and a conveyor belt ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Bunkhouse basement interior showing storage area and a conveyor belt (circa 1936) used to unload dry goods into the basement through an opening on the east side of the bunkhouse. - Sespe Ranch, Bunkhouse, 2896 Telegraph Road, Fillmore, Ventura County, CA

  5. Avoid the Wet Basement Blues: Construction Methods Guarantee Success

    ERIC Educational Resources Information Center

    Domermuth, David

    2006-01-01

    A damp basement can be a nightmare, especially after mildew creates its eye-watering, nose-offending stench. There are two enemies to overcome: damp air condensing on interior walls and ground water penetrating the exterior. One can address condensation by drying or heating the air in a basement to raise it above the dew point. The simple way to…

  6. 6. INTERIOR VIEW OF NORTH ENTRANCE TO BASEMENT SHOWING WORKBENCH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. INTERIOR VIEW OF NORTH ENTRANCE TO BASEMENT SHOWING WORKBENCH AT PHOTO LEFT AND ONE OF TWO DOORWAYS TO MAIN BASEMENT AREA AT PHOTO RIGHT. VIEW TO NORTH. - Bishop Creek Hydroelectric System, Control Station, Worker Cottage, Bishop Creek, Bishop, Inyo County, CA

  7. SSME Electrical Harness and Cable Development and Evolution

    NASA Technical Reports Server (NTRS)

    Abrams, Russ; Heflin, Johnny; Burns, Bob; Camper, Scott J.; Hill, Arthur J.

    2010-01-01

    The Space Shuttle Main Engine (SSME) electrical harness and cable system consists of the various interconnecting devices necessary for operation of complex rocket engine functions. Thirty seven harnesses incorporate unique connectors, backshell adapters, conductors, insulation, shielding, and physical barriers for a long maintenance-free life while providing the means to satisfy performance requirements and to mitigate adverse environmental influences. The objective of this paper is to provide a description of the SSME electrical harness and cable designs as well as the development history and lessons learned.

  8. [Vascular thrombosis and pulmonary thrombo-embolism due to harness suspension].

    PubMed

    Pisati, G; Cerri, S; Achille, G; Rossi, G; Lorenzi, G

    2007-01-01

    In many sports (such as rock-climbing and caving) and working activities (e.g., construction and maintenance of buildings, pruning of lung-trunked trees, abseiling in wells) people run the risk of falling from a height. To prevent the effects of any potential fall, personalprotection devices consisting of at least a body holding device (i.e. a harness of some type), a lanyard and a reliable anchor are used. Reporting on the occurrence of vascular thrombosis in subjects undergoing prolonged hanging in a harness, either for work or recreation. We investigated patients treated for vascular thrombosis in our hospital in the last 5 years to identify subjects with frequent use of a harness. We identified a 36-year-old rock-climber who developed pulmonary thrombo-embolism and infarction 5 days after he had been wearing a harness for 12 hours consecutively, and a 32 year-old worker who often used a harness to fix wire-nettings to prevent rocks falling from steep places and suffered thrombosis of the left superficial femoral artery. A feature of both cases was the considerable length of time spent hanging in the harness and the absence of alternative risk factors for thrombosis. Prolonged hanging in a harness can be dangerous in itself because it can produce vascular thrombosis. Reduction of intravascular blood flow (stasis) and compression of the femoral veins by harness groin straps were the likely pathogenetic mechanisms of the described diseases. The importance is stressed of prevention, which must be based on planned regular breaks in the hanging position, checking on the fit and comfort level of the harness before it is first used, as well as medical surveillance of the subjects who spend prolonged periods in a harness for work or recreation.

  9. Region IV Transit Workshop: Harnessing the Private Sector

    DOT National Transportation Integrated Search

    1988-09-01

    This Report constitutes the Proceedings of the Region IV Transit Workshop: : Harnessing the Private Sector. Included in this document is a general report of : the activities of the Workshop. : The purpose ot the Region IV Transit Workshop: Harnessing...

  10. The morphology and nature of the East Arctic ocean acoustic basement

    NASA Astrophysics Data System (ADS)

    Rekant, Pavel

    2017-04-01

    As the result of the thorough interpretation and cross-correlation of the large seismic dataset (>150000 km and >600 seismic lines), the depth structure map of the acoustic basement was constrained. Tectonic framework, basement surface morphology and linkage of the deep basin structures with shelves ones, was significantly clarified based on the map. It becomes clear that most morphostructures presently located within deep-water basin are tectonically connected with shelf structures. Acoustic basement contains a number of pre-Cambrian, Caledonian and Mesozoic consolidated blocks. The basement heterogeneity is highlighted by faults framework and basement surface morphology differences, as well thickness and stratigraphy of the sediment cover. The deepest basins of the East Arctic - Hanna Trough, North Chukchi and Podvodnikov Basins form a united mega-depression, wedged between pre-Cambrian continental blocks (Chukchi Borderland - Mendeleev Rise - Toll Saddle) from the north and the Caledonian deformation front from the south. The basement age/origin speculations are consistent with paleontological and U-Pb zircon ages from dredged rock samples. Most of morphological boundaries in the modern Arctic differ considerably from the tectonic framework. Only part of the Arctic morphostructures is constrained by tectonic boundaries. They are: eastern slope of the Lomonosov Ridge, continental slope in the Laptev Sea, upper continental slope in the Podvodnikov Basin, southern slope of the North Chukchi Basin and borders of the Chukchi Borderland. The rest significant part of modern morphological boundaries are caused by sedimentation processes.

  11. Reliable Wiring Harness

    NASA Technical Reports Server (NTRS)

    Gaspar, Kenneth C.

    1987-01-01

    New harness for electrical wiring includes plugs that do not loosen from vibration. Ground braids prevented from detaching from connectors and constrained so braids do not open into swollen "birdcage" sections. Spring of stainless steel encircles ground braid. Self-locking connector contains ratchet not only preventing connector from opening, but tightens when vibrated.

  12. 14 CFR 121.311 - Seats, safety belts, and shoulder harnesses.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Seats, safety belts, and shoulder harnesses... § 121.311 Seats, safety belts, and shoulder harnesses. (a) No person may operate an airplane unless... belt and shoulder harness that meets the applicable requirements specified in § 25.785 of this chapter...

  13. 14 CFR 121.311 - Seats, safety belts, and shoulder harnesses.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Seats, safety belts, and shoulder harnesses... § 121.311 Seats, safety belts, and shoulder harnesses. (a) No person may operate an airplane unless... belt and shoulder harness that meets the applicable requirements specified in § 25.785 of this chapter...

  14. 14 CFR 121.311 - Seats, safety belts, and shoulder harnesses.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Seats, safety belts, and shoulder harnesses... § 121.311 Seats, safety belts, and shoulder harnesses. (a) No person may operate an airplane unless... belt and shoulder harness that meets the applicable requirements specified in § 25.785 of this chapter...

  15. 14 CFR 121.311 - Seats, safety belts, and shoulder harnesses.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Seats, safety belts, and shoulder harnesses... § 121.311 Seats, safety belts, and shoulder harnesses. (a) No person may operate an airplane unless... belt and shoulder harness that meets the applicable requirements specified in § 25.785 of this chapter...

  16. 14 CFR 121.311 - Seats, safety belts, and shoulder harnesses.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Seats, safety belts, and shoulder harnesses... § 121.311 Seats, safety belts, and shoulder harnesses. (a) No person may operate an airplane unless... belt and shoulder harness that meets the applicable requirements specified in § 25.785 of this chapter...

  17. Precambrian crystalline basement map of Idaho-an interpretation of aeromagnetic anomalies

    USGS Publications Warehouse

    Sims, P.K.; Lund, Karen; Anderson, E.

    2005-01-01

    Idaho lies within the northern sector of the U.S. Cordillera astride the boundary between the Proterozoic continent (Laurentia) to the east and the Permian to Jurassic accreted terranes to the west. The continental basement is mostly covered by relatively undeformed Mesoproterozoic metasedimentary rocks and intruded or covered by Phanerozoic igneous rocks; accordingly, knowledge of the basement geology is poorly constrained. Incremental knowledge gained since the pioneering studies by W. Lindgren, C.P. Ross, A.L. Anderson, A. Hietanen, and others during the early- and mid-1900's has greatly advanced our understanding of the general geology of Idaho. However, knowledge of the basement geology remains relatively poor, partly because of the remoteness of much of the region plus the lack of a stimulus to decipher the complex assemblage of high-grade gneisses and migmatite of central Idaho. The availability of an updated aeromagnetic anomaly map of Idaho (North American Magnetic Anomaly Group, 2002) provides a means to determine the regional Precambrian geologic framework of the State. The combined geologic and aeromagnetic data permit identification of previously unrecognized crystalline basement terranes, assigned to Archean and Paleoproterozoic ages, and the delineation of major shear zones, which are expressed in the aeromagnetic data as linear negative anomalies (Finn and Sims, 2004). Limited geochronologic data on exposed crystalline basement aided by isotopic studies of zircon inheritance, particularly Bickford and others (1981) and Mueller and others (1995), provide much of the geologic background for our interpretation of the basement geology. In northwestern United States, inhomogeneities in the basement inherited from Precambrian tectogenesis controlled many large-scale tectonic features that developed during the Phanerozoic. Two basement structures, in particular, provided zones of weakness that were repeatedly rejuvenated: (1) northeast-trending ductile

  18. Anti-glomerular basement membrane blood test

    MedlinePlus

    ... the part of the kidney that helps filter waste and extra fluid from the blood. Anti-glomerular basement membrane antibodies are antibodies against this membrane. They can lead to kidney damage. This article describes the blood test to detect these antibodies.

  19. Extracellular chloride signals collagen IV network assembly during basement membrane formation

    PubMed Central

    Cummings, Christopher F.; Pedchenko, Vadim; Brown, Kyle L.; Colon, Selene; Rafi, Mohamed; Jones-Paris, Celestial; Pokydeshava, Elena; Liu, Min; Pastor-Pareja, Jose C.; Stothers, Cody; Ero-Tolliver, Isi A.; McCall, A. Scott; Vanacore, Roberto; Bhave, Gautam; Santoro, Samuel; Blackwell, Timothy S.; Zent, Roy; Pozzi, Ambra

    2016-01-01

    Basement membranes are defining features of the cellular microenvironment; however, little is known regarding their assembly outside cells. We report that extracellular Cl− ions signal the assembly of collagen IV networks outside cells by triggering a conformational switch within collagen IV noncollagenous 1 (NC1) domains. Depletion of Cl− in cell culture perturbed collagen IV networks, disrupted matrix architecture, and repositioned basement membrane proteins. Phylogenetic evidence indicates this conformational switch is a fundamental mechanism of collagen IV network assembly throughout Metazoa. Using recombinant triple helical protomers, we prove that NC1 domains direct both protomer and network assembly and show in Drosophila that NC1 architecture is critical for incorporation into basement membranes. These discoveries provide an atomic-level understanding of the dynamic interactions between extracellular Cl− and collagen IV assembly outside cells, a critical step in the assembly and organization of basement membranes that enable tissue architecture and function. Moreover, this provides a mechanistic framework for understanding the molecular pathobiology of NC1 domains. PMID:27216258

  20. Radiolytic hydrogen production in basaltic basement of the South Pacific Gyre

    NASA Astrophysics Data System (ADS)

    Dzaugis, M. E.; Spivack, A. J.; Dunlea, A. G.; Murray, R. W.; Kelley, K. A.; D'Hondt, S. L.

    2013-12-01

    Water radiolysis is the decomposition of water molecules due to interactions with ionizing radiation from the natural decay of radioactive elements, such as uranium (238U, 235U), thorium (232Th) and potassium (40K). This abiotic process produces electron donors (e.g., H2) and acceptors (e.g., O2) that microorganisms can metabolize for energy. Although water radiolysis has been examined in deep continental crust (Lin et al., 2005) and marine sediment (Blair et al., 2007), it has not been rigorously addressed in oceanic basement. The submarine depth to which life extends on Earth, and the potential for life in basaltic aquifers of other worlds (such as Mars and Europa), may depend on radiolytic production of electron donors and acceptors. In order to quantify the extent to which water radiolysis occurs in the subseafloor basaltic basement, we (i) quantified radioactive element concentrations of basement samples from Integrated Ocean Drilling Program (IODP) Expedition 329 and (ii) developed a quantitative model of H2 production by water radiolysis in the basement aquifer. Modeling radiolytic production of H2 in oceanic basement is difficult because the basement is a heterogeneous environment. Microscale changes in physical properties and chemical composition cause microscale variation in water radiolysis within the basement. During radioactive decay, alpha particles, beta particles and gamma rays are emitted, each with a spectrum of characteristic energies. The distance over which radiation is attenuated depends on the kind of radiation (alpha, beta or gamma), initial energy, and the absorbing material. These properties and the concentration of radioactive elements provide the basis for our preliminary model. We are using inductively coupled plasma emission spectroscopy (ICP-ES), mass spectrometry (ICP-MS) and laser ablation (LA ICP-MS) to map variation in radioelement concentrations from phase to phase (e.g., across successive alteration halos to unaltered rock). The

  1. Ivory Basements and Ivory Towers

    ERIC Educational Resources Information Center

    Fitzgerald, Tanya

    2012-01-01

    The metaphors of the ivory tower and ivory basement are used in this chapter to reflect how many women understand and experience the academy. The ivory tower signifies a place that is protected, a place of privilege and authority and a place removed from the outside world (and consequently the rigours of the market place). The ivory tower, by…

  2. Effects of pressure and electrical charge on macromolecular transport across bovine lens basement membrane.

    PubMed

    Ferrell, Nicholas; Cameron, Kathleen O; Groszek, Joseph J; Hofmann, Christina L; Li, Lingyan; Smith, Ross A; Bian, Aihua; Shintani, Ayumi; Zydney, Andrew L; Fissell, William H

    2013-04-02

    Molecular transport through the basement membrane is important for a number of physiological functions, and dysregulation of basement membrane architecture can have serious pathological consequences. The structure-function relationships that govern molecular transport in basement membranes are not fully understood. The basement membrane from the lens capsule of the eye is a collagen IV-rich matrix that can easily be extracted and manipulated in vitro. As such, it provides a convenient model for studying the functional relationships that govern molecular transport in basement membranes. Here we investigate the effects of increased transmembrane pressure and solute electrical charge on the transport properties of the lens basement membrane (LBM) from the bovine eye. Pressure-permeability relationships in LBM transport were governed primarily by changes in diffusive and convective contributions to solute flux and not by pressure-dependent changes in intrinsic membrane properties. The solute electrical charge had a minimal but statistically significant effect on solute transport through the LBM that was opposite of the expected electrokinetic behavior. The observed transport characteristics of the LBM are discussed in the context of established membrane transport modeling and previous work on the effects of pressure and electrical charge in other basement membrane systems. Copyright © 2013 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  3. Cover sequence stratigraphy and structure: Salem Church basement culmination, Georgia Blue Ridge

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, L.; Tull, J.F.

    The Salem Church anticline SW of Jasper, Georgia in the western Blue Ridge is roughly an oval shaped structural dome with its long axis trending NE-SW. The anticline is cored by the Grenville age Corbin Gneiss which represents allochthonous North American basement. In debate for decades has been the age and origin of several kilometers of poly-deformed cover sequence rocks which were metamorphosed to greenschist facies and were probably transported over a long distance inland after their deposition. The stratigraphy of the cover sequence exhibits rapid lithofacies changes. At most localities, the basement is overlain by a 500--600 m thickmore » coarse clastic unit sourced from the basement rocks, composed mainly of metaconglomerate, metasandstone and metadiamictite. A thin unit less than 20 m thick of sericite phyllite occurs between the basement and the coarse clastic unit along the SE limb of the anticline but pinches out to the MW. A relatively sharp stratigraphic contact occurs between quartzite unit and overlying dark colored metagreywackes and metadiamictites containing distinctive cobbles and boulders of granitic and gneissic basement rocks up to 1 meter in length. This unit is about 100 m thick in the SW but thins rapidly towards the NE. It grades up into a geographically widespread graphitic phyllite which encircles most of the anticline. Unlike the cover sequence above the corbin basement west of Waleska, Georgia, no carbonate is found in this area.« less

  4. NCCS Regression Test Harness

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tharrington, Arnold N.

    2015-09-09

    The NCCS Regression Test Harness is a software package that provides a framework to perform regression and acceptance testing on NCCS High Performance Computers. The package is written in Python and has only the dependency of a Subversion repository to store the regression tests.

  5. 14 CFR 137.42 - Fastening of safety belts and shoulder harnesses.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Fastening of safety belts and shoulder... AGRICULTURAL AIRCRAFT OPERATIONS Operating Rules § 137.42 Fastening of safety belts and shoulder harnesses. No... belt and shoulder harness properly secured about that person except that the shoulder harness need not...

  6. 14 CFR 137.42 - Fastening of safety belts and shoulder harnesses.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Fastening of safety belts and shoulder... AGRICULTURAL AIRCRAFT OPERATIONS Operating Rules § 137.42 Fastening of safety belts and shoulder harnesses. No... belt and shoulder harness properly secured about that person except that the shoulder harness need not...

  7. 14 CFR 137.42 - Fastening of safety belts and shoulder harnesses.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Fastening of safety belts and shoulder... AGRICULTURAL AIRCRAFT OPERATIONS Operating Rules § 137.42 Fastening of safety belts and shoulder harnesses. No... belt and shoulder harness properly secured about that person except that the shoulder harness need not...

  8. 14 CFR 137.42 - Fastening of safety belts and shoulder harnesses.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Fastening of safety belts and shoulder... AGRICULTURAL AIRCRAFT OPERATIONS Operating Rules § 137.42 Fastening of safety belts and shoulder harnesses. No... belt and shoulder harness properly secured about that person except that the shoulder harness need not...

  9. 14 CFR 137.42 - Fastening of safety belts and shoulder harnesses.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Fastening of safety belts and shoulder... AGRICULTURAL AIRCRAFT OPERATIONS Operating Rules § 137.42 Fastening of safety belts and shoulder harnesses. No... belt and shoulder harness properly secured about that person except that the shoulder harness need not...

  10. The Acinar Cage: Basement Membranes Determine Molecule Exchange and Mechanical Stability of Human Breast Cell Acini.

    PubMed

    Gaiko-Shcherbak, Aljona; Fabris, Gloria; Dreissen, Georg; Merkel, Rudolf; Hoffmann, Bernd; Noetzel, Erik

    2015-01-01

    The biophysical properties of the basement membrane that surrounds human breast glands are poorly understood, but are thought to be decisive for normal organ function and malignancy. Here, we characterize the breast gland basement membrane with a focus on molecule permeation and mechanical stability, both crucial for organ function. We used well-established and nature-mimicking MCF10A acini as 3D cell model for human breast glands, with ether low- or highly-developed basement membrane scaffolds. Semi-quantitative dextran tracer (3 to 40 kDa) experiments allowed us to investigate the basement membrane scaffold as a molecule diffusion barrier in human breast acini in vitro. We demonstrated that molecule permeation correlated positively with macromolecule size and intriguingly also with basement membrane development state, revealing a pore size of at least 9 nm. Notably, an intact collagen IV mesh proved to be essential for this permeation function. Furthermore, we performed ultra-sensitive atomic force microscopy to quantify the response of native breast acini and of decellularized basement membrane shells against mechanical indentation. We found a clear correlation between increasing acinar force resistance and basement membrane formation stage. Most important native acini with highly-developed basement membranes as well as cell-free basement membrane shells could both withstand physiologically relevant loads (≤ 20 nN) without loss of structural integrity. In contrast, low-developed basement membranes were significantly softer and more fragile. In conclusion, our study emphasizes the key role of the basement membrane as conductor of acinar molecule influx and mechanical stability of human breast glands, which are fundamental for normal organ function.

  11. The role of basal cells in adhesion of columnar epithelium to airway basement membrane.

    PubMed

    Evans, M J; Plopper, C G

    1988-08-01

    In this report, we present a new concept of the role of the basal cell in airway epithelium. Previously, the basal cell was thought to be the progenitor cell for the columnar epithelium. However, several studies have shown that this concept may not be correct. The morphologic aspects of the basal cell suggest that it could play a role in adhesion of the columnar epithelium to the basement membrane. Basal cells form attachments with columnar cells (desmosomes) and with the basement membrane (hemidesmosomes). Columnar cells do not form hemidesmosome attachments with the basement membrane. Basal cells could strengthen the adhesion of columnar cells to the basement membrane by forming hemidesmosome attachments to the basement membrane and desmosome attachments with adjacent columnar cells. Incidental evidence from 2 existing publications concerning airway microanatomy support this concept. As columnar cells grow taller, the proportion of the cell surface in contact with the basement membrane becomes progressively smaller, and thus the cell surface area related to adhesion also becomes smaller. It was found that the number of basal cells per millimeter of basement membrane was closely related to the height of the columnar cell epithelium (r = 0.98), but not to the number of columnar cells (r = 0.42). The consistency of the relationship between increased columnar cell height (and thus decreased surface area for adhesion) and the number of basal cells present (r = 0.98) supports the concept that the basal cell plays a role in adhesion of columnar cells to the basement membrane.(ABSTRACT TRUNCATED AT 250 WORDS)

  12. 27. EXCAVATION OF EAST (FRONT) BASEMENT WELL AND DRAINAGE SYSTEM, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. EXCAVATION OF EAST (FRONT) BASEMENT WELL AND DRAINAGE SYSTEM, WITH ARCHED ENTRY INTO BASEMENT UNDER FRONT ENTRY IN BACKGROUND, LOOKING NORTH (NOTE GALLETING IN BRICK FOUNDATION) BUT CLOSER RANGE SHOWING BRICK STRUCTURE WHICH CARRIED WATER FROM THE GUTTER DRAIN PIPE INTO THE BRICK DRAIN ALONG THE GROUND AND AWAY FROM THE FOUNDATION OF THE HOUSE - Belair, Tulip Grove Drive, Belair-at-Bowie, Bowie, Prince George's County, MD

  13. 22. VIEW OF THE BASEMENT AND MEZZANINE FLOOR PLANS. ALL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. VIEW OF THE BASEMENT AND MEZZANINE FLOOR PLANS. ALL MECHANICAL AND ELECTRICAL UTILITY EQUIPMENT IS CONTAINED IN THE BASEMENT. THE MEZZANINE CONTAINS OFFICES. THE DRAWING WAS REPRODUCED AT THE BEST QUALITY POSSIBLE. LETTERS AND NUMBERS IN THE CIRCLES INDICATE FOOTER AND/OR COLUMN LOCATIONS. - Rocky Flats Plant, Non-Nuclear Production Facility, South of Cottonwood Avenue, west of Seventh Avenue & east of Building 460, Golden, Jefferson County, CO

  14. Precambrian basement geologic map of Montana; an interpretation of aeromagnetic anomalies

    USGS Publications Warehouse

    Sims, P.K.; O'Neill, J. M.; Bankey, Viki; Anderson, E.

    2004-01-01

    Newly compiled aeromagnetic anomaly data of Montana, in conjunction with the known geologic framework of basement rocks, have been combined to produce a new interpretive geologic basement map of Montana. Crystalline basement rocks compose the basement, but are exposed only in the cores of mountain ranges in southwestern Montana. Principal features deduced from the map are: (1) A prominent northeast-trending, 200-km-wide zone of spaced negative anomalies, which extends more than 700 km from southwestern Montana's Beaverhead Mountains to the Canadian border and reflects suturing of the Archean Mexican Hat Block against the Archean Wyoming Province along the Paleoproterozoic Trans-Montana Orogen (new name) at about 1.9-1.8 Ga; (2) North-northwest-trending magnetic lows in northeastern Montana, which reflect the 1.9-1.8 Ga Trans-Hudson Orogen and truncate the older Trans-Montana Zone; and (3) Subtle northwest- and west-trending negative anomalies in central and western Montana, which represent the northernmost segment of brittle-ductile transcurrent faults of the newly recognized Mesoproterozoic Trans-Rocky Mountain fault system. Structures developed in the Proterozoic provided zones of crustal weakness reactivated during younger Proterozoic and Phanerozoic igneous and tectonic activity. For example, the Trans-Montana Zone guided basement involved thrust faulting in southwestern Montana during the Sevier Orogeny. The Boulder Batholith and associated ore deposits and the linear belt of alkaline intrusions to the northeast were localized along a zone of weakness between the Missouri River suture and the Dillon shear zone of the Trans-Montana Orogen. The northwest-trending faults of Trans-Rocky Mountain system outline depocenters for sedimentary rocks in the Belt Basin. This fault system provided zones of weakness that guided Laramide uplifts during basement crustal shortening. Northwest-trending zones have been locally reactivated during Neogene basin-range extension.

  15. Design Process Improvement for Electric CAR Harness

    NASA Astrophysics Data System (ADS)

    Sawatdee, Thiwarat; Chutima, Parames

    2017-06-01

    In an automobile parts design company, the customer satisfaction is one of the most important factors for product design. Therefore, the company employs all means to focus its product design process based on the various requirements of customers resulting in high number of design changes. The objective of this research is to improve the design process of the electric car harness that effects the production scheduling by using Fault Tree Analysis (FTA) and Failure Mode and Effect Analysis (FMEA) as the main tools. FTA is employed for root cause analysis and FMEA is used to ranking a High Risk Priority Number (RPN) which is shows the priority of factors in the electric car harness that have high impact to the design of the electric car harness. After the implementation, the improvements are realized significantly since the number of design change is reduced from 0.26% to 0.08%.

  16. LPT. Shield test facility (TAN645 and 646). Basement and subbasement ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    LPT. Shield test facility (TAN-645 and -646). Basement and sub-basement plan. Stairway plans and details. Ralph M. Parsons 1229-17 ANP/GE-6-645-A-2. April 1957. Approved by INEEL Classification Office for public release. INEEL index code no. 037-0645/0646-00-693-107348 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  17. Basement control of structure in the Gettysburg rift basin, Pennsylvania and Maryland

    NASA Astrophysics Data System (ADS)

    Root, Samuel I.

    1989-09-01

    Jurassic faulting formed the 93 km long Gettysburg basin as an extensional half graben paralleling the basement structural grain. Preserved in the basin are rift-related Carnian to Rhaetian strata that were tilted 20-30° NW into a SE dipping, listric normal fault at the northwest border of the basin. Vertical displacement on the border fault approaches 10 km. The border fault developed parallel to the trend of the terminal Paleozoic Alleghenian South Mountain cleavage of the Blue Ridge basement along 80% of its extent. However, it is only roughly parallel to discordant to dip of the cleavage. Relationship of cleavage and later border faulting may be the result of persistent reactivation of the original Appalachian continental margin. Local complex structures in the half graben are related to reactivation of two subvertical, pre-Mesozoic faults that transect basement structural grain (cleavage) at a large angle. The northern Shippensburg fault was reactivated during basin normal faulting, offsetting the border fault in a right-lateral sense by 3.5 km and forming within the basin a fold and a fault sliver of basement. The southern Carbaugh-Marsh Creek fault was not reactivated, but is the locus of a 20°-30° change of trend of both the basement cleavage and later border fault. However, two large, NW trending, left-lateral wrench faults, antithetic to the Carbaugh-March Creek fault, developed here offsetting the border fault and forming en echelon folds and horst blocks of basement rock within the basin.

  18. The Fiber Grating Sensors Applied in the Deformation Measurement of Shipborne Antenna Basement

    NASA Astrophysics Data System (ADS)

    Liu, Yong; Chen, Jiahong; Zhao, Wenhua

    2016-02-01

    The optical fiber grating sensor is a novel fibre-optical passive device, its reflecting optical spectrum is linearly related with strain. It is broadly applied in the structural monitoring industry. Shipborne antenna basement is the basic supporting structure for the radar tracking movement. The bending deformation of the basement caused by ship attitude changing influences the antenna tracking precision, According to the structure of shipborne antenna basement, a distributed strain testing method based on the fibre grating sensor is approved to measure the bending deformation under the bending force. The strain-angle model is built. The regularity of the strain distribution is obtained. The finite element method is used to analyze the deformation of the antenna basement. The measuring experiment on the contractible basement mould is carried out to verify the availability of the method. The result of the experiment proves that the model is effective to apply in the deformation measurement. It provides an optimized method for the distribution of the fiber grating sensor in the actual measuring process.

  19. Evaluation of Cable Harness Post-Installation Testing. Part B

    NASA Technical Reports Server (NTRS)

    King, M. S.; Iannello, C. J.

    2011-01-01

    The Cable Harness Post-Installation Testing Report was written in response to an action issued by the Ares Project Control Board (PCB). The action for the Ares I Avionics & Software Chief Engineer and the Avionics Integration and Vehicle Systems Test Work Breakdown Structure (WBS) Manager in the Vehicle Integration Office was to develop a set of guidelines for electrical cable harnesses. Research showed that post-installation tests have been done since the Apollo era. For Ares I-X, the requirement for post-installation testing was removed to make it consistent with the avionics processes used on the Atlas V expendable launch vehicle. Further research for the report involved surveying government and private sector launch vehicle developers, military and commercial aircraft, spacecraft developers, and harness vendors. Responses indicated crewed launch vehicles and military aircraft perform post-installation tests. Key findings in the report were as follows: Test requirements identify damage, human-rated vehicles should be tested despite the identification of statistically few failures, data does not support the claim that post-installation testing damages the harness insulation system, and proper planning can reduce overhead associated with testing. The primary recommendation of the report is for the Ares projects to retain the practice of post-fabrication and post-installation cable harness testing.

  20. 43. Dressing rooms and corridor in basement on west side ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    43. Dressing rooms and corridor in basement on west side of building, looking south. (July 1991) A nearly identical corridor with dressing rooms ran along the east side of the basement, and the two corridors were connected by a short hallway at the north end. The theatre seats seen in hallway in this photo are from Seattle's Orpheum Theatre which was demolished in 1967. - Fox Theater, Seventh Avenue & Olive Way, Seattle, King County, WA

  1. Fault geometries in basement-induced wrench faulting under different initial stress states

    NASA Astrophysics Data System (ADS)

    Naylor, M. A.; Mandl, G.; Supesteijn, C. H. K.

    Scaled sandbox experiments were used to generate models for relative ages, dip, strike and three-dimensional shape of faults in basement-controlled wrench faulting. The basic fault sequence runs from early en échelon Riedel shears and splay faults through 'lower-angle' shears to P shears. The Riedel shears are concave upwards and define a tulip structure in cross-section. In three dimensions, each Riedel shear has a helicoidal form. The sequence of faults and three-dimensional geometry are rationalized in terms of the prevailing stress field and Coulomb-Mohr theory of shear failure. The stress state in the sedimentary overburden before wrenching begins has a substantial influence on the fault geometries and on the final complexity of the fault zone. With the maximum compressive stress (∂ 1) initially parallel to the basement fault (transtension), Riedel shears are only slightly en échelon, sub-parallel to the basement fault, steeply dipping with a reduced helicoidal aspect. Conversely, with ∂ 1 initially perpendicular to the basement fault (transpression), Riedel shears are strongly oblique to the basement fault strike, have lower dips and an exaggerated helicoidal form; the final fault zone is both wide and complex. We find good agreement between the models and both mechanical theory and natural examples of wrench faulting.

  2. 3D depth-to-basement and density contrast estimates using gravity and borehole data

    NASA Astrophysics Data System (ADS)

    Barbosa, V. C.; Martins, C. M.; Silva, J. B.

    2009-05-01

    We present a gravity inversion method for simultaneously estimating the 3D basement relief of a sedimentary basin and the parameters defining the parabolic decay of the density contrast with depth in a sedimentary pack assuming the prior knowledge about the basement depth at a few points. The sedimentary pack is approximated by a grid of 3D vertical prisms juxtaposed in both horizontal directions, x and y, of a right-handed coordinate system. The prisms' thicknesses represent the depths to the basement and are the parameters to be estimated from the gravity data. To produce stable depth-to-basement estimates we impose smoothness on the basement depths through minimization of the spatial derivatives of the parameters in the x and y directions. To estimate the parameters defining the parabolic decay of the density contrast with depth we mapped a functional containing prior information about the basement depths at a few points. We apply our method to synthetic data from a simulated complex 3D basement relief with two sedimentary sections having distinct parabolic laws describing the density contrast variation with depth. Our method retrieves the true parameters of the parabolic law of density contrast decay with depth and produces good estimates of the basement relief if the number and the distribution of boreholes are sufficient. We also applied our method to real gravity data from the onshore and part of the shallow offshore Almada Basin, on Brazil's northeastern coast. The estimated 3D Almada's basement shows geologic structures that cannot be easily inferred just from the inspection of the gravity anomaly. The estimated Almada relief presents steep borders evidencing the presence of gravity faults. Also, we note the existence of three terraces separating two local subbasins. These geologic features are consistent with Almada's geodynamic origin (the Mesozoic breakup of Gondwana and the opening of the South Atlantic Ocean) and they are important in understanding

  3. Flight performance, energetics and water turnover of tippler pigeons with a harness and dorsal load

    USGS Publications Warehouse

    Gessaman, J.A.; Workman, G.W.; Fuller, M.R.

    1991-01-01

    We measured carbon dioxide production and water efflux of 12 tippler pigeons (Columba spp.) during seven experimental flights using the doubly labeled water (DLW) method. Prior to the experiment birds were randomly assigned to one of two groups. One group flew as controls (no load or harness) on all seven flights. The other group wore a harness on two flights, a dorsal load/harness package (weighing about 5% of a bird's mass) on two flights, and they were without a load in three flights. Flight duration of pigeons with only a harness and with a dorsal load/harness package was 21 and 26% less, respectively, than the controls. Pigeons wearing a harness, or wearing a dorsal load/harness package lost water 50-90%, and 57-100% faster, respectively, than control pigeons. The mean CO2 production of pigeons wearing a harness or a load/harness package was not significantly different than pigeons without a harness or load. The small sample sizes and large variability in DLW measuremets precluded a good test of the energetic cost of flying with a harness and dorsal load.

  4. Flight performance energetics and water turnovers of Tippler Pigeons with a harness and doorsal load

    USGS Publications Warehouse

    Gessaman, James A.; Workman, Gar W.; Fuller, Mark R.

    1991-01-01

    We measured carbon dioxide production and water efflux of 12 tippler pigeons (Columba spp.) during seven experimental flights using the doubly labeled water (DLW) method. Prior to the experiment birds were randomly assigned to one of two groups. One group flew as controls (no load or harness) on all seven flights. The other group wore a harness on two flights, a dorsal load/harness package (weighing about 5% of a birda??s mass) on two flights, and they were without a load in three flights. Plight duration of pigeons with only a harness and with a dorsal load/harness package was 21 and 26% less, respectively, than the controls. Pigeons wearing a harness, or wearing a dorsal load/harness package lost water 50-90%, and 57-100% faster, respectively, than control pigeons. The mean CO, production of pigeons wearing a harness or a load/harness package was not significantly different than pigeons without a harness or load. The small sample sizes and large variability in DLW measurements precluded a good test of the energetic cost of flying with a harness and dorsal load.

  5. Effects of oxygen toxicity on cuprolinic blue-stained proteoglycans in alveolar basement membranes.

    PubMed

    Ferrara, T B; Fox, R B

    1992-02-01

    Effects of oxygen toxicity on distribution and density of proteoglycans in basement membranes of newborn rat lungs were assessed by electron microscopic analysis of tissues processed with cuprolinic blue, a cationic label that characteristically labels these anionically charged macromolecules. Newborn rats placed in greater than 95% oxygen at birth were killed at weekly intervals for 4 wk, and lung tissues fixed in 2.5% glutaraldehyde with 0.2% cuprolinic blue were processed for electron microscopy. Alveolar basement membranes from oxygen-treated and control animals were compared for differences in thickness and proteoglycan concentration and distribution. Results showed progressive thickening of alveolar basement membranes with increased duration of oxygen exposure. The normal distribution of proteoglycans, which is predominantly in the lamina rara externa of alveolar basement membranes, was frequently lost in thickened membranes found in oxygen-treated animals. Density of proteoglycans in these membranes decreased to 56% of normal by 2 wk of age and remained low with continued oxygen administration. Proteoglycan concentration in basement membranes on the interstitial side of alveolar capillaries in both control and oxygen-treated animals was low compared with proteoglycan concentration in basement membranes that opposed the alveolar air space, and administration of oxygen diminished these differences. These results demonstrate a direct alteration of proteoglycan distribution and density in the developing lung as a result of oxygen toxicity. This could result in decreased cell adhesion, influence the cellular response to lung injury, and contribute to the increased permeability seen with this disorder.

  6. Precambrian Basement Structure Map of the Continental United States - An Interpretation of Geologic and Aeromagnetic Data

    USGS Publications Warehouse

    Sims, Paul K.; Saltus, Richard W.; Anderson, Eric D.

    2008-01-01

    The Precambrian basement rocks of the continental United States are largely covered by younger sedimentary and volcanic rocks, and the availability of updated aeromagnetic data (NAMAG, 2002) provides a means to infer major regional basement structures and tie together the scattered, but locally abundant, geologic information. Precambrian basement structures in the continental United States have strongly influenced later Proterozoic and Phanerozoic tectonism within the continent, and there is a growing awareness of the utility of these structures in deciphering major younger tectonic and related episodes. Interest in the role of basement structures in the evolution of continents has been recently stimulated, particularly by publications of the Geological Society of London (Holdsworth and others, 1998; Holdsworth and others, 2001). These publications, as well as others, stress the importance of reactivation of basement structures in guiding the subsequent evolution of continents. Knowledge of basement structures is an important key to understanding the geology of continental interiors.

  7. 42 CFR 84.196 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Harnesses; installation and construction; minimum... SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Chemical Cartridge Respirators § 84.196 Harnesses; installation and construction; minimum...

  8. Impact of Harness Attachment Point on Kinetics and Kinematics During Sled Towing.

    PubMed

    Bentley, Ian; Atkins, Steve J; Edmundson, Christopher J; Metcalfe, John; Sinclair, Jonathan K

    2016-03-01

    Resisted sprint training is performed in a horizontal direction and involves similar muscles, velocities, and ranges of motion (ROM) to those of normal sprinting. Generally, sleds are attached to the athletes through a lead (3 m) and harness; the most common attachment points are the shoulder or waist. At present, it is not known how the different harness point's impact on the kinematics and kinetics associated with sled towing (ST). The aim of the current investigation was to examine the kinetics and kinematics of shoulder and waist harness attachment points in relation to the acceleration phase of ST. Fourteen trained men completed normal and ST trials, loaded at 10% reduction of sprint velocity. Sagittal plane kinematics from the trunk, hip, knee, and ankle were measured, together with stance phase kinetics (third footstrike). Kinetic and kinematic parameters were compared between harness attachments using one-way repeated-measures analysis of variance. The results indicated that various kinetic differences were present between the normal and ST conditions. Significantly greater net horizontal mean force, net horizontal impulses, propulsive mean force, and propulsive impulses were measured (p < 0.05). Interestingly, the waist harness also led to greater net horizontal impulse when compared with the shoulder attachment (p < 0.001). In kinematic terms, ST conditions significantly increased peak flexion in hip, knee, and ankle joints compared with the normal trials (p < 0.05). Results highlighted that the shoulder harness had a greater impact on trunk and knee joint kinematics when compared with the waist harness (p < 0.05). In summary, waist harnesses seem to be the most suitable attachment point for the acceleration phase of sprinting. Sled towing with these attachments resulted in fewer kinematic alterations and greater net horizontal impulse when compared with the shoulder harness. Future research is necessary in order to explore the long-term adaptations of

  9. Application of a modified harness design for attachment of radio transmitters to shorebirds

    USGS Publications Warehouse

    Sanzenbacher, Peter M.; Haig, Susan M.; Oring, Lewis W.

    2000-01-01

    Radio transmitter attachment methodology is important to the design of radio telemetry studies. In 1998, we attached 5 transmitters to a captive population of Western Sandpipers (Calidris mauri) and 7 transmitters to wild Killdeer (Charadriusv ociferus) using a modified version of the Rappole and Tipton (1991) figure-8 leg-loop harness. Captive birds fitted with harnesses did not exhibit quantifiable differences in behavior relative to control birds. Based on initial success in using the leg-loop harnesses, we used harnesses to attach transmitters in the wild to 30 Killdeer and 49 Dunlin (Calidris alpina) during the winters of 1998-1999 and 1999-2000. This was part of a study on movements of wintering shorebirds in the Willamette Valley of Oregon, USA. Wild birds showed no adverse effects of the harnesses.Thus, the described harness is a practical method for attachment of transmitters to shorebirds. Advantages of this harness method include a reduction in handling time at capture, elimination of the need to clip feathers for attachment, and increased transmitter retention time.

  10. 42 CFR 84.133 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Harnesses; installation and construction; minimum... SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Supplied-Air Respirators § 84.133 Harnesses; installation and construction; minimum requirements...

  11. Collective cell behavior on basement membranes floating in space

    NASA Astrophysics Data System (ADS)

    Ellison, Sarah; Bhattacharjee, Tapomoy; Morley, Cameron; Sawyer, W.; Angelini, Thomas

    The basement membrane is an essential part of the polarity of endothelial and epithelial tissues. In tissue culture and organ-on-chip devices, monolayer polarity can be established by coating flat surfaces with extracellular matrix proteins and tuning the trans-substrate permeability. In epithelial 3D culture, spheroids spontaneously establish inside-out polarity, morphing into hollow shell-like structures called acini, generating their own basement membrane on the inner radius of the shell. However, 3D culture approaches generally lack the high degree of control provided by the 2D culture plate or organ-on-chip devices, making it difficult to create more faithful in vitro tissue models with complex surface curvature and morphology. Here we present a method for 3D printing complex basement membranes covered in cells. We 3D print collagen-I and Matrigel into a 3D growth medium made from jammed microgels. This soft, yielding material allows extracellular matrix to be formed as complex surfaces and shapes, floating in space. We then distribute MCF10A epithelial cells across the polymerized surface. We envision employing this strategy to study 3D collective cell behavior in numerous model tissue layers, beyond this simple epithelial model.

  12. On-Orbit Evaluation of a New Treadmill Harness for Improved Crewmember Comfort and Load Distribution

    NASA Technical Reports Server (NTRS)

    Perusek, G. P.; Sheehan, C. C.; Savina, M. C.; Owings, T. M.; Davis, B. L.; Ryder, J. W.

    2011-01-01

    The current design of the International Space Station (ISS) Treadmill Harness has been reported to cause pain and discomfort to crewmembers during exercise. The Harness Station Development Test Objective (SDTO) provided participating crewmembers (n = 6) with a new harness design, the "Glenn Harness," to evaluate for comfort and loading as compared to the current Treadmill Harness. A novel suite of load-sensing instrumentation was developed to noninvasively measure load distribution and provided a first-ever quantification of actual dynamic loads during treadmill exercise. In addition, crew debriefs provided feedback on harness preference and overall impressions. Conclusions: Post-flight analysis in returned Glenn Harnesses (n = 3) showed minimal wear and tear. Four of the six subjects found the Glenn Harness to be more comfortable in this on-orbit, side-by-side comparison as measured by the crew comfort questionnaire and crew debriefs. Specific areas for improvement have been identified, and forward recommendations will be provided to the Human Research Program. The protocol developed for the SDTO provided valuable insight into crew comfort issues, design improvements, and loading preferences for exercise harnessing, which lays the groundwork for better harnessing systems and training protocols.

  13. Advances and limitations of visual conditioning protocols in harnessed bees.

    PubMed

    Avarguès-Weber, Aurore; Mota, Theo

    2016-10-01

    Bees are excellent invertebrate models for studying visual learning and memory mechanisms, because of their sophisticated visual system and impressive cognitive capacities associated with a relatively simple brain. Visual learning in free-flying bees has been traditionally studied using an operant conditioning paradigm. This well-established protocol, however, can hardly be combined with invasive procedures for studying the neurobiological basis of visual learning. Different efforts have been made to develop protocols in which harnessed honey bees could associate visual cues with reinforcement, though learning performances remain poorer than those obtained with free-flying animals. Especially in the last decade, the intention of improving visual learning performances of harnessed bees led many authors to adopt distinct visual conditioning protocols, altering parameters like harnessing method, nature and duration of visual stimulation, number of trials, inter-trial intervals, among others. As a result, the literature provides data hardly comparable and sometimes contradictory. In the present review, we provide an extensive analysis of the literature available on visual conditioning of harnessed bees, with special emphasis on the comparison of diverse conditioning parameters adopted by different authors. Together with this comparative overview, we discuss how these diverse conditioning parameters could modulate visual learning performances of harnessed bees. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. 33. VIEW OF BASEMENT UNDER EAST BOILER ROOM LOOKING TOWARD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    33. VIEW OF BASEMENT UNDER EAST BOILER ROOM LOOKING TOWARD WEST BOILER ROOM BASEMENT THROUGH THE ASH TRANSFER TUNNEL. ASH HOPPER FOR BOILER 900 IS ON THE RIGHT. NOTE THE TRACKS ALONG THE FLOOR OF THE TUNNEL. A SMALL ELECTRIC LOCOMOTIVE HAULED CARS FOR TRANSFERRING ASH FROM BOILERS TO DISPOSAL SITES OUTSIDE THE BUILDING. THIS SYSTEM BECAME OBSOLETE IN 1938 WHEN BOILERS IN THE WEST BOILER ROOM WERE REMOVED AND PULVERIZED COAL WAS ADOPTED AS THE FUEL. - New York, New Haven & Hartford Railroad, Cos Cob Power Plant, Sound Shore Drive, Greenwich, Fairfield County, CT

  15. Hopkins installs wire harnesses

    NASA Image and Video Library

    2013-11-24

    ISS038-E-008291 (24 Nov. 2013) --- NASA astronaut Michael Hopkins, Expedition 38 flight engineer, installs wire harnesses in the International Space Station?s Harmony node to support the installation of Ethernet video cables for the station?s local area network. These new cables will provide Ethernet connectivity to the visiting vehicles that dock to Harmony?s Earth-facing port.

  16. 14 CFR 91.521 - Shoulder harness.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... inertia load factors established under the certification basis of the airplane. (b) No person may operate... used; and (2) Safety belt and shoulder harness restraint systems may be designed to the inertia load...

  17. 14 CFR 91.521 - Shoulder harness.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... inertia load factors established under the certification basis of the airplane. (b) No person may operate... used; and (2) Safety belt and shoulder harness restraint systems may be designed to the inertia load...

  18. 14 CFR 91.521 - Shoulder harness.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... inertia load factors established under the certification basis of the airplane. (b) No person may operate... used; and (2) Safety belt and shoulder harness restraint systems may be designed to the inertia load...

  19. 14 CFR 91.521 - Shoulder harness.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... inertia load factors established under the certification basis of the airplane. (b) No person may operate... used; and (2) Safety belt and shoulder harness restraint systems may be designed to the inertia load...

  20. 14 CFR 91.521 - Shoulder harness.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... inertia load factors established under the certification basis of the airplane. (b) No person may operate... used; and (2) Safety belt and shoulder harness restraint systems may be designed to the inertia load...

  1. Structural and Geophysical Characterization of Oklahoma Basement

    NASA Astrophysics Data System (ADS)

    Morgan, C.; Johnston, C. S.; Carpenter, B. M.; Reches, Z.

    2017-12-01

    Oklahoma has experienced a large increase in seismicity since 2009 that has been attributed to wastewater injection. Most earthquakes, including four M5+ earthquakes, nucleated at depths > 4 km, well within the pre-Cambrian crystalline basement, even though wastewater injection occurred almost exclusively in the sedimentary sequence above. To better understand the structural characteristics of the rhyolite and granite that makeup the midcontinent basement, we analyzed a 150 m long core recovered from a basement borehole (Shads 4) in Rogers County, NE Oklahoma. The analysis of the fracture network in the rhyolite core included measurements of fracture inclination, aperture, and density, the examination fracture surface features and fill minerology, as well as x-ray diffraction analysis of secondary mineralization. We also analyzed the highly fractured and faulted segments of the core with a portable gamma-ray detector, magnetometer, and rebound hammer. The preliminary analysis of the fractures within the rhyolite core showed: (1) Fracture density increasing with depth by a factor of 10, from 4 fractures/10m in the upper core segment to 40 fracture/10m at 150 m deeper. (2) The fractures are primarily sub-vertical, inclined 10-20° from the axis of the vertical core. (3) The secondary mineralization is dominated by calcite and epidote. (4) Fracture aperture ranges from 0.35 to 2.35mm based on the thickness of secondary filling. (5) About 8% of the examined fractures display slickenside striations. (6) Increases of elasticity (by rebound hammer) and gamma-ray emissions are systematically correlated with a decrease in magnetic susceptibility in core segments of high fracture density and/or faulting; this observation suggests diagenetic fracture re-mineralization.

  2. Lumbar spine disc heights and curvature: upright posture vs. supine compression harness

    NASA Technical Reports Server (NTRS)

    Lee, Shi-Uk; Hargens, Alan R.; Fredericson, Michael; Lang, Philipp K.

    2003-01-01

    INTRODUCTION: Spinal lengthening in microgravity is thought to cause back pain in astronauts. A spinal compression harness can compress the spine to eliminate lengthening but the loading condition with harness is different than physiologic conditions. Our purpose was to compare the effect of spine compression with a harness in supine position on disk height and spinal curvature in the lumbar spine to that of upright position as measured using a vertically open magnetic resonance imaging system. METHODS: Fifteen healthy subjects volunteered. On day 1, each subject lay supine for an hour and a baseline scan of the lumbar spine was performed. After applying a load of fifty percent of body weight with the harness for thirty minutes, the lumbar spine was scanned again. On day 2, after a baseline scan, a follow up scan was performed after kneeling for thirty minutes within the gap between two vertically oriented magnetic coils. Anterior and posterior disk heights, posterior disk bulging, and spinal curvature were measured from the baseline and follow up scans. RESULTS: Anterior disk heights increased and posterior disk heights decreased compared with baseline scans both after spinal compression with harness and upright posture. The spinal curvature increased by both loading conditions of the spine. DISCUSSION: The spinal compression with specially designed harness has the same effect as the physiologic loading of the spine in the kneeling upright position. The harness shows some promise as a tool to increase the diagnostic capabilities of a conventional MR system.

  3. Basement radon entry and stack driven moisture infiltration reduced by active soil depressurization

    Treesearch

    C.R. Boardman; Samuel V. Glass

    2015-01-01

    This case study presents measurements of radon and moisture infiltration from soil gases into the basement of an unoccupied research house in Madison, Wisconsin, over two full years. The basement floor and exterior walls were constructed with preservative-treated lumber and plywood. In addition to continuous radon monitoring, measurements included building air...

  4. 14. View toward the northwest corner of the basement in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. View toward the northwest corner of the basement in the north segment of the building. Portions of the basement floor are earth, and portions are concrete. For some undetermined reason an unbonded, narrow panel of brick occurs in the west (left) wall. A corbeled brick footing is seen under this panel, as if the panel is carrying a concentrated load. An identical element occurs to the left, outside the camera's view. These 'columns' may support the second-story brick facade over the ground floor store windows. Credit GADA/MRM. - Stroud Building, 31-33 North Central Avenue, Phoenix, Maricopa County, AZ

  5. Indoors and health: results of a systematic literature review assessing the potential health effects of living in basements.

    PubMed

    Mezzoiuso, Angelo Giosué; Gola, Marco; Rebecchi, Andrea; Riccò, Matteo; Capolongo, Stefano; Buffoli, Maddalena; Tirani, Marcello; Odone, Anna; Signorelli, Carlo

    2017-10-23

    A new law approved in March 2017 in the Lombardy Region makes it possible to live in basements. Basements are defined as buildings partly below curb level but with at least one-half of its height above the curb. Basements' features and structural characteristics might pose risks to human health. In this paper we adopt a multidisciplinary approach to assess the potential health effects of living in basements. In particular, we define a conceptual framework to describe basements' structural characteristics which are risk factors, as well as the mechanisms through which they impact on human health. We also conduct a systematic review on the scientific databases PubMed,Embase, DOAJ, Proquest and EBSCO to retrieve, pool and critically analyze all available research that quantified the risk of living in basements for different health outcomes. Available evidence suggests living in basements increases the risk of respiratory diseases (asthma and allergic disorders); more heterogeneous data are available for cancers and cardiovascular diseases. As more quantitative data need to be prospectively retrieved to assess and monitor the risk of living in basements for human health, clear minimum requirements for light, air, sanitation and egress are to be defined by technical experts and enforced by policy makers.

  6. Harnessing Technology to Support Learning

    ERIC Educational Resources Information Center

    Richardson, Tony; Ecclesfield, Nigel; Lewis, Christine

    2008-01-01

    In April 2008, one sees the start of the consultation on the second phase of the government's e-strategy for education, published in 2005 as "Harnessing technology: transforming learning and children's services." This follows hard on the heels of the progress report and implementation plan for the technology strategy for further…

  7. Volcanic conduit migration over a basement landslide at Mount Etna (Italy).

    PubMed

    Nicolosi, I; Caracciolo, F D'Ajello; Branca, S; Ventura, G; Chiappini, M

    2014-06-13

    The flanks of volcanoes may slide in response to the loading of the edifice on a weak basement, magma push, and/or to tectonic stress. However, examples of stratovolcanoes emplaced on active landslides are lacking and the possible effects on the volcano dynamics unknown. Here, we use aeromagnetic data to construct a three-dimensional model of the clay-rich basement of Etna volcano (Italy). We provide evidence for a large stratovolcano growing on a pre-existing basement landslide and show that the eastern Etna flank, which slides toward the sea irrespective of volcanic activity, moves coherently with the underlying landslide. The filling of the landslide depression by lava flows through time allows the formation of a stiffness barrier, which is responsible for the long-term migration of the magma pathways from the coast to the present-day Etna summit. These unexpected results provide a new interpretation clue on the causes of the volcanic instability processes and of the mechanisms of deflection and migration of volcanic conduits.

  8. Basement geology of the National Petroleum Reserve Alaska (NPRA), Northern Alaska

    USGS Publications Warehouse

    Saltus, R.W.; Hudson, T.L.; Phillips, J.D.; Kulander, C.; Dumoulin, Julie A.; Potter, C.

    2002-01-01

    Gravity, aeromagnetic, seismic, and borehole information enable mapping of crustal basement characteristics within the National Petroleum Reserve Alaska (NPRA). In general, the pre-Mississippian basement of the southern portion of the NPRA is different from that in the north in that it is deeper and thinner, is made up of dense magnetic rocks, is cut by more normal faults, and underlies thicker accumulations of Mississippian to Triassic Ellesmerian sequence sedimentary rocks. Mafic igneous rocks within the basement and locally within the deeper Ellesmerian sequence sedimentary section could explain the observed density and magnetic variations. Because these variations spatially overlap thicker Ellesmerian sequence sediment accumulations, they may have developed, at least in part, during Mississippian to Triassic extension and basin formation. If this period of extension, and postulated mafic magmatism, was accompanied by higher heat flow, then early Ellesmerian sequence clastic sediments may have become mature for hydrocarbon generation (Magoon and Bird, 1988). This could have produced an early petroleum system in the Colville basin.

  9. Sedimentation History and Provenance Analysis of a Late Mesozoic Rifting Event at Tavan Har, East Gobi, Mongolia

    ERIC Educational Resources Information Center

    Davidson, Sarah Cain

    2005-01-01

    The East Gobi Basin (EGB), which covers over 1.5 million square kilometers in southeastern Mongolia, is one of several basins in eastern China and Mongolia that was formed by extension and intracontinental rifting during the late Mesozoic. For reasons that are poorly understood, the continental lithosphere covering areas that are now known as…

  10. Integration of a Copper-Containing Biohybrid (CuHARS) with Cellulose for Subsequent Degradation and Biomedical Control

    PubMed Central

    Karan, Anik; Darder, Margarita; Kansakar, Urna; Norcross, Zach

    2018-01-01

    We previously described the novel synthesis of a copper high-aspect ratio structure (CuHARS) biohybrid material using cystine. While extremely stable in water, CuHARS is completely (but slowly) degradable in cellular media. Here, integration of the CuHARS into cellulose matrices was carried out to provide added control for CuHARS degradation. Synthesized CuHARS was concentrated by centrifugation and then dried. The weighed mass was re-suspended in water. CuHARS was stable in water for months without degradation. In contrast, 25 μg/mL of the CuHARS in complete cell culture media was completely degraded (slowly) in 18 days under physiological conditions. Stable integration of CuHARS into cellulose matrices was achieved through assembly by mixing cellulose micro- and nano-fibers and CuHARS in an aqueous (pulp mixture) phase, followed by drying. Additional materials were integrated to make the hybrids magnetically susceptible. The cellulose-CuHARS composite films could be transferred, weighed, and cut into usable pieces; they maintained their form after rehydration in water for at least 7 days and were compatible with cell culture studies using brain tumor (glioma) cells. These studies demonstrate utility of a CuHARS-cellulose biohybrid for applied applications including: (1) a platform for biomedical tracking and (2) integration into a 2D/3D matrix using natural products (cellulose). PMID:29693569

  11. Which is the better forecasting model? A comparison between HAR-RV and multifractality volatility

    NASA Astrophysics Data System (ADS)

    Ma, Feng; Wei, Yu; Huang, Dengshi; Chen, Yixiang

    2014-07-01

    In this paper, by taking the 5-min high frequency data of the Shanghai Composite Index as example, we compare the forecasting performance of HAR-RV and Multifractal volatility, Realized volatility, Realized Bipower Variation and their corresponding short memory model with rolling windows forecasting method and the Model Confidence Set which is proved superior to SPA test. The empirical results show that, for six loss functions, HAR-RV outperforms other models. Moreover, to make the conclusions more precise and robust, we use the MCS test to compare the performance of their logarithms form models, and find that the HAR-log(RV) has a better performance in predicting future volatility. Furthermore, by comparing the two models of HAR-RV and HAR-log(RV), we conclude that, in terms of performance forecasting, the HAR-log(RV) model is the best model among models we have discussed in this paper.

  12. The zebrafish dystrophic mutant softy maintains muscle fibre viability despite basement membrane rupture and muscle detachment

    PubMed Central

    Jacoby, Arie S.; Busch-Nentwich, Elisabeth; Bryson-Richardson, Robert J.; Hall, Thomas E.; Berger, Joachim; Berger, Silke; Sonntag, Carmen; Sachs, Caroline; Geisler, Robert; Stemple, Derek L.; Currie, Peter D.

    2009-01-01

    Summary The skeletal muscle basement membrane fulfils several crucial functions during development and in the mature myotome and defects in its composition underlie certain forms of muscular dystrophy. A major component of this extracellular structure is the laminin polymer, which assembles into a resilient meshwork that protects the sarcolemma during contraction. Here we describe a zebrafish mutant, softy, which displays severe embryonic muscle degeneration as a result of initial basement membrane failure. The softy phenotype is caused by a mutation in the lamb2 gene, identifying laminin β2 as an essential component of this basement membrane. Uniquely, softy homozygotes are able to recover and survive to adulthood despite the loss of myofibre adhesion. We identify the formation of ectopic, stable basement membrane attachments as a novel means by which detached fibres are able to maintain viability. This demonstration of a muscular dystrophy model possessing innate fibre viability following muscle detachment suggests basement membrane augmentation as a therapeutic strategy to inhibit myofibre loss. PMID:19736328

  13. Damping Models for Shear-Deformable Beam with Applications to Spacecraft Wiring Harness

    DTIC Science & Technology

    2014-10-28

    AFRL-RV-PS- TR-2014-0189 AFRL-RV-PS- TR-2014-0189 DAMPING MODELS FOR SHEAR-DEFORMABLE BEAM WITH APPLICATIONS TO SPACECRAFT WIRING HARNESS ...Feb 2012 4. TITLE AND SUBTITLE Damping Models for Shear-Deformable Beam with Applications to Spacecraft Wiring Harness 5a. CONTRACT NUMBER FA9453-12...behavior of wiring harnesses . The emphasis in this project will be on the extension of the shear-beam damping model to the Timoshenko beam, a beam model

  14. Harnessing our very life.

    PubMed

    Wills, Peter R; Williams, David L F; Trussell, Denys; Mann, L R B

    2013-01-01

    The Aristotelian ideas of nature (physis) and technology (techné) are taken as a starting point for understanding what it would mean for technology to be truly living. Heidegger's critique of the conflation of scientific and technological thinking in the current era is accepted as demonstrating that humanity does not have a deep enough appreciation of the nature of life to harness its essence safely. Could the vision of harnessing life be realized, which we strongly doubt, living technology would give selected humans transforming powers that could be expected to exacerbate, rather than solve, current global problems. The source of human purposefulness, and hence of both technology and ethics, is identified in nature's emergent capability to instantiate informational representations in material forms. Ethics that are properly grounded in an appreciation of intrinsic value, especially that of life, demand that proposals to give humanity the capabilities of living technology address the social, political, economic, and environmental problems inherent in its development and potential deployment. Before any development is embarked on, steps must be taken to avoid living technology, whatever the term eventually designates, becoming available for destructive or antisocial purposes such as those that might devastate humanity or irrevocably damage the natural world.

  15. Harness the Power of Technology

    ERIC Educational Resources Information Center

    Duncan, Arne

    2011-01-01

    Today, U.S. educators are teaching in the midst of a technological revolution. Technology promises to provide innovative solutions in the nation's classrooms, just as it has transformed the way people communicate, socialize, and conduct business. In this article, the author argues that now is the time to harness technology to revolutionize the way…

  16. Transmission Electron Microscopy Analysis of Epithelial Basement Membrane Repair in Rabbit Corneas With Haze

    PubMed Central

    Torricelli, Andre A. M.; Singh, Vivek; Agrawal, Vandana; Santhiago, Marcony R.; Wilson, Steven E.

    2013-01-01

    Purpose. To assess the ultrastructure of the epithelial basement membrane using transmission electron microscopy (TEM) in rabbit corneas with and without subepithelial stroma opacity (haze). Methods. Two groups of eight rabbits each were included in this study. Photorefractive keratectomy (PRK) was performed using an excimer laser. The first group had −4.5-diopter (−4.5D) PRK and the second group had −9.0D PRK. Contralateral eyes were unwounded controls. Rabbits were sacrificed at 4 weeks after surgery. Immunohistochemical analysis was performed to detect the myofibroblast marker α-smooth muscle actin (SMA). TEM was performed to analyze the ultrastructure of the epithelial basement membrane and stroma. Results. At 4 weeks after PRK, α-SMA+ myofibroblasts were present at high density in the subepithelial stroma of rabbit eyes that had −9.0D PRK, along with prominent disorganized extracellular matrix, whereas few myofibroblasts and little disorganized extracellular matrix were noted in eyes that had −4.5D PRK. The epithelial basement membrane was irregular and discontinuous and lacking typical morphology in all corneas at 1 month after −9D PRK compared to corneas at 1 month in the −4.5D PRK group. Conclusions. The epithelial basement membrane acts as a critical modulator of corneal wound healing. Structural and functional defects in the epithelial basement membrane correlate to both stromal myofibroblast development from precursor cells and continued myofibroblast viability, likely through the modulation of epithelial–stromal interactions mediated by cytokines. Prolonged stromal haze in the cornea is associated with abnormal regeneration of the epithelial basement membrane. PMID:23696606

  17. Characterizing nanoscale topography of the aortic heart valve basement membrane for tissue engineering heart valve scaffold design.

    PubMed

    Brody, Sarah; Anilkumar, Thapasimuthu; Liliensiek, Sara; Last, Julie A; Murphy, Christopher J; Pandit, Abhay

    2006-02-01

    A fully effective prosthetic heart valve has not yet been developed. A successful tissue-engineered valve prosthetic must contain a scaffold that fully supports valve endothelial cell function. Recently, topographic features of scaffolds have been shown to influence the behavior of a variety of cell types and should be considered in rational scaffold design and fabrication. The basement membrane of the aortic valve endothelium provides important parameters for tissue engineering scaffold design. This study presents a quantitative characterization of the topographic features of the native aortic valve endothelial basement membrane; topographical features were measured, and quantitative data were generated using scanning electron microscopy (SEM), atomic force microscopy (AFM), transmission electron microscopy (TEM), and light microscopy. Optimal conditions for basement membrane isolation were established. Histological, immunohistochemical, and TEM analyses following decellularization confirmed basement membrane integrity. SEM and AFM photomicrographs of isolated basement membrane were captured and quantitatively analyzed. The basement membrane of the aortic valve has a rich, felt-like, 3-D nanoscale topography, consisting of pores, fibers, and elevations. All features measured were in the sub-100 nm range. No statistical difference was found between the fibrosal and ventricular surfaces of the cusp. These data provide a rational starting point for the design of extracellular scaffolds with nanoscale topographic features that mimic those found in the native aortic heart valve basement membrane.

  18. Characterizing Nanoscale Topography of the Aortic Heart Valve Basement Membrane for Tissue Engineering Heart Valve Scaffold Design

    PubMed Central

    BRODY, SARAH; ANILKUMAR, THAPASIMUTHU; LILIENSIEK, SARA; LAST, JULIE A.; MURPHY, CHRISTOPHER J.; PANDIT, ABHAY

    2016-01-01

    A fully effective prosthetic heart valve has not yet been developed. A successful tissue-engineered valve prosthetic must contain a scaffold that fully supports valve endothelial cell function. Recently, topographic features of scaffolds have been shown to influence the behavior of a variety of cell types and should be considered in rational scaffold design and fabrication. The basement membrane of the aortic valve endothelium provides important parameters for tissue engineering scaffold design. This study presents a quantitative characterization of the topographic features of the native aortic valve endothelial basement membrane; topographical features were measured, and quantitative data were generated using scanning electron microscopy (SEM), atomic force microscopy (AFM), transmission electron microscopy (TEM), and light microscopy. Optimal conditions for basement membrane isolation were established. Histological, immunohistochemical, and TEM analyses following decellularization confirmed basement membrane integrity. SEM and AFM photomicrographs of isolated basement membrane were captured and quantitatively analyzed. The basement membrane of the aortic valve has a rich, felt-like, 3-D nanoscale topography, consisting of pores, fibers, and elevations. All features measured were in the sub-100 nm range. No statistical difference was found between the fibrosal and ventricular surfaces of the cusp. These data provide a rational starting point for the design of extracellular scaffolds with nanoscale topographic features that mimic those found in the native aortic heart valve basement membrane. PMID:16548699

  19. Manufacturing and quality control of interconnecting wire harnesses, Volume 4

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The document covers interconnecting wire harnesses defined in the design standard, including type 8, flat conductor cable. Volume breadth covers installations of groups of harnesses in a major assembly and the associated post installation inspections and electrical tests. Knowledge gained through experience on the Saturn 5 program coupled with recent advances in techniques, materials, and processes was incorporated into this document.

  20. Vascular basement membranes as pathways for the passage of fluid into and out of the brain.

    PubMed

    Morris, Alan W J; Sharp, Matthew MacGregor; Albargothy, Nazira J; Fernandes, Rute; Hawkes, Cheryl A; Verma, Ajay; Weller, Roy O; Carare, Roxana O

    2016-05-01

    In the absence of conventional lymphatics, drainage of interstitial fluid and solutes from the brain parenchyma to cervical lymph nodes is along basement membranes in the walls of cerebral capillaries and tunica media of arteries. Perivascular pathways are also involved in the entry of CSF into the brain by the convective influx/glymphatic system. The objective of this study is to differentiate the cerebral vascular basement membrane pathways by which fluid passes out of the brain from the pathway by which CSF enters the brain. Experiment 1: 0.5 µl of soluble biotinylated or fluorescent Aβ, or 1 µl 15 nm gold nanoparticles was injected into the mouse hippocampus and their distributions determined at 5 min by transmission electron microscopy. Aβ was distributed within the extracellular spaces of the hippocampus and within basement membranes of capillaries and tunica media of arteries. Nanoparticles did not enter capillary basement membranes from the extracellular spaces. Experiment 2: 2 µl of 15 nm nanoparticles were injected into mouse CSF. Within 5 min, groups of nanoparticles were present in the pial-glial basement membrane on the outer aspect of cortical arteries between the investing layer of pia mater and the glia limitans. The results of this study and previous research suggest that cerebral vascular basement membranes form the pathways by which fluid passes into and out of the brain but that different basement membrane layers are involved. The significance of these findings for neuroimmunology, Alzheimer's disease, drug delivery to the brain and the concept of the Virchow-Robin space are discussed.

  1. Volcanic conduit migration over a basement landslide at Mount Etna (Italy)

    PubMed Central

    Nicolosi, I.; Caracciolo, F. D'Ajello; Branca, S.; Ventura, G.; Chiappini, M.

    2014-01-01

    The flanks of volcanoes may slide in response to the loading of the edifice on a weak basement, magma push, and/or to tectonic stress. However, examples of stratovolcanoes emplaced on active landslides are lacking and the possible effects on the volcano dynamics unknown. Here, we use aeromagnetic data to construct a three-dimensional model of the clay-rich basement of Etna volcano (Italy). We provide evidence for a large stratovolcano growing on a pre-existing basement landslide and show that the eastern Etna flank, which slides toward the sea irrespective of volcanic activity, moves coherently with the underlying landslide. The filling of the landslide depression by lava flows through time allows the formation of a stiffness barrier, which is responsible for the long-term migration of the magma pathways from the coast to the present-day Etna summit. These unexpected results provide a new interpretation clue on the causes of the volcanic instability processes and of the mechanisms of deflection and migration of volcanic conduits. PMID:24924784

  2. 14 CFR 91.107 - Use of safety belts, shoulder harnesses, and child restraint systems.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Use of safety belts, shoulder harnesses... OPERATING AND FLIGHT RULES Flight Rules General § 91.107 Use of safety belts, shoulder harnesses, and child... fasten and unfasten that person's safety belt and, if installed, shoulder harness. (2) No pilot may cause...

  3. 14 CFR 135.171 - Shoulder harness installation at flight crewmember stations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Shoulder harness installation at flight... ON BOARD SUCH AIRCRAFT Aircraft and Equipment § 135.171 Shoulder harness installation at flight... configuration, excluding any pilot seat, of 10 seats or more unless it is equipped with an approved shoulder...

  4. 14 CFR 135.171 - Shoulder harness installation at flight crewmember stations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Shoulder harness installation at flight... ON BOARD SUCH AIRCRAFT Aircraft and Equipment § 135.171 Shoulder harness installation at flight... configuration, excluding any pilot seat, of 10 seats or more unless it is equipped with an approved shoulder...

  5. 14 CFR 135.171 - Shoulder harness installation at flight crewmember stations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Shoulder harness installation at flight... ON BOARD SUCH AIRCRAFT Aircraft and Equipment § 135.171 Shoulder harness installation at flight... configuration, excluding any pilot seat, of 10 seats or more unless it is equipped with an approved shoulder...

  6. 14 CFR 135.171 - Shoulder harness installation at flight crewmember stations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Shoulder harness installation at flight... ON BOARD SUCH AIRCRAFT Aircraft and Equipment § 135.171 Shoulder harness installation at flight... configuration, excluding any pilot seat, of 10 seats or more unless it is equipped with an approved shoulder...

  7. 14 CFR 135.171 - Shoulder harness installation at flight crewmember stations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Shoulder harness installation at flight... ON BOARD SUCH AIRCRAFT Aircraft and Equipment § 135.171 Shoulder harness installation at flight... configuration, excluding any pilot seat, of 10 seats or more unless it is equipped with an approved shoulder...

  8. Integrating Reflection Seismic, Gravity and Magnetic Data to Reveal the Structure of Crystalline Basement: Implications for Understanding Rift Development

    NASA Astrophysics Data System (ADS)

    Lenhart, Antje; Jackson, Christopher A.-L.; Bell, Rebecca E.; Duffy, Oliver B.; Fossen, Haakon; Gawthorpe, Robert L.

    2016-04-01

    Numerous rifts form above crystalline basement containing pervasive faults and shear zones. However, the compositional and mechanical heterogeneity within crystalline basement and the geometry and kinematics of discrete and pervasive basement fabrics are poorly understood. Furthermore, the interpretation of intra-crustal structures beneath sedimentary basins is often complicated by limitations in the depth of conventional seismic imaging, the commonly acoustically transparent nature of basement, limited well penetrations, and complex overprinting of multiple tectonic events. Yet, a detailed knowledge of the structural and lithological complexity of crystalline basement rocks is crucial to improve our understanding of how rifts evolve. Potential field methods are a powerful but perhaps underutilised regional tool that can decrease interpretational uncertainty based solely on seismic reflection data. We use petrophysical data, high-resolution 3D reflection seismic volumes, gridded gravity and magnetic data, and 2D gravity and magnetic modelling to constrain the structure of crystalline basement offshore western Norway. Intra-basement structures are well-imaged on seismic data due to relatively shallow burial of the basement beneath a thin (<3.5 km) sedimentary cover. Variations in basement composition were interpreted from detailed seismic facies analysis and mapping of discrete intra-basement reflections. A variety of data filtering and isolation techniques were applied to the original gravity and magnetic data in order to enhance small-scale field variations, to accentuate formation boundaries and discrete linear trends, and to isolate shallow and deep crustal anomalies. In addition, 2D gravity and magnetic data modelling was used to verify the seismic interpretation and to further constrain the configuration of the upper and lower crust. Our analysis shows that the basement offshore western Norway is predominantly composed of Caledonian allochthonous nappes

  9. Basement structure of the United Arab Emirates derived from an analysis of regional gravity and aeromagnetic database

    NASA Astrophysics Data System (ADS)

    Ali, M. Y.; Fairhead, J. D.; Green, C. M.; Noufal, A.

    2017-08-01

    Gravity and aeromagnetic data covering the whole territory of the United Arab Emirates (UAE) have been used to evaluate both shallow and deep geological structures, in particular the depth to basement since it is not imaged by seismic data anywhere within the UAE. Thus, the aim has been to map the basement so that its structure can help to assess its control on the distribution of hydrocarbons within the UAE. Power spectrum analysis reveals gravity and magnetic signatures to have some similarities, in having two main density/susceptibility interfaces widely separated in depth such that regional-residual anomaly separation could effectively be undertaken. The upper density/susceptibility interface occurs at a depth of about 1.0 km while the deeper interface varies in depth throughout the UAE. For gravity, this deeper interface is assumed to be due to the combined effect of lateral changes in density structures within the sediments and in depth of basement while for magnetics it is assumed the sediments have negligible susceptibility and the anomalies unrelated to the volcanic/magmatic bodies result from only changes in depth to basement. The power spectrum analysis over the suspect volcanic/magmatic bodies indicates they occur at 5 km depth. The finite tilt-depth and finite local wavenumber methods were used to estimate depth to source and only depths that agree to within 10% of each other were used to generate the depth to basement map. This depth to basement map, to the west of the UAE-Oman Mountains, varies in depth from 5 km to in excess of 15 km depth and is able to structurally account for the location of the shear structures, seen in the residual magnetic data, and the location of the volcanic/magmatic centres relative to a set of elongate N-S to NE-SW trending basement highs. The majority of oilfields in the UAE are located within these basement highs. Therefore, the hydrocarbon distribution in the UAE basin appears to be controlled by the location of the

  10. The benefits of the use of shoulder harness in general aviation aircraft.

    DOT National Transportation Integrated Search

    1972-02-01

    The installation and use of shoulder harnesses is a practical and relatively inexpensive solution to the problem of maintaining separation between man and machine during an aircraft crash sequence. The addition of shoulder harness to the tiedown chai...

  11. Application of high resolution aeromagnetic data for basement topography mapping of Siluko and environs, southwestern Nigeria

    NASA Astrophysics Data System (ADS)

    Osinowo, Olawale O.; Akanji, Adesoji O.; Olayinka, Abel I.

    2014-11-01

    The discovery of hydrocarbon in commercial quantity in the Niger Delta, southern Nigeria, has since the early fifties shifted the attention of exploration/active geological studies from the Dahomey basin and the adjacent basement terrain in south-western Nigeria towards the south and this has left some gaps in information required for the discovery and exploitation of the economic potential of the region. This study mapped the Siluko transition zone in south-western Nigeria in terms of structures, geometry and basement topography with the object of providing requisite geological information that will engender interest in the exploration and exploitation of the numerous economic potentials of south-western part of Nigeria. Acquired high resolution aeromagnetic data were filtered, processed and enhanced, the resultant data were subjected to qualitative and quantitative magnetic interpretation, depth weighting analyses and modelling to generate the subsurface basement topography across the study area. The obtained results indicate regions of high and low magnetic anomalies with residual magnetic intensity values ranging from -100.8 nT to 100.9 nT. Euler Deconvolution indicates generally undulating basement topography with depth range of 125-1812 m. The basement relief is generally gentle and flat lying within the basement terrain with depth ranging from 125 to 500 m. However the sedimentary terrain is undulating and generally steeps south, down the basin with depth range of 300-1812 m. A basement topography model of the magnetic data constrained by Euler solutions correlate positively with the geology of the study area and indicates a generally increasing sedimentary deposits' thickness southward toward the western part of Dahomey basin. The revealed basement topography and structures as well as the delineated direction of continuous increase in thickness of sedimentary deposit provide insight to the controlling factor responsible for tar sand deposit and bitumen

  12. 4. BASEMENT WALL BENEATH SOUTH PASSAGE SHOWING STEAM TUNNEL OPENING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. BASEMENT WALL BENEATH SOUTH PASSAGE SHOWING STEAM TUNNEL OPENING IN SOUTH WALL. - Pennsylvania Railroad Station, South Baggage Passage & Canopy, 1101 Liberty Avenue, Pittsburgh, Allegheny County, PA

  13. 7. Details of northeast elevation, demonstrating the relationship of basement ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Details of northeast elevation, demonstrating the relationship of basement windows to column bases. - Roanoke Veterans Administration Hospital, Building No. 6, 1970 Roanoke Boulevard, Salem, Salem, VA

  14. Interior detail of basement door, woodenlouvered transom and glass doorknob, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior detail of basement door, wooden-louvered transom and glass doorknob, facing southeast. - Gorgas Hospital, Administration & Clinics Building, Culebra Road, Balboa Heights, Former Panama Canal Zone, CZ

  15. Basement characterization and crustal structure beneath the Arabia-Eurasia collision (Iran): A combined gravity and magnetic study

    NASA Astrophysics Data System (ADS)

    Mousavi, Naeim; Ebbing, Jörg

    2018-04-01

    We present a study on the depth to basement and magnetic crustal domains beneath the Iranian Plateau by modeling aeromagnetic and gravity data. First, field processing of the aeromagnetic data was undertaken to estimate the general characteristics of the magnetic basement. Afterwards, inverse modeling of aeromagnetic data was carried out to estimate the depth to basement. The obtained model of basement was refined using combined gravity and magnetic forward modeling. Hereby, we were able to distinguish different magnetic domains in the uppermost crust (10-20 km depths) influencing the medium to long wavelength trends of the magnetic anomalies. Magnetic basement mapping shows that prominent shallow magnetic features are furthermore located in the volcanic areas, e.g. the Urumieh Dokhtar Magmatic Assemblage. The presence of ophiolite outcrops in SE Iran implies that shallow oceanic crust (with high magnetization) is the main source of one of the biggest magnetic anomalies in entire Iran area located north of the Makran.

  16. Basement-driven strike-slip deformation involving a salt-stock canopy system

    NASA Astrophysics Data System (ADS)

    Dooley, Tim; Jackson, Martin; Hudec, Mike

    2016-04-01

    NW-striking basement-involved strike-slip zones have been reported or inferred from the northern Gulf of Mexico (GoM). This interpretation is uncertain, because the effects of strike-slip deformation are commonly difficult to recognize in cross sections. Recognition is doubly difficult if the strike-slip zone passes through a diapir field that complicates deformation, and an associated salt canopy that partially decouples shallow deformation from deep deformation. We use physical models to explore the effects of strike-slip deformation above and below a salt-stock canopy system. Canopies of varying maturity grew from a series of 14 feeders/diapirs located on and off the axis of a dextral basement fault. Strike-slip deformation styles in the overburden vary significantly depending on: (1) the location of the diapirs with respect to the basement fault trace, and; (2) the continuity of the canopy system. On-axis diapirs (where the diapirs lie directly above the basement fault) are typically strongly deformed and pinched shut at depth to form sharp S-shapes, whereas their shallow deformation style is that of a open-S-shaped pop-up structure in a restraining bend. The narrow diapir stem acts as a shear zone at depth. Pull-apart structures form between diapirs that are arranged in a right-stepping array tangental to the basement fault trace. These grade along strike into narrow negative flower structures. Off-axis diapirs (diapirs laterally offset from the basement fault but close enough to participate in the deformation) form zones of distributed deformation in the form of arrays of oblique faults (R shears) that converge along strike onto the narrower deformation zones associated with on-axis diapirs. Above an immature, or patchy, canopy system the strike-slip structures closely match sub canopy structures, with the exception of wrench fold formation where the supracanopy roof is thin. In contrast, the surface structures above a mature canopy system consist of a broad

  17. A Case of Alport Syndrome with Posttransplant Antiglomerular Basement Membrane Disease despite Negative Antiglomerular Basement Membrane Antibodies by EIA Treated with Plasmapheresis and Intravenous Immunoglobulin.

    PubMed

    Armstead, Sumiko I; Hellmark, Thomas; Wieslander, Jorgen; Zhou, Xin J; Saxena, Ramesh; Rajora, Nilum

    2013-01-01

    Posttransplant antiglomerular basement membrane (anti-GBM) disease occurs in approximately 5% of Alport patients and usually ends in irreversible graft failure. Recent research has focused on characterizing the structure of the anti-GBM alloepitope. Here we present a case of a 22-year-old male with end-stage renal disease secondary to Alport syndrome, with a previously failed renal allograft, who received a second deceased-donor kidney transplant. Six days after transplantation, he developed acute kidney injury. The serum anti-GBM IgG was negative by enzyme immunoassay (EIA). On biopsy, he had crescentic glomerulonephritis with linear GBM fixation of IgG. With further analysis by western blotting, we were able to detect antibodies to an unidentified protein from the basement membrane. This patient was treated with plasmapheresis twice per week and monthly intravenous immunoglobulin (IVIG) for a total of five months. At the end of treatment, these unknown antibodies were no longer detected. His renal function improved, and he has not required dialysis. We conclude that anti-GBM disease in patients with Alport Syndrome may be caused by circulating antibodies to other components of the basement membrane that are undetectable by routine anti-GBM EIA and may respond to treatment with plasmapheresis and IVIG.

  18. Isotropic Versus Bipolar Functionalized Biomimetic Artificial Basement Membranes and Their Evaluation in Long-Term Human Cell Co-Culture.

    PubMed

    Rossi, Angela; Wistlich, Laura; Heffels, Karl-Heinz; Walles, Heike; Groll, Jürgen

    2016-08-01

    In addition to dividing tissues into compartments, basement membranes are crucial as cell substrates and to regulate cellular behavior. The development of artificial basement membranes is indispensable for the ultimate formation of functional engineered tissues; however, pose a challenge due to their complex structure. Herein, biodegradable electrospun polyester meshes are presented, exhibiting isotropic or bipolar bioactivation as a biomimetic and biofunctional model of the natural basement membrane. In a one-step preparation process, reactive star-shaped prepolymer additives, which generate a hydrophilic fiber surface, are electrospun with cell-adhesion-mediating peptides, derived from major components of the basement membrane. Human skin cells adhere to the functionalized meshes, and long-term co-culture experiments confirm that the artificial basement membranes recapitulate and preserve tissue specific functions. Several layers of immortalized human keratinocytes grow on the membranes, differentiating toward the surface and expressing typical epithelial markers. Fibroblasts migrate into the reticular lamina mimicking part of the mesh. Both cells types begin to produce extracellular matrix proteins and to remodel the initial membrane. It is shown at the example of skin that the artificial basement membrane design provokes biomimetic responses of different cell types and can thus be used as basis for the future development of basement membrane containing tissues. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. A Nonlinear Inversion Approach to Map the Magnetic Basement: A Case Study from Central India Using Aeromagnetic Data

    NASA Astrophysics Data System (ADS)

    Kumar, R.; Bansal, A. R.; Anand, S. P.; Rao, V. K.; Singh, U. K.

    2016-12-01

    The central India region is having complex geology covering various geological units e.g., Precambrian Bastar Craton (including Proterozoic Chhattisgarh Basin, granitic intrusions etc.) and Eastern Ghat Mobile Belt, Gondwana Godavari and Mahanadi Grabens, Late Cretaceous Deccan Traps etc. The central India is well covered by reconnaissance scale aeromagnetic data. We analyzed this data for mapping the basement by dividing into143 overlapping blocks of 100×100km using least square nonlinear inversion method for fractal distribution of sources. The scaling exponents and depth values are optimized using grid search method. We interpreted estimated depths of anomalous sources as magnetic basement and shallow anomalous magnetic sources. The shallow magnetic anomalies are found to vary from 1 to 3km whereas magnetic basement depths are found to vary from 2km to 7km. The shallowest basement depth of 2km found corresponding to Kanker granites a part of Bastar Craton whereas deepest basement depth of 7km is associated with Godavari Graben and south eastern part of Eastern Ghat Mobile Belts near the Parvatipuram Bobbili fault. The variation of magnetic basement, shallow depths and scaling exponent in the region indicate complex tectonic, heterogeneity and intrusive bodies at different depths which is due to different tectonic processes in the region. The detailed basement depth of central India is presented in this study.

  20. Alternative Fuels Data Center: Fair Oaks Farm Harnesses the Power of

    Science.gov Websites

    Natural Gas from Cow Manure Fair Oaks Farm Harnesses the Power of Natural Gas from Cow Manure Natural Gas from Cow Manure on Facebook Tweet about Alternative Fuels Data Center: Fair Oaks Farm Harnesses the Power of Natural Gas from Cow Manure on Twitter Bookmark Alternative Fuels Data Center: Fair

  1. 14 CFR 27.785 - Seats, berths, litters, safety belts, and harnesses.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... head injury by a safety belt plus a shoulder harness that will prevent the head from contacting any injurious object except as provided for in § 27.562(c)(5). A shoulder harness (upper torso restraint), in... serious injury in an emergency landing as a result of the static inertial load factors specified in § 27...

  2. 14 CFR 27.785 - Seats, berths, litters, safety belts, and harnesses.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... head injury by a safety belt plus a shoulder harness that will prevent the head from contacting any injurious object except as provided for in § 27.562(c)(5). A shoulder harness (upper torso restraint), in... serious injury in an emergency landing as a result of the static inertial load factors specified in § 27...

  3. 14 CFR 27.785 - Seats, berths, litters, safety belts, and harnesses.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... head injury by a safety belt plus a shoulder harness that will prevent the head from contacting any injurious object except as provided for in § 27.562(c)(5). A shoulder harness (upper torso restraint), in... serious injury in an emergency landing as a result of the static inertial load factors specified in § 27...

  4. 14 CFR 27.785 - Seats, berths, litters, safety belts, and harnesses.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... head injury by a safety belt plus a shoulder harness that will prevent the head from contacting any injurious object except as provided for in § 27.562(c)(5). A shoulder harness (upper torso restraint), in... serious injury in an emergency landing as a result of the static inertial load factors specified in § 27...

  5. Subject Load-Harness Interaction During Zero-Gravity Treadmill Exercise

    NASA Technical Reports Server (NTRS)

    McCrory, Jean L.; Baron, Heidi A.; Derr, Janice A.; Davis, Brian L.; Cavanagh, Peter R.

    1996-01-01

    When astronauts exercise on orbit, a subject load device (SLD) must be used to return the subject back to the supporting surface. The load in the SLD needs to be transferred the body by a harness which typically distributes this load between the pelvis and We shoulders. Through the use of a zero-gravity simulator, this research compared subject comfort and ground reaction forces during treadmill running at three levels of subject load (60%,80%, and 100% of body weight) in two harness designs ("shoulder only" and "waist "and shoulder ").

  6. 4. VIEW LOOKING WEST FROM BASEMENT UNDER OPEN CONCOURSE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. VIEW LOOKING WEST FROM BASEMENT UNDER OPEN CONCOURSE - CEILING OF BRICK ARCHES; WOOD PANELS MARK LOCATION OF ORIGINAL GLASS PRISM SKYLIGHTS REPLACED WITH CONCRETE - Pennsylvania Railroad Station, Open Concourse & Concourse Roof Extension, 1101 Liberty Avenue, Pittsburgh, Allegheny County, PA

  7. 58. Corridor, building 500 to building 515, basement level, looking ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    58. Corridor, building 500 to building 515, basement level, looking southeast - Offutt Air Force Base, Strategic Air Command Headquarters & Command Center, Headquarters Building, 901 SAC Boulevard, Bellevue, Sarpy County, NE

  8. Basement, bathroom, looking south U.S. Veterans Hospital, Jefferson Barracks, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Basement, bathroom, looking south - U.S. Veterans Hospital, Jefferson Barracks, Medical Officer in Charge Residence, VA Medical Center, Jefferson Barracks Division 1 Jefferson Barracks Drive, Saint Louis, Independent City, MO

  9. Alport syndrome and Pierson syndrome: Diseases of the glomerular basement membrane.

    PubMed

    Funk, Steven D; Lin, Meei-Hua; Miner, Jeffrey H

    2018-04-16

    The glomerular basement membrane (GBM) is an important component of the kidney's glomerular filtration barrier. Like all basement membranes, the GBM contains type IV collagen, laminin, nidogen, and heparan sulfate proteoglycan. It is flanked by the podocytes and glomerular endothelial cells that both synthesize it and adhere to it. Mutations that affect the GBM's collagen α3α4α5(IV) components cause Alport syndrome (kidney disease with variable ear and eye defects) and its variants, including thin basement membrane nephropathy. Mutations in LAMB2 that impact the synthesis or function of laminin α5β2γ1 (LM-521) cause Pierson syndrome (congenital nephrotic syndrome with eye and neurological defects) and its less severe variants, including isolated congenital nephrotic syndrome. The very different types of kidney diseases that result from mutations in collagen IV vs. laminin are likely due to very different pathogenic mechanisms. A better understanding of these mechanisms should lead to targeted therapeutic approaches that can help people with these rare but important diseases. Copyright © 2017 International Society of Matrix Biology. Published by Elsevier B.V. All rights reserved.

  10. 12. COLD CALIBRATION BLOCKHOUSE BASEMENT VIEW FROM LEFT TO RIGHT, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. COLD CALIBRATION BLOCKHOUSE BASEMENT VIEW FROM LEFT TO RIGHT, CABLE TRAYS, RACKS, CABLE CONNECTION TERMINALS. - Marshall Space Flight Center, East Test Area, Cold Calibration Test Stand, Huntsville, Madison County, AL

  11. STAIRWAY FROM THE PROMENADE TO THE BASEMENT SHOWING SHELTER SIGNAGE. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    STAIRWAY FROM THE PROMENADE TO THE BASEMENT SHOWING SHELTER SIGNAGE. VIEW FACING WEST - U.S. Naval Base, Pearl Harbor, Theater, Hornet Avenue between Enterprise & Pokomoke Streets, Pearl City, Honolulu County, HI

  12. 7. BLOCK HOUSE BASEMENT LOOKING THROUGH DOOR INTO CABLE TUNNEL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. BLOCK HOUSE BASEMENT LOOKING THROUGH DOOR INTO CABLE TUNNEL RUNNING BETWEEN BLOCK HOUSE AND STATIC TEST TOWER. - Marshall Space Flight Center, East Test Area, Block House, Huntsville, Madison County, AL

  13. Paleomagnetism and alteration of lower Paleozoic rocks and Precambrian basement in the SHADS No. 4 drill core, Oklahoma

    NASA Astrophysics Data System (ADS)

    Evans, S. C.; Hamilton, M.; Hardwick, J.; Terrell, C.; Elmore, R. D.

    2017-12-01

    The chacterization of the lower Paleozoic sedimentary rock and the underlying Precambrian basement in northern Oklahoma is currently the subject of research to better understand induced seismicity in Oklahoma. We are investigating approximately 140 meters of igneous basement and over 300 meters of Ordovician Arbuckle Group carbonates and underlying sandstone in the Amoco SHADS No. 4 drill core from Rogers Co., Oklahoma, to better understand the nature, origin, and timing of fluid alteration and the relationship between fluid flow in the Arbuckle Group and the basement. Preliminary attempts to orient the core using the viscous remanent magnetization (VRM) method were unsuccessful, probably due to a steep drilling-induced component. The dolomitized Arbuckle Group contains a characteristic remanent magnetization (ChRM) with shallow inclinations (-5°) and variable declinations that, based on unblocking temperatures, is interpreted to reside in magnetite. This ChRM is interpreted as a chemical remanent magnetization (CRM) acquired in the Permian based on the shallow inclinations. The CRM could be related to hydrothermal fluids which migrated into the rocks in the late Paleozoic, as other studies in northern Oklahoma have reported. The Arbuckle Group dolomites are porous and extensively altered and consist of several generations of dolomite, including baroque dolomite. The basement rock is andesitic to trachytic ignimbrite that exhibits extensive alteration. There are many near-vertical fractures mineralized with epidote that are cross cut by calcite-filled fractures. Anisotropy of magnetic susceptibility (AMS) measurements indicate an oblate fabric in the top of the basement and the overlying sandstones. At greater depths, the AMS is variable and may include both alteration and primary fabrics. Demagnetization of the basement rocks is in the initial stages. We are currently investigating if and how far the alteration in the Arbuckle Group extended into the basement

  14. Estimating the Subsurface Basement Topography of Dodge County, Wisconsin Using Three Dimensional Modeling of Gravity and Aeromagnetic Data

    NASA Astrophysics Data System (ADS)

    MacAlister, E.; Skalbeck, J.; Stewart, E.

    2016-12-01

    Since the late 1800's, geologic studies have been completed in Wisconsin in pursuit of understanding the basement topography and locating economically viable mineral resources. The doubly plunging Baraboo Syncline located in Columbia and Sauk Counties provides a classic record of Precambrian deformation. A similar buried structure is thought to exist in adjacent Dodge County based on a prominent aeromagnetic anomaly. For this study, 3-D modeling of gravity and aeromagnetic survey data was used to approximate the structure of the Precambrian basement topography beneath Dodge County, Wisconsin. The aim of the research was to determine a suitable basement topography grid using potential field data and then use this grid as the base for groundwater flow models. Geosoft Oasis Montaj GM-SYS 3D modeling software was used to build grids of subsurface layers and the model was constrained by well records of basement rock elevations located throughout the county. The study demonstrated that there is a complex network of crystalline basement structures that have been folded through tectonic activity during the Precambrian. A thick layer of iron rich sedimentary material was deposited on top of the basement rocks, causing a distinct magnetic signature that outlined the basement structure in the magnetic survey. Preliminary results reveal an iron layer with a density of 3.7 g/cm3 and magnetic susceptibility of 8000 x 10-6 cgs that is approximately 500 feet thick and ranges between elevations of -300 meters below and 400 meters above sea level. The 3-D model depths are consistent with depths from recent core drilling operations performed by the Wisconsin Geological and Natural History Survey. Knowing the depth to and structure of basement rock throughout Dodge County and Wisconsin plays an important role in understanding the geologic history of the region. Also, better resolution of the basement topography can enhance the accuracy of future groundwater flow models.

  15. Basement diapirism associated with the emplacement of major ophiolite nappes: Some constraints

    NASA Astrophysics Data System (ADS)

    Andrews-Speed, C. P.; Johns, C. C.

    1985-09-01

    The association of basement uplifts with major ophiolite nappes in some Phanerozoic orogenic belts suggests that gravitational instability results in the local diapiric uplift of the basement following ophiolite emplacement. In previous analyses of diapirism in crustal silicate rocks, viscous behaviour of rocks has been assumed. It is argued that this assumption is not valid. An alternative analysis is offered to determine whether or not the stress would be sufficient for diapirism to occur. The negative buoyancy stress resulting from the emplacement of an ophiolite nappe 5-15 km thick onto continental basement may be in the range 10-50 MPa. If the horizontal deviatoric stress is zero, this will be the maximum principal compressive stress. After ophiolite emplacement the thermal profile through the ophiolite and the basement will relax from a saw-tooth form to an equilibrium profile. If the ophiolite is young and thick there will be a zone of ductile strain in the lower part of the ophiolite and in the upper part of the continental basement. Results from steady-state creep experiments suggest that temperatures in this zone may be high enough for a short time after ophiolite emplacement (3 Ma or more) for the rocks in this zone to deform at geologically significant strain rates (10 -14 or greater) in response to the negative buoyancy stress. A thin ophiolite or rapid erosion will result in this ductile zone being absent or too short-lived for significant strain. Aquaeous fluids may reduce the strength of brittle rocks by decreasing the effective normal stress or by encouraging pressure solution creep. Evidence suggests that the deviatoric stress across presently active faults may be as low at 10 MPa. Thus diapirism in response to ophiolite emplacement may occur through brittle strain. Gravity spreading within the ophiolite is an alternative mechanism for accommodating the gravitational instability. The critical evidence lies in the field.

  16. 35. Basement, passage beneath main entrance porch, showing circular skylight ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. Basement, passage beneath main entrance porch, showing circular skylight opening, view to northwest - Portsmouth Naval Hospital, Hospital Building, Rixey Place, bounded by Williamson Drive, Holcomb Road, & The Circle, Portsmouth, Portsmouth, VA

  17. North rear, east part. Ramp leads to basement utility rooms ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    North rear, east part. Ramp leads to basement utility rooms and specimen preparation rooms. - San Bernardino Valley College, Life Science Building, 701 South Mount Vernon Avenue, San Bernardino, San Bernardino County, CA

  18. 21. Generator Room (basement beneath Blacksmith Shop): view looking north ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. Generator Room (basement beneath Blacksmith Shop): view looking north showing remains of 1923 six-cylinder Studebaker engine and a dynamo - Ben Thresher's Mill, State Aid No. 1, Barnet, Caledonia County, VT

  19. The timing of metamorphism in the Odenwald-Spessart basement, Mid-German Crystalline Zone

    NASA Astrophysics Data System (ADS)

    Will, T. M.; Schulz, B.; Schmädicke, E.

    2017-07-01

    New in situ electron microprobe monazite and white mica 40Ar/39Ar step heating ages support the proposition that the Odenwald-Spessart basement, Mid-German Crystalline Zone, consists of at least two distinct crustal terranes that experienced different geological histories prior to their juxtaposition. The monazite ages constrain tectonothermal events at 430 ± 43 Ma, 349 ± 14 Ma, 331 ± 16 Ma and 317 ± 12 Ma/316 ± 4 Ma, and the 40Ar/39Ar analyses provide white mica ages of 322 ± 3 Ma and 324 ± 3 Ma. Granulite-facies metamorphism occurred in the western Odenwald at c. 430 and 349 Ma, and amphibolite-facies metamorphism affected the eastern Odenwald and the central Spessart basements between c. 324 and 316 Ma. We interpret these data to indicate that the Otzberg-Michelbach Fault Zone, which separates the eastern Odenwald-Spessart basement from the Western Odenwald basement, is part of the Rheic Suture, which marks the position of a major Variscan plate boundary separating Gondwana- and Avalonia-derived crustal terranes. The age of the Carboniferous granulite-facies event in the western Odenwald overlaps with the minimum age of eclogite-facies metamorphism in the adjacent eastern Odenwald. The granulite- and eclogite-facies rocks experienced contrasting pressure-temperature paths but occur in close spatial proximity, being separated by the Rheic Suture. As high-pressure and high-temperature metamorphisms are of similar age, we interpret the Odenwald-Spessart basement as a paired metamorphic belt and propose that the adjacent high-pressure and high-temperature rocks were metamorphosed in the same subduction zone system. Juxtaposition of these rocks occurred during the final stages of the Variscan orogeny along the Rheic Suture.

  20. Usability issues concerning child restraint system harness design.

    PubMed

    Rudin-Brown, Christina M; Kumagai, Jason K; Angel, Harry A; Iwasa-Madge, Kim M; Noy, Y Ian

    2003-05-01

    A study was conducted to assess usability issues relating to child restraint system (CRS) harness design. Four convertible child restraint systems representing a wide variety of design features were used. Forty-two participants installed two child test dummies in both forward- and rear-facing configurations either inside or outside a test vehicle. Observer-scored checklists determined the degree to which each harness was installed correctly. Participant-scored questionnaires evaluated the 'ease-of-use' of various design features. While the percentage of correct installations exceeded 83% for all designs when installed in the forward-facing configuration, in the rear-facing position (that intended for children under 9-10 kg), there was a significant (between 65 and 89%) percentage of incorrect installations for all models. This finding is of particular interest and may be indicative of a more generalized problem with 'convertible' CRS designs when they are used in the rear-facing configuration. Furthermore, while certain design features were perceived by users as providing significantly better protection in the event of a collision, these also tended to be the features that were misused most often. The benefits and costs of various design features are discussed, and a method to test harness design usability is presented.

  1. Quick-disconnect harness system for helmet-mounted displays

    NASA Astrophysics Data System (ADS)

    Bapu, P. T.; Aulds, M. J.; Fuchs, Steven P.; McCormick, David M.

    1992-10-01

    We have designed a pilot's harness-mounted, high voltage quick-disconnect connectors with 62 pins, to transmit voltages up to 13.5 kV and video signals with 70 MHz bandwidth, for a binocular helmet-mounted display system. It connects and disconnects with power off, and disconnects 'hot' without pilot intervention and without producing external sparks or exposing hot embers to the explosive cockpit environment. We have implemented a procedure in which the high voltage pins disconnect inside a hermetically-sealed unit before the physical separation of the connector. The 'hot' separation triggers a crowbar circuit in the high voltage power supplies for additional protection. Conductor locations and shields are designed to reduce capacitance in the circuit and avoid crosstalk among adjacent circuits. The quick- disconnect connector and wiring harness are human-engineered to ensure pilot safety and mobility. The connector backshell is equipped with two hybrid video amplifiers to improve the clarity of the video signals. Shielded wires and coaxial cables are molded as a multi-layered ribbon for maximum flexibility between the pilot's harness and helmet. Stiff cabling is provided between the quick-disconnect connector and the aircraft console to control behavior during seat ejection. The components of the system have been successfully tested for safety, performance, ergonomic considerations, and reliability.

  2. Influence of basements, garages, and common hallways on indoor residential volatile organic compound concentrations

    NASA Astrophysics Data System (ADS)

    Dodson, Robin E.; Levy, Jonathan I.; Spengler, John D.; Shine, James P.; Bennett, Deborah H.

    Concentrations of many volatile organic compounds (VOCs) are often higher inside residences than outdoors as a result of sources or activities within the residences. These sources can be located directly in the living space of the home or in areas associated with the home such as an attached garage, basement, or common apartment hallway. To characterize the contributions from these areas to indoor residential concentrations, VOC concentrations were measured inside, outside, and, if present, in the attached garage, basement, or common hallway of an apartment of 55 residences in the Boston area, most over two seasons, as part of the Boston Exposure Assessment in Microenvironments (BEAM) Study. Of the 55 residences in the study, 11 had attached garages and basements, 24 had only basements, 10 other residences had common apartment hallways, and the remaining 10 were treated as single compartment residences. Concentrations in the garage were up to 5-10 times higher at the median than indoor concentrations for mobile source pollutants including benzene, toluene, ethylbenzene, and xylenes. Basement/indoor concentration ratios were significantly >1 for methylene chloride, ethylbenzene, m, p-xylene, and o-xylene, and summer ratios tended to be higher than winter ratios. Approximately, 20-40% of the indoor concentration for compounds associated with gasoline sources, such as methyl t-butyl ether (MTBE), benzene, toluene, ethylbenzene, and xylenes, can be attributed to an attached garage at the residence, with garages laterally attached to the first floor of the home having a larger impact. At the median, basements contributed to approximately 10-20% of the estimated indoor concentrations. For apartments, approximately 5-10% of the estimated indoor concentrations confer with air from the hallway. Contributions of these secondary zones to concentrations in the living area of a home were calculated using concentration and airflow estimates. Our findings illustrate the potential

  3. 17. Woodworking Mill (basement): view looking north showing Ames Iron ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. Woodworking Mill (basement): view looking north showing Ames Iron Works steam boiler; note turbine control handle in middle right of photo - Ben Thresher's Mill, State Aid No. 1, Barnet, Caledonia County, VT

  4. Detail of basement level concrete beams at southwest corner; camera ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of basement level concrete beams at southwest corner; camera facing west. - Mare Island Naval Shipyard, Hospital Ward, Johnson Lane, west side at intersection of Johnson Lane & Cossey Street, Vallejo, Solano County, CA

  5. 17. INTERIOR VIEW OF BASEMENT EXHIBITION OF EVENTS OF CIVIL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. INTERIOR VIEW OF BASEMENT EXHIBITION OF EVENTS OF CIVIL RIGHTS MOVEMENT AND THE 1963 BOMBING OF THE CHURCH, LOOKING SOUTH - Sixteenth Street Baptist Church, 1530 Sixth Avenue North, Birmingham, Jefferson County, AL

  6. Basement membrane of mouse bone marrow sinusoids shows distinctive structure and proteoglycan composition: a high resolution ultrastructural study.

    PubMed

    Inoue, S; Osmond, D G

    2001-11-01

    Venous sinusoids in bone marrow are the site of a large-scale traffic of cells between the extravascular hemopoietic compartment and the blood stream. The wall of the sinusoids consists solely of a basement membrane interposed between a layer of endothelial cells and an incomplete covering of adventitial cells. To examine its possible structural specialization, the basement membrane of bone marrow sinusoids has now been examined by high resolution electron microscopy of perfusion-fixed mouse bone marrow. The basement membrane layer was discontinuous, consisting of irregular masses of amorphous material within a uniform 60-nm-wide space between apposing endothelial cells and adventitial cell processes. At maximal magnifications, the material was resolved as a random arrangement of components lacking the "cord network" formation seen in basement membranes elsewhere. Individual components exhibited distinctive ultrastructural features whose molecular identity has previously been established. By these morphological criteria, the basement membrane contained unusually abundant chondroitin sulfate proteoglycan (CSPG) revealed by 3-nm-wide "double tracks," and moderate amounts of both laminin as dense irregular coils and type IV collagen as 1-1.5-nm-wide filaments, together with less conspicuous amounts of amyloid P forming pentagonal frames. In contrast, 4.5-5-nm-wide "double tracks" characteristic of heparan sulfate proteoglycan (HSPG) were absent. The findings demonstrate that, in comparison with "typical" basement membranes in other tissues, the bone marrow sinusoidal basement membrane is uniquely specialized in several respects. Its discontinuous nature, lack of network organization, and absence of HSPG, a molecule that normally helps to maintain membrane integrity, may facilitate disassembly and reassembly of basement membrane material in concert with movements of adventitial cell processes as maturing hemopoietic cells pass through the sinusoidal wall: the

  7. Harnessing the Power of Information Technology: Open Business Models in Higher Education

    ERIC Educational Resources Information Center

    Sheets, Robert G.; Crawford, Stephen

    2012-01-01

    Higher education is under enormous pressure to improve outcomes and reduce costs. Information technology can help achieve these goals, but only if it is properly harnessed. This article argues that one key to harnessing information technology is business model innovation that results in more "open" and "unbundled" operations in learning and…

  8. 8. SAC command center underground structure, building 501, basement entry, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. SAC command center underground structure, building 501, basement entry, machine room, April 11, 1955 - Offutt Air Force Base, Strategic Air Command Headquarters & Command Center, Command Center, 901 SAC Boulevard, Bellevue, Sarpy County, NE

  9. Dissolution of biogenic ooze over basement edifices in the equatorial Pacific with implications for hydrothermal ventilation of the oceanic crust

    USGS Publications Warehouse

    Bekins, B.A.; Spivack, A.J.; Davis, E.E.; Mayer, L.A.

    2007-01-01

    Recent observations indicate that curious closed depressions in carbonate sediments overlying basement edifices are widespread in the equatorial Pacific. A possible mechanism for their creation is dissolution by fluids exiting basement vents from off-axis hydrothermal flow. Quantitative analysis based on the retrograde solubility of calcium carbonate and cooling of basement fluids during ascent provides an estimate for the dissolution capacity of the venting fluids. Comparison of the dissolution capacity and fluid flux with typical equatorial Pacific carbonate mass accumulation rates shows that this mechanism is feasible. By maintaining sediment-free basement outcrops, the process may promote widespread circulation of relatively unaltered seawater in the basement in an area where average sediment thicknesses are 300-500 m. The enhanced ventilation can explain several previously puzzling observations in this region, including anomalously low heat flux, relatively unaltered seawater in the basement, and aerobic and nitrate-reducing microbial activity at the base of the sediments. ?? 2007 The Geological Society of America.

  10. Harnessing the Power of Light to See and Treat Breast Cancer

    DTIC Science & Technology

    2010-10-01

    Harnessing the power of light to see and treat breast cancer PRINCIPAL INVESTIGATOR: Nirmala Ramanujam, Ph.D...NUMBER Harnessing the power of light to see and treat breast cancer . 5b. GRANT NUMBER W81XWH-09-1-0410 5c. PROGRAM ELEMENT NUMBER 6...optical contrast to develop novel strategies that focus on two breast cancer applications: tumor margin assessment and prediction of response to neo

  11. 32. VIEW OF BASEMENT BELOW BOILER 904 LOOKING SOUTHEAST AT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. VIEW OF BASEMENT BELOW BOILER 904 LOOKING SOUTHEAST AT TURBINE DRIVEN FORCED DRAFT FAN FOR BOILER 904. - New York, New Haven & Hartford Railroad, Cos Cob Power Plant, Sound Shore Drive, Greenwich, Fairfield County, CT

  12. Timing and conditions of regional metamorphism and crustal shearing in the granulite facies basement of south Namibia: Implications for the crustal evolution of the Namaqualand metamorphic basement in the Mesoproterozoic

    NASA Astrophysics Data System (ADS)

    Bial, Julia; Büttner, Steffen; Appel, Peter

    2016-11-01

    Granulite facies basement gneisses from the Grünau area in the Kakamas Domain of the Namaqua-Natal Metamorphic Province in south Namibia show high-grade mineral assemblages, most commonly consisting of garnet, cordierite, sillimanite, alkali feldspar and quartz. Cordierite + hercynitic spinel, and in some places quartz + hercynitic spinel, indicate granulite facies P-T conditions. The peak assemblage equilibrated at 800-850 °C at 4.0-4.5 kbar. Sillimanite pseudomorphs after kyanite1 and late-stage staurolite and kyanite2 indicate that the metamorphic record started and ended within the stability field of kyanite. Monazite in the metamorphic basement gneisses shows a single-phase growth history dated as 1210-1180 Ma, which we interpret as the most likely age of the regional metamorphic peak. This time coincides with the emplacement of granitic plutons in the Grünau region. The ∼10 km wide, NW-SE striking Grünau shear zone crosscuts the metamorphic basement and overprints high-temperature fabrics. In sheared metapelites, the regional metamorphic peak assemblage is largely obliterated, and is replaced by synkinematic biotite2, quartz, alkali feldspar, sillimanite and cordierite or muscovite. In places, gedrite, staurolite, sillimanite and green biotite3 may have formed late- or post-kinematically. The mylonitic mineral assemblage equilibrated at 590-650 °C at 3.5-5.0 kbar, which is similar to a retrograde metamorphic stage in the basement away from the shear zone. Monazite cores in two mylonite samples are similar in texture and age (∼1200 Ma) to monazite in metapelites away from the shear zone. Chemically distinct monazite rims indicate a second growth episode at ∼1130-1120 Ma. This age is interpreted to date the main deformation episode along the Grünau shear zone and the retrograde metamorphic stage seen in the basement. The main episode of ductile shearing along the Grünau shear zone took place 70-80 million years after the thermal peak metamorphism

  13. Basement Membrane Type IV Collagen and Laminin: An Overview of Their Biology and Value as Fibrosis Biomarkers of Liver Disease.

    PubMed

    Mak, Ki M; Mei, Rena

    2017-08-01

    Basement membranes provide structural support to epithelium, endothelium, muscles, fat cells, Schwann cells, and axons. Basement membranes are multifunctional: they modulate cellular behavior, regulate organogenesis, promote tissue repair, form a barrier to filtration and tumor metastasis, bind growth factors, and mediate angiogenesis. All basement membranes contain type IV collagen (Col IV), laminin, nidogen, and perlecan. Col IV and laminin self-assemble into two independent supramolecular networks that are linked to nidogen and perlecan to form a morphological discernable basement membrane/basal lamina. The triple helical region, 7S domain and NCI domain of Col IV, laminin and laminin fragment P1 have been evaluated as noninvasive fibrosis biomarkers of alcoholic liver disease, viral hepatitis, and nonalcoholic fatty liver disease. Elevated serum Col IV and laminin are related to degrees of fibrosis and severity of hepatitis, and may reflect hepatic basement membrane metabolism. But the serum assays have not been linked to disclosing the anatomical sites and lobular distribution of perisinusoidal basement membrane formation in the liver. Hepatic sinusoids normally lack a basement membrane, although Col IV is a normal matrix component of the space of Disse. In liver disease, laminin deposits in the space of Disse and codistributes with Col IV, forming a perisinusoidal basement membrane. Concomitantly, the sinusoidal endothelium loses its fenestrae and is transformed into vascular type endothelium. These changes lead to capillarization of hepatic sinusoids, a significant pathology that impairs hepatic function. Accordingly, codistribution of Col IV and laminin serves as histochemical marker of perisinusoidal basement membrane formation in liver disease. Anat Rec, 300:1371-1390, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  14. Percolation of diagenetic fluids in the Archaean basement of the Franceville basin

    NASA Astrophysics Data System (ADS)

    Mouélé, Idalina Moubiya; Dudoignon, Patrick; Albani, Abderrazak El; Cuney, Michel; Boiron, Marie-Christine; Gauthier-Lafaye, François

    2014-01-01

    The Palaeoproterozoic Franceville basin, Gabon, is mainly known for its high-grade uranium deposits, which are the only ones known to act as natural nuclear fission reactors. Previous work in the Kiéné region investigated the nature of the fluids responsible for these natural nuclear reactors. The present work focuses on the top of the Archaean granitic basement, specifically, to identify and date the successive alteration events that affected this basement just below the unconformity separating it from the Palaeoproterozoic basin. Core from four drill holes crosscutting the basin-basement unconformity have been studied. Dating is based on U-Pb isotopic analyses performed on monazite. The origin of fluids is discussed from the study of fluid inclusion planes (FIP) in quartz from basement granitoids. From the deepest part of the drill holes to the unconformable boundary with the basin, propylitic alteration assemblages are progressively replaced by illite and locally by a phengite + Fe chlorite ± Fe oxide assemblage. Illitic alteration is particularly strong along the sediment-granitoid contact and is associated with quartz dissolution. It was followed by calcite and anhydrite precipitation as fracture fillings. U-Pb isotopic dating outlines three successive events: a 3.0-2.9-Ga primary magmatic event, a 2.6-Ga propylitic alteration and a late 1.9-Ga diagenetic event. Fluid inclusion microthermometry suggests the circulation of three types of fluids: (1) a Na-Ca-rich diagenetic brine, (2) a moderately saline (diagenetic + meteoric) fluid, and (3) a low-salinity fluid of probable meteoric origin. These fluids are similar to those previously identified within the overlying sedimentary rocks of the Franceville basin. Overall, the data collected in this study show that the Proterozoic-Archaean unconformity has operated as a major flow corridor for fluids circulation, around 1.9 Ga. highly saline diagenetic brines; hydrocarbon-rich fluids derived from organic matter

  15. Regulation of the basement membrane by epithelia generated forces

    NASA Astrophysics Data System (ADS)

    Tanner, Kandice

    2012-12-01

    Tumor metastasis involves a progressive loss of tissue architecture and dissolution of structural boundaries between the epithelium and connective tissue. The basement membrane (BM), a specialized network of extracellular matrix proteins forms a barrier that physically restricts pre-invasive lesions such that they remain as local insults. The BM is not a static structure, but one that is constantly regenerated and remodeled in the adult organism. Matrix organization also regulates cell function. Thus alterations in the balance of synthesis, remodeling and proteolytic degradation of the extracellular matrix proteins may contribute to a loss of structural integrity. However, the de novo assembly and maintenance of the complex structural properties of in vivo basement membranes remain elusive. Here, this paper highlights the current understanding on the structural properties and the establishment of the BM, and discusses the potential role of self-generated forces in adult tissue remodeling and the maintenance of the BM as a malignancy suppressor.

  16. 36. Basement, cellar beneath main stairway, with skylight in stair ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    36. Basement, cellar beneath main stairway, with skylight in stair riser, and adjacent storage room, view to east - Portsmouth Naval Hospital, Hospital Building, Rixey Place, bounded by Williamson Drive, Holcomb Road, & The Circle, Portsmouth, Portsmouth, VA

  17. 12. Credit WS. Basement of Mill, showing wooden flywheels to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Credit WS. Basement of Mill, showing wooden flywheels to water wheel and Fairbanks. Morse 20 hp, 350 rpm diesel engine, patented April 20, 1920. - Bunker Hill Mill, County Route 26, Bunker Hill, Berkeley County, WV

  18. 26. OVERALL SHOT OF BASEMENT, MILL NO. 1. ORIGINALLY MACHINE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. OVERALL SHOT OF BASEMENT, MILL NO. 1. ORIGINALLY MACHINE SHOP. PALLETS ON FLOOR ADDED IN LATE 20th C. FOR CLOTH STORAGE. - Prattville Manufacturing Company, Number One, 242 South Court Street, Prattville, Autauga County, AL

  19. Gravitational sliding of the Mt. Etna massif along a sloping basement

    NASA Astrophysics Data System (ADS)

    Murray, John B.; van Wyk de Vries, Benjamin; Pitty, Andy; Sargent, Phil; Wooller, Luke

    2018-04-01

    Geological field evidence and laboratory modelling indicate that volcanoes constructed on slopes slide downhill. If this happens on an active volcano, then the movement will distort deformation data and thus potentially compromise interpretation. Our recent GPS measurements demonstrate that the entire edifice of Mt. Etna is sliding to the ESE, the overall direction of slope of its complex, rough sedimentary basement. We report methods of discriminating the sliding vector from other deformation processes and of measuring its velocity, which averaged 14 mm year-1 during four intervals between 2001 and 2012. Though sliding of one sector of a volcano due to flank instability is widespread and well-known, this is the first time basement sliding of an entire active volcano has been directly observed. This is important because the geological record shows that such sliding volcanoes are prone to devastating sector collapse on the downslope side, and whole volcano migration should be taken into account when assessing future collapse hazard. It is also important in eruption forecasting, as the sliding vector needs to be allowed for when interpreting deformation events that take place above the sliding basement within the superstructure of the active volcano, as might occur with dyke intrusion or inflation/deflation episodes.

  20. 42 CFR 84.201 - Head harnesses; minimum requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... of pressure over the entire area in contact with the face. (2) Facepieces for single-use vinyl... face. (b) Mouthpieces shall be equipped where applicable, with an adjustable and replaceable harness...

  1. 16. June 1974. BASEMENT, VIEW LOOKING SOUTHWEST, SHOWING THE MAIN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. June 1974. BASEMENT, VIEW LOOKING SOUTHWEST, SHOWING THE MAIN LINE SHAFT COMING THROUGH THE WALL FROM THE OTTO ENGINE. - Gruber Wagon Works, Pennsylvania Route 183 & State Hill Road at Red Bridge Park, Bernville, Berks County, PA

  2. MTR BASEMENT. GENERAL ELECTRIC CONTROL CONSOLE FOR AIRCRAFT NUCLEAR PROPULSION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    MTR BASEMENT. GENERAL ELECTRIC CONTROL CONSOLE FOR AIRCRAFT NUCLEAR PROPULSION EXPERIMENT NO. 1. INL NEGATIVE NO. 6510. Unknown Photographer, 9/29/1959 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  3. Basement and cover-rock deformation during Laramide contraction in the northern Madison Range (Montana) and its influence on Cenozoic basin formation

    USGS Publications Warehouse

    Kellogg, K.S.; Schmidt, C.J.; Young, S.W.

    1995-01-01

    Two major Laramide fault systems converge in the northwestern Madison Range: the northwest-striking, southwest-vergent Spanish Peaks reverse fault and the north-striking, east-vergent Hilgard thrust system. Analysis of foliation attitudes in basement gneiss north and south of the Spanish Peaks fault indicates that the basement in thrusted blocks of the Hilgard thrust system have been rotated by an amount similar to that of the basement-cover contact. Steeply dipping, north-striking breccia zones enclosing domains of relatively undeformed basement may have permitted domino-style rotation of basement blocks during simple shear between pairs of thrusts. No hydrocarbon discoveries have been made in this unique structural province. However, petroleum exploration here has focused on basement-cored anticlines, both surface and subthrust, related to the two major Laramide fault systems and on the fault-bounded blocks of Tertiary rocks within the post-Laramide extensional basins. -from Authors

  4. Harnessing Collaborative Annotations on Online Formative Assessments

    ERIC Educational Resources Information Center

    Lin, Jian-Wei; Lai, Yuan-Cheng

    2013-01-01

    This paper harnesses collaborative annotations by students as learning feedback on online formative assessments to improve the learning achievements of students. Through the developed Web platform, students can conduct formative assessments, collaboratively annotate, and review historical records in a convenient way, while teachers can generate…

  5. SRB Altitude Switch Assembly Wire Harness Failure

    NASA Technical Reports Server (NTRS)

    Blanche, Jim

    2002-01-01

    This paper presents an assessment of two wire harness failures that had occurred in Solid Rocket Booster Altitude Switch Assemblies S/N 200001 and S/N 20002. A list of modifications to EDU #4 and modification of qualification units 2000001 and 2000002 are also presented.

  6. 11. INTERIOR DETAIL, BASEMENT, SHOWING CONDUITS LEADING UNDERGROUND TO SWITCHES ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. INTERIOR DETAIL, BASEMENT, SHOWING CONDUITS LEADING UNDERGROUND TO SWITCHES AND SIGNALS - Baltimore & Potomac Interlocking Tower, Adjacent to AMTRAK railroad tracks in block bounded by Howard Street, Jones Falls Expressway, Maryland Avenue & Falls Road, Baltimore, Independent City, MD

  7. Stress rotation along pre-Cenozoic basement structures

    NASA Astrophysics Data System (ADS)

    Reiter, K.; Heidbach, O.; Henk, A.

    2017-12-01

    The in-situ stress state of the Earth's crust is under investigation since decades for both, scientific and economic purposes. Several methods have been established to indicate the contemporary orientation of the maximum compressive horizontal stress (SHmax). It is assumed that the same forces that drive plate motion are the first order stress sources and one could presume that SHmax is always parallel to plate motion, which is the case for some regions. However, deviations from this general trend occur in many regions. Therefore, second and third order sources of stress have been identified that potentially cause regional and local stress rotation with respect to the long wave-length trend imposed by plate tectonic forces. One group of such subordinate stress sources are lateral heterogeneities based on structures, petrothermal or petrophysical properties. The World Stress Map (WSM) project compiles systematically data records of the present day SHmax orientation. The increasing amount of stress orientation data allows to investigate areas with consistent stress rotation, divergent to the regional stress pattern. In our work we analyse the stress pattern variability and its causes beneath Germany. In the Molasse Basin in the Alpine foreland the SHmax orientation is perpendicular to the Alpine front as a consequence of gravitational potential energy of the orogen. SHmax is oriented in N-S direction in the central Alpine foreland and within the North German Basin. Between both, within the Mid-German Crystalline High, SHmax is divergent oriented in SE-NW direction. Neither gravitational potential energy nor petrothermal effects can be indicated as stress source. But when comparing the stress pattern with the Variscan basement structures it is obvious that SHmax is perpendicular oriented to this Palaeozoic basement structures. Therefore, petrophysical heterogeneities can be expected as reason for the observed stress rotation. Two assumptions can be made for the Mid

  8. Modelling the role of basement block rotation and strike-slip faulting on structural pattern in the cover units of fold-and-thrust belts

    NASA Astrophysics Data System (ADS)

    Koyi, Hemin; Nilfouroushan, Faramarz; Hessami, Khaled

    2015-04-01

    A series of scaled analogue models are run to study the degree of coupling between basement block kinematics and cover deformation. In these models, rigid basal blocks were rotated about vertical axis in a "bookshelf" fashion, which caused strike-slip faulting along the blocks and, to some degrees, in the overlying cover units of loose sand. Three different combinations of cover basement deformations are modeled; cover shortening prior to basement fault movement; basement fault movement prior to shortening of cover units; and simultaneous cover shortening with basement fault movement. Model results show that the effect of basement strike-slip faults depends on the timing of their reactivation during the orogenic process. Pre- and syn-orogen basement strike-slip faults have a significant impact on the structural pattern of the cover units, whereas post-orogenic basement strike-slip faults have less influence on the thickened hinterland of the overlying fold-and-thrust belt. The interaction of basement faulting and cover shortening results in formation of rhomb features. In models with pre- and syn-orogen basement strike-slip faults, rhomb-shaped cover blocks develop as a result of shortening of the overlying cover during basement strike-slip faulting. These rhombic blocks, which have resemblance to flower structures, differ in kinematics, genesis and structural extent. They are bounded by strike-slip faults on two opposite sides and thrusts on the other two sides. In the models, rhomb-shaped cover blocks develop as a result of shortening of the overlying cover during basement strke-slip faulting. Such rhomb features are recognized in the Alborz and Zagros fold-and-thrust belts where cover units are shortened simultaneously with strike-slip faulting in the basement. Model results are also compared with geodetic results obtained from combination of all available GPS velocities in the Zagros and Alborz FTBs. Geodetic results indicate domains of clockwise and

  9. Regeneration of the epidermis and basement membrane of the planarian Dugesia japonica after total-body x irradiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hori, I.

    1979-03-01

    Fresh-water planarians were studied to examine effects of x rays on regeneration of the epidermis and basement membrane. During early stages of regeneration, free rhabdite-forming cells were associated with the wound epidermis and recruited it. In later stages, however, a gradual degeneration occurred in the epidermis and cells undergoing epithelization decreased in number. Eventually epidermal cells on the wound surface appeared necrotic as evidenced by pyknotic nuclei and vacuolized dense cytoplasm. The entire basement membrane could not be reconstituted in any stage after wounding though its precursor-like material was secreted in the interspace between epidermis and parenchyma. Morphological changes inmore » extracellular products and in the cells surrounding the products suggest that epidermal cells which have covered the wound surface synthesize precursors of the basement membrane. Possible factors of a characteristic perturbation in epithelization and basement membrane formation after total-body irradiation are discussed.« less

  10. 42 CFR 84.151 - Harness test; minimum requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... concrete floor without disarranging the harness or exerting a pull on the facepiece. (5) The arrangement... manner that prevents a pull equivalent to dragging the maximum length of the hose over a concrete floor...

  11. Asymmetric Effects of Subaerial and Subaqueous Basement Slopes on Self-Similar Morphology of Prograding Deltas

    NASA Astrophysics Data System (ADS)

    Lai, Steven Yueh Jen; Hsiao, Yung-Tai; Wu, Fu-Chun

    2017-12-01

    Deltas form over basements of various slope configurations. While the morphodynamics of prograding deltas over single-slope basements have been studied previously, our understanding of delta progradation over segmented basements is still limited. Here we use experimental and analytical approaches to investigate the deltaic morphologies developing over two-slope basements with unequal subaerial and subaqueous slopes. For each case considered, the scaled profiles of the evolving delta collapse to a single profile for constant water and sediment influxes, allowing us to use the analytical self-similar profiles to investigate the individual effects of subaerial/subaqueous slopes. Individually varying the subaerial/subaqueous slopes exerts asymmetric effects on the morphologies. Increasing the subaerial slope advances the entire delta; increasing the subaqueous slope advances the upstream boundary of the topset yet causes the downstream boundary to retreat. The delta front exhibits a first-retreat-then-advance migrating trend with increasing subaqueous slope. A decrease in subaerial topset length is always accompanied by an increase in subaqueous volume fraction, no matter which segment is steepened. Applications are presented for estimating shoreline retreat caused by steepening of basement slopes, and estimating subaqueous volume and delta front using the observed topset length. The results may have implications for real-world delta systems subjected to upstream tectonic uplift and/or downstream subsidence. Both scenarios would exhibit reduced topset lengths, which are indicative of the accompanied increases in subaqueous volume and signal tectonic uplift and/or subsidence that are at play. We highlight herein the importance of geometric controls on partitioning of sediment between subaerial and subaqueous delta components.

  12. Basement hall under the northeast part of the building. Live ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Basement hall under the northeast part of the building. Live animal cages and dissection rooms are to the right. Note concrete footings. - San Bernardino Valley College, Life Science Building, 701 South Mount Vernon Avenue, San Bernardino, San Bernardino County, CA

  13. An Interactive GIS Procedure for Building and Basement Corrections in Urban Microgravity Surveys

    NASA Astrophysics Data System (ADS)

    Chasseriau, P.; Olivier, R.

    2007-12-01

    Construction of a new underground railway in Lausanne, a highly-urbanized city in Switzerland, was an opportunity to test the feasibility and reliability of microgravity surveys in urban environments. The goal of our microgravity survey was to determine the depth-to-bedrock along the project corridor. Available drilling information allowed us verify the density model obtained. The geophysical results also provided spatially exhaustive subsurface information that could not be obtained with drilling methods alone. Gravimetry is one of the rare geophysical methods that can be used in noisy urban environments. An inevitable constraint of this method is terrain correction. It is not easy to obtain a simple and accurate digital elevation model (DEM) of an urban environment considering that buildings and basements are not included. However, these structures significantly influence gravity measurements. We calculate, with software that we have developed, the influence of buildings and basements in order to correct our gravity data. Our procedure permits the integration of gravity measurements, cadastral information (building typology and geometry) and basement geometry in an Access database that allows interactive determination of the Bouguer anomaly. A geographic information system (GIS) is used to extract building geometries based on cadastral information and to correct the influence of each building using a simplified architectural style. Basement voids are then introduced in the final DEM using building outlines given by cadastral maps. The depths and altitudes of the basements are measured by visiting them, and then linking the results to a regional topographic map. All of these corrections can be calculated before the gravity acquisition has begun in order to optimize the design of the survey. The surveys are executed late at night so as to minimize the effects of traffic noise. 160 gravity measurements were carried out before and after digging of the underground

  14. 57. Entry door (open), BE16, basement level, building 500, looking ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    57. Entry door (open), BE-16, basement level, building 500, looking southeast - Offutt Air Force Base, Strategic Air Command Headquarters & Command Center, Headquarters Building, 901 SAC Boulevard, Bellevue, Sarpy County, NE

  15. 54. Room BF14, IDA room, basement level, building 500, looking ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    54. Room BF-14, IDA room, basement level, building 500, looking west - Offutt Air Force Base, Strategic Air Command Headquarters & Command Center, Headquarters Building, 901 SAC Boulevard, Bellevue, Sarpy County, NE

  16. 56. Entry door (closed), BB16, basement level, building 500, looking ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    56. Entry door (closed), BB-16, basement level, building 500, looking southeast - Offutt Air Force Base, Strategic Air Command Headquarters & Command Center, Headquarters Building, 901 SAC Boulevard, Bellevue, Sarpy County, NE

  17. 55. Room BF9, paper shredding facility, basement level, building 500, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    55. Room BF-9, paper shredding facility, basement level, building 500, looking east - Offutt Air Force Base, Strategic Air Command Headquarters & Command Center, Headquarters Building, 901 SAC Boulevard, Bellevue, Sarpy County, NE

  18. PBF (PER620) interior, basement level. Sampling equipment. Date: May 2004. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PBF (PER-620) interior, basement level. Sampling equipment. Date: May 2004. INEEL negative no. HD-41-5-4 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

  19. Collagen IV Diseases: A Focus on the Glomerular Basement Membrane in Alport Syndrome

    PubMed Central

    Cosgrove, Dominic; Liu, Shiguang

    2016-01-01

    Alport syndrome is the result of mutations in any of three type IV collagen genes, COL4A3, COL4A4, or COL4A5. Because the three collagen chains form heterotrimers, there is an absence of all three proteins in the basement membranes where they are expressed. In the glomerulus, the mature glomerular basement membrane type IV collagen network, normally comprised of two separate networks, α3(IV)/α4(IV)/α5(IV) and α1(IV)/α2(IV), is comprised entirely of collagen α1(IV)/α2. This review addresses the current state of our knowledge regarding the consequence of this change in basement membrane composition, including both the direct, via collagen receptor binding, and indirect, regarding influences on glomerular biomechanics. The state of our current understanding regarding mechanisms of glomerular disease initiation and progression will be examined, as will the current state of the art regarding emergent therapeutic approaches to slow or arrest glomerular disease in Alport patients. PMID:27576055

  20. 7. AGENT STORAGE TANKS LOCATED IN CONCRETE BASEMENT. PHOTOGRAPH IS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. AGENT STORAGE TANKS LOCATED IN CONCRETE BASEMENT. PHOTOGRAPH IS OF THE EASTERN MOST TANK LOOKING SOUTH. - Rocky Mountain Arsenal, Tank House, Quadrant 1, approximately 1000 feet South of December Seventh Avenue; 2200 feet East of D Street, Commerce City, Adams County, CO

  1. 22. INTERIOR VIEW, BASEMENT UNDER NORTH ROOM OF MAIN BLOCK, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. INTERIOR VIEW, BASEMENT UNDER NORTH ROOM OF MAIN BLOCK, VIEW OF NORTHWEST WALL SHOWING CORBELING BASE OF FIRST FLOOR CHIMNEY BLOCK WITH STOVE-PIPE HOLE, AND MORTISE AND TENON FRAMING FOR HEARTH BED - Clifton Farm, Off Baker Road, Frederick, Frederick County, MD

  2. 17. INTERIOR VIEW, BASEMENT, LOOKING SOUTHWEST AT THE GEAR PIT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. INTERIOR VIEW, BASEMENT, LOOKING SOUTHWEST AT THE GEAR PIT BELOW THE GRINDING STONES, SHOWING WOODEN COGS ATTACHED TO UNDERGROUND TURBINES. FRICTION DRIVE VISIBLE BEHIND CONTROL BAR (LEFT) WHICH OPERATES SMUT MILL - Schech's Mill, Beaver Creek State Park, La Crescent, Houston County, MN

  3. 71. (Credit JTL) Pipe gallery looking south in basement underneath ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    71. (Credit JTL) Pipe gallery looking south in basement underneath 1910-11 and 1924 filter wing extensions. Note bottoms of converted New York horizontal pressure filters in right background. - McNeil Street Pumping Station, McNeil Street & Cross Bayou, Shreveport, Caddo Parish, LA

  4. 6. VIEW OF BASEMENT, LOOKING NORTHEAST TOWARD THIRD TURBINE. VISIBLE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. VIEW OF BASEMENT, LOOKING NORTHEAST TOWARD THIRD TURBINE. VISIBLE IS THE LINE SHAFTING THAT DROVE THE MILL'S WATER-POWERED MACHINERY. Photographer: Jet T. Lowe, 1985 - Alexander's Grist Mill, Lock 37 on Ohio & Erie Canal, South of Cleveland, Valley View, Cuyahoga County, OH

  5. Equipment Location Plan, partial basement plan. (Includes identification of each ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Equipment Location Plan, partial basement plan. (Includes identification of each separate CPU, tape drive, hard drive, printer, keyboard, etc., within the data processing center in the southeast part of the basement.) March Air Force Base, Riverside, California, Combat Operations Center, 465-L DPC. By International Electric Corporation, Paramus, New Jersey (3/5/62); for Moffatt and Nichol, Engineers, 122 West Fifth Street, Long Beach, California; for the Corps of Engineers, U.S. Army, Office of the District Engineer, Los Angeles, California. Drawing no. AW-60-02-03, sheet no. 100, approved March, 1962; specifications no. OCI-62-66; D.O. series AW 1596/100, Rev. "A"; file drawer 1290. Last revised 3 October 1966. Scale one-quarter inch to one foot. 28.75x40.5 inches. ink on linen - March Air Force Base, Strategic Air Command, Combat Operations Center, 5220 Riverside Drive, Moreno Valley, Riverside County, CA

  6. PBF (PER620) interior, first basement level. Sampling equipment. Date: March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PBF (PER-620) interior, first basement level. Sampling equipment. Date: March 2004. INEEL negative no. HD-41-4-1 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

  7. Harnessing the Potential of Additive Manufacturing

    DTIC Science & Technology

    2016-12-01

    manufacturing age, which is dominated by standards for materials, processes and process control. Conventional manufacturing is based upon a design that is...documented either in a drawing or a computer-aided design (CAD) file. The manufacturing team then develops a docu- mented public or private process for...31 Defense AT&L: November-December 2016 Harnessing the Potential of Additive Manufacturing Bill Decker Decker is director of Technology

  8. Reliability in fiber optic cable harness manufacturing

    NASA Astrophysics Data System (ADS)

    McCoy, Bruce M.

    Key aspects of manufacturing cable harnesses for aircraft and spacecraft that incorporate optical fiber/cables along with traditional wiring are discussed. Issues regarding feasibility of automation of assembly processes, manual assembly, testing, installation, quality assurance, reliability and maintainability are addressed. Training procedures, formal training programs, and their results are reviewed.

  9. PBF (PER620) interior, basement level. Detail of coolant piping. Date: ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PBF (PER-620) interior, basement level. Detail of coolant piping. Date: May 2004. INEEL negative no. HD-41-5-2 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

  10. Equatorial Pacific gravity lineaments: interpretations with basement topography along seismic reflection lines

    NASA Astrophysics Data System (ADS)

    Mitchell, Neil C.; Davies, Huw

    2018-03-01

    The central equatorial Pacific is interesting for studying clues to upper mantle processes, as the region lacks complicating effects of continental remnants or major volcanic plateaus. In particular, the most recently produced maps of the free-air gravity field from satellite altimetry show in greater detail the previously reported lineaments west of the East Pacific Rise (EPR) that are aligned with plate motion over the mantle and originally suggested to have formed from mantle convection rolls. In contrast, the gravity field 600 km or farther west of the EPR reveals lineaments with varied orientations. Some are also parallel with plate motion over the mantle but others are sub-parallel with fracture zones or have other orientations. This region is covered by pelagic sediments reaching 500-600 m thickness so bathymetry is not so useful for seeking evidence for plate deformation across the lineaments. We instead use depth to basement from three seismic reflection cruises. In some segments of these seismic data crossing the lineaments, we find that the co-variation between gravity and basement depth is roughly compatible with typical densities of basement rocks (basalt, gabbro or mantle), as expected for some explanations for the lineaments (e.g., mantle convection rolls, viscous asthenospheric inter-fingering or extensional deformation). However, some other lineaments are associated with major changes in basement depth with only subtle changes in the gravity field, suggesting topography that is locally supported by varied crustal thickness. Overall, the multiple gravity lineament orientations suggest that they have multiple origins. In particular, we propose that a further asthenospheric inter-fingering instability mechanism could occur from pressure variations in the asthenosphere arising from regional topography and such a mechanism may explain some obliquely oriented gravity lineaments that have no other obvious origin.

  11. 113. ENTRANCE TO GOLD AREA SECURITY ROOM IN BASEMENT, LOCATED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    113. ENTRANCE TO GOLD AREA SECURITY ROOM IN BASEMENT, LOCATED IN BOTTOM OF ORIGINAL WET-BUCKET ELEVATOR SHAFT, ADJACENT TO DIESTER TABLE ROOM. NOTE BOARD WITH INDIVIDUAL TAGS FOR GOLD AREA EMPLOYEES. - Shenandoah-Dives Mill, 135 County Road 2, Silverton, San Juan County, CO

  12. Pneumatic vacuum tube message center, basement room 23, looking southeast ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Pneumatic vacuum tube message center, basement room 23, looking southeast toward doorway and corridor. Note soundproof walls, pedestal flooring, and cable tray suspended from the ceiling - March Air Force Base, Strategic Air Command, Combat Operations Center, 5220 Riverside Drive, Moreno Valley, Riverside County, CA

  13. 10. Historic American Buildings Survey Photocopy BASEMENT PLAN, NORTH ELEVATION, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Historic American Buildings Survey Photocopy BASEMENT PLAN, NORTH ELEVATION, ARCHITECT'S ORIGINAL PLAN Restricted: Not to be reproduced without written permission from Beinecke Rare Books Library, Yale University, New Haven, Conn. - John Pitkin Norton House, 52 Hillhouse Avenue, New Haven, New Haven County, CT

  14. Impact of climate changes during the last 5 million years on groundwater in basement aquifers.

    PubMed

    Aquilina, Luc; Vergnaud-Ayraud, Virginie; Les Landes, Antoine Armandine; Pauwels, Hélène; Davy, Philippe; Pételet-Giraud, Emmanuelle; Labasque, Thierry; Roques, Clément; Chatton, Eliot; Bour, Olivier; Ben Maamar, Sarah; Dufresne, Alexis; Khaska, Mahmoud; Le Gal La Salle, Corinne; Barbecot, Florent

    2015-09-22

    Climate change is thought to have major effects on groundwater resources. There is however a limited knowledge of the impacts of past climate changes such as warm or glacial periods on groundwater although marine or glacial fluids may have circulated in basements during these periods. Geochemical investigations of groundwater at shallow depth (80-400 m) in the Armorican basement (western France) revealed three major phases of evolution: (1) Mio-Pliocene transgressions led to marine water introduction in the whole rock porosity through density and then diffusion processes, (2) intensive and rapid recharge after the glacial maximum down to several hundred meters depths, (3) a present-day regime of groundwater circulation limited to shallow depth. This work identifies important constraints regarding the mechanisms responsible for both marine and glacial fluid migrations and their preservation within a basement. It defines the first clear time scales of these processes and thus provides a unique case for understanding the effects of climate changes on hydrogeology in basements. It reveals that glacial water is supplied in significant amounts to deep aquifers even in permafrosted zones. It also emphasizes the vulnerability of modern groundwater hydrosystems to climate change as groundwater active aquifers is restricted to shallow depths.

  15. Regional trends in radiogenic heat generation in the Precambrian basement of the Western Canadian Basin

    NASA Astrophysics Data System (ADS)

    Jones, F. W.; Majorowicz, J. A.

    Radiogenic heat generation values for 381 basement samples from 229 sites in the western Canadian basin exhibit a lognormal frequency distribution. The mean value = 2.06 (S.D. = 1.22) µWm-3 is larger than the radiogenic heat generation values reported for the shield in the Superior (ca. 1.2 µWm-3, Jessop and Lewis, 1978) and Churchill (ca. 0.7 µWm-3, Drury, 1985) provinces. When equal Log A contour intervals are used to map the basement heat generation, three large zones of relatively high heat generation are found. One coincides with the Peace River Arch basement structure and one with the Athabasca axis (Darnley, 1981). There is no apparent indication of increased heat flow through the Paleozoic formations associated with these two zones. The third zone, in southwestern Saskatchewan, coincides with a high heat flow zone in the Swift Current area. The lack of correlation between heat flow and heat generation in Alberta may be due to the disturbance to the heat flow in the Paleozoic formations by water motion, or may indicate that the heat is from uranium, thorium and potassium isotope enrichment near the basement surface rather than enrichment throughout the entire upper crust.

  16. Harnessing Power from Tides: State of the Art.

    ERIC Educational Resources Information Center

    Ryan, Paul R.

    1979-01-01

    Discussed is the current, world-wide status of tidal energy as a potential power source. Potential sites and global tidal power prospects are identified. New engineering concepts relevant to the harnessing of tidal power are identified and described. (BT)

  17. 30. VIEW WEST IN BASEMENT OF BUILDING 41A; NOTE PLASTIC ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    30. VIEW WEST IN BASEMENT OF BUILDING 41A; NOTE PLASTIC DUCTING WHICH WAS USED TO VENT CORROSIVE FUMES FROM ACID PICKLING AND ELECTROPLATING TANKS - Scovill Brass Works, 59 Mill Street, Waterbury, New Haven County, CT

  18. 29. Basement under central corridor. Shaft on right actuates cross ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    29. Basement under central corridor. Shaft on right actuates cross over valve. Shaft at left operates main flood valve to admit water into the bed. - Lake Whitney Water Filtration Plant, Filtration Plant, South side of Armory Street between Edgehill Road & Whitney Avenue, Hamden, New Haven County, CT

  19. NORTH BASEMENT WALL. IBEAM COLUMNS HAVE BEEN ENCASED IN CONCRETE. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    NORTH BASEMENT WALL. I-BEAM COLUMNS HAVE BEEN ENCASED IN CONCRETE. STEEL BEAMS LAY ACROSS FIRST FLOOR AWAITING CONCRETE POUR. CAMERA LOOKS SOUTHWEST. INL NEGATIVE NO. 735. Unknown Photographer, 10/6/1950 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  20. VIEW OF PROCESS DEVELOPMENT PILE (PDP) TANK, LOOKING WESTSOUTHWEST, BASEMENT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF PROCESS DEVELOPMENT PILE (PDP) TANK, LOOKING WEST-SOUTHWEST, BASEMENT LEVEL -15’. EDGE O FRESONANCE TEST REACTOR (RTR), LATER KNOWN AS LATTICE TEST REACTOR (LTR), VISIBLE TO RIGHT OF PDP TANK - Physics Assembly Laboratory, Area A/M, Savannah River Site, Aiken, Aiken County, SC

  1. An examination of shoulder kinematics and kinetics when using a commercial trunk harness while sheep shearing.

    PubMed

    Gregory, Diane E; Milosavljevic, Stephan; Pal, Poonam; Callaghan, Jack P

    2008-01-01

    Sheep shearing is a very physically demanding occupation, especially on the low back, such that many commercial harnesses have been developed to help reduce the load on the back. Such harnesses have been shown to significantly reduce peak and cumulative low back loads; however, the effect that these harnesses have on the shoulders, which are also highly involved during sheep shearing, has not been previously examined. The purpose of this study was to examine the shoulder postures and cumulative shoulder moments of 12 New Zealand sheep shearers. The use of the trunk harness reduced the percentage of time spent in shoulder flexion greater than 90 degrees and the time spent in shoulder abduction greater than 45 degrees as well as reduced the cumulative net joint flexor, abductor, and adductor shoulder moments by a minimum of 21%, 14%, and 42%, respectively. Therefore, the use of a commercial trunk harness to reduce low back injury may also help to reduce the risk of shoulder injury while sheep shearing.

  2. Projectile Impact Effects on Aircraft Wire Harnesses

    DTIC Science & Technology

    1986-01-08

    circuits Aircraft wire harnesses Modified ETFE Projectile damage and fires 19 ABSTRACT (Continue on reverse if necessary and identit) by block number...Tile Firifinr~ari~ne An overview of tile test fiririý raný,e is shown in Figure b. In tile for-eyrouria is tre rifle, witzh stock removed, utor iuyo e

  3. Heritability and factors associated with number of harness race starts in the Spanish Trotter horse population.

    PubMed

    Solé, M; Valera, M; Gómez, M D; Sölkner, J; Molina, A; Mészáros, G

    2017-05-01

    Longevity/durability is a relevant trait in racehorses. Genetic analysis and knowledge of factors that influence number of harness race starts would be advantageous for both horse welfare and the equine industry. To perform a genetic analysis on harness racing using number of races as a measure of longevity/durability and to identify factors associated with career length in Spanish Trotter Horses (STH). Longitudinal study. Performance data (n = 331,970) on the STH population for harness racing at national level between 1990 and 2014 were used. A grouped data model was fitted to assess factors influencing the risk of ending harness racing career and to estimate the heritability and breeding values for total number of harness races starts as an indicator of horses' longevity and durability. The model included sex, age at first race and first start earnings as time-independent effects, and the calendar year, driver, trainer, racetrack category and season of competition as time-dependent effects. Across the whole dataset, the average number of harness races horses achieved in Spain was 54.7 races, and this was associated with the horses' sex, age at first race and first start earnings, calendar year, driver, racetrack category, and season. The heritability estimated (0.17 ± 0.01) for number of harness race starts indicates that a beneficial response to direct genetic selection can be expected. Data on horses' health status were not available. Horses' total number of harness race starts is a promising tool for genetic analysis and the evaluation of racing longevity and durability. The estimated heritability provides evidence to support the application of genetic selection of total career number of races to improve longevity/durability of STH. © 2016 EVJ Ltd.

  4. Program for improved electrical harness documentation and fabrication

    NASA Technical Reports Server (NTRS)

    1971-01-01

    Computer program provides automated print-out of harness interconnection table and automated cross-check of reciprocal pin/connector assignments, and improves accuracy and reliability of final documented data. Programs and corresponding library tapes are successfully and continuously employed on Nimbus spacecraft programs.

  5. Lithology of the basement underlying the Campi Flegrei caldera: Volcanological and petrological constraints

    NASA Astrophysics Data System (ADS)

    D'Antonio, Massimo

    2011-02-01

    A geologically reasonable working hypothesis is proposed for the lithology of the basement underlying the Campi Flegrei caldera in the ca. 4-8 km depth range. In most current geophysical modeling, this portion of crust is interpreted as composed of Meso-Cenozoic carbonate rocks, underlain by a ca. 1 km thick sill of partially molten rock, thought to be a main magma reservoir. Shallower magma reservoirs likely occur in the 3-4 km depth range. However, the lack of carbonate lithics in any Campi Flegrei caldera volcanic rocks does not support the hypothesis of a limestone basement. Considering the major caldera-forming eruptions, which generated widespread and voluminous ignimbrites during late Quaternary times, including the Campanian Ignimbrite and Neapolitan Yellow Tuff eruptions, the total volume of trachytic to phonolitic ejected magma is conservatively estimated at not less than 350 km 3. Results of least-squared mass-balance calculations suggest that this evolved magma formed through fractional crystallization from at least 2500 km 3 of parent shoshonitic magma, in turn derived from even more voluminous, more mafic, K-basaltic magma. Calculations suggest that shoshonitic magma, likely emplaced at ca. 8 km depth, must have crystallized about 2100 km 3 of solid material, dominated by alkali-feldspar and plagioclase, with a slightly lower amount of mafic minerals, during its route toward shallower magma reservoirs, before feeding the Campi Flegrei large-volume eruptions. The calculated volume of cumulate material, likely syenitic in composition at least in its upper portions, is more than enough to completely fill the basement volume in the 4-8 km depth range beneath the Campi Flegrei caldera, estimated at ca. 1250 km 3. Thus, it is proposed that the basement underlying the Campi Flegrei caldera below 4 km is composed mostly of crystalline igneous rocks, as for many large calderas worldwide. Syenite sensu lato would meet physical properties requirements for

  6. Geochemical variability of the Yucatan basement: Constraints from crystalline clasts in Chicxulub impactites

    NASA Astrophysics Data System (ADS)

    Kettrup, B.; Deutsch, A.

    2003-07-01

    The 65 Ma old Chicxulub impact structure with a diameter of about 180 km is again in the focus of the geosciences because of the recently commenced drilling of the scientific well Yaxcopoil- 1. Chicxulub is buried beneath thick post-impact sediments, yet samples of basement lithologies in the drill cores provide a unique insight into age and composition of the crust beneath Yucatan. This study presents major element, Sr, and Nd isotope data for Chicxulub impact melt lithologies and clasts of basement lithologies in impact breccias from the PEMEX drill cores C-1 and Y-6, as well as data for ejecta material from the K/T boundaries at La Lajilla, Mexico, and Furlo, Italy. The impact melt lithologies have an andesitic composition with significantly varying contents of Al, Ca, and alkali elements. Their present day 87Sr/86Sr ratios cluster at about 0.7085, and 143Nd/144Nd ratios range from 0.5123 to 0.5125. Compared to the melt lithologies that stayed inside the crater, data for ejecta material show larger variations. The 87Sr/86Sr ratios range from 0.7081 for chloritized spherules from La Lajilla to 0.7151 for sanidine spherules from Furlo. The 143Nd/144Nd ratio is 0.5126 for La Lajilla and 0.5120 for the Furlo spherules. In an tCHUR(Nd)-tUR(Sr) diagram, the melt lithologies plot in a field delimited by Cretaceous platform sediments, various felsic lithic clasts and a newly found mafic fragment from a suevite. Granite, gneiss, and amphibolite have been identified among the fragments from crystalline basement gneiss. Their 87Sr/86Sr ratios range from 0.7084 to 0.7141, and their 143Nd/144Nd ratios range from 0.5121 to 0.5126. The TNdDM model ages vary from 0.7 to 1.4 Ga, pointing to different source terranes for these rocks. This leads us to believe that the geological evolution and the lithological composition of the Yucatàn basement is probably more complex than generally assumed, and Gondwanan as well as Laurentian crust may be present in the Yucatàn basement.

  7. Heat flow evidence for hydrothermal circulation in the volcanic basement of subducting plates

    NASA Astrophysics Data System (ADS)

    Harris, R. N.; Spinelli, G. A.; Fisher, A. T.

    2017-12-01

    We summarize and interpret evidence for hydrothermal circulation in subducting oceanic basement from the Nankai, Costa Rica, south central Chile, Haida Gwaii, and Cascadia margins and explore the influence of hydrothermal circulation on plate boundary temperatures in these settings. Heat flow evidence for hydrothermal circulation in the volcanic basement of incoming plates includes: (a) values that are well below conductive (lithospheric) predictions due to advective heat loss, and (b) variability about conductive predictions that cannot be explained by variations in seafloor relief or thermal conductivity. We construct thermal models of these systems that include an aquifer in the upper oceanic crust that enhances heat transport via a high Nusselt number proxy for hydrothermal circulation. At the subduction zones examined, patterns of seafloor heat flow are not well fit by purely conductive simulations, and are better explained by simulations that include the influence of hydrothermal circulation. This result is consistent with the young basement ages (8-35 Ma) of the incoming igneous crust at these sites as well as results from global heat flow analyses showing a significant conductive heat flow deficit for crustal ages less than 65 Ma. Hydrothermal circulation within subducting oceanic basement can have a profound influence on temperatures close to the plate boundary and, in general, leads to plate boundary temperatures that are cooler than those where fluid flow does not occur. The magnitude of cooling depends on the permeability structure of the incoming plate and the evolution of permeability with depth and time. Resolving complex relationships between subduction processes, the permeability structure in the ocean crust, and the dynamics of hydrothermal circulation remains an interdisciplinary frontier.

  8. REACTIVITY MEASUREMENT FACILITY, UNDER CONSTRUCTION OVER MTR CANAL IN BASEMENT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    REACTIVITY MEASUREMENT FACILITY, UNDER CONSTRUCTION OVER MTR CANAL IN BASEMENT OF MTR BUILDING, TRA-603. WOOD PLANKS REST ON CANAL WALL OBSERVABLE IN FOREGROUND. INL NEGATIVE NO. 11745. Unknown Photographer, 8/20/1954 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  9. Harnessing the power of microbial nanowires.

    PubMed

    Reguera, Gemma

    2018-05-27

    The reduction of iron oxide minerals and uranium in model metal reducers in the genus Geobacter is mediated by conductive pili composed primarily of a structurally divergent pilin peptide that is otherwise recognized, processed and assembled in the inner membrane by a conserved Type IVa pilus apparatus. Electronic coupling among the peptides is promoted upon assembly, allowing the discharge of respiratory electrons at rates that greatly exceed the rates of cellular respiration. Harnessing the unique properties of these conductive appendages and their peptide building blocks in metal bioremediation will require understanding of how the pilins assemble to form a protein nanowire with specialized sites for metal immobilization. Also important are insights into how cells assemble the pili to make an electroactive matrix and grow on electrodes as biofilms that harvest electrical currents from the oxidation of waste organic substrates. Genetic engineering shows promise to modulate the properties of the peptide building blocks, protein nanowires and current-harvesting biofilms for various applications. This minireview discusses what is known about the pilus material properties and reactions they catalyse and how this information can be harnessed in nanotechnology, bioremediation and bioenergy applications. © 2018 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology.

  10. Harnessing the Power of Interactivity for Instruction.

    ERIC Educational Resources Information Center

    Borsook, Terry K.

    Arguing that what sets the computer apart from all other teaching devices is its potential for interactivity, this paper examines the concept of interactivity and explores ways in which its power can be harnessed and put to work. A discussion of interactivity in human-to-human communication sets a context within which to view human/computer…

  11. The angle of shoulder slope in normal males as a factor in shoulder-harness design.

    DOT National Transportation Integrated Search

    1965-03-01

    In order to establish criteria for more comfortable shoulder-harness design, this study was conducted to determine the angle of slope of the top of the shoulders where poorly fitting shoulder harness may produce discomfort and, occasionally, function...

  12. 42 CFR 84.78 - Head harnesses; minimum requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Head harnesses; minimum requirements. 84.78 Section 84.78 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self...

  13. 42 CFR 84.78 - Head harnesses; minimum requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Head harnesses; minimum requirements. 84.78 Section 84.78 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self...

  14. 42 CFR 84.78 - Head harnesses; minimum requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Head harnesses; minimum requirements. 84.78 Section 84.78 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self...

  15. 42 CFR 84.78 - Head harnesses; minimum requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Head harnesses; minimum requirements. 84.78 Section 84.78 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self...

  16. 42 CFR 84.78 - Head harnesses; minimum requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Head harnesses; minimum requirements. 84.78 Section 84.78 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self...

  17. Manufacture and quality control of interconnecting wire harnesses

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Four-volume series of documents has been prepared as standard reference. Each volume may be used separately and covers wire and cable preparation as well as harness fabrication and installation. Series should be useful addition to libraries of manufactures of electrical and electronic equipment.

  18. 15. ELECTRICAL REACTOR SHELVES, CONSTRUCTED OF CONCRETE IN THE BASEMENT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. ELECTRICAL REACTOR SHELVES, CONSTRUCTED OF CONCRETE IN THE BASEMENT ALONG EAST WALL, WITH REACTOR PADS BEHIND FRAMED AND SCREENED CAGE, AND PORCELAIN-LINED CABLE DUCTS VISIBLE IN WALL NEAR FLOOR AT REAR - Bonneville Power Administration South Bank Substation, I-84, South of Bonneville Dam Powerhouse, Bonneville, Multnomah County, OR

  19. [Relationship between the changes in ischemia/reperfusion cerebro-microvessel basement membrane injury and gelatinase system in senile rat].

    PubMed

    Li, Jian-sheng; Liu, Ke; Liu, Jing-xia; Wang, Ming-hang; Zhao, Yue-wu; Liu, Zheng-guo

    2008-11-01

    To study the relationship of cerebro-microvessel basement membrane injury and gelatinase system after cerebral ischemia/reperfusion (I/R) in aged rats. Cerebral I/R injury model was reproduced by intraluminal silk ligature thrombosis of the middle cerebral artery occlusion (MCAO). Rats were divided randomly into sham control and I/R groups in young rats [ischemia 3 hours (I 3 h) and reperfusion 6 hours (I/R 6 h), 12 hours (I/R 12 h), 24 hours (I/R 24 h), 3 days (I/R 3 d), 6 days (I/R 6 d)], and sham control group and I/R group in aged rats (I 3 h and I/R 6 h, I/R 12 h, I/R 24 h , I/R 3 d, I/R 6 d). The change in cerebro-cortex microvessel basement membrane structure, basement membrane type IV collagen (Col IV) and laminin (LN) contents, matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) expression in every group were determined with immunohistochemical method and zymogram analysis. With the increase in age, Col IV and LN contents of the microvessel basement membrane were increased, and MMP-2 and MMP-9 expressions were stronger. With prolongation of I/R, the degradation of microvessel basement membrane components (Col IV and LN) was positively correlated with the duration of cerebral I/R. MMP-2 expression was increased gradually, and MMP-9 and TIMP-1 expression increased at the beginning and decreased subsequently. Col IV(I 3 h, I/R 6 h , I/R 12 h), LN (I 3 h, I/R 6-24 h), MMP-2 (I 3 h, I/R 6 h-6 d) and MMP-9 (I 3 h, I/R 6-24 h) expression level in aged rats with I/R injury were higher, and TIMP-1 (I/R 24 h) expression was lower than those in young rats (P<0.05 or P<0.01). In addition, changes in MMP-2 and MMP-9 contents as determined by zymogram analysis method coincided with their immunoexpression. With the increase of age, alteration in membrane components of cerebro-microvessel basement membrane in rats is related with MMPs and TIMP. Cerebro-microvessel basement membrane injury is more serious in aged rats than that of young rats

  20. 14 CFR 91.107 - Use of safety belts, shoulder harnesses, and child restraint systems.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Use of safety belts, shoulder harnesses... OPERATING AND FLIGHT RULES Flight Rules General § 91.107 Use of safety belts, shoulder harnesses, and child... board is briefed on how to fasten and unfasten that person's safety belt and, if installed, shoulder...

  1. 14 CFR 91.107 - Use of safety belts, shoulder harnesses, and child restraint systems.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Use of safety belts, shoulder harnesses... OPERATING AND FLIGHT RULES Flight Rules General § 91.107 Use of safety belts, shoulder harnesses, and child... board is briefed on how to fasten and unfasten that person's safety belt and, if installed, shoulder...

  2. 14 CFR 91.107 - Use of safety belts, shoulder harnesses, and child restraint systems.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Use of safety belts, shoulder harnesses... OPERATING AND FLIGHT RULES Flight Rules General § 91.107 Use of safety belts, shoulder harnesses, and child... board is briefed on how to fasten and unfasten that person's safety belt and, if installed, shoulder...

  3. 14 CFR 91.107 - Use of safety belts, shoulder harnesses, and child restraint systems.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Use of safety belts, shoulder harnesses... OPERATING AND FLIGHT RULES Flight Rules General § 91.107 Use of safety belts, shoulder harnesses, and child... board is briefed on how to fasten and unfasten that person's safety belt and, if installed, shoulder...

  4. 42 CFR 84.1138 - Head harnesses; minimum requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Head harnesses; minimum requirements. 84.1138 Section 84.1138 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Dust, Fume...

  5. 42 CFR 84.1138 - Head harnesses; minimum requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Head harnesses; minimum requirements. 84.1138 Section 84.1138 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Dust, Fume...

  6. 42 CFR 84.1138 - Head harnesses; minimum requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Head harnesses; minimum requirements. 84.1138 Section 84.1138 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Dust, Fume...

  7. 42 CFR 84.1138 - Head harnesses; minimum requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Head harnesses; minimum requirements. 84.1138 Section 84.1138 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Dust, Fume...

  8. 42 CFR 84.1138 - Head harnesses; minimum requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Head harnesses; minimum requirements. 84.1138 Section 84.1138 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Dust, Fume...

  9. 42 CFR 84.121 - Head harnesses; minimum requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Head harnesses; minimum requirements. 84.121 Section 84.121 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Gas Masks...

  10. 42 CFR 84.121 - Head harnesses; minimum requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Head harnesses; minimum requirements. 84.121 Section 84.121 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Gas Masks...

  11. 42 CFR 84.121 - Head harnesses; minimum requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Head harnesses; minimum requirements. 84.121 Section 84.121 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Gas Masks...

  12. 42 CFR 84.121 - Head harnesses; minimum requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Head harnesses; minimum requirements. 84.121 Section 84.121 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Gas Masks...

  13. 42 CFR 84.121 - Head harnesses; minimum requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Head harnesses; minimum requirements. 84.121 Section 84.121 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Gas Masks...

  14. Identification of the cutaneous basement membrane zone antigen and isolation of antibody in linear immunoglobulin A bullous dermatosis.

    PubMed Central

    Zone, J J; Taylor, T B; Kadunce, D P; Meyer, L J

    1990-01-01

    Linear IgA bullous dermatosis (LABD) is a rare blistering skin disease characterized by basement membrane zone deposition of IgA. This study identifies a tissue antigen detected by patient serum and then isolates the autoantibody using epidermis and protein bands blotted on nitrocellulose as immunoabsorbents. Sera from 10 patients (9 with cutaneous disease and 1 with cicatrizing conjunctivitis) were evaluated. Indirect immunofluorescence revealed an IgA anti-basement membrane antibody in 6 of 10 sera with monkey esophagus substrate and 9 of 10 sera with human epidermal substrate. Immunoblotting was performed on epidermal and dermal extracts prepared from skin separated at the basement membrane zone with either sodium chloride or EDTA. Saline-separated skin expressed a 97-kD band in dermal extract alone that was recognized by 4 of 10 sera. EDTA-separated skin expressed the 97-kD band in both epidermal (4 of 10 sera) and dermal (6 of 10 sera) extract. Immunoabsorption of positive sera with epidermis purified an IgA antibody that reacted uniquely with the 97-kD band. In addition, IgA antibody bound to nitrocellulose was eluted from the 97-kD band and found to uniquely bind basement membrane zone. It is likely that the 97-kD protein identified by these techniques is responsible for basement membrane binding of IgA in LABD. Images PMID:2107211

  15. Basement Membrane Defects in Genetic Kidney Diseases

    PubMed Central

    Chew, Christine; Lennon, Rachel

    2018-01-01

    The glomerular basement membrane (GBM) is a specialized structure with a significant role in maintaining the glomerular filtration barrier. This GBM is formed from the fusion of two basement membranes during development and its function in the filtration barrier is achieved by key extracellular matrix components including type IV collagen, laminins, nidogens, and heparan sulfate proteoglycans. The characteristics of specific matrix isoforms such as laminin-521 (α5β2γ1) and the α3α4α5 chain of type IV collagen are essential for the formation of a mature GBM and the restricted tissue distribution of these isoforms makes the GBM a unique structure. Detailed investigation of the GBM has been driven by the identification of inherited abnormalities in matrix proteins and the need to understand pathogenic mechanisms causing severe glomerular disease. A well-described hereditary GBM disease is Alport syndrome, associated with a progressive glomerular disease, hearing loss, and lens defects due to mutations in the genes COL4A3, COL4A4, or COL4A5. Other proteins associated with inherited diseases of the GBM include laminin β2 in Pierson syndrome and LMX1B in nail patella syndrome. The knowledge of these genetic mutations associated with GBM defects has enhanced our understanding of cell–matrix signaling pathways affected in glomerular disease. This review will address current knowledge of GBM-associated abnormalities and related signaling pathways, as well as discussing the advances toward disease-targeted therapies for patients with glomerular disease. PMID:29435440

  16. Harnessing Energy from the Sun for Six Billion People

    ScienceCinema

    Nocera, Daniel

    2018-05-24

    Daniel Nocera, a Massachusetts Institute of Technology professor whose recent research focuses on solar-powered fuels, presents a Brookhaven Science Associates Distinguished Lecture, titled "Harnessing Energy from the Sun for Six Billion People -- One at a Time."

  17. 5. INTERIOR VIEW OF BASEMENT, LOOKING WEST. DEEP DRAW, HEAVY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. INTERIOR VIEW OF BASEMENT, LOOKING WEST. DEEP DRAW, HEAVY PRESS MANUFACTURED BY E. W. BLISS CO., BROOKLYN, NEW YORK. PRESS #3-3/4 S, PATENTED BY E. W. BLISS CO., AUGUST 16, 1892, AND JANUARY 31, 1893. THIS PRESS DATES FROM CA. 1920. - Illinois Pure Aluminum Company, 109 Holmes Street, Lemont, Cook County, IL

  18. ETR BUILDING, TRA642, INTERIOR. BASEMENT. ROLLUP DOOR TO CUBICLE POSTS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ETR BUILDING, TRA-642, INTERIOR. BASEMENT. ROLLUP DOOR TO CUBICLE POSTS CAUTION SIGNS BECAUSE OF SODIUM HAZARD WITHIN. INL NEGATIVE NO. HD24-3-1. Mike Crane, Photographer, 11/2000 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  19. MTR WING, TRA604, INTERIOR. BASEMENT. WEST CORRIDOR. CAMERA FACES NORTH. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    MTR WING, TRA-604, INTERIOR. BASEMENT. WEST CORRIDOR. CAMERA FACES NORTH. HVAC AREA IS AT RIGHT OF CORRIDOR. INL NEGATIVE NO. HD46-13-3. Mike Crane, Photographer, 2/2005 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  20. PBF Reactor Building (PER620). Camera in first basement, facing south ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PBF Reactor Building (PER-620). Camera in first basement, facing south and upward toward main floor. Cable trays being erected. Photographer: Kirsh. Date: May 20, 1969. INEEL negative no. 69-3110 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

  1. PBF (PER620) interior, basement level. Concrete wall shows outline of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PBF (PER-620) interior, basement level. Concrete wall shows outline of reactor basin. Sign says, "Flashing Light - Reactor On - Evacuate Area." Date: May 2004. INEEL negative no. HD-41-5-3 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

  2. ETR BUILDING, TRA642, INTERIOR. BASEMENT. LIQUID SODIUM PIPING INSIDE CUBICLE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ETR BUILDING, TRA-642, INTERIOR. BASEMENT. LIQUID SODIUM PIPING INSIDE CUBICLE SHOWN IN ID-33-G-101. INL NEGATIVE NO. HD24-3-4. Mike Crane, Photographer, 11/2000 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  3. Numerical analysis of temperature distribution due to basement radiogenic heat production, St. Lawrence Lowlands, eastern Canada

    NASA Astrophysics Data System (ADS)

    Liu, Hejuan; Giroux, Bernard; Harris, Lyal B.; Mansour, John

    2017-04-01

    Although eastern Canada is considered as having a low potential for high-temperature geothermal resources, the possibility for additional localized radioactive heat sources in Mesoproterozoic Grenvillian basement to parts of the Palaeozoic St. Lawrence Lowlands in Quebec, Canada, suggests that this potential should be reassessed. However, such a task remains hard to achieve due to scarcity of heat flow data and ambiguity about the nature of the basement. To get an appraisal, the impact of radiogenic heat production for different Grenville Province crystalline basement units on temperature distribution at depth was simulated using the Underworld Geothermal numerical modelling code. The region south of Trois-Rivières was selected as representative for the St. Lawrence Lowlands. An existing 3D geological model based on well log data, seismic profiles and surface geology was used to build a catalogue of plausible thermal models. Statistical analyses of radiogenic element (U, Th, K) concentrations from neighbouring outcropping Grenville domains indicate that the radiogenic heat production of rocks in the modelled region is in the range of 0.34-3.24 μW/m3, with variations in the range of 0.94-5.83 μW/m3 for the Portneuf-Mauricie (PM) Domain, 0.02-4.13 μW/m3 for the Shawinigan Domain (Morin Terrane), and 0.34-1.96 μW/m3 for the Parc des Laurentides (PDL) Domain. Various scenarios considering basement characteristics similar to the PM domain, Morin Terrane and PDL Domain were modelled. The results show that the temperature difference between the scenarios can be as much as 12 °C at a depth of 5 km. The results also show that the temperature distribution is strongly affected by both the concentration of radiogenic elements and the thermal conductivity of the basement rocks. The thermal conductivity in the basement affects the trend of temperature change between two different geological units, and the spatial extent of thermal anomalies. The validity of the results was

  4. 11. VIEW NORTH OF MACHINE SHOP IN BASEMENT OF OLD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. VIEW NORTH OF MACHINE SHOP IN BASEMENT OF OLD POWERHOUSE, WITH PIPECUTTER (LEFT), DRILL PRESS LEFT (CENTER), AND GRINDER (RIGHT CENTER) BENEATH LINE SHAFTING) - Trenton Falls Hydroelectric Station, Powerhouse & Substation, On west bank of West Canada Creek, along Trenton Falls Road, 1.25 miles north of New York Route 28, Trenton Falls, Oneida County, NY

  5. 7. INTERIOR VIEW OF BASEMENT OF CA. 1948 FACTORY ADDITION, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. INTERIOR VIEW OF BASEMENT OF CA. 1948 FACTORY ADDITION, LOOKING SOUTHEAST. AT CENTER IS A DEEP-BRAWN, HEAVY PRESS MANUFACTURED BY E. W. BLISS CO., BROOKLYN, NEW YORK. PRESS #3-1/2-C PATENTED BY E. W. BLISS CO., 1893. MANUFACTURER'S PLATE INDICATES PRESS DATES FROM 1922. - Illinois Pure Aluminum Company, 109 Holmes Street, Lemont, Cook County, IL

  6. Detecting Contaminated Drinking Water: Harnessing Consumer Complaints

    DTIC Science & Technology

    2004-11-10

    indicators of contaminated water, before effected people seek medical assistance. One of the most important qualities of drinking water consumers is...of people exposed to the contaminated water. 9. Consumer complaints can be helpful in determining the location of and isolating contaminated...Water: Harnessing Consumer Complaints Andrew J. Whelton 1 , Andrea M. Dietrich 2 , Gary A. Burlingame 3 , Margaret F. Cooney 1 1 U.S. Army

  7. 31. VIEW EAST IN BASEMENT OF BUILDING 41A; NOTE REMAINS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    31. VIEW EAST IN BASEMENT OF BUILDING 41A; NOTE REMAINS OF SUPPORTS FOR OVERHEAD TROLLEY SYSTEM AT LEFT CENTER OF PHOTOGRAPH; TROLLEY SYSTEM WAS USED TO CARRY BASKETS OF SMALL PARTS ALONG THE ELECTROPLATING LINE - Scovill Brass Works, 59 Mill Street, Waterbury, New Haven County, CT

  8. PBF (PER620) interior, first basement. Detail of valves and other ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PBF (PER-620) interior, first basement. Detail of valves and other penetrations along wall. Bricks are made of high density shielding materials. Date: March 2004. INEEL negative no. HD-41-4-2 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

  9. Lithologies of the basement complex (Devonian and older) in the National Petroleum Reserve - Alaska

    USGS Publications Warehouse

    Dumoulin, Julie A.; Houseknecht, David W.

    2001-01-01

    Rocks of the basement complex (Devonian and older) were encountered in at least 30 exploratory wells in the northern part of the NPRA. Fine-grained, variably deformed sedimentary rocks deposited in a slope or basinal setting predominate and include varicolored (mainly red and green) argillite in the Simpson area, dark argillite and chert near Barrow, and widespread gray argillite. Chitinozoans of Middle-Late Ordovician and Silurian age occur in the dark argillite and chert unit. Sponge spicules and radiolarians establish a Phanerozoic age for the varicolored and gray argillite units, both of which contain local interbeds of chert-rich sandstone and silt-stone. Conglomerate and sandstone, also chert-rich but interbedded with mudstone and coal and of Early-Middle Devonian age, occur in the Topagoruk area; these strata formed in a fluvial environment. At East Teshekpuk, granite of probable Devonian age was penetrated. Brecciated, quartz-veined rock of uncertain protolith that may be part of the basement complex was encountered in the Ikpikpuk well. Seismic data indicate that angular unconformities truncate all sedimentary units of the basement complex in NPRA. Rocks correlative in age and lithofacies with the dark argillite and chert unit occur in the subsurface near Prudhoe Bay. Other argillite units in NPRA have similarities to basement rocks in the subsurface adjacent to ANWR and the Ordovician-Silurian Iviagik Group at Cape Lisburne, but lack the interbedded limestones found in the ANWR strata, and are less metamorphosed than, and compositionally distinct from, the Iviagik. The Topagoruk conglomerate and the East Teshekpuk granite resemble the Ulungarat formation and the Okpilak batholith, respectively, in the northeastern Brooks Range.

  10. Magnetic basement and crustal structure in the Arabia-Eurasia collision zone from a combined gravity and magnetic model

    NASA Astrophysics Data System (ADS)

    Mousavi, Naeim; Ebbing, Jörg

    2017-04-01

    In this study, we investigate the magnetic basement and crustal structure in the region of Iran by inverse and forward modeling of aeromagnetic data and gravity data. The main focus is on the definition of the magnetic top basement. The combination of multiple shallow magnetic sources and an assumed shallow Curie isotherm depth beneath the Iranian Plateau creates a complex magnetic architecture over the area. Qualitative analysis, including pseudo gravity, wavelength filtering and upward continuation allowed a first separation of probable deep and shallow features, like the Sanandaj Sirjan zone, Urumieh Dokhtar Magmatic Assemblage, Kopet Dagh structural unit and Central Iran domain. In the second step, we apply inverse modeling to generate an estimate of the top basement geometry. The initial model was established from top basement to (a) constant depth of 25 km and (b) Moho depth. The inversion result was used as starting model for more detailed modelling in 3D to evaluate the effect of susceptibility heterogeneities in the crust. Subsequently, the model was modified with respect to tectonic and geological characterization of the region. Further modification of model in regards more details of susceptibility distribution was led to separating upper crust to different magnetic domains. In addition, we refined the top basement geometry by using terrestrial gravity observation as well. The best fitting model is consistent with the Curie isotherm depth as the base of magnetization. The Curie isotherm was derived from independent geophysical-petrological model.

  11. Effect of basement structure and salt tectonics on deformation styles along strike: An example from the Kuqa fold-thrust belt, West China

    NASA Astrophysics Data System (ADS)

    Neng, Yuan; Xie, Huiwen; Yin, Hongwei; Li, Yong; Wang, Wei

    2018-04-01

    The Kuqa fold-thrust belt (KFTB) has a complex thrust-system geometry and comprises basement-involved thrusts, décollement thrusts, triangle zones, strike-slip faults, transpressional faults, and pop-up structures. These structures, combined with the effects of Paleogene salt tectonics and Paleozoic basement uplift form a complex structural zone trending E-W. Interpretation and comprehensive analysis of recent high-quality seismic data, field observations, boreholes, and gravity data covering the KFTB has been performed to understand the characteristics and mechanisms of the deformation styles along strike. Regional sections, fold-thrust system maps of the surface and the sub-salt layer, salt and basement structure distribution maps have been created, and a comprehensive analysis of thrust systems performed. The results indicate that the thrust-fold system in Paleogene salt range can be divided into five segments from east to west: the Kela-3, Keshen, Dabei, Bozi, and Awate segments. In the easternmost and westernmost parts of the Paleogene salt range, strike-slip faulting and basement-involved thrusting are the dominant deformation styles, as basement uplift and the limits of the Cenozoic evaporite deposit are the main controls on deformation. Salt-core detachment fold-thrust systems coincide with areas of salt tectonics, and pop-up, imbricate, and duplex structures are associated with the main thrust faults in the sub-salt layer. Distribution maps of thrust systems, basement structures, and salt tectonics show that Paleozoic basement uplift controlled the Paleozoic foreland basin morphology and the distribution of Cenozoic salt in the KFTB, and thus had a strong influence on the segmented structural deformation and evolution of the fold-thrust belt. Three types of transfer zone are identified, based on the characteristics of the salt layer and basement uplift, and the effects of these zones on the fault systems are evaluated. Basement uplift and the boundary of

  12. Effects of harness-attached transmitters on premigration and reproduction of Brant

    USGS Publications Warehouse

    Ward, David H.; Flint, Paul L.

    1995-01-01

    Radio transmitters are an important tool in waterfowl ecology studies, but little is known about their effects on free-ranging geese. We attached transmitters to female brant (Branta bernicla nigricans) to investigate migration schedules at a fall staging area, return rates to nesting grounds, and nesting rates of returning females in subsequent breeding seasons. Radio-tagged females (n = 62) carried either 35-g back-mounted transmitters attached with ribbon harnesses, or 26- or 32-g back-mounted transmitters affixed with plastic-coated wire harnesses (Dwyer 1972). Arrival and departure schedules at Izembek Lagoon, Alaska, did not differ (P > 0.05) between radio-tagged females and the entire population in 1987-89. Color-banded females with transmitters returned to the breeding colony in subsequent nesting seasons (1988-92) at a lower (P ≤ 0.003) rate (≤4%) than color-banded females without transmitters (57-83%). The 1 returning color-banded female with a transmitter did not breed, while an average 90% of the returning color-banded females without transmitters nested in subsequent breeding seasons (P = 0.005). Back-mounted, harness-attached transmitters may bias data in studies of waterfowl behavior, productivity, and survival.

  13. Effects of firefighters' self-contained breathing apparatus' weight and its harness design on the physiological and subjective responses.

    PubMed

    Bakri, Ilham; Lee, Joo-Young; Nakao, Kouhei; Wakabayashi, Hitoshi; Tochihara, Yutaka

    2012-01-01

    To examine the effects of firefighters' self-contained breathing apparatus' (SCBA) weight and its harness design on the physiological and subjective responses, eight male students performed treadmill exercise under four conditions: the 8 kg firefighter protective clothing (PC) (Control), the PC + an 11 kg SCBA with an old harness (Test A), the PC + a 6.4 kg SCBA with an old harness (Test B) and the PC + a 6.4 kg SCBA with a new harness (Test C), at ambient temperatures (T(a)) of 22°C and 32°C. Besides highlighting the fact that a heavy SCBA had a significant effect on the oxygen consumption and metabolic rate, this experiment also found that in a T(a) of 32°C, in particular, the combined effect of 4.7 kg lighter SCBA and new harness design could reduce metabolic rate and improved subjective muscle fatigue and thermal discomfort. An effort to alleviate the physiological and subjective burden of firefighters by reducing the weight of SCBA and by using the new harness design has provided satisfactory results in reduced oxygen consumption and in improved subjective responses in a hot air environment.

  14. PBF (PER620) interior, second basement level. Coolant and tank piping. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PBF (PER-620) interior, second basement level. Coolant and tank piping. Mark on vertical pipe says, "H.P. Demin. Water." (High pressure demineralized water.) Date: March 2004. INEEL negative no. HD-41-4-3 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

  15. Age of Izu-Bonin-Mariana arc basement

    NASA Astrophysics Data System (ADS)

    Ishizuka, Osamu; Hickey-Vargas, Rosemary; Arculus, Richard J.; Yogodzinski, Gene M.; Savov, Ivan P.; Kusano, Yuki; McCarthy, Anders; Brandl, Philipp A.; Sudo, Masafumi

    2018-01-01

    Documenting the early tectonic and magmatic evolution of the Izu-Bonin-Mariana (IBM) arc system in the Western Pacific is critical for understanding the process and cause of subduction initiation along the current convergent margin between the Pacific and Philippine Sea plates. Forearc igneous sections provide firm evidence for seafloor spreading at the time of subduction initiation (52 Ma) and production of "forearc basalt". Ocean floor drilling (International Ocean Discovery Program Expedition 351) recovered basement-forming, low-Ti tholeiitic basalt crust formed shortly after subduction initiation but distal from the convergent margin (nominally reararc) of the future IBM arc (Amami Sankaku Basin: ASB). Radiometric dating of this basement gives an age range (49.3-46.8 Ma with a weighted average of 48.7 Ma) that overlaps that of basalt in the present-day IBM forearc, but up to 3.3 m.y. younger than the onset of forearc basalt activity. Similarity in age range and geochemical character between the reararc and forearc basalts implies that the ocean crust newly formed by seafloor spreading during subduction initiation extends from fore- to reararc of the present-day IBM arc. Given the age difference between the oldest forearc basalt and the ASB crust, asymmetric spreading caused by ridge migration might have taken place. This scenario for the formation of the ASB implies that the Mesozoic remnant arc terrane of the Daito Ridges comprised the overriding plate at subduction initiation. The juxtaposition of a relatively buoyant remnant arc terrane adjacent to an oceanic plate was more favourable for subduction initiation than would have been the case if both downgoing and overriding plates had been oceanic.

  16. Inhibition of laminin alpha 1-chain expression leads to alteration of basement membrane assembly and cell differentiation

    PubMed Central

    1996-01-01

    The expression of the constituent alpha 1 chain of laminin-1, a major component of basement membranes, is markedly regulated during development and differentiation. We have designed an antisense RNA strategy to analyze the direct involvement of the alpha 1 chain in laminin assembly, basement membrane formation, and cell differentiation. We report that the absence of alpha 1-chain expression, resulting from the stable transfection of the human colonic cancer Caco2 cells with an eukaryotic expression vector comprising a cDNA fragment of the alpha 1 chain inserted in an antisense orientation, led to (a) an incorrect secretion of the two other constituent chains of laminin-1, the beta 1/gamma 1 chains, (b) the lack of basement membrane assembly when Caco2-deficient cells were cultured on top of fibroblasts, assessed by the absence of collagen IV and nidogen deposition, and (c) changes in the structural polarity of cells accompanied by the inhibition of an apical digestive enzyme, sucrase-isomaltase. The results demonstrate that the alpha 1 chain is required for secretion of laminin-1 and for the assembly of basement membrane network. Furthermore, expression of the laminin alpha 1-chain gene may be a regulatory element in determining cell differentiation. PMID:8609173

  17. Automatic recognition of falls in gait-slip training: Harness load cell based criteria.

    PubMed

    Yang, Feng; Pai, Yi-Chung

    2011-08-11

    Over-head-harness systems, equipped with load cell sensors, are essential to the participants' safety and to the outcome assessment in perturbation training. The purpose of this study was to first develop an automatic outcome recognition criterion among young adults for gait-slip training and then verify such criterion among older adults. Each of 39 young and 71 older subjects, all protected by safety harness, experienced 8 unannounced, repeated slips, while walking on a 7m walkway. Each trial was monitored with a motion capture system, bilateral ground reaction force (GRF), harness force, and video recording. The fall trials were first unambiguously indentified with careful visual inspection of all video records. The recoveries without balance loss (in which subjects' trailing foot landed anteriorly to the slipping foot) were also first fully recognized from motion and GRF analyses. These analyses then set the gold standard for the outcome recognition with load cell measurements. Logistic regression analyses based on young subjects' data revealed that the peak load cell force was the best predictor of falls (with 100% accuracy) at the threshold of 30% body weight. On the other hand, the peak moving average force of load cell across 1s period, was the best predictor (with 100% accuracy) separating recoveries with backward balance loss (in which the recovery step landed posterior to slipping foot) from harness assistance at the threshold of 4.5% body weight. These threshold values were fully verified using the data from older adults (100% accuracy in recognizing falls). Because of the increasing popularity in the perturbation training coupling with the protective over-head-harness system, this new criterion could have far reaching implications in automatic outcome recognition during the movement therapy. Copyright © 2011 Elsevier Ltd. All rights reserved.

  18. AUTOMATIC RECOGNITION OF FALLS IN GAIT-SLIP: A HARNESS LOAD CELL BASED CRITERION

    PubMed Central

    Yang, Feng; Pai, Yi-Chung

    2012-01-01

    Over-head-harness systems, equipped with load cell sensors, are essential to the participants’ safety and to the outcome assessment in perturbation training. The purpose of this study was to first develop an automatic outcome recognition criterion among young adults for gait-slip training and then verify such criterion among older adults. Each of 39 young and 71 older subjects, all protected by safety harness, experienced 8 unannounced, repeated slips, while walking on a 7-m walkway. Each trial was monitored with a motion capture system, bilateral ground reaction force (GRF), harness force and video recording. The fall trials were first unambiguously indentified with careful visual inspection of all video records. The recoveries without balance loss (in which subjects’ trailing foot landed anteriorly to the slipping foot) were also first fully recognized from motion and GRF analyses. These analyses then set the gold standard for the outcome recognition with load cell measurements. Logistic regression analyses based on young subjects’ data revealed that peak load cell force was the best predictor of falls (with 100% accuracy) at the threshold of 30% body weight. On the other hand, the peak moving average force of load cell across 1-s period, was the best predictor (with 100% accuracy) separating recoveries with backward balance loss (in which the recovery step landed posterior to slipping foot) from harness assistance at the threshold of 4.5% body weight. These threshold values were fully verified using the data from older adults (100% accuracy in recognizing falls). Because of the increasing popularity in the perturbation training coupling with the protective over-head-harness system, this new criterion could have far reaching implications in automatic outcome recognition during the movement therapy. PMID:21696744

  19. MTR BASEMENT. WORKERS (DON ALVORD AND CYRIL VAN ORDEN OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    MTR BASEMENT. WORKERS (DON ALVORD AND CYRIL VAN ORDEN OF PHILLIPS PETROLEUM CO.) POSE FOR GAMMA IRRADIATION EXPERIMENT IN MTR CANAL. CANS OF FOOD WILL BE LOWERED TO CANAL BOTTOM, WHERE SPENT MTR FUEL ELEMENTS EMIT GAMMA RADIATION. INL NEGATIVE NO. 11746. Unknown Photographer, 8/20/1954 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  20. Basement rocks of Halmahera, eastern Indonesia: Implications for the early history of the Philippine Sea

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hall, R.G.N.; Ballantyne, P.

    1990-06-01

    The oldest rocks known on Halmahera, eastern Indonesia, are petrologically and chemically similar to supra-subduction ophiolites and include boninitic volcanics resembling those dredged from the Marianas forearc. The age of the ophiolitic rocks is unknown; in east Halmahera they are overlain by Late Cretaceous and Eocene volcanics and associated sediments. Similar volcanics form the basement of western Halmahera. Plutonic rocks intruding the ophiolite and associated metamorphic rocks also yield Late Cretaceous to Eocene radiometric ages. The petrology and chemistry of the igneous rocks indicate an island arc origin. These rocks are locally overlain by shallow-water Eocene limestones and all aremore » overlain unconformably by Neogene sediments. The Halmahera basement rocks have many structural, petrological, and stratigraphic similarities to submarine plateaus of the southern and northern Philippine Sea and basement terranes of the eastern Philippines. The authors suggest that these similarities indicate the existence of an extensive region of Late Cretaceous and Eocene volcanism built upon probable Mesozoic ophiolitic basement. The resultant thickened crust was later fragmented by spreading in the West Philippine Sea Central Basin and backarc spreading in the Eastern Philippine Sea. It is difficult to reconcile the present distribution of these crustal fragments with a linear arc, but equally difficult to propose a simple alternative. A proto-Philippine archipelago, with short-lived arcs separated by small oceanic basins, may be the closest modern analog. The development of younger subduction zones has been influenced by the distribution of thickened crustal fragments as they have re-amalgamated since the Miocene.« less

  1. Network harness: bundles of routes in public transport networks

    NASA Astrophysics Data System (ADS)

    Berche, B.; von Ferber, C.; Holovatch, T.

    2009-12-01

    Public transport routes sharing the same grid of streets and tracks are often found to proceed in parallel along shorter or longer sequences of stations. Similar phenomena are observed in other networks built with space consuming links such as cables, vessels, pipes, neurons, etc. In the case of public transport networks (PTNs) this behavior may be easily worked out on the basis of sequences of stations serviced by each route. To quantify this behavior we use the recently introduced notion of network harness. It is described by the harness distribution P(r, s): the number of sequences of s consecutive stations that are serviced by r parallel routes. For certain PTNs that we have analyzed we observe that the harness distribution may be described by power laws. These power laws indicate a certain level of organization and planning which may be driven by the need to minimize the costs of infrastructure and secondly by the fact that points of interest tend to be clustered in certain locations of a city. This effect may be seen as a result of the strong interdependence of the evolutions of both the city and its PTN. To further investigate the significance of the empirical results we have studied one- and two-dimensional models of randomly placed routes modeled by different types of walks. While in one dimension an analytic treatment was successful, the two dimensional case was studied by simulations showing that the empirical results for real PTNs deviate significantly from those expected for randomly placed routes.

  2. Restraint harness performance during flight maneuvers: a parametric study.

    PubMed

    Du, Cheng-Fei; Liu, Xiao-Yu; Wang, Li-Zhen; Liu, Song-Yang; Fan, Yu-Bo

    2015-05-01

    Modern super agile fighter aircraft are capable of producing an increasing multiaxial acceleration environment which can adversely affect the pilot. An evaluation of the performance of the restraint system during flight maneuvers will benefit restraint designs and, thus, the safety of pilots. A finite element model of a mannequin with PCU-15/P harness restraint was used in this study to investigate how the factors, such as strap material stiffness, friction, and belt tension, affect the performance of restraint systems during impact along the -Gx, -Gy, and -Gz directions. The corresponding maximum displacement of the mannequin's torso was computed. The mannequin moved beyond 74 mm sideways. The change in friction coefficient (FC) from 0.1 to 0.4 decreased the displacement of the lower torso by less than 6.7%. The displacement of the torso decreased as the stiffness of the strap or tension increased. Displacement decreased by 9.3%, 6.0%, and 2.7% for the lower torso under the Gx impact, as the tightening force increased from 20 N to 80 N gradually. However, this changed slightly when the stiffness arrived at 1 E or the tension increased to 60 N. PCU-15/P harness has the poorest performance during side impact and friction plays an unimportant role in affecting its performance. The stiffness of the webbing used in the PCU-15/P harness is sufficiently high. The lap belt has more effect on limiting the movement of the pilot than the shoulder straps, and a tension of 60 N during the adjustment may be enough for conventional flight maneuvers.

  3. HARNESS END OF ELECTRIC TURBINE IN LOWER LEVEL OF HYDROELECTRIC ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    HARNESS END OF ELECTRIC TURBINE IN LOWER LEVEL OF HYDROELECTRIC POWER HOUSE - St. Lucie Canal, Lock No. 1, Hydroelectric Power House, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL

  4. PBF Reactor Building (PER620). Camera in second basement near subpile ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PBF Reactor Building (PER-620). Camera in second basement near sub-pile room (directly below reactor vessel). Door and penetrations lead to sub-pile room. Date: August 15, 1969. Photographer: Larry Page. INEEL negative no. 69-4310 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

  5. FLOOR PLAN OF MAIN PROCESSING BUILDING (CPP601) BASEMENT SHOWING PROCESS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FLOOR PLAN OF MAIN PROCESSING BUILDING (CPP-601) BASEMENT SHOWING PROCESS CORRIDOR AND EIGHTEEN CELLS. TO LEFT IS LABORATORY BUILDING (CPP-602). INL DRAWING NUMBER 200-0601-00-706-051981. ALTERNATE ID NUMBER CPP-E-1981. - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

  6. Accelerations and Passenger Harness Loads Measured in Full-Scale Light-Airplane Crashes

    NASA Technical Reports Server (NTRS)

    Eiband, A. Martin; Simpkinson, Scott H.; Black, Dugald O.

    1953-01-01

    Full-scale light-airplane crashes simulating stall-spin accidents were conducted to determine the decelerations to which occupants are exposed and the resulting harness forces encountered in this type of accident. Crashes at impact speeds from 42 to 60 miles per hour were studied. The airplanes used were of the familiar steel-tube, fabric-covered, tandem, two-seat type. In crashes up to an impact speed of 60 miles per hour, crumpling of the forward fuselage structure prevented the maximum deceleration at the rear-seat location from exceeding 26 to 33g. This maximum g value appeared independent of the impact speed. Restraining forces in the seatbelt - shoulder-harness combination reached 5800 pounds. The rear-seat occupant can survive crashes of the type studied at impact speeds up to 60 miles per hour, if body movement is restrained by an adequate seatbelt-shoulder-harness combination so as to prevent injurious contact with obstacles normally present in the cabin. Inwardly collapsing cabin structure, however, is a potential hazard in the higher-speed crashes.

  7. Precambrian basement geology of North and South Dakota.

    USGS Publications Warehouse

    Klasner, J.S.; King, E.R.

    1986-01-01

    Combined analysis of drill-hole, gravity and magnetic data indicates that the Precambrian rocks in the basement of the Dakotas may be divided into a series of lithotectonic terrains. On the basis of an analysis of geological and geophysical data in the Dakotas and from the surrounding states and Canada, it is shown how the exposed Precambrian rocks of the adjacent shield areas project into the study area. Brief comments are made on the tectonic implications of this study. Geological and geophysical characteristics of 11 terrains are tabulated. -P.Br.

  8. TESTING OF INDOOR RADON REDUCTION TECHNIQUES IN BASEMENT HOUSES HAVING ADJOINING WINGS

    EPA Science Inventory

    The report gives results of tests of indoor radon reduction techniques in 12 existing Maryland houses, with the objective of determining when basement houses with adjoining wings require active soil depressurization (ASD) treatment of both wings, and when treatment of the basemen...

  9. Metasomatic tourmalinite formation along basement-cover decollements, Orobic Alps, Italy

    USGS Publications Warehouse

    Slack, J.F.; Passchier, C.W.; Zhang, J.S.

    1996-01-01

    Cryptocrystalline tourmalinites that occur discontinuously for ???30 km along basement-cover de??collements of the Orohic Alps (Italy) formed by the metasomatism of aluminous cataclasites derived from Permian conglomerates and/or feldspathic sandstones. Using Al as an immobile element monitor, calculations show that the majority of tourmalinites in the region formed through the addition of moderate to significant amounts of B, Mg, Na, Sr, and Be, and the loss of moderate to significant Mn, Ca, K, P, Rb, Ba, and Cr; minor Si, Ti, V, light REE, and Eu also were lost. Data tor relatively immobile Al, Zr, Th, Sc, Nb, and heavy REE indicate that, on average, these tourmalinites formed through ???12% net mass loss assuming an original conglomerate protolith, or through ???7% net mass loss assuming a sandstone protolith. The B and other introduced constituents in the tourmalinites were deposited by hydrothermal fluids focused along and near basement-cover de??collements. These fluids, believed to be associated with late Hercynian felsic magmatism, probably are related to fluids that formed the tourmaline-rich U-Mo-Zn deposits at the nearby Novazza mine and the U-Zn deposits at the nearby Val Vedello mine.

  10. Paleohighs and Paleolows in the Basement Rocks of the Eastern Gulf of Mexico

    NASA Astrophysics Data System (ADS)

    Robinson, D.; Weislogel, A. L.

    2017-12-01

    The Eastern Gulf of Mexico has topography on the basement rocks composed of igneous and metamorphic rocks as well as some sedimentary rocks underneath a relatively thin salt layer with 3-6 km of topography relief. Paleohighs from south to north include Sarasota Arch, Middle Ground Arch/Southern Platform, Pensacola Arch, Conecuh Ridge Complex, Baldwin High, Wiggins Arch and Choctaw Ridge Complex. Paleolows from south to north include South Florida Basin, Tampa Embayment, Apalachicola Basin/Desoto Canyon Salt Basin, Conecuh Embayment, Manila Embayment and the Mississippi Interior Salt Basin. The topography on the basement is a result of several collisions between Laurentian and Gondwana to produce Pangea with final suturing during Pennsylvanian time and also from extension in Late Triassic to Early Cretaceous time as a result of the opening of the Gulf and rotation of Yucatan. Heterogeneities related to previous collisions may have also factored into producing these paleohighs and paleolows. A series of grabens and half-grabens, trending northeast-southwest from northwest-southeast directed extension and with the sedimentary rocks, exist on the continents and appear to be present in the offshore under the salt. We know the paleolows were depositional pathways to funnel sediments from onshore to offshore via water and wind in Jurassic and maybe Cretaceous times. Many tectonic models call for the paleohighs and paleolows to be structurally controlled; however, finding the faults called upon to control the "horst and graben" structures is challenging. We present data from several seismic studies that questions the idea that these paleohighs and paleolows are the result of horst and graben extension. Half grabens exist in the offshore with graben bounding faults northeast-southwest; however, down is to the north instead of the anticipated down to the south. Instead, the basement paleohighs and paleolows in the offshore Eastern Gulf of Mexico may be the result of

  11. Hydrothermal Circulation Within and Between Basement Outcrops on a Young Ridge Flank: Numerical Models and Thermal Constraints

    NASA Astrophysics Data System (ADS)

    Hutnak, M.; Fisher, A. T.; Stauffer, P.; Gable, C. W.

    2005-12-01

    We use two-dimensional, finite-element models of coupled heat and fluid flow to investigate local and large-scale heat and fluid transport around and between basement outcrops on a young ridge flank. System geometries and properties are based on observations and measurements on the 3.4-3.6 Ma eastern flank of the Juan de Fuca Ridge. A small area of basement exposure (Baby Bare outcrop) experiences focused hydrothermal discharge, whereas a much larger feature (Grizzly Bare outcrop) 50 km to the south is a site of hydrothermal recharge. Observations of seafloor heat flow, subseafloor pressures, and basement fluid geochemistry at and near these outcrops constrain acceptable model results. Single-outcrop simulations suggest that local convection alone (represented by a high Nusselt number proxy) cannot explain the near-outcrop heat flow patterns; rapid through-flow is required. Venting of at least 5 L/s through the smaller outcrop, a volumetric flow rate consistent with earlier estimates based on plume and outcrop measurements, is needed to match seafloor heat flow patterns. Heat flow patterns are more variable and complex near the larger, recharging outcrop. Simulations that include 5-20 L/s of recharge through this feature can replicate first-order trends in the data, but small-scale variations are likely to result from heterogeneous flow paths and vigorous, local convection. Two-outcrop simulations started with a warm hydrostatic initial condition, based on a conductive model, result in rapid fluid flow from the smaller outcrop to the larger outcrop, inconsistent with observations. Flow can be sustained in the opposite (correct) direction if it is initially forced, which generates a hydrothermal siphon between the two features. Free flow simulations maintain rapid circulation at rates consistent with observations (specific discharge of m/yr to tens of m/yr), provided basement permeability is on the order of 10-10 m2 or greater. Lateral flow rates scale inversely

  12. Influence of pre-existing basement faults on the structural evolution of the Zagros Simply Folded belt: 3D numerical modelling

    NASA Astrophysics Data System (ADS)

    Ruh, Jonas B.; Gerya, Taras

    2015-04-01

    The Simply Folded Belt of the Zagros orogen is characterized by elongated fold trains symptomatically defining the geomorphology along this mountain range. The Zagros orogen results from the collision of the Arabian and the Eurasian plates. The Simply Folded Belt is located southwest of the Zagros suture zone. An up to 2 km thick salt horizon below the sedimentary sequence enables mechanical and structural detachment from the underlying Arabian basement. Nevertheless, deformation within the basement influences the structural evolution of the Simply Folded Belt. It has been shown that thrusts in form of reactivated normal faults can trigger out-of-sequence deformation within the sedimentary stratigraphy. Furthermore, deeply rooted strike-slip faults, such as the Kazerun faults between the Fars zone in the southeast and the Dezful embayment and the Izeh zone, are largely dispersing into the overlying stratigraphy, strongly influencing the tectonic evolution and mechanical behaviour. The aim of this study is to reveal the influence of basement thrusts and strike-slip faults on the structural evolution of the Simply Folded Belt depending on the occurrence of intercrustal weak horizons (Hormuz salt) and the rheology and thermal structure of the basement. Therefore, we present high-resolution 3D thermo-mechnical models with pre-existing, inversively reactivated normal faults or strike-slip faults within the basement. Numerical models are based on finite difference, marker-in-cell technique with (power-law) visco-plastic rheology accounting for brittle deformation. Preliminary results show that deep tectonic structures present in the basement may have crucial effects on the morphology and evolution of a fold-and-thrust belt above a major detachment horizon.

  13. Difficulties in differentiating thin basement membrane disease from Alport syndrome.

    PubMed

    Żurawski, Jakub; Burchardt, Paweł; Seget, Monika; Moczko, Jerzy; Woźniak, Aldona; Grochowalski, Marcin; Salwa-Żurawska, Wiesława

    We examined a group of 83 patients (57 children and 26 adults) with thin basement membrane disease and 17 patients with Alport syndrome. We compared the clinical data and, above all, the morphological patterns of both disease entities, with particular focus on not very advanced changes which might lead to a misdiagnosis due to the non-detection of the early stages of Alport syndrome.

  14. 4. INTERIOR VIEW OF BASEMENT. CENTRAL LINE SHAFTING RUNNING NORTHSOUTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. INTERIOR VIEW OF BASEMENT. CENTRAL LINE SHAFTING RUNNING NORTH-SOUTH IS IN PLACE; AT RIGHT IS A PRESS FOR WORKING THE ALUMINUM SHEETS; E. W. BLISS CO. OF BROOKLYN, NEW YORK, MANUFACTURED THE PRESS. MACHINERY ORIGINALLY POWERED BY OVERHEAD BELTS CONNECTED TO CENTRAL LINE SHAFTS; BY ABOUT THE 1940s THE MACHINERY WAS ELECTRICALLY POWERED. - Illinois Pure Aluminum Company, 109 Holmes Street, Lemont, Cook County, IL

  15. Microbial diversity within Juan de Fuca ridge basement fluids sampled from oceanic borehole observatories

    NASA Astrophysics Data System (ADS)

    Jungbluth, S.; Bowers, R.; Lin, H.; Hsieh, C.; Cowen, J. P.; Rappé, M.

    2012-12-01

    Three generations of sampling and instrumentation platforms known as Circulation Obviation Retrofit Kit (CORK) observatories affixed to Ocean Drilling Program (ODP) and Integrated Ocean Drilling Program (IODP) boreholes are providing unrivaled access to fluids originating from 1.2-3.5 million-years (Myr) old basaltic crust of the eastern flank of the Juan de Fuca ridge. Borehole fluid samples obtained via a custom seafloor fluid pumping and sampling system coupled to CORK continuous fluid delivery lines are yielding critical insights into the biogeochemistry and nature of microbial life inhabiting the sediment-covered basement environment. Direct microscopic enumeration revealed microbial cell abundances that are 2-41% of overlying bottom seawater. Snapshots of basement fluid microbial diversity and community structure have been obtained through small subunit ribosomal RNA (SSU rRNA) gene cloning and sequencing from five boreholes that access a range of basement ages and temperatures at the sediment-basement interface. SSU rRNA gene clones were derived from four different CORK installations (1026B, 1301A, 1362A, and 1362B) accessing relatively warmer (65°C) and older (3.5 Myr) ridge flank, and one location (1025C) accessing relatively cooler (39°C) and younger (1.2 Myr) ridge flank, revealing that warmer basement fluids had higher microbial diversity. A sampling time-series collected from borehole 1301A has revealed a microbial community that is temporally variable, with the dominant lineages changing between years. Each of the five boreholes sampled contained a unique microbial assemblage, however, common members are found from both cultivated and uncultivated lineages within the archaeal and bacterial domains, including meso- and thermophilic microbial lineages involved with sulfur cycling (e.g Thiomicrospira, Sulfurimonas, Desulfocapsa, Desulfobulbus). In addition, borehole fluid environmental gene clones were also closely related to uncultivated lineages

  16. PBF Reactor Building (PER620). Cubicle 10 area in basement. Highdensity ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PBF Reactor Building (PER-620). Cubicle 10 area in basement. High-density shielding bricks will protect personnel from radiation coming from in-pile-tube coolant and blowdown tank. Photographer: John Capek. Date: January 26, 1970. INEEL negative no. 70-348 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

  17. ETR BUILDING, TRA642, INTERIOR. BASEMENT. CORRIDOR ALONG WEST WALL OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ETR BUILDING, TRA-642, INTERIOR. BASEMENT. CORRIDOR ALONG WEST WALL OF BUILDING, WHICH IS AT RIGHT OF VIEW. AUDIO ALARM IS ALONG WALL AT RIGHT. CAMERA FACES SOUTH. INL NEGATIVE NO. HD46-30-1. Mike Crane, Photographer, 2/2005 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  18. LPT. Low power test (TAN640) interior. Basement level. Camera facing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    LPT. Low power test (TAN-640) interior. Basement level. Camera facing north. Cable trays and conduit cross tunnel between critical experiment cell and critical experiment control room. Construction 93% complete. Photographer: Jack L. Anderson. Date: October 23, 1957. INEEL negative no. 57-5339 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  19. Conceptual Model for Basement and Surface Structure Relationships in an Oblique Collision, Sawtooth Range, MT

    NASA Astrophysics Data System (ADS)

    Palu, J. M.; Burberry, C. M.

    2014-12-01

    The reactivation potential of pre-existing basement structures affects the geometry of subsequent deformation structures. A conceptual model depicting the results of these interactions can be applied to multiple fold-thrust systems and lead to valuable deformation predictions. These predictions include the potential for hydrocarbon traps or seismic risk in an actively deforming area. The Sawtooth Range, Montana, has been used as a study area. A model for the development of structures close to the Augusta Syncline in the Sawtooth Range is being developed using: 1) an ArcGIS map of the basement structures of the belt based on analysis of geophysical data indicating gravity anomalies and aeromagnetic lineations, seismic data indicating deformation structures, and well logs for establishing lithologies, previously collected by others and 2) an ArcGIS map of the surface deformation structures of the belt based on interpretation of remote sensing images and verification through the collection of surface field data indicating stress directions and age relationships, resulting in a conceptual model based on the understanding of the interaction of the two previous maps including statistical correlations of data and development of balanced cross-sections using Midland Valley's 2D/3D Move software. An analysis of the model will then indicate viable deformation paths where prominent basement structures influenced subsequently developed deformation structures and reactivated faults. Preliminary results indicate that the change in orientation of thrust faults observed in the Sawtooth Range, from a NNW-SSE orientation near the Gibson Reservoir to a WNW-ESE trend near Haystack Butte correlates with pre-existing deformation structures lying within the Great Falls Tectonic Zone. The Scapegoat-Bannatyne trend appears to be responsible for this orientation change and rather than being a single feature, may be composed of up to 4 NE-SW oriented basement strike-slip faults. This

  20. Harnessing the crowd to accelerate molecular medicine research.

    PubMed

    Smith, Robert J; Merchant, Raina M

    2015-07-01

    Crowdsourcing presents a novel approach to solving complex problems within molecular medicine. By leveraging the expertise of fellow scientists across the globe, broadcasting to and engaging the public for idea generation, harnessing a scalable workforce for quick data management, and fundraising for research endeavors, crowdsourcing creates novel opportunities for accelerating scientific progress. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. ER stress and basement membrane defects combine to cause glomerular and tubular renal disease resulting from Col4a1 mutations in mice

    PubMed Central

    Jones, Frances E.; Bailey, Matthew A.; Murray, Lydia S.; Lu, Yinhui; McNeilly, Sarah; Schlötzer-Schrehardt, Ursula; Lennon, Rachel; Sado, Yoshikazu; Brownstein, David G.; Mullins, John J.; Kadler, Karl E.; Van Agtmael, Tom

    2016-01-01

    ABSTRACT Collagen IV is a major component of basement membranes, and mutations in COL4A1, which encodes collagen IV alpha chain 1, cause a multisystemic disease encompassing cerebrovascular, eye and kidney defects. However, COL4A1 renal disease remains poorly characterized and its pathomolecular mechanisms are unknown. We show that Col4a1 mutations in mice cause hypotension and renal disease, including proteinuria and defects in Bowman's capsule and the glomerular basement membrane, indicating a role for Col4a1 in glomerular filtration. Impaired sodium reabsorption in the loop of Henle and distal nephron despite elevated aldosterone levels indicates that tubular defects contribute to the hypotension, highlighting a novel role for the basement membrane in vascular homeostasis by modulation of the tubular response to aldosterone. Col4a1 mutations also cause diabetes insipidus, whereby the tubular defects lead to polyuria associated with medullary atrophy and a subsequent reduction in the ability to upregulate aquaporin 2 and concentrate urine. Moreover, haematuria, haemorrhage and vascular basement membrane defects confirm an important vascular component. Interestingly, although structural and compositional basement membrane defects occurred in the glomerulus and Bowman's capsule, no tubular basement membrane defects were detected. By contrast, medullary atrophy was associated with chronic ER stress, providing evidence for cell-type-dependent molecular mechanisms of Col4a1 mutations. These data show that both basement membrane defects and ER stress contribute to Col4a1 renal disease, which has important implications for the development of treatment strategies for collagenopathies. PMID:26839400

  2. Removal of the basement membrane enhances corneal wound healing.

    PubMed

    Pal-Ghosh, Sonali; Pajoohesh-Ganji, Ahdeah; Tadvalkar, Gauri; Stepp, Mary Ann

    2011-12-01

    Recurrent corneal erosions are painful and put patients' vision at risk. Treatment typically begins with debridement of the area around the erosion site followed by more aggressive treatments. An in vivo mouse model has been developed that reproducibly induces recurrent epithelial erosions in wild-type mice spontaneously within two weeks after a single 1.5 mm corneal debridement wound created using a dulled-blade. This study was conducted to determine whether 1) inhibiting MMP9 function during healing after dulled-blade wounding impacts erosion development and 2) wounds made with a rotating-burr heal without erosions. Oral or topical inhibition of MMPs after dulled-blade wounding does not improve healing. Wounds made by rotating-burr heal with significantly fewer erosions than dulled-blade wounds. The localization of MMP9, β4 integrin and basement membrane proteins (LN332 and type VII collagen), immune cell influx, and reinnervation of the corneal nerves were compared after both wound types. Rotating-burr wounds remove the anterior basement membrane centrally but not at the periphery near the wound margin, induce more apoptosis of corneal stromal cells, and damage more stromal nerve fibers. Despite the fact that rotating-burr wounds do more damage to the cornea, fewer immune cells are recruited and significantly more wounds resolve completely. Copyright © 2011 Elsevier Ltd. All rights reserved.

  3. Comparison among GPR measurements and ultrasonic tomographies with different inversion strategies applied to the basement of an ancient egyptian sculpture.

    NASA Astrophysics Data System (ADS)

    Sambuelli, Luigi; Bohm, Gualtiero; Capizzi, Patrizia; Cardarelli, Ettore; Cosentino, Pietro; D'Onofrio, Laurent; Marchisio, Mario

    2010-05-01

    By the late 2008 one of the most important pieces of the "Museo delle Antichità Egizie" in Turin, the sculpture of the Pharaoh with god Amun, was planned to be one of the masterpieces of a travelling exhibition in Japan. The "Fondazione Museo delle Antichità Egizie di Torino", managing the museum, was concerned with the integrity of the basement of the statue which actually presents visible signs of restorations dating back to the early IXX century. The questions put by the museum managers were to estimate the internal extension of some visible fractures, to search for unknown internal ones and to provide information about the overall mechanical strength of the basement. In order to tackle the first and second questions a GPR reflection survey of the basement along three sides was performed and the results were assembled in a 3D rendering. As far as the third question is concerned, two parallel, horizontal ultrasonic 2D tomographies across the basement were made with a source-receiver layout able to acquire, for each section, 723 ultrasonic signals correspondent to different transmitter and receiver positions. The ultrasonic tomographic data were inverted using different software based upon different algorithms. The obtained velocity images were then compared with the GPR results and with the visible joints on the basement. A critical analysis of the comparisons is finally presented.

  4. Provenance of Austroalpine basement metasediments: tightening up Early Palaeozoic connections between peri-Gondwanan domains of central Europe and Northern Africa

    NASA Astrophysics Data System (ADS)

    Siegesmund, S.; Oriolo, S.; Heinrichs, T.; Basei, M. A. S.; Nolte, N.; Hüttenrauch, F.; Schulz, B.

    2018-03-01

    New U-Pb and Lu-Hf detrital zircon data together with whole-rock geochemical and Sm-Nd data were obtained for paragneisses of the Austroalpine basement south of the Tauern Window. Geochemically immature metasediments of the Northern-Defereggen-Petzeck (Ötztal-Bundschuh nappe system) and Defereggen (Drauzug-Gurktal nappe system) groups contain zircon age populations which indicate derivation mainly from Pan-African orogens. Younger, generally mature metasediments of the Gailtal Metamorphic Basement (Drauzug-Gurktal nappe system), Thurntaler Phyllite Group (Drauzug-Gurktal nappe system) and Val Visdende Formation (South Alpine Basement) were possibly derived from more distant sources. Their significantly larger abundances of pre-Pan-African zircons record a more advanced stage of downwearing of the Pan-African belts and erosion of older basement when the Austroalpine terrane was part of the Early Palaeozoic Northern Gondwana passive margin. Most zircon age spectra are dominated by Ediacaran sources, with lesser Cryogenian, Tonian and Stenian contributions and subordinate Paleoproterozoic and Neoarchean ages. These age patterns are similar to those recorded by Cambro-Ordovician sedimentary sequences in northeastern Africa between Libya and Jordan, and in some pre-Variscan basement inliers of Europe (e.g. Dinarides-Hellenides, Alboran microplate). Therefore, the most likely sources seem to be in the northeastern Saharan Metacraton and the Northern Arabian-Nubian Shield (Sinai), further supported by whole-rock Sm-Nd and zircon Lu-Hf data.

  5. Embedding human annoyance rate models in wireless smart sensors for assessing the influence of subway train-induced ambient vibration

    NASA Astrophysics Data System (ADS)

    Sun, Ke; Zhang, Wei; Ding, Huaping; Kim, Robin E.; Spencer, Billie F., Jr.

    2016-10-01

    The operation of subway trains induces ambient vibrations, which may cause annoyance and other adverse effects on humans, eventually leading to physical, physiological, and psychological problems. In this paper, the human annoyance rate (HAR) models, used to assess the human comfort under the subway train-induced ambient vibrations, were deduced and the calibration curves for 5 typical use circumstances were addressed. An autonomous measurement system, based on the Imote2, wireless smart sensor (WSS) platform, plus the SHM-H, high-sensitivity accelerometer board, was developed for the HAR assessment. The calibration curves were digitized and embedded in the computational core of the WSS unit. Experimental validation was conducted, using the developed system on a large underground reinforced concrete frame structure adjoining the subway station. The ambient acceleration of both basement floors was measured; the embedded computation was implemented and the HAR assessment results were wirelessly transmitted to the central server, all by the WSS unit. The HAR distributions of the testing areas were identified, and the extent to which both basements will be influenced by the close-up subway-train’s operation, in term of the 5 typical use circumstances, were quantitatively assessed. The potential of the WSS-based autonomous system for the fast environment impact assessment of the subway train-induced ambient vibration was well demonstrated.

  6. Late Vendian Complexes in the Structure of Metamorphic Basement of the Fore Range Zone, Greater Caucasus

    NASA Astrophysics Data System (ADS)

    Kamzolkin, V. A.; Latyshev, A. V.; Vidyapin, Yu. P.; Somin, M. L.; Smul'skaya, A. I.; Ivanov, S. D.

    2018-05-01

    The paper presents new data on the composition, age, and relationships (with host and overlying deposits) of intrusive rocks in the basement of the Fore Range zone (Greater Caucasus), in the Malaya Laba River Basin. The evolutionary features of intrusive units located within the Blyb metamorphic complex are described. It is shown for the first time that the lower levels of this complex are, in a structural sense, outcrops of the Late Vendian basement. The basement is composed of the Balkan Formation and a massif of quartz metadiorites that intrudes it; for the rocks of this massif, ages ranging from 549 ± 7.4 to 574.1 ± 6.7 Ma are obtained for three U-Pb datings by the SHRIMP-II method. The Herzyinan magmatic event is represented by a group of granodiorite intrusions penetrating the Blyb complex on a series of faults extending along its boundary with the Main Range zone. The obtained estimate for the U-Pb age of one of the intrusions (319 ± 3.8 Ma) corresponds to the end of the Serpukhovian stage of the Early Carboniferous.

  7. ETR, TRA642. ON BASEMENT FLOOR. REACTOR VESSEL WILL BE PLACED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ETR, TRA-642. ON BASEMENT FLOOR. REACTOR VESSEL WILL BE PLACED WITHIN THE INNER METAL FORM. WHEN CONCRETE IS POURED OUTSIDE THIS FORM, CONDUIT HOLES WILL BE PRESERVE SPACE THROUGH HOLES. INL NEGATIVE NO. 56-1507. Jack L. Anderson, Photographer, 5/8/1956 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  8. MTR WING, TRA604. BASEMENT FLOOR PLAN. FIREPROOF RECORD ROOM BELOW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    MTR WING, TRA-604. BASEMENT FLOOR PLAN. FIRE-PROOF RECORD ROOM BELOW COUNTING ROOM. HEATING AND COOLING EQUIPMENT. UNSPECIFIED EXPANSION AREA ALONG WEST WALL. BLAW-KNOX 3150-4-1, 7/1950. INL INDEX NO. 531-0604-00-098-100007, REV. 1. - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  9. 28. PUMP/ENGINE ROOM OFF THE BASEMENT OF MILL NO. 1. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    28. PUMP/ENGINE ROOM OFF THE BASEMENT OF MILL NO. 1. ENGINE PLATFORM IS SEEN BEHIND PUMP. THIS AMERICAN MOISTURE CO. PUMP WAS USED TO HUMIDIFY UPPER FLOORS OF MILL. NOTE TANK TO LEFT, UNKNOWN USE. NOTHING IN THIS ROOM HAS BEEN USED SINCE 1945. - Prattville Manufacturing Company, Number One, 242 South Court Street, Prattville, Autauga County, AL

  10. 146. View of oil filter room in basement (Room B1) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    146. View of oil filter room in basement (Room B-1) where oil used in lubrication in generator room is cleaned and recycled. The two tanks in the foreground each have capacities of 2,100 gallons. Photo by Jet Lowe, HAER, 1989. - Puget Sound Power & Light Company, White River Hydroelectric Project, 600 North River Avenue, Dieringer, Pierce County, WA

  11. Reliability and Validity of the Zephyr[TM] BioHarness[TM] to Measure Respiratory Responses to Exercise

    ERIC Educational Resources Information Center

    Hailstone, Jono; Kilding, Andrew E.

    2011-01-01

    The Zephyr[TM] BioHarness[TM] (Zephyr Technology, Auckland, New Zealand) is a wireless physiological monitoring system that has the ability to measure respiratory rate unobtrusively. However, the ability of the BioHarness[TM] to accurately and reproducibly determine respiratory rate across a range of intensities is currently unknown. The aim of…

  12. Basement Fracturing and Weathering On- and Offshore Norway - Genesis, Age, and Landscape Development

    NASA Astrophysics Data System (ADS)

    Knies, J.; van der Lelij, R.; Faust, J.; Scheiber, T.; Broenner, M.; Fredin, O.; Mueller, A.; Viola, G.

    2014-12-01

    Saprolite remnants onshore Scandinavia have been investigated only sporadically. The nature and age of the deeply weathered material thus remains only loosely constrained. The type and degree of weathering of in situ weathered soils are indicative of the environmental conditions during their formation. When external forcing changes, properties related to previous weathering conditions are usually preserved, for example in clay mineral assemblages. By constraining the age and rate of weathering onshore and by isotopically dating selected faults determined to be intimately linked to weathered basement blocks, the influence of climate development, brittle deformation and landscape processes on weathering can be quantified. The "BASE" project aims to establish a temporal and conceptual framework for brittle tectonics, weathering patterns and landscape evolution affecting the basement onshore and offshore Norway. We will study the formation of saprolite in pre-Quaternary times, the influence of deep weathering on landscape development and establish a conceptual structural template of the evolution of the brittle deformational features that are exposed on onshore (weathered) basement blocks. Moreover, saprolitic material may have been eroded and preserved along the Norwegian continental margin during Cenozoic times. By studying both the onshore remnants and offshore erosional products deposited during periods of extreme changes of climate and tectonic boundary conditions (e..g Miocene-Pliocene), new inferences on the timing and controlling mechanisms of denudation, and on the relevance of deep weathering on Late Cenozoic global cooling can be drawn.

  13. 10. VIEW OF BASEMENT, LOOKING NORTHEAST. AT LEFT CENTER IS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. VIEW OF BASEMENT, LOOKING NORTHEAST. AT LEFT CENTER IS A 'BISON' CORN CRACKER (Wolf Co., Champ, Pennsylvania), DESIGNED TO CRACK KERNEL CORN. AT LEFT IS A 'EUREKA' CLEANER (S. Howe Co., Silver Creek, New York), WHOSE RECIPROCATING SIEVES REMOVED COARSE FOREIGN MATERIAL FROM WHEAT BEFORE MAKING FLOUR. Photographer: Jet T. Lowe, 1985 - Alexander's Grist Mill, Lock 37 on Ohio & Erie Canal, South of Cleveland, Valley View, Cuyahoga County, OH

  14. MTR BASEMENT. DOORWAY TO SOURCE STORAGE VAULT IS AT CENTER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    MTR BASEMENT. DOORWAY TO SOURCE STORAGE VAULT IS AT CENTER OF VIEW; TO DECONTAMINATION ROOM, AT RIGHT. PART OF MAZE ENTRY IS VISIBLE INSIDE VAULT DOORWAY. INL NEGATIVE NO. 7763. Unknown Photographer, photo was dated as 3/30/1953, but this was probably an error. The more likely date is 3/30/1952. - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  15. 6. INTERIOR VIEW OF BASEMENT OF CA. 1948 FACTORY ADDITION, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. INTERIOR VIEW OF BASEMENT OF CA. 1948 FACTORY ADDITION, WITH REINFORCED CONCRETE FRAME AND FLOOR OF REINFORCED CONCRETE TEE-BEAMS, LOOKING NORTH. AT LEFT IS DEEP DRAW, HEAVY PRESS MANUFACTURED BY E. W. BLISS CO., BROOKLYN, NEW YORK. PRESS #3-1/2 B, PATENTED BY E. W. BLISS CO., 1893. MANUFACTURERS PLATE INDICATES PRESS DATES FROM 1920. - Illinois Pure Aluminum Company, 109 Holmes Street, Lemont, Cook County, IL

  16. Manufacturing and quality control of interconnecting wire harnesses, Volume 2

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Interconnecting wire harnesses defined in the design standard are considered, including type 4, open bundle (not enclosed). Knowledge gained through experience on the Saturn 5 program coupled with recent advances in techniques, materials, and processes was incorporated into the document.

  17. Basement of Structure, Main Power and Design Parameters of Mechanism of Removing Sections of Mechanized Sets of Knife Plane Installation

    NASA Astrophysics Data System (ADS)

    Sysoev, N. I.; Turuk, Yu V.; Kolesnichenko, I. Y.; Lugantsev, B. B.

    2017-10-01

    The reasons for the failure of the pitch stability of the knife-plane installation due to the action of extreme effort in the plane of the seam from the conveyor side on the mechanism of removing sections of mechanized sets are shown. The technique for determining this effort is presented. The constructions of the adaptive mechanisms of the removing sections of mechanized sets with the basements of catamaran type, in the constrictions of which elastic elements (rods) are used, are considered. The constructions of the mechanism of removing a section of the mechanized set with the basement of catamaran type in which the stock of the hydraulic jack is connected with the band loop through the movable rods intermediate basement with a link are worked out. The intermediate basement unloads the stock of the hydraulic jack of the moving installation from the side curving efforts, caused by the action of lateral forces in the plane of the seam on the conveyor side. It increases the reliability and efficiency of work of the knife plane mechanized complex.

  18. Intraplate deformation on north-dipping basement structures in the Northern Gawler Craton, Australia: reactivation of original terrane boundaries or later intra-cratonic thrusts?

    NASA Astrophysics Data System (ADS)

    Baines, G.; Giles, D.; Betts, P. G.; Backé, G.

    2007-12-01

    Multiple intraplate orogenic events have deformed Neoproterozoic to Carboniferous sedimentary sequences that cover the Archean to Mesoproterozoic basement of the northern Gawler Craton, Australia. These intraplate orogenies reactivated north-dipping basement penetrating faults that are imaged on seismic reflection profiles. These north-dipping structures pre-date Neoproterozoic deposition but their relationships to significant linear magnetic and gravity anomalies that delineate unexposed Archean to Early Mesoproterozoic basement terranes are unclear. The north-dipping structures are either terrane boundaries that formed during continental amalgamation or later faults, which formed during a mid- to late-Mesoproterozoic transpressional orogeny and cross-cut the original lithological terrane boundaries. We model magnetic and gravity data to determine the 3D structure of the unexposed basement of the northern Gawler Craton. These models are constrained by drill hole and surface observations, seismic reflection profiles and petrophysical data, such that geologically reasonable models that can satisfy the data are limited. The basement structures revealed by this modelling approach constrain the origin and significance of the north-dipping structures that were active during the later intraplate Petermann, Delamerian and Alice Springs Orogenies. These results have bearing on which structures are likely to be active during present-day intraplate deformation in other areas, including, for example, current seismic activity along similar basement structures in the Adelaide "Geosyncline".

  19. Proximity of Wastewater Disposal and Hydraulic Fracturing to Crystalline Basement Affects the Likelihood of Induced Seismicity in the Central and Eastern United States

    NASA Astrophysics Data System (ADS)

    Brudzinski, M.; Skoumal, R.; Currie, B.

    2016-12-01

    Over the past decade, the dramatic rise in seismicity in the central and eastern US has been attributed to industry operations associated with wastewater injection and hydraulic fracturing. While most of the observed seismicity has occurred in sedimentary basins that have experienced overall increases in oil and gas development (e.g. the Anadarko and Ft. Worth basins), other basins with similar activity (e.g. the Williston and northern Appalachian basins) have experienced very little, if any, induced seismicity. While hydro-geomechanical modeling indicates that induced seismicity may be related to the proximity of critically stressed faults in the crystalline basement, recent studies have found fluid injection rate to be the dominant factor controlling induced seismicity. To test these interpretations we evaluated water disposal and well completion records from the Appalachian, Illinois, and Williston basins, and compared them with induced seismic sequences identified through seismic template matching of all cataloged earthquakes in these regions. Our results indicate a strong correspondence between induced seismic events and the proximity of subsurface wastewater injection/hydraulic fracturing targets to crystalline basement rocks. For example, in the northern Appalachian Basin, of the >20 identified induced seismic sequences, all but two were associated with injection/completion targets located at depths within 1 km of the basement. In parts of the basin where target intervals are at depths >1 km from basement, induced events have been recorded only in proximity to basement-involved faults. In addition, in the Williston Basin most disposal interval/hydraulic fracturing targets are >1 km above the crystalline basement which may explain the lack of induced seismic events in the region despite high rate fluid injection. Collectively, the results of our investigation suggest that proximity to basement is an important variable in considering the likelihood of induced

  20. 42 CFR 84.173 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Harnesses; installation and construction; minimum... SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE... construction; minimum requirements. (a) Each respirator shall, where necessary, be equipped with a suitable...

  1. Basement structure based on gravity anomaly in the northern Noto peninsula, Central Japan

    NASA Astrophysics Data System (ADS)

    Mizubayashi, T.; Sawada, A.; Hamada, M.; Hiramatsu, Y.; Honda, R.

    2012-12-01

    Upper crustal block structures are usually defined by using surface information, such as geological and morphological data. The northern Noto Peninsula, central Japan, is divided into four geological block structures from tectonic geomorphologic perspectives (Ota and Hirakawa, 1979). This division is based on the surface crustal movement. To image the geological blocks three-dimensionally, it is necessary to construct a subsurface structure model. Gravity survey can clarify the detailed subsurface structure with dense gravity measurement. From the detailed Bouguer anomalies in the northwestern Noto Peninsula, Honda et al. (2008) suggested that the rupture size of the 2007 Noto Hanto earthquake was constrained by the geological block structures. Hiramatsu et al. (2008) also suggested the active faults on the seafloor, such as the source fault of the 2007 Noto Hanto earthquake plays a major role for the formation of the geological block structures. In this study, we analyze subsurface density structure based on the Bouguer anomaly and estimate the distribution of basement depth in the northern Noto Peninsula. We focus the relationship among the basement depth, the block structures and the active faults on the seafloor and discuss the block movement in the northern Noto Peninsula. We compiled the data measured and published previously (Gravity Database of Southwest Japan, 2001; Geological survey of Japan, 2004; Geographical survey institute of Japan, 2006; The Gravity Research Group in Southwest Japan, 2001; Komazawa and Okuma, 2010; Hokuriku electric power Co. Ltd., undisclosed) and calculated Bouguer anomaly in the northern Noto Peninsula. Based on this Bouguer anomaly, we analyzed subsurface density structures along 13 northeastern-southwestern profiles and 35 northwestern-southeastern profiles with the interval of 2 km using the two dimensional Talwani's method (Talwani et al., 1959). In the analysis, we assumed a density structure with four layers: basement

  2. ETR, TRA642. BASEMENT SPACE ALLOCATION FOR EXPERIMENTERS CA. 1966, SOUTHEAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ETR, TRA-642. BASEMENT SPACE ALLOCATION FOR EXPERIMENTERS CA. 1966, SOUTHEAST QUADRANT OF FLOOR. WESTINGHOUSE ATOMIC POWER DIVISION (WAPD) AND BETTIS ATOMIC POWER LABORATORY (BAPL) CONSUME MOST OF THE QUADRANT. PHILLIPS PETROLEUM COMPANY ETR-E-2256, 12/1966. INL INDEX NO. 532-0642-00-706-021256, REV. F. - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  3. FET. Control and equipment building (TAN630). Basement floor plan. Tunnel ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FET. Control and equipment building (TAN-630). Basement floor plan. Tunnel to hangar (TAN-629). Electrical and chemical services. Ralph M. Parsons 1229-2 ANP/GE-630-A-1. Date: March 1957. Approved by INEEL Classification Office for public release. INEEL index code no. 036-0630-00-693-107080 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  4. MTR BUILDING INTERIOR, TRA603. BASEMENT. CAMERA IN WEST CORRIDOR FACING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    MTR BUILDING INTERIOR, TRA-603. BASEMENT. CAMERA IN WEST CORRIDOR FACING SOUTH. FREIGHT ELEVATOR IS AT RIGHT OF VIEW. AT CENTER VIEW IS MTR VAULT NO. 1, USED TO STORE SPECIAL OR FISSIONABLE MATERIALS. INL NEGATIVE NO. HD46-6-3. Mike Crane, Photographer, 2/2005 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  5. "We Dominate the Basement!": How Asian American Girls Construct a Borderland Community

    ERIC Educational Resources Information Center

    Tokunaga, Tomoko

    2016-01-01

    This article, based on two years of ethnographic fieldwork, explores the ways in which eight Asian American immigrant high school girls construct a borderland community, which they call the "Basement Group," after the place where they gather at school. While the girls struggle with displacement in the borderlands, including isolation in…

  6. Quantitative image analysis of laminin immunoreactivity in skin basement membrane irradiated with 1 GeV/nucleon iron particles

    NASA Technical Reports Server (NTRS)

    Costes, S.; Streuli, C. H.; Barcellos-Hoff, M. H.

    2000-01-01

    We previously reported that laminin immunoreactivity in mouse mammary epithelium is altered shortly after whole-body irradiation with 0.8 Gy from 600 MeV/nucleon iron ions but is unaffected after exposure to sparsely ionizing radiation. This observation led us to propose that the effect could be due to protein damage from the high ionization density of the ion tracks. If so, we predicted that it would be evident soon after radiation exposure in basement membranes of other tissues and would depend on ion fluence. To test this hypothesis, we used immunofluorescence, confocal laser scanning microscopy, and image segmentation techniques to quantify changes in the basement membrane of mouse skin epidermis. At 1 h after exposure to 1 GeV/nucleon iron ions with doses from 0.03 to 1.6 Gy, neither the visual appearance nor the mean pixel intensity of laminin in the basement membrane of mouse dorsal skin epidermis was altered compared to sham-irradiated tissue. This result does not support the hypothesis that particle traversal directly affects laminin protein integrity. However, the mean pixel intensity of laminin immunoreactivity was significantly decreased in epidermal basement membrane at 48 and 96 h after exposure to 0.8 Gy 1 GeV/nucleon iron ions. We confirmed this effect with two additional antibodies raised against affinity-purified laminin 1 and the E3 fragment of the long-arm of laminin 1. In contrast, collagen type IV, another component of the basement membrane, was unaffected. Our studies demonstrate quantitatively that densely ionizing radiation elicits changes in skin microenvironments distinct from those induced by sparsely ionizing radiation. Such effects may might contribute to the carcinogenic potential of densely ionizing radiation by altering cellular signaling cascades mediated by cell-extracellular matrix interactions.

  7. 42 CFR 84.1133 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Harnesses; installation and construction; minimum requirements. 84.1133 Section 84.1133 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE...

  8. 42 CFR 84.1133 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Harnesses; installation and construction; minimum requirements. 84.1133 Section 84.1133 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE...

  9. 42 CFR 84.1133 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Harnesses; installation and construction; minimum requirements. 84.1133 Section 84.1133 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE...

  10. 42 CFR 84.1133 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Harnesses; installation and construction; minimum requirements. 84.1133 Section 84.1133 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE...

  11. 42 CFR 84.1133 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Harnesses; installation and construction; minimum requirements. 84.1133 Section 84.1133 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE...

  12. 42 CFR 84.116 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Harnesses; installation and construction; minimum requirements. 84.116 Section 84.116 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE...

  13. 42 CFR 84.116 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Harnesses; installation and construction; minimum requirements. 84.116 Section 84.116 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE...

  14. 42 CFR 84.116 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Harnesses; installation and construction; minimum requirements. 84.116 Section 84.116 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE...

  15. 42 CFR 84.116 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Harnesses; installation and construction; minimum requirements. 84.116 Section 84.116 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE...

  16. 42 CFR 84.116 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Harnesses; installation and construction; minimum requirements. 84.116 Section 84.116 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE...

  17. High-Density Terminal Box for Testing Wire Harness

    NASA Technical Reports Server (NTRS)

    Pierce, W. B.; Collins, W. G.

    1982-01-01

    Compact terminal box provides access to complex wiring harnesses for testing. Box accommodates more than twice as many wires as previous boxes. Box takes in wires via cable connectors and distributes them to contacts on box face. Instead of separate insulated jacks in metal face panel, box uses pairs of small military-standard metal sockets in precision-drilled plastic panel. Shorting plug provides continuity for wires when not being tested.

  18. 2. Basement tunnel plan: Pine (Building 6, HABS DC349AA), Linden ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Basement tunnel plan: Pine (Building 6, HABS DC-349-AA), Linden (Building 28 HABS DC-349-AD), Holly (Building 29, HABS DC-349-AE), East Lodge / Detached Nurses Home (Building 30, HABS DC-349-AB) - St. Elizabeths Hospital, Tunnels, 2700 Martin Luther King Jr. Avenue, Southeast, Washington, District of Columbia, DC

  19. Observations of hydrotectonic stress/strain events at a basement high at the Nicoya outer rise

    NASA Astrophysics Data System (ADS)

    Tryon, M. D.; Brown, K. M.

    2005-12-01

    There is substantial and growing evidence from heat flow and coring investigations that the oceanic plate off Costa Rica is highly hydrologically active and that this activity is responsible for one of the most anomalously cold thermal environments encountered in the oceanic environment. Recent work by Fisher, et al. has identified limited regions above certain topographic highs with extremely high heat flows. Pore water profiles from cores above these thinly sedimented basement highs suggest upward flow on the order of ~1 cm/yr. These highs may be the principal regions of out-flow from the basement in this region and, thus, can potentially be used to constrain the general level of hydrologic activity. The nine Chemical and Aqueous Transport (CAT) meters we deployed at one of the highest heatflow sites provide a temporal record of both in-flow and out-flow of aqueous fluids at rates as low as 0.1 mm/yr. Our objective was to provide a direct measurement of long term flow rates to address the following questions: (1) What are the characteristic fluid fluxes at basement highs of the low heat flow region of the northern Costa Rican incoming plate, and (2) is this flow temporally variable? The results of the instrument deployments agree quite closely in general with the coring results in that the background rates are on the order of 1 cm/yr or less. There is, however, considerable detail in the temporal records which suggest small scale tectonic stress transients causing temporary increases in flow rate. While this is certainly not an area of major tectonic activity, the site is located at the top of the outer rise where one would expect bending-related stress and fault reactivation to occur. The CAT meters are capable of detecting minute strain events in the underlying sediments and therefore may be detecting small localized strain events. Two periods of increased flow lasting a few weeks each occur during the 5 month deployment and are indicated on all of the

  20. Polymetamorphic evolution of the granulite-facies Paleoproterozoic basement of the Kabul Block, Afghanistan

    NASA Astrophysics Data System (ADS)

    Collett, Stephen; Faryad, Shah Wali; Mosazai, Amir Mohammad

    2015-08-01

    The Kabul Block is an elongate crustal fragment which cuts across the Afghan Central Blocks, adjoining the Indian and Eurasian continents. Bounded by major strike slip faults and ophiolitic material thrust onto either side, the block contains a strongly metamorphosed basement consisting of some of the only quantifiably Proterozoic rocks south of the Herat-Panjshir Suture Zone. The basement rocks crop-out extensively in the vicinity of Kabul City and consist predominantly of migmatites, gneisses, schists and small amounts of higher-grade granulite-facies rocks. Granulite-facies assemblages were identified in felsic and mafic siliceous rocks as well as impure carbonates. Granulite-facies conditions are recorded by the presence of orthopyroxene overgrowing biotite in felsic rocks; by orthopyroxene overgrowing amphibole in mafic rocks and by the presence of olivine and clinohumite in the marbles. The granulite-facies assemblages are overprinted by a younger amphibolite-facies event that is characterized by the growth of garnet at the expense of the granulite-facies phases. Pressure-temperature (P-T) conditions for the granulite-facies event of around 850 °C and up to 7 kbar were calculated through conventional thermobarometry and phase equilibria modeling. The younger, amphibolite-facies event shows moderately higher pressures of up to 8.5 kbar at around 600 °C. This metamorphism likely corresponds to the dominant metamorphic event within the basement of the Kabul Block. The results of this work are combined with the litho-stratigraphic relations and recent geochronological dating to analyze envisaged Paleoproterozoic and Neoproterozoic metamorphic events in the Kabul Block.

  1. Gravitational salt tectonics above a rising basement plateau offshore Algeria

    NASA Astrophysics Data System (ADS)

    Gaullier, Virginie; Vendeville, Bruno C.; Besème, Grégoire; Legoux, Gaetan; Déverchère, Jacques; Lymer, Gaël

    2017-04-01

    Seismic data (survey "MARADJA 1", 2003) offshore the Algerian coast have imaged an unexpected deformation pattern of the Messinian salt (Mobile Unit; MU) and its sedimentary overburden (Messinian Upper Unit and Plio-Quaternary) above an actively rising plateau in the subsalt basement. From a geodynamic point of view, the region is undergoing crustal convergence, as attested by the Boumerdes earthquake (2003, magnitude 6.8). The rise of this plateau, forming a 3D promontory restricted to the area offshore Algiers, is associated with that geodynamic setting. The seismic profiles show several subsalt thrusts (Domzig et al. 2006). The data provided additional information on the deformation of the Messinian mobile evaporitic unit and its Plio-Quaternary overburden. Margin-perpendicular profiles show mostly compressional features (anticlines and synclines) that had little activity during Messinian times, then grew more during Plio-Quaternary times. A few normal faults are also present, but are not accompanied by salt rise. By contrast, margin-parallel profiles clearly show that extensional, reactive salt diapiric ridges (symptomatic with their triangular shape in cross section) formed early, as early as the time of deposition of the Messinian Upper Unit, as recorded by fan-shaped strata. These ridges have recorded E-W, thin-skinned gravity gliding above the Messinian salt, as a response to the rise of the basement plateau. We tested this hypothesis using two analogue models, one where we assumed that the rise of the plateau started after Messinian times (initially tabular salt across the entire region), the second model assumed that the plateau had already risen partially as the Messininan Mobile Unit was deposited (salt initially thinner above the plateau than in the adjacent regions). In both experiments, the rise of the plateau generated preferential E-W extension above the salt, combined with N-S shortening. Extension was caused by gravity gliding of the salt from

  2. 42 CFR 84.73 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Harnesses; installation and construction; minimum requirements. 84.73 Section 84.73 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self...

  3. 42 CFR 84.73 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Harnesses; installation and construction; minimum requirements. 84.73 Section 84.73 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self...

  4. 42 CFR 84.73 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Harnesses; installation and construction; minimum requirements. 84.73 Section 84.73 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self...

  5. 42 CFR 84.73 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Harnesses; installation and construction; minimum requirements. 84.73 Section 84.73 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self...

  6. 42 CFR 84.73 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Harnesses; installation and construction; minimum requirements. 84.73 Section 84.73 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self...

  7. Repair Air Conditioning, COC Bldg 2605, Basement Plan. By Strategic ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Repair Air Conditioning, COC Bldg 2605, Basement Plan. By Strategic Air Command, Civil Engineering. Drawing no. R-156, sheet no. 1 of 4, 15 August 1968; project no. MAR-125-8;CE-572; file drawer 2605-5. Last revised 31 August 1968?. Scale one-eighth inch and one-quarter inch to one foot. 29x41 inches. pencil on paper - March Air Force Base, Strategic Air Command, Combat Operations Center, 5220 Riverside Drive, Moreno Valley, Riverside County, CA

  8. Embryoid body attachment to reconstituted basement membrane induces a genetic program of epithelial differentiation via jun N-terminal kinase signaling.

    PubMed

    Ho, Hoang-Yen; Moffat, Ryan C; Patel, Rupal V; Awah, Franklin N; Baloue, Kaitrin; Crowe, David L

    2010-09-01

    Embryonic stem (ES) cells are derived from early stage mammalian embryos and have broad developmental potential. These cells can be manipulated experimentally to generate cells of multiple tissue types which could be important in treating human diseases. The ability to produce relevant amounts of these differentiated cell populations creates the basis for clinical interventions in tissue regeneration and repair. Understanding how embryonic stem cells differentiate also can reveal important insights into cell biology. A previously reported mouse embryonic stem cell model demonstrated that differentiated epithelial cells migrated out of embryoid bodies attached to reconstituted basement membrane. We used genomic technology to profile ES cell populations in order to understand the molecular mechanisms leading to epithelial differentiation. Cells with characteristics of cultured epithelium migrated from embryoid bodies attached to reconstituted basement membrane. However, cells that comprised embryoid bodies also rapidly lost ES cell-specific gene expression and expressed proteins characteristic of stratified epithelia within hours of attachment to basement membrane. Gene expression profiling of sorted cell populations revealed upregulation of the BMP/TGFbeta signaling pathway, which was not sufficient for epithelial differentiation in the absence of basement membrane attachment. Activation of c-jun N-terminal kinase 1 (JNK1) and increased expression of Jun family transcription factors was observed during epithelial differentiation of ES cells. Inhibition of JNK signaling completely blocked epithelial differentiation in this model, revealing a key mechanism by which ES cells adopt epithelial characteristics via basement membrane attachment. Copyright (c) 2010 Elsevier B.V. All rights reserved.

  9. Proteinases secreted by Fasciola hepatica degrade extracellular matrix and basement membrane components.

    PubMed

    Berasaín, P; Goñi, F; McGonigle, S; Dowd, A; Dalton, J P; Frangione, B; Carmona, C

    1997-02-01

    The invasive stages of the parasitic trematode Fasciola hepatica release proteinases into the medium in which they are maintained. In this study, we investigated the interaction of F. hepatica excretory/secretory (E/S) products and 2 cysteine proteinases (CL1 and CL2) purified from these products with extracellular matrix and basement membrane macromolecules. Fasciola hepatica E/S products contained collagenolytic activity on fibrillar types I and III collagen as well as basement membrane type IV collagen. CL1 and CL2 were capable of degrading acid-soluble type III and type IV collagen but not insoluble type I collagen. In contrast, neither the E/S products nor the purified CL1 and CL2 showed elastinolytic activity. Fibronectin and laminin were degraded by E/S products and by CL1 and CL2. Sequence analysis of fibronectin degradation products showed that the fragments obtained corresponded to complete biologically active domains. These results indicate that the cysteine proteinases secreted by F. hepatica may be involved in the process of tissue invasion by the parasite.

  10. Nature of the Yucatan Block Basement as Derived From Study of Granitic Clasts in the Impact Breccias of Chicxulub Crater

    NASA Astrophysics Data System (ADS)

    Vera-Sanchez, P.; Rebolledo-Vieyra, M.; Perez-Cruz, L.; Urrutia-Fucugauchi, J.

    2008-05-01

    The tectonic and petrologic nature of the basement of the Yucatan Block is studied from analyses of basement clasts present in the impact suevitic breccias of Chicxulub crater. The impact breccias have been sampled as part of the drilling projects conducted in the Yucatan peninsula by Petroleos Mexicanos, the National University of Mexico and the Chicxulub Scientific Drilling Project. Samples analyzed come mainly from the Yaxcopoil-1, Tekax, and Santa Elena boreholes, and partly from Pemex boreholes. In this study we concentrate on clasts of the granites, granodiorites and quartzmonzonites in the impact breccias. We report major and trace element geochemical and petrological data, which are compared with data from the granitic and volcanic rocks from the Maya Mountains in Belize and from the Swannee terrane in Florida. Basement granitic clasts analyzed present intermediate to acidic sub-alkaline compositions. Plots of major oxides (e.g., Al2O3, Fe2O3, TiO2 and CaO) and trace elements (e.g., Th, Y, Hf, Nb and Zr) versus silica allow separation of samples into two major groups, which can be compared to units in the Maya Mountains and in Florida basement. The impact suevitic breccia samples have been affected by alteration likely related to the hydrothermal processes associated with the crater melt sheet. Cloritization, seritization and fenitization alterations are recognized, due to the long term hydrothermalism. Krogh et al. (1993) reported U-Pb dates on zircons from the suevitic breccias, which gave dates of 545 +/- 5 Ma and 418 +/- 6 Ma, which were interpreted in terms of the deep granitic metamorphic Yucatan basement. The younger date correlates with the age for the Osceola Granite and the St. Lucie metamorphic complex of the Swannee terrane in the Florida peninsula. The intrusive rocks in the Yucatan basement may be related to approx. 418 Ma ago collisional event in the Late Silurian.

  11. Fluid and chemical fluxes along a buried-basement ridge in the eastern Juan de Fuca Ridge flank

    NASA Astrophysics Data System (ADS)

    Hulme, S.; Wheat, C. G.

    2010-12-01

    Hydrothermal fluid circulation within oceanic crust at low temperatures affects global biogeochemical cycles, with the volume of fluid circulation rivaling that of the world’s water flux to the oceans from rivers. Our work focuses on the best studied low temperature hydrothermal system on the eastern flank of the Juan de Fuca Ridge where a buried basement ridge 100 km from the active spreading axis has been sampled with a variety of mediums. We use data from deep sea drilling, gravity coring, and submersible operations from five sites along-strike of the buried ridge to better constrain the chemical and fluid fluxes along this transect. A transport (advection-diffusion) model is applied to the data, constraining the volumetric fluid flux per unit length within the oceanic crust from 0.05 and 0.2 m3 y-1 cm-1 and identifying conservative elements within this system. Using an average fluid flux, reactive fluxes are determined for non-conservative elements within basaltic crust for twenty-four chemical species. Conservative species include K, Cl, SO4, Ba, Sr, Cs, Mo, and Y. Only Ca and the rare earth elements Ce and Gd are produced by basaltic basement. The remaining chemical species Mg, Na, ammonium, Li, Rb, Mn, Fe, Co, Zn, Cd, U, La and Yb are all consumed within upper basaltic basement. Fluxes of potentially-bioavailable redox species ammonium, Fe, and Mn into the upper basaltic basement are 3 to 20 nmol y-1cm-2. Possible mechanisms of removal are suggested, placing constraints on microbial metabolic activity and biomineralization.

  12. Failed Pavlik harness treatment for DDH as a risk factor for avascular necrosis.

    PubMed

    Tiruveedhula, Madhu; Reading, Isabel C; Clarke, Nicholas M P

    2015-03-01

    Avascular necrosis (AVN) of the femoral head is an irreversible complication seen in the treatment of developmental dysplasia of hip (DDH) with the Pavlik harness. Its incidence is reported to be low after successful reduction of the hip but high if the hip is not concentrically relocated. We aim to investigate its incidence after failed Pavlik harness treatment. We prospectively followed up a group of children who failed Pavlik harness treatment for DDH treated at our institution by the senior author between 1988 and 2001 and compared their rates of AVN with a group of children who presented late and hence were treated surgically. AVN was graded as described by Kalamchi and MacEwen and only grade 2 to 4 AVN was considered significant and included in the analysis. Thirty-seven hips were included in the failed Pavlik group (group 1) and 86 hips in the no Pavlik group (group 2). Ten hips in group 1 developed AVN (27%), whereas only 7 hips in group 2 (8%) developed AVN; the odds of developing AVN after failed Pavlik treatment was 4.7 (95% confidence interval, 1.3-14.1) (P=0.009) with a relative risk of 3.32 (range, 1.37 to 8.05). There was no statistically significant association observed with duration of splintage and severity of AVN (Spearman's correlation, -0.46; P=0.18). However, there was a positive correlation noted with age at presentation and severity of AVN. Therefore, we advise close monitoring of hips in the Pavlik harness and discontinue its use if the hips are not reduced within 3 weeks. Level III.

  13. Manufacture and quality control of interconnecting wire harnesses, Volume 3

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The document covers interconnecting wire harnesses defined in the design standard, including type 6, enclosed in TFE heat shrink tubing; and type 7, flexible armored. Knowledge gained through experience on the Saturn 5 program coupled with recent advances in techniques, materials, and processes was incorporated into this document.

  14. Harnessing Linguistic Variation to Improve Education. Rethinking Education. Volume 5

    ERIC Educational Resources Information Center

    Yiakoumetti, Androula, Ed.

    2012-01-01

    This volume brings together research carried out in a variety of geographic and linguistic contexts including Africa, Asia, Australia, Canada, the Caribbean, Europe and the United States and explores efforts to incorporate linguistic diversity into education and to "harness" this diversity for learners' benefit. It challenges the largely…

  15. A 'Propagating' Active Across-Arc Normal Fault Shows Rupture Process of the Basement: the Case of the Southwestern Ryukyu Arc

    NASA Astrophysics Data System (ADS)

    Matsumoto, T.; Shinjo, R.; Nakamura, M.; Kubo, A.; Doi, A.; Tamanaha, S.

    2011-12-01

    Ryukyu Arc is located on the southwestern extension of Japanese Island-arc towards the east of Taiwan Island along the margin of the Asian continent off China. The island-arc forms an arcuate trench-arc-backarc system. A NW-ward subduction of the Philippine Sea Plate (PSP)at a rate of 6-8 cm/y relative to the Eurasian Plate (EP) causes frequent earthquakes. The PSP is subducting almost normally in the north-central area and more obliquely around the southwestern area. Behind the arc-trench system, the Okinawa Trough (OT) was formed by back-arc rifting, where active hydrothermal vent systems have been discovered. Several across-arc submarine faults are located in the central and southern Ryukyu Arc. The East Ishigaki Fault (EIF) is one of the across-arc normal faults located in the southwestern Ryukyu Arc, ranging by 44km and extending from SE to NW. This fault was surveyed by SEABAT8160 multibeam echo sounder and by ROV Hyper-Dolphin in 2005 and 2008. The result shows that the main fault consists of five fault segments. A branched segment from the main fault was also observed. The southernmost segment is most mature (oldest but still active) and the northernmost one is most nascent. This suggests the north-westward propagation of the fault rupture corresponding to the rifting of the southwestern OT and the southward retreat of the arc-trench system. Considering that the fault is segmented and in some part branched, propagation might take place episodically rather than continuously from SE to NW. The ROV survey also revealed the rupture process of the limestone basement along this fault from the nascent stage to the mature stage. Most of the rock samples collected from the basement outcrop were limestone blocks (or calcareous sedimentary rocks). Limestone basement was observed to the west on the hanging wall far away from the main fault scarp. Then fine-grained sand with ripple marks was observed towards the main scarp. Limestone basement was observed on the main

  16. Theoretical Study of Decomposition Pathways for HArF and HKrF

    NASA Technical Reports Server (NTRS)

    Chaban, Galina M.; Lundell, Jan; Gerber, R. Benny; Kwak, Donchan (Technical Monitor)

    2002-01-01

    To provide theoretical insights into the stability and dynamics of the new rare gas compounds HArF and HKrF, reaction paths for decomposition processes HRgF to Rg + HF and HRgF to H + Rg + F (Rg = Ar, Kr) are calculated using ab initio electronic structure methods. The bending channels, HRgF to Rg + HF, are described by single-configurational MP2 and CCSD(T) electronic structure methods, while the linear decomposition paths, HRgF to H + Rg + F, require the use of multi-configurational wave functions that include dynamic correlation and are size extensive. HArF and HKrF molecules are found to be energetically stable with respect to atomic dissociation products (H + Rg + F) and separated by substantial energy barriers from Rg + HF products, which ensure their kinetic stability. The results are compatible with experimental data on these systems.

  17. Depth-to-basement, sediment-thickness, and bathymetry data for the deep-sea basins offshore of Washington, Oregon, and California

    USGS Publications Warehouse

    Wong, Florence L.; Grim, Muriel S.

    2015-01-01

    Contours and derivative raster files of depth-to-basement, sediment-thickness, and bathymetry data for the area offshore of Washington, Oregon, and California are provided here as GIS-ready shapefiles and GeoTIFF files. The data were used to generate paper maps in 1992 and 1993 from 1984 surveys of the U.S. Exclusive Economic Zone by the U.S. Geological Survey for depth to basement and sediment thickness, and from older data for the bathymetry.

  18. ETR BUILDING, TRA642, INTERIOR. BASEMENT. CAMERA FACES SOUTH AND LOOKS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ETR BUILDING, TRA-642, INTERIOR. BASEMENT. CAMERA FACES SOUTH AND LOOKS AT DOOR TO M-3 CUBICLE. CUBICLE WALLS ARE MADE OF LEAD SHIELDING BRICKS. VALVE HANDLES AND STEMS PERTAIN TO SAMPLING. METAL SHIELDING DOOR. NOTE GLOVE BOX TO RIGHT OF CUBICLE DOOR. INL NEGATIVE NO. HD-46-21-3. Mike Crane, Photographer, 2/2005 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  19. Basement structures over Rio Grande Rise from gravity inversion

    NASA Astrophysics Data System (ADS)

    Constantino, Renata Regina; Hackspacher, Peter Christian; de Souza, Iata Anderson; Lima Costa, Iago Sousa

    2017-04-01

    The basement depth in the Rio Grande Rise (RGR), South Atlantic, is estimated from combining gravity data obtained from satellite altimetry, marine surveys, bathymetry, sediment thickness and crustal thickness information. We formulate a crustal model of the region by inverse gravity modeling. The effect of the sediment layer is evaluated using the global sediment thickness model of National Oceanic and Atmospheric Administration (NOAA) and fitting the sediment compaction model to observed density values from Deep Sea Drilling Project (DSDP) reports. The Global Relief Model ETOPO1 and constraining data from seismic interpretation on crustal thickness are integrated in the inversion process. The modeled Moho depth values vary between 6 and 27 km over the area, being thicker under the RGR and also in the direction of São Paulo Plateau. The inversion for the gravity-equivalent basement topography is applied to gravity residual data, which is free from the gravity effect of sediments and from the gravity effect of the estimated Moho interface. We find several short-wavelengths structures not present in the bathymetry data. Our model shows a rift crossing the entire Rio Grande Rise deeper than previously presented in literature, with depths up to 5 km in the East Rio Grande Rise (ERGR) and deeper in the West Rio Grande Rise (WRGR), reaching 6.4 km. An interesting NS structure that goes from 34°S and extends through de São Paulo Ridge may be related to the South Atlantic Opening and could reveal an extinct spreading center.

  20. Role of 17 beta-estradiol on type IV collagen fibers volumetric density in the basement membrane of bladder wall.

    PubMed

    de Fraga, Rogerio; Dambros, Miriam; Miyaoka, Ricardo; Riccetto, Cássio Luís Zanettini; Palma, Paulo César Rodrigues

    2007-10-01

    The authors quantified the type IV collagen fibers volumetric density in the basement membrane of bladder wall of ovariectomized rats with and without estradiol replacement. This study was conducted on 40 Wistar rats (3 months old) randomly divided in 4 groups: group 1, remained intact (control); group 2, submitted to bilateral oophorectomy and daily replacement 4 weeks later of 17 beta-estradiol for 12 weeks; group 3, sham operated and daily replacement 4 weeks later of sesame oil for 12 weeks; and group 4, submitted to bilateral oophorectomy and killed after 12 weeks. It was used in immunohistochemistry evaluation using type IV collagen polyclonal antibody to stain the fibers on paraffin rat bladder sections. The M-42 stereological grid system was used to analyze the fibers. Ovariectomy had an increase effect on the volumetric density of the type IV collagen fibers in the basement membrane of rat bladder wall. Estradiol replacement in castrated animals demonstrated a significative difference in the stereological parameters when compared to the castrated group without hormonal replacement. Surgical castration performed on rats induced an increasing volumetric density of type IV collagen fibers in the basement membrane of rats bladder wall and the estradiol treatment had a significant effect in keeping a low volumetric density of type IV collagen fibers in the basement membrane of rats bladder wall.

  1. Contour mapping of relic structures in the Precambrian basement of the Reelfoot rift, North American midcontinent

    USGS Publications Warehouse

    Dart, R.L.; Swolfs, H.S.

    1998-01-01

    A new contour map of the basement of the Reelfoot rift constructed from drill hole and seismic reflection data shows the general surface configuration as well as several major and minor structural features. The major features are two asymmetric intrarift basins, bounded by three structural highs, and the rift margins. The basins are oriented normal to the northeast trend of the rift. Two of the highs appear to be ridges of undetermined width that extend across the rift. The third high is an isolated dome or platform located between the basins. The minor features are three linear structures of low relief oriented subparallel to the trend of the rift. Two of these, located within the rift basins, may divide the rift basins into paired subbasins. These mapped features may be the remnants of initial extensional rifting, half graben faulting, and basement subsidence. The rift basins are interpreted as having formed as opposing half graben, and the structural highs are interpreted as having formed as associated accommodation zones. Some of these features appear to be reactivated seismogenic structures within the modem midcontinent compressional stress regime. A detailed knowledge of the geometries of the Reelfoot rift's basement features, therefore, is essential when evaluating their seismic risk potential.

  2. Using Discussion Methods to Inspire Diversity: Harnessing Social & Cultural Capital

    ERIC Educational Resources Information Center

    Raison, Brian; Gordon, Beverly

    2012-01-01

    How can you better harness the powerful social capital that exists within diverse individuals, families, businesses, and schools to make positive impacts in your community? What could you add to your next meeting--a Chamber strategic planning session, an employee wellness program, a non-profit board development--to better connect participants with…

  3. Fuzzy logic modeling of the resistivity parameter and topography features for aquifer assessment in hydrogeological investigation of a crystalline basement complex

    NASA Astrophysics Data System (ADS)

    Adabanija, M. A.; Omidiora, E. O.; Olayinka, A. I.

    2008-05-01

    A linguistic fuzzy logic system (LFLS)-based expert system model has been developed for the assessment of aquifers for the location of productive water boreholes in a crystalline basement complex. The model design employed a multiple input/single output (MISO) approach with geoelectrical parameters and topographic features as input variables and control crisp value as the output. The application of the method to the data acquired in Khondalitic terrain, a basement complex in Vizianagaram District, south India, shows that potential groundwater resource zones that have control output values in the range 0.3295-0.3484 have a yield greater than 6,000 liters per hour (LPH). The range 0.3174-0.3226 gives a yield less than 4,000 LPH. The validation of the control crisp value using data acquired from Oban Massif, a basement complex in southeastern Nigeria, indicates a yield less than 3,000 LPH for control output values in the range 0.2938-0.3065. This validation corroborates the ability of control output values to predict a yield, thereby vindicating the applicability of linguistic fuzzy logic system in siting productive water boreholes in a basement complex.

  4. Structural analysis of a fractured basement reservoir, central Yemen

    NASA Astrophysics Data System (ADS)

    Veeningen, Resi; Rice, Hugh; Schneider, Dave; Grasemann, Bernhard; Decker, Kurt

    2013-04-01

    The Pan-African Arabian-Nubian Shield (ANS), within which Yemen lies, formed as a result of Neoproterozoic collisional events between c. 870-550 Ma. Several subsequent phases of extension occurred, from the Mesozoic (due to the breakup of Gondwana) to the Recent (forming the Gulf of Aden and the Red Sea). These resulted in the formation of numerous horst- and-graben structures and the development of fractured basement reservoirs in the southeast part of the ANS. Two drill cores from the Mesozoic Marib-Shabwa Basin, central Yemen, penetrated the upper part of the Pan-African basement. The cores show both a lithological and structural inhomogeneity, with variations in extension-related deformation structures such as dilatational breccias, open fractures and closed veins. At least three deformation events have been recognized: D1) Ductile to brittle NW-SE directed faulting during cooling of a granitic pluton. U-Pb zircon ages revealed an upper age limit for granite emplacement at 627±3.5 Ma. As these structures show evidence for ductile deformation, this event must have occurred during the Ediacaran, shortly after intrusion, since Rb/Sr and (U-Th)/He analyses show that subsequent re-heating of the basement did not take place. D2) The development of shallow dipping, NNE-SSW striking extensional faults that formed during the Upper Jurassic, simultaneously with the formation of the Marib-Shabwa Basin. These fractures are regularly cross-cut by D3. D3) Steeply dipping NNE-SSW to ENE-WSW veins that are consistent with the orientation of the opening of the Gulf of Aden. These faults are the youngest structures recognized. The formation of ductile to brittle faults in the granite (D1) resulted in a hydrothermally altered zone ca. 30 cm wide replacing (mainly) plagioclase with predominantly chlorite, as well as kaolinite and heavy element minerals such as pyrite. The alteration- induced porosity has an average value of 20%, indicating that the altered zone is potentially a

  5. Hello World: Harnessing social media for the Rosetta mission

    NASA Astrophysics Data System (ADS)

    Baldwin, E.; Mignone, C.; O'Flaherty, K. S.; Homfeld, A.-M.; Bauer, M.; McCaughrean, M. J.

    2015-10-01

    The European Space Agency's (ESA) comet-chasing Rosetta mission was launched in 2004, before social media became a popular tool for mainstream communication. By harnessing a range of platforms for communicating the key messages of this unprecedented space adventure as the spacecraft reached its destination ten years later, a wide range of new audiences were reached and could follow this once-in-a-lifetime mission.

  6. Two-dimensional basement modeling of central loop transient electromagnetic data from the central Azraq basin area, Jordan

    NASA Astrophysics Data System (ADS)

    Yogeshwar, P.; Tezkan, B.

    2017-01-01

    Thick sedimentary sequences are deposited in the central area of the Azraq basin in Jordan consisting mostly of hyper-saline clay and various evaporates. These sediment successions form the 10 km × 10 km large Azraq mudflat and are promising archives for a palaeoclimatical reconstruction. Besides palaeoclimatical research, the Azraq area is of tremendous importance to Jordan due to groundwater and mineral resources. The heavy exploitation of groundwater has lead to a drastic decline of the water table and drying out of the former Azraq Oasis. Two 7 and 5 km long transects were investigated from the periphery of the mudflat across its center using a total of 150 central loop transient electromagnetic (TEM) soundings. The scope of the survey was to detect the thickness of sedimentary deposits along both transects and to provide a basis for future drilling activities. We derive a two-dimensional model which can explain the TEM data for all soundings along each profile simultaneously. Previously uncertain depths of geological boundaries were determined along both transects. Particularly the thickness of the deposited mudflat sediments was identified and ranges from 40 m towards the periphery down to approximately 130 m at the deepest location. Besides that, the depth and lateral extent of a buried basalt layer was identified. In the basin center the groundwater is hyper-saline. The lateral extent of the saline water body was determined precisely along both transects. In order to investigate the detectability of the basement below the high conductive mudflat sediments an elaborate two-dimensional modeling study was performed. Both, the resistivity and depth of the basement were varied systematically. The basement resistivity cannot be determined precisely in most zones and may range roughly between 1 and 100 Ωm without deteriorating the misfit. In contrast to that, the depth down to the basement is detected accurately in most zones and along both transects. Varying

  7. SOME RESULTS FROM THE DEMONSTRATION OF INDOOR RADON REDUCTION MEASURES IN BLOCK BASEMENT HOUSES

    EPA Science Inventory

    Active soil ventilation techniques have been tested in 26 block-wall basement houses in eastern Pennsylvania with significantly elevated indoor radon concentrations, generally above 740 Bq/m3, and the results indicate that radon levels can be reduced substantially often below the...

  8. How can developing countries harness biotechnology to improve health?

    PubMed Central

    Daar, Abdallah S; Berndtson, Kathryn; Persad, Deepa L; Singer, Peter A

    2007-01-01

    Background The benefits of genomics and biotechnology are concentrated primarily in the industrialized world, while their potential to combat neglected diseases in the developing world has been largely untapped. Without building developing world biotechnology capacity to address local health needs, this disparity will only intensify. To assess the potential of genomics to address health needs in the developing world, the McLaughlin-Rotman Centre for Global Health, along with local partners, organized five courses on Genomics and Public Health Policy in the developing world. The overall objective of the courses was to collectively explore how to best harness genomics to improve health in each region. This article presents and analyzes the recommendations from all five courses. Discussion In this paper we analyze recommendations from 232 developing world experts from 58 countries who sought to answer how best to harness biotechnology to improve health in their regions. We divide their recommendations into four categories: science; finance; ethics, society and culture; and politics. Summary The Courses' recommendations can be summarized across the four categories listed above: Science - Collaborate through national, regional, and international networks - Survey and build capacity based on proven models through education, training, and needs assessments Finance - Develop regulatory and intellectual property frameworks for commercialization of biotechnology - Enhance funding and affordability of biotechnology - Improve the academic-industry interface and the role of small and medium enterprise Ethics, Society, Culture - Develop public engagement strategies to inform and educate the public about developments in genomics and biotechnology - Develop capacity to address ethical, social and cultural issues - Improve accessibility and equity Politics - Strengthen understanding, leadership and support at the political level for biotechnology - Develop policies outlining

  9. How can developing countries harness biotechnology to improve health?

    PubMed

    Daar, Abdallah S; Berndtson, Kathryn; Persad, Deepa L; Singer, Peter A

    2007-12-03

    The benefits of genomics and biotechnology are concentrated primarily in the industrialized world, while their potential to combat neglected diseases in the developing world has been largely untapped. Without building developing world biotechnology capacity to address local health needs, this disparity will only intensify. To assess the potential of genomics to address health needs in the developing world, the McLaughlin-Rotman Centre for Global Health, along with local partners, organized five courses on Genomics and Public Health Policy in the developing world. The overall objective of the courses was to collectively explore how to best harness genomics to improve health in each region. This article presents and analyzes the recommendations from all five courses. In this paper we analyze recommendations from 232 developing world experts from 58 countries who sought to answer how best to harness biotechnology to improve health in their regions. We divide their recommendations into four categories: science; finance; ethics, society and culture; and politics. The Courses' recommendations can be summarized across the four categories listed above: SCIENCE: - Collaborate through national, regional, and international networks- Survey and build capacity based on proven models through education, training, and needs assessments FINANCE: - Develop regulatory and intellectual property frameworks for commercialization of biotechnology- Enhance funding and affordability of biotechnology- Improve the academic-industry interface and the role of small and medium enterprise ETHICS, SOCIETY, CULTURE: - Develop public engagement strategies to inform and educate the public about developments in genomics and biotechnology- Develop capacity to address ethical, social and cultural issues- Improve accessibility and equity POLITICS: - Strengthen understanding, leadership and support at the political level for biotechnology- Develop policies outlining national biotechnology strategy

  10. Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors.

    PubMed

    Benedicto, Ignacio; Lehmann, Guillermo L; Ginsberg, Michael; Nolan, Daniel J; Bareja, Rohan; Elemento, Olivier; Salfati, Zelda; Alam, Nazia M; Prusky, Glen T; Llanos, Pierre; Rabbany, Sina Y; Maminishkis, Arvydas; Miller, Sheldon S; Rafii, Shahin; Rodriguez-Boulan, Enrique

    2017-05-19

    The outer blood-retina barrier is established through the coordinated terminal maturation of the retinal pigment epithelium (RPE), fenestrated choroid endothelial cells (ECs) and Bruch's membrane, a highly organized basement membrane that lies between both cell types. Here we study the contribution of choroid ECs to this process by comparing their gene expression profile before (P5) and after (P30) the critical postnatal period when mice acquire mature visual function. Transcriptome analyses show that expression of extracellular matrix-related genes changes dramatically over this period. Co-culture experiments support the existence of a novel regulatory pathway: ECs secrete factors that remodel RPE basement membrane, and integrin receptors sense these changes triggering Rho GTPase signals that modulate RPE tight junctions and enhance RPE barrier function. We anticipate our results will spawn a search for additional roles of choroid ECs in RPE physiology and disease.

  11. Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors

    PubMed Central

    Benedicto, Ignacio; Lehmann, Guillermo L.; Ginsberg, Michael; Nolan, Daniel J.; Bareja, Rohan; Elemento, Olivier; Salfati, Zelda; Alam, Nazia M.; Prusky, Glen T.; Llanos, Pierre; Rabbany, Sina Y.; Maminishkis, Arvydas; Miller, Sheldon S.; Rafii, Shahin; Rodriguez-Boulan, Enrique

    2017-01-01

    The outer blood-retina barrier is established through the coordinated terminal maturation of the retinal pigment epithelium (RPE), fenestrated choroid endothelial cells (ECs) and Bruch's membrane, a highly organized basement membrane that lies between both cell types. Here we study the contribution of choroid ECs to this process by comparing their gene expression profile before (P5) and after (P30) the critical postnatal period when mice acquire mature visual function. Transcriptome analyses show that expression of extracellular matrix-related genes changes dramatically over this period. Co-culture experiments support the existence of a novel regulatory pathway: ECs secrete factors that remodel RPE basement membrane, and integrin receptors sense these changes triggering Rho GTPase signals that modulate RPE tight junctions and enhance RPE barrier function. We anticipate our results will spawn a search for additional roles of choroid ECs in RPE physiology and disease. PMID:28524846

  12. PBF Reactor Building (PER620). Camera facing southeast in second basement. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PBF Reactor Building (PER-620). Camera facing southeast in second basement. Round form and reinforcing steel surround reactor vessel pit, which will be heavily shielded by several feet of concrete. Block-out is for door to sub-pile room. Rectangular form and rebar beyond pit is for canal wall. Photographer: John Capek. Date: March 10, 1967. INEEL negative no. 67-1643 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

  13. Uplift, Emergence, and Subsidence of the Gorda Escarpment Basement Ridge Offshore Cape Mendocino, CA

    NASA Astrophysics Data System (ADS)

    Hoover, Susan M.; Tréhu, Anne M.

    2017-12-01

    The Gorda Escarpment is a topographic step that characterizes the south side of the Mendocino Transform Fault east of 126oW and forms the northern edge of the Vizcaino Block. Seismic reflection data suggest that the basement beneath the northern edge of the Vizcaino is composed of east-west trending slivers of oceanic crust that form a 15 km wide band of buried ridges we call the Gorda Escarpment Basement Ridge (GEBR) to distinguish it from the northwest-trending basement structure that characterizes most of the Vizcaino Block. The history of uplift and subsidence of the GEBR is reconstructed by combining the seismic reflection profiles with age and lithological constraints from ODP Site 1022, gravity cores, and grab samples from the northern face of the Escarpment recovered using a remotely operated vehicle. Uplift of the GEBR began prior to 6 Ma, and it was above sea level 3.7-2.5 Ma. GEBR uplift and emergence coincided with sediment deposition on the southern flank of the GEBR that we interpret as indicative of strong upwelling and turbulence in the lee of a shallow ridge and island chain. A bright reflection, interpreted to be a sill, is observed south of the shallowest part of the GEBR. We speculate that this sill may reflect a larger, hidden intrusion at depth and that thermal expansion of the crust combined with tectonic forces to drive enhanced uplift of this segment of the plate boundary. The GEBR has been subsiding since 2.7 Ma, and its shallowest point is now 1,400 m below sea level.

  14. Microbial diversity within basement fluids of the sediment-buried Juan de Fuca Ridge flank

    PubMed Central

    Jungbluth, Sean P; Grote, Jana; Lin, Huei-Ting; Cowen, James P; Rappé, Michael S

    2013-01-01

    Despite its immense size, logistical and methodological constraints have largely limited microbiological investigations of the subseafloor basement biosphere. In this study, a unique sampling system was used to collect fluids from the subseafloor basaltic crust via a Circulation Obviation Retrofit Kit (CORK) observatory at Integrated Ocean Drilling Program borehole 1301A, located at a depth of 2667 m in the Pacific Ocean on the eastern flank of the Juan de Fuca Ridge. Here, a fluid delivery line directly accesses a 3.5 million years old basalt-hosted basement aquifer, overlaid by 262 m of sediment, which serves as a barrier to direct exchange with bottom seawater. At an average of 1.2 × 104 cells ml−1, microorganisms in borehole fluids were nearly an order of magnitude less abundant than in surrounding bottom seawater. Ribosomal RNA genes were characterized from basement fluids, providing the first snapshots of microbial community structure using a high-integrity fluid delivery line. Interestingly, microbial communities retrieved from different CORKs (1026B and 1301A) nearly a decade apart shared major community members, consistent with hydrogeological connectivity. However, over three sampling years, the dominant gene clone lineage changed from relatives of Candidatus Desulforudis audaxviator within the bacterial phylum Firmicutes in 2008 to the Miscellaneous Crenarchaeotic Group in 2009 and a lineage within the JTB35 group of Gammaproteobacteria in 2010, and statistically significant variation in microbial community structure was observed. The enumeration of different phylogenetic groups of cells within borehole 1301A fluids supported our observation that the deep subsurface microbial community was temporally dynamic. PMID:22791235

  15. Ages of pre-rift basement and synrift rocks along the conjugate rift and transform margins of the Argintine Precordillera and Laurentia

    USGS Publications Warehouse

    Thomas, William A.; Tucker, Robert D.; Astini, Ricardo A.; Denison, Rodger E.

    2012-01-01

    New geochronologic data from basement rocks support the interpretation that the Argentine Precordillera (Cuyania) terrane was rifted from the Ouachita embayment of the Iapetan margin of Laurentia. New data from the Ozark dome show a range of ages in two groups at 1466 ± 3 to 1462 ± 1 Ma and 1323 ± 2 to 1317 ± 2 Ma, consistent with existing data for the Eastern Granite-Rhyolite province and Southern Granite-Rhyolite province, respectively. Similarly, a newly determined age of 1364 ± 2 Ma for the Tishomingo Granite in the Arbuckle Mountains confirms previously published analyses for this part of the Southern Granite-Rhyolite province. Along with previously reported ages from basement olistoliths in Ordovician slope deposits in the Ouachita embayment, the data for basement ages support the interpretation that rocks of the Southern Granite-Rhyolite province form the margin of Laurentian crust around the corner of the Ouachita embayment, which is bounded by the Ouachita rift and Alabama-Oklahoma transform fault. In contrast, both west and east of the corner of the Ouachita embayment, Grenville-Llano basement (approximately 1325–1000 Ma) forms the rifted margin of Laurentia. New U/Pb zircon data from basement rocks in the southern part of the Argentine Precordillera indicate crystallization ages of 1205 ± 1 Ma and 1204 ± 2 Ma, consistent with previously reported ages (approximately 1250–1000 Ma) of basement rocks from other parts of the Precordillera. These data document multiple events within the same time span as multiple events in the Grenville orogeny in eastern Laurentia, and are consistent with Grenville-age rocks along the conjugate margins of the Precordillera and Laurentia. Ages from one newly analyzed collection, however, are older than those from other basement rocks in the Precordillera. These ages, from granodioritic-granitic basement clasts in a conglomerate olistolith in Ordovician slope deposits, are 1370 ± 2 Ma and 1367 ± 5 Ma. These older

  16. Two-stage formation model of the Junggar basin basement: Constraints to the growth style of Central Asian Orogenic Belt

    NASA Astrophysics Data System (ADS)

    He, Dengfa

    2016-04-01

    Junggar Basin is located in the central part of the Central Asian Orogenic Belt (CAOB). Its basement nature is a highly controversial scientific topic, involving the basic style and processes of crustal growth. Some researchers considered the basement of the Junggar Basin as a Precambrian continental crust, which is not consistent with the petrological compositions of the adjacent orogenic belts and the crust isotopic compositions revealed by the volcanic rocks in the basin. Others, on the contrary, proposed an oceanic crust basement model that does not match with the crustal thickness and geophysical characteristics of the Junggar area. Additionally, there are several viewponits, such as the duplex basement with the underlying Precambrian crystalline rocks and the overlying pre-Carboniferous folded basement, and the collaged basement by the Precambrian micro-continent block in the central part and the Hercynian accretionary folded belts circling it. Anyway, it is necessary to explain the property of basement rock, its strong inhomogeneous compositions as well as the geophysical features. In this paper, based on the borehole data from more than 300 industry wells drilled into the Carboniferous System, together with the high-resolution gravity and magnetic data (in a scale of 1:50,000), we made a detailed analysis of the basement structure, formation timing and processes and its later evolution on a basis of core geochemical and isotopic analysis. Firstly, we defined the Mahu Pre-Cambrian micro-continental block in the juvenile crust of Junggar Basin according to the Hf isotopic analysis of the Carboniferous volcanic rocks. Secondly, the results of the tectonic setting and basin analysis suggest that the Junggar area incorporates three approximately E-W trending island arc belts (from north to south: Yemaquan- Wulungu-Chingiz, Jiangjunmiao-Luliang-Darbut and Zhongguai-Mosuowan- Baijiahai-Qitai island arcs respectively) and intervened three approximately E-W trending

  17. A Novel Function for the nm23-Hl Gene: Overexpression in Human Breast Carcinoma Cells Leads to the Formation of Basement Membrane and Growth Arrest

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Howlett, Anthony R; Petersen, Ole W; Steeg, Patricia S

    1994-01-01

    We have developed a culture system using reconstituted basement membrane components in which normal human mammary epithelial cells exhibit several aspects of the development and differentiation process, including formation of acinar-like structures, production and basal deposition of basement membrane components, and production and apical secretion of sialomucins. Cell lines and cultures from human breast carcinomas failed to recapitulate this process. The data indicate the importance of cellular interactions with the basement membrane in the regulation of normal breast differentiation and, potentially, its loss in neoplasia. Our purpose was to use this assay to investigate the role of the putative metastasismore » suppressor gene nm23-H1 in mammary development and differentiation. The metastatic human breast carcinoma cell line MDA-MB-435, clones transfected with a control pCMVBamneo vector, and clones transfected with pCMVBamneo vector containing nm23-H1 complementary DNA (the latter of which exhibited a substantial reduction in spontaneous metastatic potential in vivo) were cultured within a reconstituted basement membrane. Clones were examined for formation of acinus-like spheres, deposition of basement membrane components, production of sialomucin, polarization, and growth arrest. In contrast to the parental cell line and control transfectants, MDA-MB-435 breast carcinoma cells overexpressing Nm23-H1 protein regained several aspects of the normal phenotype within reconstituted basement membrane. Nm23-H1 protein-positive cells formed organized acinus-like spheres, deposited the basement membrane components type IV collagen and, to some extent, laminin to the outside of the spheres, expressed sialomucin, and growth arrested. Growth arrest of Nm23-H1 protein-positive cells was preceded by and correlated with formation of a basement membrane, suggesting a causal relationship. The data indicate a previously unidentified cause-and-effect relationship between nm23

  18. PBF Reactor Building (PER620) basement, inside cubicle 13. Lead bricks ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PBF Reactor Building (PER-620) basement, inside cubicle 13. Lead bricks shield the fission product detection system (FPDS). The system detected fission products in pressure loop from in-pile tube. shielding was to prevent other radiation in cubicle from interfering. Assembly of bricks in foreground will slide back to enclose and shield equipment in the three chambers. Date: 1982. INEEL negative no. 82-6376 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

  19. Evaluating the High Asia Reanalysis (HAR) using Gauge-based and Satellite Precipitation Data over High Mountain Asia

    NASA Astrophysics Data System (ADS)

    Pangaluru, K.; Velicogna, I.; Ciraci, E.; Mohajerani, Y.

    2017-12-01

    The Indus, Ganges and Brahmaputra (IGB) basins supply water for both domestic and agricultural demands, the latter of which is the mainstay of Indian economy. Here, we use high-resolution Asia Refined Analysis (HAR) rainfall datasets to study the spatial and temporal behavior of rainfall over the mountainous areas of the Indus, Ganges and Brahmaputra (IGB) over the period from 2001 to 2014. The validation of High Asia Refined Analysis (HAR) precipitation data is carried out with observational (GPCP, CRU and CPC) and satellite (TRMM_3B43) datasets for the period. We find that the relative differences between the HAR model and the satellite and gauge-based datasets varies between -9% and 67% for the seasonal mean and between 1% and 26% for the annual mean for all basins. The correlation between the HAR model and the observational datasets lies between 0.5 and 0.9 for all seasons. Spatial variations and monthly magnitudes of gridded precipitation trends are calculated by using the Mann-Kendall (MK) test and the Thei-Sen approach (TSA) respectively. We found significant positive trends precipitation grids over the IGB basins in the annual and monsoon season time frames, as opposed to winter and falls seasons.

  20. Basement involved thrusts from Northwestern Maracaibo Basin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Audemard, F.

    1993-02-01

    The interpretation of seismic reflection profiles from northwestern Maracaibo Basin, north of the Palmar River, suggests a late Neogene age for all the structures located within the north-northeast trends of anticlinal belts. These folded structures appear to be ramp anticlines generated from basement involved thrusts. Such detachments are intercepted by conjugate systems of low-angle decollements decoupled from the thick shaly intervals of Cretaceous and Eocene age. The resulting configuration of these fault systems are related to a mechanic of deformation referred as [open quotes]fish tail[close quotes]. This structural style favors the superposition of structural traps at different levels. The superposedmore » reservoirs from La Paz, Mara, Sibucara, Mara Oeste, and Ensenada among others constitute superb examples of this style of deformation. Similar anticlinal structures are also observed to the southeast of the Basin in the Ceuta-Tomoporo area.« less

  1. Geophysically inferred structural and lithologic map of the precambrian basement in the Joplin 1 degree by 2 degrees Quadrangle, Kansas and Missouri

    USGS Publications Warehouse

    McCafferty, Anne E.; Cordell, Lindrith E.

    1992-01-01

    This report is an analysis of regional gravity and aeromagnetic data that was carried out as part of a Conterminuous United States Mineral Assessment Program (CUSMAP) study of the Joplin 1° X 2° quadrangle, Kansas and Missouri. It is one in a series of reports representing a cooperative effort between the U.S. Geological Survey, Kansas Geological Survey, and Missouri Department of Natural Resources, Division of Geology and Land Survey. The work presented here is part of a larger project whose goal is to assess the mineral resource potential of the Paleozoic sedimentary section and crystalline basement within the quadrangle. Reports discussing geochemical, geological, and various other aspects of the study area are included in this Miscellaneous Field Studies Map series as MF-2125-A through MF-2125-E. Geophysical interpretation of Precambrian crystalline basement lithology and structure is the focus of this report. The study of the crystalline basement is complicated by the lack of exposures due to the presence of a thick sequence of Phanerozoic sedimentary cover. In areas where there are no outcrops, the geologist must turn to other indirect methods to assist in an understanding of the basement. Previous investigations of the buried basement in this region used available drill hole data, isotope age information, and regional geophysical data (Sims, 1990; Denison and others, 1984; Bickford and others, 1986). These studies were regional in scope and were presented at state and multistate scales. The work documented here used recently collected detailed gravity and aeromagnetic data to enhance the regional geologic knowledge of the area. Terrace-density and terrace-magnetization maps were calculated from the gravity and aeromagnetic data, leading directly to inferred physical-property (density and magnetization) maps. Once these maps were produced, the known geology and drill-hole data were reconciled with the physical-property maps to form a refined structural and

  2. Basement inheritance and salt tectonics in the SE Barents Sea: Insights from new potential field data

    NASA Astrophysics Data System (ADS)

    Gernigon, L.; Broenner, M.; Dumais, M. A.; Gradmann, S.; Grønlie, A.; Nasuti, A.; Roberts, D.

    2017-12-01

    The tectonic evolution of the former `grey zone' between Russia and Norway has so far remained poorly constrained due to a lack of geophysical data. In 2014, we carried out a new aeromagnetic survey (BASAR-14) in the southern part of the new Norwegian offshore territory. Caledonian and Timanian structures, highlighted by the new potential field data, dominate the basement patterns and have exerted a strong influence on the structure and development of the overlying basins and basement highs. Clearly associated with NW-SE-oriented Timanian trends, the Tiddlybanken Basin represents an atypical sag basin that developed at the southern edge of the Fedynsky High. Regional extension and rapid sedimentation initiated the salt tectonics in the Barents Sea in the Early Triassic. Some of the pillows became diapiric during the Early Triassic and rejuvenated during subsequent Jurassic-Tertiary episodes of regional extension and/or compression. At present, quite a few large diapiric salt domes along the Nordkapp and Tiddlybanken basins are relatively shallow, locally reaching the seabed and thus show a clear bathymetric and magnetic signature. Quantitative modelling along 2D seismic transects was also carried out to constrain the structural and basement composition of the study area. The predominant NE-SW Mesozoic trend of the Nordkapp Basin represents a major crustal hinge zone between the Finnmark Platform, poorly affected by major crustal deformation, and the Bjarmeland Platform where Late Palaeozoic rifting controlled the widespread accumulation of salt deposits in Late Carboniferous-Early Permian time. The entire structure and segmentation of the Nordkapp Basin have been influenced by the inherited basement configuration highlighted by the new aeromagnetic data. Both the Nordkapp and the Tiddlybanken basins appear to lie at the edge of a peculiar thick and rigid crustal feature that coincides with a highly magnetic region. The abrupt termination of the eastern Nordkapp

  3. Lysyl Hydroxylase 3 Localizes to Epidermal Basement Membrane and Is Reduced in Patients with Recessive Dystrophic Epidermolysis Bullosa

    PubMed Central

    Watt, Stephen A.; Dayal, Jasbani H. S.; Wright, Sheila; Riddle, Megan; Pourreyron, Celine; McMillan, James R.; Kimble, Roy M.; Prisco, Marco; Gartner, Ulrike; Warbrick, Emma; McLean, W. H. Irwin; Leigh, Irene M.; McGrath, John A.; Salas-Alanis, Julio C.; Tolar, Jakub; South, Andrew P.

    2015-01-01

    Recessive dystrophic epidermolysis bullosa (RDEB) is caused by mutations in COL7A1 resulting in reduced or absent type VII collagen, aberrant anchoring fibril formation and subsequent dermal-epidermal fragility. Here, we identify a significant decrease in PLOD3 expression and its encoded protein, the collagen modifying enzyme lysyl hydroxylase 3 (LH3), in RDEB. We show abundant LH3 localising to the basement membrane in normal skin which is severely depleted in RDEB patient skin. We demonstrate expression is in-part regulated by endogenous type VII collagen and that, in agreement with previous studies, even small reductions in LH3 expression lead to significantly less secreted LH3 protein. Exogenous type VII collagen did not alter LH3 expression in cultured RDEB keratinocytes and we show that RDEB patients receiving bone marrow transplantation who demonstrate significant increase in type VII collagen do not show increased levels of LH3 at the basement membrane. Our data report a direct link between LH3 and endogenous type VII collagen expression concluding that reduction of LH3 at the basement membrane in patients with RDEB will likely have significant implications for disease progression and therapeutic intervention. PMID:26380979

  4. Dillon cutoff-Basement-involved tectonic link between the disturbed belt of west-central Montana and the overthrust belt of extreme southwestern Montana

    NASA Astrophysics Data System (ADS)

    O'Neill, J. Michael; Schmidt, Christopher J.; Genovese, Paul W.

    1990-11-01

    The front of the Cordilleran fold and thrust belt in western Montana follows the disturbed belt in the north, merges with the southwest Montana transverse zone in the west-central part of the region, and in southwestern Montana is marked by a broad zone characterized by complex interaction between thrust belt structures and basement uplifts. The front margin of the thrust belt in Montana reflects mainly thin-skinned tectonic features in the north, an east-trending lateral ramp that curves southwest in the central part into the Dillon cutoff, an oblique-slip, thick-skinned displacement transfer zone that cuts through basement rocks of the Lima recess, and a zone of overlap between thin- and thick-skinned thrusts in extreme southwestern Montana. The transverse ramp and basement-involved thrust faults are controlled by Proterozoic structures.

  5. The Impact of Harness Impedance on Hall Thruster Discharge Oscillations

    NASA Technical Reports Server (NTRS)

    Pinero, Luis R.

    2017-01-01

    Hall thrusters exhibit characteristic discharge voltage and current oscillations during steady-state operation. The lower frequency breathing-mode current oscillations are inherent to each thruster and could impact thruster operation and power processing unit (PPU) design. The design of the discharge output filter, in particular, the output capacitor is important because it supplies the high peak current oscillations that the thruster demands. However, space-rated, high-voltage capacitors are not readily available and can have significant mass and volume. So, it is important for a PPU designer to know what is the minimum amount of capacitance required to operate a thruster. Through Simulation Program with Integrated Circuit Emphasis modeling and electrical measurements on the Hall Effect Rocket with Magnetic Shielding thruster, it was shown that the harness impedance between the power supply and the thruster is the main contributor towards generating voltage ripple at the thruster. Also, increasing the size of the discharge filter capacitor, as previously implemented during thruster tests, does not reduce the voltage oscillations. The electrical characteristics of the electrical harness between the discharge supply and the thruster is crucial to system performance and could have a negative impact on performance, life and operation.

  6. The Impact of Harness Impedance on Hall Thruster Discharge Oscillations

    NASA Technical Reports Server (NTRS)

    Pinero, Luis R.

    2017-01-01

    Hall thrusters exhibit characteristic discharge voltage and current oscillations during steady-state operation. The lower frequency breathing-mode current oscillations are inherent to each thruster and could impact thruster operation and PPU design. The design of the discharge output filter, in particular, the output capacitor is important because it supplies the high peak current oscillations that the thruster demands. However, space-rated, high-voltage capacitors are not readily available and can have significant mass and volume. So, it is important for a PPU designer to know what is the minimum amount of capacitance required to operate a thruster. Through SPICE modeling and electrical measurements on the Hall Effect Rocket with Magnetic Shielding (HERMeS) thruster, it was shown that the harness impedance between the power supply and the thruster is the main contributor towards generating voltage ripple at the thruster. Also, increasing the size of the discharge filter capacitor, as previously implemented during thruster tests, does not reduce the voltage oscillations. The electrical characteristics of the electrical harness between the discharge supply and the thruster is crucial to system performance and could have a negative impact on performance, life and operation.

  7. Thick-skinned tectonics in a Late Cretaceous-Neogene intracontinental belt (High Atlas Mountains, Morocco): The flat-ramp fault control on basement shortening and cover folding

    NASA Astrophysics Data System (ADS)

    Fekkak, A.; Ouanaimi, H.; Michard, A.; Soulaimani, A.; Ettachfini, E. M.; Berrada, I.; El Arabi, H.; Lagnaoui, A.; Saddiqi, O.

    2018-04-01

    Most of the structural studies of the intracontinental High Atlas belt of Morocco have dealt with the central part of the belt, whose basement does not crop out. Here we study the Alpine deformation of the North Subatlas Zone, which is the part of the Western High Atlas (WHA) Paleozoic Massif that involves both Paleozoic basement units and remnants of their Mesozoic-Cenozoic cover formations. Our aim is to better constrain the geometry and kinematics of the basement faults during the Alpine shortening. Based on detail mapping, satellite imagery and field observations, we describe an array of sub-equatorial, transverse and oblique faults between the WHA Axial Zone and the Haouz Neogene basin. They define a mosaic of basement blocks pushed upon one another and upon the Haouz basement along the North Atlas Fault (NAF). The Axial Zone makes up the hanging-wall of the Adassil-Medinet Fault (AMF) south of this mosaic. The faults generally presents flat-ramp-flat geometry linked to the activation of multiple décollement levels, either within the basement where its foliation is subhorizontal or within favourable cover formations (Jurassic evaporites, Lower Cretaceous silty red beds, Upper Cretaceous evaporitic marls, Neogene basal argillites). The occurrence of the North Atlas detachment (NAD) allowed folded pop-up units to develop in front of the propagating NAF. Shortening began as early as the Campanian-Maastrichtian along the AMF. The direction of the maximum horizontal stress rotated from NNE-SSW to NNW-SSE from the Maastrichtian-Paleocene to the Neogene. The amount of shortening reaches 20% in the Azegour transect. This compares with the shortening amount published for the central-eastern High Atlas, suggesting that similar structures characterize the Paleozoic basement all along the belt. The WHA thick-skinned tectonics evokes that of the frontal Sevier belt and of the external Western Alps, although with a much minor pre-inversion burial.

  8. Hydrocarbons in New Guinea, controlled by basement fabric, Mesozoic extension and Tertiary convergent margin tectonics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hill, K.C.; Kendrick, R.D.; Crowhurst, P.V.

    1996-01-01

    Most models for the tectonic evolution of New Guinea involve Early and Late Miocene arc-continent collisions, creating an orogenic belt. Structural trends and prospectivity are then analyzed in terms of belts across the country; the Fold Belt (with the discovered oil and gas fields), the Mobile Belt and the accreted arcs. This model inhibits realistic assessment of prospectivity. It now appears the Mobile Belt formed by Oligocene compression then by Early Miocene extension, related to slab-rollback, that unroofed metamorphic core complexes adjacent to starved half-grabens. The grabens filled in the Middle Miocene and were largely transported intact during the Pliocenemore » arc-collision. Early Miocene reefs and hypothesized starved basin source rocks create a viable play throughout northern New Guinea as in the Salawati Basin. The Pliocene clastic section is locally prospective due to overthrusting and deep burial. Within the Fold Belt, the site and types of oil and gas fields are largely controlled by the basement architecture. This controlled the transfer zones and depocentres during Mesozoic extension and the location of major basement uplifts during compression. In PNG, the Bosavi lineament separates an oil province from a gas province. In Irian Jaya the transition from a relatively competent sequence to a rifted sequence west of [approx]139[degrees]E may also be a gas-oil province boundary. Understanding, in detail, the compartmentalization of inverted blocks and areas of thin-skinned thrusting, controlled by the basement architecture, will help constrain hydrocarbon prospectivity.« less

  9. Hydrocarbons in New Guinea, controlled by basement fabric, Mesozoic extension and Tertiary convergent margin tectonics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hill, K.C.; Kendrick, R.D.; Crowhurst, P.V.

    1996-12-31

    Most models for the tectonic evolution of New Guinea involve Early and Late Miocene arc-continent collisions, creating an orogenic belt. Structural trends and prospectivity are then analyzed in terms of belts across the country; the Fold Belt (with the discovered oil and gas fields), the Mobile Belt and the accreted arcs. This model inhibits realistic assessment of prospectivity. It now appears the Mobile Belt formed by Oligocene compression then by Early Miocene extension, related to slab-rollback, that unroofed metamorphic core complexes adjacent to starved half-grabens. The grabens filled in the Middle Miocene and were largely transported intact during the Pliocenemore » arc-collision. Early Miocene reefs and hypothesized starved basin source rocks create a viable play throughout northern New Guinea as in the Salawati Basin. The Pliocene clastic section is locally prospective due to overthrusting and deep burial. Within the Fold Belt, the site and types of oil and gas fields are largely controlled by the basement architecture. This controlled the transfer zones and depocentres during Mesozoic extension and the location of major basement uplifts during compression. In PNG, the Bosavi lineament separates an oil province from a gas province. In Irian Jaya the transition from a relatively competent sequence to a rifted sequence west of {approx}139{degrees}E may also be a gas-oil province boundary. Understanding, in detail, the compartmentalization of inverted blocks and areas of thin-skinned thrusting, controlled by the basement architecture, will help constrain hydrocarbon prospectivity.« less

  10. Quality of harness fit for normal and low birthweight infants observed among newborns in infant car seats.

    PubMed

    Brown, Julie; Sinn, John Kam Hung; Chua, Aileen; Clarke, Elizabeth Clare

    2017-04-01

    Child restraint fit is important for crash protection. For newborns, standards universally require a rear-facing restraint and some upper limit on size, but historically there has been no specification of a lower design limit and there is concern over whether low birthweight infants (LBW) are adequately restrained. The aim of this study was to determine the quality of harness fit for newborns of low and normal weight in a range of modern child restraints. A convenience sample of infants (1.657-4.455 kg) were recruited from the postnatal ward and special care nursery <1 week from discharge. Infants (n=84) were assessed for harness fit in rear-facing-only restraints, convertible rear/forward restraints and a subset were assessed in a restraint specifically designed to accommodate LBW infants. Measures of harness fit were based on shoulder strap, crotch strap and buckle positioning. Less than 20% of infants achieved good harness fit, regardless of whether they were categorised as low (<2.5 kg) or normal weight. Rear-facing-only restraints were less likely to provide good fit than convertible restraints, in all measures of fit other than shoulder strap width. The proportions of infants achieving good fit were greater in the restraint designed for LBW infants than other restraint types. Poor accommodation continues to be a problem for LBW infants but is rectified in specifically designed restraints. Better specification of harness configuration for all rearward-facing restraints may be required to ensure adequate accommodation of normal birthweight infants. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  11. A test harness for accelerating physics parameterization advancements into operations

    NASA Astrophysics Data System (ADS)

    Firl, G. J.; Bernardet, L.; Harrold, M.; Henderson, J.; Wolff, J.; Zhang, M.

    2017-12-01

    The process of transitioning advances in parameterization of sub-grid scale processes from initial idea to implementation is often much quicker than the transition from implementation to use in an operational setting. After all, considerable work must be undertaken by operational centers to fully test, evaluate, and implement new physics. The process is complicated by the scarcity of like-to-like comparisons, availability of HPC resources, and the ``tuning problem" whereby advances in physics schemes are difficult to properly evaluate without first undertaking the expensive and time-consuming process of tuning to other schemes within a suite. To address this process shortcoming, the Global Model TestBed (GMTB), supported by the NWS NGGPS project and undertaken by the Developmental Testbed Center, has developed a physics test harness. It implements the concept of hierarchical testing, where the same code can be tested in model configurations of varying complexity from single column models (SCM) to fully coupled, cycled global simulations. Developers and users may choose at which level of complexity to engage. Several components of the physics test harness have been implemented, including a SCM and an end-to-end workflow that expands upon the one used at NOAA/EMC to run the GFS operationally, although the testbed components will necessarily morph to coincide with changes to the operational configuration (FV3-GFS). A standard, relatively user-friendly interface known as the Interoperable Physics Driver (IPD) is available for physics developers to connect their codes. This prerequisite exercise allows access to the testbed tools and removes a technical hurdle for potential inclusion into the Common Community Physics Package (CCPP). The testbed offers users the opportunity to conduct like-to-like comparisons between the operational physics suite and new development as well as among multiple developments. GMTB staff have demonstrated use of the testbed through a

  12. 14 CFR 29.785 - Seats, berths, litters, safety belts, and harnesses.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... serious injury in an emergency landing as a result of the inertial factors specified in § 29.561(b) and dynamic conditions specified in § 29.562. (b) Each occupant must be protected from serious head injury by a safety belt plus a shoulder harness that will prevent the head from contacting any injurious...

  13. 14 CFR 29.785 - Seats, berths, litters, safety belts, and harnesses.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... serious injury in an emergency landing as a result of the inertial factors specified in § 29.561(b) and dynamic conditions specified in § 29.562. (b) Each occupant must be protected from serious head injury by a safety belt plus a shoulder harness that will prevent the head from contacting any injurious...

  14. 14 CFR 29.785 - Seats, berths, litters, safety belts, and harnesses.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... serious injury in an emergency landing as a result of the inertial factors specified in § 29.561(b) and dynamic conditions specified in § 29.562. (b) Each occupant must be protected from serious head injury by a safety belt plus a shoulder harness that will prevent the head from contacting any injurious...

  15. 14 CFR 29.785 - Seats, berths, litters, safety belts, and harnesses.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... serious injury in an emergency landing as a result of the inertial factors specified in § 29.561(b) and dynamic conditions specified in § 29.562. (b) Each occupant must be protected from serious head injury by a safety belt plus a shoulder harness that will prevent the head from contacting any injurious...

  16. ETR BUILDING, TRA642, INTERIOR. BASEMENT. CAMERA IS AT MIDPOINT OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ETR BUILDING, TRA-642, INTERIOR. BASEMENT. CAMERA IS AT MIDPOINT OF SOUTH CORRIDOR AND FACES EAST, OPPOSITE DIRECTION FROM VIEWS ID-33-G-98 AND ID-33-G-99. STEEL DOOR AT LEFT OPENS BY ROLLING IT INTO CORRIDOR ON RAILS. TANK AT FAR END OF CORRIDOR IS EMERGENCY CORE COOLING CATCH TANK FOR A TEST LOOP. INL NEGATIVE NO. HD46-30-4. Mike Crane, Photographer, 2/2005 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  17. High resolution immunoelectron microscopic localization of functional domains of laminin, nidogen, and heparan sulfate proteoglycan in epithelial basement membrane of mouse cornea reveals different topological orientations.

    PubMed

    Schittny, J C; Timpl, R; Engel, J

    1988-10-01

    Thin and ultrathin cryosections of mouse cornea were labeled with affinity-purified antibodies directed against either laminin, its central segments (domain 1), the end of its long arm (domain 3), the end of one of its short arms (domain 4), nidogen, or low density heparan sulfate proteoglycan. All basement membrane proteins are detected by indirect immunofluorescence exclusively in the epithelial basement membrane, in Descemet's membrane, and in small amorphous plaques located in the stroma. Immunoelectron microscopy using the protein A-gold technique demonstrated laminin domain 1 and nidogen in a narrow segment of the lamina densa at the junction to the lamina lucida within the epithelial basement membrane. Domain 3 shows three preferred locations at both the cellular and stromal boundaries of the epithelial basement membrane and in its center. Domain 4 is located predominantly in the lamina lucida and the adjacent half of the lamina densa. The low density heparan sulfate proteoglycan is found all across the basement membrane showing a similar uniform distribution as with antibodies against the whole laminin molecule. In Descemet's membrane an even distribution was found with all these antibodies. It is concluded that within the epithelial basement membrane the center of the laminin molecule is located near the lamina densa/lamina lucida junction and that its long arm favors three major orientations. One is close to the cell surface indicating binding to a cell receptor, while the other two are directed to internal matrix structures. The apparent codistribution of laminin domain 1 and nidogen agrees with biochemical evidence that nidogen binds to this domain.

  18. Laminin- and basement membrane-polycaprolactone blend nanofibers as a scaffold for regenerative medicine.

    PubMed

    Neal, Rebekah A; Lenz, Steven M; Wang, Tiffany; Abebayehu, Daniel; Brooks, Benjamin P C; Ogle, Roy C; Botchwey, Edward A

    2014-09-01

    Mimicking one or more components of the basement membrane (BM) holds great promise for overcoming insufficiencies in tissue engineering therapies. We have electrospun laminin nanofibers (NFs) isolated from the murine Engelbreth-Holm Swarm (EHS) tumor and evaluated them as a scaffold for embryonic stem cell culture. Seeded human embryonic stem cells were found to better maintain their undifferentiated, colony environment when cultured on laminin NFs compared to laminin mats, with 75% remaining undifferentiated on NFs. Mouse embryonic stem cells cultured on 10% laminin-polycaprolactone (PCL) NFs maintained their colony formation for twice as long without passage compared to those on PCL or gelatin substrates. In addition, we have established a protocol for electrospinning reconstituted basement membrane aligned (RBM)-PCL NFs within 10° of angular deviation. Neuron-like PC12 cells show significantly greater attachment (p < 0.001) and percentage of neurite-extending cells in vitro on 10% RBM-PCL NFs when compared to 1% and 0% RBM-PCL NFs (p < 0.015 and p < 0.001, respectively). Together, these results implicate laminin- and RBM-PCL scaffolds as a promising biomimetic substrate for regenerative medicine applications.

  19. Convective influx/glymphatic system: tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways.

    PubMed

    Albargothy, Nazira J; Johnston, David A; MacGregor-Sharp, Matthew; Weller, Roy O; Verma, Ajay; Hawkes, Cheryl A; Carare, Roxana O

    2018-05-12

    Tracers injected into CSF pass into the brain alongside arteries and out again. This has been recently termed the "glymphatic system" that proposes tracers enter the brain along periarterial "spaces" and leave the brain along the walls of veins. The object of the present study is to test the hypothesis that: (1) tracers from the CSF enter the cerebral cortex along pial-glial basement membranes as there are no perivascular "spaces" around cortical arteries, (2) tracers leave the brain along smooth muscle cell basement membranes that form the Intramural Peri-Arterial Drainage (IPAD) pathways for the elimination of interstitial fluid and solutes from the brain. 2 μL of 100 μM soluble, fluorescent fixable amyloid β (Aβ) were injected into the CSF of the cisterna magna of 6-10 and 24-30 month-old male mice and their brains were examined 5 and 30 min later. At 5 min, immunocytochemistry and confocal microscopy revealed Aβ on the outer aspects of cortical arteries colocalized with α-2 laminin in the pial-glial basement membranes. At 30 min, Aβ was colocalised with collagen IV in smooth muscle cell basement membranes in the walls of cortical arteries corresponding to the IPAD pathways. No evidence for drainage along the walls of veins was found. Measurements of the depth of penetration of tracer were taken from 11 regions of the brain. Maximum depths of penetration of tracer into the brain were achieved in the pons and caudoputamen. Conclusions drawn from the present study are that tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways. The exit route is along IPAD pathways in which Aβ accumulates in cerebral amyloid angiopathy (CAA) in Alzheimer's disease. Results from this study suggest that CSF may be a suitable route for delivery of therapies for neurological diseases, including CAA.

  20. New Padded Harness for Self-Acquisition of Resting 12-Lead ECGs

    NASA Technical Reports Server (NTRS)

    Schlegel, T. T.; Rood, A. T.

    2011-01-01

    We have developed a dry-electrode harness that permits easy, rapid, and unsupervised self-acquisition of resting 12-lead ECGs without the use of any disposables. Various other advantageous features of the harness include: 1) padded or inflatable cushions at the lateral sides of the torso that function to press the left arm (LA) and right arm (RA) dry electrodes mounted on cushions against sideward (as shown in the Figure below) or downward-rested arms of the subject; 2) sufficient distal placement of the arm electrodes with good abutment and without the need for adhesives, straps, bands, bracelets, or gloves on the arms; 3) padding over the sternum to avoid "tenting" in the V1 through V3 (and V3R, when present) electrode positions; 4) easy-to-don, one-piece design with an adjustable single point of connection and an adjustable shoulder strap; and 5) Lund or "modified Lund" placement of the dry electrodes, the results of which more effectively reproduce results from "standard" 12-lead ECG placements than do results from Mason-Likar lead placements.

  1. Fault-Slip Data Analysis and Cover Versus Basement Fracture Patterns - Implications for Subsurface Technical Processes in Thuringia, Germany

    NASA Astrophysics Data System (ADS)

    Kasch, N.; Kley, J.; Navabpour, P.; Siegburg, M.; Malz, A.

    2014-12-01

    Recent investigations in Thuringia, Central Germany, focus on the potential for carbon sequestration, groundwater supply and geothermal energy. We report on the results of an integrated fault-slip data analysis to characterize the geometries and kinematics of systematic fractures in contrasting basement and cover rock lithologies. The lithostratigraphy of the area comprises locally exposed crystalline rocks and intermittently overlying Permian volcanic and clastic sedimentary rocks, together referred to as basement. A Late Permian sequence of evaporites, carbonates and shale constitutes the transition to the continuous sedimentary cover of Triassic age. Major NW-SE-striking fault zones and minor NNE-SSW-striking faults affect this stratigraphic succession. These characteristic narrow deforming areas (< 3 km width) build a dense network of individual fault strands with a close juxtaposition to wider (> 15 km) non-deforming areas suggesting localized zones of mechanical weakness, which can be confirmed by the frequent reactivation of single fault strands. Along the major fault zones, the basement and cover contain dominant inclined to sub-vertical NW-SE-striking fractures. These fractures indicate successive normal, dextral strike-slip and reverse senses of slip, evidencing events of NNE-SSW extension and contraction. Another system of mostly sub-vertical NNW-SSE- and NE-SW-striking conjugate strike-slip faults mainly developed within the cover implies NNE-SSW contraction and WNW-ESE extension. Earthquake focal mechanisms and in-situ stress measurements reveal a NW-SE trend for the modern SHmax. Nevertheless, fractures and fault-slip indicators are rare in the non-deforming areas, which characterizes Thuringia as a dual domain of (1) large unfractured areas and (2) narrow zones of high potential for technical applications. Our data therefore provide a basis for estimation of slip and dilation tendency of the contrasting fractures in the basement and cover under the

  2. Detection of microinvasion in vulvar and cervical intraepithelial neoplasia using double immunostaining for cytokeratin and basement membrane components.

    PubMed

    Rush, Demaretta; Hyjek, Elizabeth; Baergen, Rebecca N; Ellenson, Lora H; Pirog, Edyta C

    2005-06-01

    Identification of early invasion in vulvar intraepithelial neoplasia 3 (VIN 3) and cervical intraepithelial neoplasia 3 (CIN 3) may be difficult with the use of routine hematoxylin-eosin staining. Presence of obscuring inflammation and tangential tissue sectioning are the most common diagnostic pitfalls. To examine the utility of double immunostaining for cytokeratin-collagen IV or cytokeratin-laminin in the detection of early invasion in VIN 3 and CIN 3. The study group consisted of 10 cases of "VIN 3, suspicious for invasion" and 10 cases of "CIN 3, suspicious for invasion." The negative control group consisted of VIN 3 (n = 15) and CIN 3 (n = 10). The positive control group consisted of cases of invasive vulvar carcinoma (n = 11) and invasive cervical carcinoma (n = 25). All cases were double immunostained for cytokeratin and collagen IV and, in a separate reaction, for cytokeratin and laminin. The continuity of the basement membrane and the presence of stromal invasion were assessed in the stained sections. The staining for collagen IV and laminin yielded identical results. A well-defined, continuous basement membrane was visualized in all cases of VIN 3 and CIN 3. A discontinuous or absent basement membrane was observed around the malignant cells on the invasive tumor front in all cases of vulvar and cervical carcinoma. In 2 of 10 cases of VIN 3, suspicious for invasion and in 4 of 10 cases of CIN 3, suspicious for invasion definitive foci of microinvasion were identified with the use of double immunostaining. A well-defined, continuous basement membrane was present in the remaining cases "suspicious for invasion." Double immunostaining for cytokeratin- collagen IV or cytokeratin-laminin is useful for evaluation of early invasion in equivocal cases of VIN 3 and CIN 3.

  3. Peering into the deep: Illuminating the crustal evolution of the Eucla basement and its relationship to the Albany-Fraser Orogen of southwest Australia.

    NASA Astrophysics Data System (ADS)

    Hartnady, Michael; Kirkland, Chris; Clark, Chris; Spaggiari, Catherine; Smithies, Hugh

    2017-04-01

    The Albany-Fraser Orogen is a 1200 km long east to northeasterly trending Palaeoproterozoic to Mesoproterozoic orogenic belt that defines the southern to southeastern margin of the West Australian Craton (WAC). The belt records a long and complex geological history spanning the break-up of Nuna between 2000 and 1700 Ma and amalgamation of Rodinia between 1300 and 1000 Ma. Recent geochronological, geochemical and isotopic work has shown that the Albany-Fraser Orogen formed through a protracted period of reworking of the margin of the Archean Yilgarn Craton (part of the WAC) with various additions of mantle-derived material. The Cretaceous Bight and Cenozoic Eucla Basins partially overlie the northeastern part of the Albany-Fraser Orogen and completely cover 1000 km of crystalline basement (the Eucla basement) that separates the belt from the South Australian Craton. This basement constitutes the glue between the major building blocks of Proterozoic Australia, yet, its geological history is poorly understood. New drill cores penetrating the basement have intersected interlayered granitic and gabbroic rocks that yield U-Pb zircon dates that are dissimilar to any magmatic ages from units within the adjoining Albany-Fraser Orogen, with the exception of the youngest, 1190-1125 Ma magmatic suite. In addition, mantle-like hafnium and neodymium isotopic signatures indicate that the rocks of the Eucla basement are dominated by new juvenile addition, and may represent an allochthonous terrane of oceanic heritage. New ɛHf contour maps for the Albany-Fraser Orogen and Eucla basement highlight this difference. Time-slicing the isotopic dataset reveals a pattern of Palaeoproterozoic juvenile magmatism sub-perpendicular to the present day structural grain in the belt. If this marks the presence of an older lithospheric structure then it demonstrates the power that time-constrained isotopic mapping provides for illuminating lithospheric architecture through time. This may be

  4. A COMPARISON OF WINTER SHORT-TERM AND ANNUAL AVERAGE RADON MEASUREMENTS IN BASEMENTS OF A RADON-PRONE REGION AND EVALUATION OF FURTHER RADON TESTING INDICATORS

    PubMed Central

    Barros, Nirmalla G.; Steck, Daniel J.; Field, R. William

    2014-01-01

    The primary objective of this study was to investigate the temporal variability between basement winter short-term (7 to 10 days) and basement annual radon measurements. Other objectives were to test the short-term measurement’s diagnostic performance at two reference levels and to evaluate its ability to predict annual average basement radon concentrations. Electret ion chamber (short-term) and alpha track (annual) radon measurements were obtained by trained personnel in Iowa residences. Overall, the geometric mean of the short-term radon concentrations (199 Bq m−3) was slightly greater than the geometric mean of the annual radon concentrations (181 Bq m−3). Short-term tests incorrectly predicted that the basement annual radon concentrations would be below 148 Bq m−3 12% of the time and 2% of the time at 74 Bq m−3. The short-term and annual radon concentrations were strongly correlated (r=0.87, p<0.0001). The foundation wall material of the basement was the only significant factor to have an impact on the absolute difference between the short-term and annual measurements. The findings from this study provide evidence of a substantially lower likelihood of obtaining a false negative result from a single short-term test in a region with high indoor radon potential when the reference level is lowered to 74 Bq m−3. PMID:24670901

  5. Live-cell confocal microscopy and quantitative 4D image analysis of anchor cell invasion through the basement membrane in C. elegans

    PubMed Central

    Kelley, Laura C.; Wang, Zheng; Hagedorn, Elliott J.; Wang, Lin; Shen, Wanqing; Lei, Shijun; Johnson, Sam A.; Sherwood, David R.

    2018-01-01

    Cell invasion through basement membrane (BM) barriers is crucial during development, leukocyte trafficking, and for the spread of cancer. Despite its importance in normal and diseased states, the mechanisms that direct invasion are poorly understood, in large part because of the inability to visualize dynamic cell-basement membrane interactions in vivo. This protocol describes multi-channel time-lapse confocal imaging of anchor cell invasion in live C. elegans. Methods presented include outline slide preparation and worm growth synchronization (15 min), mounting (20 min), image acquisition (20-180 min), image processing (20 min), and quantitative analysis (variable timing). Images acquired enable direct measurement of invasive dynamics including invadopodia formation, cell membrane protrusions, and BM removal. This protocol can be combined with genetic analysis, molecular activity probes, and optogenetic approaches to uncover molecular mechanisms underlying cell invasion. These methods can also be readily adapted for real-time analysis of cell migration, basement membrane turnover, and cell membrane dynamics by any worm laboratory. PMID:28880279

  6. Raetrad model extensions for radon entry into multi-level buildings with basements or crawl spaces.

    PubMed

    Nielson, K K; Rogers, V C; Rogers, V; Holt, R B

    1997-10-01

    The RAETRAD model was generalized to characterize radon generation and movement from soils and building materials into multi-level buildings with basements or crawl spaces. With the generalization, the model retains its original simplicity and ease of use. The model calculates radon entry rates that are consistent with measurements published for basement test structures at Colorado State University, confirming approximately equal contributions from diffusion and pressure-driven air flow at indoor-outdoor air pressure differences of deltaP(i-o) = -3.5 Pa. About one-fourth of the diffusive radon entry comes from concrete slabs and three-fourths comes from the surrounding soils. Calculated radon entry rates with and without a barrier over floor-wall shrinkage cracks generally agree with Colorado State University measurements when a sustained pressure of deltaP(i-o) = -2 Pa is used to represent calm wind (<1 m s(-1)) conditions. Calculated radon distributions in a 2-level house also are consistent with published measurements and equations.

  7. Harnessing dendritic cells in inflammatory skin diseases

    PubMed Central

    Chu, Chung-Ching; Di Meglio, Paola; Nestle, Frank O.

    2011-01-01

    The skin immune system harbors a complex network of dendritic cells (DCs). Recent studies highlight a diverse functional specialization of skin DC subsets. In addition to generating cellular and humoral immunity against pathogens, skin DCs are involved in tolerogenic mechanisms to ensure the maintenance of immune homeostasis, as well as in pathogenesis of chronic inflammation in the skin when excessive immune responses are initiated and unrestrained. Harnessing DCs by directly targeting DC-derived molecules or selectively modulate DC subsets is a convincing strategy to tackle inflammatory skin diseases. In this review we discuss recent advances underlining the functional specialization of skin DCs and discuss the potential implication for future DC-based therapeutic strategies. PMID:21295490

  8. Neoproterozoic complexes of the shelf cover of the Dzabkhan terrane basement in the Central Asian Orogenic Belt

    NASA Astrophysics Data System (ADS)

    Kozakov, I. K.; Kuznetsov, A. B.; Erdenegargal, Ch.; Salnikova, E. B.; Anisimova, I. V.; Plotkina, Ju. V.; Fedoseenko, A. M.

    2017-09-01

    The formation stages of high-grade metamorphic complexes and the related granitoids of the Dzabkhan terrane basement are considered. The age data (U-Pb method, TIMS) of zircons from the trondhjemite block of the eastern part of the Dzabkhan terrane, which is directly overlain by the dolomite sequence of the Tsagaan Oloom Formation, are given. Trondhjemites yield the U-Pb zircon age of 862 ± 3 Ma. In their structural position, they are assigned to typical postmetamorphic formations that determine the formation and cratonization of rocks of the host block. The geochronological study of trondhjemites gives grounds to distinguish fragments of the continental crust in the Dzabkhan terrane basement, the formation of which occurred at different periods of time: ˜860 and ˜790 Ma. Geological-geochronological and Sm‒Nd isotope-geochemical studies indicate that the Dzabkhan terrane basement is not a single block of the Early Precambrian continental crust, but a composite terrane, comprising Neoproterozoic ensialic and island-arc structural and compositional complexes. Correlation of Sr isotopic characteristics with the 87Sr/86Sr variation curve in the Neoproterozoic and Cambrian seawater shows that carbonate deposits accumulated at the eastern margin of the Dzabkhan terrane near the end of the Neoproterozoic, 700-550 Ma, and in the central part of the terrane in the Early Cambrian, 540-530 Ma.

  9. Basement depth and sedimentary infill from deep seismic reflection data at the western tip of the offshore Corinth Rift

    NASA Astrophysics Data System (ADS)

    Beckers, Arnaud; Tripsanas, Efthymios; Hubert-Ferrari, Aurélia; Beck, Christian; Sakellariou, Dimitris

    2015-04-01

    The Corinth rift is a young continental rift located in central Greece. The active part of the rift forms an E-W striking depression - the Gulf of Corinth - that is the deepest in its central part. Extensive seismic surveys have imaged the basin's basement and allowed to estimate the total extension across most of the Gulf except its western tip. Extension is high in the central part and decreases westward and eastward, as reflected in the present-day bathymetry. Two decades of GPS measurements have shown that the extension rate increases westwards from ~5 to 10-15 mm yr-1, but this is not consistent with the long term pattern. However, no data allowed so far to estimate the basement depth at the western tip of the Gulf, where the geodetic extension rate is the largest. Such data would allow to check the apparent inconsistency between the present rate and the long-term estimates of crustal extension. We present here an unpublished multichannel seismic line dating from 1979 and crossing the western tip of the Gulf of Corinth. The line is 22 km long and strikes WNW-ESE, from the Mornos delta to the West-Channel fault. A Maxipulse source has been used, allowing to image the basement below the synrift sedimentary infill. To the east, a ~1.6 km deep basin is imaged between the southern margin of the Gulf and an inactive south-dipping fault located between the Aigion and the Trizonia faults. The sedimentary infill consists in an alternation between basin-focused bodies made of incoherent reflections and more extensive high-amplitude reflectors. Attributing this alternation to eustatic variations give an age of 300-350 ka to the oldest well imaged deposits. Northwest of the Trizonia fault, the basement is imaged at shallower depth, i.e. ~450 m. The western tip of the seismic line reaches the Mornos delta, close to the northern shoreline. There, the depth to the basement is larger, reaching ~1.2 km. The infill is made of 3 units : on the basement lies a thin unit of

  10. Geo-Thermochronometric Insights on the Cycladic Basement and Cycladic Blueschist Unit Contact in the Southern Cyclades, Ios Island, Greece

    NASA Astrophysics Data System (ADS)

    Flansburg, M. E.; Stockli, D. F.; Poulaki, E. M.; Soukis, K. I.

    2017-12-01

    The North Cycladic Detachment System, the West Cycladic Detachment System, and the Naxos-Paros Detachment accommodated large-scale Oligo-Miocene exhumation in the backarc of the retreating Hellenic subduction zone. While bivergent detachment faults in the northern and western Cyclades are either contained within the Cycladic Blueschist Unit (CBU) or at the CBU-Upper Unit interface, the sheared contact between the CBU and the underlying Cycladic Basement in the southern Cyclades (Ios) has been debated for over 30 years, largely due to the ambiguous coexistence of both top-to-the-N and top-to-the-S shear sense indicators and a lack of robust timing information. Reliable chronostratigraphic and thermal history constraints allow us to test whether the contact is a low-angle normal fault-possibly part of a larger detachment system-or the South Cycladic Thrust by placing absolute ages on deformation, determining older over younger relationships or vice versa, and quantifying possible differential exhumation during Cenozoic extension. Zircon U-Pb dating for the granitic Basement core of Ios gave Carboniferous-Permian age and shows that surrounding Basement metasedimentary units can be divided into two groups based on detrital zircon signatures. An older group of metasedimentary rocks have maximum depositional ages (MDAs) ranging from 450 Ma to 354 Ma and predate the intrusions, and late Permian Basement paragneisses are younger than the intrusions and likely originally deposited unconformably on the older units. Samples from the CBU in northern Ios yielded MDAs ranging from Mid-Jurassic to Late Cretaceous and appear to be repeated due to either thrusting or subduction accretion and exhibit older over younger relationships. MDA data from mapped CBU at the southern end of Ios yielded Ordovician to Permian ages, calling into question their assignment as CBU, while also revealing older over younger relationships. Zircon (U-Th)/He ages for the Basement and the CBU on Ios are 9

  11. New Constraints on the Extent of Paleoproterozoic and Archean Basement in the Northwest U.S. Cordillera

    NASA Astrophysics Data System (ADS)

    Brewer, R. A.; Vervoort, J.; Lewis, R. S.; Gaschnig, R. M.; Hart, G.

    2008-12-01

    The Laurentian basement west of the Wyoming craton in southwest Montana and northern Idaho has been interpreted as a collage of Archean and Proterozoic terranes which accreted to the North American craton and incorporated into Laurentia at ~ 1.86 Ga [1]. This basement and the geometry of the Archean and Proterozoic crust are poorly understood due to coverage by metasediments of the Belt-Purcell Supergroup and are further obscured by Mesozoic magmatism (Idaho Batholith, sensu lato). Exposures of the basement are rare but have been documented in a few regions including the Priest River Complex in northern Idaho and the Sevier fold and thrust belt just northwest of the Wyoming craton in the Great Falls tectonic zone (Foster et al. 2006). New ages and isotopic data from orthogneisses in north-central Idaho provide evidence for previously undocumented exposures of both Paleoproterozoic and Archean basement that may place important constraints on the reconstruction of Laurentia and its tectonic setting. The orthogneisses analyzed in this study (all previously mapped as deformed Cretaceous plutons) fall into two distinct age groups of 1.86 Ga and 2.67 Ga. The zircons from both the Archean and Proterozoic rocks have simple systematics. The zircons from three Archean samples have ɛHf(i) values of 2.4 ± 2.1, 3.8 ± 1.8, and 5.2 ± 3.5 (average values based on 6 individual zircon Hf analyses per sample). Zircons from the Paleoproterozoic gneisses have different but internally consistent ɛHf(i) values of -8.0 ± 0.9 and -0.6 ± 1.4. In contrast, both Hf and Nd whole rock data are highly scattered in these samples especially in the Archean samples in which ɛHf(i) varies from -25 to +21 and ɛNd(i) varies from -8 to +11. These extreme values are implausible for initial compositions and indicate open system behavior in both Lu-Hf and Sm-Nd in the whole rocks. The zircons, in contrast, appear to be closed to significant Hf mobility on the scale of the laser analyses. The data

  12. Research progress and harnessing method of soil and water loss in Pisha Sandstone region

    NASA Astrophysics Data System (ADS)

    Xiao, P. Q.; Yang, C. X.; Jing, C. R.

    2018-05-01

    Pisha Sandstone region is the most vulnerable and the most dramatic area of soil erosion, severe soil erosion on the ecological bases of China’s energy security constitutes a serious challenge. Research progress of soil erosion in pisha Sandstone region was reviewed based on the need of soil and water ecological construction in Pisha Sandstone region and harnessing the yellow river including soil erosion mechanism, soil erosion dynamic monitoring and soil erosion simulation assessments. Meanwhile, the latest progress of soil and water conservation measures was analyzed, and the existing problems and future harnessing measures of soil and water loss were discussed. This study is to explore the comprehensive management method and provide scientific theory for constructing soil and water conservation project in Pisha Sandstone region.

  13. Double-difference tomography velocity structure in Northern Oklahoma: Evidence for reduced basement velocity in the Nemaha Uplift

    NASA Astrophysics Data System (ADS)

    Stevens, N. T.; Keranen, K. M.; Lambert, C.

    2016-12-01

    Induced seismicity in northern Oklahoma presents risk for infrastructure, but also an opportunity to gain new insights to earthquake processes [Petersen et al., 2016]. Here we present a double-difference tomographic study using TomoDD [Zhang and Thurber, 2003] in northern Oklahoma utilizing records from a dense broadband network over a 1-year period, constituting a catalog of over 10,000 local seismic events. We image a shallow (depth < 4 km) high-velocity structure consistent with the Nemaha uplift [Gay, 2003a], bounded by shallow, lower-velocity regions on either side, likely sedimentary strata at this depth bounding uplifted basement. Velocities within the uplift are lower than expected in subjacent crystalline basement rock (depth > 4 km). We suggest that this low velocity anomaly stems from enhanced fracturing and/or weathering of the basement in the Nemaha uplift in northern Oklahoma. This velocity anomaly is not observed in basement off the shoulders of the structure, particularly to the southeast of the Nemaha bounding fault. Enhanced fracturing, and related increases to permeability, would ease pressure migration from injection wells linked to increased seismicity in the region, and may explain the relative absence of seismicity coincident with this structure compared to it periphery. References Gay, S. Parker, J. (2003), The Nemaha Trend-A System of Compressional Thrust-Fold, Strike-Slilp Structural Features in Kansas and Oklahoma, Part 1, Shale Shak., 9-49. Petersen, M. D., C. S. Mueller, M. P. Moschetti, S. M. Hoover, A. L. Llenos, W. L. Ellsworth, A. J. Michael, J. L. Rubinstein, A. F. McGarr, and K. S. Rukstales (2016), 2016 One-Year Seismic Hazard Forecast for the Central and Eastern United States from Induced and Natural Earthquakes, Open-File Rep., doi:10.3133/OFR20161035. Zhang, H., and C. H. Thurber (2003), Double-difference tomography: The method and its application to the Hayward Fault, California, Bull. Seismol. Soc. Am., 93(5), 1875-1889, doi

  14. Proterozoic crustal evolution of the Eucla basement, Australia: Implications for destruction of oceanic crust during emergence of Nuna

    NASA Astrophysics Data System (ADS)

    Kirkland, C. L.; Smithies, R. H.; Spaggiari, C. V.; Wingate, M. T. D.; Quentin de Gromard, R.; Clark, C.; Gardiner, N. J.; Belousova, E. A.

    2017-05-01

    The crystalline basement beneath the Cretaceous to Cenozoic Bight and Eucla Basins, in Western Australia has received comparatively little attention even though it lies on the eastern margin of one of the most mineral resource endowed regions on the planet. This basement is characterized by a complex geological evolution spanning c. 2 billion years, but paucity of outcrop and younger basin cover present a daunting challenge to understand the basement geology. In this work the composition of the unexposed Proterozoic crystalline basement to the Bight and Eucla Basins is investigated through zircon Hf isotopes and whole rock geochemistry from new drillcore samples. This region includes two geophysically defined basement entities: The Madura Province, containing: 1) c. 1478 Ma Sleeper Camp Formation, which has variable isotopic signatures including evolved values interpreted to reflect reworking of rare slivers of hyperextended Archean crust, 2) 1415-1389 Ma Haig Cave Supersuite, with mantle-like isotope values interpreted as melting of subduction-modified N-MORB source, and 3) 1181-1125 Ma Moodini Supersuite, with juvenile isotopic signatures interpreted to reflect mixed mafic lower-crustal and asthenospheric melts produced at the base of thinned crust. The Coompana Province, to the east of the Madura Province, has three major magmatic components: 1) c. 1610 Ma Toolgana Supersuite, with chemical and isotopic characteristics of primitive arc rock, 2) c. 1490 Ma Undawidgi Supersuite, with juvenile isotope values consistent with extensional processes involving asthenospheric input and 3) 1192-1140 Ma Moodini Supersuite, with strong isotopic similarity to Moodini Supersuite rocks in the Madura Province. This new isotopic and geochemical data shows that the Madura and Coompana regions together represent a huge tract of predominantly juvenile material. Magma sources recognised, include; 1) depleted mantle, producing MORB-like crust at c. 1950 Ma, but also contributing to

  15. MTR WING A, TRA604, INTERIOR. BASEMENT. DETAIL OF A19 LAB ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    MTR WING A, TRA-604, INTERIOR. BASEMENT. DETAIL OF A-19 LAB AREA ALONG SOUTH WALL. SIGN ON FLOOR DIRECTS WORKERS TO OBTAIN WHOLE BODY FRISK UPON LEAVING AREA. SIGN ON EQUIPMENT IN CENTER OF VIEW REQUESTS WORKERS TO "NOTIFY HEALTH PHYSICS BEFORE WORKING ON THIS SYSTEM." CAMERA FACING SOUTHWEST. INL NEGATIVE NO. HD46-13-2. Mike Crane, Photographer, 2/2005 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  16. APPALACHIAN FOLDS, LATERAL RAMPS, AND BASEMENT FAULTS: A MODERN ENGINEERING PROBLEM?

    USGS Publications Warehouse

    Pohn, Howard A.

    1987-01-01

    Field studies and analysis of radar data have shown that cross-strike faulting in the central and southern Appalachians has affected geologic structures at the surface. These basement faults appear to have been active through much of geologic time. Indeed, more than 45 percent of modern earthquakes occur along these narrow zones here termed 'lateral ramps. ' Because of this seismic activity, these lateral ramps are likely to be zones that are prone to slope failure. The engineer should be aware of the presence of such zones and the higher landslide potential along them.

  17. Synthesis and deposition of basement membrane proteins by primary brain capillary endothelial cells in a murine model of the blood-brain barrier.

    PubMed

    Thomsen, Maj Schneider; Birkelund, Svend; Burkhart, Annette; Stensballe, Allan; Moos, Torben

    2017-03-01

    The brain vascular basement membrane is important for both blood-brain barrier (BBB) development, stability, and barrier integrity and the contribution hereto from brain capillary endothelial cells (BCECs), pericytes, and astrocytes of the BBB is probably significant. The aim of this study was to analyse four different in vitro models of the murine BBB for expression and possible secretion of major basement membrane proteins from murine BCECs (mBCECs). mBCECs, pericytes and glial cells (mainly astrocytes and microglia) were prepared from brains of C57BL/6 mice. The mBCECs were grown as monoculture, in co-culture with pericytes or mixed glial cells, or as a triple-culture with both pericytes and mixed glial cells. The integrity of the BBB models was validated by measures of transendothelial electrical resistance (TEER) and passive permeability to mannitol. The expression of basement membrane proteins was analysed using RT-qPCR, mass spectrometry and immunocytochemistry. Co-culturing mBCECs with pericytes, mixed glial cells, or both significantly increased the TEER compared to the monoculture, and a low passive permeability was correlated with high TEER. The mBCECs expressed all major basement membrane proteins such as laminin-411, laminin-511, collagen [α1(IV)] 2 α2(IV), agrin, perlecan, and nidogen 1 and 2 in vitro. Increased expression of the laminin α5 subunit correlated with the addition of BBB-inducing factors (hydrocortisone, Ro 20-1724, and pCPT-cAMP), whereas increased expression of collagen IV α1 primarily correlated with increased levels of cAMP. In conclusion, BCECs cultured in vitro coherently form a BBB and express basement membrane proteins as a feature of maturation. Cover Image for this issue: doi: 10.1111/jnc.13789. © 2016 International Society for Neurochemistry.

  18. Shock pressure estimation in basement rocks of the Chicxulub impact crater using cathodoluminescence spectroscopy of quartz

    NASA Astrophysics Data System (ADS)

    Tomioka, N.; Tani, R.; Kayama, M.; Chang, Y.; Nishido, H.; Kaushik, D.; Rae, A.; Ferrière, L.; Gulick, S. P. S.; Morgan, J. V.

    2017-12-01

    The Chicxulub impact structure, located in the northern Yucatan Peninsula, Mexico, was drilled by the joint IODP-ICDP Expedition 364 in April-May 2016. This expedition is the first attempt to obtain materials from the topographic peak ring within the crater previously identified by seismic imaging. A continuous core was successfully recovered from the peak ring at depths between 505.7 and 1334.7 mbsf. Uplifted, fractured, and shocked granitic basement rocks forming the peak ring were found below, in the impact breccia and impact melt rock unit (747.0-1334.7 mbsf; Morgan et al. 2016). In order to constrain impact crater formation, we investigated shock pressure distribution in the peak-ring basement rocks. Thin sections of the granitic rocks were prepared at intervals of 60 m. All the samples contains shocked minerals, with quartz grains frequently showing planar deformation features (PDFs). We determined shock pressures based on the cathodoluminescence (CL) spectroscopy of quartz. The strong advantage of the CL method is its applicability to shock pressure estimation for individual grains for both quartz and diaplectic SiO2 glass with high-spatial resolution ( 1 μm) (Chang et al. 2016). CL spectra of quartz shows a blue emission band caused by shock-induced defect centers, where its intensity increases with shock pressure. A total of 108 quartz grains in ten thin sections were analyzed using a scanning electron microscope with a CL spectrometer attached (an acceleration voltage of 15 kV and a beam current of 2 nA were used). Natural quartz single crystals, which were experimentally shocked at 0-30 GPa, were used for pressure calibration. CL spectra of all the quartz grains in the basement rocks showed broad blue emission band at the wavelength range of 300-500 nm and estimated shock pressures were in the range of 15-20 GPa. The result is consistent with values obtained from PDFs analysis in quartz using the universal stage (Ferrière et al. 2017; Rae et al. 2017

  19. Thermal history of the Pan-African basement under the Jurassic Marib-Shabwa Basin, Yemen

    NASA Astrophysics Data System (ADS)

    Rice, A. Hugh N.; Schneider, David; Veeningen, Resi; Grasemann, Bernhard; Decker, Kurt

    2013-04-01

    Pan-African tectonism within the Arabian Nubian Shield in Yemen is very poorly known. New drill-cores from the Marib-Shabwa Basin (Habban oil field) from central Yemen penetrated 600 m into the pre-Jurassic crystalline basement, providing a unique opportunity to extend our understanding of Pan-African events in Yemen. The cores were obtained some 80 km NE of the exposure limit of the Al Bayda Terrane, which lies SE of Sana'a. This terrane, which has no direct correlative in the ANS further north in Saudi Arabia, comprises deformed greenschist facies acid to basic volcanic rocks later witnessing acid to basic magmatism and has been previously interpreted as a Pan-African island arc complex with a basement component. Ophiolite fragments are common, both within the terrane and at its margins (sutures). To the north lies the Abas Gneiss Terrane and to the south the Al Mahfid Gneiss Terrane; both consist of older pre-Pan-African crystalline basement rocks. Geochemistry of a red, undeformed granite from the drill core indicates an A-type composition. LA-ICPMS U-Pb analysis of granite zircons gave two concordant age populations: 628.3 ± 3.1 Ma (large & small zircons) and 604.9 ± 2.0 Ma (intermediate sized zircons). The former age is interpreted as the time of crystallization, within the range of other A-type Younger Granites in the ANS, and the latter age as constraining lower temperature dissolution-reprecipitation of zircon, due to hydrothermal fluids or melt remobilization. Nd Tdm model ages for two granite samples from the drill core both gave ages of 1.24 Ga, within the range of the Al Bayda Terrane (1.2-2.5 Ga) and outside the range of the adjacent Palaeoproterozoic gneissic terranes (1.7-2.3 Ga, Abas Gneiss Terrane; 1.8-3.0 Ga, Al Mahfid Gneiss Terrane). Thus it seems certain that the Al Bayda Terrane extends at least 80 km to the NE of its present surface exposure. Rb-Sr biotite ages from the granite indicate closure through ~300°C at 593 Ma, indicating fast

  20. Harnessing dendritic cells in inflammatory skin diseases.

    PubMed

    Chu, Chung-Ching; Di Meglio, Paola; Nestle, Frank O

    2011-02-01

    The skin immune system harbors a complex network of dendritic cells (DCs). Recent studies highlight a diverse functional specialization of skin DC subsets. In addition to generating cellular and humoral immunity against pathogens, skin DCs are involved in tolerogenic mechanisms to ensure the maintenance of immune homeostasis, as well as in pathogenesis of chronic inflammation in the skin when excessive immune responses are initiated and unrestrained. Harnessing DCs by directly targeting DC-derived molecules or selectively modulate DC subsets is a convincing strategy to tackle inflammatory skin diseases. In this review we discuss recent advances underlining the functional specialization of skin DCs and discuss the potential implication for future DC-based therapeutic strategies. Copyright © 2011 Elsevier Ltd. All rights reserved.

  1. MODELING H-ARS USING HEMATOLOGICAL PARAMETERS: A COMPARISON BETWEEN THE NON-HUMAN PRIMATE AND MINIPIG.

    PubMed

    Bolduc, David L; Bünger, Rolf; Moroni, Maria; Blakely, William F

    2016-12-01

    Multiple hematological biomarkers (i.e. complete blood counts and serum chemistry parameters) were used in a multivariate linear-regression fit to create predictive algorithms for estimating the severity of hematopoietic acute radiation syndrome (H-ARS) using two different species (i.e. Göttingen Minipig and non-human primate (NHP) (Macacca mulatta)). Biomarker data were analyzed prior to irradiation and between 1-60 days (minipig) and 1-30 days (NHP) after irradiation exposures of 1.6-3.5 Gy (minipig) and 6.5 Gy (NHP) 60 Co gamma ray doses at 0.5-0.6 Gy min -1 and 0.4 Gy min -1 , respectively. Fitted radiation risk and injury categorization (RRIC) values and RRIC prediction percent accuracies were compared between the two models. Both models estimated H-ARS severity with over 80% overall predictive power and with receiver operating characteristic curve area values of 0.884 and 0.825. These results based on two animal radiation models support the concept for the use of a hematopoietic-based algorithm for predicting the risk of H-ARS in humans. Published by Oxford University Press 2016. This work is written by (a) US Government employee(s) and is in the public domain in the US.

  2. Evidence for synchronous thin-skinned and basement deformation in the Cordilleran fold-thrust belt: the Tendoy Mountains, southwestern Montana

    NASA Astrophysics Data System (ADS)

    McDowell, Robin John

    1997-01-01

    The Tendoy Mountains contain the easternmost thin-skinned thrust sheets in the Cordilleran fold-thrust belt of southwestern Montana, and are in the zone of tectonic overlap between the Rocky Mountain foreland and the Cordilleran fold-thrust belt. The three frontal thrust sheets of the Tendoy Mountains are from north to south, the Armstead, McKenzie, and Tendoy sheets. Near the southeastern terminus of the Tendoy thrust sheet is a lateral ramp in which the Tendoy thrust climbs along strike from the Upper Mississippian Lombard Limestone to lower Cretaceous rocks. This ramp coincides with the southeastern side of the Paleozoic Snowcrest trough and projection of the range-flanking basement thrust of the Blacktail-Snowcrest uplift, suggesting either basement or stratigraphic control on location of the lateral ramp. Axes of major folds on the southern part of the Tendoy thrust sheet are parallel to the direction of thrust transport and to the trend of the Snowcrest Range. They are a result of: (1) Pre-thrust folding above basement faults; (2) Passive transportation of the folds from a down-plunge position; (3) Minor reactivation of basement faults; and (4) Emplacement of blind, sub-Tendoy, thin-skinned thrust faults. The Tendoy sheet also contains a major out-of-sequence thrust fault that formed in thick Upper Mississippian shales and created large, overturned, foreland-verging folds in Upper Mississippian to Triassic rocks. The out-of-sequence fault can be identified where stratigraphic section is omitted, and by a stratigraphic separation diagram that shows it cutting down section in the direction of transport. The prominent lateral ramp at the southern terminus of the Tendoy thrust sheet is a result of fault propagation through strata folded over the edge of the Blacktail-Snowcrest uplift.

  3. Flexural subsidence and basement tectonics of the Cretaceous Western Interior basin, United States

    NASA Astrophysics Data System (ADS)

    Pang, Ming; Nummedal, Dag

    1995-02-01

    The flexural subsidence history recorded in Cenomanian to early Campanian (97 to 80 Ma) strata in the Cretaceous U.S. Western Interior basin was studied with two-dimensional flexural backstripping techniques. Results indicate that the flexural subsidence resulting from thrust loading was superimposed on epeirogenic subsidence in the foreland basin. The flexural component exhibits significant spatial and temporal variations along both the strike and dip relative to the Sevier thrust belt. The greatest cumulative subsidence occurred in southwestern Wyoming and northern Utah. Concurrent subsidence in northwestern Montana and southern Utah was insignificant. Temporal trends in subsidence also show a distinct regional pattern. From the Cenomanian to late Turonian (97 to 90 Ma), subsidence rates were high in Utah and much lower in Wyoming and Montana. In contrast, during the Coniacian and Santonian (90 to 85 Ma) subsidence accelerated rapidly in Wyoming, increased slightly in Montana, and decreased in Utah. We suggest that these spatially and temporally varying subsidence patterns reflect the interplay of several geodynamic factors, including: (1) temporal and spatial variation in emplacement of the thrust loads, (2) segmentation of the basement into adjacent blocks with different rheological properties, (3) reactivation of basement fault trends, and (4) regional dynamic topographic effects.

  4. Mapping the Sea Floor of the Historic Area Remediation Site (HARS) Offshore of New York City

    USGS Publications Warehouse

    Butman, Bradford

    2002-01-01

    The area offshore of New York City has been used for the disposal of dredged material for over a century. The area has also been used for the disposal of other materials such as acid waste, industrial waste, municipal sewage sludge, cellar dirt, and wood. Between 1976 and 1995, the New York Bight Dredged Material Disposal Site, also known as the Mud Dump Site (MDS), received on average about 6 million cubic yards of dredged material annually. In September 1997 the MDS was closed as a disposal site, and it and the surrounding area were designated as the Historic Area Remediation Site (HARS). The sea floor of the HARS, approximately 9 square nautical miles in area, currently is being remediated by placing a minimum 1-m-thick cap of clean dredged material on top of the surficial sediments that are contaminated from previous disposal of dredged and other materials. The U.S. Geological Survey (USGS) is working cooperatively with the U.S. Army Corps of Engineers (USACE) to map the sea floor geology of the HARS and changes in the characteristics of the surficial sediments over time.

  5. Image-based modelling of lateral magma flow: the Basement Sill, Antarctica

    PubMed Central

    Mirhadizadeh, Seyed

    2017-01-01

    The McMurdo Dry Valleys magmatic system, Antarctica, provides a world-class example of pervasive lateral magma flow on a continental scale. The lowermost intrusion (Basement Sill) offers detailed sections through the now frozen particle microstructure of a congested magma slurry. We simulated the flow regime in two and three dimensions using numerical models built on a finite-element mesh derived from field data. The model captures the flow behaviour of the Basement Sill magma over a viscosity range of 1–104 Pa s where the higher end (greater than or equal to 102 Pa s) corresponds to a magmatic slurry with crystal fractions varying between 30 and 70%. A novel feature of the model is the discovery of transient, low viscosity (less than or equal to 50 Pa s) high Reynolds number eddies formed along undulating contacts at the floor and roof of the intrusion. Numerical tracing of particle orbits implies crystals trapped in eddies segregate according to their mass density. Recovered shear strain rates (10−3–10−5 s−1) at viscosities equating to high particle concentrations (around more than 40%) in the Sill interior point to shear-thinning as an explanation for some types of magmatic layering there. Model transport rates for the Sill magmas imply a maximum emplacement time of ca 105 years, consistent with geochemical evidence for long-range lateral flow. It is a theoretically possibility that fast-flowing magma on a continental scale will be susceptible to planetary-scale rotational forces. PMID:28573002

  6. Image-based modelling of lateral magma flow: the Basement Sill, Antarctica.

    PubMed

    Petford, Nick; Mirhadizadeh, Seyed

    2017-05-01

    The McMurdo Dry Valleys magmatic system, Antarctica, provides a world-class example of pervasive lateral magma flow on a continental scale. The lowermost intrusion (Basement Sill) offers detailed sections through the now frozen particle microstructure of a congested magma slurry. We simulated the flow regime in two and three dimensions using numerical models built on a finite-element mesh derived from field data. The model captures the flow behaviour of the Basement Sill magma over a viscosity range of 1-10 4  Pa s where the higher end (greater than or equal to 10 2  Pa s) corresponds to a magmatic slurry with crystal fractions varying between 30 and 70%. A novel feature of the model is the discovery of transient, low viscosity (less than or equal to 50 Pa s) high Reynolds number eddies formed along undulating contacts at the floor and roof of the intrusion. Numerical tracing of particle orbits implies crystals trapped in eddies segregate according to their mass density. Recovered shear strain rates (10 -3 -10 -5  s -1 ) at viscosities equating to high particle concentrations (around more than 40%) in the Sill interior point to shear-thinning as an explanation for some types of magmatic layering there. Model transport rates for the Sill magmas imply a maximum emplacement time of ca 10 5 years, consistent with geochemical evidence for long-range lateral flow. It is a theoretically possibility that fast-flowing magma on a continental scale will be susceptible to planetary-scale rotational forces.

  7. An Overlapping Case of Alport Syndrome and Thin Basement Membrane Disease.

    PubMed

    Alganabi, Mashriq; Eter, Ahmad

    2016-10-01

    We report a case of a 48-year-old male who presented with hematuria of at least 10 years, and has a daughter with hematuria as well. The patient has a history of degenerative hearing loss, decreased vision and cataract formation, but no diabetes, hypertension or proteinuria. A full serology and urology workup was negative for any abnormality. A kidney biopsy for the patient revealed a diagnosis of Alport syndrome but was unable to rule out thin basement membrane disease. The biopsy was inconclusive in making the diagnosis but the patient's clinical presentation led to the diagnosis of Alport syndrome. The patient's 10-year-old daughter also has hematuria with no clear etiology but now can subsequently be anticipatorily managed for Alport syndrome progression. Due to the rarity of the disease, diagnosis is often missed or delayed by primary care providers especially when no associated proteinuria has yet developed. This can lead to confusion and misdiagnosis with thin basement membrane disease, a generally benign hematuria without kidney failure progression. Additionally, biopsy can be inconclusive in these patients, relying on the physician's history and physical examination findings to diagnose. It is important to appropriately diagnose Alport syndrome not only to manage the patient's rate of kidney failure progression but also allow for a higher degree of suspicion, screening and intervention in the patient's family members. Both the inconclusive nature of kidney biopsies and the usefulness of diagnosis for family member screening are often overlooked in medical literature but are explored in this case.

  8. An Overlapping Case of Alport Syndrome and Thin Basement Membrane Disease

    PubMed Central

    Alganabi, Mashriq; Eter, Ahmad

    2016-01-01

    We report a case of a 48-year-old male who presented with hematuria of at least 10 years, and has a daughter with hematuria as well. The patient has a history of degenerative hearing loss, decreased vision and cataract formation, but no diabetes, hypertension or proteinuria. A full serology and urology workup was negative for any abnormality. A kidney biopsy for the patient revealed a diagnosis of Alport syndrome but was unable to rule out thin basement membrane disease. The biopsy was inconclusive in making the diagnosis but the patient’s clinical presentation led to the diagnosis of Alport syndrome. The patient’s 10-year-old daughter also has hematuria with no clear etiology but now can subsequently be anticipatorily managed for Alport syndrome progression. Due to the rarity of the disease, diagnosis is often missed or delayed by primary care providers especially when no associated proteinuria has yet developed. This can lead to confusion and misdiagnosis with thin basement membrane disease, a generally benign hematuria without kidney failure progression. Additionally, biopsy can be inconclusive in these patients, relying on the physician’s history and physical examination findings to diagnose. It is important to appropriately diagnose Alport syndrome not only to manage the patient’s rate of kidney failure progression but also allow for a higher degree of suspicion, screening and intervention in the patient’s family members. Both the inconclusive nature of kidney biopsies and the usefulness of diagnosis for family member screening are often overlooked in medical literature but are explored in this case. PMID:27635185

  9. MTR WING, TRA604, INTERIOR. BASEMENT. INTERIOR VIEW FROM SAME LOCATION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    MTR WING, TRA-604, INTERIOR. BASEMENT. INTERIOR VIEW FROM SAME LOCATION IN WEST CORRIDOR AS PHOTO ID-33-G-42 BUT CAMERA FACES SOUTH. SIGN ON DOOR FOR "PIPE TUNNEL" WARNS OF RADIOLOGICAL AND ASBESTOS HAZARDS. DOOR HAS METAL HASPS. SIGN ON OVERHEAD WASTE HEAT RECOVERY PIPES SAYS THEY CONTAIN "ASBESTOS FREE INSULATION." FIRE DOOR AT LEFT LEADS TO STAIRWAY TO FIRST FLOOR. DOOR AT RIGHT LEADS TO ROOM WHICH ONCE CONTAINED MTR LIBRARY. INL NEGATIVE NO. HD46-13-4. Mike Crane, Photographer, 2/2005 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  10. PBF Reactor Building (PER620) basement. Workers wearing protective gear work ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PBF Reactor Building (PER-620) basement. Workers wearing protective gear work inside cubicle 13 on the fission product detection system. Man on left is atop shielded box shown in previous photo. Posture of second man illustrates waist-high height of shielding box. His hand rests on the access panel, which has been filled with lead bricks and which has been slid shut to enclose detection instruments within box. Photographer: John Capek. Date: January 24, 1983. INEEL negative no. 83-41-3-5 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

  11. Basement domain map of the conterminous United States and Alaska

    USGS Publications Warehouse

    Lund, Karen; Box, Stephen E.; Holm-Denoma, Christopher S.; San Juan, Carma A.; Blakely, Richard J.; Saltus, Richard W.; Anderson, Eric D.; DeWitt, Ed

    2015-01-01

    The tectonic settings for crustal types represented in the basement domains are subdivided into constituent geologic environments and the types of primary metals endowments and deposits in them are documented. The compositions, architecture, and original metals endowments are potentially important to assessments of primary mineral deposits and to the residence and recycling of metals in the crust of the United States portion of the North American continent. The databases can be configured to demonstrate the construction of the United States through time, to identify specific types of crust, or to identify domains potentially containing metal endowments of specific genetic types or endowed with specific metals. The databases can also be configured to illustrate other purposes chosen by users.

  12. Did the Basement-Involved Main Caucasus Thrust Form during the Cenozoic Arabia-Eurasia Collision?

    NASA Astrophysics Data System (ADS)

    Vasey, D. A.; Cowgill, E.; Niemi, N. A.; Godoladze, T.; Javakhishvili, Z.; Skhirtladze, I.; Boichenko, G.

    2017-12-01

    The Greater Caucasus Mountains lie between the Black and Caspian Seas at the northern margin of the active Arabia-Eurasia collision zone. The north-dipping Main Caucasus Thrust (MCT) is commonly assumed to be a first-order structure within the range that places Paleozoic crystalline basement to the north over metasedimentary cover of inferred Mesozoic age to the south. Although most workers assume this juxtaposition occurred during Cenozoic growth of the range, the timing of ductile (quartz-plastic) shearing along the MCT remains to be established. Here, we present data to discriminate between two competing models of quartz-plastic deformation along the proposed MCT location at the basement-cover contact. In the first model, quartz-plastic deformation occurred during the Cenozoic Arabia-Eurasia collision, whereas in the second, this deformation took place during an older orogenic event, such as the Paleozoic Variscan orogeny. To test these models, we are combining field observations, microstructural investigations, and thermochronologic analyses on two 10 km-long traverses in the Republic of Georgia, separated by 200 km along strike, across the MCT. Our fieldwork and microstructural analyses along the basement-cover contact document north-dipping zones of high strain that are 100 m thick and show quartz-plastic deformation, top-to-the-south shear sense, and greenschist-facies metamorphism. Zircon (U-Th)/He (ZHe) analyses along the eastern traverse near Stepantsminda yielded latest Miocene ( 7-8 Ma) ages in both the MCT shear zone and 150 m structurally above the MCT. In contrast, along the western traverse near Nakra, a sample 300 m structurally below the MCT yielded an early Oligocene ( 31 Ma) ZHe age. These data require Cenozoic exhumation from temperatures >180° and are compatible with recent ductile shear along the MCT. However, results from biotite and muscovite 40Ar/39Ar analyses in progress are needed to confirm this hypothesis. The MCT appears to have

  13. Harnessing Sparse and Low-Dimensional Structures for Robust Clustering of Imagery Data

    ERIC Educational Resources Information Center

    Rao, Shankar Ramamohan

    2009-01-01

    We propose a robust framework for clustering data. In practice, data obtained from real measurement devices can be incomplete, corrupted by gross errors, or not correspond to any assumed model. We show that, by properly harnessing the intrinsic low-dimensional structure of the data, these kinds of practical problems can be dealt with in a uniform…

  14. The Facebook-in-Action: Challenging, Harnessing and Enhancing Students Class Assignments and Projects

    ERIC Educational Resources Information Center

    Saifudin, Adam Mohd; Yacob, Aizan; Saad, Rohaizah

    2016-01-01

    Issues of universities students harnessing and capitalizing the usage of Facebook for their own learning capabilities and effective thinking is always the focus of education scholars, in assessing the quality class assignments and projects produced by them. Therefore, Facebook is now becoming unbearable influence since the internet activation in…

  15. The First Evidence of the Precambrian Basement in the Fore Range Zone of the Great Caucasus.

    NASA Astrophysics Data System (ADS)

    Latyshev, A.; Kamzolkin, V.; Vidjapin, Y.; Somin, M.; Ivanov, S.

    2017-12-01

    Within the Great Caucasus fold-thrust belt, the Fore Range zone has the most complicated structure, and the highest degree of metamorphism was found there. This zone consists of several salients with the different composition and the structural and metamorphic evolution. The largest Blyb salient includes the metamorphic basement covered by the pack of thrusts. According to the recent isotopic data the upper levels of the Blyb metamorphic complex (BMC) are supposed to be Middle-Paleozoic (Somin, 2011). We studied zircons from the granitic intrusions located in the metamorphic rocks of the BMC. The U-Pb dating (SHRIMP II, VSEGEI, Russia) of zircons from the large Balkan metadiorite massif yielded the ages of 549±7,4, 574,1±6,7, and 567,9±6,9 Ma. All studied zircons show the high Th/U ratios and likely have the magmatic origin. This data is the first confirmation of the presence of the Precambrian basement and Vendian magmatic activity in the Fore Range zone. Zircons from the Unnamed granodiorite massif from the south of the Blyb salient yielded the age of 319±3.8 Ma (the Early Carboniferous). This fact taken together with the low grade of metamorphism in this intrusion reveals the Late Paleozoic magmatic event in the Fore Range zone. We also suggest that the Precambrian basement of the BMC, including the Balkan intrusion, is covered by so-called Armovsky nappe. This is confirmed by the field data, Middle-Paleozoic U-Pb ages and the higher degree of metamorphism of the Armovsky gneisses and schists. Thus, the BMC is not uniform but includes the blocks of the different age and metamorphic grades. Finally, we measured the anisotropy of magnetic susceptibility (AMS) of the Balkan metadiorites. The axes of AMS ellipsoid fix the conditions of the north-east compression, as well as the strain field reconstructed from the macrostructures orientation, which corresponds to the thrusts propagation. Therefore, the emplacement of the Balkan massif happened before the thrust

  16. Petrographic and geochemical comparisons between the lower crystalline basement-derived section and the granite megablock and amphibolite megablock of the Eyreville-B core, Chesapeake Bay impact structure

    USGS Publications Warehouse

    Townsend, Gabrielle N.; Gibson, Roger L.; Horton, J. Wright; Reimold, Wolf Uwe; Schmitt, Ralf T.; Bartosova, Katerina

    2009-01-01

    The Eyreville B core from the Chesapeake Bay impact structure, Virginia, USA, contains a lower basement-derived section (1551.19 m to 1766.32 m deep) and two megablocks of dominantly (1) amphibolite (1376.38 m to 1389.35 m deep) and (2) granite (1095.74 m to 1371.11 m deep), which are separated by an impactite succession. Metasedimentary rocks (muscovite-quartz-plagioclase-biotite-graphite ± fibrolite ± garnet ± tourmaline ± pyrite ± rutile ± pyrrhotite mica schist, hornblende-plagioclase-epidote-biotite-K-feldspar-quartz-titanite-calcite amphibolite, and vesuvianite-plagioclase-quartz-epidote calc-silicate rock) are dominant in the upper part of the lower basement-derived section, and they are intruded by pegmatitic to coarse-grained granite (K-feldspar-plagioclase-quartz-muscovite ± biotite ± garnet) that increases in volume proportion downward. The granite megablock contains both gneissic and weakly or nonfoliated biotite granite varieties (K-feldspar-quartz-plagioclase-biotite ± muscovite ± pyrite), with small schist xenoliths consisting of biotite-plagioclase-quartz ± epidote ± amphibole. The lower basement-derived section and both megablocks exhibit similar middle- to upper-amphibolite-facies metamorphic grades that suggest they might represent parts of a single terrane. However, the mica schists in the lower basement-derived sequence and in the megablock xenoliths show differences in both mineralogy and whole-rock chemistry that suggest a more mafic source for the xenoliths. Similarly, the mineralogy of the amphibolite in the lower basement-derived section and its association with calc-silicate rock suggest a sedimentary protolith, whereas the bulk-rock and mineral chemistry of the megablock amphibolite indicate an igneous protolith. The lower basement-derived granite also shows bulk chemical and mineralogical differences from the megablock gneissic and biotite granites.

  17. Experimental approach to domino-style basement fault systems with evaporites during extension and subsequent inversion

    NASA Astrophysics Data System (ADS)

    Ferrer, Oriol; McClay, Ken

    2017-04-01

    Salt is mechanically weaker than other sedimentary rocks in rift basins. During extension it commonly acts as a strain localizer, decoupling supra- and sub-salt deformation. In this scenario the movement of the subsalt faults combined with the salt migration commonly constraint the development of syncline basins. The shape of these synclines is basically controlled by the thickness and strength of the overlying salt section, as well as by the shapes of the extensional faults, and the magnitudes and slip rates along the faults. The inherited extensional structure, and particularly the continuity of the salt section, plays a key role if the rift basin is subsequently inverted. This research utilizes scaled physical models to analyse the interplay between subsalt structures and suprasalt units during both extension and inversion in domino-style basement fault systems. The experimental program includes twelve analogue models to analyze how the thickness and stratigraphy of the salt unit as well as the thickness of the pre-extensional cover constraint the structural style during extension and subsequent inversion. Different models with the same setup have been used to examine the kinematic evolution. Model kinematics was documented and analyzed combining high-resolution photographs and sub-millimeter resolution scanners. The vertical sections carried out at the end of the experiments have been used to characterize the variations of the structures along strike using new methodologies (3D voxel models in image processing software and 3D seismic). The experimental results show that after extension, rift systems with salt affected by domino-style basement faults don't show the classical growth stratal wedges. In this case synclinal basins develop above the salt on the hangingwall of the basement faults. The evolution of supra- and subsalt deformation is initially decoupled by the salt layer. Salt migrates from the main depocenters towards the edges of the basin constraining

  18. Innovation in the Harnessing and Transfer of Technology: The Gran Mariscal de Ayacucho Foundation

    ERIC Educational Resources Information Center

    Lerner de Almea, Ruth

    1977-01-01

    Discusses the background, organization, success, problems, and functions of the Gran Mariscal de Ayacucho Foundation, Caracas, Venezuela, for producing human resources for the harnessing of scientific technology. The fellowship program supports study by students both at home and abroad. (SL)

  19. ETR BUILDING, TRA642, INTERIOR. BASEMENT. CUBICLE SHOWN IN ID33G101, ANOTHER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ETR BUILDING, TRA-642, INTERIOR. BASEMENT. CUBICLE SHOWN IN ID-33-G-101, ANOTHER VIEW. PERSONNEL DOORWAY INTO CHAMBER IDENTIFIES SODIUM HAZARD AND POSSIBILITY OF INERT GAS. LIQUID SODIUM COOLANT WAS USED IN A SPECIAL ETR LOOP ADAPTED FOR IT IN 1972. INL NEGATIVE NO. HD24-3-2. Mike Crane, Photographer, 11/2000 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  20. LA-ICP-MS zircon U-Pb and muscovite K-Ar ages of basement rocks from the south arm of Sulawesi, Indonesia

    NASA Astrophysics Data System (ADS)

    Jaya, Asri; Nishikawa, Osamu; Hayasaka, Yasutaka

    2017-11-01

    The zircon U-Pb and muscovite K-Ar age from the Bantimala, Barru and Biru basement complexes in the South Arm of Sulawesi, Indonesia provide new information regarding the timing of magmatism, metamorphism and sedimentation in this region and have implications for the origin and evolution of the study area. The study area is at the juncture between the southeast margin of Sundaland and Bird's Head-Australia. The age of both the zircon U-Pb of detrital materials in the Bantimala Complex and the muscovite K-Ar of amphibolite in the Biru Complex fall in the Late Early Cretaceous (between 109 and 115 Ma), which is a similar age range to previous data for both the sedimentary and metamorphic rocks. The youngest detrital zircon in the schist samples from the Barru Complex fall into the Triassic in age (between 243 and 247 Ma). These age data indicate that the protolith of all three basement complexes were involved in the subduction system and metamorphosed in the late Early Cretaceous, but there are several differences in their deposition environment under and out of the influence of the late Early Cretaceous magmatism in the Bantimala and Barru Complexes, respectively. Felsic igneous activities are confirmed in the Late Cretaceous and the Eocene by the zircon U-Pb age of igneous rocks intruding or included as detrital fragments in three basement complexes. These dates are similar to those reported from the Meratus Complex of South Kalimantan. The detrital zircon age distributions of the basement rocks in the South Arm of Sulawesi display predominant Mesozoic (Cretaceous and Triassic) and Paleozoic populations with a small population of Proterozoic ages supporting the hypothesis that the West Sulawesi block originated from the region of the circum Bird's Head-Australian, namely the Inner Banda block. The absence of Jurassic zircon age population in the South Arm of Sulawesi suggests the division of the South Arm of Sulawesi from the Inner Banda block in early stage of

  1. Expert guidelines for the management of Alport syndrome and thin basement membrane nephropathy.

    PubMed

    Savige, Judy; Gregory, Martin; Gross, Oliver; Kashtan, Clifford; Ding, Jie; Flinter, Frances

    2013-02-01

    Few prospective, randomized controlled clinical trials address the diagnosis and management of patients with Alport syndrome or thin basement membrane nephropathy. Adult and pediatric nephrologists and geneticists from four continents whose clinical practice focuses on these conditions have developed the following guidelines. The 18 recommendations are based on Level D (Expert opinion without explicit critical appraisal, or based on physiology, bench research, or first principles-National Health Service category) or Level III (Opinions of respected authorities, based on clinical experience, descriptive studies, or reports of expert committees-U.S. Preventive Services Task Force) evidence. The recommendations include the use of genetic testing as the gold standard for the diagnosis of Alport syndrome and the demonstration of its mode of inheritance; the need to identify and follow all affected members of a family with X-linked Alport syndrome, including most mothers of affected males; the treatment of males with X-linked Alport syndrome and individuals with autosomal recessive disease with renin-angiotensin system blockade, possibly even before the onset of proteinuria; discouraging the affected mothers of males with X-linked Alport syndrome from renal donation because of their own risk of kidney failure; and consideration of genetic testing to exclude X-linked Alport syndrome in some individuals with thin basement membrane nephropathy. The authors recognize that as evidence emerges, including data from patient registries, these guidelines will evolve further.

  2. Geological Structure of the Basement of Western and Eastern Parts of the West-Siberian Plain

    ERIC Educational Resources Information Center

    Ivanov, Kirill S.; Erokhin, Yuriy V.; Ponomarev, Vladimir S.; Pogromskaya, Olga E.; Berzin, Stepan V.

    2016-01-01

    The U-Pb dating (SHRIMP-II on zircon) was obtained for the first time from the basement of the West Siberian Plain in the Western half of the region. It is established that a large part of the protolith of the metamorphic depth in the Shaim-Kuznetsov meganticlinorium contained sedimentary late- and middle-Devonian rocks (395-358 million years).…

  3. Study of the relationship between mononuclear inflammatory infiltrate and Ki-67 and basement membrane and extracellular matrix protein expression in radicular cysts.

    PubMed

    Mourão, R V C; Júnior, E C Pinheiro; Barros Silva, P G; Turatti, E; Mota, M R L; Alves, A P N N

    2016-05-01

    To evaluate the relationship between mononuclear inflammatory infiltrate and the expression of a proliferative immunomarker (Ki-67) as well as to evaluate basement membrane and extracellular matrix proteins (laminin and collagen type IV) in radicular cysts and dentigerous cysts (DC). Immunohistochemical analyses were performed in heavily inflamed radicular cysts (HIRC), slightly inflamed radicular cysts (SIRC) and DC (n = 20) using Ki-67 (Dako(®) , 1 : 50), anticollagen type IV (DBS(®) , 1 : 40) and antilaminin (DBS(®) , 1 : 20). The data were analysed using anova/Tukey's test (Ki-67) and Kruskal-Wallis/Dunn's test (collagen type IV and laminin) (P < 0.05). The immunoexpression of Ki-67 was significantly greater in the SIRC group compared with the HIRC and DC (P = 0.0040). Likewise, the immunoexpression of collagen type IV in the basement membrane of the SIRC group was significantly more continuous (P = 0.0475) than in the HIRC group. DC had significantly less collagen type IV in extracellular matrix immunoexpression than HIRC and SIRC (P = 0.0246). Laminin was absent in the basement membrane in the SIRC and DC groups, and the extracellular matrix of the HIRC was weak and punctate. The presence of inflammatory factors in the radicular cyst wall modified the expression of proliferation factors in the epithelial lining and the expression of collagen type IV and laminin in the basement membrane, but did not modify extracellular matrix behaviour in radicular cysts. © 2015 International Endodontic Journal. Published by John Wiley & Sons Ltd.

  4. Inheritance, Variscan tectonometamorphic evolution and Permian to Mesozoic rejuvenations in the metamorphic basement complexes of the Romanian Carpathians revealed by monazite microprobe geochronology

    NASA Astrophysics Data System (ADS)

    Săbău, Gavril; Negulescu, Elena

    2014-05-01

    Monazite U-Th-Pb chemical dating reaches an acceptable compromise between precision and accuracy on one side, and spatial resolution and textural constraints on the other side. Thus it has a powerful potential in testing the coherence of individual metamorphic basement units, and enabling correlations among them. Yet, sensitivity and specificity issues in monazite response to thermotectonic events, especially in the case of superposed effects, remain still unclear. Monazite dating at informative to detailed scale in the main metamorphic basement units of the Carpathians resulted in complex age spectra. In the main, the spectra are dominated by the most pervasive thermal and structural overprint, as checked against independent geochronological data. Post-peak age resetting is mostly present, but statistically subordinate. Resetting in case of superposed events is correlated with the degree of textural and paragenetic overprinting, inheritances being always indicated by more or less well-defined age clusters. The lack of relict ages correlating with prograde structural and porphyroblast zonation patterns is indicative for juvenile formations. Age data distribution in the Carpathians allowed distinction of pre-Variscan events, syn-metamorphic Variscan tectonic stacking of juvenile and reworked basement, post-Variscan differential tectonic uplift, as well as prograde metamorphic units ranging down to Upper Cretaceous ages. In the South Carpathians, the Alpine Danubian domain consists of several Variscan and Alpine thrust sheets containing a metamorphic complex dominated by Upper Proterozoic to Lower Cambrian metamorphic and magmatic ages (Lainici-Păiuş), and several complexes with metamorphic overprints ranging from Carboniferous to Lower Permian. Any correlation among these units, as well as geotectonic models placing a Lower Paleozoic oceanic domain between pre-existing Lainici-Păiuş and Drăgşan terranes are precluded by the age data. Other basement of the

  5. 3D gravity inversion and uncertainty assessment of basement relief via Particle Swarm Optimization

    NASA Astrophysics Data System (ADS)

    Pallero, J. L. G.; Fernández-Martínez, J. L.; Bonvalot, S.; Fudym, O.

    2017-04-01

    Nonlinear gravity inversion in sedimentary basins is a classical problem in applied geophysics. Although a 2D approximation is widely used, 3D models have been also proposed to better take into account the basin geometry. A common nonlinear approach to this 3D problem consists in modeling the basin as a set of right rectangular prisms with prescribed density contrast, whose depths are the unknowns. Then, the problem is iteratively solved via local optimization techniques from an initial model computed using some simplifications or being estimated using prior geophysical models. Nevertheless, this kind of approach is highly dependent on the prior information that is used, and lacks from a correct solution appraisal (nonlinear uncertainty analysis). In this paper, we use the family of global Particle Swarm Optimization (PSO) optimizers for the 3D gravity inversion and model appraisal of the solution that is adopted for basement relief estimation in sedimentary basins. Synthetic and real cases are illustrated, showing that robust results are obtained. Therefore, PSO seems to be a very good alternative for 3D gravity inversion and uncertainty assessment of basement relief when used in a sampling while optimizing approach. That way important geological questions can be answered probabilistically in order to perform risk assessment in the decisions that are made.

  6. Geophysical evaluation of groundwater potential in part of southwestern Basement Complex terrain of Nigeria

    NASA Astrophysics Data System (ADS)

    Bayewu, Olateju O.; Oloruntola, Moroof O.; Mosuro, Ganiyu O.; Laniyan, Temitope A.; Ariyo, Stephen O.; Fatoba, Julius O.

    2017-12-01

    The geophysical assessment of groundwater in Awa-Ilaporu, near Ago Iwoye southwestern Nigeria was carried out with the aim of delineating probable areas of high groundwater potential. The area falls within the Crystalline Basement Complex of southwestern Nigeria which is predominantly underlain by banded gneiss, granite gneiss and pegmatite. The geophysical investigation involves the very low frequency electromagnetic (VLF-EM) and Vertical Electrical Sounding (VES) methods. The VLF-EM survey was at 10 m interval along eight traverses ranging between 290 and 700 m in length using ABEM WADI VLF-EM unit. The VLF-EM survey was used to delineate areas with conductive/fractured zones. Twenty-three VES surveys were carried out with the use of Campus Ohmega resistivity meter at different location and at locations areas delineated as high conductive areas by VLF-EM survey. The result of VLF-EM survey along its traverse was used in delineating high conductive/fractured zones, it is, however, in agreement with the delineation of the VES survey. The VES results showed 3-4 geoelectric layers inferred as sandy topsoil, sandy clay, clayey and fractured/fresh basement. The combination of these two methods, therefore, helped in resolving the prospecting location for the groundwater yield in the study area.

  7. Petrographic and geochemical comparisons between the lower crystalline basement-derived section and the granite megablock and amphibolite megablock of the Eyreville B core, Chesapeake Bay impact structure, USA

    USGS Publications Warehouse

    Townsend, G.N.; Gibson, R.L.; Horton, J. Wright; Reimold, W.U.; Schmitt, R.T.; Bartosova, K.

    2009-01-01

    The Eyreville B core from the Chesapeake Bay impact structure, Virginia, USA, contains a lower basement-derived section (1551.19 m to 1766.32 m deep) and two megablocks of dominantly (1) amphibolite (1376.38 m to 1389.35 m deep) and (2) granite (1095.74 m to 1371.11 m deep), which are separated by an impactite succession. Metasedimentary rocks (muscovite-quartz-plagioclase-biotite-graphite ?? fibrolite ?? garnet ?? tourmaline ?? pyrite ?? rutile ?? pyrrhotite mica schist, hornblende-plagioclase-epidote-biotite- K-feldspar-quartz-titanite-calcite amphibolite, and vesuvianite-plagioclase- quartz-epidote calc-silicate rock) are dominant in the upper part of the lower basement-derived section, and they are intruded by pegmatitic to coarse-grained granite (K-feldspar-plagioclase-quartz-muscovite ?? biotite ?? garnet) that increases in volume proportion downward. The granite megablock contains both gneissic and weakly or nonfoliated biotite granite varieties (K-feldspar-quartz-plagioclase-biotite ?? muscovite ?? pyrite), with small schist xenoliths consisting of biotite-plagioclase-quartz ?? epidote ?? amphibole. The lower basement-derived section and both megablocks exhibit similar middleto upper-amphibolite-facies metamorphic grades that suggest they might represent parts of a single terrane. However, the mica schists in the lower basement-derived sequence and in the megablock xenoliths show differences in both mineralogy and whole-rock chemistry that suggest a more mafi c source for the xenoliths. Similarly, the mineralogy of the amphibolite in the lower basement-derived section and its association with calc-silicate rock suggest a sedimentary protolith, whereas the bulk-rock and mineral chemistry of the megablock amphibolite indicate an igneous protolith. The lower basement-derived granite also shows bulk chemical and mineralogical differences from the megablock gneissic and biotite granites. ?? 2009 The Geological Society of America.

  8. Basement Membrane-Based Glucose Sensor Coatings Enhance Continuous Glucose Monitoring in Vivo

    PubMed Central

    Klueh, Ulrike; Qiao, Yi; Czajkowski, Caroline; Ludzinska, Izabela; Antar, Omar; Kreutzer, Donald L.

    2015-01-01

    Background: Implantable glucose sensors demonstrate a rapid decline in function that is likely due to biofouling of the sensor. Previous efforts directed at overcoming this issue has generally focused on the use of synthetic polymer coatings, with little apparent effect in vivo, clearly a novel approach is required. We believe that the key to extending sensor life span in vivo is the development of biocompatible basement membrane (BM) based bio-hydrogels as coatings for glucose sensors. Method: BM based bio-hydrogel sensor coatings were developed using purified BM preparations (ie, Cultrex from Trevigen Inc). Modified Abbott sensors were coated with Cultrex BM extracts. Sensor performance was evaluated for the impact of these coatings in vitro and in vivo in a continuous glucose monitoring (CGM) mouse model. In vivo sensor function was assessed over a 28-day time period expressed as mean absolute relative difference (MARD) values. Tissue reactivity of both Cultrex coated and uncoated glucose sensors was evaluated at 7, 14, 21 and 28 days post–sensor implantation with standard histological techniques. Results: The data demonstrate that Cultrex-based sensor coatings had no effect on glucose sensor function in vitro. In vivo glucose sensor performance was enhanced following BM coating as determined by MARD analysis, particularly in weeks 2 and 3. In vivo studies also demonstrated that Cultrex coatings significantly decreased sensor-induced tissue reactions at the sensor implantation sites. Conclusion: Basement-membrane-based sensor coatings enhance glucose sensor function in vivo, by minimizing or preventing sensor-induced tissues reactions. PMID:26306494

  9. Basement Membrane-Based Glucose Sensor Coatings Enhance Continuous Glucose Monitoring in Vivo.

    PubMed

    Klueh, Ulrike; Qiao, Yi; Czajkowski, Caroline; Ludzinska, Izabela; Antar, Omar; Kreutzer, Donald L

    2015-08-25

    Implantable glucose sensors demonstrate a rapid decline in function that is likely due to biofouling of the sensor. Previous efforts directed at overcoming this issue has generally focused on the use of synthetic polymer coatings, with little apparent effect in vivo, clearly a novel approach is required. We believe that the key to extending sensor life span in vivo is the development of biocompatible basement membrane (BM) based bio-hydrogels as coatings for glucose sensors. BM based bio-hydrogel sensor coatings were developed using purified BM preparations (ie, Cultrex from Trevigen Inc). Modified Abbott sensors were coated with Cultrex BM extracts. Sensor performance was evaluated for the impact of these coatings in vitro and in vivo in a continuous glucose monitoring (CGM) mouse model. In vivo sensor function was assessed over a 28-day time period expressed as mean absolute relative difference (MARD) values. Tissue reactivity of both Cultrex coated and uncoated glucose sensors was evaluated at 7, 14, 21 and 28 days post-sensor implantation with standard histological techniques. The data demonstrate that Cultrex-based sensor coatings had no effect on glucose sensor function in vitro. In vivo glucose sensor performance was enhanced following BM coating as determined by MARD analysis, particularly in weeks 2 and 3. In vivo studies also demonstrated that Cultrex coatings significantly decreased sensor-induced tissue reactions at the sensor implantation sites. Basement-membrane-based sensor coatings enhance glucose sensor function in vivo, by minimizing or preventing sensor-induced tissues reactions. © 2015 Diabetes Technology Society.

  10. Improving Students' Educational Experience by Harnessing Digital Technology: elgg in the ODL Environment

    ERIC Educational Resources Information Center

    Tung, Lai Cheng

    2013-01-01

    Given the rising popularity of both open and distance learning (ODL) and social networking tools, it seems logical to merge and harness these two popular technologies with the goal of improving student educational experience. The integration seems to hold tremendous promise for the open and distance learning mode. To reduce the gap in the…

  11. Pakistan’s Law Enforcement Agencies -- Harnessing their Potential to Combat Terrorism

    DTIC Science & Technology

    2008-12-01

    can be easily varied, and that has been a common phenomenon in the recent past . 55 maintaining law and order in the province.145 This force...NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS Approved for pubic release; distribution is unlimited PAKISTAN’S LAW ...REPORT TYPE AND DATES COVERED Master’s Thesis 4. TITLE AND SUBTITLE: Pakistan’s Law Enforcement Agencies - Harnessing their Potential to Combat

  12. Geo-electrical investigation of near surface conductive structures suitable for groundwater accumulation in a resistive crystalline basement environment: A case study of Isuada, southwestern Nigeria

    NASA Astrophysics Data System (ADS)

    Kayode, J. S.; Adelusi, A. O.; Nawawi, M. N. M.; Bawallah, M.; Olowolafe, T. S.

    2016-07-01

    This paper presents a geophysical surveying for groundwater identification in a resistive crystalline basement hard rock in Isuada area, Southwestern Nigeria. Very low frequency (VLF) electromagnetic and electrical resistivity geophysical techniques combined with well log were used to characterize the concealed near surface conductive structures suitable for groundwater accumulation. Prior to this work; little was known about the groundwater potential of this area. Qualitative and semi-quantitative interpretations of the data collected along eight traverses at 20 m spacing discovered conductive zones suspected to be fractures, faults, and cracks which were further mapped using Vertical Electrical Sounding (VES) technique. Forty VES stations were utilized using Schlumberger configurations with AB/2 varying from 1 to 100 m. Four layers i.e. the top soil, the weathered layer, the partially weathered/fractured basement and the fresh basement were delineated from the interpreted resistivity curves. The weathered layers constitute the major aquifer unit in the area and are characterized by moderately low resistivity values which ranged between about 52 Ωm and 270 Ωm while the thickness varied from 1 to 35 m. The depth to the basement and the permeable nature of the weathered layer obtained from both the borehole and the hand-dug wells was used to categorize the groundwater potential of the study area into high, medium and low ratings. The groundwater potential map revealed that about 45% of the study area falls within the low groundwater potential rating while about 10% constitutes the medium groundwater potential and the remaining 45% constitutes high groundwater potential. The low resistivity, thick overburden, and fractured bedrock constitute the aquifer units and the series of basement depressions identified from the geoelectric sections as potential conductive zones appropriate for groundwater development.

  13. Studies of the permeation properties of glomerular basement membrane: cross-linking renders glomerular basement membrane permeable to protein.

    PubMed

    Walton, H A; Byrne, J; Robinson, G B

    1992-03-20

    Cross-linking glomerular basement membrane (GBM) has been shown to render it more permeable to protein. Isolated pig GBM was cross-linked with dimethylmalonimidate which reacts selectively with lysine epsilon-NH2 groups or with glutaraldehyde, a less selective cross-linking agent. Studies of the ultrafiltration properties of these materials in vitro using cytochrome c, myoglobin, bovine serum albumin and immunoglobulin showed that cross-linking had markedly increased solvent and protein fluxes as compared with native membranes particularly at higher pressures. Filtration studies with serum demonstrated that the cross-linked membranes were more permeable to serum proteins. Thickness measurements under pressure indicated that cross-linked membrane was less compressed than native membrane as pressure was increased. Pore theory did not provide a suitable model for analysis of the results, but analysis of the results using the fibre-matrix hypothesis indicated that cross-linking had the effect of bundling together the fibres (type IV collagen) in the GBM matrix. The effect of cross-linking on filtration could be explained by a combination of contraction of the membrane, fibre bundling and increased rigidity compared with native membrane. Cross-linking of GBM might lead to long-term damage of the glomerular capillary wall in nephritis, so promoting proteinuria.

  14. MTR,TRA603. EXPERIMENTERS' SPACE ALLOCATIONS IN BASEMENT AS OF 1963. SHIELDED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    MTR,TRA-603. EXPERIMENTERS' SPACE ALLOCATIONS IN BASEMENT AS OF 1963. SHIELDED CUBICLES WERE IDENTIFIED BY SPONSORING LABORATORY AND ITS TEST HOLE NUMBER IN THE REACTOR, IE, "KAPL HB-1" SIGNIFIED KNOLLS ATOMIC POWER LABORATORY, HORIZONTAL BEAM NO. 1. "WAPD" WAS WESTINGHOUSE ATOMIC POWER DIVISION. CATCH TANKS AND SAMPLE STATIONS FOR TEST LOOPS WERE ASSOCIATED WITH THESE CUBICLES. NOTE DESKS, STORAGE CABINETS, SWITCH GEAR, INSTRUMENT PANELS. PHILLIPS PETROLEUM COMPANY MTR-E-5205, 4/1963. INL INDEX NO. 531-0603-00-706-009757, REV. 5. - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  15. The pubo-femoral distance decreases with Pavlik harness treatment for developmental dysplasia of the hip in newborns.

    PubMed

    Maranho, Daniel Augusto; Donati, Felipe Nunes; Dalto, Vitor Faeda; Nogueira-Barbosa, Marcello Henrique

    2017-09-01

    To evaluate the evolution of the ultrasonographic pubo-femoral distance (PFD) before and after Pavlik harness treatment for developmental dysplasia of the hip (DDH) in newborns. Twenty-five patients (16.7 ± 10.4 days; 19 females, six males) diagnosed with DDH and treated using the Pavlik harness were included. Eighteen patients had bilateral, and seven unilateral DDH, with a total of 43 dysplastic hips. The seven non-dysplastic hips in unilateral cases were used for comparison. The PFD was measured in the coronal and axial planes with the hip flexed to approximately 90°, before and after an average of 93 days of treatment. The femoral head coverage was assessed in the coronal plane, and correlated with PFD values. In dysplastic hips, the mean PFD decreased from 6.1 ± 1.8 mm to 3.0 ± 0.7 mm in the axial (adjusted difference, 2.9 mm; p < 0.01), and from 5.9 ± 2.0 to 3.0 ± 0.6 mm in the coronal plane (adjusted difference 2.7 mm; p < 0.01). The femoral head coverage increased from 30.8 to 62.1%, and the mean differences of femoral head coverage and PFD were significantly correlated (p < 0.001). There was no difference between treated dysplastic and non-dysplastic hips. There was high intra- and inter-observer agreement for PFD measurements. The PFD decreased significantly after DDH treatment using the Pavlik harness in newborns, and showed significant correlation with the femoral head coverage improvement. PFD might be a reliable tool for monitoring DDH treatment in newborns treated using the Pavlik harness.

  16. "Hello, World!" Harnessing Social Media for the Rosetta Mission

    NASA Astrophysics Data System (ADS)

    Baldwin, E.; Mignone, C.; Scuka, D.; Homfeld, A. M.; Ranero, K.; Rolfe, E.; Bennett, M.; Schepers, A.; O'Flaherty, K. S.; Bauer, M.; McCaughrean, M.

    2016-03-01

    The European Space Agency's comet-chasing Rosetta mission was launched in 2004, before social media became a popular tool for mainstream communication. As it reached its destination ten years later, new audiences were reached and inspired by this once-in-a-lifetime event by harnessing a range of outlets for communicating the key messages. These included traditional online platforms, such as news websites, blogs, and Livestream, as well as Twitter, Facebook, Instagram, Flickr, YouTube, Google+ and SoundCloud. In this article, we outline the role social media channels played in making Rosetta one of the European Space Agency's biggest communication and public engagement successes.

  17. Preliminary model of the pre-Tertiary basement rocks beneath Yucca Flat, Nevada Test Site, Nevada, based on analysis of gravity and magnetic data

    USGS Publications Warehouse

    Phelps, Geoffrey A.; McKee, Edwin H.; Sweetkind, D.; Langenheim, V.E.

    2000-01-01

    The Environmental Restoration Program of the U.S. Department of Energy, Nevada Operations Office, was developed to investigate the possible consequences to the environment of 40 years of nuclear testing on the Nevada Test Site. The majority of the tests were detonated underground, introducing contaminants into the ground-water system (Laczniak and others, 1996). An understanding of the ground-water flow paths is necessary to evaluate the extent of ground-water contamination. This report provides information specific to Yucca Flat on the Nevada Test Site. Critical to understanding the ground-water flow beneath Yucca Flat is an understanding of the subsurface geology, particularly the structure and distribution of the pre-Tertiary rocks, which comprise both the major regional aquifer and aquitard sequences (Winograd and Thordarson, 1975; Laczniak and others, 1996). Because the pre-Tertiary rocks are not exposed at the surface of Yucca Flat their distribution must be determined through well logs and less direct geophysical methods such as potential field studies. In previous studies (Phelps and others, 1999; Phelps and Mckee, 1999) developed a model of the basement surface of the Paleozoic rocks beneath Yucca Flat and a series of normal faults that create topographic relief on the basement surface. In this study the basement rocks and structure of Yucca Flat are examined in more detail using the basement gravity anomaly derived from the isostatic gravity inversion model of Phelps and others (1999) and high-resolution magnetic data, as part of an effort to gain a better understanding of the Paleozoic rocks beneath Yucca Flat in support of groundwater modeling.

  18. Agrin is a major heparan sulfate proteoglycan in the human glomerular basement membrane.

    PubMed

    Groffen, A J; Ruegg, M A; Dijkman, H; van de Velden, T J; Buskens, C A; van den Born, J; Assmann, K J; Monnens, L A; Veerkamp, J H; van den Heuvel, L P

    1998-01-01

    Agrin is a heparan sulfate proteoglycan (HSPG) that is highly concentrated in the synaptic basal lamina at the neuromuscular junction (NMJ). Agrin-like immunoreactivity is also detected outside the NMJ. Here we show that agrin is a major HSPG component of the human glomerular basement membrane (GBM). This is in addition to perlecan, a previously characterized HSPG of basement membranes. Antibodies against agrin and against an unidentified GBM HSPG produced a strong staining of the GBM and the NMJ, different from that observed with anti-perlecan antibodies. In addition, anti-agrin antisera recognized purified GBM HSPG and competed with an anti-GBM HSPG monoclonal antibody in ELISA. Furthermore, both antibodies recognized a molecule that migrated in SDS-PAGE as a smear and had a molecular mass of approximately 200-210 kD after deglycosylation. In immunoelectron microscopy, agrin showed a linear distribution along the GBM and was present throughout the width of the GBM. This was again different from perlecan, which was exclusively present on the endothelial side of the GBM and was distributed in a nonlinear manner. Quantitative ELISA showed that, compared with perlecan, the agrin-like GBM HSPG showed a sixfold higher molarity in crude glomerular extract. These results show that agrin is a major component of the GBM, indicating that it may play a role in renal ultrafiltration and cell matrix interaction. (J Histochem Cytochem 46:19-27, 1998)

  19. Harnessing supramolecular peptide nanotechnology in biomedical applications.

    PubMed

    Chan, Kiat Hwa; Lee, Wei Hao; Zhuo, Shuangmu; Ni, Ming

    2017-01-01

    The harnessing of peptides in biomedical applications is a recent hot topic. This arises mainly from the general biocompatibility of peptides, as well as from the ease of tunability of peptide structure to engineer desired properties. The ease of progression from laboratory testing to clinical trials is evident from the plethora of examples available. In this review, we compare and contrast how three distinct self-assembled peptide nanostructures possess different functions. We have 1) nanofibrils in biomaterials that can interact with cells, 2) nanoparticles that can traverse the bloodstream to deliver its payload and also be bioimaged, and 3) nanotubes that can serve as cross-membrane conduits and as a template for nanowire formation. Through this review, we aim to illustrate how various peptides, in their various self-assembled nanostructures, possess great promise in a wide range of biomedical applications and what more can be expected.

  20. 17. VIEW SOUTHEAST OF 450 HP TURBINE IN BASEMENT OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. VIEW SOUTHEAST OF 450 HP TURBINE IN BASEMENT OF GRANITEVILLE MILL. THE MAIN BEARING OF THE TURBINE IS AT LEFT CENTER OF THE PHOTOGRAPH. A LOMBARD REGULATOR CAN BE SEEN AT THE LEFT CENTER REAR. THE LARGE HANDWHEEL AT THE LEFT CENTER IS GEARED TO A SECTIONAL GEAR AT THE CENTER OF THE PHOTOGRAPH AND IS USED TO MANUALLY OPEN THE GATES AND ALLOW WATER INTO THE TURBINE. THE SMALL PULLEY ON THE END OF THE MAIN SHAFT NORMALLY WOULD HAVE A BELT CONNECTING IT TO A PULLEY ON THE LOMBARD REGULATOR. THIS BELT TRANSMITTED TURBINE SPEED (RPM) TO THE LOMBARD WHICH WOULD OPEN OR CLOSE THE GATES TO KEEP TURBINE SPEED CONSTANT UNDER VARYING LOADS. THIS TURBINE WAS INSTALLED IN THE REFIT OF 1912. - Graniteville Mill, Marshall Street, Graniteville, Aiken County, SC

  1. 18. VIEW SOUTHWEST OF 450 HP TURBINE INSTALLATION IN BASEMENT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. VIEW SOUTHWEST OF 450 HP TURBINE INSTALLATION IN BASEMENT OF GRANITEVILLE MILL. MAIN FEATURE OF THE PHOTOGRAPH IS THE PENSTOCK CONDUCTING WATER TO THE TURBINE IN THE BACKGROUND. THE PENSTOCK IS OF RIVETED IRON CONSTRUCTION AND REPLACED A WOOD PENSTOCK IN 1882. THE COVERED OPENING IN THE CENTER OF THE PHOTOGRAPH ORIGINALLY CONNECTED TO A STANDPIPE WHICH EXITED VERTICALLY THROUGH THE MILL. THE STANDPIPE MODERATED WATER PRESSURE AND SERVED AS A SAFETY FEATURE IN THE EVENT THE TURBINE GATES WERE RAPIDLY CLOSED. (IF LOAD IN THE MILL WERE SUDDENLY STOPPED-SAY AT QUITTING TIME-THE GATES WOULD SHUT DOWN FLOW TO THE TURBINE. THE STANDPIPE OFFERED A PLACE FOR THE WATER, RAPIDLY MOVING THROUGH THE PENSTOCK, TO ESCAPE. IN A SHUT-DOWN SITUATION WATER WOULD ... - Graniteville Mill, Marshall Street, Graniteville, Aiken County, SC

  2. Detrital record of initial basement exhumation along the Laramide deformation front, southern Rocky Mountains

    NASA Astrophysics Data System (ADS)

    Bush, Meredith A.; Horton, Brian K.; Murphy, Michael A.; Stockli, Daniel F.

    2016-09-01

    New geochronological constraints on upper crustal exhumation in the southern Rocky Mountains help delineate the latest Cretaceous-Paleogene history of drainage reorganization and landscape evolution during Laramide flat-slab subduction beneath western North America. Detrital zircon U-Pb results for the Raton basin of southern Colorado and northern New Mexico define the inception of coarse-grained siliciclastic sedimentation and a distinctive shift in provenance, from distal to proximal sources, that recorded shortening-related uplift and unroofing along the Laramide deformation front of the northern Sangre de Cristo Mountains. This Maastrichtian-early Paleocene ( 70-65 Ma) change—from distal foreland accumulation of sediment derived from the thin-skinned Cordilleran (Sevier) fold-thrust belt to coarse-grained sedimentation proximal to a Laramide basement block uplift—reflects cratonward (eastward) deformation advance and reorganization of drainage systems that supplied a large volume of Paleocene-lower Eocene sediments to the Gulf of Mexico. The timing of unroofing along the eastern deformation front is synchronous with basement-involved shortening across the interior of the Laramide province, suggesting abrupt wholesale uplift rather than a systematic inboard advance of deformation. The growth and infilling of broken foreland basins within the interior and margins of the Laramide province had a significant impact on continental-scale drainage systems, as several ponded/axial Laramide basins trapped large volumes of sediment and induced reorganization of major source-to-sink sediment pathways.

  3. Plug-and-play design approach to smart harness for modular small satellites

    NASA Astrophysics Data System (ADS)

    Mughal, M. Rizwan; Ali, Anwar; Reyneri, Leonardo M.

    2014-02-01

    A typical satellite involves many different components that vary in bandwidth demand. Sensors that require a very low data rate may reside on a simple two- or three-wire interface such as I2C, SPI, etc. Complex sensors that require high data rate and bandwidth may reside on an optical interface. The AraMiS architecture is an enhanced capability architecture with different satellite configurations. Although keeping the low-cost and COTS approach of CubeSats, it extends the modularity concept as it also targets different satellite shapes and sizes. But modularity moves beyond the mechanical structure: the tiles also have thermo-mechanical, harness and signal-processing functionalities. Further modularizing the system, every tile can also host a variable number of small sensors, actuators or payloads, connected using a plug-and-play approach. Every subsystem is housed in a small daughter board and is supplied, by the main tile, with power and data distribution functions, power and data harness, mechanical support and is attached and interconnected with space-grade spring-loaded connectors. The tile software is also modular and allows a quick adaptation to specific subsystems. The basic software for the CPU is properly hardened to guarantee high level of radiation tolerance at very low cost.

  4. Peroxisystem: harnessing systems cell biology to study peroxisomes.

    PubMed

    Schuldiner, Maya; Zalckvar, Einat

    2015-04-01

    In recent years, high-throughput experimentation with quantitative analysis and modelling of cells, recently dubbed systems cell biology, has been harnessed to study the organisation and dynamics of simple biological systems. Here, we suggest that the peroxisome, a fascinating dynamic organelle, can be used as a good candidate for studying a complete biological system. We discuss several aspects of peroxisomes that can be studied using high-throughput systematic approaches and be integrated into a predictive model. Such approaches can be used in the future to study and understand how a more complex biological system, like a cell and maybe even ultimately a whole organism, works. © 2015 Société Française des Microscopies and Société de Biologie Cellulaire de France. Published by John Wiley & Sons Ltd.

  5. Cell therapy for basement membrane-linked diseases.

    PubMed

    Nyström, Alexander; Bornert, Olivier; Kühl, Tobias

    2017-01-01

    For most disorders caused by mutations in genes encoding basement membrane (BM) proteins, there are at present only limited treatment options available. Genetic BM-linked disorders can be viewed as especially suited for treatment with cell-based therapy approaches because the proteins that need to be restored are located in the extracellular space. In consequence, complete and permanent engraftment of cells does not necessarily have to occur to achieve substantial causal therapeutic effects. For these disorders cells can be used as transient vehicles for protein replacement. In addition, it is becoming evident that BM-linked genetic disorders are modified by secondary diseases mechanisms. Cell-based therapies have also the ability to target such disease modifying mechanisms. Thus, cell therapies can simultaneously provide causal treatment and symptomatic relief, and accordingly hold great potential for treatment of BM-linked disorders. However, this potential has for most applications and diseases so far not been realized. Here, we will present the state of cell therapies for BM-linked diseases. We will discuss use of both pluripotent and differentiated cells, the limitation of the approaches, their challenges, and the way forward to potential wider implementation of cell therapies in the clinics. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Radon entry into basements: Approach, experimental structures, and instrumentation of the small structures research project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fisk, W.J.; Modera, M.P.; Sextro, R.G.

    1992-02-01

    We describe the experimental approach, structures, and instrumentation of a research project on radon generation and transport in soil and entry into basements. The overall approach is to construct small precisely-fabricated basements in areas of different geology and climate, to control the pressures and ventilation rates in the structures, and to monitor radon concentrations and other relevant parameters over a period of one year or more. Two nearly air-tight structures have been constructed at the first site. The floor of each structure contains adjustable-width slots that serve as the only significant pathway for advective entry of radon. A layer ofmore » gravel underlays the floor of one structure; otherwise they are identical. The structures are instrumented for continuous or periodic monitoring of soil, structural, and meteorological parameters that affect radon entry. The pressure difference that drives advective radon entry can be maintained constant or varied over time. Soil gas and radon entry rates and associated parameters, such as soil gas pressures and radon concentrations, have been monitored for a range of steady-state and time-varying pressure differences between the interior of the structure and the soil. Examples of the experimentally-measured pressure and permeability fields in the soil around a structure are presented and discussed.« less

  7. Nanoscale protein architecture of the kidney glomerular basement membrane

    PubMed Central

    Suleiman, Hani; Zhang, Lei; Roth, Robyn; Heuser, John E; Miner, Jeffrey H; Shaw, Andrey S; Dani, Adish

    2013-01-01

    In multicellular organisms, proteins of the extracellular matrix (ECM) play structural and functional roles in essentially all organs, so understanding ECM protein organization in health and disease remains an important goal. Here, we used sub-diffraction resolution stochastic optical reconstruction microscopy (STORM) to resolve the in situ molecular organization of proteins within the kidney glomerular basement membrane (GBM), an essential mediator of glomerular ultrafiltration. Using multichannel STORM and STORM-electron microscopy correlation, we constructed a molecular reference frame that revealed a laminar organization of ECM proteins within the GBM. Separate analyses of domains near the N- and C-termini of agrin, laminin, and collagen IV in mouse and human GBM revealed a highly oriented macromolecular organization. Our analysis also revealed disruptions in this GBM architecture in a mouse model of Alport syndrome. These results provide the first nanoscopic glimpse into the organization of a complex ECM. DOI: http://dx.doi.org/10.7554/eLife.01149.001 PMID:24137544

  8. In vivo laser confocal microscopy findings in patients with map-dot-fingerprint (epithelial basement membrane) dystrophy.

    PubMed

    Kobayashi, Akira; Yokogawa, Hideaki; Sugiyama, Kazuhisa

    2012-01-01

    The purpose of this study was to investigate pathological changes of the corneal cell layer in patients with map-dot-fingerprint (epithelial basement membrane) dystrophy by in vivo laser corneal confocal microscopy. Two patients were evaluated using a cornea-specific in vivo laser scanning confocal microscope (Heidelberg Retina Tomograph 2 Rostock Cornea Module, HRT 2-RCM). The affected corneal areas of both patients were examined. Image analysis was performed to identify corneal epithelial and stromal deposits correlated with this dystrophy. Variously shaped (linear, multilaminar, curvilinear, ring-shape, geographic) highly reflective materials were observed in the "map" area, mainly in the basal epithelial cell layer. In "fingerprint" lesions, multiple linear and curvilinear hyporeflective lines were observed. Additionally, in the affected corneas, infiltration of possible Langerhans cells and other inflammatory cells was observed as highly reflective Langerhans cell-like or dot images. Finally, needle-shaped materials were observed in one patient. HRT 2-RCM laser confocal microscopy is capable of identifying corneal microstructural changes related to map-dot-fingerprint corneal dystrophy in vivo. The technique may be useful in elucidating the pathogenesis and natural course of map-dot-fingerprint corneal dystrophy and other similar basement membrane abnormalities.

  9. Peninsular terrane basement ages recorded by Paleozoic and Paleoproterozoic zircon in gabbro xenoliths and andesite from Redoubt volcano, Alaska

    USGS Publications Warehouse

    Bacon, Charles R.; Vazquez, Jorge A.; Wooden, Joseph L.

    2012-01-01

    Historically Sactive Redoubt volcano is an Aleutian arc basalt-to-dacite cone constructed upon the Jurassic–Early Tertiary Alaska–Aleutian Range batholith. The batholith intrudes the Peninsular tectonostratigraphic terrane, which is considered to have developed on oceanic basement and to have accreted to North America, possibly in Late Jurassic time. Xenoliths in Redoubt magmas have been thought to be modern cumulate gabbros and fragments of the batholith. However, new sensitive high-resolution ion microprobe (SHRIMP) U-Pb ages for zircon from gabbro xenoliths from a late Pleistocene pyroclastic deposit are dominated by much older, ca. 310 Ma Pennsylvanian and ca. 1865 Ma Paleoproterozoic grains. Zircon age distributions and trace-element concentrations indicate that the ca. 310 Ma zircons date gabbroic intrusive rocks, and the ca. 1865 Ma zircons also are likely from igneous rocks in or beneath Peninsular terrane basement. The trace-element data imply that four of five Cretaceous–Paleocene zircons, and Pennsylvanian low-U, low-Th zircons in one sample, grew from metamorphic or hydrothermal fluids. Textural evidence of xenocrysts and a dominant population of ca. 1865 Ma zircon in juvenile crystal-rich andesite from the same pyroclastic deposit show that this basement has been assimilated by Redoubt magma. Equilibration temperatures and oxygen fugacities indicated by Fe-Ti–oxide minerals in the gabbros and crystal-rich andesite suggest sources near the margins of the Redoubt magmatic system, most likely in the magma accumulation and storage region currently outlined by seismicity and magma petrology at ∼4–10 km below sea level. Additionally, a partially melted gabbro from the 1990 eruption contains zircon with U-Pb ages between ca. 620 Ma and ca. 1705 Ma, as well as one zircon with a U-Th disequilibrium model age of 0 ka. The zircon ages demonstrate that Pennsylvanian, and probably Paleoproterozoic, igneous rocks exist in, or possibly beneath, Peninsular

  10. Prospects for harnessing biocide resistance for bioremediation and detoxification.

    PubMed

    Atashgahi, Siavash; Sánchez-Andrea, Irene; Heipieper, Hermann J; van der Meer, Jan R; Stams, Alfons J M; Smidt, Hauke

    2018-05-18

    Prokaryotes in natural environments respond rapidly to high concentrations of chemicals and physical stresses. Exposure to anthropogenic toxic substances-such as oil, chlorinated solvents, or antibiotics-favors the evolution of resistant phenotypes, some of which can use contaminants as an exclusive carbon source or as electron donors and acceptors. Microorganisms similarly adapt to extreme pH, metal, or osmotic stress. The metabolic plasticity of prokaryotes can thus be harnessed for bioremediation and can be exploited in a variety of ways, ranging from stimulated natural attenuation to bioaugmentation and from wastewater treatment to habitat restoration. Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

  11. World Bank: harnessing civil society expertise in undertaking and disseminating research findings.

    PubMed

    Simms, Ben

    2013-01-01

    The UK Consortium on AIDS and International Development was an essential partner to the evaluation leaders in harnessing the contribution and expertise of civil society. This article describes what the partnership entailed, the additional value it brought and how civil society might use the evaluation findings both as a tool for advocacy and a means for improving its own engagement with the individuals directly affected by HIV and with those who care for them.

  12. Relative prevalence of upper respiratory tract obstructive disorders in two breeds of harness racehorses (185 cases: 1998-2006).

    PubMed

    Strand, E; Fjordbakk, C T; Sundberg, K; Spangen, L; Lunde, H; Hanche-Olsen, S

    2012-09-01

    Two genetically and phenotypically distinct horse breeds are used for harness racing in Scandinavia: the Standardbred (SB) and Coldblooded Trotter. These racehorses have identical environmental, management and racing conditions. Therefore, this study was undertaken to identify and compare the relative prevalence of upper respiratory tract (URT) obstructive disorders in these 2 breeds. To determine whether these 2 phenotypically different breeds of harness racehorses have different predispositions for URT disorders. Retrospective study of 88 Norwegian Coldblooded Trotters (NCT) and 97 SBs referred to this hospital for URT evaluation between 1998 and 2006. Case records of all horses diagnosed with an URT disorder during resting endoscopy, and all horses undergoing high-speed treadmill videoendoscopy (HSTV) with one or more periods of induced poll flexion were evaluated. The relative prevalence of URT disorders between the 2 breeds was analysed using a Fisher's exact test. There was a significant (P<0.05) breed predisposition regarding 6 URT disorders. Bilateral dynamic laryngeal collapse associated with poll flexion and flaccid epiglottis was significantly more frequent in the NCT. Alar fold collapse and nasopharyngeal collapse were significantly more frequent in SBs. Epiglottic entrapment and nasal flutter were only diagnosed in the SBs. Dynamic disorders were more common than resting disorders in both breeds. URT obstructive disorders (dynamic laryngeal collapse associated with poll flexion, flaccid epiglottis, pharyngeal collapse, alar fold collapse, nasal flutter and epiglottic entrapment) are breed related, indicating an anatomic or functional cause. Periods of induced poll flexion during HSTV was essential to declare harness racehorses free of URT disorders. Further anatomic or physiological studies comparing these breeds could potentially provide insight into the pathogenesis of certain URT obstructive disorders. Induced poll flexion should be included in

  13. Overexpression of β1-chain-containing laminins in capillary basement membranes of human breast cancer and its metastases

    PubMed Central

    Fujita, Manabu; Khazenzon, Natalya M; Bose, Shikha; Sekiguchi, Kiyotoshi; Sasaki, Takako; Carter, William G; Ljubimov, Alexander V; Black, Keith L; Ljubimova, Julia Y

    2005-01-01

    Introduction Laminins are the major components of vascular and parenchymal basement membranes. We previously documented a switch in the expression of vascular laminins containing the α4 chain from predominantly laminin-9 (α4β2γ1) to predominantly laminin-8 (α4β1γ1) during progression of human brain gliomas to high-grade glioblastoma multiforme. Here, differential expression of laminins was studied in blood vessels and ductal epithelium of the breast. Method In the present study the expressions of laminin isoforms α1–α5, β1–β3, γ1, and γ2 were examined during progression of breast cancer. Forty-five clinical samples of breast tissues including normal breast, ductal carcinomas in situ, invasive ductal carcinomas, and their metastases to the brain were compared using Western blot analysis and immunohistochemistry for various chains of laminin, in particular laminin-8 and laminin-9. Results Laminin α4 chain was observed in vascular basement membranes of most studied tissues, with the highest expression in metastases. At the same time, the expression of laminin β2 chain (a constituent of laminin-9) was mostly seen in normal breast and carcinomas in situ but not in invasive carcinomas or metastases. In contrast, laminin β1 chain (a constituent of laminin-8) was typically found in vessel walls of carcinomas and their metastases but not in those of normal breast. The expression of laminin-8 increased in a progression-dependent manner. A similar change was observed from laminin-11 (α5β2γ1) to laminin-10 (α5β1γ1) during breast tumor progression. Additionally, laminin-2 (α2β1γ1) appeared in vascular basement membranes of invasive carcinomas and metastases. Chains of laminin-5 (α3β3γ2) were expressed in the ductal epithelium basement membranes of the breast and diminished with tumor progression. Conclusion These results suggest that laminin-2, laminin-8, and laminin-10 are important components of tumor microvessels and may associate with breast

  14. Harnessing extracellular vesicles to direct endochondral repair of large bone defects

    PubMed Central

    Ferreira, E.

    2018-01-01

    Large bone defects remain a tremendous clinical challenge. There is growing evidence in support of treatment strategies that direct defect repair through an endochondral route, involving a cartilage intermediate. While culture-expanded stem/progenitor cells are being evaluated for this purpose, these cells would compete with endogenous repair cells for limited oxygen and nutrients within ischaemic defects. Alternatively, it may be possible to employ extracellular vesicles (EVs) secreted by culture-expanded cells for overcoming key bottlenecks to endochondral repair, such as defect vascularization, chondrogenesis, and osseous remodelling. While mesenchymal stromal/stem cells are a promising source of therapeutic EVs, other donor cells should also be considered. The efficacy of an EV-based therapeutic will likely depend on the design of companion scaffolds for controlled delivery to specific target cells. Ultimately, the knowledge gained from studies of EVs could one day inform the long-term development of synthetic, engineered nanovesicles. In the meantime, EVs harnessed from in vitro cell culture have near-term promise for use in bone regenerative medicine. This narrative review presents a rationale for using EVs to improve the repair of large bone defects, highlights promising cell sources and likely therapeutic targets for directing repair through an endochondral pathway, and discusses current barriers to clinical translation. Cite this article: E. Ferreira, R. M. Porter. Harnessing extracellular vesicles to direct endochondral repair of large bone defects. Bone Joint Res 2018;7:263–273. DOI: 10.1302/2046-3758.74.BJR-2018-0006. PMID:29922444

  15. Tectonothermal evolution of the Triassic flysch in the Bayan Har Orogen, Tibetan plateau

    NASA Astrophysics Data System (ADS)

    Wang, Hejing; Rahn, Meinert; Zhou, Jian

    2018-01-01

    The Bayan Har Orogen comprises a major part of the "Qingzang-Dianxi fold region" in western China. It preserves important information of the tectono-thermal evolution covering the time span from the closure of the Paleo-Tethys Ocean up to the formation of the Himalayas. Low temperature metamorphic indicators, such as mineral assemblages, illite "crystallinity" (IC), chlorite "crystallinity" (CC), illite polytype, b-cell dimension of K-white micas, geothermometry of selected minerals were analyzed. The values of Kübler index (KI) of the Triassic flysch in the Bayan Har Orogen range from 0.23-1.63°Δ2θ while Árkai index (ÁI) in a range of 0.21-0.60°Δ2θ. Iso-thermal zones mapped with KI describe a pair of anchizones and an anchiregion within the Bayan Har Orogen: the "Giant Yushu Anchizone" in the southwest (extending > 750 km long and 100 km wide), the "Zaling-Eling-Lakes Anchizone" in the center (about 150 km long and 40 km wide) and the "Xing-Tong-Zhe Anchiregion" in the northeast (covering an area of roughly 60,000 km2). They are separated by diagenetic zones. Peak metamorphic conditions are estimated around 280-330 °C and a low to intermediate (N. New Hampshire) pressure type. A slight change with increasing then decreasing pressure was observed from SW to NE. The relationship between anchimetamorphic pattern of Triassic flysch and large-scale folds and faults indicates syn- to post structural metamorphism. Compression at the end of the Triassic, induced by the interaction of the Tarim, North China and Indian blocks caused the closure of the Paleo-Tethys Ocean and led to the folding of the Triassic flysch within the Paleo-Tethys Ocean basin. Anchimetamorphism may have been caused by crustal thickening of > 10 km due to an accretionary wedge setting and a temperature increase in those rocks due to burial. Such a regional metamorphic pattern would provide important information for reconstruction of palaeotectonic-palaeogeograph and the evolutionary history

  16. Nature of the basement of the East Anatolian plateau: Implications for the lithospheric foundering processes

    NASA Astrophysics Data System (ADS)

    Topuz, G.; Candan, O.; Zack, T.; Yılmaz, A.

    2017-12-01

    The East Anatolian Plateau (Turkey) is characterized by (1) an extensive volcanic-sedimentary cover of Neogene to Quaternary age, (2) crustal thicknesses of 42-50 km, and (3) an extremely thinned lithospheric mantle. Its basement beneath the young cover is thought to consist of oceanic accretionary complexes of Late Cretaceous to Oligocene age. The attenuated state of the lithospheric mantle and the causes of the young volcanism are accounted for by slab steepening and subsequent break-off. We present field geological, petrological and geochronological data on three basement inliers (Taşlıçay, Akdağ and Ilıca) in the region. These areas are made up of amphibolite- to granulite-facies rocks, comprising marble, amphibolite, metapelite, quartzite and metagranite. The granulite-facies domain is equilibrated at 0.7 GPa and 800 ˚C at 83 ± 2 Ma (2σ). The metamorphic rocks are intruded by subduction-related coeval gabbroic, quartz monzonitic to tonalitic rocks. Both the metamorphic rocks and the intrusions are tectonically overlain by ophiolitic rocks. All these crystalline rocks are unconformably overlain by lower Maastrichtien clastic rocks and reefal limestone, suggesting that the exhumation at the earth's surface and juxtaposition with ophiolitic rocks occurred by early Maastrichtien. U-Pb dating on igneous zircon from metagranite yielded a protolith age of 445 ± 10 Ma (2σ). The detrital zircons from a metaquartzite point to Neoproterozoic to Early Paleozoic provenance. All these data favor a more or less continuous continental substrate to the allochthonous ophiolitic rocks beneath the young volcanic-sedimentary cover. The metamorphism and coeval magmatism can be regarded as the middle- to lower-crustal root of the Late Cretaceous magmatic arc that developed due to northward subduction along the Bitlis-Zagros suture. The presence of a continental basement beneath the young cover requires that the loss of the lithospheric mantle from beneath the East

  17. Biogeochemistry of dissolved methane and hydrogen in basement fluids of the sediment-buried Juan de Fuca Ridge flank at Boreholes (CORKs) 1301A, 1362A and 1362B: methane isotopic compositions

    NASA Astrophysics Data System (ADS)

    Lin, H.; Cowen, J. P.; Olson, E. J.; Lilley, M. D.; Jungbluth, S.; Rappe, M. S.

    2013-12-01

    The ocean crust is the largest aquifer system on Earth. Within the sediment-buried 3.5 Myr basaltic crust of the eastern Juan de Fuca Ridge (JFR) flank, the circulating basement fluids have moderate temperature (~65°C) and potentially harbor a substantial subseafloor biosphere. With dissolved oxygen and nitrate exhausted, sulfate may serve as the major electron acceptor in this environment. This study aims to evaluate the availability and the biogeochemistry of two important electron donors, methane and hydrogen, for the subseafloor biosphere. Basement fluids were collected via stainless steel and ethylene-tetrafluoroethylene fluoropolymer (ETFE) fluid delivery lines associated with Integrated Ocean Drilling Program (IODP) Circulation Obviation Retrofit Kits (CORKs) that extend from basement depths to outlet ports at the seafloor. Three CORKs were visited; 1301A, 1362A and 1362B lie within 200 to 500 m of each other, and their fluid intakes lie at ~30, ~60, and ~50 m below the sediment-basement interface (mbs), respectively. In addition, CORK 1362A contains a second intake at a deep (~200 mbs) horizon. The basement fluids from the three CORKs contained significantly higher concentrations of methane (1.5-13μM) and hydrogen (0.05-1.1 μM) than in bottom seawater (0.002 and 0.0004, respectively), indicating that prevalence and availability of both methane and hydrogen as electron donors for the subseafloor biosphere. Thermodynamic calculations show that sulfate reduction coupled with either methane or hydrogen oxidation is energy yielding in the oceanic basement. The δ13C values of methane ranged from -43×1‰ to -58×0.3‰; the δ2H values of methane in CORKs 1301A, 1362A and 1362B fluids were 57×5‰, -262×2‰, -209×2‰, respectively. The isotopic compositions suggest that methane in the basement fluid is of biogenic origin. Interestingly, the δ2H value of methane in the CORK 1301A fluids is far more positive than that in other marine environments

  18. Parachuting harnesses comparative evaluation on energy distribution grids.

    PubMed

    Hembecker, Paula Karina; Poletto, Angela Regina; Gontijo, Leila Amaral

    2012-01-01

    This research aims to make a comparative evaluation of three different parachuting harnesses to work at heights in the energy industry, from the electricians' point of view concerning these products under the optics of usability and ergonomic principles, and mainly justified by the high quantity of injuries at the energy industry due to high falls. According to its main target, this field research is classified as exploratory-descriptive transversal viewing study and, considering this perspective, the study was developed in four steps. Research results have enlightened the weakest spots and the potential improvement opportunities of these products, developed to assure safety of the work at heights to the energy industry, according to the opinion of the users. Still, results point that, regardless of the model, these devices have adapting issues to fulfill the electrical sector user's needs.

  19. Map showing depth to pre-Cenozoic basement in the Death Valley ground-water model area, Nevada and California

    USGS Publications Warehouse

    Blakely, R.J.; Ponce, D.A.

    2001-01-01

    A depth to basement map of the Death Valley groundwater model area was prepared using over 40,0000 gravity stations as part of an interagency effort by the U.S. Geological Survey and the U.S. Department of Energy to help characterize the geology and hydrology of southwest Nevada and parts of California.

  20. Geochemical, microtextural and petrological studies of the Samba prospect in the Zambian Copperbelt basement: a metamorphosed Palaeoproterozoic porphyry Cu deposit.

    NASA Astrophysics Data System (ADS)

    Master, Sharad; Mirrander Ndhlovu, N.

    2015-04-01

    Ever since Wakefield (1978, IMM Trans., B87, 43-52) described a porphyry-type meta-morphosed Cu prospect, the ca 50 Mt, 0.5% Cu Samba deposit (12.717°S, 27.833°E), hosted by porphyry-associated quartz-sericite-biotite schists in northern Zambia, there has been controversy about its origin and significance. This is because it is situated in the basement to the world's largest stratabound sediment-hosted copper province, the Central African Copperbelt, which is hosted by rocks of the Neoproterozoic Katanga Supergroup. Mineralization in the pre-Katangan basement has long played a prominent role in ore genetic models, with some authors suggesting that basement Cu mineralization may have been recycled into the Katangan basin through erosion and redeposition, while others have suggested that the circulation of fluids through Cu-rich basement may have leached out the metals which are found concentrated in the Katangan orebodies. On the basis of ca 490-460 Ma Ar-Ar ages, Hitzman et al. (2012, Sillitoe Vol., SEG Spec. Publ., 16, 487-514) suggested that Samba represents late-stage impregnation of copper mineralization into the basement, and that it was one of the youngest copper deposits known in the Central African Copperbelt. If the Samba deposit really is that young, then it would have post-dated regional deformation and metamorphism (560-510 Ma), and it ought to be undeformed and unmetamorphosed. The Samba mineralization consists of chalcopyrite and bornite, occurring as disseminations, stringers and veinlets, found in a zone >1 km along strike, in steeply-dipping lenses up to 10m thick and >150m deep. Our new major and trace element XRF geochemical data (14 samples) show that the host rocks are mainly calc-alkaline metadacites. Cu is correlated with Ag (Cu/Ag ~10,000:1) with no Au or Mo. Our study focused on the microtextures and petrology of the Samba ores. We confirm that there is alteration of similar style to that accompanying classical porphyry Cu mineralization

  1. Zebrafish collagen XII is present in embryonic connective tissue sheaths (fascia) and basement membranes.

    PubMed

    Bader, Hannah L; Keene, Douglas R; Charvet, Benjamin; Veit, Guido; Driever, Wolfgang; Koch, Manuel; Ruggiero, Florence

    2009-01-01

    Connective tissues ensure the cohesion of the tissues of the body, but also form specialized structures such as tendon and bone. Collagen XII may enhance the stability of connective tissues by bridging collagen fibrils, but its function is still unclear. Here, we used the zebrafish model to visualize its expression pattern in the whole organism. The zebrafish col12a1 gene is homologous to the small isoform of the tetrapod col12a1 gene. In agreement with the biochemical data reported for the small isoform, the zebrafish collagen XII alpha1 chain was characterized as a collagenase sensitive band migrating at approximately 200 kDa. Using newly generated polyclonal antibodies and anti-sense probes, we performed a comprehensive analysis of its expression in developing zebrafish. Collagen XII exhibited a much broader expression pattern than previously thought: it was ubiquitously expressed in the connective tissue sheaths (fascia) that encase the tissues and organs of the body. For example, it was found in sclera, meninges, epimysia and horizontal and vertical myosepta. Collagen XII was also detected in head mesenchyme, pharyngeal arches and within the spinal cord, where it was first expressed within and then at the lateral borders of the floor plate and at the dorsal midline. Furthermore, double immunofluorescence staining with laminin and immunogold electron microscopy revealed that collagen XII is associated with basement membranes. These data suggest that collagen XII is implicated in tissue cohesion by stabilizing fascia and by linking fascia to basement membranes.

  2. Water gate array for current flow or tidal movement pneumatic harnessing system

    DOEpatents

    Gorlov, Alexander M.

    1991-01-01

    The invention, which provides a system for harnessing power from current flow or tidal movement in a body of water, comprises first and second hydro-pneumatic chambers each having ingress and egress below the water surface near the river or ocean floor and water gates operative to open or seal the ports to the passage of water. In an exemplary embodiment, the gates are sychronized by shafts so that the ingress ports of each chamber are connected to the egress ports of each other chamber. Thus, one set of gates is closed, while the other is open, thereby allowing water to flow into one chamber and build air pressure therein and allowing water to flow out of the other chamber and create a partial vacuum therein. A pipe connects the chambers, and an air turbine harnesses the air movement within the pipe. When water levels are equilibrated, the open set of gates is closed by a counterweight, and the other set is allowed to open by natural force of the water differential. The water gates may be comprised of a plurality of louvers which are ganged for simultaneous opening and closing. The system is designed to operate with air turbines or other pneumatic devices. Its design minimizes construction cost and environmental impact, yet provides a clean renewable energy source.

  3. Regional differences in the morphological and functional effects of aging on cerebral basement membranes and perivascular drainage of amyloid-β from the mouse brain.

    PubMed

    Hawkes, Cheryl A; Gatherer, Maureen; Sharp, Matthew M; Dorr, Adrienne; Yuen, Ho Ming; Kalaria, Rajesh; Weller, Roy O; Carare, Roxana O

    2013-04-01

    Development of cerebral amyloid angiopathy (CAA) and Alzheimer's disease (AD) is associated with failure of elimination of amyloid-β (Aβ) from the brain along perivascular basement membranes that form the pathways for drainage of interstitial fluid and solutes from the brain. In transgenic APP mouse models of AD, the severity of cerebral amyloid angiopathy is greater in the cerebral cortex and hippocampus, intermediate in the thalamus, and least in the striatum. In this study we test the hypothesis that age-related regional variation in (1) vascular basement membranes and (2) perivascular drainage of Aβ contribute to the different regional patterns of CAA in the mouse brain. Quantitative electron microscopy of the brains of 2-, 7-, and 23-month-old mice revealed significant age-related thickening of capillary basement membranes in cerebral cortex, hippocampus, and thalamus, but not in the striatum. Results from Western blotting and immunocytochemistry experiments showed a significant reduction in collagen IV in the cortex and hippocampus with age and a reduction in laminin and nidogen 2 in the cortex and striatum. Injection of soluble Aβ into the hippocampus or thalamus showed an age-related reduction in perivascular drainage from the hippocampus but not from the thalamus. The results of the study suggest that changes in vascular basement membranes and perivascular drainage with age differ between brain regions, in the mouse, in a manner that may help to explain the differential deposition of Aβ in the brain in AD and may facilitate development of improved therapeutic strategies to remove Aβ from the brain in AD. © 2013 The Authors Aging Cell © 2013 Blackwell Publishing Ltd/Anatomical Society of Great Britain and Ireland.

  4. In vivo laser confocal microscopy findings in patients with map-dot-fingerprint (epithelial basement membrane) dystrophy

    PubMed Central

    Kobayashi, Akira; Yokogawa, Hideaki; Sugiyama, Kazuhisa

    2012-01-01

    Background: The purpose of this study was to investigate pathological changes of the corneal cell layer in patients with map-dot-fingerprint (epithelial basement membrane) dystrophy by in vivo laser corneal confocal microscopy. Methods: Two patients were evaluated using a cornea-specific in vivo laser scanning confocal microscope (Heidelberg Retina Tomograph 2 Rostock Cornea Module, HRT 2-RCM). The affected corneal areas of both patients were examined. Image analysis was performed to identify corneal epithelial and stromal deposits correlated with this dystrophy. Results: Variously shaped (linear, multilaminar, curvilinear, ring-shape, geographic) highly reflective materials were observed in the “map” area, mainly in the basal epithelial cell layer. In “fingerprint” lesions, multiple linear and curvilinear hyporeflective lines were observed. Additionally, in the affected corneas, infiltration of possible Langerhans cells and other inflammatory cells was observed as highly reflective Langerhans cell-like or dot images. Finally, needle-shaped materials were observed in one patient. Conclusion: HRT 2-RCM laser confocal microscopy is capable of identifying corneal microstructural changes related to map-dot-fingerprint corneal dystrophy in vivo. The technique may be useful in elucidating the pathogenesis and natural course of map-dot-fingerprint corneal dystrophy and other similar basement membrane abnormalities. PMID:22888214

  5. Transition through co-optation: Harnessing carbon democracy for clean energy

    NASA Astrophysics Data System (ADS)

    Meng, Kathryn-Louise

    This dissertation explores barriers to a clean energy transition in the United States. Clean energy is demonstrably viable, yet the pace of clean energy adoption in the U.S. is slow, particularly given the immediate threat of global climate change. The purpose of this dissertation is to examine the factors inhibiting a domestic energy transition and to propose pragmatic approaches to catalyzing a transition. The first article examines the current political-economic and socio-technical energy landscape in the U.S. Fossil fuels are central to the functioning of the American economy. Given this centrality, constellations of power have been constructed around the reliable and affordable access of fossil fuels. The fossil fuel energy regime is comprised of: political-economic networks with vested interests in continued fossil fuel reliance, and fixed infrastructure that is minimally compatible with distributed generation. A transition to clean energy threatens the profitability of fossil fuel regime actors. Harnessing structural critiques from political ecology and process and function-oriented socio-technical systems frameworks, I present a multi-level approach to identifying pragmatic means to catalyzing an energy transition. High-level solutions confront the existing structure, mid-level solutions harness synergy with the existing structure, and low-level solutions lie outside of the energy system or foster the TIS. This is exemplified using a case study of solar development in Massachusetts. Article two presents a case study of the clean energy technological innovation system (TIS) in Massachusetts. I examine the actors and institutions that support cleantech development. Further, I scrutinize the actors and institutions that help sustain the TIS support system. The concept of a catalyst is presented; a catalyst is an actor that serves to propel TIS functions. Catalysts are critical to facilitating anchoring. Strategic corporate partners are identified as powerful

  6. New zircon ages on the Cambrian-Ordovician volcanism of the Southern Gemericum basement (Western Carpathians, Slovakia): SHRIMP dating, geochemistry and provenance

    NASA Astrophysics Data System (ADS)

    Vozárová, Anna; Rodionov, Nickolay; Šarinová, Katarína; Presnyakov, Sergey

    2017-09-01

    The Southern Gemericum basement in the Inner Western Carpathians, composed of low-grade volcano-sedimentary rock complexes, constitutes a record of the polyphase Cambrian-Ordovician continental volcanic arc volcanism. These metavolcanic rocks are characterized by the enrichment in K, Rb, Ba, Th and Ce and Sm relative to Ta, Nb, Hf, Zr, Y and Yb that are the characteristic features for volcanic arc magmatites. The new SHRIMP U-Pb zircon data and compilation of previously published and re-evaluated zircon ages, contribute to a new constrain of the timing of the Cambrian-Ordovician volcanism that occurred between 496 and 447 Ma. The following peaks of the volcanic activity of the Southern Gemericum basement have been recognized: (a) mid-late Furongian at 492 Ma; (b) Tremadocian at 481 Ma; (c) Darriwilian at 464 Ma prolonged to 453 Ma within the early Upper Ordovician. The metavolcanic rocks are characterized by a high zircon inheritance, composed of Ediacaran (650-550 Ma), Tonian-Stenian (1.1-0.9 Ma), and, to a lesser extent, Mesoproterozoic (1.3 Ga), Paleoproterozoic (1.9 Ga) and Archaean assemblages (2.6 Ga). Based on the acquired zircon populations, it could be deduced that Cambrian-Ordovician arc crust was generated by a partial melting of Ediacaran basement in the subduction-related setting, into which old crustal fragments were incorporated. The ascertained zircon inheritances with Meso-, Paleoproterozoic and Archaean cores indicate the similarities with the Saharan Metacraton provenance.

  7. 3D model of Campo de Dalías basement from H/V spectral ratio of ambient seismic noise

    NASA Astrophysics Data System (ADS)

    García-Jerez, Antonio; Seivane, Helena; Luzón, Francisco; Navarro, Manuel; Molina, Luis; Aranda, Carolina; Piña-Flores, José; Navarro, Francisco; Sánchez-Martos, Francisco; Vidal, Francisco; Posadas, Antonio M.; Sánchez-Sesma, Francisco J.

    2017-04-01

    Campo de Dalías is a large coastal plain in the southeastern mountain front of the Betic Cordillera (SE of the Iberian Peninsula), being one of the most seismically active regions of Spain. This area has a population of about 213.000 inhabitants, with a high growth rate during the last decades due to the development of intensive agricultural activities. Seismic risk assessment and hydrogeological issues are major topics of interest for this area, relaying on the knowledge of the geophysical properties of the basin. A passive seismic survey has been conducted throughout the basin. We have recorded ambient noise at 340 sites located approximately on the vertexes of a 1000 x 1000 m square grid, as well as around a set of deep boreholes reaching the Triassic basement. These broad-band records, of at least 45 minutes long each, have been analyzed by using the horizontal-to-vertical spectral ratio method (H/V). The spectral analysis shows clear H/V peaks with periods ranging from 0.3 s to 4 s, approximately, associated to relevant contrasts in S-wave velocity (Vs) at depth. Simulations based on the diffuse field approach (Sánchez-Sesma et al. 2011) show that long periods are explained by the effect of several hundred meters of soft sedimentary rocks (mainly Miocene marls). Well-developed high-frequency secondary peaks have been found in some specific zones (e.g. N of Roquetas de Mar town). Then, fundamental frequencies and basement depths at borehole sites have been fitted by means of a power law, which can be applied down to 900 - 970m. Larger depths are estimated by extrapolation. This relationship has been used to map the basement (main Vs contrast) throughout the plain. The prospected basement model describes well the main structural features of this smoothly folded region, namely, the El Ejido Synform and the Guardias Viejas Antiform, with ENE-WSW-trend. These features are shifted toward the south in comparison with Pedrera et al. (2015). The homogeneous

  8. Hydrothermal origin of oil and gas reservoirs in basement rock of the South Vietnam continental shelf

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dmitriyevskiy, A.N.; Kireyev, F.A.; Bochko, R.A.

    1993-07-01

    Oil-saturated granites, with mineral parageneses typical of hydrothermal metasomatism and leaching haloes, have been found near faults in the crystalline basement of the South Vietnam continental shelf. The presence of native silver, barite, zincian copper, and iron chloride indicates a deep origin for the mineralizing fluids. Hydrothermally altered granites are a new possible type of reservoir and considerably broaden the possibilities of oil and gas exploration. 15 refs., 22 figs., 1 tab.

  9. Harnessing adolescent values to motivate healthier eating

    PubMed Central

    Bryan, Christopher J.; Yeager, David S.; Hinojosa, Cintia P.; Chabot, Aimee; Bergen, Holly; Kawamura, Mari; Steubing, Fred

    2016-01-01

    What can be done to reduce unhealthy eating among adolescents? It was hypothesized that aligning healthy eating with important and widely shared adolescent values would produce the needed motivation. A double-blind, randomized, placebo-controlled experiment with eighth graders (total n = 536) evaluated the impact of a treatment that framed healthy eating as consistent with the adolescent values of autonomy from adult control and the pursuit of social justice. Healthy eating was suggested as a way to take a stand against manipulative and unfair practices of the food industry, such as engineering junk food to make it addictive and marketing it to young children. Compared with traditional health education materials or to a non–food-related control, this treatment led eighth graders to see healthy eating as more autonomy-assertive and social justice-oriented behavior and to forgo sugary snacks and drinks in favor of healthier options a day later in an unrelated context. Public health interventions for adolescents may be more effective when they harness the motivational power of that group’s existing strongly held values. PMID:27621440

  10. Harnessing adolescent values to motivate healthier eating.

    PubMed

    Bryan, Christopher J; Yeager, David S; Hinojosa, Cintia P; Chabot, Aimee; Bergen, Holly; Kawamura, Mari; Steubing, Fred

    2016-09-27

    What can be done to reduce unhealthy eating among adolescents? It was hypothesized that aligning healthy eating with important and widely shared adolescent values would produce the needed motivation. A double-blind, randomized, placebo-controlled experiment with eighth graders (total n = 536) evaluated the impact of a treatment that framed healthy eating as consistent with the adolescent values of autonomy from adult control and the pursuit of social justice. Healthy eating was suggested as a way to take a stand against manipulative and unfair practices of the food industry, such as engineering junk food to make it addictive and marketing it to young children. Compared with traditional health education materials or to a non-food-related control, this treatment led eighth graders to see healthy eating as more autonomy-assertive and social justice-oriented behavior and to forgo sugary snacks and drinks in favor of healthier options a day later in an unrelated context. Public health interventions for adolescents may be more effective when they harness the motivational power of that group's existing strongly held values.

  11. The basement of the Mount Athos peninsula, northern Greece: insights from geochemistry and zircon ages

    NASA Astrophysics Data System (ADS)

    Himmerkus, F.; Zachariadis, P.; Reischmann, T.; Kostopoulos, D.

    2012-09-01

    The Mount Athos Peninsula is situated in the south-easternmost part of the Chalkidiki Peninsula in northern Greece. It belongs to the Serbo-Macedonian Massif (SMM), a large basement massif within the Internal Hellenides. The south-eastern part of the Mount Athos peninsula is built by fine-grained banded biotite gneisses and migmatites forming a domal structure. The southern tip of the peninsula, which also comprises Mount Athos itself, is built by limestone, marble and low-grade metamorphic rocks of the Chortiatis Unit. The northern part and the majority of the western shore of the Mount Athos peninsula are composed of highly deformed rocks belonging to a tectonic mélange termed the Athos-Volvi-Suture Zone (AVZ), which separates two major basement units: the Vertiskos Terrane in the west and the Kerdillion Unit in the east. The rock-types in this mélange range from metasediments, marbles and gneisses to amphibolites, eclogites and peridotites. The gneisses are tectonic slivers of the adjacent basement complexes. The mélange zone and the gneisses were intruded by granites (Ierissos, Ouranoupolis and Gregoriou). The Ouranoupolis intrusion obscures the contact between the mélange and the gneisses. The granites are only slightly deformed and therefore postdate the accretionary event that assembled the units and created the mélange. Pb-Pb- and U-Pb-SHRIMP-dating of igneous zircons of the gneisses and granites of the eastern Athos peninsula in conjunction with geochemical and isotopic analyses are used to put Athos into the context of a regional tectonic model. The ages form three clusters: The basement age is indicated by two samples that yielded Permo-Carboniferous U-Pb-ages of 292.6 ± 2.9 Ma and 299.4 ± 3.5 Ma. The main magmatic event of the granitoids now forming the gneiss dome is dated by Pb-Pb-ages between 140.0 ± 2.6 Ma and 155.7 ± 5.1 Ma with a mean of 144.7 ± 2.4 Ma. A within-error identical age of 146.6 ± 2.3 Ma was obtained by the U

  12. Harnessing ICT Potential: The Adoption and Analysis of ICT Systems for Enhancing the Student Learning Experience

    ERIC Educational Resources Information Center

    Dawson, Shane; Heathcote, Liz; Poole, Gary

    2010-01-01

    Purpose: This paper aims to examine how effective higher education institutions have been in harnessing the data capture mechanisms from their student information systems, learning management systems and communication tools for improving the student learning experience and informing practitioners of the achievement of specific learning outcomes.…

  13. Harnessing the power of big data: infusing the scientific method with machine learning to transform ecology

    USDA-ARS?s Scientific Manuscript database

    Most efforts to harness the power of big data for ecology and environmental sciences focus on data and metadata sharing, standardization, and accuracy. However, many scientists have not accepted the data deluge as an integral part of their research because the current scientific method is not scalab...

  14. The interstellar formation and spectra of the noble gas, proton-bound HeHHe+, HeHNe+ and HeHAr+ complexes

    NASA Astrophysics Data System (ADS)

    Stephan, Cody J.; Fortenberry, Ryan C.

    2017-07-01

    The sheer interstellar abundance of helium makes any bound molecules or complexes containing it of potential interest for astrophysical observation. This work utilizes high-level and trusted quantum chemical techniques to predict the rotational, vibrational and rovibrational traits of HeHHe+, HeHNe+ and HeHAr+. The first two are shown to be strongly bound, while HeHAr+ is shown to be more of a van der Waals complex of argonium with a helium atom. In any case, the formation of HeHHe+ through reactions of HeH+ with HeH3+ is exothermic. HeHHe+ exhibits the quintessentially bright proton-shuttle motion present in all proton-bound complexes in the 7.4 micron range making it a possible target for telescopic observation at the mid-/far-Infrared crossover point and a possible tracer for the as-of-yet unobserved helium hydride cation. Furthermore, a similar mode in HeHNe+ can be observed to the blue of this close to 6.9 microns. The brightest mode of HeHAr+ is dimmed due the reduced interaction of the helium atom with the central proton, but this fundamental frequency can be found slightly to the red of the Ar-H stretch in the astrophysically detected argonium cation.

  15. Albumin-based drug delivery: harnessing nature to cure disease.

    PubMed

    Larsen, Maja Thim; Kuhlmann, Matthias; Hvam, Michael Lykke; Howard, Kenneth A

    2016-01-01

    The effectiveness of a drug is dependent on accumulation at the site of action at therapeutic levels, however, challenges such as rapid renal clearance, degradation or non-specific accumulation requires drug delivery enabling technologies. Albumin is a natural transport protein with multiple ligand binding sites, cellular receptor engagement, and a long circulatory half-life due to interaction with the recycling neonatal Fc receptor. Exploitation of these properties promotes albumin as an attractive candidate for half-life extension and targeted intracellular delivery of drugs attached by covalent conjugation, genetic fusions, association or ligand-mediated association. This review will give an overview of albumin-based products with focus on the natural biological properties and molecular interactions that can be harnessed for the design of a next-generation drug delivery platform.

  16. Quantitative Proteome Analysis Reveals Increased Content of Basement Membrane Proteins in Arteries From Patients With Type 2 Diabetes Mellitus and Lower Levels Among Metformin Users.

    PubMed

    Preil, Simone A R; Kristensen, Lars P; Beck, Hans C; Jensen, Pia S; Nielsen, Patricia S; Steiniche, Torben; Bjørling-Poulsen, Marina; Larsen, Martin R; Hansen, Maria L; Rasmussen, Lars M

    2015-10-01

    The increased risk of cardiovascular diseases in type 2 diabetes mellitus has been extensively documented, but the origins of the association remain largely unknown. We sought to determine changes in protein expressions in arterial tissue from patients with type 2 diabetes mellitus and moreover hypothesized that metformin intake influences the protein composition. We analyzed nonatherosclerotic repair arteries gathered at coronary bypass operations from 30 patients with type 2 diabetes mellitus and from 30 age- and sex-matched nondiabetic individuals. Quantitative proteome analysis was performed by isobaric tag for relative and absolute quantitation-labeling and liquid chromatography-mass spectrometry, tandem mass spectrometry analysis on individual arterial samples. The amounts of the basement membrane components, α1-type IV collagen and α2-type IV collagen, γ1-laminin and β2-laminin, were significantly increased in patients with diabetes mellitus. Moreover, the expressions of basement membrane components and other vascular proteins were significantly lower among metformin users when compared with nonusers. Patients treated with or without metformin had similar levels of hemoglobin A1c, cholesterol, and blood pressure. In addition, quantitative histomorphometry showed increased area fractions of collagen-stainable material in tunica intima and media among patients with diabetes mellitus. The distinct accumulation of arterial basement membrane proteins in type 2 diabetes mellitus discloses a similarity between the diabetic macroangiopathy and microangiopathy and suggests a molecular explanation behind the alterations in vascular remodeling, biomechanical properties, and aneurysm formation described in diabetes mellitus. The lower amounts of basement membrane components in metformin-treated individuals are compatible with the hypothesis of direct beneficial drug effects on the matrix composition in the vasculature. © 2015 American Heart Association, Inc.

  17. Fluid Mechanics of the Vascular Basement Membrane in the Brain

    NASA Astrophysics Data System (ADS)

    Coloma, Mikhail; Hui, Jonathan; Chiarot, Paul; Huang, Peter; Carare, Roxana; McLeod, Kenneth; Schaffer, David

    2013-11-01

    Beta-amyloid is a normal product of brain metabolic function and is found within the interstitial fluid of the brain. Failure of the clearance of beta-amyloid from the aging brain leads to its accumulation within the walls of arteries and to Alzheimer's disease. The vascular basement membrane (VBM) within the walls of cerebral arteries surrounds the spirally arranged smooth muscle cells and represents an essential pathway for removal of beta-amyloid from the brain. This process fails with the stiffening of arterial walls associated with aging. In this study we hypothesize that the deformation of the VBM associated with arterial pulsations drives the interstitial fluid to drain in the direction opposite of the arterial blood flow. This hypothesis is theoretically investigated by modeling the VBM as a thin, coaxial, fluid-filled porous medium surrounding a periodically deforming cylindrical tube. Flow and boundary conditions required to achieve such a backward clearance are derived through a control volume analysis of mass, momentum, and energy.

  18. Registration of a male fertility restorer oilseed sunflower germplasm HA-R9 resistant to sunflower rust

    USDA-ARS?s Scientific Manuscript database

    The sunflower (Helianthus annuus L.) germplasm HA-R9 (Reg. No.xxx, PI 667595) was developed by the USDA-ARS, Sunflower and Plant Biology Research Unit in collaboration with the Agricultural Experiment Station of North Dakota State University and released in January, 2013. Sunflower rust (caused by P...

  19. Magnetically inferred basement structure in central Saudi Arabia

    USGS Publications Warehouse

    Johnson, P.R.; Stewart, I.C.F.

    1995-01-01

    A compilation of magnetic data acquired during the past three decades for a region in central Saudi Arabia where Precambrian basement is partly exposed on the Arabian shield and partly concealed by overlying Phanerozoic strata, shows a central sector of conspicuous N-S-trending anomalies, a heterogeneous western sector of short-wavelength, high-intensity anomalies, and an eastern sector of low- to moderate-intensity broad-wavelength anomalies. Anomalies in the western and central sectors correlate with Neoproterozoic metavolcanic, metasedimentary, and intrusive rocks of the Arabian shield and are interpreted as delineating extensions of shield-type rocks down-dip beneath Phanerozoic cover. These rocks constitute terranes making up part of a Neoproterozoic orogenic belt that underlies Northeast Africa and western Arabia and it is proposed that their magnetically indicated easternmost extent marks the concealed eastern edge of the orogenic belt in central Arabia. The flat magnetic signature of the eastern sector, not entirely accounted for as an effect of deep burial, may reflect the presence of a crustal block different in character to the terranes of the orogenic belt and, speculatively, may outline a continental block that, according to some tectonic models of the region, collided with the Neoproterozoic terranes and thereby caused their deformation and tectonic accretion.

  20. Soy protein preserves basement membrane integrity through a synergistic effect on nephrin, matrix metalloproteinase and vascular endothelial growth factor.

    PubMed

    Palanisamy, Nallasamy; Anuradha, Carani Venkataraman

    2011-01-01

    Soy protein improves renal function and prevents albuminuria in diabetic rats. This study investigates whether the renoprotective effect of soy protein is related to sustenance of basement membrane integrity. Adult male albino rats were randomized into four groups and fed one of the following semi-synthetic diets consisting of corn starch (60%) and casein (20%; CCD), fructose (60%) and casein (20%; FCD), fructose (60%) and soy protein (20%; FSD), or corn starch (60%) and soy protein (20%; CSD). Plasma chemistry and renal changes were analyzed after 60 days. FCD rats displayed metabolic derangements and renal ultrastructural changes. FSD rats showed reduction in type IV collagen, tissue inhibitor for matrix metallo-proteinase-2, vascular endothelial growth factor and tumor necrosis factor-α expression and improved matrix metallo-proteinase expression. Renal architecture was preserved in these rats. Soy protein supplementation not only improved insulin sensitivity but also markedly attenuated renal basement membrane changes in fructose diet-fed rats. These findings provide evidence in support of the use of dietary soy protein in patients with diabetic kidney disease. Copyright © 2011 S. Karger AG, Basel.