Improved methods for nightside time domain Lunar Electromagnetic Sounding

NASA Astrophysics Data System (ADS)

Fuqua-Haviland, H.; Poppe, A. R.; Fatemi, S.; Delory, G. T.; De Pater, I.

2017-12-01

Time Domain Electromagnetic (TDEM) Sounding isolates induced magnetic fields to remotely deduce material properties at depth. The first step of performing TDEM Sounding at the Moon is to fully characterize the dynamic plasma environment, and isolate geophysically induced currents from concurrently present plasma currents. The transfer function method requires a two-point measurement: an upstream reference measuring the pristine solar wind, and one downstream near the Moon. This method was last performed during Apollo assuming the induced fields on the nightside of the Moon expand as in an undisturbed vacuum within the wake cavity [1]. Here we present an approach to isolating induction and performing TDEM with any two point magnetometer measurement at or near the surface of the Moon. Our models include a plasma induction model capturing the kinetic plasma environment within the wake cavity around a conducting Moon, and a geophysical forward model capturing induction in a vacuum. The combination of these two models enable the analysis of magnetometer data within the wake cavity. Plasma hybrid models use the upstream plasma conditions and interplanetary magnetic field (IMF) to capture the wake current systems formed around the Moon. The plasma kinetic equations are solved for ion particles with electrons as a charge-neutralizing fluid. These models accurately capture the large scale lunar wake dynamics for a variety of solar wind conditions: ion density, temperature, solar wind velocity, and IMF orientation [2]. Given the 3D orientation variability coupled with the large range of conditions seen within the lunar plasma environment, we characterize the environment one case at a time. The global electromagnetic induction response of the Moon in a vacuum has been solved numerically for a variety of electrical conductivity models using the finite-element method implemented within the COMSOL software. This model solves for the geophysically induced response in vacuum to

Application and evaluation of electromagnetic methods for imaging saltwater intrusion in coastal aquifers: Seaside Groundwater Basin, California

USGS Publications Warehouse

Nenna, Vanessa; Herckenrather, Daan; Knight, Rosemary; Odlum, Nick; McPhee, Darcy

2013-01-01

Developing effective resource management strategies to limit or prevent saltwater intrusion as a result of increasing demands on coastal groundwater resources requires reliable information about the geologic structure and hydrologic state of an aquifer system. A common strategy for acquiring such information is to drill sentinel wells near the coast to monitor changes in water salinity with time. However, installation and operation of sentinel wells is costly and provides limited spatial coverage. We studied the use of noninvasive electromagnetic (EM) geophysical methods as an alternative to installation of monitoring wells for characterizing coastal aquifers. We tested the feasibility of using EM methods at a field site in northern California to identify the potential for and/or presence of hydraulic communication between an unconfined saline aquifer and a confined freshwater aquifer. One-dimensional soundings were acquired using the time-domain electromagnetic (TDEM) and audiomagnetotelluric (AMT) methods. We compared inverted resistivity models of TDEM and AMT data obtained from several inversion algorithms. We found that multiple interpretations of inverted models can be supported by the same data set, but that there were consistencies between all data sets and inversion algorithms. Results from all collected data sets suggested that EM methods are capable of reliably identifying a saltwater-saturated zone in the unconfined aquifer. Geophysical data indicated that the impermeable clay between aquifers may be more continuous than is supported by current models.

Textured digital elevation model formation from low-cost UAV LADAR/digital image data

NASA Astrophysics Data System (ADS)

Bybee, Taylor C.; Budge, Scott E.

2015-05-01

Textured digital elevation models (TDEMs) have valuable use in precision agriculture, situational awareness, and disaster response. However, scientific-quality models are expensive to obtain using conventional aircraft-based methods. The cost of creating an accurate textured terrain model can be reduced by using a low-cost (<$20k) UAV system fitted with ladar and electro-optical (EO) sensors. A texel camera fuses calibrated ladar and EO data upon simultaneous capture, creating a texel image. This eliminates the problem of fusing the data in a post-processing step and enables both 2D- and 3D-image registration techniques to be used. This paper describes formation of TDEMs using simulated data from a small UAV gathering swaths of texel images of the terrain below. Being a low-cost UAV, only a coarse knowledge of position and attitude is known, and thus both 2D- and 3D-image registration techniques must be used to register adjacent swaths of texel imagery to create a TDEM. The process of creating an aggregate texel image (a TDEM) from many smaller texel image swaths is described. The algorithm is seeded with the rough estimate of position and attitude of each capture. Details such as the required amount of texel image overlap, registration models, simulated flight patterns (level and turbulent), and texture image formation are presented. In addition, examples of such TDEMs are shown and analyzed for accuracy.

Time-domain electromagnetic tests in the Wadi Bidah District, Kingdom of Saudi Arabia

USGS Publications Warehouse

Flanigan, Vincent J.; Sadek, Hamdy; Smith, Bruce; Tippens, C.L.

1983-01-01

A time-domain electromagnetic (TDEM) method was tested in two areas of mineralization in Precambrian rocks in the Wadi Bidah district, Kingdom of Saudi Arabia. Transient-decay voltages in profile mode were measured across the Sha'ab at Tare and Rabathan prospects by use of three transmitterreceiver loop configurations. At the Sha'ab at Tare prospect all of the loop configurations indicated the mineralized zone. Analysis of the coincident loop data at Sha'ab at Tare reveals that gossanous and altered rock of i0 ohm-m resistivity extends to a depth of 35 m, where there is an unweathered, dry mineralized zone of about 1 ohm-m resistivity. The model further suggests that the rocks at a depth of 55 m and below the water table are even less resistive (0. 1 ohm-m). The TDEM method successfully discriminated conductors within from those below the weathered zone at the Rabathan prospect. Conductors below the weathered zone are identified by a lack of transient response in the early part of the transient decay curve, followed by an increasing response in the middle to late parts of the transient decay curve. Results of these limited tests suggest the potential value of integrating TDEM with other geophysical tools in the Kingdom. Recommendations are made to expand these tests into a more comprehensive program that will evaluate the TDEM potential in various geologic environments that are host to mineral deposits of diverse origin.

Application of Surface Geophysical Methods, With Emphasis on Magnetic Resonance Soundings, to Characterize the Hydrostratigraphy of the Brazos River Alluvium Aquifer, College Station, Texas, July 2006 - A Pilot Study

USGS Publications Warehouse

Shah, Sachin D.; Kress, Wade H.; Legchenko, Anatoly

2007-01-01

The U.S. Geological Survey, in cooperation with the Texas Water Development Board, used surface geophysical methods at the Texas A&M University Brazos River Hydrologic Field Research Site near College Station, Texas, in a pilot study, to characterize the hydrostratigraphic properties of the Brazos River alluvium aquifer and determine the effectiveness of the methods to aid in generating an improved ground-water availability model. Three non-invasive surface geophysical methods were used to characterize the electrical stratigraphy and hydraulic properties and to interpret the hydrostratigraphy of the Brazos River alluvium aquifer. Two methods, time-domain electromagnetic (TDEM) soundings and two-dimensional direct-current (2D-DC) resistivity imaging, were used to define the lateral and vertical extent of the Ships clay, the alluvium of the Brazos River alluvium aquifer, and the underlying Yegua Formation. Magnetic resonance sounding (MRS), a recently developed geophysical method, was used to derive estimates of the hydrologic properties including percentage water content and hydraulic conductivity. Results from the geophysics study demonstrated the usefulness of combined TDEM, 2D-DC resistivity, and MRS methods to reduce the need for additional boreholes in areas with data gaps and to provide more accurate information for ground-water availability models. Stratigraphically, the principal finding of this study is the relation between electrical resistivity and the depth and thickness of the subsurface hydrostratigraphic units at the site. TDEM data defined a three-layer electrical stratigraphy corresponding to a conductor-resistor-conductor that represents the hydrostratigraphic units - the Ships clay, the alluvium of the Brazos River alluvium aquifer, and the Yegua Formation. Sharp electrical boundaries occur at about 4 to 6 and 20 to 22 meters below land surface based on the TDEM data and define the geometry of the more resistive Brazos River alluvium aquifer

Faulting and groundwater in a desert environment: constraining hydrogeology using time-domain electromagnetic data

USGS Publications Warehouse

Bedrosian, Paul A.; Burgess, Matthew K.; Nishikawa, Tracy

2013-01-01

Within the south-western Mojave Desert, the Joshua Basin Water District is considering applying imported water into infiltration ponds in the Joshua Tree groundwater sub-basin in an attempt to artificially recharge the underlying aquifer. Scarce subsurface hydrogeological data are available near the proposed recharge site; therefore, time-domain electromagnetic (TDEM) data were collected and analysed to characterize the subsurface. TDEM soundings were acquired to estimate the depth to water on either side of the Pinto Mountain Fault, a major east-west trending strike-slip fault that transects the proposed recharge site. While TDEM is a standard technique for groundwater investigations, special care must be taken when acquiring and interpreting TDEM data in a twodimensional (2D) faulted environment. A subset of the TDEM data consistent with a layered-earth interpretation was identified through a combination of three-dimensional (3D) forward modelling and diffusion time-distance estimates. Inverse modelling indicates an offset in water table elevation of nearly 40 m across the fault. These findings imply that the fault acts as a low-permeability barrier to groundwater flow in the vicinity of the proposed recharge site. Existing production wells on the south side of the fault, together with a thick unsaturated zone and permeable near-surface deposits, suggest the southern half of the study area is suitable for artificial recharge. These results illustrate the effectiveness of targeted TDEM in support of hydrological studies in a heavily faulted desert environment where data are scarce and the cost of obtaining these data by conventional drilling techniques is prohibitive.

Electromagnetic detection of deep freshwater lenses in a hyper-arid limestone terrain

NASA Astrophysics Data System (ADS)

Young, Michael E.; Macumber, Phillip G.; Donald Watts, M.; Al-Toqy, Nasser

2004-12-01

In the hyper-arid desert of Central Oman, freshwater lenses are found lying on a regional saline water table. These lenses have developed where recharge from infrequent cyclonic rainfall has collected in shallow depressions on the Tertiary limestones of the Central Plateau and in the catchments of ancient river channels draining the Plateau. Central-loop time-domain electromagnetic (TDEM) sounding was applied as a method of reconnaissance exploration for these lenses at two sites, a shallow depression extending over an area of 60 km 2 and a wadi gorge draining a catchment of 3400 km 2. These results were subsequently tested by drilling. In the case of the shallow depression, drilling intersected a freshwater lens up to 18 m thick at a depth of 92 m. TDEM resistivity-depth inversion showed that the corresponding high resistivity zone included both the lens and overlying unsaturated rocks, and that the depth to the saline interface could be accurately predicted. Where drilling failed to intersect a lens, TDEM inversion resulted in a consistently low resistivity zone in which the water table could not be resolved. By invoking the Archie formula modified for the presence of clays, it is thought that the higher resistivity of the vadose zone observed over the lens may be explained by a reduction in the clay conductivity factor resulting from higher pore-water resistivity. In the case of the wadi gorge, low regional resistivities were also recorded over the limestones on the survey margins, and high resistivity anomalies over the freshwater lens within and extending away from the gorge. Again, TDEM was found to be useful as a reconnaissance method and for mapping the depth to the underlying saline aquifer, but not for predicting the thickness of the overlying freshwater lens.

Les sondages électromagnétiques temporels comme outil de reconnaissance du gisement phosphaté de Sidi Chennane (Maroc) : apport à la résolution d'un problème d'exploitation

NASA Astrophysics Data System (ADS)

Kchikach, Azzouz; Andrieux, Pierre; Jaffal, Mohammed; Amrhar, Mostafa; Mchichi, Mohammed; Boya, Baadi; Amaghzaz, Mbarek; Veyrieras, Thierry; Iqizou, Khadija

2006-05-01

Exploitation of the phosphatic layers in Sidi Chennane deposit (Morocco) collides frequently with problems bound to the existence, in the phosphatic series, of sterile bodies qualified as derangements. Our study shows that these bodies, masked by the Quaternary cover can be mapped using the Time-Domain ElectroMagnetic Soundings method (TDEM). It is based on the acquisition and the interpretation of a series of tests carried out above a visible derangement in an old trench of exploitation and on 2500 TDEM soundings carried out in a virgin area of the deposit. The article concerns to the analysis of the results and of the proceeding for a possible large geophysics survey. To cite this article: A. Kchikach et al., C. R. Geoscience 338 (2006).

Geophysical delineation of the freshwater/saline-water transition zone in the Barton Springs segment of the Edwards Aquifer, Travis and Hays Counties, Texas, September 2006

USGS Publications Warehouse

Payne, J.D.; Kress, W.H.; Shah, S.D.; Stefanov, J.E.; Smith, B.A.; Hunt, B.B.

2007-01-01

During September 2006, the U.S. Geological Survey, in cooperation with the Barton Springs/Edwards Aquifer Conservation District, conducted a geophysical pilot study to determine whether time-domain electromagnetic (TDEM) sounding could be used to delineate the freshwater/saline-water transition zone in the Barton Springs segment of the Edwards aquifer in Travis and Hays Counties, Texas. There was uncertainty regarding the application of TDEM sounding for this purpose because of the depth of the aquifer (200-500 feet to the top of the aquifer) and the relatively low-resistivity clayey units in the upper confining unit. Twenty-five TDEM soundings were made along four 2-3-mile-long profiles in a study area overlying the transition zone near the Travis-Hays County boundary. The soundings yield measurements of subsurface electrical resistivity, the variations in which were correlated with hydrogeologic and stratigraphic units, and then with dissolved solids concentrations in the aquifer. Geonics Protem 47 and 57 systems with 492-foot and 328-foot transmitter-loop sizes were used to collect the TDEM soundings. A smooth model (vertical delineation of calculated apparent resistivity that represents an estimate [non-unique] of the true resistivity) for each sounding site was created using an iterative software program for inverse modeling. The effectiveness of using TDEM soundings to delineate the transition zone was indicated by comparing the distribution of resistivity in the aquifer with the distribution of dissolved solids concentrations in the aquifer along the profiles. TDEM sounding data show that, in general, the Edwards aquifer in the study area is characterized by a sharp change in resistivity from west to east. The western part of the Edwards aquifer in the study area shows higher resistivity than the eastern part. The higher resistivity regions correspond to lower dissolved solids concentrations (freshwater), and the lower resistivity regions correspond to

Time-domain electromagnetic soundings collected in Dawson County, Nebraska, 2007-09

USGS Publications Warehouse

Payne, Jason; Teeple, Andrew

2011-01-01

Between April 2007 and November 2009, the U.S. Geological Survey, in cooperation with the Central Platte Natural Resources District, collected time-domain electro-magnetic (TDEM) soundings at 14 locations in Dawson County, Nebraska. The TDEM soundings provide information pertaining to the hydrogeology at each of 23 sites at the 14 locations; 30 TDEM surface geophysical soundings were collected at the 14 locations to develop smooth and layered-earth resistivity models of the subsurface at each site. The soundings yield estimates of subsurface electrical resistivity; variations in subsurface electrical resistivity can be correlated with hydrogeologic and stratigraphic units. Results from each sounding were used to calculate resistivity to depths of approximately 90-130 meters (depending on loop size) below the land surface. Geonics Protem 47 and 57 systems, as well as the Alpha Geoscience TerraTEM, were used to collect the TDEM soundings (voltage data from which resistivity is calculated). For each sounding, voltage data were averaged and evaluated statistically before inversion (inverse modeling). Inverse modeling is the process of creating an estimate of the true distribution of subsurface resistivity from the mea-sured apparent resistivity obtained from TDEM soundings. Smooth and layered-earth models were generated for each sounding. A smooth model is a vertical delineation of calculated apparent resistivity that represents a non-unique estimate of the true resistivity. Ridge regression (Interpex Limited, 1996) was used by the inversion software in a series of iterations to create a smooth model consisting of 24-30 layers for each sounding site. Layered-earth models were then generated based on results of smooth modeling. The layered-earth models are simplified (generally 1 to 6 layers) to represent geologic units with depth. Throughout the area, the layered-earth models range from 2 to 4 layers, depending on observed inflections in the raw data and smooth model

Mars SubsurfAce Sounding by Time-Domain Electromagnetic MeasuRements

NASA Astrophysics Data System (ADS)

Tacconi, G.; Minna, L.; Pagnan, S.; Tacconi, M.

1999-09-01

MASTER (Mars subsurfAce Sounding by Time-domain Electromagnetic measuRements) is an experimental project proposed to fly aboard the Italian Drill (DEEDRI) payload for the Mars Surveyor Program 2003. MASTER will offer the scientific community the first opportunity to scan Mars subsurface structure by means of the technique employing time-domain electromagnetic measurements TDEM. Up today proposed experiments for scanning the Martian subsurface have focused on exploring the crust of the planet Mars up to few meters, while MASTER will explore electrical structures and related soil characteristics and processes at depths up to hundreds meters at least. TDEM represents an active remote sensing system and will be used likely a ULF/ELF/VLF ``radar." If a certain volumetric zone has different electrical conductivity, the current in the sample will vary generating a secondary scattered electromagnetic field containing the information about the explored volume. The volumetric mean value of the conductivity will be estimated according to the implicit near field e.m. propagation conditions, considering the skin depth (d) and the apparent resistivity (ra) as the most representative and critical parameters. As any active remotely sensed measurements the TDEM system behaves like a ``bistatic" communication channel and is mandatory to investigate the characteristics of the background noise at the receiver site. The MASTER system, can operate also as a passive listening device of the possible electromagnetic background noise on the Mars surface at ULF/ELF/VLF bands. Present paper will describe in details the application of the TDEM method as well as the approaches to the detection and estimation of the e.m. BGN on Mars surface, in terms of man made, natural BGN and intrinsic noise of the sensors and electronic systems. The electromagnetic background noise detection/estimation represents by itself a no cost experiment and the first experiment of this type on Mars.

Hydrostratigraphic interpretation of test-hole and surface geophysical data, Elkhorn and Loup River Basins, Nebraska, 2008 to 2011

USGS Publications Warehouse

Hobza, Christopher M.; Bedrosian, Paul A.; Bloss, Benjamin R.

2012-01-01

The Elkhorn-Loup Model (ELM) was begun in 2006 to understand the effect of various groundwater-management scenarios on surface-water resources. During phase one of the ELM study, a lack of subsurface geological information was identified as a data gap. Test holes drilled to the base of the aquifer in the ELM study area are spaced as much as 25 miles apart, especially in areas of the western Sand Hills. Given the variable character of the hydrostratigraphic units that compose the High Plains aquifer system, substantial variation in aquifer thickness and characteristics can exist between test holes. To improve the hydrogeologic understanding of the ELM study area, the U.S. Geological Survey, in cooperation with the Nebraska Department of Natural Resources, multiple Natural Resources Districts participating in the ELM study, and the University of Nebraska-Lincoln Conservation and Survey Division, described the subsurface lithology at six test holes drilled in 2010 and concurrently collected borehole geophysical data to identify the base of the High Plains aquifer system. A total of 124 time-domain electromagnetic (TDEM) soundings of resistivity were collected at and between selected test-hole locations during 2008-11 as a quick, non-invasive means of identifying the base of the High Plains aquifer system. Test-hole drilling and geophysical logging indicated the base-of-aquifer elevation was less variable in the central ELM area than in previously reported results from the western part of the ELM study area, where deeper paleochannels were eroded into the Brule Formation. In total, more than 435 test holes were examined and compared with the modeled-TDEM soundings. Even where present, individual stratigraphic units could not always be identified in modeled-TDEM sounding results if sufficient resistivity contrast was not evident; however, in general, the base of aquifer [top of the aquifer confining unit (ACU)] is one of the best-resolved results from the TDEM

Effector T-cells are expanded in systemic lupus erythematosus patients with high disease activity and damage indexes.

PubMed

Piantoni, S; Regola, F; Zanola, A; Andreoli, L; Dall'Ara, F; Tincani, A; Airo', P

2018-01-01

Background and objectives T-cell activation may be one of the pathogenic mechanisms of systemic lupus erythematosus (SLE). After repeated antigenic stimulation, T-cells undergo different modifications, leading to the differentiation into effector memory T-cells (CCR7-CD45RA-) and terminally differentiated effector memory (TDEM) T-cells (CCR7-CD45RA+). Similarly, down-modulation of CD28 may lead to the expansion of the CD28- T-cells, a subpopulation with peculiar effector activities. The aim of this study was the characterization of T-cell phenotype in a cohort of patients with SLE according to disease activity and damage index. Materials and methods Phenotypic analysis of peripheral blood T lymphocytes of 51 SLE patients and 21 healthy controls was done by flow-cytometry. SLE disease activity was evaluated by SLE Disease Activity Index-2000 (SLEDAI-2K) and damage by the Systemic Lupus International Collaborating Clinics/American College of Rheumatology damage index (SDI). The variations between different groups were evaluated by Mann-Whitney test. Bonferroni correction was applied to adjust for multiple comparisons ( p adj ). Spearman rank test was used to evaluate the correlations between quantitative variables. Results CD4+ lymphopenia was found among SLE patients. Patients showed a trend for a higher percentage of TDEM among the CD4+ T-cell subpopulation in comparison with healthy controls ( p = .04). SLE patients were divided into two groups according to disease activity: patients with SLEDAI-2K ≥ 6 ( n = 13) had a higher percentage of circulating CD4+ T-cells with CD28- phenotype ( p adj  = .005) as well as those with an effector memory ( p adj  = .004) and TDEM ( p adj  = .002) phenotype and a trend of decrease of regulatory T-cells (TREGs) ( p = .02), in comparison with patients with low disease activity ( n = 38). Patients with damage (SDI ≥ 1) tended to show an expansion of TDEM among CD4+ T-cells as compared with

Verifying occulter deployment tolerances as part of NASA's technology development for exoplanet missions

NASA Astrophysics Data System (ADS)

Kasdin, N. J.; Lisman, D.; Shaklan, S.; Thomson, M.; Webb, D.; Cady, E.; Marks, G. W.; Lo, A.

2013-09-01

An external occulter is a satellite employing a large screen, or starshade, that flies in formation with a spaceborne telescope to provide the starlight suppression needed for detecting and characterizing exoplanets. Among the advantages of using an occulter are the broadband allowed for characterization and the removal of light before entering the observatory, greatly relaxing the requirements on the telescope and instrument. In support of NASA's Exoplanet Exploration Program and the Technology Development for Exoplanet Missions (TDEM), we recently completed a 2 year study of the manufacturability and metrology of starshade petals. In this paper we review the results of that successful first TDEM which demonstrated an occulter petal could be built and measured to an accuracy consistent with close to 10-10 contrast. We then present the results of our second TDEM to demonstrate the next critical technology milestone: precision deployment of the central truss and petals to the necessary accuracy. We show the deployment of an existing deployable truss outfitted with four sub-scale petals and a custom designed central hub.

Unravelling aquifer-wetland interaction using CSAMT and gravity methods: the Mollina-Camorra aquifer and the Fuente de Piedra playa-lake, southern Spain

NASA Astrophysics Data System (ADS)

Pedrera, A.; Martos-Rosillo, S.; Galindo-Zaldívar, J.; Rodríguez-Rodríguez, M.; Benavente, J.; Martín-Rodríguez, J. F.; Zúñiga-López, M. I.

2016-06-01

The hydrological regime of Fuente de Piedra playa-lake (Málaga, southern Spain) has been significantly affected by the intensive exploitation of groundwater in the area. The playa-lake is situated above clays, marls, and gypsum, and under unaltered conditions received surface-subsurface runoff within the watershed as well as groundwater discharge from two carbonate aquifers. We have analyzed the structure of the main one, the Mollina-Camorra carbonate aquifer, by combining controlled source audio magnetotellurics (CSAMT), gravity prospecting, and time-domain electromagnetic (TDEM) soundings. This geophysical information, together with new structural and hydrogeological data, was gathered to develop a new conceptual hydrogeological model. This model allows the hydrological linkage of the carbonate aquifer with the playa-lake system to be established. Moreover, the intensive exploitation in the carbonate aquifer, even outside the watershed of the playa-lake, has affected the hydrological regime of the system. This multidisciplinary work demonstrates the potential of geophysical methods for understanding wetland-aquifer interaction, having important groundwater management implications.

Verify Occulter Deployment Tolerances as Part of NASA's Technology Development for Exoplanet Missions

NASA Astrophysics Data System (ADS)

Kasdin, N. J.; Shaklan, S.; Lisman, D.; Thomson, M.; Webb, D.; Cady, E.; Marks, G. W.; Lo, A.

2013-01-01

In support of NASA's Exoplanet Exploration Program and the Technology Development for Exoplanet Missions (TDEM), we recently completed a 2 year study of the manufacturability and metrology of starshade petals. An external occult is a satellite employing a large screen, or starshade, that flies in formation with a spaceborne telescope to provide the starlight suppression needed for detecting and characterizing exoplanets. Among the advantages of using an occulter are the broadband allowed for characterization and the removal of light before entering the observatory, greatly relaxing the requirements on the telescope and instrument. This poster presents the results of our successful first TDEM that demonstrated an occulter petal could be built and measured to an accuracy consistent with close to 10^-10 contrast. We also present the progress in our second TDEM to demonstrate the next critical technology milestone: precision deployment of the central truss and petals to the necessary accuracy. We have completed manufacture of four sub-scale petals and a central hub to fit with an existing deployable truss. We show the plans for repeated stow and deploy tests of the assembly and the metrology to confirm that each deploy repeatably meets the absolute positioning requirements of the petals (better than 1.0 mm).

Testing Starshade Manufacturing and Deployment Through NASA's Technology Development for Exoplanet Missions Program

NASA Astrophysics Data System (ADS)

Kasdin, N. J.; Shaklan, S.; Lisman, D.; Thomson, M.; Cady, E.; Lo, A.; Macintosh, B.

2014-01-01

An external occulter is a satellite employing a large screen, or starshade, that flies in formation with a spaceborne telescope to provide the starlight suppression needed for detecting and characterizing exoplanets. Among the advantages of using an occulter are the broadband allowed for characterization and the removal of light before entering the observatory, greatly relaxing the requirements on the telescope and instrument. In this poster we report on the results of our two Technology Development for Exoplanet Missions (TDEM) studies. In the first we examined the manufacturability and metrology of starshade petals, successfully constructing a full size petal from flight like materials and showing through precise edge shape measurements that an occulter made with petals consistent with the measured accuracy would achieve close to 10^-10 contrast. Our second TDEM tested the deployment precision of a roughly half-scale starshade. We demonstrated the deployment of an existing deployable truss outfitted with four sub-scale petals and a custom designed central hub. We showed that the system can be deployed multiple times with a repeatable positioning accuracy of the petals better than the requirement of 1.0 mm. The combined results of these two TDEM projects has significantly advanced the readiness level of occulter technology and moved the community closer to a realizable mission.

Application of frequency- and time-domain electromagnetic surveys to characterize hydrostratigraphy and landfill construction at the Amargosa Desert Research Site, Beatty, Nevada

USGS Publications Warehouse

White, Eric A.; Day-Lewis, Frederick D.; Johnson, Carole D.; Lane, John W.

2016-01-01

In 2014 and 2015, the U.S. Geological Survey (USGS), conducted frequency-domain electromagnetic (FDEM) surveys at the USGS Amargosa Desert Research Site (ADRS), approximately 17 kilometers (km) south of Beatty, Nevada. The FDEM surveys were conducted within and adjacent to a closed low-level radioactive waste disposal site located at the ADRS. FDEM surveys were conducted on a grid of north-south and east-west profiles to assess the locations and boundaries of historically recorded waste-disposal trenches. In 2015, the USGS conducted time-domain (TDEM) soundings along a profile adjacent to the disposal site (landfill) in cooperation with the U.S. Environmental Protection Agency (USEPA), to assess the thickness and characteristics of the underlying deep unsaturated zone, and the hydrostratigraphy of the underlying saturated zone.FDEM survey results indicate the general location and extent of the waste-disposal trenches and reveal potential differences in material properties and the type and concentration of waste in several areas of the landfill. The TDEM surveys provide information on the underlying hydrostratigraphy and characteristics of the unsaturated zone that inform the site conceptual model and support an improved understanding of the hydrostratigraphic framework. Additional work is needed to interpret the TDEM results in the context of the local and regional structural geology.

Starshades for Exoplanet Imaging and Characterization

NASA Astrophysics Data System (ADS)

Kasdin, N. J.; Vanderbei, R. J.; Shaklan, S.; Lisman, D.; Thomson, M.; Cady, E.; Macintosh, B.; Sirbu, D.; Lo, A.

2014-01-01

An external occulter is a satellite employing a large screen, or starshade, that flies in formation with a spaceborne telescope to provide the starlight suppression needed for detecting and characterizing exoplanets. Among the advantages of using an occulter are the broadband allowed for characterization and the removal of light before entering the observatory, greatly relaxing the requirements on the telescope and instrument. In this presentation I will explain how star shades achieve high contrast through precise design and control of their shape and how we develop an error budget to establish requirements on the manufacturing and control. Raising the technology readiness level of starshades requires a sequence of activities to verify approaches to manufacturing, deployment, test, and analysis. The SAT-TDEM program has been instrumental in raising the readiness level of the most critical technology. In particular, I will show the results of our first TDEM in 2010-2012 that verified a full scale petal could be built and measured to the needed accuracy for 10 orders of magnitude of contrast. Our second TDEM in 2012-2014 verified that a starshade could be deployed and the petals could be placed to the required position to better than 1 mm. Finally, laboratory experiments have verified the optical modeling used to predict starshade performance to better than 1e-10.

An Integrated Hydrogeologic and Geophysical Investigation to Characterize the Hydrostratigraphy of the Edwards Aquifer in an Area of Northeastern Bexar County, Texas

USGS Publications Warehouse

Shah, Sachin D.; Smith, Bruce D.; Clark, Allan K.; Payne, Jason

2008-01-01

In August 2007, the U.S. Geological Survey, in cooperation with the San Antonio Water System, did a hydrogeologic and geophysical investigation to characterize the hydrostratigraphy (hydrostratigraphic zones) and also the hydrogeologic features (karst features such as sinkholes and caves) of the Edwards aquifer in a 16-square-kilometer area of northeastern Bexar County, Texas, undergoing urban development. Existing hydrostratigraphic information, enhanced by local-scale geologic mapping in the area, and surface geophysics were used to associate ranges of electrical resistivities obtained from capacitively coupled (CC) resistivity surveys, frequency-domain electromagnetic (FDEM) surveys, time-domain electromagnetic (TDEM) soundings, and two-dimensional direct-current (2D-DC) resistivity surveys with each of seven hydrostratigraphic zones (equivalent to members of the Kainer and Person Formations) of the Edwards aquifer. The principal finding of this investigation is the relation between electrical resistivity and the contacts between the hydrostratigraphic zones of the Edwards aquifer and the underlying Trinity aquifer in the area. In general, the TDEM data indicate a two-layer model in which an electrical conductor underlies an electrical resistor, which is consistent with the Trinity aquifer (conductor) underlying the Edwards aquifer (resistor). TDEM data also show the plane of Bat Cave fault, a well-known fault in the area, to be associated with a local, nearly vertical zone of low resistivity that provides evidence, although not definitive, for Bat Cave fault functioning as a flow barrier, at least locally. In general, the CC resistivity, FDEM survey, and 2D-DC resistivity survey data show a sharp electrical contrast from north to south, changing from high resistivity to low resistivity across Bat Cave fault as well as possible karst features in the study area. Interpreted karst features that show relatively low resistivity within a relatively high

The Effects of Topography on Time Domain Controlled-Source Electromagnetic Data as it Applies to Impact Crater Sites

NASA Astrophysics Data System (ADS)

Hickey, M. S.

2008-05-01

Controlled-source electromagnetic geophysical methods provide a noninvasive means of characterizing subsurface structure. In order to properly model the geologic subsurface with a controlled-source time domain electromagnetic (TDEM) system in an extreme topographic environment we must first see the effects of topography on the forward model data. I run simulations using the Texas A&M University (TAMU) finite element (FEM) code in which I include true 3D topography. From these models we see the limits of how much topography we can include before our forward model can no longer give us accurate data output. The simulations are based on a model of a geologic half space with no cultural noise and focus on topography changes associated with impact crater sites, such as crater rims and central uplift. Several topographical variations of the model are run but the main constant is that there is only a small conductivity change on the range of 10-1 s/m between the host medium and the geologic body within. Asking the following questions will guide us through determining the limits of our code: What is the maximum step we can have before we see fringe effects in our data? At what location relative to the body does the topography cause the most effect? After we know the limits of the code we can develop new methods to increase the limits that will allow us to better image the subsurface using TDEM in extreme topography.

Shallow subsurface imaging of the Piano di Pezza active normal fault (central Italy) by high-resolution refraction and electrical resistivity tomography coupled with time domain electromagnetic data

NASA Astrophysics Data System (ADS)

Villani, Fabio; Tulliani, Valerio; Fierro, Elisa; Sapia, Vincenzo; Civico, Riccardo

2015-04-01

The Piano di Pezza fault is the north-westernmost segment of the >20 km long Ovindoli-Pezza active normal fault-system (central Italy). Although existing paleoseismic data document high vertical Holocene slip rates (~1 mm/yr) and a remarkable seismogenic potential of this fault, its subsurface setting and Pleistocene cumulative displacement are still poorly known. We investigated for the first time by means of high-resolution seismic and electrical resistivity tomography coupled with time domain electromagnetic (TDEM) measurements the shallow subsurface of a key section of the Piano di Pezza fault. Our surveys cross a ~5 m-high fault scarp that was generated by repeated surface-rupturing earthquakes displacing some Late Holocene alluvial fans. We provide 2-D Vp and resistivity images which clearly show significant details of the fault structure and the geometry of the shallow basin infill material down to 50 m depth. We can estimate the dip (~50°) and the Holocene vertical displacement of the master fault (~10 m). We also recognize in the hangingwall some low-velocity/low-resistivity regions that we relate to packages of colluvial wedges derived from scarp degradation, which may represent the record of several paleo-earthquakes older than the Late Holocene events previously recognized by paleoseismic trenching. Conversely, due to the limited investigation depth of seismic and electrical tomography, the estimation of the cumulative amount of Pleistocene throw is hampered. Therefore, to increase the depth of investigation, we performed 7 TDEM measurements along the electrical profile using a 50 m loop size both in central and offset configuration. The recovered 1-D resistivity models show a good match with 2-D resistivity images in the near surface. Moreover, TDEM inversion results indicate that in the hangingwall, ~200 m away from the surface fault trace, the carbonate pre-Quaternary basement may be found at ~90-100 m depth. The combined approach of electrical and

Low-Frequency Electromagnetic Exploration for Groundwater on Mars

NASA Technical Reports Server (NTRS)

Grimm, Robert E.

2002-01-01

Water with even a small amount of dissolved solids has an electrical conductivity orders of magnitude higher than dry rock and is therefore a near-ideal exploration target on Mars for low frequency, diffusive electromagnetic methods. Models of the temperature- and frequency-dependent electrical properties of rock-ice-water mixtures are used to predict the electromagnetic response of the Martian subsurface. Detection of ice is difficult unless it is massively segregated. In contrast, liquid water profoundly affects soundings, and even a small amount of adsorbed water in the cryosphere can be detected. Subcryospheric water is readily distinguishable at frequencies as low as 100 Hz for fresh water to 10 mHz for brines. These responses can be measured using either natural or artificial sources. Ultra low frequency signals from solar wind and diurnal-heating perturbations of the ionosphere are likely, and disturbances of regional crustal magnetic fields may also be observable. Spherics, or extremely to very low frequency signals from lightning discharge, would provide optimal soundings; however, lightning may be the least likely of the possible natural sources. Among the active techniques, only the time-domain electromagnetic (TDEM) method can accommodate a closely spaced transmitter and receiver and sound to depths of hundreds of meters or more. A ground- or aircraft-based TDEM system of several kilograms can detect water to a depth of several hundred meters, and a system of tens of kilograms featuring a large, fixed, rover- or ballistically deployed loop can detect water to several kilometers depth.

Hydrostratigraphic interpretation of test-hole and geophysical data, Upper Loup River Basin, Nebraska, 2008-10

USGS Publications Warehouse

Hobza, Christopher M.; Asch, Theodore H.; Bedrosian, Paul A.

2011-01-01

Test-hole drilling has indicated greater variation in the base-of-aquifer elevation in the western part of the upper Loup study area than in the eastern part reflecting a number of deep paleovalleys incised into the Brule Formation of the White River Group. TDEM measurements within the upper Loup study area were shown to be effective as virtual boreholes in mapping out the base of the aquifer. TDEM estimates of the base of aquifer were in good accordance with existing test-hole data and were able to improve the interpreted elevation and topology of the base of the aquifer. In 2010, AMT data were collected along a profile, approximately 12 miles (19 kilometers) in length, along Whitman Road, in Grant and Cherry Counties. The AMT results along Whitman Road indicated substantial variability in the elevation of the base of the High Plains aquifer and in the distribution of highly permeable zones within the aquifer.

Research and Development of External Occultor Technology for the Direct Observation of Extrasolar Planetary Systems : JPL Starshades Project

NASA Technical Reports Server (NTRS)

Franz, Herbert; Stadeler, Mehnert

2012-01-01

Our group conducted work during the Summer of 2012 assembling and developing JPL's Starshades Project under the Technology Development for Exoplanet Missions(TDEM) initiative created by NASA, specifically TDEM stage 2. The goal of the work conducted at JPL by our group was to construct four occultor petals, the main optical components of the Starshade, for the analysis of joint deployment characteristics and of mechanical strain. A Starshade is an optical structure measuring approximately 30 meters in diameter that uses the effects of light diffraction off sheer edges, light scattering, and negative interference between waves to negate all on-axis light in a telescope's image, providing very high contrast that allows planets orbiting a target star to be observed. We completed our engineering goals in the time span of 10 weeks, during which the assembly processes of manufacture, alignment, and structural bonding took place. The Starshade technology and construction process is further discussed in the body of this paper.

Mapping subtrappean sediments and delineating structure with the aid of heliborne time domain electromagnetics: Case study from Kaladgi Basin, Karnataka

NASA Astrophysics Data System (ADS)

Sridhar, M.; Markandeyulu, A.; Chaturvedi, A. K.

2017-01-01

Mapping of subtrappean sediments is a complex geological problem attempted by many interpreters applying different geophysical techniques. Variations in thickness and resistivity of traps and underlying sediments, respectively, results in considerable uncertainty in the interpretation of geophysical data. It is proposed that the transient electromagnetic technique is an effective geophysical tool for delineation of the sub-trappean sediments, due to marked resistivity contrast between the Deccan trap, and underlying sediments and/or basement. The northern margin of the Kaladgi basin is covered under trap. A heliborne time domain electromagnetic survey was conducted to demarcate the basin extent and map the sub-trappean sediments. Conductivity depth transformations were used to map the interface between conductive trap and resistive 'basement'. Two resistivity contrast boundaries are picked: the first corresponds to the bottom of the shallow conductive unit interpreted as the base of the Deccan Volcanics and the second - picked at the base of a deeper subsurface conductive zone - is interpreted as the weathered paleo-surface of the crystalline basement. This second boundary can only be seen in areas where the volcanics are thin or absent, suggesting that the volcanics are masking the EM signal preventing deeper penetration. An interesting feature, which shows prominently in the EM data but less clearly imaged in the magnetic data, is observed in the vicinity of Mudhol. The surface geology interpreted from satellite imagery show Deccan trap cover around Mudhol. Modelling of TDEM data suggest the presence of synclinal basin structure. The depth of penetration of the heliborne TDEM data is estimated to be approximately 350 m for the study area. This suggests that heliborne TDEM could penetrate significant thicknesses of conductive Deccan trap cover to delineate structure below in the Bagalkot Group.

A New Temperature Determination Using the Fe XVII Emission of Capella

NASA Astrophysics Data System (ADS)

Beiersdorfer, P.; Gu, M. F.; Lepson, J.; Desai, P.

2011-12-01

Typically, the most reliable way to spectroscopically determine the electron temperature is to measure the strength of dielectronic recombination (DR) satellite lines relative to the associated resonance line, IDR/ Ir, as this ratio varies steeply with temperature and does not require assumptions associated with the calculations of ionization equilibria. We have applied this method to the Fe XVII lines, which are very bright in the spectrum of Capella observed with high resolution with Chandra's High Energy Transmission Grating Spectrometer. In particular, we have determined the intensity of the dielectronic satellite lines next to the Fe XVII 2p-3d resonance line, commonly denoted 3C. The atomic data needed to do this are supplied by the Flexible Atomic Code. The temperature, TDR, we have derived from this method is somewhat lower than TDEM, derived from the differential emission measure for Fe XVII. We show that the precision of this method is very high, and we discuss the its limitations.

Assessing different airborne EM systems for delivering information on aquifer geometry and character: A case study from the Musgrave Province South Australia

NASA Astrophysics Data System (ADS)

Munday, T. J.; Ley-Cooper, A. Y.

2012-12-01

When developing their pre-competitive data bases in support of the minerals industry, State and Federal Government agencies in Australia are now looking at the conjunctive use of airborne geophysics. This is particularly so for AEM data sets, which are now being acquired to promote exploration. This reflects a recognition that in the arid regions of Australia development of a given mineral deposit will, in part, be determined by the availability of water to support mining and mineral processing. An emerging trend, linked to the availability of new data processing procedures, sees AEM data now being actively employed for a combination of applications linked to minerals exploration including geological mapping, aquifer characterization and groundwater assessment. New surveys are being commissioned with attention being given as to whether AEM systems are capable of resolving the complexity of aquifer systems. In addition to new surveys, historical AEM data sets acquired to target potential mineralization are being re-processed for groundwater related applications. As part of the South Australian Goyder FLOWS project, regional and local scale AEM data sets are being examined to develop hydrogeological conceptual models in the remote Musgrave Province in the States north. The work has required the re-processing of historical data, including those acquired by TEMPEST, HoisTEM and VTEM. More recently, the project also acquired co-incident data from several new AEM systems, including the new SkyTEM508 (a helicopter TDEM system) and the SPECTREM2000 (a fixed wing TDEM system). Their acquisition aims to inform State agencies about options for acquiring further pre-competitive AEM data to support mineral exploration whilst also addressing groundwater resource requirements for the region. In this paper we examine the results from a comparative study of these systems for defining the variability of aquifers that are expected to provide the main source of groundwater for any

The MUTENAGE Project (MUsical Tools for ENhancing the Awareness of Global Emergencies)

NASA Astrophysics Data System (ADS)

Menghini, Antonio; Pontani, Stefano; Sapia, Vincenzo; Lanza, Tiziana

2017-04-01

Music can be a powerful device for raising awareness about environmental issues. Following the trend, we are organizing a project to specifically address climatic and environmental emergencies. To this aim, we use the transformation of geophysical data into musical notes, according to the procedure (EMusic) defined by Menghini and Pontani (2016). We claim that it is possible to compose musical tracks describing faithfully the geological and environmental setting of various sites, which we choose by considering five main topics: 1) Pollution of aquifers; 2) Seawater intrusion along the coastlines; 3) Seismic risk; 4) Drought; 5) Permafrost melting; The TDEM method (Time Domain Electromagnetics) shows an excellent diagnostic feature for each of these environmental emergencies. It is not surprising that the technical-scientific community widely acquire TDEM data since many years as the variations of the recorded signal (voltage) duly reflect the modifications induced on the Earth system. Through the sonification process, we can associate well-defined musical "footprints" to these geophysical variations. Then, we have an extraordinary didactic-popular tool that we can use to communicate and sensitize people and students of every age and grade about the impact of climatic-environmental changes. In this occasion, we present, among others, the example of the musical effect of seawater intrusion that is well marked by the progressive increase of the pitches when approaching the coastline. In many cases, the relationship between geophysical response and high environmental risk is straight: for instance, pollutants, like leachate or polluted groundwater, can produce high voltage responses and/or similar high voltage signals can be produced by soils affected by permafrost melting. Nevertheless, there are situations in which the diagnostic feature of TDEM is fair, however, even if the data interpretation is less immediate, so that it requires an accurate processing and

P-Them Response for Geologically Active and Non-Active Areas

NASA Astrophysics Data System (ADS)

Vetrov, A.

2011-12-01

Time Domain Electromagnetic air-borne systems are widely used in geological exploration for minerals associated with conductive rocks, underground water resources and geological underground mapping. The newly designed P-THEM system has been test-flown at the Reid Mahaffy geological test site in Northern Ontario, Canada; and then over an area near Newmarket, north of Toronto. While the flight in Reid Mahaffy was made to verify real characteristics of the system: stability and repeatability of results, the flight over the Newmarket area was made to verify correct operation of the EM system with a magnetometer and gamma-ray spectrometer. Interesting and significant response of the TDEM observations to geological, agricultural and engineering objects were observed during the test flights. These results demonstrate a possibility of TDEM method for mineral research and environmental tasks. The Reid Mahaffy Test Site is located in the Abitibi Subprovince, immediately east of the Mattagami River Fault in Ontario, Canada. The test site was created in 1999 by the Ontario Geological Survey, initially to enable various airborne geophysical systems to demonstrate their basic performance capabilities. The general geology of the site contains known overburden thickness based on almost 50 diamond drill holes, with geological logs available for these. The survey flights over Reid Mahaffy test site were performed in April 2010. The altitude and direction tests were flown on three lines over the test survey area. The response of early times represents overburden and correlates with its known thickness. The conductive body appears on later time channels and remains detectable over noise level. The electrical inversion of the results allows distinguishing a structure of several vertical conductor slices, forming the conductive body. The Newmarket area selected for tests in June 2010 is a highly developed urban zone in the Greater Toronto Area, Ontario, Canada. Geologically, the area is

The Naiades: A Mars Scout Proposal for Electromagnetic and Seismic Groundwater Exploration

NASA Astrophysics Data System (ADS)

Grimm, R. E.

2002-12-01

Detection of subsurface, liquid water is an overarching objective of the Mars Exploration Program (MEP) because of its impacts on life, climate, geology, and preparation for human exploration. Although planned orbital radars seek to map subsurface water, methods with more robust depth-penetration, discrimination, and characterization capabilities are necessary to "ground truth" any results from such radars. Low-frequency electromagnetic (EM) methods exploit induction rather than wave propagation and are sensitive to electrical conductivity rather than dielectric constant. Groundwater on Mars will likely be saline and therefore will present a near-ideal EM target, especially beneath very dry overburden. The Naiades Mars Scout - named for the Greek mythological nymphs of springs, rivers, lakes, and fountains - comprise twin Landers directed to a high-priority region for groundwater investigation. Broadband measurements of natural EM fields will be used for passive magnetotelluric, wave-tilt, and geomagnetic-depth soundings. Active, time-domain electromagnetic (TDEM) soundings will supplement natural sources (lightning?) above ~1 Hz. The two Landers are positioned within several tens of kilometers of each other so that remote references can improve natural-source data quality; useful results can, however, be acquired by a single Lander. The expected depth of exploration of the TDEM is several hundred meters or more, sufficient to determine whether putative groundwater near "gullies" is still extant. Low-frequency natural signals from the solar wind, ionosphere, and possibly crustal magnetospheres will enable passive soundings to 10 km or greater, sufficient to detect and characterize deep, stable groundwater. Additional mission objectives include detection of ground ice, characterization of natural EM fields, measurement of electrical properties of the atmosphere, dust, soil, and interior, constraints on planetary heat flow (from the thickness of the cryosphere

Characterization by electrical and electromagnetic geophysical methods of the shallow hydrogeological system at Hebron (West Bank, Palestine) in a semi-arid zone

NASA Astrophysics Data System (ADS)

Sirhan, Asal; Hamidi, Mohammad O.

2012-09-01

Multi-electrode geo-electrical and transient electromagnetic surveys were carried out to characterize the nature of the subsurface infiltration zones (5 to 20 m) related to a series of groundwater outlets, and to reveal the geometry of the different aquifers at Bani-Naim, in the south-eastern foothills of the Hebron area, West Bank, Palestine. The purpose of the surveys was to understand the link between water storage/transfer and the characteristics of the geological formations. The strata in this semi-arid region are composed of alternate layers of chalky limestone, hard limestone, marl and chalk. A total of 30 ERT and 15 TDEM were conducted at Bani Naim-Jahir and Bani Naim-Birein. A correlation between the results indicates various infiltration pathways: fractures, feature heterogeneities, and porous chalk. The local heterogeneity on the eastern side were the major pathways for the water infiltration, whereas the thick marl layer underneath acts as a natural impermeable barrier preventing water from infiltrating deeper. A combination of the different geophysical results identified conductive features that correspond to the infiltration zones supplying the dug wells with water. Furthermore, it was established that the fractured chalk and porous chalky limestone act as an aquifer. A three-dimensional visualization of the resistivity allowed a useful reconstruction of the shallow hydrogeological system. Consequently, these studies contribute to regional sustainable development projects in this semi-arid region.

Use of a time-domain electromagnetic method with geochemical tracers to explore the salinity anomalies in a small coastal aquifer in north-eastern Tunisia

NASA Astrophysics Data System (ADS)

Chekirbane, Anis; Tsujimura, Maki; Kawachi, Atsushi; Lachaal, Fethi; Isoda, Hiroko; Tarhouni, Jamila

2014-12-01

The study area is a small coastal plain in north-eastern Tunisia. It is drained by an ephemeral stream network and is subject to several pollutant discharges such as oilfield brine coming from a neighboring oil company and wastewater from Somâa city, located in the upstream of the plain. Furthermore, a hydraulic head near the coastal part of the aquifer is below sea level, suggesting that seawater intrusion may occur. A time-domain electromagnetic (TDEM) survey, based on 28 soundings, was conducted in Wadi Al Ayn and Daroufa plains to delineate the saline groundwater. Based on longitudinal and transversal resistivity two-dimensional pseudosections calibrated with boring data, the extent of saline water was identified. Geochemical tracers were combined with the resistivity dataset to differentiate the origin of groundwater salinization. In the upstream part of the plain, the infiltration of oilfield brine through the sandy bed of Wadi Al Ayn seems to have a considerable effect on groundwater salinization. However, in the coastal part of the aquifer, groundwater salinization is due to seawater intrusion and the saltwater is reaching an inland extent around 1.3 km from the shoreline. The contribution ratios of saline water bodies derived from the inverted chloride data vary for the oilfield brine from 1 to 13 % and for the seawater from 2 to 21 %.

Adaptive sampling of AEM transients

NASA Astrophysics Data System (ADS)

Di Massa, Domenico; Florio, Giovanni; Viezzoli, Andrea

2016-02-01

This paper focuses on the sampling of the electromagnetic transient as acquired by airborne time-domain electromagnetic (TDEM) systems. Typically, the sampling of the electromagnetic transient is done using a fixed number of gates whose width grows logarithmically (log-gating). The log-gating has two main benefits: improving the signal to noise (S/N) ratio at late times, when the electromagnetic signal has amplitudes equal or lower than the natural background noise, and ensuring a good resolution at the early times. However, as a result of fixed time gates, the conventional log-gating does not consider any geological variations in the surveyed area, nor the possibly varying characteristics of the measured signal. We show, using synthetic models, how a different, flexible sampling scheme can increase the resolution of resistivity models. We propose a new sampling method, which adapts the gating on the base of the slope variations in the electromagnetic (EM) transient. The use of such an alternative sampling scheme aims to get more accurate inverse models by extracting the geoelectrical information from the measured data in an optimal way.

Transient electromagnetic sounding for groundwater

USGS Publications Warehouse

Fitterman, David V.; Stewart, Mark T.

1986-01-01

The feasibility of using the transient electromagnetic sounding (TS or TDEM) method for groundwater exploration can be studied by means of numerical models. As examples of its applicability to groundwater exploration, we study four groundwater exploration problems: (1) mapping of alluvial fill and gravel zones over bedrock; (2) mapping of sand and gravel lenses in till; (3) detection of salt or brackish water interfaces in freshwater aquifers; and (4) determination of hydrostratigraphy. These groundwater problems require determination of the depth to bedrock; location of resistive, high‐porosity zones associated with fresh water; determination of formation resistivity to assess water quality; and determination of lithology and geometry, respectively. The TS method is best suited for locating conductive targets, and has very good vertical resolution. Unlike other sounding techniques where the receiver‐transmitter array must be expanded to sound more deeply, the depth of investigation for the TS method is a function of the length of time the transient is recorded. Present equipment limitations require that exploration targets with resistivities of 50 Ω ⋅ m or more be at least 50 m deep to determine their resistivity. The maximum depth of exploration is controlled by the geoelectrical section and background electromagnetic (EM) noise. For a particular exploration problem, numerical studies are recommended to determine if the target is detectable.

Interpretation of time-domain electromagnetic soundings in the Calico Hills area, Nevada Test Site, Nye County, Nevada

NASA Astrophysics Data System (ADS)

Kauahikaua, J.

A controlled source, time domain electromagnetic (TDEM) sounding survey was conducted in the Calico Hills area of the Nevada Test Site (NTS). The geoelectric structure was determined as an aid in the evaluation of the site for possible future storage of spent nuclear fuel or high level nuclear waste. The data were initially interpreted with a simple scheme that produces an apparent resistivity versus depth curve from the vertical magnetic field data. These curves are qualitatively interpreted much like standard Schlumberger resistivity sounding curves. Final interpretation made use of a layered earth Marquardt inversion computer program. The results combined with those from a set of Schlumberger soundings in the area show that there is a moderately resistive basement at a depth no greater than 800 meters. The basement resistivity is greater than 100 ohm meters.

TDEM AND NUMIS (PLUS) SOUNDINGS AT THE ASH MEADOWS NATIONAL WILDLIFE REFUGE: A CASE STUDY

EPA Science Inventory

During the summer of 2002, a cooperative project between the U.S. Geological Survey, the U.S. Environmental Protection Agency, and the Bureau de Recherches Geologiques et Minieres was undertaken to evaluate and gain knowledge of the Iris NUMIS instrument. The system was deployed ...

Impact of tillage on soil magnetic properties: results over thirty years different cultivation plots

NASA Astrophysics Data System (ADS)

Thiesson, Julien; Kessouri, Pauline; Buvat, Solène; Tabbagh, Alain

2010-05-01

Cultivation may favour or not different processes such as air and water circulation, organic matter and fertilizers supplies..., consequently it can a priori induce significant changes in local oxido-reduction conditions which determine the magnetic properties of soils: the soil magnetic signal. If laboratory measurements on soil samples can be slow and irreversible, it is also possible to perform in field measurements by using electromagnetic devices that allow quick and easy measuring over the relevant soil thicknesses both in time (TDEM) and frequency (FDEM) domains. The object of this study is to compare the variation of two magnetic properties (magnetic susceptibility, measured by FDEM apparatus and magnetic viscosity measured by TDEM apparatus) and there ratio along depth for three different types of tillage (no tillage, ploughing, and simplified tillage). An experimental plot of 80 m by 50 m total area, on which these three types of tillage have been conducted for more than thirty years, was surveyed. The plot is divided in five strips of 16 m by 50 m area, each of which being cultivated by one type of tillage only. Each strip is divided in two parts, one half with nitrogen-fixing crop during intercultivation winter period and the other half with bare soil during this period. On each part, the variation along depth of both magnetic properties was assessed by surveying with different devices corresponding to three different volumes of investigation. For the magnetic susceptibility measurements the devices used were the MS2 of Bartington Ltd with the MS2D probe and the CS60 a slingram prototype use in VCP and HCP configurations. For the magnetic viscosity, the devices used were the DECCO from Littlemore ltd. And the VC100, a slingram prototype, used at two heights. Eleven values of the two magnetic properties have been recorded using each device and their medians calculated. The data were inverted to define the median magnetic profiles of each half

Fabrication and Design Testing of 4 Petals for Deployable Starshade Prototype : JPL Summer Internship Program : Final Report

NASA Technical Reports Server (NTRS)

Paxton, Laurel

2012-01-01

One of the next steps in the exoplanet search is the development of occulter technology. Starlight suppression for a telescope would provide the ability to more accurately find and characterize potential true-Earth analogs. Coronagraphs have been the subject of much research in recent years but have yet to prove themselves a feasible approach. Attention has now turned to external occulters or starshades. A large occulting mask in front of a telescope should provide a comparable optical resolution to a coronagraph. Under a TDEM grant, a proposed starshade design was demonstrated to exceed coronagraph resolution by at least an order of magnitude. The current project is to demonstrate that the current design can be manufactured and then properly deployed. 4 sample starshade petals were constructed, ready to be attached to a pre-existing deployment truss. Time was spent detailing and modifying the petal construction process, so that future petals could be constructed at a more accurate and faster pace.

Shallow subsurface imaging of the Piano di Pezza active normal fault (central Italy) by high-resolution refraction and electrical resistivity tomography coupled with time-domain electromagnetic data

NASA Astrophysics Data System (ADS)

Villani, Fabio; Tulliani, Valerio; Sapia, Vincenzo; Fierro, Elisa; Civico, Riccardo; Pantosti, Daniela

2015-12-01

The Piano di Pezza fault is the central section of the 35 km long L'Aquila-Celano active normal fault-system in the central Apennines of Italy. Although palaeoseismic data document high Holocene vertical slip rates (˜1 mm yr-1) and a remarkable seismogenic potential of this fault, its subsurface setting and Pleistocene cumulative displacement are still poorly known. We investigated for the first time the shallow subsurface of a key section of the main Piano di Pezza fault splay by means of high-resolution seismic and electrical resistivity tomography coupled with time-domain electromagnetic soundings (TDEM). Our surveys cross a ˜5-m-high fault scarp that was generated by repeated surface-rupturing earthquakes displacing Holocene alluvial fans. We provide 2-D Vp and resistivity images, which show significant details of the fault structure and the geometry of the shallow basin infill material down to 50 m depth. Our data indicate that the upper fault termination has a sub-vertical attitude, in agreement with palaeoseismological trench evidence, whereas it dips ˜50° to the southwest in the deeper part. We recognize some low-velocity/low-resistivity regions in the fault hangingwall that we relate to packages of colluvial wedges derived from scarp degradation, which may represent the record of some Holocene palaeo-earthquakes. We estimate a ˜13-15 m throw of this fault splay since the end of the Last Glacial Maximum (˜18 ka), leading to a 0.7-0.8 mm yr-1 throw rate that is quite in accordance with previous palaeoseismic estimation of Holocene vertical slip rates. The 1-D resistivity models from TDEM soundings collected along the trace of the electrical profile significantly match with 2-D resistivity images. Moreover, they indicate that in the fault hangingwall, ˜200 m away from the surface fault trace, the pre-Quaternary carbonate basement is at ˜90-100 m depth. We therefore provide a minimal ˜150-160 m estimate of the cumulative throw of the Piano di Pezza

Dynamics and internal structure of an Alaskan debris-covered glacier from repeat airborne photogrammetry and surface geophysics

NASA Astrophysics Data System (ADS)

Holt, John; Levy, Joseph; Petersen, Eric; Larsen, Chris; Fahnestock, Mark

2016-04-01

Debris-covered glaciers and rock glaciers encompass a range of compositions and activity, and can be useful paleoclimate indicators. They also respond differently to ongoing climate change than glaciers without a protective cover. Their flow dynamics are not well understood, and their unique surface morphologies, including lobate fronts and arcuate ridges, likely result from viscous flow influenced by a combination of composition, structure, and climatic factors. However, basic connections between flow kinematics and surface morphology have not yet been established, limiting our ability to understand these features. In order to begin to address this problem we have undertaken airborne and surface studies of multiple debris-covered glaciers in Alaska and the western U.S. Sourdough Rock Glacier in the St. Elias Mountains, Alaska, is completely debris-covered and exhibits numerous transverse compressional ridges. Its trunk also exhibits highly regular bumps and swales with a wavelength of ~175 m and amplitudes up to 12 m. In the middle trunk, lineations (boulder trains and furrows) bend around a point roughly 200m from the eastern edge. We acquired five high-resolution airborne surveys of Sourdough Rock Glacier between late 2013 and late 2015 using lidar and photogrammetry to assess annual and seasonal change at the sub-meter level. Differencing the DTMs provides vertical change while feature tracking in orthophotos provide horizontal velocities that indicate meters of annual motion. The flow field is highly correlated with surface features; in particular, compressional ridges in the lower lobe. Stranded, formerly active lobes are also apparent. Surface geophysical studies were undertaken to constrain internal structure and composition using a combination of ground-penetrating radar (GPR) at 50 and 100 MHz in six transects, and time-domain electromagnetic (TDEM) measurements at 47 locations, primarily in an along-flow transect and two cross-flow transects. We infer

Recent progress on external occulter technology for imaging exosolar planets

NASA Astrophysics Data System (ADS)

Kasdin, N. J.; Vanderbei, R. J.; Sirbu, D.; Samuels, J.; Shaklan, S.; Lisman, D.; Thomson, M.; Cady, E.; Martin, S.

Imaging planets orbiting nearby stars requires a system for suppressing the host starlight by at least ten orders of magnitude. One such approach uses an external occulter, a satellite flying far from the telescope and employing a large screen, or starshade, to suppress the incoming starlight. This trades the added complexity of building the precisely shaped starshade and flying it in formation against simplifications in the telescope since extremely precise wavefront control is no longer necessary. Much progress has been made recently in designing, testing and manufacturing starshade technology. In this paper we describe the design of starshades and report on recent accomplishments in manufacturing and measuring a prototype occulter petal as part of NASA's first Technology Development for Exoplanet Missions (TDEM) program. We demonstrate that the as-built petal is consistent with a full-size occulter achieving better than 10-10 contrast. We also discuss laboratory testing at the Princeton Occulter Testbed. These experiments use sub-scale, long-distance beam propagation to verify the diffraction analysis associated with occulter starlight suppression. We demonstrate roughly 10-10 suppression in the laboratory and discuss the important challenges and limitations.

Seismic velocities to characterize the soil-aquifer continuum on the Orgeval experimental basin (France)

NASA Astrophysics Data System (ADS)

Pasquet, S.; Ludovic, B.; Dhemaied, A.; Flipo, N.; Guérin, R.; Mouhri, A.; Faycal, R.; Vitale, Q.

2013-12-01

Among geophysical methods applied to hydrogeology, seismic prospecting is frequently confined to the characterization of aquifers geometry. The combined study of pressure- (P) and shear- (SH) wave velocities (respectively Vp and Vs) can however provide information about the aquifer parameters, as it is commonly done for most fluids in hydrocarbon exploration. This approach has recently been proposed in sandy aquifers with the estimation of Vp/Vs ratio. In order to address such issues in more complex aquifer systems (e.g. unconsolidated, heterogeneous or low-permeability media) we carried out P- and SH-wave seismic surveys on the Orgeval experimental basin (70 km east from Paris, France). This basin drains a multi-layer aquifer system monitored by a network of piezometers. The upper part of the aquifer system is characterized by tabular layers well delineated all over the basin thanks to Electrical Resistivity Tomography (ERT), Time Domain ElectroMagnetic (TDEM) soundings and wells. But the lateral variability of the intrinsic properties in each layer raises questions regarding the hydrodynamics of the upper aquifer and the validity of interpolations between piezometers. A simple interpretation of P- and SH-wave first arrivals for tabular models provides 1D velocity structures in very good agreement with the stratification anticipated from ERT and nearby geological logs. Vp/Vs ratios show a strong contrast at a depth consistent with the observed water table level, reinforcing the assumption of a free upper aquifer in the area. Similar experiments have to be conducted under different hydrological conditions to validate these observations. Anticipating the need to propose lateral applications of the method, we additionally performed tomographic inversions of the recorded data to retrieve 2D Vp and Vs models. If interpreted independently, both models fail to depict the stratification of the medium and the water table level cannot be straightforwardly identified

Structure and evolution of an active resurgent dome evidenced by geophysical investigations: The Yenkahe dome-Yasur volcano system (Siwi caldera, Vanuatu)

NASA Astrophysics Data System (ADS)

Brothelande, E.; Lénat, J.-F.; Chaput, M.; Gailler, L.; Finizola, A.; Dumont, S.; Peltier, A.; Bachèlery, P.; Barde-Cabusson, S.; Byrdina, S.; Menny, P.; Colonge, J.; Douillet, G. A.; Letort, J.; Letourneur, L.; Merle, O.; Di Gangi, F.; Nakedau, D.; Garaebiti, E.

2016-08-01

In this contribution, we focus on one of the most active resurgences on Earth, that of the Yenkahe dome in the Siwi caldera (Tanna Island, Vanuatu), which is associated with the persistently active Yasur volcano. Gravity and magnetic surveys have been carried out over the past few years in the area, as well as electrical methods including electrical resistivity tomography (ERT), time domain electro-magnetics (TDEM) and self-potential (SP). These investigations were completed by thermometry, CO2 soil gas measurements, field observations and sampling. This multi-method approach allows geological structures within the caldera to be identified, as well as associated hydrothermal features. The global structure of the caldera is deduced from gravity data, which shows the caldera rim as a high density structure. Large lava fields, emplaced before and after the onset of resurgence, are evidenced by combined gravity, magnetic and resistivity signals. In the middle of the caldera, the Yenkahe dome apparently results from a combination of volcanic and tectonic events, showing that lava extrusion and resurgence have been operating simultaneously or alternately during the Siwi caldera post-collapse history. There is a clear distinction between the western and eastern parts of the dome. The western part is older and records the growth of an initial volcanic cone and the formation of a small caldera. This small caldera (paleo-Yasur caldera), partially filled with lava flows, is the present-day focus of volcanic activity and associated fluid circulation and alteration. The eastern part of the dome is presumably younger, and is characterized by intense, extensive hydrothermal alteration and activity. Its northern part is covered by lava flow piles and exhibits a shallow hydrothermal zone in ERT. The southern part has hydrothermal alteration and activity extending at least down to the base of the resurgent dome. This part of the dome is built up of low cohesion rock and is thus

Apacheta, a new geothermal prospect in Northern Chile

DOE Office of Scientific and Technical Information (OSTI.GOV)

Urzua, Luis; Powell, Tom; Cumming, William B.

2002-05-24

The discovery of two high-temperature fumaroles, with gas geochemistry compatible with an economic geothermal system, established Apacheta as one of the most attractive geothermal exploration prospects in northern Chile. These remote fumaroles at 5,150 m elevation were first sampled in 1999 by ENAP and its partners, following up on the reports of a CODELCO water exploration well that flowed small amounts of dry steam at 4,540 m elevation in the valley 4.5 km east of the fumaroles. The prospect is associated with a Plio-Pleistocene volcanic complex located within a NW-trending graben along the axis of the high Andes. The regionalmore » water table is 4,200 masl. There are no hot springs, just the 88 degrees C steam well and the 109 degrees and 118 degrees C fumaroles with gas compositions that indicate reservoir temperatures of greater than or equal to 250 degrees C, using a variety of gas geothermometers. An MT-TDEM survey was completed in 2001-2002 by Geotermica del Norte (SDN), an ENAP-C ODELCO partnership, to explore the Apacheta geothermal concession. The survey results indicated that base of the low resistivity clay cap has a structural apex just west of the fumaroles, a pattern typically associated with shallow permeability within a high temperature geothermal resource. SGN plans to drill at least one exploration well in 2002-03 to characterize a possible economic resource at Apacheta.« less

Heterogeneity of hydrodynamic properties and groundwater circulation of a coastal andesitic volcanic aquifer controlled by tectonic induced faults and rock fracturing - Martinique island (Lesser Antilles - FWI)

NASA Astrophysics Data System (ADS)

Vittecoq, B.; Reninger, P. A.; Violette, S.; Martelet, G.; Dewandel, B.; Audru, J. C.

2015-10-01

We conducted a multidisciplinary study to analyze the structure and the hydrogeological functioning of an andesitic coastal aquifer and to highlight the importance of faults and associated rock fracturing on groundwater flow. A helicopter-borne geophysical survey with an unprecedented resolution (SkyTEM) was flown over this aquifer in 2013. TDEM resistivity, total magnetic intensity, geological and hydrogeological data from 30 boreholes and two pumping tests were correlated, including one which lasted an exceptional 15 months. We demonstrate that heterogeneous hydrodynamic properties and channelized flows result from tectonically-controlled aquifer compartmentalization along the structural directions of successive tectonic phases. Significant fracturing of the central compartment results in enhanced hydrodynamic properties of the aquifer and an inverse relationship between electrical resistivity and transmissivity. Basalts within the fractured compartment have lower resistivity and higher permeability than basalts outside the compartment. Pumping tests demonstrate that the key factor is the hydraulic conductivity contrast between compartments rather than the hydrodynamic properties of the fault structure. In addition, compartmentalization and associated transmissivity contrasts protect the aquifer from seawater intrusion. Finally, unlike basaltic volcanic islands, the age of the volcanic formations is not the key factor that determines hydrodynamic properties of andesitic islands. Basalts that are several million years old (15 Ma here) have favorable hydrodynamic properties that are generated or maintained by earthquakes/faulting that result from active subduction beneath these islands, which is superimposed on their primary permeability.

Demonstrating Starshade Performance as Part of NASA's Technology Development for Exoplanet Missions

NASA Astrophysics Data System (ADS)

Kasdin, N. Jeremy; Spergel, D. N.; Vanderbei, R. J.; Lisman, D.; Shaklan, S.; Thomson, M. W.; Walkemeyer, P. E.; Bach, V. M.; Oakes, E.; Cady, E. J.; Martin, S. R.; Marchen, L. F.; Macintosh, B.; Rudd, R.; Mikula, J. A.; Lynch, D. H.

2012-01-01

In this poster we describe the results of our project to design, manufacture, and measure a prototype starshade petal as part of the Technology Development for Exoplanet Missions program. An external occult is a satellite employing a large screen, or starshade,that flies in formation with a spaceborne telescope to provide the starlight suppression needed for detecting and characterizing exoplanets. Among the advantages of using an occulter are the broadband allowed for characterization and the removal of light for the observatory, greatly relaxing the requirements on the telescope and instrument. In this first two-year phase we focused on the key requirement of manufacturing a precision petal with the precise tolerances needed to meet the overall error budget. These tolerances are established by modeling the effect that various mechanical and thermal errors have on scatter in the telescope image plane and by suballocating the allowable contrast degradation between these error sources. We show the results of this analysis and a representative error budget. We also present the final manufactured occulter petal and the metrology on its shape that demonstrates it meets requirements. We show that a space occulter built of petals with the same measured shape would achieve better than 1e-9 contrast. We also show our progress in building and testing sample edges with the sharp radius of curvature needed for limiting solar glint. Finally, we describe our plans for the second TDEM phase.

Flood Inundation Mapping and Emergency Operations during Hurricane Harvey

NASA Astrophysics Data System (ADS)

Fang, N. Z.; Cotter, J.; Gao, S.; Bedient, P. B.; Yung, A.; Penland, C.

2017-12-01

Hurricane Harvey struck the Gulf Coast as Category 4 on August 25, 2017 with devastating and life-threatening floods in Texas. Harris County received up to 49 inches of rainfall over a 5-day period and experienced flooding level and impacts beyond any previous storm in Houston's history. The depth-duration-frequency analysis reveals that the areal average rainfall for Brays Bayou surpasses the 500-year rainfall in both 24 and 48 hours. To cope with this unprecedented event, the researchers at the University of Texas at Arlington and Rice University worked closely with the U.S. Army Corps of Engineers (USACE), the National Weather Service (NWS), the Texas Division of Emergency Management (TDEM), Walter P. Moore and Associates, Inc. and Halff Associates, to conduct a series of meteorological, hydrologic and hydraulic analyses to delineate flood inundation maps. Up to eight major watersheds in Harris County were delineated based the available QPE data from WGRFC. The inundation map over Brays Bayou with their impacts from Hurricane Harvey was delineated in comparison with those of 100-, 500-year, and Probable Maximum Precipitation (PMP) design storms. This presentation will provide insights for both engineers and planners to re-evaluate the existing flood infrastructure and policy, which will help build Houston stronger for future extreme storms. The collaborative effort among the federal, academic, and private entities clearly demonstrates an effective approach for flood inundation mapping initiatives for the nation.

Generalization of the Engineering Method to the UNIVERSAL METHOD.

ERIC Educational Resources Information Center

Koen, Billy Vaughn

1987-01-01

Proposes that there is a universal method for all realms of knowledge. Reviews Descartes's definition of the universal method, the engineering definition, and the philosophical basis for the universal method. Contends that the engineering method best represents the universal method. (ML)

Methods Beyond Methods: A Model for Africana Graduate Methods Training.

PubMed

Best, Latrica E; Byrd, W Carson

2014-06-01

A holistic graduate education can impart not just tools and knowledge, but critical positioning to fulfill many of the original missions of Africana Studies programs set forth in the 1960s and 1970s. As an interdisciplinary field with many approaches to examining the African Diaspora, the methodological training of graduate students can vary across graduate programs. Although taking qualitative methods courses are often required of graduate students in Africana Studies programs, and these programs offer such courses, rarely if ever are graduate students in these programs required to take quantitative methods courses, let alone have these courses offered in-house. These courses can offer Africana Studies graduate students new tools for their own research, but more importantly, improve their knowledge of quantitative research of diasporic communities. These tools and knowledge can assist with identifying flawed arguments about African-descended communities and their members. This article explores the importance of requiring and offering critical quantitative methods courses in graduate programs in Africana Studies, and discusses the methods requirements of one graduate program in the field as an example of more rigorous training that other programs could offer graduate students.

Methods Beyond Methods: A Model for Africana Graduate Methods Training

PubMed Central

Best, Latrica E.; Byrd, W. Carson

2018-01-01

A holistic graduate education can impart not just tools and knowledge, but critical positioning to fulfill many of the original missions of Africana Studies programs set forth in the 1960s and 1970s. As an interdisciplinary field with many approaches to examining the African Diaspora, the methodological training of graduate students can vary across graduate programs. Although taking qualitative methods courses are often required of graduate students in Africana Studies programs, and these programs offer such courses, rarely if ever are graduate students in these programs required to take quantitative methods courses, let alone have these courses offered in-house. These courses can offer Africana Studies graduate students new tools for their own research, but more importantly, improve their knowledge of quantitative research of diasporic communities. These tools and knowledge can assist with identifying flawed arguments about African-descended communities and their members. This article explores the importance of requiring and offering critical quantitative methods courses in graduate programs in Africana Studies, and discusses the methods requirements of one graduate program in the field as an example of more rigorous training that other programs could offer graduate students. PMID:29710883

Newton's method

DOE Office of Scientific and Technical Information (OSTI.GOV)

More, J. J.; Sorensen, D. C.

1982-02-01

Newton's method plays a central role in the development of numerical techniques for optimization. In fact, most of the current practical methods for optimization can be viewed as variations on Newton's method. It is therefore important to understand Newton's method as an algorithm in its own right and as a key introduction to the most recent ideas in this area. One of the aims of this expository paper is to present and analyze two main approaches to Newton's method for unconstrained minimization: the line search approach and the trust region approach. The other aim is to present some of themore » recent developments in the optimization field which are related to Newton's method. In particular, we explore several variations on Newton's method which are appropriate for large scale problems, and we also show how quasi-Newton methods can be derived quite naturally from Newton's method.« less

Study of New Method Combined Ultra-High Frequency (UHF) Method and Ultrasonic Method on PD Detection for GIS

NASA Astrophysics Data System (ADS)

Li, Yanran; Chen, Duo; Zhang, Jiwei; Chen, Ning; Li, Xiaoqi; Gong, Xiaojing

2017-09-01

GIS (gas insulated switchgear), is an important equipment in power system. Partial discharge plays an important role in detecting the insulation performance of GIS. UHF method and ultrasonic method frequently used in partial discharge (PD) detection for GIS. It is necessary to investigate UHF method and ultrasonic method for partial discharge in GIS. However, very few studies have been conducted on the method combined this two methods. From the view point of safety, a new method based on UHF method and ultrasonic method of PD detection for GIS is proposed in order to greatly enhance the ability of anti-interference of signal detection and the accuracy of fault localization. This paper presents study aimed at clarifying the effect of the new method combined UHF method and ultrasonic method. Partial discharge tests were performed in laboratory simulated environment. Obtained results show the ability of anti-interference of signal detection and the accuracy of fault localization for this new method combined UHF method and ultrasonic method.

A Novel Polygonal Finite Element Method: Virtual Node Method

NASA Astrophysics Data System (ADS)

Tang, X. H.; Zheng, C.; Zhang, J. H.

2010-05-01

Polygonal finite element method (PFEM), which can construct shape functions on polygonal elements, provides greater flexibility in mesh generation. However, the non-polynomial form of traditional PFEM, such as Wachspress method and Mean Value method, leads to inexact numerical integration. Since the integration technique for non-polynomial functions is immature. To overcome this shortcoming, a great number of integration points have to be used to obtain sufficiently exact results, which increases computational cost. In this paper, a novel polygonal finite element method is proposed and called as virtual node method (VNM). The features of present method can be list as: (1) It is a PFEM with polynomial form. Thereby, Hammer integral and Gauss integral can be naturally used to obtain exact numerical integration; (2) Shape functions of VNM satisfy all the requirements of finite element method. To test the performance of VNM, intensive numerical tests are carried out. It found that, in standard patch test, VNM can achieve significantly better results than Wachspress method and Mean Value method. Moreover, it is observed that VNM can achieve better results than triangular 3-node elements in the accuracy test.

Evaluation of Two New Smoothing Methods in Equating: The Cubic B-Spline Presmoothing Method and the Direct Presmoothing Method

ERIC Educational Resources Information Center

Cui, Zhongmin; Kolen, Michael J.

2009-01-01

This article considers two new smoothing methods in equipercentile equating, the cubic B-spline presmoothing method and the direct presmoothing method. Using a simulation study, these two methods are compared with established methods, the beta-4 method, the polynomial loglinear method, and the cubic spline postsmoothing method, under three sample…

Mining method selection by integrated AHP and PROMETHEE method.

PubMed

Bogdanovic, Dejan; Nikolic, Djordje; Ilic, Ivana

2012-03-01

Selecting the best mining method among many alternatives is a multicriteria decision making problem. The aim of this paper is to demonstrate the implementation of an integrated approach that employs AHP and PROMETHEE together for selecting the most suitable mining method for the "Coka Marin" underground mine in Serbia. The related problem includes five possible mining methods and eleven criteria to evaluate them. Criteria are accurately chosen in order to cover the most important parameters that impact on the mining method selection, such as geological and geotechnical properties, economic parameters and geographical factors. The AHP is used to analyze the structure of the mining method selection problem and to determine weights of the criteria, and PROMETHEE method is used to obtain the final ranking and to make a sensitivity analysis by changing the weights. The results have shown that the proposed integrated method can be successfully used in solving mining engineering problems.

Birth Control Methods

MedlinePlus

... Z Health Topics Birth control methods Birth control methods > A-Z Health Topics Birth control methods fact ... To receive Publications email updates Submit Birth control methods Birth control (contraception) is any method, medicine, or ...

Regeneration methods

Treesearch

James P. Barnett; James B. Baker

1991-01-01

Southern pines can be regenerated naturally, by clearcutting, seedtree, shelterwood, or selection reproduction culling methods, or artificially, by direct seeding or by planting either container or bareroot seedlings. All regeneration methods have inherent advantages: and disadvantages; thus, land managers must consider many factors before deciding on a specific method...

Safety training for working youth: Methods used versus methods wanted.

PubMed

Zierold, Kristina M

2016-04-07

Safety training is promoted as a tool to prevent workplace injury; however, little is known about the safety training experiences young workers get on-the-job. Furthermore, nothing is known about what methods they think would be the most helpful for learning about safe work practices. To compare safety training methods teens get on the job to those safety training methods teens think would be the best for learning workplace safety, focusing on age differences. A cross-sectional survey was administered to students in two large high schools in spring 2011. Seventy percent of working youth received safety training. The top training methods that youth reported getting at work were safety videos (42%), safety lectures (25%), and safety posters/signs (22%). In comparison to the safety training methods used, the top methods youth wanted included videos (54%), hands-on (47%), and on-the-job demonstrations (34%). This study demonstrated that there were differences in training methods that youth wanted by age; with older youth seemingly wanting more independent methods of training and younger teens wanting more involvement. Results indicate that youth want methods of safety training that are different from what they are getting on the job. The differences in methods wanted by age may aid in developing training programs appropriate for the developmental level of working youth.

A comparison of Ki-67 counting methods in luminal Breast Cancer: The Average Method vs. the Hot Spot Method.

PubMed

Jang, Min Hye; Kim, Hyun Jung; Chung, Yul Ri; Lee, Yangkyu; Park, So Yeon

2017-01-01

In spite of the usefulness of the Ki-67 labeling index (LI) as a prognostic and predictive marker in breast cancer, its clinical application remains limited due to variability in its measurement and the absence of a standard method of interpretation. This study was designed to compare the two methods of assessing Ki-67 LI: the average method vs. the hot spot method and thus to determine which method is more appropriate in predicting prognosis of luminal/HER2-negative breast cancers. Ki-67 LIs were calculated by direct counting of three representative areas of 493 luminal/HER2-negative breast cancers using the two methods. We calculated the differences in the Ki-67 LIs (ΔKi-67) between the two methods and the ratio of the Ki-67 LIs (H/A ratio) of the two methods. In addition, we compared the performance of the Ki-67 LIs obtained by the two methods as prognostic markers. ΔKi-67 ranged from 0.01% to 33.3% and the H/A ratio ranged from 1.0 to 2.6. Based on the receiver operating characteristic curve method, the predictive powers of the KI-67 LI measured by the two methods were similar (Area under curve: hot spot method, 0.711; average method, 0.700). In multivariate analysis, high Ki-67 LI based on either method was an independent poor prognostic factor, along with high T stage and node metastasis. However, in repeated counts, the hot spot method did not consistently classify tumors into high vs. low Ki-67 LI groups. In conclusion, both the average and hot spot method of evaluating Ki-67 LI have good predictive performances for tumor recurrence in luminal/HER2-negative breast cancers. However, we recommend using the average method for the present because of its greater reproducibility.

A comparison of Ki-67 counting methods in luminal Breast Cancer: The Average Method vs. the Hot Spot Method

PubMed Central

Jang, Min Hye; Kim, Hyun Jung; Chung, Yul Ri; Lee, Yangkyu

2017-01-01

In spite of the usefulness of the Ki-67 labeling index (LI) as a prognostic and predictive marker in breast cancer, its clinical application remains limited due to variability in its measurement and the absence of a standard method of interpretation. This study was designed to compare the two methods of assessing Ki-67 LI: the average method vs. the hot spot method and thus to determine which method is more appropriate in predicting prognosis of luminal/HER2-negative breast cancers. Ki-67 LIs were calculated by direct counting of three representative areas of 493 luminal/HER2-negative breast cancers using the two methods. We calculated the differences in the Ki-67 LIs (ΔKi-67) between the two methods and the ratio of the Ki-67 LIs (H/A ratio) of the two methods. In addition, we compared the performance of the Ki-67 LIs obtained by the two methods as prognostic markers. ΔKi-67 ranged from 0.01% to 33.3% and the H/A ratio ranged from 1.0 to 2.6. Based on the receiver operating characteristic curve method, the predictive powers of the KI-67 LI measured by the two methods were similar (Area under curve: hot spot method, 0.711; average method, 0.700). In multivariate analysis, high Ki-67 LI based on either method was an independent poor prognostic factor, along with high T stage and node metastasis. However, in repeated counts, the hot spot method did not consistently classify tumors into high vs. low Ki-67 LI groups. In conclusion, both the average and hot spot method of evaluating Ki-67 LI have good predictive performances for tumor recurrence in luminal/HER2-negative breast cancers. However, we recommend using the average method for the present because of its greater reproducibility. PMID:28187177

Integrated force method versus displacement method for finite element analysis

NASA Technical Reports Server (NTRS)

Patnaik, S. N.; Berke, L.; Gallagher, R. H.

1991-01-01

A novel formulation termed the integrated force method (IFM) has been developed in recent years for analyzing structures. In this method all the internal forces are taken as independent variables, and the system equilibrium equations (EEs) are integrated with the global compatibility conditions (CCs) to form the governing set of equations. In IFM the CCs are obtained from the strain formulation of St. Venant, and no choices of redundant load systems have to be made, in constrast to the standard force method (SFM). This property of IFM allows the generation of the governing equation to be automated straightforwardly, as it is in the popular stiffness method (SM). In this report IFM and SM are compared relative to the structure of their respective equations, their conditioning, required solution methods, overall computational requirements, and convergence properties as these factors influence the accuracy of the results. Overall, this new version of the force method produces more accurate results than the stiffness method for comparable computational cost.

Integrated force method versus displacement method for finite element analysis

NASA Technical Reports Server (NTRS)

Patnaik, Surya N.; Berke, Laszlo; Gallagher, Richard H.

1990-01-01

A novel formulation termed the integrated force method (IFM) has been developed in recent years for analyzing structures. In this method all the internal forces are taken as independent variables, and the system equilibrium equations (EE's) are integrated with the global compatibility conditions (CC's) to form the governing set of equations. In IFM the CC's are obtained from the strain formulation of St. Venant, and no choices of redundant load systems have to be made, in constrast to the standard force method (SFM). This property of IFM allows the generation of the governing equation to be automated straightforwardly, as it is in the popular stiffness method (SM). In this report IFM and SM are compared relative to the structure of their respective equations, their conditioning, required solution methods, overall computational requirements, and convergence properties as these factors influence the accuracy of the results. Overall, this new version of the force method produces more accurate results than the stiffness method for comparable computational cost.

A Hybrid Lyot Coronagraph for the Direct Imaging and Spectroscopy of Exoplanet Systems: Recent Results and Prospects

NASA Technical Reports Server (NTRS)

Trauger, John; Moody, Dwight; Gordon, Brian; Krist, John; Mawet, Dimitri

2011-01-01

We report our best laboratory contrast demonstrations achieved to date. We review the design, fabrication, performance, and future prospects of a hybrid focal plane occulter for exoplanet coronagraphy. Composed of thickness-profiled metallic and dielectric thin films vacuum deposited on a fused silica substrate, the hybrid occulter uses two superimposed thin films for control over both the real and imaginary parts of the complex attenuation pattern. Together with a deformable mirror for adjustment of wavefront phase, the hybrid Lyot coronagraph potentially exceeds billion-to one contrast over dark fields extending to within angular separations of 3 lambda/D (3 x the cosmological constant / diameter of the telescope) from the central star, over spectral bandwidths of 20 percent or more, and with throughput efficiencies up to 60 percent. We report laboratory contrasts of 3 x 10 (sup -10) degrees over 2 percent bandwidths, 6 x 10 (sup -10) degrees over 10 percent bandwidths, and 2 x 10 (sup -9) over 20 percent bandwidths, achieved across high contrast fields extending from an inner working angle of 3 lambda/D to a radius of 15 lambda/D. Occulter performance is analyzed in light of recent experiments and optical models, and prospects for further improvements are summarized. The science capabilities of the hybrid Lyot coronagraph are compared with requirements of the ACCESS mission, a representative exoplanet space telescope concept study for the direct imaging and spectroscopy of exoplanet systems. This work has been supported by NASA's Technology Demonstration for Exoplanet Missions (TDEM) program.

Shallow End Response from ATEM

NASA Astrophysics Data System (ADS)

Vetrov, A.

2014-12-01

Different geological, hydrological, environmental and engineering targets are located shallow underground. The information collected with ATEM systems might be very useful for their study; although there are many deeper targets that the ATEM systems are traditionally used for. The idea to raise magnetic moment output and get deeper penetration response was one of the goals of ATEM systems development during the last decade. The shallow geology response was a trade for such systems, which sometimes were almost blind in the first hundred meter under surface. The possibility to achieve shallow end response from ATEM systems has become significant subject in last years. Several airborne TDEM systems got second higher frequency and lower magnetic moment signal to pick up shallow response together with deep one. Having a potential advantage such implementation raises complication and cost of the system. There's no need to receive 500 meter deep response when exploring shallow geology. P-THEM system having a compact size transmitter and relatively light weight is working on one base frequency at a time, but this frequency can be preset before a flight considering survey goals. A study of shallow geology response of the P-THEM system working on different base frequency has been conducted in 2014 in Ontario. The Alliston test area located in Southern Ontario has been flown with the P-THEM system working on base frequencies 30Hz and 90Hz. Results of the observations will be discussed in the presentation. The shallow end data can be used for mineral exploration applications and also for hydrological and environmental studies.

Problems d'elaboration d'une methode locale: la methode "Paris-Khartoum" (Problems in Implementing a Local Method: the Paris-Khartoum Method)

ERIC Educational Resources Information Center

Penhoat, Loick; Sakow, Kostia

1978-01-01

A description of the development and implementation of a method introduced in the Sudan that attempts to relate to Sudanese culture and to motivate students. The relationship between language teaching methods and the total educational system is discussed. (AMH)

A simple method for processing data with least square method

NASA Astrophysics Data System (ADS)

Wang, Chunyan; Qi, Liqun; Chen, Yongxiang; Pang, Guangning

2017-08-01

The least square method is widely used in data processing and error estimation. The mathematical method has become an essential technique for parameter estimation, data processing, regression analysis and experimental data fitting, and has become a criterion tool for statistical inference. In measurement data analysis, the distribution of complex rules is usually based on the least square principle, i.e., the use of matrix to solve the final estimate and to improve its accuracy. In this paper, a new method is presented for the solution of the method which is based on algebraic computation and is relatively straightforward and easy to understand. The practicability of this method is described by a concrete example.

Designing ROW Methods

NASA Technical Reports Server (NTRS)

Freed, Alan D.

1996-01-01

There are many aspects to consider when designing a Rosenbrock-Wanner-Wolfbrandt (ROW) method for the numerical integration of ordinary differential equations (ODE's) solving initial value problems (IVP's). The process can be simplified by constructing ROW methods around good Runge-Kutta (RK) methods. The formulation of a new, simple, embedded, third-order, ROW method demonstrates this design approach.

Compositions, antibodies, asthma diagnosis methods, and methods for preparing antibodies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jin, Hongjun; Zangar, Richard C.

Methods for preparing an antibody are provided with the method including incorporating 3-bromo-4-hydroxy-benzoic acid into a protein to form an antigen, immunizing a mammalian host with the antigen, and recovering an antibody having an affinity for the antigen from the host. Antibodies having a binding affinity for a monohalotyrosine are provided as well as composition comprising an antibody bound with monohalotyrosine. Compositions comprising a protein having a 3-bromo-4-hydroxy-benzoic acid moiety are also provided. Methods for evaluating the severity of asthma are provide with the methods including analyzing sputum of a patient using an antibody having a binding affinity for monohalotyrosine,more » and measuring the amount of antibody bound to protein. Methods for determining eosinophil activity in bodily fluid are also provided with the methods including exposing bodily fluid to an antibody having a binding affinity for monohalotyrosine, and measuring the amount of bound antibody to determine the eosinophil activity.« less

On Everhart Method

NASA Astrophysics Data System (ADS)

Pârv, Bazil

This paper deals with the Everhart numerical integration method, a well-known method in astronomical research. This method, a single-step one, is widely used for numerical integration of motion equation of celestial bodies. For an integration step, this method uses unequally-spaced substeps, defined by the roots of the so-called generating polynomial of Everhart's method. For this polynomial, this paper proposes and proves new recurrence formulae. The Maple computer algebra system was used to find and prove these formulae. Again, Maple seems to be well suited and easy to use in mathematical research.

The Value of Mixed Methods Research: A Mixed Methods Study

ERIC Educational Resources Information Center

McKim, Courtney A.

2017-01-01

The purpose of this explanatory mixed methods study was to examine the perceived value of mixed methods research for graduate students. The quantitative phase was an experiment examining the effect of a passage's methodology on students' perceived value. Results indicated students scored the mixed methods passage as more valuable than those who…

Mapping Mixed Methods Research: Methods, Measures, and Meaning

ERIC Educational Resources Information Center

Wheeldon, J.

2010-01-01

This article explores how concept maps and mind maps can be used as data collection tools in mixed methods research to combine the clarity of quantitative counts with the nuance of qualitative reflections. Based on more traditional mixed methods approaches, this article details how the use of pre/post concept maps can be used to design qualitative…

The preconditioned Gauss-Seidel method faster than the SOR method

NASA Astrophysics Data System (ADS)

Niki, Hiroshi; Kohno, Toshiyuki; Morimoto, Munenori

2008-09-01

In recent years, a number of preconditioners have been applied to linear systems [A.D. Gunawardena, S.K. Jain, L. Snyder, Modified iterative methods for consistent linear systems, Linear Algebra Appl. 154-156 (1991) 123-143; T. Kohno, H. Kotakemori, H. Niki, M. Usui, Improving modified Gauss-Seidel method for Z-matrices, Linear Algebra Appl. 267 (1997) 113-123; H. Kotakemori, K. Harada, M. Morimoto, H. Niki, A comparison theorem for the iterative method with the preconditioner (I+Smax), J. Comput. Appl. Math. 145 (2002) 373-378; H. Kotakemori, H. Niki, N. Okamoto, Accelerated iteration method for Z-matrices, J. Comput. Appl. Math. 75 (1996) 87-97; M. Usui, H. Niki, T.Kohno, Adaptive Gauss-Seidel method for linear systems, Internat. J. Comput. Math. 51(1994)119-125 [10

A new method for calculating ecological flow: Distribution flow method

NASA Astrophysics Data System (ADS)

Tan, Guangming; Yi, Ran; Chang, Jianbo; Shu, Caiwen; Yin, Zhi; Han, Shasha; Feng, Zhiyong; Lyu, Yiwei

2018-04-01

A distribution flow method (DFM) and its ecological flow index and evaluation grade standard are proposed to study the ecological flow of rivers based on broadening kernel density estimation. The proposed DFM and its ecological flow index and evaluation grade standard are applied into the calculation of ecological flow in the middle reaches of the Yangtze River and compared with traditional calculation method of hydrological ecological flow, method of flow evaluation, and calculation result of fish ecological flow. Results show that the DFM considers the intra- and inter-annual variations in natural runoff, thereby reducing the influence of extreme flow and uneven flow distributions during the year. This method also satisfies the actual runoff demand of river ecosystems, demonstrates superiority over the traditional hydrological methods, and shows a high space-time applicability and application value.

A Tale of Two Methods: Chart and Interview Methods for Identifying Delirium

PubMed Central

Saczynski, Jane S.; Kosar, Cyrus M.; Xu, Guoquan; Puelle, Margaret R.; Schmitt, Eva; Jones, Richard N.; Marcantonio, Edward R.; Wong, Bonnie; Isaza, Ilean; Inouye, Sharon K.

2014-01-01

Background Interview and chart-based methods for identifying delirium have been validated. However, relative strengths and limitations of each method have not been described, nor has a combined approach (using both interviews and chart), been systematically examined. Objectives To compare chart and interview-based methods for identification of delirium. Design, Setting and Participants Participants were 300 patients aged 70+ undergoing major elective surgery (majority were orthopedic surgery) interviewed daily during hospitalization for delirium using the Confusion Assessment Method (CAM; interview-based method) and whose medical charts were reviewed for delirium using a validated chart-review method (chart-based method). We examined rate of agreement on the two methods and patient characteristics of those identified using each approach. Predictive validity for clinical outcomes (length of stay, postoperative complications, discharge disposition) was compared. In the absence of a gold-standard, predictive value could not be calculated. Results The cumulative incidence of delirium was 23% (n= 68) by the interview-based method, 12% (n=35) by the chart-based method and 27% (n=82) by the combined approach. Overall agreement was 80%; kappa was 0.30. The methods differed in detection of psychomotor features and time of onset. The chart-based method missed delirium in CAM-identified patients laacking features of psychomotor agitation or inappropriate behavior. The CAM-based method missed chart-identified cases occurring during the night shift. The combined method had high predictive validity for all clinical outcomes. Conclusions Interview and chart-based methods have specific strengths for identification of delirium. A combined approach captures the largest number and the broadest range of delirium cases. PMID:24512042

The Chebyshev-Legendre method: Implementing Legendre methods on Chebyshev points

NASA Technical Reports Server (NTRS)

Don, Wai Sun; Gottlieb, David

1993-01-01

We present a new collocation method for the numerical solution of partial differential equations. This method uses the Chebyshev collocation points, but because of the way the boundary conditions are implemented, it has all the advantages of the Legendre methods. In particular, L2 estimates can be obtained easily for hyperbolic and parabolic problems.

Ensemble Methods

NASA Astrophysics Data System (ADS)

Re, Matteo; Valentini, Giorgio

2012-03-01

Ensemble methods are statistical and computational learning procedures reminiscent of the human social learning behavior of seeking several opinions before making any crucial decision. The idea of combining the opinions of different "experts" to obtain an overall “ensemble” decision is rooted in our culture at least from the classical age of ancient Greece, and it has been formalized during the Enlightenment with the Condorcet Jury Theorem[45]), which proved that the judgment of a committee is superior to those of individuals, provided the individuals have reasonable competence. Ensembles are sets of learning machines that combine in some way their decisions, or their learning algorithms, or different views of data, or other specific characteristics to obtain more reliable and more accurate predictions in supervised and unsupervised learning problems [48,116]. A simple example is represented by the majority vote ensemble, by which the decisions of different learning machines are combined, and the class that receives the majority of “votes” (i.e., the class predicted by the majority of the learning machines) is the class predicted by the overall ensemble [158]. In the literature, a plethora of terms other than ensembles has been used, such as fusion, combination, aggregation, and committee, to indicate sets of learning machines that work together to solve a machine learning problem [19,40,56,66,99,108,123], but in this chapter we maintain the term ensemble in its widest meaning, in order to include the whole range of combination methods. Nowadays, ensemble methods represent one of the main current research lines in machine learning [48,116], and the interest of the research community on ensemble methods is witnessed by conferences and workshops specifically devoted to ensembles, first of all the multiple classifier systems (MCS) conference organized by Roli, Kittler, Windeatt, and other researchers of this area [14,62,85,149,173]. Several theories have been

Unification of the complex Langevin method and the Lefschetzthimble method

NASA Astrophysics Data System (ADS)

Nishimura, Jun; Shimasaki, Shinji

2018-03-01

Recently there has been remarkable progress in solving the sign problem, which occurs in investigating statistical systems with a complex weight. The two promising methods, the complex Langevin method and the Lefschetz thimble method, share the idea of complexifying the dynamical variables, but their relationship has not been clear. Here we propose a unified formulation, in which the sign problem is taken care of by both the Langevin dynamics and the holomorphic gradient flow. We apply our formulation to a simple model in three different ways and show that one of them interpolates the two methods by changing the flow time.

Instructional Methods Tool

DTIC Science & Technology

2017-09-01

Research Product 2018-01 Instructional Methods Tool Jennifer S. Tucker U.S. Army Research Institute David R. James...Unclassified ii Research Product 2018-01 Instructional Methods Tool Jennifer S. Tucker U.S. Army Research Institute David R. James...1 RESEARCH OBJECTIVE ..............................................................................................................1 METHOD

Color image definition evaluation method based on deep learning method

NASA Astrophysics Data System (ADS)

Liu, Di; Li, YingChun

2018-01-01

In order to evaluate different blurring levels of color image and improve the method of image definition evaluation, this paper proposed a method based on the depth learning framework and BP neural network classification model, and presents a non-reference color image clarity evaluation method. Firstly, using VGG16 net as the feature extractor to extract 4,096 dimensions features of the images, then the extracted features and labeled images are employed in BP neural network to train. And finally achieve the color image definition evaluation. The method in this paper are experimented by using images from the CSIQ database. The images are blurred at different levels. There are 4,000 images after the processing. Dividing the 4,000 images into three categories, each category represents a blur level. 300 out of 400 high-dimensional features are trained in VGG16 net and BP neural network, and the rest of 100 samples are tested. The experimental results show that the method can take full advantage of the learning and characterization capability of deep learning. Referring to the current shortcomings of the major existing image clarity evaluation methods, which manually design and extract features. The method in this paper can extract the images features automatically, and has got excellent image quality classification accuracy for the test data set. The accuracy rate is 96%. Moreover, the predicted quality levels of original color images are similar to the perception of the human visual system.

Which method should be the reference method to evaluate the severity of rheumatic mitral stenosis? Gorlin's method versus 3D-echo.

PubMed

Pérez de Isla, Leopoldo; Casanova, Carlos; Almería, Carlos; Rodrigo, José Luis; Cordeiro, Pedro; Mataix, Luis; Aubele, Ada Lia; Lang, Roberto; Zamorano, José Luis

2007-12-01

Several studies have shown a wide variability among different methods to determine the valve area in patients with rheumatic mitral stenosis. Our aim was to evaluate if 3D-echo planimetry is more accurate than the Gorlin method to measure the valve area. Twenty-six patients with mitral stenosis underwent 2D and 3D-echo echocardiographic examinations and catheterization. Valve area was estimated by different methods. A median value of the mitral valve area, obtained from the measurements of three classical non-invasive methods (2D planimetry, pressure half-time and PISA method), was used as the reference method and it was compared with 3D-echo planimetry and Gorlin's method. Our results showed that the accuracy of 3D-echo planimetry is superior to the accuracy of the Gorlin method for the assessment of mitral valve area. We should keep in mind the fact that 3D-echo planimetry may be a better reference method than the Gorlin method to assess the severity of rheumatic mitral stenosis.

The Effects of Wideband Complex Electromagnetic Properties of Soils on Geophysical Sensor Performance

NASA Astrophysics Data System (ADS)

North, Ryan Elliot

Common near-surface geophysical methods such as time domain electromagnetic induction (TDEM) metal detectors and ground penetrating radar (GPR) suffer performance degradation as a function of site specific complex electromagnetic soil properties (permittivity, permeability and conductivity). Knowledge of these soil properties from the kHz to the GHz frequency range can be used to predict and improve sensor performance. A prototype permittivity probe was used to measure the complex permittivity and conductivity of the soil and calculate the GPR velocity and attenuation of the from the in-situ measurements. The prototype probe was capable of accurately predicting the GPR velocities when compared with the GPR measurement and could easily predict the attenuation which is difficult to determine from actual GPR data. Unfortunately the prototype probe here has one primarily deficiency which is the assumption that the soils where it is used are non-magnetic. To illustrate the problems with using this probe in magnetic soils I made soil analogues from commercially available magnetite and crushed silica powder then measured them using a common open ended coaxial probe followed by measurements with coaxial air- line fixture which can also calculate magnetic properties. The calculated permittivities are up to twice as high when measured with the coaxial probe as they are when measured with a coaxial airline fixture which will lead to incorrect estimates of GPR velocity and attenuation. To address the performance issues of metal detectors in magnetically viscous soils I created a magnetically viscous soil analogue that could be used in mine detection training lanes instead of importing soil from sites exhibiting magnetic viscosity. Five commercially available iron oxide nano-powders were tested as additives to create the soil analogues by measuring the magnetic viscosity of these iron oxides with a new prototype instrument and compared them to samples of magnetically viscous

76 FR 21673 - Alternative Efficiency Determination Methods and Alternate Rating Methods

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-18

... EERE-2011-BP-TP-00024] RIN 1904-AC46 Alternative Efficiency Determination Methods and Alternate Rating Methods AGENCY: Office of Energy Efficiency and Renewable Energy, Department of Energy. ACTION: Notice of... and data related to the use of computer simulations, mathematical methods, and other alternative...

Development of modelling method selection tool for health services management: from problem structuring methods to modelling and simulation methods.

PubMed

Jun, Gyuchan T; Morris, Zoe; Eldabi, Tillal; Harper, Paul; Naseer, Aisha; Patel, Brijesh; Clarkson, John P

2011-05-19

There is an increasing recognition that modelling and simulation can assist in the process of designing health care policies, strategies and operations. However, the current use is limited and answers to questions such as what methods to use and when remain somewhat underdeveloped. The aim of this study is to provide a mechanism for decision makers in health services planning and management to compare a broad range of modelling and simulation methods so that they can better select and use them or better commission relevant modelling and simulation work. This paper proposes a modelling and simulation method comparison and selection tool developed from a comprehensive literature review, the research team's extensive expertise and inputs from potential users. Twenty-eight different methods were identified, characterised by their relevance to different application areas, project life cycle stages, types of output and levels of insight, and four input resources required (time, money, knowledge and data). The characterisation is presented in matrix forms to allow quick comparison and selection. This paper also highlights significant knowledge gaps in the existing literature when assessing the applicability of particular approaches to health services management, where modelling and simulation skills are scarce let alone money and time. A modelling and simulation method comparison and selection tool is developed to assist with the selection of methods appropriate to supporting specific decision making processes. In particular it addresses the issue of which method is most appropriate to which specific health services management problem, what the user might expect to be obtained from the method, and what is required to use the method. In summary, we believe the tool adds value to the scarce existing literature on methods comparison and selection.

A velocity-correction projection method based immersed boundary method for incompressible flows

NASA Astrophysics Data System (ADS)

Cai, Shanggui

2014-11-01

In the present work we propose a novel direct forcing immersed boundary method based on the velocity-correction projection method of [J.L. Guermond, J. Shen, Velocity-correction projection methods for incompressible flows, SIAM J. Numer. Anal., 41 (1)(2003) 112]. The principal idea of immersed boundary method is to correct the velocity in the vicinity of the immersed object by using an artificial force to mimic the presence of the physical boundaries. Therefore, velocity-correction projection method is preferred to its pressure-correction counterpart in the present work. Since the velocity-correct projection method is considered as a dual class of pressure-correction method, the proposed method here can also be interpreted in the way that first the pressure is predicted by treating the viscous term explicitly without the consideration of the immersed boundary, and the solenoidal velocity is used to determine the volume force on the Lagrangian points, then the non-slip boundary condition is enforced by correcting the velocity with the implicit viscous term. To demonstrate the efficiency and accuracy of the proposed method, several numerical simulations are performed and compared with the results in the literature. China Scholarship Council.

Approaches to Mixed Methods Dissemination and Implementation Research: Methods, Strengths, Caveats, and Opportunities.

PubMed

Green, Carla A; Duan, Naihua; Gibbons, Robert D; Hoagwood, Kimberly E; Palinkas, Lawrence A; Wisdom, Jennifer P

2015-09-01

Limited translation of research into practice has prompted study of diffusion and implementation, and development of effective methods of encouraging adoption, dissemination and implementation. Mixed methods techniques offer approaches for assessing and addressing processes affecting implementation of evidence-based interventions. We describe common mixed methods approaches used in dissemination and implementation research, discuss strengths and limitations of mixed methods approaches to data collection, and suggest promising methods not yet widely used in implementation research. We review qualitative, quantitative, and hybrid approaches to mixed methods dissemination and implementation studies, and describe methods for integrating multiple methods to increase depth of understanding while improving reliability and validity of findings.

Approaches to Mixed Methods Dissemination and Implementation Research: Methods, Strengths, Caveats, and Opportunities

PubMed Central

Green, Carla A.; Duan, Naihua; Gibbons, Robert D.; Hoagwood, Kimberly E.; Palinkas, Lawrence A.; Wisdom, Jennifer P.

2015-01-01

Limited translation of research into practice has prompted study of diffusion and implementation, and development of effective methods of encouraging adoption, dissemination and implementation. Mixed methods techniques offer approaches for assessing and addressing processes affecting implementation of evidence-based interventions. We describe common mixed methods approaches used in dissemination and implementation research, discuss strengths and limitations of mixed methods approaches to data collection, and suggest promising methods not yet widely used in implementation research. We review qualitative, quantitative, and hybrid approaches to mixed methods dissemination and implementation studies, and describe methods for integrating multiple methods to increase depth of understanding while improving reliability and validity of findings. PMID:24722814

Methods of Farm Guidance

ERIC Educational Resources Information Center

Vir, Dharm

1971-01-01

A survey of teaching methods for farm guidance workers in India, outlining some approaches developed by and used in other nations. Discusses mass educational methods, group educational methods, and the local leadership method. (JB)

Project Method, as One of the Basic Methods of Environmental Education

ERIC Educational Resources Information Center

Szállassy, Noémi

2008-01-01

Our aim was to present in this paper the one of the most important methods of environmental education, the project method. We present here the steps and phases of project method and we give an example of how to use these elements in planning an activity for celebrating the World Day for Water.

Research Methods

DTIC Science & Technology

1992-01-01

cognitive function. For example. physiological methods allow for visual sensitivity measurements in infants and children with about the same level of...potential (ERP), the event-related magnetic field (ERF), and pupillometry . Where possible, we cite specific experiments that deal with display or stimulus...technical barrier preventing the application of these methods to the analysis of human performance with color displays. Pupillometry . The pupillary

Parallelization of the FLAPW method and comparison with the PPW method

NASA Astrophysics Data System (ADS)

Canning, Andrew; Mannstadt, Wolfgang; Freeman, Arthur

2000-03-01

The FLAPW (full-potential linearized-augmented plane-wave) method is one of the most accurate first-principles methods for determining electronic and magnetic properties of crystals and surfaces. In the past the FLAPW method has been limited to systems of about a hundred atoms due to the lack of an efficient parallel implementation to exploit the power and memory of parallel computers. In this work we present an efficient parallelization of the method by division among the processors of the plane-wave components for each state. The code is also optimized for RISC (reduced instruction set computer) architectures, such as those found on most parallel computers, making full use of BLAS (basic linear algebra subprograms) wherever possible. Scaling results are presented for systems of up to 686 silicon atoms and 343 palladium atoms per unit cell running on up to 512 processors on a Cray T3E parallel supercomputer. Some results will also be presented on a comparison of the plane-wave pseudopotential method and the FLAPW method on large systems.

An Improved Newton's Method.

ERIC Educational Resources Information Center

Mathews, John H.

1989-01-01

Describes Newton's method to locate roots of an equation using the Newton-Raphson iteration formula. Develops an adaptive method overcoming limitations of the iteration method. Provides the algorithm and computer program of the adaptive Newton-Raphson method. (YP)

FPGA Implementation of the Coupled Filtering Method and the Affine Warping Method.

PubMed

Zhang, Chen; Liang, Tianzhu; Mok, Philip K T; Yu, Weichuan

2017-07-01

In ultrasound image analysis, the speckle tracking methods are widely applied to study the elasticity of body tissue. However, "feature-motion decorrelation" still remains as a challenge for the speckle tracking methods. Recently, a coupled filtering method and an affine warping method were proposed to accurately estimate strain values, when the tissue deformation is large. The major drawback of these methods is the high computational complexity. Even the graphics processing unit (GPU)-based program requires a long time to finish the analysis. In this paper, we propose field-programmable gate array (FPGA)-based implementations of both methods for further acceleration. The capability of FPGAs on handling different image processing components in these methods is discussed. A fast and memory-saving image warping approach is proposed. The algorithms are reformulated to build a highly efficient pipeline on FPGA. The final implementations on a Xilinx Virtex-7 FPGA are at least 13 times faster than the GPU implementation on the NVIDIA graphic card (GeForce GTX 580).

Methods for assessing geodiversity

NASA Astrophysics Data System (ADS)

Zwoliński, Zbigniew; Najwer, Alicja; Giardino, Marco

2017-04-01

The accepted systematics of geodiversity assessment methods will be presented in three categories: qualitative, quantitative and qualitative-quantitative. Qualitative methods are usually descriptive methods that are suited to nominal and ordinal data. Quantitative methods use a different set of parameters and indicators to determine the characteristics of geodiversity in the area being researched. Qualitative-quantitative methods are a good combination of the collection of quantitative data (i.e. digital) and cause-effect data (i.e. relational and explanatory). It seems that at the current stage of the development of geodiversity research methods, qualitative-quantitative methods are the most advanced and best assess the geodiversity of the study area. Their particular advantage is the integration of data from different sources and with different substantive content. Among the distinguishing features of the quantitative and qualitative-quantitative methods for assessing geodiversity are their wide use within geographic information systems, both at the stage of data collection and data integration, as well as numerical processing and their presentation. The unresolved problem for these methods, however, is the possibility of their validation. It seems that currently the best method of validation is direct filed confrontation. Looking to the next few years, the development of qualitative-quantitative methods connected with cognitive issues should be expected, oriented towards ontology and the Semantic Web.

The Misgav Ladach method for cesarean section compared to the Pfannenstiel method.

PubMed

Darj, E; Nordström, M L

1999-01-01

The aim of the study was to evaluate the outcome of two different methods of cesarean section (CS). The study was designed as a prospective, randomized, controlled trial. All CS were performed at the University Hospital in Uppsala, Sweden. Fifty women admitted to hospital for a first elective CS were consecutively included in the study. They were randomly allocated to two groups. One group was operated on by the Misgav Ladach method for CS and the other group by the Pfannenstiel method. All operations were performed by the same surgeon. Duration of operation, amount of bleeding, analgesics required, scar appearance and length of hospitalization. Operating time was significantly different between the two methods, with an average of 12.5 minutes with the Misgav Ladach method and 26 minutes with the Pfannenstiel method (p<0.001). The amount of blood loss differed significantly, with 448 ml and 608 ml respectively (p=0.017). Significantly less analgesic injections and tablets (p=0.004) were needed after the Misgav Ladach method. The Misgav Ladach method of CS has advantages over the Pfannenstiel method by being significantly quicker to perform, with a reduced amount of bleeding and diminished postoperative pain. The women were satisfied with the appearance of their scars. In this study no negative effects of the new operation technique were discovered.

[ANTHROPOMETRIC PROPORTIONALITY METHOD ELECTION IN A SPORT POPULATION; COMPARISON OF THREE METHODS].

PubMed

Almagià, Atilio; Araneda, Alberto; Sánchez, Javier; Sánchez, Patricio; Zúñiga, Maximiliano; Plaza, Paula

2015-09-01

the proportionality model application, based on ideal proportions, would have a great impact on high performance sports, due to best athletes to resemble anthropometrically. the objective of this study was to compare the following anthropometric methods of proportionality: Phantom, Combined and Scalable, in male champion university Chilean soccer players in 2012 and 2013, using South American professional soccer players as criterion, in order to find the most appropriate proportionality method to sports populations. the measerement of 22 kinanthropometric variables was performed, according to the ISAK protocol, to a sample constituted of 13 members of the men's soccer team of the Pontificia Universidad Católica de Valparaíso. The Z-values of the anthropometrics variables of each method were obtained using their respective equations. It was used as criterion population South American soccer players. a similar trend was observed between the three methods. Significant differences (p < 0.05) were found in some Z-values of Scalable and Combined methods compared to Phantom method. No significant differences were observed between the results obtained by the Combined and Scalable methods, except in wrist, thigh and hip perimeters. it is more appropriate to use the Scalable method over the Combined and Phantom methods for the comparison of Z values in kinanthropometric variables in athletes of the same discipline. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

Mixed methods research.

PubMed

Halcomb, Elizabeth; Hickman, Louise

2015-04-08

Mixed methods research involves the use of qualitative and quantitative data in a single research project. It represents an alternative methodological approach, combining qualitative and quantitative research approaches, which enables nurse researchers to explore complex phenomena in detail. This article provides a practical overview of mixed methods research and its application in nursing, to guide the novice researcher considering a mixed methods research project.

[Theory, method and application of method R on estimation of (co)variance components].

PubMed

Liu, Wen-Zhong

2004-07-01

Theory, method and application of Method R on estimation of (co)variance components were reviewed in order to make the method be reasonably used. Estimation requires R values,which are regressions of predicted random effects that are calculated using complete dataset on predicted random effects that are calculated using random subsets of the same data. By using multivariate iteration algorithm based on a transformation matrix,and combining with the preconditioned conjugate gradient to solve the mixed model equations, the computation efficiency of Method R is much improved. Method R is computationally inexpensive,and the sampling errors and approximate credible intervals of estimates can be obtained. Disadvantages of Method R include a larger sampling variance than other methods for the same data,and biased estimates in small datasets. As an alternative method, Method R can be used in larger datasets. It is necessary to study its theoretical properties and broaden its application range further.

Recent Advances in the Method of Forces: Integrated Force Method of Structural Analysis

NASA Technical Reports Server (NTRS)

Patnaik, Surya N.; Coroneos, Rula M.; Hopkins, Dale A.

1998-01-01

Stress that can be induced in an elastic continuum can be determined directly through the simultaneous application of the equilibrium equations and the compatibility conditions. In the literature, this direct stress formulation is referred to as the integrated force method. This method, which uses forces as the primary unknowns, complements the popular equilibrium-based stiffness method, which considers displacements as the unknowns. The integrated force method produces accurate stress, displacement, and frequency results even for modest finite element models. This version of the force method should be developed as an alternative to the stiffness method because the latter method, which has been researched for the past several decades, may have entered its developmental plateau. Stress plays a primary role in the development of aerospace and other products, and its analysis is difficult. Therefore, it is advisable to use both methods to calculate stress and eliminate errors through comparison. This paper examines the role of the integrated force method in analysis, animation and design.

A New Method for Extubation: Comparison between Conventional and New Methods.

PubMed

Yousefshahi, Fardin; Barkhordari, Khosro; Movafegh, Ali; Tavakoli, Vida; Paknejad, Omalbanin; Bina, Payvand; Yousefshahi, Hadi; Sheikh Fathollahi, Mahmood

2012-08-01

Extubation is associated with the risk of complications such as accumulated secretion above the endotracheal tube cuff, eventual atelectasia following a reduction in pulmonary volumes because of a lack of physiological positive end expiratory pressure, and intra-tracheal suction. In order to reduce these complications, and, based on basic physiological principles, a new practical extubation method is presented in this article. The study was designed as a six-month prospective cross-sectional clinical trial. Two hundred fifty-seven patients undergoing coronary artery bypass grafting (CABG) were divided into two groups based on their scheduled surgery time. The first group underwent the conventional extubation method, while the other group was extubated according to a new described method. Arterial blood gas (ABG) analysis results before and after extubation were compared between the two groups to find the effect of the extubation method on the ABG parameters and the oxygenation profile. In all time intervals, the partial pressure of oxygen in arterial blood / fraction of inspired oxygen (PaO(2)/FiO(2)) ratio in the new method group patients was improved compared to that in the conventional method; some differences, like PaO(2)/FiO(2) four hours after extubation, were statistically significant, however (p value=0.0063). The new extubation method improved some respiratory parameters and thus attenuated oxygenation complications and amplified oxygenation after extubation.

Formal Methods Tool Qualification

NASA Technical Reports Server (NTRS)

Wagner, Lucas G.; Cofer, Darren; Slind, Konrad; Tinelli, Cesare; Mebsout, Alain

2017-01-01

Formal methods tools have been shown to be effective at finding defects in safety-critical digital systems including avionics systems. The publication of DO-178C and the accompanying formal methods supplement DO-333 allows applicants to obtain certification credit for the use of formal methods without providing justification for them as an alternative method. This project conducted an extensive study of existing formal methods tools, identifying obstacles to their qualification and proposing mitigations for those obstacles. Further, it interprets the qualification guidance for existing formal methods tools and provides case study examples for open source tools. This project also investigates the feasibility of verifying formal methods tools by generating proof certificates which capture proof of the formal methods tool's claim, which can be checked by an independent, proof certificate checking tool. Finally, the project investigates the feasibility of qualifying this proof certificate checker, in the DO-330 framework, in lieu of qualifying the model checker itself.

Electrodeionization method

DOEpatents

Lin, YuPo J.; Hestekin, Jamie; Arora, Michelle; St. Martin, Edward J.

2004-09-28

An electrodeionization method for continuously producing and or separating and/or concentrating ionizable organics present in dilute concentrations in an ionic solution while controlling the pH to within one to one-half pH unit method for continuously producing and or separating and/or concentrating ionizable organics present in dilute concentrations in an ionic solution while controlling the pH to within one to one-half pH unit.

A new method named as Segment-Compound method of baffle design

NASA Astrophysics Data System (ADS)

Qin, Xing; Yang, Xiaoxu; Gao, Xin; Liu, Xishuang

2017-02-01

As the observation demand increased, the demand of the lens imaging quality rising. Segment- Compound baffle design method was proposed in this paper. Three traditional methods of baffle design they are characterized as Inside to Outside, Outside to Inside, and Mirror Symmetry. Through a transmission type of optical system, the four methods were used to design stray light suppression structure for it, respectively. Then, structures modeling simulation with Solidworks, CAXA, Tracepro, At last, point source transmittance (PST) curve lines were got to describe their performance. The result shows that the Segment- Compound method can inhibit stay light more effectively. Moreover, it is easy to active and without use special material.

Semi top-down method combined with earth-bank, an effective method for basement construction.

NASA Astrophysics Data System (ADS)

Tuan, B. Q.; Tam, Ng M.

2018-04-01

Choosing an appropriate method of deep excavation not only plays a decisive role in technical success, but also in economics of the construction project. Presently, we mainly base on to key methods: “Bottom-up” and “Top-down” construction method. Right now, this paper presents an another method of construction that is “Semi Top-down method combining with earth-bank” in order to take the advantages and limit the weakness of the above methods. The Bottom-up method was improved by using the earth-bank to stabilize retaining walls instead of the bracing steel struts. The Top-down method was improved by using the open cut method for the half of the earthwork quantities.

Metrics in method engineering

NASA Astrophysics Data System (ADS)

Brinkkemper, S.; Rossi, M.

1994-12-01

As customizable computer aided software engineering (CASE) tools, or CASE shells, have been introduced in academia and industry, there has been a growing interest into the systematic construction of methods and their support environments, i.e. method engineering. To aid the method developers and method selectors in their tasks, we propose two sets of metrics, which measure the complexity of diagrammatic specification techniques on the one hand, and of complete systems development methods on the other hand. Proposed metrics provide a relatively fast and simple way to analyze the technique (or method) properties, and when accompanied with other selection criteria, can be used for estimating the cost of learning the technique and the relative complexity of a technique compared to others. To demonstrate the applicability of the proposed metrics, we have applied them to 34 techniques and 15 methods.

Micro/nano moire methods

NASA Astrophysics Data System (ADS)

Asundi, Anand K.; Shang, Haixia; Xie, Huimin; Li, Biao

2003-10-01

Two novel micro/nano moire method, SEM scanning moiré and AFM scanning moire techniques are discussed in this paper. The principle and applications of two scanning moire methods are described in detail. The residual deformation in a polysilicon MEMS cantilever structure with a 5000 lines/mm grating after removing the SiO2 sacrificial layer is accurately measured by SEM scanning moire method. While AFM scanning moire method is used to detect thermal deformation of electronic package components, and formation of nano-moire on a freshly cleaved mica crystal. Experimental results demonstrate the feasibility of these two moire methods, and also show they are effective methods to measure the deformation from micron to nano-scales.

[Medical Equipment Maintenance Methods].

PubMed

Liu, Hongbin

2015-09-01

Due to the high technology and the complexity of medical equipment, as well as to the safety and effectiveness, it determines the high requirements of the medical equipment maintenance work. This paper introduces some basic methods of medical instrument maintenance, including fault tree analysis, node method and exclusive method which are the three important methods in the medical equipment maintenance, through using these three methods for the instruments that have circuit drawings, hardware breakdown maintenance can be done easily. And this paper introduces the processing methods of some special fault conditions, in order to reduce little detours in meeting the same problems. Learning is very important for stuff just engaged in this area.

SAM Methods Query

EPA Pesticide Factsheets

Laboratories measuring target chemical, radiochemical, pathogens, and biotoxin analytes in environmental samples can use this online query tool to identify analytical methods included in EPA's Selected Analytical Methods for Environmental Remediation

A Hybrid Method for Pancreas Extraction from CT Image Based on Level Set Methods

PubMed Central

Tan, Hanqing; Fujita, Hiroshi

2013-01-01

This paper proposes a novel semiautomatic method to extract the pancreas from abdominal CT images. Traditional level set and region growing methods that request locating initial contour near the final boundary of object have problem of leakage to nearby tissues of pancreas region. The proposed method consists of a customized fast-marching level set method which generates an optimal initial pancreas region to solve the problem that the level set method is sensitive to the initial contour location and a modified distance regularized level set method which extracts accurate pancreas. The novelty in our method is the proper selection and combination of level set methods, furthermore an energy-decrement algorithm and an energy-tune algorithm are proposed to reduce the negative impact of bonding force caused by connected tissue whose intensity is similar with pancreas. As a result, our method overcomes the shortages of oversegmentation at weak boundary and can accurately extract pancreas from CT images. The proposed method is compared to other five state-of-the-art medical image segmentation methods based on a CT image dataset which contains abdominal images from 10 patients. The evaluated results demonstrate that our method outperforms other methods by achieving higher accuracy and making less false segmentation in pancreas extraction. PMID:24066016

Krylov subspace iterative methods for boundary element method based near-field acoustic holography.

PubMed

Valdivia, Nicolas; Williams, Earl G

2005-02-01

The reconstruction of the acoustic field for general surfaces is obtained from the solution of a matrix system that results from a boundary integral equation discretized using boundary element methods. The solution to the resultant matrix system is obtained using iterative regularization methods that counteract the effect of noise on the measurements. These methods will not require the calculation of the singular value decomposition, which can be expensive when the matrix system is considerably large. Krylov subspace methods are iterative methods that have the phenomena known as "semi-convergence," i.e., the optimal regularization solution is obtained after a few iterations. If the iteration is not stopped, the method converges to a solution that generally is totally corrupted by errors on the measurements. For these methods the number of iterations play the role of the regularization parameter. We will focus our attention to the study of the regularizing properties from the Krylov subspace methods like conjugate gradients, least squares QR and the recently proposed Hybrid method. A discussion and comparison of the available stopping rules will be included. A vibrating plate is considered as an example to validate our results.

An extended Lagrangian method

NASA Technical Reports Server (NTRS)

Liou, Meng-Sing

1992-01-01

A unique formulation of describing fluid motion is presented. The method, referred to as 'extended Lagrangian method', is interesting from both theoretical and numerical points of view. The formulation offers accuracy in numerical solution by avoiding numerical diffusion resulting from mixing of fluxes in the Eulerian description. Meanwhile, it also avoids the inaccuracy incurred due to geometry and variable interpolations used by the previous Lagrangian methods. Unlike the Lagrangian method previously imposed which is valid only for supersonic flows, the present method is general and capable of treating subsonic flows as well as supersonic flows. The method proposed in this paper is robust and stable. It automatically adapts to flow features without resorting to clustering, thereby maintaining rather uniform grid spacing throughout and large time step. Moreover, the method is shown to resolve multi-dimensional discontinuities with a high level of accuracy, similar to that found in one-dimensional problems.

Decentralized Quasi-Newton Methods

NASA Astrophysics Data System (ADS)

Eisen, Mark; Mokhtari, Aryan; Ribeiro, Alejandro

2017-05-01

We introduce the decentralized Broyden-Fletcher-Goldfarb-Shanno (D-BFGS) method as a variation of the BFGS quasi-Newton method for solving decentralized optimization problems. The D-BFGS method is of interest in problems that are not well conditioned, making first order decentralized methods ineffective, and in which second order information is not readily available, making second order decentralized methods impossible. D-BFGS is a fully distributed algorithm in which nodes approximate curvature information of themselves and their neighbors through the satisfaction of a secant condition. We additionally provide a formulation of the algorithm in asynchronous settings. Convergence of D-BFGS is established formally in both the synchronous and asynchronous settings and strong performance advantages relative to first order methods are shown numerically.

The ICARE Method

NASA Technical Reports Server (NTRS)

Henke, Luke

2010-01-01

The ICARE method is a flexible, widely applicable method for systems engineers to solve problems and resolve issues in a complete and comprehensive manner. The method can be tailored by diverse users for direct application to their function (e.g. system integrators, design engineers, technical discipline leads, analysts, etc.). The clever acronym, ICARE, instills the attitude of accountability, safety, technical rigor and engagement in the problem resolution: Identify, Communicate, Assess, Report, Execute (ICARE). This method was developed through observation of Space Shuttle Propulsion Systems Engineering and Integration (PSE&I) office personnel approach in an attempt to succinctly describe the actions of an effective systems engineer. Additionally it evolved from an effort to make a broadly-defined checklist for a PSE&I worker to perform their responsibilities in an iterative and recursive manner. The National Aeronautics and Space Administration (NASA) Systems Engineering Handbook states, engineering of NASA systems requires a systematic and disciplined set of processes that are applied recursively and iteratively for the design, development, operation, maintenance, and closeout of systems throughout the life cycle of the programs and projects. ICARE is a method that can be applied within the boundaries and requirements of NASA s systems engineering set of processes to provide an elevated sense of duty and responsibility to crew and vehicle safety. The importance of a disciplined set of processes and a safety-conscious mindset increases with the complexity of the system. Moreover, the larger the system and the larger the workforce, the more important it is to encourage the usage of the ICARE method as widely as possible. According to the NASA Systems Engineering Handbook, elements of a system can include people, hardware, software, facilities, policies and documents; all things required to produce system-level results, qualities, properties, characteristics

Estimating parameter of Rayleigh distribution by using Maximum Likelihood method and Bayes method

NASA Astrophysics Data System (ADS)

Ardianti, Fitri; Sutarman

2018-01-01

In this paper, we use Maximum Likelihood estimation and Bayes method under some risk function to estimate parameter of Rayleigh distribution to know the best method. The prior knowledge which used in Bayes method is Jeffrey’s non-informative prior. Maximum likelihood estimation and Bayes method under precautionary loss function, entropy loss function, loss function-L 1 will be compared. We compare these methods by bias and MSE value using R program. After that, the result will be displayed in tables to facilitate the comparisons.

Multigrid contact detection method

NASA Astrophysics Data System (ADS)

He, Kejing; Dong, Shoubin; Zhou, Zhaoyao

2007-03-01

Contact detection is a general problem of many physical simulations. This work presents a O(N) multigrid method for general contact detection problems (MGCD). The multigrid idea is integrated with contact detection problems. Both the time complexity and memory consumption of the MGCD are O(N) . Unlike other methods, whose efficiencies are influenced strongly by the object size distribution, the performance of MGCD is insensitive to the object size distribution. We compare the MGCD with the no binary search (NBS) method and the multilevel boxing method in three dimensions for both time complexity and memory consumption. For objects with similar size, the MGCD is as good as the NBS method, both of which outperform the multilevel boxing method regarding memory consumption. For objects with diverse size, the MGCD outperform both the NBS method and the multilevel boxing method. We use the MGCD to solve the contact detection problem for a granular simulation system based on the discrete element method. From this granular simulation, we get the density property of monosize packing and binary packing with size ratio equal to 10. The packing density for monosize particles is 0.636. For binary packing with size ratio equal to 10, when the number of small particles is 300 times as the number of big particles, the maximal packing density 0.824 is achieved.

Adaptive Monte Carlo methods

NASA Astrophysics Data System (ADS)

Fasnacht, Marc

We develop adaptive Monte Carlo methods for the calculation of the free energy as a function of a parameter of interest. The methods presented are particularly well-suited for systems with complex energy landscapes, where standard sampling techniques have difficulties. The Adaptive Histogram Method uses a biasing potential derived from histograms recorded during the simulation to achieve uniform sampling in the parameter of interest. The Adaptive Integration method directly calculates an estimate of the free energy from the average derivative of the Hamiltonian with respect to the parameter of interest and uses it as a biasing potential. We compare both methods to a state of the art method, and demonstrate that they compare favorably for the calculation of potentials of mean force of dense Lennard-Jones fluids. We use the Adaptive Integration Method to calculate accurate potentials of mean force for different types of simple particles in a Lennard-Jones fluid. Our approach allows us to separate the contributions of the solvent to the potential of mean force from the effect of the direct interaction between the particles. With contributions of the solvent determined, we can find the potential of mean force directly for any other direct interaction without additional simulations. We also test the accuracy of the Adaptive Integration Method on a thermodynamic cycle, which allows us to perform a consistency check between potentials of mean force and chemical potentials calculated using the Adaptive Integration Method. The results demonstrate a high degree of consistency of the method.

Numerical methods in acoustics

NASA Astrophysics Data System (ADS)

Candel, S. M.

This paper presents a survey of some computational techniques applicable to acoustic wave problems. Recent advances in wave extrapolation methods, spectral methods and boundary integral methods are discussed and illustrated by specific calculations.

Pesticide Analytical Methods

EPA Pesticide Factsheets

Pesticide manufacturers must develop and submit analytical methods for their pesticide products to support registration of their products under FIFRA. Learn about these methods as well as SOPs for testing of antimicrobial products against three organisms.

Inexact adaptive Newton methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bertiger, W.I.; Kelsey, F.J.

1985-02-01

The Inexact Adaptive Newton method (IAN) is a modification of the Adaptive Implicit Method/sup 1/ (AIM) with improved Newton convergence. Both methods simplify the Jacobian at each time step by zeroing coefficients in regions where saturations are changing slowly. The methods differ in how the diagonal block terms are treated. On test problems with up to 3,000 cells, IAN consistently saves approximately 30% of the CPU time when compared to the fully implicit method. AIM shows similar savings on some problems, but takes as much CPU time as fully implicit on other test problems due to poor Newton convergence.

Methods That Matter: Integrating Mixed Methods for More Effective Social Science Research

ERIC Educational Resources Information Center

Hay, M. Cameron, Ed.

2016-01-01

To do research that really makes a difference--the authors of this book argue--social scientists need questions and methods that reflect the complexity of the world. Bringing together a consortium of voices across a variety of fields, "Methods that Matter" offers compelling and successful examples of mixed methods research that do just…

Nanotube structures, methods of making nanotube structures, and methods of accessing intracellular space

DOEpatents

VanDersarl, Jules J.; Xu, Alexander M.; Melosh, Nicholas A.; Tayebi, Noureddine

2016-02-23

In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in one aspect, relate to methods of making a structure including nanotubes, a structure including nanotubes, methods of delivering a fluid to a cell, methods of removing a fluid to a cell, methods of accessing intracellular space, and the like.

Ignitability test method

NASA Technical Reports Server (NTRS)

Bement, Laurence J.; Schimmel, Morry L.

1989-01-01

To overcome serious weaknesses in determining the performance of initiating devices, a novel 'ignitability test method', representing actual design interfaces and ignition materials, has been developed. Ignition device output consists of heat, light, gas an burning particles. Past research methods have evaluated these parameters individually. This paper describes the development and demonstration of an ignitability test method combining all these parameters, and the quantitative assessment of the ignition performance of two widely used percussion primers, the M42C1-PA101 and the M42C2-793. The ignition materials used for this evaluation were several powder, granule and pellet sizes of black powder and boron-potassium nitrate. This test method should be useful for performance evaluation of all initiator types, quality assurance, evaluation of ignition interfaces, and service life studies of initiators and ignition materials.

Catalytic reforming methods

DOEpatents

Tadd, Andrew R; Schwank, Johannes

2013-05-14

A catalytic reforming method is disclosed herein. The method includes sequentially supplying a plurality of feedstocks of variable compositions to a reformer. The method further includes adding a respective predetermined co-reactant to each of the plurality of feedstocks to obtain a substantially constant output from the reformer for the plurality of feedstocks. The respective predetermined co-reactant is based on a C/H/O atomic composition for a respective one of the plurality of feedstocks and a predetermined C/H/O atomic composition for the substantially constant output.

An Extended Lagrangian Method

NASA Technical Reports Server (NTRS)

Liou, Meng-Sing

1995-01-01

A unique formulation of describing fluid motion is presented. The method, referred to as 'extended Lagrangian method,' is interesting from both theoretical and numerical points of view. The formulation offers accuracy in numerical solution by avoiding numerical diffusion resulting from mixing of fluxes in the Eulerian description. The present method and the Arbitrary Lagrangian-Eulerian (ALE) method have a similarity in spirit-eliminating the cross-streamline numerical diffusion. For this purpose, we suggest a simple grid constraint condition and utilize an accurate discretization procedure. This grid constraint is only applied to the transverse cell face parallel to the local stream velocity, and hence our method for the steady state problems naturally reduces to the streamline-curvature method, without explicitly solving the steady stream-coordinate equations formulated a priori. Unlike the Lagrangian method proposed by Loh and Hui which is valid only for steady supersonic flows, the present method is general and capable of treating subsonic flows and supersonic flows as well as unsteady flows, simply by invoking in the same code an appropriate grid constraint suggested in this paper. The approach is found to be robust and stable. It automatically adapts to flow features without resorting to clustering, thereby maintaining rather uniform grid spacing throughout and large time step. Moreover, the method is shown to resolve multi-dimensional discontinuities with a high level of accuracy, similar to that found in one-dimensional problems.

Capital investment analysis: three methods.

PubMed

Gapenski, L C

1993-08-01

Three cash flow/discount rate methods can be used when conducting capital budgeting financial analyses: the net operating cash flow method, the net cash flow to investors method, and the net cash flow to equity holders method. The three methods differ in how the financing mix and the benefits of debt financing are incorporated. This article explains the three methods, demonstrates that they are essentially equivalent, and recommends which method to use under specific circumstances.

Single-Case Designs and Qualitative Methods: Applying a Mixed Methods Research Perspective

ERIC Educational Resources Information Center

Hitchcock, John H.; Nastasi, Bonnie K.; Summerville, Meredith

2010-01-01

The purpose of this conceptual paper is to describe a design that mixes single-case (sometimes referred to as single-subject) and qualitative methods, hereafter referred to as a single-case mixed methods design (SCD-MM). Minimal attention has been given to the topic of applying qualitative methods to SCD work in the literature. These two…

An extended Lagrangian method

NASA Technical Reports Server (NTRS)

Liou, Meng-Sing

1993-01-01

A unique formulation of describing fluid motion is presented. The method, referred to as 'extended Lagrangian method', is interesting from both theoretical and numerical points of view. The formulation offers accuracy in numerical solution by avoiding numerical diffusion resulting from mixing of fluxes in the Eulerian description. Meanwhile, it also avoids the inaccuracy incurred due to geometry and variable interpolations used by the previous Lagrangian methods. The present method is general and capable of treating subsonic flows as well as supersonic flows. The method proposed in this paper is robust and stable. It automatically adapts to flow features without resorting to clustering, thereby maintaining rather uniform grid spacing throughout and large time step. Moreover, the method is shown to resolve multidimensional discontinuities with a high level of accuracy, similar to that found in 1D problems.

Evaluating marginal likelihood with thermodynamic integration method and comparison with several other numerical methods

DOE PAGES

Liu, Peigui; Elshall, Ahmed S.; Ye, Ming; ...

2016-02-05

Evaluating marginal likelihood is the most critical and computationally expensive task, when conducting Bayesian model averaging to quantify parametric and model uncertainties. The evaluation is commonly done by using Laplace approximations to evaluate semianalytical expressions of the marginal likelihood or by using Monte Carlo (MC) methods to evaluate arithmetic or harmonic mean of a joint likelihood function. This study introduces a new MC method, i.e., thermodynamic integration, which has not been attempted in environmental modeling. Instead of using samples only from prior parameter space (as in arithmetic mean evaluation) or posterior parameter space (as in harmonic mean evaluation), the thermodynamicmore » integration method uses samples generated gradually from the prior to posterior parameter space. This is done through a path sampling that conducts Markov chain Monte Carlo simulation with different power coefficient values applied to the joint likelihood function. The thermodynamic integration method is evaluated using three analytical functions by comparing the method with two variants of the Laplace approximation method and three MC methods, including the nested sampling method that is recently introduced into environmental modeling. The thermodynamic integration method outperforms the other methods in terms of their accuracy, convergence, and consistency. The thermodynamic integration method is also applied to a synthetic case of groundwater modeling with four alternative models. The application shows that model probabilities obtained using the thermodynamic integration method improves predictive performance of Bayesian model averaging. As a result, the thermodynamic integration method is mathematically rigorous, and its MC implementation is computationally general for a wide range of environmental problems.« less

Topics in spectral methods

NASA Technical Reports Server (NTRS)

Gottlieb, D.; Turkel, E.

1985-01-01

After detailing the construction of spectral approximations to time-dependent mixed initial boundary value problems, a study is conducted of differential equations of the form 'partial derivative of u/partial derivative of t = Lu + f', where for each t, u(t) belongs to a Hilbert space such that u satisfies homogeneous boundary conditions. For the sake of simplicity, it is assumed that L is an unbounded, time-independent linear operator. Attention is given to Fourier methods of both Galerkin and pseudospectral method types, the Galerkin method, the pseudospectral Chebyshev and Legendre methods, the error equation, hyperbolic partial differentiation equations, and time discretization and iterative methods.

A rapid method for soil cement design : Louisiana slope value method.

DOT National Transportation Integrated Search

1964-03-01

The current procedure used by the Louisiana Department of Highways for laboratory design of cement stabilized soil base and subbase courses is taken from standard AASHO test methods, patterned after Portland Cement Association criteria. These methods...

The Misgav Ladach method for cesarean section: method description.

PubMed

Holmgren, G; Sjöholm, L; Stark, M

1999-08-01

A method description is given for the Misgav Ladach method for cesarean section. This is based on the Joel-Cohen incision originally introduced for hysterectomy. The incision is a straight transverse incision somewhat higher than the Pfannenstiel incision. The subcutaneous tissue is left undisturbed apart from the midline. The rectus sheath is separated along its fibres. The rectus muscles are separated by pulling. The peritoneum is opened by stretching with index fingers. The uterus is opened with an index finger and the hole enlarged between the index finger of one hand and the thumb on the other. The uterus is closed with a one-layer continuous locking stitch. The visceral and parietal peritoneal layers are left open. The rectus muscle is not stitched. The rectus sheath is stitched with a continuous non-locking stitch. The skin is closed with two or three mattress sutures. The space in between is apposed with non-traumatic forceps for 5 minutes. The basic philosophy is to work in harmony with the body's anatomy and physiology and not against them. The method is restrictive in the use of sharp instruments, preferring manual manipulation. The method gives quicker recovery, less use of post-operative antibiotics, antifebrile medicines and analgesics. There is a shorter anesthetic and shorter working time for the operative team. It is suitable for both emergency and planned operations.

Sand consolidation method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Young, B.M.

1965-10-05

This is a new and improved sand consolidation method wherein an in-situ curing of a resinous fluid is undertaken. This method does not require that the resinous fluids be catalyzed at the surface of the well or well bore as is the case in previous methods. This method consists of, first, pumping an acid-curable consolidating fluid into the unconsolidated sand or earth formation and, secondly, pumping an oil overflush solution containing a halogenated organic or other organic acid or delayed acid-producing chemical. A small quantity of diesel oilspacer may be used between the plastic catalyst solution. The overflush functions tomore » remove permeability, and its acid or acid producing component promotes subsequent hardening of the remaining film of consolidating fluid. Trichloroacetic acid and benzotrichloride are satisfactory to add to the overflush solution for curing the resins. (17 claims)« less

[Principle of LAMP method--a simple and rapid gene amplification method].

PubMed

Ushikubo, Hiroshi

2004-06-01

So far nucleic acid test (NAT) has been employed in various fields, including infectious disease diagnoses. However, due to its complicated procedures and relatively high cost, it has not been widely utilized in many actual diagnostic applications. We have therefore developed a simple and rapid gene amplification technology, Loop-mediated Isothermal Amplification (LAMP) method, which has shown prominent results of surpassing the performance of the conventional gene amplification methods. LAMP method acquires three main features: (1) all reaction can be carried out under isothermal conditions; (2) the amplification efficiency is extremely high and tremendous amount of amplification products can be obtained; and (3) the reaction is highly specific. Furthermore, developed from the standard LAMP method, a rapid LAMP method, by adding in the loop primers, can reduce the amplification time from the previous 1 hour to less than 30 minutes. Enormous amount of white precipitate of magnesium pyrophosphate is produced as a by-product of the amplification, therefore, direct visual detection is possible without using any reaction indicators and detection equipments. We believe LAMP technology, with the integration of these features, can rightly apply to clinical genetic testing, food and environmental analysis, as well as NAT in different fields.

Improved nonlinear prediction method

NASA Astrophysics Data System (ADS)

Adenan, Nur Hamiza; Md Noorani, Mohd Salmi

2014-06-01

The analysis and prediction of time series data have been addressed by researchers. Many techniques have been developed to be applied in various areas, such as weather forecasting, financial markets and hydrological phenomena involving data that are contaminated by noise. Therefore, various techniques to improve the method have been introduced to analyze and predict time series data. In respect of the importance of analysis and the accuracy of the prediction result, a study was undertaken to test the effectiveness of the improved nonlinear prediction method for data that contain noise. The improved nonlinear prediction method involves the formation of composite serial data based on the successive differences of the time series. Then, the phase space reconstruction was performed on the composite data (one-dimensional) to reconstruct a number of space dimensions. Finally the local linear approximation method was employed to make a prediction based on the phase space. This improved method was tested with data series Logistics that contain 0%, 5%, 10%, 20% and 30% of noise. The results show that by using the improved method, the predictions were found to be in close agreement with the observed ones. The correlation coefficient was close to one when the improved method was applied on data with up to 10% noise. Thus, an improvement to analyze data with noise without involving any noise reduction method was introduced to predict the time series data.

Language Practitioners' Reflections on Method-Based and Post-Method Pedagogies

ERIC Educational Resources Information Center

Soomro, Abdul Fattah; Almalki, Mansoor S.

2017-01-01

Method-based pedagogies are commonly applied in teaching English as a foreign language all over the world. However, in the last quarter of the 20th century, the concept of such pedagogies based on the application of a single best method in EFL started to be viewed with concerns by some scholars. In response to the growing concern against the…

Overview On Alternative Asbestos Control Method Research: Alternative Methods To Demolition

EPA Science Inventory

The Alternative Asbestos Control Method (AACM) is an experimental approach to building demolition. Unlike the NESHAP method, the AACM allows some regulated asbestos-containing material to remain in the building and a surfactant-water solution is used to suppress asbestos fibers ...

Computational Methods in Drug Discovery

PubMed Central

Sliwoski, Gregory; Kothiwale, Sandeepkumar; Meiler, Jens

2014-01-01

Computer-aided drug discovery/design methods have played a major role in the development of therapeutically important small molecules for over three decades. These methods are broadly classified as either structure-based or ligand-based methods. Structure-based methods are in principle analogous to high-throughput screening in that both target and ligand structure information is imperative. Structure-based approaches include ligand docking, pharmacophore, and ligand design methods. The article discusses theory behind the most important methods and recent successful applications. Ligand-based methods use only ligand information for predicting activity depending on its similarity/dissimilarity to previously known active ligands. We review widely used ligand-based methods such as ligand-based pharmacophores, molecular descriptors, and quantitative structure-activity relationships. In addition, important tools such as target/ligand data bases, homology modeling, ligand fingerprint methods, etc., necessary for successful implementation of various computer-aided drug discovery/design methods in a drug discovery campaign are discussed. Finally, computational methods for toxicity prediction and optimization for favorable physiologic properties are discussed with successful examples from literature. PMID:24381236

Overview of paint removal methods

NASA Astrophysics Data System (ADS)

Foster, Terry

1995-04-01

With the introduction of strict environmental regulations governing the use and disposal of methylene chloride and phenols, major components of chemical paint strippers, there have been many new environmentally safe and effective methods of paint removal developed. The new methods developed for removing coatings from aircraft and aircraft components include: mechanical methods using abrasive media such as plastic, wheat starch, walnut shells, ice and dry ice, environmentally safe chemical strippers and paint softeners, and optical methods such as lasers and flash lamps. Each method has its advantages and disadvantages, and some have unique applications. For example, mechanical and abrasive methods can damage sensitive surfaces such as composite materials and strict control of blast parameters and conditions are required. Optical methods can be slow, leaving paint residues, and chemical methods may not remove all of the coating or require special coating formulations to be effective. As an introduction to environmentally safe and effective methods of paint removal, this paper is an overview of the various methods available. The purpose of this overview is to introduce the various paint removal methods available.

John Butcher and hybrid methods

NASA Astrophysics Data System (ADS)

Mehdiyeva, Galina; Imanova, Mehriban; Ibrahimov, Vagif

2017-07-01

As is known there are the mainly two classes of the numerical methods for solving ODE, which is commonly called a one and multistep methods. Each of these methods has certain advantages and disadvantages. It is obvious that the method which has better properties of these methods should be constructed at the junction of them. In the middle of the XX century, Butcher and Gear has constructed at the junction of the methods of Runge-Kutta and Adams, which is called hybrid method. Here considers the construction of certain generalizations of hybrid methods, with the high order of accuracy and to explore their application to solving the Ordinary Differential, Volterra Integral and Integro-Differential equations. Also have constructed some specific hybrid methods with the degree p ≤ 10.

The Base 32 Method: An Improved Method for Coding Sibling Constellations.

ERIC Educational Resources Information Center

Perfetti, Lawrence J. Carpenter

1990-01-01

Offers new sibling constellation coding method (Base 32) for genograms using binary and base 32 numbers that saves considerable microcomputer memory. Points out that new method will result in greater ability to store and analyze larger amounts of family data. (Author/CM)

Consensus methods: review of original methods and their main alternatives used in public health

PubMed Central

Bourrée, Fanny; Michel, Philippe; Salmi, Louis Rachid

2008-01-01

Summary Background Consensus-based studies are increasingly used as decision-making methods, for they have lower production cost than other methods (observation, experimentation, modelling) and provide results more rapidly. The objective of this paper is to describe the principles and methods of the four main methods, Delphi, nominal group, consensus development conference and RAND/UCLA, their use as it appears in peer-reviewed publications and validation studies published in the healthcare literature. Methods A bibliographic search was performed in Pubmed/MEDLINE, Banque de Données Santé Publique (BDSP), The Cochrane Library, Pascal and Francis. Keywords, headings and qualifiers corresponding to a list of terms and expressions related to the consensus methods were searched in the thesauri, and used in the literature search. A search with the same terms and expressions was performed on Internet using the website Google Scholar. Results All methods, precisely described in the literature, are based on common basic principles such as definition of subject, selection of experts, and direct or remote interaction processes. They sometimes use quantitative assessment for ranking items. Numerous variants of these methods have been described. Few validation studies have been implemented. Not implementing these basic principles and failing to describe the methods used to reach the consensus were both frequent reasons contributing to raise suspicion regarding the validity of consensus methods. Conclusion When it is applied to a new domain with important consequences in terms of decision making, a consensus method should be first validated. PMID:19013039

Space methods in oceanology

NASA Technical Reports Server (NTRS)

Bolshakov, A. A.

1985-01-01

The study of Earth from space with specialized satellites, and from manned orbiting stations, has become important in the space programs. The broad complex of methods used for probing Earth from space are different methods of the study of ocean, dynamics. The different methods of ocean observation are described.

Structural reliability calculation method based on the dual neural network and direct integration method.

PubMed

Li, Haibin; He, Yun; Nie, Xiaobo

2018-01-01

Structural reliability analysis under uncertainty is paid wide attention by engineers and scholars due to reflecting the structural characteristics and the bearing actual situation. The direct integration method, started from the definition of reliability theory, is easy to be understood, but there are still mathematics difficulties in the calculation of multiple integrals. Therefore, a dual neural network method is proposed for calculating multiple integrals in this paper. Dual neural network consists of two neural networks. The neural network A is used to learn the integrand function, and the neural network B is used to simulate the original function. According to the derivative relationships between the network output and the network input, the neural network B is derived from the neural network A. On this basis, the performance function of normalization is employed in the proposed method to overcome the difficulty of multiple integrations and to improve the accuracy for reliability calculations. The comparisons between the proposed method and Monte Carlo simulation method, Hasofer-Lind method, the mean value first-order second moment method have demonstrated that the proposed method is an efficient and accurate reliability method for structural reliability problems.

A Person-Oriented Approach: Methods for Today and Methods for Tomorrow

ERIC Educational Resources Information Center

Bergman, Lars R.; El-Khouri, Bassam M.

2003-01-01

Methodological implications of a person-oriented, holistic-interactionistic perspective in research on individual development are outlined, desirable properties of a mathematical model of a phenomenon are discussed, and selected methods for carrying out person-oriented research are briefly overviewed. These methods are: (1) the classificatory…

Method Development in Forensic Toxicology.

PubMed

Peters, Frank T; Wissenbach, Dirk K; Busardo, Francesco Paolo; Marchei, Emilia; Pichini, Simona

2017-01-01

In the field of forensic toxicology, the quality of analytical methods is of great importance to ensure the reliability of results and to avoid unjustified legal consequences. A key to high quality analytical methods is a thorough method development. The presented article will provide an overview on the process of developing methods for forensic applications. This includes the definition of the method's purpose (e.g. qualitative vs quantitative) and the analytes to be included, choosing an appropriate sample matrix, setting up separation and detection systems as well as establishing a versatile sample preparation. Method development is concluded by an optimization process after which the new method is subject to method validation. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

DISCOURSE ON METHODS.

ERIC Educational Resources Information Center

BOUCHER, JOHN G.

THE AUTHOR STATES THAT BEFORE PRESENT FOREIGN LANGUAGE TEACHING METHODS CAN BE DISCUSSED INTELLIGENTLY, THE RESEARCH IN PSYCHOLOGY AND LINGUISTICS WHICH HAS INFLUENCED THE DEVELOPMENT OF THESE METHODS MUST BE CONSIDERED. MANY FOREIGN LANGUAGE TEACHERS WERE BEGINNING TO FEEL COMFORTABLE WITH THE AUDIOLINGUAL APPROACH WHEN NOAM CHOMSKY, IN HIS 1966…

Water treatment method

DOEpatents

Martin, Frank S.; Silver, Gary L.

1991-04-30

A method for reducing the concentration of any undesirable metals dissolved in contaminated water, such as waste water. The method involves uniformly reacting the contaminated water with an excess amount of solid particulate calcium sulfite to insolubilize the undesirable metal ions, followed by removal thereof and of the unreacted calcium sulfite.

Validating Analytical Methods

ERIC Educational Resources Information Center

Ember, Lois R.

1977-01-01

The procedures utilized by the Association of Official Analytical Chemists (AOAC) to develop, evaluate, and validate analytical methods for the analysis of chemical pollutants are detailed. Methods validated by AOAC are used by the EPA and FDA in their enforcement programs and are granted preferential treatment by the courts. (BT)

Coherent Anomaly Method Calculation on the Cluster Variation Method. II.

NASA Astrophysics Data System (ADS)

Wada, Koh; Watanabe, Naotosi; Uchida, Tetsuya

The critical exponents of the bond percolation model are calculated in the D(= 2,3,…)-dimensional simple cubic lattice on the basis of Suzuki's coherent anomaly method (CAM) by making use of a series of the pair, the square-cactus and the square approximations of the cluster variation method (CVM) in the s-state Potts model. These simple approximations give reasonable values of critical exponents α, β, γ and ν in comparison with ones estimated by other methods. It is also shown that the results of the pair and the square-cactus approximations can be derived as exact results of the bond percolation model on the Bethe and the square-cactus lattice, respectively, in the presence of ghost field without recourse to the s→1 limit of the s-state Potts model.

John Herschel's Graphical Method

NASA Astrophysics Data System (ADS)

Hankins, Thomas L.

2011-01-01

In 1833 John Herschel published an account of his graphical method for determining the orbits of double stars. He had hoped to be the first to determine such orbits, but Felix Savary in France and Johann Franz Encke in Germany beat him to the punch using analytical methods. Herschel was convinced, however, that his graphical method was much superior to analytical methods, because it used the judgment of the hand and eye to correct the inevitable errors of observation. Line graphs of the kind used by Herschel became common only in the 1830s, so Herschel was introducing a new method. He also found computation fatiguing and devised a "wheeled machine" to help him out. Encke was skeptical of Herschel's methods. He said that he lived for calculation and that the English would be better astronomers if they calculated more. It is difficult to believe that the entire Scientific Revolution of the 17th century took place without graphs and that only a few examples appeared in the 18th century. Herschel promoted the use of graphs, not only in astronomy, but also in the study of meteorology and terrestrial magnetism. Because he was the most prominent scientist in England, Herschel's advocacy greatly advanced graphical methods.

Methods comparison for microsatellite marker development: Different isolation methods, different yield efficiency

NASA Astrophysics Data System (ADS)

Zhan, Aibin; Bao, Zhenmin; Hu, Xiaoli; Lu, Wei; Hu, Jingjie

2009-06-01

Microsatellite markers have become one kind of the most important molecular tools used in various researches. A large number of microsatellite markers are required for the whole genome survey in the fields of molecular ecology, quantitative genetics and genomics. Therefore, it is extremely necessary to select several versatile, low-cost, efficient and time- and labor-saving methods to develop a large panel of microsatellite markers. In this study, we used Zhikong scallop ( Chlamys farreri) as the target species to compare the efficiency of the five methods derived from three strategies for microsatellite marker development. The results showed that the strategy of constructing small insert genomic DNA library resulted in poor efficiency, while the microsatellite-enriched strategy highly improved the isolation efficiency. Although the mining public database strategy is time- and cost-saving, it is difficult to obtain a large number of microsatellite markers, mainly due to the limited sequence data of non-model species deposited in public databases. Based on the results in this study, we recommend two methods, microsatellite-enriched library construction method and FIASCO-colony hybridization method, for large-scale microsatellite marker development. Both methods were derived from the microsatellite-enriched strategy. The experimental results obtained from Zhikong scallop also provide the reference for microsatellite marker development in other species with large genomes.

Mixed methods in psychotherapy research: A review of method(ology) integration in psychotherapy science.

PubMed

Bartholomew, Theodore T; Lockard, Allison J

2018-06-13

Mixed methods can foster depth and breadth in psychological research. However, its use remains in development in psychotherapy research. Our purpose was to review the use of mixed methods in psychotherapy research. Thirty-one studies were identified via the PRISMA systematic review method. Using Creswell & Plano Clark's typologies to identify design characteristics, we assessed each study for rigor and how each used mixed methods. Key features of mixed methods designs and these common patterns were identified: (a) integration of clients' perceptions via mixing; (b) understanding group psychotherapy; (c) integrating methods with cases and small samples; (d) analyzing clinical data as qualitative data; and (e) exploring cultural identities in psychotherapy through mixed methods. The review is discussed with respect to the value of integrating multiple data in single studies to enhance psychotherapy research. © 2018 Wiley Periodicals, Inc.

Multi-resolution MPS method

NASA Astrophysics Data System (ADS)

Tanaka, Masayuki; Cardoso, Rui; Bahai, Hamid

2018-04-01

In this work, the Moving Particle Semi-implicit (MPS) method is enhanced for multi-resolution problems with different resolutions at different parts of the domain utilising a particle splitting algorithm for the finer resolution and a particle merging algorithm for the coarser resolution. The Least Square MPS (LSMPS) method is used for higher stability and accuracy. Novel boundary conditions are developed for the treatment of wall and pressure boundaries for the Multi-Resolution LSMPS method. A wall is represented by polygons for effective simulations of fluid flows with complex wall geometries and the pressure boundary condition allows arbitrary inflow and outflow, making the method easier to be used in flow simulations of channel flows. By conducting simulations of channel flows and free surface flows, the accuracy of the proposed method was verified.

Attribute-Based Methods

Treesearch

Thomas P. Holmes; Wiktor L. Adamowicz

2003-01-01

Stated preference methods of environmental valuation have been used by economists for decades where behavioral data have limitations. The contingent valuation method (Chapter 5) is the oldest stated preference approach, and hundreds of contingent valuation studies have been conducted. More recently, and especially over the last decade, a class of stated preference...

Water treatment method

DOEpatents

Martin, F.S.; Silver, G.L.

1991-04-30

A method is described for reducing the concentration of any undesirable metals dissolved in contaminated water, such as waste water. The method involves uniformly reacting the contaminated water with an excess amount of solid particulate calcium sulfite to insolubilize the undesirable metal ions, followed by removal thereof and of the unreacted calcium sulfite.

New Adsorption Methods.

ERIC Educational Resources Information Center

Wankat, Phillip C.

1984-01-01

Discusses a simple method for following the movement of a solute in an adsorption or ion exchange system. This movement is used to study a variety of operational methods, including continuous flow and pulsed flow counter-current operations and simulated counter-current systems. Effect of changing thermodynamic variables is also considered. (JM)

Spectral collocation methods

NASA Technical Reports Server (NTRS)

Hussaini, M. Y.; Kopriva, D. A.; Patera, A. T.

1987-01-01

This review covers the theory and application of spectral collocation methods. Section 1 describes the fundamentals, and summarizes results pertaining to spectral approximations of functions. Some stability and convergence results are presented for simple elliptic, parabolic, and hyperbolic equations. Applications of these methods to fluid dynamics problems are discussed in Section 2.

Toward cost-efficient sampling methods

NASA Astrophysics Data System (ADS)

Luo, Peng; Li, Yongli; Wu, Chong; Zhang, Guijie

2015-09-01

The sampling method has been paid much attention in the field of complex network in general and statistical physics in particular. This paper proposes two new sampling methods based on the idea that a small part of vertices with high node degree could possess the most structure information of a complex network. The two proposed sampling methods are efficient in sampling high degree nodes so that they would be useful even if the sampling rate is low, which means cost-efficient. The first new sampling method is developed on the basis of the widely used stratified random sampling (SRS) method and the second one improves the famous snowball sampling (SBS) method. In order to demonstrate the validity and accuracy of two new sampling methods, we compare them with the existing sampling methods in three commonly used simulation networks that are scale-free network, random network, small-world network, and also in two real networks. The experimental results illustrate that the two proposed sampling methods perform much better than the existing sampling methods in terms of achieving the true network structure characteristics reflected by clustering coefficient, Bonacich centrality and average path length, especially when the sampling rate is low.

Methods of forming semiconductor devices and devices formed using such methods

DOEpatents

Fox, Robert V; Rodriguez, Rene G; Pak, Joshua

2013-05-21

Single source precursors are subjected to carbon dioxide to form particles of material. The carbon dioxide may be in a supercritical state. Single source precursors also may be subjected to supercritical fluids other than supercritical carbon dioxide to form particles of material. The methods may be used to form nanoparticles. In some embodiments, the methods are used to form chalcopyrite materials. Devices such as, for example, semiconductor devices may be fabricated that include such particles. Methods of forming semiconductor devices include subjecting single source precursors to carbon dioxide to form particles of semiconductor material, and establishing electrical contact between the particles and an electrode.

Substituted 6-nitroquipazines, methods of preparation, and methods of use

DOEpatents

Mathis, Jr., Chester A.; Biegon, Anat; Taylor, Scott E.; Enas, Joel D.

1994-01-01

Disclosed is a substituted 6-nitroquipazine of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, and R.sub.4 are each selected from the group consisting of H, Fl, CL, Br, I, CF.sub.3, CH.sub.2 CH.sub.2 F, CH.sub.3, CH.sub.2 CH.sub.3, and --CH(CH.sub.3).sub.2, and wherein one of R.sub.1, R.sub.2, R.sub.3, and R.sub.4 is other than H. Also disclosed is a method for measurement of serotonin uptake sites in a sample, in which a radioligand is incubated with a sample and then the radioactivity of the radioligand bound to the sample is determined, utilizing a radio labeled substituted 6-nitroquipazine as the radioligand. Also disclosed is a method of manufacture and method of use.

Prospective Mathematics Teachers' Opinions about Mathematical Modeling Method and Applicability of This Method

ERIC Educational Resources Information Center

Akgün, Levent

2015-01-01

The aim of this study is to identify prospective secondary mathematics teachers' opinions about the mathematical modeling method and the applicability of this method in high schools. The case study design, which is among the qualitative research methods, was used in the study. The study was conducted with six prospective secondary mathematics…

[Comparative clinical analysis of cesarean section technique by Misgav Ladach method and Pfennenstiel method].

PubMed

Popiela, A; Pańszczyk, M; Korzeniewski, J; Baranowski, W

2000-04-01

Clinical and biochemical parameters were analysed in 55 patients who underwent a caesarean section performed using Misgav Ladach method compared to reference group of 41 patients who underwent caesarean section using Pfannenstiel method. Shortened operation time, shortened hospitalisation time and less postoperative morbidity were observed in the Misgav Ladach group. This kind of method seems to have advantages in comparison to Pfannenstiel method.

Vector potential methods

NASA Technical Reports Server (NTRS)

Hafez, M.

1989-01-01

Vector potential and related methods, for the simulation of both inviscid and viscous flows over aerodynamic configurations, are briefly reviewed. The advantages and disadvantages of several formulations are discussed and alternate strategies are recommended. Scalar potential, modified potential, alternate formulations of Euler equations, least-squares formulation, variational principles, iterative techniques and related methods, and viscous flow simulation are discussed.

Water-budget methods

USGS Publications Warehouse

Healy, Richard W.; Scanlon, Bridget R.

2010-01-01

A water budget is an accounting of water movement into and out of, and storage change within, some control volume. Universal and adaptable are adjectives that reflect key features of water-budget methods for estimating recharge. The universal concept of mass conservation of water implies that water-budget methods are applicable over any space and time scales (Healy et al., 2007). The water budget of a soil column in a laboratory can be studied at scales of millimeters and seconds. A water-budget equation is also an integral component of atmospheric general circulation models used to predict global climates over periods of decades or more. Water-budget equations can be easily customized by adding or removing terms to accurately portray the peculiarities of any hydrologic system. The equations are generally not bound by assumptions on mechanisms by which water moves into, through, and out of the control volume of interest. So water-budget methods can be used to estimate both diffuse and focused recharge, and recharge estimates are unaffected by phenomena such as preferential flow paths within the unsaturated zone.Water-budget methods represent the largest class of techniques for estimating recharge. Most hydrologic models are derived from a water-budget equation and can therefore be classified as water-budget models. It is not feasible to address all water-budget methods in a single chapter. This chapter is limited to discussion of the “residual” water-budget approach, whereby all variables in a water-budget equation, except for recharge, are independently measured or estimated and recharge is set equal to the residual. This chapter is closely linked with Chapter 3, on modeling methods, because the equations presented here form the basis of many models and because models are often used to estimate individual components in water-budget studies. Water budgets for streams and other surface-water bodies are addressed in Chapter 4. The use of soil-water budgets and

Geobacteraceae strains and methods

DOEpatents

Lovley, Derek R.; Nevin, Kelly P.; Yi, Hana

2015-07-07

Embodiments of the present invention provide a method of producing genetically modified strains of electricigenic microbes that are specifically adapted for the production of electrical current in microbial fuel cells, as well as strains produced by such methods and fuel cells using such strains. In preferred embodiments, the present invention provides genetically modified strains of Geobacter sulfurreducens and methods of using such strains.

Winograd Method Versus Winograd Method With Electrocoagulation in the Treatment of Ingrown Toenails.

PubMed

Acar, Erdinc

An important component of the Winograd surgical method for an ingrown toenail is total excision of the associated germinal matrix. However, this might not always be accomplished with the procedure. We hypothesized that the surgical results might be improved by adding electrocoagulation of the germinal matrix to the Winograd method. The objective of the present study was to compare the recurrence, satisfaction, and complication rates of the Winograd method with those of the Winograd method with electrocoagulation. We retrospectively evaluated the records of 102 patients with single Heifetz stage 2 or 3 ingrown toenails who had undergone surgery from January 2013 to October 2014 using 1 of these 2 methods. Of the 102 patients, 50 (49%) underwent the Winograd method and 52 (51%) underwent the Winograd method with electrocoagulation. The mean follow-up period of our patients was 12 (range 6 to 22) months. An ingrown toenail recurred in 3 patients (6%) in the Winograd group and in no patient in the Winograd with electrocoagulation group (p = .04). Among the patients in the Winograd group, 46 (92.0%) were satisfied or very satisfied. Among the patients in the Winograd plus electrocoagulation group, 49 (94.2%) were satisfied or very satisfied (p = .04). No complications developed in either group. In conclusion, the Winograd method for ingrown toenails results in high satisfaction rates, low recurrence rates, and low complication rates. The addition of electrocoagulation of the germinal matrix to the Winograd method could result in even lower recurrence rates, while maintaining high patient satisfaction and without increasing the risk of complications. Copyright © 2017 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.

Discontinuous Finite Element Quasidiffusion Methods

DOE PAGES

Anistratov, Dmitriy Yurievich; Warsa, James S.

2018-05-21

Here in this paper, two-level methods for solving transport problems in one-dimensional slab geometry based on the quasi-diffusion (QD) method are developed. A linear discontinuous finite element method (LDFEM) is derived for the spatial discretization of the low-order QD (LOQD) equations. It involves special interface conditions at the cell edges based on the idea of QD boundary conditions (BCs). We consider different kinds of QD BCs to formulate the necessary cell-interface conditions. We develop two-level methods with independent discretization of the high-order transport equation and LOQD equations, where the transport equation is discretized using the method of characteristics and themore » LDFEM is applied to the LOQD equations. We also formulate closures that lead to the discretization consistent with a LDFEM discretization of the transport equation. The proposed methods are studied by means of test problems formulated with the method of manufactured solutions. Numerical experiments are presented demonstrating the performance of the proposed methods. Lastly, we also show that the method with independent discretization has the asymptotic diffusion limit.« less

Discontinuous Finite Element Quasidiffusion Methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anistratov, Dmitriy Yurievich; Warsa, James S.

Here in this paper, two-level methods for solving transport problems in one-dimensional slab geometry based on the quasi-diffusion (QD) method are developed. A linear discontinuous finite element method (LDFEM) is derived for the spatial discretization of the low-order QD (LOQD) equations. It involves special interface conditions at the cell edges based on the idea of QD boundary conditions (BCs). We consider different kinds of QD BCs to formulate the necessary cell-interface conditions. We develop two-level methods with independent discretization of the high-order transport equation and LOQD equations, where the transport equation is discretized using the method of characteristics and themore » LDFEM is applied to the LOQD equations. We also formulate closures that lead to the discretization consistent with a LDFEM discretization of the transport equation. The proposed methods are studied by means of test problems formulated with the method of manufactured solutions. Numerical experiments are presented demonstrating the performance of the proposed methods. Lastly, we also show that the method with independent discretization has the asymptotic diffusion limit.« less

Impact of Uniform Methods on Interlaboratory Antibody Titration Variability: Antibody Titration and Uniform Methods.

PubMed

Bachegowda, Lohith S; Cheng, Yan H; Long, Thomas; Shaz, Beth H

2017-01-01

-Substantial variability between different antibody titration methods prompted development and introduction of uniform methods in 2008. -To determine whether uniform methods consistently decrease interlaboratory variation in proficiency testing. -Proficiency testing data for antibody titration between 2009 and 2013 were obtained from the College of American Pathologists. Each laboratory was supplied plasma and red cells to determine anti-A and anti-D antibody titers by their standard method: gel or tube by uniform or other methods at different testing phases (immediate spin and/or room temperature [anti-A], and/or anti-human globulin [AHG: anti-A and anti-D]) with different additives. Interlaboratory variations were compared by analyzing the distribution of titer results by method and phase. -A median of 574 and 1100 responses were reported for anti-A and anti-D antibody titers, respectively, during a 5-year period. The 3 most frequent (median) methods performed for anti-A antibody were uniform tube room temperature (147.5; range, 119-159), uniform tube AHG (143.5; range, 134-150), and other tube AHG (97; range, 82-116); for anti-D antibody, the methods were other tube (451; range, 431-465), uniform tube (404; range, 382-462), and uniform gel (137; range, 121-153). Of the larger reported methods, uniform gel AHG phase for anti-A and anti-D antibodies had the most participants with the same result (mode). For anti-A antibody, 0 of 8 (uniform versus other tube room temperature) and 1 of 8 (uniform versus other tube AHG), and for anti-D antibody, 0 of 8 (uniform versus other tube) and 0 of 8 (uniform versus other gel) proficiency tests showed significant titer variability reduction. -Uniform methods harmonize laboratory techniques but rarely reduce interlaboratory titer variance in comparison with other methods.

Probabilistic boundary element method

NASA Technical Reports Server (NTRS)

Cruse, T. A.; Raveendra, S. T.

1989-01-01

The purpose of the Probabilistic Structural Analysis Method (PSAM) project is to develop structural analysis capabilities for the design analysis of advanced space propulsion system hardware. The boundary element method (BEM) is used as the basis of the Probabilistic Advanced Analysis Methods (PADAM) which is discussed. The probabilistic BEM code (PBEM) is used to obtain the structural response and sensitivity results to a set of random variables. As such, PBEM performs analogous to other structural analysis codes such as finite elements in the PSAM system. For linear problems, unlike the finite element method (FEM), the BEM governing equations are written at the boundary of the body only, thus, the method eliminates the need to model the volume of the body. However, for general body force problems, a direct condensation of the governing equations to the boundary of the body is not possible and therefore volume modeling is generally required.

The Schwinger Variational Method

NASA Technical Reports Server (NTRS)

Huo, Winifred M.

1995-01-01

Variational methods have proven invaluable in theoretical physics and chemistry, both for bound state problems and for the study of collision phenomena. The application of the Schwinger variational (SV) method to e-molecule collisions and molecular photoionization has been reviewed previously. The present chapter discusses the implementation of the SV method as applied to e-molecule collisions. Since this is not a review of cross section data, cross sections are presented only to server as illustrative examples. In the SV method, the correct boundary condition is automatically incorporated through the use of Green's function. Thus SV calculations can employ basis functions with arbitrary boundary conditions. The iterative Schwinger method has been used extensively to study molecular photoionization. For e-molecule collisions, it is used at the static exchange level to study elastic scattering and coupled with the distorted wave approximation to study electronically inelastic scattering.

[Methods of quantitative proteomics].

PubMed

Kopylov, A T; Zgoda, V G

2007-01-01

In modern science proteomic analysis is inseparable from other fields of systemic biology. Possessing huge resources quantitative proteomics operates colossal information on molecular mechanisms of life. Advances in proteomics help researchers to solve complex problems of cell signaling, posttranslational modification, structure and functional homology of proteins, molecular diagnostics etc. More than 40 various methods have been developed in proteomics for quantitative analysis of proteins. Although each method is unique and has certain advantages and disadvantages all these use various isotope labels (tags). In this review we will consider the most popular and effective methods employing both chemical modifications of proteins and also metabolic and enzymatic methods of isotope labeling.

The multigrid preconditioned conjugate gradient method

NASA Technical Reports Server (NTRS)

Tatebe, Osamu

1993-01-01

A multigrid preconditioned conjugate gradient method (MGCG method), which uses the multigrid method as a preconditioner of the PCG method, is proposed. The multigrid method has inherent high parallelism and improves convergence of long wavelength components, which is important in iterative methods. By using this method as a preconditioner of the PCG method, an efficient method with high parallelism and fast convergence is obtained. First, it is considered a necessary condition of the multigrid preconditioner in order to satisfy requirements of a preconditioner of the PCG method. Next numerical experiments show a behavior of the MGCG method and that the MGCG method is superior to both the ICCG method and the multigrid method in point of fast convergence and high parallelism. This fast convergence is understood in terms of the eigenvalue analysis of the preconditioned matrix. From this observation of the multigrid preconditioner, it is realized that the MGCG method converges in very few iterations and the multigrid preconditioner is a desirable preconditioner of the conjugate gradient method.

[Physical methods and molecular biology].

PubMed

Serdiuk, I N

2009-01-01

The review is devoted to the description of the current state of physical and chemical methods used for studying the structural and functional bases of living processes. Special attention is focused on the physical methods that have opened a new page in the research of the structure of biological macromolecules. They include primarily the methods of detecting and manipulating single molecules using optical and magnetic traps. New physical methods, such as two-dimensional infrared spectroscopy, fluorescence correlation spectroscopy and magnetic resonance microscopy are also analyzed briefly in the review. The path that physics and biology have passed for the latest 55 years shows that there is no single method providing all necessary information on macromolecules and their interactions. Each method provides its space-time view of the system. All physical methods are complementary. It is just complementarity that is the fundamental idea justifying the existence in practice of all physical methods, whose description is the aim of the review.

Methods of refining natural oils, and methods of producing fuel compositions

DOEpatents

Firth, Bruce E.; Kirk, Sharon E.

2015-10-27

A method of refining a natural oil includes: (a) providing a feedstock that includes a natural oil; (b) reacting the feedstock in the presence of a metathesis catalyst to form a metathesized product that includes olefins and esters; (c) passivating residual metathesis catalyst with an agent that comprises nitric acid; (d) separating the olefins in the metathesized product from the esters in the metathesized product; and (e) transesterifying the esters in the presence of an alcohol to form a transesterified product and/or hydrogenating the olefins to form a fully or partially saturated hydrogenated product. Methods for suppressing isomerization of olefin metathesis products produced in a metathesis reaction, and methods of producing fuel compositions are described.

Efficient searching in meshfree methods

NASA Astrophysics Data System (ADS)

Olliff, James; Alford, Brad; Simkins, Daniel C.

2018-04-01

Meshfree methods such as the Reproducing Kernel Particle Method and the Element Free Galerkin method have proven to be excellent choices for problems involving complex geometry, evolving topology, and large deformation, owing to their ability to model the problem domain without the constraints imposed on the Finite Element Method (FEM) meshes. However, meshfree methods have an added computational cost over FEM that come from at least two sources: increased cost of shape function evaluation and the determination of adjacency or connectivity. The focus of this paper is to formally address the types of adjacency information that arises in various uses of meshfree methods; a discussion of available techniques for computing the various adjacency graphs; propose a new search algorithm and data structure; and finally compare the memory and run time performance of the methods.

Basics of Bayesian methods.

PubMed

Ghosh, Sujit K

2010-01-01

Bayesian methods are rapidly becoming popular tools for making statistical inference in various fields of science including biology, engineering, finance, and genetics. One of the key aspects of Bayesian inferential method is its logical foundation that provides a coherent framework to utilize not only empirical but also scientific information available to a researcher. Prior knowledge arising from scientific background, expert judgment, or previously collected data is used to build a prior distribution which is then combined with current data via the likelihood function to characterize the current state of knowledge using the so-called posterior distribution. Bayesian methods allow the use of models of complex physical phenomena that were previously too difficult to estimate (e.g., using asymptotic approximations). Bayesian methods offer a means of more fully understanding issues that are central to many practical problems by allowing researchers to build integrated models based on hierarchical conditional distributions that can be estimated even with limited amounts of data. Furthermore, advances in numerical integration methods, particularly those based on Monte Carlo methods, have made it possible to compute the optimal Bayes estimators. However, there is a reasonably wide gap between the background of the empirically trained scientists and the full weight of Bayesian statistical inference. Hence, one of the goals of this chapter is to bridge the gap by offering elementary to advanced concepts that emphasize linkages between standard approaches and full probability modeling via Bayesian methods.

Leaf Histology--Two Modern Methods.

ERIC Educational Resources Information Center

Freeman, H. E.

1984-01-01

Two methods for examining leaf structure are presented; both methods involve use of "superglue." The first method uses the glue to form a thin, permanent, direct replica of a leaf surface on a microscope slide. The second method uses the glue to examine the three-dimensional structure of spongy mesophyll. (JN)

The lod score method.

PubMed

Rice, J P; Saccone, N L; Corbett, J

2001-01-01

The lod score method originated in a seminal article by Newton Morton in 1955. The method is broadly concerned with issues of power and the posterior probability of linkage, ensuring that a reported linkage has a high probability of being a true linkage. In addition, the method is sequential, so that pedigrees or lod curves may be combined from published reports to pool data for analysis. This approach has been remarkably successful for 50 years in identifying disease genes for Mendelian disorders. After discussing these issues, we consider the situation for complex disorders, where the maximum lod score (MLS) statistic shares some of the advantages of the traditional lod score approach but is limited by unknown power and the lack of sharing of the primary data needed to optimally combine analytic results. We may still learn from the lod score method as we explore new methods in molecular biology and genetic analysis to utilize the complete human DNA sequence and the cataloging of all human genes.

Semi-supervised clustering methods.

PubMed

Bair, Eric

2013-01-01

Cluster analysis methods seek to partition a data set into homogeneous subgroups. It is useful in a wide variety of applications, including document processing and modern genetics. Conventional clustering methods are unsupervised, meaning that there is no outcome variable nor is anything known about the relationship between the observations in the data set. In many situations, however, information about the clusters is available in addition to the values of the features. For example, the cluster labels of some observations may be known, or certain observations may be known to belong to the same cluster. In other cases, one may wish to identify clusters that are associated with a particular outcome variable. This review describes several clustering algorithms (known as "semi-supervised clustering" methods) that can be applied in these situations. The majority of these methods are modifications of the popular k-means clustering method, and several of them will be described in detail. A brief description of some other semi-supervised clustering algorithms is also provided.

Spectral methods for CFD

NASA Technical Reports Server (NTRS)

Zang, Thomas A.; Streett, Craig L.; Hussaini, M. Yousuff

1989-01-01

One of the objectives of these notes is to provide a basic introduction to spectral methods with a particular emphasis on applications to computational fluid dynamics. Another objective is to summarize some of the most important developments in spectral methods in the last two years. The fundamentals of spectral methods for simple problems will be covered in depth, and the essential elements of several fluid dynamical applications will be sketched.

77 FR 48733 - Transitional Program for Covered Business Method Patents-Definitions of Covered Business Method...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-14

... Office 37 CFR Part 42 Transitional Program for Covered Business Method Patents--Definitions of Covered Business Method Patent and Technological Invention; Final Rule #0;#0;Federal Register / Vol. 77 , No. 157... Business Method Patents-- Definitions of Covered Business Method Patent and Technological Invention AGENCY...

Interlaboratory Validation of the Leaching Environmental Assessment Framework (LEAF) Method 1313 and Method 1316

EPA Science Inventory

This document summarizes the results of an interlaboratory study conducted to generate precision estimates for two parallel batch leaching methods which are part of the Leaching Environmental Assessment Framework (LEAF). These methods are: (1) Method 1313: Liquid-Solid Partition...

Optimal back-extrapolation method for estimating plasma volume in humans using the indocyanine green dilution method

PubMed Central

2014-01-01

Background The indocyanine green dilution method is one of the methods available to estimate plasma volume, although some researchers have questioned the accuracy of this method. Methods We developed a new, physiologically based mathematical model of indocyanine green kinetics that more accurately represents indocyanine green kinetics during the first few minutes postinjection than what is assumed when using the traditional mono-exponential back-extrapolation method. The mathematical model is used to develop an optimal back-extrapolation method for estimating plasma volume based on simulated indocyanine green kinetics obtained from the physiological model. Results Results from a clinical study using the indocyanine green dilution method in 36 subjects with type 2 diabetes indicate that the estimated plasma volumes are considerably lower when using the traditional back-extrapolation method than when using the proposed back-extrapolation method (mean (standard deviation) plasma volume = 26.8 (5.4) mL/kg for the traditional method vs 35.1 (7.0) mL/kg for the proposed method). The results obtained using the proposed method are more consistent with previously reported plasma volume values. Conclusions Based on the more physiological representation of indocyanine green kinetics and greater consistency with previously reported plasma volume values, the new back-extrapolation method is proposed for use when estimating plasma volume using the indocyanine green dilution method. PMID:25052018

PARTIAL RESTRAINING FORCE INTRODUCTION METHOD FOR DESIGNING CONSTRUCTION COUNTERMESURE ON ΔB METHOD

NASA Astrophysics Data System (ADS)

Nishiyama, Taku; Imanishi, Hajime; Chiba, Noriyuki; Ito, Takao

Landslide or slope failure is a three-dimensional movement phenomenon, thus a three-dimensional treatment makes it easier to understand stability. The ΔB method (simplified three-dimensional slope stability analysis method) is based on the limit equilibrium method and equals to an approximate three-dimensional slope stability analysis that extends two-dimensional cross-section stability analysis results to assess stability. This analysis can be conducted using conventional spreadsheets or two-dimensional slope stability computational software. This paper describes the concept of the partial restraining force in-troduction method for designing construction countermeasures using the distribution of the restraining force found along survey lines, which is based on the distribution of survey line safety factors derived from the above-stated analysis. This paper also presents the transverse distributive method of restraining force used for planning ground stabilizing on the basis of the example analysis.

Optimal back-extrapolation method for estimating plasma volume in humans using the indocyanine green dilution method.

PubMed

Polidori, David; Rowley, Clarence

2014-07-22

The indocyanine green dilution method is one of the methods available to estimate plasma volume, although some researchers have questioned the accuracy of this method. We developed a new, physiologically based mathematical model of indocyanine green kinetics that more accurately represents indocyanine green kinetics during the first few minutes postinjection than what is assumed when using the traditional mono-exponential back-extrapolation method. The mathematical model is used to develop an optimal back-extrapolation method for estimating plasma volume based on simulated indocyanine green kinetics obtained from the physiological model. Results from a clinical study using the indocyanine green dilution method in 36 subjects with type 2 diabetes indicate that the estimated plasma volumes are considerably lower when using the traditional back-extrapolation method than when using the proposed back-extrapolation method (mean (standard deviation) plasma volume = 26.8 (5.4) mL/kg for the traditional method vs 35.1 (7.0) mL/kg for the proposed method). The results obtained using the proposed method are more consistent with previously reported plasma volume values. Based on the more physiological representation of indocyanine green kinetics and greater consistency with previously reported plasma volume values, the new back-extrapolation method is proposed for use when estimating plasma volume using the indocyanine green dilution method.

[Comparative analysis between diatom nitric acid digestion method and plankton 16S rDNA PCR method].

PubMed

Han, Jun-ge; Wang, Cheng-bao; Li, Xing-biao; Fan, Yan-yan; Feng, Xiang-ping

2013-10-01

To compare and explore the application value of diatom nitric acid digestion method and plankton 16S rDNA PCR method for drowning identification. Forty drowning cases from 2010 to 2011 were collected from Department of Forensic Medicine of Wenzhou Medical University. Samples including lung, kidney, liver and field water from each case were tested with diatom nitric acid digestion method and plankton 16S rDNA PCR method, respectively. The Diatom nitric acid digestion method and plankton 16S rDNA PCR method required 20 g and 2 g of each organ, and 15 mL and 1.5 mL of field water, respectively. The inspection time and detection rate were compared between the two methods. Diatom nitric acid digestion method mainly detected two species of diatoms, Centriae and Pennatae, while plankton 16S rDNA PCR method amplified a length of 162 bp band. The average inspection time of each case of the Diatom nitric acid digestion method was (95.30 +/- 2.78) min less than (325.33 +/- 14.18) min of plankton 16S rDNA PCR method (P < 0.05). The detection rates of two methods for field water and lung were both 100%. For liver and kidney, the detection rate of plankton 16S rDNA PCR method was both 80%, higher than 40% and 30% of diatom nitric acid digestion method (P < 0.05), respectively. The laboratory testing method needs to be appropriately selected according to the specific circumstances in the forensic appraisal of drowning. Compared with diatom nitric acid digestion method, plankton 16S rDNA PCR method has practice values with such advantages as less quantity of samples, huge information and high specificity.

Exponentially fitted symplectic Runge-Kutta-Nyström methods derived by partitioned Runge-Kutta methods

NASA Astrophysics Data System (ADS)

Monovasilis, Th.; Kalogiratou, Z.; Simos, T. E.

2013-10-01

In this work we derive symplectic EF/TF RKN methods by symplectic EF/TF PRK methods. Also EF/TF symplectic RKN methods are constructed directly from classical symplectic RKN methods. Several numerical examples will be given in order to decide which is the most favourable implementation.

[Comparison of the quick Gram stain method to the B&M modified and favor methods].

PubMed

Osawa, Kayo; Kataoka, Nobumasa; Maruo, Toshio

2011-01-01

The Gram stain is an established method for bacterial identification, but the time needed to carry out this stain is 2-3 min. We attempted to shorten this time and stained a total of 70 clinical specimens isolated from using the Bartholomew & Mittwer (B&M) modified or Favor methods with a 3 s duration for washing and staining steps. Results were plotted and analyzed using a Hue Saturation Intensity (HSI) model. The range based on a plot of the two methods with the HSI model was presented as a reference interval. Our results indicated that 100% (35/35) of strains were Gram positive and 97.1% (34/35) were Gram negative for the quick B&M modified method. In the quick Favor method, 80.0% (28/35) were Gram positive and 68.6% (24/35) of strains were Gram negative. We propose that the quick B&M modified method is equivalent to the standard Gram staining method and is superior to the quick Favor method.

Machine learning methods can replace 3D profile method in classification of amyloidogenic hexapeptides.

PubMed

Stanislawski, Jerzy; Kotulska, Malgorzata; Unold, Olgierd

2013-01-17

Amyloids are proteins capable of forming fibrils. Many of them underlie serious diseases, like Alzheimer disease. The number of amyloid-associated diseases is constantly increasing. Recent studies indicate that amyloidogenic properties can be associated with short segments of aminoacids, which transform the structure when exposed. A few hundreds of such peptides have been experimentally found. Experimental testing of all possible aminoacid combinations is currently not feasible. Instead, they can be predicted by computational methods. 3D profile is a physicochemical-based method that has generated the most numerous dataset - ZipperDB. However, it is computationally very demanding. Here, we show that dataset generation can be accelerated. Two methods to increase the classification efficiency of amyloidogenic candidates are presented and tested: simplified 3D profile generation and machine learning methods. We generated a new dataset of hexapeptides, using more economical 3D profile algorithm, which showed very good classification overlap with ZipperDB (93.5%). The new part of our dataset contains 1779 segments, with 204 classified as amyloidogenic. The dataset of 6-residue sequences with their binary classification, based on the energy of the segment, was applied for training machine learning methods. A separate set of sequences from ZipperDB was used as a test set. The most effective methods were Alternating Decision Tree and Multilayer Perceptron. Both methods obtained area under ROC curve of 0.96, accuracy 91%, true positive rate ca. 78%, and true negative rate 95%. A few other machine learning methods also achieved a good performance. The computational time was reduced from 18-20 CPU-hours (full 3D profile) to 0.5 CPU-hours (simplified 3D profile) to seconds (machine learning). We showed that the simplified profile generation method does not introduce an error with regard to the original method, while increasing the computational efficiency. Our new dataset

Methods of refining natural oils and methods of producing fuel compositions

DOEpatents

Firth, Bruce E; Kirk, Sharon E; Gavaskar, Vasudeo S

2015-11-04

A method of refining a natural oil includes: (a) providing a feedstock that includes a natural oil; (b) reacting the feedstock in the presence of a metathesis catalyst to form a metathesized product that includes olefins and esters; (c) passivating residual metathesis catalyst with an agent selected from the group consisting of phosphorous acid, phosphinic acid, and a combination thereof; (d) separating the olefins in the metathesized product from the esters in the metathesized product; and (e) transesterifying the esters in the presence of an alcohol to form a transesterified product and/or hydrogenating the olefins to form a fully or partially saturated hydrogenated product. Methods for suppressing isomerization of olefin metathesis products produced in a metathesis reaction, and methods of producing fuel compositions are described.

"Phenomenology" and qualitative research methods.

PubMed

Nakayama, Y

1994-01-01

Phenomenology is generally based on phenomenological tradition from Husserl to Heidegger and Merleau-Ponty. As philosophical stances provide the assumptions in research methods, different philosophical stances produce different methods. However, the term "phenomenology" is used in various ways without the definition being given, such as phenomenological approach, phenomenological method, phenomenological research, etc. The term "phenomenology" is sometimes used as a paradigm and it is sometimes even viewed as synonymous with qualitative methods. As a result, the term "phenomenology" leads to conceptual confusions in qualitative research methods. The purpose of this paper is to examine the term "phenomenology" and explore philosophical assumptions, and discuss the relationship between philosophical stance and phenomenology as a qualitative research method in nursing.

Method Engineering: A Service-Oriented Approach

NASA Astrophysics Data System (ADS)

Cauvet, Corine

In the past, a large variety of methods have been published ranging from very generic frameworks to methods for specific information systems. Method Engineering has emerged as a research discipline for designing, constructing and adapting methods for Information Systems development. Several approaches have been proposed as paradigms in method engineering. The meta modeling approach provides means for building methods by instantiation, the component-based approach aims at supporting the development of methods by using modularization constructs such as method fragments, method chunks and method components. This chapter presents an approach (SO2M) for method engineering based on the service paradigm. We consider services as autonomous computational entities that are self-describing, self-configuring and self-adapting. They can be described, published, discovered and dynamically composed for processing a consumer's demand (a developer's requirement). The method service concept is proposed to capture a development process fragment for achieving a goal. Goal orientation in service specification and the principle of service dynamic composition support method construction and method adaptation to different development contexts.

Factorization method of quadratic template

NASA Astrophysics Data System (ADS)

Kotyrba, Martin

2017-07-01

Multiplication of two numbers is a one-way function in mathematics. Any attempt to distribute the outcome to its roots is called factorization. There are many methods such as Fermat's factorization, Dixońs method or quadratic sieve and GNFS, which use sophisticated techniques fast factorization. All the above methods use the same basic formula differing only in its use. This article discusses a newly designed factorization method. Effective implementation of this method in programs is not important, it only represents and clearly defines its properties.

Fitting methods to paradigms: are ergonomics methods fit for systems thinking?

PubMed

Salmon, Paul M; Walker, Guy H; M Read, Gemma J; Goode, Natassia; Stanton, Neville A

2017-02-01

The issues being tackled within ergonomics problem spaces are shifting. Although existing paradigms appear relevant for modern day systems, it is worth questioning whether our methods are. This paper asks whether the complexities of systems thinking, a currently ubiquitous ergonomics paradigm, are outpacing the capabilities of our methodological toolkit. This is achieved through examining the contemporary ergonomics problem space and the extent to which ergonomics methods can meet the challenges posed. Specifically, five key areas within the ergonomics paradigm of systems thinking are focused on: normal performance as a cause of accidents, accident prediction, system migration, systems concepts and ergonomics in design. The methods available for pursuing each line of inquiry are discussed, along with their ability to respond to key requirements. In doing so, a series of new methodological requirements and capabilities are identified. It is argued that further methodological development is required to provide researchers and practitioners with appropriate tools to explore both contemporary and future problems. Practitioner Summary: Ergonomics methods are the cornerstone of our discipline. This paper examines whether our current methodological toolkit is fit for purpose given the changing nature of ergonomics problems. The findings provide key research and practice requirements for methodological development.

Integration of gas chromatography mass spectrometry methods for differentiating ricin preparation methods.

PubMed

Wunschel, David S; Melville, Angela M; Ehrhardt, Christopher J; Colburn, Heather A; Victry, Kristin D; Antolick, Kathryn C; Wahl, Jon H; Wahl, Karen L

2012-05-07

The investigation of crimes involving chemical or biological agents is infrequent, but presents unique analytical challenges. The protein toxin ricin is encountered more frequently than other agents and is found in the seeds of Ricinus communis, commonly known as the castor plant. Typically, the toxin is extracted from castor seeds utilizing a variety of different recipes that result in varying purity of the toxin. Moreover, these various purification steps can also leave or differentially remove a variety of exogenous and endogenous residual components with the toxin that may indicate the type and number of purification steps involved. We have applied three gas chromatography-mass spectrometry (GC-MS) based analytical methods to measure the variation in seed carbohydrates and castor oil ricinoleic acid, as well as the presence of solvents used for purification. These methods were applied to the same samples prepared using four previously identified toxin preparation methods, starting from four varieties of castor seeds. The individual data sets for seed carbohydrate profiles, ricinoleic acid, or acetone amount each provided information capable of differentiating different types of toxin preparations across seed types. However, the integration of the data sets using multivariate factor analysis provided a clear distinction of all samples based on the preparation method, independent of the seed source. In particular, the abundance of mannose, arabinose, fucose, ricinoleic acid, and acetone were shown to be important differentiating factors. These complementary tools provide a more confident determination of the method of toxin preparation than would be possible using a single analytical method.

MULTIPOLLUTANT METHODS - METHODS FOR OZONE AND OZONE PRECURSORS

EPA Science Inventory

This task involves the development and testing of methods for monitoring ozone and compounds associated with the atmospheric chemistry of ozone production both as precursors and reaction products. Although atmospheric gases are the primary interest, separation of gas and particl...

Methods for chromosome-specific staining

DOEpatents

Gray, Joe W.; Pinkel, Daniel

1995-01-01

Methods and compositions for chromosome-specific staining are provided. Compositions comprise heterogenous mixtures of labeled nucleic acid fragments having substantially complementary base sequences to unique sequence regions of the chromosomal DNA for which their associated staining reagent is specific. Methods include methods for making the chromosome-specific staining compositions of the invention, and methods for applying the staining compositions to chromosomes.

Withdrawal Method (Coitus Interruptus)

MedlinePlus

Withdrawal method (coitus interruptus) Overview The withdrawal method of contraception, also known as coitus interruptus, is the practice of withdrawing the penis from the vagina and away from a woman's external ...

SAM Pathogen Methods Query

EPA Pesticide Factsheets

Laboratories measuring target pathogen analytes in environmental samples can use this online query tool to identify analytical methods in EPA's Selected Analytical Methods for Environmental Remediation and Recovery for select pathogens.

Aircraft digital control design methods

NASA Technical Reports Server (NTRS)

Powell, J. D.; Parsons, E.; Tashker, M. G.

1976-01-01

Variations in design methods for aircraft digital flight control are evaluated and compared. The methods fall into two categories; those where the design is done in the continuous domain (or s plane) and those where the design is done in the discrete domain (or z plane). Design method fidelity is evaluated by examining closed loop root movement and the frequency response of the discretely controlled continuous aircraft. It was found that all methods provided acceptable performance for sample rates greater than 10 cps except the uncompensated s plane design method which was acceptable above 20 cps. A design procedure based on optimal control methods was proposed that provided the best fidelity at very slow sample rates and required no design iterations for changing sample rates.

Semi-supervised clustering methods

PubMed Central

Bair, Eric

2013-01-01

Cluster analysis methods seek to partition a data set into homogeneous subgroups. It is useful in a wide variety of applications, including document processing and modern genetics. Conventional clustering methods are unsupervised, meaning that there is no outcome variable nor is anything known about the relationship between the observations in the data set. In many situations, however, information about the clusters is available in addition to the values of the features. For example, the cluster labels of some observations may be known, or certain observations may be known to belong to the same cluster. In other cases, one may wish to identify clusters that are associated with a particular outcome variable. This review describes several clustering algorithms (known as “semi-supervised clustering” methods) that can be applied in these situations. The majority of these methods are modifications of the popular k-means clustering method, and several of them will be described in detail. A brief description of some other semi-supervised clustering algorithms is also provided. PMID:24729830

Manual of Scaling Methods

NASA Technical Reports Server (NTRS)

Bond, Thomas H. (Technical Monitor); Anderson, David N.

2004-01-01

This manual reviews the derivation of the similitude relationships believed to be important to ice accretion and examines ice-accretion data to evaluate their importance. Both size scaling and test-condition scaling methods employing the resulting similarity parameters are described, and experimental icing tests performed to evaluate scaling methods are reviewed with results. The material included applies primarily to unprotected, unswept geometries, but some discussion of how to approach other situations is included as well. The studies given here and scaling methods considered are applicable only to Appendix-C icing conditions. Nearly all of the experimental results presented have been obtained in sea-level tunnels. Recommendations are given regarding which scaling methods to use for both size scaling and test-condition scaling, and icing test results are described to support those recommendations. Facility limitations and size-scaling restrictions are discussed. Finally, appendices summarize the air, water and ice properties used in NASA scaling studies, give expressions for each of the similarity parameters used and provide sample calculations for the size-scaling and test-condition scaling methods advocated.

The q-G method : A q-version of the Steepest Descent method for global optimization.

PubMed

Soterroni, Aline C; Galski, Roberto L; Scarabello, Marluce C; Ramos, Fernando M

2015-01-01

In this work, the q-Gradient (q-G) method, a q-version of the Steepest Descent method, is presented. The main idea behind the q-G method is the use of the negative of the q-gradient vector of the objective function as the search direction. The q-gradient vector, or simply the q-gradient, is a generalization of the classical gradient vector based on the concept of Jackson's derivative from the q-calculus. Its use provides the algorithm an effective mechanism for escaping from local minima. The q-G method reduces to the Steepest Descent method when the parameter q tends to 1. The algorithm has three free parameters and it is implemented so that the search process gradually shifts from global exploration in the beginning to local exploitation in the end. We evaluated the q-G method on 34 test functions, and compared its performance with 34 optimization algorithms, including derivative-free algorithms and the Steepest Descent method. Our results show that the q-G method is competitive and has a great potential for solving multimodal optimization problems.

Method of making alkyl esters

DOEpatents

Elliott, Brian

2010-09-14

Methods of making alkyl esters are described herein. The methods are capable of using raw, unprocessed, low-cost feedstocks and waste grease. Generally, the method involves converting a glyceride source to a fatty acid composition and esterifying the fatty acid composition to make alkyl esters. In an embodiment, a method of making alkyl esters comprises providing a glyceride source. The method further comprises converting the glyceride source to a fatty acid composition comprising free fatty acids and less than about 1% glyceride by mass. Moreover, the method comprises esterifying the fatty acid composition in the presence of a solid acid catalyst at a temperature ranging firm about 70.degree. C. to about 120.degree. C. to produce alkyl esters, such that at least 85% of the free fatty acids are converted to alkyl esters. The method also incorporates the use of packed bed reactors for glyceride conversion and/or fatty acid esterification to make alkyl esters.

SAM Biotoxin Methods Query

EPA Pesticide Factsheets

Laboratories measuring target biotoxin analytes in environmental samples can use this online query tool to identify analytical methods included in EPA's Selected Analytical Methods for Environmental Remediation and Recovery for select biotoxins.

SAM Radiochemical Methods Query

EPA Pesticide Factsheets

Laboratories measuring target radiochemical analytes in environmental samples can use this online query tool to identify analytical methods in EPA's Selected Analytical Methods for Environmental Remediation and Recovery for select radiochemical analytes.

SAM Chemical Methods Query

EPA Pesticide Factsheets

Laboratories measuring target chemical, radiochemical, pathogens, and biotoxin analytes in environmental samples can use this online query tool to identify analytical methods in EPA's Selected Analytical Methods for Environmental Remediation and Recovery

Implementing EPA Method 537

EPA Science Inventory

This presentation describes EPA Method 537 for the analysis of 14 perfluorinated alkyl acids in drinking water as well as the challenges associated with preparing a laboratory for analysis using Method 537.

Using the Fusion Proximal Area Method and Gravity Method to Identify Areas with Physician Shortages

PubMed Central

Xiong, Xuechen; Jin, Chao; Chen, Haile; Luo, Li

2016-01-01

Objectives This paper presents a geographic information system (GIS)-based proximal area method and gravity method for identifying areas with physician shortages. The innovation of this paper is that it uses the appropriate methods to discover each type of health resource and then integrates all these methods to assess spatial access to health resources using population distribution data. In this way, spatial access to health resources for an entire city can be visualized in one neat package, which can help health policy makers quickly comprehend realistic distributions of health resources at a macro level. Methods First, classify health resources according to the trade areas of the patients they serve. Second, apply an appropriate method to each different type of health resource to measure spatial access to those resources. Third, integrate all types of access using population distribution data. Results In case study of Shanghai with the fusion method, areas with physician shortages are located primarily in suburban districts, especially in district junction areas. The result suggests that the government of Shanghai should pay more attention to these areas by investing in new or relocating existing health resources. Conclusion The fusion method is demonstrated to be more accurate and practicable than using a single method to assess spatial access to health resources. PMID:27695105

Division of methods for counting helminths' eggs and the problem of efficiency of these methods.

PubMed

Jaromin-Gleń, Katarzyna; Kłapeć, Teresa; Łagód, Grzegorz; Karamon, Jacek; Malicki, Jacek; Skowrońska, Agata; Bieganowski, Andrzej

2017-03-21

From the sanitary and epidemiological aspects, information concerning the developmental forms of intestinal parasites, especially the eggs of helminths present in our environment in: water, soil, sandpits, sewage sludge, crops watered with wastewater are very important. The methods described in the relevant literature may be classified in various ways, primarily according to the methodology of the preparation of samples from environmental matrices prepared for analysis, and the sole methods of counting and chambers/instruments used for this purpose. In addition, there is a possibility to perform the classification of the research methods analyzed from the aspect of the method and time of identification of the individuals counted, or the necessity for staining them. Standard methods for identification of helminths' eggs from environmental matrices are usually characterized by low efficiency, i.e. from 30% to approximately 80%. The efficiency of the method applied may be measured in a dual way, either by using the method of internal standard or the 'Split/Spike' method. While measuring simultaneously in an examined object the efficiency of the method and the number of eggs, the 'actual' number of eggs may be calculated by multiplying the obtained value of the discovered eggs of helminths by inverse efficiency.

More than Method?: A Discussion of Paradigm Differences within Mixed Methods Research

ERIC Educational Resources Information Center

Harrits, Gitte Sommer

2011-01-01

This article challenges the idea that mixed methods research (MMR) constitutes a coherent research paradigm and explores how different research paradigms exist within MMR. Tracing paradigmatic differences at the level of methods, ontology, and epistemology, two MMR strategies are discussed: nested analysis, recently presented by the American…

Highly efficient preparation of sphingoid bases from glucosylceramides by chemoenzymatic method[S

PubMed Central

Gowda, Siddabasave Gowda B.; Usuki, Seigo; Hammam, Mostafa A. S.; Murai, Yuta; Igarashi, Yasuyuki; Monde, Kenji

2016-01-01

Sphingoid base derivatives have attracted increasing attention as promising chemotherapeutic candidates against lifestyle diseases such as diabetes and cancer. Natural sphingoid bases can be a potential resource instead of those derived by time-consuming total organic synthesis. In particular, glucosylceramides (GlcCers) in food plants are enriched sources of sphingoid bases, differing from those of animals. Several chemical methodologies to transform GlcCers to sphingoid bases have already investigated; however, these conventional methods using acid or alkaline hydrolysis are not efficient due to poor reaction yield, producing complex by-products and resulting in separation problems. In this study, an extremely efficient and practical chemoenzymatic transformation method has been developed using microwave-enhanced butanolysis of GlcCers and a large amount of readily available almond β-glucosidase for its deglycosylation reaction of lysoGlcCers. The method is superior to conventional acid/base hydrolysis methods in its rapidity and its reaction cleanness (no isomerization, no rearrangement) with excellent overall yield. PMID:26667669

Seismic Methods

EPA Pesticide Factsheets

Seismic methods are the most commonly conducted geophysical surveys for engineering investigations. Seismic refraction provides engineers and geologists with the most basic of geologic data via simple procedures with common equipment.

Pivot methods for global optimization

NASA Astrophysics Data System (ADS)

Stanton, Aaron Fletcher

A new algorithm is presented for the location of the global minimum of a multiple minima problem. It begins with a series of randomly placed probes in phase space, and then uses an iterative redistribution of the worst probes into better regions of phase space until a chosen convergence criterion is fulfilled. The method quickly converges, does not require derivatives, and is resistant to becoming trapped in local minima. Comparison of this algorithm with others using a standard test suite demonstrates that the number of function calls has been decreased conservatively by a factor of about three with the same degrees of accuracy. Two major variations of the method are presented, differing primarily in the method of choosing the probes that act as the basis for the new probes. The first variation, termed the lowest energy pivot method, ranks all probes by their energy and keeps the best probes. The probes being discarded select from those being kept as the basis for the new cycle. In the second variation, the nearest neighbor pivot method, all probes are paired with their nearest neighbor. The member of each pair with the higher energy is relocated in the vicinity of its neighbor. Both methods are tested against a standard test suite of functions to determine their relative efficiency, and the nearest neighbor pivot method is found to be the more efficient. A series of Lennard-Jones clusters is optimized with the nearest neighbor method, and a scaling law is found for cpu time versus the number of particles in the system. The two methods are then compared more explicitly, and finally a study in the use of the pivot method for solving the Schroedinger equation is presented. The nearest neighbor method is found to be able to solve the ground state of the quantum harmonic oscillator from a pure random initialization of the wavefunction.

LEAKAGE TESTING METHOD

DOEpatents

McAdams, Wm.A.; Foss, M.H.

1958-08-12

A method of testing containers for leaks is described, particularly the testing of containers or cans in which the uranium slugs for nuelear reactors are jacketed. This method involves the immersion of the can in water under l50 pounds of pressure, then removing, drying, and coating the can with anhydrous copper sulfate. Amy water absorbed by the can under pressure will exude and discolor the copper sulfate in the area about the leak.

Thin, Conductive Permafrost Surrounding Lake Fryxell Indicates Salts From Past Lakes, McMurdo Dry Valleys, Antarctica

NASA Astrophysics Data System (ADS)

Foley, N.; Tulaczyk, S. M.; Gooseff, M. N.; Myers, K. F.; Doran, P. T.; Auken, E.; Dugan, H. A.; Mikucki, J.; Virginia, R. A.

2017-12-01

In the McMurdo Dry Valleys (MDV), permafrost should be thick and liquid water rare. However, despite the well below zero mean annual temperature in this cryospheric desert, liquid water can be found in lakes, summer melt streams, subglacial outflow, and - recent work has shown - underneath anomalously thin permafrost. In part, this niche hydrosphere is maintained by the presence of salts, which depress the freezing point of water to perhaps as cold as -10° Celsius. We detected widespread salty water across the MDV in lakes and at depth using a helicopter-borne Time Domain Electromagnetic (TDEM) sensor. By using the presence of brines to mark the transition from frozen permafrost (near the surface) to unfrozen ground (at depth), we have created a map of permafrost thickness in Lower Taylor Valley (LTV), a large MDV with a complex history of glaciation and occupation by lakes. Our results show that permafrost is thinner ( 200m) than would be expected based on geothermal gradient measurements (up to 1000m), a result of the freezing point depression caused by salt and potentially enhanced by an unfinished transient freezing process. Near Lake Fryxell, a large, brackish lake in the center of LTV, permafrost is very thin (about 30-40m) and notably more electrically conductive than more distal permafrost. This thin ring of conductive permafrost surrounding the lake basin most likely reflects the high presence of salts in the subsurface, preventing complete freezing. These salts may be a remnant of the salty bottom waters of a historic larger lake (LGM glacially dammed Lake Washburn) or the remnant of salty basal water from a past advance of Taylor Glacier, which now sits many km up-valley but is known to contain brines which currently flow onto the surface and directly into the subsurface aquifer.

The Schwinger Variational Method

NASA Technical Reports Server (NTRS)

Huo, Winifred M.

1995-01-01

Variational methods have proven invaluable in theoretical physics and chemistry, both for bound state problems and for the study of collision phenomena. For collisional problems they can be grouped into two types: those based on the Schroedinger equation and those based on the Lippmann-Schwinger equation. The application of the Schwinger variational (SV) method to e-molecule collisions and photoionization has been reviewed previously. The present chapter discusses the implementation of the SV method as applied to e-molecule collisions.

Method for inducing hypothermia

DOEpatents

Becker, Lance B.; Hoek, Terry Vanden; Kasza, Kenneth E.

2003-04-15

Systems for phase-change particulate slurry cooling equipment and methods to induce hypothermia in a patient through internal and external cooling are provided. Subcutaneous, intravascular, intraperitoneal, gastrointestinal, and lung methods of cooling are carried out using saline ice slurries or other phase-change slurries compatible with human tissue. Perfluorocarbon slurries or other slurry types compatible with human tissue are used for pulmonary cooling. And traditional external cooling methods are improved by utilizing phase-change slurry materials in cooling caps and torso blankets.

Method for inducing hypothermia

DOEpatents

Becker, Lance B [Chicago, IL; Hoek, Terry Vanden [Chicago, IL; Kasza, Kenneth E [Palos Park, IL

2008-09-09

Systems for phase-change particulate slurry cooling equipment and methods to induce hypothermia in a patient through internal and external cooling are provided. Subcutaneous, intravascular, intraperitoneal, gastrointestinal, and lung methods of cooling are carried out using saline ice slurries or other phase-change slurries compatible with human tissue. Perfluorocarbon slurries or other slurry types compatible with human tissue are used for pulmonary cooling. And traditional external cooling methods are improved by utilizing phase-change slurry materials in cooling caps and torso blankets.

Method for inducing hypothermia

DOEpatents

Becker, Lance B.; Hoek, Terry Vanden; Kasza, Kenneth E.

2005-11-08

Systems for phase-change particulate slurry cooling equipment and methods to induce hypothermia in a patient through internal and external cooling are provided. Subcutaneous, intravascular, intraperitoneal, gastrointestinal, and lung methods of cooling are carried out using saline ice slurries or other phase-change slurries compatible with human tissue. Perfluorocarbon slurries or other slurry types compatible with human tissue are used for pulmonary cooling. And traditional external cooling methods are improved by utilizing phase-change slurry materials in cooling caps and torso blankets.

The spaced antenna drift method

NASA Technical Reports Server (NTRS)

Hocking, W. K.

1983-01-01

The spaced antenna drift method is a simple and relatively inexpensive method for determination of atmospheric wind velocities using radars. The technique has been extensively tested in the mesosphere at high and medium frequencies, and found to give reliable results. Recently, the method has also been applied to VHF observations of the troposphere and stratosphere, and results appear to be reliable. This paper discusses briefly the principle of the method, and investigates both its strengths and weaknesses. Some discussions concerning criticisms of the technique are also given, and it is concluded that while these criticisms may be of some concern at times, appropriate care can ensure that the method is at least as viable as any other method of remote wind measurement. At times, the technique has definite advantages.

Construction of exponentially fitted symplectic Runge-Kutta-Nyström methods from partitioned Runge-Kutta methods

NASA Astrophysics Data System (ADS)

Monovasilis, Theodore; Kalogiratou, Zacharoula; Simos, T. E.

2014-10-01

In this work we derive exponentially fitted symplectic Runge-Kutta-Nyström (RKN) methods from symplectic exponentially fitted partitioned Runge-Kutta (PRK) methods methods (for the approximate solution of general problems of this category see [18] - [40] and references therein). We construct RKN methods from PRK methods with up to five stages and fourth algebraic order.

Understanding common statistical methods, Part I: descriptive methods, probability, and continuous data.

PubMed

Skinner, Carl G; Patel, Manish M; Thomas, Jerry D; Miller, Michael A

2011-01-01

Statistical methods are pervasive in medical research and general medical literature. Understanding general statistical concepts will enhance our ability to critically appraise the current literature and ultimately improve the delivery of patient care. This article intends to provide an overview of the common statistical methods relevant to medicine.

High-speed 3D imaging using digital binary defocusing method vs sinusoidal method

NASA Astrophysics Data System (ADS)

Zhang, Song; Hyun, Jae-Sang; Li, Beiwen

2017-02-01

This paper presents our research findings on high-speed 3D imaging using digital light processing (DLP) technologies. In particular, we compare two different sinusoidal fringe generation techniques using the DLP projection devices: direct projection of 8-bit computer generated sinusoidal patterns (a.k.a, the sinusoidal method), and the creation of sinusoidal patterns by defocusing binary patterns (a.k.a., the binary defocusing method). This paper mainly examines their performance on high-accuracy measurement applications under precisely controlled settings. Two different projection systems were tested in this study: the commercially available inexpensive projector, and the DLP development kit. Experimental results demonstrated that the binary defocusing method always outperforms the sinusoidal method if a sufficient number of phase-shifted fringe patterns can be used.

The Parker-Sochacki Method--A Powerful New Method for Solving Systems of Differential Equations

NASA Astrophysics Data System (ADS)

Rudmin, Joseph W.

2001-04-01

The Parker-Sochacki Method--A Powerful New Method for Solving Systems of Differential Equations Joseph W. Rudmin (Physics Dept, James Madison University) A new system of solving systems of differential equations will be presented, which has been developed by J. Edgar Parker and James Sochacki, of the James Madison University Mathematics Department. The method produces MacClaurin Series solutions to systems of differential equations, with the coefficients in either algebraic or numerical form. The method yields high-degree solutions: 20th degree is easily obtainable. It is conceptually simple, fast, and extremely general. It has been applied to over a hundred systems of differential equations, some of which were previously unsolved, and has yet to fail to solve any system for which the MacClaurin series converges. The method is non-recursive: each coefficient in the series is calculated just once, in closed form, and its accuracy is limited only by the digital accuracy of the computer. Although the original differential equations may include any mathematical functions, the computational method includes ONLY the operations of addition, subtraction, and multiplication. Furthermore, it is perfectly suited to parallel -processing computer languages. Those who learn this system will never use Runge-Kutta or predictor-corrector methods again. Examples will be presented, including the classical many-body problem.

Study of comparison between Ultra-high Frequency (UHF) method and ultrasonic method on PD detection for GIS

NASA Astrophysics Data System (ADS)

Li, Yanran; Chen, Duo; Li, Li; Zhang, Jiwei; Li, Guang; Liu, Hongxia

2017-11-01

GIS (gas insulated switchgear), is an important equipment in power system. Partial discharge plays an important role in detecting the insulation performance of GIS. UHF method and ultrasonic method frequently used in partial discharge (PD) detection for GIS. However, few studies have been conducted on comparison of this two methods. From the view point of safety, it is necessary to investigate UHF method and ultrasonic method for partial discharge in GIS. This paper presents study aimed at clarifying the effect of UHF method and ultrasonic method for partial discharge caused by free metal particles in GIS. Partial discharge tests were performed in laboratory simulated environment. Obtained results show the ability of anti-interference of signal detection and the accuracy of fault localization for UHF method and ultrasonic method. A new method based on UHF method and ultrasonic method of PD detection for GIS is proposed in order to greatly enhance the ability of anti-interference of signal detection and the accuracy of detection localization.

Designing Class Methods from Dataflow Diagrams

NASA Astrophysics Data System (ADS)

Shoval, Peretz; Kabeli-Shani, Judith

A method for designing the class methods of an information system is described. The method is part of FOOM - Functional and Object-Oriented Methodology. In the analysis phase of FOOM, two models defining the users' requirements are created: a conceptual data model - an initial class diagram; and a functional model - hierarchical OO-DFDs (object-oriented dataflow diagrams). Based on these models, a well-defined process of methods design is applied. First, the OO-DFDs are converted into transactions, i.e., system processes that supports user task. The components and the process logic of each transaction are described in detail, using pseudocode. Then, each transaction is decomposed, according to well-defined rules, into class methods of various types: basic methods, application-specific methods and main transaction (control) methods. Each method is attached to a proper class; messages between methods express the process logic of each transaction. The methods are defined using pseudocode or message charts.

Membranes, methods of making membranes, and methods of separating gases using membranes

DOEpatents

Ho, W. S. Winston

2012-10-02

Membranes, methods of making membranes, and methods of separating gases using membranes are provided. The membranes can include at least one hydrophilic polymer, at least one cross-linking agent, at least one base, and at least one amino compound. The methods of separating gases using membranes can include contacting a gas stream containing at least one of CO.sub.2, H.sub.2S, and HCl with one side of a nonporous and at least one of CO.sub.2, H.sub.2S, and HCl selectively permeable membrane such that at least one of CO.sub.2, H.sub.2S, and HCl is selectively transported through the membrane.

Method of forming aluminum oxynitride material and bodies formed by such methods

DOEpatents

Bakas, Michael P [Ammon, ID; Lillo, Thomas M [Idaho Falls, ID; Chu, Henry S [Idaho Falls, ID

2010-11-16

Methods of forming aluminum oxynitride (AlON) materials include sintering green bodies comprising aluminum orthophosphate or another sacrificial material therein. Such green bodies may comprise aluminum, oxygen, and nitrogen in addition to the aluminum orthophosphate. For example, the green bodies may include a mixture of aluminum oxide, aluminum nitride, and aluminum orthophosphate or another sacrificial material. Additional methods of forming aluminum oxynitride (AlON) materials include sintering a green body including a sacrificial material therein, using the sacrificial material to form pores in the green body during sintering, and infiltrating the pores formed in the green body with a liquid infiltrant during sintering. Bodies are formed using such methods.

Method for producing smooth inner surfaces

DOEpatents

Cooper, Charles A.

2016-05-17

The invention provides a method for preparing superconducting cavities, the method comprising causing polishing media to tumble by centrifugal barrel polishing within the cavities for a time sufficient to attain a surface smoothness of less than 15 nm root mean square roughness over approximately a 1 mm.sup.2 scan area. The method also provides for a method for preparing superconducting cavities, the method comprising causing polishing media bound to a carrier to tumble within the cavities. The method also provides for a method for preparing superconducting cavities, the method comprising causing polishing media in a slurry to tumble within the cavities.

Interior-Point Methods for Linear Programming: A Challenge to the Simplex Method

DTIC Science & Technology

1988-07-01

subsequently found that the method was first proposed by Dikin in 1967 [6]. Search directions are generated by the same system (5). Any hint of quadratic...1982). Inexact Newton methods, SIAM Journal on Numerical Analysis 19, 400-408. [6] I. I. Dikin (1967). Iterative solution of problems of linear and

Unidirectional Fabric Drape Testing Method

PubMed Central

Mei, Zaihuan; Yang, Jingzhi; Zhou, Ting; Zhou, Hua

2015-01-01

In most cases, fabrics such as curtains, skirts, suit pants and so on are draped under their own gravity parallel to fabric plane while the gravity is perpendicular to fabric plane in traditional drape testing method. As a result, it does not conform to actual situation and the test data is not convincing enough. To overcome this problem, this paper presents a novel method which simulates the real mechanical conditions and ensures the gravity is parallel to the fabric plane. This method applied a low-cost Kinect Sensor device to capture the 3-dimensional (3D) drape profile, thus we obtained the drape degree parameters and aesthetic parameters by 3D reconstruction and image processing and analysis techniques. The experiment was conducted on our self-devised drape-testing instrument by choosing different kinds of weave structure fabrics as our testing samples and the results were compared with those of traditional method and subjective evaluation. Through regression and correlation analysis we found that this novel testing method was significantly correlated with the traditional and subjective evaluation method. We achieved a new, non-contact 3D measurement method for drape testing, namely unidirectional fabric drape testing method. This method is more suitable for evaluating drape behavior because it is more in line with actual mechanical conditions of draped fabrics and has a well consistency with the requirements of visual and aesthetic style of fabrics. PMID:26600387

Microencapsulation and Electrostatic Processing Method

NASA Technical Reports Server (NTRS)

Morrison, Dennis R. (Inventor); Mosier, Benjamin (Inventor)

2000-01-01

Methods are provided for forming spherical multilamellar microcapsules having alternating hydrophilic and hydrophobic liquid layers, surrounded by flexible, semi-permeable hydrophobic or hydrophilic outer membranes which can be tailored specifically to control the diffusion rate. The methods of the invention rely on low shear mixing and liquid-liquid diffusion process and are particularly well suited for forming microcapsules containing both hydrophilic and hydrophobic drugs. These methods can be carried out in the absence of gravity and do not rely on density-driven phase separation, mechanical mixing or solvent evaporation phases. The methods include the process of forming, washing and filtering microcapsules. In addition, the methods contemplate coating microcapsules with ancillary coatings using an electrostatic field and free fluid electrophoresis of the microcapsules. The microcapsules produced by such methods are particularly useful in the delivery of pharmaceutical compositions.

Negotiating a Systems Development Method

NASA Astrophysics Data System (ADS)

Karlsson, Fredrik; Hedström, Karin

Systems development methods (or methods) are often applied in tailored version to fit the actual situation. Method tailoring is in most the existing literature viewed as either (a) a highly rational process with the method engineer as the driver where the project members are passive information providers or (b) an unstructured process where the systems developer makes individual choices, a selection process without any driver. The purpose of this chapter is to illustrate that important design decisions during method tailoring are made by project members through negotiation. The study has been carried out using the perspective of actor-network theory. Our narratives depict method tailoring as more complex than (a) and (b) show the driver role rotates between the project members, and design decisions are based on influences from several project members. However, these design decisions are not consensus decisions.

Methods for purifying carbon materials

DOEpatents

Dailly, Anne [Pasadena, CA; Ahn, Channing [Pasadena, CA; Yazami, Rachid [Los Angeles, CA; Fultz, Brent T [Pasadena, CA

2009-05-26

Methods of purifying samples are provided that are capable of removing carbonaceous and noncarbonaceous impurities from a sample containing a carbon material having a selected structure. Purification methods are provided for removing residual metal catalyst particles enclosed in multilayer carbonaceous impurities in samples generate by catalytic synthesis methods. Purification methods are provided wherein carbonaceous impurities in a sample are at least partially exfoliated, thereby facilitating subsequent removal of carbonaceous and noncarbonaceous impurities from the sample. Methods of purifying carbon nanotube-containing samples are provided wherein an intercalant is added to the sample and subsequently reacted with an exfoliation initiator to achieve exfoliation of carbonaceous impurities.

Optical measurement methods in thermogasdynamics

NASA Technical Reports Server (NTRS)

Stursberg, K.; Erhardt, K.; Krahr, W.; Becker, M.

1978-01-01

A review is presented of a number of optical methods of flow measurements. Consideration is given to such spectroscopic methods as emission and absorption techniques, electron beam-stimulated fluorescence, and light scattering - Rayleigh, Raman and Mie - methods. The following visualization methods are also discussed: shadow photography, schlieren photography, interferometry, holographic interferometry, laser anemometry, particle holography, and electron-excitation imaging. A large bibliography is presented and the work is copiously illustrated with figures and photographs.

Methods for Equating Mental Tests.

DTIC Science & Technology

1984-11-01

1983) compared conventional and IRT methods for equating the Test of English as a Foreign Language ( TOEFL ) after chaining. Three conventional and...three IRT equating methods were examined in this study; two sections of TOEFL were each (separately) equated. The IRT methods included the following: (a...group. A separate base form was established for each of the six equating methods. Instead of equating the base-form TOEFL to itself, the last (eighth

Panel methods: An introduction

NASA Technical Reports Server (NTRS)

Erickson, Larry L.

1990-01-01

Panel methods are numerical schemes for solving (the Prandtl-Glauert equation) for linear, inviscid, irrotational flow about aircraft flying at subsonic or supersonic speeds. The tools at the panel-method user's disposal are (1) surface panels of source-doublet-vorticity distributions that can represent nearly arbitrary geometry, and (2) extremely versatile boundary condition capabilities that can frequently be used for creative modeling. Panel-method capabilities and limitations, basic concepts common to all panel-method codes, different choices that were made in the implementation of these concepts into working computer programs, and various modeling techniques involving boundary conditions, jump properties, and trailing wakes are discussed. An approach for extending the method to nonlinear transonic flow is also presented. Three appendices supplement the main test. In appendix 1, additional detail is provided on how the basic concepts are implemented into a specific computer program (PANAIR). In appendix 2, it is shown how to evaluate analytically the fundamental surface integral that arises in the expressions for influence-coefficients, and evaluate its jump property. In appendix 3, a simple example is used to illustrate the so-called finite part of the improper integrals.

Earth analysis methods, subsurface feature detection methods, earth analysis devices, and articles of manufacture

DOEpatents

West, Phillip B [Idaho Falls, ID; Novascone, Stephen R [Idaho Falls, ID; Wright, Jerry P [Idaho Falls, ID

2012-05-29

Earth analysis methods, subsurface feature detection methods, earth analysis devices, and articles of manufacture are described. According to one embodiment, an earth analysis method includes engaging a device with the earth, analyzing the earth in a single substantially lineal direction using the device during the engaging, and providing information regarding a subsurface feature of the earth using the analysis.

Earth analysis methods, subsurface feature detection methods, earth analysis devices, and articles of manufacture

DOEpatents

West, Phillip B [Idaho Falls, ID; Novascone, Stephen R [Idaho Falls, ID; Wright, Jerry P [Idaho Falls, ID

2011-09-27

Earth analysis methods, subsurface feature detection methods, earth analysis devices, and articles of manufacture are described. According to one embodiment, an earth analysis method includes engaging a device with the earth, analyzing the earth in a single substantially lineal direction using the device during the engaging, and providing information regarding a subsurface feature of the earth using the analysis.

SW-846 Method Style Guide

EPA Pesticide Factsheets

This style guide is for use by developers of new methods for SW-846 and editors of existing SW-846 methods. Its use will help assure consistent method format and minimize editorial errors during the development and maintenance of SW-846.

Proposed Revisions to Method 202

EPA Pesticide Factsheets

EPA is proposing the following revisions to Method 202: Revisions to the procedures for determining the systematic error of the method, which is used to correct the results of the measurements made using this method; Removes some procedural options to

Ensemble Data Mining Methods

NASA Technical Reports Server (NTRS)

Oza, Nikunj C.

2004-01-01

Ensemble Data Mining Methods, also known as Committee Methods or Model Combiners, are machine learning methods that leverage the power of multiple models to achieve better prediction accuracy than any of the individual models could on their own. The basic goal when designing an ensemble is the same as when establishing a committee of people: each member of the committee should be as competent as possible, but the members should be complementary to one another. If the members are not complementary, Le., if they always agree, then the committee is unnecessary---any one member is sufficient. If the members are complementary, then when one or a few members make an error, the probability is high that the remaining members can correct this error. Research in ensemble methods has largely revolved around designing ensembles consisting of competent yet complementary models.

Polynomial Supertree Methods Revisited

PubMed Central

Brinkmeyer, Malte; Griebel, Thasso; Böcker, Sebastian

2011-01-01

Supertree methods allow to reconstruct large phylogenetic trees by combining smaller trees with overlapping leaf sets into one, more comprehensive supertree. The most commonly used supertree method, matrix representation with parsimony (MRP), produces accurate supertrees but is rather slow due to the underlying hard optimization problem. In this paper, we present an extensive simulation study comparing the performance of MRP and the polynomial supertree methods MinCut Supertree, Modified MinCut Supertree, Build-with-distances, PhySIC, PhySIC_IST, and super distance matrix. We consider both quality and resolution of the reconstructed supertrees. Our findings illustrate the tradeoff between accuracy and running time in supertree construction, as well as the pros and cons of voting- and veto-based supertree approaches. Based on our results, we make some general suggestions for supertree methods yet to come. PMID:22229028

Cleaning method and apparatus

DOEpatents

Jackson, D.D.; Hollen, R.M.

1981-02-27

A method of very thoroughly and quikcly cleaning a guaze electrode used in chemical analyses is given, as well as an automobile cleaning apparatus which makes use of the method. The method generates very little waste solution, and this is very important in analyzing radioactive materials, especially in aqueous solutions. The cleaning apparatus can be used in a larger, fully automated controlled potential coulometric apparatus. About 99.98% of a 5 mg plutonium sample was removed in less than 3 minutes, using only about 60 ml of rinse solution and two main rinse steps.

Methods of flash sintering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Raj, Rishi; Cologna, Marco; Francis, John S.

2016-05-10

This disclosure provides methods of flash sintering and compositions created by these methods. Methods for sintering multilayered bodies are provided in which a sintered body is produced in less than one minute. In one aspect, each layer is of a different composition, and may be constituted wholly from a ceramic or from a combination of ceramic and metallic particles. When the body includes a layer of an anode composition, a layer of an electrolyte composition and a layer of a cathode composition, the sintered body can be used to produce a solid oxide fuel cell.

Method of sound synthesis

DOEpatents

Miner, Nadine E.; Caudell, Thomas P.

2004-06-08

A sound synthesis method for modeling and synthesizing dynamic, parameterized sounds. The sound synthesis method yields perceptually convincing sounds and provides flexibility through model parameterization. By manipulating model parameters, a variety of related, but perceptually different sounds can be generated. The result is subtle changes in sounds, in addition to synthesis of a variety of sounds, all from a small set of models. The sound models can change dynamically according to changes in the simulation environment. The method is applicable to both stochastic (impulse-based) and non-stochastic (pitched) sounds.

Proven Weight Loss Methods

MedlinePlus

Fact Sheet Proven Weight Loss Methods What can weight loss do for you? Losing weight can improve your health in a number of ways. It can lower ... at www.hormone.org/Spanish . Proven Weight Loss Methods Fact Sheet www.hormone.org

Method of forming nanodielectrics

DOEpatents

Tuncer, Enis [Knoxville, TN; Polyzos, Georgios [Oak Ridge, TN

2014-01-07

A method of making a nanoparticle filled dielectric material. The method includes mixing nanoparticle precursors with a polymer material and reacting the nanoparticle mixed with the polymer material to form nanoparticles dispersed within the polymer material to form a dielectric composite.

Mixed methods for telehealth research.

PubMed

Caffery, Liam J; Martin-Khan, Melinda; Wade, Victoria

2017-10-01

Mixed methods research is important to health services research because the integrated qualitative and quantitative investigation can give a more comprehensive understanding of complex interventions such as telehealth than can a single-method study. Further, mixed methods research is applicable to translational research and program evaluation. Study designs relevant to telehealth research are described and supported by examples. Quality assessment tools, frameworks to assist in the reporting and review of mixed methods research, and related methodologies are also discussed.

Vortex methods and vortex statistics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chorin, A.J.

Vortex methods originated from the observation that in incompressible, inviscid, isentropic flow vorticity (or, more accurately, circulation) is a conserved quantity, as can be readily deduced from the absence of tangential stresses. Thus if the vorticity is known at time t = 0, one can deduce the flow at a later time by simply following it around. In this narrow context, a vortex method is a numerical method that makes use of this observation. Even more generally, the analysis of vortex methods leads, to problems that are closely related to problems in quantum physics and field theory, as well asmore » in harmonic analysis. A broad enough definition of vortex methods ends up by encompassing much of science. Even the purely computational aspects of vortex methods encompass a range of ideas for which vorticity may not be the best unifying theme. The author restricts himself in these lectures to a special class of numerical vortex methods, those that are based on a Lagrangian transport of vorticity in hydrodynamics by smoothed particles (``blobs``) and those whose understanding contributes to the understanding of blob methods. Vortex methods for inviscid flow lead to systems of ordinary differential equations that can be readily clothed in Hamiltonian form, both in three and two space dimensions, and they can preserve exactly a number of invariants of the Euler equations, including topological invariants. Their viscous versions resemble Langevin equations. As a result, they provide a very useful cartoon of statistical hydrodynamics, i.e., of turbulence, one that can to some extent be analyzed analytically and more importantly, explored numerically, with important implications also for superfluids, superconductors, and even polymers. In the authors view, vortex ``blob`` methods provide the most promising path to the understanding of these phenomena.« less

Phosphorescent compositions, methods of making the compositions, and methods of using the compositions

DOEpatents

Jia, Weiyi; Wang, Xiaojun; Yen, William; Yen, Laurel C.; Jia, George D.

2012-12-04

Compositions, methods of making compositions, materials including compositions, crayons including compositions, paint including compositions, ink including compositions, waxes including compositions, polymers including compositions, vesicles including the compositions, methods of making each, and the like are disclosed.

Phosphorescent compositions, methods of making the compositions, and methods of using the compositions

DOEpatents

Jia, Weiyi; Wang, Xiaojun; Jia, George D.; Lewis, Linda; Yen, Laurel C.

2014-06-24

Compositions, methods of making compositions, materials including compositions, crayons including compositions, paint including compositions, ink including compositions, waxes including compositions, polymers including compositions, vesicles including the compositions, methods of making each, and the like are disclosed.

Text-in-context: a method for extracting findings in mixed-methods mixed research synthesis studies.

PubMed

Sandelowski, Margarete; Leeman, Jennifer; Knafl, Kathleen; Crandell, Jamie L

2013-06-01

Our purpose in this paper is to propose a new method for extracting findings from research reports included in mixed-methods mixed research synthesis studies. International initiatives in the domains of systematic review and evidence synthesis have been focused on broadening the conceptualization of evidence, increased methodological inclusiveness and the production of evidence syntheses that will be accessible to and usable by a wider range of consumers. Initiatives in the general mixed-methods research field have been focused on developing truly integrative approaches to data analysis and interpretation. The data extraction challenges described here were encountered, and the method proposed for addressing these challenges was developed, in the first year of the ongoing (2011-2016) study: Mixed-Methods Synthesis of Research on Childhood Chronic Conditions and Family. To preserve the text-in-context of findings in research reports, we describe a method whereby findings are transformed into portable statements that anchor results to relevant information about sample, source of information, time, comparative reference point, magnitude and significance and study-specific conceptions of phenomena. The data extraction method featured here was developed specifically to accommodate mixed-methods mixed research synthesis studies conducted in nursing and other health sciences, but reviewers might find it useful in other kinds of research synthesis studies. This data extraction method itself constitutes a type of integration to preserve the methodological context of findings when statements are read individually and in comparison to each other. © 2012 Blackwell Publishing Ltd.

Method for isolating nucleic acids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hurt, Jr., Richard Ashley; Elias, Dwayne A.

The current disclosure provides methods and kits for isolating nucleic acid from an environmental sample. The current methods and compositions further provide methods for isolating nucleic acids by reducing adsorption of nucleic acids by charged ions and particles within an environmental sample. The methods of the current disclosure provide methods for isolating nucleic acids by releasing adsorbed nucleic acids from charged particles during the nucleic acid isolation process. The current disclosure facilitates the isolation of nucleic acids of sufficient quality and quantity to enable one of ordinary skill in the art to utilize or analyze the isolated nucleic acids formore » a wide variety of applications including, sequencing or species population analysis.« less

Methods for computing color anaglyphs

NASA Astrophysics Data System (ADS)

McAllister, David F.; Zhou, Ya; Sullivan, Sophia

2010-02-01

A new computation technique is presented for calculating pixel colors in anaglyph images. The method depends upon knowing the RGB spectral distributions of the display device and the transmission functions of the filters in the viewing glasses. It requires the solution of a nonlinear least-squares program for each pixel in a stereo pair and is based on minimizing color distances in the CIEL*a*b* uniform color space. The method is compared with several techniques for computing anaglyphs including approximation in CIE space using the Euclidean and Uniform metrics, the Photoshop method and its variants, and a method proposed by Peter Wimmer. We also discuss the methods of desaturation and gamma correction for reducing retinal rivalry.

77 FR 60985 - Ambient Air Monitoring Reference and Equivalent Methods: Designation of Three New Equivalent Methods

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-05

... Methods: Designation of Three New Equivalent Methods AGENCY: Environmental Protection Agency. ACTION: Notice of the designation of three new equivalent methods for monitoring ambient air quality. SUMMARY... equivalent methods, one for measuring concentrations of PM 2.5 , one for measuring concentrations of PM 10...

78 FR 67360 - Ambient Air Monitoring Reference and Equivalent Methods: Designation of Five New Equivalent Methods

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-12

... Methods: Designation of Five New Equivalent Methods AGENCY: Office of Research and Development; Environmental Protection Agency (EPA). ACTION: Notice of the designation of five new equivalent methods for...) has designated, in accordance with 40 CFR Part 53, five new equivalent methods, one for measuring...

Actinide extraction methods

DOEpatents

Peterman, Dean R [Idaho Falls, ID; Klaehn, John R [Idaho Falls, ID; Harrup, Mason K [Idaho Falls, ID; Tillotson, Richard D [Moore, ID; Law, Jack D [Pocatello, ID

2010-09-21

Methods of separating actinides from lanthanides are disclosed. A regio-specific/stereo-specific dithiophosphinic acid having organic moieties is provided in an organic solvent that is then contacted with an acidic medium containing an actinide and a lanthanide. The method can extend to separating actinides from one another. Actinides are extracted as a complex with the dithiophosphinic acid. Separation compositions include an aqueous phase, an organic phase, dithiophosphinic acid, and at least one actinide. The compositions may include additional actinides and/or lanthanides. A method of producing a dithiophosphinic acid comprising at least two organic moieties selected from aromatics and alkyls, each moiety having at least one functional group is also disclosed. A source of sulfur is reacted with a halophosphine. An ammonium salt of the dithiophosphinic acid product is precipitated out of the reaction mixture. The precipitated salt is dissolved in ether. The ether is removed to yield the dithiophosphinic acid.

Standard setting: comparison of two methods.

PubMed

George, Sanju; Haque, M Sayeed; Oyebode, Femi

2006-09-14

The outcome of assessments is determined by the standard-setting method used. There is a wide range of standard-setting methods and the two used most extensively in undergraduate medical education in the UK are the norm-reference and the criterion-reference methods. The aims of the study were to compare these two standard-setting methods for a multiple-choice question examination and to estimate the test-retest and inter-rater reliability of the modified Angoff method. The norm-reference method of standard-setting (mean minus 1 SD) was applied to the 'raw' scores of 78 4th-year medical students on a multiple-choice examination (MCQ). Two panels of raters also set the standard using the modified Angoff method for the same multiple-choice question paper on two occasions (6 months apart). We compared the pass/fail rates derived from the norm reference and the Angoff methods and also assessed the test-retest and inter-rater reliability of the modified Angoff method. The pass rate with the norm-reference method was 85% (66/78) and that by the Angoff method was 100% (78 out of 78). The percentage agreement between Angoff method and norm-reference was 78% (95% CI 69% - 87%). The modified Angoff method had an inter-rater reliability of 0.81-0.82 and a test-retest reliability of 0.59-0.74. There were significant differences in the outcomes of these two standard-setting methods, as shown by the difference in the proportion of candidates that passed and failed the assessment. The modified Angoff method was found to have good inter-rater reliability and moderate test-retest reliability.

An improved EMD method for modal identification and a combined static-dynamic method for damage detection

NASA Astrophysics Data System (ADS)

Yang, Jinping; Li, Peizhen; Yang, Youfa; Xu, Dian

2018-04-01

Empirical mode decomposition (EMD) is a highly adaptable signal processing method. However, the EMD approach has certain drawbacks, including distortions from end effects and mode mixing. In the present study, these two problems are addressed using an end extension method based on the support vector regression machine (SVRM) and a modal decomposition method based on the characteristics of the Hilbert transform. The algorithm includes two steps: using the SVRM, the time series data are extended at both endpoints to reduce the end effects, and then, a modified EMD method using the characteristics of the Hilbert transform is performed on the resulting signal to reduce mode mixing. A new combined static-dynamic method for identifying structural damage is presented. This method combines the static and dynamic information in an equilibrium equation that can be solved using the Moore-Penrose generalized matrix inverse. The combination method uses the differences in displacements of the structure with and without damage and variations in the modal force vector. Tests on a four-story, steel-frame structure were conducted to obtain static and dynamic responses of the structure. The modal parameters are identified using data from the dynamic tests and improved EMD method. The new method is shown to be more accurate and effective than the traditional EMD method. Through tests with a shear-type test frame, the higher performance of the proposed static-dynamic damage detection approach, which can detect both single and multiple damage locations and the degree of the damage, is demonstrated. For structures with multiple damage, the combined approach is more effective than either the static or dynamic method. The proposed EMD method and static-dynamic damage detection method offer improved modal identification and damage detection, respectively, in structures.

Methods for data classification

DOEpatents

Garrity, George [Okemos, MI; Lilburn, Timothy G [Front Royal, VA

2011-10-11

The present invention provides methods for classifying data and uncovering and correcting annotation errors. In particular, the present invention provides a self-organizing, self-correcting algorithm for use in classifying data. Additionally, the present invention provides a method for classifying biological taxa.

Comparison of microstickies measurement methods. Part I, sample preparation and measurement methods

Treesearch

Mahendra R. Doshi; Angeles Blanco; Carlos Negro; Gilles M. Dorris; Carlos C. Castro; Axel Hamann; R. Daniel Haynes; Carl Houtman; Karen Scallon; Hans-Joachim Putz; Hans Johansson; R.A. Venditti; K. Copeland; H.-M. Chang

2003-01-01

Recently, we completed a project on the comparison of macrostickies measurement methods. Based on the success of the project, we decided to embark on this new project on comparison of microstickies measurement methods. When we started this project, there were some concerns and doubts principally due to the lack of an accepted definition of microstickies. However, we...

Probabilistic methods for rotordynamics analysis

NASA Technical Reports Server (NTRS)

Wu, Y.-T.; Torng, T. Y.; Millwater, H. R.; Fossum, A. F.; Rheinfurth, M. H.

1991-01-01

This paper summarizes the development of the methods and a computer program to compute the probability of instability of dynamic systems that can be represented by a system of second-order ordinary linear differential equations. Two instability criteria based upon the eigenvalues or Routh-Hurwitz test functions are investigated. Computational methods based on a fast probability integration concept and an efficient adaptive importance sampling method are proposed to perform efficient probabilistic analysis. A numerical example is provided to demonstrate the methods.

Methods of analyzing crude oil

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cooks, Robert Graham; Jjunju, Fred Paul Mark; Li, Anyin

The invention generally relates to methods of analyzing crude oil. In certain embodiments, methods of the invention involve obtaining a crude oil sample, and subjecting the crude oil sample to mass spectrometry analysis. In certain embodiments, the method is performed without any sample pre-purification steps.

Structural Embeddings: Mechanization with Method

NASA Technical Reports Server (NTRS)

Munoz, Cesar; Rushby, John

1999-01-01

The most powerful tools for analysis of formal specifications are general-purpose theorem provers and model checkers, but these tools provide scant methodological support. Conversely, those approaches that do provide a well-developed method generally have less powerful automation. It is natural, therefore, to try to combine the better-developed methods with the more powerful general-purpose tools. An obstacle is that the methods and the tools often employ very different logics. We argue that methods are separable from their logics and are largely concerned with the structure and organization of specifications. We, propose a technique called structural embedding that allows the structural elements of a method to be supported by a general-purpose tool, while substituting the logic of the tool for that of the method. We have found this technique quite effective and we provide some examples of its application. We also suggest how general-purpose systems could be restructured to support this activity better.

Strengthening method of concrete structure

NASA Astrophysics Data System (ADS)

Inge, Wewin; Audrey; Nugroho, Sofie; Njo, Helen

2018-03-01

Building extension in Indonesia is not favored, and not many people know the advantages of the method because architects and engineers tend to lack the knowledge and experience. The aim of this paper is to explain a method on how to strengthen a concrete building structure that people can use/learn as a better way to cut potential cost and save time. The strengthening method explained in this paper is steel jacketing, providing a case study of this method in the extension of a restaurant located in Medan, Indonesia. In this study, engineers calculated that the tensile stress of the existing RC column and beam is not strong enough to reinforce the building extension applied load. Therefore, the steel jacketing method can be applied to improve the column and beam strength and ductility. The result of the case study proves that this is one of the best methods for building extension applied in Indonesia.

Integration of Gas Chromatography Mass Spectrometry Methods for Differentiating Ricin Preparation Methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wunschel, David S.; Melville, Angela M.; Ehrhardt, Christopher J.

2012-05-17

The investigation of crimes involving chemical or biological agents is infrequent, but presents unique analytical challenges. The protein toxin ricin is encountered more frequently than other agents and is found in the seeds of the castor plant Ricinus communis. Typically, the toxin is extracted from castor seeds utilizing a variety of different recipes that result in varying purity of the toxin. Moreover, these various purification steps can also leave or differentially remove a variety of exogenous and endogenous residual components with the toxin that may indicate the type and number of purification steps involved. We have applied three gas chromatographicmore » - mass spectrometric (GC-MS) based analytical methods to measure the variation in seed carbohydrates and castor oil ricinoleic acid as well as the presence of solvents used for purification. These methods were applied to the same samples prepared using four previously identified toxin preparation methods starting from four varieties of castor seeds. The individual data sets for seed carbohydrate profiles, ricinoleic acid or acetone amount each provided information capable of differentiating different types of toxin preparations across seed types. However, the integration of the data sets using multivariate factor analysis provided a clear distinction of all samples based on the preparation method and independent of the seed source. In particular the abundance of mannose, arabinose, fucose, ricinoleic acid and acetone were shown to be important differentiating factors. These complementary tools provide a more confident determination of the method of toxin preparation.« less

77 FR 55832 - Ambient Air Monitoring Reference and Equivalent Methods: Designation of a New Equivalent Method

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-11

... Methods: Designation of a New Equivalent Method AGENCY: Environmental Protection Agency. ACTION: Notice of the designation of a new equivalent method for monitoring ambient air quality. SUMMARY: Notice is... part 53, a new equivalent method for measuring concentrations of PM 2.5 in the ambient air. FOR FURTHER...

24 CFR 291.90 - Sales methods.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Sales methods. 291.90 Section 291....90 Sales methods. HUD will prescribe the terms and conditions for all methods of sale. HUD may, in... following methods of sale: (a) Future REO acquisition method. The Future Real Estate-Owned (REO) acquisition...

24 CFR 291.90 - Sales methods.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Sales methods. 291.90 Section 291....90 Sales methods. HUD will prescribe the terms and conditions for all methods of sale. HUD may, in... following methods of sale: (a) Future REO acquisition method. The Future Real Estate-Owned (REO) acquisition...

24 CFR 291.90 - Sales methods.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Sales methods. 291.90 Section 291....90 Sales methods. HUD will prescribe the terms and conditions for all methods of sale. HUD may, in... following methods of sale: (a) Future REO acquisition method. The Future Real Estate-Owned (REO) acquisition...

24 CFR 291.90 - Sales methods.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Sales methods. 291.90 Section 291....90 Sales methods. HUD will prescribe the terms and conditions for all methods of sale. HUD may, in... following methods of sale: (a) Future REO acquisition method. The Future Real Estate-Owned (REO) acquisition...

24 CFR 291.90 - Sales methods.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Sales methods. 291.90 Section 291....90 Sales methods. HUD will prescribe the terms and conditions for all methods of sale. HUD may, in... following methods of sale: (a) Future REO acquisition method. The Future Real Estate-Owned (REO) acquisition...

A Comparison of the β-Substitution Method and a Bayesian Method for Analyzing Left-Censored Data.

PubMed

Huynh, Tran; Quick, Harrison; Ramachandran, Gurumurthy; Banerjee, Sudipto; Stenzel, Mark; Sandler, Dale P; Engel, Lawrence S; Kwok, Richard K; Blair, Aaron; Stewart, Patricia A

2016-01-01

Classical statistical methods for analyzing exposure data with values below the detection limits are well described in the occupational hygiene literature, but an evaluation of a Bayesian approach for handling such data is currently lacking. Here, we first describe a Bayesian framework for analyzing censored data. We then present the results of a simulation study conducted to compare the β-substitution method with a Bayesian method for exposure datasets drawn from lognormal distributions and mixed lognormal distributions with varying sample sizes, geometric standard deviations (GSDs), and censoring for single and multiple limits of detection. For each set of factors, estimates for the arithmetic mean (AM), geometric mean, GSD, and the 95th percentile (X0.95) of the exposure distribution were obtained. We evaluated the performance of each method using relative bias, the root mean squared error (rMSE), and coverage (the proportion of the computed 95% uncertainty intervals containing the true value). The Bayesian method using non-informative priors and the β-substitution method were generally comparable in bias and rMSE when estimating the AM and GM. For the GSD and the 95th percentile, the Bayesian method with non-informative priors was more biased and had a higher rMSE than the β-substitution method, but use of more informative priors generally improved the Bayesian method's performance, making both the bias and the rMSE more comparable to the β-substitution method. An advantage of the Bayesian method is that it provided estimates of uncertainty for these parameters of interest and good coverage, whereas the β-substitution method only provided estimates of uncertainty for the AM, and coverage was not as consistent. Selection of one or the other method depends on the needs of the practitioner, the availability of prior information, and the distribution characteristics of the measurement data. We suggest the use of Bayesian methods if the practitioner has the

Kinematic Distances: A Monte Carlo Method

NASA Astrophysics Data System (ADS)

Wenger, Trey V.; Balser, Dana S.; Anderson, L. D.; Bania, T. M.

2018-03-01

Distances to high-mass star-forming regions (HMSFRs) in the Milky Way are a crucial constraint on the structure of the Galaxy. Only kinematic distances are available for a majority of the HMSFRs in the Milky Way. Here, we compare the kinematic and parallax distances of 75 Galactic HMSFRs to assess the accuracy of kinematic distances. We derive the kinematic distances using three different methods: the traditional method using the Brand & Blitz rotation curve (Method A), the traditional method using the Reid et al. rotation curve and updated solar motion parameters (Method B), and a Monte Carlo technique (Method C). Methods B and C produce kinematic distances closest to the parallax distances, with median differences of 13% (0.43 {kpc}) and 17% (0.42 {kpc}), respectively. Except in the vicinity of the tangent point, the kinematic distance uncertainties derived by Method C are smaller than those of Methods A and B. In a large region of the Galaxy, the Method C kinematic distances constrain both the distances and the Galactocentric positions of HMSFRs more accurately than parallax distances. Beyond the tangent point along ℓ = 30°, for example, the Method C kinematic distance uncertainties reach a minimum of 10% of the parallax distance uncertainty at a distance of 14 {kpc}. We develop a prescription for deriving and applying the Method C kinematic distances and distance uncertainties. The code to generate the Method C kinematic distances is publicly available and may be utilized through an online tool.

Multiscale Methods for Nuclear Reactor Analysis

NASA Astrophysics Data System (ADS)

Collins, Benjamin S.

The ability to accurately predict local pin powers in nuclear reactors is necessary to understand the mechanisms that cause fuel pin failure during steady state and transient operation. In the research presented here, methods are developed to improve the local solution using high order methods with boundary conditions from a low order global solution. Several different core configurations were tested to determine the improvement in the local pin powers compared to the standard techniques, that use diffusion theory and pin power reconstruction (PPR). Two different multiscale methods were developed and analyzed; the post-refinement multiscale method and the embedded multiscale method. The post-refinement multiscale methods use the global solution to determine boundary conditions for the local solution. The local solution is solved using either a fixed boundary source or an albedo boundary condition; this solution is "post-refinement" and thus has no impact on the global solution. The embedded multiscale method allows the local solver to change the global solution to provide an improved global and local solution. The post-refinement multiscale method is assessed using three core designs. When the local solution has more energy groups, the fixed source method has some difficulties near the interface: however the albedo method works well for all cases. In order to remedy the issue with boundary condition errors for the fixed source method, a buffer region is used to act as a filter, which decreases the sensitivity of the solution to the boundary condition. Both the albedo and fixed source methods benefit from the use of a buffer region. Unlike the post-refinement method, the embedded multiscale method alters the global solution. The ability to change the global solution allows for refinement in areas where the errors in the few group nodal diffusion are typically large. The embedded method is shown to improve the global solution when it is applied to a MOX/LEU assembly

Maps and navigation methods

NASA Technical Reports Server (NTRS)

Duval, A

1922-01-01

Different maps and scales are discussed with particular emphasis on their use in aviation. The author makes the observation that current navigation methods are slow and dangerous and should be replaced by scientific methods of navigation based on loxodromy and the use of the compass.

The Oxygen Flask Method

ERIC Educational Resources Information Center

Boulton, L. H.

1973-01-01

Discusses application of Schoniger's method of quantitative organic elemental analysis in teaching of qualitative analysis of the halogens, nitrogen, sulphur, and phosphorus. Indicates that the oxygen flask method is safe and suitable for both high school and college courses because of simple apparatus requirements. (CC)

Research Methods in Education

ERIC Educational Resources Information Center

Check, Joseph; Schutt, Russell K.

2011-01-01

"Research Methods in Education" introduces research methods as an integrated set of techniques for investigating questions about the educational world. This lively, innovative text helps students connect technique and substance, appreciate the value of both qualitative and quantitative methodologies, and make ethical research decisions.…

Accuracy evaluation of dental models manufactured by CAD/CAM milling method and 3D printing method.

PubMed

Jeong, Yoo-Geum; Lee, Wan-Sun; Lee, Kyu-Bok

2018-06-01

To evaluate the accuracy of a model made using the computer-aided design/computer-aided manufacture (CAD/CAM) milling method and 3D printing method and to confirm its applicability as a work model for dental prosthesis production. First, a natural tooth model (ANA-4, Frasaco, Germany) was scanned using an oral scanner. The obtained scan data were then used as a CAD reference model (CRM), to produce a total of 10 models each, either using the milling method or the 3D printing method. The 20 models were then scanned using a desktop scanner and the CAD test model was formed. The accuracy of the two groups was compared using dedicated software to calculate the root mean square (RMS) value after superimposing CRM and CAD test model (CTM). The RMS value (152±52 µm) of the model manufactured by the milling method was significantly higher than the RMS value (52±9 µm) of the model produced by the 3D printing method. The accuracy of the 3D printing method is superior to that of the milling method, but at present, both methods are limited in their application as a work model for prosthesis manufacture.

Method for fusing bone

DOEpatents

Mourant, Judith R.; Anderson, Gerhard D.; Bigio, Irving J.; Johnson, Tamara M.

1996-01-01

Method for fusing bone. The present invention is a method for joining hard tissue which includes chemically removing the mineral matrix from a thin layer of the surfaces to be joined, placing the two bones together, and heating the joint using electromagnetic radiation. The goal of the method is not to produce a full-strength weld of, for example, a cortical bone of the tibia, but rather to produce a weld of sufficient strength to hold the bone halves in registration while either external fixative devices are applied to stabilize the bone segments, or normal healing processes restore full strength to the tibia.

Spectral methods on arbitrary grids

NASA Technical Reports Server (NTRS)

Carpenter, Mark H.; Gottlieb, David

1995-01-01

Stable and spectrally accurate numerical methods are constructed on arbitrary grids for partial differential equations. These new methods are equivalent to conventional spectral methods but do not rely on specific grid distributions. Specifically, we show how to implement Legendre Galerkin, Legendre collocation, and Laguerre Galerkin methodology on arbitrary grids.

Methods for Neutron Spectrometry

DOE R&D Accomplishments Database

Brockhouse, Bertram N.

1961-01-09

The appropriate theories and the general philosophy of methods of measurement and treatment of data neutron spectrometry are discussed. Methods of analysis of results for liquids using the Van Hove formulation, and for crystals using the Born-von Karman theory, are reviewed. The most useful of the available methods of measurement are considered to be the crystal spectrometer methods and the pulsed monoenergetic beam/time-of-flight method. Pulsed-beam spectrometers have the advantage of higher counting rates than crystal spectrometers, especially in view of the fact that simultaneous measurements in several counters at different angles of scattering are possible in pulsed-beam spectrometers. The crystal spectrometer permits several valuable new types of specialized experiments to be performed, especially energy distribution measurements at constant momentum transfer. The Chalk River triple-axis crystal-spectrometer is discussed, with reference to its use in making the specialized experiments. The Chalk River rotating crystal (pulsed-beam) spectrometer is described, and a comparison of this type instrument with other pulsed-beam spectrometers is made. A partial outline of the theory of operation of rotating-crystal spectrometers is presented. The use of quartz-crystal filters for fast neutron elimination and for order elimination is discussed. (auth)

Two Project Methods: Preliminary Observations on the Similarities and Differences between William Heard Kilpatrick's Project Method and John Dewey's Problem-Solving Method

ERIC Educational Resources Information Center

Sutinen, Ari

2013-01-01

The project method became a famous teaching method when William Heard Kilpatrick published his article "Project Method" in 1918. The key idea in Kilpatrick's project method is to try to explain how pupils learn things when they work in projects toward different common objects. The same idea of pupils learning by work or action in an…

An introduction to g methods.

PubMed

Naimi, Ashley I; Cole, Stephen R; Kennedy, Edward H

2017-04-01

Robins' generalized methods (g methods) provide consistent estimates of contrasts (e.g. differences, ratios) of potential outcomes under a less restrictive set of identification conditions than do standard regression methods (e.g. linear, logistic, Cox regression). Uptake of g methods by epidemiologists has been hampered by limitations in understanding both conceptual and technical details. We present a simple worked example that illustrates basic concepts, while minimizing technical complications. © The Author 2016; all rights reserved. Published by Oxford University Press on behalf of the International Epidemiological Association.

Text-in-Context: A Method for Extracting Findings in Mixed-Methods Mixed Research Synthesis Studies

PubMed Central

Leeman, Jennifer; Knafl, Kathleen; Crandell, Jamie L.

2012-01-01

Aim Our purpose in this paper is to propose a new method for extracting findings from research reports included in mixed-methods mixed research synthesis studies. Background International initiatives in the domains of systematic review and evidence synthesis have been focused on broadening the conceptualization of evidence, increased methodological inclusiveness and the production of evidence syntheses that will be accessible to and usable by a wider range of consumers. Initiatives in the general mixed-methods research field have been focused on developing truly integrative approaches to data analysis and interpretation. Data source The data extraction challenges described here were encountered and the method proposed for addressing these challenges was developed, in the first year of the ongoing (2011–2016) study: Mixed-Methods Synthesis of Research on Childhood Chronic Conditions and Family. Discussion To preserve the text-in-context of findings in research reports, we describe a method whereby findings are transformed into portable statements that anchor results to relevant information about sample, source of information, time, comparative reference point, magnitude and significance and study-specific conceptions of phenomena. Implications for nursing The data extraction method featured here was developed specifically to accommodate mixed-methods mixed research synthesis studies conducted in nursing and other health sciences, but reviewers might find it useful in other kinds of research synthesis studies. Conclusion This data extraction method itself constitutes a type of integration to preserve the methodological context of findings when statements are read individually and in comparison to each other. PMID:22924808

Alternate Methods of Teaching Psychopharmacology

ERIC Educational Resources Information Center

Zisook, Sidney; Benjamin, Sheldon; Balon, Richard; Glick, Ira; Louie, Alan; Moutier, Christine; Moyer, Trenton; Santos, Cynthia; Servis, Mark

2005-01-01

Objective: This article reviews methods used to teach psychopharmacology to psychiatry residents that utilize principles of adult learning, enlist active participation of residents, and provide faculty with skills to seek, analyze, and use new information over the course of their careers. Methods: The pros and cons of five "nonlecture" methods of…

Methods for Bacteriophage Preservation.

PubMed

Łobocka, Małgorzata B; Głowacka, Aleksandra; Golec, Piotr

2018-01-01

In a view of growing interest in bacteriophages as the most abundant members of microbial communities and as antibacterial agents, reliable methods for bacteriophage long-term preservation, that warrant the access to original or mutant stocks of unchanged properties, have become of crucial importance. A storage method that retains the infectivity of any kind of bacteriophage virions, either in a cell lysate or in a purified suspension, does not exist, due to the enormous diversity of bacteriophages and hence the differentiation of their sensitivity to various storage conditions. Here, we describe a method of long-term bacteriophage preservation, which is based on freezing of freshly infected susceptible bacteria at early stages of bacteriophage development. The infected bacteria release mature bacteriophages upon melting enabling the recovery of bacteriophage virions with high efficiency. The only limitation of this method is the sensitivity of bacteriophage host to deep-freezing, and thus it can be used for the long-term preservation of the vast majority of bacteriophages.

[Comparison of two algorithms for development of design space-overlapping method and probability-based method].

PubMed

Shao, Jing-Yuan; Qu, Hai-Bin; Gong, Xing-Chu

2018-05-01

In this work, two algorithms (overlapping method and the probability-based method) for design space calculation were compared by using the data collected from extraction process of Codonopsis Radix as an example. In the probability-based method, experimental error was simulated to calculate the probability of reaching the standard. The effects of several parameters on the calculated design space were studied, including simulation number, step length, and the acceptable probability threshold. For the extraction process of Codonopsis Radix, 10 000 times of simulation and 0.02 for the calculation step length can lead to a satisfactory design space. In general, the overlapping method is easy to understand, and can be realized by several kinds of commercial software without coding programs, but the reliability of the process evaluation indexes when operating in the design space is not indicated. Probability-based method is complex in calculation, but can provide the reliability to ensure that the process indexes can reach the standard within the acceptable probability threshold. In addition, there is no probability mutation in the edge of design space by probability-based method. Therefore, probability-based method is recommended for design space calculation. Copyright© by the Chinese Pharmaceutical Association.

Analysis of optimisation method for a two-stroke piston ring using the Finite Element Method and the Simulated Annealing Method

NASA Astrophysics Data System (ADS)

Kaliszewski, M.; Mazuro, P.

2016-09-01

Simulated Annealing Method of optimisation for the sealing piston ring geometry is tested. The aim of optimisation is to develop ring geometry which would exert demanded pressure on a cylinder just while being bended to fit the cylinder. Method of FEM analysis of an arbitrary piston ring geometry is applied in an ANSYS software. The demanded pressure function (basing on formulae presented by A. Iskra) as well as objective function are introduced. Geometry definition constructed by polynomials in radial coordinate system is delivered and discussed. Possible application of Simulated Annealing Method in a piston ring optimisation task is proposed and visualised. Difficulties leading to possible lack of convergence of optimisation are presented. An example of an unsuccessful optimisation performed in APDL is discussed. Possible line of further optimisation improvement is proposed.

Comparison of two Galerkin quadrature methods

DOE PAGES

Morel, Jim E.; Warsa, James; Franke, Brian C.; ...

2017-02-21

Here, we compare two methods for generating Galerkin quadratures. In method 1, the standard S N method is used to generate the moment-to-discrete matrix and the discrete-to-moment matrix is generated by inverting the moment-to-discrete matrix. This is a particular form of the original Galerkin quadrature method. In method 2, which we introduce here, the standard S N method is used to generate the discrete-to-moment matrix and the moment-to-discrete matrix is generated by inverting the discrete-to-moment matrix. With an N-point quadrature, method 1 has the advantage that it preserves N eigenvalues and N eigenvectors of the scattering operator in a pointwisemore » sense. With an N-point quadrature, method 2 has the advantage that it generates consistent angular moment equations from the corresponding S N equations while preserving N eigenvalues of the scattering operator. Our computational results indicate that these two methods are quite comparable for the test problem considered.« less

Comparison of two Galerkin quadrature methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morel, Jim E.; Warsa, James; Franke, Brian C.

Here, we compare two methods for generating Galerkin quadratures. In method 1, the standard S N method is used to generate the moment-to-discrete matrix and the discrete-to-moment matrix is generated by inverting the moment-to-discrete matrix. This is a particular form of the original Galerkin quadrature method. In method 2, which we introduce here, the standard S N method is used to generate the discrete-to-moment matrix and the moment-to-discrete matrix is generated by inverting the discrete-to-moment matrix. With an N-point quadrature, method 1 has the advantage that it preserves N eigenvalues and N eigenvectors of the scattering operator in a pointwisemore » sense. With an N-point quadrature, method 2 has the advantage that it generates consistent angular moment equations from the corresponding S N equations while preserving N eigenvalues of the scattering operator. Our computational results indicate that these two methods are quite comparable for the test problem considered.« less

A typology of health marketing research methods--combining public relations methods with organizational concern.

PubMed

Rotarius, Timothy; Wan, Thomas T H; Liberman, Aaron

2007-01-01

Research plays a critical role throughout virtually every conduit of the health services industry. The key terms of research, public relations, and organizational interests are discussed. Combining public relations as a strategic methodology with the organizational concern as a factor, a typology of four different research methods emerges. These four health marketing research methods are: investigative, strategic, informative, and verification. The implications of these distinct and contrasting research methods are examined.

Contaminant treatment method

DOEpatents

Shapiro, Andrew Philip; Thornton, Roy Fred; Salvo, Joseph James

2003-01-01

The present invention provides a method for treating contaminated media. The method comprises introducing remediating ions consisting essentially of ferrous ions, and being peroxide-free, in the contaminated media; applying a potential difference across the contaminated media to cause the remediating ions to migrate into contact with contaminants in the contaminated media; chemically degrading contaminants in the contaminated media by contact with the remediating ions; monitoring the contaminated media for degradation products of the contaminants; and controlling the step of applying the potential difference across the contaminated media in response to the step of monitoring.

76 FR 28664 - Method 301-Field Validation of Pollutant Measurement Methods From Various Waste Media

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-18

... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 63 [OAR-2004-0080, FRL-9306-8] RIN 2060-AF00 Method 301--Field Validation of Pollutant Measurement Methods From Various Waste Media AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: This action amends EPA's Method 301, Field Validation...

Comparison of a discrete steepest ascent method with the continuous steepest ascent method for optimal programing

NASA Technical Reports Server (NTRS)

Childs, A. G.

1971-01-01

A discrete steepest ascent method which allows controls which are not piecewise constant (for example, it allows all continuous piecewise linear controls) was derived for the solution of optimal programming problems. This method is based on the continuous steepest ascent method of Bryson and Denham and new concepts introduced by Kelley and Denham in their development of compatible adjoints for taking into account the effects of numerical integration. The method is a generalization of the algorithm suggested by Canon, Cullum, and Polak with the details of the gradient computation given. The discrete method was compared with the continuous method for an aerodynamics problem for which an analytic solution is given by Pontryagin's maximum principle, and numerical results are presented. The discrete method converges more rapidly than the continuous method at first, but then for some undetermined reason, loses its exponential convergence rate. A comparsion was also made for the algorithm of Canon, Cullum, and Polak using piecewise constant controls. This algorithm is very competitive with the continuous algorithm.

Methods of making textured catalysts

DOEpatents

Werpy, Todd [West Richland, WA; Frye, Jr., John G.; Wang, Yong [Richland, WA; Zacher, Alan H [Kennewick, WA

2010-08-17

A textured catalyst having a hydrothermally-stable support, a metal oxide and a catalyst component is described. Methods of conducting aqueous phase reactions that are catalyzed by a textured catalyst are also described. The invention also provides methods of making textured catalysts and methods of making chemical products using a textured catalyst.

The Discovery Method in Training.

ERIC Educational Resources Information Center

Belbin, R. M.

In the form of a discussion between faceless people, this booklet concerns discovery learning and its advantages. Subjects covered in the discussions are: Introducing the Discovery Method; An Experiment with British Railways; The OECD Research Projects in U.S.A., Austria, and Sweden; How the Discovery Method Differs from Other Methods; Discovery…

Nano-ceramics and method thereof

DOEpatents

Satcher, Jr., Joe H.; Gash, Alex [Livermore, CA; Simpson, Randall [Livermore, CA; Landingham, Richard [Livermore, CA; Reibold, Robert A [Salida, CA

2006-08-08

Disclosed herein is a method to produce ceramic materials utilizing the sol-gel process. The methods enable the preparation of intimate homogeneous dispersions of materials while offering the ability to control the size of one component within another. The method also enables the preparation of materials that will densify at reduced temperature.

The Method of Curvatures.

ERIC Educational Resources Information Center

Greenslade, Thomas B., Jr.; Miller, Franklin, Jr.

1981-01-01

Describes method for locating images in simple and complex systems of thin lenses and spherical mirrors. The method helps students to understand differences between real and virtual images. It is helpful in discussing the human eye and the correction of imperfect vision by the use of glasses. (Author/SK)

WWW: The Scientific Method

ERIC Educational Resources Information Center

Blystone, Robert V.; Blodgett, Kevin

2006-01-01

The scientific method is the principal methodology by which biological knowledge is gained and disseminated. As fundamental as the scientific method may be, its historical development is poorly understood, its definition is variable, and its deployment is uneven. Scientific progress may occur without the strictures imposed by the formal…

Sampling system and method

DOEpatents

Decker, David L; Lyles, Brad F; Purcell, Richard G; Hershey, Ronald Lee

2014-05-20

An apparatus and method for supporting a tubing bundle during installation or removal. The apparatus includes a clamp for securing the tubing bundle to an external wireline. The method includes deploying the tubing bundle and wireline together, The tubing bundle is periodically secured to the wireline using a clamp.

A Comparison of the β-Substitution Method and a Bayesian Method for Analyzing Left-Censored Data

PubMed Central

Huynh, Tran; Quick, Harrison; Ramachandran, Gurumurthy; Banerjee, Sudipto; Stenzel, Mark; Sandler, Dale P.; Engel, Lawrence S.; Kwok, Richard K.; Blair, Aaron; Stewart, Patricia A.

2016-01-01

Classical statistical methods for analyzing exposure data with values below the detection limits are well described in the occupational hygiene literature, but an evaluation of a Bayesian approach for handling such data is currently lacking. Here, we first describe a Bayesian framework for analyzing censored data. We then present the results of a simulation study conducted to compare the β-substitution method with a Bayesian method for exposure datasets drawn from lognormal distributions and mixed lognormal distributions with varying sample sizes, geometric standard deviations (GSDs), and censoring for single and multiple limits of detection. For each set of factors, estimates for the arithmetic mean (AM), geometric mean, GSD, and the 95th percentile (X0.95) of the exposure distribution were obtained. We evaluated the performance of each method using relative bias, the root mean squared error (rMSE), and coverage (the proportion of the computed 95% uncertainty intervals containing the true value). The Bayesian method using non-informative priors and the β-substitution method were generally comparable in bias and rMSE when estimating the AM and GM. For the GSD and the 95th percentile, the Bayesian method with non-informative priors was more biased and had a higher rMSE than the β-substitution method, but use of more informative priors generally improved the Bayesian method’s performance, making both the bias and the rMSE more comparable to the β-substitution method. An advantage of the Bayesian method is that it provided estimates of uncertainty for these parameters of interest and good coverage, whereas the β-substitution method only provided estimates of uncertainty for the AM, and coverage was not as consistent. Selection of one or the other method depends on the needs of the practitioner, the availability of prior information, and the distribution characteristics of the measurement data. We suggest the use of Bayesian methods if the practitioner has the

Drinking water test methods in crisis-afflicted areas: comparison of methods under field conditions.

PubMed

Merle, Roswitha; Bleul, Ingo; Schulenburg, Jörg; Kreienbrock, Lothar; Klein, Günter

2011-11-01

To simplify the testing of drinking water in crisis-afflicted areas (as in Kosovo in 2007), rapid test methods were compared with the standard test. For Escherichia coli and coliform pathogens, rapid tests were made available: Colilert(®)-18, P/A test with 4-methylumbelliferyl-β-D-glucoronid, and m-Endo Broth. Biochemical differentiation was carried out by Enterotube™ II. Enterococci were determined following the standard ISO test and by means of Enterolert™. Four hundred ninety-nine water samples were tested for E. coli and coliforms using four methods. Following the standard method, 20.8% (n=104) of the samples contained E. coli, whereas the rapid tests detected between 19.6% (m-Endo Broth, 92.0% concordance) and 20.0% (concordance: 93.6% Colilert-18 and 94.8% P/A-test) positive samples. Regarding coliforms, the percentage of concordant results ranged from 98.4% (P/A-test) to 99.0% (Colilert-18). Colilert-18 and m-Endo Broth detected even more positive samples than the standard method did. Enterococci were detected in 93 of 573 samples by the standard method, but in 92 samples by Enterolert (concordance: 99.5%). Considering the high-quality equipment and time requirements of the standard method, the use of rapid tests in crisis-afflicted areas is sufficiently reliable.

Chemical control methods and tools

Treesearch

Steven Manning; James Miller

2011-01-01

After determining the best course of action for control of an invasive plant population, it is important to understand the variety of methods available to the integrated pest management professional. A variety of methods are now widely used in managing invasive plants in natural areas, including chemical, mechanical, and cultural control methods. Once the preferred...

Linguistic Method: Yesterday and Today.

ERIC Educational Resources Information Center

Rauch, Irmengard

This paper introduces the reader to a brief history of the focus of linguistic method from prehistoric times, through the Classical era, the Middle Ages, to the present. The scientific orientation of linguistic method is exploited; a set of specific principles is found to unify most of today's diverse methods. The success of linguistics is…

Generational differences of baccalaureate nursing students' preferred teaching methods and faculty use of teaching methods

NASA Astrophysics Data System (ADS)

Delahoyde, Theresa

Nursing education is experiencing a generational phenomenon with student enrollment spanning three generations. Classrooms of the 21st century include the occasional Baby Boomer and a large number of Generation X and Generation Y students. Each of these generations has its own unique set of characteristics that have been shaped by values, trends, behaviors, and events in society. These generational characteristics create vast opportunities to learn, as well as challenges. One such challenge is the use of teaching methods that are congruent with nursing student preferences. Although there is a wide range of studies conducted on student learning styles within the nursing education field, there is little research on the preferred teaching methods of nursing students. The purpose of this quantitative, descriptive study was to compare the preferred teaching methods of multi-generational baccalaureate nursing students with faculty use of teaching methods. The research study included 367 participants; 38 nursing faculty and 329 nursing students from five different colleges within the Midwest region. The results of the two-tailed t-test found four statistically significant findings between Generation X and Y students and their preferred teaching methods including; lecture, listening to the professor lecture versus working in groups; actively participating in group discussion; and the importance of participating in group assignments. The results of the Analysis of Variance (ANOVA) found seventeen statistically significant findings between levels of students (freshmen/sophomores, juniors, & seniors) and their preferred teaching methods. Lecture was found to be the most frequently used teaching method by faculty as well as the most preferred teaching method by students. Overall, the support for a variety of teaching methods was also found in the analysis of data.

Discussion summary: Fictitious domain methods

NASA Technical Reports Server (NTRS)

Glowinski, Rowland; Rodrigue, Garry

1991-01-01

Fictitious Domain methods are constructed in the following manner: Suppose a partial differential equation is to be solved on an open bounded set, Omega, in 2-D or 3-D. Let R be a rectangle domain containing the closure of Omega. The partial differential equation is first solved on R. Using the solution on R, the solution of the equation on Omega is then recovered by some procedure. The advantage of the fictitious domain method is that in many cases the solution of a partial differential equation on a rectangular region is easier to compute than on a nonrectangular region. Fictitious domain methods for solving elliptic PDEs on general regions are also very efficient when used on a parallel computer. The reason is that one can use the many domain decomposition methods that are available for solving the PDE on the fictitious rectangular region. The discussion on fictitious domain methods began with a talk by R. Glowinski in which he gave some examples of a variational approach to ficititious domain methods for solving the Helmholtz and Navier-Stokes equations.

Methods for Quantitative Creatinine Determination.

PubMed

Moore, John F; Sharer, J Daniel

2017-04-06

Reliable measurement of creatinine is necessary to assess kidney function, and also to quantitate drug levels and diagnostic compounds in urine samples. The most commonly used methods are based on the Jaffe principal of alkaline creatinine-picric acid complex color formation. However, other compounds commonly found in serum and urine may interfere with Jaffe creatinine measurements. Therefore, many laboratories have made modifications to the basic method to remove or account for these interfering substances. This appendix will summarize the basic Jaffe method, as well as a modified, automated version. Also described is a high performance liquid chromatography (HPLC) method that separates creatinine from contaminants prior to direct quantification by UV absorption. Lastly, a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method is described that uses stable isotope dilution to reliably quantify creatinine in any sample. This last approach has been recommended by experts in the field as a means to standardize all quantitative creatinine methods against an accepted reference. © 2017 by John Wiley & Sons, Inc. Copyright © 2017 John Wiley & Sons, Inc.

Astronomical Methods in Aerial Navigation

NASA Technical Reports Server (NTRS)

Beij, K Hilding

1925-01-01

The astronomical method of determining position is universally used in marine navigation and may also be of service in aerial navigation. The practical application of the method, however, must be modified and adapted to conform to the requirements of aviation. Much of this work of adaptation has already been accomplished, but being scattered through various technical journals in a number of languages, is not readily available. This report is for the purpose of collecting under one cover such previous work as appears to be of value to the aerial navigator, comparing instruments and methods, indicating the best practice, and suggesting future developments. The various methods of determining position and their application and value are outlined, and a brief resume of the theory of the astronomical method is given. Observation instruments are described in detail. A complete discussion of the reduction of observations follows, including a rapid method of finding position from the altitudes of two stars. Maps and map cases are briefly considered. A bibliography of the subject is appended.

Methods of verifying net carbon

DOE Office of Scientific and Technical Information (OSTI.GOV)

McClung, M.

1996-10-01

Problems currently exist with using net carbon as an industrial standard to gauge smelter performance. First, throughout the industry there are a number of different methods used for determining net carbon. Also, until recently there has not been a viable method to cross check or predict change in net carbon. This inherently leads to differences and most likely inaccuracies when comparing performances of different plants using a net carbon number. Ravenswood uses specific methods when calculating the net carbon balance. The R and D Carbon, Ltd. formula developed by Verner Fisher, et al, to predict and cross check net carbonmore » based on baked carbon core analysis has been successfully used. Another method is used, as a cross check, which is based on the raw materials (cokes and pitch) usage as related to the metal produced. The combination of these methods gives a definitive representation of the carbon performance in the reduction cell. This report details the methods Ravenswood Aluminum uses and the information derived from it.« less

DNA-based methods of geochemical prospecting

DOEpatents

Ashby, Matthew [Mill Valley, CA

2011-12-06

The present invention relates to methods for performing surveys of the genetic diversity of a population. The invention also relates to methods for performing genetic analyses of a population. The invention further relates to methods for the creation of databases comprising the survey information and the databases created by these methods. The invention also relates to methods for analyzing the information to correlate the presence of nucleic acid markers with desired parameters in a sample. These methods have application in the fields of geochemical exploration, agriculture, bioremediation, environmental analysis, clinical microbiology, forensic science and medicine.

Introduction to multigrid methods

NASA Technical Reports Server (NTRS)

Wesseling, P.

1995-01-01

These notes were written for an introductory course on the application of multigrid methods to elliptic and hyperbolic partial differential equations for engineers, physicists and applied mathematicians. The use of more advanced mathematical tools, such as functional analysis, is avoided. The course is intended to be accessible to a wide audience of users of computational methods. We restrict ourselves to finite volume and finite difference discretization. The basic principles are given. Smoothing methods and Fourier smoothing analysis are reviewed. The fundamental multigrid algorithm is studied. The smoothing and coarse grid approximation properties are discussed. Multigrid schedules and structured programming of multigrid algorithms are treated. Robustness and efficiency are considered.

Mixed-Methods Research Methodologies

ERIC Educational Resources Information Center

Terrell, Steven R.

2012-01-01

Mixed-Method studies have emerged from the paradigm wars between qualitative and quantitative research approaches to become a widely used mode of inquiry. Depending on choices made across four dimensions, mixed-methods can provide an investigator with many design choices which involve a range of sequential and concurrent strategies. Defining…

Mixed Methods Research in School Psychology: A Mixed Methods Investigation of Trends in the Literature

ERIC Educational Resources Information Center

Powell, Heather; Mihalas, Stephanie; Onwuegbuzie, Anthony J.; Suldo, Shannon; Daley, Christine E.

2008-01-01

This article illustrates the utility of mixed methods research (i.e., combining quantitative and qualitative techniques) to the field of school psychology. First, the use of mixed methods approaches in school psychology practice is discussed. Second, the mixed methods research process is described in terms of school psychology research. Third, the…

Life cycle management of analytical methods.

PubMed

Parr, Maria Kristina; Schmidt, Alexander H

2018-01-05

In modern process management, the life cycle concept gains more and more importance. It focusses on the total costs of the process from invest to operation and finally retirement. Also for analytical procedures an increasing interest for this concept exists in the recent years. The life cycle of an analytical method consists of design, development, validation (including instrumental qualification, continuous method performance verification and method transfer) and finally retirement of the method. It appears, that also regulatory bodies have increased their awareness on life cycle management for analytical methods. Thus, the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH), as well as the United States Pharmacopeial Forum discuss the enrollment of new guidelines that include life cycle management of analytical methods. The US Pharmacopeia (USP) Validation and Verification expert panel already proposed a new General Chapter 〈1220〉 "The Analytical Procedure Lifecycle" for integration into USP. Furthermore, also in the non-regulated environment a growing interest on life cycle management is seen. Quality-by-design based method development results in increased method robustness. Thereby a decreased effort is needed for method performance verification, and post-approval changes as well as minimized risk of method related out-of-specification results. This strongly contributes to reduced costs of the method during its life cycle. Copyright © 2017 Elsevier B.V. All rights reserved.

Comparison of the convolution quadrature method and enhanced inverse FFT with application in elastodynamic boundary element method

NASA Astrophysics Data System (ADS)

Schanz, Martin; Ye, Wenjing; Xiao, Jinyou

2016-04-01

Transient problems can often be solved with transformation methods, where the inverse transformation is usually performed numerically. Here, the discrete Fourier transform in combination with the exponential window method is compared with the convolution quadrature method formulated as inverse transformation. Both are inverse Laplace transforms, which are formally identical but use different complex frequencies. A numerical study is performed, first with simple convolution integrals and, second, with a boundary element method (BEM) for elastodynamics. Essentially, when combined with the BEM, the discrete Fourier transform needs less frequency calculations, but finer mesh compared to the convolution quadrature method to obtain the same level of accuracy. If further fast methods like the fast multipole method are used to accelerate the boundary element method the convolution quadrature method is better, because the iterative solver needs much less iterations to converge. This is caused by the larger real part of the complex frequencies necessary for the calculation, which improves the conditions of system matrix.

Collocation and Galerkin Time-Stepping Methods

NASA Technical Reports Server (NTRS)

Huynh, H. T.

2011-01-01

We study the numerical solutions of ordinary differential equations by one-step methods where the solution at tn is known and that at t(sub n+1) is to be calculated. The approaches employed are collocation, continuous Galerkin (CG) and discontinuous Galerkin (DG). Relations among these three approaches are established. A quadrature formula using s evaluation points is employed for the Galerkin formulations. We show that with such a quadrature, the CG method is identical to the collocation method using quadrature points as collocation points. Furthermore, if the quadrature formula is the right Radau one (including t(sub n+1)), then the DG and CG methods also become identical, and they reduce to the Radau IIA collocation method. In addition, we present a generalization of DG that yields a method identical to CG and collocation with arbitrary collocation points. Thus, the collocation, CG, and generalized DG methods are equivalent, and the latter two methods can be formulated using the differential instead of integral equation. Finally, all schemes discussed can be cast as s-stage implicit Runge-Kutta methods.

Method for protein structure alignment

DOEpatents

Blankenbecler, Richard; Ohlsson, Mattias; Peterson, Carsten; Ringner, Markus

2005-02-22

This invention provides a method for protein structure alignment. More particularly, the present invention provides a method for identification, classification and prediction of protein structures. The present invention involves two key ingredients. First, an energy or cost function formulation of the problem simultaneously in terms of binary (Potts) assignment variables and real-valued atomic coordinates. Second, a minimization of the energy or cost function by an iterative method, where in each iteration (1) a mean field method is employed for the assignment variables and (2) exact rotation and/or translation of atomic coordinates is performed, weighted with the corresponding assignment variables.

Method for producing redox shuttles

DOEpatents

Pupek, Krzysztof Z.; Dzwiniel, Trevor L.; Krumdick, Gregory K.

2015-03-03

A single step method for producing a redox shuttle having the formula 2,5-di-tert-butyl-1,4-phenylene tetraethyl bis(phosphate) is provided, the method comprising phosphorylating tert butyl hydroquinone with a phosphate-containing reagent. Also provided is method for producing 2,5-di-tert-butyl-1,4-phenylene tetraethyl bis(phosphate), the method comprising solubilizing tert-butyl hydroquinone and tetrabutylammonium bromide with methyltetrahydrofuran to create a mixture; heating the mixture while adding base to the mixture in an amount to turn the mixture orange; and adding diethyl chlorophosphate to the orange mixture in an amount to phosphorylate the hydroquinone.

METHOD 544. DETERMINATION OF MICROCYSTINS AND ...

EPA Pesticide Factsheets

Method 544 is an accurate and precise analytical method to determine six microcystins (including MC-LR) and nodularin in drinking water using solid phase extraction and liquid chromatography tandem mass spectrometry (SPE-LC/MS/MS). The advantage of this SPE-LC/MS/MS is its sensitivity and ability to speciate the microcystins. This method development task establishes sample preservation techniques, sample concentration and analytical procedures, aqueous and extract holding time criteria and quality control procedures. Draft Method 544 undergone a multi-laboratory verification to ensure other laboratories can implement the method and achieve the quality control measures specified in the method. It is anticipated that Method 544 may be used in UCMR 4 to collect nationwide occurrence data for selected microcystins in drinking water. The purpose of this research project is to develop an accurate and precise analytical method to concentrate and determine selected MCs and nodularin in drinking water.

The Views of Turkish Pre-Service Teachers about Effectiveness of Cluster Method as a Teaching Writing Method

ERIC Educational Resources Information Center

Kitis, Emine; Türkel, Ali

2017-01-01

The aim of this study is to find out Turkish pre-service teachers' views on effectiveness of cluster method as a writing teaching method. The Cluster Method can be defined as a connotative creative writing method. The way the method works is that the person who brainstorms on connotations of a word or a concept in abscence of any kind of…

A point cloud modeling method based on geometric constraints mixing the robust least squares method

NASA Astrophysics Data System (ADS)

Yue, JIanping; Pan, Yi; Yue, Shun; Liu, Dapeng; Liu, Bin; Huang, Nan

2016-10-01

The appearance of 3D laser scanning technology has provided a new method for the acquisition of spatial 3D information. It has been widely used in the field of Surveying and Mapping Engineering with the characteristics of automatic and high precision. 3D laser scanning data processing process mainly includes the external laser data acquisition, the internal industry laser data splicing, the late 3D modeling and data integration system. For the point cloud modeling, domestic and foreign researchers have done a lot of research. Surface reconstruction technology mainly include the point shape, the triangle model, the triangle Bezier surface model, the rectangular surface model and so on, and the neural network and the Alfa shape are also used in the curved surface reconstruction. But in these methods, it is often focused on single surface fitting, automatic or manual block fitting, which ignores the model's integrity. It leads to a serious problems in the model after stitching, that is, the surfaces fitting separately is often not satisfied with the well-known geometric constraints, such as parallel, vertical, a fixed angle, or a fixed distance. However, the research on the special modeling theory such as the dimension constraint and the position constraint is not used widely. One of the traditional modeling methods adding geometric constraints is a method combing the penalty function method and the Levenberg-Marquardt algorithm (L-M algorithm), whose stability is pretty good. But in the research process, it is found that the method is greatly influenced by the initial value. In this paper, we propose an improved method of point cloud model taking into account the geometric constraint. We first apply robust least-squares to enhance the initial value's accuracy, and then use penalty function method to transform constrained optimization problems into unconstrained optimization problems, and finally solve the problems using the L-M algorithm. The experimental results

PDEs on moving surfaces via the closest point method and a modified grid based particle method

NASA Astrophysics Data System (ADS)

Petras, A.; Ruuth, S. J.

2016-05-01

Partial differential equations (PDEs) on surfaces arise in a wide range of applications. The closest point method (Ruuth and Merriman (2008) [20]) is a recent embedding method that has been used to solve a variety of PDEs on smooth surfaces using a closest point representation of the surface and standard Cartesian grid methods in the embedding space. The original closest point method (CPM) was designed for problems posed on static surfaces, however the solution of PDEs on moving surfaces is of considerable interest as well. Here we propose solving PDEs on moving surfaces using a combination of the CPM and a modification of the grid based particle method (Leung and Zhao (2009) [12]). The grid based particle method (GBPM) represents and tracks surfaces using meshless particles and an Eulerian reference grid. Our modification of the GBPM introduces a reconstruction step into the original method to ensure that all the grid points within a computational tube surrounding the surface are active. We present a number of examples to illustrate the numerical convergence properties of our combined method. Experiments for advection-diffusion equations that are strongly coupled to the velocity of the surface are also presented.

Experimental comparison and validation of hot-ball method with guarded hot plate method on polyurethane foams

NASA Astrophysics Data System (ADS)

Hudec, Ján; Glorieux, Christ; Dieška, Peter; Kubičár, Ľudovít

2016-07-01

The Hot-ball method is an innovative transient method for measuring thermophysical properties. The principle is based on heating of a small ball, incorporated in measured medium, by constant heating power and simultaneous measuring of the ball's temperature response since the heating was initiated. The shape of the temperature response depends on thermophysical properties of the medium, where the sensor is placed. This method is patented by Institute of Physics, SAS, where the method and sensors based on this method are being developed. At the beginning of the development of sensors for this method we were oriented on monitoring applications, where relative precision is much more important than accuracy. Meanwhile, the quality of sensors was improved good enough to be used for a new application - absolute measuring of thermophysical parameters of low thermally conductive materials. This paper describes experimental verification and validation of measurement by hot-ball method. Thanks to cooperation with Laboratory of Soft Matter and Biophysics of Catholic University of Leuven in Belgium, established Guarded Hot Plate method was used as a reference. Details about measuring setups, description of the experiments and results of the comparison are presented.

Statokinesigram normalization method.

PubMed

de Oliveira, José Magalhães

2017-02-01

Stabilometry is a technique that aims to study the body sway of human subjects, employing a force platform. The signal obtained from this technique refers to the position of the foot base ground-reaction vector, known as the center of pressure (CoP). The parameters calculated from the signal are used to quantify the displacement of the CoP over time; there is a large variability, both between and within subjects, which prevents the definition of normative values. The intersubject variability is related to differences between subjects in terms of their anthropometry, in conjunction with their muscle activation patterns (biomechanics); and the intrasubject variability can be caused by a learning effect or fatigue. Age and foot placement on the platform are also known to influence variability. Normalization is the main method used to decrease this variability and to bring distributions of adjusted values into alignment. In 1996, O'Malley proposed three normalization techniques to eliminate the effect of age and anthropometric factors from temporal-distance parameters of gait. These techniques were adopted to normalize the stabilometric signal by some authors. This paper proposes a new method of normalization of stabilometric signals to be applied in balance studies. The method was applied to a data set collected in a previous study, and the results of normalized and nonnormalized signals were compared. The results showed that the new method, if used in a well-designed experiment, can eliminate undesirable correlations between the analyzed parameters and the subjects' characteristics and show only the experimental conditions' effects.

Comparison of two fractal interpolation methods

NASA Astrophysics Data System (ADS)

Fu, Yang; Zheng, Zeyu; Xiao, Rui; Shi, Haibo

2017-03-01

As a tool for studying complex shapes and structures in nature, fractal theory plays a critical role in revealing the organizational structure of the complex phenomenon. Numerous fractal interpolation methods have been proposed over the past few decades, but they differ substantially in the form features and statistical properties. In this study, we simulated one- and two-dimensional fractal surfaces by using the midpoint displacement method and the Weierstrass-Mandelbrot fractal function method, and observed great differences between the two methods in the statistical characteristics and autocorrelation features. From the aspect of form features, the simulations of the midpoint displacement method showed a relatively flat surface which appears to have peaks with different height as the fractal dimension increases. While the simulations of the Weierstrass-Mandelbrot fractal function method showed a rough surface which appears to have dense and highly similar peaks as the fractal dimension increases. From the aspect of statistical properties, the peak heights from the Weierstrass-Mandelbrot simulations are greater than those of the middle point displacement method with the same fractal dimension, and the variances are approximately two times larger. When the fractal dimension equals to 1.2, 1.4, 1.6, and 1.8, the skewness is positive with the midpoint displacement method and the peaks are all convex, but for the Weierstrass-Mandelbrot fractal function method the skewness is both positive and negative with values fluctuating in the vicinity of zero. The kurtosis is less than one with the midpoint displacement method, and generally less than that of the Weierstrass-Mandelbrot fractal function method. The autocorrelation analysis indicated that the simulation of the midpoint displacement method is not periodic with prominent randomness, which is suitable for simulating aperiodic surface. While the simulation of the Weierstrass-Mandelbrot fractal function method has

Methods for chromosome-specific staining

DOEpatents

Gray, J.W.; Pinkel, D.

1995-09-05

Methods and compositions for chromosome-specific staining are provided. Compositions comprise heterogeneous mixtures of labeled nucleic acid fragments having substantially complementary base sequences to unique sequence regions of the chromosomal DNA for which their associated staining reagent is specific. Methods include ways for making the chromosome-specific staining compositions of the invention, and methods for applying the staining compositions to chromosomes. 3 figs.

Development of the Ion Exchange-Gravimetric Method for Sodium in Serum as a Definitive Method

PubMed Central

Moody, John R.; Vetter, Thomas W.

1996-01-01

An ion exchange-gravimetric method, previously developed as a National Committee for Clinical Laboratory Standards (NCCLS) reference method for the determination of sodium in human serum, has been re-evaluated and improved. Sources of analytical error in this method have been examined more critically and the overall uncertainties decreased. Additionally, greater accuracy and repeatability have been achieved by the application of this definitive method to a sodium chloride reference material. In this method sodium in serum is ion-exchanged, selectively eluted and converted to a weighable precipitate as Na2SO4. Traces of sodium eluting before or after the main fraction, and precipitate contaminants are determined instrumentally. Co-precipitating contaminants contribute less than 0.1 % while the analyte lost to other eluted ion-exchange fractions contributes less than 0.02 % to the total precipitate mass. With improvements, the relative expanded uncertainty (k = 2) of the method, as applied to serum, is 0.3 % to 0.4 % and is less than 0.1 % when applied to a sodium chloride reference material. PMID:27805122

Numerical Methods for 2-Dimensional Modeling

DTIC Science & Technology

1980-12-01

high-order finite element methods, and a multidimensional version of the method of lines, both utilizing an optimized stiff integrator for the time...integration. The finite element methods have proved disappointing, but the method of lines has provided an unexpectedly large gain in speed. Two...diffusion problems with the same number of unknowns (a 21 x 41 grid), solved by second-order finite element methods, took over seven minutes on the Cray-i

Illustrated surface mining methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1979-01-01

This manual provides a visual synopsis of surface coal mining methods in the United States. The manual presents various surface mining methods and techniques through artist renderings and appropriate descriptions. The productive coal fields of the United States were divided into four regions according to geology and physiography. A glossay of terminology is included. (DP)

7 CFR 91.23 - Analytical methods.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 3 2014-01-01 2014-01-01 false Analytical methods. 91.23 Section 91.23 Agriculture... SERVICES AND GENERAL INFORMATION Method Manuals § 91.23 Analytical methods. Most analyses are performed according to approved procedures described in manuals of standardized methodology. These standard methods...

7 CFR 91.23 - Analytical methods.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 3 2011-01-01 2011-01-01 false Analytical methods. 91.23 Section 91.23 Agriculture... SERVICES AND GENERAL INFORMATION Method Manuals § 91.23 Analytical methods. Most analyses are performed according to approved procedures described in manuals of standardized methodology. These standard methods...

7 CFR 91.23 - Analytical methods.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 3 2013-01-01 2013-01-01 false Analytical methods. 91.23 Section 91.23 Agriculture... SERVICES AND GENERAL INFORMATION Method Manuals § 91.23 Analytical methods. Most analyses are performed according to approved procedures described in manuals of standardized methodology. These standard methods...

Mixed Methods, Triangulation, and Causal Explanation

ERIC Educational Resources Information Center

Howe, Kenneth R.

2012-01-01

This article distinguishes a disjunctive conception of mixed methods/triangulation, which brings different methods to bear on different questions, from a conjunctive conception, which brings different methods to bear on the same question. It then examines a more inclusive, holistic conception of mixed methods/triangulation that accommodates…

Methods of Feminist Family Therapy Supervision.

ERIC Educational Resources Information Center

Prouty, Anne M.; Thomas, Volker; Johnson, Scott; Long, Janie K.

2001-01-01

Presents three supervision methods which emerged from a qualitative study of the experiences of feminist family therapy supervisors and the therapists they supervised: the supervision contract, collaborative methods, and hierarchical methods. Provides a description of the participants' experiences of these methods and discusses their fit with…

Relationships between the generalized functional method and other methods of nonimaging optical design.

PubMed

Bortz, John; Shatz, Narkis

2011-04-01

The recently developed generalized functional method provides a means of designing nonimaging concentrators and luminaires for use with extended sources and receivers. We explore the mathematical relationships between optical designs produced using the generalized functional method and edge-ray, aplanatic, and simultaneous multiple surface (SMS) designs. Edge-ray and dual-surface aplanatic designs are shown to be special cases of generalized functional designs. In addition, it is shown that dual-surface SMS designs are closely related to generalized functional designs and that certain computational advantages accrue when the two design methods are combined. A number of examples are provided. © 2011 Optical Society of America

48 CFR 7.402 - Acquisition methods.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Acquisition methods. 7.402... ACQUISITION PLANNING Equipment Lease or Purchase 7.402 Acquisition methods. (a) Purchase method. (1) Generally, the purchase method is appropriate if the equipment will be used beyond the point in time when...

7 CFR 58.644 - Test methods.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 3 2012-01-01 2012-01-01 false Test methods. 58.644 Section 58.644 Agriculture... Procedures § 58.644 Test methods. (a) Microbiological. Microbiological determinations shall be made in accordance with the methods described in the latest edition of Standard Methods for the Examination of Dairy...

7 CFR 58.644 - Test methods.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 3 2011-01-01 2011-01-01 false Test methods. 58.644 Section 58.644 Agriculture... Procedures § 58.644 Test methods. (a) Microbiological. Microbiological determinations shall be made in accordance with the methods described in the latest edition of Standard Methods for the Examination of Dairy...

7 CFR 94.303 - Analytical methods.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 3 2011-01-01 2011-01-01 false Analytical methods. 94.303 Section 94.303 Agriculture... POULTRY AND EGG PRODUCTS Processed Poultry Products § 94.303 Analytical methods. The analytical methods... latest edition of the Official Methods of Analysis of AOAC INTERNATIONAL, Suite 500, 481 North Frederick...

7 CFR 94.303 - Analytical methods.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Analytical methods. 94.303 Section 94.303 Agriculture... POULTRY AND EGG PRODUCTS Processed Poultry Products § 94.303 Analytical methods. The analytical methods... latest edition of the Official Methods of Analysis of AOAC INTERNATIONAL, Suite 500, 481 North Frederick...

48 CFR 7.402 - Acquisition methods.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Acquisition methods. 7.402... ACQUISITION PLANNING Equipment Lease or Purchase 7.402 Acquisition methods. (a) Purchase method. (1) Generally, the purchase method is appropriate if the equipment will be used beyond the point in time when...

7 CFR 94.303 - Analytical methods.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 3 2012-01-01 2012-01-01 false Analytical methods. 94.303 Section 94.303 Agriculture... POULTRY AND EGG PRODUCTS Processed Poultry Products § 94.303 Analytical methods. The analytical methods... latest edition of the Official Methods of Analysis of AOAC INTERNATIONAL, Suite 500, 481 North Frederick...

7 CFR 94.303 - Analytical methods.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 3 2013-01-01 2013-01-01 false Analytical methods. 94.303 Section 94.303 Agriculture... POULTRY AND EGG PRODUCTS Processed Poultry Products § 94.303 Analytical methods. The analytical methods... latest edition of the Official Methods of Analysis of AOAC INTERNATIONAL, Suite 500, 481 North Frederick...

7 CFR 94.303 - Analytical methods.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 3 2014-01-01 2014-01-01 false Analytical methods. 94.303 Section 94.303 Agriculture... POULTRY AND EGG PRODUCTS Processed Poultry Products § 94.303 Analytical methods. The analytical methods... latest edition of the Official Methods of Analysis of AOAC INTERNATIONAL, Suite 500, 481 North Frederick...

48 CFR 7.402 - Acquisition methods.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Acquisition methods. 7.402... ACQUISITION PLANNING Equipment Lease or Purchase 7.402 Acquisition methods. (a) Purchase method. (1) Generally, the purchase method is appropriate if the equipment will be used beyond the point in time when...

7 CFR 58.644 - Test methods.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 3 2013-01-01 2013-01-01 false Test methods. 58.644 Section 58.644 Agriculture... Procedures § 58.644 Test methods. (a) Microbiological. Microbiological determinations shall be made in accordance with the methods described in the latest edition of Standard Methods for the Examination of Dairy...

7 CFR 58.644 - Test methods.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Test methods. 58.644 Section 58.644 Agriculture... Procedures § 58.644 Test methods. (a) Microbiological. Microbiological determinations shall be made in accordance with the methods described in the latest edition of Standard Methods for the Examination of Dairy...

7 CFR 58.644 - Test methods.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 3 2014-01-01 2014-01-01 false Test methods. 58.644 Section 58.644 Agriculture... Procedures § 58.644 Test methods. (a) Microbiological. Microbiological determinations shall be made in accordance with the methods described in the latest edition of Standard Methods for the Examination of Dairy...

48 CFR 7.402 - Acquisition methods.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Acquisition methods. 7.402... ACQUISITION PLANNING Equipment Lease or Purchase 7.402 Acquisition methods. (a) Purchase method. (1) Generally, the purchase method is appropriate if the equipment will be used beyond the point in time when...

48 CFR 7.402 - Acquisition methods.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Acquisition methods. 7.402... ACQUISITION PLANNING Equipment Lease or Purchase 7.402 Acquisition methods. (a) Purchase method. (1) Generally, the purchase method is appropriate if the equipment will be used beyond the point in time when...

78 FR 22540 - Notice of Public Meeting/Webinar: EPA Method Development Update on Drinking Water Testing Methods...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-16

...: EPA Method Development Update on Drinking Water Testing Methods for Contaminant Candidate List... Division will describe methods currently in development for many CCL contaminants, with an expectation that several of these methods will support future cycles of the Unregulated Contaminant Monitoring Rule (UCMR...

Image portion identification methods, image parsing methods, image parsing systems, and articles of manufacture

DOEpatents

Lassahn, Gordon D.; Lancaster, Gregory D.; Apel, William A.; Thompson, Vicki S.

2013-01-08

Image portion identification methods, image parsing methods, image parsing systems, and articles of manufacture are described. According to one embodiment, an image portion identification method includes accessing data regarding an image depicting a plurality of biological substrates corresponding to at least one biological sample and indicating presence of at least one biological indicator within the biological sample and, using processing circuitry, automatically identifying a portion of the image depicting one of the biological substrates but not others of the biological substrates.

Why, and how, mixed methods research is undertaken in health services research in England: a mixed methods study

PubMed Central

O'Cathain, Alicia; Murphy, Elizabeth; Nicholl, Jon

2007-01-01

Background Recently, there has been a surge of international interest in combining qualitative and quantitative methods in a single study – often called mixed methods research. It is timely to consider why and how mixed methods research is used in health services research (HSR). Methods Documentary analysis of proposals and reports of 75 mixed methods studies funded by a research commissioner of HSR in England between 1994 and 2004. Face-to-face semi-structured interviews with 20 researchers sampled from these studies. Results 18% (119/647) of HSR studies were classified as mixed methods research. In the documentation, comprehensiveness was the main driver for using mixed methods research, with researchers wanting to address a wider range of questions than quantitative methods alone would allow. Interviewees elaborated on this, identifying the need for qualitative research to engage with the complexity of health, health care interventions, and the environment in which studies took place. Motivations for adopting a mixed methods approach were not always based on the intrinsic value of mixed methods research for addressing the research question; they could be strategic, for example, to obtain funding. Mixed methods research was used in the context of evaluation, including randomised and non-randomised designs; survey and fieldwork exploratory studies; and instrument development. Studies drew on a limited number of methods – particularly surveys and individual interviews – but used methods in a wide range of roles. Conclusion Mixed methods research is common in HSR in the UK. Its use is driven by pragmatism rather than principle, motivated by the perceived deficit of quantitative methods alone to address the complexity of research in health care, as well as other more strategic gains. Methods are combined in a range of contexts, yet the emerging methodological contributions from HSR to the field of mixed methods research are currently limited to the single

Comparison of infusion pumps calibration methods

NASA Astrophysics Data System (ADS)

Batista, Elsa; Godinho, Isabel; do Céu Ferreira, Maria; Furtado, Andreia; Lucas, Peter; Silva, Claudia

2017-12-01

Nowadays, several types of infusion pump are commonly used for drug delivery, such as syringe pumps and peristaltic pumps. These instruments present different measuring features and capacities according to their use and therapeutic application. In order to ensure the metrological traceability of these flow and volume measuring equipment, it is necessary to use suitable calibration methods and standards. Two different calibration methods can be used to determine the flow error of infusion pumps. One is the gravimetric method, considered as a primary method, commonly used by National Metrology Institutes. The other calibration method, a secondary method, relies on an infusion device analyser (IDA) and is typically used by hospital maintenance offices. The suitability of the IDA calibration method was assessed by testing several infusion instruments at different flow rates using the gravimetric method. In addition, a measurement comparison between Portuguese Accredited Laboratories and hospital maintenance offices was performed under the coordination of the Portuguese Institute for Quality, the National Metrology Institute. The obtained results were directly related to the used calibration method and are presented in this paper. This work has been developed in the framework of the EURAMET projects EMRP MeDD and EMPIR 15SIP03.

Novel hermetic packaging methods for MOEMS

NASA Astrophysics Data System (ADS)

Stark, David

2003-01-01

Hermetic packaging of micro-optoelectromechanical systems (MOEMS) is an immature technology, lacking industry-consensus methods and standards. Off-the-shelf, catalog window assemblies are not yet available. Window assemblies are in general custom designed and manufactured for each new product, resulting in longer than acceptable cycle times, high procurement costs and questionable reliability. There are currently two dominant window-manufacturing methods wherein a metal frame is attached to glass, as well as a third, less-used method. The first method creates a glass-to-metal seal by heating the glass above its Tg to fuse it to the frame. The second method involves first metallizing the glass where it is to be attached to the frame, and then soldering the glass to the frame. The third method employs solder-glass to bond the glass to the frame. A novel alternative with superior features compared to the three previously described window-manufacturing methods is proposed. The new approach lends itself to a plurality of glass-to-metal attachment techniques. Benefits include lower temperature processing than two of the current methods and potentially more cost-effective manufacturing than all three of today"s attachment methods.

Robust and Accurate Shock Capturing Method for High-Order Discontinuous Galerkin Methods

NASA Technical Reports Server (NTRS)

Atkins, Harold L.; Pampell, Alyssa

2011-01-01

A simple yet robust and accurate approach for capturing shock waves using a high-order discontinuous Galerkin (DG) method is presented. The method uses the physical viscous terms of the Navier-Stokes equations as suggested by others; however, the proposed formulation of the numerical viscosity is continuous and compact by construction, and does not require the solution of an auxiliary diffusion equation. This work also presents two analyses that guided the formulation of the numerical viscosity and certain aspects of the DG implementation. A local eigenvalue analysis of the DG discretization applied to a shock containing element is used to evaluate the robustness of several Riemann flux functions, and to evaluate algorithm choices that exist within the underlying DG discretization. A second analysis examines exact solutions to the DG discretization in a shock containing element, and identifies a "model" instability that will inevitably arise when solving the Euler equations using the DG method. This analysis identifies the minimum viscosity required for stability. The shock capturing method is demonstrated for high-speed flow over an inviscid cylinder and for an unsteady disturbance in a hypersonic boundary layer. Numerical tests are presented that evaluate several aspects of the shock detection terms. The sensitivity of the results to model parameters is examined with grid and order refinement studies.

Methods of Motivational Teaching

ERIC Educational Resources Information Center

Malouff, John M.; Rooke, Sally E.; Schutte, Nicola S.; Foster, Roxanne M.; Bhullar, Navjot

2008-01-01

As teachers, we want to motivate our students to learn during a unit and to continue learning about the topic after the unit ends. This article describes about a hundred methods we use to help motivate students to learn. The methods form 12 categories: (1) making content relevant to student values and goals; (2) helping students achieve their…

Methods of expanding bacteriophage host-range and bacteriophage produced by the methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crown, Kevin K.; Santarpia, Joshua

A method of producing novel bacteriophages with expanded host-range and bacteriophages with expanded host ranges are disclosed. The method produces mutant phage strains which are infectious to a second host and can be more infectious to their natural host than in their natural state. The method includes repeatedly passaging a selected phage strain into bacterial cultures that contain varied ratios of its natural host bacterial strain with a bacterial strain that the phage of interest is unable to infect; the target-host. After each passage the resulting phage are purified and screened for activity against the target-host via double-overlay assays. Whenmore » mutant phages that are shown to infect the target-host are discovered, they are further propagated in culture that contains only the target-host to produce a stock of the resulting mutant phage.« less

30 CFR 75.203 - Mining methods.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Mining methods. 75.203 Section 75.203 Mineral... SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.203 Mining methods. (a) The method of mining... faulty pillar recovery methods. Pillar dimensions shall be compatible with effective control of the roof...

7 CFR 98.4 - Analytical methods.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 3 2011-01-01 2011-01-01 false Analytical methods. 98.4 Section 98.4 Agriculture....4 Analytical methods. (a) The majority of analytical methods used by the USDA laboratories to perform analyses of meat, meat food products and MRE's are listed as follows: (1) Official Methods of...

7 CFR 98.4 - Analytical methods.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Analytical methods. 98.4 Section 98.4 Agriculture....4 Analytical methods. (a) The majority of analytical methods used by the USDA laboratories to perform analyses of meat, meat food products and MRE's are listed as follows: (1) Official Methods of...

30 CFR 75.203 - Mining methods.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Mining methods. 75.203 Section 75.203 Mineral... SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.203 Mining methods. (a) The method of mining... faulty pillar recovery methods. Pillar dimensions shall be compatible with effective control of the roof...

30 CFR 75.203 - Mining methods.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Mining methods. 75.203 Section 75.203 Mineral... SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.203 Mining methods. (a) The method of mining... faulty pillar recovery methods. Pillar dimensions shall be compatible with effective control of the roof...

7 CFR 98.4 - Analytical methods.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 3 2012-01-01 2012-01-01 false Analytical methods. 98.4 Section 98.4 Agriculture....4 Analytical methods. (a) The majority of analytical methods used by the USDA laboratories to perform analyses of meat, meat food products and MRE's are listed as follows: (1) Official Methods of...

7 CFR 98.4 - Analytical methods.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 3 2013-01-01 2013-01-01 false Analytical methods. 98.4 Section 98.4 Agriculture....4 Analytical methods. (a) The majority of analytical methods used by the USDA laboratories to perform analyses of meat, meat food products and MRE's are listed as follows: (1) Official Methods of...

30 CFR 75.203 - Mining methods.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Mining methods. 75.203 Section 75.203 Mineral... SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.203 Mining methods. (a) The method of mining... faulty pillar recovery methods. Pillar dimensions shall be compatible with effective control of the roof...

30 CFR 75.203 - Mining methods.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Mining methods. 75.203 Section 75.203 Mineral... SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.203 Mining methods. (a) The method of mining... faulty pillar recovery methods. Pillar dimensions shall be compatible with effective control of the roof...

Evaluation Measures and Methods: Some Intersections.

ERIC Educational Resources Information Center

Elliott, John

The literature is reviewed for four combinations of evaluation measures and methods: traditional methods with traditional measures (T-Meth/T-Mea), nontraditional methods with traditional measures (N-Meth/T-Mea), traditional measures with nontraditional measures (T-Meth/N-Mea), and nontraditional methods with nontraditional measures (N-Meth/N-Mea).…

Method for alignment of microwires

DOE Office of Scientific and Technical Information (OSTI.GOV)

Beardslee, Joseph A.; Lewis, Nathan S.; Sadtler, Bryce

2017-01-24

A method of aligning microwires includes modifying the microwires so they are more responsive to a magnetic field. The method also includes using a magnetic field so as to magnetically align the microwires. The method can further include capturing the microwires in a solid support structure that retains the longitudinal alignment of the microwires when the magnetic field is not applied to the microwires.

Qualitative Research Methods in Education and Educational Technology. Research Methods for Educational Technology

ERIC Educational Resources Information Center

Willis, Jerry W.

2008-01-01

"Qualitative Research Methods in Education and Educational Technology" was written for students and scholars interested in exploring the many qualitative methods developed over the last 50 years in the social sciences. The book does not stop, however, at the boundaries of the social sciences. Social scientists now consume and use research methods…

A Multifunctional Interface Method for Coupling Finite Element and Finite Difference Methods: Two-Dimensional Scalar-Field Problems

NASA Technical Reports Server (NTRS)

Ransom, Jonathan B.

2002-01-01

A multifunctional interface method with capabilities for variable-fidelity modeling and multiple method analysis is presented. The methodology provides an effective capability by which domains with diverse idealizations can be modeled independently to exploit the advantages of one approach over another. The multifunctional method is used to couple independently discretized subdomains, and it is used to couple the finite element and the finite difference methods. The method is based on a weighted residual variational method and is presented for two-dimensional scalar-field problems. A verification test problem and a benchmark application are presented, and the computational implications are discussed.

Optimization Methods in Sherpa

NASA Astrophysics Data System (ADS)

Siemiginowska, Aneta; Nguyen, Dan T.; Doe, Stephen M.; Refsdal, Brian L.

2009-09-01

Forward fitting is a standard technique used to model X-ray data. A statistic, usually assumed weighted chi^2 or Poisson likelihood (e.g. Cash), is minimized in the fitting process to obtain a set of the best model parameters. Astronomical models often have complex forms with many parameters that can be correlated (e.g. an absorbed power law). Minimization is not trivial in such setting, as the statistical parameter space becomes multimodal and finding the global minimum is hard. Standard minimization algorithms can be found in many libraries of scientific functions, but they are usually focused on specific functions. However, Sherpa designed as general fitting and modeling application requires very robust optimization methods that can be applied to variety of astronomical data (X-ray spectra, images, timing, optical data etc.). We developed several optimization algorithms in Sherpa targeting a wide range of minimization problems. Two local minimization methods were built: Levenberg-Marquardt algorithm was obtained from MINPACK subroutine LMDIF and modified to achieve the required robustness; and Nelder-Mead simplex method has been implemented in-house based on variations of the algorithm described in the literature. A global search Monte-Carlo method has been implemented following a differential evolution algorithm presented by Storn and Price (1997). We will present the methods in Sherpa and discuss their usage cases. We will focus on the application to Chandra data showing both 1D and 2D examples. This work is supported by NASA contract NAS8-03060 (CXC).

Geophysical methods

USDA-ARS?s Scientific Manuscript database

Near-surface geophysical methods have become have become important tools for agriculture. Geophysics employed for agriculture tends to be heavily focused on a 2 m zone directly beneath the ground surface, which includes the crop root zone and all, or at least most, of the soil profile. Resistivity...

Evaluation and comparison of Abbott Jaffe and enzymatic creatinine methods: Could the old method meet the new requirements?

PubMed

Küme, Tuncay; Sağlam, Barıs; Ergon, Cem; Sisman, Ali Rıza

2018-01-01

The aim of this study is to evaluate and compare the analytical performance characteristics of the two creatinine methods based on the Jaffe and enzymatic methods. Two original creatinine methods, Jaffe and enzymatic, were evaluated on Architect c16000 automated analyzer via limit of detection (LOD) and limit of quantitation (LOQ), linearity, intra-assay and inter-assay precision, and comparability in serum and urine samples. The method comparison and bias estimation using patient samples according to CLSI guideline were performed on 230 serum and 141 urine samples by analyzing on the same auto-analyzer. The LODs were determined as 0.1 mg/dL for both serum methods and as 0.25 and 0.07 mg/dL for the Jaffe and the enzymatic urine method respectively. The LOQs were similar with 0.05 mg/dL value for both serum methods, and enzymatic urine method had a lower LOQ than Jaffe urine method, values at 0.5 and 2 mg/dL respectively. Both methods were linear up to 65 mg/dL for serum and 260 mg/dL for urine. The intra-assay and inter-assay precision data were under desirable levels in both methods. The higher correlations were determined between two methods in serum and urine (r=.9994, r=.9998 respectively). On the other hand, Jaffe method gave the higher creatinine results than enzymatic method, especially at the low concentrations in both serum and urine. Both Jaffe and enzymatic methods were found to meet the analytical performance requirements in routine use. However, enzymatic method was found to have better performance in low creatinine levels. © 2017 Wiley Periodicals, Inc.

Research on teaching methods.

PubMed

Oermann, M H

1990-01-01

Research on teaching methods in nursing education was categorized into studies on media, CAI, and other nontraditional instructional strategies. While the research differed, some generalizations may be made from the findings. Multimedia, whether it is used for individual or group instruction, is at least as effective as traditional instruction (lecture and lecture-discussion) in promoting cognitive learning, retention of knowledge, and performance. Further study is needed to identify variables that may influence learning and retention. While learner attitudes toward mediated instruction tended to be positive, investigators failed to control for the effect of novelty. Control over intervening variables was lacking in the majority of studies as well. Research indicated that CAI is as effective as other teaching methods in terms of knowledge gain and retention. Attitudes toward CAI tended to be favorable, with similar problems in measurement as those evidenced in studies of media. Chang (1986) also recommends that future research examine the impact of computer-video interactive instruction on students, faculty, and settings. Research is needed on experimental teaching methods, strategies for teaching problem solving and clinical judgment, and ways of improving the traditional lecture and discussion. Limited research in these areas makes generalizations impossible. There is a particular need for research on how to teach students the diagnostic reasoning process and encourage critical thinking, both in terms of appropriate teaching methods and the way in which those strategies should be used. It is interesting that few researchers studied lecture and lecture-discussion except as comparable teaching methods for research on other strategies. Additional research questions may be generated on lecture and discussion in relation to promoting concept learning, an understanding of nursing and other theories, transfer of knowledge, and development of cognitive skills. Few

7 CFR 93.4 - Analytical methods.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 3 2013-01-01 2013-01-01 false Analytical methods. 93.4 Section 93.4 Agriculture... PROCESSED FRUITS AND VEGETABLES Citrus Juices and Certain Citrus Products § 93.4 Analytical methods. (a) The majority of analytical methods for citrus products are found in the Official Methods of Analysis of AOAC...

7 CFR 93.4 - Analytical methods.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 3 2014-01-01 2014-01-01 false Analytical methods. 93.4 Section 93.4 Agriculture... PROCESSED FRUITS AND VEGETABLES Citrus Juices and Certain Citrus Products § 93.4 Analytical methods. (a) The majority of analytical methods for citrus products are found in the Official Methods of Analysis of AOAC...

7 CFR 93.4 - Analytical methods.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Analytical methods. 93.4 Section 93.4 Agriculture... PROCESSED FRUITS AND VEGETABLES Citrus Juices and Certain Citrus Products § 93.4 Analytical methods. (a) The majority of analytical methods for citrus products are found in the Official Methods of Analysis of AOAC...

7 CFR 98.4 - Analytical methods.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 3 2014-01-01 2014-01-01 false Analytical methods. 98.4 Section 98.4 Agriculture... Analytical methods. (a) The majority of analytical methods used by the USDA laboratories to perform analyses of meat, meat food products and MREs are listed as follows: (1) Official Methods of Analysis of AOAC...

7 CFR 93.4 - Analytical methods.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 3 2011-01-01 2011-01-01 false Analytical methods. 93.4 Section 93.4 Agriculture... PROCESSED FRUITS AND VEGETABLES Citrus Juices and Certain Citrus Products § 93.4 Analytical methods. (a) The majority of analytical methods for citrus products are found in the Official Methods of Analysis of AOAC...

7 CFR 93.4 - Analytical methods.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 3 2012-01-01 2012-01-01 false Analytical methods. 93.4 Section 93.4 Agriculture... PROCESSED FRUITS AND VEGETABLES Citrus Juices and Certain Citrus Products § 93.4 Analytical methods. (a) The majority of analytical methods for citrus products are found in the Official Methods of Analysis of AOAC...

Geophysical methods in Geology. Second edition

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sharma, P.V.

This book presents an introduction to the methods of geophysics and their application to geological problems. The text emphasizes the broader aspects of geophysics, including the way in which geophysical methods help solve structural, correlational, and geochromological problems. Stress is laid on the principles and applications of methods rather than on instrumental techniques. This edition includes coverage of recent developments in geophysics and geology. New topics are introduced, including paleomagnetic methods, electromagnetic methods, microplate tectronics, and the use of multiple geophysical techniques.

Methods of producing cermet materials and methods of utilizing same

DOEpatents

Kong, Peter C [Idaho Falls, ID

2008-12-30

Methods of fabricating cermet materials and methods of utilizing the same such as in filtering particulate and gaseous pollutants from internal combustion engines having intermetallic and ceramic phases. The cermet material may be made from a transition metal aluminide phase and an alumina phase. The mixture may be pressed to form a green compact body and then heated in a nitrogen-containing atmosphere so as to melt aluminum particles and form the cermet. Filler materials may be added to increase the porosity or tailor the catalytic properties of the cermet material. Additionally, the cermet material may be reinforced with fibers or screens. The cermet material may also be formed so as to pass an electrical current therethrough to heat the material during use.

Methods of fabricating cermet materials and methods of utilizing same

DOEpatents

Kong, Peter C.

2006-04-04

Methods of fabricating cermet materials and methods of utilizing the same such as in filtering particulate and gaseous pollutants from internal combustion engines having intermetallic and ceramic phases. The cermet material may be made from a transition metal aluminide phase and an aluminia phase. The mixture may be pressed to form a green compact body and then heated in a nitrogen-containing atmosphere so as to melt aluminum particles and form the cermet. Filler materials may be added to increase the porosity or tailor the catalytic properties of the cermet material. Additionally, the cermet material may be reinforced with fibers or screens. The cermet material may also be formed so as to pass an electrical current therethrough to heat the material during use.

Why, and how, mixed methods research is undertaken in health services research in England: a mixed methods study.

PubMed

O'Cathain, Alicia; Murphy, Elizabeth; Nicholl, Jon

2007-06-14

Recently, there has been a surge of international interest in combining qualitative and quantitative methods in a single study--often called mixed methods research. It is timely to consider why and how mixed methods research is used in health services research (HSR). Documentary analysis of proposals and reports of 75 mixed methods studies funded by a research commissioner of HSR in England between 1994 and 2004. Face-to-face semi-structured interviews with 20 researchers sampled from these studies. 18% (119/647) of HSR studies were classified as mixed methods research. In the documentation, comprehensiveness was the main driver for using mixed methods research, with researchers wanting to address a wider range of questions than quantitative methods alone would allow. Interviewees elaborated on this, identifying the need for qualitative research to engage with the complexity of health, health care interventions, and the environment in which studies took place. Motivations for adopting a mixed methods approach were not always based on the intrinsic value of mixed methods research for addressing the research question; they could be strategic, for example, to obtain funding. Mixed methods research was used in the context of evaluation, including randomised and non-randomised designs; survey and fieldwork exploratory studies; and instrument development. Studies drew on a limited number of methods--particularly surveys and individual interviews--but used methods in a wide range of roles. Mixed methods research is common in HSR in the UK. Its use is driven by pragmatism rather than principle, motivated by the perceived deficit of quantitative methods alone to address the complexity of research in health care, as well as other more strategic gains. Methods are combined in a range of contexts, yet the emerging methodological contributions from HSR to the field of mixed methods research are currently limited to the single context of combining qualitative methods and

A survey on sleep assessment methods

PubMed Central

Silva, Josep; Cauli, Omar

2018-01-01

Purpose A literature review is presented that aims to summarize and compare current methods to evaluate sleep. Methods Current sleep assessment methods have been classified according to different criteria; e.g., objective (polysomnography, actigraphy…) vs. subjective (sleep questionnaires, diaries…), contact vs. contactless devices, and need for medical assistance vs. self-assessment. A comparison of validation studies is carried out for each method, identifying their sensitivity and specificity reported in the literature. Finally, the state of the market has also been reviewed with respect to customers’ opinions about current sleep apps. Results A taxonomy that classifies the sleep detection methods. A description of each method that includes the tendencies of their underlying technologies analyzed in accordance with the literature. A comparison in terms of precision of existing validation studies and reports. Discussion In order of accuracy, sleep detection methods may be arranged as follows: Questionnaire < Sleep diary < Contactless devices < Contact devices < Polysomnography A literature review suggests that current subjective methods present a sensitivity between 73% and 97.7%, while their specificity ranges in the interval 50%–96%. Objective methods such as actigraphy present a sensibility higher than 90%. However, their specificity is low compared to their sensitivity, being one of the limitations of such technology. Moreover, there are other factors, such as the patient’s perception of her or his sleep, that can be provided only by subjective methods. Therefore, sleep detection methods should be combined to produce a synergy between objective and subjective methods. The review of the market indicates the most valued sleep apps, but it also identifies problems and gaps, e.g., many hardware devices have not been validated and (especially software apps) should be studied before their clinical use. PMID:29844990

14 CFR 23.605 - Fabrication methods.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Fabrication methods. 23.605 Section 23.605... Fabrication methods. (a) The methods of fabrication used must produce consistently sound structures. If a... fabrication method must be substantiated by a test program. [Doc. No. 4080, 29 FR 17955, Dec. 18, 1964; 30 FR...

14 CFR 23.605 - Fabrication methods.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Fabrication methods. 23.605 Section 23.605... Fabrication methods. (a) The methods of fabrication used must produce consistently sound structures. If a... fabrication method must be substantiated by a test program. [Doc. No. 4080, 29 FR 17955, Dec. 18, 1964; 30 FR...

14 CFR 23.605 - Fabrication methods.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Fabrication methods. 23.605 Section 23.605... Fabrication methods. (a) The methods of fabrication used must produce consistently sound structures. If a... fabrication method must be substantiated by a test program. [Doc. No. 4080, 29 FR 17955, Dec. 18, 1964; 30 FR...

14 CFR 23.605 - Fabrication methods.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Fabrication methods. 23.605 Section 23.605... Fabrication methods. (a) The methods of fabrication used must produce consistently sound structures. If a... fabrication method must be substantiated by a test program. [Doc. No. 4080, 29 FR 17955, Dec. 18, 1964; 30 FR...

14 CFR 23.605 - Fabrication methods.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Fabrication methods. 23.605 Section 23.605... Fabrication methods. (a) The methods of fabrication used must produce consistently sound structures. If a... fabrication method must be substantiated by a test program. [Doc. No. 4080, 29 FR 17955, Dec. 18, 1964; 30 FR...

Stochastic Methods for Aircraft Design

NASA Technical Reports Server (NTRS)

Pelz, Richard B.; Ogot, Madara

1998-01-01

The global stochastic optimization method, simulated annealing (SA), was adapted and applied to various problems in aircraft design. The research was aimed at overcoming the problem of finding an optimal design in a space with multiple minima and roughness ubiquitous to numerically generated nonlinear objective functions. SA was modified to reduce the number of objective function evaluations for an optimal design, historically the main criticism of stochastic methods. SA was applied to many CFD/MDO problems including: low sonic-boom bodies, minimum drag on supersonic fore-bodies, minimum drag on supersonic aeroelastic fore-bodies, minimum drag on HSCT aeroelastic wings, FLOPS preliminary design code, another preliminary aircraft design study with vortex lattice aerodynamics, HSR complete aircraft aerodynamics. In every case, SA provided a simple, robust and reliable optimization method which found optimal designs in order 100 objective function evaluations. Perhaps most importantly, from this academic/industrial project, technology has been successfully transferred; this method is the method of choice for optimization problems at Northrop Grumman.

Methods for Scaling Icing Test Conditions

NASA Technical Reports Server (NTRS)

Anderson, David N.

1995-01-01

This report presents the results of tests at NASA Lewis to evaluate several methods to establish suitable alternative test conditions when the test facility limits the model size or operating conditions. The first method was proposed by Olsen. It can be applied when full-size models are tested and all the desired test conditions except liquid-water content can be obtained in the facility. The other two methods discussed are: a modification of the French scaling law and the AEDC scaling method. Icing tests were made with cylinders at both reference and scaled conditions representing mixed and glaze ice in the NASA Lewis Icing Research Tunnel. Reference and scale ice shapes were compared to evaluate each method. The Olsen method was tested with liquid-water content varying from 1.3 to .8 g/m(exp3). Over this range, ice shapes produced using the Olsen method were unchanged. The modified French and AEDC methods produced scaled ice shapes which approximated the reference shapes when model size was reduced to half the reference size for the glaze-ice cases tested.

WARGAMES AND THE SCIENTIFIC METHOD

DTIC Science & Technology

2017-04-06

AIR WAR COLLEGE AIR UNIVERSITY WARGAMES & THE SCIENTIFIC METHOD by Eric M. Murphy, Lieutenant Colonel, USAF A Research Report...than can be obtained by any method short of actual participation on the field of battle.”23 Robert Rubel has also observed that the learning here is...mechanics and objectives are not dissimilar when he suggests, “The logic and method of design…is first and foremost a collective research

Method of treating depression

DOEpatents

Henn, Fritz [East Patchogue, NY

2012-01-24

Methods for treatment of depression-related mood disorders in mammals, particularly humans are disclosed. The methods of the invention include administration of compounds capable of enhancing glutamate transporter activity in the brain of mammals suffering from depression. ATP-sensitive K.sup.+ channel openers and .beta.-lactam antibiotics are used to enhance glutamate transport and to treat depression-related mood disorders and depressive symptoms.

Method of treating depression

DOEpatents

Henn, Fritz

2013-04-09

Methods for treatment of depression-related mood disorders in mammals, particularly humans are disclosed. The methods of the invention include administration of compounds capable of enhancing glutamate transporter activity in the brain of mammals suffering from depression. ATP-sensitive K.sup.+ channel openers and .beta.-lactam antibiotics are used to enhance glutamate transport and to treat depression-related mood disorders and depressive symptoms.

Data center cooling method

DOEpatents

Chainer, Timothy J.; Dang, Hien P.; Parida, Pritish R.; Schultz, Mark D.; Sharma, Arun

2015-08-11

A method aspect for removing heat from a data center may use liquid coolant cooled without vapor compression refrigeration on a liquid cooled information technology equipment rack. The method may also include regulating liquid coolant flow to the data center through a range of liquid coolant flow values with a controller-apparatus based upon information technology equipment temperature threshold of the data center.

Bayesian methods in reliability

NASA Astrophysics Data System (ADS)

Sander, P.; Badoux, R.

1991-11-01

The present proceedings from a course on Bayesian methods in reliability encompasses Bayesian statistical methods and their computational implementation, models for analyzing censored data from nonrepairable systems, the traits of repairable systems and growth models, the use of expert judgment, and a review of the problem of forecasting software reliability. Specific issues addressed include the use of Bayesian methods to estimate the leak rate of a gas pipeline, approximate analyses under great prior uncertainty, reliability estimation techniques, and a nonhomogeneous Poisson process. Also addressed are the calibration sets and seed variables of expert judgment systems for risk assessment, experimental illustrations of the use of expert judgment for reliability testing, and analyses of the predictive quality of software-reliability growth models such as the Weibull order statistics.

40 CFR 63.547 - Test methods.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 9 2010-07-01 2010-07-01 false Test methods. 63.547 Section 63.547... Hazardous Air Pollutants from Secondary Lead Smelting § 63.547 Test methods. (a) The following test methods...), and 63.545(e): (1) Method 1 shall be used to select the sampling port location and the number of...

40 CFR 63.547 - Test methods.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 9 2011-07-01 2011-07-01 false Test methods. 63.547 Section 63.547... Hazardous Air Pollutants from Secondary Lead Smelting § 63.547 Test methods. (a) The following test methods...), and 63.545(e): (1) Method 1 shall be used to select the sampling port location and the number of...

Using mixed methods in health research

PubMed Central

Woodman, Jenny

2013-01-01

Summary Mixed methods research is the use of quantitative and qualitative methods in a single study or series of studies. It is an emergent methodology which is increasingly used by health researchers, especially within health services research. There is a growing literature on the theory, design and critical appraisal of mixed methods research. However, there are few papers that summarize this methodological approach for health practitioners who wish to conduct or critically engage with mixed methods studies. The objective of this paper is to provide an accessible introduction to mixed methods for clinicians and researchers unfamiliar with this approach. We present a synthesis of key methodological literature on mixed methods research, with examples from our own work and that of others, to illustrate the practical applications of this approach within health research. We summarize definitions of mixed methods research, the value of this approach, key aspects of study design and analysis, and discuss the potential challenges of combining quantitative and qualitative methods and data. One of the key challenges within mixed methods research is the successful integration of quantitative and qualitative data during analysis and interpretation. However, the integration of different types of data can generate insights into a research question, resulting in enriched understanding of complex health research problems. PMID:23885291

A new method of time difference measurement: The time difference method by dual phase coincidence points detection

NASA Technical Reports Server (NTRS)

Zhou, Wei

1993-01-01

In the high accurate measurement of periodic signals, the greatest common factor frequency and its characteristics have special functions. A method of time difference measurement - the time difference method by dual 'phase coincidence points' detection is described. This method utilizes the characteristics of the greatest common factor frequency to measure time or phase difference between periodic signals. It can suit a very wide frequency range. Measurement precision and potential accuracy of several picoseconds were demonstrated with this new method. The instrument based on this method is very simple, and the demand for the common oscillator is low. This method and instrument can be used widely.

Methods of Making Z-Shielding

NASA Technical Reports Server (NTRS)

Thomsen, III, Donald Laurence (Inventor); Cano, Roberto J. (Inventor); Jensen, Brian J. (Inventor); Hales, Stephen J. (Inventor); Alexa, Joel A. (Inventor)

2014-01-01

Methods of building Z-graded radiation shielding and covers. In one aspect, the method includes: providing a substrate surface having about medium Z-grade; plasma spraying a first metal having higher Z-grade than the substrate surface; and infusing a polymer layer to form a laminate. In another aspect, the method includes electro/electroless plating a first metal having higher Z-grade than the substrate surface. In other aspects, the methods include improving an existing electronics enclosure to build a Z-graded radiation shield by applying a temperature controller to at least part of the enclosure and affixing at least one layer of a first metal having higher Z-grade from the enclosure.

Persons Camp Using Interpolation Method

NASA Astrophysics Data System (ADS)

Tawfiq, Luma Naji Mohammed; Najm Abood, Israa

2018-05-01

The aim of this paper is to estimate the rate of contaminated soils by using suitable interpolation method as an alternative accurate tool to evaluate the concentration of heavy metals in soil then compared with standard universal value to determine the rate of contamination in the soil. In particular, interpolation methods are extensively applied in the models of the different phenomena where experimental data must be used in computer studies where expressions of those data are required. In this paper the extended divided difference method in two dimensions is used to solve suggested problem. Then, the modification method is applied to estimate the rate of contaminated soils of displaced persons camp in Diyala Governorate, in Iraq.

Peptides and methods against diabetes

DOEpatents

Albertini, Richard J.; Falta, Michael T.

2000-01-01

This invention relates to methods of preventing or reducing the severity of diabetes. In one embodiment, the method involves administering to the individual a peptide having substantially the sequence of a on-conserved region sequence of a T cell receptor present on the surface of T cells mediating diabetes or a fragment thereof, wherein the peptide or fragment is capable of causing an effect on the immune system to regulate the T cells. In particular, the T cell receptor has the V.beta. regional V.beta.6 or V.beta.14. In another embodiment, the method involves gene therapy. The invention also relates to methods of diagnosing diabetes by determining the presence of diabetes predominant T cell receptors.

NASA Formal Methods Workshop, 1990

NASA Technical Reports Server (NTRS)

Butler, Ricky W. (Compiler)

1990-01-01

The workshop brought together researchers involved in the NASA formal methods research effort for detailed technical interchange and provided a mechanism for interaction with representatives from the FAA and the aerospace industry. The workshop also included speakers from industry to debrief the formal methods researchers on the current state of practice in flight critical system design, verification, and certification. The goals were: define and characterize the verification problem for ultra-reliable life critical flight control systems and the current state of practice in industry today; determine the proper role of formal methods in addressing these problems, and assess the state of the art and recent progress toward applying formal methods to this area.

Unorthodox theoretical methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nedd, Sean

2012-01-01

The use of the ReaxFF force field to correlate with NMR mobilities of amine catalytic substituents on a mesoporous silica nanosphere surface is considered. The interfacing of the ReaxFF force field within the Surface Integrated Molecular Orbital/Molecular Mechanics (SIMOMM) method, in order to replicate earlier SIMOMM published data and to compare with the ReaxFF data, is discussed. The development of a new correlation consistent Composite Approach (ccCA) is presented, which incorporates the completely renormalized coupled cluster method with singles, doubles and non-iterative triples corrections towards the determination of heats of formations and reaction pathways which contain biradical species.

Imaging quality analysis of computer-generated holograms using the point-based method and slice-based method

NASA Astrophysics Data System (ADS)

Zhang, Zhen; Chen, Siqing; Zheng, Huadong; Sun, Tao; Yu, Yingjie; Gao, Hongyue; Asundi, Anand K.

2017-06-01

Computer holography has made a notably progress in recent years. The point-based method and slice-based method are chief calculation algorithms for generating holograms in holographic display. Although both two methods are validated numerically and optically, the differences of the imaging quality of these methods have not been specifically analyzed. In this paper, we analyze the imaging quality of computer-generated phase holograms generated by point-based Fresnel zone plates (PB-FZP), point-based Fresnel diffraction algorithm (PB-FDA) and slice-based Fresnel diffraction algorithm (SB-FDA). The calculation formula and hologram generation with three methods are demonstrated. In order to suppress the speckle noise, sequential phase-only holograms are generated in our work. The results of reconstructed images numerically and experimentally are also exhibited. By comparing the imaging quality, the merits and drawbacks with three methods are analyzed. Conclusions are given by us finally.

Methods for environmental change; an exploratory study

PubMed Central

2012-01-01

Background While the interest of health promotion researchers in change methods directed at the target population has a long tradition, interest in change methods directed at the environment is still developing. In this survey, the focus is on methods for environmental change; especially about how these are composed of methods for individual change (‘Bundling’) and how within one environmental level, organizations, methods differ when directed at the management (‘At’) or applied by the management (‘From’). Methods The first part of this online survey dealt with examining the ‘bundling’ of individual level methods to methods at the environmental level. The question asked was to what extent the use of an environmental level method would involve the use of certain individual level methods. In the second part of the survey the question was whether there are differences between applying methods directed ‘at’ an organization (for instance, by a health promoter) versus ‘from’ within an organization itself. All of the 20 respondents are experts in the field of health promotion. Results Methods at the individual level are frequently bundled together as part of a method at a higher ecological level. A number of individual level methods are popular as part of most of the environmental level methods, while others are not chosen very often. Interventions directed at environmental agents often have a strong focus on the motivational part of behavior change. There are different approaches targeting a level or being targeted from a level. The health promoter will use combinations of motivation and facilitation. The manager will use individual level change methods focusing on self-efficacy and skills. Respondents think that any method may be used under the right circumstances, although few endorsed coercive methods. Conclusions Taxonomies of theoretical change methods for environmental change should include combinations of individual level methods that may

Methods and Technologies Branch (MTB)

Cancer.gov

The Methods and Technologies Branch focuses on methods to address epidemiologic data collection, study design and analysis, and to modify technological approaches to better understand cancer susceptibility.

Multidimensional structured data visualization method and apparatus, text visualization method and apparatus, method and apparatus for visualizing and graphically navigating the world wide web, method and apparatus for visualizing hierarchies

DOEpatents

Risch, John S [Kennewick, WA; Dowson, Scott T [West Richland, WA; Hart, Michelle L [Richland, WA; Hatley, Wes L [Kennewick, WA

2008-05-13

A method of displaying correlations among information objects comprises receiving a query against a database; obtaining a query result set; and generating a visualization representing the components of the result set, the visualization including one of a plane and line to represent a data field, nodes representing data values, and links showing correlations among fields and values. Other visualization methods and apparatus are disclosed.

Multidimensional structured data visualization method and apparatus, text visualization method and apparatus, method and apparatus for visualizing and graphically navigating the world wide web, method and apparatus for visualizing hierarchies

DOEpatents

Risch, John S [Kennewick, WA; Dowson, Scott T [West Richland, WA

2012-03-06

A method of displaying correlations among information objects includes receiving a query against a database; obtaining a query result set; and generating a visualization representing the components of the result set, the visualization including one of a plane and line to represent a data field, nodes representing data values, and links showing correlations among fields and values. Other visualization methods and apparatus are disclosed.

A method for addressing differences in concentrations of fipronil and three degradates obtained by two different laboratory methods

USGS Publications Warehouse

Crawford, Charles G.; Martin, Jeffrey D.

2017-07-21

In October 2012, the U.S. Geological Survey (USGS) began measuring the concentration of the pesticide fipronil and three of its degradates (desulfinylfipronil, fipronil sulfide, and fipronil sulfone) by a new laboratory method using direct aqueous-injection liquid chromatography tandem mass spectrometry (DAI LC–MS/MS). This method replaced the previous method—in use since 2002—that used gas chromatography/mass spectrometry (GC/MS). The performance of the two methods is not comparable for fipronil and the three degradates. Concentrations of these four chemical compounds determined by the DAI LC–MS/MS method are substantially lower than the GC/MS method. A method was developed to correct for the difference in concentrations obtained by the two laboratory methods based on a methods comparison field study done in 2012. Environmental and field matrix spike samples to be analyzed by both methods from 48 stream sites from across the United States were sampled approximately three times each for this study. These data were used to develop a relation between the two laboratory methods for each compound using regression analysis. The relations were used to calibrate data obtained by the older method to the new method in order to remove any biases attributable to differences in the methods. The coefficients of the equations obtained from the regressions were used to calibrate over 16,600 observations of fipronil, as well as the three degradates determined by the GC/MS method retrieved from the USGS National Water Information System. The calibrated values were then compared to over 7,800 observations of fipronil and to the three degradates determined by the DAI LC–MS/MS method also retrieved from the National Water Information System. The original and calibrated values from the GC/MS method, along with measures of uncertainty in the calibrated values and the original values from the DAI LC–MS/MS method, are provided in an accompanying data release.

Noise source separation of diesel engine by combining binaural sound localization method and blind source separation method

NASA Astrophysics Data System (ADS)

Yao, Jiachi; Xiang, Yang; Qian, Sichong; Li, Shengyang; Wu, Shaowei

2017-11-01

In order to separate and identify the combustion noise and the piston slap noise of a diesel engine, a noise source separation and identification method that combines a binaural sound localization method and blind source separation method is proposed. During a diesel engine noise and vibration test, because a diesel engine has many complex noise sources, a lead covering method was carried out on a diesel engine to isolate other interference noise from the No. 1-5 cylinders. Only the No. 6 cylinder parts were left bare. Two microphones that simulated the human ears were utilized to measure the radiated noise signals 1 m away from the diesel engine. First, a binaural sound localization method was adopted to separate the noise sources that are in different places. Then, for noise sources that are in the same place, a blind source separation method is utilized to further separate and identify the noise sources. Finally, a coherence function method, continuous wavelet time-frequency analysis method, and prior knowledge of the diesel engine are combined to further identify the separation results. The results show that the proposed method can effectively separate and identify the combustion noise and the piston slap noise of a diesel engine. The frequency of the combustion noise and the piston slap noise are respectively concentrated at 4350 Hz and 1988 Hz. Compared with the blind source separation method, the proposed method has superior separation and identification effects, and the separation results have fewer interference components from other noise.

Method of manufacturing superconductor wire

DOEpatents

Motowidlo, Leszek

2014-09-16

A method for forming Nb.sub.3Sn superconducting wire is provided. The method employs a powder-in-tube process using a high-tin intermetallic compound, such as MnSn.sub.2, for producing the Nb.sub.3Sn. The use of a high-tin intermetallic compound enables the process to perform hot extrusion without melting the high-tin intermetallic compound. Alternatively, the method may entail drawing the wire without hot extrusion.

Methods of manipulating stressed epistructures

DOEpatents

Wanlass, Mark W

2014-04-08

A method of processing an epistructure or processing a semiconductor device including associating a conformal and flexible handle with the epistructure and removing the epistructure and handle as a unit from the parent substrate. The method further includes causing the epistructure and handle unit to conform to a shape that differs from the shape the epistructure otherwise inherently assumes upon removal from the parent substrate. A device prepared according to the disclosed methods.

A review of spectral methods

NASA Technical Reports Server (NTRS)

Lustman, L.

1984-01-01

An outline for spectral methods for partial differential equations is presented. The basic spectral algorithm is defined, collocation are emphasized and the main advantage of the method, the infinite order of accuracy in problems with smooth solutions are discussed. Examples of theoretical numerical analysis of spectral calculations are presented. An application of spectral methods to transonic flow is presented. The full potential transonic equation is among the best understood among nonlinear equations.

Methods of forming CIGS films

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mansfield, Lorelle; Ramanathan, Kannan

2017-09-19

Methods for forming CIGS films are provided. According to an aspect of the invention, a method of forming a CIGS film includes a precursor step, which includes simultaneously evaporating Cu, In, Ga, Se, and Sb onto a substrate. The Se is incident on the substrate at a rate of at least 20 .ANG./s. The method also includes a selenization step, which includes evaporating Se over the substrate after the precursor step.

Effective Methods of Teaching Moon Phases

NASA Astrophysics Data System (ADS)

Jones, Heather; Hintz, E. G.; Lawler, M. J.; Jones, M.; Mangrubang, F. R.; Neeley, J. E.

2010-01-01

This research investigates the effectiveness of several commonly used methods for teaching the causes of moon phases to sixth grade students. Common teaching methods being investigated are the use of diagrams, animations, modeling/kinesthetics and direct observations of moon phases using a planetarium. Data for each method will be measured by a pre and post assessment of students understanding of moon phases taught using one of the methods. The data will then be used to evaluate the effectiveness of each teaching method individually and comparatively, as well as the method's ability to discourage common misconceptions about moon phases. Results from this research will provide foundational data for the development of educational planetarium shows for the deaf or other linguistically disadvantage children.

Methods for environmental change; an exploratory study.

PubMed

Kok, Gerjo; Gottlieb, Nell H; Panne, Robert; Smerecnik, Chris

2012-11-28

While the interest of health promotion researchers in change methods directed at the target population has a long tradition, interest in change methods directed at the environment is still developing. In this survey, the focus is on methods for environmental change; especially about how these are composed of methods for individual change ('Bundling') and how within one environmental level, organizations, methods differ when directed at the management ('At') or applied by the management ('From'). The first part of this online survey dealt with examining the 'bundling' of individual level methods to methods at the environmental level. The question asked was to what extent the use of an environmental level method would involve the use of certain individual level methods. In the second part of the survey the question was whether there are differences between applying methods directed 'at' an organization (for instance, by a health promoter) versus 'from' within an organization itself. All of the 20 respondents are experts in the field of health promotion. Methods at the individual level are frequently bundled together as part of a method at a higher ecological level. A number of individual level methods are popular as part of most of the environmental level methods, while others are not chosen very often. Interventions directed at environmental agents often have a strong focus on the motivational part of behavior change.There are different approaches targeting a level or being targeted from a level. The health promoter will use combinations of motivation and facilitation. The manager will use individual level change methods focusing on self-efficacy and skills. Respondents think that any method may be used under the right circumstances, although few endorsed coercive methods. Taxonomies of theoretical change methods for environmental change should include combinations of individual level methods that may be bundled and separate suggestions for methods targeting a level

Detection of oral HPV infection - Comparison of two different specimen collection methods and two HPV detection methods.

PubMed

de Souza, Marjorie M A; Hartel, Gunter; Whiteman, David C; Antonsson, Annika

2018-04-01

Very little is known about the natural history of oral HPV infection. Several different methods exist to collect oral specimens and detect HPV, but their respective performance characteristics are unknown. We compared two different methods for oral specimen collection (oral saline rinse and commercial saliva kit) from 96 individuals and then analyzed the samples for HPV by two different PCR detection methods (single GP5+/6+ PCR and nested MY09/11 and GP5+/6+ PCR). For the oral rinse samples, the oral HPV prevalence was 10.4% (GP+ PCR; 10% repeatability) vs 11.5% (nested PCR method; 100% repeatability). For the commercial saliva kit samples, the prevalences were 3.1% vs 16.7% with the GP+ PCR vs the nested PCR method (repeatability 100% for both detection methods). Overall the agreement was fair or poor between samples and methods (kappa 0.06-0.36). Standardizing methods of oral sample collection and HPV detection would ensure comparability between future oral HPV studies. Copyright © 2017 Elsevier Inc. All rights reserved.

Ion binding compounds, radionuclide complexes, methods of making radionuclide complexes, methods of extracting radionuclides, and methods of delivering radionuclides to target locations

DOEpatents

Chen, Xiaoyuan; Wai, Chien M.; Fisher, Darrell R.

2000-01-01

The invention pertains to compounds for binding lanthanide ions and actinide ions. The invention further pertains to compounds for binding radionuclides, and to methods of making radionuclide complexes. Also, the invention pertains to methods of extracting radionuclides. Additionally, the invention pertains to methods of delivering radionuclides to target locations. In one aspect, the invention includes a compound comprising: a) a calix[n]arene group, wherein n is an integer greater than 3, the calix[n]arene group comprising an upper rim and a lower rim; b) at least one ionizable group attached to the lower rim; and c) an ion selected from the group consisting of lanthanide and actinide elements bound to the ionizable group. In another aspect, the invention includes a method of extracting a radionuclide, comprising: a) providing a sample comprising a radionuclide; b) providing a calix[n]arene compound in contact with the sample, wherein n is an integer greater than 3; and c) extracting radionuclide from the sample into the calix[n]arene compound. In yet another aspect, the invention includes a method of delivering a radionuclide to a target location, comprising: a) providing a calix[n]arene compound, wherein n is an integer greater than 3, the calix[n]arene compound comprising at least one ionizable group; b) providing a radionuclide bound to the calix[n]arene compound; and c) providing an antibody attached to the calix[n]arene compound, the antibody being specific for a material found at the target location.

On time discretizations for spectral methods. [numerical integration of Fourier and Chebyshev methods for dynamic partial differential equations

NASA Technical Reports Server (NTRS)

Gottlieb, D.; Turkel, E.

1980-01-01

New methods are introduced for the time integration of the Fourier and Chebyshev methods of solution for dynamic differential equations. These methods are unconditionally stable, even though no matrix inversions are required. Time steps are chosen by accuracy requirements alone. For the Fourier method both leapfrog and Runge-Kutta methods are considered. For the Chebyshev method only Runge-Kutta schemes are tested. Numerical calculations are presented to verify the analytic results. Applications to the shallow water equations are presented.

A DFFD simulation method combined with the spectral element method for solid-fluid-interaction problems

NASA Astrophysics Data System (ADS)

Chen, Li-Chieh; Huang, Mei-Jiau

2017-02-01

A 2D simulation method for a rigid body moving in an incompressible viscous fluid is proposed. It combines one of the immersed-boundary methods, the DFFD (direct forcing fictitious domain) method with the spectral element method; the former is employed for efficiently capturing the two-way FSI (fluid-structure interaction) and the geometric flexibility of the latter is utilized for any possibly co-existing stationary and complicated solid or flow boundary. A pseudo body force is imposed within the solid domain to enforce the rigid body motion and a Lagrangian mesh composed of triangular elements is employed for tracing the rigid body. In particular, a so called sub-cell scheme is proposed to smooth the discontinuity at the fluid-solid interface and to execute integrations involving Eulerian variables over the moving-solid domain. The accuracy of the proposed method is verified through an observed agreement of the simulation results of some typical flows with analytical solutions or existing literatures.

Hamiltonian methods: BRST, BFV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garcia, J. Antonio

2006-09-25

The range of applicability of Hamiltonian methods to gauge theories is very diverse and cover areas of research from phenomenology to mathematical physics. We review some of the areas developed in Mexico in the last decades. They cover the study of symplectic methods, BRST-BFV and BV approaches, Klauder projector program, and non perturbative technics used in the study of bound states in relativistic field theories.

Hamiltonian methods: BRST, BFV

NASA Astrophysics Data System (ADS)

García, J. Antonio

2006-09-01

The range of applicability of Hamiltonian methods to gauge theories is very diverse and cover areas of research from phenomenology to mathematical physics. We review some of the areas developed in México in the last decades. They cover the study of symplectic methods, BRST-BFV and BV approaches, Klauder projector program, and non perturbative technics used in the study of bound states in relativistic field theories.

Method of saccharifying cellulose

DOEpatents

Johnson, Eric A.; Demain, Arnold L.; Madia, Ashwin

1985-09-10

A method of saccharifying cellulose by incubation with the cellulase of Clostridium thermocellum in a broth containing an efficacious amount of a reducing agent. Other incubation parameters which may be advantageously controlled to stimulate saccharification include the concentration of alkaline earth salts, pH, temperature, and duration. By the method of the invention, even native crystalline cellulose such as that found in cotton may be completely saccharified.

Hazardous Waste Test Methods / SW-846

EPA Pesticide Factsheets

The Resource Conservation and Recovery Act Test Methods for Evaluating Solid Waste: Physical/Chemical Methods (SW-846) provide guidance to analytical scientists, enforcement officers and method developers across a variety of sectors.

Birth control - slow release methods

MedlinePlus

Contraception - slow-release hormonal methods; Progestin implants; Progestin injections; Skin patch; Vaginal ring ... might want to consider a different birth control method. SKIN PATCH The skin patch is placed on ...

Methods of making metal oxide nanostructures and methods of controlling morphology of same

DOEpatents

Wong, Stanislaus S; Hongjun, Zhou

2012-11-27

The present invention includes a method of producing a crystalline metal oxide nanostructure. The method comprises providing a metal salt solution and providing a basic solution; placing a porous membrane between the metal salt solution and the basic solution, wherein metal cations of the metal salt solution and hydroxide ions of the basic solution react, thereby producing a crystalline metal oxide nanostructure.

Matrix method for acoustic levitation simulation.

PubMed

Andrade, Marco A B; Perez, Nicolas; Buiochi, Flavio; Adamowski, Julio C

2011-08-01

A matrix method is presented for simulating acoustic levitators. A typical acoustic levitator consists of an ultrasonic transducer and a reflector. The matrix method is used to determine the potential for acoustic radiation force that acts on a small sphere in the standing wave field produced by the levitator. The method is based on the Rayleigh integral and it takes into account the multiple reflections that occur between the transducer and the reflector. The potential for acoustic radiation force obtained by the matrix method is validated by comparing the matrix method results with those obtained by the finite element method when using an axisymmetric model of a single-axis acoustic levitator. After validation, the method is applied in the simulation of a noncontact manipulation system consisting of two 37.9-kHz Langevin-type transducers and a plane reflector. The manipulation system allows control of the horizontal position of a small levitated sphere from -6 mm to 6 mm, which is done by changing the phase difference between the two transducers. The horizontal position of the sphere predicted by the matrix method agrees with the horizontal positions measured experimentally with a charge-coupled device camera. The main advantage of the matrix method is that it allows simulation of non-symmetric acoustic levitators without requiring much computational effort.

An investigation of the vortex method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pryor, Jr., Duaine Wright

The vortex method is a numerical scheme for solving the vorticity transport equation. Chorin introduced modern vortex methods. The vortex method is a Lagrangian, grid free method which has less intrinsic diffusion than many grid schemes. It is adaptive in the sense that elements are needed only where the vorticity is non-zero. Our description of vortex methods begins with the point vortex method of Rosenhead for two dimensional inviscid flow, and builds upon it to eventually cover the case of three dimensional slightly viscous flow with boundaries. This section gives an introduction to the fundamentals of the vortex method. Thismore » is done in order to give a basic impression of the previous work and its line of development, as well as develop some notation and concepts which will be used later. The purpose here is not to give a full review of vortex methods or the contributions made by all the researchers in the field. Please refer to the excellent review papers in Sethian and Gustafson, chapters 1 Sethian, 2 Hald, 3 Sethian, 8 Chorin provide a solid introduction to vortex methods, including convergence theory, application in two dimensions and connection to statistical mechanics and polymers. Much of the information in this review is taken from those chapters, Chorin and Marsden and Batchelor, the chapters are also useful for their extensive bibliographies.« less

Method of dehydroxylating a hydroxylated material and method of making a mesoporous film

DOEpatents

Domansky, Karel [Richland, WA; Fryxell, Glen E [Kennewick, WA; Liu, Jun [West Richland, WA; Kohler, Nathan J [Richland, WA; Baskaran, Suresh [Kennewick, WA

2002-05-07

The present invention is a method of dehydroxylating a silica surface that is hydroxylated having the steps of exposing the silica surface separately to a silicon organic compound and a dehydroxylating gas. Exposure to the silicon organic compound can be in liquid, gas or solution phase, and exposure to a dehydroxylating gas is typically at elevated temperatures. In one embodiment, the improvement of the dehydroxylation procedure is the repetition of the soaking and dehydroxylating gas exposure. In another embodiment, the improvement is the use of an inert gas that is substantially free of hydrogen. In yet another embodiment, the present invention is the combination of the two-step dehydroxylation method with a surfactant templating method of making a mesoporous film.

Method of grid generation

DOEpatents

Barnette, Daniel W.

2002-01-01

The present invention provides a method of grid generation that uses the geometry of the problem space and the governing relations to generate a grid. The method can generate a grid with minimized discretization errors, and with minimal user interaction. The method of the present invention comprises assigning grid cell locations so that, when the governing relations are discretized using the grid, at least some of the discretization errors are substantially zero. Conventional grid generation is driven by the problem space geometry; grid generation according to the present invention is driven by problem space geometry and by governing relations. The present invention accordingly can provide two significant benefits: more efficient and accurate modeling since discretization errors are minimized, and reduced cost grid generation since less human interaction is required.

Establishing a Comprehensive English Teaching Pattern Combining the Communicative Teaching Method and the Grammar-Translation Method

ERIC Educational Resources Information Center

Kong, Na

2011-01-01

Based on the current contradiction between the grammar-translation method and the communicative teaching method in English teaching, this paper, starting with clarifying the task of comprehensive English as well as the definition of the two teaching methods, objectively analyzes their advantages and disadvantages and proposes establishing a new…

Statistical Methods in Integrative Genomics

PubMed Central

Richardson, Sylvia; Tseng, George C.; Sun, Wei

2016-01-01

Statistical methods in integrative genomics aim to answer important biology questions by jointly analyzing multiple types of genomic data (vertical integration) or aggregating the same type of data across multiple studies (horizontal integration). In this article, we introduce different types of genomic data and data resources, and then review statistical methods of integrative genomics, with emphasis on the motivation and rationale of these methods. We conclude with some summary points and future research directions. PMID:27482531

Baryon interactions in lattice QCD: the direct method vs. the HAL QCD potential method

NASA Astrophysics Data System (ADS)

Iritani, T.; HAL QCD Collaboration

We make a detailed comparison between the direct method and the HAL QCD potential method for the baryon-baryon interactions, taking the $\\Xi\\Xi$ system at $m_\\pi= 0.51$ GeV in 2+1 flavor QCD and using both smeared and wall quark sources. The energy shift $\\Delta E_\\mathrm{eff}(t)$ in the direct method shows the strong dependence on the choice of quark source operators, which means that the results with either (or both) source are false. The time-dependent HAL QCD method, on the other hand, gives the quark source independent $\\Xi\\Xi$ potential, thanks to the derivative expansion of the potential, which absorbs the source dependence to the next leading order correction. The HAL QCD potential predicts the absence of the bound state in the $\\Xi\\Xi$($^1$S$_0$) channel at $m_\\pi= 0.51$ GeV, which is also confirmed by the volume dependence of finite volume energy from the potential. We also demonstrate that the origin of the fake plateau in the effective energy shift $\\Delta E_\\mathrm{eff}(t)$ at $t \\sim 1$ fm can be clarified by a few low-lying eigenfunctions and eigenvalues on the finite volume derived from the HAL QCD potential, which implies that the ground state saturation of $\\Xi\\Xi$($^1$S$_0$) requires $t \\sim 10$ fm in the direct method for the smeared source on $(4.3 \\ \\mathrm{fm})^3$ lattice, while the HAL QCD method does not suffer from such a problem.