Managing the Incompetent Teacher. Second Edition.

ERIC Educational Resources Information Center

Bridges, Edwin M.

Featuring the same practical guidelines for ridding schools of incompetent teachers as the 1984 edition, this new edition incorporates substantially revised material on three topics: criteria and information sources for evaluating teaching effectiveness, remediation procedures, and grounds for dismissal. The book presents an eight-step systematic,…

Investigating Variation, Teacher's Edition. Probing the Natural World/3.

ERIC Educational Resources Information Center

Florida State Univ., Tallahassee. Dept. of Science Education.

The teacher's edition for the unit entitled "Investigating Variation" in Intermediate Science Curriculum Study Level III, provides numerous suggestions for teaching specific activities included in the unit. The unit is aimed at selected aspects of measurement and analysis. The chapters included are "The Road…

Anthropology. Teacher Edition. Revised [and] Student Edition.

ERIC Educational Resources Information Center

Stark, Rebecca

The teacher and student editions of this book introduce students to the subject of anthropology and the subfields into which it is divided. Students learn about the beginnings of anthropology as an outgrowth of the curiosity stimulated by the Age of Exploration and how it grew into the basic field it is today. Students examine the origins and…

Biological Science: An Ecological Approach. BSCS Green Version. Teacher's Edition. Sixth Edition.

ERIC Educational Resources Information Center

Biological Sciences Curriculum Study, Colorado Springs.

This book is the teacher's edition to the 1987 edition of the Biological Sciences Curriculum Study Green Version textbook. It contains directions for teaching with this version, a description of the accompanying materials, teaching strategies by chapters, lists of useful software, safety guidelines, a materials list, chemical safety information,…

Diesel Technology: Safety Skills. Teacher Edition [and] Student Edition. Second Edition.

ERIC Educational Resources Information Center

Kellum, Mary

Teacher and student editions of this document are one in a series of competency-based instructional materials for diesel technology programs. The series aligns with the medium/heavy diesel duty truck task list used by the National Institute for Automotive Service Excellence in the certification of medium/heavy duty truck technicians. Introductory…

Physics Lab Experiments and Correlated Computer Aids. Teacher Edition.

ERIC Educational Resources Information Center

Gottlieb, Herbert H.

Forty-nine physics experiments are included in the teacher's edition of this laboratory manual. Suggestions are given in margins for preparing apparatus, organizing students, and anticipating difficulties likely to be encountered. Sample data, graphs, calculations, and sample answers to leading questions are also given for each experiment. It is…

Diesel Technology: Steering and Suspension. Second Edition. Teacher Edition [and] Student Edition.

ERIC Educational Resources Information Center

Miller, Roger; Scarberry, Terry; Tesch, Carl; Kellum, Mary

These teacher and student editions on steering and suspension are part of the diesel mechanics series of instructional materials. The series aligns with the medium/heavy duty truck task list developed by the National Automotive Technicians Education Foundation and used by the National Institute for Automotive Service Excellence in the…

Basic Science Living Skills for Today's World. Teacher's Edition.

ERIC Educational Resources Information Center

Zellers (Robert W.) Educational Services, Johnstown, PA.

This document is a teacher's edition of a basic skills curriculum in science for adult basic education (ABE) students. The course consists of 25 lessons on basic science concepts, designed to give students a good understanding of the biological and physical sciences. Suggested activities and experiments that the student can do are also included.…

Power Product Equipment Technician: Equipment Systems. Teacher Edition. Student Edition.

ERIC Educational Resources Information Center

Hilley, Robert

This packet contains teacher and student editions on the topic of equipment systems, intended for the preparation of power product equipment technicians. This publication contains seven units: (1) principles of power transmission; (2) mechanical drive systems; (3) principles of fluid power; (4) hydraulic and pneumatic drive systems; (5) wheel and…

Why You're You, Teacher's Edition. Probing the Natural World/3.

ERIC Educational Resources Information Center

Florida State Univ., Tallahassee. Dept. of Science Education.

The teacher's edition for the Intermediate Science Curriculum Study Level III unit entitled "Why You're You" provides specific suggestions for teaching the seven chapters included in the unit. The unit deals primarily with the concepts of genetics and a brief discussion is included in the beginning about some of the basic ideas in this…

Fostering Teacher Candidates' Reflective Practice through Video Editing

ERIC Educational Resources Information Center

Trent, Margaret; Gurvitch, Rachel

2015-01-01

Recently, interest in using video to promote the reflective practice in preservice teacher education has increased. Video recordings of teaching incidents inspire the reflective practice in preservice teachers by allowing them to analyze instruction and view teaching in an objective light. As an extension of video recording, video editing has…

Solving Discipline and Classroom Management Problems: Methods and Models for Today's Teachers. 6th Edition

ERIC Educational Resources Information Center

Wolfgang, Charles H.

2004-01-01

Offering a wide range of methods and practical advice, this sixth edition equips teachers with tools they need to deal effectively with a range of discipline/management problems in the classroom--from minor misbehavior to serious assaults. The following features are included in this edition: (1) A new chapter discusses how to deal with and support…

Greenhouse Management and Operations. Teacher Edition.

ERIC Educational Resources Information Center

Gowdy, Mary Ann Schwartz

This document is the teacher's edition of a module containing 16 instructional units covering competencies for students with career aspirations in horticulture. It is designed to provide high school students with an in-depth perspective of both the technical and the commercial aspects of running a greenhouse. The 16 units cover the following…

Well-Being, Teacher's Edition. Probing the Natural World/3.

ERIC Educational Resources Information Center

Florida State Univ., Tallahassee. Dept. of Science Education.

The teacher's edition for the Intermediate Science Curriculum Study Level III unit entitled "Well-Being" provides instructions for teachers. The main thrust of this unit is on examining some principles of human physiology and how these are affected by various substances. A brief introduction dealing with concepts of food, smoking,…

Comparative Critical Discourse Analysis of Student and Teacher Editions of Secondary Christian American Literature Textbooks

ERIC Educational Resources Information Center

Agiro, Christa Preston

2012-01-01

This article discusses the comparative application of critical discourse analysis to student and teacher editions of the two most widely used high school American literature textbooks by Christian publishers, examining them through the lens of critical theory. The study examined all parts of the student and teacher editions, excepting literary…

Experiencing Mathematics: Activities to Engage the High School Student. Teacher Edition

ERIC Educational Resources Information Center

Breunlin, R. James; Kasper, Timothy A.; Kolet, Michelle; Letzel, Kendra; Letzel, Thomas; Noah, John; Schutte, Jennifer; Williams, Bob; Zickert, Chris

2006-01-01

This book is the result of the collaborative effort of nine AYA National Board Certified Teachers in Mathematics. It represents a compilation of teacher-tested activities that prompt high school students to explore, conjecture and reflect on their mathematical adventures-- thus "experience mathematics." This edition will educate the teacher…

Taking the Lead: New Roles for Teachers and School-Based Coaches, 2nd Edition

ERIC Educational Resources Information Center

Killion, Joellen; Harrison, Cindy

2017-01-01

"Taking the Lead" outlines 10 practical and powerful roles for school-based coaches responsible for helping teachers increase their capacity to serve all students. The second edition is a rich update to Killion and Harrison's essential resource and includes dozens of online tools that support deep exploration and implementation of the…

Psychology Teacher's Resource Book. First Course, Third Edition.

ERIC Educational Resources Information Center

Johnson, Margo, Ed.; Wertheimer, Michael, Ed.

Now in its third edition, this book contains background materials and resources for teaching introductory high school psychology. There are 11 chapters. Textbooks appropriate for introductory courses are reviewed in the first chapter. Books of reading which are a potentially valuable source of information to both student and teacher are listed in…

Challenging Science and Literacy Activities for K-9 Students--The Cricket Chronicles. Teacher Edition

ERIC Educational Resources Information Center

Matthews, Catherine E.

2006-01-01

This book is an extensive integrated unit of study focused on that common and familiar insect--the cricket. In this edition, teachers are given a complete guide and reproducible worksheets for elementary and middle school students. With over 30 different activities on crickets, students learn science content and skills including: (1) Taxonomy; (2)…

The Effective Teacher's Guide to Autism and Communication Difficulties: Practical Strategies, Second Edition. The Effective Teacher's Guides

ERIC Educational Resources Information Center

Farrell, Michael

2011-01-01

In this welcome second edition of "The Effective Teacher's Guide to Autism and Communication Difficulties", best-selling author Michael Farrell addresses how teachers and others can develop provision for students with autism and students that have difficulties with speech, grammar, meaning, use of language and comprehension. Updated and expanded,…

Solar Energy Education. Industrial arts: teacher's guide. Field test edition. [Includes glossary

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

An instructional aid is presented which integrates the subject of solar energy into the classroom study of industrial arts. This guide for teachers was produced in addition to the student activities book for industrial arts by the USDOE Solar Energy Education. A glossary of solar energy terms is included. (BCS)

Technical Analysis of the Disruptive Behavior Rating Scale--Second Edition--Teacher Version

ERIC Educational Resources Information Center

Erford, Bradley T.; Clark, Kelly

2011-01-01

The reliability and validity of scores on the Disruptive Behavior Rating Scale-second edition-teacher version (DBRS-II-T) was analyzed. The DBRS-II-T was designed to assess teacher observations of students referred for behavioral difficulties. The five-factor model fit the data poorly, but convergent and diagnostic validities were excellent.…

Great Explorations in Mathematics: Grades 5-8. Teacher's Edition.

ERIC Educational Resources Information Center

Dyches, Richard W.; And Others

This volume is a teacher's edition in a series of books that contain open-ended exploration activities and experiments. These activities allow and encourage students to set their own goals, use their own creativity and ideas, investigate the wonders of nature, learn about the workings of real businesses, and draw conclusions from their…

Anatomy and Physiology. Module Set II: Major Body Systems. Teacher Edition [and] Student Edition. Surgical Technology.

ERIC Educational Resources Information Center

Hilley, Robert

This document, which is the second part of a two-part set of modules on anatomy and physiology for future surgical technicians, contains the teacher and student editions of an introduction to anatomy and physiology that consists of modules on the following body systems: integumentary system; skeletal system; muscular system; nervous system;…

Including Students with Special Needs: A Practical Guide for Classroom Teachers. Third Edition.

ERIC Educational Resources Information Center

Friend, Marilyn; Bursuck, William D.

This book is intended to guide teachers as they include students with special needs. The 13 chapters are: (1) "The Foundation for Educating Students with Special Needs" (e.g., issues related to inclusion); (2) "Special Education Procedures and Services" (e.g., how students obtain special services); (3) "Professional…

Primary Sources: America's Teachers on Teaching in an Era of Change. Third Edition

ERIC Educational Resources Information Center

Scholastic Inc. and the Bill & Melinda Gates Foundation, 2013

2013-01-01

This third edition of "Primary Sources" represents a joint project of Scholastic and the Bill & Melinda Gates Foundation. It reports the views of more than 20,000 public school teachers on important issues related to their profession. Fielded in July 2013, the survey asks teachers about their motivation, new learning standards,…

Aquaculture. Teacher Edition.

ERIC Educational Resources Information Center

Walker, Susan S.

This color-coded guide was developed to assist teachers in helping interested students plan, build, stock, and run aquaculture facilities of varied sizes. The guide contains 15 instructional units, each of which includes some or all of the following basic components: objective sheet, suggested activities for the teacher, instructor supplements,…

How Teachers Taught: Constancy and Change in American Classrooms, 1890-1990. Second Edition. Research on Teaching Series.

ERIC Educational Resources Information Center

Cuban, Larry

This second edition updates material in the first edition for another decade to 1990 and responds to criticisms of findings in the first edition. This book investigates teaching practices before, during, and after 20th-century reform efforts aimed at changing what teachers routinely do. Patterns of stability and change over a 100-year period are…

Anatomy and Physiology. Module Set I: Introduction to Anatomy and Physiology. Teacher Edition [and] Student Edition. Surgical Technology.

ERIC Educational Resources Information Center

Hilley, Robert

This document, which is the first part in a two-part set of modules on anatomy and physiology for future surgical technicians, contains the teacher and student editions of an introduction to anatomy and physiology that consists of modules on the following topics: (1) organization of the human body; (2) biochemistry and microbiology; (3) infection,…

Surgical Techniques. Second Edition. Teacher Edition.

ERIC Educational Resources Information Center

Bushey, Vicki; And Others

This instructor's manual contains 18 units of instruction for a course on surgical technology designed to include the entry-level competencies students need as a surgical technologist. Each unit includes some or all of the following basic components of a unit of instruction: objective sheet, suggested activities for the teacher, assignment sheets…

Beyond the Margins: Evaluating the Support for Multicultural Education within Teachers' Editions of U.S. History Textbooks

ERIC Educational Resources Information Center

Stanton, Christine Rogers

2015-01-01

Although previous research has described analysis of history textbooks in terms of multicultural education, limited attention has been given to teacher only resources, such as the "wraparound features" of teachers' editions. The study highlighted in this article applies critical discourse analysis to explore the potential for teachers'…

Human Resources Administration: A School-Based Perspective. Fourth Edition

ERIC Educational Resources Information Center

Smith, Richard

2009-01-01

Enhanced and updated, this Fourth Edition of Richard E. Smith's highly successful text examines the growing role of the principal in planning, hiring, staff development, supervision, and other human resource functions. The Fourth Edition includes new sections on ethics, induction, and the role of the mentor teacher. This edition also introduces…

Shielded Metal Arc Pipe Welding. Teacher Edition. Second Edition.

ERIC Educational Resources Information Center

Fortney, Clarence; And Others

This second edition of the shielded metal arc pipe welding curriculum guide presents both basic and advanced pipe welding skills. All specifications for procedure and welder qualification are presented according to national standards. The standards also include the test position for both groove and fillet pipe welding. The guide contains three…

The Inside Story [Learning Packages for Exploratory Career Education--7th and 8th Grades: Teacher and Student Editions.

ERIC Educational Resources Information Center

Kemp, Louie E., Comp.

The four learning packages for exploratory career education are designed for use at the seventh and eighth grade levels. Each unit includes coordinated teacher and student editions. The units are: Culinary Cubs, focusing on occupations in the areas of food management, production, and services, with special reference to dietitians; Mini Nursery,…

What Great Teachers Do Differently: Seventeen Things That Matter Most. Second Edition

ERIC Educational Resources Information Center

Whitaker, Todd

2012-01-01

In the second edition of this renowned book, you will find pearls of wisdom, heartfelt advice, and inspiration from one of the nation's leading authorities on staff motivation, teacher leadership, and principal effectiveness. With wit and understanding, Todd Whitaker describes the beliefs, behaviors, attitudes, and interactions of great teachers…

Medical and Psychosocial Problems in the Classroom: The Teacher's Role in Diagnosis and Management. Fifth Edition

ERIC Educational Resources Information Center

Haslam, Robert H. A., Ed.; Valletutti, Peter J., Ed.

2016-01-01

Now in its fifth edition, this outstanding resource for teachers and school professionals has been retitled "Medical and Psychosocial Problems in the Classroom" to more accurately reflect what teachers encounter during the course of their careers. Each chapter highlights the important role teachers play when interacting with health-care…

Mentoring New Teachers. Updated Edition.

ERIC Educational Resources Information Center

Portner, Hal

This book includes step-by-step instructions to help experienced teachers become just as skilled at mentoring beginning teachers as they are at teaching. It describes how teacher mentors can: relate to their proteges in ways that establish good working rapport; assess how the mentoring is progressing and make necessary adjustments; coach proteges…

101 "Answers" for New Teachers and Their Mentors: Effective Teaching Tips for Daily Classroom Use. Second Edition

ERIC Educational Resources Information Center

Breaux, Annette L.

2011-01-01

The 2nd edition of this bestselling title features brand new strategies plus illustrations! Make sure your new teachers are ready for the realities of the classroom. Be confident that their mentors are focused and effective. Organized so new teachers can read it by themselves, this book can also be studied collaboratively with veteran teachers who…

Power Product Equipment Technician: Lawn and Garden Equipment. Teacher Edition. Student Version.

ERIC Educational Resources Information Center

Hilley, Robert

This packet contains teacher and student editions for lawn and garden equipment repair and maintenance, intended for the preparation of power product equipment technicians. This publication contains four units: (1) introduction to lawn and garden equipment; (2) light-duty lawn and garden equipment; (3) heavy-duty lawn and garden equipment; and (4)…

Therapeutic Care. Technology Learning Activity. Teacher Edition. Technology Education Series. Level 2.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This Technology Learning Activity (TLA) for exploring therapeutic care careers is designed for use in eight class periods. It exposes students to the different types of therapeutic care and helps them understand how they can be used to treat and heal. This teacher's edition begins with an overview of technology education. The second section…

A Teacher's Guide to Including Students with Disabilities in General Physical Education, Third Edition

ERIC Educational Resources Information Center

Block, Martin E.

2007-01-01

This book, provides a comprehensive guide to making phys. ed. inclusion work for students of all ages. In this new edition of the trusted bestseller, renowned expert Martin E. Block and a select group of highly respected contributors provide: (1) new information reflecting all the latest updates to IDEA, other disability-related legislation, and…

Reading Assessment: A Primer for Teachers and Coaches. Second Edition. Solving Problems in the Teaching of Literacy

ERIC Educational Resources Information Center

Caldwell, JoAnne Schudt

2007-01-01

Now in a revised and expanded second edition, this invaluable book provides teachers and coaches with the information and tools they need to get started on the complex process of reading assessment. Grounded in a solid scientific framework, the book presents practical strategies that enable teachers to recognize "good reader" behaviors, assess…

Teaching Outside the Box: How to Grab Your Students by Their Brains, 2nd Edition

ERIC Educational Resources Information Center

Johnson, LouAnne

2011-01-01

This second edition of the bestselling book includes practical suggestions for arranging your classroom, talking to students, avoiding the misbehavior cycle, and making your school a place where students learn and teachers teach. The book also contains enlivening Q&A from teachers, letters from students, and tips for grading. This new edition has…

How Teachers Are Changing Schools. First Edition.

ERIC Educational Resources Information Center

IMPACT II--The Teachers Network, New York, NY.

The Teachers Network created The Teachers Voice Initiative to bring teachers together and empower them to create their vision of the future of education. This book presents the perspectives of participating teachers, who report on their experiences as agents of change and designers of curriculum. Papers include: "Teacher Leadership for Creating…

Diagnostic Care: Grade 9. Technology Learning Activity. Teacher Edition. Level 2. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This Technology Learning Activity (TLA) on exploring diagnostic care careers for Grade 9 is designed for use in eight class periods. It gives students experience in using standard health care equipment to perform basic diagnostic procedures. This teacher's edition begins with an overview of technology education. The second section describes…

The Chicago Handbook for Teachers: A Practical Guide to the College Classroom. Second Edition

ERIC Educational Resources Information Center

Brinkley, Alan; El-Fakahany, Esam; Dessants, Betty; Flamm, Michael; Forcey, Charles B., Jr.; Ouellett, Mathew L.; Rothschild, Eric

2011-01-01

Those who teach college students have extensive training in their disciplines, but unlike their counterparts at the high school or elementary school level, they often have surprisingly little instruction in the craft of teaching itself. "The Chicago Handbook for Teachers, Second Edition", is an extraordinarily helpful guide for anyone facing the…

Editing in Technical Communication: Theory and Practice in Editing Processes at the Graduate Level.

ERIC Educational Resources Information Center

Masse, Roger E.

At New Mexico State University, technical communication teachers have developed a course to teach editing processes to graduate students who take the advanced workshop in technical and professional communication. In this seminar group, students work on writing processes; editing processes; written, edited, and tested products; and oral processes…

Urban Teaching: The Essentials. Third Edition

ERIC Educational Resources Information Center

Weiner, Lois; Jerome, Daniel

2016-01-01

This significantly revised edition will help prospective and new city teachers navigate the realities of city teaching. Now the classic introduction to urban teaching, this book explains how global, national, state, and local reforms have impacted what teachers need to know to not only survive, but to do their jobs well. The Third Edition melds…

Probing the Natural World, Level III, Teacher's Edition: Investigating Variation. Intermediate Science Curriculum Study.

ERIC Educational Resources Information Center

Bonar, John R., Ed.; Hathway, James A., Ed.

This is the teacher's edition of one of the eight units of the Intermediate Science Curriculum Study (ISCS) for level III students (grade 9). This unit focuses on diversity in human populations, measurement, and data collection. Optional excursions are described for students who wish to study a topic in greater depth. An introduction describes…

Probing the Natural World, Level III, Teacher's Edition: Environmental Science. Intermediate Science Curriculum Study.

ERIC Educational Resources Information Center

Bonar, John R., Ed.; Hathway, James A., Ed.

This is the teacher's edition of one of the eight units of the Intermediate Science Curriculum Study (ISCS) for level III students (grade 9). This unit and its activities focuses on environmental pollution and hazards. Optional excursions are suggested for students who wish to study an area in greater depth. An introduction describes the problem…

Probing the Natural World, Level III, Teacher's Edition: Well-Being. Intermediate Science Curriculum Study.

ERIC Educational Resources Information Center

Bonar, John R., Ed.; Hathway, James A., Ed.

This is the teacher's edition of one of the eight units of the Intermediate Science Curriculum Study (ISCS) for level III students (grade 9). This unit focuses on hazards to the body from drug use. Activities are given that relate to the topic. Optional excursions are suggested for students who wish to study an area in greater depth. An…

Instructional Supervision: Applying Tools and Concepts. 2nd Edition

ERIC Educational Resources Information Center

Zepeda, Sally J.

2007-01-01

The first edition of this book was highly regarded by both professors and students for its practicality and its: (1) coverage of tools & strategies to help supervisors work effectively with teachers; (2) up-to-date approach to clinical supervision which includes teacher portfolios, action research, peer coaching, and other innovative practices;…

The Role of Unions in the American Economy. Second Edition.

ERIC Educational Resources Information Center

Marshall, Ray; Rungeling, Brian

Intended as a resource for secondary teachers, this book analyzes the role of unions in the American economy and examines the main forces influencing unions in the United States. This second edition includes important domestic and external events that have affected U.S. economic policy and unions since the first edition was published in 1976.…

Commercial and Industrial Wiring. Teacher Edition [and] Student Edition. Third Edition.

ERIC Educational Resources Information Center

Kaltwasser, Stan; Flowers, Gary; Aneke, Norbert O.

This revised curriculum guide for teachers and students includes the additional technical knowledge and applications required to help prepare students for job entry in the commercial and industrial wiring trade. The curriculum guide contains 16 units that cover the following topics: (1) blueprint reading and load calculations; (2) tools and…

Archaeology. Second Teacher Edition. Grades 5-12.

ERIC Educational Resources Information Center

Stark, Rebecca

This book includes a student edition by the same name and introduces students to various civilizations and their achievements. The self-directed activities emphasize higher-level thinking skills and activities keyed to "Bloom's Taxonomy." The table of contents lists: (1) "What Is Archaeology?"; (2) "What Is Culture?"; (3) "Where to Dig"; (4)…

Kentucky Teacher Preparation and Certification Handbook. 1983 Edition.

ERIC Educational Resources Information Center

Kentucky State Dept. of Education, Frankfort. Div. of Teacher Education and Certification.

This handbook includes teacher preparation and certification regulations adopted by the Kentucky State Board of Education through March 1983. State standards are delineated for: (1) statutory provisions relating to teacher education and certification; (2) teacher certification procedures; (3) ranking of teacher qualifications; (4) evaluation and…

Guest-Service Agent. Teacher Edition.

ERIC Educational Resources Information Center

Al-Harake, Mounzer

This teacher's guide for the hospitality and tourism industry is designed to include the entry-level competencies students will need to enter any of the occupational areas identified in the front-desk section of the lodging occupations cluster. These occupations include front-desk clerk, cashier, telephone operator, guest-service agent,…

"GFL2"! The Updated "Geography for Life: National Geography Standards, Second Edition"

ERIC Educational Resources Information Center

Heffron, Susan Gallagher

2012-01-01

"Geography for Life: National Geography Standards, Second Edition" ("GFL2") is the recently released update of the original edition published in 1994. The original edition of "Geography for Life" provided excellent guidance on geographic content for teachers, curriculum designers, publishers, and pre-service teachers as well as many other…

How to Get the Teaching Job You Want: The Complete Guide for College Graduates, Teachers Changing Schools, Returning Teachers and Career Changers. Second Edition

ERIC Educational Resources Information Center

Feirsen, Robert; Weitzman, Seth

2004-01-01

Competition for the best teaching jobs is becoming more intense. Since publication of the first edition, when it was mainly the most desirable schools that were deluged by applications, the economic climate has made the teacher market more competitive across the board, and is changing hiring practices. Now extensively revised, this book maintains…

Fundamentals of Welding. Teacher Edition.

ERIC Educational Resources Information Center

Fortney, Clarence; And Others

These instructional materials assist teachers in improving instruction on the fundamentals of welding. The following introductory information is included: use of this publication; competency profile; instructional/task analysis; related academic and workplace skills list; tools, materials, and equipment list; and 27 references. Seven units of…

The Handbook of Literacy Assessment and Evaluation. Second Edition.

ERIC Educational Resources Information Center

Harp, Bill

This handbook gives teachers, reading specialists, administrators, or students concise, up-to-date information on the most popular assessment and evaluation tools in literacy. This second edition retains many of the tools reviewed in the first edition and adds 12 new tools. The first section reviews 24 tools that are teacher-made. The second…

Requirements for Certification for Elementary Schools, Secondary Schools, Junior Colleges: Teachers, Counselors, Librarians, Administrators. Forty-Ninth Edition, 1984-85.

ERIC Educational Resources Information Center

Burks, Mary P.

This edition of "Requirements for Certification" updates pertinent information on certification requirements for teachers, administrators, librarians, counselors, and other school personnel in each state in the United States. Outlines are provided of recommendations on certification by the following regional and national associations: Middle…

Medical-Surgical II. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This publication is designed to provide students with the knowledge they need to pursue a career in medical-surgical nursing. Fifteen units are provided. Each instructional unit includes some or all of the basic components of a unit of instruction: performance objectives, suggested activities for the teacher, information sheets, job sheets,…

Medical-Surgical I. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This publication is designed to provide students with the knowledge they need to pursue a career in medical-surgical nursing. Eight units are provided. Each instructional unit includes some or all of the basic components of a unit of instruction: performance objectives, suggested activities for the teacher, information sheets, job sheets, written…

Food Production, Management and Services: Service. Teacher Edition. Second Edition.

ERIC Educational Resources Information Center

Palan, Earl

This food production, management, and services teacher guide contains nine units: (1) orientation; (2) types of service; (3) table settings; (4) dining room personnel; (5) dining room procedures; (6) side work; (7) guest/employee relationships; (8) sales techniques; and (9) safety and sanitation. Suggestions are included to increase reinforcement…

Food Production, Management, and Services. Production. Teacher Edition. Second Edition.

ERIC Educational Resources Information Center

Gibson, LeRoy

This teacher's guide contains 20 units of instruction for a course in production in the food production, management, and services area. Units of instruction are designed for use in more than one lesson or class period of instruction. Introductory materials include the following: a competency profile; instructional/task analysis; related academic…

Aquaculture. Second Edition. Teacher Edition.

ERIC Educational Resources Information Center

Walker, Susan S.; Crummett, Dan

This teacher and student guide for aquaculture contains 15 units of instruction that cover the following topics: (1) introduction to aquaculture; (2) the aquatic environment; (3) fundamental fish biology; (4) marketing; (5) site selection; (6) facility design and layout; (7) water quality management; (8) fish health management; (9) commercial…

A Vector Approach to Euclidean Geometry: Inner Product Spaces, Euclidean Geometry and Trigonometry, Volume 2. Teacher's Edition.

ERIC Educational Resources Information Center

Vaughan, Herbert E.; Szabo, Steven

This is the teacher's edition of a text for the second year of a two-year high school geometry course. The course bases plane and solid geometry and trigonometry on the fact that the translations of a Euclidean space constitute a vector space which has an inner product. Congruence is a geometric topic reserved for Volume 2. Volume 2 opens with an…

Safety in Science for Primary Schools. 1st Edition.

ERIC Educational Resources Information Center

Association for Science Education, Cambridge (England).

This packet of teacher education materials is based on the publication "Be Safe!" and is intended for those teaching science to children ages 4 to 12. The pack contains INSET materials that supplement a safety exhibition contained in the second edition of "Be Safe!." Five basic activities include instructions for training…

Requirements for Certification [of] Teachers, Counselors, Librarians, Administrators for Elementary Schools, Secondary Schools, Junior Colleges. Forty-eighth Edition, 1983-84.

ERIC Educational Resources Information Center

Woellner, Elizabeth H.

This edition of "Requirements for Certification" updates pertinent information on certification requirements for teachers, administrators, librarians, counselors, and other school personnel in each state in the United States. Outlines are provided of recommendations on certification by regional and national associations, and sources of information…

The Story of California. Student Workbook. Teacher's Edition = Libro de Trabajo de La Historia de California. Edicion del Maestro.

ERIC Educational Resources Information Center

Gray (Naomi) Associates, Inc., San Francisco, CA.

The workbook is designed to accompany a textbook, "The Story of California," a Spanish-English bilingual history and geography of the state intended for classroom use by limited-English-proficient, native Spanish-speaking students in California's urban middle schools. The teacher's edition, presented here, consists of reproductions of 51…

Basic Facialist. Teacher Edition. Cosmetology Series.

ERIC Educational Resources Information Center

Rogers, Jeanette A.

This Oklahoma curriculum guide contains six units. Each instructional unit includes some or all of these basic components: performance objectives; suggested activities for the teacher; pretest; handouts; information sheets; transparency masters; assignment sheets; job sheets; practical tests; written tests; and answers to pretest, assignment…

ACR Electrical Systems. Teacher Edition [and] Student Edition.

ERIC Educational Resources Information Center

Clemons, Mark

This document contains a teacher's guide and student guide for a high school-level competency-based course in air conditioning and refrigeration (ACR) equipment electrical systems. Presented in the teacher's guide are the following: explanation of the instructional units' use; competency profile for recording students' performance of the tasks in…

Projections of Education Statistics to 2018. Thirty-Seventh Edition. NCES 2009-062

ERIC Educational Resources Information Center

Hussar, William J.; Bailey, Tabitha M.

2009-01-01

"Projections of Education Statistics to 2018" is the 37th report in a series begun in 1964. It includes statistics on elementary and secondary schools and degree-granting institutions. Included are projections of enrollment, graduates, teachers, and expenditures to the year 2018. This is the first edition of the "Projections of…

Basics of Desktop Publishing. Teacher Edition.

ERIC Educational Resources Information Center

Beeby, Ellen

This color-coded teacher's guide contains curriculum materials designed to give students an awareness of various desktop publishing techniques before they determine their computer hardware and software needs. The guide contains six units, each of which includes some or all of the following basic components: objective sheet, suggested activities…

Basics of Desktop Publishing. Second Edition.

ERIC Educational Resources Information Center

Beeby, Ellen; Crummett, Jerrie

This document contains teacher and student materials for a basic course in desktop publishing. Six units of instruction cover the following: (1) introduction to desktop publishing; (2) desktop publishing systems; (3) software; (4) type selection; (5) document design; and (6) layout. The teacher edition contains some or all of the following…

Audiovisual Materials for Teaching Economics. Third Edition.

ERIC Educational Resources Information Center

Harter, Charlotte T.; And Others

The third edition of this catalog, which expands and revises earlier editions, annotates audiovisual items for economic education in kindergarten through college. The purpose of the catalog is to help teachers select sound economic materials for classroom use. A selective listing, the catalog cites over 700 items out of more than 1200 items…

Introduction to Natural Resources. Teacher Edition.

ERIC Educational Resources Information Center

Hehn, Darold; Newport, Bob

This color-coded teacher's guide contains curriculum materials designed to help students develop an awareness of renewable and nonrenewable natural resources and to identify occupations in the area of natural resources. The guide contains nine units, each of which includes some or all of the following basic components: objective sheet, suggested…

Technology for Teachers. 6th Edition.

ERIC Educational Resources Information Center

Volker, Roger; Simonson, Michael

This book helps teachers learn how to use and make educational media, covering traditional and new media such as computer laboratories, authentic assessment, theory bases, and hypermedia. Chapter topics progress from simple to complex. Each chapter includes clearly stated behavioral objectives that provide a study guide for students and can serve…

Mechanical Drafting with CAD. Teacher Edition.

ERIC Educational Resources Information Center

McClain, Gerald R.

This instructor's manual contains 13 units of instruction for a course on mechanical drafting with options for using computer-aided drafting (CAD). Each unit includes some or all of the following basic components of a unit of instruction: objective sheet, suggested activities for the teacher, assignment sheets and answers to assignment sheets,…

GREENHOUSE WORKER, TEACHERS COPY.

ERIC Educational Resources Information Center

FITTS, JAMES; JOHNSON, JOHNNY

DESIGNED FOR VOCATIONAL AGRICULTURE STUDENTS IN A COOPERATIVE PART-TIME TRAINING PROGRAM, THIS GUIDE WAS DEVELOPED BY TWO VOCATIONAL AGRICULTURE TEACHERS WITH INTEREST, TRAINING, AND EXPERIENCE IN HORTICULTURE AND WAS COORDINATED AND EDITED BY A SUBJECT MATTER SPECIALIST. INCLUDED ARE TEN UNITS, EACH DIVIDED INTO TOPICS. EACH TOPIC INCLUDES A…

Surgical Procedures. Second Edition. Teacher Edition.

ERIC Educational Resources Information Center

Baker, Beverly; And Others

This teacher's guide contains 13 units of instruction for a course that will prepare students with the entry-level competencies needed by a surgical technologist. The course covers the following topics: introduction to surgical procedures; diagnostic procedures; general surgery; gastrointestinal surgery; obstetrics and gynecological surgery;…

Tape It Yourself: Videotapes for Teacher Education

ERIC Educational Resources Information Center

Ebsworth, Miriam Eistein; Feknous, Barbara; Loyet, Dianne; Zimmerman, Spencer

2004-01-01

This paper describes the development and implementation of a series of videotapes of ESL classes for a pre-service teacher education program grounded in experiential learning theory. The videos included footage of ESL classrooms, and tapes edited and supplemented with interviews of ESL teachers. Our experience demonstrates that-with relatively low…

An Economic Course for Elementary School Teachers. Second Revised Edition.

ERIC Educational Resources Information Center

Lovell, Hugh; Harter, Charlotte

This handbook is intended to help economic educators develop teacher training courses for demonstrating to classroom teachers how to teach economics to children, grades 1-9. Teachers enrolled in the course carry out their own pupil activities which teach economic ideas. These activities include problem solving, case studies, skits, making posters,…

Teacher Quality Toolkit. 2nd Edition

ERIC Educational Resources Information Center

Lauer, Patricia A.; Dean, Ceri B.; Martin-Glenn, Mya L.; Asensio, Margaret L.

2005-01-01

The Teacher Quality Toolkit addresses the continuum of teacher learning by providing tools that can be used to improve both preservice, and inservice teacher education. Each chapter provides self assessment tools that can guide progress toward improved teacher quality and describes resources for designing exemplary programs and practices. Chapters…

Adult and Family Living. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This curriculum guide for teachers is designed for use with 11th- and 12th-grade students who have had no more than 1 year of vocational home economics. It focuses on providing young adults with the knowledge and skills they need for healthy and positive adult and family lives. It includes 27 units in 8 sections as follows: (1) personal…

An analysis of teacher’s preparation in implementing 2013 revision edition curriculum on mathematics specialization learning

NASA Astrophysics Data System (ADS)

Susilo, T.; Suryawan, A.

2018-05-01

This study aimed to determine the pedagogical competence of teachers, the readiness of planning and implementation of learning related to the implementation 2013 revised edition curriculum on mathematics specialization learning for senior high schools Wonogiri. Informants in this study there are 6 high school mathematics teachers X and XI class who teach in the school district Wonogiri. Data were collected using questionnaire method, interview, observation and documentation. Qualitative data analysis is done interactively through 4 paths: data collection, data reduction, data display, drawing conclusion. The results showed that high school mathematics teacher class X and XI in school district of Wonogiri City. The results show that most high school mathematics teachers in grade X and XI are ready to implement the 2013 revised edition curriculum and a few have not been able to implement due to internal or external factors. High school math teachers at Wonogiri district who are ready to face the 2013 revised edition curriculum have applied 10 teacher pedagogic competency indicators according to Regulation of the national education ministry Number 16 Year 2007 in learning. The readiness and implementation of mathematics learning is in line with the demands of the 2013 revised edition curriculum. Based on the teachers who are not ready, data on issues that arise in the implementation of the 2013 revised edition curriculum. Especially the problems in learning, namely mismatch of Core Competence (KI) and Basic Competence (KD) in teacher manual, material disregard in student handbook and lack of examples of problems that exist in teacher manual.

"Convenience Editors" as Legitimate Participants in the Practice of Scientific Editing: An Interview Study

ERIC Educational Resources Information Center

Willey, Ian; Tanimoto, Kimie

2013-01-01

Native-English-speaking English teachers at universities in EFL contexts are often asked to edit scientific manuscripts written by English as an additional language (EAL) colleagues. However, a lack of familiarity with scientific writing can make such editing tasks burdensome to English teachers. Using Lave and Wenger's (1991) notion of legitimate…

The Economy of Energy Conservation in Educational Facilities. A Report. Revised Edition.

ERIC Educational Resources Information Center

Educational Facilities Labs., Inc., New York, NY.

This is an update of the 1973 edition of a guide for energy conservation in schools. This Educational Facilities Laboratories publication is an information source for teachers, school administrators, school maintenance personnel, school designers, or anyone interested in conserving energy in schools. Topics discussed include: (1) life-cycle…

Residential Wiring. Teacher Edition [and] Student Edition. Third Edition.

ERIC Educational Resources Information Center

Taylor, Mark; Batson, Larry; Carroll, Charles; Ipock, Dan; Leak, Lester; Onstott, Todd

This revised curriculum guide for teachers and students is designed to help prepare students for entry-level employment in the residential wiring trade. The curriculum guide contains six units that cover the following topics: (1) blueprint reading and load calculations; (2) service; (3) rough-in; (4) trim out and troubleshooting; (5) low voltage…

Measurement and Assessment in Teaching. Eighth Edition.

ERIC Educational Resources Information Center

Linn, Robert L.; Gronlund, Norman E.

This book is intended to introduce the classroom teacher and prospective teacher to the elements of measurement and assessment that are essential to good teaching. The main theme is that assessment plays an important role in the instructional process. This edition has been revised to reflect major changes in educational assessment since the last…

Kaleidoscope: A Multicultural Booklist for Grades K-8. Third Edition. NCTE Bibliography Series.

ERIC Educational Resources Information Center

Yokota, Junko, Ed.

The third edition of this annotated bibliography collection offers students, teachers, and librarians a helpful guide to the best multicultural literature (published between 1996 and 1998) for elementary and middle school readers. With approximately 600 annotations on topics and formats including picture story books, realistic fiction, history and…

New Teachers Handbook. Second Edition.

ERIC Educational Resources Information Center

IMPACT II--The Teachers Network, New York, NY.

This practical guide for new teachers is written by teachers and offers strategies for the early years of teaching that cover classroom practice and professional development. Seven chapters address teaching practice and cover the following topics: getting to know students at the beginning of the year; strategic planning for the whole year;…

Introduction to Hospitality and Tourism. Teacher Edition.

ERIC Educational Resources Information Center

Walker, Susan S.

This teacher's guide is the core publication of a series of instructional materials developed for the hospitality and tourism industry. It includes the entry-level competencies students will need to enter any of the occupational areas identified in the four cluster areas of the hospitality and tourism industry: lodging, food service, travel and…

What Successful Science Teachers Do: 75 Research-Based Strategies

ERIC Educational Resources Information Center

Glasgow, Neal A.; Cheyne, Michele; Yerrick, Randy K.

2010-01-01

The experience and science expertise of these award-winning authors makes this easy-to-use guide a teacher's treasure trove. This latest edition to the popular What Successful Teachers Do series describes 75 research-based strategies and outlines best practices for inquiry-oriented science. Each strategy includes a brief description of the…

Matematicas en la vida actual. Volumen II, edicion para el maestro. (Mathematics: A Practical View. Volume II, Teacher Edition). Applied Basic Curriculum Series.

ERIC Educational Resources Information Center

Evaluation, Dissemination and Assessment Center, Dallas.

This Spanish language teacher's edition of a practical mathematics text for the intermediate grades contains three components which can be structured in different combinations according to different student needs. Built around a review of selected objectives in the mathematics basic curriculum, the material is intended to stimulate interest in…

Matematicas en la vida actual. Volumen I, edicion para el maestro. (Mathematics: A Practical View. Volume I, Teacher Edition). Applied Basic Curriculum Series.

ERIC Educational Resources Information Center

Evaluation, Dissemination and Assessment Center, Dallas.

This Spanish language teacher's edition of a practical mathematics text for the intermediate grades contains three components which can be structured in different combinations according to different student needs. Built around a review of selected objectives in the mathematics basic curriculum, the material is intended to stimulate interest in…

Matematicas en la vida actual. Volumen III, edicion para el maestro. (Mathematics: A Practical View. Volume III, Teacher Edition). Applied Basic Curriculum Series.

ERIC Educational Resources Information Center

Evaluation, Dissemination and Assessment Center, Dallas.

This Spanish language teacher's edition of a practical mathematics text for the intermediate grades contains three components which can be structured in different combinations according to different student needs. Built around a review of selected objectives in the mathematics basic curriculum, the material is intended to stimulate interest in…

Employment in Agribusiness. Teacher Edition. Second Edition.

ERIC Educational Resources Information Center

Crummett, Dan M.; Newport, Alan K.

This curriculum guide is designed to help teachers prepare students with the variety of skills that will help them obtain jobs that can turn into rewarding careers in agribusiness. The guide also serves as a resource for students participating in agricultural sales and service competitions sponsored by student organizations such as Future Farmers…

Primary Sources. Update: Teachers' Views on Common Core State Standards

ERIC Educational Resources Information Center

Scholastic Inc. and the Bill & Melinda Gates Foundation, 2014

2014-01-01

Scholastic and the Bill & Melinda Gates Foundation fielded the third edition of the "Primary Sources" survey of America's teachers in July 2013 (see ED562664). Twenty thousand pre-K through grade 12 public school teachers responded, sharing their perspectives on issues important to their profession, including the Common Core State…

Peer-Editing Practice in the Writing Classroom: Benefits and Drawbacks

ERIC Educational Resources Information Center

Deni, Ann Rosnida Md.; Zainal, Zainor Izat

2011-01-01

Small scale studies have shown that peer-editing is beneficial to students as it increases their awareness of the complex process of writing, it improves their knowledge of and skills in writing and helps them become more autonomous in learning. Teachers too may benefit from peer-editing as this practice discloses invaluable information on…

Modern Indian Psychology. Revised Edition.

ERIC Educational Resources Information Center

Bryde, John F.

Written on the basis of senior Indian verbal relatings collected over a 23-year span, this revised edition on modern Indian psychology incorporates suggestions from Indian students and their teachers, Indian and non-Indian social studies experts, and other Indian people. The book contains 6 major divisions: (1) "Culture and Indian…

Impact of Technology on the Family. Teacher Edition.

ERIC Educational Resources Information Center

Mid-America Vocational Curriculum Consortium, Stillwater, OK.

These instructional materials create an awareness of new technological innovations and how they affect personal and family life. This teacher's guide is for instructing secondary students enrolled in a home economics program. The following introductory information is included: use of this publication, competency profile, instructional/task…

The Principal as Instructional Leader: A Practical Handbook. 3rd Edition

ERIC Educational Resources Information Center

Zepeda, Sally J.

2013-01-01

In the updated third edition of this highly successful book, leadership expert, Sally Zepeda offers savvy advice to both new and seasoned principals and assistant principals. You get practical tools and strategies, along with real-world examples to help you improve teacher effectiveness and boost student achievement. This edition features valuable…

Book Review: New Perspectives on Technical Editing

NASA Astrophysics Data System (ADS)

Murphy, A. J. (Ed.); Sterken, Christiaan

2012-08-01

New Perspectives on Technical Editing by Avon J. Murphy (ed.) ISBN : 978-0895033949 (2010) Baywood Publishing Company Inc, Hardcover, 210 pages, 35.5 GBP This book presents a collection of 10 chapters dealing with diverse aspects of technical editing (ie, editorial planning, and analysis and structural changes made to other people's technological documents): research in technical editing, trends and teaching of technical editing, copyediting, and technical journal editing. The role and function of the modern journal and book editor is also dealt with in detail. Each chapter is written by an expert in the field: senior editors, university professors in technical communication, technical writers and linguists. The ever-evolving role of the editor is clearly elucidated in several historical reviews, and in the descriptions of the expectations for the future. A very striking aspect of this book is its extensive collection of bibliographic resources: every chapter lists dozens of very useful references, and the closing chapter, and annotated bibliography, contain many not so well known references, and are most useful. All in all, the book is a treasure trove listing more than 400 references, in addition to numerous webpage URLs embedded in the texts. The book is designed to help the reader to understand current practices and norms in technical editing, and to help to take action in editing as well as in teaching and educating would-be editors. The audience for this book thus includes editors and teachers, but also writers, researchers and students. A deep reading of this book will result in a better understanding of the difference between full technical editing and its much narrower component so well known as copyediting, and will convince any prospective editor that editing should not be undertaken if the people involved do not master the art of precision and accuracy in technical (as well as in human) communication, do not possess the technical know how and computer

Promoting School Success. Third Edition

ERIC Educational Resources Information Center

Lovitt, Thomas C.

2007-01-01

Like its two predecessors, "Preventing School Dropouts" [C1991] and "Preventing School Failure" [C2000], this third edition is a book about teaching. Although primarily written for teachers, tutors and parents may also find this book helpful. It is a collection of carefully selected teaching techniques aimed at helping young adults learn important…

Teacher candidates' beliefs about including socioscientific issues in physics and chemistry

NASA Astrophysics Data System (ADS)

Barrett, Sarah Elizabeth

Teaching science for social justice involves a deliberate effort to reconstruct society into something more equitable and just. Introducing socioscientific issues (SSI) into science is one strategy toward this end. However, research indicates that SSI are rarely discussed in the physical sciences even though they exist. This may be due to the beliefs of chemistry and physics teachers with respect to what belongs in these subjects. If we wish to begin to influence these beliefs through initial teacher education, it is essential for teacher educators to understand the origins of these beliefs. In this qualitative study 12 teacher candidates were interviewed at 3 points during a 9 month teacher education program: at the beginning of the course (in September), after the first practicum (in November) and after the second practicum (in March). Teacher candidates' beliefs did not change significantly from the beginning of the study to the end. They displayed varying degrees of commitment to including SSI in their teaching. Based on their (a) conception of the ethics of science, (b) goals for science education, (c) idea of the place of ethics in science (education), and (d) beliefs about including SSI, the teacher candidates were divided into four groups. Four archetypes were derived: "Model Scientist/Engineer", "Model Individual", "Model Teacher", and "Model Citizen". Since these groups are archetypes, none of the participants fits into the categories perfectly but individual teacher candidates demonstrated more characteristics of one archetype than others. Only the 3 Model Citizens were committed to including SSI in their teaching while the others placed the priority on preparing students for the next level of schooling. A model was developed to serve as a microgeneology of teacher candidates' beliefs about including SSI in their teaching. It traced their beliefs from (a) life experiences to (b) conception of ethics and nature of science to (c) goals for science

Inventory America: Residential Buildings. Student Workbook, Pilot Edition; Teacher & Project Supervisor Manual, Pilot Edition.

ERIC Educational Resources Information Center

Haupt, Richard; Pomeroy, Robert W., Ed.

Designed as a special studies unit for secondary school students or for adult volunteers, this student workbook and teacher's guide explains how to produce an accurate record of memorable neighborhood houses. The activities in the workbook include observation and information gathering. The workbook sections describe various steps in the process…

Process Instrumentation. Teacher Edition.

ERIC Educational Resources Information Center

Brown, A. O., III; Fowler, Malcolm

This module provides instructional materials that are designed to help teachers train students in job skills for entry-level jobs as instrumentation technicians. This text addresses the basics of troubleshooting control loops, and the transducers, transmitters, signal conditioners, control valves, and controllers that enable process systems to…

State Teacher Policy Yearbook: Progress on Teacher Quality, 2007. Colorado State Summary

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2007

2007-01-01

The "State Teacher Policy Yearbook" examines what is arguably the single most powerful authority over the teaching profession: state government. This Colorado edition of the National Council on Teacher Quality's (NCTQ's) "State Teacher Policy Yearbook" is the first of what will be an annual look at the status of state policies…

On Being a "Scholarly" Teacher

ERIC Educational Resources Information Center

Prenkert, Jamie Darin

2013-01-01

In this article, the author shares his thoughts on being a "scholarly" teacher. He points out that engaging in scholarly activity, which includes publishing as well as other ways to engage with relevant research, like reviewing and editing for journals, can lead to better teaching. This sort of scholarly commitment allows an instructor to maintain…

Places Where Teachers Are Taught. First Edition.

ERIC Educational Resources Information Center

Goodlad, John I., Ed.; And Others

This book utilizes 29 case histories of geographically and institutionally diverse teacher education programs to provide a comprehensive historical perspective on teacher education in the United States. The volume, organized into four parts, is further divided into nine chapters. "Part One: "Teacher Education: A Contemporary Perspective…

Teacher Evaluation That Works!! Second Edition

ERIC Educational Resources Information Center

Ribas, William B.

2005-01-01

Creating a system for successfully supervising and evaluating the entire teaching staff of a school district is a daunting task. An effective system-wide program can only be achieved if the administrators, teachers and the teachers' association understand and attend to the educational, legal, public relations (political), and social-emotional…

Motorcycle Mechanic. Teacher Edition.

ERIC Educational Resources Information Center

Baugus, Mickey; Fulkerson, Dan, Ed.

These teacher's materials are for a 19-unit competency-based course on entry-level motorcycle mechanics at the secondary and postsecondary levels. The 19 units are: (1) introduction to motorcycle repair; (2) general safety; (3) tools and equipment; (4) metric measurements; (5) fasteners; (6) service department operations; (7) motorcycle engines;…

Snowmobile Repair. Teacher Edition.

ERIC Educational Resources Information Center

Hennessy, Stephen S.; Conrad, Rex

This teacher's guide contains 14 units on snowmobile repair: (1) introduction to snowmobile repair; (2) skis, front suspension, and steering; (3) drive clutch; (4) drive belts; (5) driven clutch; (6) chain drives; (7) jackshafts and axles; (8) rear suspension; (9) tracks; (10) shock absorbers; (11) brakes; (12) engines; (13) ignition and…

Controlled flexibility in technical editing - The levels-of-edit concept at JPL

NASA Technical Reports Server (NTRS)

Buehler, M. F.

1977-01-01

The levels-of-edit concept, which can be used to specify the amount of editorial effort involved in the preparation of a manuscript for publication, is discussed. Nine types of editing are identified and described. These include coordination edit (preparing estimates, gathering cost data, monitoring production processes), policy edit, integrity edit (making sure that parts of a publication match in a physical or numerical sense), screening edit (ensuring that the quality of camera-ready copy is sufficient for external publication), copy clarification edit, format edit, mechanical style edit, language edit, and substantive edit (reviewing the manuscript for content coherence, emphasis, subordination and parallelism). These functions are grouped into five levels of edit. An edit-level number is assigned to each manuscript, providing a quantitative and qualitative indicator of the editing to be done which is clearly understood by authors, managers, and editors alike. In addition, clear boundaries are drawn between normal and extraordinary editing tasks. Individual organizations will group various edits in different ways to reflect their needs and priorities; the essential element of the system is unambiguous definition and coding of the types and amount of work to be done.

The Newbery and Caldecott Awards: A Guide to the Medal and Honor Books. 2012 Edition

ERIC Educational Resources Information Center

ALA Editions, 2012

2012-01-01

Updated to include the 2012 award and honor books, this new edition of the annual guide to the Newbery and Caldecott awards gathers together the books deemed most distinguished in American children's literature and illustration since the inception of the renowned prizes. Librarians and teachers everywhere rely on this guidebook for quick reference…

The Teacher and Integration. Revised Edition.

ERIC Educational Resources Information Center

Noar, Gertrude

This book is intended for both beginning and experienced teachers who face many difficult challenges in today's desegregated school. Teachers must come to feel and recognize the many contingencies of the desegregated classroom if it is to be a place for learning. Because social class segregates children as often as does race, the major question…

2014 Teacher Prep Review: A Review of the Nation's Teacher Preparation Programs

ERIC Educational Resources Information Center

Greenberg, Julie; Walsh, Kate; McKee, Arthur

2014-01-01

"Teacher Prep Review 2014" is the second edition of the National Council on Teacher Quality's (NCTQ's) annual assessment of the nation's 2,400 teacher prep programs. The "Review" uncovers early evidence that teacher prep programs are beginning to make changes. It arrives at a time of heightened, unprecedented…

Student, teacher, and classroom predictors of between-teacher variance of students' teacher-rated behavior.

PubMed

Splett, Joni W; Smith-Millman, Marissa; Raborn, Anthony; Brann, Kristy L; Flaspohler, Paul D; Maras, Melissa A

2018-03-08

The current study examined between-teacher variance in teacher ratings of student behavioral and emotional risk to identify student, teacher and classroom characteristics that predict such differences and can be considered in future research and practice. Data were taken from seven elementary schools in one school district implementing universal screening, including 1,241 students rated by 68 teachers. Students were mostly African America (68.5%) with equal gender (female 50.1%) and grade-level distributions. Teachers, mostly White (76.5%) and female (89.7%), completed both a background survey regarding their professional experiences and demographic characteristics and the Behavior Assessment System for Children (Second Edition) Behavioral and Emotional Screening System-Teacher Form for all students in their class, rating an average of 17.69 students each. Extant student data were provided by the district. Analyses followed multilevel linear model stepwise model-building procedures. We detected a significant amount of variance in teachers' ratings of students' behavioral and emotional risk at both student and teacher/classroom levels with student predictors explaining about 39% of student-level variance and teacher/classroom predictors explaining about 20% of between-teacher differences. The final model fit the data (Akaike information criterion = 8,687.709; pseudo-R2 = 0.544) significantly better than the null model (Akaike information criterion = 9,457.160). Significant predictors included student gender, race ethnicity, academic performance and disciplinary incidents, teacher gender, student-teacher gender interaction, teacher professional development in behavior screening, and classroom academic performance. Future research and practice should interpret teacher-rated universal screening of students' behavioral and emotional risk with consideration of the between-teacher variance unrelated to student behavior detected. (PsycINFO Database Record (c) 2018 APA, all

State Teacher Policy Yearbook: Progress on Teacher Quality, 2007. New Jersey State Summary

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2007

2007-01-01

The "State Teacher Policy Yearbook" examines what is arguably the single most powerful authority over the teaching profession: state government. This New Jersey edition of the National Council on Teacher Quality's (NCTQ's) "State Teacher Policy Yearbook" is the first of what will be an annual look at the status of state…

State Teacher Policy Yearbook: Progress on Teacher Quality, 2007. New Mexico State Summary

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2007

2007-01-01

The "State Teacher Policy Yearbook" examines what is arguably the single most powerful authority over the teaching profession: state government. This New Mexico edition of the National Council on Teacher Quality's (NCTQ's) "State Teacher Policy Yearbook" is the first of what will be an annual look at the status of state…

State Teacher Policy Yearbook: Progress on Teacher Quality, 2007. New Hampshire State Summary

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2007

2007-01-01

The "State Teacher Policy Yearbook" examines what is arguably the single most powerful authority over the teaching profession: state government. This New Hampshire edition of the National Council on Teacher Quality's (NCTQ's) "State Teacher Policy Yearbook" is the first of what will be an annual look at the status of state…

Noise Pollution, Teachers' Edition.

ERIC Educational Resources Information Center

O'Donnell, Patrick A.; Lavaroni, Charles W.

One of three in a series about pollution, this teacher's guide for a unit on noise pollution is designed for use in junior high school grades. It offers suggestions for extending the information and activities contained in the textual material for students. Chapter 1 discusses the problem of noise pollution and involves students in processes of…

Water Pollution, Teachers' Edition.

ERIC Educational Resources Information Center

Lavaroni, Charles W.; And Others

One of three in a series about pollution, this teacher's guide for a unit on water pollution is designed for use in junior high school grades. It offers suggestions for extending the information and activities contained in the textual material for students. Chapter 1 discusses the problem of water pollution and involves students in processes of…

Kentucky Teacher Preparation and Certification Handbook. 1981 Edition.

ERIC Educational Resources Information Center

Kentucky State Dept. of Education, Frankfort.

This handbook sets forth the regulations of the Kentucky State Board of Education that relate to teacher education and certification. The following topics are covered: (1) selected statutory provisions relating to teacher education and certification; (2) teacher certification procedures; (3) ranking of teacher qualifications; (4) procedures for…

Environments. Basic Edition. Science for Micronesia.

ERIC Educational Resources Information Center

Trust Territory of the Pacific Islands Dept. of Education, Saipan.

Presented is a teacher's guide to an elementary science unit designed for use with fourth grade, or higher, students in the Trust Territory of Micronesia. Although there is a degree of similarity to curriculum materials developed for the Science Curriculum Improvement Study, this Micronesian unit does not purport to be an adaption or edition of…

Populations. Basic Edition. Science for Micronesia.

ERIC Educational Resources Information Center

Trust Territory of the Pacific Islands Dept. of Education, Saipan.

This teacher's guide is for an elementary school science unit designed for use with third grade (or older) children in the Trust Territory of Micronesia. Although there is a degree of similarity to curriculum materials developed for the Science Curriculum Improvement Study, this Micronesian unit does not purport to be an adaptation or edition of…

Adolescents at School: Perspectives on Youth, Identity, and Education. Second Edition

ERIC Educational Resources Information Center

Sadowski, Michael, Ed.

2008-01-01

As any teacher or parent knows, adolescence is a time when youth grapple with the question, "Who am I?" Issues of race, ethnicity, class, gender, sexual orientation, and ability can complicate this question for young people, affecting their schoolwork and their relationships with teachers, family, and peers. This new edition of "Adolescents at…

Abundant off-target edits from site-directed RNA editing can be reduced by nuclear localization of the editing enzyme.

PubMed

Vallecillo-Viejo, Isabel C; Liscovitch-Brauer, Noa; Montiel-Gonzalez, Maria Fernanda; Eisenberg, Eli; Rosenthal, Joshua J C

2018-01-02

Site-directed RNA editing (SDRE) is a general strategy for making targeted base changes in RNA molecules. Although the approach is relatively new, several groups, including our own, have been working on its development. The basic strategy has been to couple the catalytic domain of an adenosine (A) to inosine (I) RNA editing enzyme to a guide RNA that is used for targeting. Although highly efficient on-target editing has been reported, off-target events have not been rigorously quantified. In this report we target premature termination codons (PTCs) in messages encoding both a fluorescent reporter protein and the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein transiently transfected into human epithelial cells. We demonstrate that while on-target editing is efficient, off-target editing is extensive, both within the targeted message and across the entire transcriptome of the transfected cells. By redirecting the editing enzymes from the cytoplasm to the nucleus, off-target editing is reduced without compromising the on-target editing efficiency. The addition of the E488Q mutation to the editing enzymes, a common strategy for increasing on-target editing efficiency, causes a tremendous increase in off-target editing. These results underscore the need to reduce promiscuity in current approaches to SDRE.

Introduction to Natural Resources. Second Edition. [Teacher Edition and Student Edition Combined.

ERIC Educational Resources Information Center

Crummett, Dan

These student and teacher guides are designed for a secondary-level course in natural resources that focuses on renewable and nonrenewable natural resources, methods of protecting the environment, and the various careers and technologies available in the natural resources area. The following topics are covered in the course's 10 units: outdoor…

State Teacher Policy Yearbook: What States Can Do to Retain Effective New Teachers, 2008. Alabama

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2008

2008-01-01

This paper presents the Alabama edition of the National Council on Teacher Quality's 2008 "State Teacher Policy Yearbook". The 2008 "Yearbook" focuses on how state policies impact the retention of effective new teachers. This policy evaluation is broken down into three areas that encompass 15 goals. Broadly, these goals examine…

State Teacher Policy Yearbook: What States Can Do to Retain Effective New Teachers, 2008. Idaho

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2008

2008-01-01

This report presents the Idaho edition of the National Council on Teacher Quality's 2008 "State Teacher Policy Yearbook." The 2008 "Yearbook" focuses on how state policies impact the retention of effective new teachers. This policy evaluation is broken down into three areas that encompass 15 goals. Broadly, these goals examine…

Best Practices in Literacy Instruction. Second Edition.

ERIC Educational Resources Information Center

Morrow, Lesley Mandel, Ed.; Gambrell, Linda B., Ed.; Pressley, Michael, Ed.

Now revised and updated, this book's second edition aims to guide teachers in providing effective, engaging literacy instruction that meets the challenges of today's legislative mandates. Identified in the book are principles of best practice that reflect cutting-edge scientific research as well as decades of hands-on classroom experience.…

State Teacher Policy Yearbook: What States Can Do to Retain Effective New Teachers, 2008. South Carolina

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2008

2008-01-01

This paper presents the South Carolina edition of the National Council on Teacher Quality's 2008 "State Teacher Policy Yearbook". The 2008 "Yearbook" focuses on how state policies impact the retention of effective new teachers. This policy evaluation is broken down into three areas that encompass 15 goals. Broadly, these goals…

State Teacher Policy Yearbook: What States Can Do to Retain Effective New Teachers, 2008. New Mexico

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2008

2008-01-01

This paper presents the New Mexico edition of the National Council on Teacher Quality's 2008 "State Teacher Policy Yearbook". The 2008 "Yearbook" focuses on how state policies impact the retention of effective new teachers. This policy evaluation is broken down into three areas that encompass 15 goals. Broadly, these goals…

State Teacher Policy Yearbook: What States Can Do to Retain Effective New Teachers, 2008. New Jersey

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2008

2008-01-01

This paper presents the New Jersey edition of the National Council on Teacher Quality's 2008 "State Teacher Policy Yearbook". The 2008 "Yearbook" focuses on how state policies impact the retention of effective new teachers. This policy evaluation is broken down into three areas that encompass 15 goals. Broadly, these goals…

State Teacher Policy Yearbook: What States Can Do to Retain Effective New Teachers, 2008. New Hampshire

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2008

2008-01-01

This paper presents the New Hampshire edition of the National Council on Teacher Quality's 2008 "State Teacher Policy Yearbook". The 2008 "Yearbook" focuses on how state policies impact the retention of effective new teachers. This policy evaluation is broken down into three areas that encompass 15 goals. Broadly, these goals…

Health Activities Project (HAP), Trial Edition III.

ERIC Educational Resources Information Center

Buller, Dave; And Others

Contained within this Health Activities Project (HAP) trial edition (set III) are a teacher information folio and numerous student activity folios which center around the idea that students in grades 5-8 can control their own health and safety. Each student folio is organized into an Overview, Health Background, Materials, Setting Up, and…

The Law of Teacher Evaluation. Second Edition.

ERIC Educational Resources Information Center

Rossow, Lawrence F.; Tate, James O.

This monograph is a legal treatise covering all legal aspects of the evaluation of teachers. It looks at what can legally be evaluated, how the evaluation can become evidence for termination, and how to avoid and win lawsuits involving wrongful teacher dismissals. It is intended for practicing administrators, supervisors of instruction, teacher…

The High School Mathematics Library. Eighth Edition.

ERIC Educational Resources Information Center

Schaaf, William L.

This eighth edition of the bibliography reflects changes in emphasis in the secondary school mathematics curriculum. The booklet is addressed primarily to high school students of all ability levels and to their mathematics teachers, and should also be of interest to students and instructors of mathematics in two-year colleges as well as librarians…

Health Activities Project (HAP), Trial Edition II.

ERIC Educational Resources Information Center

Buller, Dave; And Others

Contained within this Health Activities Project (HAP) trial edition (set II) are a teacher information folio and numerous student activity folios which center around the idea that students in grades 5-8 can control their own health and safety. Each student folio is organized into a Synopsis, Health Background, Materials, Setting Up, and Activities…

Enriching Student Teaching Relationships. Student Teacher Edition.

ERIC Educational Resources Information Center

Clothier, Grant; Kingsley, Elizabeth

This document seeks to enable student teachers to deal more effectively with their cooperating teachers. The student teaching situation can be a time of stress for the student because of the abrupt change to near-professional status, the experience of being closely supervised by another person in foreign territory, and the knowledge that his…

Introduction to Instrumentation. Teacher Edition.

ERIC Educational Resources Information Center

Brown, A. O., III

This module contains instructional materials on instrumentation to help teachers train students in the job skills they will need as beginning instrumentation technicians. The module addresses the nature of accessing, measuring, and controlling phenomena such as level, flow, pressure, and temperature. Students are introduced to the devices and…

Small Business Management. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This instructor's guide, which is designed to assist teachers in providing instruction and technical support to small business owners and managers, contains 17 competency-based units of instruction on the following areas that both small business instructors and small business owners have deemed critical to the success of any business:…

Literature for Today's Young Adults. Fourth Edition.

ERIC Educational Resources Information Center

Nilsen, Alleen Pace; Donelson, Kenneth L.

Designed to help teachers open young minds to literature, this book presents criteria for evaluating books in all genres and their suggested classroom uses, an examination of hotly debated topics, and an overview of the significance of young adult literature. The fourth edition of the book features 30 boxed inserts containing essays by some of the…

A Model for Flexibly Editing CSCL Scripts

ERIC Educational Resources Information Center

Sobreira, Pericles; Tchounikine, Pierre

2012-01-01

This article presents a model whose primary concern and design rationale is to offer users (teachers) with basic ICT skills an intuitive, easy, and flexible way of editing scripts. The proposal is based on relating an end-user representation as a table and a machine model as a tree. The table-tree model introduces structural expressiveness and…

Material Objects. Basic Edition. Science for Micronesia.

ERIC Educational Resources Information Center

Trust Territory of the Pacific Islands Dept. of Education, Saipan.

Presented is a teacher's guide for an elementary science unit designed for use with first grade students in the Trust Territory of Micronesia. Although there is a degree of similarity to the curriculum materials developed for the Science Curriculum Improvement Study, this Micronesian unit does not purport to be an adaptation or edition of the SCIS…

Counseling Skills for Teachers

ERIC Educational Resources Information Center

Kottler, Jeffrey A.; Kottler, Ellen

2006-01-01

By necessity, today's teachers do much more than deliver instruction. In the classroom, on the playground, or even in the parking lot, teachers are often called upon to respond quickly and appropriately to students' social and emotional needs, drawing from instinct more than anything else. In this second edition of "Counseling Skills for…

Calculus of Elementary Functions, Part I. Teacher's Commentary. Revised Edition.

ERIC Educational Resources Information Center

Herriot, Sarah T.; And Others

This course is intended for students who have a thorough knowledge of college preparatory mathematics including algebra, axiomatic geometry, trigonometry, and analytic geometry. It does not assume they have acquired a background of elementary functions. This teacher's guide contains background information, suggested instructional procedures, and…

Demography and You: Teacher Edition.

ERIC Educational Resources Information Center

McCrea, Lester C.; And Others

This teacher's guide is the grades 7-9 unit for population education developed for the Baltimore public schools. This mini-demography course covers various factors of population growth and change. The activities of the unit focus on seven major concepts: (1) demography provides information for understanding population growth, trends, and changes;…

The Express-Lane Edit: Making Editing Useful for Young Adolescents

ERIC Educational Resources Information Center

Anderson, Jeff

2008-01-01

Editing is a powerful tool for writers, but are our methods of teaching it really demonstrating that power for young adolescents? The author, frustrated with students' inability to edit, blames his own approach and, beginning with a grocery store epiphany, works to develop a more effective system. Elements of his successful approach include time…

Resource Book for Drug Abuse Education. Second Edition.

ERIC Educational Resources Information Center

Nellis, Muriel, Ed.

This second edition of the "Resource Book" assembles a selection of scientific, philosophical, and educational drug abuse literature. The publication, as viewed by its authors, serves as a basis for improved understanding, trust, and communication between teacher and student concerning drug use and its place in both contemporary youth culture and…

Cloud Properties of CERES-MODIS Edition 4 and CERES-VIIRS Edition 1

NASA Technical Reports Server (NTRS)

Sun-Mack, Sunny; Minnis, Patrick; Chang, Fu-Lung; Hong, Gang; Arduini, Robert; Chen, Yan; Trepte, Qing; Yost, Chris; Smith, Rita; Brown, Ricky;

Biotechnology in Agriculture. Teacher Edition.

ERIC Educational Resources Information Center

Peterson, Dennis R.; Rehberger, Thomas

This curriculum guide is designed to help teachers to present a course that emphasizes the interrelationship of science and technology and the impact of this technology on agriculture and agricultural products. The guide contains six units that each contain some or all of the following basic components of a unit of instruction: objective sheet,…

Decay and Renewal. Teacher Edition.

ERIC Educational Resources Information Center

Trautmann, Nancy M.; Krasny, Marianne E.; Carlsen, William S.; Cunningham, Christine M.; Canning, Harry; Carroll, Patricia; Johnson, Mark; Khandar, Alpa; Olynciw, Elaina; Kottler, Bennett; Penningroth, Stephen; Welman, Adam

This teacher guide is part of the Environmental Inquiry (EI) curriculum series developed at Cornell University to enable high school students to conduct authentic environmental science research. The goals of EI are for students to: (1) develop research skills; (2) use their newly acquired skills to conduct research projects of their own design,…

Microwave Oven Repair. Teacher Edition.

ERIC Educational Resources Information Center

Smreker, Eugene

This competency-based curriculum guide for teachers addresses the skills a technician will need to service microwave ovens and to provide customer relations to help retain the customer's confidence in the product and trust in the service company that performs the repair. The guide begins with a task analysis, listing 20 cognitive tasks and 5…

Probing the Natural World, Level III, Record Book, Teacher's Guide: What's Up? Intermediate Science Curriculum Study.

ERIC Educational Resources Information Center

Bonar, John R., Ed.; Hathway, James A., Ed.

This is the teacher's edition of the Record Book for the unit "What's Up" of the Intermediate Science Curriculum Study (ISCS) for level III students (grade 9). The correct answers to the questions from the student text are recorded. An introductory note to the teacher explains how to use the book. Answers are included for the activities…

State Teacher Policy Yearbook, 2009. National Summary

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

The 2009 edition of the "State Teacher Policy Yearbook" is the National Council on Teacher Quality's (NCTQ's) third annual review of state laws, rules and regulations that govern the teaching profession. This year's report is a comprehensive analysis of the full range of each state's teacher policies, measured against a realistic…

State Teacher Policy Yearbook, 2011. National Summary

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2011

2011-01-01

The year 2011 was no ordinary year for teacher policy. In fact, it was a year like no other chronicled by the National Council on Teacher Quality's (NCTQ) "State Teacher Policy Yearbook". This fifth annual edition of the Yearbook documents more changes in state teacher policy than NCTQ has seen in any of its previous top-to-bottom reviews of the…

A Revised Guide for Improving Teacher Education in Human Rights.

ERIC Educational Resources Information Center

Phi Delta Kappa, Bloomington, IN. Commission of Education, Human Rights, and Responsibilities.

This document serves as a guide for teacher education institutions and programs designed to prepare educators for meeting their responsibilities in the area of human rights and human relations. This second edition of the guide represents a substantial modification of the original guide, and includes many activities, experiences, and suggestions…

Calculus of Elementary Functions, Part II. Teacher's Commentary. Revised Edition.

ERIC Educational Resources Information Center

Herriot, Sarah T.; And Others

This course is intended for students who have a thorough knowledge of college preparatory mathematics, including algebra, axiomatic geometry, trigonometry, and analytic geometry. This teacher's guide is for Part II of the course. It is designed to follow Part I of the text. The guide contains background information, suggested instructional…

Our Economy: How It Works. Activities and Investigation. Teacher's Edition.

ERIC Educational Resources Information Center

Clawson, Elmer U.

To help junior and senior high school students develop a better understanding of the United States' economy, this teacher's guide presents a series of learning activities centered around eight general themes. The topics (corresponding to the document's eight chapters) include both international and global economic issues as well as current…

Traffic Flow - USMES Teacher Resource Book. Fourth Edition. Trial Edition.

ERIC Educational Resources Information Center

Keskulla, Jean

This Unified Sciences and Mathematics for Elementary Schools (USMES) unit challenges students to improve traffic flow at a problem location. The challenge is general enough to apply to many problem-solving situations in mathematics, science, social science, and language arts at any elementary school level (grades 1-8). The Teacher Resource Book…

Advanced Respite Care: Medically Challenged. Teacher Edition. Respite Care Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This curriculum guide is designed to help teachers to provide advanced-level training for care providers who want to work with individuals who are chronically or terminally ill and require specialized care. The curriculum contains seven units. Each of the instructional units includes some or all of these basic components: performance objectives,…

Beyond the Wasteland: The Criticism of Broadcasting. Revised Edition.

ERIC Educational Resources Information Center

Smith, Robert Rutherford

This second edition of "Beyond the Wasteland" provides an updated review of broadcast criticism. It offers teachers information to sharpen their own critical capacities and help for exploring media criticism with their students. It also provides suggestions and contextual insights for the mass media researcher. The book is divided into…

Leading the Teacher Induction and Mentoring Program. Second Edition

ERIC Educational Resources Information Center

Sweeny, Barry W.

2007-01-01

While resources are abundant for helping the mentor and the new teacher, very little has been written to guide the leaders of teacher and mentor development. This book provides an effective, proven model for developing, implementing, evaluating, and sustaining an induction and mentoring program that results in highly qualified teachers. A…

How To Help Beginning Teachers Succeed. 2nd Edition.

ERIC Educational Resources Information Center

Gordon, Stephen P.; Maxey, Susan

This book explores the reasons that beginning teachers struggle and provides research-based plans for helping them make the most of their initial teaching years. It proposes Beginning Teacher Assistance Programs (BTAPs) as a practical strategy for success. BTAPs draw on the knowledge and expertise of teachers, principals, central office…

Calculus, Part 3, Teacher's Commentary, Unit No. 71. Revised Edition.

ERIC Educational Resources Information Center

Beck, A.; And Others

This is part three of a three-part manual for teachers using SMSG high school text materials. The overall purpose for each of the chapters is described and the mathematical development detailed. Background information for key concepts and answers for all exercises in each chapter are provided. Chapter topics include: (1) vectors and curves; (2)…

Key Data on Teaching Languages at School in Europe. 2008 Edition

ERIC Educational Resources Information Center

Baidak, Nathalie; Parveva, Teodora

2008-01-01

This second edition of "Key Data on Teaching Languages at School in Europe" contains 44 indicators in five chapters entitled "Context," "Organisation," "Participation," "Teachers" and "Teaching Processes." It has been produced in collaboration with Eurostat and belongs to the "Key…

Adult Learning Methods: A Guide for Effective Instruction. Second Edition.

ERIC Educational Resources Information Center

Galbraith, Michael W., Ed.

This book contains 21 papers devoted to understanding and facilitating adult learning. After "Foreword to the Second Edition" (Malcolm S. Knowles) and other introductory materials, the papers are: "Becoming an Effective Teacher of Adults" (Michael W. Galbraith); "Understanding Adult Learners" (Huey B. Long); "Identifying Your Philosophical…

The levels of edit, second edition

NASA Technical Reports Server (NTRS)

Vanburen, R.; Buehler, M. F.

1980-01-01

The editorial process is analyzed, and five levels of edit are identified. These levels represent cumulative combinations of nine types of edit: Coordination, Policy, Integrity, Screening, Copy Clarification, Format, Mechanical Style, Language, and Substantive. The levels and types of edit, although developed for specific use with external reports at the Jet Propulsion Laboratory, cover the general range of technical editing, especially as it applies to an in-house technical publications organization. Each type of edit is set forth in terms of groups of actions to be performed by editor. The edit-level concept has enhanced understanding and communication among editors, authors, and publications managers concerning the specific editorial work to be done on each manuscript. It has also proved useful as a management tool for estimating and monitoring cost.

Occupational Investigation. Teacher's Handbook. First Edition.

ERIC Educational Resources Information Center

East Texas State Univ., Commerce. Occupational Curriculum Lab.

This teacher's handbook provides suggestions for organization and presentation of resource and instructional materials found in four occupational investigation guides available separately (see Note). Chapter 1 explains Texas Education Agency operations and the Occupational Investigation program and policies. Chapter 2 discusses public relations…

Cellphones in Classrooms Land Teachers on Online Video Sites

ERIC Educational Resources Information Center

Honawar, Vaishali

2007-01-01

Videos of teachers that students taped in secrecy are all over online sites like YouTube and MySpace. Angry teachers, enthusiastic teachers, teachers clowning around, singing, and even dancing are captured, usually with camera phones, for the whole world to see. Some students go so far as to create elaborately edited videos, shot over several…

Good Questions: Great Ways to Differentiate Mathematics Instruction in the Standards-Based Classroom. Third Edition

ERIC Educational Resources Information Center

Small, Marian

2017-01-01

Now in its Third Edition--expanded with over 100 new tasks and questions--this bestselling resource helps experienced and novice teachers to effectively and efficiently differentiate mathematics instruction in grades K-8. Math education expert Marian Small shows teachers how to get started and become expert at using two powerful and universal…

Kids Food CyberClub. Teacher's Guide. First Edition.

ERIC Educational Resources Information Center

Belyea, Monica

This guide is designed to help teachers educate students to be healthier now and in the future. It presents fun, learner-centered activities about nutrition, food, hunger, and food sources. It offers an overview of each section of the Kids Food CyberClub web site, and classroom activities teachers can use to expand on information students will…

Why Teachers Find It Difficult to Include Students with EBD in Mainstream Classes

ERIC Educational Resources Information Center

Gidlund, Ulrika

2018-01-01

In Sweden, teachers in mainstream schools show frustration and insecurity about how to organise education for inclusion and diversity. This article contributes to the understanding of how they articulate their view of the advantages and disadvantages of including students with EBD in mainstream classes. To study teachers' understanding, an…

Diesel Technology: Electrical and Electronic Systems. Teacher Edition [and] Student Edition.

ERIC Educational Resources Information Center

Ready, Allan; Kauffman, Ricky; Bogle, Jerry

This document contains the materials for a competency-based course in diesel technology and electrical and electronic systems that is tied to measurable and observable learning outcomes identified and validated by an advisory committee of business and industry representatives and teachers. The competencies addressed align with the medium/heavy…

Bread in a Bag. Teacher's Packet. Revised Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Education, Oklahoma City.

This unit is designed to familiarize students in grades 3-6 with wheat production; teach them the nutritional value of wheat products and their role in a well-balanced diet; and give then an easy, hands-on experience in bread making with a nominal amount of cleanup for teachers. The kit suggests that in the first week, teachers discuss wheat…

State Teacher Policy Yearbook, 2009. Connecticut

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This Connecticut edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on…

State Teacher Policy Yearbook, 2009. Tennessee

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This Tennessee edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on…

Pipe Drafting with CAD. Teacher Edition.

ERIC Educational Resources Information Center

Smithson, Buddy

This teacher's guide contains nine units of instruction for a course on computer-assisted pipe drafting. The course covers the following topics: introduction to pipe drafting with CAD (computer-assisted design); flow diagrams; pipe and pipe components; valves; piping plans and elevations; isometrics; equipment fabrication drawings; piping design…

Food Service Management. Second Edition. Answer Book/Teacher's Guide. Second Edition.

ERIC Educational Resources Information Center

Hatchett, Melvin S.; Zelade, Richard

This document contains a student assignment book with 22 assignments for a course in food service management and a teacher's guide with answers to the assignments and tips on presenting the lessons to which they pertain. The assignments cover the following topics: career opportunities; entering the food service industry; classifications of…

Educating Children with Multiple Disabilities: A Collaborative Approach. Fourth Edition

ERIC Educational Resources Information Center

Orelove, Fred P., Ed.; Sobsey, Dick, Ed.; Silberman, Rosanne K., Ed.

2004-01-01

Now in its fourth edition, this highly respected, bestselling textbook gives undergraduate and graduate students up-to-the-minute research and strategies for educating children with severe and multiple disabilities. This popular core text--for 15 years, a staple of teacher training programs in special education and related fields--thoroughly…

1001 Best Internet Sites for Educators. 2nd Edition.

ERIC Educational Resources Information Center

Treadwell, Mark

This second edition of a resource designed to help teachers find relevant information on the Internet for both themselves and their students, provides concise reviews of more than 1,000 Web sites sorted by subject area. Each site is evaluated with one to five stars for content, presentation and grade level. Easy-to-follow explanations are provided…

LdShake: Learning Design Solutions Sharing and Co-Edition

ERIC Educational Resources Information Center

Hernandez-Leo, Davinia; Romeo, Lauren; Carralero, Miguel A.; Chacon, Jonathan; Carrio, Mar; Moreno, Pau; Blat, Josep

2011-01-01

Two important challenges that teachers are currently facing are the sharing and the collaborative authoring of their learning design solutions, such as didactical units and learning materials. On the one hand, there are tools that can be used for the creation of design solutions and only some of them facilitate the co-edition. However, they do not…

The Read-Aloud Handbook. Fourth Edition. Revised and Updated.

ERIC Educational Resources Information Center

Trelease, Jim

This new edition of a guide which has made reading aloud a special pleasure for millions of people offers a chance for a new generation of parents, teachers, grandparents, and siblings to discover the rewards--and the necessity--of reading aloud. The guide provides an up-to-date annotated bibliography ("treasury") of more than 1200…

Watershed Dynamics. Teacher Edition (Includes the Full Student Edition). Cornell Scientific Inquiry Series

ERIC Educational Resources Information Center

Carlsen, William S.; Trautmann, Nancy M.

2004-01-01

Whether you're a stream studies novice or a veteran aquatic monitor, "Watershed Dynamics" gives you abundant practical resources to extend your students' investigations into local water quality and land-use issues. This two-part set is ideal for teaching biological and ecological concepts and research techniques. It also shows how the interplay…

State Teacher Policy Yearbook, 2009. Hawaii

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

The Hawaii edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

State Teacher Policy Yearbook, 2009. Idaho

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

The Idaho edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

State Teacher Policy Yearbook, 2009. Utah

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This Utah edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

State Teacher Policy Yearbook, 2009. Maine

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This Maine edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

State Teacher Policy Yearbook, 2009. Alaska

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

The Alaska edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

State Teacher Policy Yearbook, 2009. Kansas

ERIC Educational Resources Information Center

Rosen, Kelli M.; Madden, Trisha M.; Maltz, Stephanie T.; Myers-Preston, Tracey L.

2009-01-01

This Kansas edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

State Teacher Policy Yearbook, 2009. Kentucky

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

The Kentucky edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

State Teacher Policy Yearbook, 2009. Iowa

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

The Iowa edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

Beyond Discipline: From Compliance to Community. 10th Anniversary Edition

ERIC Educational Resources Information Center

Kohn, Alfie

2006-01-01

In this 10th anniversary edition of an Association for Supervision and Curriculum Development (ASCD) best seller, the author reflects on his revolutionary ideas in the context of today's emphasis on school accountability and high-stakes testing. The author relates how his innovative approach--where teachers learn to work with students, rather than…

Collaborative Work and Language Learners' Identities When Editing Academic Texts

ERIC Educational Resources Information Center

Caviedes, Lorena; Meza, Angélica; Rodriguez, Ingrid

2016-01-01

This paper presents a qualitative case study that involved three groups of English as a foreign language pre-service teachers at a Colombian private university. Each group attended tutoring sessions during an academic semester. Along these sessions, students were asked to work collaboratively in the editing process of some chapters of their thesis…

Behavioral Talk-Write as a Method for Teaching Technical Editing.

ERIC Educational Resources Information Center

Gilbertsen, Michael; Killingsworth, M. Jimmie

1987-01-01

Presents a process-oriented method for teachers of stylistic editing workshops that allows them to (1) focus on individual students, (2) start with students basic repertory of responses and build from there, (3) work with freely emitted behavior, (4) ensure frequent and brief responses, and (5) achieve desired behavior through sequential steps.…

High/Scope Buyer's Guide to Children's Software. 11th Edition.

ERIC Educational Resources Information Center

Hohmann, Charles; And Others

This 11th edition of the High/Scope Buyer's Guide to Children's Software was designed to help teachers, caregivers, and parents make good choices when purchasing software to enhance children's learning. The book consists of an introduction, a chapter on finding the best software, software reviews for 48 different software products. The…

Human Germline Genome Editing.

PubMed

Ormond, Kelly E; Mortlock, Douglas P; Scholes, Derek T; Bombard, Yvonne; Brody, Lawrence C; Faucett, W Andrew; Garrison, Nanibaa' A; Hercher, Laura; Isasi, Rosario; Middleton, Anna; Musunuru, Kiran; Shriner, Daniel; Virani, Alice; Young, Caroline E

2017-08-03

With CRISPR/Cas9 and other genome-editing technologies, successful somatic and germline genome editing are becoming feasible. To respond, an American Society of Human Genetics (ASHG) workgroup developed this position statement, which was approved by the ASHG Board in March 2017. The workgroup included representatives from the UK Association of Genetic Nurses and Counsellors, Canadian Association of Genetic Counsellors, International Genetic Epidemiology Society, and US National Society of Genetic Counselors. These groups, as well as the American Society for Reproductive Medicine, Asia Pacific Society of Human Genetics, British Society for Genetic Medicine, Human Genetics Society of Australasia, Professional Society of Genetic Counselors in Asia, and Southern African Society for Human Genetics, endorsed the final statement. The statement includes the following positions. (1) At this time, given the nature and number of unanswered scientific, ethical, and policy questions, it is inappropriate to perform germline gene editing that culminates in human pregnancy. (2) Currently, there is no reason to prohibit in vitro germline genome editing on human embryos and gametes, with appropriate oversight and consent from donors, to facilitate research on the possible future clinical applications of gene editing. There should be no prohibition on making public funds available to support this research. (3) Future clinical application of human germline genome editing should not proceed unless, at a minimum, there is (a) a compelling medical rationale, (b) an evidence base that supports its clinical use, (c) an ethical justification, and (d) a transparent public process to solicit and incorporate stakeholder input. Copyright © 2017 American Society of Human Genetics. All rights reserved.

Making the Journey: Being and Becoming a Teacher of English Language Arts. Second Edition.

ERIC Educational Resources Information Center

Christenbury, Leila

This book takes a look at the realities of classroom life, offering specific suggestions for dealing effectively with today's students. More than a compendium of activities, the first edition of the book introduced educators to a philosophy of teaching illustrated and implemented by workable, realistic techniques. The second edition of the book…

"Teachers and Teaching": From Classroom to Reflection.

ERIC Educational Resources Information Center

Frankes, Lisa

1993-01-01

Book review recommends "Teachers and Teaching," edited by Tom Russell and Hugh Munby, to educators who envision a symbiosis of professional practice and research to promote teacher researchers, suggesting that the book's strength lies in its diversity of forms of enquiry--from narrative dialogs between educators, to case studies, to more…

Advances in targeted genome editing.

PubMed

Perez-Pinera, Pablo; Ousterout, David G; Gersbach, Charles A

2012-08-01

New technologies have recently emerged that enable targeted editing of genomes in diverse systems. This includes precise manipulation of gene sequences in their natural chromosomal context and addition of transgenes to specific genomic loci. This progress has been facilitated by advances in engineering targeted nucleases with programmable, site-specific DNA-binding domains, including zinc finger proteins and transcription activator-like effectors (TALEs). Recent improvements have enhanced nuclease performance, accelerated nuclease assembly, and lowered the cost of genome editing. These advances are driving new approaches to many areas of biotechnology, including biopharmaceutical production, agriculture, creation of transgenic organisms and cell lines, and studies of genome structure, regulation, and function. Genome editing is also being investigated in preclinical and clinical gene therapies for many diseases. Copyright © 2012 Elsevier Ltd. All rights reserved.

Computer Literacy for the Middle Grades. A Teacher's Guide. Revised Edition.

ERIC Educational Resources Information Center

Abington School District, PA.

This guide was planned for a program to acquaint seventh and eighth grade students with the importance of the computer in society and to ensure uniformity of instructional objectives among teachers assigned to teach a beginning-level course in computer literacy. It includes the history of the computer, operating and controlling the computer,…

Teacher's Guide to Architectural Styles. Skinner's Butte Historical District. Revised Edition.

ERIC Educational Resources Information Center

Bauer, Mary; Neimand, Hahn

This document is a teacher's guide to the historic buildings of Eugene, Oregon. Eighteen buildings in the Skinner's Butte Historical District are highlighted, including the U.S. Post Office, the Eagles Building, the Lane Hotel, the Oregon Electric Depot, the Southern Pacific Railroad Depot, and several houses. For each structure there is a brief…

Teaching with Objects and Photographs: A Guide for Teachers. Second Edition

ERIC Educational Resources Information Center

Hatcher, Sarah

2012-01-01

This guide is intended for all teachers who wish to enhance their curriculum by incorporating objects and photographs into their lesson plans. Kindergarten and elementary, middle, and high school classrooms can all benefit from expanded use of these materials. The guide can be used across a range of subject areas including history, community,…

Changing genetic information through RNA editing

NASA Technical Reports Server (NTRS)

Maas, S.; Rich, A.

2000-01-01

RNA editing, the post-transcriptional alteration of a gene-encoded sequence, is a widespread phenomenon in eukaryotes. As a consequence of RNA editing, functionally distinct proteins can be produced from a single gene. The molecular mechanisms involved include single or multiple base insertions or deletions as well as base substitutions. In mammals, one type of substitutional RNA editing, characterized by site-specific base-modification, was shown to modulate important physiological processes. The underlying reaction mechanism of substitutional RNA editing involves hydrolytic deamination of cytosine or adenosine bases to uracil or inosine, respectively. Protein factors have been characterized that are able to induce RNA editing in vitro. A supergene family of RNA-dependent deaminases has emerged with the recent addition of adenosine deaminases specific for tRNA. Here we review the developments that have substantially increased our understanding of base-modification RNA editing over the past few years, with an emphasis on mechanistic differences, evolutionary aspects and the first insights into the regulation of editing activity.

We're Born to Learn: Using the Brain's Natural Learning Process to Create Today's Curriculum. Second Edition

ERIC Educational Resources Information Center

Smilkstein, Rita

2011-01-01

This updated edition of the bestselling book on the brain's natural learning process brings new research results and applications in a power-packed teacher tool kit. Rita Smilkstein shows teachers how to create and deliver curricula that help students become the motivated, successful, and natural learners they were born to be. Updated features…

Strategies That Work: Teaching Comprehension for Understanding and Engagement, Second Edition

ERIC Educational Resources Information Center

Harvey, Stephanie; Goudvis, Anne

2007-01-01

Since its publication in 2000, Strategies That Work has become an indispensable resource for teachers who want to explicitly teach thinking strategies so that students become engaged, thoughtful, independent readers. In this revised and expanded edition, the authors have added twenty completely new comprehension lessons, extending the scope of the…

Discipline with Dignity, 3rd Edition: New Challenges, New Solutions

ERIC Educational Resources Information Center

Curwin, Richard L.; Mendler, Allen N.; Mendler, Brian D.

2008-01-01

Since 1988, this landmark publication has given thousands of teachers timeless advice on not only how to prevent and solve discipline problems but also how to teach discipline as an affirming approach that promotes respect for self and others. Now this expanded 20th Anniversary Edition extends the authors' wisdom to new principles for coping with…

Recombination Narratives to Accompany "A-LM French One," First Edition.

ERIC Educational Resources Information Center

Coughlin, Dorothy

Supplementary recombination narratives intended for use with the 1961 edition of the text "A-LM French One" are designed to help students learn to manipulate basic textual materials. The sample narratives correlate with Units 4-14 of the text. The teacher is urged to make use of the overhead projector when using the narratives for the…

Child Care Teachers' Perspectives on Including Children with Challenging Behavior in Child Care Settings

ERIC Educational Resources Information Center

Quesenberry, Amanda C.; Hemmeter, Mary Louise; Ostrosky, Michaelene M.; Hamann, Kira

2014-01-01

In this study, 9 teachers from 5 child care centers were interviewed to examine their perceptions on including children with challenging behavior in their classrooms. The findings provide a firsthand view into how child care teachers support children's social and emotional development and address challenging behavior. Results confirm previous…

State Teacher Policy Yearbook, 2009. New Mexico

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This New Mexico edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on…

State Teacher Policy Yearbook, 2009. New Hampshire

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This New Hampshire edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on…

State Teacher Policy Yearbook, 2009. South Carolina

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This South Carolina edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on…

State Teacher Policy Yearbook, 2009. New Jersey

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This New Jersey edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on…

State Teacher Policy Yearbook, 2009. North Carolina

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This North Carolina edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on…

State Teacher Policy Yearbook, 2009. New York

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

The New York edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

State Teacher Policy Yearbook, 2009. South Dakota

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This South Dakota edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on…

Government Contract Law (9th Edition)

DTIC Science & Technology

1987-04-01

This Ninth Edition, like its predecessors, will serve as the textbook for the Government Contract Law taught at the School of Systems and Logistics...drawn from Government Contract Law -Cases, 1987 edition, for a rounded approach to the subject. This edition of the text includes coverage of the...Government Contract Law complements the Federal Acquisition Regulation and provides a preventive law treatment for contracting personnel. While it may

Awakening the Sleeping Giant: Helping Teachers Develop as Leaders. Second Edition.

ERIC Educational Resources Information Center

Katzenmayer, Marilyn; Moller, Gayle

This book presents updated research on and examples of teacher leadership, offering practical tips for educators at all levels, tools for self-assessment, and a new vision of the future. The eight chapters are: (1) "What Is Teacher Leadership?" (e.g., definition of teacher leadership, roles for teacher leaders, and who is responsible); (2)…

Rhode Island Model Evaluation & Support System: Teacher. Edition III

ERIC Educational Resources Information Center

Rhode Island Department of Education, 2015

2015-01-01

Rhode Island educators believe that implementing a fair, accurate, and meaningful educator evaluation and support system will help improve teaching and learning. The primary purpose of the Rhode Island Model Teacher Evaluation and Support System (Rhode Island Model) is to help all teachers improve. Through the Model, the goal is to help create a…

Investigation of Techno-Stress Levels of Teachers Who Were Included in Technology Integration Processes

ERIC Educational Resources Information Center

Çoklar, Ahmet Naci; Efilti, Erkan; Sahin, Yusef Levent; Akçay, Arif

2016-01-01

Techno-stress is defined as a modern adaptation disorder resulting from the failure in coping with new technologies in a healthy way. Techno-stress affects many occupational groups, including teachers. FATIH project and many other previous studies conducted in Turkey in recent years have necessitated the use of technology for teachers. The present…

Woman's "True" Profession: Voices from the History of Teaching. 2nd Edition

ERIC Educational Resources Information Center

Hoffman, Nancy

2003-01-01

A rich and fascinating portrait of education life in America between 1830 and 1920, "Woman's 'True' Profession" is an indispensable contribution to our understanding of the teaching profession. "Women have always been teachers." So begins this second edition of Nancy Hoffman's classic history of women and the teaching…

"You're Going to Love This Kid!" Teaching Students with Autism in the Inclusive Classroom, Second Edition

ERIC Educational Resources Information Center

Kluth, Paula

2010-01-01

Thousands of educators have turned to "You're Going to Love this Kid!" for fresh ways to welcome and teach students with autism--and now the book teachers trust is fully revised and more practical than ever! Gathering feedback from teachers across the country during her popular workshops, autism expert Paula Kluth targeted this second edition to…

[Genome editing of industrial microorganism].

PubMed

Zhu, Linjiang; Li, Qi

2015-03-01

Genome editing is defined as highly-effective and precise modification of cellular genome in a large scale. In recent years, such genome-editing methods have been rapidly developed in the field of industrial strain improvement. The quickly-updating methods thoroughly change the old mode of inefficient genetic modification, which is "one modification, one selection marker, and one target site". Highly-effective modification mode in genome editing have been developed including simultaneous modification of multiplex genes, highly-effective insertion, replacement, and deletion of target genes in the genome scale, cut-paste of a large DNA fragment. These new tools for microbial genome editing will certainly be applied widely, and increase the efficiency of industrial strain improvement, and promote the revolution of traditional fermentation industry and rapid development of novel industrial biotechnology like production of biofuel and biomaterial. The technological principle of these genome-editing methods and their applications were summarized in this review, which can benefit engineering and construction of industrial microorganism.

Seven Steps You Can Take to Improve Your Objectives. Third Edition.

ERIC Educational Resources Information Center

Alvir, Claire Gelinas

This document gives examples of seven steps a classroom teacher can take to improve both instructional and learning objectives. This improvement is to be measured by increased student learning. The seven steps are as follows: a) write a simple behavioral objective, b) edit, c) revise objective to make it learner centered, d) clarify, e) evaluate…

State Teacher Policy Yearbook, 2009. District of Columbia

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

The District of Columbia edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive…

Genome Editing in the Cricket, Gryllus bimaculatus.

PubMed

Watanabe, Takahito; Noji, Sumihare; Mito, Taro

2017-01-01

Hemimetabolous, or incompletely metamorphosing, insects are phylogenetically basal and include many beneficial and deleterious species. The cricket, Gryllus bimaculatus, is an emerging model for hemimetabolous insects, based on the success of RNA interference (RNAi)-based gene-functional analyses and transgenic technology. Taking advantage of genome editing technologies in this species would greatly promote functional genomics studies. Genome editing has proven to be an effective method for site-specific genome manipulation in various species. Here, we describe a protocol for genome editing including gene knockout and gene knockin in G. bimaculatus for functional genomics studies.

Mapping Inner Space: Learning and Teaching Visual Mapping. Second Edition.

ERIC Educational Resources Information Center

Margulies, Nancy

More than 10 years ago, when "Mapping Inner Space" was first published, a few teachers were using this creative technique and teaching it to their students. Today mapping is widely used in schools, universities, and the corporate world, as well. This second edition of the book explores a variety of mapping styles and also takes a fresh look at the…

America's Hero to the World, George C. Marshall. Teacher's Guide. Second Edition [and] Resource Packet [and] George C. Marshall: An American Leader. A Teacher's Notebook.

ERIC Educational Resources Information Center

Thompson, Rachel Yarnell; Sittig, Linda H.

This teaching unit about George C. Marshall contains a teacher's guide, a resource packet, and a teacher's notebook. The teacher's guide includes ten introductory, overarching, and culminating activities: (1) About this Guide; (2) Getting to Know Him; (3) Marshal on Video; (4) Share a Space with a Hero; (5) On a Global Stage--Links; (6) A Picture…

The Technique of Film Editing. Enlarged Edition.

ERIC Educational Resources Information Center

Reisz, Karel; Millar, Gavin

Film editing is discussed from the point of view, not only of the person in the cutting room, but also of the person who has responsibility for the final film. Part I outlines the history of editing from the silent film to 1953. It discusses the practice of editing for action, dialogue, comedy, and montage sequences, as well as in documentaries,…

Diesel Technology: Engines. [Teacher and Student Editions.

ERIC Educational Resources Information Center

Barbieri, Dave; Miller, Roger; Kellum, Mary

Competency-based teacher and student materials on diesel engines are provided for a diesel technology curriculum. Seventeen units of instruction cover the following topics: introduction to engine principles and procedures; engine systems and components; fuel systems; engine diagnosis and maintenance. The materials are based on the…

From Teacher to Writer: How Does It Happen?

ERIC Educational Resources Information Center

Lewis, Barbara A.

1992-01-01

Discusses a sixth grade teacher's experience in turning a classroom project into a book. Offers advice for teachers on becoming writers. Explores obstacles, benefits, and suggestions on writing, editing, and publishing work. Describes a class project that resulted in the cleanup of a toxic waste site and the publication of "The Kid's Guide to…

Teachers Learning: Professional Development and Education. Cambridge Education Research Series

ERIC Educational Resources Information Center

McLaughlin, Colleen, Ed.

2012-01-01

"Teachers Learning: Professional Development and Education" is part of The Cambridge Education Research series, edited by senior colleagues at the University of Cambridge Faculty of Education, which has a longstanding tradition of involvement in high quality, innovative teacher education and continuing professional development.…

Genome-wide identification of RNA editing in hepatocellular carcinoma.

PubMed

Kang, Lin; Liu, Xiaoqiao; Gong, Zhoulin; Zheng, Hancheng; Wang, Jun; Li, Yingrui; Yang, Huanming; Hardwick, James; Dai, Hongyue; Poon, Ronnie T P; Lee, Nikki P; Mao, Mao; Peng, Zhiyu; Chen, Ronghua

2015-02-01

We did whole-transcriptome sequencing and whole-genome sequencing on nine pairs of Hepatocellular carcinoma (HCC) tumors and matched adjacent tissues to identify RNA editing events. We identified mean 26,982 editing sites with mean 89.5% canonical A→G edits in each sample using an improved bioinformatics pipeline. The editing rate was significantly higher in tumors than adjacent normal tissues. Comparing the difference between tumor and normal tissues of each patient, we found 7 non-synonymous tissue specific editing events including 4 tumor-specific edits and 3 normal-specific edits in the coding region, as well as 292 edits varying in editing degree. The significant expression changes of 150 genes associated with RNA editing were found in tumors, with 3 of the 4 most significant genes being cancer related. Our results show that editing might be related to higher gene expression. These findings indicate that RNA editing modification may play an important role in the development of HCC. Copyright © 2014 Elsevier Inc. All rights reserved.

Contemporary Literacies and Technologies in English Language Arts Teacher Education: Shift Happens!

ERIC Educational Resources Information Center

George, Marshall; Pope, Carol; Reid, Louann

2015-01-01

Three leaders of the National Council of Teachers of English (NCTE) Conference on English Education (CEE) reflect on the changes that have occurred in English language arts teacher education in the past 15 years since the first edition of "Contemporary Issues in Technology and Teacher Education" ("CITE Journal") was published.…

Millennial Teachers of Color

ERIC Educational Resources Information Center

Dilworth, Mary E., Ed.

2018-01-01

"Millennial Teachers of Color" explores the opportunities and challenges for creating and sustaining a healthy teaching force in the United States. Millennials are the largest generational cohort in American history, with approximately ninety million members and, of these, roughly 43 percent are people of color. This book, edited by…

What do mathematics teachers and teacher trainees know about the history of mathematics?

NASA Astrophysics Data System (ADS)

Gazit, Avikam

2013-06-01

The aim of this study is to present the findings of a study that examined the knowledge of mathematics teachers and teacher trainees, in different tracks, about the concepts, topics and characters from the history of mathematics. The findings indicate a lack of knowledge concerning most of the topics examined. Only about 40% of the participants knew about the origin of our counting system and the only item that reached above 50% was the item relating to the man who edited the book which is the basis for the plane geometry - Euclid (about 83%). Another meaningful finding was that the group with the highest score was that of mathematics teacher trainees in the accelerated track - a unique training scheme for middle school teachers (65.7%). The group with the lowest score was that of the elementary school mathematics student teachers (19.3%). One obvious conclusion is that we need to strengthen the knowledge of the history of mathematics in teacher training and in-service teachers' advanced studies.

Teaching with Emotional Intelligence: A Step-By-Step Guide for Higher and Further Education Professionals. 2nd Edition

ERIC Educational Resources Information Center

Mortiboys, Alan

2011-01-01

The way teachers shape and handle their own feelings and those of their learners is central to the success of learning. Now in its second edition, "Teaching with Emotional Intelligence" shows how to manage this influential yet neglected area of learning and teaching. This practical book looks at how lecturers and teachers can develop and use their…

Trying to Contain Ourselves: A Dialogic Review of the "MLA Handbook, Eighth Edition"

ERIC Educational Resources Information Center

Walker, Janice R.; Kelly, Erin E.

2017-01-01

Since the 2016 release of the Modern Language Association's new style guidelines, scholars and teachers--along with writing centers, libraries, and editorial staffs--have been familiarizing themselves with the changes. Based on a standardized approach to citation, the eighth edition of the "MLA Handbook" asks us to adjust some…

Kaleidoscope: A Multicultural Booklist for Grades K-8. Fourth Edition. NCTE Bibliography Series.

ERIC Educational Resources Information Center

Hansen-Krening, Nancy, Ed.; Aoki, Elaine M., Ed.; Mizokawa, Donald T., Ed.

The fourth edition of this annotated bibliography collection offers students, teachers, and librarians a helpful guide to the best multicultural literature (published from 1999 to 2001) for elementary and middle school readers. The book continues a tradition of promoting unity through diversity by highlighting fiction and nonfiction published by…

Exploring Technology Education. Second Edition. Teacher Guide.

ERIC Educational Resources Information Center

Murray, Steve

This color-coded guide was developed to help teachers provide middle school and junior high students with an activity-oriented approach to learning and thinking about technology. Through the instruction and the activities, students are shown how the different systems interrelate, how they influence everyday life, and how they combine in a…

Engaging Children's Minds: The Project Approach. Second Edition.

ERIC Educational Resources Information Center

Katz, Lilian G.; Chard, Sylvia C.

Noting that much has happened in the field of early childhood education during the 10 years since publication of the first edition of "The Project Approach," this new edition re-introduces the project approach and suggests applications and examples of the approach in action. Notable additions to this second edition include: (1) two new…

10 Myths & Realities about Community College Teacher Education Programs. Second Edition

ERIC Educational Resources Information Center

Maricopa Community Colleges, 2009

2009-01-01

As community colleges emerge as a solution to the teacher quality and shortage issue, the National Association of Community College Teacher Education Programs (NACCTEP) created this pamphlet in an attempt to dispel any misperceptions individuals may have about the community college role in teacher education. "10 Myths About Community College…

The Lecturer's Toolkit: A Resource for Developing Learning, Teaching & Assessment. Second Edition.

ERIC Educational Resources Information Center

Race, Phil

This "toolkit" ring binder is designed to help teachers develop their professional practice in higher education and to enhance their instruction and assessment. A smaller bound version of this second edition is designed to be used by individual lecturers as their personal copy; it contains fewer tasks and activities. The chapters are: (1)…

Basic Automotive Responsibilities. Life Skills. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This teacher's guide is designed for use in presenting a four-unit course in basic automotive responsibilities that is part of a life skills series intended to help students become more self-sufficient in their personal and professional lives. The course's four instructional units cover these topics: purchasing a motor vehicle, maintaining a motor…

Winds and Weather, Teacher's Edition. Probing the Natural World/3.

ERIC Educational Resources Information Center

Florida State Univ., Tallahassee. Dept. of Science Education.

The teacher's edtion for the Intermediate Science Curriculum Study Level III unit entitled "Winds and Weather" provides instructions for teachers for examining some principles underlying thermal convention, weather observation, closed systems, moisture and cloud formation, the heated-air model, and fronts. A brief introduction dealing…

Trypanosoma brucei RNA Editing Complex

PubMed Central

O'Hearn, Sean F.; Huang, Catherine E.; Hemann, Mike; Zhelonkina, Alevtina; Sollner-Webb, Barbara

2003-01-01

Maturation of Trypanosoma brucei mitochondrial mRNA involves massive posttranscriptional insertion and deletion of uridine residues. This RNA editing utilizes an enzymatic complex with seven major proteins, band I through band VII. We here use RNA interference (RNAi) to examine the band II and band V proteins. Band II is found essential for viability; it is needed to maintain the normal structure of the editing complex and to retain the band V ligase protein. Previously, band III was found essential for certain activities, including maintenance of the editing complex and retention of the band IV ligase protein. Thus, band II and band V form a protein pair with features analogous to the band III/band IV ligase pair. Since band V is specific for U insertion and since band IV is needed for U deletion, their parallel organization suggests that the editing complex has a pseudosymmetry. However, unlike the essential band IV ligase, RNAi to band V has only a morphological but no growth rate effect, suggesting that it is stimulatory but nonessential. Indeed, in vitro analysis of band V RNAi cell extract demonstrates that band IV can seal U insertion when band V is lacking. Thus, band IV ligase is the first activity of the basic editing complex shown able to serve in both forms of editing. Our studies also indicate that the U insertional portion may be less central in the editing complex than the corresponding U deletional portion. PMID:14560033

Probability & Statistics: Modular Learning Exercises. Teacher Edition

ERIC Educational Resources Information Center

Actuarial Foundation, 2012

2012-01-01

The purpose of these modules is to provide an introduction to the world of probability and statistics to accelerated mathematics students at the high school level. The modules also introduce students to real world math concepts and problems that property and casualty actuaries come across in their work. They are designed to be used by teachers and…

Power Product Equipment Technician: Outboard-Engine Boat Systems. Teacher Edition [and] Student Edition.

ERIC Educational Resources Information Center

Hilley, Robert

This curriculum guide contains teacher and student materials for a course on outboard-engine boat systems for power product equipment technician occupations. The course contains the following three units of instruction: (1) Orientation to Outboard-Engine Boat Systems and Rigging; (2) Trailers and Safe Towing and Boat Operation; and (3) Seasonal…

Teacher Learning that Matters: International Perspectives. Routledge Research in Education

ERIC Educational Resources Information Center

Kooy, Mary, Ed.; van Veen, Klaas, Ed.

2011-01-01

In the continuing global call for educational reforms and change, the contributors in this edited collection address the critical issue of teacher learning from diverse national contexts and perspectives. They define "teacher learning that matters" as it shapes and directs pedagogical practices with the goal of improving student learning. Student…

Reading Assessment: Principles and Practices for Elementary Teachers. Second Edition

ERIC Educational Resources Information Center

Barrentine, Shelby J., Ed.; Stokes, Sandra M., Ed.

2005-01-01

How do teachers respond to the competing pressures of school accountability, high-stakes testing, classroom assessment and instruction? This updated collection of articles from The Reading Teacher can help. Readers will find tools for: (1) Building school assessment policies; (2) Helping students succeed on high-stakes tests; (3) Using assessment…

Mainstream Teachers about Including Deaf or Hard of Hearing Students

ERIC Educational Resources Information Center

Vermeulen, Jorine A.; Denessen, Eddie; Knoors, Harry

2012-01-01

This study is aimed at teachers' classroom practices and their beliefs and emotions regarding the inclusion of deaf or hard of hearing (d/hh) students in mainstream secondary schools. Nine teachers in two schools were interviewed about the inclusion of d/hh students. These teachers were found to consider the d/hh students' needs in their teaching…

Quantifying on- and off-target genome editing.

PubMed

Hendel, Ayal; Fine, Eli J; Bao, Gang; Porteus, Matthew H

2015-02-01

Genome editing with engineered nucleases is a rapidly growing field thanks to transformative technologies that allow researchers to precisely alter genomes for numerous applications including basic research, biotechnology, and human gene therapy. While the ability to make precise and controlled changes at specified sites throughout the genome has grown tremendously in recent years, we still lack a comprehensive and standardized battery of assays for measuring the different genome editing outcomes created at endogenous genomic loci. Here we review the existing assays for quantifying on- and off-target genome editing and describe their utility in advancing the technology. We also highlight unmet assay needs for quantifying on- and off-target genome editing outcomes and discuss their importance for the genome editing field. Copyright © 2014 Elsevier Ltd. All rights reserved.

MENTAL DEFICIENCY. SECOND EDITION.

ERIC Educational Resources Information Center

HILLIARD, L.T.; KIRMAN, BRIAN H.

REVISED TO INCLUDE LEGISLATIVE AND ADMINISTRATIVE PROCEDURES NEW IN BRITAIN SINCE THE 1957 EDITION, THE TEXT INCLUDES RECENT ADVANCES IN ETIOLOGY, PATHOLOGY, AND TREATMENT OF MENTAL DEFICIENCY. CONSIDERATION OF THE BACKGROUND OF MENTAL DEFICIENCY INCLUDES HISTORICAL AND LEGAL ASPECTS, THE SOCIAL BACKGROUND OF MENTAL DEFECT, PRENATAL CAUSES OF…

Wikipedia editing dynamics.

PubMed

Gandica, Y; Carvalho, J; Sampaio Dos Aidos, F

2015-01-01

A model for the probabilistic function followed in editing Wikipedia is presented and compared with simulations and real data. It is argued that the probability of editing is proportional to the editor's number of previous edits (preferential attachment), to the editor's fitness, and to an aging factor. Using these simple ingredients, it is possible to reproduce the results obtained for Wikipedia editing dynamics for a collection of single pages as well as the averaged results. Using a stochastic process framework, a recursive equation was obtained for the average of the number of edits per editor that seems to describe the editing behavior in Wikipedia.

Wikipedia editing dynamics

NASA Astrophysics Data System (ADS)

Gandica, Y.; Carvalho, J.; Sampaio dos Aidos, F.

2015-01-01

A model for the probabilistic function followed in editing Wikipedia is presented and compared with simulations and real data. It is argued that the probability of editing is proportional to the editor's number of previous edits (preferential attachment), to the editor's fitness, and to an aging factor. Using these simple ingredients, it is possible to reproduce the results obtained for Wikipedia editing dynamics for a collection of single pages as well as the averaged results. Using a stochastic process framework, a recursive equation was obtained for the average of the number of edits per editor that seems to describe the editing behavior in Wikipedia.

The First-Year Teacher: Teaching with Confidence (K-8). New Revised Edition.

ERIC Educational Resources Information Center

Bosch, Karen A.; Kersey, Katharine C.

This book offers beginning teachers daily step-by-step plans for the first 4 weeks of school. It is based on a survey of first year teachers that examined their problems, concerns, needs, and feelings. It is also based on a task force of preservice and inservice teachers who set an agenda and tasks to find out more about beginning teacher needs.…

Dialogue for Change. Options for Re-Structuring K-12 Education. 3rd Edition, 1988.

ERIC Educational Resources Information Center

Metropolitan Affairs Corp., Detroit, MI.

This Third Edition of the 1985 report, "Dialogue for Change," discusses options and examples of educational choice and teacher empowerment and summarizes developments between 1985 and 1987. The following key options are discussed in Chapter 1, "Proposed Options for Change": (1) magnet schools; (2) open enrollment; (3) purchase…

A Celebration of Teachers for the Diamond Jubilee of the National Council of Teachers of English. New Edition.

ERIC Educational Resources Information Center

National Council of Teachers of English, Urbana, IL.

Recognition of teachers has been a focus of the Diamond Jubilee Year of the National Council of Teachers of English (1985-86), which honors the outstanding teachers of some of the nation's leaders in this collection of testimonials about the influence these teachers have had on their lives. Contributors to the collection are Margaret Walker…

Genome Editing of Monogenic Neuromuscular Diseases

PubMed Central

Long, Chengzu; Amoasii, Leonela; Bassel-Duby, Rhonda; Olson, Eric N.

2017-01-01

IMPORTANCE Muscle weakness, the most common symptom of neuromuscular disease, may result from muscle dysfunction or may be caused indirectly by neuronal and neuromuscular junction abnormalities. To date, more than 780 monogenic neuromuscular diseases, linked to 417 different genes, have been identified in humans. Genome-editing methods, especially the CRISPR (clustered regularly interspaced short palindromic repeats)–Cas9 (CRISPR-associated protein 9) system, hold clinical potential for curing many monogenic disorders, including neuromuscular diseases such as Duchenne muscular dystrophy, spinal muscular atrophy, amyotrophic lateral sclerosis, and myotonic dystrophy type 1. OBJECTIVES To provide an overview of genome-editing approaches; to summarize published reports on the feasibility, efficacy, and safety of current genome-editing methods as they relate to the potential correction of monogenic neuromuscular diseases; and to highlight scientific and clinical opportunities and obstacles toward permanent correction of disease-causing mutations responsible for monogenic neuromuscular diseases by genome editing. EVIDENCE REVIEW PubMed and Google Scholar were searched for articles published from June 30, 1989, through June 9, 2016, using the following keywords: genome editing, CRISPR-Cas9, neuromuscular disease, Duchenne muscular dystrophy, spinal muscular atrophy, amyotrophic lateral sclerosis, andmyotonic dystrophy type 1. The following sources were reviewed: 341 articles describing different approaches to edit mammalian genomes; 330 articles describing CRISPR-Cas9–mediated genome editing in cell culture lines (in vitro) and animal models (in vivo); 16 websites used to generate single-guide RNA; 4 websites for off-target effects; and 382 articles describing viral and nonviral delivery systems. Articles describing neuromuscular diseases, including Duchenne muscular dystrophy, spinal muscular atrophy, amyotrophic lateral sclerosis, and myotonic dystrophy type 1

The technical editing internship: What makes it work

DOE Office of Scientific and Technical Information (OSTI.GOV)

Caruthers, C.M.; Caruthers, L.E.; Schmidt, B.J.

1988-01-01

The following paper presents the experiences and perceptions of the three main participants of a technical editing internship at Argonne National Laboratory during the summer of 1986. Linda Caruthers, Clifford Caruthers, and Bryan Schmidt/emdash/teacher, supervisor, and intern, respectively/emdash/share what they received as their roles and responsibilities in guiding, managing, and becoming an entry-level technical editor. The following discussions demonstrate how the efforts of three people pursuing different objectives achieve the primary goal of all technical writers and editors: high-quality publications.

Critical Pedagogy for Rural Teachers?

ERIC Educational Resources Information Center

Theobald, Paul; Theobald, Jan

Three books represent the recent work of leading U.S. proponents of critical approaches to pedagogy: "Life in Schools: An Introduction to Critical Pedagogy in the Foundations of Education," by Peter McLaren; "Freire for the Classroom: A Sourcebook for Liberatory Teaching," edited by Ira Shor; and "Teachers as…

RNA Editing and Its Molecular Mechanism in Plant Organelles

PubMed Central

Ichinose, Mizuho; Sugita, Mamoru

2016-01-01

RNA editing by cytidine (C) to uridine (U) conversions is widespread in plant mitochondria and chloroplasts. In some plant taxa, “reverse” U-to-C editing also occurs. However, to date, no instance of RNA editing has yet been reported in green algae and the complex thalloid liverworts. RNA editing may have evolved in early land plants 450 million years ago. However, in some plant species, including the liverwort, Marchantia polymorpha, editing may have been lost during evolution. Most RNA editing events can restore the evolutionarily conserved amino acid residues in mRNAs or create translation start and stop codons. Therefore, RNA editing is an essential process to maintain genetic information at the RNA level. Individual RNA editing sites are recognized by plant-specific pentatricopeptide repeat (PPR) proteins that are encoded in the nuclear genome. These PPR proteins are characterized by repeat elements that bind specifically to RNA sequences upstream of target editing sites. In flowering plants, non-PPR proteins also participate in multiple RNA editing events as auxiliary factors. C-to-U editing can be explained by cytidine deamination. The proteins discovered to date are important factors for RNA editing but a bona fide RNA editing enzyme has yet to be identified. PMID:28025543

Genome-editing Technologies for Gene and Cell Therapy.

PubMed

Maeder, Morgan L; Gersbach, Charles A

2016-03-01

Gene therapy has historically been defined as the addition of new genes to human cells. However, the recent advent of genome-editing technologies has enabled a new paradigm in which the sequence of the human genome can be precisely manipulated to achieve a therapeutic effect. This includes the correction of mutations that cause disease, the addition of therapeutic genes to specific sites in the genome, and the removal of deleterious genes or genome sequences. This review presents the mechanisms of different genome-editing strategies and describes each of the common nuclease-based platforms, including zinc finger nucleases, transcription activator-like effector nucleases (TALENs), meganucleases, and the CRISPR/Cas9 system. We then summarize the progress made in applying genome editing to various areas of gene and cell therapy, including antiviral strategies, immunotherapies, and the treatment of monogenic hereditary disorders. The current challenges and future prospects for genome editing as a transformative technology for gene and cell therapy are also discussed.

Genome-editing Technologies for Gene and Cell Therapy

PubMed Central

Maeder, Morgan L; Gersbach, Charles A

2016-01-01

Gene therapy has historically been defined as the addition of new genes to human cells. However, the recent advent of genome-editing technologies has enabled a new paradigm in which the sequence of the human genome can be precisely manipulated to achieve a therapeutic effect. This includes the correction of mutations that cause disease, the addition of therapeutic genes to specific sites in the genome, and the removal of deleterious genes or genome sequences. This review presents the mechanisms of different genome-editing strategies and describes each of the common nuclease-based platforms, including zinc finger nucleases, transcription activator-like effector nucleases (TALENs), meganucleases, and the CRISPR/Cas9 system. We then summarize the progress made in applying genome editing to various areas of gene and cell therapy, including antiviral strategies, immunotherapies, and the treatment of monogenic hereditary disorders. The current challenges and future prospects for genome editing as a transformative technology for gene and cell therapy are also discussed. PMID:26755333

Generation of gene edited birds in one generation using sperm transfection assisted gene editing (STAGE).

PubMed

Cooper, Caitlin A; Challagulla, Arjun; Jenkins, Kristie A; Wise, Terry G; O'Neil, Terri E; Morris, Kirsten R; Tizard, Mark L; Doran, Timothy J

2017-06-01

Generating transgenic and gene edited mammals involves in vitro manipulation of oocytes or single cell embryos. Due to the comparative inaccessibility of avian oocytes and single cell embryos, novel protocols have been developed to produce transgenic and gene edited birds. While these protocols are relatively efficient, they involve two generation intervals before reaching complete somatic and germline expressing transgenic or gene edited birds. Most of this work has been done with chickens, and many protocols require in vitro culturing of primordial germ cells (PGCs). However, for many other bird species no methodology for long term culture of PGCs exists. Developing methodologies to produce germline transgenic or gene edited birds in the first generation would save significant amounts of time and resource. Furthermore, developing protocols that can be readily adapted to a wide variety of avian species would open up new research opportunities. Here we report a method using sperm as a delivery mechanism for gene editing vectors which we call sperm transfection assisted gene editing (STAGE). We have successfully used this method to generate GFP knockout embryos and chickens, as well as generate embryos with mutations in the doublesex and mab-3 related transcription factor 1 (DMRT1) gene using the CRISPR/Cas9 system. The efficiency of the method varies from as low as 0% to as high as 26% with multiple factors such as CRISPR guide efficiency and mRNA stability likely impacting the outcome. This straightforward methodology could simplify gene editing in many bird species including those for which no methodology currently exists.

Ideas Para Fortalecer Las Destrezas en Matematicas. Ideas for Strengthening Mathematics Skills. Spanish Edition.

ERIC Educational Resources Information Center

New York State Education Dept., Albany. Bureau of Bilingual Education.

Presented is an overview of some specific schemes that have been used successfully by teachers throughout New York State to strengthen basic mathematics skills. Components offer ideas that have been successful with primary, intermediate, and secondary students. The contents of this Spanish language edition are identical to the English language and…

Idee Per Consolidare Le Abilita In Matematica. Ideas for Strengthening Mathematics Skills. Italian Edition.

ERIC Educational Resources Information Center

New York State Education Dept., Albany. Bureau of Bilingual Education.

Presented is an overview of some specific schemes that have been used successfully by teachers throughout New York State to strengthen basic mathematics skills. Components offer ideas that have been successful with primary, intermediate, and secondary students. The contents of this Italian language edition are identical to the English language and…

The Mathematics Education of Elementary Teachers: Issues and Strategies for Content Courses

ERIC Educational Resources Information Center

Hart, Lynn C., Ed.; Oesterle, Susan, Ed.; Auslander, Susan Swars, Ed.; Kajander, Ann, Ed.

2016-01-01

This book is an edited volume addressing specific issues of significance for individuals involved with the undergraduate mathematics content preparation of prospective elementary teachers (PSTs). Teaching mathematics content courses to this group of students presents unique challenges. While some PSTs enter their teacher preparation with weak…

Teachers' learning about research for enhancing students' thinking skills in science learning

NASA Astrophysics Data System (ADS)

Nammungkhun, Wisanugorn; Satchukorn, Sureerat; Saenpuk, Nudchanard; Yuenyong, Chokchai; Chantharanuwong, Warawun

2018-01-01

This paper aimed to clarify teachers' learning about research for enhancing students' thinking skills in science learning. The study applied the lens of sociocultural view of learning to discuss teachers' learning about research. Participants included teachers who participated in the project of thinking research schools: research for enhancing students' thinking skills. The project of thinking research schools provided participants chance to learn knowledge about research and thinking research, doing research and publication, and participate in the international conference. Methodology regarded ethnographic research. The tools of interpretation included participant observation, interview, and document analysis. The researchers as participants of the research project of thinking research schools tried to clarify what they learned about research from their way of seeing the view of research about enhancing students' thinking skills through participant observation. The findings revealed what and how teachers as apprenticeship learn about research through legitimate peripheral participation in the research project community of practice. The paper clarified teachers' conceptualization about research for enhancing students' thinking through the workshop, doing research, writing up research article with supported by experts, presenting research in the international conference, editing their research article on the way of publishing, and so on.

Inquiring minds: Case studies of two middle school science teachers as they include inquiry and graphing in their curricula

NASA Astrophysics Data System (ADS)

Scarano, Grace Hotchkiss

2000-10-01

Current reform documents in science and mathematics call for teachers to include inquiry and data analysis in their teaching. This interpretive quasi-ethnographic case study examined two middle school science teachers as they planned and implemented inquiry and graphing in their science curricula. The focus question for this research was: What are middle school science teachers' experiences as they include graphing and inquiry-based student research projects in their curricula? How is teaching these areas different from usual teaching? The research examined two teachers teaching their favorite unit, parts of other familiar units, graphing, and student inquiry. Four main types of data were gathered: (1) observations of teachers' instruction, (2) interviews and meetings with the teachers, (3) curricular artifacts, and (4) questionnaires and other written material. The study took place over a seven-month period. The findings revealed that these two teachers had different ideologies of schooling and that these ideologies shaped the teachers' planning and implementation of their usual content as well as graphing and inquiry. One teacher's ideology was technical, and the other's was constructive. Six themes emerged as salient features of their teaching: (1) the role of developing a vision for curricular implementation, (2) curricular decisions: internal and external authority, (3) views of knowing and learning, (4) perceptions of the nature of science, (5) attending to a personal concern in teaching, and (6) reflection. The textures of these themes varied between the two teachers, and formed a coherent yet dynamic system within which each teacher maneuvered. This study found that both teachers found it challenging to include inquiry in their curricula, even though both had attended workshops designed to help teachers use student inquiry. The constructive teacher's implementation was more in line with the notions that are central to constructivism and current non

Annual Editions: Early Childhood Education 06/07

ERIC Educational Resources Information Center

Paciorek, Karen Menke, Ed.

2006-01-01

This 27th edition of "Annual Editions: Early Childhood Education" provides convenient, inexpensive access to current articles selected from the best of the public press. Organizational features include: an annotated listing of selected World Wide Web sites; an annotated table of contents; a topic guide; a general introduction; brief overviews for…

The Minority Experience: A Basic Bibliography of American Ethnic Studies. Revised and Enlarged Edition.

ERIC Educational Resources Information Center

Caselli, Ron, Comp.

Approximately 1500 books published between 1940 and 1974 constitute this revised edition of the 1970 minority experience bibliography. It is said to be directed at teachers in inservice activities and students of American minority groups. Afro-Americans and native Americans are covered with additional sections on the Asian-American, Euro-American,…

Teaching Science in Elementary and Middle School: A Cognitive and Cultural Approach. Second Edition

ERIC Educational Resources Information Center

Buxton, Cory A.; Provenzo, Eugene F., Jr.

2010-01-01

Featuring an increased emphasis on the way today's changing science and technology is shaping our culture, this Second Edition of "Teaching Science in Elementary and Middle School" provides pre- and in-service teachers with an introduction to basic science concepts and methods of science instruction, as well as practical strategies for the…

Digital In, Digital Out: Digital Editing with Firewire.

ERIC Educational Resources Information Center

Doyle, Bob; Sauer, Jeff

1997-01-01

Reviews linear and nonlinear digital video (DV) editing equipment and software, using the IEEE 1394 (FireWire) connector. Includes a chart listing specifications and rating eight DV editing systems, reviews two DV still-photo cameras, and previews beta DV products. (PEN)

Pedagogical and Social Climate in School Questionnaire: Factorial Validity and Reliability of the Teacher Version

ERIC Educational Resources Information Center

Dimitrova, Radosveta; Ferrer-Wreder, Laura; Galanti, Maria Rosaria

2016-01-01

This study evaluated the factorial structure of the Pedagogical and Social Climate in School (PESOC) questionnaire among 307 teachers in Bulgaria. The teacher edition of PESOC consists of 11 scales (i.e., Expectations for Students, Unity Among Teachers, Approach to Students, Basic Assumptions About Students' Ability to Learn, School-Home…

Teachers as Writers: Who Me?

ERIC Educational Resources Information Center

Way, Jenni

2004-01-01

In an earlier edition of this journal, Paul Swan (1997) published an article called "Writing for journals: An avenue for professional development". His article encourages teachers to share their experiences and ideas by becoming writers of APMC journal articles, and in doing so, engage in professional development. The set of guidelines Swan…

African Studies Curriculum Materials for Teachers. Second Edition.

ERIC Educational Resources Information Center

Illinois Univ., Urbana. Center for African Studies.

This handbook features an exhaustive collection of African studies curriculum materials considered most appropriate for teachers. The material is coded for elementary school, middle school, senior high school/adult, and general interest. Material is presented in the following chapters: "General Information" which contains facts sheets on…

Primordial germ cell-mediated transgenesis and genome editing in birds.

PubMed

Han, Jae Yong; Park, Young Hyun

2018-01-01

Transgenesis and genome editing in birds are based on a unique germline transmission system using primordial germ cells (PGCs), which is quite different from the mammalian transgenic and genome editing system. PGCs are progenitor cells of gametes that can deliver genetic information to the next generation. Since avian PGCs were first discovered in nineteenth century, there have been numerous efforts to reveal their origin, specification, and unique migration pattern, and to improve germline transmission efficiency. Recent advances in the isolation and in vitro culture of avian PGCs with genetic manipulation and genome editing tools enable the development of valuable avian models that were unavailable before. However, many challenges remain in the production of transgenic and genome-edited birds, including the precise control of germline transmission, introduction of exogenous genes, and genome editing in PGCs. Therefore, establishing reliable germline-competent PGCs and applying precise genome editing systems are critical current issues in the production of avian models. Here, we introduce a historical overview of avian PGCs and their application, including improved techniques and methodologies in the production of transgenic and genome-edited birds, and we discuss the future potential applications of transgenic and genome-edited birds to provide opportunities and benefits for humans.

Introduction to Natural Resources. Third Edition. Teacher Edition [and] Student Guide [and] Student Workbook.

ERIC Educational Resources Information Center

Hehn, Darold; Newport, Bob

These student and teacher guides are designed for a secondary-level course in natural resources that focuses on renewable and nonrenewable natural resources, methods of protecting the environment, and the various careers and technologies available in the natural resources area. The following topics are covered in the course's 10 units: outdoor…

Power Product Equipment Technician: Outboard-Engine Systems and Service. Teacher Edition [and] Student Edition.

ERIC Educational Resources Information Center

Hilley, Robert

This curriculum guide contains teacher and student materials for a course on outboard-engine boat systems and service for power product equipment technician occupations. The course contains the following four units of instruction: (1) Outboard-Engine Design and Identification; (2) Operation and Service of Engine-Support Systems; (3) Operation and…

Government: The Decision-Making Process. A Resource Manual for Teachers and Students. Revised Edition.

ERIC Educational Resources Information Center

Khanlian, John F.; Wallin, Katherine L.

This guide for high school political science teachers focuses on political decision making. The program emphasizes experiential learning through utilizing community and state resources and implementing field study and internships for students. The document is presented in eight sections. The introduction includes a values survey and suggestions…

Laboratory Experiences in Marine Biology for Upper Elementary and Secondary School Grades, Teachers Edition.

ERIC Educational Resources Information Center

Raimist, Roger J.

Designed to assist the teacher who wishes to use marine organisms for biological laboratory investigations, this manual includes general information on maintaining marine aquaria and collecting marine organisms as well as five tested laboratory exercises. The exercises deal with the measurement of oxygen consumption (giving techniques for…

Criminal Justice in America. Teacher's Guide. Second Edition.

ERIC Educational Resources Information Center

Croddy, Marshall; Hayes, Bill

This teacher's guide outlines effective strategies for using "Criminal Justice in America." This comprehensive textbook on criminal justice may serve either as the foundation for a high school law-related education course or as a supplemental text for civics, government or contemporary-issues courses. Designed to foster critical thinking…

[Genome-editing: focus on the off-target effects].

PubMed

He, Xiubin; Gu, Feng

2017-10-25

Breakthroughs of genome-editing in recent years have paved the way to develop new therapeutic strategies. These genome-editing tools mainly include Zinc-finger nucleases (ZFNs), Transcription activator-like effector nucleases (TALENs), and clustered regulatory interspaced short palindromic repeat (CRISPR)/Cas-based RNA-guided DNA endonucleases. However, off-target effects are still the major issue in genome editing, and limit the application in gene therapy. Here, we summarized the cause and compared different detection methods of off-targets.

The Law and the Teacher in Missouri--A Handbook for Teachers, Administrators, and School Board Members. Third Edition.

ERIC Educational Resources Information Center

Garber, Lee O.; Delon, Floyd G.

This book is designed to acquaint Missouri teachers with the state laws that affect them. Teachers' legal status, their rights, duties, and obligations are defined. Examples are taken from constitutional provisions, judicial decisions, and statutory enactments to show both general aspects of school law for all teachers and specific applications to…

Diesel Technology: Safety Skills. [Teacher and Student Editions.

ERIC Educational Resources Information Center

Kellum, Mary

Competency-based teacher and student materials are provided for three units on safety skills as part of a diesel technology curriculum. The units cover the following topics: general safety; workplace safety; and first aid. The materials are based on the curriculum-alignment concept of first stating the objectives, then developing instructional…

Environmental Involvement. . . A Teacher's Guide (2nd Edition).

ERIC Educational Resources Information Center

1971

Presented in this teacher's guide are ideas and projects to help students develop an awareness and appreciation of their environment. Sharpening the senses is emphasized through activities dealing with water quality, sound qualities, and noise, air quality, solid waste control, and soil management. The text is divided into four levels roughly…

Science on TeacherTube: A Mixed Methods Analysis of Teacher Produced Video

NASA Astrophysics Data System (ADS)

Chmiel, Margaret (Marjee)

Increased bandwidth, inexpensive video cameras and easy-to-use video editing software have made social media sites featuring user generated video (UGV) an increasingly popular vehicle for online communication. As such, UGV have come to play a role in education, both formal and informal, but there has been little research on this topic in scholarly literature. In this mixed-methods study, a content and discourse analysis are used to describe the most successful UGV in the science channel of an education-focused site called TeacherTube. The analysis finds that state achievement tests, and their focus on vocabulary and recall-level knowledge, drive much of the content found on TeacherTube.

Foreign Language Teaching in Rudolf Steiner Schools. Guidelines for Class-Teachers and Language Teachers. First Edition.

ERIC Educational Resources Information Center

Stott, Michael

This book is intended for foreign language teachers interested in the approaches used in Rudolf Steiner schools, and also classroom teachers who teach foreign languages. Chapters address these issues: what the language lesson is to achieve; how the language lesson differs from other lessons; lesson design; examples of actual lessons; avoiding the…

Genome editing comes of age.

PubMed

Kim, Jin-Soo

2016-09-01

Genome editing harnesses programmable nucleases to cut and paste genetic information in a targeted manner in living cells and organisms. Here, I review the development of programmable nucleases, including zinc finger nucleases (ZFNs), TAL (transcription-activator-like) effector nucleases (TALENs) and CRISPR (cluster of regularly interspaced palindromic repeats)-Cas9 (CRISPR-associated protein 9) RNA-guided endonucleases (RGENs). I specifically highlight the key advances that set the foundation for the rapid and widespread implementation of CRISPR-Cas9 genome editing approaches that has revolutionized the field.

The Market System: Does It Work? Teacher's Edition.

ERIC Educational Resources Information Center

O'Neill, James B.

This document is the teacher's guide for SO 008 864. Developed for secondary students, the materials aid students in the understanding of the United States economic system. Along with the narrative found in the student materials, the guide presents objectives, concepts, procedures, and evaluation for completing the unit. The materials are arranged…

45 CFR 73.735-705 - Writing and editing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... different wording is approved by the Assistant General Counsel, Business and Administrative Law Division... duties; (This includes editing for scientific or professional journals which is related to his or her official duties.) (3) Material is written or edited which pertains to any Government-sponsored research or...

Teaching for Understanding: What It Is and How to Do It. 2nd Edition

ERIC Educational Resources Information Center

Newton, Douglas P.

2011-01-01

At a time when league tables can be everything, examination grades matter. Perhaps more than many would admit, the cost is a lack of understanding. The new edition of this book provides practical advice about how to support understanding in both children and adults. It is for all teachers and lecturers, experienced or otherwise, who want learners…

Teacher Negotiations and Solutions to Impasse.

ERIC Educational Resources Information Center

Rollins, Sidney P., Ed.

This document contains edited presentations given during a conference on teacher negotiations and solutions to impasse in Rhode Island. The principal speakers were Henry J. Nardone, chairman of the Elementary and Secondary Education Sub-Committee of the Board of Regents; Julius C. Michaelson, Attorney General for Rhode Island; and Dr. Peter…

Introduction to Agricultural Products and Processing. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This document consists of the teacher's guide to a module designed to teach high school students entry-level job competencies in the new areas of agriculture that are now emerging. The module, one of a series of publications designed to identify these new competencies, contains 11 instructional units that cover the following topics: trends in…

C-to-U editing and site-directed RNA editing for the correction of genetic mutations.

PubMed

Vu, Luyen Thi; Tsukahara, Toshifumi

2017-07-24

Cytidine to uridine (C-to-U) editing is one type of substitutional RNA editing. It occurs in both mammals and plants. The molecular mechanism of C-to-U editing involves the hydrolytic deamination of a cytosine to a uracil base. C-to-U editing is mediated by RNA-specific cytidine deaminases and several complementation factors, which have not been completely identified. Here, we review recent findings related to the regulation and enzymatic basis of C-to-U RNA editing. More importantly, when C-to-U editing occurs in coding regions, it has the power to reprogram genetic information on the RNA level, therefore it has great potential for applications in transcript repair (diseases related to thymidine to cytidine (T>C) or adenosine to guanosine (A>G) point mutations). If it is possible to manipulate or mimic C-to-U editing, T>C or A>G genetic mutation-related diseases could be treated. Enzymatic and non-enzymatic site-directed RNA editing are two different approaches for mimicking C-to-U editing. For enzymatic site-directed RNA editing, C-to-U editing has not yet been successfully performed, and in theory, adenosine to inosine (A-to-I) editing involves the same strategy as C-to-U editing. Therefore, in this review, for applications in transcript repair, we will provide a detailed overview of enzymatic site-directed RNA editing, with a focus on A-to-I editing and non-enzymatic site-directed C-to-U editing.

Meeting Special Educational Needs in Primary Classrooms: Inclusion and How to Do It. 2nd Edition

ERIC Educational Resources Information Center

Briggs, Sue

2016-01-01

There are greater numbers of children with Special Educational Needs and Disabilities (SEND) now attending mainstream schools. This fully updated and revised edition of "Meeting Special Educational Needs in Primary Classrooms" is written by an experienced teacher, adviser and SEN consultant and explains the challenges that these children…

The Humanities: A Selective Guide to Information Sources. Fifth Edition. Library and Information Science Text Series.

ERIC Educational Resources Information Center

Blazek, Ron; Aversa, Elizabeth

This book provides a guide to humanities information sources for teachers and students in schools of library and information science, reference librarians, collection development officers in libraries, humanities scholars, and others who have information needs in the broad discipline. This fifth edition represents a more comprehensive and updated…

International Education: Values and Perspectives on...Four Human Rights. Teacher Edition.

ERIC Educational Resources Information Center

American Federation of Teachers, Washington, DC.

This handbook is for use in teacher center or school district inservice programs designed to raise the levels of teacher interest, understanding, and involvement in incorporating international education into the curricula of the public schools. The introduction in the first section provides background information on the use of the guide and…

Star Trek with Latin. Teacher's Guide. Tentative Edition.

ERIC Educational Resources Information Center

Masciantonio, Rudolph; And Others

The purpose of this guide is to assist Latin and English teachers with some background in Latin to expand the English vocabulary and reading skills of students through the study of Latin roots, prefixes, and suffixes. The introductory material in the guide provides general notes on the teaching of Latin in the Philadelphia School District,…

Traffic Flow. USMES Teacher's Resource Book, Preliminary Edition.

ERIC Educational Resources Information Center

Education Development Center, Inc., Newton, MA.

This USMES unit challenges students to recommend and try to have a new road design or a system for rerouting traffic accepted so that cars and trucks can move safely at a reasonable speed through a busy intersection near the school. The teacher resource book for the Traffic Flow unit contains five sections. The first section describes the USMES…

Middle School Teachers' Strategies for Including Overweight Students in Skill and Fitness Instruction

ERIC Educational Resources Information Center

Rukavina, Paul B.; Doolittle, Sarah; Li, Weidong; Manson, Mara; Beale, Angela

2015-01-01

As part of a larger study, this paper describes teachers' perspectives and strategies on including overweight and obese students (OWS) in instruction related to motor skill/game play and fitness development in physical education. Using the Social Ecological Constraints framework, a qualitative multicase study was conducted using multiple in-depth…

Reaching and Teaching Students in Poverty: Strategies for Erasing the Opportunity Gap. Second Edition. Multicultural Education Series

ERIC Educational Resources Information Center

Gorski, Paul C.

2017-01-01

This influential book describes the knowledge and skills teachers and school administrators need to recognize and combat bias and inequity that undermine educational engagement for students experiencing poverty. The Second Edition features two new chapters--"Embracing a Structural View of Poverty and Education: Ditching Deficit Ideology and…

Educating Everybody's Children: Diverse Teaching Strategies for Diverse Learners, Revised and Expanded 2nd Edition

ERIC Educational Resources Information Center

Cole, Robert W.

2008-01-01

Since its first publication in 1995, hundreds of thousands of teachers in every grade and subject have benefited from this landmark guide on how to teach students from economically, ethnically, culturally, and linguistically diverse groups. Now at last, this all-new and expanded edition--nearly twice the size of the original--explains how these…

Adeno-associated virus inverted terminal repeats stimulate gene editing.

PubMed

Hirsch, M L

2015-02-01

Advancements in genome editing have relied on technologies to specifically damage DNA which, in turn, stimulates DNA repair including homologous recombination (HR). As off-target concerns complicate the therapeutic translation of site-specific DNA endonucleases, an alternative strategy to stimulate gene editing based on fragile DNA was investigated. To do this, an episomal gene-editing reporter was generated by a disruptive insertion of the adeno-associated virus (AAV) inverted terminal repeat (ITR) into the egfp gene. Compared with a non-structured DNA control sequence, the ITR induced DNA damage as evidenced by increased gamma-H2AX and Mre11 foci formation. As local DNA damage stimulates HR, ITR-mediated gene editing was investigated using DNA oligonucleotides as repair substrates. The AAV ITR stimulated gene editing >1000-fold in a replication-independent manner and was not biased by the polarity of the repair oligonucleotide. Analysis of additional human DNA sequences demonstrated stimulation of gene editing to varying degrees. In particular, inverted yet not direct, Alu repeats induced gene editing, suggesting a role for DNA structure in the repair event. Collectively, the results demonstrate that inverted DNA repeats stimulate gene editing via double-strand break repair in an episomal context and allude to efficient gene editing of the human chromosome using fragile DNA sequences.

Reliability and Validity of the Early Childhood Environment Rating Scale, Revised Edition, ECERS-R in Arabic

ERIC Educational Resources Information Center

Hadeed, Julie

2014-01-01

The aim of this study was to test reliabilities and validations for the Arabic translation of the Early Childhood Environment Rating Scale, Revised (ECERS-R) scale [Harms, T., Clifford, R. M., & Cryer, D. (1998). "Early childhood environment rating scale, revised edition." New York: Teachers College Press]. ECERS-R mean scores were…

Creative Sciencing. Ideas and Activities for Teachers and Children. Grades K-6. Third Edition.

ERIC Educational Resources Information Center

De Vito, Alfred; Krockover, Gerald H.

This resource book includes 163 science activities for both preservice and in-service teachers. Activities have been field-tested and are cross-referenced according to the processes of science and the content area covered. Each activity has been written to evoke ideas from the reader, thus enabling each activity to serve a base for additional…

Genome editing via delivery of Cas9 ribonucleoprotein.

PubMed

DeWitt, Mark A; Corn, Jacob E; Carroll, Dana

2017-05-15

The CRISPR-Cas genome editing system is very powerful. The format of the CRISPR reagents and the means of delivery are often important factors in targeting efficiency. Delivery of recombinant Cas9 protein and guide RNA (gRNA) as a preformed ribonucleoprotein (RNP) complex has recently emerged as a powerful and general approach to genome editing. Here we outline methods to produce and deliver Cas9 RNPs. A donor DNA carrying desired sequence changes can also be included to program precise sequence introduction or replacement. RNP delivery limits exposure to genome editing reagents, reduces off-target events, drives high rates of homology-dependent repair, and can be applied to embryos to rapidly generate animal models. RNP delivery thus minimizes some of the pitfalls of alternative editing modalities and is rapidly being adopted by the genome editing community. Copyright © 2017 Elsevier Inc. All rights reserved.

Behavior Management Strategies for Teachers: Achieving Instructional Effectiveness, Student Success, and Student Motivation--Every Teacher and Any Student Can! 2nd Edition.

ERIC Educational Resources Information Center

Harlan, Joan C.; Rowland, Sidney T.

This book provides tested methods for teachers to use in their behavior management and instructional efforts, offering strategies for maintaining and increasing appropriate behaviors as well as preventing and remediating inappropriate behaviors. Section 1, "Understanding Behavior and Selected Models," includes (1) "Understanding…

ExpEdit: a webserver to explore human RNA editing in RNA-Seq experiments.

PubMed

Picardi, Ernesto; D'Antonio, Mattia; Carrabino, Danilo; Castrignanò, Tiziana; Pesole, Graziano

2011-05-01

ExpEdit is a web application for assessing RNA editing in human at known or user-specified sites supported by transcript data obtained by RNA-Seq experiments. Mapping data (in SAM/BAM format) or directly sequence reads [in FASTQ/short read archive (SRA) format] can be provided as input to carry out a comparative analysis against a large collection of known editing sites collected in DARNED database as well as other user-provided potentially edited positions. Results are shown as dynamic tables containing University of California, Santa Cruz (UCSC) links for a quick examination of the genomic context. ExpEdit is freely available on the web at http://www.caspur.it/ExpEdit/.

Genome editing systems in novel therapies.

PubMed

Jang, Yoon-Young; Cai, Liuhong; Ye, Zhaohui

2016-01-01

Genome editing is the process in which DNA sequences at precise genomic locations are modified. In the past three decades, genome editing by homologous recombination has been successfully performed in mouse for generating genetic models. The low efficiency of this process in human cells, however, had prevented its clinical application until the recent advancements in designer endonuclease technologies. The significantly improved genome editing efficiencies aided by ZFN, TALEN, and CRISPR systems provide unprecedented opportunities not only for biomedical research, but also for developing novel therapies. Applications based on these genome editing tools to disrupt deleterious genes, correct genetic mutations, deliver functional transgenes more effectively or even modify the epigenetic landscape are being actively investigated for gene and cell therapy purposes. Encouraging results have been obtained in limited clinical trials in the past two years. While most of the applications are still in proof-of-principle or preclinical development stages, it is anticipated that the coming years will see increasing clinical success in novel therapies based on the modern genome editing technologies. It should be noted that critical issues still remain before the technologies can be translated into more reliable therapies. These key issues include off-target evaluation, establishing appropriate preclinical models and improving the currently low efficiency of homology-based precise gene replacement. In this review we discuss the preclinical and clinical studies aiming at translating the genome editing technologies as well as the issues that are important for more successful translation.

Therapeutic gene editing: delivery and regulatory perspectives.

PubMed

Shim, Gayong; Kim, Dongyoon; Park, Gyu Thae; Jin, Hyerim; Suh, Soo-Kyung; Oh, Yu-Kyoung

2017-06-01

Gene-editing technology is an emerging therapeutic modality for manipulating the eukaryotic genome by using target-sequence-specific engineered nucleases. Because of the exceptional advantages that gene-editing technology offers in facilitating the accurate correction of sequences in a genome, gene editing-based therapy is being aggressively developed as a next-generation therapeutic approach to treat a wide range of diseases. However, strategies for precise engineering and delivery of gene-editing nucleases, including zinc finger nucleases, transcription activator-like effector nuclease, and CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats-associated nuclease Cas9), present major obstacles to the development of gene-editing therapies, as with other gene-targeting therapeutics. Currently, viral and non-viral vectors are being studied for the delivery of these nucleases into cells in the form of DNA, mRNA, or proteins. Clinical trials are already ongoing, and in vivo studies are actively investigating the applicability of CRISPR/Cas9 techniques. However, the concept of correcting the genome poses major concerns from a regulatory perspective, especially in terms of safety. This review addresses current research trends and delivery strategies for gene editing-based therapeutics in non-clinical and clinical settings and considers the associated regulatory issues.

Therapeutic gene editing: delivery and regulatory perspectives

PubMed Central

Shim, Gayong; Kim, Dongyoon; Park, Gyu Thae; Jin, Hyerim; Suh, Soo-Kyung; Oh, Yu-Kyoung

2017-01-01

Gene-editing technology is an emerging therapeutic modality for manipulating the eukaryotic genome by using target-sequence-specific engineered nucleases. Because of the exceptional advantages that gene-editing technology offers in facilitating the accurate correction of sequences in a genome, gene editing-based therapy is being aggressively developed as a next-generation therapeutic approach to treat a wide range of diseases. However, strategies for precise engineering and delivery of gene-editing nucleases, including zinc finger nucleases, transcription activator-like effector nuclease, and CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats-associated nuclease Cas9), present major obstacles to the development of gene-editing therapies, as with other gene-targeting therapeutics. Currently, viral and non-viral vectors are being studied for the delivery of these nucleases into cells in the form of DNA, mRNA, or proteins. Clinical trials are already ongoing, and in vivo studies are actively investigating the applicability of CRISPR/Cas9 techniques. However, the concept of correcting the genome poses major concerns from a regulatory perspective, especially in terms of safety. This review addresses current research trends and delivery strategies for gene editing-based therapeutics in non-clinical and clinical settings and considers the associated regulatory issues. PMID:28392568

CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_TRMM-PFM_Edition1)

NASA Technical Reports Server (NTRS)

Wielicki, Bruce A. (Principal Investigator)

Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2000-12-31] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

Genome Editing of Monogenic Neuromuscular Diseases: A Systematic Review.

PubMed

Long, Chengzu; Amoasii, Leonela; Bassel-Duby, Rhonda; Olson, Eric N

2016-11-01

Muscle weakness, the most common symptom of neuromuscular disease, may result from muscle dysfunction or may be caused indirectly by neuronal and neuromuscular junction abnormalities. To date, more than 780 monogenic neuromuscular diseases, linked to 417 different genes, have been identified in humans. Genome-editing methods, especially the CRISPR (clustered regularly interspaced short palindromic repeats)-Cas9 (CRISPR-associated protein 9) system, hold clinical potential for curing many monogenic disorders, including neuromuscular diseases such as Duchenne muscular dystrophy, spinal muscular atrophy, amyotrophic lateral sclerosis, and myotonic dystrophy type 1. To provide an overview of genome-editing approaches; to summarize published reports on the feasibility, efficacy, and safety of current genome-editing methods as they relate to the potential correction of monogenic neuromuscular diseases; and to highlight scientific and clinical opportunities and obstacles toward permanent correction of disease-causing mutations responsible for monogenic neuromuscular diseases by genome editing. PubMed and Google Scholar were searched for articles published from June 30, 1989, through June 9, 2016, using the following keywords: genome editing, CRISPR-Cas9, neuromuscular disease, Duchenne muscular dystrophy, spinal muscular atrophy, amyotrophic lateral sclerosis, and myotonic dystrophy type 1. The following sources were reviewed: 341 articles describing different approaches to edit mammalian genomes; 330 articles describing CRISPR-Cas9-mediated genome editing in cell culture lines (in vitro) and animal models (in vivo); 16 websites used to generate single-guide RNA; 4 websites for off-target effects; and 382 articles describing viral and nonviral delivery systems. Articles describing neuromuscular diseases, including Duchenne muscular dystrophy, spinal muscular atrophy, amyotrophic lateral sclerosis, and myotonic dystrophy type 1, were also reviewed. Multiple proof

Solar Physics and Terrestrial Effects: A Curriculum Guide for Teachers Grades 7-12, 2nd Edition.

ERIC Educational Resources Information Center

Briggs, Roger P.; Carlisle, Robert J.

This curriculum guide includes a brief textbook, a hands-on activity guide, and resource listings. The textbook provides background information in solar physics for teachers and contains problems suitable for advanced students at the end of each chapter. Topics covered in the textbook include stellar evolution, the structure of the sun, methods of…

Comparing Levels of Professional Satisfaction in Preschool Teachers Whose Classes Include or Do Not Include a Special-Needs Student

ERIC Educational Resources Information Center

Koyutürk, Nazife; Sahbaz, Ümit

2015-01-01

The purpose of this study is to compare the professional satisfaction of the preschool teachers in whose class there is a student with special needs to the preschool teachers in whose class there are not any students with special needs. The research study group was composed of 185 pre-school teachers who work in the city and county center in…

The clinical applications of genome editing in HIV.

PubMed

Wang, Cathy X; Cannon, Paula M

2016-05-26

HIV/AIDS has long been at the forefront of the development of gene- and cell-based therapies. Although conventional gene therapy approaches typically involve the addition of anti-HIV genes to cells using semirandomly integrating viral vectors, newer genome editing technologies based on engineered nucleases are now allowing more precise genetic manipulations. The possible outcomes of genome editing include gene disruption, which has been most notably applied to the CCR5 coreceptor gene, or the introduction of small mutations or larger whole gene cassette insertions at a targeted locus. Disruption of CCR5 using zinc finger nucleases was the first-in-human application of genome editing and remains the most clinically advanced platform, with 7 completed or ongoing clinical trials in T cells and hematopoietic stem/progenitor cells (HSPCs). Here we review the laboratory and clinical findings of CCR5 editing in T cells and HSPCs for HIV therapy and summarize other promising genome editing approaches for future clinical development. In particular, recent advances in the delivery of genome editing reagents and the demonstration of highly efficient homology-directed editing in both T cells and HSPCs are expected to spur the development of even more sophisticated applications of this technology for HIV therapy. © 2016 by The American Society of Hematology.

Me and My Environment, Unit V: Air and Water in My Environment, Experimental Edition 1973-74.

ERIC Educational Resources Information Center

Biological Sciences Curriculum Study, Boulder, CO.

The experimental 1973-74 edition of Unit V consists of 35 life science curriculum activities intended for 13- to 16-year-old educable mentally handicapped adolescents. The role of the teacher in continuing field trials is noted and environmental themes and elements, inquiry skills, problem solving skills, and applicational behaviors and attitudes…

Kids Included through Technology Are Enriched: A Guidebook for Teachers of Young Children.

ERIC Educational Resources Information Center

Carlson, Brenda; Samels, Karen

This guidebook is designed to provide information on technology to teachers and service providers who work with children with special needs. It may also be helpful for parents and caregivers of young children. Topics include: (1) the definition of assistive technology; (2) the philosophy of using technology with young children and a rationale that…

Helping Children through Books: A Selected Booklist. Third Revised Edition.

ERIC Educational Resources Information Center

Pearl, Patricia

An update of a bibliotherapy bibliography compiled by the Church and Synagogue Library Association (CSLA) a decade ago, this list includes books intended for children from a preschool to a sixth-grade reading level. Although the first edition included works concerning religion, this edition does not, since those works are already covered in other…

A Subdivision-Based Representation for Vector Image Editing.

PubMed

Liao, Zicheng; Hoppe, Hugues; Forsyth, David; Yu, Yizhou

2012-11-01

Vector graphics has been employed in a wide variety of applications due to its scalability and editability. Editability is a high priority for artists and designers who wish to produce vector-based graphical content with user interaction. In this paper, we introduce a new vector image representation based on piecewise smooth subdivision surfaces, which is a simple, unified and flexible framework that supports a variety of operations, including shape editing, color editing, image stylization, and vector image processing. These operations effectively create novel vector graphics by reusing and altering existing image vectorization results. Because image vectorization yields an abstraction of the original raster image, controlling the level of detail of this abstraction is highly desirable. To this end, we design a feature-oriented vector image pyramid that offers multiple levels of abstraction simultaneously. Our new vector image representation can be rasterized efficiently using GPU-accelerated subdivision. Experiments indicate that our vector image representation achieves high visual quality and better supports editing operations than existing representations.

The Marginal Teacher: A Step-by-Step Guide to Fair Procedures for Identification and Dismissal

ERIC Educational Resources Information Center

Lawrence, C. Edward

2005-01-01

This third edition offers timely solutions for successfully dealing with marginal teachers. Lawrence illustrates the proper actions that principals should integrate into the evaluation processes to successfully gather documentation to help improve or terminate an ineffective teacher. Complete with tools and resources to streamline the evaluation…

Handbook of ecotoxicology, second edition

USGS Publications Warehouse

Hoffman, David J.; Rattner, Barnett A.; Burton, G. Allen; Cairns, John

2003-01-01

Handbook of Ecotoxicology, Second Edition focuses on toxic substances and how they affect ecosystems worldwide. It presents methods for quantifying and measuring ecotoxicological effects in the field and in the lab, as well as methods for estimating, predicting, and modeling in ecotoxicology studies. Completely revised and updated with 18 new chapters, this second edition includes contributions from over 75 international experts. Also, a Technical Review Board reviewed all manuscripts for accuracy and currency. This authoritative work is the definitive reference for students, researchers, consultants, and other professionals in the environmental sciences, toxicology, chemistry, biology, and ecology - in academia, industry, and government.

The Monthly Sky Guide: Sixth Edition

NASA Astrophysics Data System (ADS)

Ridpath, Ian; Tirion, Wil

2003-06-01

The latest edition of Ian Ridpath and Wil Tirion's popular guide to the night sky is updated for planet positions and forthcoming eclipses up to the end of the year 2007. With one chapter for each month of the year, this is an easy-to-use handbook for anyone wanting to identify constellations, star clusters, nebulae, to plot the movement of planets, or witness solar and lunar eclipses. Most of the features discussed are visible to the naked eye and all can be seen with a small telescope or binoculars. Ian Ridpath has been a full-time writer, broadcaster and lecturer on astronomy and space for more than twenty-five years. He has written and edited more than 40 books, including A Comet Called Haley (Cambridge, 1985). Wil Tirion made his first star map in 1977. It showed stars to the magnitude of 6.5 and was issued as a set of maps by the British Astronomical Association in 1981. He has illustrated numerous books and magazines, including The Cambridge Star Atlas (Cambridge, 2001). Previous Edition Pb (1999): 0-521-66771-2

Advanced Digital Imaging Laboratory Using MATLAB® (Second edition)

NASA Astrophysics Data System (ADS)

Yaroslavsky, Leonid P.

2016-09-01

The first edition of this text book focussed on providing practical hands-on experience in digital imaging techniques for graduate students and practitioners keeping to a minimum any detailed discussion on the underlying theory. In this new extended edition, the author builds on the strength of the original edition by expanding the coverage to include formulation of the major theoretical results that underlie the exercises as well as introducing numerous modern concepts and new techniques. Whether you are studying or already using digital imaging techniques, developing proficiency in the subject is not possible without mastering practical skills. Including more than 100 MATLAB® exercises, this book delivers a complete applied course in digital imaging theory and practice. Part of IOP Series in Imaging Engineering Supplementary MATLAB codes and data files are available within Book Information.

The Examination of Physical Education Teachers' Perceptions of Their Teacher Training to Include Students with Disabilities in General Physical Education

ERIC Educational Resources Information Center

Townsend, Amy

2017-01-01

Despite legislative mandates, only 32% of states require specific licensure in adapted physical education (APE); consequently, general physical educators are challenged with including students with disabilities into regular classrooms. Although physical education teachers are considered qualified personnel to teach students with disabilities in…

Regulatory factors governing adenosine-to-inosine (A-to-I) RNA editing.

PubMed

Hong, HuiQi; Lin, Jaymie Siqi; Chen, Leilei

2015-03-31

Adenosine-to-inosine (A-to-I) RNA editing, the most prevalent mode of transcript modification in higher eukaryotes, is catalysed by the adenosine deaminases acting on RNA (ADARs). A-to-I editing imposes an additional layer of gene regulation as it dictates various aspects of RNA metabolism, including RNA folding, processing, localization and degradation. Furthermore, editing events in exonic regions contribute to proteome diversity as translational machinery decodes inosine as guanosine. Although it has been demonstrated that dysregulated A-to-I editing contributes to various diseases, the precise regulatory mechanisms governing this critical cellular process have yet to be fully elucidated. However, integration of previous studies revealed that regulation of A-to-I editing is multifaceted, weaving an intricate network of auto- and transregulations, including the involvement of virus-originated factors like adenovirus-associated RNA. Taken together, it is apparent that tipping of any regulatory components will have profound effects on A-to-I editing, which in turn contributes to both normal and aberrant physiological conditions. A complete understanding of this intricate regulatory network may ultimately be translated into new therapeutic strategies against diseases driven by perturbed RNA editing events. Herein, we review the current state of knowledge on the regulatory mechanisms governing A-to-I editing and propose the role of other co-factors that may be involved in this complex regulatory process.

The Case for Expanding Standards for Teacher Evaluation to Include an Instructional Supervision Perspective

ERIC Educational Resources Information Center

Holland, Patricia

2005-01-01

Despite the concerns of scholars in the field of instructional supervision, teacher evaluations continue to emphasize bureaucratic accountability and standardization. This article presents an argument for extending the Joint Committee on Standards' Personnel Evaluation Standards to include standards related to the practice of supervision. The…

Can You Tube It? Providing Chemistry Teachers with Technological Tools and Enhancing Their Self-Efficacy Beliefs

ERIC Educational Resources Information Center

Blonder, Ron; Jonatan, Moshe; Bar-Dov, Ziva; Benny, Naama; Rap, Shelley; Sakhnini, Sohair

2013-01-01

The goal of this research was to examine the change in the skills, Technological Pedagogical Content Knowledge (TPACK) and self-efficacy beliefs of chemistry teachers regarding video editing and using YouTube videos in high-school chemistry lessons, as a result of a professional development program that focused on editing YouTube videos and the…

Modern Genome Editing Technologies in Huntington's Disease Research.

PubMed

Malankhanova, Tuyana B; Malakhova, Anastasia A; Medvedev, Sergey P; Zakian, Suren M

2017-01-01

The development of new revolutionary technologies for directed gene editing has made it possible to thoroughly model and study NgAgo human diseases at the cellular and molecular levels. Gene editing tools like ZFN, TALEN, CRISPR-based systems, NgAgo and SGN can introduce different modifications. In gene sequences and regulate gene expression in different types of cells including induced pluripotent stem cells (iPSCs). These tools can be successfully used for Huntington's disease (HD) modeling, for example, to generate isogenic cell lines bearing different numbers of CAG repeats or to correct the mutation causing the disease. This review presents common genome editing technologies and summarizes the progress made in using them in HD and other hereditary diseases. Furthermore, we will discuss prospects and limitations of genome editing in understanding HD pathology.

34 CFR 611.2 - What management plan must be included in a Teacher Quality Enhancement Grants Program application?

Code of Federal Regulations, 2010 CFR

2010-07-01

... TEACHER QUALITY ENHANCEMENT GRANTS PROGRAM General Provisions § 611.2 What management plan must be... 34 Education 3 2010-07-01 2010-07-01 false What management plan must be included in a Teacher Quality Enhancement Grants Program application? 611.2 Section 611.2 Education Regulations of the Offices...

2015 Edition Health Information Technology (Health IT) Certification Criteria, 2015 Edition Base Electronic Health Record (EHR) Definition, and ONC Health IT Certification Program Modifications. Final rule.

PubMed

2015-10-16

This final rule finalizes a new edition of certification criteria (the 2015 Edition health IT certification criteria or "2015 Edition'') and a new 2015 Edition Base Electronic Health Record (EHR) definition, while also modifying the ONC Health IT Certification Program to make it open and accessible to more types of health IT and health IT that supports various care and practice settings. The 2015 Edition establishes the capabilities and specifies the related standards and implementation specifications that Certified Electronic Health Record Technology (CEHRT) would need to include to, at a minimum, support the achievement of meaningful use by eligible professionals (EPs), eligible hospitals, and critical access hospitals (CAHs) under the Medicare and Medicaid EHR Incentive Programs (EHR Incentive Programs) when such edition is required for use under these programs.

Development of the promoting teacher attribution model for promoting science teachers' moral and ethical characteristics

NASA Astrophysics Data System (ADS)

Chanprathak, Anusorn; Worakham, Paisan; Suikraduang, Arun

2018-01-01

The promotion science teacher attribution model to develop the moral and ethical characteristics was to analyze, synthesis, and develop the guidelines of the scoping study into concepts, theories and research related about the moral and ethics of characteristically teachers from the resources, including research papers, research articles related research, and interviews with luminaries of 9 members. Using interviews and document analysis, data analysis, content analysis, and present an essay was built. The promoting attributes a teacher, moral principles, concepts and theories involved and guidance of a qualified were developed. The Multiple-Attribute Consensus Reaching (MACR) from 12 educational experts were checked the suitability and feasibility of the model, the possibility of the manual with the research instruments consisted of the promotion model attributes the moral and ethics teacher's characteristics were evaluated, to guide the promotion attributes' model forms were assessed, the first edition of the manual data analysis, information obtained from the evaluation of the suitability and feasibility analysis model and guide for the average were administered. The results have found that; the promoting moral teacher attribute data to their moral and ethical characteristics was divided into two groups, priests and scholars. In both groups, the promotion attributes, focusing on teacher's groups is moral in nature to modify the idea to a change of attitude within the organism. Students got down to real experience; an analysis and synthesis face learning environments that cause cognitive skills to act as a self-realization possibly. The promotion model, moral principles, including the importance of the activities, objectives and evaluation methods were attributed. These core concepts learning theory and social cognitive theory, and integrated learning experience were comprised in five stages and four processes, namely; the intended, memory storage process, the

Re-editing the paradigm of Cytidine (C) to Uridine (U) RNA editing.

PubMed

Fossat, Nicolas; Tam, Patrick P L

2014-01-01

Cytidine (C) to Uridine (U) RNA editing is a post-trancriptional modification that until recently was known to only affect Apolipoprotein b (Apob) RNA and minimally require 2 components of the C to U editosome, the deaminase APOBEC1 and the RNA-binding protein A1CF. Our latest work has identified a novel RNA-binding protein, RBM47, as a core component of the editosome, which can substitute A1CF for the editing of ApoB mRNA. In addition, new RNA species that are subjected to C to U editing have been identified. Here, we highlight these recent discoveries and discuss how they change our view of the composition of the C to U editing machinery and expand our knowledge of the functional attributes of C to U RNA editing.

CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_Terra-FM1_Edition1)

NASA Technical Reports Server (NTRS)

Wielicki, Bruce A. (Principal Investigator)

Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2005-11-02] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_Aqua-FM4_Edition1)

NASA Technical Reports Server (NTRS)

Wielicki, Bruce A. (Principal Investigator)

Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2005-04-02] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_Terra-FM2_Edition2)

NASA Technical Reports Server (NTRS)

Wielicki, Bruce A. (Principal Investigator)

Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2006-01-01] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_Aqua-FM3_Edition1)

NASA Technical Reports Server (NTRS)

Wielicki, Bruce A. (Principal Investigator)

Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2005-11-02] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_Aqua-FM4_Edition2)

NASA Technical Reports Server (NTRS)

Wielicki, Bruce A. (Principal Investigator)

Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2005-03-29] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_Aqua-FM3_Edition2)

NASA Technical Reports Server (NTRS)

Wielicki, Bruce A. (Principal Investigator)

Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2006-01-01] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

Convergent Validity with the BERS-2 Teacher Rating Scale and the Achenbach Teacher's Report Form: A Replication and Extension

ERIC Educational Resources Information Center

Benner, Gregory J.; Beaudoin, Kathleen; Mooney, Paul; Uhing, Brad M.; Pierce, Corey D.

2008-01-01

In the present study, we sought to extend instrument validation research for a strength-based emotional and behavior rating scale, the "Teacher Rating Scale of the Behavior and Emotional Rating Scale-Second Edition" (BERS-2; Epstein, M. H. (2004). "Behavioral and emotional rating scale" (2nd ed.). Austin, TX: PRO-ED) through…

Your Reading: An Annotated Booklist for Middle School and Junior High. 11th Edition. NCTE Bibliography Series.

ERIC Educational Resources Information Center

Brown, Jean E., Ed.; Stephens, Elaine C., Ed.

Organized around the theme of "challenges," the 11th edition of "Your Reading" offers annotations of more than 1,200 books for young adults. Intended for teachers, librarians, parents, and students, this booklist presents recently published books that can be read for many purposes--for sheer enjoyment of the story, to pique…

The Effects of the Mississippi Curriculum Test: Second Edition: A Study on the Teacher Morale and Teacher Efficacy of Seventh and Eighth Grade Teachers

ERIC Educational Resources Information Center

Willis, Mario

2014-01-01

The primary purpose of this study was to examine the effects that high-stakes tests have on middle school teachers' morale and teachers' efficacy in the state of Mississippi. The participants in this study were teachers in the areas of language arts, mathematics, and science at the middle school level. The researcher used a correlational design,…

Ebola virus RNA editing depends on the primary editing site sequence and an upstream secondary structure.

PubMed

Mehedi, Masfique; Hoenen, Thomas; Robertson, Shelly; Ricklefs, Stacy; Dolan, Michael A; Taylor, Travis; Falzarano, Darryl; Ebihara, Hideki; Porcella, Stephen F; Feldmann, Heinz

2013-01-01

Ebolavirus (EBOV), the causative agent of a severe hemorrhagic fever and a biosafety level 4 pathogen, increases its genome coding capacity by producing multiple transcripts encoding for structural and nonstructural glycoproteins from a single gene. This is achieved through RNA editing, during which non-template adenosine residues are incorporated into the EBOV mRNAs at an editing site encoding for 7 adenosine residues. However, the mechanism of EBOV RNA editing is currently not understood. In this study, we report for the first time that minigenomes containing the glycoprotein gene editing site can undergo RNA editing, thereby eliminating the requirement for a biosafety level 4 laboratory to study EBOV RNA editing. Using a newly developed dual-reporter minigenome, we have characterized the mechanism of EBOV RNA editing, and have identified cis-acting sequences that are required for editing, located between 9 nt upstream and 9 nt downstream of the editing site. Moreover, we show that a secondary structure in the upstream cis-acting sequence plays an important role in RNA editing. EBOV RNA editing is glycoprotein gene-specific, as a stretch encoding for 7 adenosine residues located in the viral polymerase gene did not serve as an editing site, most likely due to an absence of the necessary cis-acting sequences. Finally, the EBOV protein VP30 was identified as a trans-acting factor for RNA editing, constituting a novel function for this protein. Overall, our results provide novel insights into the RNA editing mechanism of EBOV, further understanding of which might result in novel intervention strategies against this viral pathogen.

Forestry. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This curriculum is designed to provide training in skills used by technicians and foresters throughout the world who plant, care for, and harvest trees. It contains 16 units. Each instructional unit includes some or all of the basic components of a unit of instruction: performance objectives, suggested activities, handouts, information sheets,…

In Search of the Eco-Teacher: Public School Edition

ERIC Educational Resources Information Center

Blenkinsop, Sean

2014-01-01

This paper uses an innovative building-less Canadian public elementary school and its accompanying large-scale research project to consider the characteristics that might be required of a teacher interested in working in an emergent, environmental, place- and community-based experiential public school setting. The six characteristics considered…

Genome editing in livestock: Are we ready for a revolution in animal breeding industry?

PubMed

Ruan, Jinxue; Xu, Jie; Chen-Tsai, Ruby Yanru; Li, Kui

2017-12-01

Genome editing is a powerful technology that can efficiently alter the genome of organisms to achieve targeted modification of endogenous genes and targeted integration of exogenous genes. Current genome-editing tools mainly include ZFN, TALEN and CRISPR/Cas9, which have been successfully applied to all species tested including zebrafish, humans, mice, rats, monkeys, pigs, cattle, sheep, goats and others. The application of genome editing has quickly swept through the entire biomedical field, including livestock breeding. Traditional livestock breeding is associated with rate limiting issues such as long breeding cycle and limitations of genetic resources. Genome editing tools offer solutions to these problems at affordable costs. Generation of gene-edited livestock with improved traits has proven feasible and valuable. For example, the CD163 gene-edited pig is resistant to porcine reproductive and respiratory syndrome (PRRS, also referred to as "blue ear disease"), and a SP110 gene knock-in cow less susceptible to tuberculosis. Given the high efficiency and low cost of genome editing tools, particularly CRISPR/Cas9, it is foreseeable that a significant number of genome edited livestock animals will be produced in the near future; hence it is imperative to comprehensively evaluate the pros and cons they will bring to the livestock breeding industry. Only with these considerations in mind, we will be able to fully take the advantage of the genome editing era in livestock breeding.

Genome Editing Tools in Plants

PubMed Central

Mohanta, Tapan Kumar; Bashir, Tufail; Hashem, Abeer; Bae, Hanhong

2017-01-01

Genome editing tools have the potential to change the genomic architecture of a genome at precise locations, with desired accuracy. These tools have been efficiently used for trait discovery and for the generation of plants with high crop yields and resistance to biotic and abiotic stresses. Due to complex genomic architecture, it is challenging to edit all of the genes/genomes using a particular genome editing tool. Therefore, to overcome this challenging task, several genome editing tools have been developed to facilitate efficient genome editing. Some of the major genome editing tools used to edit plant genomes are: Homologous recombination (HR), zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), pentatricopeptide repeat proteins (PPRs), the CRISPR/Cas9 system, RNA interference (RNAi), cisgenesis, and intragenesis. In addition, site-directed sequence editing and oligonucleotide-directed mutagenesis have the potential to edit the genome at the single-nucleotide level. Recently, adenine base editors (ABEs) have been developed to mutate A-T base pairs to G-C base pairs. ABEs use deoxyadeninedeaminase (TadA) with catalytically impaired Cas9 nickase to mutate A-T base pairs to G-C base pairs. PMID:29257124

Understanding Editing Behaviors in Multilingual Wikipedia.

PubMed

Kim, Suin; Park, Sungjoon; Hale, Scott A; Kim, Sooyoung; Byun, Jeongmin; Oh, Alice H

2016-01-01

Multilingualism is common offline, but we have a more limited understanding of the ways multilingualism is displayed online and the roles that multilinguals play in the spread of content between speakers of different languages. We take a computational approach to studying multilingualism using one of the largest user-generated content platforms, Wikipedia. We study multilingualism by collecting and analyzing a large dataset of the content written by multilingual editors of the English, German, and Spanish editions of Wikipedia. This dataset contains over two million paragraphs edited by over 15,000 multilingual users from July 8 to August 9, 2013. We analyze these multilingual editors in terms of their engagement, interests, and language proficiency in their primary and non-primary (secondary) languages and find that the English edition of Wikipedia displays different dynamics from the Spanish and German editions. Users primarily editing the Spanish and German editions make more complex edits than users who edit these editions as a second language. In contrast, users editing the English edition as a second language make edits that are just as complex as the edits by users who primarily edit the English edition. In this way, English serves a special role bringing together content written by multilinguals from many language editions. Nonetheless, language remains a formidable hurdle to the spread of content: we find evidence for a complexity barrier whereby editors are less likely to edit complex content in a second language. In addition, we find that multilinguals are less engaged and show lower levels of language proficiency in their second languages. We also examine the topical interests of multilingual editors and find that there is no significant difference between primary and non-primary editors in each language.

Understanding Editing Behaviors in Multilingual Wikipedia

PubMed Central

Hale, Scott A.; Kim, Sooyoung; Byun, Jeongmin; Oh, Alice H.

2016-01-01

Multilingualism is common offline, but we have a more limited understanding of the ways multilingualism is displayed online and the roles that multilinguals play in the spread of content between speakers of different languages. We take a computational approach to studying multilingualism using one of the largest user-generated content platforms, Wikipedia. We study multilingualism by collecting and analyzing a large dataset of the content written by multilingual editors of the English, German, and Spanish editions of Wikipedia. This dataset contains over two million paragraphs edited by over 15,000 multilingual users from July 8 to August 9, 2013. We analyze these multilingual editors in terms of their engagement, interests, and language proficiency in their primary and non-primary (secondary) languages and find that the English edition of Wikipedia displays different dynamics from the Spanish and German editions. Users primarily editing the Spanish and German editions make more complex edits than users who edit these editions as a second language. In contrast, users editing the English edition as a second language make edits that are just as complex as the edits by users who primarily edit the English edition. In this way, English serves a special role bringing together content written by multilinguals from many language editions. Nonetheless, language remains a formidable hurdle to the spread of content: we find evidence for a complexity barrier whereby editors are less likely to edit complex content in a second language. In addition, we find that multilinguals are less engaged and show lower levels of language proficiency in their second languages. We also examine the topical interests of multilingual editors and find that there is no significant difference between primary and non-primary editors in each language. PMID:27171158

Efficient genome editing of differentiated renal epithelial cells.

PubMed

Hofherr, Alexis; Busch, Tilman; Huber, Nora; Nold, Andreas; Bohn, Albert; Viau, Amandine; Bienaimé, Frank; Kuehn, E Wolfgang; Arnold, Sebastian J; Köttgen, Michael

2017-02-01

Recent advances in genome editing technologies have enabled the rapid and precise manipulation of genomes, including the targeted introduction, alteration, and removal of genomic sequences. However, respective methods have been described mainly in non-differentiated or haploid cell types. Genome editing of well-differentiated renal epithelial cells has been hampered by a range of technological issues, including optimal design, efficient expression of multiple genome editing constructs, attainable mutation rates, and best screening strategies. Here, we present an easily implementable workflow for the rapid generation of targeted heterozygous and homozygous genomic sequence alterations in renal cells using transcription activator-like effector nucleases (TALENs) and the clustered regularly interspaced short palindromic repeat (CRISPR) system. We demonstrate the versatility of established protocols by generating novel cellular models for studying autosomal dominant polycystic kidney disease (ADPKD). Furthermore, we show that cell culture-validated genetic modifications can be readily applied to mouse embryonic stem cells (mESCs) for the generation of corresponding mouse models. The described procedure for efficient genome editing can be applied to any cell type to study physiological and pathophysiological functions in the context of precisely engineered genotypes.

Obama Proposes Teacher Results in Federal Law

ERIC Educational Resources Information Center

Sawchuk, Stephen

2010-01-01

In its fiscal 2011 budget request, the Obama administration has laid out its intention of carrying forward key teacher-effectiveness policies within the economic-stimulus law into the next edition of the Elementary and Secondary Education Act. In doing so, the budget proposal would invest heavily in competitive grants for new ways of recruiting,…

School Law for Kentucky Teachers and Administrators. Third Edition.

ERIC Educational Resources Information Center

Faber, Charles F.; And Others

Intended for use in school law courses of a primarily informative nature with some attention given to attitudinal concerns, this book was designed for teachers and educational administrators. The contents are divided into 13 units that contain information regarding education and the American legal system, certification and employment, religion and…

Classical Civilization (Greece-Hellenistic-Rome). Teacher's Manual. 1968 Edition.

ERIC Educational Resources Information Center

Leppert, Ella C.; Smith, Rozella B.

This secondary teachers guide builds upon a previous sequential course described in SO 003 173, and consists of three sections on the classical civilizations--Greek, Hellenistic, and Rome. Major emphasis is upon students gaining an understanding of cultural development and transmission. Using an analytic method, students learn to examine primary…

Financing Education in a Climate of Change. Eighth Edition.

ERIC Educational Resources Information Center

Brimley, Vern, Jr.; Garfield, Rulon R.

Since the publication of the seventh edition of this textbook in 1999, there have been many new developments in the education finance arena. Those changes are discussed in this eighth edition. Additional new material includes Internet resources, new exercises for further "laboratory" work, updated figures and tables, and fresh information on court…

Chemistry and the Periodic Table: Teacher's Guide Levels A, B, and C. Preliminary Limited Edition.

ERIC Educational Resources Information Center

Cambridge Physics Outlet, Woburn, MA. Education Programs Dept.

This is a two-part curriculum package for the teaching of chemistry and the periodic table. The first part, the Teacher's Guide, contains information necessary for using the equipment in a typical classroom including learning goals, vocabulary, math skills, and sample data for each activity. The second part of the package consists of photocopy…

Linea abierta -- Comunicacion en Espanol. Edicion del maestro (Open Line -- Communication in Spanish. Teacher's Edition).

ERIC Educational Resources Information Center

Dissemination and Assessment Center for Bilingual Education, Austin, TX.

This teacher's guide corresponds to the text that is the first of a series of four units concerning language skills for Spanish speakers of limited English-speaking ability in grades 6-9. The text includes a variety of learning experiences designed to develop competence in the student's cognitive and affective skills derived from the following…

The ethics of creating genetically modified children using genome editing.

PubMed

Ishii, Tetsuya

2017-12-01

To review the recent ethical, legal, and social issues surrounding human reproduction involving germline genome editing. Genome editing techniques, such as CRISPR/Cas9, have facilitated genetic modification in human embryos. The most likely purpose of germline genome editing is the prevention of serious genetic disease in offspring. However, complex issues still remain, including irremediable risks to fetuses and future generations, the role of women, the availability of alternatives, long-term follow-up, health insurance coverage, misuse for human enhancement, and the potential effects on adoption. Further discussions, a broad consensus, and appropriate regulations are required before human germline genome editing is introduced into the global society. Before germline genome editing is used for disease prevention, a broad consensus must be formed by carefully discussing its ethical, legal, and social issues.

Going to the Market. Teacher Edition. Fashion Buying Series.

ERIC Educational Resources Information Center

Collins, Cindy

This teacher's guide presents material for a unit on attending the retail fashion market. Content focuses on previewing merchandise for purchase, factors involved in a major market trip, common terms used when ordering merchandise, and pricing strategies. The guide contains 4 objectives, 6 group learning activities keyed to the objectives, 12…

Introduction to Fashion Buying. Teacher Edition. Fashion Buying Series.

ERIC Educational Resources Information Center

Collins, Cindy

This teacher's guide presents material for a unit on introduction to fashion buying. Content focuses on information sources, retail store types, the responsibilities of a buyer, and the qualifications of a buyer. The guide contains 4 objectives, 4 group learning activities keyed to the objectives, 17 transparency masters with dialogue for each,…

Non-viral delivery of genome-editing nucleases for gene therapy.

PubMed

Wang, M; Glass, Z A; Xu, Q

2017-03-01

Manipulating the genetic makeup of mammalian cells using programmable nuclease-based genome-editing technology has recently evolved into a powerful avenue that holds great potential for treating genetic disorders. There are four types of genome-editing nucleases, including meganucleases, zinc finger nucleases, transcription activator-like effector nucleases and clustered, regularly interspaced, short palindromic repeat-associated nucleases such as Cas9. These nucleases have been harnessed to introduce precise and specific changes of the genome sequence at virtually any genome locus of interest. The therapeutic relevance of these genome-editing technologies, however, is challenged by the safe and efficient delivery of nuclease into targeted cells. Herein, we summarize recent advances that have been made on non-viral delivery of genome-editing nucleases. In particular, we focus on non-viral delivery of Cas9/sgRNA ribonucleoproteins for genome editing. In addition, the future direction for developing non-viral delivery of programmable nucleases for genome editing is discussed.

Quantifying Genome Editing Outcomes at Endogenous Loci using SMRT Sequencing

PubMed Central

Clark, Joseph; Punjya, Niraj; Sebastiano, Vittorio; Bao, Gang; Porteus, Matthew H

2014-01-01

SUMMARY Targeted genome editing with engineered nucleases has transformed the ability to introduce precise sequence modifications at almost any site within the genome. A major obstacle to probing the efficiency and consequences of genome editing is that no existing method enables the frequency of different editing events to be simultaneously measured across a cell population at any endogenous genomic locus. We have developed a novel method for quantifying individual genome editing outcomes at any site of interest using single molecule real time (SMRT) DNA sequencing. We show that this approach can be applied at various loci, using multiple engineered nuclease platforms including TALENs, RNA guided endonucleases (CRISPR/Cas9), and ZFNs, and in different cell lines to identify conditions and strategies in which the desired engineering outcome has occurred. This approach facilitates the evaluation of new gene editing technologies and permits sensitive quantification of editing outcomes in almost every experimental system used. PMID:24685129

Water quality management library. 2. edition

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eckenfelder, W.W.; Malina, J.F.; Patterson, J.W.

1998-12-31

A series of ten books offered in conjunction with Water Quality International, the Biennial Conference and Exposition of the International Association on Water Pollution Research and Control (IAWPRC). Volume 1, Activated Sludge Process, Design and Control, 2nd edition, 1998: Volume 2, Upgrading Wastewater Treatment Plants, 2nd edition, 1998: Volume 3, Toxicity Reduction, 2nd edition, 1998: Volume 4, Municipal Sewage Sludge Management, 2nd edition, 1998: Volume 5, Design and Retrofit of Wastewater Treatment Plants for Biological Nutrient Removal, 1st edition, 1992: Volume 6, Dynamics and Control of the Activated Sludge Process, 2nd edition, 1998: Volume 7: Design of Anaerobic Processes formore » the Treatment of Industrial and Municipal Wastes, 1st edition, 1992: Volume 8, Groundwater Remediation, 1st edition, 1992: Volume 9, Nonpoint Pollution and Urban Stormwater Management, 1st edition, 1995: Volume 10, Wastewater Reclamation and Reuse, 1st edition, 1998.« less

Video Editing System

NASA Technical Reports Server (NTRS)

Schlecht, Leslie E.; Kutler, Paul (Technical Monitor)

1998-01-01

This is a proposal for a general use system based, on the SGI IRIS workstation platform, for recording computer animation to videotape. In addition, this system would provide features for simple editing and enhancement. Described here are a list of requirements for the system, and a proposed configuration including the SGI VideoLab Integrator, VideoMedia VLAN animation controller and the Pioneer rewritable laserdisc recorder.

Becoming a Japanese Language Learner, User, and Teacher: Revelations From Life History Research

ERIC Educational Resources Information Center

Armour, William S.

2004-01-01

This article discusses how Sarah Lamond, a Japanese language teacher in Sydney, Australia has juggled three of her identities: second language (L2) learner, L2 user, and L2 teacher. Data come from four interviews used to create an edited life history. These data are used to draw attention to the relationship between L2 learner and language user.…

REDIdb: the RNA editing database.

PubMed

Picardi, Ernesto; Regina, Teresa Maria Rosaria; Brennicke, Axel; Quagliariello, Carla

2007-01-01

The RNA Editing Database (REDIdb) is an interactive, web-based database created and designed with the aim to allocate RNA editing events such as substitutions, insertions and deletions occurring in a wide range of organisms. The database contains both fully and partially sequenced DNA molecules for which editing information is available either by experimental inspection (in vitro) or by computational detection (in silico). Each record of REDIdb is organized in a specific flat-file containing a description of the main characteristics of the entry, a feature table with the editing events and related details and a sequence zone with both the genomic sequence and the corresponding edited transcript. REDIdb is a relational database in which the browsing and identification of editing sites has been simplified by means of two facilities to either graphically display genomic or cDNA sequences or to show the corresponding alignment. In both cases, all editing sites are highlighted in colour and their relative positions are detailed by mousing over. New editing positions can be directly submitted to REDIdb after a user-specific registration to obtain authorized secure access. This first version of REDIdb database stores 9964 editing events and can be freely queried at http://biologia.unical.it/py_script/search.html.

Law, Finance, and the Teacher in Illinois. A Handbook for Teachers, Administrators, and School Board Members. Third Edition.

ERIC Educational Resources Information Center

Garber, Lee O.; And Others

This handbook explains the legal principles underlying the Illinois public education system, thereby providing teachers, administrators, and school board members with an understanding of the nature of the public school as a social and governmental institution. It also considers the legal status of Illinois teachers by defining their rights,…

The Structure of the Atom: Teacher's Guide Levels A, B, and C. Preliminary Limited Edition.

ERIC Educational Resources Information Center

Cambridge Physics Outlet, Woburn, MA. Education Programs Dept.

This is a two-part curriculum package for teaching the structure of atoms. The first part--the Teacher's Guide--contains information necessary for using the equipment in a typical classroom including learning goals, vocabulary, math skills, and sample data for each activity. The second part of the package consists of photocopy masters for a set of…

Preparing for the Market. Teacher Edition. Fashion Buying Series.

ERIC Educational Resources Information Center

Collins, Cindy

This teacher's guide presents material for a unit on preparing for the retail fashion market. Content focuses on merchandise plans, computing open-to-buy, computing turnover, the components of a model stock plan, and criteria used when selecting a supplier. The guide contains 5 objectives, 6 group learning activities keyed to the objectives, 21…

European Code against Cancer 4th Edition: Medical exposures, including hormone therapy, and cancer.

PubMed

Friis, Søren; Kesminiene, Ausrele; Espina, Carolina; Auvinen, Anssi; Straif, Kurt; Schüz, Joachim

2015-12-01

The 4th edition of the European Code against Cancer recommends limiting - or avoiding when possible - the use of hormone replacement therapy (HRT) because of the increased risk of cancer, nevertheless acknowledging that prescription of HRT may be indicated under certain medical conditions. Current evidence shows that HRT, generally prescribed as menopausal hormone therapy, is associated with an increased risk of cancers of the breast, endometrium, and ovary, with the risk pattern depending on factors such as the type of therapy (oestrogen-only or combined oestrogen-progestogen), duration of treatment, and initiation according to the time of menopause. Carcinogenicity has also been established for anti-neoplastic agents used in cancer therapy, immunosuppressants, oestrogen-progestogen contraceptives, and tamoxifen. Medical use of ionising radiation, an established carcinogen, can provide major health benefits; however, prudent practices need to be in place, with procedures and techniques providing the needed diagnostic information or therapeutic gain with the lowest possible radiation exposure. For pharmaceutical drugs and medical radiation exposure with convincing evidence on their carcinogenicity, health benefits have to be balanced against the risks; potential increases in long-term cancer risk should be considered in the context of the often substantial and immediate health benefits from diagnosis and/or treatment. Thus, apart from HRT, no general recommendations on reducing cancer risk were given for carcinogenic drugs and medical radiation in the 4th edition of European Code against Cancer. It is crucial that the application of these measures relies on medical expertise and thorough benefit-risk evaluation. This also pertains to cancer-preventive drugs, and self-medication with aspirin or other potential chemopreventive drugs is strongly discouraged because of the possibility of serious, potentially lethal, adverse events. Copyright © 2015 International

Me and My Environment, Unit IV: Transfer and Cycling of Materials in My Environment, Experimental Edition 1973-74.

ERIC Educational Resources Information Center

Biological Sciences Curriculum Study, Boulder, CO.

The experimental 1973-74 edition of Unit IV consists of 28 life science curriculum activities for 13- to 16-year-old educable mentally handicapped children. The role of the teacher in continuing field trials is noted and environmental themes and elements, inquiry skills, problem solving skills, and applicational behaviors and attitudes are…

Particle Physics, 2nd Edition

NASA Astrophysics Data System (ADS)

Martin, B. R.; Shaw, G.

1998-01-01

Particle Physics, Second Edition is a concise and lucid account of the fundamental constituents of matter. The standard model of particle physics is developed carefully and systematically, without heavy mathematical formalism, to make this stimulating subject accessible to undergraduate students. Throughout, the emphasis is on the interpretation of experimental data in terms of the basic properties of quarks and leptons, and extensive use is made of symmetry principles and Feynman diagrams, which are introduced early in the book. The Second Edition brings the book fully up to date, including the discovery of the top quark and the search for the Higgs boson. A final short chapter is devoted to the continuing search for new physics beyond the standard model. Particle Physics, Second Edition features: * A carefully structured and written text to help students understand this exciting and demanding subject. * Many worked examples and problems to aid student learning. Hints for solving the problems are given in an Appendix. * Optional "starred" sections and appendices, containing more specialised and advanced material for the more ambitious reader.

CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_Terra-FM1_Edition1-CV)

NASA Technical Reports Server (NTRS)

Wielicki, Bruce A. (Principal Investigator)

Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2006-11-02] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

Foundations of Psychological Testing: A Practical Approach. Second Edition

ERIC Educational Resources Information Center

McIntire, Sandra A.; Miller, Leslie A.

2006-01-01

The second edition of "Foundations of Psychological Testing: A Practical Approach" is a text for undergraduate students new to the field of psychological testing. Using a conversational format, the authors aim to prepare students to be informed consumers as test users or test takers. Features new to the second edition include: (1) New Content; (2)…

Experiences of Enterprising Teachers: 42 Great Ideas for Teaching Economics, Grades K-12. Volume 34.

ERIC Educational Resources Information Center

Nuechterlein, Dot, Ed.; Dick, James

This booklet is the 34th edition of "Experiences of Enterprising Teachers" and describes the 42 projects selected to receive National Awards for Teaching Economics. Seventy-four teachers from the primary through the senior high school level developed the curricula to help their students understand how the world works, today, tomorrow, and the day…

Cooperation in the Classroom: Students and Teachers Together. Analysis and Action Series. Second Edition.

ERIC Educational Resources Information Center

Cangelosi, James S.

The central question addressed by this book is, "How can middle and secondary school teachers overcome seemingly impossible circumstances in the classroom and elicit students' attention, effort, and cooperation?" The first five chapters focus on teachers' responsibility for student's classroom behavior, and ways for teachers to manage…

Editing the human genome: where ART and science intersect.

PubMed

Hershlag, Avner; Bristow, Sara L

2018-06-07

The rapid development of gene-editing technologies has led to an exponential rise in both basic and translational research initiatives studying molecular processes and investigating possible clinical applications. Early experiments using genome editing to study human embryo development have contradicted findings in studies on model organisms. Additionally, a series of four experiments over the past 2 years set out to investigate the possibilities of introducing genetic modifications to human embryos, each with varying levels of success. Here, we discuss the key findings of these studies, including the efficiency, the safety, the potential untoward effects, major flaws of the studies, and emerging alternative genome editing methods that may allow overcoming the hurdles encountered so far. Given these results, we also raise several questions about the clinical utilization of germline gene editing: For which indications is gene editing appropriate? How do gene-editing technologies compare with genetic testing methods currently used for screening embryos? What are the ethical considerations we should be concerned about? While further research is underway, and our understanding of how to implement this technology continues to evolve, it is critical to contemplate if and how it should be translated from the bench to clinical practice.

The Community College Story. Third Edition

ERIC Educational Resources Information Center

Vaughan, George B.

2006-01-01

This concise history of community colleges touches on major themes, including open access and equity, comprehensiveness, community-based philosophy, commitment to teaching, and lifelong learning. The third edition includes revised text as well as updated statistical information, time line, reading list, and Internet resources. In the more than a…

CRISPR-Mediated Epigenome Editing

PubMed Central

Enríquez, Paul

2016-01-01

Mounting evidence has called into question our understanding of the role that the central dogma of molecular biology plays in human pathology. The conventional view that elucidating the mechanisms for translating genes into proteins can account for a panoply of diseases has proven incomplete. Landmark studies point to epigenetics as a missing piece of the puzzle. However, technological limitations have hindered the study of specific roles for histone post-translational modifications, DNA modifications, and non-coding RNAs in regulation of the epigenome and chromatin structure. This feature highlights CRISPR systems, including CRISPR-Cas9, as novel tools for targeted epigenome editing. It summarizes recent developments in the field, including integration of optogenetic and functional genomic approaches to explore new therapeutic opportunities, and underscores the importance of mitigating current limitations in the field. This comprehensive, analytical assessment identifies current research gaps, forecasts future research opportunities, and argues that as epigenome editing technologies mature, overcoming critical challenges in delivery, specificity, and fidelity should clear the path to bring these technologies into the clinic. PMID:28018139

CRISPR-Mediated Epigenome Editing.

PubMed

Enríquez, Paul

2016-12-01

Mounting evidence has called into question our understanding of the role that the central dogma of molecular biology plays in human pathology. The conventional view that elucidating the mechanisms for translating genes into proteins can account for a panoply of diseases has proven incomplete. Landmark studies point to epigenetics as a missing piece of the puzzle. However, technological limitations have hindered the study of specific roles for histone post-translational modifications, DNA modifications, and non-coding RNAs in regulation of the epigenome and chromatin structure. This feature highlights CRISPR systems, including CRISPR-Cas9, as novel tools for targeted epigenome editing. It summarizes recent developments in the field, including integration of optogenetic and functional genomic approaches to explore new therapeutic opportunities, and underscores the importance of mitigating current limitations in the field. This comprehensive, analytical assessment identifies current research gaps, forecasts future research opportunities, and argues that as epigenome editing technologies mature, overcoming critical challenges in delivery, specificity, and fidelity should clear the path to bring these technologies into the clinic.

BE-PLUS: a new base editing tool with broadened editing window and enhanced fidelity.

PubMed

Jiang, Wen; Feng, Songjie; Huang, Shisheng; Yu, Wenxia; Li, Guanglei; Yang, Guang; Liu, Yajing; Zhang, Yu; Zhang, Lei; Hou, Yu; Chen, Jia; Chen, Jieping; Huang, Xingxu

2018-06-06

Base editor (BE), containing a cytidine deaminase and catalytically defective Cas9, has been widely used to perform base editing. However, the narrow editing window of BE limits its utility. Here, we developed a new editing technology named as base editor for programming larger C to U (T) scope (BE-PLUS) by fusing 10 copies of GCN4 peptide to nCas9(D10A) for recruiting scFv-APOBEC-UGI-GB1 to the target sites. The new system achieves base editing with a broadened window, resulting in an increased genome-targeting scope. Interestingly, the new system yielded much fewer unwanted indels and non-C-to-T conversions. We also demonstrated its potential use in gene disruption across the whole genome through induction of stop codons (iSTOP). Taken together, the BE-PLUS system offers a new editing tool with increased editing window and enhanced fidelity.

[CRISPR/CAS9, the King of Genome Editing Tools].

PubMed

Bannikov, A V; Lavrov, A V

2017-01-01

The discovery of CRISPR/Cas9 brought a hope for having an efficient, reliable, and readily available tool for genome editing. CRISPR/Cas9 is certainly easy to use, while its efficiency and reliability remain the focus of studies. The review describes the general principles of the organization and function of Cas nucleases and a number of important issues to be considered while planning genome editing experiments with CRISPR/Cas9. The issues include evaluation of the efficiency and specificity for Cas9, sgRNA selection, Cas9 variants designed artificially, and use of homologous recombination and nonhomologous end joining in DNA editing.

Human coding RNA editing is generally nonadaptive

PubMed Central

Xu, Guixia; Zhang, Jianzhi

2014-01-01

Impairment of RNA editing at a handful of coding sites causes severe disorders, prompting the view that coding RNA editing is highly advantageous. Recent genomic studies have expanded the list of human coding RNA editing sites by more than 100 times, raising the question of how common advantageous RNA editing is. Analyzing 1,783 human coding A-to-G editing sites, we show that both the frequency and level of RNA editing decrease as the importance of a site or gene increases; that during evolution, edited As are more likely than unedited As to be replaced with Gs but not with Ts or Cs; and that among nonsynonymously edited As, those that are evolutionarily least conserved exhibit the highest editing levels. These and other observations reveal the overall nonadaptive nature of coding RNA editing, despite the presence of a few sites in which editing is clearly beneficial. We propose that most observed coding RNA editing results from tolerable promiscuous targeting by RNA editing enzymes, the original physiological functions of which remain elusive. PMID:24567376

A single alteration 20 nt 5′ to an editing target inhibits chloroplast RNA editing in vivo

PubMed Central

Reed, Martha L.; Peeters, Nemo M.; Hanson, Maureen R.

2001-01-01

Transcripts of typical dicot plant plastid genes undergo C→U RNA editing at approximately 30 locations, but there is no consensus sequence surrounding the C targets of editing. The cis-acting elements required for editing of the C located at tobacco rpoB editing site II were investigated by introducing translatable chimeric minigenes containing sequence –20 to +6 surrounding the C target of editing. When the –20 to +6 sequence specified by the homologous region present in the black pine chloroplast genome was incorporated, virtually no editing of the transcripts occurred in transgenic tobacco plastids. Nucleotides that differ between the black pine and tobacco sequence were tested for their role in C→U editing by designing chimeric genes containing one or more of these divergent nucleotides. Surprisingly, the divergent nucleotide that had the strongest negative effect on editing of the minigene transcript was located –20 nt 5′ to the C target of editing. Expression of transgene transcripts carrying the 27 nt sequence did not affect the editing extent of the endogenous rpoB transcripts, even though the chimeric transcripts were much more abundant than those of the endogenous gene. In plants carrying a 93 nt rpoB editing site sequence, transgene transcripts accumulated to a level three times greater than transgene transcripts in the plants carrying the 27 nt rpoB editing sites and resulted in editing of the endogenous transcripts from 100 to 50%. Both a lower affinity of the 27 nt site for a trans-acting factor and lower abundance of the transcript could explain why expression of minigene transcripts containing the 27 nt sequence did not affect endogenous editing. PMID:11266552

Description of Workshop Series for Precollege Teachers on Women and Gender, Including Topics Covered, Readings Used, and Sample Handouts.

ERIC Educational Resources Information Center

Chapman, Anne

A 2-year curriculum transformation project for 12 humanities teachers from seven independent schools sought to help pre-college teachers integrate new information and insights based on women's studies and gender scholarship into their teaching. Topics covered during the workshops included the history of concern with women and gender; engenderment…

Pre-EDIT: protocol for a randomised feasibility trial of elastance-directed intrapleural catheter or talc pleurodesis (EDIT) in malignant pleural effusion

PubMed Central

Martin, Geoffrey A; Tsim, Selina; Kidd, Andrew C; Foster, John E; McLoone, Philip; Chalmers, Anthony

2018-01-01

Introduction Non-expansile lung (NEL) is a common cause of talc pleurodesis (TP) failure in malignant pleural effusion (MPE), but is often occult prior to drainage. Reliable detection of NEL would allow patients to be allocated between intrapleural catheter (IPC) and TP. High pleural elastance (PEL) has been associated with NEL in observational studies. Pre-EDIT is a randomised feasibility trial of elastance-directed IPC or TP (EDIT) management using a novel, purpose-built digital pleural manometer (Rocket Medical, UK). Methods and analysis Consecutive patients with MPE without prior evidence of NEL or preference for IPC will be randomised 1:1 between EDIT management and standard care (an attempt at TP). The primary objective is to determine whether sufficient numbers of patients (defined as 30 within 12 months (or 15 over 6 months)) can be recruited and randomised to justify a subsequent phase III trial testing the efficacy of EDIT management. Secondary objectives include safety, technical feasibility and validation of study design elements, including the definition of PEL using 4D pleural MRI before and after fluid aspiration. EDIT involves PEL assessment during a large volume pleural fluid aspiration, followed by an attempt at TP or placement of an IPC within 24 hours. Patients will be allocated to IPC if the rolling average PEL sustained over at least 250 mL fluid aspirated (PEL250) is ≥ 14.5 cm H2O/L. Ethics and dissemination Pre-EDIT was approved by the West of Scotland Regional Ethics Committee on 8 March 2017 (Ref: 17/WS/0042). Results will be presented at scientific meetings and published in peer-reviewed journals. Trial registration number NCT03319186; Pre-results. PMID:29862030

The Kamusi Project Edit Engine: A Tool for Collaborative Lexicography.

ERIC Educational Resources Information Center

Benjamin, Martin; Biersteker, Ann

2001-01-01

Discusses the design and implementation of the Kamusi Project Edit Engine, a Web-based software system uniquely suited to the needs of Swahili collaborative lexicography. Describes the edit engine, including organization of the lexicon and the mechanics by which participants use the system, discusses philosophical issues confronted in the design,…

Introduction to Energy - 2nd Edition

NASA Astrophysics Data System (ADS)

Cassedy, Edward S.; Grossman, Peter Z.

1998-12-01

Energy issues such as pollution, resource depletion, global warming, nuclear power and waste are problems that demand timely solutions. This book provides a critical examination of the resources, market forces, and social impacts of modern energy production. The book addresses the dilemmas that have arisen due to society's crucial dependence on energy, particularly fossil fuels, and explores the available alternative energy producing technologies. The second edition has increased emphasis on those issues at the forefront of the current energy debate: energy sustainability, climate change, and the radical restructuring of the power industry due to de-regulation. Assuming no prior technical expertise and avoiding complex mathematical formulation, it is directed at a broad readership. The second edition will follow the first in proving especially useful as a textbook for undergraduate programs in Science, Technology and Society (STS), and as a supplementary text in a variety of courses which touch upon energy studies, including environmental and technology policy, environmental, mineral and business law, energy and resource economics. Fully updated second edition of successful first edition that was adopted on Science, Technology and Society courses Provides a critical examination of all aspects of modern energy production for non-technical readers For a broad readership from a variety of backgrounds

Teacher Attitudes on Including Students with Behavior Intervention Plans in a High-School Inclusive Classroom

ERIC Educational Resources Information Center

Tucker, Thurman D.

2017-01-01

This research examined attitudes to determine factors influencing teachers' attitudes toward including students with behavior intervention plans in inclusive high-school classrooms. For Research Question 1 one-way ANOVAs analyzed quantitative data with no significant differences found and qualitative data discovered common patterns that BIPs are…

SCDC Spanish Curricula Units. Social Science Strand, Unit 2, Grade One, Teacher's Guide--Multi-Ethnic Edition.

ERIC Educational Resources Information Center

Spanish Curricula Development Center, Miami Beach, FL.

Building on a unit designed to help first graders adjust to the classroom environment, this teacher's guide for the second bilingual social science instructional unit includes material which expands the conceptual field of the child to the family. The Spanish-English guide presents instructional and assessment activities for kits five through…

The Chloroplast Genome of Pellia endiviifolia: Gene Content, RNA-Editing Pattern, and the Origin of Chloroplast Editing

PubMed Central

Grosche, Christopher; Funk, Helena T.; Maier, Uwe G.; Zauner, Stefan

2012-01-01

RNA editing is a post-transcriptional process that can act upon transcripts from mitochondrial, nuclear, and chloroplast genomes. In chloroplasts, single-nucleotide conversions in mRNAs via RNA editing occur at different frequencies across the plant kingdom. These range from several hundred edited sites in some mosses and ferns to lower frequencies in seed plants and the complete lack of RNA editing in the liverwort Marchantia polymorpha. Here, we report the sequence and edited sites of the chloroplast genome from the liverwort Pellia endiviifolia. The type and frequency of chloroplast RNA editing display a pattern highly similar to that in seed plants. Analyses of the C to U conversions and the genomic context in which the editing sites are embedded provide evidence in favor of the hypothesis that chloroplast RNA editing evolved to compensate mutations in the first land plants. PMID:23221608

Blueprint for Change in Ohio: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Utah: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Mississippi: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Florida: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Maryland: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Louisiana: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Massachusetts: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Illinois: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Nevada: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Iowa: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Washington: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Alabama: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Michigan: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Hawaii: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Minnesota: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Pennsylvania: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Texas: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Idaho: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Arizona: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Wisconsin: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Montana: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Arkansas: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Kansas: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Vermont: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Oregon: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Alaska: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in Wyoming: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Digital Video Editing

ERIC Educational Resources Information Center

McConnell, Terry

2004-01-01

Monica Adams, head librarian at Robinson Secondary in Fairfax country, Virginia, states that librarians should have the technical knowledge to support projects related to digital video editing. The process of digital video editing and the cables, storage issues and the computer system with software is described.

ETC 408/508: Technical Editing

ERIC Educational Resources Information Center

Charlton, Michael

2013-01-01

The course will focus on the role of the editor in organizational settings, including creating successful writer/editor collaboration. Students will gain practice in editing documents for grammar, syntax, organization, style, emphasis, document design, graphics, and user-centered design. The course will provide an introduction to technology for…

Teaching Reading Sourcebook, Second Edition

ERIC Educational Resources Information Center

Honig, Bill; Diamond, Linda; Gutlohn, Linda

2008-01-01

The "Teaching Reading Sourcebook, Second Edition" is a comprehensive reference about reading instruction. Organized according to the elements of explicit instruction (what? why? when? and how?), the "Sourcebook" includes both a research-informed knowledge base and practical sample lesson models. It teaches the key elements of an effective reading…

Teaching Secondary Mathematics. Second Edition.

ERIC Educational Resources Information Center

Brumbaugh, Douglas K.; Rock, David

This book for future mathematics teachers emphasizes technology as a teaching tool; development of teachers who are self-motivated, lifelong learners; and pedagogical features that engage and motivate students. It includes examples and activities to enhance learning. Part 1, "General Fundamentals," includes (1) "Introduction"; (2) "Learning,…

Engineering Delivery Vehicles for Genome Editing.

PubMed

Nelson, Christopher E; Gersbach, Charles A

2016-06-07

The field of genome engineering has created new possibilities for gene therapy, including improved animal models of disease, engineered cell therapies, and in vivo gene repair. The most significant challenge for the clinical translation of genome engineering is the development of safe and effective delivery vehicles. A large body of work has applied genome engineering to genetic modification in vitro, and clinical trials have begun using cells modified by genome editing. Now, promising preclinical work is beginning to apply these tools in vivo. This article summarizes the development of genome engineering platforms, including meganucleases, zinc finger nucleases, TALENs, and CRISPR/Cas9, and their flexibility for precise genetic modifications. The prospects for the development of safe and effective viral and nonviral delivery vehicles for genome editing are reviewed, and promising advances in particular therapeutic applications are discussed.

Condition-specific RNA editing in the coral symbiont Symbiodinium microadriaticum

PubMed Central

Li, Yong

2017-01-01

RNA editing is a rare post-transcriptional event that provides cells with an additional level of gene expression regulation. It has been implicated in various processes including adaptation, viral defence and RNA interference; however, its potential role as a mechanism in acclimatization has just recently been recognised. Here, we show that RNA editing occurs in 1.6% of all nuclear-encoded genes of Symbiodinium microadriaticum, a dinoflagellate symbiont of reef-building corals. All base-substitution edit types were present, and statistically significant motifs were associated with three edit types. Strikingly, a subset of genes exhibited condition-specific editing patterns in response to different stressors that resulted in significant increases of non-synonymous changes. We posit that this previously unrecognised mechanism extends this organism’s capability to respond to stress beyond what is encoded by the genome. This in turn may provide further acclimatization capacity to these organisms, and by extension, their coral hosts. PMID:28245292

[Advances in CRISPR-Cas-mediated genome editing system in plants].

PubMed

Wang, Chun; Wang, Kejian

2017-10-25

Targeted genome editing technology is an important tool to study the function of genes and to modify organisms at the genetic level. Recently, CRISPR-Cas (clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins) system has emerged as an efficient tool for specific genome editing in animals and plants. CRISPR-Cas system uses CRISPR-associated endonuclease and a guide RNA to generate double-strand breaks at the target DNA site, subsequently leading to genetic modifications. CRISPR-Cas system has received widespread attention for manipulating the genomes with simple, easy and high specificity. This review summarizes recent advances of diverse applications of the CRISPR-Cas toolkit in plant research and crop breeding, including expanding the range of genome editing, precise editing of a target base, and efficient DNA-free genome editing technology. This review also discusses the potential challenges and application prospect in the future, and provides a useful reference for researchers who are interested in this field.

Teacher and Parent Ratings of Children with Depressive Disorders

ERIC Educational Resources Information Center

Mattison, Richard E.; Carlson, Gabrielle A.; Cantwell, Dennis P.; Asarnow, Joan Rosenbaum

2007-01-01

The fields of child psychology and psychiatry have not yet established the clinical presentation in school of children and adolescents who have been diagnosed as having a depressive disorder. To address this issue, the authors used teacher ratings on scale oriented to the third, revised edition of the "Diagnostic and Statistical Manual of…

What Do K-12 Teachers Think about Including Student Surveys in Their Performance Ratings?

ERIC Educational Resources Information Center

Dretzke, Beverly J.; Sheldon, Timothy D.; Lim, Alicia

2015-01-01

This study investigated K-12 teachers' opinions about the use of student surveys as a component of a teacher evaluation system. Surveys were administered to teachers at the beginning of the school year and again in the spring. Analyses of teachers' responses on the fall survey indicated tentative support for the inclusion of student feedback in…

Steric antisense inhibition of AMPA receptor Q/R editing reveals tight coupling to intronic editing sites and splicing

PubMed Central

Penn, Andrew C.; Balik, Ales; Greger, Ingo H.

2013-01-01

Adenosine-to-Inosine (A-to-I) RNA editing is a post-transcriptional mechanism, evolved to diversify the transcriptome in metazoa. In addition to wide-spread editing in non-coding regions protein recoding by RNA editing allows for fine tuning of protein function. Functional consequences are only known for some editing sites and the combinatorial effect between multiple sites (functional epistasis) is currently unclear. Similarly, the interplay between RNA editing and splicing, which impacts on post-transcriptional gene regulation, has not been resolved. Here, we describe a versatile antisense approach, which will aid resolving these open questions. We have developed and characterized morpholino oligos targeting the most efficiently edited site—the AMPA receptor GluA2 Q/R site. We show that inhibition of editing closely correlates with intronic editing efficiency, which is linked to splicing efficiency. In addition to providing a versatile tool our data underscore the unique efficiency of a physiologically pivotal editing site. PMID:23172291

[Preface for genome editing special issue].

PubMed

Gu, Feng; Gao, Caixia

2017-10-25

Genome editing technology, as an innovative biotechnology, has been widely used for editing the genome from model organisms, animals, plants and microbes. CRISPR/Cas9-based genome editing technology shows its great value and potential in the dissection of functional genomics, improved breeding and genetic disease treatment. In the present special issue, the principle and application of genome editing techniques has been summarized. The advantages and disadvantages of the current genome editing technology and future prospects would also be highlighted.

Teacher Educators' and Student Teachers' Beliefs about Preparation for Working with Families Including Those from Diverse Socioeconomic and Cultural Backgrounds

ERIC Educational Resources Information Center

D'Haem, Jeanne; Griswold, Peter

2017-01-01

This mixed-methods study examined teacher preparation for developing family partnerships. The attitudes and practices of teacher educators and the attitudes and experiences of student teachers were explored in focus groups, documents, and a survey instrument. Results indicated that although partnerships were considered important by faculty and…

Key Stage 3 Mathematics Teachers: The Current Situation, Initiatives and Visions. Proceedings of a National Day Conference.

ERIC Educational Resources Information Center

Johnston-Wilder, Sue

This book contains edited versions of papers presented at a conference held at The Open University. The papers provide significant evidence of the depth of the problem of supply and retention of teachers of mathematics, and discusses the need for a structural review of the recruitment, selection, and training of teachers of mathematics. The…

Salient Features of Endonuclease Platforms for Therapeutic Genome Editing.

PubMed

Certo, Michael T; Morgan, Richard A

2016-03-01

Emerging gene-editing technologies are nearing a revolutionary phase in genetic medicine: precisely modifying or repairing causal genetic defects. This may include any number of DNA sequence manipulations, such as knocking out a deleterious gene, introducing a particular mutation, or directly repairing a defective sequence by site-specific recombination. All of these edits can currently be achieved via programmable rare-cutting endonucleases to create targeted DNA breaks that can engage and exploit endogenous DNA repair pathways to impart site-specific genetic changes. Over the past decade, several distinct technologies for introducing site-specific DNA breaks have been developed, yet the different biological origins of these gene-editing technologies bring along inherent differences in parameters that impact clinical implementation. This review aims to provide an accessible overview of the various endonuclease-based gene-editing platforms, highlighting the strengths and weakness of each with respect to therapeutic applications.

Salient Features of Endonuclease Platforms for Therapeutic Genome Editing

PubMed Central

Certo, Michael T; Morgan, Richard A

2016-01-01

Emerging gene-editing technologies are nearing a revolutionary phase in genetic medicine: precisely modifying or repairing causal genetic defects. This may include any number of DNA sequence manipulations, such as knocking out a deleterious gene, introducing a particular mutation, or directly repairing a defective sequence by site-specific recombination. All of these edits can currently be achieved via programmable rare-cutting endonucleases to create targeted DNA breaks that can engage and exploit endogenous DNA repair pathways to impart site-specific genetic changes. Over the past decade, several distinct technologies for introducing site-specific DNA breaks have been developed, yet the different biological origins of these gene-editing technologies bring along inherent differences in parameters that impact clinical implementation. This review aims to provide an accessible overview of the various endonuclease-based gene-editing platforms, highlighting the strengths and weakness of each with respect to therapeutic applications. PMID:26796671

Special-effect edit detection using VideoTrails: a comparison with existing techniques

NASA Astrophysics Data System (ADS)

Kobla, Vikrant; DeMenthon, Daniel; Doermann, David S.

1998-12-01

Video segmentation plays an integral role in many multimedia applications, such as digital libraries, content management systems, and various other video browsing, indexing, and retrieval systems. Many algorithms for segmentation of video have appeared within the past few years. Most of these algorithms perform well on cuts, but yield poor performance on gradual transitions or special effects edits. A complete video segmentation system must also achieve good performance on special effect edit detection. In this paper, we discuss the performance of our Video Trails-based algorithms, with other existing special effect edit-detection algorithms within the literature. Results from experiments testing for the ability to detect edits from TV programs, ranging from commercials to news magazine programs, including diverse special effect edits, which we have introduced.

Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes.

PubMed

Hess, Gaelen T; Tycko, Josh; Yao, David; Bassik, Michael C

2017-10-05

The past several years have seen an explosion in development of applications for the CRISPR-Cas9 system, from efficient genome editing, to high-throughput screening, to recruitment of a range of DNA and chromatin-modifying enzymes. While homology-directed repair (HDR) coupled with Cas9 nuclease cleavage has been used with great success to repair and re-write genomes, recently developed base-editing systems present a useful orthogonal strategy to engineer nucleotide substitutions. Base editing relies on recruitment of cytidine deaminases to introduce changes (rather than double-stranded breaks and donor templates) and offers potential improvements in efficiency while limiting damage and simplifying the delivery of editing machinery. At the same time, these systems enable novel mutagenesis strategies to introduce sequence diversity for engineering and discovery. Here, we review the different base-editing platforms, including their deaminase recruitment strategies and editing outcomes, and compare them to other CRISPR genome-editing technologies. Additionally, we discuss how these systems have been applied in therapeutic, engineering, and research settings. Lastly, we explore future directions of this emerging technology. Copyright © 2017 Elsevier Inc. All rights reserved.

Global Bathymetry: Machine Learning for Data Editing

NASA Astrophysics Data System (ADS)

Sandwell, D. T.; Tea, B.; Freund, Y.

2017-12-01

The accuracy of global bathymetry depends primarily on the coverage and accuracy of the sounding data and secondarily on the depth predicted from gravity. A main focus of our research is to add newly-available data to the global compilation. Most data sources have 1-12% of erroneous soundings caused by a wide array of blunders and measurement errors. Over the years we have hand-edited this data using undergraduate employees at UCSD (440 million soundings at 500 m resolution). We are developing a machine learning approach to refine the flagging of the older soundings and provide automated editing of newly-acquired soundings. The approach has three main steps: 1) Combine the sounding data with additional information that may inform the machine learning algorithm. The additional parameters include: depth predicted from gravity; distance to the nearest sounding from other cruises; seafloor age; spreading rate; sediment thickness; and vertical gravity gradient. 2) Use available edit decisions as training data sets for a boosted tree algorithm with a binary logistic objective function and L2 regularization. Initial results with poor quality single beam soundings show that the automated algorithm matches the hand-edited data 89% of the time. The results show that most of the information for detecting outliers comes from predicted depth with secondary contributions from distance to the nearest sounding and longitude. A similar analysis using very high quality multibeam data shows that the automated algorithm matches the hand-edited data 93% of the time. Again, most of the information for detecting outliers comes from predicted depth secondary contributions from distance to the nearest sounding and longitude. 3) The third step in the process is to use the machine learning parameters, derived from the training data, to edit 12 million newly acquired single beam sounding data provided by the National Geospatial-Intelligence Agency. The output of the learning algorithm will be

Graph edit distance from spectral seriation.

PubMed

Robles-Kelly, Antonio; Hancock, Edwin R

2005-03-01

This paper is concerned with computing graph edit distance. One of the criticisms that can be leveled at existing methods for computing graph edit distance is that they lack some of the formality and rigor of the computation of string edit distance. Hence, our aim is to convert graphs to string sequences so that string matching techniques can be used. To do this, we use a graph spectral seriation method to convert the adjacency matrix into a string or sequence order. We show how the serial ordering can be established using the leading eigenvector of the graph adjacency matrix. We pose the problem of graph-matching as a maximum a posteriori probability (MAP) alignment of the seriation sequences for pairs of graphs. This treatment leads to an expression in which the edit cost is the negative logarithm of the a posteriori sequence alignment probability. We compute the edit distance by finding the sequence of string edit operations which minimizes the cost of the path traversing the edit lattice. The edit costs are determined by the components of the leading eigenvectors of the adjacency matrix and by the edge densities of the graphs being matched. We demonstrate the utility of the edit distance on a number of graph clustering problems.

Calculus of Elementary Functions, Part IV. Teacher's Commentary. Preliminary Edition.

ERIC Educational Resources Information Center

Herriot, Sarah T.; And Others

This teacher's guide is designed for use with the SMSG textbook "Calculus of Elementary Functions." It contains solutions to exercises found in Chapter 9, Integration Theory and Technique; Chapter 10, Simple Differential Equations; Appendix 5, Area and Integral; Appendix 6; Appendix 7, Continuity Theory; and Appendix 8, More About…

How the Brain Learns: A Classroom Teacher's Guide. Second Edition.

ERIC Educational Resources Information Center

Sousa, David A.

This book presents information to help teachers turn research on brain function into practical classroom activities and lessons, offering: brain facts; information on how the brain processes information; tips on maximizing retention; an information processing model that reflects new terminology regarding the memory systems; new research on how the…

The Caring Teacher's Guide to Discipline: Helping Young Students Learn Self-Control, Responsibility, and Respect. Second Edition.

ERIC Educational Resources Information Center

Gootman, Marilyn E.

This book provides a comprehensive guide to teaching students to do the right thing. After "Introduction: Caring Teachers Can Make a Difference," 11 chapters include: (1) "Setting the Stage for Appropriate Behavior"; (2) "Expectations, Limits, and Rules" (unreasonable barricades and how to build moderate fences); (3)…

[Appraisal of occupational stress and strain in primary and secondary school teachers].

PubMed

Wang, Z; Lan, Y; Li, J; Wang, M

2001-09-01

This study was conducted to assess occupational stress and strain in primary and secondary school teachers. A test of occupational stress and strain was carried out by using Occupational Stress Inventory Revised Edition (OSI-R) in 1460 primary and secondary school teachers (teacher group) and 319 mental workers in non-educational area (non-teacher group as control). The results showed the level of occupational stress in role overload and physical environment in the teacher group was significantly higher than that in the non-teacher group (P < 0.05). In teacher group the level of occupational stress and strain increased with age; the occupational stress and strain in male teachers were significantly higher than those in female teachers (P < 0.01); the occupational stress and strain in secondary school teachers were significantly higher than those in primary school teachers. These results indicate: to protect and promote primary and secondary school teacher's health, particularly male teachers' health, to mitigate their work pressure and to raise the quality of education are important tasks in the area of occupational health.

Motivating and Inspiring Teachers: The Educational Leader's Guide for Building Staff Morale. Second Edition

ERIC Educational Resources Information Center

Whitaker, Todd; Whitaker, Beth; Lumpa, Dale

2009-01-01

Like the best-selling first edition, this book is filled with strategies to motivate your staff and maintain a high level of energy at your school. This guide will help all educators approach work every day in an enthusiastic, focused, and positive state of mind. This book will help you: (1) Motivate your faculty with the Friday Focus; (2)…

The World of Business. Teacher's Activity and Resource Guide.

ERIC Educational Resources Information Center

Columbus Public Schools, OH.

This activity and resource guide is intended to assist teachers in developing course content and effective teaching methods in business education. (General Business for Economic Understanding," 11th edition, is the adopted textbook for this guide.) The guide is organized into twelve major units and is designed so that each unit builds upon the…

Justice. Law in a Free Society Series. Level VI. Teacher's Guide. Second Edition.

ERIC Educational Resources Information Center

Center for Civic Education, Calabasas, CA.

This teacher's curriculum guide is designed to help high school teachers guide students to develop a better understanding of difficult issues raised by questions of justice. It is hoped that the ideas, observations, questions, and procedures students learn in the curriculum will help them to make informed decisions about how to promote justice and…

The Math We Need to Know and Do in Grades 6-9: Concepts, Skills, Standards, and Assessments. Second Edition

ERIC Educational Resources Information Center

Solomon, Pearl Gold

2007-01-01

In a new edition of her standards-based math workbook, author Pearl Gold Solomon covers essential concepts and skills as defined by the National Council of Teachers of Mathematics for learners in middle schools. Designed as a comprehensive resource for planning curriculum, instruction, and assessment, The Math We Need to Know and Do in Grades 6-9,…

Blueprint for Change in South Dakota: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in North Dakota: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in North Carolina: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in New Hampshire: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in New Mexico: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in West Virginia: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Blueprint for Change in South Carolina: State Teacher Policy Yearbook, 2010

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2010

2010-01-01

The 2009 "State Teacher Policy Yearbook" provided a comprehensive review of states' policies that impact the teaching profession. As a companion to last year's comprehensive state-by-state analysis, the 2010 edition provides each state with an individualized "Blueprint for Change," building off last year's "Yearbook"…

Canadian Counsellor. Special Edition on Employment Counselling = Conseiller Canadien. Edition Speciale sur le Counselling d'Emploi.

ERIC Educational Resources Information Center

Paquin, Andre, Ed.

1980-01-01

This special edition on employment counseling contains a series of articles demonstrating some of the employment counseling initiatives currently underway in Canada. Included are separate English and French texts of each of the following articles: "The Assessment Component of Employment Counselling: Some Suggestions," by P. J. Patsula…

Catalog of Infrared Observations, Third Edition

NASA Technical Reports Server (NTRS)

Gezari, Daniel Y.; Schmitz, Marion; Pitts, Patricia S.; Mead, Jaylee M.

1993-01-01

The Far Infrared Supplement contains a subset of the data in the full Catalog of Infrared Observations (all observations at wavelengths greater than 4.6 microns). The Catalog of Infrared Observations (CIO), NASA RP-1294, is a compilation of infrared astronomical observational data obtained from an extensive literature search of scientific journals and major astronomical catalogs and surveys. The literature search is complete for years 1965 through 1990 in this Third Edition. The Catalog contains about 210,000 observations of roughly 20,000 individual sources and supporting appendices. The expanded Third Edition contains coded IRAS 4-band data for all CIO sources detected by IRAS. The appendices include an atlas of infrared source positions (also included in this volume), two bibliographies of Catalog listings, and an atlas of infrared spectral ranges. The complete CIO database is available to qualified users in printed, microfiche, and magnetic-tape formats.

Statistical Physics Approaches to RNA Editing

NASA Astrophysics Data System (ADS)

Bundschuh, Ralf

2012-02-01

The central dogma of molecular Biology states that DNA is transcribed base by base into RNA which is in turn translated into proteins. However, some organisms edit their RNA before translation by inserting, deleting, or substituting individual or short stretches of bases. In many instances the mechanisms by which an organism recognizes the positions at which to edit or by which it performs the actual editing are unknown. One model system that stands out by its very high rate of on average one out of 25 bases being edited are the Myxomycetes, a class of slime molds. In this talk we will show how the computational methods and concepts from statistical Physics can be used to analyze DNA and protein sequence data to predict editing sites in these slime molds and to guide experiments that identified previously unknown types of editing as well as the complete set of editing events in the slime mold Physarum polycephalum.

Handbook of Adhesion, 2nd Edition

NASA Astrophysics Data System (ADS)

Packham, D. E.

2005-06-01

This second edition of the successful Handbook of Adhesion provides concise and authoritative articles covering many aspects of the science and technology associated with adhesion and adhesives. It is intended to fill a gap between the necessarily simplified treatment of the student textbook and the full and thorough treatment of the research monograph and review article. The articles are structured in such a way, with internal cross-referencing and external literature references, that the reader can build up a broader and deeper understanding, as their needs require. This second edition includes many new articles covering developments which have risen in prominence in the intervening years, such as scanning probe techniques, the surface forces apparatus and the relation between adhesion and fractal surfaces. Advances in understanding polymer - polymer interdiffusion are reflected in articles drawing out the implications for adhesive bonding. In addition, articles derived from the earlier edition have been revised and updated where needed. Throughout the book there is a renewed emphasis on environmental implications of the use of adhesives and sealants. The scope of the Handbook, which features nearly 250 articles from over 60 authors, includes the background science - physics, chemistry and material science - and engineering, and also aspects of adhesion relevant to the use of adhesives, including topics such as: Sealants and mastics Paints and coatings Printing and composite materials Welding and autohesion Engineering design The Handbook of Adhesion is intended for scientists and engineers in both academia and industry, requiring an understanding of the various facets of adhesion.

The universe, life, and intelligence (Sixth enlarged edition)

NASA Astrophysics Data System (ADS)

Shklovskii, Iosif Samuilovich

This classic work examines the possibility of the existence of life (including intelligent life) on other planetary systems. This enlarged edition includes essays on the search for extraterrestrial civilizations and the possibility of communication with intelligent beings on other planets.

Including Teachers in the Design of Collaborative Professional Development

ERIC Educational Resources Information Center

Jensen, Christopher M.

2014-01-01

Improving instruction has been shown to be among the best means of improving student achievement, and professional development has, in turn, been shown to be integral to improving instruction. Moreover, to be effective, professional development programs should be based on adult learning principles and incorporate teacher input. The problem serving…

Automatically Detecting Likely Edits in Clinical Notes Created Using Automatic Speech Recognition

PubMed Central

Lybarger, Kevin; Ostendorf, Mari; Yetisgen, Meliha

2017-01-01

The use of automatic speech recognition (ASR) to create clinical notes has the potential to reduce costs associated with note creation for electronic medical records, but at current system accuracy levels, post-editing by practitioners is needed to ensure note quality. Aiming to reduce the time required to edit ASR transcripts, this paper investigates novel methods for automatic detection of edit regions within the transcripts, including both putative ASR errors but also regions that are targets for cleanup or rephrasing. We create detection models using logistic regression and conditional random field models, exploring a variety of text-based features that consider the structure of clinical notes and exploit the medical context. Different medical text resources are used to improve feature extraction. Experimental results on a large corpus of practitioner-edited clinical notes show that 67% of sentence-level edits and 45% of word-level edits can be detected with a false detection rate of 15%. PMID:29854187

APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages

PubMed Central

Sharma, Shraddha; Patnaik, Santosh K.; Thomas Taggart, R.; Kannisto, Eric D.; Enriquez, Sally M.; Gollnick, Paul; Baysal, Bora E.

2015-01-01

The extent, regulation and enzymatic basis of RNA editing by cytidine deamination are incompletely understood. Here we show that transcripts of hundreds of genes undergo site-specific C>U RNA editing in macrophages during M1 polarization and in monocytes in response to hypoxia and interferons. This editing alters the amino acid sequences for scores of proteins, including many that are involved in pathogenesis of viral diseases. APOBEC3A, which is known to deaminate cytidines of single-stranded DNA and to inhibit viruses and retrotransposons, mediates this RNA editing. Amino acid residues of APOBEC3A that are known to be required for its DNA deamination and anti-retrotransposition activities were also found to affect its RNA deamination activity. Our study demonstrates the cellular RNA editing activity of a member of the APOBEC3 family of innate restriction factors and expands the understanding of C>U RNA editing in mammals. PMID:25898173

Preventing Prejudice: A Guide for Counselors, Educators, and Parents, Second Edition

ERIC Educational Resources Information Center

Ponterotto, Joseph G.; Utsey, Shawn O.; Pedersen, Paul B.

2006-01-01

This second edition has been completely revised and expanded to provide the most up-to-date and extensive coverage of prejudice and racism available. The new edition of this bestselling text presents a comprehensive overview of these topics and also includes practical tools for combating prejudice development in children, adolescents, and adults.…

Responses to Including Parents in Teacher Evaluation Policy: A Critical Policy Analysis

ERIC Educational Resources Information Center

Fernández, Erica; LeChasseur, Kimberly; Donaldson, Morgaen L.

2018-01-01

The intersection of development in family and school settings has been well established and education policies have begun to promote ways to bridge the two contexts (i.e. teacher evaluations). For this manuscript, authors focus on how teachers and principals used a state educator evaluation policy to position parents as authorities on education.…

Idaho Library Laws, 1996-1997. Full Edition.

ERIC Educational Resources Information Center

Idaho State Library, Boise.

This new edition of the "Idaho Library Laws" contains changes through the 1996 legislative session and includes "Idaho Code" sections that legally affect city, school-community or district libraries, or the Idaho State Library. These sections include the basic library laws in "Idaho Code" Title 33, Chapters 25, 26,…

The English Teacher's Survival Guide: Ready-To-Use Techniques & Materials for Grades 7-12. 2nd Edition

ERIC Educational Resources Information Center

Brandvik, Mary Lou; McKnight, Katherine S.

2011-01-01

This unique time-saving book is packed with tested techniques and materials to assist new and experienced English teachers with virtually every phase of their job from lesson planning to effective discipline techniques. The book includes 175 easy-to-understand strategies, lessons, checklists, and forms for effective classroom management and over…

Global analysis of A-to-I RNA editing reveals association with common disease variants

PubMed Central

Jain, Rajeev; Jain, Anamika; Betsholtz, Christer; Giannarelli, Chiara; Kovacic, Jason C.; Ruusalepp, Arno; Skogsberg, Josefin; Hao, Ke; Schadt, Eric E.