Sample records for technical advance identification

  1. Advanced Transportation System Studies Technical Area 2 (TA-2) Heavy Lift Launch Vehicle Development Contract. Volume 2; Technical Results

    NASA Technical Reports Server (NTRS)

    1995-01-01

    The purpose of the Advanced Transportation System Studies (ATSS) Technical Area 2 (TA-2) Heavy Lift Launch Vehicle Development contract was to provide advanced launch vehicle concept definition and analysis to assist NASA in the identification of future launch vehicle requirements. Contracted analysis activities included vehicle sizing and performance analysis, subsystem concept definition, propulsion subsystem definition (foreign and domestic), ground operations and facilities analysis, and life cycle cost estimation. This document is Volume 2 of the final report for the contract. It provides documentation of selected technical results from various TA-2 analysis activities, including a detailed narrative description of the SSTO concept assessment results, a user's guide for the associated SSTO sizing tools, an SSTO turnaround assessment report, an executive summary of the ground operations assessments performed during the first year of the contract, a configuration-independent vehicle health management system requirements report, a copy of all major TA-2 contract presentations, a copy of the FLO launch vehicle final report, and references to Pratt & Whitney's TA-2 sponsored final reports regarding the identification of Russian main propulsion technologies.

  2. Project T.E.A.M. (Technical Education Advancement Modules). Introduction to Statistical Process Control.

    ERIC Educational Resources Information Center

    Billings, Paul H.

    This instructional guide, one of a series developed by the Technical Education Advancement Modules (TEAM) project, is a 6-hour introductory module on statistical process control (SPC), designed to develop competencies in the following skill areas: (1) identification of the three classes of SPC use; (2) understanding a process and how it works; (3)…

  3. Advanced Small Modular Reactor (SMR) Probabilistic Risk Assessment (PRA) Technical Exchange Meeting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, Curtis

    2013-09-01

    During FY13, the INL developed an advanced SMR PRA framework which has been described in the report Small Modular Reactor (SMR) Probabilistic Risk Assessment (PRA) Detailed Technical Framework Specification, INL/EXT-13-28974 (April 2013). In this framework, the various areas are considered: Probabilistic models to provide information specific to advanced SMRs Representation of specific SMR design issues such as having co-located modules and passive safety features Use of modern open-source and readily available analysis methods Internal and external events resulting in impacts to safety All-hazards considerations Methods to support the identification of design vulnerabilities Mechanistic and probabilistic data needs to support modelingmore » and tools In order to describe this framework more fully and obtain feedback on the proposed approaches, the INL hosted a technical exchange meeting during August 2013. This report describes the outcomes of that meeting.« less

  4. Advance Identification (ADID)

    EPA Pesticide Factsheets

    Advance identification of disposal areas (ADID), a planning process used to identify wetlands and other waters that are generally suitable or unsuitable for the discharge of dredged and fill material.

  5. 47 CFR 80.231 - Technical Requirements for Class B Automatic Identification System (AIS) equipment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Identification System (AIS) equipment. 80.231 Section 80.231 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... § 80.231 Technical Requirements for Class B Automatic Identification System (AIS) equipment. (a) Class B Automatic Identification System (AIS) equipment must meet the technical requirements of IEC 62287...

  6. 47 CFR 80.231 - Technical Requirements for Class B Automatic Identification System (AIS) equipment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Identification System (AIS) equipment. 80.231 Section 80.231 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... § 80.231 Technical Requirements for Class B Automatic Identification System (AIS) equipment. (a) Class B Automatic Identification System (AIS) equipment must meet the technical requirements of IEC 62287...

  7. 47 CFR 80.231 - Technical Requirements for Class B Automatic Identification System (AIS) equipment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Identification System (AIS) equipment. 80.231 Section 80.231 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... § 80.231 Technical Requirements for Class B Automatic Identification System (AIS) equipment. (a) Class B Automatic Identification System (AIS) equipment must meet the technical requirements of IEC 62287...

  8. [The visual perception of the elements of technical drawings among masking distractions in advanced and nonadvanced students in the building and architectural professions].

    PubMed

    Balichev, Iu

    1997-01-01

    To investigation were submitted the particularities of the process of visual perception of technical drawings and schemes in advanced and backward pupils, who were mastering the specialties of "building and architecture", "hydroconstruction", "transport construction", "geodesy". The time was registered, which was necessary to advanced and backward pupils for unveiling the different elements in the drawing, scheme, and such attributes of the drawing as: orientation, length, curves of the lined, the boundary between them; time for identification of the specific designations, symbols, group of symbols, elements of the sketch from the simple to the complex ones. The results of the investigations revealed that in the advanced pupils the perception (unveiling) of the different elements of the technical drawing proceeded very rapidly, almost automatically. In the backward pupils this process elapsed reliably more slowly. It was demonstrated that the growing up pupils, who were distinguished with more rapid perception of the different elements of the drawing (advanced ones) more rapidly and more exactly dealt with solution of the technical tasks as compared with these, who more slowly unveiled the looked for elements (backwardness). Some other individual particularities were also established with respect to the visual perception of the elements of the technical drawing and its properties in advanced and backward pupils who were mastering the investigated professions.

  9. Project T.E.A.M. (Technical Education Advancement Modules). Advanced Statistical Process Control.

    ERIC Educational Resources Information Center

    Dunlap, Dale

    This instructional guide, one of a series developed by the Technical Education Advancement Modules (TEAM) project, is a 20-hour advanced statistical process control (SPC) and quality improvement course designed to develop the following competencies: (1) understanding quality systems; (2) knowing the process; (3) solving quality problems; and (4)…

  10. Advanced Technical Drafting (Industrial Arts) Curriculum Guide. Bulletin 1751.

    ERIC Educational Resources Information Center

    Louisiana State Dept. of Education, Baton Rouge. Div. of Vocational Education.

    This curriculum guide contains materials for a 17-unit course in advanced technical drafting, a followup to the basic technical drafting course in the industrial arts curriculum for grades 10-12. It is intended for use by industrial arts teachers, supervisors, counselors, administrators, and teacher educators. A three-page course overview provides…

  11. Advanced Public Transportation Systems. Technical Assistance Brief 2

    DOT National Transportation Integrated Search

    1993-01-01

    The Advanced Public Transportation Systems (APTS) Program requires evaluation : of pilot projects. This technical assistance brief discusses the guidelines set : for developing evaluation framework and methodology for local projects. 4p.

  12. Project T.E.A.M. (Technical Education Advancement Modules). Final Report.

    ERIC Educational Resources Information Center

    Greenville Technical Coll., SC.

    Project TEAM (Technical Education Advancement Modules), a cooperative demonstration program for high technology training, created an introductory technical training program and a consumer education package emphasizing the benefits of technical training. The curriculum and training focus of the project began with an assessment of employee needs in…

  13. An overview of recent advances in system identification

    NASA Technical Reports Server (NTRS)

    Juang, Jer-Nan

    1994-01-01

    This paper presents an overview of the recent advances in system identification for modal testing and control of large flexible structures. Several techniques are discussed including the Observer/Kalman Filter Identification, the Observer/Controller Identification, and the State-Space System Identification in the Frequency Domain. The System/Observer/Controller Toolbox developed at NASA Langley Research Center is used to show the applications of these techniques to real aerospace structures such as the Hubble spacecraft telescope and the active flexible aircraft wing.

  14. 47 CFR 80.275 - Technical Requirements for Class A Automatic Identification System (AIS) equipment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Compulsory Ships § 80.275 Technical Requirements for Class A Automatic Identification System (AIS) equipment. (a) Prior to submitting a certification application for a Class A AIS device, the following... Identification System (AIS) equipment. 80.275 Section 80.275 Telecommunication FEDERAL COMMUNICATIONS COMMISSION...

  15. 47 CFR 80.275 - Technical Requirements for Class A Automatic Identification System (AIS) equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Compulsory Ships § 80.275 Technical Requirements for Class A Automatic Identification System (AIS) equipment. (a) Prior to submitting a certification application for a Class A AIS device, the following... Identification System (AIS) equipment. 80.275 Section 80.275 Telecommunication FEDERAL COMMUNICATIONS COMMISSION...

  16. 47 CFR 80.275 - Technical Requirements for Class A Automatic Identification System (AIS) equipment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Compulsory Ships § 80.275 Technical Requirements for Class A Automatic Identification System (AIS) equipment. (a) Prior to submitting a certification application for a Class A AIS device, the following... Identification System (AIS) equipment. 80.275 Section 80.275 Telecommunication FEDERAL COMMUNICATIONS COMMISSION...

  17. 47 CFR 80.275 - Technical Requirements for Class A Automatic Identification System (AIS) equipment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Compulsory Ships § 80.275 Technical Requirements for Class A Automatic Identification System (AIS) equipment. (a) Prior to submitting a certification application for a Class A AIS device, the following... Identification System (AIS) equipment. 80.275 Section 80.275 Telecommunication FEDERAL COMMUNICATIONS COMMISSION...

  18. Searching for the elusive gift: advances in talent identification in sport.

    PubMed

    Mann, David L; Dehghansai, Nima; Baker, Joseph

    2017-08-01

    The incentives for sport organizations to identify talented athletes from a young age continue to grow, yet effective talent identification remains a challenging task. This opinion paper examines recent advances in talent identification, focusing in particular on the emergence of new approaches that may offer promise to identify talent (e.g., small-sided games, genetic testing, and advanced statistical analyses). We appraise new multi-disciplinary and large-scale population studies of talent identification, provide a consideration of the most recent psychological predictors of performance, examine the emergence of new approaches that strive to diminish biases in talent identification, and look at the rise in interest in talent identification in Paralympic sport. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

  19. 9 CFR 351.11 - Identification and separation of technical animal fats for certification and materials for use...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... technical animal fats for certification and materials for use therein; removal of wrappers, etc.; cleaning... AND VOLUNTARY INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Facilities and Operations § 351.11 Identification and separation of technical animal fats for certification...

  20. 9 CFR 351.11 - Identification and separation of technical animal fats for certification and materials for use...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... technical animal fats for certification and materials for use therein; removal of wrappers, etc.; cleaning... AND VOLUNTARY INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Facilities and Operations § 351.11 Identification and separation of technical animal fats for certification...

  1. 9 CFR 351.11 - Identification and separation of technical animal fats for certification and materials for use...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... technical animal fats for certification and materials for use therein; removal of wrappers, etc.; cleaning... AND VOLUNTARY INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Facilities and Operations § 351.11 Identification and separation of technical animal fats for certification...

  2. 9 CFR 351.11 - Identification and separation of technical animal fats for certification and materials for use...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... technical animal fats for certification and materials for use therein; removal of wrappers, etc.; cleaning... AND VOLUNTARY INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Facilities and Operations § 351.11 Identification and separation of technical animal fats for certification...

  3. 9 CFR 351.11 - Identification and separation of technical animal fats for certification and materials for use...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... technical animal fats for certification and materials for use therein; removal of wrappers, etc.; cleaning... AND VOLUNTARY INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Facilities and Operations § 351.11 Identification and separation of technical animal fats for certification...

  4. Center for Advanced Space Propulsion Second Annual Technical Symposium Proceedings

    NASA Technical Reports Server (NTRS)

    1990-01-01

    The proceedings for the Center for Advanced Space Propulsion Second Annual Technical Symposium are divided as follows: Chemical Propulsion, CFD; Space Propulsion; Electric Propulsion; Artificial Intelligence; Low-G Fluid Management; and Rocket Engine Materials.

  5. Technical management techniques for identification and control of industrial safety and pollution hazards

    NASA Technical Reports Server (NTRS)

    Campbell, R.; Dyer, M. K.; Hoard, E. G.; Little, D. G.; Taylor, A. C.

    1972-01-01

    Constructive recommendations are suggested for pollution problems from offshore energy resources industries on outer continental shelf. Technical management techniques for pollution identification and control offer possible applications to space engineering and management.

  6. Advanced Infantry Training: An Empirical Analysis Of (0341) Mortarman Success While Attending Advanced Mortarman Course

    DTIC Science & Technology

    2017-12-01

    13 Table 2. TFDW File Descriptions ... evaluation FO Forward Observer FY Fiscal year GT General technical HLZ Helicopter landing zone ID Identification ITB Infantry Training...survive during AMCs most difficult training phases, to include FDC and advanced FDC evaluations . These events require a heightened degree of cognitive

  7. 48 CFR 227.7103-3 - Early identification of technical data to be furnished to the Government with restrictions on use...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Early identification of technical data to be furnished to the Government with restrictions on use, reproduction or disclosure. 227... 227.7103-3 Early identification of technical data to be furnished to the Government with restrictions...

  8. 48 CFR 227.7103-3 - Early identification of technical data to be furnished to the Government with restrictions on use...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Early identification of technical data to be furnished to the Government with restrictions on use, reproduction or disclosure. 227... 227.7103-3 Early identification of technical data to be furnished to the Government with restrictions...

  9. 48 CFR 227.7103-10 - Contractor identification and marking of technical data to be furnished with restrictive markings.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... and marking of technical data to be furnished with restrictive markings. 227.7103-10 Section 227.7103... DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Technical Data 227.7103-10 Contractor identification and marking of technical data to be furnished with restrictive markings...

  10. Project T.E.A.M. (Technical Education Advancement Modules). Introduction to Industrial Physics.

    ERIC Educational Resources Information Center

    Whisenhunt, James E.

    This instructional guide, one of a series developed by the Technical Education Advancement Modules (TEAM) project, is a 20-hour introduction to industrial physics that explains and demonstrates to industrial maintenance mechanics the direct relationship of physics to machinery. Project TEAM is intended to upgrade basic technical competencies of…

  11. Project T.E.A.M. (Technical Education Advancement Modules). Fundementals of Workplace Integration.

    ERIC Educational Resources Information Center

    Kraeling, Vicki

    This module is one of a series of instructional guides developed by Project TEAM (Technical Education Advancement Modules), a cooperative demonstration program for high technology training for unemployed, underemployed, and existing industrial employees whose basic technical skills are in need of upgrading. The module is a 27-hour overview course…

  12. Technical advances in flow cytometry-based diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria

    PubMed Central

    Correia, Rodolfo Patussi; Bento, Laiz Cameirão; Bortolucci, Ana Carolina Apelle; Alexandre, Anderson Marega; Vaz, Andressa da Costa; Schimidell, Daniela; Pedro, Eduardo de Carvalho; Perin, Fabricio Simões; Nozawa, Sonia Tsukasa; Mendes, Cláudio Ernesto Albers; Barroso, Rodrigo de Souza; Bacal, Nydia Strachman

    2016-01-01

    ABSTRACT Objective: To discuss the implementation of technical advances in laboratory diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria for validation of high-sensitivity flow cytometry protocols. Methods: A retrospective study based on analysis of laboratory data from 745 patient samples submitted to flow cytometry for diagnosis and/or monitoring of paroxysmal nocturnal hemoglobinuria. Results: Implementation of technical advances reduced test costs and improved flow cytometry resolution for paroxysmal nocturnal hemoglobinuria clone detection. Conclusion: High-sensitivity flow cytometry allowed more sensitive determination of paroxysmal nocturnal hemoglobinuria clone type and size, particularly in samples with small clones. PMID:27759825

  13. Advanced transportation system studies technical area 2(TA-2): Heavy lift launch vehicle development. volume 1; Executive summary

    NASA Technical Reports Server (NTRS)

    McCurry, J.

    1995-01-01

    The purpose of the TA-2 contract was to provide advanced launch vehicle concept definition and analysis to assist NASA in the identification of future launch vehicle requirements. Contracted analysis activities included vehicle sizing and performance analysis, subsystem concept definition, propulsion subsystem definition (foreign and domestic), ground operations and facilities analysis, and life cycle cost estimation. This document is part of the final report for the TA-2 contract. The final report consists of three volumes: Volume 1 is the Executive Summary, Volume 2 is Technical Results, and Volume 3 is Program Cost Estimates. The document-at-hand, Volume 1, provides a summary description of the technical activities that were performed over the entire contract duration, covering three distinct launch vehicle definition activities: heavy-lift (300,000 pounds injected mass to low Earth orbit) launch vehicles for the First Lunar Outpost (FLO), medium-lift (50,000-80,000 pounds injected mass to low Earth orbit) launch vehicles, and single-stage-to-orbit (SSTO) launch vehicles (25,000 pounds injected mass to a Space Station orbit).

  14. Advanced ultrasonic measurement methodology for non-invasive interrogation and identification of fluids in sealed containers

    NASA Astrophysics Data System (ADS)

    Tucker, Brian J.; Diaz, Aaron A.; Eckenrode, Brian A.

    2006-03-01

    Government agencies and homeland security related organizations have identified the need to develop and establish a wide range of unprecedented capabilities for providing scientific and technical forensic services to investigations involving hazardous chemical, biological, and radiological materials, including extremely dangerous chemical and biological warfare agents. Pacific Northwest National Laboratory (PNNL) has developed a prototype portable, hand-held, hazardous materials acoustic inspection prototype that provides noninvasive container interrogation and material identification capabilities using nondestructive ultrasonic velocity and attenuation measurements. Due to the wide variety of fluids as well as container sizes and materials encountered in various law enforcement inspection activities, the need for high measurement sensitivity and advanced ultrasonic measurement techniques were identified. The prototype was developed using a versatile electronics platform, advanced ultrasonic wave propagation methods, and advanced signal processing techniques. This paper primarily focuses on the ultrasonic measurement methods and signal processing techniques incorporated into the prototype. High bandwidth ultrasonic transducers combined with an advanced pulse compression technique allowed researchers to 1) obtain high signal-to-noise ratios and 2) obtain accurate and consistent time-of-flight (TOF) measurements through a variety of highly attenuative containers and fluid media. Results of work conducted in the laboratory have demonstrated that the prototype experimental measurement technique also provided information regarding container properties, which will be utilized in future container-independent measurements of hidden liquids.

  15. Colorectal endoscopic submucosal dissection: Recent technical advances for safe and successful procedures

    PubMed Central

    Yamamoto, Katsumi; Michida, Tomoki; Nishida, Tsutomu; Hayashi, Shiro; Naito, Masafumi; Ito, Toshifumi

    2015-01-01

    Endoscopic submucosal dissection (ESD) is very useful in en bloc resection of large superficial colorectal tumors but is a technically difficult procedure because the colonic wall is thin and endoscopic maneuverability is poor because of colonic flexure and extensibility. A high risk of perforation has been reported in colorectal ESD. To prevent complications such as perforation and unexpected bleeding, it is crucial to ensure good visualization of the submucosal layer by creating a mucosal flap, which is an exfoliated mucosa for inserting the tip of the endoscope under it. The creation of a mucosal flap is often technically difficult; however, various types of equipment, appropriate strategy, and novel procedures including our clip-flap method, appear to facilitate mucosal flap creation, improving the safety and success rate of ESD. Favorable treatment outcomes with colorectal ESD have already been reported in many advanced institutions, and appropriate understanding of techniques and development of training systems are required for world-wide standardization of colorectal ESD. Here, we describe recent technical advances for safe and successful colorectal ESD. PMID:26468335

  16. Technical Support Services for the Office of Naval Research Littoral Warfare Advanced Development Project

    DTIC Science & Technology

    2005-09-30

    Technical Support Services for the Office of Naval Research Littoral Warfare Advanced Development Project William R. Metzger Marine...Support Services for the Office of Naval Research Littoral Warfare Advanced Development Project 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT

  17. 40 CFR 230.80 - Advanced identification of disposal areas.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Advanced identification of disposal areas. 230.80 Section 230.80 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN... from approved Coastal Zone Management programs and River Basin Plans; (e) The permitting authority...

  18. 40 CFR 230.80 - Advanced identification of disposal areas.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Advanced identification of disposal areas. 230.80 Section 230.80 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN... from approved Coastal Zone Management programs and River Basin Plans; (e) The permitting authority...

  19. 40 CFR 230.80 - Advanced identification of disposal areas.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Advanced identification of disposal areas. 230.80 Section 230.80 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN... from approved Coastal Zone Management programs and River Basin Plans; (e) The permitting authority...

  20. 40 CFR 230.80 - Advanced identification of disposal areas.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Advanced identification of disposal areas. 230.80 Section 230.80 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN... from approved Coastal Zone Management programs and River Basin Plans; (e) The permitting authority...

  1. 40 CFR 230.80 - Advanced identification of disposal areas.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Advanced identification of disposal areas. 230.80 Section 230.80 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN... from approved Coastal Zone Management programs and River Basin Plans; (e) The permitting authority...

  2. 48 CFR 227.7103-3 - Early identification of technical data to be furnished to the Government with restrictions on use...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... technical data to be furnished to the Government with restrictions on use, reproduction or disclosure. 227..., DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Technical Data 227.7103-3 Early identification of technical data to be furnished to the Government with restrictions...

  3. 48 CFR 227.7103-3 - Early identification of technical data to be furnished to the Government with restrictions on use...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... technical data to be furnished to the Government with restrictions on use, reproduction or disclosure. 227..., DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Technical Data 227.7103-3 Early identification of technical data to be furnished to the Government with restrictions...

  4. 48 CFR 227.7103-3 - Early identification of technical data to be furnished to the Government with restrictions on use...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... technical data to be furnished to the Government with restrictions on use, reproduction or disclosure. 227..., DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Technical Data 227.7103-3 Early identification of technical data to be furnished to the Government with restrictions...

  5. Advanced Ultrasonic Measurement Methodology for Non-Invasive Interrogation and Identification of Fluids in Sealed Containers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tucker, Brian J.; Diaz, Aaron A.; Eckenrode, Brian A.

    2006-03-16

    The Hazardous Materials Response Unit (HMRU) and the Counterterrorism and Forensic Science Research Unit (CTFSRU), Laboratory Division, Federal Bureau of Investigation (FBI) have been mandated to develop and establish a wide range of unprecedented capabilities for providing scientific and technical forensic services to investigations involving hazardous chemical, biological, and radiological materials, including extremely dangerous chemical and biological warfare agents. Pacific Northwest National Laboratory (PNNL) has developed a portable, hand-held, hazardous materials acoustic inspection device (HAZAID) that provides noninvasive container interrogation and material identification capabilities using nondestructive ultrasonic velocity and attenuation measurements. Due to the wide variety of fluids as wellmore » as container sizes and materials, the need for high measurement sensitivity and advanced ultrasonic measurement techniques were identified. The HAZAID prototype was developed using a versatile electronics platform, advanced ultrasonic wave propagation methods, and advanced signal processing techniques. This paper primarily focuses on the ultrasonic measurement methods and signal processing techniques incorporated into the HAZAID prototype. High bandwidth ultrasonic transducers combined with the advanced pulse compression technique allowed researchers to 1) impart large amounts of energy, 2) obtain high signal-to-noise ratios, and 3) obtain accurate and consistent time-of-flight (TOF) measurements through a variety of highly attenuative containers and fluid media. Results of this feasibility study demonstrated that the HAZAID experimental measurement technique also provided information regarding container properties, which will be utilized in future container-independent measurements of hidden liquids.« less

  6. [Isolation and identification methods of enterobacteria group and its technological advancement].

    PubMed

    Furuta, Itaru

    2007-08-01

    In the last half-century, isolation and identification methods of enterobacteria groups have markedly improved by technological advancement. Clinical microbiology tests have changed overtime from tube methods to commercial identification kits and automated identification. Tube methods are the original method for the identification of enterobacteria groups, that is, a basically essential method to recognize bacterial fermentation and biochemical principles. In this paper, traditional tube tests are discussed, such as the utilization of carbohydrates, indole, methyl red, and citrate and urease tests. Commercial identification kits and automated instruments by computer based analysis as current methods are also discussed, and those methods provide rapidity and accuracy. Nonculture techniques of nucleic acid typing methods using PCR analysis, and immunochemical methods using monoclonal antibodies can be further developed.

  7. The Metropolitan Advanced Technical Magnet High School: 1990-1991. Formative Evaluation.

    ERIC Educational Resources Information Center

    Seever, Mark L.

    This report evaluates the implementation of the "Long-Range Magnet School Plan" at Metropolitan Advanced Technical Magnet High School in Kansas City, Missouri for academic year 1990-91. Introductory sections describe the program, and the evaluation design and methodology. Results on enrollment indicated that only ninth and tenth grades…

  8. Advanced transportation system studies technical area 3: Alternate propulsion subsystem concepts, volume 3

    NASA Technical Reports Server (NTRS)

    Levak, Daniel

    1993-01-01

    The objective of this contract was to provide definition of alternate propulsion systems for both earth-to-orbit (ETO) and in-space vehicles (upper stages and space transfer vehicles). For such propulsion systems, technical data to describe performance, weight, dimensions, etc. was provided along with programmatic information such as cost, schedule, needed facilities, etc. Advanced technology and advanced development needs were determined and provided. This volume separately presents the various program cost estimates that were generated under three tasks: the F-1A Restart Task, the J-2S Restart Task, and the SSME Upper Stage Use Task. The conclusions, technical results, and the program cost estimates are described in more detail in Volume 1 - Executive Summary and in individual Final Task Reports.

  9. 47 CFR 80.275 - Technical Requirements for Class A Automatic Identification System (AIS) equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Technical Requirements for Class A Automatic Identification System (AIS) equipment. 80.275 Section 80.275 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Equipment Authorization for Compulsory Ships § 80.275...

  10. Advanced missions safety. Volume 2: Technical discussion, Part 2: Experiment safety, guidelines

    NASA Technical Reports Server (NTRS)

    Hinton, M. G., Jr.

    1972-01-01

    A technical analysis of a portion of the advanced missions safety study is presented. The potential hazards introduced when experimental equipment is carried aboard the Earth Orbit Shuttle are identified. Safety guidelines and requirements for eliminating or reducing these hazards are recommended.

  11. Thyroid nodule ultrasound: technical advances and future horizons.

    PubMed

    McQueen, Andrew S; Bhatia, Kunwar S S

    2015-04-01

    Thyroid nodules are extremely common and the vast majority are non-malignant; therefore the accurate discrimination of a benign lesion from malignancy is challenging. Ultrasound (US) characterisation has become the key component of many thyroid nodule guidelines and is primarily based on the detection of key features by high-resolution US. The thyroid imager should be familiar with the strengths and limitations of this modality and understand the technical factors that create and alter the imaging characteristics. Specific advances in high-resolution US are discussed with reference to individual features of thyroid cancer and benign disease. Potential roles for three-dimensional thyroid ultrasound and computer-aided diagnosis are also considered. The second section provides an overview of current evidence regarding thyroid ultrasound elastography (USE). USE is a novel imaging technique that quantifies tissue elasticity (stiffness) non-invasively and has potential utility because cancers cause tissue stiffening. In recent years, there has been much research into the value of thyroid USE for distinguishing benign and malignant nodules. Preliminary findings from multiple pilot studies and meta-analyses are promising and suggest that USE can augment the anatomical detail provided by high-resolution US. However, a definite role remains controversial and is discussed. • High-resolution US characterises thyroid nodules by demonstration of specific anatomical features • Technical advances heavily influence the key US features of thyroid nodules • Most papillary carcinomas appear stiffer than benign thyroid nodules on US elastography (USE) • Thyroid USE is controversial because of variation in the reported accuracies for malignancy • Combined grey-scale US/USE may lower the FNAC rate in benign nodules.

  12. Advances in addressing technical challenges of point-of-care diagnostics in resource-limited settings

    PubMed Central

    Wang, ShuQi; Lifson, Mark A.; Inci, Fatih; Liang, Li-Guo; Sheng, Ye-Feng; Demirci, Utkan

    2016-01-01

    The striking prevalence of HIV, TB and malaria, as well as outbreaks of emerging infectious diseases, such as influenza A (H7N9), Ebola and MERS, poses great challenges for patient care in resource-limited settings (RLS). However, advanced diagnostic technologies cannot be implemented in RLS largely due to economic constraints. Simple and inexpensive point-of-care (POC) diagnostics, which rely less on environmental context and operator training, have thus been extensively studied to achieve early diagnosis and treatment monitoring in non-laboratory settings. Despite great input from material science, biomedical engineering and nanotechnology for developing POC diagnostics, significant technical challenges are yet to be overcome. Summarized here are the technical challenges associated with POC diagnostics from a RLS perspective and the latest advances in addressing these challenges are reviewed. PMID:26777725

  13. Portal vein territory identification using indocyanine green fluorescence imaging: Technical details and short-term outcomes.

    PubMed

    Kobayashi, Yuta; Kawaguchi, Yoshikuni; Kobayashi, Kosuke; Mori, Kazuhiro; Arita, Junichi; Sakamoto, Yoshihiro; Hasegawa, Kiyoshi; Kokudo, Norihiro

    2017-12-01

    Portal vein (PV) territory identification during liver resection may be performed using indocyanine green (ICG) fluorescence imaging technique. However, the technical details of the fluorescence staining technique have not been fully elucidated. This study was performed to demonstrate the technical details of PV territory identification using fluorescence imaging and evaluates the short-term outcomes. From 2011 to 2015, 105 underwent liver resection at the University of Tokyo Hospital with one of the following fluorescence staining techniques by transhepatic PV injection or intravenous injection of ICG: single staining (n = 36), multiple staining (n = 31), counterstaining (n = 22), negative staining (n = 13), or paradoxical negative staining (n = 3). The PV territory was identified as a region with fluorescence or a defect of fluorescence using one of the five staining techniques. ICG was administered by transhepatic PV injection in all but the negative staining technique, which employed intravenous injection. No adverse events associated with the ICG administration occurred. The mortality, postoperative total morbidity, and the major complication (Clavien-Dindo grade ≥III) rates were 0.0%, 14.3%, and 7.6%. We have demonstrated the technical details of five types of fluorescence staining techniques. These techniques are safe to perform and facilitate clear visualization of the PV territory in real time, enhancing the efficacy of anatomical removal of such territories. © 2017 Wiley Periodicals, Inc.

  14. Proteomic Workflows for Biomarker Identification Using Mass Spectrometry — Technical and Statistical Considerations during Initial Discovery

    PubMed Central

    Orton, Dennis J.; Doucette, Alan A.

    2013-01-01

    Identification of biomarkers capable of differentiating between pathophysiological states of an individual is a laudable goal in the field of proteomics. Protein biomarker discovery generally employs high throughput sample characterization by mass spectrometry (MS), being capable of identifying and quantifying thousands of proteins per sample. While MS-based technologies have rapidly matured, the identification of truly informative biomarkers remains elusive, with only a handful of clinically applicable tests stemming from proteomic workflows. This underlying lack of progress is attributed in large part to erroneous experimental design, biased sample handling, as well as improper statistical analysis of the resulting data. This review will discuss in detail the importance of experimental design and provide some insight into the overall workflow required for biomarker identification experiments. Proper balance between the degree of biological vs. technical replication is required for confident biomarker identification. PMID:28250400

  15. Drawing on Technical Writing Scholarship for the Teaching of Writing to Advanced ESL Students--A Writing Tutorial.

    ERIC Educational Resources Information Center

    Zielinska, Dorota

    2003-01-01

    Outlines the technical writing tutorial (TWT) that precedes an advanced English as a second language (ESL) writing course for students of English Philology at the Jagiellonian University, Poland. Finds a statistically significant increase in the performance of the students who had taken the TWT. Indicates that technical writing books and journals…

  16. Advancing Commercialization of Algal Biofuel through Increased Biomass Productivity and Technical Integration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Anton, David

    The proposed project built on the foundation of over several years years of intensive and ground-breaking R&D work at Cellana's Kona Demonstration Facility (KDF). Phycological and engineering solutions were provided to tackle key cultivation issues and technical barriers limiting algal biomass productivity identified through work conducted outdoors at industrial (1 acre) scale. The objectives of this project were to significantly improve algal biomass productivity and reduce operational cost in a seawater-based system, using results obtained from two top-performing algal strains as the baseline while technically advancing and more importantly, integrating the various unit operations involved in algal biomass production, processing,more » and refining.« less

  17. Dental DNA fingerprinting in identification of human remains

    PubMed Central

    Girish, KL; Rahman, Farzan S; Tippu, Shoaib R

    2010-01-01

    The recent advances in molecular biology have revolutionized all aspects of dentistry. DNA, the language of life yields information beyond our imagination, both in health or disease. DNA fingerprinting is a tool used to unravel all the mysteries associated with the oral cavity and its manifestations during diseased conditions. It is being increasingly used in analyzing various scenarios related to forensic science. The technical advances in molecular biology have propelled the analysis of the DNA into routine usage in crime laboratories for rapid and early diagnosis. DNA is an excellent means for identification of unidentified human remains. As dental pulp is surrounded by dentin and enamel, which forms dental armor, it offers the best source of DNA for reliable genetic type in forensic science. This paper summarizes the recent literature on use of this technique in identification of unidentified human remains. PMID:21731342

  18. Advanced Transportation System Studies. Technical Area 3: Alternate Propulsion Subsystems Concepts. Volume 3; Program Cost Estimates

    NASA Technical Reports Server (NTRS)

    Levack, Daniel J. H.

    2000-01-01

    The objective of this contract was to provide definition of alternate propulsion systems for both earth-to-orbit (ETO) and in-space vehicles (upper stages and space transfer vehicles). For such propulsion systems, technical data to describe performance, weight, dimensions, etc. was provided along with programmatic information such as cost, schedule, needed facilities, etc. Advanced technology and advanced development needs were determined and provided. This volume separately presents the various program cost estimates that were generated under three tasks: the F- IA Restart Task, the J-2S Restart Task, and the SSME Upper Stage Use Task. The conclusions, technical results , and the program cost estimates are described in more detail in Volume I - Executive Summary and in individual Final Task Reports.

  19. NASA Technical Interchange Meeting (TIM): Advanced Technology Lifecycle Analysis System (ATLAS) Technology Tool Box

    NASA Technical Reports Server (NTRS)

    ONeil, D. A.; Craig, D. A.; Christensen, C. B.; Gresham, E. C.

    2005-01-01

    The objective of this Technical Interchange Meeting was to increase the quantity and quality of technical, cost, and programmatic data used to model the impact of investing in different technologies. The focus of this meeting was the Technology Tool Box (TTB), a database of performance, operations, and programmatic parameters provided by technologists and used by systems engineers. The TTB is the data repository used by a system of models known as the Advanced Technology Lifecycle Analysis System (ATLAS). This report describes the result of the November meeting, and also provides background information on ATLAS and the TTB.

  20. Advanced Risk Reduction Tool (ARRT) Special Case Study Report: Science and Engineering Technical Assessments (SETA) Program

    NASA Technical Reports Server (NTRS)

    Kirsch, Paul J.; Hayes, Jane; Zelinski, Lillian

    2000-01-01

    This special case study report presents the Science and Engineering Technical Assessments (SETA) team's findings for exploring the correlation between the underlying models of Advanced Risk Reduction Tool (ARRT) relative to how it identifies, estimates, and integrates Independent Verification & Validation (IV&V) activities. The special case study was conducted under the provisions of SETA Contract Task Order (CTO) 15 and the approved technical approach documented in the CTO-15 Modification #1 Task Project Plan.

  1. Advanced Platform Systems Technology study. Volume 3: Supporting data

    NASA Technical Reports Server (NTRS)

    1983-01-01

    The overall study effort proceeded from the identification of 106 technology topics to the selection of 5 for detail trade studies. The technical issues and options were evaluated through the trade process. Finally, individual consideration was given to costs and benefits for the technologies identified for advancement. Eight priority technology items were identified for advancement. Supporting data generated during the trade selection and trade study process were presented. Space platform requirements, trade study and cost benefits analysis, and technology advancement planning are advanced. The structured approach used took advantage of a number of forms developed to ensure that a consistent approach was employed by each of the diverse specialists that participated. These forms were an intrinsic part of the study protocol.

  2. Why and How to Advance Technical Copywriting.

    ERIC Educational Resources Information Center

    Henson, Leigh

    1996-01-01

    States that promotional writing for industrial/high-tech products, or technical copywriting, is gaining more attention in technical communication, although it is neglected in higher education. Testifies to the significance of technical copywriting. Suggests that dialogical audience analysis and an emphasis on rational appeal will contribute to…

  3. Advances in Raman spectroscopy for explosive identification in aviation security

    NASA Astrophysics Data System (ADS)

    Santillán, Javier D.; Brown, Christopher D.; Jalenak, Wayne

    2007-04-01

    In the operational airport environment, the rapid identification of potentially hazardous materials such as improvised explosive devices, chemical warfare agents and flammable and explosive liquids is increasingly critical. Peroxide-based explosives pose a particularly insidious threat because they can be made from commonly available and relatively innocuous household chemicals, such as bleach and hydrogen peroxide. Raman spectroscopy has been validated as a valuable tool for rapid identification of chemicals, explosives, and narcotics and their precursors while allowing "line-of-sight" interrogation through bottles or other translucent containers. This enables safe identification of both precursor substances, such as acetone, and end-products, such as TATP, without direct sampling, contamination and exposure by security personnel. To date, Raman systems have been laboratory-based, requiring careful operation and maintenance by technology experts. The capital and ongoing expenses of these systems is also significant. Recent advances in Raman component technologies have dramatically reduced the footprint and cost, while improving the reliability and ease of use of Raman spectroscopy systems. Such technologies are not only bringing the lab to the field, but are also protecting civilians and security personnel in the process.

  4. Advanced transportation system studies technical area 2 (TA-2): Heavy lift launch vehicle development. volume 3; Program Cost estimates

    NASA Technical Reports Server (NTRS)

    McCurry, J. B.

    1995-01-01

    The purpose of the TA-2 contract was to provide advanced launch vehicle concept definition and analysis to assist NASA in the identification of future launch vehicle requirements. Contracted analysis activities included vehicle sizing and performance analysis, subsystem concept definition, propulsion subsystem definition (foreign and domestic), ground operations and facilities analysis, and life cycle cost estimation. The basic period of performance of the TA-2 contract was from May 1992 through May 1993. No-cost extensions were exercised on the contract from June 1993 through July 1995. This document is part of the final report for the TA-2 contract. The final report consists of three volumes: Volume 1 is the Executive Summary, Volume 2 is Technical Results, and Volume 3 is Program Cost Estimates. The document-at-hand, Volume 3, provides a work breakdown structure dictionary, user's guide for the parametric life cycle cost estimation tool, and final report developed by ECON, Inc., under subcontract to Lockheed Martin on TA-2 for the analysis of heavy lift launch vehicle concepts.

  5. Final Technical Report - Center for Technology for Advanced Scientific Component Software (TASCS)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sussman, Alan

    2014-10-21

    This is a final technical report for the University of Maryland work in the SciDAC Center for Technology for Advanced Scientific Component Software (TASCS). The Maryland work focused on software tools for coupling parallel software components built using the Common Component Architecture (CCA) APIs. Those tools are based on the Maryland InterComm software framework that has been used in multiple computational science applications to build large-scale simulations of complex physical systems that employ multiple separately developed codes.

  6. Fieldcrest Cannon, Inc. Advanced Technical Preparation. Statistical Process Control (SPC). PRE-SPC I. Instructor Book.

    ERIC Educational Resources Information Center

    Averitt, Sallie D.

    This instructor guide, which was developed for use in a manufacturing firm's advanced technical preparation program, contains the materials required to present a learning module that is designed to prepare trainees for the program's statistical process control module by improving their basic math skills and instructing them in basic calculator…

  7. Data Mining and Predictive Modeling in Institutional Advancement: How Ten Schools Found Success. Technical Report

    ERIC Educational Resources Information Center

    Luperchio, Dan

    2009-01-01

    This technical report, produced in partnership by the Council for Advancement and Support of Education (CASE) and SPSS Inc., explores the promise of data mining alumni records at educational institutions. Working with individual alumni records from The Johns Hopkins Zanvyl Krieger School of Arts and Sciences, a predictive regression model is…

  8. Advances in DNA metabarcoding for food and wildlife forensic species identification.

    PubMed

    Staats, Martijn; Arulandhu, Alfred J; Gravendeel, Barbara; Holst-Jensen, Arne; Scholtens, Ingrid; Peelen, Tamara; Prins, Theo W; Kok, Esther

    2016-07-01

    Species identification using DNA barcodes has been widely adopted by forensic scientists as an effective molecular tool for tracking adulterations in food and for analysing samples from alleged wildlife crime incidents. DNA barcoding is an approach that involves sequencing of short DNA sequences from standardized regions and comparison to a reference database as a molecular diagnostic tool in species identification. In recent years, remarkable progress has been made towards developing DNA metabarcoding strategies, which involves next-generation sequencing of DNA barcodes for the simultaneous detection of multiple species in complex samples. Metabarcoding strategies can be used in processed materials containing highly degraded DNA e.g. for the identification of endangered and hazardous species in traditional medicine. This review aims to provide insight into advances of plant and animal DNA barcoding and highlights current practices and recent developments for DNA metabarcoding of food and wildlife forensic samples from a practical point of view. Special emphasis is placed on new developments for identifying species listed in the Convention on International Trade of Endangered Species (CITES) appendices for which reliable methods for species identification may signal and/or prevent illegal trade. Current technological developments and challenges of DNA metabarcoding for forensic scientists will be assessed in the light of stakeholders' needs.

  9. Dryland ecohydrology and climate change: critical issues and technical advances

    NASA Astrophysics Data System (ADS)

    Wang, L.; D'Odorico, P.; Evans, J. P.; Eldridge, D.; McCabe, M. F.; Caylor, K. K.; King, E. G.

    2012-04-01

    Drylands cover about 40% of the terrestrial land surface and account for approximately 40% of global net primary productivity. Water is fundamental to the biophysical processes that sustain ecosystem function and food production, particularly in drylands, where a tight coupling exists between water resource availability and ecosystem productivity, surface energy balance, and biogeochemical cycles. Currently, drylands support at least 2 billion people and comprise both natural and managed ecosystems. In this synthesis, we identify some current critical issues in the understanding of dryland systems and discuss how arid and semiarid environments are responding to the changes in climate and land use. Specifically, we focus on dryland agriculture and food security, dryland population growth, desertification, shrub encroachment and dryland development issues as factors of change requiring increased understanding and management. We also review recent technical advances in the quantitative assessment of human versus climate change related drivers of desertification, evapotranspiration partitioning using field deployable stable water isotope systems and the remote sensing of key ecohydrological processes. These technological advances provide new tools that assist in addressing major critical issues in dryland ecohydrology under climate change

  10. The Student-Centered Classroom Made Real: Transforming Student Presentations in an Advanced Course on Technical German

    ERIC Educational Resources Information Center

    Rarick, Damon O.

    2010-01-01

    This article describes how the author has successfully combined polling with more traditional instructional strategies to enhance student presentation skills in an advanced course teaching technical German. By helping students select and prepare topics, anticipate questions and engage the audience, instructors can eliminate some of the root causes…

  11. Advanced algorithms for the identification of mixtures using condensed-phase FT-IR spectroscopy

    NASA Astrophysics Data System (ADS)

    Arnó, Josep; Andersson, Greger; Levy, Dustin; Tomczyk, Carol; Zou, Peng; Zuidema, Eric

    2011-06-01

    FT-IR spectroscopy is the technology of choice to identify solid and liquid phase unknown samples. Advances in instrument portability have made possible the use of FT-IR spectroscopy in emergency response and military field applications. The samples collected in those harsh environments are rarely pure and typically contain multiple chemical species in water, sand, or inorganic matrices. In such critical applications, it is also desired that in addition to broad chemical identification, the user is warned immediately if the sample contains a threat or target class material (i.e. biological, narcotic, explosive). The next generation HazMatID 360 combines the ruggedized design and functionality of the current HazMatID with advanced mixture analysis algorithms. The advanced FT-IR instrument allows effective chemical assessment of samples that may contain one or more interfering materials like water or dirt. The algorithm was the result of years of cumulative experience based on thousands of real-life spectra sent to our ReachBack spectral analysis service by customers in the field. The HazMatID 360 combines mixture analysis with threat detection and chemical hazard classification capabilities to provide, in record time, crucial information to the user. This paper will provide an overview of the software and algorithm enhancements, in addition to examples of improved performance in mixture identification.

  12. Hybrid intravascular imaging: recent advances, technical considerations, and current applications in the study of plaque pathophysiology.

    PubMed

    Bourantas, Christos V; Jaffer, Farouc A; Gijsen, Frank J; van Soest, Gijs; Madden, Sean P; Courtney, Brian K; Fard, Ali M; Tenekecioglu, Erhan; Zeng, Yaping; van der Steen, Antonius F W; Emelianov, Stanislav; Muller, James; Stone, Peter H; Marcu, Laura; Tearney, Guillermo J; Serruys, Patrick W

    2017-02-07

    Cumulative evidence from histology-based studies demonstrate that the currently available intravascular imaging techniques have fundamental limitations that do not allow complete and detailed evaluation of plaque morphology and pathobiology, limiting the ability to accurately identify high-risk plaques. To overcome these drawbacks, new efforts are developing for data fusion methodologies and the design of hybrid, dual-probe catheters to enable accurate assessment of plaque characteristics, and reliable identification of high-risk lesions. Today several dual-probe catheters have been introduced including combined near infrared spectroscopy-intravascular ultrasound (NIRS-IVUS), that is already commercially available, IVUS-optical coherence tomography (OCT), the OCT-NIRS, the OCT-near infrared fluorescence (NIRF) molecular imaging, IVUS-NIRF, IVUS intravascular photoacoustic imaging and combined fluorescence lifetime-IVUS imaging. These multimodal approaches appear able to overcome limitations of standalone imaging and provide comprehensive visualization of plaque composition and plaque biology. The aim of this review article is to summarize the advances in hybrid intravascular imaging, discuss the technical challenges that should be addressed in order to have a use in the clinical arena, and present the evidence from their first applications aiming to highlight their potential value in the study of atherosclerosis. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2016. For permissions please email: journals.permissions@oup.com.

  13. Identification and microbial production of a terpene-based advanced biofuel

    PubMed Central

    Peralta-Yahya, Pamela P.; Ouellet, Mario; Chan, Rossana; Mukhopadhyay, Aindrila; Keasling, Jay D.; Lee, Taek Soon

    2011-01-01

    Rising petroleum costs, trade imbalances and environmental concerns have stimulated efforts to advance the microbial production of fuels from lignocellulosic biomass. Here we identify a novel biosynthetic alternative to D2 diesel fuel, bisabolane, and engineer microbial platforms for the production of its immediate precursor, bisabolene. First, we identify bisabolane as an alternative to D2 diesel by measuring the fuel properties of chemically hydrogenated commercial bisabolene. Then, via a combination of enzyme screening and metabolic engineering, we obtain a more than tenfold increase in bisabolene titers in Escherichia coli to >900 mg l−1. We produce bisabolene in Saccharomyces cerevisiae (>900 mg l−1), a widely used platform for the production of ethanol. Finally, we chemically hydrogenate biosynthetic bisabolene into bisabolane. This work presents a framework for the identification of novel terpene-based advanced biofuels and the rapid engineering of microbial farnesyl diphosphate-overproducing platforms for the production of biofuels. PMID:21952217

  14. Tribal Colleges and Universities/American Indian Research and Education Initiatives Advanced Manufacturing Technical Assistance Project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Atcitty, Stanley

    The overall goal of this project is to establish a network of TCUs with essential advanced manufacturing (AM) facilities, associated training and education programs, and private sector and federal agency partnerships to both prepare an American Indian AM workforce and create economic and employment opportunities within Tribal communities through design, manufacturing, and marketing of high quality products. Some examples of high quality products involve next generation grid components such as mechanical energy storage, cabling for distribution of energy, and electrochemical energy storage enclosures. Sandia National Laboratories (Sandia) is tasked to provide technical advising, planning, and academic program development support formore » the TCU/American Indian Higher Education Consortium (AIHEC) Advanced Manufacturing Project. The TCUs include Bay Mills Community College (BMCC), Cankdeska Cikana Community College (CCCC), Navajo Technical University (NTU), Southwestern Indian Polytechnic Institute (SIPI), and Salish Kooteani College. AIHEC and Sandia, with collaboration from SIPI, will be establishing an 8-week summer institute on the SIPI campus during the summer of 2017. Up to 20 students from TCUs are anticipated to take part in the summer program. The goal of the program is to bring AM science, technology, engineering, and mathematics (STEM) awareness and opportunities for the American Indian students. Prior to the summer institute, Sandia will be providing reviews on curriculum plans at the each of the TCUs to ensure the content is consistent with current AM design and engineering practice. In addition, Sandia will provide technical assistance to each of the TCUs in regards to their current AM activities.« less

  15. Sensor-Only System Identification for Structural Health Monitoring of Advanced Aircraft

    NASA Technical Reports Server (NTRS)

    Kukreja, Sunil L.; Bernstein, Dennis S.

    2012-01-01

    Environmental conditions, cyclic loading, and aging contribute to structural wear and degradation, and thus potentially catastrophic events. The challenge of health monitoring technology is to determine incipient changes accurately and efficiently. This project addresses this challenge by developing health monitoring techniques that depend only on sensor measurements. Since actively controlled excitation is not needed, sensor-to-sensor identification (S2SID) provides an in-flight diagnostic tool that exploits ambient excitation to provide advance warning of significant changes. S2SID can subsequently be followed up by ground testing to localize and quantify structural changes. The conceptual foundation of S2SID is the notion of a pseudo-transfer function, where one sensor is viewed as the pseudo-input and another is viewed as the pseudo-output, is approach is less restrictive than transmissibility identification and operational modal analysis since no assumption is made about the locations of the sensors relative to the excitation.

  16. Fieldcrest Cannon, Inc. Advanced Technical Preparation. Statistical Process Control (SPC). Safety Section: Modules 1-3. Instructor Book.

    ERIC Educational Resources Information Center

    Averitt, Sallie D.

    These three modules, which were developed for use by instructors in a manufacturing firm's advanced technical preparation program, contain the materials required to present the safety section of the plant's adult-oriented, job-specific competency-based training program. The 3 modules contain 12 lessons on the following topics: lockout/tagout…

  17. Fieldcrest Cannon, Inc. Advanced Technical Preparation. Statistical Process Control (SPC). PRE-SPC 11: SPC & Graphs. Instructor Book.

    ERIC Educational Resources Information Center

    Averitt, Sallie D.

    This instructor guide, which was developed for use in a manufacturing firm's advanced technical preparation program, contains the materials required to present a learning module that is designed to prepare trainees for the program's statistical process control module by improving their basic math skills in working with line graphs and teaching…

  18. Atmospheric Reanalyses-Recent Progress and Prospects for the Future. A Report from a Technical Workshop, April 2010. Volume 29

    NASA Technical Reports Server (NTRS)

    Rienecker, Michele M.; Dee, Dick; Woollen, Jack; Compo, Gilbert P.; Onogi, Kazutoshi; Gelaro, Ron; Bosilovich, Michael G.; daSilva, Arlindo; Pawson, Steven; Schubert, Siegfried; hide

    2012-01-01

    In April 2010, developers representing each of the major reanalysis centers met at Goddard Space Flight Center to discuss technical issues - system advances and lessons learned - associated with recent and ongoing atmospheric reanalyses and plans for the future. The meeting included overviews of each center s development efforts, a discussion of the issues in observations, models and data assimilation, and, finally, identification of priorities for future directions and potential areas of collaboration. This report summarizes the deliberations and recommendations from the meeting as well as some advances since the workshop.

  19. Drawing on Technical Writing Scholarship for the Teaching of Writing to Advanced ESL Students--A Writing Tutorial

    ERIC Educational Resources Information Center

    Zielinska, Dorota

    2003-01-01

    The article outlines the technical writing tutorial (TWT) that preceded an advanced ESL writing course for students of English Philology at the Jagiellonian University. Having assessed the English skills of those students at the end of the semester, we found a statistically significant increase in the performance of the students who had taken the…

  20. 9 CFR 351.17 - Identification required.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Transportation and Exportation of Certified Technical Animal Fat § 351.17 Identification required. Certified technical animal fats... certified plants shall be accompanied by MP Form 85 (Declaration to Accompany Technical Animal Fats Between...

  1. 9 CFR 351.17 - Identification required.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Transportation and Exportation of Certified Technical Animal Fat § 351.17 Identification required. Certified technical animal fats... certified plants shall be accompanied by MP Form 85 (Declaration to Accompany Technical Animal Fats Between...

  2. 9 CFR 351.17 - Identification required.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Transportation and Exportation of Certified Technical Animal Fat § 351.17 Identification required. Certified technical animal fats... certified plants shall be accompanied by MP Form 85 (Declaration to Accompany Technical Animal Fats Between...

  3. 9 CFR 351.17 - Identification required.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Transportation and Exportation of Certified Technical Animal Fat § 351.17 Identification required. Certified technical animal fats... certified plants shall be accompanied by MP Form 85 (Declaration to Accompany Technical Animal Fats Between...

  4. 9 CFR 351.17 - Identification required.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Transportation and Exportation of Certified Technical Animal Fat § 351.17 Identification required. Certified technical animal fats... certified plants shall be accompanied by MP Form 85 (Declaration to Accompany Technical Animal Fats Between...

  5. Identification of MAPK Substrates Using Quantitative Phosphoproteomics.

    PubMed

    Zhang, Tong; Schneider, Jacqueline D; Zhu, Ning; Chen, Sixue

    2017-01-01

    Activation of mitogen-activated protein kinases (MAPKs) under diverse biotic and abiotic factors and identification of an array of downstream MAPK target proteins are hot topics in plant signal transduction. Through interactions with a plethora of substrate proteins, MAPK cascades regulate many physiological processes in the course of plant growth, development, and response to environmental factors. Identification and quantification of potential MAPK substrates are essential, but have been technically challenging. With the recent advancement in phosphoproteomics, here we describe a method that couples metal dioxide for phosphopeptide enrichment with tandem mass tags (TMT) mass spectrometry (MS) for large-scale MAPK substrate identification and quantification. We have applied this method to a transient expression system carrying a wild type (WT) and a constitutive active (CA) version of a MAPK. This combination of genetically engineered MAPKs and phosphoproteomics provides a high-throughput, unbiased analysis of MAPK-triggered phosphorylation changes on the proteome scale. Therefore, it is a robust method for identifying potential MAPK substrates and should be applicable in the study of other kinase cascades in plants as well as in other organisms.

  6. Recovery Act. Advanced Load Identification and Management for Buildings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yang, Yi; Casey, Patrick; Du, Liang

    2014-02-12

    solutions, in particular, advanced power strips (APSs) was studied. The project evaluated the market potential for Smart Power Strips (SPSs) with load identification and the likely impact of a load identification feature on APS adoption and effectiveness. The project also identified other success factors required for widespread APS adoption and market acceptance. Even though the developed technology is applicable for both residential and commercial buildings, this project is focused on effective plug-in load control and management for commercial buildings, accomplished through effective load identification. The project has completed Smart Receptacle (SR) prototype development with integration of Load ID, Control/Management, WiFi communication, and Web Service. Twenty SR units were built, tested, and demonstrated in the Eaton lab; eight SR units were tested in the National Renewable Energy Lab (NREL) for one-month of field testing. Load ID algorithm testing for extended load sets was conducted within the Eaton facility and at local university campuses. This report is to summarize the major achievements, activities, and outcomes under the execution of the project.« less

  7. DOE Advanced Scientific Computing Advisory Committee (ASCAC) Subcommittee Report on Scientific and Technical Information

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hey, Tony; Agarwal, Deborah; Borgman, Christine

    The Advanced Scientific Computing Advisory Committee (ASCAC) was charged to form a standing subcommittee to review the Department of Energy’s Office of Scientific and Technical Information (OSTI) and to begin by assessing the quality and effectiveness of OSTI’s recent and current products and services and to comment on its mission and future directions in the rapidly changing environment for scientific publication and data. The Committee met with OSTI staff and reviewed available products, services and other materials. This report summaries their initial findings and recommendations.

  8. Technical guidelines for the implementation of the Advanced National Seismic System

    USGS Publications Warehouse

    Committee, ANSS Technical Integration

    2002-01-01

    The Advanced National Seismic System (ANSS) is a major national initiative led by the US Geological Survey that serves the needs of the earthquake monitoring, engineering, and research communities as well as national, state, and local governments, emergency response organizations, and the general public. Legislation authorizing the ANSS was passed in 2000, and low levels of funding for planning and initial purchases of new seismic instrumentation have been appropriated beginning in FY2000. When fully operational, the ANSS will be an advanced monitoring system (modern digital seismographs and accelerographs, communications networks, data collection and processing centers, and well-trained personnel) distributed across the United States that operates with high performance standards, gathers critical technical data, and effectively provides timely and reliable earthquake products, information, and services to meet the Nation’s needs. The ANSS will automatically broadcast timely and authoritative products describing the occurrence of earthquakes, earthquake source properties, the distribution of ground shaking, and, where feasible, broadcast early warnings and alerts for the onset of strong ground shaking. Most importantly, the ANSS will provide earthquake data, derived products, and information to the public, emergency responders, officials, engineers, educators, researchers, and other ANSS partners rapidly and in forms that are useful for their needs.

  9. Forensic interlaboratory evaluation of the ForFLUID kit for vaginal fluids identification.

    PubMed

    Giampaoli, Saverio; Alessandrini, Federica; Berti, Andrea; Ripani, Luigi; Choi, Ajin; Crab, Roselien; De Vittori, Elisabetta; Egyed, Balazs; Haas, Cordula; Lee, Hwan Young; Korabecná, Marie; Noel, Fabrice; Podini, Daniele; Tagliabracci, Adriano; Valentini, Alessio; Romano Spica, Vincenzo

    2014-01-01

    Identification of vaginal fluids is an important step in the process of sexual assaults confirmation. Advances in both microbiology and molecular biology defined technical approaches allowing the discrimination of body fluids. These protocols are based on the identification of specific bacterial communities by microfloraDNA (mfDNA) amplification. A multiplex real time-PCR assay (ForFLUID kit) has been developed for identifying biological fluids and for discrimination among vaginal, oral and fecal samples. In order to test its efficacy and reliability of the assay in the identification of vaginal fluids, an interlaboratory evaluation has been performed on homogeneous vaginal swabs. All the involved laboratories were able to correctly recognize all the vaginal swabs, and no false positives were identified when the assay was applied on non-vaginal samples. The assay represents an useful molecular tool that can be easily adopted by forensic geneticists involved in vaginal fluid identification. Copyright © 2013 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  10. Advances in molecular identification, taxonomy, genetic variation and diagnosis of Toxocara spp.

    PubMed

    Chen, Jia; Zhou, Dong-Hui; Nisbet, Alasdair J; Xu, Min-Jun; Huang, Si-Yang; Li, Ming-Wei; Wang, Chun-Ren; Zhu, Xing-Quan

    2012-10-01

    The genus Toxocara contains parasitic nematodes of human and animal health significance, such as Toxocara canis, Toxocara cati and Toxocara vitulorum. T. canis and T. cati are among the most prevalent parasites of dogs and cats with a worldwide distribution. Human infection with T. canis and T. cati, which can cause a number of clinical manifestations such as visceral larva migrans (VLMs), ocular larva migrans (OLMs), eosinophilic meningoencephalitis (EME), covert toxocariasis (CT) and neurotoxocariasis, is considered the most prevalent neglected helminthiasis in industrialized countries. The accurate identification Toxocara spp. and their unequivocal differentiation from each other and from other ascaridoid nematodes causing VLMs and OLMs has important implications for studying their taxonomy, epidemiology, population genetics, diagnosis and control. Due to the limitations of traditional (morphological) approaches for identification and diagnosis of Toxocara spp., PCR-based techniques utilizing a range of genetic markers in the nuclear and mitochondrial genomes have been developed as useful alternative approaches because of their high sensitivity, specificity, rapidity and utility. In this article, we summarize the current state of knowledge and advances in molecular identification, taxonomy, genetic variation and diagnosis of Toxocara spp. with prospects for further studies. Copyright © 2012 Elsevier B.V. All rights reserved.

  11. Advances in Dendrobium molecular research: Applications in genetic variation, identification and breeding.

    PubMed

    Teixeira da Silva, Jaime A; Jin, Xiaohua; Dobránszki, Judit; Lu, Jiangjie; Wang, Huizhong; Zotz, Gerhard; Cardoso, Jean Carlos; Zeng, Songjun

    2016-02-01

    Orchids of the genus Dendrobium are of great economic importance in global horticultural trade and in Asian traditional medicine. For both areas, research yielding solid information on taxonomy, phylogeny, and breeding of this genus are essential. Traditional morphological and cytological characterization are used in combination with molecular results in classification and identification. Markers may be useful when used alone but are not always reliable in identification. The number of species studied and identified by molecular markers is small at present. Conventional breeding methods are time-consuming and laborious. In the past two decades, promising advances have been made in taxonomy, phylogeny and breeding of Dendrobium species due to the intensive use of molecular markers. In this review, we focus on the main molecular techniques used in 121 published studies and discuss their importance and possibilities in speeding up the breeding of new cultivars and hybrids. Copyright © 2015 Elsevier Inc. All rights reserved.

  12. Technical advances power neuroscience

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barinaga, M.

    New techniques are helping researchers study the development of nerve cells in cell cultures and in vivo. These new methods are offering insights into the brain that were not available even a couple of years ago. Among the new advances discussed are imaging technology for evaluating the thinking human brain. One area in which researchers have made recent progress is the quest for ways to create immortal cell lines from specific types of nerve cells. Other projects using genetically engineered retroviruses and tumor-inducing genes, as well as gene regulation are discussed. Recent advances in neuroscience techniques apply not only tomore » neurons, but also to whole brains as well. One example is a high-resulution electroencephalogram (EEG). Although the EEG cannot pin down the actual sites of activity as precisely as static brain imaging methods, it complements them with real-time recording that can keep up with the very rapid pace of brain activity.« less

  13. Plant Aquaporins: Genome-Wide Identification, Transcriptomics, Proteomics, and Advanced Analytical Tools.

    PubMed

    Deshmukh, Rupesh K; Sonah, Humira; Bélanger, Richard R

    2016-01-01

    Aquaporins (AQPs) are channel-forming integral membrane proteins that facilitate the movement of water and many other small molecules. Compared to animals, plants contain a much higher number of AQPs in their genome. Homology-based identification of AQPs in sequenced species is feasible because of the high level of conservation of protein sequences across plant species. Genome-wide characterization of AQPs has highlighted several important aspects such as distribution, genetic organization, evolution and conserved features governing solute specificity. From a functional point of view, the understanding of AQP transport system has expanded rapidly with the help of transcriptomics and proteomics data. The efficient analysis of enormous amounts of data generated through omic scale studies has been facilitated through computational advancements. Prediction of protein tertiary structures, pore architecture, cavities, phosphorylation sites, heterodimerization, and co-expression networks has become more sophisticated and accurate with increasing computational tools and pipelines. However, the effectiveness of computational approaches is based on the understanding of physiological and biochemical properties, transport kinetics, solute specificity, molecular interactions, sequence variations, phylogeny and evolution of aquaporins. For this purpose, tools like Xenopus oocyte assays, yeast expression systems, artificial proteoliposomes, and lipid membranes have been efficiently exploited to study the many facets that influence solute transport by AQPs. In the present review, we discuss genome-wide identification of AQPs in plants in relation with recent advancements in analytical tools, and their availability and technological challenges as they apply to AQPs. An exhaustive review of omics resources available for AQP research is also provided in order to optimize their efficient utilization. Finally, a detailed catalog of computational tools and analytical pipelines is

  14. Plant Aquaporins: Genome-Wide Identification, Transcriptomics, Proteomics, and Advanced Analytical Tools

    PubMed Central

    Deshmukh, Rupesh K.; Sonah, Humira; Bélanger, Richard R.

    2016-01-01

    Aquaporins (AQPs) are channel-forming integral membrane proteins that facilitate the movement of water and many other small molecules. Compared to animals, plants contain a much higher number of AQPs in their genome. Homology-based identification of AQPs in sequenced species is feasible because of the high level of conservation of protein sequences across plant species. Genome-wide characterization of AQPs has highlighted several important aspects such as distribution, genetic organization, evolution and conserved features governing solute specificity. From a functional point of view, the understanding of AQP transport system has expanded rapidly with the help of transcriptomics and proteomics data. The efficient analysis of enormous amounts of data generated through omic scale studies has been facilitated through computational advancements. Prediction of protein tertiary structures, pore architecture, cavities, phosphorylation sites, heterodimerization, and co-expression networks has become more sophisticated and accurate with increasing computational tools and pipelines. However, the effectiveness of computational approaches is based on the understanding of physiological and biochemical properties, transport kinetics, solute specificity, molecular interactions, sequence variations, phylogeny and evolution of aquaporins. For this purpose, tools like Xenopus oocyte assays, yeast expression systems, artificial proteoliposomes, and lipid membranes have been efficiently exploited to study the many facets that influence solute transport by AQPs. In the present review, we discuss genome-wide identification of AQPs in plants in relation with recent advancements in analytical tools, and their availability and technological challenges as they apply to AQPs. An exhaustive review of omics resources available for AQP research is also provided in order to optimize their efficient utilization. Finally, a detailed catalog of computational tools and analytical pipelines is

  15. Semiannual Technical Summary, 1 October 1990 - 31 March 1991 (Royal Norwegian Council for Scientific and Industrial Research)

    DTIC Science & Technology

    1991-05-01

    Ronal Njorwegian Council !,r ScrerithC arid Industrial RuseIarch R A YI~L ~ AD-A242 758 NORSAR Scientific Report No . 2-90/91 Semiannual Technical...Authorization T/9141/B/PKP ARPA Order No . 4138 AMD # 16 Program Code No . OF10 Name of Contractor Royal Norwegian Council for Scientific and Industrial ...PROCUREMENT INSTRUMENT IDENTIFICATION NUMBER ORGANIZATION Defense Advanced -- "’able) Contract No . F08606-89-C-0005 Pae~h rjsct A ..... 8c. ADDRESS (Ci-tytate

  16. Technical Readiness and Gaps Analysis of Commercial Optical Materials and Measurement Systems for Advanced Small Modular Reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Anheier, Norman C.; Suter, Jonathan D.; Qiao, Hong

    2013-08-06

    This report intends to support Department of Energy’s Office of Nuclear Energy (DOE-NE) Nuclear Energy Research and Development Roadmap and industry stakeholders by evaluating optical-based instrumentation and control (I&C) concepts for advanced small modular reactor (AdvSMR) applications. These advanced designs will require innovative thinking in terms of engineering approaches, materials integration, and I&C concepts to realize their eventual viability and deployability. The primary goals of this report include: 1. Establish preliminary I&C needs, performance requirements, and possible gaps for AdvSMR designs based on best available published design data. 2. Document commercial off-the-shelf (COTS) optical sensors, components, and materials in termsmore » of their technical readiness to support essential AdvSMR in-vessel I&C systems. 3. Identify technology gaps by comparing the in-vessel monitoring requirements and environmental constraints to COTS optical sensor and materials performance specifications. 4. Outline a future research, development, and demonstration (RD&D) program plan that addresses these gaps and develops optical-based I&C systems that enhance the viability of future AdvSMR designs. The development of clean, affordable, safe, and proliferation-resistant nuclear power is a key goal that is documented in the Nuclear Energy Research and Development Roadmap. This roadmap outlines RD&D activities intended to overcome technical, economic, and other barriers, which currently limit advances in nuclear energy. These activities will ensure that nuclear energy remains a viable component to this nation’s energy security.« less

  17. Testing isotopic labeling with [¹³C₆]glucose as a method of advanced glycation sites identification.

    PubMed

    Kielmas, Martyna; Kijewska, Monika; Stefanowicz, Piotr; Szewczuk, Zbigniew

    2012-12-01

    The Maillard reaction occurring between reducing sugars and reactive amino groups of biomolecules leads to the formation of a heterogeneous mixture of compounds: early, intermediate, and advanced glycation end products (AGEs). These compounds could be markers of certain diseases and of the premature aging process. Detection of Amadori products can be performed by various methods, including MS/MS techniques and affinity chromatography on immobilized boronic acid. However, the diversity of the structures of AGEs makes detection of these compounds more difficult. The aim of this study was to test a new method of AGE identification based on isotope (13)C labeling. The model protein (hen egg lysozyme) was modified with an equimolar mixture of [(12)C(6)]glucose and [(13)C(6)]glucose and then subjected to reduction of the disulfide bridges followed by tryptic hydrolysis. The digest obtained was analyzed by LC-MS. The glycation products were identified on the basis of characteristic isotopic patterns resulting from the use of isotopically labeled glucose. This method allowed identification of 38 early Maillard reaction products and five different structures of the end glycation products. This isotopic labeling technique combined with LC-MS is a sensitive method for identification of advanced glycation end products even if their chemical structure is unknown. Copyright © 2012 Elsevier Inc. All rights reserved.

  18. Identification of non-technical skills from the resilience engineering perspective: a case study of an electricity distributor.

    PubMed

    Wachs, Priscila; Righi, Angela Weber; Saurin, Tarcisio Abreu

    2012-01-01

    Training in non-technical skills (NTS) does not usually question the design of the work system, and thus focuses narrowly on workers as the unit of analysis. This study discusses how the identification of NTS, a major step for developing an NTS training program, might be re-interpreted from the perspective of resilience engineering (RE). This discussion is based on a case study of identifying NTS for electricians who perform emergency maintenance activities in an electricity distribution power line. The results of the case study point out that four data analysis procedures might operationalize the RE perspective: (a) identifying factors that make the work difficult and which could be integrated into NTS training scenarios; (b) identifying recommendations for re-designing the system, in order either to reduce or eliminate the need for NTS; (c) classifying the NTS into pragmatic categories, which are meaningful for workers; and (d) regarding the identification of NTS as an opportunity to give visibility to adaptations carried out by workers.

  19. Ethics in Technical Communication. The Allyn & Bacon Series in Technical Communication.

    ERIC Educational Resources Information Center

    Dombrowski, Paul

    Arguing that ethics is an important part of technical communication, this book discusses ethics in the broad sense including not only the act of communication but also where technical information came from and how it likely will be used. It is intended for advanced undergraduate and graduate audiences, and assumes some familiarity with technical…

  20. Technical advance: identification of plant actin-binding proteins by F-actin affinity chromatography

    NASA Technical Reports Server (NTRS)

    Hu, S.; Brady, S. R.; Kovar, D. R.; Staiger, C. J.; Clark, G. B.; Roux, S. J.; Muday, G. K.

    2000-01-01

    Proteins that interact with the actin cytoskeleton often modulate the dynamics or organization of the cytoskeleton or use the cytoskeleton to control their localization. In plants, very few actin-binding proteins have been identified and most are thought to modulate cytoskeleton function. To identify actin-binding proteins that are unique to plants, the development of new biochemical procedures will be critical. Affinity columns using actin monomers (globular actin, G-actin) or actin filaments (filamentous actin, F-actin) have been used to identify actin-binding proteins from a wide variety of organisms. Monomeric actin from zucchini (Cucurbita pepo L.) hypocotyl tissue was purified to electrophoretic homogeneity and shown to be native and competent for polymerization to actin filaments. G-actin, F-actin and bovine serum albumin affinity columns were prepared and used to separate samples enriched in either soluble or membrane-associated actin-binding proteins. Extracts of soluble actin-binding proteins yield distinct patterns when eluted from the G-actin and F-actin columns, respectively, leading to the identification of a putative F-actin-binding protein of approximately 40 kDa. When plasma membrane-associated proteins were applied to these columns, two abundant polypeptides eluted selectively from the F-actin column and cross-reacted with antiserum against pea annexins. Additionally, a protein that binds auxin transport inhibitors, the naphthylphthalamic acid binding protein, which has been previously suggested to associate with the actin cytoskeleton, was eluted in a single peak from the F-actin column. These experiments provide a new approach that may help to identify novel actin-binding proteins from plants.

  1. Technical advance: identification of plant actin-binding proteins by F-actin affinity chromatography.

    PubMed

    Hu, S; Brady, S R; Kovar, D R; Staiger, C J; Clark, G B; Roux, S J; Muday, G K

    2000-10-01

    Proteins that interact with the actin cytoskeleton often modulate the dynamics or organization of the cytoskeleton or use the cytoskeleton to control their localization. In plants, very few actin-binding proteins have been identified and most are thought to modulate cytoskeleton function. To identify actin-binding proteins that are unique to plants, the development of new biochemical procedures will be critical. Affinity columns using actin monomers (globular actin, G-actin) or actin filaments (filamentous actin, F-actin) have been used to identify actin-binding proteins from a wide variety of organisms. Monomeric actin from zucchini (Cucurbita pepo L.) hypocotyl tissue was purified to electrophoretic homogeneity and shown to be native and competent for polymerization to actin filaments. G-actin, F-actin and bovine serum albumin affinity columns were prepared and used to separate samples enriched in either soluble or membrane-associated actin-binding proteins. Extracts of soluble actin-binding proteins yield distinct patterns when eluted from the G-actin and F-actin columns, respectively, leading to the identification of a putative F-actin-binding protein of approximately 40 kDa. When plasma membrane-associated proteins were applied to these columns, two abundant polypeptides eluted selectively from the F-actin column and cross-reacted with antiserum against pea annexins. Additionally, a protein that binds auxin transport inhibitors, the naphthylphthalamic acid binding protein, which has been previously suggested to associate with the actin cytoskeleton, was eluted in a single peak from the F-actin column. These experiments provide a new approach that may help to identify novel actin-binding proteins from plants.

  2. Background Perchlorate Source Identification Technical Guidance

    DTIC Science & Technology

    2013-12-01

    Sciences Branch (Code 71752) of the Advanced Systems and Applied Sciences Division (Code 71700), Space and Naval Warfare Systems Center (SSC Pacific), San...Head Advanced Systems & Applied Sciences Division iii EXECUTIVE SUMMARY The objective of this document is to outline the approach, tools, and...Helium HMX Octahydro-1,3,5,7-Tetranitro-1,3,5,7- Tetrazocine IR Installation Restoration IRIS Integrated Risk Information System IR-MS Isotope-Ratio

  3. Advancements in robust algorithm formulation for speaker identification of whispered speech

    NASA Astrophysics Data System (ADS)

    Fan, Xing

    for the transformation estimation in order to generate the pseudo whispered features. Both of the above two systems demonstrate a significant improvement over the baseline system on the evaluation data. This dissertation has therefore contributed to providing a scientific understanding of the differences between whispered and neutral speech as well as improved front-end processing and modeling method for speaker identification of whispered speech. Such advancements will ultimately contribute to improve the robustness of speech processing systems.

  4. Advances in identification and validation of protein targets of natural products without chemical modification.

    PubMed

    Chang, J; Kim, Y; Kwon, H J

    2016-05-04

    Covering: up to February 2016Identification of the target proteins of natural products is pivotal to understanding the mechanisms of action to develop natural products for use as molecular probes and potential therapeutic drugs. Affinity chromatography of immobilized natural products has been conventionally used to identify target proteins, and has yielded good results. However, this method has limitations, in that labeling or tagging for immobilization and affinity purification often result in reduced or altered activity of the natural product. New strategies have recently been developed and applied to identify the target proteins of natural products and synthetic small molecules without chemical modification of the natural product. These direct and indirect methods for target identification of label-free natural products include drug affinity responsive target stability (DARTS), stability of proteins from rates of oxidation (SPROX), cellular thermal shift assay (CETSA), thermal proteome profiling (TPP), and bioinformatics-based analysis of connectivity. This review focuses on and reports case studies of the latest advances in target protein identification methods for label-free natural products. The integration of newly developed technologies will provide new insights and highlight the value of natural products for use as biological probes and new drug candidates.

  5. The impact of transition training on adapting to Technically Advanced Aircraft at regional airlines: Perceptions of pilots and instructor pilots

    NASA Astrophysics Data System (ADS)

    di Renzo, John Carl, Jr.

    Scope and method of study. The purpose of this study was to test a hypothesis about pilot and instructor pilot perceptions of how effectively pilots learn and use new technology, found in Technically Advanced Aircraft (TAA), given initial type of instrumentation training. New aviation technologies such as Glass Cockpits in technically advanced aircraft are complex and can be difficult to learn and use. The research questions focused on the type of initial instrumentation training to determine the differences among pilots trained using various types of instrumentation ranging from aircraft equipped with traditional analog instrumentation to aircraft equipped with glass cockpits. A convenience sample of Pilots in Training (PT) and Instructor Pilots (IP) was selected from a regional airline. The research design used a mixed methodology. Pilots in training completed a thirty-two question quantitative questionnaire and instructor pilots completed a five question qualitative questionnaire. Findings and conclusions. This investigation failed to disprove the null hypothesis. The type of instrumentation training has no significant effect on newly trained regional airline pilot perceived ability to adapt to advanced technology cockpits. Therefore, no evidence exists from this investigation to support the early introduction and training of TAA. While the results of this investigation were surprising, they are nonetheless, instructive. Even though it would seem that there would be a relationship between exposure to and use of technically advanced instrumentation, apparently there was no perceived relationship for this group of airline transport pilots. However, a point of interest is that these pilots were almost evenly divided in their opinion of whether or not their previous training had prepared them for transition to TAA. The majority also believed that the type of initial instrumentation training received does make a difference when transitioning to TAA. Pilots believed

  6. Identification of technical item flaws leads to improvement of the quality of single best Multiple Choice Questions.

    PubMed

    Fayyaz Khan, Humaira; Farooq Danish, Khalid; Saeed Awan, Azra; Anwar, Masood

    2013-05-01

    The purpose of the study was to identify technical item flaws in the multiple choice questions submitted for the final exams for the years 2009, 2010 and 2011. This descriptive analytical study was carried out in Islamic International Medical College (IIMC). The Data was collected from the MCQ's submitted by the faculty for the final exams for the year 2009, 2010 and 2011. The data was compiled and evaluated by a three member assessment committee. The data was analyzed for frequency and percentages the categorical data was analyzed by chi-square test. Overall percentage of flawed item was 67% for the year 2009 of which 21% were for testwiseness and 40% were for irrelevant difficulty. In year 2010 the total item flaws were 36% and 11% testwiseness and 22% were for irrelevant difficulty. The year 2011 data showed decreased overall flaws of 21%. The flaws of testwisness were 7%, irrelevant difficulty were 11%. Technical item flaws are frequently encountered during MCQ construction, and the identification of flaws leads to improved quality of the single best MCQ's.

  7. 44 CFR 65.3 - Requirement to submit new technical data.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... available, a community shall notify the Administrator of the changes by submitting technical or scientific... IDENTIFICATION AND MAPPING OF SPECIAL HAZARD AREAS § 65.3 Requirement to submit new technical data. A community's...

  8. Technical analysis of US Army Weapons Systems and related advanced technologies of military interest. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1991-06-14

    This report summarizes the activities and accomplishments of an US Army technology security project designed to identify and develop effective policy guidelines for militarily critical technologies in specific Army systems and in broad generic technology areas of military interest, Individual systems analyses are documented in separate Weapons Systems Technical Assessments (WSTAs) and the general generic technology areas are evaluated in the Advanced Technology Assessment Reports (ATARs), However, specific details of these assessments are not addressed here, only recommendations regarding aspects of the defined approach, methodology, and format are provided and discussed.

  9. Technical Basis for Physical Fidelity of NRC Control Room Training Simulators for Advanced Reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Minsk, Brian S.; Branch, Kristi M.; Bates, Edward K.

    2009-10-09

    The objective of this study is to determine how simulator physical fidelity influences the effectiveness of training the regulatory personnel responsible for examination and oversight of operating personnel and inspection of technical systems at nuclear power reactors. It seeks to contribute to the U.S. Nuclear Regulatory Commission’s (NRC’s) understanding of the physical fidelity requirements of training simulators. The goal of the study is to provide an analytic framework, data, and analyses that inform NRC decisions about the physical fidelity requirements of the simulators it will need to train its staff for assignment at advanced reactors. These staff are expected tomore » come from increasingly diverse educational and experiential backgrounds.« less

  10. Recent Advances in Mass Spectrometry for the Identification of Neuro-chemicals and their Metabolites in Biofluids.

    PubMed

    Kailasa, Suresh Kumar; Wu, Hui-Fen

    2013-07-01

    Recently, mass spectrometric related techniques have been widely applied for the identification and quantification of neurochemicals and their metabolites in biofluids. This article presents an overview of mass spectrometric techniques applied in the detection of neurological substances and their metabolites from biological samples. In addition, the advances of chromatographic methods (LC, GC and CE) coupled with mass spectrometric techniques for analysis of neurochemicals in pharmaceutical and biological samples are also discussed.

  11. Shuttle ku-band communications/radar technical concepts

    NASA Technical Reports Server (NTRS)

    Griffin, J. W.; Kelley, J. S.; Steiner, A. W.; Vang, H. A.; Zrubek, W. E.; Huth, G. K.

    1985-01-01

    Technical data on the Shuttle Orbiter K sub u-band communications/radar system are presented. The more challenging aspects of the system design and development are emphasized. The technical problems encountered and the advancements made in solving them are discussed. The radar functions are presented first. Requirements and design/implementation approaches are discussed. Advanced features are explained, including Doppler measurement, frequency diversity, multiple pulse repetition frequencies and pulse widths, and multiple modes. The communications functions that are presented include advances made because of the requirements for multiple communications modes. Spread spectrum, quadrature phase shift keying (QPSK), variable bit rates, and other advanced techniques are discussed. Performance results and conclusions reached are outlined.

  12. [Recent advances in metabonomics].

    PubMed

    Xu, Guo-Wang; Lu, Xin; Yang, Sheng-Li

    2007-12-01

    Metabonomics (or metabolomics) aims at the comprehensive and quantitative analysis of the wide arrays of metabolites in biological samples. Metabonomics has been labeled as one of the new" -omics" joining genomics, transcriptomics, and proteomics as a science employed toward the understanding of global systems biology. It has been widely applied in many research areas including drug toxicology, biomarker discovery, functional genomics, and molecular pathology etc. The comprehensive analysis of the metabonome is particularly challenging due to the diverse chemical natures of metabolites. Metabonomics investigations require special approaches for sample preparation, data-rich analytical chemical measurements, and information mining. The outputs from a metabonomics study allow sample classification, biomarker discovery, and interpretation of the reasons for classification information. This review focuses on the currently new advances in various technical platforms of metabonomics and its applications in drug discovery and development, disease biomarker identification, plant and microbe related fields.

  13. 9 CFR 351.18 - Official identifications; unauthorized use.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AND VOLUNTARY INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT... § 351.3 and the term “Certified Technical Animal Fat” are official identifications for purposes of the... any designation as certified technical animal fat shall be filled in whole or in part, except with...

  14. 9 CFR 351.18 - Official identifications; unauthorized use.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AND VOLUNTARY INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT... § 351.3 and the term “Certified Technical Animal Fat” are official identifications for purposes of the... any designation as certified technical animal fat shall be filled in whole or in part, except with...

  15. 9 CFR 351.18 - Official identifications; unauthorized use.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AND VOLUNTARY INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT... § 351.3 and the term “Certified Technical Animal Fat” are official identifications for purposes of the... any designation as certified technical animal fat shall be filled in whole or in part, except with...

  16. 9 CFR 351.18 - Official identifications; unauthorized use.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AND VOLUNTARY INSPECTION AND CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT... § 351.3 and the term “Certified Technical Animal Fat” are official identifications for purposes of the... any designation as certified technical animal fat shall be filled in whole or in part, except with...

  17. Technical and Energy Performance of an Advanced, Aqueous Ammonia-Based CO2 Capture Technology for a 500 MW Coal-Fired Power Station.

    PubMed

    Li, Kangkang; Yu, Hai; Feron, Paul; Tade, Moses; Wardhaugh, Leigh

    2015-08-18

    Using a rate-based model, we assessed the technical feasibility and energy performance of an advanced aqueous-ammonia-based postcombustion capture process integrated with a coal-fired power station. The capture process consists of three identical process trains in parallel, each containing a CO2 capture unit, an NH3 recycling unit, a water separation unit, and a CO2 compressor. A sensitivity study of important parameters, such as NH3 concentration, lean CO2 loading, and stripper pressure, was performed to minimize the energy consumption involved in the CO2 capture process. Process modifications of the rich-split process and the interheating process were investigated to further reduce the solvent regeneration energy. The integrated capture system was then evaluated in terms of the mass balance and the energy consumption of each unit. The results show that our advanced ammonia process is technically feasible and energy-competitive, with a low net power-plant efficiency penalty of 7.7%.

  18. Advanced coal conversion process demonstration. Technical progress report for the period July 1, 1995--September 30, 1995

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1997-05-01

    This report describes the technical progress made on the Advanced Coal Conversion Process (ACCP) Demonstration Project from July 1, 1995 through September 30, 1995. The ACCP Demonstration Project is a US Department of Energy (DOE) Clean Coal Technology Project. This project demonstrates an advanced, thermal, coal upgrading process, coupled with physical cleaning techniques, that is designed to upgrade high-moisture, low-rank coals to a high-quality, low-sulfur fuel, registered as the SynCoal process. The coal is processed through three stages (two heating stages followed by an inert cooling stage) of vibrating fluidized bed reactors that remove chemically bound water, carboxyl groups, andmore » volatile sulfur compounds. After thermal upgrading, the cola is put through a deep-bed stratifier cleaning process to separate the pyrite-rich ash from the coal.« less

  19. The potential for advanced computerized aids for comprehensible writing of technical documents

    NASA Astrophysics Data System (ADS)

    Kieras, D. E.

    1985-01-01

    It is widely agreed that technical documents for equipment are poorly written and hard to comprehend. This has been a long-standing problem because the information-processing demands of editing and revision are so high that many comprehensibility problems go undetected. However, many of these problems can be detected by computerized systems that scan a document and point out where the writing can be improved. Existing systems of this type are based on conventional writing customs, rather than on the research literature on comprehension, and give poor advice or miss important problems. They also do not process the input document to any depth. An approach to advanced writing aids is described; such a system would base its criticisms on what is known about the cognition psychology of comprehension, and would make use of techniques from artificial intelligence for processing the language. Some examples of the relevant research results are presented, and a demonstration system of this type is briefly described.

  20. Second NASA Technical Interchange Meeting (TIM): Advanced Technology Lifecycle Analysis System (ATLAS) Technology Tool Box (TTB)

    NASA Technical Reports Server (NTRS)

    ONeil, D. A.; Mankins, J. C.; Christensen, C. B.; Gresham, E. C.

    2005-01-01

    The Advanced Technology Lifecycle Analysis System (ATLAS), a spreadsheet analysis tool suite, applies parametric equations for sizing and lifecycle cost estimation. Performance, operation, and programmatic data used by the equations come from a Technology Tool Box (TTB) database. In this second TTB Technical Interchange Meeting (TIM), technologists, system model developers, and architecture analysts discussed methods for modeling technology decisions in spreadsheet models, identified specific technology parameters, and defined detailed development requirements. This Conference Publication captures the consensus of the discussions and provides narrative explanations of the tool suite, the database, and applications of ATLAS within NASA s changing environment.

  1. Technical Advances in Intracellular Detection Using Immuno-Gold Particles: Simple Cryofixation with Metal Contact Quick Freezing.

    PubMed

    Song, Chihong; Lee, Ju Huck; Jun, Sangmi; Chung, Jeong Min; Hyun, Jaekyung; Jung, Hyun Suk

    2016-05-01

    The preparation of biological specimens using cryofixation techniques ensures excellent visibility of intracellular structures and preserves the antigenic sites of subcellular molecules. Hence, cryofixation is an effective method of preparing samples for analyses using antibodies conjugated to gold nanoparticles that are designed to detect the localization of specific target molecules within cells. However, cryofixation cannot be utilized easily because it requires expensive equipment and skilled technologists, resulting in a high level of expense for researchers. Here, we describe a simple technical approach to cryofixation that uses metal contact quick freezing followed by a modified freeze substitution technique and immuno-gold labeling electron microscopy. Micrograph images of cells prepared using this modified cryofixation method demonstrated its superiority over chemical fixation for high contrast visualization of the morphologies of cellular components and preservation of antigenicity for immuno-gold labeling. This report provides valuable technical information related to the advancement of metal contact quick freezing techniques, which can be used to visualize biomedical events of interest in an easy, simple, and rapid manner.

  2. Isolation of n-decyl-alpha(1-->6) isomaltoside from a technical APG mixture and its identification by the parallel use of LC-MS and NMR spectroscopy

    PubMed

    Billian; Hock; Doetzer; Stan; Dreher

    2000-10-15

    The identification of n-decyl alpha(1-->6)isomaltoside as a main component of technical alkyl polyglucoside (APG) mixtures by the parallel use of liquid chromatography-mass spectrometry (LC-MS) and nuclear magnetic resonance (NMR) spectroscopy is described. Following enrichment on a styrene-divinylbenzene-based solid-phase extraction material, unknown components were separated by reversed-phase liquid chromatography (LC). Chemical characterization was achieved by both mass spectrometry and NMR spectroscopy. It is demonstrated that the combination of LC-MS with various NMR techniques is very suitable for stereochemical assignment of unknown components in technical APG mixtures.

  3. NASA University Research Centers Technical Advances in Aeronautics, Space Sciences and Technology, Earth Systems Sciences, Global Hydrology, and Education. Volumes 2 and 3

    NASA Technical Reports Server (NTRS)

    Coleman, Tommy L. (Editor); White, Bettie (Editor); Goodman, Steven (Editor); Sakimoto, P. (Editor); Randolph, Lynwood (Editor); Rickman, Doug (Editor)

    1998-01-01

    This volume chronicles the proceedings of the 1998 NASA University Research Centers Technical Conference (URC-TC '98), held on February 22-25, 1998, in Huntsville, Alabama. The University Research Centers (URCS) are multidisciplinary research units established by NASA at 11 Historically Black Colleges or Universities (HBCU's) and 3 Other Minority Universities (OMU's) to conduct research work in areas of interest to NASA. The URC Technical Conferences bring together the faculty members and students from the URC's with representatives from other universities, NASA, and the aerospace industry to discuss recent advances in their fields.

  4. Method of identification of patent trends based on descriptions of technical functions

    NASA Astrophysics Data System (ADS)

    Korobkin, D. M.; Fomenkov, S. A.; Golovanchikov, A. B.

    2018-05-01

    The use of the global patent space to determine the scientific and technological priorities for the technical systems development (identifying patent trends) allows one to forecast the direction of the technical systems development and, accordingly, select patents of priority technical subjects as a source for updating the technical functions database and physical effects database. The authors propose an original method that uses as trend terms not individual unigrams or n-gram (usually for existing methods and systems), but structured descriptions of technical functions in the form “Subject-Action-Object” (SAO), which in the authors’ opinion are the basis of the invention.

  5. Advanced Combat Helmet Technical Assessment

    DTIC Science & Technology

    2013-05-29

    Lastly, we assessed the participation of various stakeholders and industry experts such as active ACH manufacturers and test facilities. Findings... industrially accepted American National Standards Institute (ANSI Z1.4-2008, Sampling Visit us on the web at www.dodig.mil Results in Brief Advanced...statistically principled approach and the lot acceptance test protocol adopts a widely established and industrially accepted sampling procedure. We

  6. Naval Training Device Center Index of Technical Reports.

    ERIC Educational Resources Information Center

    Walker, Lemuel E.

    Published Naval Training Device Center technical reports and some technical notes (those available through the Defense Documentation Center-DDC) which have resulted from basic research, exploratory development, and advanced development type projects are listed. The reports are indexed by technical note number, by title, and by contractor code. The…

  7. Advanced Manufacturing Research | NREL

    Science.gov Websites

    engineering research in advanced manufacturing is focused on the identification and development of advanced materials and advanced processes that drive the impact of new energy technologies. Our world-class strategies, and policy evaluation. We partner with industry to bridge innovation gaps in advanced

  8. Technical Needs for Prototypic Prognostic Technique Demonstration for Advanced Small Modular Reactor Passive Components

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meyer, Ryan M.; Coble, Jamie B.; Hirt, Evelyn H.

    2013-05-17

    This report identifies a number of requirements for prognostics health management of passive systems in AdvSMRs, documents technical gaps in establishing a prototypical prognostic methodology for this purpose, and describes a preliminary research plan for addressing these technical gaps. AdvSMRs span multiple concepts; therefore a technology- and design-neutral approach is taken, with the focus being on characteristics that are likely to be common to all or several AdvSMR concepts. An evaluation of available literature is used to identify proposed concepts for AdvSMRs along with likely operational characteristics. Available operating experience of advanced reactors is used in identifying passive components thatmore » may be subject to degradation, materials likely to be used for these components, and potential modes of degradation of these components. This information helps in assessing measurement needs for PHM systems, as well as defining functional requirements of PHM systems. An assessment of current state-of-the-art approaches to measurements, sensors and instrumentation, diagnostics and prognostics is also documented. This state-of-the-art evaluation, combined with the requirements, may be used to identify technical gaps and research needs in the development, evaluation, and deployment of PHM systems for AdvSMRs. A preliminary research plan to address high-priority research needs for the deployment of PHM systems to AdvSMRs is described, with the objective being the demonstration of prototypic prognostics technology for passive components in AdvSMRs. Greater efficiency in achieving this objective can be gained through judicious selection of materials and degradation modes that are relevant to proposed AdvSMR concepts, and for which significant knowledge already exists. These selections were made based on multiple constraints including the analysis performed in this document, ready access to laboratory-scale facilities for materials testing and measurement

  9. Identification of mine rescue equipment reduction gears technical condition

    NASA Astrophysics Data System (ADS)

    Gerike, B. L.; Klishin, V. I.; Kuzin, E. G.

    2017-09-01

    The article presents the reasons for adopting intelligent service of mine belt conveyer drives concerning evaluation of their technical condition based on the diagnostic techniques instead of regular preventative maintenance. The article reveals the diagnostic results of belt conveyer drive reduction gears condition taking into account the parameters of lubricating oil, vibration and temperature. Usage of a complex approach to evaluate technical conditions allows reliability of the forecast to be improved, which makes it possible not only to prevent accidental breakdowns and eliminate unscheduled downtime, but also to bring sufficient economic benefits through reduction of the term and scope of work during overhauls.

  10. 44 CFR 65.3 - Requirement to submit new technical data.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... technical data. 65.3 Section 65.3 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY... IDENTIFICATION AND MAPPING OF SPECIAL HAZARD AREAS § 65.3 Requirement to submit new technical data. A community's base flood elevations may increase or decrease resulting from physical changes affecting flooding...

  11. Stakeholder identification of advanced technology opportunities at international ports of entry

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Parker, S.K.; Icerman, L.

    As part of the Advanced Technologies for International and Intermodal Ports of Entry (ATIPE) Project, a diverse group of stakeholders was engaged to help identify problems experienced at inland international border crossings, particularly those at the US-Mexican border. The fundamental issue at international ports of entry is reducing transit time through the required documentation and inspection processes. Examples of other issues or problems, typically manifested as time delays at border crossings, repeatedly mentioned by stakeholders include: (1) lack of document standardization; (2) failure to standardize inspection processes; (3) inadequate information and communications systems; (4) manual fee and tariff collection; (5)more » inconsistency of processes and procedures; and (6) suboptimal cooperation among governmental agencies. Most of these issues can be addressed to some extent by the development of advanced technologies with the objective of allowing ports of entry to become more efficient while being more effective. Three categories of technologies were unambiguously of high priority to port of entry stakeholders: (1) automated documentation; (2) systems integration; and (3) vehicle and cargo tracking. Together, these technologies represent many of the technical components necessary for pre-clearance of freight approaching international ports of entry. Integration of vehicle and cargo tracking systems with port of entry information and communications systems, as well as existing industry legacy systems, should further enable border crossings to be accomplished consistently with optimal processing times.« less

  12. Technical Support Document: Development of the Advanced Energy Design Guide for K-12 Schools--30% Energy Savings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pless, S.; Torcellini, P.; Long, N.

    2007-09-01

    This Technical Support Document describes the process and methodology for the development of the Advanced Energy Design Guide for K-12 School Buildings (K-12 AEDG), a design guidance document intended to provide recommendations for achieving 30% energy savings in K-12 Schools over levels contained in ANSI/ASHRAE/IESNA Standard 90.1-1999, Energy Standard for Buildings Except Low-Rise Residential Buildings. The 30% energy savings target is the first step toward achieving net-zero energy schools; schools that, on an annual basis, draw from outside sources less or equal energy than they generate on site from renewable energy sources.

  13. A citrus waste-based biorefinery as a source of renewable energy: technical advances and analysis of engineering challenges.

    PubMed

    Rivas-Cantu, Raul C; Jones, Kim D; Mills, Patrick L

    2013-04-01

    An assessment of recent technical advances on pretreatment processes and its effects on enzymatic hydrolysis as the main steps of a proposed citrus processing waste (CPW) biorefinery is presented. Engineering challenges and relevant gaps in scientific and technical information for reliable design, modeling and scale up of a CPW biorefinery are also discussed. Some integrated physico-chemical pretreatments are proposed for testing for CPW, including high speed knife-grinding and simultaneous caustic addition. These new proposed processes and the effect of parameters such as particle size, surface area and morphology, pore volume and chemical composition of the diverse fractions resulting from pretreatment and enzymatic hydrolysis need to be evaluated and compared for pretreated and untreated samples of grapefruit processing waste. This assessment suggests the potential for filling the data gaps, and preliminary results demonstrate that the reduction of particle size and the increased surface area for the CPW will result in higher reaction rates and monosaccharide yields for the pretreated waste material.

  14. 48 CFR 252.204-7012 - Safeguarding of unclassified controlled technical information.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    .... Cyber incident means actions taken through the use of computer networks that result in an actual or... printed within an information system. Technical information means technical data or computer software, as..., catalog-item identifications, data sets, studies and analyses and related information, and computer...

  15. Environmentally Responsible Aviation (ERA) Project - N+2 Advanced Vehicle Concepts Study and Conceptual Design of Subscale Test Vehicle (STV) Final Report

    NASA Technical Reports Server (NTRS)

    Bonet, John T.; Schellenger, Harvey G.; Rawdon, Blaine K.; Elmer, Kevin R.; Wakayama, Sean R.; Brown, Derrell L.; Guo, Yueping

    2011-01-01

    NASA has set demanding goals for technology developments to meet national needs to improve fuel efficiency concurrent with improving the environment to enable air transportation growth. A figure shows NASA's subsonic transport system metrics. The results of Boeing ERA N+2 Advanced Vehicle Concept Study show that the Blended Wing Body (BWB) vehicle, with ultra high bypass propulsion systems have the potential to meet the combined NASA ERA N+2 goals. This study had 3 main activities. 1) The development of an advanced vehicle concepts that can meet the NASA system level metrics. 2) Identification of key enabling technologies and the development of technology roadmaps and maturation plans. 3) The development of a subscale test vehicle that can demonstrate and mature the key enabling technologies needed to meet the NASA system level metrics. Technology maturation plans are presented and include key performance parameters and technical performance measures. The plans describe the risks that will be reduced with technology development and the expected progression of technical maturity.

  16. A Theory of the Function of Technical Writing.

    ERIC Educational Resources Information Center

    Ross, Donald, Jr.

    1981-01-01

    Advances the theory that technical writing functions as a replacement for memory--an information storage receptacle. Lists the formal and stylistic features implied by such a theory. Considers the future development of technical writing within the context of this theory. (RL)

  17. Technical Assistance | NREL

    Science.gov Websites

    Multi-Wind Heat Smart Grid Project. Advancing Energy Solutions in Alaska NREL provides analysis mission to transfer knowledge and innovation to solve the nation's energy challenges. The goal of this transportation energy efficiency and reduce transportation energy costs State Technical Assistance-solar market

  18. Technical Support Document: The Development of the Advanced Energy Design Guide for Highway Lodging Buildings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jiang, Wei; Jarnagin, Ronald E.; Gowri, Krishnan

    2008-09-30

    This Technical Support Document (TSD) describes the process and methodology for development of the Advanced Energy Design Guide for Highway Lodgings (AEDG-HL or the Guide), a design guidance document intended to provide recommendations for achieving 30% energy savings in highway lodging properties over levels contained in ANSI/ASHRAE/IESNA Standard 90.1-1999, Energy Standard for Buildings Except Low-Rise Residential Buildings. The AEDG-HL is the fifth in a series of guides being developed by a partnership of organizations, including the American Society of Heating, Refrigerating and Air-Conditioning Engineers, Inc. (ASHRAE), the American Institute of Architects (AIA), the Illuminating Engineering Society of North America (IESNA),more » the United States Green Buildings Council (USGBC), and the U.S. Department of Energy (DOE).« less

  19. CCD detector development projects by the Beamline Technical Support Group at the Advanced Photon Source

    NASA Astrophysics Data System (ADS)

    Lee, John H.; Fernandez, Patricia; Madden, Tim; Molitsky, Michael; Weizeorick, John

    2007-11-01

    This paper will describe two ongoing detector projects being developed by the Beamline Technical Support Group at the Advanced Photon Source (APS) at Argonne National Laboratory (ANL). The first project is the design and construction of two detectors: a single-CCD system and a two-by-two Mosaic CCD camera for Small-Angle X-ray Scattering (SAXS). Both of these systems utilize the Kodak KAF-4320E CCD coupled to fiber optic tapers, custom mechanical hardware, electronics, and software developed at ANL. The second project is a Fast-CCD (FCCD) detector being developed in a collaboration between ANL and Lawrence Berkeley National Laboratory (LBNL). This detector will use ANL-designed readout electronics and a custom LBNL-designed CCD, with 480×480 pixels and 96 outputs, giving very fast readout.

  20. Epigenome-wide association studies for cancer biomarker discovery in circulating cell-free DNA: technical advances and challenges.

    PubMed

    Tanić, Miljana; Beck, Stephan

    2017-02-01

    Since introducing the concept of epigenome-wide association studies (EWAS) in 2011, there has been a vast increase in the number of published EWAS studies in common diseases, including in cancer. These studies have increased our understanding of epigenetic events underlying carcinogenesis and have enabled the discovery of cancer-specific methylation biomarkers. In this mini-review, we have focused on the state of the art in EWAS applied to cell-free circulating DNA for epigenetic biomarker discovery in cancer and discussed associated technical advances and challenges, and our expectations for the future of the field. Copyright © 2017 The Author(s). Published by Elsevier Ltd.. All rights reserved.

  1. 44 CFR 65.4 - Right to submit new technical data.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Right to submit new technical... IDENTIFICATION AND MAPPING OF SPECIAL HAZARD AREAS § 65.4 Right to submit new technical data. (a) A community has..., other than those initiatedby FEMA, must be made in writing by the Chief Executive Officer of the...

  2. Analysis of plant germline development by high-throughput RNA profiling: technical advances and new insights.

    PubMed

    Schmidt, Anja; Schmid, Marc W; Grossniklaus, Ueli

    2012-04-01

    Reproduction is a crucial step in the life cycle of plants. The male and female germline lineages develop in the reproductive organs of the flower, which in higher plants are the anthers and ovules, respectively. Development of the germline lineage initiates from a dedicated sporophytic cell that undergoes meiosis to form spores that subsequently give rise to the gametophytes through mitotic cell divisions. The mature male and female gametophytes harbour the male (sperm cells) and female gametes (egg and central cell), respectively. Those unite during double fertilization to initiate embryo and endosperm development in sexually reproducing higher plants. While cytological changes involved in development of the germline lineages have been well characterized in a number of species, investigation of the transcriptional basis underlying their development and the specification of the gametes proved challenging. This is largely due to the inaccessibility of the cells constituting the germline lineages, which are enclosed by sporophytic tissues. Only recently, these technical limitations could be overcome by combining new methods to isolate the relevant cells with powerful transcriptional profiling methods, such as microarrays or high-throughput sequencing of RNA. This review focuses on these technical advances and the new insights gained from them concerning the transcriptional basis and molecular mechanisms underlying germline development. © 2012 The Authors. The Plant Journal © 2012 Blackwell Publishing Ltd.

  3. Advanced Launch System advanced development oxidizer turbopump program: Technical implementation plan

    NASA Technical Reports Server (NTRS)

    Ferlita, F.

    1989-01-01

    The Advanced Launch Systems (ALS) Advanced Development Oxidizer Turbopump Program has designed, fabricated and demonstrated a low cost, highly reliable oxidizer turbopump for the Space Transportation Engine that minimizes the recurring cost for the ALS engines. Pratt and Whitney's (P and W's) plan for integrating the analyses, testing, fabrication, and other program efforts is addressed. This plan offers a comprehensive description of the total effort required to design, fabricate, and test the ALS oxidizer turbopump. The proposed ALS oxidizer turbopump reduces turbopump costs over current designs by taking advantage of design simplicity and state-of-the-art materials and producibility features without compromising system reliability. This is accomplished by selecting turbopump operating conditions that are within known successful operating regions and by using proven manufacturing techniques.

  4. Recent progress toward the identification of anti-viral immune mechanisms in decapod crustaceans.

    PubMed

    Hauton, Chris

    2017-07-01

    The sustainable intensification of crustacean aquaculture, which is dominated by the farming of penaeid shrimp species, continues to be beset by viral disease outbreaks. Despite this, reports exist of differential susceptibility to viral infection between different shrimp species and populations, and between shrimp and other decapod crustaceans. These reports have, in part, provided the motivation to identify key mechanisms of antiviral resistance, or refractivity, in commercially-important species. Within the last decade these studies have created significant advances in our understanding of host virus interactions in decapod models. However, at the same time, the complexity of host virus interactions has presented significant challenges for interpretation of anti-viral immune responses. In this short review, recent progress in our understanding of the complexity of host virus interactions are considered, and challenges to the unequivocal identification of anti-viral immunity are highlighted. Special consideration is given to the advances in understanding being created by the use of RNA interference approaches. Based on the 'state of the art', it is concluded that the identification of effective intervention strategies for application at farm scale currently presents an unrealistic target for the aquaculture industry. Future technical developments necessary to support continued progress are also considered. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Fingerprint identification: advances since the 2009 National Research Council report

    PubMed Central

    Champod, Christophe

    2015-01-01

    This paper will discuss the major developments in the area of fingerprint identification that followed the publication of the National Research Council (NRC, of the US National Academies of Sciences) report in 2009 entitled: Strengthening Forensic Science in the United States: A Path Forward. The report portrayed an image of a field of expertise used for decades without the necessary scientific research-based underpinning. The advances since the report and the needs in selected areas of fingerprinting will be detailed. It includes the measurement of the accuracy, reliability, repeatability and reproducibility of the conclusions offered by fingerprint experts. The paper will also pay attention to the development of statistical models allowing assessment of fingerprint comparisons. As a corollary of these developments, the next challenge is to reconcile a traditional practice dominated by deterministic conclusions with the probabilistic logic of any statistical model. There is a call for greater candour and fingerprint experts will need to communicate differently on the strengths and limitations of their findings. Their testimony will have to go beyond the blunt assertion of the uniqueness of fingerprints or the opinion delivered ispe dixit. PMID:26101284

  6. 48 CFR 1852.245-74 - Identification and marking of Government equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Technical Handbook (NASA-HDBK) 6003, Application of Data Matrix Identification Symbols to Aerospace Parts... Identification Symbols on Aerospace Parts or through the use of commercial marking techniques that: (1) are...

  7. 48 CFR 1852.245-74 - Identification and marking of Government equipment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Technical Handbook (NASA-HDBK) 6003, Application of Data Matrix Identification Symbols to Aerospace Parts... Identification Symbols on Aerospace Parts or through the use of commercial marking techniques that: (1) are...

  8. 48 CFR 1852.245-74 - Identification and marking of Government equipment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Technical Handbook (NASA-HDBK) 6003, Application of Data Matrix Identification Symbols to Aerospace Parts... Identification Symbols on Aerospace Parts or through the use of commercial marking techniques that: (1) are...

  9. 48 CFR 1852.245-74 - Identification and marking of Government equipment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Technical Handbook (NASA-HDBK) 6003, Application of Data Matrix Identification Symbols to Aerospace Parts... Identification Symbols on Aerospace Parts or through the use of commercial marking techniques that: (1) are...

  10. Technical Workshop: Advanced Helicopter Cockpit Design

    NASA Technical Reports Server (NTRS)

    Hemingway, J. C. (Editor); Callas, G. P. (Editor)

    1984-01-01

    Information processing demands on both civilian and military aircrews have increased enormously as rotorcraft have come to be used for adverse weather, day/night, and remote area missions. Applied psychology, engineering, or operational research for future helicopter cockpit design criteria were identified. Three areas were addressed: (1) operational requirements, (2) advanced avionics, and (3) man-system integration.

  11. ASTM Committee C28: International Standards for Properties and Performance of Advanced Ceramics-Three Decades of High-Quality, Technically-Rigorous Normalization

    NASA Technical Reports Server (NTRS)

    Jenkins, Michael G.; Salem, Jonathan A.

    2016-01-01

    Physical and mechanical properties and performance of advanced ceramics and glasses are difficult to measure correctly without the proper techniques. For over three decades, ASTM Committee C28 on Advanced Ceramics, has developed high-quality, technically-rigorous, full-consensus standards (e.g., test methods, practices, guides, terminology) to measure properties and performance of monolithic and composite ceramics that may be applied to glasses in some cases. These standards contain testing particulars for many mechanical, physical, thermal, properties and performance of these materials. As a result these standards are used to generate accurate, reliable, repeatable and complete data. Within Committee C28, users, producers, researchers, designers, academicians, etc. have written, continually updated, and validated through round-robin test programs, 50 standards since the Committee's founding in 1986. This paper provides a detailed retrospective of the 30 years of ASTM Committee C28 including a graphical pictogram listing of C28 standards along with examples of the tangible benefits of standards for advanced ceramics to demonstrate their practical applications.

  12. Biometrics, identification and surveillance.

    PubMed

    Lyon, David

    2008-11-01

    Governing by identity describes the emerging regime of a globalizing, mobile world. Governance depends on identification but identification increasingly depends on biometrics. This 'solution' to difficulties of verification is described and some technical weaknesses are discussed. The role of biometrics in classification systems is also considered and is shown to contain possible prejudice in relation to racialized criteria of identity. Lastly, the culture of biometric identification is shown to be limited to abstract data, artificially separated from the lived experience of the body including the orientation to others. It is proposed that creators of national ID systems in particular address these crucial deficiencies in their attempt to provide new modes of verification.

  13. APTS : advanced public transportation systems program : technical assistance brief

    DOT National Transportation Integrated Search

    1993-01-01

    Advanced Public Transportation Systems, or APTS, are advanced navigation and communication technologies applied to all aspects of public transportation system operations. APTS provides the technology for transportation agencies to make timely transit...

  14. The Development of Nanotechnologies and Advanced Materials Industry in Science and Entrepreneurship: Socioeconomic and Technical Indicators. A Case Study of Latvia (Part One)

    NASA Astrophysics Data System (ADS)

    Geipele, I.; Geipele, S.; Staube, T.; Ciemleja, G.; Zeltins, N.

    2016-08-01

    The present scientific paper is the first part of two publications, where the authors obtain results from the scientific research presented in a series of works on the development of the nanotechnologies and advanced materials industry in science and entrepreneurship in Latvia. The study has a focus on finding proper socioeconomic and technical indicators. It provides resume on a scope of the study. The paper contains the developed structure of engineering economic indicator system, determined groups of indicators for assessment of the development of nanotechnologies and advanced materials industry in Latvia and results of the evaluation of the obtained statistics on the economic indicators.

  15. Drainage identification analysis and mapping, phase 2 : technical brief.

    DOT National Transportation Integrated Search

    2017-01-01

    This research studied, tested and rectified the compatibility issue related to the recent upgrades of : NJDOT vendor inspection software, and uploaded all collected data to make Drainage Identification : Analysis and Mapping System (DIAMS) current an...

  16. Technical and economic evaluation of advanced air cargo system concepts

    NASA Technical Reports Server (NTRS)

    Whitehead, A. H., Jr.

    1977-01-01

    The paper reviews NASA air cargo market studies, reports on NASA and NASA-sponsored studies of advanced freighter concepts, and identifies the opportunities for the application of advanced technology. The air cargo market is studied to evaluate the timing for, and the potential market response to, advanced technology aircraft. The degree of elasticity in future air freight markets is also being investigated, since the demand for a new aircraft is most favorable in a price-sensitive environment. Aircraft design studies are considered with attention to mission and design requirements, incorporation of advanced technologies in transport aircraft, new cargo aircraft concepts, advanced freighter evaluation, and civil-military design commonality.

  17. Technical Challenges for a Comprehensive Test Ban: A historical perspective to frame the future (Invited)

    NASA Astrophysics Data System (ADS)

    Wallace, T. C.

    2013-12-01

    In the summer of 1958 scientists from the Soviet block and the US allies met in Geneva to discuss what it would take to monitor a forerunner to a Comprehensive Test Ban Treaty at the 'Conference of Experts to Study the Possibility of Detecting Violations of a Possible Agreement on Suspension of Nuclear Tests'. Although armed with a limited resume of observations, the conference recommended a multi-phenomenology approach (air sampling, acoustics, seismic and electromagnetic) deployed it a network of 170 sites scattered across the Northern Hemisphere, and hypothesized a detection threshold of 1kt for atmospheric tests and 5kt for underground explosions. The conference recommendations spurred vigorous debate, with strong disagreement with the stated detection hypothesis. Nevertheless, the technical challenges posed lead to a very focused effort to improve facilities, methodologies and, most importantly, research and development on event detection, location and identification. In the ensuing 50 years the various challenges arose and were eventually 'solved'; these included quantifying yield determination to enter a Limited Threshold Test Ban, monitoring broad areas of emerging nuclear nations, and after the mid-1990s lowering the global detection threshold to sub-kiloton levels for underground tests. Today there is both an international monitoring regime (ie, the International Monitoring System, or IMS) and a group of countries that have their own national technical means (NTM). The challenges for the international regime are evolving; the IMS has established itself as a very credible monitoring system, but the demand of a CTBT to detect and identify a 'nuclear test' of diminished size (zero yield) poses new technical hurdles. These include signal processing and understanding limits of resolution, location accuracy, integration of heterogeneous data, and accurately characterizing anomalous events. It is possible to extrapolate past technical advances to predict what

  18. Emphasis: Technical Education. Conference Report (St. Louis, Mo., May 12-14, 1966).

    ERIC Educational Resources Information Center

    American Association of Junior Colleges, Washington, DC.

    The purpose of this conference was to bring expertise in the field of technical education to bear upon the identification and resolution of problems inhibiting the expansion of programs at the junior college level. Sixty-four participants were involved. The conference focused upon the relationships of technical education to: society, college…

  19. W(h)ither human cardiac and body magnetic resonance at ultrahigh fields? technical advances, practical considerations, applications, and clinical opportunities.

    PubMed

    Niendorf, Thoralf; Paul, Katharina; Oezerdem, Celal; Graessl, Andreas; Klix, Sabrina; Huelnhagen, Till; Hezel, Fabian; Rieger, Jan; Waiczies, Helmar; Frahm, Jens; Nagel, Armin M; Oberacker, Eva; Winter, Lukas

    2016-09-01

    The objective of this study was to document and review advances and groundbreaking progress in cardiac and body MR at ultrahigh fields (UHF, B0 ≥ 7.0 T) with the goal to attract talent, clinical adopters, collaborations and resources to the biomedical and diagnostic imaging communities. This review surveys traits, advantages and challenges of cardiac and body MR at 7.0 T. The considerations run the gamut from technical advances to clinical opportunities. Key concepts, emerging technologies, practical considerations, frontier applications and future directions of UHF body and cardiac MR are provided. Examples of UHF cardiac and body imaging strategies are demonstrated. Their added value over the kindred counterparts at lower fields is explored along with an outline of research promises. The achievements of cardiac and body UHF-MR are powerful motivators and enablers, since extra speed, signal and imaging capabilities may be invested to overcome the fundamental constraints that continue to hamper traditional cardiac and body MR applications. If practical obstacles, concomitant physics effects and technical impediments can be overcome in equal measure, sophisticated cardiac and body UHF-MR will help to open the door to new MRI and MRS approaches for basic research and clinical science, with the lessons learned at 7.0 T being transferred into broad clinical use including diagnostics and therapy guiding at lower fields. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.

  20. Making Advanced Computer Science Topics More Accessible through Interactive Technologies

    ERIC Educational Resources Information Center

    Shao, Kun; Maher, Peter

    2012-01-01

    Purpose: Teaching advanced technical concepts in a computer science program to students of different technical backgrounds presents many challenges. The purpose of this paper is to present a detailed experimental pedagogy in teaching advanced computer science topics, such as computer networking, telecommunications and data structures using…

  1. Atmospheric Research 2011 Technical Highlights

    NASA Technical Reports Server (NTRS)

    2012-01-01

    The 2011 Technical Highlights describes the efforts of all members of Atmospheric Research. Their dedication to advancing Earth Science through conducting research, developing and running models, designing instruments, managing projects, running field campaigns, and numerous other activities, is highlighted in this report.

  2. [Advanced Composites Technology Initiatives

    NASA Technical Reports Server (NTRS)

    Julian, Mark R.

    2002-01-01

    This final report closes out the W02 NASA Grant #NCC5-646. The FY02 grant for advanced technology initiatives through the Advanced Composites Technology Institute in Bridgeport, WV, at the Robert C. Byrd Institute (RCBI) Bridgeport Manufacturing Technology Center, is complete; all funding has been expended. RCBI continued to expand access to technology; develop and implement a workforce-training curriculum; improve material development; and provide prototyping and demonstrations of new and advanced composites technologies for West Virginia composites firms. The FY 02 efforts supported workforce development, technical training and the HST development effort of a super-lightweight composite carrier prototype and expanded the existing technical capabilities of the growing aerospace industry across West Virginia to provide additional support for NASA missions. Additionally, the Composites Technology and Training Center was awarded IS0 9001 - 2000 certification and Cleanroom Class 1000 certification during this report period.

  3. Vibrio parahaemolyticus: a review on the pathogenesis, prevalence, and advance molecular identification techniques

    PubMed Central

    Letchumanan, Vengadesh; Chan, Kok-Gan; Lee, Learn-Han

    2014-01-01

    Vibrio parahaemolyticus is a Gram-negative halophilic bacterium that is found in estuarine, marine and coastal environments. V. parahaemolyticus is the leading causal agent of human acute gastroenteritis following the consumption of raw, undercooked, or mishandled marine products. In rare cases, V. parahaemolyticus causes wound infection, ear infection or septicaemia in individuals with pre-existing medical conditions. V. parahaemolyticus has two hemolysins virulence factors that are thermostable direct hemolysin (tdh)-a pore-forming protein that contributes to the invasiveness of the bacterium in humans, and TDH-related hemolysin (trh), which plays a similar role as tdh in the disease pathogenesis. In addition, the bacterium is also encodes for adhesions and type III secretion systems (T3SS1 and T3SS2) to ensure its survival in the environment. This review aims at discussing the V. parahaemolyticus growth and characteristics, pathogenesis, prevalence and advances in molecular identification techniques. PMID:25566219

  4. Stressor Identification Guidance Document

    EPA Science Inventory

    EPA has made availabile the Stressor Identification Guidance Document (EPA 822-B-00-025) published under the authority of Section 304(a)(2) of the Clean Water Act (CWA). This technical guidance doc...

  5. Technical tips and advancements in pediatric minimally invasive surgical training on porcine based simulations.

    PubMed

    Narayanan, Sarath Kumar; Cohen, Ralph Clinton; Shun, Albert

    2014-06-01

    Minimal access techniques have transformed the way pediatric surgery is practiced. Due to various constraints, surgical residency programs have not been able to tutor adequate training skills in the routine setting. The advent of new technology and methods in minimally invasive surgery (MIS), has similarly contributed to the need for systematic skills' training in a safe, simulated environment. To enable the training of the proper technique among pediatric surgery trainees, we have advanced a porcine non-survival model for endoscopic surgery. The technical advancements over the past 3 years and a subjective validation of the porcine model from 114 participating trainees using a standard questionnaire and a 5-point Likert scale have been described here. Mean attitude scores and analysis of variance (ANOVA) were used for statistical analysis of the data. Almost all trainees agreed or strongly agreed that the animal-based model was appropriate (98.35%) and also acknowledged that such workshops provided adequate practical experience before attempting on human subjects (96.6%). Mean attitude score for respondents was 19.08 (SD 3.4, range 4-20). Attitude scores showed no statistical association with years of experience or the level of seniority, indicating a positive attitude among all groups of respondents. Structured porcine-based MIS training should be an integral part of skill acquisition for pediatric surgery trainees and the experience gained can be transferred into clinical practice. We advocate that laparoscopic training should begin in a controlled workshop setting before procedures are attempted on human patients.

  6. Advanced imaging in acute stroke management-Part I: Computed tomographic.

    PubMed

    Saini, Monica; Butcher, Ken

    2009-01-01

    Neuroimaging is fundamental to stroke diagnosis and management. Non-contrast computed tomography (NCCT) has been the primary imaging modality utilized for this purpose for almost four decades. Although NCCT does permit identification of intracranial hemorrhage and parenchymal ischemic changes, insights into blood vessel patency and cerebral perfusion are limited. Advances in reperfusion strategies have made identification of potentially salvageable brain tissue a more practical concern. Advances in CT technology now permit identification of acute and chronic arterial lesions, as well as cerebral blood flow deficits. This review outlines principles of advanced CT image acquisition and its utility in acute stroke management.

  7. Technical Support Document: Development of the Advanced Energy Design Guide for Large Hospitals - 50% Energy Savings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bonnema, E.; Leach, M.; Pless, S.

    2013-06-01

    This Technical Support Document describes the process and methodology for the development of the Advanced Energy Design Guide for Large Hospitals: Achieving 50% Energy Savings Toward a Net Zero Energy Building (AEDG-LH) ASHRAE et al. (2011b). The AEDG-LH is intended to provide recommendations for achieving 50% whole-building energy savings in large hospitals over levels achieved by following Standard 90.1-2004. The AEDG-LH was created for a 'standard' mid- to large-size hospital, typically at least 100,000 ft2, but the strategies apply to all sizes and classifications of new construction hospital buildings. Its primary focus is new construction, but recommendations may be applicablemore » to facilities undergoing total renovation, and in part to many other hospital renovation, addition, remodeling, and modernization projects (including changes to one or more systems in existing buildings).« less

  8. Conversion of paper-based technical manuals to interactive electronic technical manuals

    NASA Astrophysics Data System (ADS)

    Kuo, Mu-Hsing

    1999-12-01

    An IETM is intended to be the functional equivalent of a paper-based Technical Manual (TM), and in most cases a total replacement for paper manual. In this paper, we will describe some of document image understanding technologies applied to the conversion of paper-based TMs to IETMs. Using these advanced technologies allow us to convert paper-based TMs to class 1/2 IETMs. However, these were not sufficient for an automated integrated logistics support system in the ROC Department of Defense. An advanced IETM system is therefore required. Such class 4/5 like IETM system could provide intelligent display of information and other user applications such as diagnostics, intelligent design and manufacturing, or computer-managed training. The author has developed some of the advanced functions, and examples will be shown to demonstrate the new aspect of IETMs.

  9. The Chinese Visible Human (CVH) datasets incorporate technical and imaging advances on earlier digital humans

    PubMed Central

    Zhang, Shao-Xiang; Heng, Pheng-Ann; Liu, Zheng-Jin; Tan, Li-Wen; Qiu, Ming-Guo; Li, Qi-Yu; Liao, Rong-Xia; Li, Kai; Cui, Gao-Yu; Guo, Yan-Li; Yang, Xiao-Ping; Liu, Guang-Jiu; Shan, Jing-Lu; Liu, Ji-Jun; Zhang, Wei-Guo; Chen, Xian-Hong; Chen, Jin-Hua; Wang, Jian; Chen, Wei; Lu, Ming; You, Jian; Pang, Xue-Li; Xiao, Hong; Xie, Yong-Ming; Cheng, Jack Chun-Yiu

    2004-01-01

    We report the availability of a digitized Chinese male and a digitzed Chinese female typical of the population and with no obvious abnormalities. The embalming and milling procedures incorporate three technical improvements over earlier digitized cadavers. Vascular perfusion with coloured gelatin was performed to facilitate blood vessel identification. Embalmed cadavers were embedded in gelatin and cryosectioned whole so as to avoid section loss resulting from cutting the body into smaller pieces. Milling performed at −25 °C prevented small structures (e.g. teeth, concha nasalis and articular cartilage) from falling off from the milling surface. The male image set (.tiff images each of 36 Mb) has a section resolution of 3072 × 2048 pixels (∼170 μm, the accompanying magnetic resonance imaging and computer tomography data have a resolution of 512 × 512, i.e. ∼440 μm). The Chinese Visible Human male and female datasets are available at http://www.chinesevisiblehuman.com. (The male is 90.65 Gb and female 131.04 Gb). MPEG videos of direct records of real-time volume rendering are at: http://www.cse.cuhk.edu.hk/~crc PMID:15032906

  10. Center for Advanced Space Propulsion

    NASA Technical Reports Server (NTRS)

    1995-01-01

    The Center for Advanced Space Propulsion (CASP) is part of the University of Tennessee-Calspan Center for Aerospace Research (CAR). It was formed in 1985 to take advantage of the extensive research faculty and staff of the University of Tennessee and Calspan Corporation. It is also one of sixteen NASA sponsored Centers established to facilitate the Commercial Development of Space. Based on investigators' qualifications in propulsion system development, and matching industries' strong intent, the Center focused its efforts in the following technical areas: advanced chemical propulsion, electric propulsion, AI/Expert systems, fluids management in microgravity, and propulsion materials processing. This annual report focuses its discussion in these technical areas.

  11. RNA-seq: technical variability and sampling

    PubMed Central

    2011-01-01

    Background RNA-seq is revolutionizing the way we study transcriptomes. mRNA can be surveyed without prior knowledge of gene transcripts. Alternative splicing of transcript isoforms and the identification of previously unknown exons are being reported. Initial reports of differences in exon usage, and splicing between samples as well as quantitative differences among samples are beginning to surface. Biological variation has been reported to be larger than technical variation. In addition, technical variation has been reported to be in line with expectations due to random sampling. However, strategies for dealing with technical variation will differ depending on the magnitude. The size of technical variance, and the role of sampling are examined in this manuscript. Results In this study three independent Solexa/Illumina experiments containing technical replicates are analyzed. When coverage is low, large disagreements between technical replicates are apparent. Exon detection between technical replicates is highly variable when the coverage is less than 5 reads per nucleotide and estimates of gene expression are more likely to disagree when coverage is low. Although large disagreements in the estimates of expression are observed at all levels of coverage. Conclusions Technical variability is too high to ignore. Technical variability results in inconsistent detection of exons at low levels of coverage. Further, the estimate of the relative abundance of a transcript can substantially disagree, even when coverage levels are high. This may be due to the low sampling fraction and if so, it will persist as an issue needing to be addressed in experimental design even as the next wave of technology produces larger numbers of reads. We provide practical recommendations for dealing with the technical variability, without dramatic cost increases. PMID:21645359

  12. Blurring the Lines: Leveraging Internet Technology for Successful Blending of Secondary/Post-Secondary Technical Education

    ERIC Educational Resources Information Center

    Ryan, Kenneth; Kopischke, Kevin

    2008-01-01

    The Remote Automation Management Platform (RAMP) is a real-time, interactive teaching tool which leverages common off-the-shelf internet technologies to provide high school learners extraordinary access to advanced technical education opportunities. This outreach paradigm is applicable to a broad range of advanced technical skills from automation…

  13. Parameter identification for nonlinear aerodynamic systems

    NASA Technical Reports Server (NTRS)

    Pearson, Allan E.

    1993-01-01

    This final technical report covers a three and one-half year period preceding February 28, 1993 during which support was provided under NASA Grant NAG-1-1065. Following a general description of the system identification problem and a brief survey of methods to attack it, the basic ideas behind the approach taken in this research effort are presented. The results obtained are described with reference to the published work, including the five semiannual progress reports previously submitted and two interim technical reports.

  14. Systematic genomic identification of colorectal cancer genes delineating advanced from early clinical stage and metastasis

    PubMed Central

    2013-01-01

    Background Colorectal cancer is the third leading cause of cancer deaths in the United States. The initial assessment of colorectal cancer involves clinical staging that takes into account the extent of primary tumor invasion, determining the number of lymph nodes with metastatic cancer and the identification of metastatic sites in other organs. Advanced clinical stage indicates metastatic cancer, either in regional lymph nodes or in distant organs. While the genomic and genetic basis of colorectal cancer has been elucidated to some degree, less is known about the identity of specific cancer genes that are associated with advanced clinical stage and metastasis. Methods We compiled multiple genomic data types (mutations, copy number alterations, gene expression and methylation status) as well as clinical meta-data from The Cancer Genome Atlas (TCGA). We used an elastic-net regularized regression method on the combined genomic data to identify genetic aberrations and their associated cancer genes that are indicators of clinical stage. We ranked candidate genes by their regression coefficient and level of support from multiple assay modalities. Results A fit of the elastic-net regularized regression to 197 samples and integrated analysis of four genomic platforms identified the set of top gene predictors of advanced clinical stage, including: WRN, SYK, DDX5 and ADRA2C. These genetic features were identified robustly in bootstrap resampling analysis. Conclusions We conducted an analysis integrating multiple genomic features including mutations, copy number alterations, gene expression and methylation. This integrated approach in which one considers all of these genomic features performs better than any individual genomic assay. We identified multiple genes that robustly delineate advanced clinical stage, suggesting their possible role in colorectal cancer metastatic progression. PMID:24308539

  15. Technical advances in proteomics: new developments in data-independent acquisition.

    PubMed

    Hu, Alex; Noble, William S; Wolf-Yadlin, Alejandro

    2016-01-01

    The ultimate aim of proteomics is to fully identify and quantify the entire complement of proteins and post-translational modifications in biological samples of interest. For the last 15 years, liquid chromatography-tandem mass spectrometry (LC-MS/MS) in data-dependent acquisition (DDA) mode has been the standard for proteomics when sampling breadth and discovery were the main objectives; multiple reaction monitoring (MRM) LC-MS/MS has been the standard for targeted proteomics when precise quantification, reproducibility, and validation were the main objectives. Recently, improvements in mass spectrometer design and bioinformatics algorithms have resulted in the rediscovery and development of another sampling method: data-independent acquisition (DIA). DIA comprehensively and repeatedly samples every peptide in a protein digest, producing a complex set of mass spectra that is difficult to interpret without external spectral libraries. Currently, DIA approaches the identification breadth of DDA while achieving the reproducible quantification characteristic of MRM or its newest version, parallel reaction monitoring (PRM). In comparative de novo identification and quantification studies in human cell lysates, DIA identified up to 89% of the proteins detected in a comparable DDA experiment while providing reproducible quantification of over 85% of them. DIA analysis aided by spectral libraries derived from prior DIA experiments or auxiliary DDA data produces identification and quantification as reproducible and precise as that achieved by MRM/PRM, except on low‑abundance peptides that are obscured by stronger signals. DIA is still a work in progress toward the goal of sensitive, reproducible, and precise quantification without external spectral libraries. New software tools applied to DIA analysis have to deal with deconvolution of complex spectra as well as proper filtering of false positives and false negatives. However, the future outlook is positive, and various

  16. Contribution of developing advanced engineering methods in interdisciplinary studying the piston rings from 1.6 spark ignited Ford engine at Technical University of Cluj-Napoca

    NASA Astrophysics Data System (ADS)

    -Aurel Cherecheş, Ioan; -Ioana Borzan, Adela; -Laurean Băldean, Doru

    2017-10-01

    Study of construction and wearing process in the case of piston-rings and other significant components from internal combustion engines leads at any time to creative and useful optimizing ideas, both in designing and manufacturing phases. Main objective of the present paper is to realize an interdisciplinary research using advanced methods in piston-rings evaluation of a common vehicle on the streets which is Ford Focus FYDD. Specific objectives are a theoretical study of the idea for advanced analysis method in piston-rings evaluation and an applied research developed in at Technical University from Cluj-Napoca with the motor vehicle caught in the repairing process.

  17. Building a Prosperous Economy. Washington's Community and Technical Colleges

    ERIC Educational Resources Information Center

    Washington State Board for Community and Technical Colleges, 2014

    2014-01-01

    Washington's community and technical colleges are a collective, powerful, unmatched resource for advancing prosperity through education. These 34 colleges not only connect with employers in the regions where they operate, but also with each other through common programs--like advanced manufacturing and allied health--that align with Washington's…

  18. 78 FR 44104 - Notice of Intent To Issue a Funding Opportunity Announcement; Technical Assistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-23

    ... Funding Opportunity Announcement; Technical Assistance AGENCY: Federal Energy Management Program, Office.... This notice also is to inform Federal agencies of the availability of technical assistance in advance.... FOR FURTHER INFORMATION CONTACT: For requests for technical assistance regarding CHP, please contact...

  19. Identifying technical aliases in SELDI mass spectra of complex mixtures of proteins

    PubMed Central

    2013-01-01

    Background Biomarker discovery datasets created using mass spectrum protein profiling of complex mixtures of proteins contain many peaks that represent the same protein with different charge states. Correlated variables such as these can confound the statistical analyses of proteomic data. Previously we developed an algorithm that clustered mass spectrum peaks that were biologically or technically correlated. Here we demonstrate an algorithm that clusters correlated technical aliases only. Results In this paper, we propose a preprocessing algorithm that can be used for grouping technical aliases in mass spectrometry protein profiling data. The stringency of the variance allowed for clustering is customizable, thereby affecting the number of peaks that are clustered. Subsequent analysis of the clusters, instead of individual peaks, helps reduce difficulties associated with technically-correlated data, and can aid more efficient biomarker identification. Conclusions This software can be used to pre-process and thereby decrease the complexity of protein profiling proteomics data, thus simplifying the subsequent analysis of biomarkers by decreasing the number of tests. The software is also a practical tool for identifying which features to investigate further by purification, identification and confirmation. PMID:24010718

  20. Knowledge Acquisition and Job Training for Advanced Technical Skills Using Immersive Virtual Environment

    NASA Astrophysics Data System (ADS)

    Watanuki, Keiichi; Kojima, Kazuyuki

    The environment in which Japanese industry has achieved great respect is changing tremendously due to the globalization of world economies, while Asian countries are undergoing economic and technical development as well as benefiting from the advances in information technology. For example, in the design of custom-made casting products, a designer who lacks knowledge of casting may not be able to produce a good design. In order to obtain a good design and manufacturing result, it is necessary to equip the designer and manufacturer with a support system related to casting design, or a so-called knowledge transfer and creation system. This paper proposes a new virtual reality based knowledge acquisition and job training system for casting design, which is composed of the explicit and tacit knowledge transfer systems using synchronized multimedia and the knowledge internalization system using portable virtual environment. In our proposed system, the education content is displayed in the immersive virtual environment, whereby a trainee may experience work in the virtual site operation. Provided that the trainee has gained explicit and tacit knowledge of casting through the multimedia-based knowledge transfer system, the immersive virtual environment catalyzes the internalization of knowledge and also enables the trainee to gain tacit knowledge before undergoing on-the-job training at a real-time operation site.

  1. Advanced wind turbine near-term product development. Final technical report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    1996-01-01

    In 1990 the US Department of Energy initiated the Advanced Wind Turbine (AWT) Program to assist the growth of a viable wind energy industry in the US. This program, which has been managed through the National Renewable Energy Laboratory (NREL) in Golden, Colorado, has been divided into three phases: (1) conceptual design studies, (2) near-term product development, and (3) next-generation product development. The goals of the second phase were to bring into production wind turbines which would meet the cost goal of $0.05 kWh at a site with a mean (Rayleigh) windspeed of 5.8 m/s (13 mph) and a verticalmore » wind shear exponent of 0.14. These machines were to allow a US-based industry to compete domestically with other sources of energy and to provide internationally competitive products. Information is given in the report on design values of peak loads and of fatigue spectra and the results of the design process are summarized in a table. Measured response is compared with the results from mathematical modeling using the ADAMS code and is discussed. Detailed information is presented on the estimated costs of maintenance and on spare parts requirements. A failure modes and effects analysis was carried out and resulted in approximately 50 design changes including the identification of ten previously unidentified failure modes. The performance results of both prototypes are examined and adjusted for air density and for correlation between the anemometer site and the turbine location. The anticipated energy production at the reference site specified by NREL is used to calculate the final cost of energy using the formulas indicated in the Statement of Work. The value obtained is $0.0514/kWh in January 1994 dollars. 71 figs., 30 tabs.« less

  2. Wafer hot spot identification through advanced photomask characterization techniques

    NASA Astrophysics Data System (ADS)

    Choi, Yohan; Green, Michael; McMurran, Jeff; Ham, Young; Lin, Howard; Lan, Andy; Yang, Richer; Lung, Mike

    2016-10-01

    As device manufacturers progress through advanced technology nodes, limitations in standard 1-dimensional (1D) mask Critical Dimension (CD) metrics are becoming apparent. Historically, 1D metrics such as Mean to Target (MTT) and CD Uniformity (CDU) have been adequate for end users to evaluate and predict the mask impact on the wafer process. However, the wafer lithographer's process margin is shrinking at advanced nodes to a point that the classical mask CD metrics are no longer adequate to gauge the mask contribution to wafer process error. For example, wafer CDU error at advanced nodes is impacted by mask factors such as 3-dimensional (3D) effects and mask pattern fidelity on subresolution assist features (SRAFs) used in Optical Proximity Correction (OPC) models of ever-increasing complexity. These items are not quantifiable with the 1D metrology techniques of today. Likewise, the mask maker needs advanced characterization methods in order to optimize the mask process to meet the wafer lithographer's needs. These advanced characterization metrics are what is needed to harmonize mask and wafer processes for enhanced wafer hot spot analysis. In this paper, we study advanced mask pattern characterization techniques and their correlation with modeled wafer performance.

  3. Gender Equity in Trade and Technical Careers Curriculum.

    ERIC Educational Resources Information Center

    Vocational Curriculum Resource Center of Maine, Fairfield.

    This curriculum guide contains task performance guides for eight duties to be taught to prospective and inservice trade and technical education teachers in Maine. The duties involve eliminating sex bias and sex discrimination in school, on the job, and in self-identification. The eight duties described in the guide are the following: eliminating…

  4. Laboratory for Atmospheres: 2006 Technical Highlights

    NASA Technical Reports Server (NTRS)

    Stewart, Richard W.

    2007-01-01

    The 2006 Technical Highlights describes the efforts of all members of the Laboratory for Atmospheres. Their dedication to advancing Earth science through conducting research, developing and running models, designing instruments, managing projects, running field campaigns, and numerous other activities, are highlighted in this report.

  5. Laboratory for Atmospheres 2009 Technical Highlights

    NASA Technical Reports Server (NTRS)

    Cote, Charles E.

    2010-01-01

    The 2009 Technical Highlights describes the efforts of all members of the Laboratory for Atmospheres. Their dedication to advancing Earth Science through conducting research, developing and running models, designing instruments, managing projects, running field campaigns, and numerous other activities, is highlighted in this report.

  6. Laboratory for Atmospheres 2005 Technical Highlights

    NASA Technical Reports Server (NTRS)

    2006-01-01

    The 2005 Technical highlights describes the efforts of all members of the Laboratory for Atmospheres. Their dedication to advancing Earth Science through conducting research, developing and running models, designing instruments, managing projects, running field campaigns, and numerous other activities, is highlighted in this report.

  7. Laboratory for Atmospheres 2010 Technical Highlights

    NASA Technical Reports Server (NTRS)

    2011-01-01

    The 2010 Technical Highlights describes the efforts of all members of the Laboratory for Atmospheres. Their dedication to advancing Earth Science through conducting research, developing and running models, designing instruments, managing projects, running field campaigns, and numerous other activities, is highlighted in this report.

  8. Laboratory for Atmospheres 2007 Technical Highlights

    NASA Technical Reports Server (NTRS)

    Stewart, Richard W.

    2008-01-01

    The 2007 Technical Highlights describes the efforts of all members of the Laboratory for Atmospheres. Their dedication to advancing Earth Science through conducting research, developing and running models, designing instruments, managing projects, running field campaigns, and numerous other activities, is highlighted in this report.

  9. Advancing Free Flight Through Human Factors: Workshop Report

    DOT National Transportation Integrated Search

    1995-08-01

    This report describes the results of the Advancing Free Flight Through Human : Factors technical workshop held on June 20 and 21, 1995. The purpose of this : technical workshop was to begin the process of identifying and solving human : factors issue...

  10. High Tech and the Upward Mobility of Non-Technical People.

    ERIC Educational Resources Information Center

    Kammire, Linda L.

    The social and psychological effects of rapid technological advancement in the computer industry is the subject of this paper, which focuses on the concerns of people with non-technical backgrounds. It describes the career series, High Tech for Non-Technical People, created by the Georgia State University Career Development Center. The three…

  11. Technical Writing 1987: Galloping Off in at Least Two Directions.

    ERIC Educational Resources Information Center

    Stohrer, Freda F.

    Technical writing instructors generally agree about the absolute need for communication skills throughout the technological work place, but a survey of technical writing journal articles shows a lack of focus on ways to address business's needs for on-the-job literacy. One major advance within the profession in recent years has been the…

  12. Prototype instrument for noninvasive ultrasonic inspection and identification of fluids in sealed containers

    NASA Astrophysics Data System (ADS)

    Tucker, Brian J.; Diaz, Aaron A.; Eckenrode, Brian A.

    2006-05-01

    Government agencies and homeland security related organizations have identified the need to develop and establish a wide range of unprecedented capabilities for providing scientific and technical forensic services to investigations involving hazardous chemical, biological, and radiological materials, including extremely dangerous chemical and biological warfare agents. Pacific Northwest National Laboratory (PNNL) has developed a prototype portable, handheld, hazardous materials acoustic inspection prototype that provides noninvasive container interrogation and material identification capabilities using nondestructive ultrasonic velocity and attenuation measurements. Due to the wide variety of fluids as well as container sizes and materials encountered in various law enforcement inspection activities, the need for high measurement sensitivity and advanced ultrasonic measurement techniques were identified. The prototype was developed using a versatile electronics platform, advanced ultrasonic wave propagation methods, and advanced signal processing techniques. This paper primarily focuses on the ultrasonic measurement methods and signal processing techniques incorporated into the prototype. High bandwidth ultrasonic transducers combined with an advanced pulse compression technique allowed researchers to 1) obtain high signal-to-noise ratios and 2) obtain accurate and consistent time-of-flight (TOF) measurements through a variety of highly attenuative containers and fluid media. Results of work conducted in the laboratory have demonstrated that the prototype experimental measurement technique also provided information regarding container properties, which will be utilized in future container-independent measurements of hidden liquids.

  13. An assessment of individualized technical ear training for audio production.

    PubMed

    Kim, Sungyoung

    2015-07-01

    An individualized technical ear training method is compared to a non-individualized method. The efficacy of the individualized method is assessed using a standardized test conducted before and after the training period. Participants who received individualized training improved better than the control group on the test. Results indicate the importance of individualized training for acquisition of spectrum-identification and spectrum-matching skills. Individualized training, therefore, should be implemented by default into technical ear training programs used in audio production industry and education.

  14. 15 CFR 295.11 - Technical and educational services for ATP recipients.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS ADVANCED TECHNOLOGY PROGRAM General § 295.11 Technical and educational services for ATP recipients... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Technical and educational services for...

  15. Electronic Technology. Technical Committee Report.

    ERIC Educational Resources Information Center

    Idaho State Dept. of Education, Boise. Div. of Vocational Education.

    This Technical Committee Report prepared by industry representatives in Idaho lists the skills currently necessary for an employee in that state to obtain a job in electronic technology, retain a job once hired, and advance in that occupational field. (Task lists are grouped according to duty areas generally used in industry settings, and are used…

  16. Automotive Technology. Technical Committee Report.

    ERIC Educational Resources Information Center

    Idaho State Dept. of Education, Boise. Div. of Vocational Education.

    This Technical Committee Report prepared by industry representatives in Idaho lists the skills currently necessary for an employee in that state to obtain a job in automotive technology, retain a job once hired, and advance in that occupational field. (Task lists are grouped according to duty areas generally used in industry settings, and are used…

  17. Technological advancements and their importance for nematode identification

    NASA Astrophysics Data System (ADS)

    Ahmed, Mohammed; Sapp, Melanie; Prior, Thomas; Karssen, Gerrit; Back, Matthew Alan

    2016-06-01

    Nematodes represent a species-rich and morphologically diverse group of metazoans known to inhabit both aquatic and terrestrial environments. Their role as biological indicators and as key players in nutrient cycling has been well documented. Some plant-parasitic species are also known to cause significant losses to crop production. In spite of this, there still exists a huge gap in our knowledge of their diversity due to the enormity of time and expertise often involved in characterising species using phenotypic features. Molecular methodology provides useful means of complementing the limited number of reliable diagnostic characters available for morphology-based identification. We discuss herein some of the limitations of traditional taxonomy and how molecular methodologies, especially the use of high-throughput sequencing, have assisted in carrying out large-scale nematode community studies and characterisation of phytonematodes through rapid identification of multiple taxa. We also provide brief descriptions of some the current and almost-outdated high-throughput sequencing platforms and their applications in both plant nematology and soil ecology.

  18. Multidimensional protein identification technology (MudPIT): technical overview of a profiling method optimized for the comprehensive proteomic investigation of normal and diseased heart tissue.

    PubMed

    Kislinger, Thomas; Gramolini, Anthony O; MacLennan, David H; Emili, Andrew

    2005-08-01

    An optimized analytical expression profiling strategy based on gel-free multidimensional protein identification technology (MudPIT) is reported for the systematic investigation of biochemical (mal)-adaptations associated with healthy and diseased heart tissue. Enhanced shotgun proteomic detection coverage and improved biological inference is achieved by pre-fractionation of excised mouse cardiac muscle into subcellular components, with each organellar fraction investigated exhaustively using multiple repeat MudPIT analyses. Functional-enrichment, high-confidence identification, and relative quantification of hundreds of organelle- and tissue-specific proteins are achieved readily, including detection of low abundance transcriptional regulators, signaling factors, and proteins linked to cardiac disease. Important technical issues relating to data validation, including minimization of artifacts stemming from biased under-sampling and spurious false discovery, together with suggestions for further fine-tuning of sample preparation, are discussed. A framework for follow-up bioinformatic examination, pattern recognition, and data mining is also presented in the context of a stringent application of MudPIT for probing fundamental aspects of heart muscle physiology as well as the discovery of perturbations associated with heart failure.

  19. Advancements in the safe identification of explosives using a Raman handheld instrument (ACE-ID)

    NASA Astrophysics Data System (ADS)

    Arnó, Josep; Frunzi, Michael; Kittredge, Marina; Sparano, Brian

    2014-05-01

    Raman spectroscopy is the technology of choice to identify bulk solid and liquid phase unknown samples without the need to contact the substance. Materials can be identified through transparent and semi-translucent containers such as plastic and glass. ConOps in emergency response and military field applications require the redesign of conventional laboratory units for: field portability; shock, thermal and chemical attack resistance; easy and intuitive use in restrictive gear; reduced size, weight, and power. This article introduces a new handheld instrument (ACE-IDTM) designed to take Raman technology to the next level in terms of size, safety, speed, and analytical performance. ACE-ID is ruggedized for use in severe climates and terrains. It is lightweight and can be operated with just one hand. An intuitive software interface guides users through the entire identification process, making it easy-to-use by personnel of different skill levels including military explosive ordinance disposal technicians, civilian bomb squads and hazmat teams. Through the use of embedded advanced algorithms, the instrument is capable of providing fluorescence correction and analysis of binary mixtures. Instrument calibration is performed automatically upon startup without requiring user intervention. ACE-ID incorporates an optical rastering system that diffuses the laser energy over the sample. This important innovation significantly reduces the heat induced in dark samples and the probability of ignition of susceptible explosive materials. In this article, the explosives identification performance of the instrument will be provided in addition to a quantitative evaluation of the safety improvements derived from the reduced ignition probabilities.

  20. System identification of jet engines

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sugiyama, N.

    2000-01-01

    System identification plays an important role in advanced control systems for jet engines, in which controls are performed adaptively using data from the actual engine and the identified engine. An identification technique for jet engine using the Constant Gain Extended Kalman Filter (CGEKF) is described. The filter is constructed for a two-spool turbofan engine. The CGEKF filter developed here can recognize parameter change in engine components and estimate unmeasurable variables over whole flight conditions. These capabilities are useful for an advanced Full Authority Digital Electric Control (FADEC). Effects of measurement noise and bias, effects of operating point and unpredicted performancemore » change are discussed. Some experimental results using the actual engine are shown to evaluate the effectiveness of CGEKF filter.« less

  1. Autobody Technology. Technical Committee Report.

    ERIC Educational Resources Information Center

    Idaho State Dept. of Education, Boise. Div. of Vocational Education.

    This Technical Committee Report prepared by industry representatives in Idaho lists the skills currently necessary for an employee in that state to obtain a job in autobody technology, retain a job once hired, and advance in that occupational field. (Task lists are grouped according to duty areas generally used in industry settings and are used as…

  2. 48 CFR 1631.205-76 - Trade, business, technical, and professional activity costs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Trade, business, technical....205-76 Trade, business, technical, and professional activity costs. (a) FEHBP participating plans, carriers, and underwriters shall seek the advance written approval of the contracting officer for...

  3. Technical Advances and Fifth Grade Reading Comprehension: Do Students Benefit?

    ERIC Educational Resources Information Center

    Fountaine, Drew

    This paper takes a look at some recent studies on utilization of technical tools, primarily personal computers and software, for improving fifth-grade students' reading comprehension. Specifically, the paper asks what benefits an educator can expect students to derive from closed-captioning and computer-assisted reading comprehension products. It…

  4. Technical Degrees and Higher Vocational Education

    ERIC Educational Resources Information Center

    Hordern, Jim

    2017-01-01

    This paper focuses on the proposals for the introduction of "technical degrees" in English higher education institutions advanced by the Labour Party's Liam Byrne in a document entitled "Robbins Rebooted" which was published in August 2014 by the Social Market Foundation. The context and rationale for the proposed technical…

  5. Extensible Markup Language: How Might It Alter the Software Documentation Process and the Role of the Technical Communicator?

    ERIC Educational Resources Information Center

    Battalio, John T.

    2002-01-01

    Describes the influence that Extensible Markup Language (XML) will have on the software documentation process and subsequently on the curricula of advanced undergraduate and master's programs in technical communication. Recommends how curricula of advanced undergraduate and master's programs in technical communication ought to change in order to…

  6. Technical advances and pitfalls on the way to human cloning.

    PubMed

    Mollard, Richard; Denham, Mark; Trounson, Alan

    2002-03-01

    There exists a widespread consensus that the cloning of human beings to term would be detrimental to both the mother and child and of little value to society. However, the ambition of a few organisations and the recent advances in cellular and molecular technologies that led to the cloning of Dolly the sheep, for example, have meant that such a procedure will be possible if not illegal in the near future. The science associated with the cloning technologies practiced in other mammalian species reported to date provide important advances in our understanding of how cells function during early developmental processes and commit themselves to specific developmental pathways. However, many technological insufficiencies remain. Both technological advances and several of the associated insufficiencies are outlined in this review.

  7. The Design and Transfer of Advanced Command and Control (C2) Computer-Based Systems

    DTIC Science & Technology

    1980-03-31

    TECHNICAL REPORT 80-02 QUARTERLY TECHNICAL REPORT: THE DESIGN AND TRANSFER OF ADVANCED COMMAND AND CONTROL (C 2 ) COMPUTER-BASED SYSTEMS ARPA...The Tasks/Objectives and/or Purposes of the overall project are connected with the design , development, demonstration and transfer of advanced...command and control (C2 ) computer-based systems; this report covers work in the computer-based design and transfer areas only. The Technical Problems thus

  8. Advanced Learning Theories Applied to Leadership Development

    DTIC Science & Technology

    2006-11-01

    Theory . We combined the cognitive , experiential and motivational components of advanced learning theories to develop a training application...Center for Army Leadership Technical Report 2006-2 Advanced Learning Theories Applied to Leadership Development Christina Curnow...2006 5a. CONTRACT NUMBER W91QF4-05-F-0026 5b. GRANT NUMBER 4. TITLE AND SUBTITLE Advanced Learning Theories Applied to Leadership Development 5c

  9. NASA Institute for Advanced Concepts

    NASA Technical Reports Server (NTRS)

    Cassanova, Robert A.

    1999-01-01

    The purpose of NASA Institute for Advanced Concepts (NIAC) is to provide an independent, open forum for the external analysis and definition of space and aeronautics advanced concepts to complement the advanced concepts activities conducted within the NASA Enterprises. The NIAC will issue Calls for Proposals during each year of operation and will select revolutionary advanced concepts for grant or contract awards through a peer review process. Final selection of awards will be with the concurrence of NASA's Chief Technologist. The operation of the NIAC is reviewed biannually by the NIAC Science, Exploration and Technology Council (NSETC) whose members are drawn from the senior levels of industry and universities. The process of defining the technical scope of the initial Call for Proposals was begun with the NIAC "Grand Challenges" workshop conducted on May 21-22, 1998 in Columbia, Maryland. These "Grand Challenges" resulting from this workshop became the essence of the technical scope for the first Phase I Call for Proposals which was released on June 19, 1998 with a due date of July 31, 1998. The first Phase I Call for Proposals attracted 119 proposals. After a thorough peer review, prioritization by NIAC and technical concurrence by NASA, sixteen subgrants were awarded. The second Phase I Call for Proposals was released on November 23, 1998 with a due date of January 31, 1999. Sixty-three (63) proposals were received in response to this Call. On December 2-3, 1998, the NSETC met to review the progress and future plans of the NIAC. The next NSETC meeting is scheduled for August 5-6, 1999. The first Phase II Call for Proposals was released to the current Phase I grantees on February 3,1999 with a due date of May 31, 1999. Plans for the second year of the contract include a continuation of the sequence of Phase I and Phase II Calls for Proposals and hosting the first NIAC Annual Meeting and USRA/NIAC Technical Symposium in NASA HQ.

  10. 48 CFR 2131.205-43 - Trade, business, technical and professional activity costs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Trade, business, technical... Organizations 2131.205-43 Trade, business, technical and professional activity costs. (a) FEGLI Program contractors shall seek the advance written approval of the contracting officer for allowability of all or part...

  11. Advanced forensic validation for human spermatozoa identification using SPERM HY-LITER™ Express with quantitative image analysis.

    PubMed

    Takamura, Ayari; Watanabe, Ken; Akutsu, Tomoko

    2017-07-01

    Identification of human semen is indispensable for the investigation of sexual assaults. Fluorescence staining methods using commercial kits, such as the series of SPERM HY-LITER™ kits, have been useful to detect human sperm via strong fluorescence. These kits have been examined from various forensic aspects. However, because of a lack of evaluation methods, these studies did not provide objective, or quantitative, descriptions of the results nor clear criteria for the decisions reached. In addition, the variety of validations was considerably limited. In this study, we conducted more advanced validations of SPERM HY-LITER™ Express using our established image analysis method. Use of this method enabled objective and specific identification of fluorescent sperm's spots and quantitative comparisons of the sperm detection performance under complex experimental conditions. For body fluid mixtures, we examined interference with the fluorescence staining from other body fluid components. Effects of sample decomposition were simulated in high humidity and high temperature conditions. Semen with quite low sperm concentrations, such as azoospermia and oligospermia samples, represented the most challenging cases in application of the kit. Finally, the tolerance of the kit against various acidic and basic environments was analyzed. The validations herein provide useful information for the practical applications of the SPERM HY-LITER™ Express kit, which were previously unobtainable. Moreover, the versatility of our image analysis method toward various complex cases was demonstrated.

  12. The Rock Valley College Career Advancement Program.

    ERIC Educational Resources Information Center

    Rock Valley Coll., Rockford, IL.

    The Career Advancement Program (CAP) is a joint effort by a 2-year college and industrial firms in its district to expand educational opportunities, to match college programs to local needs, and to help industry meet its present and future technical manpower needs. CAP has worked to attract students, full- or part-time, to technical training.…

  13. Advanced Life Support Systems

    NASA Technical Reports Server (NTRS)

    Barta, Daniel J.

    2004-01-01

    This presentation is planned to be a 10-15 minute "catalytic" focused presentation to be scheduled during one of the working sessions at the TIM. This presentation will focus on Advanced Life Support technologies key to future human Space Exploration as outlined in the Vision, and will include basic requirements, assessment of the state-of-the-art and gaps, and include specific technology metrics. The presentation will be technical in character, lean heavily on data in published ALS documents (such as the Baseline Values and Assumptions Document) but not provide specific technical details or build to information on any technology mentioned (thus the presentation will be benign from an export control and a new technology perspective). The topics presented will be focused on the following elements of Advanced Life Support: air revitalization, water recovery, waste management, thermal control, habitation systems, food systems and bioregenerative life support.

  14. NREL Advances Wells Fargo Innovation Incubator Projects | Energy Systems

    Science.gov Websites

    Integration Facility | NREL NREL Advances Wells Fargo Innovation Incubator Projects NREL Advances Wells Fargo Innovation Incubator Projects NREL has provided technical support and validation testing at the ESIF to help advance Wells Fargo Innovation Incubator (IN2) projects. The IN2 program helps

  15. Advanced Respiratory Motion Compensation for Coronary MR Angiography

    PubMed Central

    Henningsson, Markus; Botnar, Rene M.

    2013-01-01

    Despite technical advances, respiratory motion remains a major impediment in a substantial amount of patients undergoing coronary magnetic resonance angiography (CMRA). Traditionally, respiratory motion compensation has been performed with a one-dimensional respiratory navigator positioned on the right hemi-diaphragm, using a motion model to estimate and correct for the bulk respiratory motion of the heart. Recent technical advancements has allowed for direct respiratory motion estimation of the heart, with improved motion compensation performance. Some of these new methods, particularly using image-based navigators or respiratory binning, allow for more advanced motion correction which enables CMRA data acquisition throughout most or all of the respiratory cycle, thereby significantly reducing scan time. This review describes the three components typically involved in most motion compensation strategies for CMRA, including respiratory motion estimation, gating and correction, and how these processes can be utilized to perform advanced respiratory motion compensation. PMID:23708271

  16. The decay of NASA's technical culture

    NASA Technical Reports Server (NTRS)

    Mccurdy, Howard E.

    1989-01-01

    Changes in the organization structure and technical research activities of NASA since 1970 are evaluated. The creation of NASA and the original organizational structure and operation of NASA are reviewed. The relationship between organization and advanced technology is discussed and suggestions are given for ways of maintaining NASA as a high reliability organization.

  17. Synthetic biology and the technicity of biofuels.

    PubMed

    Mackenzie, Adrian

    2013-06-01

    The principal existing real-world application of synthetic biology is biofuels. Several 'next generation biofuel' companies-Synthetic Genomics, Amyris and Joule Unlimited Technologies-claim to be using synthetic biology to make biofuels. The irony of this is that highly advanced science and engineering serves the very mundane and familiar realm of transport. Despite their rather prosaic nature, biofuels could offer an interesting way to highlight the novelty of synthetic biology from several angles at once. Drawing on the French philosopher of technology and biology Gilbert Simondon, we can understand biofuels as technical objects whose genesis involves processes of concretisation that negotiate between heterogeneous geographical, biological, technical, scientific and commercial realities. Simondon's notion of technicity, the degree of concretisation of a technical object, usefully conceptualises this relationality. Viewed in terms of technicity, we might understand better how technical entities, elements, and ensembles are coming into being in the name of synthetic biology. The broader argument here is that when we seek to identify the newness of disciplines, their newness might be less epistemic and more logistic. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.

  18. DNA methods for identification of Chinese medicinal materials

    PubMed Central

    Yip, Pui Ying; Chau, Chi Fai; Mak, Chun Yin; Kwan, Hoi Shan

    2007-01-01

    As adulterated and substituted Chinese medicinal materials are common in the market, therapeutic effectiveness of such materials cannot be guaranteed. Identification at species-, strain- and locality-levels, therefore, is required for quality assurance/control of Chinese medicine. This review provides an informative introduction to DNA methods for authentication of Chinese medicinal materials. Technical features and examples of the methods based on sequencing, hybridization and polymerase chain reaction (PCR) are described and their suitability for different identification objectives is discussed. PMID:17803808

  19. Technical and physical determinants of soccer match-play performance in elite youth soccer players.

    PubMed

    Rowat, Owain; Fenner, Jonathan; Unnithan, Viswanath

    2017-04-01

    The aim of this study was to evaluate whether physical performance characteristics could be a better predictor than technical skills in determining the technical level of county soccer players in a match situation. With institutional ethics approval, 25 male youth soccer players aged 16-18.5 years from a professional soccer academy in South East Asia were selected and height and body mass were recorded. Players were tested for sexual maturity (pubertal development scale [PDS] self-assessment), aerobic capacity (yo-yo intermittent recovery test level 1 [YYIR1]), repeated sprint ability (7 x 35 m sprints) acceleration (15 m sprint) and four soccer skills tests (dribble with pass, dribbling speed, passing and shooting accuracy). Players' technical ability during match play was assessed in small-sided games of soccer (5 v 5) using a novel game technical scoring chart (scoring chart completed by coaches to assess technical performance in a match situation) developed from criteria (e.g., first touch, dribbling and two footedness) used by youth soccer coaches for talent identification. A Spearman's rank correlation showed the YYIR1 test and 15 m sprint test were limited in predicting technical match performance (r=0.03, P=0.88, r=-0.23, P=0.32 respectively). A Pearson product moment correlation showed that the repeated sprint test was also limited in predicting technical match performance (r=-0.34, P=0.14). A dribbling skill with a pass was found to be the best determinant of a player's technical ability in a match (r=-0.57, P=0.00). Talent identification and selection programs in Asian youth soccer should include a dribbling skill performed with a pass.

  20. Advanced composites technology program

    NASA Technical Reports Server (NTRS)

    Davis, John G., Jr.

    1993-01-01

    This paper provides a brief overview of the NASA Advanced Composites Technology (ACT) Program. Critical technology issues that must be addressed and solved to develop composite primary structures for transport aircraft are delineated. The program schedule and milestones are included. Work completed in the first 3 years of the program indicates the potential for achieving composite structures that weigh less and are cost effective relative to conventional aluminum structure. Selected technical accomplishments are noted. Readers who are seeking more in-depth technical information should study the other papers included in these proceedings.

  1. Technical Adequacy of Early Numeracy Curriculum-Based Measurement in Kindergarten

    ERIC Educational Resources Information Center

    Martinez, Rebecca S.; Missall, Kristen N.; Graney, Suzanne Bamonto; Aricak, O. Tolga; Clarke, Ben

    2009-01-01

    The current study examines the technical adequacy of four Early Numeracy Curriculum-Based Measurement (EN-CBM) screening tasks: "Oral Counting" (OC), "Number Identification" (NI), "Quantity Discrimination" (QD), and "Missing Number" (MN). Results from 59 kindergarten students assessed in the fall and spring reveal moderate to high test-retest and…

  2. Coherent anti-Stokes Raman scattering microscopy: overcoming technical barriers for clinical translation

    PubMed Central

    Tu, Haohua; Boppart, Stephen A.

    2015-01-01

    Clinical translation of coherent anti-Stokes Raman scattering microscopy is of great interest because of the advantages of noninvasive label-free imaging, high sensitivity, and chemical specificity. For this to happen, we have identified and review the technical barriers that must be overcome. Prior investigations have developed advanced techniques (features), each of which can be used to effectively overcome one particular technical barrier. However, the implementation of one or a small number of these advanced features in previous attempts for clinical translation has often introduced more tradeoffs than benefits. In this review, we outline a strategy that would integrate multiple advanced features to overcome all the technical barriers simultaneously, effectively reduce tradeoffs, and synergistically optimize CARS microscopy for clinical translation. The operation of the envisioned system incorporates coherent Raman micro-spectroscopy for identifying vibrational biomolecular markers of disease and single-frequency (or hyperspectral) Raman imaging of these specific biomarkers for real-time in vivo diagnostics and monitoring. An optimal scheme of clinical CARS micro-spectroscopy for thin ex vivo tissues. PMID:23674234

  3. Advancing Research in the National Science Foundation's Advanced Technological Education Program

    ERIC Educational Resources Information Center

    Wingate, Lori A.

    2017-01-01

    Advanced Technological Education is distinct from typical National Science Foundation programs in that it is essentially a training--not research--program, and most grantees are located at technical and two-year colleges. This article presents empirical data on the status of research in the program, discusses the program's role in supporting NSF's…

  4. Drafting & Design Technology. Technical Committee Report.

    ERIC Educational Resources Information Center

    Idaho State Dept. of Education, Boise. Div. of Vocational Education.

    This Technical Committee Report prepared by industry representatives in Idaho lists the skills currently necessary for an employee in that state to obtain a job in drafting and design technology, retain a job once hired, and advance in that occupational field. (Task lists are grouped according to duty areas generally used in industry settings, and…

  5. Applied Welding Technology. Technical Committee Report.

    ERIC Educational Resources Information Center

    Idaho State Dept. of Education, Boise. Div. of Vocational Education.

    This Technical Committee Report prepared by industry representatives in Idaho lists the skills currently necessary for an employee in that state to obtain a job in applied welding technology, retain a job once hired, and advance in that occupational field. (Task lists are grouped according to duty areas generally used in industry settings, and are…

  6. Industrial Maintenance Technology. Technical Committee Report.

    ERIC Educational Resources Information Center

    Idaho State Dept. of Education, Boise. Div. of Vocational Education.

    This Technical Committee Report prepared by industry representatives in Idaho lists the skills currently necessary for an employee in that state to obtain a job in industrial maintenance technology, retain a job once hired, and advance in that occupational field. (Task lists are grouped according to duty areas generally used in industry settings,…

  7. Precision Machining Technology. Technical Committee Report.

    ERIC Educational Resources Information Center

    Idaho State Dept. of Education, Boise. Div. of Vocational Education.

    This Technical Committee Report prepared by industry representatives in Idaho lists the skills currently necessary for an employee in that state to obtain a job in precision machining technology, retain a job once hired, and advance in that occupational field. (Task lists are grouped according to duty areas generally used in industry settings, and…

  8. Business Systems Specialist. Technical Committee Report.

    ERIC Educational Resources Information Center

    Idaho State Dept. of Education, Boise. Div. of Vocational Education.

    This Technical Committee Report prepared by industry representatives in Idaho lists the skills currently necessary for an employee in that state to obtain a job as a business systems specialist, retain a job once hired, and advance in that occupational field. (Task lists are grouped according to duty areas generally used in industry settings, and…

  9. NearSense - Advances Towards a Silicon-Based Terahertz Near-Field Imaging Sensor for Ex Vivo Breast Tumour Identification

    NASA Astrophysics Data System (ADS)

    Mavarani, Laven; Hillger, Philipp; Bücher, Thomas; Grzyb, Janusz; Pfeiffer, Ullrich R.; Cassar, Quentin; Al-Ibadi, Amel; Zimmer, Thomas; Guillet, Jean-Paul; Mounaix, Patrick; MacGrogan, Gaëtan

    2018-03-01

    Breast Cancer is one of the most frequently diagnosed cancer diseases worldwide, and the most common invasive tumour for women. As with all cancers, early detection plays a major role in reducing the mortality and morbidity rate. Currently, most breast cancers are detected due to clinical symptoms, or by screening mammography. The limitations of these techniques have resulted in research of alternative methods for imaging and detecting breast cancer. Apart from this, it is essential to define precise tumour margins during breast-conserving surgeries to reduce the re-excision rate. This study presents the advances in the development of a silicon-based THz sub-wavelength imager usable in life science applications, especially for tumour margin identification.

  10. Incorporation of Radio Frequency Identification Tag in Dentures to Facilitate Recognition and Forensic Human Identification

    PubMed Central

    Nuzzolese, E; Marcario, V; Di Vella, G

    2010-01-01

    Forensic identification using odontology is based on the comparison of ante-mortem and post mortem dental records. The insertion of a radio frequency identification (RFId) tag into dentures could be used as an aid to identify decomposed bodies, by storing personal identification data in a small transponder that can be radio-transmitted to a reader connected to a computer. A small passive, 12 x 2,1 mm, read-only RFId-tag was incorporated into the manufacture of three trial complete upper dentures and tested for a signal. The aim of this article is to demonstrate the feasibility of manufacturing such a dental prosthesis, the technical protocols for its implantation in the denture resin and its working principles. Future research and tests are required in order to verify human compatibility of the tagged denture and also to evaluate any potential deterioration in strength when subjected to high temperatures, or for damage resulting from everyday wear and tear. It should also be able to withstand the extreme conditions resulting from major accidents or mass disasters and procedures used to perform a forensic identification. PMID:20657641

  11. Advanced Materials in Support of EERE Needs to Advance Clean Energy Technologies Program Implementation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liby, Alan L; Rogers, Hiram

    The goal of this activity was to carry out program implementation and technical projects in support of the ARRA-funded Advanced Materials in Support of EERE Needs to Advance Clean Energy Technologies Program of the DOE Advanced Manufacturing Office (AMO) (formerly the Industrial Technologies Program (ITP)). The work was organized into eight projects in four materials areas: strategic materials, structural materials, energy storage and production materials, and advanced/field/transient processing. Strategic materials included work on titanium, magnesium and carbon fiber. Structural materials included work on alumina forming austentic (AFA) and CF8C-Plus steels. The advanced batteries and production materials projects included work onmore » advanced batteries and photovoltaic devices. Advanced/field/transient processing included work on magnetic field processing. Details of the work in the eight projects are available in the project final reports which have been previously submitted.« less

  12. Advanced light source: Compendium of user abstracts and technical reports,1993-1996

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    1997-04-01

    This compendium contains abstracts written by users summarizing research completed or in progress from 1993-1996, ALS technical reports describing ongoing efforts related to improvement in machine operations and research and development projects, and information on ALS beamlines planned through 1998. Two tables of contents organize the user abstracts by beamline and by area of research, and an author index makes abstracts accessible by author and by principal investigator. Technical details for each beamline including whom to contact for additional information can be found in the beamline information section. Separate abstracts have been indexed into the database for contributions to thismore » compendium.« less

  13. Accurate Identification of Cancerlectins through Hybrid Machine Learning Technology.

    PubMed

    Zhang, Jieru; Ju, Ying; Lu, Huijuan; Xuan, Ping; Zou, Quan

    2016-01-01

    Cancerlectins are cancer-related proteins that function as lectins. They have been identified through computational identification techniques, but these techniques have sometimes failed to identify proteins because of sequence diversity among the cancerlectins. Advanced machine learning identification methods, such as support vector machine and basic sequence features (n-gram), have also been used to identify cancerlectins. In this study, various protein fingerprint features and advanced classifiers, including ensemble learning techniques, were utilized to identify this group of proteins. We improved the prediction accuracy of the original feature extraction methods and classification algorithms by more than 10% on average. Our work provides a basis for the computational identification of cancerlectins and reveals the power of hybrid machine learning techniques in computational proteomics.

  14. Advanced Fuels Campaign FY 2015 Accomplishments Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Braase, Lori Ann; Carmack, William Jonathan

    2015-10-29

    The mission of the Advanced Fuels Campaign (AFC) is to perform research, development, and demonstration (RD&D) activities for advanced fuel forms (including cladding) to enhance the performance and safety of the nation’s current and future reactors; enhance proliferation resistance of nuclear fuel; effectively utilize nuclear energy resources; and address the longer-term waste management challenges. This report is a compilation of technical accomplishment summaries for FY-15. Emphasis is on advanced accident-tolerant LWR fuel systems, advanced transmutation fuels technologies, and capability development.

  15. Reliability and Validity of Advanced Phonics Measures

    ERIC Educational Resources Information Center

    Doty, Sara J.; Hixson, Michael D.; Decker, Dawn M.; Reynolds, Jennifer L.; Drevon, Daniel D.

    2015-01-01

    Two studies explored the technical adequacy of various measures of advanced phonics skills. In Study 1, the advanced phonics measures consisted of pseudowords, real words, or a combination of both. Participants included 39 students in the third grade. Test-retest correlations for all measures were above 0.8 and interrater reliability was high.…

  16. Modern plant metabolomics: Advanced natural product gene discoveries, improved technologies, and future prospects

    DOE PAGES

    Sumner, Lloyd W.; Lei, Zhentian; Nikolau, Basil J.; ...

    2014-10-24

    Plant metabolomics has matured and modern plant metabolomics has accelerated gene discoveries and the elucidation of a variety of plant natural product biosynthetic pathways. This study highlights specific examples of the discovery and characterization of novel genes and enzymes associated with the biosynthesis of natural products such as flavonoids, glucosinolates, terpenoids, and alkaloids. Additional examples of the integration of metabolomics with genome-based functional characterizations of plant natural products that are important to modern pharmaceutical technology are also reviewed. This article also provides a substantial review of recent technical advances in mass spectrometry imaging, nuclear magnetic resonance imaging, integrated LC-MS-SPE-NMR formore » metabolite identifications, and x-ray crystallography of microgram quantities for structural determinations. The review closes with a discussion on the future prospects of metabolomics related to crop species and herbal medicine.« less

  17. 48 CFR 11.201 - Identification and availability of specifications.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Identification and... nongovernment standards, including voluntary consensus standards, from the National Technical Information... obtain from the DoDSSP those nongovernment standards, including voluntary consensus standards, adopted...

  18. Advanced technology for future regional transport aircraft

    NASA Technical Reports Server (NTRS)

    Williams, L. J.

    1982-01-01

    In connection with a request for a report coming from a U.S. Senate committee, NASA formed a Small Transport Aircraft Technology (STAT) team in 1978. STAT was to obtain information concerning the technical improvements in commuter aircraft that would likely increase their public acceptance. Another area of study was related to questions regarding the help which could be provided by NASA's aeronautical research and development program to commuter aircraft manufacturers with respect to the solution of technical problems. Attention is given to commuter airline growth, current commuter/region aircraft and new aircraft in development, prospects for advanced technology commuter/regional transports, and potential benefits of advanced technology. A list is provided of a number of particular advances appropriate to small transport aircraft, taking into account small gas turbine engine component technology, propeller technology, three-dimensional wing-design technology, airframe aerodynamics/propulsion integration, and composite structure materials.

  19. Technical Advancements in Simulator-Based Weapons Team Training.

    DTIC Science & Technology

    1991-04-01

    Acting Head H.C. OKRASKI, Director Advanced Simulation Concepts Research and Engineering Division Department SPECIAL REPORT 91-003 GOVERNMENT RIGHTS...City. State, and ZWCode)I12350 Research Parkway Orlando-, FL 32826-3224 SS... NAME OF FUNDING / SPONSORING 8 b. OFFICE SYMBOL 9. PROCUREMENT INSTRUMENT...necessary and idmntify’ by block number) The research and development reported here represents one phase of a broader effort to improve the

  20. Talent identification in youth soccer.

    PubMed

    Unnithan, Viswanath; White, Jordan; Georgiou, Andreas; Iga, John; Drust, Barry

    2012-01-01

    The purpose of this review article was firstly to evaluate the traditional approach to talent identification in youth soccer and secondly present pilot data on a more holistic method for talent identification. Research evidence exists to suggest that talent identification mechanisms that are predicated upon the physical (anthropometric) attributes of the early maturing individual only serve to identify current performance levels. Greater body mass and stature have both been related to faster ball shooting speed and vertical jump capacity respectively in elite youth soccer players. This approach, however, may prematurely exclude those late maturing individuals. Multiple physiological measures have also been used in an effort to determine key predictors of performance; with agility and sprint times, being identified as variables that could discriminate between elite and sub-elite groups of adolescent soccer players. Successful soccer performance is the product of multiple systems interacting with one another. Consequently, a more holistic approach to talent identification should be considered. Recent work, with elite youth soccer players, has considered whether multiple small-sided games could act as a talent identification tool in this population. The results demonstrated that there was a moderate agreement between the more technically gifted soccer player and success during multiple small-sided games.

  1. [Technical advancement improves survival in patients with locally advanced non-small cell lung cancer (LA-NSCLC) receiving definitive radiotherapy].

    PubMed

    Wang, J B; Jiang, W; Ji, Z; Cao, J Z; Liu, L P; Men, Y; Xu, C; Wang, X Z; Hui, Z G; Liang, J; Lyu, J M; Zhou, Z M; Xiao, Z F; Feng, Q F; Chen, D F; Zhang, H X; Yin, W B; Wang, L H

    2016-08-01

    This study aimed to evaluate the impact of technical advancement of radiation therapy in patients with LA-NSCLC receiving definitive radiotherapy (RT). Patients treated with definitive RT (≥50 Gy) between 2000 and 2010 were retrospectively reviewed. Overall survival (OS), cancer specific survival (CSS), locoregional progression-free survival (LRPFS), distant metastasis-free survival (DMFS) and progression-free survival (PFS) were calculated and compared among patients irradiated with different techniques. Radiation-induced lung injury (RILI) and esophageal injury (RIEI) were assessed according to the National Cancer Institute Common Terminology Criteria for Adverse Events 3.0 (NCI-CTCAE 3.0). A total of 946 patients were eligible for analysis, including 288 treated with two-dimensional radiotherapy (2D-RT), 209 with three-dimensional conformal radiation therapy (3D-CRT) and 449 with intensity-modulated radiation therapy (IMRT) respectively. The median follow-up time for the whole population was 84.1 months. The median OS of 2D-RT, 3D-CRT and IMRT groups were 15.8, 19.7 and 23.3 months, respectively, with the corresponding 5-year survival rate of 8.7%, 13.0% and 18.8%, respectively (P<0.001). The univariate analysis demonstrated significantly inferior OS, LRPFS, DMFS and PFS of 2D-RT than those provided by 3D-CRT or IMRT. The univariate analysis also revealed that the IMRT group had significantly loger LRPFS and a trend toward better OS and DMFS compared with 3D-CRT. Multivariate analysis showed that TNM stage, RT technique and KPS were independent factors correlated with all survival indexes. Compared with 2D-RT, the utilization of IMRT was associated with significantly improved OS, LRPFS, DMFS as well as PFS. Compared with 3D-CRT, IMRT provided superior DMFS (P=0.035), a trend approaching significance with regard to LRPFS (P=0.073) but no statistically significant improvement on OS, CSS and PFS in multivariate analysis. The incidence rates of RILI were

  2. Identification of resources and skills developed by partners of patients with advanced colon cancer: a qualitative study.

    PubMed

    Meunier-Beillard, N; Ponthier, N; Lepage, C; Gagnaire, A; Gheringuelli, F; Bengrine, L; Boudrant, A; Rambach, L; Quipourt, V; Devilliers, H; Lejeune, Catherine

    2018-06-05

    Family caregivers play an important role in caring for patients with advanced cancer. To become competent, individuals must draw on and mobilise an adequate combination of resources. Our goal was to identify the skills developed by caregivers of patients with advanced cancer and the associated resources mobilised. We chose to do it with partners of patients with colon cancer. The study used a cross-sectional qualitative design based on 20 individual interviews and a focus group. Partners were recruited from patients treated in three hospitals of France. Semi-structured interviews were conducted until data saturation was achieved. Each interview was transcribed verbatim, and thematic analyses were performed to extract significant themes and subthemes. Results from the individual and focus group interviews showed that the skills implemented by the partners (in domains of social relationships and health, domestic, organisational, emotional and well-being dimensions) were singular constructs, dependant on if resources (personal, external and schemes) may have been missing and insufficient. In addition, partners may have had these resources but not mobilised them. The identification of the skills and associated resources could allow healthcare professionals better identifying and understanding of the difficulties met by partners in taking care of patients. This could enable them to offer appropriate support to help the caregivers in their accompaniment.

  3. PINS Spectrum Identification Guide

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    A.J. Caffrey

    2012-03-01

    The Portable Isotopic Neutron Spectroscopy—PINS, for short—system identifies the chemicals inside munitions and containers without opening them, a decided safety advantage if the fill chemical is a hazardous substance like a chemical warfare agent or an explosive. The PINS Spectrum Identification Guide is intended as a reference for technical professionals responsible for the interpretation of PINS gamma-ray spectra. The guide is divided into two parts. The three chapters that constitute Part I cover the science and technology of PINS. Neutron activation analysis is the focus of Chapter 1. Chapter 2 explores PINS hardware, software, and related operational issues. Gamma-ray spectralmore » analysis basics are introduced in Chapter 3. The six chapters of Part II cover the identification of PINS spectra in detail. Like the PINS decision tree logic, these chapters are organized by chemical element: phosphorus-based chemicals, chlorine-based chemicals, etc. These descriptions of hazardous, toxic, and/or explosive chemicals conclude with a chapter on the identification of the inert chemicals, e.g. sand, used to fill practice munitions.« less

  4. Advanced Light Source Activity Report 2002

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Duque, Theresa; Greiner, Annette; Moxon, Elizabeth

    2003-06-12

    This annual report of the Advanced Light Source details science highlights and facility improvements during the year. It also offers information on events sponsored by the facility, technical specifications, and staff and publication information.

  5. Technical and Economic Evaluation of Advanced Air Cargo Systems

    NASA Technical Reports Server (NTRS)

    Whitehead, A. H., Jr.

    1978-01-01

    The current air cargo environment and the relevance of advanced technology aircraft in enhancing the efficiency of the 1990 air cargo system are discussed. NASA preliminary design studies are shown to indicate significant potential gains in aircraft efficiency and operational economics for future freighter concepts. Required research and technology elements are outlined to develop a better base for evaluating advanced design concepts. Current studies of the market operation are reviewed which will develop design criteria for a future dedicated cargo transport. Design features desirable in an all-freighter design are reviewed. NASA-sponsored studies of large, distributed-load freighters are reviewed and these designs are compared to current wide-body aircraft. These concepts vary in gross takeoff weight from 0.5 Gg (one million lbs.) to 1.5 Gg (three million lbs.) and are found to exhibit economic advantages over conventional design concepts.

  6. Technical writing versus technical writing

    NASA Technical Reports Server (NTRS)

    Dillingham, J. W.

    1981-01-01

    Two terms, two job categories, 'technical writer' and 'technical author' are discussed in terms of industrial and business requirements and standards. A distinction between 'technical writing' and technical 'writing' is made. The term 'technical editor' is also considered. Problems inherent in the design of programs to prepare and train students for these jobs are discussed. A closer alliance between industry and academia is suggested as a means of preparing students with competent technical communication skills (especially writing and editing skills) and good technical skills.

  7. 44 CFR 65.15 - List of communities submitting new technical data.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false List of communities... Program IDENTIFICATION AND MAPPING OF SPECIAL HAZARD AREAS § 65.15 List of communities submitting new technical data. This section provides a cumulative list of communities where modifications of the base flood...

  8. Identification of organic compounds in landfill leachate treated by advanced oxidation processes.

    PubMed

    Scandelai, Ana Paula Jambers; Sloboda Rigobello, Eliane; Oliveira, Beatriz Lopes Corso de; Tavares, Célia Regina Granhen

    2017-11-27

    Landfill leachates are considered to be complex effluents of a variable composition containing many biorecalcitrant and highly toxic compounds. Considering the shortage of studies concerning the treatment of landfill leachates using ozone, as well as its combination with catalysts, the aim of this paper was to identify the organic compounds in this effluent treated with advanced oxidation processes (AOPs) of ozonation (O 3 ), and heterogeneous catalytic ozonation with TiO 2 (O 3 /TiO 2 ) and with ZnO (O 3 /ZnO). In addition, this study sought to assess the efficiency of the removal of the organic matter present in the leachate. For the pre- and post-AOPs, the leachate was characterized through physicochemical parameters and identification of organic compounds using gas chromatography coupled to the mass spectrometry (GC-MS). The three processes studied (O 3 , O 3 /TiO 2 , and O 3 /ZnO) presented color removal, turbidity, BOD above 95%, and lower COD removals (19%, 24%, and 33%, respectively). All AOPs studied promoted a similar reduction of organic compounds from leachate, some of which with toxic and carcinogenic potential, such as p-cresol, bisphenol A, atrazine, and hexazinone. In addition, upon the removal of organic matter and organic compounds, the heterogeneous catalytic ozonation processes proved more efficient than the process carried out only with ozone.

  9. 40 CFR 52.1119 - Identification of plan-conditional approval.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Implementation Plan Revision for a Small Business Technical and Environmental Compliance Assistance Program dated... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Identification of plan-conditional... PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Massachusetts § 52.1119...

  10. Advanced solid-state NMR spectroscopy of natural organic matter.

    PubMed

    Mao, Jingdong; Cao, Xiaoyan; Olk, Dan C; Chu, Wenying; Schmidt-Rohr, Klaus

    2017-05-01

    Solid-state NMR is essential for the characterization of natural organic matter (NOM) and is gaining importance in geosciences and environmental sciences. This review is intended to highlight advanced solid-state NMR techniques, especially a systematic approach to NOM characterization, and their applications to the study of NOM. We discuss some basics of how to acquire high-quality and quantitative solid-state 13 C NMR spectra, and address some common technical mistakes that lead to unreliable spectra of NOM. The identification of specific functional groups in NOM, primarily based on 13 C spectral-editing techniques, is described and the theoretical background of some recently-developed spectral-editing techniques is provided. Applications of solid-state NMR to investigating nitrogen (N) in NOM are described, focusing on limitations of the widely used 15 N CP/MAS experiment and the potential of improved advanced NMR techniques for characterizing N forms in NOM. Then techniques used for identifying proximities, heterogeneities and domains are reviewed, and some examples provided. In addition, NMR techniques for studying segmental dynamics in NOM are reviewed. We also briefly discuss applications of solid-state NMR to NOM from various sources, including soil organic matter, aquatic organic matter, organic matter in atmospheric particulate matter, carbonaceous meteoritic organic matter, and fossil fuels. Finally, examples of NMR-based structural models and an outlook are provided. Copyright © 2016 Elsevier B.V. All rights reserved.

  11. NASA Advanced Supercomputing (NAS) User Services Group

    NASA Technical Reports Server (NTRS)

    Pandori, John; Hamilton, Chris; Niggley, C. E.; Parks, John W. (Technical Monitor)

    2002-01-01

    This viewgraph presentation provides an overview of NAS (NASA Advanced Supercomputing), its goals, and its mainframe computer assets. Also covered are its functions, including systems monitoring and technical support.

  12. Bibliography of Technical Publications and Papers, October 1978 - September 1979

    DTIC Science & Technology

    1979-11-01

    overnutrition. Symposium on Psychosocial Factors in Nutritional Problems, llth International Congress of Nutrition, Rio de Janeiro , Brazil, September...VBIOGRAPHY OF-TZHNICAL BLICATIONS AND An T7 Octber118 -Seu~imb~ 199k6. PERFORMNING OR0. REPORT NUMBER 7. AUTMOR( e ) S. CONTRACT -OR G ANT HNDMER~a) 9...Officer Advanced Class 79-2, US Army Quartermaster School, Fort Lee, VA, 14 August 1979. 6 OFFICE OF TECHNICAL DIRECTOR Technical Papers 12. ROSS, E . W

  13. Talent Identification and Development in Male Football: A Systematic Review.

    PubMed

    Sarmento, Hugo; Anguera, M Teresa; Pereira, Antonino; Araújo, Duarte

    2018-04-01

    Expertise has been extensively studied in several sports over recent years. The specificities of how excellence is achieved in Association Football, a sport practiced worldwide, are being repeatedly investigated by many researchers through a variety of approaches and scientific disciplines. The aim of this review was to identify and synthesise the most significant literature addressing talent identification and development in football. We identified the most frequently researched topics and characterised their methodologies. A systematic review of Web of Science™ Core Collection and Scopus databases was performed according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) guidelines. The following keywords were used: "football" and "soccer". Each word was associated with the terms "talent", "expert*", "elite", "elite athlete", "identification", "career transition" or "career progression". The selection was for the original articles in English containing relevant data about talent development/identification on male footballers. The search returned 2944 records. After screening against set criteria, a total of 70 manuscripts were fully reviewed. The quality of the evidence reviewed was generally excellent. The most common topics of analysis were (1) task constraints: (a) specificity and volume of practice; (2) performers' constraints: (a) psychological factors; (b) technical and tactical skills; (c) anthropometric and physiological factors; (3) environmental constraints: (a) relative age effect; (b) socio-cultural influences; and (4) multidimensional analysis. Results indicate that the most successful players present technical, tactical, anthropometric, physiological and psychological advantages that change non-linearly with age, maturational status and playing positions. These findings should be carefully considered by those involved in the identification and development of football players. This review highlights the need for coaches

  14. Identification of NAFTA-induced opportunities for Louisiana's ports and waterways : technical summary.

    DOT National Transportation Integrated Search

    1996-11-01

    This study identifies NAFTA-induced market opportunities for Louisianas maritime sector and to help define the strategies, maritime services, and port infrastructure requirements necessary to exploit these opportunities. Identification of current ...

  15. Establishment of the Center for Advanced Separation Technologies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Christopher E. Hull

    2006-09-30

    This Final Technical Report covers the eight sub-projects awarded in the first year and the five projects awarded in the second year of Cooperative Agreement DE-FC26-01NT41091: Establishment of the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

  16. Talent identification and recruitment in youth soccer: Recruiter's perceptions of the key attributes for player recruitment.

    PubMed

    Larkin, Paul; O'Connor, Donna

    2017-01-01

    Using the modified Delphi method, we aimed to understand the attributes youth coaches and recruiters perceive as important when identifying skilled youth performance at the entry level of representative soccer in Australia (i.e., Under 13 years). Furthermore, we also aimed to describe the current methods youth coaches and recruiters use to assess and identify these attributes in youth players. Australian regional youth technical directors and coaches (n = 20) completed a three stage process, including an initial interview and two subsequent questionnaires, whereby attributes and qualities associated with talent identification were rated and justified according to the importance for youth player performance and talent identification. Results indicate a hierarchy of attributes recruiters perceive as important for Under 13 soccer performance, including technical (i.e., first touch, striking the ball, one-versus-one ability, and technical ability under pressure), tactical (i.e., decision-making ability) and psychological attributes (i.e., coachability and positive attitude). In addition, the findings indicated attributes and qualities not emphasised within the talent identification process including, physiological, anthropometrical, sociological and several psychological attributes. It is suggested talent recruiters apply a holistic multidisciplinary approach to talent identification, with the current findings potentially providing initial evidence to suggest recruiters do consider numerous attributes when selecting and identifying youth players.

  17. TECHcitement: Advances in Technological Education.

    ERIC Educational Resources Information Center

    American Association of Community Colleges, Washington, DC.

    This publication includes seven articles. "ATE Grants Generate Life-Changing Experiences" discusses the National Science Foundation's (NSF) Advanced Technological Education (ATE) grants, which provide seed money and other support that community college educators use to enhance technical training and improve math and science instruction. "Phone…

  18. 40 CFR 52.1519 - Identification of plan-conditional approval.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Implementation Plan Revision for a Small Business Technical and Environmental compliance Assistance Program dated... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Identification of plan-conditional... PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) New Hampshire § 52.1519...

  19. [Study on the automatic parameters identification of water pipe network model].

    PubMed

    Jia, Hai-Feng; Zhao, Qi-Feng

    2010-01-01

    Based on the problems analysis on development and application of water pipe network model, the model parameters automatic identification is regarded as a kernel bottleneck of model's application in water supply enterprise. The methodology of water pipe network model parameters automatic identification based on GIS and SCADA database is proposed. Then the kernel algorithm of model parameters automatic identification is studied, RSA (Regionalized Sensitivity Analysis) is used for automatic recognition of sensitive parameters, and MCS (Monte-Carlo Sampling) is used for automatic identification of parameters, the detail technical route based on RSA and MCS is presented. The module of water pipe network model parameters automatic identification is developed. At last, selected a typical water pipe network as a case, the case study on water pipe network model parameters automatic identification is conducted and the satisfied results are achieved.

  20. In Fibrous Fields. Technics: Carpet for Architecture

    ERIC Educational Resources Information Center

    Yee, Roger

    1974-01-01

    Carpet is an ageless youth. Civilization has written its history on carpet. The architect specifying carpet for a wide range of applications soon learns it is technically as advanced as the buildings it graces. Tells story of art and craft of carpet manufacture from obscure origins in the Orient to modern manufacturing methods. (Author/EA)

  1. Printing/Graphic Arts Technology. Technical Committee Report.

    ERIC Educational Resources Information Center

    Idaho State Dept. of Education, Boise. Div. of Vocational Education.

    This Technical Committee Report prepared by industry representatives in Idaho lists the skills currently necessary for an employee in that state to obtain a job in printing and graphic arts technology, retain a job once hired, and advance in that occupational field. (Task lists are grouped according to duty areas generally used in industry…

  2. Nonparametric Identification of Causal Effects under Temporal Dependence

    ERIC Educational Resources Information Center

    Dafoe, Allan

    2018-01-01

    Social scientists routinely address temporal dependence by adopting a simple technical fix. However, the correct identification strategy for a causal effect depends on causal assumptions. These need to be explicated and justified; almost no studies do so. This article addresses this shortcoming by offering a precise general statement of the…

  3. Delivering Advanced Technical Education Using Online, Immersive Classroom Technology

    ERIC Educational Resources Information Center

    Smith, Delmer; Louwagie, Nancy

    2017-01-01

    Vacuum and thin film technologies are critical to advanced manufacturing industries. With a grant from the National Science Foundation (DUE #14004080), Normandale Community College has developed courses that are delivered online and via telepresence to provide a formal education to vacuum technician students around the country. Telepresence…

  4. Optical Automatic Car Identification (OACI) : Volume 1. Advanced System Specification.

    DOT National Transportation Integrated Search

    1978-12-01

    A performance specification is provided in this report for an Optical Automatic Car Identification (OACI) scanner system which features 6% improved readability over existing industry scanner systems. It also includes the analysis and rationale which ...

  5. Editing in Technical Communication: Theory and Practice in Editing Processes at the Graduate Level.

    ERIC Educational Resources Information Center

    Masse, Roger E.

    At New Mexico State University, technical communication teachers have developed a course to teach editing processes to graduate students who take the advanced workshop in technical and professional communication. In this seminar group, students work on writing processes; editing processes; written, edited, and tested products; and oral processes…

  6. Final Technical Report - Use of Systems Biology Approaches to Develop Advanced Biofuel-Synthesizing Cyanobacterial Strains

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pakrasi, Himadri

    The overall objective of this project was to use a systems biology approach to evaluate the potentials of a number of cyanobacterial strains for photobiological production of advanced biofuels and/or their chemical precursors. Cyanobacteria are oxygen evolving photosynthetic prokaryotes. Among them, certain unicellular species such as Cyanothece can also fix N 2, a process that is exquisitely sensitive to oxygen. To accommodate such incompatible processes in a single cell, Cyanothece produces oxygen during the day, and creates an O 2-limited intracellular environment during the night to perform O 2-sensitive processes such as N 2-fixation. Thus, Cyanothece cells are natural bioreactorsmore » for the storage of captured solar energy with subsequent utilization at a different time during a diurnal cycle. Our studies include the identification of a novel, fast-growing, mixotrophic, transformable cyanobacterium. This strain has been sequenced and will be made available to the community. In addition, we have developed genome-scale models for a family of cyanobacteria to assess their metabolic repertoire. Furthermore, we developed a method for rapid construction of metabolic models using multiple annotation sources and a metabolic model of a related organism. This method will allow rapid annotation and screening of potential phenotypes based on the newly available genome sequences of many organisms.« less

  7. Parameter identification studies on the NASA/Ames Research Center Advanced Concepts Flight Simulator. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Mckavitt, Thomas P., Jr.

    1990-01-01

    The results of an aircraft parameters identification study conducted on the National Aeronautics and Space Administration/Ames Research Center Advanced Concepts Flight Simulator (ACFS) in conjunction with the Navy-NASA Joint Institute of Aeronautics are given. The ACFS is a commercial airline simulator with a design based on future technology. The simulator is used as a laboratory for human factors research and engineering as applied to the commercial airline industry. Parametric areas examined were engine pressure ratio (EPR), optimum long range cruise Mach number, flap reference speed, and critical take-off speeds. Results were compared with corresponding parameters of the Boeing 757 and 767 aircraft. This comparison identified two areas where improvements can be made: (1) low maximum lift coefficients (on the order of 20-25 percent less than those of a 757); and (2) low optimum cruise Mach numbers. Recommendations were made to those anticipated with the application of future technologies.

  8. An analysis of the technical status of high level radioactive waste and spent fuel management systems

    NASA Technical Reports Server (NTRS)

    English, T.; Miller, C.; Bullard, E.; Campbell, R.; Chockie, A.; Divita, E.; Douthitt, C.; Edelson, E.; Lees, L.

    1977-01-01

    The technical status of the old U.S. mailine program for high level radioactive nuclear waste management, and the newly-developing program for disposal of unreprocessed spent fuel was assessed. The method of long term containment for both of these waste forms is considered to be deep geologic isolation in bedded salt. Each major component of both waste management systems is analyzed in terms of its scientific feasibility, technical achievability and engineering achievability. The resulting matrix leads to a systematic identification of major unresolved technical or scientific questions and/or gaps in these programs.

  9. Fundamentals of Dental Assisting. Technical Committee Report.

    ERIC Educational Resources Information Center

    Idaho State Dept. of Education, Boise. Div. of Vocational Education.

    This Technical Committee Report prepared by industry representatives in Idaho lists the skills currently necessary for an employee in that state to obtain a job in dental assisting, retain a job once hired, and advance in that occupational field. (Task lists are grouped according to duty areas generally used in industry settings, and are used as…

  10. Contact Us | OSTI, US Dept of Energy Office of Scientific and Technical

    Science.gov Websites

    Information skip to main content Sign In Create Account OSTI.GOV title logo U.S. Department of Energy Office of Scientific and Technical Information Search terms: Advanced search options Advanced Tools Public Access Policy Data Services & Dev Tools About FAQs News Sign In Create Account Contact

  11. Distinctive and Complementary MS2 Fragmentation Characteristics for Identification of Sulfated Sialylated N-Glycopeptides by nanoLC-MS/MS Workflow

    NASA Astrophysics Data System (ADS)

    Kuo, Chu-Wei; Guu, Shih-Yun; Khoo, Kay-Hooi

    2018-04-01

    High sensitivity identification of sulfated glycans carried on specific sites of glycoproteins is an important requisite for investigation of molecular recognition events involved in diverse biological processes. However, aiming for resolving site-specific glycosylation of sulfated glycopeptides by direct LC-MS2 sequencing is technically most challenging. Other than the usual limiting factors such as lower abundance and ionization efficiency compared to analysis of non-glycosylated peptides, confident identification of sulfated glycopeptides among the more abundant non-sulfated glycopeptides requires additional considerations in the selective enrichment and detection strategies. Metal oxide has been applied to enrich phosphopeptides and sialylated glycopeptides, but its use to capture sulfated glycopeptides has not been investigated. Likewise, various complementary MS2 fragmentation modes have yet to be tested against sialylated and non-sialylated sulfoglycopeptides due to limited appropriate sample availability. In this study, we have investigated the feasibility of sequencing tryptic sulfated N-glycopeptide and its MS2 fragmentation characteristics by first optimizing the enrichment methods to allow efficient LC-MS detection and MS2 analysis by a combination of CID, HCD, ETD, and EThcD on hybrid and tribrid Orbitrap instruments. Characteristic sulfated glyco-oxonium ions and direct loss of sulfite from precursors were detected as evidences of sulfate modification. It is anticipated that the technical advances demonstrated in this study would allow a feasible extension of our sulfoglycomic analysis to sulfoglycoproteomics. [Figure not available: see fulltext.

  12. Statewide Curriculum Articulation Project for Vocational-Technical Education in Minnesota. Final Report.

    ERIC Educational Resources Information Center

    Burger, Laura J.; And Others

    The goal of this project was to develop, validate, and utilize a process for vertically articulating curriculum between secondary and post secondary levels of vocational technical education throughout the state of Minnesota. Procedures involved the identification of two areas of staff responsibility: research and development, and service to local…

  13. Three dimensional identification card and applications

    NASA Astrophysics Data System (ADS)

    Zhou, Changhe; Wang, Shaoqing; Li, Chao; Li, Hao; Liu, Zhao

    2016-10-01

    Three dimensional Identification Card, with its three-dimensional personal image displayed and stored for personal identification, is supposed be the advanced version of the present two-dimensional identification card in the future [1]. Three dimensional Identification Card means that there are three-dimensional optical techniques are used, the personal image on ID card is displayed to be three-dimensional, so we can see three dimensional personal face. The ID card also stores the three-dimensional face information in its inside electronics chip, which might be recorded by using two-channel cameras, and it can be displayed in computer as three-dimensional images for personal identification. Three-dimensional ID card might be one interesting direction to update the present two-dimensional card in the future. Three-dimension ID card might be widely used in airport custom, entrance of hotel, school, university, as passport for on-line banking, registration of on-line game, etc...

  14. Advancing Humanities Studies at Community, Technical, and Junior Colleges.

    ERIC Educational Resources Information Center

    Eisenberg, Diane U.; And Others

    The American Association of Community and Junior Colleges' (AACJC's) two-year Advancing the Humanities Project (AHP) has assisted selected community colleges in promoting the humanities on their campuses. Parts I and II of this report on the AHP present statements by Dale Parnell and Judith Jeffrey Howard about the AACJC's humanities initiatives…

  15. Improved symbol rate identification method for on-off keying and advanced modulation format signals based on asynchronous delayed sampling

    NASA Astrophysics Data System (ADS)

    Cui, Sheng; Jin, Shang; Xia, Wenjuan; Ke, Changjian; Liu, Deming

    2015-11-01

    Symbol rate identification (SRI) based on asynchronous delayed sampling is accurate, cost-effective and robust to impairments. For on-off keying (OOK) signals the symbol rate can be derived from the periodicity of the second-order autocorrelation function (ACF2) of the delay tap samples. But it is found that when applied this method to advanced modulation format signals with auxiliary amplitude modulation (AAM), incorrect results may be produced because AAM has significant impact on ACF2 periodicity, which makes the symbol period harder or even unable to be correctly identified. In this paper it is demonstrated that for these signals the first order autocorrelation function (ACF1) has stronger periodicity and can be used to replace ACF2 to produce more accurate and robust results. Utilizing the characteristics of the ACFs, an improved SRI method is proposed to accommodate both OOK and advanced modulation formant signals in a transparent manner. Furthermore it is proposed that by minimizing the peak to average ratio (PAPR) of the delay tap samples with an additional tunable dispersion compensator (TDC) the limited dispersion tolerance can be expanded to desired values.

  16. Talent identification and recruitment in youth soccer: Recruiter’s perceptions of the key attributes for player recruitment

    PubMed Central

    2017-01-01

    Using the modified Delphi method, we aimed to understand the attributes youth coaches and recruiters perceive as important when identifying skilled youth performance at the entry level of representative soccer in Australia (i.e., Under 13 years). Furthermore, we also aimed to describe the current methods youth coaches and recruiters use to assess and identify these attributes in youth players. Australian regional youth technical directors and coaches (n = 20) completed a three stage process, including an initial interview and two subsequent questionnaires, whereby attributes and qualities associated with talent identification were rated and justified according to the importance for youth player performance and talent identification. Results indicate a hierarchy of attributes recruiters perceive as important for Under 13 soccer performance, including technical (i.e., first touch, striking the ball, one-versus-one ability, and technical ability under pressure), tactical (i.e., decision-making ability) and psychological attributes (i.e., coachability and positive attitude). In addition, the findings indicated attributes and qualities not emphasised within the talent identification process including, physiological, anthropometrical, sociological and several psychological attributes. It is suggested talent recruiters apply a holistic multidisciplinary approach to talent identification, with the current findings potentially providing initial evidence to suggest recruiters do consider numerous attributes when selecting and identifying youth players. PMID:28419175

  17. Technical Support Document: Development of the Advanced Energy Design Guide for Medium to Big Box Retail Buildings - 50% Energy Savings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bonnema, E.; Leach, M.; Pless, S.

    2013-06-01

    This Technical Support Document describes the process and methodology for the development of the Advanced Energy Design Guide for Medium to Big Box Retail Buildings: Achieving 50% Energy Savings Toward a Net Zero Energy Building (AEDG-MBBR) ASHRAE et al. (2011b). The AEDG-MBBR is intended to provide recommendations for achieving 50% whole-building energy savings in retail stores over levels achieved by following ANSI/ASHRAE/IESNA Standard 90.1-2004, Energy Standard for Buildings Except Low-Rise Residential Buildings (Standard 90.1-2004) (ASHRAE 2004b). The AEDG-MBBR was developed in collaboration with the American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE), the American Institute of Architects (AIA), themore » Illuminating Engineering Society of North America (IES), the U.S. Green Building Council (USGBC), and the U.S. Department of Energy.« less

  18. Technical Support Document: Development of the Advanced Energy Design Guide for Medium to Big Box Retail Buildings - 50% Energy Savings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bonnema, Eric; Leach, Matt; Pless, Shanti

    2013-06-05

    This Technical Support Document describes the process and methodology for the development of the Advanced Energy Design Guide for Medium to Big Box Retail Buildings: Achieving 50% Energy Savings Toward a Net Zero Energy Building (AEDG-MBBR) ASHRAE et al. (2011b). The AEDG-MBBR is intended to provide recommendations for achieving 50% whole-building energy savings in retail stores over levels achieved by following ANSI/ASHRAE/IESNA Standard 90.1-2004, Energy Standard for Buildings Except Low-Rise Residential Buildings (Standard 90.1-2004) (ASHRAE 2004b). The AEDG-MBBR was developed in collaboration with the American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE), the American Institute of Architects (AIA), themore » Illuminating Engineering Society of North America (IES), the U.S. Green Building Council (USGBC), and the U.S. Department of Energy.« less

  19. Technical specifications of low-frequency radio identification bedload tracking from field experiments: Differences in antennas, tags and operators

    NASA Astrophysics Data System (ADS)

    Arnaud, F.; Piégay, H.; Vaudor, L.; Bultingaire, L.; Fantino, G.

    2015-06-01

    Low-frequency passive integrated transponders (PIT tags) have been increasingly used for tracking bedload transport in gravel-bed rivers. Prior studies have reported high recovery rates in small streams, while recovery rates remained much lower in large systems, in large part because of the limited reading distance of the tags (< 1 m). Some laboratory tests have identified controlling factors for detection ranges (tag and antenna size, tag orientation, burial, submergence, etc.). Beyond these tests, improving our understanding of PIT tag functioning, using different equipment within different environments, is still needed in order to select the most suitable device for each geomorphic context. We address this knowledge gap with technical specifications for a low-frequency radio identification (RFID) device by working for the first time with real fluvial constraints, i.e., the gravel deposits and the aquatic channel. The three-dimensional detection envelopes of two types of tags and three types of antennas are quantified as well as the effect of practices (interoperator bias, battery power) on the detection. The interoperator variability and the intertag variability can be considered as negligible. The influence of burial in dry and water-saturated sediment and the influence of water immersion are shown to be minor. Finally, we summarize practical implications for RFID bedload tracking through these experiments.

  20. Using sentence combining in technical writing classes

    NASA Technical Reports Server (NTRS)

    Rosner, M.; Paul, T.

    1981-01-01

    Sentence combining exercises are advanced as a way to teach technical writing style without reliance upon abstractions, from which students do not learn. Such exercises: (1) give students regular writing practice; (2) teach the logic of sentence structure, sentence editing, and punctuation; (3) paragraph development and organization; and (4) rhetorical stance. Typical sentence, paragraph, and discourse level sentence combining exercises are described.

  1. Bringing Advanced Computational Techniques to Energy Research

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mitchell, Julie C

    2012-11-17

    Please find attached our final technical report for the BACTER Institute award. BACTER was created as a graduate and postdoctoral training program for the advancement of computational biology applied to questions of relevance to bioenergy research.

  2. Checker Takes the Guesswork out of Diode Identification

    ERIC Educational Resources Information Center

    Harman, Charles

    2011-01-01

    At technical colleges and secondary-level tech schools, students enrolled in basic electronics labs who have learned about diodes that do rectification are used to seeing power diodes like the 1N4001. When the students are introduced to low-power zener diodes and signal diodes, component identification gets more complex. If the small zeners are…

  3. Film in the Advanced Composition Classroom: A Tapestry of Style

    ERIC Educational Resources Information Center

    Durst, Pearce

    2015-01-01

    This article advances film as worthy of rhetorical inquiry and deserving of more sustained attention in the advanced composition classroom. The first section identifies various approaches to the "language" of film, which can be adopted to navigate the technical, rhetorical, and cultural concerns needed to compose informed multimodal…

  4. Advances in satellite oceanography

    NASA Technical Reports Server (NTRS)

    Brown, O. B.; Cheney, R. E.

    1983-01-01

    Technical advances and recent applications of active and passive satellite remote sensing techniques to the study of oceanic processes are summarized. The general themes include infrared and visible radiometry, active and passive microwave sensors, and buoy location systems. The surface parameters of sea surface temperature, windstream, sea state, altimetry, color, and ice are treated as applicable under each of the general methods.

  5. Crosscutting Technology Development at the Center for Advanced Separation Technologies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Christopher E. Hull

    2006-09-30

    This Technical Progress Report describes progress made on the twenty nine subprojects awarded in the second year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

  6. CROSSCUTTING TECHNOLOGY DEVELOPMENT AT THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Christopher E. Hull

    2006-05-15

    This Technical Progress Report describes progress made on the twenty nine subprojects awarded in the second year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

  7. Nonlinear system identification technique validation

    NASA Astrophysics Data System (ADS)

    Rudko, M.; Bussgang, J. J.

    1982-01-01

    This final technical report describes the results obtained by SIGNATRON, Inc. of Lexington MA on Air Force Contract F30602-80-C-0104 for Rome Air Development Center. The objective of this effort is to develop a technique for identifying system response of nonlinear circuits by measurements of output response to known inputs. The report describes results of a study into the system identification technique based on the pencil-of-function method previously explored by Jain (1974) and Ewen (1979). The procedure identified roles of the linear response and is intended as a first step in nonlinear response and is intended as a first step in nonlinear circuit identification. There are serious implementation problems associated with the original approach such as loss of accuracy due to repeated integrations, lack of good measures of accuracy and computational iteration to identify the number of poles.

  8. Advanced Solar Power Systems

    NASA Technical Reports Server (NTRS)

    Atkinson, J. H.; Hobgood, J. M.

    1984-01-01

    The Advanced Solar Power System (ASPS) concentrator uses a technically sophisticated design and extensive tooling to produce very efficient (80 to 90%) and versatile energy supply equipment which is inexpensive to manufacture and requires little maintenance. The advanced optical design has two 10th order, generalized aspheric surfaces in a Cassegrainian configuration which gives outstanding performance and is relatively insensitive to temperature changes and wind loading. Manufacturing tolerances also have been achieved. The key to the ASPS is the direct absorption of concentrated sunlight in the working fluid by radiative transfers in a black body cavity. The basic ASPS design concepts, efficiency, optical system, and tracking and focusing controls are described.

  9. National Coalition of Advanced Technology Centers Proposal to the Nation.

    ERIC Educational Resources Information Center

    National Coalition of Advanced Technology Centers, Waco, TX.

    In 1988, nine institutions operating advanced technology centers (ATC's) to provide workers with up-to-date technical skills formed the National Coalition of Advanced Technology Centers (NCATC). The center was established to increase awareness of ATC's, serve as a forum for the discussion and demonstration of new and underused technologies,…

  10. Fast and automatic thermographic material identification for the recycling process

    NASA Astrophysics Data System (ADS)

    Haferkamp, Heinz; Burmester, Ingo

    1998-03-01

    Within the framework of the future closed loop recycling process the automatic and economical sorting of plastics is a decisive element. The at the present time available identification and sorting systems are not yet suitable for the sorting of technical plastics since essential demands, as the realization of high recognition reliability and identification rates considering the variety of technical plastics, can not be guaranteed. Therefore the Laser Zentrum Hannover e.V. in cooperation with the Hoerotron GmbH and the Preussag Noell GmbH has carried out investigations on a rapid thermographic and laser-supported material- identification-system for automatic material-sorting- systems. The automatic identification of different engineering plastics coming from electronic or automotive waste is possible. Identification rates up to 10 parts per second are allowed by the effort from fast IR line scanners. The procedure is based on the following principle: within a few milliseconds a spot on the relevant sample is heated by a CO2 laser. The samples different and specific chemical and physical material properties cause different temperature distributions on their surfaces that are measured by a fast IR-linescan system. This 'thermal impulse response' has to be analyzed by means of a computer system. Investigations have shown that it is possible to analyze more than 18 different sorts of plastics at a frequency of 10 Hz. Crucial for the development of such a system is the rapid processing of imaging data, the minimization of interferences caused by oscillating samples geometries, and a wide range of possible additives in plastics in question. One possible application area is sorting of plastics coming from car- and electronic waste recycling.

  11. MO-FG-207-00: Technological Advances in PET/MR Imaging

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    2015-06-15

    The use of integrated PET/MRI systems in clinical applications can best benefit from understanding their technological advances and limitations. The currently available clinical PET/MRI systems have their own characteristics. Thorough analyses of existing technical data and evaluation of necessary performance metrics for quality assurances could be conducted to optimize application-specific PET/MRI protocols. This Symposium will focus on technical advances and limitations of clinical PET/MRI systems, and how this exciting imaging modality can be utilized in applications that can benefit from both PET and MRI. Learning Objectives: To understand the technological advances of clinical PET/MRI systems To correctly identify clinical applicationsmore » that can benefit from PET/MRI To understand ongoing work to further improve the current PET/MRI technology Floris Jansen is a GE Healthcare employee.« less

  12. Identification of the Key Fields and Their Key Technical Points of Oncology by Patent Analysis.

    PubMed

    Zhang, Ting; Chen, Juan; Jia, Xiaofeng

    2015-01-01

    This paper aims to identify the key fields and their key technical points of oncology by patent analysis. Patents of oncology applied from 2006 to 2012 were searched in the Thomson Innovation database. The key fields and their key technical points were determined by analyzing the Derwent Classification (DC) and the International Patent Classification (IPC), respectively. Patent applications in the top ten DC occupied 80% of all the patent applications of oncology, which were the ten fields of oncology to be analyzed. The number of patent applications in these ten fields of oncology was standardized based on patent applications of oncology from 2006 to 2012. For each field, standardization was conducted separately for each of the seven years (2006-2012) and the mean of the seven standardized values was calculated to reflect the relative amount of patent applications in that field; meanwhile, regression analysis using time (year) and the standardized values of patent applications in seven years (2006-2012) was conducted so as to evaluate the trend of patent applications in each field. Two-dimensional quadrant analysis, together with the professional knowledge of oncology, was taken into consideration in determining the key fields of oncology. The fields located in the quadrant with high relative amount or increasing trend of patent applications are identified as key ones. By using the same method, the key technical points in each key field were identified. Altogether 116,820 patents of oncology applied from 2006 to 2012 were retrieved, and four key fields with twenty-nine key technical points were identified, including "natural products and polymers" with nine key technical points, "fermentation industry" with twelve ones, "electrical medical equipment" with four ones, and "diagnosis, surgery" with four ones. The results of this study could provide guidance on the development direction of oncology, and also help researchers broaden innovative ideas and discover new

  13. A Technical Overview and Description of SOFIA (Stratospheric Observatory for Infrared Astronomy)

    NASA Technical Reports Server (NTRS)

    Kunz, Nans

    2003-01-01

    This paper provides a technical overview of SOFIA, a unique airborne observatory, from an engineering perspective. It will do this by describing several of the systems of this observatory that are common with mountain top ground based observatories but mostly emphasize those more unique features and systems that are required to facilitate world class astronomy from a highly modified Boeing 747-SP flying at Mach 0.84 in the Stratosphere. This paper provides a technical overview of SOFIA by reviewing each of the performance specifications (the level one requirements for development) and describing some of the technical advancements for the telescope as well as the platform required to achieve these performance specifications. The technical advancements involved include mirror technologies, control system features, the telescope suspension system, and the aircraft open port cavity with associated cavity door that opens in flight and tracks the telescope elevation angle. For background this paper will provide a brief programmatic overview of the SOFIA project including the joint project arrangement between the US and Germany (NASA and DLR). Additionally, this paper will describe the up to date status of the development of SOFIA as the Observatory nears the date of the first test flight in the summer of 2004.

  14. TECHcitement: Advances in Technological Education, 2006

    ERIC Educational Resources Information Center

    American Association of Community Colleges (NJ1), 2006

    2006-01-01

    This publication includes 13 articles: (1) ATE [Advanced Technological Education] Attuned to Global Competition; (2) Materials Science Center Supplies Information on Often-Overlooked Field; (3) CSEC [Cyber Security Education Consortium] Builds Corps of Cyber Technicians; (4) KCTCS [Kentucky Community and Technical College System] Is U.S. Partner…

  15. Esophageal motor function: technical aspects of manometry.

    PubMed

    Gyawali, C Prakash; Patel, Amit

    2014-10-01

    High-resolution manometry (HRM) has advanced the understanding of esophageal peristaltic mechanisms and has simplified esophageal motor testing. In this article the technical aspects of HRM are addressed, focusing on test protocols, in addition to concerns and pitfalls in performing esophageal motor studies. Specifically, catheter positioning, equipment-related artifacts, basal data acquisition, adequate swallows, and provocative maneuvers are discussed. Copyright © 2014 Elsevier Inc. All rights reserved.

  16. National Alliance for Advanced Biofuels and Bio-Products Final Technical Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Olivares, Jose A.; Baxter, Ivan; Brown, Judith

    2014-09-30

    The main objective of NAABB was to combine science, technology, and engineering expertise from across the nation to break down critical technical barriers to commercialization of algae-based biofuels. The approach was to address technology development across the entire value chain of algal biofuels production, from selection of strains to cultivation, harvesting, extraction, fuel conversion, and agricultural coproduct production. Sustainable practices and financial feasibility assessments ununderscored the approach and drove the technology development.

  17. Consensus Recommendations for Advancing Breast Cancer: Risk Identification and Screening in Ethnically Diverse Younger Women

    PubMed Central

    Stojadinovic, Alexander; Summers, Thomas A; Eberhardt, John; Cerussi, Albert; Grundfest, Warren; Peterson, Charles M.; Brazaitis, Michael; Krupinski, Elizabeth; Freeman, Harold

    2011-01-01

    A need exists for a breast cancer risk identification paradigm that utilizes relevant demographic, clinical, and other readily obtainable patient-specific data in order to provide individualized cancer risk assessment, direct screening efforts, and detect breast cancer at an early disease stage in historically underserved populations, such as younger women (under age 40) and minority populations, who represent a disproportionate number of military beneficiaries. Recognizing this unique need for military beneficiaries, a consensus panel was convened by the USA TATRC to review available evidence for individualized breast cancer risk assessment and screening in young (< 40), ethnically diverse women with an overall goal of improving care for military beneficiaries. In the process of review and discussion, it was determined to publish our findings as the panel believes that our recommendations have the potential to reduce health disparities in risk assessment, health promotion, disease prevention, and early cancer detection within and in other underserved populations outside of the military. This paper aims to provide clinicians with an overview of the clinical factors, evidence and recommendations that are being used to advance risk assessment and screening for breast cancer in the military. PMID:21509152

  18. DAFi: A directed recursive data filtering and clustering approach for improving and interpreting data clustering identification of cell populations from polychromatic flow cytometry data.

    PubMed

    Lee, Alexandra J; Chang, Ivan; Burel, Julie G; Lindestam Arlehamn, Cecilia S; Mandava, Aishwarya; Weiskopf, Daniela; Peters, Bjoern; Sette, Alessandro; Scheuermann, Richard H; Qian, Yu

    2018-04-17

    Computational methods for identification of cell populations from polychromatic flow cytometry data are changing the paradigm of cytometry bioinformatics. Data clustering is the most common computational approach to unsupervised identification of cell populations from multidimensional cytometry data. However, interpretation of the identified data clusters is labor-intensive. Certain types of user-defined cell populations are also difficult to identify by fully automated data clustering analysis. Both are roadblocks before a cytometry lab can adopt the data clustering approach for cell population identification in routine use. We found that combining recursive data filtering and clustering with constraints converted from the user manual gating strategy can effectively address these two issues. We named this new approach DAFi: Directed Automated Filtering and Identification of cell populations. Design of DAFi preserves the data-driven characteristics of unsupervised clustering for identifying novel cell subsets, but also makes the results interpretable to experimental scientists through mapping and merging the multidimensional data clusters into the user-defined two-dimensional gating hierarchy. The recursive data filtering process in DAFi helped identify small data clusters which are otherwise difficult to resolve by a single run of the data clustering method due to the statistical interference of the irrelevant major clusters. Our experiment results showed that the proportions of the cell populations identified by DAFi, while being consistent with those by expert centralized manual gating, have smaller technical variances across samples than those from individual manual gating analysis and the nonrecursive data clustering analysis. Compared with manual gating segregation, DAFi-identified cell populations avoided the abrupt cut-offs on the boundaries. DAFi has been implemented to be used with multiple data clustering methods including K-means, FLOCK, FlowSOM, and

  19. Repeatability and Reproducibility in Proteomic Identifications by Liquid Chromatography—Tandem Mass Spectrometry

    PubMed Central

    Tabb, David L.; Vega-Montoto, Lorenzo; Rudnick, Paul A.; Variyath, Asokan Mulayath; Ham, Amy-Joan L.; Bunk, David M.; Kilpatrick, Lisa E.; Billheimer, Dean D.; Blackman, Ronald K.; Cardasis, Helene L.; Carr, Steven A.; Clauser, Karl R.; Jaffe, Jacob D.; Kowalski, Kevin A.; Neubert, Thomas A.; Regnier, Fred E.; Schilling, Birgit; Tegeler, Tony J.; Wang, Mu; Wang, Pei; Whiteaker, Jeffrey R.; Zimmerman, Lisa J.; Fisher, Susan J.; Gibson, Bradford W.; Kinsinger, Christopher R.; Mesri, Mehdi; Rodriguez, Henry; Stein, Steven E.; Tempst, Paul; Paulovich, Amanda G.; Liebler, Daniel C.; Spiegelman, Cliff

    2009-01-01

    The complexity of proteomic instrumentation for LC-MS/MS introduces many possible sources of variability. Data-dependent sampling of peptides constitutes a stochastic element at the heart of discovery proteomics. Although this variation impacts the identification of peptides, proteomic identifications are far from completely random. In this study, we analyzed interlaboratory data sets from the NCI Clinical Proteomic Technology Assessment for Cancer to examine repeatability and reproducibility in peptide and protein identifications. Included data spanned 144 LC-MS/MS experiments on four Thermo LTQ and four Orbitrap instruments. Samples included yeast lysate, the NCI-20 defined dynamic range protein mix, and the Sigma UPS 1 defined equimolar protein mix. Some of our findings reinforced conventional wisdom, such as repeatability and reproducibility being higher for proteins than for peptides. Most lessons from the data, however, were more subtle. Orbitraps proved capable of higher repeatability and reproducibility, but aberrant performance occasionally erased these gains. Even the simplest protein digestions yielded more peptide ions than LC-MS/MS could identify during a single experiment. We observed that peptide lists from pairs of technical replicates overlapped by 35–60%, giving a range for peptide-level repeatability in these experiments. Sample complexity did not appear to affect peptide identification repeatability, even as numbers of identified spectra changed by an order of magnitude. Statistical analysis of protein spectral counts revealed greater stability across technical replicates for Orbitraps, making them superior to LTQ instruments for biomarker candidate discovery. The most repeatable peptides were those corresponding to conventional tryptic cleavage sites, those that produced intense MS signals, and those that resulted from proteins generating many distinct peptides. Reproducibility among different instruments of the same type lagged behind

  20. An Advanced Platform for Biomolecular Detection and Analysis Systems

    DTIC Science & Technology

    2005-02-01

    AFRL-IF-RS-TR-2005-54 Final Technical Report February 2005 AN ADVANCED PLATFORM FOR BIOMOLECULAR DETECTION AND ANALYSIS SYSTEMS...SUBTITLE AN ADVANCED PLATFORM FOR BIOMOLECULAR DETECTION AND ANALYSIS SYSTEMS 6. AUTHOR(S) David J. Beebe 5. FUNDING NUMBERS G...detection, analysis and response as well as many non BC warfare applications such as environmental toxicology, clinical detection and diagnosis

  1. Potentials of Advanced Database Technology for Military Information Systems

    DTIC Science & Technology

    2001-04-01

    UNCLASSIFIED Defense Technical Information Center Compilation Part Notice ADP010866 TITLE: Potentials of Advanced Database Technology for Military... Technology for Military Information Systems Sunil Choennia Ben Bruggemanb a National Aerospace Laboratory, NLR, P.O. Box 90502, 1006 BM Amsterdam...application of advanced information tech- nology, including database technology , as underpin- actions X and Y as dangerous or not? ning is

  2. CONTACT: An Air Force technical report on military satellite control technology

    NASA Astrophysics Data System (ADS)

    Weakley, Christopher K.

    1993-07-01

    This technical report focuses on Military Satellite Control Technologies and their application to the Air Force Satellite Control Network (AFSCN). This report is a compilation of articles that provide an overview of the AFSCN and the Advanced Technology Program, and discusses relevant technical issues and developments applicable to the AFSCN. Among the topics covered are articles on Future Technology Projections; Future AFSCN Topologies; Modeling of the AFSCN; Wide Area Communications Technology Evolution; Automating AFSCN Resource Scheduling; Health & Status Monitoring at Remote Tracking Stations; Software Metrics and Tools for Measuring AFSCN Software Performance; Human-Computer Interface Working Group; Trusted Systems Workshop; and the University Technical Interaction Program. In addition, Key Technology Area points of contact are listed in the report.

  3. MALDI-TOF MS Profiling-Advances in Species Identification of Pests, Parasites, and Vectors.

    PubMed

    Murugaiyan, Jayaseelan; Roesler, Uwe

    2017-01-01

    Invertebrate pests and parasites of humans, animals, and plants continue to cause serious diseases and remain as a high treat to agricultural productivity and storage. The rapid and accurate species identification of the pests and parasites are needed for understanding epidemiology, monitoring outbreaks, and designing control measures. Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) profiling has emerged as a rapid, cost effective, and high throughput technique of microbial species identification in modern diagnostic laboratories. The development of soft ionization techniques and the release of commercial pattern matching software platforms has resulted in the exponential growth of applications in higher organisms including parasitology. The present review discusses the proof-of-principle experiments and various methods of MALDI MS profiling in rapid species identification of both laboratory and field isolates of pests, parasites and vectors.

  4. MALDI-TOF MS Profiling-Advances in Species Identification of Pests, Parasites, and Vectors

    PubMed Central

    Murugaiyan, Jayaseelan; Roesler, Uwe

    2017-01-01

    Invertebrate pests and parasites of humans, animals, and plants continue to cause serious diseases and remain as a high treat to agricultural productivity and storage. The rapid and accurate species identification of the pests and parasites are needed for understanding epidemiology, monitoring outbreaks, and designing control measures. Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) profiling has emerged as a rapid, cost effective, and high throughput technique of microbial species identification in modern diagnostic laboratories. The development of soft ionization techniques and the release of commercial pattern matching software platforms has resulted in the exponential growth of applications in higher organisms including parasitology. The present review discusses the proof-of-principle experiments and various methods of MALDI MS profiling in rapid species identification of both laboratory and field isolates of pests, parasites and vectors. PMID:28555175

  5. The NASA Advanced Space Power Systems Project

    NASA Technical Reports Server (NTRS)

    Mercer, Carolyn R.; Hoberecht, Mark A.; Bennett, William R.; Lvovich, Vadim F.; Bugga, Ratnakumar

    2015-01-01

    The goal of the NASA Advanced Space Power Systems Project is to develop advanced, game changing technologies that will provide future NASA space exploration missions with safe, reliable, light weight and compact power generation and energy storage systems. The development effort is focused on maturing the technologies from a technology readiness level of approximately 23 to approximately 56 as defined in the NASA Procedural Requirement 7123.1B. Currently, the project is working on two critical technology areas: High specific energy batteries, and regenerative fuel cell systems with passive fluid management. Examples of target applications for these technologies are: extending the duration of extravehicular activities (EVA) with high specific energy and energy density batteries; providing reliable, long-life power for rovers with passive fuel cell and regenerative fuel cell systems that enable reduced system complexity. Recent results from the high energy battery and regenerative fuel cell technology development efforts will be presented. The technical approach, the key performance parameters and the technical results achieved to date in each of these new elements will be included. The Advanced Space Power Systems Project is part of the Game Changing Development Program under NASAs Space Technology Mission Directorate.

  6. Advanced Exploration Systems Atmosphere Resource Recovery and Environmental Monitoring

    NASA Technical Reports Server (NTRS)

    Perry, J.; Abney, M.; Conrad, R.; Garber, A.; Howard, D.; Kayatin, M.; Knox, J.; Newton, R.; Parrish, K.; Roman, M.; hide

    2016-01-01

    In September 2011, the Atmosphere Resource Recovery and Environmental Monitoring (ARREM) project was commissioned by NASA's Advanced Exploration Systems program to advance Atmosphere Revitalization Subsystem (ARS) and Environmental Monitoring Subsystem (EMS) technologies for enabling future crewed space exploration missions beyond low Earth orbit. The ARREM project's period of performance covered U.S. Government fiscal years 2012-2014. The ARREM project critically assessed the International Space Station (ISS) ARS and EMS architectures and process technologies as the foundation for an architecture suitable for deep space exploration vehicles. The project's technical content included technical tasks focused on improving the reliability and life cycle cost of ARS and EMS technologies as well as reducing future flight project developmental risk and design, development, test, and evaluation costs. Targeted technology development and maturation tasks, including key technical trade assessments, were accomplished and integrated ARS architectures were demonstrated. The ARREM project developed, demonstrated, and tested leading process technology candidates and subsystem architectures that met or exceeded key figures of merit, addressed capability gaps, and significantly improved the efficiency, safety, and reliability over the state-of-the-art ISS figures of merit. Promising EMS instruments were developed and functionally demonstrated in a simulated cabin environment. The project's technical approach and results are described and recommendations for continued development are provided.

  7. Identification of the Key Fields and Their Key Technical Points of Oncology by Patent Analysis

    PubMed Central

    Zhang, Ting; Chen, Juan; Jia, Xiaofeng

    2015-01-01

    Background This paper aims to identify the key fields and their key technical points of oncology by patent analysis. Methodology/Principal Findings Patents of oncology applied from 2006 to 2012 were searched in the Thomson Innovation database. The key fields and their key technical points were determined by analyzing the Derwent Classification (DC) and the International Patent Classification (IPC), respectively. Patent applications in the top ten DC occupied 80% of all the patent applications of oncology, which were the ten fields of oncology to be analyzed. The number of patent applications in these ten fields of oncology was standardized based on patent applications of oncology from 2006 to 2012. For each field, standardization was conducted separately for each of the seven years (2006–2012) and the mean of the seven standardized values was calculated to reflect the relative amount of patent applications in that field; meanwhile, regression analysis using time (year) and the standardized values of patent applications in seven years (2006–2012) was conducted so as to evaluate the trend of patent applications in each field. Two-dimensional quadrant analysis, together with the professional knowledge of oncology, was taken into consideration in determining the key fields of oncology. The fields located in the quadrant with high relative amount or increasing trend of patent applications are identified as key ones. By using the same method, the key technical points in each key field were identified. Altogether 116,820 patents of oncology applied from 2006 to 2012 were retrieved, and four key fields with twenty-nine key technical points were identified, including “natural products and polymers” with nine key technical points, “fermentation industry” with twelve ones, “electrical medical equipment” with four ones, and “diagnosis, surgery” with four ones. Conclusions/Significance The results of this study could provide guidance on the development

  8. Advanced information society(5)

    NASA Astrophysics Data System (ADS)

    Tanizawa, Ippei

    Based on the advancement of information network technology information communication forms informationalized society giving significant impact on business activities and life style in it. The information network has been backed up technologically by development of computer technology and has got great contribution by enhanced computer technology and communication equipments. Information is transferred by digital and analog methods. Technical development which has brought out multifunctioned modems of communication equipments in analog mode, and construction of advanced information communication network which has come out by joint work of computer and communication under digital technique, are described. The trend in institutional matter and standardization of electrical communication is also described showing some examples of value-added network (VAN).

  9. Technical variations in low-input RNA-seq methodologies.

    PubMed

    Bhargava, Vipul; Head, Steven R; Ordoukhanian, Phillip; Mercola, Mark; Subramaniam, Shankar

    2014-01-14

    Recent advances in RNA-seq methodologies from limiting amounts of mRNA have facilitated the characterization of rare cell-types in various biological systems. So far, however, technical variations in these methods have not been adequately characterized, vis-à-vis sensitivity, starting with reduced levels of mRNA. Here, we generated sequencing libraries from limiting amounts of mRNA using three amplification-based methods, viz. Smart-seq, DP-seq and CEL-seq, and demonstrated significant technical variations in these libraries. Reduction in mRNA levels led to inefficient amplification of the majority of low to moderately expressed transcripts. Furthermore, noise in primer hybridization and/or enzyme incorporation was magnified during the amplification step resulting in significant distortions in fold changes of the transcripts. Consequently, the majority of the differentially expressed transcripts identified were either high-expressed and/or exhibited high fold changes. High technical variations ultimately masked subtle biological differences mandating the development of improved amplification-based strategies for quantitative transcriptomics from limiting amounts of mRNA.

  10. Workforce Development: Employment Retention and Advancement Under TANF. Technical Paper.

    ERIC Educational Resources Information Center

    Patel, Nisha

    In this report, employment retention and advancement under Temporary Assistance for Needy Families (TANF) was examined by reviewing research findings regarding labor market development since 1996. According to the research, most of those moving from welfare to work have found employment in low-wage jobs and experienced frequent job losses and…

  11. MentorLinks: Advancing Technological Education, 2008-2010

    ERIC Educational Resources Information Center

    Hause, Ellen M., Ed.

    2010-01-01

    MentorLinks, part of the Advancing Technological Education program supported by the National Science Foundation and administered by the American Association of Community Colleges (AACC), provides technical assistance and networking opportunities to improve community college programs that prepare technicians in the science, technology, engineering,…

  12. Strategies for target identification of antimicrobial natural products.

    PubMed

    Farha, Maya A; Brown, Eric D

    2016-05-04

    Covering: 2000 to 2015Despite a pervasive decline in natural product research at many pharmaceutical companies over the last two decades, natural products have undeniably been a prolific and unsurpassed source for new lead antibacterial compounds. Due to their inherent complexity, natural extracts face several hurdles in high-throughout discovery programs, including target identification. Target identification and validation is a crucial process for advancing hits through the discovery pipeline, but has remained a major bottleneck. In the case of natural products, extremely low yields and limited compound supply further impede the process. Here, we review the wealth of target identification strategies that have been proposed and implemented for the characterization of novel antibacterials. Traditionally, these have included genomic and biochemical-based approaches, which, in recent years, have been improved with modern-day technology and better honed for natural product discovery. Further, we discuss the more recent innovative approaches for uncovering the target of new antibacterial natural products, which have resulted from modern advances in chemical biology tools. Finally, we present unique screening platforms implemented to streamline the process of target identification. The different innovative methods to respond to the challenge of characterizing the mode of action for antibacterial natural products have cumulatively built useful frameworks that may advocate a renovated interest in natural product drug discovery programs.

  13. In vitro evaluation of a passive radio frequency identification microchip implanted in human molars subjected to compression forces, for forensic purposes of human identification

    PubMed Central

    Moreno, Freddy; Vallejo, Diego; Garzón, Herney; Moreno, Sandra

    2013-01-01

    Objective: To evaluate the in vitro behavior of a passive Radio Frequency Identification (RFID) microchip implanted in human molars subjected to compression forces to determine its technical and clinical viability. Materials and Methods: In vitro experimental study to evaluate the physical behavior of a passive RFID microchip (VeriChip™) implanted in human molars through resin restoration (Filtek P90™ Silorane 3M-ESPE®) to determine the clinical and technical possibilities of the implant and the viability to withstand compression forces exerted by the stomatognathic system during mastication. Results: Through the ANOVA test, it was found that the teeth on which a microchip was implanted show great resistance to compressive forces. It was also evident that teeth with microchips implanted in Class V cavities are more resistant than those implanted in Class I cavities. Conclusions: Although microchip dimensions are big, requiring a sufficiently large cavity, from the biomechanical point of view it is plausible to implant a microchip in a Class V cavity employing restoration material based on resin for forensic purposes of human identification. PMID:24255554

  14. Laparoscopic splenic hilar lymphadenectomy for advanced gastric cancer.

    PubMed

    Hosogi, Hisahiro; Okabe, Hiroshi; Shinohara, Hisashi; Tsunoda, Shigeru; Hisamori, Shigeo; Sakai, Yoshiharu

    2016-01-01

    Laparoscopic distal gastrectomy has recently become accepted as a surgical option for early gastric cancer in the distal stomach, but laparoscopic total gastrectomy (LTG) has not become widespread because of technical difficulties of esophagojejunal anastomosis and splenic hilar lymphadenectomy. Splenic hilar lymphadenectomy should be employed in the treatment of advanced proximal gastric cancer to complete D2 dissection, but laparoscopically it is technically difficult even for skilled surgeons. Based on the evidence that prophylactic combined resection of spleen in total gastrectomy increased the risk of postoperative morbidity with no survival impact, surgeons have preferred laparoscopic spleen-preserving splenic hilar lymphadenectomy (LSPL) for advanced tumors without metastasis to splenic hilar nodes or invasion to the greater curvature of the stomach, and reports with LSPL have been increasing rather than LTG with splenectomy. In this paper, recent reports with laparoscopic splenic hilar lymphadenectomy were reviewed.

  15. Status of the Advanced Virgo gravitational wave detector

    NASA Astrophysics Data System (ADS)

    Acernese, F.; Adams, T.; Agatsuma, K.; Aiello, L.; Allocca, A.; Amato, A.; Antier, S.; Arnaud, N.; Ascenzi, S.; Astone, P.; Bacon, P.; Bader, M. K. M.; Baldaccini, F.; Ballardin, G.; Barone, F.; Barsuglia, M.; Barta, D.; Basti, A.; Bawaj, M.; Bazzan, M.; Bejger, M.; Belahcene, I.; Bersanetti, D.; Bertolini, A.; Bitossi, M.; Bizouard, M. A.; Bloemen, S.; Boer, M.; Bogaert, G.; Bondu, F.; Bonnand, R.; Boom, B. A.; Boschi, V.; Bouffanais, Y.; Bozzi, A.; Bradaschia, C.; Branchesi, M.; Briant, T.; Brillet, A.; Brisson, V.; Bulik, T.; Bulten, H. J.; Buskulic, D.; Buy, C.; Cagnoli, G.; Calloni, E.; Canepa, M.; Canizares, P.; Capocasa, E.; Carbognani, F.; Casanueva Diaz, J.; Casentini, C.; Cavalier, F.; Cavalieri, R.; Cella, G.; Cerboni Baiardi, L.; Cerretani, G.; Cesarini, E.; Chassande-Mottin, E.; Chincarini, A.; Chiummo, A.; Christensen, N.; Chua, S.; Ciolfi, R.; Cirone, A.; Cleva, F.; Coccia, E.; Cohadon, P.-F.; Colla, A.; Conti, L.; Cortese, S.; Coulon, J.-P.; Cuoco, E.; D'Antonio, S.; Dattilo, V.; Davier, M.; Degallaix, J.; de Laurentis, M.; Deléglise, S.; Del Pozzo, W.; De Rosa, R.; di Fiore, L.; di Giovanni, M.; di Girolamo, T.; di Lieto, A.; di Pace, S.; di Palma, I.; di Renzo, F.; Dolique, V.; Ducrot, M.; Fafone, V.; Farinon, S.; Ferrante, I.; Ferrini, F.; Fidecaro, F.; Fiori, I.; Fiorucci, D.; Flaminio, R.; Fournier, J.-D.; Frasca, S.; Frasconi, F.; Frey, V.; Gammaitoni, L.; Garufi, F.; Gemme, G.; Genin, E.; Gennai, A.; Germain, V.; Ghosh, A.; Ghosh, S.; Giazotto, A.; Gonzalez Castro, J. M.; Gosselin, M.; Gouaty, R.; Grado, A.; Granata, M.; Greco, G.; Groot, P.; Gruning, P.; Guidi, G. M.; Harms, J.; Heidmann, A.; Heitmann, H.; Hello, P.; Hemming, G.; Hoak, D.; Hofman, D.; Huet, D.; Intini, G.; Isac, J.-M.; Jacqmin, T.; Jaranowski, P.; Jonker, R. J. G.; Kéfélian, F.; Khan, I.; Koley, S.; Kowalska, I.; Królak, A.; Kutynia, A.; Lartaux-Vollard, A.; Lazzaro, C.; Leaci, P.; Leonardi, M.; Leroy, N.; Letendre, N.; Lorenzini, M.; Loriette, V.; Losurdo, G.; Lumaca, D.; Majorana, E.; Maksimovic, I.; Man, N.; Mantovani, M.; Marchesoni, F.; Marion, F.; Martelli, F.; Martellini, L.; Masserot, A.; Mastrogiovanni, S.; Meidam, J.; Merzougui, M.; Metzdorff, R.; Mezzani, F.; Michel, C.; Milano, L.; Miller, A.; Minazzoli, O.; Minenkov, Y.; Moggi, A.; Mohan, M.; Montani, M.; Mours, B.; Nardecchia, I.; Naticchioni, L.; Nelemans, G.; Neri, M.; Nichols, D.; Nissanke, S.; Nocera, F.; Palomba, C.; Paoletti, F.; Paoli, A.; Pasqualetti, A.; Passaquieti, R.; Passuello, D.; Patricelli, B.; Pedurand, R.; Perreca, A.; Piccinni, O. J.; Pichot, M.; Piergiovanni, F.; Pillant, G.; Pinard, L.; Poggiani, R.; Popolizio, P.; Porter, E. K.; Prodi, G. A.; Punturo, M.; Puppo, P.; Rapagnani, P.; Razzano, M.; Regimbau, T.; Rei, L.; Ricci, F.; Robinet, F.; Rocchi, A.; Rolland, L.; Romano, R.; Rosińska, D.; Ruggi, P.; Salconi, L.; Sassolas, B.; Schmidt, P.; Sentenac, D.; Sequino, V.; Sieniawska, M.; Singhal, A.; Sorrentino, F.; Stratta, G.; Swinkels, B. L.; Tacca, M.; Tiwari, S.; Tonelli, M.; Travasso, F.; Tringali, M. C.; Trozzo, L.; Tsang, K. W.; van Bakel, N.; van Beuzekom, M.; van den Brand, J. F. J.; van den Broeck, C.; van der Schaaf, L.; van Heijningen, J. V.; Vardaro, M.; Vasúth, M.; Vedovato, G.; Verkindt, D.; Vetrano, F.; Viceré, A.; Vinet, J.-Y.; Vocca, H.; Walet, R.; Wang, G.; Was, M.; Yvert, M.; Zadrożny, A.; Zelenova, T.; Zendri, J.-P.

    2017-10-01

    Advanced Virgo is the French-Italian second generation laser gravitational wave detector, successor of the Initial Virgo. This new interferometer keeps only the infrastructure of its predecessor and aims to be ten times more sensitive, with its first science run planned for 2017. This article gives an overview of the Advanced Virgo design and the technical choices behind it. Finally, the up-to-date progresses and the planned upgrade for the following years are detailed.

  16. Advanced technology and future earth-orbit transportation systems

    NASA Technical Reports Server (NTRS)

    Henry, B. Z.; Eldred, C. H.

    1977-01-01

    The paper is concerned with the identification and evaluation of technology developments which offer potential for high return on investment when applied to advanced transportation systems. These procedures are applied in a study of winged single-stage-to-orbit (SSTO) vehicles, which are considered feasible by the 1990s. Advanced technology is considered a key element in achieving improved economics, and near term investment in selected technology areas is recommended.

  17. Advanced driver assistance system: Road sign identification using VIAPIX system and a correlation technique

    NASA Astrophysics Data System (ADS)

    Ouerhani, Y.; Alfalou, A.; Desthieux, M.; Brosseau, C.

    2017-02-01

    We present a three-step approach based on the commercial VIAPIX® module for road traffic sign recognition and identification. Firstly, detection in a scene of all objects having characteristics of traffic signs is performed. This is followed by a first-level recognition based on correlation which consists in making a comparison between each detected object with a set of reference images of a database. Finally, a second level of identification allows us to confirm or correct the previous identification. In this study, we perform a correlation-based analysis by combining and adapting the Vander Lugt correlator with the nonlinear joint transformation correlator (JTC). Of particular significance, this approach permits to make a reliable decision on road traffic sign identification. We further discuss a robust scheme allowing us to track a detected road traffic sign in a video sequence for the purpose of increasing the decision performance of our system. This approach can have broad practical applications in the maintenance and rehabilitation of transportation infrastructure, or for drive assistance.

  18. Utah's 1988-93 Vocational-Technical Education Master Plan: A Powerful Resource for Human and Economic Development.

    ERIC Educational Resources Information Center

    Utah State Board of Higher Education, Salt Lake City.

    For Utah residents to remain in the forefront or even stay competitive economically, the state's work force must acquire the knowledge and skills that match or exceed those of their most technically advanced competitors. A powerful engine for economic growth is a high-quality system of vocational-technical education. The majority of Utah public…

  19. Advanced Teleprocessing Systems

    DTIC Science & Technology

    1983-09-30

    Defenae AdTanced Research Projects Agency DAHC1S.C0368 DARPA rw M n*~ MDA 903.77.C-0272 A ^^ ^ 2490 MDA «)W3-C-0064 COMPUTER NETWORK...i -.% W-V."’ * - \\ ATV.VVV" ir*7 ADVANCED TELEPROCESSING SYSTEMS Semi-Annual Technical Report September 30, 1983 Contract Number: MDA 903-82...83 through 30 SEPT 83 6 PERFORMING ORG. REPORT NUMBER 7. AUTHORC«; Leonard Kleinrock 8 CONTRACT OR GRANT NUMBERr«; MDA 903-82-C-0064 9

  20. MentorLinks: Advancing Technological Education, 2005-2007

    ERIC Educational Resources Information Center

    Hause, Ellen M., Ed.

    2008-01-01

    The goals of the MentorLinks: Advancing Technological Education program, supported by the National Science Foundation and administered by the American Association of Community Colleges (AACC), are to provide technical assistance and networking opportunities for the purpose of improving community college programs that prepare technicians in the…

  1. Recreational technical diving part 1: an introduction to technical diving methods and activities.

    PubMed

    Mitchell, Simon J; Doolette, David J

    2013-06-01

    Technical divers use gases other than air and advanced equipment configurations to conduct dives that are deeper and/or longer than typical recreational air dives. The use of oxygen-nitrogen (nitrox) mixes with oxygen fractions higher than air results in longer no-decompression limits for shallow diving, and faster decompression from deeper dives. For depths beyond the air-diving range, technical divers mix helium, a light non-narcotic gas, with nitrogen and oxygen to produce 'trimix'. These blends are tailored to the depth of intended use with a fraction of oxygen calculated to produce an inspired oxygen partial pressure unlikely to cause cerebral oxygen toxicity and a nitrogen fraction calculated to produce a tolerable degree of nitrogen narcosis. A typical deep technical dive will involve the use of trimix at the target depth with changes to gases containing more oxygen and less inert gas during the decompression. Open-circuit scuba may be used to carry and utilise such gases, but this is very wasteful of expensive helium. There is increasing use of closed-circuit 'rebreather' devices. These recycle expired gas and potentially limit gas consumption to a small amount of inert gas to maintain the volume of the breathing circuit during descent and the amount of oxygen metabolised by the diver. This paper reviews the basic approach to planning and execution of dives using these methods to better inform physicians of the physical demands and risks.

  2. Using Word Identification Fluency to Monitor First-Grade Reading Development

    ERIC Educational Resources Information Center

    Zumeta, Rebecca O.; Compton, Donald L.; Fuchs, Lynn S.

    2012-01-01

    This study assessed the effects of sampling breadth on technical features of word identification fluency (WIF), a tool for screening and monitoring the reading development of first graders. From a potential pool of 704 first-grade students, the authors measured both a representative sample (n = 284) and 2 other subgroups: those with low reading…

  3. Recidivism Study: Positive Terminations from J. F. Ingram State Technical College, 1976-1986.

    ERIC Educational Resources Information Center

    Cogburn, Helen E.

    In 1988, a study was conducted by the J. F. Ingram State Technical College (ISTC) to determine recidivism rates for incarcerated individuals who earned a diploma and/or a General Educational Development (GED) certificate at ISTC during the years 1976 through 1986. The identification numbers of 2,844 students who had completed programs at ISTC were…

  4. Advances in biological dosimetry

    NASA Astrophysics Data System (ADS)

    Ivashkevich, A.; Ohnesorg, T.; Sparbier, C. E.; Elsaleh, H.

    2017-01-01

    Rapid retrospective biodosimetry methods are essential for the fast triage of persons occupationally or accidentally exposed to ionizing radiation. Identification and detection of a radiation specific molecular ‘footprint’ should provide a sensitive and reliable measurement of radiation exposure. Here we discuss conventional (cytogenetic) methods of detection and assessment of radiation exposure in comparison to emerging approaches such as gene expression signatures and DNA damage markers. Furthermore, we provide an overview of technical and logistic details such as type of sample required, time for sample preparation and analysis, ease of use and potential for a high throughput analysis.

  5. Air pollution source identification

    NASA Technical Reports Server (NTRS)

    Fordyce, J. S.

    1975-01-01

    The techniques available for source identification are reviewed: remote sensing, injected tracers, and pollutants themselves as tracers. The use of the large number of trace elements in the ambient airborne particulate matter as a practical means of identifying sources is discussed. Trace constituents are determined by sensitive, inexpensive, nondestructive, multielement analytical methods such as instrumental neutron activation and charged particle X-ray fluorescence. The application to a large data set of pairwise correlation, the more advanced pattern recognition-cluster analysis approach with and without training sets, enrichment factors, and pollutant concentration rose displays for each element is described. It is shown that elemental constituents are related to specific source types: earth crustal, automotive, metallurgical, and more specific industries. A field-ready source identification system based on time and wind direction resolved sampling is described.

  6. ADVANCEMENTS IN NEUTRON RADIOGRAPHY WITHIN THE DEPARTMENT OF THE ARMY

    DTIC Science & Technology

    2016-11-01

    Defense (DoD) production facility for direct use in quality control of munitions and weapons system by means of neutron radiographic inspection...UNCLASSIFIED UNCLASSIFIED AD-E403 813 Technical Report AREIS-TR-16004 ADVANCEMENTS IN NEUTRON RADIOGRAPHY WITHIN THE...REPORT DATE (DD-MM-YYYY) November 2016 2. REPORT TYPE Final 3. DATES COVERED (From – To) 4. TITLE AND SUBTITLE ADVANCEMENTS IN NEUTRON

  7. TECHcitement: Advances in Technological Education, 2004

    ERIC Educational Resources Information Center

    American Association of Community Colleges (NJ1), 2004

    2004-01-01

    This edition of "TECHcitement" contains the following articles: (1) ATE Program Leads to Student Success; (2) Doing Whatever It Takes for Aquaculture; (3) The Bridge to Biotech; (4) Girls See What They Can Do With Technology at Camp; (5) Students Advancing Solutions to Business Problems; (6) CREATE Recreates Technical Education in California; (7)…

  8. The Influence of Race, Ethnicity, and Gender on Advancement in Information Technology

    ERIC Educational Resources Information Center

    McGee, Kimberly

    2017-01-01

    This study investigated the experiences of African American/Black, Asian American, Caucasian American/White, and Latina/Hispanic American women who advanced from operational or technical IT roles to senior executive IT roles. The intent was to understand how individual and organizational factors influenced the women's career advancement journey…

  9. What Is New in Clinical Microbiology—Microbial Identification by MALDI-TOF Mass Spectrometry

    PubMed Central

    Murray, Patrick R.

    2012-01-01

    Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) offers the possibility of accurate, rapid, inexpensive identification of bacteria, fungi, and mycobacteria isolated in clinical microbiology laboratories. The procedures for preanalytic processing of organisms and analysis by MALDI-TOF MS are technically simple and reproducible, and commercial databases and interpretive algorithms are available for the identification of a wide spectrum of clinically significant organisms. Although only limited work has been reported on the use of this technique to identify molds, perform strain typing, or determine antibiotic susceptibility results, these are fruitful areas of promising research. As experience is gained with MALDI-TOF MS, it is expected that the databases will be expanded to resolve many of the current inadequate identifications (eg, no identification, genus-level identification) and algorithms for potential misidentification will be developed. The current lack of Food and Drug Administration approval of any MALDI-TOF MS system for organism identification limits widespread use in the United States. PMID:22795961

  10. Advances in Educational and Psychological Testing: Theory and Applications. Evaluation in Education and Human Services Series.

    ERIC Educational Resources Information Center

    Hambleton, Ronald K., Ed.; Zaal, Jac N., Ed.

    The 14 chapters of this book focus on the technical advances, advances in applied settings, and emerging topics in the testing field. Part 1 discusses methodological advances, Part 2 considers developments in applied settings, and Part 3 reviews emerging topics in the field of testing. Part 1 papers include: (1) "Advances in…

  11. Talent identification and selection process of outfield players and goalkeepers in a professional soccer club.

    PubMed

    Gil, Susana María; Zabala-Lili, Jon; Bidaurrazaga-Letona, Iraia; Aduna, Badiola; Lekue, Jose Antonio; Santos-Concejero, Jordan; Granados, Cristina

    2014-12-01

    Abstract The aim of this study was to analyse the talent identification process of a professional soccer club. A preselection of players (n = 64) aged 9-10 years and a final selection (n = 21) were performed by the technical staff through the observation during training sessions and matches. Also, 34 age-matched players of an open soccer camp (CampP) acted as controls. All participants underwent anthropometric, maturity and performance measurements. Preselected outfield players (OFs) were older and leaner than CampP (P < 0.05). Besides, they performed better in velocity, agility, endurance and jump tests (P < 0.05). A discriminant analysis showed that velocity and agility were the most important parameters. Finally, selected OFs were older and displayed better agility and endurance compared to the nonselected OFs (P < 0.05). Goalkeepers (GKs) were taller and heavier and had more body fat than OFs; also, they performed worse in the physical tests (P < 0.05). Finally, selected GKs were older and taller, had a higher predicted height and advanced maturity and performed better in the handgrip (dynamometry) and jump tests (P < 0.05). Thus, the technical staff selected OFs with a particular anthropometry and best performance, particularly agility and endurance, while GKs had a different profile. Moreover, chronological age had an important role in the whole selection process.

  12. NASA Space Environments Technical Discipline Team Space Weather Activities

    NASA Astrophysics Data System (ADS)

    Minow, J. I.; Nicholas, A. C.; Parker, L. N.; Xapsos, M.; Walker, P. W.; Stauffer, C.

    2017-12-01

    The Space Environment Technical Discipline Team (TDT) is a technical organization led by NASA's Technical Fellow for Space Environments that supports NASA's Office of the Chief Engineer through the NASA Engineering and Safety Center. The Space Environments TDT conducts independent technical assessments related to the space environment and space weather impacts on spacecraft for NASA programs and provides technical expertise to NASA management and programs where required. This presentation will highlight the status of applied space weather activities within the Space Environment TDT that support development of operational space weather applications and a better understanding of the impacts of space weather on space systems. We will first discuss a tool that has been developed for evaluating space weather launch constraints that are used to protect launch vehicles from hazardous space weather. We then describe an effort to better characterize three-dimensional radiation transport for CubeSat spacecraft and processing of micro-dosimeter data from the International Space Station which the team plans to make available to the space science community. Finally, we will conclude with a quick description of an effort to maintain access to the real-time solar wind data provided by the Advanced Composition Explorer satellite at the Sun-Earth L1 point.

  13. Irreversible electroporation of stage 3 locally advanced pancreatic cancer: optimal technique and outcomes

    PubMed Central

    2015-01-01

    Objective Irreversible electroporation (IRE) of stage 3 pancreatic adenocarcinoma has been used to provide quality of life time in patients who have undergone appropriate induction therapy. The optimal technique has been reported within the literature, but not in video form. IRE of locally advanced pancreatic cancer is technically demanding requiring precision ultrasound use for continuous imaging in multiple needle placements and during IRE energy delivery. Methods Appropriate patients with locally advanced pancreatic cancer should have undergone appropriate induction chemotherapy for a reasonable duration. The safe and effective technique for irreversible electroporation is preformed through an open approach with the emphasis on intra-operative ultrasound and intra-operative electroporation management. Results The technique of open irreversible electroporation of the pancreas involves bracketing the target tumor with IRE probes and any and all invaded vital structures including the celiac axis, superior mesenteric artery (SMA), superior mesenteric-portal vein, and bile duct with continuous intraoperative ultrasound imaging through a caudal to cranial approach. Optimal IRE delivery requires a change in amperage of at least 12 amps from baseline tissue conductivity in order to achieve technical success. Multiple pull-backs are necessary since the IRE ablation probe lengths are 1 cm and thus needed to achieve technical success along the caudal to cranial plane. Conclusions Irreversible electroporation in combination with multi-modality therapy for locally advanced pancreatic carcinoma is feasible for appropriate patients with locally advanced cancer. Technical demands are high and require the highest quality ultrasound for precise spacing measurements and optimal delivery to ensure adequate change in tissue resistance. PMID:29075594

  14. Whale Identification

    NASA Technical Reports Server (NTRS)

    1991-01-01

    R:BASE for DOS, a computer program developed under NASA contract, has been adapted by the National Marine Mammal Laboratory and the College of the Atlantic to provide and advanced computerized photo matching technique for identification of humpback whales. The program compares photos with stored digitized descriptions, enabling researchers to track and determine distribution and migration patterns. R:BASE is a spinoff of RIM (Relational Information Manager), which was used to store data for analyzing heat shielding tiles on the Space Shuttle Orbiter. It is now the world's second largest selling line of microcomputer database management software.

  15. Final Technical Report on the Institute for Advanced Study in Student Personnel Work.

    ERIC Educational Resources Information Center

    Callis, Robert

    This document reports the planning, implementation, and evaluation of a 9-month institute held at the University of Missouri-Columbia to prepare participants (approximately 20) for leadership positions in student personnel work at junior colleges and technical institutes. The following aspects of the instructional program are discussed and…

  16. A RICH detector for hadron identification at Jlab

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mammoliti, Francesco; Cisbani, Evaristo; Cusanno, Francesco

    2011-08-01

    The “standard” Hall A apparatus at Jefferson Lab (TOF and aerogel threshold Cherenkov detectors) does not provide complete identification for proton, kaon and pion. To this aim, a proximity focusing C6F14/CsI RICH (Ring Image Cherenkov) detector has been designed, built, tested and operated to separate kaons from pions with a pion contamination of a few percent up to 2.4 GeV/c. Two quite different experimental investigations have benefitted of the RICH identification: on one side, the high-resolution hypernuclear spectroscopy series of experiments on carbon, beryllium and oxygen, devoted to the study of the lambda-nucleon potential. On the other side, the measurementsmore » of the single spin asymmetries of pion and kaon on a transversely polarized 3He target are of utmost interest in understanding QCD dynamics in the nucleon. We present the technical features of such a RICH detector and comment on the presently achieved performance in hadron identification.« less

  17. A new data architecture for advancing life cycle assessment

    EPA Science Inventory

    IntroductionLife cycle assessment (LCA) has a technical architecture that limits data interoperability, transparency, and automated integration of external data. More advanced information technologies offer promise for increasing the ease with which information can be synthesized...

  18. McKenzie River Subbasin Assessment, Technical Report 2000.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Alsea Geospatial, Inc.

    2000-02-01

    This document details the findings of the McKenzie River Subbasin Assessment team. The goal of the subbasin assessment is to provide an ecological assessment of the McKenzie River Floodplain, identification of conservation and restoration opportunities, and discussion of the influence of some upstream actions and processes. This Technical Report can be viewed in conjunction with the McKenzie River Subbasin Summary or as a stand-alone document. The purpose of the technical report is to detail the methodology and findings of the consulting team that the observations and recommendations in the summary document are based on. This part, Part I, provides anmore » introduction to the subbasin and a general overview. Part II details the specific findings of the science team. Part III provides an explanation and examples of how to use the data that has been developed through this assessment to aid in prioritizing restoration activities. Part III also includes the literature cited and appendices.« less

  19. Highlights of the advances in basic immunology in 2011.

    PubMed

    Liu, Juan; Liu, Shuxun; Cao, Xuetao

    2012-05-01

    In this review, we summarize the major fundamental advances in immunological research reported in 2011. The highlights focus on the improved understanding of key questions in basic immunology, including the initiation and activation of innate responses as well as mechanisms for the development and function of various T-cell subsets. The research includes the identification of novel cytosolic RNA and DNA sensors as well as the identification of the novel regulators of the Toll-like receptor (TLR) and retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) signaling pathway. Moreover, remarkable advances have been made in the developmental and functional properties of innate lymphoid cells (ILCs). Helper T cells and regulatory T (Treg) cells play indispensable roles in orchestrating adaptive immunity. There have been exciting discoveries regarding the regulatory mechanisms of the development of distinct T-cell subsets, particularly Th17 cells and Treg cells. The emerging roles of microRNAs (miRNAs) in T cell immunity are discussed, as is the recent identification of a novel T-cell subset referred to as follicular regulatory T (TFR) cells.

  20. Highlights of the advances in basic immunology in 2011

    PubMed Central

    Liu, Juan; Liu, Shuxun; Cao, Xuetao

    2012-01-01

    In this review, we summarize the major fundamental advances in immunological research reported in 2011. The highlights focus on the improved understanding of key questions in basic immunology, including the initiation and activation of innate responses as well as mechanisms for the development and function of various T-cell subsets. The research includes the identification of novel cytosolic RNA and DNA sensors as well as the identification of the novel regulators of the Toll-like receptor (TLR) and retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) signaling pathway. Moreover, remarkable advances have been made in the developmental and functional properties of innate lymphoid cells (ILCs). Helper T cells and regulatory T (Treg) cells play indispensable roles in orchestrating adaptive immunity. There have been exciting discoveries regarding the regulatory mechanisms of the development of distinct T-cell subsets, particularly Th17 cells and Treg cells. The emerging roles of microRNAs (miRNAs) in T cell immunity are discussed, as is the recent identification of a novel T-cell subset referred to as follicular regulatory T (TFR) cells. PMID:22522654

  1. New Training Technologies. Studies on Technical and Vocational Education 2.

    ERIC Educational Resources Information Center

    Herremans, Albert

    This book is the second in a series aiming to promote international exchange of ideas, experiences, and studies relating to technical and vocational education. Information provided is designed to help educators and trainers plan for an intelligent use of new training technologies (NTTs) to improve the access to basic and advanced lifelong learning…

  2. The impact of emerging technologies on an advanced supersonic transport

    NASA Technical Reports Server (NTRS)

    Driver, C.; Maglieri, D. J.

    1986-01-01

    The effects of advances in propulsion systems, structure and materials, aerodynamics, and systems on the design and development of supersonic transport aircraft are analyzed. Efficient propulsion systems with variable-cycle engines provide the basis for improved propulsion systems; the propulsion efficienies of supersonic and subsonic engines are compared. Material advances consist of long-life damage-tolerant structures, advanced material development, aeroelastic tailoring, and low-cost fabrication. Improvements in the areas of aerodynamics and systems are examined. The environmental problems caused by engine emissions, airport noise, and sonic boom are studied. The characteristics of the aircraft designed to include these technical advances are described.

  3. Technical Factors Influencing Cone Packing Density Estimates in Adaptive Optics Flood Illuminated Retinal Images

    PubMed Central

    Lombardo, Marco; Serrao, Sebastiano; Lombardo, Giuseppe

    2014-01-01

    Purpose To investigate the influence of various technical factors on the variation of cone packing density estimates in adaptive optics flood illuminated retinal images. Methods Adaptive optics images of the photoreceptor mosaic were obtained in fifteen healthy subjects. The cone density and Voronoi diagrams were assessed in sampling windows of 320×320 µm, 160×160 µm and 64×64 µm at 1.5 degree temporal and superior eccentricity from the preferred locus of fixation (PRL). The technical factors that have been analyzed included the sampling window size, the corrected retinal magnification factor (RMFcorr), the conversion from radial to linear distance from the PRL, the displacement between the PRL and foveal center and the manual checking of cone identification algorithm. Bland-Altman analysis was used to assess the agreement between cone density estimated within the different sampling window conditions. Results The cone density declined with decreasing sampling area and data between areas of different size showed low agreement. A high agreement was found between sampling areas of the same size when comparing density calculated with or without using individual RMFcorr. The agreement between cone density measured at radial and linear distances from the PRL and between data referred to the PRL or the foveal center was moderate. The percentage of Voronoi tiles with hexagonal packing arrangement was comparable between sampling areas of different size. The boundary effect, presence of any retinal vessels, and the manual selection of cones missed by the automated identification algorithm were identified as the factors influencing variation of cone packing arrangements in Voronoi diagrams. Conclusions The sampling window size is the main technical factor that influences variation of cone density. Clear identification of each cone in the image and the use of a large buffer zone are necessary to minimize factors influencing variation of Voronoi diagrams of the cone

  4. Technical factors influencing cone packing density estimates in adaptive optics flood illuminated retinal images.

    PubMed

    Lombardo, Marco; Serrao, Sebastiano; Lombardo, Giuseppe

    2014-01-01

    To investigate the influence of various technical factors on the variation of cone packing density estimates in adaptive optics flood illuminated retinal images. Adaptive optics images of the photoreceptor mosaic were obtained in fifteen healthy subjects. The cone density and Voronoi diagrams were assessed in sampling windows of 320×320 µm, 160×160 µm and 64×64 µm at 1.5 degree temporal and superior eccentricity from the preferred locus of fixation (PRL). The technical factors that have been analyzed included the sampling window size, the corrected retinal magnification factor (RMFcorr), the conversion from radial to linear distance from the PRL, the displacement between the PRL and foveal center and the manual checking of cone identification algorithm. Bland-Altman analysis was used to assess the agreement between cone density estimated within the different sampling window conditions. The cone density declined with decreasing sampling area and data between areas of different size showed low agreement. A high agreement was found between sampling areas of the same size when comparing density calculated with or without using individual RMFcorr. The agreement between cone density measured at radial and linear distances from the PRL and between data referred to the PRL or the foveal center was moderate. The percentage of Voronoi tiles with hexagonal packing arrangement was comparable between sampling areas of different size. The boundary effect, presence of any retinal vessels, and the manual selection of cones missed by the automated identification algorithm were identified as the factors influencing variation of cone packing arrangements in Voronoi diagrams. The sampling window size is the main technical factor that influences variation of cone density. Clear identification of each cone in the image and the use of a large buffer zone are necessary to minimize factors influencing variation of Voronoi diagrams of the cone mosaic.

  5. Advances towards reliable identification and concentration determination of rare cells in peripheral blood

    NASA Astrophysics Data System (ADS)

    Alemany Server, R.; Martens, D.; Jans, K.; Bienstman, P.; Hill, D.

    2016-03-01

    Through further development, integration and validation of micro-nano-bio and biophotonics systems FP7 CanDo is developing an instrument that will permit highly reproducible and reliable identification and concentration determination of rare cells in peripheral blood for two key societal challenges, early and low cost anti-cancer drug efficacy determination and cancer diagnosis/monitoring. A cellular link between the primary malignant tumour and the peripheral metastases, responsible for 90% of cancerrelated deaths, has been established in the form of circulating tumour cells (CTCs) in peripheral blood. Furthermore, the relatively short survival time of CTCs in peripheral blood means that their detection is indicative of tumour progression thereby providing in addition to a prognostic value an evaluation of therapeutic efficacy and early recognition of tumour progression in theranostics. In cancer patients however blood concentrations are very low (=1 CTC/1E9 cells) and current detection strategies are too insensitive, limiting use to prognosis of only those with advanced metastatic cancer. Similarly, problems occur in therapeutics with anti-cancer drug development leading to lengthy and costly trials often preventing access to market. The novel cell separation/Raman analysis technologies plus nucleic acid based molecular characterization of the CanDo platform will provide an accurate CTC count with high throughput and high yield meeting both key societal challenges. Being beyond the state of art it will lead to substantial share gains not just in the high end markets of drug discovery and cancer diagnostics but due to modular technologies also in others. Here we present preliminary DNA hybridization sensing results.

  6. Technical considerations in continuous jugular venous oxygen saturation measurement.

    PubMed

    Dearden, N M; Midgley, S

    1993-01-01

    Fibreoptic reflection oximetry allows continuous in-vivo estimation of jugular venous oxygen saturation. In combination with pulse oximetry the oxygen extraction ratio SaO2-SjO2/SaO2 can be derived enabling identification of states of global luxury perfusion, normal coupling of global cerebral blood flow with global cerebral metabolism, global cerebral hypoperfusion and global cerebral ischemia. Several technical difficulties may arise affecting the accuracy of SjO2 recordings which must be recognised by the clinician before medical intervention is contemplated.

  7. Systematic development of technical textiles

    NASA Astrophysics Data System (ADS)

    Beer, M.; Schrank, V.; Gloy, Y.-S.; Gries, T.

    2016-07-01

    Technical textiles are used in various fields of applications, ranging from small scale (e.g. medical applications) to large scale products (e.g. aerospace applications). The development of new products is often complex and time consuming, due to multiple interacting parameters. These interacting parameters are production process related and also a result of the textile structure and used material. A huge number of iteration steps are necessary to adjust the process parameter to finalize the new fabric structure. A design method is developed to support the systematic development of technical textiles and to reduce iteration steps. The design method is subdivided into six steps, starting from the identification of the requirements. The fabric characteristics vary depending on the field of application. If possible, benchmarks are tested. A suitable fabric production technology needs to be selected. The aim of the method is to support a development team within the technology selection without restricting the textile developer. After a suitable technology is selected, the transformation and correlation between input and output parameters follows. This generates the information for the production of the structure. Afterwards, the first prototype can be produced and tested. The resulting characteristics are compared with the initial product requirements.

  8. Food and forensic molecular identification: update and challenges.

    PubMed

    Teletchea, Fabrice; Maudet, Celia; Hänni, Catherine

    2005-07-01

    The need for accurate and reliable methods for animal species identification has steadily increased during past decades, particularly with the recent food scares and the overall crisis of biodiversity primarily resulting from the huge ongoing illegal traffic of endangered species. A relatively new biotechnological field, known as species molecular identification, based on the amplification and analysis of DNA, offers promising solutions. Indeed, despite the fact that retrieval and analysis of DNA in processed products is a real challenge, numerous technically consistent methods are now available and allow the detection of animal species in almost any organic substrate. However, this field is currently facing a turning point and should rely more on knowledge primarily from three fundamental fields--paleogenetics, molecular evolution and systematics.

  9. EarthCube Activities: Community Engagement Advancing Geoscience Research

    NASA Astrophysics Data System (ADS)

    Kinkade, D.

    2015-12-01

    Our ability to advance scientific research in order to better understand complex Earth systems, address emerging geoscience problems, and meet societal challenges is increasingly dependent upon the concept of Open Science and Data. Although these terms are relatively new to the world of research, Open Science and Data in this context may be described as transparency in the scientific process. This includes the discoverability, public accessibility and reusability of scientific data, as well as accessibility and transparency of scientific communication (www.openscience.org). Scientists and the US government alike are realizing the critical need for easy discovery and access to multidisciplinary data to advance research in the geosciences. The NSF-supported EarthCube project was created to meet this need. EarthCube is developing a community-driven common cyberinfrastructure for the purpose of accessing, integrating, analyzing, sharing and visualizing all forms of data and related resources through advanced technological and computational capabilities. Engaging the geoscience community in EarthCube's development is crucial to its success, and EarthCube is providing several opportunities for geoscience involvement. This presentation will provide an overview of the activities EarthCube is employing to entrain the community in the development process, from governance development and strategic planning, to technical needs gathering. Particular focus will be given to the collection of science-driven use cases as a means of capturing scientific and technical requirements. Such activities inform the development of key technical and computational components that collectively will form a cyberinfrastructure to meet the research needs of the geoscience community.

  10. Building Communities of Engineers to Share Technical Expertise

    NASA Technical Reports Server (NTRS)

    Topousis, Daria E.; Dennehy, Cornelius J.; Fesq, Lorraine M.

    2012-01-01

    Developed by the core community to describe our vision of an approach to ensure a sufficiently technically advanced and affordable AR&D technology base is available to support future NASA missions. The goal of this strategy is to create an environment exploiting reusable technology elements for an AR&D system design and development process which is: a) Lower-Risk. b) More Versatile/Scalable. c) Reliable & Crew-Safe. d) More Affordable.

  11. Work, Leisure Time and Adult Education in Technically Advanced Industrial Countries.

    ERIC Educational Resources Information Center

    European Centre for Leisure and Education, Prague (Czechoslovakia).

    An outline of the increasing amount of change required of modern man, specifically in Czechoslovakia, to cope with the demands of a rapidly advancing technology is presented. Consideration is given to leisure time, work requirements, and educational needs. (CK)

  12. Advanced Thermal Emission Imaging Systems Definition and Development

    NASA Technical Reports Server (NTRS)

    Blasius, Karl; Nava, David (Technical Monitor)

    2002-01-01

    Santa Barbara Remote Sensing (SBRS), Raytheon Company, is pleased to submit this quarterly progress report of the work performed in the third quarter of Year 2 of the Advanced THEMIS Project, July through September 2002. We review here progress in the proposed tasks. During July through September 2002 progress was made in two major tasks, Spectral Response Characterization and Flight Instrument Definition. Because of staffing problems and technical problems earlier in the program we have refocused the remaining time and budget on the key technical tasks. Current technical problems with a central piece of test equipment has lead us to request a 1 quarter extension to the period of performance. This request is being made through a separate letter independent of this report.

  13. MDRC's Career and Technical Education Projects. Issue Focus

    ERIC Educational Resources Information Center

    MDRC, 2017

    2017-01-01

    The past decade has seen a resurgence of interest in career and technical education (CTE) as a way to engage students, help people build the skills necessary to succeed in a technologically advanced economy, and meet employer demand for workers. MDRC--which has a two-decade history of developing and evaluating CTE programs, including their…

  14. 77 FR 12823 - Advanced Scientific Computing Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... Exascale ARRA projects--Magellan final report, Advanced Networking update Status from Computer Science COV Early Career technical talks Summary of Applied Math and Computer Science Workshops ASCR's new SBIR..., Office of Science. ACTION: Notice of Open Meeting. SUMMARY: This notice announces a meeting of the...

  15. Nonculture molecular techniques for diagnosis of bacterial disease in animals: a diagnostic laboratory perspective.

    PubMed

    Cai, H Y; Caswell, J L; Prescott, J F

    2014-03-01

    The past decade has seen remarkable technical advances in infectious disease diagnosis, and the pace of innovation is likely to continue. Many of these techniques are well suited to pathogen identification directly from pathologic or clinical samples, which is the focus of this review. Polymerase chain reaction (PCR) and gene sequencing are now routinely performed on frozen or fixed tissues for diagnosis of bacterial infections of animals. These assays are most useful for pathogens that are difficult to culture or identify phenotypically, when propagation poses a biosafety hazard, or when suitable fresh tissue is not available. Multiplex PCR assays, DNA microarrays, in situ hybridization, massive parallel DNA sequencing, microbiome profiling, molecular typing of pathogens, identification of antimicrobial resistance genes, and mass spectrometry are additional emerging technologies for the diagnosis of bacterial infections from pathologic and clinical samples in animals. These technical advances come, however, with 2 caveats. First, in the age of molecular diagnosis, quality control has become more important than ever to identify and control for the presence of inhibitors, cross-contamination, inadequate templates from diagnostic specimens, and other causes of erroneous microbial identifications. Second, the attraction of these technologic advances can obscure the reality that medical diagnoses cannot be made on the basis of molecular testing alone but instead through integrated consideration of clinical, pathologic, and laboratory findings. Proper validation of the method is required. It is critical that veterinary diagnosticians understand not only the value but also the limitations of these technical advances for routine diagnosis of infectious disease.

  16. Meeting Students Where They Are: Advancing a Theory and Practice of Archives in the Classroom

    ERIC Educational Resources Information Center

    Saidy, Christina; Hannah, Mark; Sura, Tom

    2011-01-01

    This article uses theories of technical communication and archives to advance a pedagogy that includes archival production in the technical communication classroom. By developing and maintaining local classroom archives, students directly engage in valuable processes of appraisal, selection, collaboration, and retention. The anticipated outcomes…

  17. Automated Purgatoid Identification: Final Report

    NASA Technical Reports Server (NTRS)

    Wood, Steven

    2011-01-01

    Driving on Mars is hazardous: technical problems and unforeseen natural hazards can end a mission quickly at the worst, or result in long delays at best. This project is focused on helping to mitigate hazards posed to rovers by purgatoids: small (less than 1 m high, less than 10 m wide), ripple-like eolian bedforms commonly found scattered across the Meridiani Planum region of Mars. Due to the poorly consolidated nature of purgatoids and multiple past episodes of rovers getting stuck in them, identification and avoidance of these eolian bedforms is an important feature of rover path planning (NASA, 2011).

  18. Technical Competencies Applied in Experimental Fluid Dynamics

    NASA Astrophysics Data System (ADS)

    Tagg, Randall

    2017-11-01

    The practical design, construction, and operation of fluid dynamics experiments require a broad range of competencies. Three types are instrumental, procedural, and design. Respective examples would be operation of a spectrum analyzer, soft-soldering or brazing flow plumbing, and design of a small wind tunnel. Some competencies, such as the selection and installation of pumping systems, are unique to fluid dynamics and fluids engineering. Others, such as the design and construction of electronic amplifiers or optical imaging systems, overlap with other fields. Thus the identification and development of learning materials and methods for instruction are part of a larger effort to identify competencies needed in active research and technical innovation.

  19. Advanced transportation system studies. Technical area 2: Heavy lift launch vehicle development. Volume 2; Technical Results

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Sections 10 to 13 of the Advanced Transportation System Studies final report are included in this volume. Section 10 contains a copy of an executive summary that was prepared by Lockheed Space Operations Company (LSOC) to document their support to the TA-2 contract during the first-year period of performance of the contract, May 1992 through May 1993. LSOC participated on the TA-2 contract as part of the concurrent engineering launch system definition team, and provided outstanding heavy lift launch vehicle (HLLV) ground operations requirements and concept assessments for Lockheed Missiles and Space Company (LMSC) through an intercompany work transfer as well as providing specific HLLV ground operations assessments at the direction of NASA KSC through KSC funding that was routed to the TA-2 contract. Section 11 contains a copy of a vehicle-independent, launch system health management requirements assessment. The purpose of the assessment was to define both health management requirements and the associated interfaces between a generic advanced transportation system launch vehicle and all related elements of the entire transportation system, including the ground segment. Section 12 presents the major TA-2 presentations provided to summarize the significant results and conclusions that were developed over the course of the contract. Finally, Section 13 presents the design and assessment report on the first lunar outpost heavy lift launch vehicle.

  20. U.S. Air Force Scientific and Technical Information Program - The STINFO Program

    NASA Technical Reports Server (NTRS)

    Blados, Walter R.

    1991-01-01

    The U.S. Air Force STINFO (Scientific and Technical Information) program has as its main goal the proper use of all available scientific and technical information in the development of programs. The organization of STINFO databases, the use of STINFO in the development and advancement of aerospace science and technology and the acquisition of superior systems at lowest cost, and the application to public and private sectors of technologies developed for military uses are examined. STINFO user training is addressed. A project for aerospace knowledge diffusion is discussed.

  1. Port-of-entry advanced sorting system (PASS) operational test

    DOT National Transportation Integrated Search

    1998-12-01

    In 1992 the Oregon Department of Transportation undertook an operational test of the Port-of-Entry Advanced Sorting System (PASS), which uses a two-way communication automatic vehicle identification system, integrated with weigh-in-motion, automatic ...

  2. The evidence of the rugoscopy effectiveness as a human identification method in patients submitted to rapid palatal expansion.

    PubMed

    Barbieri, Ana A; Scoralick, Raquel A; Naressi, Suely C M; Moraes, Mari E L; Daruge, Eduardo; Daruge, Eduardo

    2013-01-01

    The objective of this study was to demonstrate the effectiveness of rugoscopy as a human identification method, even when the patient is submitted to rapid palatal expansion, which in theory would introduce doubt. With this intent, the Rugoscopic Identity was obtained for each subject using the classification formula proposed by Santos based on the intra-oral casts made before and after treatment from patients who were subjected to palatal expansion. The casts were labeled with the patients' initials and randomly arranged for studying. The palatine rugae kept the same patterns in every case studied. The technical error of the intra-evaluator measurement provided a confidence interval of 95%, making rugoscopy a reliable identification method for patients who were submitted to rapid palatal expansion, because even in the presence of intra-oral changes owing to the use of palatal expanders, the palatine rugae retained the biological and technical requirements for the human identification process. © 2012 American Academy of Forensic Sciences.

  3. Barriers to applying advanced high-temperature materials

    NASA Astrophysics Data System (ADS)

    Premkumar, M. K.

    1993-01-01

    During the past 25 years, aerospace engineers and material scientists have made significant technical progress toward developing next-generation aircraft. However, while advanced high-temperature materials continue to be developed, the outlook for their future application is uncertain and will depend on the ability of these materials to satisfy a more diverse market.

  4. Materials Testing and Quality Control Soils, 3-28. Military Curriculum Materials for Vocational and Technical Education.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. National Center for Research in Vocational Education.

    This instructional package on material testing and quality control of soils has been adapted from military curriculum materials for use in technical and vocational education programs. This short course presents basic information on soils as well as exploration, field identification, and laboratory procedures that will enable students completing…

  5. Identification, Characterization, and Evaluation Criteria for Systems Engineering Agile Enablers

    DTIC Science & Technology

    2015-01-16

    Identification, Characterization, and Evaluation Criteria for Systems Engineering Agile Enablers Technical Report SERC -2015-TR-049-1...Task Order 024, RT 124 Report No. SERC -2015-TR-049-1 Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the...Technology The Systems Engineering Research Center ( SERC ) is a federally funded University Affiliated Research Center managed by Stevens Institute of

  6. Respiratory Proteomics Today: Are Technological Advances for the Identification of Biomarker Signatures Catching up with Their Promise? A Critical Review of the Literature in the Decade 2004-2013.

    PubMed

    Viglio, Simona; Stolk, Jan; Iadarola, Paolo; Giuliano, Serena; Luisetti, Maurizio; Salvini, Roberta; Fumagalli, Marco; Bardoni, Anna

    2014-01-22

    To improve the knowledge on a variety of severe disorders, research has moved from the analysis of individual proteins to the investigation of all proteins expressed by a tissue/organism. This global proteomic approach could prove very useful: (i) for investigating the biochemical pathways involved in disease; (ii) for generating hypotheses; or (iii) as a tool for the identification of proteins differentially expressed in response to the disease state. Proteomics has not been used yet in the field of respiratory research as extensively as in other fields, only a few reproducible and clinically applicable molecular markers, which can assist in diagnosis, having been currently identified. The continuous advances in both instrumentation and methodology, which enable sensitive and quantitative proteomic analyses in much smaller amounts of biological material than before, will hopefully promote the identification of new candidate biomarkers in this area. The aim of this report is to critically review the application over the decade 2004-2013 of very sophisticated technologies to the study of respiratory disorders. The observed changes in protein expression profiles from tissues/fluids of patients affected by pulmonary disorders opens the route for the identification of novel pathological mediators of these disorders.

  7. Fundamental Materials Studies for Advanced High Power Microwave and Terahertz Vacuum Electronic Radiation Sources

    DTIC Science & Technology

    2014-12-10

    AFRL-OSR-VA-TR-2014-0359 Fundamental Materials Studies for Advanced High Power Microwave and Terahertz John Booske UNIVERSITY OF WISCONSIN SYSTEM...12-2014 Final Technical Performance Report October 1, 2011 - September 30, 2014 Fundamental Materials Studies for Advanced High Power Microwave and...emission-barrier scandate cathodes and identify related, alternative cathode materials systems for advanced vacuum electronic cathodes for high power THz

  8. Determination of metalaxyl and identification of adjuvants in wettable powder pesticide technical formulas.

    PubMed

    Pose-Juan, Eva; Rial-Otero, Raquel; Martínez-Carballo, Elena; López-Periago, Eugenio; Simal-Gándara, Jesús

    2009-07-01

    Foliar runoff is one of the most important processes affecting off-target movement of fungicides. In this way, Ridomil Gold Plus and Ridomil Gold MZ are two types of wettable powder technical formulations which contain metalaxyl and they are used for such a purpose. A method for quantitative determination of metalaxyl in pesticide formulas has been developed, validated, and subsequently applied to Ridomil Gold Plus and Ridomil Gold MZ. The method employs liquid-liquid extraction followed by liquid chromatography coupled with UV detection (LC-UV), using gas chromatography coupled with mass spectrometry as confirmation technique and to carry out a screening of organic adjuvants of these two selected pesticide formulas. Metalaxyl of 26.5 and 41 g/kg was detected in Ridomil Gold Plus and Ridomil Gold MZ, close to the manufacture specified level of 25 and 40 g/kg, respectively. Activator and utility adjuvants were detected in these two wettable powder technical formulations. Only methyl-ester-based surfactants were found within the group of nonionic surfactants, but the long-term fates of most adjuvants in soils and elsewhere in the environment are largely unknown, partially because of the lack of long-term monitoring data.

  9. Heterogeneous Teams of Autonomous Vehicles: Advanced Sensing & Control

    DTIC Science & Technology

    2009-03-01

    Final Technical 3. DATES COVERED (From To) 7/1/05-12/31708 4. TITLE AND SUBTITLE Heterogeneous Teams of Autonomous Vehicles Advanced Sensing...assimilating data from underwater and surface autonomous vehicles in addition to the usual sources of Eulerian and Lagrangian systems into a small scale

  10. 2017 Publications Demonstrate Advancements in Wind Energy Research

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    In 2017, wind energy experts at the National Renewable Energy Laboratory (NREL) made significant strides to advance wind energy. Many of these achievements were presented in articles published in scientific and engineering journals and technical reports that detailed research accomplishments in new and progressing wind energy technologies. During fiscal year 2017, NREL wind energy thought leaders shared knowledge and insights through 45 journal articles and 25 technical reports, benefiting academic and national-lab research communities; industry stakeholders; and local, state, and federal decision makers. Such publications serve as important outreach, informing the public of how NREL wind research, analysis, and deploymentmore » activities complement advanced energy growth in the United States and around the world. The publications also illustrate some of the noteworthy outcomes of U.S. Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) and Laboratory Directed Research and Development funding, as well as funding and facilities leveraged through strategic partnerships and other collaborations.« less

  11. Advancements in Distributed Learning (ADL) Environment in Support of Transformation

    DTIC Science & Technology

    2017-01-01

    REPORT TR-HFM-212 Advancements in Distributed Learning (ADL) Environment in Support of Transformation (Progrès en apprentissage distribué (ADL) à...l’appui de la transformation ) This report documents the findings of Task Group 212. The primary objective of this Task Group was to explore an agile...STO TECHNICAL REPORT TR-HFM-212 Advancements in Distributed Learning (ADL) Environment in Support of Transformation (Progrès en apprentissage

  12. The robotic Whipple: operative strategy and technical considerations.

    PubMed

    MacKenzie, Shawn; Kosari, Kambiz; Sielaff, Timothy; Johnson, Eric

    2011-03-01

    Advances in robotic surgery have allowed the frontiers of minimally invasive pancreatic surgery to expand. We present a step-by-step approach to the robotic Whipple procedure. The discussion includes port setting and robotic docking, kocherization and superior mesenteric vein identification, portal dissection, releasing the ligament of Treitz, uncinate dissection, and reconstruction. A brief report of our initial 2-year experience with the robotic Whipple procedure is also presented.

  13. Emerging New Strategies for Successful Metabolite Identification in Metabolomics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bingol, Ahmet K.; Bruschweiler-Li, Lei; Li, Dawei

    2016-02-26

    NMR is a very powerful tool for the identification of known and unknown (or unnamed) metabolites in complex mixtures as encountered in metabolomics. Known compounds can be reliably identified using 2D NMR methods, such as 13C-1H HSQC, for which powerful web servers with databases are available for semi-automated analysis. For the identification of unknown compounds, new combinations of NMR with MS have been developed recently that make synergistic use of the mutual strengths of the two techniques. The use of chemical additives to the NMR tube, such as reactive agents, paramagnetic ions, or charged silica nanoparticles, permit the identification ofmore » metabolites with specific physical chemical properties. In the following sections, we give an overview of some of the recent advances in metabolite identification and discuss remaining challenges.« less

  14. 29 CFR 1990.141 - Advance notice of proposed rulemaking.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 1990.141 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) IDENTIFICATION, CLASSIFICATION, AND REGULATION OF POTENTIAL OCCUPATIONAL CARCINOGENS Regulation of Potential Occupational Carcinogens § 1990.141 Advance notice of proposed rulemaking...

  15. 29 CFR 1990.141 - Advance notice of proposed rulemaking.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 1990.141 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) IDENTIFICATION, CLASSIFICATION, AND REGULATION OF POTENTIAL OCCUPATIONAL CARCINOGENS Regulation of Potential Occupational Carcinogens § 1990.141 Advance notice of proposed rulemaking...

  16. Advanced Structures: 2000-2004

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This custom bibliography from the NASA Scientific and Technical Information Program lists a sampling of records found in the NASA Aeronautics and Space Database. The scope of this topic includes technologies for extremely lightweight, multi-function structures with modular interfaces - the building-block technology for advanced spacecraft. This area of focus is one of the enabling technologies as defined by NASA s Report of the President s Commission on Implementation of United States Space Exploration Policy, published in June 2004.

  17. Identification of fungal phytopathogens using Fourier transform infrared-attenuated total reflection spectroscopy and advanced statistical methods

    NASA Astrophysics Data System (ADS)

    Salman, Ahmad; Lapidot, Itshak; Pomerantz, Ami; Tsror, Leah; Shufan, Elad; Moreh, Raymond; Mordechai, Shaul; Huleihel, Mahmoud

    2012-01-01

    The early diagnosis of phytopathogens is of a great importance; it could save large economical losses due to crops damaged by fungal diseases, and prevent unnecessary soil fumigation or the use of fungicides and bactericides and thus prevent considerable environmental pollution. In this study, 18 isolates of three different fungi genera were investigated; six isolates of Colletotrichum coccodes, six isolates of Verticillium dahliae and six isolates of Fusarium oxysporum. Our main goal was to differentiate these fungi samples on the level of isolates, based on their infrared absorption spectra obtained using the Fourier transform infrared-attenuated total reflection (FTIR-ATR) sampling technique. Advanced statistical and mathematical methods: principal component analysis (PCA), linear discriminant analysis (LDA), and k-means were applied to the spectra after manipulation. Our results showed significant spectral differences between the various fungi genera examined. The use of k-means enabled classification between the genera with a 94.5% accuracy, whereas the use of PCA [3 principal components (PCs)] and LDA has achieved a 99.7% success rate. However, on the level of isolates, the best differentiation results were obtained using PCA (9 PCs) and LDA for the lower wavenumber region (800-1775 cm-1), with identification success rates of 87%, 85.5%, and 94.5% for Colletotrichum, Fusarium, and Verticillium strains, respectively.

  18. Advanced building energy management system demonstration for Department of Defense buildings.

    PubMed

    O'Neill, Zheng; Bailey, Trevor; Dong, Bing; Shashanka, Madhusudana; Luo, Dong

    2013-08-01

    This paper presents an advanced building energy management system (aBEMS) that employs advanced methods of whole-building performance monitoring combined with statistical methods of learning and data analysis to enable identification of both gradual and discrete performance erosion and faults. This system assimilated data collected from multiple sources, including blueprints, reduced-order models (ROM) and measurements, and employed advanced statistical learning algorithms to identify patterns of anomalies. The results were presented graphically in a manner understandable to facilities managers. A demonstration of aBEMS was conducted in buildings at Naval Station Great Lakes. The facility building management systems were extended to incorporate the energy diagnostics and analysis algorithms, producing systematic identification of more efficient operation strategies. At Naval Station Great Lakes, greater than 20% savings were demonstrated for building energy consumption by improving facility manager decision support to diagnose energy faults and prioritize alternative, energy-efficient operation strategies. The paper concludes with recommendations for widespread aBEMS success. © 2013 New York Academy of Sciences.

  19. Advanced Technology for Engineering Education

    NASA Technical Reports Server (NTRS)

    Noor, Ahmed K. (Compiler); Malone, John B. (Compiler)

    1998-01-01

    This document contains the proceedings of the Workshop on Advanced Technology for Engineering Education, held at the Peninsula Graduate Engineering Center, Hampton, Virginia, February 24-25, 1998. The workshop was jointly sponsored by the University of Virginia's Center for Advanced Computational Technology and NASA. Workshop attendees came from NASA, other government agencies, industry and universities. The objectives of the workshop were to assess the status of advanced technologies for engineering education and to explore the possibility of forming a consortium of interested individuals/universities for curriculum reform and development using advanced technologies. The presentations covered novel delivery systems and several implementations of new technologies for engineering education. Certain materials and products are identified in this publication in order to specify adequately the materials and products that were investigated in the research effort. In no case does such identification imply recommendation or endorsement of products by NASA, nor does it imply that the materials and products are the only ones or the best ones available for this purpose. In many cases equivalent materials and products are available and would probably produce equivalent results.

  20. An Effective Health and Medical Technical Authority

    NASA Technical Reports Server (NTRS)

    Fogarty, Jennifer A.

    2009-01-01

    The NASA Governance model directed the formation of three Technical Authorities, Engineering; Safety and Mission Assurance; and Health and Medical, to ensure that risks are identified and adjudicated efficiently and transparently in concert with the spaceflight programs and projects. The Health and Medical Technical Authority (HMTA) has been implemented at the Johnson Space Center (JSC) and consists of the Chief Medical Office (CMO), the Deputy CMO, and HMTA Delegates. The JSC HMTA achieves the goals of risk identification and adjudication through the discharge of the appropriate technical expertise to human space flight programs and projects and the escalation of issues within program and technical authority boards. The JSC HMTA relies on subject matter experts (SMEs) in the Space Life Sciences Directorate at JSC as well as experts from other Centers to work crew health and performance issues at the technical level, develop requirements, oversee implementation and validation of requirements, and identify risks and non-compliances. Once a risk or potential noncompliance has been identified and reported to the programs or projects, the JSC HMTA begins to track it and closely monitor the program's or project's response. As a risk is developed or a non-compliance negotiated, positions from various levels of decision makers are sought at the program and project control boards. The HMTA may support a program or project position if it is satisfied with the decision making and vetting processes (ex. the subject matter expert voiced his/her concerns and all dissenting opinions were documented) and finds that the position both acknowledges the risk and cost of the mitigation and resolves the issue without changing NASA risk posture. The HMTA may disagree with a program or project position if the NASA risk posture has been elevated or obfuscated. If the HMTA does disagree with the program or project position, it will appeal to successively higher levels of authority so that

  1. The Shock and Vibration Digest. Volume 13, Number 5

    DTIC Science & Technology

    1981-05-01

    Ducts................ 82 Numerical Methods..107 VEHICLE SYSTEMS ........ 51 Building Components..85 Parameter Identification. . 107 Groud Veicls ...in Hybrid Systems Beam Vibrations W. Wed ig 68 Inst. for Technical Mechanics, Univ. of Karlsruhe, CYLINDERS Recent Advances in Structural Dynamics

  2. Advances in the Theory of Complex Networks

    NASA Astrophysics Data System (ADS)

    Peruani, Fernando

    An exhaustive and comprehensive review on the theory of complex networks would imply nowadays a titanic task, and it would result in a lengthy work containing plenty of technical details of arguable relevance. Instead, this chapter addresses very briefly the ABC of complex network theory, visiting only the hallmarks of the theoretical founding, to finally focus on two of the most interesting and promising current research problems: the study of dynamical processes on transportation networks and the identification of communities in complex networks.

  3. Legal basis of the Advanced Therapies Regulation.

    PubMed

    Jekerle, V; Schröder, C; Pedone, E

    2010-01-01

    Advanced therapy medicinal products consist of gene therapy, somatic cell therapy and tissue engineered products. Due to their specific manufacturing process and mode of action these products require specially tailored legislation. With Regulation (EC) No. 1394/2007, these needs have been met. Definitions of gene therapy, somatic cell therapy and tissue engineered products were laid down. A new committee, the Committee for Advanced Therapies, was founded, special procedures such as the certification procedure for small- and medium-sized enterprises were established and the technical requirements for Marketing Authorisation Applications (quality, non-clinical and clinical) were revised.

  4. INDOT Technical Training Plan : [Technical Summary

    DOT National Transportation Integrated Search

    2012-01-01

    A wide range of job classifications, increasing technical : performance expectations, licensing and certification requirements, : budget restrictions and frequent department : reorganization has made technical training of employees : more difficult, ...

  5. Advances in Sterilization and Decontamination: a Survey

    NASA Technical Reports Server (NTRS)

    1978-01-01

    Recent technical advances made in the field of sterilization and decontamination and their applicability to private and commercial interests are discussed. Government-sponsored programs by NASA produced the bulk of material presented in this survey. The summary of past and current research discussed is detailed to enhance an effective transfer of technology from NASA to potential users.

  6. Cultivating Advanced Technical Writing Skills through a Graduate-Level Course on Writing Research Proposals

    ERIC Educational Resources Information Center

    McCarthy, Brian D.; Dempsey, Jillian L.

    2017-01-01

    A graduate-level course focused on original research proposals is introduced to address the uneven preparation in technical writing of new chemistry graduate students. This course focuses on writing original research proposals. The general course structure features extensive group discussions, small-group activities, and regular in-class…

  7. Entropy based file type identification and partitioning

    DTIC Science & Technology

    2017-06-01

    energy spectrum,” Proceedings of the Twenty-Ninth International Florida Artificial Intelligence Research Society Conference, pp. 288–293, 2016...ABBREVIATIONS AES Advanced Encryption Standard ANN Artificial Neural Network ASCII American Standard Code for Information Interchange CWT...the identification of file types and file partitioning. This approach has applications in cybersecurity as it allows for a quick determination of

  8. Technical Processing Librarians in the 1980's: Current Trends and Future Forecasts.

    ERIC Educational Resources Information Center

    Kennedy, Gail

    1980-01-01

    This review of recent and anticipated advances in library automation technology and methodology includes a review of the effects of OCLC, MARC formatting, AACR2, and increasing costs, as well as predictions of the impact on library technical processing of networking, expansion of automation, minicomputers, specialized reference services, and…

  9. Advanced composite fuselage technology

    NASA Technical Reports Server (NTRS)

    Ilcewicz, Larry B.; Smith, Peter J.; Horton, Ray E.

    1993-01-01

    Boeing's ATCAS program has completed its third year and continues to progress towards a goal to demonstrate composite fuselage technology with cost and weight advantages over aluminum. Work on this program is performed by an integrated team that includes several groups within The Boeing Company, industrial and university subcontractors, and technical support from NASA. During the course of the program, the ATCAS team has continued to perform a critical review of composite developments by recognizing advances in metal fuselage technology. Despite recent material, structural design, and manufacturing advancements for metals, polymeric matrix composite designs studied in ATCAS still project significant cost and weight advantages for future applications. A critical path to demonstrating technology readiness for composite transport fuselage structures was created to summarize ATCAS tasks for Phases A, B, and C. This includes a global schedule and list of technical issues which will be addressed throughout the course of studies. Work performed in ATCAS since the last ACT conference is also summarized. Most activities relate to crown quadrant manufacturing scaleup and performance verification. The former was highlighted by fabricating a curved, 7 ft. by 10 ft. panel, with cocured hat-stiffeners and cobonded J-frames. In building to this scale, process developments were achieved for tow-placed skins, drape formed stiffeners, braided/RTM frames, and panel cure tooling. Over 700 tests and supporting analyses have been performed for crown material and design evaluation, including structural tests that demonstrated limit load requirements for severed stiffener/skin failsafe damage conditions. Analysis of tests for tow-placed hybrid laminates with large damage indicates a tensile fracture toughness that is higher than that observed for advanced aluminum alloys. Additional recent ATCAS achievements include crown supporting technology, keel quadrant design evaluation, and

  10. Evaluation of the Technical Adequacy of Three Methods for Identifying Specific Learning Disabilities Based on Cognitive Discrepancies

    ERIC Educational Resources Information Center

    Stuebing, Karla K.; Fletcher, Jack M.; Branum-Martin, Lee; Francis, David J.

    2012-01-01

    This study used simulation techniques to evaluate the technical adequacy of three methods for the identification of specific learning disabilities via patterns of strengths and weaknesses in cognitive processing. Latent and observed data were generated and the decision-making process of each method was applied to assess concordance in…

  11. High Efficiency Space Power Systems Project Advanced Space-Rated Batteries

    NASA Technical Reports Server (NTRS)

    Reid, Concha M.

    2011-01-01

    Case Western Reserve University (CWRU) has an agreement with China National Offshore Oil Corporation New Energy Investment Company, Ltd. (CNOOC), under the United States-China EcoPartnerships Framework, to create a bi-national entity seeking to develop technically feasible and economically viable solutions to energy and environmental issues. Advanced batteries have been identified as one of the initial areas targeted for collaborations. CWRU invited NASA Glenn Research Center (GRC) personnel from the Electrochemistry Branch to CWRU to discuss various aspects of advanced battery development as they might apply to this partnership. Topics discussed included: the process for the selection of a battery chemistry; the establishment of an integrated development program; project management/technical interactions; new technology developments; and synergies between batteries for automotive and space operations. Additional collaborations between CWRU and NASA GRC's Electrochemistry Branch were also discussed.

  12. INTERNATIONAL ENVIRONMENTAL TECHNOLOGY IDENTIFICATION, DEVELOPMENT, DEMONSTRATION, DEPLOYMENT AND EXCHANGE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roy C. Herndon

    2001-02-28

    Cooperative Agreement (DE-FC21-95EW55101) between the U.S. Department of Energy (DOE) and the Florida State University's Institute for International Cooperative Environmental Research (IICER) was designed to facilitate a number of joint programmatic goals of both the DOE and the IICER related to international technology identification, development, demonstration and deployment using a variety of mechanisms to accomplish these goals. These mechanisms included: laboratory and field research; technology demonstrations; international training and technical exchanges; data collection, synthesis and evaluation; the conduct of conferences, symposia and high-level meetings; and other appropriate and effective approaches. The DOE utilized the expertise and facilities of the IICERmore » at Florida State University to accomplish its goals related to this cooperative agreement. The IICER has unique and demonstrated capabilities that have been utilized to conduct the tasks for this cooperative agreement. The IICER conducted activities related to technology identification, development, evaluation, demonstration and deployment through its joint centers which link the capabilities at Florida State University with collaborating academic and leading research institutions in the major countries of Central and Eastern Europe (e.g., Czech Republic, Hungary, Poland) and Russia. The activities and accomplishments for this five-year cooperative agreement are summarized in this Final Technical Report.« less

  13. Technological advances in bovine mastitis diagnosis: an overview.

    PubMed

    Duarte, Carla M; Freitas, Paulo P; Bexiga, Ricardo

    2015-11-01

    Bovine mastitis is an economic burden for dairy farmers and preventive control measures are crucial for the sustainability of any dairy business. The identification of etiological agents is necessary in controlling the disease, reducing risk of chronic infections and targeting antimicrobial therapy. The suitability of a detection method for routine diagnosis depends on several factors, including specificity, sensitivity, cost, time in producing results, and suitability for large-scale sampling of milk. This article focuses on current methodologies for identification of mastitis pathogens and for detection of inflammation, as well as the advantages and disadvantages of different methods. Emerging technologies, such as transcriptome and proteome analyses and nano- and microfabrication of portable devices, offer promising, sensitive methods for advanced detection of mastitis pathogens and biomarkers of inflammation. The demand for alternative, fast, and reliable diagnostic procedures is rising as farms become bigger. Several examples of technological and scientific advances are summarized which have given rise to more sensitive, reliable and faster diagnostic results. © 2015 The Author(s).

  14. Strong Motion Network of Medellín and Aburrá Valley: technical advances, seismicity records and micro-earthquake monitoring

    NASA Astrophysics Data System (ADS)

    Posada, G.; Trujillo, J. C., Sr.; Hoyos, C.; Monsalve, G.

    2017-12-01

    The tectonics setting of Colombia is determined by the interaction of Nazca, Caribbean and South American plates, together with the Panama-Choco block collision, which makes a seismically active region. Regional seismic monitoring is carried out by the National Seismological Network of Colombia and the Accelerometer National Network of Colombia. Both networks calculate locations, magnitudes, depths and accelerations, and other seismic parameters. The Medellín - Aburra Valley is located in the Northern segment of the Central Cordillera of Colombia, and according to the Colombian technical seismic norm (NSR-10), is a region of intermediate hazard, because of the proximity to seismic sources of the Valley. Seismic monitoring in the Aburra Valley began in 1996 with an accelerometer network which consisted of 38 instruments. Currently, the network consists of 26 stations and is run by the Early Warning System of Medellin and Aburra Valley (SIATA). The technical advances have allowed the real-time communication since a year ago, currently with 10 stations; post-earthquake data is processed through operationally near-real-time, obtaining quick results in terms of location, acceleration, spectrum response and Fourier analysis; this information is displayed at the SIATA web site. The strong motion database is composed by 280 earthquakes; this information is the basis for the estimation of seismic hazards and risk for the region. A basic statistical analysis of the main information was carried out, including the total recorded events per station, natural frequency, maximum accelerations, depths and magnitudes, which allowed us to identify the main seismic sources, and some seismic site parameters. With the idea of a more complete seismic monitoring and in order to identify seismic sources beneath the Valley, we are in the process of installing 10 low-cost shake seismometers for micro-earthquake monitoring. There is no historical record of earthquakes with a magnitude

  15. Toward the development of portable miniature intelligent electronic color identification devices

    NASA Astrophysics Data System (ADS)

    Nicolau, Dan V., Jr.; Livingston, Peter; Jahshan, David; Evans, Rob

    2004-03-01

    The identification and differentiation of colours is a relatively problematic task for colour-impaired and partially vision-impaired persons and an impossible one for completely blind. In various contexts, this leads to a loss of independence or an increased risk of harm. The identification of colour using optoelectronic devices, on the other hand, can be done precisely and inexpensively. Additionally, breakthroughs in miniaturising and integrating colour sensors into biological systems may lead to significant advances in electronic implants for alleviating blindness. Here we present a functional handheld device developed for the identification of colour, intended for use by the vision-impaired. We discuss the features and limitations of the device and describe in detail one target application - the identification of different banknote denominations by the blind.

  16. Intellectual system of identification of Arabic graphics

    NASA Astrophysics Data System (ADS)

    Abdoullayeva, Gulchin G.; Aliyev, Telman A.; Gurbanova, Nazakat G.

    2001-08-01

    The studies made by using the domain of graphic images allowed creating facilities of the artificial intelligence for letters, letter combinations etc. for various graphics and prints. The work proposes a system of recognition and identification of symbols of the Arabic graphics, which has its own specificity as compared to Latin and Cyrillic ones. The starting stage of the recognition and the identification is coding with further entry of information into a computer. Here the problem of entry is one of the essentials. For entry of a large volume of information in the unit of time a scanner is usually employed. Along with the scanner the authors suggest their elaboration of technical facilities for effective input and coding of the information. For refinement of symbols not identified from the scanner mostly for a small bulk of information the developed coding devices are used directly in the process of writing. The functional design of the software is elaborated on the basis of the heuristic model of the creative activity of a researcher and experts in the description and estimation of states of the weakly formalizable systems on the strength of the methods of identification and of selection of geometric features.

  17. Space Launch System Advanced Development Office, FY 2013 Annual Report

    NASA Technical Reports Server (NTRS)

    Crumbly, C. M.; Bickley, F. P.; Hueter, U.

    2013-01-01

    The Advanced Development Office (ADO), part of the Space Launch System (SLS) program, provides SLS with the advanced development needed to evolve the vehicle from an initial Block 1 payload capability of 70 metric tons (t) to an eventual capability Block 2 of 130 t, with intermediary evolution options possible. ADO takes existing technologies and matures them to the point that insertion into the mainline program minimizes risk. The ADO portfolio of tasks covers a broad range of technical developmental activities. The ADO portfolio supports the development of advanced boosters, upper stages, and other advanced development activities benefiting the SLS program. A total of 34 separate tasks were funded by ADO in FY 2013.

  18. Simulated lumbar minimally invasive surgery educational model with didactic and technical components.

    PubMed

    Chitale, Rohan; Ghobrial, George M; Lobel, Darlene; Harrop, James

    2013-10-01

    The learning and development of technical skills are paramount for neurosurgical trainees. External influences and a need for maximizing efficiency and proficiency have encouraged advancements in simulator-based learning models. To confirm the importance of establishing an educational curriculum for teaching minimally invasive techniques of pedicle screw placement using a computer-enhanced physical model of percutaneous pedicle screw placement with simultaneous didactic and technical components. A 2-hour educational curriculum was created to educate neurosurgical residents on anatomy, pathophysiology, and technical aspects associated with image-guided pedicle screw placement. Predidactic and postdidactic practical and written scores were analyzed and compared. Scores were calculated for each participant on the basis of the optimal pedicle screw starting point and trajectory for both fluoroscopy and computed tomographic navigation. Eight trainees participated in this module. Average mean scores on the written didactic test improved from 78% to 100%. The technical component scores for fluoroscopic guidance improved from 58.8 to 52.9. Technical score for computed tomography-navigated guidance also improved from 28.3 to 26.6. Didactic and technical quantitative scores with a simulator-based educational curriculum improved objectively measured resident performance. A minimally invasive spine simulation model and curriculum may serve a valuable function in the education of neurosurgical residents and outcomes for patients.

  19. Spacecraft Impacts with Advanced Power and Electric Propulsion

    NASA Technical Reports Server (NTRS)

    Mason, Lee S.; Oleson, Steven R.

    2000-01-01

    A study was performed to assess the benefits of advanced power and electric propulsion systems for various space missions. Advanced power technologies that were considered included multiband gap and thin-film solar arrays, lithium batteries, and flywheels. Electric propulsion options included Hall effect thrusters and Ion thrusters. Several mission case studies were selected as representative of future applications for advanced power and propulsion systems. These included a low altitude Earth science satellite, a LEO communications constellation, a GEO military surveillance satellite, and a Mercury planetary mission. The study process entailed identification of overall mission performance using state-of-the-art power and propulsion technology, enhancements made possible with either power or electric propulsion advances individually, and the collective benefits realized when advanced power and electric propulsion are combined. Impacts to the overall spacecraft included increased payload, longer operational life, expanded operations and launch vehicle class step-downs.

  20. The role of technical advances in the adoption and integration of patient-reported outcomes in clinical care.

    PubMed

    Jensen, Roxanne E; Rothrock, Nan E; DeWitt, Esi M; Spiegel, Brennan; Tucker, Carole A; Crane, Heidi M; Forrest, Christopher B; Patrick, Donald L; Fredericksen, Rob; Shulman, Lisa M; Cella, David; Crane, Paul K

    2015-02-01

    Patient-reported outcomes (PROs) are gaining recognition as key measures for improving the quality of patient care in clinical care settings. Three factors have made the implementation of PROs in clinical care more feasible: increased use of modern measurement methods in PRO design and validation, rapid progression of technology (eg, touchscreen tablets, Internet accessibility, and electronic health records), and greater demand for measurement and monitoring of PROs by regulators, payers, accreditors, and professional organizations. As electronic PRO collection and reporting capabilities have improved, the challenges of collecting PRO data have changed. To update information on PRO adoption considerations in clinical care, highlighting electronic and technical advances with respect to measure selection, clinical workflow, data infrastructure, and outcomes reporting. Five practical case studies across diverse health care settings and patient populations are used to explore how implementation barriers were addressed to promote the successful integration of PRO collection into the clinical workflow. The case studies address selecting and reporting of relevant content, workflow integration, previsit screening, effective evaluation, and electronic health record integration. These case studies exemplify elements of well-designed electronic systems, including response automation, tailoring of item selection and reporting algorithms, flexibility of collection location, and integration with patient health care data elements. They also highlight emerging logistical barriers in this area, such as the need for specialized technological and methodological expertise, and design limitations of current electronic data capture systems.

  1. The Role of Technical Advances in the Adoption and Integration of Patient-Reported Outcomes in Clinical Care

    PubMed Central

    Jensen, Roxanne E.; Rothrock, Nan E.; DeWitt, Esi Morgan; Spiegel, Brennan; Tucker, Carole A.; Crane, Heidi M.; Forrest, Christopher B.; Patrick, Donald L.; Fredericksen, Rob; Shulman, Lisa M.; Cella, David; Crane, Paul K.

    2016-01-01

    Background Patient-reported outcomes (PROs) are gaining recognition as key measures for improving the quality of patient care in clinical care settings. Three factors have made the implementation of PROs in clinical care more feasible: increased use of modern measurement methods in PRO design and validation, rapid progression of technology (e.g., touch screen tablets, Internet accessibility, and electronic health records (EHRs)), and greater demand for measurement and monitoring of PROs by regulators, payers, accreditors, and professional organizations. As electronic PRO collection and reporting capabilities have improved, the challenges of collecting PRO data have changed. Objectives To update information on PRO adoption considerations in clinical care, highlighting electronic and technical advances with respect to measure selection, clinical workflow, data infrastructure, and outcomes reporting. Methods Five practical case studies across diverse healthcare settings and patient populations are used to explore how implementation barriers were addressed to promote the successful integration of PRO collection into the clinical workflow. The case studies address selecting and reporting of relevant content, workflow integration, pre-visit screening, effective evaluation, and EHR integration. Conclusions These case studies exemplify elements of well-designed electronic systems, including response automation, tailoring of item selection and reporting algorithms, flexibility of collection location, and integration with patient health care data elements. They also highlight emerging logistical barriers in this area, such as the need for specialized technological and methodological expertise, and design limitations of current electronic data capture systems. PMID:25588135

  2. A Dichotomous Key for the Identification of Common British Wild Flower Families

    ERIC Educational Resources Information Center

    Wood, Piers

    2004-01-01

    This article argues the need for, and provides, a dichotomous single access key for the identification of common British wild flower families. A minimum of technical vocabulary is used while at the same time retaining most of the recent botanical names of families. The key provides a user-friendly opportunity for school pupils to become familiar…

  3. The Technical Work Plan Tracking Tool

    NASA Technical Reports Server (NTRS)

    Chullen, Cinda; Leighton, Adele; Weller, Richard A.; Woodfill, Jared; Parkman, William E.; Ellis, Glenn L.; Wilson, Marilyn M.

    2003-01-01

    The Technical Work Plan Tracking Tool is a web-based application that enables interactive communication and approval of contract requirements that pertain to the administration of the Science, Engineering, Analysis, and Test (SEAT) contract at Johnson Space Center. The implementation of the application has (1) shortened the Technical Work Plan approval process, (2) facilitated writing and documenting requirements in a performance-based environment with associated surveillance plans, (3) simplified the contractor s estimate of the cost for the required work, and (4) allowed for the contractor to document how they plan to accomplish the work. The application is accessible to over 300 designated NASA and contractor employees via two Web sites. For each employee, the application regulates access according to the employee s authority to enter, view, and/or print out diverse information, including reports, work plans, purchase orders, and financial data. Advanced features of this application include on-line approval capability, automatic e-mail notifications requesting review by subsequent approvers, and security inside and outside the firewall.

  4. Application of dynamic traffic assignment to advanced managed lane modeling : [technical summary].

    DOT National Transportation Integrated Search

    2013-11-01

    Transportation agencies realize that, often, adding : lanes is not a feasible or effective solution for : increases in traffic congestion. So, agencies have : applied advanced strategies to better use existing : capacity. One such strategy, managed l...

  5. Advanced space communications architecture study. Volume 2: Technical report

    NASA Technical Reports Server (NTRS)

    Horstein, Michael; Hadinger, Peter J.

    1987-01-01

    The technical feasibility and economic viability of satellite system architectures that are suitable for customer premise service (CPS) communications are investigated. System evaluation is performed at 30/20 GHz (Ka-band); however, the system architectures examined are equally applicable to 14/11 GHz (Ku-band). Emphasis is placed on systems that permit low-cost user terminals. Frequency division multiple access (FDMA) is used on the uplink, with typically 10,000 simultaneous accesses per satellite, each of 64 kbps. Bulk demodulators onboard the satellite, in combination with a baseband multiplexer, convert the many narrowband uplink signals into a small number of wideband data streams for downlink transmission. Single-hop network interconnectivity is accomplished via downlink scanning beams. Each satellite is estimated to weigh 5600 lb and consume 6850W of power; the corresponding payload totals are 1000 lb and 5000 W. Nonrecurring satellite cost is estimated at $110 million, with the first-unit cost at $113 million. In large quantities, the user terminal cost estimate is $25,000. For an assumed traffic profile, the required system revenue has been computed as a function of the internal rate of return (IRR) on invested capital. The equivalent user charge per-minute of 64-kbps channel service has also been determined.

  6. Recent technologic advances in multi-detector row cardiac CT.

    PubMed

    Halliburton, Sandra Simon

    2009-11-01

    Recent technical advances in multi-detector row CT have resulted in lower radiation dose, improved temporal and spatial resolution, decreased scan time, and improved tissue differentiation. Lower radiation doses have resulted from the use of pre-patient z collimators, the availability of thin-slice axial data acquisition, the increased efficiency of ECG-based tube current modulation, and the implementation of iterative reconstruction algorithms. Faster gantry rotation and the simultaneous use of two x-ray sources have led to improvements in temporal resolution, and gains in spatial resolution have been achieved through application of the flying x-ray focal-spot technique in the z-direction. Shorter scan times have resulted from the design of detector arrays with increasing numbers of detector rows and through the simultaneous use of two x-ray sources to allow higher helical pitch. Some improvement in tissue differentiation has been achieved with dual energy CT. This article discusses these recent technical advances in detail.

  7. Agency, Socio-Cultural Context, and the Role of the Technical Communicator during IT Adoption: A Case Study in Innovation Diffusion across Cultures

    ERIC Educational Resources Information Center

    Coggio, Grace Leinbach

    2010-01-01

    This dissertation examines the diffusion of an innovative information technology system across multiple cultures between 2000 and 2006. Developed and implemented by technical communicators in the technical communication department of a global medical device company, the Advanced Single-Source Authoring and Publication System (ASAPS) brought…

  8. CARD-FISH for Environmental Microorganisms: Technical Advancement and Future Applications

    PubMed Central

    Kubota, Kengo

    2013-01-01

    Fluorescence in situ hybridization (FISH) has become a standard technique in environmental microbiology. More than 20 years have passed since this technique was first described, and it is currently used for the detection of ribosomal RNA, messenger RNA, and functional genes encoded on chromosomes. This review focuses on the advancement and applications of FISH combined with catalyzed reporter deposition (CARD, also known as tyramide signal amplification or TSA), in the detection of environmental microorganisms. Significant methodological improvements have been made in CARD-FISH technology, including its combination with other techniques and instruments. PMID:23124765

  9. Advances in environmental and occupational disorders in 2012.

    PubMed

    Peden, David B; Bush, Robert K

    2013-03-01

    The year 2012 produced a number of advances in our understanding of the effect of environmental factors on allergic diseases, identification of new allergens, immune mechanisms in host defense, factors involved in asthma severity, and therapeutic approaches. This review focuses on the articles published in the Journal in 2012 that enhance our knowledge base of environmental and occupational disorders. Identification of novel allergens can improve diagnostics, risk factor analysis can aid preventative approaches, and studies of genetic-environmental interactions and immune mechanisms will lead to better therapeutics. Copyright © 2013 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.

  10. Final Technical Report: Advanced Measurement and Analysis of PV Derate Factors.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    King, Bruce Hardison; Burton, Patrick D.; Hansen, Clifford

    2015-12-01

    The Advanced Measurement and Analysis of PV Derate Factors project focuses on improving the accuracy and reducing the uncertainty of PV performance model predictions by addressing a common element of all PV performance models referred to as “derates”. Widespread use of “rules of thumb”, combined with significant uncertainty regarding appropriate values for these factors contribute to uncertainty in projected energy production.

  11. Technical Standards and Deaf and Hard of Hearing Medical School Applicants and Students: Interrogating Sensory Capacity and Practice Capacity.

    PubMed

    Argenyi, Michael

    2016-10-01

    Applicants to medical schools who are deaf and hard of hearing (DHoH) or who have other disabilities face significant barriers to medical school admission. One commonly cited barrier to admission is medical schools' technical standards (TS) for admission, advancement, and graduation. Ethical values of diversity and equity support altering the technical standards to be more inclusive of people with disabilities. Incorporating these values into admissions, advancement, and graduation considerations for DHoH and other students with disabilities can contribute to the physician workforce being more representative of the diverse patients it serves and better able to care for them. © 2016 American Medical Association. All Rights Reserved.

  12. Exploring Strengths of Career Technical Education Deans: Implementing Change within Community Colleges

    ERIC Educational Resources Information Center

    Davis, Maria

    2013-01-01

    The purpose of this qualitative study was to explore how career technical education (CTE) deans implement crucial changes in their programs to keep up with industry standards required by external agencies, the Perkins grant, and the advancements of technology. Deans must make top-down, lateral, as well as vertical change to implement improvements…

  13. Proceedings of the 4th Annual Workshop: Advances in Smart Materials for Aerospace Applications

    NASA Technical Reports Server (NTRS)

    Hardy, Robin C. (Editor); Simpson, Joycelyn O. (Editor)

    1996-01-01

    The objective of the Fourth Annual Conference on Advances in Smart Materials for Aerospace Applications was to provide a forum for technical dialogue on numerous topics in the area of smart materials. The proceedings presented herein represent the technical contributions of the participants of the workshop. Topics addressed include shape memory alloys, ferroelectrics, fiber optics, finite element simulation, and active control.

  14. Advanced High Temperature Polymer Matrix Composites for Gas Turbine Engines Program Expansion

    NASA Technical Reports Server (NTRS)

    Hanley, David; Carella, John

    1999-01-01

    This document, submitted by AlliedSignal Engines (AE), a division of AlliedSignal Aerospace Company, presents the program final report for the Advanced High Temperature Polymer Matrix Composites for Gas Turbine Engines Program Expansion in compliance with data requirements in the statement of work, Contract No. NAS3-97003. This document includes: 1 -Technical Summary: a) Component Design, b) Manufacturing Process Selection, c) Vendor Selection, and d) Testing Validation: 2-Program Conclusion and Perspective. Also, see the Appendix at the back of this report. This report covers the program accomplishments from December 1, 1996, to August 24, 1998. The Advanced High Temperature PMC's for Gas Turbine Engines Program Expansion was a one year long, five task technical effort aimed at designing, fabricating and testing a turbine engine component using NASA's high temperature resin system AMB-21. The fiber material chosen was graphite T650-35, 3K, 8HS with UC-309 sizing. The first four tasks included component design and manufacturing, process selection, vendor selection, component fabrication and validation testing. The final task involved monthly financial and technical reports.

  15. Lincoln Advanced Science and Engineering Reinforcement (LASER) program

    NASA Technical Reports Server (NTRS)

    Williams, Willie E.

    1989-01-01

    Lincoln University, under the Lincoln Advanced Science and Engineering Reinforcement (LASER) Program, has identified and successfully recruited over 100 students for majors in technical fields. To date, over 70 percent of these students have completed or will complete technical degrees in engineering, physics, chemistry, and computer science. Of those completing the undergraduate degree, over 40 percent have gone on to graduate and professional schools. This success is attributable to well planned approaches to student recruitment, training, personal motivation, retention, and program staff. Very closely coupled to the above factors is a focus designed to achieve excellence in program services and student performance. Future contributions by the LASER Program to the pool of technical minority graduates will have a significant impact. This is already evident from the success of the students that began the first year of the program. With program plans to refine many of the already successful techniques, follow-on activities are expected to make even greater contributions to the availability of technically trained minorities. For example, undergraduate research exposure, broadened summer, and co-op work experiences will be enhanced.

  16. Technical aspects of dental CBCT: state of the art

    PubMed Central

    Araki, K; Siewerdsen, J H; Thongvigitmanee, S S

    2015-01-01

    As CBCT is widely used in dental and maxillofacial imaging, it is important for users as well as referring practitioners to understand the basic concepts of this imaging modality. This review covers the technical aspects of each part of the CBCT imaging chain. First, an overview is given of the hardware of a CBCT device. The principles of cone beam image acquisition and image reconstruction are described. Optimization of imaging protocols in CBCT is briefly discussed. Finally, basic and advanced visualization methods are illustrated. Certain topics in these review are applicable to all types of radiographic imaging (e.g. the principle and properties of an X-ray tube), others are specific for dental CBCT imaging (e.g. advanced visualization techniques). PMID:25263643

  17. Local Infrastructures for School Networking: Current Models and Prospects. Technical Report No. 22.

    ERIC Educational Resources Information Center

    Newman, Denis; And Others

    This paper identifies a paradigm shift that must take place in school networking. The ultimate goal is to retool the schools with a local technical infrastructure that gives teachers and students immediate access to communication systems and information resources, thereby supporting the implementation of advances in pedagogy and educational…

  18. Wafer hot spot identification through advanced photomask characterization techniques: part 2

    NASA Astrophysics Data System (ADS)

    Choi, Yohan; Green, Michael; Cho, Young; Ham, Young; Lin, Howard; Lan, Andy; Yang, Richer; Lung, Mike

    2017-03-01

    Historically, 1D metrics such as Mean to Target (MTT) and CD Uniformity (CDU) have been adequate for mask end users to evaluate and predict the mask impact on the wafer process. However, the wafer lithographer's process margin is shrinking at advanced nodes to a point that classical mask CD metrics are no longer adequate to gauge the mask contribution to wafer process error. For example, wafer CDU error at advanced nodes is impacted by mask factors such as 3-dimensional (3D) effects and mask pattern fidelity on sub-resolution assist features (SRAFs) used in Optical Proximity Correction (OPC) models of ever-increasing complexity. To overcome the limitation of 1D metrics, there are numerous on-going industry efforts to better define wafer-predictive metrics through both standard mask metrology and aerial CD methods. Even with these improvements, the industry continues to struggle to define useful correlative metrics that link the mask to final device performance. In part 1 of this work, we utilized advanced mask pattern characterization techniques to extract potential hot spots on the mask and link them, theoretically, to issues with final wafer performance. In this paper, part 2, we complete the work by verifying these techniques at wafer level. The test vehicle (TV) that was used for hot spot detection on the mask in part 1 will be used to expose wafers. The results will be used to verify the mask-level predictions. Finally, wafer performance with predicted and verified mask/wafer condition will be shown as the result of advanced mask characterization. The goal is to maximize mask end user yield through mask-wafer technology harmonization. This harmonization will provide the necessary feedback to determine optimum design, mask specifications, and mask-making conditions for optimal wafer process margin.

  19. Predictors of employer satisfaction: technical and non-technical skills.

    PubMed

    Danielson, Jared A; Wu, Tsui-Feng; Fales-Williams, Amanda J; Kirk, Ryan A; Preast, Vanessa A

    2012-01-01

    Employers of 2007-2009 graduates from Iowa State University College of Veterinary Medicine were asked to respond to a survey regarding their overall satisfaction with their new employees as well as their new employees' preparation in several technical and non-technical skill areas. Seventy-five responses contained complete data and were used in the analysis. Four technical skill areas (data collection, data interpretation, planning, and taking action) and five non-technical skill areas (interpersonal skills, ability to deal with legal issues, business skills, making referrals, and problem solving) were identified. All of the skill area subscales listed above had appropriate reliability (Cronbach's alpha>0.70) and were positively and significantly correlated with overall employer satisfaction. Results of two simultaneous regression analyses indicated that of the four technical skill areas, taking action is the most salient predictor of employer satisfaction. Of the five non-technical skill areas, interpersonal skills, business skills, making referrals, and problem solving were the most important skills in predicting employer satisfaction. Hierarchical regression analysis revealed that all technical skills explained 25% of the variation in employer satisfaction; non-technical skills explained an additional 42% of the variation in employer satisfaction.

  20. Advanced earth observation spacecraft computer-aided design software: Technical, user and programmer guide

    NASA Technical Reports Server (NTRS)

    Farrell, C. E.; Krauze, L. D.

    1983-01-01

    The IDEAS computer of NASA is a tool for interactive preliminary design and analysis of LSS (Large Space System). Nine analysis modules were either modified or created. These modules include the capabilities of automatic model generation, model mass properties calculation, model area calculation, nonkinematic deployment modeling, rigid-body controls analysis, RF performance prediction, subsystem properties definition, and EOS science sensor selection. For each module, a section is provided that contains technical information, user instructions, and programmer documentation.

  1. MITT writer and MITT writer advanced development: Developing authoring and training systems for complex technical domains

    NASA Technical Reports Server (NTRS)

    Wiederholt, Bradley J.; Browning, Elica J.; Norton, Jeffrey E.; Johnson, William B.

    1991-01-01

    MITT Writer is a software system for developing computer based training for complex technical domains. A training system produced by MITT Writer allows a student to learn and practice troubleshooting and diagnostic skills. The MITT (Microcomputer Intelligence for Technical Training) architecture is a reasonable approach to simulation based diagnostic training. MITT delivers training on available computing equipment, delivers challenging training and simulation scenarios, and has economical development and maintenance costs. A 15 month effort was undertaken in which the MITT Writer system was developed. A workshop was also conducted to train instructors in how to use MITT Writer. Earlier versions were used to develop an Intelligent Tutoring System for troubleshooting the Minuteman Missile Message Processing System.

  2. Bacterial identification and subtyping using DNA microarray and DNA sequencing.

    PubMed

    Al-Khaldi, Sufian F; Mossoba, Magdi M; Allard, Marc M; Lienau, E Kurt; Brown, Eric D

    2012-01-01

    The era of fast and accurate discovery of biological sequence motifs in prokaryotic and eukaryotic cells is here. The co-evolution of direct genome sequencing and DNA microarray strategies not only will identify, isotype, and serotype pathogenic bacteria, but also it will aid in the discovery of new gene functions by detecting gene expressions in different diseases and environmental conditions. Microarray bacterial identification has made great advances in working with pure and mixed bacterial samples. The technological advances have moved beyond bacterial gene expression to include bacterial identification and isotyping. Application of new tools such as mid-infrared chemical imaging improves detection of hybridization in DNA microarrays. The research in this field is promising and future work will reveal the potential of infrared technology in bacterial identification. On the other hand, DNA sequencing by using 454 pyrosequencing is so cost effective that the promise of $1,000 per bacterial genome sequence is becoming a reality. Pyrosequencing technology is a simple to use technique that can produce accurate and quantitative analysis of DNA sequences with a great speed. The deposition of massive amounts of bacterial genomic information in databanks is creating fingerprint phylogenetic analysis that will ultimately replace several technologies such as Pulsed Field Gel Electrophoresis. In this chapter, we will review (1) the use of DNA microarray using fluorescence and infrared imaging detection for identification of pathogenic bacteria, and (2) use of pyrosequencing in DNA cluster analysis to fingerprint bacterial phylogenetic trees.

  3. Identification of Chinese Herbal Medicines with Electronic Nose Technology: Applications and Challenges.

    PubMed

    Zhou, Huaying; Luo, Dehan; GholamHosseini, Hamid; Li, Zhong; He, Jiafeng

    2017-05-09

    This paper provides a review of the most recent works in machine olfaction as applied to the identification of Chinese Herbal Medicines (CHMs). Due to the wide variety of CHMs, the complexity of growing sources and the diverse specifications of herb components, the quality control of CHMs is a challenging issue. Much research has demonstrated that an electronic nose (E-nose) as an advanced machine olfaction system, can overcome this challenge through identification of the complex odors of CHMs. E-nose technology, with better usability, high sensitivity, real-time detection and non-destructive features has shown better performance in comparison with other analytical techniques such as gas chromatography-mass spectrometry (GC-MS). Although there has been immense development of E-nose techniques in other applications, there are limited reports on the application of E-noses for the quality control of CHMs. The aim of current study is to review practical implementation and advantages of E-noses for robust and effective odor identification of CHMs. It covers the use of E-nose technology to study the effects of growing regions, identification methods, production procedures and storage time on CHMs. Moreover, the challenges and applications of E-nose for CHM identification are investigated. Based on the advancement in E-nose technology, odor may become a new quantitative index for quality control of CHMs and drug discovery. It was also found that more research could be done in the area of odor standardization and odor reproduction for remote sensing.

  4. Advanced endoscopic imaging: European Society of Gastrointestinal Endoscopy (ESGE) Technology Review.

    PubMed

    East, James E; Vleugels, Jasper L; Roelandt, Philip; Bhandari, Pradeep; Bisschops, Raf; Dekker, Evelien; Hassan, Cesare; Horgan, Gareth; Kiesslich, Ralf; Longcroft-Wheaton, Gaius; Wilson, Ana; Dumonceau, Jean-Marc

    2016-11-01

    Background and aim: This technical review is an official statement of the European Society of Gastrointestinal Endoscopy (ESGE). It addresses the utilization of advanced endoscopic imaging in gastrointestinal (GI) endoscopy. Methods: This technical review is based on a systematic literature search to evaluate the evidence supporting the use of advanced endoscopic imaging throughout the GI tract. Technologies considered include narrowed-spectrum endoscopy (narrow band imaging [NBI]; flexible spectral imaging color enhancement [FICE]; i-Scan digital contrast [I-SCAN]), autofluorescence imaging (AFI), and confocal laser endomicroscopy (CLE). The Grading of Recommendations Assessment, Development and Evaluation (GRADE) system was adopted to define the strength of recommendation and the quality of evidence. Main recommendations: 1. We suggest advanced endoscopic imaging technologies improve mucosal visualization and enhance fine structural and microvascular detail. Expert endoscopic diagnosis may be improved by advanced imaging, but as yet in community-based practice no technology has been shown consistently to be diagnostically superior to current practice with high definition white light. (Low quality evidence.) 2. We recommend the use of validated classification systems to support the use of optical diagnosis with advanced endoscopic imaging in the upper and lower GI tracts (strong recommendation, moderate quality evidence). 3. We suggest that training improves performance in the use of advanced endoscopic imaging techniques and that it is a prerequisite for use in clinical practice. A learning curve exists and training alone does not guarantee sustained high performances in clinical practice. (Weak recommendation, low quality evidence.) Conclusion: Advanced endoscopic imaging can improve mucosal visualization and endoscopic diagnosis; however it requires training and the use of validated classification systems. © Georg Thieme Verlag KG Stuttgart · New York.

  5. Randomized clinical trial to evaluate mental practice in enhancing advanced laparoscopic surgical performance.

    PubMed

    Louridas, M; Bonrath, E M; Sinclair, D A; Dedy, N J; Grantcharov, T P

    2015-01-01

    Mental practice, the cognitive rehearsal of a task without physical movement, is known to enhance performance in sports and music. Investigation of this technique in surgery has been limited to basic operations. The purpose of this study was to develop mental practice scripts, and to assess their effect on advanced laparoscopic skills and surgeon stress levels in a crisis scenario. Twenty senior surgical trainees were randomized to either conventional training or mental practice groups, the latter being trained by an expert performance psychologist. Participants' skills were assessed while performing a porcine laparoscopic jejunojejunostomy as part of a crisis scenario in a simulated operating room, using the Objective Structured Assessment of Technical Skill (OSATS) and bariatric OSATS (BOSATS) instruments. Objective and subjective stress parameters were measured, as well as non-technical skills using the Non-Technical Skills for Surgeons rating tool. An improvement in OSATS (P = 0.003) and BOSATS (P = 0.003) scores was seen in the mental practice group compared with the conventional training group. Seven of ten trainees improved their technical performance during the crisis scenario, whereas four of the ten conventionally trained participants deteriorated. Mental imagery ability improved significantly following mental practice training (P = 0.011), but not in the conventional group (P = 0.083). No differences in objective or subjective stress levels or non-technical skills were evident. Mental practice improves technical performance for advanced laparoscopic tasks in the simulated operating room, and allows trainees to maintain or improve their performance despite added stress. © 2014 BJS Society Ltd. Published by John Wiley & Sons Ltd.

  6. Technological Education for the Rural Community (TERC) Project: Technical Mathematics for the Advanced Manufacturing Technician

    ERIC Educational Resources Information Center

    McCormack, Sherry L.; Zieman, Stuart

    2017-01-01

    Hopkinsville Community College's Technological Education for the Rural Community (TERC) project is funded through the National Science Foundation Advanced Technological Education (NSF ATE) division. It is advancing innovative educational pathways for technological education promoted at the community college level serving rural communities to fill…

  7. GC/IR computer-aided identification of anaerobic bacteria

    NASA Astrophysics Data System (ADS)

    Ye, Hunian; Zhang, Feng S.; Yang, Hua; Li, Zhu; Ye, Song

    1993-09-01

    A new method was developed to identify anaerobic bacteria by using pattern recognition. The method is depended on GC / JR data. The system is intended for use as a precise rapid and reproduceable aid in the identification of unknown isolates. Key Words: Anaerobic bacteria Pattern recognition Computeraided identification GC / JR 1 . TNTRODUCTTON A major problem in the field of anaerobic bacteriology is the difficulty in accurately precisely and rapidly identifying unknown isolates. Tn the proceedings of the Third International Symposium on Rapid Methods and Automation in Microbiology C. M. Moss said: " Chromatographic analysis is a new future for clinical microbiology" . 12 years past and so far it seems that this is an idea whose time has not get come but it close. Now two major advances that have brought the technology forword in terms ofmaking it appropriate for use in the clinical laboratory can aldo be cited. One is the development and implementation of fused silica capillary columns. In contrast to packed columns and those of'' greater width these columns allow reproducible recovery of hydroxey fatty acids with the same carbon chain length. The second advance is the efficient data processing afforded by modern microcomputer systems. On the other hand the practical steps for sample preparation also are an advance in the clinical laboratory. Chromatographic Analysis means mainly of analysis of fatty acids. The most common

  8. Proceedings: International Technical Communication Conference (30th, St. Louis, Missouri, May 1-4, 1983).

    ERIC Educational Resources Information Center

    Society for Technical Communication, Washington, DC.

    Prepared by representatives of government, business, industry, and education, the papers in this compilation deal with a variety of aspects of technical communication. The approximately 150 papers are arranged according to the following categories: advanced technology applications, graphics and production, management and professional development,…

  9. Advanced technology component derating

    NASA Astrophysics Data System (ADS)

    Jennings, Timothy A.

    1992-02-01

    A technical study performed to determine the derating criteria of advanced technology components is summarized. The study covered existing criteria from AFSC Pamphlet 800-27 and the development of new criteria based on data, literature searches, and the use of advanced technology prediction methods developed in RADC-TR-90-72. The devices that were investigated were as follows: VHSIC, ASIC, MIMIC, Microprocessor, PROM, Power Transistors, RF Pulse Transistors, RF Multi-Transistor Packages, Photo Diodes, Photo Transistors, Opto-Electronic Couplers, Injection Laser Diodes, LED, Hybrid Deposited Film Resistors, Chip Resistors, and Capacitors and SAW devices. The results of the study are additional derating criteria that extend the range of AFSC Pamphlet 800-27. These data will be transitioned from the report to AFSC Pamphlet 800-27 for use by government and contractor personnel in derating electronics systems yielding increased safety margins and improved system reliability.

  10. Psychometric properties of the motor diagnostics in the German football talent identification and development programme.

    PubMed

    HÖner, Oliver; Votteler, Andreas; Schmid, Markus; Schultz, Florian; Roth, Klaus

    2015-01-01

    The utilisation of motor performance tests for talent identification in youth sports is discussed intensively in talent research. This article examines the reliability, differential stability and validity of the motor diagnostics conducted nationwide by the German football talent identification and development programme and provides reference values for a standardised interpretation of the diagnostics results. Highly selected players (the top 4% of their age groups, U12-U15) took part in the diagnostics at 17 measurement points between spring 2004 and spring 2012 (N = 68,158). The heterogeneous test battery measured speed abilities and football-specific technical skills (sprint, agility, dribbling, ball control, shooting, juggling). For all measurement points, the overall score and the speed tests showed high internal consistency, high test-retest reliability and satisfying differential stability. The diagnostics demonstrated satisfying factorial-related validity with plausible and stable loadings on the two empirical factors "speed" and "technical skills". The score, and the technical skills dribbling and juggling, differentiated the most among players of different performance levels and thus showed the highest criterion-related validity. Satisfactory psychometric properties for the diagnostics are an important prerequisite for a scientifically sound rating of players' actual motor performance and for the future examination of the prognostic validity for success in adulthood.

  11. A practical guide to epidemiological practice and standards in the identification and validation of diagnostic markers using a bladder cancer example.

    PubMed

    Behrens, T; Bonberg, N; Casjens, S; Pesch, B; Brüning, T

    2014-01-01

    Technical advances to analyze biological markers have generated a plethora of promising new marker candidates for early detection of cancer. However, in subsequent analyses only few could be successfully validated as being predictive, clinically useful, or effective. This failure is partially due to rapid publication of results that were detected in early stages of biomarker research. Methodological considerations are a major concern when carrying out molecular epidemiological studies of diagnostic markers to avoid errors that increase the potential for bias. Although guidelines for conducting studies and reporting of results have been published to improve the quality of marker studies, their planning and execution still need to be improved. We will discuss different sources of bias in study design, handling of specimens, and statistical analysis to illustrate possible pitfalls associated with marker research, and present legal, ethical, and technical considerations associated with storage and handling of specimens. This article presents a guide to epidemiological standards in marker research using bladder cancer as an example. Because of the possibility to detect early cancer stages due to leakage of molecular markers from the target organ or exfoliation of tumor cells into the urine, bladder cancer is particularly useful to study diagnostic markers. To improve the overall quality of marker research, future developments should focus on networks of studies and tissue banks according to uniform legal, ethical, methodological, and technical standards. This article is part of a Special Issue entitled: Computational Proteomics in the Post-Identification Era. Guest Editors: Martin Eisenacher and Christian Stephan. © 2013.

  12. Port-of-entry Advanced Sorting System (PASS) operational test : final report

    DOT National Transportation Integrated Search

    1998-12-01

    In 1992 the Oregon Department of Transportation undertook an operational test of the Port-of-Entry Advanced Sorting System (PASS), which uses a two-way communication automatic vehicle identification system, integrated with weigh-in-motion, automatic ...

  13. Operation of the power information center: Performance of secretariat functions and information exchange activities in the advanced power field of the interagency advanced power group

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Highlights of activities conducted during the reporting period to facilitate the exchange of technical information among scientists and engineers both within the federal government and within industry are cited. Interagency Advanced Power Group meetings and special efforts, project briefs, and organization development are considered.

  14. The NOvA Technical Design Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ayres, D.S.; Drake, G.R.; Goodman, M.C.

    Technical Design Report (TDR) describes the preliminary design of the NOvA accelerator upgrades, NOvA detectors, detector halls and detector sites. Compared to the March 2006 and November 2006 NOvA Conceptual Design Reports (CDR), critical value engineering studies have been completed and the alternatives still active in the CDR have been narrowed to achieve a preliminary technical design ready for a Critical Decision 2 review. Many aspects of NOvA described this TDR are complete to a level far beyond a preliminary design. In particular, the access road to the NOvA Far Detector site in Minnesota has an advanced technical design atmore » a level appropriate for a Critical Decision 3a review. Several components of the accelerator upgrade and new neutrino detectors also have advanced technical designs appropriate for a Critical Decision 3a review. Chapter 1 is an Executive Summary with a short description of the NOvA project. Chapter 2 describes how the Fermilab NuMI beam will provide a narrow band beam of neutrinos for NOvA. Chapter 3 gives an updated overview of the scientific basis for the NOvA experiment, focusing on the primary goal to extend the search for {nu}{sub {mu}} {yields} {nu}{sub e} oscillations and measure the sin{sup 2}(2{theta}{sub 13}) parameter. This parameter has not been measured in any previous experiment and NOvA would extend the search by about an order of magnitude beyond the current limit. A secondary goal is to measure the dominant mode oscillation parameters, sin{sup 2}(2{theta}{sub 23}) and {Delta}m{sub 32}{sup 2} to a more precise level than previous experiments. Additional physics goals for NOvA are also discussed. Chapter 4 describes the Scientific Design Criteria which the Fermilab accelerator complex, NOvA detectors and NOvA detector sites must satisfy to meet the physics goals discussed in Chapter 3. Chapter 5 is an overview of the NOvA project. The changes in the design relative to the NOvA CDR are discussed. Chapter 6 summarizes

  15. Multisectoral Strategies for Advancing Girls' Education: Principles and Practice. SAGE Technical Report.

    ERIC Educational Resources Information Center

    Williams, Howard

    This paper describes issues, experiences, and strategies used in developing successful multisectoral partnerships to advance girls' education, using Guinea and Morocco as examples. Chapter 1 introduces the issue, discussing barriers to girls' education and describing the multisectoral response to interrelated barriers. Chapter 2 defines the…

  16. Reducing Manpower for a Technologically Advanced Ship

    DTIC Science & Technology

    2010-01-27

    Watchstations by 84% (119 to 34) “ Autonomic ” Fire Suppression System AFSS is designed to automatically: (1) Isolate damage to firemain piping... System (IPS) Advanced VLS Autonomic Fire Suppression Hull Form Scale Models Total Ship Computing Environment (TSCE) Integrated Undersea...Warfare (IUSW) System ( AFSS ) 8 Total Ship Organization Ship C3I Engage Support Technical Director TSCEI Sense Integrated Product Teams TSSE Director

  17. Technical Transfer Report on a TNT Enzyluminescent Vapor Detection System

    DTIC Science & Technology

    1991-02-01

    Library) ATN: DELSD-L Aberdeen Proving Ground , MD 21005 Fort Monouth, NJ 07703-5301 1 Comm er President US Army Aberden Proving Ground US Army Aation Ten...I Director, Technical Information ATTN: AMXSY-MP Defense Advanced Research Projects Agency Aberdeen Proving Ground , MD 21005-5071 1400 Wilson...Blvd.Arlington, VA 22209 1 Director US Ballistics Research Laboratory I Director ATN: AMXBR-OD-ST (STINFO) Defense Nuclear Agency Aberdeen Proving Ground , MD

  18. 4. International reservoir characterization technical conference

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1997-04-01

    This volume contains the Proceedings of the Fourth International Reservoir Characterization Technical Conference held March 2-4, 1997 in Houston, Texas. The theme for the conference was Advances in Reservoir Characterization for Effective Reservoir Management. On March 2, 1997, the DOE Class Workshop kicked off with tutorials by Dr. Steve Begg (BP Exploration) and Dr. Ganesh Thakur (Chevron). Tutorial presentations are not included in these Proceedings but may be available from the authors. The conference consisted of the following topics: data acquisition; reservoir modeling; scaling reservoir properties; and managing uncertainty. Selected papers have been processed separately for inclusion in the Energymore » Science and Technology database.« less

  19. An online ID identification system for liquefied-gas cylinder plant

    NASA Astrophysics Data System (ADS)

    He, Jin; Ding, Zhenwen; Han, Lei; Zhang, Hao

    2017-11-01

    An automatic ID identification system for gas cylinders' online production was developed based on the production conditions and requirements of the Technical Committee for Standardization of Gas Cylinders. A cylinder ID image acquisition system was designed to improve the image contrast of ID regions on gas cylinders against the background. Then the ID digits region was located by the CNN template matching algorithm. Following that, an adaptive threshold method based on the analysis of local average grey value and standard deviation was proposed to overcome defects of non-uniform background in the segmentation results. To improve the single digit identification accuracy, two BP neural networks were trained respectively for the identification of all digits and the easily confusable digits. If the single digit was classified as one of confusable digits by the former BP neural network, it was further tested by the later one, and the later result was taken as the final identification result of this single digit. At last, the majority voting was adopted to decide the final identification result for the 6-digit cylinder ID. The developed system was installed on a production line of a liquefied-petroleum-gas cylinder plant and worked in parallel with the existing weighing step on the line. Through the field test, the correct identification rate for single ID digit was 94.73%, and none of the tested 2000 cylinder ID was misclassified through the majority voting.

  20. Rapid identification of single microbes by various Raman spectroscopic techniques

    NASA Astrophysics Data System (ADS)

    Rösch, Petra; Harz, Michaela; Schmitt, Michael; Peschke, Klaus-Dieter; Ronneberger, Olaf; Burkhardt, Hans; Motzkus, Hans-Walter; Lankers, Markus; Hofer, Stefan; Thiele, Hans; Popp, Jürgen

    2006-02-01

    A fast and unambiguous identification of microorganisms is necessary not only for medical purposes but also in technical processes such as the production of pharmaceuticals. Conventional microbiological identification methods are based on the morphology and the ability of microbes to grow under different conditions on various cultivation media depending on their biochemical properties. These methods require pure cultures which need cultivation of at least 6 h but normally much longer. Recently also additional methods to identify bacteria are established e.g. mass spectroscopy, polymerase chain reaction (PCR), flow cytometry or fluorescence spectroscopy. Alternative approaches for the identification of microorganisms are vibrational spectroscopic techniques. With Raman spectroscopy a spectroscopic fingerprint of the microorganisms can be achieved. Using UV-resonance Raman spectroscopy (UVRR) macromolecules like DNA/RNA and proteins are resonantly enhanced. With an excitation wavelength of e.g. 244 nm it is possible to determine the ratio of guanine/cytosine to all DNA bases which allows a genotypic identification of microorganisms. The application of UVRR requires a large amount of microorganisms (> 10 6 cells) e.g. at least a micro colony. For the analysis of single cells micro-Raman spectroscopy with an excitation wavelength of 532 nm can be used. Here, the obtained information is from all type of molecules inside the cells which lead to a chemotaxonomic identification. In this contribution we show how wavelength dependent Raman spectroscopy yields significant molecular information applicable for the identification of microorganisms on a single cell level.

  1. Recent development of mass spectrometry and proteomics applications in identification and typing of bacteria

    PubMed Central

    Chui, Huixia; Domish, Larissa; Hernandez, Drexler; Wang, Gehua

    2016-01-01

    Identification and typing of bacteria occupy a large fraction of time and work in clinical microbiology laboratories. With the certification of some MS platforms in recent years, more applications and tests of MS‐based diagnosis methods for bacteria identification and typing have been created, not only on well‐accepted MALDI‐TOF‐MS‐based fingerprint matches, but also on solving the insufficiencies of MALDI‐TOF‐MS‐based platforms and advancing the technology to areas such as targeted MS identification and typing of bacteria, bacterial toxin identification, antibiotics susceptibility/resistance tests, and MS‐based diagnostic method development on unique bacteria such as Clostridium and Mycobacteria. This review summarizes the recent development in MS platforms and applications in bacteria identification and typing of common pathogenic bacteria. PMID:26751976

  2. International Symposium on Advanced Materials (ISAM 2013)

    NASA Astrophysics Data System (ADS)

    2014-06-01

    This proceeding is a compilation of peer reviewed papers presented at the 13th International Symposium on Advanced Materials (ISAM 2013) held from September 23-27, 2013, at Islamabad, Pakistan. In my capacity as ISAM-2013 Secretary, I feel honoured that the symposium has ended on a positive note. The ever increasing changes and intricacies that characterize modern industry necessitate a growing demand for technical information on advanced materials. ISAM and other similar forums serve to fulfill this need. The five day deliberations of ISAM 2013, consisted of 19 technical sessions and 2 poster sessions. In all, 277 papers were presented, inclusive of 80 contributory, invited and oral presentations. The symposium also hosted panel discussions led by renowned scientists and eminent researchers from foreign as well as local institutes. The ultimate aim of this proceeding is to record in writing the new findings in the field of advanced materials. I hope that the technical data available in this publication proves valuable to young scientists and researchers working in this area of science. At the same time, I wish to acknowledge Institute of Physics (IOP) Publishing UK, for accepting the research papers from ISAM-2013 for publication in the IOP Conference Series: Materials Science and Engineering. The proceeding will be available on the IOP website as an online open access document. I am profoundly thankful to the Symposium Chairman for his steadfast support and valuable guidance without which ISAM 2013 could not have been the mega event that it turned out to be. My gratitude to all our distinguished participants, session chairs/co-chairs, and reviewers for their active role in the symposium. I appreciate the entire organizing committee for the zest and ardor with which each committee fulfilled its obligations to ISAM. Last yet not the least, my thankfulness goes to all our sponsors for wilfully financing the event. Dr. Sara Qaisar Symposium Secretary Further

  3. Robotic Arm-Assisted Sonography: Review of Technical Developments and Potential Clinical Applications.

    PubMed

    Swerdlow, Daniel R; Cleary, Kevin; Wilson, Emmanuel; Azizi-Koutenaei, Bamshad; Monfaredi, Reza

    2017-04-01

    Ultrasound imaging requires trained personnel. Advances in robotics and data transmission create the possibility of telesonography. This review introduces clinicians to current technical work in and potential applications of this developing capability. Telesonography offers advantages in hazardous or remote environments. Robotically assisted ultrasound can reduce stress injuries in sonographers and has potential utility during robotic surgery and interventional procedures.

  4. A journey into the technical evolution of neuroendoscopy.

    PubMed

    Di Ieva, Antonio; Tam, Mallorie; Tschabitscher, Manfred; Cusimano, Michael D

    2014-12-01

    Neuroendoscopy has become a well-accepted technique in neurosurgery. After the introduction of the endoscope in medical practice by Phillip Bozzini in 1806, influential individuals such as Harold Hopkins and Karl Storz paved the way for its current success. With the present pace of technologic advancements, great improvement in the instrumentation is expected along with the status of neuroendoscopy in the neurosurgical field. Specific attention is given to the history of the development of the endoscope, while also discussing more recent advances dating from 1990 onward. The importance of each development for the purpose of the instrument is explained. Gaps in the literature regarding the technical aspects of neuroendoscopy, including the optical physics in the endoscope, three-dimensional endoscopy, and clinical applications of neuroendoscopy and robotics, are addressed. Copyright © 2014 Elsevier Inc. All rights reserved.

  5. Advances in Preventing Childhood and Adolescent Problem Behavior

    ERIC Educational Resources Information Center

    Jenson, Jeffrey M.

    2010-01-01

    Recent advances in the field of prevention have led to a deeper understanding of the causes of adolescent problem behavior and to the identification of efficacious strategies to prevent delinquency, drug use, and other antisocial conduct. This 2009 Aaron Rosen lecture to members of the "Society for Social Work and Research" traces the evolution of…

  6. Advanced space program studies. Overall executive summary

    NASA Technical Reports Server (NTRS)

    Wolfe, M. G.

    1977-01-01

    NASA and DoD requirements and planning data were used in multidiscipline advanced planning investigations of space operations and associated elements (including man), identification of potential low cost approaches, vehicle design, cost synthesis techniques, technology forecasting and opportunities for DoD technology transfer, and the development near-, mid-, and far-term space initiatives and development plans with emphasis on domestic and military commonality. An overview of objectives and results are presented for the following studies: advanced space planning and conceptual analysis, shuttle users, technology assessment and new opportunities, standardization and program practice, integrated STS operations planning, solid spinning upper stage, and integrated planning support functions.

  7. Advanced fuels campaign 2013 accomplishments

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Braase, Lori; Hamelin, Doug

    The mission of the Advanced Fuels Campaign (AFC) is to perform Research, Development, and Demonstration (RD&D) activities for advanced fuel forms (including cladding) to enhance the performance and safety of the nation’s current and future reactors; enhance proliferation resistance of nuclear fuel; effectively utilize nuclear energy resources; and address the longer-term waste management challenges. This includes development of a state-of-the art Research and Development (R&D) infrastructure to support the use of “goal-oriented science-based approach.” In support of the Fuel Cycle Research and Development (FCRD) program, AFC is responsible for developing advanced fuels technologies to support the various fuel cycle optionsmore » defined in the Department of Energy (DOE) Nuclear Energy Research and Development Roadmap, Report to Congress, April 2010. Accomplishments made during fiscal year (FY) 2013 are highlighted in this report, which focuses on completed work and results. The process details leading up to the results are not included; however, the technical contact is provided for each section.« less

  8. Teacher Collaborative Curriculum Design in Technical Vocational Colleges: A Strategy for Maintaining Curriculum Consistency?

    ERIC Educational Resources Information Center

    Albashiry, Nabeel M.; Voogt, Joke M.; Pieters, Jules M.

    2015-01-01

    The Technical Vocational Education and Training (TVET) curriculum requires continuous renewal and constant involvement of stakeholders in the redesign process. Due to a lack of curriculum design expertise, TVET institutions in developing contexts encounter challenges maintaining and advancing the quality and relevance of their programmes to the…

  9. The Air Force Advanced Instructional System (AIS): An Overview.

    ERIC Educational Resources Information Center

    Yasutake, Joseph Y.; Stobie, William H.

    The Air Force Advanced Instructional System (AIS) is a prototype computer-based multimedia system for the administration and management of individualized technical training on a large scale. The paper provides an overview of the AIS: (1) its purposes and goals, (2) the background and rationale for the development approach, (3) a basic description…

  10. Technical Reference Suite Addressing Challenges of Providing Assurance for Fault Management Architectural Design

    NASA Technical Reports Server (NTRS)

    Fitz, Rhonda; Whitman, Gerek

    2016-01-01

    Research into complexities of software systems Fault Management (FM) and how architectural design decisions affect safety, preservation of assets, and maintenance of desired system functionality has coalesced into a technical reference (TR) suite that advances the provision of safety and mission assurance. The NASA Independent Verification and Validation (IV&V) Program, with Software Assurance Research Program support, extracted FM architectures across the IV&V portfolio to evaluate robustness, assess visibility for validation and test, and define software assurance methods applied to the architectures and designs. This investigation spanned IV&V projects with seven different primary developers, a wide range of sizes and complexities, and encompassed Deep Space Robotic, Human Spaceflight, and Earth Orbiter mission FM architectures. The initiative continues with an expansion of the TR suite to include Launch Vehicles, adding the benefit of investigating differences intrinsic to model-based FM architectures and insight into complexities of FM within an Agile software development environment, in order to improve awareness of how nontraditional processes affect FM architectural design and system health management. The identification of particular FM architectures, visibility, and associated IV&V techniques provides a TR suite that enables greater assurance that critical software systems will adequately protect against faults and respond to adverse conditions. Additionally, the role FM has with regard to strengthened security requirements, with potential to advance overall asset protection of flight software systems, is being addressed with the development of an adverse conditions database encompassing flight software vulnerabilities. Capitalizing on the established framework, this TR suite provides assurance capability for a variety of FM architectures and varied development approaches. Research results are being disseminated across NASA, other agencies, and the

  11. The state of advanced measurement and verification technology and industry application

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Granderson, Jessica; Fernandes, Samuel

    2017-09-28

    With the expansion of advanced metering and increased use of energy analytics tools, the energy efficiency community has begun to explore the application of advanced measurement and verification (or ‘M & V 2.0') technologies. Current literature recognizes their promise, but does not offer in-depth assessment of technical underpinnings. Here, this paper assesses the state of the technology and its application. Sixteen commercially available technologies were characterized and combined with a national review of their use.

  12. Fundamental Aeronautics Program: Overview of Propulsion Work in the Supersonic Cruise Efficiency Technical Challenge

    NASA Technical Reports Server (NTRS)

    Castner, Ray

    2012-01-01

    The Supersonics Project, part of NASA's Fundamental Aeronautics Program, contains a number of technical challenge areas which include sonic boom community response, airport noise, high altitude emissions, cruise efficiency, light weight durable engines/airframes, and integrated multi-discipline system design. This presentation provides an overview of the current (2012) activities in the supersonic cruise efficiency technical challenge, and is focused specifically on propulsion technologies. The intent is to develop and validate high-performance supersonic inlet and nozzle technologies. Additional work is planned for design and analysis tools for highly-integrated low-noise, low-boom applications. If successful, the payoffs include improved technologies and tools for optimized propulsion systems, propulsion technologies for a minimized sonic boom signature, and a balanced approach to meeting efficiency and community noise goals. In this propulsion area, the work is divided into advanced supersonic inlet concepts, advanced supersonic nozzle concepts, low fidelity computational tool development, high fidelity computational tools, and improved sensors and measurement capability. The current work in each area is summarized.

  13. 78 FR 14084 - Request for Information To Gather Technical Expertise Pertaining to the Identification and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-04

    ... Native American students, as English learners. For these reasons this RFI seeks solutions; advice... Expertise Pertaining to the Identification and Placement of Native American Students Who Are English... students in grades K-12 as English learners and to appropriately place these students in language...

  14. TOXICITY IDENTIFICATION EVALUATION WORKSHOP-PART II: WHAT WORKS, WHAT DOESN'T, AND DEVELOPMENTS FOR EFFLUENTS AND AQUEOUS MEDIA

    EPA Science Inventory

    Toxicity reduction evaluations (TRE) and Toxicity Identification Evaluations (TIE) case examples were the basis of a technical workshop held by SETAC. Techniques to evaluate the mixtures of toxicants by using acute and chronic toxicity endpoints that incorporate marine, estuarine...

  15. On the Horizon: New Advances in Security Technology

    ERIC Educational Resources Information Center

    Gamble, Cheryl

    2005-01-01

    The worlds of security and technology have been on an intersecting course since the first published account of the use of fingerprint identification made news in 1880 (although unpublished reports suggest its use as early as 1858). In the three and one half years since the September 11 attacks, technological advances across the security field have…

  16. Identification of cost effective energy conservation measures

    NASA Technical Reports Server (NTRS)

    Bierenbaum, H. S.; Boggs, W. H.

    1978-01-01

    In addition to a successful program of readily implemented conservation actions for reducing building energy consumption at Kennedy Space Center, recent detailed analyses have identified further substantial savings for buildings representative of technical facilities designed when energy costs were low. The techniques employed for determination of these energy savings consisted of facility configuration analysis, power and lighting measurements, detailed computer simulations and simulation verifications. Use of these methods resulted in identification of projected energy savings as large as $330,000 a year (approximately two year break-even period) in a single building. Application of these techniques to other commercial buildings is discussed

  17. An overview of the NASA Advanced Propulsion Concepts program

    NASA Technical Reports Server (NTRS)

    Curran, Francis M.; Bennett, Gary L.; Frisbee, Robert H.; Sercel, Joel C.; Lapointe, Michael R.

    1992-01-01

    NASA Advanced Propulsion Concepts (APC) program for the development of long-term space propulsion system schemes is managed by both NASA-Lewis and the JPL and is tasked with the identification and conceptual development of high-risk/high-payoff configurations. Both theoretical and experimental investigations have been undertaken in technology areas deemed essential to the implementation of candidate concepts. These APC candidates encompass very high energy density chemical propulsion systems, advanced electric propulsion systems, and an antiproton-catalyzed nuclear propulsion concept. A development status evaluation is presented for these systems.

  18. Identification of granite varieties from colour spectrum data.

    PubMed

    Araújo, María; Martínez, Javier; Ordóñez, Celestino; Vilán, José Antonio

    2010-01-01

    The granite processing sector of the northwest of Spain handles many varieties of granite with specific technical and aesthetic properties that command different prices in the natural stone market. Hence, correct granite identification and classification from the outset of processing to the end-product stage optimizes the management and control of stocks of granite slabs and tiles and facilitates the operation of traceability systems. We describe a methodology for automatically identifying granite varieties by processing spectral information captured by a spectrophotometer at various stages of processing using functional machine learning techniques.

  19. Identification of Granite Varieties from Colour Spectrum Data

    PubMed Central

    Araújo, María; Martínez, Javier; Ordóñez, Celestino; Vilán, José Antonio

    2010-01-01

    The granite processing sector of the northwest of Spain handles many varieties of granite with specific technical and aesthetic properties that command different prices in the natural stone market. Hence, correct granite identification and classification from the outset of processing to the end-product stage optimizes the management and control of stocks of granite slabs and tiles and facilitates the operation of traceability systems. We describe a methodology for automatically identifying granite varieties by processing spectral information captured by a spectrophotometer at various stages of processing using functional machine learning techniques. PMID:22163673

  20. Advanced composite elevator for Boeing 727 aircraft. Volume 1: Technical summary

    NASA Technical Reports Server (NTRS)

    Chovil, D. V.; Harvey, S. T.; Mccarty, J. E.; Desper, O. E.; Jamison, E. S.; Syder, H.

    1981-01-01

    The design, development, analysis, and testing activities and results that were required to produce five and one-half shipsets of advanced composite elevators for Boeing 727 aircraft are summarized. During the preliminary design period, alternative concepts were developed. After selection of the best design, detail design and basic configuration improvements were evaluated. Five and one-half shipsets were manufactured. All program goals (except competitive cost demonstration) were accomplished when our design met or exceeded all requirements, criteria, and objectives.

  1. Advanced Avionic Systems for Multimission Applications. Volume I.

    DTIC Science & Technology

    1982-10-01

    technical report are theoretical and in no way reflect Air Fortp-nwnpid qnftwRrp png ramc 19. KEY WORDS (Continue on reveree aide It neceeary and Identify...addressed (1) the Development & Evaluation of Advanced Digital Avionics System Architectures and (2) the Development of a Single Processor Synchronous...29 4.3.2 Memory Technologies . . . . . . . . . . . . . . . . . 30 4.3.3 BIU Technology . . . . . . . . . . . . . . . . . . . 33

  2. Advanced Controller for the Free-Piston Stirling Convertor

    NASA Technical Reports Server (NTRS)

    Gerber, Scott S.; Jamison, Mike; Roth, Mary Ellen; Regan, Timothy F.

    2004-01-01

    The free-piston Stirling power convertor is being considered as an advanced power conversion technology to be used for future NASA deep space missions requiring long life radioisotope power systems. This technology has a conversion efficiency of over 25%, which is significantly higher than the efficiency of the Radioisotope Thermal-electric Generators (RTG) now in use. The NASA Glenn Research Center has long been recognized as a leader in Stirling technology and is responsible for the development of advanced technologies that are intended to significantly improve key characteristics of the Stirling convertor. The advanced technologies identified for development also consider the requirements of potential future missions and the new capabilities that have become available in the associated technical areas. One of the key areas identified for technology development is the engine controller. To support this activity, an advanced controller is being developed for the Stirling power convertor. This controller utilizes active power factor correction electronics and microcontroller-based controls. The object of this paper is to present an overview of the advanced controller concept with modeling, simulation and hardware test data.

  3. [Identification of mycobacteria to the species level by molecular methods in the Public Health Laboratory of Bogotá, Colombia].

    PubMed

    Hernández-Toloza, Johana Esther; Rincón-Serrano, María de Pilar; Celis-Bustos, Yamile Adriana; Aguillón, Claudia Inés

    2016-01-01

    Global epidemiology of non-tuberculous mycobacteria (NTM) is unknown due to the fact that notification is not required in many countries, however the number of infection reports and outbreaks caused by NTM suggest a significant increase in the last years. Traditionally, mycobacteria identification is made through biochemical profiles which allow to differentiate M. tuberculosis from NTM, and in some cases the mycobacteria species. Nevertheless, these methods are technically cumbersome and time consuming. On the other hand, the introduction of methods based on molecular biology has improved the laboratory diagnosis of NTM. To establish the NTM frequency in positive cultures for acid-fast bacilli (AAFB) which were sent to Laboratorio de Salud Pública de Bogotá over a 12 month period. A total of 100 positive cultures for acid-fast bacilli from public and private hospitals from Bogotá were identified by both biochemical methods and the molecular methods PRA (PCR-restriction enzyme analysis) and multiplex-PCR. Furthermore, low prevalence mycobacteria species and non-interpretable results were confirmed by 16SrDNA sequentiation analysis. Identification using the PRA method showed NMT occurrence in 11% of cultures. In addition, this molecular methodology allowed to detect the occurrence of more than one mycobacteria in 4% of the cultures. Interestingly, a new M. kubicae pattern of PCR-restriction analysis is reported in our study. Using a mycobacteria identification algorithm, which includes the molecular method PRA, improves the diagnostic power of conventional methods and could help to advance both NTM epidemiology knowledge and mycobacteriosis control. Copyright © 2015 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  4. New technology implementation: Technical, economic and political factors

    NASA Technical Reports Server (NTRS)

    Dean, J. W., Jr.; Susman, G. I.; Porter, P. S.

    1985-01-01

    An analysis is presented of the process of implementing advanced manufacturing technology, based on studies of numerous organizations. This process is seen as consisting of a series of decisions with technical, economic, and political objectives. Frequency decisions involve specifications, equipment, resources/organization, and location. Problems in implementation are viewed as resulting from tradeoffs among the objectives, the tendency of decision makers to emphasize some objectives at the expense of others, and the propensity of problems to spread from one area to another. Three sets of recommendations, based on this analysis, are presented.

  5. Identification procedure for epistemic uncertainties using inverse fuzzy arithmetic

    NASA Astrophysics Data System (ADS)

    Haag, T.; Herrmann, J.; Hanss, M.

    2010-10-01

    For the mathematical representation of systems with epistemic uncertainties, arising, for example, from simplifications in the modeling procedure, models with fuzzy-valued parameters prove to be a suitable and promising approach. In practice, however, the determination of these parameters turns out to be a non-trivial problem. The identification procedure to appropriately update these parameters on the basis of a reference output (measurement or output of an advanced model) requires the solution of an inverse problem. Against this background, an inverse method for the computation of the fuzzy-valued parameters of a model with epistemic uncertainties is presented. This method stands out due to the fact that it only uses feedforward simulations of the model, based on the transformation method of fuzzy arithmetic, along with the reference output. An inversion of the system equations is not necessary. The advancement of the method presented in this paper consists of the identification of multiple input parameters based on a single reference output or measurement. An optimization is used to solve the resulting underdetermined problems by minimizing the uncertainty of the identified parameters. Regions where the identification procedure is reliable are determined by the computation of a feasibility criterion which is also based on the output data of the transformation method only. For a frequency response function of a mechanical system, this criterion allows a restriction of the identification process to some special range of frequency where its solution can be guaranteed. Finally, the practicability of the method is demonstrated by covering the measured output of a fluid-filled piping system by the corresponding uncertain FE model in a conservative way.

  6. Image formation in diffusion MRI: A review of recent technical developments

    PubMed Central

    Miller, Karla L.

    2017-01-01

    Diffusion magnetic resonance imaging (MRI) is a standard imaging tool in clinical neurology, and is becoming increasingly important for neuroscience studies due to its ability to depict complex neuroanatomy (eg, white matter connectivity). Single‐shot echo‐planar imaging is currently the predominant formation method for diffusion MRI, but suffers from blurring, distortion, and low spatial resolution. A number of methods have been proposed to address these limitations and improve diffusion MRI acquisition. Here, the recent technical developments for image formation in diffusion MRI are reviewed. We discuss three areas of advance in diffusion MRI: improving image fidelity, accelerating acquisition, and increasing the signal‐to‐noise ratio. Level of Evidence: 5 Technical Efficacy: Stage 1 J. MAGN. RESON. IMAGING 2017;46:646–662 PMID:28194821

  7. Identification of Chinese Herbal Medicines with Electronic Nose Technology: Applications and Challenges

    PubMed Central

    Zhou, Huaying; Luo, Dehan; GholamHosseini, Hamid; Li, Zhong; He, Jiafeng

    2017-01-01

    This paper provides a review of the most recent works in machine olfaction as applied to the identification of Chinese Herbal Medicines (CHMs). Due to the wide variety of CHMs, the complexity of growing sources and the diverse specifications of herb components, the quality control of CHMs is a challenging issue. Much research has demonstrated that an electronic nose (E-nose) as an advanced machine olfaction system, can overcome this challenge through identification of the complex odors of CHMs. E-nose technology, with better usability, high sensitivity, real-time detection and non-destructive features has shown better performance in comparison with other analytical techniques such as gas chromatography-mass spectrometry (GC-MS). Although there has been immense development of E-nose techniques in other applications, there are limited reports on the application of E-noses for the quality control of CHMs. The aim of current study is to review practical implementation and advantages of E-noses for robust and effective odor identification of CHMs. It covers the use of E-nose technology to study the effects of growing regions, identification methods, production procedures and storage time on CHMs. Moreover, the challenges and applications of E-nose for CHM identification are investigated. Based on the advancement in E-nose technology, odor may become a new quantitative index for quality control of CHMs and drug discovery. It was also found that more research could be done in the area of odor standardization and odor reproduction for remote sensing. PMID:28486407

  8. Open-Source Integrated Design-Analysis Environment For Nuclear Energy Advanced Modeling & Simulation Final Scientific/Technical Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    O'Leary, Patrick

    The framework created through the Open-Source Integrated Design-Analysis Environment (IDAE) for Nuclear Energy Advanced Modeling & Simulation grant has simplify and democratize advanced modeling and simulation in the nuclear energy industry that works on a range of nuclear engineering applications. It leverages millions of investment dollars from the Department of Energy's Office of Nuclear Energy for modeling and simulation of light water reactors and the Office of Nuclear Energy's research and development. The IDEA framework enhanced Kitware’s Computational Model Builder (CMB) while leveraging existing open-source toolkits and creating a graphical end-to-end umbrella guiding end-users and developers through the nuclear energymore » advanced modeling and simulation lifecycle. In addition, the work deliver strategic advancements in meshing and visualization for ensembles.« less

  9. A study on the utilization of advanced composites in commercial aircraft wing structure

    NASA Technical Reports Server (NTRS)

    Watts, D. J.

    1978-01-01

    A study was conducted to define the technology and data needed to support the introduction of advanced composite materials in the wing structure of future production aircraft. The study accomplished the following: (1) definition of acceptance factors, (2) identification of technology issues, (3) evaluation of six candidate wing structures, (4) evaluation of five program options, (5) definition of a composite wing technology development plan, (6) identification of full-scale tests, (7) estimation of program costs for the total development plan, (8) forecast of future utilization of composites in commercial transport aircraft and (9) identification of critical technologies for timely program planning.

  10. Evaluation of the Anaheim Advanced Traffic Control System Field Operational Test : executive summary

    DOT National Transportation Integrated Search

    1999-07-01

    This Executive Summary provides an overview of the technical and institutional issues associated with the evaluation of the federally-sponsored Anaheim Advanced Traffic Control : System Field Operations Test. The primary FOT objective was the impleme...

  11. Remaining Technical Challenges and Future Plans for Oil-Free Turbomachinery

    NASA Technical Reports Server (NTRS)

    DellaCorte, Christopher; Bruckner, Robert J.

    2010-01-01

    The application of Oil-Free technologies (foil gas bearings, solid lubricants and advanced analysis and predictive modeling tools) to advanced turbomachinery has been underway for several decades. During that time, full commercialization has occurred in aircraft air cycle machines, turbocompressors and cryocoolers and ever-larger microturbines. Emerging products in the automotive sector (turbochargers and superchargers) indicate that high volume serial production of foil bearings is imminent. Demonstration of foil bearings in APU s and select locations in propulsion gas turbines illustrates that such technology also has a place in these future systems. Foil bearing designs, predictive tools and advanced solid lubricants have been reported that can satisfy anticipated requirements but a major question remains regarding the scalability of foil bearings to ever larger sizes to support heavier rotors. In this paper, the technological history, primary physics, engineering practicalities and existing experimental and experiential database for scaling foil bearings are reviewed and the major remaining technical challenges are identified.

  12. An approach to knowledge structuring for advanced phases of the Technical and Management Information System (TMIS)

    NASA Technical Reports Server (NTRS)

    Goranson, H. T.

    1986-01-01

    The Technical and Management Information System (TMIS) must employ on enlightened approach to its object structure, but basic issues in conceptual structuring remain to be resolved. Sirius outlines the necessary agenda and reports on progress toward solutions.

  13. AGT (Advanced Gas Turbine) technology project

    NASA Technical Reports Server (NTRS)

    1988-01-01

    An overall summary documentation is provided for the Advanced Gas Turbine Technology Project conducted by the Allison Gas Turbine Division of General Motors. This advanced, high risk work was initiated in October 1979 under charter from the U.S. Congress to promote an engine for transportation that would provide an alternate to reciprocating spark ignition (SI) engines for the U.S. automotive industry and simultaneously establish the feasibility of advanced ceramic materials for hot section components to be used in an automotive gas turbine. As this program evolved, dictates of available funding, Government charter, and technical developments caused program emphases to focus on the development and demonstration of the ceramic turbine hot section and away from the development of engine and powertrain technologies and subsequent vehicular demonstrations. Program technical performance concluded in June 1987. The AGT 100 program successfully achieved project objectives with significant technology advances. Specific AGT 100 program achievements are: (1) Ceramic component feasibility for use in gas turbine engines has been demonstrated; (2) A new, 100 hp engine was designed, fabricated, and tested for 572 hour at operating temperatures to 2200 F, uncooled; (3) Statistical design methodology has been applied and correlated to experimental data acquired from over 5500 hour of rig and engine testing; (4) Ceramic component processing capability has progressed from a rudimentary level able to fabricate simple parts to a sophisticated level able to provide complex geometries such as rotors and scrolls; (5) Required improvements for monolithic and composite ceramic gas turbine components to meet automotive reliability, performance, and cost goals have been identified; (6) The combustor design demonstrated lower emissions than 1986 Federal Standards on methanol, JP-5, and diesel fuel. Thus, the potential for meeting emission standards and multifuel capability has been initiated

  14. Proceedings of the Workshop on Identification and Control of Flexible Space Structures, volume 1

    NASA Technical Reports Server (NTRS)

    Rodriguez, G. (Editor)

    1985-01-01

    Identification and control of flexible space structures were studied. Exploration of the most advanced modeling estimation, identification and control methodologies to flexible space structures was discussed. The following general areas were discussed: space platforms, antennas, and flight experiments; control/structure interactions - modeling, integrated design and optimization, control and stabilization, and shape control; control technology; control of space stations; large antenna control, dynamics and control experiments, and control/structure interaction experiments.

  15. Advancing the field of 3D biomaterial printing.

    PubMed

    Jakus, Adam E; Rutz, Alexandra L; Shah, Ramille N

    2016-01-11

    3D biomaterial printing has emerged as a potentially revolutionary technology, promising to transform both research and medical therapeutics. Although there has been recent progress in the field, on-demand fabrication of functional and transplantable tissues and organs is still a distant reality. To advance to this point, there are two major technical challenges that must be overcome. The first is expanding upon the limited variety of available 3D printable biomaterials (biomaterial inks), which currently do not adequately represent the physical, chemical, and biological complexity and diversity of tissues and organs within the human body. Newly developed biomaterial inks and the resulting 3D printed constructs must meet numerous interdependent requirements, including those that lead to optimal printing, structural, and biological outcomes. The second challenge is developing and implementing comprehensive biomaterial ink and printed structure characterization combined with in vitro and in vivo tissue- and organ-specific evaluation. This perspective outlines considerations for addressing these technical hurdles that, once overcome, will facilitate rapid advancement of 3D biomaterial printing as an indispensable tool for both investigating complex tissue and organ morphogenesis and for developing functional devices for a variety of diagnostic and regenerative medicine applications.

  16. A Modernization Plan for the Technical Data Department of the Naval Ships Weapon Systems Engineering Station

    DTIC Science & Technology

    1976-09-01

    technology has made possible the deployment of very sophisticated and highly capable weapon systems. Taking advantage of this technology has carried...3) Ancillary Equipment 208 Types Numerous Notes : 1. Number of ships with this system 2. Includes Tartar used only for surface capability 3. These...maintains the Configuration Item Identification File (CIIF) . The CIIF provides storage and retrieval capability for technical and logistics data specified on

  17. 19 CFR 181.93 - Submission of advance ruling requests.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... commercial, common, or technical designation of the good or material; if the good or material is composed of... name of the port or place at which any good involved in the transaction will be imported or which will... ruling. Where the request for an advance ruling is submitted by or on behalf of the importer of the good...

  18. 19 CFR 181.93 - Submission of advance ruling requests.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... commercial, common, or technical designation of the good or material; if the good or material is composed of... name of the port or place at which any good involved in the transaction will be imported or which will... ruling. Where the request for an advance ruling is submitted by or on behalf of the importer of the good...

  19. Performance and technical feasibility comparison of reusable launch systems: A synthesis of the ESA winged launcher studies

    NASA Astrophysics Data System (ADS)

    Berry, W.; Grallert, H.

    1996-02-01

    The paper presents a synthesis of the performance and technical feasibility assessment of 7 reusable launcher types, comprising 13 different vehicles, studied by European Industry for ESA in the ESA Winged Launcher Study in the period January 1988 to May 1994. The vehicles comprised single-stage-to-orbit (SSTO) and two-stage-to-orbit (TSTO) vehicles, propelled by either air-breathing/rocket propulsion or entirely by rocket propulsion. The results showed that an SSTO vehicle of the HOTOL-type, propelled by subsonic combustion air-breathing/rocket engines could barely deliver the specified payload mass and was aerodynamically unstable; that a TSTO vehicle of the Saenger type, employing subsonic combustion airbreathing propulsion in its first stage and rocket propulsion in its second stage, could readily deliver the specified payload mass and was found to be technically feasible and versatile; that an SSTO vehicle of the NASP type, propelled by supersonic combustion airbreathing/rocket propulsion was able to deliver a reduced payload mass, was very complex and required very advanced technologies; that an air-launched rocket propelled vehicle of the Interim HOTOL type, although technically feasible, could deliver only a reduced payload mass, being constrained by the lifting capability of the carrier airplane; that three different, entirely rocket-propelled vehicles could deliver the specified payload mass, were technically feasible but required relatively advanced technologies.

  20. Evoking and Measuring Identification with Narrative Characters - A Linguistic Cues Framework.

    PubMed

    van Krieken, Kobie; Hoeken, Hans; Sanders, José

    2017-01-01

    Current research on identification with narrative characters poses two problems. First, although identification is seen as a dynamic process of which the intensity varies during reading, it is usually measured by means of post-reading questionnaires containing self-report items. Second, it is not clear which linguistic characteristics evoke identification. The present paper proposes that an interdisciplinary framework allows for more precise manipulations and measurements of identification, which will ultimately advance our understanding of the antecedents and nature of this process. The central hypothesis of our Linguistic Cues Framework is that identification with a narrative character is a multidimensional experience for which different dimensions are evoked by different linguistic cues. The first part of the paper presents a literature review on identification, resulting in a renewed conceptualization of identification which distinguishes six dimensions: a spatiotemporal, a perceptual, a cognitive, a moral, an emotional, and an embodied dimension. The second part argues that each of these dimensions is influenced by specific linguistic cues which represent various aspects of the narrative character's perspective. The proposed relations between linguistic cues and identification dimensions are specified in six propositions. The third part discusses what psychological and neurocognitive methods enable the measurement of the various identification dimensions in order to test the propositions. By establishing explicit connections between the linguistic characteristics of narratives and readers' physical, psychological, and neurocognitive responses to narratives, this paper develops a research agenda for future empirical research on identification with narrative characters.

  1. Early identification of cervical neoplasia with Raman spectroscopy and advanced methods for biomedical applications

    NASA Astrophysics Data System (ADS)

    Jess, Phillip R. T.; Smith, Daniel D. W.; Mazilu, Michael; Cormack, Iain; Riches, Andrew C.; Herrington, C. Simon; Dholakia, Kishan

    2008-02-01

    Early detection of malignant tumours, or their precursor lesions, can dramatically improve patient outcome. High risk human Papillomavirus (HPV), particularly HPV16, infection can lead to the initiation and development of uterine cervical neoplasia. Bearing this in mind the identification of the effects of HPV infection may have clinical value. In this manuscript we investigate the application of Raman microspectroscopy to detect the presence of HPV in cultured cells when compared with normal cells. We also investigate the effect of sample fixation, which is a common clinical practice, on the ability of Raman spectroscopy to detect the presence of HPV. Raman spectra were acquired from Primary Human Keratinocytes (PHK), PHK expressing the E7 gene of HPV 16 (PHK E7) and CaSki cells, an HPV16 containing cervical carcinoma derived cell line. The average Raman spectra display variations, mostly in peaks relating to DNA and proteins, consistent with HPV gene expression and the onset of neoplasia in both live and fixed samples. Principle component analysis was used to objectively discriminate between the cells types giving sensitivities up to 100% for the comparison between PHK and CaSki. These results show that Raman spectroscopy can discriminate between cell lines representing different stages of cervical neoplasia. Furthermore Raman spectroscopy was able to identify cells expressing the HPV 16 E7 gene suggesting the approach may be of value in clinical practice. Finally this technique was also able to detect the effects of the virus in fixed samples demonstrating the compatibility of this technique with current cervical screening methods. However if Raman spectroscopy is to make a significant impact in clinical practice the long acquisition times must be addressed. In this report we examine the potential for beam shaping and advanced to improve the signal to noise ration hence subsequently facilitating a reduction in acquisition time.

  2. Advances in miniature spectrometer and sensor development

    NASA Astrophysics Data System (ADS)

    Malinen, Jouko; Rissanen, Anna; Saari, Heikki; Karioja, Pentti; Karppinen, Mikko; Aalto, Timo; Tukkiniemi, Kari

    2014-05-01

    Miniaturization and cost reduction of spectrometer and sensor technologies has great potential to open up new applications areas and business opportunities for analytical technology in hand held, mobile and on-line applications. Advances in microfabrication have resulted in high-performance MEMS and MOEMS devices for spectrometer applications. Many other enabling technologies are useful for miniature analytical solutions, such as silicon photonics, nanoimprint lithography (NIL), system-on-chip, system-on-package techniques for integration of electronics and photonics, 3D printing, powerful embedded computing platforms, networked solutions as well as advances in chemometrics modeling. This paper will summarize recent work on spectrometer and sensor miniaturization at VTT Technical Research Centre of Finland. Fabry-Perot interferometer (FPI) tunable filter technology has been developed in two technical versions: Piezoactuated FPIs have been applied in miniature hyperspectral imaging needs in light weight UAV and nanosatellite applications, chemical imaging as well as medical applications. Microfabricated MOEMS FPIs have been developed as cost-effective sensor platforms for visible, NIR and IR applications. Further examples of sensor miniaturization will be discussed, including system-on-package sensor head for mid-IR gas analyzer, roll-to-roll printed Surface Enhanced Raman Scattering (SERS) technology as well as UV imprinted waveguide sensor for formaldehyde detection.

  3. Phenotypic Identification of Actinomyces and Related Species Isolated from Human Sources

    PubMed Central

    Sarkonen, Nanna; Könönen, Eija; Summanen, Paula; Könönen, Mauno; Jousimies-Somer, Hannele

    2001-01-01

    Recent advancements in chemotaxonomic and molecular biology-based identification methods have clarified the taxonomy of the genus Actinomyces and have led to the recognition of several new Actinomyces and related species. Actinomyces-like gram-positive rods have increasingly been isolated from various clinical specimens. Thus, an easily accessible scheme for reliable differentiation at the species level is needed in clinical and oral microbiology laboratories, where bacterial identification is mainly based on conventional biochemical methods. In the present study we designed a two-step protocol that consists of a flowchart that describes rapid, cost-efficient tests for preliminary identification of Actinomyces and closely related species and an updated more comprehensive scheme that also uses fermentation reactions for accurate differentiation of Actinomyces and closely related species. PMID:11682514

  4. 'Missing persons': technical terminology as a barrier in psychiatry.

    PubMed

    Clarke, Ciaran

    2012-02-01

    Several fields contributing to psychiatric advances, such as psychology, biology, and the humanities, have not yet met to produce a cohesive and integrated picture of human function and dysfunction, strength and vulnerability, etc., despite advances in their own areas. The failure may have its roots in a disagreement on what we mean by the human person and his or her relationship with the world, for which the incommensurate language of these disciplines may be partly to blame. Turns taken by western philosophy over the past 400 years may help to explain this. Language is such an important tool for psychiatrists, that examination of it may afford an insight into the reasons for divisions in the field. This paper aims to examine and compare psychologies (and hence psychiatries) derived from modern western philosophy, with similar concepts in other cultures, through the study of developments in terminology, in terms of the simplest facts about what it means to be human. Terminology used in mental health in western cultures is examined, with particular consideration of the term "self" as it has come to be used in a technical sense. Analogous terms from non-English speaking European languages, and some non-western cultures are studied. Western philosophy and psychology have evolved a meaning for the term "self" which is quite different from equivalent terms in non-western cultures. It is a moot point whether or not the development in western psychiatry of what are now technical terms to describe normal human experience has become needlessly obscure and ambiguous. It is not evident that this "new" language represents a genuine advance in understanding; it distances mental health professionals from those who are not familiar with it; and it makes transcultural dialogue difficult.

  5. Advanced electron microscopy characterization of nanomaterials for catalysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Su, Dong

    Transmission electron microscopy (TEM) has become one of the most powerful techniques in the fields of material science, inorganic chemistry and nanotechnology. In terms of resolutions, advanced TEM may reach a high spatial resolution of 0.05 nm, a high energy-resolution of 7 meV. In addition, in situ TEM can help researcher to image the process happened within 1 ms. This paper reviews the recent technical approaches of applying advanced TEM characterization on nanomaterials for catalysis. The text is organized according to the demanded information of nanocrystals from the perspective of application: for example, size, composition, phase, strain, and morphology. Themore » electron beam induced effect and in situ TEM are also introduced. As a result, I hope this review can help the scientists in related fields to take advantage of advanced TEM to their own researches.« less

  6. Advanced electron microscopy characterization of nanomaterials for catalysis

    DOE PAGES

    Su, Dong

    2017-04-01

    Transmission electron microscopy (TEM) has become one of the most powerful techniques in the fields of material science, inorganic chemistry and nanotechnology. In terms of resolutions, advanced TEM may reach a high spatial resolution of 0.05 nm, a high energy-resolution of 7 meV. In addition, in situ TEM can help researcher to image the process happened within 1 ms. This paper reviews the recent technical approaches of applying advanced TEM characterization on nanomaterials for catalysis. The text is organized according to the demanded information of nanocrystals from the perspective of application: for example, size, composition, phase, strain, and morphology. Themore » electron beam induced effect and in situ TEM are also introduced. As a result, I hope this review can help the scientists in related fields to take advantage of advanced TEM to their own researches.« less

  7. Relationship between intraoperative non-technical performance and technical events in bariatric surgery.

    PubMed

    Fecso, A B; Kuzulugil, S S; Babaoglu, C; Bener, A B; Grantcharov, T P

    2018-03-30

    The operating theatre is a unique environment with complex team interactions, where technical and non-technical performance affect patient outcomes. The correlation between technical and non-technical performance, however, remains underinvestigated. The purpose of this study was to explore these interactions in the operating theatre. A prospective single-centre observational study was conducted at a tertiary academic medical centre. One surgeon and three fellows participated as main operators. All patients who underwent a laparoscopic Roux-en-Y gastric bypass and had the procedures captured using the Operating Room Black Box ® platform were included. Technical assessment was performed using the Objective Structured Assessment of Technical Skills and Generic Error Rating Tool instruments. For non-technical assessment, the Non-Technical Skills for Surgeons (NOTSS) and Scrub Practitioners' List of Intraoperative Non-Technical Skills (SPLINTS) tools were used. Spearman rank-order correlation and N-gram statistics were conducted. Fifty-six patients were included in the study and 90 procedural steps (gastrojejunostomy and jejunojejunostomy) were analysed. There was a moderate to strong correlation between technical adverse events (r s  = 0·417-0·687), rectifications (r s  = 0·380-0·768) and non-technical performance of the surgical and nursing teams (NOTSS and SPLINTS). N-gram statistics showed that after technical errors, events and prior rectifications, the staff surgeon and the scrub nurse exhibited the most positive non-technical behaviours, irrespective of operator (staff surgeon or fellow). This study demonstrated that technical and non-technical performances are related, on both an individual and a team level. Valuable data can be obtained around intraoperative errors, events and rectifications. © 2018 BJS Society Ltd Published by John Wiley & Sons Ltd.

  8. MO-FG-207-01: Technological Advances and Challenges: Experience with the First Integrated Whole-Body PET/MRI

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Laforest, R.

    2015-06-15

    The use of integrated PET/MRI systems in clinical applications can best benefit from understanding their technological advances and limitations. The currently available clinical PET/MRI systems have their own characteristics. Thorough analyses of existing technical data and evaluation of necessary performance metrics for quality assurances could be conducted to optimize application-specific PET/MRI protocols. This Symposium will focus on technical advances and limitations of clinical PET/MRI systems, and how this exciting imaging modality can be utilized in applications that can benefit from both PET and MRI. Learning Objectives: To understand the technological advances of clinical PET/MRI systems To correctly identify clinical applicationsmore » that can benefit from PET/MRI To understand ongoing work to further improve the current PET/MRI technology Floris Jansen is a GE Healthcare employee.« less

  9. Advanced technology gas-fired commercial clothes dryer. Final report, April 1985-December 1988

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Topping, R.F.

    1991-04-01

    The objective of this effort was to demonstrate the technical feasibility of an advanced technology commercial clothes dryer (ATD) which could provide improved fuel efficiency and reduced drying time without burning or otherwise damaging the clothes load.

  10. Advanced technical skills are required for microsurgical clipping of posterior communicating artery aneurysms in the endovascular era.

    PubMed

    Sanai, Nader; Caldwell, Nolan; Englot, Dario J; Lawton, Michael T

    2012-08-01

    Many neurosurgeons feel competent clipping posterior communicating artery (PCoA) aneurysms and include this lesion in their practice. However, endovascular therapy removes simple aneurysms that would have been easiest to clip with the best results. What remains are aneurysms with complex anatomy and technical challenges that are not well described. A contemporary surgical series with PCoA aneurysms is reviewed to define the patients, microsurgical techniques, and outcomes in current practice. A total of 218 patients had 218 PCoA aneurysms that were treated microsurgically during an 11-year period. Complexities influencing aneurysm management included (1) large/giant size; (2) fetal posterior cerebral artery; (3) previous coiling; (4) anterior clinoidectomy; (5) adherence of the anterior choroidal artery (AChA); (6) intraoperative aneurysm rupture; (7) complex clipping; and (8) atherosclerotic calcification. Simple PCoA aneurysms were encountered in 113 patients (51.8%) and complex aneurysms in 105 (48.2%). Adherent AChA (13.8%) and intraoperative rupture (11.5%) were the most common complexities. Simple aneurysms had favorable outcomes in 86.6% of patients, whereas aneurysms with 1 or multiple complexities had favorable outcomes in 78.2% and 75.0%, respectively. Intraoperative rupture (P < .01), large/giant size (P = .04), and complex clipping (P = .05) were associated with increased neurological worsening. Because endovascular therapy alters the surgical population, neurosurgeons should recalibrate their expectations with this once straightforward aneurysm. The current mix of PCoA aneurysms requires advanced techniques including clinoidectomy, AChA microdissection, complex clipping, and facility with intraoperative rupture. Microsurgery is recommended for recurrent aneurysms after coiling, complex branches, aneurysms causing oculomotor nerve palsy, multiple aneurysms, and patients with hematomas.

  11. Advanced Rechargeable Lithium Sulfur Dioxide Cell

    DTIC Science & Technology

    1991-11-01

    AD-A274 908IIIIlIIIE McDonald , P. Harris, F. Goebel, S. Hossi ierra, M. Guentert, C. Todino 7 ad r nse TECHNICAL PRODUCTS INCY DTIC ELECTE JAN26 1994...Pawcatuck, CT 06379 94-02298 1425 Best Available Copy I ADVANCED RECHARGEABLE LITHIUM SULFUR DIOXIDE CELL I R.C. McDonald , P. Harris, F. Goebel, S. Hossain...20 minutes. The electrochemical measurements were carried out using a I Starbuck 20-station cycler system which is connected to a computer to monitor

  12. Advanced in-duct sorbent injection for SO{sub 2} control. Final technical report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stouffer, M.R.; Withium, J.A.; Rosenhoover, W.A.

    1994-12-01

    The objective of this research project was to develop a second generation duct sorbent injection technology as a cost-effective compliance option for the 1990 Clean Air Act Amendments. Research and development work was focused on the Advanced Coolside process, which showed the potential for exceeding the original performance targets of 90% SO{sub 2} removal and 60% sorbent utilization. Process development was conducted in a 1000 acfm pilot plant. The pilot plant testing showed that the Advanced Coolside process can achieve 90% SO{sub 2} removal at sorbent utilizations up to 75%. The testing also showed that the process has the potentialmore » to achieve very high removal efficiency (90 to >99%). By conducting conceptual process design and economic evaluations periodically during the project, development work was focused on process design improvements which substantially lowered process capital and operating costs, A final process economic study projects capital costs less than one half of those for limestone forced oxidation wet FGD. Projected total SO{sub 2} control cost is about 25% lower than wet FGD for a 260 MWe plant burning a 2.5% sulfur coal. A waste management study showed the acceptability of landfill disposal; it also identified a potential avenue for by-product utilization which should be further investigated. Based on the pilot plant performance and on the above economic projections, future work to scale up the Advanced Coolside process is recommended.« less

  13. [Technical advancements in cochlear implants : State of the art].

    PubMed

    Büchner, A; Gärtner, L

    2017-04-01

    Twenty years ago, cochlear implants (CI) were indicated only in cases of profound hearing loss or complete deafness. While from today's perspective the technology was clumsy and provided patients with only limited speech comprehension in quiet scenarios, successive advances in CI technology and the consequent substantial hearing improvements over time have since then resulted in continuous relaxation of indication criteria toward residual hearing. While achievements in implant and processor electronics have been one key factor for the ever-improving hearing performance, development of electro-acoustic CI systems-together with atraumatic implantation concepts-has led to enormous improvements in patients with low-frequency residual hearing. Manufactures have designed special processors with integrated hearing aid components for this patient group, which are capable of conveying acoustic and electric stimulation. A further milestone in improvement of hearing in challenging listening environments was the adoption of signal enhancement algorithms and assistive listening devices from the hearing aid industry. This article gives an overview of the current state of the art in the abovementioned areas of CI technology.

  14. Advanced Stirling Convertor (ASC) Development for NASA RPS

    NASA Technical Reports Server (NTRS)

    Wong, Wayne A.; Wilson, Scott; Collins, Josh

    2014-01-01

    Sunpower's Advanced Stirling Convertor (ASC) initiated development under contract to the NASA Glenn Research Center (GRC) and after a series of successful demonstrations, the ASC began transitioning from a technology development project to flight development project. The ASC has very high power conversion efficiency making it attractive for future Radioisotope Power Systems (RPS) in order to make best use of the low plutonium-238 fuel inventory in the U.S. In recent years, the ASC became part of the NASA-Department of Energy Advanced Stirling Radioisotope Generator (ASRG) Integrated Project. Sunpower held two parallel contracts to produce ASC convertors, one with the Department of Energy/Lockheed Martin to produce the ASC-F flight convertors, and one with NASA GRC for the production of ASC-E3 engineering units, the initial units of which served as production pathfinders. The integrated ASC technical team successfully overcame various technical challenges that led to the completion and delivery of the first two pairs of flight-like ASC-E3 by 2013. However, in late Fall 2013, the DOE initiated termination of the Lockheed Martin ASRG flight development contract driven primarily by budget constraints. NASA continues to recognize the importance of high efficiency ASC power conversion for RPS and continues investment in the technology including the continuation of ASC-E3 production at Sunpower and the assembly of the ASRG Engineering Unit #2. This paper provides a summary of ASC technical accomplishments, overview of tests at GRC, plans for continued ASC production at Sunpower, and status of Stirling technology development.

  15. Advancing the practice of systems engineering at JPL

    NASA Technical Reports Server (NTRS)

    Jansma, Patti A.; Jones, Ross M.

    2006-01-01

    In FY 2004, JPL launched an initiative to improve the way it practices systems engineering. The Lab's senior management formed the Systems Engineering Advancement (SEA) Project in order to "significantly advance the practice and organizational capabilities of systems engineering at JPL on flight projects and ground support tasks." The scope of the SEA Project includes the systems engineering work performed in all three dimensions of a program, project, or task: 1. the full life-cycle, i.e., concept through end of operations 2. the full depth, i.e., Program, Project, System, Subsystem, Element (SE Levels 1 to 5) 3. the full technical scope, e.g., the flight, ground and launch systems, avionics, power, propulsion, telecommunications, thermal, etc. The initial focus of their efforts defined the following basic systems engineering functions at JPL: systems architecture, requirements management, interface definition, technical resource management, system design and analysis, system verification and validation, risk management, technical peer reviews, design process management and systems engineering task management, They also developed a list of highly valued personal behaviors of systems engineers, and are working to inculcate those behaviors into members of their systems engineering community. The SEA Project is developing products, services, and training to support managers and practitioners throughout the entire system lifecycle. As these are developed, each one needs to be systematically deployed. Hence, the SEA Project developed a deployment process that includes four aspects: infrastructure and operations, communication and outreach, education and training, and consulting support. In addition, the SEA Project has taken a proactive approach to organizational change management and customer relationship management - both concepts and approaches not usually invoked in an engineering environment. This paper'3 describes JPL's approach to advancing the practice of

  16. Medical Laboratory Technician--Microbiology, 10-3. Military Curriculum Materials for Vocational and Technical Education.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. National Center for Research in Vocational Education.

    This course, the second of three courses in the medical laboratory technician field adapted from military curriculum materials for use in vocational and technical education, was designed as a refresher course for student self-study and evaluation. It is suitable for use by advanced students or beginning students participating in a supervised…

  17. Technical note: Efficient online source identification algorithm for integration within a contamination event management system

    NASA Astrophysics Data System (ADS)

    Deuerlein, Jochen; Meyer-Harries, Lea; Guth, Nicolai

    2017-07-01

    Drinking water distribution networks are part of critical infrastructures and are exposed to a number of different risks. One of them is the risk of unintended or deliberate contamination of the drinking water within the pipe network. Over the past decade research has focused on the development of new sensors that are able to detect malicious substances in the network and early warning systems for contamination. In addition to the optimal placement of sensors, the automatic identification of the source of a contamination is an important component of an early warning and event management system for security enhancement of water supply networks. Many publications deal with the algorithmic development; however, only little information exists about the integration within a comprehensive real-time event detection and management system. In the following the analytical solution and the software implementation of a real-time source identification module and its integration within a web-based event management system are described. The development was part of the SAFEWATER project, which was funded under FP 7 of the European Commission.

  18. Advanced extravehicular activity systems requirements definition study. Phase 2: Extravehicular activity at a lunar base

    NASA Technical Reports Server (NTRS)

    Neal, Valerie; Shields, Nicholas, Jr.; Carr, Gerald P.; Pogue, William; Schmitt, Harrison H.; Schulze, Arthur E.

    1988-01-01

    The focus is on Extravehicular Activity (EVA) systems requirements definition for an advanced space mission: remote-from-main base EVA on the Moon. The lunar environment, biomedical considerations, appropriate hardware design criteria, hardware and interface requirements, and key technical issues for advanced lunar EVA were examined. Six remote EVA scenarios (three nominal operations and three contingency situations) were developed in considerable detail.

  19. Greening the Grid - Advancing Solar, Wind, and Smart Grid Technologies (Spanish Version)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    This is the Spanish version of 'Greening the Grid - Advancing Solar, Wind, and Smart Grid Technologies'. Greening the Grid provides technical assistance to energy system planners, regulators, and grid operators to overcome challenges associated with integrating variable renewable energy into the grid.

  20. Personal Identification of Deceased Persons: An Overview of the Current Methods Based on Physical Appearance.

    PubMed

    Caplova, Zuzana; Obertova, Zuzana; Gibelli, Daniele M; De Angelis, Danilo; Mazzarelli, Debora; Sforza, Chiarella; Cattaneo, Cristina

    2018-05-01

    The use of the physical appearance of the deceased has become more important because the available antemortem information for comparisons may consist only of a physical description and photographs. Twenty-one articles dealing with the identification based on the physiognomic features of the human body were selected for review and were divided into four sections: (i) visual recognition, (ii) specific facial/body areas, (iii) biometrics, and (iv) dental superimposition. While opinions about the reliability of the visual recognition differ, the search showed that it has been used in mass disasters, even without testing its objectivity and reliability. Specific facial areas being explored for the identification of dead; however, their practical use is questioned, similarly to soft biometrics. The emerging dental superimposition seems to be the only standardized and successfully applied method for identification so far. More research is needed into a potential use of the individualizing features, considering that postmortem changes and technical difficulties may affect the identification. © 2017 American Academy of Forensic Sciences.