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1

Emulsion Chamber Technology Experiment (ECT)  

NASA Technical Reports Server (NTRS)

The experimental objective of Emulsion Chamber Technology (ECT) was to develop space-borne emulsion chamber technology so that cosmic rays and nuclear interactions may subsequently be studied at extremely high energies with long exposures in space. A small emulsion chamber was built and flown on flight STS-62 of the Columbia in March 1994. Analysis of the several hundred layers of radiation-sensitive material has shown excellent post-flight condition and suitability for cosmic ray physics analysis at much longer exposures. Temperature control of the stack was 20 +/-1 C throughout the active control period and no significant deviations of temperature or pressure in the chamber were observed over the entire mission operations period. The unfortunate flight attitude of the orbiter (almost 90% Earth viewing) prevented any significant number of heavy particles (Z greater than or equal to 10) reaching the stack and the inverted flow of shower particles in the calorimeter has not allowed evaluation of absolute primary cosmic ray-detection efficiency nor of the practical time limits of useful exposure of these calorimeters in space to the level of detail originally planned. Nevertheless, analysis of the observed backgrounds and quality of the processed photographic and plastic materials after the flight show that productive exposures of emulsion chambers are feasible in low orbit for periods of up to one year or longer. The engineering approaches taken in the ECT program were proven effective and no major environmental obstacles to prolonged flight are evident.

Gregory, John C.; Takahashi, Yoshiyuki

1996-01-01

2

Emerging Communication Technologies (ECT) Phase 4 Report  

NASA Technical Reports Server (NTRS)

The Emerging Communication Technology (ECT) project investigated three First Mile communication technologies in support of NASA s Crew Exploration Vehicle (CEV), Advanced Range Technology Working Group (ARTWG), and the Advanced Spaceport Technology Working Group (ASTWG). These First Mile technologies have the purpose of interconnecting mobile users with existing Range Communication infrastructures on a 24/7 basis. ECT is a continuation of the Range Information System Management (RISM) task started in 2002. This is the fourth year of the project.

Bastin, Gary L.; Harris, William G.; Marin, Jose A.; Nelson, Richard A.

2005-01-01

3

Emerging Communication Technologies (ECT) Phase 3 Final Report  

NASA Technical Reports Server (NTRS)

The Emerging Communication Technology (ECT) project investigated three First Mile communication technologies in support of NASA s Second Generation Reusable Launch Vehicle (2nd Gen RLV), Orbital Space Plane, Advanced Range Technology Working Group (ARTWG) and the Advanced Spaceport Technology Working Group (ASTWG). These First Mile technologies have the purpose of interconnecting mobile users with existing Range Communication infrastructures. ECT was a continuation of the Range Information System Management (RISM) task started in 2002. RISM identified the three advance communication technologies investigated under ECT. These were Wireless Ethernet (Wi-Fi), Free Space Optics (FSO), and Ultra Wideband (UWB). Due to the report s size, it has been broken into three volumes: 1) Main Report 2) Appendices 3) UWB.

Bastin, Gary L.; Harris, William G.; Bates, Lakesha D.; Nelson, Richard A.

2004-01-01

4

Emerging Communication Technologies (ECT) Phase 2 Report. Volume 2; Appendices  

NASA Technical Reports Server (NTRS)

The Emerging Communication Technology (ECT) project investigated three First Mile communication technologies in support of NASA s Second Generation Reusable Launch Vehicle (2nd Gen RLV), Orbital Space Plane, Advanced Range Technology Working Group (ARTWG) and the Advanced Spaceport Technology Working Group (ASTWG). These First Mile technologies have the purpose of interconnecting mobile users with existing Range Communication infrastructures. ECT was a continuation of the Range Information System Management (RISM) task started in 2002. RISM identified the three advance communication technologies investigated under ECT. These were Wireless Ethernet (Wi-Fi), Free Space Optics (FSO), and Ultra Wideband (UWB). Due to the report s size, it has been broken into three volumes: 1) Main Report 2) Appendices 3) UWB

Bastin, Gary L.; Harris, William G.; Chiodini, Robert; Nelson, Richard A.; Huang, PoTien; Kruhm, David A.

2003-01-01

5

Emerging Communication Technologies (ECT) Phase 2 Report. Volume 1; Main Report  

NASA Technical Reports Server (NTRS)

The Emerging Communication Technology (ECT) project investigated three First Mile communication technologies in support of NASA s Second Generation Reusable Launch Vehicle (2nd Gen RLV), Orbital Space Plane, Advanced Range Technology Working Group (ARTWG) and the Advanced Spaceport Technology Working Group (ASTWG). These First Mile technologies have the purpose of interconnecting mobile users with existing Range Communication infrastructures. ECT was a continuation of the Range Information System Management (RISM) task started in 2002. RISM identified the three advance communication technologies investigated under ECT. These were Wireless Ethernet (Wi-Fi), Free Space Optics (FSO), and Ultra Wideband (UWB). Due to the report s size, it has been broken into three volumes: 1) Main Report 2) Appendices 3) UWB.

Bastin, Gary L.; Harris, William G.; Chiodini, Robert; Nelson, Richard A.; Huang, PoTien; Kruhm, David A.

2003-01-01

6

Advances in lens implant technology  

PubMed Central

Cataract surgery is one of the oldest and the most frequent outpatient clinic operations in medicine performed worldwide. The clouded human crystalline lens is replaced by an artificial intraocular lens implanted into the capsular bag. During the last six decades, cataract surgery has undergone rapid development from a traumatic, manual surgical procedure with implantation of a simple lens to a minimally invasive intervention increasingly assisted by high technology and a broad variety of implants customized for each patient’s individual requirements. This review discusses the major advances in this field and focuses on the main challenge remaining – the treatment of presbyopia. The demand for correction of presbyopia is increasing, reflecting the global growth of the ageing population. Pearls and pitfalls of currently applied methods to correct presbyopia and different approaches under investigation, both in lens implant technology and in surgical technology, are discussed. PMID:23413369

Kampik, Anselm; Dexl, Alois K.; Zimmermann, Nicole; Glasser, Adrian; Baumeister, Martin; Kohnen, Thomas

2013-01-01

7

Microsystem technologies for ophtalmological implants  

NASA Astrophysics Data System (ADS)

Due to the low power consumption CMOS electronics is ideal for the use in implanted systems. This paper presents two projects working on ophthalmological implants. Both systems are powered by an external RF-field. One system has been developed to measure the intraocular pressure continuously which is important for the therapy of glaucoma patients. The system consists of a micro coil and an integrated pressure transponder chip built into an artificial soft lens. A second example is a very complex system for epiretinal stimulation of the nerve cells of the retina. With such a system it might be possible to give blind people that are suffering from retinitis pigmentosa some visual contact to their surrounding.

Mokwa, Wilfried

2003-01-01

8

Implanted : technology and connection in the deaf world  

E-print Network

In 1984, the FDA approved a medical device called a cochlear implant for adult use in the United States. Unlike assistive hearing technologies that came before it, such as hearing aids, cochlear implants could offer wider ...

Calamia, Joseph Benjamin

2010-01-01

9

WHAT IS ECT? DOES ECT WORK?  

E-print Network

in patients with severe major depression or bipolar disorder that has not responded to other treatments-term relief of major depressive disorder and other severe mental illnesses, such as bipolar disorder with the consequences of ineffectively treated severe psychiatric disorders. For some patients, the risks of ECT may

Oliver, Douglas L.

10

Study on application of aerospace technology to improve surgical implants  

NASA Technical Reports Server (NTRS)

The areas where aerospace technology could be used to improve the reliability and performance of metallic, orthopedic implants was assessed. Specifically, comparisons were made of material controls, design approaches, analytical methods and inspection approaches being used in the implant industry with hardware for the aerospace industries. Several areas for possible improvement were noted such as increased use of finite element stress analysis and fracture control programs on devices where the needs exist for maximum reliability and high structural performance.

Johnson, R. E.; Youngblood, J. L.

1982-01-01

11

Amplification, Technology, and Cochlear Implants for Infants.  

ERIC Educational Resources Information Center

Early amplification is crucial to efficient habilitation and development of oral communication skills in hearing-impaired infants. Initial evaluation and fitting of amplification is a joint effort by the audiologist, therapist, and parents, whether the child uses traditional hearing aids or cochlear implants, and should be supplemented by a…

Adam, Arlie J.

1993-01-01

12

Evaluating the Feasibility of Using Remote Technology for Cochlear Implants  

PubMed Central

The use of remote technology to provide cochlear implant services has gained popularity in recent years. This article contains a review of research evaluating the feasibility of remote service delivery for recipients of cochlear implants. To date, published studies have determined that speech-processor programming levels and other objective tests (electrode impedance and electrically evoked compound action potentials) are equivalent to those obtained in the face-to-face condition. Despite these promising findings, speech perception using remote technology has proven to be more challenging. Previous investigations have evaluated speech perception with recipients of cochlear implants using videoconference (Polycom) equipment in nonsound-treated rooms (due to lack of access to audiological sound booths in rural areas). Results have revealed poorer speech perception scores using remote technology compared to face-to-face results. Additionally, it has been shown that Polycom transmission of a speech stimulus does not cause significant compression for adequate evaluation; rather, poorer results are due to testing performed in nonsound-treated environments. Based on the literature, telepractice is a feasible option for cochlear implant service delivery. Barriers to the wide-spread use of remote services for recipients of cochlear implants include a uniform system for the evaluation of speech perception, validation of services for pediatric recipients and initial activations, license reciprocity, and reimbursement for services.

Goehring, Jenny L.; Hughes, Michelle L.; Baudhuin, Jacquelyn L.

2012-01-01

13

Adverse psychological effects of ECT  

Microsoft Academic Search

Although it is known that a proportion of people find ECT distressing to receive, these adverse psychological reactions are little understood. Twenty people who reported having found ECT upsetting were interviewed about their experiences in detail. A variety of them es emerged, including feelings of fear, shame and hum iliation, worthlessness and helplessness, and a sense of having been abused

LUCY JOHNSTONE

1999-01-01

14

Adaptation of NASA technology for the optimum design of orthopedic knee implants.  

PubMed

NASA technology originally developed for designing aircraft turbine-engine blades has been adapted and applied to orthopedic knee implants. This article describes a method for tailoring an implant for optimal interaction with the environment of the tibia. The implant components are designed to control stresses in the bone for minimizing bone degradation and preventing failures. Engineers expect the tailoring system to improve knee prosthesis design and allow customized implants for individual patients. PMID:10150099

Saravanos, D A; Mraz, P J; Davy, D T; Hopkins, D A

1991-03-01

15

Science and technology of biocompatible thin films for implantable biomedical devices.  

SciTech Connect

This presentation focuses on reviewing research to develop two critical biocompatible film technologies to enable implantable biomedical devices, namely: (1) development of bioinert/biocompatible coatings for encapsulation of Si chips implantable in the human body (e.g., retinal prosthesis implantable in the human eye) - the coating involves a novel ultrananocrystalline diamond (UNCD) film or hybrid biocompatible oxide/UNCD layered films; and (2) development of biocompatible films with high-dielectric constant and microfabrication process to produce energy storage super-capacitors embedded in the microchip to achieve full miniaturization for implantation into the human body.

Li, W.; Kabius, B.; Auciello, O.; Materials Science Division

2010-01-01

16

Adaptation of NASA technology for the optimization of orthopedic knee implants  

NASA Technical Reports Server (NTRS)

The NASA technology originally developed for the optimization of composite structures (engine blades) is adapted and applied to the optimization of orthopedic knee implants. A method is developed enabling the tailoring of the implant for optimal interaction with the environment of the tibia. The shape of the implant components are optimized, such that the stresses in the bone are favorably controlled to minimize bone degradation and prevent failures. A pilot tailoring system is developed and the feasibility of the concept is elevated. The optimization system is expected to provide the means for improving knee prosthesis and individual implant tailoring for each patient.

Saravanos, D. A.; Mraz, P. J.; Hopkins, D. A.

1991-01-01

17

Technological, biological, and acoustical constraints to music perception in cochlear implant users.  

PubMed

Despite advances in technology, the ability to perceive music remains limited for many cochlear implant users. This paper reviews the technological, biological, and acoustical constraints that make music an especially challenging stimulus for cochlear implant users, while highlighting recent research efforts to overcome these shortcomings. The limitations of cochlear implant devices, which have been optimized for speech comprehension, become evident when applied to music, particularly with regards to inadequate spectral, fine-temporal, and dynamic range representation. Beyond the impoverished information transmitted by the device itself, both peripheral and central auditory nervous system deficits are seen in the presence of sensorineural hearing loss, such as auditory nerve degeneration and abnormal auditory cortex activation. These technological and biological constraints to effective music perception are further compounded by the complexity of the acoustical features of music itself that require the perceptual integration of varying rhythmic, melodic, harmonic, and timbral elements of sound. Cochlear implant users not only have difficulty perceiving spectral components individually (leading to fundamental disruptions in perception of pitch, melody, and harmony) but also display deficits with higher perceptual integration tasks required for music perception, such as auditory stream segregation. Despite these current limitations, focused musical training programs, new assessment methods, and improvements in the representation and transmission of the complex acoustical features of music through technological innovation offer the potential for significant advancements in cochlear implant-mediated music perception. PMID:23665130

Limb, Charles J; Roy, Alexis T

2014-02-01

18

The role of ECT in suicide prevention.  

PubMed

Suicide is a leading cause of death among psychiatric patients, and a leading cause of death from all causes in people younger than 30 years. The rapid relief of severe depression, mania, and psychosis by electroconvulsive therapy (ECT) is accompanied by the rapid reduction in suicide drive. Electroconvulsive therapy use is, however, inhibited by fear of electricity, unreasoned prejudice, legislative restrictions, and the limited availability of trained professionals and adequate facilities. This review assesses the experience with ECT in persons with suicide risk and recommends the consideration of ECT in treatment algorithms to reduce suicide rates. PMID:24091903

Fink, Max; Kellner, Charles H; McCall, W Vaughn

2014-03-01

19

Evolution and acceptability of medical applications of RFID implants among early users of technology.  

PubMed

RFID as a wireless identification technology that may be combined with microchip implants have tremendous potential in today's market. Although these implants have their advantages and disadvantages, recent improvements how allowed for implants designed for humans. Focus was given to the use of RFID tags and its effects on technology and CRM through a case study on VeriChip, the only corporation to hold the rights and the patent to the implantable chip for humans, and an empirically based study on working professionals to measure perceptions by early adopters of such technology. Through hypotheses-testing procedures, it was found that although some resistance to accept microchip implants was found in several applications, especially among gender, it was totally expected that healthcare and medical record keeping activities would be universally treated in a positive light and the use of authorities (namely governmental agencies) would be equally treated in a negative light by both sexes. Future trends and recommendations are presented along with statistical results collected through personal interviews. PMID:19042524

Smith, Alan D

2007-01-01

20

Plasma-based ion implantation : a valuable technology for the elaboration of innovative materials and nanostructured thin films  

E-print Network

Plasma-based ion implantation : a valuable technology for the elaboration of innovative materials, France Abstract. Plasma-based ion implantation (PBII), invented in 1987, can now be considered as a mature technology for thin film modification. After a short recall of the principle and physics of PBII

Paris-Sud XI, Université de

21

Contacting the brain--aspects of a technology assessment of neural implants.  

PubMed

The public interest in neural implants has grown considerably in recent years. Progress within related research areas in combination with increasing--albeit overly optimistic and indiscriminate--mass media coverage have led to the impression that the possibilities of neural prosthetics have grown enormously. But a closer look reveals that the reasons for the intensified interest are varied and cannot be attributed to technical progress alone. Some neural prostheses that have been under development for many years have not left the clinical development phase despite intensive research activities. Other implants, like cardiac pacemakers and cochlea implants, are mature products that have already been implanted in a large number of patients. From the public perspective and in media reports, progress in the development of neural implants is associated with new achievements in other fields of neuroscience. Communications on new applications of functional magnetic resonance imaging (fMRI) may suggest that a number of cognitive functions are now easily accessible with technological means. The fact that the interpretation of the results of fMRI studies depends on many conditions and is partly disputed also within the scientific community has been discussed in many publications but only very limited, in the general media. Besides this, research results and implementations in the area of electroencephalography and magnetoencephalography have sparked further debate on the question of free will, on determinism and indeterminism, and have attracted a large media response. The purpose of this paper is to discuss some societal and ethical aspects of neural implants from a technology assessment perspective. Technology assessment (TA) aims at providing knowledge about impacts and consequences of (new) technologies as well as about political and societal ways of dealing with them. It reflects about implementation conditions of technology and potential technology conflicts. Over the last years, neural implants became a subject for TA since they have gained a higher attention in both the political arena and the general public. Especially the ethical and social implications of technologies that electrically stimulate the brain and the possibilities of changing personality traits, changing moods, and perhaps enhancing human cognitive capabilities are central issues in related discussions. In this paper, we want to briefly summarize some of the key arguments as well as topics for future discussion and research. PMID:19072906

Decker, Michael; Fleischer, Torsten

2008-12-01

22

A 50 GHz implanted base silicon bipolar technology with 35 GHz static frequency divider  

Microsoft Academic Search

A 0.5 ?m silicon bipolar technology for mixed digital\\/analogue RF applications is presented. Very steep base profiles are realized by ion implantation and subsequent base diffusion. Cut-off frequencies and maximum oscillation frequencies of 50 GHz and ECL gate delay of 16 ps are obtained without increasing the process complexity in comparison to a 0.8 ?m production technology. A static 2:1

J. Bok; A. Felder; T. F. Meister; M. Franosch; K. Aufinger; M. Wurzer; R. Schreiter; S. Boguth; L. Treitinger

1996-01-01

23

Implantable sensor technology: measuring bone and joint biomechanics of daily life in vivo  

PubMed Central

Stresses and strains are major factors influencing growth, remodeling and repair of musculoskeletal tissues. Therefore, knowledge of forces and deformation within bones and joints is critical to gain insight into the complex behavior of these tissues during development, aging, and response to injury and disease. Sensors have been used in vivo to measure strains in bone, intraarticular cartilage contact pressures, and forces in the spine, shoulder, hip, and knee. Implantable sensors have a high impact on several clinical applications, including fracture fixation, spine fixation, and joint arthroplasty. This review summarizes the developments in strain-measurement-based implantable sensor technology for musculoskeletal research. PMID:23369655

2013-01-01

24

Full chip implant correction with wafer topography OPC modeling in 2x nm bulk technologies  

NASA Astrophysics Data System (ADS)

Ionic implantation photolithography step considered to be non critical started to be influenced by unwanted overexposure by wafer topography with technology node downscaling evolution [1], [2]. Starting from 2xnm technology nodes, implant patterns modulated on wafer by classical implant proximity effects are also influenced by wafer topography which can cause drastic pattern degradation [2], [3]. This phenomenon is expected to be attenuated by the use of anti-reflecting coating but it increases process complexity and involves cost and cycle time penalty. As a consequence, computational lithography solutions are currently under development in order to correct wafer topographical effects on mask [3]. For ionic implantation source Drain (SD) on Silicon bulk substrate, wafer topography effects are the consequence of active silicon substrate, poly patterns, STI stack, and transitions between patterned wafer stack. In this paper, wafer topography aware OPC modeling flow taking into account stack effects for bulk technology is presented. Quality check of this full chip stack aware OPC model is shown through comparison of mask computational verification and known systematic defectivity on wafer. Also, the integration of topographical OPC model into OPC flow for chip scale mask correction is presented with quality and run time penalty analysis.

Michel, J.-C.; Le Denmat, J.-C.; Sungauer, E.; Robert, F.; Yesilada, E.; Armeanu, A.-M.; Entradas, J.; Sturtevant, J. L.; Do, T.; Granik, Y.

2013-09-01

25

SEMICONDUCTOR DEVICES: Reducing the influence of STI on SONOS memory through optimizing added boron implantation technology  

NASA Astrophysics Data System (ADS)

The influence of shallow trench isolation (STI) on a 90 nm polysilicon-oxide-nitride-oxide-silicon structure non-volatile memory has been studied based on experiments. It has been found that the performance of edge memory cells adjacent to STI deteriorates remarkably. The compressive stress and boron segregation induced by STI are thought to be the main causes of this problem. In order to mitigate the STI impact, an added boron implantation in the STI region is developed as a new solution. Four kinds of boron implantation experiments have been implemented to evaluate the impact of STI on edge cells, respectively. The experimental results show that the performance of edge cells can be greatly improved through optimizing added boron implantation technology.

Yue, Xu; Feng, Yan; Zhiguo, Li; Fan, Yang; Yonggang, Wang; Jianguang, Chang

2010-09-01

26

Status of p-on- n Arsenic-Implanted HgCdTe Technologies  

NASA Astrophysics Data System (ADS)

In this paper recent developments made by the French Atomic Energies and Alternative Energies Commission (CEA) at the Electronics and Information Technology Laboratory (LETI) on the fabrication of planar p-on- n HgCdTe photodiodes are reported. Results obtained on long-wavelength infrared (LWIR) liquid-phase epitaxy (LPE) and mid- and short-wavelength infrared (MWIR/SWIR) molecular beam epitaxy (MBE) have been previously published. For these photodiodes, p-type doping is obtained by arsenic implantation followed by diffusion and activation under Hg-overpressure annealing. The active layer is n-type doped by indium incorporation during growth. Control of the p-on- n junctions is one of the key points of this technology, requiring good knowledge of the arsenic implantation and diffusion and the evolution of implantation-induced defects. Concerning implantation, the impact of dose (from 2 × 1014 at./cm2 to 2 × 1015 at./cm2) and energy (from 50 keV to 500 keV) on As profiles is considered. The profiles after implantation are modeled using Pearson IV moments. Realistic descriptions of arsenic distributions are obtained, and the evolution of moments with implantation conditions is fitted. In addition, implantation damage is examined by transmission electron microscopy (TEM) and the evolution of defects is studied depending on implantation conditions and Hg-overpressure annealing. Previous results obtained on 30- ?m-pitch LPE LWIR and MBE MWIR/SWIR showed state-of-the-art detector performance. Since these first results, progress has been made to decrease the pixel pitch to 15 ?m and increase the focal-plane array (FPA) format. In this way, 640 × 512 LPE LWIR FPAs have been processed and characterized. In addition we report results obtained on our first p-on- n very long-wavelength infrared (VLWIR) photodiode fabricated at CEA-LETI with ? c = 13.35 ?m at 50 K. These latest results demonstrate the viability of our technology and materials.

Mollard, L.; Destefanis, G.; Bourgeois, G.; Ferron, A.; Baier, N.; Gravrand, O.; Barnes, J. P.; Papon, A. M.; Milesi, F.; Kerlain, A.; Rubaldo, L.

2011-08-01

27

Cryogenic ion implantation near amorphization threshold dose for halo/extension junction improvement in sub-30 nm device technologies  

NASA Astrophysics Data System (ADS)

We report on junction advantages of cryogenic ion implantation with medium current implanters. We propose a methodical approach on maximizing cryogenic effects on junction characteristics near the amorphization threshold doses that are typically used for halo implants for sub-30 nm technologies. BF2+ implant at a dose of 8×1013cm-2 does not amorphize silicon at room temperature. When implanted at -100°C, it forms a 30 - 35 nm thick amorphous layer. The cryogenic BF2+ implant significantly reduces the depth of the boron distribution, both as-implanted and after anneals, which improves short channel rolloff characteristics. It also creates a shallower n+-p junction by steepening profiles of arsenic that is subsequently implanted in the surface region. We demonstrate effects of implant sequences, germanium preamorphization, indium and carbon co-implants for extension/halo process integration. When applied to sequences such as Ge+As+C+In+BF2+, the cryogenic implants at -100°C enable removal of Ge preamorphization, and form more active n+-p junctions and steeper B and In halo profiles than sequences at room temperature.

Park, Hugh; Todorov, Stan; Colombeau, Benjamin; Rodier, Dennis; Kouzminov, Dimitry; Zou, Wei; Guo, Baonian; Khasgiwale, Niranjan; Decker-Lucke, Kurt

2012-11-01

28

Cryogenic ion implantation near amorphization threshold dose for halo/extension junction improvement in sub-30 nm device technologies  

SciTech Connect

We report on junction advantages of cryogenic ion implantation with medium current implanters. We propose a methodical approach on maximizing cryogenic effects on junction characteristics near the amorphization threshold doses that are typically used for halo implants for sub-30 nm technologies. BF{sub 2}{sup +} implant at a dose of 8 Multiplication-Sign 10{sup 13}cm{sup -2} does not amorphize silicon at room temperature. When implanted at -100 Degree-Sign C, it forms a 30 - 35 nm thick amorphous layer. The cryogenic BF{sub 2}{sup +} implant significantly reduces the depth of the boron distribution, both as-implanted and after anneals, which improves short channel rolloff characteristics. It also creates a shallower n{sup +}-p junction by steepening profiles of arsenic that is subsequently implanted in the surface region. We demonstrate effects of implant sequences, germanium preamorphization, indium and carbon co-implants for extension/halo process integration. When applied to sequences such as Ge+As+C+In+BF{sub 2}{sup +}, the cryogenic implants at -100 Degree-Sign C enable removal of Ge preamorphization, and form more active n{sup +}-p junctions and steeper B and In halo profiles than sequences at room temperature.

Park, Hugh; Todorov, Stan; Colombeau, Benjamin; Rodier, Dennis; Kouzminov, Dimitry; Zou Wei; Guo Baonian; Khasgiwale, Niranjan; Decker-Lucke, Kurt [Applied Materials, Varian Semiconductor Equipment, 35 Dory Road, Gloucester, Massachusetts 01930 (United States)

2012-11-06

29

Consent, competency and ECT: some critical suggestions  

PubMed Central

Should the `irrational' refusal to consent to ECT of a depressed patient who knows he is thought to be ill, knows that his doctor believes ECT will help him and knows that he is being asked to decide, be respected or overridden? The author of the first paper, an American bioethicist argues that the refusal should be overridden in the interests of fostering the autonomy of the patient by overcoming the impediment to that autonomy which major depression represents. A philosopher and a psychiatrist respond and an editorial discusses the issues. PMID:6620317

Sherlock, Richard

1983-01-01

30

Complete oral rehabilitation with implants using CAD/CAM technology, stereolithography, and conoscopic holography.  

PubMed

A 64-year-old totally edentulous female initially presented with ill-fitting removable prostheses. A comprehensive treatment plan with dental implants was accepted by the patient. Clinical and laboratory procedures were executed using various computer technologies including computed tomography, rapid prototyping, and optical scanning using conoscopic holography. A review of the patient's treatment and various modalities used are the focus of this patient report. PMID:22223191

Bentz, Robert M; Balshi, Stephen F

2012-02-01

31

Plasma-based ion implantation and deposition: A review of physics,technology, and applications  

SciTech Connect

After pioneering work in the 1980s, plasma-based ion implantation (PBII) and plasma-based ion implantation and deposition (PBIID) can now be considered mature technologies for surface modification and thin film deposition. This review starts by looking at the historical development and recalling the basic ideas of PBII. Advantages and disadvantages are compared to conventional ion beam implantation and physical vapor deposition for PBII and PBIID, respectively, followed by a summary of the physics of sheath dynamics, plasma and pulse specifications, plasma diagnostics, and process modeling. The review moves on to technology considerations for plasma sources and process reactors. PBII surface modification and PBIID coatings are applied in a wide range of situations. They include the by-now traditional tribological applications of reducing wear and corrosion through the formation of hard, tough, smooth, low-friction and chemically inert phases and coatings, e.g. for engine components. PBII has become viable for the formation of shallow junctions and other applications in microelectronics. More recently, the rapidly growing field of biomaterial synthesis makes used of PBII&D to produce surgical implants, bio- and blood-compatible surfaces and coatings, etc. With limitations, also non-conducting materials such as plastic sheets can be treated. The major interest in PBII processing originates from its flexibility in ion energy (from a few eV up to about 100 keV), and the capability to efficiently treat, or deposit on, large areas, and (within limits) to process non-flat, three-dimensional workpieces, including forming and modifying metastable phases and nanostructures. We use the acronym PBII&D when referring to both implantation and deposition, while PBIID implies that deposition is part of the process.

Pelletier, Jacques; Anders, Andre

2005-05-16

32

Could ECT be effective in autism?  

Microsoft Academic Search

Autism is increasingly diagnosed, but therapeutic options are limited in many children. ECT is considered as a safe, effective, and life-saving treatment in people of all ages who suffer from affective disorders, acute psychosis, and, in particular, catatonia. There are recent speculations that certain types of autism may be the earliest expression of catatonia and that both disorders have identical

Dirk M. Dhossche; Sara Stanfill

2004-01-01

33

Side-E ect Removal Transformation Mark Harman, Malcolm Munro,  

E-print Network

in program state that occurs as a by-product of the evaluation of an expres- sion. Side e#11;ects are often a program p which may contain side e#11;ects into a semantically equiva- lent program p 0 which. The Programming Language C Stan- dard de#12;nes side e#11;ects in a more general way: \\Accessing a volatile object

Singer, Jeremy

34

Improvement of P-N Junction Leakage and Reduction in Interface State Density in Transistors by Cryo Implantation Technology  

NASA Astrophysics Data System (ADS)

Cryo implantation by a rapid thermal annealing process was applied to achieve defect-free shallow junctions. Boron ions were implanted in (100) Si substrates cooled using liquid nitrogen, with temperature controlled at -160 °C or lower during ion implantation. It was found that an amorphous layer was formed by boron implantation and that the amorphous layer completely recovered to single crystals after annealing at 900 °C for 30 s. No dislocation was observed in the implanted layer. It was also found that the thermal diffusion of boron was suppressed by cryo implantation. Furthermore, cryo implantation was found to be very effective in reducing the density of defects, and P-N junction leakage was reduced by one order of magnitude compared with that in the case of room temperature implantation. These results suggest that the transient enhanced diffusion of boron can be reduced by suppressing vacancy migration toward the surface during implantation. Moreover, the substrate-cooling effect is very effective for improving surface roughness, and it is a very effective technology not only for reducing Si/SiO2 interface state density but also for improving the reliability of gate oxide.

Murakoshi, Atsushi; Iwase, Masao; Niiyama, Hiromi; Tomita, Mitsuhiro; Suguro, Kyoichi

2013-10-01

35

Repairing an implant titanium milled framework using laser welding technology: a clinical report.  

PubMed

The application of laser welding technology allows titanium to be welded predictably and precisely to achieve accurate fit of a milled framework. Laser energy results in localized heat production, thereby reducing thermal expansion. Unlike soldering, laser energy can be directed to a small area, making it possible to laser weld close to acrylic resin or ceramic. This article describes the use of laser welding to repair an implant titanium milled fixed denture. A quick, cost-effective, accurate repair was accomplished, and the repaired framework possessed adequate strength and the same precise fit as the original framework. PMID:19328274

Prasad, Soni; Monaco, Edward A

2009-04-01

36

Parcours MA (Mathmatiques approfondies) Algbre et Gomtrie (6 ECTS)  

E-print Network

un cours déjà validé. #12;Parcours MI (Mathématiques et Informatique) Semestre 1 Optimisation) Semestre 2 Introduction Programmation C (6 ECTS) Systèmes d'exploitation (4 ECTS) Option Info (2 ECTS Programmation oriente objet, Histoire de Mathématiques, Probabilités 2, Equations Différentielles, Algèbre et

Parusinski, Adam

37

Technology Advances and Challenges in Hermetic Packaging for Implantable Medical Devices  

Microsoft Academic Search

\\u000a Many implantable medical devices contain sophisticated electronic circuits. Hermetic packaging is required to provide the\\u000a implant’s electronic circuitry with protection from the harsh environment of the human body. This chapter provides a review\\u000a of available hermetic sealing methods and their applications. General considerations of implantable medical device packaging\\u000a are discussed. Various testing methods applicable to the packaging of implantable medical

Guangqiang Jiang; David D. Zhou

2010-01-01

38

Bypassing the learning curve in permanent seed implants using state-of-the-art technology  

SciTech Connect

Purpose: The aim of this study was to demonstrate, based on clinical postplan dose distributions, that technology can be used efficiently to eliminate the learning curve associated with permanent seed implant planning and delivery. Methods and Materials: Dose distributions evaluated 30 days after the implant of the initial 22 consecutive patients treated with permanent seed implants at two institutions were studied. Institution 1 (I1) consisted of a new team, whereas institution 2 (I2) had performed more than 740 preplanned implantations over a 9-year period before the study. Both teams had adopted similar integrated systems based on three-dimensional (3D) transrectal ultrasonography, intraoperative dosimetry, and an automated seed delivery and needle retraction system (FIRST, Nucletron). Procedure time and dose volume histogram parameters such as D90, V100, V150, V200, and others were collected in the operating room and at 30 days postplan. Results: The average target coverage from the intraoperative plan (V100) was 99.4% for I1 and 99.9% for I2. D90, V150, and V200 were 191.4 Gy (196.3 Gy), 75.3% (73.0%), and 37.5% (34.1%) for I1 (I2) respectively. None of these parameters shows a significant difference between institutions. The postplan D90 was 151.2 Gy for I1 and 167.3 Gy for I2, well above the 140 Gy from the Stock et al. analysis, taking into account differences at planning, results in a p value of 0.0676. The procedure time required on average 174.4 min for I1 and 89 min for I2. The time was found to decrease with the increasing number of patients. Conclusion: State-of-the-art technology enables a new brachytherapy team to obtain excellent postplan dose distributions, similar to those achieved by an experienced team with proven long-term clinical results. The cost for bypassing the usual dosimetry learning curve is time, with increasing team experience resulting in shorter treatment times.

Beaulieu, Luc [Departement de Radio-oncologie, Centre Hospitalier Universitaire de Quebec, Hotel-Dieu de Quebec, Quebec, PQ (Canada)]. E-mail: beaulieu@phy.ulaval.ca; Evans, Dee-Ann Radford [Departments of Radiation Oncology and Medical Physics, Tom Baker Cancer Centre, Calgary, AB (Canada); Aubin, Sylviane [Departement de Radio-oncologie, Centre Hospitalier Universitaire de Quebec, Hotel-Dieu de Quebec, Quebec, PQ (Canada); Angyalfi, Steven [Departments of Radiation Oncology and Medical Physics, Tom Baker Cancer Centre, Calgary, AB (Canada); Husain, Siraj [Departments of Radiation Oncology and Medical Physics, Tom Baker Cancer Centre, Calgary, AB (Canada); Kay, Ian [Departments of Radiation Oncology and Medical Physics, Tom Baker Cancer Centre, Calgary, AB (Canada); Martin, Andre-Guy [Departement de Radio-oncologie, Centre Hospitalier Universitaire de Quebec, Hotel-Dieu de Quebec, Quebec, PQ (Canada); Varfalvy, Nicolas [Departement de Radio-oncologie, Centre Hospitalier Universitaire de Quebec, Hotel-Dieu de Quebec, Quebec, PQ (Canada); Vigneault, Eric [Departement de Radio-oncologie, Centre Hospitalier Universitaire de Quebec, Hotel-Dieu de Quebec, Quebec, PQ (Canada); Dunscombe, Peter [Departments of Radiation Oncology and Medical Physics, Tom Baker Cancer Centre, Calgary, AB (Canada)

2007-01-01

39

ECT-B-splines defined by generalized divided differences  

NASA Astrophysics Data System (ADS)

ECT-spline curves are generated from different local ECT-systems via connection matrices. If they are nonsingular, lower triangular and totally positive there is a basis of the space of ECT-splines consisting of functions having minimal compact supports, normalized either to form a nonnegative partition of unity or to have integral one. In this paper such ECT-B-splines are defined by generalized divided differences. This definition reduces to the classical one in case of a Schoenberg space. Under suitable assumptions it leads to a recursive method for computing the ECT-B-splines that reduces to the de Boor-Mansion-Cox recursion in case of ordinary polynomial splines and to Lyche's recursion in case of Tchebycheff splines [Muhlbach and Tang, Calculation of ECT-B-splines and of ECT-spline curves recursively, in preparation].There is an ECT-spline space naturally adjoint to every ECT-spline space. We also construct B-splines via generalized divided differences for this space and study relations between the two adjoint spaces.

Muhlbach, G.

2006-03-01

40

Implantable Microimagers  

PubMed Central

Implantable devices such as cardiac pacemakers, drug-delivery systems, and defibrillators have had a tremendous impact on the quality of live for many disabled people. To date, many devices have been developed for implantation into various parts of the human body. In this paper, we focus on devices implanted in the head. In particular, we describe the technologies necessary to create implantable microimagers. Design, fabrication, and implementation issues are discussed vis-à-vis two examples of implantable microimagers; the retinal prosthesis and in vivo neuro-microimager. Testing of these devices in animals verify the use of the microimagers in the implanted state. We believe that further advancement of these devices will lead to the development of a new method for medical and scientific applications.

Ng, David C.; Tokuda, Takashi; Shiosaka, Sadao; Tano, Yasuo; Ohta, Jun

2008-01-01

41

School of Computer Science and Statistics ECTS Module Descriptor  

E-print Network

Science and Statistics ECTS Module Descriptor · A project report which is more than three weeks overdueSchool of Computer Science and Statistics ECTS Module Descriptor Academic Year 2010-2011 Module in an interim report to be presented in the last week of Semester 1; (2) An execution phase, which extends from

O'Mahony, Donal E.

42

Dimensions of Power: Older Women's Experiences with Electroconvulsive Therapy (ECT)  

Microsoft Academic Search

Older women are particularly prone to being treated for depression, and, despite the controversy surrounding it, electroconvulsive therapy (ECT) has gained popularity as a treatment with this population. Research has examined the physical and cognitive changes associated with ECT but there is little understanding regarding how older women themselves experience this treatment. In order to gain better understanding into the

Alison Orr; Deborah OConnor

2005-01-01

43

Plasma-based ion implantation: a valuable technology for the elaboration of innovative materials and nanostructured thin films  

NASA Astrophysics Data System (ADS)

Plasma-based ion implantation (PBII), invented in 1987, can now be considered as a mature technology for thin film modification. After a brief recapitulation of the principle and physics of PBII, its advantages and disadvantages, as compared to conventional ion beam implantation, are listed and discussed. The elaboration of thin films and the modification of their functional properties by PBII have already been achieved in many fields, such as microelectronics (plasma doping/PLAD), biomaterials (surgical implants, bio- and blood-compatible materials), plastics (grafting, surface adhesion) and metallurgy (hard coatings, tribology), to name a few. The major advantages of PBII processing lie, on the one hand, in its flexibility in terms of ion implantation energy (from 0 to 100 keV) and operating conditions (plasma density, collisional or non-collisional ion sheath), and, on the other hand, in the easy transferrability of processes from the laboratory to industry. The possibility of modifying the composition and physical nature of the films, or of drastically changing their physical properties over several orders of magnitude makes this technology very attractive for the elaboration of innovative materials, including metastable materials, and the realization of micro- or nanostructures. A review of the state of the art in these domains is presented and illustrated through a few selected examples. The perspectives opened up by PBII processing, as well as its limitations, are discussed.

Vempaire, D.; Pelletier, J.; Lacoste, A.; Béchu, S.; Sirou, J.; Miraglia, S.; Fruchart, D.

2005-05-01

44

Rationale for the Use of CAD/CAM Technology in Implant Prosthodontics  

PubMed Central

Despite the predictable longevity of implant prosthesis, there is an ongoing interest to continue to improve implant prosthodontic treatment and outcomes. One of the developments is the application of computer-aided design and computer-aided manufacturing (CAD/CAM) to produce implant abutments and frameworks from metal or ceramic materials. The aim of this narrative review is to critically evaluate the rationale of CAD/CAM utilization for implant prosthodontics. To date, CAD/CAM allows simplified production of precise and durable implant components. The precision of fit has been proven in several laboratory experiments and has been attributed to the design of implants. Milling also facilitates component fabrication from durable and aesthetic materials. With further development, it is expected that the CAD/CAM protocol will be further simplified. Although compelling clinical evidence supporting the superiority of CAD/CAM implant restorations is still lacking, it is envisioned that CAD/CAM may become the main stream for implant component fabrication. PMID:23690778

Abduo, Jaafar; Lyons, Karl

2013-01-01

45

An Ultrasound Assisted Anchoring Technique (BoneWelding® Technology) for Fixation of Implants to Bone - A Histological Pilot Study in Sheep  

PubMed Central

The BoneWelding® Technology offers new opportunities to anchor implants within bone. The technology melted the surface of biodegradable polymer pins by means of ultrasound energy to mould material into the structures of the predrilled bone. Temperature changes were measured at the sites of implantation in an in vitro experiment. In the in vivo part of the study two types of implants were implanted in the limb of sheep to investigate the biocompatibility of the method. One implant type was made of PL-DL-lactide (PLA), the second one was a titanium core partially covered with PLA. Healing period was 2 and 6 months, with 3 sheep per group. Bone samples were evaluated radiologically, histologically and histomorphometrically for bone remodeling and inflammatory reactions. Results demonstrated mild and short temperature increase during insertion. New bone formed at the implant without evidence of inflammatory reaction. The amount of adjacent bone was increased compared to normal cancellous bone. It was concluded that the BoneWelding® Technology proved to be a biocompatible technology to anchor biodegradable as well as titanium-PLA implants in bone. PMID:19572033

Langhoff, Jens D; Kuemmerle, Jan M; Mayer, Joerg; Weber, Urs; Berra, Milica; Mueller, Jessika M; Kaestner, Sabine B; Zlinszky, Katalin; Auer, Joerg A; von Rechenberg, Brigitte

2009-01-01

46

Development of a "Self-Cleaning" Encapsulation Technology for Implantable Glucose Monitoring  

E-print Network

limiting leaching and increasing sensor lifetime. For an implanted sensor to be successful in vivo, it should exhibit long-term stability and functionality. Even biocompatible materials that have no toxic effect on surrounding tissues elicit a host response...

Gant, Rebecca M.

2011-02-22

47

A phone-assistive device based on Bluetooth technology for cochlear implant users  

Microsoft Academic Search

Hearing-impaired people, and particularly hearing-aid and cochlear-implant users, often have difficulty communicating over the telephone. The intelligibility of telephone speech is considerably lower than the intelligibility of face-to-face speech. This is partly because of lack of visual cues, limited telephone bandwidth, and background noise. In addition, cellphones may cause interference with the hearing aid or cochlear implant. To address these

Haifeng Qian; Philipos C. Loizou; Michael F. Dorman

2003-01-01

48

Electroconvulsive Therapy in Patients With Skull Defects or Metallic Implants: A Review of the Literature and Case Report  

PubMed Central

Context: Head injury is often associated with psychiatric morbidity. While it is well understood that the loss of critical areas of the brain may play a role in cognitive dysfunction and change in personality, head injury can also have profound effects on mood and cognition. The role of medications in the treatment of mood disorders associated with brain injury is well documented, and there is also evidence favoring the use of electroconvulsive therapy (ECT) in this context. However, data are limited on the use of ECT in patients with skull defects or metallic head implants. Evidence Acquisition: First, a review of the literature on use of ECT in patients with metallic head implants is provided. Electronic databases and online sites, including PubMed, Cochrane Library of Systematic Reviews, and UpToDate, were used to search for relevant articles and case reports on the use of ECT in patients with and without metallic implants in the head (1964 to 2009). The search terms electroconvulsive, electroconvulsive therapy, ECT, electroshock therapy, EST, head injury, brain injury, metallic plates, metallic implants, skull prosthesis, and depression were used interchangeably. The search produced 7 articles discussing exclusively the use of ECT in patients with a metallic skull plate. Second, the case of the successful and safe use of ECT in an individual with a previous history of brain trauma and metallic plate implantation is described. Results: Most cases of head injury are managed by neurologists and rehabilitation consultants; the more severe cases of depression and other mood disorders tend to be referred for specialist psychiatric care. With greater degrees of deficit following head injury, management becomes more complicated. Our patient showed positive results with ECT, including improvement in depressive features and resolution of suicidal ideas/plans. Conclusion: ECT is an effective and safe alternative in patients with a history of brain trauma and metallic plate implantation who subsequently develop treatment-resistant depression and associated suicidal ideas or plans refractory to management with medications. PMID:22943035

Delva, Nicholas; McRae, Harold; Campbell, Laura A.; Cole, Julie

2012-01-01

49

Estimation of Nitrogen Ion Energy in Sterilization Technology by Plasma Based Ion Implantation  

NASA Astrophysics Data System (ADS)

Plasma based ion implantation (PBII) with negative voltage pulses to the test specimen has been applied to the sterilization process as a technique suitable for three-dimensional work pieces. Pulsed high negative voltage (5 ?s pulse width, 300 pulses/s, -800 V to -15 kV) was applied to the electrode in this process at a gas pressure of 2.4 Pa of N2. We found that the PBII process, in which N2 gas self-ignitted plasma generated by only pulsed voltages is used, reduces the number of active Bacillus pumilus cell. The number of bacteria survivors was reduced by 10-5 x with 5 min exposure. Since the ion energy is the most important processing parameter, a simple method to estimate the nitrogen ion energy from distribution of nitrogen atoms in Si implanted by PBII was developed. The implanted ion energy is discussed from the SIMS in depth profiles.

Kondou, Youhei; Nakashima, Takeru; Tanaka, Takeshi; Takagi, Toshinori; Watanabe, Satoshi; Ohkura, Kensaku; Shibahara, Kentaro; Yokoyama, Shin

50

Implantable Heart Aid  

NASA Technical Reports Server (NTRS)

CPI's human-implantable automatic implantable defibrillator (AID) is a heart assist system, derived from NASA's space circuitry technology, that can prevent erratic heart action known as arrhythmias. Implanted AID, consisting of microcomputer power source and two electrodes for sensing heart activity, recognizes onset of ventricular fibrillation (VF) and delivers corrective electrical countershock to restore rhythmic heartbeat.

1984-01-01

51

Tetrode technology: advances in implantable hardware, neuroimaging, and data analysis techniques  

Microsoft Academic Search

The technical advances in hardware and software for multiunit recordings have made it easier to gather data from a large number of neurons for behavioral correlations. This paper discusses several such advances in implantable hardware, magnetic resonance imaging of electrodes in situ, and data analysis software for multiple simultaneous signals.

M. S. Jog; C. I. Connolly; Y. Kubota; D. R. Iyengar; L. Garrido; R. Harlan; A. M. Graybiel

2002-01-01

52

The Effect of Technology and Testing Environment on Speech Perception Using Telehealth with Cochlear Implant Recipients  

ERIC Educational Resources Information Center

Purpose: In this study, the authors evaluated the effect of remote system and acoustic environment on speech perception via telehealth with cochlear implant recipients. Method: Speech perception was measured in quiet and in noise. Systems evaluated were Polycom visual concert (PVC) and a hybrid presentation system (HPS). Each system was evaluated…

Goehring, Jenny L.; Hughes, Michelle L.; Baudhuin, Jacquelyn L.; Valente, Daniel L.; McCreery, Ryan W.; Diaz, Gina R.; Sanford, Todd; Harpster, Roger

2012-01-01

53

The ObjECTS: Framework for Integrated Assessment: Hybrid Modeling of Transportation  

SciTech Connect

Technology is a central issue for the global climate change problem, requiring analysis tools that can examine the impact of specific technologies with a long-term, global context. This paper describes the architecture of the ObjECTS-MiniCAM integrated assessment model, which implements a long-term, global model of energy, economy, agriculture, land-use, atmosphere, and climate change in a framework that allows the flexible incorporation of explicit technology detail. We describe the implementation of a ''bottom-up'' representation of the transportation sector as an illustration of this approach, in which the resulting hybrid model is fully integrated, internally consistent and theoretically compatible with the regional and global modeling framework. The analysis of the transportation sector presented here supports and clarifies the need for a comprehensive strategy promoting advanced vehicle technologies and an economy-wide carbon policy to cost-effectively reduce carbon emissions from the transportation sector in the long-term.

Kim, Son H.; Edmonds, James A.; Lurz, Joshua; Smith, Steven J.; Wise, Marshall A.

2006-09-01

54

School of Computer Science and Statistics ECTS Module Descriptor  

E-print Network

School of Computer Science and Statistics ECTS Module Descriptor Academic Year 2011-2012 Module (Bernoulli) , Discrete Uniform, Binomial, Poisson, and o for continuous random variables, the Uniform, Normal will be introduced and confidence intervals will be mentioned, but formal study of statistical inference

O'Mahony, Donal E.

55

Optical absorption spectra and geometric e ects in higher fullerenes  

E-print Network

Optical absorption spectra and geometric e ects in higher fullerenes (Running head: Optical absorption in higher fullerenes) Kikuo Harigaya and Shuji Abe Physical Science Division, Electrotechnical and higher fullerenes, including isomers of C76, C78, and C84, are theoretically investigated. We use a tight

Harigaya, Kikuo

56

Engineering the heart: Evaluation of conductive nanomaterials for improving implant integration and cardiac function  

PubMed Central

Recently, carbon nanotubes together with other types of conductive materials have been used to enhance the viability and function of cardiomyocytes in vitro. Here we demonstrated a paradigm to construct ECTs for cardiac repair using conductive nanomaterials. Single walled carbon nanotubes (SWNTs) were incorporated into gelatin hydrogel scaffolds to construct three-dimensional ECTs. We found that SWNTs could provide cellular microenvironment in vitro favorable for cardiac contraction and the expression of electrochemical associated proteins. Upon implantation into the infarct hearts in rats, ECTs structurally integrated with the host myocardium, with different types of cells observed to mutually invade into implants and host tissues. The functional measurements showed that SWNTs were essential to improve the performance of ECTs in inhibiting pathological deterioration of myocardium. This work suggested that conductive nanomaterials hold therapeutic potential in engineering cardiac tissues to repair myocardial infarction. PMID:24429673

Zhou, Jin; Chen, Jun; Sun, Hongyu; Qiu, Xiaozhong; Mou, Yongchao; Liu, Zhiqiang; Zhao, Yuwei; Li, Xia; Han, Yao; Duan, Cuimi; Tang, Rongyu; Wang, Chunlan; Zhong, Wen; Liu, Jie; Luo, Ying; (Mengqiu) Xing, Malcolm; Wang, Changyong

2014-01-01

57

Random e ects compound Poisson model to represent data with extra zeros  

E-print Network

, Importance Sampling, Compound Poisson Process, Random E#11;ect Model, zero-in ated Data 2008 MSC: 62F12, 62PRandom e#11;ects compound Poisson model to represent data with extra zeros Marie-Pierre #19 Brunswick,Canada Abstract This paper describes a compound Poisson-based random e#11;ects structure for mod

Recanati, Catherine

58

Budapest University of Technology and Economics An ECTS Guide  

E-print Network

@yahoo.fr China Grand Education Group Dawn Zhang Room 720 Quingdao, World Trade Center, Building B, No.6 not only on our responsiveness to the needs of a continuously changing world, but also on more than 225 pro- fessors and students from all over the world. We are proud of our international professors

Ráth, Balázs

59

A method and technical equipment for an acute human trial to evaluate retinal implant technology  

NASA Astrophysics Data System (ADS)

This paper reports on methods and technical equipment to investigate the epiretinal stimulation of the retina in blind human subjects in acute trials. Current is applied to the retina through a thin, flexible microcontact film (microelectrode array) with electrode diameters ranging from 50 to 360 µm. The film is mounted in a custom-designed surgical tool that is hand-held by the surgeon during stimulation. The eventual goal of the work is the development of a chronically implantable retinal prosthesis to restore a useful level of vision to patients who are blind with outer retinal degenerations, specifically retinitis pigmentosa and macular degeneration.

Hornig, Ralf; Laube, Thomas; Walter, Peter; Velikay-Parel, Michaela; Bornfeld, Norbert; Feucht, Matthias; Akguel, Harun; Rössler, Gernot; Alteheld, Nils; Lütke Notarp, Dietmar; Wyatt, John; Richard, Gisbert

2005-03-01

60

Packaging and Non-Hermetic Encapsulation Technology for Flip Chip on Implantable MEMS Devices  

PubMed Central

We report here a successful demonstration of a flip-chip packaging approach for a microelectromechanical systems (MEMS) device with in-plane movable microelectrodes implanted in a rodent brain. The flip-chip processes were carried out using a custom-made apparatus that was capable of the following: 1) creating Ag epoxy microbumps for first-level interconnect; 2) aligning the die and the glass substrate; and 3) creating non-hermetic encapsulation (NHE). The completed flip-chip package had an assembled weight of only 0.5 g significantly less than the previously designed wire-bonded package of 4.5 g. The resistance of the Ag bumps was found to be negligible. The MEMS micro-electrodes were successfully tested for its mechanical movement with microactuators generating forces of 450 ?N with a displacement resolution of 8.8 ?m/step. An NHE on the front edge of the package was created by patterns of hydrophobic silicone microstructures to prevent contamination from cerebrospinal fluid while simultaneously allowing the microelectrodes to move in and out of the package boundary. The breakdown pressure of the NHE was found to be 80 cm of water, which is significantly (4.5–11 times) larger than normal human intracranial pressures. Bench top tests and in vivo tests of the MEMS flip-chip packages for up to 75 days showed reliable NHE for potential long-term implantation. PMID:24431925

Sutanto, Jemmy; Anand, Sindhu; Sridharan, Arati; Korb, Robert; Zhou, Li; Baker, Michael S.; Okandan, Murat; Muthuswamy, Jit

2013-01-01

61

Implantable technology for long-term delivery of nalmefene for treatment of alcoholism.  

PubMed

Pharmacotherapy treatment for alcoholism is limited by poor compliance, adverse effects, and fluctuating drug levels after bolus administration. A long-term delivery system would improve upon these limitations. The current study describes the characterization of a sustained release implant containing nalmefene, an opioid antagonist, for treatment of alcoholism. Nalmefene was blended with ethylene vinyl acetate (EVA), extruded into 2.8 mm x 27 mm rods, and coated with EVA to optimize release. In vitro release was determined by HPLC, and in vivo release characteristics after subcutaneous implantation into rats were determined by LC-MS/MS analyses. Extrusion produced rods containing 80.09 +/- 6.0 mg nalmefene. In vitro release was high from the uncoated rods, and they were depleted of drug fairly quickly; however EVA coatings maintained release over longer periods. The 25 wt.% coated rods provided in vitro release of 0.36 mg/day/rod, and in vivo release of 0.29 mg/day/rod over 6 months, and showed dose-dependent nalmefene plasma concentrations (one rod: 3.33 +/- 0.56 ng/ml, three rods: 10.19 +/- 2.31 ng/ml). After explantation, nalmefene plasma concentrations were undetectable by 6 h. A sustained release nalmefene rod provides 6 months of drug with no adverse effects. PMID:15363499

Costantini, Lauren C; Kleppner, Sofie R; McDonough, Joseph; Azar, Marc R; Patel, Raj

2004-09-28

62

Cochlear Implants  

MedlinePLUS

... Need to Know Before, During, & After Implant Surgery Recalls and Safety Cochlear Implants View movie of the ... cochlear implants, and provide news about cochlear implant recalls and safety issues. You can find information here ...

63

Space Science Technology Health General Sci-fi & Gaming Oddities International Business Politics Education Entertainment Sports Implant Maps Heart Electrical Activity In  

E-print Network

Space Science Technology Health General Sci-fi & Gaming Oddities International Business Politics: Thursday, 25 March 2010, 08:15 CDT Next-Generation Devices Pave Way for Applications in Cardiology of implantable device for measuring the heart's electrical output that they say is a vast improvement over

Rogers, John A.

64

Building Better Bones Researchers are advancing medical bone implant technology with rapid prototyping techniques and digitally designed zirconia molds  

Microsoft Academic Search

spects of rapid prototyping and ti- tanium casting have been com- bined in a system to produce tita- nium replicas of human bones. Although titanium is currently used for bone replacement, implants are simple geometric approximations of the bone shape. Mismatches between implants and real bone often cause stress con- centrations and result in premature implant failure. If more accurate

NICOLE HARLAN; REUBEN REYES; DAVID BOURELL

2000-01-01

65

Implant Chips  

NSDL National Science Digital Library

A group of eight people, including all members of one Florida family, had an implant chip, roughly the size of a grain of rice, injected under their skin on Friday, May 10. Manufactured by Applied Digital Solutions (ADS), the chips store a special identification number that enables the retrieval of personal and medical information. In the event of a medical emergency, a special handheld scanner activates the dormant digital implant, which provides identification data with which medical personnel can query ADS's database, the location of the patient's medical records. Alzheimer's patients seem to be the most promising market for this technology, even though other people, like the Florida family, hope to benefit from it as well. Another product that ADS offers is called Digital Angel, a wearable global positioning system (GPS) device that, among other things, can track in real time the wearer's physical movements. In the future, ADS is planning to release a product that will utilize both of these technologies: an implanted GPS-enabled chip. Unlike VeriChip, though, the GPS-enabled implant would require Food and Drug Administration (FDA) approval, meaning the US market won't see its introduction until after FDA testing. Many organizations, ranging from privacy advocates to religious groups, have already denounced VeriChip and its eventually successors, associated them with "Big Brother" and the biblical "Mark of the Beast."To read about the eight people that received their implants, look at the first and second sites, articles from the Los Angeles Times and Miami Herald respectively. For a non-US perspective, view the news story posted by the British Broadcasting Company (BBC). The fourth site, an extensive analysis of the subject from ABC News, should give readers a broader understanding of implanted chips and their potential uses. Two sites from ADS are next -- VeriChip's product pages and the press release that details a FDA's decision regarding VeriChip in April, 2002. Finally, the last two sites give more information on Digital Angel and a sample of GPS technology already in use.

Schroeder, Ted.

2002-01-01

66

The Effect of Technology and Testing Environment on Speech Perception using Telehealth with Cochlear Implant Recipients  

PubMed Central

Purpose The current study evaluated the effect of remote system and acoustic environment on speech perception via telehealth with cochlear implant recipients. Method Speech perception was measured in quiet and in noise. Systems evaluated were: Polycom visual concert (PVC) and a hybrid presentation system (HPS). Each system was evaluated in a sound-treated booth and a quiet office. Results For speech in quiet, there was a significant effect of environment with better performance in the booth compared to the office; there was no effect of system (PVC or HPS). Speech in noise revealed a significant interaction between environment and system. Subjects’ performance was poorer for PVC in the office while performance in the sound booth was not significantly different for the two systems. Results from the current study were compared to results for the same group of subjects from an earlier study; results suggested poorer performance at remote sites in the previous study was primarily due to environment, not system. Conclusions Speech perception was best when evaluated in a sound-treated booth. HPS was superior for speech in noise in a reverberant environment. Future research should focus on modifications to non sound-treated environments for telehealth service delivery in rural areas. PMID:22411283

Goehring, Jenny L.; Hughes, Michelle L.; Baudhuin, Jacquelyn L.; Valente, Daniel L.; McCreery, Ryan W.; Diaz, Gina R.; Sanford, Todd; Harpster, Roger

2012-01-01

67

First long term in vivo study on subdurally implanted micro-ECoG electrodes, manufactured with a novel laser technology.  

PubMed

A novel computer aided manufacturing (CAM) method for electrocorticography (ECoG) microelectrodes was developed to be able to manufacture small, high density microelectrode arrays based on laser-structuring medical grade silicone rubber and high purity platinum. With this manufacturing process, we plan to target clinical applications, such as presurgical epilepsy monitoring, functional imaging during cerebral tumor resections and brain-computer interface control in paralysed patients, in the near future. This paper describes the manufacturing, implantation and long-term behaviour of such an electrode array. In detail, we implanted 8-channel electrode arrays subdurally over rat cerebral cortex over a period of up to 25 weeks. Our primary objective was to ascertain the electrode's stability over time, and to analyse the host response in vivo. For this purpose, impedance measurements were carried out at regular intervals over the first 18 weeks of the implantation period. The impedances changed between day 4 and day 7 after implantation, and then remained stable until the end of the implantation period, in accordance with typical behaviour of chronically implanted microelectrodes. A post-mortem histological examination was made to assess the tissue reaction due to the implantation. A mild, chronically granulated inflammation was found in the area of the implant, which was essentially restricted to the leptomeninges. Overall, these findings suggest that the concept of the presented ECoG-electrodes is promising for use in long-term implantations. PMID:20838900

Henle, C; Raab, M; Cordeiro, J G; Doostkam, S; Schulze-Bonhage, A; Stieglitz, T; Rickert, J

2011-02-01

68

Materials processing towards development of rapid prototyping technology for manufacturing biomedical implants  

NASA Astrophysics Data System (ADS)

Materials processing towards development of fused deposition of materials (FDM) method for manufacturing biomedical implants has been studied experimentally. Main processing steps consisted of thermoplastic binder development in the ethylene vinyl acetate (EVA)-microcrystalline wax system, feedstock extrusion, characterization and optimization of binder degradation, and sintering of calcium deficient hydroxyapatite. Differential scanning calorimetry (DSC) revealed that the melting index (MI) of the copolymer affects the temperature location of the solidification exotherm, whereas the effect on the temperature location of the melting endotherm was negligible. Nonisothermal measurement of viscosity of different blends as a function of VA content of the EVA component revealed that the microcrystalline wax is compatible with 25--14% VA-containing EVA grades. Further DSC analysis revealed that co-crystallization leads to compatible EVA-microcrystalline wax blends. A typical binder formulation that was developed in the present work has a viscosity of about 700 cP at 140°C, a compressive yield strength of 6 MPa and an elastic modulus of about 600 MPa, and contained 15--20% EVA and 80--85% microcrystalline wax. Various filaments with a nominal diameter of 1.8 mm were extruded by using such a binder, and calcium pyro-phosphate powder that had a distribution modulus of about 0.37. Measurement of physical dimensions of the filament revealed that fluid state can be achieved in the filaments. Simultaneous thermal analysis of degradation characteristics of the typical binder formulations revealed that degradation sequence is oxidation of the hydrocarbons, evaporation of the hydrocarbons, degradation of the vinyl acetate, and degradation of the ethylene chain. A rate controlled binder removal system was developed and used in order to optimize the binder removal schedule. Sintering of gel-cast calcium hydroxyapatite was studied by means of thermal analysis, XRD, mechanical testing, and SEM, both for sub-micron and the agglomerated powder type. Transformation temperatures of tri-calcium phosphate upon cooling were determined as 1475°C for (alpha' to alpha, 1190°C for alpha to beta, and 800--700°C range for beta to hydroxy-oxyapatite transformation. Dilatometry revealed that dimensional change reaches to saturation at 1200°C. Mechanical testing of the parts sintered at 1200--1500°C revealed that compressive strength in the 2--10 MPa range was achieved.

Pekin, Senol

2000-10-01

69

Cochlear Implants (For Parents)  

MedlinePLUS

Sometimes called a "bionic ear," the cochlear implant offers the hope of regaining or restoring the ability to sense sound for some people ... does may help kids better understand their new bionic ear and the cool technology behind it that ...

70

A novel root analogue dental implant using CT scan and CAD/CAM: selective laser melting technology.  

PubMed

Direct laser metal forming (DLMF) is a new technique which allows solids with complex geometry to be produced by annealing metal powder microparticles in a focused laser beam, according to a computer-generated three-dimensional (3D) model. For dental implants, the fabrication process involves the laser-induced fusion of titanium microparticles, in order to build, layer by layer, the desired object. Modern computed tomography (CT) acquisition and 3D image conversion, combined with the DLMF process, allows the fabrication of custom-made, root-analogue implants (RAI), perfect copies of the radicular units that need replacing. This report demonstrates the successful clinical use of a custom-made, root-analogue DLMF implant. CT images of the residual non-restorable root of a right maxillary premolar were acquired and modified with specific software into a 3D model. From this model, a custom-made, root-analogue, DLMF implant was fabricated. Immediately after tooth extraction, the root-analogue implant was placed in the extraction socket and restored with a single crown. At the 1-year follow-up examination, the custom-made implant showed almost perfect functional and aesthetic integration. The possibility of fabricating custom-made, root-analogue DLMF implants opens new interesting perspectives for immediate placement of dental implants. PMID:22377004

Figliuzzi, M; Mangano, F; Mangano, C

2012-07-01

71

Dual-Thickness Gate Oxidation Technology with Halogen\\/Xenon Implantation for Embedded Dynamic Random Access Memories  

Microsoft Academic Search

We investigated the enhanced oxidation effect of using silicon (Si) implanted with fluorine (F), iodine (I), and xenon (Xe) before gate oxidation. I and Xe, which result in shallower implants because of their higher mass numbers, were expected to be less damaging to the Si substrate. The resultant increase in oxide thickness was found to be 20%, 80%, and 50%

Taro Sugizaki; Atsushi Murakoshi; Yoshio Ozawa; Toshiro Nakanishi; Kyoichi Suguro

2001-01-01

72

Scale e ects related to ow in rough fractures Y. M eheust and J. Schmittbuhl  

E-print Network

Scale e#11;ects related to ow in rough fractures Y. M#19;eheust and J. Schmittbuhl #19; Ecole;ects related to ow in rough fractures Y. M#19;eheust and J. Schmittbuhl #19; Ecole Normale Sup#19;erieure, Paris, France Received { Accepted Abstract. A numerical fracture ow simulation based

Schmittbuhl, Jean

73

The E ect of Barriers on The Tidal Range in Yong Ming Tang  

E-print Network

interest in constructing tidal barrages, either to control the tide or to extract power. CorrespondinglyThe E ect of Barriers on The Tidal Range in Estuaries Yong Ming Tang Abstract Numerical simulations of the shallow water equations are used to study the e ect of topographic barriers on the tidal range

74

LC-TH-2003-046 Discriminating graviton exchange e ects from other  

E-print Network

LC-TH-2003-046 Discriminating graviton exchange e#11;ects from other new physics scenarios in e + e the e#11;ects of graviton exchange from other new physics in high energy e + e annihilation into fermion]; anomalous gauge boson couplings (AGC) [9]; virtual Kaluza{Klein (KK) graviton exchange in the context

75

Discriminating graviton exchange e ects from other new physics scenarios in e  

E-print Network

Discriminating graviton exchange e#11;ects from other new physics scenarios in e + e collisions P;ects of graviton exchange from other new physics in high energy e + e annihilation into fermion]; anomalous gauge boson couplings (AGC) [9]; virtual Kaluza{Klein (KK) graviton exchange in the context

76

Ictal EEG fractal dimension in ECT predicts outcome at 2 weeks in schizophrenia.  

PubMed

Studies of electroconvulsive therapy (ECT) have found an association between ictal electroencephalographic (EEG) measures and clinical outcome in depression. Such studies are lacking in schizophrenia. Consenting schizophrenia patients receiving ECT were assessed using the Brief Psychiatric Rating Scale (BPRS) before and 2 weeks after the start of ECT. The patients' seizure was monitored using EEG. In 26 patients, completely artifact-free EEG derived from the left frontal-pole (FP1) channel and electrocardiography (ECG) were available. The fractal dimension (FD) was computed to assess 4-s EEG epochs, and the maximal value from the earliest ECT session (2nd, 3rd or 4th) was used for analysis. There was a significant inverse correlation between the maximum FD and the total score following 6th ECT. An inverse Inverse correlation was also observed between the maximum FD and the total number of ECTs administered as well as the maximum heart rate (HR) and BPRS scores following 6th ECT. In patients with schizophrenia greater intensity of seizures (higher FD) during initial sessions of ECT is associated with better response at the end of 2 weeks. PMID:23261182

Abhishekh, Hulegar A; Thirthalli, Jagadisha; Manjegowda, Anusha; Phutane, Vivek H; Muralidharan, Kesavan; Gangadhar, Bangalore N

2013-09-30

77

Shape Invariant Modelling of Circadian Rhythms with Random E#ects and  

E-print Network

Shape Invariant Modelling of Circadian Rhythms with Random E#ects and Smoothing Spline ANOVA dynamics such as circadian rhythms. Under the assumption that the expected response functions of all methods to a real data set to investigate disease e#ects on circadian rhythms of cortisol, a hormone

Wang, Yuedong

78

OIL IN THE OPEN WATER Oil in the open water may a ect the health of  

E-print Network

OIL IN THE OPEN WATER Oil in the open water may a ect the health of microscopic plants and animals. Far beneath the surface, corals and other deepwater communities might also be a ected. OIL AND HUMAN AND SEDIMENTS · Water quality surveys · Transect surveys to detect submerged oil · Oil plume modeling · Sediment

79

Stark E ect of Interactive Electron-hole pairs in Spherical Semiconductor Quantum Dots  

E-print Network

Stark E#11;ect of Interactive Electron-hole pairs in Spherical Semiconductor Quantum Dots B model, on the quantum-con#12;nement Stark e#11;ects for spherical semiconducting quantum dots of quantum dot sizes. PACS numbers: 71.35.-y, 71.70.Ej Submitted to: Journal of Physics: Condensed Matter z

Recanati, Catherine

80

EXTRACTION DE CONNAISSANCES PARTIR DES DONNEES ET DES TEXTES (ECD ET ECT "DATA & TEXT MINING")  

E-print Network

1 EXTRACTION DE CONNAISSANCES � PARTIR DES DONNEES ET DES TEXTES (ECD ET ECT "DATA & TEXT MINING'Extraction de Connaissances à partir de Textes (ECT, "Text Mining") comme un descendant direct de l'Extraction de Connaissances à partir de Données (ECD, "Data Mining"). Le point fondamental qui distingue ces

Spagnolo, Filippo

81

O.S.U.-T.C.G. Report No. 107 The Jahn-Teller E ect  

E-print Network

. It has, however, proven to be very di cult to demonstrate this e ect experimentally. Van Vleck 2." But as Ballhausen states in his book 3], the e ect is very di cult to nd when one does wish to demonstrate it. As we

Pitzer, Russell M.

82

Modelling the e#ects of air pollution on health using Bayesian Dynamic Generalised Linear Models  

E-print Network

Modelling the e#ects of air pollution on health using Bayesian Dynamic Generalised Linear Models 1 Introduction The potential detrimental e#ects of ambient air pollution is a major issue in public (2004)). Large multi­city studies such as `Air pollution and health: a European approach' (APHEA

Bath, University of

83

Is electroconvulsive therapy (ECT) ever ethically justified? If so, under what circumstances.  

PubMed

The debate about ECT in Ireland in recent times has been vibrant and often polarised. The uniqueness of the Irish situation is that the psychiatric profession is protected by legislation whereby ECT treatment can be authorized by two consultant psychiatrists without the consent of the patient. This paper will consider if ECT is ever ethically justified, and if so, under what circumstances. The proposal is to investigate ECT from an ethical perspective with reference to the UNESCO Universal Declaration on Bioethics and Human Rights. The enquiry will begin with an historical context to the origin and development of ECT as a treatment for severe mental illness. The application of various ethical principles will be considered in conjunction with the relevant literature before arriving at a conclusion. PMID:22797936

Stefanazzi, Mary

2013-03-01

84

Dental Implant Systems  

PubMed Central

Among various dental materials and their successful applications, a dental implant is a good example of the integrated system of science and technology involved in multiple disciplines including surface chemistry and physics, biomechanics, from macro-scale to nano-scale manufacturing technologies and surface engineering. As many other dental materials and devices, there are crucial requirements taken upon on dental implants systems, since surface of dental implants is directly in contact with vital hard/soft tissue and is subjected to chemical as well as mechanical bio-environments. Such requirements should, at least, include biological compatibility, mechanical compatibility, and morphological compatibility to surrounding vital tissues. In this review, based on carefully selected about 500 published articles, these requirements plus MRI compatibility are firstly reviewed, followed by surface texturing methods in details. Normally dental implants are placed to lost tooth/teeth location(s) in adult patients whose skeleton and bony growth have already completed. However, there are some controversial issues for placing dental implants in growing patients. This point has been, in most of dental articles, overlooked. This review, therefore, throws a deliberate sight on this point. Concluding this review, we are proposing a novel implant system that integrates materials science and up-dated surface technology to improve dental implant systems exhibiting bio- and mechano-functionalities. PMID:20480036

Oshida, Yoshiki; Tuna, Elif B.; Aktoren, Oya; Gencay, Koray

2010-01-01

85

ePUB: Modellierung Molecular Life Sciences Master Major 90 ECTS-Credits with special qualification in Microbio/  

E-print Network

) (Wahlpflichtprüfung) (ab WS05/06) Eucaryotic gene expression (3.00 ECTS) (Wahlpflichtprüfung) Forensic chemistry to write in English (2.00 ECTS) (Wahlpflichtprüfung) (WS05/06 bis HS07) Advanced medicinal chemistry - from.50 ECTS) (Wahlpflichtprüfung) (ab HS09) Basic medicinal chemistry - principles of drug action (1.50 ECTS

Richner, Heinz

86

Current trends in dental implants  

PubMed Central

Tooth loss is very a very common problem; therefore, the use of dental implants is also a common practice. Although research on dental implant designs, materials and techniques has increased in the past few years and is expected to expand in the future, there is still a lot of work involved in the use of better biomaterials, implant design, surface modification and functionalization of surfaces to improve the long-term outcomes of the treatment. This paper provides a brief history and evolution of dental implants. It also describes the types of implants that have been developed, and the parameters that are presently used in the design of dental implants. Finally, it describes the trends that are employed to improve dental implant surfaces, and current technologies used for the analysis and design of the implants. PMID:24868501

Gaviria, Laura; Salcido, John Paul; Guda, Teja

2014-01-01

87

DATE OF REQUEST: NVLAP LAB CODE: ECT APPLICATION ADDENDUM #3 (2007-05-25) PAGE 1 OF 1  

E-print Network

-1 ECT-MIL-STD Military Standard MIL STD 461 / 462 ECT-SAFETY RF Safety Specific Absorbtion Rate (SAR-IMMUN Electromagnetic Immunity (i.e., ESD, radiated immunity, surge, etc.) IEC 61000-4-2 ECT-PS Product Safety IEC60601

Magee, Joseph W.

88

Noise reduction technologies implemented in head-worn preprocessors for improving cochlear implant performance in reverberant noise fields.  

PubMed

The purpose of this study was to investigate whether a multichannel adaptive directional microphone and a modulation-based noise reduction algorithm could enhance cochlear implant performance in reverberant noise fields. A hearing aid was modified to output electrical signals (ePreprocessor) and a cochlear implant speech processor was modified to receive electrical signals (eProcessor). The ePreprocessor was programmed to flat frequency response and linear amplification. Cochlear implant listeners wore the ePreprocessor-eProcessor system in three reverberant noise fields: 1) one noise source with variable locations; 2) three noise sources with variable locations; and 3) eight evenly spaced noise sources from 0° to 360°. Listeners' speech recognition scores were tested when the ePreprocessor was programmed to omnidirectional microphone (OMNI), omnidirectional microphone plus noise reduction algorithm (OMNI + NR), and adaptive directional microphone plus noise reduction algorithm (ADM + NR). They were also tested with their own cochlear implant speech processor (CI_OMNI) in the three noise fields. Additionally, listeners rated overall sound quality preferences on recordings made in the noise fields. Results indicated that ADM+NR produced the highest speech recognition scores and the most preferable rating in all noise fields. Factors requiring attention in the hearing aid-cochlear implant integration process are discussed. PMID:22750449

Chung, King; Nelson, Lance; Teske, Melissa

2012-09-01

89

Electrochemical-treeing (ECT) structures in high-voltage cable insulation  

NASA Astrophysics Data System (ADS)

Dyeing and microscope techniques were used to study the influence on ECT conditions of the type of insulation and of the crosslinking technique. The ECT-structures produced under laboratory conditions resembled those found in cables after years of service. Results show that stressing field strength has an accelerating influence. Frequency, type of electrolyte and conductor material have no influence. The moisture content of the insulation and of the surroundings influence the growth of ECT-structures. The electrical breakdown strength of PE- and XLPE-Insulated model cables decreases with duration of water immersion and of electrical prestressing.

Henkel, H. J.; Mueller, N.; Kalkner, W.; Hans, H.; Sander, G.; Vanolshausen, R.; Vogel, U.

1983-05-01

90

Cochlear Implants  

MedlinePLUS

... clinic for an evaluation. The implant team (otolaryngologist, audiologist, nurse, and others) will determine your candidacy for ... for the implant procedure. Hearing (audiologic) evaluation: The audiologist performs extensive hearing tests to find out how ...

91

Breast Implants  

MedlinePLUS

... Safety Data on Silicone Gel-Filled Breast Implants (Press Announcement) [ARCHIVED] Breast Implant Guidance for Industry (2006) Post Approval Studies Webpage Freedom of Information Requests Page Last Updated: 09/17/ ...

92

Cochlear Implants  

MedlinePLUS

A cochlear implant is a small, complex electronic device that can help to provide a sense of sound. People who are ... of-hearing can get help from them. The implant consists of two parts. One part sits on ...

93

QED E ects on Inner Shells of Heavy W. R. Johnson  

E-print Network

QED E#11;ects on Inner Shells of Heavy Atoms W. R. Johnson #3; Department of Physics, University on this subject by Johnson and Cheng. [2] The experimental binding energy of a K-shell electron in a heavy atom

Johnson, Walter R.

94

Severe agitation in severe early-onset Alzheimer’s disease resolves with ECT  

PubMed Central

Dementia-related behavioral disturbances are mostly treated with antipsychotics; however, the observed beneficial effects are modest and the risk of serious adverse effects high. We report the case of a 57-year-old woman with severe early-onset Alzheimer’s disease and severe agitation, whom we treated with electroconvulsive therapy (ECT). A significant clinical improvement was achieved over eight ECT sessions, which were tolerated well without cognitive worsening, and lasted approximately 3 months. Our case demonstrates the safe and effective use of ECT in pharmacotherapy-resistant severe agitation in Alzheimer’s disease. The risk–benefit profile of ECT for dementia-related agitation should be further investigated in clinical trials.

Aksay, Suna Su; Hausner, Lucrezia; Frölich, Lutz; Sartorius, Alexander

2014-01-01

95

A case of atypical tardive seizure activity during an initial ECT titration series.  

PubMed

Electroconvulsive therapy (ECT) has been used in this country for more than 70 years, is still the most effective treatment in all of psychiatry, and is considered a very safe procedure to have under general anesthesia. Although most patients tolerate this procedure very well without complications, prolonged and/or tardive seizures or even status epilepticus can develop, which is a rare but serious complication of ECT. Tardive seizures are typically associated with electroencephalographic evidence of ictal activity and motor manifestations of the tonic-clonic activity. Whereas there are instances of nonconvulsive status epilepticus after ECT, this is the first report of a patient developing autonomic and motor manifestations of a tardive seizure without electroencephalographic evidence of seizure activity during the initial titration series to establish seizure threshold for a course of ECT. PMID:23845940

Thisayakorn, Paul; Karim, Yasser; Yamada, Thoru; McCormick, Laurie M

2014-03-01

96

The Radiation Belt Storm Probes (RBSP) Energetic Particle, Composition, and Thermal Plasma (ECT) Instrument Suite  

NASA Astrophysics Data System (ADS)

The Energetic particle, Composition, and Thermal plasma (ECT) instrument suite was selected recently by NASA as part of the Radiation Belt Storm Probe (RBSP) mission. In this presentation, we summarize the RBSP-ECT science investigation. The ECT suite contains a well-proven complement of particle instruments to ensure the highest quality measurements in the inner magnetosphere. The coordinated ECT particle measurements, analyzed in combination with fields and waves observations and state-of-the-art theory and modeling, are required for understanding the acceleration, global distribution, and variability of radiation belt electrons and ions, key science objectives of NASA's Living With a Star program and the RBSP mission. ECT has four science objectives, which consolidate the eight prioritized RBSP mission objectives. They are: (1) determine the physical processes that produce radiation belt enhancements; (2) determine the dominant mechanisms for relativistic electron loss; (3) determine how the inner magnetospheric plasma environment controls radiation belt acceleration/loss; and, (4) develop empirical and physical models for understanding/predicting radiation belt space weather effects. In this poster, we present an overview of the science and measurements goals of the ECT suite as well as the instruments required to achieve those goals.

Spence, H. E.; Kepko, E.; Reeves, G.; Funsten, H.; Thomsen, M.; Henderson, M.; Friedl, R.; Skoug, R.; Jordanova, V.; Fennell, J.; Blake, J. B.; Clemmons, J.; O'Brien, T.; Green, J.; Onsager, T.; Elkington, S.; Baker, D.; Li, X.; Goldstein, J.; Young, D.; Jahn, J.; Thorne, R.; Hudson, M.; Horne, R.; Bourdarie, S.; Mann, I.

2006-12-01

97

MicroRNA and implantation.  

PubMed

We provide a review of microRNA (miRNA) related to human implantation which shows the potential diagnostic role of miRNAs in impaired endometrial receptivity, altered embryo development, implantation failure after assisted reproduction technology, and in ectopic pregnancy and pregnancies of unknown location. MicroRNAs may be emerging diagnostic markers and potential therapeutic tools for understanding implantation disorders. However, further research is needed before miRNAs can be used in clinical practice for identifying and treating implantation failure. PMID:24882617

Galliano, Daniela; Pellicer, Antonio

2014-06-01

98

Ion Implantation  

NASA Astrophysics Data System (ADS)

In this tutorial we describe the basic principles of the ion implantation technique and we demonstrate that emission Mössbauer spectroscopy is an extremely powerful technique to investigate the atomic and electronic configuration around implanted atoms. The physics of dilute atoms in materials, the final lattice sites and their chemical state as well as diffusion phenomena can be studied. We focus on the latest developments of implantation Mössbauer spectroscopy, where three accelerator facilities, i.e., Hahn-Meitner Institute Berlin, ISOLDE-CERN and RIKEN, have intensively been used for materials research in in-beam and on-line Mössbauer experiments immediately after implantation of the nuclear probes.

Langouche, G.; Yoshida, Y.

99

Endodontic implants  

PubMed Central

Endodontic implants were introduced back in 1960. Endodontic implants enjoyed few successes and many failures. Various reasons for failures include improper case selection, improper use of materials and sealers and poor preparation for implants. Proper case selection had given remarkable long-term success. Two different cases are being presented here, which have been treated successfully with endodontic implants and mineral trioxide aggregate Fillapex (Andreaus, Brazil), an MTA based sealer. We suggest that carefully selected cases can give a higher success rate and this method should be considered as one of the treatment modalities.

Yadav, Rakesh K.; Tikku, A. P.; Chandra, Anil; Wadhwani, K. K.; Ashutosh kr; Singh, Mayank

2014-01-01

100

Oxygen implanter for simox  

Microsoft Academic Search

Interest in silicon or) insulator (SOI) technology has led to the development of several alternatives to silicon on sapphire. One of the most promising techniques makes use of an ion implanter to form a buried oxide layer directly in the silicon substrate. To have useful single crystalline silicon on top of the oxide layer, it is necessary to do the

M. Guerra; V. Benveniste; G. Ryding; D. H. Douglas-Hamilton; M. Reed; G. Gagne; A. Armstrong; M. Mack

1985-01-01

101

Ion implantation in semiconductors  

Microsoft Academic Search

Ion implantation is being applied extensively to silicon device technology. Two principle features are utilized- 1) charge control in MOS structures for threshold shift, autoregistration, and complementary wells and 2) distribution control in microwave and bipolar structures. Another feature that has not been extensively exploited is to combine the advantages of the high resolution capabilities of electric beam pattern delineation

James W. Mayer

1973-01-01

102

Students' Factors Affecting Undergraduates' Perceptions of their Teaching and Learning Process within ECTS Experience  

PubMed Central

Introduction: In the present study, we investigated the potential factors that influenced the level of students satisfaction with the teaching–learning process (TLP), from the perspective of students participating in the European Credit Transfer System (ECTS) experience. Method: A total of 1490 students from the Universities of Almería and Granada (Spain) participated in an evaluation of their class discipline area. They completed the new revised protocol for evaluating the ECTS experience. Analyses of variance were carried out, taking the following factors as independent variables: student's grade average, year in school, study discipline, credit load in terms of ECTS credits assigned to a subject, the e-learning approach. Perception of the TLP was used as the dependent variable. Results: The data analyses showed variability of the degree of statistically significance among the factors that influenced students’ perceptions of the TLP. These factors included: Student's grade average (in favor of high performers), year in school (in favor of earlier years), ECTS load (in favor of subjects with a medium load of credits), and e-learning (in favor of its use). These research findings provided evidence to explore the delineation of a potential profile of factors that trigger a favorable perception of the TLP. Discussion and Conclusion: The present findings certainly have implications to deepen our understanding of the core beliefs, commitment, and the experience in shaping the implementation of the European Higher Education Area through the ECTS. PMID:21713171

la Fuente, Jesus De; Cardelle-Elawar, Maria; Peralta, F. Javier; Sanchez, M. Dolores; Martinez-Vicente, Jose Manuel; Zapata, Lucia

2010-01-01

103

Semiconductor Ion Implanters  

NASA Astrophysics Data System (ADS)

In 1953 the Raytheon CK722 transistor was priced at 7.60. Based upon this, an Intel Xeon Quad Core processor containing 820,000,000 transistors should list at 6.2 billion! Particle accelerator technology plays an important part in the remarkable story of why that Intel product can be purchased today for a few hundred dollars. Most people of the mid twentieth century would be astonished at the ubiquity of semiconductors in the products we now buy and use every day. Though relatively expensive in the nineteen fifties they now exist in a wide range of items from high-end multicore microprocessors like the Intel product to disposable items containing `only' hundreds or thousands like RFID chips and talking greeting cards. This historical development has been fueled by continuous advancement of the several individual technologies involved in the production of semiconductor devices including Ion Implantation and the charged particle beamlines at the heart of implant machines. In the course of its 40 year development, the worldwide implanter industry has reached annual sales levels around 2B, installed thousands of dedicated machines and directly employs thousands of workers. It represents in all these measures, as much and possibly more than any other industrial application of particle accelerator technology. This presentation discusses the history of implanter development. It touches on some of the people involved and on some of the developmental changes and challenges imposed as the requirements of the semiconductor industry evolved.

MacKinnon, Barry A.; Ruffell, John P.

2011-06-01

104

Electronic Communications Technologies and the Transition to College: Links to Parent-Child Attachment and Adjustment  

ERIC Educational Resources Information Center

Electronic communications technologies (ECTs) help college students and parents remain in contact. Because recent reports have emphasized a link between ECTs, helicopter parenting, and autonomy issues, this study focused on the significance of contact patterns for attachment and student adjustment. First-semester college students (199 female, 81…

Sarigiani, Pamela A.; Trumbell, Jill M.; Camarena, Phame M.

2013-01-01

105

Information Technology for Workplace Communication. Workscape 21: The Ecology of New Ways of Working.  

ERIC Educational Resources Information Center

A study was undertaken to understand the role of electronic communication technologies (ECTs) in maintaining work-related communication. The study site was Sun Microsystems, a company at the high end of the curve in terms of its commitment to and employees' experience with ECTs. An electronic focus group (n=40, 4% response) and an e-mail survey…

Becker, Franklin; Tennessen, Carolyn M.; Young, David

106

Drainage of a nanocon ned simple uid: rate e ects on squeeze-out dynamics Lionel Bureau and Arnaud Arvengas  

E-print Network

Drainage of a nanocon#12;ned simple uid: rate e#11;ects on squeeze-out dynamics Lionel Bureau #3, 2008) We investigate the e#11;ect of loading rate on drainage in molecularly thin #12;lms of a simple addressed this question by performing, on a home-built SFA, drainage experiments at various veloc- ities

Recanati, Catherine

107

Speech Understanding with a New Implant Technology: A Comparative Study with a New Nonskin Penetrating Baha System  

PubMed Central

Objective. To compare hearing and speech understanding between a new, nonskin penetrating Baha system (Baha Attract) to the current Baha system using a skin-penetrating abutment. Methods. Hearing and speech understanding were measured in 16 experienced Baha users. The transmission path via the abutment was compared to a simulated Baha Attract transmission path by attaching the implantable magnet to the abutment and then by adding a sample of artificial skin and the external parts of the Baha Attract system. Four different measurements were performed: bone conduction thresholds directly through the sound processor (BC Direct), aided sound field thresholds, aided speech understanding in quiet, and aided speech understanding in noise. Results. The simulated Baha Attract transmission path introduced an attenuation starting from approximately 5?dB at 1000?Hz, increasing to 20–25?dB above 6000?Hz. However, aided sound field threshold shows smaller differences and aided speech understanding in quiet and in noise does not differ significantly between the two transmission paths. Conclusion. The Baha Attract system transmission path introduces predominately high frequency attenuation. This attenuation can be partially compensated by adequate fitting of the speech processor. No significant decrease in speech understanding in either quiet or in noise was found. PMID:25140314

Caversaccio, Marco

2014-01-01

108

Identifying technology spillovers and product market Nicholas Bloomy  

E-print Network

's position in technology space and product market space. Using panel data on U.S. ...rms we show theoretical research on product market rivalry e�ects of R&D (including patent race models), there has been

Sekhon, Jasjeet S.

109

ECT associated musical hallucinations in an elderly patient: a case report  

Microsoft Academic Search

Electro Convulsive Therapy (ECT) is a medical treatment for severe mental illness in which small, carefully controlled electricity is applied to the brain. This electric stimulation is done in conjunction with anesthesia and muscle relaxant medications to produce a mild generalized seizure. This is used to treat a variety of psychiatric disorders. This is most effective in the treatment of

Raguraman Janakiraman; Keith Wildgoose; Kalyan Seelam

2006-01-01

110

Coulomb interaction e ects on nonlinear optical response in C60, C70, and higher fullerenes  

E-print Network

Coulomb interaction e ects on nonlinear optical response in C60, C70, and higher fullerenes (Running head: Nonlinear optical response in higher fullerenes) Kikuo Harigaya Physical Science Division in the fullerene C60 and the extracted higher fullerenes { C70, C76, C78, and C84 { are theoretically investigated

Harigaya, Kikuo

111

A Marked Point Process Model for the Source Proximity E ect in the Indoor Environment 1  

E-print Network

. McBride Abstract In indoor air quality studies, discrepancies between personal and station- ary indoor air quality monitors arise because of the source proximity e#11;ect, in which pollutant sources KEY WORDS: Pulsed time series; Marked point process; Indoor air quality; Human exposure; Source

West, Mike

112

A Computational Study of the E4ect of Vasomotion on Oxygen Transport from Capillary Networks  

Microsoft Academic Search

The objective of this study was to investigate the e!ect of arteriolar vasomotion on oxygen transport from capillary networks. A computational model was used to calculate blood #ow and oxygen transport from a simulated network of striated muscle capillaries. For varying tissue oxygen consumption rates, the importance of the frequency and amplitude of vaso- motion-induced blood #ow oscillations was studied.

DANIEL GOLDMAN; ALEKSANDER S. POPEL

2001-01-01

113

Modeling Transport E ects on Ground-Level Ozone Using a  

E-print Network

Modeling Transport E ects on Ground-Level Ozone Using a Non-Stationary Space-Time Model Hsin on Ground-Level Ozone 1 #12;Summary This article presents a novel autoregressive space-time model for ground-level- temporal covariance structure of ground-level ozone by a separable spatio-temporal covariance function

Huang, Su-Yun

114

Mathematical Existence of Crystal Growth with GibbsThomson Curvature E#ects 1  

E-print Network

Mathematical Existence of Crystal Growth with Gibbs­Thomson Curvature E#ects 1 by Fred Almgren 2 one type of growth of a crystal as it freezes from a cold melt. The crystal freezes (melts) as rapidly. CHAPTER 2. Ingredients of our model of crystal growth. 2.1 The ambient space. 2.2 Crystals. 2.3 Heat

Wang, Lihe

115

Eff ects of Hydrodynamically Rough Grassed Waterways on Dissolved Reactive Phosphorus Loads Coming from Agricultural Watersheds  

Microsoft Academic Search

A modifi ed type of grassed waterway (GWW) with large hydrodynamic roughness has proven ability to reduce sediment load and surface runoff under conditions where best management practices on the delivering fi elds reduce sediment inputs that could otherwise damage the grass cover. It is unknown how such a GWW aff ects the loading of surface runoff with dissolved reactive

P. Fiener; K. Auerswald

116

The Application and E ect of Sampling Methods on Collecting Network Trac Statistics  

E-print Network

The Application and E#11;ect of Sampling Methods on Collecting Network Tra�c Statistics Kedar, jypang@cs.cmu.edu April 28, 2001 Abstract The relative performance of di#11;erent sampling methods the sampled data have compared to the original tra�c, which sampling method works best for a given tra

117

Initial Results from a Study of the E ects of Meditation on Multitasking Performance  

E-print Network

Initial Results from a Study of the E ects of Meditation on Multitasking Performance MEDITATION CONTROL MEDITATION RELAXATION 8 weeks 8 weeks memorytask performance/strategy None of the groups showed the meditation group demonstrated a major change in multi- tasking strategy, namely, a marked tendency to spend

Wobbrock, Jacob O.

118

ELEVENTH BOWDITCH LECTURE Eff ects of Distortion of Sensory Input on the Visual  

E-print Network

, and in sensory systems such as the somatic, auditory, and visual, where one can study the responses of neuronesELEVENTH BOWDITCH LECTURE Eff ects of Distortion of Sensory Input on the Visual System of Kittens. The most rapid progress has been made in the spinal cord where relatively simple reflexes can be isolated

Hubel, David

119

Top Ten Reasons a Graduate Student Should Apply to Be an ECT Foundation Intern  

ERIC Educational Resources Information Center

In this article, the author encourages graduate students to apply for the ECT Foundation Internship. She presents a list of the top ten benefits the internship offers a graduate student's career: (1) It could change your life. It changed mine; (2) Networking; (3) Mentoring; (4) Leadership opportunities; (5) Behind the scenes pass; (6) Shadowing;…

York, Cindy S.

2009-01-01

120

Microsoft Word - App 9-2 ECT Form Specs.doc  

Cancer.gov

Appendix 9-2 1 Lung Screening Study Version 3.0 Manual of Operations and Procedures 11/15/00 Lung Screening Study Specifications for Completion of the Record of Experience, Credentials and Training (ECT) (Examiner/Quality Assurance Examiner/Abstractor/Nosologist

121

The role of Atlantic ocean-atmosphere coupling in a ecting North Atlantic Oscillation variability  

E-print Network

The role of Atlantic ocean-atmosphere coupling in a#11;ecting North Atlantic Oscillation Atlantic ocean as a heat reservoir 10 3.1 The reduced thermal damping argument . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 4 The North Atlantic Ocean as a heat carrier 28 4.1 NAO / ocean circulation interaction

Huck, Thierry

122

Master's project in biology/immunology, 30 and 45 ECTS Exploring autoreactive B lymphocytes  

E-print Network

Master's project in biology/immunology, 30 and 45 ECTS Exploring autoreactive B lymphocytes Project of immunological techniques and equipment - Weekly lab meetings, journal clubs and seminars in immunology have a relevant background with completed courses in immunology and/or infectious biology. -Experience

Uppsala Universitet

123

UCHC Competency Checklist: ANNUAL Position Title: Registered Nurse, JDH Employee Name: ________________ Unit: ECT  

E-print Network

vs. PEC, Probable Cause Hearings, Patients Rights, Medication/ECT: Administration Without Patients and times all entries in the medical record Initiates patient care plan per patient diagnosis 1:1 Observation / Constant Observation Medications: Double Check Ostomy Care ­ protocol, teaching

Oliver, Douglas L.

124

Submitted on: July 11, 2002 Cosmological Recombination of Lithium and its E ect on the  

E-print Network

Submitted on: July 11, 2002 Cosmological Recombination of Lithium and its E#11;ect on the Microwave microwave background (CMB) mea- surements. For the popular set of cosmological parameters, about a #12;fth wavelengths around #24; 300 #22;m, as orig- inally suggested by Loeb (2001). The modi#12;ed anistropies

Stancil, Phillip C.

125

The E ect of Knowledge on Belief: Conditioning, Speci city and the Lottery  

E-print Network

The E ect of Knowledge on Belief: Conditioning, Speci city and the Lottery Paradox in Default version of the lottery paradox is given if we want to be able to say that individuals that are typical of the lottery paradox 19]. In the other case we have more speci c knowledge competing with more general

Poole, David

126

E ects of Monocular Deprivation and Reverse Suture On Orientation Maps Can Be Explained By  

E-print Network

E#11;ects of Monocular Deprivation and Reverse Suture On Orientation Maps Can Be Explained By Activity-Instructed Development of Geniculocortical Connections Kenneth D. Miller y and Ed Erwin #3; Depts Deprivation and Reverse Suture Text data: 34 text pages, 0 tables, 8 #12;gures. Address Correspondence To

Columbia University

127

Generalised boundary conditions for the Aharonov-Bohm e ect combined with  

E-print Network

, A = A hmf +AAB , with the part A hmf corresponding to the homogeneous magnetic #28;eld in the circular gauge, A hmf = {B 2 ( x 2 dx 1 + x 1 dx 2 ); and with the part AAB corresponding to the idealised AB e#27;ect

128

Multiple Dimensions of Balance are Adversely A ected in Older Adults with Fibromyalgia  

E-print Network

Multiple Dimensions of Balance are Adversely A ected in Older Adults with Fibromyalgia Table 1 this important question with a group of older adults with FM. The Fullerton Advanced Balance (FAB) Scale was originally designed to evaluate the multiple dimensions of balance in independently functioning older adults

de Lijser, Peter

129

E ects of Lithospheric Strength on Convection in the Earth's Mantle  

E-print Network

E ects of Lithospheric Strength on Convection in the Earth's Mantle by Clinton Phillips Conrad, dense, mantle lithosphere descends into the mantle interior, either through subduction for plate-scale ow, or as localized convective instability beneath lithospheric plates. The deformation associated

Conrad, Clint

130

Course title Teaching in Higher Education, step 1: Learning, Instructing and Knowledge, 6 ECTS  

E-print Network

Course title Teaching in Higher Education, step 1: Learning, Instructing and Knowledge, 6 ECTS Credits Course category Commission course Course code 799G24 Aim of the course On the successful completion of the course, course participants will be able to: - plan for and carry out teaching in the own

Zhao, Yuxiao

131

ccsd00000448 Swelling of phospholipid oating bilayers: the e ect of chain length  

E-print Network

ccsd­00000448 (version 1) : 26 Jun 2003 Swelling of phospholipid oating bilayers: the e#11;ect of a homogeneous lipid bilayer, oating near an identical bilayer deposited on the hydrophilic surface of a silicon, n, varying from 16 to 20. The average and r.m.s. positions of the oating bilayer were determined

132

Some Considerations of the Tolerability of Ketamine for ECT Anesthesia: A Case Series and Review of the Literature.  

PubMed

Most anesthetic agents used for electroconvulsive therapy (ECT) have few intrinsic adverse effects. Ketamine, however, is well known to be associated with a variety of adverse effects including nausea, dizziness, and psychotomimetic phenomena. Over the past several decades, there have been numerous reports on the use of ketamine for ECT anesthesia, with varied assessments on how prominent these adverse effects are in the ECT situation. Ketamine has received a resurgence of interest as an ECT anesthetic of late owing to its established independent antidepressant effects and to theoretical reasons why it might lessen the cognitive adverse effects of ECT. In this case series, the author reviews the experience with 14 patients who had undergone ECT who were switched to ketamine as anesthetic from methohexital at the preference of the treating anesthesiologist. All 14 patients spontaneously reported a strong preference not to be given ketamine again due to bothersome adverse effects. The latter consisted of either vestibular-type symptoms (nausea/vomiting, dizziness, and vertigo) or psychotomimetic effects (dissociative phenomena). It is concluded that ketamine is not free of adverse effects when used as an ECT anesthetic. Electroconvulsive therapy clinicians should be vigilant about assessing for these effects when ketamine is used, and consideration should be given to using a benzodiazepine such as diazepam or midazolam at seizure termination when ketamine anesthesia is used to prevent bothersome adverse effects seen upon awakening. PMID:24820945

Rasmussen, Keith G; Ritter, Matthew J

2014-12-01

133

Ion Implant  

NSDL National Science Digital Library

This website includes an animation which illustrates the ion implant process. Objective: Name the three common dopants used in implantation processes and explain the process of generating an ion beam from source to wafer. You can find this animation under the heading "Process & Equipment III." This simulation is from Module 026 of the Process & Equipment III Cluster of the MATEC Module Library (MML). To view other clusters or for more information about the MML visit http://matec.org/ps/library3/process_I.shtmlKey

2012-10-04

134

Science Highlights from the RBSP-ECT Particle Instrument Suite on NASA's Van Allen Probes Mission  

NASA Astrophysics Data System (ADS)

The NASA Van Allen Probes mission includes an instrument suite known as the Radiation Belt Storm Probes (RBSP) - Energetic Particle, Composition, and Thermal Plasma (ECT) suite. RBSP-ECT contains a well-proven complement of particle instruments to ensure the highest quality measurements ever made in the radiation belts and the inner magnetosphere. The coordinated RBSP-ECT particle measurements, analyzed in combination with fields and waves observations and state of-the-art theory and modeling, provide new understanding on the acceleration, global distribution, and variability of radiation belt electrons and ions, key science objectives of NASA's Living With a Star program and the Van Allen Probes mission. The RBSP-ECT suite consists of three highly-coordinated instruments: the Helium Oxygen Proton Electron (HOPE) spectrometer, the Magnetic Electron Ion Spectrometer (MagEIS), and the Relativistic Electron Proton Telescope (REPT). Collectively these three instrument types cover comprehensively the full electron and ion spectra from one eV to 10's of MeV with sufficient energy resolution, pitch angle coverage and resolution, and with composition measurements in the critical energy range up to 50 keV and also from a few to 50 MeV/nucleon. All three instruments are based on measurement techniques proven in the radiation belts, then optimized to provide unambiguous separation of ions and electrons and clean energy responses even in the presence of extreme penetrating background environments. In this presentation, we summarize overall ECT science goals and then show scientific results derived from the ECT suite on the dual Van Allen Probes spacecraft to date. Mission operations began only in late October 2012, and we have now achieved significant results. Results presented here will include substantial progress toward resolving primary Van Allen Probes science targets, such as: the relative role of localized acceleration versus transport-generated particle acceleration; the role of plasma electron temperature anisotropies, whistler waves, and radiation belt electron variability; global characteristics of outer zone electron drift loss to the magnetopause; the role of storms, substorms, and ion composition in radiation belt dynamics, both in terms of sources and sinks; new physical perspectives on inner zone and slot protons and electrons; and, how plasmasphere properties control or influence radiation belt behavior.

Spence, Harlan

2014-05-01

135

Sub-2y node NAND flash characteristics using spot beam technology for low energy, high tilt implant for n-poly doping  

NASA Astrophysics Data System (ADS)

Reduction of polysilicon sheet resistivity and polysilicon depletion ratio (PDR) are two major challenges for improving the memory cell characteristics of sub-20 nm NAND Flash devices. High phosphorus doses are implanted into in situ doped polysilicon floating gates to improve PDR, but phosphorus concentrations that are too high can degrade cell characteristics by increasing trapped charge in the TNOX(Tunnel Oxide). It is also important to prevent the bending of narrow polysilicon lines during floating gate implantation. We explored various conditions of low energy, high tilt phosphorus implants for floating gate doping using a spot beam high current implanter. The optimal concentration of implant energy, tilt angle, and thermal annealing has been shown to improve PDR and floating gate TOP CD control.

Ryu, Chong-Il; Lee, Sangsun; Jeon, Young-Ho; Cheon, Youngil; Choi, Jin-Kwan; Yang, Young-Ho; Lee, Kyung-Won; Hong, Rympyo; Yoon, Jong-Yoon; Reece, Ron; Rubin, Leonard M.

2012-11-01

136

The effects of ECT stimulus dose and electrode placement on the ictal electroencephalogram: an intraindividual crossover study.  

PubMed

Recent evidence suggests that electroconvulsive therapy (ECT) efficacy depends upon both electrode placement and the degree to which stimulus dosage exceeds seizure threshold (T), and not simply on surpassing a minimum seizure duration as has been assumed. In light of these findings and studies reporting ictal electroencephalogram (EEG) differences between bilateral and unilateral ECT, we performed this 19-subject intraindividual crossover study of the effects of dose and electrode placement on the ictal EEG. We found ictal EEG evidence of greater seizure intensity with bilateral than unilateral ECT and with higher dosage (2.25 T) compared with barely suprathreshold stimuli. Seizure duration was not longer with bilateral than unilateral ECT and actually decreased with increased dose. A number of ictal EEG variables separated the unilateral 2.25 T and unilateral T conditions, which reportedly differ in efficacy, and therefore, these EEG measures show promise as markers of treatment adequacy. PMID:8292679

Krystal, A D; Weiner, R D; McCall, W V; Shelp, F E; Arias, R; Smith, P

1993-12-01

137

How robust is the evidence on the e ects of college quality? Evidence from matching  

Microsoft Academic Search

We estimate the e ects of college quality using propensity score matching methods and the National Longitudinal Survey of Youth 1979 cohort. Matching allows us to relax the linear functional form assumption implicit in regression-based estimates. We also examine the support problem by determining whether there are individuals attending low-quality colleges similar to those attending high-quality colleges, and 4nd that

Dan A. Blacka; A. Smith

2004-01-01

138

Long-range memory and non-Markov statistical e%ects in human sensorimotor coordination  

Microsoft Academic Search

Abstract In this paper, the non-Markov statistical processes and long-range memory e%ects in human sensorimotor coordination are investigated. The theoretical basis of this study is the statistical theory of non-stationary discrete non-Markov processes in complex systems (Phys. Rev. E 62, 6178 (2000)). The human,sensorimotor coordination was experimentally studied by means of standard dynamical tappingtest on the g roup of 32

Renat M. Yulmetyev; Natalya Emelyanova; Peter H-anggi; Fail Gafarov; Alexander Prokhorov

139

ccsd00000821 Alloy e ects in Ga 1 x In x N=GaN heterostructures  

E-print Network

ccsd­00000821 (version 1) : 6 Nov 2003 Alloy e#11;ects in Ga 1 x In x N=GaN heterostructures Duc, 75005 Paris, France We show that the large band o#11;sets between GaN and InN and the heavy carrier e#11 structure of Ga1 xInxN=GaN heterostructures while this approximation works very well for the Ga1 xInxAs=Ga

140

Efficacy of 67 gallium ECT imaging in lymphoma, infection, and lung carcinoma: A comparison with planar imaging  

SciTech Connect

Emission computed tomography (ECT) studies were performed on a GE 400 A/T camera and ADAC computers (system 3 and system 3300). Thirty-three sets of ECT and planar images were obtained in 20 patients over a six month period. Imaging was performed 48 hours after the intravenous administration of 5 mc of Gallium 67 citrate. No bowel preparation was employed. Comparison is made of the initial nuclear medicine report derived from planar and ECT imaging aided by clinical knowledge versus the consensus opinion of two nuclear medicine physicians reading the planar images along with minimal clinical information. The lymphoma series consists of 18 scans in 10 patients. There were 5 scans in which a false negative planar interpretation was changed to a true positive ECT interpretation. Sensitivity of planar imaging for lymphoma was 58% which rose to 100% with addition of ECT information. There were no false positives by either technique. There were 5 sets of scans in 5 lung carcinoma patients. Sensitivity of the planar images was 60% because of 2 false negative results. Sensitivity of the ECT technique was 100%. There were no false positives. The infection series consists of 10 scans in 5 patients. Sensitivity of ECT was 100%, sensitivity of planar was 66%. There was 1 false positive planar. For the total series the accuracy of planar imaging was 69% and the predictive value of a negative planar interpretation was 44%. Corresponding values for ECT imaging were 100%. The authors' experience demonstrates significant increase in sensitivity without loss of specificity resulting from the use of Emission Computed Tomography in both chest and abdomen in patients with lymphoma, infection, and lung cancer.

Harwood, S.J.; Anderson, M.W.; Klein, R.C.; Friedman, B.I.; Carroll, R.G.

1984-01-01

141

ECT Evaluation by an Error Measurement System According to IEC 60044-8 and 61850-9-2  

Microsoft Academic Search

A high-accuracy error measurement system for calibration of digital-output equipped electronic current transformers (ECTs) is described. The system has been developed in conformity with the requirements for digital information networks in IEC 61850-9-2 and for accuracy class and error measurement procedures in IEC 60044-8. The system has also been designed to achieve simultaneous and synchronous samplings between an ECT\\/MU and

Tatsuji Yamada; Saytaro Kon; Naoki Hashimoto; Tatsushi Yamaguchi; Kenichi Yazawa; Reishi Kondo; Kiyoshi Kurosawa

2012-01-01

142

EEL 5322 VLSI CIRCUITS AND TECHNOLOGY SYLLABUS Course Outline: (See Course Video Lectures Tab for Streaming Videos and Video Downloads)  

E-print Network

and Permission Form, Class 2 Notes CMOS Technology, Gaussian Analysis Handout Statistics Web References, Implant Concept Graphics, Ion Implant Web references, Class Notes 3 Ion Implantation, Ion Implant Range Tables) Lecture 4 - Ion Implantation Notes Additional Implant Graphics, Implant Example Problems, Implant patent

Fang, Yuguang "Michael"

143

Contraceptive Implants  

Microsoft Academic Search

Subdermal contraceptive implants offer women long-acting, controlled release of progestins. Over the past 20 years, they have\\u000a been approved in more than 60 countries and used by more than 11 million women worldwide. Their high efficacy along with ease\\u000a of use make them a good contraceptive option for women who require progestin-only methods because they should not use estrogen,\\u000a teens

Philip D. Darney

144

Implant radiography and radiology.  

PubMed

The practitioner placing dental implants has many options with respect to pre-implant radiographic assessment of the jaws. The advantages and disadvantages of the imaging modalities currently available for pre-implant imaging are discussed in some detail. Intra-oral and extra-oral radiographs are generally low dose but the information provided is limited as the images are not three-dimensional. Tomography is three-dimensional, but the image quality is highly variable. Computed tomography (CT) has been the gold standard for many years as the information provided is three-dimensional and generally very accurate. However, CT examinations are expensive and deliver a relatively high radiation dose to the patient. The latest imaging modality introduced is cone beam volumetric tomography (CBVT) and this technology is very promising with regard to pre-implant imaging. CBVT generally delivers a lower dose to the patient than CT and provides reasonably sharp images with three-dimensional information. A comparison between CT and CBVT is provided. Magnetic resonance imaging is showing some promise, but the examinations are not readily available, generally expensive and bone is not well imaged. Magnetic resonance imaging is excellent for demonstrating soft tissues and therefore may be of great use in identifying the inferior dental nerve and vessels. All of the above technology is of little value if the information required is not obtained and so information is also provided on imaging of some of the vital structures. Of particular interest is the inferior dental canal, incisive canals of the mandible, genial foramina and canals, maxillary sinus and the incisive canal and foramen of the maxilla. PMID:18498579

Monsour, P A; Dudhia, R

2008-06-01

145

A novel strategy for long-term implantable artificial pancreas  

Microsoft Academic Search

Technology has recently changed type 1 diabetes treatment by introducing several advancements able to improve patients' quality of life. However, despite of several decades of research efforts, the dream of a fully-automated implanted artificial pancreas is quite far from its realization. The need for periodically restoring the implanted battery charge and refilling the implanted insulin reservoir are the main issues,

Leonardo Ricotti; Tareq Assaf; Arianna Menciassi; Paolo Dario

2011-01-01

146

Photobiomodulation and implants: implications for dentistry  

PubMed Central

The use of dental implants has become a mainstay of rehabilitative and restorative dentistry. With an impressive clinical success rate, there remain a few minor clinical issues with the use of implants such as peri-implant mucositis and peri-implantitis. The use of laser technology with implants has a fascinating breadth of applications, beginning from their precision manufacturing to clinical uses for surgical site preparation, reducing pain and inflammation, and promoting osseointegration and tissue regeneration. This latter aspect is the focus of this review, which outlines various studies of implants and laser therapy in animal models. The use of low level light therapy or photobiomodulation has demonstrated its efficacy in these studies. Besides more research studies to understand its molecular mechanisms, significant efforts are needed to standardize the clinical dosing and delivery protocols for laser therapy to ensure the maximal efficacy and safety of this potent clinical tool for photobiomodulation. PMID:24455438

Tang, Elieza

2013-01-01

147

Nanostructured Surfaces of Dental Implants  

PubMed Central

The structural and functional fusion of the surface of the dental implant with the surrounding bone (osseointegration) is crucial for the short and long term outcome of the device. In recent years, the enhancement of bone formation at the bone-implant interface has been achieved through the modulation of osteoblasts adhesion and spreading, induced by structural modifications of the implant surface, particularly at the nanoscale level. In this context, traditional chemical and physical processes find new applications to achieve the best dental implant technology. This review provides an overview of the most common manufacture techniques and the related cells-surface interactions and modulation. A Medline and a hand search were conducted to identify studies concerning nanostructuration of implant surface and their related biological interaction. In this paper, we stressed the importance of the modifications on dental implant surfaces at the nanometric level. Nowadays, there is still little evidence of the long-term benefits of nanofeatures, as the promising results achieved in vitro and in animals have still to be confirmed in humans. However, the increasing interest in nanotechnology is undoubted and more research is going to be published in the coming years. PMID:23344062

Bressan, Eriberto; Sbricoli, Luca; Guazzo, Riccardo; Tocco, Ilaria; Roman, Marco; Vindigni, Vincenzo; Stellini, Edoardo; Gardin, Chiara; Ferroni, Letizia; Sivolella, Stefano; Zavan, Barbara

2013-01-01

148

Appraisal of evidence base for introduction of new implants in hip and knee replacement: a systematic review of five widely used device technologies  

PubMed Central

Objective To determine the evidence of effectiveness and safety for introduction of five recent and ostensibly high value implantable devices in major joint replacement to illustrate the need for change and inform guidance on evidence based introduction of new implants into healthcare. Design Systematic review of clinical trials, comparative observational studies, and registries for comparative effectiveness and safety of five implantable device innovations. Data sources PubMed (Medline), Embase, Web of Science, Cochrane, CINAHL, reference lists of articles, annual reports of major registries, summaries of safety and effectiveness for pre-market application and mandated post-market studies at the US Food and Drug Administration. Study selection The five selected innovations comprised three in total hip replacement (ceramic-on-ceramic bearings, modular femoral necks, and uncemented monoblock cups) and two in total knee replacement (high flexion knee replacement and gender specific knee replacement). All clinical studies of primary total hip or knee replacement for symptomatic osteoarthritis in adults that compared at least one of the clinical outcomes of interest (patient centred outcomes or complications, or both) in the new implant group and control implant group were considered. Data searching, abstraction, and analysis were independently performed and confirmed by at least two authors. Quantitative data syntheses were performed when feasible. Results After assessment of 10?557 search hits, 118 studies (94 unique study cohorts) met the inclusion criteria and reported data related to 15?384 implants in 13?164 patients. Comparative evidence per device innovation varied from four low to moderate quality retrospective studies (modular femoral necks) to 56 studies of varying quality including seven high quality (randomised) studies (high flexion knee replacement). None of the five device innovations was found to improve functional or patient reported outcomes. National registries reported two to 12 year follow-up for revision occurrence related to more than 200?000 of these implants. Reported comparative data with well established alternative devices (over 1?200?000 implants) did not show improved device survival. Moreover, we found higher revision occurrence associated with modular femoral necks (hazard ratio 1.9) and ceramic-on-ceramic bearings (hazard ratio 1.0-1.6) in hip replacement and with high flexion knee implants (hazard ratio 1.0-1.8). Conclusion We did not find convincing high quality evidence supporting the use of five substantial, well known, and already implemented device innovations in orthopaedics. Moreover, existing devices may be safer to use in total hip or knee replacement. Improved regulation and professional society oversight are necessary to prevent patients from being further exposed to these and future innovations introduced without proper evidence of improved clinical efficacy and safety. PMID:25208953

Nieuwenhuijse, Marc J; Nelissen, R G H H; Schoones, J W

2014-01-01

149

Use of digital data acquisition and CAD/CAM technology for the fabrication of a fixed complete dental prosthesis on dental implants.  

PubMed

The work flow in this report describes a metal-resin fixed complete dental prosthesis fabricated by using digital data acquisition at the implant fixture level with a computer-aided design and computer-aided manufacturing (CAD/CAM) fabricated tissue-colored anodized titanium framework. PMID:24189115

Lin, Wei-Shao; Harris, Bryan T; Zandinejad, Amirali; Morton, Dean

2014-01-01

150

[Comperative study of implant surface characteristics].  

PubMed

The osseointegration between the implant and its' bone environment is very important. The implants shall meet the following requirements: biocompatibility, rigidity, resistance against corrosion and technical producibility. In our present study surface morphology and material characteristics of different implants (Denti Bone Level, Denti Zirconium C, Bionika CorticaL, Straumann SLA, Straumann SLA Active, Dentsply Ankylos and Biotech Kontact implant) were investigated with scanning electron microscopy and energy-dispersive X-ray spectroscopy. The possible surface alterations caused by the manufacturing technology were also investigated. During grit-blasting the implants' surface is blasted with hard ceramic particles (titanium oxide, alumina, calcium phosphate). Properties of blasting material are critical because the osseointegration of dental implants should not be hampered. The physical and chemical features of blasting particles could importantly affect the produced surfaces of implants. Titanium surfaces with micro pits are created after immersion in mixtures of strong acids. On surfaces after dual acid-etching procedures the crosslinking between fibrin and osteogenetic cells could be enhanced therefore bone formation could be directly facilitated on the surface of the implant. Nowadays there are a number of surface modification techniques available. These can be used as a single method or in combination with each other. The effect of the two most commonly used surface modifications (acid-etching and grit-blasting) on different implants are demonstrated in our investigation. PMID:24551957

Katona, Bernadett; Daróczi, Lajos; Jenei, Attila; Bakó, József; Hegedus, Csaba

2013-12-01

151

Histories of cochlear implantation.  

PubMed

The cochlear implant, an electronic device by means of which some totally deaf people can be provided with a form of hearing, has been increasingly used since the early 1980s. The mass media have typically presented it as an example of the remarkable success of modern technological medicine. In France and The Netherlands, the countries on which this paper focuses, as in many others, deaf communities have rejected the technology. They have protested at its use with deaf children in particular. Rather than locating it in a history of medical progress, they have located it within a history of their own oppression. Each historical rendering is used to try to influence policy. The contest, however, is an unequal one. PMID:10501645

Blume, S S

1999-11-01

152

Neural networks in electrical capacitance tomography (ECT)-based interface detection  

NASA Astrophysics Data System (ADS)

Tomographic systems have been tested in separators for estimating the distribution of the three phases (including emulsion and foam) via interface detection in various laboratories. Experiments and simulations show that electrical capacitance tomography (ECT) is capable of detecting the interface accurately in spite of the high conductivity of the water present. Due to the high conductivity of the water/brine in the pipe separator, the sensitivity of the capacitance measurements is to a certain extent immune to variations in material properties. In a series of preliminary tests, capacitance tomography was used to estimate the interface in a pipe separator containing oil and water/brine. Results obtained from laboratory scale models are presented and discussed with some information on the uncertainties involved. Artificial neural networks exhibit enhanced ability to mask variations in unwanted/unimportant parameters in the separation process, thus reducing the complexities involved in the solution of the essentially underdetermined system of equations evolving out of different models developed for the system. Due to ample data being available from tomographic systems, a data driven soft sensor (virtual sensor) approach is also discussed with some considerations on processing times to address the potential of the ECT in real time measurement and control applications.

Ru, Yan; Pradeep, Chaminda; Mylvaganam, Saba

2011-10-01

153

Missing Women and the Price of Tea in China: The E ff ect of Relative Female Income on Sex Imbalance (Job Market Paper)  

Microsoft Academic Search

Economists have long argued that the severe sex imbalance which ex- ists in many developing countries is caused by underlying economic con- ditions. However, observed association between sex ratios and economic conditions may not re fl ect their true e ff ect to the extent sex ratios and economic conditions are associated with omitted variables such as sex preferences. This

154

Proc. of the 5 th Int. Conference on Digital Audio E#ects (DAFx02), Hamburg, Germany, September 2628, 2002 DOPPLER SIMULATION AND THE LESLIE  

E-print Network

­28, 2002 DOPPLER SIMULATION AND THE LESLIE Julius Smith, Stefania Serafin Center for Computer Research to achieve the Leslie e#ect. Measurements of a horn from a real Leslie are used to calibrate angle of the ``Leslie e#ect.'' The Leslie is a popular audio processor used with elec­ tronic organs and other

Smith III, Julius Orion

155

Comparison between the effect of liothyronine and piracetam on personal information, orientation and mental control in patients under treatment with ECT  

PubMed Central

Objective: The study aimed to compare the effect of liothyronine and piracetam on three subscales of the Wechsler memory test on patients under treatment with ECT. Materials and Methods: In a double blind clinical trial, 60 of 99 patients between 20 and 45 years old, under treatment with ECT were studied in three groups. Patients in the allocation groups received liothyronine, piracetam, or placebo, from the first session of ECT until 1 month after the last session of ECT. Personal information, orientation, and mental control were tested in the participants at first, fourth, and last session of ECT and 1 month after the last session of ECT. Data were analyzed with Repeated measure ANOVA using SPSS 13. Results: There wasn’t any significant difference among three groups in demographic characteristics before the study and number of ECT sessions (P=0.684). After intervention, a significant difference in memory scores was seen in third and fourth assessment sessions (0.002). Orientation subscales showed a significant difference among four assessment sessions (P=0.001). Personal information and mental control never decreased in the liothyronine group. There was no significant difference among three studied groups in personal information, orientation, and mental control (P>0.05). Conclusion: Memory changes due to ECT may be limited to some parts of memory like orientation. More powerful studies for comparison between the effect of liothyronine and placebo are necessary. PMID:22988323

Ghafur, Mousavi Seyed; Saadat, Mohammad; Maraci, Mohamad Reza; Bagherian, Reza S.; Mazaheri, Mina

2012-01-01

156

30 GHz monolithic balanced mixers using an ion-implanted FET-compatible 3-inch GaAs wafer process technology  

NASA Technical Reports Server (NTRS)

An all ion-implanted Schottky barrier mixer diode which has a cutoff frequency greater than 1000 GHz has been developed. This new device is planar and FET-compatible and employs a projection lithography 3-inch wafer process. A Ka-band monolithic balanced mixer based on this device has been designed, fabricated and tested. A conversion loss of 8 dB has been measured with a LO drive of 10 dBm at 30 GHz.

Bauhahn, P.; Contolatis, A.; Sokolov, V.; Chao, C.

1986-01-01

157

Implant success!!!.....simplified.  

PubMed

The endeavor towards life-like restoration has helped nurture new vistas in the art and science of implant dentistry. The protocol of "restoration-driven implant placement" ensures that the implant is an apical extension of the ideal future restoration and not the opposite. Meticulous pre-implant evaluation of soft and hard tissues, diagnostic cast and use of aesthetic wax-up and radiographic template combined with surgical template can simplify the intricate roadmap for appropriate implant treatment.By applying the harmony of artistic skill, scientific knowledge and clinical expertise, we can simply master the outstanding implant success in requisites of aesthetics, phonetics and function. PMID:20376237

Luthra, Kaushal K

2009-01-01

158

Norplant implants.  

PubMed

This letter to the editor is in response to 3 articles on the use of the Norplant implant contraceptive in The Indian Health Service (IHS) Provider. Norplant and the FDA-approved Depo-Provera now expand contraceptive options for women. All IHS and 638 sites might be able to offer both options. Several of the authors expressed concern regarding decreased Norplant effectiveness in heavier patients. Norplant is still more effective than any other currently available reversible contraceptive in the US at all weights. Many experts feel the current silastic capsule provides adequate hormone levels even in heavier women. The Crow Service Unit has initiated their Norplant program, although the Wyeth consent form seems unnecessarily extensive. The Albuquerque Service Unit consent form simply describes the procedure and confirms that patients have read and understand the fact sheet. The theoretical risk of thromboembolism is vastly outweighed by the potential benefit of reliable contraception in high risk alcoholic women, except perhaps in women with severe liver disease. While Norplant is expensive, programs need to consider the actual cost of a pregnancy, potential complications, and the financial and social costs of unintended pregnancy. For those in difficult straits, the manufacturer has set up a foundation for obtaining Norplant free of charge. Depo-Provera comes in a 150 mg dose vial that is given every 3 months. The mean time to ovulation is 4.5 months from the last dose. The adverse reaction spectrum is similar to Norplant as they are both progesterone-related agents. Providers and clinics should reduce barriers to family planning by giving out more pill packs at a time; letting adolescents who wish to delay their first pelvic exam have 3 months of pills without an exam; making condoms available in exam rooms rather than through pharmacy prescriptions; and increasing patient accessibility to the morning-after pill. PMID:12288838

Henley, E

1993-06-01

159

Antidepressant efficacy of Sudarshan Kriya Yoga (SKY) in melancholia: a randomized comparison with electroconvulsive therapy (ECT) and imipramine  

Microsoft Academic Search

Background: Sudarshan Kriya Yoga (SKY) is a procedure that involves essentially rhythmic hyperventilation at different rates of breathing. The antidepressant efficacy of SKY was demonstrated in dysthymia in a prospective, open clinical trial. This study compared the relative antidepressant efficacy of SKY in melancholia with two of the current standard treatments, electroconvulsive therapy (ECT) and imipramine (IMN). Methods: Consenting, untreated

N. Janakiramaiah; B. N. Gangadhar; P. J. Naga Venkatesha Murthy; M. G. Harish; D. K. Subbakrishna; A. Vedamurthachar

2000-01-01

160

Continental Shelf Research 20 (2000) 1}13 Internal tide e!ects on a sewage plume  

E-print Network

Continental Shelf Research 20 (2000) 1}13 Internal tide e!ects on a sewage plume at Sand Island.A. Petrenko et al. / Continental Shelf Research 20 (2000) 1}13 #12;1.1. Circulation Circulation in Mamala Bay. Mooring D2 and the Sand Island sewage outfall are in bold. Cross-shelf sections 1}5 correspond

Fabrikant, Sara Irina

161

DATE : NVLAP LAB CODE: ECT INSTRUCTIONS FOR RENEWAL APPLICATIONS (2009-10-06) PAGE 1 OF 1  

E-print Network

DATE : NVLAP LAB CODE: ECT INSTRUCTIONS FOR RENEWAL APPLICATIONS (2009-10-06) PAGE 1 OF 1 will be reduced. Please list by NVLAP test method code (12/xxx) the test methods to be removed from the scope to Expand or Reduce Scope" file. d. Complete this form. The NVLAP test method codes can be found

162

Cusp formation for evolving bubbles in 2-D Stokes ow: the e ect of variable surface tension  

E-print Network

Cusp formation for evolving bubbles in 2-D Stokes ow: the e ect of variable surface tension Michael by the presence of surfactant, on a bubble evolving in 2-D Stokes ow. The evolution is driven by an exten- sional. The steady solutions include those for which the bubble is covered in a nonzero concentration of surfactant

Siegel, Michael

163

Monte Carlo Study of the E ects of Design Parameters on the Sensitivity of a CMB Polarization Experiment  

E-print Network

Monte Carlo Study of the E#11;ects of Design Parameters on the Sensitivity of a CMB Polarization a monte carlo to simulate Cosmic Microwave Background polarization maps on caps around the North Celestial Pole. We used this monte carlo to explore how the sensitivity of a single parameter #12;t depends

164

ePUB: Modellierung Molecular Life Sciences Master Major 90 ECTS-Credits with special qualification in Biochemistry/  

E-print Network

in Biochemistry/ Chemical Biology [Reglement 01.10.2005] Seite 1 1. Teil: Struktur des Studiums (Prüfungsfächer) Offizieller Abschluss: Master of Science in Molecular Life Sciences with special qualification in Biochemistry/Chemical Biology, Universität Bern ePUB - interne Bezeichnung: MLS M Major 90 ECTS Biochemistry/Chemical Biology

Richner, Heinz

165

Natural and Engineered Hydroxyectoine Production Based on the Pseudomonas stutzeri ectABCD-ask Gene Cluster? †  

PubMed Central

We report on the presence of a functional hydroxyectoine biosynthesis gene cluster, ectABCD-ask, in Pseudomonas stutzeri DSM5190T and evaluate the suitability of P. stutzeri DSM5190T for hydroxyectoine production. Furthermore, we present information on heterologous de novo production of the compatible solute hydroxyectoine in Escherichia coli. In this host, the P. stutzeri gene cluster remained under the control of its salt-induced native promoters. We also noted the absence of trehalose when hydroxyectoine genes were expressed, as well as a remarkable inhibitory effect of externally applied betaine on hydroxyectoine synthesis. The specific heterologous production rate in E. coli under the conditions employed exceeded that of the natural producer Pseudomonas stutzeri and, for the first time, enabled effective hydroxyectoine production at low salinity (2%), with the added advantage of simple product processing due to the absence of other cosolutes. PMID:21169432

Seip, Britta; Galinski, Erwin A.; Kurz, Matthias

2011-01-01

166

Technology.  

ERIC Educational Resources Information Center

Discussion of technology focuses on instructional technology. Topics include inquiry and technology; curriculum development; reflection and curriculum evaluation; criteria for technological innovations that will increase student motivation; standards; impact of new technologies on library media centers; software; and future trends. (LRW)

Callison, Daniel

2002-01-01

167

Osseointegrated implant failures.  

PubMed

This article discusses the criteria used for implant success and failure, the classification of implant failures, the causative factors, and diagnosis of the failing and failed implant. In spite of the impressive success rates of osseointegrated dental implants, failures occur and in some studies the incidence of failure is high. Many studies do not use objective criteria to define success and confuse survival with success. The criteria used affect reported success rates. Implant failures may occur early (primary) after implant placement or after the implant is loaded (secondary). There is no single aetiological factor and failures have been attributed to poor surgical technique, host factors that impair healing, poor bone quality, peri-implant infections, poor prosthesis design and traumatic loading conditions. Early diagnosis of problems is critical and every effort should be made to treat the problem while the damage can still be managed or even reversed. PMID:10686922

O'Mahony, A; Spencer, P

1999-01-01

168

Urinary incontinence - injectable implant  

MedlinePLUS

Injectable implants are injections of material into the urethra to help control urine leakage ( urinary incontinence ) caused by a ... into the tissue next to the sphincter. The implant procedure is usually done in the hospital. Or ...

169

A no bleed implant  

Microsoft Academic Search

Breast implants have evolved from the original saline-filled, smooth-surfaced silicone rubber bag to silicone gel-filled smooth-walled sacs to a combination of a silicone gel-filled bag within a saline-filled sac, and, most recently, a reversed, double-lumen implant with a saline bag inside of a gel-filled bag. Texture-surfaced implants were first used in 1970 when the standard silicone gelfilled implant was covered

Robert A. Ersek; Jose Alberto Navarro; Dora Zsofia Nemeth; George Sas

1993-01-01

170

CAD/CAM guided surgery in implant dentistry: a brief review.  

PubMed

Advanced imaging and CAD/CAM technologies and their applications in enhancing treatment outcomes in implant dentistry have gained widespread interest. Guided implant surgery utilizing these advanced technologies has significant applications in implant dentistry. This article provides information on some of the perceived advantages and disadvantages for planning guided versus conventional implant surgery as well as basic steps involved in the fabrication of guided surgical templates (GST). PMID:24881444

Kattadiyil, Mathew T; Parciak, Ewa; Puri, Shweta; Scherer, Michael D

2014-01-01

171

Physical understanding of cryogenic implant benefits for electrical junction stability  

SciTech Connect

We investigate the effect of cryogenic temperature implants on electrical junction stability for ultra shallow junction applications for sub-32 nm technology nodes and beyond. A comprehensive study was conducted to gain physical understanding of the impact of cryogenic temperature implants on dopant-defect interactions. Carborane (C{sub 2}B{sub 10}H{sub 12}) molecule, a potential alternative to monomer boron was implanted in carbon preamorphized silicon substrates at cryogenic implant temperatures. Results indicate implants at cryogenic temperatures increase dopant activation with reduced diffusion, resulting in lower sheet resistance for a lower junction depth. Further, this study emphasizes the benefits of co-implants performed at cryogenic temperatures as alternative to traditional preamorphizing implants.

Adeni Khaja, Fareen; Colombeau, Benjamin; Thanigaivelan, Thirumal; Ramappa, Deepak; Henry, Todd [Applied Materials-Varian Semiconductor Equipment, 35 Dory Road, Gloucester, Massachusetts 01930 (United States)

2012-03-12

172

Current Internet Technology and Statistics | Blessing or Curse? Jurgen Symanzik  

E-print Network

Current Internet Technology and Statistics | Blessing or Curse? Jurgen Symanzik George Mason overview on the history of the Internet and some of its main features. In the second part, we introduce exist- ingInternet technology that e ects todays education and research in Statistics. Examples

Symanzik, Jürgen

173

Middle Ear Implantable Hearing Devices: An Overview  

PubMed Central

Hearing loss affects approximately 30 million people in the United States. It has been estimated that only approximately 20% of people with hearing loss significant enough to warrant amplification actually seek assistance for amplification. A significant interest in middle ear implants has emerged over the years to facilitate patients who are noncompliant with conventional hearing aides, do not receive significant benefit from conventional aides, or are not candidates for cochlear implants. From the initial studies in the 1930s, the technology has greatly evolved over the years with a wide array of devices and mechanisms employed in the development of implantable middle ear hearing devices. Currently, these devices are generally available in two broad categories: partially or totally implantable using either piezoelectric or electromagnetic systems. The authors present an up-to-date overview of the major implantable middle ear devices. Although the current devices are largely in their infancy, indications for middle ear implants are ever evolving as promising studies show good results. The totally implantable devices provide the user freedom from the social and practical difficulties of using conventional amplification. PMID:19762429

Haynes, David S.; Young, Jadrien A.; Wanna, George B.; Glasscock, Michael E.

2009-01-01

174

Trends in Cochlear Implants  

PubMed Central

More than 60,000 people worldwide use cochlear implants as a means to restore functional hearing. Although individual performance variability is still high, an average implant user can talk on the phone in a quiet environment. Cochlear-implant research has also matured as a field, as evidenced by the exponential growth in both the patient population and scientific publication. The present report examines current issues related to audiologic, clinical, engineering, anatomic, and physiologic aspects of cochlear implants, focusing on their psychophysical, speech, music, and cognitive performance. This report also forecasts clinical and research trends related to presurgical evaluation, fitting protocols, signal processing, and postsurgical rehabilitation in cochlear implants. Finally, a future landscape in amplification is presented that requires a unique, yet complementary, contribution from hearing aids, middle ear implants, and cochlear implants to achieve a total solution to the entire spectrum of hearing loss treatment and management. PMID:15247993

Zeng, Fan-Gang

2004-01-01

175

Peri-implant soft tissue management: Where are we?  

PubMed

Dental implants have evolved dramatically over the last decade, and so have our expectations from them in terms of functional and esthetic criteria. The maintenance and augmentation of the soft tissue has emerged as an area of concern and focus. The triad of anatomical peri-implant characteristics, soft tissue response to the implant material, and clinical skill form the fundamental principles in augmenting soft tissue. However, as clinicians, where are we with regards to the ability to augment and maintain soft tissue around dental implants, about 40 years after the first implants were placed? We now understand that peri-implant soft tissue management begins with extraction management. Our treatment modalities have evolved from socket compression post-extraction, to socket preservation with an aim to enhance the eventual peri-implant soft tissue. This short communication will assess the evolution of our thought regarding peri-implant soft tissue management, augmentation of keratinized mucosa around implants, and also look at some recent techniques including the rotated pedicle connective tissue graft for enhancing inter-implant papilla architecture. With newer research modalities, such as cyto-detachment technology, and cutting-edge bioengineering solutions (possibly a soft-tissue-implant construct) which might be available in the near future for enhancing soft tissue, we are certainly in an exciting era in dentistry. PMID:23493178

Bhatavadekar, Neel

2012-10-01

176

Miniaturized neural interfaces and implants  

NASA Astrophysics Data System (ADS)

Neural prostheses are technical systems that interface nerves to treat the symptoms of neurological diseases and to restore sensory of motor functions of the body. Success stories have been written with the cochlear implant to restore hearing, with spinal cord stimulators to treat chronic pain as well as urge incontinence, and with deep brain stimulators in patients suffering from Parkinson's disease. Highly complex neural implants for novel medical applications can be miniaturized either by means of precision mechanics technologies using known and established materials for electrodes, cables, and hermetic packages or by applying microsystems technologies. Examples for both approaches will be introduced and discussed. Electrode arrays for recording of electrocorticograms during presurgical epilepsy diagnosis have been manufactured using approved materials and a marking laser to achieve an integration density that is adequate in the context of brain machine interfaces, e.g. on the motor cortex. Microtechnologies have to be used for further miniaturization to develop polymer-based flexible and light weighted electrode arrays to interface the peripheral and central nervous system. Polyimide as substrate and insulation material will be discussed as well as several application examples for nerve interfaces like cuffs, filament like electrodes and large arrays for subdural implantation.

Stieglitz, Thomas; Boretius, Tim; Ordonez, Juan; Hassler, Christina; Henle, Christian; Meier, Wolfgang; Plachta, Dennis T. T.; Schuettler, Martin

2012-03-01

177

Long-Term Modeling of Solar Energy: Analysis of Concentrating Solar Power (CSP) and PV Technologies  

Microsoft Academic Search

This report presents an overview of research conducted on solar energy technologies and their implementation in the ObjECTS framework. The topics covered include financing assumptions and selected issues related to the integration of concentrating thermal solar power (CSP) and photovoltaics PV technologies into the electric grid. A review of methodologies for calculating the levelized energy cost of capital-intensive technologies is

Yabei Zhang; Steven J. Smith

2007-01-01

178

YOU'RE INVITED... UNLV Narrow Diameter Overdenture Implants 101  

E-print Network

of the University of Pennsylvania. He served as an Attending Staff Dentist, Chief of Restorative Dentistry. Dr. Ingel has interests in both the surgical and restorative aspects if implant dentistry articles related to clinical prosthodontics, implant dentistry, and digital technology with a special

Hemmers, Oliver

179

Biomaterials 26 (2005) 35113519 Fabrication and biocompatibility of polypyrrole implants  

E-print Network

Biomaterials 26 (2005) 3511­3519 Fabrication and biocompatibility of polypyrrole implants suitable Center for Learing and Memory, Massachusetts Institute of Technology, Cambridge, MA 02142, USA c Caritas scaffolds, electrodes, and devices. Stand-alone polymer implants also provide the additional advantages

Sur, Mriganka

180

Characterization of the Edge Crack Torsion (ECT) Test for Mode III Fracture Toughness Measurement of Laminated Composites  

NASA Technical Reports Server (NTRS)

The edge crack torsion (ECT) test is designed to initiate mode III delamination growth in composite laminates. An ECT specimen is a rectangular laminate, containing an edge delamination at the laminate mid-plane. Torsion load is applied to the specimens, resulting in relative transverse shear sliding of the delaminated faces. The test data reduction schemes are intended to yield initiation values of critical mode III strain energy release rate, G(sub IIIc), that are constant with delamination length. The test has undergone several design changes during its development. The objective of this paper was to determine the suitability of the current ECT test design as a mode III fracture test. To this end, ECT tests were conducted on specimens manufactured from IM7/8552 and specimens made from S2/8552 tape laminates. Several specimens, each with different delamination lengths are tested. Detailed, three-dimensional finite element analyses of the specimens were performed. The analysis results were used to calculate the distribution of mode I, mode II, and mode III strain energy release rate along the delamination front. The results indicated that mode III-dominated delamination growth would be initiated from the specimen center. However, in specimens of both material types, the measured values of G(sub IIIc) exhibited significant dependence on delamination length. Furthermore, there was a large amount of scatter in the data. Load-displacement response of the specimens exhibited significant deviation from linearity before specimen failure. X-radiographs of a sample of specimens revealed that damage was initiated in the specimens prior to failure. Further inspection of the failure surfaces is required to identify the damage and determine that mode III delamination is initiated in the specimens.

Ratcliffe, James G.

2004-01-01

181

E!ects of chronic non-clinical depression on the use of positive and negative words in language contexts  

Microsoft Academic Search

The purpose of this study was to investigate the e!ects of chronic non-clinical depression (ChD) on the use of ambiguous and unambiguous emotional words in language contexts. Participants with ChD and normal non-depressed (ND) participants! responses to positive and negative stimulus words on a free association word test were compared using the Hyperspace Analogue to Language (HAL) model of memory!

Janette Alison; Curt Burgess

2003-01-01

182

Modulation of motion after-e¡ect by transcranial direct current stimulation over MT + \\/V5 in humans  

Microsoft Academic Search

While there is strong evidence for the central role of the human MT + \\/V5 in motion processing, its involvement in motion adapta- tion is still the subject of debate. We used transcranial direct cur- rent stimulation (tDCS) to test whether MT + \\/V5 is part of the neural network involved in the long-term adaptation-induced mo- tion after-e¡ect in humans.

Andrea Antal; Edina T. Varga; Michael A. Nitsche; Zoltan Chadaide; Gyula Kovacs

183

Signal Evaluation System of Flexible Array Ect Probes for Inspecting Complexly Shaped Surfaces  

NASA Astrophysics Data System (ADS)

We developed a signal evaluation system of flexible array eddy current testing (ECT) probes for inspecting complexly shaped metal surfaces. Our probes employ excitation and pickup coil pairs arrayed on a bendable substrate to measure curved targets. Since the developed probes produce signals due to the change in the relative position between the coil pair, an evaluation module for flaw signal identification is integrated into the system. The identification utilizes signal phase combination of the coil pairs. It is represented as a two-dimensional diagram constituting the phase values of two of the coil pairs with different positions. The phase of signals around flaws is significantly affected by their orientations. The diagram is therefore capable of separating flaw information from other information and of imaging flaw positions. We applied the system to complex geometric mock-ups. Flaw signals were successfully identified and the images obtained for identified positions could be used to efficiently measure the length of surface flaws by the 12 decibel down method.

Endo, H.; Nishimizu, A.; Tooma, M.; Ouchi, H.; Yoshida, I.; Nonaka, Y.; Otani, K.

2011-06-01

184

Characterization of the Edge Crack Torsion (ECT) Test for Mode III Fracture Toughness Measurement of Laminated Composites  

NASA Technical Reports Server (NTRS)

The edge crack torsion (ECT) test is designed to initiate mode III delamination growth in composite laminates. The test has undergone several design changes during its development. The objective of this paper was to determine the suitability of the current ECT test design a mode III fracture test. To this end, ECT tests were conducted on specimens manufactured from IM7/8552 and S2/8552 tape laminates. Three-dimensional finite element analyses were performed. The analysis results were used to calculate the distribution of mode I, mode II, and mode III strain energy release rate along the delamination front. The results indicated that mode IIIdominated delamination growth would be initiated from the specimen center. However, in specimens of both material types, the measured values of GIIIc exhibited significant dependence on delamination length. Load-displacement response of the specimens exhibited significant deviation from linearity before specimen failure. X-radiographs of a sample of specimens revealed that damage was initiated in the specimens prior to failure. Further inspection of the failure surfaces is required to identify the damage and determine that mode III delamination is initiated in the specimens.

Ratcliffe, James G.

2004-01-01

185

Impression techniques for implant dentistry  

Microsoft Academic Search

The object of making an impression in implant dentistry is to accurately relate an analogue of the implant or implant abutment to the other structures in the dental arch. This is affected by use of an impression coping which is attached to the implant or implant abutment. This impression coping is incorporated in an impression – much as a metal

S Jivraj; W Chee

2006-01-01

186

Multi-Gate Fin Field-Effect Transistors Junctions Optimization by Conventional Ion Implantation for (Sub-)22 nm Technology Nodes Circuit Applications  

NASA Astrophysics Data System (ADS)

In this work we explore several doping schemes for aggressively scaled multi-gate field-effect transistor devices with the conduction channels wrapped around silicon fins (FinFETs) (HFin?37 nm, WFin?10 nm, Lg?30 nm), using conventional ion implantation (I/I), and suitable for both logic and dense circuit applications. We demonstrate that low-energy and: 1) low-tilt, double-sided extension(-less) I/I, or 2) high-tilt, single-sided extension I/I schemes can enable pitch scaling without resist shadowing effects, with no penalty in device performance and yielding higher six transistors-static random access memory (6T-SRAM) static noise margin (SNM) values. Key advantages of the extension-less approach are: reduced cost and cycle time with 2 less critical I/I photos, enabling better quality, defect-free growth of Si-epitaxial raised source/drain (SEG), and up to 20× lower IOFF. It, however, requires a tight spacer critical dimension (CD) control, a less critical parameter for the single-sided I/I scheme, which also allows wider overlay margins.

Veloso, Anabela; De Keersgieter, An; Brus, Stephan; Horiguchi, Naoto; Absil, Philippe P.; Hoffmann, Thomas

2011-04-01

187

Music Perception with Cochlear Implants: A Review  

PubMed Central

The acceptance of cochlear implantation as an effective and safe treatment for deafness has increased steadily over the past quarter century. The earliest devices were the first implanted prostheses found to be successful in compensating partially for lost sensory function by direct electrical stimulation of nerves. Initially, the main intention was to provide limited auditory sensations to people with profound or total sensorineural hearing impairment in both ears. Although the first cochlear implants aimed to provide patients with little more than awareness of environmental sounds and some cues to assist visual speech-reading, the technology has advanced rapidly. Currently, most people with modern cochlear implant systems can understand speech using the device alone, at least in favorable listening conditions. In recent years, an increasing research effort has been directed towards implant users’ perception of nonspeech sounds, especially music. This paper reviews that research, discusses the published experimental results in terms of both psychophysical observations and device function, and concludes with some practical suggestions about how perception of music might be enhanced for implant recipients in the future. The most significant findings of past research are: (1) On average, implant users perceive rhythm about as well as listeners with normal hearing; (2) Even with technically sophisticated multiple-channel sound processors, recognition of melodies, especially without rhythmic or verbal cues, is poor, with performance at little better than chance levels for many implant users; (3) Perception of timbre, which is usually evaluated by experimental procedures that require subjects to identify musical instrument sounds, is generally unsatisfactory; (4) Implant users tend to rate the quality of musical sounds as less pleasant than listeners with normal hearing; (5) Auditory training programs that have been devised specifically to provide implant users with structured musical listening experience may improve the subjective acceptability of music that is heard through a prosthesis; (6) Pitch perception might be improved by designing innovative sound processors that use both temporal and spatial patterns of electric stimulation more effectively and precisely to overcome the inherent limitations of signal coding in existing implant systems; (7) For the growing population of implant recipients who have usable acoustic hearing, at least for low-frequency sounds, perception of music is likely to be much better with combined acoustic and electric stimulation than is typical for deaf people who rely solely on the hearing provided by their prostheses. PMID:15497033

McDermott, Hugh J.

2004-01-01

188

First Results from the Radiation Belt Storm Probes (RBSP) - Energetic particle, Composition, and Thermal plasma (ECT) Suite Science Investigation  

NASA Astrophysics Data System (ADS)

The Radiation Belt Storm Probes (RBSP) - Energetic Particle, Composition, and Thermal Plasma (ECT) suite contains a well-proven complement of particle instruments to ensure the highest quality measurements ever made in the radiation belts and the inner magnetosphere. The coordinated ECT particle measurements, analyzed in combination with fields and waves observations and state-of-the-art theory and modeling, provide new understanding on the acceleration, global distribution, and variability of radiation belt electrons and ions, key science objectives of NASA's Living With a Star program and the RBSP mission. The RBSP-ECT suite consists of three highly-coordinated instruments: the Helium Oxygen Proton Electron (HOPE) spectrometer, the Magnetic Electron Ion Spectrometer (MagEIS), and the Relativistic Electron Proton Telescope (REPT). Collectively they cover comprehensively the full electron and ion spectra from one eV to 10's of MeV with sufficient energy resolution, pitch angle coverage and resolution, and with composition measurements in the critical energy range up to 50 keV and also from a few to 50 MeV/nucleon. All three instruments are based on measurement techniques proven in the radiation belts, then optimized to provide unambiguous separation of ions and electrons and clean energy responses even in the presence of extreme penetrating background environments. In this presentation, we summarize overall ECT science questions and then show first scientific results derived from the ECT suite on the dual RBSP spacecraft. We anticipate that these results will include progress toward resolving primary RBSP science targets, such as: the relative role of localized acceleration versus transport-generated particle acceleration; the role of plasma electron temperature anisotropies, whistler waves, and radiation belt electron variability; global characteristics of outer zone electron drift loss to the magnetopause; the role of storms, substorms, and ion composition in radiation belt dynamics, both in terms of sources and sinks; new physical perspectives on inner zone and slot protons and electrons; and, how plasmasphere properties control or influence radiation belt behavior.

Spence, H. E.; Reeves, G. D.

2012-12-01

189

Who Is an Implant Candidate?  

MedlinePLUS

Who Is an Implant Candidate? If you're interested in replacing a missing tooth or teeth, dental implants may be an option for you. Most people are good candidates for implants. A good candidate should have the following: Healthy ...

190

Analysis of the procedures for selection of children for the cochlear implant.  

E-print Network

??Cochlear implants are high- technology electronic devices that electrically stimulate remaining nervous fibers, allowing the transmission of electric signals to the auditory nerve for codification… (more)

Elaine Soares Monteiro Pinto

2007-01-01

191

Implantable flexible wireless pressure sensor module  

Microsoft Academic Search

A chip embedded flexible packaging scheme has been developed using a thinned silicon chip. Mechanical characteristics of thinned silicon chips are examined by bending test and finite element analysis. Thinned silicon chips (t<50 ?m) are fabricated by a chemical etching process to avoid possible surface damage. These technologies can be used for an implantable real-time monitoring of blood pressure. Our

Kyu-Ho Shin; Chang-Youl Moon; Tae-Hee Lee; Chang-Hyun Lim; Young-Jun Kim

2004-01-01

192

Implant therapy using ultraspeed CO2 lasers.  

PubMed

tial applications are very beneficial clinically. As the technology improves, different wavelengths and laser mediums exhibit advantages and disadvantages in those clinical applications. The purpose of this article is to discuss the use of the CO2 UltraSpeed Laser for implant dentistry as well as how it compares, in the author's opinion, to other soft tissue PMID:17039679

Julian, Jon M

2005-09-01

193

Smoking and dental implants  

PubMed Central

Smoking is a prevalent behaviour in the population. The aim of this review is to bring to light the effects of smoking on dental implants. These facts will assist dental professionals when implants are planned in tobacco users. A search of “PubMed” was made with the key words “dental implant,” “nicotine,” “smoking,” “tobacco,” and “osseointegration.” Also, publications on tobacco control by the Government of India were considered. For review, only those articles published from 1988 onward in English language were selected. Smoking has its influence on general as well as oral health of an individual. Tobacco negatively affects the outcome of almost all therapeutic procedures performed in the oral cavity. The failure rate of implant osseointegration is considerably higher among smokers, and maintenance of oral hygiene around the implants and the risk of peri-implantitis are adversely affected by smoking. To increase implant survival in smokers, various protocols have been recommended. Although osseointegrated dental implants have become the state of the art for tooth replacement, they are not without limitations or complications. In this litigious era, it is extremely important that the practitioner clearly understands and is able and willing to convey the spectrum of possible complications and their frequency to the patients. PMID:24478965

Kasat, V.; Ladda, R.

2012-01-01

194

Cochlear implants in children.  

PubMed

In recent years, the House single-electrode cochlear implant has proven to be a clinically feasible prosthesis for profoundly deaf adults. Based on these findings, the decision was made to begin implanting those children who could not benefit from hearing aids. As of August 1982, 23 profoundly deaf children (ranging in age from 3.4 to 17.5 yrs) have received the cochlear implant. The majority were deafened by meningitis. Results to date indicate that children demonstrate sound field thresholds and receive timing/intensity information comparable to that of adult implant patients. Results have been extremely encouraging, but only long-term experience will determine the ultimate benefit of the implant in children. PMID:6687579

Eisenberg, L S; Berliner, K I; Thielemeir, M A; Kirk, K I; Tiber, N

1983-01-01

195

Implant over implant: An alternative method for solving malpositioned osseointegrated implants at the sinus floor.  

PubMed

An implant was malpositioned and osseointegrated at the maxillary sinus floor with no complications. However, unexpected bone formation over the implant made the implant nonfunctional. Because the patient rejected the removal of the implant, it was left in place while another short implant was placed into the newly formed bone in approximately the same position as the old implant to restore the posterior maxillary tooth. Within 6 months, the new implant over the old asymptomatic implant was functional. Radiographs revealed osseointegration and stable periimplant marginal bone level with no signs of infection or inflammation. PMID:24819533

Man, Yi; Wang, Tianlu; Mo, Anchun; Qu, Yili

2014-10-01

196

Peri-implant mucositis and peri-implantitis: bacterial infection.  

PubMed

Osseointegrated dental implants have a ong-term success rate of over 90%, but may be threatened by peri-implant mucostis and peri-implantitis, bacteria biofilm-induced inflammatory conditions. While peri-implant mucositis is a reversible inflammatory condition confined to the peri-implant soft-tissue unit, peri-implantitis is characterised by progressive inflammatory destruction of the crest of the alveolar bone supporting the implant, by increased peri-implant probing depths, and by bleeding and/or suppuration on probing. Effective treatment of peri-implant mucositis will prevent the development of peri-implantitis. Plaque accumulation on the implant/abutment surface juxtaposed to the junctional epithelium and to the connective tissue zone of the peri-implant soft-tissue unit induces the development of peri-implant mucositis which can subsequently progress to peri-implantitis. The aim of this paper is to review some aspects of bacterial infection of the tissue supporting dental implants, and to explore how to maintain the healthy peri-implant soft-tissue unit. PMID:23189895

Khammissa, R A G; Feller, L; Meyerov, R; Lemmer, J

2012-03-01

197

[Implantable ventricular assist device].  

PubMed

Implantable ventricular assist device( VAD) is the only evidence-based option to treat stage D heart failure patients with significant symptoms at rest in spite of maximum medical therapy, other than heart transplant. Implantable VADs available in Japan include Evaheart, DuraHeart both from Japan, Jarvik 2000 and HeartMate II both from United States. In Japanese settings, implantable VAD is indicated and insured only for patients who are supposed to have an indication for receiving heart transplant, which means "bridge to transplantation" use. And in Japan, implantable VAD can be implanted for patients less than 65 years old if it needs to be insured. In the University of Tokyo Hospital, the mid-term outcomes of 41 implantable VAD patients were acceptable with 2 hospital deaths, 2 remote deaths and oneyear survival rate at 88%.Considering the present Japanese situation with extreme shortage of organ donation, the extended application of implantable VADs as "Destination Therapy" is awaited, but quality of life of care-givers as well as patients themselves and sustainable follow-up system provided by healthcare professionals need to be warranted. PMID:25138935

Nawata, Kan; Kinoshita, Osamu; Kimura, Mitsutoshi; Ono, Minoru

2014-07-01

198

Electrical capacitance tomography (ECT) and gamma radiation meter for comparison with and validation and tuning of computational fluid dynamics (CFD) modeling of multiphase flow  

NASA Astrophysics Data System (ADS)

The electrical capacitance tomographic (ECT) approach is increasingly seen as attractive for measurement and control applications in the process industries. Recently, there is increased interest in using the tomographic details from ECT for comparing with and validating and tuning CFD models of multiphase flow. Collaboration with researchers working in the field of computational fluid dynamics (CFD) modeling of multiphase flows gives valuable information for both groups of researchers in the field of ECT and CFD. By studying the ECT tomograms of multiphase flows under carefully monitored inflow conditions of the different media and by obtaining the capacitance values, C(i, j, t) with i = 1…N, j = 1,?2,…N and i ? j obtained from ECT modules with N electrodes, it is shown how the interface heights in a pipe with stratified flow of oil and air can be fruitfully compared to the values of those obtained from ECT and gamma radiation meter (GRM) for improving CFD modeling. Monitored inflow conditions in this study are flow rates of air, water and oil into a pipe which can be positioned at varying inclinations to the horizontal, thus emulating the pipelines laid in subsea installations. It is found that ECT-based tomograms show most of the features seen in the GRM-based visualizations with nearly one-to-one correspondence to interface heights obtained from these two methods, albeit some anomalies at the pipe wall. However, there are some interesting features the ECT manages to capture: features which the GRM or the CFD modeling apparently do not show, possibly due to parameters not defined in the inputs to the CFD model or much slower response of the GRM. Results presented in this paper indicate that a combination of ECT and GRM and preferably with other modalities with enhanced data fusion and analysis combined with CFD modeling can help to improve the modeling, measurement and control of multiphase flow in the oil and gas industries and in the process industries in general. This article was invited for the special feature on Imaging Systems and Techniques 2012, published in July 2013.

Pradeep, Chaminda; Yan, Ru; Vestøl, Sondre; Melaaen, Morten C.; Mylvaganam, Saba

2014-07-01

199

Transcatheter aortic valve implantation  

PubMed Central

Transcatheter aortic valve implantation was developed to offer a therapeutic solution to patients with severe symptomatic aortic stenosis who are not candidates for conventional aortic valve replacement. The improvement in transcatheter aortic valve implantation outcomes is still of concern in the areas of stroke, vascular injury, heart block, paravalvular regurgitation and valve durability. Concomitantly, the progress, both technical and in terms of material advances of transcatheter valve systems, as well as in patient selection, renders transcatheter aortic valve implantation an increasingly viable treatment for more and more patients with structural heart disease. PMID:25374670

Oliemy, Ahmed

2014-01-01

200

Implantable defibrillators: 30 years of history.  

PubMed

The first concept of an implantable defibrillator was published in 1970 by Dr. Michel Mirowski and his colleague and friend Dr. Morton Mower. Within 30 years implantable defibrillator therapy has gone through a breathtaking development. However, it started with a vision and a concept of one man, who went through difficult times, personally, and in his intention to make his idea of a device that prevents sudden death come true. As with other innovative approaches in medicine, in the beginning there were more opponents than supporters of the concept. Device technology has impressively improved, but the principal concept remained the same: automatic shock delivery to a fibrillating heart by an implanted defibrillator will restore normal heart rhythm and save the life of the patient. PMID:21416749

Klein, Helmut U; Inama, Giuseppe

2010-10-01

201

Dental implants from functionally graded materials.  

PubMed

Functionally graded material (FGM) is a heterogeneous composite material including a number of constituents that exhibit a compositional gradient from one surface of the material to the other subsequently, resulting in a material with continuously varying properties in the thickness direction. FGMs are gaining attention for biomedical applications, especially for implants, owing to their reported superior composition. Dental implants can be functionally graded to create an optimized mechanical behavior and achieve the intended biocompatibility and osseointegration improvement. This review presents a comprehensive summary of biomaterials and manufacturing techniques researchers employ throughout the world. Generally, FGM and FGM porous biomaterials are more difficult to fabricate than uniform or homogenous biomaterials. Therefore, our discussion is intended to give the readers about successful and obstacles fabrication of FGM and porous FGM in dental implants that will bring state-of-the-art technology to the bedside and develop quality of life and present standards of care. PMID:23754641

Mehrali, Mehdi; Shirazi, Farid Seyed; Mehrali, Mohammad; Metselaar, Hendrik Simon Cornelis; Kadri, Nahrizul Adib Bin; Osman, Noor Azuan Abu

2013-10-01

202

Technologies  

Microsoft Academic Search

The problem of information and knowledge management in the knowledge intensive and time critical environment of law enforcement has posed an interesting problem for information technology professionals in the field. Coupled with this challenging environment are issues relating to the integration of multiple systems, each having different functionalities resulting in difficulty for the end-user. The COPLINK project ties together the

Roslin V. Hauck; Hsinchun Chen

203

Annealing of PEEK, PET and PI implanted with Co ions at high fluencies  

NASA Astrophysics Data System (ADS)

The properties of implanted polymers strongly depend on the implantation ion fluence and on the properties of the implanted atoms. The stability of synthesized nano-structures during further technological steps like annealing is of importance for their possible applications. Polyimide (PI), polyetheretherketone (PEEK), and polyethyleneterephtalate (PET) were implanted with 40 keV Co+ ions at room temperature at fluences ranging from 0.2 × 1016 cm-2 to 1.0 × 1017 cm-2 and annealed at a temperature of 200 °C. The implanted depth profiles of as-implanted and annealed samples, determined by the RBS method, were compared with the results of SRIM 2012 simulations. The structural and compositional changes of the implanted and subsequently annealed polymers were characterized by RBS and UV-vis spectroscopy. The surface morphology of as-implanted and annealed samples was examined by the AFM method and their electrical properties by sheet resistance measurement.

Mackova, A.; Malinsky, P.; Miksova, R.; Pupikova, H.; Khaibullin, R. I.; Valeev, V. F.; Svorcik, V.; Slepicka, P.

2013-07-01

204

[Dental implants and their materials].  

PubMed

Some new trends in materials for dental implants, which also effect in the operative techniques and implant design, are described. Advantages and shortcomings of the different material types are exemplified and correlated with their bioinert resp. bioactive functions. The practical interest in metallic implants focussed in titanium resp. oxide ceramics in the ceramic field, whereas the special goal of implant research follows from the improvement of the bioactive principle with loaded calcium phosphate implants. PMID:6350895

Newesely, H

1983-07-01

205

Ion implantation at elevated temperatures  

SciTech Connect

A kinetic model has been developed to investigate the synergistic effects of radiation-enhanced diffusion, radiation-induced segregation and preferential sputtering on the spatial redistribution of implanted solutes during implantation at elevated temperatures. Sample calculations were performed for Al and Si ions implanted into Ni. With the present model, the influence of various implantation parameters on the evolution of implant concentration profiles could be examined in detail.

Lam, N.Q.; Leaf, G.K.

1985-11-01

206

Implantable Medical Devices  

MedlinePLUS

... A left ventricular assist device (LVAD) is a battery-operated, mechanical pump-type device that's surgically implanted. ... of the body and attached to the pump's battery and control system. LVADs are now portable and ...

207

Implant-Supported Denture  

MedlinePLUS

... or 6 (denture needed to be made) Standard abutments connected to the tops of the implants Once ... material will secure the denture to the healing abutments. About two weeks after the second procedure, the ...

208

Technologies Technologies  

E-print Network

UFR Sciences et Technologies UFR Sciences et Technologies UFR SCIENCES ET TECHNOLOGIES Département ETUDIE *-*-*-*-*-*-*-* #12;UFR Sciences et Technologies UFR Sciences et Technologies Dossier de-baccalauréat : ANNEE DUREE ENTREPRISE SUJET #12;UFR Sciences et Technologies UFR Sciences et Technologies Dossier de

Sart, Remi

209

[Larynx: implants and stents].  

PubMed

There is a wide variety of devices and materials to be implanted into the human larynx. Some are intended to remain only for a period of time, like laryngeal stents. If removal is not intended the device meets the definition for a medical implant. The majority of implants is used for the treatment of unilateral vocal fold immobility. There a 2 types of implants serving this purpose: Implants in a stricter sense are devices of solid material, which are brought into the paraglottic space through a window in the laryngeal framework (medialization thyroplasty). Several different products are presented in this review. In contrast, there are different substances available for endoscopic injection into the paralyzed vocal fold (injection laryngoplasty). Since some of these substances show a corpuscular consistency and a high viscosity they need to be deposited into the lateral paraglottic space. Therefore, the term "injectable implants" has been coined for these materials. The different substances available are discussed in detail in this review. Laryngeal stents are primarily used in the early postoperative phase after open reconstruction of the larynx. The different devices available on the market are described with their specific characteristics and intended use. PMID:19353452

Sittel, C

2009-05-01

210

Science and technology news Nanotechnology  

E-print Network

Science and technology news Home Nanotechnology Physics Space & Earth Electronics Technology Chemistry Biology Medicine & Health Other Sciences Psychology & Psychiatry Research Medications Cancer of neurology at the University of Pennsylvania School of Medicine in Philadelphia. The silk-based implants

Rogers, John A.

211

The Biolink Implantable Telemetry System  

NASA Technical Reports Server (NTRS)

Most biotelemetry applications deal with the moderated data rates of biological signals. Few people have studied the problem of transcutaneous data transmission at the rates required by NASA's Life Sciences-Advanced BioTelemetry System (LS-ABTS). Implanted telemetry eliminate the problems associated with wire breaking the skin, and permits experiments with awake and unrestrained subjects. Our goal is to build a low-power 174-216MHz Radio Frequency (RF) transmitter suitable for short range biosensor and implantable use. The BioLink Implantable Telemetry System (BITS) is composed of three major units: an Analog Data Module (ADM), a Telemetry Transmitter Module (TTM), and a Command Receiver Module (CRM). BioLink incorporates novel low-power techniques to implement a monolithic digital RF transmitter operating at 100kbps, using quadrature phase shift keying (QPSK) modulation in the 174-216MHz ISM band. As the ADM will be specific for each application, we focused on solving the problems associated with a monolithic implementation of the TTM and CRM, and this is the emphasis of this report. A system architecture based on a Frequency-Locked Loop (FLL) Frequency Synthesizer is presented, and a novel differential frequency that eliminates the need for a frequency divider is also shown. A self sizing phase modulation scheme suitable for low power implementation was also developed. A full system-level simulation of the FLL was performed and loop filter parameters were determined. The implantable antenna has been designed, simulated and constructed. An implant package compatible with the ABTS requirements is also being proposed. Extensive work performed at 200MHz in 0.5um complementary metal oxide semiconductors (CMOS) showed the feasibility of integrating the RF transmitter circuits in a single chip. The Hajimiri phase noise model was used to optimize the Voltage Controlled Oscillator (VCO) for minimum power consumption. Two test chips were fabricated in a 0.5pm, 3V CMOS process. Measured phase noise for a 1.5mW, 200MHz ring oscillator VCO is -80dBc/Hz at 100KHZ offset, showing good agreement with the theory. We also propose a novel superregenerative receiver architecture for implementing the command receiver. The superregenerative receiver's simplicity, low cost, and low power consumption has made it the receiver of choice for short-distance data communications, remote control and home automation. We present the design of a superregenerative AM receiver implemented in a 0.5um CMOS technology that operates at 433.92MHz and dissipates only 300uW. Further work entails detailed transistor-level design of the FLL and superregenerative receiver and a monolithic implementation of an implantable transceiver in 0.5um CMOS technology.

Betancourt-Zamora, Rafael J.

1999-01-01

212

Effects of MPII-implanted titanium on the electrochromic properties of tungsten trioxide  

NASA Astrophysics Data System (ADS)

There are great interests in electrochromic (EC) technology for smart windows and displays over the last decade. The substrate, a conductive glass being coated indium tin oxide (ITO) thin films, deposited tungsten trioxide (WO 3) using radio-frequency (RF) sputtering and implanted Ti by a metal-plasma ion implantation (MPII) in this study. The optical density (when the implanted dose is less than 2 × 10 15 ions/cm 2) is approximately 1.6 times the unimplanted Ti. At low implanted dose +6 valence tungsten ions improve optical density. At high implanted dose, low-valence tungsten ions reduce the optical density.

Weng, Ko-Wei; Han, Sheng; Chen, Ya-Chi; Chuang, Han-Chun

2008-04-01

213

The ectD Gene, Which Is Involved in the Synthesis of the Compatible Solute Hydroxyectoine, Is Essential for Thermoprotection of the Halophilic Bacterium Chromohalobacter salexigens  

PubMed Central

The halophilic bacterium Chromohalobacter salexigens synthesizes and accumulates compatible solutes in response to salt and temperature stress. 13C-nuclear magnetic resonance analysis of cells grown in minimal medium at the limiting temperature of 45°C revealed the presence of hydroxyectoine, ectoine, glutamate, trehalose (not present in cells grown at 37°C), and the ectoine precursor, N?-acetyldiaminobutyric acid. High-performance liquid chromatography analyses showed that the levels of ectoine and hydroxyectoine were maximal during the stationary phase of growth. Accumulation of hydroxyectoine was up-regulated by salinity and temperature, whereas accumulation of ectoine was up-regulated by salinity and down-regulated by temperature. The ectD gene, which is involved in the conversion of ectoine to hydroxyectoine, was isolated as part of a DNA region that also contains a gene whose product belongs to the AraC-XylS family of transcriptional activators. Orthologs of ectD were found within the sequenced genomes of members of the proteobacteria, firmicutes, and actinobacteria, and their products were grouped into the ectoine hydroxylase subfamily, which was shown to belong to the superfamily of Fe(II)- and 2-oxoglutarate-dependent oxygenases. Analysis of the ectoine and hydroxyectoine contents of an ectABC ectD mutant strain fed with 1 mM ectoine or hydroxyectoine demonstrated that ectD is required for the main ectoine hydroxylase activity in C. salexigens. Although in minimal medium at 37°C the wild-type strain grew with 0.5 to 3.0 M NaCl, with optimal growth at 1.5 M NaCl, at 45°C it could not cope with the lowest (0.75 M NaCl) or the highest (3.0 M NaCl) salinity, and it grew optimally at 2.5 M NaCl. The ectD mutation caused a growth defect at 45°C in minimal medium with 1.5 to 2.5 M NaCl, but it did not affect growth at 37°C at any salinity tested. With 2.5 M NaCl, the ectD mutant synthesized 38% (at 37°C) and 15% (at 45°C) of the hydroxyectoine produced by the wild-type strain. All of these data reveal that hydroxyectoine synthesis mediated by the ectD gene is thermoregulated and essential for thermoprotection of C. salexigens. PMID:16707670

Garcia-Estepa, Raul; Argandona, Montserrat; Reina-Bueno, Mercedes; Capote, Nieves; Iglesias-Guerra, Fernando; Nieto, Joaquin J.; Vargas, Carmen

2006-01-01

214

[Dental implant-related infections].  

PubMed

Dental implant-associated infections are expected to be increasingly more common as the number of patients with implants for more than 10 years rises. There are 2 stages of peri-implant infection: early mucositis, consisting of inflammation of the peri-implant soft tissues without loss of supporting bone, and a more advanced form involving a loss of osseointegration, known as peri-implantitis. The estimated prevalence of this latter infection is 10% of 5-year implants and the main risk factor is previous periodontal disease. The etiopathogenesis of peri-implantitis is related with reservoirs of periodontal pathogens; however factors that lead to colonization of the implant surface or increased susceptibility to infection may also have an influence. Treatment should include removal of the bacterial biofilm, debridement of the exposed surface, and surgical regeneration of the peri-implant pocket. PMID:19100180

López-Cerero, Lorena

2008-11-01

215

Physics of Plasma-Based Ion Implantation & Deposition (PBIID) and High Power Impulse Magnetron Sputtering (HIPIMS): A Comparison  

E-print Network

G. Lister, Plasma Sources Science and Technology 6/4 (1997)established technology of Plasma Based Ion Implantation &technology emerged in the 1980s when Adler and Picraux [3] used (pulsed) metal plasma and

Anders, Andre

2008-01-01

216

Modulation Techniques for Biomedical Implanted Devices and Their Challenges  

PubMed Central

Implanted medical devices are very important electronic devices because of their usefulness in monitoring and diagnosis, safety and comfort for patients. Since 1950s, remarkable efforts have been undertaken for the development of bio-medical implanted and wireless telemetry bio-devices. Issues such as design of suitable modulation methods, use of power and monitoring devices, transfer energy from external to internal parts with high efficiency and high data rates and low power consumption all play an important role in the development of implantable devices. This paper provides a comprehensive survey on various modulation and demodulation techniques such as amplitude shift keying (ASK), frequency shift keying (FSK) and phase shift keying (PSK) of the existing wireless implanted devices. The details of specifications, including carrier frequency, CMOS size, data rate, power consumption and supply, chip area and application of the various modulation schemes of the implanted devices are investigated and summarized in the tables along with the corresponding key references. Current challenges and problems of the typical modulation applications of these technologies are illustrated with a brief suggestions and discussion for the progress of implanted device research in the future. It is observed that the prime requisites for the good quality of the implanted devices and their reliability are the energy transformation, data rate, CMOS size, power consumption and operation frequency. This review will hopefully lead to increasing efforts towards the development of low powered, high efficient, high data rate and reliable implanted devices. PMID:22368470

Hannan, Mahammad A.; Abbas, Saad M.; Samad, Salina A.; Hussain, Aini

2012-01-01

217

The use of ion implantation for materials processing  

NASA Astrophysics Data System (ADS)

This report is the sixth in a series of Progress Reports on work conducted at the Naval Research Laboratory (NRL) to investigate the use of ion implantation for materials processing. The objective of the program is to develop the capabilities of ion implantation and ion beam activated deposition for new and improved surface treatment techniques of interest to Navy and DOD applications. Attainment of this objective requires both fundamental research to provide an understanding of the physical and metallurgical changes taking place in the implanted region of a material and applications oriented research to demonstrate the benefits of ion implantation. The purpose of this report is to make available from one source the results of all studies at NRL related to the use of ion implantation for materials processing so as to provide a more comprehensive picture of the scope and interrelationship of the research and to expedite technology transfer to the civilian industrial sector. The report consists of four sections describing the research and a cummulative bibliography of published papers and reports. This report describes the important factors in ion implantation science and technology and reports progress in the use of ion implantation to modify friction, wear, fatigue, corrosion, optical and magnetic properties of materials.

Smidt, F. A.

1986-03-01

218

Nanostructured ceramics for biomedical implants.  

PubMed

Recent progress in the synthesis, characterization, and biological compatibility of nanostructured ceramics for biomedical implants is reviewed. A major goal is to develop ceramic coating technology that can reduce the friction and wear in mating total joint replacement components, thus contributing to their significantly improved function and longer life span. Particular attention is focused on the enhancement of mechanical properties such as hardness, toughness, and friction coefficient and on the bioactivity as they pertain to the nanostructure of the material. The development of three nanostructured implant coatings is discussed: diamond, hydroxyapatite, and functionally graded metalloceramics based on the Cr-Ti-N ternary system. Nanostructured diamond produced by chemical vapor deposition (CVD) techniques and composed of nano-size diamond grains have particular promise because of the combination of ultrahigh hardness, improved toughness over conventional microcrystalline diamond, low friction, and good adhesion to titanium alloys. Nanostructured processing applied to hydroxyapatite coatings is used to achieve the desired mechanical characteristics and enhanced surface reactivity and has been found to increase osteoblast adhesion, proliferation, and mineralization. Finally, nanostructured metalloceramic coatings provide continuous variation from a nanocrystalline metallic bond at the interface to the hard ceramic bond on the surface and have the ability to overcome adhesion problems associated with ceramic hard coatings on metallic substrates. PMID:12908255

Catledge, Shane A; Fries, Marc D; Vohra, Yogesh K; Lacefield, William R; Lemons, Jack E; Woodard, Shanna; Venugopalan, Ramakrishna

2002-01-01

219

Application of Cluster Boron Implantation to pMOSFETs  

NASA Astrophysics Data System (ADS)

We applied B18HX+ as an alternation of B+ or BF2+ to the implantation for source-drain extension in pMOSFETs corresponding to various technology nodes from 65 nm to 28 nm. We could obtain identical or better characteristics compared to the cases of conventional ions. In addition, we found from blank wafer that larger impact damage to Si atoms in B18HX+ implantation leads to more advantageous Rs-Xj in activation processing with only MSA.

Kawasaki, Y.; Ishibashi, M.; Kitazawa, M.; Maruyama, Y.; Endo, S.; Yamashita, T.; Kuroi, T.

2011-01-01

220

Laser Additive Manufacturing of Modified Implant Surfaces with Osseointegrative Characteristics  

Microsoft Academic Search

Additive Manufacturing technology, such as Selective Laser Melting, allows fabrication of complex metal parts with freeform surfaces. Using biocompatible metal alloys, e.g. TiAl6V4, medical implants can be produced. To increase osseointegrative behavior the ability to fabricate filigree lattice structures can be utilized to achieve a modified implant surface. In order to increase dimensional accuracy when applying a lattice structure on

C. Emmelmann; P. Scheinemann; M. Munsch; V. Seyda

2011-01-01

221

Ion implantation synthesized copper oxide-based resistive memory devices  

Microsoft Academic Search

Copper oxide resistive memory layers have been synthesized by ion implantation. Devices fabricated from off-stoichiometric Cu2O exhibited unipolar switching in forward\\/reverse bias without a forming voltage. The on-state conduction of these devices is likely dominated by a metallic filament, which ruptures via Joule heating to transition the device to the high resistance off-state. Technology scaling was achieved by oxygen implanting

S. M. Bishop; H. Bakhru; S. W. Novak; B. D. Briggs; R. J. Matyi; N. C. Cady

2011-01-01

222

Gender Categorization in Cochlear Implant Users  

E-print Network

information in speech and intense speech therapy following implantation are probably responsible the dissociation between recovery of speech recognition and voice feature perception after cochlear implantation, cochlear implants, gender, speech perception A cochlear implant (CI) is an effective neuroprosthe- sis

223

Clinical experience with downsized lower energy output implantable cardioverter defibrillators  

Microsoft Academic Search

Background and study objective: Technical improvements in cardioverter defibrillators technology has resulted in decrease in can size coupled with improved electrodes technology. A decrease in maximum energy output allows further decrease in device size. The aim of this study was to evaluate the feasibility of a single lead transvenous implant employing a downsized cardioverter-defibrillator (volume 59 cm3), with a related

Giuseppe Boriani; Lorenzo Frabetti; Mauro Biffi; Luciano Sallusti

1998-01-01

224

History of cochlear implantation.  

PubMed

The evolution of cochlear implantation from early experimentation with electrical stimulation of the ear in the 18th century to the sophisticated multichannel device that we now routinely implant has been remarkable. It is a tribute to the perseverance of a number of dedicated scientists in many disciplines who, in the face of serious, but ultimately unfounded, theoretical objections and ethical challenges, were eventually able to restore useful hearing to that large group of profoundly deaf adults and children, who were hitherto untreatable. The transformation in the lives of prelingually deaf children, who are now able to acquire speech and language and fulfil their full educational potential has been particularly spectacular. Cochlear implantation is the greatest advance in the field of otolaryngology in the last hundred years, and in medicine in general is one of the landmark achievements of the 20th century. PMID:24533753

Ramsden, Richard T

2013-11-01

225

MEAT SCIENCE AND MUSCLE BIOLOGY SYMPOSIUM--anabolic implants and meat quality.  

PubMed

Anabolic implants are routinely used in the finishing phase of beef production to improve animal performance and feed efficiency. Implanting during the feedlot phase on average increases ADG 18%, feed intake 6%, feed efficiency 8%, carcass weight 5%, and ribeye area 4% compared with nonimplanted controls. Implants reduce the cost of beef production, which is important given current high feed costs and beef prices. In a 1996 review of 37 implant trials, the use of a combination (i.e., estrogenic and trenbolone acetate) implant increased returns by US$77/head compared with nonimplanted steers. If calculated using today's prices, a combination implant would increase returns by $163/head. However, concerns about potential negative effects of implants on marbling scores, quality grades, and tenderness exist. Changes in Warner-Bratzler shear force values of steaks from implanted steers are small (<0.5 kg) and appear related to an increase in initial tenderness, possibly due to hypertrophy of muscle fiber, instead of alterations in postmortem proteolysis. The increase in ribeye size observed with implanting may also reduce marbling scores through a dilution effect. The impact of anabolic implants on gene expression has shown that implanting downregulates expression of certain lipogenic genes (e.g., stearoyl-CoA desaturase, fatty acid synthetase, fatty acid elongase-6) in steers with low quality grades (Select-) but not in implanted steers with high quality grades (Choice-). Examination of the adipocyte's transcriptome has shown that 36 genes were differentially expressed due to implant treatment. More research is needed to further determine how anabolic implants alter lipogenic gene expression to address changes in marbling deposition with implant usage. Given our current high feed costs and cattle prices, anabolic implants are one of the most cost-effective technologies that can be used in beef production systems. PMID:24243897

Duckett, S K; Pratt, S L

2014-01-01

226

Hydroxylapatite Otologic Implants  

SciTech Connect

A Cooperative Research and Development Agreement (CRADA) between Lockheed Martin Energy Research Corporation (LMER) and Smith and Nephew Richards Inc. of Bartlett, TN, was initiated in March 1997. The original completion date for the Agreement was March 25, 1998. The purpose of this work is to develop and commercialize net shape forming methods for directly creating dense hydroxylapatite (HA) ceramic otologic implants. The project includes three tasks: (1) modification of existing gelcasting formulations to accommodate HA slurries; (2) demonstration of gelcasting to fabricate green HA ceramic components of a size and shape appropriate to otologic implants: and (3) sintering and evaluation of the HA components.

McMillan, A.D.; Lauf, R.J.; Beale, B.; Johnson, R.

2000-01-01

227

The e ects of North Atlantic SST and sea-ice anomalies on the winter circulation in CCM3. Part I: Main features and storm-track  

E-print Network

meridional tilt. In contrast, the storm-track response to the observed sea-ice trend corresponds to a weakerThe e#11;ects of North Atlantic SST and sea-ice anomalies on the winter circulation in CCM3. Part I: Main features and storm-track characteristics of the response Gudrun Magnusdottir 1 Department of Earth

Magnusdottir, Gudrun

228

ReProTool Version 2.0: Re-Engineering Academic Curriculum Using Learning Outcomes, ECTS and Bologna Process Concepts  

ERIC Educational Resources Information Center

Purpose: The purpose of this paper is to present ReProTool Version 2.0, a software tool that is used for the European Credit Transfer System (ECTS) and the Bologna Process re-engineering of academic programmes. The tool is the result of an 18 months project (February 2012-July 2013) project, co-financed by the European Regional Development Fund…

Pouyioutas, Philippos; Gjermundrod, Harald; Dionysiou, Ioanna

2012-01-01

229

Combining Peer-Assessment with Negotiated Learning Activities on a Day-Release Undergraduate-Level Certificate Course (ECTS Level 3)  

ERIC Educational Resources Information Center

Peer-assessment was used within a negotiated curriculum in a module on training and development at ECTS level 3. The students on the programme were exclusively day-release and all had a major responsibility for the management and delivery of work-based training programmes. Analysis of student evaluations, supplemented by those of university…

McMahon, Tim

2010-01-01

230

Focal Electrically Administered Seizure Therapy (FEAST): A novel form of ECT illustrates the roles of current directionality, polarity, and electrode configuration in seizure induction  

PubMed Central

Electroconvulsive therapy (ECT) is a mainstay in the treatment of severe, medication resistant depression. The antidepressant efficacy and cognitive side effects of ECT are influenced by the position of the electrodes on the head and by the degree to which the electrical stimulus exceeds the threshold for seizure induction. However, surprisingly little is known about the effects of other key electrical parameters such as current directionality, polarity, and electrode configuration. Understanding these relationships may inform the optimization of therapeutic interventions to improve their risk/benefit ratio. To elucidate these relationships, we evaluated a novel form of ECT (focal electrically administered seizure therapy, FEAST) that combines unidirectional stimulation, control of polarity, and an asymmetrical electrode configuration, and contrasted it with conventional ECT in a nonhuman primate model. Rhesus monkeys had their seizure thresholds determined on separate days with ECT conditions that crossed the factors of current directionality (unidirectional or bidirectional), electrode configuration (standard bilateral or FEAST (small anterior and large posterior electrode)), and polarity (assignment of anode and cathode in unidirectional stimulation). Ictal expression and post-ictal suppression were quantified via scalp EEG. Findings were replicated and extended in a second experiment with the same subjects. Seizures were induced in each of 75 trials, including 42 FEAST procedures. Seizure thresholds were lower with unidirectional than with bidirectional stimulation (p<0.0001), and lower in FEAST than in bilateral ECS (p=0.0294). Ictal power was greatest in posterior-anode unidirectional FEAST, and post-ictal suppression was strongest in anterior-anode FEAST (p=0.0008 and p=0.0024, respectively). EEG power was higher in the stimulated hemisphere in posterior-anode FEAST (p=0.0246), consistent with the anode being the site of strongest activation. These findings suggest that current directionality, polarity, and electrode configuration influence the efficiency of seizure induction with ECT. Unidirectional stimulation and novel electrode configurations such as FEAST are two approaches to lowering seizure threshold. Furthermore, the impact of FEAST on ictal and post-ictal expression appeared to be polarity-dependent. Future studies may examine whether these differences in seizure threshold and expression have clinical significance for patients receiving ECT. PMID:19225453

Spellman, Timothy; Peterchev, Angel V.; Lisanby, Sarah H.

2009-01-01

231

Synthesis of 5-hydroxyectoine from ectoine: crystal structure of the non-heme iron(II) and 2-oxoglutarate-dependent dioxygenase EctD.  

PubMed

As a response to high osmolality, many microorganisms synthesize various types of compatible solutes. These organic osmolytes aid in offsetting the detrimental effects of low water activity on cell physiology. One of these compatible solutes is ectoine. A sub-group of the ectoine producer's enzymatically convert this tetrahydropyrimidine into a hydroxylated derivative, 5-hydroxyectoine. This compound also functions as an effective osmostress protectant and compatible solute but it possesses properties that differ in several aspects from those of ectoine. The enzyme responsible for ectoine hydroxylation (EctD) is a member of the non-heme iron(II)-containing and 2-oxoglutarate-dependent dioxygenases (EC 1.14.11). These enzymes couple the decarboxylation of 2-oxoglutarate with the formation of a high-energy ferryl-oxo intermediate to catalyze the oxidation of the bound organic substrate. We report here the crystal structure of the ectoine hydroxylase EctD from the moderate halophile Virgibacillus salexigens in complex with Fe(3+) at a resolution of 1.85 A. Like other non-heme iron(II) and 2-oxoglutarate dependent dioxygenases, the core of the EctD structure consists of a double-stranded beta-helix forming the main portion of the active-site of the enzyme. The positioning of the iron ligand in the active-site of EctD is mediated by an evolutionarily conserved 2-His-1-carboxylate iron-binding motif. The side chains of the three residues forming this iron-binding site protrude into a deep cavity in the EctD structure that also harbours the 2-oxoglutarate co-substrate-binding site. Database searches revealed a widespread occurrence of EctD-type proteins in members of the Bacteria but only in a single representative of the Archaea, the marine crenarchaeon Nitrosopumilus maritimus. The EctD crystal structure reported here can serve as a template to guide further biochemical and structural studies of this biotechnologically interesting enzyme family. PMID:20498719

Reuter, Klaus; Pittelkow, Marco; Bursy, Jan; Heine, Andreas; Craan, Tobias; Bremer, Erhard

2010-01-01

232

A new method for Fourier analysis in ECG-gated cardiac blood pool emission computed tomography (ECT)  

SciTech Connect

An integrated technique for Fourier analysis in multigated blood pool ECT study has been developed. Following the administration of 15-20 mCi of Tc-99m RBC, ECG-gated cardiac blood pool data were acquired using an ECT system with dual opposed gamma cameras. Fundamental studies for data acquisition showed that acquisition time of 10 sec. for each projection, 14 divisions of one cardiac cycle and angular interval of 6/sup 0/ (60 projections over 360/sup 0/) were reasonable for clinical purpose. Total acquisition time was about 5 minutes under these conditions. Data were processed as follows: 1) Transaxial (TA) tomographic images in every phase of cardiac cycle were reconstructed by convolution algorithm; 2) TA images were rotated to construct sagittal (SAG) and short axial (S-A) oblique-angle tomography which are respectively parallel and perpendicular to the long axis of either of the ventricles; 3) Images covering the portion other than the purposed ventricle were eliminated from the series of SAG images in every phase of the cycle; 4) Images in the same phase were summed to construct a series of SAG and S-A planar images; and 5) Fourier analysis was made to construct phase and amplitude images. The advantages of this method are that the phase and amplitude images from arbitrary directions can be obtained, that the region of interest can be selected on a three dimensional basis, eliminating the overlapping activity of the other ventricle or neighbouring tissues, that the diseased areas can be easily and accurately localized even in small inferior wall myocardial infarction and that patient study can be finished within 5 minutes.

Ito, T.; Maeda, H.; Takeda, K.; Nakagawa, T.; Yamaguchi, N.; Konishi, T.; Ichikawa, T.

1984-01-01

233

The silicone breast implant controversy.  

PubMed

Feminists call it objectification. Consumer advocates call it victimization. Medical personnel call it augmentation. Women, implantation. Whatever the term, media hype and the increasing number of lawsuits against U.S. manufacturers of silicone breast implants has caused widespread concern among women and raised serious questions about the long term health risks and safety of breast implant devices. PMID:7780923

Guerette, P H

1995-02-01

234

The Nuclear Energy Advanced Modeling and Simulation Enabling Computational Technologies FY09 Report  

SciTech Connect

In this document we report on the status of the Nuclear Energy Advanced Modeling and Simulation (NEAMS) Enabling Computational Technologies (ECT) effort. In particular, we provide the context for ECT In the broader NEAMS program and describe the three pillars of the ECT effort, namely, (1) tools and libraries, (2) software quality assurance, and (3) computational facility (computers, storage, etc) needs. We report on our FY09 deliverables to determine the needs of the integrated performance and safety codes (IPSCs) in these three areas and lay out the general plan for software quality assurance to meet the requirements of DOE and the DOE Advanced Fuel Cycle Initiative (AFCI). We conclude with a brief description of our interactions with the Idaho National Laboratory computer center to determine what is needed to expand their role as a NEAMS user facility.

Diachin, L F; Garaizar, F X; Henson, V E; Pope, G

2009-10-12

235

Elementary Implantable Force Sensor  

PubMed Central

Implementing implantable sensors which are robust enough to maintain long term functionality inside the body remains a significant challenge. The ideal implantable sensing system is one which is simple and robust; free from batteries, telemetry, and complex electronics. We have developed an elementary implantable sensor for orthopaedic smart implants. The sensor requires no telemetry and no batteries to communicate wirelessly. It has no on-board signal conditioning electronics. The sensor itself has no electrical connections and thus does not require a hermetic package. The sensor is an elementary L-C resonator which can function as a simple force transducer by using a solid dielectric material of known stiffness between two parallel Archimedean coils. The operating characteristics of the sensors are predicted using a simplified, lumped circuit model. We have demonstrated sensor functionality both in air and in saline. Our preliminary data indicate that the sensor can be reasonably well modeled as a lumped circuit to predict its response to loading. PMID:24883335

Wachs, Rebecca A.; Ellstein, David; Drazan, John; Healey, Colleen P.; Uhl, Richard L.; Connor, Kenneth A.

2014-01-01

236

Implantable Impedance Plethysmography  

PubMed Central

We demonstrate by theory, as well as by ex vivo and in vivo measurements that impedance plethysmography, applied extravascularly directly on large arteries, is a viable method for monitoring various cardiovascular parameters, such as blood pressure, with high accuracy. The sensor is designed as an implant to monitor cardiac events and arteriosclerotic progression over the long term. PMID:25123467

Theodor, Michael; Ruh, Dominic; Ocker, Martin; Spether, Dominik; Forster, Katharina; Heilmann, Claudia; Beyersdorf, Friedhelm; Manoli, Yiannos; Zappe, Hans; Seifert, Andreas

2014-01-01

237

Implant-Supported Bridge  

MedlinePLUS

... can be built up using bone augmentation or grafting before the actual implant procedure begins. How Does It Work? In some cases, ... the space created by the missing tooth. Second procedure Month 4 or 5 (no bone grafting, lower jaw) Month 6 or 7 (no bone ...

238

Implantable Drug Dispenser  

NASA Technical Reports Server (NTRS)

Drugs such as insulin are injected as needed directly into bloodstream by compact implantable dispensing unit. Two vapor cavities produce opposing forces on drug-chamber diaphragm. Heaters in cavities allow control of direction and rate of motion of bellows. Dispensing capsule fitted with coil so batteries can be recharged by induction.

Collins, E. R. J.

1983-01-01

239

MR evaluation of breast implants.  

PubMed

This article describes the rationale and indications for breast implant-related magnetic resonance (MR) imaging, alone or in combination with breast cancer-related MR imaging. Basic silicone chemistry, implant styles, and normal appearances of breast implants are described. The various presentations of breast implant rupture are described, and a 4-point staging scheme for intracapsular rupture is reviewed. Finally, a discussion of what the reviewing physician needs to know is presented, both before breast implant MR examinations are requested and afterward, when results are reported. PMID:24792659

Middleton, Michael S

2014-05-01

240

Application of confocal laser microscopy for monitoring mesh implants in herniology  

SciTech Connect

The state of the surface of mesh implants and their encapsulation region in herniology is investigated by laser confocal microscopy. A correlation between the probability of developing relapses and the size and density of implant microdefects is experimentally shown. The applicability limits of differential reverse scattering for monitoring the post-operation state of implant and adjacent tissues are established based on model numerical experiments. (optical technologies in biophysics and medicine)

Zakharov, V P; Belokonev, V I; Bratchenko, I A; Timchenko, P E; Vavilov, A V; Volova, L T

2011-04-30

241

Ethical, Legal and Social Aspects of Brain-Implants Using Nano-Scale Materials and Techniques  

Microsoft Academic Search

Nanotechnology is an important platform technology which will add new features like improved biocompatibility, smaller size,\\u000a and more sophisticated electronics to neuro-implants improving their therapeutic potential. Especially in view of possible\\u000a advantages for patients, research and development of nanotechnologically improved neuro implants is a moral obligation. However,\\u000a the development of brain implants by itself touches many ethical, social and legal

Francois Berger; Sjef Gevers; Ludwig Siep; Klaus-Michael Weltring

2008-01-01

242

Current status of ion implantation equipment and techniques for semiconductor IC fabrication  

NASA Astrophysics Data System (ADS)

The status of the use of ion implantation for IC fabrication is described in terms of the history of ion implantation system sales, operating regions for beam currents and energies and new applications for advanced IC structures. Key aspects of process limiting effects such as charging, heating, channeling, particle contamination and uptime are discussed. New technologies such as MeV implantation, direct formation of buried dielectric layers, focused ion beams and advances in the use of computer controls are described.

Current, Michael I.

1985-01-01

243

Modeling of nanocluster formation by ion beam implantation  

NASA Astrophysics Data System (ADS)

A theoretical model was developed to investigate the mechanism of the formation of nanoclusters via ion beam implantation. The evolution of nanoclusters, including the nucleation and growth process known as Ostwald ripening, was rebuilt using numerical simulations. The effects of implantation parameters such as the ion energy, ion fluence, and temperature on the morphology of implanted microstructures were also studied through integration with the Monte Carlo Transport of Ions in Matter code calculation for the distribution profiles of implanted ions. With an appropriate ion fluence, a labyrinth-like nanostructure with broad size distributions of nanoclusters formed along the ion implantation range. In a latter stage, a buried layer of implanted impurity developed. With decreasing ion energy, the model predicted the formation of precipitates on the surface. These simulation results were fully consistent with many experimental observations. With increased temperature, the characteristic length and size of nanostructures would increase due to the high mobility. This theoretical model provides an efficient numerical approach for fully understanding the mechanism of the formation of nanoclusters, allowing for the design of ion beam experiments to form specific nanostructures through ion-implantation technology.

Li, Kun-Dar

2011-08-01

244

The Development of the Nucleus® Freedom™ Cochlear Implant System  

PubMed Central

Cochlear Limited (Cochlear™) released the fourth-generation cochlear implant system, Nucleus® Freedom™, in 2005. Freedom is based on 25 years of experience in cochlear implant research and development and incorporates advances in medicine, implantable materials, electronic technology, and sound coding. This article presents the development of Cochlear's implant systems, with an overview of the first 3 generations, and details of the Freedom system: the CI24RE receiver-stimulator, the Contour Advance™ electrode, the modular Freedom processor, the available speech coding strategies, the input processing options of SmartSound™ to improve the signal before coding as electrical signals, and the programming software. Preliminary results from multicenter studies with the Freedom system are reported, demonstrating better levels of performance compared with the previous systems. The final section presents the most recent implant reliability data, with the early findings at 18 months showing improved reliability of the Freedom implant compared with the earlier Nucleus 3 System. Also reported are some of the findings of Cochlear's collaborative research programs to improve recipient outcomes. Included are studies showing the benefits from bilateral implants, electroacoustic stimulation using an ipsilateral and/or contralateral hearing aid, advanced speech coding, and streamlined speech processor programming. PMID:17172547

Patrick, James F.; Busby, Peter A.; Gibson, Peter J.

2006-01-01

245

E ects of the Driving Force on the Composition of Natural Gas Hydrates  

E-print Network

-Pierre Monfort(2) and Jon S. Gudmundsson(3) (1) ABB O shore Systems, P.O. Box 443, 7501 Stj rdal, Norway (2) Norwegian University of Science and Technology, Department of Petroleum Engineering and Applied Geophysics- Platteeuw expressions were expanded by adding exponential terms which include the driving force and a system

Gudmundsson, Jon Steinar

246

Management of peri-implant mucositis and peri-implantitis.  

PubMed

Peri-implant diseases are defined as inflammatory lesions of the surrounding peri-implant tissues and include peri-implant mucositis (an inflammatory lesion limited to the surrounding mucosa of an implant) and peri-implantitis (an inflammatory lesion of the mucosa that affects the supporting bone with resulting loss of osseointegration). This review aims to describe the different approaches to manage both entities and to provide a critical evaluation of the evidence available on their efficacy. Therapy of peri-implant mucositis and nonsurgical therapy of peri-implantitis usually involve mechanical debridement of the implant surface using curettes, ultrasonic devices, air-abrasive devices or lasers, with or without the adjunctive use of local antibiotics or antiseptics. The efficacy of these therapies has been demonstrated for mucositis: controlled clinical trials show an improvement in clinical parameters, especially in bleeding on probing. For peri-implantitis, the results are limited, especially in terms of probing pocket-depth reduction. Surgical therapy of peri-implantitis is indicated when nonsurgical therapy fails to control the inflammatory changes. Selection of the surgical technique should be based on the characteristics of the peri-implant lesion. In the presence of deep circumferential and intrabony defects, surgical interventions should aim to provide thorough debridement, implant-surface decontamination and defect reconstruction. In the presence of defects without clear bony walls or with a predominant suprabony component, the aim of the surgical intervention should be the thorough debridement and the repositioning of the marginal mucosa to enable the patient to perform effective oral-hygiene practices, although this aim may compromise the esthetic result of the implant-supported restoration. PMID:25123773

Figuero, Elena; Graziani, Filippo; Sanz, Ignacio; Herrera, David; Sanz, Mariano

2014-10-01

247

The Aula EspaZio Gela and the Master of Space Science and Technology in the Universidad Del País Vasco (University of the Basque Country)  

ERIC Educational Resources Information Center

We present the Aula EspaZio Gela, a facility dedicated to teaching Space Science and Technology at the master and doctorate level at the University of the Basque Country (Spain), and to promoting the development of this field in both public and private sectors. The one-year master's degree in Space Science and Technology (60 ECTS (European…

Sánchez-Lavega, Agustín; Pérez-Hoyos, Santiago; Hueso, Ricardo; del Río-Gaztelurrutia, Teresa; Oleaga, Alberto

2014-01-01

248

SEM analysis of ion implanted SiC  

NASA Astrophysics Data System (ADS)

SiC is a material used in two future energy production technologies, firstly as a photovoltaic layer to harness the UV spectrum in high efficient power solar cells, and secondly as a diffusion barrier material for radioactive fission products in the fuel elements of the next generation of nuclear power plants. For both applications, there is an interest in the implantation of reactive and non-reactive ions into SiC and their effects on the properties of the SiC. In this study 360 keV Ag+, I+ and Xe+ ions were separately implanted into 6H-SiC and in polycrystalline SiC at various substrate temperatures. The implanted samples were also annealed in vacuum at temperatures ranging from 900 °C to 1600 °C for various times. In recent years, there had been significant advances in scanning electron microscopy (SEM) with the introduction of an in-lens detector combined with field emission electron guns. This allows defects in solids, such as radiation damage created by the implanted ions, to be detected with SEM. Cross-sectional SEM images of 6H-SiC wafers implanted with 360 keV Ag+ ions at room temperature and at 600 °C and then vacuum annealed at different temperatures revealed the implanted layers and their thicknesses. A similar result is shown of 360 keV I+ ions implanted at 600 °C into 6H-SiC and annealed at 1600 °C. The 6H-SiC is not amorphized but remained crystalline when implanting at 600 °C. There are differences in the microstructure of 6H-SiC implanted with silver at the two temperatures as well as with reactive iodine ions. Voids (bubbles) are created in the implanted layers into which the precipitation of silver and iodine can occur after annealing of the samples. The crystallinity of the substrate via implantation temperature caused differences in the distribution and size of the voids. Implantation of xenon ions in polycrystalline SiC at 350 °C does not amorphize the substrate as is the case with room temperature heavy ion bombardment. Subsequent annealing of the implanted polycrystalline samples leads to increased thermal etching effects such as grain boundary grooving. Damage due to channelling (or non-channelling) in the different crystallites resulted also in differences in thermal etching in the crystallites.

Malherbe, Johan B.; van der Berg, N. G.; Botha, A. J.; Friedland, E.; Hlatshwayo, T. T.; Kuhudzai, R. J.; Wendler, E.; Wesch, W.; Chakraborty, P.; da Silveira, E. F.

2013-11-01

249

Clinical trials of endosseous implants: issues in analysis and interpretation.  

PubMed

The majority of contemporary endosseous dental implant systems are based on designs and materials that, over the last three decades, have proved to be predictably reliable. With proper surgical and prosthetic protocols, rates of implant loss have been held to 15% or less over a 5-year period. This information was obtained largely through longitudinal descriptive studies, primarily aimed at obtaining implant survival rates under ideal clinical conditions, with strict inclusion and exclusion criteria for admitting patients into the studies. It is important to emphasize that under conditions of routine clinical practice, where patient selection may be more relaxed than in clinical trials and clinicians attempt to stretch the limits of current technology, the survival rates may not necessarily match those reported in the literature. Since "surviving" implants may exhibit characteristics likely to lead to eventual loss of the implant, for example severe osseous defects, such implants may not necessarily be considered successful. Successful implants should fulfill a list of other criteria considered essential for long-term survival. Differences in implant design preclude some of these criteria from being uniformly applied to all systems. There is a need to identify criteria for success that can be applied to the majority of implant systems. Implants that fail to meet these criteria should be considered failures. Since failure rates may include "failed" as well as "failing" ("ailing") implants, the two categories should be listed separately. From a practical standpoint, implant failures can be grouped into "early" failures, primarily the result of surgical and/or postoperative complications, and "late" failures that arise during and following the restorative phase. The ability of individual systems to achieve excellent success rates, despite some major differences in their design from other systems, suggests that some requirements, initially considered essential for success, may not be as critical as originally believed. Examples include the need for submerging implants during initial wound healing or the need for stress breaking devices. On the other hand, a basic requirement for implant success, such as primary stability at the time of insertion and following loading of the implant, may be the unifying principle behind the need for adequate bone volume and density, longer or wider implants, and the 3 to 6-month delay recommended before implants are placed in function. With relatively low failure rates, a large number of patients may have to be included in long-term clinical trials before a statistically significant association can be established between failure rates and potential contributing factors. For the same reasons, and to avoid type 2 errors, large populations may be needed to show that two systems have comparable success rates. Proving the superiority of one system over another may require fewer subjects. Given the overall low failure rate and the tendency of failures to cluster in individual subjects, failure rates could be markedly affected by the attrition of a few critical subjects. Additional research is needed to validate methods in current use for the clinical determination of osseointegration, and the diagnosis and treatment of occlusal trauma and microbial infections around implants. Also, more reliable methods are needed for the identification of the primary cause(s) of implant morbidity; i.e., infection or occlusal factors. PMID:9151563

Listgarten, M A

1997-03-01

250

Bone Substitutes for Peri-Implant Defects of Postextraction Implants  

PubMed Central

Placement of implants in fresh sockets is an alternative to try to reduce physiological resorption of alveolar ridge after tooth extraction. This surgery can be used to preserve the bone architecture and also accelerate the restorative procedure. However, the diastasis observed between bone and implant may influence osseointegration. So, autogenous bone graft and/or biomaterials have been used to fill this gap. Considering the importance of bone repair for treatment with implants placed immediately after tooth extraction, this study aimed to present a literature review about biomaterials surrounding immediate dental implants. The search included 56 articles published from 1969 to 2012. The results were based on data analysis and discussion. It was observed that implant fixation immediately after extraction is a reliable alternative to reduce the treatment length of prosthetic restoration. In general, the biomaterial should be used to increase bone/implant contact and enhance osseointegration. PMID:24454377

Santos, Pamela Leticia; Gulinelli, Jessica Lemos; Telles, Cristino da Silva; Betoni Junior, Walter; Chiacchio Buchignani, Vivian; Queiroz, Thallita Pereira

2013-01-01

251

Entertainment Television and Hearing Students' Attitudes Regarding the Pediatric Cochlear Implant  

Microsoft Academic Search

The cochlear implant, a bionic technology that restores sound sensation in some patients, has become ethically controversial in the 20 years since its introduction. This controversy recently has entered American entertainment culture, with the issue of pediatric implants emerging in episodes of popular TV programs. This pilot study examines the effects of one such TV episode on the attitudes of

Katrina R. Miller; Kathy Wheeler-Scruggs

2002-01-01

252

A review of guidelines for implant rehabilitation of the edentulous maxilla  

Microsoft Academic Search

This review suggests some guidelines and protocols for treatment of the edentulous maxilla with osseointegrated implants. Evidence-based treatment options are discussed with reference to risk assessment. Developing technologies applicable to diagnosis, clinical procedures, and laboratory techniques are also discussed. Osseointegrated implants are increasingly advocated as a treatment option for maxillary edentulism and in many situations are the treatment of choice.

Patrick J. Henry

2002-01-01

253

Chemical reactions of calcium phosphate implants after implantation in vivo  

Microsoft Academic Search

Sintered microporous cylinders of hydroxyapatite (OHA), tertiary calcium phosphate (ß-TCP and rhenanite (CaNaPO4) were implanted in the bone of the forehead of the domestic pig (Sus scrofa). Implants together with the surrounding bone were retrieved after 6 and 12 weeks. X-ray diffraction showed that OHA and ß-TCP maintain their crystal structure upon implantation. However, rhenanite is transformed completely into an

F. C. M. Driessens; M. M. A. Ramselaar; H. G. Schaeken; A. L. H. Stols; P. J. Mullem; J. R. Wijn

1992-01-01

254

Sub-meninges Implantation Reduces Immune Response to Neural Implants  

PubMed Central

Glial scar formation around neural interfaces inhibits their ability to acquire usable signals from the surrounding neurons. To improve neural recording performance, the inflammatory response and glial scarring must be minimized. Previous work has indicated that meningeally derived cells participate in the immune response, and it is possible that the meninges may grow down around the shank of a neural implant, contributing to the formation of the glial scar. This study examines whether the glial scar can be reduced by placing a neural probe completely below the meninges. Rats were implanted with sets of loose microwire implants placed either completely below the meninges or implanted conventionally with the upper end penetrating the meninges, but not attached to the skull. Histological analysis was performed 4 weeks following surgical implantation to evaluate the glial scar. Our results found that sub-meninges implants showed an average reduction in reactive astrocyte activity of 63% compared to trans-meninges implants. Microglial activity was also reduced for sub-meninges implants. These results suggest that techniques that isolate implants from the meninges offer the potential to reduce the encapsulation response which should improve chronic recording quality and stability. PMID:23370311

Markwardt, Neil T.; Stokol, Jodi; Rennaker, Robert L.

2013-01-01

255

The socially constructed breast: breast implants and the medical construction of need.  

PubMed Central

When silicone gel breast implants became the subject of a public health controversy in the early 1990s, the most pressing concern was safety. This paper looks at another, less publicized issue: the need for implants. Using a symbolic interactionist approach, the author explores the social construction of the need for implants by tracing the history of the 3 surgical procedures for which implants were used. Stakeholders in this history constructed need as legitimized individual desire, the form of which shifted with changes in the technological and social context. PMID:9702166

Jacobson, N

1998-01-01

256

The evolution of breast implants.  

PubMed

Breast augmentation remains one of the most common aesthetic procedures performed in the United States. Silicone implants have undergone an evolution with the availability of both fourth- and fifth-generation devices from the 3 leading manufacturers in the United States. This article explores the evolution of breast implants with special emphasis on the advancement of the silicone implants. Clinicians should strive to provide ongoing data and sound science to continue to improve clinical outcomes in the future. PMID:25057743

Maxwell, G Patrick; Gabriel, Allen

2014-07-01

257

Endometrium implantation and ectopic pregnancy  

Microsoft Academic Search

Embryo in uterine implantation is a complex and multifactor-related process and is a downstream and ideal point for woman\\u000a fertility control. Understanding the cellular and molecular mechanism of implantation is a prerequisite for development of\\u000a anti-implantation contraceptives. In spite of considerable accumulation of information from the laboratory animals that has\\u000a been achieved, it is difficult to generate such information in

Liu Yixun

2004-01-01

258

The e ect of router bu er size on the TCP performance K.E. Avrachenkov , U. Ayesta ;y E. Altman ;z , P.Nain , C. Barakat ;x  

E-print Network

the e#11;ect of the IP router bu#11;er size on the sending rate, the goodput and the latency of a TCP by #12;xed point approach is compared with the results obtained by NS simulator. Key words. TCP/IP, Fixed (FPA) developed in [1, 3]. The main idea behind FPA for the TCP/IP network is to combine a model

259

Combining peer?assessment with negotiated learning activities on a day?release undergraduate?level certificate course (ECTS level 3)  

Microsoft Academic Search

Peer?assessment was used within a negotiated curriculum in a module on training and development at ECTS level 3. The students on the programme were exclusively day?release and all had a major responsibility for the management and delivery of work?based training programmes. Analysis of student evaluations, supplemented by those of university assessors and the external examiner, showed that the learning on

Tim McMahon

2010-01-01

260

Domination game: e#ect of edge and vertexremoval Bostjan Bresar a,d Paul Dorbec b Sandi Klavzar c,a,d  

E-print Network

Domination game: e#ect of edge­ and vertex­removal BoŸstjan BreŸsar a,d Paul Dorbec b Sandi Klav and Mechanics, Ljubljana, Slovenia Abstract The domination game is played on a graph G by two players, named of vertices dominated before the move on it. Dominator's goal is that the game is finished as soon as possible

Klavzar, Sandi

261

Domination game: e#ect of edge and vertexremoval Bostjan Bresar a Paul Dorbec b Sandi Klavzar c,a Gasper Kosmrlj c  

E-print Network

Domination game: e#ect of edge� and vertex�removal Bo�stjan Bre�sar a Paul Dorbec b Sandi Klav sandi.klavzar@fmf.uni�lj.si gasper.kosmrlj@student.fmf.uni�lj.si Abstract The domination game is played is that the game is finished as soon as possible, while Staller wants the game to last as long as possible

Klavzar, Sandi

262

Immediate Direct-To-Implant Breast Reconstruction Using Anatomical Implants  

PubMed Central

Background In 2012, a new anatomic breast implant of form-stable silicone gel was introduced onto the Korean market. The intended use of this implant is in the area of aesthetic breast surgery, and many reports are promising. Thus far, however, there have been no reports on the use of this implant for breast reconstruction in Korea. We used this breast implant in breast reconstruction surgery and report our early experience. Methods From November 2012 to April 2013, the Natrelle Style 410 form-stable anatomically shaped cohesive silicone gel-filled breast implant was used in 31 breasts of 30 patients for implant breast reconstruction with an acellular dermal matrix. Patients were treated with skin-sparing mastectomies followed by immediate breast reconstruction. Results The mean breast resection volume was 240 mL (range, 83-540 mL). The mean size of the breast implants was 217 mL (range, 125-395 mL). Breast shape outcomes were considered acceptable. Infection and skin thinning occurred in one patient each, and hematoma and seroma did not occur. Three cases of wound dehiscence occurred, one requiring surgical intervention, while the others healed with conservative treatment in one month. Rippling did not occur. So far, complications such as capsular contracture and malrotation of breast implant have not yet arisen. Conclusions By using anatomic breast implants in breast reconstruction, we achieved satisfactory results with aesthetics better than those obtained with round breast implants. Therefore, we concluded that the anatomical implant is suitable for breast reconstruction. PMID:25276645

Kim, Sung-Eun; Jung, Dong-Woo; Chung, Kyu-Jin; Kim, Tae Gon; Kim, Yong-Ha; Lee, Soo Jung; Kang, Su Hwan; Choi, Jung Eun

2014-01-01

263

Short implants: A systematic review  

PubMed Central

Background: Short implants are manufactured for use in atrophic regions of the jaws. Although many studies report on short implants as ?10 mm length with considerable success, the literature regarding survival rate of ?7 mm is sparse. Purpose: The purpose of this study was to systematically evaluate the publications concerning short dental implants defined as an implant with a length of ?7 mm placed in the maxilla or in the mandible. Materials and Methods: A Medline and manual search was conducted to identify studies concerning short dental implants of length ?7 mm published between 1991 and 2011. The articles included in this study report data on implant length ?7 mm, such as demographic variables, implant type, location in jaws, observation time, prostheses and complications. Results: The 28 included studies represent one randomized controlled trial, 12 prospective studies and 10 retrospective studies. The survival rate of short implant was found to be increased from 80% to 90% gradually, with recent articles showing 100%. Conclusion: When severe atrophy of jaws was encountered, short and wide implants can be placed successfully. PMID:23162320

Karthikeyan, I.; Desai, Shrikar R.; Singh, Rika

2012-01-01

264

Implantable medical devices MRI safe.  

PubMed

Pacemakers, ICDs, neurostimulators like deep brain stimulator electrodes, spiral cord stimulators, insulin pumps, cochlear implants, retinal implants, hearing aids, electro cardio gram (ECG) leads, or devices in interventional MRI such as vascular guide wires or catheters are affected by MRI magnetic and electromagnetic fields. Design of MRI Safe medical devices requires computer modeling, bench testing, phantom testing, and animal studies. Implanted medical devices can be MRI unsafe, MRI conditional or MRI safe (see glossary). In the following paragraphs we will investigate how to design implanted medical devices MRI safe. PMID:23739365

Dal Molin, Renzo; Hecker, Bertrand

2013-01-01

265

A study of a respiratory related variation of muscle tone during the decrement of decerebrate tonicity in ECT  

PubMed Central

An oscillating decerebrate tonicity following the clonus phase in electroplexy was found to occur in the upper limbs, their tendon reflexes and the jaw; this increased with each expiration and decreased with inspiration. The times of these occurrences in the upper limbs were measured in groups where no anaesthesia, diazepam or methohexital were used. The mean times of their onset and end were related to other phenomena of ECT. The times of occurrence and duration of decerebrate tonicity were established and compared in the three cohorts. There was a definite relationship to the onset of respiratory rhythmicity in all three groups. The evidence for the existence of decerebrate tonicity and atonicity are discussed from experimental contributions and more recent clinical evidence of the clonus phase as an example of an oscillation between tonic and atonic decerebrate states. Further clinical and experimental data are discussed which show connections between the decerebrate state, cerebral and cerebellar functions, respiratory centres, brain-stem and gravity afferents during rest and locomotion. An explanation is offered that the oscillatory phenomena are probably a mechanism to aid respiration and motor efficiency. Images PMID:5551693

Tresise, P. C. C.

1971-01-01

266

MED-EL Cochlear Implants: State of the Art and a Glimpse Into the Future  

PubMed Central

Cochlear implantation is an accepted treatment method for adults and children with severe to profound hearing loss. Confidence in technology has led to changes in individuals who can receive a cochlear implant and changes in expected benefit with a cochlear implant. This article describes the research and development activities at MED-EL, which make possible the implementation of new speech-coding strategies as well as the application of acoustic and electric stimulation via a combined speech processor in MED-EL devices. Research on benefits from bilateral cochlear implantation and electric-acoustic stimulation are also reviewed. Finally, the potential of drug delivery systems is considered as a way to improve cochlear implant outcomes, and results from preliminary evaluations of a hybrid cochlear implant system with drug delivery capabilities are reported. PMID:17172548

Hochmair, Ingeborg; Nopp, Peter; Jolly, Claude; Schmidt, Marcus; Schößer, Hansjörg; Garnham, Carolyn; Anderson, Ilona

2006-01-01

267

Accuracy of computer-aided template-guided oral implant placement: a prospective clinical study  

PubMed Central

Purpose The aim of the present study was to evaluate the in vivo accuracy of flapless, computer-aided implant placement by comparing the three-dimensional (3D) position of planned and placed implants through an analysis of linear and angular deviations. Methods Implant position was virtually planned using 3D planning software based on the functional and aesthetic requirements of the final restorations. Computer-aided design/computer-assisted manufacture technology was used to transfer the virtual plan to the surgical environment. The 3D position of the planned and placed implants, in terms of the linear deviations of the implant head and apex and the angular deviations of the implant axis, was compared by overlapping the pre- and postoperative computed tomography scans using dedicated software. Results The comparison of 14 implants showed a mean linear deviation of the implant head of 0.56 mm (standard deviation [SD], 0.23), a mean linear deviation of the implant apex of 0.64 mm (SD, 0.29), and a mean angular deviation of the long axis of 2.42° (SD, 1.02). Conclusions In the present study, computer-aided flapless implant surgery seemed to provide several advantages to the clinicians as compared to the standard procedure; however, linear and angular deviations are to be expected. Therefore, accurate presurgical planning taking into account anatomical limitations and prosthetic demands is mandatory to ensure a predictable treatment, without incurring possible intra- and postoperative complications. Graphical Abstract PMID:25177520

2014-01-01

268

Development of Implantable Medical Devices: From an Engineering Perspective  

PubMed Central

From the first pacemaker implant in 1958, numerous engineering and medical activities for implantable medical device development have faced challenges in materials, battery power, functionality, electrical power consumption, size shrinkage, system delivery, and wireless communication. With explosive advances in scientific and engineering technology, many implantable medical devices such as the pacemaker, cochlear implant, and real-time blood pressure sensors have been developed and improved. This trend of progress in medical devices will continue because of the coming super-aged society, which will result in more consumers for the devices. The inner body is a special space filled with electrical, chemical, mechanical, and marine-salted reactions. Therefore, electrical connectivity and communication, corrosion, robustness, and hermeticity are key factors to be considered during the development stage. The main participants in the development stage are the user, the medical staff, and the engineer or technician. Thus, there are three different viewpoints in the development of implantable devices. In this review paper, considerations in the development of implantable medical devices will be presented from the viewpoint of an engineering mind. PMID:24143287

2013-01-01

269

Immediate loading and implant-bar overdenture.  

PubMed

Immediate loaded implants may be used with an implant-bar overdenture to provide fixed splinting. This is a relatively new system that provides for immediate implant placement and restoration. PMID:24787132

Chang, John; Millstein, Philip

2014-10-01

270

An Implantable MEMS Drug Delivery Device for Rapid Delivery in Ambulatory Emergency Care  

E-print Network

We introduce the first implantable drug delivery system based on MEMS (Micro-Electro-Mechanical-Systems) technology specifically designed as a platform for treatment in ambulatory emergency care. The device is named ...

Elman, Noel

271

Emergency delivery of Vasopressin from an implantable MEMS rapid drug delivery device  

E-print Network

An implantable rapid drug delivery device based on micro-electro-mechanical systems (MEMS) technology was designed, fabricated and validated for the in vivo rapid delivery of vasopressin in a rabbit model. In vitro ...

Ho Duc, Hong Linh, 1978-

2009-01-01

272

Implantable medical sensor system  

DOEpatents

An implantable chemical sensor system for medical applications is described which permits selective recognition of an analyte using an expandable biocompatible sensor, such as a polymer, that undergoes a dimensional change in the presence of the analyte. The expandable polymer is incorporated into an electronic circuit component that changes its properties (e.g., frequency) when the polymer changes dimension. As the circuit changes its characteristics, an external interrogator transmits a signal transdermally to the transducer, and the concentration of the analyte is determined from the measured changes in the circuit. This invention may be used for minimally invasive monitoring of blood glucose levels in diabetic patients.

Darrow, Christopher B. (Pleasanton, CA); Satcher, Jr., Joe H. (Modesto, CA); Lane, Stephen M. (Oakland, CA); Lee, Abraham P. (Walnut Creek, CA); Wang, Amy W. (Berkeley, CA)

2001-01-01

273

[A Roman orbital implant?].  

PubMed

During an excavation in Regensburg/Germany the skeleton of an approximately 20-year-old Roman man was found who was buried in the 3rd/4th century after Christ. A "stone" was found which fitted into the left orbit precisely. After a thorough investigation of the "stone" and with the ophthalmohistorical literature in mind an orbital "implant" as well as a petrified medical paste ("Kollyrium") could be ruled out almost with certainty. Possibly the "stone" served another medical purpose or was used for protection of the eye. PMID:23011607

Rohrbach, J M; Harbeck, M; Holzhauser, P; Tekeva-Rohrbach, C I; Mach, M; Codreanu-Windauer, S

2012-11-01

274

An Unusual Bone Loss Around Implants  

PubMed Central

Pre-implant disease is an inflammatory process that affects the surrounding tissues of a functional osseointegrated implant. It is usually the result of a disequilibrium between the micro-flora and the defense system. This case reports a 57-year-old man with unusual bone loss around dental implants. This was an unusual case of peri-implantitis that occurred only in the implants on one side of the mouth although they were all unloaded implants. PMID:24396359

Rokn, Amir Reza; Sajedinejad, Neda; Yousefyfakhr, Hosnieh; Badri, Samare

2013-01-01

275

Selective laser sintering of calcium phosphate materials for orthopedic implants  

Microsoft Academic Search

Two technologies, Solid Freeform Fabrication (SFF) and bioceramics are combined in this work to prepare bone replacement implants with complex geometry. SFF has emerged as a crucial technique for rapid prototyping in the last decade. Selective Laser Sintering (SLS) is one of the established SFF manufacturing processes that can build three-dimensional objects directly from computer models without part-specific tooling or

Goonhee Lee

1997-01-01

276

Sequential provisional implant prosthodontics therapy.  

PubMed

The fabrication and long-term use of first- and second-stage provisional implant prostheses is critical to create a favorable prognosis for function and esthetics of a fixed-implant supported prosthesis. The fixed metal and acrylic resin cemented first-stage prosthesis, as reviewed in Part I, is needed for prevention of adjacent and opposing tooth movement, pressure on the implant site as well as protection to avoid micromovement of the freshly placed implant body. The second-stage prosthesis, reviewed in Part II, should be used following implant uncovering and abutment installation. The patient wears this provisional prosthesis until maturation of the bone and healing of soft tissues. The second-stage provisional prosthesis is also a fail-safe mechanism for possible early implant failures and also can be used with late failures and/or for the necessity to repair the definitive prosthesis. In addition, the screw-retained provisional prosthesis is used if and when an implant requires removal or other implants are to be placed as in a sequential approach. The creation and use of both first- and second-stage provisional prostheses involve a restorative dentist, dental technician, surgeon, and patient to work as a team. If the dentist alone cannot do diagnosis and treatment planning, surgery, and laboratory techniques, he or she needs help by employing the expertise of a surgeon and a laboratory technician. This team approach is essential for optimum results. PMID:23220306

Zinner, Ira D; Markovits, Stanley; Jansen, Curtis E; Reid, Patrick E; Schnader, Yale E; Shapiro, Herbert J

2012-01-01

277

Changing Paradigms in Implant Dentistry  

Microsoft Academic Search

This review focuses on five paradigms of implant dentistry which have undergone considerable modifications in recent years. An attempt was made to select and include all the relevant citations of the past 10 years. These five paradigms document the debate in the clinical and scientific community and include the aspects of (1) smooth vs. rough implant surfaces, (2) submerged vs.

Giovanni E. Salvi; Niklaus P. Lang

2001-01-01

278

Porous metal for orthopedics implants  

PubMed Central

Summary Porous metal has been introduced to obtain biological fixation and improve longevity of orthopedic implants. The new generation of porous metal has intriguing characteristics that allows bone healing and high osteointegration of the metallic implants. This article gives an overview about biomaterials properties of the contemporary class of highly porous metals and about the clinical use in orthopaedic surgery. PMID:24133527

Matassi, Fabrizio; Botti, Alessandra; Sirleo, Luigi; Carulli, Christian; Innocenti, Massimo

2013-01-01

279

[Conservative femoral implants. Short stems].  

PubMed

Uncemented hip replacement matches the best results of classic cemented replacements. With the aim of preserving bone and soft tissue, implants with shorter stems and proximal metaphyseal support have been developed. Likewise, the lack of distal load should avoid cortical diaphyseal remodelling phenomena and the thigh pain of some cylindrical and wedge implants. The resurfacing implant, very popular as a conservative hip replacement in the young adult, has disadvantages associated with the fragility of the neck and with large head metal friction torque. Short stem hip replacement may be a reasonable alternative to classic implants and surface hip replacements. The different designs of conservative short stem implants are analysed, and are classified according to their morphology and biomechanical characteristics. Some medium term series show promising results. PMID:23177948

Valverde-Mordt, C; Valverde-Belda, D

2012-01-01

280

Engineering of implantable liver tissues.  

PubMed

In this chapter, from the engineering point of view, we introduce the results from our group and related research on three typical configurations of engineered liver tissues; cell sheet-based tissues, sheet-like macroporous scaffold-based tissues, and tissues based on special scaffolds that comprise a flow channel network. The former two do not necessitate in vitro prevascularization and are thus promising in actual human clinical trials for liver diseases that can be recovered by relatively smaller tissue mass. The third approach can implant a much larger mass but is still not yet feasible. In all cases, oxygen supply is the key engineering factor. For the first configuration, direct oxygen supply using an oxygen-permeable polydimethylsiloxane membrane enables various liver cells to exhibit distinct behaviors, complete double layers of mature hepatocytes and fibroblasts, spontaneous thick tissue formation of hepatocarcinoma cells and fetal hepatocytes. Actual oxygen concentration at the cell level can be strictly controlled in this culture system. Using this property, we found that initially low then subsequently high oxygen concentrations were favorable to growth and maturation of fetal cells. For the second configuration, combination of poly-L: -lactic acid 3D scaffolds and appropriate growth factor cocktails provides a suitable microenvironment for the maturation of cells in vitro but the cell growth is limited to a certain distance from the inner surfaces of the macropores. However, implantation to the mesentery leaves of animals allows the cells again to proliferate and pack the remaining spaces of the macroporous structure, suggesting the high feasibility of 3D culture of hepatocyte progenitors for liver tissue-based therapies. For the third configuration, we proposed a design criterion concerning the dimensions of flow channels based on oxygen diffusion and consumption around the channel. Due to the current limitation in the resolution of 3D microfabrication processes, final cell densities were less than one-tenth of those of in vivo liver tissues; cells preferentially grew along the surfaces of the channels and this fact suggested the necessity of improved 3D fabrication technologies with higher resolution. In any case, suitable oxygen supply, meeting the cellular demand at physiological concentrations, was the most important factor that should be considered in engineering liver tissues. This enables cells to utilize aerobic respiration that produces almost 20 times more ATP from the same glucose consumption than anaerobic respiration (glycolysis). This also allows the cells to exhibit their maximum reorganization capability that cannot be observed in conventional anaerobic conditions. PMID:22167650

Sakai, Yasuyuki; Nishikawa, M; Evenou, F; Hamon, M; Huang, H; Montagne, K P; Kojima, N; Fujii, T; Niino, T

2012-01-01

281

Speech Production Intelligibility of Early Implanted Pediatric Cochlear Implant Users  

PubMed Central

Objectives To investigate the influence of age, and age at implantation, on speech production intelligibility in prelingually deaf pediatric cochlear implant recipients. Methods Forty prelingually, profoundly deaf children who received cochlear implants between 8 and 40 months of age. Their age at testing ranged between 2.5 – 18 years. Children were recorded repeating the ten sentences in the Beginner’s Intelligibility Test. These recordings were played back to normal-hearing listeners who were unfamiliar with deaf speech and who were instructed to write down what they heard. They also rated each subject for the intelligibility of their speech production on a 5-point rating scale. The main outcome measures were the percentage of target words correctly transcribed, and the intelligibility ratings, in both cases averaged across three normal-hearing listeners. Results The data showed a strong effect of age at testing, with older children being more intelligible. This effect was particularly pronounced for children implanted in the first 24 months of life, all of whom had speech production intelligibility scores of 80% or higher when they were tested at age 5.5 years or older. This was true for only five out of nine children implanted at age 25 to 36 months. Conclusions Profoundly deaf children who receive cochlear implants in the first two years of life produce highly intelligible speech before age 6. This is also true for most, but not all children implanted in their third year. PMID:20472308

Habib, Mirette G.; Waltzman, Susan B.; Tajudeen, Bobby; Svirsky, Mario A.

2010-01-01

282

Kelch-like ECT2-interacting protein KLEIP regulates late-stage pulmonary maturation via Hif-2? in mice.  

PubMed

Respiratory distress syndrome (RDS) caused by preterm delivery is a major clinical problem with limited mechanistic insight. Late-stage embryonic lung development is driven by hypoxia and the hypoxia-inducible transcription factors Hif-1? and Hif-2?, which act as important regulators for lung development. Expression of the BTB-and kelch-domain-containing (BTB-kelch) protein KLEIP (Kelch-like ECT2-interacting protein; also named Klhl20) is controlled by two hypoxia response elements, and KLEIP regulates stabilization and transcriptional activation of Hif-2?. Based on the available data, we hypothesized an essential role for KLEIP in murine lung development and function. Therefore, we have performed a functional, histological, mechanistic and interventional study in embryonic and neonatal KLEIP(-/-) mice. Here, we show that about half of the KLEIP(-/-) neonates die due to respiratory failure that is caused by insufficient aeration, reduced septal thinning, reduced glycogenolysis, type II pneumocyte immaturity and reduced surfactant production. Expression analyses in embryonic day (E) 18.5 lungs identified KLEIP in lung capillaries, and showed strongly reduced mRNA and protein levels for Hif-2? and VEGF; such reduced levels are associated with embryonic endothelial cell apoptosis and lung bleedings. Betamethasone injection in pregnant females prevented respiratory failure in KLEIP(-/-) neonates, normalized lung maturation, vascularization, aeration and function, and increased neonatal Hif-2? expression. Thus, the experimental study shows that respiratory failure in KLEIP(-/-) neonates is determined by insufficient angiocrine Hif-2?-VEGF signaling and that betamethasone activates this newly identified signaling cascade in late-stage embryonic lung development. PMID:24785085

Woik, Nicole; Dietz, Christian T; Schäker, Kathrin; Kroll, Jens

2014-06-01

283

Kelch-like ECT2-interacting protein KLEIP regulates late-stage pulmonary maturation via Hif-2? in mice  

PubMed Central

Respiratory distress syndrome (RDS) caused by preterm delivery is a major clinical problem with limited mechanistic insight. Late-stage embryonic lung development is driven by hypoxia and the hypoxia-inducible transcription factors Hif-1? and Hif-2?, which act as important regulators for lung development. Expression of the BTB-and kelch-domain-containing (BTB-kelch) protein KLEIP (Kelch-like ECT2-interacting protein; also named Klhl20) is controlled by two hypoxia response elements, and KLEIP regulates stabilization and transcriptional activation of Hif-2?. Based on the available data, we hypothesized an essential role for KLEIP in murine lung development and function. Therefore, we have performed a functional, histological, mechanistic and interventional study in embryonic and neonatal KLEIP?/? mice. Here, we show that about half of the KLEIP?/? neonates die due to respiratory failure that is caused by insufficient aeration, reduced septal thinning, reduced glycogenolysis, type II pneumocyte immaturity and reduced surfactant production. Expression analyses in embryonic day (E) 18.5 lungs identified KLEIP in lung capillaries, and showed strongly reduced mRNA and protein levels for Hif-2? and VEGF; such reduced levels are associated with embryonic endothelial cell apoptosis and lung bleedings. Betamethasone injection in pregnant females prevented respiratory failure in KLEIP?/? neonates, normalized lung maturation, vascularization, aeration and function, and increased neonatal Hif-2? expression. Thus, the experimental study shows that respiratory failure in KLEIP?/? neonates is determined by insufficient angiocrine Hif-2?–VEGF signaling and that betamethasone activates this newly identified signaling cascade in late-stage embryonic lung development. PMID:24785085

Woik, Nicole; Dietz, Christian T.; Schaker, Kathrin; Kroll, Jens

2014-01-01

284

A Retrospective Analysis of Ruptured Breast Implants  

PubMed Central

Background Rupture is an important complication of breast implants. Before cohesive gel silicone implants, rupture rates of both saline and silicone breast implants were over 10%. Through an analysis of ruptured implants, we can determine the various factors related to ruptured implants. Methods We performed a retrospective review of 72 implants that were removed for implant rupture between 2005 and 2014 at a single institution. The following data were collected: type of implants (saline or silicone), duration of implantation, type of implant shell, degree of capsular contracture, associated symptoms, cause of rupture, diagnostic tools, and management. Results Forty-five Saline implants and 27 silicone implants were used. Rupture was diagnosed at a mean of 5.6 and 12 years after insertion of saline and silicone implants, respectively. There was no association between shell type and risk of rupture. Spontaneous was the most common reason for the rupture. Rupture management was implant change (39 case), microfat graft (2 case), removal only (14 case), and follow-up loss (17 case). Conclusions Saline implants have a shorter average duration of rupture, but diagnosis is easier and safer, leading to fewer complications. Previous-generation silicone implants required frequent follow-up observation, and it is recommended that they be changed to a cohesive gel implant before hidden rupture occurs.

Baek, Woo Yeol; Lew, Dae Hyun

2014-01-01

285

Ion implantation synthesized copper oxide-based resistive memory devices  

NASA Astrophysics Data System (ADS)

Copper oxide resistive memory layers have been synthesized by ion implantation. Devices fabricated from off-stoichiometric Cu2O exhibited unipolar switching in forward/reverse bias without a forming voltage. The on-state conduction of these devices is likely dominated by a metallic filament, which ruptures via Joule heating to transition the device to the high resistance off-state. Technology scaling was achieved by oxygen implanting copper filled vias. The resulting via-based memory devices exhibited unipolar resistive switching down to 48 nm in diameter.

Bishop, S. M.; Bakhru, H.; Novak, S. W.; Briggs, B. D.; Matyi, R. J.; Cady, N. C.

2011-11-01

286

Transcatheter aortic valve implantation.  

PubMed

Transcatheter aortic valve implantation (TAVI) was introduced experimentally in 1989, based on a newly developed heart valve prosthesis - the stentvalve. The valve was invented by a Danish cardiologist named Henning Rud Andersen. The new valve was revolutionary. It was foldable and could be inserted via a catheter through an artery in the groin, without the need for heart lung machine. This allowed for a new valve implantation technique, much less invasive than conventional surgical aortic valve replacement (SAVR). Surgical aortic valve replacement is safe and improves symptoms along with survival. However, up to 1/3 of patients with aortic valve stenosis cannot complete the procedure due to frailty. The catheter technique was hoped to provide a new treatment option for these patients. The first human case was in 2002, but more widespread clinical use did not begin until 2006-2010. Today, in 2011, more than 40,000 valves have been implanted worldwide. Initially, because of the experimental character of the procedure, TAVI was reserved for patients who could not undergo SAVR due to high risk. The results in this group of patients were promising. The procedural safety was acceptable, and the patients experienced significant improvements in their symptoms. Three of the papers in this PhD-thesis are based on the outcome of TAVI at Skejby Hospital, in this high-risk population [I, II and IV]. Along with other international publications, they support TAVI as being superior to standard medical treatment, despite a high risk of prosthetic regurgitation. These results only apply to high-risk patients, who cannot undergo SAVR. The main purpose of this PhD study has been to investigate the quality of TAVI compared to SAVR, in order to define the indications for this new procedure. The article attached [V] describes a prospective clinical randomised controlled trial, between TAVI to SAVR in surgically amenable patients over 75 years of age with isolated aortic valve stenosis. The study was terminated prematurely, as patients undergoing TAVI showed a statistically non-significant trend towards more complications than SAVR patients. Although non-significant the study was closed for ethical reasons. At present, scientific evidence supports TAVI as being superior to standard medical treatment, in patients who cannot undergo SAVR due to high- predicted risk. However, in patients who are surgically amenable, current publications suggest that TAVI using presently available devices is not competitive to SAVR, with regards to procedural safety and outcome. PMID:23290293

Nielsen, Hans Henrik Møller

2012-12-01

287

Ultraviolet photofunctionalization of titanium implants.  

PubMed

In the face of growing demands and challenges in implant therapy, implant surfaces with improved biologic capabilities are required. This review paper summarizes the findings of recent in vitro and in vivo studies related to ultraviolet (UV) photofunctionalization of titanium. UV photofunctionalization is defined as an overall phenomenon of modification of titanium surfaces occuring after UV treatment, including the alteration of physicochemical properties and the enhancement of biologic capabilities. Bone morphogenesis around UV-treated titanium implants is distinctly improved compared with that seen around untreated control implants, leading to rapid and complete establishment of osseointegration with nearly 100% bone-to-implant contact in an animal model, as opposed to less than 55% for untreated implants. A series of in vitro studies demonstrated considerable enhancement of attachment, retention, and subsequent functional cascades of osteogenic cells derived from animals and humans after UV treatment. UV treatment converts titanium surfaces from hydrophobic to superhydrophilic and removes unavoidably contaminated hydrocarbons. UV-treated titanium surfaces also manifest a unique electrostatic status and act as direct cell attractants without the aid of ionic and organic bridges, which imparts a novel physicochemical functionality to titanium, which has long been understood as a bioinert material. UV treatment is simple and low in cost, and it has been proven effective for all types of titanium surfaces tested. These data suggest that UV photofunctionalization can be a novel, effective measure to improve implant therapy in the dental and orthopedic fields. Future research will focus on validating these findings in clinical studies. PMID:24451893

Ogawa, Takahiro

2014-01-01

288

Ion implantation for high performance III-V JFETS and HFETS  

SciTech Connect

Ion implantation has been an enabling technology for realizing many high performance electronic devices in III-V semiconductor materials. We report on advances in ion implantation processing for GaAs JFETs (joint field effect transistors), AlGaAs/GaAs HFETs (heterostructure field effect transistors), and InGaP or InAlP-barrier HFETs. The GaAs JFET has required the development of shallow p-type implants using Zn or Cd with junction depths down to 35 nm after the activation anneal. Implant activation and ionization issues for AlGaAs are reported along with those for InGaP and InAlP. A comprehensive treatment of Si-implant doping of AlGaAs is given based on donor ionization energies and conduction band density-of-states dependence on Al-composition. Si and Si+P implants in InGaP are shown to achieve higher electron concentrations than for similar implants in AlGaAs due to absence of the deep donor level. An optimized P co- implantation scheme in InGaP is shown to increase the implanted donor saturation level by 65%.

Zolper, J.C.; Baca, A.G.; Sherwin, M.E.; Klem, J.F.

1996-06-01

289

Beyond cochlear implants: awakening the deafened brain  

Microsoft Academic Search

Cochlear implants have provided hearing to more than 120,000 deaf people. Recent surgical developments include direct electrical stimulation of the brain, bilateral implants and implantation in children less than 1 year old. However, research is beginning to refocus on the role of the brain in providing benefits to implant users. The auditory system is able to use the highly impoverished

Robert V Shannon; David R Moore

2009-01-01

290

Short Dental Implants: A Systematic Review  

Microsoft Academic Search

Growing evidence has suggested the utility of short dental implants for oral reconstructive procedures in clinical situations of limited vertical bone height. The aim of this review was to systematically evaluate clinical studies of implants < 10 mm in length, to determine short implant-supported prosthesis success in the atrophic jaw. Implant survival, incidence of biological and biomechanical complications, and radiographic

S. Annibali; M. P. Cristalli; D. Dell’Aquila; I. Bignozzi; G. La Monaca; A. Pilloni

2012-01-01

291

Pediatric cochlear implantation: an update.  

PubMed

Deafness in pediatric age can adversely impact language acquisition as well as educational and social-emotional development. Once diagnosed, hearing loss should be rehabilitated early; the goal is to provide the child with maximum access to the acoustic features of speech within a listening range that is safe and comfortable. In presence of severe to profound deafness, benefit from auditory amplification cannot be enough to allow a proper language development. Cochlear implants are partially implantable electronic devices designed to provide profoundly deafened patients with hearing sensitivity within the speech range. Since their introduction more than 30 years ago, cochlear implants have improved their performance to the extent that are now considered to be standard of care in the treatment of children with severe to profound deafness. Over the years patient candidacy has been expanded and the criteria for implantation continue to evolve within the paediatric population. The minimum age for implantation has progressively reduced; it has been recognized that implantation at a very early age (12-18 months) provides children with the best outcomes, taking advantage of sensitive periods of auditory development. Bilateral implantation offers a better sound localization, as well as a superior ability to understand speech in noisy environments than unilateral cochlear implant. Deafened children with special clinical situations, including inner ear malformation, cochlear nerve deficiency, cochlear ossification, and additional disabilities can be successfully treated, even thogh they require an individualized candidacy evaluation and a complex post-implantation rehabilitation. Benefits from cochlear implantation include not only better abilities to hear and to develop speech and language skills, but also improved academic attainment, improved quality of life, and better employment status. Cochlear implants permit deaf people to hear, but they have a long way to go before their performance being comparable to that of the intact human ear; researchers are looking for more sophisticated speech processing strategies as well as a more efficient coupling between the electrodes and the cochlear nerve with the goal of dramatically improving the quality of sound of the next generation of implants. PMID:25179127

Vincenti, Vincenzo; Bacciu, Andrea; Guida, Maurizio; Marra, Francesca; Bertoldi, Barbara; Bacciu, Salvatore; Pasanisi, Enrico

2014-01-01

292

Cochlear implantation in psoriasis patients.  

PubMed

Cochlear implantation has become a safe and effective method for the auditory rehabilitation of severe to profound sensorineural hearing loss. Flap problems are the commonest of the surgical complications [Axon PR, Mawman DJ, Upile T, Ramsden RT. Cochlear implantation in the presence of chronic suppurative otitis media. J Laryngol Otology 1997;111:228-32] and the risk increases further when associated with medical conditions predisposing to infection. We present two patients with psoriasis who underwent cochlear implant surgery, discussing the risk of surgical site infection and treatment options to minimise infection. PMID:17055206

Basavaraj, Sreeshyla; Wardrop, Peter; Sivaji, Nagaraj; Shanks, Mary; Allen, Agnes A

2007-06-01

293

Wireless microsensor network solutions for neurological implantable devices  

NASA Astrophysics Data System (ADS)

The design and development of wireless mocrosensor network systems for the treatment of many degenerative as well as traumatic neurological disorders is presented in this paper. Due to the advances in micro and nano sensors and wireless systems, the biomedical sensors have the potential to revolutionize many areas in healthcare systems. The integration of nanodevices with neurons that are in communication with smart microsensor systems has great potential in the treatment of many neurodegenerative brain disorders. It is well established that patients suffering from either Parkinson"s disease (PD) or Epilepsy have benefited from the advantages of implantable devices in the neural pathways of the brain to alter the undesired signals thus restoring proper function. In addition, implantable devices have successfully blocked pain signals and controlled various pelvic muscles in patients with urinary and fecal incontinence. Even though the existing technology has made a tremendous impact on controlling the deleterious effects of disease, it is still in its infancy. This paper presents solutions of many problems of today's implantable and neural-electronic interface devices by combining nanowires and microelectronics with BioMEMS and applying them at cellular level for the development of a total wireless feedback control system. The only device that will actually be implanted in this research is the electrodes. All necessary controllers will be housed in accessories that are outside the body that communicate with the implanted electrodes through tiny inductively-coupled antennas. A Parkinson disease patient can just wear a hat-system close to the implantable neural probe so that the patient is free to move around, while the sensors continually monitor, record, transmit all vital information to health care specialist. In the event of a problem, the system provides an early warning to the patient while they are still mobile thus providing them the opportunity to react and trigger the feed back system or contact a point-of-care office that can remotely control the implantable system. The remote monitoring technology can be adaptable to EEG monitoring of children with epilepsy, implantable cardioverters/defibrillators, pacemakers, chronic pain management systems, treatment for sleep disorders, patients with implantable devices for diabetes. In addition, the development of a wireless neural electronics interface to detect, transmit and analyze neural signals could help patients with spinal injuries to regain some semblance of mobile activity.

Abraham, Jose K.; Whitchurch, Ashwin; Varadan, Vijay K.

2005-05-01

294

Soft Cochlear Implantation: Rationale for the Surgical Approach  

PubMed Central

Recent advances in cochlear implant technology have focused renewed attention on the preservation of residual hearing. The focus on preservation of residual hearing is driven by the concept of electroacoustic stimulation. This option depends on the insertion of a short cochlear implant electrode into the basal region of the cochlea while preserving native function in the apical region. The desire to preserve residual hearing has led to the development of the soft-surgery cochlear implantation technique. Here, the authors evaluate its various components. Avoiding entry of blood into the cochlea and the use of hyaluronate seem to be reasonably supported, whereas the use of topical steroids is unlikely to be beneficial. The site of entry into the cochlea, the use of contoured or straight devices, and the depth of insertion are also evaluated. The authors highlight the importance of systematic recording of outcomes and surgical events. PMID:19447766

Friedland, David R.; Runge-Samuelson, Christina

2009-01-01

295

Ion-implanted laser annealed silicon solar cells  

NASA Technical Reports Server (NTRS)

Development of low cost solar cells fabrication technology is being sponsored by NASA JPL as part of the Low Cost Solar Array Project (LSA). In conformance to Project requirements ion implantation and laser annealing were evaluated as junction formation techniques offering low cost-high throughput potential. Properties of cells fabricated utilizing this technology were analyzed by electrical, transmission electron microscopy, Rutherford backscattering and secondary ion mass spectrometry techniques. Tests indicated the laser annealed substrates to be damage free and electrically active. Similar analysis of ion implanted furnace annealed substrates revealed the presence of residual defects in the form of dislocation lines and loops with substantial impurity redistribution evident for some anneal temperature/time regimes. Fabricated laser annealed cells exhibited improved spectral response and conversion efficiency in comparison to furnace annealed cells. An economic projection for LSA indicates a potential for considerable savings from laser annealing technology.

Katzeff, J. S.

1980-01-01

296

The design and fabrication of fiber-reinforced implant prostheses.  

PubMed

The use of fiber composite technology in the creation of metal-free implant prostheses may solve many of the problems associated with a metal alloy substructure such as corrosion, toxicity, complexity of fabrication, high cost, and esthetic limitations. Laboratory and clinical research evaluating glass fiber-reinforced composite prostheses used to restore and replace teeth has shown that these materials exhibit excellent mechanical properties and can form a chemical bond to resin-based veneer materials such as those used in the fabrication of certain types of implant prostheses. Two different designs of fiber-reinforced composite implant prostheses have been developed and placed in human subjects. One design (screw-retained, retrievable prosthesis) is used with implant abutments that allow for screw-retained prostheses; the other design is used with abutments that retain prostheses with a luting material. Both designs are described in this article. The prostheses have functioned well in a small group of preliminary subjects, but clinical trials with larger subject populations are needed to more completely evaluate the potential of fiber-reinforced composites in implant prosthodontics. PMID:12447224

Freilich, Martin A; Duncan, Jacqueline P; Alarcon, E Karina; Eckrote, Kimberly A; Goldberg, A Jon

2002-10-01

297

The Esteem System: a totally implantable hearing device.  

PubMed

The Esteem totally implantable active middle ear implant is a new technology to augment hearing in patients suffering from moderate-to-severe and severe sensorineural hearing loss. In contrast to conventional (acoustic) hearing aids, the system uses two piezoelectric transducers (PZTs). PZTs are used as the sensor and driver to replace the function of the middle ear. Sound is received via a PZT sensor that picks up eardrum vibrations, following the piezoelectric principle, and transforms them into an electric signal. This signal is filtered, modified, amplified and transferred to a PZT driver, which mechanically drives the stapes and thereby the inner ear. The sound processor also contains a power source, which is an implantable lithium iodide battery. All components of the hearing restoration system are totally implantable to offer good sound fidelity and reduce hearing aid stigma caused by the visibility of conventional and semi-implantable hearing systems. Our experience shows that this system can provide considerable benefit to patients with sensorineural hearing loss. PMID:20610915

Maurer, J; Savvas, E

2010-01-01

298

Improvement of the MR imaging behavior of vascular implants.  

PubMed

Vascular implants can cause significant MR image artifacts due to the material (susceptibility artifact) or the electromagnetic characteristics (RF artifact). These artifacts are caused by the distortion of the magnetic field and interferences with the radio frequency (RF) waves of the MR imaging process. Void or complete vanishing of signals occurs in close proximity or inside implants. The artifacts can be minimized by using a material with low magnetic susceptibility and a design of the implant which avoids electrical conductive loops. But not all designs can be made loop-free and non conductive. A resonant circuit tuned to the Larmor frequency of the MR tomography overcomes the RF artifact and thus improves the visualization of the implant lumen. The paper reviews the state-of-the-art technology of the MR-signal improvement in implants lumen, with particular regard to the use of resonant circuits such as stents or Vena Cava Filter (VCF), with resonators in 1.0 Tesla and 1.5Tesla MRT. PMID:16754191

Immel, Erwin; Melzer, Andreas

2006-01-01

299

Subcutaneous Implantable Cardioverter-Defibrillator  

MedlinePLUS

... the SICD. The SICD lacks remote monitoring capabilities. Battery Life Device battery replacement is necessary for all patients with implanted devices. The SICD battery life is not as long as that of ...

300

Nanosurface - the future of implants.  

PubMed

Nanotechnology is a relatively newer field of science that is finding enormous scope in the dental & medical science. Use of endosseous dental implant surfaces having nano-scale topography is fast becoming part of modern implantology. The purpose of this review is to discuss and understand the role of nanoscale surface modification of titanium materials for the purpose of improving various phases of implantology including osseointegration. Nanotechnology equips bioengineers with newer ways of interacting with relevant biological processes. On the other hand, the field of nanotechnology provides means of understanding and achieving cell specific functions. An understanding of the role of nano-topography leads to the significant osseointegration modulations by nanoscale modification of the implants surface. Use of nanotechnology to modify the topography of titanium endosseous implant can drastically improve cellular and tissue responses that may benefit osseointegration and dental implant procedures. PMID:24995264

Thakral, Gk; Thakral, Rashmi; Sharma, Neeraj; Seth, Jyotsana; Vashisht, Pallavi

2014-05-01

301

ANTIARRHYTHMICS VERSUS IMPLANTABLE DEFIBRILLATORS (AVID)  

EPA Science Inventory

Evaluates whether use of an implantable cardiac defibrillator (ICD) results in reduction in total mortality, when compared with conventional pharmacological therapy, in patients resuscitated from sudden cardiac death who are otherwise at very high risk of mortality from arrhythmi...

302

Nanosurface - The Future of Implants  

PubMed Central

Nanotechnology is a relatively newer field of science that is finding enormous scope in the dental & medical science. Use of endosseous dental implant surfaces having nano-scale topography is fast becoming part of modern implantology. The purpose of this review is to discuss and understand the role of nanoscale surface modification of titanium materials for the purpose of improving various phases of implantology including osseointegration. Nanotechnology equips bioengineers with newer ways of interacting with relevant biological processes. On the other hand, the field of nanotechnology provides means of understanding and achieving cell specific functions. An understanding of the role of nano-topography leads to the significant osseointegration modulations by nanoscale modification of the implants surface. Use of nanotechnology to modify the topography of titanium endosseous implant can drastically improve cellular and tissue responses that may benefit osseointegration and dental implant procedures. PMID:24995264

Thakral, Rashmi; Sharma, Neeraj; Seth, Jyotsana; Vashisht, Pallavi

2014-01-01

303

The EŠects of Kampo-Formulation and the Constituting Crude Drugs, Prescribed for the Treatment of Peptic Ulcer on H,K-ATPase Activity  

Microsoft Academic Search

We studied the eŠects of 17 kinds of Kampo-formulations prescribed for the treatment of peptic ulcer on H,K-AT- Pase activity. The activity was strongly inhibited by San-o-shashin-to (?????,IC50=82 mg\\/ml), Bukuryo-in (?? ?,IC50=110 mg\\/ml), Shakuyaku-kanzo-to (?????,IC50=170 mg\\/ml), Hange-koboku-to (?????,IC50= 290 mg\\/ml), Dai-saiko-to (????,IC50=340 mg\\/ml), Irei-san (???,IC50=380 mg\\/ml) than other Kampo-formu- lations. Among the 17 kinds of crude drugs contained in these

Kanako SATOH

304

Implant stategies for Littlefield Feedyard  

E-print Network

. Economic Impact of Different Price Spreads on Carcass Value 7. Economic Impact of Lower Actual Percentages of Choice Carcasses 8. Hypothetical Choice and Select Spread Scenario 9. Projection Table of Days on Feed (For Steers and Heifers) 10. Implant... to remove some of the risk &om Friona Industries. If this were to occur, the carcass quality would become the primary factor, and feed/gain performance a secondary role, to selecting an implant program. In this scenario, advantages of using an aggressive...

Turner, John Sutton

2012-06-07

305

Muscular contraction by implanted stimulators  

Microsoft Academic Search

Implanted stimulators have been used at a number of sites within the body, which include (apart from the heart) the bladder,\\u000a rectum and urethra. A small radio-frequency generator is commonly used externally, coupling to an implanted pick-up coil and\\u000a rectifying system. The design of both the electronic circuitry and the electrode geometry is dependent on the physiology and\\u000a anatomy of

P. G. Lale

1966-01-01

306

Ceramic-Coated Implant Systems  

Microsoft Academic Search

Practitioners have used hydroxyapatite-coated (HA-coated) endosseous and subperiosteal implants in various forms for many years. These have included root forms in both screw and cylindrical shapes, blades, and subperiosteals. The clinical predictability remains controversial and subject to claims and counterclaims. The early days of dental implantology involving root-form implants recommended their placement in fully edentulous cases only, and anterior to

Roland M. Meffert

1999-01-01

307

Auditory Midbrain Implant: A Review  

PubMed Central

The auditory midbrain implant (AMI) is a new hearing prosthesis designed for stimulation of the inferior colliculus in deaf patients who cannot sufficiently benefit from cochlear implants. The authors have begun clinical trials in which five patients have been implanted with a single shank AMI array (20 electrodes). The goal of this review is to summarize the development and research that has led to the translation of the AMI from a concept into the first patients. This study presents the rationale and design concept for the AMI as well a summary of the animal safety and feasibility studies that were required for clinical approval. The authors also present the initial surgical, psychophysical, and speech results from the first three implanted patients. Overall, the results have been encouraging in terms of the safety and functionality of the implant. All patients obtain improvements in hearing capabilities on a daily basis. However, performance varies dramatically across patients depending on the implant location within the midbrain with the best performer still not able to achieve open set speech perception without lip-reading cues. Stimulation of the auditory midbrain provides a wide range of level, spectral, and temporal cues, all of which are important for speech understanding, but they do not appear to sufficiently fuse together to enable open set speech perception with the currently used stimulation strategies. Finally, several issues and hypotheses for why current patients obtain limited speech perception along with several feasible solutions for improving AMI implementation are presented. PMID:19762428

Lim, Hubert H.; Lenarz, Minoo; Lenarz, Thomas

2009-01-01

308

Scleroderma and silicone breast implants.  

PubMed Central

Scleroderma, a systemic connective tissue disease, is relatively rare. Case reports of women with silicone breast implants who have developed scleroderma began appearing in the US medical literature in the 1980s. By mid-1993, of the 72 case reports of women with breast implants and connective tissue disease, 38 were reported to have scleroderma. As a result of the publication of these case reports, a number of epidemiologic studies were conducted to find out if silicone breast implants are associated with the development of scleroderma. Five case-control studies of scleroderma were done, plus four prospective studies of connective tissue diseases (including scleroderma) and breast implants. In eight other epidemiologic studies, no cases of scleroderma were identified among women with breast implants. This article includes a qualitative review of the epidemiologic studies and a quantitative summary (meta-analysis) of the case-control studies. Neither the case-control studies nor the other epidemiologic data support the hypothesis that scleroderma is associated with or causally related to breast implants. PMID:9308408

Whorton, D; Wong, O

1997-01-01

309

Ion implanted dielectric elastomer circuits  

NASA Astrophysics Data System (ADS)

Starfish and octopuses control their infinite degree-of-freedom arms with panache—capabilities typical of nature where the distribution of reflex-like intelligence throughout soft muscular networks greatly outperforms anything hard, heavy, and man-made. Dielectric elastomer actuators show great promise for soft artificial muscle networks. One way to make them smart is with piezo-resistive Dielectric Elastomer Switches (DES) that can be combined with artificial muscles to create arbitrary digital logic circuits. Unfortunately there are currently no reliable materials or fabrication process. Thus devices typically fail within a few thousand cycles. As a first step in the search for better materials we present a preliminary exploration of piezo-resistors made with filtered cathodic vacuum arc metal ion implantation. DES were formed on polydimethylsiloxane silicone membranes out of ion implanted gold nano-clusters. We propose that there are four distinct regimes (high dose, above percolation, on percolation, low dose) in which gold ion implanted piezo-resistors can operate and present experimental results on implanted piezo-resistors switching high voltages as well as a simple artificial muscle inverter. While gold ion implanted DES are limited by high hysteresis and low sensitivity, they already show promise for a range of applications including hysteretic oscillators and soft generators. With improvements to implanter process control the promise of artificial muscle circuitry for soft smart actuator networks could become a reality.

O'Brien, Benjamin M.; Rosset, Samuel; Anderson, Iain A.; Shea, Herbert R.

2013-06-01

310

Retinal implants: a systematic review.  

PubMed

Retinal implants present an innovative way of restoring sight in degenerative retinal diseases. Previous reviews of research progress were written by groups developing their own devices. This systematic review objectively compares selected models by examining publications describing five representative retinal prostheses: Argus II, Boston Retinal Implant Project, Epi-Ret 3, Intelligent Medical Implants (IMI) and Alpha-IMS (Retina Implant AG). Publications were analysed using three criteria for interim success: clinical availability, vision restoration potential and long-term biocompatibility. Clinical availability: Argus II is the only device with FDA approval. Argus II and Alpha-IMS have both received the European CE Marking. All others are in clinical trials, except the Boston Retinal Implant, which is in animal studies. Vision restoration: resolution theoretically correlates with electrode number. Among devices with external cameras, the Boston Retinal Implant leads with 100 electrodes, followed by Argus II with 60 electrodes and visual acuity of 20/1262. Instead of an external camera, Alpha-IMS uses a photodiode system dependent on natural eye movements and can deliver visual acuity up to 20/546. Long-term compatibility: IMI offers iterative learning; Epi-Ret 3 is a fully intraocular device; Alpha-IMS uses intraocular photosensitive elements. Merging the results of these three criteria, Alpha-IMS is the most likely to achieve long-term success decades later, beyond current clinical availability. PMID:24403565

Chuang, Alice T; Margo, Curtis E; Greenberg, Paul B

2014-07-01

311

Implantable Cardioverter Defibrillators. Prophylactic Use  

PubMed Central

Executive Summary Objective The use of implantable cardiac defibrillators (ICDs) to prevent sudden cardiac death (SCD) in patients resuscitated from cardiac arrest or documented dangerous ventricular arrhythmias (secondary prevention of SCD) is an insured service. In 2003 (before the establishment of the Ontario Health Technology Advisory Committee), the Medical Advisory Secretariat conducted a health technology policy assessment on the prophylactic use (primary prevention of SCD) of ICDs for patients at high risk of SCD. The Medical Advisory Secretariat concluded that ICDs are effective for the primary prevention of SCD. Moreover, it found that a more clearly defined target population at risk for SCD that would be likely to benefit from ICDs is needed, given that the number needed to treat (NNT) from recent studies is 13 to 18, and given that the per-unit cost of ICDs is $32,000, which means that the projected cost to Ontario is $770 million (Cdn). Accordingly, as part of an annual review and publication of more recent articles, the Medical Advisory Secretariat updated its health technology policy assessment of ICDs. Clinical Need Sudden cardiac death is caused by the sudden onset of fatal arrhythmias, or abnormal heart rhythms: ventricular tachycardia (VT), a rhythm abnormality in which the ventricles cause the heart to beat too fast, and ventricular fibrillation (VF), an abnormal, rapid and erratic heart rhythm. About 80% of fatal arrhythmias are associated with ischemic heart disease, which is caused by insufficient blood flow to the heart. Management of VT and VF with antiarrhythmic drugs is not very effective; for this reason, nonpharmacological treatments have been explored. One such treatment is the ICD. The Technology An ICD is a battery-powered device that, once implanted, monitors heart rhythm and can deliver an electric shock to restore normal rhythm when potentially fatal arrhythmias are detected. The use of ICDs to prevent SCD in patients resuscitated from cardiac arrest or documented dangerous ventricular arrhythmias (secondary prevention) is an insured service in Ontario. Primary prevention of SCD involves identification of and preventive therapy for patients who are at high risk for SCD. Most of the studies in the literature that have examined the prevention of fatal ventricular arrhythmias have focused on patients with ischemic heart disease, in particular, those with heart failure (HF), which has been shown to increase the risk of SCD. The risk of HF is determined by left ventricular ejection fraction (LVEF); most studies have focused on patients with an LVEF under 0.35 or 0.30. While most studies have found ICDs to reduce significantly the risk for SCD in patients with an LVEF less than 0.35, a more recent study (Sudden Cardiac Death in Heart Failure Trial [SCD-HeFT]) reported that patients with HF with nonischemic heart disease could also benefit from this technology. Based on the generalization of the SCD-HeFT study, the Centers for Medicare and Medicaid in the United States recently announced that it would allocate $10 billion (US) annually toward the primary prevention of SCD for patients with ischemic and nonischemic heart disease and an LVEF under 0.35. Review Strategy The aim of this literature review was to assess the effectiveness, safety, and cost effectiveness of ICDs for the primary prevention of SCD. The standard search strategy used by the Medical Advisory Secretariat was used. This included a search of all international health technology assessments as well as a search of the medical literature from January 2003–May 2005. A modification of the GRADE approach (1) was used to make judgments about the quality of evidence and strength of recommendations systematically and explicitly. GRADE provides a framework for structured reflection and can help to ensure that appropriate judgments are made. GRADE takes into account a study’s design, quality, consistency, and directness in judging the quality of evidence for each outcome. The balance between benefits and harms, quality of e

2005-01-01

312

21 CFR 872.3970 - Interarticular disc prosthesis (interpositional implant).  

Code of Federal Regulations, 2010 CFR

...2010-04-01 false Interarticular disc prosthesis (interpositional implant). 872... § 872.3970 Interarticular disc prosthesis (interpositional implant). (a) Identification. An interarticular disc prosthesis (interpositional implant) is...

2010-04-01

313

FISH for Pre-implantation Genetic Diagnosis  

PubMed Central

Pre-implantation genetic diagnosis (PGD) is an established alternative to pre-natal diagnosis, and involves selecting pre-implantation embryos from a cohort generated by assisted reproduction technology (ART). This selection may be required because of familial monogenic disease (e.g. cystic fibrosis), or because one partner carries a chromosome rearrangement (e.g. a two-way reciprocal translocation). PGD is available for couples who have had previous affected children, and/or in the case of chromosome rearrangements, recurrent miscarriages, or infertility. Oocytes aspirated following ovarian stimulation are fertilized by in vitro immersion in semen (IVF) or by intracytoplasmic injection of an individual spermatozoon (ICSI). Pre-implantation cleavage-stage embryos are biopsied, usually by the removal of a single cell on day 3 post-fertilization, and the biopsied cell is tested to establish the genetic status of the embryo. Fluorescence in situ hybridization (FISH) on the fixed nuclei of biopsied cells with target-specific DNA probes is the technique of choice to detect chromosome imbalance associated with chromosome rearrangements, and to select female embryos in families with X-linked disease for which there is no mutation-specific test. FISH has also been used to screen embryos for spontaneous chromosome aneuploidy (also known as PGS or PGD-AS) in order to try and improve the efficiency of assisted reproduction; however, the predictive value of this test using the spreading and FISH technique described here is likely to be unacceptably low in most people's hands and it is not recommended for routine clinical use. We describe the selection of suitable probes for single-cell FISH, spreading techniques for blastomere nuclei, and in situ hybridization and signal scoring, applied to PGD in a clinical setting. PMID:21403624

Scriven, Paul N.; Kirby, Toby L.; Ogilvie, Caroline Mackie

2011-01-01

314

Peri-implant mucositis and peri-implantitis: clinical and histopathological characteristics and treatment.  

PubMed

Osseointegrated dental implants are used routinely in dentistry in the confidence of predictable success. However, if the implant surfaces become colonised by pathogenic bacteria, the plaque-induced inflammation around the implants may cause peri-implant tissue destruction. Peri-implant mucositis is a reversible, plaque-induced inflammatory lesion confined to the peri-implant soft tissue unit and clinically is characterised by redness, swelling and bleeding on gentle probing. Peri-implantitis is an extension of peri-implant mucositis to involve the bone supporting the implant: it is characterised by loss of osseointegration of the coronal part of the implant, by increased probing depth and by bleeding and/or suppuration on probing. Established peri-implantitis does not respond predictably to treatment. The best management of plaque-induced peri-implant inflammatory diseases is prevention. Regular personal and professional cleaning of the implant is mandatory to minimise bacterial load. Despite our best efforts, plaque-induced peri-implant inflammatory diseases will occur frequently, and as these diseases respond best to early treatment, early detection of peri-implant mucositis by regular assessment will permit timely treatment. Peri-implant mucositis is readily treated non-surgically. Peri-implantitis is more difficult to treat largely because of the problem of decontamination of the roughened, threaded surfaces of exposed implants. As a rule, surgical treatment will be necessary, and even then success is not assured. PMID:23198360

Khammissa, R A G; Feller, L; Meyerov, R; Lemmer, J

2012-04-01

315

Cyborg Technology  

NSDL National Science Digital Library

Discussions of cyborg technology tend to be relegated to science fiction literature and TV programs like Star Trek. This Topic in Depth looks into current issues and developments in the area of cyborg technology. The first website, from the UC Santa Barbara Department of English, (1) lists a variety of resources on cyborgs, from philosophical articles and literary criticism to current scientific practices. A related area of research is brain-computer interfacing (BCI), which is described on this website from the Helsinki Institute of Technology (2). Research on neural engineering, which combines work in electrical and computer engineering, tissue engineering, materials science, and nanotechnology, is also described on this website from USC (3). The Discovery School (4) suggests this lesson on technology for grades six through eight, in which students explore how the human body uses electric signals to send messages to and from the brain, and then how the nervous system uses those signals, with the option for additional discussions regarding the potential for cyborg technology. The next website from National Public Radio (5) provides a current look at applications of cyber technology, most of which are in the area of healthcare. For example, this program reports on how "scientists make it possible for quadriplegics to control a television, play simple computer games and check e-mail... by just thinking about it." Another interesting experiment--Project Cyborg--involves the neuro-surgical implantation of a device into the median nerves of this researchers' left arm and is described this website (6).

316

The impact of network and recency effects on the adoption of e-collaboration technologies in online communities  

Microsoft Academic Search

This study investigates the impact that network and recency effects have on the adoption of e-collaboration technologies (ECT).\\u000a The network effect is a widely documented phenomenon affecting the adoption of technology in the real world. However, its\\u000a impact in virtual workspaces remains relatively underexplored. We know little about whether the observed network effect in\\u000a offline settings also applies to online

Gang Peng; Peter Woodlock

2009-01-01

317

What is "effective treatment" for a schizophrenic inpatient with persistent treatment-resistant psychosis and severe violent behavior?: a case of ECT.  

PubMed

Aggressive behavior among treatment-resistant schizophrenic patients is a major clinical challenge whose prevalence is underestimated.In our 420-bed psychiatric hospital, some 15% of patients exhibit active psychosis and high rates of verbal/physical aggression necessitating physical restraints. In addition to their condition, these individuals endanger staff and other patients, consume extensive resources, and induce a sense of clinical helplessness.Physicians managing such complex patients face dilemmas regarding choice of treatment, criteria for treatment decisions, treatment goals, and outcome assessments. We address some of these by following the progress of a persistently psychotic severely aggressive treatment-resistant inpatient treated with repeated electroconvulsive therapy (ECT). The motivation for this report was our desire to examine whether there was objective evidence to support our clinically based treatment decisions.To this end, we compiled a retrospective chronological life chart recording ECT administrations and aggression using case note information. Physical restraint was chosen as the outcome measure, as it was accurately documented. Because it was used only after all other means failed, a recorded incident represents an extreme peak of ongoing aggressive behavior. PMID:24263278

Isakov, Victoria; Tsvelikhovsky, Irena; Goldin, Vladimir; Silver, Henry

2013-12-01

318

Characterizations of additive manufactured porous titanium implants.  

PubMed

This article describes physical, chemical, and mechanical characterizations of porous titanium implants made by an additive manufacturing method to gain insight into the correlation of process parameters and final physical properties of implants used in orthopedics. For the manufacturing chain, the powder metallurgy technology was combined with the additive manufacturing to fabricate the porous structure from the pure tanium powder. A 3D printing machine was employed in this study to produce porous bar samples. A number of physical parameters such as titanium powder size, polyvinyl alcohol (PVA) amount, sintering temperature and time were investigated to control the mechanical properties and porosity of the structures. The produced samples were characterized through porosity and shrinkage measurements, mechanical compression test and scanning electron microscopy (SEM). The results showed a level of porosity in the samples in the range of 31-43%, which is within the range of the porosity of the cancelluous bone and approaches the range of the porosity of the cortical bone. The results of the mechanical test showed that the compressive strength is in the wide range of 56-509 MPa implying the effect of the process parameters on the mechanical strengths. This technique of manufacturing of Ti porous structures demonstrated a low level of shrinkage with the shrinkage percentage ranging from 1.5 to 5%. PMID:22865677

Basalah, Ahmad; Shanjani, Yaser; Esmaeili, Shahrzad; Toyserkani, Ehsan

2012-10-01

319

Design features of implants for direct skeletal attachment of limb prostheses  

PubMed Central

In direct skeletal attachment (DSA) of limb prostheses, a construct is implanted into an amputee’s residuum bone and protrudes out of the residuum’s skin. This technology represents an alternative to traditional suspension of prostheses via various socket systems, with clear indications when the sockets cannot be properly fitted. Contemporary DSA was invented in the 1990s, and several implant systems have been introduced since then. The current review is intended to compare the design features of implants for DSA whose use in humans or in animal studies has been reported in the literature. PMID:23554122

Pitkin, M.

2013-01-01

320

Preformed acrylic cranial implants using fused deposition modeling: a clinical report.  

PubMed

Fabrication of acrylic cranial implants by conventional methods of moulage and mold formation may be difficult when the margin of the defect cannot be accurately detected. Three-dimensional anatomic models built by fused deposition modeling can serve as templates for the fabrication of custom acrylic implants for large or complicated cranial defects. Virtual mirror imaging of the contralateral nondefect side can facilitate the restoration of symmetry in appearance-sensitive areas. This clinical report presents a method for the fabrication of cranial implants for 2 patients using anatomic modeling technology. PMID:14586305

Gronet, Peter M; Waskewicz, Gregory A; Richardson, Charles

2003-11-01

321

Transcatheter aortic valve implantation: what has been done and what is going to be done.  

PubMed

Transcatheter valve implantation is developing into an effective and reproducible therapy for aortic valve stenosis. The origin of this technique was pursued in 1992 when Andersen demonstrated the feasibility of percutaneous implantation of catheter-based valve prosthesis. Since then a lot of technical and device advances have been made and to date, transcatheter aortic valve implantation has became a concrete alternative to surgical replacement. This paper aims to go over all the current devices, from the most widely used to the newest technology, focusing on device description, procedural issues, potential complications and clinical studies currently available in literature. PMID:20014989

Tamburino, Corrado; Barbanti, Marco; Capodanno, Davide; Ussia, Gian Paolo

2010-01-01

322

Shape memory effect and superelasticity of titanium nickelide alloys implanted with high ion doses  

NASA Astrophysics Data System (ADS)

The state of the art in ion implantation of superelastic NiTi shape memory alloys is analyzed. Various technological applications of the shape memory effect are outlined. The principles and techiques of ion implantation are described. Specific features of its application for modification of surface layers in surface engineering are considered. Key properties of shape memory alloys and problems in utilization of ion implantation to improve the surface properties of shape memory alloys, such as corrosion resistance, friction coefficient, wear resistance, etc. are discussed. The bibliography includes 162 references.

Pogrebnjak, A. D.; Bratushka, S. N.; Beresnev, V. M.; Levintant-Zayonts, N.

2013-12-01

323

&dkd March 11, 1926 hopEd t o find somE wEathE:r cycle connEctEd with thE CYCLE of thE moon -PErbPS  

E-print Network

&dkd March 11, 1926 hopEd t o find somE wEathE:r cycle connEctEd with thE CYCLE of thE moon - PErbEr thE ExpEctEd guiding E f f E c t of t h E full moon. But thE moon ExErta practically no dirizct control Ov millionth t h E intensity Of dirwt sunlight, mlEthEr o r not t h E moon has any cclntrol ovtrr Iont; prriod

324

State-of-the-art on cone beam CT imaging for preoperative planning of implant placement  

Microsoft Academic Search

Orofacial diagnostic imaging has grown dramatically in recent years. As the use of endosseous implants has revolutionized\\u000a oral rehabilitation, a specialized technique has become available for the preoperative planning of oral implant placement:\\u000a cone beam computed tomography (CT). This imaging technology provides 3D and cross-sectional views of the jaws. It is obvious\\u000a that this hardware is not in the same

Maria Eugenia Guerrero; Reinhilde Jacobs; Miet Loubele; Filip Schutyser; Paul Suetens; Daniel van Steenberghe

2006-01-01

325

A 100kV\\/200A Blumlein Pulser for High-Energy Plasma Implantation  

Microsoft Academic Search

A high voltage pulsed power supply of 100 kV\\/200 A with output short pulses on the order 1 mus (based on stacked coaxial Blumlein technology) was developed for use in surface treatment of materials by plasma implantation. The plasma implantation process requires pulse repetition and our device is capable of operating at a frequency range of 10-150 Hz, depending on

J. O. Rossif; M. Ueda

2005-01-01

326

A Paradigm for the Development and Evaluation of Novel Implant Topologies for Bone Fixation: In Vivo Evaluation  

PubMed Central

While contemporary prosthetic devices restore some function to individuals who have lost a limb, there are efforts to develop bio-integrated prostheses to improve functionality. A critical step in advancing this technology will be to securely attach the device to remnant bone. To investigate mechanisms for establishing robust implant fixation in bone while undergoing loading, we previously used a topology optimization scheme to develop optimized orthopaedic implants and then fabricated selected designs from titanium (Ti)-alloy with selective laser sintering (SLS) technology. In the present study, we examined how implant architecture and mechanical stimulation influence osseointegration within an in vivo environment. To do this, we evaluated three implant designs (two optimized and one non-optimized) using a unique in vivo model that applied cyclic, tension/ compression loads to the implants. Eighteen (six per implant design) adult male canines had implants surgically placed in their proximal, tibial metaphyses. Experimental duration was 12 weeks; daily loading (peak load of ±22N for 1000 cycles) was applied to one of each animal’s bilateral implants for the latter six weeks. Following harvest, osseointegration was assessed by non-destructive mechanical testing, micro-computed tomography (microCT) and back-scatter scanning electron microscopy (SEM). Data revealed that implant loading enhanced osseointegration by significantly increasing construct stiffness, peri-implant trabecular morphology, and percentages of interface connectivity and bone ingrowth. While this experiment did not demonstrate a clear advantage associated with the optimized implant designs, osseointegration was found to be significantly influenced by aspects of implant architecture. PMID:22951278

Long, Jason P.; Hollister, Scott J.; Goldstein, Steven A.

2012-01-01

327

Volumetric Flow Measurement Using an Implantable CMUT Array  

Microsoft Academic Search

This paper describes volumetric-flow velocity measurement using an implantable capacitive micromachined ultrasonic transducer (CMUT) array. The array is comprised of multiple-concentric CMUT rings for ultrasound transmission and an outmost annular CMUT array for ultrasound reception. Microelectromechanical-system (MEMS) fabrication technology allows reception CMUT on this flowmeter to be implemented with a different membrane thickness and gap height than that of transmission

Mengli Wang; Jingkuang Chen

2011-01-01

328

Complications at the Time of Transcatheter Aortic Valve Implantation  

PubMed Central

Transcatheter aortic valve implantation (TAVI) improves the prognosis of patients with severe aortic stenosis who are deemed too high risk for surgical valve replacement.1 However, this evolving technology is associated with a wide range of potential complications — some specific to TAVI, some often fatal. Prevention, early recognition, and effective treatment of these complications will significantly improve the outcome of this procedure and are essential prerequisites before the therapy is extended to lower-risk patient subsets. PMID:22891127

Brecker, Stephen J.D.; Roy, David; Jahangiri, Marjan

2012-01-01

329

Multimodality Noninvasive Imaging for Transcatheter Aortic Valve Implantation: A primer  

PubMed Central

Transcatheter aortic valve implantation (TAVI) has recently emerged as a treatment option for patients with severe aortic valve stenosis (AS). For patients who are deemed inoperable for surgical aortic valve replacement (SAVR), TAVI has a significant mortality benefit compared to medical therapy. This review discusses established and emerging roles for multimodality imaging and focuses on the application of these technologies for patient selection, intraprocedural guidance, and the detection and quantification of acute and chronic complications of this novel procedure. PMID:22891126

Shah, Dipan J.; Mahmarian, John J.

2012-01-01

330

MRI artefacts after Bonebridge implantation.  

PubMed

The new transcutaneous bone conduction implant (BCI) Bonebridge (BB, MED-EL) allows the skin to remain intact and therefore overcomes some issues related to percutaneous systems, such as skin reaction around the external screw and cosmetic complaints. According to manufacturer, BB is MRI conditional up to 1,5 Tesla (T). The artefact of the neurocranium after BB implantation is extensive as shown in the present report. This has to be taken into account when patients suffering conductive, mixed or single-sided hearing loss with candidacy for a BCI are counselled. In patients with comorbid intracranial tumour or other diseases of the brain that require imaging control scans with MRI percutaneous, BCI should be the implant of choice considering the very small artefact of the percutaneous screw in MRI. PMID:24639341

Steinmetz, C; Mader, I; Arndt, S; Aschendorff, A; Laszig, R; Hassepass, F

2014-07-01

331

Selective oxidation technologies for high density MOS  

Microsoft Academic Search

Selective oxidation technologies using various thicknesses of silicon nitride formed by low-pressure chemical vapor deposition (LPCVD), plasma assisted nitridation in ammonia, and by nitrogen ion implantation were investigated. The transition region (\\

J. Hui; T. Y. Chiu; S. Wong; W. G. Oldham

1981-01-01

332

21 CFR 522.1350 - Melatonin implant.  

Code of Federal Regulations, 2010 CFR

...One implant per mink. (2) Indications for use . For use in healthy male and female kit and adult female mink (Mustela vison ) to accelerate the fur priming cycle. (3) Limitations . For subcutaneous implantation in mink only....

2010-04-01

333

21 CFR 522.1350 - Melatonin implant.  

Code of Federal Regulations, 2013 CFR

...One implant per mink. (2) Indications for use . For use in healthy male and female kit and adult female mink (Mustela vison ) to accelerate the fur priming cycle. (3) Limitations . For subcutaneous implantation in mink only....

2013-04-01

334

21 CFR 522.1350 - Melatonin implant.  

Code of Federal Regulations, 2012 CFR

...One implant per mink. (2) Indications for use . For use in healthy male and female kit and adult female mink (Mustela vison ) to accelerate the fur priming cycle. (3) Limitations . For subcutaneous implantation in mink only....

2012-04-01

335

21 CFR 522.1350 - Melatonin implant.  

Code of Federal Regulations, 2011 CFR

...One implant per mink. (2) Indications for use . For use in healthy male and female kit and adult female mink (Mustela vison ) to accelerate the fur priming cycle. (3) Limitations . For subcutaneous implantation in mink only....

2011-04-01

336

21 CFR 522.1350 - Melatonin implant.  

...One implant per mink. (2) Indications for use. For use in healthy male and female kit and adult female mink (Mustela vison ) to accelerate the fur priming cycle. (3) Limitations. For subcutaneous implantation in mink only....

2014-04-01

337

A low-power cochlear implant system  

E-print Network

Cochlear implants, or bionic ears, restore hearing to the profoundly deaf by bypassing missing inner-ear hair cells in the cochlea and electrically stimulating the auditory nerve. For miniaturized cochlear implants, including ...

Baker, Michael W. (Michael Warren), 1977-

2007-01-01

338

21 CFR 878.4750 - Implantable staple.  

Code of Federal Regulations, 2012 CFR

...FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4750 Implantable staple. (a) Identification. An implantable...

2012-04-01

339

21 CFR 878.4750 - Implantable staple.  

...FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4750 Implantable staple. (a) Identification. An implantable...

2014-04-01

340

21 CFR 878.4300 - Implantable clip.  

...FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4300 Implantable clip. (a) Identification. An implantable clip...

2014-04-01

341

21 CFR 878.4750 - Implantable staple.  

Code of Federal Regulations, 2011 CFR

...FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4750 Implantable staple. (a) Identification. An implantable...

2011-04-01

342

21 CFR 878.4300 - Implantable clip.  

Code of Federal Regulations, 2011 CFR

...FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4300 Implantable clip. (a) Identification. An implantable clip...

2011-04-01

343

21 CFR 878.4750 - Implantable staple.  

Code of Federal Regulations, 2013 CFR

...FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4750 Implantable staple. (a) Identification. An implantable...

2013-04-01

344

21 CFR 878.4300 - Implantable clip.  

Code of Federal Regulations, 2013 CFR

...FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4300 Implantable clip. (a) Identification. An implantable clip...

2013-04-01

345

FDA Breast Implant Consumer Handbook, 2004.  

National Technical Information Service (NTIS)

Contents: Glossary; Introduction; Device Description; Status/Availability; Local Complications & Reoperations; Diseases; Specific Issues to Consider; Breast Implant Surgery & Related Issues; Resource Groups; Timeline of Breast Implant Activities; Medwatch...

2004-01-01

346

21 CFR 878.4300 - Implantable clip.  

Code of Federal Regulations, 2012 CFR

...FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4300 Implantable clip. (a) Identification. An implantable clip...

2012-04-01

347

Assessment of Implantation in the Rat.  

National Technical Information Service (NTIS)

A series of protocols has been assembled and used for the assessment of implantation failure following chemical exposure in the rat. Upon detecting a chemically-induced blockade of implantation, these protocols are designed to probe the physiological mech...

A. M. Cummings

1991-01-01

348

Novel CBCT and optical scanner-based implant treatment planning using a stereolithographic surgical guide: a multipronged diagnostic approach.  

PubMed

This report describes the use of the combination of 2 technologies (Cone-beam computed tomography and Optical 3-dimensional scan) to maximize accuracy of implant placement in an area where previous implants failed and had to be removed. This report also stresses the increased efficiency of combining technologies to fabricate stereolithographic surgical guide which, when used intraoperatively, can improve precision of placement. PMID:25051414

Balasundaram, Ashok; Gurun, Dincer; Neely, Anthony; Ash-Rafzadeh, Armand; Ravichandra, Juluri

2014-08-01

349

Implant-supported facial prostheses.  

PubMed

The application of the principles of osseointegration to the craniofacial skeleton can offer the patient with defects from trauma or ablative cancer surgery a functional and esthetic restoration, with minimal morbidity. Implant-supported restorations offer a retrievable prosthesis with increased retention and support, by the use of tissue bars with clip retention, magnetic retentive mechanisms, or both. Implant-supported auricular, nasal, orbital, midfacial or combination prostheses are presently being provided for patients in hospitals, maxillofacial prosthetic training programs, and private practice settings in North America and elsewhere. PMID:9520655

Baima, R F

1996-01-01

350

Digital planning of cranial implants.  

PubMed

Computer-aided techniques can be used in the reconstruction of defects in the skull, although there are limitations for large defects. We describe a technique for the digital design of an implant for cranioplasty using one, easy-to-use, piece of generic industrial software that shows a curvature-based, hole-filling algorithm. This approach is suitable for all kinds of defects, including those that extend across the midline of the skull. The workflow gives the user full control over the design, production, and material used for the implant. PMID:23266152

van der Meer, Wicher J; Bos, Ruud R M; Vissink, Arjan; Visser, Anita

2013-07-01

351

Immediate and early replacement implants and restorations.  

PubMed

There have been rapid developments in dental implant treatment protocols to reduce the time between implant placement and restoration. Implants may be placed immediately following tooth extraction or following a period of healing to allow resolution of residual infection or sufficient bone and soft tissue healing. Early restoration and loading of implants has to be carefully controlled to avoid increased failure and complications. Advantages and disadvantages of the various techniques are described. PMID:18561804

Palmer, R M; Palmer, P J; Baker, P

2008-03-01

352

Full rehabilitation with nobel clinician® and procera implant bridge®: case report  

PubMed Central

SUMMARY Implant surgery has been changing in different ways following improvements of computer technologies. Since its beginning, according to the original procedures of Branemårk system implants, guide-lines in implants-supported prosthetic rehabilitation have been founding on the placement of fixtures in a fairly upright position, after maxillary sinus floor elevation; while in the case of interforaminal rehabilitation, an upright distal implant may need to be placed anterior to the mental foramina without nerve damage (although the consequence would have been bilateral cantilevers to provide good chewing capacity). Some authors have proposed engaging the molar/tuberosity area: Bahat and Venturelli demonstrated these areas reliable and predictable alternative to distal cantilever prostheses or sinus elevation procedures. In recent years, the immediate loading of tilted implants with a provisional restoration has been proposed for the treatment of the atrophic maxilla. Tilted posterior implants in either arches could avoid (cantilever length) and provide to a better load distribution. Further studies have showed excellent outcomes for both tilted and axial implants; indeed this protocol allows to use longer implants, improve bone anchorage and avoid bone grafting procedures. Malò at al., in a retrospective clinical study, showed important results using two posterior tilted implants and two anterior non-tilted ones in the so-called All-on-four technique (Nobel Biocare, Göteborg, Sweden). Instead of the great loss of bone (amount and quality) in long-term edentuly the clinically documented computer-guided implantology software is able, through posterior tilted implants, to improve load distribution. Many authors have reported reduced surgical invasion (sinus grafting surgery is needless), shorter treatment time, lower cost, natural aesthetic profiles and functional bite. PMID:24175051

SPINELLI, D.; OTTRIA, L.; DE VICO, G.; BOLLERO, R.; BARLATTANI, A.; BOLLERO, P.

2013-01-01

353

Design optimization of functionally graded dental implant.  

PubMed

The continuous increase of man's life span, and the growing confidence in using artificial materials inside the human body necessities introducing more effective prosthesis and implant materials. However, no artificial implant has biomechanical properties equivalent to the original tissue. Recently, titanium and bioceramic materials, such as hydroxyapatite are extensively used as fabrication materials for dental implant due to their high compatibility with hard tissue and living bone. Titanium has reasonable stiffness and strength while hydroxyapatite has low stiffness, low strength and high ability to reach full integration with living bone. In order to obtain good dental implantation of the biomaterial; full integration of the implant with living bone should be satisfied. Minimum stresses in the implant and the bone must be achieved to increase the life of the implant and prevent bone resorption. Therefore, the aim of the current investigation is to design an implant made from functionally graded material (FGM) to achieve the above advantages. The finite element method and optimization technique are used to reach the required implant design. The optimal materials of the FGM dental implant are found to be hydroxyapatite/titanium. The investigations have shown that the maximum stress in the bone for the hydroxyapatite/titanium FGM implant has been reduced by about 22% and 28% compared to currently used titanium and stainless steel dental implants, respectively. PMID:15156104

Hedia, H S; Mahmoud, Nemat-Alla

2004-01-01

354

Music recognition by children with cochlear implants  

Microsoft Academic Search

Poor pitch resolution interferes with cochlear implant users' ability to recognize music from pitch cues alone. We examined the possibility that prelingually deaf implant users could identify familiar hit songs from commercial recordings presented with or without words. Young implant users 8–18 years of age and age-matched hearing controls attempted to identify original and altered recordings of familiar hit songs.

Tara Vongpaisal; Sandra E. Trehub; E. Glenn Schellenberg; Blake Papsin

2004-01-01

355

The failed first metatarsophalangeal joint implant arthroplasty.  

PubMed

Chronic pain in a first metatarsophalangeal implant arthroplasty can be early or late, and may be due to infection or implant failure. Although excisional arthroplasty can be considered, the most predictable result will come from arthrodesis. Conversion of a failed implant arthroplasty to fusion will usually require structural bone graft, with slower healing times than primary fusion. PMID:25129347

Greisberg, Justin

2014-09-01

356

Instrumented hip implants: electric supply systems.  

PubMed

Instrumented hip implants were proposed as a method to monitor and predict the biomechanical and thermal environment surrounding such implants. Nowadays, they are being developed as active implants with the ability to prevent failures by loosening. The generation of electric energy to power active mechanisms of instrumented hip implants remains a question. Instrumented implants cannot be implemented without effective electric power systems. This paper surveys the power supply systems of seventeen implant architectures already implanted in-vivo, namely from instrumented hip joint replacements and instrumented fracture stabilizers. Only inductive power links and batteries were used in-vivo to power the implants. The energy harvesting systems, which were already designed to power instrumented hip implants, were also analyzed focusing their potential to overcome the disadvantages of both inductive-based and battery-based power supply systems. From comparative and critical analyses of the methods to power instrumented implants, one can conclude that: inductive powering and batteries constrain the full operation of instrumented implants; motion-driven electromagnetic energy harvesting is a promising method to power instrumented passive and active hip implants. PMID:24050511

Soares dos Santos, Marco P; Ferreira, Jorge A F; Ramos, A; Simões, José A O; Morais, Raul; Silva, Nuno M; Santos, Paulo M; Reis, M J C S; Oliveira, T

2013-10-18

357

Morphological Features of Peri-Implant Tissue after Placement of Dental Implants into the Extraction Socket  

Microsoft Academic Search

In experiments on pigs, bone regeneration was studied after implantation of implants with four cylindrical roots and support\\u000a cone and laminar crest-shaped implants with shape memory effect. The implants were placed to the extraction socket (mandibular\\u000a canine) and through the socket immediately after tooth extraction using osteoplastic material or without using collapan-L.\\u000a The use of collapan-L accelerated regeneration of peri-implant

M. V. Kotenko; L. L. Meysner

358

Cortical plasticity after cochlear implantation.  

PubMed

The most dramatic progress in the restoration of hearing takes place in the first months after cochlear implantation. To map the brain activity underlying this process, we used positron emission tomography at three time points: within 14 days, three months, and six months after switch-on. Fifteen recently implanted adult implant recipients listened to running speech or speech-like noise in four sequential PET sessions at each milestone. CI listeners with postlingual hearing loss showed differential activation of left superior temporal gyrus during speech and speech-like stimuli, unlike CI listeners with prelingual hearing loss. Furthermore, Broca's area was activated as an effect of time, but only in CI listeners with postlingual hearing loss. The study demonstrates that adaptation to the cochlear implant is highly related to the history of hearing loss. Speech processing in patients whose hearing loss occurred after the acquisition of language involves brain areas associated with speech comprehension, which is not the case for patients whose hearing loss occurred before the acquisition of language. Finally, the findings confirm the key role of Broca's area in restoration of speech perception, but only in individuals in whom Broca's area has been active prior to the loss of hearing. PMID:24377050

Petersen, B; Gjedde, A; Wallentin, M; Vuust, P

2013-01-01

359

Auditory neuropathy and cochlear implantation  

Microsoft Academic Search

This work was undertaken to study the prevalence of auditory neuropathy among deaf subjects “as diagnosed by objective tests for peripheral neuropathy” together with their performance using the cochlear implant (CI) device. Thirty-five adult CI subjects versus twenty subjects with sensorineural hearing loss of both genders and of variable etiology of hearing loss were included. Electrophysiological testing of peripheral nerves

S Soliman; N Kamal; S Ashour

2003-01-01

360

Contamination Control in Ion Implantation  

SciTech Connect

The investigation and elimination or control of metallic contamination in ion implanters has been a leading, continuous effort at implanter OEMs and in fabs/IDMs alike. Much of the efforts have been in the area of control of sputtering through material and geometry changes in apertures, beamline and target chamber components. In this paper, we will focus on an area that has not, heretofore, been fully investigated or controlled. This is the area of lubricants and internal and external support material such as selected cleaning media. Some of these materials are designated for internal use (beamline/vacuum) only while others are for internal and/or external use. Many applications for selected greases, for example, are designated for or are used for platens, implant disks/wheels and for wafer handling components. We will present data from popular lubricants (to be unnamed) used worldwide in ion implanters. This paper will review elements of concern in many lubricants that should be tracked and monitored by all fabs.Proper understanding of the characteristics, risks and the control of these potential contaminants can provide for rapid return to full process capability following major PMs or parts changes. Using VPD-ICPMS, Glow Discharge Mass Spectrometry and Ion Chromatography (IC) data, we will review the typical cleaning results and correlation to ''on wafer'' contamination by elements of concern--and by some elements that are otherwise barred from the fab.

Eddy, R. [KLE Engineering, 365 High Chaparral Loop, Prescott AZ 86303 (United States); Doi, D. [Fastgate Corporation, 1011 Niizo, Toda, Saitama 335-001 (Japan); Santos, I.; Wriggins, W. [Core Systems, 1050 Kifer Rd. Sunnyvale, CA 94086 (United States)

2011-01-07

361

Cortical Plasticity after Cochlear Implantation  

PubMed Central

The most dramatic progress in the restoration of hearing takes place in the first months after cochlear implantation. To map the brain activity underlying this process, we used positron emission tomography at three time points: within 14 days, three months, and six months after switch-on. Fifteen recently implanted adult implant recipients listened to running speech or speech-like noise in four sequential PET sessions at each milestone. CI listeners with postlingual hearing loss showed differential activation of left superior temporal gyrus during speech and speech-like stimuli, unlike CI listeners with prelingual hearing loss. Furthermore, Broca's area was activated as an effect of time, but only in CI listeners with postlingual hearing loss. The study demonstrates that adaptation to the cochlear implant is highly related to the history of hearing loss. Speech processing in patients whose hearing loss occurred after the acquisition of language involves brain areas associated with speech comprehension, which is not the case for patients whose hearing loss occurred before the acquisition of language. Finally, the findings confirm the key role of Broca's area in restoration of speech perception, but only in individuals in whom Broca's area has been active prior to the loss of hearing. PMID:24377050

Petersen, B.; Gjedde, A.; Wallentin, M.; Vuust, P.

2013-01-01

362

Clinical Experiences with Dental Implants  

Microsoft Academic Search

The clinical utilization of dental impants has accelerated in recent years, and new applications continue to emerge. Concomitantly, alternative implant systems have introduced conceptually different approaches to treatment using altered protocols. The purpose of this paper is to address some of the background issues pertinent to the long-term success, survival, safety, and effectiveness of these devices. The requirements for clinical

Patrick J. Henry

1999-01-01

363

He reemission implanted in metals  

NASA Astrophysics Data System (ADS)

Helium (He) reemission of Al, Ni and Mo under energetic He implantation (10-30 keV) in wide temperature range is studied to understand behavior of implanted He in correlation with structure changes. The reemission behavior is categorized into 4 different temperature ranges with the normalized temperature (Tm) to the melting point of each metal. At elevated temperatures (well above ?0.6 Tm), interstitial He atoms and/or He-vacancy (ies) clusters can migrate remaining no structure change and showing smooth reemission without any burst. Between ?0.25 and 0.6 Tm, He reemission always accompanies significant structure modification. For ?04-0.6 Tm, implanted He coalesce to make bubbles and the bubbles can move to the surface. Bubble migration accompanies materials flow to the surface resulting in fuzz surface or columnar structure, depending on implantation flux. Slower bubble motion at ?0.25-0.4 prohibits the material migration. Instead the bubbles coalesce to grow large and multi-layered blistering appears as periodic reemission behavior. Below ?0.25 Tm, He migration is too slow for bubbles to grow large, but bubble density increases up to a certain fluence, where neighboring bubbles start to coalesce. Accordingly, He release is mostly caused by mechanical failure or blister rapture. With increasing fluence, all defects (bubbles and dislocation loops) tangle or inter connected with neighboring defects and accordingly He migration to the surface along the tangled or connected defects is enhanced, resulting 100% reemission easily without making multilayered blistering.

Tanabe, T.

2014-10-01

364

Clinical complications of osseointegrated implants  

Microsoft Academic Search

Statement of problem. There is no comprehensive review of the literature that identifies the complications reported in clinical dental implant studies. Purpose. This article attempted to determine the types of complications that have been reported and to provide data regarding their frequency. Methods. All available clinical studies from 1981 to 1997, published in English or with English abstract, that presented

Charles J. Goodacre; Joseph Y. K. Kan; Kitichai Rungcharassaeng

1999-01-01

365

Persistent pain a ects more than half of seniors in the community and over 80 per cent of seniors in long-term care facilities. The situation is even more serious in people with severe  

E-print Network

THE ISSUE Persistent pain a ects more than half of seniors in the community and over 80 per cent in whom severe pain often goes undetected, leading to unnecessary su ering and possibly death. "Seniors,"saysThomas Hadjistavropoulos of University of Regina's Centre on Aging and Health and department of psychology. MMAMAMMMMMAKING

Saskatchewan, University of

366

Biofunctionalization of surfaces by energetic ion implantation: Review of progress on applications in implantable biomedical devices and antibody microarrays  

NASA Astrophysics Data System (ADS)

Despite major research efforts in the field of biomaterials, rejection, severe immune responses, scar tissue and poor integration continue to seriously limit the performance of today's implantable biomedical devices. Implantable biomaterials that interact with their host via an interfacial layer of active biomolecules to direct a desired cellular response to the implant would represent a major and much sought after improvement. Another, perhaps equally revolutionary, development that is on the biomedical horizon is the introduction of cost-effective microarrays for fast, highly multiplexed screening for biomarkers on cell membranes and in a variety of analyte solutions. Both of these advances will rely on effective methods of functionalizing surfaces with bioactive molecules. After a brief introduction to other methods currently available, this review will describe recently developed approaches that use energetic ions extracted from plasma to facilitate simple, one-step covalent surface immobilization of bioactive molecules. A kinetic theory model of the immobilization process by reactions with long-lived, mobile, surface-embedded radicals will be presented. The roles of surface chemistry and microstructure of the ion treated layer will be discussed. Early progress on applications of this technology to create diagnostic microarrays and to engineer bioactive surfaces for implantable biomedical devices will be reviewed.

Bilek, Marcela M. M.

2014-08-01

367

Simplifying fixed implant dental prosthetics.  

PubMed

Through following the FPPD protocol for multiple adjacent implants, and delivering final abutments, picking up the metal framework, and delivering provisionals, many benefits are gained. The benefits of following the FPPD protocol are as follows: The restorative dentist is trying-in and delivering the final abutments in one visit as opposed to removing them and placing them multiple times. This requires less chair time and time for the patient. It also reduces the mechanical stress on the abutment screw and implant body due to the elimination of multiple try-in appointments. When the metal framework is tried-in and verified for fit, the restorative dentist has the opportunity check the retention, check the margins, and make any corrections that might be needed. The abutments will be staying in the mouth when the framework is picked up. This metal try-in allows for a verification of the bite to be given to the dental lab. The delivery of provisionals manufactured by the dental laboratory offers many advantages in the FPPD technique. The patient has a form of tooth much earlier in the traditional appointment sequence. The patient can now offer feedback to the doctor and laboratory for fabrication of the permanent prosthesis with regards to shape and color. The laboratory-fabricated provisionals offer progressive loading to the implants through having a reduced occlusion yet allowing food to stimulate the implants. Overall, the FPPD technique offers shorter appointment times, more rapid delivery of fixed supported teeth, improved doctor-technician communication, and less mechanical wear on the implant parts. PMID:21306074

Tischler, Michael

2011-01-01

368

Auditory outcomes following implantation and electrical stimulation of the semicircular canals.  

PubMed

We measured auditory brainstem responses (ABRs) in eight Rhesus monkeys after implantation of electrodes in the semicircular canals of one ear, using a multi-channel vestibular prosthesis based on cochlear implant technology. In five animals, click-evoked ABR thresholds in the implanted ear were within 10 dB of thresholds in the non-implanted control ear. Threshold differences in the remaining three animals varied from 18 to 69 dB, indicating mild to severe hearing losses. Click- and tone-evoked ABRs measured in a subset of animals before and after implantation revealed a comparable pattern of threshold changes. Thresholds obtained five months or more after implantation--a period in which the prosthesis regularly delivered electrical stimulation to achieve functional activation of the vestibular system--improved in three animals with no or mild initial hearing loss and increased in a fourth with a moderate hearing loss. These results suggest that, although there is a risk of hearing loss with unilateral vestibular implantation to treat balance disorders, the surgery can be performed in a manner that preserves hearing over an extended period of functional stimulation. PMID:22504025

Bierer, Steven M; Ling, Leo; Nie, Kaibao; Fuchs, Albert F; Kaneko, Chris R S; Oxford, Trey; Nowack, Amy L; Shepherd, Sarah J; Rubinstein, Jay T; Phillips, James O

2012-05-01

369

New advanced surface modification technique: titanium oxide ceramic surface implants: long-term clinical results  

NASA Astrophysics Data System (ADS)

The purpose of this paper is to discuss the background to advanced surface modification technologies and to present a new technique, involving the formation of a titanium oxide ceramic coating, with relatively long-term results of its clinical utilization. Three general techniques are used to modify surfaces: the addition or removal of material and the change of material already present. Surface properties can also be changed without the addition or removal of material, through the laser or electron beam thermal treatment. The new technique outlined in this paper relates to the production of a corrosion-resistant 2000-2500 A thick, ceramic oxide layer with a coherent crystalline structure on the surface of titanium implants. The layer is grown electrochemically from the bulk of the metal and is modified by heat treatment. Such oxide ceramic-coated implants have a number of advantageous properties relative to implants covered with various other coatings: a higher external hardness, a greater force of adherence between the titanium and the oxide ceramic coating, a virtually perfect insulation between the organism and the metal (no possibility of metal allergy), etc. The coated implants were subjected to various physical, chemical, electronmicroscopic, etc. tests for a qualitative characterization. Finally, these implants (plates, screws for maxillofacial osteosynthesis and dental root implants) were applied in surgical practice for a period of 10 years. Tests and the experience acquired demonstrated the good properties of the titanium oxide ceramic-coated implants.

Szabo, Gyorgy; Kovacs, Lajos; Barabas, Jozsef; Nemeth, Zsolt; Maironna, Carlo

2001-11-01

370

Cerec meets Galileos--integrated implantology for completely virtual implant planning.  

PubMed

The greatest key to successful implant therapy is proper placement of the implant in the jaw bone. The key to proper placement is careful preoperative planning. When planning implant treatment, it is important to take the relevant anatomical features and their later prosthetic consequences into account. This is done using a radiographic template of the planned restoration, which until now had to be made by a dental technician. The radiographic template must be inserted in the patient's mouth during radiographic imaging so that the dentist can visualize the prosthetic plan. Implant planning is thus performed according to the backward planning principle. In the novel, fully digital approach to dental implant planning presented here, the prosthetic proposal is designed using computer-aided design software and integrated into a three-dimensional radiograph. This article explains how the technology works and reviews the available data. In addition, the clinical workflows for the SiCAT Optiguide and Sirona Cerec Guide virtual implant planning methods will be described and compared with conventional implant planning methods. Finally, the indications and countraindications for the two methods will be discussed. PMID:25098162

Reiz, Stefan D; Neugebauer, Jörg; Karapetian, Viktor-E; Ritter, Lutz

2014-01-01

371

Microgrooved silicone subcutaneous implants in guinea pigs.  

PubMed

Cell-substratum interactions are of fundamental importance for the reaction of body tissues to surgically implanted foreign materials. In our study we investigated the influence of 2 microm wide microgrooves, with various depths (0.5-6 microm), on capsule formation around subcutaneous silicone implants, in an animal experiment. Silicone sheets with microtexture were glued around silicone tubes. These implants were placed subcutaneously in eight guinea pigs for 10 weeks. The implanted tubes were removed including all surrounding tissues, and processed for light microscopy and subsequent histomorphometrical evaluation. All removed implants were surrounded by a thin fibrous capsule, and it was observed that this capsule was separated from the implants by a thin, single layer of mono- and multinucleated phagocytotic cells. In histomorphometry no significant differences were seen in relation to the reaction towards the various textures. We conclude that microtextures do not have an effect on the morphological characteristics of capsule formation around silicone implants in soft tissue. PMID:10701463

Walboomers, X F; Jansen, J A

2000-03-01

372

Early History and Challenges of Implantable Electronics  

PubMed Central

Implantable systems for biomedical research and clinical care are now a flourishing field of activities in academia as well as industrial institutions. The broad field includes experimental explorations in electronics, mechanical, chemical, and biological components and systems, and the combination of all these. Today virtually all implants involve both electronic circuits and micro-electro-mechanical-systems (MEMS). This article offers a very brief glance back at the early history of implant electronics in the period from the 1950s to the 1970s, by employing selected examples from the author’s research. This short review also discusses the challenges of implantable electronics at present, and suggests some potentially important trends in the future research and development of implantable microsystems. It is aimed as an introduction of implantable/attached electronic systems to research engineers that are interested in implantable systems as a section of Biomedical Instrumentations. PMID:24791159

KO, WEN H.

2013-01-01

373

Decontamination of dental implant surface in peri-implantitis treatment: A literature review  

PubMed Central

Etiological treatment of peri-implantitis aims to reduce the bacterial load within the peri-implant pocket and decontaminate the implant surface in order to promote osseointegration. The aim of this literature review was to evaluate the efficacy of different methods of implant surface decontamination. A search was conducted using the PubMed (Medline) database, which identified 36 articles including in vivo and in vitro studies, and reviews of different decontamination systems (chemical, mechanical, laser and photodynamic therapies). There is sufficient consensus that, for the treatment of peri-implant infections, the mechanical removal of biofilm from the implant surface should be supplemented by chemical decontamination with surgical access. However, more long-term research is needed to confirm this and to establish treatment protocols responding to different implant characterics. Key words:Peri-implantitis, treatment, decontamination, implant surface, laser. PMID:23986023

Buitrago-Vera, Pedro; Solá-Ruiz, María F.; Ferrer-García, Juan C.

2013-01-01

374

Effect of Platelet-Rich-Plasma (PRP) and Implant Surface Topography on Implant Stability and Bone  

PubMed Central

Purpose: To evaluate the effect of Platelet-Rich-Plasma (PRP) and different implant surface topography on implant stability and bone levels around immediately loaded dental implants. Materials and Methods: Dental implants were placed in subjects divided into two groups and four subgroups on basis of implant treatment with PRP and implant surface topography used. A total of 30 implants were placed, 15 in each group. For PRP group, implants were placed after surface treatment with PRP. Temporization was done within two weeks and final prosthesis was given after three months. Implant stability was measured with Periotest at baseline, one month and three months. Bone height was measured on mesial & distal side on standardized IOPA x-rays. Results: A statistically significant difference was noticed in implant stability with PRP at baseline. The effect of PRP on bone height changes was not statistically significant. A synergistic effect of PRP and square thread-form was observed on improved implant stability and bone levels; however, no such effect is seen with PRP and reverse buttress thread-form. Conclusion: Within the limitation of this study, enhancement on implant stability and bone healing was observed with PRP treated implant surfaces, and with use of implant with square thread-form. PMID:25121060

Kundu, Renu

2014-01-01

375

Does the number of implants have any relation with peri-implant disease?  

PubMed Central

Objective The aim of this study was to evaluate the relationship between the number of pillar implants of implant-supported fixed prostheses and the prevalence of periimplant disease. Material and Methods Clinical and radiographic data were obtained for the evaluation. The sample consisted of 32 patients with implant-supported fixed prostheses in function for at least one year. A total of 161 implants were evaluated. Two groups were formed according to the number of implants: G1) ?5 implants and G2) >5 implants. Data collection included modified plaque index (MPi), bleeding on probing (BOP), probing depth (PD), width of keratinized mucosa (KM) and radiographic bone loss (BL). Clinical and radiographic data were grouped for each implant in order to conduct the diagnosis of mucositis or peri-implantitis. Results Clinical parameters were compared between groups using Student's t test for numeric variables (KM, PD and BL) and Mann-Whitney test for categorical variables (MPi and BOP). KM and BL showed statistically significant differences between both groups (p<0.001). Implants from G1 – 19 (20.43%) – compared with G2 – 26 (38.24%) – showed statistically significant differences regarding the prevalence of peri-implantitis (p=0.0210). Conclusion It seems that more than 5 implants in total fixed rehabilitations increase bone loss and consequently the prevalence of implants with periimplantitis. Notwithstanding, the number of implants does not have any influence on the prevalence of mucositis.

PASSONI, Bernardo Born; DALAGO, Haline Renata; SCHULDT FILHO, Guenther; OLIVEIRA DE SOUZA, João Gustavo; BENFATTI, César Augusto Magalhães; MAGINI, Ricardo de Souza; BIANCHINI, Marco Aurélio

2014-01-01

376

Nanoporous inorganic membranes or coatings for sustained drug delivery in implantable devices.  

PubMed

The characteristics of nanoporous inorganic coatings on implants or on implantable devices are reviewed. The commonly used nanoporous materials, such as aluminum oxide (Al(2)O(3)), titanium oxide (TiO(2)) and porous silicon are highlighted with illustrative examples. The critical issues for sustained release systems are examined and the elution profiles of nanoporous coatings are discussed. The available data shows that these systems can be used effectively for sustained release applications. They satisfy the basic biocompatibility tests, meet the requirements of drug loading and sustained release profiles extending to several weeks and also are compatible with current implant technologies. Nanoporous inorganic coatings are well suited to provide improved efficacy and integration of implants in a variety of therapeutic situations. PMID:19922749

Gultepe, Evin; Nagesha, Dattatri; Sridhar, Srinivas; Amiji, Mansoor

2010-03-01

377

Formation of Wear Resistant Steel Surfaces by Plasma Immersion Ion Implantation  

SciTech Connect

Plasma immersion ion implantation (PIII) is a versatile and fast method for implanting energetic ions into large and complex shaped three-dimensional objects where the ions are accelerated by applying negative high voltage pulses to a substrate immersed in a plasma. As the line-of-sight restrictions of conventional implanters are circumvented, it results in a fast and cost-effective technology. Implantation of nitrogen at 30 - 40 keV at moderate temperatures of 200 - 400 deg. C into steel circumvents the diminishing thermal nitrogen activation encountered, e.g., in plasma nitriding in this temperature regime, thus enabling nitriding of additional steel grades. Nitride formation and improvement of the mechanical properties after PIII are presented for several steel grades, including AISI 316Ti (food industry), AISI D2 (used for bending tools) and AISI 1095 (with applications in the textile industry)

Maendl, S.; Rauschenbach, B. [Institute fuer Oberflaechenmodifizierung, 04303 Leipzig (Germany)

2003-08-26

378

A wireless implantable sensor network system for in vivo monitoring of physiological signals.  

PubMed

A wireless implantable sensor network system (WISNS) is designed for in vivo monitoring physiological signals of a population of animals. WISNS can simultaneously monitor more than 15 animals, communicating three kinds of analog information among sensor nodes. Analog signals are transmitted to relay node at 800-KHz carrier by AM. Relay nodes digitalize and package them into messages, and then forward to the Wireless sensor network by Nordic RF technology (NWSN). Smaller overall dimensions (<2 cm (3)), lower power regulation, and dedicated packaging make the system suitable and compatible for implantable devices. The implantable sensor node, protocol stack of NWSN, and performance of the system are evaluated and optimized with ECG monitoring test of rats. Compared with those commercially available sensor nodes, our implantable one is leading in the weight and volume miniaturization, and our WISNS solution shows huge potential in achieving the compatibility of different animals. PMID:21536536

Fu, Xiuquan; Chen, Weihong; Ye, Shuming; Tu, Yuewen; Tang, Yawei; Li, Dingli; Chen, Hang; Jiang, Kai

2011-07-01

379

Cochlear implants: a remarkable past and a brilliant future  

PubMed Central

The aims of this paper are to (i) provide a brief history of cochlear implants; (ii) present a status report on the current state of implant engineering and the levels of speech understanding enabled by that engineering; (iii) describe limitations of current signal processing strategies and (iv) suggest new directions for research. With current technology the “average” implant patient, when listening to predictable conversations in quiet, is able to communicate with relative ease. However, in an environment typical of a workplace the average patient has a great deal of difficulty. Patients who are “above average” in terms of speech understanding, can achieve 100% correct scores on the most difficult tests of speech understanding in quiet but also have significant difficulty when signals are presented in noise. The major factors in these outcomes appear to be (i) a loss of low-frequency, fine structure information possibly due to the envelope extraction algorithms common to cochlear implant signal processing; (ii) a limitation in the number of effective channels of stimulation due to overlap in electric fields from electrodes, and (iii) central processing deficits, especially for patients with poor speech understanding. Two recent developments, bilateral implants and combined electric and acoustic stimulation, have promise to remediate some of the difficulties experienced by patients in noise and to reinstate low-frequency fine structure information. If other possibilities are realized, e.g., electrodes that emit drugs to inhibit cell death following trauma and to induce the growth of neurites toward electrodes, then the future is very bright indeed. PMID:18616994

Wilson, Blake S.; Dorman, Michael F.

2013-01-01

380

Development of batteries for implantable applications  

NASA Astrophysics Data System (ADS)

Neuroprosthetic devices that electrically stimulate paralyzed muscles require implantable power sources with exceptional cycle life, safety, and sufficient energy and power density. Of the rechargeable battery technologies, lithium ion batteries have the highest energy density; however, they have limited cycle life of about 1000 cycles. Nickel-hydrogen batteries, currently used in space applications are remarkable for long cycle life (40,000) and low maintenance; however they utilize high hydrogen pressures (60 atm) making them unsuitable for implantable applications. The present work involves design and development of low pressure nickel-hydrogen batteries (1 atm) by utilizing a metal hydride (MH) to store hydrogen, rather than as a negative electrode in the nickel-metal hydride battery. A method to increase the exchange current density of the negative platinum electrode using cyclic voltammetry was developed. A nickel mesh was chosen as the current collector because of its low resistance and stability in alkaline solutions. The tested separators, zirconium oxide and polypropylene, were not significantly different from each other. A pasted type nickel hydroxide electrode was fabricated by two means: screen printing and spatula pressing. The mechanism of electrode formation, the effect of different formation rates with and without overcharge and the effect of binder and nickel content on utilization were studied. Addition of filamentary nickel to the electrode increases the utilization by 10% by decreasing the oxygen evolution. A low pressure nickel-hydrogen battery with and without MH was assembled. Charge and pressure data were analyzed to study the oxygen evolution, the recombination reaction and the self discharge of the cell. Oxygen evolution increases with the depth of charge; however the evolved oxygen recombines completely---70% during charging and the remainder during the first hour of the rest period. About 40-45% hydrogen from the metal hydride was used as fuel during cycling. The pressure composition isotherm was used to estimate the state of charge and to fuel gauge the cell. The NM is deactivated when exposed to KOH solution, increasing the hydrogen equilibration time. Of the tested implantable lithium ion cells, Quallion outperformed the Wilson Greatbatch cells in cycle life. The conditions for maximum cycle life were determined.

Purushothaman, Bushan Kumar

381

The implications of megatrends in information and communication technology and transportation for changes in global physical activity.  

PubMed

Physical inactivity accounts for more than 3 million deaths per year, most from non-communicable diseases in low-income and middle-income countries. We used reviews of physical activity interventions and a simulation model to examine how megatrends in information and communication technology and transportation directly and indirectly affect levels of physical activity across countries of low, middle, and high income. The model suggested that the direct and potentiating eff ects of information and communication technology, especially mobile phones, are nearly equal in magnitude to the mean eff ects of planned physical activity interventions. The greatest potential to increase population physical activity might thus be in creation of synergistic policies in sectors outside health including communication and transportation. However, there remains a glaring mismatch between where studies on physical activity interventions are undertaken and where the potential lies in low-income and middle-income countries for population-level effects that will truly affect global health. PMID:22818940

Pratt, Michael; Sarmiento, Olga L; Montes, Felipe; Ogilvie, David; Marcus, Bess H; Perez, Lilian G; Brownson, Ross C

2012-07-21

382

[Research on the development of image guided oral implant system].  

PubMed

In this paper is introduced an image guided oral implant system (IGOIS), including the 3D surface-model generation through Marching Cubes algorithm and large-scale triangular mesh simplification, the realization of pre-operative planning module with computer graphics and image processing technology, the non-invasive point-to-point registration with the fabrication of tooth-supported polymer resin templates and ICP algorithm, and the development of the real-time navigation system software by programming in VTK and VC+ +6.0. The experimental test for a patient's rapid prototype model shows that with the support of IGOIS, the precision achieved in the planning phase can be transferred to the patient so that the accuracy of the oral implant surgery under difficult conditions is improved. PMID:18610636

Chen, Xiaojun; Lin, Yanping; Wu, Yiqun; Wang, Chengtao

2008-04-01

383

The Responsivity of a Miniaturized Passive Implantable Wireless Pressure Sensor  

PubMed Central

A miniature batteryless implantable wireless pressure sensor that can be used deep inside the body is desired by the medical community. MEMS technology makes it possible to achieve high responsivity that directly determines the operating distance between a miniature implanted sensor and the external RF probe, while providing the read-out. In this paper, for the first time, an analytical expression of the system responsivity versus the sensor design is derived using an equivalent circuit model. Also, the integration of micro-coil inductors and pressure sensitive capacitors on a single silicon chip using MEMS fabrication techniques is demonstrated. Further, the derived analytical design theory is validated by the measured responsivity of these sensors. PMID:25309965

Jiang, Hao; Lan, Di; Goldman, Ken; Etemadi, Mozziyar; Shahnasser, Hamid; Roy, Shuvo

2011-01-01

384

Defects in Ultra-Thin Oxygen Implanted Silicon-on-Insulator Materials  

NASA Astrophysics Data System (ADS)

Dielectric isolation of the active components in integrated circuits becomes increasingly important as silicon devices are scaled down into the submicron regime. In their fabrication, silicon-on-insulator (SOI) substrates have many advantages over bulk silicon substrates, including low power consumption, and greater packing densities of device components. Of the several SOI technologies, the most advanced is the synthesis of a buried oxide layer (BOX) by an oxygen implantation technique that is called SIMOX (Separation by Implantation of Oxygen). Two major processing steps in creating SIMOX are (1) implantation of oxygen and (2) high temperature annealing to restore the crystalline order from the implantation damage. Conventional SIMOX material has top silicon and BOX layers of 200nm and 400nm thickness, respectively. The dimensions of the stack can be adjusted by variation of the process parameters since the thickness of the buried oxide layer depends on the dose of oxygen ions implanted, and that of the top silicon layer on the implantation energy. In recent developments, implantation dose and energy have been reduced, resulting in ultra-thin layers that offer cost savings and improved performance of the SIMOX substrate. However, the smaller dimensions one fifth that of conventional SIMOX - present several challenges since defects and interfaces are much closer to the surface, and slight variations of processing parameters can be detrimental to the final products. Our study investigates various types of defects generated by implantation and their evolution through the intermediate temperature and high temperature annealing. The defects include multiple stacking faults, oxide precipitates, and silicon islands. Their growth, characteristics, and density as a function of implantation energy, oxygen dose, annealing temperature, and time will be discussed.

Seraphin, Supapan; Jeoung, Jun Sik; Johnson, Benedict

2001-11-01

385

Cochlear Implant Using Neural Prosthetics  

NASA Astrophysics Data System (ADS)

This research is based on neural prosthetic device. The oldest and most widely used of these electrical, and often computerized, devices is the cochlear implant, which has provided hearing to thousands of congenitally deaf people in this country. Recently, the use of the cochlear implant is expanding to the elderly, who frequently suffer major hearing loss. More cutting edge are artificial retinas, which are helping dozens of blind people see, and ìsmartî artificial arms and legs that amputees can maneuver by thoughts alone, and that feel more like real limbs.Research, which curiosity led to explore frog legs dancing during thunderstorms, a snail shapedorgan in the inner ear, and how various eye cells react to light, have fostered an understanding of how to ìtalkî to the nervous system. That understanding combined with the miniaturization of electronics and enhanced computer processing has enabled prosthetic devices that often can bridge the gap in nerve signaling that is caused by disease or injury.

Gupta, Shweta; Singh, Shashi kumar; Dubey, Pratik Kumar

2012-10-01

386

Saline breast implant fill issues.  

PubMed

Plastic surgeons' primary responsibility to patients is to inform them sufficiently to permit them to make the necessary decisions in the manner that best meets their own objectives. This makes adequate consultation a lengthy and often confusing experience for patients. One of the most confusing of these is also one of the most mandatory for discussion; that is, the issue of implant fill volume. A patient should be free to choose between an implant that must be overfilled to achieve the optimum, and one in which reaching the optimum does not require overfill or even staying within the manufacturers suboptimal fill volume. The patient must be explicitly informed of the consequences of each of these decisions and should be prepared to sign whichever consents are necessary to reflect her understanding of the compromises involved in any of these choices. PMID:11471954

Dowden, R V

2001-07-01

387

Implant-assisted complete prostheses.  

PubMed

The current review was undertaken to obtain a better understanding of the knowledge base of implant-assisted complete dental prostheses (fixed and removable) in the treatment of the completely edentulous maxilla or mandible. Indications, advantages and disadvantages, complications and maintenance issues, as well as the cost-effectiveness of both treatments, are discussed to help clinicians in their therapeutic decision-making. In summary, when indicated and depending on the patients' needs, both removable and fixed implant-assisted prostheses are highly safe, reliable and satisfactory treatment modalities for the rehabilitation of edentulous jaws. Careful and precise treatment planning is highly recommended to assist the clinician in preventing potential prosthetic failures. The review also reveals that there is still a need for data, generated using robust research methods, on some patient-based and clinical outcomes. PMID:25123765

Emami, Elham; Michaud, Pierre-Luc; Sallaleh, Imad; Feine, Jocelyne S

2014-10-01

388

Short dental implants: a systematic review.  

PubMed

Growing evidence has suggested the utility of short dental implants for oral reconstructive procedures in clinical situations of limited vertical bone height. The aim of this review was to systematically evaluate clinical studies of implants < 10 mm in length, to determine short implant-supported prosthesis success in the atrophic jaw. Implant survival, incidence of biological and biomechanical complications, and radiographic peri-implant marginal bone loss were evaluated. Screening of eligible studies, quality assessment, and data extraction were conducted by two reviewers independently. Meta-analyses were performed by the pooling of survival data by implant surface, surgical technique, implant location, type of edentulism, and prosthetic restoration. Two randomized controlled trials and 14 observational studies were selected and analyzed for data extraction. In total, 6193 short-implants were investigated from 3848 participants. The observational period was 3.2 ± 1.7 yrs (mean ± SD). The cumulative survival rate (CSR) was 99.1% (95%CI: 98.8-99.4). The biological success rate was 98.8% (95%CI: 97.8-99.8), and the biomechanical success rate was 99.9% (95%CI: 99.4-100.0). A higher CSR was reported for rough-surfaced implants. The provision of short implant-supported prostheses in patients with atrophic alveolar ridges appears to be a successful treatment option in the short term; however, more scientific evidence is needed for the long term. PMID:22034499

Annibali, S; Cristalli, M P; Dell'Aquila, D; Bignozzi, I; La Monaca, G; Pilloni, A

2012-01-01

389

Cochlear Implantation in Unique Pediatric Populations  

PubMed Central

Purpose of review Over the last decade, the selection criteria for cochlear implantation have expanded to include children with special auditory, otologic, and medical problems. Included within this expanded group of candidates are those children with auditory neuropathy spectrum disorder, cochleovestibular malformations, cochlear nerve deficiency, associated syndromes, as well as multiple medical and developmental disorders. Definitive indications for cochlear implantation in these unique pediatric populations are in evolution. This review will provide an overview of managing and habilitating hearing loss within these populations with specific focus on cochlear implantation as a treatment option. Recent findings Cochlear implants have been successfully implanted in children within unique populations with variable results. Evaluation for cochlear implant candidacy includes the core components of a full medical, audiologic, and speech and language evaluations. When considering candidacy in these children, additional aspects to consider include disorder specific surgical considerations and child/care-giver counseling regarding reasonable post-implantation outcome expectations. Summary Cochlear implantations are accepted as the standard of care for improving hearing and speech development in children with severe to profound hearing loss. However, children with sensorineural hearing loss who meet established audiologic criteria for cochlear implantation may have unique audiologic, medical, and anatomic characteristics that necessitate special consideration regarding cochlear implantation candidacy and outcome. Individualized pre-operative candidacy and counseling, surgical evaluation, and reasonable post-operative outcome expectations should be taken into account in the management of these children. PMID:23128686

Hang, Anna X.; Kim, Grace G.; Zdanski, Carlton J.

2012-01-01

390

Implantable telemetry for small animals  

NASA Technical Reports Server (NTRS)

A series of totally implantable telemetry devices for use in measuring deep body parameters in small animals were developed. Under a collaborative agreement with NASA, several of these systems; the continuous wave Doppler ultrasonic flowmeter, the multichannel telemetry system, and the inductively-powered dual channel cardiac pacer were evaluated in a series of ten mongrel dogs (15 to 20 kg.). These systems were used to measure ascending aortic and coronary blood flow, aortic pressure, and subcutaneous EKG.

1982-01-01

391

Implantable telemetry for small animals  

NASA Astrophysics Data System (ADS)

A series of totally implantable telemetry devices for use in measuring deep body parameters in small animals were developed. Under a collaborative agreement with NASA, several of these systems; the continuous wave Doppler ultrasonic flowmeter, the multichannel telemetry system, and the inductively-powered dual channel cardiac pacer were evaluated in a series of ten mongrel dogs (15 to 20 kg.). These systems were used to measure ascending aortic and coronary blood flow, aortic pressure, and subcutaneous EKG.

1982-03-01

392

Carbon nanotubes for orthopaedic implants  

Microsoft Academic Search

The physical and biological limitations of current orthopaedic implant materials are a major challenge for bone tissue engineering.\\u000a Nanotechnology has introduced new materials and methods for meeting this challenge. The application of nanotechnology to engineering\\u000a new bone substitutes finds a model in the nanoscale components of natural bone tissue. Carbon nanotubes are a macromolecular\\u000a form of carbon with exceptional properties

Rose L. Spear; Ruth E. Cameron

2008-01-01

393

Low-Noise Implantable Electrode  

NASA Technical Reports Server (NTRS)

New implantable electrocardiogram electrode much less sensitive than previous designs to spurious biological potentials. Designed in novel "pocket" configuration, new electrode is intended as sensor for radiotelemetry of biological parameters in experiments on unrestrained subjects. Electrode is esentially squashed cylinder that admits body fluid into interior. Cylinder and electrical lead are made of stainless steel. Spot welding and crimping are used for assembly, rather than soldering.

Lund, G. F.

1982-01-01

394

Tunable retina encoders for retina implants: why and how.  

PubMed

Current research towards retina implants for partial restoration of vision in blind humans with retinal degenerative dysfunctions focuses on implant and stimulation experiments and technologies. In contrast, our approach takes the availability of an epiretinal multi-electrode neural interface for granted and studies the conditions for successful joint information processing of both retinal prosthesis and brain. Our proposed learning retina encoder (RE) includes information processing modules to simulate the complex mapping operation of parts of the 5-layered neural retina and to provide an iterative, perception-based dialog between RE and human subject. Alternative information processing technologies in the learning RE are being described, which allow an individual optimization of the RE mapping operation by means of iterative tuning with learning algorithms in a dialog between implant wearing subject and RE. The primate visual system is modeled by a retina module (RM) composed of spatio-temporal (ST) filters and a central visual system module (VM). RM performs a mapping 1 of an optical pattern P1 in the physical domain onto a retinal output vector R1(t) in a neural domain, whereas VM performs a mapping 2 of R1(t) in a neural domain onto a visual percept P2 in the perceptual domain. Retinal ganglion cell properties represent non-invertible ST filters in RE, which generate ambiguous output signals. VM generates visual percepts only if the corresponding R1(t) is properly encoded, contains sufficient information, and can be disambiguated. Based on the learning RE and the proposed visual system model, a novel retina encoder (RE*) is proposed, which considers both ambiguity removal and miniature eye movements during fixation. Our simulation results suggest that VM requires miniature eye movements under control of the visual system to retrieve unambiguous patterns P2 corresponding to P1. For retina implant applications, RE* can be tuned to generate optimal ganglion cell codes for epiretinal stimulation. PMID:15876659

Eckmiller, Rolf; Neumann, Dirk; Baruth, Oliver

2005-03-01

395

Tunable retina encoders for retina implants: why and how  

NASA Astrophysics Data System (ADS)

Current research towards retina implants for partial restoration of vision in blind humans with retinal degenerative dysfunctions focuses on implant and stimulation experiments and technologies. In contrast, our approach takes the availability of an epiretinal multi-electrode neural interface for granted and studies the conditions for successful joint information processing of both retinal prosthesis and brain. Our proposed learning retina encoder (RE) includes information processing modules to simulate the complex mapping operation of parts of the 5-layered neural retina and to provide an iterative, perception-based dialog between RE and human subject. Alternative information processing technologies in the learning RE are being described, which allow an individual optimization of the RE mapping operation by means of iterative tuning with learning algorithms in a dialog between implant wearing subject and RE. The primate visual system is modeled by a retina module (RM) composed of spatio-temporal (ST) filters and a central visual system module (VM). RM performs a mapping 1 of an optical pattern P1 in the physical domain onto a retinal output vector R1(t) in a neural domain, whereas VM performs a mapping 2 of R1(t) in a neural domain onto a visual percept P2 in the perceptual domain. Retinal ganglion cell properties represent non-invertible ST filters in RE, which generate ambiguous output signals. VM generates visual percepts only if the corresponding R1(t) is properly encoded, contains sufficient information, and can be disambiguated. Based on the learning RE and the proposed visual system model, a novel retina encoder (RE*) is proposed, which considers both ambiguity removal and miniature eye movements during fixation. Our simulation results suggest that VM requires miniature eye movements under control of the visual system to retrieve unambiguous patterns P2 corresponding to P1. For retina implant applications, RE* can be tuned to generate optimal ganglion cell codes for epiretinal stimulation.

Eckmiller, Rolf; Neumann, Dirk; Baruth, Oliver

2005-03-01

396

Neural control of cursor trajectory and click by a human with tetraplegia 1000 days after implant of an intracortical microelectrode array  

E-print Network

Neural control of cursor trajectory and click by a human with tetraplegia 1000 days after implant of cursor trajectory and click by a human with tetraplegia 1000 days after implant of an intracortical assistive technologies such as computers and robotic assistive devices, or to enable functional electrical

Black, Michael J.

397

Assessment of interleukin-1beta and interleukin-6 in the crevicular fluid around healthy implants, implants with peri-implantitis, and healthy teeth: a cross-sectional study  

PubMed Central

Objectives This study aimed to assess and compare the levels of interleukin-1beta (IL-1?) and interleukin-6 (IL-6) in the crevicular fluid around healthy implants, implants with peri-implantitis, and healthy teeth. Materials and Methods This study evaluated 16 dental implants in 8 patients (4 males and 4 females). These patients had at least one healthy implant and one implant with peri-implantitis next to healthy teeth. The crevicular fluid was collected using absorbent cones and transferred to the laboratory. Specimens were evaluated by ELISA for interleukin levels. Data were analyzed using repeated measures ANOVA and Bonferroni tests (P<0.05). Results Levels of IL-1? in the crevicular fluid around implants with peri-implantitis were significantly higher than around healthy implants (P=0.002); the latter was significantly higher than around healthy teeth (P=0.015). A significant difference was found in the level of IL-6 in the crevicular fluid around implants with peri-implantitis and healthy implants (P=0.049) and also between implants with peri-implantitis and healthy teeth (P<0.001). Conclusion Within the limitations of this study, significant differences exist in the levels of IL-1? and IL-6 in the crevicular fluid of implants with peri-implantitis, healthy implants, and healthy teeth. More studies with larger sample sizes in different populations are necessary. PMID:25368834

Yaghobee, Siamak; Khorsand, Afshin; Rasouli Ghohroudi, Amir Alireza; Sanjari, Khashayar

2014-01-01

398

Immediate implants in anterior maxillary arch  

PubMed Central

Aim: The aim of the study was to evaluate the osseo-integration and soft tissue status of the endosseous implants placed in immediate extraction socket. Methodology: Seven patients (4 males and 3 females) aged 20-30 years were selected for the study. Nine implants were placed in seven patients in the maxillary arch. All the patients were clinically ?nd thoroughly examined. Under local anesthesia, the indicated tooth was extracted. The extracted socket was prepared using standard drills with palatal wall as guide. The longest and widest implants were placed (Hi-Tec Implants). All implants showed good primary stability. The implants used in the study were tapered design endosseous implants with Threaded implants (TI) unit plasma-sprayed surface. Surgical re-entry (secondary surgery) was performed to remove the healing cap after 6 months for supra crestal fabrication. All patients were reviewed periodically at 3rd and 6th month interval and the following clinical parameters including modified plaque index (mPlI), modified bleeding index (mBI), probing depth (PD), attachment level (AL), and distance between the implant shoulder and mucosal margin (DIM), distance between the implant shoulder and first bone-implant contact, and Clinical Mobility Index were recorded. The results were computed and subjected to statistical evaluation. Results: The mPlI, mBI, PD, AL, and DIM were evaluated around the implants at baseline, 3rd and 6th month intervals and analyzed statistically by Friedman T-test. The results of the above were shown to be statistically non-significant. The distance between the implant shoulder and first bone implant contact was evaluated around the implants at base line, 3rd and 6th month intervals. The results proved to be statistically significant (0.01) implying that there was a bone apposition around the implants. Conclusion: During the course of the study, soft tissue status around implants was found to be healthy. Osseointegration as assessed by clinical and radiographic findings was found to be sound. PMID:24678203

Anitha, K.; Kumar, S. Senthil; Babu, M. R. Ramesh; Candamourty, Ramesh; Thirumurugan

2014-01-01

399

Potential Applications USC Technology Opportunity  

E-print Network

with autoimmune and inflammatory diseases. · Decreases immune response, acting as an anti-inflammatory agent · Treats various autoimmune diseases without invoking psychotropic e ects · May be administered-inflammatory agent, and treat various autoimmune diseases without invoking the psychotropic e ects of THC

Almor, Amit

400

Terrestrial applications from space technology  

NASA Technical Reports Server (NTRS)

NASA's Technology Utilization Program, which is concerned with transferring aerospace technologies to the public and private sectors, is described. The strategy for transferring the NASA technologies to engineering projects includes: (1) identification of the problem, (2) selection of an appropriate aerospace technology, (3) development of a partnership with the company, (4) implementation of the project, and (5) commercialization of the product. Three examples revealing the application of aerospace technologies to projects in biomedical engineering, materials, and automation and robotics are presented; the development of a programmable, implantable medication system and a programmable, mask-based optical correlator, and the improvement of heat and erosion resistance in continuous casting are examined.

Clarks, H.

1985-01-01

401

Dental implant installation without antibiotic prophylaxis.  

PubMed

The objective of this study was to retrospectively compare the outcomes of dental implant treatment with and without antibiotic prophylaxis. Two groups of patients with edentulous or partially edentulous maxillas or mandibles (or both) were treated with dental implants. One group, consisting of 147 patients (790 implants), was given prophylaxis with oral phenoxymethylpenicillin; 1 g of antibiotic was administered 1 hour preoperatively, and 1 g was administered every 8 hours for 10 days postoperatively. The other group, consisting of 132 patients (664 implants) was not given any antibiotics preoperatively or postoperatively. There were no significant differences with respect to early and late postoperative infections or with respect to implant survival between the two groups. It appears that antibiotic prophylaxis for routine dental implant surgery offers no advantage for the patient. PMID:9619664

Gynther, G W; Köndell, P A; Moberg, L E; Heimdahl, A

1998-05-01

402

Nasal reconstruction using porous polyethylene implants.  

PubMed

Nasal reconstruction presents a significant challenge to the facial plastic surgeon. The dual goals of reconstruction are restoration of the desired aesthetic nasal contour and an improved nasal airway. Autologous cartilage and bone are considered optimal grafting material, but their supply is often limited and harvesting entails additional morbidity. Many synthetic materials have been introduced in nasal reconstruction, but high infection and extrusion rates limited their use. Porous high density polyethylene implants present an alternative to autologous material as they allow for fibrovascular ingrowth, leading to stability of the implant and decreased rates of infection. Herein we describe the use of porous high density polyethylene implants for reconstruction of the platyrrhine nose and in revision rhinoplasty. The use of preformed nasal-dorsal tip and alar batten implants are described, as well as the use of columellar strut and premaxillary plumper implants. We believe that porous high density polyethylene implants provide a safe, desirable alternative in functional and aesthetic nasal reconstruction. PMID:11802347

Romo, T; Sclafani, A P; Jacono, A A

2000-01-01

403

Iron implantation in ?-Al2O3  

Microsoft Academic Search

Single crystal and ceramic ?-Al2O3 samples were implanted with 57Fe ions at different fluences, and different charge states of Fe were determined. The hyperfine interaction data showed that implanted ions are in Fe0, Fe2+, and Fe3+ states depending on the fluence. It is shown that after the annealing of the implanted sample in a 2.5CO 1CO2 atmosphere Fe spinel forms.

I. De´zsi; Cs. Fetzer

2008-01-01

404

Calf augmentation with new solid silicone implants  

Microsoft Academic Search

Calf augmentation has been standardized by the use of banana-shaped silicone gel implants for almost 20 years. Capsule formation and resulting distignement, dislocation, gel bleeding, and implant rupture are rare but unpleasant complications. A new implant of solid silicone (McGhan, Santa Barbara, CA, USA) in the anatomical shape of one belly of theM. gastrocnemius placed subfascially appears to overcome these

Gottfried Lemperle; Karlheinz Kostka

1993-01-01

405

Highly Accurate CAD Tools for Cranial Implants  

Microsoft Academic Search

\\u000a Prefabricated patient-specific cranial implants are especially useful for large cranial defects. We present CAD tools for\\u000a large cranial implants that include validation of fit prior to rapid prototype fabrication. Our CAD process first determines\\u000a whether the prototype implant surface intersects adjacent soft-tissue structures via collision detection. If so, we measure\\u000a the volume of both the intersected dura and unoccupied area

Kyoung-june Min; David Dean

2003-01-01

406

Focused phosphorus ion beam implantation into silicon  

Microsoft Academic Search

Phosphorus implantation into (100) silicon using a 32-keV focused ion beam is investigated from the standpoints of electrical properties and damage to the implanted layers. Phosphorus ions are extracted from the Pt-P-Sb alloy liguid-metal-ion source. Electrical properties are measured by isochronal annealing with Hall measurements and radiation damage is evaluated using a transmission electron microscope. Compared with the conventional implantation

Y. Madokoro; S. Shukuri; K. Umemura; M. Tamura

1989-01-01

407

Procedures for radioactive I-125 seed implants  

SciTech Connect

Typical safety procedures and guidelines for the use of radioactive I-125 seed implant are presented. Topics covered include: Physical properties, management and planning of I-125, source logging, source transportation, source accounting during and after implant, room monitoring, recording, dosimetry films, nursing procedures, discharge of patient. These guidelines have been found to be of practical value for personnel involved with the implant to ensure compliance with the regulations, but are not necessarily the only procedures that could be utilized.

Sharma, S.C. (Univ. of Louisville, KY (USA))

1988-12-01

408

Breast Implant Stability in the Subfascial Plane and the New Shaped Silicone Gel Breast Implants  

Microsoft Academic Search

The author presents his experience with breast augmentation using a next-generation, form-stable, anatomically shaped silicone\\u000a gel breast implant. Rotation is a potential complication for anatomically shaped breast implants. Anatomically shaped saline\\u000a implants have been reported to have a rotation rate as high as 14%, while lower rotation rates of 1–2.6% for anatomic cohesive\\u000a gel silicone implants have been reported. Currently,

João Carlos Sampaio Góes; Sampaio Goes

2010-01-01

409

Synthesis of unattainable ion implantation profiles — 'Pseudo-implantation'  

NASA Astrophysics Data System (ADS)

Metal implantation provides a powerful tool for the formation of non-equilibrium alloy layers for a wide variety of basic and applied materials applications, but the technique is fundamentally limited in two important ways: (i) the implanted species concentration is limited by sputtering of the modified layer by the incident ion beam itself, and the sputter-limited retained dose is often disappointingly low; (ii) the thickness of the modified layer is limited by the maximum ion energy available, and for practical reasons (implanter voltage) the layer thickness is often just a few hundred ångströms. We describe here a metal-plasma-immersion-based method for synthesizing non-equilibrium alloy layers of arbitrarily high dopant concentration and of arbitrary thickness. By repetitively pulse biasing the substrate to high negative voltage while it is immersed in the metal plasma from a vacuum arc plasma gun, a layer can be synthesized that is atomically mixed into the substrate with an interface width determined by the early-time bias voltage and with a thickness determined by the overall duration of the process. The species is that of the vacuum arc cathode material, which for this purpose can be a mixture of the substrate metal and the wanted dopant metal. We have used the method to form a high concentration Ta layer on the copper rails of an electromagnetic rail gun, with total surface area treated about 3000 cm 2; the Ta depth profile was flat at about 50 at.% Ta in Cu to a depth of about 1000 Å.

Brown, I. G.; Anders, A.; Anders, S.; Castro, R. A.; Dickinson, M. R.; MacGill, R. A.; Wang, Z.

1995-12-01

410

Fig. 1. (a) Cochlea implant system and (b) Cochlea anatomy Abstract--Robot-assisted cochlear implant surgery was  

E-print Network

--Robot-assisted cochlear implant surgery was proposed and proved to be efficient in reducing insertion forces on acrylic implant surgeries. I. INTRODUCTION ULTI-CHANNEL cochlear implants have been developed for more than 30 cochlear implant surgery. The cochlear implant system includes a microphone, a micro

Simaan, Nabil

411

Subdural haematoma: a complication of cochlear implantation.  

PubMed

Cochlear implants have transformed the treatment of sensorineural hearing loss. They have few major complications. The authors describe the case of a man fitted with a cochlear implant who suffered a postoperative subdural haematoma. The haematoma is thought to have been caused by bleeding from emissary veins opened by the drill passages used to anchor the sutures for the receiver/stimulator. The authors have abandoned tie down sutures in cochlear implants, preferring an appropriately deep well with squared-off rims, which would secure the implant in place. They have had no further complications of this nature. PMID:15667688

Sunkaraneni, V S; Banerjee, A; Gray, R F

2004-12-01

412

Peri-implantitis: from diagnosis to therapeutics.  

PubMed

Peri-implantitis is an infection of the tissue around an implant, resulting in the loss of supporting bone. Risk factors for peri-implantitis consist of a history of periodontitis, dental plaque, poor oral hygiene, smoking, alcohol consumption and diabetes. A clinical diagnosis indicates inflammatory signs including bleeding on probing with or without suppuration and a peri-implant pocket depth ?5 mm. A radiograph shows images of marginal bone loss ?2 mm. A differential diagnosis of peri-implant mucositis, occlusal overload, retrograde peri-implantitis and inflammatory implant periapical lesions suggests the appropriate treatment in each case. The non-surgical treatment of peri-implantitis, including a mechanical treatment alone or combined with antiseptics or antibiotics can improve clinical parameters in the short term but residual defects may still persist. Surgical treatment such as guided bone regeneration results in a gain of clinical attachment level and bone reconstruction in the long term. The limited effect of laser-assisted therapy needs to be further evaluated. The concept of prevention based on early detection and regular maintenance plays a principal role in reducing the occurrence of peri-implantitis. PMID:22383175

Nguyen-Hieu, Tung; Borghetti, Alain; Aboudharam, Gérard

2012-05-01

413

Levonorgestrel subdermal implants. Contraception on trial.  

PubMed

When they were introduced to the world market in the 1980s, levonorgestrel subdermal implants offered the promise of an exciting alternative to traditional hormonal contraception. They provide highly effective, long-acting protection from pregnancy, without the need for user compliance. Broad acceptability of the drug has been reported throughout the world. Recently, however, the implants have met with opposition. The drug is associated with a variety of adverse effects, and removal of implants can be problematic. Serious events have been reported in women using levonorgestrel subdermal implants, although causal relationships have not been demonstrated. Additionally, concerns have been raised over the potential for coercive use of the drug. Numerous law suits have been filed alleging serious problems with implants. As a result, the drug has received considerable negative media attention. Before the controversy over levonorgestrel subdermal implants erupted, contraceptive development had declined, resulting from limitations to profits and funding, legal threats, and changes in the insurance industry. The levonorgestrel subdermal implant experience may serve to accelerate this trend. While the introduction of levonorgestrel subdermal implants offered an alternative to the current array of medical contraception, its experience may serve to dampen future contraceptive development efforts. Costly litigation and much controversy involving the implants have acted to create disincentives to further research and development of new methods of medical contraception. PMID:9429835

Frank, M L; DiMaria, C

1997-12-01

414

Where the PIP is the implant?  

PubMed

A 51-year-old woman, who had previous breast augmentation and a video-assisted thoracoscopic wedge resection of the lung, underwent breast implant replacement of Poly Implant Protheses (PIP) due to a loss of volume on the right side of the chest. During this procedure, no implant was found in the right subpectoral space; however, a large defect was observed in the fifth intercostal space. A computed tomography scan of the chest indicated a circular entity in the right pleural cavity, which was confirmed to be the lost implant during a subsequent video-assisted thoracoscopic surgery (VATS). PMID:24566062

Bruintjes, Moira H D; Schouten, Corinne; Fabré, Jan; van den Wildenberg, Frits J; Wijnberg, David S

2014-08-01

415

Implanting Beef Calves and Stocker Cattle  

E-print Network

site. Cattle performance Suckling calves: Implanting suck- ling calves once with zeranol or estra- diol-progesterone type implants will in- crease daily weight gains an average of 0.10 pound per day for steer calves and 0.12 pound per day for heifer... site. Cattle performance Suckling calves: Implanting suck- ling calves once with zeranol or estra- diol-progesterone type implants will in- crease daily weight gains an average of 0.10 pound per day for steer calves and 0.12 pound per day for heifer...

McCollum III, Ted

1998-04-24

416

Short implant in limited bone volume.  

PubMed

Rehabilitation of severely resorbed jaws with dental implants remains a surgical and prosthetic challenge for clinicians. The purpose of this review was to evaluate the available data on short-length implants and discuss their indications and limitations in daily clinical practice. A structured review of MEDLINE and a manual search were conducted. Thirty-two case series devoted to short-length implants, 14 reviews and 3 randomized controlled trials were identified. Of this group of papers, we can conclude that short-length implants can be successfully used to support single and multiple fixed reconstructions in posterior atrophied jaws, even in those with increased crown-to-implant ratios. The use of short-length implants allows treatment of patients who are unable to undergo complex surgical techniques for medical, anatomic or financial reasons. Moreover, the use of short-length implants in daily clinical practice reduces the need for complex surgeries, thus reducing morbidity, cost and treatment time. The use of short implants promotes the new concept of stress-minimizing surgery, allowing the surgeon to focus more on the correct three-dimensional positioning of the implant. PMID:25123762

Nisand, David; Renouard, Franck

2014-10-01

417

Capsular bag distention syndrome after combined cataract-lens implant surgery and ahmed valve implantation  

Microsoft Academic Search

PURPOSE: To describe the capsular bag distention syndrome after combined cataract extraction with posterior lens implant and aqueous drainage device.METHODS: Case report.RESULTS: A persistently shallow anterior chamber and low intraocular pressure developed after combined cataract extraction with posterior chamber lens implant and Ahmed aqueous drainage device. An optically empty space between the lens implant and posterior capsule was detected 18

Brent R McQueen; Curtis E Margo

2001-01-01

418

Totally implantable real-time in vivo video telemetry monitoring system for implant biocompatibility studies  

Microsoft Academic Search

An implantable real-time video telemetry monitoring system was developed for remote monitoring and evaluation of tissue reactions to an implant such as a biosensor. Experimental coatings and treatments to improve the function of an implant can now be evaluated in situ and in real-time for improved blood vessel growth (angiogenesis), reduced inflammation, and reduction of foreign body encapsulation. A tissue

Richard D. Beach; Francis Moussy

2001-01-01

419

Possible risks due to exposure of workers and patients with implants by TETRA transmitters.  

PubMed

Several studies have demonstrated that mobile telephones that use different technologies, such as Global System for Mobile Communication (GSM) or Universal Mobile Telecommunication System (UMTS), have the potential to influence the functionality of active electronic implants, including cardiac pacemakers. According to these studies, a few safety measures, such as maintaining minimum distances of 25?cm between implants and transmitters, are sufficient to avoid such effects. Terrestrial Trunked Radio (TETRA) has become a well-established communication standard in many countries, including Germany and Austria. TETRA transmitters are typically used by police forces and emergency services. Employees and volunteers working for such institutions are often in close contact with patients, causing TETRA transmitters to potentially have an impact on the functionality of the implants of patients. Therefore, the main focus of our study was to investigate the functionality of several types of implants when exposed to TETRA transmitters. Moreover, we investigated the difference in the degree of exposure of users of TETRA transmitters when they carry the devices in different locations near the body, and when they use them in different positions near the head. Our results show that a compliance distance of 30?cm between implant and transmitter is sufficient to exclude any influence on the examined implants. All examined exposure conditions demonstrated that the levels were well below recommended limits. If a user wants to minimize their exposure, use of transmitters in front of the mouth leads to somewhat lower exposure when compared to typical mobile phone like use. PMID:24436224

Cecil, Stefan; Neubauer, Georg; Rauscha, Friedrich; Stix, Günter; Müller, Wolfgang; Breithuber, Christian; Glanzer, Markus

2014-04-01

420

The Technology of Hip Replacement  

E-print Network

The Technology of Hip Replacement Between 80 and 90% of hips destroyed by rheumatoid arthritis can hip replacement. P rogressive damage to joints becomes increasingly preva- lent as the population ages be restored to useful function and rendered free of pain by total hip arthroplasty. With more than 100 implant

421

Edinburgh Research Explorer Technology Convergence  

E-print Network

a preliminary exploration of issues around the convergence of several technologies: artificial intelligence otherwise inert artificial intelligence-controlled human being." Just as human zombies are very real,4 so implants). We conclude that there is a need for further and better ­ more "joined-up" ­ regulation

Millar, Andrew J.

422

21 CFR 886.3320 - Eye sphere implant.  

Code of Federal Regulations, 2013 CFR

...8 2013-04-01 2013-04-01 false Eye sphere implant. 886.3320 Section 886...DEVICES Prosthetic Devices § 886.3320 Eye sphere implant. (a) Identification. An eye sphere implant is a device intended to...

2013-04-01

423

21 CFR 886.3320 - Eye sphere implant.  

...8 2014-04-01 2014-04-01 false Eye sphere implant. 886.3320 Section 886...DEVICES Prosthetic Devices § 886.3320 Eye sphere implant. (a) Identification. An eye sphere implant is a device intended to...

2014-04-01

424

21 CFR 886.3320 - Eye sphere implant.  

Code of Federal Regulations, 2010 CFR

...8 2010-04-01 2010-04-01 false Eye sphere implant. 886.3320 Section 886...DEVICES Prosthetic Devices § 886.3320 Eye sphere implant. (a) Identification. An eye sphere implant is a device intended to...

2010-04-01

425

21 CFR 886.3320 - Eye sphere implant.  

Code of Federal Regulations, 2011 CFR

...8 2011-04-01 2011-04-01 false Eye sphere implant. 886.3320 Section 886...DEVICES Prosthetic Devices § 886.3320 Eye sphere implant. (a) Identification. An eye sphere implant is a device intended to...

2011-04-01

426

21 CFR 886.3320 - Eye sphere implant.  

Code of Federal Regulations, 2012 CFR

...8 2012-04-01 2012-04-01 false Eye sphere implant. 886.3320 Section 886...DEVICES Prosthetic Devices § 886.3320 Eye sphere implant. (a) Identification. An eye sphere implant is a device intended to...

2012-04-01

427

21 CFR 872.3645 - Subperiosteal implant material.  

...implant material. (a) Identification. Subperiosteal implant material is a device composed of titanium or cobalt chrome molybdenum intended to construct custom prosthetic devices which are surgically implanted into the lower or upper jaw between...

2014-04-01

428

21 CFR 874.3695 - Mandibular implant facial prosthesis.  

Code of Federal Regulations, 2010 CFR

... false Mandibular implant facial prosthesis. 874.3695 Section 874.3695...3695 Mandibular implant facial prosthesis. (a) Identification. A mandibular implant facial prosthesis is a device that is...

2010-04-01

429

Implant-supported fixed restoration of post-traumatic mandibular defect accompanied with skin grafting: A clinical report  

PubMed Central

Traumatic defects are mostly accompanied by hard and soft tissue loss. This report describes the surgical and prosthetic treatment of a patient with post-traumatic mandibular defect. A split-thickness skin graft was performed prior to implant placement and prefabricated acrylic stent was placed to hold the graft in place. The esthetic and functional demands of the patient were fulfilled by implant-supported screw-retained fixed prosthesis using CAD-CAM technology. PMID:23508120

Noh, Kwantae; Choi, Woo-Jin

2013-01-01

430

Axial relationship between dental implants and teeth/implants: a radiographic study.  

PubMed

The relationship of dental implants with neighboring teeth will affect both occlusal relationship and distribution of forces; thus, the purpose of this study was to examine implants' axial relationship with adjacent and opposing teeth/implants. Data of dental implants patients was retrieved. Panoramic X rays were digitized. Computer-based software was used to measure the angular relationship between the implants and adjacent/opposing teeth and implants. Data was further sorted by the mode of placement and implants position. 50 patients (219 implants) were included. Mean angle to adjacent tooth/implant was 178.71° ± 9.18° (range 129.7°-206°). Implants were more parallel to adjacent teeth (180.99° ± 1.06°) than to adjacent implants (176.32° ± 0.54°; P = .0001). Mean angular relationship to opposite tooth was 167.88° ± 8.92° (range 137.7°-179.8°). Implants that were placed freehand or with positional guide had similar intra-arch relationship (178.22° and 178.81°, respectively) and similar inter-arch angulations (164.46° and 167.74°). Molars had greater deviation of the angular relationship (175.54°) compared to premolars (181.62°) and incisors (180.55°, P = .0001). Implants placed in the maxilla had smaller axial deviation compared to implants in the mandible (180.41° ± 0.64 vs 177.14° ± 1.02; P = .0081). Good axial relationship may be obtained in most implants placed by an experienced clinician, even when placed freehand. The mandibular posterior region is more prone to axial deviation and as such requires special attention. PMID:25106006

Machtei, Eli E; Oettinger-Barak, Orit; Horwitz, Jacob

2014-08-01

431

A multielectrode implant device for the cerebral cortex.  

PubMed

A new class of brain implant technology was developed that allows the simultaneous recording of voltage signals from many individual neurons in the cerebral cortex during cognitive tasks. The device allows recording from 49 independent positions spanning a 2 x 2-mm region of neural tissue. The recording electrodes are positioned in a square grid with 350 microm spacing, and each microelectrode can be precisely independently vertically positioned using a hydraulic microdrive. The device utilizes ultrafine, sharp iridium microelectrodes that minimize mechanical disturbance of the region near the electrode tip and produce low noise neuronal recordings. The total weight of this device is less than 20 g, and the device is reusable. The implant device has been used for transdural recordings in primary somatosensory and auditory cortices of marmosets, owl monkeys, and rats. On a typical day, one-third of the microelectrodes yield well-discriminated single neuron action potential waveforms. Additional array electrodes yield lower amplitude driven multiunit activity. The average signal-to-noise ratio of discriminated action potential waveforms 6 months after implantation was greater than 9. Simple design alternatives are discussed that can increase the number of electrodes in the array and the depths at which dense array recordings can be achieved. PMID:10598862

deCharms, R C; Blake, D T; Merzenich, M M

1999-10-30

432

Surgical management of cardiac implantable electronic device infections  

PubMed Central

Purpose The infection of cardiac implantable electronic devices (CIED) is a serious and potentially lethal complication. The population at risk is growing, as the device implantation is increasing especially in older patients with associated comorbid conditions. Our purpose was to present the management of this complicated surgical condition and to extract the relevant conclusions. Methods During a 3-year period 1,508 CIED were implanted in our hospital. We treated six cases of permanent pacemaker infection with localized pocket infection or endocarditis. In accordance to the recent AHA/ACC guidelines, complete device removal was decided in all cases. The devices were removed under general anaesthesia, with a midline sternotomy, under extracorporeal circulation on the beating heart. Epicardial permanent pacing electrodes were placed on the right atrium and ventricle before the end of the procedure. Results The postoperative course of all patients was uncomplicated and after a follow up period of five years no relapse of infection occurred. Conclusions Management protocols that include complete device removal are the only effective measure for the eradication of CIED infections. Although newer technologies have emerged and specialized techniques of percutaneous device removal have been developed, the surgical alternative to these methods can be a safe solution in cases of infected devices. PMID:24672692

Koutentakis, Michael; Siminelakis, Stavros; Korantzopoulos, Panagiotis; Petrou, Alexandra; Priavali, Eleftheria; Mpakas, Andreas; Gesouli, Eleftheria; Apostolakis, Eleftheria; Tsakiridis, Kosmas; Katsikogiannis, Nikolaos; Kougioumtzi, Ioanna; Machairiotis, Nikolaos; Tsiouda, Theodora; Zarogoulidis, Konstantinos

2014-01-01

433

Energy efficiency and reliability in wireless biomedical implant systems.  

PubMed

The use of wireless implant technology requires correct delivery of the vital physiological signs of the patient along with the energy management in power-constrained devices. Toward these goals, we present an augmentation protocol for the physical layer of the medical implant communications service (MICS) with focus on the energy efficiency of deployed devices over the MICS frequency band. The present protocol uses the rateless code with the frequency-shift keying (FSK) modulation scheme to overcome the reliability and power cost concerns in tiny implantable sensors due to the considerable attenuation of propagated signals across the human body. In addition, the protocol allows a fast start-up time for the transceiver circuitry. The main advantage of using rateless codes is to provide an inherent adaptive duty cycling for power management, due to the flexibility of the rateless code rate. Analytical results demonstrate that an 80% energy saving is achievable with the proposed protocol when compared to the IEEE 802.15.4 physical layer standard with the same structure used for wireless sensor networks. Numerical results show that the optimized rateless coded FSK is more energy efficient than that of the uncoded FSK scheme for deep tissue (e.g., digestive endoscopy) applications, where the optimization is performed over modulation and coding parameters. PMID:21233054

Abouei, Jamshid; Brown, J David; Plataniotis, Konstantinos N Kostas; Pasupathy, Subbarayan

2011-05-01

434

Surface analysis of failed oral titanium implants.  

PubMed

The aim of the present study was to investigate the surface topography, composition, and oxide thickness of consecutively failed, oral Brånemark implants in order to determine possible causes for failure. The failure criterion was lack of osseointegration manifested as implant mobility. Ten implants were retrieved before loading (early failures) and 12 during a period of function up to 8 years (late failures). At retrieval, early losses did not display any clinical sign of infection. All late failures were radiographically characterized by peri-implant radiolucency and did not show infectious signs with one exception. No implant seemed to be lost due to peri-implantitis (plaque-induced progressive marginal bone loss). Twelve implants were analyzed by scanning electron microscopy (SEM), Auger electron spectroscopy (AES), and depth profiling using a blind protocol. Two pristine fixtures, which underwent the same preparation as the failed implants, were used as controls. In the SEM, control samples were essentially free from macroscopic contamination, whereas failed implants contained varying amounts of tissue residues. AES showed that all surfaces consisted of Ti oxide and varying amounts of additional elements, with C dominating in most cases. Nitrogen and sometimes Na, Ca, P, Cl, S, and Si were detected. The Si contamination was most likely due to ion leaching from the glass vials used for storage. Depth profiles showed a typical oxide thickness of 5-8 nm for all samples. In conclusion, no significant changes in the oxide layer composition or thickness as a result of implantation were observed. The results do not indicate any material-related cause for the failures of these implants. Possible reasons for these failures were impaired healing, asymptomatic infection, and overload. PMID:10421701

Esposito, M; Lausmaa, J; Hirsch, J M; Thomsen, P

1999-01-01

435

Ion implanted arsenic in silicon  

NASA Astrophysics Data System (ADS)

The behaviour of high concentration ion implanted arsenic in silicon during high temperature annealing has been studied. It is found that the cooling rate following high temperature anneling has a pronounced effect on the maximum carrier concentration which can be obtained at a given temperature, and it is demonstrated that the equilibrium carrier concentration at a given temperature is higher than the previously accepted value. The anomalous, enhanced diffusion for arsenic concentrations exceeding ˜ 2 × 10 20 cm -3 is successfully modelled within the vacancy-percolation model, and it is concluded that collective phenomena play a significant role in the diffusion at high donor concentrations.

Larsen, Arne Nylandsted; Christensen, Birgit; Christensen, Peter H.; Shiryaev, Sergey Yu.

1993-06-01

436

Bronchoscopic Implantation of a Novel Wireless Electromagnetic Transponder in the Canine Lung: A Feasibility Study  

SciTech Connect

Purpose: The success of targeted radiation therapy for lung cancer treatment is limited by tumor motion during breathing. A real-time, objective, nonionizing, electromagnetic localization system using implanted electromagnetic transponders has been developed (Beacon electromagnetic transponder, Calypso Medical Technologies, Inc., Seattle, WA). We evaluated the feasibility and fixation of electromagnetic transponders bronchoscopically implanted in small airways of canine lungs and compared to results using gold markers. Methods and Materials: After approval of the Animal Studies Committee, five mongrel dogs were anesthetized, intubated, and ventilated. Three transponders were inserted into the tip of a plastic catheter, passed through the working channel of a flexible bronchoscope, and implanted into small airways of a single lobe using fluoroscopic guidance. This procedure was repeated for three spherical gold markers in the opposite lung. One, 7, 14, 28, and 60 days postimplantation imaging was used to assess implant fixation. Results: Successful bronchoscopic implantation was possible for 15 of 15 transponders and 12 of 15 gold markers; 3 markers were deposited in the pleural space. Fixation at 1 day was 15 of 15 for transponders and 12 of 12 for gold markers. Fixation at 60 days was 6 of 15 for transponders and 7 of 12 for gold markers, p value = 0.45. Conclusions: Bronchoscopic implantation of both transponders and gold markers into the canine lung is feasible, but fixation rates are low. If fixation rates can be improved, implantable electromagnetic transponders may allow improved radiation therapy for lung cancer by providing real-time continuous target tracking. Developmental work is under way to improve the fixation rates and to reduce sensitivity to implantation technique.

Mayse, Martin L. [Division of Pulmonary and Critical Care, Washington University School of Medicine, St. Louis, MO (United States); Parikh, Parag J. [Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO (United States)], E-mail: pparikh@radonc.wustl.edu; Lechleiter, Kristen M. [Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO (United States); Dimmer, Steven; Park, Mia [Calypso Medical Technologies, Seattle, WA (United States); Chaudhari, Amir [Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO (United States); Talcott, Michael [Division of Comparative Medicine, Washington University School of Medicine, St. Louis, MO (United States); Low, Daniel A.; Bradley, Jeffrey D. [Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO (United States)

2008-09-01

437

MEAT SCIENCE AND MUSCLE BIOLOGY SYMPOSIUM--implant and beta agonist impacts on beef palatability.  

PubMed

The use of anabolic implants has a long-standing place in the cattle feeding industry, due to their positive impact on growth performance and subsequent profitability. However, implants can have adverse effects on carcass quality, shear force, and eating quality depending on the dose and frequency, or what some refer to as the aggressiveness of the implant regimen administered. Within the past decade, a new class of growth promotants, known as ?-adrenergic agonists (?AA), has emerged in the beef feeding industry in the United States. Currently, 2 have gained U.S. Food and Drug Administration approval for use in beef finishing diets to improve performance and carcass yields. Much like anabolic implants, these repartitioning agents can have negative effects on Warner-Bratzler shear force (WBSF), but the differences do not necessarily translate directly to consumer responses for palatability and acceptance in some instances, especially when tenderness is managed through proper postmortem aging. As researchers continued to investigate the mechanisms responsible for the impact of ?AA, inevitably this led to consideration of the interaction between ?AA and anabolic implants. Early work combining zilpaterol hydrochloride (ZH) with anabolic implants improved performance, carcass yield, and meat yield with additive negative effects on WBSF. Similar results were produced when pairing ZH with anabolic steroids equipped with various release patterns. As with any tool, the key to success is proper management. Certain cattle populations may be better suited to receive growth promotants such as implants and ?AA, and postmortem management of subprimal cuts becomes vital when producers take more aggressive approaches to improve performance and yield. The objective of this review is to overview research findings related to the impact of growth promotant technologies on beef palatability, focusing specifically on the role of implants and ?AA on carcass quality, beef tenderness, and consumer responses for meat palatability. PMID:24158364

Garmyn, A J; Miller, M F

2014-01-01

438

Development of Clinically Relevant Implantable Pressure Sensors: Perspectives and Challenges  

PubMed Central

This review describes different aspects to consider when developing implantable pressure sensor systems. Measurement of pressure is in general highly important in clinical practice and medical research. Due to the small size, light weight and low energy consumption Micro Electro Mechanical Systems (MEMS) technology represents new possibilities for monitoring of physiological parameters inside the human body. Development of clinical relevant sensors requires close collaboration between technological experts and medical clinicians. Site of operation, size restrictions, patient safety, and required measurement range and resolution, are only some conditions that must be taken into account. An implantable device has to operate under very hostile conditions. Long-term in vivo pressure measurements are particularly demanding because the pressure sensitive part of the sensor must be in direct or indirect physical contact with the medium for which we want to detect the pressure. New sensor packaging concepts are demanded and must be developed through combined effort between scientists in MEMS technology, material science, and biology. Before launching a new medical device on the market, clinical studies must be performed. Regulatory documents and international standards set the premises for how such studies shall be conducted and reported. PMID:25248071

Clausen, Ingelin; Glott, Thomas

2014-01-01

439

Development of clinically relevant implantable pressure sensors: perspectives and challenges.  

PubMed

This review describes different aspects to consider when developing implantable pressure sensor systems. Measurement of pressure is in general highly important in clinical practice and medical research. Due to the small size, light weight and low energy consumption Micro Electro Mechanical Systems (MEMS) technology represents new possibilities for monitoring of physiological parameters inside the human body. Development of clinical relevant sensors requires close collaboration between technological experts and medical clinicians.  Site of operation, size restrictions, patient safety, and required measurement range and resolution, are only some conditions that must be taken into account. An implantable device has to operate under very hostile conditions. Long-term in vivo pressure measurements are particularly demanding because the pressure sensitive part of the sensor must be in direct or indirect physical contact with the medium for which we want to detect the pressure. New sensor packaging concepts are demanded and must be developed through combined effort between scientists in MEMS technology, material science, and biology. Before launching a new medical device on the market, clinical studies must be performed. Regulatory documents and international standards set the premises for how such studies shall be conducted and reported. PMID:25248071

Clausen, Ingelin; Glott, Thomas

2014-01-01

440

A mm-sized wirelessly powered and remotely controlled locomotive implantable device  

Microsoft Academic Search

Fully autonomous implantable systems with locomotion can revolutionize medical technology, and include applications ranging from diagnostics to minimally invasive surgery. However, the extreme power requirements of fluid locomotion impose significant design challenges. Using highly efficient and scalable electromagnetic propulsion systems [1], these locomotive devices become possible. Recent work shows that mm-sized antennas in tissue achieve optimal power transfer efficiency in

Anatoly Yakovlev; Daniel Pivonka; Teresa Meng; Ada Poon

2012-01-01

441

Wireless energy delivery and data communication for biomedical sensors and implantable devices  

Microsoft Academic Search

In this paper, we present a wireless power transfer and communication method for biomedical sensors and implants by taking advantage of recently developed witricity technology. New witricity resonator and system designs are described and evaluated by performing both in vitro and in vivo experiments. When compared to the current designs, these new witricity designs demonstrate much improved performances for wireless

Fei Zhang; Xiaoyu Liu; Steven A. Hackworth; Robert J. Sclabassi; Mingui Sun

2009-01-01

442

Optimal design of energy transmission system for implantable device base on WiTricity  

Microsoft Academic Search

WiTricity is a new technology which energy can be transmitted via resonant coupling in the non-radiation near-field. In this paper, optimal design of energy transmission system for implantable devices base on WiTricity is performanced, the influence of system structure parameter on energy transmission efficiency based on WiTricity is investigated.

Qingxin Yang; Guizhi Xu; Jianqiang Jin; Duyan Geng; Weinong Fu; Weili Yan; Mingui Sun

2010-01-01

443

Special features of production of porous implants by diffusion welding and thermal hydrogen treatment  

Microsoft Academic Search

Technology of obtaining porous titanium implants of vertebrae and intervertebral discs by diffusion welding is developed. It is established that additional thermohydrogenous treatment allows for increasing welded strength of the construction and lowering welding heat. Means to improve curability of the porous titanium constructions by thermohydrogenous treatment are shown.

D. E. Gusev; K. S. Senkevich; S. D. Shlyapin; M. Yu. Kollerov

2011-01-01

444

Impurity-profile-based threshold-voltage model of pocket-implanted MOSFETs for circuit simulation  

Microsoft Academic Search

A new threshold voltage (Vth) model has been developed for the pocket-implant technology. The model extracts the threshold condition from the entire mobile charge concentration in the channel with only five additional parameters; the maximum doping concentration (Nsubp) of the pocket profile, the penetration length (Lp) into the channel, and three enhanced short-channel parameters. The model reproduces the measured Vth

Hioraki Ueno; Daisuke Kitamaru; Keiichi Morikawa; Masayasu Tanaka; Mitiko Miura-Mattausch; Hans Juergen Mattausch; Shigetaka Kumashiro; Tetsuya Yamaguchi; Kyoji Yamashita; Noriaki Nakayama

2002-01-01

445

Preparation and Perceptions of Speech-Language Pathologists Working with Children with Cochlear Implants  

ERIC Educational Resources Information Center

This study examined the level of preparedness of North Carolina speech-language pathologists (SLPs) who serve school-aged children with cochlear implants (CIs). A survey distributed to 190 school-based SLPs in North Carolina revealed that 79% of the participants felt they had little to no confidence in managing CI technology or in providing…

Compton, Mary V.; Tucker, Denise A.; Flynn, Perry F.

2009-01-01

446

UWB Characteristics of RF Propagation for Body Mounted and Implanted Sensors Submitted to the Faculty  

E-print Network

the human body to another sensor on the body surface or external. From the image data provided1 UWB Characteristics of RF Propagation for Body Mounted and Implanted Sensors by Jin Chen A Thesis of Department #12;2 Abstract Body Area Network (BAN) technology is related to many applications inside

Pahlavan, Kaveh

447

Remote powering systems of medical implants for maintenance free healthcare applications  

Microsoft Academic Search

For favorable health care sensor devices especially long term monitoring sensors have to be completely imperceptible and maintenance free. A solution on these requirements is an implantable sensor system. The permittivity of body tissue and the desired distance to a remote station confronts the technology with several challenges. To avoid compromises and to be able to optimize both, communication and

Jasmin Walk; Thomas Ussmueller; Robert Weigel; Georg Fischer

2011-01-01

448

EXPERIMENTAL APPLICATION OF VISIBLE ELASTOMER IMPLANTS FOR TAGGING OF PUMPKINSEEDS (Lepomis gibbosus L.)  

Microsoft Academic Search

Experimental laboratory tagging of 120 pumpkinseed sunfish, Lepomis gibbosus L. with subcutaneous injection of a fluorescent elastomer was done. Visible Implant Elastomers (VIE, Northwest Marine Technology, Shaw Island Washington, WA, USA) was used. Tag position was under anterior part of the dorsal fin. Three colours fluorescent elastomers were investigated: yellow, red and orange. Pumpkinseeds mortality rate, length and weight growth

Slavi H. Studenkov; Martina B. Georgieva; Eliza P. Uzunov; Milena N. Nikolova; Boris Velkov

449

Bilateral supraclavicular swelling: an unusual presentation of ruptured Poly Implant Prosthese (PIP) breast implants.  

PubMed

Breast implants manufactured by the French company Poly Implant Prosthese (PIP) have gained notoriety in the International media since the realisation that industrial grade silicone was used in their manufacture with consequent increased risk of implant rupture. At present, it is estimated that there are estimated to be over 40,000 women in the UK with PIP implants. We report an unusual presentation of PIP breast implant rupture as swelling in the supraclavicular fossae. This has not previously been reported in the literature. PMID:22836112

Manickavasagar, Tharjan; Morritt, Andrew N; Offer, Graham J

2013-02-01

450

Efficient Production of Polymyxin in the Surrogate Host Bacillus subtilis by Introducing a Foreign ectB Gene and Disrupting the abrB Gene  

PubMed Central

In our previous study, Bacillus subtilis strain BSK3S, containing a polymyxin biosynthetic gene cluster from Paenibacillus polymyxa, could produce polymyxin only in the presence of exogenously added l-2,4-diaminobutyric acid (Dab). The dependence of polymyxin production on exogenous Dab was removed by introducing an ectB gene encoding the diaminobutyrate synthase of P. polymyxa into BSK3S (resulting in strain BSK4). We found, by observing the complete inhibition of polymyxin synthesis when the spo0A gene was knocked out (strain BSK4-0A), that Spo0A is indispensable for the production of polymyxin. Interestingly, the abrB-spo0A double-knockout mutant, BSK4-0A-rB, and the single abrB mutant, BSK4-rB, showed 1.7- and 2.3-fold increases, respectively, in polymyxin production over that of BSK4. These results coincided with the transcription levels of pmxA in the strains observed by quantitative real-time PCR (qRT-PCR). The AbrB protein was shown to bind directly to the upstream region of pmxA, indicating that AbrB directly inhibits the transcription of polymyxin biosynthetic genes. The BSK4-rB strain, producing high levels of polymyxin, will be useful for the development and production of novel polymyxin derivatives. PMID:22467510

Park, Soo-Young; Choi, Soo-Keun; Kim, Jihoon; Oh, Tae-Kwang

2012-01-01

451

21 CFR 886.3300 - Absorbable implant (scleral buckling method).  

Code of Federal Regulations, 2010 CFR

...scleral buckling method). (a) Identification. An absorbable implant (scleral buckling method) is a device intended to be implanted on the sclera to aid retinal reattachment. (b) Classification. Class...

2010-04-01

452

Improving Sustainability of Ion Implant Modules  

NASA Astrophysics Data System (ADS)

Semiconductor fabs have long been pressured to manage capital costs, reduce energy consumption and increasingly improve efforts to recycle and recover resources. Ion implant tools have been high-profile offenders on all three fronts. They draw such large volumes of air for heat dissipation and risk reduction that historically, they are the largest consumer of cleanroom air of any process tool—and develop energy usage and resource profiles to match. This paper presents a documented approach to reduce their energy consumption and dramatically downsize on-site facilities support for cleanroom air manufacture and abatement. The combination produces significant capital expenditure savings. The case entails applying SAGS Type 1 (sub-atmospheric gas systems) toxic gas packaging to enable engineering adaptations that deliver the energy savings and cost benefits without any reduction in environmental health and safety. The paper also summarizes benefits as they relate to reducing a fabs carbon emission footprint (and longer range advantages relative to potential cap and trade programs) with existing technology.

Mayer, Jim

2011-01-01

453

Preliminary evaluation of implantable MOSFET radiation dosimeters  

NASA Astrophysics Data System (ADS)

In this paper, we report on measurements performed on a new prototype implantable radiation detector that uses metal-oxide semiconductor field effect transistors (MOSFETs) designed for in vivo dosimetry. The dosimeters, which are encapsulated in hermetically sealed glass cylinders, are used in an unbiased mode during irradiation, unlike other MOSFET detectors previously used in radiotherapy applications. They are powered by radio frequency telemetry for dose measurements, obviating the need for a power supply within each capsule. We have studied the dosimetric characteristics of these MOSFET detectors in vitro under irradiation from a 60Co source. The detectors show a dose reproducibility generally within 5% or better, with the main sources of error being temperature fluctuations occurring between the pre- and post-irradiation measurements as well as detector orientation. A better temperature-controlled environment leads to a reproducibility within 2%. Our preliminary in vitro results show clearly that true non-invasive in vivo dosimetry measurements are feasible and can be performed remotely using telemetric technology.

Beddar, A. S.; Salehpour, M.; Briere, T. M.; Hamidian, H.; Gillin, M. T.

2005-01-01

454

Preliminary evaluation of implantable MOSFET radiation dosimeters.  

PubMed

In this paper, we report on measurements performed on a new prototype implantable radiation detector that uses metal-oxide semiconductor field effect transistors (MOSFETs) designed for in vivo dosimetry. The dosimeters, which are encapsulated in hermetically sealed glass cylinders, are used in an unbiased mode during irradiation, unlike other MOSFET detectors previously used in radiotherapy applications. They are powered by radio frequency telemetry fo