Sample records for technology ect implant

  1. Emerging Communication Technologies (ECT) Phase 4 Report

    NASA Technical Reports Server (NTRS)

    Bastin, Gary L.; Harris, William G.; Marin, Jose A.; Nelson, Richard A.

    2005-01-01

    The Emerging Communication Technology (ECT) project investigated three First Mile communication technologies in support of NASA s Crew Exploration Vehicle (CEV), Advanced Range Technology Working Group (ARTWG), and the Advanced Spaceport Technology Working Group (ASTWG). These First Mile technologies have the purpose of interconnecting mobile users with existing Range Communication infrastructures on a 24/7 basis. ECT is a continuation of the Range Information System Management (RISM) task started in 2002. This is the fourth year of the project.

  2. Advances in lens implant technology

    PubMed Central

    Kampik, Anselm; Dexl, Alois K.; Zimmermann, Nicole; Glasser, Adrian; Baumeister, Martin; Kohnen, Thomas

    2013-01-01

    Cataract surgery is one of the oldest and the most frequent outpatient clinic operations in medicine performed worldwide. The clouded human crystalline lens is replaced by an artificial intraocular lens implanted into the capsular bag. During the last six decades, cataract surgery has undergone rapid development from a traumatic, manual surgical procedure with implantation of a simple lens to a minimally invasive intervention increasingly assisted by high technology and a broad variety of implants customized for each patient’s individual requirements. This review discusses the major advances in this field and focuses on the main challenge remaining – the treatment of presbyopia. The demand for correction of presbyopia is increasing, reflecting the global growth of the ageing population. Pearls and pitfalls of currently applied methods to correct presbyopia and different approaches under investigation, both in lens implant technology and in surgical technology, are discussed. PMID:23413369

  3. Microsystems Technology for Retinal Implants

    NASA Astrophysics Data System (ADS)

    Weiland, James

    2005-03-01

    The retinal prosthesis is targeted to treat age-related macular degeneration, retinitis pigmentosa, and other outer retinal degenerations. Simulations of artificial vision have predicted that 600-1000 individual pixels will be needed if a retinal prosthesis is to restore function such as reading large print and face recognition. An implantable device with this many electrode contacts will require microsystems technology as part of its design. An implantable retinal prosthesis will consist of several subsystems including an electrode array and hermetic packaging. Microsystems and microtechnology approaches are being investigated as possible solutions for these design problems. Flexible polydimethylsiloxane (PDMS) substrate electrode arrays and silicon micromachined electrode arrays are under development. Inactive PDMS electrodes have been implanted in 3 dogs to assess mechanical biocompatibility. 3 dogs were followed for 6 months. The implanted was securely fastened to the retina with a single retinal tack. No post-operative complications were evident. The array remained within 100 microns of the retinal surface. Histological evaluation showed a well preserved retina underneath the electrode array. A silicon device with electrodes suspended on micromachined springs has been implanted in 4 dogs (2 acute implants, 2 chronic implants). The device, though large, could be inserted into the eye and positioned on the retina. Histological analysis of the retina from the spring electrode implants showed that spring mounted posts penetrated the retina, thus the device will be redesigned to reduce the strength of the springs. These initial implants will provide information for the designers to make the next generation silicon device. We conclude that microsystems technology has the potential to make possible a retinal prosthesis with 1000 individual contacts in close proximity to the retina.

  4. Microsystem technologies for ophtalmological implants

    NASA Astrophysics Data System (ADS)

    Mokwa, Wilfried

    2003-01-01

    Due to the low power consumption CMOS electronics is ideal for the use in implanted systems. This paper presents two projects working on ophthalmological implants. Both systems are powered by an external RF-field. One system has been developed to measure the intraocular pressure continuously which is important for the therapy of glaucoma patients. The system consists of a micro coil and an integrated pressure transponder chip built into an artificial soft lens. A second example is a very complex system for epiretinal stimulation of the nerve cells of the retina. With such a system it might be possible to give blind people that are suffering from retinitis pigmentosa some visual contact to their surrounding.

  5. TOPICAL REVIEW: Microsystem technologies for implantable applications

    NASA Astrophysics Data System (ADS)

    Receveur, Rogier A. M.; Lindemans, Fred W.; de Rooij, Nicolaas F.

    2007-05-01

    Microsystem technologies (MST) have become the basis of a large industry. The advantages of MST compared to other technologies provide opportunities for application in implantable biomedical devices. This paper presents a general and broad literature review of MST for implantable applications focused on the technical domain. A classification scheme is introduced to order the examples, basic technological building blocks relevant for implantable applications are described and finally a case study on the role of microsystems for one clinical condition is presented. We observe that the microfabricated parts span a wide range for implantable applications in various clinical areas. There are 94 active and 67 commercial 'end items' out of a total of 142. End item refers to the total concept, of which the microsystem may only be a part. From the 105 active end items 18 (13% of total number of end items) are classified as products. From these 18 products, there are only two for chronic use. The number of active end items in clinical, animal and proto phase for chronic use is 17, 13 and 20, respectively. The average year of first publication of chronic end items that are still in the animal or clinical phase is 1994 (n = 7) and 1993 (n = 11), respectively. The major technology market combinations are sensors for cardiovascular, drug delivery for drug delivery and electrodes for neurology and ophthalmology. Together these form 51% of all end items. Pressure sensors form the majority of sensors and there is just one product (considered to be an implantable microsystem) in the neurological area. Micro-machined ceramic packages, glass sealed packages and polymer encapsulations are used. Glass to metal seals are used for feedthroughs. Interconnection techniques such as flip chip, wirebonding or conductive epoxy as used in the semiconductor packaging and assembly industry are also used for manufacturing of implantable devices. Coatings are polymers or metal. As an alternative to implantable primary batteries, rechargeable batteries were introduced or concepts in which energy is provided from the outside based on inductive coupling. Long-term developments aiming at autonomous power are, for example, based on electrostatic conversion of mechanical vibrations. Communication with the implantable device is usually done using an inductive link. A large range of materials commonly used in microfabrication are also used for implantable microsystems.

  6. Implanted : technology and connection in the deaf world

    E-print Network

    Calamia, Joseph Benjamin

    2010-01-01

    In 1984, the FDA approved a medical device called a cochlear implant for adult use in the United States. Unlike assistive hearing technologies that came before it, such as hearing aids, cochlear implants could offer wider ...

  7. Implantable micropump technologies for murine intracochlear infusions.

    PubMed

    Johnson, D G; Waldron, M J; Frisina, R D; Borkholder, D A

    2010-01-01

    Due to the very small size of the mouse inner ear, 600 nL volume, developing effective, controlled infusion systems is quite challenging. Key technologies have been created to minimize both size and power for an implantable pump for murine intracochlear infusions. A method for coupling fine capillary tubing to microfluidic channels is presented which provides low volume, biocompatible interconnects withstanding pressures as high as 827 kPa (120 psi) and consuming less than 20 nL of volume exiting in-plane with the pump. Surface micromachined resistive bridges integrated into the flow channel for anemometry based flow rate measurement have been optimized for low power operation in the ultra-low flow rate regime. A process for creation of deformable diaphragms over pump chambers with simultaneous coating of the microfluidic channels has been developed allowing integration of a biocompatible fluid flow path. These advances represent enabling capabilities for a drug delivery system suitable for space constrained applications such as subcutaneous implantation in mice. PMID:21096713

  8. Evaluating the Feasibility of Using Remote Technology for Cochlear Implants

    ERIC Educational Resources Information Center

    Goehring, Jenny L.; Hughes, Michelle L.; Baudhuin, Jacquelyn L.

    2012-01-01

    The use of remote technology to provide cochlear implant services has gained popularity in recent years. This article contains a review of research evaluating the feasibility of remote service delivery for recipients of cochlear implants. To date, published studies have determined that speech-processor programming levels and other objective tests…

  9. Ion sources for ion implantation technology (invited)

    SciTech Connect

    Sakai, Shigeki, E-mail: sakai-shigeki@nissin.co.jp; Hamamoto, Nariaki; Inouchi, Yutaka; Umisedo, Sei; Miyamoto, Naoki [Nissin Ion Equipment co., ltd, 575 Kuze-Tonoshiro-cho Minami-ku, Kyoto 601-8205 (Japan)] [Nissin Ion Equipment co., ltd, 575 Kuze-Tonoshiro-cho Minami-ku, Kyoto 601-8205 (Japan)

    2014-02-15

    Ion sources for ion implantation are introduced. The technique is applied not only to large scale integration (LSI) devices but also to flat panel display. For LSI fabrication, ion source scheduled maintenance cycle is most important. For CMOS image sensor devices, metal contamination at implanted wafer is most important. On the other hand, to fabricate miniaturized devices, cluster ion implantation has been proposed to make shallow PN junction. While for power devices such as silicon carbide, aluminum ion is required. For doping processes of LCD fabrication, a large ion source is required. The extraction area is about 150 cm × 10 cm, and the beam uniformity is important as well as the total target beam current.

  10. Ion sources for ion implantation technology (invited)

    NASA Astrophysics Data System (ADS)

    Sakai, Shigeki; Hamamoto, Nariaki; Inouchi, Yutaka; Umisedo, Sei; Miyamoto, Naoki

    2014-02-01

    Ion sources for ion implantation are introduced. The technique is applied not only to large scale integration (LSI) devices but also to flat panel display. For LSI fabrication, ion source scheduled maintenance cycle is most important. For CMOS image sensor devices, metal contamination at implanted wafer is most important. On the other hand, to fabricate miniaturized devices, cluster ion implantation has been proposed to make shallow PN junction. While for power devices such as silicon carbide, aluminum ion is required. For doping processes of LCD fabrication, a large ion source is required. The extraction area is about 150 cm × 10 cm, and the beam uniformity is important as well as the total target beam current.

  11. Amplification, Technology, and Cochlear Implants for Infants.

    ERIC Educational Resources Information Center

    Adam, Arlie J.

    1993-01-01

    Early amplification is crucial to efficient habilitation and development of oral communication skills in hearing-impaired infants. Initial evaluation and fitting of amplification is a joint effort by the audiologist, therapist, and parents, whether the child uses traditional hearing aids or cochlear implants, and should be supplemented by a…

  12. Biofilm Disrupting Technology for Orthopedic Implants: What's on the Horizon?

    PubMed

    Connaughton, Alexander; Childs, Abby; Dylewski, Stefan; Sabesan, Vani J

    2014-01-01

    The use of orthopedic implants in joints has revolutionized the treatment of patients with many debilitating chronic musculoskeletal diseases such as osteoarthritis. However, the introduction of foreign material into the human body predisposes the body to infection. The treatment of these infections has become very complicated since the orthopedic implants serve as a surface for multiple species of bacteria to grow at a time into a resistant biofilm layer. This biofilm layer serves as a protectant for the bacterial colonies on the implant making them more resistant and difficult to eradicate when using standard antibiotic treatment. In some cases, the use of antibiotics alone has even made the bacteria more resistant to treatment. Thus, there has been surge in the creation of non-antibiotic anti-biofilm agents to help disrupt the biofilms on the orthopedic implants to help eliminate the infections. In this study, we discuss infections of orthopedic implants in the shoulder then we review the main categories of anti-biofilm agents that have been used for the treatment of infections on orthopedic implants. Then, we introduce some of the newer biofilm disrupting technology that has been studied in the past few years that may advance the treatment options for orthopedic implants in the future. PMID:25705632

  13. Evaluating the Feasibility of Using Remote Technology for Cochlear Implants

    PubMed Central

    Goehring, Jenny L.; Hughes, Michelle L.; Baudhuin, Jacquelyn L.

    2012-01-01

    The use of remote technology to provide cochlear implant services has gained popularity in recent years. This article contains a review of research evaluating the feasibility of remote service delivery for recipients of cochlear implants. To date, published studies have determined that speech-processor programming levels and other objective tests (electrode impedance and electrically evoked compound action potentials) are equivalent to those obtained in the face-to-face condition. Despite these promising findings, speech perception using remote technology has proven to be more challenging. Previous investigations have evaluated speech perception with recipients of cochlear implants using videoconference (Polycom) equipment in nonsound-treated rooms (due to lack of access to audiological sound booths in rural areas). Results have revealed poorer speech perception scores using remote technology compared to face-to-face results. Additionally, it has been shown that Polycom transmission of a speech stimulus does not cause significant compression for adequate evaluation; rather, poorer results are due to testing performed in nonsound-treated environments. Based on the literature, telepractice is a feasible option for cochlear implant service delivery. Barriers to the wide-spread use of remote services for recipients of cochlear implants include a uniform system for the evaluation of speech perception, validation of services for pediatric recipients and initial activations, license reciprocity, and reimbursement for services. PMID:25221361

  14. IMAGE: A new type of implantable device uses flexible silicon technology.

    E-print Network

    Rogers, John A.

    IMAGE: A new type of implantable device uses flexible silicon technology. Click here for more generation of active, flexible, implantable devices for applications in many areas of the body," says co arrhythmias. "Implantable silicon-based devices have the potential to serve as tools for mapping and treating

  15. Evolution of Ion Implantation Technology and its Contribution to Semiconductor Industry

    SciTech Connect

    Tsukamoto, Katsuhiro [Mitsubishi Electric Corporation (Japan); Kuroi, Takashi; Kawasaki, Yoji [Renesas Electronics Corporation (Japan)

    2011-01-07

    Industrial aspects of the evolution of ion implantation technology will be reviewed, and their impact on the semiconductor industry will be discussed. The main topics will be the technology's application to the most advanced, ultra scaled CMOS, and to power devices, as well as productivity improvements in implantation technology. Technological insights into future developments in ion-related technologies for emerging industries will also be presented.

  16. Plasma-based ion implantation and deposition: a review of physics, technology, and applications

    Microsoft Academic Search

    Jacques Pelletier; Andre Anders

    2005-01-01

    After pioneering work in the 1980s, plasma-based ion implantation (PBII) and plasma-based ion implantation and deposition (PBIID) can now be considered mature technologies for surface modification and thin film deposition. This review starts by looking at the historical development and recalling the basic ideas of PBII. Advantages and disadvantages are compared to conventional ion beam implantation and physical vapor deposition

  17. Implants

    MedlinePLUS

    ... They are used to support crowns , bridges or dentures . Implants are surgically placed in your jawbone. Most ... other methods of replacing missing teeth, such as dentures. There are many reasons it's important to replace ...

  18. Manufacturing technology program to develop a production ion implantation facility for processing bearings and tools

    Microsoft Academic Search

    F. A. Smidt; B. D. Sartwell

    1985-01-01

    A manufacturing technology project to expedite the development and transfer of ion implantation of metals to industrial practice is described. The objective of this project is to develop a prototype production facility to implant several types of aircraft and instrument bearings, and stamping and forming tools to increase their resistance to corrosion and wear and, therefore, increase their lifetime. Research

  19. [Optimization of elastic intraocular lens implantation technology in the phacoemulsification of different types of cataract].

    PubMed

    Khafizova, G F; Verigo, E N

    2007-01-01

    The functional and clinical results of implantation of various models of intraocular lenses (IOL) were assessed, by taking into account its procedure (applying a forceps or an injector). The optimum technology for implanting elastic IOLs was proposed, depending on the etiology of cataract. Analysis of surgical outcomes in 172 patients (207 eyes) revealed the characteristic complications, the specificity of implantation of various models of elastic IOLs, the advantages and disadvantages of the forceps- and injector-based implantations in age-related cataract, in patients with complicated cataracts in the presence of glaucoma, myopia, diabetes, and moderate- and high-degree hyperopia. PMID:18225521

  20. Nanomaterials and synergistic low intensity direct current (LIDC) stimulation technology for orthopaedic implantable medical devices

    PubMed Central

    Samberg, Meghan E.; Cohen, Paul H.; Wysk, Richard A.; Monteiro-Riviere, Nancy A.

    2012-01-01

    Nanomaterials play a significant role in biomedical research and applications due to their unique biological, mechanical, and electrical properties. In recent years, they have been utilised to improve the functionality and reliability of a wide range of implantable medical devices ranging from well-established orthopaedic residual hardware devices (e.g. hip implants) that can repair defects in skeletal systems to emerging tissue engineering scaffolds that can repair or replace organ functions. This review summarizes the applications and efficacies of these nanomaterials that include synthetic or naturally occurring metals, polymers, ceramics, and composites in orthopaedic implants, the largest market segment of implantable medical devices. The importance of synergistic engineering techniques that can augment or enhance the performance of nanomaterial applications in orthopaedic implants is also discussed,, the focus being on a low intensity direct electric current (LIDC) stimulation technology to promote the long-term antibacterial efficacy of oligodynamic metal-based surfaces by ionization, while potentially accelerating tissue growth and osseointegration. While many nanomaterials have clearly demonstrated their ability to provide more effective implantable medical surfaces, further decisive investigations are necessary before they can translate into medically safe and commercially viable clinical applications. The paper concludes with a discussion about some of the critical impending issues with the application of nanomaterials-based technologies in implantable medical devices, and potential directions to address these. PMID:23335493

  1. Evolution and acceptability of medical applications of RFID implants among early users of technology.

    PubMed

    Smith, Alan D

    2007-01-01

    RFID as a wireless identification technology that may be combined with microchip implants have tremendous potential in today's market. Although these implants have their advantages and disadvantages, recent improvements how allowed for implants designed for humans. Focus was given to the use of RFID tags and its effects on technology and CRM through a case study on VeriChip, the only corporation to hold the rights and the patent to the implantable chip for humans, and an empirically based study on working professionals to measure perceptions by early adopters of such technology. Through hypotheses-testing procedures, it was found that although some resistance to accept microchip implants was found in several applications, especially among gender, it was totally expected that healthcare and medical record keeping activities would be universally treated in a positive light and the use of authorities (namely governmental agencies) would be equally treated in a negative light by both sexes. Future trends and recommendations are presented along with statistical results collected through personal interviews. PMID:19042524

  2. Contacting the brain--aspects of a technology assessment of neural implants.

    PubMed

    Decker, Michael; Fleischer, Torsten

    2008-12-01

    The public interest in neural implants has grown considerably in recent years. Progress within related research areas in combination with increasing--albeit overly optimistic and indiscriminate--mass media coverage have led to the impression that the possibilities of neural prosthetics have grown enormously. But a closer look reveals that the reasons for the intensified interest are varied and cannot be attributed to technical progress alone. Some neural prostheses that have been under development for many years have not left the clinical development phase despite intensive research activities. Other implants, like cardiac pacemakers and cochlea implants, are mature products that have already been implanted in a large number of patients. From the public perspective and in media reports, progress in the development of neural implants is associated with new achievements in other fields of neuroscience. Communications on new applications of functional magnetic resonance imaging (fMRI) may suggest that a number of cognitive functions are now easily accessible with technological means. The fact that the interpretation of the results of fMRI studies depends on many conditions and is partly disputed also within the scientific community has been discussed in many publications but only very limited, in the general media. Besides this, research results and implementations in the area of electroencephalography and magnetoencephalography have sparked further debate on the question of free will, on determinism and indeterminism, and have attracted a large media response. The purpose of this paper is to discuss some societal and ethical aspects of neural implants from a technology assessment perspective. Technology assessment (TA) aims at providing knowledge about impacts and consequences of (new) technologies as well as about political and societal ways of dealing with them. It reflects about implementation conditions of technology and potential technology conflicts. Over the last years, neural implants became a subject for TA since they have gained a higher attention in both the political arena and the general public. Especially the ethical and social implications of technologies that electrically stimulate the brain and the possibilities of changing personality traits, changing moods, and perhaps enhancing human cognitive capabilities are central issues in related discussions. In this paper, we want to briefly summarize some of the key arguments as well as topics for future discussion and research. PMID:19072906

  3. Implantable sensor technology: measuring bone and joint biomechanics of daily life in vivo

    PubMed Central

    2013-01-01

    Stresses and strains are major factors influencing growth, remodeling and repair of musculoskeletal tissues. Therefore, knowledge of forces and deformation within bones and joints is critical to gain insight into the complex behavior of these tissues during development, aging, and response to injury and disease. Sensors have been used in vivo to measure strains in bone, intraarticular cartilage contact pressures, and forces in the spine, shoulder, hip, and knee. Implantable sensors have a high impact on several clinical applications, including fracture fixation, spine fixation, and joint arthroplasty. This review summarizes the developments in strain-measurement-based implantable sensor technology for musculoskeletal research. PMID:23369655

  4. Full chip implant correction with wafer topography OPC modeling in 2x nm bulk technologies

    NASA Astrophysics Data System (ADS)

    Michel, J.-C.; Le Denmat, J.-C.; Sungauer, E.; Robert, F.; Yesilada, E.; Armeanu, A.-M.; Entradas, J.; Sturtevant, J. L.; Do, T.; Granik, Y.

    2013-09-01

    Ionic implantation photolithography step considered to be non critical started to be influenced by unwanted overexposure by wafer topography with technology node downscaling evolution [1], [2]. Starting from 2xnm technology nodes, implant patterns modulated on wafer by classical implant proximity effects are also influenced by wafer topography which can cause drastic pattern degradation [2], [3]. This phenomenon is expected to be attenuated by the use of anti-reflecting coating but it increases process complexity and involves cost and cycle time penalty. As a consequence, computational lithography solutions are currently under development in order to correct wafer topographical effects on mask [3]. For ionic implantation source Drain (SD) on Silicon bulk substrate, wafer topography effects are the consequence of active silicon substrate, poly patterns, STI stack, and transitions between patterned wafer stack. In this paper, wafer topography aware OPC modeling flow taking into account stack effects for bulk technology is presented. Quality check of this full chip stack aware OPC model is shown through comparison of mask computational verification and known systematic defectivity on wafer. Also, the integration of topographical OPC model into OPC flow for chip scale mask correction is presented with quality and run time penalty analysis.

  5. Cryogenic ion implantation near amorphization threshold dose for halo/extension junction improvement in sub-30 nm device technologies

    SciTech Connect

    Park, Hugh; Todorov, Stan; Colombeau, Benjamin; Rodier, Dennis; Kouzminov, Dimitry; Zou Wei; Guo Baonian; Khasgiwale, Niranjan; Decker-Lucke, Kurt [Applied Materials, Varian Semiconductor Equipment, 35 Dory Road, Gloucester, Massachusetts 01930 (United States)

    2012-11-06

    We report on junction advantages of cryogenic ion implantation with medium current implanters. We propose a methodical approach on maximizing cryogenic effects on junction characteristics near the amorphization threshold doses that are typically used for halo implants for sub-30 nm technologies. BF{sub 2}{sup +} implant at a dose of 8 Multiplication-Sign 10{sup 13}cm{sup -2} does not amorphize silicon at room temperature. When implanted at -100 Degree-Sign C, it forms a 30 - 35 nm thick amorphous layer. The cryogenic BF{sub 2}{sup +} implant significantly reduces the depth of the boron distribution, both as-implanted and after anneals, which improves short channel rolloff characteristics. It also creates a shallower n{sup +}-p junction by steepening profiles of arsenic that is subsequently implanted in the surface region. We demonstrate effects of implant sequences, germanium preamorphization, indium and carbon co-implants for extension/halo process integration. When applied to sequences such as Ge+As+C+In+BF{sub 2}{sup +}, the cryogenic implants at -100 Degree-Sign C enable removal of Ge preamorphization, and form more active n{sup +}-p junctions and steeper B and In halo profiles than sequences at room temperature.

  6. Design of Mixed-Signal Circuits for Wireless Communication Systems and Implanted Neural Devices in 3D Technology

    E-print Network

    Stanacevic, Milutin

    Design of Mixed-Signal Circuits for Wireless Communication Systems and Implanted Neural Devices modulator is designed and the design methodology is developed. Implantable neural prosthesis and brain, circuit design in the 3D technology has not been fully understood. The design methodology should also

  7. Introduction to Special Issue on Implantable Electronics With great advances in electronics and electrode technologies, it has become possible

    E-print Network

    Bhunia, Swarup

    peer review process. These articles focus on a wide range of design and computing aspects related and electrode technologies, it has become possible to realize implantable biomedical microsystems that interface. Today, miniaturized wireless implantable systems are changing the face of biomedical research

  8. Wafer topography modeling for ionic implantation mask correction dedicated to 2x nm FDSOI technologies

    NASA Astrophysics Data System (ADS)

    Michel, Jean-Christophe; Le Denmat, Jean-Christophe; Sungauer, Elodie; Robert, Frédéric; Yesilada, Emek; Armeanu, Ana-Maria; Entradas, Jorge; Sturtevant, John L.; Do, Thuy; Granik, Yuri

    2013-04-01

    Reflection by wafer topography and underlying layers during optical lithography can cause unwanted exposure in the resist [1]. This wafer stack effect phenomenon which is neglected for larger nodes than 45nm, is becoming problematic for 32nm technology node and below at the ionic implantation process. This phenomenon is expected to be attenuated by the use of anti-reflecting coating but increases process complexity and adds cost and cycle time penalty. As a consequence, an OPC based solution is today under evaluation to cope with stack effects involved in ionic implantation patterning [2] [3]. For the source drain (SD) ionic implantation process step on 28nm Fully Depleted Silicon-on-Insulator (FDSOI) technology, active silicon areas, poly silicon patterns, Shallow Trench Isolation (STI), Silicon-on-Insulator (SOI) areas and the transitions between these different regions result in significant SD implant pattern critical dimension variations. The large number of stack variations involved in these effects implies a complex modeling to simulate pattern degradations. This paper deals with the characterization of stack effects on 28nm node using SOI substrates. The large number of measurements allows to highlight all individual and combined stack effects. A new modeling flow has been developed in order to generate wafer stack aware OPC model. The accuracy and the prediction of the model is presented in this paper.

  9. The combination methodic of diffusion and implantation technologies for creating optic wave-guided layers in lithium niobate

    NASA Astrophysics Data System (ADS)

    Orlikov, L. N.; Orlikov, N. L.; Arestov, S. I.; Mambetova, K. M.; Shandarov, S. M.

    2015-04-01

    The implantation of copper into Lithium Niobate in the prohibited crystal zone forms a definite energetic level for optic transits. This paper examines conditions of optic wave-guided layers formation on Niobate Lithium due to the method of implantation copper ions with the next diffusion. Reflect Spectrum in consequences implantation is extended. The transfer of the optical power from the primary beam into the another beam was discovered and in reverse. Photo galvanic characteristics of implantation specimen identity of crystal by traditional technology and doping CuO manufacture.

  10. History of some early developments in ion-implantation technology leading to silicon transistor manufacturing

    Microsoft Academic Search

    RICHARD B. FAIR

    1998-01-01

    Ion implantation of dopant impurities to form p-n junctions and other doped regions in silicon transistors has evolved from an experimental curiosity in solid-state physics to become a dominant technology in today's integrated circuit manufacturing. This paper traces the key inventions and early developments in ion beam doping concepts from the early 1950's through the 1970's as they were applied

  11. The impact of public opinion on medical technology: the case of artificial heart implants.

    PubMed

    Roeder, P W; Whitler, E T

    1986-01-01

    A public opinion survey was conducted in the spring of 1985 in Kentucky to assess public attitudes toward artificial heart technology. The data, based on consumer and citizen perspectives, indicate that the public is interested in and aware of the technology and recent implant surgeries. More knowledgeable respondents are more likely to support Humana's involvement, but less likely to want an artificial heart and other organs to continue life, and less willing to support equitable access and increased taxes to achieve this equity. Technological optimists are more willing to have the heart and other organs as needed and more willing to have their taxes increased to pay for the technology for all in need. Optimists also see nothing wrong with Humana's involvement in this technology. People's judgments on artificial heart technology vary, depending on whether they see it as potentially desirable for themselves as opposed to possible implications for others and the broader society. Although both perspectives are crucial for understanding the role of public opinion on the further development of this technology, it must be recognized that the two perspectives might have different impacts, depending on societal judgment of whether the decision to proceed with further development of the technology is mostly a public or private choice. PMID:10278617

  12. Ion beam technology applications study. [ion impact, implantation, and surface finishing

    NASA Technical Reports Server (NTRS)

    Sellen, J. M., Jr.; Zafran, S.; Komatsu, G. K.

    1978-01-01

    Specific perceptions and possible ion beam technology applications were obtained as a result of a literature search and contact interviews with various institutions and individuals which took place over a 5-month period. The use of broad beam electron bombardment ion sources is assessed for materials deposition, removal, and alteration. Special techniques examined include: (1) cleaning, cutting, and texturing for surface treatment; (2) crosslinking of polymers, stress relief in deposited layers, and the creation of defect states in crystalline material by ion impact; and (3) ion implantation during epitaxial growth and the deposition of neutral materials sputtered by the ion beam. The aspects, advantages, and disadvantages of ion beam technology and the competitive role of alternative technologies are discussed.

  13. A programmed release multi-drug implant fabricated by three-dimensional printing technology for bone tuberculosis therapy

    Microsoft Academic Search

    Weigang Wu; Qixin Zheng; Xiaodong Guo; Jianhua Sun; Yudong Liu

    2009-01-01

    In the world, bone tuberculosis is still very difficult to treat and presents a challenge to clinicians. In this study, we utilized 3D printing technology to fabricate a programmed release multi-drug implant for bone tuberculosis therapy. The construction of the drug implant was a multi-layered concentric cylinder divided into four layers from the center to the periphery. Isoniazid and rifampicin

  14. Repairing an implant titanium milled framework using laser welding technology: a clinical report.

    PubMed

    Prasad, Soni; Monaco, Edward A

    2009-04-01

    The application of laser welding technology allows titanium to be welded predictably and precisely to achieve accurate fit of a milled framework. Laser energy results in localized heat production, thereby reducing thermal expansion. Unlike soldering, laser energy can be directed to a small area, making it possible to laser weld close to acrylic resin or ceramic. This article describes the use of laser welding to repair an implant titanium milled fixed denture. A quick, cost-effective, accurate repair was accomplished, and the repaired framework possessed adequate strength and the same precise fit as the original framework. PMID:19328274

  15. Veranstalltungsform Titel Sprache SWS ECTS Prfung Seminar Aktuelle Probleme der Wirtschafts-und Unternehmensethik Deutsch 3 2-4 Referat (ECTS: 2) zustzlich Hausarbeit (ECTS: 4)

    E-print Network

    Cremers, Daniel

    Unternehmensethik Deutsch 3 2-4 Referat (ECTS: 2) zusätzlich Hausarbeit (ECTS: 4) Seminar Arbeits- und Lebenswelten in der Literatur Deutsch 2 2 bis 3 Referat/Präsentation (2 ECTS), zusätzlich Protokoll, Hausarbeit (3 ECTS) Workshop Decision Making in Complex Systems ­ Part II Deutsch 1 1 Essay and Mini

  16. Technology Advances and Challenges in Hermetic Packaging for Implantable Medical Devices

    Microsoft Academic Search

    Guangqiang Jiang; David D. Zhou

    2010-01-01

    \\u000a Many implantable medical devices contain sophisticated electronic circuits. Hermetic packaging is required to provide the\\u000a implant’s electronic circuitry with protection from the harsh environment of the human body. This chapter provides a review\\u000a of available hermetic sealing methods and their applications. General considerations of implantable medical device packaging\\u000a are discussed. Various testing methods applicable to the packaging of implantable medical

  17. The Cresco Bridge and implant concept: presentation of a technology for fabrication of abutment-free, passively fitting superstructures.

    PubMed

    Helldén, Leif B; Ericson, Gunnel; Olsson, Carl-Olof

    2005-02-01

    This article describes a new and cost-effective concept comprising innovative and simplified clinical and laboratory procedures for the rational fabrication of abutment-free, cast-titanium superstructures with passive fit to implants. Other alloys, such as precious metal or cobalt-chromium, can also be used. The precision of fit between the implants and superstructure is obtained by the Cresco Ti Precision method. This method is a user-friendly technology and can be adapted to most implant systems on the market. The method does not include any abutments, even when implants are positioned in extremely different angulations or inclined in a facial or palatal direction. Coupled with a simple All Parts Included (API) delivery system, the concept therefore represents an efficient treatment alternative. PMID:15736782

  18. Bypassing the learning curve in permanent seed implants using state-of-the-art technology

    SciTech Connect

    Beaulieu, Luc [Departement de Radio-oncologie, Centre Hospitalier Universitaire de Quebec, Hotel-Dieu de Quebec, Quebec, PQ (Canada)]. E-mail: beaulieu@phy.ulaval.ca; Evans, Dee-Ann Radford [Departments of Radiation Oncology and Medical Physics, Tom Baker Cancer Centre, Calgary, AB (Canada); Aubin, Sylviane [Departement de Radio-oncologie, Centre Hospitalier Universitaire de Quebec, Hotel-Dieu de Quebec, Quebec, PQ (Canada); Angyalfi, Steven [Departments of Radiation Oncology and Medical Physics, Tom Baker Cancer Centre, Calgary, AB (Canada); Husain, Siraj [Departments of Radiation Oncology and Medical Physics, Tom Baker Cancer Centre, Calgary, AB (Canada); Kay, Ian [Departments of Radiation Oncology and Medical Physics, Tom Baker Cancer Centre, Calgary, AB (Canada); Martin, Andre-Guy [Departement de Radio-oncologie, Centre Hospitalier Universitaire de Quebec, Hotel-Dieu de Quebec, Quebec, PQ (Canada); Varfalvy, Nicolas [Departement de Radio-oncologie, Centre Hospitalier Universitaire de Quebec, Hotel-Dieu de Quebec, Quebec, PQ (Canada); Vigneault, Eric [Departement de Radio-oncologie, Centre Hospitalier Universitaire de Quebec, Hotel-Dieu de Quebec, Quebec, PQ (Canada); Dunscombe, Peter [Departments of Radiation Oncology and Medical Physics, Tom Baker Cancer Centre, Calgary, AB (Canada)

    2007-01-01

    Purpose: The aim of this study was to demonstrate, based on clinical postplan dose distributions, that technology can be used efficiently to eliminate the learning curve associated with permanent seed implant planning and delivery. Methods and Materials: Dose distributions evaluated 30 days after the implant of the initial 22 consecutive patients treated with permanent seed implants at two institutions were studied. Institution 1 (I1) consisted of a new team, whereas institution 2 (I2) had performed more than 740 preplanned implantations over a 9-year period before the study. Both teams had adopted similar integrated systems based on three-dimensional (3D) transrectal ultrasonography, intraoperative dosimetry, and an automated seed delivery and needle retraction system (FIRST, Nucletron). Procedure time and dose volume histogram parameters such as D90, V100, V150, V200, and others were collected in the operating room and at 30 days postplan. Results: The average target coverage from the intraoperative plan (V100) was 99.4% for I1 and 99.9% for I2. D90, V150, and V200 were 191.4 Gy (196.3 Gy), 75.3% (73.0%), and 37.5% (34.1%) for I1 (I2) respectively. None of these parameters shows a significant difference between institutions. The postplan D90 was 151.2 Gy for I1 and 167.3 Gy for I2, well above the 140 Gy from the Stock et al. analysis, taking into account differences at planning, results in a p value of 0.0676. The procedure time required on average 174.4 min for I1 and 89 min for I2. The time was found to decrease with the increasing number of patients. Conclusion: State-of-the-art technology enables a new brachytherapy team to obtain excellent postplan dose distributions, similar to those achieved by an experienced team with proven long-term clinical results. The cost for bypassing the usual dosimetry learning curve is time, with increasing team experience resulting in shorter treatment times.

  19. Implant ethics

    PubMed Central

    Hansson, S

    2005-01-01

    Implant ethics is defined here as the study of ethical aspects of the lasting introduction of technological devices into the human body. Whereas technological implants relieve us of some of the ethical problems connected with transplantation, other difficulties arise that are in need of careful analysis. A systematic approach to implant ethics is proposed. The major specific problems are identified as those concerning end of life issues (turning off devices), enhancement of human capabilities beyond normal levels, mental changes and personal identity, and cultural effects. PMID:16131553

  20. Ironic Technology: Old Age and the implantable cardioverter defibrillator in US health care

    PubMed Central

    Kaufman, Sharon R.; Mueller, Paul S.; Ottenberg, Abigale L.; Koenig, Barbara A.

    2010-01-01

    We take the example of cardiac devices, specifically the implantable cardioverter defibrillator, or ICD, to explore the complex cultural role of technology in medicine today. We focus on persons age 80 and above, for whom ICD use is growing in the U.S. We highlight an ironic feature of this device. While it postpones death and ‘saves’ life by thwarting a lethal heart rhythm, it also prolongs living in a state of dying from heart failure. In that regard the ICD is simultaneously a technology of life extension and dying. We explore that irony among the oldest age group -- those whose considerations of medical interventions are framed by changing societal assumptions of what constitutes premature death, the appropriate time for death and medicine’s goals in an aging society. Background to the rapidly growing use of this device among the elderly is the ‘technological imperative’ in medicine, bolstered today by the value given to evidence-based studies. We show how evidence contributes to standards of care and to the expansion of Medicare reimbursement criteria. Together, those factors shape the ethical necessity of physicians offering and patients accepting the ICD in late life. Two ethnographic examples document the ways in which those factors are lived in treatment discussions and in expectations about death and longevity. PMID:21126815

  1. Veranstalltungsform Titel Untertitel Sprache SWS ECTS Prfung Seminar Aktuelle Probleme der Wirtschafts-und Unternehmensethik Deutsch 3 2-4 Referat (ECTS: 2) zustzlich Hausarbeit (ECTS: 4)

    E-print Network

    Cengarle, María Victoria

    Wirtschafts- und Unternehmensethik Deutsch 3 2-4 Referat (ECTS: 2) zusätzlich Hausarbeit (ECTS: 4) Seminar Arbeits- und Lebenswelten in der Literatur Deutsch 2 2 bis 3 Referat/Präsentation (2 ECTS), zusätzlich in modelling complex systems ­ Agents in NetworksDeutsch 1 1 Essay and Mini-Simulation Project Seminar Der

  2. Surgical Planning and Prosthesis Construction Using Computed Tomography, CAD\\/CAM Technology, and the Internet for Immediate Loading of Dental Implants

    Microsoft Academic Search

    stephen f. balshi; glenn j. wolfinger; thomas j. balshi

    2006-01-01

    This report describes a protocol that uses computer technology and medical imaging to virtually place anterior and posterior dental implants and to construct a precise surgical template and prosthesis, which is connected at the time of implant placement. This procedure drastically reduces patient office time, surgical treatment time, and the degree of post-treatment recovery. Patients with an edentulous arch or

  3. Plasma-based ion implantation: a valuable technology for the elaboration of innovative materials and nanostructured thin films

    NASA Astrophysics Data System (ADS)

    Vempaire, D.; Pelletier, J.; Lacoste, A.; Béchu, S.; Sirou, J.; Miraglia, S.; Fruchart, D.

    2005-05-01

    Plasma-based ion implantation (PBII), invented in 1987, can now be considered as a mature technology for thin film modification. After a brief recapitulation of the principle and physics of PBII, its advantages and disadvantages, as compared to conventional ion beam implantation, are listed and discussed. The elaboration of thin films and the modification of their functional properties by PBII have already been achieved in many fields, such as microelectronics (plasma doping/PLAD), biomaterials (surgical implants, bio- and blood-compatible materials), plastics (grafting, surface adhesion) and metallurgy (hard coatings, tribology), to name a few. The major advantages of PBII processing lie, on the one hand, in its flexibility in terms of ion implantation energy (from 0 to 100 keV) and operating conditions (plasma density, collisional or non-collisional ion sheath), and, on the other hand, in the easy transferrability of processes from the laboratory to industry. The possibility of modifying the composition and physical nature of the films, or of drastically changing their physical properties over several orders of magnitude makes this technology very attractive for the elaboration of innovative materials, including metastable materials, and the realization of micro- or nanostructures. A review of the state of the art in these domains is presented and illustrated through a few selected examples. The perspectives opened up by PBII processing, as well as its limitations, are discussed.

  4. A longitudinal clinical assessment of spark erosion technology in implant-retained overdenture prostheses: A preliminary report

    Microsoft Academic Search

    Joseph A. Toljanic; Dimitris Antoniou; R. Scott Clark; Louis Graham

    1997-01-01

    Statement of problem. As adapted for the dental profession, spark erosion technology permits precise machining of retentive metal overdenture frameworks for use in implant prosthetics.Purpose. The resultant prostheses are retentive and provide a number of benefits offered by both conventional overdenture and fixed prosthetic designs.Material and methods. Preliminary data collected from an ongoing 5-year clinical trial were reviewed to qualitatively

  5. Rationale for the Use of CAD/CAM Technology in Implant Prosthodontics

    PubMed Central

    Abduo, Jaafar; Lyons, Karl

    2013-01-01

    Despite the predictable longevity of implant prosthesis, there is an ongoing interest to continue to improve implant prosthodontic treatment and outcomes. One of the developments is the application of computer-aided design and computer-aided manufacturing (CAD/CAM) to produce implant abutments and frameworks from metal or ceramic materials. The aim of this narrative review is to critically evaluate the rationale of CAD/CAM utilization for implant prosthodontics. To date, CAD/CAM allows simplified production of precise and durable implant components. The precision of fit has been proven in several laboratory experiments and has been attributed to the design of implants. Milling also facilitates component fabrication from durable and aesthetic materials. With further development, it is expected that the CAD/CAM protocol will be further simplified. Although compelling clinical evidence supporting the superiority of CAD/CAM implant restorations is still lacking, it is envisioned that CAD/CAM may become the main stream for implant component fabrication. PMID:23690778

  6. Delayed Onset and Prolonged ECT-Related Delirium

    PubMed Central

    Pandurangi, Ananda; Levenson, James

    2013-01-01

    Electroconvulsive therapy (ECT) is effective in the treatment of depression. Delayed post-ECT delirium is rare but can occur in a small subset of patients with risk factors and in most cases resolves with the use of psychotropic medications. We report a unique presentation of a patient who developed a delayed post-ECT delirium with fecal incontinence that commenced 24 hours after the administration of ECT. The condition resolved spontaneously after 48 hours without the use of psychotropic medications. PMID:24078892

  7. FIRST SEMESTER (27.5 ECTS) Cultural History of Tourism 3

    E-print Network

    Krause, Rolf

    2 FIRST SEMESTER (27.5 ECTS) Cultural History of Tourism 3 Economics and Politics of International Tourism 4.5 E-tourism Technology Labs 3 International Relations and Tourism 3 New Media for Tourism Communication 4.5 Research Methods in Tourism 3 Rhetoric and Persuasion in Tourism Communication 3 Tourism

  8. Construction of an implant-retained auricular prosthesis with the aid of contemporary digital technologies: a clinical report.

    PubMed

    Hatamleh, Muhanad M; Watson, Jason

    2013-02-01

    Implant-retained auricular prostheses are a successful treatment modality for children with microtia. They involve only minor surgical intervention of implant placement and result in an esthetically pleasing outcome. Integration of digital technologies (DT) in the prosthetic reconstruction process is a new approach toward enhancing outcomes. In this report we present a case of auricular prosthetic reconstruction following two implant placements in the right mastoid region. The ear prosthesis was constructed with the aid of various DTs. A structured light laser scanner was used to digitize the nondefect patient ear. The digitized 3D ear was then manipulated in specialist software, mirrored to reflect the opposing side, and a Rapid Prototyping (RP) machine (Z-Corp) was used to manufacture the soft tissue required. This RP-mirrored ear model allows very accurate reproduction to replicate missing soft tissue. A color Spectrometer was used to accurately reproduce skin tones. The use of these technologies is now routine practice at our unit. They enhance prosthetic outcomes and esthetics, save the prosthetist's time, and are digitally stored and subsequently readily available and reproducible. PMID:22947024

  9. Cochlear Implants

    MedlinePLUS

    Cochlear Implants Cochlear Implants Patient Health Information News media interested in covering the latest from AAO-HNS/F ... treated only with a cochlear implant. How do cochlear implants work? Cochlear implants bypass damaged hair cells and ...

  10. A preliminary feasibility study of different implantable pulse generators technologies for diaphragm pacing system.

    PubMed

    Cosendai, Gregoire; de Balthasar, Chloe; Ignagni, Anthony R; Onders, Raymond P; Bradley, Kerry; Purnell, Kate; Mortimer, J Thomas; Davis, Ross; Zilberman, Yitzhak; Schulman, Joe

    2005-07-01

    Diaphragm pacing stimulation (DPS) for ventilator-dependent patients provides several advantages over conventional techniques such as phrenic nerve pacing or mechanical ventilator support. To date, the only existing system for DPS uses lead electrodes, percutaneously attached to an external pulse generator (PG). However, for a widespread use of this technique it would be more appropriate to eliminate the need for percutaneous wire and use a totally implantable system. The aim of this study was to determine if it were feasible to replace the external PG by an implantable system. We present here the results of a preliminary study of two different PG, currently used in other electrical stimulation (ES) clinical applications, which could be used as implantable DPS systems. One radio-frequency-powered PG, one rechargeable battery-powered PG, and the current external PG were tested. Each was attached to the externalized part of the wires, connected to the diaphragm and tidal volume (TV) was measured in one ventilator-dependent patient who has been using the current percutaneous stimulator for 3 years. Results indicated that both implantable PGs could achieve equivalent ventilatory requirements to the current external stimulator. No significant differences were observed between the three PG systems when stimulating the electrodes as used in the patient's own chronically attached PG system. We found that TV increased with increases in charge and frequency as expected when stimulating the patient's electrodes individually and in combination with each PG system. These results are a significant step toward developing a totally implantable DPS system for the ventilator-dependant patients. Further clinical tests to demonstrate the safety and efficacy of a fully implanted DPS system are warranted. PMID:22151497

  11. The controlled-releasing drug implant based on the three dimensional printing technology: Fabrication and properties of drug releasing in vivo

    Microsoft Academic Search

    Weigang Wu; Qixin Zheng; Xiaodong Guo; Weidong Huang

    2009-01-01

    Three dimensional (3D) printing technology was utilized to fabricate a new type of drug implant with complicated architectures,\\u000a employing levofloxacin (LVFX) and rifampicine (RFP) as model drugs. The prepared drug implant prototype consists of a double-layer\\u000a structure, of which the upper region is a reservoir system containing RFP and the lower region is a matrix one containing\\u000a LVFX. The release

  12. Polymeric heart valves for surgical implantation, catheter-based technologies and heart assist devices.

    PubMed

    Bezuidenhout, Deon; Williams, David F; Zilla, Peter

    2015-01-01

    Efficient function and long-term durability without the need for anticoagulation, coupled with the ability to be accommodated in many different types of patient, are the principal requirements of replacement heart valves. Although the clinical use of valves appeared to have remained steady for several decades, the evolving demands for the elderly and frail patients typically encountered in the developed world, and the needs of much younger and poorer rheumatic heart disease patients in the developing world have now necessitated new paradigms for heart valve technologies and associated materials. This includes further consideration of durable elastomeric materials. The use of polymers to produce flexible leaflet valves that have the benefits of current commercial bioprosthetic and mechanical valves without any of their deficiencies has been held desirable since the mid 1950s. Much attention has been focused on thermoplastic polyurethanes in view of their generally good physico-chemical properties and versatility in processing, coupled with the improving biocompatibility and stability of recent formulations. Accelerated in vitro durability of between 600 and 1000 million cycles has been achieved using polycarbonate urethanes, and good resistance to degradation, calcification and thrombosis in vivo has been shown with some polysiloxane-based polyurethanes. Nevertheless, polymeric valves have remained relegated to use in temporary ventricular assist devices for bridging heart failure patients to transplantation. Some recent studies suggest that there is a greater degree of instability in thermoplastic materials than hitherto believed so that significant challenges remain in the search for the combination of durability and biocompatibility that would allow polymeric valves to become a clinical reality for surgical implantation. Perhaps more importantly, they could become candidates for use in situations where minimally invasive transcatheter procedures are used to replace diseased valves. Being amenable to relatively inexpensive mass production techniques, the attainment of this goal could benefit very large numbers of patients in developing and emerging countries who currently have no access to treatment for rheumatic heart disease that is so prevalent in these areas. This review discusses the evolution and current status of polymeric valves in wide-ranging circumstances. PMID:25443788

  13. REFLEXIONS DE CARA AL PROCÉS D'IMPLANTACIÓ DELS ECTS EN BASE AL CONEIXEMENT DELS PROCESSOS D'ENSENYAMENT-APRENENTATGE ACTUALS

    Microsoft Academic Search

    T. Cambras; A. Díez-Noguera; J. J. Moreno; V. Martínez; M. Mitjans; M. P. Vinardell; Departament de Fisiologia; Facultat de Farmacia

    The implantation of the ECTS as a way of measuring student workload is a challenge both for professors and for students, since it implies a change not only in the methodology used in the current teaching-learning processes but also in the mentality of both teachers and learners. The new system implies a much narrower interaction between the tasks programmed by

  14. Design and simulation of an implantable medical drug delivery system using microelectromechanical systems technology

    Microsoft Academic Search

    Li Cao; Susan Mantell; Dennis Polla

    2001-01-01

    A unique design of an implantable micropump for medical drug delivery systems was proposed. The peristaltic pumping principle was selected. Three pump chambers are individually actuated by each bulk PZT (lead zirconate titanate) disk in a peristaltic motion. It is this peristaltic motion that propels the fluid. The design of the micropump includes inlet, three pump chambers, three silicon membranes,

  15. Buried ultra-low-energy gate implants for sub-0.25 micron CMOS technology

    Microsoft Academic Search

    J. Bevk; S. Kuehne; H. Vaidya; W. Mansfield; G. Hobler; D. M. Boulin; K. Bolan; C. P. Chang; K. P. Cheung; R. Cirelli; J. I. Colonell; J. Frackoviak; M. Frei; C. Gruensfelder; D. C. Jacobson; R. W. Key; F. P. Klemens; W. Y. C. Lai; J. T.-C. Lee; C. T. Liu; R. Liu; M. Oh; H. L. Maynard; D. P. Monroe; O. Nalamasu; C. S. Pai; R. Santiesteban; P. J. Silverman; W. W. Tai; A. Timko; H. Vuong; G. P. Watson; M. J. Thoma; J. T. Clemens; S. J. Hillenius

    1998-01-01

    Summary form only given. We have demonstrated that the threshold voltage shifts in closely spaced, dual-poly CMOS devices are virtually eliminated by using buried, low energy gate implants. The reduced thermal budget for gate activation, made possible by short diffusion distances, not only reduces dopant lateral diffusion in the gates but also in the device channel regions. Moreover, the process

  16. ECT in dissociative identity disorder and comorbid depression.

    PubMed

    DeBattista, C; Solvason, H B; Spiegel, D

    1998-12-01

    Dissociative identity disorder (DID), previously named multiple personality disorder, is a diagnosis often complicated by comorbid major depression. We report on four cases of DID associated with severe self-destructive behavior and comorbid major depression treated with electroconvulsive therapy (ECT). In three of the patients, ECT appeared to be helpful in treating the comorbid depression without adversely affecting the DID. The potential risks of using ECT in patients with DID are reviewed. PMID:9871851

  17. Cochlear Implants

    MedlinePLUS

    ... and Medical Procedures Implants and Prosthetics Cochlear Implants Cochlear Implants View movie of the normal ear, ear with hearing loss, and cochlear implant procedure (Requires Flash Player - Download now ) Welcome to ...

  18. Dental Implants

    MedlinePLUS

    Dental Implants A fuller, more complete smile is within reach. The following information is designed to provide helpful ... whether dental implants are right for your situation. Dental Implants and Roots The key benefit of dental implants ...

  19. \\Nonlocal" interference e ects in frequency Miloslav Dusek

    E-print Network

    Dusek, Miloslav

    \\Nonlocal" interference e ects in frequency domain Miloslav Dusek Department of Optics, Palacky It is a well known fact that interference is observable as a variation of intensity only when the path di. Nevertheless, interference e ects do not vanish in such case, but they manifest themselves as a modulation

  20. A Multimodal Tomography System Based on ECT Sensors

    Microsoft Academic Search

    Qussai Marashdeh; Warsito Warsito; Liang-Shih Fan; Fernando L. Teixeira

    2007-01-01

    A new noninvasive system for multimodal electrical tomography based on electrical capacitance tomography (ECT) sensor hardware is proposed. Quasistatic electromagnetic fields are produced by ECT sensors and used for interrogating the sensing domain. The new system is noninvasive and based on capacitance measurements for permittivity and power balance measurements for conductivity (impedance) imaging. A dual sensitivity map of perturbations in

  1. ECTS -EUROPEAN CREDIT TRANSFER SYSTEM EUROPISCHES SYSTEM ZUR ANRECHNUNG VON STUDIENLEISTUNGEN

    E-print Network

    Haller-Dintelmann, Robert

    ECTS - EUROPEAN CREDIT TRANSFER SYSTEM EUROPÄISCHES SYSTEM ZUR ANRECHNUNG VON STUDIENLEISTUNGEN package Bezeichnung des Kurses (laut Informationspaket) / Course unit title (as indicated in the information package) Anzahl der ECTS- Anrechnungspunkte / Number of ECTS-credits Unterschrift des

  2. Acute bilateral ECT in a depressed patient with a hip-aztreonam-spacer and subsequent maintenance ECT after prosthesis collocation.

    PubMed

    Gálvez, Verònica; de Arriba Arnau, Aida; Martínez-Amorós, Erika; Ribes, Carmina; Urretavizcaya, Mikel; Cardoner, Narcís

    2014-11-10

    ABSTRACT Electroconvulsive Therapy (ECT) has been demonstrated to be a safe and effective treatment for geriatric depression, although its application might be challenging when medical comorbidities exist. The present case reports a 78-year-old man diagnosed with recurrent unipolar major depressive disorder (MDD), who presented with a severe depressive episode with psychotic features (DSM IV). He successfully received a course of bitemporal (BT) ECT with a hip-aztreonam-spacer due to a hip fracture that occurred during hospitalization. This was followed by maintenance ECT (M-ECT) with a recent prosthesis collocation. This particular case illustrates the importance of a multidisciplinary approach in geriatric patients with somatic complications receiving ECT. PMID:25381759

  3. Multichannel implantable telemetry system

    NASA Technical Reports Server (NTRS)

    Fryer, T. B.; Mccutcheon, E. P.; Sandler, H.; Freund, W.

    1977-01-01

    Multiplexed biotelemetry system for animal research combines several power-saving features. Implantable sensor measures up to eight parameters simultaneously, including blood flow. Microamp transistors, switching circuits, and CMOS technology are used to lower power requirements. However, when blood flow is monitored, these measures are insufficient to reduce power enough for long-term operation from implantable primary battery.

  4. Informed consent and ECT: how much information should be provided?

    PubMed

    Torrance, Robert

    2015-05-01

    Obtaining informed consent before providing treatment is a routine part of modern clinical practice. For some treatments, however, there may be disagreement over the requirements for 'informed' consent. Electroconvulsive therapy (ECT) is one such example. Blease argues that patients 'should surely be privy to the matters of fact that: (1) there is continued controversy over the effectiveness of ECT; (2) there is orthodox scientific consensus that there is currently no acknowledged explanation for ECT and (3) there is a serious (mainstream) debate over whether the response to ECT may be a placebo response.' Before embracing these suggestions, two key questions must be asked. Are these claims a reasonable representation of current ECT research? And if so, will this information be of benefit to patients? The evidence-based support for ECT from both National Institute for Health and Care Excellence and the Royal College of Psychiatrists appears to undermine the validity of claims (1) and (3), and therefore the rationale for providing this information. Concerning assertion (2), it is true that the mechanism by which ECT has its therapeutic effect is not yet established, although the importance of conveying this fact to the patient is questionable. Of greater certainty is that the same irresolution surrounds the mechanism of action of pharmaceutical antidepressants, and so a double standard in patient care should be mindfully avoided if provision of this information is deemed a prerequisite for proper 'informed' consent. PMID:24938322

  5. Cochlear Implants.

    ERIC Educational Resources Information Center

    Clark, Catherine; Scott, Larry

    This brochure explains what a cochlear implant is, lists the types of individuals with deafness who may be helped by a cochlear implant, describes the process of evaluating people for cochlear implants, discusses the surgical process for implanting the aid, traces the path of sound through the cochlear implant to the brain, notes the costs of…

  6. Cochlear implantation: a biomechanical prosthesis for hearing loss

    PubMed Central

    Yawn, Robert; Hunter, Jacob B.; Sweeney, Alex D.

    2015-01-01

    Cochlear implants are a medical prosthesis used to treat sensorineural deafness, and one of the greatest advances in modern medicine. The following article is an overview of cochlear implant technology. The history of cochlear implantation and the development of modern implant technology will be discussed, as well as current surgical techniques. Research regarding expansion of candidacy, hearing preservation cochlear implantation, and implantation for unilateral deafness are described. Lastly, innovative technology is discussed, including the hybrid cochlear implant and the totally implantable cochlear implant. PMID:26097718

  7. Using thiamine to reduce post-ECT confusion.

    PubMed

    Linton, C R; Reynolds, M T P; Warner, N J

    2002-02-01

    Cognitive side-effects are commonly seen following electroconvulsive therapy which convey no therapeutic benefit but are troublesome to both patient and clinician. Various efforts have been made in the past to minimize these symptoms. Although modification of technical parameters related to ECT administration has led to some limited improvement in this regard, attention is now being increasingly focussed on pharmacological approaches. A number of agents have been explored in this context, however, as far as we are aware, the use of thiamine has not yet been investigated. We present three cases of elderly patients undergoing ECT for major depression in whom thiamine administration was associated with beneficial effects on post-ECT confusion. We review the evidence suggesting that thiamine deficiency may be implicated in the confusional state following ECT and recommend that consideration be given to its use in preventing and treating this problematic side-effect, especially in elderly patients. PMID:11813284

  8. The use of ECT and MST in treating depression.

    PubMed

    Allan, Charlotte L; Ebmeier, Klaus P

    2011-10-01

    Electroconvulsive therapy (ECT) has been used clinically since 1938. Its most common use is in the treatment of depression: first line treatment where rapid recovery is a priority, but more frequently as an effective treatment for patients who do not respond to pharmacological and psychological approaches. Whilst it is widely hailed as an effective treatment, concerns about its effect on cognition remain. The development of magnetic seizure therapy (MST) over the past decade has attempted to devise a therapy with comparable efficacy to ECT, but without the associated cognitive side effects. The rationale for this is that MST uses magnetic fields to induce seizures in the cortex, without electrical stimulation of brain structures involved with memory. MST has been used successfully in the treatment of depression, yet there is a dearth of literature in comparison with ECT. We present a systematic review of the literature on ECT (from 2009-2011) and MST (from 2001-2011). PMID:22200130

  9. Sporadic encephalitis lethargica: a case treated successfully with ECT.

    PubMed

    Dekleva, K B; Husain, M M

    1995-01-01

    A patient who presented with seizures, opisthotonos, catatonia, and autonomic dysfunction developed features consistent with sporadic encephalitis lethargica. She received a course of ECT and had full recovery. PMID:7626970

  10. Evaluation of ECT reliability for axial ODSCC in steam generator tubes

    Microsoft Academic Search

    Jae Bong Lee; Jai Hak Park; Hong Deok Kim; Han Sub Chung

    2010-01-01

    The integrity of steam generator tubes is usually evaluated based on eddy current test (ECT) results. Because detection capacity of the ECT is not perfect, all of the physical flaws, which actually exist in steam generator tubes, cannot be detected by ECT inspection. Therefore it is very important to analyze ECT reliability in the integrity assessment of steam generators.The reliability

  11. Engineering the heart: Evaluation of conductive nanomaterials for improving implant integration and cardiac function

    NASA Astrophysics Data System (ADS)

    Zhou, Jin; Chen, Jun; Sun, Hongyu; Qiu, Xiaozhong; Mou, Yongchao; Liu, Zhiqiang; Zhao, Yuwei; Li, Xia; Han, Yao; Duan, Cuimi; Tang, Rongyu; Wang, Chunlan; Zhong, Wen; Liu, Jie; Luo, Ying; (Mengqiu) Xing, Malcolm; Wang, Changyong

    2014-01-01

    Recently, carbon nanotubes together with other types of conductive materials have been used to enhance the viability and function of cardiomyocytes in vitro. Here we demonstrated a paradigm to construct ECTs for cardiac repair using conductive nanomaterials. Single walled carbon nanotubes (SWNTs) were incorporated into gelatin hydrogel scaffolds to construct three-dimensional ECTs. We found that SWNTs could provide cellular microenvironment in vitro favorable for cardiac contraction and the expression of electrochemical associated proteins. Upon implantation into the infarct hearts in rats, ECTs structurally integrated with the host myocardium, with different types of cells observed to mutually invade into implants and host tissues. The functional measurements showed that SWNTs were essential to improve the performance of ECTs in inhibiting pathological deterioration of myocardium. This work suggested that conductive nanomaterials hold therapeutic potential in engineering cardiac tissues to repair myocardial infarction.

  12. EEG effects of ECT: implications for rTMS.

    PubMed

    Krystal, A D; West, M; Prado, R; Greenside, H; Zoldi, S; Weiner, R D

    2000-01-01

    Electroconvulsive therapy (ECT) involves the use of electrical stimulation to elicit a series of generalized tonic-clonic seizures for therapeutic purposes and is the most effective treatment known for major depression. These treatments have significant neurophysiologic effects, many of which are manifest in the electroencephalogram (EEG). The relationship between EEG data and the response to ECT has been studied since the 1940s, but for many years no consistent correlates were found. Recent studies indicate that a number of specific EEG features recorded during the induced seizures (ictal EEG) as well as before and after a course of treatment (interictal EEG) are related to both the therapeutic efficacy and cognitive side effects. Similar to ECT, repetitive transcranial magnetic stimulation (rTMS), which involves focal electromagnetic stimulation of cortical neurons, has also been studied as an antidepressant therapy and also appears to have neurophysiologic effects, although these have not been as fully investigated as is the case with ECT. Given the similarity of these treatments, it is natural to consider whether advances in understanding the electrophysiologic correlates of the ECT response might have implications for rTMS. The present article reviews the literature on the EEG effects of ECT and discusses the implications in terms of the likely efficacy and side effects associated with rTMS in specific anatomic locations, the potential for producing an antidepressant response with rTMS without eliciting seizure activity, eliciting focal seizures with rTMS, and the possibility of using rTMS to focally modulate seizure induction and spread with ECT to optimize treatment. PMID:11126190

  13. Selfprotective smart orthopedic implants.

    PubMed

    Parvizi, Javad; Antoci, Valentin; Hickok, Noreen J; Shapiro, Irving M

    2007-01-01

    In this review, we discuss current advances leading to an exciting change in implant design for orthopedic surgery. The initial biomaterial approaches in implant design are being replaced by cellular-molecular interactions and nanoscale chemistry. New designs address implant complications, particularly loosening and infection. For infection, local delivery systems are an important first step in the process. Selfprotective 'smart' devices are an example of the next generation of orthopedic implants. If proven to be effective, antibiotics or other active molecules that are tethered to the implant surface through a permanent covalent bond and tethering of antibiotics or other biofactors are likely to transform the practice of orthopedic surgery and other medical specialties. This new technology has the potential to eliminate periprosthetic infection, a major and growing problem in orthopedic practice. PMID:17187471

  14. Placing Dental Implants

    MedlinePLUS

    Placing Dental Implants Before Placing an Implant Placing the Implants Complications from Surgery Implant Failure When you get implants, more ... Implant Most people are good candidates to get dental implants. You must have enough bone in your jaw ...

  15. Prosthodontic management of implant therapy.

    PubMed

    Thalji, Ghadeer; Bryington, Matthew; De Kok, Ingeborg J; Cooper, Lyndon F

    2014-01-01

    Implant-supported dental restorations can be screw-retained, cement-retained, or a combination of both, whereby a metal superstructure is screwed to the implants and crowns are individually cemented to the metal frame. Each treatment modality has advantages and disadvantages. The use of computer-aided design/computer-assisted manufacture technologies for the manufacture of implant superstructures has proved to be advantageous in the quality of materials, precision of the milled superstructures, and passive fit. Maintenance and recall evaluations are an essential component of implant therapy. The longevity of implant restorations is limited by their biological and prosthetic maintenance requirements. PMID:24286654

  16. Defibrillator Function and Implantation

    Microsoft Academic Search

    Robert E. Eckart; Jane Chen; Laurence M. Epstein

    The development of the implantable cardioverter-defibrillator (ICD) is primarily the result of pioneering work by Michel Mirowski.\\u000a First-generation devices consisted of a large generator placed in an abdominal pocket capable only of high-energy shocks.\\u000a In the 25 years since the first implantation in humans (1), advances in technology have resulted in significantly smaller\\u000a devices, with sophisticated detection algorithms and tiered

  17. The ObjECTS: Framework for Integrated Assessment: Hybrid Modeling of Transportation

    SciTech Connect

    Kim, Son H.; Edmonds, James A.; Lurz, Joshua; Smith, Steven J.; Wise, Marshall A.

    2006-09-01

    Technology is a central issue for the global climate change problem, requiring analysis tools that can examine the impact of specific technologies with a long-term, global context. This paper describes the architecture of the ObjECTS-MiniCAM integrated assessment model, which implements a long-term, global model of energy, economy, agriculture, land-use, atmosphere, and climate change in a framework that allows the flexible incorporation of explicit technology detail. We describe the implementation of a ''bottom-up'' representation of the transportation sector as an illustration of this approach, in which the resulting hybrid model is fully integrated, internally consistent and theoretically compatible with the regional and global modeling framework. The analysis of the transportation sector presented here supports and clarifies the need for a comprehensive strategy promoting advanced vehicle technologies and an economy-wide carbon policy to cost-effectively reduce carbon emissions from the transportation sector in the long-term.

  18. Budapest University of Technology and Economics An ECTS Guide

    E-print Network

    Ráth, Balázs

    @yahoo.fr China Grand Education Group Dawn Zhang Room 720 Quingdao, World Trade Center, Building B, No.6 not only on our responsiveness to the needs of a continuously changing world, but also on more than 225 pro- fessors and students from all over the world. We are proud of our international professors

  19. Cochlear implant

    MedlinePLUS

    ... antenna. This part of the implant receives the sound, converts the sound into an electrical signal, and sends it to ... implants allow deaf people to receive and process sounds and speech. However, it is important to understand ...

  20. Core repulsion e ects in alkali trimers R. Gu erout

    E-print Network

    Recanati, Catherine

    Core repulsion e#11;ects in alkali trimers R. Gu#19;erout Laboratoire Aim#19;e Cotton, CNRS, B was entitled "Electronic structure properties of alkali dimers and trimers. Prospects for alignment separation, involved when the potential energy surfaces of alkali trimers are calculated with a quantum

  1. Does parasympathetic modulation prior to ECT treatment influence therapeutic outcome?

    Microsoft Academic Search

    Andreas Ebert; Thomas Jochum; Julia Ritter; Michael Karl Boettger; Steffen Schulz; Andreas Voss; Karl-Jürgen Bär

    2010-01-01

    Electroconvulsive therapy (ECT) is an established treatment option for major depressive disorder when other treatments have failed. However, the underlying mechanisms responsible for these therapeutical effects are insufficiently understood to date. Furthermore, treatment outcome is difficult to predict. Recent research suggested an important role of autonomic modulation for successful treatment.We aimed to examine putative associations between autonomic modulation and response

  2. Optical absorption spectra and geometric e ects in higher fullerenes

    E-print Network

    Harigaya, Kikuo

    Optical absorption spectra and geometric e ects in higher fullerenes (Running head: Optical absorption in higher fullerenes) Kikuo Harigaya and Shuji Abe Physical Science Division, Electrotechnical of their amplitudes at the pentagons. The oscillator strengths of projected absorption almost accord with those

  3. ccsd00002305, Tidal gravitational e ects in a satellite.

    E-print Network

    that new experiments take place in free falling (or nearly free falling) satellites. A laser cooled atomicccsd­00002305, version 1 ­ 23 Jul 2004 Tidal gravitational e#11;ects in a satellite. Ph. Tourrenc pointing towards a faraway star in a nearly free falling satellite. Such a device is sensitive

  4. ‘Side effects’ of ECT are mainly depressive phenomena and are independent of age

    Microsoft Academic Search

    Henry Brodaty; David Berle; Ian Hickie; Catherine Mason

    2001-01-01

    Background: The aetiology of reported side effects of electroconvulsive therapy (ECT) is unclear. We examined the interaction of depression and age on adverse neuropsychological and putative side effects of ECT. Method: Inpatients (N=81; median age 70 years) with major depression were assessed prospectively pre-ECT, immediately post-ECT and 1–3 years later. Patients were administered the Hamilton Rating Scale for Depression (HRSD),

  5. The Structure of Charm Jets and the Dead Cone E#ect in

    E-print Network

    The Structure of Charm Jets and the Dead Cone E#ect in Deep­Inelastic Scattering at HERA­ diation from heavy quarks, the so­called ''Dead Cone'' e#ect, predicted by QCD. In all distributions di in order to get a better understanding of the contribution from the ''Dead Cone'' e#ect to the # 0 E Jet vs

  6. Peri-Implant Diseases

    MedlinePLUS

    ... Gum Disease Regenerative Procedures Dental Crown Lengthening Procedure Dental Implants Single Tooth Implants Multiple Tooth Implants Full Mouth Dental Implants Sinus Augmentation Ridge Modification Periodontal Pocket Reduction Procedures ...

  7. High Productivity Implantation ''PARTIAL IMPLANT''

    SciTech Connect

    Hino, Masayoshi; Miyamoto, Naoki; Sakai, Shigeki; Matsumoto, Takao [Nissin Ion Equipment Co., LTD., Kyoto (Japan)

    2008-11-03

    The patterned ion implantation 'PARTIAL IMPLANT' has been developed as a productivity improvement tool. The Partial Implant can form several different ion dose areas on the wafer surface by controlling the speed of wafer moving and the stepwise rotation of twist axis. The Partial Implant system contains two implant methods. One method is 'DIVIDE PARTIAL IMPLANT', that is aimed at reducing the consumption of the wafer. The Divide Partial Implant evenly divides dose area on one wafer surface into two or three different dose part. Any dose can be selected in each area. So the consumption of the wafer for experimental implantation can be reduced. The second method is 'RING PARTIAL IMPLANT' that is aimed at improving yield by correcting electrical characteristic of devices. The Ring Partial Implant can form concentric ion dose areas. The dose of wafer external area can be selected to be within plus or minus 30% of dose of wafer central area. So the electrical characteristic of devices can be corrected by controlling dose at edge side on the wafer.

  8. Breast Implants

    MedlinePLUS

    ... filled breast implants, including data supporting a reasonable assurance of safety and effectiveness, approval letters, labeling and information on post-approval studies. Provide information on reports ...

  9. Ion Implantation

    NASA Astrophysics Data System (ADS)

    Langouche, G.; Yoshida, Y.

    In this tutorial we describe the basic principles of the ion implantation technique and we demonstrate that emission Mössbauer spectroscopy is an extremely powerful technique to investigate the atomic and electronic configuration around implanted atoms. The physics of dilute atoms in materials, the final lattice sites and their chemical state as well as diffusion phenomena can be studied. We focus on the latest developments of implantation Mössbauer spectroscopy, where three accelerator facilities, i.e., Hahn-Meitner Institute Berlin, ISOLDE-CERN and RIKEN, have intensively been used for materials research in in-beam and on-line Mössbauer experiments immediately after implantation of the nuclear probes.

  10. Drug Delivery: Enabling Technology for Drug Discovery and Development. iPRECIO® Micro Infusion Pump: Programmable, Refillable, and Implantable

    PubMed Central

    Tan, Tsung; Watts, Stephanie W.; Davis, Robert Patrick

    2011-01-01

    Successful drug delivery using implantable pumps may be found in over 12,500 published articles. Their versatility in delivering continuous infusion, intermittent or complex infusion protocols acutely or chronically has made them ubiquitous in drug discovery and basic research. The recent availability of iPRECIO®, a programmable, refillable, and implantable infusion pump has made it possible to carry out quantitative pharmacology (PKPD) in single animals. When combined with specialized catheters, specific administration sites have been selected. When combined with radiotelemetry, the physiologic gold standard, more sensitive and powerful means of detecting drug induced therapeutic, and/or adverse effects has been possible. Numerous application examples are cited from iPRECIO® use in Japan, United States, and Europe with iPRECIO® as an enabling drug delivery device where the refillable and programmability functionality were key benefits. The ability to start/stop drug delivery and to have control periods prior dosing made it possible to have equivalent effects at a much lower dose than previously studied. Five different iPRECIO® applications are described in detail with references to the original work where the implantable, refillable, and programmable benefits are demonstrated with their different end-points. PMID:21863140

  11. Drug Delivery: Enabling Technology for Drug Discovery and Development. iPRECIO Micro Infusion Pump: Programmable, Refillable, and Implantable.

    PubMed

    Tan, Tsung; Watts, Stephanie W; Davis, Robert Patrick

    2011-01-01

    Successful drug delivery using implantable pumps may be found in over 12,500 published articles. Their versatility in delivering continuous infusion, intermittent or complex infusion protocols acutely or chronically has made them ubiquitous in drug discovery and basic research. The recent availability of iPRECIO(®), a programmable, refillable, and implantable infusion pump has made it possible to carry out quantitative pharmacology (PKPD) in single animals. When combined with specialized catheters, specific administration sites have been selected. When combined with radiotelemetry, the physiologic gold standard, more sensitive and powerful means of detecting drug induced therapeutic, and/or adverse effects has been possible. Numerous application examples are cited from iPRECIO(®) use in Japan, United States, and Europe with iPRECIO(®) as an enabling drug delivery device where the refillable and programmability functionality were key benefits. The ability to start/stop drug delivery and to have control periods prior dosing made it possible to have equivalent effects at a much lower dose than previously studied. Five different iPRECIO(®) applications are described in detail with references to the original work where the implantable, refillable, and programmable benefits are demonstrated with their different end-points. PMID:21863140

  12. Biomimetic implant coatings

    Microsoft Academic Search

    E. Eisenbarth; D. Velten; J. Breme

    2007-01-01

    Biomaterials and tissue engineering technologies are becoming increasingly important in biomedical practice, particularly as the population ages. Cellular responses depend on topographical properties of the biomaterial at the nanometer scale. Structures on biomaterial surfaces are used as powerful tools to influence or even control interactions between implants and the biological system [Kawahara, H., Soeda, Y., Niwa, K., Takahashi, M., Kawahara,

  13. Ion implantation of semiconductors

    Microsoft Academic Search

    J. S. Williams

    1998-01-01

    Ion implantation was first applied to semiconductors over 30 years ago as a means of introducing controllable concentrations of n- and p-type dopants at precise depths below the surface. It is now an indispensable process in the manufacture of integrated circuits. This review gives a brief and selected overview of ion beam modification of semiconductors, treating both fundamental and technological

  14. ePUB: Modellierung Molecular Life Sciences Master Major 90 ECTS-Credits with special qualification in Microbio/

    E-print Network

    Richner, Heinz

    to write in English (2.00 ECTS) (Wahlpflichtprüfung) (WS05/06 bis HS07) Advanced medicinal chemistry - from.50 ECTS) (Wahlpflichtprüfung) (ab HS09) Basic medicinal chemistry - principles of drug action (1.50 ECTS) (Wahlpflichtprüfung) (ab FS09) Blutplasmaproteine (1.50 ECTS) (Wahlpflichtprüfung) Cell and molecular biology journal

  15. Implantable Heart Aid

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Medrad utilized NASA's Apollo technology to develop a new device called the AID implantable automatic pulse generator which monitors the heart continuously, recognizes the onset of ventricular fibrillation and delivers a corrective electrical shock. AID pulse generator is, in effect, a miniaturized version of the defibrillator used by emergency squads and hospitals to restore rhythmic heartbeat after fibrillation, but has the unique advantage of being permanently available to the patient at risk. Once implanted, it needs no specially trained personnel or additional equipment. AID system consists of a microcomputer, a power source and two electrodes which sense heart activity.

  16. Semiconductor Ion Implanters

    NASA Astrophysics Data System (ADS)

    MacKinnon, Barry A.; Ruffell, John P.

    2011-06-01

    In 1953 the Raytheon CK722 transistor was priced at 7.60. Based upon this, an Intel Xeon Quad Core processor containing 820,000,000 transistors should list at 6.2 billion! Particle accelerator technology plays an important part in the remarkable story of why that Intel product can be purchased today for a few hundred dollars. Most people of the mid twentieth century would be astonished at the ubiquity of semiconductors in the products we now buy and use every day. Though relatively expensive in the nineteen fifties they now exist in a wide range of items from high-end multicore microprocessors like the Intel product to disposable items containing `only' hundreds or thousands like RFID chips and talking greeting cards. This historical development has been fueled by continuous advancement of the several individual technologies involved in the production of semiconductor devices including Ion Implantation and the charged particle beamlines at the heart of implant machines. In the course of its 40 year development, the worldwide implanter industry has reached annual sales levels around 2B, installed thousands of dedicated machines and directly employs thousands of workers. It represents in all these measures, as much and possibly more than any other industrial application of particle accelerator technology. This presentation discusses the history of implanter development. It touches on some of the people involved and on some of the developmental changes and challenges imposed as the requirements of the semiconductor industry evolved.

  17. Histrelin Implant

    MedlinePLUS

    ... used to treat the symptoms associated with advanced prostate cancer. Histrelin implant (Supprelin LA) is used to ... to use certain tests, such as ultrasound or MRI scans (radiology techniques designed to show the images ...

  18. QuECT: A New Quantum Programming Paradigm

    E-print Network

    Chakraborty, Arnab

    2011-01-01

    Quantum computation constitutes a rapidly expanding subfield of computer science. Development quantum algorithms is facilitated by the availability of efficient quantum programming languages, and a plethora of approaches has been already suggested in the literature, ranging from GUI-based simple tools to elaborate standalone programming languages. In this paper we propose a novel paradigm called Quantum Embeddable Circuit Technique (QuECT) that allows a programmer to embed a circuit diagram in a classical "host" language. The paradigm can be implemented in any modern classical language. A prototype has been developed by the author using Java.

  19. QuECT: A New Quantum Programming Paradigm

    E-print Network

    Arnab Chakraborty

    2011-04-04

    Quantum computation constitutes a rapidly expanding subfield of computer science. Development quantum algorithms is facilitated by the availability of efficient quantum programming languages, and a plethora of approaches has been already suggested in the literature, ranging from GUI-based simple tools to elaborate standalone programming languages. In this paper we propose a novel paradigm called Quantum Embeddable Circuit Technique (QuECT) that allows a programmer to embed a circuit diagram in a classical "host" language. The paradigm can be implemented in any modern classical language. A prototype has been developed by the author using Java.

  20. Danger: implants.

    PubMed

    Findlay, S; Podolsky, D

    1992-08-24

    The superheated debate over breast implants awakened a sleeping giant of an issue clouding "medical devices"--the government's clumsy nomenclature for any medical product that is not a drug, from breast implants and artificial hips to X-ray machines and surgical thread. Some 130 categories of high-risk devices are in use with little or no proof of safety, reliability or effectiveness. All appeared before 1976, the year that the Food and Drug Administration got the authority to regulate such products. Under activist chief David Kessler and with added clout from a 1990 law, the FDA plans to scrutinize the entire 130-item list. Five will get special attention starting early next year: saline-filled breast implants, inflatable penile implants, testicular implants, heart-bypass pumps and cranial stimulators. U.S. News has looked at all five devices, using FDA data obtained through the Freedom of Information Act. In-depth computer analysis suggested that penile implants deserve closer examination. Why is clear from the following report. PMID:10171242

  1. An image reconstruction method by deconvolution for ECT

    NASA Astrophysics Data System (ADS)

    Sasamoto, Akira; Suzuki, Takayuki; Nishimura, Yoshihiro

    2008-03-01

    Eddy Current Testing(ECT) has been used in wide field such as airline and power plants for maintenance, ironworks for production. However original flaw shape blur in image by signal of ECT. In our previous work an image reconstruction method from signal had been proposed. The method is based on that simple relationship between signal and source are described by a convolution of response function and flaw shape. The method was able to show more fine image of points flaw, short line flaw, long line flaw than images of those original signal. One difficulty in the method was to determine empirical parameter by trial and error. In this paper, we propose a concept of modified response function and signal that enable to make empirical parameter unnecessary. Those modification process is fully programmable and is carried out automatically. Validity of introducing those modification are considered from mathematical view point. Numerical results shows the method with this concept reconstructed image as same as empirical parameter method.

  2. Using a Cochlear Implant

    MedlinePLUS

    ... Vision Loss Using a Cochlear Implant Using a Cochlear Implant Note: This video may take several seconds to ... Cochlear Implant Video (Quicktime) Transcript of Using a Cochlear Implant Video NARRATOR: Mary, a woman with short gray ...

  3. Implantable Medical Devices

    MedlinePLUS

    Implantable Medical Devices Updated:Oct 23,2014 Implantable Medical Devices - 2 types 1. Rhythm control ICD -- Implantable cardioverter-defibrillator ( ... medical treatment. 2. Support of the Circulation Implantable Medical Devices Left Ventricular Assist Device (Also known as ...

  4. Using Problem Generators to Explore the E ects of Epistasis Kenneth A. De Jong

    E-print Network

    Using Problem Generators to Explore the E ects of Epistasis Kenneth A. De Jong Computer Science generators. We then describe three genera- tors that can be used to study the e ects of epistasis of epistasis on simple GAs. 1 Introduction Although we have made signi cant progress in recent years

  5. O.S.U.-T.C.G. Report No. 107 The Jahn-Teller E ect

    E-print Network

    Pitzer, Russell M.

    ) 177 translated by R. M. Pitzer December, 1976 Abstract A survey of ligand eld theory is given is discussed. The theory of the dynamic Jahn-Teller e ect is outlined, and theoretical and experimental results that these distortions are caused by the Jahn-Teller e ect. In a crystal lattice one must take account

  6. Speed of response in ultrabrief and brief pulse width right unilateral ECT.

    PubMed

    Loo, Colleen K; Garfield, Joshua B B; Katalinic, Natalie; Schweitzer, Isaac; Hadzi-Pavlovic, Dusan

    2013-05-01

    Ultrabrief pulse width stimulation electroconvulsive therapy (ECT) results in less cognitive side-effects than brief pulse ECT, but recent work suggests that more treatment sessions may be required to achieve similar efficacy. In this retrospective analysis of subjects pooled from three research studies, time to improvement was analysed in 150 depressed subjects who received right unilateral ECT with a brief pulse width (at five times seizure threshold) or ultrabrief pulse width (at six times seizure threshold). Multivariate Cox regression analyses compared the number of treatments required for 50% reduction in depression scores (i.e. speed of response) in these two samples. The analyses controlled for clinical, demographic and treatment variables that differed between the samples or that were found to be significant predictors of speed of response in univariate analyses. In the multivariate analysis, older age predicted faster speed of response. There was a non-significant trend for faster time to 50% improvement with brief pulse ECT (p = 0.067). Remission rates were higher after brief pulse ECT than ultrabrief pulse ECT (p = 0.007) but response rates were similar. This study, the largest of its kind reported to date, suggests that fewer treatments may be needed to attain response with brief than ultrabrief pulse ECT and that remission rates are higher with brief pulse ECT. Further research with a larger randomized and blinded study is recommended. PMID:22963997

  7. A prospective follow-up study of ECT outcome in older depressed patients

    Microsoft Academic Search

    Henry Brodaty; Ian Hickie; Catherine Mason; Leanne Prenter

    2000-01-01

    Background: This study examined the relationship between age and outcome of electroconvulsive therapy (ECT). Method: This was a naturalistic, prospective follow-up of 81 consecutive in-patients with primary major depression. ECT outcome was compared for three age groups — under 65, 65–74 and 75 years and over — on the Hamilton Rating Scale for Depression (HRSD), Global Assessment of Functioning scale

  8. OIL IN THE OPEN WATER Oil in the open water may a ect the health of

    E-print Network

    OIL IN THE OPEN WATER Oil in the open water may a ect the health of microscopic plants and animals. Far beneath the surface, corals and other deepwater communities might also be a ected. OIL AND HUMAN AND SEDIMENTS · Water quality surveys · Transect surveys to detect submerged oil · Oil plume modeling · Sediment

  9. The E ect of Barriers on The Tidal Range in Yong Ming Tang

    E-print Network

    The E ect of Barriers on The Tidal Range in Estuaries Yong Ming Tang Abstract Numerical simulations in estuaries. The results show that the nonlinear advection terms in the momentumequations play very little is todescribe the e ect of topographic barriers on the tidal range in large estuaries, using numerical

  10. Ion Implant

    NSDL National Science Digital Library

    This website includes an animation which illustrates the ion implant process. Objective: Name the three common dopants used in implantation processes and explain the process of generating an ion beam from source to wafer. You can find this animation under the heading "Process & Equipment III." This simulation is from Module 026 of the Process & Equipment III Cluster of the MATEC Module Library (MML). To view other clusters or for more information about the MML visit http://matec.org/ps/library3/process_I.shtmlKey

  11. Computerized implant-dentistry: Advances toward automation

    PubMed Central

    Gulati, Minkle; Anand, Vishal; Salaria, Sanjeev Kumar; Jain, Nikil; Gupta, Shilpi

    2015-01-01

    Advancements in the field of implantology such as three-dimensional imaging, implant-planning software, computer-aided-design/computer-aided-manufacturing (CAD/CAM) technology, computer-guided, and navigated implant surgery have led to the computerization of implant-dentistry. This three-dimensional computer-generated implant-planning and surgery has not only enabled accurate preoperative evaluation of the anatomic limitations but has also facilitated preoperative planning of implant positions along with virtual implant placement and subsequently transferring the virtual treatment plans onto the surgical phase via static (guided) or dynamic (navigated) systems aided by CAD/CAM technology. Computerized-implant-dentistry being highly predictable and minimally invasive in nature has also allowed implant placement in patients with medical comorbidities (e.g. radiation therapy, blood dyscrasias), in patients with complex problems following a significant alteration of the bony anatomy as a result of benign or malignant pathology of the jaws or trauma and in patients with other physical and emotional problems. With significant achievements accomplished in the field of computerized implant-dentistry, attempts are now been made toward complete automation of implant-dentistry. PMID:25810585

  12. Cochlear Implants

    MedlinePLUS

    ... during an optimal period to develop speech and language skills. A growing body of research, much of it funded by the NIDCD, has shown that when these children receive a cochlear implant ... a young age develop language skills at a rate comparable to children with ...

  13. Purinergic signaling in early inflammatory events of the foreign body response: modulating extracellular ATP as an enabling technology for engineered implants and tissues.

    PubMed

    Rhett, J Matthew; Fann, Stephen A; Yost, Michael J

    2014-10-01

    Purinergic signaling is a ubiquitous and vital aspect of mammalian biology in which purines--mainly adenosine triphosphate (ATP)--are released from cells through loss of membrane integrity (cell death), exocytosis, or transport/diffusion across membrane channels, and exert paracrine or autocrine signaling effects through three subclasses of well-characterized receptors: the P1 adenosine receptors, the P2X ionotropic nucleotide receptors, and the P2Y metabotropic receptors. ATP and its metabolites are released by damaged and stressed cells in injured tissues. The early events of wound healing, hemostasis, and inflammation are highly regulated by these signals through activation of purinergic receptors on platelets and neutrophils. Recent data have demonstrated that ATP signaling is of particular importance to targeting leukocytes to sites of injury. This is particularly relevant to the subject of implanted medical devices, engineered tissues, and grafts as all these technologies elicit a wound healing response with varying degrees of encapsulation, rejection, extrusion, or destruction of the tissue or device. Here, we review the biology of purinergic signaling and focus on ATP release and response mechanisms that pertain to the early inflammatory phase of wound healing. Finally, therapeutic options are explored, including a new class of peptidomimetic drugs based on the ATP-conductive channel connexin43. PMID:24279914

  14. Dealing with moral dilemma raised by adaptive preferences in health technology assessment: the example of growth hormones and bilateral cochlear implants.

    PubMed

    Thébaut, Clémence

    2013-12-01

    The aim of this article is to assess dilemma raised by adaptive preferences in the economic evaluation of growth hormone (GH) treatment for non-GH-deficient short children, and of bilateral cochlear implants for deaf children. Early implementation of both technologies and their irreversible consequences increase the potential conflicts faced by the assessors of health-related quality of life (HRQoL) states (on behalf of patients) who could be interviewed (parents, individuals with an experience of the same disability, or representative samples of the general public). Indeed, assessors' preferences may be influenced by their own situation and they are likely to vary according to age and the experience of disability. Three options are put forward which aim to resolve these moral dilemma and help economists make methodological choices that cannot be avoided in order to carry out this assessment. They are grounded on three specific egalitarian theories of social justice. The main contribution of this article is to show that a dialogue between ethics and economics, prior to an assessment, makes it possible to redefine the choice of effectiveness criteria (subjective well-being, capabilities or social outcomes), the choice of perspective (patients or the able-bodied), as well as the scope of assessment (medical and non-medical care). PMID:24355476

  15. A Generic Method for Distribution and Transfer of ECTS and Other Norm-Referenced Grades within Student Cohorts

    ERIC Educational Resources Information Center

    Warfvinge, Per

    2008-01-01

    The ECTS grade transfer scale is an interface grade scale to help European universities, students and employers to understand the level of student achievement. Hence, the ECTS scale can be seen as an interface, transforming local scales to a common system where A-E denote passing grades. By definition, ECTS should distribute the passing students…

  16. ePUB: Modellierung Molecular Life Sciences Master Major 90 ECTS-Credits with special qualification in Cellular and

    E-print Network

    Richner, Heinz

    medicinal chemistry - from target to drug (1.50 ECTS) (Wahlpflichtprüfung) Aktuelle Probleme der into light microscopy (0.50 ECTS) (Wahlpflichtprüfung) (ab HS09) Basic medicinal chemistry - principles) (Wahlpflichtprüfung) Cell and molecular biology journal club (2.00 ECTS) (Wahlpflichtprüfung) (HS07 bis FS10) Cellular

  17. Sub-2y node NAND flash characteristics using spot beam technology for low energy, high tilt implant for n-poly doping

    NASA Astrophysics Data System (ADS)

    Ryu, Chong-Il; Lee, Sangsun; Jeon, Young-Ho; Cheon, Youngil; Choi, Jin-Kwan; Yang, Young-Ho; Lee, Kyung-Won; Hong, Rympyo; Yoon, Jong-Yoon; Reece, Ron; Rubin, Leonard M.

    2012-11-01

    Reduction of polysilicon sheet resistivity and polysilicon depletion ratio (PDR) are two major challenges for improving the memory cell characteristics of sub-20 nm NAND Flash devices. High phosphorus doses are implanted into in situ doped polysilicon floating gates to improve PDR, but phosphorus concentrations that are too high can degrade cell characteristics by increasing trapped charge in the TNOX(Tunnel Oxide). It is also important to prevent the bending of narrow polysilicon lines during floating gate implantation. We explored various conditions of low energy, high tilt phosphorus implants for floating gate doping using a spot beam high current implanter. The optimal concentration of implant energy, tilt angle, and thermal annealing has been shown to improve PDR and floating gate TOP CD control.

  18. [Evaluation of asymetric implants in breast cancer].

    PubMed

    Fitoussi, A; Couturaud, B; Laki, F; Alran, S; Salmon, R J

    2005-10-01

    Since more than twenty years, methods of breast reconstruction using implants have continued to evolve in order to improve their aesthetic results. Shapes and materials of these implants have also evolved to obtain contours similar to that of the natural opposite breast. Therefore it can be considered that the use of asymmetric implants is the last step in implant technology before using made to measure implants. Asymmetric implants allow obtaining different contours in harmony to the different breast shapes according to the side, left or right, of the reconstructed breast which maximise the naturalness of the result. Such implants have an axis directed towards the exterior and lower part of the chest wall, are wider than high with a thinner part on their inner edge and a concave rear side moulding the curves of the chest wall. In our own experience, we placed more than 500 asymmetric implants. When analysing retrospectively the medical records of 156 patients, no distinctive features were observed when compared to symmetric classic implants in easiness in the surgical procedure or in complications except a slightly higher rate of seroma formation. When compared to usual implants the main benefits of asymmetric implants are: to offer a wider breadth, to slope down gently on their upper and inner sides according to their concave rear side, and therefore to better match subtle curves of a normal breast. Moreover such contours allow a distribution of the volume which fit better to the usual natural breast configuration of patients who underwent surgery for breast carcinoma. At last, such implants are easy to place and a very low rate of secondary rotation has been observed. In summary, for all these reasons, asymmetric implants, can be considered to be the class one in the choice of implants for breast reconstruction after breast surgery. PMID:16198040

  19. Indications and Common Surgical Approaches for Cochlear Implantation in China

    Microsoft Academic Search

    Zhengnong Chen; Dongzhen Yu; Yaqin Wu; Huiqun Zhou; Haibo Shi; Shankai Yin

    2009-01-01

    Cochlear implants have become widely used in the management of profound sensorineural hearing loss. With today’s technology and the demonstrated success of cochlear implantation, candidacy criteria have greatly widened. In this paper, we describe issues concerning the current indications and common surgical approaches to cochlear implantation in China.

  20. Shannon SHAR Chapter page 1 Speech Perception with Cochlear Implants

    E-print Network

    Allen, Jont

    Shannon SHAR Chapter page 1 Speech Perception with Cochlear Implants Robert V. Shannon Qian-Jie Fu-mail: Shannon@hei.org #12;Shannon SHAR Chapter page 2 1.0 Introduction Cochlear implants, besides restoring features found in speech. Because present cochlear implant technology cannot preserve all the acoustic

  1. The expandable mammary implant.

    PubMed

    Becker, H

    1987-04-01

    An expandable saline-gel implant having a detachable injection dome is described. The implant functions initially as a tissue expander. Once the correct size has been obtained, the injection dome is removed, leaving the implant in position. PMID:3823256

  2. Exciton e ects on optical absorption spectra of electroluminescent polymer poly(para-phenylenevinylene)

    E-print Network

    Harigaya, Kikuo

    Exciton e ects on optical absorption spectra of electroluminescent polymer poly spectra of the electroluminescent polymer poly(para-phenylenevinylene) (PPV) by using the intermediate The observation of remarkable electroluminescent properties of poly(para-phenylenevinylene) (PPV)1 has attracted

  3. Osteogenic activity and antibacterial effect of zinc ion implanted titanium.

    PubMed

    Jin, Guodong; Cao, Huiliang; Qiao, Yuqin; Meng, Fanhao; Zhu, Hongqin; Liu, Xuanyong

    2014-05-01

    Titanium (Ti) and its alloys are widely used as orthopedic and dental implants. In this work, zinc (Zn) was implanted into oxalic acid etched titanium using plasma immersion ion implantation technology. Scanning electron microscopy and X-ray photoelectron spectroscopy were used to investigate the surface morphology and composition of Zn-implanted titanium. The results indicate that the depth profile of zinc in Zn-implanted titanium resembles a Gaussian distribution, and zinc exists in the form of ZnO at the surface whereas in the form of metallic Zn in the interior. The Zn-implanted titanium can significantly stimulate proliferation of osteoblastic MC3T3-E1 cells as well as initial adhesion, spreading activity, ALP activity, collagen secretion and extracellular matrix mineralization of the rat mesenchymal stem cells. The Zn-implanted titanium presents partly antibacterial effect on both Escherichia coli and Staphylococcus aureus. The ability of the Zn-implanted titanium to stimulate cell adhesion, proliferation and differentiation as well as the antibacterial effect on E. coli can be improved by increasing implantation time even to 2 h in this work, indicating that the content of zinc implanted in titanium can easily be controlled within the safe concentration using plasma immersion ion implantation technology. The Zn-implanted titanium with excellent osteogenic activity and partly antibacterial effect can serve as useful candidates for orthopedic and dental implants. PMID:24632388

  4. BARE PCB INSPECTION BY MEAN OF ECT TECHNIQUE WITH SPIN-VALVE GMR SENSOR

    Microsoft Academic Search

    K. Chomsuwan; S. Yamada; M. Iwahara; H. Wakiwaka; T. Taniguchi; S. Shoji

    The high-sensitive micro eddy-current testing (ECT) probe composed of planar meander coil as an exciter and spin-valve giant magneto-resistance (SV-GMR) sensor as a magnetic sensor for bare printed circuit board (PCB) inspection is proposed in this paper. The high-sensitive micro ECT probe detects the magnetic field distribution on the bare PCB and the image processing technique analyzes output signal achieved

  5. Appraisal of evidence base for introduction of new implants in hip and knee replacement: a systematic review of five widely used device technologies

    PubMed Central

    Nieuwenhuijse, Marc J; Nelissen, R G H H; Schoones, J W

    2014-01-01

    Objective To determine the evidence of effectiveness and safety for introduction of five recent and ostensibly high value implantable devices in major joint replacement to illustrate the need for change and inform guidance on evidence based introduction of new implants into healthcare. Design Systematic review of clinical trials, comparative observational studies, and registries for comparative effectiveness and safety of five implantable device innovations. Data sources PubMed (Medline), Embase, Web of Science, Cochrane, CINAHL, reference lists of articles, annual reports of major registries, summaries of safety and effectiveness for pre-market application and mandated post-market studies at the US Food and Drug Administration. Study selection The five selected innovations comprised three in total hip replacement (ceramic-on-ceramic bearings, modular femoral necks, and uncemented monoblock cups) and two in total knee replacement (high flexion knee replacement and gender specific knee replacement). All clinical studies of primary total hip or knee replacement for symptomatic osteoarthritis in adults that compared at least one of the clinical outcomes of interest (patient centred outcomes or complications, or both) in the new implant group and control implant group were considered. Data searching, abstraction, and analysis were independently performed and confirmed by at least two authors. Quantitative data syntheses were performed when feasible. Results After assessment of 10?557 search hits, 118 studies (94 unique study cohorts) met the inclusion criteria and reported data related to 15?384 implants in 13?164 patients. Comparative evidence per device innovation varied from four low to moderate quality retrospective studies (modular femoral necks) to 56 studies of varying quality including seven high quality (randomised) studies (high flexion knee replacement). None of the five device innovations was found to improve functional or patient reported outcomes. National registries reported two to 12 year follow-up for revision occurrence related to more than 200?000 of these implants. Reported comparative data with well established alternative devices (over 1?200?000 implants) did not show improved device survival. Moreover, we found higher revision occurrence associated with modular femoral necks (hazard ratio 1.9) and ceramic-on-ceramic bearings (hazard ratio 1.0-1.6) in hip replacement and with high flexion knee implants (hazard ratio 1.0-1.8). Conclusion We did not find convincing high quality evidence supporting the use of five substantial, well known, and already implemented device innovations in orthopaedics. Moreover, existing devices may be safer to use in total hip or knee replacement. Improved regulation and professional society oversight are necessary to prevent patients from being further exposed to these and future innovations introduced without proper evidence of improved clinical efficacy and safety. PMID:25208953

  6. Experimental studies on electrolytic dosage of ECT for dog's oesophageal injury and clinical effects of ECT for oesophageal anastomotic opening stenosis and oesophageal carcinoma.

    PubMed

    Liu, D; Xin, Y L; Ge, B; Zhao, F; Zhso, H

    1994-01-01

    Experimental and clinical studies have been performed to explore the potential benefits of electrochemical therapy (ECT) in oesophageal cancer. In a dog experiment, the oesophageal injury induced by ECT was evaluated. The provision of 7.5 volts (V) and 25-100 coulomb (C) was associated with a slight injury of the mucosa, which was completely healed after two weeks. Ten patients with oesophageal stenosis were treated with ECT (4.5-5.5 V, 20-50 mA and 85-180 C). In all patients there was a significant dilatation of the stenotic area and the patients could eat a normal diet after three to four weeks. The clinical effectiveness in 35 patients treated with ECT for inoperable oesophagela carcinoma was found to be satisfactory. Complete and partial response was obtained in 15 cases (42.8%), and dysphagia was relieved for five to 13 months. In conclusion, oesophageal cancer may be successfully treated with a specially designed electrode and a specified dosage of electricity. PMID:7531026

  7. Approved Module Information for EE1ECT, 2014/5 Module Title/Name: Electrical Circuit Theory Module Code: EE1ECT

    E-print Network

    Neirotti, Juan Pablo

    Approved Module Information for EE1ECT, 2014/5 Module Title/Name: Electrical Circuit Theory Module techniques of electrical circuits to enable higher level study on electronic and communication subjects. The module will concentrate on the fundamentals of electrical DC and AC circuits with particular applications

  8. Electronic Communications Technologies and the Transition to College: Links to Parent-Child Attachment and Adjustment

    ERIC Educational Resources Information Center

    Sarigiani, Pamela A.; Trumbell, Jill M.; Camarena, Phame M.

    2013-01-01

    Electronic communications technologies (ECTs) help college students and parents remain in contact. Because recent reports have emphasized a link between ECTs, helicopter parenting, and autonomy issues, this study focused on the significance of contact patterns for attachment and student adjustment. First-semester college students (199 female, 81…

  9. Postgraduate course at the Evolutionary Biology Centre, Uppsala University Digital Images and Scientific Illustrations, 2 HP (ECTS)

    E-print Network

    Uppsala Universitet

    and Scientific Illustrations, 2 HP (ECTS) Number of participants: 12 Aim: Graphic representations and images and producing graphic illustrations with Adobe Illustrator as software examples, respectively. The programs

  10. Students’ Factors Affecting Undergraduates’ Perceptions of their Teaching and Learning Process within ECTS Experience

    PubMed Central

    la Fuente, Jesús De; Cardelle-Elawar, María; Peralta, F. Javier; Sánchez, M. Dolores; Martínez-Vicente, José Manuel; Zapata, Lucía

    2010-01-01

    Introduction: In the present study, we investigated the potential factors that influenced the level of students satisfaction with the teaching–learning process (TLP), from the perspective of students participating in the European Credit Transfer System (ECTS) experience. Method: A total of 1490 students from the Universities of Almería and Granada (Spain) participated in an evaluation of their class discipline area. They completed the new revised protocol for evaluating the ECTS experience. Analyses of variance were carried out, taking the following factors as independent variables: student's grade average, year in school, study discipline, credit load in terms of ECTS credits assigned to a subject, the e-learning approach. Perception of the TLP was used as the dependent variable. Results: The data analyses showed variability of the degree of statistically significance among the factors that influenced students’ perceptions of the TLP. These factors included: Student's grade average (in favor of high performers), year in school (in favor of earlier years), ECTS load (in favor of subjects with a medium load of credits), and e-learning (in favor of its use). These research findings provided evidence to explore the delineation of a potential profile of factors that trigger a favorable perception of the TLP. Discussion and Conclusion: The present findings certainly have implications to deepen our understanding of the core beliefs, commitment, and the experience in shaping the implementation of the European Higher Education Area through the ECTS. PMID:21713171

  11. Ion-implantation doping of silicon carbide

    SciTech Connect

    Gardner, J.; Edwards, A.; Rao, M.V. [George Mason Univ., Fairfax, VA (United States); Papanicolaou, N.; Kelner, G. [Naval Research Lab., Washington, DC (United States); Holland, O.W. [Oak Ridge National Lab., TN (United States)

    1997-10-01

    Because of their commercial availability in bulk single crystal form, the 6H- and 4H- polytypes of SiC are gaining importance for high-power, high-temperature, and high-frequency device applications. Selective area doping is a crucial processing step in integrated circuit manufacturing. In Si technology, selective area doping is accomplished by thermal diffusion or ion-implantation. Because of the low diffusion coefficients of most impurities in SiC, ion implantation is indispensable in SiC device manufacturing. In this paper the authors present their results on donor, acceptor, and compensation implants in 6H-SiC.

  12. Cochlear implant placement: round window approach.

    PubMed

    Backous, Douglas D

    2014-01-01

    The indications for cochlear implantation continue to extend to patients with increased levels of residual hearing. Single-sided deafness and tinnitus are currently under various clinical trials as even further expansion of the application of cochlear implant device and programming technology is underway. This video details a round window and hearing preservation approach for cochlear implant placement, and incorporates the most recent advances in surgical technique. The video can be found here: http://youtu.be/bDqkbboXrU4 . PMID:24380531

  13. Expanded selection criteria in adult cochlear implantation.

    PubMed

    Arnoldner, Christoph; Lin, Vincent Y W

    2013-11-01

    Cochlear implantation has become the standard procedure for restoring substantial hearing in the profoundly deaf. The excellent performance of most of the CI recipients coupled with the rapid evolution of implant technology lead to a distinct expansion in selection criteria for CI. These changes in candidacy primarily include patients with (1) moderate preoperative speech recognition with hearing aids, (2) significant residual hearing, (3) single-sided deafness, and (4) geriatric patients. Many of these patients' conditions were regarded as a clear contraindication to CI only a few years ago. In this article an overview of the current and new aspects of candidacy for cochlear implantation is provided. PMID:24533755

  14. Toxoplasmosis Infection and Cognitive Deficit after Electroconvulsive Treatment (ECT), Is There a Connection?

    PubMed Central

    E. Berg, John

    2012-01-01

    Electroconvulsive treatment (ECT) has developed over 70 years to a modern, effective way of lifting depressive moods. Memory loss and visual acuity after electroconvulsive treatment is the only remaining relevant criticism of the treatment modality when considering the overall rate of remission from this treatment compared to all other treatment modalities. A depressive state impedes memory, and memory improves on several qualities of cognition after treatment. However, the comparison of a person’s memory ability from the months before depression started to the level after a course of ECT is never performed, for obvious reasons. Some infectious diseases are known to influence memory negatively through effects on the dopamine receptors. More specifically, former toxoplasmosis infection may be a factor. Preliminary data on titres of toxoplasma IgG may indicate a connection to the development of long-standing memory problems after ECT. PMID:24600630

  15. Networking issues in medical implant communications

    Microsoft Academic Search

    Bin Zhen; Huan-Bang Li; Ryuji Kohno

    2009-01-01

    IEEE 802.15 working group established a new task group, body area network (TG-BAN), to develop short range wireless technology in and around human body recently. This paper investigates networking issues in implant communications at 2.4 GHz frequency band. The object is better understanding of medical implant networks and how and where to start TG- BAN work. We applied IEEE 802.15.4b

  16. [Biomaterials in cochlear implants].

    PubMed

    Stöver, T; Lenarz, T

    2009-05-01

    Cochlear implants (CI) represent the "gold standard" for the treatment of congenitally deaf children and postlingually deafened adults. Thus, cochlear implantation is a success story of new bionic prosthesis development. Owing to routine application of cochlear implants in adults but also in very young children (below the age of one), high demands are placed on the implants. This is especially true for biocompatibility aspects of surface materials of implant parts which are in contact with the human body. In addition, there are various mechanical requirements which certain components of the implants must fulfil, such as flexibility of the electrode array and mechanical resistance of the implant housing. Due to the close contact of the implant to the middle ear mucosa and because the electrode array is positioned in the perilymphatic space via cochleostomy, there is a potential risk of bacterial transferral along the electrode array into the cochlea. Various requirements that have to be fulfilled by cochlear implants, such as biocompatibility, electrode micromechanics, and although a very high level of technical standards has been carried out there is still demand for the improvement of implants as well as of the materials used for manufacturing, ultimately leading to increased implant performance. General considerations of material aspects related to cochlear implants as well as potential future perspectives of implant development will be discussed. PMID:19353453

  17. Computer-Aided Implant Dentistry

    Microsoft Academic Search

    Wolfgang Birkfellner; Peter Solar; André Gahleitner; Klaus Huber; Franz Kainberger; Joachim Kettenbach; Peter Homolka; Markus Diemling; Georg Watzek; Helmar Bergmann

    \\u000a Computer-aided implant dentistry (CAID), the direct translation of preoperative prosthetic planning to the operating theater\\u000a by means of image guidance technologies, is a novel application of computer aided surgery (CAS). This work deals with the\\u000a application of a modular software system for computer-aided interventions to CAID. The system is based on AVW-2.5, a software\\u000a library dedicated to biomedical image processing,

  18. Physical understanding of cryogenic implant benefits for electrical junction stability

    SciTech Connect

    Adeni Khaja, Fareen; Colombeau, Benjamin; Thanigaivelan, Thirumal; Ramappa, Deepak; Henry, Todd [Applied Materials-Varian Semiconductor Equipment, 35 Dory Road, Gloucester, Massachusetts 01930 (United States)

    2012-03-12

    We investigate the effect of cryogenic temperature implants on electrical junction stability for ultra shallow junction applications for sub-32 nm technology nodes and beyond. A comprehensive study was conducted to gain physical understanding of the impact of cryogenic temperature implants on dopant-defect interactions. Carborane (C{sub 2}B{sub 10}H{sub 12}) molecule, a potential alternative to monomer boron was implanted in carbon preamorphized silicon substrates at cryogenic implant temperatures. Results indicate implants at cryogenic temperatures increase dopant activation with reduced diffusion, resulting in lower sheet resistance for a lower junction depth. Further, this study emphasizes the benefits of co-implants performed at cryogenic temperatures as alternative to traditional preamorphizing implants.

  19. The role of APOE-?4 and beta amyloid in the differential rate of recovery from ECT: a review

    PubMed Central

    Sutton, T A; Sohrabi, H R; Rainey-Smith, S R; Bird, S M; Weinborn, M; Martins, R N

    2015-01-01

    Individual biological differences may contribute to the variability of outcomes, including cognitive effects, observed following electroconvulsive treatment (ECT). A narrative review of the research literature on carriage of the apolipoprotein E ?4 allele (APOE-?4) and the protein biomarker beta amyloid (A?) with ECT cognitive outcome was undertaken. ECT induces repeated brain seizures and there is debate as to whether this causes brain injury and long-term cognitive disruption. The majority of ECT is administered to the elderly (over age 65 years) with drug-resistant depression. Depression in the elderly may be a symptom of the prodromal stage of Alzheimer's disease (AD). Carriage of the APOE-?4 allele and raised cerebral A? are consistently implicated in AD, but inconsistently implicated in brain injury (and related syndromes) recovery rates. A paucity of brain-related recovery, genetic and biomarker research in ECT responses in the elderly was found: three studies have examined the effect of APOE-?4 allele carriage on cognition in the depressed elderly receiving ECT, and two have examined A? changes after ECT, with contradictory findings. Cognitive changes in all studies of ECT effects were measured by a variety of psychological tests, making comparisons of such changes between studies problematic. Further, psychological test data-validity measures were not routinely administered, counter to current testing recommendations. The methodological issues of the currently available literature as well as the need for well-designed, hypothesis driven, longitudinal studies are discussed. PMID:25826114

  20. The role of APOE-?4 and beta amyloid in the differential rate of recovery from ECT: a review.

    PubMed

    Sutton, T A; Sohrabi, H R; Rainey-Smith, S R; Bird, S M; Weinborn, M; Martins, R N

    2015-01-01

    Individual biological differences may contribute to the variability of outcomes, including cognitive effects, observed following electroconvulsive treatment (ECT). A narrative review of the research literature on carriage of the apolipoprotein E ?4 allele (APOE-?4) and the protein biomarker beta amyloid (A?) with ECT cognitive outcome was undertaken. ECT induces repeated brain seizures and there is debate as to whether this causes brain injury and long-term cognitive disruption. The majority of ECT is administered to the elderly (over age 65 years) with drug-resistant depression. Depression in the elderly may be a symptom of the prodromal stage of Alzheimer's disease (AD). Carriage of the APOE-?4 allele and raised cerebral A? are consistently implicated in AD, but inconsistently implicated in brain injury (and related syndromes) recovery rates. A paucity of brain-related recovery, genetic and biomarker research in ECT responses in the elderly was found: three studies have examined the effect of APOE-?4 allele carriage on cognition in the depressed elderly receiving ECT, and two have examined A? changes after ECT, with contradictory findings. Cognitive changes in all studies of ECT effects were measured by a variety of psychological tests, making comparisons of such changes between studies problematic. Further, psychological test data-validity measures were not routinely administered, counter to current testing recommendations. The methodological issues of the currently available literature as well as the need for well-designed, hypothesis driven, longitudinal studies are discussed. PMID:25826114

  1. A no bleed implant

    Microsoft Academic Search

    Robert A. Ersek; Jose Alberto Navarro; Dora Zsofia Nemeth; George Sas

    1993-01-01

    Breast implants have evolved from the original saline-filled, smooth-surfaced silicone rubber bag to silicone gel-filled smooth-walled sacs to a combination of a silicone gel-filled bag within a saline-filled sac, and, most recently, a reversed, double-lumen implant with a saline bag inside of a gel-filled bag. Texture-surfaced implants were first used in 1970 when the standard silicone gelfilled implant was covered

  2. Cochlear Implants for Children.

    ERIC Educational Resources Information Center

    Hasenstab, M. Suzanne; Laughton, Joan

    1991-01-01

    The use of cochlear implants in children with profound bilateral hearing loss is discussed, focusing on how a cochlear implant works; steps in a cochlear implant program (evaluation, surgery, programing, and training); and rehabilitation procedures involved in auditory development and speech development. (JDD)

  3. Master's project in biology/immunology, 30 and 45 ECTS Exploring autoreactive B lymphocytes

    E-print Network

    Uppsala Universitet

    Master's project in biology/immunology, 30 and 45 ECTS Exploring autoreactive B lymphocytes Project of immunological techniques and equipment - Weekly lab meetings, journal clubs and seminars in immunology have a relevant background with completed courses in immunology and/or infectious biology. -Experience

  4. E ects of Contest Length and Noise on Reciprocal Altruism, Cooperation, and Payo s

    E-print Network

    Julstrom, Bryant A.

    E#11;ects of Contest Length and Noise on Reciprocal Altruism, Cooperation, and Payo#11;s altruism in such systems. A genetic algorithm whose popula- tion consists of strategies for the IPD was run and the num- ber of cooperative moves indicate the levels of reciprocal altruism and of cooperation, re

  5. The role of Atlantic ocean-atmosphere coupling in a ecting North Atlantic Oscillation variability

    E-print Network

    Huck, Thierry

    The role of Atlantic ocean-atmosphere coupling in a#11;ecting North Atlantic Oscillation Atlantic ocean as a heat reservoir 10 3.1 The reduced thermal damping argument . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 4 The North Atlantic Ocean as a heat carrier 28 4.1 NAO / ocean circulation interaction

  6. ccsd00001869, Multi-ion-species e ects on magnetosonic waves and energy

    E-print Network

    ccsd­00001869, version 1 ­ 22 Oct 2004 Multi-ion-species e#11;ects on magnetosonic waves and energy, wave damping, energy transport 1. Introduction The presence of multiple ion species introduces many Magnetosonic waves propagating perpendicular to an external magnetic #12;eld are studied with attention

  7. Top Ten Reasons a Graduate Student Should Apply to Be an ECT Foundation Intern

    ERIC Educational Resources Information Center

    York, Cindy S.

    2009-01-01

    In this article, the author encourages graduate students to apply for the ECT Foundation Internship. She presents a list of the top ten benefits the internship offers a graduate student's career: (1) It could change your life. It changed mine; (2) Networking; (3) Mentoring; (4) Leadership opportunities; (5) Behind the scenes pass; (6) Shadowing;…

  8. ccsd00000448 Swelling of phospholipid oating bilayers: the e ect of chain length

    E-print Network

    ccsd­00000448 (version 1) : 26 Jun 2003 Swelling of phospholipid oating bilayers: the e#11;ect of a homogeneous lipid bilayer, oating near an identical bilayer deposited on the hydrophilic surface of a silicon, n, varying from 16 to 20. The average and r.m.s. positions of the oating bilayer were determined

  9. Resubmitted to Icarus journal Yarkovsky e ect on small near{Earth asteroids

    E-print Network

    Milani, Andrea

    Resubmitted to Icarus journal Yarkovsky e#11;ect on small near{Earth asteroids: Mathematical demonstrated in relation to the transport of material from the main asteroid belt (both to explain the origin of near{Earth asteroids and some properties of meteorites) and also in relation to the aging processes

  10. Mathematical Existence of Crystal Growth with GibbsThomson Curvature E#ects 1

    E-print Network

    Wang, Lihe

    Mathematical Existence of Crystal Growth with Gibbs­Thomson Curvature E#ects 1 by Fred Almgren 2 one type of growth of a crystal as it freezes from a cold melt. The crystal freezes (melts) as rapidly. CHAPTER 2. Ingredients of our model of crystal growth. 2.1 The ambient space. 2.2 Crystals. 2.3 Heat

  11. Semi-parametric Nonlinear Mixed E ects Models and Their Applications

    E-print Network

    Wang, Yuedong

    Regression models (SEMOR) are often used to #12;t repeated measures data. They use a common function shared;ects models; Penalized likelihood; Repeated mea- sures; Self-modeling nonlinear regression; Smoothing spline; Smoothing spline ANOVA. 1 Introduction Repeated measures data arise in many areas

  12. Journal of Mathematical Chemistry 0 1999 ? ? 1 Chemical Clock Reactions: The E ect of Precursor

    E-print Network

    Billingham, John

    Journal of Mathematical Chemistry 0 1999 ? ? 1 Chemical Clock Reactions: The E ect of Precursor reaction is a chemical reaction which gives rise to a signi cant in- duction period during which one increases, for example cubic autocatal- #12;2 S. J. Preece et al Chemical Clock Reactions ysis: A + 2B ,! 3B

  13. No Shannon e#ect on probability distributions on Boolean functions induced by random expressions

    E-print Network

    Gittenberger, Bernhard

    that ``almost all'' Boolean functions have a complexity close to the maximal possible for the uniform the largest possible? What is the mean complexity of the Boolean functions? Note that the distributionNo Shannon e#ect on probability distributions on Boolean functions induced by random expressions

  14. Multiple Dimensions of Balance are Adversely A ected in Older Adults with Fibromyalgia

    E-print Network

    de Lijser, Peter

    Multiple Dimensions of Balance are Adversely A ected in Older Adults with Fibromyalgia Table 1 erent dimensions of balance and mobility in younger adults [2]. The goal of this study was to address this important question with a group of older adults with FM. The Fullerton Advanced Balance (FAB) Scale

  15. Stark E ect of Interactive Electron-hole pairs in Spherical Semiconductor Quantum Dots

    E-print Network

    Recanati, Catherine

    for an increasing range of future applications: e.g. as a semiconductor laser [1] or as single-photon sources [2 the motion of one to a hundred embedded elementary charge carriers, which may be conduction band electrons size e#11;ects (QSE) showed up through optical properties of spherical semiconductor micro-crystals

  16. Destructive E ect Analysis And Finite Di erencing For Strict Functional Languages

    E-print Network

    Mohri, Mehryar

    Destructive E#11;ect Analysis And Finite Di#11;erencing For Strict Functional Languages by Chung for their unconditional support over the years. vi #12; Preface Destructive update optimization is critical to the performance of functional pro- grams. Pure functional languages do not allow mutations, destructive updates

  17. Caricatural E ects in Automated Face Perception R. Brunelli

    E-print Network

    Poggio, Tomaso

    Massachusetts Institute of Technology Cambridge, Massachusetts 02139, USA Abstract|This paper analyzes, extracted automatically from digitized pictures of frontal views of people without facial hair. The Hyper, emotions. In the current paper we address the tasks of gender classi cation and recognition. The work

  18. Miniaturized neural interfaces and implants

    NASA Astrophysics Data System (ADS)

    Stieglitz, Thomas; Boretius, Tim; Ordonez, Juan; Hassler, Christina; Henle, Christian; Meier, Wolfgang; Plachta, Dennis T. T.; Schuettler, Martin

    2012-03-01

    Neural prostheses are technical systems that interface nerves to treat the symptoms of neurological diseases and to restore sensory of motor functions of the body. Success stories have been written with the cochlear implant to restore hearing, with spinal cord stimulators to treat chronic pain as well as urge incontinence, and with deep brain stimulators in patients suffering from Parkinson's disease. Highly complex neural implants for novel medical applications can be miniaturized either by means of precision mechanics technologies using known and established materials for electrodes, cables, and hermetic packages or by applying microsystems technologies. Examples for both approaches will be introduced and discussed. Electrode arrays for recording of electrocorticograms during presurgical epilepsy diagnosis have been manufactured using approved materials and a marking laser to achieve an integration density that is adequate in the context of brain machine interfaces, e.g. on the motor cortex. Microtechnologies have to be used for further miniaturization to develop polymer-based flexible and light weighted electrode arrays to interface the peripheral and central nervous system. Polyimide as substrate and insulation material will be discussed as well as several application examples for nerve interfaces like cuffs, filament like electrodes and large arrays for subdural implantation.

  19. Annexin V-induced rat Leydig cell proliferation involves Ect2 via RhoA/ROCK signaling pathway.

    PubMed

    Jing, Jun; Chen, Li; Fu, Hai-Yan; Fan, Kai; Yao, Qi; Ge, Yi-Feng; Lu, Jin-Chun; Yao, Bing

    2015-01-01

    This study investigated the effect of annexin V on the proliferation of primary rat Leydig cells and the potential mechanism. Our results showed that annexin V promoted rat Leydig cell proliferation and cell cycle progression in a dose- and time-dependent manner. Increased level of annexin V also enhanced Ect2 protein expression. However, siRNA knockdown of Ect2 attenuated annexin V-induced proliferation of rat Leydig cells. Taken together, these data suggest that increased level of annexin V induced rat Leydig cell proliferation and cell cycle progression via Ect2. Since RhoA activity was increased following Ect2 activation, we further investigated whether Ect2 was involved in annexin V-induced proliferation via the RhoA/ROCK pathway, and the results showed that annexin V increased RhoA activity too, and this effect was abolished by the knockdown of Ect2. Moreover, inhibition of the RhoA/ROCK pathway by a ROCK inhibitor, Y27632, also attenuated annexin V-induced proliferation and cell cycle progression. We thus conclude that Ect2 is involved in annexin V-induced rat Leydig cell proliferation through the RhoA/ROCK pathway. PMID:25807302

  20. [The implantable automatic defibrillator].

    PubMed

    Chauvin, M; Jesel, L; Douchet-Krebs, M P

    2004-11-01

    Technical advances in the design of implantable automatic defibrillators have been constant since the introduction of these devices in the mid 80s. The most obvious advance is the miniaturisation of the devices from which all components have benefited. The capacity of the batteries has improved inversely proportionally to their size, even if the longevity has not always lived up to expectations. The volumic energy of the condensers has improved and their technology also, and their size has decreased. Condensers are still usually made by the electrolytic/aluminium method but tantalum technology is bound to become more generalised because it presents so many advantages. Above all, the circuitry has benefited from the progress of micro-electronics, associating miniaturisation with an increase in more and more complex functions...but requiring more electrical current. Of these functions, algorithms to detect arrhythmias has reduced the number of inappropriate shocks but do not yet have excellent specificity either in single or in dual chamber sensing. Defibrillators incorporating a multisite anti-bradycardiac function are more and more popular because of the close relationship between cardiac failure and sudden death. PMID:15609913

  1. Finite volume analysis of temperature effects induced by active MRI implants: 2. Defects on active MRI implants causing hot spots

    Microsoft Academic Search

    Martin HJ Busch; Wolfgang Vollmann; Dietrich HW Grönemeyer

    2006-01-01

    BACKGROUND: Active magnetic resonance imaging implants, for example stents, stent grafts or vena cava filters, are constructed as wireless inductively coupled transmit and receive coils. They are built as a resonator tuned to the Larmor frequency of a magnetic resonance system. The resonator can be added to or incorporated within the implant. This technology can counteract the shielding caused by

  2. Science Highlights from the RBSP-ECT Particle Instrument Suite on NASA's Van Allen Probes Mission

    NASA Astrophysics Data System (ADS)

    Spence, Harlan

    2014-05-01

    The NASA Van Allen Probes mission includes an instrument suite known as the Radiation Belt Storm Probes (RBSP) - Energetic Particle, Composition, and Thermal Plasma (ECT) suite. RBSP-ECT contains a well-proven complement of particle instruments to ensure the highest quality measurements ever made in the radiation belts and the inner magnetosphere. The coordinated RBSP-ECT particle measurements, analyzed in combination with fields and waves observations and state of-the-art theory and modeling, provide new understanding on the acceleration, global distribution, and variability of radiation belt electrons and ions, key science objectives of NASA's Living With a Star program and the Van Allen Probes mission. The RBSP-ECT suite consists of three highly-coordinated instruments: the Helium Oxygen Proton Electron (HOPE) spectrometer, the Magnetic Electron Ion Spectrometer (MagEIS), and the Relativistic Electron Proton Telescope (REPT). Collectively these three instrument types cover comprehensively the full electron and ion spectra from one eV to 10's of MeV with sufficient energy resolution, pitch angle coverage and resolution, and with composition measurements in the critical energy range up to 50 keV and also from a few to 50 MeV/nucleon. All three instruments are based on measurement techniques proven in the radiation belts, then optimized to provide unambiguous separation of ions and electrons and clean energy responses even in the presence of extreme penetrating background environments. In this presentation, we summarize overall ECT science goals and then show scientific results derived from the ECT suite on the dual Van Allen Probes spacecraft to date. Mission operations began only in late October 2012, and we have now achieved significant results. Results presented here will include substantial progress toward resolving primary Van Allen Probes science targets, such as: the relative role of localized acceleration versus transport-generated particle acceleration; the role of plasma electron temperature anisotropies, whistler waves, and radiation belt electron variability; global characteristics of outer zone electron drift loss to the magnetopause; the role of storms, substorms, and ion composition in radiation belt dynamics, both in terms of sources and sinks; new physical perspectives on inner zone and slot protons and electrons; and, how plasmasphere properties control or influence radiation belt behavior.

  3. Bernas ion source modifications for platinum and aluminum ion implantation (abstract)

    Microsoft Academic Search

    C. Medulla; M. Raspagliesi

    1998-01-01

    Technology has a continuous developmental push toward the semiconductor's fabrication to find new solutions to improve its own production. Hence the request to implant platinum and aluminum using commercial ion implanters in scanning tunneling microscopy was born. Starting with a standard Bernas source, we modified the conventional operating mode, as follows, to adapt the requested ion implantation process on our

  4. Music Perception with Cochlear Implants: A Review

    PubMed Central

    McDermott, Hugh J.

    2004-01-01

    The acceptance of cochlear implantation as an effective and safe treatment for deafness has increased steadily over the past quarter century. The earliest devices were the first implanted prostheses found to be successful in compensating partially for lost sensory function by direct electrical stimulation of nerves. Initially, the main intention was to provide limited auditory sensations to people with profound or total sensorineural hearing impairment in both ears. Although the first cochlear implants aimed to provide patients with little more than awareness of environmental sounds and some cues to assist visual speech-reading, the technology has advanced rapidly. Currently, most people with modern cochlear implant systems can understand speech using the device alone, at least in favorable listening conditions. In recent years, an increasing research effort has been directed towards implant users’ perception of nonspeech sounds, especially music. This paper reviews that research, discusses the published experimental results in terms of both psychophysical observations and device function, and concludes with some practical suggestions about how perception of music might be enhanced for implant recipients in the future. The most significant findings of past research are: (1) On average, implant users perceive rhythm about as well as listeners with normal hearing; (2) Even with technically sophisticated multiple-channel sound processors, recognition of melodies, especially without rhythmic or verbal cues, is poor, with performance at little better than chance levels for many implant users; (3) Perception of timbre, which is usually evaluated by experimental procedures that require subjects to identify musical instrument sounds, is generally unsatisfactory; (4) Implant users tend to rate the quality of musical sounds as less pleasant than listeners with normal hearing; (5) Auditory training programs that have been devised specifically to provide implant users with structured musical listening experience may improve the subjective acceptability of music that is heard through a prosthesis; (6) Pitch perception might be improved by designing innovative sound processors that use both temporal and spatial patterns of electric stimulation more effectively and precisely to overcome the inherent limitations of signal coding in existing implant systems; (7) For the growing population of implant recipients who have usable acoustic hearing, at least for low-frequency sounds, perception of music is likely to be much better with combined acoustic and electric stimulation than is typical for deaf people who rely solely on the hearing provided by their prostheses. PMID:15497033

  5. Music perception with cochlear implants: a review.

    PubMed

    McDermott, Hugh J

    2004-01-01

    The acceptance of cochlear implantation as an effective and safe treatment for deafness has increased steadily over the past quarter century. The earliest devices were the first implanted prostheses found to be successful in compensating partially for lost sensory function by direct electrical stimulation of nerves. Initially, the main intention was to provide limited auditory sensations to people with profound or total sensorineural hearing impairment in both ears. Although the first cochlear implants aimed to provide patients with little more than awareness of environmental sounds and some cues to assist visual speech-reading, the technology has advanced rapidly. Currently, most people with modern cochlear implant systems can understand speech using the device alone, at least in favorable listening conditions. In recent years, an increasing research effort has been directed towards implant users' perception of nonspeech sounds, especially music. This paper reviews that research, discusses the published experimental results in terms of both psychophysical observations and device function, and concludes with some practical suggestions about how perception of music might be enhanced for implant recipients in the future. The most significant findings of past research are: (1) On average, implant users perceive rhythm about as well as listeners with normal hearing; (2) Even with technically sophisticated multiple-channel sound processors, recognition of melodies, especially without rhythmic or verbal cues, is poor, with performance at little better than chance levels for many implant users; (3) Perception of timbre, which is usually evaluated by experimental procedures that require subjects to identify musical instrument sounds, is generally unsatisfactory; (4) Implant users tend to rate the quality of musical sounds as less pleasant than listeners with normal hearing; (5) Auditory training programs that have been devised specifically to provide implant users with structured musical listening experience may improve the subjective acceptability of music that is heard through a prosthesis; (6) Pitch perception might be improved by designing innovative sound processors that use both temporal and spatial patterns of electric stimulation more effectively and precisely to overcome the inherent limitations of signal coding in existing implant systems; (7) For the growing population of implant recipients who have usable acoustic hearing, at least for low-frequency sounds, perception of music is likely to be much better with combined acoustic and electric stimulation than is typical for deaf people who rely solely on the hearing provided by their prostheses. PMID:15497033

  6. Programming, Care, and Troubleshooting of Cochlear Implants for Children.

    ERIC Educational Resources Information Center

    Hedley-Williams, Andrea J.; Sladen, Douglas P.; Tharpe, Anne Marie

    2003-01-01

    This article provides an overview of current cochlear implant technology, programming strategies, troubleshooting, and care techniques. It considers: device components, initial stimulation, speech coding strategies, use and care, troubleshooting, and the classroom environment. (Contains references.) (DB)

  7. D Rf-Ect Simulations of Isi of U-Bend SG Tubes in Fbr

    NASA Astrophysics Data System (ADS)

    Mihalache, Ovidiu; Yamaguchi, Toshihiko; Ueda, Masashi; Tsukimori, Kazuyuki

    2010-02-01

    The paper focus on 3-dimensional finite element simulations of the steam generator inspection using remote field eddy current testing (RF-ECT) in order to asses the performance of the in-service inspection in SG tubes. It is evaluated the influences of the SG tubes U-bend curvature on the eddy current sensor signal by taking into account a 3D model in which also multiple SG tubes are located close to each other, as in the nuclear reactor.

  8. English Bachelor Modules Dep. EI 09/14 Modul ID Modulbezeichnung Sem. ECTS

    E-print Network

    Kuehnlenz, Kolja

    English Bachelor Modules Dep. EI 09/14 Modul ID Modulbezeichnung Sem. ECTS Lehrform V/Ü/P SWS Prüfungsart Spra- che EI0679 Basic Laboratory Course on Telecommunications WS/SS 5 0/0/4 4 7x s, 30 min (je 1/7) E EI0554 Blockpraktikum C++ WS/SS 6 2/0/4 6 s, 60 min (60%) + m (40%) + l (SL) D/E EI0607

  9. Radiation hard position-sensitive cryogenic silicon detectors: the Lazarus e!ect

    Microsoft Academic Search

    V. G. Palmieri; M. C. Abreu; W. H. Bell; P. Berglund; E. Borchi; K. Borer; M. Bruzzi; S. Buontempo; L. Casagrande; S. Chapuy; V. Cindro; N. D'Ambrosio; S. Devine; B. Dezillie; Z. Dimcovski; V. Eremin; A. Esposito; E. Grigoriev; F. Hauler; E. Heijne; S. Heising; S. Janos; L. Jungermann; I. Konorov; Z. Li; M. Mikuz; T. O. Niinikoski; V. O'Shea; S. Pagano; S. Paul; S. Pirollo; K. Pretzl; P. Rato; G. Ruggiero; K. Smith; P. Sonderegger; P. Sousa; E. Verbitskaya; S. Watts; M. Zavrtanik

    2000-01-01

    The discovery of the so-called Lazarus e!ect, namely the recovery of the charge collection e$ciency (CCE) of irradiated silicon detectors by means of cryogenic cooling has entailed an increasing interest in the behavior of silicon detectors at cryogenic temperatures. We have measured the CCE of a silicon p}i}n diode detector previously irradiated with an equivalent #uence of 1)1015 n\\/cm2 neutrons

  10. How robust is the evidence on the e ects of college quality? Evidence from matching

    Microsoft Academic Search

    Dan A. Blacka; A. Smith

    2004-01-01

    We estimate the e ects of college quality using propensity score matching methods and the National Longitudinal Survey of Youth 1979 cohort. Matching allows us to relax the linear functional form assumption implicit in regression-based estimates. We also examine the support problem by determining whether there are individuals attending low-quality colleges similar to those attending high-quality colleges, and 4nd that

  11. Ketofol-Dexmedetomidine combination in ECT: A punch for depression and agitation

    PubMed Central

    Shams, Tarek; El-Masry, Ragaa

    2014-01-01

    Background and Aims: The choice of anaesthetic agent for electroconvulsive therapy (ECT) depends on seizure duration, haemodynamic, and recovery parameters. The aim of the study was to assess the effects of ketamine-propofol induction with dexmedetomidine preadministration (ketofol-dex group) and without its preadministration (ketofol group) on haemodynamics, depression, seizure duration, recovery characteristics, and agitation following ECT in patients with depression. Methods: 40 patients aged 18-60 years were scheduled for ECT for treatment of depression. Dexmedetomidine (0.5 ?g/kg) diluted to a volume of 10 ml with 0.9% saline or 10 ml 0.9% saline were infused intravenously over 10 minutes before induction of anaesthesia with ketamine and propofol (ketofol). Statistical analysis was carried out using the Statistical Software for the Social Sciences (SPSS) package. Results: Motor seizure duration in ketofol group was significantly less compared to ketofol-dex group (35.8 ± 6.6s versus 38.9 ± 4.9s). Total ketofol used was significantly less in ketofol-dex group compared to ketofol group (78.5 ± 10.8mg versus 90 ± 13.2mg). The number of patients with agitation score >2 was significantly lower in ketofol-dex group (1.4%) compared to ketofol group (8.6%). There was significant decrease (P = 0.000) in mean arterial pressure (MAP) and heart rate (HR) in ketofol-dex group compared to ketofol group at 20, 30, and 40 minutes for MAP and at 10, 20, 30, and 40 minutes for HR. Conclusions: Ketofol-dex mixture in ECT is associated with longer mean seizure duration, effective anti-depression, less incidence of agitation, more patient satisfaction, and acceptable decreases in blood pressure and HR when compared to ketofol alone. PMID:25024469

  12. An Improved Coded-Aperture System for Emission Computed Tomography (ECT)

    Microsoft Academic Search

    LeRoy R. Price

    1979-01-01

    The performance of an ECT system using an annular coded aperture and concentric annular detector has been studied by computer simulation. To Insure that the simulations are realistic, all appropriate geometrical factors (e.g. inverse-square attenuation) and tissue photon-interaction properties (both multiple Compton scattering and photoelectric effect) were Included. Also included was a 1% energy uncertainty to emulate solid-state detectors. The

  13. Who Is an Implant Candidate?

    MedlinePLUS

    ... interested in replacing a missing tooth or teeth, dental implants may be an option for you. Most people ... restorative dentist will make the crowns, bridges or dentures that the implant or implants will support. Your ...

  14. Postgraduate course at the Evolutionary Biology Centre, Uppsala University Digital Images and Scientific Illustrations, 2 HP (ECTS)

    E-print Network

    Uppsala Universitet

    and Scientific Illustrations, 2 HP (ECTS) Number of participants: 12 Aim: Graphic representations and images illustrations with Photoshop and Illustrator as a software examples. The software will be demonstrated

  15. Improved medical implants comes from nanostructuring

    E-print Network

    remarkably improves other metal properties, including strength, cyclic load resistance, corrosion resistance for those with medical implants improves as science and medicine unite once more Metals have provided. A more recent innovation in metals technology--nanostructuring--heralds a new era for metals in medical

  16. [Evaluation of asymmetric implants in breast augmentation surgery].

    PubMed

    Fitoussi, A D; Couturaud, B

    2005-10-01

    Since more than 30 years, the quality of breast implants has continued to evolve in order to improve the aesthetic results of prosthetic augmentation. Shapes and materials of these implants have also evolved to obtain stronger and more reliable prostheses almost similar to the natural breast. Therefore it can be considered that the use of asymmetric implants is the last step in implant technology before using made to measure implants. Asymmetric implants allow obtaining different contours in harmony to the different breast shapes capable to reproduce faithfully, in all dimensions, the anatomy of the female breast, including the differences between each side which maximise the naturalness of the result. Such implants have an axis directed towards the exterior and lower part of the chest wall, are wider than high with a thinner part on their inner edge and a concave rear side moulding the curves of the chest wall. In our own experience, we placed between 2002 and 2004, asymmetric implants in 100 patients. Such implants were easy to place and no secondary rotation was observed. The control of secondary displacements even in case of prosthesis change seems to be linked to their concave rear side, roughness and asymmetry. When analysing retrospectively the medical records, no distinctive features were observed when compared to symmetric classic implants in easiness in the surgical procedure or in complications except a slightly higher rate of seroma formation. However asymmetric implants are less appropriate in case of major breast ptosis, patients being unsatisfied by the "too natural" breast shape. Moreover a high risk of secondary rotation seems to be real in such cases. In summary, for all these reasons, asymmetric implants, are gradually considered to be a first-rank choice for implants in breast augmentation cosmetic surgery. PMID:16198044

  17. Micro- and nano-fabricated implantable drug-delivery systems

    PubMed Central

    Meng, Ellis; Hoang, Tuan

    2013-01-01

    Implantable drug-delivery systems provide new means for achieving therapeutic drug concentrations over entire treatment durations in order to optimize drug action. This article focuses on new drug administration modalities achieved using implantable drug-delivery systems that are enabled by micro- and nano-fabrication technologies, and microfluidics. Recent advances in drug administration technologies are discussed and remaining challenges are highlighted. PMID:23323562

  18. ECT Evaluation by an Error Measurement System According to IEC 60044-8 and 61850-9-2

    Microsoft Academic Search

    Tatsuji Yamada; Saytaro Kon; Naoki Hashimoto; Tatsushi Yamaguchi; Kenichi Yazawa; Reishi Kondo; Kiyoshi Kurosawa

    2012-01-01

    A high-accuracy error measurement system for calibration of digital-output equipped electronic current transformers (ECTs) is described. The system has been developed in conformity with the requirements for digital information networks in IEC 61850-9-2 and for accuracy class and error measurement procedures in IEC 60044-8. The system has also been designed to achieve simultaneous and synchronous samplings between an ECT\\/MU and

  19. Rapid Response of Long-Standing, Treatment-Resistant Non-Catatonic Mutism in Paranoid Schizophrenia with Single ECT session

    PubMed Central

    Dar, Mansoor Ahmad; Rather, Yasir Hassan; Shah, Majid Shafi; Wani, Rayees Ahmad; Hussain, Arshad

    2014-01-01

    Context: Mutism is a common manifestation of catatonia, but mutism due to other forms of psychopathology and neurological disorders have also been described. Although not common, long-standing mutism has also been a feature of non-catatonic schizophrenia and traditionally responds less to conventional therapies. Case Report: We describe a rare case of paranoid schizophrenia presenting with continuous mutism for about 4 years. This 26-year-old male had symptoms of schizophrenia without catatonia. After failed trial of adequate pharmacotherapy and psychological intervention and considering his level of dysfunction, he was started on electroconvulsive therapy (ECT). To our surprise, he improved with a single session of ECT while he was on concurrent pharmacotherapy. We also discuss the possible explanation for this rapid effect of ECT in such clinical presentation. To our knowledge, this is the first case of non-catatonic mutism of schizophrenia of this long duration responding so promptly to ECT, although there are other reports as well in literature, but multiple ECT sessions were applied in those cases. Conclusion: Non-catatonic mutism is perhaps presenting as a cultural variant in this part of the world and whenever encountered, ECT should be an option. Further research should be carried out to validate this idea. PMID:25535609

  20. Bioceramics for implant coatings

    Microsoft Academic Search

    Allison A Campbell

    2003-01-01

    During the past century, synthetic materials and devices have been developed to the point at which they can be used successfully to replace and\\/or restore function to diseased or damaged tissues. In the field of orthopedics, the use of metal implants has significantly improved the quality of life for countless individuals. Critical factors for implant success include proper design, material

  1. Chemotherapeutics in implant dentistry.

    PubMed

    Zablotsky, M H

    1993-01-01

    Adjunctive treatment with various chemotherapeutic regimens in implant dentistry are reviewed along with the indications for specific approaches. The use of systemic antibiotics, topical antimicrobials, and various mechanical modalities are discussed in relation to patient maintenance and the repair of ailing implants. PMID:8358373

  2. Batteryless implanted echosonometer

    NASA Technical Reports Server (NTRS)

    Kojima, G. K.

    1977-01-01

    Miniature ultrasonic echosonometer implanted within laboratory animals obtains energy from RF power oscillator that is electronically transduced via induction loop to power receiving loop located just under animal's skin. Method of powering device offers significant advantages over those in which battery is part of implanted package.

  3. Annealing of PEEK, PET and PI implanted with Co ions at high fluencies

    NASA Astrophysics Data System (ADS)

    Mackova, A.; Malinsky, P.; Miksova, R.; Pupikova, H.; Khaibullin, R. I.; Valeev, V. F.; Svorcik, V.; Slepicka, P.

    2013-07-01

    The properties of implanted polymers strongly depend on the implantation ion fluence and on the properties of the implanted atoms. The stability of synthesized nano-structures during further technological steps like annealing is of importance for their possible applications. Polyimide (PI), polyetheretherketone (PEEK), and polyethyleneterephtalate (PET) were implanted with 40 keV Co+ ions at room temperature at fluences ranging from 0.2 × 1016 cm-2 to 1.0 × 1017 cm-2 and annealed at a temperature of 200 °C. The implanted depth profiles of as-implanted and annealed samples, determined by the RBS method, were compared with the results of SRIM 2012 simulations. The structural and compositional changes of the implanted and subsequently annealed polymers were characterized by RBS and UV-vis spectroscopy. The surface morphology of as-implanted and annealed samples was examined by the AFM method and their electrical properties by sheet resistance measurement.

  4. Inexpensive cochlear implant device.

    PubMed

    Kanchanarak, C; Siriratwatanakul, N; Boonyanukul, S; Saeng-in, A; Krairojananan, T

    1991-12-01

    We have developed a cochlear implant (CI) device modified from the House/3M cochlear implant device. The cost of raw materials was about $25. We used a new and simple technique for coating the implanted coil. We modified the circuit and removed the amplitude-modulated circuit. With this modification, the device uses less electricity and fewer transistors. There are slightly more than 3,000 patients using CI devices all over the world. Millions of profoundly deaf patients are poor and cannot afford the CI device that is now commercially available. Any university with well-trained otolaryngologists and physicists or electrical engineers can perform this technique. PMID:1746846

  5. DEALING WITH DENTAL IMPLANT FAILURES

    PubMed Central

    Levin, Liran

    2008-01-01

    An implant-supported restoration offers a predictable treatment for tooth replacement. Reported success rates for dental implants are high. Nevertheless, failures that mandate immediate implant removal do occur. The consequences of implant removal jeopardize the clinician's efforts to accomplish satisfactory function and esthetics. For the patient, this usually involves further cost and additional procedures. The aim of this paper is to describe different methods and treatment modalities to deal with dental implant failure. The main topics for discussion include identifying the failing implant, implants replacing failed implants at the exact site, and the use of other restorative options. When an implant fails, a tailor made treatment plan should be provided to each patient according to all relevant variables. Patients should be informed regarding all possible treatment modalities following implant failure and give their consent to the most appropriate treatment option for them. PMID:19089213

  6. Cost effectiveness of the multichannel cochlear implant.

    PubMed

    Wyatt, J R; Niparko, J K; Rothman, M L; deLissovoy, G

    1995-01-01

    Although most third-party payors presently fund cochlear implantation, some do not, and many cite the current lack of cost-effectiveness data as a major concern. Cost-utility analysis is a widely used method of medical technology assessment that permits cost-effectiveness comparisons between medical interventions by determining the cost per quality-adjusted life-year (QALY) they provide. The cost per QALY for the cochlear implant was determined using clinical cost data and a health-utility outcome model based on the established communication gains attained with the device. Cochlear implantation costs approximately $15,600 per QALY provided. Sensitivity analysis, a technique that systematically varies the assumptions underlying the calculations, favorably with other medical interventions, such as coronary artery bypass grafting ($10,431) for three-vessel disease, $64,033 for single-vessel disease), the implantable defibrillator ($29,200), and cardiac transplantation ($38,970). This analysis indicates that the cochlear implant lies well within the cost-effectiveness range currently accepted by the American medical system. PMID:8579178

  7. Ion implantation at elevated temperatures

    SciTech Connect

    Lam, N.Q.; Leaf, G.K.

    1985-11-01

    A kinetic model has been developed to investigate the synergistic effects of radiation-enhanced diffusion, radiation-induced segregation and preferential sputtering on the spatial redistribution of implanted solutes during implantation at elevated temperatures. Sample calculations were performed for Al and Si ions implanted into Ni. With the present model, the influence of various implantation parameters on the evolution of implant concentration profiles could be examined in detail.

  8. Implant treatment planning: endodontic considerations.

    PubMed

    Simonian, Krikor; Frydman, Alon; Verdugo, Fernando; Roges, Rafael; Kar, Kian

    2014-12-01

    Implants are a predictable and effective method for replacing missing teeth. Some clinicians have advocated extraction and replacement of compromised but treatable teeth on the assumption that implants will outperform endodontically and/or periodontally treated teeth. However, evidence shows that conventional therapy is as effective as implant treatment. With data on implants developing complications long term and a lack of predictable treatment for peri-implantitis, retaining and restoring the natural dentition should be the first choice when possible. PMID:25928961

  9. Corrosion of surgical implants.

    PubMed

    Traisnel, M; le Maguer, D; Hildebrand, H F; Iost, A

    1990-01-01

    Corrosion on orthopaedic implants has been studied. Twelve intramedullary nails and twelve osteosynthesis plates were implanted up to eight and thirteen years, respectively. Analysis of biological fluids from all patients was carried out and revealed high concentrations of nickel and chromium that correlated to the implantation time. All implants were corroded by both crevice and intergranular corrosion. Intergranular corrosion is related to mechanical and heating treatments. Crevice-like corrosion is probably enhanced by sulphur present in amino-acids. Electronic probe analysis shows the reaction study between both sulphur and nickel and sulphur and chromium. These results are compared to the metal distribution in body fluids. After a certain incubation time the corrosion accelerates as is characteristic for crevice-like corrosion processes. Studies of the distribution rate of two Ni-Fe-Cr dental alloys in a cell culture system give similar results: metal-ion release increases with the exposure time. PMID:10147509

  10. Cochlear implantation update.

    PubMed

    Francis, Howard W; Niparko, John K

    2003-04-01

    Cochlear implantation is recognized as a valuable intervention with important implications for the acquisition of speech perception and verbal language in children with severe to profound hearing impairment. Auditory rehabilitation, language intervention, and close coordination between parents, schools, and the implant center are necessary to maximize efficacy. Early identification of hearing loss, early hearing aid use and language intervention, and cochlear implantation by 2 years of age are positive predictors for language acquisition that can approach the levels of normal-hearing children. There are early indications that increased access to mainstream education and gains in quality of life are long-term benefits that render cochlear implantation a cost-effective intervention. PMID:12809327

  11. [Osteosynthesis using absorbable implants].

    PubMed

    Arva, G; Fröhlich, P

    1994-01-01

    Authors report on one case of malleolar synthesis with the use of biodegradable implants. The advantages of the resorbing osteosynthesis materials and the possible complications are described. PMID:8162144

  12. Negative-ion implantation

    SciTech Connect

    Ishikawa, Junzo [Kyoto Univ., Yoshida, Kyoto (Japan). Dept. of Electronics

    1995-12-31

    Negative-ion implantation is a promising technique for forthcoming ULSI (more than 256 M bits) fabrication and TFT (for color LCD) fabrication, since the surface charging voltage of insulated electrodes or insulators implanted by negative ions is found to saturate within so few as several volts, no breakdown of insulators would be expected without a charge neutralizer in these fabrication processes. Scatter-less negative-ion implantation into powders is also possible. For this purpose an rf-plasma-sputter type heavy negative-ion source was developed, which can deliver several milliamperes of various kinds of negative ion currents such as boron, phosphor, silicon, carbon, copper, oxygen, etc. A medium current negative-ion implanter with a small version of this type of ion source has been developed.

  13. Implant-Supported Bridge

    MedlinePLUS

    ... made by the dental lab. Porcelain-fused-to-metal bridge The restoration (the part that looks like ... porcelain attached and fused to a framework of metal. The Implant Process The time it takes to ...

  14. Histopathology of ossicular implants.

    PubMed

    Merchant, S N; Nadol, J B

    1994-08-01

    Ossicular and cortical bone grafts maintain their morphologic structure for long periods of time and show varying amounts of replacement of nonviable bone by new bone through a slow process of creeping substitution. Cartilage grafts develop chondromalacia, lose stiffness, and tend to be resorbed over time. Plastipore prostheses elicit foreign body giant cell responses with microscopic biodegradation of the implants. There is a great need for the study of well-documented human temporal bone cases with in situ ossicular implants. PMID:7984378

  15. Effects of MPII-implanted titanium on the electrochromic properties of tungsten trioxide

    NASA Astrophysics Data System (ADS)

    Weng, Ko-Wei; Han, Sheng; Chen, Ya-Chi; Chuang, Han-Chun

    2008-04-01

    There are great interests in electrochromic (EC) technology for smart windows and displays over the last decade. The substrate, a conductive glass being coated indium tin oxide (ITO) thin films, deposited tungsten trioxide (WO 3) using radio-frequency (RF) sputtering and implanted Ti by a metal-plasma ion implantation (MPII) in this study. The optical density (when the implanted dose is less than 2 × 10 15 ions/cm 2) is approximately 1.6 times the unimplanted Ti. At low implanted dose +6 valence tungsten ions improve optical density. At high implanted dose, low-valence tungsten ions reduce the optical density.

  16. Biocompatible implant surface treatments.

    PubMed

    Pattanaik, Bikash; Pawar, Sudhir; Pattanaik, Seema

    2012-01-01

    Surface plays a crucial role in biological interactions. Surface treatments have been applied to metallic biomaterials in order to improve their wear properties, corrosion resistance, and biocompatibility. A systematic review was performed on studies investigating the effects of implant surface treatments on biocompatibility. We searched the literature using PubMed, electronic databases from 1990 to 2009. Key words such as implant surface topography, surface roughness, surface treatment, surface characteristics, and surface coatings were used. The search was restricted to English language articles published from 1990 to December 2009. Additionally, a manual search in the major dental implant journals was performed. When considering studies, clinical studies were preferred followed by histological human studies, animal studies, and in vitro studies. A total of 115 articles were selected after elimination: clinical studies, 24; human histomorphometric studies, 11; animal histomorphometric studies, 46; in vitro studies, 34. The following observations were made in this review: · The focus has shifted from surface roughness to surface chemistry and a combination of chemical manipulations on the porous structure. More investigations are done regarding surface coatings. · Bone response to almost all the surface treatments was favorable. · Future trend is focused on the development of osteogenic implant surfaces. Limitation of this study is that we tried to give a broader overview related to implant surface treatments. It does not give any conclusion regarding the best biocompatible implant surface treatment investigated till date. Unfortunately, the eventually selected studies were too heterogeneous for inference of data. PMID:23059581

  17. Microtelemetry techniques for implantable smart sensors

    NASA Astrophysics Data System (ADS)

    Troyk, Philip R.; Schwan, M. A.; DeMichele, G. A.; Loeb, Gerald E.; Schulman, Joe; Strojnik, P.

    1996-05-01

    The advent of the emerging field of smart sensors suggests new applications for implantable microelectronic devices in neural prostheses. Optimal use of miniature and subminiature (thin- film) electronic sensors in implanted systems will depend upon the nature of the power and communication link to the sensor. Microtelemetry technology is under current development to meet this need. Microtelemetry techniques can be used to provide operating power and bi- directional communication for a microimplant through a common, wireless, magnetic link. Owing to the extremely unfavorable geometry, i.e. the size of the implant relative to the size of the extracorporeal transmitter, the design of such links is highly parametric. Magnetic circuit parameters must be closely matched to the implant's integrated-circuit power usage. In addition, the bandwidth of the communication channel must be adequate to meet the data collection requirements. This paper describes on-going R&D work for the design and fabrication of smart sensors based upon microtelemetry technology. Presently, sensor designs for two applications are in progress -- EMG and joint angle position.

  18. Synthesis of CAD\\/CAM, robotics and biomaterial implant fabrication: single-step reconstruction in computer aided frontotemporal bone resection

    Microsoft Academic Search

    Stephan Weihe; Michael Wehmöller; Henning Schliephake; Stefan Haßfeld; Alexander Tschakaloff; Jörg Raczkowsky; Harald Eufinger

    2000-01-01

    The preoperative manufacturing of individual skull implants, developed by an interdisciplinary research group at Ruhr-University Bochum, is based on the use of titanium as the most common material for implants at present. Using the existing technology for materials that can be milled or moulded, customized implants may be manufactured as well. The goal of the study was to examine biodegradable

  19. Fully Implantable Blood Pressure System: Implantation Experiences

    Microsoft Academic Search

    U. Urban; R. Ballan; H. Fassbender; P. Fuerst; T. Goettsche; B. Bender; R. Becker; W. Mokwa; H. K. Trieu; P. Osypka; R. Glocker; U. Steinseifer; T. Schmitz-Rode

    \\u000a Hypertension is an important risk factor for vascular diseases (arteriosclerosis), renal and heart insufficiency. In Germany,\\u000a approximately 10 million people suffer from hypertension. 10% of the people affected are difficult to medicate. Furthermore,\\u000a 10% of this group are candidates for long term monitoring. Therefore a fully implantable and telemetrically controlled blood\\u000a pressure system is presented to realize a comfortable long

  20. Maxillary Overdentures Supported by Four Splinted Direct Metal Laser Sintering Implants: A 3-Year Prospective Clinical Study

    PubMed Central

    Mangano, Francesco; Shibli, Jamil Awad; Anil, Sukumaran

    2014-01-01

    Purpose. Nowadays, the advancements in direct metal laser sintering (DMLS) technology allow the fabrication of titanium dental implants. The aim of this study was to evaluate implant survival, complications, and peri-implant marginal bone loss of DMLS implants used to support bar-retained maxillary overdentures. Materials and Methods. Over a 2-year period, 120 implants were placed in the maxilla of 30 patients (18 males, 12 females) to support bar-retained maxillary overdentures (ODs). Each OD was supported by 4 implants splinted by a rigid cobalt-chrome bar. At each annual follow-up session, clinical and radiographic parameters were assessed. The outcome measures were implant failure, biological and prosthetic complications, and peri-implant marginal bone loss (distance between the implant shoulder and the first visible bone-to-implant contact, DIB). Results. The 3-year implant survival rate was 97.4% (implant-based) and 92.9% (patient-based). Three implants failed. The incidence of biological complication was 3.5% (implant-based) and 7.1% (patient-based). The incidence of prosthetic complication was 17.8% (patient-based). No detrimental effects on marginal bone level were evidenced. Conclusions. The use of 4 DMLS titanium implants to support bar-retained maxillary ODs seems to represent a safe and successful procedure. Long-term clinical studies on a larger sample of patients are needed to confirm these results. PMID:25580124

  1. A 2-D enlarged cell technique (ECT) for elastic wave modelling on a curved free surface

    NASA Astrophysics Data System (ADS)

    Wei, Songlin; Zhuang, Mingwei; Zhou, Jianyang; Liu, Qing Huo

    2015-04-01

    The conventional finite-difference time-domain (FDTD) method for elastic waves suffers from the staircasing error when applied to model a curved free surface because of the structured grid. This is similar to the situation for the FDTD method in electromagnetics when it is applied to model a curved perfect conductor surface, where the conformal FDTD methods have been recently developed to avoid this error. In this work a stable and second-order accurate 2-D FDTD method for elastic wave modelling on a curved free surface is presented based on the finite volume method and enlarged cell technique (ECT). To achieve a sufficiently accurate implementation, a finite volume scheme is applied to the curved free surface to remove the staircasing error; in the meantime, to achieve the same stability as the FDTD method without reducing the time step increment, the ECT is introduced to preserve the solution stability even for small irregular cells. This method is verified by several 2-D numerical examples. Results show that the method is second-order accurate and stable at the Courant stability limit for a regular FDTD grid.

  2. Somatic therapies for treatment-resistant depression: ECT, TMS, VNS, DBS

    PubMed Central

    2012-01-01

    The field of non-pharmacological therapies for treatment resistant depression (TRD) is rapidly evolving and new somatic therapies are valuable options for patients who have failed numerous other treatments. A major challenge for clinicians (and patients alike) is how to integrate the results from published clinical trials in the clinical decision-making process. We reviewed the literature for articles reporting results for clinical trials in particular efficacy data, contraindications and side effects of somatic therapies including electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), vagal nerve stimulation (VNS) and deep brain stimulation (DBS). Each of these devices has an indication for patients with different level of treatment resistance, based on acuteness of illness, likelihood of response, costs and associated risks. ECT is widely available and its effects are relatively rapid in severe TRD, but its cognitive adverse effects may be cumbersome. TMS is safe and well tolerated, and it has been approved by FDA for adults who have failed to respond to one antidepressant, but its use in TRD is still controversial as it is not supported by rigorous double-blind randomized clinical trials. The options requiring surgical approach are VNS and DBS. VNS has been FDA-approved for TRD, however it is not indicated for management of acute illness. DBS for TRD is still an experimental area of investigation and double-blind clinical trials are underway. PMID:22901565

  3. Somatic therapies for treatment-resistant depression: ECT, TMS, VNS, DBS.

    PubMed

    Cusin, Cristina; Dougherty, Darin D

    2012-01-01

    The field of non-pharmacological therapies for treatment resistant depression (TRD) is rapidly evolving and new somatic therapies are valuable options for patients who have failed numerous other treatments. A major challenge for clinicians (and patients alike) is how to integrate the results from published clinical trials in the clinical decision-making process.We reviewed the literature for articles reporting results for clinical trials in particular efficacy data, contraindications and side effects of somatic therapies including electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), vagal nerve stimulation (VNS) and deep brain stimulation (DBS). Each of these devices has an indication for patients with different level of treatment resistance, based on acuteness of illness, likelihood of response, costs and associated risks. ECT is widely available and its effects are relatively rapid in severe TRD, but its cognitive adverse effects may be cumbersome. TMS is safe and well tolerated, and it has been approved by FDA for adults who have failed to respond to one antidepressant, but its use in TRD is still controversial as it is not supported by rigorous double-blind randomized clinical trials. The options requiring surgical approach are VNS and DBS. VNS has been FDA-approved for TRD, however it is not indicated for management of acute illness. DBS for TRD is still an experimental area of investigation and double-blind clinical trials are underway. PMID:22901565

  4. Current Internet Technology and Statistics | Blessing or Curse? Jurgen Symanzik

    E-print Network

    Symanzik, Jürgen

    Current Internet Technology and Statistics | Blessing or Curse? Jurgen Symanzik George Mason overview on the history of the Internet and some of its main features. In the second part, we introduce exist- ingInternet technology that e ects todays education and research in Statistics. Examples

  5. Science and technology news Nanotechnology

    E-print Network

    Rogers, John A.

    Science and technology news Home Nanotechnology Physics Space & Earth Electronics Technology Chemistry Biology Medicine & Health Other Sciences Psychology & Psychiatry Research Medications Cancer of neurology at the University of Pennsylvania School of Medicine in Philadelphia. The silk-based implants

  6. Laser Additive Manufacturing of Modified Implant Surfaces with Osseointegrative Characteristics

    NASA Astrophysics Data System (ADS)

    Emmelmann, C.; Scheinemann, P.; Munsch, M.; Seyda, V.

    Additive Manufacturing technology, such as Selective Laser Melting, allows fabrication of complex metal parts with freeform surfaces. Using biocompatible metal alloys, e.g. TiAl6V4, medical implants can be produced. To increase osseointegrative behavior the ability to fabricate filigree lattice structures can be utilized to achieve a modified implant surface. In order to increase dimensional accuracy when applying a lattice structure on a curved surface, process constraints for single lattice bars are studied. The investigated lattice structure was thereupon applied on the surface of a medical implant.

  7. Screw- versus cement-retained implant restorations: current concepts.

    PubMed

    Lee, Angie; Okayasu, Kozue; Wang, Hom-Lay

    2010-02-01

    The debate between screw- versus cement-retained implant prostheses has long been discussed but the best type of implant prosthesis remains controversial among practitioners. An understanding of their properties will help the clinician in selecting the ideal prosthesis for each clinical case while promoting final esthetic outcomes. With the evolving technology and knowledge, an update of the current trends is necessary. This article provides an overview of the different characteristics of screw- and cement-retained implant restorations, and how they may influence the esthetics, retrievability, retention, passivity, occlusion, accessibility, cost, and provisional restorations. Problems and complications frequently encountered are discussed and treatment solutions are proposed. PMID:20147811

  8. Nanostructured ceramics for biomedical implants.

    PubMed

    Catledge, Shane A; Fries, Marc D; Vohra, Yogesh K; Lacefield, William R; Lemons, Jack E; Woodard, Shanna; Venugopalan, Ramakrishna

    2002-01-01

    Recent progress in the synthesis, characterization, and biological compatibility of nanostructured ceramics for biomedical implants is reviewed. A major goal is to develop ceramic coating technology that can reduce the friction and wear in mating total joint replacement components, thus contributing to their significantly improved function and longer life span. Particular attention is focused on the enhancement of mechanical properties such as hardness, toughness, and friction coefficient and on the bioactivity as they pertain to the nanostructure of the material. The development of three nanostructured implant coatings is discussed: diamond, hydroxyapatite, and functionally graded metalloceramics based on the Cr-Ti-N ternary system. Nanostructured diamond produced by chemical vapor deposition (CVD) techniques and composed of nano-size diamond grains have particular promise because of the combination of ultrahigh hardness, improved toughness over conventional microcrystalline diamond, low friction, and good adhesion to titanium alloys. Nanostructured processing applied to hydroxyapatite coatings is used to achieve the desired mechanical characteristics and enhanced surface reactivity and has been found to increase osteoblast adhesion, proliferation, and mineralization. Finally, nanostructured metalloceramic coatings provide continuous variation from a nanocrystalline metallic bond at the interface to the hard ceramic bond on the surface and have the ability to overcome adhesion problems associated with ceramic hard coatings on metallic substrates. PMID:12908255

  9. REVIEW ARTICLE: Medical implants based on microsystems

    NASA Astrophysics Data System (ADS)

    Mokwa, W.

    2007-05-01

    The fast development of CMOS technologies to smaller dimensions led to very high integration densities with complex circuitry on very small chip areas. In 2006 Intel fabricated the first products in a 65 nm technology. The cointegration of microsensors or actuators together with the very low power consumption of the CMOS circuitry is very well suited for use in implanted systems. Applications like intracranial or intraocular pressure measurements have become possible. This review presents an overview over actual applications and developments of sensor/actuator-based microsystems for medical implants. It concentrates on the technical part of these investigations. It will mainly review work on systems measuring pressure in blood vessels and on systems for ophthalmic applications.

  10. Ion-implanted laser annealed silicon solar cells

    Microsoft Academic Search

    J. S. Katzeff

    1980-01-01

    Development of low cost solar cells fabrication technology is being sponsored by NASA JPL as part of the Low Cost Solar Array Project (LSA). In conformance to Project requirements ion implantation and laser annealing were evaluated as junction formation techniques offering low cost-high throughput potential. Properties of cells fabricated utilizing this technology were analyzed by electrical, transmission electron microscopy, Rutherford

  11. Positron implantation in solids

    SciTech Connect

    Ghosh, V.J.; Lynn, K.G.; Welch, D.O.

    1993-12-31

    The Monte Carlo technique for modeling positron prior to annihilation and electron implantation in semi-infinite metals is described. Particle implantation is modelled as a multistep process, a series of collisions with the atoms of the host material. In elastic collisions with neutral atoms there is no transfer of energy. The particle loses energy by several different channels, excitation of the electron gas, ionization of the ion cores, or, at low energies, by phonon excitation. These competing scattering mechanisms have been incorporated into the Monte Carlo framework and several different models are being used. Brief descriptions of these Monte Carlo schemes, as well as an analytic model for positron implantation are included. Results of the Monte Carlo simulations are presented and compared with expermental data. Problems associated with modeling positron implantation are discuss and the need for more expermental data on energy-loss in different materials is stressed. Positron implantation in multilayers of different metals is briefly described and extensions of this work to include a study of multilayers and heterostructures is suggested.

  12. A wireless implantable passive strain sensor system

    Microsoft Academic Search

    F. Umbrecht; M. Wendlandt; D. Juncker; C. Hierold; J. Neuenschwander

    2005-01-01

    A design study of a novel passive strain-sensor technology for the in-situ measurement of small strains on implants, bones or fixation systems is presented. The sensing principle is based on hydro-mechanical strain amplification which allows for the abandonment of any electrical circuits. Thus, the sensor can be fabricated applying solely biocompatible or bioresorbable polymeric materials. Finite element simulations are employed

  13. Improved osseointegration in ion implantation-treated dental implants

    Microsoft Academic Search

    I Braceras; J. I Alava; J. I Oñate; M Brizuela; A Garcia-Luis; N Garagorri; J. L Viviente; M. A de Maeztu

    2002-01-01

    Implants for knee, hip and dental part replacement are becoming increasingly used in surgery. Unfortunately, their use is sometimes accompanied by failure due to infection, inflammation, integration problems with the surrounding tissues or bone, and implant failure due to mishandling. Surface treatment, such as ion implantation, has been identified as a good candidate to modify the surface properties of the

  14. 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. Module A: Fundamentals of Marine Biology and Ecology (15 ECTS) Modul

    E-print Network

    Hoffmeister, Thomas S.

    1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. Module A: Fundamentals of Marine Biology and Ecology Biology and Biological Oceanography Principles of Marine Ecophysiology Experimental Design & Data Analysis: Advanced Studies in Marine Biology (18 ECTS) Module G: Project Development & Implementation (9 ECTS

  15. Feasibility and safety of electrochemotherapy (ECT) in the pancreas: a pre-clinical investigation

    PubMed Central

    Girelli, Roberto; Prejanò, Simona; Cataldo, Ivana; Corbo, Vincenzo; Martini, Lucia; Scarpa, Aldo; Claudio, Bassi

    2015-01-01

    Background. Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease generally refractory to standard chemotherapeutic agents; therefore improvements in anticancer therapies are mandatory. A major determinant of therapeutic resistance in PDAC is the poor drug delivery to neoplastic cells, mainly due to an extensive fibrotic reaction. Electroporation can be used in vivo to increase cancer cells’ local uptake of chemotherapeutics (electrochemotherapy, ECT), thus leading to an enhanced tumour response rate. In the present study, we evaluated the in vivo effects of reversible electroporation in normal pancreas in a rabbit experimental model. We also tested the effect of electroporation on pancreatic cancer cell lines in order to evaluate their increased sensitivity to chemotherapeutic agents. Materials and methods. The application in vivo of the European Standard Operating Procedure of Electrochemotherapy (ESOPE) pulse protocol (1000 V/cm, 8 pulses, 100 ?s, 5 KHz) was tested on the pancreas of normal New Zealand White Rabbits and short and long-term toxicity were assessed. PANC1 and MiaPaCa2 cell lines were tested for in vitro electrochemotherapy experiments with and without electroporation. Levels of cell permeabilization were determined by flow cytometry, whereas cell viability and drug (cisplatin and bleomycin) sensitivity of pulsed cells were measured by 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) assay. Results. In healthy rabbits, neither systemic nor local toxic effects due to the electroporation procedure were observed, demonstrating the safety of the optimized electric parameters in the treatment of the pancreas in vivo. In parallel, we established an optimized protocol for ECT in vitro that determined an enhanced anti-cancer effect of bleomycin and cisplatin with respect to treatment without electroporation. Conclusions. Our data suggest that electroporation is a safe procedure in the treatment of PDAC because it does not affect normal pancreatic parenchyma, but has a potentiating effect on cytotoxicity of bleomycin in pancreatic tumour cell lines. Therefore, ECT could be considered as a valid alternative for the local control of non-resectable pancreatic cancer. PMID:26029026

  16. Ion implantation in silicate glasses

    SciTech Connect

    Arnold, G.W.

    1993-12-01

    This review examines the effects of ion implantation on the physical properties of silicate glasses, the compositional modifications that can be brought about, and the use of metal implants to form colloidal nanosize particles for increasing the nonlinear refractive index.

  17. Rehabilitation using single stage implants

    PubMed Central

    Mohamed, Jumshad B.; Sudarsan, Sabitha; Arun, K. V.; Shivakumar, B.

    2009-01-01

    Implant related prosthesis has become an integral part of rehabilitation of edentulous areas. Single stage implant placement has become popular because of its ease of use and fairly predictable results. In this paper, we present a series of cases of single stage implants being used to rehabilitate different clinical situations. All the implants placed have been successfully restored and followed up for up to one year. PMID:20376239

  18. Hydroxylapatite Otologic Implants

    SciTech Connect

    McMillan, A.D.; Lauf, R.J.; Beale, B.; Johnson, R.

    2000-01-01

    A Cooperative Research and Development Agreement (CRADA) between Lockheed Martin Energy Research Corporation (LMER) and Smith and Nephew Richards Inc. of Bartlett, TN, was initiated in March 1997. The original completion date for the Agreement was March 25, 1998. The purpose of this work is to develop and commercialize net shape forming methods for directly creating dense hydroxylapatite (HA) ceramic otologic implants. The project includes three tasks: (1) modification of existing gelcasting formulations to accommodate HA slurries; (2) demonstration of gelcasting to fabricate green HA ceramic components of a size and shape appropriate to otologic implants: and (3) sintering and evaluation of the HA components.

  19. Technology.

    ERIC Educational Resources Information Center

    Online-Offline, 1998

    1998-01-01

    Focuses on technology, on advances in such areas as aeronautics, electronics, physics, the space sciences, as well as computers and the attendant progress in medicine, robotics, and artificial intelligence. Describes educational resources for elementary and middle school students, including Web sites, CD-ROMs and software, videotapes, books,…

  20. Haemocompatibility optimisation of implants by hybrid structuring.

    PubMed

    Bolz, A; Schaldach, M

    1993-07-01

    State of the art in biomaterial research and implant design is a compromise between functionality and biocompatibility. Consequently, results often have disadvantages with respect to both aspects. With regard to biocompatibility, the activation of the clotting system by alloplastic materials is of great significance, because it necessitates anticoagulant therapy. Further improvements in implant technology require an understanding of the interactions between blood and implants. Therefore a microscopic model of thrombogenesis at alloplastic surfaces is briefly presented, relating thrombogenicity of a material to the electronic structure of its surface. The electronic requirements for high haemocompatibility, which result from this model (especially a low band-gap density of states and a high surface conductivity) are fulfilled by an amorphous alloy of silicon and carbon (a-SiC:H). The advantage of amorphous materials is that they do not obey stoichiometric rules. Thus they allow a continuous adjustment of the electronic parameters without fundamental changes in their mechanical and chemical properties. The theoretical results were checked in vitro by total internal reflection intrinsic fluorescence (TIRIF) spectroscopy as well as thrombelastography experiments (TEG). In comparison with conventional materials such as titanium or LTI carbon, the TEG-clotting time of a-SiC:H-coatings was prolonged by in excess of 200 per cent. As a consequence, a-SiC:H is well suited as a haemocompatible coating material for hybrid structuring of cardiovascular implants. PMID:8231315

  1. Developmental neuroplasticity after cochlear implantation

    E-print Network

    Allen, Jont

    Developmental neuroplasticity after cochlear implantation Andrej Kral1,2 and Anu Sharma3 1. Cochlear implants bypass cochlear damage by directly stimulating the auditory nerve and brain, making, and mechanistic constraints on, sensi- tive periods for cochlear implantation and describe the effects

  2. Treatment of peri-implantitis and the failing implant.

    PubMed

    Robertson, Kevin; Shahbazian, Timothy; MacLeod, Stephen

    2015-04-01

    Appropriate treatment of implants is becoming increasingly important for the general dentist as the number of implants placed per year continues to increase. Early diagnosis of peri-implantitis is imperative; initiating the correct treatment protocol depends on a proper diagnosis. Several risk factors exist for the development of peri-implantitis, which can guide patient selection and treatment planning. Treatment of peri-implantitis should be tailored to the severity of the lesion (as outlined by the cumulative interceptive supportive treatment protocol), ranging from mechanical debridement to explantation. Several surgical and nonsurgical treatment alternatives exist. There is little consensus on superior treatment methods. PMID:25835797

  3. Evaluation of imaging protocol for ECT based on CS image reconstruction algorithm

    E-print Network

    Zhou, Xiaolin; Cao, Xuexiang; Liu, Shuangquan; Wang, Lu; Huang, Xianchao; Wei, Long

    2013-01-01

    SPECT (Single-photon Emission Computerized Tomography) and PET (Positron Emission Tomography) are essential medical imaging tools, for which the sampling angle number, scan time should be chosen carefully to compromise between image quality and the radiopharmaceutical dose. In this study, the image quality of different acquisition protocol was evaluated via varied angle number and count number per angle with Monte Carlo simulation data. It was shown that when similar imaging counts were used, the factor of acquisition counts was more important than that of the sampling number in ECT (Emission Computerized Tomography). To further reduce the activity requirement and the scan duration, an iterative image reconstruction algorithm for limited-view and low-dose tomography based on compressed sensing theory has been developed. The total variation regulation was added in the reconstruction process to improve SNR (Signal to Noise Ratio) and reduce the artifacts caused by the limited angle sampling. Maximization of max...

  4. eCT: THE B2C E-COMMERCE TOOLKIT for the WebComfort Platform

    E-print Network

    da Silva, Alberto Rodrigues

    eCT: THE B2C E-COMMERCE TOOLKIT for the WebComfort Platform Frederico de Carvalho Baptista, Jo.silva@acm.org Keywords: e-Commerce, WebComfort, content management systems (CMS), e-commerce extensions for CMS Abstract: Electronic commerce (e-Commerce) involves a complex set of business workflows regarding the buying

  5. Marc Normatiu del Projecte Final de Master El Projecte s una assignatura obligatria de 30 ECTS del Mster en

    E-print Network

    Hurtado, Ferran

    projecte podrà ser de 15 ECTS. 1. Definició i característiques El Projecte Final de Màster (PFM) ha de Màster. La defensa del PFM es realitzarà davant un tribunal de tres doctors o doctores que valoraran comunicació oral i escrita de l'estudiant/a. Quant al seu contingut, el PFM haurà de centrar-se en un tema

  6. E ect of Carboxylation on Carbon Nanotube Aqueous Dispersibility: A Predictive Coarse-Grained Molecular Dynamics Approach

    E-print Network

    Nielsen, Steven O.

    E ect of Carboxylation on Carbon Nanotube Aqueous Dispersibility: A Predictive Coarse single-walled carbon nanotubes (SWNTs) are widely applied in biomedical science. To understand-scale MD studies of biological systems. INTRODUCTION Single-walled carbon nanotubes (SWNTs) have drawn

  7. Aharonov--Bohm E#ect in Scattering by a Chain of Point--like Magnetic Fields

    E-print Network

    Aharonov--Bohm E#ect in Scattering by a Chain of Point--like Magnetic Fields Hiroshi T. Ito the scattering by several point--like magnetic fields at large separation in two dimensions. We derive. Even if a magnetic field is compactly supported, the corresponding vector potential does

  8. Rounding E#ects in Record Statistics G. Wergen, 1 D. Volovik, 2 S. Redner, 2 and J. Krug 1

    E-print Network

    Redner, Sidney

    Rounding E#ects in Record Statistics G. Wergen, 1 D. Volovik, 2 S. Redner, 2 and J. Krug 1 1 and Department of Physics, Boston University, Boston, MA 02215,USA (Dated: June 20, 2012) We analyze record to integer multiples of a discretization scale # > 0. Rounding leads to ties of an existing record, thereby

  9. ePUB: Modellierung Molecular Life Sciences Master Major 90 ECTS-Credits with special qualification in Plant Physiology

    E-print Network

    Richner, Heinz

    in Plant Physiology [Reglement 01.10.2005] Seite 1 1. Teil: Struktur des Studiums (Prüfungsfächer Physiology, Universität Bern ePUB - interne Bezeichnung: MLS M Major 90 ECTS Plant Physiology [MLSMA Module general topics Module special qualification Plant Physiology 2. Teil: Struktur der Leistungen

  10. Monte Carlo Study of the E ects of Design Parameters on the Sensitivity of a CMB Polarization Experiment

    E-print Network

    Monte Carlo Study of the E#11;ects of Design Parameters on the Sensitivity of a CMB Polarization a monte carlo to simulate Cosmic Microwave Background polarization maps on caps around the North Celestial Pole. We used this monte carlo to explore how the sensitivity of a single parameter #12;t depends

  11. Studies of rejected dental Ti-implants by laser microspectral analysis

    NASA Astrophysics Data System (ADS)

    Surmenko, Elena L.; Tuchin, Valery V.; Sokolova, Tatiana N.; Seryanov, Yury V.

    2003-10-01

    The surface of rejected dental implants was studied. It was clarified that the implant rejection happened in a case of incomplete osteointegration of implants, incomplete proliferation of a bone tissue in holes. In a turn, osteointegration depends on uniformity of deposition of a titanium-hydroxyapatite (Ti/HA) coating and the impurities composition of used materials. The excess of exterior elements imported at technological processes also influences on adhesion.

  12. Ethical, Legal and Social Aspects of Brain-Implants Using Nano-Scale Materials and Techniques

    Microsoft Academic Search

    Francois Berger; Sjef Gevers; Ludwig Siep; Klaus-Michael Weltring

    2008-01-01

    Nanotechnology is an important platform technology which will add new features like improved biocompatibility, smaller size,\\u000a and more sophisticated electronics to neuro-implants improving their therapeutic potential. Especially in view of possible\\u000a advantages for patients, research and development of nanotechnologically improved neuro implants is a moral obligation. However,\\u000a the development of brain implants by itself touches many ethical, social and legal

  13. Bilateral Poly Implant Prothèse Implant Rupture: An Uncommon Presentation

    PubMed Central

    Mallon, Peter; Ganachaud, François; Malhaire, Caroline; Brunel, Raphael; Sigal-Zafrani, Brigitte; Feron, Jean-Guillaume; Couturaud, Benoit; Fitoussi, Alfred

    2013-01-01

    Summary: A woman in her 50s underwent delayed bilateral Poly Implant Prothèse implant reconstruction following mastectomy for breast cancer. Symptoms of implant rupture developed 43 months after surgery with an erythematous rash on her trunk. The rash then spread to her reconstructed breast mounds. Initial ultrasound scan and magnetic resonance imaging were normal; however, subsequent magnetic resonance imaging demonstrated left implant rupture only. In theater, following removal of both implants, both were found to be ruptured. The rash on her trunk resolved within 3 weeks in the postoperative period. Chemical analyses of silicone in both implants confirmed a nonauthorized silicone source; in addition, the chemical structure was significantly different between the left and right implant, perhaps explaining the variation in presentation. PMID:25289223

  14. STEVENS INSTITUTE OF TECHNOLOGY DEPARTMENT OF MECHANICAL ENGINEERING

    E-print Network

    Fisher, Frank

    diagnosis and treatment approaches to glaucoma, based on implantable Microelectromechanical systems (MEMS coating. These emerging technologies offer several new opportunities for the treatment of glaucoma applications. His current research interests include implantable wireless micro and nanosystems for glaucoma

  15. The development of the Nucleus Freedom Cochlear implant system.

    PubMed

    Patrick, James F; Busby, Peter A; Gibson, Peter J

    2006-12-01

    Cochlear Limited (Cochlear) released the fourth-generation cochlear implant system, Nucleus Freedom, in 2005. Freedom is based on 25 years of experience in cochlear implant research and development and incorporates advances in medicine, implantable materials, electronic technology, and sound coding. This article presents the development of Cochlear's implant systems, with an overview of the first 3 generations, and details of the Freedom system: the CI24RE receiver-stimulator, the Contour Advance electrode, the modular Freedom processor, the available speech coding strategies, the input processing options of Smart Sound to improve the signal before coding as electrical signals, and the programming software. Preliminary results from multicenter studies with the Freedom system are reported, demonstrating better levels of performance compared with the previous systems. The final section presents the most recent implant reliability data, with the early findings at 18 months showing improved reliability of the Freedom implant compared with the earlier Nucleus 3 System. Also reported are some of the findings of Cochlear's collaborative research programs to improve recipient outcomes. Included are studies showing the benefits from bilateral implants, electroacoustic stimulation using an ipsilateral and/or contralateral hearing aid, advanced speech coding, and streamlined speech processor programming. PMID:17172547

  16. Elementary Implantable Force Sensor

    PubMed Central

    Wachs, Rebecca A.; Ellstein, David; Drazan, John; Healey, Colleen P.; Uhl, Richard L.; Connor, Kenneth A.

    2014-01-01

    Implementing implantable sensors which are robust enough to maintain long term functionality inside the body remains a significant challenge. The ideal implantable sensing system is one which is simple and robust; free from batteries, telemetry, and complex electronics. We have developed an elementary implantable sensor for orthopaedic smart implants. The sensor requires no telemetry and no batteries to communicate wirelessly. It has no on-board signal conditioning electronics. The sensor itself has no electrical connections and thus does not require a hermetic package. The sensor is an elementary L-C resonator which can function as a simple force transducer by using a solid dielectric material of known stiffness between two parallel Archimedean coils. The operating characteristics of the sensors are predicted using a simplified, lumped circuit model. We have demonstrated sensor functionality both in air and in saline. Our preliminary data indicate that the sensor can be reasonably well modeled as a lumped circuit to predict its response to loading. PMID:24883335

  17. [Cochlear implants and tinnitus].

    PubMed

    Olze, H

    2015-04-01

    The cochlear implant became a very successful method of hearing rehabilitation for patients with profound sensorineural hearing loss. The benefits of the CI extend beyond the medical success and positively influence social and psychosocial areas, reflected by an improved HRQoL. Furthermore, variety of studies demonstrated that the tinnitus severity improves in 46-95?% of cases following the cochlear implantation. However, the parameters investigated in such studies are not always standardized or addressed by validated questionnaires, which explains the high outcome variation between the studies. The relationships between HRQoL and tinnitus distress before and after cochlear implantation have not been well studied. Nevertheless, it is believed that the improvement in HRQoL following CI affects particularly tinnitus.However, an existing tinnitus can also worsen or occur for the first time after the surgery. Since neither tinnitus frequency nor tinnitus loudness correlate with the tinnitus-induced distress, the measurement of HRQoL, distress factors, stress reactions and psychiatric comorbidities appears to be the meaningful assessment of positive or negative effects of CI on tinnitus.Initial studies demonstrated that also patients with unilateral hearing loss may benefit from CI supply, as shown by an improvement in HRQoL and reduction of tinnitus-induced distress. For those patients, who despite CI implantation experience severe tinnitus, there is an option of tinnitus-specific CI-fitting and tinnitus-specific therapy with psychosomatic and psychological approaches, and- in addition- a treatment of possible mental comorbidities. PMID:25862623

  18. Implantable Impedance Plethysmography

    PubMed Central

    Theodor, Michael; Ruh, Dominic; Ocker, Martin; Spether, Dominik; Förster, Katharina; Heilmann, Claudia; Beyersdorf, Friedhelm; Manoli, Yiannos; Zappe, Hans; Seifert, Andreas

    2014-01-01

    We demonstrate by theory, as well as by ex vivo and in vivo measurements that impedance plethysmography, applied extravascularly directly on large arteries, is a viable method for monitoring various cardiovascular parameters, such as blood pressure, with high accuracy. The sensor is designed as an implant to monitor cardiac events and arteriosclerotic progression over the long term. PMID:25123467

  19. Implantable Drug Dispenser

    NASA Technical Reports Server (NTRS)

    Collins, E. R. J.

    1983-01-01

    Drugs such as insulin are injected as needed directly into bloodstream by compact implantable dispensing unit. Two vapor cavities produce opposing forces on drug-chamber diaphragm. Heaters in cavities allow control of direction and rate of motion of bellows. Dispensing capsule fitted with coil so batteries can be recharged by induction.

  20. Implantable electrical device

    NASA Technical Reports Server (NTRS)

    Jhabvala, M. D. (inventor)

    1982-01-01

    A fully implantable and self contained device is disclosed composed of a flexible electrode array for surrounding damaged nerves and a signal generator for driving the electrode array with periodic electrical impulses of nanoampere magnitude to induce regeneration of the damaged nerves.

  1. Implantable biohybrid artificial organs

    Microsoft Academic Search

    Clark K. Colton

    1995-01-01

    Biohybrid artificial organs encompass all devices which substitute for an organ or tissue function and incorporate both synthetic materials and living cells. This review concerns implantable immunoisolation devices in which the tissue is protected from immune rejection by enclosure within a semipermeable membrane. Two critical areas are discussed in detail: (i) Device design and performance as it relates to maintenance

  2. Peritoneal trophoblastic implant.

    PubMed

    Rachagan, S P; Kutty, K; Govindan, K S

    1997-09-01

    A case of persistent trophoblastic tissue on the pelvic peritoneum is presented. While most cases are secondary to conservative surgery for tubal ectopic pregnancy, primary implantation can also occur as highlighted by this case. A brief pathophysiology of the condition is presented. The importance of monitoring the serum for beta subunit human chorionic gonadotrophin (HCG) is emphasised. PMID:10968101

  3. Remote actuated valve implant

    DOEpatents

    McKnight, Timothy E; Johnson, Anthony; Moise, Jr., Kenneth J; Ericson, Milton Nance; Baba, Justin S; Wilgen, John B; Evans, III, Boyd McCutchen

    2014-02-25

    Valve implant systems positionable within a flow passage, the systems having an inlet, an outlet, and a remotely activatable valve between the inlet and outlet, with the valves being operable to provide intermittent occlusion of the flow path. A remote field is applied to provide thermal or magnetic activation of the valves.

  4. Silicon induces minimal thromboinflammatory response during 28-day intravascular implant testing

    PubMed Central

    Melvin, Melissa E.; Fissell, William H; Roy, Shuvo; Brown, David L

    2015-01-01

    Microelectromechanical systems (MEMS) are used to machine miniaturized implantable medical devices. Our group has used MEMS technology to develop hemofiltration membranes for use in renal replacement therapy which possess enhanced selectivity and permeability. The use of silicon in blood-contacting environments may be limited, however, due to contact activation of the coagulation cascade by silicon which form the surface oxides in atmospheric conditions. As well, reports of long-term biocompatibility of blood-contacting silicon devices are lacking. The aims of this pilot study were: 1) to develop a model for investigating the effects of intravascular implants and 2) to characterize the degree of thrombosis and tissue inflammation incited by prolonged implantation of silicon materials. Silicon implants with and without polyethylene glycol (PEG) coatings were surgically implanted transluminally through rat femoral veins. Gore-Tex and stainless steel implants served as controls. Implants were left in vivo for four weeks. All femoral veins remained patent. Veins associated with silicon implants exhibited rare thrombi and occasional mild perivascular inflammation. In contrast, Gore-Tex and stainless steel controls caused moderate vein thrombosis and provoked a moderate to marked cellular infiltrate. Under scanning electron microscopy, bare silicon implants were found to have significant adherent microthrombi, while PEG-treated implants showed no evidence of thrombi. PEG-treated silicon appears to be biocompatible and holds potential as an excellent material with which to construct an implantable, miniaturized hemofiltration membrane. PMID:20431483

  5. Silicon induces minimal thromboinflammatory response during 28-day intravascular implant testing.

    PubMed

    Melvin, Melissa E; Fissell, William H; Roy, Shuvo; Brown, David L

    2010-01-01

    Microelectromechanical systems (MEMS) are used to machine miniaturized implantable medical devices. Our group has used MEMS technology to develop hemofiltration membranes for use in renal replacement therapy, which possess enhanced selectivity and permeability. The use of silicon in blood-contacting environments may be limited, however, due to contact activation of the coagulation cascade by silicon, which forms the surface oxides in atmospheric conditions. As well, the reports of long-term biocompatibility of blood- contacting silicon devices are lacking. The aims of this pilot study were as follows: 1) to develop a model for investigating the effects of intravascular implants and 2) to characterize the degree of thrombosis and tissue inflammation incited by prolonged implantation of silicon materials. Silicon implants with and without polyethylene glycol (PEG) coatings were surgically implanted transluminally through rat femoral veins. Gore-Tex and stainless steel implants served as controls. The implants were left in vivo for 4 weeks. All femoral veins remained patent. The veins associated with silicon implants exhibited rare thrombi and occasional mild perivascular inflammation. In contrast, Gore-Tex and stainless steel controls caused moderate vein thrombosis and provoked a moderate to marked cellular infiltrate. Under scanning electron microscopy, bare silicon implants were found to have significant adherent microthrombi, whereas PEG-treated implants showed no evidence of thrombi. PEG-treated silicon seems to be biocompatible and holds potential as an excellent material with which to construct an implantable, miniaturized hemofiltration membrane. PMID:20431483

  6. Indirect recoil implantation following nuclear reactions: Theory and potential applications

    NASA Astrophysics Data System (ADS)

    Conlon, T. W.

    1980-04-01

    A general treatment of indirect recoil implantation following nuclear reactions is given for the first time. This method allows implantation into any substrate of a wide range of species produced by nuclear reactions either in a thin sacrificial target or from a solid target. It is demonstrated that this can be done whilst avoiding primary beam damage to the substrate. Two cases are considered, the general one in which non-elastic nuclear reactions produce the recoil species of interest and secondly the special case of elastic recoils. In both cases a number of novel features of the process not previously described are outlined. For example, by controlling the angular acceptance of the substrate for recoil products the method can be tailored to give well controlled implantation profiles very similar to direct implantation (i.e., approximately Gaussian in range) or more extensive depth distributions whose profiles are simply determined by the centre of mass angular distribution of the reaction product. The flux of particles available for implantation is approximately 10 -4 smaller than from direct implantation facilities, but is comparable to the useful implantation dose achieved by the established technique of direct elastic recoil implantation. The radiation damage is little more than that associated with the indirect implant itself in contrast to direct elastic recoil implantation where the potential damage produced often mediates against the use of that technique. The main advantage of this relatively new method over the conventional methods is the wider range of species which can be implanted with minimum damage to the substrate. These include elements which cannot be conveniently produced from ion sources as well as exotic species which cannot be produced other than by nuclear reactions; radioactive species are good examples of both cases. The method could make an impact in a number of areas, for example, for the injection of radioactive isotopes of the substrate in the study of irradiation damage, diffusion and catalysis; thin film technology, device technology, implantation metallurgy and radiotracers are also possible areas of exploitation. A number of applications in the radiotracer area, viz to radiation sensitive materials, specifically for thin layer activation studies, are discussed.

  7. [Complications after cosmetic iris implantation].

    PubMed

    Jonsson, N J; Sahlmüller, M C; Ruokonen, P C; Torun, N; Rieck, P

    2011-05-01

    We report the case of a 37-year-old patient with ocular complications associated with the implantation of cosmetic iris implants. Implantation of silicone iris implants for the purpose of changing iris colour has been performed since 2004. Diaphragms are implanted in the anterior chamber. Up to now only little information exists about side effects of this method. In the literature severe ocular complications shortly after cosmetic iris implantation are reported in single cases. In our case 5 months after surgery optic nerve damage caused by elevated intraocular pressure (IOP) was diagnosed. Nuclear opacity of both lenses and a decreased number of corneal endothelial cells were observed at the first visit. Because of recurrent IOP elevation despite maximum antiglaucoma therapy, explantation of the iris implants was required. Damage to the trabecular meshwork, opacity of the lenses as well as the reduced number of endothelial cells are permanent and will probably lead to further complications like corneal decompensation and progressing glaucoma. PMID:21344246

  8. A novel strategy for long-term implantable artificial pancreas.

    PubMed

    Ricotti, Leonardo; Assaf, Tareq; Menciassi, Arianna; Dario, Paolo

    2011-01-01

    Technology has recently changed type 1 diabetes treatment by introducing several advancements able to improve patients' quality of life. However, despite of several decades of research efforts, the dream of a fully-automated implanted artificial pancreas is quite far from its realization. The need for periodically restoring the implanted battery charge and refilling the implanted insulin reservoir are the main issues, for which invasive surgery, transcutaneous catheters or external portable devices are presently the only solutions. In this paper we propose a novel approach to these issues, describing a totally implanted closed-loop artificial pancreas with a wireless battery charger and a non-invasive strategy for insulin refilling, based on sensorized swallowable "insulin carrier" capsules. Such system has the potential to represent a final solution for diabetes treatment, by fully restoring patients' quality of life. PMID:22254935

  9. Industrial applications of ion implantation into metal surfaces

    SciTech Connect

    Williams, J.M.

    1987-07-01

    The modern materials processing technique, ion implantation, has intriguing and attractive features that stimulate the imaginations of scientists and technologists. Success of the technique for introducing dopants into semiconductors has resulted in a stable and growing infrastructure of capital equipment and skills for use of the technique in the economy. Attention has turned to possible use of ion implantation for modification of nearly all surface related properties of materials - optical, chemical and corrosive, tribological, and several others. This presentation provides an introduction to fundamental aspects of equipment, technique, and materials science of ion implantation. Practical and economic factors pertaining to the technology are discussed. Applications and potential applications are surveyed. There are already available a number of ion-implanted products, including ball-and-roller bearings and races, punches-and-dies, injection screws for plastics molding, etc., of potential interest to the machine tool industry.

  10. SEM analysis of ion implanted SiC

    NASA Astrophysics Data System (ADS)

    Malherbe, Johan B.; van der Berg, N. G.; Botha, A. J.; Friedland, E.; Hlatshwayo, T. T.; Kuhudzai, R. J.; Wendler, E.; Wesch, W.; Chakraborty, P.; da Silveira, E. F.

    2013-11-01

    SiC is a material used in two future energy production technologies, firstly as a photovoltaic layer to harness the UV spectrum in high efficient power solar cells, and secondly as a diffusion barrier material for radioactive fission products in the fuel elements of the next generation of nuclear power plants. For both applications, there is an interest in the implantation of reactive and non-reactive ions into SiC and their effects on the properties of the SiC. In this study 360 keV Ag+, I+ and Xe+ ions were separately implanted into 6H-SiC and in polycrystalline SiC at various substrate temperatures. The implanted samples were also annealed in vacuum at temperatures ranging from 900 °C to 1600 °C for various times. In recent years, there had been significant advances in scanning electron microscopy (SEM) with the introduction of an in-lens detector combined with field emission electron guns. This allows defects in solids, such as radiation damage created by the implanted ions, to be detected with SEM. Cross-sectional SEM images of 6H-SiC wafers implanted with 360 keV Ag+ ions at room temperature and at 600 °C and then vacuum annealed at different temperatures revealed the implanted layers and their thicknesses. A similar result is shown of 360 keV I+ ions implanted at 600 °C into 6H-SiC and annealed at 1600 °C. The 6H-SiC is not amorphized but remained crystalline when implanting at 600 °C. There are differences in the microstructure of 6H-SiC implanted with silver at the two temperatures as well as with reactive iodine ions. Voids (bubbles) are created in the implanted layers into which the precipitation of silver and iodine can occur after annealing of the samples. The crystallinity of the substrate via implantation temperature caused differences in the distribution and size of the voids. Implantation of xenon ions in polycrystalline SiC at 350 °C does not amorphize the substrate as is the case with room temperature heavy ion bombardment. Subsequent annealing of the implanted polycrystalline samples leads to increased thermal etching effects such as grain boundary grooving. Damage due to channelling (or non-channelling) in the different crystallites resulted also in differences in thermal etching in the crystallites.

  11. Pathological aspects of bioresorbable stent implantation.

    PubMed

    Sanchez, Oscar D; Yahagi, Kazuyuki; Byrne, Robert A; Mori, Hiroyoshi; Zarpak, Roya; Wittchow, Eric; Foin, Nicolas; Virmani, Renu; Joner, Michael

    2015-05-19

    The treatment of obstructive coronary artery disease has been revolutionised by the advent of drug-eluting stent therapy. However, concerns remain about complications late after stent implantation including late stent thrombosis, hypersensitivity reactions and neoatherosclerosis. In this respect, the introduction of fully bioresorbable stents (BRS) -which resorb over time and leave the arterial wall free of any metal constraints- represents a potentially important disruptive technology. However, although the concept is intuitively attractive, a thorough understanding of the histopathological changes seen after BRS implantation and an appreciation of comparative changes versus existing metal stent technologies are vital to guide BRS clinical usage. In this respect, translational investigation of polymer chemistry, biomedical engineering, as well as in vitro and in vivo testing in animal models is an important undertaking. This article will review the pathological aspects of BRS implantation with a focus on acute and chronic vascular reactions derived from preclinical animal studies, including insights from in vivo imaging. Finally, potential future directions of this novel therapeutic approach will be discussed. PMID:25983157

  12. Intraoral digital impressions to enhance implant esthetics.

    PubMed

    Hinds, Kenneth F

    2014-09-01

    Providing an accurate soft-tissue transfer for anterior implants is not a new concept; however, it is currently an especially relevant one. There are numerous documented cases in which residual excess cement with cement-retained implant restorations was a contributing cause in periimplantitis. In 2012, Wadhwani et al reported the importance of placing the crown abutment margins supragingivally for ease of cement removal as a possible solution to address this important issue. Therefore, if placement of the crown abutment margin location is imperative, making an impression that reproduces the soft tissue is equally critical. In 1997, this author introduced the "custom impression coping" to achieve such an accurate transfer. Given the wide use of intraoral digital impressions in 2014, this discussion describes how to fabricate a "custom scan body" using that technology to replicate the transition zone in the virtual environment. PMID:25279537

  13. [Plasma immersion ion implantation. A new method for homogeneous surface modification of complex forms of medical implants].

    PubMed

    Mändl, S; Rauschenbach, B

    2000-01-01

    Plasma immersion ion implantation (PIII) is a new method for the inexpensive rapid modification of the near-surface region of medical implants of complex shapes. PIII combines the advantages of conventional plasma and ion beam technologies. This article describes the physical basis of the procedure and the construction of a PIII system, and presents typical PIII parameters. In a number of examples, the use of the PIII to modify the surface of biocompatible materials (chrome-nickel stainless steel, titanium, titanium-aluminium-vanadium alloy) with the aim of reducing wear, increasing biocompatibility or improving adhesion, is described. Finally, the possibilities of combining PIII with other technologies are considered. PMID:10975147

  14. Bone Substitutes for Peri-Implant Defects of Postextraction Implants

    PubMed Central

    Santos, Pâmela Letícia; Gulinelli, Jéssica Lemos; Telles, Cristino da Silva; Betoni Júnior, Walter; Chiacchio Buchignani, Vivian; Queiroz, Thallita Pereira

    2013-01-01

    Placement of implants in fresh sockets is an alternative to try to reduce physiological resorption of alveolar ridge after tooth extraction. This surgery can be used to preserve the bone architecture and also accelerate the restorative procedure. However, the diastasis observed between bone and implant may influence osseointegration. So, autogenous bone graft and/or biomaterials have been used to fill this gap. Considering the importance of bone repair for treatment with implants placed immediately after tooth extraction, this study aimed to present a literature review about biomaterials surrounding immediate dental implants. The search included 56 articles published from 1969 to 2012. The results were based on data analysis and discussion. It was observed that implant fixation immediately after extraction is a reliable alternative to reduce the treatment length of prosthetic restoration. In general, the biomaterial should be used to increase bone/implant contact and enhance osseointegration. PMID:24454377

  15. BF{sub 3} PIII modeling: Implantation, amorphisation and diffusion

    SciTech Connect

    Essa, Z.; Cristiano, F.; Spiegel, Y.; Boulenc, P.; Qiu, Y.; Quillec, M.; Taleb, N.; Burenkov, A.; Hackenberg, M.; Bedel-Pereira, E.; Mortet, V.; Torregrosa, Frank; Tavernier, C. [STMicroelectronics 850 rue Jean Monnet F-38926 Crolles France and LAAS-CNRS 7 av. du Col. Roche 31077 Toulouse (France); LAAS-CNRS 7 av. du Col. Roche 31077 Toulouse (France); IBS av. Gaston Imbert prolongee 13790 Peynier Rousset (France); STMicroelectronics 850 rue Jean Monnet F-38926 Crolles (France); LAAS-CNRS 7 av. du Col. Roche 31077 Toulouse (France); Probion Analysis 37 rue de Fontenay 92220 Bagneux (France); Fraunhofer IISB Schottkystrasse 10, 91058 Erlangen (Germany); LAAS-CNRS 7 av. du Col. Roche 31077 Toulouse (France); IBS av. Gaston Imbert prolongee 13790 Peynier Rousset (France); STMicroelectronics 850 rue Jean Monnet F-38926 Crolles (France)

    2012-11-06

    In the race for highly doped ultra-shallow junctions (USJs) in complementary metal oxide semi-conductor (CMOS) technologies, plasma immersion ion implantation (PIII) is a promising alternative to traditional beamline implantation. Currently, no commercial technology computer aided design (TCAD) process simulator allows modeling the complete USJ fabrication process by PIII, including as-implanted dopant profiles, damage formation, dopant diffusion and activation. In this work, a full simulation of a p-type BF{sub 3} PIII USJ has been carried out. In order to investigate the various physical phenomena mentioned above, process conditions included a high energy/high dose case (10 kV, 5 Multiplication-Sign 10{sup 15} cm{sup -2}), specifically designed to increase damage formation, as well as more technology relevant implant conditions (0.5 kV) for comparison. All implanted samples were annealed at different temperatures and times. As implanted profiles for both boron and fluorine in BF{sub 3} implants were modeled and compared to Secondary Ion Mass Spectrometry (SIMS) measurements. Amorphous/crystalline (a/c) interface depths were measured by transmission electron microscopy (TEM) and successfully simulated. Diffused profiles simulations agreed with SIMS data at low thermal budgets. A boron peak behind the a/c interface was observed in all annealed SIMS profiles for the 10 kV case, indicating boron trapping from EOR defects in this region even after high thermal budgets. TEM measurements on the annealed samples showed an end of range (EOR) defects survival behind the a/c interface, including large dislocation loops (DLs) lying on (001) plane parallel to the surface. In the last part of this work, activation simulations were compared to Hall measurements and confirmed the need to develop a (001) large BICs model.

  16. The socially constructed breast: breast implants and the medical construction of need.

    PubMed

    Jacobson, N

    1998-08-01

    When silicone gel breast implants became the subject of a public health controversy in the early 1990s, the most pressing concern was safety. This paper looks at another, less publicized issue: the need for implants. Using a symbolic interactionist approach, the author explores the social construction of the need for implants by tracing the history of the 3 surgical procedures for which implants were used. Stakeholders in this history constructed need as legitimized individual desire, the form of which shifted with changes in the technological and social context. PMID:9702166

  17. Iatrogenic tumor implantation

    Microsoft Academic Search

    Ying Ma; Ping Bai

    2008-01-01

    Iatrogenic tumor implantation is a condition that results from various medical procedures used during diagnosis or treatment\\u000a of a malignancy. It involves desquamation and dissemination of tumor cells that develop into a local recurrence or distant\\u000a metastasis from the tumor under treatment. The main clinical feature of the condition is nodules at the operation’s porous\\u000a channel or incision, which is

  18. Ion Implant Pinball Game

    NSDL National Science Digital Library

    The magnetic force of the ions can be compared to a pinball machine with three different masses. If the same impulse is applied to each ball, only the one with the ideal mass will "hit" the target. The objective is to describe how the mass affects implantation. This simulation is from Module 026 of the Process & Equipment III Cluster of the MATEC Module Library (MML).

  19. Miniature implantable ultrasonic echosonometer

    NASA Technical Reports Server (NTRS)

    Kojima, G. K. (inventor)

    1978-01-01

    A miniature echosonometer adapted for implantation in the interior of an animal for imaging the internal structure of a organ, tissue or vessel is presented. The echosonometer includes a receiver/transmitter circuit which is coupled to an ultrasonic transducer. Power is coupled to the echosonometer by electromagnetic induction through the animal's skin. Imaging signals from the echosonometer are electromagnetically transmitted through the animal's skin to an external readout apparatus.

  20. Immunogenicity of collagenous implants.

    PubMed

    Meade, K R; Silver, F H

    1990-04-01

    Collagenous biomaterials have been used in our laboratory for treatment of decubitus ulcers, tendon/ligament repair and nerve regeneration. Results of previous studies suggest that implants containing bovine type I collagen enhance repair and regeneration of connective tissue found in different organs. The purpose of this paper is to evaluate the immunological response to type I collagen that is cross-linked using either glutaraldehyde or cyanamide treatment. Humoral and cell mediated responses to type I collagen are evaluated in a rabbit model. Results obtained in this study suggest that antibody levels and cell-mediated response to type I collagen are highest in animals exposed to uncross-linked implant materials and these responses are increased by booster injections of the antigen. Antibody titres to cross-linked collagen are significantly lower than those observed for uncross-linked material. Extensive implant cross-linking does not totally eliminate the humoral response and may lead to a cell-mediated reaction. PMID:2350554

  1. [Neurotology and cochlear implants].

    PubMed

    Merchan, M A

    2015-05-01

    In this review we analyse cochlear implantation in terms of the fundamental aspects of the functioning of the auditory system. Concepts concerning neuronal plasticity applied to electrical stimulation in perinatal and adult deep hypoacusis are reviewed, and the latest scientific bases that justify early implantation following screening for congenital deafness are discussed. Finally, this review aims to serve as an example of the importance of fostering the sub-specialty of neurotology in our milieu, with the aim of bridging some of the gaps between specialties and thus improving both the knowledge in the field of research on auditory pathologies and in the screening of patients. The objectives of this review, targeted above all towards specialists in the field of otorhinolaryngology, are to analyse some significant neurological foundations in order to reach a better understanding of the clinical events that condition the indications and the rehabilitation of patients with cochlear implants, as well as to use this means to foster the growth of the sub-specialty of neurotology. PMID:25912703

  2. Metallic orthopaedic implants and airport metal detectors

    Microsoft Academic Search

    S. Kamineni; S. Legge; H. Ware

    2002-01-01

    Airport security can detect in vivo metallic implants. We hypothesized that a soft tissue shield and fast transit through archway detectors would decrease implant detectability, whereas greater implant mass would increase detectability. Twelve patients with 8 orthopaedic implants in vivo and 60 trauma and arthroplasty implants in vitro were subjected to standard airport security measures at Stanstead Airport (British Airports

  3. Variability of Hydroxyapatite-Coated Dental Implants

    Microsoft Academic Search

    Karlis A. Gross; Chris C. Berndt

    Uniformity, surface roughness, and chemical phase structure are all important features of implant coatings. While the first two variables are important for implant placement, the phase structure affects implant fixation. This study examined the coating morphology and the amount, size, and distribution of crystalline regions of press-fit and screw-type dental implants. Implants obtained from five commercial vendors were sectioned sagitally,

  4. Foreign Body Reactions to Plastic Implants

    Microsoft Academic Search

    David E. Ocumpaugh; Henry L. Lee

    1970-01-01

    There are three types of foreign body reactions to plastic implants: 1) reactions due to physical characteristics of the implant, 2) reactions due directly to chemical properties of the implant, and 3) immune reactions. Responses which vary with the physical properties of the implant are epithelial encapsulation of the plastic, epithelial keratinization in cutaneous implants, thickening of the connective tissue

  5. Hydroxyapatite coatings in implant dentistry.

    PubMed

    Zablotsky, M H

    1992-01-01

    Hydroxyapatite coatings have shown promise due to the enhanced integration of osseous tissues to coated implant surfaces. When compared with healing around commercially pure or titanium alloy implant surfaces, hydroxyapatite-coated implants appear to be superior in sites which are compromised in either quantity or quality of bone. In spite of these encouraging findings, the long-term stability of the hydroxyapatite/bone interface has been challenged. Microbiologically, the hydroxyapatite-coated implant surface may be at an increased risk to bacterial plaque. However, after 8 years of clinical utilization, the hydroxyapatite-coated implant surface has not been shown to be predisposed to increased long-term failure. Available research as it pertains to this controversial area of implant dentistry is reviewed. PMID:1298500

  6. The Effect of Dose Rate and Implant Temperature on Transient Enhanced Diffusion in B Implanted Si

    E-print Network

    Florida, University of

    1361 The Effect of Dose Rate and Implant Temperature on Transient Enhanced Diffusion in B Implanted of ion implantation dose rate and implant temperature on the transientenhanceddiffusion that there is no measurable effect of dose rate or implant temperature on TED of boron implanted silicon for any of the damage

  7. An ECT/ERT dual-modality sensor for oil-water two-phase flow measurement

    NASA Astrophysics Data System (ADS)

    Wang, Pitao; Wang, Huaxiang; Sun, Benyuan; Cui, Ziqiang; Huang, Wenrui

    2014-04-01

    This paper presents a new sensor for ECT/ERT dual-modality system which can simultaneously obtain the permittivity and conductivity of the materials in the pipeline. Quasi-static electromagnetic fields are produced by the inner electrodes array sensor of electrical capacitance tomography (ECT) system. The results of simulation show that the data of permittivity and conductivity can be simultaneously obtained from the same measurement electrode and the fusion of two kinds of data may improve the quality of the reconstructed images. For uniform oil-water mixtures, the performance of designed dual-modality sensor for measuring the various oil fractions has been tested on representative data and the results of experiments show that the designed sensor broadens the measurement range compared to single modality.

  8. Evaluation of imaging protocol for ECT based on CS image reconstruction algorithm

    E-print Network

    Xiaolin Zhou; Minkai Yun; Xuexiang Cao; Shuangquan Liu; Lu Wang; Xianchao Huang; Long Wei

    2013-06-27

    SPECT (Single-photon Emission Computerized Tomography) and PET (Positron Emission Tomography) are essential medical imaging tools, for which the sampling angle number, scan time should be chosen carefully to compromise between image quality and the radiopharmaceutical dose. In this study, the image quality of different acquisition protocol was evaluated via varied angle number and count number per angle with Monte Carlo simulation data. It was shown that when similar imaging counts were used, the factor of acquisition counts was more important than that of the sampling number in ECT (Emission Computerized Tomography). To further reduce the activity requirement and the scan duration, an iterative image reconstruction algorithm for limited-view and low-dose tomography based on compressed sensing theory has been developed. The total variation regulation was added in the reconstruction process to improve SNR (Signal to Noise Ratio) and reduce the artifacts caused by the limited angle sampling. Maximization of maximum likelihood of the estimated image and the measured data and minimization of the total variation of the image are alternative implemented. By using this advanced algorithm, the reconstruction process is able to achieve image quality matching or exceeding that of normal scan with only half of the injection radiopharmaceutical dose.

  9. Implant biomaterials: A comprehensive review.

    PubMed

    Saini, Monika; Singh, Yashpal; Arora, Pooja; Arora, Vipin; Jain, Krati

    2015-01-16

    Appropriate selection of the implant biomaterial is a key factor for long term success of implants. The biologic environment does not accept completely any material so to optimize biologic performance, implants should be selected to reduce the negative biologic response while maintaining adequate function. Every clinician should always gain a thorough knowledge about the different biomaterials used for the dental implants. This article makes an effort to summarize various dental bio-materials which were used in the past and as well as the latest material used now. PMID:25610850

  10. Language outcomes after cochlear implantation.

    PubMed

    Ganek, Hillary; McConkey Robbins, Amy; Niparko, John K

    2012-02-01

    This article presents a focused review of language, speech, and comprehension outcomes in children with cochlear implants. Language acquisition with early-age implants and later-age implants are discussed, along with literacy and comprehension skills. A wide range of language outcomes is possible for children with cochlear implants, but many can achieve listening and spoken language skills at the same rate as their hearing peers. Appropriate auditory rehabilitation and parental guidance is vital for the development of listening and spoken language skills. PMID:22115689

  11. Implant biomaterials: A comprehensive review

    PubMed Central

    Saini, Monika; Singh, Yashpal; Arora, Pooja; Arora, Vipin; Jain, Krati

    2015-01-01

    Appropriate selection of the implant biomaterial is a key factor for long term success of implants. The biologic environment does not accept completely any material so to optimize biologic performance, implants should be selected to reduce the negative biologic response while maintaining adequate function. Every clinician should always gain a thorough knowledge about the different biomaterials used for the dental implants. This article makes an effort to summarize various dental bio-materials which were used in the past and as well as the latest material used now. PMID:25610850

  12. Short implants: A systematic review

    PubMed Central

    Karthikeyan, I.; Desai, Shrikar R.; Singh, Rika

    2012-01-01

    Background: Short implants are manufactured for use in atrophic regions of the jaws. Although many studies report on short implants as ?10 mm length with considerable success, the literature regarding survival rate of ?7 mm is sparse. Purpose: The purpose of this study was to systematically evaluate the publications concerning short dental implants defined as an implant with a length of ?7 mm placed in the maxilla or in the mandible. Materials and Methods: A Medline and manual search was conducted to identify studies concerning short dental implants of length ?7 mm published between 1991 and 2011. The articles included in this study report data on implant length ?7 mm, such as demographic variables, implant type, location in jaws, observation time, prostheses and complications. Results: The 28 included studies represent one randomized controlled trial, 12 prospective studies and 10 retrospective studies. The survival rate of short implant was found to be increased from 80% to 90% gradually, with recent articles showing 100%. Conclusion: When severe atrophy of jaws was encountered, short and wide implants can be placed successfully. PMID:23162320

  13. Characterization of the Edge Crack Torsion (ECT) Test for Mode III Fracture Toughness Measurement of Laminated Composites

    NASA Technical Reports Server (NTRS)

    Ratcliffe, James G.

    2004-01-01

    The edge crack torsion (ECT) test is designed to initiate mode III delamination growth in composite laminates. An ECT specimen is a rectangular laminate, containing an edge delamination at the laminate mid-plane. Torsion load is applied to the specimens, resulting in relative transverse shear sliding of the delaminated faces. The test data reduction schemes are intended to yield initiation values of critical mode III strain energy release rate, G(sub IIIc), that are constant with delamination length. The test has undergone several design changes during its development. The objective of this paper was to determine the suitability of the current ECT test design as a mode III fracture test. To this end, ECT tests were conducted on specimens manufactured from IM7/8552 and specimens made from S2/8552 tape laminates. Several specimens, each with different delamination lengths are tested. Detailed, three-dimensional finite element analyses of the specimens were performed. The analysis results were used to calculate the distribution of mode I, mode II, and mode III strain energy release rate along the delamination front. The results indicated that mode III-dominated delamination growth would be initiated from the specimen center. However, in specimens of both material types, the measured values of G(sub IIIc) exhibited significant dependence on delamination length. Furthermore, there was a large amount of scatter in the data. Load-displacement response of the specimens exhibited significant deviation from linearity before specimen failure. X-radiographs of a sample of specimens revealed that damage was initiated in the specimens prior to failure. Further inspection of the failure surfaces is required to identify the damage and determine that mode III delamination is initiated in the specimens.

  14. An experimental study of the e(ect of hardening on plastic deformation at notch tips in metallic single crystals

    Microsoft Academic Search

    W. C. Crone; T. W. Shield

    Experiments to measure the e(ect of hardening on the plastic deformation 3eld near a notch tip in metallic single crystals were conducted.The specimens were cut from pure Cu and a CuBe alloy (with 1.8-2.0 wt% Be) FCC single crystals. The Cu-2.0wt%Be alloy was selected because its initial hardness and rate of hardening can be modi3ed by heat treatment.The Vick- ers

  15. Emergency delivery of Vasopressin from an implantable MEMS rapid drug delivery device

    E-print Network

    Ho Duc, Hong Linh, 1978-

    2009-01-01

    An implantable rapid drug delivery device based on micro-electro-mechanical systems (MEMS) technology was designed, fabricated and validated for the in vivo rapid delivery of vasopressin in a rabbit model. In vitro ...

  16. Characterization of the Edge Crack Torsion (ECT) Test for Mode III Fracture Toughness Measurement of Laminated Composites

    NASA Technical Reports Server (NTRS)

    Ratcliffe, James G.

    2004-01-01

    The edge crack torsion (ECT) test is designed to initiate mode III delamination growth in composite laminates. The test has undergone several design changes during its development. The objective of this paper was to determine the suitability of the current ECT test design a mode III fracture test. To this end, ECT tests were conducted on specimens manufactured from IM7/8552 and S2/8552 tape laminates. Three-dimensional finite element analyses were performed. The analysis results were used to calculate the distribution of mode I, mode II, and mode III strain energy release rate along the delamination front. The results indicated that mode IIIdominated delamination growth would be initiated from the specimen center. However, in specimens of both material types, the measured values of GIIIc exhibited significant dependence on delamination length. Load-displacement response of the specimens exhibited significant deviation from linearity before specimen failure. X-radiographs of a sample of specimens revealed that damage was initiated in the specimens prior to failure. Further inspection of the failure surfaces is required to identify the damage and determine that mode III delamination is initiated in the specimens.

  17. Research Progress of Subretinal Implant based on Electronic Stimulation

    Microsoft Academic Search

    Wang Xing; Peng Chenglin; Zhao Zhiqiang; Luo Xiaogang; Hu Ning; Zhang Huiquan

    2005-01-01

    Subretinal prosthesis is one kind of retinal prosthesis, which means that a microimplant based on MEMS technology is inserted in the subretinal space to stimulate the optic nerve and elicit an electrical-evoked response on the cortical region. The subretinal implant is made up of extraocular part and intraocular part. As an important part, the latter consists of accessorial setting and

  18. Developing a wireless implantable body sensor network in MICS band.

    PubMed

    Fang, Qiang; Lee, Shuenn-Yuh; Permana, Hans; Ghorbani, Kamran; Cosic, Irena

    2011-07-01

    Through an integration of wireless communication and sensing technologies, the concept of a body sensor network (BSN) was initially proposed in the early decade with the aim to provide an essential technology for wearable, ambulatory, and pervasive health monitoring for elderly people and chronic patients. It has become a hot research area due to big opportunities as well as great challenges it presents. Though the idea of an implantable BSN was proposed in parallel with the on-body sensor network, the development in this area is relatively slow due to the complexity of human body, safety concerns, and some technological bottlenecks such as the design of ultralow-power implantable RF transceiver. This paper describes a new wireless implantable BSN that operates in medical implant communication service (MICS) frequency band. This system innovatively incorporates both sensing and actuation nodes to form a closed-control loop for physiological monitoring and drug delivery for critically ill patients. The sensing node, which is designed using system-on-chip technologies, takes advantage of the newly available ultralow-power Zarlink MICS transceiver for wireless data transmission. Finally, the specific absorption rate distribution of the proposed system was simulated to determine the in vivo electromagnetic field absorption and the power safety limits. PMID:21571615

  19. Transcatheter aortic valve implantation: status and challenges.

    PubMed

    Fishbein, Gregory A; Schoen, Frederick J; Fishbein, Michael C

    2014-01-01

    Calcific aortic valve disease of the elderly is the most prevalent hemodynamically-significant valvular disease, and the most common lesion requiring valve replacement in industrialized countries. Transcatheter aortic valve implantation is a less invasive alternative to classical aortic valve replacement that can provide a therapeutic option for high-risk or inoperable patients with aortic stenosis. These devices must be biocompatible, have excellent hemodynamic performance, be easy to insert, be securely anchored without sutures, and be durable, without increased risk of thrombosis or infection. To date, complications are related to the site of entry for insertion, the site of implantation (aorta, coronary ostia, base of left ventricle), and to the structure and design of the inserted device. However, as with any novel technology unanticipated complications will develop. Goals for future development will be to make the devices more effective, more durable, safer, and easier to implant, so as to further improve outcome for patients with severe aortic stenosis. The pathologist participating in research and development, and examination of excised devices will have a critical role in improving outcome for these patients. PMID:24183003

  20. Single Color Centers Implanted in Diamond Nanostructures

    E-print Network

    Birgit J. M. Hausmann; Thomas M. Babinec; Jennifer T. Choy; Jonathan S. Hodges; Sungkun Hong; Irfan Bulu; A. Yacoby; M. D. Lukin; Marko Lon?ar

    2010-09-21

    The development of materials processing techniques for optical diamond nanostructures containing a single color center is an important problem in quantum science and technology. In this work, we present the combination of ion implantation and top-down diamond nanofabrication in two scenarios: diamond nanopillars and diamond nanowires. The first device consists of a 'shallow' implant (~20nm) to generate Nitrogen-vacancy (NV) color centers near the top surface of the diamond crystal. Individual NV centers are then isolated mechanically by dry etching a regular array of nanopillars in the diamond surface. Photon anti-bunching measurements indicate that a high yield (>10%) of the devices contain a single NV center. The second device demonstrates 'deep' (~1\\mu m) implantation of individual NV centers into pre-fabricated diamond nanowire. The high single photon flux of the nanowire geometry, combined with the low background fluorescence of the ultrapure diamond, allows us to sustain strong photon anti-bunching even at high pump powers.

  1. Focus on Implantation Implantation mechanisms: insights from the sheep

    Microsoft Academic Search

    Thomas E Spencer; Greg A Johnson; Fuller W Bazer; Robert C Burghardt

    Implantation in all mammals involves shedding of the zona pellucida, followed by orientation, apposition, attachment and adhesion of the blastocyst to the endometrium. Endometrial invasion does not occur in domestic ruminants; thus, definitive implantation is achieved by adhesion of the mononuclear trophoblast cells to the endometrial lumenal epithelium (LE) and formation of syncytia by the fusion of trophoblast binucleate cells

  2. Recent Researches of Plasma-based Ion Implantation and Deposition in Japan

    NASA Astrophysics Data System (ADS)

    Yukimura, Ken

    Plasma-based ion implantation technology has been developed for more than 15 years. Recently, the technology has been accompanied by deposition onto a substrate immersed in a metal or semi-metal plasma. The process using this hybrid system is actively researched for cost-effective and simple modification system, in particular, in Japan. Recent trend of plasma-based ion implantation and deposition from hardware of the apparatus to applications through fundamental researches is introduced in the article.

  3. An Unusual Bone Loss Around Implants

    PubMed Central

    Rokn, Amir Reza; Sajedinejad, Neda; Yousefyfakhr, Hosnieh; Badri, Samare

    2013-01-01

    Pre-implant disease is an inflammatory process that affects the surrounding tissues of a functional osseointegrated implant. It is usually the result of a disequilibrium between the micro-flora and the defense system. This case reports a 57-year-old man with unusual bone loss around dental implants. This was an unusual case of peri-implantitis that occurred only in the implants on one side of the mouth although they were all unloaded implants. PMID:24396359

  4. Implantable medical sensor system

    DOEpatents

    Darrow, Christopher B. (Pleasanton, CA); Satcher, Jr., Joe H. (Modesto, CA); Lane, Stephen M. (Oakland, CA); Lee, Abraham P. (Walnut Creek, CA); Wang, Amy W. (Berkeley, CA)

    2001-01-01

    An implantable chemical sensor system for medical applications is described which permits selective recognition of an analyte using an expandable biocompatible sensor, such as a polymer, that undergoes a dimensional change in the presence of the analyte. The expandable polymer is incorporated into an electronic circuit component that changes its properties (e.g., frequency) when the polymer changes dimension. As the circuit changes its characteristics, an external interrogator transmits a signal transdermally to the transducer, and the concentration of the analyte is determined from the measured changes in the circuit. This invention may be used for minimally invasive monitoring of blood glucose levels in diabetic patients.

  5. Broad beam ion implanter

    DOEpatents

    Leung, Ka-Ngo (Hercules, CA)

    1996-01-01

    An ion implantation device for creating a large diameter, homogeneous, ion beam is described, as well as a method for creating same, wherein the device is characterized by extraction of a diverging ion beam and its conversion by ion beam optics to an essentially parallel ion beam. The device comprises a plasma or ion source, an anode and exit aperture, an extraction electrode, a divergence-limiting electrode and an acceleration electrode, as well as the means for connecting a voltage supply to the electrodes.

  6. Bone cement implantation syndrome.

    PubMed

    Razuin, R; Effat, O; Shahidan, M N; Shama, D V; Miswan, M F M

    2013-06-01

    Bone cement implantation syndrome (BCIS) is characterized by hypoxia, hypotension, cardiac arrhythmias, increased pulmonary vascular resistance and cardiac arrest. It is a known cause of morbidity and mortality in patients undergoing cemented orthopaedic surgeries. The rarity of the condition as well as absence of a proper definition has contributed to under-reporting of cases. We report a 59-year-old woman who sustained fracture of the neck of her left femur and underwent an elective hybrid total hip replacement surgery. She collapsed during surgery and was revived only to succumb to death twelve hours later. Post mortem findings showed multiorgan disseminated microembolization of bone marrow and amorphous cement material. PMID:23817399

  7. Broad beam ion implanter

    DOEpatents

    Leung, K.N.

    1996-10-08

    An ion implantation device for creating a large diameter, homogeneous, ion beam is described, as well as a method for creating same, wherein the device is characterized by extraction of a diverging ion beam and its conversion by ion beam optics to an essentially parallel ion beam. The device comprises a plasma or ion source, an anode and exit aperture, an extraction electrode, a divergence-limiting electrode and an acceleration electrode, as well as the means for connecting a voltage supply to the electrodes. 6 figs.

  8. The optimal design of an implant to improve bone quality of implant surroundings based on stress analysis

    NASA Astrophysics Data System (ADS)

    Noyama, Yoshihiro; Nagayama, Noriyuki; Kuramoto, Koichi; Nakano, Takayoshi

    2009-05-01

    Research on how implant surface shape contributes to long-term stability after implantation is important in the field of orthopaedics. In particular, technology that controls various bone quality parameters and voluntary bone inducement in implant surroundings should be developed for the next generation of implants and this will improve the patient's quality of life (QOL). For this research, we focused on the inducement of the appropriate alignment for biological apatite (BAp) crystallites and related collagen (Col.) fibres as a bone quality parameter. In this study, we predicted that when stress is applied to bone, the BAp/Col. preferential alignment can be formed if osteocytes are in an environment that is aligned with the principle stress vector. We tested this idea by introducing grooves in the principal stress direction on the surface of an implant. This work thus analyzes the effect of stress transmission by a load at the proximal femur on the bone inside and near the grooves by using mechanical simulation in which groove angles can be changed on the implant surface. Coordinate data from the mechanical simulation of the combined bone/implant environment was verified against the coordinate data obtained by CT scans of actual canine bone. Results suggest that the tendency of stress transmission differs depending on the position and angle of the grooves and based on a vector diagram of the maximum and minimum principal stresses. The simulation was able to predict bone dynamics in vivo and enabled a best design of an implant to control the BAp/Col. alignment as an index of bone quality.

  9. Regenerative Surgical Treatment of Peri-implantitis

    ClinicalTrials.gov

    2015-07-16

    Failure of Dental Implant Due to Infection; Infection; Inflammation; Peri-implantitis; Bacterial Infections; Bleeding of Subgingival Space; Molecular Sequence Variation; Periodontal Diseases; Mouth Diseases

  10. A rationale for technology transfer

    NASA Technical Reports Server (NTRS)

    Gray, E. Z.

    1978-01-01

    Specific contributions of the NASA Technology Utilization Program are outlined, including: improved firefighting equipment, electrical implants for medical purposes, and improved methods of weather forecasting. Cooperation between NASA and other organizations in both the public and private sectors is stressed.

  11. Vestibular function and cochlear implant.

    PubMed

    Robard, Laetitia; Hitier, Martin; Lebas, Catherine; Moreau, Sylvain

    2015-03-01

    Vestibular lesions are found after cochlear implantation in 23-100 % of cases. The objectives of this study were to evaluate the vestibular function before and after implantation while focusing its feasibility. This prospective study included 35 patients, mean age 49 years. Each patient enjoyed a vestibular balance before and after implantation in a median period of 5 months compared to surgery. Vestibular evaluations were performed using vestibular-evoked myogenic potentials (VEMP) and videonystagmography. Before implantation, the VEMPs were bilateral in 73 % of cases. They are modified after implantation for 13 patients, including 12 missing or reduced potentials on implanted side (p = 0.0015). Caloric tests found themselves a significant decrease in the reflectivity of the ear implanted (p < 0.0001). Vestibular symptoms were independent of changes on vestibular tests. No relation was found between the occurrence of post-operative vestibular symptoms and the results of the vestibular investigations. However, the achievement of these exams is not easy especially for children and only part of the vestibule is tested. In conclusion, the vestibular assessments help to choose the side of implantation, assess the pre-operative vestibular condition and assess and locate vestibular lesions induced. Further tests should enable a complete vestibular assessment. PMID:24737055

  12. Cochlear Implants: More? And Better?

    ERIC Educational Resources Information Center

    Carroll, Cathryn

    1995-01-01

    Summarizes a discussion on cochlear implants from a National Institutes of Health conference. Reviews the cited benefits of the implants in children. Gives comments on research on the language performance of children who are deaf or hearing impaired in oral programs versus those in total communication programs, as well as dissenting opinions on…

  13. Immunology of Silicone Breast Implants

    Microsoft Academic Search

    Nir Kossovsky; Charles J. Freiman

    1994-01-01

    Understanding the immunology of silicone breast implants, at present, consists of reconciling an increasingly large body of data with an older, established, but otherwise unsubstantiated theory. Despite the variety of silicone breast implants, there are nevertheless certain phenomena that occur with all silicone gel-filled devices. Recent clinical findings suggest that in some patients, silicone will act as an adjuvant on

  14. Labyrinthectomy with cochlear implantation.

    PubMed

    Zwolan, T A; Shepard, N T; Niparko, J K

    1993-05-01

    Numerous reports indicate that the cochlea remains responsive to electrical stimulation following labyrinthectomy. We report a case of a 47-year-old woman with a severe to profound sensorineural hearing loss from birth, who developed episodic vertigo with symptoms suggestive of delayed onset endolymphatic hydrops. Following 8 months of failed medical and vestibular rehabilitation management, a right-sided labyrinthectomy combined with cochlear implantation was performed without complication. Postoperatively the patient was free of vertigo. Attempts to activate the patient's device between 4 to 12 weeks after surgery were unsuccessful as stimulation of the electrodes resulted in discomfort. However, all 20 electrodes elicited comfortable hearing sensations 16 weeks postsurgery. One year after the successful activation, the patient demonstrated improved sound awareness and speech recognition with the implant when compared with preoperative performance with a hearing aid. This case study suggests that electrical detection thresholds with prosthetic stimulation may be unstable in the recently labyrinthectomized ear but supports and extends prior observations of preserved cochlear responsiveness after labyrinthectomy. PMID:8372917

  15. Implantation of Vascular Grafts Lined with Genetically Modified Endothelial Cells

    NASA Astrophysics Data System (ADS)

    Wilson, James M.; Birinyi, Louis K.; Salomon, Robert N.; Libby, Peter; Callow, Allan D.; Mulligan, Richard C.

    1989-06-01

    The possibility of using the vascular endothelial cell as a target for gene replacement therapy was explored. Recombinant retroviruses were used to transduce the lacZ gene into endothelial cells harvested from mongrel dogs. Prosthetic vascular grafts seeded with the genetically modified cells were implanted as carotid interposition grafts into the dogs from which the original cells were harvested. Analysis of the graft 5 weeks after implantation revealed genetically modified endothelial cells lining the luminal surface of the graft. This technology could be used in the treatment of atherosclerosis disease and the design of new drug delivery systems.

  16. Ion implantation synthesized copper oxide-based resistive memory devices

    NASA Astrophysics Data System (ADS)

    Bishop, S. M.; Bakhru, H.; Novak, S. W.; Briggs, B. D.; Matyi, R. J.; Cady, N. C.

    2011-11-01

    Copper oxide resistive memory layers have been synthesized by ion implantation. Devices fabricated from off-stoichiometric Cu2O exhibited unipolar switching in forward/reverse bias without a forming voltage. The on-state conduction of these devices is likely dominated by a metallic filament, which ruptures via Joule heating to transition the device to the high resistance off-state. Technology scaling was achieved by oxygen implanting copper filled vias. The resulting via-based memory devices exhibited unipolar resistive switching down to 48 nm in diameter.

  17. Some considerations concerning cochlear implantation in IFACF-ORL

    PubMed Central

    Hainarosie, M; Zainea, V; Serban, S; Georgescu, MG; Hainarosie, R; Marinescu, A; Georgescu, G

    2014-01-01

    The article analyzes the patients who have received a cochlear implant at “Prof. Dr. Dorin Hociota” Institute of Phonoaudiology and Functional ENT Surgery, Bucharest, over a period of 13 years, from the beginning of this program in the year 2000. It presents the types of devices used, the particularities of the patients, the surgical techniques and the outcome, critically analyzing the complications encountered. The authors’ comments on the selection of patient protocol, surgical intraoperative challenges and cochlear implant technologies and capabilities are presented. PMID:25870683

  18. A Retrospective Analysis of Ruptured Breast Implants

    PubMed Central

    Baek, Woo Yeol; Lew, Dae Hyun

    2014-01-01

    Background Rupture is an important complication of breast implants. Before cohesive gel silicone implants, rupture rates of both saline and silicone breast implants were over 10%. Through an analysis of ruptured implants, we can determine the various factors related to ruptured implants. Methods We performed a retrospective review of 72 implants that were removed for implant rupture between 2005 and 2014 at a single institution. The following data were collected: type of implants (saline or silicone), duration of implantation, type of implant shell, degree of capsular contracture, associated symptoms, cause of rupture, diagnostic tools, and management. Results Forty-five Saline implants and 27 silicone implants were used. Rupture was diagnosed at a mean of 5.6 and 12 years after insertion of saline and silicone implants, respectively. There was no association between shell type and risk of rupture. Spontaneous was the most common reason for the rupture. Rupture management was implant change (39 case), microfat graft (2 case), removal only (14 case), and follow-up loss (17 case). Conclusions Saline implants have a shorter average duration of rupture, but diagnosis is easier and safer, leading to fewer complications. Previous-generation silicone implants required frequent follow-up observation, and it is recommended that they be changed to a cohesive gel implant before hidden rupture occurs. PMID:25396188

  19. Rapid thermal annealing of Be, Si, and Zn implanted GaAs using an ultrahigh power argon arc lamp

    Microsoft Academic Search

    K. Tabatabaie-Alavi; A. N. M. Masum Choudhury; C. G. Fonstad; J. C. Gelpey

    1983-01-01

    The use of a 100-kW water-walled dc argon lamp to anneal ion-implanted GaAs is reported. Annealing cycles of 3 and 10 s and peak temperatures from 950 to 1200 °C have been used to anneal Be, Si, and Zn implanted following representative implant schedules of technological importance. It is demonstrated that this technique is superior to conventional furnace anneal techniques

  20. Rapid thermal annealing of Be, Si, and Zn implanted GaAs using an ultrahigh power argon arc lamp

    Microsoft Academic Search

    K. Tabatabaie-Alavi; A. N. M. Masum Choudhury; C. G. Fonstad; J. C. Gelpey

    1983-01-01

    The use of a 100-kW water-walled dc argon lamp to anneal ion-implanted GaAs is reported. Annealing cycles of 3 and 10 s and peak temperatures from 950 to 1200 C have been used to anneal Be, Si, and Zn implanted following representative implant schedules of technological importance. It is demonstrated that this technique is superior to conventional furnace anneal techniques

  1. Ion implantation for high performance III-V JFETS and HFETS

    SciTech Connect

    Zolper, J.C.; Baca, A.G.; Sherwin, M.E.; Klem, J.F.

    1996-06-01

    Ion implantation has been an enabling technology for realizing many high performance electronic devices in III-V semiconductor materials. We report on advances in ion implantation processing for GaAs JFETs (joint field effect transistors), AlGaAs/GaAs HFETs (heterostructure field effect transistors), and InGaP or InAlP-barrier HFETs. The GaAs JFET has required the development of shallow p-type implants using Zn or Cd with junction depths down to 35 nm after the activation anneal. Implant activation and ionization issues for AlGaAs are reported along with those for InGaP and InAlP. A comprehensive treatment of Si-implant doping of AlGaAs is given based on donor ionization energies and conduction band density-of-states dependence on Al-composition. Si and Si+P implants in InGaP are shown to achieve higher electron concentrations than for similar implants in AlGaAs due to absence of the deep donor level. An optimized P co- implantation scheme in InGaP is shown to increase the implanted donor saturation level by 65%.

  2. Functional Apparent Moduli (FAMs) as Predictors of Oral Implant Osseointegration Dynamics

    PubMed Central

    Chang, Po-Chun; Seol, Yang-Jo; Kikuchi, Noboru; Goldstein, Steven A.; Giannobile, William V.

    2010-01-01

    At present, limited functional data exists regarding the application and use of biomechanical and imaging technologies for oral implant osseointegration assessment. The objective of this investigation was to determine the functional apparent moduli (FAMs) that could predict the dynamics of oral implant osseointegration. Using an in vivo dental implant osseous healing model, two FAMs, functional bone apparent modulus (FBAM) and composite tissue apparent modulus (FCAM), of the selected peri-implant structures were calculated via microcomputed tomography (micro-CT) and finite element (FE) simulations in order to support this concept. Results showed significant sensitivity between FAMs and micro-CT parameters, especially between bone mineral density and FBAM, while at extraction defect sites the strongest correlations existed between bone-implant contact and FCAM. Significant enhancement of FCAM indicated progressive functional repair during early osseointegration. Further, the resultant interfacial resistance was predicted by bone mineral content (BMC) and FBAM within a ~200 ?m peri-implant thickness, while the extraction defects gave zones of ~575 ?m and 200 ?m for BMC and FCAM, respectively. These results suggest that the function of dental implant support can be predicted from a peri-implant structural zone. We conclude that FAMs can be used to predict the dynamics of dental implant osseointegration in vivo. PMID:20524185

  3. Technologies Technologies

    E-print Network

    Sart, Remi

    .delbos@univ-bpclermont.fr UFR Sciences et Technologies Université Blaise Pascal 24 avenue des Landais BP 80026 63171 AUBIERE Sciences et Technologies Université Blaise Pascal 24 avenue des Landais BP 80026 63171 AUBIERE Cedex Tel Corpusculaire ­ IN2P3 UFR Sciences et Technologies Université Blaise Pascal 24 avenue des Landais BP 80026 63171

  4. Cochlear Implantation in Extraordinary Cases

    PubMed Central

    Çelenk, Fatih; Cevizci, Ra?it; Alt?nyay, ?enay; Bayaz?t, Y?ld?r?m Ahmet

    2015-01-01

    Background: Although cochlear implantation has been almost a standard otological procedure worldwide, it may still create a dilemma for the surgeon in some unusual instances such as Seckel syndrome, aural atresia and posterior fossa arachnoid cyst. Case Report: Three extraordinary cases of cochlear implantation were reported. The first case was a case of Seckel syndrome with a cardiac pacemaker due to complete atrioventricular block. The second case had posterior fossa arachnoid cyst that had retrosigmoid cyst removal and cochlear implantation simultaneously. The last case had cochlear implantation in the ear with congenital aural atresia. All cases could be implanted successfully with full electrode insertion and good audiological outcome. Delayed facial paralysis that occurred in the patient with arachnoid cyst resolved spontaneously. Conclusion: This study addressed the efficiency of cochlear implantation in cases of Seckel syndrome, complete atrioventricular block managed with cardiac pacemaker, congenital aural atresia and posterior fossa arachnoid cyst. In addition, the retrosigmoid approach and cochlear implantation can be performed simultaneously. PMID:26167347

  5. Wireless microsensor network solutions for neurological implantable devices

    NASA Astrophysics Data System (ADS)

    Abraham, Jose K.; Whitchurch, Ashwin; Varadan, Vijay K.

    2005-05-01

    The design and development of wireless mocrosensor network systems for the treatment of many degenerative as well as traumatic neurological disorders is presented in this paper. Due to the advances in micro and nano sensors and wireless systems, the biomedical sensors have the potential to revolutionize many areas in healthcare systems. The integration of nanodevices with neurons that are in communication with smart microsensor systems has great potential in the treatment of many neurodegenerative brain disorders. It is well established that patients suffering from either Parkinson"s disease (PD) or Epilepsy have benefited from the advantages of implantable devices in the neural pathways of the brain to alter the undesired signals thus restoring proper function. In addition, implantable devices have successfully blocked pain signals and controlled various pelvic muscles in patients with urinary and fecal incontinence. Even though the existing technology has made a tremendous impact on controlling the deleterious effects of disease, it is still in its infancy. This paper presents solutions of many problems of today's implantable and neural-electronic interface devices by combining nanowires and microelectronics with BioMEMS and applying them at cellular level for the development of a total wireless feedback control system. The only device that will actually be implanted in this research is the electrodes. All necessary controllers will be housed in accessories that are outside the body that communicate with the implanted electrodes through tiny inductively-coupled antennas. A Parkinson disease patient can just wear a hat-system close to the implantable neural probe so that the patient is free to move around, while the sensors continually monitor, record, transmit all vital information to health care specialist. In the event of a problem, the system provides an early warning to the patient while they are still mobile thus providing them the opportunity to react and trigger the feed back system or contact a point-of-care office that can remotely control the implantable system. The remote monitoring technology can be adaptable to EEG monitoring of children with epilepsy, implantable cardioverters/defibrillators, pacemakers, chronic pain management systems, treatment for sleep disorders, patients with implantable devices for diabetes. In addition, the development of a wireless neural electronics interface to detect, transmit and analyze neural signals could help patients with spinal injuries to regain some semblance of mobile activity.

  6. Emerging Synergy between Nanotechnology and Implantable Biosensors: A Review

    PubMed Central

    Vaddiraju, Santhisagar; Tomazos, Ioannis; Burgess, Diane J; Jain, Faquir C; Papadimitrakopoulos, Fotios

    2010-01-01

    The development of implantable biosensors for continuous monitoring of metabolites is an area of sustained scientific and technological interest. On the other hand, nanotechnology, a discipline which deals with the properties of materials at the nanoscale, is developing as a potent tool to enhance the performance of these biosensors. This article reviews the current state of implantable biosensors, highlighting the synergy between nanotechnology and sensor performance. Emphasis is placed on the electrochemical method of detection in light of its widespread usage and substantial nanotechnology-based improvements in various aspects of electrochemical biosensor performance. Finally, issues regarding toxicity and biocompatibility of nanomaterials, along with future prospects for the application of nanotechnology in implantable biosensors, are discussed. PMID:20042326

  7. Nitinol Surfaces for Implantation

    NASA Astrophysics Data System (ADS)

    Shabalovskaya, Svetlana; Rondelli, Gianni; Rettenmayr, Markus

    2009-08-01

    Nitinol, a group of nearly equiatomic Ni-Ti alloys, steadily conquers new areas of application. Because of the need to keep a low profile of miniature implant devices, and considering the lack of compatibility between Nitinol superelasticity and the mechanical properties of traditional coatings, bare surfaces are of interest. In this article, an overview of our studies of bare Nitinol surfaces is presented, and the performance of coated surfaces is outlined. Together dense and porous Nitinol offer a wide array of surface topographies, suitable for attachment and migration of biological cells and tissue ingrowth. Native Nitinol surface oxides vary from amorphous to crystalline and exhibit semiconducting properties associated with better blood compatibility. Nitinol surfaces are analyzed with regard to high and lasting nickel release in vitro. Surface oxide thickness and Nitinol intermetallic particulates are discussed in relation to corrosion resistance and mechanical performance of the material.

  8. Introduction to cochlear implants Philipos C. Loizou

    E-print Network

    Allen, Jont

    1 Introduction to cochlear implants Philipos C. Loizou For centuries, people believed that only speech. Today, a prosthetic device, called cochlear implant, can be implanted in the inner ear and can to the development of a successful cochlear implant. After all, it is important to know how a normal auditory system

  9. Cochlear Implants in Prelingually Deaf Children.

    ERIC Educational Resources Information Center

    Rose, Darrell E.; And Others

    1996-01-01

    Survey respondents from 45 residential and day schools for the deaf found that, of 151 prelingually deaf children who had received cochlear implants, 71 were no longer using the implant. Numerous comments by respondents indicated their discouragement with the results of the implants. Children still using the implants were concentrated in three…

  10. Implantable biomedical devices: Wireless powering and communication

    Microsoft Academic Search

    Anatoly Yakovlev; Sanghoek Kim; Ada Poon

    2012-01-01

    In recent years, there has been major progress on implantable biomedical systems that support most of the functionalities of wireless implantable devices. Nevertheless, these devices remain mostly restricted to research, in part due to limited miniaturization, power supply constraints, and lack of a reliable interface between implants and external devices. This article provides a tutorial on the design of implantable

  11. Boron and nitrogen implantation of steels

    Microsoft Academic Search

    K. T. Kern; K. C. Walter; A. J. Griffin; Y. Lu; M. Nastasi; W. K. Scarborough; J. R. Tesmer; S. Fayeulle

    1997-01-01

    Samples of four steels with varying chromium content were implanted with boron and seperately with nitrogen. Implantation energy was 75 keV in all cases. Implantation profiles were modeled using TRIM and determined experimentally by ion beam analysis. Boron ion sources leading to improved ion beams will be discussed. Material characterization included tribology and nano-indentation. Implanted materials showed improvements in wear

  12. Soft tissue surgery for implants.

    PubMed

    Batal, Hussam; Yavari, Amir; Mehra, Pushkar

    2015-04-01

    Adequate quality and quantity of soft tissue plays an integral part in the esthetic outcome of dental implants. Adequate band of attached tissue decreases the incidence of mucositis and improves hygiene around implants. This article discusses a variety of techniques for soft tissue augmentation. Soft tissue grafting can be achieved at various stages of implant therapy. Epithelial connective tissue grafts are commonly used to increase the band of attached tissue. Subepithelial connective tissue grafts are great for increasing soft tissue thickness and improving the gingival biotype. PMID:25835804

  13. Properties of implanted PET by W ion using MEVVA implantation

    Microsoft Academic Search

    Wu. Yuguang; Zhang Tonghe; Liu Andong; Zhang Xu; Zhou Gu

    2003-01-01

    Polyethylene terephthalane (PET) has been modified with W ions from a metal vapour arc source (MEVVA). W ions were implanted at 136keV to doses ranging from 5×1015 to 2×1017\\/cm2. The surface of the implanted PET darkened with increasing ion dose, when the metal ion dose is greater than 1×1017cm?2 the colour changed to metallic bright. The surface resistance obviously decreases

  14. Tribological properties of nitrogen implanted and boron implanted steels

    Microsoft Academic Search

    K. T. Kern; K. C. Walter; A. J. Jr. Griffin; H. Kung; Y. Lu; M. Nastasi; J. R. Tesmer; S. Fayeulle

    1996-01-01

    Samples of a steel with high chrome content was implanted separately with 75 keV nitrogen ions and with 75 keV boron ions. Implanted doses of each ion species were 2-, 4-, and 8 à 10¹⁷\\/cm². Retained doses were measured using resonant non-Rutherford Backscattering Spectrometry. Tribological properties were determined using a pin-on-disk test with a 6-mm diameter ruby pin with a

  15. Evaluation of the Edge Crack Torsion (ECT) Test for Mode 3 Interlaminar Fracture Toughness of Laminated Composites

    NASA Technical Reports Server (NTRS)

    Li, Jian; Lee, Edward W.; OBrien, T. Kevin; Lee, Shaw Ming

    1996-01-01

    An analytical and experimental investigation was carried out on G40-800/R6376 graphite epoxy laminates to evaluate the Edge Crack Torsion (ECT) test as a candidate for a standard Mode 3 interlaminar fracture toughness test for laminated composites. The ECT test consists of a (90/(+/- 45)(sub 3)/(+/- 45)(sub 3)/90))(sub s) laminate with a delamination introduced by a non-adhesive film at the mid-plane along one edge and loaded in a special fixture to create torsion along the length of the laminate. Dye penetrate enhanced X-radiograph of failed specimens revealed that the delamination initiated at the middle of the specimen length and propagated in a self similar manner along the laminate mid-plane. A three-dimensional finite element analysis was performed that indicated that a pure Mode 3 delamination exists at the middle of specimen length away from both ends. At the ends near the loading point a small Mode 2 component exists. However, the magnitude of this Mode 2 strain energy release rate at the loading point is small compared to the magnitude of Mode 3 component in the mid-section of the specimen. Hence, the ECT test yielded the desired Mode 3 delamination. The Mode 3 fracture toughness was obtained from a compliance calibration method and was in good agreement with the finite element results. Mode 2 End-Notched Flexure (ENF) tests and Mode 1 Double Cantilever Beam (DCB) tests were also performed for the same composite material. The Mode 1 fracture toughness was much smaller than both the Mode 2 and Mode 3 fracture toughness. The Mode 2 fracture toughness was found to be 75% of the Mode 3 fracture toughness.

  16. MSE2311 : Sries chronologiques (6 ECTS) http://www.ufr-mi.u-bordeaux.fr/~yger/MSE2311_Series_chronologiqu... 1 sur 2 15/07/2008 14:50

    E-print Network

    Yger, Alain

    MSE2311 : Séries chronologiques (6 ECTS) http://www.ufr-mi.u-bordeaux.fr/~yger/MSE2311_Series_chronologiqu : Séries chronologiques (6 ECTS) http://www.ufr-mi.u-bordeaux.fr/~yger/MSE2311_Series_chronologiqu... 2 sur Previous: MSE2302 : Plans d'expériences MSE2311 : Séries chronologiques (6 ECTS) Code apogée MSE2311

  17. Surface modification by negative-ion implantation

    Microsoft Academic Search

    Junzo Ishikawa; Hiroshi Tsuji; Yasuhito Gotoh

    2009-01-01

    We have developed a negative-ion implantation technique for surface modification of materials together with the development of high-intensity negative-ion sources and negative-ion implanters. In the negative-ion implantation, we have the advantage of a nearly “charge-up-free” property for the implanted surface of insulators or insulated materials. The charging voltage on the implanted surface is no greater than plus or minus a

  18. Foreign Body Reaction to Cochlear Implant

    Microsoft Academic Search

    Jona Kronenberg; Michael Wolf; Lela Migirov; Yisgav Shapira; Sarit Aviel-Ronen; Minka Hildesheimer

    2001-01-01

    Two cases of foreign body reaction to a cochlear implant are described. A Nucleus-22 cochlear implant encased in silicone rubber was implanted in both. The first is a 66-year-old patient with idiopathic hearing loss. A year following the procedure, a fistulous tract developed over the implant with a typical histological foreign body reaction. The implant was removed and another Nucleus-22

  19. Systematic analysis and experiment of inductive coupling and induced voltage for inductively coupled wireless implantable neurostimulator application

    Microsoft Academic Search

    Ning Xue; Sung-Hoon Cho; Sung-Pil Chang; Jeong-Bong Lee

    2012-01-01

    The main strategy for wireless power transfer to implantable devices is to use inductive coupling technology. The induced voltage of implanted devices highly depends on factors such as mutual inductance between the external transmitter coil and the receiver coil, quality factor of the receiver circuit and operation frequency. In this paper, the mutual inductance under a variety of geometries of

  20. Chromosomal localization of the human ECT2 proto-oncogene to 3q26.1 {yields} q26.2 by somatic cell analyses and fluorescence in situ hybridization

    SciTech Connect

    Takai, Setsuo; Yamada, Kiyomi [International Medical Center of Japan, Tokyo (Japan)] [International Medical Center of Japan, Tokyo (Japan); Long, J.E. [National Cancer Institute, Bethesda, MD (United States)] [and others] [National Cancer Institute, Bethesda, MD (United States); and others

    1995-05-01

    The mouse ect2 oncogene was identified in a search of mitogenic signal transducers using a novel expression cloning strategy. In this system, the introduction of an appropriate expression-cDNA library prepared from the mRNA of one cell type into another can result in the morphological transformation of the recipient cells. The predicted Ect2 protein has sequence similarity within a central core of 255 amino acids to the products of the breakpoint-cluster gene, bcr, the yeast cell cycle gene, CDC24, the dbl and vav oncogenes, and the RasGrf gene. Baculovirus-expressed Ect2 protein shows specific binding to Rho and Rac proteins, indicating that Ect2 is a new member of transforming proteins that can interact with Rho-like proteins of the Ras superfamily. The ect2 foci exhibit an unusual stellate morphology and are capable of forming tumors when subcutaneously inoculated in nude mice. These results indicate that the ect2 gene acts as an oncogene. To investigate the involvement of the ect2 in human tumors, the authors isolated the human homolog, ECT2, of mouse ect2 and determined its chromosomal localization. 13 refs., 1 fig.

  1. ANTIARRHYTHMICS VERSUS IMPLANTABLE DEFIBRILLATORS (AVID)

    EPA Science Inventory

    Evaluates whether use of an implantable cardiac defibrillator (ICD) results in reduction in total mortality, when compared with conventional pharmacological therapy, in patients resuscitated from sudden cardiac death who are otherwise at very high risk of mortality from arrhythmi...

  2. Evaluation of Bone Fixation Implants

    E-print Network

    Perkins, Luke 1990-

    2012-12-10

    was analyzed using light interferometric technique. Potentiodynamic polarization analysis was performed to evaluate corrosive behavior before and after implanting. Scratch tests were conducted to evaluate wear resistance and the microstructure was analyzed...

  3. [Surgical technique in cochlear implantation].

    PubMed

    Praetorius, M; Staecker, H; Plinkert, P K

    2009-07-01

    The cochlear implant (CI) has become a standard option for treating prelingually deaf children. But postlingual late deafness in adults is becoming increasingly common. In addition, hybrid implantation with a CI and a hearing aid in the same ear has come into focus, which demands a soft insertion technique that spares the apical parts of the cochlea. Also, the chorda tympani should be saved, especially in bilateral implantations, which are gaining importance because improved speech discrimination in noisy conditions is seen as proven today. Control of the electrode position intraoperatively with intraoperative computed tomography can further increase the safety and reliability of the position. The position and length of the skin incision is a more aesthetic issue. Future developments will include fully implantable CIs and navigation-assisted, minimally invasive drilling of a hole from the surface of the skull into the cochlea. Bioactive, neurotrophic-drug-releasing electrode designs for improved and sustainable connectivity to the neurons may become applicable. PMID:19554272

  4. Cochlear implants in young children.

    PubMed

    Niparko, John K; Blankenhorn, Rebecca

    2003-01-01

    The cochlear implant is best characterized as a device that provides access to the sound environment. The device enables the hearing pathway to respond to environmental and speech sounds, providing informational cues from the surroundings and from others that may escape visual detection. As the developmental effects of a profound hearing loss are multiple, cochlear implants have been applied to ever younger children in an attempt to promote a more normal level of developmental learning through audition. In deafness, transducer elements of the inner ear fail to trigger auditory nerve afferent nerves in the presence of sound input. However, large reserves of afferent fibers exist even in the auditory nerve of a profoundly deaf patient. Furthermore, these nerve fibers retain the ability to respond to prosthetic activation. Through developmental learning in the early, formative years, auditory centers of the brain appear capable of processing information from the implant to provide speech comprehension and oral language development. Multichannel implants have replaced original single channel designs. multichannel devices enable larger percentages of recipients to recognize the spoken word without visual cues because they provide spectral information in addition to temporal and intensity cues. Testing under conditions of auditory (implant)-only input reveals significant open-set speech understanding capabilities in more than 75% of children after three years of device use. The benefit provided by implants may vary with a number of conditions including: hearing history, age of deafness onset, age at implantation, etiology of deafness, linguistic abilities, and the presence of a motivated system of support of oral language development. Patient variables should be given individual consideration in judging candidacy for a cochlear implant and in planning rehabilitative and education services after surgery and activation of the device. PMID:14648819

  5. Implant stategies for Littlefield Feedyard 

    E-print Network

    Turner, John Sutton

    1995-01-01

    IMPLANT STRATEGIES FOR LITTLEFIELD FEEDYARD PROFESSIONAL PAPER May, 1995 John Sutton Turner Record of Study IMPLANT STRATEGIES FOR LITTLEFIELD FEEDYARD A PROFESSIONAL PAPER by John Sutton Turner Submitted to the College of Agriculture... A PROFESSIONAL PAPER by John Sutton Turner Approved as to style and content by: Dr. W. L. Mies (Chair, Advisory Committee) Dr. J W. Turner (Committee Member) Dr A Larke, Jr (Committee mber) May, 1995 "of graduation Abstract The objective...

  6. Body Implanted Medical Device Communications

    NASA Astrophysics Data System (ADS)

    Yazdandoost, Kamya Yekeh; Kohno, Ryuji

    The medical care day by day and more and more is associated with and reliant upon concepts and advances of electronics and electromagnetics. Numerous medical devices are implanted in the body for medical use. Tissue implanted devices are of great interest for wireless medical applications due to the promising of different clinical usage to promote a patient independence. It can be used in hospitals, health care facilities and home to transmit patient measurement data, such as pulse and respiration rates to a nearby receiver, permitting greater patient mobility and increased comfort. As this service permits remote monitoring of several patients simultaneously it could also potentially decrease health care costs. Advancement in radio frequency communications and miniaturization of bioelectronics are supporting medical implant applications. A central component of wireless implanted device is an antenna and there are several issues to consider when designing an in-body antenna, including power consumption, size, frequency, biocompatibility and the unique RF transmission challenges posed by the human body. The radiation characteristics of such devices are important in terms of both safety and performance. The implanted antenna and human body as a medium for wireless communication are discussed over Medical Implant Communications Service (MICS) band in the frequency range of 402-405MHz.

  7. Auditory Midbrain Implant: A Review

    PubMed Central

    Lim, Hubert H.; Lenarz, Minoo; Lenarz, Thomas

    2009-01-01

    The auditory midbrain implant (AMI) is a new hearing prosthesis designed for stimulation of the inferior colliculus in deaf patients who cannot sufficiently benefit from cochlear implants. The authors have begun clinical trials in which five patients have been implanted with a single shank AMI array (20 electrodes). The goal of this review is to summarize the development and research that has led to the translation of the AMI from a concept into the first patients. This study presents the rationale and design concept for the AMI as well a summary of the animal safety and feasibility studies that were required for clinical approval. The authors also present the initial surgical, psychophysical, and speech results from the first three implanted patients. Overall, the results have been encouraging in terms of the safety and functionality of the implant. All patients obtain improvements in hearing capabilities on a daily basis. However, performance varies dramatically across patients depending on the implant location within the midbrain with the best performer still not able to achieve open set speech perception without lip-reading cues. Stimulation of the auditory midbrain provides a wide range of level, spectral, and temporal cues, all of which are important for speech understanding, but they do not appear to sufficiently fuse together to enable open set speech perception with the currently used stimulation strategies. Finally, several issues and hypotheses for why current patients obtain limited speech perception along with several feasible solutions for improving AMI implementation are presented. PMID:19762428

  8. Optima XE Single Wafer High Energy Ion Implanter

    SciTech Connect

    Satoh, Shu; Ferrara, Joseph; Bell, Edward; Patel, Shital; Sieradzki, Manny [Axcelis Technologies, Inc. 108 Cherry Hill Drive, Beverly, MA 01915 (United States)

    2008-11-03

    The Optima XE is the first production worthy single wafer high energy implanter. The new system combines a state-of-art single wafer endstation capable of throughputs in excess of 400 wafers/hour with a production-proven RF linear accelerator technology. Axcelis has been evolving and refining RF Linac technology since the introduction of the NV1000 in 1986. The Optima XE provides production worthy beam currents up to energies of 1.2 MeV for P{sup +}, 2.9 MeV for P{sup ++}, and 1.5 MeV for B{sup +}. Energies as low as 10 keV and tilt angles as high as 45 degrees are also available., allowing the implanter to be used for a wide variety of traditional medium current implants to ensure high equipment utilization. The single wafer endstation provides precise implant angle control across wafer and wafer to wafer. In addition, Optima XE's unique dose control system allows compensation of photoresist outgassing effects without relying on traditional pressure-based methods. We describe the specific features, angle control and dosimetry of the Optima XE and their applications in addressing the ever-tightening demands for more precise process controls and higher productivity.

  9. 21 CFR 886.3300 - Absorbable implant (scleral buckling method).

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...false Absorbable implant (scleral buckling method). 886.3300 Section...3300 Absorbable implant (scleral buckling method). (a) Identification. An absorbable implant (scleral buckling method) is a device intended...

  10. 21 CFR 886.3300 - Absorbable implant (scleral buckling method).

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...false Absorbable implant (scleral buckling method). 886.3300 Section...3300 Absorbable implant (scleral buckling method). (a) Identification. An absorbable implant (scleral buckling method) is a device intended...

  11. 21 CFR 886.3300 - Absorbable implant (scleral buckling method).

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...false Absorbable implant (scleral buckling method). 886.3300 Section...3300 Absorbable implant (scleral buckling method). (a) Identification. An absorbable implant (scleral buckling method) is a device intended...

  12. 21 CFR 886.3300 - Absorbable implant (scleral buckling method).

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...false Absorbable implant (scleral buckling method). 886.3300 Section...3300 Absorbable implant (scleral buckling method). (a) Identification. An absorbable implant (scleral buckling method) is a device intended...

  13. 21 CFR 872.3645 - Subperiosteal implant material.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... false Subperiosteal implant material. 872.3645...CONTINUED) MEDICAL DEVICES DENTAL DEVICES Prosthetic Devices...872.3645 Subperiosteal implant material. (a) Identification. Subperiosteal implant material is a...

  14. 21 CFR 872.3645 - Subperiosteal implant material.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... false Subperiosteal implant material. 872.3645...CONTINUED) MEDICAL DEVICES DENTAL DEVICES Prosthetic Devices...872.3645 Subperiosteal implant material. (a) Identification. Subperiosteal implant material is a...

  15. 21 CFR 872.3645 - Subperiosteal implant material.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... false Subperiosteal implant material. 872.3645...CONTINUED) MEDICAL DEVICES DENTAL DEVICES Prosthetic Devices...872.3645 Subperiosteal implant material. (a) Identification. Subperiosteal implant material is a...

  16. 21 CFR 872.3645 - Subperiosteal implant material.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... false Subperiosteal implant material. 872.3645...CONTINUED) MEDICAL DEVICES DENTAL DEVICES Prosthetic Devices...872.3645 Subperiosteal implant material. (a) Identification. Subperiosteal implant material is a...

  17. 21 CFR 872.3645 - Subperiosteal implant material.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... false Subperiosteal implant material. 872.3645...CONTINUED) MEDICAL DEVICES DENTAL DEVICES Prosthetic Devices...872.3645 Subperiosteal implant material. (a) Identification. Subperiosteal implant material is a...

  18. School of Computer Science and Statistics ECT Module Descriptor 2011-12

    E-print Network

    O'Mahony, Donal E.

    of the business and social impacts of contemporary developments in information systems and technology. To enable4500 Module Title Strategic Information Systems Pre-requisites Information Systems and Technology IS planning; · IS project management; · e-Government; · e-Democracy; · The information society; · e-Business

  19. A living thick nanofibrous implant bifunctionalized with active growth factor and stem cells for bone regeneration

    PubMed Central

    Eap, Sandy; Keller, Laetitia; Schiavi, Jessica; Huck, Olivier; Jacomine, Leandro; Fioretti, Florence; Gauthier, Christian; Sebastian, Victor; Schwinté, Pascale; Benkirane-Jessel, Nadia

    2015-01-01

    New-generation implants focus on robust, durable, and rapid tissue regeneration to shorten recovery times and decrease risks of postoperative complications for patients. Herein, we describe a new-generation thick nanofibrous implant functionalized with active containers of growth factors and stem cells for regenerative nanomedicine. A thick electrospun poly(?-caprolactone) nanofibrous implant (from 700 ?m to 1 cm thick) was functionalized with chitosan and bone morphogenetic protein BMP-7 as growth factor using layer-by-layer technology, producing fish scale-like chitosan/BMP-7 nanoreservoirs. This extracellular matrix-mimicking scaffold enabled in vitro colonization and bone regeneration by human primary osteoblasts, as shown by expression of osteocalcin, osteopontin, and bone sialoprotein (BSPII), 21 days after seeding. In vivo implantation in mouse calvaria defects showed significantly more newly mineralized extracellular matrix in the functionalized implant compared to a bare scaffold after 30 days’ implantation, as shown by histological scanning electron microscopy/energy dispersive X-ray microscopy study and calcein injection. We have as well bifunctionalized our BMP-7 therapeutic implant by adding human mesenchymal stem cells (hMSCs). The activity of this BMP-7-functionalized implant was again further enhanced by the addition of hMSCs to the implant (living materials), in vivo, as demonstrated by the analysis of new bone formation and calcification after 30 days’ implantation in mice with calvaria defects. Therefore, implants functionalized with BMP-7 nanocontainers associated with hMSCs can act as an accelerator of in vivo bone mineralization and regeneration. PMID:25709432

  20. FISH for Pre-implantation Genetic Diagnosis

    PubMed Central

    Scriven, Paul N.; Kirby, Toby L.; Ogilvie, Caroline Mackie

    2011-01-01

    Pre-implantation genetic diagnosis (PGD) is an established alternative to pre-natal diagnosis, and involves selecting pre-implantation embryos from a cohort generated by assisted reproduction technology (ART). This selection may be required because of familial monogenic disease (e.g. cystic fibrosis), or because one partner carries a chromosome rearrangement (e.g. a two-way reciprocal translocation). PGD is available for couples who have had previous affected children, and/or in the case of chromosome rearrangements, recurrent miscarriages, or infertility. Oocytes aspirated following ovarian stimulation are fertilized by in vitro immersion in semen (IVF) or by intracytoplasmic injection of an individual spermatozoon (ICSI). Pre-implantation cleavage-stage embryos are biopsied, usually by the removal of a single cell on day 3 post-fertilization, and the biopsied cell is tested to establish the genetic status of the embryo. Fluorescence in situ hybridization (FISH) on the fixed nuclei of biopsied cells with target-specific DNA probes is the technique of choice to detect chromosome imbalance associated with chromosome rearrangements, and to select female embryos in families with X-linked disease for which there is no mutation-specific test. FISH has also been used to screen embryos for spontaneous chromosome aneuploidy (also known as PGS or PGD-AS) in order to try and improve the efficiency of assisted reproduction; however, the predictive value of this test using the spreading and FISH technique described here is likely to be unacceptably low in most people's hands and it is not recommended for routine clinical use. We describe the selection of suitable probes for single-cell FISH, spreading techniques for blastomere nuclei, and in situ hybridization and signal scoring, applied to PGD in a clinical setting. PMID:21403624

  1. [Biodeterioration and corrosion of metallic implants and prostheses].

    PubMed

    López, G D

    1993-01-01

    The use of surgical implants and prosthetic devices to replace the original function of different components of the human biological system is a well established tradition in the history of medicine. Currently, one of the most prevalent points of view in dealing with this subject, is that of biocompatibility of materials of construction and methods of fabrication of these devices, in order to avoid negative impacts on the patient due to failure of implants through degradation mechanisms such as corrosion. This article presents a current general review of the relationship between biocompatibility and deterioration of metallic implants and prosthetic devices, emphasizing the specific forms that corrosion adopts in biological media. The historical perspective shows the consolidation of a tendency towards a more systematic study of these phenomena in recent years, as opposed to trial and error practices that used to be common before the third decade of this century. The understanding of interactions between implants and biological tissue, thus led to some of the most promising current techniques, such as the use of powder metallurgy components to optimize skeletal fixation of implants by means of interstitial bone growth into porous metallic surfaces. The review of metals and alloys currently used for the fabrication of implants shows the amplitude of available technological alternatives, as well as the multiple criteria required to make a good selection for each specific case. Applications and pros and cons of stainless steel, Cr, Ni, Co and Ti alloys, and tantalum are briefly discussed. The introduction to basic concepts of corrosion, serves as a basis for the description of the typical forms that these phenomena adopt in biological media, including pitting, crevice corrosion, fatigue-corrosion, stress corrosion, fretting corrosion, galvanic corrosion, and intergranular corrosion. This review shows that the study of interactions between biological media and metallic implants has become a well established and specific field of science. As a result of this conclusion, an interdisciplinary treatment of the subject of biodeterioration of metallic implants and prosthetic devices is proposed. In practical terms, this proposal can be understood as the integration of an expert in materials science and engineering to the medical team. Thus, quality and reliability of the implant, as well as maximization of its useful life, would be achieved through the implementation of technical specifications, accepted standards, and pertinent testing as recommended by the above mentioned expert, who will be the person of the team more able to grasp the novelties that the dynamic field of biomaterials constantly offers. PMID:8114635

  2. Effects of oxygen ion implantation in spray-pyrolyzed ZnO thin films

    NASA Astrophysics Data System (ADS)

    Vijayakumar, K. P.; Ratheesh Kumar, P. M.; Sudha Kartha, C.; Wilson, K. C.; Singh, F.; Nair, K. G. M.; Kashiwaba, Y.

    2006-04-01

    ZnO thin films, prepared using the chemical spray pyrolysis technique, were implanted using 100 keV O+ ions. Both pristine and ion-implanted samples were characterized using X-ray diffraction, optical absorption, electrical resistivity measurements, thermally stimulated current measurements and photoluminescence. Samples retained their crystallinity even after irradiation at a fluence of 1015 ions/cm2. However, at a still higher fluence of 2 × 1016 ions/cm2, the films became totally amorphous. The optical absorption edge remained unaffected by implantation and optical absorption spectra indicated two levels at 460 and 510 nm. These were attributed to defect levels corresponding to zinc vacancies (VZn) and oxygen antisites (OZn), respectively. Pristine samples had a broad photoluminescence emission centred at 517 nm, which was depleted on implantation. In the case of implanted samples, two additional emissions appeared at 425 and 590 nm. These levels were identified as due to zinc vacancies (VZn) and oxygen vacancies (VO), respectively. The electrical resistivity of implanted samples was much higher than that of pristine, while photosensitivity decreased to a very low value on implantation. This can be utilized in semiconductor device technology for interdevice isolation. Hall measurements showed a marked decrease in mobility due to ion implantation, while carrier concentration slightly increased.

  3. Oxidation inhibiting properties of Si3N4-layers produced by ion implantation

    NASA Astrophysics Data System (ADS)

    Ramin, M.; Ryssel, H.; Kranz, H.

    1980-08-01

    The implantation of nitrogen into silicon to produce Si3N4 layers was investigated to find an alternative to CVD-Si3N4 layers used in ISOPLANAR-and LOCOS-technology. The technological properties of the implanted Si3N4 layers in respect to oxidation inhibition and etching are comparable or superior to CVD-Si3N4 layers. The implanted layers are more resistent against oxidation for nitrogen doses of 2.4×1017 cm-2 at 30keV. The etching behavior is comparable for both types of Si3N4-layers. In the implanted layers no pinholes are found and threre is no formation of a bird's beak, as is well known in the case of CVD-nitride.

  4. 'Fast-implantable' aortic valve implantation and concomitant mitral procedures.

    PubMed

    Ferrari, Enrico; Siniscalchi, Giuseppe; Marinakis, Sotirios; Berdajs, Denis; von Segesser, Ludwig

    2014-10-01

    Concomitant aortic and mitral valve replacement or concomitant aortic valve replacement and mitral repair can be a challenge for the cardiac surgeon: in particular, because of their structure and design, two bioprosthetic heart valves or an aortic valve prosthesis and a rigid mitral ring can interfere at the level of the mitroaortic junction. Therefore, when a mitral bioprosthesis or a rigid mitral ring is already in place and a surgical aortic valve replacement becomes necessary, or when older high-risk patients require concomitant mitral and aortic procedures, the new 'fast-implantable' aortic valve system (Intuity valve, Edwards Lifesciences, Irvine, CA, USA) can represent a smart alternative to standard aortic bioprosthesis. Unfortunately, this is still controversial (risk of interference). However, transcatheter aortic valve replacements have been performed in patients with previously implanted mitral valves or mitral rings. Interestingly, we learned that there is no interference (or not significant interference) among the standard valve and the stent valve. Consequently, we can assume that a fast-implantable valve can also be safely placed next to a biological mitral valve or next to a rigid mitral ring without risks of distortion, malpositioning, high gradient or paravalvular leak. This paper describes two cases: a concomitant Intuity aortic valve and bioprosthetic mitral valve implantation and a concomitant Intuity aortic valve and mitral ring implantation. PMID:25015540

  5. Implantable FES Stimulation Systems: What is Needed?

    PubMed

    Troyk, P R; Donaldson, N de N

    2001-10-01

    Since their initial development, the performance gains in functional electrical stimulation (FES) systems have been modest. Conceptually, the replacement of normal neural function by artificial electronic systems is attractive, considering the continued technologic advancements in electronics, communication, and control. It is likely that efficacious FES systems will require complete implantation and activation of large numbers of motor units. One approach is to develop a neural interface that has a one-to-one relationship between stimulating electrodes and lower motor neurons. While technology may offer solutions to the design of miniaturized implantable stimulators, the high-density neural interface remains more elusive. During the past 20 years, research in the stimulation of peripheral motor systems has been primarily constrained by progress in two areas of research: strategies for the control of paralyzed muscle and sophistication of implantable stimulation systems. Often, a debate concerning which of these two areas is a "critical path" element yields no strategic ideas. It has been stated that a need must be demonstrated for a specific number of electrode channels before it is warranted to invest effort into the engineering of implantable systems that are capable of driving large numbers of electrodes. Indeed it is a logical approach to problem solving that the need should drive the development of function. Even study sections, in review of FES grant applications, often resort to this logic. In our opinion, when applied to FES, this argument is often fallacious and ignores the reality that research frequently requires that a threshold of experimental methodology be reached before any meaningful work can be accomplished. Practical trials of stimulation control strategies, long-term patient acceptance, and achievable function for FES systems cannot begin without the capability of stimulation. And, in order to determine whether or not stimulating large numbers of muscle groups can lead to more natural control of movement, suitable stimulation hardware must first exist, and be reliable. In the specific case of lower extremity FES research, it is likely that without a quantum advance in technologic capabilities, the practical utility of FES systems will continue to only be marginally close to normal function. To reach the level of being considered a routine treatment for spinal cord injury, FES systems should be able to offer improved functionality, ease of use, and near-equal reliability, compared to wheelchairs. At present, no FES systems attain this combination. The functional reliability of FES systems must approach 100%. As a trivial example, consider that for a standing, or walking, system, the perspectives of bioengineers and users may be quite different. While an engineer might be pleased to design a system that functions, as intended, 99% of the time, if a user falls down 1 time out of every 100, this is likely to be unacceptable. The minimal threshold of functional utility for FES systems is unclear, and will not be addressed here. Rather, we consider the issues of what features and capabilities are desirable for next generation implantable systems, and to what degree these desires approach engineering feasibility. PMID:22151723

  6. Novel implant for transcervical sterilization.

    PubMed

    Rehan, Muhammad; Coleman, James; Olabi, Abdul Ghani

    2010-08-01

    Compared to laparoscopic surgery for interval tubal sterilization, the transcervical approach is an effective method of female sterilization which obviates the requirement of general anesthesia and surgical incision. However, current methods of transcervical sterilization are unable to provide an instant occlusion. This paper focuses on the design, development and testing of a novel implant (James E., Coleman, Christy Cummins, 2009. Anastomosis Devices and Method. US Patent 20090105733A1) to achieve instant permanent female sterilization via the transcervical approach. The implant is designed to be deployed under hysteroscopic visualization into the ostium of the fallopian tube and relies on instant mechanical occlusion. The implant includes two sets of wings that penetrate into the ostium and uterine muscle tissue and trap the tissue in between thus plugging the entrance of the fallopian tube. In order to design the shape of implant wings and to investigate the mechanical behavior of the implant, a three-dimensional (3D) model was developed and Finite Element Method (FEM) was used for simulations. The implant was validated by a number of successful deployments in bench testing, animal tissue and explanted human uteri. During the deployments in animal tissue and explanted uteri, it was observed that the two sets of wings completely trapped the tissue in between and the hydraulic pressure testing of the explanted uteri using saline solution and methylene blue proved the instant occlusion of the fallopian tubes. Initial results suggest that this novel implant provides a safe and effective method of female sterilization. Further development work is ongoing in preparation for "first-in-man" clinical trials. PMID:20547383

  7. Maximizing Technology for Children with Hearing Loss

    E-print Network

    O'Toole, Alice J.

    Systems, and Cochlear Implants Linda M Thibodeau, Ph.D. Professor University of Texas at Dallas Callier SYSTEMS WITH COCHLEAR IMPLANTS 3G Speech Processor with Phonak MLxS FM Receiver #12;2/7/2012 6 Demo of CI2/7/2012 1 Maximizing Technology for Children with Hearing Loss: Verification of Hearing Aids, FM

  8. A high reliability CMOS implantable interface for wireless neural recording microsystem

    Microsoft Academic Search

    Hongge Li; Youguang Zhang

    2008-01-01

    A novel wireless implantable microsystem using a high-reliability digital technology is proposed for recording the hybrid neural signal. In order to enhance the neural recording intactness, we employ a kind of high-reliability design architecture, which includes a self-check circuit and a transmitter channel error check circuit. The proposed high-reliability structure can identify possible faults in any implantable interface. A dynamical

  9. Indium channel implant for improved short-channel behavior of submicrometer NMOSFETs

    Microsoft Academic Search

    G. G. Shahidi; Bijan Davari; Thomas J. Bucelot; P. A. Ronsheim; P. J. Coane; S. Pollack; C. R. Blair; B. Clark; Howard H. Hansen

    1993-01-01

    Indium has been used as an alternative channel implant in submicrometer-channel Si MOSFETs in order to obtain highly nonuniform channel doping. Superior device characteristics have been obtained down to 0.17-?m channel length. The device characteristics have been compared to those of uniform boron-implanted short-channel MOSFETs used in a 0.25-?m CMOS technology. Results indicate that NMOSFETs with nonuniform channel doping obtained

  10. Manufacturability of fully ion implanted planer-doped-barrier diodes in GaAs

    Microsoft Academic Search

    R. Gwilliam; Y. Y. Wang; M. J. Kelly; M. J. Kearney

    2005-01-01

    Given the superior control of ion implantation over dopant incorporation during epitaxy, in addition to the throughput and hence cost advantages, we have attempted the design and fabrication of a GaAs planar-doped-barrier diode with pre-specified electrical properties, using a fully ion implanted fabrication technology. The process requirements for such a device are the stringent control of both the dopant depth

  11. Anaesthetic management of transcatheter aortic valve implantation.

    PubMed

    Franco, Annalisa; Gerli, Chiara; Ruggeri, Laura; Monaco, Fabrizio

    2012-01-01

    Transcatheter aortic valve implantation (TAVI) is an emergent technique for high-risk patients with aortic stenosis. TAVI poses significant challenges about its management because of the procedure itself and the population who undergo the implantation. Two devices are currently available and marketed in Europe and several other technologies are being developed. The retrograde transfemoral approach is the most popular procedure; nevertheless, it may not be feasible in patients with signi?cant aortic or ileo-femoral arterial disease. Alternatives include a transaxillary approach, transapical approach, open surgical access to the retroperitoneal iliac artery and the ascending aorta. A complementary approach using both devices and alternative routes tailored to the anatomy and the comorbidities of the single patient is a main component for the successful implementation of a TAVI program. Anaesthetic strategies vary in different centers. Local anaesthesia or general anaesthesia are both valid alternatives and can be applied according to the patient's characteristics and procedural instances. General anaesthesia offers many advantages, mainly regarding the possibility of an early diagnosis and treatment of possible complications through the use of transesophageal echocardiography. However, after the initial experiences, many groups began to employ, routinely, sedation plus local anaesthesia for TAVI, and their procedural and periprocedural success demonstrates that it is feasible. TAVI is burdened with potential important complications: vascular injuries, arrhythmias, renal impairment, neurological complications, cardiac tamponade, prosthesis malpositioning and embolization and left main coronary artery occlusion. The aim of this work is to review the anaesthetic management of TAVI based on the available literature. PMID:22234024

  12. Characterizations of additive manufactured porous titanium implants.

    PubMed

    Basalah, Ahmad; Shanjani, Yaser; Esmaeili, Shahrzad; Toyserkani, Ehsan

    2012-10-01

    This article describes physical, chemical, and mechanical characterizations of porous titanium implants made by an additive manufacturing method to gain insight into the correlation of process parameters and final physical properties of implants used in orthopedics. For the manufacturing chain, the powder metallurgy technology was combined with the additive manufacturing to fabricate the porous structure from the pure tanium powder. A 3D printing machine was employed in this study to produce porous bar samples. A number of physical parameters such as titanium powder size, polyvinyl alcohol (PVA) amount, sintering temperature and time were investigated to control the mechanical properties and porosity of the structures. The produced samples were characterized through porosity and shrinkage measurements, mechanical compression test and scanning electron microscopy (SEM). The results showed a level of porosity in the samples in the range of 31-43%, which is within the range of the porosity of the cancelluous bone and approaches the range of the porosity of the cortical bone. The results of the mechanical test showed that the compressive strength is in the wide range of 56-509 MPa implying the effect of the process parameters on the mechanical strengths. This technique of manufacturing of Ti porous structures demonstrated a low level of shrinkage with the shrinkage percentage ranging from 1.5 to 5%. PMID:22865677

  13. Modern metal-on-metal hip implants.

    PubMed

    Bozic, Kevin J; Browne, James; Dangles, Chris J; Manner, Paul A; Yates, Adolph J; Weber, Kristy L; Boyer, Kevin M; Zemaitis, Paul; Woznica, Anne; Turkelson, Charles M; Wies, Janet L

    2012-06-01

    This Technology Overview was prepared using systematic review methodology and summarizes the findings of studies published as of July 15, 2011, on modern metal-on-metal hip implants. Analyses conducted on outcomes by two joint registries indicate that patients who receive metal-on-metal total hip arthroplasty (THA) and hip resurfacing are at greater risk for revision than are patients who receive THA using a different bearing surface combination. Data from these registries also indicate that larger femoral head components have higher revision rates and risk of revision and that older age is associated with increased revision risks of large-head metal-on-metal THA. Several studies noted a correlation between suboptimal hip implant positioning and higher wear rates, local metal debris release, and consequent local tissue reactions to metal debris. In addition, several studies reported elevated serum metal ion concentrations in patients with metal-on-metal hip articulations, although the clinical significance of these elevated ion concentrations remains unknown. PMID:22661570

  14. Biostability of an implantable glucose sensor chip

    NASA Astrophysics Data System (ADS)

    Fröhlich, M.; Birkholz, M.; Ehwald, K. E.; Kulse, P.; Fursenko, O.; Katzer, J.

    2012-12-01

    Surface materials of an implantable microelectronic chip intended for medical applications were evaluated with respect to their long-term stability in bio-environments. The sensor chip shall apply in a glucose monitor by operating as a microviscosimeter according to the principle of affinity viscosimetry. A monolithic integration of a microelectromechanical system (MEMS) into the sensor chip was successfully performed in a combined 0.25 ?m CMOS/BiCMOS technology. In order to study material durability and biostability of the surfaces, sensor chips were exposed to various in vitro and in vivo tests. Corrosional damage of SiON, SiO2 and TiN surfaces was investigated by optical microscopy, ellipsometry and AFM. The results served for optimizing the Back-end-of-Line (BEoL) stack, from which the MEMS was prepared. Corrosion of metal lines could significantly be reduced by improving the topmost passivation layer. The experiments revealed no visible damage of the actuator or other functionally important MEMS elements. Sensor chips were also exposed to human body fluid for three month by implantation into the abdomen of a volunteer. Only small effects were observed for layer thickness and Ra roughness after explantation. In particular, TiN as used for the actuator beam showed no degradation by biocorrosion. The highest degradation rate of about 50 nm per month was revealed for the SiON passivation layer. These results suggest that the sensor chip may safely operate in subcutaneous tissue for a period of several months.

  15. Implantable biomedical devices on bioresorbable substrates

    DOEpatents

    Rogers, John A; Kim, Dae-Hyeong; Omenetto, Fiorenzo; Kaplan, David L; Litt, Brian; Viventi, Jonathan; Huang, Yonggang; Amsden, Jason

    2014-03-04

    Provided herein are implantable biomedical devices, methods of administering implantable biomedical devices, methods of making implantable biomedical devices, and methods of using implantable biomedical devices to actuate a target tissue or sense a parameter associated with the target tissue in a biological environment. Each implantable biomedical device comprises a bioresorbable substrate, an electronic device having a plurality of inorganic semiconductor components supported by the bioresorbable substrate, and a barrier layer encapsulating at least a portion of the inorganic semiconductor components. Upon contact with a biological environment the bioresorbable substrate is at least partially resorbed, thereby establishing conformal contact between the implantable biomedical device and the target tissue in the biological environment.

  16. A Paradigm for the Development and Evaluation of Novel Implant Topologies for Bone Fixation: In Vivo Evaluation

    PubMed Central

    Long, Jason P.; Hollister, Scott J.; Goldstein, Steven A.

    2012-01-01

    While contemporary prosthetic devices restore some function to individuals who have lost a limb, there are efforts to develop bio-integrated prostheses to improve functionality. A critical step in advancing this technology will be to securely attach the device to remnant bone. To investigate mechanisms for establishing robust implant fixation in bone while undergoing loading, we previously used a topology optimization scheme to develop optimized orthopaedic implants and then fabricated selected designs from titanium (Ti)-alloy with selective laser sintering (SLS) technology. In the present study, we examined how implant architecture and mechanical stimulation influence osseointegration within an in vivo environment. To do this, we evaluated three implant designs (two optimized and one non-optimized) using a unique in vivo model that applied cyclic, tension/ compression loads to the implants. Eighteen (six per implant design) adult male canines had implants surgically placed in their proximal, tibial metaphyses. Experimental duration was 12 weeks; daily loading (peak load of ±22N for 1000 cycles) was applied to one of each animal’s bilateral implants for the latter six weeks. Following harvest, osseointegration was assessed by non-destructive mechanical testing, micro-computed tomography (microCT) and back-scatter scanning electron microscopy (SEM). Data revealed that implant loading enhanced osseointegration by significantly increasing construct stiffness, peri-implant trabecular morphology, and percentages of interface connectivity and bone ingrowth. While this experiment did not demonstrate a clear advantage associated with the optimized implant designs, osseointegration was found to be significantly influenced by aspects of implant architecture. PMID:22951278

  17. E ects of the Driving Force on the Composition of Natural Gas Hydrates

    E-print Network

    Gudmundsson, Jon Steinar

    concept) or dispersed in condensate or crude to form a pumpable hydrate-in-oil slurry (hydrate slurry- ciates to yield natural gas and water. Such hydrate technology has two important characteristics: Ambient

  18. Or Th Pr Au Cr Two-Year Master Program (120 ECTS)

    E-print Network

    Wolper, Pierre

    focus in sustainable car technologies Compulsory courses Module 1 : Vehicle dynamics and safety MECA0492-2 Vehicle dynamics (english language) - Pierre DUYSINX Q1 30 20 - 4 MECA0493-2 Vehicle aerodynamics (english

  19. Clinical Validation of Percutaneous Cochlear Implant Surgery: Initial Report

    PubMed Central

    Labadie, Robert F.; Noble, Jack H.; Dawant, Benoit M.; Balachandran, Ramya; Majdani, Omid; Fitzpatrick, J. Michael

    2015-01-01

    Objective Percutaneous cochlear implant surgery consists of a single drill path from the lateral mastoid cortex to the cochlea via the facial recess. We sought to clinically validate this technique in patients undergoing traditional cochlear implant surgery. Study Design Prospective clinical trial. Methods After institutional regulatory board approved protocols, five ears were studied via the following steps. 1) In the clinic under local anesthesia, bone-implanted anchors were placed surrounding each mastoid. 2) Temporal-bone computed tomography (CT) scans were obtained. 3) On the CT scans, paths were planned from the lateral mastoid cortex, through the facial recess, to the basal turn of the cochlea both “manually” and “automatically” using computer software. 4) Customized microstereotactic frames were rapid-prototyped to serve as drill guides constraining the drill to follow the appropriate path. 5) During cochlear implant surgery, after drilling of the facial recess, drill guides were mounted on the bone-implanted anchors. 6) Accuracy of paths was assessed via intraoperative photodocumentation. Results All surgical paths successfully traversed the facial recess and hit the basal turn of the cochlea. Distance in millimeters (average SD) from the midpoint of the drill to the facial nerve was 1.18 ± 0.68 for the “manual” path and 1.24 ± 0.44 mm for the “automatic” path and for the chorda tympani 0.986 ± 0.48 for the “manual” path and 1.22 ± 0.62 for the “automatic” path. Conclusions Percutaneous cochlear implant access using customized drill guides based on preoperative CT scans and image-guided surgery technology can be safely accomplished. PMID:18401279

  20. Critical appraisal of cardiac implantable electronic devices: complications and management

    PubMed Central

    Padeletti, Luigi; Mascioli, Giosuè; Perini, Alessandro Paoletti; Grifoni, Gino; Perrotta, Laura; Marchese, Procolo; Bontempi, Luca; Curnis, Antonio

    2011-01-01

    Population aging and broader indications for the implant of cardiac implantable electronic devices (CIEDs) are the main reasons for the continuous increase in the use of pacemakers (PMs), implantable cardioverter-defibrillators (ICDs) and devices for cardiac resynchronization therapy (CRT-P, CRT-D). The growing burden of comorbidities in CIED patients, the greater complexity of the devices, and the increased duration of procedures have led to an augmented risk of infections, which is out of proportion to the increase in implantation rate. CIED infections are an ominous condition, which often implies the necessity of hospitalization and carries an augmented risk of in-hospital death. Their clinical presentation may be either at pocket or at endocardial level, but they can also manifest themselves with lone bacteremia. The management of these infections requires the complete removal of the device and subsequent, specific, antibiotic therapy. CIED failures are monitored by competent public authorities, that require physicians to alert them to any failures, and that suggest the opportune strategies for their management. Although the replacement of all potentially affected devices is often suggested, common practice indicates the replacement of only a minority of devices, as close follow-up of the patients involved may be a safer strategy. Implantation of a PM or an ICD may cause problems in the patients’ psychosocial adaptation and quality of life, and may contribute to the development of affective disorders. Clinicians are usually unaware of the psychosocial impact of implanted PMs and ICDs. The main difference between PM and ICD patients is the latter’s dramatic experience of receiving a shock. Technological improvements and new clinical evidences may help reduce the total burden of shocks. A specific supporting team, providing psychosocial help, may contribute to improving patient quality of life. PMID:22915942

  1. Cochlear implantation updates: the Dallas Cochlear Implant Program.

    PubMed

    Tobey, Emily A; Britt, Lana; Geers, Ann; Loizou, Philip; Loy, Betty; Roland, Peter; Warner-Czyz, Andrea; Wright, Charles G

    2012-06-01

    This report provides an overview of many research projects conducted by the Dallas Cochlear Implant Program, a joint enterprise between the University of Texas at Dallas, the University of Texas Southwestern Medical Center, and Children's Medical Center. The studies extend our knowledge of factors influencing communication outcomes in users of cochlear implants. Multiple designs and statistical techniques are used in the studies described including both cross sectional and longitudinal analyses. Sample sizes vary across the studies, and many of the samples represent large populations of children from North America. Multiple statistical techniques are used by the team to analyze outcomes. The team has provided critical information regarding electrode placement, signal processing, and communication outcomes in users of cochlear implants. PMID:22668764

  2. Cochlear Implantation Updates: The Dallas Cochlear Implant Program

    PubMed Central

    Tobey, Emily A.; Britt, Lana; Geers, Ann; Loizou, Philip; Loy, Betty; Roland, Peter; Warner-Czyz, Andrea; Wright, Charles G.

    2013-01-01

    This report provides an overview of many research projects conducted by the Dallas Cochlear Implant Program, a joint enterprise between The University of Texas at Dallas, The University of Texas Southwestern Medical Center and Children’s Medical Center. The studies extend our knowledge of factors influencing communication outcomes in users of cochlear implants. Multiple designs and statistical techniques are used in the studies described including both cross sectional and longitudinal analyses. Sample sizes vary across the studies and many of the samples represent large populations of children from North America. Multiple statistical techniques are used by the team to analyze outcomes. The team has provided critical information regarding electrode placement, signal processing, and communication outcomes in users of cochlear implants. PMID:22668764

  3. Cochlear and Brainstem Auditory Prostheses “Neural Interface for Hearing Restoration: Cochlear and Brain Stem Implants”

    Microsoft Academic Search

    Jose N. Fayad; Steven R. Otto; Robert V. Shannon; Derald E. Brackmann

    2008-01-01

    This paper discusses the development and implementation of three novel implantable technologies that have advanced the communication abilities of hearing-impaired individuals who cannot benefit from conventional hearing aids. This paper will discuss clinical indications and outcomes and include current technological limitations and future research efforts.

  4. Multicomponent Implant Releasing Dexamethasone

    NASA Astrophysics Data System (ADS)

    Nikkola, L.; Vapalahti, K.; Ashammakhi, N.

    2008-02-01

    Several inflammatory conditions are usually treated with corticosteroids. There are various problems like side effects with traditional applications of steroids, e.g. topical, or systemic routes. Local drug delivery systems have been studied and developed to gain more efficient administration with fewer side effects. Earlier, we reported on developing Dexamethasone (DX) releasing biodegradable fibers. However, their drug release properties were not satisfactory in terms of onset of drug release. Thus, we assessed the development of multicomponent (MC) implant to enhance earlier drug release from such biodegradable fibers. Poly (lactide-co-glycolide) (PLGA) and 2 wt-% and 8 wt-% DX were compounded and extruded with twin-screw extruder to form of fibers. Some of the fibers were sterilized to obtain a change in drug release properties. Four different fiber classes were studied: 2 wt-%, 8 wt-%, sterilized 2 wt-%, and sterilized 8 wt-%. 3×4 different DX-releasing fibers were then heat-pressed to form one multicomponent rod. Half of the rods where sterilized. Drug release was measured from initial fibers and multicomponent rods using a UV/VIS spectrometer. Shear strength and changes in viscosity were also measured. Drug release studies showed that drug release commenced earlier from multicomponent rods than from component fibers. Drug release from multicomponent rods lasted from day 30 to day 70. The release period of sterilized rods extended from day 23 to day 57. When compared to the original component fibers, the drug release from MC rods commenced earlier. The initial shear strength of MC rods was 135 MPa and decreased to 105 MPa during four weeks of immersion in phosphate buffer solution. Accordingly, heat pressing has a positive effect on drug release. After four weeks in hydrolysis, no disintegration was observed.

  5. Cochlear Implantation in Older Adults

    PubMed Central

    Lin, Frank R.; Chien, Wade W.; Li, Lingsheng; Niparko, John K.; Francis, Howard W.

    2012-01-01

    Cochlear implants allow individuals with severe-to-profound hearing loss access to sound and spoken language. The number of older adults in the United States who are potential candidates for cochlear implantation is approximately 150,000 and will continue to increase with the aging of the population. Should cochlear implantation (CI) be routinely recommended for these older adults, and do these individuals benefit from CI? We reviewed our 12 year experience with cochlear implantation in adults ?60 years (n = 445) at Johns Hopkins to investigate the impact of CI on speech understanding and to identify factors associated with speech performance. Complete data on speech outcomes at baseline and 1 year post-CI were available for 83 individuals. Our results demonstrate that cochlear implantation in adults ?60 years consistently improved speech understanding scores with a mean increase of 60. 0% (S. D. 24. 1) on HINT sentences in quiet . The magnitude of the gain in speech scores was negatively associated with age at implantation such that for every increasing year of age at CI the gain in speech scores was 1. 3 percentage points less (95% CI: 0. 6 – 1. 9) after adjusting for age at hearing loss onset. Conversely, individuals with higher pre-CI speech scores (HINT scores between 40–60%) had significantly greater post-CI speech scores by a mean of 10. 0 percentage points (95% CI: 0. 4 – 19. 6) than those with lower pre-CI speech scores (HINT <40%) after adjusting for age at CI and age at hearing loss onset. These results suggest that older adult CI candidates who are younger at implantation and with higher preoperative speech scores obtain the highest speech understanding scores after cochlear implantation with possible implications for current Medicare policy. Finally, we provide an extended discussion of the epidemiology and impact of hearing loss in older adults. Future research of CI in older adults should expand beyond simple speech outcomes to take into account the broad cognitive, social, and physical functioning outcomes that are likely detrimentally impacted by hearing loss and may be mitigated by cochlear implantation. PMID:22932787

  6. The Nuclear Energy Advanced Modeling and Simulation Enabling Computational Technologies FY09 Report

    SciTech Connect

    Diachin, L F; Garaizar, F X; Henson, V E; Pope, G

    2009-10-12

    In this document we report on the status of the Nuclear Energy Advanced Modeling and Simulation (NEAMS) Enabling Computational Technologies (ECT) effort. In particular, we provide the context for ECT In the broader NEAMS program and describe the three pillars of the ECT effort, namely, (1) tools and libraries, (2) software quality assurance, and (3) computational facility (computers, storage, etc) needs. We report on our FY09 deliverables to determine the needs of the integrated performance and safety codes (IPSCs) in these three areas and lay out the general plan for software quality assurance to meet the requirements of DOE and the DOE Advanced Fuel Cycle Initiative (AFCI). We conclude with a brief description of our interactions with the Idaho National Laboratory computer center to determine what is needed to expand their role as a NEAMS user facility.

  7. A pulse transformer for plasma immersion ion implantation applications

    Microsoft Academic Search

    V. Spassov; J. Barroso; M. Ueda

    2001-01-01

    Plasma Immersion Ion Implantation (PIII) applies a series of negative high-voltage pulses to a sample (target) immersed in plasma. PIII is a technology used to modify the material surface properties of a variety of products, e.g. for the manufacturing of semiconductor junctions and oxides, and for the production of high-strength, light-weight corrosion-resistant aerospace components. The pulse transformers become an essential

  8. Fully integrated PLL based clock generator for implantable biomedical applications

    Microsoft Academic Search

    Garrett Bischof; Ben Scholnick; Emre Salman

    2011-01-01

    The design and verification of an ultra low power phase-locked loop (PLL) with application to implantable biomedical systems is presented. A systematic PLL design methodology is introduced, where the first step is a high level characterization of the system in MATLAB. The second step involves a transistor level implementation in Cadence using 0.35µm CMOS technology. The proposed low power and

  9. The Aula EspaZio Gela and the Master of Space Science and Technology in the Universidad Del País Vasco (University of the Basque Country)

    ERIC Educational Resources Information Center

    Sánchez-Lavega, Agustín; Pérez-Hoyos, Santiago; Hueso, Ricardo; del Río-Gaztelurrutia, Teresa; Oleaga, Alberto

    2014-01-01

    We present the Aula EspaZio Gela, a facility dedicated to teaching Space Science and Technology at the master and doctorate level at the University of the Basque Country (Spain), and to promoting the development of this field in both public and private sectors. The one-year master's degree in Space Science and Technology (60 ECTS (European…

  10. Analysis of the results of four years of research and application of a student-centered system based on the ECTS to first-year students in order to improve their performance in the subject ACI

    Microsoft Academic Search

    Wilmar Hernandez; Javier Palmero; Manuel Labrador; Jorge Bonache; Carmen Cousido; A. A?lvarez-Vellisco; J. M. Gutie?rrez-Arriola; J. Jimenez-Trillo

    2010-01-01

    In this paper, the results of four years of a research aimed at carrying out a comparative analysis between the application of the European Credit Transfer and Accumulation System (ECTS) and the traditional teaching and learning system (TTLS) to first-year students, in order to improve their performance in the subject Analysis of Circuits I (AC-I) are presented. The ECTS is

  11. Rhenium ion beam for implantation into semiconductors

    SciTech Connect

    Kulevoy, T. V.; Seleznev, D. N.; Alyoshin, M. E.; Kraevsky, S. V.; Yakushin, P. E.; Khoroshilov, V. V. [Institute for Theoretical and Experimental Physics, Moscow (Russian Federation); Gerasimenko, N. N.; Smirnov, D. I. [National Research University of Electronic Technology ''MIET'', Moscow (Russian Federation); Fedorov, P. A. [Institute for Theoretical and Experimental Physics, Moscow (Russian Federation); National Research University of Electronic Technology ''MIET'', Moscow (Russian Federation); Temirov, A. A. [National University of Science and Technology ''MISIS'', Moscow (Russian Federation)

    2012-02-15

    At the ion source test bench in Institute for Theoretical and Experimental Physics the program of ion source development for semiconductor industry is in progress. In framework of the program the Metal Vapor Vacuum Arc ion source for germanium and rhenium ion beam generation was developed and investigated. It was shown that at special conditions of ion beam implantation it is possible to fabricate not only homogenous layers of rhenium silicides solid solutions but also clusters of this compound with properties of quantum dots. At the present moment the compound is very interesting for semiconductor industry, especially for nanoelectronics and nanophotonics, but there is no very developed technology for production of nanostructures (for example quantum sized structures) with required parameters. The results of materials synthesis and exploration are presented.

  12. Rhenium ion beam for implantation into semiconductors.

    PubMed

    Kulevoy, T V; Gerasimenko, N N; Seleznev, D N; Fedorov, P A; Temirov, A A; Alyoshin, M E; Kraevsky, S V; Smirnov, D I; Yakushin, P E; Khoroshilov, V V

    2012-02-01

    At the ion source test bench in Institute for Theoretical and Experimental Physics the program of ion source development for semiconductor industry is in progress. In framework of the program the Metal Vapor Vacuum Arc ion source for germanium and rhenium ion beam generation was developed and investigated. It was shown that at special conditions of ion beam implantation it is possible to fabricate not only homogenous layers of rhenium silicides solid solutions but also clusters of this compound with properties of quantum dots. At the present moment the compound is very interesting for semiconductor industry, especially for nanoelectronics and nanophotonics, but there is no very developed technology for production of nanostructures (for example quantum sized structures) with required parameters. The results of materials synthesis and exploration are presented. PMID:22380345

  13. Morphofunctional aspects of dental implants.

    PubMed

    Meyer, Georg; Fanghänel, Jochen; Proff, Peter

    2012-03-20

    Although oral implantology is among the most beneficial developments of modern dentistry, the widely spread opinion that the long-term outcome of implants is superior to that of natural teeth has been refuted. To evade uncritical extractions, the morphofunctional properties of natural teeth and implant-supported restorations are compared from a proprioceptive and occlusal trauma perspective. The periodontal ligament of natural teeth provides the central nerve system with feedback for sensory perception and motor control. Conversely, the lack of such proprioception causes lower tactile sensitivity and less coordinated masticatory muscle activity in implant-borne restorations and makes them more prone to occlusal overload and possible subsequent failure. Moreover, occlusal anomalies may be conducive to parafunctional activity, craniomandibular disorder, tinnitus, and headache. Oral implantology, therefore, has to take appropriate account of occlusal conditions and the biomechanical and neuromuscular aspects of masticatory function. PMID:22137145

  14. Analysis of induced electrical currents from magnetic field coupling inside implantable neurostimulator leads

    PubMed Central

    2011-01-01

    Background Over the last decade, the number of neurostimulator systems implanted in patients has been rapidly growing. Nearly 50, 000 neurostimulators are implanted worldwide annually. The most common type of implantable neurostimulators is indicated for pain relief. At the same time, commercial use of other electromagnetic technologies is expanding, making electromagnetic interference (EMI) of neurostimulator function an issue of concern. Typically reported sources of neurostimulator EMI include security systems, metal detectors and wireless equipment. When near such sources, patients with implanted neurostimulators have reported adverse events such as shock, pain, and increased stimulation. In recent in vitro studies, radio frequency identification (RFID) technology has been shown to inhibit the stimulation pulse of an implantable neurostimulator system during low frequency exposure at close distances. This could potentially be due to induced electrical currents inside the implantable neurostimulator leads that are caused by magnetic field coupling from the low frequency identification system. Methods To systematically address the concerns posed by EMI, we developed a test platform to assess the interference from coupled magnetic fields on implantable neurostimulator systems. To measure interference, we recorded the output of one implantable neurostimulator, programmed for best therapy threshold settings, when in close proximity to an operating low frequency RFID emitter. The output contained electrical potentials from the neurostimulator system and those induced by EMI from the RFID emitter. We also recorded the output of the same neurostimulator system programmed for best therapy threshold settings without RFID interference. Using the Spatially Extended Nonlinear Node (SENN) model, we compared threshold factors of spinal cord fiber excitation for both recorded outputs. Results The electric current induced by low frequency RFID emitter was not significant to have a noticeable effect on electrical stimulation. Conclusions We demonstrated a method for analyzing effects of coupled magnetic field interference on implantable neurostimulator system and its electrodes which could be used by device manufacturers during the design and testing phases of the development process. PMID:22014169

  15. A low-power cochlear implant system

    E-print Network

    Baker, Michael W. (Michael Warren), 1977-

    2007-01-01

    Cochlear implants, or bionic ears, restore hearing to the profoundly deaf by bypassing missing inner-ear hair cells in the cochlea and electrically stimulating the auditory nerve. For miniaturized cochlear implants, including ...

  16. Educational Challenges for Children with Cochlear Implants.

    ERIC Educational Resources Information Center

    Chute, Patricia M.; Nevins, Mary Ellen

    2003-01-01

    This article addresses educational challenges for children with severe to profound hearing loss who receive cochlear implants. Despite the implants, these children face acoustic challenges, academic challenges, attention challenges, associative challenges, and adjustment challenges. (Contains references.) (Author/DB)

  17. Benefits and Risks of Cochlear Implants

    MedlinePLUS

    ... systems Will have to be careful of static electricity. Static electricity may temporarily or permanently damage a cochlear implant. ... more details regarding how to deal with static electricity, contact the manufacturer or implant center. Have less ...

  18. 21 CFR 522.1350 - Melatonin implant.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...One implant per mink. (2) Indications for use. For use in healthy male and female kit and adult female mink (Mustela vison ) to accelerate the fur priming cycle. (3) Limitations. For subcutaneous implantation in mink only....

  19. 21 CFR 522.1350 - Melatonin implant.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...One implant per mink. (2) Indications for use . For use in healthy male and female kit and adult female mink (Mustela vison ) to accelerate the fur priming cycle. (3) Limitations . For subcutaneous implantation in mink only....

  20. 21 CFR 522.1350 - Melatonin implant.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...One implant per mink. (2) Indications for use . For use in healthy male and female kit and adult female mink (Mustela vison ) to accelerate the fur priming cycle. (3) Limitations . For subcutaneous implantation in mink only....

  1. Implanting Beef Calves and Stocker Cattle 

    E-print Network

    McCollum III, Ted

    1998-04-24

    Implanting beef calves offers one of the highest benefit-to-cost ratios of all the management practices available to cow/calf and stocker cattle producers. This publication offers advice on implant administration....

  2. Neurophysiologic Basis for Cochlear and Auditory Brainstem Implants

    E-print Network

    O'Toole, Alice J.

    Neurophysiologic Basis for Cochlear and Auditory Brainstem Implants Aage R. Møller Callier Center for cochlear and brainstem implants is discussed. It is concluded that the success of cochlear implants may: cochlear implants, brainstem implants, auditory physiology. Cochlear implants were pioneered by Michelson

  3. Investigations of silicone breast implants with the NMR-MOUSE

    Microsoft Academic Search

    Mirko Krüger; Annett Schwarz; Bernhard Blümich

    2007-01-01

    Silicone breast implants are used for breast augmentation and breast reconstruction. The issues of concern associated with such implants are: (a) the quality control of each implant before implantation, and (b) the detection of implant bleeding after implantation. We have studied the use of the Nuclear Magnetic Resonance–MObile Universal Surface Explorer (NMR-MOUSE) for the nondestructive testing of (a) the quality

  4. Secondary ion mass spectrometry characterization of indium-implanted silicon wafers

    NASA Astrophysics Data System (ADS)

    Blackmer-Krasinski, C.; Morinville, W. R.

    2004-06-01

    Indium is a key element in the formation of well, channel, and halo profiles in semiconductor fabrication. Indium has the advantage of being a large atom with a small projected range, creating a steeper implant profile than the boron implant used in the past [Proceedings of the 14th International Conference on Ion Implantation Technology, ITT, 2002]. Typically, secondary ion mass spectrometry (SIMS) is used to provide implant profiles; however, when a set of indium-implanted samples were analyzed on the Cameca IMS-6F, non-repeatability of the implant profile was observed in the samples that had not received an oxide spacer prior to implantation. This non-repeatability was not observed when the same samples were analyzed on the Perkin-Elmer 6300 quadrupole secondary ion mass spectrometer. Several reasons for this were hypothesized: (1) an amorphous layer was being created due to the large size of the indium atom; (2) increased damage and surface roughening occurred on the samples that did not receive an oxide layer prior to implantation; (3) Gibbsian segregation similar to that of Cu in SiO 2 was being observed [Secondary Ion Mass Spectrometry, Wiley, New York, 1989, p. 2.2-1]; and (4) sample heating was changing the thermodynamic properties of the samples. To explore these possibilities, two sets of indium-implanted samples—with and without spacer oxide—were analyzed with atomic force microscopy (AFM) for surface roughness and with transmission electron microscopy (TEM) for differences in amorphization. SIMS analysis was also conducted on both types of dynamic SIMS instruments to develop an analytical protocol for determining the indium implant profile. Repeatable results, consistent with analysis on the quadrupole SIMS, were obtained by utilizing the cold finger on the Cameca 6F.

  5. Body Contouring with Solid Silicone Implants

    Microsoft Academic Search

    Gerardo Flores-Lima; Barry L. Eppley

    2009-01-01

    Background  Body-contouring implants are becoming increasingly popular and more accepted and requested for aesthetic purposes. These implants\\u000a must be placed in a safe and reproducible plane of anatomic dissection for a successful long-term outcome. Poor implant placement\\u000a techniques result in greater complications such as asymmetry, implant migration, capsular contracture, and infection. This\\u000a article discusses (1) the history and the evolution of

  6. Radiographic evaluation of hip implants.

    PubMed

    Chang, Connie Y; Huang, Ambrose J; Palmer, William E

    2015-02-01

    Serial radiographs are the mainstay in the longitudinal assessment of hip implants. The prosthesis, periprosthetic bone, and juxta-articular soft tissues are inspected for fracture, periosteal reaction, stress shielding, calcar resorption, osteolysis, bony remodeling, metallic debris, and heterotopic ossification. Comparison radiographs best confirm implant migration, subsidence, and aseptic loosening. Infection, particle disease, reaction to metal, and mechanical impingement are important causes of postsurgical pain, but in their earliest stages they may be difficult to diagnose using radiographs. This article addresses the role of radiography following hip arthroplasty. PMID:25633021

  7. Mutation breeding by ion implantation

    NASA Astrophysics Data System (ADS)

    Yu, Zengliang; Deng, Jianguo; He, Jianjun; Huo, Yuping; Wu, Yuejin; Wang, Xuedong; Lui, Guifu

    1991-07-01

    Ion implantation as a new mutagenic method has been used in the rice breeding program since 1986, and for mutation breeding of other crops later. It has been shown, in principle and in practice, that this method has many outstanding advantages: lower damage rate; higher mutation rate and wider mutational spectrum. Many new lines of rice with higher yield rate; broader disease resistance; shorter growing period but higher quality have been bred from ion beam induced mutants. Some of these lines have been utilized for the intersubspecies hybridization. Several new lines of cotton, wheat and other crops are now in breeding. Some biophysical effects of ion implantation for crop seeds have been studied.

  8. Cyborg Technology

    NSDL National Science Digital Library

    Discussions of cyborg technology tend to be relegated to science fiction literature and TV programs like Star Trek. This Topic in Depth looks into current issues and developments in the area of cyborg technology. The first website, from the UC Santa Barbara Department of English, (1) lists a variety of resources on cyborgs, from philosophical articles and literary criticism to current scientific practices. A related area of research is brain-computer interfacing (BCI), which is described on this website from the Helsinki Institute of Technology (2). Research on neural engineering, which combines work in electrical and computer engineering, tissue engineering, materials science, and nanotechnology, is also described on this website from USC (3). The Discovery School (4) suggests this lesson on technology for grades six through eight, in which students explore how the human body uses electric signals to send messages to and from the brain, and then how the nervous system uses those signals, with the option for additional discussions regarding the potential for cyborg technology. The next website from National Public Radio (5) provides a current look at applications of cyber technology, most of which are in the area of healthcare. For example, this program reports on how "scientists make it possible for quadriplegics to control a television, play simple computer games and check e-mail... by just thinking about it." Another interesting experiment--Project Cyborg--involves the neuro-surgical implantation of a device into the median nerves of this researchers' left arm and is described this website (6).

  9. Implants and Ethnocide: Learning from the Cochlear Implant Controversy

    ERIC Educational Resources Information Center

    Sparrow, Robert

    2010-01-01

    This paper uses the fictional case of the "Babel fish" to explore and illustrate the issues involved in the controversy about the use of cochlear implants in prelinguistically deaf children. Analysis of this controversy suggests that the development of genetic tests for deafness poses a serious threat to the continued flourishing of Deaf culture.…

  10. Redistribution of implanted dopants in GaN

    SciTech Connect

    Cao, X.A. [Univ. of Florida, Gainesville, FL (United States). Dept. of Materials Science and Engineering; Wilson, R.G. [Wilson (R.G.), Stevenson Ranch, CA (United States); Zolper, J.C. [Office of Naval Research, Arlington, VA (United States)] [and others

    1999-03-01

    Ion implantation is an effective technology for selected-area doping or isolation of GaN-based devices. As reviewed previously by Zolper, implantation of donors at high dose (> 5 {times} 10{sup 14} cm{sup {minus}2}) can be used to decrease source and drain access resistance in field effect transistors (FETs), at lower doses to create channel regions for FETs, while sequential implantation of both acceptors and donors may be used to fabricate p-n junctions. Donor (S, Se, and Te) and acceptor (Mg, Be, and C) dopants have been implanted into GaN at doses of 3--5 {times} 10{sup 14} cm{sup {minus}2} and annealed at temperatures up to 1,450 C. No redistribution of any of the elements is detectable by secondary ion mass spectrometry, except for Be, which displays behavior consistent with damage-assisted diffusion at 900 C. At higher temperatures, there is no further movement of the Be, for peak annealing temperature durations of 10 s. Effective diffusivities are {le} 2 {times} 10{sup {minus}13} cm{sup 2} {center_dot} s{sup {minus}1} at 1,450 C for each of the dopants in GaN.

  11. Osseointegrated dental implants produced via microwave processing

    Microsoft Academic Search

    Muralithran G. Kutty

    2004-01-01

    This research is a comprehensive effort to develop osseointegrated dental implants via microwave processing. A net-shape microwave sintering procedure was employed to fabricate dental implants. Commercial pure titanium powders (-100, -200 and -325 mesh sizes) were used in this work. This process eliminates the need for machining of implants and prevents contamination. The idea was to take advantage of the

  12. Bisphosphonates and dental implants: Current problems

    Microsoft Academic Search

    Antonio-Juan Flichy-Fernández; José Balaguer-Martínez; Miguel Peñarrocha-Diago; José V. Bagán

    Osteonecrosis of the jaw has been described in patients taking bisphosphonates after oral surgery procedures, including the placement of dental implants. This review is an update of the relationship between bisphosphonates and dental implants. Results obtained by different authors are compared, contrasting earlier studies where an improvement in implant osseointegration using bisphosphonates was observed, with ones where statistically significant differences

  13. Gender Categorization in Cochlear Implant Users

    E-print Network

    JSLHR Article Gender Categorization in Cochlear Implant Users Zoé Massida,a,b Mathieu Marx: In this study, the authors examined the ability of subjects with cochlear implants (CIs) to discriminate voice the dissociation between recovery of speech recognition and voice feature perception after cochlear implantation

  14. Silicon radiation measurements around mammary type implants

    Microsoft Academic Search

    P. Wilflingseder; G. Hoinkes; H. Hussl; Ch. Papp; G. Mikuz; A. Propst

    1982-01-01

    The Silicon Elastomers, which are widely being used in Plastic and Reconstructive Surgery cause a constrictive fibrosis to a varying degree. The intensity determinations of Silicon radiation show that all capsules around those implants contain intra- and extracellular particles, deriving from the implants. In order to measure the suitability of implant materials manufactured from Silicon Elastomers as well as to

  15. Security and Privacy for Implantable Medical Devices

    Microsoft Academic Search

    Daniel Halperin; Thomas S. Heydt-benjamin; Kevin Fu; Tadayoshi Kohno; William H. Maisel

    2008-01-01

    Protecting implantable medical devices against attack without compromising patient health requires balancing security and privacy goals with traditional goals such as safety and utility. Implantable medical devices monitor and treat physiological conditions within the body. These devices - including pacemakers, implantable cardiac defibrillators (ICDs), drug delivery systems, and neurostimulators - can help manage a broad range of ailments, such as

  16. Foreign body reaction after cochlear implantation

    Microsoft Academic Search

    Hye Jin Lim; Eun-So Lee; Hun Yi Park; Yun-Hoon Choung

    2011-01-01

    Cochlear implantation is a widely accepted, safe procedure for patients with severe to profound sensorineuronal hearing loss. While complications are rare, revision surgeries are required for complications like device failure, misplaced electrode, flap necrosis, and wound infection. Foreign body reaction is a rare complication following cochlear implantation. We experienced a case of foreign body reaction after cochlear implantation treated by

  17. Myths about Cochlear Implants: A Family Perspective.

    ERIC Educational Resources Information Center

    Luetke-Stahlman, B.

    1994-01-01

    A parent of two young children who received cochlear implant surgery addresses common myths about this procedure including "deaf people don't support the use of cochlear implants,""if you choose cochlear implant surgery, you are choosing the hearing world,""hearing parents are not qualified to decide," and "the deaf child him/herself should…

  18. MICHIGAN TECHNOLOGICAL UNIVERSITY / 2014 of engineering

    E-print Network

    sensors beam good news --and bad-- from deep inside an artificial knee. Hip implants etched with nanotubes to an artificial limb. #12;TABLEOFCONTENTS They come in peace Drone technology developed for defense is making life

  19. Urbanization EffEcts on spottEd salamandEr and Wood frog prEsEncE and abUndancE

    E-print Network

    Reed, Michael

    Urbanization EffEcts on spottEd salamandEr and Wood frog prEsEncE and abUndancE Peter J. Clark1 , J residential, and green space, as well as road length. Abundance was evaluated only for occupied ponds. Most. maculatum abundance model explained only 18% of the variability. Canopy cover over ponds was important in A

  20. E! ect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial

    Microsoft Academic Search

    Jane Durga; Martin P J van Boxtel; Evert G Schouten; Frans J Kok; Jelle Jolles; Martijn B Katan; Petra Verhoef

    2007-01-01

    Background Low folate and raised homocysteine concentrations in blood are associated with poor cognitive performance in the general population. As part of the FACIT trial to assess the e! ect of folic acid on markers of atherosclerosis in men and women aged 50-70 years with raised plasma total homocysteine and normal serum vitamin B12 at screening, we report here the

  1. E ect of the reservoir size on gas adsorption in inhomogeneous porous media E. Kierlik, 1 J. Puibasset, 2 and G. Tarjus 1

    E-print Network

    Recanati, Catherine

    E#11;ect of the reservoir size on gas adsorption in inhomogeneous porous media E. Kierlik, 1 J characterized by many local minima, i.e. metastable states.[2{4] The above picture of gas adsorption of the reservoir on the adsorption isotherms of a uid in disordered or inhomogeneous mesoporous solids. We

  2. Single-cycle degree Where CFU/ECTS Hours Course Language Professor Law and Jurisprudence Padova 6 48 Advanced international law English Andrea Gattini

    E-print Network

    Schenato, Luca

    and Jurisprudence Padova 6 48 Zivilrecht German to be assigned Courses in English or other foreign languagesSingle-cycle degree Where CFU/ECTS Hours Course Language Professor Law and Jurisprudence Padova 6 48 Advanced international law English Andrea Gattini Law and Jurisprudence Padova 6 48 Banking Law

  3. UE-IADE-ADE3 : SYSTEME D'INFORMATION POUR LA SUPPLY CHAIN ECTS Cours (h) T.D. (h) T.P. (h) Stage (semaines) Soutien (h)

    E-print Network

    Chaine, Raphaëlle

    9/14 UE-IADE-ADE3 : SYSTEME D'INFORMATION POUR LA SUPPLY CHAIN ECTS Cours (h) T.D. (h) T.P. (h systèmes d'information pour la gestion et le pilotage des chaînes logistiques (Supply Chain). Les pratique. Enfin, les pratiques collaboratives s'appuyant sur l'information sont présentées ; l'impact des

  4. Radiative corrections to the lattice gluon action for highly improved staggered quarks (HISQ) and the e#ect of such corrections on the static potential

    E-print Network

    hep­lat 0812.0503 ########### Radiative corrections to the lattice gluon action for highly improved staggered quarks (HISQ) and the e#ect of such corrections on the static potential A. Hart, 1 G.M von Hippel of dynamical HISQ fermions on the per­ turbative improvement of the gluonic action in the same way as we have

  5. ROBOTICS SCIENCE AND SYSTEMS 2010: WORKSHOP ON ENABLING TECHNOLOGIES 1 Toward Automation of Image-Guided

    E-print Network

    Webster III, Robert James

    -Guided Microstereotactic Frames: A Bone-Attached Parallel Robot for Percutaneous Cochlear Implantation Louis B. Kratchman into the surgical and technological workflow of PCI. Index Terms--Cochlear implant, parallel robot, Gough- Stewart in applications requiring sub-millimetric accuracy, including cochlear implant surgery. In these cases, rigid, non

  6. Synthesis of 5-Hydroxyectoine from Ectoine: Crystal Structure of the Non-Heme Iron(II) and 2-Oxoglutarate-Dependent Dioxygenase EctD

    PubMed Central

    Reuter, Klaus; Pittelkow, Marco; Bursy, Jan; Heine, Andreas; Craan, Tobias; Bremer, Erhard

    2010-01-01

    As a response to high osmolality, many microorganisms synthesize various types of compatible solutes. These organic osmolytes aid in offsetting the detrimental effects of low water activity on cell physiology. One of these compatible solutes is ectoine. A sub-group of the ectoine producer's enzymatically convert this tetrahydropyrimidine into a hydroxylated derivative, 5-hydroxyectoine. This compound also functions as an effective osmostress protectant and compatible solute but it possesses properties that differ in several aspects from those of ectoine. The enzyme responsible for ectoine hydroxylation (EctD) is a member of the non-heme iron(II)-containing and 2-oxoglutarate-dependent dioxygenases (EC 1.14.11). These enzymes couple the decarboxylation of 2-oxoglutarate with the formation of a high-energy ferryl-oxo intermediate to catalyze the oxidation of the bound organic substrate. We report here the crystal structure of the ectoine hydroxylase EctD from the moderate halophile Virgibacillus salexigens in complex with Fe3+ at a resolution of 1.85 Å. Like other non-heme iron(II) and 2-oxoglutarate dependent dioxygenases, the core of the EctD structure consists of a double-stranded ?-helix forming the main portion of the active-site of the enzyme. The positioning of the iron ligand in the active-site of EctD is mediated by an evolutionarily conserved 2-His-1-carboxylate iron-binding motif. The side chains of the three residues forming this iron-binding site protrude into a deep cavity in the EctD structure that also harbours the 2-oxoglutarate co-substrate-binding site. Database searches revealed a widespread occurrence of EctD-type proteins in members of the Bacteria but only in a single representative of the Archaea, the marine crenarchaeon Nitrosopumilus maritimus. The EctD crystal structure reported here can serve as a template to guide further biochemical and structural studies of this biotechnologically interesting enzyme family. PMID:20498719

  7. Biofunctionalization of surfaces by energetic ion implantation: Review of progress on applications in implantable biomedical devices and antibody microarrays

    NASA Astrophysics Data System (ADS)

    Bilek, Marcela M. M.

    2014-08-01

    Despite major research efforts in the field of biomaterials, rejection, severe immune responses, scar tissue and poor integration continue to seriously limit the performance of today's implantable biomedical devices. Implantable biomaterials that interact with their host via an interfacial layer of active biomolecules to direct a desired cellular response to the implant would represent a major and much sought after improvement. Another, perhaps equally revolutionary, development that is on the biomedical horizon is the introduction of cost-effective microarrays for fast, highly multiplexed screening for biomarkers on cell membranes and in a variety of analyte solutions. Both of these advances will rely on effective methods of functionalizing surfaces with bioactive molecules. After a brief introduction to other methods currently available, this review will describe recently developed approaches that use energetic ions extracted from plasma to facilitate simple, one-step covalent surface immobilization of bioactive molecules. A kinetic theory model of the immobilization process by reactions with long-lived, mobile, surface-embedded radicals will be presented. The roles of surface chemistry and microstructure of the ion treated layer will be discussed. Early progress on applications of this technology to create diagnostic microarrays and to engineer bioactive surfaces for implantable biomedical devices will be reviewed.

  8. New advanced surface modification technique: titanium oxide ceramic surface implants: long-term clinical results

    NASA Astrophysics Data System (ADS)

    Szabo, Gyorgy; Kovacs, Lajos; Barabas, Jozsef; Nemeth, Zsolt; Maironna, Carlo

    2001-11-01

    The purpose of this paper is to discuss the background to advanced surface modification technologies and to present a new technique, involving the formation of a titanium oxide ceramic coating, with relatively long-term results of its clinical utilization. Three general techniques are used to modify surfaces: the addition or removal of material and the change of material already present. Surface properties can also be changed without the addition or removal of material, through the laser or electron beam thermal treatment. The new technique outlined in this paper relates to the production of a corrosion-resistant 2000-2500 A thick, ceramic oxide layer with a coherent crystalline structure on the surface of titanium implants. The layer is grown electrochemically from the bulk of the metal and is modified by heat treatment. Such oxide ceramic-coated implants have a number of advantageous properties relative to implants covered with various other coatings: a higher external hardness, a greater force of adherence between the titanium and the oxide ceramic coating, a virtually perfect insulation between the organism and the metal (no possibility of metal allergy), etc. The coated implants were subjected to various physical, chemical, electronmicroscopic, etc. tests for a qualitative characterization. Finally, these implants (plates, screws for maxillofacial osteosynthesis and dental root implants) were applied in surgical practice for a period of 10 years. Tests and the experience acquired demonstrated the good properties of the titanium oxide ceramic-coated implants.

  9. Modification of anti-bacterial surface properties of textile polymers by vacuum arc ion source implantation

    NASA Astrophysics Data System (ADS)

    Nikolaev, A. G.; Yushkov, G. Yu.; Oks, E. M.; Oztarhan, A.; Akpek, A.; Hames-Kocabas, E.; Urkac, E. S.; Brown, I. G.

    2014-08-01

    Ion implantation provides an important technology for the modification of material surface properties. The vacuum arc ion source is a unique instrument for the generation of intense beams of metal ions as well as gaseous ions, including mixed metal-gas beams with controllable metal:gas ion ratio. Here we describe our exploratory work on the application of vacuum arc ion source-generated ion beams for ion implantation into polymer textile materials for modification of their biological cell compatibility surface properties. We have investigated two specific aspects of cell compatibility: (i) enhancement of the antibacterial characteristics (we chose to use Staphylococcus aureus bacteria) of ion implanted polymer textile fabric, and (ii) the "inverse" concern of enhancement of neural cell growth rate (we chose Rat B-35 neuroblastoma cells) on ion implanted polymer textile. The results of both investigations were positive, with implantation-generated antibacterial efficiency factor up to about 90%, fully comparable to alternative conventional (non-implantation) approaches and with some potentially important advantages over the conventional approach; and with enhancement of neural cell growth rate of up to a factor of 3.5 when grown on suitably implanted polymer textile material.

  10. Cerec meets Galileos--integrated implantology for completely virtual implant planning.

    PubMed

    Reiz, Stefan D; Neugebauer, Jörg; Karapetian, Viktor-E; Ritter, Lutz

    2014-01-01

    The greatest key to successful implant therapy is proper placement of the implant in the jaw bone. The key to proper placement is careful preoperative planning. When planning implant treatment, it is important to take the relevant anatomical features and their later prosthetic consequences into account. This is done using a radiographic template of the planned restoration, which until now had to be made by a dental technician. The radiographic template must be inserted in the patient's mouth during radiographic imaging so that the dentist can visualize the prosthetic plan. Implant planning is thus performed according to the backward planning principle. In the novel, fully digital approach to dental implant planning presented here, the prosthetic proposal is designed using computer-aided design software and integrated into a three-dimensional radiograph. This article explains how the technology works and reviews the available data. In addition, the clinical workflows for the SiCAT Optiguide and Sirona Cerec Guide virtual implant planning methods will be described and compared with conventional implant planning methods. Finally, the indications and countraindications for the two methods will be discussed. PMID:25098162

  11. Nissin Ion Doping System--H{sub 2}{sup +} Implantation for Silicon Layer Exfoliation

    SciTech Connect

    Cherekdjian, S.; Maschmeyer, R. O. [PrO Unlimited (on assignment at Corning Incorporated) Corning NY 14831 (United States); Cites, J. [Corning Incorporated, Corning NY 14831 (United States); Tatemichi, J.; Inouchi, Y.; Onoda, M.; Orihira, K.; Matsumoto, T.; Konishi, M.; Naito, M. [Nissin Ion Equipment Co., Ltd., 29, Hinokigaoka, Minakuchi-cho, Koka, Shiga, 528-0068888 (Japan)

    2011-01-07

    A Nissin iG4 ion doping system (termed iG4) utilizes broad beam technology to implant GEN 4 sheets of glass for LCD production. The mechanical scanned end-station with robotic handling for GEN 4 glass substrates was redesigned, and a new end-station was built to handle rectangular silicon tiles (23x18 cm). A three sub-system modular risk reduction process was used to test production solutions, and maximize the success of transferring the R and D implant recipes developed on a standard focused beam ion implanter to the Nissin broad beam iG4 solution. The silicon tile end-station including the implant scanning system was tested for reliability and durability. The end-station handled rectangular silicon tiles reliably without detrimental edge chipping or silicon breakage. The ion optics was demonstrated to successfully provide stable hydrogen ions for the Corning registered silicon on glass layer transfer process. This layer transfer process is very susceptible and sensitive to the implant processing temperature. The temperature excursions during implant processing for the iG4 exfoliation process were found to be in line with the R and D focused ion beam system. This data confirmed the system production-readiness in providing an efficient solution for the high volume production of hydrogen implanted silicon rectangular tiles.

  12. Bioceramic Coatings for Orthopaedic Implants

    SciTech Connect

    Campbell, Allison A.

    2003-11-02

    During the past century, man-made materials and devices have been developed to the point at which they have been used successfully to replace and/or restore function to diseased or damaged tissues. In the field of orthopaedics, the use of metal implants has significantly improved the quality of life for countless individuals. Critical factors for implant success include proper design, material selection, and biocompatibility. While early research focused on the understanding biomechanical properties of the metal device, recent work has turned toward improving the biological properties of these devices. This has lead to the introduction of calcium phosphate (CaP) bioceramics as a bioactive interface between the bulk metal impart and the surrounding tissue. The first calcium phosphate coatings where produced via vapor phase routes but more recently, there has been the emergence of solution based and biomimetic methods. While each approach has its own intrinsic materials and biological properties, in general CaP coatings have the promise to improve implant biocompatibility and ultimately implant longevity.

  13. IMPLANTS' SECOND STAGE SURGERY TECHNIQUES

    Microsoft Academic Search

    Metodi Abadzhiev

    2009-01-01

    SUMMARY: The sufficiency of attached gingival (AG) around teeth and fixed restorations is a sign for absence of local traumatic factors from dental or soft-tissue origin. Nevertheless the supporters are natural teeth or implants, the attached gingiva around the restoration is a guarantee for long-term, aesthetic and functional prosthetic restora- tions. This refers particularly to the attached gingival around the

  14. He reemission implanted in metals

    NASA Astrophysics Data System (ADS)

    Tanabe, T.

    2014-10-01

    Helium (He) reemission of Al, Ni and Mo under energetic He implantation (10-30 keV) in wide temperature range is studied to understand behavior of implanted He in correlation with structure changes. The reemission behavior is categorized into 4 different temperature ranges with the normalized temperature (Tm) to the melting point of each metal. At elevated temperatures (well above ?0.6 Tm), interstitial He atoms and/or He-vacancy (ies) clusters can migrate remaining no structure change and showing smooth reemission without any burst. Between ?0.25 and 0.6 Tm, He reemission always accompanies significant structure modification. For ?04-0.6 Tm, implanted He coalesce to make bubbles and the bubbles can move to the surface. Bubble migration accompanies materials flow to the surface resulting in fuzz surface or columnar structure, depending on implantation flux. Slower bubble motion at ?0.25-0.4 prohibits the material migration. Instead the bubbles coalesce to grow large and multi-layered blistering appears as periodic reemission behavior. Below ?0.25 Tm, He migration is too slow for bubbles to grow large, but bubble density increases up to a certain fluence, where neighboring bubbles start to coalesce. Accordingly, He release is mostly caused by mechanical failure or blister rapture. With increasing fluence, all defects (bubbles and dislocation loops) tangle or inter connected with neighboring defects and accordingly He migration to the surface along the tangled or connected defects is enhanced, resulting 100% reemission easily without making multilayered blistering.

  15. [Cochlear implantation in immunocompromised patients].

    PubMed

    Go?khburg, M V; Zherenkova, V V; Chugunova, T I; Iasinskaia, A A; Bakhshinian, V V

    2014-01-01

    This paper reports a clinical case that gives evidence of the possibility of cochlear implantation after liver transplantation. Patient K. aged 3 years 10 months was admitted to the Russian Research and Practical Centre of Audiology and Hearing Rehabilitation with the diagnosis of type IB glycogenosis after maternal liver transplantation associated with chronic neutropenia, chronic cutaneous and mucosal infection, partial symptomatic partial epilepsy, retarded psycho-motor development, and complaints of the absence of auditory response. The audiological examination provided materials for the diagnosis of grade IV bilateral sensorineural hearing loss tending toward deafness. Cochlear implantation recommended to the patient was performed on February 20, 2013 using the HiRes 90 K implant with the HiFocus Helix electrode (Advanced Bionics, USA). The surgical intervention and the postoperative period passed without complications. The speech processor was activated one month after surgery. The results of surdopedagogical testing gave evidence of successful rehabilitation promising the further improvement. It is concluded that immunosuppressive therapy is not an absolute contraindication for cochlear implantation, but this procedure requires detailed examination and thorough preparation for the forthcoming surgery. PMID:24781183

  16. Ion implantation for plasma torches

    Microsoft Academic Search

    I. R. Jankov; I. D. Goldman; R. N. Szente

    2002-01-01

    It has been shown before that the erosion of a cathode is related to the condition of its surface, particularly with respect to its composition. The composition of the surface seems to affect different parameters, including the work function of the surface. We have developed a method to implant different ions on the surface of copper plates in order to

  17. Hydroxyapatite-coated tooth implants by laser

    NASA Astrophysics Data System (ADS)

    Jelinek, Miroslav; Dostalova, Tatjana; Himmlova, Lucia; Grivas, Christos

    1996-09-01

    Thin films of biocompatible ceramic were fabricated by pulsed laser deposition on cylindrical implants. Diamond- like carbon films were deposited in vacuum on titanium alloy prostheses, heated to 90 degrees C. Coated prostheses were implanted into legs of rats and osseointegration higher than 60 percent was determined. Thin films of hydroxyapatite were created on real dental implants at 500 degrees C in Ar-water vapor atmosphere. Coated implants were implanted into mandibula of minipigs to study load free osseointegration. Results and experiences are presented and discussed.

  18. [Digital implant impression taking - an overview].

    PubMed

    Mahl, Dominik; Glenz, Fabienne; Marinello, Carlo P

    2014-01-01

    In dentist's daily practice, intraoral scanning systems are increased. Besides scanning of prepared teeth, also implants could be scanned intraorally. This clinical report describes the step-by-step techniques to scan digitally intraoral implants with two intraoral scanners (Lava™ C.O.S., 3M Espe and the CEREC AC connected with inLab MC XL, Sirona) for generating implant suprastructures without the use of impression materials, dental stone or implant impression copings. Different workflows, possibilities and limits by scanning dental implants are demonstrated. PMID:24585419

  19. Magnetic resonance imaging of breast implants.

    PubMed

    Shah, Mala; Tanna, Neil; Margolies, Laurie

    2014-12-01

    Silicone breast implants have significantly evolved since their introduction half a century ago, yet implant rupture remains a common and expected complication, especially in patients with earlier-generation implants. Magnetic resonance imaging is the primary modality for assessing the integrity of silicone implants and has excellent sensitivity and specificity, and the Food and Drug Administration currently recommends periodic magnetic resonance imaging screening for silent silicone breast implant rupture. Familiarity with the types of silicone implants and potential complications is essential for the radiologist. Signs of intracapsular rupture include the noose, droplet, subcapsular line, and linguine signs. Signs of extracapsular rupture include herniation of silicone with a capsular defect and extruded silicone material. Specific sequences including water and silicone suppression are essential for distinguishing rupture from other pathologies and artifacts. Magnetic resonance imaging provides valuable information about the integrity of silicone implants and associated complications. PMID:25463409

  20. [Cochlear implantation - better safe than sorry].

    PubMed

    Vankatova, L; Cao Van, H; Perez Fornos, A; Guinarnd, N

    2014-10-01

    The benefit of cochlear implants in the mtreatent of profound bilateral sensorineural hearing loss is undeniable. In Switzerland, bilateral cochlear implantation is the treatment of choice in bilateral deafness in children. Due to the anatomical relations of the cochlea and the vestibule, vestibular function can be affected during implantation. Bilateral vestibular areflexia can significantly impair the quality of life and a child's development. Therefore, even if the theoretical risk of bilateral vestibular arefilxia after cochlear implantation is only about 1%, it must be taken into account. Vestibular function assessment must be part of the pre-implantation workup. For bilateral implantations, we recommend a sequential procedure. The second implantation will take place only if the vestibular function is preserved in the other side. PMID:25417339

  1. Formation of Wear Resistant Steel Surfaces by Plasma Immersion Ion Implantation

    SciTech Connect

    Maendl, S.; Rauschenbach, B. [Institute fuer Oberflaechenmodifizierung, 04303 Leipzig (Germany)

    2003-08-26

    Plasma immersion ion implantation (PIII) is a versatile and fast method for implanting energetic ions into large and complex shaped three-dimensional objects where the ions are accelerated by applying negative high voltage pulses to a substrate immersed in a plasma. As the line-of-sight restrictions of conventional implanters are circumvented, it results in a fast and cost-effective technology. Implantation of nitrogen at 30 - 40 keV at moderate temperatures of 200 - 400 deg. C into steel circumvents the diminishing thermal nitrogen activation encountered, e.g., in plasma nitriding in this temperature regime, thus enabling nitriding of additional steel grades. Nitride formation and improvement of the mechanical properties after PIII are presented for several steel grades, including AISI 316Ti (food industry), AISI D2 (used for bending tools) and AISI 1095 (with applications in the textile industry)

  2. Hydroxyapatite ocular implant and non-integrated implants in eviscerated patients

    PubMed Central

    Gradinaru, S; Popescu, V; Leasu, C; Pricopie, S; Yasin, S; Ciuluvica, R; Ungureanu, E

    2015-01-01

    Introduction: This study compares the outcomes and complications of hydroxyapatite ocular implant and non-integrated ocular implants following evisceration. Materials and Methods: This is a retrospective study of 90 patients who underwent evisceration for different ocular affections, in the Ophthalmology Department of the University Emergency Hospital Bucharest, between January 2009 and December 2013. The outcomes measured were conjunctival dehiscence, socket infection, implant exposure and extrusion rate. Results: Forty-three patients had the hydroxyapatite implant (coralline–Integrated Ocular Implants, USA or synthetic–FCI, France) and forty-seven received non-integrated ocular implants (24 acrylic and 23 silicone). Five cases of socket infection, thirteen cases of extrusion and two cases of conjunctival dehiscence were encountered. Conclusions: There was a higher rate of conjunctival dehiscence with hydroxyapatite ocular implant, but implant extrusion and socket infection were found in non-integrated ocular implants. PMID:25914747

  3. Decontamination of dental implant surface in peri-implantitis treatment: A literature review

    PubMed Central

    Buitrago-Vera, Pedro; Solá-Ruiz, María F.; Ferrer-García, Juan C.

    2013-01-01

    Etiological treatment of peri-implantitis aims to reduce the bacterial load within the peri-implant pocket and decontaminate the implant surface in order to promote osseointegration. The aim of this literature review was to evaluate the efficacy of different methods of implant surface decontamination. A search was conducted using the PubMed (Medline) database, which identified 36 articles including in vivo and in vitro studies, and reviews of different decontamination systems (chemical, mechanical, laser and photodynamic therapies). There is sufficient consensus that, for the treatment of peri-implant infections, the mechanical removal of biofilm from the implant surface should be supplemented by chemical decontamination with surgical access. However, more long-term research is needed to confirm this and to establish treatment protocols responding to different implant characterics. Key words:Peri-implantitis, treatment, decontamination, implant surface, laser. PMID:23986023

  4. Cochlear implants: a remarkable past and a brilliant future.

    PubMed

    Wilson, Blake S; Dorman, Michael F

    2008-08-01

    The aims of this paper are to (i) provide a brief history of cochlear implants; (ii) present a status report on the current state of implant engineering and the levels of speech understanding enabled by that engineering; (iii) describe limitations of current signal processing strategies; and (iv) suggest new directions for research. With current technology the "average" implant patient, when listening to predictable conversations in quiet, is able to communicate with relative ease. However, in an environment typical of a workplace the average patient has a great deal of difficulty. Patients who are "above average" in terms of speech understanding, can achieve 100% correct scores on the most difficult tests of speech understanding in quiet but also have significant difficulty when signals are presented in noise. The major factors in these outcomes appear to be (i) a loss of low-frequency, fine structure information possibly due to the envelope extraction algorithms common to cochlear implant signal processing; (ii) a limitation in the number of effective channels of stimulation due to overlap in electric fields from electrodes; and (iii) central processing deficits, especially for patients with poor speech understanding. Two recent developments, bilateral implants and combined electric and acoustic stimulation, have promise to remediate some of the difficulties experienced by patients in noise and to reinstate low-frequency fine structure information. If other possibilities are realized, e.g., electrodes that emit drugs to inhibit cell death following trauma and to induce the growth of neurites toward electrodes, then the future is very bright indeed. PMID:18616994

  5. Cochlear implants: a remarkable past and a brilliant future

    PubMed Central

    Wilson, Blake S.; Dorman, Michael F.

    2013-01-01

    The aims of this paper are to (i) provide a brief history of cochlear implants; (ii) present a status report on the current state of implant engineering and the levels of speech understanding enabled by that engineering; (iii) describe limitations of current signal processing strategies and (iv) suggest new directions for research. With current technology the “average” implant patient, when listening to predictable conversations in quiet, is able to communicate with relative ease. However, in an environment typical of a workplace the average patient has a great deal of difficulty. Patients who are “above average” in terms of speech understanding, can achieve 100% correct scores on the most difficult tests of speech understanding in quiet but also have significant difficulty when signals are presented in noise. The major factors in these outcomes appear to be (i) a loss of low-frequency, fine structure information possibly due to the envelope extraction algorithms common to cochlear implant signal processing; (ii) a limitation in the number of effective channels of stimulation due to overlap in electric fields from electrodes, and (iii) central processing deficits, especially for patients with poor speech understanding. Two recent developments, bilateral implants and combined electric and acoustic stimulation, have promise to remediate some of the difficulties experienced by patients in noise and to reinstate low-frequency fine structure information. If other possibilities are realized, e.g., electrodes that emit drugs to inhibit cell death following trauma and to induce the growth of neurites toward electrodes, then the future is very bright indeed. PMID:18616994

  6. Does the number of implants have any relation with peri-implant disease?

    PubMed Central

    PASSONI, Bernardo Born; DALAGO, Haline Renata; SCHULDT FILHO, Guenther; OLIVEIRA DE SOUZA, João Gustavo; BENFATTI, César Augusto Magalhães; MAGINI, Ricardo de Souza; BIANCHINI, Marco Aurélio

    2014-01-01

    Objective The aim of this study was to evaluate the relationship between the number of pillar implants of implant-supported fixed prostheses and the prevalence of periimplant disease. Material and Methods Clinical and radiographic data were obtained for the evaluation. The sample consisted of 32 patients with implant-supported fixed prostheses in function for at least one year. A total of 161 implants were evaluated. Two groups were formed according to the number of implants: G1) ?5 implants and G2) >5 implants. Data collection included modified plaque index (MPi), bleeding on probing (BOP), probing depth (PD), width of keratinized mucosa (KM) and radiographic bone loss (BL). Clinical and radiographic data were grouped for each implant in order to conduct the diagnosis of mucositis or peri-implantitis. Results Clinical parameters were compared between groups using Student's t test for numeric variables (KM, PD and BL) and Mann-Whitney test for categorical variables (MPi and BOP). KM and BL showed statistically significant differences between both groups (p<0.001). Implants from G1 – 19 (20.43%) – compared with G2 – 26 (38.24%) – showed statistically significant differences regarding the prevalence of peri-implantitis (p=0.0210). Conclusion It seems that more than 5 implants in total fixed rehabilitations increase bone loss and consequently the prevalence of implants with periimplantitis. Notwithstanding, the number of implants does not have any influence on the prevalence of mucositis. PMID:25466474

  7. Fabrication of a Maxillary Implant Retained Overdenture Using an Existing Subperiostal Implant: A Clinical Report

    PubMed Central

    Barrero, Carlos; Border, Michael B.; Bencharit, Sompop

    2011-01-01

    Subperiosteal implants used to be prescribed to partially and fully edentulous patients to restore occlusion and esthetics prior to the emergence of the more successful endosseous implants that are used today. Because subperiosteal implants had a high incidence of failure, difficulty of placement, and post-operative complications, the use of subperiosteal implants declined significantly. However, some subperiostal implants placed 20-30 years ago still survive. Little information is available in the literature on how to treat patients whose subperiosteal implants still remain. This clinical case report thereby describes a treatment for a patient with a maxillary subperiosteal implant placed 23 years ago. The patient was offered a treatment option that included surgical implant removal, bone grafting and placement of endosseous implants to support a new maxillary overdenture. This treatment plan was not feasible due to the financial constraints of the patient and the complexity of the treatment. The patient chose a more conservative treatment plan, preserving the existing implant. The existing maxillary subperiosteal implant was restored with MICRO ERA attachments and a maxillary implant-retained overdenture was fabricated. The patient was satisfied with the esthetics and functional aspects of the treatment. No further peri-implant bone loss or other complications were found after a six-month recall. This clinical report suggests an alternative treatment plan for patients with existing subperiosteal implants that wish to avoid complex surgical procedures. PMID:21804901

  8. The Educational Technology Centre: A Window to View the Progress of Chinese ICT-Based Higher Education

    ERIC Educational Resources Information Center

    Zhou, Rong; Xie, Baizhi

    2010-01-01

    In China, after many years, the current status and challenges of e-learning development in higher education have been gradually understood. The educational technology centre (ECT) serves as the key unit to promote e-learning initiatives, but the performance of some centres still trails their foreign counterparts. Under such conditions, the project…

  9. A Cost-effectiveness Analysis of Implant Overdentures

    Microsoft Academic Search

    N. U. Zitzmann; C. P. Marinello; P. Sendi

    2006-01-01

    Placement of dental implants may improve the retention and stability of complete dentures in edentulous patients. Treatment costs, however, substantially increase with implant treatment. We therefore performed a stochastic cost-effectiveness analysis, comparing implant-supported over-denture prostheses (4 implants), implant-retained overdentures (2 implants), and complete dentures, from the patient's perspective in Switzerland, to assess whether implant treatment in the mandible represents value

  10. Managing chronic pain with encapsulated cell implants releasing catecholamines and endogenous opiods.

    PubMed

    Winn, Shelley R; Emerich, Dwaine F

    2005-01-01

    Spinal injections (intrathecal) of norepinephrine and/or opiod agonists are antinociceptive and when administered together may act in synergy. Spinal implants of adrenal chromaffin cells are an effective method for sustained delivery of the analgesic substances norepinephrine and enkephalin to the central nervous system (CNS). One method of packaging and implanting cell-loaded devices into the intrathecal space of recipients is by encapsulating the cell suspensions in a polymer membrane prior to implantation. Cells/tissue packaged within an encapsulating membrane obviate the need for immunosuppressive therapies in transplant recipients. In addition, device output can be quantified prior to implantation, and following the removal of the spinal implant. The ability to retrieve the devices with the present tubular configuration also confers an additional margin of safety over unencapsulated chromaffin cell implants. This paper reviews the research and clinical observations of cellular transplants containing adrenal chromaffin cells for relieving chronic pain. Encapsulated cell technology is discussed with an emphasis on our experiences developing pain-modulating clinical devices. The human-sized prototype devices were loaded with enzymatically isolated bovine chromaffin cells and maintained in vitro for 7 - 8 days in serum-free media. Two days prior to implantation, each device was assayed by static incubation to measure catecholamine and met-enkephalin output, and qualified devices (n = 6) were implanted into the sheep subarachnoid space for 6 weeks. Following a 6 week in life period, the retrieval forces of prototype devices were measured during removal from the subarachnoid space. Static incubation of the devices immediately following retrieval and after a 24 hour re-incubation period were used to quantify norepinephrine and met-enkephalin secretion profiles. This study demonstrated the safety, retrievability and maintenance of pharmacologically active encapsulated chromaffin cell-loaded devices with human implant dimensions. PMID:15574375

  11. SIMS study of TiN carbon implanted at high-fluences

    NASA Astrophysics Data System (ADS)

    Mello, D.; Mirenghi, L.; Falcone, R.; Esposito, C.

    2004-11-01

    Ion implantation of titanium nitrite (TiN) coatings attracts a great deal of attention because of the improvement of tribological resistance of the coating surface. In this work we have analysed implanted TiN films by using secondary ion mass spectrometry (SIMS). Coatings with a thickness of about 4 ?m were implanted with C+ at energies of 100 keV and fluences ranging from 1016 to 7 × 1017 ions/cm2. The experiments were performed on commercial TiN films prepared by physical vapour deposition (PVD) on hard metal tools. If reactive elements, like C or N, are implanted to significative fluences, the implant concentration (say greater than 1 at.%) could induce a distortion in the experimental elemental profiles because of a change in the sputtering yield and/or the ionisation probability (matrix effects). While the first point has been shown to be largely insignificant, the second is studied in more detail. In the case of carbon implanted in TiN the influence of matrix effects on the secondary ion signals can be minimised if a primary beam of Cs+ and secondary negative ions are chosen for depth profiling up to fluences of technological interest, say 3 × 1017 ions/cm2. In this way the concentration changes induced in the ion implanted region can be quantified. Linear calibration curves were obtained for an accurate quantification and X-ray photoelectron spectroscopy (XPS) was employed to extract the starting stoichiometry in the unimplanted TiN film and to assess the chemical state along the depth profiles in the implanted samples. After implantation a swelling of the films was observed and has been discussed. SIMS profiles were measures both by cesium and oxygen primary beams.

  12. Analysis and evalaution in the production process and equipment area of the low-cost solar array project. [including modifying gaseous diffusion and using ion implantation

    NASA Technical Reports Server (NTRS)

    Goldman, H.; Wolf, M.

    1979-01-01

    The manufacturing methods for photovoltaic solar energy utilization are assessed. Economic and technical data on the current front junction formation processes of gaseous diffusion and ion implantation are presented. Future proposals, including modifying gaseous diffusion and using ion implantation, to decrease the cost of junction formation are studied. Technology developments in current processes and an economic evaluation of the processes are included.

  13. In-Plane Biocompatible Microfluidic Interconnects for Implantable Microsystems

    PubMed Central

    Johnson, Dean G.; Frisina, Robert D.; Borkholder, David A.

    2011-01-01

    Small mammals, particularly mice, are very useful animal models for biomedical research. Extremely small anatomical dimensions, however, make design of implantable microsystems quite challenging. A method for coupling external fluidic systems to microfluidic channels via in-plane interconnects is presented. Capillary tubing is inserted into channels etched in the surface of a Si wafer with a seal created by Parylene-C deposition. Prediction of Parylene-C deposition into tapered channels based on Knudsen diffusion and deposition characterizations allows for design optimization. Low-volume interconnects using biocompatible, chemical resistant materials have been demonstrated and shown to withstand pressure as high as 827 kPa (120 psi) with an average pull test strength of 2.9 N. Each interconnect consumes less than 0.018 mm3 (18 nL) of volume. The low added volume makes this an ideal interconnect technology for medical applications where implant volume is critical. PMID:21147591

  14. A woman's experience: living with an implantable cardioverter defibrillator.

    PubMed

    Conelius, Jaclyn

    2015-05-01

    The implantable cardioverter defibrillators (ICD) have decreased mortality rates from those who are at risk for sudden cardiac death or who have survived sudden cardiac death and has been shown to be superior to anti-arrhythmic medications (Greenburg et al., 2004). This advance in technology may improve physical health but can impose some challenges to patients, such as depression, anxiety, fear, and unpredictability. Published research on how ICD affects a woman's life experience using phenomenology is limited. Therefore, the purpose of this article is to describe the experiences of women who have an ICD using Colaizzi's method of phenomenology since their implant. Analysis of the three interviews resulted in five themes that described the essence of this experience. The results of this study could not only help clinicians understand what their patients are experiencing but also it can be used as an education tool. PMID:25481839

  15. NASA's Van Allen Probes RBSP-ECT Data Products and Access to Them: An Insider's Outlook on the Inner and Outer Belts (and We Don't Mean the Nation's Beltway...)

    NASA Astrophysics Data System (ADS)

    Smith, S. S.; Friedel, R. H. W.; Henderson, M. G.; Larsen, B.; Reeves, G. D.; Spence, H. E.

    2014-12-01

    In this poster, we present a summary of access to the data products of the Radiation Belt Storm Probes - Energetic Particle Composition, and Thermal plasma (RBSP-ECT) suite of NASA's Van Allen Probes mission. The RBSP-ECT science investigation (http://rbsp-ect.sr.unh.edu) measures comprehensively the near-Earth charged particle environment in order to understand the processes that control the acceleration, global distribution, and variability of radiation belt electrons and ions. RBSP-ECT data products derive from the three instrument elements that comprise the suite, which collectively covers the broad energies that define the source and seed populations, the core radiation belts, and also their highest energy ultra-relativistic extensions. These RBSP-ECT instruments include, from lowest to highest energies: the Helium, Oxygen, Proton, and Electron (HOPE) sensor, the Magnetic Electron and Ion Spectrometer (MagEIS), and the Relativistic Electron and Proton Telescope (REPT). We provide a brief overview of their principles of operation, as well as a description of the Level 1-3 data products that the HOPE, MagEIS, and REPT instruments produce, both separately and together. We provide a summary of how to access these RBSP-ECT data products at our Science Operation Center and Science Data Center (http://www.rbsp-ect.lanl.gov/rbsp_ect.php ) as well as caveats for their use. Finally, in the spirit of efficiently and effectively promoting and encouraging new collaborations, we present a summary of past publications, current studies, and opportunities for your future participation in RBSP-ECT science analyses.

  16. Subgingival microbiome in patients with healthy and ailing dental implants.

    PubMed

    Zheng, Hui; Xu, Lixin; Wang, Zicheng; Li, Lianshuo; Zhang, Jieni; Zhang, Qian; Chen, Ting; Lin, Jiuxiang; Chen, Feng

    2015-01-01

    Dental implants are commonly used to replace missing teeth. However, the dysbiotic polymicrobial communities of peri-implant sites are responsible for peri-implant diseases, such as peri-implant mucositis and peri-implantitis. In this study, we analyzed the microbial characteristics of oral plaque from peri-implant pockets or sulci of healthy implants (n?=?10), peri-implant mucositis (n?=?8) and peri-implantitis (n?=?6) sites using pyrosequencing of the 16S rRNA gene. An increase in microbial diversity was observed in subgingival sites of ailing implants, compared with healthy implants. Microbial co-occurrence analysis revealed that periodontal pathogens, such as Porphyromonas gingivalis, Tannerella forsythia, and Prevotella intermedia, were clustered into modules in the peri-implant mucositis network. Putative pathogens associated with peri-implantitis were present at a moderate relative abundance in peri-implant mucositis, suggesting that peri-implant mucositis an important early transitional phase during the development of peri-implantitis. Furthermore, the relative abundance of Eubacterium was increased at peri-implantitis locations, and co-occurrence analysis revealed that Eubacterium minutum was correlated with Prevotella intermedia in peri-implantitis sites, which suggests the association of Eubacterium with peri-implantitis. This study indicates that periodontal pathogens may play important roles in the shifting of healthy implant status to peri-implant disease. PMID:26077225

  17. Subgingival microbiome in patients with healthy and ailing dental implants

    PubMed Central

    Zheng, Hui; Xu, Lixin; Wang, Zicheng; Li, Lianshuo; Zhang, Jieni; Zhang, Qian; Chen, Ting; Lin, Jiuxiang; Chen, Feng

    2015-01-01

    Dental implants are commonly used to replace missing teeth. However, the dysbiotic polymicrobial communities of peri-implant sites are responsible for peri-implant diseases, such as peri-implant mucositis and peri-implantitis. In this study, we analyzed the microbial characteristics of oral plaque from peri-implant pockets or sulci of healthy implants (n?=?10), peri-implant mucositis (n?=?8) and peri-implantitis (n?=?6) sites using pyrosequencing of the 16S rRNA gene. An increase in microbial diversity was observed in subgingival sites of ailing implants, compared with healthy implants. Microbial co-occurrence analysis revealed that periodontal pathogens, such as Porphyromonas gingivalis, Tannerella forsythia, and Prevotella intermedia, were clustered into modules in the peri-implant mucositis network. Putative pathogens associated with peri-implantitis were present at a moderate relative abundance in peri-implant mucositis, suggesting that peri-implant mucositis an important early transitional phase during the development of peri-implantitis. Furthermore, the relative abundance of Eubacterium was increased at peri-implantitis locations, and co-occurrence analysis revealed that Eubacterium minutum was correlated with Prevotella intermedia in peri-implantitis sites, which suggests the association of Eubacterium with peri-implantitis. This study indicates that periodontal pathogens may play important roles in the shifting of healthy implant status to peri-implant disease. PMID:26077225

  18. Implantable vaccine development using in vitro antigen-pulsed macrophages absorbed on laser micro-structured Si scaffolds.

    PubMed

    Zerva, Ioanna; Simitzi, Chara; Siakouli-Galanopoulou, Alexandra; Ranella, Anthi; Stratakis, Emmanuel; Fotakis, Costas; Athanassakis, Irene

    2015-06-17

    To overcome the limiting antigenic repertoire of protein sub-units and the side effects of adjuvants applied in second generation vaccines, the present work combined in vitro and in vivo manipulations to develop biomaterials allowing natural antigen-loading and presentation in vitro and further activation of the immune response in vivo. 3-dimensional laser micro-textured implantable Si-scaffolds supported mouse macrophage adherence, allowed natural seeding with human serum albumin (antigen) and specific antibody and inflammatory cytokine production in vitro. Implantation of Si-scaffolds loaded with antigen-activated macrophages induced an inflammatory reaction along with antigen-specific antibody production in vivo, which could be detected even 30 days post implantation. Analysis of implant histology using scanning electron microscopy showed that Si-scaffolds could be stable for a 6-month period. Such technology leads to personalized implantable vaccines, opening novel areas of research and treatment. PMID:25979803

  19. Retinal Implants: Emergence of a multidisciplinary field

    PubMed Central

    2012-01-01

    Purpose of review To summarize the current status of retinal prostheses, recent accomplishments, and major remaining research, engineering, and rehabilitation challenges. Recent findings Retinal research, materials and biocompatibility studies, and clinical trials in patients blind from RP are representative of an emerging field with considerable promise and sobering challenges. A summary of progress in dozens of labs, companies, and clinics around the world is presented through a synopsis of relevant papers, not only to summarize the progress, but also to convey the remarkable increase in interest, effort, and outside funding this field has enjoyed. Summary At the present time, clinical applications of retinal implant technology are dominated by one or two groups/companies, but the field is wide open for others to take the lead through novel approaches in technology, tissue interfacing, information transfer paradigms, and rehabilitation. Where the field will go in the next few years is almost anybody’s guess, but that it will move forward is a certainty. PMID:22185902

  20. Cost drivers in total hip arthroplasty: effects of procedure volume and implant selling price.

    PubMed

    Kelly, Michael P; Bozic, Kevin J

    2009-01-01

    Total hip arthroplasty (THA), though a highly effective procedure for patients with end-stage hip disease, has become increasingly costly, both because of increasing procedure volume and because of the introduction and widespread use of new technologies. Data regarding procedure volume and procedure costs for THA were obtained from the National Inpatient Sample and other published sources for the years 1995 through 2005. Procedure volume increased 61% over the period studied. When adjusted for inflation, using the medical consumer price index, the average selling price of THA implants increased 24%. The selling price of THA implants as a percentage of total procedure costs increased from 29% to 60% during the period under study. The increasing cost of THA in the United States is a result of both increased procedure volume and increased cost of THA implants. No long-term outcome studies related to use of new implant technologies are available, and short-term results have been similar to those obtained with previous generations of THA implants. This study reinforces the need for a US total joint arthroplasty registry and for careful clinical and economic analyses of new technologies in orthopedics. PMID:19238268

  1. Combining dissimilar metals in orthopaedic implants: revisited.

    PubMed

    Zartman, Kevin C; Berlet, Gregory C; Hyer, Christopher F; Woodard, Joseph R

    2011-10-01

    The use of metals as implant materials has become common practice in the field of orthopaedics. A wide variety of conditions are treated with metallic implants, and designers have used an assortment of materials to meet the unique mechanical demands of each application. The majority of implants used today, whether pins, plates, screws, or total joints, are made of cobalt-chrome alloy, stainless steel, or titanium. Common metallurgic wisdom cautions against bonding dissimilar metals in a biologically active environment. Surgeons have therefore shied away from combining dissimilar metal implants because of the fear of inciting corrosion that could potentially compromise the implants and lead to aseptic loosening, implant failure, or adverse biological reaction in host tissue. As surgical reconstruction and arthroplasty options expand with the advent of newer implants and expanded operative techniques, the orthopaedic surgeon will increasingly be faced with weighing the risks and benefits of combining implants made of dissimilar metals in a patient. Here, the authors examine the origins of the concern over using mixed metals, discuss mechanisms of corrosion as they relate to surgical implants, and review both in vitro and in vivo studies concerning the most common combinations of dissimilar metals in order to guide the surgeon in choosing implants. PMID:21926357

  2. Miniscrew implant applications in contemporary orthodontics.

    PubMed

    Chang, Hong-Po; Tseng, Yu-Chuan

    2014-03-01

    The need for orthodontic treatment modalities that provide maximal anchorage control but with minimal patient compliance requirements has led to the development of implant-assisted orthodontics and dentofacial orthopedics. Skeletal anchorage with miniscrew implants has no patient compliance requirements and has been widely incorporated in orthodontic practice. Miniscrew implants are now routinely used as anchorage devices in orthodontic treatment. This review summarizes recent data regarding the interpretation of bone data (i.e., bone quantity and quality) obtained by preoperative diagnostic computed tomography (CT) or by cone-beam computed tomography (CBCT) prior to miniscrew implant placement. Such data are essential when selecting appropriate sites for miniscrew implant placement. Bone characteristics that are indications and contraindications for treatment with miniscrew implants are discussed. Additionally, bicortical orthodontic skeletal anchorage, risks associated with miniscrew implant failure, and miniscrew implants for nonsurgical correction of occlusal cant or vertical excess are reviewed. Finally, implant stability is compared between titanium alloy and stainless steel miniscrew implants. PMID:24581210

  3. Cochlear Implant Using Neural Prosthetics

    NASA Astrophysics Data System (ADS)

    Gupta, Shweta; Singh, Shashi kumar; Dubey, Pratik Kumar

    2012-10-01

    This research is based on neural prosthetic device. The oldest and most widely used of these electrical, and often computerized, devices is the cochlear implant, which has provided hearing to thousands of congenitally deaf people in this country. Recently, the use of the cochlear implant is expanding to the elderly, who frequently suffer major hearing loss. More cutting edge are artificial retinas, which are helping dozens of blind people see, and ìsmartî artificial arms and legs that amputees can maneuver by thoughts alone, and that feel more like real limbs.Research, which curiosity led to explore frog legs dancing during thunderstorms, a snail shapedorgan in the inner ear, and how various eye cells react to light, have fostered an understanding of how to ìtalkî to the nervous system. That understanding combined with the miniaturization of electronics and enhanced computer processing has enabled prosthetic devices that often can bridge the gap in nerve signaling that is caused by disease or injury.

  4. [Mammary implants and breast cancer].

    PubMed

    Meunier, A; Tristant, H; Sinna, R; Delay, E

    2005-10-01

    Many publications deal with the impact of cosmetic breast implants to increase the breast cancer occurence or to delay its diagnosis. We first try to express the clinical and radiological differences in the implanted breast. The diagnostical and therapeutical difficulties were developped to the different technics of imagery, biopsy and specific management of the treatment. On one hand, the litterature revue does not show any significant difference in tumoral stage and nodal status between augmented and nonaugmented women eventhough the mammography sensibility is not as optimal. On the other hand, the global mortality of the augmented population is higher but it appears that this phenomenon could be link to their way of life and is totally independant of breast cancer. Finally, if the diagnosis and the treatment are more complex, the women survival is not altered by breast augmented surgery. PMID:16169139

  5. Backing up Medium Current Implanters using Single Wafer High Energy Implanter for Manufacturing Efficiency

    NASA Astrophysics Data System (ADS)

    Sun, H. L.; Lee, Woojin; Xu, Knight; Tsun, H. Y.; Peng, K. T.; Juang, L. S.; Tseng, H. P.

    2006-11-01

    Today most high volume manufacturing fabs are experiencing an inefficient distribution of resources between medium current (MC) and high energy (HE) implanters. The utilization levels of medium current implanters and high energy implanters differ greatly due to increasing amounts of medium current implant recipes. Medium current implanters are very highly utilized, while high energy implanters are not used as much. Thus, the high energy implant tools can be used to optimize manufacturing efficiency and production cost reduction by backing up the medium current tools. Traditionally, there were only well implants that can be processed on both single wafer medium current (SWMC) and batch HE implanters. However, by using the Varian VIISta 3000HP Single Wafer High Energy implanter (SWHE) with high tilt and true zero degree implantation capability, Vt, anti-punch-through and pocket/ halo implants can also be used as backups. The data of the electrical function and yield comparison between SWHE VIISta 3000HP and SWMC EHP500 was shown to be compatible. The throughput was also evaluated to match the productivity of medium current implanters which are higher than the batch tools. This paper shows that the SWHE can maximize the manufacturing efficiency and minimize the production cost.

  6. Implantable telemetry for small animals

    NASA Technical Reports Server (NTRS)

    1982-01-01

    A series of totally implantable telemetry devices for use in measuring deep body parameters in small animals were developed. Under a collaborative agreement with NASA, several of these systems; the continuous wave Doppler ultrasonic flowmeter, the multichannel telemetry system, and the inductively-powered dual channel cardiac pacer were evaluated in a series of ten mongrel dogs (15 to 20 kg.). These systems were used to measure ascending aortic and coronary blood flow, aortic pressure, and subcutaneous EKG.

  7. Carbon nanotubes for orthopaedic implants

    Microsoft Academic Search

    Rose L. Spear; Ruth E. Cameron

    2008-01-01

    The physical and biological limitations of current orthopaedic implant materials are a major challenge for bone tissue engineering.\\u000a Nanotechnology has introduced new materials and methods for meeting this challenge. The application of nanotechnology to engineering\\u000a new bone substitutes finds a model in the nanoscale components of natural bone tissue. Carbon nanotubes are a macromolecular\\u000a form of carbon with exceptional properties

  8. Biostability of materials and implants.

    PubMed

    Bruck, S D

    1991-01-01

    The purpose of this paper is to discuss some important parameters that are involved in the biostability of materials and implants aimed at the eventual development of improved in vitro testing and evaluation procedures. In view of the fact that certain terms have been the subject of misunderstandings, definitions are offered for the terms "biomaterials", "bioerosion", "biostability", and "bioresorption". Following brief descriptions of various classes of materials used in biomedical applications, the in vitro and in vivo degradations of selected materials are discussed. The main conclusions are as follows: (1) most synthetic polymers degrade in vivo by nonenzymatic hydrolysis. Hence, it is recommended that initial, in vitro testing schemes of most synthetic polymers and implants omit the use of enzyme solutions. The use of enzyme solutions is appropriate in the case of natural biopolymers as well as synthetic biodegradable polymers that contain peptidic-, glycosidic-, or phosphatidic bonds. (2) The biostability of materials and implants may be greatly affected by the simultaneous presence of stresses and active components in the physiologic environment that may lead to environmental stress cracking. (3) The biostability of polymeric materials is influenced not only by adsorption but also by the absorption of components in the physiologic environment. PMID:10171109

  9. Percolation in implanted Si film

    NASA Astrophysics Data System (ADS)

    Hiraiwa, Atsushi; Kobayashi, Takashi

    1991-07-01

    The conductivity degradation of implanted Si film has been characterized by nuclear-deposited energy independently of implant conditions. The conductivity decreases as a result of the carrier density change for the nuclear-deposited energy En ? 1 × 1023 eV/cm3, and becomes zero with mobility for En = 2.5 × 1024 eV/cm3. These results have been investigated by the percolation theory with the assistance of the Kinchin-Pease theory. The decrease in carrier density is a result of carrier trapping by vacancy-related defects. The mobility becomes zero when the nondamaged Si cluster is localized by a heavy implantation. The calculation using the site percolation is in good agreement with the experiments, where 0.428 is assumed as the percolation threshold, and 2 as the conductivity exponent. The Si displacement energy obtained is 25 eV by comparing the theory with the experiments. The experimental results suggest that microscopically conductive domains exist even in films that are macroscopically insulating.

  10. Tissue response to peritoneal implants

    NASA Technical Reports Server (NTRS)

    Picha, G. J.

    1980-01-01

    Peritoneal implants were fabricated from poly 2-OH, ethyl methacrylate (HEMA), polyetherurethane (polytetramethylene glycol 1000 MW, 1,4 methylene disocynate, and ethyl diamine), and untreated and sputter treated polytetrafluoroethylene (PTFE). The sputter treated PTFE implants were produced by an 8 cm diameter argon ion source. The treated samples consisted of ion beam sputter polished samples, sputter etched samples (to produce a microscopic surface cone texture) and surface pitted samples (produced by ion beam sputtering to result in 50 microns wide by 100 microns deep square pits). These materials were implanted in rats for periods ranging from 30 minutes to 14 days. The results were evaluated with regard to cell type and attachment kinetics onto the different materials. Scanning electron microscopy and histological sections were also evaluated. In general the smooth hydrophobic surfaces attracted less cells than the ion etched PTFE or the HEMA samples. The ion etching was observed to enhance cell attachment, multinucleated giant cell (MNGC) formation, cell to cell contact, and fibrous capsule formation. The cell responsed in the case of ion etched PTFE to an altered surface morphology. However, equally interesting was the similar attachment kinetics of HEMA verses the ion etched PTFE. However, HEMA resulted in a markedly different response with no MNGC's formation, minimal to no capsule formation, and sample coverage by a uniform cell layer.

  11. Bilateral Cochlear Implants in Children: Localization Acuity Measured with Minimum

    E-print Network

    Litovsky, Ruth

    Bilateral Cochlear Implants in Children: Localization Acuity Measured with Minimum Audible Angle participated, 13 with BI cochlear implants (cochlear implant co- chlear implant), ranging in age from 3 to 16 yrs, and six with a hearing aid in the nonimplanted ear (cochlear implant hearing aid), ages 4 to 14

  12. Immediate implants in anterior maxillary arch

    PubMed Central

    Anitha, K.; Kumar, S. Senthil; Babu, M. R. Ramesh; Candamourty, Ramesh; Thirumurugan

    2014-01-01

    Aim: The aim of the study was to evaluate the osseo-integration and soft tissue status of the endosseous implants placed in immediate extraction socket. Methodology: Seven patients (4 males and 3 females) aged 20-30 years were selected for the study. Nine implants were placed in seven patients in the maxillary arch. All the patients were clinically ?nd thoroughly examined. Under local anesthesia, the indicated tooth was extracted. The extracted socket was prepared using standard drills with palatal wall as guide. The longest and widest implants were placed (Hi-Tec Implants). All implants showed good primary stability. The implants used in the study were tapered design endosseous implants with Threaded implants (TI) unit plasma-sprayed surface. Surgical re-entry (secondary surgery) was performed to remove the healing cap after 6 months for supra crestal fabrication. All patients were reviewed periodically at 3rd and 6th month interval and the following clinical parameters including modified plaque index (mPlI), modified bleeding index (mBI), probing depth (PD), attachment level (AL), and distance between the implant shoulder and mucosal margin (DIM), distance between the implant shoulder and first bone-implant contact, and Clinical Mobility Index were recorded. The results were computed and subjected to statistical evaluation. Results: The mPlI, mBI, PD, AL, and DIM were evaluated around the implants at baseline, 3rd and 6th month intervals and analyzed statistically by Friedman T-test. The results of the above were shown to be statistically non-significant. The distance between the implant shoulder and first bone implant contact was evaluated around the implants at base line, 3rd and 6th month intervals. The results proved to be statistically significant (0.01) implying that there was a bone apposition around the implants. Conclusion: During the course of the study, soft tissue status around implants was found to be healthy. Osseointegration as assessed by clinical and radiographic findings was found to be sound. PMID:24678203

  13. Patients, Pacemakers, and Implantable Defibrillators: Human Values and Security for Wireless Implantable

    E-print Network

    Anderson, Richard

    Implantable Medical Devices Tamara Denning , Alan Borning , Batya Friedman , Brian T. Gill , Tadayoshi Kohno of Washington Department of Mathematics, Seattle Pacific University + Medical Device Safety Institute, Beth Israel Deaconess Medical Center Harvard Medical School ABSTRACT Implantable medical devices (IMDs

  14. Treatment strategies for infraoccluded dental implants.

    PubMed

    Zitzmann, Nicola U; Arnold, Dario; Ball, Judith; Brusco, Daniel; Triaca, Albino; Verna, Carlalberta

    2015-03-01

    Single-tooth implants in the maxillary anterior region have the highest risk of esthetic complications from infrapositioning due to continuing maxillary growth and the eruption of adjacent teeth. Although the placement of anterior single-tooth implants should normally be postponed, particularly girls and young women with a hyperdivergent growth pattern, if an infraposition of an implant is present, then thorough examination and strategic planning are required. According to the severity, the strategic treatment options are as follows: simple retention; adjustment or replacement of the implant restoration, possibly including adjacent teeth; surgical implant repositioning by segmental osteotomy combined with osseodistraction; or submergence or removal of the implant. With the patient presented, an interdisciplinary approach that combined orthodontic alignment, surgical segmental osteotomy, distraction osteogenesis, and restorative features offered the opportunity to realign the adjacent teeth into the arch and to harmonize the gingival contour by means of continuous soft tissue enlargement and adaptation. PMID:25444288

  15. The Bone-Forming Effects of HIF-1?-Transduced BMSCs Promote Osseointegration with Dental Implant in Canine Mandible

    PubMed Central

    Zou, Duohong; He, Jiacai; Zhang, Kai; Dai, JieWen; Zhang, Wenjie; Wang, Shaoyi; Zhou, Jian; Huang, Yuanliang

    2012-01-01

    The presence of insufficient bone volume remains a major clinical problem for dental implant placement to restore the oral function. Gene-transduced stem cells provide a promising approach for inducing bone regeneration and enhancing osseointegration in dental implants with tissue engineering technology. Our previous studies have demonstrated that the hypoxia-inducible factor-1? (HIF-1?) promotes osteogenesis in rat bone mesenchymal stem cells (BMSCs). In this study, the function of HIF-1? was validated for the first time in a preclinical large animal canine model in term of its ability to promote new bone formation in defects around implants as well as the osseointegration between tissue-engineered bone and dental implants. A lentiviral vector was constructed with the constitutively active form of HIF-1? (cHIF). The ectopic bone formation was evaluated in nude mice. The therapeutic potential of HIF-1?-overexpressing canine BMSCs in bone repair was evaluated in mesi-implant defects of immediate post-extraction implants in the canine mandible. HIF-1? mediated canine BMSCs significantly promoted new bone formation both subcutaneously and in mesi-implant defects, including increased bone volume, bone mineral density, trabecular thickness, and trabecular bone volume fraction. Furthermore, osseointegration was significantly enhanced by HIF-1?-overexpressing canine BMSCs. This study provides an important experimental evidence in a preclinical large animal model concerning to the potential applications of HIF-1? in promoting new bone formation as well as the osseointegration of immediate implantation for oral function restoration. PMID:22403648

  16. Implant Supported Distal Extension over Denture Retained by Two Types of Attachments. A Comparative Radiographic Study by Cone Beam Computed Tomography

    PubMed Central

    Mahrous, Ahmed I; Aldawash, Hussien A; Soliman, Tarek A; Banasr, Fahad H; Abdelwahed, Ahmed

    2015-01-01

    Background: This study was conducted to compare and evaluate the effect of two different attachments (locator attachment and ball and socket [B&S] attachment) on implants and natural abutments supporting structures, in cases of limited inter-arch spaces in mandibular Kennedy Class I implant supported removable partial over dentures by measuring the bone height changes through the cone beam radiographic technology. Materials and Methods: Two implants were positioned in the first or second molar area following the two-stage surgical protocol. Two equal groups were divided ten for each: Group I: Sides were the placed implants restored by the locator attachment. Group II: The other sides, implants were restored by B&S attachment. Evaluation of the implants and main abutments supporting structures of each group was done at the time of removable partial over denture insertion, 6, 12 and 18 months by measuring the bone height changes using cone beam computed tomography. Results: Implants with locator attachment showed marginal bone height better effects on implants and main abutments supporting structures. Conclusion: Implants restored by locator attachment shows better effects on bone of both main natural abutments and implant than those restored with ball and socket. PMID:26028894

  17. Atypical failure after cochlear implantation in children.

    PubMed

    Wartelle, S; Blanchard, M; Thierry, B; Parodi, M; Rouillon, I; Garabedian, E N; Loundon, N

    2014-08-01

    We report a case of intermittent dysfunction in a 10-years-old boy, implanted with MedEL(®) cochlear implant. Few weeks after the surgery the boy described short and intermittent episodes of implant dysfunction with rapid return to a normal function. No evidence for any electric or neural dysfunction was found. After few weeks, a clinical link was discovered to episodes of sneeze or nose blowing. Clinical and surgical implications are discussed. PMID:24974146

  18. Viscoelastic properties of a synthetic meniscus implant.

    PubMed

    Shemesh, Maoz; Asher, Roy; Zylberberg, Eyal; Guilak, Farshid; Linder-Ganz, Eran; Elsner, Jonathan J

    2014-01-01

    There are significant potential advantages for restoration of meniscal function using a bio-stable synthetic implant that combines long-term durability with a dependable biomechanical performance resembling that of the natural meniscus. A novel meniscus implant made of a compliant polycarbonate-urethane matrix reinforced with high modulus ultrahigh molecular weight polyethylene fibers was designed as a composite structure that mimics the structural elements of the natural medial meniscus. The overall success of such an implant is linked on its capability to replicate the stress distribution in the knee over the long-term. As this function of the device is directly dependent on its mechanical properties, changes to the material due to exposure to the joint environment and repeated loading could have non-trivial influences on the viscoelastic properties of the implant. Thus, the goal of this study was to measure and characterize the strain-rate response, as well as the viscoelastic properties of the implant as measured by creep, stress relaxation, and hysteresis after simulated use, by subjecting the implant to realistic joint loads up to 2 million cycles in a joint-like setting. The meniscus implant behaved as a non-linear viscoelastic material. The implant underwent minimal plastic deformation after 2 million fatigue loading cycles. Under low compressive loads, the implant was fairly flexible, and able to deform relatively easily (E=120-200 kPa). However as the compressive load applied on the implant was increased, the implant became stiffer (E=3.8-5.2 MPa), to resist deformation. The meniscus implant appears well-matched to the viscoelastic properties of the natural meniscus, and importantly, these properties were found to remain stable and minimally affected by potentially degradative and loading conditions associated with long-term use. PMID:24055793

  19. Bone morphogenic protein: application in implant dentistry.

    PubMed

    Bowler, Dustin; Dym, Harry

    2015-04-01

    Alveolar bone that is insufficient to support implant placement due to lack of height or width may be augmented with grafting materials including bone morphogenic protein to create sites that are adequate for implant placement and long-term stability of implant-supported prosthesis. Bone morphogenic protein can be used alone or in concert with other bone graft materials as an alternative to invasive allograft bone harvesting procedures. PMID:25835805

  20. Microgrooved silicone subcutaneous implants in guinea pigs

    Microsoft Academic Search

    X. F Walboomers; J. A Jansen

    2000-01-01

    Cell–substratum interactions are of fundamental importance for the reaction of body tissues to surgically implanted foreign materials. In our study we investigated the influence of 2?m wide microgrooves, with various depths (0.5–6?m), on capsule formation around subcutaneous silicone implants, in an animal experiment. Silicone sheets with microtexture were glued around silicone tubes. These implants were placed subcutaneously in eight guinea

  1. Pulsed source ion implantation apparatus and method

    DOEpatents

    Leung, K.N.

    1996-09-24

    A new pulsed plasma-immersion ion-implantation apparatus that implants ions in large irregularly shaped objects to controllable depth without overheating the target, minimizing voltage breakdown, and using a constant electrical bias applied to the target. Instead of pulsing the voltage applied to the target, the plasma source, for example a tungsten filament or a RF antenna, is pulsed. Both electrically conducting and insulating targets can be implanted. 16 figs.

  2. Subpectoral and Precapsular Implant Repositioning Technique: Correction of Capsular Contracture and Implant Malposition

    Microsoft Academic Search

    Hong Ki Lee; Ung Sik Jin; Yoon Ho Lee

    Background  Although capsule formation is a natural-healing process following breast augmentation using implants, a contracted capsule\\u000a around a poorly positioned implant can act as an obstacle during the corrective procedure to reposition the implant. The ideal\\u000a treatment of capsular contracture is removal of the capsule and covering the implant with a healthy envelope without scar\\u000a tissue. However, total capsulectomy in the

  3. What is a cochlear implant? A cochlear implant is an electronic device designed to convey auditory information including speech

    E-print Network

    O'Toole, Alice J.

    · What is a cochlear implant? A cochlear implant is an electronic device designed to convey). The cochlear implant system consists of an internal device that is surgically implanted into the inner ear to be meaningful for them. A cochlear implant may provide sound information for these children. · How does

  4. Fig. 1. (a) Cochlea implant system and (b) Cochlea anatomy Abstract--Robot-assisted cochlear implant surgery was

    E-print Network

    Simaan, Nabil

    --Robot-assisted cochlear implant surgery was proposed and proved to be efficient in reducing insertion forces on acrylic implant surgeries. I. INTRODUCTION ULTI-CHANNEL cochlear implants have been developed for more than 30 cochlear implant surgery. The cochlear implant system includes a microphone, a micro

  5. Domination game: e#ect of edge and vertexremoval Bostjan Bresar a,d Paul Dorbec b Sandi Klavzar c,a,d

    E-print Network

    Klavzar, Sandi

    Domination game: e#ect of edge­ and vertex­removal BoŸstjan BreŸsar a,d Paul Dorbec b Sandi Klav and Mechanics, Ljubljana, Slovenia Abstract The domination game is played on a graph G by two players, named of vertices dominated before the move on it. Dominator's goal is that the game is finished as soon as possible

  6. Domination game: e#ect of edge and vertexremoval Bostjan Bresar a Paul Dorbec b Sandi Klavzar c,a Gasper Kosmrlj c

    E-print Network

    Klavzar, Sandi

    Domination game: e#ect of edge­ and vertex­removal BoŸstjan BreŸsar a Paul Dorbec b Sandi Klav sandi.klavzar@fmf.uni­lj.si gasper.kosmrlj@student.fmf.uni­lj.si Abstract The domination game is played is that the game is finished as soon as possible, while Staller wants the game to last as long as possible

  7. E ICE TR A N S. EL ECT RON -, VOL E 89C, NO.1O0 CT0 BER 2006 SHah-w ER

    E-print Network

    Choi, Woo-Young

    E ICE TR A N S. EL ECT RON -, VOL E 89éC, NO.1O0 CT0 BER 2006 1454 SHah-×w ¹ÚÝÂER A 0.18 p m CNgo for B ack pla te Ser ial L ink K iH yuk L E V a), J ae-W ook L E E èè, N - Hm-embers, and W oo-Young CH

  8. Physical modification of polyetheretherketone for orthopedic implants

    NASA Astrophysics Data System (ADS)

    Du, Ya-Wei; Zhang, Li-Nan; Hou, Zeng-Tao; Ye, Xin; Gu, Hong-Sheng; Yan, Guo-Ping; Shang, Peng

    2014-12-01

    Polyetheretherketone (PEEK) is regarded as one of the most potential candidates for replacing current implant applications. To obtain good bone-implant interfaces, many modification methods have been developed to enable PEEK and PEEK-based composites from bio-inert to bioactive. Among them, physical methods have aroused significant attention and been widely used to modify PEEK for orthopedic implants. This review summarizes current physical modification techniques of PEEK for orthopedic applications, which include composite strategies, surface coating methods and irradiation treatments. The positive consequences of those modification methods will encourage continuing investigations and stimulate the wide range of applications of PEEK-based implants in orthopedics.

  9. Basic concepts and techniques of dental implants.

    PubMed

    Tagliareni, Jonathan M; Clarkson, Earl

    2015-04-01

    Dental implants provide completely edentulous and partial edentulous patients the function and esthetics they had with natural dentition. It is critical to understand and apply predictable surgical principles when treatment planning and surgically restoring edentulous spaces with implants. This article defines basic implant concepts that should be meticulously followed for predictable results when treating patients and restoring dental implants. Topics include biological and functional considerations, biomechanical considerations, preoperative assessments, medical history and risk assessments, oral examinations, radiographic examinations, contraindications, and general treatment planning options. PMID:25835792

  10. Implant rehabilitation for atrophic maxilla: a review.

    PubMed

    Ali, Seyed Asharaf; Karthigeyan, Suma; Deivanai, Mangala; Kumar, Arun

    2014-09-01

    A severely atrophied maxilla presents serious limitations for conventional implant placement. This presents challenge to the surgeon for implant placement in harmony with the planned prosthesis. Survey of various literatures using internet sources, manual searches, and common textbooks on dental implants shows, that a thorough knowledge of conventional augmentation procedures such as bone augmentation techniques, guided bone regeneration, alveolar distraction, maxillary sinus elevation techniques with or without grafting and contemporary techniques of implant placement provide effective long-term solutions in the management of the atrophic maxilla. PMID:25183902

  11. Techniques for dental implant nanosurface modifications

    PubMed Central

    Bathala, Lakshmana Rao; Sangur, Rajashekar

    2014-01-01

    PURPOSE Dental implant has gained clinical success over last decade with the major drawback related to osseointegration as properties of metal (Titanium) are different from human bone. Currently implant procedures include endosseous type of dental implants with nanoscale surface characteristics. The objective of this review article is to summarize the role of nanotopography on titanium dental implant surfaces in order to improve osseointegration and various techniques that can generate nanoscale topographic features to titanium implants. MATERIALS AND METHODS A systematic electronic search of English language peer reviewed dental literature was performed for articles published between December 1987 to January 2012. Search was conducted in Medline, PubMed and Google scholar supplemented by hand searching of selected journals. 101 articles were assigned to full text analysis. Articles were selected according to inclusion and exclusion criterion. All articles were screened according to inclusion standard. 39 articles were included in the analysis. RESULTS Out of 39 studies, seven studies demonstrated that bone implant contact increases with increase in surface roughness. Five studies showed comparative evaluation of techniques producing microtopography and nanotopography. Eight studies concluded that osteoblasts preferably adhere to nano structure as compared to smooth surface. Six studies illustrated that nanotopography modify implant surface and their properties. Thirteen studies described techniques to produce nano roughness. CONCLUSION Modification of dental osseous implants at nanoscale level produced by various techniques can alter biological responses that may improve osseointegration and dental implant procedures. PMID:25558347

  12. Implant maintenance using a modified ultrasonic instrument.

    PubMed

    Kwan, J Y; Zablotsky, M H; Meffert, R M

    1990-01-01

    With the increasing number of implants in place, oral hygiene and maintenance are imperative because implants are susceptible to plaque accumulation and calculus formation. This case study evaluated a modification of the common ultrasonic tip to remove calcified deposits on implant abutments and prostheses, and also evaluated ultrastructural changes on polished titanium. A modified "plastic" ultrasonic instrument was found to be clinically effective and efficient. This instrument, unlike a metal ultrasonic tip on an ultrastructural level, produced no irreversible changes on the evaluated commercially pure titanium test strip. The preliminary results of this modification of an ultrasonic instrument show promise for its use as an implant maintenance modality. PMID:2098488

  13. Thoracic outlet syndrome following breast implant rupture.

    PubMed

    Mistry, Raakhi; Caplash, Yugesh; Giri, Pratyush; Kearney, Daniel; Wagstaff, Marcus

    2015-03-01

    We present a patient with bilateral breast implant rupture who developed severe locoregional silicone granulomatous lymphadenopathy. Poly Implant Prothese silicone implants had been used for bilateral breast augmentation 5 years prior. Extracapsular implant rupture and bilateral axillary lymphadenopathy indicated explantation, capsulectomy, and selective lymph node excision. Histology demonstrated silicone lymphadenopathy with no evidence of malignancy. Over the subsequent 12 months, she developed progressive locoregional lymphadenopathy involving bilateral cervical, axillary, and internal mammary groups, resulting in bilateral thoracic outlet syndrome. We report the unusual presentation, progression, and the ultimate surgical management of this patient. PMID:25878942

  14. Scleral melt following Retisert intravitreal fluocinolone implant

    PubMed Central

    Georgalas, Ilias; Koutsandrea, Chrysanthi; Papaconstantinou, Dimitrios; Mpouritis, Dimitrios; Petrou, Petros

    2014-01-01

    Intravitreal fluocinolone acetonide implant (Retisert) has a high potency, a low solubility, and a very short duration of action in the systemic circulation, enabling the steroid pellet to be small and reducing the risk of systemic side effects. Scleral melt has not been reported as a possible complication of Retisert implant. The authors describe the occurrence of scleral melt 18 months after the implantation of fluocinolone acetonide implant in a 42-year-old Caucasian woman. To the authors’ knowledge, this is the first report of this possible complication. PMID:25489235

  15. Diverse Roles of Prostaglandins in Blastocyst Implantation

    PubMed Central

    2014-01-01

    Prostaglandins (PGs), derivatives of arachidonic acid, play an indispensable role in embryo implantation. PGs have been reported to participate in the increase in vascular permeability, stromal decidualization, blastocyst growth and development, leukocyte recruitment, embryo transport, trophoblast invasion, and extracellular matrix remodeling during implantation. Deranged PGs syntheses and actions will result in implantation failure. This review summarizes up-to-date literatures on the role of PGs in blastocyst implantation which could provide a broad perspective to guide further research in this field. PMID:24616654

  16. Periodontio-integrated implants: A revolutionary concept.

    PubMed

    Gulati, Minkle; Anand, Vishal; Govila, Vivek; Jain, Nikil; Rastogi, Pavitra; Bahuguna, Rohit; Anand, Bhargavi

    2014-03-01

    Though the fields of regenerative dentistry and tissue engineering have undergone significant advancements, yet its application to the field of implant-dentistry is lacking; in the sense that presently the implants are being placed with the aim of attaining osseointegration without giving consideration to the regeneration of periodontium around the implant. The following article reveals the clinical benefits of such periodontio-integrated implants and reviews the relevant scientific proofs. A comprehensive research to provide scientific evidence supporting the feasibility of periodontio-integrated implants was carried out using various online resources such as PubMed, Wiley-Blackwell, Elsevier etc., to retrieve studies published between 1980 and 2012 using the following key words: "implant," "tissue engineering," "periodontium," "osseo-integration," "osseoperception," "regeneration" (and their synonyms) and it was found that in the past three decades, several successful experiments have been conducted to devise "implant supported by the periodontium"that can maintain form, function and potential proprioceptive responses similar to a natural tooth. Based on these staunch evidences, the possibility of the future clinical use of such implant can be strongly stated which would revolutionize the implant dentistry and will be favored by the patients as well. However, further studies are required to validate the same. PMID:24932184

  17. Air dissipation in saline breast implants.

    PubMed

    Schanzer, Andres; Wong, Granger B

    2002-06-01

    Residual air within saline breast implants can cause patient discomfort due to the mechanical and auditory effects of sloshing. Small amounts of air have no clinical significance, but if larger quantities are present and audible, the patient is reassured that the implant shell is gas-permeable and that the air will dissipate/diffuse. This study examined the time necessary for air dissipation in saline breast implants.Twelve McGhan style #68 saline breast implants were divided into two groups: group A, which included six implants with a size of 240 cc, and group B, which included six implants with a size of 270 cc. The implants were filled with room-temperature, intravenous, normal saline to their designated volumes, plus 30 cc of overfill. All air was evacuated, and each implant was inoculated with 5 cc of air. The implants were then submerged in a single tank of normal saline at 37 degrees C, at a depth of 20.4 cm to replicate capillary pressure. Intragroup analysis showed the air bubble was absent in group A at an average of 35.3 days (variance = 4.13) and in group B at an average of 38.0 days (variance = 0). If audible intraluminal air is present in the clinical setting, the patient can be reassured that the problem will resolve in approximately 30 days or less. PMID:12045543

  18. Thoracic Outlet Syndrome Following Breast Implant Rupture

    PubMed Central

    Caplash, Yugesh; Giri, Pratyush; Kearney, Daniel; Wagstaff, Marcus

    2015-01-01

    Summary: We present a patient with bilateral breast implant rupture who developed severe locoregional silicone granulomatous lymphadenopathy. Poly Implant Prothese silicone implants had been used for bilateral breast augmentation 5 years prior. Extracapsular implant rupture and bilateral axillary lymphadenopathy indicated explantation, capsulectomy, and selective lymph node excision. Histology demonstrated silicone lymphadenopathy with no evidence of malignancy. Over the subsequent 12 months, she developed progressive locoregional lymphadenopathy involving bilateral cervical, axillary, and internal mammary groups, resulting in bilateral thoracic outlet syndrome. We report the unusual presentation, progression, and the ultimate surgical management of this patient. PMID:25878942

  19. Ultrastructural characterization of the implant\\/bone interface of immediately loaded dental implants

    Microsoft Academic Search

    U. Meyer; U. Joos; J. Mythili; T. Stamm; A. Hohoff; T. Fillies; U. Stratmann; H. P. Wiesmann

    2004-01-01

    Primary stability and an optimized load transfer are assumed to account for an undisturbed osseointegration process of implants. Immediate loaded newly designed titanium dental implants inserted in the mandible of minipigs were used for the characterization of the interfacial area between the implant surface and the surrounding bone tissue during the early healing phase. Histological and electron microscopical studies were

  20. Bone response to radio frequency sputtered calcium phosphate implants and titanium implants in vivo.

    PubMed

    Ong, J L; Bessho, K; Cavin, R; Carnes, D L

    2002-01-01

    The objective of this study was to evaluate the effect of radio frequency sputtered calcium phosphate (CaP) coatings of titanium (Ti) implants on the bond strength at the bone-implant interface and percent bone contact length. Cylindrical coated or noncoated implants (4.0-mm diameter by 8-mm long) were implanted for 3 and 12 weeks. At 3 weeks after implant placement, the ultimate interfacial strengths for as-deposited CaP-coated and heat-treated CaP-coated implants were 2.29 +/- 0.14 MPa and 1.28 +/- 0.04 MPa, respectively. These ultimate interfacial strength values at 3 weeks were statistically greater than the mean ultimate interfacial strength for control Ti implants (0.67 +/- 0.13 MPa). At 12 weeks after implant placement, no statistical differences in the mean ultimate interfacial strengths were observed between the as-deposited CaP-coated, heat-treated CaP-coated, and control Ti implants. Histomorphometric evaluation indicated greater percent bone contact lengths for the as-deposited CaP-coated implants compared with the heat-treated CaP-coated and control Ti implants 3 and 12 weeks after implant placement. PMID:11745552

  1. Cost utility of the multichannel cochlear implants in 258 profoundly deaf individuals.

    PubMed

    Wyatt, J R; Niparko, J K; Rothman, M; deLissovoy, G

    1996-07-01

    Cost utility analysis is a method of cost-effectiveness analysis which provides results in terms of cost per quality-adjusted life-year (QALY). Cost utility for the multichannel cochlear implant was calculated using Ontario Health Utilities Index data from 229 Nucleus 22-channel implant users and 32 cochlear implant candidates awaiting surgery. The health utility of the implanted group was greater than that of the candidate group by 0.204 (P<.0001). Use of this figure in a cost utility calculation indicates that cochlear implantation costs approximately $15,928 per QALY provided. Sensitivity analysis, a technique which systematically varies the assumptions underlying the calculations, suggests a range for the true value of between $12,000 and $30,000. This compares very favorably with other medical interventions. It is concluded that profound hearing loss has a significant effect on quality of life, and measurement of the changes that result from cochlear implant use indicates that this technology provides significant improvements and is quite cost-effective. PMID:8667975

  2. Electrochemical Behaviours of Mg-4Zn-3Sn Cast Alloy Modified by Ti Ion Implantation

    NASA Astrophysics Data System (ADS)

    Zhu, Tianping; Fang, Fang; Kennedy, John; Gao, Wei

    Mg possesses good combinations of mechanical strength and ductility, which has become a good candidate for biodegradable material. However, its low corrosion resistance is an intriguing property for bio-application. Results show that some metals such as Sn, Zn and Ti are bio-compatible and can be tolerated in the human body. In this study, Ti+ ions were implanted into the subsurface of Mg-Sn-Zn alloys by ion implantation technology. The concentrations of Ti+ ions were selected as 2 % and 5 %, respectively. The morphologies of as-implanted surface were characterized by scanning electron microscopy (SEM) equipped with energy dispersive X-ray spectroscopy (EDX). Dynamic polarization analysis together with immersion tests in simulated body fluid were performed to study the anticorrosion properties of implanted alloys. The results show that Ti atoms can be successfully implanted into Mg alloy to pre-selected concentration and depth casing the increase of the corrosion potential. Specific results are discussed highlighting the opportunity of changing corrosion properties of Mg alloy by ion implantation.

  3. A Simple Novel Wireless Integrated Power Management Unit (PMU) for Rechargeable Battery-Operated Implantable Biomedical Telemetry Systems

    Microsoft Academic Search

    Peng Wang; Bo Liang; Xuesong Ye; Wen H. Ko; Peng Cong

    2010-01-01

    This paper presents a novel wireless integrated power management unit (PMU) for implantable biomedical telemetry systems. The PMU was fabricated in a 0.35?m CMOS technology occupying approximately 1×1 mm2. First, the presented unit can recharge implanted batteries via radio frequency power transmitted from an RF source. The charging voltage can be set in the range of 4.28V~5.3V for various batteries.

  4. 21 CFR 886.3300 - Absorbable implant (scleral buckling method).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...2010-04-01 2010-04-01 false Absorbable implant (scleral buckling method...Prosthetic Devices § 886.3300 Absorbable implant (scleral buckling method). (a) Identification. An absorbable implant (scleral buckling...

  5. Localization of cochlear implant electrodes in radiographs Siying Yang

    E-print Network

    Virginia Tech

    Localization of cochlear implant electrodes in radiographs Siying Yang Department of Electrical January 2000 Multielectrode cochlear implantation is the most effective treatment for profound sensorineural hearing loss. In vivo three-dimensional 3-D localization of cochlear implant electrodes

  6. Risk of Bacterial Meningitis in Children with Cochlear Implants

    MedlinePLUS

    ... Makers Risk of Bacterial Meningitis in Children with Cochlear Implants Language: English Español (Spanish) Recommend on Facebook Tweet ... the Risk of Bacterial Meningitis in Children with Cochlear Implants Many people have received cochlear implants to help ...

  7. Bilateral cochlear implants in children R. Litovskya,*, P. Johnstonea

    E-print Network

    Litovsky, Ruth

    Bilateral cochlear implants in children R. Litovskya,*, P. Johnstonea , A. Parkinsonb , R. Petersc of listening with bilateral cochlear implants (CIs) improves the ability of children to hear speech in noise reserved. Keywords: Bilateral; Cochlear; Implantation; Pediatric; Binaural; Experience 1. Introduction

  8. Simultaneous Bilateral Cochlear Implantation in Adults: A Multicenter Clinical Study

    E-print Network

    Litovsky, Ruth

    Simultaneous Bilateral Cochlear Implantation in Adults: A Multicenter Clinical Study Ruth Litovsky- neous" bilateral cochlear implantation (both im- plants placed during a single surgical procedure sensori- neural hearing loss. Performance with the bilateral cochlear implants, using the same speech

  9. A MANUAL INSERTION MECHANISM FOR PERCUTANEOUS COCHLEAR IMPLANTATION

    E-print Network

    Webster III, Robert James

    A MANUAL INSERTION MECHANISM FOR PERCUTANEOUS COCHLEAR IMPLANTATION Daniel Schurzig Vanderbilt. Webster III Vanderbilt University Nashville, TN, USA ABSTRACT Percutaneous Cochlear Implantation (PCI point. This precludes standard cochlear implant deployment techniques, and necessitates a new insertion

  10. 21 CFR 872.3970 - Interarticular disc prosthesis (interpositional implant).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...prosthesis (interpositional implant). 872.3970 Section...CONTINUED) MEDICAL DEVICES DENTAL DEVICES Prosthetic Devices...prosthesis (interpositional implant). (a) Identification...prosthesis (interpositional implant) is a device that is...

  11. 21 CFR 872.3970 - Interarticular disc prosthesis (interpositional implant).

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...prosthesis (interpositional implant). 872.3970 Section...CONTINUED) MEDICAL DEVICES DENTAL DEVICES Prosthetic Devices...prosthesis (interpositional implant). (a) Identification...prosthesis (interpositional implant) is a device that is...

  12. 21 CFR 872.3970 - Interarticular disc prosthesis (interpositional implant).

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...prosthesis (interpositional implant). 872.3970 Section...CONTINUED) MEDICAL DEVICES DENTAL DEVICES Prosthetic Devices...prosthesis (interpositional implant). (a) Identification...prosthesis (interpositional implant) is a device that is...

  13. 21 CFR 872.3970 - Interarticular disc prosthesis (interpositional implant).

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...prosthesis (interpositional implant). 872.3970 Section...CONTINUED) MEDICAL DEVICES DENTAL DEVICES Prosthetic Devices...prosthesis (interpositional implant). (a) Identification...prosthesis (interpositional implant) is a device that is...

  14. 21 CFR 872.3970 - Interarticular disc prosthesis (interpositional implant).

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...prosthesis (interpositional implant). 872.3970 Section...CONTINUED) MEDICAL DEVICES DENTAL DEVICES Prosthetic Devices...prosthesis (interpositional implant). (a) Identification...prosthesis (interpositional implant) is a device that is...

  15. Particle migration and gap healing around trabecular metal implants

    PubMed Central

    Kold, S.; Zippor, B.; Overgaard, S.; Søballe, K.

    2005-01-01

    Bone on-growth and peri-implant migration of polyethylene particles were studied in an experimental setting using trabecular metal and solid metal implants. Cylindrical implants of trabecular tantalum metal and solid titanium alloy implants with a glass bead blasted surface were inserted either in an exact surgical fit or with a peri-implant gap into a canine knee joint. We used a randomised paired design. Polyethylene particles were injected into the knee joint. In both types of surgical fit we found that the trabecular metal implants had superior bone ongrowth in comparison with solid metal implants (exact fit: 23% vs. 7% [p=0.02], peri-implant gap: 13% vs. 0% [p=0.02]. The number of peri-implant polyethylene particles was significantly reduced around the trabecular metal implants with a peri-implant gap compared with solid implants. PMID:16132987

  16. Sequential Bimodal Bilingual Acquisition: Mediation Using a Cochlear Implant as a Tool

    ERIC Educational Resources Information Center

    Cramér-Wolrath, Emelie

    2013-01-01

    Most deaf children are born to hearing families. During the last twenty years deaf children, in increasing numbers and at an early age, receive a cochlear implant, a highly technological hearing device. The aim of this qualitative, longitudinal, single-case study was to explore and describe critical changes in naturalistic, video-observed…

  17. Plasma Immersion Ion Implantation applied to P+N junction solar cells

    Microsoft Academic Search

    Vanessa Vervisch; D. Barakel; F. Torregrosa; L. Ottaviani; M. Pasquinelli

    2006-01-01

    Plasma immersion ion implantation is an alternative doping technique for the formation of Ultra Shallow Junctions in semiconductor. In this study, we present the PIII technology developed by the company Ion Beam Services and called PULSION®. We explain the advantages of PIII for the conception of thin emitter solar cells and the use of N type silicon in the fabrication

  18. Complete mouth implant rehabilitation with a zirconia ceramic system: a clinical report.

    PubMed

    Mehra, Mamta; Vahidi, Farhad

    2014-07-01

    Currently available ceramic systems offer a wide array of prosthetic advantages, including superior esthetics and enhanced physical and mechanical properties. The dental ceramic with the highest reported mechanical properties is zirconia. This clinical report describes a complete mouth implant rehabilitation with computer-aided design/computer-aided manufacturing technology and monolithic zirconia. PMID:24674807

  19. Bronchoscopic Implantation of a Novel Wireless Electromagnetic Transponder in the Canine Lung: A Feasibility Study

    SciTech Connect

    Mayse, Martin L. [Division of Pulmonary and Critical Care, Washington University School of Medicine, St. Louis, MO (United States); Parikh, Parag J. [Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO (United States)], E-mail: pparikh@radonc.wustl.edu; Lechleiter, Kristen M. [Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO (United States); Dimmer, Steven; Park, Mia [Calypso Medical Technologies, Seattle, WA (United States); Chaudhari, Amir [Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO (United States); Talcott, Michael [Division of Comparative Medicine, Washington University School of Medicine, St. Louis, MO (United States); Low, Daniel A.; Bradley, Jeffrey D. [Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO (United States)

    2008-09-01

    Purpose: The success of targeted radiation therapy for lung cancer treatment is limited by tumor motion during breathing. A real-time, objective, nonionizing, electromagnetic localization system using implanted electromagnetic transponders has been developed (Beacon electromagnetic transponder, Calypso Medical Technologies, Inc., Seattle, WA). We evaluated the feasibility and fixation of electromagnetic transponders bronchoscopically implanted in small airways of canine lungs and compared to results using gold markers. Methods and Materials: After approval of the Animal Studies Committee, five mongrel dogs were anesthetized, intubated, and ventilated. Three transponders were inserted into the tip of a plastic catheter, passed through the working channel of a flexible bronchoscope, and implanted into small airways of a single lobe using fluoroscopic guidance. This procedure was repeated for three spherical gold markers in the opposite lung. One, 7, 14, 28, and 60 days postimplantation imaging was used to assess implant fixation. Results: Successful bronchoscopic implantation was possible for 15 of 15 transponders and 12 of 15 gold markers; 3 markers were deposited in the pleural space. Fixation at 1 day was 15 of 15 for transponders and 12 of 12 for gold markers. Fixation at 60 days was 6 of 15 for transponders and 7 of 12 for gold markers, p value = 0.45. Conclusions: Bronchoscopic implantation of both transponders and gold markers into the canine lung is feasible, but fixation rates are low. If fixation rates can be improved, implantable electromagnetic transponders may allow improved radiation therapy for lung cancer by providing real-time continuous target tracking. Developmental work is under way to improve the fixation rates and to reduce sensitivity to implantation technique.

  20. Bilingualism: A Pearl to Overcome Certain Perils of Cochlear Implants

    PubMed Central

    Humphries, Tom; Kushalnagar, Poorna; Mathur, Gaurav; Napoli, Donna Jo; Padden, Carol; Rathmann, Christian; Smith, Scott

    2014-01-01

    Cochlear implants (CI) have demonstrated success in improving young deaf children’s speech and low-level speech awareness across a range of auditory functions, but this success is highly variable, and how this success correlates to high-level language development is even more variable. Prevalence on the success rate of CI as an outcome for language development is difficult to obtain because studies vary widely in methodology and variables of interest, and because not all cochlear implant technology (which continues to evolve) is the same. Still, even if the notion of treatment failure is limited narrowly to those who gain no auditory benefit from CI in that they cannot discriminate among ambient noises, the reported treatment failure rate is high enough to call into question the current lack of consideration of alternative approaches to ensure young deaf children’s language development. Recent research has highlighted the risks of delaying language input during critical periods of brain development with concomitant consequences for cognitive and social skills. As a result, we propose that before, during, and after implantation deaf children learn a sign language along with a spoken language to ensure their maximal language development and optimal long-term developmental outcomes. PMID:25419095