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1

Ten-year follow-up of survival and myocardial infarction in the randomized Coronary Artery Surgery Study.  

PubMed

The Coronary Artery Surgery Study (CASS) randomized 780 patients to an initial strategy of coronary surgery or medical therapy. Of medically randomized patients, 6% had surgery within 6 months and a total of 40% had surgery by 10 years. At 10 years, there was no difference in cumulative survival (medical, 79% vs. surgical, 82%; NS) and no difference in percentage free of death and nonfatal myocardial infarction (medical, 69% vs. surgical, 66%; NS). Patients with an ejection fraction of less than 0.50 exhibited a better survival with initial surgery treatment (medical, 61% vs. surgical, 79%; p = 0.01). Conversely, patients with an ejection fraction greater than or equal to 0.50 exhibited a higher proportion free of death and myocardial infarction with initial medical therapy (medical, 75% vs. surgical, 68%; p = 0.04) although long-term survival remained unaffected (medical, 84% vs. surgical, 83%; p = 0.75). There were no significant differences either in survival and freedom from nonfatal myocardial infarction, whether stratified on presence of heart failure, age, hypertension, or number of vessels diseased. Thus, 10-year follow-up results confirm earlier reports from CASS that patients with left ventricular dysfunction exhibit long-term benefit from an initial strategy of surgical treatment. Patients with mild stable angina and normal left ventricular function randomized to initial medical treatment (with an option for later surgery if symptoms progress) have survival equivalent to those patients randomized to initial surgery. PMID:2225367

Alderman, E L; Bourassa, M G; Cohen, L S; Davis, K B; Kaiser, G G; Killip, T; Mock, M B; Pettinger, M; Robertson, T L

1990-11-01

2

Positive effect of removal of subchondral bone plate for cemented acetabular component fixation in total hip arthroplasty: a randomised RSA study with ten-year follow-up.  

PubMed

We hypothesised that the removal of the subchondral bone plate (SCBP) for cemented acetabular component fixation in total hip arthroplasty (THA) offers advantages over retention by improving the cement-bone interface, without jeopardising implant stability. We have previously published two-year follow-up data of a randomised controlled trial (RCT), in which 50 patients with primary osteoarthritis were randomised to either retention or removal of the SCBP. The mean age of the retention group (n = 25, 13 males) was 70.0 years (sd 6.8). The mean age in the removal group (n = 25, 16 males) was 70.3 years (sd 7.9). Now we have followed up the patients at six (retention group, n = 21; removal group, n = 20) and ten years (retention group: n = 17, removal group: n = 18), administering clinical outcome questionnaires and radiostereometric analysis (RSA), and determining the presence of radiolucent lines (RLLs) on conventional radiographs. RSA demonstrated similar translation and rotation patterns up to six years. Between six and ten years, proximal acetabular component migration and changes of inclination were larger in the retention group, although the mean differences did not reach statistical significance. Differences in migration were driven by two patients in the SCBP retention group with extensive migration versus none in the SCBP removal group. The significant difference (p < 0.001) in the development of radiolucent lines in the retention group, previously observed at two years, increased even further during the course of follow-up (p < 0.001). While recognising SCBP removal is a more demanding technique, we conclude that, wherever possible, the SCBP should be removed to improve the cement-bone interface in order to maximise acetabular component stability and longevity. PMID:25568411

Flivik, G; Kristiansson, I; Ryd, L

2015-01-01

3

Clinical and radiographic outcomes of acetabular impaction grafting without cage reinforcement for revision hip replacement: a minimum ten-year follow-up study.  

PubMed

Impaction bone grafting for the reconstitution of bone stock in revision hip surgery has been used for nearly 30 years. Between 1995 and 2001 we used this technique in acetabular reconstruction, in combination with a cemented component, in 304 hips in 292 patients revised for aseptic loosening. The only additional supports used were stainless steel meshes placed against the medial wall or laterally around the acetabular rim to contain the graft. All Paprosky grades of defect were included. Clinical and radiographic outcomes were collected in surviving patients at a minimum of ten years after the index operation. Mean follow-up was 12.4 years (sd 1.5) (10.0 to 16.0). Kaplan-Meier survival with revision for aseptic loosening as the endpoint was 85.9% (95% CI 81.0 to 90.8) at 13.5 years. Clinical scores for pain relief remained satisfactory, and there was no difference in clinical scores between cups that appeared stable and those that appeared radiologically loose. PMID:24493183

Gilbody, J; Taylor, C; Bartlett, G E; Whitehouse, S L; Hubble, M J W; Timperley, A J; Howell, J R; Wilson, M J

2014-02-01

4

Auditory and Visual Health after Ten Years of Exposure to Metal-on-Metal Hip Prostheses: A Cross-Sectional Study Follow Up  

PubMed Central

Case reports of patients with mal-functioning metal-on-metal hip replacement (MoMHR) prostheses suggest an association of elevated circulating metal levels with visual and auditory dysfunction. However, it is unknown if this is a cumulative exposure effect and the impact of prolonged low level exposure, relevant to the majority of patients with a well-functioning prosthesis, has not been studied. Twenty four male patients with a well-functioning MoMHR and an age and time since surgery matched group of 24 male patients with conventional total hip arthroplasty (THA) underwent clinical and electrophysiological assessment of their visual and auditory health at a mean of ten years after surgery. Median circulating cobalt and chromium concentrations were higher in patients after MoMHR versus those with THA (P<0.0001), but were within the Medicines and Healthcare Products Regulatory Agency (UK) investigation threshold. Subjective auditory tests including pure tone audiometric and speech discrimination findings were similar between groups (P>0.05). Objective assessments, including amplitude and signal-to-noise ratio of transient evoked and distortion product oto-acoustic emissions (TEOAE and DPOAE, respectively), were similar for all the frequencies tested (P>0.05). Auditory brainstem responses (ABR) and cortical evoked response audiometry (ACR) were also similar between groups (P>0.05). Ophthalmological evaluations, including self-reported visual function by visual functioning questionnaire, as well as binocular low contrast visual acuity and colour vision were similar between groups (P>0.05). Retinal nerve fibre layer thickness and macular volume measured by optical coherence tomography were also similar between groups (P>0.05). In the presence of moderately elevated metal levels associated with well-functioning implants, MoMHR exposure does not associate with clinically demonstrable visual or auditory dysfunction. PMID:24621561

Prentice, Jennifer R.; Blackwell, Christopher S.; Raoof, Naz; Bacon, Paul; Ray, Jaydip; Hickman, Simon J.; Wilkinson, J. Mark

2014-01-01

5

Indirect composite restorations luted with two different procedures: A ten years follow up clinical trial  

PubMed Central

Objectives: The aim of this clinical trial was to evaluate posterior indirect composite resin restoration ten years after placement luted with two different procedures. Study Design: In 23 patients 22 inlays/onlays (Group A) were luted using a dual-cured resin composite cement and 26 inlays/onlays (Group B) were luted using a light cured resin composite for a total of 48 Class I and Class II indirect composite resin inlays and onlays. The restorations were evaluated at 2 time points: 1) one week after placement (baseline evaluation) and 2) ten years after placement using the modified USPHS criteria. The Mann-Whitney and the Wilcoxon tests were used to examine the difference between the results of the baseline and 10 years evaluation for each criteria. Results: Numerical but not statistically significant differences were noted on any of the recorded clinical parameters (p>0.05) between the inlay/onlays of Group A and Group B. 91% and 94 % of Group A and B respectively were rated as clinically acceptable in all the evaluated criteria ten years after clinical function. Conclusions: Within the limits of the study the results showed after ten years of function a comparable clinical performance of indirect composite resin inlays/onlays placed with a light cure or dual cure luting procedures. Key words:Light curing composite, dual curing composite, indirect composite restoration, inlays/onlays, clinical trial.

Preti, Alessandro; Vano, Michele; Derchi, Giacomo; Mangani, Francesco; Cerutti, Antonio

2015-01-01

6

Five and Ten Year Follow-up on Intradiscal Ozone Injection for Disc Herniation  

PubMed Central

Background Disc herniation is the most common cause for spinal surgery and many clinicians employ epidural steroid injections with limited success. Intradiscal injection of ozone gas has been used as an alternative to epidural steroids and surgical discectomy. Early results are positive but long-term data are limited. Methods One hundred and eight patients with confirmed contiguous disc herniation were treated with intradiscal injection of ozone in 2002-2003. One-hundred seven patients were available for telephone follow-up at 5 years. Sixty patients were available for a similar telephone follow-up at ten years. Patients were asked to describe their clinical outcome since the injection. Surgical events were documented. MRI images were reviewed to assess the reduction in disc herniation at six months. Results MRI films demonstrated a consistent reduction in the size of the disc herniation. Seventy-nine percent of patients had a reduction in herniation volume and the average reduction was 56%. There were 19 patients that ultimately had surgery and 12 of them occurred in the first six months after injection. One of these 12 was due to surgery at another level. Two surgeries involved an interspinous spacer indicated by stenosis or DDD. All other surgeries were discectomies. Of the patients that avoided surgery 82% were improved at 5 years and 88% were improved at 10 years. Other than subsequent surgeries, no spine-related complications were experienced. Conclusions/Level of Evidence We conclude that ozone is safe and effective in approximately 75% of patients with disc herniation and the benefit is maintained through ten years. This is a retrospective review and randomized trials are needed. Clinical Relevance Intradiscal ozone injection may enable patients to address their pain without multiple epidural injections and surgery. The benefit of ozone is durable and does not preclude future surgical options. The risk reward profile for this treatment is favorable. PMID:25694935

Buric, Josip; Rigobello, Luca; Hooper, David

2014-01-01

7

Ten year follow up of pulmonary function in patients with primary Sjögren's syndrome  

PubMed Central

OBJECTIVES—To follow up a previous report on the lung function of patients with primary Sjögren's syndrome (SS), and describe the findings having followed up this cohort for a median duration of 10 years (range 8-12 years).?METHODS—30 patients fulfilling Fox's criteria for definite or probable primary SS were assessed within six months of diagnosis and after a median duration of four and then 10 years by a clinical examination, chest radiograph, and lung function studies (FEV1, FVC, TLCO, and KCO).?RESULTS—At baseline, symptomatic dyspnoea was a common finding, reported by 13/30 patients, of whom two had evidence of fibrosing alveolitis on plain chest radiograph. Five patients had a carbon monoxide transfer factor (TLCO) more than two standardised residuals below the predicted value. After four years' follow up two further patients developed radiological fibrotic changes and there were significant reductions in TLCO (p<0.02) and transfer coefficient (KCO) (p<0.02) compared with the baseline measurements. At 10 years' follow up four patients had died and four were lost to follow up. One patient with fibrosing alveolitis had died from chest disease. There were no further cases of pulmonary fibrosis identified on plain chest radiograph. The lung function studies showed no further deterioration from the results found at year four with significant improvements in both TLCO (p<0.001) and KCO (p<0.001). Those patients who were anti-Ro antibody positive had significantly lower transfer factors than patients with primary SS without this serological marker (p<0.02).?CONCLUSION—This long term follow up of lung disease in primary SS is reassuring, and suggests that most patients do not develop progressive lung disease. Pulmonary disease occurs predominantly in anti-Ro antibody positive patients and presents early in the course of the disease.?? PMID:10976085

Davidson, B; Kelly, C; Griffiths, I

2000-01-01

8

Ten-Year Follow-Up of Endovascular Aneurysm Treatment with Talent Stent-Grafts  

SciTech Connect

The purpose of this study was to evaluate the clinical results, complications, and secondary interventions during long-term follow-up after endovascular aneurysm repair (EVAR) and to investigate the impact of endoleak sizes on aneurysm shrinkage. From 1997 to March 2007, 127 patients (12 female, 115 male; age, 73.0 {+-} 7.2 years) with abdominal aortic aneurysms were treated with Talent stent-grafts. Follow-up included clinical visits, contrast-enhanced MDCT, and radiographs at 3, 6, and 12 months and then annually. Results were analyzed with respect to clinical outcome, secondary interventions, endoleak rate and management, and change in aneurysm size. There was no need for primary conversion surgery. Thirty-day mortality was 1.6% (two myocardial infarctions). Procedure-related morbidity was 2.4% (paraplegia, partial infarction of one kidney, and inguinal bleeding requiring surgery). Mean follow-up was 47.7 {+-} 34.2 months (range, 0-123 months). Thirty-nine patients died during follow-up; three of the deaths were related to aneurysm (aneurysm rupture due to endoleak, n = 1; secondary surgical reintervention n = 2). During follow-up, a total of 29 secondary procedures were performed in 19 patients, including 14 percutaneous procedures (10 patients) and 15 surgical procedures (12 patients), including 4 cases with late conversion to open aortic repair (stent-graft infection, n = 1; migration, endoleak, or endotension, n = 3). Overall mean survival was 84.5 {+-} 4.7 months. Mean survival and freedom from any event was 66.7 {+-} 4.5 months. MRI depicted significantly more endoleaks compared to MDCT (23.5% vs. 14.3%; P < 0.01). Patients in whom all aneurysm side branches were occluded prior to stent-grafting showed a significantly reduced incidence of large endoleaks. Endoleaks >10% of the aneurysm area were associated with reduced aneurysm shrinkage compared to no endoleaks or <10% endoleaks ({Delta} at 3 years, -1.8% vs. -12.0%; P < 0.05). In conclusion, endovascular aneurysm treatment with Talent stent-grafts demonstrated encouraging long-term results with moderate secondary intervention rates. Primary occlusion of all aortic side branches reduced the incidence of large endoleaks. Large endoleaks significantly impaired aneurysm shrinkage, whereas small endoleaks did not.

Pitton, Michael B., E-mail: pitton@radiologie.klinik.uni-mainz.de; Scheschkowski, Tobias; Ring, Markus; Herber, Sascha; Oberholzer, Katja; Leicher-Dueber, Annegret [University Hospital of Mainz, Johannes Gutenberg University of Mainz, Department of Diagnostic and Interventional Radiology (Germany); Neufang, Achim; Schmiedt, Walther [University Hospital of Mainz, Johannes Gutenberg University of Mainz, Department of Cardiovascular and Thoracic Surgery (Germany); Dueber, Christoph [University Hospital of Mainz, Johannes Gutenberg University of Mainz, Department of Diagnostic and Interventional Radiology (Germany)

2009-09-15

9

Ten-Year Follow-Up of the First Megatrial Testing Thrombolytic Therapy in Patients With Acute Myocardial Infarction: Results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto-1 Study  

Microsoft Academic Search

Background—We conducted a 10-year follow-up of the 11 712 patients with acute myocardial infarction randomized in the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto-1 study, the first large trial assessing thrombolytic therapy. Methods and Results—Information on survival at 10 years was obtained for the 93% of all randomized patients through the census offices of their towns of residence. The

Maria Grazia; De Vita; Enrico Geraci; Antonio Lotto; Aldo P. Maggioni; Francesco Mauri; Fausto Rovelli; Gianni Tognoni; Maria Grazia Franzosi; Mario Negri

10

Ten-year follow-up of the non-porous Allofit cementless acetabular component.  

PubMed

Cementless acetabular fixation has demonstrated superior long-term durability in total hip replacement, but most series have studied implants with porous metal surfaces. We retrospectively evaluated the results of 100 consecutive patients undergoing total hip replacement where a non-porous Allofit component was used for primary press-fit fixation. This implant is titanium alloy, grit-blasted, with a macrostructure of forged teeth and has a biradial shape. A total of 81 patients (82 hips) were evaluated at final follow-up at a mean of 10.1 years (8.9 to 11.9). The Harris Hip Score improved from a mean 53 points (23 to 73) pre-operatively to a mean of 96 points (78 to 100) at final review. The osseointegration of all acetabular components was radiologically evaluated with no evidence of loosening. The survival rate with revision of the component as the endpoint was 97.5% (95% confidence interval 94 to 100) after 11.9 years. Radiolucency was found in one DeLee-Charnley zone in four acetabular components. None of the implants required revision for aseptic loosening. Two patients were treated for infection, one requiring a two-stage revision of the implant. One femoral stem was revised for osteolysis due to the production of metal wear debris, but the acetabular shell did not require revision. This study demonstrates that a non-porous titanium acetabular component with adjunct surface fixation offers an alternative to standard porous-coated implants. PMID:19880887

Zenz, P; Stiehl, J B; Knechtel, H; Titzer-Hochmaier, G; Schwagerl, W

2009-11-01

11

TEN-YEAR FOLLOW UP OF A PHASE II STUDY OF DOSE-INTENSE PACLITAXEL WITH CISPLATIN AND CYCLOPHOSPHAMIDE AS INITIAL THERAPY FOR POOR-PROGNOSIS ADVANCED-STAGE EPITHELIAL OVARIAN CANCER  

PubMed Central

SUMMARY Background To assess activity and toxicity in newly diagnosed advanced stage epithelial ovarian cancer (EOC) patients receiving dose-intense paclitaxel, cyclophosphamide, cisplatin, and filgrastim delivered with a flexible dosing schedule. Methods Patients with Stage III/IV EOC received cyclophosphamide 750 mg/m2, followed by 24 hr infusion of paclitaxel 250 mg/m2, and cisplatin 75 mg/m2 on day 2. Filgrastim began on day 3 at 10 ?g/kg/d × 9d. Patients received six cycles of all drugs. Those with pathologic complete response or microscopic residual disease at the conclusion of six cycles of therapy received an additional cycles two to four cycles of paclitaxel with cyclophosphamide. Patients with objective response continued cyclophosphamide and paclitaxel. Results 62 patients were enrolled. Thirty-two of these 62 patients had stage IIIC disease, and 26 of 62 had stage IV disease. Using an intent to treat analysis, 55 (89%) experienced clinical complete remission (CCR). With a median potential follow-up of 11.4 years, the median progression free survival is 18.9 months and median survival is 5.4 years. The most serious toxicity was grade 3/4 neutropenic fever (35%). Although all participants developed peripheral neuropathy, improvement in neuropathic symptoms began with decrease or cessation of paclitaxel. Conclusions This regimen yielded a high response rate and encouraging overall survival. These data and those of the Japanese Gynecologic Oncology Group suggest that further study of dose dense or intense paclitaxel regimens in women with newly diagnosed advanced stage EOC is warranted. PMID:20091841

Sarosy, Gisele A.; Hussain, Mahrukh M.; Seiden, Michael V.; Fuller, A.F.; Nikrui, N.; Goodman, Annekathryn; Minasian, Lori; Reed, Eddie; Steinberg, Seth M.; Kohn, Elise C.

2009-01-01

12

Gastrointestinal Involvement in Lipoid Proteinosis: A Ten-Year Follow-Up of a Brazilian Female Patient  

PubMed Central

Lipoid proteinosis is a rare autosomal recessive disease characterized by the deposition of hyaline material in the skin and internal organs. The main clinical features are hoarseness and typical skin lesions. In this report we describe the endoscopic and radiologic findings in a Brazilian female patient presenting extensive gastrointestinal involvement and the evolution of the detected lesions in ten years of follow-up. Initial upper endoscopy and colonoscopy showed a similar pattern of multiple yellowish nodules throughout the esophagus, stomach, duodenum, and colons. Histological analysis confirmed the diagnosis of lipoid proteinosis. In addition, small bowel follow through demonstrated numerous well defined, round, small filling defects throughout the jejunum. Ten years later, the esophageal lesions remained the same, but none of the previous alterations were detected in the stomach, duodenum, and colons. In conclusion, lipoid proteinosis may affect all gastrointestinal organs with the same pattern of macroscopic and microscopic lesions. Some lesions may regress with increasing age. PMID:25045357

Custódio Lima, Juliana; Nagasako, Cristiane Kibune; Montes, Ciro Garcia; Barcelos, Irene Harumi Kamata; de Carvalho, Rita Barbosa

2014-01-01

13

Minimum ten-year follow-up of cemented total hip replacement in patients with osteonecrosis of the femoral head.  

PubMed

Between November 1970 and September 1984 the senior author performed fifty-three consecutive total hip arthroplasties with cement in forty-one patients with the diagnosis of osteonecrosis of the femoral head. Five hips in three patients with failed renal transplants requiring chronic hemodialysis were excluded. At the time of final review, a minimum of ten years after the procedure, twenty-one patients (twenty-eight hips) were living, fifteen patients (eighteen hips) had died, and two patients (two hips) were lost to follow-up. A minimum ten-year follow-up radiograph was obtained on twenty-two (79%) of the hips in surviving patients. During the follow-up period 17.4% of hips (eight hips) required revision: 13.0% (six hips) for aseptic loosening, 2.2% (one hip) for sepsis, and 2.2% (one hip) for recurrent dislocation. All eight revisions occurred in patients living at time of final review, giving a revision prevalence of 22.9% (17.1% for aseptic loosening, 2.9% for sepsis, and 2.9% for recurrent dislocation) in patients surviving ten years. The prevalence of revision of the femoral component for aseptic loosening was 6.5% (three hips) for all hips and 9.1% (three hips) in patients surviving at least ten years. The prevalence of femoral aseptic loosening, defined as those components revised for aseptic loosening and those that demonstrated definite or probable radiographic loosening, was 13.0% (six hips) for all hips and 28.6% (six hips) for hips with at least ten-year radiographic follow-up. The prevalence of revision of the acetabular component for aseptic loosening was 13.0% (six hips) for all hips and 18.2% (six hips) in patients surviving at least ten years. The prevalence of acetabular aseptic loosening was 15.2% (seven hips) for all hips and 29.2% (seven hips) for hips with at least ten-year radiographic follow-up. In patients with osteonecrosis of the femoral head survivorship was significantly inferior to that in the senior author's overall patient population with regard to revision for aseptic loosening (p=0.019), revision for acetabular loosening (p=0.01), revision for femoral loosening (p=0.008), and aseptic femoral loosening (p=0.004). Survivorship to aseptic acetabular loosening was not significantly different (p=0.32). Young age at the time of surgery significantly increased the risk of subsequent component loosening (p<0.008) and revision due to aseptic loosening (p<0.002). These findings demonstrate the relatively poor durability of cemented total hip arthroplasty in patients with osteonecrosis of the femoral head as compared to patients with other diagnoses and suggest that the younger age in this patient population compromises results. PMID:12180617

Fyda, Thomas M; Callaghan, John J; Olejniczak, Jason; Johnston, Richard C

2002-01-01

14

Construction work and risk of occupational disability: a ten year follow up of 14 474 male workers  

PubMed Central

Aims: Most industrialised countries have public income maintenance programmes to protect workers in case of disability but studies addressing disability risk of specific professional groups are rare. The objective of this study was to establish a detailed pattern of the nature and extent of occupational disability among construction workers. Methods: A cohort study was set up including 14 474 male workers from the construction industry in Württemberg (Germany) aged 25–64 years who underwent occupational health exams between 1986 and 1992. The cohort was linked to the regional pension register of the manual workers' pension insurance institution to identify workers who were granted a disability pension during the 10 year follow up. All-cause and cause specific standardised incidence ratios (SIR) and 95% confidence intervals (CI) were calculated using disability rates from the general workforce and from all blue collar workers in Germany as references. Results: In total, 2247 (16%) members of the cohort were granted a disability pension. Major causes of disability were musculoskeletal (45%) and cardiovascular diseases (19%). In comparison with the general workforce, construction workers experienced a higher risk of disability from cancer (SIR = 1.26; 95% CI 1.08 to 1.47), respiratory diseases (SIR = 1.27; 95% CI 1.03 to 1.55), musculoskeletal diseases (SIR = 2.16; 95% CI 2.03 to 2.30), injuries/poisoning (SIR = 2.52; 95% CI 2.06 to 3.05), and all causes combined (SIR = 1.47; 95% CI 1.41 to 1.53). When compared with the blue collar reference group, increased risks of disability among construction workers were found for musculoskeletal diseases (SIR = 1.53; 95% CI 1.44 to 1.63), injury/poisoning (SIR = 1.83; 95% CI 1.50 to 2.21), and all causes combined (SIR = 1.11; 95% CI 1.07 to 1.16). Conclusions: Musculoskeletal diseases and external causes are major factors limiting the work capability of construction workers and lead to an increased proportion of occupational disability. PMID:16046609

Arndt, V; Rothenbacher, D; Daniel, U; Zschenderlein, B; Schuberth, S; Brenner, H

2005-01-01

15

The ten-year follow-up of the Bedford Survey (1962–1972): Glucose tolerance and diabetes  

Microsoft Academic Search

Summary  In a 10-year prospective study of 241 people with borderline diabetes (impaired glucose tolerance) identified by screening of the Bedford adult population, 36 (15%) worsened to diabetes and 128 (53%) substantially improved their glucose tolerance. The major predictor of worsening to diabetes was the level of blood glucose at baseline. This was statistically significant (p p

H. Keen; R. J. Jarrett; P. McCartney

1982-01-01

16

Total body irradiation for stage II-IV non-Hodgkin's lymphoma: ten-year follow-up  

SciTech Connect

Between 1972 and 1977, a prospective study was conducted at the University of Florida on the role of total body irradiation (TBI) in the management of stage II-IV non-Hodgkin's lymphoma (NHL). Forty-four consecutive de novo (DN) patients (including ten stage II, 18 stage III, and 16 stage IV), as well as 16 previously treated (PT) patients, were accrued. Twenty of the 44 DN patients were symptomatic at presentation. Complete clinical responses were obtained in 20 of the 27 DN patients with favorable histologies (FH), and six of the 17 with unfavorable histologies (UH). Partial responses were obtained in six patients with FH and 11 patients with UH; only one patient showed no response to TBI. By univariate analysis, PT patients showed a trend for decreased relapse-free survival (P = .066) and decreased survival (P = .093). Multivariate analysis identified the best predictors of response rate to be histology (P = .0146) and marrow involvement (P = .0854); of relapse-free survival, histology (P = .0035), and TBI dose (P = .002); and of absolute survival, age (P = .0012), histology (P = .012), and TBI dose (P = .029). Thirty of the 41 patients who relapsed underwent salvage treatment with either chemotherapy or radiation. Twenty-three of the 30 undergoing salvage therapy obtained a second complete clinical response. There were no treatment-related deaths. The most common complication was thrombocytopenia. The major late complications were myeloproliferative disorders in four patients, which occurred only after cumulative TBI doses in excess of 200 cGy.

Mendenhall, N.P.; Noyes, W.D.; Million, R.R.

1989-01-01

17

[Importance of thorough removal of all affected tissues before grafting epidermolysis bullosa lesions: ten-year follow-up of one patient with multiple grafts].  

PubMed

We present the case of a patient suffering from dominantly inherited dystrophic epidermolysis bullosa and followed over a period of ten years. Skin lesions of this patient have been treated with multiple thin skin grafts applied over Integra®. The experience proved that, in order to have a perfect graft take, it was necessary to remove all the affected tissues, which includes an abnormally thickened dermis, and also a portion of the subcutaneous tissue. PMID:21783305

Huguier, V; Messaoudi, R; Rousseau, P; Levillain, P; Dagregorio, G

2013-08-01

18

Ten-Year Follow-Up of 3 Years of Oral Adjuvant Clodronate Therapy Shows Significant Prevention of Osteoporosis in Early-Stage Breast Cancer  

Microsoft Academic Search

Purpose We have previously reported that 3-year adjuvant clodronate treatment prevents bone loss in breast cancer patients. Here we report the 10-year follow-up data of clodronate in the prevention of treatment-related osteoporosis in women with early-stage breast cancer. Patients and Methods Two hundred sixty-eight pre- and postmenopausal, node-positive breast cancer patients were randomly assigned to clodronate, 1.6 g orally administered

Tiina Saarto; Leena Vehmanen; Carl Blomqvist; Inkeri Elomaa

19

Ten years of Developing International Volcanology Graduate Study Programs  

NASA Astrophysics Data System (ADS)

In 2000 I reported at this symposium about multi-institutional graduate field trips to IAVCEI events, such as the Bali meeting and its importance in building international collegiality and awareness among the volcanology doctoral students. NSF was an enthusiastic supporter of these field sessions and this support has continued through the highly successful Pucon and Reykjavik sessions. International volcanology graduate program development began with several exchange programs. EHaz was a highly successful program (McGill, Simon Fraser, Michigan Tech, Buffalo, UNAM and Universidad de Colima) funded by the Department of Education (FIPSE) that moved students across North America where dozens of graduate students spent semesters of their study abroad and shared annual field trips and online student led graduate seminar classes. Michigan Tech’s volcanology graduate program started a Masters International program that combined Peace Corps service with hazards mitigation graduate study and students were placed by Peace Corps in countries with prominent natural hazards. The new program funded 2 year residences in foreign environments, principally in Pacific Latin America. NSF strongly supported this program from its inception, and eventually it gained NSF PIRE support. Dozens of students have initiated the 3 year program (15 completed) to date. A similar PIRE developed at UAF with a link to volcanology in the Russian Far East. One gain is the development of many socially-conscious research selections. Beginning this year transatlantic dual degree masters programs in volcanology are being offered by a consortium of US and European volcanology programs (Michigan Tech, Buffalo, Clermont Ferrand and University of Milan Bicocca), again aided by FIPSE funding. Students have dual advisors on both sides of the Atlantic and spend about half of their two year programs in Europe and half in US. Faculty also travel in the program and the four campuses are increasingly linked by coursework and research networks. Because the international developments of volcanology programs address the need for more robust coursework and research choices for students than are possible on one campus, and because they lead to a diverse network of professional contacts , we think the next decade will bring many more multi-university volcanology programs linked to field sites all over the world.

Rose, W. I.

2010-12-01

20

Ten-year follow-up of a prospective trial for the targeted therapy of gastric cancer with the human monoclonal antibody PAT-SC1.  

PubMed

The fully human monoclonal antibody PAT-SC1 is specific for an isoform of CD55 (decay-accelerating factor) designated CD55PAT-SC1. This antigen is expressed in the majority (80%) of gastric cancers (GCs), and the antibody induces tumour cell-specific apoptosis in vitro as well as in vivo. PAT-SC1, therefore, has been deemed promising as a therapeutic agent. Here, we describe the results of an academic clinical study performed in a neoadjuvant setting with resectable GC patients. Patients undergoing treatment for GC between 1997 and 2001 were tested for CD55PAT-SC1 expression. Fifty-one resectable patients that tested positively received a single administration of 20 mg PAT-SC1 48 h prior to surgery. They underwent standard surgery with either subtotal or total gastrectomy with bursectomy, omentectomy and a modified D2-lymphadenectomy, aimed at R0 resection. Primary endpoints of the present study were to evaluate side-effects of the PAT-SC1 antibody treatment and to evaluate histopathological effects such as tumour regression and induction of apoptosis. Long-term survival was a secondary endpoint. Administration of PAT-SC1 appeared safe with only reversible side-effects according to WHO grade I and II. Despite the low?dose of the antibody, 81.6% of the patients showed signs of increased apoptosis within the primary tumour and 60% showed signs of tumour cell regression. Comparison of the 10-year survival rates of the R0-resected CD55PAT-SC1-positive patients treated with the PAT-SC1 antibody with a historical collective of R0-resected CD55PAT-SC1-positive patients not treated with PAT-SC1 indicated a survival benefit in the treated patients. Furthermore, comparison of the patient survival of CD55PAT?SC1-positive vs. CD55PAT-SC1-negative groups suggested that CD55PAT-SC1 antigen expression is an independent predictor of poor survival in a Cox regression analysis. Antibody PAT-SC1 may be a useful additive therapeutic agent in the treatment of patients with CD55PAT-SC1-expressing GCs. In combination with radical standard surgery, PAT-SC1 given as an adjuvant or neoadjuvant immunotherapeutic agent induces apoptosis in tumour cells which may improve survival of these patients. Because of the human origin and its specific binding to the CD55PAT-SC1 antigen, PAT-SC1 was well tolerated in this trial. PMID:24452482

Hensel, Frank; Timmermann, Wolfgang; von Rahden, Burkhard H A; Rosenwald, Andreas; Brändlein, Stephanie; Illert, Bertram

2014-03-01

21

Follow-up study of alcoholic hallucinosis  

PubMed Central

Alcoholic hallucinosis is a pathological mental state characterized by an acute onset of predominant auditory hallucinations that occur either during or after a period of heavy alcohol consumption. In this study, 52 patients with a diagnosis of Psychotic disorder predominantly hallucinatory associated with alcohol use (F 10.52) were evaluated after a period of three years. Past history of withdrawal hallucinations was associated with alcoholic hallucinosis The study has found a wide spectrum of outcome confirming the earlier observations that alcoholic hallucinosis is a heterogeneous disorder. PMID:21206866

Perme, Bojir; Vijaysagar, Kommu John; Chandrasekharan, R.

2003-01-01

22

Food Service Follow-up Study.  

ERIC Educational Resources Information Center

Bakersfield City College reports on a followup study done to evaluate their Food Service Management Program. The program offers courses in three areas: certification and skill updating for those already employed in school cafeteria work, an A.A. degree program, and avocational courses for extended day students. Identical questionnaires were sent…

Scott, David C.

23

Mary Whitton_SIGGRAPH09 1 Lessons Learned from Ten Years of Studies of Virtual Environments  

E-print Network

Mary Whitton_SIGGRAPH09 1 Lessons Learned from Ten Years of Studies of Virtual Environments User lessons the Effective Virtual Environments (EVE) research team learned while doing a dozen or more studies are organized around and focus on lessons learned in designing, planning, and executing user studies.. #12;Mary

North Carolina at Chapel Hill, University of

24

Prognosis in autism: A follow-up study  

Microsoft Academic Search

A follow-up study involving 85 autistic boys and 35 girls, c. 5 1\\/2 years of age at initial evaluation and 12 years at follow-up, is presented and discussed in considerable detail. Measures, also applied to 26 non-psychotic subnormal controls, included speech, social, educational, and family adequacy ratings, IQ's, and neurological data. Most autistic children remained educationally retarded and 42% were

Marian K. DeMyer; Sandra Barton; William E. DeMyer; James A. Norton; John Allen; Robert Steele

1973-01-01

25

Student Perceptions of Educator Effectiveness: A Follow-Up Study  

ERIC Educational Resources Information Center

The current study investigates graduate student perceptions of educator effectiveness. This study is the follow-up to a pilot and instrument validation study conducted by the researcher. The findings of the previous study indicated student biases in areas such as gender, age, teaching style, learning style, grade awarded, and educator personality…

Sprinkle, Julie E.

2009-01-01

26

FOLLOW UP STUDY OF CHILDREN WITH DEVELOPMENTAL DISABILITIES  

EPA Science Inventory

The Follow-Up Study involves locating and interviewing a group of young adults who, as 10-year-old children, were included in the Metropolitan Atlanta Developmental Disabilities Study, an investigation of the prevalence and risk factors for developmental disabilities that was con...

27

Employer Follow-Up Study: North Carolina Community College System.  

ERIC Educational Resources Information Center

A follow-up study was conducted by the North Carolina Department of Community Colleges in summer 1981 to obtain employer evaluations of the performance of occupational curriculum students who were enrolled in college in the 1979-80 school year, but did not return in 1980-81. Drawing from employment information obtained during the first statewide…

Allred, Marcus D.; Wingfield, Julian C., Jr.

28

Follow-Up Study on the Adjustment of ADHD Adolescence.  

ERIC Educational Resources Information Center

A follow-up investigation evaluated the adolescent outcomes of 10 children with attention deficit hyperactivity disorder who had been treated 5 or more years earlier at a university school clinic with a multimodal treatment program called the Cognitive Academic Social Treatment program. The study hypothesized that adolescents and parents would…

Wacks, Julie M.; Gilman, David Alan

29

NHEXAS PHASE I MARYLAND STUDY--FOLLOW-UP QUESTIONNAIRE DATA  

EPA Science Inventory

The Follow-up questionnaire data set contains information concerning the activities within the household during the sampling week. The information is from 402 follow-up questionnaires for 80 households across 6 cycles. The Follow-up Questionnaire specifically addressed the time ...

30

Adolescent psychological and social predictors of young adult smoking acquisition and cessation: A ten-year longitudinal study  

PubMed Central

Objective A ten-year follow-up study to test the extent to which theory-based adolescent psychological and social factors directly predict and moderate the prediction of young adult smoking acquisition and cessation. Design A prospective community-based sample. A total of 2,970 adolescents participated in the large Washington State Hutchinson Smoking Prevention Project (HSPP) longitudinal cohort. As predictors, psychological factors (i.e., parent-noncompliance, friend-compliance, rebelliousness, achievement motivation, and thrill seeking) and social environmental factors (i.e., parent’s and friend’s smoking) were measured when adolescents were 17–18 years old. Main outcome measures As main outcome measures, smoking acquisition and cessation were assessed both at ages 18 and 28. Results Psychological and social factors predicted 3% to 7% probability (p < .05) of smoking acquisition, and a non-significant to 24% probability (p < .05) of smoking continuation (not quitting) in young adulthood. Both friend-compliance and rebelliousness were more powerful predictors of young adult smoking continuation than of smoking acquisition. Conclusion First evidence that parent non-compliance, friend compliance, and a lack of achievement motivation predict smoking acquisition and (with the exception of parent non-compliance) smoking continuation in young adulthood. Including these psychological factors in future interventions designed to promote young adult smoking cessation may be useful. PMID:21401250

Otten, Roy; Bricker, Jonathan B.; Liu, Jingmin; Comstock, Brian; Peterson, Arthur V.

2013-01-01

31

Medical School Attrition-Beyond the Statistics A Ten Year Retrospective Study  

PubMed Central

Background Medical school attrition is important - securing a place in medical school is difficult and a high attrition rate can affect the academic reputation of a medical school and staff morale. More important, however, are the personal consequences of dropout for the student. The aims of our study were to examine factors associated with attrition over a ten-year period (2001–2011) and to study the personal effects of dropout on individual students. Methods The study included quantitative analysis of completed cohorts and qualitative analysis of ten-year data. Data were collected from individual student files, examination and admission records, exit interviews and staff interviews. Statistical analysis was carried out on five successive completed cohorts. Qualitative data from student files was transcribed and independently analysed by three authors. Data was coded and categorized and key themes were identified. Results Overall attrition rate was 5.7% (45/779) in 6 completed cohorts when students who transferred to other medical courses were excluded. Students from Kuwait and United Arab Emirates had the highest dropout rate (RR?=?5.70, 95% Confidence Intervals 2.65 to 12.27;p?studies). Qualitative analysis revealed recurrent themes of isolation, failure, and despair. Student Welfare services were only accessed by one-third of dropout students. Conclusions While dropout is often multifactorial, certain red flag signals may alert us to risk of dropout including non-EU origin, academic struggling, absenteeism, social isolation, depression and leave of absence. Psychological morbidity amongst dropout students is high and Student Welfare services should be actively promoted. Absenteeism should prompt early intervention. Behind every dropout statistic lies a personal story. All medical schools have a duty of care to support students who leave the medical programme. PMID:23363547

2013-01-01

32

Analyzing the Study of Using Acupuncture in Delivery in the Past Ten Years in China  

PubMed Central

The use of acupuncture in inducing delivery has a long history in China. With progress over time, it has been applied in many aspects. For further study of acupuncture in delivery, this paper analyzed the papers using acupuncture in delivery in the past ten years in mainland China. 87 literatures were picked out by searching relevant electronic databases and bibliographies of relevant journals. The analysis showed randomized controlled trials that were the major type of research, while preclinical researches and literature reviews only account for around ten percent, respectively. Clinical researches indicated that acupuncture can relieve labor pain, promote maternal uterine contraction, shorten birth process, and treat postpartum disorders. Preclinical researches found that acupuncture can adjust certain hormones and improve uterus contraction of late-stage pregnant rats. However, due to lack of large multicenter randomized controlled clinical trials, standardized evaluations of clinical effects in clinical researches and detailed mechanism study in preclinical researches and unequivocal conclusions about the effectiveness, efficacy, and mechanisms of acupuncture in this field cannot be obtained from those researches yet. Further clinical and preclinical studies about the use of acupuncture in delivery with improved methodology is still needed. PMID:24688593

Chen, Yingru; Zhang, Xuekai; Fang, Yigong; Yang, Jinsheng

2014-01-01

33

Colon cancer survival with herbal medicine and vitamins combined with standard therapy in a whole-systems approach: ten-year follow-up data analyzed with marginal structural models and propensity score methods.  

PubMed

Although localized colon cancer is often successfully treated with surgery, advanced disease requires aggressive systemic therapy that has lower effectiveness. Approximately 30% to 75% of patients with colon cancer use complementary and alternative medicine (CAM), but there is limited formal evidence of survival efficacy. In a consecutive case series with 10-year follow-up of all colon cancer patients (n = 193) presenting at a San Francisco Bay-Area center for Chinese medicine (Pine Street Clinic, San Anselmo, CA), the authors compared survival in patients choosing short-term treatment lasting the duration of chemotherapy/radiotherapy with those continuing long-term. To put these data into the context of treatment responses seen in conventional medical practice, they also compared survival with Pan-Asian medicine + vitamins (PAM+V) with that of concurrent external controls from Kaiser Permanente Northern California and California Cancer Registries. Kaplan-Meier, traditional Cox regression, and more modern methods were used for causal inference-namely, propensity score and marginal structural models (MSMs), which have not been used before in studies of cancer survival and Chinese herbal medicine. PAM+V combined with conventional therapy, compared with conventional therapy alone, reduced the risk of death in stage I by 95%, stage II by 64%, stage III by 29%, and stage IV by 75%. There was no significant difference between short-term and long-term PAM+V. Combining PAM+V with conventional therapy improved survival, compared with conventional therapy alone, suggesting that prospective trials combining PAM+V with conventional therapy are justified. PMID:21964510

McCulloch, Michael; Broffman, Michael; van der Laan, Mark; Hubbard, Alan; Kushi, Lawrence; Abrams, Donald I; Gao, Jin; Colford, John M

2011-09-01

34

Colon Cancer Survival With Herbal Medicine and Vitamins Combined With Standard Therapy in a Whole-Systems Approach: Ten-Year Follow-up Data Analyzed With Marginal Structural Models and Propensity Score Methods  

PubMed Central

Although localized colon cancer is often successfully treated with surgery, advanced disease requires aggressive systemic therapy that has lower effectiveness. Approximately 30% to 75% of patients with colon cancer use complementary and alternative medicine (CAM), but there is limited formal evidence of survival efficacy. In a consecutive case series with 10-year follow-up of all colon cancer patients (n = 193) presenting at a San Francisco Bay-Area center for Chinese medicine (Pine Street Clinic, San Anselmo, CA), the authors compared survival in patients choosing short-term treatment lasting the duration of chemotherapy/radiotherapy with those continuing long-term. To put these data into the context of treatment responses seen in conventional medical practice, they also compared survival with Pan-Asian medicine + vitamins (PAM+V) with that of concurrent external controls from Kaiser Permanente Northern California and California Cancer Registries. Kaplan-Meier, traditional Cox regression, and more modern methods were used for causal inference—namely, propensity score and marginal structural models (MSMs), which have not been used before in studies of cancer survival and Chinese herbal medicine. PAM+V combined with conventional therapy, compared with conventional therapy alone, reduced the risk of death in stage I by 95%, stage II by 64%, stage III by 29%, and stage IV by 75%. There was no significant difference between short-term and long-term PAM+V. Combining PAM+V with conventional therapy improved survival, compared with conventional therapy alone, suggesting that prospective trials combining PAM+V with conventional therapy are justified. PMID:21964510

McCulloch, Michael; Broffman, Michael; van der Laan, Mark; Hubbard, Alan; Kushi, Lawrence; Abrams, Donald I.; Gao, Jin; Colford, John M.

2014-01-01

35

NHEXAS PHASE I ARIZONA STUDY--FOLLOW-UP QUESTIONNAIRE DATA  

EPA Science Inventory

The Follow-up Questionnaire data set provides information concerning the activities within the household during the sampling week. The information is from 774 Follow-up Questionnaires for 320 households. Medication and supplemental dietary information is provided. The Follow-u...

36

Ten years of studies on Maryland's inner Continental Margin and coastal bays  

USGS Publications Warehouse

During the past ten years of the Association of American State Geologists-Mineral Management Service Continental Margins Program, the Maryland Geological Survey investigated the sedimentological, paleontological, stratigraphical and geophysical character of Maryland's inner continental shelf. Based on seismic records and sedimentological analyses completed during the first four years, a late Quaternary stratigraphic model was developed. Five distinct stratigraphic units were identified and described on the Maryland inner shelf. These units represent late Pleistocene interglacial deposits, the oldest of which corresponds to pre-Illinoian (oxygen-isotope stages 7 and/or 9) transgressive shelf sands. Overlying the Q1 unit, the Q2 unit is a 6-meter thick mud sequence of oxygen-isotope stage 5 (128-75 ka) age. Units Q3 and Q4 representing fluvial and leading edge estuarine deposits (oxygen-isotope stages 4, 3 and 2) filled numerous paleochannels that were incised into units Q2 and Q1. Modern trailing-edge transgressive shelf shoals (Unit Q5) discontinuously cap the sequence. The 5th and 6th years studies reported on the economic minerals of surficial and cored sediments. Vibracores collected off the Maryland's shelf during previous studies were analyzed for mineral types and abundances, weight percent of general size fractions, and heavy mineral (HM) content. Mineralogic maturity indices were compiled to correlate the THM and economic heavy minerals (EHM) abundances with position offshore, sediment type, and the indices themselves. For the 7th year, the Maryland Geological Survey re-examined geophysical records and lithological data originally collected by the Army Corps of Engineers to locate and assess beach fill borrow areas for the Ocean City Beach Replenishment Project. Data from 163 vibracores and over 300 kilometers of high-resolution seismic profile records collected off Ocean City, Maryland, supported the stratigraphic model developed by MGS during the first four years of the AASG-MMS program. The Maryland coastal bays became the focus of study during the 8th and 9th years during which seismic records, cores and surficial sediment were collected in Isle of Wight and Assawoman Bays. Shallow pretransgression surface was mapped, relating the existing streams to offshore paleochannels. The tenth year study focused on developing a repository for vibracores collected on Maryland's inner continental shelf.During the past ten years of the Association of American State Geologists-Mineral Management Service Continental Margins Program, the Maryland Geological Survey investigated the sedimentological, paleontological, stratigraphical and geophysical character of Maryland's inner continental shelf. Based on seismic records and sedimentological analysis completed during the first four years, a late quaternary stratigraphic model was developed. Five distinct stratigraphic units were identified and described on the Maryland inner shelf. These units represent late Pleistocene interglacial deposits, the oldest of which corresponds to pre-Illinoian transgressive shelf sands.

Kerhin, R.T.; Conkwright, R.; Wells, D.

1999-01-01

37

Ten-year follow-up after autologous stem cell transplantation of a patient with immunoglobulin light-chain (AL) amyloidosis with deposits in the heart, liver and gastrointestinal tract  

PubMed Central

The prognosis in amyloid light chain (AL)-amyloidosis and multiorgan involvement is poor, with a high-treatment-related mortality after high-dose melphalan and autologous stem cell transplantation (HDM/SCT). Some patients, however, might benefit from the therapy. We report a case of cardiac AL-amyloidosis with multiorgan involvement where the progressive cardiomyopathy was halted after successful treatment with HDM/SCT in 2001. The patient is in an excellent cardiac condition with a good quality of life, receiving treatment with angiotensinogen receptor blockers and a flexible diuretics regimen at follow-up after 10 years. PMID:22688930

Mejhert, Marit; Hast, Robert; Sandstedt, Benngt; Janczewska, Izabella

2011-01-01

38

Quality of life after volar locked plating: a 10-year follow-up study of patients with intra-articular distal radius fractures  

PubMed Central

Background This study aimed to present functional results and patient’s health related quality of life (HRQOL) data ten years after volar locked plate fixation (VPF) of unstable intra-articular distal radial fractures (DRF). Methods Thirty-nine patients with a mean age of sixty-one years were operatively treated with VPF after intra-articular distal radial fractures. They were evaluated two, six, and ten years postoperatively according to the Gartland and Werley score. For subjective evaluation the Short Form 36 (SF-36) and the Disability of Arm, Shoulder and Hand (DASH) questionnaires were adopted. Results Overall, wrist function did not differ significantly two, six and ten years after the operation. Over 90% patients achieved “good” or “excellent” results ten years after surgery according to the Gartland and Werley score. Ten years postoperatively the results of the SF 36 did not differ significantly from the two- and six-year follow-up. Overall findings from the SF-36 did not differ significantly from the data of Austrian and American norm populations. Only in the subscale of mental health (MH) the ten-year follow-up did show significantly poorer results (p?=?0.045) compared to the Austrian norm population. The median DASH scores did not show significant differences during the ten-year follow-up period. Conclusion The ten-year results of this single-center study suggest that operative treatment of intra-articular DRF with volar locked plates is a useful and satisfactory therapy option, both in terms of function and HRQOL. PMID:25059690

2014-01-01

39

Fitting epidemiologic follow-up studies with cumulative damage models.  

PubMed

The use of an extended version of the cumulative damage model to identify and quantify cancer risk arising from a specified exposure is outlined. For this, a strategy to fit the model to individual data coming from epidemiologic follow-up studies is described. Two statistical problems are addressed: first, the regularity of the model has to be ascertained to allow the application of maximum-likelihood and likelihood-ratio methods for parameter estimation and testing. Second, a statistical test has to be found that permits testing goodness of fit in the setting of parameter estimation with individual data. As an example, these methods are applied to the data of a cohort study on mortality among stainless steel welders in the Federal Republic of Germany. The results show that the model fits the data well and confirms a carcinogenic effect of stainless steel welding among welders. Some distinguishing characteristics of the model, especially its prediction of a potentially decreasing relative risk despite ongoing carcinogenic exposure, are discussed. PMID:8204982

Becker, N; Rittgen, W

1994-04-01

40

A case study: Follow-up assessment of facilitated communication  

Microsoft Academic Search

A 6-month follow-up of an individual reported to engage in validated facilitated communication (FC) is presented. Three main issues are addressed: the current status of the individual's FC use, the effect of food reinforcers on his communicative ability, and a comparison of FC to the Picture Exchange Communication System (PECS). Results indicated that the individual did not engage in any

Elliott W. Simon; Patricia M. Whitehair; Donna M. Toll

1996-01-01

41

A STUDY OF PSYCHIATRIC MORBIDITY OF A RURAL COMMUNITY AT AN INTERVAL OF TEN YEARS*  

PubMed Central

SUMMARY A field survey of psychiatric morbidity was conducted in a village by a door to door survey. The survey was repeated after 10 years by the same team and by the same method. The aim was to compare the rates of mental morbidity of the community at the interval of a decade and to trace out during the second survey all the persons - both ill and well - found in the first survey and to assess their mental health status. Though the total morbidity did not change from 1972 to 1982 there was a definite rise in the rates of morbidity of Hysteria and Anxiety showed a slight fall in 1982. The health population of 1972 traced and assessed in 1982 showed a lower rate of morbidity than the total population of 1982. The rate of recovery of the morbid stock assessed after ten years was about 29 % and as many as 14.8% of the morbid people died during this period. This death rate is much higher than that of healthy population assessed after ten years (h.9%). 47.8% of the cases detected in the first survey were found to be ill during the second survey richer with the same diagnosis or with a new diagnosis. PMID:21927173

Nandi, D.N.; Banerjee, G.; Mukherjee, S.P.; Sarkar, Sambhu; Boral, G.C.; Mukherjee, Amitava; Mishra, D.C.

1986-01-01

42

Cervical intraepithelial neoplasia in Jordan: A ten year retrospective cytoepidemiologic study.  

PubMed

Occurrence of cervical intraepithelial neoplasia (CIN) was studied in 10,659 females attending obstetric and gynecology clinics in Jordan. The frequency rate of intraepithelial neoplasia was 1.1% in 7743 Jordanian females and 2916 non-Jordanian residents of younger age during the period from 1982 to 1991 inclusive. The incidence rate in 2649 Jordanian females, selected because they attended only for routine checkup, was 49 per 100,000. There were 121 CIN cases which were graded into Grade I (21%), II (48%) and III (31%) respectively. Histological grading correlated with cytology in 70% of the cases while in the remaining 30%, cytologic underrating by one grade was noted; evidence against any overdiagnosis of CIN in our series. Study of the human papillomavirus (HPV) was outside the scope of this effort. However, circumcision in male partners and marital status were associated with a lower frequency of CIN. Age at marriage and average duration, parity, breast feeding, the contraceptive pill, socioeconomic status and menstrual disorders showed no relationship to the frequency of CIN in our patients. Any differences in the latter between Jordanian and non-Jordanian females are believed due to cultural factors. Conization in 27 cases proved effective at 30 months' follow-up. Occurrence of CIN in Jordanian females appears substantial although much lower than that seen in high incidence zones, while its incidence in the general female population remains to be determined. This study shows for the first time the value of Papanicolaou (Pap) smears in Jordanian females over 20 years of age with special emphasis on those over 35 years of age attending obstetric and gynecology clinics. PMID:17590606

Dajani, Y F; Maayta, U M; Abu-Ghosh, Y R

1995-07-01

43

Religiosity and Major Depression in Adults at High Risk: A Ten-Year Prospective Study  

PubMed Central

Objective Previously the authors found that personal importance of religion or spirituality was associated with a lower risk for major depression in a study of adults with and without a history of depression. Here the authors examine the association of personal importance of religion or spirituality with major depression in the adult offspring of the original sample using a 10-year prospective longitudinal design. Method Participants were 114 adult offspring of depressed and nondepressed parents, followed longitudinally. The analysis covers the period from the 10-year to the 20-year follow-up assessments. Diagnosis was assessed with the Schedule for Affective Disorders and Schizophrenia–Lifetime Version. Religiosity measures included personal importance of religion or spirituality, frequency of attendance at religious services, and denomination (all participants were Catholic or Protestant). In a logistic regression analysis, major depression at 20 years was used as the outcome measure and the three religiosity variables at 10 years as predictors. Results Offspring who reported at year 10 that religion or spirituality was highly important to them had about one-fourth the risk of experiencing major depression between years 10 and 20 compared with other participants. Religious attendance and denomination did not significantly predict this outcome. The effect was most pronounced among offspring at high risk for depression by virtue of having a depressed parent; in this group, those who reported a high importance of religion or spirituality had about one-tenth the risk of experiencing major depression between years 10 and 20 compared with those who did not. The protective effect was found primarily against recurrence rather than onset of depression. Conclusions A high self-report rating of the importance of religion or spirituality may have a protective effect against recurrence of depression, particularly in adults with a history of parental depression. PMID:21865527

Miller, Lisa; Wickramaratne, Priya; Gameroff, Marc J.; Sage, Mia; Tenke, Craig E.; Weissman, Myrna M.

2013-01-01

44

Follow Up Study of Group Counseling with Underachieving College Freshmen.  

ERIC Educational Resources Information Center

The purpose of this study was to report long-range effects of group counseling and the college growth experience of students who were identified as underachievers and were enrolled as freshmen during the fall of 1969. Five variables were selected for this study as having possible influence on self-concept: (1) group, (2) education, (3) status, (4)…

Valine, Warren J.

45

A Follow-Up Study of the Registered Nursing Program.  

ERIC Educational Resources Information Center

A followup study of the 1966 and 1967 graduates of the registered nurses program at Foothill College (Calif.) sought to identify characteristics which distinguished students who completed the program from those who did not graduate, analyze scores on the state licensing examination for the licensing of nurses to determine what significant…

Keene, James W.

46

MCC Instruction in Sustainable Technologies. Follow-Up Study.  

ERIC Educational Resources Information Center

The purposes of this study were to collect feedback from Sustainable Technologies interns regarding the usefulness and effectiveness of their education and training from the Maui Community College Instruction in Sustainable Technologies (MIST) program, and to further assess community need for a new Associate Degree program in Sustainable…

Pezzoli, Jean A.; Ainsworth, Donald

47

FINAL REPORT: NATIONAL CHILDREN'S STUDY FOCUS GROUPS - FOLLOW-UP  

EPA Science Inventory

The purpose of this work assignment was to add to our knowledge of the issues that will affect recruitment and retention of pregnant women into the National Children's Study by conducting 14 focus groups comprised of pregnant women, couples, and parents of young chi...

48

A Follow-Up Study of Non-Returning Students.  

ERIC Educational Resources Information Center

In spring 1987, a study was conducted at Monroe Community College (MCC) to determine the factors which influence attrition and retention, with particular focus on the reasons why students who have not graduated fail to return for succeeding semesters. Questionnaires were mailed to 452 former students, requesting information on students' rankings…

Cotnam, John D.; Ison, Sherrill

49

Roxbury Community College Transfer Follow-Up Study.  

ERIC Educational Resources Information Center

In 1984, a study was conducted to gather information regarding the rates and patterns of student transfer from Roxbury Community College (RCC) to four-year institutions. Information on the 178 students who graduated from RCC in 1981 and 1982 was obtained from the RCC Registrar's office and the four-year institutions in Massachusetts to which…

McCartan, Anne-Marie; Rodriguez, Kyrsis R.

50

Follow-Up Study of 1986 Graduates. Evaluation Report.  

ERIC Educational Resources Information Center

A study was conducted to determine the status of the 706 students who graduated from Saginaw and Arthur Hill High Schools in Saginaw, Michigan, in June of 1986. A 13-item questionnaire was mailed to each student on November 21, 1986. Three additional contacts were attempted in an effort to reach nonresponding graduates. A total of 455 graduates…

Saginaw Public Schools, MI. Dept. of Evaluation Services.

51

Kansas Regents Honors Academy: A Follow-Up Study.  

ERIC Educational Resources Information Center

This study examined the impact of the Kansas Regents Honors Academy on students who had completed the program since its inception in 1986. A total of 504 of the approximately 1,640 academically superior graduating high school students completed a survey questionnaire that focused on demographic data, college data (degrees, majors, grade point…

Glennen, Robert E.; Martin, David J.

52

A follow-up study of synthetic rubber workers  

Microsoft Academic Search

Although 1,3-butadiene (BD) has been classified as an animal carcinogen, epidemiologic research has reported inconsistent results on the relationship between BD and lymphopoietic and other cancers in humans. This study evaluated the mortality experience of 15649 men employed for at least 1 year at any of eight North American styrene-butadiene rubber (SBR) plants. About 75% of the subjects were exposed

Elizabeth Delzell; Nalini Sathiakumar; Mary Hovinga; Maurizio Macaluso; Jim Julian; Rodney Larson; Philip Cole; David C. F. Muir

1996-01-01

53

[Treatment follow-up of transsexual patients. A catamnestic study].  

PubMed

In a retrospective study, 33 transsexual patients, 22 male-to-female transsexual (MF-TS), and 11 female-to-male transsexuals (FM-TS), were interviewed 53-121 months after their first referral to the psychiatric department of a university hospital. Social integration proved to be satisfactory and relatively stable. Twenty-five patients had gone through surgical sex reassignment, while 29 were currently undergoing hormonal treatment. Regarding the course of treatment, the FM-TS were a more homogeneous group than the MF-TS group. Overall, physical and psychosocial well-being was satisfactory. Psychometric measures yielded remarkably normal values, with some pathological findings regarding personality traits. In the majority of patients, self- and observer-rating appraisals of gender-specific physical appearance were equally positive. The results suggest a three-step procedure for the treatment of transsexual patients, as is practiced in other centers within German speaking continental Europe. PMID:11963265

Hepp, U; Klaghofer, R; Burkhard-Kübler, R; Buddeberg, C

2002-03-01

54

Self-Report Stability of Adolescent Cigarette Use across Ten Years of Panel Study Data  

ERIC Educational Resources Information Center

This study is the first to examine adolescent cigarette report stability over 10 years. Six waves of data were utilized from the National Longitudinal Survey of Youth. This study examined internal/logical consistency and external consistency. Report stability was higher for lifetime use reports than the age of onset reports. Wave-by-wave…

Shillington, Audrey M.; Reed, Mark B.; Clapp, John D.

2010-01-01

55

A Ten-Year Study on Quantity, Quality and Personal Characteristics of Teacher Candidates.  

ERIC Educational Resources Information Center

A study compares the quantity, quality, and personal characteristics of teacher education candidates for the 1982-83 school year with the teacher education candidates for the 1971-72 and 1972-73 school years. Subjects included students of secondary education at Indiana State University (ISU) who had applied to student teach. Data for the study

Horton, Daniel, Jr.; Summers, Jerry

56

Ten-Year Advance Study of Bethany Nazarene College: Final Report.  

ERIC Educational Resources Information Center

This document presents the final report of a 3-year self-study of Bethany Nazarene College which focuses on self-evaluation and planning for the decade of the 70's. Seven areas were studied: philosophy and objectives, instruction, students, faculty, physical facilities, business and finance, and administration. A steering committee developed…

Ladd, Forrest E.

57

A Ten-year Retrospective Study of Tetanus at a Teaching Hospital in Bangladesh  

Microsoft Academic Search

Summary: Aims: To study the demographic, clinical features, treatment as well as outcomes of tetanus patients in the Bangladeshi population from 1994 to 2003. Design: A retrospective descriptive study. Setting: A large public Medical college hospital with a regional as well as referral service. Materials and Methods: All cases of tetanus in adult patients from January 1994 to December 2003

AHM Feroz; MH RAHMAN

2007-01-01

58

Follow-up Study of Patients With Cerebral Palsy  

PubMed Central

Of 319 patients with cerebral palsy recalled for reevaluation 15 years after the initial visit, 10 percent had died. Of the living, 55 percent had spasticity, 32 percent had athetosis, 4 percent had ataxia and 9 percent had mixed spasticity and athetosis; 38 percent had an intelligence quotient (IQ) less than 50, 24 percent between 50 and 79, and 38 percent had IQ above 80. There was a high correlation between overall functional outcome and intellectual level. Severity of physical disability, as measured by hand use, mobility and speech, also correlated with dependence, in part because increased severity of the disability was associated with decreased intellectual capacity generally. Twenty-five years after the initial visit, parental attitudes and personality intactness were evaluated (using the Minnesota Multiphasic Personality Inventory [MMPI]) and were correlated with satisfaction with status in life in 28 persons predicted to be independent on the 15-year study. Twenty (72 percent) of the 28 were satisfied with their status in life and of these, 16 were evaluated (with the MMPI) with 70 percent scoring in the normal range; 13 (65 percent) had parents with a positive attitude. Positive attitude was defined as parental feelings that the handicapped child was a worthy, valuable person, to be encouraged and assisted but not isolated from the world of nonhandicapped people. Careful serial assessment by professional teams combined with repeated long-term counseling of families can result in optimal outcome for the disability level involved, due to the primary role parents play in the development of a child's character and behavior. PMID:154207

Cohen, Peter; Kohn, Jean G.

1979-01-01

59

Ten-Year Trend Analysis of Autism Severity: A Nationwide Population-Based Register Study  

ERIC Educational Resources Information Center

The severity of autism spectrum disorder was strongly related to the education and service outcome. Without a clear profile of autistic population and its change, efforts to understand its nature and improve the quality of service or education will be impossible. The present study aims to describe the over time reported rate of autism severity…

Lin, Jin-Ding; Sung, Chang-Lin; Lin, Lan-Ping; Hsu, Shang-Wei; Chien, Wu-Chien; Su, Sui-Lung; Wu, Jia-Ling

2011-01-01

60

Azo dyes and related compounds as important aquatic contaminants: a ten-year case study  

EPA Science Inventory

Mutagenicity has been found in several aquatic systems in the world; however, this activity usually is not associated with any of the compounds that are currently regulated. Attempting to identify these hazardous compounds, an integrated study was conducted, employing several dif...

61

The RAND Change Agent Study Ten Years Later: Macro Perspectives and Micro Realities.  

ERIC Educational Resources Information Center

From 1973 to 1978, the Rand Corporation conducted a national study of local public schools' responses to various federal programs requiring educational change--Title III of the 1965 Elementary and Secondary Education Act (ESEA), Title VII of the ESEA, programs financed by the 1968 Vocational Education Act, and the Right-to-Read program. This paper…

McLaughlin, Milbrey Wallin

62

A ten-year study of meroplankton in North Carolina estuaries: Amphipods  

Microsoft Academic Search

Occurrence of gammarid and caprellid amphipods in semimonthly nocturnal surface plankton samples taken on flood tide for 10\\u000a years at one estuarine station and shorter periods at 11 other stations is summarized on a monthly basis. Fifty-eight species\\u000a are identified from samples taken during the study but no single station produced this variety. The great diversity of species\\u000a from stations

Austin B. Williams; Kenneth H. Bynum

1972-01-01

63

Study Results from the Clinical Trials Network’s First Ten Years: Where Do They Lead?  

PubMed Central

The National Drug Abuse Treatment Clinical Trials Network (CTN) began in 2000 with the goal of “improv[ing] the quality of drug abuse treatment throughout the country using science as the vehicle.” Since then, 24 discrete clinical trials were launched, 20 are completed, and 15 have published main outcome papers. Of the latter, four tested pharmacological treatment, eight, psychosocial/behavioral treatment, one, a combination of medication and counseling, and two targeted HIV/HCV risk behavior. We review main study findings for these trials, including treatment retention, substance use or risk behavior outcomes, and secondary outcomes when analyzed. The purpose of this review is to identify the incremental progress toward improving drug treatment made by these trials and to propose next steps for the CTN and for the field arising from these studies. The CTN provides a unique opportunity to systematically design trials that incorporate treatment improvements from previous trials and to direct efforts toward innovations most likely to be incorporated into practice. PMID:20307792

Wells, Elizabeth A.; Saxon, Andrew J.; Calsyn, Donald A.; Jackson, Thomas R.; Donovan, Dennis M.

2010-01-01

64

Ten-Year Cumulative Incidence of Diabetic Retinopathy. The Beijing Eye Study 2001/2011  

PubMed Central

Objective To assess the cumulative 10-year incidence of diabetic retinopathy (DR) and its associated factors in a population living in Greater Beijing. Methods The population-based longitudinal Beijing Eye Study, which included 4439 subjects (age in 2001: 40+years) in 2001, was repeated in 2011 with 2695 subjects participating (66.4% of the survivors). The study participants underwent a detailed ophthalmic examination. Fundus photographs were examined for the new development of DR. Results After excluding individuals with DR at baseline (n?=?87) or no sufficient fundus photographs in 2011 (n?=?6), the study included 2602 subjects with a mean age of 64.6±9.7 years (median: 64.0 years; range: 50 to 93 years). In the 10-year period, 109 subjects (39 men) developed new DR with an incidence of 4.2% (95% confidence interval (CI): 3.45,5.03). In multiple logistic regression analysis, incident DR was significantly associated with higher HbA1c value (P<0.001; Odds Ratio (OR): 1.73; 95% Confidence Interval (CI): 1.35,2.21), longer duration of diabetes mellitus (P<0.001; OR: 1.16; 95% CI: 1.10,1.22), higher serum concentration of creatinine (P?=?0.02; OR: 1.01; 95% CI: 1.002,1.022), lower educational level (P?=?0.049; OR: 0.74; 95% CI: 0.55,0.99), higher estimated cerebrospinal fluid pressure (P?=?0.038; OR: 1.10; 95% CI: 1.01,1.22), and shorter axial length (P<0.001; OR: 0.48; 95% CI: 0.33,0.71). Conclusions The cumulative 10-year incidence (mean: 4.2%) of DR in a North Chinese population was significantly associated with a higher HbA1c value, longer known duration of diabetes mellitus, higher estimated CSFP and shorter axial length (P<0.001). Shorter axial length (or hyperopia) and, potentially, higher CSFP may be additional risk factors to be taken into account when counseling and treating patients with diabetes mellitus. PMID:25347072

Xu, Jie; Xu, Liang; Wang, Ya Xing; You, Qi Sheng; Jonas, Jost B.; Wei, Wen Bin

2014-01-01

65

Evaluating the Cause of Death in Obese Individuals: A Ten-Year Medical Autopsy Study  

PubMed Central

Background. Obesity is a growing public health problem associated with increased morbidity and rate of death. Postmortem examination is imperative to determine the cause of death, to detect clinically unsuspected disease entities, and consequently to determine the actual impact of obesity on patient mortality. Methods. A total of 849 adult autopsies were retrospectively reviewed. Obese (BMI ? 30?kg/m2) and nonobese patients were separately studied. The primary cause of death in each group was categorized into malignancy, infection, stroke, ischemic and nonischemic heart disease, pulmonary embolism, hemorrhage, and primary nonneoplastic diseases of different organ systems. Results. Of 849 autopsies, 32.3% were obese. The leading causes of death in the obese population were malignancy (31.4%), infection (25.9%), ischemic heart disease (12.8%), and pulmonary embolism (6.2%). Obese individuals were statistically more likely to die from pulmonary embolism and liver disease and less likely to die from neurologic diseases and nonischemic heart disease. Conclusion. Autopsies on obese individuals constitute a third of all adult medical autopsies in our center. Increased death rates in the obese due to pulmonary embolism and liver disease should receive special clinical attention. Autopsy findings in the obese population should contribute to overall premortem disease detection, prevention, and management. PMID:25653872

Saab, Jad; Salvatore, Steven P.

2015-01-01

66

Ten-Year Retrospective Longitudinal-Study of Student Perspectives on Value of REU  

NASA Astrophysics Data System (ADS)

For more than two decades, federal agencies have been enthusiastically supporting summer research experiences for undergraduates. These REU programs are tacitly intended to increase retention and provide "an important educational experience" for undergraduates, particularly women, minorities and underrepresented groups. Numerous authors (viz., Laursen, Lopatto, Dolan, among many others) have enthusiastically described positive impacts of summer REU programs from exit interview data. These results include enhanced persistence to pursue STEM careers and confirmed desire to attend graduate school in the field targeted by a particular REU. Perhaps surprisingly, negative student experiences are rarely described in the scholarly literature, but do appear in more informal publications (viz., Gueterma, 2007). One wonders how REU alumni, looking back over their entire collective portfolio of experiences, now perceive the educational value of their REU experience relative to their other educational experiences. To obtain a backwards-looking, reflective description from REU alumni on the value of their REU experiences, we conducted a 10-year, two-stage study was designed to explore the ways in which the REU acted as an educational experience for 51 women from a single geoscience sub-discipline. The first phase was an ex post facto longitudinal analysis of data, including multiple interviews with each participant during their REU, annual open-ended alumni surveys, faculty interviews, and extensive field notes, over a 10-year period. This analysis informed the second phase, a clinical interview. Over 10 hours of interviews with 8 participants were conducted and analyzed. These 8 participants were selected to represent a variety of career stages, and for their potential to reflect on a wide variety of educational experiences. Results from the interviews, done many years after their REU experience, indicate that the interviewees' REU did not provide a substantive educational experience related to the nature of scientific work, the scientific process, or the culture of academia when considered in a comparative context of students' other educational experiences. Results further indicated that the REU did not serve to transform participants' conceptions about themselves as situated in science, and learning gains with regard to other aspects of the self, were somewhat limited. Instead, the data suggests that these women arrived at the REU with pre-existing and remarkably strong conceptions in these areas, and that the REU did not functional to alter those states. These conceptions were frequently the result of interactions with mentors/scientists from middle school until well into the undergraduate period.

Slater, T. F.; Slater, S. J.

2013-12-01

67

Prognosis of Transient Global Amnesia: A Long-Term Follow-Up Study  

Microsoft Academic Search

A long-term follow-up study was performed on patients with transient global amnesia (TGA) in order to evaluate the prognosis, the recurrence rate and the occurrence of stroke and dementia. 102 patients (57 women, 45 men; mean age 62.8 ± 9.4 years) were prospectively included and followed up. The follow-up duration ranged between 12 and 241 months with an average value

C. Gandolfo; C. Caponnetto; M. Conti; N. Dagnino; M. Del Sette; A. Primavera

1992-01-01

68

Follow-Up Studies in Nursing: A Case for Determining Whether Program Objectives Are Achieved.  

ERIC Educational Resources Information Center

A follow-up study of graduates from St. Mary's Junior College (Minnesota) associate degree nursing program is used to demonstrate a multi-trait, multi-method basis for arriving at faculty judgments about the outcomes of a program. The follow-up study attempted to determine: (1) graduates' and employing agencies' perceptions of competencies four…

LaBelle, Beverly M.; Egan, Ellen C.

69

NHEXAS PHASE I REGION 5 STUDY--FOOD FOLLOW-UP QUESTIONNAIRE DATA  

EPA Science Inventory

This data set includes responses for 163 food follow-up questionnaires. The food diary follow-up questionnaire was used to identify how the dietary patterns observed for study participants who had submitted duplicate diet samples and completed the associated food diary related to...

70

Follow-Up Study of 1980 Career Alumni. Volume XI, No. 20.  

ERIC Educational Resources Information Center

In 1981, a follow-up study of 1979-80 students in William Rainey Harper College's (WRHC's) career programs was conducted to gather information about former students' employment and/or educational status and to obtain their evaluations of WRHC's programs and services. After two questionnaire mailings and a telephone follow-up of 681 former…

Lucas, John A.

71

Career Program Completers. 1989-90 Long-Term Follow-Up Study.  

ERIC Educational Resources Information Center

In summer 1994, a long-term follow-up study was conducted of 1989-90 graduates of career programs at Johnson County Community College (JCCC) in Kansas. A survey was mailed to 536 graduates, certificate holders, and students who left JCCC with marketable skills to assess their satisfaction with JCCC and their jobs. With telephone follow-up, a…

Johnson County Community Coll., Overland Park, KS. Office of Institutional Research.

72

NHEXAS PHASE I REGION 5 STUDY--FOLLOW-UP QUESTIONNAIRE DATA (ALL MONITORING PERIODS)  

EPA Science Inventory

This data set includes responses for 249 participants with a total of 444 follow-up questionnaires. Some participants were studied for more than one monitoring period. The Follow-up Questionnaire was used to provide information on relatively infrequent (e.g., less than daily) ac...

73

Cohort profile of the Japan Collaborative Cohort Study at final follow-up.  

PubMed

The Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study) was established in the late 1980s to evaluate the risk impact of lifestyle factors and levels of serum components on human health. During the 20-year follow-up period, the results of the study have been published in almost 200 original articles in peer-reviewed English-language journals. However, continued follow-up of the study subjects became difficult because of the retirements of principal researchers, city mergers throughout Japan in the year 2000, and reduced funding. Thus, we decided to terminate the JACC Study follow-up at the end of 2009. As a final point of interest, we reviewed the population registry information of survivors. A total of 207 (0.19%) subjects were ineligible, leaving 110 585 eligible participants (46 395 men and 64 190 women). Moreover, errors in coding date of birth and sex were found in 356 (0.32%) and 59 (0.05%) cases, respectively, during routine follow-up and final review. Although such errors were unexpected, their impact is believed to be negligible because of the small numbers relative to the large total study population. Here, we describe the final cohort profile at the end of the JACC Study along with selected characteristics of the participants and their status at the final follow-up. Although follow-up of the JACC Study participants is finished, we will continue to analyze and publish study results. PMID:23583921

Tamakoshi, Akiko; Ozasa, Kotaro; Fujino, Yoshihisa; Suzuki, Koji; Sakata, Kiyomi; Mori, Mitsuru; Kikuchi, Shogo; Iso, Hiroyasu; Sakauchi, Fumio; Motohashi, Yutaka; Tsuji, Ichiro; Nakamura, Yosikazu; Mikami, Haruo; Kurosawa, Michiko; Hoshiyama, Yoshiharu; Tanabe, Naohito; Tamakoshi, Koji; Wakai, Kenji; Tokudome, Shinkan; Hashimoto, Shuji; Wada, Yasuhiko; Kawamura, Takashi; Watanabe, Yoshiyuki; Miki, Tsuneharu; Date, Chigusa; Kurozawa, Yoichi; Yoshimura, Takesumi; Shibata, Akira; Okamoto, Naoyuki; Shio, Hideo

2013-01-01

74

Living with faecal incontinence: a 10-year follow-up study.  

PubMed

Faecal incontinence (FI) is a taboo subject, and people living with it can feel stigmatised. This article reports on a 10-year qualitative follow-up to an initial constructivist-grounded theory project, investigating living with FI. This article will also look back at the initial study and the 5-year follow-up study undertaken. The research examines the challenges associated with living with FI and different ways of managing the condition, including the importance of social support. PMID:25757581

Wilson, Mary

2015-03-01

75

Systematic bias in traumatic brain injury outcome studies because of loss to follow-up  

Microsoft Academic Search

Corrigan JD, Harrison-Felix C, Bogner J, Dijkers M, Terrill MS, Whiteneck G. Systematic bias in traumatic brain injury outcome studies because of loss to follow-up. 2003;84:153-60. Objective: To identify potential sources of selection bias created by subjects lost to follow-up in studies of traumatic brain injury (TBI). Design: Demographic, premorbid, injury-related, and hospital course characteristics were compared for subjects lost

John D. Corrigan; Cynthia Harrison-Felix; Jennifer Bogner; Marcel Dijkers; Melissa Sendroy Terrill; Gale Whiteneck

2003-01-01

76

Prospective study of alcoholism treatment in Kuwait: a 5-year follow-up report.  

PubMed

The outcome of a 5-year prospective follow-up study of 100 patients treated in the Kuwait Hospital for alcohol-related problems is reported using two parameters computed from weighted follow-up variables, i.e., Offset Score measuring patients' initial follow-up status and Direction of Slope summarizing consequent follow-up scores. Nineteen patients had died representing 14 times the age-corrected national rate. Univariate and multivariate analyses of outcome measures against prefollow-up patients' characteristics revealed that variables indicating heavy alcohol use independent of each other predicted negative outcome and mortality. The tendency of the group score distribution towards normalization uninfluenced by treatment is demonstrated. The pertinence of these findings to the medical profession in Kuwait is stressed. PMID:2920671

Bilal, A M; Al-Ansari, E A; Kristof, J; Shaltout, A; el-Islam, M F

1989-01-01

77

Adolescents' Declining Motivation to Learn Science: A Follow-Up Study  

ERIC Educational Resources Information Center

This is a mix methods follow-up study in which we reconfirm the findings from an earlier study [Vedder-Weiss & Fortus [2011] "Journal of Research in Science Teaching, 48(2)", 199-216]. The findings indicate that adolescents' declining motivation to learn science, which was found in many previous studies [Galton [2009] "Moving to secondary school:…

Vedder-Weiss, Dana; Fortus, David

2012-01-01

78

The Acculturation of a Group of Lithuanian Women: A Follow-Up Study.  

ERIC Educational Resources Information Center

Presents a study of Lithuanian refugees involving 24 women and spanning 16 years, from the original study done in 1957 in Chicago, to the follow-up study of 14 of the same respondents done in 1973-74. Describes their process of acculturation in different life areas, their attitudes, and their associations. (Executive Office of the AABS, 231 Miller…

Cernius, Vytautas J.

1980-01-01

79

Nursing Education Follow-Up Study--1982 R.N.'s.  

ERIC Educational Resources Information Center

In 1982, a follow-up study of nursing graduates of the Bakersfield College Registered Nursing (RN) program was conducted to obtain information that would lead to improvement in program quality and to a better match between supply and demand in the local nursing labor market. In addition, the study compared results with similar studies conducted…

Scott, David C.

80

Timing of Discharge Follow-up for Acute Pulmonary Embolism: Retrospective Cohort Study  

PubMed Central

Introduction Historically, emergency department (ED) patients with pulmonary embolism (PE) have been admitted for several days of inpatient care. Growing evidence suggests that selected ED patients with PE can be safely discharged home after a short length of stay. However, the optimal timing of follow up is unknown. We hypothesized that higher-risk patients with short length of stay (<24 hours from ED registration) would more commonly receive expedited follow up (?3 days). Methods This retrospective cohort study included adults treated for acute PE in six community EDs. We ascertained the PE Severity Index risk class (for 30-day mortality), facility length of stay, the first follow-up clinician encounter, unscheduled return ED visits ?3 days, 5-day PE-related readmissions, and 30-day all-cause mortality. Stratifying by risk class, we used multivariable analysis to examine age- and sex-adjusted associations between length of stay and expedited follow up. Results The mean age of our 175 patients was 63.2 (±16.8) years. Overall, 93.1% (n=163) of our cohort received follow up within one week of discharge. Fifty-six patients (32.0%) were sent home within 24 hours and 100 (57.1%) received expedited follow up, often by telephone (67/100). The short and longer length-of-stay groups were comparable in age and sex, but differed in rates of low-risk status (63% vs 37%; p<0.01) and expedited follow up (70% vs 51%; p=0.03). After adjustment, we found that short length of stay was independently associated with expedited follow up in higher-risk patients (adjusted odds ratio [aOR] 3.5; 95% CI [1.0–11.8]; p=0.04), but not in low-risk patients (aOR 2.2; 95% CI [0.8–5.7]; p=0.11). Adverse outcomes were uncommon (<2%) and were not significantly different between the two length-of-stay groups. Conclusion Higher-risk patients with acute PE and short length of stay more commonly received expedited follow up in our community setting than other groups of patients. These practice patterns are associated with low rates of 30-day adverse events. PMID:25671009

Vinson, David R.; Ballard, Dustin W.; Huang, Jie; Rauchwerger, Adina S.; Reed, Mary E.; Mark, Dustin G.

2015-01-01

81

Diagnosis delay and follow-up strategies in colorectal cancer. Prognosis implications: a study protocol  

PubMed Central

Background Controversy exists with regard to the impact that the different components of diagnosis delay may have on the degree of invasion and prognosis in patients with colorectal cancer. The follow-up strategies after treatment also vary considerably. The aims of this study are: a) to determine if the symptoms-to-diagnosis interval and the treatment delay modify the survival of patients with colorectal cancer, and b) to determine if different follow-up strategies are associated with a higher survival rate. Methods/Design Multi-centre study with prospective follow-up in five regions in Spain (Galicia, Balearic Islands, Catalonia, Aragón and Valencia) during the period 2010-2012. Incident cases are included with anatomopathological confirmation of colorectal cancer (International Classification of Diseases 9th revision codes 153-154) that formed a part of a previous study (n = 953). At the time of diagnosis, each patient was given a structured interview. Their clinical records will be reviewed during the follow-up period in order to obtain information on the explorations and tests carried out after treatment, and the progress of these patients. Symptoms-to-diagnosis interval is defined as the time calculated from the diagnosis of cancer and the first symptoms attributed to cancer. Treatment delay is defined as the time elapsed between diagnosis and treatment. In non-metastatic patients treated with curative intention, information will be obtained during the follow-up period on consultations performed in the digestive, surgery and oncology departments, as well as the endoscopies, tumour markers and imaging procedures carried out. Local recurrence, development of metastases in the follow-up, appearance of a new tumour and mortality will be included as outcome variables. Actuarial survival analysis with Kaplan-Meier curves, Cox regression and competitive risk survival analysis will be performed. Discussion This study will make it possible to verify if the different components of delay have an impact on survival rate in colon cancer and rectal cancer. In consequence, this multi-centre study will be able to detect the variability present in the follow-up of patients with colorectal cancer, and if this variability modifies the prognosis. Ideally, this study could determine which follow-up strategies are associated with a better prognosis in colorectal cancer. PMID:20920369

2010-01-01

82

Longitudinal changes in white matter following ischemic stroke: a three-year follow-up study.  

PubMed

Information on longitudinal changes in white matter after stroke is limited. The aim of the present study was to quantitatively investigate longitudinal changes in the microstructural integrity of non-lesioned white matter at 1-3 years following ischemic stroke. In a sample of 80 ischemic stroke patients, we obtained diffusion tensor imaging (DTI) measures of fractional anisotropy (FA), an apparent measure of white matter integrity, in radiologically normal-appearing white matter at baseline and 3 years of follow-up. Mixed model regression analysis results showed a significant improvement in FA from baseline during the first 2 years of follow-up that stabilized by the third year of follow-up. These results demonstrate a long-term improvement in apparent white matter integrity following ischemic stroke that continues, at least, into the second year following the insult. PMID:16310892

Wang, Changsheng; Stebbins, Glenn T; Nyenhuis, David L; deToledo-Morrell, Leyla; Freels, Sally; Gencheva, Eugenia; Pedelty, Laura; Sripathirathan, Kumar; Moseley, Michael E; Turner, David A; Gabrieli, John D E; Gorelick, Philip B

2006-12-01

83

Sierra Leone's Former Child Soldiers: A Follow-Up Study of Psychosocial Adjustment and Community Reintegration  

ERIC Educational Resources Information Center

This is the first prospective study to investigate psychosocial adjustment in male and female former child soldiers (ages 10-18; n = 156, 12% female). The study began in Sierra Leone in 2002 and was designed to examine both risk and protective factors in psychosocial adjustment. Over the 2-year period of follow-up, youth who had wounded or killed…

Betancourt, Theresa Stichick; Borisova, Ivelina Ivanova; Williams, Timothy Philip; Brennan, Robert T.; Whitfield, Theodore H.; de la Soudiere, Marie; Williamson, John; Gilman, Stephen E.

2010-01-01

84

Follow-Up Study of 1988 Harper Career Alumni. Volume XVIII, No. 11.  

ERIC Educational Resources Information Center

As part of an ongoing evaluation of the career programs at William Rainey Harper College (WRHC), a follow-up study of 1988 career alumni was conducted and results were compared with previous years. Questionnaires were sent to 517 students who earned 48 or more hours during the 1987-88 academic year at WRHC. Study findings, based on a 75% response…

Lucas, John A.; Meltesen, Cal

85

Follow-Up Study of 1990 Harper College Career Alumni. Volume XX, No. 11.  

ERIC Educational Resources Information Center

As part of an ongoing evaluation of the career programs at William Rainey Harper College (WRHC), in Palatine, Illinois, a follow-up study of 1990 career alumni was conducted and results were compared with previous years. Questionnaires were sent to 599 students who had earned 48 or more hours during the 1989-90 academic year at WRHC. Study

Lucas, J.; Meltesen, C.

86

A Follow-Up Study on Word and Non-Word Reading Skills in Down Syndrome  

ERIC Educational Resources Information Center

The current study was designed to trace changes in the relationship between non-word reading and irregular word reading on the one hand, and between phonological awareness and non-word reading on the other, through a follow-up study of a group of individuals with Down syndrome. Twelve individuals with Down syndrome, whose data were originally…

Roch, Maja; Jarrold, Christopher

2012-01-01

87

Perceived Levels of Cultural Competence for School Social Workers: A Follow-up Study  

ERIC Educational Resources Information Center

The purpose of this article is to report on findings from a follow-up study that examined the relationship among social work education programs, postgraduate professional development, and school social workers' perceived levels of cultural competence in practice with urban minority youth. The initial study demonstrated that African Americans…

Teasley, Martell L.; Archuleta, Adrian; Miller, Christina

2014-01-01

88

Sources of Validity Evidence for Educational and Psychological Tests: A Follow-Up Study  

ERIC Educational Resources Information Center

This study followed up on previous work that examined the incidence of reporting evidence based on test consequences in "Mental Measurements Yearbook". In the present study, additional possible outlets for what has been called "consequential validity" evidence were investigated, including all articles published in the past 10 years in several…

Cizek, Gregory J.; Bowen, Daniel; Church, Keri

2010-01-01

89

Follow-up study using iodine-131 metaiodobenzylguanidine imaging in a patient with neuroblastoma  

SciTech Connect

A new radiopharmaceutical, I-131 metaiodobenzylguanidine (I-131 MIBG) was used to determine the location and to follow-up tumors in a 13-month-old girl with neuroblastoma. I-131 MIBG imaging revealed both a primary abdominal tumor and a distant metastatic orbital tumor. Follow-up study with I-131 MIBG imaging demonstrated significant resolution of tumors after external radiotherapy and chemotherapy. I-131 MIBG imaging is a simple, safe, and specific method of determining the location of tumors and also is clinically useful in the evaluation and management of patients with neuroblastoma.

Ikekubo, K.; Habuchi, Y.; Jeong, S.; Yamaguchi, H.; Saiki, Y.; Ito, H.; Hino, M.; Higa, T.

1986-11-01

90

Dietary changes in Vietnamese marriage immigrant women: The KoGES follow-up study  

PubMed Central

BACKGROUND/OBJECTIVES The immigrant population has grown considerably in South Korea since the early 1990s due to international marriages. Dietary changes in immigrants are an important issue, because they are related to health and disease patterns. This study was conducted to compare changes in dietary intake between baseline and follow-up periods. SUBJECTS/METHODS Two hundreds thirty three Vietnamese female married immigrants. Baseline data were collected during 2006-2009, and the follow-up data were collected during 2008 and 2010. Food consumption was assessed using a 1-day 24-hour recall. RESULTS The amount of the total food consumed (P < 0.001) including that of cereals (P = 0.004), vegetables (P = 0.003), and fruits (P = 0.002) decreased at follow-up compared to that at baseline, whereas consumption of milk and dairy products increased (P = 0.004). Accordingly, the overall energy and nutrient intake decreased at follow-up, including carbohydrates (P = 0.012), protein (P = 0.021), fiber (P = 0.008), iron (P = 0.009), zinc (P = 0.006), and folate (P = 0.002). Among various anthropometric and biochemical variables, mean skeletal muscle mass decreased (P = 0.012), plasma high density lipoprotein-cholesterol increased, (P = 0.020) and high sensitivity C-reactive protein decreased at follow-up (P < 0.001). CONCLUSIONS A long-term follow-up study is needed to investigate the association between changes in food and nutrient intake and anthropometric and biochemical variables in these Vietnamese female marriage immigrants. PMID:24944778

Hwang, Ji-Yun; Lee, Hakim; Ko, Ahra; Han, Chan-Jung; Chung, Hye Won

2014-01-01

91

Dr. Leary's Concord Prison Experiment: a 34-year follow-up study.  

PubMed

This study is a long-term follow-up to the Concord Prison Experiment, one of the best-known studies in the psychedelic psychotherapy literature. The Concord Prison Experiment was conducted from 1961 to 1963 by a team of researchers at Harvard University under the direction of Timothy Leary. The original study involved the administration of psilocybin-assisted group psychotherapy to 32 prisoners in an effort to reduce recidivism rates. This follow-up study involved a search through the state and federal criminal justice system records of 21 of the original 32 subjects, as well as personal interviews with two of the subjects and three of the researchers: Timothy Leary, Ralph Metzner and Gunther Weil. The results of the follow-up study indicate that published claims of a treatment effect were erroneous. This follow-up study supports the emphasis in the original reports on the necessity of embedding psilocybin-assisted psychotherapy with inmates within a comprehensive treatment plan that includes post-release, nondrug group support programs. Despite substantial efforts by the experimental team to provide post-release support, these services were not made sufficiently available to the subjects in this study. Whether a new program of psilocybin-assisted group psychotherapy and post-release programs would significantly reduce recidivism rates is an empirical question that deserves to be addressed within the context of a new experiment. PMID:9924845

Doblin, R

1998-01-01

92

Proportional hazards regression in epidemiologic follow-up studies: an intuitive consideration of primary time scale.  

PubMed

In epidemiologic cohort studies of chronic diseases, such as heart disease or cancer, confounding by age can bias the estimated effects of risk factors under study. With Cox proportional-hazards regression modeling in such studies, it would generally be recommended that chronological age be handled nonparametrically as the primary time scale. However, studies involving baseline measurements of biomarkers or other factors frequently use follow-up time since measurement as the primary time scale, with no explicit justification. The effects of age are adjusted for by modeling age at entry as a parametric covariate. Parametric adjustment raises the question of model adequacy, in that it assumes a known functional relationship between age and disease, whereas using age as the primary time scale does not. We illustrate this graphically and show intuitively why the parametric approach to age adjustment using follow-up time as the primary time scale provides a poor approximation to age-specific incidence. Adequate parametric adjustment for age could require extensive modeling, which is wasteful, given the simplicity of using age as the primary time scale. Furthermore, the underlying hazard with follow-up time based on arbitrary timing of study initiation may have no inherent meaning in terms of risk. Given the potential for biased risk estimates, age should be considered as the preferred time scale for proportional-hazards regression with epidemiologic follow-up data when confounding by age is a concern. PMID:22517300

Cologne, John; Hsu, Wan-Ling; Abbott, Robert D; Ohishi, Waka; Grant, Eric J; Fujiwara, Saeko; Cullings, Harry M

2012-07-01

93

The association between gout and nephrolithiasis in men: The Health Professionals' Follow-Up Study  

Microsoft Academic Search

The association between gout and nephrolithiasis in men: The Health Professionals' Follow-Up Study. Approximately 10 million adults in the United States have experienced the passage of a kidney stone, and up to 5 million have been diagnosed with gout by a physician. Previous reports have suggested that gout increases the risk for the development of kidney stones, but there are

Holly J. Kramer; Hyon K. Choi; Karen Atkinson; Meir Stampfer; Gary C. Curhan

2003-01-01

94

Callosal Tissue Loss in Multiple System Atrophy--A One-Year Follow-Up Study  

E-print Network

, extending posteriorly into the isthmus. Callosal atrophy may possibly reflect a disease-specific pattern of neurodegeneration and cortical atrophy, fitting well with the predominant impair- ment of motor functions in the MSACallosal Tissue Loss in Multiple System Atrophy-- A One-Year Follow-Up Study Martina Minnerop, MD,1

Thompson, Paul

95

A Follow-Up Study of the Oregon Project. Final Report.  

ERIC Educational Resources Information Center

In 1973 the Children's Services Division (Oregon State) initiated a project to reduce the backlog of children in indeterminate status by developing more Permanent alternative placements. This follow-up study evaluates the placements of foster children who returned to their parents, were adopted, or remained in foster care. A literature review…

Lahti, Janet; And Others

96

Five Year Follow-up Evaluation of a Faculty Development Program: A Qualitative Study  

ERIC Educational Resources Information Center

This qualitative follow-up evaluation explored the long-term impact of a faculty development program on participants who were five years post program. This study focused on 12 faculty members who participated in the University of Missouri's New Faculty Teaching Scholars program. The nine month program focused on creating a culture of teaching…

Tennill, Marcia Marie

2011-01-01

97

Methods for Conducting Post-School Outcomes Follow-Up Studies: A Review of the Literature  

ERIC Educational Resources Information Center

The purpose of this brief is to summarize the methodologies and outcome measures used in Post-School Outcomes follow-up and follow-along studies of adolescents with disabilities. As a requisite in the Request for Proposal for funding of the National Post-School Outcomes Center (NPSO), knowledge development activities were to include: "Conducting a…

Alverson, Charlotte Y.; Bayliss, Camilla; Naranjo, Jason M.; Yamamoto, Scott H.; Unruh, Deanne

2006-01-01

98

The relationship between flow experience and sense of coherence: a 1-year follow-up study.  

PubMed

This study examined the relationship between flow experience and sense of coherence in 279 tai chi practitioners aged 67.9 ± 7.9 years, with a 1-year follow-up questionnaire. Our results suggest that tai chi improves sense of coherence in older adults, beginners, and long-term practitioners. PMID:24503746

Iida, Kenji; Oguma, Yuko

2014-01-01

99

A Follow-Up Study of Girls with Gender Identity Disorder  

ERIC Educational Resources Information Center

This study provided information on the natural histories of 25 girls with gender identity disorder (GID). Standardized assessment data in childhood (mean age, 8.88 years; range, 3-12 years) and at follow-up (mean age, 23.24 years; range, 15-36 years) were used to evaluate gender identity and sexual orientation. At the assessment in childhood, 60%…

Drummond, Kelley D.; Bradley, Susan J.; Peterson-Badali, Michele; Zucker, Kenneth J.

2008-01-01

100

The natural course of myasthenia gravis: a long term follow up study  

Microsoft Academic Search

A long term follow up study is presented of 73 patients with myasthenia gravis, living in Amsterdam between 1926 and 1965. In the period 1961-65 the annual incidence was 3.1, the prevalence 53 per million. Maximum severity of the disease occurred during the first seven years after onset in 87%. Eighteen (29%) patients died, of whom eight had a thymoma

H J Oosterhuis

1989-01-01

101

The Preschool Attention-Deficit/Hyperactivity Disorder Treatment Study (PATS) 6-Year Follow-Up  

ERIC Educational Resources Information Center

Objective: To describe the clinical course of attention-deficit/hyperactivity disorder (ADHD) symptom severity and diagnosis from ages 3 to 5 up to 9 to 12 years during a 6-year follow-up after the original Preschool ADHD Treatment Study (PATS). Method: A total of 207 participants (75% male) from the original PATS, assessed at baseline (mean age,…

Riddle, Mark A.; Yershova, Kseniya; Lazzaretto, Deborah; Paykina, Natalya; Yenokyan, Gayane; Greenhill, Laurence; Abikoff, Howard; Vitiello, Benedetto; Wigal, Tim; McCracken, James T.; Kollins, Scott H.; Murray, Desiree W.; Wigal, Sharon; Kastelic, Elizabeth; McGough, James J.; dosReis, Susan; Bauzo-Rosario, Audrey; Stehli, Annamarie; Posner, Kelly

2013-01-01

102

A follow-up study of the fate of small asymptomatic deep venous thromboses  

Microsoft Academic Search

BACKGROUND: Postoperative asymptomatic deep venous thromboses (ADVT) can give rise to posttthrombotic syndrome (PTS), but there are still many unresolved issues in this context. For example, there is a lack of knowledge regarding the fate of small ADVT following minor orthopedic surgery. This follow-up study evaluates postthrombotic changes and clinical manifestations of PTS in a group of patients with asymptomatic

Stefan Rosfors; Lena M Persson; Gerd Lärfars; Lasse J Lapidus

2010-01-01

103

School's Out: A Comprehensive Follow-Up Study on Parents' Perceptions of Their Child's School  

ERIC Educational Resources Information Center

This longitudinal study set out to examine the changes that took place in parents' evaluations of their child's school in the course of the child's complete 9-year-long compulsory education. Over the follow-up period, academically educated and vocationally educated mothers and fathers (N = 326) were asked to indicate their degree of satisfaction…

Raty, Hannu

2010-01-01

104

Follow-Up Study of 1992 Nursing Graduates. Volume XXII, Number 15, March 1994.  

ERIC Educational Resources Information Center

In an attempt to evaluate the effectiveness of its nursing program, William Rainey Harper College (WRHC) (Illinois) conducted a follow-up study of 1992 nursing graduates or alumni. In spring 1993, a survey instrument, inquiring about employment status, future educational plans, and evaluation of their experience at WRHC, was mailed to all 142 WRHC…

Lucas, John A.; Meltesen, Cal

105

Follow-Up Study of 1979-80 Students: North Carolina Community College System.  

ERIC Educational Resources Information Center

A follow-up study of 53,045 occupational curriculum students who left North Carolina community colleges in 1979-80 was conducted to obtain information on students' current employment or educational status, reasons for attending and leaving the colleges, and students' evaluations of the education and services provided. Responses to the 22-item…

Allred, Marcus D.; Wingfield, Julian C., Jr.

106

A Four-Year Follow-Up Study of Underachieving College Freshmen  

ERIC Educational Resources Information Center

A four-year follow-up study of underachieving college freshmen measured changes in the self-concept of those still in college and those who had dropped out. Significant differences generally favored college seniors. Findings also indicate that dropping out of college may be a positive experience. (Author)

Valine, Warren J.

1976-01-01

107

Freshman to Senior Year: A Follow-Up Study of Identity, Narcissism, and Defense Mechanisms  

Microsoft Academic Search

The identity status, narcissism, and use of defense mechanisms of 89 college seniors who had previously been assessed as they entered college (Cramer, 1995) was determined. As compared to earlier follow-up studies, fewer students were found in the Foreclosed status, and more students remained in Moratorium. Support was found for the previously made predictions that change in identity status would

Phebe Cramer

1998-01-01

108

The Literacy Profile of Greek Precocious Readers: A Follow-Up Study  

ERIC Educational Resources Information Center

The aim of this follow-up study was to examine the progress made by 13 Greek-speaking precocious readers in phonological awareness, reading and spelling from the fourth to sixth grades of primary education, and to compare their progress with that of 11 nonprecocious reader classmates. It was hypothesised that because of the linguistic…

Tafa, Eufimia; Manolitsis, George

2012-01-01

109

A Follow-Up Study of the ABRACADABRA Web-Based Literacy Intervention in Grade 1  

ERIC Educational Resources Information Center

This paper reports the follow-up of a randomised control trial study of the ABRACADABRA web-based literacy intervention that contrasted synthetic versus analytic phonics (Comaskey, Savage & Abrami, 2009) in kindergarten children from urban low-SES backgrounds. Participants who received a "synthetic" phonics+phoneme awareness training (n = 26) or…

Di Stasio, Maria Rosaria; Savage, Robert; Abrami, Philip C.

2012-01-01

110

Follow-Up Study of 1983 Legal Technology Graduates. Volume 12, No. 14.  

ERIC Educational Resources Information Center

A follow-up study was conducted at William Rainey Harper College (WRHC) to determine the employment and educational status of graduates of the Legal Technology (LTE) program 6 months after receiving their degree. Attempts were made to contact all 59 1983 LTE graduates for telephone interviews and compare their responses to findings from previous…

Hildebrandt, Sharrie; Lucas, John A.

111

Colorado Even Start Follow-Up Study: Trinidad State Junior College.  

ERIC Educational Resources Information Center

Even Start family literacy programs are integrated adult education, early childhood education, and parent support components intended to break the intergenerational cycle of poverty and low literacy. In Spring of 2002, a follow-up study of one Even Start project was conducted to assess the long-term effects of Even Start programming for families.…

Anderson, Beckie

112

Reversible Autism among Congenitally Blind Children? A Controlled Follow-Up Study  

ERIC Educational Resources Information Center

Background: Atypical forms of autism may yield insights into the development and nature of the syndrome. Methods: We conducted a follow-up study of nine congenitally blind and seven sighted children who, eight years earlier, had satisfied formal diagnostic criteria for autism and had been included in groups matched for chronological age and verbal…

Hobson, R. Peter; Lee, Anthony

2010-01-01

113

A Follow-Up Study of LaGuardia Community College's 1973-1977 Graduates.  

ERIC Educational Resources Information Center

A follow-up study of the graduates of LaGuardia Community College (LCC) classes of 1973 through 1977 was conducted to analyze the salary levels, rates of salary gain over time, employment levels, promotional opportunities, job stability, career paths, and additional education attained by LCC graduates who entered the labor market, continued their…

Weintraub, Jeffrey I.

114

Follow-Up Study of 1988 Nursing Graduates. Volume XVIII, No. 8.  

ERIC Educational Resources Information Center

In 1989, a follow-up study of nursing program graduates was conducted at William Rainey Harper College (WRHC) to examine their employment patterns, further education plans, and evaluate particular aspects of their WRHC experience. Questionnaires were mailed to 105 nursing students who graduated in 1988. Results were compared with previous surveys…

Dincher, J.; Meltesen, Cal

115

Follow-Up Study of 1990 Nursing Graduates. Volume XX, No. 10.  

ERIC Educational Resources Information Center

In 1990, a follow-up study of nursing program graduates was conducted at William Rainey Harper College (WRHC) in Palatine, Illinois, to examine their employment patterns, further education plans, and evaluate particular aspects of their WRHC experience. All 98 nursing students who earned 48 credit hours in 1990 were mailed questionnaires 1 year…

Lucas, J.; Meltesen, C.

116

1985-86 JCCC Career Program Completers: A 3-Year Follow-Up Study.  

ERIC Educational Resources Information Center

In April 1989, a 3-year follow-up study was conducted of students who completed a career program at Johnson County Community College (JCCC),in Kansas, during the 1985-86 academic year to obtain information on their career and educational experiences over an extended period of time. The 385 former students surveyed included career program…

Johnson County Community Coll., Overland Park, KS. Office of Institutional Research.

117

Methods used for successful follow-up in a large scale national cohort study in Thailand  

PubMed Central

Background Ensuring successful follow-up is essential when conducting a prospective cohort study. Most existing literature reviewing methods to ensure a high response rate is based on experience in developed nations. Findings We report our 4-year follow-up success for a national cohort study examining the health transition underway in Thailand. We began the cohort study in 2005 with a baseline postal questionnaire sent to all 200,000 Thais enrolled as distance learning students at Sukhothai Thammathirat Open University and residing all over Thailand; 87,134 or 44% of the students responded. Subsequently we used University and national media to inform cohort members of study progress. Also, we prepared a health book with study results and health advice which was distributed to all cohort members. After 4 years we repeated the survey and achieved a 71% response rate. In this paper we report the methods used to achieve this response The initial follow-up mail-out generated a response rate of about 48% reflecting the extensive preparatory work between baseline and follow-up. After 4 rounds of telephone contact (more than 100,000 phone calls) and 4 related mail-out rounds progressively over 16 months an overall response rate was achieved of just over 71% (n = 60,774). The total cost was US$4.06/respondent - 19% for printing, 21% for postage, 14% for tape measures (included in mail-out), 18% for data processing 22% for prizes and 6% for telephone. Conclusions Many of the methods reported as effective for mail questionnaire and cohort response rates held true for Thailand. These included being associated with a university, incentivating cooperation, follow-up contact, providing a second copy of questionnaire where necessary, and assurance of confidentiality. Telephone contact with the cohort and the small prizes given to responders were particularly important in the Thai context as was Thai leadership of the research team. PMID:21615963

2011-01-01

118

Long-Term Follow-Up Study of Endovascularly Treated Intracranial Aneurysms  

PubMed Central

Summary Long-term follow-up studies after endovascular treatment for intracranial aneurysm are still rare and inconclusive. The aim of this study was to assess the long-term clinical and angiographic outcome of patients with endovascularly treated aneurysms. The clinical outcome of all 185 patients with endovascularly treated aneurysms were analyzed and 77 out of 122 surviving patients were examined with MRI and MRA nine to 16 years (mean 11 years) after the initial endovascular treatment. Sixty-three patients were deceased at the time of follow-up. The cause of death was aneurysm-related in 34 (54?) patients. The annual rebleeding rate from the treated aneurysms was 1.3% in the ruptured group and 0.1% in the unruptured group. In long-term follow-up MRA 18 aneurysms (53%) were graded as complete, 11 aneurysms (32%) had neck remnants and five aneurysms (15%) were incompletely occluded in the ruptured group. The occlusion grade was lower in the unruptured group with 20 aneurysms (41%) graded as complete, 11 (22%) had neck remnants and 18 (37%) were incomplete. However, only three aneurysms were unstable during the follow-up period and needed retreatment. Endovascular treatment of unruptured aneurysms showed incomplete angiographic outcome in 37% of cases. However, the annual bleeding rate was as low as 0.1%. Endovascular treatment of ruptured aneurysms showed incomplete angiographic outcome in 15% of cases and the annual rebleeding rate was 1,3%. PMID:20977853

Pyysalo, L.M.; Keski-Nisula, L.H.; Niskakangas, T.T.; Kähärä, V.J.; Öhman, J.E.

2010-01-01

119

Long-term Follow-up Study of Endovascularly Treated Intracranial Aneurysms  

PubMed Central

Summary Long-term follow-up studies after endovascular treatment for intracranial aneurysm are still rare and inconclusive. The aim of this study was to assess long-term clinical and angiographic outcome of patients with endovascularly treated aneurysms. The Clinical outcome of all 185 patients with endovascularly treated aneurysms were analyzed and 77 out of 122 surviving patients were examined with MRI and MRA nine to 16 years (mean 11 years) after the initial endovascular treatment. Sixty-three patients were deceased at the time of follow-up. The cause of death was aneurysm- related in 34 (54%) patients. The annual re- bleeding rate from the treated aneurysms was 1.3% in the ruptured group and 0.1% in the unruptured group. In long-term follow-up MRA 18 aneurysms (53%) were graded as complete, 11 aneurysms (32%) had neck remnants and five aneurysms (15%) were incompletely occluded in the ruptured group. Occlusion grade was lower in the unruptured group with 20 an- eurysms (41%) graded as complete, 11 (22%) had neck remnants and 18 (37%) were incomplete. However, only three aneurysms were unstable during the follow-up period and needed retreatment. Endovascular treatment of unruptured aneu- rysms showed incomplete angiographic outcome in 37% of cases. However, annual bleeding rate was as low as 0.1%. Endovascular treatment of ruptured aneurysms showed incomplete angiographic outcome in 15% of cases and the annual rebleeding rate was 1.3%. PMID:21162766

Pyysalo, L.M.; Keski-Nisula, L.H.; Niskakangas, T.T.; Kähärä, V.J.; Öhman, J.E.

2010-01-01

120

75 FR 54965 - Proposed Information Collection (Follow-Up Study of a National Cohort of Gulf War and Gulf Era...  

Federal Register 2010, 2011, 2012, 2013, 2014

...AFFAIRS [OMB Control No. 2900-New...Collection (Follow-Up Study of...Management System (FDMS...Titles: Follow-Up Study of...10-0488a. OMB Control Number: OMB Control No. 2900-New...unexplained multi-system illnesses...Burden a. Follow-Up Study...

2010-09-09

121

75 FR 54445 - Proposed Information Collection (Follow-Up Study of a National Cohort of Gulf War and Gulf Era...  

Federal Register 2010, 2011, 2012, 2013, 2014

...AFFAIRS [OMB Control No. 2900-New...Collection (Follow-Up Study of...Management System (FDMS...Titles: Follow-Up Study of...10-0488a. OMB Control Number: OMB Control No. 2900-New...unexplained multi-system illnesses...Burden: a. Follow-Up Study...

2010-09-07

122

A follow-up study of a third-party radiographic evaluation system.  

PubMed

A follow-up study was conducted to evaluate the performance of the rating system for third-party carriers which was developed and instituted in 1976. Further, the technical quality of radiographs submitted under the system was evaluated. The conditions and parameters of the second study were identical to those of the original work. Statistical comparison of the data from both studies shows a significant decrease in the frequency of error occurrences over the 3-year span between the studies. PMID:6576299

Beideman, R W; Pettigrew, J C; Green, P H

1983-07-01

123

Effects of art therapy with prison inmates: A follow-up study  

Microsoft Academic Search

A pilot study conducted to measure the effects of art therapy with prison inmates (Gussak, 2004) demonstrated marked improvement in mood. The results of this study encouraged a quantitative follow-up study the following year. This study used the Formal Elements Art Therapy Scale (FEATS) and the Beck Depression Inventory-Short Form (BDI-II) as pre and post-test assessments to assess the effects

David Gussak

2006-01-01

124

Prediction of medication noncompliance in outpatients with schizophrenia: 2-year follow-up study.  

PubMed

Neuroleptic noncompliance is a major reason for relapse in outpatients with schizophrenia. In a 2-year follow-up study, we used the Japanese version of the Rating of Medication Influences Scale (ROMI-J) to investigate the reasons for compliance and noncompliance in outpatients with schizophrenia. Ninety outpatients who were confirmed by interview to have had good compliance for more than 3 months completed the initial interview, which included the Clinical Global Impressions Scale (CGI), the Brief Psychiatric Rating Scale (BPRS), the Global Assessment of Functioning Scale (GAF), the UKU Side Effect Rating Scale, and the ROMI-J. All the outpatients were followed up for 2 years. At the initial interview, the most frequent reason for compliance was "relapse prevention," while the most frequent reason for noncompliance was "distressed by side effects." Fifteen outpatients who proved to be noncompliant in the follow-up period had higher baseline BPRS "agitation" scores and ROMI-J "no perceived daily benefit" ratings than compliant patients. Sixty-four outpatients who maintained compliance during the follow-up had higher baseline ROMI-J ratings of "fulfillment of life goals" than their noncompliant counterparts. It is important to understand the attitudes of patients with schizophrenia toward drug therapy in order to predict better compliance and provide psychoeducation designed to forestall relapses. PMID:16318875

Yamada, Kazuo; Watanabe, Koichiro; Nemoto, Naoyuki; Fujita, Hidechika; Chikaraishi, Chikayo; Yamauchi, Keita; Yagi, Gohei; Asai, Masahiro; Kanba, Shigenobu

2006-01-30

125

Bilateral dislocation of the hip in spina bifida: a long-term follow-up study.  

PubMed

Nineteen patients with spina bifida and bilateral dislocation of the hips were studied with a minimal follow-up of 10 years. The average age at review was 21 years (range, 10-31). Ten patients had an upper neurologic level (thoracic to L3), and nine had a low lesion (L4 to sacrum). Three patients had no hip surgery. A closed or open reduction was performed in 12 hips, supplemented by one or more surgical procedures. Of these, 10 remained enlocated, and two had redislocated. In all other hips, several surgical procedures were performed, aimed at improvement of hip-flexion deformity or stability. At follow-up, one patient had occasional pain in one hip, which was dysplastic. Of the 10 patients with a high lesion, only two were walkers, but both had bilateral dislocation of the hips at follow-up. In contrast, all nine patients were walkers, but four of these had bilateral dislocation at follow-up. We found that a level pelvis and good range of motion of the hips are more important for ambulation than is reduction of bilateral hip dislocation. PMID:9661846

Heeg, M; Broughton, N S; Menelaus, M B

1998-01-01

126

Working conditions and weight gain: a 28-year follow-up study of industrial employees  

Microsoft Academic Search

Longitudinal studies observing working conditions and weight gain are rare. We aimed to study whether weight gain can be predicted\\u000a by working conditions or changes in them in a 28-year follow-up. The study population consisted of working-aged industrial\\u000a employees (n = 449). Data on height and weight were collected in clinical examinations in 1973, 1983 and 2001, and information on working\\u000a conditions

Tea Lallukka; Sirpa Sarlio-Lähteenkorva; Leena Kaila-Kangas; Janne Pitkäniemi; Ritva Luukkonen; Päivi Leino-Arjas

2008-01-01

127

A 5-year prospective follow-up study of vaginal surgery for pelvic organ prolapse  

Microsoft Academic Search

The objective of this study was to evaluate anatomic, functional, short- and long-term outcome of vaginal surgery for pelvic\\u000a organ prolapse. This was a prospective observational study of 185 consecutive women planned for vaginal prolapse reconstructive\\u000a surgery. Stage of prolapse, urinary incontinence (UI), bowel and mechanical symptoms were assessed preoperatively and at 1,\\u000a 3 and 5 years postoperatively. The mean follow-up

Ann Miedel; Gunilla Tegerstedt; Birgitta Mörlin; Margareta Hammarström

2008-01-01

128

Quality of Life of Breast Cancer Survivors After a Recurrence: A Follow-Up Study  

Microsoft Academic Search

Previous studies on breast cancer recurrence provide a mixed picture of the quality of life of women following a recurrence. To clarify the picture, the present study addresses some previous methodological concerns by offering a multidimensional assessment with follow-up, a matched comparison group of disease-free survivors, and a closer look at the nature of recurrence (local versus metastatic). Fifty-Four of

Sindy Oh; Lara Heflin; Beth E. Meyerowitz; Katherine A. Desmond; Julia H. Rowland; Patricia A. Ganz

2004-01-01

129

A Five Year Follow-Up National Study of Ethics Committees in Medical Organizations in Japan  

Microsoft Academic Search

Compared to institutional and area-based ethics committees, little is known about the structure and activities performed by\\u000a ethics committees at national medical organizations and societies. This five year follow-up study aimed to determine (1) the\\u000a creation and function of ethics committees at medical organizations in Japan, and (2) their general strategies to deal with\\u000a ethical problems. The study sample included

Akira Akabayashi; Brian Taylor Slingsby; Noriko Nagao; Ichiro Kai; Hajime Sato

2008-01-01

130

Pubertal Timing and Substance Use in Middle Adolescence: A 2Year Follow-up Study  

Microsoft Academic Search

Earlier research has associated early puberty with emotional and behavioral symptoms particularly among girls, while among\\u000a boys, findings have been contradictory as to whether risks are associated with early or late pubertal timing. We studied the\\u000a association between pubertal timing and substance use behaviors in middle adolescence in a 2-year follow up study of 2,070\\u000a (mean age 15.5 years, SD 0.36;

Anna-Maija Koivisto; Mauri Marttunen; Sari Fröjd

131

Dimensions of Post-Stroke Fatigue: A Two-Year Follow-Up Study  

Microsoft Academic Search

Background: The aim of this study was to examine the course of poststroke fatigue in a cohort of first-time stroke patients compared to the general population, and to identify clinically relevant features of post-stroke fatigue. Methods: We performed a follow-up study of 165 patients with first-time stroke admitted to acute stroke units at the Aarhus University Hospital, Denmark. A reference

Doris Christensen; Soeren Paaske Johnsen; Torquil Watt; Ingegerd Harder; Marit Kirkevold; Grethe Andersen

2008-01-01

132

Pre-existing Cardiovascular Disease and Periodontitis: A Follow-up Study  

Microsoft Academic Search

Periodontal infections in individuals with pre-existing heart disease are believed to increase the risk for future coronary heart disease (CHD) events. The goal of this study was to search for an association between periodontitis and CHD events among individuals with pre-existing heart disease, reported in the First National Health and Nutrition Examination Survey Epidemiologic Follow-up Study. Dentate adults (n =

P. P. Hujoel; M. Drangsholt; C. Spiekerman; T. A. DeRouen

2002-01-01

133

Replication of genetic linkage by follow-up of previously studied pedigrees  

SciTech Connect

Independent replication of linkage in previously studied pedigrees is desirable when genetic heterogeneity is suspected or when the illness is very rare. When the likelihood of the new data in this type of replication study is computed as conditional on the previously reported linkage results, it can be considered independent. The authors describe a simulation method using the SLINK program in which the initial data are fixed and newly genotyped individuals are simulated under [theta] = .01 and [theta] = .50. These give appropriate lod score criteria for rejection and acceptance of linkage in the follow-up study, which take into account the original marker genotypes in the data. An estimate of the power to detect linkage in the follow-up data is also generated. 13 refs., 1 fig., 1 tab.

Gershon, E.S.; Goldin, L.R. (National Institute of Mental Health, Bethesda, MD (United States))

1994-04-01

134

NHEXAS PHASE I ARIZONA STUDY--STANDARD OPERATING PROCEDURE FOR CODING: FOLLOW UP QUESTIONNAIRE (UA-D-11.0)  

EPA Science Inventory

The purpose of this SOP is to define the coding strategy for the Follow Up Questionnaire. This questionnaire was developed for use in the Arizona NHEXAS project and the "Border" study. Household and individual follow-up data were combined in a single Follow-up Questionnaire data...

135

Compilation of Case Studies: Exemplary Placement and Follow-Up Studies.  

ERIC Educational Resources Information Center

Examples of placement and follow-up conceptual models developed for a program of vocational education (kindergarten through university) are presented. Section 1 contains a historical overview of placement and follow-up activities in Florida and describes a comprehensive model. Section 2, describing a model for utilizing community resources for the…

Dale, Jack

136

A web-based image viewer for multiple PET-CT follow-up studies  

Microsoft Academic Search

There exist many viewers for single-modal medical images that are efficient and are equipped with powerful analysis tools. However, there is a distinct lack of efficient image viewers for multi-modality images, particularly for displaying multiple follow-up studies that depict a patient's response to treatment over time. Such viewers would be required to display large amounts of image data. In this

Daiki Haraguchi; Jinman Kim; Ashnil Kumar; Liviu Constantinescu; Lingfeng Wen; David Dagan Feng

2011-01-01

137

Ceruloplasmin and superoxide dismutase (SOD1) in Parkinson's disease: A follow-up study  

Microsoft Academic Search

In this follow-up study concentration, oxidative activity and specific oxidative activity of ceruloplasmin (CP) in serum and the activity of superoxide dismutase (SOD1) in erythrocytes were reexamined in 28 of originally 40 patients with Parkinson's disease (PD), and their age- and gender-matched controls. The mean CP and SOD1 parameters were significantly lower in the patients than in the controls. SOD1

Gudlaug Tórsdóttir; Sigurlaug Sveinbjörnsdóttir; Jakob Kristinsson; Jón Snaedal; Torkell Jóhannesson

2006-01-01

138

Routine vaccinations and child survival: follow up study in Guinea›Bissau, West Africa  

Microsoft Academic Search

Objective To examine the association between routine childhood vaccinations and survival among infants in Guinea›Bissau. Design Follow up study. Participants 15 351 women and their children born during 1990 and 1996. Setting Rural Guinea›Bissau. Main outcome measures Infant mortality over six months (between age 0›6 months and 7›13 months for BCG; diphtheria, tetanus, and pertussis; and polio vaccines and between

Ines Kristensen; Peter Aaby; Henrik Jensen

139

Depression and psychosocial adjustment in adolescent anorexia nervosa. A controlled 3-year follow-up study  

Microsoft Academic Search

This study investigated depressive psychopathology and psychosocial functioning in adolescent anorexia nervosa patients at a three year follow-up in comparison to healthy age-matched controls. Three standardized rating instruments (HRSD, SDS, BDI) were used for assessing depression and the Morgan-Russell scales for defining the outcome of the eating disorder. Our findings suggest 1) a highly positive correlation between eating disorder and

Beate Herpertz-Dahlmann; Helmut Remschmidt

1993-01-01

140

Meniscus allograft transplantation using posterior peripheral suture technique: a preliminary follow-up study  

Microsoft Academic Search

The aim of this study was to describe the indication, planning, technique, rehabilitation, and clinical results after cryopreserved allograft meniscus transplantation. Forty consecutive patients, 33 men and 7 women (mean, 37.3 years of age), were evaluated at 1-year follow-up post surgery. Symptoms, patient satisfaction, ROM (range of motion), surgical time, blood loss, and surgical history were evaluated. Thirty-eight (95%) patients

Kazumasa Fukushima; Nobuo Adachi; Joon Y. Lee; Vladimir Martinek; Mark Urquhart; Junnosuke Ryu; Freddie H. Fu

2004-01-01

141

Investigations on health hazards of chimney sweeps in Germany: results of a follow-up study  

Microsoft Academic Search

Within the framework of a longitudinal study, 127 chimney sweeps from the area of Upper and Middle Franconia (Bavaria, Germany), who had participated in a first medical check-up in 1974, were offered follow-up examinations in 1990. Eighty-one subjects participated in these examinations; in addition individual occupational case histories and medical case histories were obtained for a further 15 and 35

S. Letzel; A. Weber; K.-H. Schaller; J. Angerer; H. Iro; G. Waitz; F. Knorr-Held; D. Weltle; G. Lehnert

1992-01-01

142

Predictors of weight change in men: Results from The Health Professionals Follow-Up Study  

Microsoft Academic Search

OBJECTIVE: Since the prevalence of adult obesity is increasing in the United States, we examined the effect of changing common habits (exercise, TV viewing, smoking and eating habits) on four year change in body weight.DESIGN: A prospective cohort study of US male health professionals with follow-up from 1988–1992. Participants were 19 478 men aged 40–75 in 1986, who were free

EH Coakley; EB Rimm; G Colditz; I Kawachi; W Willett

1998-01-01

143

Selective mutism: follow-up study 1 year after end of treatment.  

PubMed

Cognitive behavioral therapy (CBT) is generally considered the recommended approach for selective mutism (SM). Prospective follow-up studies of treated SM and predictors of outcome are scarce. We have developed a CBT home and school-based intervention for children with SM previously found to increase speech in a pilot efficacy study and in a randomized controlled treatment study. In the present report we provide outcome data 1 year after having completed the 6-month course of CBT for 24 children with SM, aged 3-9 years (mean age 6.5 years, 16 girls). Primary outcome measures were the teacher rated School Speech Questionnaire (SSQ) and diagnostic status. At follow-up, no significant decline was found on the SSQ scores. Age and severity of SM had a significant effect upon outcome, as measured by the SSQ. Eight children still fulfilled diagnostic criteria for SM, four were in remission, and 12 children were without diagnosis. Younger children improved more, as 78 % of the children aged 3-5 years did not have SM, compared with 33 % of children aged 6-9 years. Treatment gain was upheld at follow-up. Greater improvement in the younger children highlights the importance of an early intervention. PMID:25267381

Oerbeck, Beate; Stein, Murray B; Pripp, Are H; Kristensen, Hanne

2014-09-30

144

Heart rate dynamics in temporal lobe epilepsy-A long-term follow-up study.  

PubMed

The aim of the present study was to prospectively evaluate long-term changes in interictal heart rate variability (HRV) in patients with temporal lobe epilepsy (TLE). A 24-h ECG was recorded at baseline and after a mean follow-up of 6.1 years in 18 patients with refractory TLE and 18 patients with well-controlled TLE. After the follow-up, the Poincaré components SD(1) (p=0.039) and SD(2) (p=0.001) were decreased in patients with refractory TLE compared to baseline, whereas in patients with well-controlled TLE no changes (p>0.05) in HR variability were observed. The reduction in HRV seems to be progressive in patients with chronic refractory TLE with recurrent seizures. PMID:21093218

Suorsa, Eija; Korpelainen, Juha T; Ansakorpi, Hanna; Huikuri, Heikki V; Suorsa, Ville; Myllylä, Vilho V; Isojärvi, Jouko I T

2011-01-01

145

Minor head injury: impact on general health after 1 year. A prospective follow-up study.  

PubMed

A prospective follow-up study of 51 patients hospitalized due to minor head injury (MHI) was performed. After one year 28 patients answered the General Health Questionnaire, the Impact of Event Scale and a symptom checklist. A significant impact on general wellbeing attributed to head injury, was indicated. Half of the patients reported some sequelae from head injury, only 25% to a degree that resulted in a case score on General Health Questionnaire. Incidence of prominent post-traumatic stress symptoms was around 20%. Outcome seemed without correlation to trauma severity. Patients with sequelae after one year reported more symptoms at one week after trauma, and the results point to the magnitude of the health problems due to sequelae throughout follow-up. Aspects of prevention and treatment are discussed. PMID:1546534

Middleboe, T; Andersen, H S; Birket-Smith, M; Friis, M L

1992-01-01

146

The natural history of the rheumatoid shoulder: a prospective long-term follow-up study.  

PubMed

The purpose of this study was to evaluate the natural history of rheumatoid disease of the shoulder over an eight-year period. Our hypothesis was that progression of the disease is associated with a decrease in function with time. A total of 22 patients (44 shoulders; 17 women, 5 men, (mean age 63)) with rheumatoid arthritis were followed for eight years. All shoulders were assessed using the Constant score, anteroposterior radiographs (Larsen score, Upward-Migration-Index (UMI)) and ultrasound (US). At final follow-up, the Short Form-36, disabilities of the arm, shoulder and hand (DASH) Score, erythrocyte sedimentation rate and use of anti-rheumatic medication were determined. The mean Constant score was 72 points (50 to 88) at baseline and 69 points (25 to 100) at final follow-up. Radiological evaluation showed progressive destruction of the peri-articular structures with time. This progression of joint and rotator cuff destruction was significantly associated with the Constant score. However, at baseline only the extent of rotator cuff disease and the UMI could predict the Constant score at final follow-up. A plain anteroposterior radiograph of the shoulder is sufficient to assess any progression of rheumatoid disease and to predict functional outcome in the long term by using the UMI as an indicator of rotator cuff degeneration. PMID:25371467

van der Zwaal, P; Pijls, B G; Thomassen, B J W; Lindenburg, R; Nelissen, R G H H; van de Sande, M A J

2014-11-01

147

Patient relationship management: an overview and study of a follow-up system.  

PubMed

Customer relationship management research is utilized to explain the need for a more patient-oriented support in patient care. This article presents a European study on how various hospital units of a single healthcare organization have utilized a patient relationship management system--in particular a patient treatment follow-up system--and how it affects patient care and the knowledge work performed by the medical staff. Eight physicians were interviewed at a university hospital on whether patient treatment was improved through a follow-up system that had been in use in the case organization for three years. The interviewees represented various hospital units, and all of them had used the system at their own unit. The results indicate that it is possible to improve patient care through more personalized treatment. The follow-up treatment system seems to be a tool to create and maintain better communication with the patients rather than just a technological solution. It may help better understand and analyze both individual patients and patient groups. For individual physicians it provides a way to reflect professional skills. The system was lacking in its support for one-to-one communication with patients. Nevertheless, the system is an example of patient relationship management which may help healthcare units to move towards a more patient-oriented care. PMID:19267028

Oinas-Kukkonen, Harri; Räisänen, Teppo; Hummastenniemi, Niko

2008-01-01

148

Stability of alexithymia in late adolescence: results of a 4-year follow-up study.  

PubMed

The aim of the present study was to assess the stability of alexithymia in adolescents and the effects of parental factors and social support thereon. The sample comprised 315 late adolescents, of whom 259 were female and 56 male. At baseline, the mean age of the subjects was 19 years (range 17-21 years). The follow-up period was 4 years (2008-2012). The 20-item Toronto Alexithymia Scale (TAS-20) was used for the assessment of alexithymia both at baseline and follow-up. The Multidimensional Scale of Perceived Social Support (MSPSS) and the Parental Bonding Instrument (PBI) were used as measures at baseline. Regarding absolute stability, the changes in the TAS-20 total scores and two subscales (DIF and EOT) were statistically significant but the effect sizes for the changes were small (Cohen?s d 0.21-0.24). The test-retest correlations for the TAS-20 total and subscale scores were high (?=0.50-0.64, P<0.001), indicating relative stability. While several parental and social support variables were associated with alexithymia at baseline, low social support from friends was the only to predict higher alexithymia at follow-up. Alexithymia is a stable personality trait also in late adolescence. Low social support from friends is related to alexithymia in young adulthood. PMID:24953425

Karukivi, Max; Pölönen, Tuukka; Vahlberg, Tero; Saikkonen, Suvi; Saarijärvi, Simo

2014-10-30

149

Ceramic-on-Ceramic Total Hip Arthroplasty: Minimum of Six-Year Follow-up Study  

PubMed Central

Background This study examines the clinical and radiologic results of ceramic-on-ceramic total hip arthroplasties with regard to wear, osteolysis, and fracture of the ceramic after a minimum follow-up of six years. Methods We evaluated the results of a consecutive series of 148 primary ceramic-on-ceramic total hip arthroplasties that had been performed between May 2001 and October 2005 in 142 patients. The mean age was 57.2 years (range, 23 to 81 years). The mean follow-up period was 7.8 years (range, 6.1 to 10.1 years). Preoperative diagnosis was avascular necrosis in 77 hips (52%), degenerative arthritis in 36 hips (24.3%), femur neck fracture in 18 hips (12.2%), rheumatoid arthritis in 15 hips (10.1%), and septic hip sequelae in 2 hips (1.4%). Clinical results were evaluated with the Harris hip score, and the presence of postoperative groin or thigh pain. Radiologic analysis was done with special attention in terms of wear, periprosthetic osteolysis, and ceramic failures. Results The mean Harris hip score improved from 58.3 (range, 10 to 73) to 92.5 (range, 79 to 100) on the latest follow-up evaluation. At final follow-up, groin pain was found in 4 hips (2.7%), and thigh pain was found in 6 hips (4.1%). Radiologically, all femoral stems demonstrated stable fixations without loosening. Radiolucent lines were observed around the stem in 25 hips (16.9%), and around the cup in 4 hips (2.7%). Endosteal new bone formation was observed around the stem in 95 hips (64.2%) and around the cup in 88 hips (59.5%). No osteolysis was observed around the stem and cup. There were 2 hips (1.4%) of inclination changes of acetabular cup, 2 hips (1.4%) of hip dislocation, 1 hip (0.7%) of ceramic head fracture, and 1 hip (0.7%) of squeaking. The Kaplan-Meier survival rate of the prostheses was 98.1% at postoperative 7.8 years. Conclusions The ceramic-on-ceramic total hip arthroplasty produced excellent clinical results and implant survival rates with no detectable osteolysis on a minimum six-year follow-up study. The ceramic-on-ceramic couplings could be a reasonable option of primary total hip arthroplasty for variable indications. PMID:24009902

Choy, Won-Sik; Lee, Sang Ki; Bae, Kyoung Wan; Hwang, Yoon Sub; Park, Chang Kyu

2013-01-01

150

Breast Cancer and the Environment on Long Island Follow-up Study  

Cancer.gov

Dr. Marilie Gammon, of the University of North Carolina at Chapel Hill, and collaborating scientists in New York City, conducted a follow-up study on 1,098 women with breast cancer who participated in the parent population-based case-control study of Long Island women. The primary aims of the study were to determine whether environmental and other lifestyle factors influence breast cancer survival and overall survival among a population-based sample of Long Island women diagnosed with the disease.

151

The 'fine structure' of nutrient dynamics in rivers: ten years of study using high-frequency monitoring  

NASA Astrophysics Data System (ADS)

A complete appraisal of material fluxes in flowing waters is really only possibly with high time resolution data synchronous with measurements of discharge. Defined by Kirchner et al. (2004; Hydrological Processes, 18/7) as the high-frequency wave of the future and with regard to disentangling signal noise from process pattern, this challenge has been met in terms of nutrient flux monitoring by automated bankside analysis. In Ireland over a ten-year period, time-series nutrient data collected on a sub-hourly basis in rivers have been used to distinguish fluxes from different catchment sources and pathways and to provide more certain temporal pictures of flux for the comparative definition of catchment nutrient dynamics. In catchments where nutrient fluxes are particularly high and exhibit a mix of extreme diffuse and point source influences, high time resolution data analysis indicates that there are no satisfactory statistical proxies for seasonal or annual flux predictions that use coarse datasets. Or at least exposes the limits of statistical approaches to catchment scale and hydrological response. This has profound implications for catchment monitoring programmes that rely on modelled relationships. However, using high resolution monitoring for long term assessments of catchment mitigation measures comes with further challenges. Sustaining continuous wet chemistry analysis at river stations is resource intensive in terms of capital, maintenance and quality assurance. Furthermore, big data capture requires investment in data management systems and analysis. These two institutional challenges are magnified when considering the extended time period required to identify the influences of land-based nutrient control measures on water based systems. Separating the 'climate signal' from the 'source signal' in river nutrient flux data is a major analysis challenge; more so when tackled with anything but higher resolution data. Nevertheless, there is scope to lower costs in bankside analysis through technology development, and the scientific advantages of these data are clear and exciting. When integrating its use with policy appraisal, it must be made clear that the advances in river process understanding from high resolution monitoring data capture come as a package with the ability to make more informed decisions through an investment in better information.

Jordan, Phil; Melland, Alice; Shore, Mairead; Mellander, Per-Erik; Shortle, Ger; Ryan, David; Crockford, Lucy; Macintosh, Katrina; Campbell, Julie; Arnscheidt, Joerg; Cassidy, Rachel

2014-05-01

152

U.S.-MEXICO BORDER PROGRAM ARIZONA BORDER STUDY--FOLLOW-UP QUESTIONNAIRE DATA  

EPA Science Inventory

The Follow-up Questionnaire data set provides information concerning the activities within the household during the sampling week. The information is from 201 Follow-up Questionnaires for 91 households. Medication and supplemental dietary information is provided. The Follow-up...

153

CORONIS - International study of caesarean section surgical techniques: the follow-up study  

PubMed Central

Background The CORONIS Trial was a 2×2×2×2×2 non-regular, fractional, factorial trial of five pairs of alternative caesarean section surgical techniques on a range of short-term outcomes, the primary outcome being a composite of maternal death or infectious morbidity. The consequences of different surgical techniques on longer term outcomes have not been well assessed in previous studies. Such outcomes include those related to subsequent pregnancy: mode of delivery; abnormal placentation (e.g. accreta); postpartum hysterectomy, as well as longer term pelvic problems: pain, urinary problems, infertility. The Coronis Follow-up Study aims to measure and compare the incidence of these outcomes between the randomised groups at around three years after women participated in the CORONIS Trial. Methods/Design This study will assess the following null hypotheses: In women who underwent delivery by caesarean section, no differences will be detected with respect to a range of long-term outcomes when comparing the following five pairs of alternative surgical techniques evaluated in the CORONIS Trial: 1. Blunt versus sharp abdominal entry 2. Exteriorisation of the uterus for repair versus intra-abdominal repair 3. Single versus double layer closure of the uterus 4. Closure versus non-closure of the peritoneum (pelvic and parietal) 5. Chromic catgut versus Polyglactin-910 for uterine repair The outcomes will include (1) women’s health: pelvic pain; dysmenorrhoea; deep dyspareunia; urinary symptoms; laparoscopy; hysterectomy; tubal/ovarian surgery; abdominal hernias; bowel obstruction; infertility; death. (2) Outcomes of subsequent pregnancies: inter-pregnancy interval; pregnancy outcome; gestation at delivery; mode of delivery; pregnancy complications; surgery during or following delivery. Discussion The results of this follow-up study will have importance for all pregnant women and for health professionals who provide care for pregnant women. Although the results will have been collected in seven countries with limited health care resources (Argentina, Chile, Ghana, India, Kenya, Pakistan, Sudan) any differences in outcomes associated with different surgical techniques are likely to be generalisable throughout the world. Trial registration ISRCTN31089967 PMID:24261693

2013-01-01

154

Zolpidem Use and the Risk of Injury: A Population-Based Follow-Up Study  

PubMed Central

Background While an association between zolpidem use and fracture and road accident was previously proposed, this study aimed to further explore the frequency and risk of a wide spectrum of injuries in subjects prescribed with zolpidem in Taiwan. Methods We identified 77,036 subjects who received Zolpidem treatment between 2005 and 2007. We randomly selected 77,036 comparison subjects who were frequency-matched based-on their demographic profiles. We individually tracked each subject for a 90-day period to identify those who subsequently suffered an injury. Cox proportional hazards regressions were performed to calculate the hazard ratio of injury between the two groups. Results The incidence rate of injury during the 90-day follow-up period for the total subjects was 18.11 (95% CI?=?17.69–18.54) per 100 person-years; this was 24.35 (95% CI?=?23.66–25.05) and 11.86 (95% CI?=?11.39–12.36) for the study and comparison cohort, respectively. After adjusting for demographic variables, the hazard ratio (HR) of injury during the 90-day follow-up period for study subjects was 1.83 (95% CI?=?1.73–1.94) that of comparison subjects. Additionally, compared to comparison subjects, the adjusted HR of injury during the 90-day follow-up period for study subjects who were prescribed Zolpidem for >30 days was as high as 2.17 (95% CI?=?2.05–2.32). The adjusted HR of injury to blood vessels for study subjects was particularly high when compared to comparison subjects (HR?=?6.34; 95% CI?=?1.37–29.38). Conclusions We found that patients prescribed with Zolpidem were at a higher risk for a wide range of injuries. PMID:23826304

Lin, Ching-Chun; Wang, Li-Hsuan; Kang, Jiunn-Horng

2013-01-01

155

Prevention and control of infections in patients with severe congenital neutropenia; a follow up study.  

PubMed

Severe congenital neutropenia is one of primary immunodeficiency disorders that characterized by severe neutropenia and is associated with severe systemic bacterial infections from early infancy. Granulocyte colony stimulating factor (GCSF) is clinically used as a treatment for congenital and acquired neutropenia. The aim of this study was evaluation of GCSF (PD- Grastim) in treatment of these patients. Patients with severe congenital neutropenia referred to Immunology, Asthma and Allergy Research Institute between Jan 2007 and Dec 2010 enrolled the study. Other causes of neutropenia were excluded by serial CBC and bone marrow studies, medical and drug histories and immunological tests. Patients were visited and examined monthly to evaluate their CBC and ANC (absolute neutrophil count), GCSF side effects and dosage adjustment. Cytogenetic studies were being done for all the patients for early detection of progression to AML/MDS. From twenty two patients who enrolled this study, 16 patients regularly evaluated. They were ten males and six females, range in age from 2 to 18 years old. Two patients failed to continue our follow up unfortunately and four patients died due to disease complications. Patients were followed for 24 to 48 months. In a period of 12-24 months before treatment, the mean of hospitalization frequency was 3.1 times and duration was 10 days; while during receiving treatment, they decreased to 0.2 times and 3 days, respectively (p<0.01). Also significant increase in mean ANC was observed during follow up (315/µl before treatment versus 1749/µl after 12 month regular treatment). Bone pain was the most common side effect. There have been no evidences of developing AML/MDS up to present time. Treatment with GCSF significantly reduced the duration and the frequency of hospitalization. Because of plausible progression to AML/MDS, regular follow-up of patients should be continued. PMID:22427476

Salehi, Tahmineh; Fazlollahi, Mohammad Reza; Maddah, Marzieh; Nayebpour, Mohsen; Tabatabaei Yazdi, Mojtaba; Alizadeh, Zahra; Eshghi, Peyman; Chavoshzadeh, Zahra; Movahedi, Masoud; Hamidieh, Amir Ali; Cheraghi, Taher; Pourpak, Zahra; Moin, Mostafa

2012-03-01

156

Undifferentiated spondyloarthritis in a heterogeneous Brazilian population: an eight-year follow-up study.  

PubMed

The aim of the present study was to describe the outcomes of Brazilian patients with undifferentiated spondyloarthritis during an eight-year follow-up period. Patients fulfilling the European Spondyloarthritis (SpA) Study Group Classification Criteria were enrolled. Forty patients were seen at baseline, and 36 participated in the follow-up study. Twenty-three (58%) were female, and there were 24 (60%) African Brazilians enrolled. HLA-B27 was positive in 18 (45%) patients. At disease onset, the first presenting symptoms were pure peripheral manifestations in 26 (72.2%) patients. After the study period, mixed disease (axial + peripheral) predominated occurring in 25 (69.4%) patients. The Assessment of SpA International society (ASAS) classification criteria for axial SpA were fulfilled by 77% of patients, and the ASAS criteria for peripheral SpA were fulfilled by 59% of patients. After 2.5 years, 6 (16.7%) of the 36 patients fulfilled the modified New York Criteria for ankylosing spondylitis and 1 (2.7%) progressed to psoriatic arthritis. A total of 10 (27.8%) patients progressed to definite SpA during the eight-year study period. Buttock pain (p = 0.006, OR 10.55; 95% CI 2.00-65.90) and low-grade radiographic sacroiliitis (p = 0.025, OR = 11.50; 95% CI 1.33-83.39) at baseline were associated with definite SpA. Thus, in this Brazilian cohort, which had a predominance of female African-Brazilian patients, prevalent peripheral onset symptoms were followed by a high frequency of axial manifestations during the follow-up period. Evidence of clinical or radiological sacroiliitis was associated with progression to definite SpA. PMID:23765202

da Cruz Lage, Ricardo; de Souza Bomtempo, Carlos Alexandre; Kakehasi, Adriana Maria; de Carvalho, Marco Antônio Parreiras

2014-07-01

157

A follow-up study of the Preschool Readiness Experimental Screening Scale (the PRESS).  

PubMed

A follow-up study of the Preschool Readiness Experimental Screening Scale (the PRESS) was conducted to determine whether the PRESS is a valid indicator of school readiness. Teacher ratings and Metropolitan Readiness Tests (MRT) scores were obtained at the end of kindergarten for 170 children who had been administered the PRESS before entering kindergarten. When the PRESS scores were compared with the teacher ratings and the MRT scores, the PRESS seemed a valid indicator of school readiness. A modified rating system for interpreting PRESS scores is also proposed. PMID:1116315

Rogers, W B; Rogers, R A

1975-03-01

158

Interaction Association Analysis of Imputed SNPs in Case-Control and Follow-Up Studies.  

PubMed

A new method is described to assess the interactions of imputed SNPs (single nucleotide polymorphisms) in case-control and follow-up studies, properly incorporating SNP imputation uncertainty in the likelihood model. Using simulation studies and analysis of real data obtained from the Framingham study cohort, we compare the performance of this new method to DOSAGE and NAIVE (also known as Best-Guess) methods, developed and commonly used in the context of single SNP and extended to SNP-by-SNP interaction. The results show that only our new method is unbiased under all examined scenarios regarding allele frequencies, imputation uncertainty degree, and interaction effect size. In addition, our method achieves at least as much power as the other two, and exceeds their statistical power in certain follow-up analysis situations. This method is fast enough to perform Genome Wide Interaction Studies (GWIS) with hundreds of thousands of interactions. By performing an exhaustive simulation study let us to provide recommendations for selecting the most appropriated method depending on MAF, interaction effect size, and uncertainty degree. In general, DOSAGE and our proposed method are recommended in most situations being our method more powerful and accurate when uncertainty and effect increase. PMID:25613387

Subirana, Isaac; González, Juan R

2015-03-01

159

A follow-up study of the fate of small asymptomatic deep venous thromboses  

PubMed Central

Background Postoperative asymptomatic deep venous thromboses (ADVT) can give rise to posttthrombotic syndrome (PTS), but there are still many unresolved issues in this context. For example, there is a lack of knowledge regarding the fate of small ADVT following minor orthopedic surgery. This follow-up study evaluates postthrombotic changes and clinical manifestations of PTS in a group of patients with asymptomatic calf vein DVT after surgery for Achilles tendon rupture. Methods Forty-six consecutive patients with distal ADVT were contacted and enrolled in a follow-up consisting of a single visit at the hospital at a mean time of 5 years postoperatively, including clinical examination and scoring, ultrasonography and venous plethysmography. All patients had participated in DVT-screening with colour duplex ultrasound (CDU) 3 and 6 weeks postoperatively and 80% of them were treated with anticoagulation. Results With CDU postthrombotic changes and deep venous reflux were detected at follow-up in more than 50% of the patients, more commonly in somewhat larger calf DVT:s initially affecting more than one vessel. However, only about 10% of the patients had significant venous reflux according to venous plethysmography. No patient had plethysmographic evidence of remaining outflow obstruction, but presence of postthrombotic changes shown with CDU negatively influenced venous outflow capacity measured with plethysmography. A clinical entity of PTS was rarely found and occurred only in two patients (4%) and then classified by Villalta scoring as of mild degree with few clinical signs of disease. Distal ADVT:s detected in the early postoperative period (3 weeks) showed DVT-progression in 75% of the limbs that were still immobilized and without anticoagulation. Conclusions Asymptomatic postoperative distal DVT:s following surgery for Achilles tendon rupture have a good prognosis and a favourable clinical outcome. In our material of 46 patients the general appearance of the clinical entity of PTS at 5 years follow-up was low (<5%). Morphological and functional abnormalities were mainly seen in those patients that initially had somewhat larger distal DVT:s involving more than one deep calf vein segment. PMID:20819203

2010-01-01

160

Testing for Mechanistic Interactions in Long-Term Follow-Up Studies  

PubMed Central

In follow-up studies, interactions are often assessed by including a cross-product term in a (multiplicative) Cox model. However, epidemiologists/clinicians often misinterpret a significant multiplicative interaction as a genuine mechanistic interaction. Though indices specific to mechanistic interactions have been proposed, including the ‘relative excess risk due to interaction’ (RERI) and the ‘peril ratio index of synergy based on multiplicativity’ (PRISM), these indices assume no loss to follow up and no competing death in a study. In this paper, the authors propose a novel ‘mechanistic interaction test’ (MIT) for censored data. Monte-Carlo simulation shows that when the hazard curves are proportional to, non-proportional to, or even crossing over one another, the proposed MIT can maintain reasonably accurate type I error rates for censored data. It has far greater powers than the modified RERI and PRISM tests (modified for censored data scenarios). To test mechanistic interactions in censored data, we recommend using MIT in light of its desirable statistical properties. PMID:25811982

Lin, Jui-Hsiang; Lee, Wen-Chung

2015-01-01

161

Motor development in children at risk of autism: a follow-up study of infant siblings.  

PubMed

Recently, evidence of poor or atypical motor skills in autism spectrum disorder has led some to argue that motor impairment is a core feature of the condition. The current study uses a longitudinal prospective design to assess the development of motor skills of 20 children at increased risk of developing autism spectrum disorder, who were recruited and tested at 9 and 40 months of age, on the basis of having an older sibling diagnosed with the condition. All children completed a range of motor, face processing, IQ and diagnostic assessments at a follow-up visit (aged 5-7 years), providing a detailed profile of development in this group from a number of standardised, parental report and experimental measures. A higher proportion of children than expected demonstrated motor difficulties at the follow-up visit and those highlighted by parental report as having poor motor skills as infants and toddlers were also more likely to have lower face processing scores and elevated autism-related social symptoms at 5-7 years, despite having similar IQ levels. These data lend support to the argument that early motor difficulties may be a risk factor for later motor impairment as well as differences in social communication and cognition, traits that are related to autism spectrum disorder. PMID:24101718

Leonard, Hayley C; Bedford, Rachael; Charman, Tony; Elsabbagh, Mayada; Johnson, Mark H; Hill, Elisabeth L

2014-04-01

162

A follow-up study of the community near the McColl waste disposal site.  

PubMed Central

To assess the effect of interim clean-up measures on the current health of a community, we conducted a follow-up survey of 193 residents living near the McColl waste disposal site and a comparison area located approximately 5 miles from the site. Results from this survey were compared with results from a similar survey conducted 7 years earlier. Odors were detected at least once per week by 32.7% of "high-exposed" respondents in 1988 compared with 68.5% in 1981, but prevalence odds ratios (PORs) comparing symptom reporting between "high-exposed" and comparison-area respondents were greater than that of the 1981 survey for 89% of symptoms. PORs comparing symptom reporting between these two areas were greater than 2.0 for 64% of symptoms assessed in the current survey. Symptoms reported in excess did not represent a single organ system or suggest a mechanism of response. PORs comparing respondents who were very worried about the environment and those reporting no worry were greater than 2.0 for 86% of symptoms. These finding, along with environmental data from the area, suggest that living near the waste disposal site and being very worried about the environment, rather than a toxicologic effect of chemical from the site, explain excess symptom reporting found in this follow-up study. PMID:1954927

Lipscomb, J A; Goldman, L R; Satin, K P; Smith, D F; Vance, W A; Neutra, R R

1991-01-01

163

Freshman withdrawal from college: A positive step toward identity formation? A follow-up study.  

PubMed

Withdrawal from college can be a positive step toward separation from parents and identity formation. Subjects for the present study were all persons who withdrew from a random sample of 432 members of a large freshman class (154 males and 278 females). Subjects were divided into withdrawers versus continuers, with the former group being subdivided into transfers versus nontransfers and withdrew passing versus withdrew failing. All subjects were compared in terms of their responses to a freshman orientation questionnaire and a follow-up interview. The results indicate that both male and female withdrawers as a total group were significantly more dissatisfied with their lives (p<0.05 andp<0.025, respectively) at the time of admission than were continuers Follow-up results also suggest that many of the withdrawers left college and were able to deal with their dissatisfaction in creative ways. Transfers versus nontransfers, as well as withdrew-passing versus withdrew-failing students were also significantly different from each other along several dimensions at the time of admission. The findings have implications for administrators and researchers. PMID:24408758

Timmons, F R

1978-06-01

164

Conservative Treatment Protocol for Keratocystic Odontogenic Tumour: a Follow-up Study of 3 Cases  

PubMed Central

ABSTRACT Background The keratocystic odontogenic tumour is classified as a developmental cyst derived from the enamel organ or from the dental lamina. The treatment of keratocystic odontogenic tumour of the jaw remains controversial. The aim of this study was to report the outcome of our conservative treatment protocol for keratocystic odontogenic tumour. Methods Three patients with different complaints referred to Oral and Maxillofacial Surgery Clinic, Faculty of Dentistry, Selçuk University. Initial biopsy was carried out in all patients and keratocystic odontogenic tumours was diagnosed subsequent to histopathological examination. The patients with keratocystic odontogenic tumours were treated by enucleation followed by open packing. This conservative treatment protocol was selected because of existing young aged patients. The average follow-up duration of the cases was 2 years. Results Out of 3 cases, 2 lesions were present in mandible and 1 lesion in maxilla. There was no evidence of recurrence during follow-up. All the cases were monitored continuously with panoramic radiographs, computed tomography and clinical evaluations. Conclusions This conservative treatment protocol for keratocystic odontogenic tumours, based on enucleation followed by open packing would be a possible choice with a view of offering low recurrence rate and low morbidity rate particularly in young patients. PMID:24421977

Yildirim, Gülsün; Ataoglu, Hanife; Kalayci, Abdullah; Kucuk, Korhan; Esen, Alparslan

2010-01-01

165

Effect of Safe Water on Arsenicosis: A Follow-up Study  

PubMed Central

Background: Arsenic pollution in groundwater, used for drinking purposes, has been envisaged as a problem of global concern. Treatment options for the management symptoms of chronic arsenicosis are limited. Mitigation option available for dealing with the health problem of ground water arsenic contamination rests mainly on supply of arsenic safe water in arsenic-endemic region of Indo-Bangladesh subcontinent. Limited information is available regarding the long-term effect of chronic arsenic toxicity after stoppage of consumption of arsenic-containing water. Objective: The current study was, therefore, done to assess, objectively, the effect of drinking arsenic safe water (<50 ?g/L) on disease manifestation of arsenicosis. Results: Manifestations of various skin lesions and systemic diseases associated with chronic arsenic exposure were ascertained initially by carrying on baseline study on 208 participants in Nadia (Cohort-I, with skin lesion and Cohort-II, without skin lesion) using a scoring system, as developed by us, and compared objectively at the end of each year for 3 year follow-up period. All the participants who had arsenic contaminated drinking water source in their houses were supplied with arsenic removal filters for getting arsenic-free water during the follow-up period. In participants belonging to Cohort-I, the skin score was found to improve significantly at the end of each year, and it was found to be reduced significantly from 2.17 ± 1.09 to 1.23 ± 1.17; P < 0.001 at the end of 3 year's intervention study indicating beneficial effect of safe water on skin lesions. The systemic disease symptom score was also found to improve, but less significantly, at the end of 3 years in both the cohorts. Most important observation during the follow-up study was persistence of severe symptoms of chronic lung disease and severe skin lesion including Bowen's disease in spite of taking arsenic-safe water. Further, death could not be prevented to occur because of lung cancer and severe lung disease. Conclusion: It is, therefore, an urgent need to make arrangement for availability of safe water source among the arsenic-affected people in the district. Many of the people in the affected villages are not aware of contamination of their home tube wells with arsenic. Awareness generation and motivation of the people for testing their drinking water sources for arsenic and environmental interventions like rain water harvesting, ground water recharge, and restricting excessive use of ground water for domestic and agricultural purposes are also important to prevent further exposure of arsenic to these people. PMID:25161968

Majumdar, Kunal K.; Ghose, Aloke; Ghose, Nilima; Biswas, Anirban; Mazumder, D.N. Guha

2014-01-01

166

A follow-up study of children with posterior urethral valve  

PubMed Central

There are not many studies on long term follow up of children following surgery for posterior urethral valve in India. This study was done to assess the growth and renal function of children who had completed five years after surgery for posterior urethral valve at our hospital. Thirty children were included in this study. They were assessed retrospectively for the age and pattern of presentation, time of surgery and outcome. Outcomes measured were stunting, renal failure (GFR, tubular functions) and bladder functions. Fifty per cent of children were symptomatic five years after surgery with enuresis, dribbling, polyuria and recurrent urinary tract infection (UTI). GFR was <60 ml/m/1.73 m2 in 33%. Growth failure, according to the World Health Organization (WHO) definition, was present in one-third of children. A low GFR was associated with growth failure. Poor bladder function evidenced by history of dribbling and significant residual urine was seen in one-third of patients. Residual hydronephrosis was seen in 74%. The most common presenting symptoms of PUV were poor urinary stream followed by recurrent UTI, poor weight gain, renal failure and abdominal mass. Eighty per cent of the study population had undergone surgery in infancy. Five years after surgery, 50% children were symptomatic; 30% had stunting. 33% had a GFR <60 ml/m/1.73 m2 and a significantly greater degree of stunting than those with GFR >60 ml/m/1.73 m2. Sonologically normal kidneys on follow-up were associated with a GFR above 60 ml/m/1.73 m2. Poor bladder function was present in 30% of the children. Univariate analysis showed that statistically significant risk factors for decline in GFR in this study are oligohydramnios and surgery beyond the neonatal period. PMID:20835319

Uthup, S.; Binitha, R.; Geetha, S.; Hema, R.; Kailas, L.

2010-01-01

167

[Study of the follow-up by the general practitioner of the children of separated parents].  

PubMed

In Belgium, on 10 millions of inhabitants, there are more than 31.000 divorces per year and we estimate that 600.000 children are experiencing separation of their parents. The general practitioner (GP) have inevitably the responsability of the medical follow-up of some of these children. The possible professional implications related to these young patients, concerning the GP have never been the subject of a study so far. Consequently the aim of this research was to reveal what is happening in the daily practice of the family practitioner related with the children of separete parents. There were some hypothesis notably about particular working conditions for the GP in connection with possible consequences for these children and possible necessity of special professional attitudes. A qualitative research in focus group was organized with GPs in order to get an interaction between the participants and to go past the concepts supposed before the study. Therefore between September and December 04, 8 focus groups of 10-18 generalist practitioners were set up in Brussels and Mons. Each meeting was axed around couples separated for less than 3 years and children between 0 and 15 years. Finally, 120 GPs discussed about 242 cases of divorces from their practice. The debates totally typed word by word were analysed with assistance of the software QSR N5. The point of view of the GPs is: 1) A divorce affects the working conditions of the general practitioner, for example the parcelling out of the medical follow-up of the child and the fact " of being used" by the family. 2) The conflict between the parents after the separation increases the difficulties for the GP in his daily practice. 3) The parental's separation influences the choice of professional attitudes of the GP, notably vis-a-vis the conflict (for instance to try or not to try the conflict's management). 4) Mainly in conflict situation, parental divorce is a risk for the child; psychological or behavioural disorders, physical health problems, school difficulties, ... 5) Certain professional attitudes of the general practitioner can influence positively the evolution of these children, for example to speak to the two parents. 6) Some professional actions aggravate the situation of the these children, for instance to product certain official written documents (attestations, reports, certificats, ...) in a conflicts context. In conclusion, this study desmonstrates that parental separation affects the medical follow-up of the children by the GPs and that professional attitudes influences positively or negatively the child's evolution. For the first time, some negative consequences of the divorce on children are described in the first line. All this results must be confirmed by quantitative research work. PMID:17091892

Kacenelenbogen, N; Roland, M; Schetgen, M; Dusart, A F

2006-09-01

168

75 FR 70365 - Agency Information Collection (Follow-Up Study of a National Cohort of Gulf War and Gulf Era...  

Federal Register 2010, 2011, 2012, 2013, 2014

...refer to ``OMB Control No. 2900-New...INFORMATION: Titles: Follow-Up Study of a National...10-0488a. OMB Control Number: 2900-New...unexplained multi-system illnesses. VA...currently valid OMB control number. The...Burden: a. Follow-Up Study of a...

2010-11-17

169

66 FR 32361 - Submission for OMB Review; Comment Request; The Jackson Heart Study: Annual Follow-Up With Third...  

Federal Register 2010, 2011, 2012, 2013, 2014

...Review; Comment Request; The Jackson Heart Study: Annual Follow-Up With Third Party...Paperwork Reduction Act of 1995, the National Heart, Lung, and Blood Institute (NHLBI...Proposed Collection Title: The Jackson Heart Study: Annual Follow-up with Third...

2001-06-14

170

Education Longitudinal Study of 2002 (ELS:2002) Third Follow-up Data File Documentation. NCES 2014-364  

ERIC Educational Resources Information Center

This report provides guidance and documentation for users of the combined base-year to third follow-up data of the Education Longitudinal Study of 2002 (ELS:2002). ELS:2002 is sponsored by the National Center for Education Statistics (NCES) of the Institute of Education Sciences, U.S. Department of Education. The base-year and follow-up studies

Ingels, Steven J.; Pratt, Daniel J.; Alexander, Christopher P.; Jewell, Donna M.; Lauff, Erich; Mattox, Tiffany L.; Wilson, David

2014-01-01

171

What Affects Reintegration of Female Drug Users after Prison Release? Results of a European Follow-Up Study  

ERIC Educational Resources Information Center

The main objective of this follow-up study is to explore factors influencing the success or failure of women in reintegrating after their release from prison. Female drug users in five European cities were tracked after being released from prison. Out of 234 female prisoners contacted in prisons, 59 were included in the follow-up study. Structured…

Zurhold, Heike; Moskalewicz, Jacek; Sanclemente, Cristina; Schmied, Gabriele; Shewan, David; Verthein, Uwe

2011-01-01

172

Case study of a spinal epidural capillary hemangioma: a 4-year postoperative follow-up.  

PubMed

Study Design?Case study. Objectives?We report the case of a 58-year-old Caucasian man, who presented with a 4-month history of increasing low back pain and gait difficulty. Objective neurologic examination revealed a severe paraparetic symptomatology without any sphincter involvement. Methods?Spinal magnetic resonance imaging (MRI) showed an extradural mass formation situated dorsally at the level of thoracic vertebrae T2 to T4. Results?A laminectomy was performed with total removal of the mass; histology suggested a highly vascularized lesion with lobular architecture, which seems a very rare case, compatible with a capillary hemangioma. Conclusions?A careful follow-up for the next 4 years, including control MRIs every postoperative year, showed a very good neurologic condition of the patient and no recurrence on imaging findings. PMID:24494182

Seferi, Arsen; Alimehmeti, Ridvan; Vyshka, Gentian; Bushati, Teona; Petrela, Mentor

2014-02-01

173

Bone destruction, upward migration, and medialisation of rheumatoid shoulder: a 15 year follow up study  

Microsoft Academic Search

OBJECTIVETo evaluate bone destruction, upward migration, and medialisation of the glenohumeral (GH) joint in a cohort of 74 patients with seropositive and erosive rheumatoid arthritis followed up prospectively.METHODSAt the 15 year follow up 148 shoulders were radiographed by a standard method. Bone destruction in the GH joint was examined from the radiographs by four methods, of which three measured the

J T Lehtinen; E A Belt; M J Kauppi; K Kaarela; P P Kuusela; H J Kautiainen; M U K Lehto

2001-01-01

174

NHEXAS PHASE I REGION 5 STUDY--FOLLOW-UP QUESTIONNAIRE DATA (MONITORING PERIOD 1)  

EPA Science Inventory

This data set includes responses for 249 follow-up questionnaires collected during the first week-long monitoring period. The Follow-up Questionnaire was used to provide information on relatively infrequent (e.g., less than daily) activities during the sampling period to explain ...

175

NHEXAS PHASE I ARIZONA STUDY--FOOD FOLLOW-UP QUESTIONNAIRE DATA  

EPA Science Inventory

The Food Follow-up Questionnaire data set provides information on the eating patterns and the food identification and preparation methods that occurred during the period the food sample was taken. The information is for 179 Food Follow-up Questionnaires for 179 households. In t...

176

U.S.-MEXICO BORDER PROGRAM ARIZONA BORDER STUDY--FOOD FOLLOW-UP QUESTIONNAIRE DATA  

EPA Science Inventory

The Food Follow-up Questionnaire data set provides information on the eating patterns and the food identification and preparation methods that occurred during the period the food sample was taken. The information is for 86 Food Follow-up Questionnaires for 86 households. In the...

177

System Characteristic Opinion Study (SCOS-DELPHI). Project FOLLOW-UP.  

ERIC Educational Resources Information Center

Using the Delphi technique, the staff of Project FOLLOW-UP surveyed community college educators in Texas to determine desirable characteristics and uniformity of terminology and definitions for a proposed statewide student follow-up management information system for Texas community colleges. Of 234 individuals invited to become Delphi panel…

Cox, Jeannene

178

Risky driving and recorded driving offences: a 24-year follow-up study.  

PubMed

Permanent individual differences in driver behavior and accident risk have long been under active debate. Cognitive and personality factors have correlated with risky driving indicators in cross-sectional studies, and prospective cohort studies are now increasingly revealing early antecedents of risky behavior and injury mortality in adult age, with connections to stable personality traits. However, long-term stability in driver behavior or accident involvement has not been documented in a general driver population.This study reports 24-year follow-up data from a study that compared the recorded offenses between 134 drivers stopped by the police because of sustained risky driving and 121 control drivers stopped at the same locations at the same time in 1987 (Rajalin, 1994. Accid. Anal. Prev., 26, 555-562). Data were compiled from national driver records and accident statistics for the same drivers again 24 years later, and their yearly mileage and speed behavior was requested in a mail survey. The results showed that the two groups of drivers sampled on one trip a quarter of a century ago still differ from each other. The offenders still have more entries in their driver record, also when adjusted for age and mileage (OR=1.59, CI=1.03-2.46), they still report in the survey that they drive faster and overtake other cars more often. The results show that individual differences in driver behavior persist for decades, perhaps for life. However, in this on-road sample, the effect seems to be moderated by occupation which also presumably explains the lower mortality among the offenders during this 24-year follow-up. PMID:25171522

Summala, Heikki; Rajalin, Sirpa; Radun, Igor

2014-12-01

179

Asian-Specific total knee system: 5-14 year follow-up study  

PubMed Central

Background Knee size and body size differ in Asians compared with Caucasians. Nevertheless, many total knee arthroplasty (TKA) prostheses used worldwide are made for Western Caucasian subjects. As a result, an Asian's knee might not fit these prostheses. We studied the Flexible Nichidai Knee (FNK) system, a new model of TKA for Asian patients. The purpose of this report is to investigate the outcomes of this prosthesis retrospectively. Methods We investigated 1055 primary TKAs in 595 patients who underwent FNK for osteoarthritis (OA) in Japan and were followed for > 5 years. The knee score and function score were used for clinical evaluation. We examined the range of motion (ROM) preoperatively and at final follow-up and radiographic assessments. In addition, postoperative complications were investigated. A survivorship analysis was also conducted using two endpoints: revision for any reason and aseptic failure. Results 890 knees in 502 patients were available for study (follow-up rate of 96.0%). The mean follow-up term was 8.3 years (range, 5.0-14.1 years). The knee and function score significantly improved from 41.3 to 90.3 and from 39.1 to 76.2 points, respectively (p < 0.001). The mean ROM in FNK posterior cruciate retaining (CR) type and FNK posterior-stabilized (PS) type ameliorated significantly from 107.8° and 95.6° to 110.7° and 110.4°, respectively (p < 0.01). Ten knees underwent revision surgery (infection in 3 cases, instability in 2, loosening in 2, and non-union of femoral supracondylar fracture, severe pain, and recurrent hemarthrosis in 1 each). The survivorship rate was 99.4% (95% CI, 99.0-99.8) at 5 years (n = 952 patients at risk) and 96.2% (95% CI, 91.9-100) at 12.5 years (n = 49 patients at risk). Conclusion The FNK prosthesis for Asians achieved excellent mid- to long-term survivorship and clinical results. PMID:22046953

2011-01-01

180

Cervical spine involvement in patients with juvenile idiopathic arthritis - MRI follow-up study  

PubMed Central

Background To describe MRI and clinical findings in patients with juvenile idiopathic arthritis with cervical spine involvement at onset and follow-up under therapy. Methods 13 patients with signs of cervical spine involvement in juvenile idiopathic arthritis with a median disease duration of 1.7 years were included in the study. Clinical records and MR images were retrospectively analyzed according to symptoms and findings concerning the cervical spine. Results At the onset of cervical spine involvement all patients showed limited range of motion, whereas only 5 of them complained of pain. In MR images joint hyperintensity, contrast enhancement, malalignment, ankylosis, erosion and narrowing of the spinal canal at cranio-cervical junction were found at 28, 32, 15, 2, 2 and 3 sites in 12 (93%), 13 (100%), 8 (62%), 2 (15%), 2 and 3 (20%) patients respectively. 3 of the 5 patients with pain (60%) showed ankylosis, erosions or narrowing of the spinal canal at cranio-cervical junction on MRI. At follow-up - after a median disease duration of cervical spine arthritis of 2.1 years and a variable duration of treatment with methotrexate (all patients) and biological agents (12 patients) - joint hyperintensity, enhancement and malalignment decreased to 15, 19 and 6 sites in 10 (77%), 11 (85%) and 3 (20%) patients respectively whereas ankylosis, erosion and narrowing of the spinal canal at cranio-cervical junction increased to 7, 6 and 4 sites in 3 (20%), 4 (31%) and 4 patients respectively. Pain was no longer reported, but 9 of 13 (69%) patients still had a limited range of motion with 6 of them (46%) showing skeletal changes on MRI. Conclusions This first MRI based follow-up study shows that cervical spine arthritis can follow a severe disease course in juvenile arthritis. While malalignments and inflammation sites decreased osseous changes with erosions, ankylosis, and narrowing of the spinal canal increased under treatment despite only minor subjective complaints. Therefore close MRI monitoring of these patients appears to be reasonable. PMID:24593886

2014-01-01

181

Disaster exposure as a risk factor for mental health problems, eighteen months, four and ten years post-disaster – a longitudinal study  

PubMed Central

Background Disaster experiences have been associated with higher prevalence rates of (mental) health problems. The objective of this study was to examine the independent relation between a series of single disaster experiences versus the independent predictive value of a accumulation of disaster experiences, i.e. a sum score of experiences and symptoms of distress and post-traumatic stress disorder (PTSD). Methods Survivors of a fireworks disaster participated in a longitudinal study and completed a questionnaire three weeks (wave 1), eighteen months (wave 2) and four years post-disaster (wave 3). Ten years post-disaster (wave 4) the respondents consisted of native Dutch survivors only. Main outcome measures were general distress and symptoms of PTSD. Results Degree of disaster exposure (sum score) and some disaster-related experiences (such as house destroyed, injured, confusion) were related to distress at waves 2 and 3. This relation was mediated by distress at an earlier point in time. None of the individual disaster-related experiences was independently related to symptoms of distress. The association between the degree of disaster exposure and symptoms of PTSD at waves 2 and 3 was still statistically significant after controlling for symptoms of distress and PTSD at earlier point in time. The variable ‘house destroyed’ was the only factor that was independently related to symptoms of PTSD at wave 2. Ten years after the disaster, disaster exposure was mediated by symptoms of PTSD at waves 2 and 3. Disaster exposure was not independently related to symptoms of PTSD ten years post-disaster. Conclusions Until 4 years after the disaster, degree of exposure (a sum score) was a risk factor for PTSD symptoms while none of the individual disaster experiences could be identified as an independent risk factor. Ten years post-disaster, disaster exposure was no longer an independent risk factor for symptoms of PTSD. Since symptoms of PTSD and distress at earlier waves perpetuate the symptoms at later waves, health care workers should aim their resources at those who still have symptoms after one and a half year post-disaster, to prevent health problems at medium and long-term. PMID:22989093

2012-01-01

182

Comparison of hospice use by European americans, african americans, and latinos: a follow-up study.  

PubMed

This study investigated the rate of hospice use by Latinos and African Americans relative to their prevalence in the general population between 2004 and 2010 as a follow-up to a previous investigation. Archival data (N = 2625) were collected on patients' race/ethnicity, gender, marital status, length of stay in hospice, and reason for discharge. In contrast to previous findings, African Americans were more likely to utilize hospice services, but Latinos were less likely to use hospice services compared to the other groups. There were no differences among the racial/ethnic groups in terms of length of stay or disposition at termination. Strengthening efforts to reach a larger racial/ethnic representation in hospice programs may increase the rate of hospice use by some racial/ethnic groups but not others. PMID:24219885

Colón, Merydawilda; Lyke, Jennifer

2015-03-01

183

Hand-arm vibration syndrome among travertine workers: a follow up study.  

PubMed Central

In a six year follow up study of the handarm vibration syndrome, 62 stoneworkers operating hand held vibrating tools in 10 travertine quarries and mills were first investigated in 1985 and then in 1991. The frequency weighted acceleration of vibration from the rock drills and stone hammers used by the travertine workers exceeded 20 m/s2, indicating a hazardous work activity according to the proposal of the EC directive for physical agents. A clinical examination and a cold provocation test were repeated with the same procedures as those adopted at the time of the first survey. The stoneworkers were divided into groups according to current work state: active stoneworkers who continued to use powered tools during the follow up (n = 21, median exposure time 22 years), and ex-stoneworkers with retirement vibration free intervals of three years (n = 22, median exposure time 27.5 years) and of six years (n = 19, median exposure time 20 years). In the group of active stoneworkers, a 38% onset a new cases of vibration-induced white finger (VWF) was found during the follow up (p < 0.01). Among the retired stoneworkers affected with VWF (n = 24), one recovered from VWF, one showed improvement, 20 remained stationary, and two deteriorated. The ex-stoneworkers experienced no significant change in sensorineural disturbances and a decrease in musculoskeletal symptoms of the upper limbs. At the cold provocation test, the currently active stoneworkers with VWF showed, on a group basis, a delayed finger rewarming time between the two examinations (p = 0.002). An abnormal response to cold provocation persisted in the fingers of the ex-stoneworkers with VWF, even in those reporting subjective improvement. These findings indicate a tendency towards the irreversibility of sensorineural and VWF symptoms in a group of ex-stoneworkers with prolonged exposure to high vibration levels in the past. The increased occurrence of VWF in the active stone workers after a few extra years of vibrating tool usage argues for an urgent implementation of preventive measures in the stone industry. PMID:8044226

Bovenzi, M; Franzinelli, A; Scattoni, L; Vannuccini, L

1994-01-01

184

Prevalence of celiac disease in Germany: A prospective follow-up study  

PubMed Central

AIM: To determine the prevalence of celiac disease in a randomly selected population sample. METHODS: A total of 2157 subjects (1036 males; 1121 females) participating in a population-based cross-sectional study underwent laboratory testing for tissue transglutaminase and antibodies to immunoglobulin A, endomysium and antigliadin. In a second step, all subjects who had been examined serologically were surveyed using a questionnaire that included questions specific to celiac disease. Subjects with positive antibody titers and those with histories positive for celiac disease then underwent biopsy. At the first follow up, antibody titers were again determined in these subjects and subjects were questioned regarding symptoms specific for celiac disease and disorders associated with celiac disease. The second follow up consisted of a telephone interview with subjects positive for celiac disease. RESULTS: Antibody tests consistent with celiac disease were reported in eight subjects, corresponding to an overall prevalence of 1:270 (8/2157). The prevalence among women was 1:224 and 1:518 in men. Classical symptoms were observed in 62.5% of subjects. Atypical celiac disease was present in 25.0%, and transient celiac disease in 12.5%. False-negative test results were returned in three subjects. This yields a sensitivity and specificity of 62.5% and 50.0%, respectively, for tissue transglutaminase immunoglobulin-A antibody; of 62.5% and 71.4% respectively, for endomysium antibody; and of 62.5% and 71.4%, respectively, for antigliadin antibody. CONCLUSION: The prevalence rate in our collective lies within the middle tertile of comparable studies in Europe. The use of a single antibody test for screening purposes must be called into question. PMID:23674868

Kratzer, Wolfgang; Kibele, Monika; Akinli, Atilla; Porzner, Marc; Boehm, Bernhard O; Koenig, Wolfgang; Oeztuerk, Suemeyra; Mason, Richard A; Mao, Ren; Haenle, Mark H

2013-01-01

185

Relationships in couples treated with sperm donation - a national prospective follow-up study  

PubMed Central

Background Long-term follow-up on relationship quality in couples who use sperm donation is scarce. Therefore, this study aimed to analyse changes over time in satisfaction with relationship in heterosexual couples who were scheduled for treatment with sperm donation and IVF couples treated with their own gametes and to compare the two groups undergoing different treatment for infertility. Method A prospective follow-up study in which data were collected twice on two groups; couples receiving sperm donation and IVF couples using their own gametes. The ENRICH instrument was used to gain information about the individuals’ subjective experience of their relationship at the time of acceptance for treatment and again 2–5 years later. Results At the time of acceptance for treatment the men and women in the two groups assessed their relationships as being very solid on all dimensions and that there were no differences between the two groups. At the second assessment there was a decline in the satisfaction scores on the dimensions “Children and parenting” and “Egalitarian”, while an increase in scores was observed on “Conception of life” and “Conflict resolution” both for men and woman and also for the two groups. For the couples that had a successful treatment and gave birth to a child/children there was a decrease in satisfaction of the relation in the sperm donation group as well as in the group of couples having IVF with own gametes. Conclusion In conclusion, the overall quality of relationship is stable in couples receiving donated sperm and does not differ from couples undergoing IVF-treatment with own gametes. PMID:25100133

2014-01-01

186

Wilson's disease in southern Brazil: a 40-year follow-up study  

PubMed Central

BACKGROUND: Long-term data on the clinical follow-up and the treatment effectiveness of Wilson's disease are limited because of the low disease frequency. This study evaluated a retrospective cohort of Wilson's disease patients from southern Brazil during a 40-year follow-up period. METHODS: Thirty-six Wilson's disease patients, diagnosed from 1971 to 2010, were retrospectively evaluated according to their clinical presentation, epidemiological and social features, response to therapy and outcome. RESULTS: Examining the patients' continental origins showed that 74.5% had a European ancestor. The mean age at the initial symptom presentation was 23.3 ± 9.3 years, with a delay of 27.5 ± 41.9 months until definitive diagnosis. At presentation, hepatic symptoms were predominant (38.9%), followed by mixed symptoms (hepatic and neuropsychiatric) (30.6%) and neuropsychiatric symptoms (25%). Kayser-Fleischer rings were identified in 55.6% of patients, with a higher frequency among those patients with neuropsychiatric symptoms (77.8%). Eighteen patients developed neuropsychiatric features, most commonly cerebellar syndrome. Neuroradiological imaging abnormalities were observed in 72.2% of these patients. Chronic liver disease was detected in 68% of the patients with hepatic symptoms. 94.2% of all the patients were treated with D-penicillamine for a mean time of 129.9 ± 108.3 months. Other treatments included zinc salts, combined therapy and liver transplantation. After initiating therapy, 78.8% of the patients had a stable or improved outcome, and the overall survival rate was 90.1%. CONCLUSION: This study is the first retrospective description of a population of Wilson's disease patients of mainly European continental origin who live in southern Brazil. Wilson's disease is treatable if correctly diagnosed, and an adequate quality of life can be achieved, resulting in a long overall survival. PMID:21552664

de Bem, Ricardo Schmitt; Muzzillo, Dominique Araujo; Deguti, Marta Mitiko; Barbosa, Egberto Reis; Werneck, Lineu César; Teive, Hélio Afonso Ghizoni

2011-01-01

187

Hong Kong Chinese school children with elevated urine melamine levels: A prospective follow up study  

PubMed Central

Background In 2008, the outbreak of kidney stones in children fed by melamine-tainted milk products in Mainland China has caused major public concern of food safety. We identified Hong Kong school children with elevated urine melamine level from a community-based school survey in 2007-08 and reviewed their clinical status in 2009. Methods In 2007-08, 2119 school children participated in a primary and secondary school survey in Hong Kong using a cluster sampling method. Urine aliquots from 502 subjects were assayed for melamine level. High urine melamine level was defined as urine melamine/creatinine ratio >7.1 ?g/mmol. Subjects with high urine melamine level were invited for clinical evaluation in 2009 including urinalysis and ultrasound imaging of the urinary system. Results The age range of this subcohort was 6 - 20 years with 67% girls (335 female and 167 male subjects). The spot urine melamine/creatinine ratio of the 502 urine aliquots ranged from undetectable to 1467 ?g/mmol (median 0.8 ?g/mmol). Of these, 213 subjects had undetectable level (42%). We invited 47 (9%) subjects with high urine melamine level for re-evaluation and one subject declined. The median duration of follow-up was 23.5 months (interquartile range: 19.8 - 30.6 months). None of the 46 subjects (28% boys, mean age 13.9 ± 2.9 years) had any abnormality detected on ultrasound study of the urinary system. All subjects had stable renal function with a median urine albumin-creatinine ratio of 0.70 mg/mmol (interquartile range: 0.00 - 2.55 mg/mmol). Conclusions Hong Kong Chinese school children with high urine melamine levels appeared to have benign clinical course in the short term although a long term follow-up study is advisable in those with persistently high urine melamine level. PMID:21599964

2011-01-01

188

The International Immune Tolerance Induction Study and its follow-up study on Japanese hemophilia A patients with inhibitors.  

PubMed

The International Immune Tolerance Induction (I-ITI) Study in hemophilia A patients with inhibitors included 16 Japanese patients among a total of 115 test subjects. The results within this group of Japanese patients were 11 cases of I-ITI off-study, three cases of I-ITI on-study, and two cases of tolerance on prophylaxis. There was no significant difference in success rate between the low-dose and high-dose groups (Study I). Successively, independent follow-up survey in Japan was conducted in 14 cases, with consent (Study II). Ten cases were off-study at the end of the I-ITI Study. Of these 10 cases, seven of seven successful cases remained clinical successes at the end of the follow-up study, one partial success became a full success while a second relapsed, and one failure was subsequently evaluated as a partial success. Four cases that were on-study at the end of I-ITI Study were classified as three successes and one failure at the end of the follow-up study. As a result, the status at the end of follow-up study was: 11 ITI successes (78.6 %); one partial success; one failure; and one relapse. Thus, the ITI follow-up study was helpful in providing a long-term prognostic determination of inhibitors. PMID:25690486

Yoshioka, Akira; Ishii, Eizaburo; Ueno, Tamaki; Usami, Ikuya; Kobayashi, Masao; Kobayashi, Ryoji; Sotomatsu, Manabu; Shirahata, Akira; Suzuki, Takashi; Taki, Masashi; Ishida, Yasushi; Matsushita, Tadashi; Shima, Midori; Nogami, Keiji; Sakai, Michio; Kigasawa, Hisato; Fukutake, Katsuyuki

2015-04-01

189

Childhood Predictors of Male Criminality: A Prospective Population-Based Follow-up Study from Age 8 to Late Adolescence  

ERIC Educational Resources Information Center

Objective: To study childhood predictors for late adolescence criminality. Method: The follow-up sample included 2,713 Finnish boys born in 1981. Information about the 8-year-old boys' problem behavior was obtained from parents, teachers, and the children themselves. The follow-up information about criminal offenses was based on the national…

Sourander, Andre; Elonheimo, Henrik; Niemela, Solja; Nuutila, Ari-Matti; Helenius, Hans; Sillanmaki, Lauri; Piha, Jorma; Tamminen, Tuula; Kumpulainen, Kirsti; Moilanen, Irma; Almqvist, Frederik

2006-01-01

190

Does follow-up duration influence the ultrasound and DXA prediction of hip fracture? The EPIDOS prospective study  

Microsoft Academic Search

While the potential of quantitative ultrasound (QUS) in the management of osteoporosis has been accepted, its interaction with follow-up time has never been investigated. The aim of our study is to prospectively evaluate the influence of follow-up time on the prediction of hip fracture by ultrasound parameters in the elderly as compared to bone mineral density (BMD) and to establish

D Hans; A. M Schott; F Duboeuf; C Durosier; P. J Meunier

2004-01-01

191

A model for planning optimal follow-up for outpatients on warfarin anticoagulation. Warfarin Optimal Outpatient Follow-up Study Group.  

PubMed

Patients taking warfarin for long-term anticoagulation require frequent clinic visits to monitor the prothrombin time ratio (PTR), a measure of blood clotting. A dynamic stochastic model using nonlinear optimization was developed to select follow-up visit intervals that minimize the overall costs of patient care. Assuming that fluctuations in a patient's PTR behave as a random diffusion process, future PTR fluctuations are unknown, except as revealed by past PTRs. To determine the incidence and costs of complications in relation to PTR, the authors reviewed the charts of 216 patients who had 719 patient-years of follow-up with 695 trivial, significant, life-threatening, or fatal complications. They modeled the relationship between costs of complications and deviation of the PTR from the therapeutic target as a fourth-order convex polynomial. The model is used to compute the interval to the next follow-up visit to minimize accumulated potential costs. Variables in the optimization are the cost of a monitoring visit and the expected costs of complications. The latter are derived from the current PTR, the variability of the patient's past PTR values, the number of past PTRs available, and the target PTR for the patient. No attempt is made to predict the level of the next PTR or suggest adjustments in the warfarin dose. Shorter follow-up is recommended for patients who have histories of large fluctuations in past PTRs and for patients with few prior PTR determinations. As visits accumulate, the patient's degree of variability can be estimated more accurately and visit intervals adjusted accordingly. The scheduling method balances costs to the health care system of monitoring each patient against the expected costs of complications. This approach has the potential to reduce the number of monitoring visits necessary for safe management of anticoagulated patients with stable PTRs and to improve control among unstable patients. PMID:1573980

Kent, D L; Vermes, D; McDonell, M; Henikoff, J; Fihn, S D

1992-01-01

192

Continuous Commissioning Results Verification and Follow-up For an Institutional Building: A Case Study  

E-print Network

, or controls by-pass or override, the follow up activities and possible new CC measures will adapt the systems to these changes. This paper presents the verification and follow-up efforts, which identified control problems in air handling units and lab... was able to optimize control scheme-reset schedules on the air-side (AHU) and water-side (pump) systems in the building and improve operations for the terminal boxes by implementing CC measures during initial CC implementation and follow-up...

Chen, H.; Deng, S.; Bruner, H. L.; Claridge, D. E.; Turner, W. D.

2002-01-01

193

The Study Guides and Strategies Website (www.studygs.net): Ten-Year Update and Current Applications  

ERIC Educational Resources Information Center

Over five years ago the author began his "TechTrends" column, then titled "E-Learning by Design," with a self interview. In that first column he interviewed himself on how he came to develop the Study Guides and Strategies (SGS) Website www.studygs.net. This educational public service and resource now contains 120 topics (200 English webpages) in…

Landsberger, Joe

2006-01-01

194

Personality Effects on Romantic Relationship Quality through Friendship Quality: A Ten-Year Longitudinal Study in Youths  

PubMed Central

This study examined whether individuals with different personality types (i.e., overcontrollers, undercontrollers, resilients) had different friendship quality development throughout adolescence. It also investigated whether personality types were indirectly related to romantic relationship quality in young adulthood, via friendship quality development in adolescence. The study employed six waves of longitudinal questionnaire data from Dutch youths who had a romantic relationship when they were young adults. Two age cohorts were followed, from 12 to 21 years and from 16 to 25 years, respectively. Findings showed that resilients reported higher mean levels of friendship quality during adolescence (i.e., more support from, less negative interaction with and less dominance from their best friend) than both overcontrollers and undercontrollers. Through the mean levels of friendship quality throughout adolescence, resilients indirectly experienced higher romantic relationship quality during young adulthood than both overcontrollers and undercontrollers. Thus, results provide support for a developmental model in which adolescent friendship quality is a mechanism linking personality types with young adulthood romantic relationship quality. PMID:25232964

Yu, Rongqin; Branje, Susan; Keijsers, Loes; Meeus, Wim H. J.

2014-01-01

195

Recovery Potential of a Western Lowland Gorilla Population following a Major Ebola Outbreak: Results from a Ten Year Study  

PubMed Central

Investigating the recovery capacity of wildlife populations following demographic crashes is of great interest to ecologists and conservationists. Opportunities to study these aspects are rare due to the difficulty of monitoring populations both before and after a demographic crash. Ebola outbreaks in central Africa have killed up to 95% of the individuals in affected western lowland gorilla (Gorilla gorilla gorilla) populations. Assessing whether and how fast affected populations recover is essential for the conservation of this critically endangered taxon. The gorilla population visiting Lokoué forest clearing, Odzala-Kokoua National Park, Republic of the Congo, has been monitored before, two years after and six years after Ebola affected it in 2004. This allowed us to describe Ebola's short-term and long-term impacts on the structure of the population. The size of the population, which included around 380 gorillas before the Ebola outbreak, dropped to less than 40 individuals after the outbreak. It then remained stable for six years after the outbreak. However, the demographic structure of this small population has significantly changed. Although several solitary males have disappeared, the immigration of adult females, the formation of new breeding groups, and several birth events suggest that the population is showing potential to recover. During the outbreak, surviving adult and subadult females joined old solitary silverbacks. Those females were subsequently observed joining young silverbacks, forming new breeding groups where they later gave birth. Interestingly, some females were observed joining silverbacks that were unlikely to have sired their infant, but no infanticide was observed. The consequences of the Ebola outbreak on the population structure were different two years and six years after the outbreak. Therefore, our results could be used as demographic indicators to detect and date outbreaks that have happened in other, non-monitored gorilla populations. PMID:22649511

Gatti, Sylvain; Levréro, Florence; Bigot, Elodie; Caillaud, Damien; Pierre, Jean-Sébastien; Ménard, Nelly

2012-01-01

196

Return to work following unintentional injury: a prospective follow-up study  

PubMed Central

Objective The aim of this study was to predict time off work following unintentional injuries due to accidents leading to hospital admission. Design Prospective 6-month follow-up study. Setting Department of Trauma Surgery of a University Hospital. Participants Consecutively recruited victims of unintentional injuries (n=221) hospitalised for a minimum of 32?h including two consecutive nights. All the participants were aged 18–65?years and were able to participate in an assessment within 30?days of the accident. Main outcome measures Interview-assessed number of days off work during the 6?months immediately following the accident. Results The patients’ subjective appraisals of (1) accident severity and (2) their ability to cope with the resulting injury and its job-related consequences predicted time off work following the accident beyond the impact of the objective severity of their injury and the type of accident involved. Conclusions The patients’ subjective appraisals of the accident severity and of their ability to cope with its consequences are highly relevant for return to work after accidents. Extending the findings from previous studies on severely injured and otherwise preselected accident victims, this seems to apply to the whole spectrum of patients hospitalised with unintentional injuries. PMID:24327361

Hepp, Urs; Schnyder, Ulrich; Hepp-Beg, Sofia; Friedrich-Perez, Josefina; Stulz, Niklaus; Moergeli, Hanspeter

2013-01-01

197

Relationships in oocyte recipient couples – a Swedish national prospective follow-up study  

PubMed Central

Background The long-term effect of treatment with donated oocytes on women’s and men’s perception of their relationship has been little studied. Thus the aim of this study was to analyse satisfaction with relationships in couples at the time of acceptance for treatment and 2–5 years after treatment with donated gametes and to compare them with IVF couples treated with their own gametes. Method A prospective follow-up study in which data were collected twice on two groups; cohabitating couples receiving oocyte donation and cohabitating IVF couples using their own gametes. A standardised instrument, the ENRICH inventory, was used to gain information about the couples’ subjective experience of their relationships. Results At acceptance for treatment the couples in the two groups assessed their relationships as being very solid on all dimensions and that the women receiving treatment with oocyte showed a higher satisfaction compared to women treated with own gametes. For couples that did have a child, the group of women who had been through the oocyte donating program reported a better quality of their relationship than women in the control group. There were no significant differences in perceived relationship quality between men in the different groups, whether they had a child or not. Conclusions From a long-term perspective couples using oocyte donation treatment have a balanced and solid view of their relationship and treatment, having children or not after treatment did not affect the nature of the relationships. PMID:24885541

2014-01-01

198

Investigations on health hazards of chimney sweeps in Germany: results of a follow-up study.  

PubMed

Within the framework of a longitudinal study, 127 chimney sweeps from the area of Upper and Middle Franconia (Bavaria, Germany), who had participated in a first medical check-up in 1974, were offered follow-up examinations in 1990. Eighty-one subjects participated in these examinations; in addition individual occupational case histories and medical case histories were obtained for a further 15 and 35 chimney sweeps, respectively. Five test subjects had died before the evaluation deadline (August 15, 1990). The causes of death were a non-Hodgkin's lymphoma, a bladder carcinoma, pulmonary metastases with unknown primary tumour, a suicide and an acute myocardial infarction. Conspicuous results were carcinoma of the oesophagus in one case and leucoplakia of the mucous membranes in the mouth and pharyngeal region in three cases; furthermore one chimney sweep had two haemorrhagic lumps on his vocal cords. Taking into account important non-occupational hazards (alcohol and nicotine abuse) as possible causes of these changes and the lack of relevant occupational exposure to products of incineration over a number of years, none of these cases nor any of the other ascertained results could be considered likely to be causally related to occupational activities. Due to the small number of cases, an epidemiological risk evaluation did not seem useful. Comparison with the results of other chimney sweep studies published in the international literature is not helpful due to the differences in study design, the varying case frequencies, and the different conditions of exposure. PMID:1399014

Letzel, S; Weber, A; Schaller, K H; Angerer, J; Iro, H; Waitz, G; Knorr-Held, F; Weltle, D; Lehnert, G

1992-01-01

199

Involvement in bullying and suicidal ideation in middle adolescence: a 2-year follow-up study.  

PubMed

The objective of the study was to ascertain whether involvement in bullying increases the risk for subsequent suicidal ideation. A total of 2,070 Finnish girls and boys aged 15 were surveyed in the ninth grade (age 15) in schools, and followed up 2 years later in the Adolescent Mental Health Cohort Study. Involvement in bullying was elicited at age 15 by two questions focusing on being a bully and being a victim of bullying. Suicidal ideation was elicited by one item of the short Beck Depression Inventory at age 17. Baseline depressive symptoms and externalizing symptoms, age and sex were controlled for. Statistical analyses were carried out using cross-tabulations with Chi-square/Fisher's exact test and logistic regression. Suicidal ideation at age 17 was 3-4 times more prevalent among those who had been involved in bullying at age 15 than among those not involved. Suicidal ideation at age 17 was most prevalent among former victims of bullying. Being a victim of bullying at age 15 continued to predict subsequent suicidal ideation when depressive and externalizing symptoms were controlled for. Being a bully at age 15 also persisted as borderline significantly predictive of suicidal ideation when baseline symptoms were controlled for. Findings indicate adolescent victims and perpetrators of bullying alike are at long-term risk for suicidal ideation. PMID:23053774

Heikkilä, Hanna-Kaisa; Väänänen, Juha; Helminen, Mika; Fröjd, Sari; Marttunen, Mauri; Kaltiala-Heino, Riittakerttu

2013-02-01

200

Radioactive iodine therapy and breast cancer. A follow-up study of hyperthyroid women  

SciTech Connect

A follow-up study of 1762 hyperthyroid women who were treated at the Massachusetts General Hospital Thyroid Unit between 1946 and 1964 was conducted. The average length of follow-up was 17.2 years. A 1978 mailing address or a death certificate was located for 92% of the women, and 88% of 1058 living patients responded to a mail questionnaire. The standardized mortality ratio (SMR) for all causes of death was 1.3 (95% confidence interval (CI) 1.2-1.4). The standardized mortality ratios for all malignant neoplasms and for breast cancer were 0.9 (95% CI 0.7-1.1) and 1.3 (95% CI 0.8-1.9), respectively. More deaths than expected were observed from endocrine and metabolic diseases (SMR = 1.8, 95% CI 1.2-2.7), circulatory system diseases (SMR = 1.4, 95% CI 1.3-1.6), and respiratory system diseases (SMR = 1.9, 95% CI 1.3-2.6). The standardized incidence ratios (SIR) for all malignant neoplasms and for breast cancer were 0.9 (95% CI 0.8-1.1) and 1.2 (95% CI 0.9-1.5), respectively. A nonsignificant excess breast cancer risk was observed 10 years after the onset of thyroid symptoms and was present at the end of 30 years of observation. A statistically significant excess number of pancreatic cancer cases (SIR = 2.0, 95% CI 1.0-3.7) and a nonsignificant excess of brain cancer cases (SIR = 2.3, 95% CI 0.7-5.3) were observed. Eighty per cent of the women were treated with radioactive iodine. When age at treatment and year of treatment were controlled, women who were ever treated with radioactive iodine had a standardized rate ratio for breast cancer of 1.9 (95% CI 0.9-4.1), compared with those who were never treated with radioactive iodine. Women who developed hypothyroidism as a result of their treatment for hyperthyroidism did not have an increased risk of developing breast cancer (SIR = 1.1, 95% CI 0.8-1.6).

Goldman, M.B.; Maloof, F.; Monson, R.R.; Aschengrau, A.; Cooper, D.S.; Ridgway, E.C.

1988-05-01

201

Treatment of alcoholism in Kuwait: a prospective follow-up study.  

PubMed

The outcome of routine drug-supportive psychotherapy treatment of 100 patients with alcohol-related problem in Kuwait's only psychiatric hospital was evaluated in four 6 month's intervals. Patients were assessed on 9 post-treatment questions reflecting improvement or deterioration. Correlation of follow-up changes to pre-treatment data shows that non-Kuwaitis do better than Kuwaitis in resuming employment and social reintegration. Patients on chronic benzodiazepine prescription were less likely to become abstinent, had poor social re-integration and more re-admissions. Good relationships with the family were clearly associated with a better treatment outcome. Scores of weighted follow-up findings were calculated to assess patients' status at each follow-up. Progress during the whole follow-up period was measured by the direction of slope calculated from linear regression model for individual scores. The relationship between pre-treatment conditions and patterns of follow-up was evaluated cross-sectionally (answers distribution) and longitudinally (direction of slope). A pattern of shift emerged where different patient groups crossed over to the opposite end of the score scale. Kuwait society's indulgent attitudes towards Kuwaiti patients with alcohol-related problems in employment have to be changed and utilization of the role of the Arab extended family in therapy is stressed. PMID:2884088

Bilal, A M; Kristof, J; Shaltout, A; el-Islam, M F

1987-03-01

202

Study Factors Influencing Ventricular Enlargement in Schizophrenia: A 20 Year Follow-Up Meta-Analysis  

PubMed Central

A meta-analysis was performed on studies employing the ventricular-brain ratio to compare schizophrenic subjects to that of normal controls. This was a follow-up to a similar meta-analysis published in 1992 in which study-, in addition to clinical-, factors were found to contribute significantly to the reported difference between patients with schizophrenia and controls. Seventy-two (N=72) total studies were identified from the peer reviewed literature, 39 from the original meta-analysis, and 33 additional studies published since which met strict criteria for inclusion and analysis– thus representing ~30 years of schizophrenia ventricular enlargement research. Sample characteristics from schizophrenics and controls were coded for use as predictor variables against within sample VBR values as well as for between sample VBR differences. Additionally, a number of factors concerning how the studies were conducted and reported were also coded. Obtained data was subjected to unweighted univariate as well as multiple regression analyses. In particular, results indicated significant differences between schizophrenics and controls in ventricular size but also the influence of the diagnostic criteria used to define schizophrenia on the magnitude of the reported VBR. This suggests that differing factors of the diagnostic criteria may be sensitive to ventricular enlargement and might be worthy of further examination. Interestingly, we observed an inverse relationship between VBR difference and the number of co-authors on the study. This latter finding suggests that larger research groups report smaller VBR differences and may be more conservative or exacting in their research methodology. The diagnostic criteria used for defining schizophrenia were also predictive of between group differences. Analyses weighted by sample size provided identical conclusions. The effects of study factors such as these are helpful for understanding the variation in the size of the reported differences in VBR between patients and controls as well as for understanding the evolution of research on complex clinical syndromes employing neuroimaging morphometrics. PMID:21787868

Sayo, Angelo; Jennings, Robin G.

2012-01-01

203

Follow up study of 70 patients with renal artery stenosis treated by percutaneous transluminal dilatation.  

PubMed Central

Between April 1978 and April 1981, 70 patients with hypertension and renal artery stenosis were treated by percutaneous transluminal arterial dilatation. Selection of the patients was based solely on arteriographic criteria. Arteriography after dilatation showed considerable widening of the stenosed area in all patients. In 65 patients the effect of treatment on the blood pressure was assessed during follow up periods of one to four years. In 14 of these patients the hypertension was cured, in 29 it was improved, and in 22 there was no change. Patients with fibromuscular lesions benefited distinctly more than did those with atheromatous stenosis, only one of the 21 patients with fibromuscular lesions showing no change as compared with 21 of the 44 patients with atheromatous lesions. The only serious complication encountered was microcholesterol emboli, which developed in two patients with severe atheromatous lesions of the aorta. In the atheromatous group age and overall renal function had no influence on the blood pressure response. In the subgroup of patients with a unilateral lesion the renal vein renin ratios and asymmetrical curves obtained by renography had only a very limited predictive value. In experienced hands percutaneous transluminal arterial dilatation is relatively safe, and this study suggests that it should be attempted in all patients with renal artery stenosis. Only in patients with severe atheromatosis of the aorta should the risk associated with the catheterisation be weighed against the 50% or so chance of benefit from the procedure. PMID:6223685

Geyskes, G G; Puylaert, C B; Oei, H Y; Mees, E J

1983-01-01

204

Childhood ADHD and the Emergence of Personality Disorders in Adolescence: A Prospective Follow-up Study  

PubMed Central

Objectives: Adults with ADHD experience considerable functional impairment. However, the extent to which comorbid Axis II personality disorders contribute to their difficulties and whether such comorbidities are associated with the childhood condition or the persistence of ADHD into adulthood remains unclear. Methods: This study examined the presence of personality disorders in a longitudinal sample of adolescents diagnosed with ADHD when they were 7 – 11 years-old, as compared to a matched, never-ADHD, control group. Participants were 16-26 years old at follow-up. Based on a psychiatric interview, the ADHD group was subdivided into those with and without persistent ADHD. Axis II symptoms were assessed using the SCID-II. Data were analyzed using logistic regression and odds ratios (OR) were generated. Results: Individuals diagnosed with childhood ADHD are at increased risk for personality disorders in late adolescence, specifically Borderline (OR = 13.16), Antisocial (OR = 3.03), Avoidant (OR = 9.77), and Narcissistic (OR = 8.69) personality disorders. Those with persistent ADHD were at higher risk for Antisocial (OR = 5.26) and Paranoid (OR = 8.47) personality disorders when compared to those in whom ADHD remitted, but not the other personality disorders. Conclusion: Results suggest that ADHD portends risk for adult personality disorders, but the risk is not uniform across disorders, nor is it uniformly related to child or adult diagnostic status. PMID:19193347

Miller, Carlin J.; Flory, Janine D.; Miller, Scott, R.; Harty, Seth C.; Newcorn, Jeffrey H.; Halperin, Jeffrey M.

2009-01-01

205

Personality as a predictor of depression symptoms in burn patients: a follow-up study.  

PubMed

There is empirical evidence that having some personality characteristics increases the risk of developing depression. This is the first study which analyses the role of personality dimensions, assessed by the Alternative Five Factor Model, in the development of depressive symptoms in adult burn survivors across time. Participants were 109 adult burn survivors admitted to a Burns Unit. Personality was assessed by the Zuckerman-Kuhlman Personality Questionnaire and depression symptoms by the Beck Depression Inventory. After adjusting by age, gender and burn size, results showed that high Neuroticism-Anxiety (N-Anx) and Aggression-Hostility (Agg-Host) were related to higher depression scores when compared with low N-Anx and Agg-Host groups along the six months follow-up. Moreover, Activity and Impulsive-Sensation Seeking factors were involved in statistically significant different depressive symptom development trajectories during the six months after burn. These findings suggest that personality factors could be used to identify the most vulnerable patients, who could develop severe mood symptoms at different points in their recovery. PMID:25145874

Giannoni-Pastor, A; Gomà-i-Freixanet, M; Valero, S; Fidel Kinori, S G; Tasqué-Cebrián, R; Arguello, J M; Casas, M

2015-02-01

206

Screening for celiac disease in 1st degree relatives: a 10-year follow-up study  

PubMed Central

Background Although it is known that first degree relatives of celiac patients have an increased risk for celiac disease few studies are available on its incidence. We investigated the incidence of serologic conversion and of new cases of celiac disease among first degree relatives with negative results at a first screening. Methods From a total of 634 first degree relatives of 186 biopsy-proven celiac disease patients diagnosed between October 2000 and October 2010, 450 subjects agreed to participate in the study (Group I), and underwent serologic screening. Between January 2010 and October 2012, out of the initial group of 450, 205 previously sero-negative subjects consented to participate in a second stage of the study and undergo new serologic testing (Group II). All serologically positive individuals of both groups (I and II) were genotyped for celiac disease-predisposing alleles (HLA-DQ2/DQ8). Results 19 subjects (4.2%) out of the 450 subjects of Group I disclosed positive serologic results, presence of DQ2 and/or DQ8 alleles and celiac disease-compatible mucosal abnormalities. The 205 previously negative first degree relatives from Group II that underwent new serologic testing disclosed eight sero-converted subjects. Mucosal abnormalities in five of these patients confirmed the diagnosis of celiac disease. During the 10-year period of the study the incidence of sero-conversion was 8/205 and the incidence of biopsy-proven celiac disease cases was 5/205. Conclusions Our data are coincident with other works on this subject and confirm once again that relatives of celiac patients, especially first degree relatives are at high risk of developing celiac disease. In view of the relatively low incidence further studies are needed to try to establish a useful and cost-effective algorithm for follow-up of relatives of celiac patients. PMID:24552206

2014-01-01

207

Mechanical Engineering Curricula: A Follow-up Study for the Future Effects of ABET EC2000  

NSDL National Science Digital Library

The Accreditation Board for Engineering and Technology (ABET) is recognized by the U.S. Department of Education as the sole agency responsible for accreditation of educational programs leading to degrees in engineering, engineering technology, and related engineering areas. In the late 1990s, engineering programs began transitioning to a new Engineering Criteria 2000 (EC2000). By 2001, all engineering programs were required to be accredited under the new criteria. The philosophy of Engineering Criteria 2000 is to allow institutions and programs to define their mission and objectives to meet the needs of their constituents and enable program differentiation. Emphasis is placed on continuous improvement of programs based on the input of constituents and a process that links outcomes and assessment to program objectives. This current paper is a follow-up study to a preliminary study conducted by the author in 2000 that looked at the initial effects of ABET EC2000. The earlier study examined selected mechanical engineering programs to discern the impact of EC2000 on curriculum development during the initial implementation phase of the new criteria. Data on the layout and composition of mechanical engineering curricula for nine schools in the United States with Ph.D. programs and nine schools without Ph.D. programs was presented and is updated in this current work. Current results are also compared to a study by Robert E. Mates from the State University of New York at Buffalo entitled a Survey of Undergraduate ME Programs, conducted in 1987. The conclusions identify changes that have occurred in mechanical engineering curricula as the EC2000 assessment process has matured.

Whiteman, Wayne

208

Usefulness of follow-up electrophysiologic study and event monitoring after successful radiofrequency catheter ablation of supraventricular tachycardia  

Microsoft Academic Search

We assessed the usefulness of routine follow-up electrophysiologic studies after successful catheter ablation for supraventricular tachycardia and the role of event monitoring as an alternative modality in 310 patients at 11 centers using an investigational catheter ablation system with closed-loop temperature control. A routine follow-up electrophysiologic study between 1 and 3 months after ablation was required as part of the

Alan B. Wagshal; Luis A. Pires; Patrick G. Yong; Suzan A. Moser; Frank Mazzola; Robert S. Mittleman; Shoei K. Stephen Huang

1995-01-01

209

Inadequate Follow-up of Abnormal Screening Mammograms: Findings From the Race Differences in Screening Mammography Process Study (United States)  

Microsoft Academic Search

Objective: Despite relatively high mammography screening rates, there are reports of inadequate follow-up of abnormal results. Our objective was to identify factors associated with inadequate follow-up, and specifically, to determine if this outcome differed by race\\/ethnicity. Methods: We studied 176 subjects with abnormal or inconclusive mammograms identified from a prospective cohort study of African-American (n = 635) and White (n

Beth A. Jones; Amy Dailey; Lisa Calvocoressi; Kam Reams; Stanislav V. Kasl; Carol Lee; Helen Hsu

2005-01-01

210

Physical Activity and Stroke Incidence in Women and Men The NHANES I Epidemiologic Follow-up Study  

Microsoft Academic Search

To test the hypothesis that physical inactivity Is associated with increased stroke risk in women and men, the authors analyzed data from a longitudinal cohort study with three follow-up data collection waves. In the National Health and Nutrition Examination Survey I (NHANES 0 Epidemiologic Follow-up Study, 7,895 white persons and black persons aged 45-74 years were examined in 1971-1975 as

Richard F. Gillum; Michael E. Mussolino; Deborah D. Ingram

1996-01-01

211

Head injury outcome up to ten years later.  

PubMed

Head injury outcome was studied in 63 severe traumatic brain-injured (TBI) victims up to ten years after injury. Extent of improvement and residual deficits in physical and mental impairment and mood and frustration tolerance changes are reported. The impact of these changes upon ability to work and to establish living situations is presented. It was found that long-term outcome is related significantly both to elapsed time between injury and admission to an intensive rehabilitation hospital program and to level of disability at admission. Major problems and needs at follow-up are reported. Thirteen demographic and clinical profile parameters are suggested to permit meaningful comparisons of long-term outcome among different groups of TBI victims. PMID:2596962

Rappaport, M; Herrero-Backe, C; Rappaport, M L; Winterfield, K M

1989-12-01

212

Work, Diabetes and Obesity: A Seven Year Follow-Up Study among Danish Health Care Workers  

PubMed Central

Objectives The rise in prevalence of diabetes is alarming and research ascribes most of the increase to lifestyle. However, little knowledge exists about the influence of occupational factors on the risk for developing diabetes. This study estimates the importance of work and lifestyle as risk factors for developing diabetes mellitus among healthcare workers and explores the association of work factors and obesity, which is a risk factor for diabetes. Methods Questionnaire-based prospective cohort study among 7,305 health care workers followed for seven years in the Danish National Diabetes Register. We used bivariate comparisons to give an unadjusted estimate of associations, followed by adjusted survival analysis and logistic regression models to estimate the influences of potential risk factors related to job, health and lifestyle on diabetes and obesity. Results During seven years of follow up, 3.5% of participants developed diabetes, associated with obesity (HR ?=? 6.53; 95% CI 4.68–9.10), overweight (HR ?=? 2.89; CI 2.11–3.96) age 50–69 y (HR ?=? 2.27; 95% CI 1.57–3.43) and high quality of leadership (HR ?=? 1.60; CI 1.19–2.16). Obesity at baseline was most common among the youngest employees, and was mainly associated with developing diabetes (OR ?=? 3.84; CI 2.85–5.17), impaired physical capacity and physical inactivity. In the occupational setting, obesity was associated with shift work, severe musculoskeletal pain, low influence, but also by good management, fewer role conflicts and a positive work-life balance. Looking only at non-smokers, removed the influence of age and pain. However, non-smokers also had higher depression scores and more role conflicts. Conclusions Confirming obesity as the strongest risk factor for developing diabetes, the present study identified few occupational risk factors. However, obesity, the key risk factor for diabetes, had a more variable relation with work than did diabetes. PMID:25068830

Poulsen, Kjeld; Cleal, Bryan; Clausen, Thomas; Andersen, Lars L.

2014-01-01

213

Long-term follow-up study of patients with phenylketonuria detected by the newborn screening programme in Japan.  

PubMed

The objective of this report is to determine the need for and value of the long-term follow-up study of phenylketonuria (PKU) patients detected by newborn screening (NBS) in Japan. NBS was started in 1977 and the nationwide follow-up study of the identified patients was introduced into the NBS system. Outcome data from the continuous follow-up study showed in 1993 that IQ of PKU patients was inversely correlated with blood phenylalanine levels. Accordingly, in 1995, new treatment guidelines were issued that involved more stringent restriction of phenylalanine levels. Follow-up data confirmed that mean blood phenylalanine levels decreased after the introduction of the new guidelines, which included the recommendation to start dietary treatment within 20 days postpartum. Follow-up data also confirmed that dietary treatment did in fact commence earlier after the guidelines were issued. The need for lifelong dietary treatment is a difficult issue and the number of patients who stop dietary treatment was found to increase gradually with age. At present 60% of PKU patients born between 1977 and 1981 have stopped their dietary restriction of phenylalanine. The data gained from NBS and the long-term follow-up study were found to be valuable for the improvement of blood phenylalanine levels for patients with PKU, indicating the need for parties responsible for NBS and the follow-up study of the identified patients to work cooperatively. Further, the evaluations of the effectiveness of the two initiatives as well as the treatment guidelines issued should be based on outcome data, which depend on the continuation of the follow-up study of patients with PKU. PMID:17641826

Aoki, K; Ohwada, M; Kitagawa, T

2007-08-01

214

Follow-Up Study of Former Students of the Data Processing Program. Volume XVI, No. 3.  

ERIC Educational Resources Information Center

In spring 1987, a follow-up survey was conducted of former William Rainey Harper College (WRHC) students who had taken five or more data processing courses at the college between 1980 and 1986. The survey focused on the students' employment status and educational intent while attending WRHC, their present employment situation, and their evaluation…

Rilki, Ernest; Lucas, John A.

215

A twenty-five year follow-up study of ten exceptionally creative adolescent girls.  

PubMed

A 25-yr. follow-up of 10 women identified as highly creative during adolescence indicated that most believed they had actualized their creative potential to a moderately high degree. However, only one woman stated that creative expression was a dominant life theme and primary commitment. Factors that facilitate and inhibit creativity over a lifetime are discussed. PMID:2034770

Cangelosi, D M; Schaefer, C E

1991-02-01

216

Freshman Withdrawal from College: A Positive Step toward Identity Formation?: A Follow-Up Study.  

ERIC Educational Resources Information Center

Males and females who withdrew from college during their freshman year were divided into withdrawers vs continuers, transfers vs nontransfers, and withdrew passing vs withdrew failing. Responses and follow-up interviews indicated that withdrawal form college can be a positive step toward separation from parents and identity formation. (Author/JAC)

Timmons, Frank R.

1978-01-01

217

A Long-Term Follow-Up Study in Essential Cryoglobulinemia  

Microsoft Academic Search

In a case series of 56 patients with essential cryoglobulinemia, 35 were followed-up for 4–13 years (mean 7 years). A membranous proliferative glomerulonephritis, which in about half the cases showed a progression to renal insufficiency, was the commonest complication, observed in more than one third of the patients. In 2 patients hepatic cirrhosis became manifest after a completely asymptomatic period

F. Invernizzi; P. Pioltelli; R. Cattaneo; V. Gavazzeni; P. Borzini; G. Mont; C. Zanussi

1979-01-01

218

Progressive chronic Chagas heart disease ten years after treatment with antiTrypanosoma cruzi nitroderivatives. Am J Trop Med Hyg  

E-print Network

Abstract. A randomized ten-year follow-up study involving 91 Chagas patients and 41 uninfected controls was undertaken to determine the effectiveness of nitroderivative therapy. Anti-Trypanosoma cruzi antibodies were con-sistently lower one year after treatment than 10 years thereafter (P 0

Liana Lauria-pires; Maria S. Braga; Ana C. Vexenat; Nadjar Nitz; Augusto Simo Es-barbosa; Douglas L. Tinoco; Antonio R. L. Teixeira

2000-01-01

219

Six-Month Follow-Up Study of Ultrarapid Opiate Detoxification With Naltrexone  

PubMed Central

Background: Illicit opiate use has an increasing incidence and prevalence, which increases mortality and morbidity, marginalization, and criminal behaviors, and causes major adverse effects on society. Objectives: This study aimed to investigate and follow the outcome of patients who underwent ultrarapid opiate detoxification (UROD) prospectively. Patients and Methods: In this randomized clinical trial, 64 patients who underwent UROD were evaluated. The opiate antagonist regimen of naloxone was administered intravenously under general anesthesia, and detoxification was confirmed by naloxone challenge test. All patients were cared in intensive care unit (ICU) for 24 hours, and oral naltrexone was prescribed the next day, after recovery and discharge. Patients were followed up for one month after the procedure. Relapse was considered if routine use of opiates (daily use for at least two weeks) was reported by the patient after detoxification. The data was analyzed by SPSS 16.5 and the study was performed using descriptive analysis and Chi square test. Results: All 64 participants were opiate-dependent males (ASA physical status of I or II) who aged over 18 years with a mean age of 31.11 ± 8.93 years at the time of UROD. One month after UROD, 48 patients (75%) reported relapse and 16 (25%) reported abstinence; however, four patients of the non-relapsed group reported one episode of opiate use. There was no significant difference between relapsed and non-relapsed patients regarding their marital status, level of education, and family history of opiate dependency (P > 0.05). Conclusions: Although UROD by naloxone is a safe and effective method of detoxification, if used alone, it has a very high relapse rate in long term. PMID:25741479

Forozeshfard, Mohammad; Hosseinzadeh Zoroufchi, Babak; Saberi Zafarghandi, Mohammad Bagher; Bandari, Razieh; Foroutan, Behzad

2014-01-01

220

Suicide following the death of a sibling: a nationwide follow-up study from Sweden  

PubMed Central

Objectives The death of a sibling can trigger grief and depression. Sibling deaths from external causes may be particularly detrimental, since they are often sudden. We aimed to examine the association between the death of an adult sibling from external causes and the risk of suicide among surviving siblings up to 18?years after bereavement. We adjusted for intrafamily correlation in death risks, which might occur because of shared genetics and shared early-life experiences of siblings in the same family. Design A follow-up study between 1981 and 2002 based on the total population. Setting Sweden. Participants Swedes aged 25–64?years (n=1?748?069). Primary and secondary outcome measures Suicide from the Swedish cause of death register. Results An increased risk of mortality from suicide was found among persons who had experienced the death of a sibling. In women, the suicide risk was 1.55 times that of non-bereaved persons (95% CI 0.99 to 2.44), and in men it was 1.28 times higher (95% CI 0.93 to 1.77). If one sibling committed suicide, the risk of the remaining sibling also committing suicide was 3.19 (95% CI 1.23 to 8.25) among women and 2.44 (95% CI 1.34 to 4.45) among men. Associations with other main causes of death—such as external other than suicide, cardiovascular diseases or cancer—were generally much smaller and statistically not significant in either sex. We found no clear support for a specific time pattern according to time since a sibling's death. Conclusions Our study provided evidence for suicide risk associated with the death of a sibling at adult age, revealing that bereaved persons’ risk of suicide is higher when siblings die from suicide, even when adjusting for intrafamily correlation in death risks. PMID:23624991

Rostila, Mikael; Saarela, Jan; Kawachi, Ichiro

2013-01-01

221

A follow-up study of early interceptive treatment of primary anterior crossbites.  

PubMed

The purpose of this study was to investigate the outcome of early interceptive treatment of primary anterior crossbites with posterior occlusal acrylic resin blocks in combination with a 2 × 4 appliance, and to examine the differences in craniofacial morphology between the stable and relapse groups. Lateral cephalograms of 46 subjects (17 males and 29 females; average mean age 4 years 2 months ± 5 months) with a primary anterior crossbite were obtained before (T0) and immediately after (T1) treatment and at a 6 year follow-up (T2). The patients were assigned to either a stable (n = 35; 13 males and 22 females) or a relapse (n = 11; 4 males and 7 females) group according to the amount of overjet when the permanent incisors had erupted. The differences in craniofacial morphology between the groups were compared using a two-tailed t-test. The results revealed that the relapse subjects had a more forward position of the mandible relative to the cranial base and maxilla, a longer mandible and an increased gonial angle at T0. At T1, both groups had a positive overjet, but the treatment changes were different. Between T1 and T2, the maxillary length (A'-Ptm') increased less in the relapse group, the angle between the posterior border of the mandibular ramus and SN plane (Ram-SN) decreased and gonial angle increased and vice versa in the stable group. When posterior bite raising and 2 × 4 appliance therapy are used to correct primary anterior crossbites, all patients showed an immediate positive treatment response, whereas approximately one-quarter of subjects relapsed into a reverse overjet when the permanent incisors had erupted, mainly because of a more severe Class III craniofacial morphology at T1 and unfavourable growth during T1-T2. PMID:21239395

Ge, Yuanshu; Liu, Jin; Guo, Xin; Han, Jianli

2011-10-01

222

Prevalence, incidence and predictive factors for hand eczema in young adults – a follow-up study  

PubMed Central

Background Hand eczema is common in the general population and affects women twice as often as men. It is also the most frequent occupational skin disease. The economic consequences are considerable for society and for the affected individuals. Methods To investigate the prevalence and incidence of hand eczema and to evaluate risk factors for development of hand eczema in young adults. Subjects and methods; This is a prospective follow-up study of 2,403 young adults, 16 – 19 years old in 1995 and aged 29 – 32 years, 13 years later, in 2008. They completed a postal questionnaire that included questions regarding one-year prevalence of hand eczema, childhood eczema, asthma, rhino-conjunctivitis and factors considered to affect hand eczema such as hand-washing, washing and cleaning, cooking, taking care of small children and usage of moisturisers. These factors were evaluated with the multinominal logistic regression analysis. Results The one-year prevalence of hand eczema was 15.8% (females 20.3% and males 10.0%, p?

2013-01-01

223

Language exposure induced neuroplasticity in the bilingual brain: A follow-up fMRI study.  

PubMed

Although several studies have shown that language exposure crucially influence the cerebral representation of bilinguals, the effects of short-term change of language exposure in daily life upon language control areas in bilinguals are less known. To explore this issue, we employed follow-up fMRI to investigate whether differential exposure induces neuroplastic changes in the language control network in high-proficient Cantonese (L1)-Mandarin (L2) early bilinguals. The same 10 subjects underwent twice BOLD-fMRI scans while performing a silent narration task which corresponded to two different language exposure conditions, CON-1 (L1/L2 usage percentage, 50%:50%) and CON-2 (L1/L2 usage percentage, 90%:10%). We report a strong effect of language exposure in areas related to language control for the less exposed language. Interestingly, these significant effects were present after only a 30-day period of differential language exposure. In detail, we reached the following results: (1) the interaction effect of language and language exposure condition was found significantly in the left pars opercularis (BA 44) and marginally in the left MFG (BA 9); (2) in CON-2, increases of activation values in L2 were found significantly in bilateral BA 46 and BA 9, in the left BA44, and marginally in the left caudate; and (3) in CON-2, we found a significant negative correlation between language exposure to L2 and the BOLD activation value specifically in the left ACC. These findings strongly support the hypothesis that even short periods of differential exposure to a given language may induce significant neuroplastic changes in areas responsible for language control. The language which a bilingual is less exposed to and is also less used will be in need of increased mental control as shown by the increased activity of language control areas. PMID:25461703

Tu, Liu; Wang, Junjing; Abutalebi, Jubin; Jiang, Bo; Pan, Ximin; Li, Meng; Gao, Wei; Yang, Yuchen; Liang, Bishan; Lu, Zhi; Huang, Ruiwang

2015-03-01

224

Specific antibody deficiency in children with recurrent respiratory infections: a controlled study with follow-up  

PubMed Central

Specific antibody deficiency (SAD) to unconjugated pneumococcal vaccine (PPV) is an established primary B cell immunodeficiency. The occurrence and natural history of SAD in children is unclear. We conducted an observational study to identify SAD in children with recurrent respiratory infections. Ninety-nine children, mean age 5·9 (range 2–16) years, with recurrent or severe infections were vaccinated with PPV; serum antibody concentrations for serotypes 4, 6B, 9V, 14, 18C, 19F and 23F were measured before and 2 weeks after vaccination with enzyme immunoassay. The retrospective control group consisted of 89 healthy children matched for age and gender. No children had received previous conjugated pneumococcal vaccine (PCV) or PPV. The structured history of infectious diseases of all participants was collected. Ten of 91 (11%) children (eight excluded due to immunoglobulin G subclass deficiency) with recurrent respiratory infections had SAD. In the control group, three children (3%) responded inadequately to PPV (P = 0·05). Most children with SAD also had many other minor immune defects. After 0·5–5 years (medium 3·8), eight children with SAD were revaccinated with PPV; five responded adequately and three inadequately. Two SAD children were revaccinated with PCV, one developed an adequate and one an inadequate response. Two children with SAD received treatment with intravenous immunoglobulin; the remaining eight children recovered without replacement therapy during the follow-up. SAD is common in young children with recurrent respiratory infections, but it is often transient and resolves itself within a few years without specific treatment. PMID:23574320

Ruuskanen, O; Nurkka, A; Helminen, M; Viljanen, M K; Käyhty, H; Kainulainen, L

2013-01-01

225

A FOLLOW UP STUDY ON REVISED NATIONAL TUBERCULOSIS CONTROL PROGRAMME (RNTCP): RESULTS FROM A SINGLE CENTRE STUDY  

PubMed Central

Objective: To know the follow up status of tuberculosis patients after 1 year of completion of treatment in RNTCP. Materials & Methods: Those patients of tuberculosis, who were registered from June 2003 to June 2004 at DOTS centre of our institution, were followed up at their homes after one year of completion of treatment between August 2005 and August 2006, with the help of health visitor. Patients were followed up clinically and symptomatic patients were also followed radiologically as well as bacteriologicalty. Results of the study were recorded in terms of number of patients remained asymptomatic, number of patients relapsed and number of patients died. Results: Out of 237 patients registered, 8 patients died during treatment period, 12 patients defaulted the treatment, the number of failures was 5 and 212 patients were declared cured/treatment completed. Out of these 212 patients 60 were unavailable for interview due to various reasons. The study observed that out of a total of 152 patients interviewed, 137 patients (90.1%) of remained asymptomatic, 11 patients (7.2%) had relapsed and 4 patients (2.6%) died during follow up. Conclusion: The study observed that majority of patients (90.1%) re-mained asymptomatic after the completion of one year of treatment under DOTS. PMID:21264079

Prasad, R.; Verma, S. K.; Shrivastava, P.; Kant, S.; Kushwaha, R. A. S.; Kumar, S.

2008-01-01

226

Estimating bias from loss to follow-up in a prospective cohort study of bicycle crash injuries  

PubMed Central

Background Loss to follow-up, if related to exposures, confounders and outcomes of interest, may bias association estimates. We estimated the magnitude and direction of such bias in a prospective cohort study of crash injury among cyclists. Methods The Taupo Bicycle Study involved 2590 adult cyclists recruited from New Zealand's largest cycling event in 2006 and followed over a median period of 4.6?years through linkage to four administrative databases. We resurveyed the participants in 2009 and excluded three participants who died prior to the resurvey. We compared baseline characteristics and crash outcomes of the baseline (2006) and follow-up (those who responded in 2009) cohorts by ratios of relative frequencies and estimated potential bias from loss to follow-up on seven exposure-outcome associations of interest by ratios of HRs. Results Of the 2587 cyclists in the baseline cohort, 1526 (60%) responded to the follow-up survey. The responders were older, more educated and more socioeconomically advantaged. They were more experienced cyclists who often rode in a bunch, off-road or in the dark, but were less likely to engage in other risky cycling behaviours. Additionally, they experienced bicycle crashes more frequently during follow-up. The selection bias ranged between ?10% and +9% for selected associations. Conclusions Loss to follow-up was differential by demographic, cycling and behavioural risk characteristics as well as crash outcomes, but did not substantially bias association estimates of primary research interest. PMID:24336816

Tin Tin, Sandar; Woodward, Alistair; Ameratunga, Shanthi

2014-01-01

227

Ten?Year Blood Pressure Trajectories, Cardiovascular Mortality, and Life Years Lost in 2 Extinction Cohorts: the Minnesota Business and Professional Men Study and the Zutphen Study  

PubMed Central

Background Blood pressure (BP) trajectories derived from measurements repeated over years have low measurement error and may improve cardiovascular disease prediction compared to single, average, and usual BP (single BP adjusted for regression dilution). We characterized 10?year BP trajectories and examined their association with cardiovascular mortality, all?cause mortality, and life years lost. Methods and Results Data from 2 prospective and nearly extinct cohorts of middle?aged men—the Minnesota Business and Professional Men Study (n=261) and the Zutphen Study (n=632)—were used. BP was measured annually during 1947–1957 in Minnesota and 1960–1970 in Zutphen. BP trajectories were identified by latent mixture modeling. Cox proportional hazards and linear regression models examined BP trajectories with cardiovascular mortality, all?cause mortality, and life years lost. Associations were adjusted for age, serum cholesterol, smoking, and diabetes mellitus. Mean initial age was about 50 years in both cohorts. After 10 years of BP measurements, men were followed until death on average 20 years later. All Minnesota men and 98% of Zutphen men died. Four BP trajectories were identified, in which mean systolic BP increased by 5 to 49 mm Hg in Minnesota and 5 to 20 mm Hg in Zutphen between age 50 and 60. The third systolic BP trajectories were associated with 2 to 4 times higher cardiovascular mortality risk, 2 times higher all?cause mortality risk, and 4 to 8 life years lost, compared to the first trajectory. Conclusions Ten?year BP trajectories were the strongest predictors, among different BP measures, of cardiovascular mortality, all?cause mortality, and life years lost in Minnesota. However, average BP was the strongest predictor in Zutphen. PMID:25753924

Tielemans, Susanne M. A. J.; Geleijnse, Johanna M.; Menotti, Alessandro; Boshuizen, Hendriek C.; Soedamah?Muthu, Sabita S.; Jacobs, David R.; Blackburn, Henry; Kromhout, Daan

2015-01-01

228

A follow up study of vibration induced white finger in compensation claimants  

PubMed Central

Aims: To follow up vibration induced white finger (VWF) in a selected group of 73 vibration exposed workers who claimed unsuccessfully for VWF compensation at a first examination. Methods: The VWF claimants were sent to our unit by the National Insurance Institute. The basic compensatory criteria included a positive history of VWF and abnormal cold response of the digital arteries. Following the first unsuccessful examination, over a mean time period of 4.1 (range 1–11) years the National Insurance Institute requested a second examination for all 73 claimants and a third examination for 29. During the follow up period, all subjects continued to work with vibratory tools. Results: There were 14 new cases who reported white finger during the follow up period. In the new VWF cases, finger blanching attacks became visible after about 3.5 years since the first examination. All incident cases of anamnestic VWF showed an abnormal cold response in the digital arteries and obtained compensation according to the basic compensatory criteria. In the entire sample of VWF claimants, there was a discrepancy between positive history of VWF symptoms at medical interview (55%) and abnormal cold provocation outcomes (19%). Digital arterial hyperresponsiveness to cold was associated with both VWF symptoms and the duration of vibration exposure since the first examination. Over the follow up period, a significant increase in the vasoconstrictor response to cold was observed in the vibration exposed workers with no symptoms of finger whiteness. Abnormal cold response was not associated with either age or smoking habit. Conclusions: Cold test measuring finger systolic blood pressure may be considered a useful laboratory method to confirm objectively VWF symptoms and to disclose abnormal cold induced vasoconstrictor response in vibration exposed workers with a negative history of VWF. Medical interview outcomes should be interpreted with caution in medicolegal situations involving VWF claimants. PMID:15778256

Bovenzi, M; Della, V; Negro, C

2005-01-01

229

Childhood predictors of smoking in adolescence: a follow-up study of Montreal schoolchildren  

Microsoft Academic Search

Background: The factors that cause children to become smokers in adolescence remain unclear. Although parental smoking and peer pressure may play a role, physiological factors such as lung volume have also been identified. Methods: To investigate these and other possible childhood pre- dictors of teenage smoking, we gathered follow-up data on 191 Montréal schoolchildren, aged 5-12 years (average 9.2 yr)

Margaret R. Becklake; Heberto Ghezzo; Pierre Ernst

2005-01-01

230

Crack Cocaine: A Five-Year Follow-Up Study of Treated Patients  

Microsoft Academic Search

Objectives: To follow-up a group of 131 crack cocaine users and examine drug use, treatment experience, employment status, involvement in crime and mortality at 2 and 5 years. Methods: Consecutive crack-dependent patients who were admitted to a detoxification unit in São Paulo between 1992 and 1994 were re-interviewed on two occasions: 1995–1996 and 1998–1999. Results: 5 years after treatment information

M. Ribeiro; J. Dunn; R. Sesso; M. S. Lima; R. Laranjeira

2007-01-01

231

[5 years follow-up study of stroke patients over 65 years of age].  

PubMed

A total of 289 stroke patients over age 65 were followed-up 5 years post-discharge from in-patient rehabilitation. Predictors of the course following discharge are investigated and geriatric rehabilitation assessed based on data gathered during in-patient rehabilitation as well as follow-up findings. 40% of the patients were alive 5 years post-discharge; the average annual death rate of 14.6% had been three times higher than among a control group. 67% are living in their own home, 21% in a nursing facility, and 12% in a residence for the elderly; only 3 of the surviving patients had to move to a nursing home post discharge. The patients' independence had reduced by an average 5 points on the Barthel index. Negative predictors for survival had been the presence of cardiac disease, Diabetes mellitus, psycho-organic syndrome and depression at discharge. However, as is the case for age as such, these conditions do not affect survivors' functional outcomes. Two thirds of the patients consider their state of health as constant or improved; only one fifth were rated as having a poor quality of life. The data gathered for the follow-up patients show that geriatric stroke rehabilitation is worthwhile. PMID:7973060

Vogel, J

1994-08-01

232

Bacterial infections in patients with type 1 diabetes: a 14-year follow-up study  

PubMed Central

Objective This study explored the annual occurrence/incidence of bacterial infections, and their association with chronic hyperglycemia and diabetic nephropathy, in patients with type 1 diabetes. Design In a register-based follow-up study, we investigated the frequency of bacterial infections in patients with type 1 diabetes (n=4748) and age-matched and sex-matched non-diabetic control (NDC) subjects (n=12?954) using nationwide register data on antibiotic drug prescription purchases and hospital discharge diagnoses, collected between 1996 and 2009. Diabetic nephropathy was classified based on the urinary albumin excretion rate (AER). Results The hospitalization rate due to bacterial infections was higher in patients with diabetes compared with NDCs (rate ratio (RR) 2.30 (95% CI 2.11 to 2.51)). The rate correlated with the severity of diabetic nephropathy: RR for microalbuminuria was 1.23 (0.94 to 1.60), 1.97 (1.49 to 2.61) for macroalbuminuria, 11.2 (8.1 to 15.5) for dialysis, and 6.72 (4.92 to 9.18) for kidney transplant as compared to patients with diabetes and normal AER. The annual number of antibiotic purchases was higher in patients with diabetes (1.00 (1.00 to 1.01)) as compared with NDCs (0.47 (0.46 to 0.47)), RR=1.71 (1.65 to 1.77). Annual antibiotic purchases were 1.18-fold more frequent in patients with microalbuminuria, 1.29-fold with macroalbuminuria, 2.43-fold with dialysis, and 2.74-fold with kidney transplant as compared to patients with normal AER. Each unit of increase in glycated hemoglobin was associated with a 6–10% increase in the number of annual antibiotic purchases. Conclusions The incidence of bacterial infections was significantly higher in patients with type 1 diabetes compared with age-matched and sex-matched NDC subjects, and correlated with the severity of diabetic nephropathy in inpatient and outpatient settings.

Simonsen, Johan R; Harjutsalo, Valma; Järvinen, Asko; Kirveskari, Juha; Forsblom, Carol; Groop, Per-Henrik; Lehto, Markku

2015-01-01

233

Oligometastases Treated With Stereotactic Body Radiotherapy: Long-Term Follow-Up of Prospective Study  

SciTech Connect

Purpose: To analyze the long-term survival and tumor control outcomes after stereotactic body radiotherapy (SBRT) for metastases limited in number and extent. Methods and Materials: We prospectively analyzed the long-term overall survival (OS) and cancer control outcomes of 121 patients with five or fewer clinically detectable metastases, from any primary site, metastatic to one to three organ sites, and treated with SBRT. Freedom from widespread distant metastasis (FFDM) was defined as metastatic disease not amenable to local therapy (i.e., resection or SBRT). Prognostic variables were assessed using log-rank and Cox regression analyses. Results: For breast cancer patients, the median follow-up was 4.5 years (7.1 years for 16 of 39 patients alive at the last follow-up visit). The 2-year OS, FFDM, and local control (LC) rate was 74%, 52%, and 87%, respectively. The 6-year OS, FFDM, and LC rate was 47%, 36%, and 87%, respectively. From the multivariate analyses, the variables of bone metastases (p = .057) and one vs. more than one metastasis (p = .055) were associated with a fourfold and threefold reduced hazard of death, respectively. None of the 17 bone lesions from breast cancer recurred after SBRT vs. 10 of 68 lesions from other organs that recurred (p = .095). For patients with nonbreast cancers, the median follow-up was 1.7 years (7.3 years for 7 of 82 patients alive at the last follow-up visit). The 2-year OS, FFDM, and LC rate was 39%, 28%, and 74%, respectively. The 6-year OS, FFDM, and LC rate was 9%, 13%, and 65%, respectively. For nonbreast cancers, a greater SBRT target volume was significantly adverse for OS (p = .012) and lesion LC (p < .0001). Patients whose metastatic lesions, before SBRT, demonstrated radiographic progression after systemic therapy experienced significantly worse OS compared with patients with stable or regressing disease. Conclusions: Select patients with limited metastases treated with SBRT are long-term survivors. Future research should address the therapeutic benefit of SBRT for these patients.

Milano, Michael T., E-mail: MTMilano@yahoo.com [Department of Radiation Oncology, University of Rochester Medical Center, Rochester, NY (United States); Katz, Alan W.; Zhang Hong [Department of Radiation Oncology, University of Rochester Medical Center, Rochester, NY (United States); Okunieff, Paul [Department of Radiation Oncology, University of Rochester Medical Center, Rochester, NY (United States); Department of Radiation Oncology, University of Florida, Gainesville, FL (United States)

2012-07-01

234

Attachment of Community Nurses to General Practices. A Follow-up Study  

PubMed Central

A follow-up survey has shown that in a two-year period the number of community nurses working in general practice attachment schemes rose from 11 to 24% (32% in counties, 13% in county boroughs, and 12% in London boroughs). The proportion of health visitors and home nurses rose from 15 to 29% and from 9 to 25% respectively. Reasons given for the 23 attachment schemes which were discontinued included administrative and personality problems. Careful preparation and continuing support, for both the general practitioners and the community nurses, are stressed for the success of these schemes. PMID:5471753

Anderson, J. A. D.; Draper, P. A.; Kincaid, I. T.; Ambler, M. C.

1970-01-01

235

Maintaining Superior Follow-Up Rates in a Longitudinal Study: Experiences from the College Life Study  

PubMed Central

Longitudinal studies are often considered to be a gold standard for research, but the operational management of such studies is not often discussed in detail; this paper describes strategies used to track and maintain high levels of participation in a longitudinal study involving annual personal interviews with a cohort of 1,253 undergraduates (first-time, first-year students at time of enrollment) at a large public mid-Atlantic university. PMID:22247739

Vincent, Kathryn B.; Kasperski, Sarah J.; Caldeira, Kimberly M.; Garnier-Dykstra, Laura M.; Pinchevsky, Gillian M.; O’Grady, Kevin E.; Arria, Amelia M.

2011-01-01

236

Pollicisation of the index finger. A 27-year follow-up study.  

PubMed

We have reviewed 11 patients with congenital absence of the thumb, treated by pollicisation of the index finger, after follow-up for 20 to 38 years. Seven of the hands also had an associated radial club-hand deformity. Function as assessed by the Percival score was excellent in six, good in three, fair in two and poor in four; three of the poor results were in patients with radial club hand. Ten of the 15 transfers were used as normal thumbs, but in five hands function required trick movements. Of the seven unilateral cases, two transplants were used as the dominant hand, and in another two thumb strength was more than 50% of that on the opposite side. For patients with isolated congenital absence of the thumb, pollicisation of the index finger gives good functional and cosmetic results which are maintained. The results are less reliable for those with radial club hand. PMID:9699826

Clark, D I; Chell, J; Davis, T R

1998-07-01

237

Long-term follow-up of cryopreserved corneal endothelium. A specular microscopic study.  

PubMed

This paper deals with the long-term survival of corneal transplant endothelial cells. Endothelia of 17 cryopreserved corneal transplants were photographed with a specular microscope, first 1.5 years (mean) following transplantation, and again 10 years later. All transplants were absolutely clear. The mean cell loss was 23% in 12 years. After 2 to 14 years post-operatively the cell loss was noticed to be only 13.6% (from 990 +/- 255 cells/mm2 to 855 +/- 213 cells/mm2). It seems that endothelial cells of cryopreserved corneal grafts, although few in number, are still quite resistant and viable after a long follow-up time and survive like endothelial cells after preservation in tissue culture media. PMID:3068949

Ruusuvaara, P; Setälä, K

1988-12-01

238

SLUDGE BATCH 4 FOLLOW-UP QUALIFICATION STUDIES TO EVALUATE HYDROGEN GENERATION  

SciTech Connect

Follow-up testing was conducted to better understand the excessive hydrogen generation seen in the initial Sludge Batch 4 (SB4) qualification Sludge Receipt and Adjustment Tank/Slurry Mix Evaporator (SRAT/SME) simulation in the Savannah River National Laboratory (SRNL) Shielded Cells. This effort included both radioactive and simulant work. The initial SB4 qualification test produced 0.59 lbs/hr hydrogen in the SRAT, which was just below the DWPF SRAT limit of 0.65 lbs/hr, and the test produced over 0.5 lbs/hr hydrogen in the SME cycle on two separate occasions, which were over the DWPF SME limit of 0.223 lbs/hr.

Pareizs, J; David Koopman, D; Dan Lambert, D; Cj Bannochie, C

2007-08-23

239

Five-year follow-up study of the prevalence and progression of pulmonary hypertension in systemic lupus erythematosus  

Microsoft Academic Search

The purpose of this study was to determine the prevalence and progression of pulmonary hypertension over a 5-year follow-up period in 28 patients with systemic lupus erythematosus (SLE) who were originally enrolled in an echocardiographic study of pulmonary hypertension in 1985 and 1986. Twenty healthy volunteers without cardiac or pulmonary disease participated as normal controls. Each patient and control underwent

Timothy M. Winslow; Maxim A. Ossipov; Gary P. Fazio; Jay S. Simonson; Rita F. Redberg; Nelson B. Schiller

1995-01-01

240

Child Development Centers 1977 Evaluation Report. Volume II: A Follow-Up Study. Report No. 78-2.  

ERIC Educational Resources Information Center

This report summarizes the results of a study of the Child Development Centers (CDC), a program operated by the Seattle, Washington public schools to provide social services to students from four to eight years old. Preliminary results from a long-term follow-up study of students successfully terminated from the CDC program between 1973 and 1977…

Crockett, Geraldine T.

241

Delirium episode as a sign of undetected dementia among community dwelling elderly subjects: a 2 year follow up study  

Microsoft Academic Search

Cognitive decline is commonly stated as one of the main risk factors for delirium. The aim was to assess the importance of a delirium episode as a symptom of an underlying dementia among community dwelling healthy elderly people in a prospective 2 year follow up study. The study patients consisted of 51 people living at home and older than 65

Terhi Rahkonen; Riitta Luukkainen-Markkula; Satu Paanila; Juhani Sivenius; Raimo Sulkava

2000-01-01

242

A Negative Finding in an Exercise Test Is Reliable among Elderly People: A Follow-Up Study  

Microsoft Academic Search

Background: Coronary heart disease (CHD) is very common among elderly people. Objective: To specify the diagnostic value of bicycle exercise tests conducted for elderly patients by trained general practitioners in primary health care. Methods: We performed a 2-year follow-up study at the Kangasala Health Centre, Finland. The study population comprised all patients at least 60 years old (n = 311)

Markku Sumanen; Kari Mattila

2007-01-01

243

1990 Follow-up of Former JCCC Students Currently Enrolled at Four-Year Colleges or Universities: A Transfer Study.  

ERIC Educational Resources Information Center

In 1990, a follow-up study was conducted of former Johnson County Community College (JCCC) students who transferred to four-year colleges and universities during 1989. The study sought to provide information concerning JCCC's role in preparing students for transfer, assess students' perceptions of their educational experiences at JCCC, and gather…

Johnson County Community Coll., Overland Park, KS. Office of Institutional Research.

244

Ensuring Retention in Longitudinal Studies: A Practical Evaluation of an Intensive Follow-up Protocol and Suggested Adaptations.  

PubMed

Ensuring retention in longitudinal studies of individuals with substance use disorders (SUD) is a continual challenge for researchers. This study made several modifications to a highly intensive follow-up protocol (Scott, 2004), originally designed for adults with SUD, in order to adapt it to a group of adolescents in low-intensity outpatient SUD treatment (N = 127, M age 16.7 yrs) and to accommodate limitations in the financial resources available for study staffing and transportation. In the present sample, adolescent participants generally found it unreasonable for study staff to request to contact people outside their immediate family in order to locate them and to attempt to schedule interviews 3-6 months in advance, as specified in the original protocol. Changes were made to accommodate these concerns and follow-up rates remained high (85-91%). Even though this study is limited by its non-experimental nature, it provides a replicable example of a scaled-down, less costly version of a highly intensive follow-up protocol that can be used to achieve high follow-up rates in studies of adolescents with SUD. We hope this will be encouraging for researchers and program evaluators who have limited resources or who work with participants who express concerns about privacy or study burden. PMID:24260012

Yeterian, Julie D; Dow, Sarah J; Kelly, John F

2012-09-01

245

Using Facebook to Maximize Follow-Up Response Rates in a Longitudinal Study of Adults Who Use Methamphetamine  

PubMed Central

This study examines the process and effects of using facebook (FB) to locate and re-contact study participants targeted for follow up in a longitudinal study of adult methamphetamine users (N = 649). A follow-up interview was conducted in 2009–11 approximately 8 years after previous study participation. Our paper describes re-contact efforts involving FB, including IRB regulatory issues and the effectiveness of using FB compared to mailings and phone calls. A total of 48 of the 551 surviving non-incarcerated participants who agreed to be contacted for follow up studies were contacted via FB, of whom 11 completed the follow-up interview. Those contacted through FB were more likely to be younger, female, relocated out-of-state, and reported somewhat higher rates of anxiety and cognitive problems compared to those not located on FB. Although participants contacted through FB are likely to differ demographically from those contacted by phone or mail, FB provides a potentially effective means to expand conventional methods of correspondence for contacting hard to reach participants. PMID:22879750

Bolanos, Franklin; Herbeck, Diane; Christou, Dayna; Lovinger, Katherine; Pham, Aurora; Raihan, Adnan; Rodriguez, Luz; Sheaff, Patricia; Brecht, Mary-Lynn

2012-01-01

246

A community-based follow-up study on diabetic retinopathy among type 2 diabetics in Kinmen  

Microsoft Academic Search

The purpose of this follow-up study was conducted to assess the incidence and risk factors of diabetic retinopathy (DR) among type 2 diabetics in Kinmen, Taiwan. A penal of eye screening regimes were performed yearly for 971 type 2 diabetics by two senior ophthalmologists using indirect ophthalmoscopy and 45-degree color fundus photography to examine fundus after dilating pupils from 1999

Tao-Hsin Tung; Shih-Jen Chen; Jorn-Hon Liu; Fenq-Lih Lee; An-Fei Li; Mong-Ping Shyong; Pesus Chou

2005-01-01

247

The Emerging Trend of EDP Auditing and the Implications for Collegiate Accounting Education: A 5-Year Follow-Up Study.  

ERIC Educational Resources Information Center

A five-year follow-up study compares the current business school curriculum content in electronic data processing and statistical sampling to the requirements of business. Differences still exist but there is evidence of progress by business schools in meeting the needs of business. (JOW)

Skudrna, Vincent J.; DiPillo, Pasquale J.

1988-01-01

248

Does Computer Coursework Transfer into Teaching Practice? A Follow-up Study of Teachers in a Computer Course.  

ERIC Educational Resources Information Center

Reports on a follow-up study of teachers in a course to meet certification requirements. Entry and exit questionnaires indicated that teachers' personal computer skills increased and that their integration of computers into instructional practice was extended by the course, which directly affected their outlook on technology use. (SM)

Keirns, Johanna

1992-01-01

249

A Follow-Up Study for Evaluation of the Preservice Secondary Science Teacher Education Program at The Ohio State University.  

ERIC Educational Resources Information Center

The purpose of this study was to follow up teacher graduates of a preservice field-based program after one to five years of teaching. Field-based activities in the program involved actual teaching for a period ranging from one to five quarters, organized at different levels--elementary, junior high, and senior high schools, and in different…

Swami, Piyush

250

Base Year, First, Second, and Third Follow-up. Data File Users Manual. Volume II. National Longitudinal Study.  

ERIC Educational Resources Information Center

This Users Manual is the supporting documentation for the Public Use Data File from the National Longitudinal Study of the High School Class of 1972 (NLS). The data file contains certain merged data from the base year (1972), and first, second, and third follow-up NLS surveys for 22,652 cases. This volume contains only appendices K through Q, as…

Levinsohn, Jay; And Others

251

The Development of a Culturally Fair Model for the Early Identification and Selection of Gifted Children: A Follow Up Study.  

ERIC Educational Resources Information Center

This paper presents the results of a study conducted as a follow-up to a joint project between the Flint Community Schools and the Educational Testing Service. In the project, a model for the identification and selection of gifted children was developed. The model sought to minimize the biases operating in more traditional identification…

Storlie, Theodore R.; And Others

252

Education Longitudinal Study of 2002: Base-Year to First Follow-Up Data File Documentation. NCES 2006-344  

ERIC Educational Resources Information Center

This report provides guidance and documentation for users of the public release for the combined base-year and first follow-up data of the Education Longitudinal Study of 2002 (ELS:2002). It provides extensive documentation of the content of the data files and how to access and manipulate them. Chapter 1 serves as an introduction to ELS:2002. It…

Ingels, Steven J.; Pratt, Daniel J.; Rogers, James E.; Siegel, Peter H.; Stutts, Ellen S.

2005-01-01

253

Third National Even Start Evaluation: Follow-Up Findings from the Experimental Design Study. NCEE 2005-3002  

ERIC Educational Resources Information Center

Citation: Ricciuti, A.E., R.G. St.Pierre, W. Lee, A. Parsad & T. Rimdzius. Third National Even Start Evaluation: Follow-Up Findings From the Experimental Design Study. U.S. Department of Education, Institute of Education Sciences, National Center for Education Evaluation and Regional Assistance. Washington, D.C., 2004. Background: The Even Start…

Ricciuti, Anne E., St.Pierre, Robert G.; Lee, Wang; Parsad, Amanda

2004-01-01

254

Reading, Metacognition and Motivation: A Follow-Up Study of German Students in Grades 7 and 8  

ERIC Educational Resources Information Center

This follow-up study to van Kraayenoord and Schneider (1999) examined the performance in reading, metacognition and motivation related to reading of students in Grades 7 and 8. Results showed significant correlations between all of the variables. A multivariate analysis of variance showed that "good" and "poor" readers differed in reading…

Roeschl-Heils, Annette; Schneider, Wolfgang; van Kraayenoord, Christina E.

2003-01-01

255

Morbidity and mortality in compensated cirrhosis type C: A retrospective follow-up study of 384 patients  

Microsoft Academic Search

BACKGROUND & AIMS: Few data are available concerning the long-term prognosis of chronic liver disease associated with hepatitis C virus infection. This study examined the morbidity and survival of patients with compensated cirrhosis type C.METHODS: A cohort of 384 European cirrhotic patients was enrolled at seven tertiary referral hospitals and followed up for a mean period of 5 years. Inclusion

G Fattovich; G Giustina; F Degos; F Tremolada; G Diodati; P Almasio; F Nevens; A Solinas; D Mura; JT Brouwer; H Thomas; C Njapoum; C Casarin; P Bonetti; P Fuschi; J Basho; A Tocco; A Bhalla; R Galassini; F Noventa; SW Schalm; G Realdi

1997-01-01

256

Life Satisfaction, Illness Behaviour, and Rehabilitation Outcome: Results of a One Year Follow-Up Study with Cardiac Patients.  

ERIC Educational Resources Information Center

Follow-up study one year after an inpatient cardiac rehabilitation program of 83 male cardiac patients found reported life satisfaction generally lower with increased physical complaints and emotional lability. Of patients originally identified as having high life satisfaction, 90 percent were back at work compared to 66 percent of patients with…

Myrtek, Michael

1987-01-01

257

The Cornella Health Interview Survey Follow-Up (CHIS.FU) Study: design, methods, and response rate  

PubMed Central

Background The aim of this report is to describe the main characteristics of the design, including response rates, of the Cornella Health Interview Survey Follow-up Study. Methods The original cohort consisted of 2,500 subjects (1,263 women and 1,237 men) interviewed as part of the 1994 Cornella Health Interview Study. A record linkage to update the address and vital status of the cohort members was carried out using, first a deterministic method, and secondly a probabilistic one, based on each subject's first name and surnames. Subsequently, we attempted to locate the cohort members to conduct the phone follow-up interviews. A pilot study was carried out to test the overall feasibility and to modify some procedures before the field work began. Results After record linkage, 2,468 (98.7%) subjects were successfully traced. Of these, 91 (3.6%) were deceased, 259 (10.3%) had moved to other towns, and 50 (2.0%) had neither renewed their last municipal census documents nor declared having moved. After using different strategies to track and to retain cohort members, we traced 92% of the CHIS participants. From them, 1,605 subjects answered the follow-up questionnaire. Conclusion The computerized record linkage maximized the success of the follow-up that was carried out 7 years after the baseline interview. The pilot study was useful to increase the efficiency in tracing and interviewing the respondents. PMID:12665430

Garcia, Montse; Schiaffino, Anna; Fernandez, Esteve; Marti, Merce; Salto, Esteve; Perez, Gloria; Peris, Merce; Borrell, Carme; Nieto, F Javier; Borras, Josep Maria

2003-01-01

258

Communication Development and Characteristics of Influencing Factors: A Follow-Up Study from 8 to 36 Months  

ERIC Educational Resources Information Center

In this follow-up study, we evaluated children's communication development at the ages of 8 ("n" ?= ?50), 18 ("n" ?=? 46), 24 ("n"? = ?44) and 36 months ("n"? = ?36) using the Finnish version of the "MacArthur Communicative Developmental Inventories" (MCDI). A sample of children ("n"? = ?14) received family-based intervention 10 times in five…

Haapsamo, Helena; Kuusikko-Gauffin, Sanna; Ebeling, Hanna; Larinen, Katja; Penninkilampi-Kerola, Varpu; Soini, Hannu; Moilanen, Irma

2013-01-01

259

The School of Technical Careers Baccalaureate Program: A Follow-Up Study of Graduates of 1974 and 1975.  

ERIC Educational Resources Information Center

A follow-up study of the first two graduating classes (1974 and 1975) of the School of Technical Careers (STC) Baccalaureate Program was conducted. Questionnaires were sent to eighty-seven graduates (of ninety) who had United States addresses on file. Questions pertained to current labor market status, current occupation, first job after…

Walsh, E. Michael; Reynolds, R. John

260

Adolescents With Gender Identity Disorder Who Were Accepted or Rejected for Sex Reassignment Surgery: A Prospective Follow-up Study  

Microsoft Academic Search

ObjectiveTo conduct a prospective follow-up study with 20 treated adolescent transsexuals to evaluate early sex reassignment, and with 21 nontreated and 6 delayed-treatment adolescents to evaluate the decisions not to allow them to start sex reassignment at all or at an early age.

YOLANDA L. S. SMITH; STEPHANIE H. M. VAN GOOZEN; PEGGY T. COHEN-KETTENIS

2001-01-01

261

Testing the Oregon delinquency model with 9-year follow-up of the Oregon Divorce Study.  

PubMed

This paper presents experimental tests of the Oregon delinquency model applied within a randomized design of an at-risk sample of single mothers and their elementary school-aged sons. In the theoretical model, ineffective parenting practices and deviant peer association serve as the primary mechanisms for growth in adolescent delinquent behavior and early arrests. Multiple-method assessments of 238 mothers and sons include delinquency as measured by teacher reports and official arrest records, parenting skills measured by observations of parent-child interactions, and deviant peer association as reported by focal boys. Analyses of the 9-year follow-up data indicate that the Oregon model of parent management training significantly reduced teacher-reported delinquency and police arrests for focal boys. As hypothesized, the experiments demonstrated that improving parenting practices and reducing contacts with deviant peers served as mediating mechanisms for reducing rates of adolescent delinquency. As predicted, there was also a significant delay in the timing of police arrests for youth in the experimental as compared to the control group. PMID:19338702

Forgatch, Marion S; Patterson, Gerald R; Degarmo, David S; Beldavs, Zintars G

2009-01-01

262

Dementia nurses' experience of the Mental Capacity Act 2005: a follow-up study.  

PubMed

Specialist community dementia nurses are an appropriate sample to investigate longer-term decision-making and end-of-life care planning. Implemented in 2007, the Mental Capacity Act (MCA) provides opportunities for assisting with planning and making decisions on others' behalf, and may be expected to be entrenched within clinical practice. We conducted follow-up qualitative interviews with 15 community-based dementia nurses to detect changes and developments in views and practices of the MCA. Thematic analysis identified recurrent themes and developed into a coding framework. At Time2, there was greater awareness of general and specific principles of MCA and greater confidence in using it. There was greater involvement in discussing planning finances, less so in end-of-life-care. Some participants were concerned about lack of understanding amongst other professionals and felt more public awareness was required. Supplementary training, opportunities for mentoring and supervision may develop greater confidence among dementia practitioners and support their roles in informing and advising people with dementia and carers. PMID:24381044

Manthorpe, Jill; Samsi, Kritika; Rapaport, Joan

2014-01-01

263

Neuropsychological functioning and social anhedonia: Three-year follow-up data from a longitudinal community high risk study  

PubMed Central

Social anhedonia is a promising vulnerability marker for schizophrenia-spectrum pathology. Prior research has demonstrated that individuals with psychometrically-defined social anhedonia show a range of “schizophrenia-like” neurocognitive abnormalities. However, this research is limited in that it is based largely on the study of college students. The present article reports findings from a longitudinal study of social anhedonia recruited from a community sample. As part of this study, a neurocognitive battery was administered at baseline and at three-year follow-up sessions to participants with (n = 78) vs. without (n = 77) social anhedonia. Additional measures of global functioning and schizotypal, schizoid and paranoid schizophrenia-spectrum symptoms were also administered. Across groups, subjects showed significant improvement in neurocognitive functioning over time. Compared to controls, at follow-up, individuals with social anhedonia showed significantly poorer attentional vigilance and simple processing speed, but failed to evidence impairments in immediate or delayed verbal memory, immediate or delayed visual memory, visual or verbal working memory, olfaction or executive abilities. At follow-up, within the social anhedonia group, schizoid (and to a lesser extent, schizotypal) symptom severity was associated with a range of neurocognitive impairments. Neurocognitive impairments were generally not associated with paranoid symptoms or global functioning. Baseline neurocognitive performance was not significantly predictive of follow-up symptom severity or functioning. Collectively, these findings suggest that neurocognitive dysfunctions only characterize a subset of individuals with social anhedonia. PMID:22507637

Cohen, Alex S.; Couture, Shannon M.; Blanchard, Jack J.

2012-01-01

264

Barriers and facilitators for participation in health promotion programs among employees: a six-month follow-up study  

PubMed Central

Background Health promotion programs (HPPs) are thought to improve health behavior and health, and their effectiveness is increasingly being studied. However, participation in HPPs is usually modest and effect sizes are often small. This study aims to (1) gain insight into the degree of participation of employees in HPPs, and (2) identify factors among employees that are associated with both their intention to participate and actual participation in HPPs. Methods Employees of two organizations were invited to participate in a six-month follow-up study (n?=?744). Using questionnaires, information on participation in HPPs was collected in two categories: employees’ intention at baseline to participate and their actual participation in a HPP during the follow-up period. The following potential determinants were assessed at baseline: social-cognitive factors, perceived barriers and facilitators, beliefs about health at work, health behaviors, and self-perceived health. Logistic regression analyses, adjusted for demographics and organization, were used to examine associations between potential determinants and intention to participate, and to examine the effect of these determinants on actual participation during follow-up. Results At baseline, 195 employees (26%) expressed a positive intention towards participation in a HPP. During six months of follow-up, 83 employees (11%) actually participated. Participants positively inclined at baseline to participate in a HPP were more likely to actually participate (OR = 3.02, 95% CI: 1.88-4.83). Privacy-related barriers, facilitators, beliefs about health at work, social-cognitive factors, and poor self-perceived health status were significantly associated with intention to participate. The odds of employees actually participating in a HPP were higher among participants who at baseline perceived participation to be expected by their colleagues and supervisor (OR = 2.87, 95% CI: 1.17-7.02) and among those who said they found participation important (OR = 2.81, 95% CI: 1.76-4.49). Conclusions Participation in HPPs among employees is limited. Intention to participate predicted actual participation in a HPP after six months of follow-up. However, only 21% of employees with a positive intention actually participated during follow-up. Barriers, facilitators, beliefs about health at work, social-cognitive factors, and a poor self-perceived health status were associated with intention to participate, but hardly influenced actual participation during follow-up. PMID:24909151

2014-01-01

265

Characteristics associated with intervention and follow-up attendance in a secondhand smoke exposure study for families of NICU infants.  

PubMed

Abstract Objective: The neonatal intensive care unit (NICU) is an ideal setting to intervene with an under served population on secondhand smoke exposure (SHSe). Unfortunately, attrition may compromise outcomes. Baseline characteristics associated with intervention and follow-up attendance were investigated in mothers who participated in a novel SHSe prevention study designed for households with a smoker and a NICU-admitted infant. Methods: Intervention participants received two motivational, NICU-based counseling sessions; usual care participants received pamphlets. Home-based follow-up assessments occurred at 1, 3 and 6 months. Sociodemographic, smoking history, and psychosocial factors were analyzed. Results: Mothers from households with greater numbers of cigarettes smoked and fewer children had higher odds of both intervention and follow-up attendance. Maternal smoking abstinence (lifetime), more adults in the home and higher perceived interpersonal support were also associated with higher odds of follow-up visit completion. Conclusions: Innovative strategies are needed to engage mothers in secondhand smoke interventions, especially mothers who smoke, have lower levels of social support and have greater childcare responsibilities. PMID:25053191

Northrup, Thomas F; Green, Charles; Evans, Patricia W; Stotts, Angela L

2014-08-14

266

Radiation therapy of penile cancer: six to ten-year follow-up  

SciTech Connect

Ten patients with penile cancer were treated with radiation therapy between 1968 and 1973. Nine of ten remain free of disease though in 1 patient a new penile primary developed eight years after the radiation therapy and was treated by partial penectomy. One patient died following surgery for ''bleeding ulcer.'' He was free of penile cancer five years after radiation. The most common complication is urethral stricture and skin telangiectasia.

Grabstald, H.; Kelley, C.D.

1980-06-01

267

EMCS (Energy Monitoring and Control Systems) Installation Follow-Up study. Volume I. Final report April 1983March 1984  

Microsoft Academic Search

This report provides the Task 3 deliverables for an EMCS Installation Follow-Up study. The objective of this study is to provide data on experience at existing EMCS installations for use in developing guidelines for better implementation of EMCS. Section 2.0 of this report provides a list of probable causes for EMCS success\\/failure identified in previous studies. Section 3.0 discusses whether

Bruning

1984-01-01

268

Family burden and coping strategies in schizophrenia: 1-year follow-up data from the BIOMED I study  

Microsoft Academic Search

Background: To date, only few data are available on how family burden in schizophrenia changes over time. In addition, no study has\\u000a explored how such factors as coping styles and social support influence burden over time. This paper presents the 1-year follow-up\\u000a data from the BIOMED I study on family burden and coping strategies in schizophrenia. Methods: A sample of

L. Magliano; G. Fadden; M. Economou; T. Held; M. Xavier; M. Guarneri; C. Malangone; C. Marasco; M. Maj

2000-01-01

269

Development of diastolic heart failure in a 6-year follow-up study in patients after acute myocarditis  

Microsoft Academic Search

BackgroundThe aim of this study was to analyse the long-term prognosis of patients with acute myocarditis (AMC) who had been discharged from hospital while having normal left ventricular (LV) function.Methods and results50 patients with acute myocarditis who underwent endomyocardial biopsies (EMBs) were prospectively studied. Their clinical condition was examined during a mean follow-up period of 72 (54–78) months, including tissue

Felicitas Escher; Dirk Westermann; Regina Gaub; Johannes Pronk; Thomas Bock; Nidal Al-Saadi; Uwe Kühl; Heinz-Peter Schultheiss; Carsten Tschöpe

2010-01-01

270

Intimal hyperplasia thickness at follow-up is independent of stent size: A serial intravascular ultrasound study  

Microsoft Academic Search

The purpose of this study was to determine whether the thickness of the intimal hyperplasia (IH) layer that accumulates within Palmaz-Schatz stents is dependent on stent size. Intravascular ultrasound (IVUS) and quantitative angiographic (QCA) studies were performed after stent implantation and at follow-up (5.4 ± 3.8 months) in 161 patients with 177 lesions treated with 221 Palmaz-Schatz stents. Stent and

Rainer Hoffmann; Gary S. Mintz; Augusto D. Pichard; Kenneth M. Kent; Lowell F. Satler; Martin B. Leon

1998-01-01

271

Parental Subfecundity and Risk of Decreased Semen Quality in the Male Offspring: A Follow-up Study  

Microsoft Academic Search

A few studies have found poor semen quality in sons whose mothers have received fertility treatment, but it is unknown whether the poor semen quality is related to the infertility treatment or to infertility per se, for example, whether it is caused by hereditable factors. Using data from a population-based, Danish follow-up study con- ducted in 2005-2006, the authors of

C. H. Ramlau-Hansen; A. M. Thulstrup; J. Olsen; J. P. Bonde

2008-01-01

272

Service Utilization and Cost of Community Care for Discharged State Hospital Patients: A 3Year Follow-Up Study  

Microsoft Academic Search

Objective: This study examined the mental health service utilization and costs of 321 discharged state hospital patients during a 3-year follow-up period compared with costs if the patients had remained in the hospital. Method: The study subjects were long-stay pa- tients discharged from Philadelphia State Hospital after 1988. A longitudinal integrated da- tabase on all mental health and medical services

Aileen B. Rothbard; Eri Kuno; Arie P. Schinnar; Trevor R. Hadley; Roland Turk

273

Early Risk Factors for Depressive Symptoms among Korean Adolescents: A 6-to-8 Year Follow-up Study  

PubMed Central

Depression during adolescence is critical to the individual's own development. Hence, identifying individuals with high-risk depression at an early stage is necessary. This study aimed to identify childhood emotional and behavioral risk factors related to depressive symptoms in Korean adolescents through a longitudinal study. The first survey took place from 1998 to 2000, and a follow-up assessment conducted in 2006, as the original participants reached 13-15 yr of age. The first assessment used the Korean version of Child Behavior Checklist and a general questionnaire on family structure, parental education, and economic status to evaluate the participants. The follow-up assessment administered the Korean Children's Depression Inventory. Multiple regression analysis revealed that childhood attention problems predicted depressive symptoms during adolescence for both boys and girls. For boys, family structure also predicted adolescent depressive symptoms. This study suggests that adolescents with attention problems during childhood are more likely to experience depressive symptoms. PMID:24265533

Shin, Kyoung Min; Shin, Yun Mi; Park, Kyung Soon

2013-01-01

274

Work-Related Musculoskeletal Disorders in Physical Therapists: A Prospective Cohort Study With 1-Year Follow-up  

PubMed Central

Background: Work-related musculoskeletal disorders (WMSDs) have a significant impact on physical therapists, but few studies have addressed the issue. Research is needed to determine the scope of the problem and the effects of specific risk factors. Objectives: The objectives of this study were: (1) to determine the 1-year incidence rate of WMSDs in physical therapists and (2) to determine the effects of specific risk factors. Design: This was a prospective cohort study with 1-year follow-up. Methods: Subjects were randomly selected American Physical Therapy Association members (N=882). Exposure assessment included demographic data, physical risk factors, job strain, and specific physical therapy tasks. The primary outcome was WMSDs, with a severity rating of at least 4/10 and present at least once a month or lasting longer than a week. Results: The response rate to the baseline questionnaire was 67%. Ninety-three percent of the subjects who responded to the baseline questionnaire responded to the follow-up questionnaire. The 1-year incidence rate of WMSDs was 20.7%. Factors that increased the risk for WMSDs included patient transfers, patient repositioning, bent or twisted postures, joint mobilization, soft tissue work, and job strain. Limitations: The primary limitation of this study was the number of therapists who had a change in their job situation during the follow-up year. Conclusions: Work-related musculoskeletal disorders are prevalent in physical therapists. Physical therapy exposures, patient handling, and manual therapy, in particular, increase the risk for WMSDs. PMID:18276935

Campo, Marc; Weiser, Sherri; Koenig, Karen L; Nordin, Margareta

2008-01-01

275

Long-term follow-up of patients with persistent\\/recurrent, isolated haematuria: A Hungarian multicentre study  

Microsoft Academic Search

A retrospective multicentre study of 341 children with persistent\\/recurrent, isolated haematuria is described. The haematuria was isolated for at least 6 months at the beginning of observation. The duration of follow-up was 2–5 years in 201, 5–10 years in 119, 10–15 years in 19, and over 15 years in 2 cases. Of these patients 47.8% became symptom-free. In 18.4% the

S. Túri; M. Visy; Á. Vissy; V. Jfiszai; Zs. Czirbesz; I. Haszon; Zs. Szelid; I. Ferkis

1989-01-01

276

Follow-Up Studies on Epstein – Barr virus IgA\\/VCA Antibody-Positive Persons in Zangwu County, China  

Microsoft Academic Search

Summary Serological mass surveys were carried out in Zangwu County, China, using an immunoenzymatic test. 3,533 persons were found to have Epstein-Barr virus (EBV) IgA\\/VCA antibody among 148,029 persons age 30 years and older who were tested during 1978–1980. Among the IgA\\/VCA antibody-positive persons, 55 nasopharyngeal carcinoma (NPC) cases were detected. Follow-up studies were carried out yearly on the IgA\\/VCA

Y. Zeng; J. M. Zhong; L. Y. Li; P. Z. Wang; H. Tang; Y. R. Ma; J. S. Zhu; W. J. Pan; Y. X. Liu; Z. N. Wei; J. Y. Chen; Y. K. Mo; E. J. Li; B. F. Tan

1983-01-01

277

Reduction in Fine Particulate Air Pollution and Mortality Extended Follow-up of the Harvard Six Cities Study  

Microsoft Academic Search

Rationale: A large body of epidemiologic literature has found an association of increased fine particulate air pollution (PM2.5) with acute and chronic mortality. The effect of improvements in particle exposure is less clear. Objectives: Earlier analysis of the Harvard Six Cities adult cohort study showed an association between long-term ambient PM2.5 and mortality between enrollment in the mid-1970s and follow-up

Francine Laden; Joel Schwartz; Frank E. Speizer; Douglas W. Dockery

278

Dysfunctional Attitudes and Early Maladaptive Schemas as Predictors of Depression: A 9Year Follow-Up Study  

Microsoft Academic Search

The Dysfunctional Attitude Scale (DAS) and the Young Schema Questionnaire (YSQ) have been suggested as vulnerability markers\\u000a for depression and entrenched psychological disorders, respectively. One-hundred-and-fifteen clinically depressed (CDs), previously\\u000a depressed (PDs), and never depressed individuals completed the DAS, the YSQ, and the Beck Depression Inventory in the index\\u000a study, and were followed up 9 years later in relation to diagnostic status,

Marianne Halvorsen; Catharina E. Wang; Martin Eisemann; Knut Waterloo

2010-01-01

279

Stability of dysfunctional attitudes and early maladaptive schemas: A 9-year follow-up study of clinically depressed subjects  

Microsoft Academic Search

The Dysfunctional Attitude Scale (DAS) and the Young Schema Questionnaire (YSQ) have been suggested as relatively stable vulnerability markers for depression and entrenched psychological disorders, respectively. One-hundred-and-forty-nine clinically depressed (CDs), previously depressed (PDs) and never-depressed subjects (NDs) completed the DAS, the YSQ and the Beck Depression Inventory in the index study and were followed-up nine years later. Results showed: (1)

Catharina E. A. Wang; Marianne Halvorsen; Martin Eisemann; Knut Waterloo

2010-01-01

280

Self-Determination and Positive Adult Outcomes: A Follow-Up Study of Youth with Mental Retardation or Learning Disabilities  

Microsoft Academic Search

There is increased emphasis on self -determination as an important outcome for youth with disabilities if they are to achieve positive adult outcomes after they leave school. However, the causal link between self-determination and positive adult outcomes has remained untested. The Arc conducted a follow-up study of students with mental retardation or learning disabilities for whom data regarding self-determination had

MICHAEL WEHMEYER; MICHELLE SCHWARTZ

281

Risk factors for myocardial infarction and death in newly detected NIDDM: the Diabetes Intervention Study, 11-year follow-up  

Microsoft Academic Search

Summary   The Diabetes Intervention Study (DIS) is a prospective population-based multicentre trial of newly detected cases of non-insulin-dependent\\u000a diabetes mellitus (NIDDM). This report analyses the risk factors for subsequent coronary heart disease and all-cause death\\u000a during the 11-year follow-up. The prognostic significance of the categories of the NIDDM Policy Group was validated with respect\\u000a to the incidence of coronary heart

M. Hanefeld; S. Fischer; U. Julius; J. Schulze; U. Schwanebeck; H. Schmechel; H. J. Ziegelasch; J. Lindner

1996-01-01

282

A Fifty Year Mortality Follow-up Study of Veterans Exposed to Low Level Chemical Warfare Agent, Mustard Gas  

Microsoft Academic Search

PURPOSE: To determine if there is an increased risk of any cause specific mortality associated with low level mustard gas exposure among World War II Navy veterans.METHODS: A retrospective mortality follow-up study was conducted comparing the mortality of World War II Navy veterans who received low-level non-lethal exposures of mustard gas to that of World War II Navy veterans who

Tim Bullman; Han Kang

2000-01-01

283

Homeopathic treatment of patients with chronic sinusitis: A prospective observational study with 8 years follow-up  

Microsoft Academic Search

BACKGROUND: An evaluation of homeopathic treatment and the outcomes in patients suffering from sinusitis for ?12 weeks in a usual care situation. METHODS: Subgroup analysis including all patients with chronic sinusitis (ICD-9: 473.9; ?12 weeks duration) of a large prospective multicentre observational study population. Consecutive patients presenting for homeopathic treatment were followed-up for 2 years, and complaint severity, health-related quality

Claudia M Witt; Rainer Lüdtke; Stefan N Willich

2009-01-01

284

Depression and Suicidal Ideation After Predictive Testing for Huntington's Disease: A Two-Year Follow-up Study  

Microsoft Academic Search

The present study reports a two-year follow-up of psychological effects of predictive testing for Huntington's disease. Questionnaires assessing depression, general health, well-being, self injurious behavior, life satisfaction, and lifestyle were completed by 35 carriers and 58 non-carriers before the predictive test, and 2, 6, 12, and 24 months afterwards. Both carriers and non-carriers showed high suicidal ideation before the predictive

Maria U. Larsson; Mary A. Luszcz; Tarja-Brita Robins Wahlin

2006-01-01

285

Obsessive–compulsive disorder: A 3-year prospective follow-up study of patients treated with serotonin reuptake inhibitors  

Microsoft Academic Search

This study aimed to evaluate the long-term course of obsessive–compulsive disorder (OCD) in patients treated with serotonin reuptake inhibitors (SRIs) and to identify predictors of clinical outcome. Seventy-nine patients fulfilling DSM-IV criteria for OCD were followed prospectively for 3 years. Baseline information was collected on demographic and clinical characteristics, using standardized instruments. During the follow-up period, the clinical status of

Francesco Catapano; Francesco Perris; Mariangela Masella; Flavia Rossano; Marco Cigliano; Lorenza Magliano; Mario Maj

2006-01-01

286

[Level of smoking of 3rd and 4th grade students studying health and related factors: follow-up study].  

PubMed

The levels of smoking of 1st and 2nd year students at Faculty of Medicine and Manisa School of Health at Celal Bayar University were investigated in 2006-2007. This study is carried out in order to see if there is a change in the same students' level of smoking while they are in 3rd and 4th year. In addition, the study aimed to examine the factors affecting the level of use and attitudes towards the law effectuated in July 19, 2009. This is a follow-up study with 80.42% return rate. A 26-item structured questionnaire was administered. The participants filled out the questionnaires under supervision of the researchers in their classrooms. The University Institutional Review Board approved the study. The total of participants (263) of the follow-up study included 189 female and 74 male. The rate of experimenting with smoking was 49% with the mean age of 15.7 (SD= 4.01 years). The mean age of experimenting with smoking was the earliest on male students studying at faculty of medicine. The level of smoking was found to be the most on females, studying at faculty of medicine and staying at the dormitory, with smoking parents (p< 0.05). The most important reason to begin smoking was curiosity (55.2%) while bad breath and yellowing of teeth were the reasons to quit (91.7%). 83.3% of the students thought that the law will be effective on quit smoking. The level of both experimenting and use of smoking has been increased over time. It is suggested that medical students' awareness about the danger of smoking should be raised at earlier grades. In addition, lectures should be offered to students at School of Health and they should be encouraged to unite in order to fight with smoking. PMID:22233305

Göktalay, Tu?ba; Cengiz Özyurt, Beyhan; Sakar Co?kun, Ay?in; Celik, Pinar

2011-01-01

287

Changes in quality of life among Norwegian school children: a six-month follow-up study  

PubMed Central

Background A considerable gap exists in regard to longitudinal research on quality of life (QoL) in community populations of children and adolescents. Changes and stability of QoL have been poorly examined, despite the fact that children and adolescents undergo profound developmental changes. The aims of the study were to investigate short-term changes in student QoL with regard to sex and age in a school-based sample. Methods A representative Norwegian sample of 1,821 school children, aged 8–16 years and their parents were tested at baseline and 6 months later, using the Inventory of Life Quality for Children and Adolescents (ILC) and the Kinder Lebensqualität Fragebogen (KINDL). Student response rate at baseline was 71.2% and attrition over the follow-up period was 4.6%, and 1,336 parents (70%) completed the follow-up. Change scores between baseline and follow-up evaluations were analysed by means of ANCOVA in regard to sex and age effects. Results Students in the 8th grade reported a decrease in QoL over the six-month follow-up period as compared to those in the 6th grade with regard to Family and School domains and total QoL on the KINDL. For emotional well-being a significant linear decrease in QoL across grades 6th to 10th was observed. However, student ratings on the Friends and Self-esteem domains did not change significantly by age. Girls reported a higher decrease in their QoL across all grades over the follow-up period than did boys in respect of Self-esteem on the KINDL, and an age-related decrease in total QoL between 6th and 8th grade on the ILC. Parent reports of changes in child QoL were nonsignificant on most of the domains. Conclusion The observed age and sex-related changes in school children's QoL across the six-month follow-up period should be considered in epidemiological as well as clinical research. PMID:19193211

Jozefiak, Thomas; Larsson, Bo; Wichstrøm, Lars

2009-01-01

288

Level of suicidal intent predicts overall mortality and suicide after attempted suicide: a 12-year follow-up study  

PubMed Central

Background The aim of this study was to comprehensively examine clinical risk factors, including suicide intent and hopelessness, for suicide and risk of death from all causes after attempted suicide over a 12-year follow-up period. Methods A systematic sample of 224 patients from consecutive cases of attempted suicide referred to health care in four Finnish cities between 1 January and 31 July 1990 was interviewed. Results After 12 years of follow-up 22% of these patients had died, 8% by committing suicide. The only statistically significant risk factor for eventual suicide was high scores on Beck's Suicidal Intention Scale. Male gender, older age, physical illness or disability and high scores on Beck's Suicidal Intention Scale predicted death overall. Conclusions Following attempted suicide, high intention to kill oneself is a significant risk factor for both death from all causes and suicide. PMID:15099401

Suominen, Kirsi; Isometsä, Erkki; Ostamo, Aini; Lönnqvist, Jouko

2004-01-01

289

Loss to follow-up occurs at all stages in the diagnostic and follow-up period among HIV-infected patients in Guinea-Bissau: a 7-year retrospective cohort study  

PubMed Central

Objectives To describe loss to follow-up (LTFU) at all stages of the HIV programme. Design A retrospective cohort study. Setting The HIV clinic at Hospital National Simão Mendes in Bissau, Guinea-Bissau. Participants A total of 4080 HIV-infected patients. Outcome measures Baseline characteristics, percentages and incidence rates of LTFU as well as LTFU risk factors at four different stages: immediately after HIV diagnosis (stage 1), after the first CD4 cell count and before a follow-up consultation (stage 2), after a follow-up consultation for patients not eligible for antiretroviral treatment (ART; stage 3) and LTFU among patients on ART (stage 4). Results Almost one-third of the patients were lost to the programme before the first consultation where ART initiation is decided; during the 7-year observation period, more than half of the patients had been lost to follow-up (overall incidence rate=51.1 patients lost per 100 person-years). Age below 30?years at inclusion was a risk factor for LTFU at all stages of the HIV programme. The biggest risk factors were body mass index <18.5?kg/m2 (stage 1), male gender (stage 2), HIV-2 infection (stage 3) and CD4 cell count <200 cells/?L (stage 4). Conclusions In this study, LTFU constituted a major problem, and this may apply to other similar ART facilities. More than half of the patients were lost to follow-up shortly after enrolment, possibly implying a high mortality. Thus, retention should be given a high priority. PMID:24163204

Hønge, Bo Langhoff; Jespersen, Sanne; Nordentoft, Pernille Bejer; Medina, Candida; da Silva, David; da Silva, Zacarias José; Østergaard, Lars; Laursen, Alex Lund; Wejse, Christian

2013-01-01

290

The siblings of childhood cancer patients need early support: a follow up study over the first year  

PubMed Central

Background and methods: In a 1 year follow up study, we assessed the life situation of 33 siblings of childhood cancer patients and 357 healthy controls. The hypothesis was that siblings have more behavioural and health related problems just after the cancer diagnosis. Validated assessment methods were used. Results: Siblings below school age tended to have conduct problems, psychosomatic problems, and a mixed group of other behavioural problems, when assessed 3 months after the cancer diagnosis. These symptoms became less evident during follow up. Among the school aged siblings, however, conduct problems, learning problems, psychosomatic problems, impulsive-hyperactive symptoms, and other behavioural symptoms remained unchanged during follow up. In their self assessments, the school aged siblings showed both state and trait anxiety more often than controls at the first assessment, but later these symptoms settled to the same level as the controls. The overall Children's Depression Inventory (CDI) depression scores did not show differences between the study groups. Conclusions: The ratings of the parents were in keeping with the self assessment of the school aged siblings only in a few aspects; the emphasis of findings can be changed when proxies are used. The siblings have symptoms and adverse feelings which probably could be relieved by targeted, early information about the illness, and possibly by group discussions or activities, soon after the cancer diagnosis. In order to obtain necessary support for the siblings with educational problems, school personnel need to be informed about the sibling distress. PMID:15499052

Lahteenmaki, P; Sjoblom, J; Korhonen, T; Salmi, T

2004-01-01

291

Functional disability in medication management and driving among individuals with HIV: A 1-year follow-up study  

PubMed Central

Approximately 50% of individuals with HIV report cognitive deficits that can affect social or occupational functioning. The present study used a longitudinal design (1 year) to examine the relationship between cognitive factors and incidental functional deficits in medication management and driving ability among a cohort of 101 HIV+ participants. Participants were classified into groups of functionally “stable” and “disabled” for each laboratory-based functional task (i.e., Medication Management Task–Revised, MMT–R, and PC-based driving simulator). We hypothesized that participants who exhibited a functional deficit in either MMT–R or driving at follow-up assessment would demonstrate significantly poorer baseline cognitive performance at study entry than participants who remained functionally stable. As hypothesized, participants who demonstrated significantly lower baseline performance in learning/memory and executive functioning also demonstrated functional disability on the MMT–R at follow-up when compared to functionally stable participants. Poor baseline performance in speed of information processing was associated with a deficit in driving ability at follow-up assessment. Our results suggest that lower baseline cognitive functioning predicts downstream functional disability, and that deficits in learning/memory and information processing speed are particularly predictive of deficits in medication management and driving ability. PMID:23237014

Thames, April D.; Arentoft, Alyssa; Rivera-Mindt, Monica; Hinkin, Charles H.

2013-01-01

292

MMPI-2 personality profiles and suicidal ideation and behavior in victims of bullying at work: a follow-up study.  

PubMed

The main aim of this study was to investigate longitudinally the personality profile and suicidal ideation and behavior in victims of bullying at work in relation to the evolution of the victimization. Forty-eight victims were evaluated by means of medical and psychological assessment including the Minnesota Multiphasic Personality Inventory-2 (MMPI-2). A follow up session was carried out after an average of 22 months. At first evaluation, the average MMPI-2 personality profile of victims showed abnormal elevations on scales Hs (Hypochondria), D (Depression), Hy (Hysteria), and Pa (Paranoia), which were strikingly similar to that found in previous studies. Furthermore, suicidal ideation and behavior were common among victims. At follow-up, 26 victims reported that the degree of bullying had remained the same or had even worsened, whereas 22 said that the situation had improved or had been resolved. Although there was a trend toward normalization in the MMPI-2 profile for all victims, the profile of the "static" group was still abnormal at follow up. On the contrary, the profile of the "improved" group was entirely within normal range. Suicidal ideation and behavior decreased in all victims, but only to a significant degree in the improved group. Results are discussed in the light of the bullying process. PMID:24547677

Romeo, Luciano; Balducci, Cristian; Quintarelli, Emanuele; Riolfi, Andrea; Pelizza, Luisa; Serpelloni, Andrea; Tisato, Silvia; Perbellini, Luigi

2013-01-01

293

Cementation of cross-linked polyethylene liner into well-fixed acetabular shells: mean 6-year follow-up study.  

PubMed

The purpose of this study was to evaluate retrospectively the outcomes of cementation of cross-linked polyethylene (PE) liner in a well-fixed metal shell in 23 hips with an average follow-up period of 6 years. The mean Harris hip score was 69.6 +/- 12 (range, 46-83) points preoperatively. The average postoperative follow-up was 72.3 months (range, 56-100 months). At the final follow-up, the mean Harris hip score was 95.5 +/- 3 (84-100) points. There was no change in the bone-shell interface. No new osteolytic lesions were identified. The lesions impacted with bone graft had united completely. The remaining osteolytic lesions had decreased in size. There was no recurrent osteolysis, hip dislocation, component migration, and failure at the cement-metal interface. The results of the current study revealed that cementation of cross-linked PE liner into a well-fixed shell provided good midterm durability. PMID:20347715

Wang, Jung-Pan; Chen, Wei-Ming; Chen, Cheng-Fong; Chiang, Chao-Ching; Huang, Ching-Kuei; Chen, Tain-Hsiung

2010-04-01

294

A Follow-up Study on U.S.-Trained Iranian Faculty Members: Satisfactions and Dissatisfactions  

ERIC Educational Resources Information Center

Iran was one of the major contributors to the international student population in the United States. For some years, the number of Iranian students studied in America mounted such that there were more Iranians studying at colleges and universities in the United States than from any other foreign country. This study examined the satisfaction of…

Arasteh, Hamidreza

2009-01-01

295

Neurocognitive and social functioning in schizophrenia: a 2.5 year follow-up study  

Microsoft Academic Search

In our previous study we demonstrated that, in 80 schizophrenia subjects, verbal ability, verbal memory and executive functioning were significantly associated with social problem solving. The objective of this present study was to assess the longitudinal stability of the relationship between social and neurocognitive functioning in schizophrenia. This 2.5year longitudinal cohort study re-assessed community functioning, social problem solving and symptoms

Jean Addington; Donald Addington

2000-01-01

296

Predicting outcome in patients with chronic stroke: findings of a 3-year follow-up study  

Microsoft Academic Search

This thesis is based on the findings of the FuPro-Stroke study (the Stroke section of the Functional Prognostification and disability study on neurological disorders), which is a multicentre, prospective cohort study among patients with stroke, who were included during inpatient rehabilitation. The aim of the research reported on in the present thesis was to investigate the long-term prognosis of chronic

I. G. L. van de Port

2006-01-01

297

Persistent asthma due to isocyanates. A follow-up study of subjects with occupational asthma due to toluene diisocyanate (TDI)  

SciTech Connect

Thirty-five subjects with occupational asthma due to toluene diisocyanate (TDI) exposure were examined. All the subjects were studied with inhalation challenges with TDI and with methacholine. TDI asthma was documented by a positive inhalation challenge to low levels of TDI. Airway responsiveness to methacholine was in the range of asthmatic patients at the time of diagnosis. After an average follow-up interval of 10 months, all the subjects were re-examined. Of the 35 subjects examined, 30 subjects (85.7%) left the workplace, and 5 remained in the same job. Twenty-seven subjects (77.1%) continued to have asthmatic attacks requiring medication for relief of symptoms. At follow-up examination, TDI asthma was documented by a positive inhalation challenge to TDI in 27 subjects. Of these 27 TDI reactors, 22 subjects were removed from occupational exposure to TDI. The TDI reactors had persistent respiratory symptoms and airway hyperresponsiveness to methacholine. At follow-up visit, 8 subjects (22.9%) lost sensitization to TDI; 5 subjects (62.5%) in this group had also normal airway responsiveness to methacholine after removal from exposure. Only 1 subject among the TDI nonreactors complained of mild respiratory symptoms. At diagnosis, there were no significant differences between subjects who recovered and those who did not with regard to age, smoking habits, atopy, duration of exposure to isocyanates, duration of symptoms, baseline FEV1 (% pred), and baseline airway responsiveness to methacholine.

Mapp, C.E.; Corona, P.C.; De Marzo, N.; Fabbri, L.

1988-06-01

298

Gender differences in outcomes in people with schizophrenia in rural China: 14-year follow-up study.  

PubMed

Background Little is known about gender differences in the long-term outcomes of people with schizophrenia living in the community. Aims To explore gender differences in the 14-year outcome of people with schizophrenia in rural China. Method A 14-year follow-up study among a 1994 cohort (n = 510) of participants with schizophrenia was conducted in Xinjin County, Chengdu, China. All participants and their informants were followed up in 2004 and 2008 using the Patients Follow-up Schedule. Results Compared with female participants, male participants were significantly younger, had significantly higher rates of mortality, suicide and homelessness, and poorer family and social support. There was no significant gender difference in Positive and Negative Syndrome Scale scores, previous suicide attempts, those never treated, previous hospital admission or inability to work. Longer duration of illness was associated with functional decline and comparatively poorer family economic status. Conclusions The long-term outcomes of men with schizophrenia is worse than those of women with the disorder in rural China. Higher mortality, suicide and homelessness rates in men may contribute partly to the higher prevalence of schizophrenia in women in China. Policies on social and family support and gender-specific intervention strategies for improving long-term outcomes should be developed for people with this disorder. PMID:25573398

Ran, Mao-Sheng; Mao, Wen-Jun; Chan, Cecilia Lai-Wan; Chen, Eric Yu-Hai; Conwell, Yeates

2015-04-01

299

ACCELERATION AND ENRICHMENT IN THE JUNIOR HIGH SCHOOL. A FOLLOW-UP STUDY.  

ERIC Educational Resources Information Center

THE 1963-64 STUDY INVOLVED AN INVESTIGATION OF ACCELERATION IN MATHEMATICS AND ENRICHMENT IN READING AND SCIENCE IN THE JUNIOR HIGH SCHOOL. BUT THE RESEARCH WAS BROADENED AND, UNLIKE THE 1962-63 STUDY, EXPLORED MORE DEEPLY THE EFFECTS OF ACCELERATION AND ENRICHMENT. A NUMBER OF SCHOOLS OUTSIDE OF WALLA WALLA WAS USED. PROBLEMS CONSIDERED WERE--(1)…

ARENDS, RICHARD H.; FORD, PAUL M.

300

Baccalaureate and Beyond Longitudinal Study: 1993/94 First Follow-Up Methodology Report. Technical Report.  

ERIC Educational Resources Information Center

The Baccalaureate and Beyond Longitudinal Study (B&B:93) tracks the experiences of a cohort of recent college graduates, those who received the baccalaureate degree during the 1992-93 academic year and were first interviewed as part of the National Postsecondary Student Aid Study. The experiences of this group in the areas of academic enrollment,…

Green, Patricia J.; And Others

301

Students' Thinking and Alternative Conceptions of Transport Systems in Plants: A Follow-Up Study  

ERIC Educational Resources Information Center

The purpose of the study was to explore students' alternative conceptions and their associative thinking regarding internal transport in plants through administration of a refined diagnostic test. Questions of associative thinking and explanation were added to form a third tier of the previous two-tier test. The study found three terms related to…

Wang, Jing-Ru

2007-01-01

302

Temporal stability of antisocial personality disorder: Blind follow-up study at 8 years  

Microsoft Academic Search

The study objective was to examine the temporal stability of the antisocial personality disorder (ASPD) diagnosis based on whether specific antisocial symptoms were considered to be related to substance abuse. A total of 407 adults who were initially part of a family study of alcoholism and sociopathy were blindly reassessed an average of 8 years later, using the Home Environment

Stephen H Dinwiddie; E. Warwick Daw

1998-01-01

303

Follow-Up Study of Fiscal Year 2001 Occupational Program Graduates.  

ERIC Educational Resources Information Center

Results of a new statewide study on the benefits of the Illinois Community College System by economists document that community colleges have a strong positive impact on the state. The study found that investing in the completion of an associate degree translates into more than $345,000 in additional income over the remainder of a person's career,…

Illinois Community Coll. Board, Springfield.

304

Adjustment to University and Academic Performance: Brief Report of a Follow-Up Study  

ERIC Educational Resources Information Center

This study presents data that extend an earlier analysis of predictors of academic performance from one to three years. None of the adjustment and other psychosocial variables (help-seeking, academic motivation, self-esteem, perceived stress and perceived academic overload) could predict success at university at the end of three years of study.…

Petersen, Il-haam; Louw, Johann; Dumont, Kitty; Malope, Nomxolisi

2010-01-01

305

Ophthalmological follow up of preterm infants: a population based, prospective study of visual acuity and strabismus  

Microsoft Academic Search

BACKGROUND\\/AIMSPrematurely born infants are known to have an increased rate of ophthalmological morbidity. The aim of the present study was to investigate visual acuity and ocular alignment in a population of preterm infants in a geographical area, in infants with and without retinopathy of prematurity (ROP).METHODSA prospective population based study of ophthalmological status of preterm infants with a birth weight

G Holmström; M el Azazi; U Kugelberg

1999-01-01

306

On the course of low back pain in general practice: a one year follow up study  

Microsoft Academic Search

OBJECTIVESKnowledge on the clinical course of low back pain presented in general practice is poor. Preceding studies offer a fragmentary view only, whereas further knowledge is important to enable the assessment of the prognosis. The object of this study is to investigate the course of low back pain presented in general practice to enable the assessment of the prognosis.METHODSA one

Hans J M van den Hoogen; Bart W Koes; Jacques Th M van Eijk; Lex M Bouter; Walter Devillé

1998-01-01

307

The Bounce Back Retention Program: One-Year Follow-Up Study  

ERIC Educational Resources Information Center

This study provides results regarding the effectiveness of the Bounce Back Retention Program (BBRP), a semester-long voluntary course for students on academic probation (AP). This is the first phase of a longitudinal study of spring 2007 freshmen at San Diego State University (SDSU). Results were analyzed for three samples: 1) "AP BBRP-Credit"…

Hanger, Maria Andujo; Goldenson, Julie; Weinberg, Marsha; Schmitz-Sciborski, Amy; Monzon, Reynaldo

2012-01-01

308

MRI of hippocampus and entorhinal cortex in mild cognitive impairment: A follow-up study  

Microsoft Academic Search

The concept of mild cognitive impairment (MCI) has been proposed to represent a transitional stage between normal aging and dementia. We studied the predictive value of the MRI-derived volumes of medial temporal lobe (MTL) structures, white matter lesions (WML), neuropsychological tests, and Apolipoprotein E (APOE) genotype on conversion of MCI to dementia and AD. The study included 60 subjects with

Tero Tapiola; Corina Pennanen; Mia Tapiola; Susanna Tervo; Miia Kivipelto; Tuomo Hänninen; Maija Pihlajamäki; Mikko P. Laakso; Merja Hallikainen; Anne Hämäläinen; Matti Vanhanen; Eeva-Liisa Helkala; Ritva Vanninen; Aulikki Nissinen; Roberta Rossi; Giovanni B. Frisoni; Hilkka Soininen

2008-01-01

309

75 FR 77880 - Proposed Collection; Comment Request; GuLF Worker Study: Gulf Long-Term Follow-Up Study for Oil...  

Federal Register 2010, 2011, 2012, 2013, 2014

...Long-Term Follow-Up Study for Oil Spill Clean-Up Workers and Volunteers...Long-Term Follow-Up Study for Oil Spill Clean-Up Workers and Volunteers...long-term health effects associated with oil spill clean-up activities and...

2010-12-14

310

75 FR 62132 - Proposed Collection; Comment Request; GuLF Worker Study: Gulf Long-Term Follow-Up Study for Oil...  

Federal Register 2010, 2011, 2012, 2013, 2014

...Long-Term Follow-Up Study for Oil Spill Clean-Up Workers and Volunteers...Long-Term Follow-Up Study for Oil Spill Clean-Up Workers and Volunteers...long-term health effects associated with oil spill clean-up activities and...

2010-10-07

311

Study of enzyme replacement therapy for Gaucher Disease: comparative analysis of clinical and laboratory parameters at diagnosis and after two, five and ten years of treatment  

PubMed Central

Objective To evaluate the impact of enzyme replacement therapy for Gaucher Disease on clinical and laboratory parameters after two, five and ten years of treatment. Methods Data were collected from patient records and analyzed using BioEstat software (version 5.0). Student's t-test, Analysis of Variance (ANOVA), Wilcoxon test and Kruskal–Wallis test were used for statistical analysis. Hepatomegaly and splenomegaly were analyzed using the Kappa test. Results There was a significant increase in hemoglobin levels (p-value <0.01) and platelet counts (p-value = 0.01) within two years of therapy. At the same time, the frequencies of splenomegaly (p-value <0.01) and hepatomegaly (p-value <0.05) reduced. These results were similar at five and ten years of enzyme replacement therapy. Conclusions There are substantial and quick (within two years) laboratory and clinical responses to enzyme replacement therapy. These improvements continue as long as enzyme replacement therapy is administered every two weeks, as recommended by the literature. PMID:25305167

Souza, Ana Maria Almeida; Muniz, Thiago Pimentel; Brito, Rafael Maciel

2014-01-01

312

Treatment Compliance of Adolescents after Attempted Suicide: A 2-Year Follow-Up Study  

ERIC Educational Resources Information Center

The study investigates compliance with mental health treatments among suicidal adolescents. Results show that child psychopathology and parental attitudes toward treatment plays an important part in increasing compliance with mental health treatment for adolescent suicide attempters.

Burns, Craig D.; Cortell, Ranon; Wagner, Barry M.

2008-01-01

313

A follow-up study of Non-teacher certified Agricultural Education Department graduates  

E-print Network

The Agricultural Education field is expanding daily and Non-teaching Agricultural Education is highly regarded in this area of study. If the curriculum of Non-teaching Agricultural Education is to uphold its reputation and grow successfully...

Dailey, Amber Lynn

1999-01-01

314

Home versus hospital deliveries: follow up study of matched pairs for procedures and outcome. Zurich Study Team.  

PubMed Central

OBJECTIVE: To assess procedures and outcomes in deliveries planned at home versus those planned in hospital among women choosing the place of delivery. DESIGN: Follow up study of matched pairs. SETTING: Antenatal clinics and reference hospitals in Zurich between 1989 and 1992. SUBJECTS: 489 women opting for home delivery and 385 opting for hospital delivery; the women comprised all those attending members of the study team for antenatal care and those attending the reference hospital for antenatal care who could be matched with the women planning home confinement. MAIN OUTCOME MEASURES: Need for medication and incidence of interventions during delivery (caesarean section, forceps, vacuum extraction, episiotomy), duration of labour, occurrence of severe perineal lesions, maternal blood loss, and perinatal morbidity and death. RESULTS: All women were followed up from their first antenatal visit till three months after delivery. Referrals during pregnancy (n = 37) and labour (70), changes of mind (15 home to hospital, eight hospital to home), and 17 miscarriages resulted in 369 births occurring at home and 486 in hospital. During delivery the home birth group needed significantly less medication and fewer interventions whereas no differences were found in durations of labour, occurrence of severe perineal lesions, and maternal blood loss. Perinatal death was recorded in one planned hospital delivery and one planned home delivery (overall perinatal mortality 2.3/1000). There was no difference between home and hospital delivered babies in birth weight, gestational age, or clinical condition. Apgar scores were slightly higher and umbilical cord pH lower in home births, but these differences may have been due to differences in clamping and the time of transportation. CONCLUSION: Healthy low risk women who wish to deliver at home have no increased risk either to themselves or to their babies. PMID:8942694

Ackermann-Liebrich, U.; Voegeli, T.; Günter-Witt, K.; Kunz, I.; Züllig, M.; Schindler, C.; Maurer, M.

1996-01-01

315

Cognitive Functioning after Stroke: A One-Year Follow-Up Study  

Microsoft Academic Search

Cognitive disorders after stroke are one of the main causes of disability in daily activities. The main aim of this study was to investigate the frequency of post-stroke dementia, post-stroke mild cognitive impairment (MCI) and post-stroke amnestic MCI at different times after first-ever stroke; 196 patients were included in the study. In addition, cognitive disorders and their clinical course were

Sascha M. C. Rasquin; Jan Lodder; Rudolf W. H. M. Ponds; Ieke Winkens; Jelle Jolles; Frans R. J. Verhey

2004-01-01

316

Gender differences in outcomes of acute mania: a 12-month follow-up study  

Microsoft Academic Search

This study aimed to assess short-term (12 weeks) and long-term (12 months) gender differences in the outcomes of patients\\u000a experiencing an episode of mania in the course of bipolar disorder. European Mania in Bipolar Longitudinal Evaluation of Medication\\u000a was a 2-year, prospective, observational study of the outcomes of patients with a manic or mixed episode conducted in 14 European\\u000a countries. Data were

Laia Miquel; Judith Usall; Catherine Reed; Jordan Bertsch; Eduard Vieta; Ana González-Pinto; Jules Angst; Willem Nolen; Inge van Rossum; Josep Maria Haro

2011-01-01

317

Psychotropic drug use among people with dementia – a six-month follow-up study  

PubMed Central

Background Psychotropic drugs are widely used among old people with dementia but few studies have described long-term treatment in this group of patients. The purpose of this study was to explore the long-term use of psychotropic drugs in old people with dementia. Methods Data on psychotropic drug use, functioning in the activities of daily living (ADL), cognitive function and behavioral and psychological symptoms were collected at baseline and six months later, using the Multi-Dimensional Dementia Assessment Scale (MDDAS). The data were collected in 2005–2006. Detailed data about the prescribing of psychotropic drugs were collected from prescription records. This study was conducted in 40 specialized care units in northern Sweden, with a study population of 278 people with dementia. Results At the start of the study, 229 of the participants (82%) were prescribed at least one psychotropic drug; 150 (54%) used antidepressants, 43 (16%) used anxiolytics, 107 (38%) used hypnotics and sedatives, and 111 (40%) used antipsychotics. Among the baseline users of antidepressants, anxiolytics, hypnotics and sedatives and antipsychotics, 67%, 44%, 57% and 57% respectively, still used the same dose of the same psychotropic drug after six months. Associations were found between behavioral and psychological symptoms and different psychotropic drugs. Conclusion Psychotropic drug use was high among people with dementia living in specialized care units and in many cases the drugs were used for extended periods. It is very important to monitor the effects and adverse effects of the prescribed drug in this frail group of people. PMID:24196341

2013-01-01

318

Genome-wide linkage and follow-up association study of postpartum mood symptoms  

PubMed Central

Objective Family studies have suggested that postpartum mood symptoms might have a partly genetic etiology. The authors used a genome-wide linkage analysis to search for chromosomal regions that harbor genetic variants conferring susceptibility for such symptoms. The authors then fine-mapped their best linkage regions, assessing single nucleotide polymorphisms (SNPs) for genetic association with postpartum symptoms. Method Subjects were ascertained from two studies: the NIMH Genetics Initiative Bipolar Disorder project and the Genetics of Recurrent Early-Onset Depression. Subjects included women with a history of pregnancy, any mood disorder, and information about postpartum symptoms. In the linkage study, 1,210 women met criteria (23% with postpartum symptoms), and 417 microsatellite markers were analyzed in multipoint allele sharing analyses. For the association study, 759 women met criteria (25% with postpartum symptoms), and 16,916 SNPs in the regions of the best linkage peaks were assessed for association with postpartum symptoms. Results The maximum linkage peak for postpartum symptoms occurred on chromosome 1q21.3-q32.1, with a chromosome-wide significant likelihood ratio Z score (ZLR) of 2.93 (permutation p=0.02). This was a significant increase over the baseline ZLR of 0.32 observed at this locus among all women with a mood disorder (permutation p=0.004). Suggestive linkage was also found on 9p24.3-p22.3 (ZLR=2.91). In the fine-mapping study, the strongest implicated gene was HMCN1 (nominal p=0.00017), containing four estrogen receptor binding sites, although this was not region-wide significant. Conclusions This is the first study to examine the genetic etiology of postpartum mood symptoms using genome-wide data. The results suggest that genetic variations on chromosomes 1q21.3-q32.1 and 9p24.3-p22.3 may increase susceptibility to postpartum mood symptoms. PMID:19755578

Mahon, PB; Payne, JL; MacKinnon, DF; Mondimore, FM; Goes, FS; Schweizer, B; Jancic, D; Coryell, WH; Holmans, PA; Shi, J; Knowles, JA; Scheftner, WA; Weissman, MM; Levinson, DF; DePaulo, JR; Zandi, PP; Potash, JB

2013-01-01

319

STAR Follow-Up Studies, 1996-1997: The Student/Teacher Achievement Ratio (STAR) Project.  

ERIC Educational Resources Information Center

The Student/Teacher Achievement Ratio (STAR) Project first investigated the effect of small class size on student achievement with over 6,000 Tennessee primary students in 1985 through 1989. The study found a consistent and significant benefit of small classes for all students, with the greatest advantages for minority, inner-city students from…

Pate-Bain, Helen; Boyd-Zaharias, Jayne; Cain, Van A.; Word, Elizabeth; Binkley, M. Edward

320

Adolescent and adult leisure patterns: A 37?year follow?up study  

Microsoft Academic Search

The relationship between adolescent and adult leisure activities was assessed by utilizing longitudinal data from 1298 subjects studied during their high school years and again when they were in their early fifties. For the sample members, the greater the involvement in a specific type of activity during adolescence, the more frequent the participation in the same type of activity at

David Scott; Fern K. Willits

1989-01-01

321

Coping with Serious Accidental Injury: A One-Year Follow-Up Study  

Microsoft Academic Search

Background: The aim of this study was to analyze changes of coping strategies in severely injured accident victims over time and to compare patients with high and low posttraumatic stress disorder (PTSD) symptom levels with regard to their coping patterns and accident-related cognitions. Methods: 106 consecutive patients with severe accidental injuries admitted to a trauma surgery intensive care unit (ICU)

Urs Hepp; Hanspeter Moergeli; Stefan Büchi; Lutz Wittmann; Ulrich Schnyder

2005-01-01

322

A Follow-Up Study of Junior College Hotel and Restaurant Education in Florida.  

ERIC Educational Resources Information Center

This study examines hospitality programs from the enabling legislation in 1961, which provided for an advisory committee to the Hotel and Restaurant Commission on education. Its purpose was to employ a director of the programs and two field representatives or consultants to offer on-the-job assistance to managers and employees in the state's…

Almarode, Richard L.

323

Follow-up Study of Rehabilitation Clients: A Step-By-Step Guide.  

ERIC Educational Resources Information Center

This manual is designed to aid the user in measuring consumer satisfaction with vocational rehabilitation services. The manual contains materials which were used by the West Virginia Research and Training Center in a followup study. Step-by-step guidelines are provided for assessing the effectiveness of vocational rehabilitation services by…

Greever, Kathryn B.; And Others

324

Relationships in couples after failed IVF treatment: a prospective follow-up study  

Microsoft Academic Search

BACKGROUND: There are few studies of couples that analyse satisfaction with treatment, adoption plans and relationships in couples after unsuccessful IVF. METHODS: ENRICH marital inventory was used to describe marital dynamics and to gain information about treatment and adoption plans. A specially designed questionnaire was used. Of the 51 couples without previous children who were asked to participate after their

Gunilla Sydsjo; Katarina Ekholm; Marie Wadsby; Svante Kjellberg; Adam Sydsjo

325

Adolescent Personality and School and College Performance: A Follow-Up Study.  

ERIC Educational Resources Information Center

Reports correlations between the High School Personality Questionnaire and various indices of school achievement and compares the validities with prior studies. Uses three achievement scores: self-reported high-school grades, parent-reported high-school grades several years after the testing, and college grades several years after the testing. The…

Schuerger, J. M.; Kuna, D. L.

1987-01-01

326

Cognitive Deficits Associated with Acquired Amusia after Stroke: A Neuropsychological Follow-Up Study  

ERIC Educational Resources Information Center

Recent evidence on amusia suggests that our ability to perceive music might be based on the same neural resources that underlie other higher cognitive functions, such as speech perception and spatial processing. We studied the neural correlates of acquired amusia by performing extensive neuropsychological assessments on 53 stroke patients with a…

Sarkamo, Teppo; Tervaniemi, Mari; Soinila, Seppo; Autti, Taina; Silvennoinen, Heli M.; Laine, Matti; Hietanen, Marja

2009-01-01

327

Executive Inhibitory Control and Cooperative Behavior during Early School Years: A Follow-Up Study  

ERIC Educational Resources Information Center

Several links between aspects of executive functioning and the development of social competence have been established. The present study investigates the relation between executive inhibitory control and cooperative/non-cooperative behavior, in an ecological setting, and from a longitudinal perspective. Elementary school children (n = 195) of…

Ciairano, Silvia; Visu-Petra, Laura; Settanni, Michele

2007-01-01

328

Measuring Phonological Development: A Follow-Up Study of Five Children Acquiring Finnish  

ERIC Educational Resources Information Center

This study applies the Phonological Mean Length of Utterance measurement (PMLU; Ingram & Ingram, 2001; Ingram, 2002) to the data of five children acquiring Finnish and evaluates their phonological development longitudinally at four different age points: 2;0, 2;6, 3;0, and 3;6. The children's results on PMLU and related measures are discussed…

Saaristo-Helin, Katri

2009-01-01

329

Natural History of Thyroid Function in Adults with Down Syndrome--10-Year Follow-Up Study  

ERIC Educational Resources Information Center

Background: The natural history of thyroid function in adults with Down syndrome (DS) is unknown. Method: This study investigated annual thyroid function tests in 200 adults with DS over a 10-year period. Results: Transient and persistent thyroid dysfunction was common. The 5- and 10-year incidence of definite hypothyroidism was 0.9%-1.64% and…

Prasher, V.; Gomez, G.

2007-01-01

330

A Follow-Up Study of Eco Education's Environmental Service-Learning Program  

ERIC Educational Resources Information Center

The purpose of the study is to determine student views of the influence of the Eco Education Urban Stewards program's impact on their involvement in community environmental initiatives. Eco Education is a non-profit organization in St. Paul that facilitates an urban, environmental, year-long science curriculum delivered in middle schools in…

Hobert, Thomas Milton

2010-01-01

331

Persistence of bullying from childhood to adolescence—a longitudinal 8-year follow-up study  

Microsoft Academic Search

Objective: To examine factors associated with bullying and victimization from age 8 to 16.Method: An 8-year longitudinal study included questions about bullying and victimization at age 8 and 16. Children were evaluated with Rutter scales by parents and teachers and with the Child Depression Inventory filled in by the children at age 8. When the children were at the age

Andre Sourander; Leila Helstelä; Hans Helenius; Jorma Piha

2000-01-01

332

Emotional Psychopathology and Increased Adiposity: Follow-Up Study in Adolescents  

ERIC Educational Resources Information Center

Based on data from a three-year longitudinal study, we assess the effect, according to gender, of emotional psychopathology in preadolescence on anthropometric and body composition parameters in adolescence (N = 229). Psychopathology was assessed using the "Screen for Childhood Anxiety and Related Emotional Disorders, the Children's Depression…

Aparicio, Estefania; Canals, Josefa; Voltas, Nuria; Hernandez-Martinez, Carmen; Arija, Victoria

2013-01-01

333

Empowering Visuo-Spatial Ability in Primary School: Results from a Follow-Up Study  

ERIC Educational Resources Information Center

The current study was primarily aimed at verifying the effect of a combined computer-assisted and pencil-and-paper training that was developed to empower visuo-spatial abilities in primary school pupils. One hundred and twenty third grade (mean average: eight years old) and fourth grade (mean age: nine years old) students attending several Italian…

Fastame, Maria Chiara; Callai, Daniela

2015-01-01

334

A 1 and 2 Year Follow-up Study of Adoptive Families and Special Needs Children.  

ERIC Educational Resources Information Center

Provides an overview of issues that families encounter over time in the adoption of children with special needs. Reports on a two-year survey of special needs adoption, which supported much of the conclusions provided by cross-sectional studies. Implications of the findings for the service system are discussed. (TJQ)

Groze, Victor

1996-01-01

335

A clinical and statistical follow-up study of atrophic gastritis  

Microsoft Academic Search

A study was made of 363 patients 11 to 18 years after initial biopsies and gastric secretory findings. Investigation of the cause of death revealed the development of gastric carcinoma in 13% of the cases which had prior findings of atrophic gastritis. Statistical analysis of the cases led to additional evidence that atrophic gastritis may constitute a predisposition for the

R. Cheli; G. Ciancamerla

1973-01-01

336

Follow-Up Study of Fiscal Year 1997 Occupational Program Graduates, 1998.  

ERIC Educational Resources Information Center

This report provides information from graduates of selected occupational programs regarding the effectiveness of their Illinois community college experience. The study surveyed a pool of 2,190 occupational program graduates, which yielded a usable response rate of 58.6%. The majority of graduate respondents (64.5%) came from programs in four…

Illinois Community Coll. Board, Springfield.

337

Early predictors of career development: A 10-year follow-up study  

Microsoft Academic Search

This paper presents empirical findings from a 10-year longitudinal study of the educational and occupational socialization of 445 participants who were about 7 years old when first tested, and about 17 years old at the fourth time of measurement. In addition to collecting psychological measurements from the participants, behavioral reports were collected from significant others, specifically parents and teachers. Findings

Joaquim Armando Ferreira; Eduardo J. R. Santos; António C. Fonseca; Richard F. Haase

2007-01-01

338

A Follow-Up Study to Compare Success Rates of Developmental Math Students  

ERIC Educational Resources Information Center

This article presents a study that compared the success rates of students in Arithmetic (MTH 02), Algebra I (MTH 03), and Algebra II (MTH 03) when they were offered at Southwest Virginia Community College (SWCC) for three credits versus five credits. The authors' findings showed no significant differences in the success rates of students who were…

Woodard, Teresa; Burkett, Sexton

2010-01-01

339

Evaluation Services from Needs Assessment to Follow-up: A Case Study.  

ERIC Educational Resources Information Center

This paper describes the nature and scope of evaluation services provided within the training division of Arthur Andersen & Company, and highlights some of the evaluation results. The cycle of assessment began with a needs assessment study at the curriculum level. Curriculum planning was undertaken for first-year trainees in the Tax Division. A…

Broadbooks, Wendy J.

340

The Impact of Arbitration Intervention Services on Psychosocial Functioning: A Follow-Up Study  

ERIC Educational Resources Information Center

We report the impact of case management services on drug use and self-reported delinquency for youths involved in a clinical trial of the Juvenile Arbitration program. The project evaluated an innovative intervention service providing 16 weeks of intensive case management services to youths and their families. The present study examines interview…

Dembo, Richard; Wareham, Jennifer; Poythress, Norman G.; Cook, Brittany; Schmeidler, James

2006-01-01

341

Follow-up Study of Doctoral Program Graduates and Their Employers.  

ERIC Educational Resources Information Center

In accordance with Standard II.B of the National Council for the Accreditation of Teacher Education concerning the maintenance of relationships with graduates of professional education programs, this study surveyed all graduates (N=86) of doctoral-level programs in the College of Education at Mississippi State University from 1986 through 1989.…

Ruthven, A. Jan

342

National Transition Follow-Up Study of Youth Identified as Deafblind: Parent Perspectives. NTAC Briefing Paper.  

ERIC Educational Resources Information Center

This study surveyed the parents/guardians of 97 youth (ages 18-24) throughout the United States who are deaf-blind and who left school in June 1996. The survey was conducted 18 months after these youth had left school. Following an introduction, this report first presents findings related to characteristics of the youth in the areas of…

Petroff, Jerry G.

343

Freshman withdrawal from college: A positive step toward identity formation? A follow-up study  

Microsoft Academic Search

Withdrawal from college can be a positive step toward separation from parents and identity formation. Subjects for the present study were all persons who withdrew from a random sample of 432 members of a large freshman class (154 males and 278 females). Subjects were divided into withdrawers versus continuers, with the former group being subdivided into transfers versus nontransfers and

Frank R. Timmons

1978-01-01

344

Early Predictors of Career Development: A 10-Year Follow-up Study  

ERIC Educational Resources Information Center

This paper presents empirical findings from a 10-year longitudinal study of the educational and occupational socialization of 445 participants who were about 7 years old when first tested, and about 17 years old at the fourth time of measurement. In addition to collecting psychological measurements from the participants, behavioral reports were…

Ferreira, Joaquim Armando; Santos, Eduardo J. R.; Fonseca, Antonio C.; Haase, Richard F.

2007-01-01

345

Follow-up Prostate Cancer Treatments After Radical Prostatectomy: a Population-Based Study  

Microsoft Academic Search

Background: Radical prostatectomy is one of the most com- monly used curative procedures for the treatment of local- ized prostate cancer. The probability that a patient will undergo additional cancer therapy after this procedure is largely unknown. Purpose: The objective was to determine the likelihood of additional cancer therapy after radical prostatectomy. Methods: Data for this study were derived from

Grace L. Lu-Yao; Arnold L. Potosky; Peter C. Albertsen; John H. Wasson; Michael J. Barry; John E. Wennberg

346

10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study  

PubMed Central

Summary Background In the 2·8 years of the Diabetes Prevention Program (DPP) randomised clinical trial, diabetes incidence in high-risk adults was reduced by 58% with intensive lifestyle intervention and by 31% with metformin, compared with placebo. We investigated the persistence of these effects in the long term. Methods All active DPP participants were eligible for continued follow-up. 2766 of 3150 (88%) enrolled for a median additional follow-up of 5·7 years (IQR 5·5–5·8). 910 participants were from the lifestyle, 924 from the metformin, and 932 were from the original placebo groups. On the basis of the benefits from the intensive lifestyle intervention in the DPP, all three groups were offered group-implemented lifestyle intervention. Metformin treatment was continued in the original metformin group (850 mg twice daily as tolerated), with participants unmasked to assignment, and the original lifestyle intervention group was offered additional lifestyle support. The primary outcome was development of diabetes according to American Diabetes Association criteria. Analysis was by intention-to-treat. This study is registered with ClinicalTrials.gov, number NCT00038727. Findings During the 10·0-year (IQR 9·0–10·5) follow-up since randomisation to DPP, the original lifestyle group lost, then partly regained weight. The modest weight loss with metformin was maintained. Diabetes incidence rates during the DPP were 4·8 cases per 100 person-years (95% CI 4·1–5·7) in the intensive lifestyle intervention group, 7·8 (6·8–8·8) in the metformin group, and 11·0 (9·8–12·3) in the placebo group. Diabetes incidence rates in this follow-up study were similar between treatment groups: 5·9 per 100 person-years (5·1–6·8) for lifestyle, 4·9 (4·2–5·7) for metformin, and 5·6 (4·8–6·5) for placebo. Diabetes incidence in the 10 years since DPP randomisation was reduced by 34% (24–42) in the lifestyle group and 18% (7–28) in the metformin group compared with placebo. Interpretation During follow-up after DPP, incidences in the former placebo and metformin groups fell to equal those in the former lifestyle group, but the cumulative incidence of diabetes remained lowest in the lifestyle group. Prevention or delay of diabetes with lifestyle intervention or metformin can persist for at least 10 years. Funding National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). PMID:19878986

2011-01-01

347

Follow up study of near infrared (1100 to 1319 nm) retinal damage thresholds and trends  

NASA Astrophysics Data System (ADS)

A study of retinal damage thresholds in non-human primates (NHP) in the near-infrared (NIR) wavelengths of 1110, 1130, 1150, and 1319 nm has recently been reported. The progression of damage in retinal areas that received exposures below, greater than, and at threshold values for each respective wavelength are compared. Subjects were imaged using an Adaptive Optics (AO) enhanced Spectral Domain Optical Coherence Tomographer (SD-OCT) a year post laser exposure to examine damage characteristics and localization. The subject's retinas within the study exhibited a delayed response to NIR exposures in that many of the lesions that were not visible at the 1-hour observation period continued to grow in size over the 24-hour period and or became visible. Thermal lensing is believed to play a significant role in the formation or retinal lesions in the NIR and may explain the delayed response.

Pocock, Ginger M.; Oliver, Jeff W.; Noojin, Gary D.; Schuster, Kurt J.; Stolarski, David; Shingledecker, Aurora; Rockwell, Benjamin A.

2010-02-01

348

Radial fracture as an indicator of osteoporosis: a 10-year follow-up study  

PubMed Central

Of 136 patients studied at an average of 10.6 years after a distal radial fracture, 37.6% of the 109 women and 7.4% of the 27 men suffered a subsequent fracture. “Osteoporosis-related” fractures accounted for the majority of subsequent fractures sustained by the women. The prognostic significance of distal radial fracture in the adult female is discussed. PMID:4842567

Gay, J. D. L.

1974-01-01

349

Prognostic significance of transient myocardial ischaemia after first acute myocardial infarction: five year follow up study  

Microsoft Academic Search

OBJECTIVE--To assess the five year prognostic significance of transient myocardial ischaemia on ambulatory monitoring after a first acute myocardial infarction, and to compare the diagnostic and long term prognostic value of ambulatory ST segment monitoring, maximal exercise testing, and echocardiography in patients with documented ischaemic heart disease. DESIGN--Prospective study. SETTING--Cardiology department of a teaching hospital. PATIENTS--123 consecutive men aged under

H. Mickley; J. R. Nielsen; J. Berning; A. Junker; M. Møller

1995-01-01

350

Relations Between Achievement Goal Orientations and Math Achievement in Primary Grades: A Follow?Up Study  

Microsoft Academic Search

The aim of the present study was to investigate children’s achievement goal orientations and their relations to math achievement in the primary grades. The sample consisted of 179 children who were in the 2nd and 3rd grades during the first measurement and in the 3rd and 4th grades during the second measurement. Children’s self?ratings were obtained on their goal orientations,

Katrin Mägi; Eve Kikas

2010-01-01

351

Immediate resin-bonded bridgework: results of a medium-term clinical follow-up study.  

PubMed

A total of 21 immediate resin-bonded bridges were inserted under controlled and standardized clinical conditions and evaluated over a period of 35 months. During the evaluation period, two bridges debonded (9.5%). The debonded bridges were re-cemented successfully. This low incidence of debonding indicates that this simple alternative procedure for the immediate replacement of a single unsaveable tooth was satisfactory. The subjects included in this study expressed their satisfaction with this form of treatment. PMID:15125604

Al-Wahadni, A M; Al-Omari, W M

2004-01-01

352

5-year follow-up of a prospective clinical study on various types of core restorations  

Microsoft Academic Search

PURPOSE: This study tested whether: (1) the survival rate of cast post-and-core restorations is better than the survival of direct post-and-core restorations and post-free all-composite cores; and (2)the survival of these buildup restorations is influenced by the remaining dentin height after preparation. MATERIALS AND METHODS: In a clinical trial, 18 operators made 319 core restorations in 249 patients. The restorations

N. H. J. Creugers; A. G. B. Mentink; W. A. Fokkinga; C. M. Kreulen

2005-01-01

353

Post-stroke pain on long-term follow-up: the Bergen stroke study  

Microsoft Academic Search

The objective of this study is to evaluate characteristics and mortality related to long-term post-stroke pain (PSP). All\\u000a surviving stroke patients admitted to the Stroke Unit, Haukeland University Hospital, between February 2006 and July 2009\\u000a received a postal questionnaire including the fatigue severity scale (FSS), the hospital anxiety and depression scale (HADSD),\\u000a the Barthel index (BI), and questions regarding location

Halvor Naess; Lene Lunde; Jan Brogger; Ulrike Waje-Andreassen

2010-01-01

354

Primary sclerosing cholangitis in children: A long-term follow-up study  

Microsoft Academic Search

Primary sclerosing cholangitis (PSC) is increasingly diagnosed in children and adolescents, but its long-term prognosis remains uncertain. The aim of this longitudinal, cohort study was to determine the long-term outcome of children with PSC. Fifty-two children with cholangiography-proven PSC (34 boys and 18 girls; mean age 13.8 ± 4.2 years; range, 1.5-19.6 years) who were seen at our institution over

Ariel E. Feldstein; Jean Perrault; Mounif El-Youssif; Keith D. Lindor; Deborah K. Freese; Paul Angulo

2003-01-01

355

A follow-up study of Eco Education's environmental service-learning program  

Microsoft Academic Search

The purpose of the study is to determine student views of the influence of the Eco Education Urban Stewards program's impact on their involvement in community environmental initiatives. Eco Education is a non-profit organization in St. Paul that facilitates an urban, environmental, year-long science curriculum delivered in middle schools in Minnesota. The year-long program ends with an urban, environmental service-learning

Thomas Milton Hobert

2010-01-01

356

Review of 1953-2003 ORAU Follow-Up Studies on Science Education Programs: Impacts on Participants' Education and Careers  

SciTech Connect

Through sponsorship of science education programs for undergraduates and graduates, such as research participation programs and fellowships, the Department of Energy (DOE) encouraged the development of adequate numbers of qualified science and engineering (S&E) personnel to meet its current and future research and development (R&D) needs. This retrospective study summarizes impacts of selected programs on these participants. The summary data are from follow-up studies conducted from 1953 through 2003 by Oak Ridge Associated Universities and its predecessor, the Oak Ridge Institute for Nuclear Studies (ORINS).

Oak Ridge Associated Universities

2006-06-01

357

Menstrual function among women exposed to polybrominated biphenyls: A follow-up prevalence study  

PubMed Central

Background Alteration in menstrual cycle function is suggested among rhesus monkeys and humans exposed to polybrominated biphenyls (PBBs) and structurally similar polychlorinated biphenyls (PCBs). The feedback system for menstrual cycle function potentially allows multiple pathways for disruption directly through the hypothalamic-pituitary-ovarian axis and indirectly through alternative neuroendocrine axes. Methods The Michigan Female Health Study was conducted during 1997–1998 among women in a cohort exposed to PBBs in 1973. This study included 337 women with self-reported menstrual cycles of 20–35 days (age range: 24–56 years). Current PBB levels were estimated by exponential decay modeling of serum PBB levels collected from 1976–1987 during enrollment in the Michigan PBB cohort. Linear regression models for menstrual cycle length and the logarithm of bleed length used estimated current PBB exposure or enrollment PBB exposure categorized in tertiles, and for the upper decile. All models were adjusted for serum PCB levels, age, body mass index, history of at least 10% weight loss in the past year, physical activity, smoking, education, and household income. Results Higher levels of physical activity were associated with shorter bleed length, and increasing age was associated with shorter cycle length. Although no overall association was found between PBB exposure and menstrual cycle characteristics, a significant interaction between PBB exposures with past year weight loss was found. Longer bleed length and shorter cycle length were associated with higher PBB exposure among women with past year weight loss. Conclusion This study suggests that PBB exposure may impact ovarian function as indicated by menstrual cycle length and bleed length. However, these associations were found among the small number of women with recent weight loss suggesting either a chance finding or that mobilization of PBBs from lipid stores may be important. These results should be replicated with larger numbers of women exposed to similar lipophilic compounds. PMID:16091135

Davis, Stephanie I; Blanck, Heidi Michels; Hertzberg, Vicki S; Tolbert, Paige E; Rubin, Carol; Cameron, Lorraine L; Henderson, Alden K; Marcus, Michele

2005-01-01

358

Is prenatal tobacco exposure a risk factor for early adolescent smoking? A follow-up study.  

PubMed

Recent reports indicate a relation between prenatal tobacco exposure (PTE) and offspring smoking. Many of these reports have been retrospective or have not included important variables such as other prenatal substance exposures, maternal and child psycho-social characteristics, mother's current smoking, and friends' smoking. No prior study has examined the timing of PTE. In this prospective study of a birth cohort of 567 14-year-olds, we examined the relation between trimester-specific PTE, offspring smoking, and other correlates of adolescent smoking. Average age of the adolescents was 14.8 years (range: 13.9-16.6 years), 51% were female, 54% were African-American. Data on maternal tobacco and other substance use were collected both prenatally and postnatally, 51% of the mothers were prenatal smokers and 53% smoked when their children were 14 years. PTE in the third trimester significantly predicted offspring smoking (ever/never, smoking level, age of onset) when demographic and other prenatal substances were included in the analyses. PTE remained a significant predictor of the level of adolescent smoking when maternal and child psychological characteristics were added to the model. When more proximal measures of the child's smoking were included in the model, including mother's current smoking and friends' smoking, PTE was no longer significant. Significant predictors of adolescent smoking at age 14 were female gender, Caucasian race, child externalizing behavior, maternal anxiety, and child depressive symptoms. Although direct effects of PTE on offspring smoking behavior have previously been reported from this study and by others, by early-adolescence, this association is not significant after controlling for the more proximal covariates of adolescent smoking such as mother's current smoking and peer smoking. PMID:16014324

Cornelius, Marie D; Leech, Sharon L; Goldschmidt, Lidush; Day, Nancy L

2005-01-01

359

A one-year follow-up study into the course of depression after stroke  

Microsoft Academic Search

Background  Stroke patients commonly suffer from neuropsychiatric disorders, such as depression, that negatively influence stroke outcome.\\u000a Diagnosis, treatment and prevention of post-stroke psychiatric disorders including depression are under debate.\\u000a \\u000a \\u000a \\u000a \\u000a Objective  To study the course of depression after stroke.\\u000a \\u000a \\u000a \\u000a Methods  One hundred and ninety first-ever stroke patients were screened for depressive symptoms at 1, 3, 6, 9, and 12 months after\\u000a stroke. Diagnosis of

A. Bour; S. Rasquin; I. Aben; A. Boreas; M. Limburg; F. Verhey

2010-01-01

360

Why are antiretroviral treatment patients lost to follow-up? A qualitative study from South Africa  

PubMed Central

Objectives To better understand the reasons why patients default from antiretroviral treatment (ART) programmes to help design interventions that improve treatment retention and ultimately, patient outcomes. Methods Prospective cohort study at two treatment sites in South Africa followed by qualitative interviews with patients that had defaulted. Results Respondents overwhelmingly reported that ART improved their health status and quality of life. Nevertheless, despite improved health from taking ART and worse health when treatment is stopped, serious barriers to treatment remained: transport costs, time needed for treatment, and logistical challenges were barriers to treatment, whereas stigma around HIV/AIDS, and side effects associated with ART were less influential. Conclusion With a better understanding of the reasons for defaulting, interventions can be designed that improve treatment retention and ultimately, patient outcomes. This study argues for realistic interventions and policy changes designed to reduce the financial and time burden of ART and to reduce logistical barriers, such as simplifying the referral and transfer process, employing patient advocates, and adopting extended and weekend clinic hours. PMID:20586960

Miller, Candace M; Ketlhapile, Mpefe; Rybasack-Smith, Heather; Rosen, Sydney

2010-01-01

361

Patients' experiences after bariatric surgery: a qualitative study at 12-month follow-up.  

PubMed

This study used a qualitative approach to understand patients' experiences in post-surgery adaptation related to bariatric surgery, 12 months after this procedure. The study population included 30 obese adults, with a mean age of 40.17 years, who were interviewed 12 months after bariatric surgery. Individual interviews, using open-ended questions, were audiotaped, transcribed and coded according to the grounded theory methodology. The data showed that the subjects described themselves as belonging to one of two opposite and separate groups: success or failure. In both groups, two core categories emerged from the data: outcomes and treatment. Previous expectations were reached by the patients who described themselves as successful, with some remaining concerns related to future weight maintenance and aesthetics issues. The failure group emphasized their unmet expectations and the expectancy that surgery would change their lives remained. Treatment in the successful cases integrated lifestyle changes and bariatric surgery, highlighting the personal commitment required to achieve the objectives. The failure group emphasized bariatric surgery without personal commitment, and healthy eating behaviour was understood as a sacrifice. The post-surgical adaptation experiences were diverse: the cases that were described as a success highlighted lifestyle changes, personal efforts and commitment with the global treatment process. External understanding and the desire for a miracle surgery characterized the cases described as a failure. According to these results, it is necessary to promote adequate information about the whole process and skills required to ensure commitment in all treatment dimensions. PMID:25586735

da Silva, Susana Sofia Pereira; Maia, Ângela da Costa

2013-12-01

362

Prospective study of treatment outcome of implant retained mandibular overdenture: Two years follow-up  

PubMed Central

Aims: The aim of this study is to evaluate the treatment outcome of immediately loaded Implants in the interforaminal region of anterior mandible. Materials and Methods: A total of 15 completely edentulous patients aged between 50 and 70 years were selected satisfying certain inclusion and exclusion criteria. Two implants were placed in 33 and 43 region (B and D location) and the implants were loaded immediately by mandibular overdenture retained with O-ring attachments. The implants were evaluated for various clinical parameters at 6 months, 1 year, 1.5 years, and 2 years intervals after initial placement. Results: There was increased marginal bone loss around implants during the 1st year after that the bone loss was insignificant. Clinical stability of immediately loaded implants was lower initially for 6 months, but improved by the end of 1st year. Survival rate for immediately loaded implants was 96.6% at the end of the period of study. Conclusion: Immediate loading of interforaminal mandibular implants demonstrated a highly acceptable clinical success at the end of 2 years. However, initially the marginal bone level and clinical stability were significantly lower which showed improvement with time. PMID:24963237

Arora, Vimal; Kumar, Dinesh; Legha, V. S.; Arun Kumar, K. V.

2014-01-01

363

Sutureless femtosecond anterior lamellar keratoplasty: A 1-year follow-up study  

PubMed Central

Aim: To study the safety and efficacy of sutureless femtosecond anterior lamellar keratoplasty (FALK) in patients with corneal stromal opacities. Materials and Methods: Eleven eyes of 11 consecutive patients with corneal stromal opacities involving < 250 ? due to various pathologies were included in the study. Preoperatively, all underwent anterior segment imaging with spectral domain optical coherence tomography (SD-OCT) (Bioptigen Inc., Durham, North Carolina, USA) to measure the depth of the stromal opacity. All patients underwent FALK, and bandage contact lens was placed for a period of 2 weeks. Postoperatively, uncorrected visual acuity, best corrected visual acuity (BCVA), and SD-OCT evaluation were performed. Results: All patients showed significant improvement in BCVA. The mean postoperative BCVA (in decimals) improved from 0.11 ± 0.06 preoperatively to 0.59 ± 0.08. There were no intraoperative or significant postoperative complications that were noticed. Conclusion: FALK is a safe and effective alternative to deep anterior lamellar keratoplasty or penetrating keratoplasty in the treatment of anterior stromal opacities. PMID:25370393

Shetty, Rohit; Nagaraja, Harsha; Veluri, Himabindu; Shivanna, Yathish; Kugar, Thungappa; Nujits, Rudy; Shetty, Bhujang

2014-01-01

364

Childhood friendships and psychological difficulties in young adulthood: an 18-year follow-up study.  

PubMed

Childhood friendships have been shown to impact mental health over the short term; however, it is unclear whether these effects are sustained into young adulthood. We studied the prospective association between childhood friendships and psychological difficulties in young adulthood. Data come from 1,103 French 22-35 year olds participating in the TEMPO study. Childhood friendships were ascertained in 1991 when participants were 4-16 years old. Psychological difficulties were measured in 2009 using the Adult Self-Report. Logistic regression models controlled for participants' age, sex, childhood psychological difficulties and parental characteristics. Young adults who had no childhood friends had higher odds of psychological difficulties than those with at least one friend: (adjusted ORs 2.45; 95 % CI 1.32-4.66, p = 0.01 for high internalizing symptoms; 1.81; 95 % CI 0.94-3.54, p = 0.08 for high externalizing symptoms). Social relations early in life may have consequences for adult psychological well-being. PMID:25316094

Sakyi, Kwame S; Surkan, Pamela J; Fombonne, Eric; Chollet, Aude; Melchior, Maria

2014-10-15

365

Homocysteine as a Risk Factor for Hypertension: A 2-Year Follow-Up Study  

PubMed Central

Homocysteine (Hcy) is regarded as a risk factor for hypertension, but research on the causal relationship between Hcy and hypertension is limited. In the present study, we prospectively tracked the blood pressure progression of a normotensive population with different Hcy levels over a 2-year period. The incidence of hypertension with increasing Hcy quartiles produced an approximately U-shaped curve, with significance in males. Compared with the third quartile, the risk of hypertension in the first and second quartiles was increased by 1.55 (95% confidence interval [CI] 1.154–2.081) fold and 1.501 (95% CI 1.119–2.013) fold, respectively, with the increase being more significant in males. In conclusion, Hcy is related to hypertension incidence with the results approximating an U-shaped curve. Low Hcy levels might also increase the risk of hypertension. PMID:25310282

Yao, Tao; Li, DongQing; Wang, YanXiu; Li, YuQing; Wu, ShouLing; Cai, Jun

2014-01-01

366

Mood and cognition after electrical injury: a follow-up study.  

PubMed

Individuals who have experienced an electrical injury have been reported to demonstrate both acute and delayed cognitive and psychiatric symptoms. The present study assessed 20 electrically injured patients who underwent neuropsychological evaluations twice following their injury. Time since injury, time between assessments, and longitudinal mood changes were evaluated for their potential impact on simple and complex attention outcomes. As an overall group, there was little change over time from low average to average baseline attention/concentration performance. However, results indicated that longitudinal increases in depressive symptoms were consistently associated with poorer performance on a measure of simple and complex attention. Loss of consciousness, litigation status, baseline injury status (acute vs. post-acute), and time between evaluations were not significant predictors of changes in cognitive performance. Implications for the treatment of comorbid psychiatric issues and for future research on victims of electrical trauma are discussed. PMID:24395352

Aase, Darrin M; Fink, Joseph W; Lee, Raphael C; Kelley, Kathleen M; Pliskin, Neil H

2014-03-01

367

Comparative clinical study of the effectiveness of different dental bleaching methods - two year follow-up  

PubMed Central

This study evaluated color change, stability, and tooth sensitivity in patients submitted to different bleaching techniques. Material and methods In this study, 48 patients were divided into five groups. A half-mouth design was conducted to compare two in-office bleaching techniques (with and without light activation): G1: 35% hydrogen peroxide (HP) (Lase Peroxide - DMC Equipments, São Carlos, SP, Brazil) + hybrid light (HL) (LED/Diode Laser, Whitening Lase II DMC Equipments, São Carlos, SP, Brazil); G2: 35% HP; G3: 38% HP (X-traBoost - Ultradent, South Jordan UT, USA) + HL; G4: 38% HP; and G5: 15% carbamide peroxide (CP) (Opalescence PF - Ultradent, South Jordan UT, USA). For G1 and G3, HP was applied on the enamel surface for 3 consecutive applications activated by HL. Each application included 3x3' HL activations with 1' between each interval; for G2 and G4, HP was applied 3x15' with 15' between intervals; and for G5, 15% CP was applied for 120'/10 days at home. A spectrophotometer was used to measure color change before the treatment and after 24 h, 1 week, 1, 6, 12, 18 and 24 months. A VAS questionnaire was used to evaluate tooth sensitivity before the treatment, immediately following treatment, 24 h after and finally 1 week after. Results Statistical analysis did not reveal any significant differences between in-office bleaching with or without HL activation related to effectiveness; nevertheless the time required was less with HL. Statistical differences were observed between the results after 24 h, 1 week and 1, 6, 12, 18 and 24 months (intergroup). Immediately, in-office bleaching increased tooth sensitivity. The groups activated with HL required less application time with gel. Conclusion All techniques and bleaching agents used were effective and demonstrated similar behaviors. PMID:23032205

MONDELLI, Rafael Francisco Lia; de AZEVEDO, Juliana Felipi David e Góes; FRANCISCONI, Ana Carolina; de ALMEIDA, Cristiane Machado; ISHIKIRIAMA, Sérgio Kiyoshi

2012-01-01

368

Natural Infection of Pregnant Cows with Schmallenberg Virus – A Follow-Up Study  

PubMed Central

Schmallenberg virus (SBV), an orthobunyavirus discovered in European livestock in late 2011 for the first time, causes premature or stillbirth and severe fetal malformation when cows and ewes are infected during pregnancy. Therefore, cattle of two holdings in the initially most affected area in Germany were closely monitored to describe the consequence for fetuses and newborn calves. Seventy-one calves whose mothers were naturally infected during the first five months of pregnancy were clinically, virologically, and serologically examined. One calve showed typical malformation, another one, born without visible abnormalities, was dead. Two cows aborted during the studied period; spleen and brain samples or meconium swabs were tested by real-time PCR, in none of the fetuses SBV-specific RNA was detectable and the tested fetal sera were negative in a commercially available antibody ELISA. In contrast, in nine clinically healthy calves high SBV-antibody titers were measurable before colostrum intake, and in meconium swabs of six of these animals viral RNA was present as well. The mothers of all nine seropositive calves were presumably infected between days 47 and 162 of gestation, which is within the critical timeframe for fetal infection suggested for SBV and related viruses. PMID:24853555

Schirrmeier, Horst; Hoffmann, Bernd; Beer, Martin

2014-01-01

369

Use of xylitol chewing gum in daycare centers: a follow-up study in Savonlinna, Finland.  

PubMed

The use of toothbrushes in daycare centers has been questioned because of the possibility of infections spreading through unsupervised brushing. Several field studies have demonstrated a caries-preventive effect of xylitol chewing gum--a measure that could be a practical way of taking care of oral hygiene during daycare hours without brushing. A community trial was conducted in Savonlinna, Finland to test the caries-preventive effect of xylitol chewing gum at these centers. A total of 921 children were recruited. The daycare centers were randomly distributed to xylitol chewing gum or brushing groups. An additional 270 children who had not been in daycare centers were later organized into an external reference group in order to check whether the children in the daycare centers were representative of all children in Savonlinna. The results revealed a statistically significant but clinically small difference between the xylitol and brushing groups in favor of the xylitol group. Many families used the daycare services irregularly. Changes in workplace, periods of unemployment, the birth of other children in the family, etc., affect the likelihood of families keeping their children in a daycare center for many years. Despite the fact that conditions were not optimal, oral health status in the xylitol group was a little bit better than in the control group. The use of xylitol can therefore be recommended, especially if the personnel do not have the possibility to supervise the brushing. PMID:14960009

Kovari, Helena; Pienihäkkinen, Kaisu; Alanen, Pentti

2003-12-01

370

[Hepatitis in drug addicts (follow-up study with biopsies) (author's transl)].  

PubMed

Viral hepatitis, proven by biopsy in 44 patients known to be drug addicts or confirmed drug takers had serial clinical, biochemical and (half of them) biopsy studies between 1971 and 1974. At the time of the first biopsy the period of addicition averaged 28.8 months. 30 of the 44 patients had had jaundice. At the time of the last biopsy, 20 of the 44 had chronic persisting and three had chronic active hepatitis, i.e. more than half had a chronic form. A further 12 patients had "hippie" hepatitis, a special form of acute viral hepatitis with piecemeal necrosis, histological evidence of possible change to a chronic state. There was no case of complete healing during the period of observation. The high rate of chronic hepatitis is thought to be due to partially insufficient immune response. The clinical and even biochemical course in most of the patients was remarkably mild. Severe clinical forms are rare and were not observed at all in the described group. It would therefore, seem that the prognosis is generally good, in contrast to chronic hepatitis in non-addicts. PMID:1122844

Aenishänslin, H W; Stalder, G A; Bianchi, L; Gudat, F; Carmann, H

1975-04-18

371

Language development in very low birth weight preterm children: a follow-up study.  

PubMed

The language development of 17 very low birth weight (VLBW) preterm children was compared with that of matched controls at the ages of 2 and 4 years. At the age of 2 years, the VLBW preterm children achieved significantly lower scores in the language comprehension test than their matched controls. In addition, they used shorter and more immature sentences. At the age of 4 years, difficulties in the VLBW preterm children manifested as deficiencies in language comprehension, naming and auditory discrimination. The language test results at the age of 2 years significantly correlated with those at the age of 4 years, but mainly in the preterm group. The highest and most frequent correlations were found between the language test scores at 2 years and the auditory discrimination test scores at 4 years. The only significant correlation to be found in the control group was between the vocabulary test score at 2 years and the consonant discrimination test score at 4 years. Therefore, language development of the VLBW preterm children should be measured and monitored from toddler age onwards. Special attention should be paid to measurements of auditory processing. While the results of the present study, however, represent mainly the outcome in a group of VLBW preterm children with changes in the neonatal MRI, the results should not be generalized to all VLBW preterm children. PMID:15001826

Jansson-Verkasalo, E; Valkama, M; Vainionpää, L; Pääkkö, E; Ilkko, E; Lehtihalmes, M

2004-01-01

372

Neurotoxic sequelae of mercury exposure: an intervention and follow-up study in the Brazilian Amazon.  

PubMed

Since 1995, the Caruso Project used an Ecosystem Approach to Human Health to examine mercury (Hg) exposure in fish-eating communities in the Brazilian Amazon and develop interventions to maximise nutrition from traditional diet and minimise toxic risk. In 1995, 2000 and 2006, this study followed fish consumption, Hg levels, and visual and motor functions in 31 villagers. Questionnaires gathered information on socio-demographics and diet. Hair Hg (H-Hg) levels were measured. Visual acuity, colour vision, manual dexterity and grip strength were assessed. Data was analysed using general linear models of repeated measures. Total fish consumption, similar in 1995 and 2000, decreased in 2006. Carnivorous fish consumption initially decreased and then remained stable, whereas non-carnivorous fish consumption first increased and then decreased. H-Hg declined from 17.6 to 7.8 ?g/g. Visual functions showed a significant decrease over time, with those with H-Hg ? 20 ?g/g in 1995 showing greater loss. Motor functions showed initial improvement and then returned to the 1995 performance level. Decrease in Hg exposure is attributed to the intervention and socio-economic changes in the village. While there may be a certain reversibility of motor deficits, visual capacities may decrease progressively with respect to exposure prior to the intervention. PMID:22160443

Fillion, Myriam; Philibert, Aline; Mertens, Frédéric; Lemire, Mélanie; Passos, Carlos José Sousa; Frenette, Benoit; Guimarães, Jean Rémy Davée; Mergler, Donna

2011-06-01

373

A follow-up study of Eco Education's environmental service-learning program  

NASA Astrophysics Data System (ADS)

The purpose of the study is to determine student views of the influence of the Eco Education Urban Stewards program's impact on their involvement in community environmental initiatives. Eco Education is a non-profit organization in St. Paul that facilitates an urban, environmental, year-long science curriculum delivered in middle schools in Minnesota. The year-long program ends with an urban, environmental service-learning project. Ten high school students from the Inter District Downtown School who had completed Urban Stewards in middle school took a survey and were interviewed and compared with ten high school students who had a more traditional middle school science experience. Semi-structured oral interviews were conducted with each student. Transcriptions of the interviews were analyzed and compared to the survey results. The survey results were tabulated and given numerical values to compare the Eco Education and non-Eco Education students. Common themes and differences were discovered when comparing the survey results and interview transcriptions of the two groups. Urban Stewards students demonstrated more awareness of environmental issues, concerns and community projects but not by a significant amount.

Hobert, Thomas Milton

374

Inadequate Riboflavin Intake and Anemia Risk in a Chinese Population: Five-Year Follow Up of the Jiangsu Nutrition Study  

PubMed Central

Objectives Riboflavin (vitamin B2) has been shown in animal studies to affect the absorption and metabolism of iron. Cross-sectional population studies show a relationship between riboflavin intake and anemia but prospective population studies are limited. The aim of the study was to determine the relationship between riboflavin intake and the risk of anemia in a Chinese cohort. Method The study used data from 1253 Chinese men and women who participated in two waves of the Jiangsu Nutrition Study (JIN), five years apart, in 2002 and 2007. Riboflavin intake and hemoglobin (Hb) were quantitatively assessed together with dietary patterns, lifestyle, socio-demographic and health-related factors. Results At baseline, 97.2% of participants had inadequate riboflavin intake (below the estimate average requirement). Riboflavin intake was positively associated with anemia at baseline, but low riboflavin intake was associated with an increased risk of anemia at follow-up among those anemic at baseline. In the multivariate model, adjusting for demographic and lifestyle factors and dietary patterns, the relative risk and 95% confidence interval for anemia at follow-up, across quartiles of riboflavin intake were: 1, 0.82(0.54–1.23), 0.56(0.34–0.93), 0.52(0.28–0.98) (p for trend 0.021). There was a significant interaction between riboflavin and iron intake; when riboflavin intake was low, a high iron intake was associated with a lower probability of anemia at follow-up. This association disappeared when riboflavin intake was high. Conclusion Inadequate riboflavin intake is common and increases the risk of anemia in Chinese adults. Given the interaction with iron intake correcting inadequate riboflavin intake may be a priority in the prevention of anemia, and population based measurement and intervention trials are required. PMID:24533156

Shi, Zumin; Zhen, Shiqi; Wittert, Gary A.; Yuan, Baojun; Zuo, Hui; Taylor, Anne W.

2014-01-01

375

Follow-up study of the revascularization process of cryopreserved islets of Langerhans.  

PubMed

Cryopreservation of islets of Langerhans is a necessary procedure since human pancreatic islet transplantation has become a reality for the clinical treatment of Type I, insulin-dependent diabetes mellitus. Although successful cryopreservation of rodent and human islets is a well-established technique for islet storage after isolation and purification, little is known about the influence of the freeze-thaw procedure on the islets' potential to induce angiogenesis and revascularization, a major process necessary for the viability of grafted cells. In this study, the revascularization process of cryopreserved islets transplanted in the liver and in the renal subcapsular space of diabetic and nondiabetic rats is analyzed by a double indirect immunofluorescence technique. Frozen-thawed pancreatic islets were cooled slowly to -40 degrees C, stored at -196 degrees C, and thawed rapidly. Lewis rat were grafted with either Lewis (isografts) or Wistar (allografts) overnight-cultured and frozen-thawed islets obtained by collagenase digestion. Rats were killed different days after implantation, and the livers and kidneys bearing the grafted islets were snap-frozen and immunohistochemically stained with a double immunofluorescence technique using a rabbit anti-factor VIII antiserum (which labels endothelial cells) and a guinea pig anti-insulin antibody. Overnight-cultured islet grafts completed revascularization by Days 4-7 after transplantation, as shown by the detection of endothelial cells within and surrounding the islets. The identical staining pattern of revascularization was observed in islets frozen-thawed before transplantation. It is concluded that islet cryopreservation is a suitable technique for long-term storage prior to transplantation since it does not interfere with the neovascularization process of islet grafts. PMID:8893512

Mendola, J; Corominola, H; Gonzalez-Clemente, J M; Esmatjes, E; Saenz, A; Fernandez-Cruz, L; Gomis, R

1996-10-01

376

Raynaud phenomenon and mortality: 20+ years of follow-up of the Charleston Heart Study cohort  

PubMed Central

Background Raynaud phenomenon (RP) is a temporary vasoconstrictive condition that often manifests itself in the fingers in response to cold or stress. It often co-occurs with certain chronic diseases that impact mortality. Our objective was to determine whether RP has any independent association with survival. Methods From 1987–1989, a total of 830 participants of the Charleston Heart Study cohort completed an in-person RP screening questionnaire. Two definitions of RP were used: a broad definition that included both blanching (pallor) and cyanotic color changes and a narrow definition that included only blanching. All-cause and cardiovascular disease (CVD) mortality were compared between subjects with and without RP using race-specific survival models that adjusted for age, sex, baseline CVD, and 10-year risk of coronary heart disease. Results Using the narrow RP definition, we identified a significant interaction between older age and the presence of RP on all-cause mortality. In the broad RP definition model, the presence of RP was not associated with CVD mortality among blacks; however, among whites, the presence of RP was associated with a 1.6-fold increase in the hazard associated with CVD-related death (hazard ratio: 1.55, 95% confidence interval: 1.10–2.20, P=0.013). Conclusion RP was independently associated with mortality among older adults in our cohort. Among whites, RP was associated with increased CVD-related death. It is possible that RP may be a sign of undiagnosed vascular disease. PMID:25678814

Nietert, Paul J; Shaftman, Stephanie R; Silver, Richard M; Wolf, Bethany J; Egan, Brent M; Hunt, Kelly J; Smith, Edwin A

2015-01-01

377

Predictors for health improvement in patients with fibromyalgia: a 2-year follow-up study.  

PubMed

Fibromyalgia (FM) has a high impact on all aspects of health. The effect from interventions is usually small and characterized by uncertainty. Better insight in predictors for improved health is essential. The present study aimed to understand predictors for patient global impression of change and changes in overall health. Data from a longitudinal cohort of recently diagnosed FM patients (n?=?203) were used. Within this cohort, patients were pre-randomized to either a multidisciplinary (n?=?108) or an, aerobic exercise (n?=?47) program, or usual care (n?=?48). Only a limited number of patients started with the programs (n?=?86) or participated fully, i.e., attended >70 % of the scheduled sessions (n?=?68). Patients completed questionnaires covering all components of the International Classification of Functioning, Disability and Health (ICF) bio-psycho-social model of health, which was used as a framework to structure potential predictors. Principal component analysis was used to reduce the number of potential predictors. Regression analyses were used to explore associations with the outcome variables. Principal component analysis yielded five factors representing areas that covered different ICF components and chapters. "Being employed" and "full participation in a program" were independently associated with a better global impression of change. A longer duration of FM-related symptoms and more limitations in physical areas of body functions were independently associated with a worse impression of overall health. Higher levels of perceived limitations in physical and mental activities were associated with "starting to participate in a program" and with "full participation in a program." Recently diagnosed FM patients that report fewer physical limitations may experience more improvement in health if they are at work and have a positive attitude towards participating in an offered health-care intervention. These findings give support to an active rather than to a care-avoiding attitude of health-care workers in their contacts to these patients. PMID:23975362

van Eijk-Hustings, Yvonne; Kroese, Mariëlle; Boonen, Annelies; Bessems-Beks, Monique; Landewé, Robert

2015-01-01

378

Human-Grey parrot (Psittacus erithacus) reciprocity: a follow-up study.  

PubMed

In a previous study (Péron et al. in Anim Cogn, doi: 10.1007/s10071-012.05640 , 2012), Grey parrots, working in dyads, took turns choosing one of four differently coloured cups with differing outcomes: empty (null, non-rewarding), selfish (keeping reward for oneself), share (sharing a divisible reward), or giving (donating reward to other). When the dyads involved three humans with different specific intentions (selfish, giving, or copying the bird's behaviour), birds' responses only tended towards consistency with human behaviour. Our dominant bird was willing to share a reward with a human who was willing to give up her reward, was selfish with the selfish human, and tended towards sharing with the copycat human; our subordinate bird tended slightly towards increased sharing with the generous human and selfishness with the selfish human, but did not clearly mirror the behaviour of the copycat. We theorized that the birds' inability to understand the copycat condition fully-that they could potentially maximize reward by choosing to share-was a consequence of their viewing the copycat's behaviour as erratic compared with the consistently selfish or giving humans and thus not realizing that they were indeed being mirrored. We suggested that copycat trials subsequently be performed as a separate experiment, without being contrasted with trials in which humans acted consistently, in order to determine if results might have differed. We have now performed that experiment, and shown that at least one Grey parrot--our dominant--responded in a manner suggesting that he deduced the appropriate contingencies. PMID:24474186

Péron, Franck; Thornburg, Luke; Thornberg, Luke; Gross, Brya; Gray, Suzanne; Pepperberg, Irene M

2014-07-01

379

New follow-up study of the atmosphere of GJ1214b  

NASA Astrophysics Data System (ADS)

GJ1214b is an extremely interesting 6.55Mearth and 2.6 Earth radii sub-Neptune planet orbiting a M-dwarf host. Its proximity, only 14pc, makes it an excellent target for studies of exoplanetary atmospheres (Charbonneau et al. 2009). Furthermore, the sub-Neptunes/Super Earth-sized planets are only one step between Jupiter-sized and habitable Earth-sized planets with a biosphere. Due to favorable parameters of GJ1214 system, we posses great coverage of many wavelengths in planetary transmission spectra from optical to NIR regions (Miller-Ricci & Fortney 2009). However, the scenarios for the atmospheric compositions are still open. Based on the available measurements, the solar composition (hydrogen rich) atmosphere can be most probably ruled out. That is given by fact that we observe rather a flat spectrum than the absorption features in the hydrogen rich model. Thus, currently more plausible models are atmosphere composed of heavy elements such as water or atmosphere covered by clouds (Bean, Desert, Kabath et al. 2011). Here, we present our spectrophotometric and photometric measurements obtained with SOI and OSIRIS instruments (both SOAR telescope) and SOFI (ESO NTT). We observed 5 transit events of GJ1214b and determined the Rp/Rs ratios for every measured wavelength (Caceres, Kabath, Hoyer et al. 2013). Our photometric measurements at 0.8 micron (Bessel-I) and at 2.14 micron (NIR narrow band) correlate with the flat transmission spectrum, therefore strongly supporting the water or cloudy atmosphere. Our spectrophotometric measurements in the H+K region do not posses the sufficient precision in the Rp/Rs ratios. We conclude that the hydrogen rich model is less probable. However, to be able to decide if the planetary atmosphere is hidden in clouds or if we encountered a water world, we still need more measurements with extremely high accuracy. Here, literally, every new point counts. Finally, we would like to present preliminary results obtained from our 2013 campaign focused at another small exoplanet GJ436b as a demonstration of potential and limitations for ground based transmission spectroscopy.

Kabath, P.; Cáceres, C.; Hoyer, S.; Ivanov, V. D.; Rojo, P.; Girard, J. H.; Kempton, E. M.-R.; Fortney, J. J.; Minniti, D.

2014-03-01

380

Follow-up study on lead exposure in children living in a smelter community in northern Mexico  

Microsoft Academic Search

Background  To study the changes of children lead exposure in the city of Torreon during the last five years, after environmental and\\u000a public health interventions, using the timeline of lead in blood concentration as the biomarker of exposure and its relation\\u000a to lead in soil concentrations.\\u000a \\u000a \\u000a \\u000a \\u000a Methods  This follow-up study started in 2001 and consisted of 232 children living in nine neighborhoods

Marisela Rubio-Andrade; Francisco Valdés-Pérezgasga; J Alonso; Jorge L Rosado; Mariano E Cebrián; Gonzalo G García-Vargas

2011-01-01

381

Follow-Up Testing  

Cancer.gov

Provides possible follow-up testing, next steps and treatments for women who receive abnormal cervical screening test results, including estrogen cream, colposcopy, endocervical curettage biopsy, punch biopsy, and cone biopsy.

382

Mortality and incidence of cancer in a cohort of Swedish chimney sweeps: an extended follow up study.  

PubMed

Despite 200 years of efforts to regulate safety in this occupation, chimney sweeps have increased mortality from cancer, ischaemic heart disease, and respiratory disease. Mortality and incidence of cancer were examined in a cohort of 5542 Swedish chimney sweeps employed through their national trade union at any time between 1918 and 1980. Previous studies of this cohort found increased risks of ischaemic heart disease, respiratory disease, accidental deaths, and various neoplasms. By increasing follow up, we sought to increase the power of the study and examine disease time trends. Mortality analysis was extended 7.5 years to cover the period 1951-90; cancer incidence analysis was extended six years to cover the period 1958-87. New findings include increased incidence and mortality of prostate cancer (SMR 169, 95% CI 106-256, 22 observed) and increased incidence of total haematolymphatic cancers (SIR 151, 95% CI 106-209, 36 observed). When only the most recent follow up period was analysed, previously observed risks persisted for total lung cancer (SIR 178, 95% CI 99-293), oat cell lung cancer (SIR 240, 95% CI 103-472), bladder cancer (SIR 247, 95% CI 131-422), and oesophageal cancer (Obs/Exp = 2/1.1). Mortality from ischaemic heart disease (SMR 98, 95% CI 76-123) and respiratory disease (SMR 111, 95% CI 56-199) declined during recent follow up, although significant excess mortality remained during analysis of the entire study period (ischaemic heart disease SMR 128, 95% CI 112-145; respiratory disease SMR 159, 95% CI 115-213). In analyses of the entire study period, risks of ischaemic heart disease and lung, bladder, and oesophageal cancer were adjusted for smoking; oesophageal cancer was also adjusted for use of alcohol. All risks remained significantly raised. Exposure-response analyses showed significant positive associations between duration of employment and risks for mortality from lung, oesophageal, and total cancer. Chimney sweeps remain at increased risk for cancers of the lung, oesophagus, and bladder. Our study supports a casual role for exposure to chimney soot, which contains carcinogens including polycyclic aromatic hydrocarbons. Extended follow up of this cohort now shows increased risks of prostate and haematolymphatic cancers. PMID:8507598

Evanoff, B A; Gustavsson, P; Hogstedt, C

1993-05-01

383

EXTREMITY SARCOMA SURGERY IN YOUNGER CHILDREN: TEN YEARS OF PATIENTS TEN YEARS AND UNDER  

PubMed Central

Sarcoma surgeons face unique challenges in younger patients with significant skeletal growth remaining. The heightened concerns regarding radiation in the very young and the drastic changes expected in the lengths and cross-sectional areas of bones affect the decision-making for both soft-tissue and bone sarcomas in this population. Nonetheless, there is sparse literature focused on sarcoma surgery in this age group. The records of one tertiary regional sarcoma treatment program were reviewed to identify all patients ten years old or younger at the time of local control surgery for limb or limb-girdle sarcomas. Demographic information, diagnosis, surgery performed, complications, and general outcomes were gleaned from the medical records. 43 patients were identified, including 15 with osteosarcomas, 11 Ewing’s sarcoma family tumors, five rhabdomyosarcomas, and two synovial sarcomas, among others. Location of tumors varied widely, but demonstrated a predilection for the upper extremity more than is typical in adolescents with the same tumor types. Survival was favorable overall, with only five patients dying from disease. Most patients continued to function well at latest follow-up, but 16 experienced additional surgical interventions following the index procedure. Sarcoma surgery in the younger growing child presents challenges for the surgeon, patient, and parents, but is usually successful in the long-term. PMID:22096434

Israelsen, Ryan B; Ilium, Benjamin E; Crabtree, Susie; Randall, R Lor; Jones, Kevin B

2011-01-01

384

Adherence to International Follow-Up Guidelines in Type 2 Diabetes: A Longitudinal Cohort Study in Luxembourg  

PubMed Central

Introduction Type 2 diabetes is associated with severe micro- and macro-vascular complications. Physicians’ and patients’ adherence to follow-up guidelines permits postponing or reducing these complications. The objectives were to assess the level of adherence to fundamental follow-up guidelines and determine patients’ characteristics associated with this level of adherence in the context of Luxembourg, where no guidelines were implemented. Study population The exhaustive residing population treated for type 2 diabetes in Luxembourg during the 2000-2006 period (N?=?21,068). Methods Seven fundamental criteria were extracted from international guidelines (consultation with the treating physician, HbA1c tests, electrocardiogram, retinal, dental, lipid and renal check-ups). The factors associated with the level of adherence to those criteria were identified using a partial proportional odds model. Results In 2006, despite 90% of the patients consulted at least 4 times their treating physician, only 0.6% completed all criteria; 55.0% had no HbA1c test (?8.6 points since 2000) and 31.1% had a renal check-up (+21.6 points). The sex (ORmale: 0.87 [95%CI, 0.83?0.92]), the nationality (ORNonEU: 0.64 [0.52?0.78]), the type of antidiabetic treatment (ORoral: 1.48 [1.35?1.63], ORmixed: 1.35 [1.20?1.52]) and the type of treating physician (ORG-ID: 0.47 [0.42?0.53]) were the main factors associated with the level of adherence in 2006 (3 or more criteria). Conclusion A large percentage of patients were not provided with a systematic annual follow-up between 2000 and 2006. This study highlighted the necessity to promote guidelines in Luxembourg, education for physicians and to launch a national discussion on a disease management program for diabetic patients. PMID:24244637

Renard, Laurence M.; Bocquet, Valery; Vidal-Trecan, Gwenaelle; Lair, Marie-Lise; Blum-Boisgard, Claudine

2013-01-01

385

Follow-up study on lead exposure in children living in a smelter community in northern Mexico  

PubMed Central

Background To study the changes of children lead exposure in the city of Torreon during the last five years, after environmental and public health interventions, using the timeline of lead in blood concentration as the biomarker of exposure and its relation to lead in soil concentrations. Methods This follow-up study started in 2001 and consisted of 232 children living in nine neighborhoods in Torreon. Children were tested at 0, 6, 12 and 60 months. Lead in blood concentrations, Hemoglobin, Zinc-Protoporphyrin, anthropometric measures and socioeconomic status questionnaire was supplied to the parents. Results Median and range of lead in blood concentrations obtained at 0, 6, 12, 60 months were: 10.12 ?g/dl (1.9 - 43.8), 8.75 ?g/dl (1.85 - 41.45), 8.4 ?g/dl (1.7 - 35.8) and 4.4 ?g/dl (1.3 - 30.3), respectively. The decrease of lead in blood levels was significantly related to ages 0, 6, 12 and 60 months of the follow-up study. The timeline of B-Pb was associated with the timeline of lead in soil concentrations. Conclusions B-Pb levels have significantly decreased in the group of children studied. This could be explained by a) environmental interventions by authorities and the smelter companies, b) normal changes in hygienic habits as children age and c) lead redistribution from blood to hard tissues. PMID:21767395

2011-01-01

386

Goal-related outcome after acute alcohol-pancreatitis -- a two-year follow-up study.  

PubMed

The aim of this study was to find out if an acute pancreatitis leads the patients to reduce their alcohol consumption and if there are factors predicting the outcome. We also observed which factors affected the choice of patient's personal drinking goal, e.g., abstinence or moderate drinking, how this goal changed during the follow-up and how the goal affected the change in drinking habits. In 2001-2005, 120 patients treated in Tampere University Hospital for their first alcohol-related acute pancreatitis were interviewed before discharge from the hospital and at the two-year follow-up. All patients had at least one intervention session for their alcohol use. Of the patients 87 (72.5%) completed the study. The alcohol consumption level and its changes, personal drinking goal of the patients, the factors affecting the choice and the changes of the goal were observed. Most (96.4%) of the patients were willing to reduce their drinking. At follow-up, 34 (40.5%) patients succeeded in reducing their alcohol consumption under the pre-set moderate drinking level. The only factor predicting alcohol use was the number of hospitalization days due to the acute alcohol-related pancreatitis (p=0.015). Those who chose abstinence seemed to succeed more often in stopping drinking or reducing their drinking below risk levels as compared to those with moderation goal (47.9% vs. 28.6%, p=0.075). The only abstinence-goal predicting factor was the concern of the relatives, friends or doctors (p=0.001). All 6 patients who needed intensive care chose abstinence-goal. During the follow-up period the goal changed. At baseline, the majority chose abstinence but two years after pancreatitis, the majority was striving for moderate drinking. A serious illness seems to be a good opportunity to change and to motivate patients. Even if abstinence is recommended to patients with alcohol-related pancreatitis, communication of individual goals is important in the motivation process of the patients. PMID:24018221

Lappalainen-Lehto, Riitta; Koistinen, Noora; Aalto, Mauri; Huhtala, Heini; Sand, Juhani; Nordback, Isto; Seppä, Kaija

2013-12-01

387

STOPPIT Baby Follow-Up Study: The Effect of Prophylactic Progesterone in Twin Pregnancy on Childhood Outcome  

PubMed Central

Objectives To determine the long-term effects of in utero progesterone exposure in twin children. Methods This study evaluated the health and developmental outcomes of all surviving children born to mothers who participated in a double-blind, placebo-controlled trial of progesterone given for the prevention of preterm birth in twin pregnancies (STOPPIT, ISRCTN35782581). Follow-up was performed via record linkage and two parent-completed validated questionnaires, the Child Development Inventory and the Health Utilities Index. Results Record linkage was successfully performed on at least one record in 759/781 (97%) children eligible for follow-up. There were no differences between progesterone-exposed and placebo-exposed twins with respect to incidence of death, congenital anomalies and hospitalisation, nor on routine national child health assessments. Questionnaire responses were received for 324/738 (44%) children. The mean age at questionnaire follow-up was 55.5 months. Delay in at least one developmental domain on the Child Development Inventory was observed in 107/324 (33%) children, with no evidence of difference between progesterone-exposed and placebo-exposed twins. There was no evidence of difference between the progesterone and placebo groups in global health status assessed using the Health Utilities Index: 89% of children were rated as having ‘excellent’ health and a further 8% as having ‘very good’ health. Conclusions In this cohort of twin children there was no evidence of a detrimental or beneficial impact on health and developmental outcomes at three to six years of age due to in utero exposure to progesterone. PMID:25881289

McNamara, Helen Christine; Wood, Rachael; Chalmers, James; Marlow, Neil; Norrie, John; MacLennan, Graeme; McPherson, Gladys; Boachie, Charles; Norman, Jane Elizabeth

2015-01-01

388

Cancer mortality following cardiac catheterization: a preliminary follow-up study on 4,891 irradiated children  

SciTech Connect

A retrospective cohort study was conducted on the risk of radiation-induced cancer mortality following cardiac catheterization. The study included 4,891 children with congenital heart disease who were assessed by cardiac catheterization during 1946 to 1968 at The Hospital for Sick Children, Toronto. The cohort was matched against the Ontario cancer death file from 1950 to 1975. The average period of follow-up was 13 years and more than 66,000 person-years have been accrued from the cohort. No deaths from breast cancer or thyroid cancer were identified. Five cancer deaths were observed and compared with 4.8 expected deaths based on Ontario cancer death rates. The five cancer deaths resulted from three leukemias, one Wilms tumor, and one unspecified nervous system tumor. The preliminary findings did not demonstrate a significant leukemia risk arising from diagnostic cardiac catheterizations. Continued follow-up of this cohort is required to evaluate the risk of breast and thyroid cancers which can occur more than 20 years following radiation exposure.

Spengler, R.F.; Cook, D.H.; Clarke, E.A.; Olley, P.M.; Newman, A.M.

1983-02-01

389

Cancer mortality following cardiac catheterization: a preliminary follow-up study on 4,891 irradiated children  

SciTech Connect

A retrospective cohort study was conducted on the risk of radiation-induced cancer mortality following cardiac catheterization. The study included 4,891 children with congenital heart disease who were assessed by cardiac catheterization during 1946 to 1968 at The Hospital for Sick Children, Toronto. The cohort was matched against the Ontario cancer death file from 1950 to 1975. The average period of follow-up was 13 years and more than 66,000 person-years have been accrued from the cohort. No deaths from breast cancer or thyroid cancer were identified. Five cancer deaths were observed and compared with 4.8 expected deaths based on Ontario cancer death rates. The five cancer deaths resulted from three leukemias, one Wilms' tumor, and one unspecified nervous system tumor. The preliminary findings did not demonstrate a significant leukemia risk arising from diagnostic cardiac catheterizations. Continued follow-up of this cohort is required to evaluate the risk of breast and thyroid cancers which can occur more than 20 years following radiation exposure.

Spengler, R.F.; Cook, D.H.; Clarke, E.A.; Olley, P.M.; Newman, A.M.

1983-02-01

390

Effectiveness of Outreach Program: A Three Year Follow-Up Study Among 12 Years School Students in Lucknow  

PubMed Central

Aim: To assess the effectiveness of outreach program in the 12 years school going children during a three year follow up period of Lucknow city. Materials and Methods: A random sample of 298 school going children of age 12 years was drawn from adopted schools of Lucknow. Three years later the same population was re-examined with a population of 242 children of 15 y age group. The oral health status of these children was accessed by using WHO 1997 profoma. Results: Significantly (p<0.001) higher proportion of children had healthy gingival, healthy periodontal status after three years. The difference in regard to crowding in the incisal segment in 2010 and 2013 was statistically highly significant (p<0.001). Conclusion: The findings of the study showed that after providing regular dental check up and treatment camps in the three adopted schools after three year follow up study from 2010-2013 showed positive impact on the children oral hygiene status and has been estimated to be on the more positive aspect in future also. PMID:25738083

Pawar, Harshita; Saha, Sabyasachi; Jagannath, GV; Kumari, Minti; Singh, Ekta

2015-01-01

391

Genetic Susceptibility to Type 2 Diabetes and Obesity: Follow-Up of Findings from Genome-Wide Association Studies  

PubMed Central

Elucidating the underlying genetic variations influencing various complex diseases is one of the major challenges currently facing clinical genetic research. Although these variations are often difficult to uncover, approaches such as genome-wide association studies (GWASs) have been successful at finding statistically significant associations between specific genomic loci and disease susceptibility. GWAS has been especially successful in elucidating genetic variants that influence type 2 diabetes (T2D) and obesity/body mass index (BMI). Specifically, several GWASs have confirmed that a variant in transcription factor 7-like 2 (TCF7L2) confers risk for T2D, while a variant in fat mass and obesity-associated protein (FTO) confers risk for obesity/BMI; indeed both of these signals are considered the most statistically associated loci discovered for these respective traits to date. The discovery of these two key loci in this context has been invaluable for providing novel insight into mechanisms of heritability and disease pathogenesis. As follow-up studies of TCF7L2 and FTO have typically lead the way in how to follow up a GWAS discovery, we outline what has been learned from such investigations and how they have implications for the myriad of other loci that have been subsequently reported in this disease context. PMID:24719615

Basile, Kevin J.; Johnson, Matthew E.; Xia, Qianghua; Grant, Struan F. A.

2014-01-01

392

Longitudinal associations of obesity with affective disorders and suicidality in the Baltimore epidemiologic catchment area follow-up study.  

PubMed

Our aim was to examine the longitudinal associations between obesity and mental health variables (psychiatric diagnoses and suicidal behaviors). Data were from waves 3 and 4 of the Baltimore Epidemiologic Catchment Area study (N = 1071). Participants were aged 30 to 86 years at wave 3 (mean, 47.6 years; SD, 12.8). The prevalence of obesity increased from 27.6% to 39.1% during the follow-up. Logistic regression analyses revealed no associations between baseline obesity and onset of mental disorders or suicidal behaviors between waves 3 and 4 in fully adjusted models; however, baseline obesity predicted new-onset suicide attempts in models adjusted for sociodemographics and mental disorders. Baseline depression predicted weight gain during the 11-year follow-up period (F = 4.014, p < 0.05), even after controlling for important confounders. Overall, most mental health variables were not associated with obesity, suggesting that clinicians and others should be wary of "weight-ism" and avoid making the assumption that higher body weight relates to mental health problems. PMID:24727724

Henriksen, Christine A; Mather, Amber A; Mackenzie, Corey S; Bienvenu, Oscar Joseph; Sareen, Jitender

2014-05-01

393

Contribution of deaths related to alcohol use of socioeconomic variation in mortality: register based follow up study.  

PubMed Central

OBJECTIVE: To estimate the contribution of excessive alcohol use to socioeconomic variation in mortality among men and women in Finland. DESIGN: Register based follow up study. SUBJECTS: The population covered by the 1985 and 1990 censuses, aged > or = 20 in the follow up period 1987-93. MAIN OUTCOME MEASURES: Total mortality and alcohol related mortality from all causes, from diseases, and from accidents and violence according to socioeconomic position. The excess mortality among other classes compared with upper non-manual employees and differences in life expectancy between the classes were used to measure mortality differentials. RESULTS: Alcohol related mortality constituted 11% of all mortality among men aged > or = 20 and 2% among women and was higher among manual workers than among other classes. It accounted for 14% of the excess all cause mortality among manual workers over upper non-manual employees among men and 4% among women and for 24% and 9% of the differences in life expectancy, respectively. Half of the excess mortality from accidents and violence among male manual workers and 38% among female manual workers was accounted for by alcohol related deaths, whereas in diseases the role of alcohol was modest. The contribution of alcohol related deaths to relative mortality differentials weakened with age. CONCLUSIONS: Class differentials in alcohol related mortality are an important factor in the socioeconomic mortality differentials in Finland, especially among men, among younger age groups, and in mortality from accidents and violence. PMID:9253268

Mäkelä, P.; Valkonen, T.; Martelin, T.

1997-01-01

394

Follow-up MRI study of the insular cortex in first-episode psychosis and chronic schizophrenia.  

PubMed

Morphologic abnormalities of the insular cortex have been described in psychotic disorders such as schizophrenia, but it remains unknown whether these abnormalities develop progressively over the course of the illness. In the current study, longitudinal magnetic resonance imaging data were obtained from 23 patients with first-episode psychosis (FEP), 11 patients with chronic schizophrenia, and 26 healthy controls. The volumes of the short (anterior) and long (posterior) insular cortices were measured on baseline and follow-up (between 1 and 4 years later) scans and were compared across groups. In cross-sectional comparison at baseline, the FEP and chronic schizophrenia patients had significantly smaller short insular cortex than did controls. In longitudinal comparison, the FEP patients showed significant gray matter reduction of the insular cortex over time (-4.3%/2.0 years) compared with controls (0.3%/2.2 years) without significant subregional effects, but there was no difference between chronic schizophrenia patients (-1.7%/2.4 years) and controls. The gray matter loss of the left insular cortex over time in FEP patients was correlated with the severity of positive and negative symptoms at follow-up. These findings indicate that patients with psychotic disorders have smaller gray matter volume of the insular cortex especially for its anterior portion (short insula) at first expression of overt psychosis, but also exhibit a regional progressive pathological process of the insular cortex during the early phase after the onset, which seems to reflect the subsequent symptomatology. PMID:19171466

Takahashi, Tsutomu; Wood, Stephen J; Soulsby, Bridget; McGorry, Patrick D; Tanino, Ryoichiro; Suzuki, Michio; Velakoulis, Dennis; Pantelis, Christos

2009-03-01

395

Environmental factors related to the outcome of panic disorder. A seven-year follow-up study.  

PubMed

The purpose of this study was to examine factors related to the outcome of naturalistically treated panic disorder. In order to achieve this we followed up 69 patients 7 years after they had presented at a psychiatric clinic. At follow-up, the patients were generally doing well despite persisting symptoms. Patients who were more severely ill at the time of initial assessment had a worse outcome. These patients had more severe panic and agoraphobic symptoms, had illnesses of longer duration, and more often had histories of major depression. Among the developmental variables examined, separation from a parent by death or divorce was strongly related to poor outcome. Other factors associated with poor outcome included high interpersonal sensitivity, low social class, and unmarried marital status. The findings show that, for this chronic illness, measures of severity and chronicity predict more severe and persisting symptoms. They also indicate that outcome is importantly related to the social environment in which the illness develops and with which it interacts. PMID:8245920

Noyes, R; Clancy, J; Woodman, C; Holt, C S; Suelzer, M; Christiansen, J; Anderson, D J

1993-09-01

396

Acute fatty liver of pregnancy: Over six months follow-up study of twenty-five patients  

PubMed Central

AIM: To evaluate the prognosis of patients with acute fatty liver of pregnancy (AFLP) 6 mo or longer after discharge. METHODS: The records of pregnant patients diagnosed with AFLP at Beijing Ditan Hospital over a 16-year period were reviewed in November 2012. Patients were monitored using abdominal ultrasound, liver and kidney functions, and routine blood examination. RESULTS: A total of 42 patients were diagnosed with AFLP during the study period, and 25 were followed. The mean follow-up duration was 54.5 mo (range: 6.5-181 mo). All patients were in good physical condition, but one patient had gestational diabetes. The renal and liver functions normalized in all patients after recovery, including in those with pre-existing liver or kidney failure. The ultrasound findings were normal in 12 patients, an increasingly coarsened echo-pattern and increased echogenicity of the liver in 10 patients, and mild to moderate fatty liver infiltration in 3 patients. Cirrhosis or liver nodules were not observed in any patient. CONCLUSION: Acute liver failure and acute renal failure in AFLP patients is reversible. Patients do not require any specific long-term follow-up after recovery from AFLP if their liver function tests have normalized and they remain well. PMID:25684961

Xiong, Hao-Feng; Liu, Jing-Yuan; Guo, Li-Min; Li, Xing-Wang

2015-01-01

397

Ten years of MODIS land surface phenology  

NASA Astrophysics Data System (ADS)

Green leaf phenology, the study of seasonal leaf development, senescence and abscission, is known to be an indicator of climate change. Most studies based upon remote sensing, field studies and atmospheric CO2 measurements suggest a changing climate will lead to an earlier spring onset and longer growing season. These changes in phenology have important implications for ecosystem function and biosphere-atmosphere interactions. Phenological variability directly affects year-to-year variability in many aspects of land-atmosphere interactions, in particular carbon and water cycling, along with atmospheric boundary layer properties and dynamics. Despite the direct impact of phenology on ecosystem function, recent studies have shown that terrestrial biosphere models are typically unable to adequately explain the observed interannual variability in deciduous canopy phenology and associated lagged effects. Given the synoptic overview of satellite remote sensing data across both across space and time, remote sensing data is instrumental to understanding phenology at both landscape and global scales. In the current presentation, we give an overview of ten years of land surface phenology anomalies for Northern America, using the Moderate Resolution Imaging Spectroradiometer (MODIS) phenology product. Focusing on anomalous phenological variability, we assess the ability of the MODIS phenology product to successfully capture differences in phenological regimes due to topography, or natural disturbances such as a late spring frost. We elucidate the driving forces behind these anomalies and examine possible implications in terms of carbon cycling and sequestration. The presented results therefore are prime candidates to further optimize and validate current day terrestrial biosphere models.

Hufkens, K.; Keenan, T. F.; Friedl, M.

2012-04-01

398

Aortic stiffness studies in children with Kawasaki disease: preliminary results from a follow-up study from North India.  

PubMed

Kawasaki disease (KD) is an acute medium vessel vasculitis seen in children. Coronary artery abnormalities are the most notable long-term complications. Intravenous immunoglobulin therapy has led to significant reduction in incidence of coronary aneurysms. However, higher risk of cardiovascular disease has been noted even in those children who have never been reported to develop coronary artery aneurysms during the subacute phase. Noninvasive estimation of this cardiovascular risk is useful in initiating timely preventive strategies. Arterial stiffness has been shown to be an independent predictor of cardiovascular events in general population. This study was aimed at measuring abdominal aorta stiffness in a cohort of children with KD from North India. Thirty children diagnosed to have KD at least 5 years prior to enrollment were evaluated by echocardiography for cardiac and abdominal aorta studies. Electrocardiographs were done in all patients for QT dispersion. There was a noticeable trend toward lower aortic strain, higher pressure strain elastic modulus and normalized pressure strain elastic modulus in children in the study group, though this difference did not reach statistical significance. Mean corrected QT dispersion was significantly higher in cases compared with controls. On cardiac evaluation, none of the subjects had any residual coronary artery involvement. A trend toward lower distensibility and higher stiffness of abdominal aorta was seen in cases compared with controls, though it was not found to be statistically significant. This could be a predictor of premature atherosclerosis in long term. Significantly higher QT dispersion was seen in cases compared with controls. More multicentric studies with larger sample size and longer follow-up periods are needed to clarify this issue. PMID:24696188

Gupta, Anand; Singh, Surjit; Gupta, Anju; Suri, Deepti; Rohit, Manojkumar

2014-10-01

399

Brief Report: The KIDSCREEN Follow-Up Study on Health-Related Quality of Life (HRQoL) in Spanish Children and Adolescents. Pilot Test and Representativeness  

ERIC Educational Resources Information Center

The Spanish KIDSCREEN follow-up study reassessed the Spanish baseline sample (n = 840) of the European KIDSCREEN study 3 years later (2006). The aims of this paper were to describe the KIDSCREEN follow-up study and the pilot test, and to analyze participation rates and representativeness. Instruments included the KIDSCREEN-52 HRQoL measure and a…

Palacio-Vieira, J. A.; Villalonga-Olives, E.; Alonso, J.; Valderas, J. M.; Herdman, M.; Espallargues, M.; Berra, S.; Rajmil, L.

2010-01-01

400

Total knee arthroplasty with retention of both cruciate ligaments. A 9 to 11 year follow-up study  

Microsoft Academic Search

This is a prospective assessment of 163 total knee arthroplasties in 130 patients with the retention of both cruciate ligaments of which 107 knees in 89 patients have been followed for ten years. The patients were 34 men and 96 women whose average age, at the time of the index arthroplasty, was 67 years (range: 40 to 84 years). The

J. M. Cloutier; P. Sabouret; A. Deghrar

2001-01-01

401

Oral contraceptive use and mortality after 36 years of follow-up in the Nurses’ Health Study: prospective cohort study  

PubMed Central

Objective To determine whether use of oral contraceptives is associated with all cause and cause specific mortality. Design Prospective cohort study. Setting Nurses’ Health Study, data collected between 1976 and 2012. Population 121?701 participants were prospectively followed for 36 years; lifetime oral contraceptive use was recorded biennially from 1976 to 1982. Main outcome measures Overall and cause specific mortality, assessed throughout follow-up until 2012. Cox proportional hazards models were used to calculate the relative risks of all cause and cause specific mortality associated with use of oral contraceptives. Results In our population of 121?577 women with information on oral contraceptive use, 63?626 were never users (52%) and 57?951 were ever users (48%). After 3.6 million person years, we recorded 31?286 deaths. No association was observed between ever use of oral contraceptives and all cause mortality. However, violent or accidental deaths were more common among ever users (hazard ratio 1.20, 95% confidence interval 1.04 to 1.37). Longer duration of use was more strongly associated with certain causes of death, including premature mortality due to breast cancer (test for trend P<0.0001) and decreased mortality rates of ovarian cancer (P=0.002). Longer time since last use was also associated with certain outcomes, including a positive association with violent or accidental deaths (P=0.005). Conclusions All cause mortality did not differ significantly between women who had ever used oral contraceptives and never users. Oral contraceptive use was associated with certain causes of death, including increased rates of violent or accidental death and deaths due to breast cancer, whereas deaths due to ovarian cancer were less common among women who used oral contraceptives. These results pertain to earlier oral contraceptive formulations with higher hormone doses rather than the now more commonly used third and fourth generation formulations with lower estrogen doses. PMID:25361731

Charlton, Brittany M; Rich-Edwards, Janet W; Colditz, Graham A; Missmer, Stacey A; Rosner, Bernard A; Hankinson, Susan E; Speizer, Frank E

2014-01-01

402

Residual Sleep Disturbances in Patients Remitted From Major Depressive Disorder: A 4-Year Naturalistic Follow-up Study  

PubMed Central

Study Objectives: To investigate the prevalence and clinical, psychosocial, and functional correlates of residual sleep disturbances in remitted depressed outpatients. Design: A 4-yr prospective observational study in a cohort of psychiatric outpatients with major depressive disorder was conducted with a standardized diagnostic psychiatric interview and a packet of questionnaires, including a sleep questionnaire, Hospital Anxiety and Depression Scale, NEO personality inventory, and Short Form-12 Health Survey. Settings: A university-affiliated psychiatric outpatient clinic. Interventions: N/A Measurements and Results: Four hundred twenty-one depressed outpatients were recruited at baseline, and 371 patients (mean age 44.6 ± 10.4 yr, female 81.8%; response rate 88.1%) completed the reassessments, in which 41% were classified as remitted cases. One year prevalence of frequent insomnia at baseline and follow-up in remitted patients was 38.0% and 19.3%, respectively. One year prevalence of frequent nightmares at baseline and follow-up was 24.0% and 9.3%, respectively. Remitted patients with residual insomnia were more likely to be divorced (P < 0.05) and scored higher on the anxiety subscale (P < 0.05). Remitted patients with residual nightmares were younger (P < 0.05) and scored higher on neuroticism (P < 0.05) and anxiety subscales (P < 0.01). Residual insomnia and nightmares were associated with various aspects of impaired quality of life. Residual nightmares was associated with suicidal ideation (odds ratio = 8.40; 95% confidence interval 1.79-39.33). Conclusions: Residual sleep disturbances, including insomnia and nightmares, were commonly reported in remitted depressed patients with impaired quality of life and suicidal ideation. A constellation of psychosocial and personality factors, baseline sleep disturbances, and comorbid anxiety symptoms may account for the residual sleep disturbances. Routine assessment and management of sleep symptoms are indicated in the integrated management of depression. Citation: Li SX; Lam SP; Chan JWY; Yu MWM; Wing YK. Residual sleep disturbances in patients remitted from major depressive disorder: a 4-year naturalistic follow-up study. SLEEP 2012;35(8):1153-1161. PMID:22851811

Li, Shirley X.; Lam, Siu P.; Chan, Joey W. Y.; Yu, Mandy W. M.; Wing, Yun-Kwok

2012-01-01

403

Skin cancer in patients with psoriasis treated with coal tar. A 25-year follow-up study  

SciTech Connect

For many years, crude coal tar has been used for the treatment of psoriasis. The possible carcinogenic effect of crude coal tar and ultraviolet (UV) radiation (Goeckerman regimen), considered individually or in combination, has been of some concern to physicians. A 25-year follow-up study was completed on 280 patients with psoriasis who were hospitalized and treated with crude coal tar and UV radiation at the Mayo Clinic, Rochester, Minn, during the years 1950 through 1954. The results of this study suggest that the incidence of skin cancer is not appreciably increased above the expected incidence for the general population when patients are treated with coal tar ointments. It seems that the Goeckerman regimen (topical crude coal tar combined with UV radiation) can be used with minimal risk for skin cancer in the treatment of psoriasis.

Pittelkow, M.R.; Perry, H.O.; Muller, S.A.; Maughan, W.Z.; O'Brien, P.C.

1981-08-01

404

NHEXAS PHASE I ARIZONA STUDY--STANDARD OPERATING PROCEDURE FOR CLEANING: FOLLOW UP QUESTIONNAIRE (UA-D-22.0)  

EPA Science Inventory

The purpose of this SOP is to define the steps involved in cleaning the electronic data generated from data entry of the Follow Up Questionnaire. It applies to electronic data corresponding to the Follow Up Questionnaire that was scanned and verified by the Data Staff during the...

405

Personality and the risk of cancer: a 16-year follow-up study of the GAZEL cohort  

PubMed Central

Objective Large-scale prospective studies do not support an association between neuroticism and extroversion with cancer incidence. However, research on other personality constructs is inconclusive. This longitudinal study examined the associations between four personality measures, Type 1 “suppressed emotional expression,” Type 5 “rational/anti-emotional,” hostility and Type A with cancer incidence. Methods Personality measures were available for 13,768 members in the GAZEL cohort study (baseline assessment in 1993). Follow-up for diagnoses of primary cancers was obtained from January 1, 1994 to December 31, 2009. Associations between personality and cancer incidence were evaluated using Cox proportional hazards analyses and adjusted for potential confounders. Results During a median follow-up of 16.0 years [range: 9 days-16 years], 1,139 participants received at least one diagnosis of primary cancer. The mean duration between baseline and cancer diagnosis was 9.3 years. Type 1 personality was associated with a decreased risk of breast cancer [hazard ratio (HR) per standard deviation: 0.81, 95% confidence interval (CI) = 0.68–0.97, p=.02]. Type 5 personality was not associated with prostate, breast, colorectal or smoking-related cancers, but was associated with other cancers (HR per standard deviation: 1.17, 95% CI = 1.04–1.31, p=.01). Hostility was associated with an increased risk of smoking-related cancers, which was explained by smoking habits, and Type A was not associated with any of the cancer end-points. Conclusions Several personality measures were prospectively associated with the incidence of selected cancers. These links may warrant further epidemiological studies and investigations about potential biobehavioral mechanisms. PMID:23513238

Lemogne, Cédric; Consoli, Silla M.; Geoffroy-Perez, Béatrice; Coeuret-Pellicer, Mireille; Nabi, Hermann; Melchior, Maria; Limosin, Frédéric; Zins, Marie; Ducimetière, Pierre; Goldberg, Marcel; Cordier, Sylvaine

2013-01-01

406

The associations between psychosocial working conditions and changes in common mental disorders: a follow-up study  

PubMed Central

Background Common mental disorders (CMD) are prevalent in working populations and have adverse consequences for employee well-being and work ability, even leading to early retirement. Several studies report associations between psychosocial working conditions and CMD. However, there is a lack of longitudinal research within a broad framework of psychosocial working conditions and improvement in CMD. The aim of this study was to examine the associations between several psychosocial working conditions and deteriorating and improving CMD among ageing employees over a five-to-six-year follow-up period. Methods The study is based on the Helsinki Health Study baseline survey in 2001–2002 and a follow-up in 2007 (N?=?4340, response rate 83%) conducted among 40-60-year-old female and male employees. The General Health Questionnaire (GHQ-12) was used to measure common mental disorders. Psychosocial working conditions were measured in terms of job strain, organisational justice, work-family interface, social support and workplace bullying. The covariates included sociodemographic and health factors. Results Following adjustment for all the covariates, family-to-work (OR 1.41, 95% Cl 1.04-1.91) and work-to-family conflicts (OR 1.99, 95% Cl 1.42-2.78) and workplace bullying (OR 1.40, 95% Cl 1.09-1.79) were associated with deterioration, and family-to-work conflicts (OR 1.65, 95% Cl 1.66-2.34) and social support (OR 1.47, 95% Cl 1.07-2.00) with improvement in CMD. Conclusions Adverse psychosocial working conditions contribute to poor mental health among employees. Preventing workplace bullying, promoting social support and achieving a better balance between work and family may help employees to maintain their mental health. PMID:24916716

2014-01-01

407

Persistence, clearance and reinfection regarding six high risk human papillomavirus types in Colombian women: a follow-up study  

PubMed Central

Background The design of new healthcare schemes which involve using molecular HPV screening means that both persistence and clearance data regarding the most prevalent types of HR-HPV occurring in cities in Colombia must be ascertained. Methods This study involved 219 HPV positive women in all of whom 6 types of HR-HPV had been molecularly identified and quantified; they were followed-up for 2 years. The Kaplan-Meier survival function was used for calculating the time taken for the clearance of each type of HPV. The role of a group of independent variables concerning the time taken until clearance was evaluated using a Cox proportional-hazards regression model or parametric (log-logistic) methods when necessary. Regarding viral load, the Wilcoxon rank-sum test was used for measuring the difference of medians for viral load for each type, according to the state of infection (cleared or persistent). The Kruskal-Wallis test was used for evaluating the change in the women’s colposcopy findings at the start of follow-up and at the end of it (whether due to clearance or the end of the follow-up period). Results It was found that HPV-18 and HPV-31 types had the lowest probability of becoming cleared (1.76 and 2.75 per 100 patients/month rate, respectively). Women from Colombian cities other than Bogotá had a greater probability of being cleared if they had HPV-16 (HR 2.58: 1.51–4.4 95% CI) or HPV-58 (1.79 time ratio: 1.33-2.39 95% CI) infection. Regarding viral load, HPV-45-infected women having 1?×?106 to 9.99?×?109 viral copies had better clearance compared to those having greater viral loads (1.61 time ratio: 1.01-2.57 95% CI). Lower HPV-31 viral load values were associated with this type’s persistence and changes in colposcopy findings for HPV-16 gave the worst prognosis in women having low absolute load values. Conclusions HPV infection clearance in this study was related to factors such as infection type, viral load and the characteristics of the cities from which the women came. Low viral load values would indicate viral persistence and a worse prognosis regarding a change in colposcopy findings. PMID:25030273

2014-01-01

408

Effect of exacerbations on quality of life in patients with chronic obstructive pulmonary disease: a 2 year follow up study  

PubMed Central

Background: A study was undertaken to evaluate exacerbations and their impact on the health related quality of life (HRQL) of patients with chronic obstructive pulmonary disease (COPD). Methods: A 2 year follow up study was performed in 336 patients with COPD of mean (SD) age 66 (8.2) years and mean (SD) forced expiratory volume in 1 second (FEV1) 33 (8)% predicted. Spirometric tests, questions regarding exacerbations of COPD, and HRQL measurements (St George's Respiratory Questionnaire (SGRQ) and SF-12 Health Survey) were conducted at 6 month intervals. Results: A total of 1015 exacerbations were recorded, and 103 (30.7%) patients required at least one hospital admission during the study. After adjustment for baseline characteristics and season of assessment, frequent exacerbations had a negative effect on HRQL in patients with moderate COPD (FEV1 35–50% predicted); the change in SGRQ total score of moderate patients with ?3 exacerbations was almost two points per year greater (worse) than those with <3 exacerbations during the follow up (p = 0.042). For patients with severe COPD (FEV1 <35% predicted) exacerbations had no effect on HRQL. The change in SGRQ total score of patients admitted to hospital was almost 2 points per year greater (worse) than patients not admitted, but this effect failed to show statistical significance in any severity group. There was a significant and independent seasonal effect on HRQL since SGRQ total scores were, on average, 3 points better in measurements performed in spring/summer than in those measured in the winter (p<0.001). Conclusions: Frequent exacerbations significantly impair HRQL of patients with moderate COPD. A significant and independent effect of seasonality was also observed. PMID:15115864

Miravitlles, M; Ferrer, M; Pont, A; Zalacain, R; Alvarez-Sala, J; Masa, F; Verea, H; Murio, C; Ros, F; Vidal, R

2004-01-01

409

The significance of molecular studies in the long-term follow-up of children with beckwith- wiedemann syndrome.  

PubMed

Beckwith-Wiedemann syndrome (BWS) is a congenital disorder of imprinting caused by epimutations and mutations affecting two imprinted loci on chromosome 11p15. Its clinical features are heterogeneous, including macrosomia, macroglossia, hemihyperplasia, abdominal wall defects, neonatal hypoglycemia, and increased risk of embryonal tumors such as Wilms tumor, adrenocortical carcinoma, hepatoblastoma, and neuroblastoma. The molecular and clinical heterogeneity of BWS makes the diagnosis challenging, but essential, since different etiologies of BWS have different clinical prognoses - most crucially, patients with gain of maternal methylation at imprinting control region type 1 (ICR1) are at significant risk of Wilms tumor or hepatoblastoma. We present three cases of BWS with different symptomatology and two different molecular diagnoses. The authors emphasize the importance of molecular studies in the long-term follow-up of children with BWS, including refinement of phenotype-genotype correlation and its connection with optimal management and tumor surveillance. PMID:24911853

Gizewska, Maria; Wilk, Malgorzata; Patalan, Michal; Mackay, Deborah; Peregud-Pegorzelski, Jaroslow; Gawrych, Elzbieta; Walczak, Mieczyslaw; Petriczko, Elzbieta; Brodkiewicz, Andrzej

2014-01-01

410

A Spiderless Arachnophobia Therapy: Comparison between Placebo and Treatment Groups and Six-Month Follow-Up Study  

PubMed Central

We describe a new arachnophobia therapy that is specially suited for those individuals with severe arachnophobia who are reluctant to undergo direct or even virtual exposure treatments. In this therapy, patients attend a computer presentation of images that, while not being spiders, have a subset of the characteristics of spiders. The Atomium of Brussels is an example of such an image. The treatment group (n = 13) exhibited a significant improvement (time × group interaction: P = .0026) when compared to the placebo group (n = 12) in a repeated measures multivariate ANOVA. A k-means clustering algorithm revealed that, after 4 weeks of treatment, 42% of the patients moved from the arachnophobic to the nonarachnophobic cluster. Six months after concluding the treatment, a follow-up study showed a substantial consolidation of the recovery process where 92% of the arachnophobic patients moved to the nonarachnophobic cluster. PMID:17713595

Granado, Laura Carmilo; Ranvaud, Ronald; Peláez, Javier Ropero

2007-01-01

411

Mesomelic dysplasia with acral synostoses Verloes-David-Pfeiffer type: follow-up study documents progressive clinical course.  

PubMed

Verloes-David-Pfeiffer mesomelia-synostoses syndrome is an autosomal-dominant form of mesomelic dysplasia comprising typical acral synostoses combined with ptosis, hypertelorism, palatal abnormality, CHD, and ureteral anomalies. Since the original reports in 1995, two other patients have been described with this syndrome, one of them the patient reported in 1998 by Day-Salvatore. In this article, we report on the follow-up of some of the original cases and review the literature. We confirm that the Verloes-David-Pfeiffer syndrome (VDPS) is a progressive skeletal disorder that despite repeated corrective surgical intervention leads to severe limb deformities. No mutations were detected in the FLNB gene. To date, the cause and the pathogenesis of VDPS remain unknown. The latter is characterized in this study as a syndromic type of skeletal dysplasia because besides congenital malformations and multiple acromelic synostoses arising prenatally, VDPS manifests in postnatal life as a severe osteochondrodysplasia. PMID:19725128

Isidor, Bertrand; Hamel, Antoine; Plasschaert, Frank; Claus, Lieve; Mercier, Jacques-Marie; Mortier, Geert R; Leroy, Jules G; Verloes, Alain; David, Albert

2009-10-01

412

Associations of Physical Activity and Sedentary Behavior with Academic Skills – A Follow-Up Study among Primary School Children  

PubMed Central

Background There are no prospective studies that would have compared the relationships of different types of physical activity (PA) and sedentary behavior (SB) with academic skills among children. We therefore investigated the associations of different types of PA and SB with reading and arithmetic skills in a follow-up study among children. Methods The participants were 186 children (107 boys, 79 girls, 6–8 yr) who were followed-up in Grades 1–3. PA and SB were assessed using a questionnaire in Grade 1. Reading fluency, reading comprehension and arithmetic skills were assessed using standardized tests at the end of Grades 1–3. Results Among all children more recess PA and more time spent in SB related to academic skills were associated with a better reading fluency across Grades 1–3. In boys, higher levels of total PA, physically active school transportation and more time spent in SB related to academic skills were associated with a better reading fluency across the Grades 1–3. Among girls, higher levels of total PA were related to worse arithmetic skills across Grades 1–3. Moreover, total PA was directly associated with reading fluency and arithmetic skills in Grades 1–3 among girls whose parents had a university degree, whereas these relationships were inverse in girls of less educated parents. Conclusions Total PA, physically active school transportation and SB related to academic skills may be beneficial for the development of reading skills in boys, whereas factors that are independent of PA or SB may be more important for academic skills in girls. Trial Registration ClinicalTrials.gov: NCT01803776 PMID:25207813

Haapala, Eero A.; Poikkeus, Anna-Maija; Kukkonen-Harjula, Katriina; Tompuri, Tuomo; Lintu, Niina; Väistö, Juuso; Leppänen, Paavo H. T.; Laaksonen, David E.; Lindi, Virpi; Lakka, Timo A.

2014-01-01

413

Long-term follow-up of study participants from prophylactic HIV vaccine clinical trials in Africa  

PubMed Central

Long-term safety is critical for the development and later use of a vaccine to prevent HIV/AIDS. Likewise, the persistence of vaccine-induced antibodies and their impact on HIV testing must be established. IAVI has sponsored several Phase I and IIA HIV vaccine trials enrolling healthy, HIV-seronegative African volunteers. Plasmid DNA and viral vector based vaccines were tested. No vaccine-related serious adverse events were reported. After completion of vaccine trials conducted between 2001–2007, both vaccine and placebo recipients were offered enrolment into an observational long-term follow-up study (LTFU) to monitor potential late health effects and persistence of immune responses. At scheduled 6-monthly clinic visits, a health questionnaire was administered; clinical events were recorded and graded for severity. Blood was drawn for HIV testing and cellular immune assays. 287 volunteers were enrolled; total follow-up after last vaccination was 1463 person years (median: 5.2 years). Ninety-three (93)% of volunteers reported good health at their last LTFU visit. Infectious diseases and injuries accounted for almost 50% of the 175 reported clinical events, of which over 95% were mild or moderate in severity. There were 30 six pregnancies, six incident HIV infections and 14 volunteers reported cases of social harm. Persistence of immune responses was rare. No safety signal was identified. No potentially vaccine-related medical condition, no immune mediated disease, or malignancy was reported. HIV vaccines studied in these trials had a low potential of induction of persisting HIV antibodies. PMID:24374365

Schmidt, Claudia; Jaoko, Walter; Omosa-Manyonyi, Gloria; Kaleebu, Pontiano; Mpendo, Juliet; Nanvubya, Annet; Karita, Etienne; Bayingana, Roger; Bekker, Linda-Gail; Chomba, Elwyn; Kilembe, William; Nchabeleng, Maphoshane; Nyombayire, Julien; Stevens, Gwynn; Chetty, Paramesh; Lehrman, Jennifer; Cox, Josephine; Allen, Susan; Dally, Len; Smith, Carol; Fast, Patricia E

2014-01-01

414

Long-term follow-up of study participants from prophylactic HIV vaccine clinical trials in Africa.  

PubMed

Long-term safety is critical for the development and later use of a vaccine to prevent HIV/AIDS. Likewise, the persistence of vaccine-induced antibodies and their impact on HIV testing must be established. IAVI has sponsored several Phase I and IIA HIV vaccine trials enrolling healthy, HIV-seronegative African volunteers. Plasmid DNA and viral vector based vaccines were tested. No vaccine-related serious adverse events were reported. After completion of vaccine trials conducted between 2001-2007, both vaccine and placebo recipients were offered enrolment into an observational long-term follow-up study (LTFU) to monitor potential late health effects and persistence of immune responses. At scheduled 6-monthly clinic visits, a health questionnaire was administered; clinical events were recorded and graded for severity. Blood was drawn for HIV testing and cellular immune assays. 287 volunteers were enrolled; total follow-up after last vaccination was 1463 person years (median: 5.2 years). Ninety-three (93)% of volunteers reported good health at their last LTFU visit. Infectious diseases and injuries accounted for almost 50% of the 175 reported clinical events, of which over 95% were mild or moderate in severity. There were 30 six pregnancies, six incident HIV infections and 14 volunteers reported cases of social harm. Persistence of immune responses was rare. No safety signal was identified. No potentially vaccine-related medical condition, no immune mediated disease, or malignancy was reported. HIV vaccines studied in these trials had a low potential of induction of persisting HIV antibodies. PMID:24374365

Schmidt, Claudia; Jaoko, Walter; Omosa-Manyonyi, Gloria; Kaleebu, Pontiano; Mpendo, Juliet; Nanvubya, Annet; Karita, Etienne; Bayingana, Roger; Bekker, Linda-Gail; Chomba, Elwyn; Kilembe, William; Nchabeleng, Maphoshane; Nyombayire, Julien; Stevens, Gwynn; Chetty, Paramesh; Lehrman, Jennifer; Cox, Josephine; Allen, Susan; Dally, Len; Smith, Carol; Fast, Patricia E

2014-01-01

415

U.S.-MEXICO BORDER PROGRAM ARIZONA BORDER STUDY--STANDARD OPERATING PROCEDURE FOR CODING: FOOD DIARY FOLLOW UP (UA-D-10.0)  

EPA Science Inventory

The purpose of this SOP is to define the coding strategy for the Food Diary Follow Up Questionnaire. This questionnaire was developed for use in the Arizona NHEXAS project and the Border study. Keywords: data; coding; food diary follow up questionnaire. The U.S.-Mexico Border ...

416

The National Longitudinal Study of the High School Class of 1972 (NLS-72), Fifth Follow-Up (1986) Data File [machine-readable data file].  

ERIC Educational Resources Information Center

This machine-readable data file (MDRF) contains information from the fifth follow-up survey of the National Longitudinal Survey of the High School Class of 1972. The survey was carried out along with the third survey of the High School and Beyond Study. The fifth follow-up data file consists of 12,841 records. The data tape contains information on…

National Center for Education Statistics (ED), Washington, DC.

417

Clinical, HLA, and roentgenological follow up study of patients with juvenile arthritis: comparison between the long term outcome of transient and persistent arthritis in children  

Microsoft Academic Search

Fifty two patients with juvenile chronic arthritis (JCA) and 22 patients with arthritis of short duration (transient arthritis, TA) were studied in a follow up investigation. Nineteen (37%) of the patients with JCA had peripheral arthritis or sequelae in the form of contractures at follow up, and in addition one patient was treated with corticosteroids. In contrast, only one (5%)

H Ström; N Lindvall; B Hellström; L Rosenthal

1989-01-01

418

NHEXAS PHASE I ARIZONA STUDY--STANDARD OPERATING PROCEDURE FOR CODING: FOOD DIARY FOLLOW UP (UA-D-10.0)  

EPA Science Inventory

The purpose of this SOP is to define the coding strategy for the Food Diary Follow Up Questionnaire. This questionnaire was developed for use in the Arizona NHEXAS project and the "Border" study. Keywords: data; coding; food diary follow up questionnaire. The National Human Ex...

419

Prospective study of the cementless "New Wave" total knee mobile-bearing arthroplasty: 8-year follow-up.  

PubMed

One of the main factors affecting the survival of a total knee arthroplasty (TKA) is the fixation method. The constraints placed on the bone-implant interface of a mobile-bearing TKA must be taken in account during the design and evaluation phases. For more than two decades, calcium phosphate ceramics, particularly hydroxyapatitis, have been used in Europe to accelerate the bone integration of cementless implants. A prospective study of patients continuously recruited by three senior surgeons at three French private hospitals has been carried out. There were no exclusion criteria. Eighty-four (84) cementless mobile-bearing total knee prosthesis of the brand "New Wave" were implanted in 74 patients over a 2-year period (2004-2005). Implant survival at 8 years was 95% [with a confidence interval of 95%: 80.2-96.4%] when revision for any cause was defined as the endpoint. Five implants required surgical revision to exchange all or part of the implant: two for aseptic loosening of tibial component, one for osteolysis, one for persistent flessum (30°) and one for tibial periprosthetic fracture. Completely integrated implants and event-free outcomes were recorded in 91.4% of the cases at eight-year follow-up. The Hospital for Special Surgery score significantly improved from 56.8/100 points before the surgery to 83.9/100 points at the last follow-up (p < 0.05). Radiologically, only one patient had radiolucent lines around the tibial and femoral components. This cementless total knee prosthesis yielded good medium-term survival. Cementless arthroplasty can generate solid and durable bone fixation in this total weight-bearing implant, and it seems that the hidroxyapathitis surface in this series stimulate the bone integration at the bone-implant interface. PMID:24858380

Normand, Xavier; Pinçon, Jean-Louis; Ragot, Jean-Marie; Verdier, Régis; Aslanian, Thierry

2015-02-01

420

Serial Changes in Sexual Function Following Holmium Laser Enucleation of the Prostate: A Short-term Follow-up Study  

PubMed Central

Purpose To evaluate the serial changes in sexual function in the short-term period after holmium laser enucleation of the prostate (HoLEP) for benign prostatic hyperplasia (BPH) and to investigate whether a change in each domain of the International Index of Erectile Function (IIEF) is associated with improvement of micturition. Materials and Methods Thirty-eight potent men who underwent HoLEP and in whom complete 12-month follow-up data on the IIEF were available were included in this retrospective study. All patients underwent a baseline evaluation for BPH. The surgical outcome was evaluated at 1, 3, 6, and 12 months postoperatively by use of the International Prostate Symptom Score, IIEF, and uroflowmetry. Results The mean age and body mass index of the patients was 64.5±6.2 years and 24.2±2.6 kg/m2, respectively. Mean total prostate volume and transitional zone volume were 48.8±18.8 ml and 24.2±16.1 ml, respectively. Most IIEF domain scores showed a slight decrease at 1, 3, and 6 months after surgery but recovered to the baseline or showed a marginal but nonsignificant increase at 12 months postoperatively compared with baseline. Orgasmic function and the overall sexual satisfaction domain score remained slightly reduced up to 12 months postoperatively. There was no significant correlation between improvement of micturition and change in sexual function throughout the follow-up period after surgery. Conclusions Although HoLEP achieves significant improvements in micturition, overall sexual function decreases slightly in the early postoperative period, but recovers to the baseline at 12 months postoperatively. Our data suggest that changes in sexual function after HoLEP are not associated with improvement of micturition. PMID:22379589

Jeong, Min Su; Ha, Seung Beom; Lee, Chang Ju; Cho, Min Chul; Kim, Soo Woong

2012-01-01

421

A longitudinal study on the osteoarthritic change of the temporomandibular joint based on 1-year follow-up computed tomography.  

PubMed

This study aims to report the results of a 1-year computed tomographic (CT) follow up of 54 temporomandibular joints (TMJs) affected by osteoarthritis (OA) and to provide longitudinal information on changes in OA and its relationship with clinical signs and symptoms. TMJ OA was diagnosed by history, clinical and CT examinations. The second CT examination was done after about 1 year of conservative treatment. Joints were divided into three groups labeled as no change, improved CT, and worsened CT groups depending on the longitudinal bony change of OA observed in the CT. The sex distribution, mean age, joint noise, subjective pain, joint tenderness, masticatory muscle tenderness, and improvement of subjective symptoms were not different between the groups at the first and second examination, while maximum (p < 0.01) and painless mouth opening range (p < 0.001) at the first examination were both smaller in the worsened CT group. Although the clinical signs and symptoms of OA were improved in 40 joints, 74.1%, at 7.2 ± 4.6 months, the amount if improvement did not differ between the groups. The extent of the destructive change of the condyle was highest in the improved CT group at the first (p < 0.001) and in the worsened CT group at the second examination (p < 0.001). These results imply that the prognosis of OA changes may be independent of the clinical signs and symptoms. More specific longitudinal information as regards OA changes of the TMJ based on a larger sample and a longer follow-up period would be likely to provide a better understanding of TMJ OA. PMID:22075324

Lee, Jeong-Yun; Kim, Dae-Jung; Lee, Sang-Goo; Chung, Jin-Woo

2012-12-01

422

Basal low antioxidant capacity correlates with cognitive deficits in early onset psychosis. A 2-year follow-up study.  

PubMed

The objective of the study is to examine the association of baseline total antioxidant status (TAS) and glutathione (GSH) levels with short- and long-term cognitive functioning in patients with early onset first-episode psychosis, comparing affective and non-affective psychoses. We analysed 105 patients with an early onset-first episode psychosis (age 9-17 years) and 97 healthy controls. Blood samples were taken at admission for measurement of TAS and GSH, and cognitive performance was assessed at baseline and at 2years of follow-up. Regression analysis was used to assess the relationship between TAS/GSH levels at baseline and cognitive performance at both time points, controlling for confounders. Baseline TAS and GSH levels were significantly lower in patients than healthy controls. In patients, baseline TAS was positively associated with the global cognition score at baseline (p=0.048) and two years later (p=0.005), while TAS was not associated with cognitive functioning in healthy controls. Further, baseline TAS in patients was specifically associated with the memory domain at baseline and with the memory and attention domains two years later. Stratifying by affective and non-affective psychoses, significant associations were only found between TAS and cognition in the non-affective psychosis group. Baseline GSH levels were not associated with cognitive functioning at either time point in either group. The antioxidant defence capacity in early onset first-episode psychotic patients is directly correlated with global cognition at baseline and at 2years of follow-up, especially in non-affective psychosis. PMID:24768133

Martínez-Cengotitabengoa, Mónica; Micó, Juan Antonio; Arango, Celso; Castro-Fornieles, Josefina; Graell, Montserrat; Payá, Beatriz; Leza, Juan Carlos; Zorrilla, Iñaki; Parellada, Mara; López, M Purificación; Baeza, Inmaculada; Moreno, Carmen; Rapado-Castro, Marta; González-Pinto, Ana

2014-06-01

423

Photoselective vaporization of prostate vs. transurethral resection of prostate: A prospective, randomized study with one year follow-up  

PubMed Central

Objectives: To evaluate in a prospective, randomized study, the efficacy and safety profile of photoselective vaporization of prostate (PVP) using a 80W potassium titanyl phosphate (KTP) laser when compared to standard transurethral resection of prostate (TURP) in patients with lower urinary tract symptoms (LUTS) due to benign prostatic enlargement (BPE). Materials and Methods: Between February 2009 and August 2009, 117 patients satisfying the eligibility criteria underwent surgery [60 PVP{Group A}; 57 TURP{Group B}]. The groups were compared for functional outcome (both subjective and objective parameters), perioperative parameters and complications, with a follow up of one year. P value<0.05 was considered statistically significant. Results: The baseline characteristics of the two groups were comparable. Mean age was 66.68 years and 65.74 years, mean IPSS score was 19.98 and 20.88, mean prostate volume was 44.77 cc and 49.02 cc in Group A and B, respectively. Improvements in IPSS, QOL, prostate volume, Q max and PVRU at 12 months were similar in both groups. PVP patients had longer operating time, lesser perioperative blood loss, shorter catheterization time and a higher dysuria rate when compared to TURP patients. The overall complication rate was similar in the two groups. Conclusions: In patients with LUTS due to BPE, KTP-PVP is an equally efficacious alternative to TURP with durable results at one year follow up with additional benefits of lesser perioperative blood loss, lesser transfusion requirements and a shorter catheterization time. Long term comparative data is awaited to clearly define the role of KTP-PVP in such patients. PMID:23204660

Mohanty, Nayan K.; Vasudeva, Pawan; Kumar, Anup; Prakash, Sanjay; Jain, Manoj; Arora, Rajender P.

2012-01-01

424

Four-year follow-up study in a NF1 Boy with a focal pontine hamartoma  

PubMed Central

Neurofibromatosis is a collective name for a group of genetic conditions in which benign tumours affect the nervous system. Type 1 is caused by a genetic mutation in the NF1 gene (OMIM 613113) and symptoms can vary dramatically between individuals, even within the same family. Some people have very mild skin changes, whereas others suffer severe medical complications. The condition usually appears in childhood and is diagnosed if two of the following are present: six or more café-au-lait patches larger than 1.5 cm in diameter, axillary or groin freckling, 2 or more Lisch nodules (small pigmented areas in the iris of the eye), 2 or more neurofibromas, optic pathway gliomas, bone dysplasia, and a first-degree family relative with Neurofibromatosis type 1. The pattern of inheritance is autosomal dominant, however, half of all NF1 cases are ‘sporadic’ and there is no family history. Neurofibromatosis type 1 is an extremely variable condition whose morbidity and mortality is largely dictated by the occurrence of the many complications that may involve any of the body systems. We describe a family affected by NF1 in whom genetic molecular analysis identified the same mutation in the son and father. Routine MRI showed pontine focal lesions in the eight-year-old son, though not in the father. We performed a four years follow-up study and at follow-up pontine hamartoma size remained unchanged in the son, and the father showed still no brain lesions, confirming thus an intra-familial phenotype variability. PMID:23399325

2013-01-01

425

TEN YEAR REVIEW OF PLASTICS RECYCLING  

EPA Science Inventory

A short history of the practice of plastics recycling as practiced in the United States and Europe for the past ten years indicates that much progress has been made in educating the public sector about the environmental damage done by indiscriminating disposal of plastic items. e...

426

Preparing Future Faculty: Ten Years Later  

ERIC Educational Resources Information Center

When Sean Murphy designed the Graduate Student Internship Program at the College of Lake County (CLC), his 2001 TETYC article about the then two-year-old program detailed his programmatic response to the job market. Ten years later, the CLC-DePaul University partnership remains the strongest of the original dozen cross-sector relationships CLC…

Murphy, Sean P.; Aiossa, Elizabeth; Winter, Mary Mugica

2010-01-01

427

Central nervous system involvement in Whipple disease: clinical study of 18 patients and long-term follow-up.  

PubMed

Whipple disease (WD) is a rare multisystemic infection with a protean clinical presentation. The central nervous system (CNS) is involved in 3 situations: CNS involvement in classic WD, CNS relapse in previously treated WD, and isolated CNS infection. We retrospectively analyzed clinical features, diagnostic workup, brain imaging, cerebrospinal fluid (CSF) study, treatment, and follow-up data in 18 patients with WD and CNS infection. Ten men and 8 women were included with a median age at diagnosis of 47 years (range, 30-56 yr). The median follow-up duration was 6 years (range, 1-19 yr). As categorized in the 3 subgroups, 11 patients had classic WD with CNS involvement, 4 had an isolated CNS infection, and 3 had a neurologic relapse of previously treated WD. CNS involvement occurred during prolonged trimethoprim-sulfamethoxazole (TMP-SMX) treatment in 1 patient with classic WD. The neurologic symptoms were various and always intermingled, as follows: confusion or coma (17%) related to meningo-encephalitis or status epilepticus; delirium (17%); cognitive impairment (61%) including memory loss and attention defects or typical frontal lobe syndrome; hypersomnia (17%); abnormal movements (myoclonus, choreiform movements, oculomasticatory myorhythmia) (39%); cerebellar ataxia (11%); upper motor neuron (44%) or extrapyramidal symptoms (33%); and ophthalmoplegia (17%) in conjunction or not with progressive supranuclear palsy. No specific pattern was correlated with any subgroup. Brain magnetic resonance imaging (MRI) revealed a unique focal lesion (35%), mostly as a tumorlike brain lesion, or multifocal lesions (23%) involving the medial temporal lobe, midbrain, hypothalamus, and thalamus. Periventricular diffuse leukopathy (6%), diffuse cortical atrophy (18%), and pachymeningitis (12%) were observed. The spinal cord was involved in 2 cases. MRI showed ischemic sequelae at diagnosis or during follow-up in 4 patients. Brain MRI was normal despite neurologic symptoms in 3 cases. CSF cytology was normal in 62% of patients, whereas Tropheryma whipplei polymerase chain reaction (PCR) analysis was positive in 92% of cases with tested CSF. Periodic acid-Schiff (PAS)-positive cells were identified in cerebral biopsies of 4 patients. All patients were treated with antimicrobial therapy for a mean duration of 2 years (range, 1-7 yr) with either oral monotherapy (TMP-SMX, doxycycline, third-generation cephalosporins) or a combination of antibiotics that sometimes followed parenteral treatment with beta-lactams and aminoglycosides. Eight patients also received hydroxychloroquine. At the end of follow-up, the clinical outcome was favorable in 14 patients (78%), with mild to moderate sequelae in 9. Thirteen patients (72%) had stopped treatment for an average time of 4 years (range, 0.7-14 yr). Four patients had clinical worsening despite antimicrobial therapy; 2 of those died following diffuse encephalitis (n = 1) and lung infection (n = 1). In conclusion, the neurologic manifestations of WD are diverse and may mimic almost any neurologic condition. Brain involvement may occur during or after TMP-SMX treatment. CSF T. whipplei PCR analysis is a major tool for diagnosis and may be positive in the absence of meningitis. Immune reconstitution syndrome may occur in the early months of treatment. Late prognosis may be better than previously reported, as a consequence of earlier diagnosis and a better use of antimicrobial therapy, including hydroxychloroquine and doxycycline combination. PMID:24145700

Compain, Caroline; Sacre, Karim; Puéchal, Xavier; Klein, Isabelle; Vital-Durand, Denis; Houeto, Jean-Luc; De Broucker, Thomas; Raoult, Didier; Papo, Thomas

2013-11-01

428

Ten-year results of the Press Fit Condylar Sigma total knee replacement.  

PubMed

We report ten-year clinical and radiological follow-up data for the Sigma Press Fit Condylar total knee replacement system (Sigma PFC TKR). Between October 1998 and October 1999 a total of 235 consecutive PFC Sigma TKRs were carried out in 203 patients. Patients were seen at a specialist nurse-led clinic seven to ten days before admission and at six and 18 months, three, five and eight to ten years after surgery. Data were recorded prospectively at each clinic visit. Radiographs were obtained at the five- and eight- to ten-year follow-up appointments. Of the 203 patients, 147 (171 knees) were alive at ten years and 12 were lost to follow-up. A total of eight knees (3.4%) were revised, five for infection and three to change the polyethylene insert. The survival at ten years with an endpoint of revision for any reason was 95.9%, and with an endpoint of revision for aseptic failure was 98.7%. The mean American Knee Society Score (AKSS) was 79 (10 to 99) at eight to ten years, compared with 31 (2 to 62) pre-operatively. Of 109 knee with radiographs reviewed, 47 knees had radiolucent lines but none showed evidence of loosening. PMID:23365025

Arthur, C H C; Wood, A M; Keenan, A C M; Clayton, R A E; Walmsley, P; Brenkel, I

2013-02-01

429

Ten Years of Experience with the GORE EXCLUDER{sup Registered-Sign} Stent-Graft for the Treatment of Aortic and Iliac Aneurysms: Outcomes from a Single Center Study  

SciTech Connect

Purpose: This study was designed to assess the long-term outcome of selected patients with aortic, aortoiliac, and isolated common iliac aneurysms treated with the GORE EXCLUDER{sup Registered-Sign} stent-graft. Methods: Between December 1998 and June 2010, 121 nonconsecutive patients underwent insertion of a GORE EXCLUDER{sup Registered-Sign} stent-graft to treat an aortic (n = 80; 66%), aortoiliac (n = 25; 21%), or isolated common iliac (n = 16; 13%) aneurysm. Procedural and follow-up data were collected prospectively. Primary endpoints are overall survival, intervention-free survival, and freedom from aneurysm rupture. Secondary endpoints are device- and procedure-related complications, including all types of endoleaks or endotension, and reintervention. Results: The mean follow-up is 4.98 years (standard deviation, 3.18; median follow-up, 4.05 years). The estimated percentage overall survival (with 95% confidence interval) after respectively 5 and 10 years of follow-up is 74.5% (65.8; 81.3) and 57.8% (47.7; 66.7). The estimated intervention-free survival after respectively 5 and 10 years is 90% (84.3; 96.1) and 77.7% (67; 88.4). There was no aneurysm rupture during follow-up. Early postoperative complications occurred in 16 patients (13%); none were fatal. Late reinterventions were performed in 18 patients (15%). Finally, throughout the follow-up period, endoleaks were identified: type I (n = 4; 3%); type II (n = 39; 32%); type III (n = 0; 0%); endotension was seen in 11 patients (9%). Conclusions: Aneurysm exclusion with use of the GORE EXCLUDER{sup Registered-Sign} stent-graft is durable through a mean follow-up of nearly 5 years. There was no postprocedural aneurysm rupture. Complications occurred throughout the follow-up period, requiring continued clinical and radiological surveillance.

Maleux, G., E-mail: geert.maleux@uzleuven.be; Claes, H.; Van Holsbeeck, A. [University Hospitals Leuven, Department of Radiology (Belgium); Janssen, R. [University Hospitals Leuven, Department of Vascular Surgery (Belgium); Laenen, A. [Catholic University of Leuven, Department of Biostatistics and Statistical Bioinformatics (Belgium); Heye, S. [University Hospitals Leuven, Department of Radiology (Belgium); Houthoofd, S.; Fourneau, I. [University Hospitals Leuven, Department of Vascular Surgery (Belgium)

2012-06-15

430

A 4-Year Follow-up Cohort Study of the Respiratory Functions in Toner-handling Workers  

PubMed Central

Background Focusing on the respiratory function for health effect indices, we conducted a cross-sectional study on workers who did and did not handle toner to compare the longitudinal changes. Methods Among 116 individuals who worked for a Japanese business equipment manufacturer and participated in the study, the analysis included 69 male workers who we were able to follow up for 4 years. We categorized the 40 workers engaged in toner-handling work as the exposed group and the 29 workers not engaged in these tasks as the referent group, and compared their respiratory function test results: peak expiratory flow rate (PEFR), vital capacity (VC), predicted vital capacity (%VC), forced expiratory volume in 1 second (FEV1), and forced expiratory volume in 1 second as a percent of forced vital capacity (FEV1%). Results The cross-sectional study of the respiratory function test results at the baseline and at the 5th year showed no statistically significant differences in PEFR, VC, %VC, FEV1, and FEV1% between the exposed and referent workers. Also, respiratory function time-course for 4 years was calculated and compared between the groups. No statistically significant differences were shown. Conclusion Our study does not suggest any toner exposure effects on respiratory function. However, the number of subjects was small in our study; studies of larger populations will be desired in the future. PMID:25516816

Yanagi, Nobuaki; Kitamura, Hiroko; Mizuno, Mitsuhito; Hata, Koichi; Uchiyama, Tetsuro; Kuga, Hiroaki; Matsushita, Tetsuhiro; Kurosaki, Shizuka; Uehara, Masamichi; Ogami, Akira; Higashi, Toshiaki

2014-01-01

431

Following-up in strategic environmental assessment: a case study of 20-year forest management planning in Saskatchewan, Canada  

Microsoft Academic Search

The concept of strategic environmental assessment (SEA) has received considerable attention in recent years; however, the focus has been on the pre-decision stages of policies, plans and programs with much less attention to post-decision follow-up and monitoring. In those instances where SEA follow-up has been addressed, it has been done so much more from a conceptual than a practical perspective.

Maia Gachechiladze; Bram F. Noble; Brent W. Bitter

2009-01-01

432

Physical and mental development of children after levonorgestrel emergency contraception exposure: a follow-up prospective cohort study.  

PubMed

Levonorgestrel (LNG), a dedicated emergency contraception (EC) product, has been available over-the-counter in China for more than 14 yr. Although LNG-EC is considered to have no effects on the developing fetus if the contraceptive fails and pregnancy occurs, there have been a few studies specifically examining this issue. The purpose of this study was to compare the physical and mental development of children born after LNG-EC failure with that of a cohort of children born to mothers with no history of exposure to LNG or any teratogenic substances. A group of 195 children who were exposed to LNG-EC during their mothers' conception cycle (study group) were matched to a group of 214 children without exposure to LNG (control group). The physical and mental development of the children were evaluated and compared over a 2-yr period. There were four congenital malformations in the study group and three in the control group (2.1% vs. 1.4%, respectively, P > 0.05). Over the 2-yr follow-up period, there were no statistically significant differences between the two groups with respect to children's weight, height, head circumference, and intelligence scores, and the values of all parameters of both groups were similar to those of the national standards. In summary, LNG-EC has no effect on the physical growth, mental development, or occurrence of birth defects in children born from pregnancies in which EC failed. PMID:24899575

Zhang, Lin; Ye, Weiping; Yu, Wen; Cheng, Linan; Shen, Lixiao; Yang, Zujing

2014-07-01

433

Mortality among young injection drug users in San Francisco: a 10-year follow-up of the UFO study.  

PubMed

This study examined associations between mortality and demographic and risk characteristics among young injection drug users in San Francisco, California, and compared the mortality rate with that of the population. A total of 644 young (<30 years) injection drug users completed a baseline interview and were enrolled in a prospective cohort study, known as the UFO ("U Find Out") Study, from November 1997 to December 2007. Using the National Death Index, the authors identified 38 deaths over 4,167 person-years of follow-up, yielding a mortality rate of 9.1 (95% confidence interval: 6.6, 12.5) per 1,000 person-years. This mortality rate was 10 times that of the general population. The leading causes of death were overdose (57.9%), self-inflicted injury (13.2%), trauma/accidents (10.5%), and injection drug user-related medical conditions (13.1%). Mortality incidence was significantly higher among those who reported injecting heroin most days in the past month (adjusted hazard ratio = 5.8, 95% confidence interval: 1.4, 24.3). The leading cause of death in this group was overdose, and primary use of heroin was the only significant risk factor for death observed in the study. These findings highlight the continued need for public health interventions that address the risk of overdose in this population in order to reduce premature deaths. PMID:22227793

Evans, Jennifer L; Tsui, Judith I; Hahn, Judith A; Davidson, Peter J; Lum, Paula J; Page, Kimberly

2012-02-15

434

A follow-up study on the physique, body composition, physical fitness, and isokinetic strength of female collegiate Taekwondo athletes.  

PubMed

The purpose of the study was to analyze changes in physique, body composition, physical fitness, and isokinetic strength in female collegiate taekwondo athletes. The study included 14 subjects, of whom 8 were followed up throughout the study. Anthropometric characteristics included body weight, height, sitting height, circumferences, and bone width. Physical fitness parameters included flexibility, agility, muscle strength, muscular endurance, power, speed, and cardiorespiratory endurance. Peak torque, mean power, and H/Q ratio were analyzed by using Cybex 770. All data were analyzed by using the SAS statistical program. Paired t test was performed, with 0.05 as the significance level. The results indicated significant changes in body weight, and upper arm and flexed upper arm circumferences during the experimental period. Test scores for plate tapping, and sit and reach significantly increased, but that for power decreased. In addition, the peak power of right flexion at 180°/sec was significantly increased, as well as the mean power of right and left flexion, and the H/Q ratio at 180°/sec. PMID:25830145

Kim, Hyun-Bae; Jung, Hyun-Chul; Song, Jong-Kook; Chai, Joo-Hee; Lee, Eun-Jae

2015-02-01

435

When Do Natural Language Metaphors Influence Reasoning? A Follow-Up Study to Thibodeau and Boroditsky (2013)  

PubMed Central

In this article, we offer a critical view of Thibodeau and Boroditsky who report an effect of metaphorical framing on readers' preference for political measures after exposure to a short text on the increase of crime in a fictitious town: when crime was metaphorically presented as a beast, readers became more enforcement-oriented than when crime was metaphorically framed as a virus. We argue that the design of the study has left room for alternative explanations. We report four experiments comprising a follow-up study, remedying several shortcomings in the original design while collecting more encompassing sets of data. Our experiments include three additions to the original studies: (1) a non-metaphorical control condition, which is contrasted to the two metaphorical framing conditions used by Thibodeau and Boroditsky, (2) text versions that do not have the other, potentially supporting metaphors of the original stimulus texts, (3) a pre-exposure measure of political preference (Experiments 1–2). We do not find a metaphorical framing effect but instead show that there is another process at play across the board which presumably has to do with simple exposure to textual information. Reading about crime increases people's preference for enforcement irrespective of metaphorical frame or metaphorical support of the frame. These findings suggest the existence of boundary conditions under which metaphors can have differential effects on reasoning. Thus, our four experiments provide converging evidence raising questions about when metaphors do and do not influence reasoning. PMID:25490704

Steen, Gerard J.; Reijnierse, W. Gudrun; Burgers, Christian

2014-01-01

436

A follow-up study on the physique, body composition, physical fitness, and isokinetic strength of female collegiate Taekwondo athletes  

PubMed Central

The purpose of the study was to analyze changes in physique, body composition, physical fitness, and isokinetic strength in female collegiate taekwondo athletes. The study included 14 subjects, of whom 8 were followed up throughout the study. Anthropometric characteristics included body weight, height, sitting height, circumferences, and bone width. Physical fitness parameters included flexibility, agility, muscle strength, muscular endurance, power, speed, and cardiorespiratory endurance. Peak torque, mean power, and H/Q ratio were analyzed by using Cybex 770. All data were analyzed by using the SAS statistical program. Paired t test was performed, with 0.05 as the significance level. The results indicated significant changes in body weight, and upper arm and flexed upper arm circumferences during the experimental period. Test scores for plate tapping, and sit and reach significantly increased, but that for power decreased. In addition, the peak power of right flexion at 180°/sec was significantly increased, as well as the mean power of right and left flexion, and the H/Q ratio at 180°/sec.

Kim, Hyun-Bae; Jung, Hyun-Chul; Song, Jong-Kook; Chai, Joo-Hee; Lee, Eun-Jae

2015-01-01

437

Childhood correlates of adult TV viewing time: a 32-year follow-up of the 1970 British Cohort Study  

PubMed Central

Background To identify, using a longitudinal data set, parental and childhood correlates of adult television (TV) viewing time at 32-year follow-up. Method Data were derived from the 1970 British Cohort Study, a longitudinal observational study of 17?248 British people born in a single week of 1970. The present analyses incorporated data from the age 10 and 42-year surveys. When participants were aged 10?years, their mothers provided information on how often participants watched TV and played sports (never/sometimes/often), and parents’ own occupation, as well as height and weight. A health visitor objectively assessed participants’ height and weight at age 10. Thirty-two years later, when participants were aged 42?years, they reported their daily TV viewing hours (none/0?1/1<3/3<5/?5), physical activity and health status. Associations between putative childhood and parental correlates and adult TV viewing time were investigated using logistic regression. Results Valid data at both time points were available for 6188 participants. Logistic regression models showed that those who reported ‘often’ watching TV at baseline were significantly more likely to watch >3?h/days of TV at follow-up (OR 1.42, 95% CI 1.21 to 1.65), as were those whose father was from a lower socio-occupational class (intermediate, routine/manual) compared with managerial (OR 1.55, 95% CI 1.14 to 2.11; OR 2.05, 95% CI 1.47 to 2.87). Body mass index (BMI) at age 10 was inversely associated with high TV in adulthood (per unit increase; OR 0.93, 95% CI 0.90 to 0.96) although fathers BMI when the child was aged 10 was positively associated with high TV in adulthood (per unit increase; OR 1.04, 95% CI 1.02 to 1.06). Conclusions Findings suggest that childhood TV viewing time tracks into adulthood. Parents’ health behaviours and social position appear to be associated with their children's viewing habits, which may have important implications for the direction of future policy and practice. Specifically, findings support the case for early life interventions, particularly on socioeconomic inequalities, as a way of preventing sedentary behaviour in later life. PMID:25147213

Smith, L; Gardner, B; Hamer, M

2015-01-01

438

The Functional, Social and Economic Impact of Acute Encephalitis Syndrome in Nepal – a Longitudinal Follow-Up Study  

PubMed Central

Background Over 133,000 children present to hospitals with Acute Encephalitis Syndrome (AES) annually in Asia. Japanese encephalitis (JE) accounts for approximately one-quarter of cases; in most cases no pathogen is identified and management is supportive. Although JE is known to result in neurological impairment, few studies have examined the wider impact of JE and AES on patients and their families. Methodology/Principal Findings Children (aged 1 month–14 years) with AES were assessed 5–12 months after discharge from two Nepali hospitals. Assessment included clinical examination, the Liverpool Outcome Score (LOS) - a validated assessment of function following encephalitis, questionnaires about the child's social participation since discharge, and out-of-pocket costs to the family. Children were classified as JE or ‘other AES’ based on anti-JE virus antibody titres during acute illness. Contact was made with the families of 76% (73/96) of AES children. Six children had died and one declined participation. 48% (32/66) reported functional impairment at follow-up, most frequently affecting behaviour, language or limb use. Impairment was more frequent in JE compared to ‘other AES’ cases (68% [13/19] versus 40% [19/47]; p?=?0.06). 49% (26/53) had improvement in LOS between discharge and follow-up. The median out-of-pocket cost to families, including medical bills, medication and lost earnings was US$ 1151 (10 times their median monthly income) for children with severe/moderate impairment and $524 (4.6 times their income) for those with mild/no i