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Ten Year Follow-up Study of 65 Suicidal Adolescents  

PubMed Central

Introduction: This survey studies the 10 year psychosocial outcome of 65 adolescents admitted to the Nancy Children’s Hospital in 1994 after a suicide attempt. Method: survey conducted using a self-assessment questionnaire sent to adolescents and their parents. Results: The response rate was 55.4%. About seventy per cent (70.5%) of respondents stated they were happy in their affective lives 10 years after the reference attempt, almost 70% (67.6%) had a job, nearly three quarters (72.5%) considered that they were in good health and 59% felt happy. More than half (55%) had made a subsequent suicide attempt. Two patients committed suicide. The originality of this study lies in its methodology since it allows, through comparison of suicide attempters’ responses with medical data, a high level of under-declaration of repeated attempts to be detected (41.2%). Statistical study of the associations between the total number of repeated suicide attempts and demographic characteristics of the initial population nonetheless evidenced that patients with a history of suicide attempts and those with a history of early repeated attempts (within three months and/or the year) were significantly more likely to repeat their attempt within ten years. Conclusion: Most of the 34 patients traced seemed to have satisfactory personal and professional lives, in contrast to the high level of repeated suicide attempts. Repeated suicide attempts during adolescence appear to be one of the major risk factors in attempting suicide again within 10 years. This confirms the importance of preventive measures after a first suicide attempt.

Gehin, Anouk; Kabuth, Bernard; Pichene, Catherine; Vidailhet, Colette



Ten Years Later: A Follow-Up Study of Professors Still Working after Age 70  

ERIC Educational Resources Information Center

Little is known about the impact of the end of mandatory retirement on professors over the long term. This follow-up study investigated the ten-year experience of professors who chose not to retire from a major research university after the elimination of the age 70 mandatory retirement in 1994. The initial interview study was conducted in 1998…

Dorfman, Lorraine T.



To What Extent is Research Utilized? A Ten-Year Follow-Up Study  

ERIC Educational Resources Information Center

Survey procedures in the follow-up study included notes in rehabilitation journals, questionnaires to persons requesting information on the Scale, and a literature search. Most informative results came from the questionnaire responses. (EA)

Bolton, Brian; Soloff, Asher



Radiological progression and lung function in silicosis: a ten year follow up study.  

PubMed Central

Chest radiographs and spirometric tests were performed on 81 patients who had silicosis from two granite quarries in 1975, 73 of whom were followed up for two to 10 (mean 7.2) years. Each patient's initial and most recent chest radiographs were assessed independently by three experienced readers, and the yearly declines in forced expiratory volume in one second and forced vital capacity were estimated from two to four (mean 3.45) serial spirometric readings. Estimates of individual dust exposure were based on extensive historical data on hygiene. All but 11 patients were no longer exposed to dust by the start of follow up, but 24 (45%) of 53 patients who had simple silicosis and 11 (55%) of 20 who had the complicated disease showed radiological evidence of disease progression. In patients who had simple silicosis and showed no radiological progression the yearly declines in forced expiratory volume in one second and forced vital capacity were modest (64 ml/year and 59 ml/year, respectively), whereas significantly greater declines in lung function were seen in those who showed radiological evidence of progression (97 ml/year and 95 ml/year, respectively). In addition to radiological progression the previous average dust concentration to which patients had been exposed also influenced declines in both forced expiratory volume in one second and forced vital capacity after allowing for the effects of age, smoking, duration of exposure, history of tuberculosis, initial state of disease, and baseline lung function. The probability of radiological progression was most strongly influenced by the average dust concentration previously exposed to. The progression of simple silicosis is thus accompanied by appreciable declines in lung function and is strongly affected by previous levels of exposure to dust.

Ng, T P; Chan, S L; Lam, K P



Ten-year follow-up of an anatomical hydroxyapatite-coated total hip prosthesis  

Microsoft Academic Search

We report our results after ten year follow-up of 107 consecutive ABG-I hip prostheses implanted between June 1990 and December 1992: Only 84 prostheses were still in the study after ten years, but only six patients had undergone surgical revision. We can consider our clinical outcomes as excellent, with a whole-implant survival rate greater than 96%, a mean Merle D’Aubigne

V. Canales Cortés; J. J. Panisello Sebastiá; A. Herrera Rodríguez; A. Peguero Bona; A. Martínez Martín; L. Herrero Barcos; L. García-Dihinx



Clinical and radiographic outcomes of acetabular impaction grafting without cage reinforcement for revision hip replacement: a minimum ten-year follow-up study.  


Impaction bone grafting for the reconstitution of bone stock in revision hip surgery has been used for nearly 30 years. Between 1995 and 2001 we used this technique in acetabular reconstruction, in combination with a cemented component, in 304 hips in 292 patients revised for aseptic loosening. The only additional supports used were stainless steel meshes placed against the medial wall or laterally around the acetabular rim to contain the graft. All Paprosky grades of defect were included. Clinical and radiographic outcomes were collected in surviving patients at a minimum of ten years after the index operation. Mean follow-up was 12.4 years (sd 1.5) (10.0 to 16.0). Kaplan-Meier survival with revision for aseptic loosening as the endpoint was 85.9% (95% CI 81.0 to 90.8) at 13.5 years. Clinical scores for pain relief remained satisfactory, and there was no difference in clinical scores between cups that appeared stable and those that appeared radiologically loose. PMID:24493183

Gilbody, J; Taylor, C; Bartlett, G E; Whitehouse, S L; Hubble, M J W; Timperley, A J; Howell, J R; Wilson, M J



Auditory and visual health after ten years of exposure to metal-on-metal hip prostheses: a cross-sectional study follow up.  


Case reports of patients with mal-functioning metal-on-metal hip replacement (MoMHR) prostheses suggest an association of elevated circulating metal levels with visual and auditory dysfunction. However, it is unknown if this is a cumulative exposure effect and the impact of prolonged low level exposure, relevant to the majority of patients with a well-functioning prosthesis, has not been studied. Twenty four male patients with a well-functioning MoMHR and an age and time since surgery matched group of 24 male patients with conventional total hip arthroplasty (THA) underwent clinical and electrophysiological assessment of their visual and auditory health at a mean of ten years after surgery. Median circulating cobalt and chromium concentrations were higher in patients after MoMHR versus those with THA (P<0.0001), but were within the Medicines and Healthcare Products Regulatory Agency (UK) investigation threshold. Subjective auditory tests including pure tone audiometric and speech discrimination findings were similar between groups (P>0.05). Objective assessments, including amplitude and signal-to-noise ratio of transient evoked and distortion product oto-acoustic emissions (TEOAE and DPOAE, respectively), were similar for all the frequencies tested (P>0.05). Auditory brainstem responses (ABR) and cortical evoked response audiometry (ACR) were also similar between groups (P>0.05). Ophthalmological evaluations, including self-reported visual function by visual functioning questionnaire, as well as binocular low contrast visual acuity and colour vision were similar between groups (P>0.05). Retinal nerve fibre layer thickness and macular volume measured by optical coherence tomography were also similar between groups (P>0.05). In the presence of moderately elevated metal levels associated with well-functioning implants, MoMHR exposure does not associate with clinically demonstrable visual or auditory dysfunction. PMID:24621561

Prentice, Jennifer R; Blackwell, Christopher S; Raoof, Naz; Bacon, Paul; Ray, Jaydip; Hickman, Simon J; Wilkinson, J Mark



Ten-year follow-up of an anatomical hydroxyapatite-coated total hip prosthesis  

PubMed Central

We report our results after ten year follow-up of 107 consecutive ABG-I hip prostheses implanted between June 1990 and December 1992: Only 84 prostheses were still in the study after ten years, but only six patients had undergone surgical revision. We can consider our clinical outcomes as excellent, with a whole-implant survival rate greater than 96%, a mean Merle D’Aubigne and Postel score increasing from 7.97 before operation to 16.17 at ten year follow-up, and a personal subjective assessment as excellent or good in 82.14% of patients. However, radiographic outcomes are more worrying: around 90% of patients show a stress-shielding phenomenon and granulomatous lesions in the proximal femur, and more than 82% suffer polyethylene wear greater than one  millimetre (mean 1.68 mm). We think that zirconia stem heads and hooded antiluxation PE inserts are determining factors in the process of PE wear and, secondarily, in cancellous bone resorption and bone osteolysis.

Panisello Sebastia, J. J.; Herrera Rodriguez, A.; Peguero Bona, A.; Martinez Martin, A.; Herrero Barcos, L.; Garcia-Dihinx, L.



Reading and writing difficulties in adolescence and later risk of welfare dependence. A ten year follow-up, the HUNT Study, Norway  

PubMed Central

Background Welfare dependence and low work participation among young people have raised concern in many European countries. Reading and writing difficulties (RWD) might make young people vulnerable to work integration problems and welfare dependence through negative influences on education and health. Our main objective of this study was to examine if RWD in adolescence affected the risk of welfare dependence in young adulthood. Methods Baseline information on self-reported RWD, health and family was obtained for 8950 school-attending adolescents in Nord-Trøndelag County, Norway, participating in the Young-HUNT1 survey, 1995-97. All individuals were linked to biological parents to identify siblings and parental education from national registers. Welfare dependence was assessed by the reception of social benefits (medical and economic) from the national social insurance database (1998-2007). Only long-term benefits (> 180 days) were included. Results The adolescents who reported RWD at baseline were more likely to receive medical or social benefits during follow-up compared with those who did not report RWD. In girls with RWD, the adjusted 5-year risk (at age 24 to 28) for receiving medical benefits was 0.20 (95% confidence interval 0.14-0.26), compared with 0.11 (0.09-0.12) in girls without RWD. In boys the corresponding risks were 0.13 (0.09-0.17) and 0.08 (0.07-0.09). Conclusions The associations between RWD in adolescence and welfare dependence later in life suggest that increased attention should be paid to these problems when discussing the public health aspects of work integration, since there might be a potential for prevention.



Ten year follow up study of lymphocytic gastritis: further evidence on Helicobacter pylori as a cause of lymphocytic gastritis and corpus gastritis.  

PubMed Central

AIMS--To examine the course of lymphocytic gastritis and its relation to Helicobacter pylori (H pylori) infection in a 10 year follow up. METHODS--Ninety six patients were originally examined for dyspepsia in 1981. Gastroscopies with stepwise biopsies were performed on all the patients initially and after an interval of 10 years. RESULTS--Nine per cent of the patients (9/96) had features of lymphocytic gastritis in gastric biopsy at the first examination, and 12.5% (12/96) at the second examination; 7/9 patients (78%) had persistent lymphocytic gastritis during the follow up; in two the diagnostic features of lymphocytic gastritis had disappeared, and five had a new diagnosis of lymphocytic gastritis at the second examination. At the second examination 9/12 lymphocytic gastritis patients (75%) were H pylori positive histologically, while all had specific antibodies to H pylori. The lymphocytic gastritis patients had higher grades of gastritis (p = 0.009), neutrophilic and eosinophilic granulocytes, mononuclear inflammatory cells, and foveolar hyperplasia in the corpus mucosa, but smaller numbers of H pylori, than the H pylori positive patients without lymphocytic gastritis. The appearance of lymphocytic gastritis during the 10 year interval was associated with increases in the grades of corpus gastritis and neutrophilic granulocytes (p = 0.043 for both). During the follow up, the patients with lymphocytic gastritis, but not the H pylori positive patients without lymphocytic gastritis, appeared to have a significant increase in the grade of intestinal metaplasia in the corpus mucosa (p = 0.043). CONCLUSIONS--In some patients H pylori may cause a gastritis that predominates in the corpus and is associated with an increase in the intraepithelial lymphocyte count. This form of gastritis may cause progression of intestinal metaplasia. Images

Niemela, S; Karttunen, T; Kerola, T; Karttunen, R



Leukemia in women following radiotherapy for cervical cancer: ten-year follow-up of an international study. [External Radiation or Radium implant  

SciTech Connect

An international collaborative study, with 69 references, of 31,219 women treated for cervical cancer from 30 radiotherapy centers in nine countries was conducted. Patients were followed clinically and with blood studies between 1960 and 1970, and 148,000 woman-years (WY) were accumulated. Among 28,490 women treated with either intercavitary radium, external radiation, or both, 134,000 WY were accumulated and 13 cases of leukemia were observed. On the basis of general population rates, 15.5 cases were expected. A twofold risk could thus be excluded, but a 1.4-fold risk remained possible. In absolute terms, risks larger than 0.1 leukemia cases per 10/sup 6/ WY-rad could be excluded. Among 2,729 cervical cancer patients not irradiated but similarly evaluated, 14,000 WY were accumulated and 2 cases of leukemia were observed as compared with 1.0 expected. In the interval 4-8 years after exposure, the period in which any leukemogenic effect might be most apparent, 7 cases of leukemia were observed among exposed patients as compared with 5.4 expected. The absence of an increased leukemia risk suggested that the radiation regimens used to treat cervical cancer are not so effective in inducing leukemia as are other radiation exposures that have been studied.

Boice, J.D. (National Institutes of Health, Bethesda, MD); Hutchison, G.B.



Ten-Year Follow-Up of Endovascular Aneurysm Treatment with Talent Stent-Grafts  

SciTech Connect

The purpose of this study was to evaluate the clinical results, complications, and secondary interventions during long-term follow-up after endovascular aneurysm repair (EVAR) and to investigate the impact of endoleak sizes on aneurysm shrinkage. From 1997 to March 2007, 127 patients (12 female, 115 male; age, 73.0 {+-} 7.2 years) with abdominal aortic aneurysms were treated with Talent stent-grafts. Follow-up included clinical visits, contrast-enhanced MDCT, and radiographs at 3, 6, and 12 months and then annually. Results were analyzed with respect to clinical outcome, secondary interventions, endoleak rate and management, and change in aneurysm size. There was no need for primary conversion surgery. Thirty-day mortality was 1.6% (two myocardial infarctions). Procedure-related morbidity was 2.4% (paraplegia, partial infarction of one kidney, and inguinal bleeding requiring surgery). Mean follow-up was 47.7 {+-} 34.2 months (range, 0-123 months). Thirty-nine patients died during follow-up; three of the deaths were related to aneurysm (aneurysm rupture due to endoleak, n = 1; secondary surgical reintervention n = 2). During follow-up, a total of 29 secondary procedures were performed in 19 patients, including 14 percutaneous procedures (10 patients) and 15 surgical procedures (12 patients), including 4 cases with late conversion to open aortic repair (stent-graft infection, n = 1; migration, endoleak, or endotension, n = 3). Overall mean survival was 84.5 {+-} 4.7 months. Mean survival and freedom from any event was 66.7 {+-} 4.5 months. MRI depicted significantly more endoleaks compared to MDCT (23.5% vs. 14.3%; P < 0.01). Patients in whom all aneurysm side branches were occluded prior to stent-grafting showed a significantly reduced incidence of large endoleaks. Endoleaks >10% of the aneurysm area were associated with reduced aneurysm shrinkage compared to no endoleaks or <10% endoleaks ({Delta} at 3 years, -1.8% vs. -12.0%; P < 0.05). In conclusion, endovascular aneurysm treatment with Talent stent-grafts demonstrated encouraging long-term results with moderate secondary intervention rates. Primary occlusion of all aortic side branches reduced the incidence of large endoleaks. Large endoleaks significantly impaired aneurysm shrinkage, whereas small endoleaks did not.

Pitton, Michael B., E-mail:; Scheschkowski, Tobias; Ring, Markus; Herber, Sascha; Oberholzer, Katja; Leicher-Dueber, Annegret [University Hospital of Mainz, Johannes Gutenberg University of Mainz, Department of Diagnostic and Interventional Radiology (Germany); Neufang, Achim; Schmiedt, Walther [University Hospital of Mainz, Johannes Gutenberg University of Mainz, Department of Cardiovascular and Thoracic Surgery (Germany); Dueber, Christoph [University Hospital of Mainz, Johannes Gutenberg University of Mainz, Department of Diagnostic and Interventional Radiology (Germany)



Ten-year follow up after laparoscopic Nissen fundoplication for gastroesophageal reflux disease.  


Laparoscopic Nissen fundoplication was first undertaken in the early 1990s. Appreciable numbers of patients with 10-year follow up are only now available. This study assesses long-term outcome and durability of outcome after laparoscopic Nissen fundoplication for treatment of gastro-esophageal reflux disease. Since 1991, 829 patients have undergone laparoscopic fundoplications and are prospectively followed. Two hundred thirty-nine patients, 44 per cent male, with a median age of 53 years (+/- 15 standard deviation) underwent laparoscopic Nissen fundoplications at least 10 years ago; 28 (12%) patients were "redo" fundoplications. Before and after fundoplication, among many symptoms, patients scored the frequency and severity of dysphagia, chest pain, vomiting, regurgitation, choking, and heartburn using a Likert scale (0 = never/not bothersome to 10 = always/very bothersome). Symptom scores before versus after fundoplication were compared using a Wilcoxon matched-pairs test. Data are reported as median, mean +/- standard deviation, when appropriate. After fundoplication, length of stay was 2 days, 3 days +/- 4.8. Intra-operative inadvertent events were uncommon and without sequela: 1 esophagotomy, 1 gastrotomy, 3 cardiac dysrhythmias, and 3 CO2 pneumothoraces. Complications after fundoplication included: 1 postpneumonic empyema, 3 urinary retentions, 2 superficial wound infections, 1 urinary tract infection, 1 ileus, and 1 intraabdominal abscess. There were two perioperative deaths; 88 per cent of the patients are still alive. After laparoscopic Nissen fundoplication, frequency and severity scores dramatically improved for all symptoms queried (P < 0.001), especially for heartburn frequency (8, 8 +/- 3.2 versus 2, 3 +/- 2.8, P < 0.001) and severity (10, 8 +/- 2.9 versus 1, 2 +/- 2.5, P < 0.001). Eighty per cent of patients rate their symptoms as almost completely resolved or greatly improved, and 85 per cent note they would again have the laparoscopic fundoplication as a result of analysis of our initial experience, thereby promoting superior outcomes in the future. Nonetheless, follow up at 10 years and beyond of our initial experience documents that laparoscopic fundoplication durably provides high patient satisfaction resulting from long-term amelioration of the frequency and severity of symptoms of gastroesophageal reflux disease. These results promote further application of laparoscopic Nissen fundoplication. PMID:17879678

Cowgill, Sarah M; Gillman, Rachel; Kraemer, Emily; Al-Saadi, Sam; Villadolid, Desiree; Rosemurgy, Alexander



Carpentier-Edwards pericardial valves in the mitral position: Ten-year follow-up  

Microsoft Academic Search

Objective: The first generation of pericardial valves was withdrawn from the market because of a high rate of premature failure. With an original design, Carpentier-Edwards pericardial valves promised improved results.Methods: One hundred fifty patients who underwent isolated mitral valve replacement, between July 1984 and December 1993, with Carpentier-Edwards pericardial bioprostheses in our institution were followed up. Patient mean age was

M. R. Aupart; P. H. Neville; S. Hammami; A. L. Sirinelli; Y. A. Meurisse; M. A. Marchand



Children of divorce: report of a ten-year follow-up of early latency-age children.  


Findings from a ten-year follow-up of 38 youngsters now 16 to 18 years old, whose parents divorced during the children's early latency, suggest that separation from families and the transition into young adulthood are burdened by fear of disappointment in love relationships, lowered expectations, and a sense of powerlessness. A need for the father, especially among boys, appears to burgeon at middle and late adolescence. PMID:3591906

Wallerstein, J S



Gastrointestinal Involvement in Lipoid Proteinosis: A Ten-Year Follow-Up of a Brazilian Female Patient  

PubMed Central

Lipoid proteinosis is a rare autosomal recessive disease characterized by the deposition of hyaline material in the skin and internal organs. The main clinical features are hoarseness and typical skin lesions. In this report we describe the endoscopic and radiologic findings in a Brazilian female patient presenting extensive gastrointestinal involvement and the evolution of the detected lesions in ten years of follow-up. Initial upper endoscopy and colonoscopy showed a similar pattern of multiple yellowish nodules throughout the esophagus, stomach, duodenum, and colons. Histological analysis confirmed the diagnosis of lipoid proteinosis. In addition, small bowel follow through demonstrated numerous well defined, round, small filling defects throughout the jejunum. Ten years later, the esophageal lesions remained the same, but none of the previous alterations were detected in the stomach, duodenum, and colons. In conclusion, lipoid proteinosis may affect all gastrointestinal organs with the same pattern of macroscopic and microscopic lesions. Some lesions may regress with increasing age.

Custodio Lima, Juliana; Nagasako, Cristiane Kibune; Montes, Ciro Garcia; Barcelos, Irene Harumi Kamata; de Carvalho, Rita Barbosa



Emerging pathogens in cystic fibrosis: ten years of follow-up in a cohort of patients.  


In patients with cystic fibrosis (CF), there is an increasing incidence of some uncommon respiratory pathogens, such as Burkholderia cepacia complex (Bcc), Stenotrophomonas maltophilia, and Achromobacter xylosoxidans. In order to evaluate the prevalence and the clinical impact of these pathogens, we retrospectively studied a total of 109 patients followed in our center from 1996 to 2006 and reviewed the results of 1,550 sputum samples. The isolation of Pseudomonas aeruginosa slightly decreased over the observed decade, whereas Staphylococcus aureus exhibited an irregular trend. Infection with Bcc reached a peak in 1998 and successively decreased to a stable 4%. S. maltophilia and A. xylosoxidans were the real emerging pathogens, since first isolation occurred in 2004; however, the percentage of infected patients remained low (7% and 3.2%, respectively) through the years. In conclusion, in our center for CF, the reduced prevalence of P. aeruginosa over the last decade has been associated with a concurrent reduction of infections by Bcc and, as compared to other centers in Italy, Europe, and the US, with a low incidence of emerging pathogens such as S. maltophilia and A. xylosoxidans. PMID:18758832

Spicuzza, L; Sciuto, C; Vitaliti, G; Di Dio, G; Leonardi, S; La Rosa, M



Collarless polished tapered stem: clinical and radiological results at a minimum of ten years' follow-up.  


We retrospectively reviewed 175 patients (191 hips) who had undergone primary cemented total hip replacement between November 1992 and November 1995 using a collarless polished double-tapered femoral component after a minimum of ten years (mean 11.08; 10 to 12.8). All stems were implanted using contemporary cementing techniques with a distal cement restrictor, pressurised lavage, retrograde cementing with a gun and proximal pressurisation. Clinical outcome was assessed using the Harris Hip score. Radiological analysis was performed on calibrated plain radiographs taken in two planes. Complete radiological data on 110 patients (120 hips) and clinical follow-up on all the surviving 111 patients (122 hips) was available. The fate of all the hips was known. At final follow-up, the mean Harris Hip score was 86 (47 to 100), and 87 of 116 patients (75%) had good or excellent scores. Survival with revision of the stem for aseptic loosening as the endpoint was 100%; and survival with revision of the stem for any reason was 95.9% (95% confidence interval 87.8 to 96.8) at ten years. All the stems subsided vertically at the stem-cement interface in a predictable pattern, at an overall mean rate of 0.18 mm per year (0.02 to 2.16), but with a mean rate of 0.80 mm (0.02 to 2.5) during the first year. The mean total subsidence was 1.95 mm (0.21 to 24). Only three stems loosened at the cement-bone interface. There was excellent preservation of proximal femoral bone stock. There was a high incidence of Brooker III and IV heterotopic ossification affecting 25 patients (22%). The collarless polished tapered stem has an excellent clinical and radiological outcome at a minimum of ten years' follow-up. The pattern and magnitude of subsidence of the stem within the cement mantle occurred in a predictable pattern, consistent with the design philosophy. PMID:18160493

Yates, P J; Burston, B J; Whitley, E; Bannister, G C



Carcinoma in situ of urinary bladder: incidence, treatment and clinical outcomes during ten-year follow-up.  


Bladder carcinoma in situ (CIS) is a rare, high-grade intraepithelial neoplasm with a high tendency of progression and unpredictable clinical course. The aim of this study was to evaluate the incidence, treatment and clinical outcome of patients with CIS during a 10-year period. Medical records of 1062 patients with primary bladder cancer and 847 patients with recurrent bladder cancer that underwent tumor resection at Department of Urology, Split University Hospital Center, Split, Croatia, between January 2001 and December 2010, were analyzed. Among all treated patients with primary bladder neoplasms, 51 (4.8%) had CIS. Primary CIS was diagnosed in 18 (1.7%) and concomitant CIS in 33 (3.1%) patients. In the same period, 847 patients with recurrent tumors were treated by transurethral resection (TUR), 12 (1.4%) of them with secondary CIS. Clinical course was followed-up in 15 patients with primary CIS and 21 patients with concomitant (TaT1) CIS. BCG immunotherapy was applied in 12 patients with primary and 17 patients with concomitant CIS. After median follow-up of 50 months, 9 patients with primary CIS had no sign of disease, 4 progressed, 1 had recurrence and 1 died. After median follow-up of 37 months, 13 (62%) patients with concomitant CIS had complete response, 3 progressed (14%), 1 had recurrence (4%) and 4 patients died, however, only 2 (10%) of these due to bladder cancer. Of all patients receiving BCG immunotherapy, 8 (27%) had significant side effects. The incidence and treatment of patients with CIS of urinary bladder in our institution is comparable to other recent literature reports. PMID:23115943

Librenjak, Davor; Novakovi?, Zana Saratlija; Milosti?, Kazimir



Home Environment and School Performance: A Ten-Year Follow-up and Examination of Three Models of Environmental Action.  

ERIC Educational Resources Information Center

Examines home environments of children aged ten and eleven when they were six months and two years old. Significant correlations were observed between the home environments at two and ten years, children's achievement test scores, and classroom behavior. Home environment at six months was related to a minimal number of classroom behaviors. (RJC)

Bradley, Robert H.; And Others



Endoscopically-assisted single-bundle posterior cruciate ligament reconstruction: results at minimum ten-year follow-up.  


We evaluated the long-term outcome of isolated endoscopically-assisted posterior cruciate ligament reconstruction in 26 patients using hamstring tendon autografts after failure of conservative management. At ten years after surgery the mean International Knee Documentation Committee subjective knee score was 87 (SD 14) of a possible 100 points. Regular participation in moderate to strenuous activities was possible for only seven patients pre-operatively; this increased to 23 patients post-operatively. The mean Lysholm score improved from 64 (SD 15) to 90 (SD 14) at ten years (p = 0.001). At ten years endoscopic reconstruction of the posterior cruciate ligament with hamstring tendon autograft is effective in reducing knee symptoms. Of the series, 22 patients underwent radiological assessment for the development of osteoarthritis using the Kellgren-Lawrence grading scale. In four patients, grade 2 changes with loss of joint space was observed and another four patients showed osteophyte formation with moderate joint space narrowing (grade 3). These findings compared favourably with non-operatively managed injuries of the posterior cruciate ligament. This procedure for symptomatic patients with posterior cruciate ligament laxity who have failed conservative management offers good results. PMID:18827243

Jackson, W F M; van der Tempel, W M; Salmon, L J; Williams, H A; Pinczewski, L A



Anatomical risk factors in primary angle-closure glaucoma. A ten year follow up survey based on limbal and axial anterior chamber depths in a high risk population.  


A population of 539 persons was examined in 1979, using LCD and ACD estimations acc. to van Herick et al. and by Haag Streit pachymetry, respectively. ACD had been measured already in 1969, due to a remarkable occurrence of primary angle-closure glaucoma (PACG) in the survey population of Greenland Eskimos (District of Uummannaq). The present follow up study in 1989 aimed at persons presently above age 40, who had shown either an LCD value graded as 0 (contact) or 1 (< 0.25 of corneal thickness = CT), or a value of 2 (= 0.25 CT) if an ACD value of < = 2.70 mm (CT included) had also been found. PACG patients or suspects known in 1979 already were excluded from the present analyses. A total of 75 persons was now examined. Five had developed acute (n = 2) or intermittent PACG (n = 3) during the ten year period. At the survey 3 intermittent and 4 latent PACG cases were detected, yielding in ten years a PACG prevalence of 12/75 = 16% (sex ratio: M/F = 2/10). One male case of severe secondary (partly inflammatory) ACG was also found. Past and present LCD and ACD values are given as well as gonioscopical status. Creeping, synechial angle-closure was frequent. Among probands who could not be examined, mostly due to death before 1989, 5/54 had developed PACG during the ten year period. Non-probands according to above criteria were mostly not examined. Yet their records were scrutinized for any event suspect of PACG. Thus among 258 persons above age 40 no PACG case was found.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:1428555

Alsbirk, P H



Excellent results with cementless total hip arthroplasty and alumina-on-alumina pairing: minimum ten-year follow-up.  


Ceramic-on-ceramic coupling is thought to be a durable alternative to metal- or alumina-on-polyethylene pairing. No evidence exists suggesting superior clinical and radiological results for hydroxyapatite-coated stems versus uncoated stems. The aim of this study is to report the performance of an alumina-on-alumina bearing cementless total hip arthroplasty and to compare stems with a tapered design with and without hydroxyapatite coating. We prospectively analysed the results of cementless tapered femoral stems (40 hydroxyapatite-coated versus 22 uncoated stems), a metal-backed fibre mesh hydroxyapatite-coated socket and alumina-on-alumina pairing. Of 75 hips studied, 62 were available for follow-up (mean of 10.5 years after surgery). The average Harris hip score was 90. Only one hydroxyapatite-coated stem was revised for aseptic loosening. One instance of non-progressive osteolysis was detected around a screw of a cup. All other components showed radiographic signs of stable ingrowth. Hydroxyapatite coating of the stem had no significant impact on the clinical or radiological results. Total hip arthroplasty with the presented implant and pairing provides a durable standard for all patients requiring hip joint replacement against which all newer generations of cementless implants should be judged. PMID:21079952

Kress, Alexander M; Schmidt, Rainer; Holzwarth, Ulrich; Forst, Raimund; Mueller, Lutz A



Firework injuries: a ten-year study.  


Fireworks are used worldwide to celebrate popular events (e.g. festivals, official celebrations, weddings). The festival of lights (Diwali) is celebrated with fireworks in India. During this period, many patients from all age groups present to hospital with injuries due to fireworks. Prevalence, period of occurrence, sex and age variation, adult supervision, causative fireworks, mode of lighting, age groups prone to injury, patterns of injury caused by individual fireworks, and the body parts injured were studied. One hundred and fifty-seven cases (92 retrospective, 65 prospective) with injury due to fireworks presenting to the Department of Plastic Surgery at KEM Hospital between 1997 and 2006 were studied. The prevalence of injuries has decreased steadily over the last 10 years (41 cases in 1997, 3 cases in 2006). The maximum number of injuries (35%) was seen in the age group 5-14 years; 92% of these children were unsupervised. The commonest cause of injury was firework misuse (41% of cases), followed by device failure (35%). Device failure was commonest with flares/fountains (ground firework emitting sparks upwards) and aerial devices. Flare/fountains caused most injury (39%), sparklers the least (0.6%). Flare/fountains, ground spinners, sparklers, and gunpowder (explosive material from cracker, obtained by tearing paper wrapper and obtaining chemicals) caused only soft tissue burns; stringbombs (high-intensity fire cracker made by wrapping chemicals with jute strings/coir in layers) and rockets (aerial device that zooms upwards and bursts) caused blast injuries, leading to soft tissue disruption and bony injuries. Emergency surgery was done if indicated: tendon and/or neurovascular repair, fracture fixation, flap cover or amputation. Superficial burns were treated with dressings. Certain wounds needed only thorough cleansing of the wound and primary suturing. We concluded that, over a 10-year period, the prevalence of firework injury decreased due to increased awareness in the community. Aggressive awareness campaigns by government and non-government organisations was the cause. We can minimise the number and severity of accidents by raising awareness regarding safety precautions, encouraging professional displays and motivating manufacturers to adhere to strict quality control. PMID:18603491

Puri, Vinita; Mahendru, Sanjay; Rana, Roshani; Deshpande, Manish



Construction work and risk of occupational disability: a ten year follow up of 14 474 male workers  

PubMed Central

Aims: Most industrialised countries have public income maintenance programmes to protect workers in case of disability but studies addressing disability risk of specific professional groups are rare. The objective of this study was to establish a detailed pattern of the nature and extent of occupational disability among construction workers. Methods: A cohort study was set up including 14 474 male workers from the construction industry in Württemberg (Germany) aged 25–64 years who underwent occupational health exams between 1986 and 1992. The cohort was linked to the regional pension register of the manual workers' pension insurance institution to identify workers who were granted a disability pension during the 10 year follow up. All-cause and cause specific standardised incidence ratios (SIR) and 95% confidence intervals (CI) were calculated using disability rates from the general workforce and from all blue collar workers in Germany as references. Results: In total, 2247 (16%) members of the cohort were granted a disability pension. Major causes of disability were musculoskeletal (45%) and cardiovascular diseases (19%). In comparison with the general workforce, construction workers experienced a higher risk of disability from cancer (SIR = 1.26; 95% CI 1.08 to 1.47), respiratory diseases (SIR = 1.27; 95% CI 1.03 to 1.55), musculoskeletal diseases (SIR = 2.16; 95% CI 2.03 to 2.30), injuries/poisoning (SIR = 2.52; 95% CI 2.06 to 3.05), and all causes combined (SIR = 1.47; 95% CI 1.41 to 1.53). When compared with the blue collar reference group, increased risks of disability among construction workers were found for musculoskeletal diseases (SIR = 1.53; 95% CI 1.44 to 1.63), injury/poisoning (SIR = 1.83; 95% CI 1.50 to 2.21), and all causes combined (SIR = 1.11; 95% CI 1.07 to 1.16). Conclusions: Musculoskeletal diseases and external causes are major factors limiting the work capability of construction workers and lead to an increased proportion of occupational disability.

Arndt, V; Rothenbacher, D; Daniel, U; Zschenderlein, B; Schuberth, S; Brenner, H



Ten-year follow-up of Parkinson's disease patients randomized to initial therapy with ropinirole or levodopa.  


In a 5-year, double-blind study, subjects with Parkinson's disease (PD) who were randomized to initial treatment with ropinirole had a significantly lower incidence of dyskinesia compared with subjects randomized to levodopa, although Unified Parkinson's Disease Rating Scale (UPDRS) motor scores were significantly more improved in the levodopa group. Subjects who completed the original study were eligible to participate in a long-term extension study conducted according to an open, naturalistic design and were evaluated approximately every 6 months until they had been followed for a total of 10 years. Comparing subjects randomized to initial treatment with ropinirole (n = 42) and levodopa (n = 27), the incidence of dyskinesia was significantly lower in the ropinirole group (adjusted odds ratio [OR] = 0.3; 95% confidence interval [CI]: 0.1, 1.0; P = 0.046) and the median time to dyskinesia was significantly longer (adjusted hazard ratio = 0.4; 95% CI: 0.2, 0.8; P = 0.007). The incidence of at least moderate wearing off ("off" time >/=26% of the awake day) was also significantly lower in the ropinirole group (adjusted OR = 0.3; 95% CI: 0.09, 0.03; P = 0.03). There were no significant differences in change in UPDRS activities of daily living or motor scores, or scores for the 39-item PD questionnaire, Clinical Global Impression, or the Epworth Sleepiness Scale. Early treatment decisions for individual patients depend largely on the anticipated risk of side effects and long-term complications. Both ropinirole and levodopa are viable treatment options in early PD. PMID:17894339

Hauser, Robert A; Rascol, Olivier; Korczyn, Amos D; Jon Stoessl, A; Watts, Ray L; Poewe, Werner; De Deyn, Peter P; Lang, Anthony E



Total body irradiation for stage II-IV non-Hodgkin's lymphoma: ten-year follow-up  

SciTech Connect

Between 1972 and 1977, a prospective study was conducted at the University of Florida on the role of total body irradiation (TBI) in the management of stage II-IV non-Hodgkin's lymphoma (NHL). Forty-four consecutive de novo (DN) patients (including ten stage II, 18 stage III, and 16 stage IV), as well as 16 previously treated (PT) patients, were accrued. Twenty of the 44 DN patients were symptomatic at presentation. Complete clinical responses were obtained in 20 of the 27 DN patients with favorable histologies (FH), and six of the 17 with unfavorable histologies (UH). Partial responses were obtained in six patients with FH and 11 patients with UH; only one patient showed no response to TBI. By univariate analysis, PT patients showed a trend for decreased relapse-free survival (P = .066) and decreased survival (P = .093). Multivariate analysis identified the best predictors of response rate to be histology (P = .0146) and marrow involvement (P = .0854); of relapse-free survival, histology (P = .0035), and TBI dose (P = .002); and of absolute survival, age (P = .0012), histology (P = .012), and TBI dose (P = .029). Thirty of the 41 patients who relapsed underwent salvage treatment with either chemotherapy or radiation. Twenty-three of the 30 undergoing salvage therapy obtained a second complete clinical response. There were no treatment-related deaths. The most common complication was thrombocytopenia. The major late complications were myeloproliferative disorders in four patients, which occurred only after cumulative TBI doses in excess of 200 cGy.

Mendenhall, N.P.; Noyes, W.D.; Million, R.R.



Longitudinal follow-up of patients with traumatic brain injury: outcome at two, five, and ten years post-injury.  


The deleterious consequences of traumatic brain injury (TBI) impair capacity to return to many avenues of pre-morbid life. However, there has been limited longitudinal research examining outcome beyond five years post-injury. The aim of this study was to examine aspects of function, previously shown to be affected following TBI, over a span of 10 years. One hundred and forty one patients with TBI were assessed at two, five, and 10 years post-injury using the Structured Outcome Questionnaire. Fatigue and balance problems were the most common neurological symptoms, with reported rates decreasing only slightly during the 10-year period. Mobility outcomes were good in more than 75% of patients, with few participants requiring aids for mobility. Changes in cognitive, communication, behavioral, and emotional functions were reported by approximately 60% of the sample at all time points. Levels of independence in activities of daily living were high during the 10-year period, and as many as 70% of subjects returned to driving. Nevertheless, approximately 40% of patients required more support than before their injury. Only half the sample returned to previous leisure activities and fewer than half were employed at each assessment time post-injury. Although marital status remained stable over time, approximately 30% of participants reported difficulties in personal relationships. Older age at injury did not substantially alter the pattern of changes over time, except in employment. Overall, problems that were evident at two years post-injury persisted until 10 years post-injury. The importance of these findings is discussed with reference to rehabilitation programs. PMID:23889321

Ponsford, Jennie L; Downing, Marina G; Olver, John; Ponsford, Michael; Acher, Rose; Carty, Meagan; Spitz, Gershon



Ten-year outcome of serum metal ion levels after primary total hip arthroplasty: a concise follow-up of a previous report*.  


We previously reported on the metal ion concentrations of cobalt, chromium, and titanium that were found in the serum of patients three years after they had undergone primary total hip arthroplasty as compared with the concentrations found in the serum of control patients who did not have an implant. This study is a concise update on the serum metal levels found in a cohort of these patients ten years after the time of hip implantation. Of the original seventy-five subjects, metal ion levels were available for forty patients (53%). Ten patients (hybrid group) had received a hybrid total hip replacement that consisted of a modular cobalt-alloy femoral stem with a cobalt-alloy femoral head that had been inserted with cement and a titanium acetabular socket that had been inserted without cement. Nine patients (cobalt-chromium [CoCr] group) had received an implant with an extensively porous-coated modular cobalt-alloy femoral stem and femoral head along with a titanium acetabular socket; the femoral and acetabular components had each been inserted without cement. Eight patients (titanium group) had undergone insertion of a proximally porous-coated modular titanium-alloy femoral stem with a cobalt-alloy femoral head and a titanium acetabular socket; the femoral and acetabular components had each been inserted without cement. Thirteen patients (control group) from the original control group of patients who had not received an implant served as control subjects. Serum metal levels were measured with use of high-resolution sector field inductively coupled plasma mass spectrometry. The hybrid total hip arthroplasty group had mean cobalt levels that were 3.2 times higher at 120 months than they were at baseline, and the cobalt levels in that group were significantly higher than those in the titanium total hip arthroplasty group at thirty-six, sixty, eighty-four, ninety-six, and 120 months (p < 0.01). The hybrid group had mean chromium levels that were 3.9 times higher at 120 months than they were at baseline, and the CoCr total hip arthroplasty group had chromium levels that were 3.6 times higher at 120 months than they were at baseline. The serum titanium levels were higher in the titanium group at all follow-up time intervals as compared with the levels in all other groups, and the level in the titanium group at 120 months was eighteen times higher than it was at baseline (p < 0.01). Patients with well-functioning primary metal-on-polyethylene total hip replacements had elevated serum metal levels for as many as ten years postoperatively. Furthermore, metal release at the modular femoral head-neck junctions, rather than passive dissolution from porous ingrowth surfaces, was likely the dominant source of serum cobalt and chromium. PMID:23515985

Levine, Brett R; Hsu, Andrew R; Skipor, Anastasia K; Hallab, Nadim J; Paprosky, Wayne G; Galante, Jorge O; Jacobs, Joshua J



Ten-year experience with endomyocardial biopsy in myocarditis presenting with congestive heart failure: frequency, pathologic characteristics, treatment and follow-up.  


The present study summarizes our ten-year (1985-1995) experience with endomyocardial biopsy (EMB) in patients with idiopathic congestive heart failure (CHF), with specific reference to frequency of myocarditis, treatment policy, relative benefits, and follow-up. Of the 601 patients who constituted our series, 38 were clinically suspected of having myocarditis on the bases of a very recent onset of congestive heart failure and/or of arrhythmias and/or of conduction disturbances, and of a close-to-recent history of flu-like febrile illness. Corresponding EMBs showed myocarditis in 16 of the 38 cases (42.1%). A further 10 EMBs, from patients with a recent onset of congestive heart failure without prior infection episodes, showed myocarditis. Therefore, biopsy-proven myocarditis occurred in 26 of the 601 patients (4.3%). Of the 26 cases, 21 were lymphocytic, 1 was necrotizing granulomatous, 1 was eosinophilic and occurred in a patient who later developed overt zoonosis, 1 had some giant cells within endocardial inflammatory infiltrates, and 2 were borderline forms. In active myocarditis, inflammatory cells mostly constituted of T-lymphocytes (CD45RO+) with sparse macrophages (CD68+) and a few B cells (CD20+). B-lymphocytes and macrophages, along with activated T-lymphocytes, all expressed MHC class II HLA DR molecules, which were also expressed "de novo" by activated endothelial calls of capillaries and of small intramural vessels. HLA DR revealed itself as a very useful marker for the detection of activated inflammatory and endothelial cells. We also noted an increase in the number of perivascular and interstitial mast cells. Ultrastructural study was helpful for the characterization of myocyte damage and of interactions between inflammatory cells and myocytes. In 4 cases (1 of whom was later revealed as HIV positive, and subsequently died of AIDS), we found microreticulotubular structures in endothelial cells of small vessel and capillaries; in 7 cases, there were myocyte changes similar to those described in polymyositis; in 1 case, we observed subplasmalemmal buddings, but no viral particles; in 6 cases, there was extensive myocyte damage with myofibrillar lysis and focal adipous metaplasia; the remaining 6 cases showed myocyte damage of differing extent and severity; in the borderline forms, such damage coexisted with interstitial fibrosis. One of the 21 lymphocytic myocardites was not treated because during hospital screening the patient proved to be HIV positive; of the remaining 20 active myocardites, 11 were treated with a 6-month tapered steroid and azathioprine protocol (one was treated for 24 months), while 9 were not treated. The corresponding follow-up was: 6 deaths (congestive heart failure), 2 cardiac transplants and 3 survivals (1 with pace-maker) in the treated group, and 3 deaths (2 of congestive heart failure and 1 of sudden death), 1 cardiac transplant and 5 survivals (1 on the waiting list for transplantation) in the non-treated group. One of the 2 patients with borderline myocarditis died of congestive heart failure, and 1 is alive. Of the 22 patients with clinical diagnosis of myocarditis and negative biopsy, 7 died of congestive heart failure (2 on the waiting list for transplantation), 4 underwent cardiac transplantation, and 11 are alive (1 is awaiting transplantation). Of the 20 patients currently alive, 1 was originally in NYHA class III, 15 were in class II and 4 were in class I. Of the 20 overall patients who died, 12 were originally in NYHA class IV, 6 in class III, 2 in class II; of the 8 patients who underwent transplantation, 6 were originally in NYHA class IV and 2 in class III. Our overall experience shows that the frequency of myocarditis diagnosed according to Dallas criteria is high in patients with clinical diagnosis of myocarditis, while it is extremely low in dilated cardiomyopathy patients. This finding suggests that, although non-specific, recent onset of symptoms and prior febrile infe PMID:9199949

Arbustini, E; Gavazzi, A; Dal Bello, B; Morbini, P; Campana, C; Diegoli, M; Grasso, M; Fasani, R; Banchieri, N; Porcu, E; Pilotto, A; Ponzetta, M; Bellini, O; Lucreziotti, S; Viganò, M



Grafting with hydroxyapatite granules for defects of acetabular bone at revision total hip replacement: a minimum ten-year follow-up.  


The long-term results of grafting with hydroxyapatite granules for acetabular deficiency in revision total hip replacement are not well known. We have evaluated the results of revision using a modular cup with hydroxyapatite grafting for Paprosky type 2 and 3 acetabular defects at a minimum of ten years' follow-up. We retrospectively reviewed 49 acetabular revisions at a mean of 135 months (120 to 178). There was one type 2B, ten 2C, 28 3A and ten 3B hips. With loosening as the endpoint, the survival rate was 74.2% (95% confidence interval 58.3 to 90.1). Radiologically, four of the type 3A hips (14%) and six of the type 3B hips (60%) showed aseptic loosening with collapse of the hydroxyapatite layer, whereas no loosening occurred in type 2 hips. There was consolidation of the hydroxyapatite layer in 33 hips (66%). Loosening was detected in nine of 29 hips (31%) without cement and in one of 20 hips (5%) with cement (p = 0.03, Fisher's exact probability test). The linear wear and annual wear rate did not correlate with loosening. These results suggest that the long-term results of hydroxyapatite grafting with cement for type 2 and 3A hips are encouraging. PMID:20798437

Sakai, T; Ohzono, K; Nishii, T; Miki, H; Takao, M; Sugano, N



Use of interactive lecture demonstrations: A ten year study  

NSDL National Science Digital Library

The widely held constructivist view of learning advocates student engagement via interactivity. Within the physics education research community, several specific interactive strategies have been developed to enhance conceptual understanding. One such strategy, the Interactive Lecture Demonstration (ILD) is designed for large lecture classes and, if measured using specific conceptual surveys, is purported to provide learning gains of up to 80%. This paper reports on learning gains for two different Projects over ten years. In Project 1, the ILDs were implemented from 1999 to 2001 with students who had successfully completed senior high school physics. The learning gains for students not exposed to the ILDs were in the range 13% to 16% while those for students exposed to the ILDs was 31% to 50%. In Project 2, the ILDs were implemented from 2007 to 2009 with students who had not studied senior high school physics. Since the use of ILDs in Project 1 had produced positive results, ethical considerations dictated that all students be exposed to ILDs. The learning gains were from 28% to 42%. On the one hand it is pleasing to note that there is an increase in learning gains, yet on the other, we note that the gains are nowhere near the claimed 80%. This paper also reports on teacher experiences of using the ILDs, in Project 2.

Sharma, Manjula D.; Johnston, Ian D.; Johnston, Helen; Varvell, Kevin; Robertson, Gordon; Hopkins, Andrew



Quality of Life in the Late Follow-Up of Ulcerative Colitis Patients Submitted to Restorative Proctocolectomy with Sphincter Preservation Over Ten Years Ago  

PubMed Central

OBJECTIVE To evaluate, by means of the Inflammatory Bowel Disease Questionnaire (IBDQ), the quality of life of ulcerative colitis patients submitted to proctocolectomy with sphincter preservation using J-pouch reconstruction over ten years ago. METHODS The study consisted of 36 patients interviewed using the Inflammatory Bowel Disease Questionnaire. The score scale, resulting from the addition of each answer, ranged from 32 to 224, where the highest score indicates the best quality of life. The chi square test was used to verify the existence of meaningful differences between the results of the questionnaire and age, and gender proportion. For each section, as well as for all of them combined, the Kruskal-Wallis test was used to verify if there were differences in the Inflammatory Bowel Disease Questionnaire scores among the groups in relation to the proportions. RESULTS After applying the Inflammatory Bowel Disease Questionnaire, it was determined that quality of life was considered excellent for 9 (25%), good for 11 (30.6%), regular for 13 (36.1%), and bad for 3 (8.3%) patients. In our study, we determined that 85% of the patients were pleased with and thankful for the surgery that they underwent. CONCLUSION We can conclude that the possibility of sphincter preservation should always be taken into account, since patients remain clinically stable and have a high quality of life even after long periods.

Meyer, Alberto Luiz Monteiro; Teixeira, Magaly Gemeo; de Almeida, Maristela Gomes; Kiss, Desiderio Roberto; Nahas, Sergio Carlos; Cecconello, Ivan



Follow-up Study of 1988 Graduates.  

ERIC Educational Resources Information Center

This follow-up study of 1988 graduates of Detroit (Michigan) public high schools examines the status of graduates one year following graduation. Information was gathered from a survey and correlated with demographic and achievement information from student records. Findings must be interpreted in light of a 24 percent response rate to the survey,…

Leddick, Linda; Stavros, Denny


Problems in Follow-Up Studies  

ERIC Educational Resources Information Center

Recent regulations concerning consent procedures and protection of privacy fall most severely on follow-up studies of children. Compliance with current regulations on subjects' rights sometimes seems potentially more harmful to the subjects than is the research itself. (Author/AM)

Robins, Lee N.



Temperament and character in eating disorders: ten years of studies.  


In recent years a number of studies of personality have been performed in subjects with Eating Disorders (EDs) to investigate the clinical differences between controls and ED patients and among EDs subtypes, and its role in the development and course of symptoms. The Tridimensional Personality Questionnaire (TPQ) and the Temperament and Character Inventory (TCI) have been widely used at this purpose, allowing the description of specific temperament and character profiles for EDs. High Harm Avoidance (HA) and low Self-Directedness (SD) are shared by all EDs. Slight differences on some facets have been found among ED subgroups. Nevertheless, HA is influenced by mood and both high HA and low SD are personality traits shared by many mental disorders, whose specificity is rather low. Restrictor anorectics are characterized by high Persistence (P) and a relatively higher SD, and bulimics by higher Novelty Seeking (NS) and the lowest SD, while binge/purging and purging anorectics share some traits with anorexia and some with bulimia. Though current data justify the discrimination among anorexia subtypes, they are not in contrast with the thesis of a continuum in ED personality traits. Since some personality traits display a prognostic value with regard to therapy and clinical outcome, further studies are needed on treatments and prognostic factors in EDs. Moreover, studies attempting to define the neurobiological and genetic correlates of temperament should be supported by clinical pharmacological trials. PMID:15330074

Fassino, S; Amianto, F; Gramaglia, C; Facchini, F; Abbate Daga, G



Ten years of Developing International Volcanology Graduate Study Programs  

NASA Astrophysics Data System (ADS)

In 2000 I reported at this symposium about multi-institutional graduate field trips to IAVCEI events, such as the Bali meeting and its importance in building international collegiality and awareness among the volcanology doctoral students. NSF was an enthusiastic supporter of these field sessions and this support has continued through the highly successful Pucon and Reykjavik sessions. International volcanology graduate program development began with several exchange programs. EHaz was a highly successful program (McGill, Simon Fraser, Michigan Tech, Buffalo, UNAM and Universidad de Colima) funded by the Department of Education (FIPSE) that moved students across North America where dozens of graduate students spent semesters of their study abroad and shared annual field trips and online student led graduate seminar classes. Michigan Tech’s volcanology graduate program started a Masters International program that combined Peace Corps service with hazards mitigation graduate study and students were placed by Peace Corps in countries with prominent natural hazards. The new program funded 2 year residences in foreign environments, principally in Pacific Latin America. NSF strongly supported this program from its inception, and eventually it gained NSF PIRE support. Dozens of students have initiated the 3 year program (15 completed) to date. A similar PIRE developed at UAF with a link to volcanology in the Russian Far East. One gain is the development of many socially-conscious research selections. Beginning this year transatlantic dual degree masters programs in volcanology are being offered by a consortium of US and European volcanology programs (Michigan Tech, Buffalo, Clermont Ferrand and University of Milan Bicocca), again aided by FIPSE funding. Students have dual advisors on both sides of the Atlantic and spend about half of their two year programs in Europe and half in US. Faculty also travel in the program and the four campuses are increasingly linked by coursework and research networks. Because the international developments of volcanology programs address the need for more robust coursework and research choices for students than are possible on one campus, and because they lead to a diverse network of professional contacts , we think the next decade will bring many more multi-university volcanology programs linked to field sites all over the world.

Rose, W. I.



Obstructing colonic cancer: Failure and survival patterns over a ten-year follow-up after one-stage curative surgery  

Microsoft Academic Search

BACKGROUND: Large-bowel cancers that present as obstructing lesions have a poor prognosis. However, little is known of the reasons for the dismal survival and of failure patterns after potentially curative treatment. METHOD: An observational study and multivariate analysis were conducted to identify determinants of survival and to compare recurrence patterns between obstructing and nonobstructing tumors after primary resection and anastomosis

Paolo G. Setti Carraro; Marco Segala; Bruno M. Cesana; Giorgio Tiberio



Ten-year follow-up of a prospective trial for the targeted therapy of gastric cancer with the human monoclonal antibody PAT-SC1.  


The fully human monoclonal antibody PAT-SC1 is specific for an isoform of CD55 (decay-accelerating factor) designated CD55PAT-SC1. This antigen is expressed in the majority (80%) of gastric cancers (GCs), and the antibody induces tumour cell-specific apoptosis in vitro as well as in vivo. PAT-SC1, therefore, has been deemed promising as a therapeutic agent. Here, we describe the results of an academic clinical study performed in a neoadjuvant setting with resectable GC patients. Patients undergoing treatment for GC between 1997 and 2001 were tested for CD55PAT-SC1 expression. Fifty-one resectable patients that tested positively received a single administration of 20 mg PAT-SC1 48 h prior to surgery. They underwent standard surgery with either subtotal or total gastrectomy with bursectomy, omentectomy and a modified D2-lymphadenectomy, aimed at R0 resection. Primary endpoints of the present study were to evaluate side-effects of the PAT-SC1 antibody treatment and to evaluate histopathological effects such as tumour regression and induction of apoptosis. Long-term survival was a secondary endpoint. Administration of PAT-SC1 appeared safe with only reversible side-effects according to WHO grade I and II. Despite the low?dose of the antibody, 81.6% of the patients showed signs of increased apoptosis within the primary tumour and 60% showed signs of tumour cell regression. Comparison of the 10-year survival rates of the R0-resected CD55PAT-SC1-positive patients treated with the PAT-SC1 antibody with a historical collective of R0-resected CD55PAT-SC1-positive patients not treated with PAT-SC1 indicated a survival benefit in the treated patients. Furthermore, comparison of the patient survival of CD55PAT?SC1-positive vs. CD55PAT-SC1-negative groups suggested that CD55PAT-SC1 antigen expression is an independent predictor of poor survival in a Cox regression analysis. Antibody PAT-SC1 may be a useful additive therapeutic agent in the treatment of patients with CD55PAT-SC1-expressing GCs. In combination with radical standard surgery, PAT-SC1 given as an adjuvant or neoadjuvant immunotherapeutic agent induces apoptosis in tumour cells which may improve survival of these patients. Because of the human origin and its specific binding to the CD55PAT-SC1 antigen, PAT-SC1 was well tolerated in this trial. PMID:24452482

Hensel, Frank; Timmermann, Wolfgang; von Rahden, Burkhard H A; Rosenwald, Andreas; Brändlein, Stephanie; Illert, Bertram



Parent training, home environment, and early childhood development: A long?term follow?up study  

Microsoft Academic Search

Families and children who participated in a primary prevention experiment called Home Oriented Preschool Education (HOPE) were assessed during a follow?up study approximately ten years following the experiment. Home environment and social class were assessed for families, and children's ability and achievement test scores and grade point averages were obtained from school records. Home environment was shown to be only

Edward E. Gotts



Cooperative Thyrotoxicosis Therapy Follow-Up Study.  

National Technical Information Service (NTIS)

The thyrotoxicosis study was initiated in 1961 to test for an increase in the incidence of leukemia in hyperthyroid patients treated with iodine-131. Twenty-two study centers representing twenty-six medical institutions submitted records on 36,000 patient...

L. Mills



Follow-up study of alcoholic hallucinosis  

PubMed Central

Alcoholic hallucinosis is a pathological mental state characterized by an acute onset of predominant auditory hallucinations that occur either during or after a period of heavy alcohol consumption. In this study, 52 patients with a diagnosis of Psychotic disorder predominantly hallucinatory associated with alcohol use (F 10.52) were evaluated after a period of three years. Past history of withdrawal hallucinations was associated with alcoholic hallucinosis The study has found a wide spectrum of outcome confirming the earlier observations that alcoholic hallucinosis is a heterogeneous disorder.

Perme, Bojir; Vijaysagar, Kommu John; Chandrasekharan, R.



Academic Self-concept and Educational Attainment Level: A Ten-year Longitudinal Study  

Microsoft Academic Search

The purpose of this study was to test children's academic self-concept, family socioeconomic status, family structure (single parent vs. two parent family) and academic achievement in elementary school as predictors of children's educational attainment level in young adulthood within a ten-year longitudinal design. Participants (254 girls, 211 boys) were three cohorts of students in Grades 3, 4, and 5 from

Frédéric Guay; Simon Larose; Michel Boivin



“Cold calling” in psychiatric follow up studies: is it justified?  

Microsoft Academic Search

Background: The ethics of cold calling—visiting subjects at home without prior appointment agreed—in follow up research studies has received little attention although it is perceived to be quite common. We examined the ethical implications of cold calling in a study of subjects with defined neurotic disorders followed up 12 years after initial assessment carried out to determine outcome in terms

P Tyrer; H Seivewright; B Ferguson; T Johnson



Outcome of opening wedge high tibial osteotomy augmented with a Biosorb® wedge and fixed with a plate and screws in 124 patients with a mean of ten years follow-up.  


The objective of this work was firstly to evaluate the long-term results of medial opening wedge high tibial osteotomy (HTO) and secondly to evaluate the tolerance and integration of a Biosorb® wedge (? Tricalcium Phosphate, SBM Company, Lourdes, France). The series consisted of 124 knees in 110 patients, 74 men and 36 women, with mean age of 53.23±10.68 years (range 32-74) and treated between June 1995 and November 2000 for medial compartment knee osteoarthritis by the senior author. The mean preoperative Lysholm and Tegner functional score was 65.44±13.32 (range 27-80) and the preoperative HKA angle was 172.51°±3.8° (range 162-179°). According to the modified Ahlbäck classification there were 27 stage I, 42 stage II, 44 stage III and 11 stage IV knees. All patients were reviewed clinically and radiologically with a mean follow-up of 10.39±1.98 years (range 8-14 years). Immediate postoperative complications consisted of nine undisplaced lateral tibial plateau fractures of no clinical significance, two deep vein thromboses and three pulmonary emboli which resolved with appropriate treatment. At a later stage, there were seven delayed unions without development of pseudarthrosis, and three screw breakages when the AO T-plate was used, leading to a secondary angulation in one case, requiring revision by femoral osteotomy. Postoperative mean weightbearing HKA angle was 182°±1.8° (range 178-186°) and 73.4% of axes were 184°±2°. Fifteen knees (12.1%) underwent total knee arthroplasty (TKA) after a mean delay of 8.87±3.04 years and were excluded from the final analysis. Concerning the long-term results (n?=?107 knees), the mean Lysholm-Tegner score was 88±12.7 points (51-100) and the KOOS score was 86±14.6 points (25-100) with 94 patients satisfied or very satisfied (87.85%). In terms of the HTO survivorship curve, with failure consisting of revision to TKA or another operation, survival was 88.8% at five years and 74% at ten years. Concerning Biosorb®, this was completely integrated in 100% of cases and there was complete resorption in 12.1% of cases and greater than 50% resorption in 52.3% of cases. PMID:20668849

Saragaglia, Dominique; Blaysat, Marc; Inman, Dominic; Mercier, Numa



Fistula-in-ano: A ten-year follow-up study of horseshoe-abscess fistula-in-ano  

Microsoft Academic Search

Summary  A preliminary report in 19654 described a conservative surgical procedure for the management of acute and chronic horseshoe anal fistulas. The operation\\u000a has been used exclusively at the Ochsner Clinic for this problem since 1963. Forty-one patients were treated from 1963 to\\u000a 1973.\\u000a \\u000a The paper reviews the pathology of acute and chronic horseshoe anal fistulas and describes the surgical procedure

Patrick H. Hanley; John E. Ray; E. Earl Pennington; Oscar M. Grablowsky



Urodynamic profile in myelopathies: A follow-up study  

PubMed Central

Aims: To study the significance of filling cystometry in assessment and management of neurogenic bladder in myelopathies and correlate neurological recovery and bladder management in the follow up. Study Design: Retrospective analysis of reports of filling cystometry in patients with traumatic and non-traumatic myelopathy. Setting: Neuro-rehabilitation unit of a tertiary care university hospital. Methods: The study was carried out between September 2005 and June 2006 and included all subjects with myelopathy who underwent filling cystometry. ASIA impairment scale was used to assess neurological status during admission as well as in the follow up. Bladder management was advised based on the cystometric findings. Neurological recovery and mode of bladder management were correlated during the follow up after a minimum of 6 months. Results: Fifty-two subjects (38 males, 14 females), mean age 33.26 ± 14.66 years (10–80) underwent filling cystometry. Twenty patients had cervical, 24 had thoracic and 8 had lumbar myelopathy. Cystometric findings were overactive detrusor observed in 43 patients, (21 had detrusor sphincter dyssynergia (DSD), 22 without DSD) and areflexic/underactive detrusor in 9. Post-void residual (>15% of voided urine) was significant in 27 patients. Twenty-three patients (44%) reported for follow up (16 males, 7 females) after a mean duration of 9.04 ± 2.44 months (6–15 months). Neurological recovery was seen in 61% cases, while 1 patient showed deterioration. Only 26% patients reported change in bladder management during follow up. Correlation between neurological recovery and bladder management was found to be insignificant (P > 0.05) using spearman correlation co-efficient. Conclusions: Filling cystometry is valuable for assessment and management of neurogenic bladder after myelopathy. No significant relationship was observed between neurological recovery and neurogenic bladder management in the follow up in the present study.

Gupta, Anupam; Taly, Arun B.; Srivastava, Abhishek; Thyloth, Murali



Follow-Up Study of 1994 Dental Hygiene Graduates.  

ERIC Educational Resources Information Center

In an effort to evaluate the effectiveness of its dental hygiene program, William Rainey Harper College (WRHC), in Illinois, conducted a follow-up study of program graduates from 1994. Surveys were mailed to all 30 1994 dental hygiene associate degree graduates, receiving responses from 77% (n=23). Study findings included the following: (1) all…

Holt, Marianne; Lucas, John A.


Flouride. Ten-year prospective study of deciduous and permanent dentition.  


A ten-year longitudinal prospective study compared the effect of fluoride on dentition of 1,500 children from infancy through age 10 years. In Kalamazoo, Mich, and Oneida, NY, parallel groups were given a fluoride-vitamin supplement from infancy and from age 4 and compared with fluoridated water and control groups. Incidence of new caries activity in both deciduous and permanent teeth was measured by mean number of new decayed and filled teeth, as well as percentage of children with no caries throughout the periods studied. Prevalence of caries was also studied in six-year molars. The results indicate a consistent (and, for selected groups, a statistically significant) diminution in caries activity for both deciduous and permanent teeth for groups ranked from greatest retardation of caries to least: infant fluoride group, water fluoride group, age 4 fluoride group, and controls. PMID:1096595

Margolis, F J; Reames, H R; Freshman, E; MaCauley, C D; Mehaffey, H



Follow-up Study of 1989 Graduates. Detroit Public Schools.  

ERIC Educational Resources Information Center

This study of 1989 graduates represents the second year that the Detroit (Michigan) Public School system has conducted a follow-up survey of public high school graduates to establish their occupational status at about 16 months after graduation, collect their perceptions of their high school experiences, and record their postsecondary educational…

Stavros, Denny


Preschool Language Intervention: A Follow-Up Study.  

ERIC Educational Resources Information Center

A follow-up study at a mean age of 8.3 years of 38 children who had attended a preschool language unit found that 84 percent were within the mainstream of education, but a slight continuing language difficulty was apparent on standardized tests. Results suggested preschool language intervention helped to prevent later educational failure. (DB)

Shelagh, Urwin; And Others



1982-83 Graduate Follow-Up Study.  

ERIC Educational Resources Information Center

In fall 1983, a follow-up study was conducted of all 1982-83 graduates of St. Louis Community College at Forest Park. Questionnaires were sent to 610 graduates of transfer programs and 1- and 2-year career programs soliciting information on graduates' current location, employment status, postsecondary educational experiences, reactions to the…

Nienkamp, Roger L.


A Follow-Up Study of Former Student Health Advocates  

ERIC Educational Resources Information Center

Student health advocates (SHAs) are high school students who, under the supervision of the school nurse, provide health education and health promotion activities to other students via a peer education model. This 3-year follow-up study explored how the SHA experience influences career choice and attitudes of the participants. It also examined what…

Streng, Nancy J.



Ten-Year Objective Physical Activity Tracking: Iowa Bone Development Study  

PubMed Central

Purpose To examine tracking of physical activity (PA) over a ten-year period and investigate whether sex differences in PA trajectories are altered after aligning by maturity instead of age. Methods The Iowa Bone Development Study collected accelerometer data on a cohort of 140 girls and 128 boys at ages 5, 9, 11, 13, and 15 yr. Logistic regression determined the odds ratio of being in lowest PA tertile at 15 yr if in lowest tertile at age 5. Spearman correlation coefficients examined PA tracking from age 5 to 15. Using additional Iowa Bone Development participants at ages 9, 11, 13, and 15 (N=482, 457, 416, and 316, respectively), we examined the stability of PA for chronological and biological age in two-year intervals surrounding peak height velocity (PHV) age. Year from PHV was estimated using Mirwald prediction equation. Results Girls had significant ten-year correlations (r=0.27); boys did not. Girls, not boys, were more likely to be in the lowest tertile for PA at age 15 if in the lowest tertile at age 5 (OR=3.1 MVPA; 95% CI=1.4, 6.9; OR=2.8 Vigorous PA; 95% CI=1.2, 6.1). Girls’ two-year intervals for PA showed moderate associations (r=0.31–0.56) when aligned chronologically, but were moderate to high (r=0.41–0.63) when aligned biologically. Boys’ associations were low to moderate (r=0.26–0.56) chronologically. When aligned biologically, the associations were low for the ?1 to 1 yr interval (1 yr prior to 1 yr post-PHV), but moderate to high for the ?2 to 0 yr and 0 to 2 yr intervals (r=0.50–0.61). Conclusion Physical activity tracking from childhood to adolescence is stronger in girls than boys. Intervention programs targeting boys should focus on time surrounding puberty in boys where activity patterns change.

Francis, Shelby L.; Morrissey, Joanna L.; Letuchy, Elena M.; Levy, Steven M.; Janz, Kathleen F.



Less wear with aluminium-oxide heads than cobalt-chrome heads with ultra high molecular weight cemented polyethylene cups: A ten-year follow-up with radiostereometry  

Microsoft Academic Search

Purpose  Wear is a major contributor to osteolysis and aseptic loosening of total hip replacements (THR). Both alumina (Al2O3) and cobalt-chrome (CoCr) femoral heads are commonly used. We investigated wear comparing alumina heads to cobalt-chrome\\u000a heads against conventional cemented polyethylene (PE) cups for up to ten years.\\u000a \\u000a \\u000a \\u000a \\u000a Methods  Linear wear was measured with radiostereometry (RSA). Our material was derived from two prospective randomised

Jon Dahl; Per Söderlund; Bo Nivbrant; Lars Nordsletten; Stephan M. Röhrl


Myotomy: Follow-up study of 50 patients  

Microsoft Academic Search

Laparoscopic myotomy has become the standard treatment for definitive management of achalasia. This study was undertaken to\\u000a assess the long-term results of the procedure. Perioperative data, including a symptom score questionnaire, were collected\\u000a prospectively on all patients undergoing laparoscopic myotomy. The same questionnaire was readministered by phone to patients\\u000a with follow-up greater than 3.75 years. The long-term success of myotomy

Barry R. Berch; R. Dean Nava; Alfonso Torquati; Kenneth W. Sharp; William O. Richards



Analyzing the Study of Using Acupuncture in Delivery in the Past Ten Years in China  

PubMed Central

The use of acupuncture in inducing delivery has a long history in China. With progress over time, it has been applied in many aspects. For further study of acupuncture in delivery, this paper analyzed the papers using acupuncture in delivery in the past ten years in mainland China. 87 literatures were picked out by searching relevant electronic databases and bibliographies of relevant journals. The analysis showed randomized controlled trials that were the major type of research, while preclinical researches and literature reviews only account for around ten percent, respectively. Clinical researches indicated that acupuncture can relieve labor pain, promote maternal uterine contraction, shorten birth process, and treat postpartum disorders. Preclinical researches found that acupuncture can adjust certain hormones and improve uterus contraction of late-stage pregnant rats. However, due to lack of large multicenter randomized controlled clinical trials, standardized evaluations of clinical effects in clinical researches and detailed mechanism study in preclinical researches and unequivocal conclusions about the effectiveness, efficacy, and mechanisms of acupuncture in this field cannot be obtained from those researches yet. Further clinical and preclinical studies about the use of acupuncture in delivery with improved methodology is still needed.

Chen, Yingru; Zhang, Xuekai; Fang, Yigong; Yang, Jinsheng



Colon Cancer Survival With Herbal Medicine and Vitamins Combined With Standard Therapy in a Whole-Systems Approach: Ten-Year Follow-up Data Analyzed With Marginal Structural Models and Propensity Score Methods  

Microsoft Academic Search

Although localized colon cancer is often successfully treated with surgery, advanced disease requires aggressive systemic therapy that has lower effectiveness. Approximately 30% to 75% of patients with colon cancer use complementary and alternative medicine (CAM), but there is limited formal evidence of survival efficacy. In a consecutive case series with 10-year follow-up of all colon cancer patients (n = 193)

Michael McCulloch; Michael Broffman; Mark van der Laan; Alan Hubbard; Lawrence Kushi; Donald I. Abrams; Jin Gao; John M. Colford




EPA Science Inventory

The Follow-up questionnaire data set contains information concerning the activities within the household during the sampling week. The information is from 402 follow-up questionnaires for 80 households across 6 cycles. The Follow-up Questionnaire specifically addressed the time ...


Colon Cancer Survival With Herbal Medicine and Vitamins Combined With Standard Therapy in a Whole-Systems Approach: Ten-Year Follow-up Data Analyzed With Marginal Structural Models and Propensity Score Methods  

PubMed Central

Although localized colon cancer is often successfully treated with surgery, advanced disease requires aggressive systemic therapy that has lower effectiveness. Approximately 30% to 75% of patients with colon cancer use complementary and alternative medicine (CAM), but there is limited formal evidence of survival efficacy. In a consecutive case series with 10-year follow-up of all colon cancer patients (n = 193) presenting at a San Francisco Bay-Area center for Chinese medicine (Pine Street Clinic, San Anselmo, CA), the authors compared survival in patients choosing short-term treatment lasting the duration of chemotherapy/radiotherapy with those continuing long-term. To put these data into the context of treatment responses seen in conventional medical practice, they also compared survival with Pan-Asian medicine + vitamins (PAM+V) with that of concurrent external controls from Kaiser Permanente Northern California and California Cancer Registries. Kaplan-Meier, traditional Cox regression, and more modern methods were used for causal inference—namely, propensity score and marginal structural models (MSMs), which have not been used before in studies of cancer survival and Chinese herbal medicine. PAM+V combined with conventional therapy, compared with conventional therapy alone, reduced the risk of death in stage I by 95%, stage II by 64%, stage III by 29%, and stage IV by 75%. There was no significant difference between short-term and long-term PAM+V. Combining PAM+V with conventional therapy improved survival, compared with conventional therapy alone, suggesting that prospective trials combining PAM+V with conventional therapy are justified.

McCulloch, Michael; Broffman, Michael; van der Laan, Mark; Hubbard, Alan; Kushi, Lawrence; Abrams, Donald I.; Gao, Jin; Colford, John M.



Education On Prehospital Pain Management: A Follow-Up Study  

PubMed Central

Introduction: The most common reason patients seek medical attention is pain. However, there may be significant delays in initiating prehospital pain therapy. In a 2001 quality improvement (QI) study, we demonstrated improvement in paramedic knowledge, perceptions, and management of pain. This follow-up study examines the impact of this QI program, repeated educational intervention (EI), and effectiveness of a new pain management standard operating procedure. Methods: 176 paramedics from 10 urban and suburban fire departments and two private ambulance services participated in a 3-hour EI. A survey was performed prior to the EI and repeated one month after the EI. We reviewed emergency medical services (EMS) runs with pain complaints prior to the EI and one month after the EI. Follow-up results were compared to our prior study. We performed data analysis using descriptive statistics and chi-square tests. Results: The authors reviewed 352 surveys and 438 EMS runs with pain complaints. Using the same survey questions, even before the EI, 2007 paramedics demonstrated significant improvement in the knowledge (18.2%; 95% CI 8.9%, 27.9%), perceptions (9.2%; 95% CI 6.5%, 11.9%), and management of pain (13.8%; 95% CI 11.3%, 16.2%) compared to 2001. Following EI in 2007, there were no significant improvements in the baseline knowledge (0%; 95% CI 5.3%, 5.3%) but significant improvements in the perceptions of pain principles (6.4%; 95% CI 3.9%, 9.0%) and the management of pain (14.7%; 95% CI 11.4%, 18.0%). Conclusion: In this follow up study, paramedics’ baseline knowledge, perceptions, and management of pain have all improved from 6 years ago. Following a repeat educational intervention, paramedics further improved their field management of pain suggesting paramedics will still benefit from both initial and also ongoing continuing education on the topic of pain management.

French, Scott C.; Chan, Shu B.; Ramaker, Jill



A Test of Gottfredson's Theory Using a Ten-Year Longitudinal Study  

Microsoft Academic Search

Occupational aspirations of a longitudinal sample of students were examined over a ten-year time period, from second to twelfth grade. Hypotheses from Gottfredson's theory of career development (1981, 1996) and from social learning theory (Lent, Brown & Hackett, 1994) were examined. The social value of children's occupational aspirations increased into the early high school years and started to fall by

Andrew A. Helwig



Ten-year follow-up after autologous stem cell transplantation of a patient with immunoglobulin light-chain (AL) amyloidosis with deposits in the heart, liver and gastrointestinal tract  

PubMed Central

The prognosis in amyloid light chain (AL)-amyloidosis and multiorgan involvement is poor, with a high-treatment-related mortality after high-dose melphalan and autologous stem cell transplantation (HDM/SCT). Some patients, however, might benefit from the therapy. We report a case of cardiac AL-amyloidosis with multiorgan involvement where the progressive cardiomyopathy was halted after successful treatment with HDM/SCT in 2001. The patient is in an excellent cardiac condition with a good quality of life, receiving treatment with angiotensinogen receptor blockers and a flexible diuretics regimen at follow-up after 10 years.

Mejhert, Marit; Hast, Robert; Sandstedt, Benngt; Janczewska, Izabella



Ten year longitudinal study of neuropsychological functioning subsequent to a first episode of schizophrenia.  


We previously reported relative stability in neuropsychological functions over a 4- to 5-year period after the onset of a first episode of schizophrenia, with patients demonstrating less improvement than controls on some functions [Hoff, A.L., Sakuma, M., Wieneke, M., Horon, R., Kushner, M., DeLisi, L.E., 1999. A longitudinal follow-up study of neuropsychological functioning subsequent to a first-episode of schizophrenia. American Journal of Psychiatry 156, 1336-1341.]. The current study was conducted to extend follow-up evaluations through 10 years of illness to determine whether neuropsychological functions remain stable or deteriorate over a longer time period. Twenty-one first episode patients and 8 controls were re-evaluated 10 years after an initial evaluation on neuropsychological and clinical measures. Repeated measures analyses demonstrated no differences between patients and controls in degree of change over this time period nor was change in symptoms reliably associated with improvement or deterioration in cognitive abilities. However, baseline level of cognitive functioning was correlated with the degree of change. Thus, when the baseline level of functioning was controlled for in the analyses, less or lack of improvement was seen in the patients compared with controls in verbal intellectual functioning, delayed verbal and nonverbal recall, and cognitive inhibition (Stroop Color Word Test). In no test did patients deteriorate significantly more than controls. We conclude that most first episode patients have had considerable cognitive decline by the time of their first hospitalization and that it remains relatively stable through at least 10 years of illness. Most cognitive change takes place early in this illness, prior to the first hospitalization, but its exact timing still remains unknown. PMID:15964177

Hoff, Anne L; Svetina, Christine; Shields, Gail; Stewart, John; DeLisi, Lynn E




EPA Science Inventory

The Follow-up Questionnaire data set provides information concerning the activities within the household during the sampling week. The information is from 774 Follow-up Questionnaires for 320 households. Medication and supplemental dietary information is provided. The Follow-u...


Campylobacter antimicrobial resistance in Peru: a ten-year observational study  

PubMed Central

Background Campylobacter jejuni and Campylobacter coli are food-borne pathogens of great importance and feature prominently in the etiology of developing world enteritis and travellers’ diarrhoea. Increasing antimicrobial resistant Campylobacter prevalence has been described globally, yet data from Peru is limited. Our objective was to describe the prevalence trends of fluoroquinolone and macrolide-resistant C. jejuni and C. coli stool isolates from three regions in Peru over a ten-year period. Methods Surveillance for enteric pathogens was conducted in Lima, Iquitos and Cusco between 2001 and 2010. Campylobacter stool isolates were tested for susceptibilities to ciprofloxacin, azithromycin and erythromycin. Susceptibilities were reviewed for 4652 isolates from Lima ( n?=?3419), Iquitos ( n?=?625) and Cusco ( n?=?608). Results Comparing the study periods of 2001-2005 and 2006-2010, prevalence of ciprofloxacin-resistant C. jejuni isolates rose in the study areas of Lima (73.1% to 89.8%, p?studies to explore the relationship between increasing antimicrobial resistance and agricultural or human antibiotic use may be valuable.



Hydrotherapy after total knee arthroplasty. A follow-up study.  


The study evaluated the subjective functional outcome following total knee arthroplasty (TKA) in participants who underwent hydrotherapy (HT) six months after discharge from a rehabilitation unit. A total of 70 subjects, 12 of which were lost at follow-up, were randomly assigned to either a conventional gym treatment (N=30) or HT (N=28). A prospective design was performed. Participants were interviewed with Western-Ontario McMasters Universities Osteoarthritis Index (WOMAC) at admission, at discharge and six months later. Kruskal-Wallis and Wilcoxon tests were applied for statistical analysis. Both groups improved. The WOMAC subscales, namely pain, stiffness and function, were all positively affected. Statistical analysis indicates that scores on all subscales were significantly lower for the HT group. The benefits gained by the time of discharge were still found after six months. HT is recommended after TKA in a geriatric population. PMID:19735951

Giaquinto, S; Ciotola, E; Dall'Armi, V; Margutti, F



A follow-up study of 69 discharged SARS patients.  


Sixty-nine patients with severe acute respiratory syndrome (SARS) discharged from Guangdong Provincial TCM Hospital were followed up from January to April 2003 during which the patients were asked to fill the questionnaire form and at the same time received blood routine examination, hepatic, renal, pulmonary and immune function tests, and spiral computerized tomography (CT) of the chest, color B-ultrasonography of the heart with the collected data treated by descriptive analysis and deductive analysis. The results showed that in the 69 followed-up patients, impairment of the hepatic function was found in 5 cases, hypoimmune state in 18, impediment of ventilation in the distal air passages with normal major air passages in 15, increased residual volume in 40, mild disturbance of pulmonary diffusion function in 14, incomplete absorption of inflammatory exudates, focal or multiple interstitial lesions, pulmonary interstitial fibrosis and pleural adhesion in 24; increased resistance or mild systolic hypertension in the pulmonary circulation, and segmental ischemia of the left myocardium in 34; and decreased visual acuity in 2. According to TCM differentiation 24 cases belonged to the type of deficiency of both qi and yin, 8 deficiency of both the heart and spleen, 37 depression of the liver and deficiency of the spleen, 18 intermingling with damp-heat, and 7 intermingling with stagnant blood. Some patients still had psychological problems. The study indicates that though clinically cured and discharged from hospital, some SARS patients have functional impairment of the heart, lung and liver, hypoimmune state as well as psychological problems, and need to be treated accordingly for a complete recovery. A rationale for suggested TCM treatment is expounded. PMID:14535196

Han, Yun; Geng, Hui; Feng, Weibin; Tang, Xiangjiang; Ou, Aihua; Lao, Yingrong; Xu, Yinji; Lin, Hao; Liu, Hui; Li, Yongwen




PubMed Central

SUMMARY The paper describes the usefulness of a treatment method for writer's cramp. Three cases of writer's cramp are described and in all the three, the response to treatment has been good after treatment and on follow up.

John, Jacob; Roy, Ashok; Saidu, Mohammed; Joseph, George; Verghese, Abraham



Ten-year fatal and non-fatal myocardial infarction incidence in elderly populations in Spain: the EPICARDIAN cohort study  

Microsoft Academic Search

BACKGROUND: In Spain, more than 85% of coronary heart disease deaths occur in adults older than 65 years. However, coronary heart disease incidence and mortality in the Spanish elderly have been poorly described. The aim of this study is to estimate the ten-year incidence and mortality rates of myocardial infarction in a population-based large cohort of Spanish elders. METHODS: A

Rafael Gabriel; Margarita Alonso; Blanca Reviriego; Javier Muñiz; Saturio Vega; Isidro López; Blanca Novella; Carmen Suárez; Francisco Rodríguez-Salvanés



COPD and microalbuminuria: a 12-year follow-up study.  


Chronic obstructive pulmonary disease (COPD), low lung function independent of diagnosis and markers of inflammation are all associated with increased morbidity and mortality. Microalbuminuria, reflecting endothelial dysfunction, could be a relevant inflammatory marker of potential systemic effects of COPD. We hypothesised that there was a positive association between microalbuminuria and mortality in individuals with COPD. We conducted a 12-year follow-up study of 3129 participants in the second survey of the Nord-Trøndelag Health Study (HUNT), Norway. At baseline, albuminuria was analysed in three urine samples and spirometry was performed. Among the participants, 136 had COPD and microalbuminuria, defined as a urinary albumin/creatinine ratio between 2.5 and 30.0 mg·mmol(-1). The main outcome measures were hazard ratio of all-cause mortality according to microalbuminuria. Compared to those with COPD without microalbuminuria, the adjusted hazard ratio for all-cause mortality in those with COPD and microalbuminuria was 1.54, 95% CI 1.16-2.04. This result was similar after excluding cardiovascular disease at baseline. Classifying COPD severity by Global Initiative for Chronic Obstructive Lung Disease, there was a positive association trend with increasing severity stages. Microalbuminuria is associated with all-cause mortality in individuals with COPD and could be a relevant tool in identification of patients with poor prognosis. PMID:24435009

Romundstad, Solfrid; Naustdal, Thor; Romundstad, Pål Richard; Sorger, Hanne; Langhammer, Arnulf



Acute posterior multifocal placoid pigment epitheliopathy. A follow up study.  


Thirteen patients with acute posterior multifocal placoid pigment epitheliopathy (APMPPE) were followed up for a period of from 1 to 20 years (median 5 years 8 months). Five patients developed lesions in the previously unaffected fellow eye during the follow up period. In three patients the condition progressed during a prolonged period without interruption. Widespread severe choroidal atrophy was a late feature in a number of cases. In seven out of thirteen cases, visual acuity remained defective (6/18 or less) in one or both eyes. The prevailing opinion that that APMPPE is self limiting may be incorrect. PMID:6591590

Damato, B E; Nanjiani, M; Foulds, W S



Quality of life after volar locked plating: a 10-year follow-up study of patients with intra-articular distal radius fractures  

PubMed Central

Background This study aimed to present functional results and patient’s health related quality of life (HRQOL) data ten years after volar locked plate fixation (VPF) of unstable intra-articular distal radial fractures (DRF). Methods Thirty-nine patients with a mean age of sixty-one years were operatively treated with VPF after intra-articular distal radial fractures. They were evaluated two, six, and ten years postoperatively according to the Gartland and Werley score. For subjective evaluation the Short Form 36 (SF-36) and the Disability of Arm, Shoulder and Hand (DASH) questionnaires were adopted. Results Overall, wrist function did not differ significantly two, six and ten years after the operation. Over 90% patients achieved “good” or “excellent” results ten years after surgery according to the Gartland and Werley score. Ten years postoperatively the results of the SF 36 did not differ significantly from the two- and six-year follow-up. Overall findings from the SF-36 did not differ significantly from the data of Austrian and American norm populations. Only in the subscale of mental health (MH) the ten-year follow-up did show significantly poorer results (p?=?0.045) compared to the Austrian norm population. The median DASH scores did not show significant differences during the ten-year follow-up period. Conclusion The ten-year results of this single-center study suggest that operative treatment of intra-articular DRF with volar locked plates is a useful and satisfactory therapy option, both in terms of function and HRQOL.



A follow-up study of synthetic rubber workers.  


Although 1,3-butadiene (BD) has been classified as an animal carcinogen, epidemiologic research has reported inconsistent results on the relationship between BD and lymphopoietic and other cancers in humans. This study evaluated the mortality experience of 15649 men employed for at least 1 year at any of eight North American styrene-butadiene rubber (SBR) plants. About 75% of the subjects were exposed to BD; 83% were exposed to styrene (STY). During 1943-1991, the cohort had a total of 386172 and an average of 25 person-years of follow-up, with 3976 deaths observed compared to 4553 deaths expected based on general population mortality rates (standardized mortality ratio (SMR) = 87, 95% confidence interval (CI) = 85-90). More than expected leukemia deaths occurred in the overall cohort (48 observed/37 expected, SMR = 131, CI = 97-174) and among ever hourly subjects (45/32, SMR = 143, CI = 104-191). The excess was concentrated among ever hourly subjects with 10+ years worked and 20+ years since hire (28/13, SMR = 224, CI = 149-323) and among subjects in polymerization (15/6.0, SMR = 251, CI = 140-414), maintenance labor (13/4.9, SMR = 265, CI = 141-453) and laboratories (10/2.3, SMR = 431, CI = 207-793), three areas with potential for relatively high exposure to BD or STY monomers. Some cohort sub-groups had slight increases in deaths from lymphopoietic cancers other than leukemia, but mortality patterns by race, years worked and process group within the SBR industry did not indicate a causal association with occupational exposures. These results indicate that exposures in the SBR industry cause leukemia. PMID:8901897

Delzell, E; Sathiakumar, N; Hovinga, M; Macaluso, M; Julian, J; Larson, R; Cole, P; Muir, D C



Ten-year study of strategies for teaching clinical inference in predoctoral orthodontic education.  


Dealing with the continuum of malocclusions in general practice requires diagnostic skills that, according to the Council on Dental Education guidelines, should include an ability to evaluate the severity of malocclusions and to assess the degree of treatment difficulty. This level of diagnostic skills is predicated upon the ability to make a judgment on the basis of inherently ill-defined and insufficient data or, in other words, upon the ability to use rules and procedures of clinical inference. However, conventional methods of predoctoral orthodontic instruction appear to be unsuitable for transmitting these complex skills to dental students. For ten years, alternative instructional strategies involving guided discovery learning, repetitive practice in application of facts and principles to real-life problems, and eventually a prescriptive diagnostic model were employed at our institution. Both classroom instruction and evaluation were focused on attaining mastery in two narrowly specified domains: "Evaluating the Severity of Malocclusions" and "Assessing the Degree of Treatment Difficulty." The large proportion of items mastered by students and the high percent correct recorded on multiple-choice examinations suggest that these instructional methods may be effective for teaching clinical inference at the predoctoral level of dental education. PMID:3162919

Jacobs, R M



Lung Cancer Survival With Herbal Medicine and Vitamins in a Whole-Systems Approach: Ten-Year Follow-up Data Analyzed With Marginal Structural Models and Propensity Score Methods  

Microsoft Academic Search

Complementary and alternative medicines are used by up to 48% of lung cancer patients but have seen little formal assessment of survival efficacy. In this 10-year retrospective survival study, the authors investigated Pan-Asian medicine + vitamins (PAM+V) therapy in a consecutive case series of all non-small-cell lung cancer patients (n = 239) presenting at a San Francisco Bay Area Chinese

Michael McCulloch; Michael Broffman; Mark van der Laan; Alan Hubbard; Lawrence Kushi; Alan Kramer; Jin Gao; John M. Colford



Ten year follow up of farmers with farmer's lung.  

PubMed Central

Twenty-nine patients previously diagnosed as having suffered from farmer's lung in or before 1970 were asked whether the condition had recurred and what measures they had taken to avoid such recurrence. Those who had retired from farming had been least affected by recurrence, while those who continued to farm had been protected by making silage instead of hay or by wearing protective respirators. To be effective, a respirator should be worn on every occasion that farm dust is encountered and must be properly maintained.

Cuthbert, O D; Gordon, M F



A 10 year follow-up study after Roux-Elmslie-Trillat treatment for cases of patellar instability  

PubMed Central

Background A retrospective study concerning patients presenting with patella instability, treated using a Roux-Elmslie-Trillat reconstruction operation and followed up for 10 years following surgery, is presented. Methods Pre-operative and follow-up radiographic evaluation included the weight-bearing anteroposterior and merchant views. Evaluation was carried out using the Insall-Salvati index, sulcus and congruence angle. The Roux-Elmslie-Trillat reconstruction operation was performed on 18 patients. The clinical evaluation at follow-up was performed using the Knee-Society-Score (KSS) and Tegner-Score. Results Subjective results of the operation were classed as excellent or good in 16 of the 18 patients ten years after surgery; persistent instability of the patella was recorded in only one of the 18 patients. The majority of patients returned to the same level of sporting activity after surgery as they had participated in before injury. Conclusions The Roux-Elmslie-Trillat procedure could be recommended in cases presenting with an increased q-angle, trochlea dysplasia or failed soft tissue surgery. In the present study the majority of patients report a return to previous sporting activity ten years after surgery.



Chemodenervation of strabismic children. A 2- to 5-year follow-up study compared with shorter follow-up.  


To determine longer-term efficacy of botulinum treatment, the author examined 85 children younger than 14 years of age who had been treated from November 1982 to February 1984, comparing shorter follow-up (range, 6-24 months) with longer follow-up (range, 2-5.5 years) as of last examination before March 1988. Fifty esotropes meeting the 2-year criteria for follow-up had an average of 35 prism diopters (PD) before and 5 PD after treatment. Twelve exotropes averaged 30 and 5 PD. No long-term complications were discovered. The results are similar to the shorter follow-up and suggest that botulinum is effective in creating a 2- to 5-year stable improvement for strabismic children. PMID:2771359

Magoon, E H



Ten Year Study of Drug and Alcohol Usage at Middle Tennessee State University.  

ERIC Educational Resources Information Center

This study involved the third administration of a survey of drug and alcohol use among students at Middle Tennessee State University. The original study was completed in 1977 (N=1,551), the second in 1983 (N=1,198), and the third in 1987 (N=1,535). Findings from the 1987 survey revealed that females and fraternity and sorority members were…

Heritage, Jeannette


Western Perceptions of Hong Kong Ten Years on: A Corpus-Driven Critical Discourse Study  

ERIC Educational Resources Information Center

This article studies the Western perceptions of and relations with Hong Kong a decade after the reversion of the sovereignty from Britain to China in 1997. Previous studies have demonstrated that the West had a significantly negative view on the future of Hong Kong with respect to the handover. According to recent observations, however, the…

Cheng, Winnie; Lam, Phoenix W. Y.



Azo dyes and related compounds as important aquatic contaminants: a ten-year case study  

EPA Science Inventory

Mutagenicity has been found in several aquatic systems in the world; however, this activity usually is not associated with any of the compounds that are currently regulated. Attempting to identify these hazardous compounds, an integrated study was conducted, employing several dif...


Ten-Year Trend Analysis of Autism Severity: A Nationwide Population-Based Register Study  

ERIC Educational Resources Information Center

The severity of autism spectrum disorder was strongly related to the education and service outcome. Without a clear profile of autistic population and its change, efforts to understand its nature and improve the quality of service or education will be impossible. The present study aims to describe the over time reported rate of autism severity…

Lin, Jin-Ding; Sung, Chang-Lin; Lin, Lan-Ping; Hsu, Shang-Wei; Chien, Wu-Chien; Su, Sui-Lung; Wu, Jia-Ling



Bioassessment of Alkaline Drainage from Coal Mines in Western Pennsylvania: A Ten-Year Study  

Microsoft Academic Search

Abandoned coal mine drainage (AMD) impacts over 6,500 km of streams in Pennsylvania. AMD alters stream pH and dissolved ions, and often produces precipitated metals that coat stream substrates. We studied 3 streams from 1994 to 2004, before and after treatment wetlands were constructed in 1997-9 to intercept discharges with high iron (60-90 ppm) and alkalinity (100-130 mg\\/L CaCO3) and

C. A. Walter; D. Nelson; J. I. Earle



Bioassessment of Alkaline Drainage from Coal Mines in Western Pennsylvania: A Ten-Year Study  

NASA Astrophysics Data System (ADS)

Abandoned coal mine drainage (AMD) impacts over 6,500 km of streams in Pennsylvania. AMD alters stream pH and dissolved ions, and often produces precipitated metals that coat stream substrates. We studied 3 streams from 1994 to 2004, before and after treatment wetlands were constructed in 1997-9 to intercept discharges with high iron (60-90 ppm) and alkalinity (100-130 mg/L CaCO3) and low manganese and aluminum. Receiving streams are circumneutral with 5-40 ppm total iron and thick iron precipitate. Annual replicate sets of Surber and D nets, rock wash, and leaf packs were sampled. Regression analysis of genus level data showed statistically significant improvement in the two second-order streams. Community profiles are now statistically similar in sites upstream and downstream from AMD. The larger third stream showed moderate AMD impacts before 1997 and no statistically significant biological trends after wetlands substantially decreased levels of AMD in all three streams. This study indicated biological recovery lagged behind chemical recovery by at least 3 years. The patterns of appearance of macroinvertebrate taxa in alkaline AMD sites indicate that commonly used tolerance indices developed for organic pollution do not predict macroinvertebrate responses to AMD. Our study can provide a basis for broader benchmarks in bioassessment of coal mine pollution.

Walter, C. A.; Nelson, D.; Earle, J. I.



Dosimetric Consistency of Co-60 Teletherapy Unit- a ten years Study  

PubMed Central

Objective The goal of the Radiation standards and Dosimetry is to ensure that the output of the Teletherapy Unit is within ±2% of the stated one and the output of the treatment dose calculation methods are within ±5%. In the present paper, we studied the dosimetry of Cobalt-60 (Co-60) Teletherapy unit at Sher-I-Kashmir Institute of Medical Sciences (SKIMS) for last 10 years. Radioactivity is the phenomenon of disintegration of unstable nuclides called radionuclides. Among these radionuclides, Cobalt-60, incorporated in Telecobalt Unit, is commonly used in therapeutic treatment of cancer. Cobalt-60 being unstable decays continuously into Ni-60 with half life of 5.27 years thereby resulting in the decrease in its activity, hence dose rate (output). It is, therefore, mandatory to measure the dose rate of the Cobalt-60 source regularly so that the patient receives the same dose every time as prescribed by the radiation oncologist. The under dosage may lead to unsatisfactory treatment of cancer and over dosage may cause radiation hazards. Our study emphasizes the consistency between actual output and output obtained using decay method. Methodology The methodology involved in the present study is the calculations of actual dose rate of Co-60 Teletherapy Unit by two techniques i.e. Source to Surface Distance (SSD) and Source to Axis Distance (SAD), used for the External Beam Radiotherapy, of various cancers, using the standard methods. Thereby, a year wise comparison has been made between average actual dosimetric output (dose rate) and the average expected output values (obtained by using decay method for Co-60.) Results The present study shows that there is a consistency in the average output (dose rate) obtained by the actual dosimetry values and the expected output values obtained using decay method. The values obtained by actual dosimetry are within ±2% of the expected values. Conclusion The results thus obtained in a year wise comparison of average output by actual dosimetry done regularly as a part of Quality Assurance of the Telecobalt Radiotherapy Unit and its deviation from the expected output data is within the permissible limits. Thus our study shows a trend towards uniformity and a better dose delivery.

Baba, Misba H; Mohib-ul-Haq, M.; Khan, Aijaz A.



A ten-year treatment outcome study of traumatized Cambodian refugees.  


The purpose of this study was to assess treatment outcome among 23 severely traumatized Cambodian refugee patients with posttraumatic stress disorder who had been in continuous treatment for 10 or more years. Primary outcome parameters were symptom severity, social and vocational disability, and subjective quality of life. All patients were interviewed using standard assessment tools by a research psychiatrist not connected with the treatment, and charts were reviewed for past and current traumas and for treatment history. There was a wide range of current posttraumatic stress disorder symptom scores, but current depression scores were very low. Thirteen patients were judged to have good outcomes, and 10 had relatively poor outcomes. Reported degree of previous trauma and demographic factors did not distinguish between the two outcome groups. Sixty percent of patients greatly improved. However, even with comprehensive continuous treatment over a period of 10 or more years, a substantial minority was still impaired. PMID:15457108

Boehnlein, James K; Kinzie, J David; Sekiya, Utako; Riley, Crystal; Pou, Kanya; Rosborough, Bethany



A ten year, multicentre study of coagulase negative staphylococcal infections in Australasian neonatal units  

PubMed Central

Objective: To study late onset systemic infections with coagulase negative staphylococci. Methods: Prospective longitudinal study of coagulase negative staphylococcal infection in 18 Australasian neonatal nurseries. Results: From 1991 to 2000 inclusive, there were 1281 cases of coagulase negative staphylococcal (CoNS) sepsis, comprising 57.1% of all late onset infections. The male/female ratio was 1.27:1 (p < 0.05). The incidence of CoNS sepsis was 3.46 episodes per 1000 live births. Most infected babies (71%) were 24–29 weeks gestation at birth (mode 26 weeks). The first positive culture was day 7–14 in 49% of babies (mode 10 days). Five cases of meningitis were reported, an incidence of 0.4% of all CoNS infections. Twenty nine babies (2.3%) had concurrent necrotising enterocolitis and CoNS septicaemia. Four babies (0.3%) died from CoNS infection, but CoNS infection possibly contributed to the death of an additional 20 babies (1.6%). The mortality directly attributable to CoNS infection was significantly lower than that from late onset infections with Staphylococcus aureus (13.1%; relative risk (RR) = 36.1 (95% confidence interval (CI) 13.0 to 100.2) or with Gram negative bacilli (14.2%; RR = 45.5 (95% CI 16.8 to 123.3)). Conclusions: CoNS are currently responsible for most late onset neonatal infections. Most infected babies are < 30 weeks gestation at birth, and usually present between 7 and 14 days of age. CoNS infections may be associated with necrotising enterocolitis, although causality is unproven. Neonatal CoNS infections are relatively benign: meningitis is rare and mortality low compared with infection from other organisms. Over-vigorous attempts to reduce the incidence of CoNS infections using prophylactic antibiotics are not advisable.

Isaacs, D



Ten years of neonatal autopsies in tertiary referral centre: retrospective study  

PubMed Central

Objectives To measure the neonatal autopsy rate at a tertiary referral centre and identify trends over the past decade. To identify factors that may influence the likelihood of consent being given for autopsy. To examine any discordance between diagnoses before death and at autopsy. Design Retrospective review of patients' records. Setting Tertiary neonatal referral centre affiliated to university. Outcome measures Sex, gestational age, birth weight, type of delivery, and length of stay in neonatal unit for baby. Maternal age, marital status, history of previous pregnancies, and details of who requested permission for autopsy. Concordance between diagnoses before death and at autopsy. Results An autopsy was performed in 209/314 (67%) cases. New information was obtained in 50 (26%) autopsies. In six (3%) cases this information was crucial for future counselling. In 145 (74%) there was complete concordance between the clinical cause of death and the findings at autopsy. From 1994 onwards the autopsy rate in the neonatal unit fell. The only significant factor associated with consent for autopsy was increased gestational age. Conclusions Important extra information can be gained at neonatal autopsies. This should help parents to make an informed decision when they are asked to give permission for their baby to have an autopsy. These findings are of particular relevance in view of the recent negative publicity surrounding neonatal autopsies and the general decline in the neonatal autopsy rate over the decade studied. What is already known on this topicThe neonatal autopsy rate dropped in Illinois during the 10 years from 1984 to 1993Over recent years there has been a large amount of negative publicity surrounding neonatal autopsies in the United KingdomWhat this study addsOver a quarter of neonatal autopsies yielded new information; in 3% of cases this information was crucialThis finding is likely to be of use to bereaved parents who are asked to give permission for autopsy and provides a more positive perspective on the utility of neonatal autopsies

Brodlie, Malcolm; Laing, Ian A; Keeling, Jean W; McKenzie, Kathryn J



Patient preferences at ten years following initial diagnosis of atrial fibrillation: the Belgrade Atrial Fibrillation Study  

PubMed Central

Background Many atrial fibrillation (AF) patients have a poor understanding of the management of this condition. We investigated patient attitudes towards AF and a potential invasive treatment following an average 10-year period of prospective rhythm control in a cohort of newly diagnosed AF patients. Methods This was a prospective registry-based study. At the regular annual visit in 2007, patients were asked at random to answer several AF-related questions. Results Of 390 patients, 277 (71.0%) reported symptom reduction over time, but only 45 (11.5%) reported that they had “got used” to AF; 201 patients (51.5%) stated they would always prefer sinus rhythm, and 280 (71.2%) would accept an invasive AF treatment. Independent predictors for choosing an invasive procedure were younger age, impaired career/working capacity, and male gender (all P < 0.05). Conclusion Our findings suggest that most AF patients prefer sinus rhythm and would readily accept an invasive procedure if it offered the possibility of a cure for their AF.

Potpara, Tatjana S; Polovina, Marija M; Mujovic, Nebojsa M; Kocijancic, Aleksandar M; Lip, Gregory YH



Does Avoidant Coping Influence Young Adults' Smoking?: A Ten-Year Longitudinal Study  

PubMed Central

Introduction: Young adults who avoid their emotions may be at risk for starting smoking or not quitting smoking. This study investigated whether a preliminary measure of avoidant coping longitudinally predicts young adults’ smoking escalation and cessation. Methods: In a sample of the 3,305 participants, originally from Washington State, a preliminary measure of self-reported avoidant coping at age 18 was used to predict both smoking escalation and cessation at ages 20 and 28 with both probability and logistic regression models (10-year retention: 98.5%). Results: Individuals who scored high on avoidant coping at 18 were 2.52 (p = .001) times more likely to acquire smoking by 20. However, there was no evidence that avoidant coping at age 18 predicted smoking escalation at 28 or cessation for 20- and 28-year-olds. Conclusions: An avoidant coping style may have a short-term effect on young adults’ smoking acquisition. Future research using a precise and well-validated measure of avoidant coping is now needed to test this possibility.

Schiff, Lara; Comstock, Bryan A.



Epidemiology of mesothelioma in Egypt. A ten-year (1998-2007) multicentre study  

PubMed Central

Introduction Mesothelioma is a cancer strongly linked to exposure to carcinogenic minerals, especially asbestos. The aim of the study was to detect the incidence of malignant pleural mesothelioma (MPM) in Egypt, to clarify the impact of occupational and environmental risk factors, and to characterise its demographic features. Material and methods They were 584 cases diagnosed as MPM detected in Cairo University Hospitals and National Cancer Institute from 1998 to 2007. Unfortunately, full epidemiological data were only available for 165 cases due to absence of a reliable registration system. Results A steady increase in the number of cases was detected, from 24 in 1998, peaking at 82 cases in 2005, followed by a gradual decline (though still high) with 68 cases in 2006 and 51 cases in 2007. Male/female ratio was 1.35/1 (p > 0.05). The occupational exposure to asbestos was 13.9%. Residential exposure plays a major role in two regions, Helwan and Shoubra (27.3% and 20.6% respectively), while in Upper and Lower Egypt the level was 12.7% and 17.5% respectively. Kaplan-Meier survival for sex, residence and the pathological types epithelioid, biphasic and sarcomatoid was insignificant. The median survival for different grades and treatment modalities was significant (P < 0.001). Conclusions There was a steady increase in the incidence of MPM from 1998 to 2005 followed by a decline during 2006-2007. Mesothelioma in Egypt is mainly concentrated in areas of high environmental pollution. The decline within the last 2 years may be attributed to recent strict industrial preventive measures. However, a better environmental control programme would benefit Egypt.

Akl, Yosri; Kaddah, Safy; Abdelhafeez, Ahmed; Salah, Randa; Lotayef, Mohamed



Adverse events of intravenous immunoglobulin infusions: a ten-year retrospective study  

PubMed Central

Background Intravenous immunoglobulin (IVIG) is a biological product with adverse effects that appears to vary considerably among different IVIG preparations. Objectives To describe the adverse events of patients given intravenous immunoglobulin infusions. Method Data was collected on all patients receiving IVIG infusion at a tertiary hospital from January 2001 to December 2010. Descriptive statistics was used. Results 77 patients (45 males, 32 females) received IVIG infusions. Thirty two percent (n = 25) experienced adverse reactions. The most common indication was Kawasaki disease (85.7%) followed by immunodeficiency disorders (7.8%). Majority of the patients were children, with the highest frequency of infusions among those aged 2 to 8 years old (52%). 36 infusions were associated with occurrence of adverse effects. Fever was the most common adverse event (n = 11, 30.6%), followed by rash (n = 8, 22.2%) and chills (n = 7, 19.4%). Other adverse events were cyanosis (n = 3, 8.3%), hypotension (n = 2, 5.6%), hypothermia (n = 2, 5.6%), irritability (n = 1, 2.8%), vomiting (n = 1, 2.8%), and chest pain (n = 1, 2.8%). Adverse events were observed to occur most frequently within 1 to 6 h from onset of IVIG infusion. Among the various IVIG preparations available locally (Gammagard, Kiovig, Gamimune, Veno-S & IV Globulin S), Gammagard was the brand frequently used (50.7%). It also has the most number of adverse events, with 17 out of 41 (41.5%) infusions resulting in adverse reactions. Most of the reactions occurred with fast infusion rates, and clinical manifestations subsided when the rate of infusion was reduced. Conclusion In this study, thirty two percent of patients given IVIG infusions experienced adverse events. Fever was the most common manifestation. Symptoms occurred within 1 to 6 h from onset of infusion, were affected by fast infusion rates, and managed by reducing the rate of infusion.

Kwong, Shirley L.; Padua, Florecita R.



Ten-Year Retrospective Longitudinal-Study of Student Perspectives on Value of REU  

NASA Astrophysics Data System (ADS)

For more than two decades, federal agencies have been enthusiastically supporting summer research experiences for undergraduates. These REU programs are tacitly intended to increase retention and provide "an important educational experience" for undergraduates, particularly women, minorities and underrepresented groups. Numerous authors (viz., Laursen, Lopatto, Dolan, among many others) have enthusiastically described positive impacts of summer REU programs from exit interview data. These results include enhanced persistence to pursue STEM careers and confirmed desire to attend graduate school in the field targeted by a particular REU. Perhaps surprisingly, negative student experiences are rarely described in the scholarly literature, but do appear in more informal publications (viz., Gueterma, 2007). One wonders how REU alumni, looking back over their entire collective portfolio of experiences, now perceive the educational value of their REU experience relative to their other educational experiences. To obtain a backwards-looking, reflective description from REU alumni on the value of their REU experiences, we conducted a 10-year, two-stage study was designed to explore the ways in which the REU acted as an educational experience for 51 women from a single geoscience sub-discipline. The first phase was an ex post facto longitudinal analysis of data, including multiple interviews with each participant during their REU, annual open-ended alumni surveys, faculty interviews, and extensive field notes, over a 10-year period. This analysis informed the second phase, a clinical interview. Over 10 hours of interviews with 8 participants were conducted and analyzed. These 8 participants were selected to represent a variety of career stages, and for their potential to reflect on a wide variety of educational experiences. Results from the interviews, done many years after their REU experience, indicate that the interviewees' REU did not provide a substantive educational experience related to the nature of scientific work, the scientific process, or the culture of academia when considered in a comparative context of students' other educational experiences. Results further indicated that the REU did not serve to transform participants' conceptions about themselves as situated in science, and learning gains with regard to other aspects of the self, were somewhat limited. Instead, the data suggests that these women arrived at the REU with pre-existing and remarkably strong conceptions in these areas, and that the REU did not functional to alter those states. These conceptions were frequently the result of interactions with mentors/scientists from middle school until well into the undergraduate period.

Slater, T. F.; Slater, S. J.



Day Care Training in Alabama: A Follow-Up Study.  

ERIC Educational Resources Information Center

This study reports information gathered from 82 of the 1,056 child care workers who participated in the Alabama Statewide Day Care Training Project, the first comprehensive training program for child care providers in the state. The project sponsored training workshops in four regions of the state and included correspondence study as an option.…

Eddowes, E. Anne; Martin, Kathleen


New polyethylenes in total hip replacement: A ten- to 12-year follow-up study.  


Between 1999 and 2001, 90 patients underwent total hip replacement using the same uncemented acetabular and femoral components with a 28 mm metallic femoral head but with prospective randomisation of the acetabular liner to either Durasul highly cross-linked polyethylene or nitrogen-sterilised Sulene polyethylene. We assessed 83 patients at a minimum follow-up of ten years. Linear penetration of the femoral head was estimated at six weeks, six and 12 months and annually thereafter, using the Dorr method, given the non-spherical shape of the acetabular component. There was no loosening of any component; only one hip in the Sulene group showed proximal femoral osteolysis. The mean penetration of the femoral head at six weeks was 0.08 mm (0.02 to 0.15) for the Durasul group and 0.16 mm (0.05 to 0.28) for the Sulene group (p = 0.001). The mean yearly linear penetration was 64.8% lower for the Durasul group at 0.05 mm/year (sd 0.035) for the Sulene group and 0.02 mm/year (sd 0.016) for the Durasul (p < 0.001). Mean linear femoral head penetration at ten years was 61% less in the Durasul than Sulene group. Highly cross-linked polyethylene gives excellent results at ten years. PMID:23450015

García-Rey, E; García-Cimbrelo, E; Cruz-Pardos, A



A Follow-Up Study of Non-Returning Students.  

ERIC Educational Resources Information Center

In spring 1987, a study was conducted at Monroe Community College (MCC) to determine the factors which influence attrition and retention, with particular focus on the reasons why students who have not graduated fail to return for succeeding semesters. Questionnaires were mailed to 452 former students, requesting information on students' rankings…

Cotnam, John D.; Ison, Sherrill


A Follow-Up Study of Abused Children  

ERIC Educational Resources Information Center

Investigated in a followup study of 219 NAT (non-accidental trauma) children and 159 NEG (gross neglect) children were the specific effects of abusive environments on psychosocial development and the possible reversibility of these effects with intervention through foster home placement. Available from: EC 090 265. (Author/IM)

Kent, James T.



Communicating serum chemical concentrations to study participants: follow up survey  

PubMed Central

Background A considerable literature now supports the importance of effective communication with study participants, including how best to develop communication plans focusing on the uncertainty of health risks associated with particular environmental exposures. Strategies for communicating individual concentrations of environmental chemicals in human biological samples in the absence of clearly established safe or hazardous levels have been discussed from a conceptual basis and to a lesser extent from an empirical basis. We designed and evaluated an empirically based communication strategy for women of reproductive age who previously participated in a prospective study focusing on persistent environmental chemicals and reproductive outcomes. Methods A cohort of women followed from preconception through pregnancy or up to 12 menstrual cycles without pregnancy was given their individual serum concentrations for lead, dichloro-2,2-bisp-chlorophenyl ethylene, and select polychlorinated biphenyl congeners. Two versions of standardized letters were prepared depending upon women's exposure status, which was characterized as low or high. Letters included an introduction, individual concentrations, population reference values and guidance for minimizing future exposures. Participants were actively monitored for any questions or concerns following receipt of letters. Results Ninety-eight women were sent letters informing them of their individual concentrations to select study chemicals. None of the 89 (91%) participating women irrespective of exposure status contacted the research team with questions or concerns about communicated exposures despite an invitation to do so. Conclusions Our findings suggest that study participants can be informed about their individual serum concentrations without generating unnecessary concern.



3-Year Follow-up of the NIMH MTA Study  

ERIC Educational Resources Information Center

Objective: In the intent-to-treat analysis of the Multimodal Treatment Study of Children With ADHD (MTA), the effects of medication management (MedMgt), behavior therapy (Beh), their combination (Comb), and usual community care (CC) differed at 14 and 24 months due to superiority of treatments that used the MTA medication algorithm (Comb+MedMgt)…

Jensen, Peter S.; Arnold, L. Eugene; Swanson, James M.; Vitiello, Benedetto; Abikoff, Howard B.; Greenhill, Laurence L.; Hechtman, Lily; Hinshaw, Stephen P.; Pelham, William E.; Wells, Karen C.; Conners, C. Keith; Elliott, Glen R.; Epstein, Jeffery N.; Hoza, Betsy; March, John S.; Molina, Brooke S. G.; Newcorn, Jeffrey H.; Severe, Joanne B.; Wigal, Timothy; Gibbons, Robert D.; Hur, Kwan



Hydrotherapy after total hip arthroplasty: a follow-up study.  


The aim of the study was to evaluate the subjective functional outcome of total hip arthroplasty (THA) in patients who underwent hydrotherapy (HT) 6 months after discharge. A prospective randomized study was performed on 70 elderly inpatients with recent THA, who completed a rehabilitation program. After randomization, 33 of them were treated in conventional gyms (no-hydrotherapy group=NHTG) and 31 received HT (hydrotherapy group=HTG). Interviews with the Western-Ontario MacMasters Universities Osteoarthritis Index (WOMAC) were performed at admission, at discharge and 6 months later. Kruskal-Wallis, Mann-Whitney and Wilcoxon tests were applied for statistical analysis. Both groups improved. Pain, stiffness and function were all positively affected. Statistical analysis indicated that WOMAC sub-scales were significantly lower for all patients treated with HT. The benefits at discharge still remained after 6 months. We conclude that HT is recommended after THA in a geriatric population. PMID:19282040

Giaquinto, S; Ciotola, E; Dall'armi, V; Margutti, F



A follow-up study of synthetic rubber workers  

Microsoft Academic Search

Although 1,3-butadiene (BD) has been classified as an animal carcinogen, epidemiologic research has reported inconsistent results on the relationship between BD and lymphopoietic and other cancers in humans. This study evaluated the mortality experience of 15649 men employed for at least 1 year at any of eight North American styrene-butadiene rubber (SBR) plants. About 75% of the subjects were exposed

Elizabeth Delzell; Nalini Sathiakumar; Mary Hovinga; Maurizio Macaluso; Jim Julian; Rodney Larson; Philip Cole; David C. F. Muir



Multicenter follow-up study of the transmandibular implant.  


The purpose of this multicenter study was to review the results of treatment and identify complications in edentulous patients who were treated with the transmandibular implant. A total of 190 patients were treated in four university departments. These patients presented for treatment with mandibular bone heights that ranged from 4 to 18 mm (mean, 10 mm). After postoperative periods that ranged from 3 months to 5 years, 182 of the 190 implants (95.8%) were stable and functional. Three implants were removed due to perioperative fractures in mandibles with 4 to 6 mm of bone height. Five were removed due to infection which occurred within the first 3 months after surgery. Reversible complications that developed in 22.2% of the patients were treated successfully. The 182 implants in function demonstrated no mobility and no infrabony pockets around any of the transmucosal posts. The results of this study demonstrate that the transmandibular implant has acceptable predictability and reliability for reconstruction of patients with severe atrophy of the mandibular alveolar process. PMID:2664104

Maxson, B; Sindet-Pedersen, S; Tideman, H; Fonseca, R J; Zijlstra, G



Follow-up Study of Patients With Cerebral Palsy  

PubMed Central

Of 319 patients with cerebral palsy recalled for reevaluation 15 years after the initial visit, 10 percent had died. Of the living, 55 percent had spasticity, 32 percent had athetosis, 4 percent had ataxia and 9 percent had mixed spasticity and athetosis; 38 percent had an intelligence quotient (IQ) less than 50, 24 percent between 50 and 79, and 38 percent had IQ above 80. There was a high correlation between overall functional outcome and intellectual level. Severity of physical disability, as measured by hand use, mobility and speech, also correlated with dependence, in part because increased severity of the disability was associated with decreased intellectual capacity generally. Twenty-five years after the initial visit, parental attitudes and personality intactness were evaluated (using the Minnesota Multiphasic Personality Inventory [MMPI]) and were correlated with satisfaction with status in life in 28 persons predicted to be independent on the 15-year study. Twenty (72 percent) of the 28 were satisfied with their status in life and of these, 16 were evaluated (with the MMPI) with 70 percent scoring in the normal range; 13 (65 percent) had parents with a positive attitude. Positive attitude was defined as parental feelings that the handicapped child was a worthy, valuable person, to be encouraged and assisted but not isolated from the world of nonhandicapped people. Careful serial assessment by professional teams combined with repeated long-term counseling of families can result in optimal outcome for the disability level involved, due to the primary role parents play in the development of a child's character and behavior.

Cohen, Peter; Kohn, Jean G.



Barriers to follow-up for pediatric cataract surgery in Maharashtra, India: How regular follow-up is important for good outcome. The Miraj Pediatric Cataract Study II  

PubMed Central

Background: Regular follow up and amblyopia treatment are essential for good outcomes after pediatric cataract surgery. Aim: To study the regularity of follow-up after cataract surgery in children and to gauge the causes of poor compliance to follow up. Subjects: 262 children (393 cataracts) who underwent cataract surgery in 2004-8. Materials and Methods: The children were identified and examined in their homes and a “barriers to follow-up” questionnaire completed. Demographic data collected, visual acuity estimated, and ocular examination performed. Statistical Analysis: SPSS version 19. Results: Of the 262 children, only 53 (20.6%) had been regularly following up with any hospital, 209 (79.4%) had not. A total of 150 (57.3%) were boys and the average age was 13.23 years (Std Dev 5 yrs). Poor follow up was associated with the older age group (P < 0.001), less education of mother (P = 0.012), father's occupation (P = 0.031), how much money spent on travel (P = 0.033) and was it paid or free surgery (P = 0.001). It was not related to gender, numbers of children in family, ordinal status of child, and social strata. Distance and cost were major barriers, as was the inability of the eye care center to communicate the importance of follow up. A prospective follow-up visit showed that 93 children needed Nd: YAG LASER capsulotomy, 5 needed low vision aids, 4 contact lens, and 162 a change of spectacles. The average visual acuity improved in 150 (38.8%) eyes >1 line with regular follow-up. Conclusion: Regular follow-up is important and improves vision; eye care practitioners need to take special efforts to ensure better follow-up.

Gogate, Parikshit; Patil, Shailbala; Kulkarni, Anil; Mahadik, Ashok; Tamboli, Rahin; Mane, Rekha; Borah, Rishiraj; Rao, G V



A Follow-Up Study of Marines Two and a Half Years after Recruit Training.  

National Technical Information Service (NTIS)

This report describes a follow-up study of 228 Marines two and a half years after they received recruit training at MCRD, San Diego. A sample of Marines who began recruit training in October 1978 participated in a follow-up study. The subjects completed a...

I. G. Sarason R. W. Novaco B. R. Sarason



The RETHINK Parenting and Anger Management Program: A Follow-Up Validation Study  

ERIC Educational Resources Information Center

This study is the first follow-up assessment of the RETHINK Parenting and Anger Management Program. Parent participants (N = 168) reduced their anger, violence, and family conflict levels from posttest to follow-up, on average, at 2.5 months on 13 of 15 dependent variables. Current findings are consistent with a small, albeit growing body of…

Fetsch, Robert J.; Yang, Raymond K.; Pettit, Matthew J.



Ten years of progress in the Hokkaido birth cohort study on environment and children's health: cohort profile--updated 2013.  


The Hokkaido Study on Environment and Children's Health is an ongoing cohort study that began in 2002. The study consists of two prospective birth cohorts, the Sapporo cohort (n = 514) and the Hokkaido large-scale cohort (n = 20,940). The primary goals of this study are to first examine the potential negative effects of perinatal environmental chemical exposures on birth outcomes, including congenital malformations and growth retardation; second, to evaluate the development of allergies, infectious diseases and neurodevelopmental disorders and perform longitudinal observations of the children's physical development to clarify the causal relationship between these outcomes and environmental chemicals; third, to identify individuals genetically susceptible to environmental chemicals; finally, to identify the additive effects of various environmental factors in our daily life, such as secondhand smoke exposure or low folate intake during early pregnancy. In this paper, we introduce our recent progress in the Hokkaido study with a cohort profile updated in 2013. For the last ten years, we followed pregnant women and their offspring, measuring various environmental chemicals, i.e., PCB, OH-PCB and dioxins, PFCs (Perfluorinated Compounds), Organochlorine pesticides, Phthalates, bisphenol A and mercury. We discovered that the concentration of toxic equivalents (TEQ) of dioxin and other specific congeners of PCDF or PCDD have effects on birth weight, infants' neurodevelopment and immune function. There were significant gender differences in these effects; our results suggest that male infants have more susceptibility to those chemical exposures than female infants. Interestingly, we found maternal genetic polymorphisms in AHR, CYP1A1 or GSTs that significantly modified the dioxin concentrations in maternal blood, suggesting different dioxin accumulations in the bodies of individuals with these genotypes, which would lead to different dioxin exposure levels. These genetic susceptibility factors influenced the body size of children born from mothers that either smoked or were passively exposed to tobacco smoke. Further studies investigating the correlation between epigenetics, the effects of intrauterine exposure to environmental chemicals and developmental factors related to health and disease are warranted. PMID:23959649

Kishi, Reiko; Kobayashi, Sachiko; Ikeno, Tamiko; Araki, Atsuko; Miyashita, Chihiro; Itoh, Sachiko; Sasaki, Seiko; Okada, Emiko; Kobayashi, Sumitaka; Kashino, Ikuko; Itoh, Kumiko; Nakajima, Sonomi



Systematic bias in traumatic brain injury outcome studies because of loss to follow-up  

Microsoft Academic Search

Corrigan JD, Harrison-Felix C, Bogner J, Dijkers M, Terrill MS, Whiteneck G. Systematic bias in traumatic brain injury outcome studies because of loss to follow-up. 2003;84:153-60. Objective: To identify potential sources of selection bias created by subjects lost to follow-up in studies of traumatic brain injury (TBI). Design: Demographic, premorbid, injury-related, and hospital course characteristics were compared for subjects lost

John D. Corrigan; Cynthia Harrison-Felix; Jennifer Bogner; Marcel Dijkers; Melissa Sendroy Terrill; Gale Whiteneck



How persistent is ADHD? A controlled 10-year follow-up study of boys with ADHD  

Microsoft Academic Search

The main aim of this study was to examine the age-dependent persistence of attention-deficit hyperactivity disorder (ADHD) in boys transitioning from adolescence into early adulthood attending to different definitions of persistence. We conducted a 10-year follow-up study (mean follow-up time=11years) of 110 boys with ADHD and 105 non-ADHD controls. Both groups were 6–17years of age at ascertainment. ADHD was considered

Joseph Biederman; Carter R. Petty; Maggie Evans; Jacqueline Small; Stephen V. Faraone



A Follow Up Study of Vibration-Induced White Finger in Compensation Claimants  

Microsoft Academic Search

The aim of this follow up clinical study was to investigate the changes in vascular symptoms and the cold response of digital vessels in 73 vibration-exposed workers claiming for VWF compensation. The subjects were followed up over a mean time period of 4.1 (range 1-11) years. They underwent a medical interview, a physical examination and a standardised cold test with

Massimo Bovenzi; Anna Della Vedova; Corrado Negro



Neuropsychological assessment in multiple sclerosis: a follow-up study with magnetic resonance imaging  

Microsoft Academic Search

Nineteen moderately impaired patients with clinically definite multiple sclerosis and an initially relapsing-remitting course were included in a neuropsychological and magnetic resonance imaging (MRI) follow-up study. The average test\\/re-test interval was about 2 years. The neuropsychological findings were indicative of a very mild overall impairment; the patients, as a group, showed no evidence of cognitive deterioration in the follow-up period.

C. Mariani; E. Farina; S. F. Cappa; G. P. Anzola; L. Faglia; L. Bevilacqua; R. Capra; F. Mattioli; L. A. Vignolo




PubMed Central

SUMMARY This paper describes the results of a five year follow up study on factors associated with the course and outcome of schizophrenia conducted in 3 centers (Lucknow, Madras and Vellore) under the auspices of the Indian Council of Medical Research. 386 patients who satisfied well defined criteria of diagnosis and inclusion and exclusion criteria were studied. All patients were regularly followed up. 287 patients had complete follow up after 5 years. After 2 years, most of the active symptoms had subsided. At 5 year follow up, about 67% of the patients showed good outcome. Regular drug compliance, short duration of illness, absence of economic difficulties, absence of dangerous behaviour and delusions of presecution at intake; presence of agitation at intake; acute onset, absence of schizoid traits in personality, low level of education, rural background and lower age of onset were significantly related to good outcome. A combination of 8 factors could correctly predict the outcome in 80% of patients. The implications of the above findings are discussed.

Verghese, A.; Dube, K.C.; John, J.K.; Kumar, N.; Nandi, D.N.; Parhee, R.; Rajkumar, S.; Richard, J.; Menon, Sarada M.; Sethi, B.B.; Trivedi, J.K.



A ten-year study on the physiology of two Spanish grapevine cultivars under field conditions: effects of water availability from leaf photosynthesis to grape yield and quality  

Microsoft Academic Search

The effects of moderate irrigation, compared with non-irrigation, on leaf photosynthesis and transpiration, grape yield, and quality parameters, were studied over ten years in two Spanish cultivars (Tempranillo and Manto Negro) of field-grown grapevines (Vitis vinifera L.). The aim was to increase our knowledge of the relationships between water availability, canopy water losses, photosynthesis, and fruit yield and quality. A

Hipólito MedranoA; José M. EscalonaA; Jaume FlexasA


Description of a ten year study of the preengineering program for under-represented, low income and\\/or first generation college students at The University of Akron  

Microsoft Academic Search

This paper summarizes ten years' efforts of a preengineering program to improve the recruitment and retention of under-represented students pursuing careers in science, mathematics, engineering, and technology (SMET) at The University of Akron. This study, evaluates The University of Akron's successful operations of the special high school upward bound and the preengineering programs to increase the number of under-represented students

Paul Lam; P. Ruby Mawasha; Tirumalai Srivatsan; John Vesalo



Longitudinal Studies With Outcome-Dependent Follow-up: Models and Bayesian Regression  

PubMed Central

We propose Bayesian parametric and semiparametric partially linear regression methods to analyze the outcome-dependent follow-up data when the random time of a follow-up measurement of an individual depends on the history of both observed longitudinal outcomes and previous measurement times. We begin with the investigation of the simplifying assumptions of Lipsitz, Fitzmaurice, Ibrahim, Gelber, and Lipshultz, and present a new model for analyzing such data by allowing subject-specific correlations for the longitudinal response and by introducing a subject-specific latent variable to accommodate the association between the longitudinal measurements and the follow-up times. An extensive simulation study shows that our Bayesian partially linear regression method facilitates accurate estimation of the true regression line and the regression parameters. We illustrate our new methodology using data from a longitudinal observational study.

Ryu, Duchwan; Sinha, Debajyoti; Mallick, Bani; Lipsitz, S. L.; Lipshultz, S.



Sierra Leone's Former Child Soldiers: A Follow-up Study of Psychosocial Adjustment and Community Reintegration  

PubMed Central

This is the first prospective study to investigate psychosocial adjustment in male and female former child soldiers (n=156, 12% female). The study began in Sierra Leone in 2002 and was designed to examine both risk and protective factors in psychosocial adjustment. Over the two-year period of follow up, youth who had wounded or killed others during the war demonstrated increases in hostility. Youth who survived rape had higher levels of anxiety and hostility, but also demonstrated greater confidence and prosocial attitudes at follow up. Of the potential protective resources examined, improved community acceptance was associated with reduced depression at follow up and improved confidence and prosocial attitudes regardless of levels of violence exposure. Retention in school was also associated with greater prosocial attitudes.

Betancourt, Theresa Stichick; Borisova, Ivelina Ivanova; Williams, Timothy Philip; Brennan, Robert T.; Whitfield, T. Hatch; de la Soudiere, Marie; Williamson, John; Gilman, Stephen E.



Sierra Leone's former child soldiers: a follow-up study of psychosocial adjustment and community reintegration.  


This is the first prospective study to investigate psychosocial adjustment in male and female former child soldiers (ages 10-18; n = 156, 12% female). The study began in Sierra Leone in 2002 and was designed to examine both risk and protective factors in psychosocial adjustment. Over the 2-year period of follow-up, youth who had wounded or killed others during the war demonstrated increases in hostility. Youth who survived rape not only had higher levels of anxiety and hostility but also demonstrated greater confidence and prosocial attitudes at follow-up. Of the potential protective resources examined, improved community acceptance was associated with reduced depression at follow-up and improved confidence and prosocial attitudes regardless of levels of violence exposure. Retention in school was also associated with greater prosocial attitudes. PMID:20636683

Betancourt, Theresa Stichick; Borisova, Ivelina Ivanova; Williams, Timothy Philip; Brennan, Robert T; Whitfield, Theodore H; de la Soudiere, Marie; Williamson, John; Gilman, Stephen E



The Acculturation of a Group of Lithuanian Women: A Follow-Up Study.  

ERIC Educational Resources Information Center

Presents a study of Lithuanian refugees involving 24 women and spanning 16 years, from the original study done in 1957 in Chicago, to the follow-up study of 14 of the same respondents done in 1973-74. Describes their process of acculturation in different life areas, their attitudes, and their associations. (Executive Office of the AABS, 231 Miller…

Cernius, Vytautas J.



Adolescents' Declining Motivation to Learn Science: A Follow-Up Study  

ERIC Educational Resources Information Center

This is a mix methods follow-up study in which we reconfirm the findings from an earlier study [Vedder-Weiss & Fortus [2011] "Journal of Research in Science Teaching, 48(2)", 199-216]. The findings indicate that adolescents' declining motivation to learn science, which was found in many previous studies [Galton [2009] "Moving to secondary school:…

Vedder-Weiss, Dana; Fortus, David



Nursing Education Follow-Up Study--1982 R.N.'s.  

ERIC Educational Resources Information Center

In 1982, a follow-up study of nursing graduates of the Bakersfield College Registered Nursing (RN) program was conducted to obtain information that would lead to improvement in program quality and to a better match between supply and demand in the local nursing labor market. In addition, the study compared results with similar studies conducted…

Scott, David C.


Managerial quality, administrative performance and trust in governance revisited : A follow-up study of causality  

Microsoft Academic Search

Reports on a follow-up study of the relationship between managerial quality, administrative performance and citizens’ trust in government and in public administration systems. The study was based on a survey of 502 Israeli citizens conducted during 2002 and was compared with a similar study that was conducted during 2001 among 345 Israeli citizens. The research tried to validate and replicate

Eran Vigoda-Gadot; Fany Yuval



Pre-Placement Anxiety among Foundation-Year MSW Students: A Follow-up Study  

ERIC Educational Resources Information Center

This Field Note presents a follow-up to a pilot study that explored pre-field placement anxiety for 1st-year MSW students. Previous studies report that students experience significant anxiety as they anticipate their field placement, and research indicates that anxiety has the potential to affect learning. A sample of 204 students reported…

Rosenthal Gelman, Caroline; Lloyd, Chrishana M.



Follow-Up Study of 1986 Harper Career Alumni. Volume XVI, No. 9.  

ERIC Educational Resources Information Center

As part of an ongoing evaluation of the career programs at Illinois' William Rainey Harper College (WRHC), a follow-up study of 1986 program graduates was conducted and results were compared with previous years. Questionnaires were sent to 491 students who earned 48 or more hours during the 1985-86 academic year at WRHC. Study findings, based on a…

Lucas, John A.


Extending a Community of Care beyond the Ninth Grade: A Follow-Up Study  

ERIC Educational Resources Information Center

This qualitative within-site case study ("N" = 10) is a follow-up study to a 2006-2007 investigation that analyzed how 1 high school created a community of care for its ninth-grade students through the implementation of a ninth-grade transition program--Freshman Focus. All participants were interviewed again 3 years later during…

Ellerbrock, Cheryl R.; Kiefer, Sarah M.



West Los Angeles College Student Follow-Up Study Project Report.  

ERIC Educational Resources Information Center

A follow-up study was conducted among new students at West Los Angeles College (WLAC) to identify student characteristics, educational goals, and objectives; and to relate these characteristics to student attrition. Subjects for the study were 483 first-time freshmen enrolled at WLAC in Fall 1977. This initial sample was surveyed again one year…

Garber, Robert


Liver disease in ulcerative colitis: an epidemiological and follow up study in the county of Stockholm  

Microsoft Academic Search

In an epidemiological study of the incidence of ulcerative colitis (UC) in the county of Stockholm between 1955 and 1979, 1274 patients with UC were discovered. Almost all these patients had regularly been investigated with liver function tests; 142 (11%) of them showed signs of hepatobiliary disease. A follow up study on all 142 patients with abnormal liver function and

U Broomé; H Glaumann; G Hellers; B Nilsson; J Sörstad; R Hultcrantz



Sierra Leone's Former Child Soldiers: A Follow-Up Study of Psychosocial Adjustment and Community Reintegration  

ERIC Educational Resources Information Center

This is the first prospective study to investigate psychosocial adjustment in male and female former child soldiers (ages 10-18; n = 156, 12% female). The study began in Sierra Leone in 2002 and was designed to examine both risk and protective factors in psychosocial adjustment. Over the 2-year period of follow-up, youth who had wounded or killed…

Betancourt, Theresa Stichick; Borisova, Ivelina Ivanova; Williams, Timothy Philip; Brennan, Robert T.; Whitfield, Theodore H.; de la Soudiere, Marie; Williamson, John; Gilman, Stephen E.



Sources of Validity Evidence for Educational and Psychological Tests: A Follow-Up Study  

ERIC Educational Resources Information Center

This study followed up on previous work that examined the incidence of reporting evidence based on test consequences in "Mental Measurements Yearbook". In the present study, additional possible outlets for what has been called "consequential validity" evidence were investigated, including all articles published in the past 10 years in several…

Cizek, Gregory J.; Bowen, Daniel; Church, Keri



The Course and Outcomes of Episodic Endogenous Psychoses with Juvenile Onset (a follow-up study)  

Microsoft Academic Search

A clinical follow-up study (mean follow-up period 16.8 ± 6.4 years) of 278 patients with juvenile-onset endogenous episodic\\u000a psychosis (Endogenous Psychosis Episodic Type, EPET – ICD-10 F20.03, F20.23, F25) with first episodes in 1984–1995 was performed.\\u000a The period of the most intense occurrence of repeated episodes occurred during the first five years from the initial episode\\u000a (almost all repeat episodes

V. G. Kaleda



Dietary changes in Vietnamese marriage immigrant women: The KoGES follow-up study  

PubMed Central

BACKGROUND/OBJECTIVES The immigrant population has grown considerably in South Korea since the early 1990s due to international marriages. Dietary changes in immigrants are an important issue, because they are related to health and disease patterns. This study was conducted to compare changes in dietary intake between baseline and follow-up periods. SUBJECTS/METHODS Two hundreds thirty three Vietnamese female married immigrants. Baseline data were collected during 2006-2009, and the follow-up data were collected during 2008 and 2010. Food consumption was assessed using a 1-day 24-hour recall. RESULTS The amount of the total food consumed (P < 0.001) including that of cereals (P = 0.004), vegetables (P = 0.003), and fruits (P = 0.002) decreased at follow-up compared to that at baseline, whereas consumption of milk and dairy products increased (P = 0.004). Accordingly, the overall energy and nutrient intake decreased at follow-up, including carbohydrates (P = 0.012), protein (P = 0.021), fiber (P = 0.008), iron (P = 0.009), zinc (P = 0.006), and folate (P = 0.002). Among various anthropometric and biochemical variables, mean skeletal muscle mass decreased (P = 0.012), plasma high density lipoprotein-cholesterol increased, (P = 0.020) and high sensitivity C-reactive protein decreased at follow-up (P < 0.001). CONCLUSIONS A long-term follow-up study is needed to investigate the association between changes in food and nutrient intake and anthropometric and biochemical variables in these Vietnamese female marriage immigrants.

Hwang, Ji-Yun; Lee, Hakim; Ko, Ahra; Han, Chan-Jung; Chung, Hye Won



Follow-Up Study of 1986 Nursing Graduates. Volume XVI, No. 12.  

ERIC Educational Resources Information Center

In spring 1987, a follow-up study of nursing program graduates was conducted at William Rainey Harper College (WRHC) to examine employment patterns, further education plans, and graduates' evaluation of particular aspects of their WRHC experience. Questionnaires were mailed to 112 nursing students who graduated with an associate degree in 1986.…

Dincher, J.; Flaherty, A.


Follow-Up Study of 1992 Nursing Graduates. Volume XXII, Number 15, March 1994.  

ERIC Educational Resources Information Center

In an attempt to evaluate the effectiveness of its nursing program, William Rainey Harper College (WRHC) (Illinois) conducted a follow-up study of 1992 nursing graduates or alumni. In spring 1993, a survey instrument, inquiring about employment status, future educational plans, and evaluation of their experience at WRHC, was mailed to all 142 WRHC…

Lucas, John A.; Meltesen, Cal


Follow-Up Study of 1988 Nursing Graduates. Volume XVIII, No. 8.  

ERIC Educational Resources Information Center

In 1989, a follow-up study of nursing program graduates was conducted at William Rainey Harper College (WRHC) to examine their employment patterns, further education plans, and evaluate particular aspects of their WRHC experience. Questionnaires were mailed to 105 nursing students who graduated in 1988. Results were compared with previous surveys…

Dincher, J.; Meltesen, Cal


Follow-Up Study of 1990 Nursing Graduates. Volume XX, No. 10.  

ERIC Educational Resources Information Center

In 1990, a follow-up study of nursing program graduates was conducted at William Rainey Harper College (WRHC) in Palatine, Illinois, to examine their employment patterns, further education plans, and evaluate particular aspects of their WRHC experience. All 98 nursing students who earned 48 credit hours in 1990 were mailed questionnaires 1 year…

Lucas, J.; Meltesen, C.


The Preschool Attention-Deficit/Hyperactivity Disorder Treatment Study (PATS) 6-Year Follow-Up  

ERIC Educational Resources Information Center

Objective: To describe the clinical course of attention-deficit/hyperactivity disorder (ADHD) symptom severity and diagnosis from ages 3 to 5 up to 9 to 12 years during a 6-year follow-up after the original Preschool ADHD Treatment Study (PATS). Method: A total of 207 participants (75% male) from the original PATS, assessed at baseline (mean age,…

Riddle, Mark A.; Yershova, Kseniya; Lazzaretto, Deborah; Paykina, Natalya; Yenokyan, Gayane; Greenhill, Laurence; Abikoff, Howard; Vitiello, Benedetto; Wigal, Tim; McCracken, James T.; Kollins, Scott H.; Murray, Desiree W.; Wigal, Sharon; Kastelic, Elizabeth; McGough, James J.; dosReis, Susan; Bauzo-Rosario, Audrey; Stehli, Annamarie; Posner, Kelly



Specific active immunotherapy in advanced renal cell carcinoma: A clinical longterm follow-up study  

Microsoft Academic Search

The results of a 15-year follow-up study on 127 patients with renal cell carcinoma treated with immunotheapy are presented. All patients were suffering from advanced renal cell carcinoma and were treated by palliative nephrectomy and specific active immunotherapy using polymerized autologous tumour tissue with adjuvant and supportive dietary measures. The longest survival time was 164 months. Of the patients nephrectomized

T. Tallberg; H. Tykkä



A Bilingual Follow-Up Study of a VEA Funded Community Project.  

ERIC Educational Resources Information Center

A follow-up study was conducted by Skyline College (SC) to determine the effectiveness of an "economically depressed area" project undertaken by the college in Spring 1979 to promote SC's programs among low income area residents and to provide information to this group on consumer-related issues and community service agencies. During the project,…

Ozsogomonyan, Ardas


Family Literacy Lasts. The NFER Follow-up Study of the Basic Skills Agency's Demonstration Programmes.  

ERIC Educational Resources Information Center

The benefits of family literacy programs for children were examined in a 1997 follow-up study in which 154 parents and 237 children who had participated in a family literacy demonstration program in 1994-1995 were interviewed along with the teachers of a subsample of the children and the demonstration program coordinators. The demonstration…

Brooks, Greg; Gorman, Tom; Harman, John; Hutchison, Dougal; Kinder, Kay; Moor, Helen; Wilkin, Anne


Follow-Up Study of 1992 Dental Hygiene Graduates. Volume XXII, No. 2.  

ERIC Educational Resources Information Center

In a continuing effort to measure the quality of their Dental Hygiene program, explore the need for changes, and substantiate the program's goals for accreditation standards, a follow-up study was conducted of the 1992 Dental Hygiene program graduates from William Rainey Harper College (WRHC) in Palatine, Illinois. Surveys were mailed to all 29…

Holt, Marianne; Lucas, John A.


Follow-Up Study of 1987 Dental Hygiene Graduates. Volume XVII, No. 2.  

ERIC Educational Resources Information Center

In 1988, a follow-up study was performed of the 1987 graduates of the Dental Hygiene program of William Rainey Harper College (WRHC), in Illinois, in order to determine the quality of the program and the need for changes, and to substantiate the program's goals for accreditation standards. A survey was mailed to all of the 1987 dental hygiene…

Holt, Marianne; Flaherty, Toni


Follow-Up Study of 1990 Dental Hygiene Graduates. Volume XX, No. 1.  

ERIC Educational Resources Information Center

In a continuing effort to measure the quality of their Dental Hygiene program, explore the need for changes, and substantiate the program's goals for accreditation standards, a follow-up study was conducted of the 1990 Dental Hygiene program graduates from William Rainey Harper (WRHC) College in Palatine, Illinois. A survey was mailed to all 30…

Holt, Marianne; Lucas, John A.


Follow-Up Study of 1993 Dental Hygiene Graduates. Volume XXII, Number 17, June 1994.  

ERIC Educational Resources Information Center

In an effort to evaluate the effectiveness of its dental hygiene program, William Rainey Harper College (WRHC), in Palatine, Illinois, conducted a follow-up study of its dental hygiene students. The survey instrument was mailed to all 31 1993 dental hygiene associate degree graduates, and a response rate of 97% (n=30) was attained. Results of the…

Holt, Marianne; Lucas, John A.


Follow-Up Study of 1989 Dental Hygiene Graduates. Volume XIX, No. 2.  

ERIC Educational Resources Information Center

In a continuing effort to measure the quality of their Dental Hygiene program, explore the need for changes, and substantiate the program's goals for accreditation standards, a follow-up study was conducted of the 1989 Dental Hygiene program graduates from William Rainey Harper College (WRHC). A survey was mailed to all 29 associate degree…

Holt, Marianne; Lucas, John A.


Follow-Up Study of 1988 Dental Hygiene Graduates. Volume XVII, No. 7.  

ERIC Educational Resources Information Center

In 1989, a follow-up study was conducted of the 1988 graduates of William Rainey Harper College's (WRHC's) Dental Hygiene program in order to measure the quality of the program, explore the need for changes, and substantiate the program's goals for accreditation standards. A survey was mailed to all 27 associate degree graduates, requesting…

Holt, Marianne; Flaherty, Toni


Follow-Up Study of 1991 Dental Hygiene Graduates. Volume XXI, No. 4.  

ERIC Educational Resources Information Center

In a continuing effort to measure the quality of their Dental Hygiene program, explore the need for changes, and substantiate the program's goals for accreditation standards, a follow-up study was conducted of the 1991 Dental Hygiene program graduates from William Rainey Harper College (WRHC) in Palatine, Illinois. Surveys were mailed to all 28…

Holt, Marianne; Lucas, John A.


Nursing Education Follow-Up Study--1974 R.Ns. a Year After Graduation.  

ERIC Educational Resources Information Center

A group of 41 registered nursing graduates of the 1974 class at Bakersfield College was surveyed in the summer of 1974 as part of a nursing education follow-up study. In the summer of 1975, the same group was surveyed again in order to compare the perceptions and aspirations reported by the graduates one year after graduation with those reported…

Scott, David C.


Reversible Autism among Congenitally Blind Children? A Controlled Follow-Up Study  

ERIC Educational Resources Information Center

Background: Atypical forms of autism may yield insights into the development and nature of the syndrome. Methods: We conducted a follow-up study of nine congenitally blind and seven sighted children who, eight years earlier, had satisfied formal diagnostic criteria for autism and had been included in groups matched for chronological age and verbal…

Hobson, R. Peter; Lee, Anthony



Career Program Completers, 1991-92: A Long-Term Follow-Up Study.  

ERIC Educational Resources Information Center

In summer 1996, a long-term follow-up study was conducted of 1991-92 graduates of career programs at Johnson County Community College (JCCC), in Kansas. Questionnaires were mailed to 646 graduates, certificate holders, and students who left JCCC with marketable skills to assess their satisfaction with their educational experiences and their…

Conklin, Karen A.


A Follow-Up Study on Teacher Evaluation in China: Historical Analysis and Latest Trends  

ERIC Educational Resources Information Center

This research study follows up on previous investigations of the ongoing curriculum reform in China and its repercussions (actual and potential) on the effectiveness of the teacher evaluation process there (Liu & Teddlie, 2004, 2005). With the full implementation of the new curriculum reform throughout the country, teacher evaluation is becoming…

Liu, Shujie; Teddlie, Charles



Infantile-Onset Diabetes Mellitus: A 1Year Follow-up Study  

Microsoft Academic Search

This study evaluates the clinical profiles and outcomes of children with infantile-onset diabetes mellitus (IODM) (onset at <1 year). Twelve infants with IODM presenting to our hospital from January 2003 to December 2007 are analyzed. All undergo thorough history, clinical examination, and investigations and are managed as per hospital-approved protocol and periodically followed up. Of 12 infants (3 boys and

Ramaswamy Ganesh; Ravindrakumar Arvindkumar; Thiruvengadam Vasanthi



Clinically diagnosed childhood asthma and follow-up of symptoms in a Swedish case control study  

Microsoft Academic Search

BACKGROUND: Childhood asthma has risen dramatically not only in the western societies and now forms a major and still increasing public health problem. The aims of this study were to follow up at the age of ten the patterns of asthma symptoms and associations among children with a clinically diagnosed asthma in a sizeable urban-rural community and to in compare

Eduardo Roel; Åshild Faresjö; Olle Zetterström; Erik Trell; Tomas Faresjö



Magnitude of end-stage renal disease in IDDM: A 35 year follow-up study  

Microsoft Academic Search

Magnitude of end-stage renal disease in IDDM: A 35 year follow-up study. Significant improvements were made during the last two decades in the treatment of IDDM patients. To assess the risk of ESRD in a population that was exposed to these improvements, we determined the cumulative incidence of ESRD in a cohort of 142 white patients who were aged less

Martin Krolewski; Paul W Eggers; James H Warram



Career Program Completers, 1993-94: A Long-Term Follow-up Study.  

ERIC Educational Resources Information Center

This long-term follow-up study, conducted in the summer of 1998 by Johnson County Community College (JCCC, Kansas) focused on graduates, certificate recipients, and students identified by career program administrators as leaving with marketable skills in 1993-94. Since first administering this type of survey in 1989, JCCC has gained a broader…

Conklin, Karen A.


Long-Term Follow-Up Study of 1995-96 Career Program Completers.  

ERIC Educational Resources Information Center

This document is a 2000 follow-up of the long-term progress of the Johnson County Community College (JCCC) Career Program. The study targeted 377 graduates, certificate recipients, and students from 1995-96 who had completed the JCCC Career Program. Of the 377, 124 surveys were returned by mail and 168 surveys were completed via telephone…

Conklin, Karen A.


Follow-Up Study: Opinions from 1977-78 Graduates and Former Full-Time Students.  

ERIC Educational Resources Information Center

A follow-up study of 1977-78 graduates and former full-time students at Mt. Hood Community College (MHCC) was conducted to gather comparative data on programs and services and to meet requirements of external agencies. A questionnaire, requesting information on educational and employment activities after completing work at MHCC, was mailed to 711…

Walleri, R. Dan


WHI and WHIMS follow-up and human studies of soy isoflavones  

Microsoft Academic Search

Recent follow-up analyses of the previous findings from the Women's Health Initiative and the Women's Health Initiative Memory Study confirmed some health benefits of estrogen- containing hormone therapy (HT) in women within 10 years from the onset of menopause. However, the potential risks associated with long-term administration of HT, such as breast cancer and stroke, remain a concern for therapy

Liqin Zhao; Roberta Diaz Brinton


Neurodevelopmental Outcomes of Early Brain Injury: A Follow-Up of 14 Case Studies.  

ERIC Educational Resources Information Center

This follow-up study examines the developmental patterns and status of 14 children with congenital or acquired brain injury. Children with congenital impairments exhibited greater progress than the acquired impairment group. Program variables that might account for the differential progress are discussed. (Author/JDD)

Bagnato, Stephen J.; Neisworth, John T.



Epilepsy With Myoclonic Absences With Early Onset: A Follow-Up Study  

Microsoft Academic Search

We studied six children (four girls and two boys) suffering from cryptogenic myoclonic absence seizures with early onset. The age at onset of the seizures ranged between 6 and 27.8 months (mean age ± SD: 18.5 ± 12.4 months). The neurologic evaluation was normal in all patients at the first hospital admission. After the diagnosis, we followed up all children

Alberto Verrotti; Rita Greco; Francesco Chiarelli; Sergio Domizio; Giuseppe Sabatino; Guido Morgese



School's Out: A Comprehensive Follow-Up Study on Parents' Perceptions of Their Child's School  

ERIC Educational Resources Information Center

This longitudinal study set out to examine the changes that took place in parents' evaluations of their child's school in the course of the child's complete 9-year-long compulsory education. Over the follow-up period, academically educated and vocationally educated mothers and fathers (N = 326) were asked to indicate their degree of satisfaction…

Raty, Hannu



Perspective Transformation over Time: A 2-Year Follow-up Study of HIV-Positive Adults.  

ERIC Educational Resources Information Center

A follow-up study of 14 of 18 HIV-positive adults showed that their perspective transformation had been maintained 2 years later. Their meaning schemes changed to include a future-oriented perspective, greater attention to self-care, and integration of their HIV-positive status into their self-definition. (SK)

Courtenay, Bradley C.; Merriam, Sharan; Reeves, Patricia; Baumgartner, Lisa



Workload and Stress in New Zealand Universities. A Follow Up to the 1994 Study.  

ERIC Educational Resources Information Center

This follow-up study surveyed members of the Association of University Staff of New Zealand concerning their workload and stress levels and compared findings to a similar survey conducted in 1994. Survey responses (n=1155) were analyzed in terms of employment status, work hours, salary, responsibilities, changes and their impact, stresses and…

Chalmers, Anna


Colorado Even Start Follow-Up Study: Trinidad State Junior College.  

ERIC Educational Resources Information Center

Even Start family literacy programs are integrated adult education, early childhood education, and parent support components intended to break the intergenerational cycle of poverty and low literacy. In Spring of 2002, a follow-up study of one Even Start project was conducted to assess the long-term effects of Even Start programming for families.…

Anderson, Beckie


A Follow-Up Study of the Oregon Project. Final Report.  

ERIC Educational Resources Information Center

In 1973 the Children's Services Division (Oregon State) initiated a project to reduce the backlog of children in indeterminate status by developing more Permanent alternative placements. This follow-up study evaluates the placements of foster children who returned to their parents, were adopted, or remained in foster care. A literature review…

Lahti, Janet; And Others


A Follow-Up Study of the Oregon Project: A Summary.  

ERIC Educational Resources Information Center

This follow-up study of a special demonstration project (Oregon, 1973) evaluates the placement of children in foster care by exploring the stability and quality of placements. The project included 509 children who were under 12 years of age, unlikely to return home, and adoptable. The following questions were investigated: (1) How does the…

Lahti, Janet; And Others


Augmented cross-sectional studies with abbreviated follow-up for estimating HIV incidence.  


Cross-sectional HIV incidence estimation based on a sensitive and less-sensitive test offers great advantages over the traditional cohort study. However, its use has been limited due to concerns about the false negative rate of the less-sensitive test, reflecting the phenomenon that some subjects may remain negative permanently on the less-sensitive test. Wang and Lagakos (2010, Biometrics 66, 864-874) propose an augmented cross-sectional design that provides one way to estimate the size of the infected population who remain negative permanently and subsequently incorporate this information in the cross-sectional incidence estimator. In an augmented cross-sectional study, subjects who test negative on the less-sensitive test in the cross-sectional survey are followed forward for transition into the nonrecent state, at which time they would test positive on the less-sensitive test. However, considerable uncertainty exists regarding the appropriate length of follow-up and the size of the infected population who remain nonreactive permanently to the less-sensitive test. In this article, we assess the impact of varying follow-up time on the resulting incidence estimators from an augmented cross-sectional study, evaluate the robustness of cross-sectional estimators to assumptions about the existence and the size of the subpopulation who will remain negative permanently, and propose a new estimator based on abbreviated follow-up time (AF). Compared to the original estimator from an augmented cross-sectional study, the AF estimator allows shorter follow-up time and does not require estimation of the mean window period, defined as the average time between detectability of HIV infection with the sensitive and less-sensitive tests. It is shown to perform well in a wide range of settings. We discuss when the AF estimator would be expected to perform well and offer design considerations for an augmented cross-sectional study with abbreviated follow-up. PMID:21668904

Claggett, B; Lagakos, S W; Wang, R



On the course of low back pain in general practice: a one year follow up study  

PubMed Central

OBJECTIVES—Knowledge on the clinical course of low back pain presented in general practice is poor. Preceding studies offer a fragmentary view only, whereas further knowledge is important to enable the assessment of the prognosis. The object of this study is to investigate the course of low back pain presented in general practice to enable the assessment of the prognosis.?METHODS—A one year follow up study on the clinical course of low back pain in consecutive cases receiving usual care in general practice. During a period of two years 15 general practitioners from Amsterdam and surrounding areas included consecutive patients with both chronic and recent onset low back pain. After the initial visit, each patient was monitored for a period of 12 months. The follow up consisted of monthly postal questionnaires on the course of the low back pain and the related disability.?RESULTS—A total of 443 of 605 patients identified were included in the follow up, which was fully completed by 269 patients. In general, patients with less serious low back pain participated less often or did not complete the follow up. At 12 weeks 35% and at the end of the follow up 10% of the population, respectively, still suffered from low back pain. Both the pain and the disability seemed to diminish quickly after the initial visit, and both seemed to stabilise at a lower level if the low back pain did not disappear completely. About three of four patients, whose pain disappeared before the end of the follow up, endured one or more relapses within a year. The median time to a relapse was about seven weeks, and its median duration about six weeks. Both the pain and the disability turned out to be less severe during relapses. The median time to recovery for patients whose low back pain developed more than seven weeks before the initial visit, was four weeks longer than for patients with more recently developed low back pain at the initial visit.?CONCLUSIONS—The clinical course of low back pain presented in general practice, for the most patients, clearly is less favourable than expected. It takes more than just a few weeks to recover, and relapses occur within a year in most cases. Fortunately, both the pain and the disability quickly diminish, even if the low back pain does not resolve within a few weeks.?? Keywords: backache; prognosis; follow up study; general practice

van den Hoogen, H. J M; Koes, B.; van Eijk, J. T. M; Bouter, L.; Deville, W.



Effects of art therapy with prison inmates: A follow-up study  

Microsoft Academic Search

A pilot study conducted to measure the effects of art therapy with prison inmates (Gussak, 2004) demonstrated marked improvement in mood. The results of this study encouraged a quantitative follow-up study the following year. This study used the Formal Elements Art Therapy Scale (FEATS) and the Beck Depression Inventory-Short Form (BDI-II) as pre and post-test assessments to assess the effects

David Gussak



Sudden Sensorineural Hearing Loss Increases the Risk of Stroke A 5Year Follow-Up Study  

Microsoft Academic Search

Background and Purpose—No previous study has investigated the incidence or risk of cerebrovascular diseases developing after the sudden sensorineural hearing loss (SSNHL). This study sets out to estimate the risk of stroke development among SSNHL patients during a 5e-year follow-up period after hospitalization for acute episodes of SSNHL. Methods—Our study design features a study cohort and a comparison cohort. The

Herng-Ching Lin; Pin-Zhir Chao; Hsin-Chien Lee



The 'fine structure' of nutrient dynamics in rivers: ten years of study using high-frequency monitoring  

NASA Astrophysics Data System (ADS)

A complete appraisal of material fluxes in flowing waters is really only possibly with high time resolution data synchronous with measurements of discharge. Defined by Kirchner et al. (2004; Hydrological Processes, 18/7) as the high-frequency wave of the future and with regard to disentangling signal noise from process pattern, this challenge has been met in terms of nutrient flux monitoring by automated bankside analysis. In Ireland over a ten-year period, time-series nutrient data collected on a sub-hourly basis in rivers have been used to distinguish fluxes from different catchment sources and pathways and to provide more certain temporal pictures of flux for the comparative definition of catchment nutrient dynamics. In catchments where nutrient fluxes are particularly high and exhibit a mix of extreme diffuse and point source influences, high time resolution data analysis indicates that there are no satisfactory statistical proxies for seasonal or annual flux predictions that use coarse datasets. Or at least exposes the limits of statistical approaches to catchment scale and hydrological response. This has profound implications for catchment monitoring programmes that rely on modelled relationships. However, using high resolution monitoring for long term assessments of catchment mitigation measures comes with further challenges. Sustaining continuous wet chemistry analysis at river stations is resource intensive in terms of capital, maintenance and quality assurance. Furthermore, big data capture requires investment in data management systems and analysis. These two institutional challenges are magnified when considering the extended time period required to identify the influences of land-based nutrient control measures on water based systems. Separating the 'climate signal' from the 'source signal' in river nutrient flux data is a major analysis challenge; more so when tackled with anything but higher resolution data. Nevertheless, there is scope to lower costs in bankside analysis through technology development, and the scientific advantages of these data are clear and exciting. When integrating its use with policy appraisal, it must be made clear that the advances in river process understanding from high resolution monitoring data capture come as a package with the ability to make more informed decisions through an investment in better information.

Jordan, Phil; Melland, Alice; Shore, Mairead; Mellander, Per-Erik; Shortle, Ger; Ryan, David; Crockford, Lucy; Macintosh, Katrina; Campbell, Julie; Arnscheidt, Joerg; Cassidy, Rachel



Longterm follow-up in European respiratory health studies - patterns and implications  

PubMed Central

Background Selection bias is a systematic error in epidemiologic studies that may seriously distort true measures of associations between exposure and disease. Observational studies are highly susceptible to selection bias, and researchers should therefore always examine to what extent selection bias may be present in their material and what characterizes the bias in their material. In the present study we examined long-term participation and consequences of loss to follow-up in the studies Respiratory Health in Northern Europe (RHINE), Italian centers of European Community Respiratory Health Survey (I-ECRHS), and the Italian Study on Asthma in Young Adults (ISAYA). Methods Logistic regression identified predictors for follow-up participation. Baseline prevalence of 9 respiratory symptoms (asthma attack, asthma medication, combined variable with asthma attack and/or asthma medication, wheeze, rhinitis, wheeze with dyspnea, wheeze without cold, waking with chest tightness, waking with dyspnea) and 9 exposure-outcome associations (predictors sex, age and smoking; outcomes wheeze, asthma and rhinitis) were compared between all baseline participants and long-term participants. Bias was measured as ratios of relative frequencies and ratios of odds ratios (ROR). Results Follow-up response rates after 10 years were 75% in RHINE, 64% in I-ECRHS and 53% in ISAYA. After 20 years of follow-up, response was 53% in RHINE and 49% in I-ECRHS. Female sex predicted long-term participation (in RHINE OR (95% CI) 1.30(1.22, 1.38); in I-ECRHS 1.29 (1.11, 1.50); and in ISAYA 1.42 (1.25, 1.61)), as did increasing age. Baseline prevalence of respiratory symptoms were lower among long-term participants (relative deviations compared to total baseline population 0-15% (RHINE), 0-48% (I-ECRHS), 3-20% (ISAYA)), except rhinitis which had a slightly higher prevalence. Most exposure-outcome associations did not differ between long-term participants and all baseline participants, except lower OR for rhinitis among ISAYA long-term participating smokers (relative deviation 17% (smokers) and 44% (10–20 pack years)). Conclusions We found comparable patterns of long-term participation and loss to follow-up in RHINE, I-ECRHS and ISAYA. Baseline prevalence estimates for long-term participants were slightly lower than for the total baseline population, while exposure-outcome associations were mainly unchanged by loss to follow-up.



Delirium in elderly home-treated patients: a prospective study with 6-month follow-up  

Microsoft Academic Search

Delirium usually occurs during hospitalisation. The aims of this study were to evaluate the incidence of delirium in “hospital-at-home”\\u000a compared to a traditional hospital ward and to assess mortality, hospital readmissions and institutionalisation rates at 6-month\\u000a follow-up in elderly patients with intermediate\\/high risk for delirium at baseline according to the criteria of Inouye. We\\u000a performed a prospective, non-randomised, observational study

Gianluca Isaia; Marco A. Astengo; Vittoria Tibaldi; Mauro Zanocchi; Benedetta Bardelli; Rossella Obialero; Alessandra Tizzani; Mario Bo; Corrado Moiraghi; Mario Molaschi; Nicoletta Aimonino Ricauda



Replication of genetic linkage by follow-up of previously studied pedigrees  

SciTech Connect

Independent replication of linkage in previously studied pedigrees is desirable when genetic heterogeneity is suspected or when the illness is very rare. When the likelihood of the new data in this type of replication study is computed as conditional on the previously reported linkage results, it can be considered independent. The authors describe a simulation method using the SLINK program in which the initial data are fixed and newly genotyped individuals are simulated under [theta] = .01 and [theta] = .50. These give appropriate lod score criteria for rejection and acceptance of linkage in the follow-up study, which take into account the original marker genotypes in the data. An estimate of the power to detect linkage in the follow-up data is also generated. 13 refs., 1 fig., 1 tab.

Gershon, E.S.; Goldin, L.R. (National Institute of Mental Health, Bethesda, MD (United States))



Appalachian coal miner mortality study: a 14-year follow-up  

SciTech Connect

From 1963 to 1965, the U.S. Public Health Service examined 3,726 underground Appalachian bituminous coal miners who were living in 1962. Their vital status was verified on January 1, 1973 (10 years of follow-up) and again on January 1, 1976 (14 years of follow-up). Mortality was studied after 10 years and results were published by Ortmeyer (1974) and Costello (1974, 1975). The results of a study of the mortality after 14 years are the subject of this report. The cause of death was determined from the underlying cause recorded on the death certificate. Death from all causes, ischemic heart disease, non-malignant respiratory disease (NMRD), cancer of the trachea, bronchus, and lung, digestive cancer, and accidents were studied.

Amandus, H.



Slater revisited: 6 year follow up study of patients with medically unexplained motor symptoms  

PubMed Central

Objective: To investigate psychiatric and neurological morbidity, diagnostic stability, and indicators of prognosis in patients previously identified as having medically unexplained motor symptoms. Design: Follow up study. Setting: National Hospital for Neurology and Neurosurgery, London—a secondary and tertiary referral hospital for neurological disorders. Subjects: 73 patients with medically unexplained motor symptoms admitted consecutively in 1989-91. 35 (48%) patients had absence of motor function (for example, hemiplegia) and 38 (52%) had abnormal motor activity (for example, tremor, dystonia, or ataxia). Main outcome measures: Neurological clinical diagnosis at face to face reassessment by a neurologist and a psychiatric diagnosis after a standardised assessment interview—the schedule for affective disorders and schizophrenia—conducted by a psychiatrist. Results: Good follow up data were available for 64 subjects (88%). Only three subjects had new organic neurological disorders at follow up that fully or partly explained their previous symptoms. 44/59 (75%) subjects had had psychiatric disorders; in 33 (75%) patients, the psychiatric diagnosis coincided with their unexplained motor symptoms. 31/59 (45%) patients had a personality disorder. Three subjects had developed new psychiatric illnesses at follow up, but in only one did the diagnosis account for the previous motor symptoms. Resolution of physical symptoms was associated with short length of symptoms, comorbid psychiatric disorder, and a change in marital status during follow up. Conclusions: Unlike Slater’s study of 1965, a low incidence of physical or psychiatric diagnoses which explained these patients’ symptoms or disability was found. However, a high level of psychiatric comorbidity existed. Key messages Motor symptoms that remain unexplained medically despite thorough investigation are a common clinical problem, but the emergence of a subsequent organic explanation for these symptoms is rare The prevalence of coexistent affective and anxiety disorders is high and many patients also have a personality disorder Patients with a shorter duration of symptoms and coexistent anxiety or depression are likely to do better at follow up Reinvestigation of these patients is both expensive and potentially dangerous and should be avoided where no clear clinical indication exists

Crimlisk, Helen L; Bhatia, Kailash; Cope, Helen; David, Anthony; Marsden, C David; Ron, Maria A



Proliferative retinopathy predicts nephropathy: a 25-year follow-up study of type 1 diabetic patients  

Microsoft Academic Search

We wanted to examine proliferative retinopathy as a marker of incident nephropathy in a 25-year follow-up study of a population-based\\u000a cohort of Danish type 1 diabetic patients and to examine cross-sectional associations between nephropathy and retinopathy\\u000a in long-term surviving patients of the same cohort. All type 1 diabetic patients from Fyn County, Denmark, were identified\\u000a as of 1 July 1973.

Charlotte Karlberg; Christine Falk; Anders Green; Anne Katrin Sjølie; Jakob Grauslund


A Follow-Up Study of Girls With Gender Identity Disorder  

Microsoft Academic Search

This study provided information on the natural histories of 25 girls with gender identity disorder (GID). Standardized assessment data in childhood (mean age, 8.88 years; range, 3–12 years) and at follow-up (mean age, 23.24 years; range, 15–36 years) were used to evaluate gender identity and sexual orientation. At the assessment in childhood, 60% of the girls met the Diagnostic and

Kelley D. Drummond; Susan J. Bradley; Michele Peterson-Badali; Kenneth J. Zucker



A Follow-up Study of Men Exposed to Cadmium Oxide Fume  

Microsoft Academic Search

The results of a follow-up study of 100 men first examined in 1953 after exposure to cadmium oxide fume are presented and discussed.In 1953 there were 19 cases of chronic cadmium poisoning amongst these men. Twenty-four new cases are now described. The first signs of chronic cadmium poisoning could be seen after a latent interval after exposure had ended. Respiratory

J. A. Bonnell; G. Kazantzis; E. King



Predictors of weight change in men: Results from The Health Professionals Follow-Up Study  

Microsoft Academic Search

OBJECTIVE: Since the prevalence of adult obesity is increasing in the United States, we examined the effect of changing common habits (exercise, TV viewing, smoking and eating habits) on four year change in body weight.DESIGN: A prospective cohort study of US male health professionals with follow-up from 1988–1992. Participants were 19 478 men aged 40–75 in 1986, who were free

EH Coakley; EB Rimm; G Colditz; I Kawachi; W Willett



Adamantinoma of Long Bones: A Long-term Follow-up Study of 11 Cases  

Microsoft Academic Search

The aim of this study was to evaluate the clinicopathological features and prognostic significances of 11 histologically proven\\u000a adamantinoma cases based on an average 12,7 year long follow-up. The male: female ratio was 8:3, aged between 4 and 80 years\\u000a (mean 29,3 years). The initial diagnosis at referral was other than adamantinoma in six patients (fibrous dysplasia, carcinoma\\u000a metastasis, osteofibrous dysplasia, bone cyst,

Miklós Szendr?i; Imre Antal; Gabriella Arató



Shaken baby syndrome in Switzerland: results of a prospective follow-up study, 2002–2007  

Microsoft Academic Search

Since the incidence of shaken baby syndrome in Switzerland was not known, we conducted a nationwide prospective follow-up\\u000a study for a 5-year period (from 2002 to 2007). The data were collected through the Swiss Pediatric Surveillance Unit. Inclusion\\u000a criteria were the presence, in a child ?6 years of age, of 1) more than or equal to two clinical symptoms (altered consciousness,

Manuela Fanconi; Ulrich Lips



Vagus nerve stimulation in patients with catastrophic childhood epilepsy, a 2-year follow-up study  

Microsoft Academic Search

Purpose: To establish the long-term efficacy and tolerability of vagus nerve stimulation (VNS) in children with a Lennox-like syndrome. Method: This study was a longitudinal observational prospective cohort analysis. Baseline: 6 months. Follow-up: 24 months. Screening (baseline and every 6 months): MRI (baseline only), EEG, neuropsychological evaluation, ECG and blood sampling for antiepileptic drug levels. Nineteen children are included. Results:

H. J. M. Majoie; M. W. Berfelo; A. P. Aldenkamp; W. O. Renier; A. G. H. Kessels



Collapsing glomerulopathy in HIV and non-HIV patients: A clinicopathological and follow-up study  

Microsoft Academic Search

Collapsing glomerulopathy in HIV and non-HIV patients: A clinicopathological and follow-up study.BackgroundCollapsing glomerulopathy (CG) is a pattern of renal injury that is seen in association with HIV infection and that is increasingly recognized in non-HIV patients.MethodsA review of native kidney biopsies with CG that were diagnosed between 1979 and 1997 in 18 HIV and 42 non-HIV patients is provided.ResultsHIV and

Arvydas Laurinavicius; Shelley Hurwitz; Helmut G. Rennke



Metabolic Syndrome and Cognitive Function: A Population-Based Follow-Up Study in Elderly Women  

Microsoft Academic Search

Objective: To test the hypothesis that metabolic syndrome predicts cognitive impairment, and to examine the association of single metabolic risk factors with cognitive functioning. Methods: Weperformed a 12-year follow-up study in a population-based sample of 101 women aged 60–70 years at baseline. Metabolic syndrome wasdefined by the National Cholesterol Education Program criteria (?3 out of 5 risk factors). Global cognitive

Pirjo Komulainen; Timo A. Lakka; Miia Kivipelto; Maija Hassinen; Eeva-Liisa Helkala; Irja Haapala; Aulikki Nissinen; Rainer Rauramaa



Lifetime and six-month prevalence of mental disorders in the Munich follow-up study  

Microsoft Academic Search

Summary The Lifetime and 6 month DSM-III prevalence rates of mental disorders from an adult general population sample of former West Germany are reported. The most frequent mental disorders (lifetime) from the Munich Follow-up Study were anxiety disorders (13.87%), followed by substance (13.51%) and affective (12.90%) disorders. Within anxiety disorders, simple and social phobia (8.01%) were the most common, followed

Hans-Ulrich Wittchen; Cecilia Ahmoi Essau; Detlev von Zerssen; Jiirgen-Christian Krieg; Michael Zaudig



13- cis -retinoic acid in conglobate acne. A follow-up study of 14 trial centers  

Microsoft Academic Search

A follow-up was done on the patients of the German multicenter study with severe conglobate acne who had been treated with different dosages of 13-cis-retinoic acid. Eighty-seven patients were monitored from 12 to 21 months. Optimal long-term therapeutic effects were obtained with an initial dose of 1.0 mg\\/kg body weight, for 3 months, followed by another 3-month-treatment period with 0.2

R. Hennes; A. Mack; H. Schell; H. J. Vogt



The depressine Syndrome: a follow-up study of 130 professionals working overseas.  


A four-year follow-up of professional personnel who had been working overseas indicates that the depressive syndrome was the most common diagnosable psychiatric illness in this population. The study also shows that in this content the syndrome had a good prognosis. It therefore seems reasonable not to exclude persons with diagnosable depression from assignment abroad but, rather, to identify the syndrome and recommend necessary treatment. PMID:1124808

King, L J



Accessibility and Agency Website Design: Stumbling Backwards? A Follow-Up Study  

Microsoft Academic Search

This follow-up longitudinal study examined 86 social service agency websites that were previously examined in 2000. The websites were examined on dimensions of the language, readability, and disability access over a 10-year period. Data were gathered in 2000, 2005, and 2010. The results indicate that agencies are not creating websites that are user-friendly for diverse populations. This is due to

Kristin Friedmeyer-Trainor; Robert Vernon Director; Darlene Lynch



Meniscus allograft transplantation using posterior peripheral suture technique: a preliminary follow-up study  

Microsoft Academic Search

The aim of this study was to describe the indication, planning, technique, rehabilitation, and clinical results after cryopreserved allograft meniscus transplantation. Forty consecutive patients, 33 men and 7 women (mean, 37.3 years of age), were evaluated at 1-year follow-up post surgery. Symptoms, patient satisfaction, ROM (range of motion), surgical time, blood loss, and surgical history were evaluated. Thirty-eight (95%) patients

Kazumasa Fukushima; Nobuo Adachi; Joon Y. Lee; Vladimir Martinek; Mark Urquhart; Junnosuke Ryu; Freddie H. Fu



Routine vaccinations and child survival: follow up study in Guinea›Bissau, West Africa  

Microsoft Academic Search

Objective To examine the association between routine childhood vaccinations and survival among infants in Guinea›Bissau. Design Follow up study. Participants 15 351 women and their children born during 1990 and 1996. Setting Rural Guinea›Bissau. Main outcome measures Infant mortality over six months (between age 0›6 months and 7›13 months for BCG; diphtheria, tetanus, and pertussis; and polio vaccines and between

Ines Kristensen; Peter Aaby; Henrik Jensen


Developing COPD: a 25 year follow up study of the general population  

PubMed Central

Background Smokers are more prone to develop chronic obstructive pulmonary disease (COPD) than non?smokers, but this finding comes from studies spanning 10?years or less. The aim of this study was to determine the 25?year absolute risk of developing COPD in men and women from the general population. Methods As part of the Copenhagen City Heart Study, 8045 men and women aged 30–60?years with normal lung function at baseline were followed for 25?years. Lung function measurements were collected and mortality from COPD during the 25?year observation period was analysed. Results The percentage of men with normal lung function ranged from 96% of never smokers to 59% of continuous smokers; for women the proportions were 91% and 69%, respectively. The 25?year incidence of moderate and severe COPD was 20.7% and 3.6%, respectively, with no apparent difference between men and women. Smoking cessation, especially early in the follow up period, decreased the risk of developing COPD substantially compared with continuous smoking. During the follow up period there were 2912 deaths, 109 of which were from COPD. 92% of the COPD deaths occurred in subjects who were current smokers at the beginning of the follow up period. Conclusion The absolute risk of developing COPD among continuous smokers is at least 25%, which is larger than was previously estimated.

L?kke, A; Lange, P; Scharling, H; Fabricius, P; Vestbo, J



Infantile-onset diabetes mellitus: a 1-year follow-up study.  


This study evaluates the clinical profiles and outcomes of children with infantile-onset diabetes mellitus (IODM) (onset at <1 year). Twelve infants with IODM presenting to our hospital from January 2003 to December 2007 are analyzed. All undergo thorough history, clinical examination, and investigations and are managed as per hospital-approved protocol and periodically followed up. Of 12 infants (3 boys and 9 girls), 9 have a family history of DM. The median age at onset is 2.5 months. Six infants have features suggestive of Wolcott-Rallison syndrome (WRS), 4 infants have type 1 DM, and 1 infant each has Fanconi-Bickel syndrome and maturity-onset diabetes of young. None have pancreatic agenesis or calculi. Human leukocyte antigen (HLA) typing shows DQ3 and DR15 alleles predominating. Two children with WRS died; the rest are being followed up. The incidence of IODM is increasing, with multiple syndromic associations rather than a single perspective. PMID:18836058

Ganesh, Ramaswamy; Arvindkumar, Ravindrakumar; Vasanthi, Thiruvengadam




EPA Science Inventory

The purpose of this SOP is to define the coding strategy for the Follow Up Questionnaire. This questionnaire was developed for use in the Arizona NHEXAS project and the "Border" study. Household and individual follow-up data were combined in a single Follow-up Questionnaire data...


Long term follow up and retrospective study on 533 gastric cancer cases  

PubMed Central

Background Gastric cancer (GC) is the third leading cause of cancer death in China and the outcome of GC patients is poor. The aim of the research is to study the prognostic factors of gastric cancer patients who had curative intent or palliative resection, completed clinical database and follow-up. Methods This retrospective study analyzed 533 GC patients from three tertiary referral teaching hospitals from January 2004 to December 2010 who had curative intent or palliative resection, complete clinical database and follow-up information. The GC-specific overall survival (OS) status was determined by the Kaplan-Meier method, and univariate analysis was conducted to identify possible factors for survival. Multivariate analysis using the Cox proportional hazard model and a forward regression procedure was conducted to define independent prognostic factors. Results By the last follow-up, the median follow-up time of 533 GC patients was 38.6 mo (range 6.9-100.9 mo), and the median GC-specific OS was 25.3 mo (95% CI: 23.1-27.4 mo). The estimated 1-, 2-, 3- and 5-year GC-specific OS rates were 78.4%, 61.4%, 53.3% and 48.4%, respectively. Univariate analysis identified the following prognostic factors: hospital, age, gender, cancer site, surgery type, resection type, other organ resection, HIPEC, LN status, tumor invasion, distant metastases, TNM stage, postoperative SAE, systemic chemotherapy and IP chemotherapy. In multivariate analysis, seven factors were identified as independent prognostic factors for long term survival, including resection type, HIPEC, LN status, tumor invasion, distant metastases, postoperative SAE and systemic chemotherapy. Conclusions Resection type, HIPEC, postoperative SAE and systemic chemotherapy are four independent prognostic factors that could be intervened for GC patients for improving survival.



A 2-year follow-up study of discharged psychiatric patients with bipolar disorder.  


This study investigated medication compliance, disease recurrence and the recovery of social function in discharged psychiatric patients with bipolar disorder. A 2-year follow-up was conducted on all patients with bipolar disorder, who were hospitalized in our psychiatric department between June 2010 and May 2011. Risk factors for recurrence were analyzed based on a self-designed questionnaire. Of the 252 patients in the study, 210 had complete information (83.3%) for the 2-year follow-up: 170 cases of bipolar I disorder and 40 cases of bipolar II disorder. The 1-year and 2-year full-compliance rates were 41.0% and 35.7%, respectively. The 1-year and 2-year recurrence rates were 42.4% and 61.0%, respectively. Statistically significant differences in rates were found between the bipolar subtypes for 1-year full compliance, 1-year non-compliance, 2-year recurrence, and 2-year readmission. Logistic regression identified different sets of independent variables that were risk factors for recurrence, and protective factors for recurrence at 1 year and 2 years after hospital discharge. The results of the follow-up indicated that the situation of patients with bipolar disorder after discharge is not optimistic, because of high recurrence rates, high non-compliance rates and low recovery rates. Clinical and social experts should pay more attention to the situation. PMID:24794029

Li, Chunyang; Chen, Chao; Qiu, Bin; Yang, Guang



20-year prospective follow-up study of specialized treatment for adolescents who offended sexually.  


Most follow-up investigations of the effectiveness of specialized treatment for adolescents who have offended sexually have not included a comparison group. Furthermore, the average length of most previous studies is approximately 5 years. This investigation is a 10-year extension of our prospective, 10-year follow-up study of specialized treatment (Worling & Curwen, 2000). Recidivism data (criminal charges) were collected from a national database for 148 adolescents who had offended sexually. Adolescents were between 12 and 19 years of age (M = 15.5; SD = 1.5) at assessment, and the follow-up interval spanned from 12 to 20 years (M = 16.23; SD = 2.02). Relative to the comparison group (n = 90), adolescents who participated in specialized treatment (n = 58) were significantly less likely to receive subsequent charges for sexual, nonsexual violent, and nonviolent crimes. These data add to the growing body of research supporting the effectiveness of specialized treatment for individuals who have offended sexually. PMID:19937708

Worling, James R; Litteljohn, Ariel; Bookalam, David



Endoscopic stent therapy in patients with chronic pancreatitis: A 5-year follow-up study  

PubMed Central

AIM: This study analyzed clinical long-term outcomes after endoscopic therapy, including the incidence and treatment of relapse. METHODS: This study included 19 consecutive patients (12 male, 7 female, median age 54 years) with obstructive chronic pancreatitis who were admitted to the 2nd Medical Department of the Technical University of Munich. All patients presented severe chronic pancreatitis (stage III°) according to the Cambridge classification. The majority of the patients suffered intermittent pain attacks. 6 of 19 patients had strictures of the pancreatic duct; 13 of 19 patients had strictures and stones. The first endoscopic retrograde pancreatography (ERP) included an endoscopic sphincterotomy, dilatation of the pancreatic duct, and stent placement. The first control ERP was performed 4 wk after the initial intervention, and the subsequent control ERP was performed after 3 mo to re-evaluate the clinical and morphological conditions. Clinical follow-up was performed annually to document the course of pain and the management of relapse. The course of pain was assessed by a pain scale from 0 to 10. The date and choice of the therapeutic procedure were documented in case of relapse. RESULTS: Initial endoscopic intervention was successfully completed in 17 of 19 patients. All 17 patients reported partial or complete pain relief after endoscopic intervention. Endoscopic therapy failed in 2 patients. Both patients were excluded from further analysis. One failed patient underwent surgery, and the other patient was treated conservatively with pain medication. Seventeen of 19 patients were followed after the successful completion of endoscopic stent therapy. Three of 17 patients were lost to follow-up. One patient was not available for interviews after the 1st year of follow-up. Two patients died during the 3rd year of follow-up. In both patients chronic pancreatitis was excluded as the cause of death. One patient died of myocardial infarction, and one patient succumbed to pneumonia. All three patients were excluded from follow-up analysis. Follow-up was successfully completed in 14 of 17 patients. 4 patients at time point 3, 2 patients at time point 4, 3 patients at time point 5 and 2 patients at time point 6 and time point 7 used continuous pain medication after endoscopic therapy. No relapse occurred in 57% (8/14) of patients. All 8 patients exhibited significantly reduced or no pain complaints during the 5-year follow-up. Seven of 8 patients were completely pain free 5 years after endoscopic therapy. Only 1 patient reported continuous moderate pain. In contrast, 7 relapses occurred in 6 of the 14 patients. Two relapses were observed during the 1st year, 2 relapses occurred during the 2nd year, one relapse was observed during the 3rd year, one relapse occurred during the 4th year, and one relapse occurred during the 5th follow-up year. Four of these six patients received conservative treatment with endoscopic therapy or analgesics. Relapse was conservatively treated using repeated stent therapy in 2 patients. Analgesic treatment was successful in the other 2 patients. CONCLUSION: 57% of patients exhibited long-term benefits after endoscopic therapy. Therefore, endoscopic therapy should be the treatment of choice in patients being inoperable or refusing surgical treatment.

Weber, Andreas; Schneider, Jochen; Neu, Bruno; Meining, Alexander; Born, Peter; von Delius, Stefan; Bajbouj, Monther; Schmid, Roland M; Algul, Hana; Prinz, Christian



Incidental finding of monoclonal gammopathy in blood donors: a follow-up study  

PubMed Central

Background. The incidental finding of monoclonal immunoglobulin in the sera of healthy blood donors is a relatively frequent event and in such cases the subjects are commonly deferred permanently from donating blood. However, no follow-up studies of these cases have been published so far. Materials and methods. Since 2000, all regular blood donors at Trieste Blood Bank have undergone annual screening by serum protein electrophoresis. Cases presenting with monoclonal gammopathy between January 2000 and December 2008 were registered and follow-up was performed until December 2010. Results. Out of 8,197 regular blood donors, monoclonal gammopathy was detected in 104 subjects (1.3%). The median age at detection was 53 years, the median monoclonal protein concentration was 0.2 g/dL and the cumulative follow-up of these cases amounted to 763 person/years. In two cases asymptomatic multiple myeloma was diagnosed within 6 months of detection of the gammopathy and in 14 cases, the monoclonal gammopathy was transient. The remaining 88 cases were classified as having monoclonal gammopathy of undetermined significance (MGUS). Out of these, two events related to monoclonal gammopathy were observed during the follow up: one lymphoma and one light chain deposition nephropathy. Discussion. According to current prognostic staging systems, the majority of blood donors with monoclonal gammopathy were classified as having low-risk MGUS and had a very low incidence of lymphoproliferative diseases. Permanent deferral of blood donors with stable MGUS causes about a 1% loss of potential blood donations and it represents a “precautionary measure” that needs to be substantiated and validated.

La Raja, Massimo; Barcobello, Monica; Bet, Nicola; Dolfini, Paolo; Florean, Marina; Tomasella, Federica; De Angelis, Vincenzo; Mascaretti, Luca



Changes in leisure-time physical activity after transition to retirement: a follow-up study  

PubMed Central

Background Retirement is a major life change that is likely to affect lifestyles. The aim of this study was to examine changes in leisure-time physical activity of moderate and vigorous intensity among ageing employees facing transition to retirement over a follow-up of 5-7 years. Methods The baseline data were collected by questionnaire surveys in 2000-2002 among 40-60-year-old employees of the City of Helsinki. A follow-up survey was conducted among the baseline respondents in 2007 (n = 7332, response rate 83%). Those who were on disability retirement at the follow-up were distinguished from old-age retirees. Leisure-time physical activity was measured using similar questions in both surveys. Results Old-age retirees increased significantly their time spent in moderate-intensity physical activity: women 31 minutes per week and men 42 minutes per week on average. Such changes were not found among disability retirees or those remaining employed. There were no changes in vigorous activity. Leisure-time physical inactivity at follow-up was lower among old-age retirees compared with employees of nearly the same age. Adjustments made for potential baseline covariates had no effects on these findings. Conclusions Transition to old-age retirement was associated with an increase in moderate-intensity leisure-time physical activity and a decrease in the proportion of inactive. Encouraging people to leisure-time physical activity after retirement is worthwhile as the increase in free time brings new possibilities for it.



Patient relationship management: an overview and study of a follow-up system.  


Customer relationship management research is utilized to explain the need for a more patient-oriented support in patient care. This article presents a European study on how various hospital units of a single healthcare organization have utilized a patient relationship management system--in particular a patient treatment follow-up system--and how it affects patient care and the knowledge work performed by the medical staff. Eight physicians were interviewed at a university hospital on whether patient treatment was improved through a follow-up system that had been in use in the case organization for three years. The interviewees represented various hospital units, and all of them had used the system at their own unit. The results indicate that it is possible to improve patient care through more personalized treatment. The follow-up treatment system seems to be a tool to create and maintain better communication with the patients rather than just a technological solution. It may help better understand and analyze both individual patients and patient groups. For individual physicians it provides a way to reflect professional skills. The system was lacking in its support for one-to-one communication with patients. Nevertheless, the system is an example of patient relationship management which may help healthcare units to move towards a more patient-oriented care. PMID:19267028

Oinas-Kukkonen, Harri; Räisänen, Teppo; Hummastenniemi, Niko



Stability of alexithymia in late adolescence: Results of a 4-year follow-up study.  


The aim of the present study was to assess the stability of alexithymia in adolescents and the effects of parental factors and social support thereon. The sample comprised 315 late adolescents, of whom 259 were female and 56 male. At baseline, the mean age of the subjects was 19 years (range 17-21 years). The follow-up period was 4 years (2008-2012). The 20-item Toronto Alexithymia Scale (TAS-20) was used for the assessment of alexithymia both at baseline and follow-up. The Multidimensional Scale of Perceived Social Support (MSPSS) and the Parental Bonding Instrument (PBI) were used as measures at baseline. Regarding absolute stability, the changes in the TAS-20 total scores and two subscales (DIF and EOT) were statistically significant but the effect sizes for the changes were small (Cohen?s d 0.21-0.24). The test-retest correlations for the TAS-20 total and subscale scores were high (?=0.50-0.64, P<0.001), indicating relative stability. While several parental and social support variables were associated with alexithymia at baseline, low social support from friends was the only to predict higher alexithymia at follow-up. Alexithymia is a stable personality trait also in late adolescence. Low social support from friends is related to alexithymia in young adulthood. PMID:24953425

Karukivi, Max; Pölönen, Tuukka; Vahlberg, Tero; Saikkonen, Suvi; Saarijärvi, Simo



Ceramic-on-Ceramic Total Hip Arthroplasty: Minimum of Six-Year Follow-up Study  

PubMed Central

Background This study examines the clinical and radiologic results of ceramic-on-ceramic total hip arthroplasties with regard to wear, osteolysis, and fracture of the ceramic after a minimum follow-up of six years. Methods We evaluated the results of a consecutive series of 148 primary ceramic-on-ceramic total hip arthroplasties that had been performed between May 2001 and October 2005 in 142 patients. The mean age was 57.2 years (range, 23 to 81 years). The mean follow-up period was 7.8 years (range, 6.1 to 10.1 years). Preoperative diagnosis was avascular necrosis in 77 hips (52%), degenerative arthritis in 36 hips (24.3%), femur neck fracture in 18 hips (12.2%), rheumatoid arthritis in 15 hips (10.1%), and septic hip sequelae in 2 hips (1.4%). Clinical results were evaluated with the Harris hip score, and the presence of postoperative groin or thigh pain. Radiologic analysis was done with special attention in terms of wear, periprosthetic osteolysis, and ceramic failures. Results The mean Harris hip score improved from 58.3 (range, 10 to 73) to 92.5 (range, 79 to 100) on the latest follow-up evaluation. At final follow-up, groin pain was found in 4 hips (2.7%), and thigh pain was found in 6 hips (4.1%). Radiologically, all femoral stems demonstrated stable fixations without loosening. Radiolucent lines were observed around the stem in 25 hips (16.9%), and around the cup in 4 hips (2.7%). Endosteal new bone formation was observed around the stem in 95 hips (64.2%) and around the cup in 88 hips (59.5%). No osteolysis was observed around the stem and cup. There were 2 hips (1.4%) of inclination changes of acetabular cup, 2 hips (1.4%) of hip dislocation, 1 hip (0.7%) of ceramic head fracture, and 1 hip (0.7%) of squeaking. The Kaplan-Meier survival rate of the prostheses was 98.1% at postoperative 7.8 years. Conclusions The ceramic-on-ceramic total hip arthroplasty produced excellent clinical results and implant survival rates with no detectable osteolysis on a minimum six-year follow-up study. The ceramic-on-ceramic couplings could be a reasonable option of primary total hip arthroplasty for variable indications.

Choy, Won-Sik; Lee, Sang Ki; Bae, Kyoung Wan; Hwang, Yoon Sub; Park, Chang Kyu



Breast Cancer and the Environment on Long Island Follow-up Study

Dr. Marilie Gammon, of the University of North Carolina at Chapel Hill, and collaborating scientists in New York City, conducted a follow-up study on 1,098 women with breast cancer who participated in the parent population-based case-control study of Long Island women. The primary aims of the study were to determine whether environmental and other lifestyle factors influence breast cancer survival and overall survival among a population-based sample of Long Island women diagnosed with the disease.


Australian Aboriginal Birth Cohort study: follow-up processes at 20 years  

PubMed Central

Background In 1987, a prospective study of an Australian Aboriginal Birth Cohort was established focusing on the relationships of fetal and childhood growth with the risk of chronic adult disease. However as the study is being conducted in a highly marginalized population it is also an important resource for cross-sectional descriptive and analytical studies. The aim of this paper is to describe the processes of the third follow up which was conducted 20 years after recruitment at birth. Methods Progressive steps in a multiphase protocol were used for tracing, with modifications for the expected rural or urban location of the participants. Results Of the original 686 cohort participants recruited 68 were untraced and 27 were known to have died. Of the 591 available for examination 122 were not examined; 11 of these were refusals and the remainder were not seen for logistical reasons relating to inclement weather, mobility of participants and single participants living in very remote locations. Conclusion The high retention rate of this follow-up 20 years after birth recruitment is a testament to the development of successful multiphase protocols aimed at overcoming the challenges of tracing a cohort over a widespread remote area and also to the perseverance of the study personnel. We also interpret the high retention rate as a reflection of the good will of the wider Aboriginal community towards this study and that researchers interactions with the community were positive. The continued follow-up of this life course study now seems feasible and there are plans to trace and reexamine the cohort at age 25 years.



Zolpidem Use and the Risk of Injury: A Population-Based Follow-Up Study  

PubMed Central

Background While an association between zolpidem use and fracture and road accident was previously proposed, this study aimed to further explore the frequency and risk of a wide spectrum of injuries in subjects prescribed with zolpidem in Taiwan. Methods We identified 77,036 subjects who received Zolpidem treatment between 2005 and 2007. We randomly selected 77,036 comparison subjects who were frequency-matched based-on their demographic profiles. We individually tracked each subject for a 90-day period to identify those who subsequently suffered an injury. Cox proportional hazards regressions were performed to calculate the hazard ratio of injury between the two groups. Results The incidence rate of injury during the 90-day follow-up period for the total subjects was 18.11 (95% CI?=?17.69–18.54) per 100 person-years; this was 24.35 (95% CI?=?23.66–25.05) and 11.86 (95% CI?=?11.39–12.36) for the study and comparison cohort, respectively. After adjusting for demographic variables, the hazard ratio (HR) of injury during the 90-day follow-up period for study subjects was 1.83 (95% CI?=?1.73–1.94) that of comparison subjects. Additionally, compared to comparison subjects, the adjusted HR of injury during the 90-day follow-up period for study subjects who were prescribed Zolpidem for >30 days was as high as 2.17 (95% CI?=?2.05–2.32). The adjusted HR of injury to blood vessels for study subjects was particularly high when compared to comparison subjects (HR?=?6.34; 95% CI?=?1.37–29.38). Conclusions We found that patients prescribed with Zolpidem were at a higher risk for a wide range of injuries.

Lin, Ching-Chun; Wang, Li-Hsuan; Kang, Jiunn-Horng



Cannabinoids in multiple sclerosis (CAMS) study: safety and efficacy data for 12 months follow up  

PubMed Central

Objective: To test the effectiveness and long term safety of cannabinoids in multiple sclerosis (MS), in a follow up to the main Cannabinoids in Multiple Sclerosis (CAMS) study. Methods: In total, 630 patients with stable MS with muscle spasticity from 33 UK centres were randomised to receive oral ?9-tetrahydrocannabinol (?9-THC), cannabis extract, or placebo in the main 15 week CAMS study. The primary outcome was change in the Ashworth spasticity scale. Secondary outcomes were the Rivermead Mobility Index, timed 10 metre walk, UK Neurological Disability Score, postal Barthel Index, General Health Questionnaire-30, and a series of nine category rating scales. Following the main study, patients were invited to continue medication, double blinded, for up to12 months in the follow up study reported here. Results: Intention to treat analysis of data from the 80% of patients followed up for 12 months showed evidence of a small treatment effect on muscle spasticity as measured by change in Ashworth score from baseline to 12 months (?9-THC mean reduction 1·82 (n = 154, 95% confidence interval (CI) 0.53 to 3.12), cannabis extract 0.10 (n = 172, 95% CI –0.99 to 1.19), placebo –0.23 (n = 176, 95% CI –1.41 to 0.94); p = 0.04 unadjusted for ambulatory status and centre, p = 0.01 adjusted). There was suggestive evidence for treatment effects of ?9-THC on some aspects of disability. There were no major safety concerns. Overall, patients felt that these drugs were helpful in treating their disease. Conclusions: These data provide limited evidence for a longer term treatment effect of cannabinoids. A long term placebo controlled study is now needed to establish whether cannabinoids may have a role beyond symptom amelioration in MS.

Zajicek, J; Sanders, H; Wright, D; Vickery, P; Ingram, W; Reilly, S; Nunn, A; Teare, L; Fox, P; Thompson, A



Undifferentiated spondyloarthritis in a heterogeneous Brazilian population: an eight-year follow-up study.  


The aim of the present study was to describe the outcomes of Brazilian patients with undifferentiated spondyloarthritis during an eight-year follow-up period. Patients fulfilling the European Spondyloarthritis (SpA) Study Group Classification Criteria were enrolled. Forty patients were seen at baseline, and 36 participated in the follow-up study. Twenty-three (58 %) were female, and there were 24 (60 %) African Brazilians enrolled. HLA-B27 was positive in 18 (45 %) patients. At disease onset, the first presenting symptoms were pure peripheral manifestations in 26 (72.2 %) patients. After the study period, mixed disease (axial + peripheral) predominated occurring in 25 (69.4 %) patients. The Assessment of SpA International society (ASAS) classification criteria for axial SpA were fulfilled by 77 % of patients, and the ASAS criteria for peripheral SpA were fulfilled by 59 % of patients. After 2.5 years, 6 (16.7 %) of the 36 patients fulfilled the modified New York Criteria for ankylosing spondylitis and 1 (2.7 %) progressed to psoriatic arthritis. A total of 10 (27.8 %) patients progressed to definite SpA during the eight-year study period. Buttock pain (p = 0.006, OR 10.55; 95 % CI 2.00-65.90) and low-grade radiographic sacroiliitis (p = 0.025, OR = 11.50; 95 % CI 1.33-83.39) at baseline were associated with definite SpA. Thus, in this Brazilian cohort, which had a predominance of female African-Brazilian patients, prevalent peripheral onset symptoms were followed by a high frequency of axial manifestations during the follow-up period. Evidence of clinical or radiological sacroiliitis was associated with progression to definite SpA. PMID:23765202

da Cruz Lage, Ricardo; de Souza Bomtempo, Carlos Alexandre; Kakehasi, Adriana Maria; de Carvalho, Marco Antônio Parreiras



Science knowledge and efficacy beliefs among preservice elementary teachers: A follow-up study  

NASA Astrophysics Data System (ADS)

Slightly over two years ago aspects of knowledge and efficacy beliefs among preservice elementary teachers regarding science education were examined. Those results indicated a low level of science knowledge and a marked lack of confidence toward teaching science among prospective teachers. In the interim suggestions from that study have resulted in an increase in the number of required science courses that have been implemented in the teacher education program. The current, follow-up, study, found no increase in science content knowledge but did identify positive changes in efficacy beliefs. The results are discussed relative to Locus of Control theory.

Wenner, George



Functional Impairment in Body Dysmorphic Disorder: A Prospective, Follow-up Study  

PubMed Central

Cross sectional/retrospective studies indicate that individuals with body dysmorphic disorder (BDD) have markedly impaired psychosocial functioning. However, no study has prospectively examined functioning in BDD. In this study, which is to our knowledge the first prospective study of the course of BDD, psychosocial functioning was assessed at baseline and over 1 to 3 years (mean = 2.7 ± 0.9 years) of follow-up with the Global Assessment of Functioning Scale (GAF), Social and Occupational Functioning Scale (SOFAS), and LIFE-RIFT (Range of Impaired Functioning Tool). Psychosocial functioning was poor during the follow-up period. Functioning remained stably poor over time on the SOFAS and LIFE-RIFT, although there was a trend for a gradual and slight improvement on the GAF over time. The cumulative probability of attaining functional remission on the GAF (score >70 for at least 2 consecutive months) during the follow-up period was only 5.7%. On the SOFAS, the cumulative probability of attaining functional remission (score >70 for at least 2 consecutive months) was 10.6%. BDD severity significantly predicted functioning on the GAF (p=.0012), SOFAS (p=.0017), and LIFE-RIFT (p=.0015). A trend for a time-by-BDD severity interaction was found on the GAF (p=.033) but not the SOFAS or LIFE-RIFT. More delusional BDD symptoms also predicted poorer functioning on all measures, although this finding was no longer significant when controlling for BDD severity. Functioning was not predicted, however, by age, gender, BDD duration, or a personality disorder. In conclusion, psychosocial functioning was poor over time, and few subjects attained functional remission. Greater BDD severity predicted poorer functioning.

Phillips, Katharine A.; Quinn, Gene; Stout, Robert L.



A Prospective, 1-Year Follow-up Study of Postural Tachycardia Syndrome  

PubMed Central

Objective To prospectively evaluate patients who met standard criteria for postural tachycardia syndrome (POTS), at baseline and 1-year follow-up, using standard clinical and laboratory methods to assess autonomic function. Methods Fifty-eight patients met the study criteria (orthostatic symptoms and a heart rate increment of ?30 beats/min on head-up tilt) and completed 12 months of follow-up. All patients were enrolled and completed the study from January 16, 2006, through April 15, 2009. Patients underwent standardized autonomic testing, including head-up tilt, clinical assessment, and validated questionnaires designed to determine the severity of autonomic symptoms. Results Patients were predominantly young females (n=49, 84%), with 20 patients (34%) reporting an antecedent viral infection before onset of symptoms. More than one-third (37%) no longer fulfilled tilt criteria for POTS on follow-up, although heart rate increment on head-up tilt did not differ significantly at 1 year (33.8±15.1 beats/min) compared with baseline (37.8±14.6 beats/min) for the entire cohort. Orthostatic symptoms improved in most patients. Autonomic dysfunction was mild as defined by a Composite Autonomic Severity Score of 3 or less in 55 patients (95%) at baseline and 48 patients (92%) at 1 year. Conclusion To our knowledge, this is the first prospective study of the clinical outcomes of patients with POTS. Orthostatic symptoms improved in our patients, with more than one-third of patients no longer fulfilling tilt criteria for POTS, although the overall group change in heart rate increment was modest. Our data are in keeping with a relatively favorable prognosis in most patients with POTS.

Kimpinski, Kurt; Figueroa, Juan J.; Singer, Wolfgang; Sletten, David M.; Iodice, Valeria; Sandroni, Paola; Fischer, Philip R.; Opfer-Gehrking, Tonette L.; Gehrking, Jade A.; Low, Phillip A.



Ultrasonographically detected gallbladder polyps: A reason for concern? A seven-year follow-up study  

PubMed Central

Background The management of coincidental detected gallbladder polyps (GP) is still nebulous. There are few published data regarding their long-term growth. Objective of the present study was to investigate the prevalence and growth of gallbladder polyps in a survey of unselected subjects from the general population of a complete rural community. Methods A total of 2,415 subjects (1,261 women; 1,154 men) underwent ultrasound examination of the gallbladder, in November 1996 as part of a prospective study. Subjects in whom GP were detected at the initial survey underwent follow-up ultrasound examinations after 30 and 84 months. Results At the initial survey gallbladder polyps were detected in 34 subjects (1.4%; females: 1.1%, range 14 to 74 years; males: 1.7%, range 19 to 63 years). Median diameter was 5 ± 2.1 mm (range 2 to10 mm) at the initial survey, 5 mm ± 2.8 mm (range 2 to 12 mm) at 30 months and 4 ± 2.3 mm (range 2 to 9 mm) at 84 months. At the time of first follow-up no change in diameter was found in 81.0% (n = 17), reduction in diameter in 4.8% (n = 1) and increase in diameter in 14.3% (n = 3). At the time of second follow-up no increase in polyp diameter was found in 76.9% (n = 10) and reduction in diameter in 7.7% (n = 1). No evidence of malignant disease of the gallbladder was found. Conclusion Over a period of seven years little change was measured in the diameter of gallbladder polyps. There was no evidence of malignant disease of the gallbladder in any subject.

Kratzer, Wolfgang; Haenle, Mark M; Voegtle, Andrea; Mason, Richard A; Akinli, Atilla S; Hirschbuehl, Klaus; Schuler, Andreas; Kaechele, Volker



Back posture education in elementary schoolchildren: a 2-year follow-up study  

PubMed Central

Within the scope of primary prevention regarding back functioning in children, research on the stability of intervention effects is indispensable. Along this line, the transition from childhood to adolescence is an important phase to evaluate the potential stability of intervention effects because of the typically mechanical and psychological demands related to adolescence. The main aim of the current study was to investigate the effects of a back education program at 2-year follow-up, in youngsters aged 13–14 years, on back posture knowledge, fear-avoidance beliefs and self-reported pain. An additional purpose was to evaluate which aspects of postural behavior were integrated in youngsters’ lifestyles. At 2-year follow-up, the study sample included 94 secondary schoolchildren in the intervention group (mean age 13.3 ± 0.8 years) and 101 controls (mean age 13.2 ± 0.7 years). The back posture program that had been implemented for two school years consisted of back education and the stimulation of postural dynamism in the class through support and environmental changes. A questionnaire was completed comparable to the pretest, posttest and follow-up evaluations. The current study demonstrated at 2-year follow-up stability of the improved general (F = 1.590, ns) and specific (F = 0.049, ns) back posture knowledge in children who had received early back posture education. Back posture education did not result in increased fear-avoidance beliefs (F = 1.163, ns) or mounting back and/or neck pain reports (F = 0.001, ns). Based on self-reports for postural behavior, youngsters who had received the back posture program in the elementary school curriculum integrated crucial sitting and lifting principles conform to biomechanical favorable postural behavior. The steady intervention effects 2-year post-intervention demonstrated that intensive back posture education through the elementary school curriculum is effective till adolescence. Future research on the impact of early school-based back posture promotion in relation to the integration of back posture principles according to a biomechanical favorable lifestyle and back pain prevalence later in life is essential.

Geldhof, Elisabeth; De Bourdeaudhuij, Ilse; De Clercq, Dirk



Cognitive recovery instead of decline after acute encephalitis: a prospective follow up study  

PubMed Central

OBJECTIVE—Follow up of cognitive sequelae of acute encephalitis and estimation of the frequency of persisting dementia.?METHODS—Out of a series of 45 consecutive patients with acute encephalitis prospectively studied in 1990-95, 40 were screened for difficulty in everyday life using the Blessed dementia scale (BDS) 3.7 (1.4), mean (SD), years after onset. Eight patients had had herpes simplex encephalitis (HSVE), 16 some other identified aetiology, and in 21 the aetiology was unknown. All, except two patients with a non-herpetic encephalitis, were treated with acyclovir. All patients with disability in BDS (12/40), were invited to a neuropsychological reassessment, and the results of this assessment were compared with those of a similar assessment done after the acute stage. At follow up one patient could not complete the tests due to intractable epilepsy.?RESULTS—In six of 11 cases the symptoms causing disability were mainly psychiatric. Five patients (two with HSVE) had a pronounced memory impairment together with other cognitive deficits, indicating dementia (frequency of 12.8%). In eight of the 11 testable cases cognitive performance had improved over the years, in two cases a decline was found and one patient with severe deficits showed no change. Intractable epilepsy was found in four of 12cases.?CONCLUSION—Cognitive decline had taken place already at the acute stage, and further deterioration was uncommon. Considerable improvement occurred in most patients during follow up. Also in patients with HSVE treated with acyclovir the cognitive recovery was substantial and of a magnitude not expected based on previous literature. Intractable epilepsy contributed to the cognitive deterioration in some cases. Affective disorders also had a surprisingly important role for the long term outcome.??

Hokkanen, L.; Launes, J.



The MacArthur Violence Risk Assessment Study revisited: two views ten years after its initial publication.  


This article presents two views of the results of the MacArthur Violence Risk Assessment Study, which was conducted between 1992 and 1995 in order to ascertain the prevalence of community violence in a sample of people discharged from acute psychiatric facilities. The initial findings, which were published in 1998 in the Archives of General Psychiatry, have been cited by some advocates as proof that discharged psychiatric patients are not more dangerous than other persons in the general population. For the article presented here, Dr. Torrey and Mr. Stanley examined additional articles, book chapters, and a book about the MacArthur Study that have appeared since 1998 in order to ascertain whether the study's original conclusion should be modified and whether additional conclusions can be drawn from the subsequently published data. They present six points on which they disagree with the findings or fault the design of the MacArthur Study. After each point, Dr. Monahan, Dr. Steadman, and other authors of the MacArthur Study Group respond. PMID:18245156

Torrey, E Fuller; Stanley, Jonathan; Monahan, John; Steadman, Henry J



The Study Guides and Strategies Website ( Ten-Year Update and Current Applications  

ERIC Educational Resources Information Center

Over five years ago the author began his "TechTrends" column, then titled "E-Learning by Design," with a self interview. In that first column he interviewed himself on how he came to develop the Study Guides and Strategies (SGS) Website This educational public service and resource now contains 120 topics (200 English webpages) in…

Landsberger, Joe



A follow up study on the efficacy of metadoxine in the treatment of alcohol dependence  

PubMed Central

Background We carried out a three months follow-up study on the efficacy of metadoxine in a cohort of alcoholics admitted to the Alcohol misuse Long-term Treatment (ALT) Unit – University of Pisa (Italy). We analyzed the clinical data, psychometric tests and blood tests of 160 alcoholics on admission and after 3 months of treatment. We compared 58 pts treated with metadoxine (MET) with 102 pts who did not receive (NULL) any drug as an adjunct to the psycho-educational interventions provided by the ALT Unit. Results At follow-up, the patients in treatment with metadoxine showed a significant improvement in the rate of complete abstinence (44.8% vs. 21.6%; chi square: 8.45, df = 1, p < 0.0037). Furthermore, the number of drop-outs at three months of treatment was also significantly lower in the MET than in the NULL group (17% vs. 57%; chi square of 23.22, df = 1, p < 0.001). Conclusion Our findings support the use of metadoxine in the management of alcohol dependence. However, randomized clinical trials are necessary to confirm and replicate them. This study raises the importance of identifying new pharmacological compounds effective on the outcome of alcoholism in order to help patients to best adhere to treatment programs and to prevent the development of mental and physical complications due to chronic and heavy use of alcohol.

Guerrini, Irene; Gentili, Claudio; Nelli, Gloria; Guazzelli, Mario



Controlled trial of antituberculous chemotherapy in Crohn's disease: a five year follow up study  

PubMed Central

Background—It has been suggested that Mycobacterium paratuberculosis is the cause of Crohn's disease. In a previous report the immediate effect of two years treatment with antituberculous chemotherapy showed no clinical benefit. ?Aims—To assess both the immediate and longer term effect of treatment on the disease. ?Methods—Patients were followed for five years from their date of entry to the study. One hundred and thirty patients entered the initial study, and of these 111 (81%) were followed regularly. ?Results—Overall, there was no evidence of consistent benefit or disadvantage from antituberculous chemotherapy in any of the assessments made, including the number of acute relapses, surgical episodes, hospital admissions, disease activity, blood tests, or medication required for Crohn's disease during the follow up period. ?Conclusion—The absence of any benefit at the end of the initial two year trial period, and during the three year subsequent follow up, fails to support the hypothesis that mycobacteria play an important part in the pathogenesis of Crohn's disease, or that antituberculous chemotherapy may be of benefit. ?? Keywords: Crohn's disease; mycobacteria; antituberculus chemotherapy

Thomas, G; Swift, G; Green, J; Newcombe, R; Braniff-Mathews, C; Rhodes, J; Wilkinson, S; Strohmeyer, G; Kreuzpainter, G



Follow-up studies by peroral gastric biopsies and necropsy in vomiting dogs.  

PubMed Central

The results of follow-up studies in 139 vomiting dogs are presented. Follow-up studies were performed by biopsies in 34 dogs, by biopsies and necropsy in six dogs and by necropsy only in 99 dogs. The times between the first and the last series of biopsies varied from three to 1042 days and from one to 656 days between the first series of biopsies and necropsy. From the 55 dogs with gastritis in the first series of biopsies, 35 also showed gastritis in the following biopsies or at necropsy. These were mainly severe types of gastritis such as diffuse, hypertrophic or atrophic. Ten dogs with superficial gastritis showed no gastric changes at necropsy, two dogs had edema only and three dogs had gastric changes other than gastritis, such as multiple polyps. In general, carcinoma and lymphosarcoma were found in the biopsies as well as at necropsy, but in three cases of terminal carcinoma only gastritis had been diagnosed initially. In 35 dogs the first series of gastric biopsies showed no pathological changes, but in 22 of these dogs gastritis, ulceration, fibrosis, atrophy, gastric dilation with local necrosis, and perforation or lymphosarcoma of the submucosa were found in the second series of biopsies or at necropsy. Several dogs which did not have gastric changes at necropsy had enteritis or intestinal lymphosarcoma.

van der Gaag, I; Happe, R P



Recurrence of duodenal ulceration in patients on maintenance sucralfate. A 12-month follow-up study.  


A single-blind, 1-year follow-up study of 70 patients with recently healed duodenal ulcers was undertaken to assess the value of sucralfate (Ulsanic; Continental Ethicals) in preventing recurrence and to establish the lowest dose required to achieve this. Endoscopy was repeated on clinical relapse and routinely at 6 and 12 months. Fifty of the 70 patients were followed up for 12 months or to recurrence proved on endoscopy; the remaining 20 patients were excluded from analysis because of default or protocol violation. Endoscopic evidence of recurrence was found in 6 of 19 patients (32%) given sucralfate 1 g twice a day (group B), in 7 of 15 (47%) on sucralfate 1 g at night (group A), and in 13 of 16 controls (81%). The recurrence rates in groups A and B were significantly lower than in the control group (P less than 0,05 and P less than 0,005 respectively), and there was a significant gradient between the number of patients in remission at 12 months and the amount of medication (P less than 0,05). PMID:3838597

Marks, I N; Girdwood, A H



Conservative Treatment Protocol for Keratocystic Odontogenic Tumour: a Follow-up Study of 3 Cases  

PubMed Central

ABSTRACT Background The keratocystic odontogenic tumour is classified as a developmental cyst derived from the enamel organ or from the dental lamina. The treatment of keratocystic odontogenic tumour of the jaw remains controversial. The aim of this study was to report the outcome of our conservative treatment protocol for keratocystic odontogenic tumour. Methods Three patients with different complaints referred to Oral and Maxillofacial Surgery Clinic, Faculty of Dentistry, Selçuk University. Initial biopsy was carried out in all patients and keratocystic odontogenic tumours was diagnosed subsequent to histopathological examination. The patients with keratocystic odontogenic tumours were treated by enucleation followed by open packing. This conservative treatment protocol was selected because of existing young aged patients. The average follow-up duration of the cases was 2 years. Results Out of 3 cases, 2 lesions were present in mandible and 1 lesion in maxilla. There was no evidence of recurrence during follow-up. All the cases were monitored continuously with panoramic radiographs, computed tomography and clinical evaluations. Conclusions This conservative treatment protocol for keratocystic odontogenic tumours, based on enucleation followed by open packing would be a possible choice with a view of offering low recurrence rate and low morbidity rate particularly in young patients.

Yildirim, Gulsun; Ataoglu, Hanife; Kalayci, Abdullah; Kucuk, Korhan; Esen, Alparslan



Unilateral proptosis in thyroid eye disease with subsequent contralateral involvement: retrospective follow-up study  

PubMed Central

Background The purpose of this retrospective follow-up study is to evaluate the prevalence of patients with thyroid eye disease presenting with apparent unilateral proptosis and determine the occurrence of exophthalmos in contralateral non-proptotic eye over the time. Associated features with this event were evaluated. Methods A cohort of 655 consecutive patients affected by thyroid eye disease with a minimum follow-up of 10 years was reviewed. Exophthalmos was assessed by using both Hertel exophthalmometer and computed tomography (CT). The influence of age, gender, hormonal status and of different therapies such as corticosteroids, radiotherapy and surgical decompression on this disease progression was evaluated. Results A total of 89 patients (13.5%) (95% confidence interval [CI] 15%-10%) had clinical evidence of unilateral exophthalmos at the first visit. Among these, 13 patients (14%) (95% CI 22%-7%) developed subsequent contralateral exophthalmos. The increase of protrusion ranged from 2 to 7 mm (mean of 4.2). The time of onset varied from 6 months to 7 years (mean time: 29 months). Smoking status, young age and surgical decompression are significantly associated with development of contralateral proptosis (p< .05). Conclusions Asymmetric thyroid eye disease with the appearance of unilateral exophthalmos at the initial examination is a fairly frequent event, while subsequent contralateral proptosis occurs less commonly. However, physicians should be aware that young patients, particularly if smokers, undergoing orbital decompression in one eye may need further surgery on contralateral side over time.



Gallbladder Stones Following Ileal Resection for Gangrenous Intussusceptions: A Follow-up Study  

PubMed Central

Background: Intussusceptions are the most common causes of bowel obstruction in infancy and childhood in this environment they present late, resulting in gangrene of the intussusception consequently resection of the affected bowel and a limited or extended right hemicolectomy (RH) to establish bowel continuity. Aim: The aim of the following study is to follow-up these children that had a limited ileal resection for gangrenous intussusceptions and document the formation of stones in their gallbladders. Materials and Methods: A total of 14 patients who had limited ileal resection during infancy for gangrenous intussusceptions were matched with sixteen patients who had manual reduction for viable intussusceptions during infancy. Both groups had ultrasound scans of their gallbladders to document the formation of stones in their gallbladders. Results: No gallbladder stones were found in both groups, however, one male child that had a resection and a RH for a gangrenous intussusception at the age of 4 months and was seen at an interval of 72 months had a thickened gallbladder on ultrasonography, another child, a female child operated on at the age of 6 months and seen at an interval of 57 months also had a thickened gallbladder on ultrasonography. Conclusion: Although no stones were seen, we suggest a prolonged follow-up of these patients with either periodic ultrasonography of the their gallbladders or with the periodic estimation of their serum bile acids.

Osuoji, Roland Iheanyichukwu; Balogun, Babajide Olawale; Olofinlade, Olatunbosun Olabode



Epilepsy with myoclonic absences with early onset: a follow-up study.  


We studied six children (four girls and two boys) suffering from cryptogenic myoclonic absence seizures with early onset. The age at onset of the seizures ranged between 6 and 27.8 months (mean age +/- SD: 18.5+/-12.4 months). The neurologic evaluation was normal in all patients at the first hospital admission. After the diagnosis, we followed up all children for at least 5 years. At the end of follow-up, two of these patients (a girl and a boy) showed severe mental retardation, a high number (from one to three per day) of seizures, and persistent pathologic electroencephalograms. The other patients showed normal electroencephalograms: all of them were seizure free and without mental retardation. The two patients with mental retardation have been treated with polytherapy. In all other children we used valproate alone successfully. Our data suggest that myoclonic absence seizures with early onset can have a good long-term prognosis. Valproate is a useful anticonvulsant drug in these patients. Mental retardation is present only in patients with poor seizure control. PMID:10593554

Verrotti, A; Greco, R; Chiarelli, F; Domizio, S; Sabatino, G; Morgese, G



Risk Factors for Mortality in Hemodialysis Patients: Two-Year Follow-Up Study  

PubMed Central

Background. End-stage renal disease (ESRD) patients under hemodialysis (HD) have high mortality rate. Inflammation, dyslipidemia, disturbances in erythropoiesis, iron metabolism, endothelial function, and nutritional status have been reported in these patients. Our aim was to identify any significant association of death with these disturbances, by performing a two-year follow-up study. Methods and Results. A large set of data was obtained from 189 HD patients (55.0% male; 66.4 ± 13.9 years old), including hematological data, lipid profile, iron metabolism, nutritional, inflammatory, and endothelial (dys)function markers, and dialysis adequacy. Results. 35 patients (18.5%) died along the follow-up period. Our data showed that the type of vascular access, C-reactive protein (CRP), and triglycerides (TG) are significant predictors of death. The risk of death was higher in patients using central venous catheter (CVC) (Hazard ratio [HR] =3.03, 95% CI = 1.49–6.13), with higher CRP levels (fourth quartile), compared with those with lower levels (first quartile) (HR = 17.3, 95% CI = 2.40–124.9). Patients with higher TG levels (fourth quartile) presented a lower risk of death, compared with those with the lower TG levels (first quartile) (HR = 0.18, 95% CI = 0.05–0.58). Conclusions. The use of CVC, high CRP, and low TG values seem to be independent risk factors for mortality in HD patients.

do Sameiro-Faria, Maria; Costa, Elisio; Mendonca, Denisa; Teixeira, Laetitia; Rocha-Pereira, Petronila; Fernandes, Joao; Kohlova, Michaela; Reis, Flavio; Amado, Leonilde; Bronze-da-Rocha, Elsa; Miranda, Vasco; Quintanilha, Alexandre; Belo, Luis; Santos-Silva, Alice



What happens to quality in integrated homecare? A 15-year follow-up study  

PubMed Central

Objectives To explore the impact of structural integration on homecare quality. Methods A case study in an organisation comprising a before–after comparison with baseline and four follow-up measurements during 1994–2009, using interviews with clients (n=66–84) and postal inquiries to relatives (n=73–78) and staff (n=68–136). Results Despite the organisational reform involving extensive mergers of health and social care organisations and cuts in staff and service provision, homecare quality remained at almost the same level throughout the 15-year follow-up. According to the clients, it even slightly improved in some homecare areas. Conclusions The results show that despite the structural integration and cuts in staff and service provision, the quality of homecare remained at a good level. Assuming that the potential confounders did have inhibiting effects, the results suggest that structural integration had a positive impact on homecare quality. To obtain firmer evidence to support this tentative conclusion, further research with a randomised comparison design is needed.

Paljarvi, Soili; Rissanen, Sari; Sinkkonen, Sirkka; Paljarvi, Leo



Recurrence of keratocysts. A long-term follow-up study.  


The aim of the study was to investigate the recurrence rate of keratocysts based on a material with a follow-up of at least 5 years, and to evaluate the relationship between different features of these cysts and their recurrence. It was found that of 75 keratocysts with follow-up times ranging from 5 to 17 years (mean 8.3), 32 (43%) recurred. The cumulative recurrence rate of the 67 annually examined cysts increased from 3% after the 1st year following the operation to 37% after the 3rd year. Thereafter, no new recurrences were noted. Recurrence of keratocysts in patients with basal cell nevus syndrome occurred more frequently than that of patients without the syndrome. Keratocysts enucleated in one piece recurred significantly less often than cysts enucleated in several pieces. The recurrence rate of keratocysts with a clinically observable infection, with fistula or with a perforated bony wall was higher than that of keratocysts without these features. Recurrence was also found more frequently in cysts with multilocular radiographic appearance than in unilocular cysts. The size or the location of the keratocysts did not have an influence on the recurrence rate. PMID:3127485

Forssell, K; Forssell, H; Kahnberg, K E



Sensitivity of staphylococci from farm animals to antibacterial agents used for growth promotion and therapy. A ten year study.  


The following results were obtained during the period of 1970 to 1979-1980 in a study of 1040 Staphylococcus aureus strains in Belgium from cattle, poultry and pigs and 138 Staphylococcus hyicus strains from pigs, using the agar dilution technique and different penicillinase test methods: -- The incidence of penicillinase-positive strains increased in bovine and porcine S. aureus strains but decreased in poultry strains. From 1974 on more than 75% of S. aureus strains from cow udders produced penicillinase. -- The numbers of tetracycline-resistant strains steadily decreased during the period under investigation. -- Strains resistant to the macrolides and lincomycin were most frequent among S. hyicus and S. aureus strains from pigs isolated in 1973-1975. They were less numerous in 1979-1980. The inducible type of macrolide-resistance was found only among strains from poultry and cattle. In 1979-1980 strains resistant to lincomycin but susceptible to macrolide-antibiotics were detected. -- Two types of sensitivity to bacitracin were discovered: highly sensitive strains were frequent in cattle and rare in poultry. Intermediately sensitive strains dominated in poultry and pigs. These two groups of strains belonged to distinct chemotypes. Only one poultry strain was highly resistant to bacitracin. -- Number of neomycin-, sulphonamide- and chloramphenicol-resistant strains and strains resistant to the penicillinase-stable penicillins and cephalosporins were low and did not increase. -- Novobiocin resistance was only found among strains from broiler breeders and broilers. -- All strains tested were sensitive to the nitrofurans and related compounds (furazolidone, nitrovin), flavomycin, carbadox, trimethoprim, rifamycin and the virginiamycin combination. PMID:7337397

Devriese, L A



Recovery Potential of a Western Lowland Gorilla Population following a Major Ebola Outbreak: Results from a Ten Year Study  

PubMed Central

Investigating the recovery capacity of wildlife populations following demographic crashes is of great interest to ecologists and conservationists. Opportunities to study these aspects are rare due to the difficulty of monitoring populations both before and after a demographic crash. Ebola outbreaks in central Africa have killed up to 95% of the individuals in affected western lowland gorilla (Gorilla gorilla gorilla) populations. Assessing whether and how fast affected populations recover is essential for the conservation of this critically endangered taxon. The gorilla population visiting Lokoué forest clearing, Odzala-Kokoua National Park, Republic of the Congo, has been monitored before, two years after and six years after Ebola affected it in 2004. This allowed us to describe Ebola's short-term and long-term impacts on the structure of the population. The size of the population, which included around 380 gorillas before the Ebola outbreak, dropped to less than 40 individuals after the outbreak. It then remained stable for six years after the outbreak. However, the demographic structure of this small population has significantly changed. Although several solitary males have disappeared, the immigration of adult females, the formation of new breeding groups, and several birth events suggest that the population is showing potential to recover. During the outbreak, surviving adult and subadult females joined old solitary silverbacks. Those females were subsequently observed joining young silverbacks, forming new breeding groups where they later gave birth. Interestingly, some females were observed joining silverbacks that were unlikely to have sired their infant, but no infanticide was observed. The consequences of the Ebola outbreak on the population structure were different two years and six years after the outbreak. Therefore, our results could be used as demographic indicators to detect and date outbreaks that have happened in other, non-monitored gorilla populations.

Gatti, Sylvain; Levrero, Florence; Bigot, Elodie; Caillaud, Damien; Pierre, Jean-Sebastien; Menard, Nelly



Health Professionals Follow-up Study (HPFS): Prospective Studies of Diet and Cancer in Men and Women

The grant provides for continued follow-up for and research on the Health Professionals Follow-up Study (HPFS) of 51,529 men who completed an extensive dietary questionnaire first in 1986 and again in 1990, 1994,1998, 2002, 2006, and 2010. The program project grant also supports the food composition database and nutrient analysis system used by the Nurses' Health Study, Nurses' Health Study II, and many other studies.


Electroencephalographic features in dravet syndrome: five-year follow-up study in 22 patients.  


The aim of the study was to evaluate interictal electroencephalogram features in 22 patients with Dravet syndrome from the onset of the disease through the next 5 years. Electroencephalogram was abnormal in 5 patients (22.7%) at onset, and in 17 (77.3%) at the end of the study. Epileptiform abnormalities (focal, multifocal, or generalized) were seen in 6 patients at the onset and in 14 (27% vs 64%) at the end of the study. Photoparoxysmal response was present in 41% of patients at the end of follow-up. No statistical differences were found between mutated and nonmutated groups regarding evolution of background activity, interictal abnormalities, and presence of photoparoxysmal response. Electroencephalogram findings seemed to be age dependent, variable among different patients, and not influenced by the presence of sodium channel, voltage-gated, type I, alpha subunit (SCN1A) mutation. The lack of specific epileptiform abnormalities contributes to the difficulty of patients' management in Dravet syndrome. PMID:22019839

Specchio, Nicola; Balestri, Martina; Trivisano, Marina; Japaridze, Natia; Striano, Pasquale; Carotenuto, Antonio; Cappelletti, Simona; Specchio, Luigi M; Fusco, Lucia; Vigevano, Federico



Blackfoot disease in Taiwan: a 30-year follow-up study  

SciTech Connect

Blackfoot disease is an endemic peripheral vascular disease found among the inhabitants of a limited area on the southwest coast of Taiwan, where artesian well water with a high concentration of arsenic has been used for more than eighty years. The natural history of blackfoot disease, based on a prospective study of 1,300 patients, is presented. The overall male/female ratio was 1.5:1. Although the clinical onset was usually insidious, it may be quite sudden and almost always begins with numbness or coldness in one or more extremities, usually the feet. Ultimately, rest pain develops and progresses to gangrene. In this series, 68% of the patients underwent spontaneous or operative amputation, and the reamputation rate was 23.3%. Lower extremity involvement in blackfoot disease was observed in 97.7% of the cases. The average annual rate for major amputation was 3.81 per 100 patient-years. The factors influencing the prognosis, such as amputation in relation to age and disease onset, are analyzed. The case fatality rate was 66.5% during thirty years; 44% of these were cardiovascular deaths. The annual death rate was 4.84 per 100 patient-years. Other reported case fatality rates for vascular insufficiency are reviewed. A dose-response relationship between blackfoot disease and the duration of water intake was also noted. The survival rates after the onset of blackfoot disease were: five years, 76.0%; ten years, 59.5%; twenty years, 38.2%; thirty years, 28.6%. The 50% survival point was 13.5 years after onset of the disease.

Tseng, W.P.



[Study of the follow-up by the general practitioner of the children of separated parents].  


In Belgium, on 10 millions of inhabitants, there are more than 31.000 divorces per year and we estimate that 600.000 children are experiencing separation of their parents. The general practitioner (GP) have inevitably the responsability of the medical follow-up of some of these children. The possible professional implications related to these young patients, concerning the GP have never been the subject of a study so far. Consequently the aim of this research was to reveal what is happening in the daily practice of the family practitioner related with the children of separete parents. There were some hypothesis notably about particular working conditions for the GP in connection with possible consequences for these children and possible necessity of special professional attitudes. A qualitative research in focus group was organized with GPs in order to get an interaction between the participants and to go past the concepts supposed before the study. Therefore between September and December 04, 8 focus groups of 10-18 generalist practitioners were set up in Brussels and Mons. Each meeting was axed around couples separated for less than 3 years and children between 0 and 15 years. Finally, 120 GPs discussed about 242 cases of divorces from their practice. The debates totally typed word by word were analysed with assistance of the software QSR N5. The point of view of the GPs is: 1) A divorce affects the working conditions of the general practitioner, for example the parcelling out of the medical follow-up of the child and the fact " of being used" by the family. 2) The conflict between the parents after the separation increases the difficulties for the GP in his daily practice. 3) The parental's separation influences the choice of professional attitudes of the GP, notably vis-a-vis the conflict (for instance to try or not to try the conflict's management). 4) Mainly in conflict situation, parental divorce is a risk for the child; psychological or behavioural disorders, physical health problems, school difficulties, ... 5) Certain professional attitudes of the general practitioner can influence positively the evolution of these children, for example to speak to the two parents. 6) Some professional actions aggravate the situation of the these children, for instance to product certain official written documents (attestations, reports, certificats, ...) in a conflicts context. In conclusion, this study desmonstrates that parental separation affects the medical follow-up of the children by the GPs and that professional attitudes influences positively or negatively the child's evolution. For the first time, some negative consequences of the divorce on children are described in the first line. All this results must be confirmed by quantitative research work. PMID:17091892

Kacenelenbogen, N; Roland, M; Schetgen, M; Dusart, A F




EPA Science Inventory

The Food Follow-up Questionnaire data set provides information on the eating patterns and the food identification and preparation methods that occurred during the period the food sample was taken. The information is for 179 Food Follow-up Questionnaires for 179 households. In t...


A 6-year follow-up study of Cambodian refugee adolescents traumatized as children.  


Seventy-three percent of a sample of 46 Cambodian youth interviewed in 1984 and 1987 were reinterviewed in 1990 as part of a pretest for a multisite study of Cambodian refugee trauma now under way. An additional sample of convenience of 38 youth were also interviewed to determine reliability and validity of the diagnostic instruments chosen for the larger study. The DSM-III-R diagnosis of post-traumatic stress disorder (PTSD) was found to persist, but the symptoms appeared less intense over time. In contrast, the prevalence of depression dropped markedly since 1987. Subjects remained largely free of comorbid conditions. Diagnostic reliability and validity were satisfactory. The follow-up sample appeared to be functioning well despite their PTSD profiles. The findings are discussed in light of several current controversies surrounding the concept and measurement of PTSD. PMID:8444775

Sack, W H; Clarke, G; Him, C; Dickason, D; Goff, B; Lanham, K; Kinzie, J D



Case study of a spinal epidural capillary hemangioma: a 4-year postoperative follow-up.  


Study Design?Case study. Objectives?We report the case of a 58-year-old Caucasian man, who presented with a 4-month history of increasing low back pain and gait difficulty. Objective neurologic examination revealed a severe paraparetic symptomatology without any sphincter involvement. Methods?Spinal magnetic resonance imaging (MRI) showed an extradural mass formation situated dorsally at the level of thoracic vertebrae T2 to T4. Results?A laminectomy was performed with total removal of the mass; histology suggested a highly vascularized lesion with lobular architecture, which seems a very rare case, compatible with a capillary hemangioma. Conclusions?A careful follow-up for the next 4 years, including control MRIs every postoperative year, showed a very good neurologic condition of the patient and no recurrence on imaging findings. PMID:24494182

Seferi, Arsen; Alimehmeti, Ridvan; Vyshka, Gentian; Bushati, Teona; Petrela, Mentor



Recurrent spinal epidural metastases: a prospective study with a complete follow up  

PubMed Central

OBJECTIVES—Prospective studies with a complete follow up in patients with spinal epidural metastases (SEM) are rare, so little is known of the incidence and relevance of recurrent spinal epidural metastases (RSEM). This prospective study was undertaken as a part of a previously started and extended prospective study to determine the occurrence and details of RSEM.?METHODS—Patients with SEM of various primary malignancies were followed up until death. The diagnosis was confirmed after neurological examination by imaging studies visualising not only the clinically suspected level, but also as much of the spinal canal as possible.?RESULTS—Recurrent spinal epidural metastases (RSEM) occurred in 21 of the 103 patients (20%) after a median interval of 7 months and, after treatment, a second recurrence occurred in 11 patients (11%), a third recurrence in two patients (2%), and a sixth recurrence in one patient (1%). RSEM developed about as often at the initial level (55%) as at a different level (45%), did not occur more often in patients with initially multiple SEM, but, not surprisingly, occurred much more often in patients with longer survival. About one half of the patients surviving 2 years, and nearly all patients surviving 3 years or longer developed RSEM. Ambulatory state could be preserved in most patients, even after their second recurrence.?CONCLUSION—RSEM are common and even several episodes of RSEM in the same patient are not rare. Patients with SEM who survive long enough have a high risk of RSEM and prompt treatment of RSEM to maintain the ambulatory state of the patient is valuable.??

van der Sande, J J; Boogerd, W; Kroger, R; Kappelle, A



Asian-Specific total knee system: 5-14 year follow-up study  

PubMed Central

Background Knee size and body size differ in Asians compared with Caucasians. Nevertheless, many total knee arthroplasty (TKA) prostheses used worldwide are made for Western Caucasian subjects. As a result, an Asian's knee might not fit these prostheses. We studied the Flexible Nichidai Knee (FNK) system, a new model of TKA for Asian patients. The purpose of this report is to investigate the outcomes of this prosthesis retrospectively. Methods We investigated 1055 primary TKAs in 595 patients who underwent FNK for osteoarthritis (OA) in Japan and were followed for > 5 years. The knee score and function score were used for clinical evaluation. We examined the range of motion (ROM) preoperatively and at final follow-up and radiographic assessments. In addition, postoperative complications were investigated. A survivorship analysis was also conducted using two endpoints: revision for any reason and aseptic failure. Results 890 knees in 502 patients were available for study (follow-up rate of 96.0%). The mean follow-up term was 8.3 years (range, 5.0-14.1 years). The knee and function score significantly improved from 41.3 to 90.3 and from 39.1 to 76.2 points, respectively (p < 0.001). The mean ROM in FNK posterior cruciate retaining (CR) type and FNK posterior-stabilized (PS) type ameliorated significantly from 107.8° and 95.6° to 110.7° and 110.4°, respectively (p < 0.01). Ten knees underwent revision surgery (infection in 3 cases, instability in 2, loosening in 2, and non-union of femoral supracondylar fracture, severe pain, and recurrent hemarthrosis in 1 each). The survivorship rate was 99.4% (95% CI, 99.0-99.8) at 5 years (n = 952 patients at risk) and 96.2% (95% CI, 91.9-100) at 12.5 years (n = 49 patients at risk). Conclusion The FNK prosthesis for Asians achieved excellent mid- to long-term survivorship and clinical results.



Russian Military Capability in a Ten-Year Perspective: Problems and Trends in 2005. Summary and Conclusions from a Study for the Swedish Ministry of Defence.  

National Technical Information Service (NTIS)

The aim of the report is to analyze current trends of Russian development in order to draw conclusions on Russian military development in a ten-year perspective. The analysis is also put into the context of earlier ten-year assessments. In doing so, an ef...

J. Leijonhielm J. T. Knoph R. L. Larsson I. Oldberg W. Unge



Ongoing Colorectal Cancer Risk Despite Surveillance Colonoscopy: The Polyp Prevention Trial Continued Follow-up Study  

PubMed Central

Background Despite regular colonoscopy, interval colorectal cancer (CRC) may occur. Long-term studies examining CRC rates in patients with previous colonoscopy are lacking. Objective We examined the rate of interval CRC in the Polyp Prevention Trial-Continued Follow-up Study (PPT-CFS), an observational study of participants which began after the Polyp Prevention Trial (PPT) ended. Design Prospective Setting A national U.S. community-based polyp prevention trial Main Outcome Measurements Medical records of CRC were collected, reviewed, and abstracted in a standardized fashion. Results Among 2,079 PPT participants, 1,297 (62.4%) agreed to participate in the PPT-CFS. They were followed for a median of 6.2 years after 4.3 years of median follow up in the main PPT. Nine cases of CRC were diagnosed over 7,626 person years of observation (PYO) for an incidence rate of 1.2/1000 PYO. The ratio of CRCs observed compared to that expected by SEER was 0.64 (95% CI 0.28–1.06). Including all CRCs (N=22) since the beginning of the PPT trial, the observed compared to expected rate by SEER was 0.74 (95% CI 0.47–1.05). Of patients who developed CRC in the PPT-CFS, 78% had a history of an advanced adenoma compared to only 43% among patients who remained cancer-free (p=0.04). Limitations A relatively small number of interval cancers were detected. Conclusions Despite frequent colonoscopy during the PPT trial, in the years subsequent to the trial, there was a persistent ongoing risk for cancer. Subjects with a history of advanced adenoma are at increased risk for subsequent cancer and should be followed closely with continued surveillance.

Leung, Keith; Pinsky, Paul; Laiyemo, Adeyinka O.; Lanza, Elaine; Schatzkin, Arthur; Schoen, Robert E.



Nutritional Risk in Community-dwelling Older Men: The Manitoba Follow-up Study.  


Purpose: The role of nutrition in older men's health and successful aging has been inadequately studied. We examined the relationships among nutritional risk, self-rated health, and successful aging in community-dwelling Canadian older men. Methods: The surviving cohort of the Manitoba Follow-up Study (n=690, mean age = 86.8 years) were sent a self-administered nutrition survey in December 2007. The survey consisted of the Seniors in the Community: Risk Evaluation for Eating and Nutrition, version II (SCREEN II), a validated tool for assessing nutritional risk of cognitively intact community-living older adults, and questions about successful aging and health. Results: Of the 553 surveys returned (80% response), 522 with complete SCREEN II data were included in the analysis. Forty-four percent of respondents were at high nutritional risk, 24% were at moderate risk, and 32% were at low risk. Significant relationships were found between nutritional risk and self-rated health (P<0.0001) and successful aging (P=0.008), with greater nutritional risk associated with lower self-ratings of health and successful aging. Higher use of prescription medication was related to greater nutritional risk (P=0.004). Conclusions: Nutritional screening programs for community-dwelling older men are warranted as two-thirds of the study participants were at nutritional risk. Identifying older men at nutritional risk is a critical step in the process of nutritional assessment, and subsequent nutrition interventions and follow-up are required to prevent further health decline. PMID:24897014

Lengyel, Christina O; Tate, Robert B; Bayomi, Dennis J



Evaluation of Clinical Outcomes for Gastric Bypass Surgery: Results from a Comprehensive Follow-up Study  

Microsoft Academic Search

Background  Laparoscopic gastric bypass (LGB) surgery markedly increases percent excess weight loss (%EWL) and obesity-related co-morbidities.\\u000a However, poor study quality and minimal exploration of clinical, behavioral, and psychosocial mechanisms of weight loss have\\u000a characterized research to date.\\u000a \\u000a \\u000a \\u000a \\u000a Methods  We conducted a comprehensive assessment of n=100 LGB patients surveyed 2–3 years following surgery using standardized measures.\\u000a \\u000a \\u000a \\u000a \\u000a Results  Mean %EWL at follow-up was 59.1±17.2%. This

Garry Welch; Cheryl Wesolowski; Sofija Zagarins; Jay Kuhn; John Romanelli; Jane Garb; Nancy Allen



A follow-up study of the variations in the body composition of karate athletes.  


We monitored body composition variations in nine elite karateists during a 3-year period (T(1), T(2), T(3)). Arm circumference (AC) and six skinfolds were measured. Arm muscle circumference (AMC) and area (AMA) were then calculated. Fat mass (FM) was calculated using the Durnin-Womersley, Sloan-Weir (S-W), Katch-McArdle and Lohman equations. The only significant increase regarded the AC, AMC and AMA measurements between T(1) and T(2). The time course of the predicted FM amount using the different equations was the same. In particular, the S-W equation did not seem to reflect the modifications in the amount of FM as evidenced by the total sum of the six skinfolds. Our subjects were characterized by a substantial uniformity in body composition parameters measured in this 3-year follow-up study. PMID:14618455

Bertini, I; Pujia, A; Giampietro, M



A follow-up study of gastro-intestinal diseases related to bacteriologically substandard drinking water.  

PubMed Central

In a prospective follow-up study conducted in 52 French alpine villages, one weekly water sample was taken in each village provided with untreated ground water and analyzed as to the presence of four indicator bacteria: total plate count, total coliforms, thermotolerant (fecal) coliforms, and fecal streptococci. Cases of acute gastro-intestinal disease (AGID) occurring among 29,272 inhabitants were reported through physicians, pharmacists, and primary school teachers. A loglinear model identified fecal streptococcus (FS) as the best predictor; the presence of fecal coliforms enhanced the effect of FS. The total bacteria count and the total coliforms had no independent contributions. A threshold analysis suggested that any level of indicator bacteria above zero was associated with an excess of AGID.

Zmirou, D; Ferley, J P; Collin, J F; Charrel, M; Berlin, J



Clinical profile and follow-up of 51 pediatric neurocysticercosis cases: A study from Eastern India  

PubMed Central

Introduction: Our present observational study attempted to evaluate the clinical profiles, diagnosis, treatment and follow-up results of 51 pediatric neurocysticercosis patients over a mean duration of five years (from January 2006 to December 2010). Materials and Methods: Diagnosis was mainly based on clinical features, computed tomography (CT)/magnetic resonance imaging scan and exclusion of other causes. Patients with active, transitional cysts and seizure were treated with albendazole for 28 days, steroids and anticonvulsants. Results: A total of 38 patients completed this study. Mean age of the presentation was 8.47 ± 3.19 years 52.6% of the patients were female. Overall patients presented with generalized seizure in 55.3%, focal in 31.6%, headache ± vomiting in 63.2%, focal neurodeficit in 10.5% and combination of symptoms in 60.5% cases. Contrast CT brain showed a solitary lesion in 27 (71.1%) and multiple in the rest. At presentation lesions were transitional in 58.2%, inactive in 20% and mixed in 14.6%. After a mean of 2 years, seizure persisted in 9 (23.7%) and headache in 8 (21.1%) of whom six had normal electroencephalography (EEG) while one each showed focal slowing, generalized slowing and epileptiform discharges. During the follow-up, CT scan brain 44.7% lesions calcified, 31.6% disappeared, 10.5% regressed and the rest persisted. Conclusion: Solitary ring enhancing lesions (transitional stage) involving the parietal lobe was the commonest CT picture at presentation. Generalized tonic-clonic seizure was the most common type of seizure. Number of lesions, persistence of lesion, number of seizures, EEG abnormality at presentation were not found to be prognostically significant (P > 0.05).

Bhattacharjee, Shakya; Biswas, Prativa; Mondal, Tanushree



Prevalence of celiac disease in Germany: A prospective follow-up study  

PubMed Central

AIM: To determine the prevalence of celiac disease in a randomly selected population sample. METHODS: A total of 2157 subjects (1036 males; 1121 females) participating in a population-based cross-sectional study underwent laboratory testing for tissue transglutaminase and antibodies to immunoglobulin A, endomysium and antigliadin. In a second step, all subjects who had been examined serologically were surveyed using a questionnaire that included questions specific to celiac disease. Subjects with positive antibody titers and those with histories positive for celiac disease then underwent biopsy. At the first follow up, antibody titers were again determined in these subjects and subjects were questioned regarding symptoms specific for celiac disease and disorders associated with celiac disease. The second follow up consisted of a telephone interview with subjects positive for celiac disease. RESULTS: Antibody tests consistent with celiac disease were reported in eight subjects, corresponding to an overall prevalence of 1:270 (8/2157). The prevalence among women was 1:224 and 1:518 in men. Classical symptoms were observed in 62.5% of subjects. Atypical celiac disease was present in 25.0%, and transient celiac disease in 12.5%. False-negative test results were returned in three subjects. This yields a sensitivity and specificity of 62.5% and 50.0%, respectively, for tissue transglutaminase immunoglobulin-A antibody; of 62.5% and 71.4% respectively, for endomysium antibody; and of 62.5% and 71.4%, respectively, for antigliadin antibody. CONCLUSION: The prevalence rate in our collective lies within the middle tertile of comparable studies in Europe. The use of a single antibody test for screening purposes must be called into question.

Kratzer, Wolfgang; Kibele, Monika; Akinli, Atilla; Porzner, Marc; Boehm, Bernhard O; Koenig, Wolfgang; Oeztuerk, Suemeyra; Mason, Richard A; Mao, Ren; Haenle, Mark H



Determinants of Aortic Stiffness: 16-Year Follow-Up of the Whitehall II Study  

PubMed Central

Background Aortic stiffness is a strong predictor of cardiovascular disease endpoints. Cross-sectional studies have shown associations of various cardiovascular risk factors with aortic pulse wave velocity, a measure of aortic stiffness, but the long-term impact of these factors on aortic stiffness is unknown. Methods In 3,769 men and women from the Whitehall II cohort, a wide range of traditional and novel cardiovascular risk factors were determined at baseline (1991–1993) and aortic pulse wave velocity was measured at follow-up (2007–2009). The prospective associations between each baseline risk factor and aortic pulse wave velocity at follow-up were assessed through sex stratified linear regression analysis adjusted for relevant confounders. Missing data on baseline determinants were imputed using the Multivariate Imputation by Chained Equations. Results Among men, the strongest predictors were waist circumference, waist-hip ratio, heart rate and interleukin 1 receptor antagonist, and among women, adiponectin, triglycerides, pulse pressure and waist-hip ratio. The impact of 10 centimeter increase in waist circumference on aortic pulse wave velocity was twice as large for men compared with women (men: 0.40 m/s (95%-CI: 0.24;0.56); women: 0.17 m/s (95%-CI: ?0.01;0.35)), whereas the opposite was true for the impact of a two-fold increase in adiponectin (men: ?0.30 m/s (95%-CI: ?0.51;?0.10); women: 0.61 m/s (95%-CI: ?0.86;?0.35)). Conclusion In this large prospective study, central obesity was a strong predictor of aortic stiffness. Additionally, heart rate in men and adiponectin in women predicted aortic pulse wave velocity suggesting that strategies to prevent aortic stiffening should be focused differently by sex.

Brunner, Eric J.; Tabak, Adam G.; Shipley, Martin J.; Wilkinson, Ian B.; McEniery, Carmel M.; Roden, Michael; Herder, Christian; Kivimaki, Mika; Witte, Daniel R.



Tooth loss, periodontitis, and statins in a population-based follow-up study.  


Background: Statins, frequently prescribed in lipid-lowering therapies, seem to have additional beneficial effects on periodontitis and tooth loss. If this is true, then chronic treatment with statins should also result in diminished tooth loss as a long-term response. Methods: A 5-year population-based follow-up study of tooth loss was performed comparing participants treated with statins (n = 134) with those not on the drugs (Study of Health in Pomerania). Negative binomial regression models were used to analyze the count variable of the outcome, including risk factors for tooth loss and measures of cholesterol metabolism. Results: When adjusted for age and sex, statins were associated with reduced tooth loss during the follow-up period (incidence risk ratio [IRR] = 0.70, 95% confidence interval [CI] = 0.50 to 0.99, P = 0.04). When additionally adjusted for risk factors of periodontal breakdown, IRR was 0.72 (95% CI = 0.52 to 1.01). There was significant interaction with low-density lipoprotein cholesterol (LDL-c) at baseline. After stratification by LDL-c, statins were associated with reduced tooth loss, resulting in IRR = 0.89 (95% CI = 0.44 to 1.83) and 0.64 (95% CI = 0.43 to 0.95), P = 0.03, at LDL-c concentrations ?100 mg/dL and >100 mg/dL (2.58 mmol/L), respectively. The data also showed reduced tooth loss associated with the 5-year reduction in LDL-c levels on a mmol/L basis and independently of statins (IRR = 0.87, 95% CI = 0.80 to 0.96, P = 0.004). Conclusion: Long-term treatment with systemically administered statins may have the beneficial effect of protecting against tooth loss. PMID:24304227

Meisel, Peter; Kroemer, Heyo K; Nauck, Matthias; Holtfreter, Birte; Kocher, Thomas



Follow up study of children born to mothers resident in Seascale, West Cumbria (birth cohort).  

PubMed Central

Records on 1068 children who were born to mothers resident in Seascale Civil Parish during 1950-83 were studied. There was a large degree of mobility among the families, and nearly half of the children did not subsequently attend the main local school. Use of the National Health Service Central Register, however, enabled us to follow up the children's records regardless of place of residence. The excess of leukaemia among Seascale children first supported from the analysis of geographical areas is confirmed. There were five deaths from leukaemia identified to 30 June 1986 compared with 0.53 expected at national rates--a ratio of 9.36 (95% confidence interval 3.04 to 21.84). One of these deaths occurred after the child had left Seascale. There were four deaths from other cancers compared with 1.06 expected--a ratio of 3.76 (95% CI 1.02 to 9.63). In addition, three further cases of cancer, apart from the deaths, were reported compared with 1.19 expected since 1971--a ratio of 2.53 (95% CI 0.52 to 7.40). For other causes of death, including stillbirths and infant mortality, there was a reported deficit compared with national rates, some of which at least was to be expected on the basis of the social class composition of the population of Seascale. In view of the importance of this cohort of births continued follow up is planned, with the possibility of extending it to include births since 1983, and the methods available for this type of study will be examined further.

Gardner, M J; Hall, A J; Downes, S; Terrell, J D



Fractures of the femoral head: a long-term follow-up study.  


The femoral head fracture has become an increasingly frequent injury, usually sustained by individuals during high-energy trauma. Regardless of the type of treatment, long-term consequences, as avascular necrosis, post-traumatic arthritis, and heterotopic ossification, may complicate the clinical outcome leading to variable degree of disability. The aim of this study was to review the clinical and radiological long-term follow-up of patients with a fracture of the femoral head. Between January 1985 and January 2002, twenty-one patients with mean age 42.0 ± 15.9 years (range, 21-70 years) with a fracture of the femoral head were evaluated retrospectively. According to Pipkin's classification, there were four type I, nine type II, and eight type IV fractures. Functional outcomes were measured using the Merle d'Aubigné-Postel and Thompson-Epstein scoring scale. Heterotopic calcifications was graded according to the Brooker classification. All patients were followed up from 12 to 210 months, with an average of 81.19 ± 37.4 months. The average Merle d'Aubigné-Postel score was 12.9 ± 4.5. According to the Thompson-Epstein criteria, eight patients had excellent results, eight patients good, two patients fair, and three patients poor results. Overall, almost all (95. 2%) patients were determined to have radiographic criteria of post-traumatic arthritis (PA). Ten patients (47.6%) had a mild PA, seven patients (33.3%) had a moderate PA, and three patients (14.2%) had a severe PA. Open reduction and internal fixation of the fragments provided better results in comparison to excision. Although degenerative changes of the hip were observed in almost all patients, most severe case occurred in the excision group. PMID:22389008

Oransky, M; Martinelli, N; Sanzarello, I; Papapietro, N



What Affects Reintegration of Female Drug Users after Prison Release? Results of a European Follow-Up Study  

ERIC Educational Resources Information Center

The main objective of this follow-up study is to explore factors influencing the success or failure of women in reintegrating after their release from prison. Female drug users in five European cities were tracked after being released from prison. Out of 234 female prisoners contacted in prisons, 59 were included in the follow-up study. Structured…

Zurhold, Heike; Moskalewicz, Jacek; Sanclemente, Cristina; Schmied, Gabriele; Shewan, David; Verthein, Uwe



Education Longitudinal Study of 2002 (ELS:2002) Third Follow-up Data File Documentation. NCES 2014-364  

ERIC Educational Resources Information Center

This report provides guidance and documentation for users of the combined base-year to third follow-up data of the Education Longitudinal Study of 2002 (ELS:2002). ELS:2002 is sponsored by the National Center for Education Statistics (NCES) of the Institute of Education Sciences, U.S. Department of Education. The base-year and follow-up studies

Ingels, Steven J.; Pratt, Daniel J.; Alexander, Christopher P.; Jewell, Donna M.; Lauff, Erich; Mattox, Tiffany L.; Wilson, David



Results of the cementless Plasmacup in revision total hip arthroplasty: a retrospective study of 72 cases with an average follow-up of eight years  

PubMed Central

Background There are multiple revision implant systems currently available for socket revision in revision total hip arthroplasty. Up until now, not all of these systems have been followed up with regards to their long-term use as a revision implantation. For the first time, this study presents the hemispherical porous-coated socket Plasmacup SC, produced by Aesculap, Tuttlingen, Germany, and the clinical and radiological mid-term results of this revision cup implant. Methods Over a period of ten years the Plasmacup SC press-fit-cup was used as a revision implant in 72 consecutive aseptic cases which were included in this retrospective study. The mean follow-up period was 8 years. Bone graft transplantation was performed in 32% of all cases. In 90%, the cup was fixed with additional screws. The follow-up radiographs were analysed with regards to cup migration, osteointegration and osteolysis in the DeLee zones using a computer aided program taking the teardrop figure as a main point of reference. For clinical evaluation the Harris-Hip-Score and the WOMAC-Score were utilized. Results At the follow up examination, the mean Harris-Hip-Score was 83.5 points and the mean WOMAC-Score 34.7 points. 93% of all patients were satisfied with the result of the operation. No aseptic cup loosening could be observed and only one cup had to be removed due to infection. No significant longitudinal or transversal cup migration could be observed. Conclusion Aesculap's Plasmacup SC is suitable as a cementless cup revision implant. There is stable cup osteointegration, post press-fit implantation, even in the case of major acetabular bone defects.



Follow-Up Evaluation Studies and Procedures, College of Education, Bowling Green State University, Bowling Green, Ohio.  

ERIC Educational Resources Information Center

This document presents a summary of follow-up evaluation studies of basic and advanced education graduates, conducted by the Office of Educational Research and Services at Bowling Green State University (Ohio) over the last few years. (The university's evaluative follow-up endeavors have been closely tied to a needs assessment model, and a major…

Pigge, Fred L.


Asperger Syndrome and Autism: A Comparative Longitudinal Follow-Up Study More than 5 Years after Original Diagnosis  

ERIC Educational Resources Information Center

Prospective follow-up study of 70 males with Asperger syndrome (AS), and 70 males with autism more than 5 years after original diagnosis. Instruments used at follow-up included overall clinical assessment, the Diagnostic Interview for Social and Communication Disorders, Wechsler Intelligence Scales, Vineland Adaptive Behavior Scales, and Global…

Cederlund, Mats; Hagberg, Bibbi; Billstedt, Eva; Gillberg, I. Carina; Gillberg, Christopher



Pseudoexfoliation and Alzheimer's disease: a population-based 30-year follow-up study.  


Purpose:? To determine the effect of pseudoexfoliation (PEX) on the development of Alzheimer's disease (AD) in a population in which PEX is a common finding. The relationship between open-angle glaucoma (OAG) and AD was also studied. Methods:? Predictors of incident AD, including mixed and unspecified dementia, were analysed in a cohort of 679 residents 65-74?years of age, examined in a population survey in the municipality of Tierp, Sweden, 1984-1986. To expand the cohort, participants in other studies in Tierp were enrolled. In this way, the cohort embraced 1123 people, representing more than 15?700 person-years at risk. Medical records were reviewed to identify subjects diagnosed with dementia. Those with a follow-up time shorter than 2?years were excluded from the study. Results:? By the conclusion of the study, in December 2011, 174 new cases of AD, including mixed and unspecified dementia, had been detected, 41 of whom were affected by PEX at baseline. Higher age and female gender were the only predictors identified. No association between PEX and AD was found (hazard ratio 0.98; 95% confidence interval 0.69-1.40). Newly diagnosed OAG at baseline did not increase the risk (hazard ratio 1.09; 95% confidence interval 0.69-1.74). Conclusion:? Pseudoexfoliation is not a predictor of AD. No association was found between OAG and AD. PMID:23879292

Ekström, Curt; Kilander, Lena



Proximal femoral allograft-prosthesis composites in revision hip replacement: a 12-year follow-up study.  


We report the use of an allograft prosthetic composite for reconstruction of the skeletal defect in complex revision total hip replacement for severe proximal femoral bone loss. Between 1986 and 1999, 72 patients (20 men, 52 women) with a mean age of 59.9 years (38 to 78) underwent reconstruction using this technique. At a mean follow-up of 12 years (8 to 20) 57 patients were alive, 14 had died and one was lost to follow-up. Further revision was performed in 19 hips at a mean of 44.5 months (11 to 153) post-operatively. Causes of failure were aseptic loosening in four, allograft resorption in three, allograft nonunion in two, allograft fracture in four, fracture of the stem in one, and deep infection in five. The survivorship of the allograft-prosthesis composite at ten years was 69.0% (95% confidence interval 67.7 to 70.3) with 26 patients remaining at risk. Survivorship was statistically significantly affected by the severity of the pre-operative bone loss (Paprosky type IV; p = 0.019), the number of previous hip revisions exceeding two (p = 0.047), and the length of the allograft used (p = 0.005). PMID:20190304

Babis, G C; Sakellariou, V I; O'Connor, M I; Hanssen, A D; Sim, F H



Periods of Recovery in Deficit Syndrome Schizophrenia: A 20-Year Multi-follow-up Longitudinal Study  

PubMed Central

Periods of recovery were examined in patients with and without deficit syndrome schizophrenia. Fifty-six patients with schizophrenia were studied, 39 of whom were divided into deficit and nondeficit syndrome schizophrenia subtypes using a proxy method. We also studied 39 nonpsychotic depressive comparison patients. Patients were evaluated as part of the Chicago Follow-up Study, which prospectively examined patients at regular intervals over a 20-year period. Using standardized instruments, patients were evaluated for the deficit syndrome, global recovery, rehospitalization, social dysfunction, occupational disability, and symptom presentation. Recovery was examined at 6 time points measured at 2-, 4.5-, 7.5-, 10-, 15-, and 20-year postindex hospitalization. Cumulatively, over the 20-year period, 13% of patients classified as meeting criteria for the deficit syndrome showed 1 or more 1-year periods of global recovery, in comparison to 63% of nondeficit schizophrenia patients and 77% of depressed patient controls. Results indicate that the deficit syndrome represents a persistently impaired subsample of schizophrenia patients, with continuous social, occupational, and symptom impairment. In contrast, nondeficit syndrome schizophrenia patients showed at least some periods of remission or recovery, with the likelihood of these periods increasing as they became older. Findings provide further support for the validity of the deficit syndrome concept and suggest that deficit status is characterized by a more persistently impaired course of illness and particularly poor long-term prognosis.

Strauss, Gregory P.; Harrow, Martin; Grossman, Linda S.; Rosen, Cherise



Relationships in oocyte recipient couples - a Swedish national prospective follow-up study  

PubMed Central

Background The long-term effect of treatment with donated oocytes on women’s and men’s perception of their relationship has been little studied. Thus the aim of this study was to analyse satisfaction with relationships in couples at the time of acceptance for treatment and 2–5 years after treatment with donated gametes and to compare them with IVF couples treated with their own gametes. Method A prospective follow-up study in which data were collected twice on two groups; cohabitating couples receiving oocyte donation and cohabitating IVF couples using their own gametes. A standardised instrument, the ENRICH inventory, was used to gain information about the couples’ subjective experience of their relationships. Results At acceptance for treatment the couples in the two groups assessed their relationships as being very solid on all dimensions and that the women receiving treatment with oocyte showed a higher satisfaction compared to women treated with own gametes. For couples that did have a child, the group of women who had been through the oocyte donating program reported a better quality of their relationship than women in the control group. There were no significant differences in perceived relationship quality between men in the different groups, whether they had a child or not. Conclusions From a long-term perspective couples using oocyte donation treatment have a balanced and solid view of their relationship and treatment, having children or not after treatment did not affect the nature of the relationships.



Inpatient rehabilitation for hip or knee osteoarthritis: 2 year follow up study  

PubMed Central

Objective: To examine the course of pain, physical function, and other health dimensions after a comprehensive inpatient rehabilitation intervention in patients with osteoarthritis (OA) of the hip or knee. Methods: An observational, prospective cohort study with assessments at baseline (entry into clinic), 1 (discharge from inpatient rehabilitation), 3, 6, 9, 12, and 24 months after baseline. Consecutively referred patients to an inpatient rehabilitation centre fulfilling the inclusion criteria were studied. 3–4 week comprehensive rehabilitation intervention, including strengthening exercise, flexibility training, endurance training, relaxation strategies, and consultations for preventive measures, was carried out. Individual home rehabilitation programmes were taught. Generic health status was measured using the SF-36, condition specific health was measured with the WOMAC questionnaire. Effects were analysed with sensitivity statistics (effect size, ES) and non-parametric tests. Results: Data from 128 patients with complete follow up data were analysed. Both pain and physical function improved moderately (WOMAC pain: ES = 0.56, WOMAC function ES = 0.44) until discharge. Although the effect in pain reduction remained significant by month 24 (WOMAC: ES = 0.26), physical function deteriorated close to baseline values after 12 months. Conclusions: Comprehensive inpatient rehabilitation of patients with OA of the hip or knee may improve pain and physical function in the mid-term, and pain in the long term.

Weigl, M; Angst, F; Stucki, G; Lehmann, S; Aeschlimann, A



Involvement in bullying and suicidal ideation in middle adolescence: a 2-year follow-up study.  


The objective of the study was to ascertain whether involvement in bullying increases the risk for subsequent suicidal ideation. A total of 2,070 Finnish girls and boys aged 15 were surveyed in the ninth grade (age 15) in schools, and followed up 2 years later in the Adolescent Mental Health Cohort Study. Involvement in bullying was elicited at age 15 by two questions focusing on being a bully and being a victim of bullying. Suicidal ideation was elicited by one item of the short Beck Depression Inventory at age 17. Baseline depressive symptoms and externalizing symptoms, age and sex were controlled for. Statistical analyses were carried out using cross-tabulations with Chi-square/Fisher's exact test and logistic regression. Suicidal ideation at age 17 was 3-4 times more prevalent among those who had been involved in bullying at age 15 than among those not involved. Suicidal ideation at age 17 was most prevalent among former victims of bullying. Being a victim of bullying at age 15 continued to predict subsequent suicidal ideation when depressive and externalizing symptoms were controlled for. Being a bully at age 15 also persisted as borderline significantly predictive of suicidal ideation when baseline symptoms were controlled for. Findings indicate adolescent victims and perpetrators of bullying alike are at long-term risk for suicidal ideation. PMID:23053774

Heikkilä, Hanna-Kaisa; Väänänen, Juha; Helminen, Mika; Fröjd, Sari; Marttunen, Mauri; Kaltiala-Heino, Riittakerttu



Course and moderators of emotional eating in anorectic and bulimic patients: A follow-up study.  


Emotion dysregulation has been found to be associated with specific eating attitudes and behavior in Eating Disorder (ED) patients. The present study evaluated whether emotional eating profile of ED patients changes over time and the possible effects of a psychotherapeutic intervention on the emotional eating dimension. One hundred and two ED patients (28 with Anorexia Nervosa restricting type [AN-R], 35 with Anorexia Nervosa binge/purging subtype [AN-B/P] and 39 with Bulimia Nervosa [BN]) were evaluated at baseline, at the end of a Cognitive Behavioral Therapy, at 3 and 6year follow-up. The Structured Clinical Interview for DSM IV Axis I Disorders, the Emotional Eating Scale (EES) and several self-reported questionnaires for eating specific and general psychopathology were applied. A control group of 86 healthy subjects was also studied, in order to compare psychopathological variables at baseline. A significant EES total score reduction was observed among AN-B/P and BN patients, whereas no significant change was found in the AN-R group. Mixed Models analyses showed that a significant effect on EES total score variation was found for cocaine or amphetamine abuse (b=.25; p<.01). Patients who assumed these substances reported no significant EES reduction across time, unlike other patients. The present results suggest that ED patients with a history of cocaine or amphetamine abuse represent a sub-population of patients with lasting dysfunctional mood modulatory mechanisms. PMID:24854803

Fioravanti, Giulia; Castellini, Giovanni; Lo Sauro, Carolina; Ianni, Sirio; Montanelli, Luca; Rotella, Francesco; Faravelli, Carlo; Ricca, Valdo



GLUT1 deficiency syndrome into adulthood: a follow-up study.  


GLUT1 deficiency syndrome (GLUT1DS) is a treatable neurometabolic disorder in which glucose transport into the brain is disturbed. Besides the classic phenotype of intellectual disability, epilepsy, and movement disorders, other phenotypes are increasingly recognized. These include, for example, idiopathic generalized epilepsy and paroxysmal exercise-induced dyskinesia. Since the disorder has only been recognized for two decades and is mostly diagnosed in children, little is known about the disease course. Our purpose was to investigate the disease course of GLUT1DS patients with the classic, complex phenotype from infancy into adulthood. We performed a systematic literature review as well as a cohort study, including GLUT1DS patients aged 18 years and older. The literature search yielded a total of 91 adult GLUT1DS patients, of which 33 patients (one-third) had a complex phenotype. The cohort study included seven GLUT1DS patients with a complex phenotype who were prospectively followed up in our clinic from childhood into adulthood. Our results show that epilepsy is a prominent feature during childhood in classic GLUT1DS patients. During adolescence, however, epilepsy diminishes or even disappears, but new paroxysmal movement disorders, especially paroxysmal exercise-induced dyskinesia, either appear or worsen if already present in childhood. Intellectual disability was not systematically assessed, but cognitive functions appeared to be stabile throughout life. Like children, adolescents may benefit from a ketogenic diet or variants thereof. PMID:24413642

Leen, W G; Taher, M; Verbeek, M M; Kamsteeg, E J; van de Warrenburg, B P; Willemsen, M A



A 15-year follow-up of first unprovoked seizures: a prospective study of 200 children.  


Epilepsy is associated with an extended spectrum of behaviour, psychiatric problems, and learning difficulties. The aim of this study was to establish the natural history of children with first unprovoked seizures. We studied prospectively 200 children under the age of 11 years who attended hospital emergency with a first unprovoked seizure. Demographic variables, personal and family history, neurological examination, EEG, psychiatric, and cognitive and educational profiles were analysed. Patients who developed epilepsy were characterised with respect to: time to relapse, remission rate, duration of epilepsy, neuroimaging, aetiology, epileptic syndrome, and therapeutic regimen. These results were compared to data of patients who had a single seizure over a follow-up period of 15 years. Thirty percent of children who had a first unprovoked seizure developed epilepsy. Partial seizure type was a statistically significant variable for the development of epilepsy. An EEG with epileptic abnormalities proved to be the main risk factor for recurrence. Fifteen years later, the group with epilepsy exhibited a 2.6 greater risk of psychiatric and academic comorbidities, compared to the group without epilepsy. PMID:24691297

Pereira, Cristina; Resende, Cristina; Fineza, Isabel; Robalo, Conceição



Juvenile Hemochromatosis, Genetic Study and Long-term Follow up after Therapy.  


BACKGROUND Hereditary hemochromatosis (HH) is a very rare disease in Iran and reported cases are all negative for HFE mutation. We report a family affected by severe juvenile hemochromatosis (JH) with a detailed molecular study of the family members. METHODS We studied a pedigree with siblings affected by juvenile HH and followed them for 3 years. Microsatellite and gene sequencing analysis was performed for all family members. RESULTS Two siblings (the proband and his sister, aged 26 and 30 years, respectively) were found to have clinical findings of JH. The proband's brother, who presented with hyperpigmentation, died of probable JH at the age of 24 years. Gene sequencing analysis showed that the proband has a homozygote c.265T>C (p.C89R) HJV mutation + a heterozygote c.884T>C (p.V295A) mutation of HFE. The affected proband's sister presented with the same HJV c.265T>C (p.C89R) homozygote mutation. In addition, we found the HJV c.98-6C>G polymorphic variant in both the sister and proband (homozygote). Sequencing of hepcidin (HAMP), TfR2, and FPN revealed no mutation. CONCLUSION We have shown that molecular analysis of the HH related gene is a powerful tool for reliable diagnosis of JH and, in conjunction with magnetic resonance imaging (MRI) and noninvasive liver stiffness measurement by elastography, is adequate tool for management and follow up of HH. PMID:24872867

Malekzadeh, Masoud M; Radmard, Amir Reza; Nouroozi, Alireza; Akbari, Mohammad Reza; Amini, Marzie; Navabakhsh, Behrooz; Caleffi, Angela; Pietrangelo, Antonello; Malekzadeh, Reza



Juvenile Hemochromatosis, Genetic Study and Long-term Follow up after Therapy  

PubMed Central

BACKGROUND Hereditary hemochromatosis (HH) is a very rare disease in Iran and reported cases are all negative for HFE mutation. We report a family affected by severe juvenile hemochromatosis (JH) with a detailed molecular study of the family members. METHODS We studied a pedigree with siblings affected by juvenile HH and followed them for 3 years. Microsatellite and gene sequencing analysis was performed for all family members. RESULTS Two siblings (the proband and his sister, aged 26 and 30 years, respectively) were found to have clinical findings of JH. The proband’s brother, who presented with hyperpigmentation, died of probable JH at the age of 24 years. Gene sequencing analysis showed that the proband has a homozygote c.265T>C (p.C89R) HJV mutation + a heterozygote c.884T>C (p.V295A) mutation of HFE. The affected proband’s sister presented with the same HJV c.265T>C (p.C89R) homozygote mutation. In addition, we found the HJV c.98-6C>G polymorphic variant in both the sister and proband (homozygote). Sequencing of hepcidin (HAMP), TfR2, and FPN revealed no mutation. CONCLUSION We have shown that molecular analysis of the HH related gene is a powerful tool for reliable diagnosis of JH and, in conjunction with magnetic resonance imaging (MRI) and noninvasive liver stiffness measurement by elastography, is adequate tool for management and follow up of HH.

Malekzadeh, Masoud M.; Radmard, Amir Reza; Nouroozi, Alireza; Akbari, Mohammad Reza; Amini, Marzie; Navabakhsh, Behrooz; Caleffi, Angela; Pietrangelo, Antonello; Malekzadeh, Reza



Byssinosis: a follow-up study of workers exposed to fine grade cotton dust  

PubMed Central

A follow-up study was made in a group of cotton workers processing fine grade cotton fibres. Respiratory symptoms and ventilatory capacity were first recorded in 1962 and later in 1971. In 1962, 20 men and 23 women were examined whereas in 1971 only 15 of the men and 13 of the women were still in the mill. In 1962 no case of byssinosis was recorded. The prevalence of chronic cough and chronic bronchitis was higher among men than women. In 1971 the incidence of byssinosis was 20% in men and 23% in women and the prevalence of all other respiratory symptoms had also increased. In men there was a significant mean decrease of the forced expired volume in 0·75 sec (FEV0.75) over the shift both in 1962 (P<0·05) and in 1971 (P<0·01). In women the mean acute decrease of FEV0.75 over the shift in 1962 was not statistically significant (P>0·05), but in 1971 it was (P<0·05). The mean acute reductions of FEV0·75 were considerably higher in 1971 than in 1962. In byssinotics these changes were considerably higher than in non-byssinotics. The chronic effect on ventilatory capacity of exposure to fine cotton dust was not observed in this study.

Valic, Fedor; Zuskin, Eugenija



Radioactive iodine therapy and breast cancer. A follow-up study of hyperthyroid women  

SciTech Connect

A follow-up study of 1762 hyperthyroid women who were treated at the Massachusetts General Hospital Thyroid Unit between 1946 and 1964 was conducted. The average length of follow-up was 17.2 years. A 1978 mailing address or a death certificate was located for 92% of the women, and 88% of 1058 living patients responded to a mail questionnaire. The standardized mortality ratio (SMR) for all causes of death was 1.3 (95% confidence interval (CI) 1.2-1.4). The standardized mortality ratios for all malignant neoplasms and for breast cancer were 0.9 (95% CI 0.7-1.1) and 1.3 (95% CI 0.8-1.9), respectively. More deaths than expected were observed from endocrine and metabolic diseases (SMR = 1.8, 95% CI 1.2-2.7), circulatory system diseases (SMR = 1.4, 95% CI 1.3-1.6), and respiratory system diseases (SMR = 1.9, 95% CI 1.3-2.6). The standardized incidence ratios (SIR) for all malignant neoplasms and for breast cancer were 0.9 (95% CI 0.8-1.1) and 1.2 (95% CI 0.9-1.5), respectively. A nonsignificant excess breast cancer risk was observed 10 years after the onset of thyroid symptoms and was present at the end of 30 years of observation. A statistically significant excess number of pancreatic cancer cases (SIR = 2.0, 95% CI 1.0-3.7) and a nonsignificant excess of brain cancer cases (SIR = 2.3, 95% CI 0.7-5.3) were observed. Eighty per cent of the women were treated with radioactive iodine. When age at treatment and year of treatment were controlled, women who were ever treated with radioactive iodine had a standardized rate ratio for breast cancer of 1.9 (95% CI 0.9-4.1), compared with those who were never treated with radioactive iodine. Women who developed hypothyroidism as a result of their treatment for hyperthyroidism did not have an increased risk of developing breast cancer (SIR = 1.1, 95% CI 0.8-1.6).

Goldman, M.B.; Maloof, F.; Monson, R.R.; Aschengrau, A.; Cooper, D.S.; Ridgway, E.C.



Prognostic significance of transient myocardial ischaemia after first acute myocardial infarction: five year follow up study.  

PubMed Central

OBJECTIVE--To assess the five year prognostic significance of transient myocardial ischaemia on ambulatory monitoring after a first acute myocardial infarction, and to compare the diagnostic and long term prognostic value of ambulatory ST segment monitoring, maximal exercise testing, and echocardiography in patients with documented ischaemic heart disease. DESIGN--Prospective study. SETTING--Cardiology department of a teaching hospital. PATIENTS--123 consecutive men aged under 70 who were able to perform predischarge maximal exercise testing. INTERVENTIONS--Echocardiography two days before discharge (left ventricular ejection fraction), maximal bicycle ergometric testing one day before discharge (ST segment depression, angina, blood pressure, heart rate), and ambulatory ST segment monitoring (transient myocardial ischaemia) started at hospital discharge a mean of 11 (SD 5) days after infarction. MAIN OUTCOME MEASURES--Relation of ambulatory ST segment depression, exercise test variables, and left ventricular ejection fraction to subsequent objective (cardiac death or myocardial infarction) or subjective (need for coronary revascularisation) events. RESULTS--23 of the 123 patients had episodes of transient ST segment depression, of which 98% were silent. Over a mean of 5 (range 4 to 6) years of follow up, patients with ambulatory ischaemia were no more likely to have objective end points than patients without ischaemic episodes. If, however, subjective events were included an association between transient ST segment depression and an adverse long term outcome was found (Kaplan-Meier analysis; P = 0.004). The presence of exercise induced angina identified a similar proportion of patients with a poor prognosis (Kaplan-Meier analysis; P < 0.004). Both exertional angina and ambulatory ST segment depression had high specificity but poor sensitivity. The presence of exercise induced ST segment depression was of no value in predicting combined cardiac events. Indeed, patients without exertional ST segment depression were at increased risk of future objective end points (Kaplan-Meier analysis; P < 0.0045). These findings may be explained in part by a higher prevalence of left ventricular dysfunction in patients without ischaemic changes in the exercise electrocardiogram (P < 0.05). CONCLUSION--There seem to be limited reasons to perform ambulatory ST segment monitoring in survivors of a first myocardial infarction who can perform exercise tests before discharge. Patients at high risk of future myocardial infarction or death from cardiac causes are not identified. Ambulatory monitoring and exertional angina distinguish a small subset of patients who will develop severe angina pectoris demanding coronary revascularisation during follow up. Patients without exercise induced ST segment depression comprise a high risk subgroup in terms of subsequent objective end points. The role of ambulatory ST segment monitoring performed in unselected patients immediately after infarction when risk is maximal remains to be clarified.

Mickley, H.; Nielsen, J. R.; Berning, J.; Junker, A.; M?ller, M.



Clinical implications of alpha-fetoprotein in liver cirrhosis: five-year follow-up study.  


The level of alpha-fetoprotein (AFP) was estimated by radioimmunoassay or passive hemagglutination method in a series of 159 patients with liver cirrhosis, and the incidence of serum hepatitis B antigen, histopathologic features of the liver, incidence of development of hepatocellular carcinoma (HCC) and mortality in AFP-positive cases were studied. Approximately 40 per cent of the patients had an AFP level higher than 20 ng/per ml, and all the elevations of AFP over 100 ng per ml were transient. In contrast, patients who developed HCC during the course of the disease always exhibited an increasing value of AFP. The seropositivity for AFP was significantly related to the presence of serum hepatitis B surface antigen and also to liver cell dysplasia as well as to thickening of the liver cell plates. As compared with a group of AFP-negative cases, the AFP-positive group showed a higher incidence of development of HCC and poorer prognosis over a five-year follow-up period. The data obtained suggested that increased AFP-production in patients with liver cirrhosis might reflect, largely an abnormal or altered liver cell regeneration, probably associated with hepatitis B virus, and that patients with transiently elevated AFP values might be at greater risk for the development of HCC. PMID:6161869

Harada, T; Shigeta, K; Noda, K; Fukumoto, Y; Nishimura, H; Mizuta, M; Takemoto, T



Lipids and All-Cause Mortality among Older Adults: A 12-Year Follow-Up Study  

PubMed Central

This is a 12-year follow-up cohort study with 800 people (60–85 years old). The association between lipid disorders and mortality was analysed by Cox proportional hazard adjusted model. All-cause mortality was considered the dependent variable, and lipid disorders as independent variables: total cholesterol (TC) >200 and <170?mg/dl, HDL-c <35 and 40, LDL-c >100 and 130, and triglycerides (TG) >50. An initial analysis of all subjects was performed and a second was carried out after having excluded individuals with a body mass index (BMI) <20?kg/m2 or mortality in ?2 years. The mortality showed a positive association with low TC and a negative association with high TC and high LDL-c. After the exclusion of underweight and premature mortality, there was a positive association only with TC <170?mg/dl (HR = 1.36, CI95%: 1.02–1.82). The data did not show a higher risk with high levels of TC, LDL-c, and TG. However, they showed higher mortality among older adults with low TC.

Cabrera, Marcos Aparecido Sarria; de Andrade, Selma Maffei; Dip, Renata Maciulis



[Follow-up study of bone grafts to the alveolar clefts].  


Clinical follow-up study after the grafting with fresh autogenous iliac bone to the alveolar clefts in cleft lip and palate patients was carried out up to 2 years post operation. Twenty two patients were examined, to whom grafts of iliac cortical or iliac marrow bone was carried out by the First or the Second Department of Oral Surgery, Kagoshima University Dental School from July, 1985 to April, 1988. Their cleft types were classified as 18 unilateral and 4 bilateral cleft lips and palates. The ages at bone grafting were ranged from 8 years 9 months to 17 years 6 months, and the average of which was 12 years 3 months. Nine of these patients were grafted with the cortical bone, and the other 13 were grafted with the marrow bone. The perforations at alveolar clefts were covered with the tongue flap in 10 clefts of 10 patients, while they were covered with the local mucous flap in 15 clefts of 12 patients. Among these patients, dental casts, X-ray radiograms and oral pictures of 15 patients were surveyed postoperatively. Results were as follows: 1) Contours of the alveolar clefts were well corrected in 9 patients, especially in those cases of pre-operatively expanded unilateral clefts, grafted with the marrow bone and covered with the local mucous flaps. 2) The viable rate of grafted bone was 100.0% for the marrow bone, while it was 62.5% for the cortical bone.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:2701290

Yamauchi, K; Maruta, Y; Uemura, K; Ito, G



Treatment of tuberculum sellae meningiomas:a long-term follow-up study.  


Surgical techniques and their results for tuberculum sellae meningiomas were studied. Thirty-three cases, the first of which was operated in 1980, were analysed. There were 4 men and 29 women with an average age of 46.7 years. Eight cases underwent reoperations. The mean follow-up was 10.7 years. Approaches were pterional for 15 patients, FOZ/FO for 10, bilateral subfrontal for 6, and others for 2. Simpson's grade (I, II, III, IV) were 12, 9, 0, and 12 cases respectively. Recurrence rate was 0% for grade I and 58.3% for grade IV. The FOZ/FO approach resulted in a lower Simpson's grade (P=0.05), but other factors were not related to Simpson's grade (P=0.05). The postoperative visual outcome did not depend on total (grade I and II) or subtotal (grade III and IV) removal (P=0.01). We conclude that radical removal of the tumours may result in lower recurrence rate without increasing surgical complications. Furthermore, skull base approaches can improve the rate of radical removal of tuberculum sellae meningiomas. PMID:11386822

Ohta, K; Yasuo, K; Morikawa, M; Nagashima, T; Tamaki, N



Afterglow Population Studies from Swift Follow-Up Observations of Fermi LAT GRBs  

NASA Technical Reports Server (NTRS)

The small population of Fermi LAT detected GRBs discovered over the last year has been providing interesting and unexpected clues into GRB prompt and afterglow emission mechanisms. Over the last 5 years, it has been Swift that has provided the robust data set of UV/optical and X-ray afterglow observations that opened many windows into other components of GRB emission structure. We explore the new ability to utilize both of these observatories to study the same GRBs over 10 orders of magnitude in energy, although not always concurrently. Almost all LAT GRBs that have been followed-up by Swift within 1-day have been clearly detected and carefully observed. We will present the context of the lower-energy afterglows of this special subset of GRBs that has > 100 MeV emission compared to the hundreds in the Swift database that may or may not have been observed by LAT, and theorize upon the relationship between these properties and the origin of the high energy gamma-ray emission.

Racusin, Judith L.; Oates, S. R.; McEnery, J.; Vasileiou, V.; Troja, E.; Gehrels, N.



Do neuroleptic drugs hasten cognitive decline in dementia? Prospective study with necropsy follow up.  

PubMed Central

OBJECTIVE: To investigate the contribution of neuroleptic drugs to cognitive decline in dementia. DESIGN: Two year prospective, longitudinal study consisting of interviews every four months, with necropsy follow up. SETTING: Community settings in Oxfordshire. SUBJECTS: 71 subjects with dementia, initially living at home with informant. MAIN OUTCOME MEASURES: Cognitive function (score from expanded minimental state examination); behavioural problems (physical aggression, hallucinations, persecutory ideas, and disturbance of diurnal rhythm); and postmortem neuropathological assessment (cortical Lewy body pathology). RESULTS: The mean (SE) decline in cognitive score in the 16 patients who took neuroleptics was twice that in the patients who did not (20.7 (2.9) v 9.3 (1.3), P = 0.002). An increased rate of decline was also associated with aggression, disturbed diurnal rhythm, and persecutory ideas. However, only use of neuroleptics and severity of persecutory ideas were independently associated with more rapid cognitive decline when all other variables were adjusted for. The start of neuroleptic treatment coincided with more rapid cognitive decline: median rate of decline was 5 (interquartile range 8.5) points per year before treatment and 11 (12) points per year after treatment (P = 0.02). Cortical Lewy body pathology did not account for association between neuroleptic use and more rapid decline. CONCLUSIONS: Neuroleptic drugs that are sometimes used to treat behavioural complications of dementia may worsen already poor cognitive function. Randomised controlled trials are needed to confirm a causal relation.

McShane, R.; Keene, J.; Gedling, K.; Fairburn, C.; Jacoby, R.; Hope, T.



Counselling for Patients and Family Members: A Follow-Up Study in the Emergency Department  

PubMed Central

Although the research indicates that patients and family members are not fully satisfied with the counselling they receive, little is known about the quality of counselling in more detail. The purpose of the study was to describe patients' and their family members' experiences about counselling in emergency department, and follow how these experiences possibly change after the educational intervention for the whole nursing staff of the ED ward. The pre-test-post-test follow-up design was implemented including online continuing education for ED staff. The data were collected via questionnaires from patients and their family members in two phases and analyzed statistically. After online education of staff, experiences of patients and family members concerning counselling were better than before the education. Especially, family members' satisfaction had increased. However, our results also indicated that patients and family members desire more information for example, regarding medications. Care practices had developed towards family-centeredness, which patients and family members appreciate. Online education proved also in some degree its usefulness in educating ED staff, by offering the same education to a staff which works in shifts. Furthermore, family presence and participation practices should be developed by offering possibilities for families to stay with each other on ED ward.

Paavilainen, Eija; Salminen-Tuomaala, Mari; Leikkola, Paivi



Pattern and motion-related visual-evoked potentials in neuroborreliosis: follow-up study.  


Visual-evoked potentials (VEPs) were used for objective testing of visual functions during treatment courses of Lyme neuroborreliosis (LNB) in adult patients in the Czech Republic. In 30 LNB patients with originally delayed VEP latencies, pattern-reversal (R-VEP) and motion onset (M-VEP) VEPs were repeatedly examined within 1 to 8 years. Six patients had Lyme optic neuritis (ON), five of them displayed prolonged latencies in both R-VEPs and M-VEPs, and one had only abnormal R-VEPs. The VEP recovery to normal latency values was in three of them. In the group of 24 LNB patients without ON, 14 patients displayed prolonged latencies only to motion stimuli, and 10 patients had abnormal latencies in both R-VEPs and M-VEPs. During the follow-up period, 7 patients displayed shortening to normal latencies. In 5 patients, VEPs latencies improved only partially, and in the remaining 12 patients, VEPs did not improve at all. This study provides objective evidence that in LNB, most of the patients without clinically manifesting ON display optic pathway involvement-predominantly magnocellular system/dorsal stream function changes. In patients with ON, however, mainly the parvocellular system is affected. About half of the patients without ON improved with a relatively long-time course of latency shortening. PMID:22469684

Szanyi, J; Kubová, Z; Kremlá?ek, J; Langrová, J; Vít, F; Kuba, M; Szanyi, J; Plíšek, S



Risk factors for criminal recidivism - a prospective follow-up study in prisoners with substance abuse  

PubMed Central

Background Substance use in general has been shown to predict criminal recidivism. The present study aimed to examine potential predictors of criminal recidivism, including substance-specific substance use patterns, in prisoners with substance use. Methods A cohort of prisoners with substance use problems (N?=?4,152) were assessed with the Addiction Severity Index (ASI) in the Swedish criminal justice system. Clients were followed for an average of 2.7?years. Criminal recidivism was defined as any return to the criminal justice system. Results During follow-up, 69 percent (n?=?2,862) returned to the criminal justice system. Recidivism was associated with amphetamine and heroin use, with an additive risk for injectors, and with polysubstance use. Also, recidivism was negatively associated with alcohol, other opioids than heroin/methadone and with hallucinogenic drugs, and positively associated with previous psychiatric in-patient treatment, violent behaviour, and with a shorter index sentence. Associations remained when controlling for type of crime. Conclusions Even when controlling for type and severity of crime, and for psychiatric problems, risk of criminal relapse was increased by substance use variables, including amphetamine, heroin and polysubstance use, and an additional risk was shown for injection drug users. These findings have implications for the need for substance abuse treatment after release from prison.



Fifteen year follow-up study of VC and FEV1 in dust-exposed workers.  


A baseline survey of 3457 male workers exposed to various forms of dust from 11 medical facilities throughout Japan was carried out in 1978 or 1979. We completed the present follow-up study 15 years later on 693 of the men. Vital capacity (VC) and forced expiratory volume in one second (FEV1) were analyzed as indices of lung function. We examined factors that affected both baseline and interval changes in VC and FEV1 by stepwise multiple regression analysis. In the cross-sectional data analysis of baseline, height, profusion rate (PR) and age were selected as predictor variables for VC and FEV1, additionally duration of working for FEV1. It indicated that baseline VC decreased by 84.0 ml with each increase in PR classification. Similarly, baseline FEV1 decreased by 146.6 ml with increasing PR. Baseline VC and FEV1 were both positively influenced by subject height. In the longitudinal analysis, baseline PR, age and smoking habits were selected for predictor variables for decline of VC and FEV1. It indicated a negative influence of baseline PR classification on VC and FEV1 changes (-5.0 and -7.5 ml/y, respectively). Smoking decreased VC and FEV1 by 6.1 and 5.8 ml/y, respectively. PMID:11341555

Taguchi, M; Aizawa, Y; Niitsuya, M; Sugiura, Y; Tonori, H; Tonori, Y



Follow-up study after more than one year including 100 patients treated for superficial mycoses.  


A total of 100 patients with dermatomycoses were treated with econazole nitrate 1% or with the same compound combined with triamcinolone acetonide 0.1%. The patients were supposed to undergo clinical and mycological follow-up examinations at an average of 15 months after cure had been obtained. Of the 100 patients, 83 were followed up: 78 (95%) reported neither relapses nor reinfections; 4 (5%) presented with clinical symptoms and positive mycological examination and in 1 patient the mycological examination was positive but no clinical symptoms were present. Generally speaking, the results can be considered excellent. PMID:7351270

Grigoriu, D; Pallarés, J L



Long term functioning in early onset psychosis: Two years prospective follow-up study  

PubMed Central

Background There were few studies on the outcome of schizophrenia in developing countries. Whether the outcome is similar to or different from developed world is still a point for research. The main aim of the current study was to know if patients with early onset non affective psychosis can behave and function properly after few years from start of the illness or not. Other aims included investigation of possible predictors and associated factors with remission and outcome. Method The study prospectively investigated a group of 56 patients with onset of psychosis during childhood or adolescence. Diagnosis made according to DSM-IV criteria and included; schizophrenia, psychotic disorder not otherwise specified and acute psychosis. Severity of psychosis was measured by PANSS. Measures of the outcome included; remission criteria of Andreasen et al 2005, the children's global assessment scale and educational level. Results Analysis of data was done for only 37 patients. Thirty patients diagnosed as schizophrenia and 7 with Psychotic disorder not otherwise specified. Mean duration of follow up was 38.4 +/- 16.9 months. At the end of the study, 6 patients (16.2%) had one episode, 23(62.1%) had multiple episodes and 8 (21.6%) continuous course. Nineteen patients (51.4%) achieved full remission, and only 11(29.7%) achieved their average educational level for their age. Twenty seven percent of the sample had good outcome and 24.3% had poor outcome. Factors associated with non remission and poor outcome included gradual onset, low IQ, poor premorbid adjustment, negative symptoms at onset of the illness and poor adherence to drugs. Moreover, there was tendency of negative symptoms at illness start to predict poor outcome. Conclusion Some patients with early onset non affective psychosis can behave and function properly after few years from the start of the illness. Although remission is a difficult target in childhood psychosis, it is still achievable.



Mechanical Engineering Curricula: A Follow-up Study for the Future Effects of ABET EC2000  

NSDL National Science Digital Library

The Accreditation Board for Engineering and Technology (ABET) is recognized by the U.S. Department of Education as the sole agency responsible for accreditation of educational programs leading to degrees in engineering, engineering technology, and related engineering areas. In the late 1990s, engineering programs began transitioning to a new Engineering Criteria 2000 (EC2000). By 2001, all engineering programs were required to be accredited under the new criteria. The philosophy of Engineering Criteria 2000 is to allow institutions and programs to define their mission and objectives to meet the needs of their constituents and enable program differentiation. Emphasis is placed on continuous improvement of programs based on the input of constituents and a process that links outcomes and assessment to program objectives. This current paper is a follow-up study to a preliminary study conducted by the author in 2000 that looked at the initial effects of ABET EC2000. The earlier study examined selected mechanical engineering programs to discern the impact of EC2000 on curriculum development during the initial implementation phase of the new criteria. Data on the layout and composition of mechanical engineering curricula for nine schools in the United States with Ph.D. programs and nine schools without Ph.D. programs was presented and is updated in this current work. Current results are also compared to a study by Robert E. Mates from the State University of New York at Buffalo entitled a Survey of Undergraduate ME Programs, conducted in 1987. The conclusions identify changes that have occurred in mechanical engineering curricula as the EC2000 assessment process has matured.

Whiteman, Wayne




Microsoft Academic Search

A randomized ten-year follow-up study involving 91 Chagas patients and 41 uninfected controls was undertaken to determine the effectiveness of nitroderivative therapy. Anti- Trypanosoma cruzi antibodies were con- sistently lower one year after treatment than 10 years thereafter ( P 0.001). The blood of all treated and 93.7% of untreated Chagas patients yielded polymerase chain reaction (PCR) product from probes




Serum Adiponectin and Type 2 Diabetes: A 6-Year Follow-Up Cohort Study  

PubMed Central

Background Studies on factors which may predict the risk of diabetes are scarce. This prospective cohort study was conducted to determine the association between adiponectin and type 2 diabetes among Korean men and women. Methods A total of 42,845 participants who visited one of seven health examination centers located in Seoul and Gyeonggi province, Republic of Korea between 2004 and 2008 were included in this study. The incidence rates of diabetes were determined through December 2011. To evaluate the effects of adiponectin on type 2 diabetes, the Cox proportional hazard model was used. Results Of the 40,005 participants, 959 developed type 2 diabetes during a 6-year follow-up. After the adjustment for age, body mass index (BMI), and waist circumference, the risks for type 2 diabetes in participants with normoglycemia had a 1.70-fold (95% confidence interval [CI], 1.21 to 2.38) increase in men and a 1.83-fold (95% CI, 1.17 to 2.86) increase in women with the lowest tertile of adiponectin when compared to the highest tertile of adiponectin. For participants with impaired fasting glucose (IFG), the risk for type 2 diabetes had a 1.46-fold (95% CI, 1.17 to 1.83) increase in men and a 2.52-fold (95% CI, 1.57 to 4.06) increase in women with the lowest tertile of adiponectin. Except for female participants with normoglycemia, all the risks remained significant after the adjustment for fasting glucose and other confounding variables. Surprisingly, BMI and waist circumference were not predictors of type 2 diabetes in men or women with IFG after adjustment for fasting glucose and other confounders. Conclusion A strong association between adiponectin and diabetes was observed. The use of adiponectin as a predictor of type 2 diabetes is considered to be useful.

Ahn, Chul Woo; Park, Jong Suk; Park, Chang Gyu; Kim, Hyon-Suk; Lee, Sang-Hak; Park, Sungha; Lee, Myoungsook; Lee, Chang Beom; Park, Hye Soon; Kimm, Heejin; Choi, Sung Hee; Sung, Jidong; Oh, Seungjoon; Joung, Hyojee; Kim, Sung Rae; Youn, Ho-Joong; Kim, Sun Mi; Lee, Hong Soo; Mok, Yejin; Choi, Eunmi; Yun, Young Duk; Baek, Soo-Jin; Jo, Jaeseong; Huh, Kap Bum



Outcome of combined unicompartmental knee replacement and combined or sequential anterior cruciate ligament reconstruction: a study of 52 cases with mean follow-up of five years.  


The Oxford unicompartmental knee replacement (UKR) is an established treatment option in the management of symptomatic end-stage medial compartmental osteoarthritis (MCOA), which works well in the young and active patient. However, previous studies have shown that it is reliable only in the presence of a functionally intact anterior cruciate ligament (ACL). This review reports the outcomes, at a mean of five years and a maximum of ten years, of 52 consecutive patients with a mean age of 51 years (36 to 57) who underwent staged or simultaneous ACL reconstruction and Oxford UKR. At the last follow-up (with one patient lost to follow-up), the mean Oxford knee score was 41 (sd 6.3; 17 to 48). Two patients required conversion to TKR: one for progression of lateral compartment osteoarthritis and one for infection. Implant survival at five years was 93% (95% CI 83 to 100). All but one patient reported being satisfied with the procedure. The outcome was not significantly influenced by age, gender, femoral or tibial tunnel placement, or whether the procedure was undertaken at one- or two-stages. In summary, ACL reconstruction and Oxford UKR gives good results in patients with end-stage MCOA secondary to ACL deficiency. PMID:22933493

Weston-Simons, J S; Pandit, H; Jenkins, C; Jackson, W F M; Price, A J; Gill, H S; Dodd, C A F; Murray, D W



Follow-Up Study of Former Students of the Data Processing Program. Volume XVI, No. 3.  

ERIC Educational Resources Information Center

In spring 1987, a follow-up survey was conducted of former William Rainey Harper College (WRHC) students who had taken five or more data processing courses at the college between 1980 and 1986. The survey focused on the students' employment status and educational intent while attending WRHC, their present employment situation, and their evaluation…

Rilki, Ernest; Lucas, John A.


Enhanced physical therapy for arm function after stroke: a one year follow up study  

Microsoft Academic Search

Ninety seven patients with stroke who had participated in a randomised trial of conventional physical therapy nu an enhanced therapy for arm function were followed up at one year. Despite the emphasis of the enhanced therapy approach on continued use of the arm in everyday life, the advantage seen for some patients with enhanced therapy at six months after stroke

A Sunderland; D Fletcher; L Bradley; D Tinson; R L Hewer; D T Wade



Tissue Polypeptide Antigen (TPA) in Urinary Bladder Cancer Cytology: A Follow-Up Study  

Microsoft Academic Search

Tissue polypeptide antigen (TPA) has been detected by immunocytochemical assay on urine cytological samples from 28 asymptomatic patients, who previously had a histological diagnosis of papillary transitional cell carcinoma (PTCT) of the urinary bladder (UB), in order to evaluate its role in follow-up controls. TPA staining intensity (SI) in urothelial cells was evaluated to improve the diagnostic accuracy of cytology.

S. Senatore; L. Zizzi; C. Blasi; G. Alfieri; Saccani Jotti; M. Gabrielli; S. Luccarelli



Hawaii Community College Vocational-Technical Graduate Follow-Up Studies, 1968-1971.  

ERIC Educational Resources Information Center

This follow-up survey of Hawaii Community College vocational-technical graduates from 1968-1971 was undertaken to (1) indicate general trends in their labor force status, and (2) determine how these trends might be used to evaluate present programs. The first part of the report presents cumulative trends for 1968-1971, and the second part focuses…

Hawaii Univ., Honolulu. Community Coll. System.


A Long-Term Follow-Up Study in Essential Cryoglobulinemia  

Microsoft Academic Search

In a case series of 56 patients with essential cryoglobulinemia, 35 were followed-up for 4–13 years (mean 7 years). A membranous proliferative glomerulonephritis, which in about half the cases showed a progression to renal insufficiency, was the commonest complication, observed in more than one third of the patients. In 2 patients hepatic cirrhosis became manifest after a completely asymptomatic period

F. Invernizzi; P. Pioltelli; R. Cattaneo; V. Gavazzeni; P. Borzini; G. Mont; C. Zanussi



A follow up study of vibration induced white finger in compensation claimants  

Microsoft Academic Search

Aims: To follow up vibration induced white finger (VWF) in a selected group of 73 vibration exposed workers who claimed unsuccessfully for VWF compensation at a first examination.Methods: The VWF claimants were sent to our unit by the National Insurance Institute. The basic compensatory criteria included a positive history of VWF and abnormal cold response of the digital arteries. Following

M Bovenzi; A Della Vedova; C Negro



Religious Attitudes of Women College Students: A Follow-Up Study.  

ERIC Educational Resources Information Center

Reports a follow-up of the religious attitudes of freshwomen from 1979-1980 reported by McAllister (1981). Results suggest that students of the 1980s are more religious than those of previous years, and that there is a decrease in religious behavior during the college years although not in religious attitudes or theological beliefs. (Author/BL)

McAllister, Edward W. C.



A Follow-Up Study of Infantile Autism in Hong Kong.  

ERIC Educational Resources Information Center

The demographic, family, medical, and psychiatric characteristics of 87 autistic children, age 3-16, in Hong Kong are described. Follow up of 66 children found the sample to be similar to samples in other countries in sex ratio, intelligence, language ability, behavioral characteristics, and outcome. The Hong Kong sample was dissimilar in other…

Chung, S. Y.; And Others



A 2-Year Prospective Follow-Up Study of the Course of Obsessive-Compulsive Disorder  

PubMed Central

Background Surprisingly little is known about the long-term course of obsessive-compulsive disorder (OCD). This prospective study presents 2-year course findings, as well as predictors of course, from the Brown Longitudinal Obsessive Compulsive Study, the first comprehensive prospective investigation of the observational course of OCD in a large clinical sample. Method The sample included 214 treatment-seeking adults with DSM-IV OCD at intake who identified OCD as the most problematic disorder over their lifetime. Subjects were enrolled from 2001–2004. At annual interviews, data on weekly OCD symptom status were obtained using the Longitudinal Interval Follow-Up Evaluation. Probabilities of full remission and partial remission over the first 2 years of collected data and potential predictors of remission were examined. Results The probability of full remission from OCD was 0.06, and the probability of partial remission was 0.24. Of the 48 subjects whose OCD symptoms partially or fully remitted, only 1 relapsed within the first 2 years. Earlier age at onset of OCD, greater severity of symptoms at intake, older age at intake, and being male were associated with a decreased likelihood of remission. Insight, diagnostic comorbidity, and treatment were not found to be associated with the likelihood of achieving full or partial remission. Conclusions Though one-quarter of the sample had periods of subclinical OCD symptoms during the prospective period, full remission was rare, consistent with the view of OCD as a chronic and persistent illness. Age at onset, OCD symptom severity, current age, and sex emerged as potent predictors of course.

Eisen, Jane L.; Pinto, Anthony; Mancebo, Maria C.; Dyck, Ingrid R.; Orlando, Maria E.; Rasmussen, Steven A.



Sleep, physical activity and BMI in six to ten-year-old children measured by accelerometry: a cross-sectional study  

PubMed Central

Background The aim of this study is to describe the relationship between objective measures of sleep, physical activity and BMI in Swedish pre-adolescents. The day-to-day association between physical activity and sleep quality as well as week-day and weekend pattern of sleep is also described. Method We conducted a cross sectional study consisted of a cohort of 1.231 children aged six to ten years within the Stockholm county area. Sleep and physical activity were measured by accelerometry during seven consecutive days. Outcome measures are total sleep time, sleep efficiency, sleep start and sleep end; physical activity intensity divided into: sedentary (<1.5 METS), light (1.5 to 3 METS) and moderate-to-vigorous (> 3 METS); and Body Mass Index standard deviations score, BMIsds. Results Total sleep time decreased with increasing age, and was shorter in boys than girls on both weekdays and weekends. Late bedtime but consistent wake-up time during weekends made total sleep time shorter on weekends than on weekdays. Day-to-day within-subject analysis revealed that moderate-to-vigorous intense physical activity promoted an increased sleep efficiency the following night (CI?ten year old children. This study underscores the importance of consistent bedtimes throughout the week for promoting sleep duration in preadolescents. Furthermore, this study suggests that a large proportion of intensive physical activity during the day might promote good sleep quality.



Three cases of CLIPPERS: a serial clinical, laboratory and MRI follow-up study.  


The aim of the study was to further determine the pathophysiology, clinical course, MRI-features and response to therapy of chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS), which has recently been proposed as a rare chronic inflammatory central nervous system disorder responsive to immunosuppressive therapy. Three patients with this rare entity underwent serial clinical and bimonthly MRI follow-up over a period of up to 16 months. Extensive laboratory work-up and brain biopsy were performed. Intravenous methylprednisolone or oral dexamethasone was administered as treatment, additionally cyclophosphamide in one patient. Clinically, diplopia, nystagmus, ataxia and facial paresthesia were the cardinal symptoms. Magnetic resonance imaging (MRI) disclosed patchy spot-like gadolinium enhancement in a "salt-and-pepper like appearance" in the pons, midbrain and cerebellum, in two cases with thalamic and in the other with spinal involvement. Brain biopsies demonstrated a predominantly angiocentric but also diffuse infiltration pattern by small mature lymphocytes. Treatment with steroids led to rapid clinical improvement and marked resolution of MRI lesions. As discontinuation of steroids led to clinical relapse, one patient was treated with a further course of steroids and the other with steroids and cyclophosphamide as immunosuppressive therapy. This led to stable remission with only mild clinical residue and normalization of MRI. Extensive laboratory and radiological work-up could not identify any other cause of the disease. Of note, in two cases a marked elevation of IgE in serum was found initially and throughout the course. CLIPPERS seems to be a distinct inflammatory central nervous system disorder. It shows characteristic MRI core features. Extrapontine involvement seems to be frequent. Histologically it is characterised by predominantly angiocentric infiltration by small mature lymphocytes. A pathogenetic relationship between the elevated IgE levels and the perivascular infiltrates can be presumed. It is responsive to immunosuppressive therapy and can require prolonged or maintenance treatment. PMID:21556878

Kastrup, O; van de Nes, J; Gasser, T; Keyvani, K



One-year follow-up of Chinese people with spinal cord injury: A preliminary study  

PubMed Central

Background A tertiary spinal cord injury (SCI) center was established in the northern region of Hong Kong, China and a multidisciplinary SCI rehabilitation program was developed to reintegrate patients into the community. Objective To investigate functional outcomes for Chinese people with SCI across a 1-year period. Design Longitudinal prospective design. Methods Thirty community-dwelling participants with traumatic SCI were recruited. Functional status was measured using functional independence measure (FIM) on admission, upon discharge, 1-month, 3-month, 6-month, and 1-year post-discharge. Information on use of assistive devices and life role were also obtained. Results Twenty-three (76.67%) participants were men. Seventeen participants (10 with tetraplegia and 7 with paraplegia) were classified ASIA A, B, or C; 13 (7 with tetraplegia and 6 with paraplegia) were classified as ASIA D. Significant differences in FIM motor scores were only found between the tetraplegia group and three other diagnostic groups using Bonferroni post-hoc tests of repeated measure ANOVA (analysis of variance) (P < 0.05). Longitudinally, contrast tests of repeated measure ANOVA showed significant differences during the hospitalization period for all diagnostic groups. People in the ASIA D group showed significant functional improvement even after 1-year post-discharge (P < 0.05). At 1-year post-discharge, only two participants were engaged in either remunerative employment or academic pursuit. Conclusion Despite functional status improvement, few people with traumatic SCI were re-engaged in productive life role 1 year after discharge. Studies with longer follow-up would be beneficial.

Chan, Sam Chi Chung; Chan, Alice Po Shan



Employment grade differences in cause specific mortality. A 25 year follow up of civil servants from the first Whitehall study  

Microsoft Academic Search

STUDY OBJECTIVETo test the hypothesis that the association between socioeconomic status and mortality rates cuts across the major causes of death for middle aged and elderly men.DESIGN25 year follow up of mortality in relation to employment grade.SETTINGThe first Whitehall study.PARTICIPANTS18 001 male civil servants aged 40–69 years who attended the initial screening between 1967 and 1970 and were followed up

Caroline T M van Rossum; Martin J Shipley; Hendrike van de Mheen; Diederick E Grobbee; Michael G Marmot



A follow-up study of cognitive bias in generalized anxiety disorder  

Microsoft Academic Search

Patients with generalized anxiety disorder (GAD) without concurrent depression (n = 11) and normal controls (n = 17) were tested twice, about 2 months apart, on a modified Stroop colour-naming task, which presented anxiety-related, depression-related and neutral words in masked and unmasked exposure conditions. GAD patients received cognitive behaviour therapy in the test-retest interval, and were also retested at follow-up,

Karin Mogg; Brendan P. Bradley; Neil Millar; Jim White



Dynamic Temporal Change of Cerebral Microbleeds: Long-Term Follow-Up MRI Study  

PubMed Central

Background Cerebral microbleeds (MBs) are understood as an important radiologic marker of intracerebral hemorrhage. We sought to investigate the temporal changes of MBs and clinical factors associated with the changes using long-term follow-up MRI. Methods/Principal Findings From October 2002 to July 2006, we prospectively enrolled patients with stroke or transient ischemic attack, and followed-up their brain MRIs with an interval >12 mo. We compared demographic factors, vascular risk factors, laboratory findings, and radiologic factors according to the presence or changes of MBs. A total of 224 patients successfully completed the follow-up examinations (mean, 27 months). Newly developed MBs were noted in 10 patients (6.8%) among those without MBs at baseline (n?=?148), and in those with MBs at baseline (n?=?76), the MB count had decreased in 11 patients (14.5%), and increased in 41 patients (53.9%). The estimated annual rate of change of MB numbers was 0.80 lesions per year in all patients, a value which became greater in those patients who exhibited MBs at baseline (MBs?5, 5.43 lesions per year). Strokes due to small vessel occlusion and intracerebral hemorrhage, as well as white matter lesions were independently associated with an increased MB count, whereas the highest quartile of low-density lipoprotein (LDL) cholesterol was associated with a decreased MB count. Conclusion During the follow-up period, most of MBs showed dynamic temporal change. Symptomatic or asymptomatic small vessel diseases appear to act as risk factors while in contrast, a high level of LDL cholesterol may act as a protective factor against MB increase.

Kim, Beom Joon; Park, Hee-Kwon; Kim, Chi-Kyung; Jung, Keun-Hwa; Roh, Jae-Kyu



Confabulation and Delusional Misidentification: A Four Year Follow-Up Study  

Microsoft Academic Search

We describe a patient, AZ, who showed, in addition to an amnesic syndrome which eventually improved, longstanding confabulation and delusional misidentification following bilateral frontal and right temporal post-traumatic lesions. Confabulation appeared in personal recollections and on long-term verbal memory testing. Misidentification concerned mainly his wife and house. During the four year follow-up AZ's confabulation progressively shrinked so as to become

Flavia Mattioli; Antonio Miozzo; Luigi A. Vignolo



Follow-up Study of Operating Room Technician Graduates. Vol. VIII, No. 9.  

ERIC Educational Resources Information Center

A follow-up survey on the employment of the 55 recent (1973-1976) graduates of the Operating Room Technician (ORT) program at William Rainey Harper College revealed that 51.2% of the 41 respondents had some college work prior to Harper enrollment; 63.5% were currently employed full-time, 14.5% part-time, 17% were voluntarily unemployed, and 5%…

Phillips, Shirley C.; Lucas, John A.


Follow-up of psychogenic, non-epileptic seizures: a pilot study — experience in a Dutch special centre for epilepsy  

Microsoft Academic Search

A follow-up study was performed in 33 patients with proven (ictal EEG-CCTV) psychogenic, non-epilptic seizures (PNES). These patients received a questionnaire to evaluate seizures, treatment and rehabilitation. The response group consisted of 21 females (80% response) and seven males (100% response). Follow-up after diagnosis varied from 23–67 months. Seven patients (25%) reported that seizures had ceased and of the patients

J. M. Mommers; W. O. Renier; H. Meinardi



Change in quality of life of medically hospitalized patients – A one-year follow-up study  

Microsoft Academic Search

Objectives: To examine changes in quality of life (QOL) among elderly medically hospitalized patients one year after hospitalization, and to explore factors associated with the changes.Methods: A one-year follow-up study included 363 (175 men) medical inpatients with age range 65–98 (mean 80.2, SD 7.5) years. Information was collected at baseline and follow-up using the WHOQOL-BREF questionnaire assessing the physical, psychological,

Anne-Sofie Helvik; Knut Engedal; Geir Selbæk



Sociodemographic and Psychopathological Risk Factors for Repetition of Attempted Suicide: A 5Year Follow-Up Study  

Microsoft Academic Search

The present study examines the association between repetition of suicide attempts and sociodemographic and psychopathological characteristics of patients during a 5-year follow-up period. Participants were 874 suicide attempters referred to the University Hospital of Ghent, among whom 361 (41.3%) patients were available for follow-up analysis. Within 5 years, 29.2% of those admitted for an index suicide attempt repeated non-fatal suicidal

Gerrit Scoliers; Gwendolyn Portzky; Kees van Heeringen; Kurt Audenaert



A Long-Term Follow-Up Study on Endoscopic Management of Children and Adolescents With Chronic Pancreatitis  

Microsoft Academic Search

OBJECTIVES:Data on therapeutic endoscopic retrograde cholangiopancreatography (ERCP) for chronic pancreatitis (CP) in children and adolescents, especially with long-term follow-up of consequences, are rarely reported. The aim of this study was to determine the long-term follow-up results of therapeutic ERCP for CP in children and adolescents.METHODS:All patients with CP who received therapeutic ERCP at Changhai Hospital from January 1997 to May

Zhao-Shen Li; Wei Wang; Zhuan Liao; Duo-Wu Zou; Zhen-Dong Jin; Jie Chen; Ren-Pei Wu; Feng Liu; Luo-Wei Wang; Xin-Gang Shi; Zhao Yang; Li Wang



GuLF Study: The Gulf Long-Term Follow-Up Study  


... of Environment, Lifestyle & Fibroids (SELF) Studies Study of Environment, Lifestyle & Fibroids (SELF) Study of Estrogen Activity and Development (SEAD) Soy Study Studies Study of Estrogen Activity ...


Mortality attributable to cigarette smoking in Taiwan: a 12-year follow-up study  

PubMed Central

BACKGROUND—Assessment of the impact of cigarette smoking on mortality helps to indicate the importance of tobacco control in a given country.?OBJECTIVES—To examine the relative risk of dying from various diseases for cigarette smoking and to estimate annual mortality attributable to cigarette smoking in Taiwan.?DESIGN—Prospective cohort study.?SUBJECTS AND SETTING—A cohort of 14 397 male and female residents aged 40 years or older recruited from 12 townships and precincts in Taiwan from 1982 to 1986. Information on cigarette smoking was collected from each subject at local health centres through a standardised personal interview based on a structured questionnaire. They were followed up regularly to determine their vital status until 1994.?MAIN OUTCOME MEASURES—Cox's proportional hazards regression models were used to derive relative risks of cause-specific mortality for current cigarette smokers compared with never-smokers, and to examine dose-response relationships between mortality from various causes and several measures of cigarette smoking (daily consumption, duration, age of initiation, and cumulative smoking in pack-years).?RESULTS—A total of 2552 persons died during the study period. Among men, cigarette smoking was significantly associated with an increased risk of dying from all causes combined (relative risk (RR) = 1.3); cancer of all sites combined (RR = 1.5); cancers of the stomach (RR = 1.9), liver (RR = 2.2), and lung (RR = 3.7); ischaemic heart disease (RR = 1.8); other heart diseases (RR = 1.4); and chronic obstructive pulmonary disease (RR = 1.9). Among women, cigarette smoking was significantly associated with an increased risk of dying from all causes combined (RR = 1.8), cancer of the lung (RR = 3.6), and peptic ulcer (RR = 17.8). The estimated number of deaths attributable to cigarette smoking in Taiwan in 1994 was 8161 (13.9% of total deaths) for men and 1216 (3.3% of total deaths) for women. In the same year cigarette smoking caused 21.3% and 2.9% of cancer deaths in men and women, respectively, in Taiwan.?CONCLUSIONS—Cigarette smoking has a striking impact on overall mortality and deaths from various causes in the Taiwanese population. Tobacco control should be established as the top priority in public health programmes in Taiwan.???Keywords: mortality; smoking-attributable diseases; Taiwan

Liaw, K.; Chen, C.



Inconvenience due to travelers' diarrhea: a prospective follow-up study  

PubMed Central

Background Limited data exist documenting the degree to which travelers are inconvenienced by travelers' diarrhea (TD). We performed a prospective follow-up study at the travel clinic of Leiden University Medical Center in The Netherlands to determine the degree of inconvenience and to determine how experiencing TD affects travelers' perception. Methods Healthy adults who intended to travel to the (sub)tropics for less than two months were invited to take part. Participants filled out a web-based questionnaire before departure and after returning home. TD was defined as three or more unformed stools during a 24-hour period. Results 390 of 776 Eligible travelers completed both questionnaires. Participants' median age was 31 years and mean travel duration 23 days. Of 160 travelers who contracted TD (incidence proportion 41%, median duration of TD episode 2.5 days) the majority (107/160, 67%) could conduct their activity program as planned despite having diarrhea. However, 21% (33/160) were forced to alter their program and an additional 13% (20/160) were confined to their accommodation for one or more daylight days; 53 travelers (33%) used loperamide and 14 (9%) an antibiotic. Eight travelers (5%) consulted a physician for the diarrheal illness. When asked about the degree of inconvenience brought on by the diarrheal illness, 39% categorized it as minor or none at all, 34% as moderate and 27% as large or severe. In those who regarded the episode of TD a major inconvenience, severity of symptoms was greater and use of treatment and necessity to alter the activity program were more common. Travelers who contracted travelers' diarrhea considered it less of a problem in retrospect than they had thought it would be before departure. Conclusion Conventional definitions of TD encompass many mild cases of TD (in our study at least a third of all cases) for which treatment is unlikely to provide a significant health benefit. By measuring the degree of inconvenience brought on by TD, researchers and policy makers may be able to better distinguish 'significant TD' from mild TD, thus allowing for a more precise estimation of the size of the target population for vaccination or stand-by antibiotic prescription and of the benefit of such measures.



Gamma-knife radiosurgery in acromegaly: a 4-year follow-up study.  


Stereotactic radiosurgery by gamma-knife (GK) is an attractive therapeutic option after failure of microsurgical removal in patients with pituitary adenoma. In these tumors or remnants of them, it aims to obtain the arrest of cell proliferation and hormone hypersecretion using a single precise high dose of ionizing radiation, sparing surrounding structures. The long-term efficacy and toxicity of GK in acromegaly are only partially known. Thirty acromegalic patients (14 women and 16 men) entered a prospective study of GK treatment. Most were surgical failures, whereas in 3 GK was the primary treatment. Imaging of the adenoma and target coordinates identification were obtained by high resolution magnetic resonance imaging. All patients were treated with multiple isocenters (mean, 8; range, 3-11). The 50% isodose was used in 27 patients (90%). The mean margin dose was 20 Gy (range, 15-35), and the dose to the visual pathways was always less than 8 Gy. After a median follow-up of 46 months (range, 9-96), IGF-I fell from 805 micro g/liter (median; interquartile range, 640-994) to 460 micro g/liter (interquartile range, 217-654; P = 0.0002), and normal age-matched IGF-I levels were reached in 7 patients (23%). Mean GH levels decreased from 10 micro g/liter (interquartile range, 6.4-15) to 2.9 micro g/liter (interquartile range, 2-5.3; P < 0.0001), reaching levels below 2.5 micro g/liter in 11 (37%). The rate of persistently pathological hormonal levels was still 70% at 5 yr by Kaplan-Meier analysis. The median volume was 1.43 ml (range, 0.20-3.7). Tumor shrinkage (at least 25% of basal volume) occurred after 24 months (range, 12-36) in 11 of 19 patients (58% of assessable patients). The rate of shrinkage was 79% at 4 yr. In no case was further growth observed. Only 1 patient complained of side-effects (severe headache and nausea immediately after the procedure, with full recovery in a few days with steroid therapy). Anterior pituitary failures were observed in 2 patients, who already had partial hypopituitarism, after 2 and 6 yr, respectively. No patient developed visual deficits. GK is a valid adjunctive tool in the management of acromegaly that controls GH/IGF-I hypersecretion and tumor growth, with shrinkage of adenoma and no recurrence of the disease in the considered observation period and with low acute and chronic toxicity. PMID:12843150

Attanasio, Roberto; Epaminonda, Paolo; Motti, Enrico; Giugni, Enrico; Ventrella, Laura; Cozzi, Renato; Farabola, Mario; Loli, Paola; Beck-Peccoz, Paolo; Arosio, Maura



[Rockwood capsulorrhaphy in shoulder instability. A clinical follow-up study].  


Rockwood described a capsulorrhaphy technique for operative treatment of multidirectional shoulder instability with anterior dislocation. We have used this technique mainly in patients with severe multidirectional instability and now have 8 years' experience with it, which is reported below. The surgical technique involves refixation of the Bankart lesion with transosseous suture and double breasting of the anterior capsule. No transposition of the subcapularis muscle was performed. A functional rehabilitation program without immobilization was used in all patients. The daily activity level, the degree of discomfort upon shoulder-related activities and the subjective assessment of outcome were recorded for each patient. General outcome was determined with reference to Rowe's score. A clinical examination was performed as well as radiography. Strength was evaluated by standardized bilateral dynamometry. Follow-up examination was possible in 73 out of 82 patients. The mean age at follow up was 32.7 +/- 4.1 years, and the mean follow-up time, 4.3 years. The reason for surgery was recurrent dislocation in 81% of patients, pain in 4% and both pain and dislocation in 15% of patients. In 8 patients (10.9%) multiple (up to 4) previous surgical attempts by various methods had been unsuccessful. Postoperatively 59% (n = 44) were able to take part in sports without restrictions, 27.4% could take part only in sports not involving the shoulder, and 13.5% (n = 10) did not engage in any sports postoperatively. The redislocation rate was 12.3% (n = 9), and there was 1 traumatic redislocation. A deficit in abduction/elevation by 10-60 degrees was found in 4 patients (5.4%) and by > 60 degrees in 2 patients (2.7%).(ABSTRACT TRUNCATED AT 250 WORDS) PMID:7610391

Pape, H C; Bosch, U; Lobenhoffer, P; Conrad, B; Maghsudi, M; Tscherne, H



Celiac disease and type I (Insulin-Dependent) diabetes mellitus in childhood: Follow-up study  

Microsoft Academic Search

To ascertain the specificity of IgA and IgG antigliadin (IgA-AGA, IgG-AGA), IgA-antireticulin (R1-ARA), and antiendomysial (AEA) antibodies for the diagnosis of celiac disease, we evaluated 133 type I diabetic children aged 1.4–28.4 years (mean 14.1 ± 6.6), with diabetes from onset to 20.5 years. Fifty-three patients were considered at onset and 49 of these also during follow-up. IgA-AGA and IgG-AGA

Renata Lorini; M. Serenella Scotta; Luigia Cortona; M. Antonietta Avanzini; Letizia Vitali; Costantino De Giacomo; Andrea Scaramuzza; Francesca Severi



Long-term follow-up study of gastroduodenal lesions after radioembolization of hepatic tumors  

PubMed Central

AIM: To evaluate the long-term natural history of the gastroduodenal lesions secondary to extrahepatic embolization with Ytrium 90 (90Y) spheres. METHODS: From September 2003 to January 2012, 379 procedures of liver radioembolization (RE) using resin microspheres loaded with 90Y were performed in our center. We have retrospectively compiled the data from 379 RE procedures performed in our center. We report a comprehensive clinical, analytical, endoscopic and histologic long-term follow-up of a series of patients who developed gastroduodenal lesions after the treatment. RESULTS: Six patients (1.5%) developed gastrointestinal symptoms and had gastrointestinal lesions as shown by upper endoscopy in the next 12 wk after RE. The mean time between RE and the appearance of symptoms was 5 wk. Only one patient required endoscopic and surgical treatment. The incidence of gastrointestinal ulcerations was 3.75% (3/80) when only planar images were used for the pre-treatment evaluation. It was reduced to 1% (3/299) when single-photon emission computed tomography (SPECT) images were also performed. The symptoms that lasted for a longer time were nausea and vomiting, until 25 mo after the treatment. CONCLUSION: All patients were free from severe symptoms at the end of follow-up. The routine use of SPECT has decreased the incidence of gastrointestinal lesions due to unintended deployment of 90Y particles.

Rodriguez-Lago, Iago; Carretero, Cristina; Herraiz, Maite; Subtil, Jose C; Betes, Maite; Rodriguez-Fraile, Macarena; Sola, Jesus J; Bilbao, Jose I; Munoz-Navas, Miguel; Sangro, Bruno



Maintaining Superior Follow-Up Rates in a Longitudinal Study: Experiences from the College Life Study  

PubMed Central

Longitudinal studies are often considered to be a gold standard for research, but the operational management of such studies is not often discussed in detail; this paper describes strategies used to track and maintain high levels of participation in a longitudinal study involving annual personal interviews with a cohort of 1,253 undergraduates (first-time, first-year students at time of enrollment) at a large public mid-Atlantic university.

Vincent, Kathryn B.; Kasperski, Sarah J.; Caldeira, Kimberly M.; Garnier-Dykstra, Laura M.; Pinchevsky, Gillian M.; O'Grady, Kevin E.; Arria, Amelia M.



Calculating Follow-up Rates  

Microsoft Academic Search

Follow-up rates are presented as a percentage but the method of calculation is seldom discussed. Determining a follow-up rate\\u000a begins with identifying the numerator and denominator used in the calculation. Four methods of calculating follow-up rate\\u000a after surgical treatment for weight reduction were studied. Method 1 follow-up rate, 91.2%, was calculated using patients\\u000a with at least one follow-up contact as

Kathleen Renquist; Gary Jeng; Edward E. Mason; NBSR Data Contributors



Fate of Clinical Research Studies after Ethical Approval - Follow-Up of Study Protocols until Publication  

PubMed Central

Background Many clinical studies are ultimately not fully published in peer-reviewed journals. Underreporting of clinical research is wasteful and can result in biased estimates of treatment effect or harm, leading to recommendations that are inappropriate or even dangerous. Methods We assembled a cohort of clinical studies approved 2000–2002 by the Research Ethics Committee of the University of Freiburg, Germany. Published full articles were searched in electronic databases and investigators contacted. Data on study characteristics were extracted from protocols and corresponding publications. We characterized the cohort, quantified its publication outcome and compared protocols and publications for selected aspects. Results Of 917 approved studies, 807 were started and 110 were not, either locally or as a whole. Of the started studies, 576 (71%) were completed according to protocol, 128 (16%) discontinued and 42 (5%) are still ongoing; for 61 (8%) there was no information about their course. We identified 782 full publications corresponding to 419 of the 807 initiated studies; the publication proportion was 52% (95% CI: 0.48–0.55). Study design was not significantly associated with subsequent publication. Multicentre status, international collaboration, large sample size and commercial or non-commercial funding were positively associated with subsequent publication. Commercial funding was mentioned in 203 (48%) protocols and in 205 (49%) of the publications. In most published studies (339; 81%) this information corresponded between protocol and publication. Most studies were published in English (367; 88%); some in German (25; 6%) or both languages (27; 6%). The local investigators were listed as (co-)authors in the publications corresponding to 259 (62%) studies. Conclusion Half of the clinical research conducted at a large German university medical centre remains unpublished; future research is built on an incomplete database. Research resources are likely wasted as neither health care professionals nor patients nor policy makers can use the results when making decisions.

Blumle, Anette; Meerpohl, Joerg J.; Schumacher, Martin; von Elm, Erik




SciTech Connect

Follow-up testing was conducted to better understand the excessive hydrogen generation seen in the initial Sludge Batch 4 (SB4) qualification Sludge Receipt and Adjustment Tank/Slurry Mix Evaporator (SRAT/SME) simulation in the Savannah River National Laboratory (SRNL) Shielded Cells. This effort included both radioactive and simulant work. The initial SB4 qualification test produced 0.59 lbs/hr hydrogen in the SRAT, which was just below the DWPF SRAT limit of 0.65 lbs/hr, and the test produced over 0.5 lbs/hr hydrogen in the SME cycle on two separate occasions, which were over the DWPF SME limit of 0.223 lbs/hr.

Pareizs, J; David Koopman, D; Dan Lambert, D; Cj Bannochie, C



Maxillonasal dysplasia (Binder's syndrome) and its treatment with costal cartilage graft: A follow-up study  

PubMed Central

Maxillonasal dysplasia or Binder's syndrome is an uncommon congenital condition characterized by a retruded mid-face with an extremely flat nose. We report here six patients with maxillonasal dysplasia whose noses were corrected with onlay costal cartilage grafts using a combined oral vestibular and external rhinoplasty approach for nasal dorsal augmentation, columellar lengthening, and premaxillary augmentation. The cartilage graft was dipped in a solution of 100 ml 0.9% NaCl and one vial (80mg) gentamicin for 30 min to prevent warping. L struts made for nasal augmentation, columellar lengthening, and premaxillary augmentation were fixed to one another by slots made in the graft. This technique has been used in children, adults, and for secondary cases with promising results. All patients were of class I dental occlusion. The nasal and premaxillary augmentation which was monitored by serial photography was found to be stable over a follow-up period of three years.

Bhatt, Yogesh C.; Vyas, Kinnari A.; Tandale, Mangesh S.; Panse, Nikhil S.; Bakshi, Harpreet S.; Srivastava, Rajat K.



Anemia after gastrectomy for early gastric cancer: Long-term follow-up observational study  

PubMed Central

AIM: To identify the incidence and etiology of anemia after gastrectomy in patients with long-term follow-up after gastrectomy for early gastric cancer. METHODS: The medical records of those patients with early gastric adenocarcinoma who underwent curative gastrectomy between January 2006 and October 2007 were reviewed. Patients with anemia in the preoperative workup, cancer recurrence, undergoing systemic chemotherapy, with other medical conditions that can cause anemia, or treated during follow up with red cell transfusions or supplements for anemia were excluded. Anemia was defined by World Health Organization criteria (Hb < 12 g/dL in women and < 13 g/dL in men). Iron deficiency was defined as serum ferritin < 20 ?g/dL. Vitamin B12 deficiency was defined as serum vitamin B12 < 200 pg/mL. Iron deficiency anemia was defined as anemia with concomitant iron deficiency. Anemia from vitamin B12 deficiency was defined as megaloblastic anemia (mean cell volume > 100 fL) with vitamin B12 deficiency. The profile of anemia over 48 mo of follow-up was analyzed. RESULTS: One hundred sixty-one patients with gastrectomy for early gastric cancer were analyzed. The incidence of anemia was 24.5% at 3 mo after surgery and increased up to 37.1% at 48 mo after surgery. The incidence of iron deficiency anemia increased during the follow up and became the major cause of anemia at 48 mo after surgery. Anemia of chronic disease and megaloblastic anemia were uncommon. The incidence of anemia in female patients was significantly higher than in male patients at 12 (40.0% vs 22.0%, P = 0.033), 24 (45.0% vs 25.0%, P = 0.023), 36 (55.0% vs 28.0%, P = 0.004), and 48 mo (52.0% vs 31.0%, P = 0.022) after surgery. Patients with total gastrectomy showed significantly higher incidence of anemia than patients with subtotal gastrectomy at 48 mo after surgery (60.7% vs 31.3%, P = 0.008). The incidence of iron deficiency was significantly higher in female patients than in male patients at 6 (35.4% vs 13.3%, P = 0.002), 12 (45.8% vs 16.8%, P < 0.001), 18 (52.1% vs 22.3%, P < 0.001), 24 (60.4% vs 20.9%, P < 0.001), 36 (62.5% vs 29.2%, P < 0.001), and 48 mo (66.7% vs 34.7%, P = 0.001) after surgery. CONCLUSION: Anemia was frequent after gastrectomy for early gastric cancer, with iron deficiency being the major cause. Evaluation for anemia including iron status should be performed after gastrectomy and appropriate iron replacement should be considered.

Lim, Chul-Hyun; Kim, Sang Woo; Kim, Won Chul; Kim, Jin Soo; Cho, Yu Kyung; Park, Jae Myung; Lee, In Seok; Choi, Myung-Gyu; Song, Kyo-Young; Jeon, Hae Myung; Park, Cho-Hyun



Epigenome-wide DNA methylation changes with development of arsenic-induced skin lesions in Bangladesh: a case-control follow-up study  

PubMed Central

Studies have found an association between aberrant DNA methylation and arsenic-induced skin lesions. Yet, little is known about DNA methylation changes over time in people who develop arsenic-induced skin lesions. We sought to investigate epigenome-wide changes of DNA methylation in people who developed arsenic-induced skin lesions in a ten year period. In 2009–2011, we conducted a follow-up study of 900 skin lesion cases and 900 controls and identified 10 people who developed skin lesions since a baseline survey in 2001–2003. The 10 cases (“New Cases”) were matched with 10 controls who did not have skin lesions at baseline or follow-up (“Persistent Controls”). Drinking water and blood samples were collected and skin lesion was diagnosed by the same physician at both time points. We measured DNA methylation in blood using Infinium HumanMethylation450K BeadChip, followed by quantitative validation using pyrosequencing. Two-sample t-tests were used to compare changes in percent methylation between New Cases and Persistent Controls. Six CpG sites with greatest changes of DNA methylation over time among New Cases were further validated with a correlation of 93% using pyrosequencing. One of the validated CpG site (cg03333116; change of %methylation was 13.2 in New Cases versus ?0.09 in Persistent Controls; P <0.001) belonged to the RHBDF1 gene, which was previously reported to be hypermethylated in arsenic-exposed cases. We examined DNA methylation changes with the development of arsenic-induced skin lesions over time but nothing was statistically significant given the small sample size of this exploratory study and the high dimensionality of data.

Seow, Wei Jie; Kile, Molly L.; Baccarelli, Andrea A.; Pan, Wen-Chi; Byun, Hyang-Min; Mostofa, Golam; Quamruzzaman, Quazi; Rahman, Mahmuder; Lin, Xihong; Christiani, David C.



Follow-up study of patients with contact dermatitis caused by chromates, nickel, and cobalt.  


The patch test results from 1,000 patients tested with the ICDRG standard series are analyzed for positive reactions to potassium dichromate, nickel sulphate, and cobalt chloride. Nickel appears to be the most common sensitizer, especially among women, although false-negative reactions may occur if it is tested with a 2.5% concentration in yellow petrolatum. Chromate dermatitis is generally of occupational origin among men. It is also quite common among Belgian women, probably because of the widespread use of Javel (liquid bleach), containing sodium dichromate as a colouring and stabilizing agent. Positive patch test reactions to cobalt are generally accompanied by allergic reactions to nickel or chromate. Its role as a primary allergen, however, must never be overlooked. The relationship between these metals and hand and foot eczema is evaluated. The results of a follow-up questionnaire are given. More than 70% of the patients allergic to chromates or nickel continued to suffer from contact eczema after the diagnosis had been made and therapeutic measures taken. PMID:7358190

Dooms-Goossens, A; Ceuterick, A; Vanmaele, N; Degreef, H



Reproducible measurements based on myocardial perfusion studies for patient follow-up  

NASA Astrophysics Data System (ADS)

Our aim is to derive quantitative measurements from Myocardium Perfusion Scintigraphic (MPS) exams for drug trials on Myocardium re-perfusion. We are considering 19 patients imaged 6 times to measure the effects of various conditions of SPECT acquisition (Sestamibi stress and Thallium rest). We are also measuring the stability of various indices of perfusion evolution. Our method is based on intra-patients image matching techniques for follow-up and on inter-patients matching with a reference model based on 100 normal subjects to define perfusion abnormalities. We are measuring intensity differences between normalized images of 10% for Sestamibi and 14% for Thallium. Correlation between image acquisitions is 95% for Sestamibi and 88% for Thallium. Our most stable index is the deficit load, being the integral over stress defects of perfusion deficit. For our 19 cases, deficit load average is 8% of global normal perfusion (GNP), standard deviation between 2 acquisitions is about 0.5% GNP with a -0.4% GNP systematic bias, and correlation between 2 acquisitions is 99.8%. The stability of the index is demonstrated and we expect that a deficit load variation of more than 2% GNP is significant of an evolution, which has to be confirmed by ongoing retrospective drug trials.

Thirion, Jean-Philippe; Leonard, Scott; Hendel, Robert



Risk Factors for Congestive Heart Failure in US Men and Women NHANES I Epidemiologic Follow-up Study  

Microsoft Academic Search

Background: The incidence of congestive heart fail- ure (CHF) has been increasing steadily in the United States during the past 2 decades. We studied risk factors for CHF and their corresponding attributable risk in the First National Health and Nutrition Examination Survey Epi- demiologic Follow-up Study. Participants and Methods: A total of 13643 men and women without a history of

Jiang He; Lorraine G. Ogden; Lydia A. Bazzano; Suma Vupputuri; Catherine Loria; Paul K. Whelton



1990 Follow-up of Former JCCC Students Currently Enrolled at Four-Year Colleges or Universities: A Transfer Study.  

ERIC Educational Resources Information Center

In 1990, a follow-up study was conducted of former Johnson County Community College (JCCC) students who transferred to four-year colleges and universities during 1989. The study sought to provide information concerning JCCC's role in preparing students for transfer, assess students' perceptions of their educational experiences at JCCC, and gather…

Johnson County Community Coll., Overland Park, KS. Office of Institutional Research.


Staff, School and Workshop Characteristics Affecting Continued Use and Adaptation of Knowledge: A Follow-Up Study.  

ERIC Educational Resources Information Center

Current research and past experience indicate the need to examine longitudinal effects of staff development efforts on school improvement and knowledge use. A six-month follow-up study of knowledge use from staff inservice training was undertaken. Questionnaries were completed by 235 staff (94 percent teachers) who had participated in a study of…

Rappa, Joseph B.; And Others


The Effectiveness of Written Recasts in the Second Language Acquisition of Aspectual Distinctions in French: A Follow-Up Study  

ERIC Educational Resources Information Center

This follow-up study on the acquisition of the aspectual distinction between the pass compos (PC) and the imparfait (IMP) investigates the differential outcomes of the results presented in an earlier study, Ayoun (2001), by pursuing two lines of research: the effectiveness of written recasts versus models and traditional grammar instruction, and…

Ayoun, Dalila



Ensuring Retention in Longitudinal Studies: A Practical Evaluation of an Intensive Follow-up Protocol and Suggested Adaptations  

PubMed Central

Ensuring retention in longitudinal studies of individuals with substance use disorders (SUD) is a continual challenge for researchers. This study made several modifications to a highly intensive follow-up protocol (Scott, 2004), originally designed for adults with SUD, in order to adapt it to a group of adolescents in low-intensity outpatient SUD treatment (N = 127, M age 16.7 yrs) and to accommodate limitations in the financial resources available for study staffing and transportation. In the present sample, adolescent participants generally found it unreasonable for study staff to request to contact people outside their immediate family in order to locate them and to attempt to schedule interviews 3–6 months in advance, as specified in the original protocol. Changes were made to accommodate these concerns and follow-up rates remained high (85–91%). Even though this study is limited by its non-experimental nature, it provides a replicable example of a scaled-down, less costly version of a highly intensive follow-up protocol that can be used to achieve high follow-up rates in studies of adolescents with SUD. We hope this will be encouraging for researchers and program evaluators who have limited resources or who work with participants who express concerns about privacy or study burden.

Yeterian, Julie D.; Dow, Sarah J.; Kelly, John F.



Intracranial Pressure and Biochemical Indicators of Brain Damage: Follow-up Study  

PubMed Central

Aim To investigate the relation between metabolic parameters of the brain tissue, as direct indicators of real metabolic conditions within the brain, and intracranial pressure, as the consequence of pathophysiological changes. Methods Twelve patients with closed head injuries were followed up for 24 hours after injury. A Codman parenchymal intracranial pressure and a Neurotrend electrode were inserted within 3 hours after injury to monitor parenchymal intracranial pressure, brain tissue partial oxygen pressure (PbrO2), brain tissue partial carbon dioxide pressure (PbrCO2), pH, and brain tissue temperature. Data detected at 8-hourly intervals were compared with repeated measures analysis of variance. Result At the initial observation, the mean value of intracranial pressure was 22.2?±?3.2 mm Hg. Although it increased at the second and decreased at the third measurement, the differences between the measurements were not significant (P?=?0.320). The value of PbrCO2 was increased from the beginning (63.3?±?6.0 mm Hg), whereas PbrO2 was within the normal range at the first measurement (38.9?±?6.9 mm Hg), but significantly decreased after 8 hours (P?=?0.004), remaining low at later time points. Conclusion After brain injury, changes in PbrCO2 are visible earlier than those in PbrO2. Improvement in intracranial pressure values did not necessary mean improvement in the brain tissue oxygenation. In addition to intracranial pressure, PbrO2, PbrCO2 and pH should also be monitored, as they directly reflect the real metabolic conditions within brain tissue and may be used in predictions about the outcome and possible therapeutic approaches.

Korsic, Marjan; Jugovic, Domagoj; Kremzar, Boriana



Adherence to Antiretroviral Therapy in Jinja, Uganda: A Six-Year Follow-Up Study  

PubMed Central

Introduction We report on the adherence experience of a group of people living with HIV on ART over six years in Uganda. Methods Between 2005 and 2009, we followed up 41 participants who were also part of a clinical trial comparing home and facility based delivery of ART in Jinja, eastern Uganda. We conducted qualitative in-depth interviews at enrolment, 3, 6, 18 and 30 months to capture experiences with adherence over time. In 2011 we returned to these participants to find out how they were fairing with long term adherence. We managed to retrace 24 participants and interviewed them about their experience. We thematically analysed the data and compared findings over time. Results Initially there were few barriers to adherence and many followed the adherence guidance closely. By year six, relaxation of these rules was noticeable although self-reported adherence continued to be high. Alcohol consumption was more common than before. Some relatives of the participants who had died claimed that some deaths were a result of alcohol. While participants reported that ART had allowed them to reclaim independence and return to work the changes in work and social routines created new challenges for adherence. Side effects like lipodystrophy were not only causing some stigma but for some tested their faith in the drugs. Many participants reported resumption of sexual lives but apart from those who selected same status partners, disclosure to new partners was minimal. Conclusion Good adherence practice to ART wanes over the long-term, and people who may have disclosed at initiation find it difficult to do so to new partners once they are healthy. Further adherence interventions and support with disclosure over the course of therapy may need to be considered. (Words: 283)

Mbonye, Martin; Seeley, Janet; Ssembajja, Fatuma; Birungi, Josephine; Jaffar, Shabbar



[The course of nursing home admission. A follow-up study in chronic and rehabilitation patients].  


This article describes the course of the nursing home stays of 157 newly admitted patients (55 years and older) using the Behaviour Rating Scale for Elderly Patients ('Beoordelingsschaal Oudere Patiënten'). The follow-up period lasted maximally one year. Differences in the course in relation to the objective of the admission (rehabilitation versus continuous support) and possible factors which impeded or advanced the discharge of the rehabilitation patients, were investigated. For that purpose, information on diagnoses, prognosis, treatment goals and their achievement, and disability according to SIVIS (SIG Nursing Home Information System) was also obtained from the physicians in charge at the nursing home. The course of the nursing home stay appeared to differ for chronic and rehabilitation patients. In addition to physical disability and depressive behavior, the chronic patients, from the time of admission onwards, had more behavioural problems than the rehabilitation patients. Moreover, their dependency, physical and mental disability and inactivity increased in different degree during the stay. For two thirds of the rehabilitation patients, the stay did not end in discharge from the nursing home. For this group, the dependency, depressive behaviour, and to a lesser extent, aggressiveness increased during the stay. The outcome of rehabilitation appeared to be related to the extent of behavioural problems, to the level of disability, and to the medical condition on admission. The least disabled and the 'medically least complex' patients could usually be discharged with an improved level of functioning, which seemed to justify the nursing home stay. The absence of other services impeded discharge in a few cases.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:1609446

te Wierik, M J; Frederiks, C M; Visser, A P; Sturmans, F



Using Facebook to Maximize Follow-Up Response Rates in a Longitudinal Study of Adults Who Use Methamphetamine  

PubMed Central

This study examines the process and effects of using facebook (FB) to locate and re-contact study participants targeted for follow up in a longitudinal study of adult methamphetamine users (N = 649). A follow-up interview was conducted in 2009–11 approximately 8 years after previous study participation. Our paper describes re-contact efforts involving FB, including IRB regulatory issues and the effectiveness of using FB compared to mailings and phone calls. A total of 48 of the 551 surviving non-incarcerated participants who agreed to be contacted for follow up studies were contacted via FB, of whom 11 completed the follow-up interview. Those contacted through FB were more likely to be younger, female, relocated out-of-state, and reported somewhat higher rates of anxiety and cognitive problems compared to those not located on FB. Although participants contacted through FB are likely to differ demographically from those contacted by phone or mail, FB provides a potentially effective means to expand conventional methods of correspondence for contacting hard to reach participants.

Bolanos, Franklin; Herbeck, Diane; Christou, Dayna; Lovinger, Katherine; Pham, Aurora; Raihan, Adnan; Rodriguez, Luz; Sheaff, Patricia; Brecht, Mary-Lynn



Life Satisfaction, Illness Behaviour, and Rehabilitation Outcome: Results of a One Year Follow-Up Study with Cardiac Patients.  

ERIC Educational Resources Information Center

Follow-up study one year after an inpatient cardiac rehabilitation program of 83 male cardiac patients found reported life satisfaction generally lower with increased physical complaints and emotional lability. Of patients originally identified as having high life satisfaction, 90 percent were back at work compared to 66 percent of patients with…

Myrtek, Michael



A 3-Year Early Home Intervention Follow-Up Study with Low Birthweight Infants and Their Parents.  

ERIC Educational Resources Information Center

This follow-up study of low birthweight children at the age of 4-5 found that 14 control children (who did not participate in early home intervention) scored lower than 31 preterm treatment children and 22 full-term controls on expressive language, comprehension, personal-social skills, visual-motor skills, and home environment. (Author/JDD)

Barrera, Maria E.; And Others



A Follow-Up Study of One Group of Achievers and Underachievers Four Years after High School Graduation.  

ERIC Educational Resources Information Center

A four-year follow-up study comparing 73 gifted achievers and underachievers found all achievers attended college, were more sure of career directions, completed more years of college, and were more involved in campus activities, but did not report more satisfaction with life development since high school than underachievers. (Contains…

Peterson, Jean Sunde



Methods and Measures Used for Follow-up at 15 Years of the English and Romanian Adoptee (ERA) Study  

ERIC Educational Resources Information Center

This chapter covers the methods and measures used in the ERA study, with a special focus on age 15 outcomes. First, the authors outline the sample participation rate for the 15-year follow-up--the percentages in all cases referring to the numbers at the time of initial sample contact. They then describe the measures used in this monograph,…

Monographs of the Society for Research in Child Development, 2010



Adolescents With Gender Identity Disorder Who Were Accepted or Rejected for Sex Reassignment Surgery: A Prospective Follow-up Study  

Microsoft Academic Search

ObjectiveTo conduct a prospective follow-up study with 20 treated adolescent transsexuals to evaluate early sex reassignment, and with 21 nontreated and 6 delayed-treatment adolescents to evaluate the decisions not to allow them to start sex reassignment at all or at an early age.




Skin cancer in patients with psoriasis treated with coal tar. A 25-year follow-up study  

Microsoft Academic Search

For many years, crude coal tar has been used for the treatment of psoriasis. The possible carcinogenic effect of crude coal tar and ultraviolet (UV) radiation (Goeckerman regimen), considered individually or in combination, has been of some concern to physicians. A 25-year follow-up study was completed on 280 patients with psoriasis who were hospitalized and treated with crude coal tar

M. R. Pittelkow; H. O. Perry; S. A. Muller; W. Z. Maughan; P. C. OBrien



Follow-up study of disability among elderly patients discharged from hospital with exacerbations of chronic bronchitis  

Microsoft Academic Search

Chronic bronchitis is a common reason for admitting an old person to hospital. Government statistics measure the impact of admission only in terms of mortality. A follow-up study of disability among the elderly admitted to hospital wih an exacerbation of chronic bronchitis is described. One month after discharge about 30% of patients were unable to walk as far on the

H Peach; M S Pathy



Occupational Physical Activity, Overweight, and Mortality: A Follow-Up Study of 47,405 Norwegian Women and Men  

ERIC Educational Resources Information Center

This population-based 24-year follow-up study evaluated the association of occupational physical activity (OPA) with overweight and mortality in 47,405 men and women, healthy at baseline, and reporting OPA as sedentary (reference), light, moderately heavy, or heavy. The adjusted odds ratio for overweight was slightly less than 1 for all categories…

Graff-Iversen, Sidsel; Selmer, Randi; Sorensen, Marit; Skurtveit, Svetlana



Developmental quotient at 24 months and fatty acid composition of diet in early infancy: a follow up study  

Microsoft Academic Search

AIMA follow up study of developmental quotient (DQ) at 24 months of toddlers whose diets in early infancy differed in fatty acid composition, and in whom an association between diet and DQ was observed at 4 months.METHODS81 toddlers were distributed among three groups according to early type of diet: standard infant formula (SFo, n = 30); long chain polyunsaturated fatty

Carlo Agostoni; Sabina Trojan; Roberto Bellù; Enrica Riva; Maria Grazia Bruzzese; Marcello Giovannini



A genome scan and follow-up study identify a bipolar disorder susceptibility locus on chromosome 1q42  

Microsoft Academic Search

In this study, we report a genome scan for psychiatric disease susceptibility loci in 13 Scottish families. We follow up one of the linkage peaks on chromosome 1q in a substantially larger sample of 22 families affected by schizophrenia (SCZ) or bipolar affective disorder (BPAD). To minimise the effect of genetic heterogeneity, we collected mainly large extended families (average family

S Macgregor; P M Visscher; S A Knott; P Thomson; D J Porteous; J K Millar; R S Devon; D Blackwood; W J Muir



A Five Year Follow-Up Study of the Nebraska Project: Still a Long Way To Go...  

ERIC Educational Resources Information Center

This pilot study followed up 18 students identified as potentially gifted in 1992 using the Nebraska Project's teacher observation protocol. Results indicated a continued use of traditional identification practices in school districts and the presence of underachieving behaviors in students identified as potentially gifted in 1992 but not…

Han, Ki-Soon; Marvin, Christine



Project TALENT Five-Year Follow-Up Studies, Predicting Development of Young Adults. Interim Report 5.  

ERIC Educational Resources Information Center

The primary purpose of this monograph is to describe the relationship between adolescent personality and the educational and vocational development of young adults, criteria for the latter being developed from the Project TALENT follow-up studies. This relationship seeking is set in a context of career development theory and a concern for guidance…

Cooley, William W.; Lohnes, Paul R.


Photorefractive keratectomy in patients with mild to moderate stable keratoconus: a five-year prospective follow-up study  

PubMed Central

Background The purpose of this study was to evaluate the visual outcome of photorefractive keratectomy (PRK) in patients with mild to moderate stable keratoconus and to assess the risk of progression of the disease after the excimer laser procedure. Methods In this prospective study, carried out at the Clemenceau Medical Center, an affiliate of Johns Hopkins International, in Beirut, Lebanon, 119 eyes from 72 patients with grade 1–2 keratoconus (Amsler–Krumeich classification) underwent PRK. Forty-seven patients had both eyes treated and 25 patients had one eye treated. The procedure was done using the Wavelight Eye Q Excimer laser. Uncorrected and best-corrected visual acuity, corneal topography, and pachymetry were assessed before the procedure and 3, 6, 12, 36, and 60 months after the procedure. Results Mean uncorrected visual acuity showed a statistically significant improvement (P < 0.05) at one, 3, and 5 years follow-up. One hundred and seventeen eyes (98.3%) showed no progression while two eyes (1.7%) showed progression of the disease at 5 years follow-up, as documented by corneal topography and pachymetry. These two eyes were treated with corneal collagen crosslinking. Conclusion PRK in mild to moderate keratoconus is a safe and effective procedure for improving uncorrected vision in patients with mild refractive errors. However, close follow-up of patients is needed to detect any progression of the disease. Longer follow-up is needed to assess the overall effect of this procedure on progression of the disease.

Chelala, Elias; Rami, Hala El; Dirani, Ali; Fadlallah, Ali; Fakhoury, Omar; Warrak, Elias



Barriers and facilitators for participation in health promotion programs among employees: a six-month follow-up study  

PubMed Central

Background Health promotion programs (HPPs) are thought to improve health behavior and health, and their effectiveness is increasingly being studied. However, participation in HPPs is usually modest and effect sizes are often small. This study aims to (1) gain insight into the degree of participation of employees in HPPs, and (2) identify factors among employees that are associated with both their intention to participate and actual participation in HPPs. Methods Employees of two organizations were invited to participate in a six-month follow-up study (n?=?744). Using questionnaires, information on participation in HPPs was collected in two categories: employees’ intention at baseline to participate and their actual participation in a HPP during the follow-up period. The following potential determinants were assessed at baseline: social-cognitive factors, perceived barriers and facilitators, beliefs about health at work, health behaviors, and self-perceived health. Logistic regression analyses, adjusted for demographics and organization, were used to examine associations between potential determinants and intention to participate, and to examine the effect of these determinants on actual participation during follow-up. Results At baseline, 195 employees (26%) expressed a positive intention towards participation in a HPP. During six months of follow-up, 83 employees (11%) actually participated. Participants positively inclined at baseline to participate in a HPP were more likely to actually participate (OR = 3.02, 95% CI: 1.88-4.83). Privacy-related barriers, facilitators, beliefs about health at work, social-cognitive factors, and poor self-perceived health status were significantly associated with intention to participate. The odds of employees actually participating in a HPP were higher among participants who at baseline perceived participation to be expected by their colleagues and supervisor (OR = 2.87, 95% CI: 1.17-7.02) and among those who said they found participation important (OR = 2.81, 95% CI: 1.76-4.49). Conclusions Participation in HPPs among employees is limited. Intention to participate predicted actual participation in a HPP after six months of follow-up. However, only 21% of employees with a positive intention actually participated during follow-up. Barriers, facilitators, beliefs about health at work, social-cognitive factors, and a poor self-perceived health status were associated with intention to participate, but hardly influenced actual participation during follow-up.



Axillofemoral bypass: a ten-year review.  

PubMed Central

During a ten-year period (1969-1980), 106 grafts were implanted in the axillofemoral and axillobifemoral positions. This retrospective study is based on life table analysis of cumulative patency rates in both axillofemoral and axillobifemoral grafts, with and without thrombectomy. Dacron grafts were used exclusively from 1969 to 1979, and PTFE from 1979 to 1980. Cumulative patency for Dacron axillobifemoral grafts was 97 +/- 3% at 32 months (73 +/- 21% at 42 months). Patency in both unilateral and bifemoral grafts was significantly increased by thrombectomy. Dacron and PTFE axillobifemoral graft patency was not significantly different. Perioperative mortality was 8% in a group of patients whose survival rate at four years was only 50 +/- 10% from associated disease. Axillobifemoral grafting presents an alternative to aortoiliac reconstruction in elderly patients with severe associated disease in whom the risk of anatomic bypass is prohibitive.

Burrell, M J; Wheeler, J R; Gregory, R T; Synder, S O; Gayle, R G; Mason, M S



Introduction: Spitzer -- The Next Ten Years  

NASA Astrophysics Data System (ADS)

NASA's Spitzer Space Telescope passed its ten-year launch anniversary in August 2013 marking a decade of exciting, ground-breaking infrared science programs. The observatory excels at observations aimed at characterizing exoplanets, brown dwarf weather, and studies of the high-redshift universe, and continues to support programs across a wide spectrum of astrophysical disciplines. The science synergy with other NASA missions continues to be outstanding. The current engineering assessment shows that Spitzer can continue operations into at least 2017. The talks in this special session highlight the current state of the art of Spitzer science programs in the fields of high-redshift galaxies, high-redshift clusters, exoplanets, and stellar variability. The speakers will also look to the future when Spitzer will have ceased to operate but will continue to have a substantial scientific impact.

Storrie-Lombardi, Lisa J.



Long-term outcomes of continuous intrathecal baclofen infusion for treatment of spasticity: a prospective multicenter follow-up study.  


Long-term outcomes of 115 patients treated with continuous intrathecal baclofen infusion are reported. A prospective follow-up study was conducted in eight centers. Patients were followed up over a 12-month period. The follow-up scores on the three spasticity scales (Ashworth, spasm, and clonus scales) were significantly lower at every follow-up visit in comparison to the intake score, except for the clonus scale scores at 12 months. Improvements in health-related quality of life (EQ-5D) and functionality (SIP-68, functional independence measure) were small and nonsignificant. A significant reduction in severity of self-reported personal problems rating scale was observed. Sixty-six patients had no adverse events. Types of adverse events reported were wound complications (22%), catheter problems (36%), cerebrospinal fluid leakage (25%), and other complications (17%). Intrathecal baclofen reduces spasticity and severity of patient-reported problems but its effect on quality of life and functionality is less apparent. Improvements are desired in selection criteria, design of spinal catheters, and outcome scales. PMID:22151100

Delhaas, Elmar M; Beersen, Nicoline; Redekop, W Ken; Klazinga, Niek S



Case study: periodic follow-up is necessary in morphea profunda to identify systemic evolution.  


The term "morphea" includes a wide spectrum of clinical entities, varying from localized plaques of only cosmetic importance to deep lesions resulting in considerable morbidity for the patient. In fact, although survival rates are no different from that of the general population, localized scleroderma may be associated with development of substantial disability, as occurs in deep morphea and in pediatric patients (disabling pansclerotic morphea of children). We report a case of morphea profunda affecting a young man with severe, rapidly progressive, widespread skin involvement and focus on the eventual systemic evolution of such cases. A 40-year-old man was admitted in 2002 for progressive subcutaneous indurations, preferentially involving the right side of the trunk. His health was altogether good, with the exception of a beginning chronic obstructive bronchopneumopathy. There was no family or personal history of dysmetabolic, cardiovascular, neoplastic, or cutaneous disease. Three years earlier, the patient had noted the appearance of two infiltrated, intensely red lesions on the right laterocervical and paraumbilical regions. These had been interpreted as subcutaneous lipomatosis on the basis of an ultrasound scan. The lesions had become progressively larger, while their surface had assumed a scleroatrophic appearance. Thereafter, other lesions had developed on his chest and lower limbs, mostly distributed on the right side of the body. Clinical examination revealed well demarcated, depressed sclerotic plaques with ivory-colored centers and erythematous borders ("lilac ring") localized on the neck, chest, and lower abdomen and limbs (Figure 1). They were bound to the deeper structures and arranged in a band-like linear distribution on the right side of the chest and abdomen where they extended horizontally for more than 10 cm in diameter. These lesions were totally asymptomatic. In addition, arborizing telangiectasias were evident on the neck and upper chest (Figure 2). Laboratory investigations provided normal range of erythrocyte sedimentation rat and C reactive protein levels and other inflammation markers. Antinuclear antibody, antidouble-strand DNA, antimitochondrial, anti-extractable antigens (anti-centromere, anti-Scl-70, anti-U1RNP), and anti-Borrelia burgdorferi antibodies were negative. Circulating immunocomplexes binding C1q were substantially increased. Oesophageal x-rays and lower limb electromyography were within normal limits; ventilatory function testing revealed a mild obstruction consistent with the beginning of chronic obstructive pulmonary disease. Although nailfold capillaroscopy documented nonspecific findings of connective tissue disease (mega-capillaries, segmentary dilatation and destruction), the laser-Doppler flussimetry revealed few signs of microcirculatory abnormalities, in absence of Raynaud's phenomenon. An abdominal wall ultrasonography, performed on a sclerotic plaque, documented thinning of the subcutaneous tissue, with increase of the fibrous component and lower fascia and muscle retraction. The biopsy specimen from the abdominal region included fascia and the subcutaneous tissue (previously obtained from the lower abdomen) with epidermal atrophy, a thickening and homogenization of collagen bundles in the deep dermis and hair reduction. A perivascular lympho-monocytic and plasmacellular infiltration with a dermo-epidermal distribution was present. Moreover, septal fibrosis with a perivascular lymphoplasmacellular inflammatory infiltrate was documented within the abdominal rectus muscle. The diagnosis of morphea profunda was made on the basis of clinical and histopathological findings. A therapeutic regimen based on amino benzoic potassium (Potaba; Glenwood, LLC, Glenwood, NJ), oral prednisone, and topical clobetasol was started. After several months of follow-up, the patient had obtained only moderate improvement of the clinical findings. PMID:15891259

Melani, Lucilla; Cardinali, Carla; Giomi, Barbara; Schincaglia, Emiliano; Caproni, Marzia; Fabbri, Paolo



Long-Term Survival after Stroke: 30 Years of Follow-Up in a Cohort, the Copenhagen City Heart Study  

Microsoft Academic Search

Background and Purpose: Only few have studied long-term survival after stroke. Such knowledge is essential for the evaluation of the current and future burden of stroke. The present study presents up to 30 years of follow-up of patients after a first-ever stroke. Methods: Participants in the Copenhagen City Heart Study who experienced a first-ever stroke from 1978 to the end

Gudrun Boysen; Jacob Louis Marott; Morten Grønbæk; Houry Hassanpour; Thomas Truelsen



Prevention of ulcer recurrence after eradication of Helicobacter pylori: A prospective long-term follow-up study  

Microsoft Academic Search

BACKGROUND & AIMS: Short-term follow-up studies show lower relapse rates of duodenal and gastric ulcers after successful Helicobacter pylori eradication. The aim of this study was to determine the long- term outcome of ulcer disease after successful H. pylori eradication.METHODS: We prospectively studied the long-term effect of H. pylori eradication on ulcer recurrence rates in patients after endoscopically proven healing

RW Van der Hulst; E. A. J. Rauws; B. Koycu; J. J. Keller; M. J. Bruno; J. G. P. Tijssen; G. N. J. Tytgat



Service Utilization and Cost of Community Care for Discharged State Hospital Patients: A 3Year Follow-Up Study  

Microsoft Academic Search

Objective: This study examined the mental health service utilization and costs of 321 discharged state hospital patients during a 3-year follow-up period compared with costs if the patients had remained in the hospital. Method: The study subjects were long-stay pa- tients discharged from Philadelphia State Hospital after 1988. A longitudinal integrated da- tabase on all mental health and medical services

Aileen B. Rothbard; Eri Kuno; Arie P. Schinnar; Trevor R. Hadley; Roland Turk


Family burden and coping strategies in schizophrenia: 1-year follow-up data from the BIOMED I study  

Microsoft Academic Search

Background: To date, only few data are available on how family burden in schizophrenia changes over time. In addition, no study has\\u000a explored how such factors as coping styles and social support influence burden over time. This paper presents the 1-year follow-up\\u000a data from the BIOMED I study on family burden and coping strategies in schizophrenia. Methods: A sample of

L. Magliano; G. Fadden; M. Economou; T. Held; M. Xavier; M. Guarneri; C. Malangone; C. Marasco; M. Maj



Parental Subfecundity and Risk of Decreased Semen Quality in the Male Offspring: A Follow-up Study  

Microsoft Academic Search

A few studies have found poor semen quality in sons whose mothers have received fertility treatment, but it is unknown whether the poor semen quality is related to the infertility treatment or to infertility per se, for example, whether it is caused by hereditable factors. Using data from a population-based, Danish follow-up study con- ducted in 2005-2006, the authors of

C. H. Ramlau-Hansen; A. M. Thulstrup; J. Olsen; J. P. Bonde



Risk factors for suicide in young people suffering from schizophrenia: a long-term follow-up study  

Microsoft Academic Search

Ten per cent of patients with schizophrenia commit suicide, but assessment of risk is difficult. Large case–control studies with a long follow-up period are needed. These should focus on patients from one age group to give clinicians the details required to identify those at highest risk.We present a case–control study of 63 patients who committed suicide and 63 controls from

Marc De Hert; Kwame McKenzie; Jozef Peuskens



Breast Cancer Risk Assessed by Anthropometry in the NHANES I Epidemiológica! Follow-up Study  

Microsoft Academic Search

We examined the relation of anthropométrie variables and breast cancer risk in the Epidemiológica! Follow-up Study of the first National Health and Nutrition Examination Survey, a cohort study based on a sample of the United States population. A total of 7149 women, 25 to 74 years of age, who were examined during the period 1971 through 1975 were included in

Christine A. Swanson; D. Yvonne Jones; Arthur Schatzkin; Louise A. Brinton; Regina G. Ziegler



Genetic determinants of long-term changes in blood lipid concentrations: 10-year follow-up of the GLACIER study.  


Recent genome-wide meta-analyses identified 157 loci associated with cross-sectional lipid traits. Here we tested whether these loci associate (singly and in trait-specific genetic risk scores [GRS]) with longitudinal changes in total cholesterol (TC) and triglyceride (TG) levels in a population-based prospective cohort from Northern Sweden (the GLACIER Study). We sought replication in a southern Swedish cohort (the MDC Study; N = 2,943). GLACIER Study participants (N = 6,064) were genotyped with the MetaboChip array. Up to 3,495 participants had 10-yr follow-up data available in the GLACIER Study. The TC- and TG-specific GRSs were strongly associated with change in lipid levels (? = 0.02 mmol/l per effect allele per decade follow-up, P = 2.0 × 10(-11) for TC; ? = 0.02 mmol/l per effect allele per decade follow-up, P = 5.0 × 10(-5) for TG). In individual SNP analysis, one TC locus, apolipoprotein E (APOE) rs4420638 (? = 0.12 mmol/l per effect allele per decade follow-up, P = 2.0 × 10(-5)), and two TG loci, tribbles pseudokinase 1 (TRIB1) rs2954029 (? = 0.09 mmol/l per effect allele per decade follow-up, P = 5.1 × 10(-4)) and apolipoprotein A-I (APOA1) rs6589564 (? = 0.31 mmol/l per effect allele per decade follow-up, P = 1.4 × 10(-8)), remained significantly associated with longitudinal changes for the respective traits after correction for multiple testing. An additional 12 loci were nominally associated with TC or TG changes. In replication analyses, the APOE rs4420638, TRIB1 rs2954029, and APOA1 rs6589564 associations were confirmed (P ? 0.001). In summary, trait-specific GRSs are robustly associated with 10-yr changes in lipid levels and three individual SNPs were strongly associated with 10-yr changes in lipid levels. PMID:24922540

Varga, Tibor V; Sonestedt, Emily; Shungin, Dmitry; Koivula, Robert W; Hallmans, Göran; Escher, Stefan A; Barroso, Inês; Nilsson, Peter; Melander, Olle; Orho-Melander, Marju; Renström, Frida; Franks, Paul W



Genetic Determinants of Long-Term Changes in Blood Lipid Concentrations: 10-Year Follow-Up of the GLACIER Study  

PubMed Central

Recent genome-wide meta-analyses identified 157 loci associated with cross-sectional lipid traits. Here we tested whether these loci associate (singly and in trait-specific genetic risk scores [GRS]) with longitudinal changes in total cholesterol (TC) and triglyceride (TG) levels in a population-based prospective cohort from Northern Sweden (the GLACIER Study). We sought replication in a southern Swedish cohort (the MDC Study; N?=?2,943). GLACIER Study participants (N?=?6,064) were genotyped with the MetaboChip array. Up to 3,495 participants had 10-yr follow-up data available in the GLACIER Study. The TC- and TG-specific GRSs were strongly associated with change in lipid levels (??=?0.02 mmol/l per effect allele per decade follow-up, P?=?2.0×10?11 for TC; ??=?0.02 mmol/l per effect allele per decade follow-up, P?=?5.0×10?5 for TG). In individual SNP analysis, one TC locus, apolipoprotein E (APOE) rs4420638 (??=?0.12 mmol/l per effect allele per decade follow-up, P?=?2.0×10?5), and two TG loci, tribbles pseudokinase 1 (TRIB1) rs2954029 (??=?0.09 mmol/l per effect allele per decade follow-up, P?=?5.1×10?4) and apolipoprotein A-I (APOA1) rs6589564 (??=?0.31 mmol/l per effect allele per decade follow-up, P?=?1.4×10?8), remained significantly associated with longitudinal changes for the respective traits after correction for multiple testing. An additional 12 loci were nominally associated with TC or TG changes. In replication analyses, the APOE rs4420638, TRIB1 rs2954029, and APOA1 rs6589564 associations were confirmed (P?0.001). In summary, trait-specific GRSs are robustly associated with 10-yr changes in lipid levels and three individual SNPs were strongly associated with 10-yr changes in lipid levels.

Varga, Tibor V.; Sonestedt, Emily; Shungin, Dmitry; Koivula, Robert W.; Hallmans, Goran; Escher, Stefan A.; Barroso, Ines; Nilsson, Peter; Melander, Olle; Orho-Melander, Marju; Renstrom, Frida; Franks, Paul W.



Aging and low back pain among exercise participants: a follow-up study with psychological adaptation factors.  


This study is a follow-up to a study previously published in this journal that reported the moderating function of exercise exertion amid the relationship between age and low back pain (LBP) among consistent exercise participants. The current study analyzed factors of psychological adaptation as potential mediators within the age--LBP relationship. Measures of psychological adaptation included psychological vulnerability, avoidant coping, resilient coping, and perceived resilience. The sample reported slightly moderate psychological vulnerability; a moderate extent of avoidant coping and resilient coping; and high resilience. Age inversely correlated with psychological vulnerability and avoidance coping. LBP correlated inversely with avoidant coping. Avoidant coping positively mediated (enhanced) age's effect on LBP. Results from this follow-up analysis highlight the importance of understanding and testing psychological factors in models with age and a physical health outcome. PMID:20108828

Wilks, Scott E; Kadivar, Zahra; Guillory, Stephen A; Isaza, Jorge



Early Risk Factors for Depressive Symptoms among Korean Adolescents: A 6-to-8 Year Follow-up Study  

PubMed Central

Depression during adolescence is critical to the individual's own development. Hence, identifying individuals with high-risk depression at an early stage is necessary. This study aimed to identify childhood emotional and behavioral risk factors related to depressive symptoms in Korean adolescents through a longitudinal study. The first survey took place from 1998 to 2000, and a follow-up assessment conducted in 2006, as the original participants reached 13-15 yr of age. The first assessment used the Korean version of Child Behavior Checklist and a general questionnaire on family structure, parental education, and economic status to evaluate the participants. The follow-up assessment administered the Korean Children's Depression Inventory. Multiple regression analysis revealed that childhood attention problems predicted depressive symptoms during adolescence for both boys and girls. For boys, family structure also predicted adolescent depressive symptoms. This study suggests that adolescents with attention problems during childhood are more likely to experience depressive symptoms.

Shin, Kyoung Min; Shin, Yun Mi; Park, Kyung Soon



A Follow-up Study on U.S.-Trained Iranian Faculty Members: Satisfactions and Dissatisfactions  

ERIC Educational Resources Information Center

Iran was one of the major contributors to the international student population in the United States. For some years, the number of Iranian students studied in America mounted such that there were more Iranians studying at colleges and universities in the United States than from any other foreign country. This study examined the satisfaction of…

Arasteh, Hamidreza



Changes in T-lymphocyte distribution associated with ingestion of aldicarb-contaminated drinking water: a follow-up study.  


The carbamate pesticide, aldicarb, is the most commonly found man-made groundwater contaminant in Wisconsin. A 1985 study linked ingestion of aldicarb-contaminated drinking water with altered T-cell distributions, specifically an increase in the mean number of CD8+ (T8) T cells. To further evaluate this finding, a follow-up study was done in 1987. Of the 50 Portage County, Wisconsin, women who participated in the first study, 45 participated in the follow-up: 18 formerly exposed and 27 formerly unexposed. In our follow-up study, only 5 women were found to be currently exposed to aldicarb. This group of 5 women, compared to 39 unexposed women who had peripheral blood specimens taken, had an increased percentage of lymphocytes and an increased number of CD2+ T cells, due to an increased number of total CD8+ T cells. Although the number of exposed persons was small, the increases in percentage lymphocytes and absolute numbers of CD2+ and CD8+ T cells were consistent with a dose-response relationship. No identified drinking water contaminant other than aldicarb could explain these findings. These results support earlier evidence linking aldicarb exposure and lymphocyte distribution changes. Although adverse clinical effects have not been documented, the widespread use of this chemical and consequent potential for widespread exposure indicate a clear need for further research on this issue. PMID:2137083

Mirkin, I R; Anderson, H A; Hanrahan, L; Hong, R; Golubjatnikov, R; Belluck, D



Remitting seronegative symmetrical synovitis with pitting oedema (RS3PE) syndrome: a prospective follow up and magnetic resonance imaging study  

Microsoft Academic Search

OBJECTIVETo determine the clinical characteristics of patients with “pure” remitting seronegative symmetrical synovitis with pitting oedema (RS3PE) syndrome, and to investigate its relation with polymyalgia rheumatica (PMR). Magnetic resonance imaging (MRI) was used to describe the anatomical structures affected by inflammation in pure RS3PE syndrome.METHODSA prospective follow up study of 23 consecutive patients with pure RS3PE syndrome and 177 consecutive

Fabrizio Cantini; Carlo Salvarani; Ignazio Olivieri; Libero Barozzi; Luigi Macchioni; Laura Niccoli; Angela Padula; Pietro Pavlica; Luigi Boiardi



Interspinous Process Decompression With the X-STOP Device for Lumbar Spinal Stenosis A 4Year Follow-Up Study  

Microsoft Academic Search

X-STOP is the first interspinous process decompres- sion device that was shown to be superior to nonoperative therapy in patients with neurogenic intermittent claudication secondary to spinal stenosis in the multicenter randomized study at 1 and 2 years. We present 4-year follow-up data on the X-STOP patients. Patient records were screened to identify potentially eligible subjects who underwent X-STOP implanta-

Dimitriy G. Kondrashov; Matthew Hannibal; Ken Y. Hsu; James F. Zucherman


Depression and Suicidal Ideation After Predictive Testing for Huntington's Disease: A Two-Year Follow-up Study  

Microsoft Academic Search

The present study reports a two-year follow-up of psychological effects of predictive testing for Huntington's disease. Questionnaires assessing depression, general health, well-being, self injurious behavior, life satisfaction, and lifestyle were completed by 35 carriers and 58 non-carriers before the predictive test, and 2, 6, 12, and 24 months afterwards. Both carriers and non-carriers showed high suicidal ideation before the predictive

Maria U. Larsson; Mary A. Luszcz; Tarja-Brita Robins Wahlin



Risk of autism spectrum disorders in children born after assisted conception: a population-based follow-up study  

Microsoft Academic Search

ObjectivesTo assess the risk of autism spectrum disorders (ASD) in children born after assisted conception compared with children born after natural conception.DesignPopulation-based follow-up study.SettingAll children born alive in Denmark 1995–2003.Participants588 967 children born in Denmark from January 1995 to December 2003. Assisted conception was defined as in vitro fertilisation (IVF) with or without intracytoplasmic sperm injection and ovulation induction (OI)

D. Hvidtjorn; J. Grove; D. Schendel; L. A. Schieve; C. Svaerke; E. Ernst; P. Thorsen



A Follow-Up Study of Sex Stereotyping in Child-Selected Play Activities of Preschool Children.  

ERIC Educational Resources Information Center

A follow-up study was conducted to determine if changes would occur in the sex stereotyping of child- selected play activities over a 6-month period. Subjects were fifty 3-, 4-, and 5-year-old children enrolled in nursery school programs at a midwestern university during the 1979-80 school year. For one 6-week period in the fall and one in the…

Williams, R. Ann; Beeson, Betty Spillers


Secondary malignancies after treatment for indolent non-Hodgkin's lymphoma: a 16-year follow-up study  

Microsoft Academic Search

Background Relatively little information is available on the incidence of secondary cancer in non-Hodgkin's lymphoma. The aim of this long-term follow-up study was to determine the incidence, the time free of second tumors, and risk factors for developing secondary cancer in a homogeneous group of patients with non-Hodgkin's lymphoma. Design and Methods We evaluated a total of 563 patients with

Stefano Sacchi; Luigi Marcheselli; Alessia Bari; Raffaella Marcheselli; Samantha Pozzi; Stefano Luminari; Marco Lombardo; Gabriele Buda; Antonio Lazzaro; Paolo G. Gobbi; Caterina Stelitano; Fortunato Morabito; Giovanni Quarta; Maura Brugiatelli; Orsola Ciarcia; Caterina Mammi



Homeopathic treatment of patients with chronic sinusitis: A prospective observational study with 8 years follow-up  

Microsoft Academic Search

BACKGROUND: An evaluation of homeopathic treatment and the outcomes in patients suffering from sinusitis for ?12 weeks in a usual care situation. METHODS: Subgroup analysis including all patients with chronic sinusitis (ICD-9: 473.9; ?12 weeks duration) of a large prospective multicentre observational study population. Consecutive patients presenting for homeopathic treatment were followed-up for 2 years, and complaint severity, health-related quality

Claudia M Witt; Rainer Lüdtke; Stefan N Willich



Mortality After Exposure to Polychlorinated Biphenyls and Polychlorinated Dibenzofurans: A 40Year Follow-up Study of Yusho Patients  

Microsoft Academic Search

A 40-year follow-up study was conducted to examine mortality among 1,664 patients in Japan suffering from ''Yusho,'' a disease caused by ingestion of rice oil contaminated with polychlorinated biphenyls and polychlorinated dibenzofurans. To evaluate the effects of exposure on mortality, the authors calculated standardized mortality ratios. National mortality rates for major causes of death were used as reference points. A

Daisuke Onozuka; Takesumi Yoshimura; Satoshi Kaneko; Masutaka Furue


Risk factors for myocardial infarction and death in newly detected NIDDM: the Diabetes Intervention Study, 11-year follow-up  

Microsoft Academic Search

Summary   The Diabetes Intervention Study (DIS) is a prospective population-based multicentre trial of newly detected cases of non-insulin-dependent\\u000a diabetes mellitus (NIDDM). This report analyses the risk factors for subsequent coronary heart disease and all-cause death\\u000a during the 11-year follow-up. The prognostic significance of the categories of the NIDDM Policy Group was validated with respect\\u000a to the incidence of coronary heart

M. Hanefeld; S. Fischer; U. Julius; J. Schulze; U. Schwanebeck; H. Schmechel; H. J. Ziegelasch; J. Lindner



Comparison of early and 1-year follow-up results of conventional hemorrhoidectomy and hemorrhoid artery ligation: a randomized study  

Microsoft Academic Search

Background and aimsDoppler-guided hemorrhoid artery ligation is a new approach for treating hemorrhoids. Early and 1-year follow-up results of the procedure are presented and compared with those of closed scissors hemorrhoidectomy in a prospective randomized study.Patients and methodsSixty consecutively recruited patients were randomized into two groups: group A ( n=30) was treated with standardized closed scissors hemorrhoidectomy and group B

Attila Bursics; Krisztina Morvay; Péter Kupcsulik; Lajos Flautner



Clinical results of meniscus repair with the meniscus arrow: a 4- to 8-year follow-up study  

Microsoft Academic Search

The short-term clinical results of meniscus repair with the meniscus arrow were promising. Unfavorable outcomes were reported\\u000a in two studies, with longer follow-up, raising concerns about the efficacy of this device. We retrospectively reviewed 62\\u000a patients (mean age 23.7 years; range 14–37 years) that underwent all-inside meniscus repair, using the meniscus arrow. Seventeen\\u000a patients had an isolated meniscus tear (ACL intact group)

Nikolaos Koukoulias; Stergios Papastergiou; Konstantinos Kazakos; Georgios Poulios; Konstantinos Parisis



A Follow-Up Study of Psychiatric Consultations in the General Hospital: What Happens to Patients after Discharge?  

Microsoft Academic Search

Background: An appropriate follow-up is considered essential in the consultation-liaison psychiatry setting, but it is often neglected. This study evaluated the effectiveness of the psychiatric consultation process in the general hospital, by investigating what occurred to patients 3–5 months after discharge. Methods: We used a three-part questionnaire: (1) the results of the consultation process; (2) a telephone interview with patients,

M. Rigatelli; L. Casolari; I. Massari; S. Ferrari



Suicidal thoughts and attempts among adolescents: a longitudinal 8-year follow-up study  

Microsoft Academic Search

Background: To study the prevalence of and factors associated with suicidal behaviour among 580 adolescents. Methods: An 8-year longitudinal study included questions about suicidal attempts and thoughts at age 16. Children were evaluated with parent and teacher Rutter scales and self-reported Child Depression Inventory at age 8. At age 16, parents filled in the Child Behaviour Check List and adolescents

Andre Sourander; Leila Helstelä; Antti Haavisto; Lasse Bergroth



Families' Goals, School Involvement, and Children's Academic Achievement: A Follow-Up Study Thirteen Years Later  

ERIC Educational Resources Information Center

A study conducted from 1996-2000 focused on the academic development of children within a statewide educational reform effort, including changing the organizational structure of the early years of schooling into nongraded primary programs (formerly age-based classrooms for kindergarteners through third grade). The multisite study involved children…

Kyle, Diane W.



Follow-Up Study of Department of Education Administration Student Output from 1975 to 1979.  

ERIC Educational Resources Information Center

This study is an evaluation of the educational administration department at West Virginia University. A questionnaire used in a 1975 study was revised and sent to the same departmental graduates and also to their employers. Specific indicators of graduate education quality and relevance were used as was an analysis of the content and instruction…

Andes, John; Martin, James A.


Prognostic factors in major depression: A long-term follow-up study of 323 patients  

Microsoft Academic Search

Background: Optimal long-term treatment of major depression should assess the background factors affecting remission and recurrent episodes. The duration and number of previous depressive episodes has been shown to be important for recurrence. This long-term prospective study of patients with major depression assessed the prognostic effect of variables related to childhood, social life and occupation. Methods: The study examined 323

Trond Riise; Anders Lund



Educational Goal Attainment: A One-Year Follow-Up Study of Nonreturning JCCC Students.  

ERIC Educational Resources Information Center

Each year since 1989, Johnson County Community College (JCCC) (Kansas) has conducted studies on student leavers-- students who have left the community college without graduating, who transferred to other institutions, or who have gained skills through career programs. The most recent study was conducted through mailings to students, of which 699…

Conklin, Karen A.


Baccalaureate and Beyond Longitudinal Study: 1993/97 Second Follow-up Methodology Report. Technical Report.  

ERIC Educational Resources Information Center

The Baccalaureate and Beyond Longitudinal Study (B&B) tracks the experiences of a cohort of college graduates who received their baccalaureate degrees during the 1992-93 academic year and who were first interviewed as part of the National Postsecondary Student Aid Study. The experiences of this group in the areas of academic enrollment, degree…

Greene, Patricia; Myers, Sharon; Veldman, Cynthia; Pedlow, Stephen


The Bounce Back Retention Program: One-Year Follow-Up Study  

ERIC Educational Resources Information Center

This study provides results regarding the effectiveness of the Bounce Back Retention Program (BBRP), a semester-long voluntary course for students on academic probation (AP). This is the first phase of a longitudinal study of spring 2007 freshmen at San Diego State University (SDSU). Results were analyzed for three samples: 1) "AP BBRP-Credit"…

Hanger, Maria Andujo; Goldenson, Julie; Weinberg, Marsha; Schmitz-Sciborski, Amy; Monzon, Reynaldo



Follow-Up Study of the 1997 Pine Valley, Michigan High School Graduating Class.  

ERIC Educational Resources Information Center

This report describes the background, nature of, and results from a survey of the 1997 Pine Valley High School (Michigan) graduating class. Pine Valley is a name used for purposes of the report. The questionnaire, administered in June 1997, was designed to: (1) identify the curriculum areas students wished they had studied or studied in greater…

Pasch, Marvin; Kacanek, Paul; Huyvaert, Sara


Adjustment to Spinal Cord Injury: A Comprehensive Follow-Up Study.  

ERIC Educational Resources Information Center

This document reports a comprehensive followup study to describe postservice life status of former vocational rehabilitation clients and to develop an empirical index of postservice adjustment to spinal cord injury. Significant findings, conclusions, and implications are found at the beginning. The introduction section summarizes followup studies

Cook, Daniel; And Others


Adjustment to University and Academic Performance: Brief Report of a Follow-Up Study  

ERIC Educational Resources Information Center

This study presents data that extend an earlier analysis of predictors of academic performance from one to three years. None of the adjustment and other psychosocial variables (help-seeking, academic motivation, self-esteem, perceived stress and perceived academic overload) could predict success at university at the end of three years of study.…

Petersen, Il-haam; Louw, Johann; Dumont, Kitty; Malope, Nomxolisi



Adjustment to university and academic performance: brief report of a follow?up study  

Microsoft Academic Search

This study presents data that extend an earlier analysis of predictors of academic performance from one to three years. None of the adjustment and other psychosocial variables (help?seeking, academic motivation, self?esteem, perceived stress and perceived academic overload) could predict success at university at the end of three years of study. The only significant predictor was academic performance at the end

Johann Louw; Kitty Dumont; Nomxolisi Malope



Mobile phone text messaging and Telephone follow-up in type 2 diabetic patients for 3 months: a comparative study  

PubMed Central

Background To investigate and to compare the effectiveness of a nurse short message service (SMS) by cellular phone and telephone follow-up by nurse on Glycosylated hemoglobin (HbA1c) levels in people with type 2 diabetes. Methods Semi experimental study consisted of 77 patients with type 2 diabetes that randomly assigned to two groups: telephone follow-up (n?=?39) and short message service (n?=?38). Telephone interventions were applied by researcher for 3 months. SMS group that received message daily for 12 weeks. Data gathering instrument include data sheet to record HbA1c and questionnaire that consisted of demographic characteristics. Data gathering was performed at two points: initial the study and after 12 weeks. Data analyzed using descriptive and inferential statistics methods with SPSS version 11.5. Results Demographic variables were compared and all of them were homogenous. Results of this study showed that both interventions had significant mean changes in HbA1c; for the telephone group (p?=?0.001), with a mean change of ?0.93% and for the SMS group (p?=?0.001), with a mean change of ?1.01%. Conclusion Finding of this research showed that intervention using SMS via cellular phone and nurse-led-telephone follow up improved HbA1c for three months in type 2 diabetic patients and it can consider as alternative methods for diabetes control.



The ten-year survival of the Birmingham hip resurfacing: an independent series.  


Recent events have highlighted the importance of implant design for survival and wear-related complications following metal-on-metal hip resurfacing arthroplasty. The mid-term survival of the most widely used implant, the Birmingham Hip Resurfacing (BHR), has been described by its designers. The aim of this study was to report the ten-year survival and patient-reported functional outcome of the BHR from an independent centre. In this cohort of 554 patients (646 BHRs) with a mean age of 51.9 years (16.5 to 81.5) followed for a mean of eight years (1 to 12), the survival and patient-reported functional outcome depended on gender and the size of the implant. In female hips (n = 267) the ten-year survival was 74% (95% confidence interval (CI) 83 to 91), the ten-year revision rate for pseudotumour was 7%, the mean Oxford hip score (OHS) was 43 (SD 8) and the mean UCLA activity score was 6.4 (SD 2). In male hips (n = 379) the ten-year survival was 95% (95% CI 92.0 to 97.4), the ten-year revision rate for pseudotumour was 1.7%, the mean OHS was 45 (SD 6) and the mean UCLA score was 7.6 (SD 2). In the most demanding subgroup, comprising male patients aged < 50 years treated for primary osteoarthritis, the survival was 99% (95% CI 97 to 100). This study supports the ongoing use of resurfacing in young active men, who are a subgroup of patients who tend to have problems with conventional THR. In contrast, the results in women have been poor and we do not recommend metal-on-metal resurfacing in women. Continuous follow-up is recommended because of the increasing incidence of pseudotumour with the passage of time. PMID:22933488

Murray, D W; Grammatopoulos, G; Pandit, H; Gundle, R; Gill, H S; McLardy-Smith, P



Follow-up Studies of the Appalachian Education Satellite Project Experimental Phase.  

National Technical Information Service (NTIS)

This report presents the results of followup studies concerning participants' attitudes and reactions to two courses delivered during the experimental phase of the Appalachian Education Satellite Project (AESP). Graduate level teacher training was the obj...

J. L. Fitzpatrick D. M. Mertens



Treatment Compliance of Adolescents after Attempted Suicide: A 2-Year Follow-Up Study  

ERIC Educational Resources Information Center

The study investigates compliance with mental health treatments among suicidal adolescents. Results show that child psychopathology and parental attitudes toward treatment plays an important part in increasing compliance with mental health treatment for adolescent suicide attempters.

Burns, Craig D.; Cortell, Ranon; Wagner, Barry M.



Insulin resistance, adiponectin and adverse outcomes following elective cardiac surgery: a prospective follow-up study  

Microsoft Academic Search

BACKGROUND: Insulin resistance and adiponectin are markers of cardio-metabolic disease and associated with adverse cardiovascular outcomes. The present study examined whether preoperative insulin resistance or adiponectin were associated with short- and long-term adverse outcomes in non-diabetic patients undergoing elective cardiac surgery. METHODS: In a prospective study, we assessed insulin resistance and adiponectin levels from preoperative fasting blood samples in 836

Martin M Mikkelsen; Troels K Hansen; Jakob Gjedsted; Niels H Andersen; Thomas D Christensen; Vibeke E Hjortdal; Søren P Johnsen



A 12-year follow-up study of treated obese children in Japan  

Microsoft Academic Search

Objective: To assess tracking for body weight from childhood to adulthood in obese Japanese children who were treated for obesity, investigate the relation between the changes in body weight status and morbidity, and identify correlates of the changes in body weight status.Study Design: Twelve-year retrospective cohort study.Subjects: A sample of 276 subjects (age 23.9±4.1, 176 males and 100 females) who

K Togashi; H Masuda; T Rankinen; S Tanaka; C Bouchard; H Kamiya



Follow-up study of pulmonary artery configuration in hypoplastic left heart syndrome  

Microsoft Academic Search

Objective. Pulmonary artery (PA) distortion significantly compromises the outcome of the staged approach to the Fontan operation in\\u000a patients with hypoplastic left heart syndrome (HLHS). This retrospective study was designed to investigate the influence of\\u000a the initial operation on postoperative PA anatomy.\\u000a \\u000a \\u000a Methods. Forty-nine patients with HLHS and its variant were enrolled in this study. As an initial palliation, the

Toshihide Nakano; Koji Fukae; Hiromichi Sonoda; Tsuyoshi Tachibana; Masaki Kajimoto; Yusuke Ando; Hideaki Kado



Gender differences in outcomes of acute mania: a 12-month follow-up study  

Microsoft Academic Search

This study aimed to assess short-term (12 weeks) and long-term (12 months) gender differences in the outcomes of patients\\u000a experiencing an episode of mania in the course of bipolar disorder. European Mania in Bipolar Longitudinal Evaluation of Medication\\u000a was a 2-year, prospective, observational study of the outcomes of patients with a manic or mixed episode conducted in 14 European\\u000a countries. Data were

Laia Miquel; Judith Usall; Catherine Reed; Jordan Bertsch; Eduard Vieta; Ana González-Pinto; Jules Angst; Willem Nolen; Inge van Rossum; Josep Maria Haro




EPA Science Inventory

The purpose of this SOP is to define the coding strategy for the Follow Up Questionnaire. This questionnaire was developed for use in the Arizona NHEXAS project and the Border study. Household and individual follow-up data were combined in a single Follow-up Questionnaire data f...


Psychotropic drug use among people with dementia - a six-month follow-up study  

PubMed Central

Background Psychotropic drugs are widely used among old people with dementia but few studies have described long-term treatment in this group of patients. The purpose of this study was to explore the long-term use of psychotropic drugs in old people with dementia. Methods Data on psychotropic drug use, functioning in the activities of daily living (ADL), cognitive function and behavioral and psychological symptoms were collected at baseline and six months later, using the Multi-Dimensional Dementia Assessment Scale (MDDAS). The data were collected in 2005–2006. Detailed data about the prescribing of psychotropic drugs were collected from prescription records. This study was conducted in 40 specialized care units in northern Sweden, with a study population of 278 people with dementia. Results At the start of the study, 229 of the participants (82%) were prescribed at least one psychotropic drug; 150 (54%) used antidepressants, 43 (16%) used anxiolytics, 107 (38%) used hypnotics and sedatives, and 111 (40%) used antipsychotics. Among the baseline users of antidepressants, anxiolytics, hypnotics and sedatives and antipsychotics, 67%, 44%, 57% and 57% respectively, still used the same dose of the same psychotropic drug after six months. Associations were found between behavioral and psychological symptoms and different psychotropic drugs. Conclusion Psychotropic drug use was high among people with dementia living in specialized care units and in many cases the drugs were used for extended periods. It is very important to monitor the effects and adverse effects of the prescribed drug in this frail group of people.



Neurological follow-up of 281 children born in breech presentation: a controlled study.  

PubMed Central

A study was conducted of all children delivered in breech presentation from 1969 to 1977 in the university's department of obstetrics. One-fifth of the deliveries were by caesarean section. Perinatal mortality was high (13.2%) but was due almost exclusively to causes other than the birth itself. The 256 surviving children and their matched controls were neurologically examined at 18 months or at ages varying between 3 and 10 years. The attrition rate was 5.7%, but in most cases data on development were available. Significant differences between the study and control groups existed for only minor neurological dysfunctions. It is concluded that the main danger of breech presentation is in the associated complications of pregnancy and that there is no reason to advocate a higher frequency of abdominal delivery than the 20% found in this study.

Faber-Nijholt, R; Huisjes, H J; Touwen, B C; Fidler, V J



Genome-wide linkage and follow-up association study of postpartum mood symptoms  

PubMed Central

Objective Family studies have suggested that postpartum mood symptoms might have a partly genetic etiology. The authors used a genome-wide linkage analysis to search for chromosomal regions that harbor genetic variants conferring susceptibility for such symptoms. The authors then fine-mapped their best linkage regions, assessing single nucleotide polymorphisms (SNPs) for genetic association with postpartum symptoms. Method Subjects were ascertained from two studies: the NIMH Genetics Initiative Bipolar Disorder project and the Genetics of Recurrent Early-Onset Depression. Subjects included women with a history of pregnancy, any mood disorder, and information about postpartum symptoms. In the linkage study, 1,210 women met criteria (23% with postpartum symptoms), and 417 microsatellite markers were analyzed in multipoint allele sharing analyses. For the association study, 759 women met criteria (25% with postpartum symptoms), and 16,916 SNPs in the regions of the best linkage peaks were assessed for association with postpartum symptoms. Results The maximum linkage peak for postpartum symptoms occurred on chromosome 1q21.3-q32.1, with a chromosome-wide significant likelihood ratio Z score (ZLR) of 2.93 (permutation p=0.02). This was a significant increase over the baseline ZLR of 0.32 observed at this locus among all women with a mood disorder (permutation p=0.004). Suggestive linkage was also found on 9p24.3-p22.3 (ZLR=2.91). In the fine-mapping study, the strongest implicated gene was HMCN1 (nominal p=0.00017), containing four estrogen receptor binding sites, although this was not region-wide significant. Conclusions This is the first study to examine the genetic etiology of postpartum mood symptoms using genome-wide data. The results suggest that genetic variations on chromosomes 1q21.3-q32.1 and 9p24.3-p22.3 may increase susceptibility to postpartum mood symptoms.

Mahon, PB; Payne, JL; MacKinnon, DF; Mondimore, FM; Goes, FS; Schweizer, B; Jancic, D; Coryell, WH; Holmans, PA; Shi, J; Knowles, JA; Scheftner, WA; Weissman, MM; Levinson, DF; DePaulo, JR; Zandi, PP; Potash, JB



Relations between Achievement Goal Orientations and Math Achievement in Primary Grades: A Follow-Up Study  

ERIC Educational Resources Information Center

The aim of the present study was to investigate children's achievement goal orientations and their relations to math achievement in the primary grades. The sample consisted of 179 children who were in the 2nd and 3rd grades during the first measurement and in the 3rd and 4th grades during the second measurement. Children's self-ratings were…

Magi, Katrin; Lerkkanen, Marja-Kristiina; Poikkeus, Anna-Maija; Rasku-Puttonen, Helena; Kikas, Eve



The Longitudinal Assessment Study (LAS): Eighteen Year Follow-Up. Final Report.  

ERIC Educational Resources Information Center

Premised on the view that students with more years of Montessori education (MEY) would possess to a higher degree those qualities emphasized in the Montessori environment and that Montessori students would be as successful as students more traditionally educated, this report presents the final assessment for the Longitudinal Assessment Study,…

Glenn, Christopher M.


Emotional Psychopathology and Increased Adiposity: Follow-Up Study in Adolescents  

ERIC Educational Resources Information Center

Based on data from a three-year longitudinal study, we assess the effect, according to gender, of emotional psychopathology in preadolescence on anthropometric and body composition parameters in adolescence (N = 229). Psychopathology was assessed using the "Screen for Childhood Anxiety and Related Emotional Disorders, the Children's Depression…

Aparicio, Estefania; Canals, Josefa; Voltas, Nuria; Hernandez-Martinez, Carmen; Arija, Victoria



Assertive Community Treatment (ACT) in Singapore: A 1-year Follow-up Study  

Microsoft Academic Search

Introduction: Assertive Community Treatment (ACT) provides community-based treatment to patients with severe and persistent psychiatric illnesses, so that they may continue to live and function in the community as they receive psychiatric care. This study aimed to examine the effects of ACT on the outcome of patients over a 1-year period in an Asian population. Materials and Methods: This naturalistic

Johnson Fam; Cheng Lee; Boon-Leng Lim; Kiang-Kim Lee



Long-term follow-up study of West syndrome: differences of outcome among symptomatic etiologies  

Microsoft Academic Search

Objectives To evaluate the outcome of West syndrome and to elucidate the differences in the outcome related to the timing of brain injury.Study design Medical records of 60 patients who were followed regularly for more than seven years were reviewed. The following clinical features were assessed: onset, seizure evolution, electroencephalography and intelligence. Those variables were compared among five groups: cryptogenic,

Shin-Ichiro Hamano; Manabu Tanaka; Mika Mochizuki; Nobuyoshi Sugiyama; Yoshikatsu Eto



Follow-Up Study to Investigate Blood Lead Levels in Children in Galena, Kansas.  

National Technical Information Service (NTIS)

A prevalence study of blood and environmental lead levels was conducted in Galena, Kansas, a heavy metal mining Superfund site. The area is part of an abandoned lead/zinc mining and smelting region often called the Tri-State Mining District (Kansas, Misso...



Follow-Up Study of Rural Schools Implementing CSR Programs in the Southwest. Research Report.  

ERIC Educational Resources Information Center

Case studies of five small and isolated rural schools in the Southwest focused on their ability to fully implement Comprehensive School Reform Demonstration (CSR) programs over the 3-year period of their federal grants. Data were gathered via interviews with school personnel, classroom observations, document reviews, and telephone interviews with…

Carlson, Robert V.


Recovery of Functional Impairment after Acute Illness and Mortality: One-Year Follow-Up Study  

Microsoft Academic Search

Background: Functional status in older people is a dynamic situation, which makes it necessary to evaluate functional capacity at different times to determinate their prognostic value. Objective: To examine the association between functional status (baseline and change after acute illness) and mortality and functional changes at 1 year. Methods: Hospital-based prospective longitudinal cohort study of all patients over 65 years

Juan J. Baztán; César P. Gálvez; Alberto Socorro



Problems and Perspectives of Beginning Teachers: A Follow-Up Study.  

ERIC Educational Resources Information Center

Beginning teachers were studied from the completion of student teaching through the first nine weeks of instruction as professional teachers. Data was collected at the end of student teaching, the end of school orientation, and at the end of the third and ninth weeks of teaching. In addition, they reported their concerns and problems and the means…

Felder, B. Dell; And Others


Polybrominated diphenyl ether exposure to electronics recycling workers – a follow up study  

Microsoft Academic Search

Workers at an electronics recycling plant have previously been shown to have elevated serum levels of polybrominated diphenyl ethers (PBDEs) compared to referents without occupational PBDE exposure. Subsequent structural changes and industrial hygiene measures at the plant were applied to improve the work environment. The present study aims to assess the impact of these work environment changes on the occupational

Kaj Thuresson; Åke Bergman; Klaus Rothenbacher; Thomas Herrmann; Sverker Sjölin; Lars Hagmar; Olaf Päpke; Kristina Jakobsson



Substance use and abuse among adolescent runaways: A four-year follow-up study  

Microsoft Academic Search

Using data from the National Longitudinal Study Youth Survey (NLSY), runaway status in early adolescence (ages 14–15) was associated with subsequent (four years later) substance abuse, alcohol problems, and school dropout status. Three runaway categories were formed—never runaway, runaway once, and runaway two or more times. Overall, the repeat runaways reported engaging in higher levels of substance use and abuse

Michael Windle



Substance Use and Abuse among Adolescent Runaways: A Four-Year Follow-Up Study.  

ERIC Educational Resources Information Center

Using National Longitudinal Study Youth Survey data for 1,241 males and 1,143 females, runaway status in early adolescence--ages 14-15 years--was associated with subsequent--4 years later--substance abuse, alcohol problems, and school-dropout status. Gender and number of runaway episodes were considered. Repeat-runaways reported higher substance…

Windle, Michael



The Breast Cancer Detection Demonstration Project (BCDDP) Follow-up Study

Study subjects were participants in the Breast Cancer Detection Demonstration Project (BCDDP), a breast cancer screening program conducted between 1973 and 1980. Sponsored by the American Cancer Society and the NCI, the BCDDP provided up to five annual breast examinations to 283,222 women at 29 screening centers in 27 cities throughout the United States.


Public University Baccalaureate Follow-Up Study. May 2011 [Revised Feb 2012  

ERIC Educational Resources Information Center

This report provides the results of analysis of more than 40,000 students who received baccalaureate degrees from the public baccalaureate institutions in Washington during the 2005-06 and 2006-07 academic years. The purpose of this study was to follow students after graduation to determine the extent to which degree recipients were able to secure…

Washington Higher Education Coordinating Board, 2012



Lasting Benefits of Cooperative Editing for Remedial Freshman Composition Students: A Follow-Up Study.  

ERIC Educational Resources Information Center

Describes a study that investigated whether cooperative editing had lasting benefits for remedial freshman composition students. Reports that students who had been taught the application of standard written grammar made significantly higher mean grades in freshman composition than students who had been taught using only textbooks, discussion, and…

Minchew, Sue S.; McGrath, Vincent R.



Cognitive Deficits Associated with Acquired Amusia after Stroke: A Neuropsychological Follow-Up Study  

ERIC Educational Resources Information Center

Recent evidence on amusia suggests that our ability to perceive music might be based on the same neural resources that underlie other higher cognitive functions, such as speech perception and spatial processing. We studied the neural correlates of acquired amusia by performing extensive neuropsychological assessments on 53 stroke patients with a…

Sarkamo, Teppo; Tervaniemi, Mari; Soinila, Seppo; Autti, Taina; Silvennoinen, Heli M.; Laine, Matti; Hietanen, Marja



Pubertal Timing and Substance Use in Middle Adolescence: A 2-Year Follow-Up Study  

ERIC Educational Resources Information Center

Earlier research has associated early puberty with emotional and behavioral symptoms particularly among girls, while among boys, findings have been contradictory as to whether risks are associated with early or late pubertal timing. We studied the association between pubertal timing and substance use behaviors in middle adolescence in a 2-year…

Kaltiala-Heino, Riittakerttu; Koivisto, Anna-Maija; Marttunen, Mauri; Frojd, Sari



Who Leaves and Who Stays in Special Education: A 2-Year Follow-up Study.  

ERIC Educational Resources Information Center

A two-year study assessing the stability of 1,184 elementary special education students found 71 percent stayed in special education with the same classification, 12 percent remained with a different classification, and 17 percent were no longer in special education. The original primary classification was the best predictor of reclassification…

Walker, Deborah K.; And Others



Life Events and Survival in Dementia: A 5Year Follow-Up Study  

Microsoft Academic Search

Objectives: To examine the relationship between life events and survival for people with dementia. To investigate whether this relationship differs from that for people without dementia. To identify which psychiatric and social factors are associated with survival in people with dementia.Method: A prospective cohort study with external controls. One hundred and sixteen people with dementia and 50 fit, elderly controls

Rob Butler; Martin Orrell; Obioha C. Ukoumunne; Paul Bebbington



A Follow-up Study of Students Who Withdrew from Oswego, 1974-75.  

ERIC Educational Resources Information Center

Students who withdrew from the State University of New York at Oswego during academic year 1974-1975 were surveyed to study the differences between them and their classmates who persisted. A sample of 52 students responded to questionnaires inquiring why they had chosen to attend Oswego, why they left early, and what their present educational…

Garber, Herbert


Educational Goal Attainment: A One-Year Follow-up Study of Nonreturning JCCC Students.  

ERIC Educational Resources Information Center

In 1989, Johnson County Community College (JCCC, Kansas) conducted studies of "leavers"--students who had been enrolled at JCCC during a specific period of time and had not graduated, earned a certificate, transferred to another college or university, or left the college with marketable skills developed in one of JCCC's career programs. Results of…

Conklin, Karen A.


A Follow-Up Study of Junior College Hotel and Restaurant Education in Florida.  

ERIC Educational Resources Information Center

This study examines hospitality programs from the enabling legislation in 1961, which provided for an advisory committee to the Hotel and Restaurant Commission on education. Its purpose was to employ a director of the programs and two field representatives or consultants to offer on-the-job assistance to managers and employees in the state's…

Almarode, Richard L.


A Follow-Up Study to Compare Success Rates of Developmental Math Students  

ERIC Educational Resources Information Center

This article presents a study that compared the success rates of students in Arithmetic (MTH 02), Algebra I (MTH 03), and Algebra II (MTH 03) when they were offered at Southwest Virginia Community College (SWCC) for three credits versus five credits. The authors' findings showed no significant differences in the success rates of students who were…

Woodard, Teresa; Burkett, Sexton



Longitudinal assessment of coherence in an adult with fluent aphasia: A follow-up study  

Microsoft Academic Search

Background: It has been suggested that individuals with fluent aphasia demonstrate microlinguistic impairments and relatively preserved macrolinguistic abilities (Glosser & Deser, 1990). However, results of a previous study in which measures of sentence production, intersentential cohesion, and story grammar were assessed longitudinally over a period of 12 months did not support this contention (Coelho, Liles, Duffy, Clarkson, & Elia, 1994).

Carl Coelho; Laura Flewellyn



Follow-Up Study of Fiscal Year 1997 Occupational Program Graduates, 1998.  

ERIC Educational Resources Information Center

This report provides information from graduates of selected occupational programs regarding the effectiveness of their Illinois community college experience. The study surveyed a pool of 2,190 occupational program graduates, which yielded a usable response rate of 58.6%. The majority of graduate respondents (64.5%) came from programs in four…

Illinois Community Coll. Board, Springfield.


Spontaneous abortions among dental assistants, factory workers, painters, and gardening workers: a follow up study.  

PubMed Central

This investigation was conducted to test the hypothesis that exposure of pregnant women to chemicals increases the risk of spontaneous abortion. The chemical risk factors under study to which dental assistants, factory workers, painters, and gardening workers were exposed were nitrous oxide, inorganic mercury, organic solvents, and pesticides. The study was carried out within the Danish county of Funen. It included all dental assistants employed in private or public dentistry. A comparable reference group was made up by employees less exposed to chemicals. Further study groups included all women painters within the county, women factory workers from selected factories, and about 50% of the women gardening workers within the county. Shop assistants and packers formed their control group. Information was obtained through a postal questionnaire study in May 1980 and from hospital records. Only among factory workers and painters was the odds ratio of spontaneous abortion found to be significantly increased. Neither among these women nor among dental assistants and gardening workers, however, was the reported exposure to any single chemical during pregnancy associated with a significantly increased odds ratio of spontaneous abortion.

Heidam, L Z



Motor Development in Children at Risk of Autism: A Follow-Up Study of Infant Siblings  

ERIC Educational Resources Information Center

Recently, evidence of poor or atypical motor skills in autism spectrum disorder has led some to argue that motor impairment is a core feature of the condition. The current study uses a longitudinal prospective design to assess the development of motor skills of 20 children at increased risk of developing autism spectrum disorder, who were…

Leonard, Hayley C.; Bedford, Rachael; Charman, Tony; Elsabbagh, Mayada; Johnson, Mark H.; Hill, Elisabeth L.



Arthroscopic versus mini-open rotator cuff repair: a prospective, randomized study with 24-month follow-up.  


This prospective, randomized study was performed to evaluate the results of mini-open and arthroscopic rotator cuff repair in a comparative case series of patients followed for 24 months. A total of 125 patients were randomized to mini-open (Group I) or arthroscopic (Group II) rotator cuff repair at the time of surgical intervention. The University of California Los Angeles (UCLA) score, the American Shoulder and Elbow Surgeons (ASES) index, and muscle strength were measured to evaluate the clinical results, while magnetic resonance arthrography was used at 24-month follow-up to investigate the postoperative rotator cuff integrity. Fifty-three patients in Group I and 55 patients in Group II were available for evaluation at 24-month follow-up. At 24-month follow-up, the UCLA score, the ASES index, and muscle strength were statistically significantly increased in both groups postoperatively, while no significant difference was detected between the 2 groups. Intact rotator cuffs were investigated in 42 patients in Group I and 35 in Group II, and there was a significant difference in postoperative structural integrity between the two groups (P < 0.05). When analysis was limited to the patients with full-thickness tear, the muscle strength of the shoulder was significantly better in Group II, and the retearing rate was