Sample records for thyroid-associated ophthalmopathy tao

  1. TSH-receptor-expressing fibrocytes and thyroid-associated ophthalmopathy.

    PubMed

    Smith, Terry J

    2015-03-01

    Thyroid-associated ophthalmopathy (TAO) is a vexing and undertreated ocular component of Graves disease in which orbital tissues undergo extensive remodelling. My colleagues and I have introduced the concept that fibrocytes expressing the haematopoietic cell antigen CD34 (CD34(+) fibrocytes), which are precursor cells of bone-marrow-derived monocyte lineage, express the TSH receptor (TSHR). These cells also produce several other proteins whose expression was traditionally thought to be restricted to the thyroid gland. TSHR-expressing fibrocytes in which the receptor is activated by its ligand generate extremely high levels of several inflammatory cytokines. Acting in concert with TSHR, the insulin-like growth factor 1 receptor (IGF-1R) expressed by orbital fibroblasts and fibrocytes seems to be necessary for TSHR-dependent cytokine production, as anti-IGF-1R blocking antibodies attenuate these proinflammatory actions of TSH. Furthermore, circulating fibrocytes are highly abundant in patients with TAO and seem to infiltrate orbital connective tissues, where they might transition to CD34(+) fibroblasts. My research group has postulated that the infiltration of fibrocytes into the orbit, their unique biosynthetic repertoire and their proinflammatory and profibrotic phenotype account for the characteristic properties exhibited by orbital connective tissues that underlie susceptibility to TAO. These insights, which have emerged in the past few years, might be of use in therapeutically targeting pathogenic orbit-infiltrating fibrocytes selectively by utilizing novel biologic agents that interfere with TSHR and IGF-1R signalling. PMID:25560705

  2. Selenium supplementation in thyroid associated ophthalmopathy: an update

    PubMed Central

    Dharmasena, Aruna

    2014-01-01

    The therapeutic effect of selenium (Se) has already been proven in thyroid disease and thyroid associated ophthalmopathy (TAO). In spite of clear scientific proof of its benefits in TAO, there appears to be no clear agreement among the clinicians regarding its optimum dose, duration of the treatment, efficacy and safety to date. In this review, the author summarises the findings of 135 English language articles published on this subject over the past four decades from 1973 to 2013. The regulation and metabolism of thyroid hormones require a steady supply of Se and recent studies have revealed several possible mechanisms by which Se improves the severity of thyroid disease and TAO. These mechanisms include 1) inhibitory effect of HLA-DR molecule expression on thyrocytes; 2) profound reductions of thyroid stimulating hormone (TSH) receptor antibodies (TSHR-Ab) and TPO antibodies (TPO-Ab); 3) prevention of dysregulation of cell-mediated immunity and B cell function; 4) neutralising reactive oxygen species (ROS) and inhibition of redox control processes required for the activation, differentiation and action of lymphocytes, macrophages, neutrophils, natural killer cells involved in both acute and chronic orbital inflammation in TAO; 5) inhibition of expression of pro-inflammatory cytokines and 6) inhibition of prostaglandin and leukotriene synthesis. An increased oxidative stress has been observed in both acute and chronic phases of thyroid disease with raised tissue concentrations of ROS. The benefits of Se supplementation in individuals with TAO appear to be proportionate to the degree of systemic activity of the thyroid disease. The maximal benefit of Se supplementation is therefore seen in the subjects who are hyperthyroid. Restoration of euthyroidism is one of the main goals in the management of TAO and when anti-thyroid drugs are combined with Se, the patients with Graves' disease (GD) and autoimmune thyroiditis (AIT) achieved euthyroidism faster than those treated with anti-thyroid drugs alone. Se status of normal adult humans can vary widely and Se supplementation may confer benefit only if serum Se levels are insufficient. The author recommends that serum Se levels of patients with TAO to be assessed prior to and during Se supplementation at regular intervals to avoid potential iatrogenic chronic Se overdose. PMID:24790886

  3. Selenium supplementation in thyroid associated ophthalmopathy: an update.

    PubMed

    Dharmasena, Aruna

    2014-01-01

    The therapeutic effect of selenium (Se) has already been proven in thyroid disease and thyroid associated ophthalmopathy (TAO). In spite of clear scientific proof of its benefits in TAO, there appears to be no clear agreement among the clinicians regarding its optimum dose, duration of the treatment, efficacy and safety to date. In this review, the author summarises the findings of 135 English language articles published on this subject over the past four decades from 1973 to 2013. The regulation and metabolism of thyroid hormones require a steady supply of Se and recent studies have revealed several possible mechanisms by which Se improves the severity of thyroid disease and TAO. These mechanisms include 1) inhibitory effect of HLA-DR molecule expression on thyrocytes; 2) profound reductions of thyroid stimulating hormone (TSH) receptor antibodies (TSHR-Ab) and TPO antibodies (TPO-Ab); 3) prevention of dysregulation of cell-mediated immunity and B cell function; 4) neutralising reactive oxygen species (ROS) and inhibition of redox control processes required for the activation, differentiation and action of lymphocytes, macrophages, neutrophils, natural killer cells involved in both acute and chronic orbital inflammation in TAO; 5) inhibition of expression of pro-inflammatory cytokines and 6) inhibition of prostaglandin and leukotriene synthesis. An increased oxidative stress has been observed in both acute and chronic phases of thyroid disease with raised tissue concentrations of ROS. The benefits of Se supplementation in individuals with TAO appear to be proportionate to the degree of systemic activity of the thyroid disease. The maximal benefit of Se supplementation is therefore seen in the subjects who are hyperthyroid. Restoration of euthyroidism is one of the main goals in the management of TAO and when anti-thyroid drugs are combined with Se, the patients with Graves' disease (GD) and autoimmune thyroiditis (AIT) achieved euthyroidism faster than those treated with anti-thyroid drugs alone. Se status of normal adult humans can vary widely and Se supplementation may confer benefit only if serum Se levels are insufficient. The author recommends that serum Se levels of patients with TAO to be assessed prior to and during Se supplementation at regular intervals to avoid potential iatrogenic chronic Se overdose. PMID:24790886

  4. Treatment of thyroid associated ophthalmopathy with periocular injections of triamcinolone

    PubMed Central

    Ebner, R; Devoto, M H; Weil, D; Bordaberry, M; Mir, C; Martinez, H; Bonelli, L; Niepomniszcze, H

    2004-01-01

    Aim: To evaluate the efficacy of periocular triamcinolone acetonide for the treatment of thyroid associated ophthalmopathy (TAO), and the presence of ocular or systemic adverse effects. Methods: A multicentre prospective pilot study was performed on patients diagnosed with Graves’ ophthalmopathy less than 6 months before entry to the study. Patients were admitted to the study and were randomised into two groups: treatment and control. The treatment group received four doses of 20 mg of triamcinolone acetate 40 mg/ml in a peribulbar injection to the inferolateral orbital quadrant. Both groups were evaluated by measuring the area of binocular vision without diplopia on a Goldmann perimeter and the size of the extraocular muscles on computed tomography (CT) scans. Ophthalmological and systemic examinations were done to rule out ocular and systemic adverse effects. Follow up was 6 months for both groups. Results: 50 patients were eligible for the study. 41 patients completed the study. There was an increase in the area of binocular vision without diplopia in the treatment group (? initial: mean 231.1 (SD 99.9) and final absolute change, mean 107.1 (SD 129.0)) compared to the control group (? initial: mean 350.7 (SD 86.5) and final absolute change, mean ?4.5 (SD 67.6)). The sizes of the extraocular muscles were reduced in the treatment group (mean (inferior rectus initial values): 1.3 (0.7), final percentage change: ?13.2 (25.7), medial rectus initial values: 1.2 (0.6), final percentage change: ?8.2 (20.7), superior rectus-levator palpebrae initial values: 1.2 (0.6), final percentage change: ?9.5 (29.1), lateral rectus initial values: 1.0 (0.4), final percentage change: ?11.5 (20.6)) compared to the control group (inferior rectus initial values: 0.9 (0.3), final percentage change: ?4.0 (21.5), medial rectus initial values: 0.9 (0.3), final percentage change: 0.6 (22.4), superior rectus-levator palpebrae initial values: 0.9 (0.3), final percentage change: 12.5 (37.5), lateral rectus initial values: 0.9 (0.4), final percentage change: ?0.5 (31.6)). Both measurements (degree of diplopia and muscle thickness) were statistically significant between groups (initial ? final). No systemic or ocular adverse effects were found. Conclusions: Triamcinolone administered as a periocular injection is effective in reducing diplopia and the sizes of extraocular muscles in TAO ophthalmopathy of recent onset. This form of treatment is not associated with systemic or ocular side effects. PMID:15489477

  5. CT features of exophthalmos in Chinese subjects with thyroid-associated ophthalmopathy

    PubMed Central

    Fang, Zhi-Jia; Zhang, Jenny Y.; He, Wei-Min

    2013-01-01

    AIM : To investigate computed tomography (CT) features of exophthalmos in Chinese subjects with thyroid-associated ophthalmopathy (TAO). METHODS A total of 605 eyes of 325 patients with exophthalmos due to TAO were classified as grade I (mild exophthalmos) or II (severe exophthalmos) based on orbital CT imaging. The increased orbital volume features, such as changes from extraocular muscles, orbital fat, or both, were analyzed. RESULTS A total of 605 eyes were analyzed, among them 62.98% presented grade I exophthalmos, while 36.02% showed grade II exophthalmos. In grade I, 56.69% showed orbital fat change, and in grade II, 89.29% exhibited extraocular muscle enlargement. CONCLUSION Orbital fat and extraocular muscle enlargement are likely to be observed on CTs of subjects with mild and severe exophthalmos, respectively. Our results suggest that CT findings may guide TAO clinical therapy recommendations and prognosis. PMID:23638413

  6. MiRNA-21 promotes fibrosis in orbital fibroblasts from thyroid-associated ophthalmopathy

    PubMed Central

    Bo-ding, Tong; Man-Yi, Xiao; Jie-Xi, Zeng

    2015-01-01

    Purpose This study aimed to determine the role of miR-21 in orbital fibroblasts obtained from donors with thyroid-associated ophthalmopathy (TAO) and to elucidate the regulation of fibrosis by miR-21 in the pathological process of TAO. Methods The expression of miR-21 was investigated in orbital tissues from 26 donors with TAO and 10 donors without TAO. Human orbital fibroblasts were cultivated from TAO donors, and the role of miR-21 in orbital fibroblast proliferation, apoptosis, and differentiation was analyzed. Moreover, the effect of transforming growth factor-beta1 (TGF-?1) on miR-21 expression was also analyzed. In addition, the regulation of miR-21 in TGF-?1-induced collagen production was determined. Results The expression of miR-21 in orbital fibroblasts from TAO was higher than in donors without TAO. Additional experiments demonstrated that miR-21 enhanced proliferation, decreased apoptosis, and promoted differentiation in TAO orbital fibroblasts. Moreover, this study also showed that TGF-?1 induced miR-21 expression in a time- and dose-dependent manner and miR-21 promoted collagen I mRNA expression and total collagen production induced by TGF-?1. Additionally, miR-21 activated the TGF-?1/Smad signaling pathway by enhancing Smad3 phosphorylation. Conclusions The present study shows that miR-21 regulates cell proliferation, apoptosis, and differentiation in orbital fibroblasts from TAO, and acts as a mediator in TGF-?1-induced collagen production. These data predict a close association between miR-21 and orbital muscle fibrosis, and provide a novel therapeutic target for TAO.

  7. Contrast Sensitivity of Thyroid Associated Ophthalmopathy Patients without Obvious Optic Neuropathy

    PubMed Central

    Beden, Ümit; Kaya, Sümeyra; Yeter, Volkan; Erkan, Dilek

    2013-01-01

    Purpose. To compare the contrast sensitivity levels of thyroid associated ophthalmopathy (TAO) patients without obvious optic neuropathy with those of healthy people. Methods. Forty eyes of 20 TAO patients without dysthyroid optic neuropathy and 40 eyes of 20 healthy subjects were evaluated in this prospective case-controlled study. The contrast sensitivity functions (CSFs) of all subjects were measured by the functional acuity contrast test (FACT) in five frequencies which were 1,5 cpd (A), 3 cpd (B), 6 cpd (C), 12 cpd (D), and 18 cpd (E). Results were compared for both groups, and a correlation of CSF with Hertel and clinical activity scores was assessed. Results. There was no statistically significant difference between TAO patients and control groups for age and sex. TAO patients had lower levels than the control group in all the frequencies of CSFs (P < 0.05) and the difference in contrast sensitivity functions between the groups seems to be more significant in higher frequencies (B, C, D, and E) (P < 0.001). Conclusions. TAO patients without DON can have contrast sensitivity loss and this would probably imply subtle optic nerve dysfunction in early disease phase. PMID:24453927

  8. Patient Information in Graves' Disease and Thyroid-Associated Ophthalmopathy: Readability Assessment of Online Resources

    PubMed Central

    Denniston, Alastair K.; Boelaert, Kristien; Franklyn, Jayne A.; Durrani, Omar M.

    2014-01-01

    Background: The Internet is a vital source of information for patients hoping to learn more about their disease. Health literacy of the general population is known to be poor, with the U.S. Department of Health and Human Services (USDHHS) recommending that patient-oriented literature be written at a fourth- to sixth-grade reading level to optimize comprehensibility. In this study we assessed the readability of online literature specifically for Graves' disease (GD) and thyroid-associated ophthalmopathy (TAO). Methods: Readability of the content of the top 20 English-language GD patient-oriented online resources and top 30 of the equivalent TAO resources returned by Google search was analyzed. Web pages were identified using the Google search terms “Graves' disease” and “Thyroid-Associated Ophthalmopathy,” respectively. Extraneous text (e.g., hyperlinks, affiliations, disclaimers) was removed. Relevant text proceeded to readability analysis using four validated measures: Flesch Reading Ease Score, Flesch-Kincaid Grade Level, Simple Measure of Gobbledygook, and Gunning-Fog Index. Readability was compared with USDHHS standards. Results: Overall, median word count (with interquartile range [IQR] and range) was 990 (IQR 846, 195–3867), with a median of 18 words per sentence (IQR 4.0, 7.5–28). Median Flesch Reading Ease Score was 46 (IQR 13, 24–64), Flesch-Kincaid Grade Level 11 (IQR 3.0, 7.2–17), Simple Measure of Gobbledygook 13 (IQR 2.0, 9.6–17), and Gunning-Fog Index 13 (IQR 3.0, 9.2–19), each equivalent to a reading level of >11th grade and “difficult” on the USDHHS classification. None of the web pages evaluated had readability scores in accordance with published guidelines. There was no significant difference with the country of origin of each web page, website commercial status, or with pages predominantly focused on GD or TAO. Conclusions: Readability scores for online GD and TAO patient-focused materials are inferior to those recommended. Screening of this online material, as well as subsequent revision, is crucial to increase future patient knowledge, satisfaction, and compliance. PMID:24040878

  9. Atypical Presentation of Hashimoto’s Disease in an Adolescent: Thyroid-Associated Ophthalmopathy

    PubMed Central

    K?rm?z?bekmez, Heves; Ye?iltepe Mutlu, Rahime Gül; Dursun, Fatma; Günay, Murat

    2014-01-01

    Hashitoxicosis is generally differentiated from Graves’ hyperthyroidism by its shorter course and absence of ophthalmopathy. In this case report, we describe an adolescent girl who presented with significant clinical findings of hyperthyroidism, a diffuse goiter with homogenously increased uptake in scintigraphy, and with ocular findings of ophthalmopathy. The thyroid stimulating hormone receptor antibody test was positive, and the family history revealed thyroid-associated ophthalmopathy. Clinical findings supported the diagnosis of Hashimoto’s disease (HD) in the follow-up period. Radioactive iodine uptake investigation was found to be a reliable method for differential diagnosis. Attention was drawn to the rarity of pediatric cases of HD who present with ophthalmopathy. PMID:25541900

  10. Orbital Fibroblast Heterogeneity May Determine the Clinical Presentation of Thyroid Associated Ophthalmopathy

    Microsoft Academic Search

    TERRY J. SMITH; LAURA KOUMAS; ANNEMARIE GAGNON; ANDREA BELL; GREGORY D. SEMPOWSKI; RICHARD P. PHIPPS; ALEXANDER SORISKY

    Thyroid-associated ophthalmopathy, a process in which the orbital tissues become inflamed and are remodeled, occurs with a variable presentation. In some patients, eye muscle enlargement predominates. In others, the connective\\/adipose tissue enlargement appears the more significant problem. Or- bital fibroblasts exhibit heterogeneous phenotypes in culture. Here we report that fibroblasts derived from the connective\\/ adipose tissue depot are distinct from

  11. Increased Expression of TSH Receptor by Fibrocytes in Thyroid-Associated Ophthalmopathy Leads to Chemokine Production

    PubMed Central

    Gillespie, Erin F.; Papageorgiou, Konstantinos I.; Fernando, Roshini; Raychaudhuri, Nupur; Cockerham, Kimberly P.; Charara, Laya K.; Goncalves, Allan C. P.; Zhao, Shuang-Xia; Ginter, Anna; Lu, Ying; Smith, Terry J.

    2012-01-01

    Context: The molecular basis for anatomically dispersed clinical manifestations in Graves' disease (GD) eludes our understanding. Bone marrow-derived, pluripotent fibrocytes represent a subset of peripheral blood mononuclear cells and infiltrate the orbital and thyroid tissues in GD. These cells may be involved in the pathogenesis of thyroid-associated ophthalmopathy (TAO). Objective: The objective of the study was to quantify fibrocyte display of functional cell surface TSH receptor (TSHR), identify the profile of chemokines they express after TSHR activation, and determine whether circulating TSHR+ peripheral blood fibrocytes are more frequent in situ in patients with TAO. Design/Setting/Participants: Using a newly developed technique, fibrocytes were directly identified in peripheral blood from 31 patients with TAO and 19 healthy subjects receiving care at a multidisciplinary academic center. Main Outcome Measures: The frequency in situ of fibrocytes (collagen 1+, CD45+, CD34+, CD14+, CD86+ peripheral blood mononuclear cells) was assessed by multiparameter flow cytometry and correlated to clinical disease activity and smoking status. Levels of TSHR-displaying fibrocytes and their response to TSH and TSHR-activating antibody, M22, were measured by flow cytometry, Luminex, and real-time PCR. Results: The levels of TSHR expression by fibrocytes are substantially higher than those found in orbital fibroblasts. Moreover, the frequency of TSHR+ fibrocytes in patients with TAO was greater than that in healthy subjects in situ. Their abundance is not influenced by disease activity or smoking history. These cells produce high levels of several cytokines and chemokines including IL-8, regulated upon activation, normal T cell expressed and secreted, and monocyte chemoattractant protein-1 when treated with TSH or M22. TSH induces IL-8 production at the pretranslational level. This induced cytokine can be detected in intact fibrocytes ex vivo. Conclusions: Frequency of circulating TSHR+ fibrocytes is markedly increased in patients with TAO, and they express proinflammatory chemokines in response to TSH. Because they infiltrate both orbit and thyroid in GD, they may represent the link between systemic immunoreactivity and organ-specific autoimmunity. PMID:22399514

  12. Presence of thyroid-associated ophthalmopathy in Hashimoto's thyroiditis

    PubMed Central

    Kan, Emrah; Kan, Elif Kilic; Ecemis, Gülcin; Colak, Ramis

    2014-01-01

    AIM To determine the prevalence of ophthalmopathy in Hashimoto's patients and to make a comparison in subgroups of patients METHODS The study involved 110 Hashimoto's thyroiditis patients and 50 control subjects attending to the endocrinology department of the hospital. Subgroup classification of patients was made as euthyroid, subclinic and clinic in Hashimato's thyroiditis. All patients were evaluated by a single experienced ophthalmologist for the prevalence and characteristics of eye signs. RESULTS The overall prevalences of eye changes were 22.7% (25 patients) in patients and 4% (2 persons) in control subjects respectively (P=0.002). In patients the most common symptom was retrobulbar eye pain with or without any eye movement. Thirteen patients had significant upper eyelid retraction (11.8%). Six patients had eye muscle dysfunction as reduced eye movements in up gaze. In control patients one person had proptosis and another had lid retraction. The clinical activity score and classification of the ophthalmopathy did not show any significant differences among subgroups. CONCLUSION The eye signs were mostly mild (22.7%) and the most common eye sign was the presence of upper eyelid retraction (11.8%). Additionally six patients had eye muscle dysfunction as reduced eye movements in up gaze. Therefore we recommend to make a routine ophthalmic examination in Hashimoto's thyroiditis patients in order not to omit the associated ophthalmopathy. PMID:25161935

  13. Benzylideneacetophenone derivatives attenuate IFN-?-induced IP-10/CXCL10 production in orbital fibroblasts of patients with thyroid-associated ophthalmopathy through STAT-1 inhibition

    PubMed Central

    Lee, Sung-Hee; Lim, Seul Ye; Choi, Ji Ha; Jung, Jae-Chul; Oh, Seikwan; Kook, Koung Hoon; Choi, Youn-Hee

    2014-01-01

    The aim of the present study was to identify a new candidate anti-inflammatory compound for use in the active stage of thyroid-associated ophthalmopathy (TAO). Benzylideneacetophenone compound JC3 [(2E)-3-(4-hydroxy-3-methoxyphenyl)phenylpro-2-en-l-one] was synthesized based on a structural modification of yakuchinone B, a constituent of the seeds of Alpinia oxyphylla, which belongs to the ginger family (Zingiberaceae), has been widely used in folk medicine as an anti-inflammatory phytochemical. Orbital fibroblasts were primarily cultured from patients with TAO, and the potential of JC3 to suppress the interferon (IFN)-?-induced protein (IP)-10/CXCL10 production in these cells was determined. IFN-? strongly increased the level of IP-10/CXCL10 in orbital fibroblasts from patients with TAO. JC3 exerted a significant inhibitory effect on the IFN-?-induced increase in IP-10/CXCL10 in a dose-dependent manner; its potency was greater than that of an identical concentration of yakuchinone B with no toxicity to cells at the concentration range used. Moreover, the constructed dimer and trimer polystructures of JC3, showed greater potency than JC3 in suppressing the IFN-?-induced production of IP-10/CXCL10. JC3 significantly attenuated the IP-10/CXCL10 mRNA expression induced by IFN-?, and a gel-shift assay showed that JC3 suppressed IFN-?-induced DNA binding of signal transducer and activator of transcription-1 (STAT-1) in TAO orbital fibroblasts. Our results provide initial evidence that the JC3 compound reduces the levels of IP-10/CXCL10 protein and mRNA induced by IFN-? in orbital fibroblasts of TAO patients. Therefore, JC3 might be considered as a future candidate for therapeutic application in TAO that exerts its effects by modulating the pathogenic mechanisms in orbital fibroblasts. PMID:24924312

  14. Thyrotropin Receptor and CD40 Mediate Interleukin-8 Expression in Fibrocytes: Implications for Thyroid-Associated Ophthalmopathy (An American Ophthalmological Society Thesis)

    PubMed Central

    Douglas, Raymond S.; Mester, Tünde; Ginter, Anna; Kim, Denise S.

    2014-01-01

    Purpose: To better understand the pathogenesis of thyroid-associated orbitopathy (TAO) through elucidating the role of thyrotropin receptor (TSHR) and CD40 in the expression of interleukin-8 (IL-8) in peripheral blood fibrocytes. Fibrocytes infiltrate the orbit of patients with TAO, where they differentiate into fibroblasts. Fibrocyte precursors occur with increased frequency in the peripheral blood expressing TSHR and CD40 in TAO patients. We hypothesize that in vitro derived fibrocytes and peripheral blood fibrocyte precursors express proinflammatory chemoattractant molecules including IL-8 initiated by TSHR and CD40 signaling. Since nearly all TAO patients express activating antibodies to TSHR, this is particularly relevant for activation of peripheral blood fibrocytes. Methods: TSHR and CD40 expression on peripheral blood fibrocytes was determined by flow cytometry. IL-8 RNA was quantitated by real-time polymerase chain reaction. IL-8 protein production was measured by Luminex and flow cytometry. Thyroid-stimulating hormone and CD40 ligand–stimulated phosphorylation of Akt in peripheral blood fibrocytes was studied by flow cytometry. Results: Both TSHR- and CD40-mediated signaling lead to IL-8 expression in mature fibrocytes. Fibrocyte precursors assayed directly from circulating peripheral blood demonstrate intracellular IL-8 expression with addition of thyroid-stimulating hormone or CD40 ligand. TSHR- and CD40-induced IL-8 production is mediated by Akt phosphorylation. Conclusions: Peripheral blood TSHR+ and CD40+ fibrocytes express IL-8 and may promote the recruitment of inflammatory cells, mitogenesis, and tissue remodeling in TAO. TSHR- and CD40-mediated IL-8 signaling is mediated by Akt. Delineating the molecular mechanisms of fibrocyte immune function may provide potential therapeutic targets for TAO. PMID:25411513

  15. Thyroid associated orbitopathy

    PubMed Central

    Maheshwari, Rajat; Weis, Ezekiel

    2012-01-01

    Thyroid associated orbitopathy, also known as Graves’ orbitopathy, is typically a self-limiting autoimmune process associated with dysthyroid states. The clinical presentation may vary from very mild disease to severe irreversible sight-threatening complications. Despite ongoing basic science and clinical research, the pathogenesis and highly effective therapeutic strategies remain elusive. The present article reviews the pathophysiology, clinical presentation, and management of this common, yet poorly understood disease, which remains a challenge to the ophthalmologist. PMID:22446901

  16. Update on advanced imaging options for thyroid-associated orbitopathy

    PubMed Central

    Rabinowitz, Michael P.; Carrasco, Jacqueline R.

    2012-01-01

    Thyroid-associated orbitopathy (TAO) is a diverse spectrum of signs and symptoms that appears to have immunologic and pathologic causative factors as diverse as its clinical presentations. Lymphocytes, hormones, and cytokines affect orbital fibroblasts and other similar cells, which exert their effects on orbital tissues, including the extraocular muscles, orbital fat, and optic nerve. This complicated inflammatory cascade and the myriad of clinical findings that result contributes to the active phase of TAO. The distinction between the active and inactive phases of TAO is an important one, as the proper treatment will depend on the disease phase and degree thereof. Several clinical grading scales and scores have been established to help qualify and quantify the disease severity. Aiding clinical exam and acumen, proper and reproducible imaging of the orbit and ocular adnexa is incredibly important to the management of TAO. Orbital ultrasound, computed tomography, magnetic resonance imaging, and scintigraphy each have unique abilities, including quantifying orbital changes, assessing disease activity, correlating orbital findings with clinical changes, guiding appropriate treatment, and monitoring therapeutic responses. Further, study ease, accessibility, cost, sensitivity, specificity, reproducibility, and risks are all important considerations in picking the right test with which to diagnose and follow TAO. This analysis will provide a review of orbital imaging for TAO, including the mechanism of each imaging technique as well as their rationales, advantages, disadvantages, and utilities. PMID:23961023

  17. Thyroid-associated orbitopathy is linked to gastrointestinal autoimmunity.

    PubMed

    Ponto, K A; Schuppan, D; Zwiener, I; Binder, H; Mirshahi, A; Diana, T; Pitz, S; Pfeiffer, N; Kahaly, G J

    2014-10-01

    Common autoimmune disorders tend to co-exist in the same subjects and cluster in families. The objective of this study was to determine the prevalence of autoimmune co-morbidity in patients with autoimmune thyroid disease (AITD) with and without thyroid-associated orbitopathy (TAO). This was a cross-sectional study conducted at an academic tertiary referral centre. Of 1310 patients with AITD [n?=?777 or 59% with Graves' disease (GD) and n?=?533, 41% with Hashimoto's thyroiditis (HT)] followed at a specialized joint thyroid-eye out-patient clinic, 176 (13·4%) had an adult type of the autoimmune polyglandular syndrome, 129 (9·8%) type 1 diabetes, 111 (8·5%) coeliac disease, 60 (4·6%) type A autoimmune gastritis, 57 (4·4%) vitiligo and 25 (1·9%) Addison's disease. Coeliac disease and autoimmune gastritis were associated positively with GD [odds ratio (OR)?=?2·18; P?=?0·002 and OR?=?6·52; P?TAO, 584 (95·7%) and 26 (4·3%) had GD and HT, respectively (P?TAO was most prevalent in GD patients with coeliac disease (94%, OR?=?1·87, P?TAO while type 1 diabetes, Addison's disease and alopecia areata were protective for TAO. In patients with TAO, coeliac disease is the most prevalent co-morbid autoimmune condition and rates are increased compared to GD patients without TAO. PMID:24903731

  18. Th1/Th2 cytokines in patients with Graves' disease with or without ophthalmopathy.

    PubMed

    Esfahanian, Fatemeh; Naimi, Effat; Doroodgar, Farideh; Jadali, Zohre

    2013-06-01

    About 25-50% of Graves' disease (GD) patients develop thyroid eye diseases, which is associated with inflammatory process and abnormalities in the levels of several cytokines in orbital tissues in GD. The aim of this study was to determine the Th1 and Th2 serum cytokines in patients with GD with or without ophthalmopathy. Serum levels of cytokines and autoantibodies including Interferon-gamma (IFN-?), Interleukin-2 (IL-2), Interleukin-4 (IL-4), Interleukin-10 (IL-10), TSH receptor autoantibody (TRAb), thyroid peroxidase antibody (TPOAb) and thyroglobulin antibody(TgAb) were measured by enzyme linked immunosorbent assay(ELISA) in 34 patients with GD and in 33 normal controls. Patients were also divided in two subgroups: 18 cases with ophthalmopathy and 16 cases without ophthalmopathy. Cytokine and antibody responses were analyzed in both groups. Compared with control subjects, patients with GD showed elevated levels of IL-2 and IL-10. IFN-? levels were lower in patients in comparison to the controls. No significant differences were found between patients and controls regarding the IL-4. There was no statistically significant difference in cytokine levels between those with or without ophthalmopathy. Quantitative-cytokine analysis demonstrated that a combination of Th1 and Th2 cytokines may contribute to the pathogenesis of GD. These results also indicate that IL-10, but not IL-4, is related to the moderate and severe forms of thyroid associated ophthalmophathy. PMID:23754356

  19. Thyroid-associated autoimmune coagulation disorders

    Microsoft Academic Search

    Massimo Franchini; Giuseppe Lippi; Franco Manzato; Pier Paolo Vescovi

    2010-01-01

    Abnormalities of blood coagulation are not rarely observed in patients with thyroid dysfunctions and may range from subclinical\\u000a laboratory abnormalities to clinically significant hemorrhagic or thrombotic complications. In this review, we summarize the\\u000a current knowledge on thyroid-associated autoimmune coagulation disorders (i.e., autoimmune thrombocytopenic purpura, antiphospholipid\\u000a syndrome, and autoantibodies against coagulation factor VIII) and discuss their laboratory characteristics, clinical impact,\\u000a and

  20. Characterization and outcomes of repeat orbital decompression for thyroid-associated orbitopathy.

    PubMed

    Zhang-Nunes, Sandy X; Dang, Sabin; Garneau, Helene Chokron; Hwang, Catherine; Isaacs, David; Chang, Shu-Hong; Goldberg, Robert

    2015-04-01

    Orbital decompression for thyroid-associated orbitopathy (TAO) is commonly performed for disfiguring proptosis, congestion, and optic neuropathy. Although one decompression typically achieves goals, a small percentage requires repeat decompression. We performed a 10-year retrospective chart review of all orbital decompressions for TAO at a single tertiary referral institution. Four-hundred and ninety-five orbits (330 patients) were decompressed for TAO, with 45 orbits (37 patients) requiring repeat decompression. We reviewed the repeat cases for indications, clinical activity scores, approach, walls decompressed, and outcomes. Nine percent of orbits required repeat decompression for proptosis (70%), optic neuropathy (25%) or congestion (45%). Sixty-four percent were for recurrence of disease, 36% were for suboptimal decompression. Three incisional approaches were used: lateral upper eyelid crease, inferior transconjunctival, and transcaruncular, with inferior transconjunctival being most common. Of the three walls removed, deep lateral, inferior, and medial, the deep lateral wall was most common (51%). A repeat lateral decompression was the most frequent pattern. Of 37 patients requiring repeat decompression, 40% had diplopia prior to repeat, and an additional 24% developed diplopia after the repeat. Whereas previous studies published by our group cited only 2.6% of deep lateral wall orbital decompressions leading to new-onset primary gaze diplopia, repeat orbital decompressions have a much higher rate of post-operative diplopia. The new onset primary gaze diplopia after repeat decompression group had a higher average preoperative CAS (3.3 vs. 2.4, p?

  1. Graves' ophthalmopathy: epidemiology and natural history.

    PubMed

    Hiromatsu, Yuji; Eguchi, Hiroyuki; Tani, Junichi; Kasaoka, Masataka; Teshima, Yasuo

    2014-01-01

    Graves' ophthalmopathy (GO) is an autoimmune disorder of the orbit that is clinically relevant in 25-50% of patients with Graves' disease and 2% of patients with chronic thyroiditis. The age-adjusted annual incidence of clinically relevant GO is 16 per 100,000 population in women and 2.9 in men. At the onset of ophthalmopathy, 80-90% of patients have hyperthyroidism, with the rest having euthyroidism or hypothyroidism. The natural history of GO consists of two phases: an active inflammatory phase and a static phase. Anti-inflammatory therapy is indicated for the first phase of GO. Approximately 5% of patients experience late reactivation of GO. Asians appear to have less severe manifestations, with milder orbital edema, proptosis and muscle restriction. Genetic, anatomic and environmental factors influence the development of GO. Aging, thyroid dysfunction, thyroid stimulating hormone (TSH) receptor antibodies, smoking and radioiodine treatment for hyperthyroidism also influence the development and course of GO. PMID:24583420

  2. Mechanisms of Immune Damage in Graves’ Ophthalmopathy

    Microsoft Academic Search

    Yuji Hiromatsu; Pei Wen Wang; Len Wosu; Jacques How; Jack R. Wall

    1987-01-01

    We have studied the role of immunologically mediated cytotoxicity in the orbital tissue damage of Graves’ ophthalmopathy. Antibody-dependent cell-mediated cytotoxicity (ADCC) against eye muscle (EM) cells and orbital fibroblasts (OF) was demonstrated in a small proportion of patients, all of whom had severe, recent disease. Antibody-mediated (complement-dependent) cytotoxicity against OF was found in only a few patients. No patients showed

  3. San Geronimo de Taos (Taos Pueblo).

    ERIC Educational Resources Information Center

    Kauppinen, Heta

    1989-01-01

    This lesson plan introduces high school students to pueblo architecture. Students will learn about pueblo architecture and its cultural tradition; discuss architectural characteristics and aesthetics in San Geronimo de Taos; examine the pueblo as a living environment; explore adobe pueblo structure in clay; and study Hopi, Zuni, and Pueblo…

  4. The Influence of Prior Hyperthyroidism on Euthyroid Graves' Ophthalmopathy

    PubMed Central

    Mombaerts, Ilse

    2014-01-01

    Background. To investigate the influence of previous exposure to elevated thyroid hormones in euthyroid Graves' ophthalmopathy. Design. Retrospective, observational case series in university setting Median follow-up of 1 year with ranges of 0,8–7,6 years. Study performance of 10 years. Participants. We reviewed the clinical records of 731 Graves' ophthalmopathy patients. There were 88 (12%) patients with onset of Graves' ophthalmopathy during euthyroidism: 37 (5%) patients had ophthalmopathy without known history of thyroid dysfunction (group A) and 51 patients (6%) had onset of ophthalmopathy 6 months or more euthyroid after completion of antithyroid therapy (group B). Main Outcome Measures. Graves' ophthalmopathy was graded using the EUGOGO severity criteria. Unilaterality was investigated. TSH receptor antibody and thyroid peroxidase antibody were measured as markers of Graves' disease. Results. Group A had more often a normal ocular motility (46%) and less proptosis (14 ± 4?mm) compared to group B (22%, 16 ± 4?mm) (P = 0.032 and 0.028, resp.). TSH receptor antibody was more frequently elevated in group B (94%) than in group A (17%) (P < 0.001). Conclusion. Patients with euthyroid Graves' ophthalmopathy present more often with ocular muscle restriction and proptosis when previously exposed to elevated thyroid hormones. PMID:25045529

  5. The evaluation and treatment of graves ophthalmopathy.

    PubMed

    Stan, Marius N; Garrity, James A; Bahn, Rebecca S

    2012-03-01

    Optimum care of the patient with Graves ophthalmopathy (GO) is achieved through teamwork between the endocrinologist and ophthalmologist, with input from ancillary specialists as needed. Clinical evaluation should include determination of both the severity and the activity of the disease. It is important to assess early in the evaluation the impact of the disease on the patient's quality of life and their priorities and expectations regarding management. Once this information has been gathered, careful discussion between patient and physicians can define the management plan. This article reviews the pathophysiology, epidemiology, evaluation, and management of GO. PMID:22443978

  6. Teaching in the Tao.

    ERIC Educational Resources Information Center

    Christie, Patrick

    This book shares the philosophy that what a teacher learned through the martial arts form, Aikido, allowed him to look beyond aggressive acts without responding aggressively himself, viewing the student behind the angry behavior. The teacher notes that compassion works better than any form of discipline he has ever encountered in education. Tao,…

  7. Radiation retinopathy after orbital irradiation for Graves' ophthalmopathy

    SciTech Connect

    Kinyoun, J.L.; Kalina, R.E.; Brower, S.A.; Mills, R.P.; Johnson, R.H.

    1984-10-01

    Recent reports indicate that orbital irradiation for Graves' ophthalmopathy is sometimes beneficial, particularly for dysthyroid optic neuropathy, and is not associated with serious complications. We are aware, however, of four patients who were found to have radiation retinopathy after orbital irradiation for Grave's ophthalmopathy. All four patients have decreased central acuity, and three of the four are legally blind in one or both eyes. Computer reconstruction of the dosimetry, based on computed tomography and beam profiles, shows that errors in dosage calculations and radiotherapy technique probably account for the radiation retinopathy in three of the four patients. Radiotherapy for Graves' ophthalmopathy should be administered only by competent radiotherapists who are experienced in the treatment of this disease. Similar errors in dosage calculations and treatment techniques may account for other reports of radiation retinopathy after reportedly safe dosages.

  8. Graves' ophthalmopathy evaluated by infrared eye-movement recordings

    SciTech Connect

    Feldon, S.E.; Unsoeld, R.

    1982-02-01

    Thirteen patients with varying degrees of Graves' ophthalmopathy were examined using high-resolution infrared oculography to determine peak velocities for horizontal eye movements between 3 degrees and 30 degrees. As severity of the orbital disease increased, peak velocities became substantially lower. Vertical-muscle surgery failed to have any effect on peak velocity of horizontal eye movements. In contrast, orbital decompression caused notable improvement in peak velocity of eye movements. Eye-movement recordings, which provide a measure of extraocular muscle function rather than structure, may provide a safe, sensitive, and accurate method for classifying and following up patients with Graves' ophthalmopathy.

  9. Clinical Significance of Saccade Analysis in Early Active Graves' Ophthalmopathy

    Microsoft Academic Search

    Hermann Dieter Schworm; Armin Ernst Heufelder; Andrea Kunze; Esther Welge; Klaus-Peter Boergen

    2000-01-01

    PURPOSE. To assess whether saccadic eye movements show distinct changes in patients with early active Graves' ophthalmopathy (GO), which could serve as a diagnostic tool for early detection and treatment. METHODS. Each of two prospective studies included 10 patients with early acute GO and 10 age- and sex-matched control subjects. In the explorative study (ES) 15 dynamic parameters of saccades

  10. Treatment of Graves' disease and the course of ophthalmopathy

    SciTech Connect

    Sridama, V.; DeGroot, L.J.

    1989-07-01

    Contradictory results have been obtained with regards to the effect of various treatment modes on the exacerbation of Graves' ophthalmopathy, probably because the number of patients in each study was small and some studies were analyzed only in relation to one type of treatment. To circument these problems, we studied the course of Graves' ophthalmopathy after various modes of therapy for thyrotoxicosis among 537 patients with Graves' disease. A total of 537 patients with Graves' disease were prospectively studied over an 11-year period. Thirty-one patients were lost to follow-up during the first six months after treatment and were excluded from the study. Of those remaining, 426 received one form of treatment, 79 received two kinds of therapy, and one received three kinds of therapy. Thus, surgical treatments numbered 164, radioactive iodine-131 (/sup 13/1I) treatments numbered 241, and medical treatments numbered 182. Ocular signs were considered improved or exacerbated by the following criteria: decrement or increment of the exophthalmos of 2 mm or more, improvement or deterioration of visual acuity, and regression or progression of extraocular muscle involvement causing diplopia. Among patients who did not have infiltrative ophthalmopathy before treatment, there was no difference in the occurrence of posttreatment exophthalmos in the surgically, medically, and 131I-treated patients (7.1%, 6.7%, and 4.9%, respectively). The incidence and the degree of progression of ophthalmopathy in patients who already had exophthalmos before treatment were similar in the medically, surgically, and 131I-treated groups (19.2%, 19.8%, and 22.7%, respectively). Most of the progression occurred in the posttreatment euthyroid stage. The incidence of improvement of ophthalmopathy was also similar 14.1%, 12.6%, and 12.3% in the medically, surgically, and 131I-treated patients.

  11. The effect of subtotal thyroidectomy on Graves' ophthalmopathy

    Microsoft Academic Search

    Michael D. Levitt; Anthony J. Edis; Ross Agnello; Clement C. McCormick

    1988-01-01

    Nineteen unselected patients undergoing subtotal thyroidectomy (STT) for Graves' disease were submitted to thorough ophthalmologic assessment before and after (mean, 10 mo) thyroid surgery. All clinical examinations were performed by the same observer and findings were scored according to the American Thyroid Association (“NOSPECS”) classification. Orbital computed tomography (CT) scans were performed in all patients prior to surgery and again

  12. Graves disease with ophthalmopathy following radiotherapy for Hodgkin's disease

    SciTech Connect

    Jacobson, D.R.; Fleming, B.J.

    1984-12-01

    The number of patients achieving long-term survival following neck irradiation for Hodgkin's disease and other malignancies is increasing. Paralleling this increase in survivors is the development of late complications of the therapy itself. Eleven patients have previously been reported who developed Graves ophthalmopathy 18 months to seven years after receiving neck radiotherapy for nonthyroidal malignancies. The seven patients who had HLA typing were all HLA-B8 negative, despite the reported association of the HLA-B8 antigen with Graves disease. A patient who is HLA-B8 positive who developed Graves ophthalmopathy and hyperthyroidism nine years after receiving mantle radiotherapy for Hodgkin's disease is reported. It is recommended that Graves disease be included among the thyroid diseases that receive consideration during follow-up of patients who have received mantle radiotherapy.

  13. The relationship between Graves’ ophthalmopathy and dry eye syndrome

    PubMed Central

    Selter, Jessica H; Gire, Anisa I; Sikder, Shameema

    2015-01-01

    Background A complex relationship between Graves’ ophthalmopathy (GO) and dry eye syndrome exists. New research brings more insight into the association between these two diseases. Methods A review of the literature was conducted using the query terms “Graves’ Ophthalmopathy”, “Thyroid Eye Disease”, and “Dry Eye” in MedLine (PubMed) and Scopus. A total of 55 papers were reviewed. Case reports were excluded. Conclusion This review paper shows the close relationship between dry eye syndrome and GO. The underlying mechanisms behind their association suggest mechanical impairment of orbital muscles and immune-mediated lacrimal gland dysfunction as the causes of dry eye in GO patients. However, there are a variety of treatment options available for patients with GO with signs of dry eye, which help combat this issue. PMID:25584018

  14. QUALITY OF LIFE IN PATIENTS WITH GRAVES OPHTHALMOPATHY

    PubMed Central

    Yeatts, R. Patrick

    2005-01-01

    Purpose To assess the quality of life in patients with Graves ophthalmopathy by means of a prospective questionnaire with validation. Methods A questionnaire containing 105 items was sent to 325 patients seen in our university-based oculoplastic clinic. Two hundred three questionnaires were returned and were suitable for analysis. Fifty-three consecutive patients with Graves disease who presented to the clinic for examination also completed the questionnaire. The questionnaire was validated by administering it to 33 healthy subjects who had no history of Graves disease or thyroid disorder. The results were compared with those of normal subjects and with national norms for visually impaired populations. The relationship of individual questionnaire items to measures of clinical severity was subsequently assessed. Results Patients with Graves ophthalmopathy report greater impairment in both physical (44.4 versus 51.9; P < .001) and mental (43.8 versus 51.8; P < .001) health; poorer self- image (P < .001); and significantly more disturbance in their sleep, social function, and work function (P < .001) than controls. Afflicted patients also experience significantly more diplopia, blurred vision, and dry eye symptoms than controls (P < .001). Individual questionnaire items were found to correlate with clinical disease severity scores and were used to establish a Graves ophthalmopathy quality-of-life questionnaire with disease severity validation. Conclusions Patients with Graves disease are significantly impaired in their social and vocational function because of the ophthalmic manifestations of the disease. A short questionnaire that correlates with clinical measures of disease severity may be a useful measure of quality of life in this disease. PMID:17057811

  15. Reactivation of thyroid associated orbitopathy following trauma with intraorbital foreign body.

    PubMed

    Papakostas, Thanos D; Lee, Nahyoung Grace; Callahan, Alison B; Freitag, Suzanne K

    2015-02-01

    A 63-year-old female with mild, bilateral, stable thyroid-associated orbitopathy sustained trauma resulting in glass foreign bodies embedded on the left ocular surface and left lateral orbital extraconal and intraconal space. After 2 orbitotomies including a failed attempt to remove the intraconal foreign body and poor response to oral steroids, she developed severe, progressive left periorbital edema and 9?mm of relative proptosis. Serial, post-operative imaging demonstrated worsening inflammatory changes along the surgical tract, which slowly improved over several months, with simultaneously worsening proptosis and enlargement of the left inferior and medial rectus muscles consistent with worsening thyroid orbitopathy. She subsequently underwent unilateral 3-wall orbital decompression with improvement in her symptoms. Periorbital trauma with orbital foreign bodies and related surgical trauma may result in reactivation of thyroid-associated orbitopathy. PMID:25208306

  16. The association of carotid cavernous fistula with Graves’ ophthalmopathy

    PubMed Central

    Celik, Ozlem; Buyuktas, Deram; Islak, Civan; Sarici, A Murat; Gundogdu, A Sadi

    2013-01-01

    Graves’ ophthalmopathy (GO) is one of the frequent manifestations of the disorder which is an inflammatory process due to fibroblast infiltration, fibroblast proliferation and accumulation of glycosaminoglycans. Eye irritation, dryness, excessive tearing, visual blurring, diplopia, pain, visual loss, retroorbital discomfort are the symptoms and they can mimic carotid cavernous fistulas. Carotid cavernous fistulas are abnormal communications between the carotid arterial system and the cavernous sinus. The clinical manifestations of GO can mimic the signs of carotid cavernous fistulas. Carotid cavernous fistulas should be considered in the differential diagnosis of the GO patients especially who are not responding to the standard treatment and when there is a unilateral or asymmetric eye involvement. Here we report the second case report with concurrent occurrence of GO and carotid cavernous fistula in the literature. PMID:23571267

  17. Use of corticosteroids to prevent progression of Graves' ophthalmopathy after radioiodine therapy for hyperthyroidism

    SciTech Connect

    Bartalena, L.; Marcocci, C.; Bogazzi, F.; Panicucci, M.; Lepri, A.; Pinchera, A. (Univ. of Pisa (Italy))

    1989-11-16

    We studied the effects of radioiodine treatment of hyperthyroidism due to Graves' disease on Graves' ophthalmopathy and the possible protective role of corticosteroids. Between June 1985 and June 1988, 26 patients were randomly assigned to treatment with radioiodine alone (group 1) and 26 to treatment with this agent and concomitant administration of systemic prednisone for four months (group 2). The initial dose of prednisone was 0.4 to 0.5 mg per kilogram of body weight for one month; the drug was gradually withdrawn over the next three months. All patients were evaluated at 3-month intervals for 18 months after they underwent radioiodine therapy. Ocular changes were assessed with the ophthalmopathy index; patients with moderate-to-severe changes (scores greater than or equal to 4) were excluded from the study. Before treatment, 10 patients in group 1 and 5 in group 2 had no evidence of ophthalmopathy: in none of them did ocular symptoms appear after radioiodine therapy. Among the patients in group 1 with an initial ophthalmopathy index greater than or equal to 1, ocular disease worsened in 56 percent (mostly involving soft-tissue changes and extraocular-muscle function) and did not change in 44 percent. In contrast, ophthalmopathy improved in 52 percent and did not change in 48 percent of group 2. The mean ophthalmopathy index increased from 1.5 to 3.0 in group 1 (P less than 0.005) and decreased from 2.2 to 1.3 in group 2 (P less than 0.05). We conclude that systemic corticosteroid treatment prevents the exacerbations of Graves' ophthalmopathy that occur after radioiodine therapy in a substantial proportion of patients with hyperthyroidism who have some degree of ocular involvement before treatment.

  18. WHAT IS GOOD MATHEMATICS? TERENCE TAO

    E-print Network

    Tao, Terence

    WHAT IS GOOD MATHEMATICS? TERENCE TAO to produce good mathematics. B* *ut how does one define "good mathematics", and should one even dare to try are many different types of mathematics which could be designated "good". For insta* *nce, "good

  19. Subclassification of Follicular Neoplasms Recommended by the Japan Thyroid Association Reporting System of Thyroid Cytology

    PubMed Central

    Kakudo, Kennichi; Kameyama, Kaori; Hirokawa, Mitsuyoshi; Katoh, Ryohei; Nakamura, Hirotoshi

    2015-01-01

    Background. The Japan Thyroid Association recently published guidelines for clinical practice for the management of thyroid nodules, which include a diagnostic system for reporting thyroid fine needle aspiration cytology. It is characterized by the subclassification of follicular neoplasms, which is different from other internationally accepted reporting systems. Materials and Methods. This study examined observer variability in the subclassification of follicular neoplasms among 4 reviewers using Papanicolaou-stained smear samples from 20 surgically treated patients with indeterminate cytology. Results. The favor malignant subcategory had high predictive value of malignancy (risk of malignancy: 60–75%) and good agreement among the 4 reviewers (? = 0.7714). Conclusion. These results clearly confirmed that the risk stratification of follicular neoplasms, which was adapted from cytology practice of high-volume thyroid centers in Japan, can provide clinically helpful information to estimate the risk of malignancy and to triage patients for surgery. PMID:25722720

  20. American Thyroid Association Guide to Investigating Thyroid Hormone Economy and Action in Rodent and Cell Models

    PubMed Central

    Anderson, Grant; Forrest, Douglas; Galton, Valerie Anne; Gereben, Balázs; Kim, Brian W.; Kopp, Peter A.; Liao, Xiao Hui; Obregon, Maria Jesus; Peeters, Robin P.; Refetoff, Samuel; Sharlin, David S.; Simonides, Warner S.; Weiss, Roy E.; Williams, Graham R.

    2014-01-01

    Background: An in-depth understanding of the fundamental principles that regulate thyroid hormone homeostasis is critical for the development of new diagnostic and treatment approaches for patients with thyroid disease. Summary: Important clinical practices in use today for the treatment of patients with hypothyroidism, hyperthyroidism, or thyroid cancer are the result of laboratory discoveries made by scientists investigating the most basic aspects of thyroid structure and molecular biology. In this document, a panel of experts commissioned by the American Thyroid Association makes a series of recommendations related to the study of thyroid hormone economy and action. These recommendations are intended to promote standardization of study design, which should in turn increase the comparability and reproducibility of experimental findings. Conclusions: It is expected that adherence to these recommendations by investigators in the field will facilitate progress towards a better understanding of the thyroid gland and thyroid hormone dependent processes. PMID:24001133

  1. Thyroid function. Pathogenesis of Graves ophthalmopathy--a role for TSH-R?

    PubMed

    Wall, Jack R

    2014-05-01

    A new study highlights the complexities of anti-TSH-receptor antibody function and the differences between adult and paediatric patients with Graves disease, adding to the controversy regarding the possible role of these antibodies in the development of ophthalmopathy. PMID:24663219

  2. Update on TAO moored ORG array

    NASA Technical Reports Server (NTRS)

    Freitag, H. Paul

    1994-01-01

    During the Coupled Ocean Atmosphere Response Experiment (COARE) six TAO moorings were equipped with optical rain gauges (ORG's). In late 1993 moorings deployed on the equator at 154E and 157.5E were recovered and not redeployed as they were augmentations to the TAO array for COARE only. In December 1993, four TAO moorings were equipped with ORG's: one each at 2N, 156E and 2S, 156E and ORG doublets on the equator at 0, 156E and 0, 165E. The 2N, 156E mooring has been lost. By the end of April all sites will have been serviced and six refurbished sensors will again be deployed in the same locations.

  3. TAOS/LS1 development final report

    SciTech Connect

    Phipps, G.S.; Gentry, S.M.; Falls, J.M.; Claassen, P.J.; Alder, G.J.

    1997-12-01

    The Laser Sensor No. 1 (LS1) is a system designed and built by Sandia to detect and report laser illumination of an orbiting satellite. It was launched March 1994 as part of the U.S. Air Force Phillips Laboratory, Technology for Autonomous Operational Survivability (TAOS) satellite program. The engineering details of the system are described in this report. Operation characteristics and results have been reserved for inclusion in a classified Air Force report prepared by the TAOS Program Office of Phillips Laboratory.

  4. 2014 European Thyroid Association Guidelines for the Management of Subclinical Hypothyroidism in Pregnancy and in Children

    PubMed Central

    Lazarus, John; Brown, Rosalind S.; Daumerie, Chantal; Hubalewska-Dydejczyk, Alicja; Negro, Roberto; Vaidya, Bijay

    2014-01-01

    This guideline has been produced as the official statement of the European Thyroid Association guideline committee. Subclinical hypothyroidism (SCH) in pregnancy is defined as a thyroid-stimulating hormone (TSH) level above the pregnancy-related reference range with a normal serum thyroxine concentration. Isolated hypothyroxinaemia (defined as a thyroxine level below the 2.5th centile of the pregnancy-related reference range with a normal TSH level) is also recognized in pregnancy. In the majority of SCH the cause is autoimmune thyroiditis but may also be due to iodine deficiency. The cause of isolated hypothyroxinaemia is usually not apparent, but iodine deficiency may be a factor. SCH and isolated hypothyroxinaemia are both associated with adverse obstetric outcomes. Levothyroxine therapy may ameliorate some of these with SCH but not in isolated hypothyroxinaemia. SCH and isolated hypothyroxinaemia are both associated with neuro-intellectual impairment of the child, but there is no evidence that maternal levothyroxine therapy improves this outcome. Targeted antenatal screening for thyroid function will miss a substantial percentage of women with thyroid dysfunction. In children SCH (serum TSH concentration >5.5-10 mU/l) normalizes in >70% and persists in the majority of the remaining patients over the subsequent 5 years, but rarely worsens. There is a lack of studies examining the impact of SCH on the neuropsychological development of children under the age of 3 years. In older children, the evidence for an association between SCH and impaired neuropsychological development is inconsistent. Good quality studies examining the effect of treatment of SCH in children are lacking. PMID:25114871

  5. Association of Graves’ disease and Graves’ ophthalmopathy with the polymorphisms in promoter and exon 1 of cytotoxic T lymphocyte associated antigen-4 gene

    PubMed Central

    Zhang, Qin; Yang, Yun-mei; Lv, Xue-ying

    2006-01-01

    Objective: To investigate the association of Graves’ disease and Graves’ ophthalmopathy with the C/T transition polymorphism at position ?318 of promoter and the A/G transition polymorphism at position 49 of exon 1 within cytotoxic T lymphocyte associated antigen-4 (CTLA-4) gene. Methods: Thirty-three patients with ophthalmopathy of Graves’ disease, fifty-six Graves’ patients without ophthalmopathy and sixty normal subjects as control were involved in the present case-control study. The polymorphisms were evaluated by polymerase chain reaction fragment length polymorphism (PCR-RFLP). Comparisons were made of gene frequencies and allele frequencies between the groups. Results: The gene frequencies of CT and allele frequencies of T were much higher in Graves’ patients with ophthalmopathy than that in the group without ophthalmopathy (P=0.020, P=0.019). The gene frequencies of GG and allele frequencies of G in patients with Graves’ disease were significantly increased as compared with control group (P=0.008, P=0.007). The data suggest that smokers with Graves’ disease seemed to be more predisposed to ophthalmopathy than non-smokers (P=0.018). Conclusion: Our results suggest that an allele of T at position ?318 of promoter is associated with genetic susceptibility to Graves’ ophthalmopathy while an allele of G at position 49 of exon 1 is associated with genetic susceptibility to Graves’ disease instead. Smoking is believed to be a major risk factor for ophthalmopathy. PMID:17048303

  6. Affinity of Mindscape and Landscape in Tao Qian and Emerson

    E-print Network

    Cheung, KK

    2015-01-01

    In American Transcendentalism: A Study Of Emerson, Thoreau,Emerson, Tao Qian, solitude, pastoral, Taoism, Transcendentalismand Emerson bespeaks a deeper ethic (whether grounded in Taoism or Transcendentalism)

  7. Digital Data From the Taos West Aeromagnetic Survey in Taos County, New Mexico

    USGS Publications Warehouse

    Bankey, Viki; Grauch, V.J.S.; Drenth, B.J.; EDCON-PRJ Inc.

    2007-01-01

    This report contains digital data, image files, and text files describing data formats and survey procedures for aeromagnetic data collected during a survey covering the southwestern portion of Taos County west of the Town of Taos, New Mexico, in October, 2006. Several derivative products from these data are also presented as grids and images, including reduced-to-pole data and data continued to a reference surface. Images are presented in various formats and are intended to be used as input to geographic information systems, standard graphics software, or map plotting packages.

  8. An excess of dietary iodine accelerates the development of a thyroid-associated lymphoid tissue in autoimmune prone BB rats.

    PubMed

    Mooij, P; de Wit, H J; Drexhage, H A

    1993-11-01

    Previous studies have shown that dietary iodine enhances the severity and incidence of focal thyroiditis in autoimmune BB rats and OS chickens. However, which lymphoid cells are involved in the development of the iodine-induced focal thyroiditis and what the consequences are for the anticolloid antibody production have not been studied in detail. We therefore performed a study in which 3-week-old female BB rats were kept on either an enriched iodine diet (EID; iodine intake, 100 micrograms iodine/day) or a normal iodine diet (NID; iodine intake, 7 micrograms iodine/day) for a period of 18 weeks. The development of the focal thyroiditis was immunohistologically studied. Immunohistological data were compared to the thyroid hormone status and anti-colloid antibody production. Our data confirm that a high dietary iodine intake results in an accelerated development of the focal lymphoid cell infiltrates in the thyroid of the BB rat. After 12-18 weeks of an EID 50% of the BB rats developed these infiltrates. Our data additionally show that: (a) the process starts with increases in the number of infiltrating MHC class II-positive dendritic cells and a clustering of these cells with T cells, B cells, and some macrophages and (b) the focal infiltrates are highly organized and consist of central B cell follicle-like structures surrounded by rims and areas of T cells. The architecture of the focal thyroiditis is hence very similar to mucosa-associated lymphoid tissue and secondary lymphoid organs (spleen and lymph node). Only minor signs of thyrocyte destruction were observed. We therefore consider the term "thyroiditis" as inappropriate and prefer the term "thyroid-associated lymphoid tissue." Since the thyroiditis component was small, it is also not surprising that the BB rats on the EID remained euthyroid. The presence of the thyroid-associated lymphoid tissue in the BB rats was positively correlated to the presence of anti-colloid antibody in the serum of the BB rats. We speculate that the dietary iodine might have direct effects on cells of the immune system or on cells forming the microenvironment of lymphoid tissue (reticulum cells). A role for highly iodinated thyroglobulin in the accelerated development of thyroid-associated lymphoid tissue is also possible. PMID:8403556

  9. Transcaruncular Medial Wall Orbital Decompression: An Effective Approach for Patients with Unilateral Graves Ophthalmopathy

    PubMed Central

    Hill, Robert H.; Czyz, Craig N.; Bersani, Thomas A.

    2012-01-01

    Purpose. To evaluate the reduction in proptosis, incidence of postoperative diplopia, and postoperative globe symmetry after transcaruncular medial wall decompression in patients with unilateral Graves ophthalmopathy. Methods. Retrospective review of 16 consecutive patients who underwent unilateral transcaruncular medial wall orbital decompression from 1995 to 2007. The diagnosis of Graves ophthalmopathy was based on history and clinical findings including proptosis, lagophthalmos, lid retraction, motility restriction, and systemic thyroid dysfunction. Results. The mean reduction in proptosis was 2.3?mm. The mean difference in exophthalmometry preoperatively between the two eyes in each patient was 3.1?mm whereas postoperatively the mean difference was 1.1?mm (P = 0.0002). Eleven of 16 patients (69%) had 1?mm or less of asymmetry postoperatively. There was no statistically significant difference in the incidence of diplopia pre and postoperatively (P = 1.0). Conclusions. Medial wall orbital decompression is a safe and practical surgical approach for patients with unilateral Graves orbitopathy. The procedure carries a low risk of morbidity and yields anatomic retrusion of the globe that is comparable to other more invasive methods and may yield more symmetric postoperative results. PMID:22654589

  10. Protracted Hypofractionated Radiotherapy for Graves' Ophthalmopathy: A Pilot Study of Clinical and Radiologic Response

    SciTech Connect

    Casimiro de Deus Cardoso, Cejana; Giordani, Adelmo Jose [Department of Clinical and Experimental Oncology, Division of Radiotherapy, Federal University of Sao Paulo, Sao Paulo, SP (Brazil); Borri Wolosker, Angela Maria [Department of Radiology, Federal University of Sao Paulo, Sao Paulo, SP (Brazil); Souhami, Luis [Department of Radiotherapy, McGill University Heath Centre, Montreal, Quebec (Canada); Gois Manso, Paulo [Department of Ophthalmology, Federal University of Sao Paulo, Sao Paulo, SP (Brazil); Souza Dias, Rodrigo; Comodo Segreto, Helena Regina [Department of Clinical and Experimental Oncology, Division of Radiotherapy, Federal University of Sao Paulo, Sao Paulo, SP (Brazil); Araujo Segreto, Roberto, E-mail: segreto.dmed@epm.br [Department of Clinical and Experimental Oncology, Division of Radiotherapy, Federal University of Sao Paulo, Sao Paulo, SP (Brazil)

    2012-03-01

    Purpose: To evaluate the clinical and radiologic response of patients with Graves' ophthalmopathy given low-dose orbital radiotherapy (RT) with a protracted fractionation. Methods and Materials: Eighteen patients (36 orbits) received orbital RT with a total dose of 10 Gy, fractionated in 1 Gy once a week over 10 weeks. Of these, 9 patients received steroid therapy as well. Patients were evaluated clinically and radiologically at 6 months after treatment. Clinical response assessment was carried out using three criteria: by physical examination, by a modified clinical activity score, and by a verbal questionnaire considering the 10 most common signs and symptoms of the disease. Radiologic response was assessed by magnetic resonance imaging. Results: Improvement in ocular pain, palpebral edema, visual acuity, and ocular motility was observed in all patients. Significant decrease in symptoms such as tearing (p < 0.001) diplopia (p = 0.008), conjunctival hyperemia (p = 0.002), and ocular grittiness (p = 0.031) also occurred. Magnetic resonance imaging showed decrease in ocular muscle thickness and in the intensity of the T2 sequence signal in the majority of patients. Treatments were well tolerated, and to date no complications from treatment have been observed. There was no statistical difference in clinical and radiologic response between patients receiving RT alone and those receiving RT plus steroid therapy. Conclusion: RT delivered in at a low dose and in a protracted scheme should be considered as a useful therapeutic option for patients with Graves' ophthalmopathy.

  11. TRUTH AND ACTION OSMOSIS (THE TAO COMPUTATION MODEL)

    E-print Network

    Vasconcelos, Vasco Thudichum

    TRUTH AND ACTION OSMOSIS (THE TAO COMPUTATION MODEL) ANT â?? ONIO PORTO, VASCO T. VASCONCELOS by the database. Commands always execute and as an e#ect may change the database. We thus have the osmosis

  12. Application of digital infrared thermal imaging in determining inflammatory state and follow-up effect of methylprednisolone pulse therapy in patients with Graves’ ophthalmopathy

    Microsoft Academic Search

    Tien-Chun Chang; Yung-Lien Hsiao; Shu-Lang Liao

    2008-01-01

    Background  Inflammation can cause a local increase in temperature. Digital infrared thermal imaging (DITI) has been used to monitor the\\u000a temperature distribution of human skin. Graves’ ophthalmopathy (GO) is an autoimmune disease, and patients are treated with\\u000a immunosuppressive agents if the ophthalmopathy is at an inflammatory state. The aim of the present study was to elucidate\\u000a the feasibility of DITI in

  13. Thyroid-stimulating immunoglobulins as measured in a reporter bioassay are not detected in patients with Hashimoto’s thyroiditis and ophthalmopathy or isolated upper eyelid retraction

    PubMed Central

    Wall, Jack R; Lahooti, Hooshang; El Kochairi, Ilhem; Lytton, Simon D; Champion, Bernard

    2014-01-01

    Although ophthalmopathy is mainly associated with Graves’ hyperthyroidism, milder eye changes are also found in about 25% of patients with Hashimoto’s thyroiditis (HT). The recent finding of negative thyrotropin receptor (TSHR) antibodies, as measured in the Thyretain™ thyroid-stimulating immunoglobulin (TSI) reporter bioassay, in patients with euthyroid Graves’ disease raises the possibility that TSHR antibodies are not the cause of ophthalmopathy in all situations. Here, we have tested serum from patients with HT with and without ophthalmopathy or isolated upper eyelid retraction (UER) for TSHR antibodies, using the TSI reporter bioassay and collagen XIII as a marker of autoimmunity against the orbital fibroblast. Study groups were 23 patients with HT with ophthalmopathy, isolated UER, or both eye features and 17 patients without eye signs. Thyretain™ TSI results were expressed as a percentage of the sample-to-reference ratio, with a positive test being taken as a sample-to-reference ratio of more than 140%. Serum collagen XIII antibodies were measured in standard enzyme-linked immunosorbent assay. TSI tests were positive in 22% of patients with HT with no eye signs but in no patient with eye signs. In contrast, TSI tests were positive in 94% of patients with Graves’ ophthalmopathy. Tests were negative in all normal subjects tested. Collagen XIII antibodies were detected in 83% of patients with ophthalmopathy, UER, or both eye features, but in only 30% of patients with no eye signs. Our findings suggest that TSHR antibodies do not play a major role in the pathogenesis of ophthalmopathy or isolated UER in patients with HT. Moreover, the role of TSHR antibodies in the development of ophthalmopathy in patients with Graves’ disease remains to be proven. In contrast, collagen XIII antibodies appear to be a good marker of eye disease in patients with HT. PMID:25336908

  14. Thyroid-stimulating immunoglobulins as measured in a reporter bioassay are not detected in patients with Hashimoto's thyroiditis and ophthalmopathy or isolated upper eyelid retraction.

    PubMed

    Wall, Jack R; Lahooti, Hooshang; El Kochairi, Ilhem; Lytton, Simon D; Champion, Bernard

    2014-01-01

    Although ophthalmopathy is mainly associated with Graves' hyperthyroidism, milder eye changes are also found in about 25% of patients with Hashimoto's thyroiditis (HT). The recent finding of negative thyrotropin receptor (TSHR) antibodies, as measured in the Thyretain™ thyroid-stimulating immunoglobulin (TSI) reporter bioassay, in patients with euthyroid Graves' disease raises the possibility that TSHR antibodies are not the cause of ophthalmopathy in all situations. Here, we have tested serum from patients with HT with and without ophthalmopathy or isolated upper eyelid retraction (UER) for TSHR antibodies, using the TSI reporter bioassay and collagen XIII as a marker of autoimmunity against the orbital fibroblast. Study groups were 23 patients with HT with ophthalmopathy, isolated UER, or both eye features and 17 patients without eye signs. Thyretain™ TSI results were expressed as a percentage of the sample-to-reference ratio, with a positive test being taken as a sample-to-reference ratio of more than 140%. Serum collagen XIII antibodies were measured in standard enzyme-linked immunosorbent assay. TSI tests were positive in 22% of patients with HT with no eye signs but in no patient with eye signs. In contrast, TSI tests were positive in 94% of patients with Graves' ophthalmopathy. Tests were negative in all normal subjects tested. Collagen XIII antibodies were detected in 83% of patients with ophthalmopathy, UER, or both eye features, but in only 30% of patients with no eye signs. Our findings suggest that TSHR antibodies do not play a major role in the pathogenesis of ophthalmopathy or isolated UER in patients with HT. Moreover, the role of TSHR antibodies in the development of ophthalmopathy in patients with Graves' disease remains to be proven. In contrast, collagen XIII antibodies appear to be a good marker of eye disease in patients with HT. PMID:25336908

  15. 77 FR 36994 - Questa Ranger District, Carson National Forest; Taos County, NM; Taos Ski Valley's 2010 Master...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-20

    ...proposal to authorize several (Phase 1) projects included in...are expected in July 2012. Change in Responsible Official: In addition, this notice changes the official responsible...Taos Ski Valley MDP--Phase 1 Projects, 208 Cruz...

  16. Results of diplopia and strabismus in patients with severe thyroid ophthalmopathy after orbital decompression

    PubMed Central

    Roncevic, Radmilo; Savkovic, Zorica; Roncevic, Dusan

    2014-01-01

    Purpose: It has been frequently stated that the orbital decompression, in patients with thyroid ophthalmopathy, does not usually improve extraocular muscles function and that after the operation there is often a deterioration of these functions. The purpose of this article is evaluation of extraocular muscles function after applying personal method of 3 wall orbital decompression. Materials And Methods: Retrospective review of case records of 119 patients with severe thyroid ophthalmopathy seen and treated by the author between December 1986 and December 2010. All patents underwent 3 wall orbital decompression combined with removal of the periorbital, intraorbital and retrobulbar fat. Correction of coexistent eyelid retraction and deformities were also performed. Results: Comparison of preoperative and postoperative results was conducted in 65 patients three months after 3 wall decompression. All patients showed a significant reduction of exophthalmos [5-11 mm, 7.2 mm on average], reduction of intraocular pressure, marked improvement in ocular muscle function as well as considerable reduction in or disappearance of subjective symptoms. There were no cases of subsequent impairment of ocular motility. Strabismus surgery was performed in 6 patients with residual diplopia. There was an improvement in vision in 68% patients who had impaired vision before the operation. Less evident relapse of exophthalmos was recorded in 3 cases only and only one patient required unilateral reoperation. Conclusion: It can be concluded that this method of orbital decompression is logical, based on an understanding of the pathology, has less complication rates, is relatively easy to perform, gives very good functional and aesthetic long term results and allows rapid recovery. PMID:24178400

  17. Prevalence of Graves’ ophthalmopathy in patients with Graves’ disease presenting to a referral centre in north India

    PubMed Central

    Reddy, Sagili Vijaya Bhaskar; Jain, Anu; Yadav, Subhash B.; Sharma, Kumudini; Bhatia, Eesh

    2014-01-01

    Background & objectives: The prevalence of Graves’ ophthalmopathy (GO) varies widely in different ethnic groups. Indians have been reported to have a lower prevalence of Graves’ ophthalmopathy as compared to Caucasians of European origin, but data are sparse and inconclusive. We studied the prevalence, clinical features and association of GO in Indian patients with Graves’ disease attending a referral centre in north India. Methods: A prospective study was conducted on 235 consecutive newly referred north Indian patients with Graves’ disease presenting to a tertiary care centre in north India. All patients underwent a comprehensive ophthalmological examination as per the European Group on Graves’ Orbitopathy (EUGOGO) recommendations. Results: GO was diagnosed in 65 patients (prevalence 28%; 95% confidence interval 22-33%). The prevalence was similar in males (28%) and females (27%). It was mild in 83 per cent, moderate-severe in 15 per cent and sight-threatening in only 2 per cent of cases. Ophthalmopathy was clinically active in only two (3%) cases. Upper eyelid retraction was the most common manifestation (83%), followed by exophthalmos (75%). Extra-ocular muscle involvement (5%) and optic nerve dysfunction (2%) were uncommon. The risk of GO was 3.9- fold (95% confidence interval 1.1-13.6) higher in smokers compared to non-smokers. However, severity of disease in smokers was similar to non-smokers. On multivariate logistic regression analysis, GO was associated only with high thyrotropin receptor antibody titres and current smoking. Interpretation & conclusions: Among north Indian patients with GD studied at a referral center, the prevalence of GO was similar to Caucasians of European descent, but clinically active and severe ophthalmopathy was uncommon. More studies are needed to confirm these findings. PMID:24604044

  18. T. Arbogast, Zhen Tao, and Hailong Xiao, Multiscale mortar mixed methods for heterogeneous elliptic prob-

    E-print Network

    Arbogast, Todd

    T. Arbogast, Zhen Tao, and Hailong Xiao, Multiscale mortar mixed methods for heterogeneous elliptic, Zhen Tao, and Hailong Xiao Abstract. Consider solving a second order elliptic problem when the elliptic Number DE-SC0001114. c 0000 (copyright holder) 1 #12;2 TODD ARBOGAST, ZHEN TAO, AND HAILONG XIAO where

  19. Comparison of TRMM rainfall retrievals with rain gauge data from the TAO/TRITON buoy array

    E-print Network

    Comparison of TRMM rainfall retrievals with rain gauge data from the TAO/TRITON buoy array Kenneth on the NOAA TAO/ TRITON buoy array in the tropical Pacific. The buoy rain gauges have an advantage over most. Phillips, and G. R. North, Comparison of TRMM rainfall retrievals with rain gauge data from the TAO/TRITON

  20. Automated differential photometry of TAOS data: preliminary analysis

    NASA Astrophysics Data System (ADS)

    Ricci, D.; Sprimont, P.-G.; Ayala, C.; Ramón-Fox, F. G.; Michel, R.; Navarro, S.; Wang, S.-Y.; Zhang, Z.-W.; Lehner, M. J.; Nicastro, L.; Reyes-Ruiz, M.

    2014-12-01

    A preliminary data analysis of the stellar light curves obtained by the robotic telescopes of the TAOS project is presented. We selected a data run relative to one of the stellar fields observed by three of the four TAOS telescopes, and we investigate the common trend and the correlation between the light curves. We propose two ways to remove these trends and show the preliminary results. A project aimed at flagging interesting behaviors, such as stellar variability, and to set up an automated follow-up with the San Pedro Mártir Facilities is on the way.

  1. Digital Aeromagnetic Data and Derivative Products from a Helicopter Survey over the Town of Taos and Surrounding Areas, Taos County, New Mexico

    USGS Publications Warehouse

    Bankey, Viki; Grauch, V.J.S.; Fugro Airborne Surveys Corporation

    2004-01-01

    This report contains digital data, image files, and text files describing data formats and survey procedures for aeromagnetic data collected during a helicopter geophysical survey in northern New Mexico during October 2003. The survey covers the Town of Taos, Taos Pueblo, and surrounding communities in Taos County. Several derivative products from these data are also presented, including reduced-to-pole, horizontal gradient magnitude, and downward continued grids and images.

  2. Langmuir-Blodgettry of Nanocrystals and ANDREA R. TAO,

    E-print Network

    Huang, Jiaxing

    Langmuir-Blodgettry of Nanocrystals and Nanowires ANDREA R. TAO, JIAXING HUANG, AND PEIDONG YANG or optical display. Langmuir-Blodgett (LB) assembly is a good candidate for arranging vast numbers, we present the Langmuir-Blodgett technique as a low-cost method for the massively parallel

  3. On Anti-Corruption Privacy Preserving Publication Yufei Tao 1

    E-print Network

    Zhang, Donghui

    , Donghui Zhang 2 1 Department of Computer Science and Engineering, Chinese University of Hong Kong Sha TinOn Anti-Corruption Privacy Preserving Publication Yufei Tao 1 , Xiaokui Xiao 1 , Jiexing Li 1, New Territories, Hong Kong {taoyf, xkxiao, jxli}@cse.cuhk.edu.hk 2 College of Computer and Information

  4. COMPRESSIVE IMAGE FUSION Tao Wan Nishan Canagarajah Alin Achim

    E-print Network

    COMPRESSIVE IMAGE FUSION Tao Wan Nishan Canagarajah Alin Achim Department of Electrical their performance on CS reconstruction. We then propose a new image fusion algorithm in the compressive domain by using an improved sampling pattern. There are few studies regarding the applicability of CS to image

  5. Discrimination of airborne material particles from light scattering (TAOS) patterns

    NASA Astrophysics Data System (ADS)

    Crosta, Giovanni F.; Pan, Yong-Le; Videen, Gorden; Aptowicz, Kevin B.; Chang, Richard K.

    2013-05-01

    Two-dimensional angle-resolved optical scattering (TAOS) is an experimental method which collects the intensity pattern of monochromatic light scattered by a single, micron-sized airborne particle. In general, the interpretation of these patterns and the retrieval of the particle refractive index, shape or size alone, are difficult problems. The solution proposed herewith relies on a learning machine (LM): rather than identifying airborne particles from their scattering patterns, TAOS patterns themselves are classified. The LM consists of two interacting modules: a feature extraction module and a linear classifier. Feature extraction relies on spectrum enhancement, which includes the discrete cosine Fourier transform and non-linear operations. Linear classification relies on multivariate statistical analysis. Interaction enables supervised training of the LM. The application described in this article aims at discriminating the TAOS patterns of single bacterial spores (Bacillus subtilis) from patterns of atmospheric aerosol and diesel soot particles. The latter are known to interfere with the detection of bacterial spores. Classification has been applied to a data set with more than 3000 TAOS patterns from various materials. Some classification experiments are described, where the size of training sets has been varied as well as many other parameters which control the classifier. By assuming all training and recognition patterns to come from the respective reference materials only, the most satisfactory classification result corresponds to ? 20% false negatives from Bacillus subtilis particles and <= 11% false positives from environmental and diesel particles.

  6. Modelling Electrical Car Diffusion Based on Agent Tao Zhang, 3

    E-print Network

    Aickelin, Uwe

    Modelling Electrical Car Diffusion Based on Agent 1 Lei Yu, ,2 Tao Zhang, 3 Siebers Peer-Ola, 4 to include things like car parking charges, price of electrical car, energy awareness and word of mouth parking rates and other incentives on the uptake of electrical cars. The goal of this case study

  7. 53. Photocopy of the original conception of Tao House drawn ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    53. Photocopy of the original conception of Tao House drawn by architect Frederick L. Confer and inscribed by Mrs. O'Neill to the builder, Lloyd C. Simpson. Dated 1937. - Eugene O'Neill House, Kuss Road, Danville, Contra Costa County, CA

  8. Music Data Mining: An Introduction Tao Li and Lei Li

    E-print Network

    Li, Tao

    Music Data Mining: An Introduction Tao Li and Lei Li October 17, 2010 #12;2 #12;Contents 1 Introduction 5 1.1 Music Data Sources . . . . . . . . . . . . . . . . . . . . . . . . . 5 1.2 An Introduction and Algorithms . . . . . . . . . . . . . 11 1.3 Music Data Mining

  9. American Thyroid Association

    MedlinePLUS

    ... Clinical Thyroidology – Highlighted Article From Clinical Thyroidology: Radioactive Iodine Treatment for Women with Thyroid Cancer Is Associated ... and with Decreased Fertility in Older Women – Radioactive iodine treatment for thyroid cancer has been linked to ...

  10. 75 FR 71414 - Questa Ranger District, Carson National Forest; Taos County, NM; Taos Ski Valley's 2010 Master...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-23

    ...proposing to authorize several (Phase I) projects included in the...2010 Master Development Plan--Phase 1 Projects. DATES: Comments...Forest, Taos Ski Valley MDP--Phase 1 Projects, 208 Cruz Alta Road...of the existing permit area. 3. Quality alternative...

  11. Prof. Andrea Tao (left), Dr. Fariba Farhoo, DARPA YFA Program Manager Andrea Tao, assistant professor of NanoEngineering, was recently awarded a 2014 Young Faculty Award

    E-print Network

    Dey, Sujit

    Prof. Andrea Tao (left), Dr. Fariba Farhoo, DARPA YFA Program Manager Andrea Tao, assistant Advanced Research Projects Agency (DARPA) for her research project, "Plasmonic Nanoprobes for Neuronal Monitoring." According to DARPA, "The objective of the DARPA Young Faculty Award (YFA) program is to identify

  12. THE TAOS PROJECT: RESULTS FROM SEVEN YEARS OF SURVEY DATA

    SciTech Connect

    Zhang, Z.-W.; Lehner, M. J.; Wang, J.-H.; Wen, C.-Y.; Wang, S.-Y.; King, S.-K.; Cook, K. H.; Lee, T. [Institute of Astronomy and Astrophysics, Academia Sinica. 11F of Astronomy-Mathematics Building, National Taiwan University. No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan (China); Granados, A. P. [Instituto de Astronomia, Universidad Nacional Autonoma de Mexico, Apdo. Postal 106, Ensenada, Baja California 22800 (Mexico); Alcock, C.; Protopapas, P. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Axelrod, T. [Steward Observatory, 933 North Cherry Avenue, Room No. 204, Tucson AZ 85721 (United States); Bianco, F. B. [Center for Cosmology and Particle Physics, New York University, 4 Washington Place, New York, NY 10003 (United States); Byun, Y.-I. [Department of Astronomy and University Observatory, Yonsei University, 134 Shinchon, Seoul 120-749 (Korea, Republic of); Chen, W. P. [Institute of Astronomy, National Central University, No. 300, Jhongda Road, Jhongli City, Taoyuan County 320, Taiwan (China); Coehlo, N. K. [Department of Statistics, University of California Berkeley, 367 Evans Hall, Berkeley, CA 94720 (United States); De Pater, I. [Department of Astronomy, University of California Berkeley, 601 Campbell Hall, Berkeley, CA 94720 (United States); Kim, D.-W. [Max Planck Institute for Astronomy, Koenigstuhl 17, D-69117 Heidelberg (Germany); Lissauer, J. J. [Space Science and Astrobiology Division 245-3, NASA Ames Research Center, Moffett Field, CA 94035 (United States); Marshall, S. L., E-mail: zwzhang@asiaa.sinica.edu.tw [Kavli Institute for Particle Astrophysics and Cosmology, 2575 Sand Hill Road, MS 29, Menlo Park, CA 94025 (United States); and others

    2013-07-01

    The Taiwanese-American Occultation Survey (TAOS) aims to detect serendipitous occultations of stars by small ({approx}1 km diameter) objects in the Kuiper Belt and beyond. Such events are very rare (<10{sup -3} events per star per year) and short in duration ({approx}200 ms), so many stars must be monitored at a high readout cadence. TAOS monitors typically {approx}500 stars simultaneously at a 5 Hz readout cadence with four telescopes located at Lulin Observatory in central Taiwan. In this paper, we report the results of the search for small Kuiper Belt objects (KBOs) in seven years of data. No occultation events were found, resulting in a 95% c.l. upper limit on the slope of the faint end of the KBO size distribution of q = 3.34-3.82, depending on the surface density at the break in the size distribution at a diameter of about 90 km.

  13. Status of the Transneptunian Automated Occultation Survey (TAOS II)

    NASA Astrophysics Data System (ADS)

    Lehner, Matthew J.; Wang, Shiang-Yu; Alcock, Charles A.; Cook, Kem H.; Furesz, Gabor; Geary, John C.; Hiriart, David; Ho, Paul T.; Lee, William H.; Melsheimer, Frank; Norton, Timothy; Reyes-Ruiz, Mauricio; Richer, Michael; Szentgyorgyi, Andrew; Yen, Wei-Ling; Zhang, Zhi-Wei

    2014-07-01

    The Transneptunian Automated Occultation Survey (TAOS II) will aim to detect occultations of stars by small (~1 km diameter) objects in the Kuiper Belt and beyond. Such events are very rare (< 10-3 events per star per year) and short in duration (~200 ms), so many stars must be monitored at a high readout cadence. TAOS II will operate three 1.3 meter telescopes at the Observatorio Astronómico Nacional at San Pedro Mártir in Baja California, México. With a 2.3 square degree field of view and a high speed camera comprising CMOS imagers, the survey will monitor 10,000 stars simultaneously with all three telescopes at a readout cadence of 20 Hz. Construction of the site began in the fall of 2013.

  14. First Results From The Taiwanese-American Occultation Survey (TAOS)

    E-print Network

    Z. -W. Zhang; F. B. Bianco; M. J. Lehner; N. K. Coehlo; J. -H. Wang; S. Mondal; C. Alcock; T. Axelrod; Y. -I. Byun; W. -P. Chen; K. H. Cook; R. Dave; I. de Pater; R. Porrata; D. -W. Kim; S. -K. King; T. Lee; H. -C. Lin; J. J. Lissauer; S. L. Marshall; P. Protopapas; J. A. Rice; M. E. Schwamb; S. -Y. Wang; C. -Y. Wen

    2008-08-14

    Results from the first two years of data from the Taiwanese-American Occultation Survey (TAOS) are presented. Stars have been monitored photometrically at 4 Hz or 5 Hz to search for occultations by small (~3 km) Kuiper Belt Objects (KBOs). No statistically significant events were found, allowing us to present an upper bound to the size distribution of KBOs with diameters 0.5 km < D < 28 km.

  15. First Results From The Taiwanese-American Occultation Survey (TAOS)

    SciTech Connect

    Zhang, Z; Bianco, F B; Lehner, M J; Coehlo, N K; Wang, J; Mondal, S; Alcock, C; Axelrod, T; Byun, Y; Chen, W P; Cook, K H; Dave, R; de Pater, I; Porrata, R; Kim, D; King, S; Lee, T; Lin, H; Lissauer, J J; Marshall, S L; Protopapas, P; Rice, J A; Schwamb, M E; Wang, S; Wen, C

    2008-08-22

    Results from the first two years of data from the Taiwanese-American Occultation Survey (TAOS) are presented. Stars have been monitored photometrically at 4 Hz or 5 Hz to search for occultations by small ({approx}3 km) Kuiper Belt Objects (KBOs). No statistically significant events were found, allowing us to present an upper bound to the size distribution of KBOs with diameters 0.5 km < D < 28 km.

  16. Postoperative Drift in Patients with Thyroid Ophthalmopathy Undergoing Unilateral Inferior Rectus Muscle Recession

    PubMed Central

    Peragallo, Jason H.; Velez, Federico G.; Demer, Joseph L.; Pineles, Stacy L.

    2013-01-01

    Background Extraocular muscles of patients with thyroid ophthalmopathy (TO) may respond differently to strabismus surgery than those of other strabismic patients. This study reports postoperative alignment changes in patients with TO compared with patients with non-restrictive strabismus following unilateral inferior rectus muscle recession (IRR). Methods We reviewed records of patients with and without TO who underwent unilateral IRR. Group A had adjustable muscle sutures, while Group B had permanent or semi-adjustable sutures. Controls were patients undergoing adjustable unilateral IRR for other indications. Results Mean preoperative hypotropias were 17 ± 9, 21 ± 7, and 11 ± 4 PD for groups A (n = 13), B (n = 14), and controls (n = 19), respectively. Postoperative day one (POD1) measurements after adjustment were 1.2 ± 2.5, 3.7 ± 4.9, and 0.3 ± 2.4 PD, respectively, representing overall undercorrections in all cases (the preoperative deviation was given a positive (+) value and overcorrections were deemed negative (?) deviations). Dose response from linear regression analysis of thyroid patients compared with control patients for IRR was 3.26 PD/mm (SE 0.18) vs 2.38 PD/mm (SE 0.18) (p = 0.001). Mean final measurements were ?0.7 ± 5.6 (overcorrection), 2.7 ± 5.7, and 1.7 ± 5.7 PD of hypotropia, respectively. Final overcorrections occurred in 23%, 14%, and 16% of patients, for adjustables, permanent sutures, and control subjects, respectively. Drifts from POD1 measurements after adjustment to final measurements were ?1.9 ± 4.3, ?1.0 ± ;4.6, and 1.4 ± 5.9 PD respectively (p = 0.05 for comparison between Group A and controls). Conclusions TO patients with adjustable sutures drift toward postoperative overcorrection. PMID:23477773

  17. Molecular cloning and characterization of genes for antibodies generated by orbital tissue-infiltrating B-cells in Graves` ophthalmopathy

    SciTech Connect

    Jaume, J.C.; Portolano, S.; Prummel, M.F.; McLachlan, S.M.; Rapoport, B. [Univ. of California, San Francisco, CA (United States)] [Univ. of California, San Francisco, CA (United States)

    1994-02-01

    Graves` ophthalmopathy is a distressing autoimmune disease of unknown etiology. Analysis of the genes for antibodies secreted by orbital tissue-infiltrating plasma cells might provide insight into the pathogenesis of this disease. The authors, therefore, constructed an immunoglobulin heavy (H) chain and an immunoglobulin k light (L) chain cDNA library from the orbital tissue of a patient with active Graves` ophthalmopathy. Analysis of 15 H (IgG1) and 15 L (k) chains revealed a restricted spectrum of variable region genes. Fourteen of 15 variable k genes were about 94% homologous to the closest known germline gene, KL012. Thirteen of 15 H chain genes were 91% and 90% homologous to the closest germline genes, DP10 and hv1263, respectively. Remarkably, these germline genes also code for other autoantibodies to striated muscle (KL012) and thyroid peridase (KL012 and hv1263). These studies raise the possibility that particular germline genes may be associated with autoimmunity in humans. Further, the present study opens the way to identifying ocular autoantigens that may be the target of an humoral immune response. 29 refs., 4 figs., 1 tab.

  18. Taos State Office Building, Taos, New Mexico: solar-energy-system performance evaluation, June 1981March 1982

    Microsoft Academic Search

    1982-01-01

    The Taos State Office Building is a single-story New Mexico office building which incorporates an integrated passive solar heating and daylighting system. The system is designed to provide 70% of the heating load. Solar energy enters the building via 11 rows of clerestory windows, south-facing windows, and east and west window scoops. Collected solar energy is stored in 14,080 gallons

  19. 77 FR 38375 - Notice of Availability of the Final Environmental Impact Statement (FEIS) for the Taos Regional...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ...and the New Mexico Department of Transportation regarding adverse effects on the Taos Pueblo World Heritage Site and other traditional cultural properties within the National Register Eligible Historic District associated with the Taos...

  20. 75 FR 66345 - Proposed Amendment of Class E Airspace; Taos, NM

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-28

    ...at Taos, NM. Decommissioning of the Ski non-directional beacon (NDB) at Taos...regulatory, aeronautical, economic, environmental, and energy-related aspects of the...necessary due to the decommissioning of the Ski NDB and the cancellation of the NDB...

  1. In 2006, Terence Tao was awarded the Fields Medal (the mathematical equivalent of the Nobel Prize).

    E-print Network

    Vakil, Ravi

    In 2006, Terence Tao was awarded the Fields Medal (the mathematical equivalent of the Nobel Prize). Among his other awards are the Bôcher Prize, the SASTRA Ramanujan Prize, the Clay Research Award, the Nemmers Prize, and, in 2010, he shared the P�lya Prize. Terence TaoJames and Carol Collins Chair

  2. Towards Research on Goal Reasoning with the TAO Sandbox Bryan Auslander1

    E-print Network

    Gupta, Kalyan Moy

    Towards Research on Goal Reasoning with the TAO Sandbox Bryan Auslander1 , Matthew Molineaux2 of intelligent agent research. The Tactical Action Officer (TAO) Sandbox, developed at the University of Southern Sandbox in our artificial intelligence research, where we are currently focusing on algorithms

  3. Audiomagnetotelluric data, Taos Plateau Volcanic Field, New Mexico

    USGS Publications Warehouse

    Ailes, Chad E.; Rodriguez, Brian D.

    2011-01-01

    The U.S. Geological Survey is conducting a series of multidisciplinary studies of the San Luis Basin as part of the Geologic framework of the Rio Grande Basins project. Detailed geologic mapping, high-resolution airborne magnetic surveys, gravity surveys, audiomagnetotelluric surveys, and hydrologic and lithologic data are being used to better understand the aquifers. This report describes a regional east-west audiomagnetotelluric sounding profile acquired in late July 2009 across the Taos Plateau Volcanic Field. No interpretation of the data is included.

  4. Pliocene Volcanic Evolution of the Taos Plateau, New Mexico

    NASA Astrophysics Data System (ADS)

    Cosca, M. A.; Thompson, R. A.; Turner, K. J.; Lee, J. P.

    2012-12-01

    New geologic mapping (1:24k-1:50k scale) and high precision 40Ar/39Ar geochronology of volcanic rocks from the Taos Plateau in northern New Mexico reveals nearly 4 million years of predominantly mafic (basalt to andesite) volcanism associated with the Pliocene to Quaternary Rio Grande rift. A nearly continuous record of volcanism is recorded from ~5 to ~1 Ma with two major pulses of magmatism observed at ~4.5 Ma and ~3 Ma reflecting eruption from more than 50 mapped centers and an unresolved number of centers buried by intercalated rift volcanics and sedimentary basin fill. Volcanism, both outflow thickness and vent locations, is strongly controlled by the same north to northwest trending fault systems defining the Rio Grande rift graben. However, active loci of volcanism can be linked to sub-basins within the broader graben structure. Large composite volcanoes ranging in composition from basaltic andesite to andesite, such as Guadeloupe Mountain (~4.5-5 Ma), Ute Mountain (~3.9 Ma), and San Antonio Mountain (~3 Ma) formed over time intervals of about 300 ka during the most voluminous stages of activity. Similar time intervals are recorded in each of three Servilleta basalt flow packages (lower (~4.5 Ma), middle (~4 Ma), and upper (~3.5 Ma)) observed at the Rio Grande gorge just north of Taos that first began erupting at ~ 4.7 Ma. Distinctive reddish paleosols between each Servilleta flow package represent time intervals between eruptions of ~0.5 Ma. Late stage volcanic activity (< 3 Ma) is recorded as small volume Servilleta basalt volcanoes and numerous small basalt to basaltic andesite cinder cones and associated lavas flows. Mesita Cone, dated at ~ 1 Ma and offset by middle Pleistocene faulting, represents the youngest volcanic activity within the Taos plateau segment of the Rio Grande Rift. The Pliocene to Quaternary volcanic rocks of the Taos Plateau are locally underlain by 1) Precambrian crystalline granite basement, 2) Oligocene calc-alkaline volcanic and associated intrusive rocks of the southern Rocky Mountain volcanic field, 3) a mafic to intermediate composition Miocene volcanic platform in the northern part of the plateau, or 4) Miocene to Quaternary basin-fill deposits in actively subsiding extensional sub-basins of the eastern plateau. The stratigraphic relationship of this Pliocene volcanism to the earlier igneous activity, mapped faults, and erosional unconformities establishes temporal constraints on regional extension prior to Pliocene rifting. Preliminary 40Ar/39Ar results and integrated mapping support an interpretation of contemporaneous rift sub-basin development and Pliocene volcanism as the primary manifestation of continental rifting vs. regional extension in northern New Mexico.

  5. The incidence of ophthalmopathy after radioiodine therapy for Graves` disease: Prognostic factors and the role of methimazole

    SciTech Connect

    Kung, A.W.C. [Univ. of Hong Kong, Pokfulam (Hong Kong)] [Univ. of Hong Kong, Pokfulam (Hong Kong); Cheng, A. [Queen Mary Hospital, Pokfulam (Hong Kong)] [Queen Mary Hospital, Pokfulam (Hong Kong)

    1994-08-01

    Radioactive iodine-131 (RAI) has been reported to be associated with a high incidence of development or exacerbation of Graves` ophthalmopathy (GO). This is thought to be associated with a surge of autoantibodies after RAI therapy. The role of methimazole (MMI), which possesses immunomodulatory action, in the prevention of GO was explored by studying 114 patients with Graves` disease. They were assigned randomly to receive either RAI alone or adjunctive antithyroid drugs, which consisted of MMI and L-T{sub 4} as a block-replacement therapy for 12 months and were followed for 2 yr. Thirty-five patients (30.7%) had GO at presentation. Twenty-one (18%) patients developed new GO, and six had worsening of preexisting GO. The development of hypothyroidism (P < 0.01) and an elevation of TSH (P < 0.05) were associated with increased risk of development or exacerbation of GO. The chance of development or exacerbation of GO is higher in those with no ophthalmopathy than in those with preexisting GO at presentation (P = 0.002). The incidence of development or exacerbation of GO was similar in the two treatment groups (RAI, 22.8%; adjunctive antithyroid drugs, 23.7%; P = NS). MMI was able to suppress the surge of TSH receptor antibody (TRAB) after RAI, but a surge in TRAB was not of prognostic significance for the development of GO after RAI. Patients who developed or had exacerbation of GO actually had lower TRAB at presentation (P = 0.02). The authors conclude that hypothyroidism with elevated TSH is an important adverse factor for the development or exacerbation of GO, and MMI was unable to prevent the development or exacerbation of GO after RAI. 35 refs., 4 tabs.

  6. Drosophila tao Controls Mushroom Body Development and Ethanol-Stimulated Behavior through par-1

    PubMed Central

    King, Ian; Tsai, Linus T.-Y.; Pflanz, Ralf; Voigt, Aaron; Lee, Seongsoo; Jäckle, Herbert; Lu, Bingwei; Heberlein, Ulrike

    2011-01-01

    In both mammalian and insect models of ethanol-induced behavior, low doses of ethanol stimulate locomotion. However, the mechanisms of the stimulant effects of ethanol on the CNS are mostly unknown. We have identified tao, encoding a serine-threonine kinase of the Ste20 family, as a gene necessary for ethanol-induced locomotor hyperactivity in Drosophila. Mutations in tao also affect behavioral responses to cocaine and nicotine, making flies resistant to the effects of both drugs. We show that tao function is required during the development of the adult nervous system and that tao mutations cause defects in the development of central brain structures, including the mushroom body. Silencing of a subset of mushroom body neurons is sufficient to reduce ethanol-induced hyperactivity, revealing the mushroom body as an important locus mediating the stimulant effects of ethanol. We also show that mutations in par-1 suppress both the mushroom body morphology and behavioral phenotypes of tao mutations and that the phosphorylation state of the microtubule-binding protein Tau can be altered by RNA interference knockdown of tao, suggesting that tao and par-1 act in a pathway to control microtubule dynamics during neural development. PMID:21248138

  7. Web-based tools for the analysis of TAOS data and much more

    NASA Astrophysics Data System (ADS)

    Ricci, D.; Sprimont, P.-G.; Ayala, C.; Ramón-Fox, F. G.; Michel, R.; Navarro, S.; Wang, S.-Y.; Zhang, Z.-W.; Lehner, M. J.; Nicastro, L.; Reyes-Ruiz, M.

    2014-12-01

    We suggest a new web-based approach for browsing and visualizing data produced by a network of telescopes, such as those of the ongoing TAOS and the forthcoming TAOS II projects. We propose a modern client-side technology and we present two examples based on two software packages developed for different kinds of server-side database approaches. In spite our examples are specific for the browsing of TAOS light curves, the software is coded in a way to be suitable for the use in several types of astronomical projects.

  8. Status of the Transneptunian Automated Occultation Survey (TAOS II)

    NASA Astrophysics Data System (ADS)

    Reyes-Ruiz, Mauricio

    2014-11-01

    TAOS II is a next generation occultation survey with the goal of measuring the size distribution of the small objects (diameters between 0.5 and 30 km) in the Kuiper Belt. The project is a collaboration between the Academia Sinica Institute of Astronomy and Astrophysics, the Universidad Nacional Autonoma de Mexico, and the Harvard-Smithsonian Center for Astrophysics, The survey will operate three 1.3 m telescopes at San Pedro Martir Observatory in Baja California, Mexico. Each telescope will be equipped with a custom camera comprising a focal plane array of CMOS imagers. Each camera will be capable of reading out image data from 10,000 stars at a cadence of 20 Hz. All telescopes will monitor the same set of stars simultaneously to search for coincident occultation events while minimizing the false positive rate. This poster describes the project and reports on the progress of the development of the survey infrastructure.

  9. 2013 European Thyroid Association Guidelines for Cervical Ultrasound Scan and Ultrasound-Guided Techniques in the Postoperative Management of Patients with Thyroid Cancer

    PubMed Central

    Leenhardt, L.; Erdogan, M.F.; Hegedus, L.; Mandel, S.J.; Paschke, R.; Rago, T.; Russ, G.

    2013-01-01

    Cervical ultrasound scanning (US) is considered a key examination, by all major thyroid and endocrine specialist societies for the postoperative follow-up of thyroid cancer patients to assess the risk of recurrence. Neck US imaging is readily available, non-invasive, relatively easy to perform, cost-effective, and can guide diagnostic and therapeutic procedures with low complication rates. Its main shortcoming is its operator-dependency. Because of the pivotal role of US in the care of thyroid cancer patients, the European Thyroid Association convened a panel of international experts to review technical aspects, indications, results, and limitations of cervical US in the initial staging and follow-up of thyroid cancer patients. The main aim is to establish guidelines for both a cervical US scanning protocol and US-guided diagnostic and therapeutic procedures in patients with thyroid cancer. This report presents (1) standardization of the US scanning procedure, techniques of US-guided fine-needle aspiration, and reporting of findings; (2) definition of criteria for classification of malignancy risk based on cervical US imaging characteristics of neck masses and lymph nodes; (3) indications for US-guided fine-needle aspiration and for biological in situ assessments; (4) proposal of an algorithm for the follow-up of thyroid cancer patients based on risk stratification following histopathological and cervical US findings, and (5) discussion of the potential use of US-guided localization and ablation techniques for locoregional thyroid metastases. PMID:24847448

  10. Prediction of thermal acoustic oscillations (TAOs) in the CLAES solid CO2/neon system

    NASA Technical Reports Server (NTRS)

    Spradley, I. E.; Yuan, S. W. K.

    1991-01-01

    Results are presented of a study initiated to investigate the possibility that the existence of thermal acoustic oscillations (TAOs) in the Cryogenic Limb Atmospheric Etalon Spectrometer (CLAES) neon plumbing system ground configuration could be the cause of higher-than-predicted heat rates measured during thermal ground testing. Tests were conducted between warm boundary temperatures ranging from 40 to 100 K, which simulated the actual test conditions of the CLAES CO2/neon system. TAOs were observed between 6 and 106 Torr, which agreed with the analytical predictions, and verified the possible existence of TAOs in the CLAES system during ground testing. The presence of TAOs was eventually confirmed in the CLAES system during a subsequent thermal test and were determined to have caused the higher heat rates measured during the prior thermal test.

  11. TAO1 kinase maintains chromosomal stability by facilitating proper congression of chromosomes.

    PubMed

    Shrestha, Roshan L; Tamura, Naoka; Fries, Anna; Levin, Nicolas; Clark, Joanna; Draviam, Viji M

    2014-06-01

    Chromosomal instability can arise from defects in chromosome-microtubule attachment. Using a variety of drug treatments, we show that TAO1 kinase is required for ensuring the normal congression of chromosomes. Depletion of TAO1 reduces the density of growing interphase and mitotic microtubules in human cells, showing TAO1's role in controlling microtubule dynamics. We demonstrate the aneugenic nature of chromosome-microtubule attachment defects in TAO1-depleted cells using an error-correction assay. Our model further strengthens the emerging paradigm that microtubule regulatory pathways are important for resolving erroneous kinetochore-microtubule attachments and maintaining the integrity of the genome, regardless of the spindle checkpoint status. PMID:24898139

  12. Growth hormone gene polymorphisms and growth performance traits in duroc, Landrace and Tao-Yuan Pigs

    Microsoft Academic Search

    Winston T. K. Cheng; C. H. Lee; C. M. Hung; T. J. Chang; C. M. Chen

    2000-01-01

    This study investigated the restriction fragment length polymorphism (RFLP) of the porcine growth hormone (pGH) gene in Duroc, Landrace, and Tao-Yuan pigs and its effects on growth performance and levels of plasma growth hormone in peripheral circulation. Genomic DNA extracted from 81 Tao-Yuan, 60 Landrace and 48 Duroc pigs were subjected to Southern blot hybridization with a pGH cDNA probe.

  13. TaO x -based resistive switching memories: prospective and challenges

    NASA Astrophysics Data System (ADS)

    Prakash, Amit; Jana, Debanjan; Maikap, Siddheswar

    2013-10-01

    Resistive switching memories (RRAMs) are attractive for replacement of conventional flash in the future. Although different switching materials have been reported; however, low-current operated devices (<100 ?A) are necessary for productive RRAM applications. Therefore, TaO x is one of the prospective switching materials because of two stable phases of TaO2 and Ta2O5, which can also control the stable low- and high-resistance states. Long program/erase endurance and data retention at high temperature under low-current operation are also reported in published literature. So far, bilayered TaO x with inert electrodes (Pt and/or Ir) or single layer TaO x with semi-reactive electrodes (W and Ti/W or Ta/Pt) is proposed for real RRAM applications. It is found that the memory characteristics at current compliance (CC) of 80 ?A is acceptable for real application; however, data are becoming worst at CC of 10 ?A. Therefore, it is very challenging to reduce the operation current (few microampere) of the RRAM devices. This study investigates the switching mode, mechanism, and performance of low-current operated TaO x -based devices as compared to other RRAM devices. This topical review will not only help for application of TaO x -based nanoscale RRAM devices but also encourage researcher to overcome the challenges in the future production.

  14. Growth of (Na, K, Li)(Nb, Ta)O 3 single crystals by solid state crystal growth

    Microsoft Academic Search

    John G. Fisher; Andreja Ben?an; Janez Bernard; Janez Holc; Marija Kosec; Sophie Vernay; Daniel Rytz

    2007-01-01

    A single crystal of (Na, K, Li)(Nb, Ta)O3 has been grown for the first time by the solid state crystal growth process. A seed crystal of ?001?-oriented KTaO3 was embedded in a matrix of (Na, K, Li)(Nb, Ta)O3 powder, which was then densified by hot-pressing. During annealing of the hot-pressed sample, a single crystal of (Na, K, Li)(Nb, Ta)O3 of

  15. Multiple Bytes Differential Fault Analysis on CLEFIA Xin-jie ZHAO, Tao WANG, Jing-zhe GAO

    E-print Network

    Multiple Bytes Differential Fault Analysis on CLEFIA Xin-jie ZHAO, Tao WANG, Jing-zhe GAO of the world have made many security analyses on it. In the previous DFA attacks on CLEFIA, Chen et al.[14 to #12;2 Xin-jie ZHAO, Tao WANG, Jing-zhe GAO recover 4 bytes of the rth round key, after attacking

  16. A genomic point mutation in the extracellular domain of the thyrotropin receptor in patients with Graves` ophthalmopathy

    SciTech Connect

    Bahn, R.S.; Dutton, C.M.; Heufelder, A.E.; Sarkar, G. [Mayo Clinic/Foundation, Rochester, MN (United States)] [Mayo Clinic/Foundation, Rochester, MN (United States); [Ludwig-Maximilians-Universitat, Munich (Germany)

    1994-02-01

    Orbital and pretibial fibroblasts are targets of autoimmune attack in Graves` ophthalmopathy (GO) and pretibial dermopathy (PTD). The fibroblast autoantigen involved in these peripheral manifestations of Graves` disease and the reason for the association of GO and PTD with hyperthyroidism are unknown. RNA encoding the full-length extracellular domain of the TSH receptor has been demonstrated in orbital and dermal fibroblasts from patients with GO and normal subjects, suggesting a possible antigenic link between fibroblasts and thyrocytes. RNA was isolated from cultured orbital, pretibial, and abdominal fibroblasts obtained from patients with severe GO (n = 22) and normal subjects (n = 5). RNA was reverse transcribed, and the resulting cDNA was amplified by the polymerase chain reaction, using primers spanning overlapping regions of the entire extracellular domain of the TSH receptor. Nucleotide sequence analysis showed an A for C substitution in the first position of codon 52 in 2 of the patients, both of whom had GO, PTD, and acropachy. Genomic DNA isolated from the 2 affected patients, and not from an additional 12 normal subjects, revealed the codon 52 mutation by direct sequencing and AciI restriction enzyme digestions. In conclusion, the authors have demonstrated the presence of a genomic point mutation, leading to a threonine for proline amino acid shift in the predicted peptide, in the extracellular domain of the TSH receptor in two patients with severe GO, PTD, acropachy, and high thyroid-stimulating immunoglobulin levels. RNA encoding this mutant product was demonstrated in the fibroblasts of these patients. They suggest that the TSH receptor may be an important fibroblast autoantigen in GO and PTD, and that this mutant form of the receptor may have unique immunogenic properties. 28 refs., 3 figs., 2 tabs.

  17. Association of TLR7 and TSHR copy number variation with Graves’ disease and Graves’ ophthalmopathy in Chinese population in Taiwan

    PubMed Central

    2014-01-01

    Background Graves’ disease (GD) and Graves’ ophthalmopathy (GO) are autoimmune disorders, which might be influenced by genetic factors. Copy number variation (CNV) is an important source of genomic diversity in humans, and influences disease susceptibility. This study investigated the association between CNV in the TSHR and TLR7 genes and the development of GD and GO in a Chinese population in Taiwan. Methods For this case-control study, sample from 196 healthy controls and 484 GD patients, including 203 patients with GO were studied. CNV was detected by real-time polymerase chain reaction (PCR) using TaqMan™ probes and the relative copy number (CN) was estimated by using the comparative Ct method. Results The differences in the distribution of TSHR CNV in healthy controls and GD patients were statistically significant (p value?=?0.01). However, the difference in the distribution of TSHR CNV in the control group and the GO group was not statistically significant (p value?=?0.06). For TLR7 CNV, the results were not significantly different when we compared the distribution in healthy controls and GD patients and in healthy controls and GO patients (p values for Fisher’s exact test were 0.13 and 0.09, respectively). However, a lower than normal CNV for TLR7 (CNV?

  18. Searching Similar Segments over Textual Event Sequences Liang Tang Tao Li Shu-Ching Chen

    E-print Network

    Li, Tao

    Searching Similar Segments over Textual Event Sequences Liang Tang Tao Li Shu-Ching Chen School of Computer Science Florida International University Miami, Florida, 33199, U.S.A {ltang002,taoli,chens}@cs.fiu.edu Shunzhi Zhu School of Computer & Information Engineering Xiamen University of Technology Xiamen, P

  19. ECvisual: A Visualization Tool for Elliptic Curve Based Jun Tao, Jun Ma

    E-print Network

    Shene, Ching-Kuang

    on cryptography (e.g., [3, 10, 14, 15]). We could not find visualization tools for the elliptic curve basedECvisual: A Visualization Tool for Elliptic Curve Based Ciphers Jun Tao, Jun Ma Department teach elliptic curve based ciphers. This tool permits the user to visualize elliptic curves over

  20. Towards Intelligent Music Information Retrieval Tao Li and Mitsunori Ogihara, Member, IEEE

    E-print Network

    Li, Tao

    access to a large amount of on-line music data, including music sound signals, lyrics, biographies1 Towards Intelligent Music Information Retrieval Tao Li and Mitsunori Ogihara, Member, IEEE Abstract-- Efficient and intelligent music information retrieval is a very important topic of the 21st

  1. CSC2522 Course Project Michael Tao 6.1 Rendering Wet Sand

    E-print Network

    Toronto, University of

    CSC2522 Course Project Michael Tao 6.1 Rendering Wet Sand 6.1.1 Goals The primary goal of this project was to implement a method for rendering sand as a wet porous medium with water flowing into it from within PBRT. The final result was a video of sand being wetted by water particles flowing through

  2. Guidelines for Financial Forecasting with Neural Networks JingTao YAO

    E-print Network

    Yao, JingTao

    ], foreign exchange rates forecasting [15, 24], option prices [25], advertising and sales volumes [13Guidelines for Financial Forecasting with Neural Networks JingTao YAO Dept of Information Systems@comp.nus.edu.sg Abstract Neural networks are good at classification, forecasting and recognition. They are also good

  3. The TAOS Project Stellar Variability II. Detection of 15 Variable Stars

    SciTech Connect

    Mondal, S; Lin, C C; Zhang, Z W; Alcock, C; Axelrod, T; Bianco, F B; Byun, Y I; Coehlo, N K; Cook, K H; Dave, R; Kim, D W; King, S K; Lee, T; Lehner, M J; Lin, H C; Marshall, S L; Protopapas, P; Rice, J A; Schwamb, M E; Wang, J H; Wang, S Y; Wen, C Y

    2010-01-28

    The Taiwanese-American Occultation Survey (TAOS) project has collected more than a billion photometric measurements since 2005 January. These sky survey data - covering timescales from a fraction of a second to a few hundred days - are a useful source to study stellar variability. A total of 167 star fields, mostly along the ecliptic plane, have been selected for photometric monitoring with the TAOS telescopes. This paper presents our initial analysis of a search for periodic variable stars from the time-series TAOS data on one particular TAOS field, No. 151 (RA = 17{sup h} 30{sup m} 6.67{sup s}, Dec = 27 degrees, 17 minutes, 30 seconds, J2000), which had been observed over 47 epochs in 2005. A total of 81 candidate variables are identified in the 3 square degree field, with magnitudes in the range 8 < R < 16. On the basis of the periodicity and shape of the lightcurves, 32 variables, 18 of which were previously unknown, are classified as RR Lyrae, Cepheid, {delta} Scuti, SX Phonencis, semi-regular and eclipsing binaries.

  4. Web Search Engines: Practice and Experience Tao Yang, University of California at Santa Barbara

    E-print Network

    Yang, Tao

    Web Search Engines: Practice and Experience Tao Yang, University of California at Santa Barbara previously accessed URLs. Consequently, the service from a search engine becomes indispensable for users to navigate around the Web in an effective manner. General web search engines provide the most popular way

  5. A MORE EFFICIENT APPROXIMATION SCHEME FOR TREE LUSHENG WANG, TAO JIANG, AND DAN GUSFIELD

    E-print Network

    Wang, Lusheng

    . For example, most methods for phylogeny reconstruction based on sequence data assume a given multiple sequence- FG03-90ER60999. 283 #12;284 LUSHENG WANG, TAO JIANG, AND DAN GUSFIELD in a phylogeny reconstruction experiment) which has created the molecular (DNA, RNA, or amino acid)

  6. Histology Image Classification using Supervised Classification and Multimodal Tao Meng, Lin Lin, Mei-Ling Shyu

    E-print Network

    Chen, Shu-Ching

    Histology Image Classification using Supervised Classification and Multimodal Fusion Tao Meng, Lin for biomedical images. Among such efforts, histology image classification is one of the most important areas due Subspace Projection Modeling (C- RSPM) supervised classification model for general histology image

  7. Giving Meanings to WWW Images Heng Tao Shen Beng Chin Ooi Kian-Lee Tan

    E-print Network

    Ooi, Beng Chin

    Giving Meanings to WWW Images Heng Tao Shen Beng Chin Ooi Kian-Lee Tan Department of Computer Science National University of Singapore 3 Science Drive 2, Singapore 117543 ABSTRACT Images a rich source of image collection from which users can query. Interestingly, the semantics

  8. The cultural and ecological impacts of aboriginal tourism: a case study on Taiwan's Tao tribe.

    PubMed

    Liu, Tzu-Ming; Lu, Dau-Jye

    2014-01-01

    We show that tourism activities severely impact the ecology of Orchid Island, its natural resources, and the culture of the Tao tribe. For example, highway widening, in response to the increased traffic volumes caused by tourism, required many Pandanus trees to be cut and removed, which has placed the coconut crabs in danger of extinction. To promote eco-tourism, observation trips to observe Elegant Scops owls and Birdwing butterflies have taken place, which has affected the breeding of these two protected species. The Elegant Scops owls- and Birdwing butterflies-related tourism activities also break the "evil spirits" taboo of the Tao people and have caused the disappearance of the specifications for using traditional natural resources, causing natural ecosystems to face the threat of excessive use. In addition to promoting and advocating aboriginal tourism of the Tao people on Orchid Island, the Taiwanese government should help the Tao people to develop a management model that combines traditional regulations and tourism activities. PMID:25089246

  9. Turtle Geometry in Computer Graphics and Computer Aided Design Ron Goldman, Scott Schaefer, Tao Ju

    E-print Network

    Schaefer, Scott

    Turtle Geometry in Computer Graphics and Computer Aided Design Ron Goldman, Scott Schaefer, Tao Ju@cs.rice.edu, sschaefe@rice.edu, jutao@cs.rice.edu Abstract: LOGO is a programming language incorporating turtle graphics, relaxation methods and subdivision schemes from elementary notions in turtle geometry and turtle programming

  10. Quantify Music Artist Similarity Based on Style and Mood Bo Shao, Tao Li

    E-print Network

    Li, Tao

    Quantify Music Artist Similarity Based on Style and Mood Bo Shao, Tao Li School of Computer Science of Computer Science University of Miami Coral Gables, FL 33134 ogihara@cs.miami.edu ABSTRACT Music artist. The similarity varies sig- nificantly due to different artistic aspects considered and most importantly

  11. The epidemiologic characteristics and clinical course of ophthalmopathy associated with autoimmune thyroid disease in Olmsted County, Minnesota.

    PubMed Central

    Bartley, G B

    1994-01-01

    Among incident cases of GO in Olmsted County, Minnesota: GO affected females six times more frequently than males (86% versus 14% of cases, respectively). The age-adjusted incidence rate was 16 cases per 100,000 population per year for females and 2.9 cases per 100,000 population for males. The peak incidence rates were bimodal, occurring in the age groups 40 to 44 years and 60 to 64 years in females and 45 to 49 years and 65 to 69 years in males. Among patients with GO, approximately 90% had Graves' hyperthyroidism, 1% had primary hypothyroidism, 3% had Hashimoto's thyroiditis, and 5% were euthyroid. Eyelid retraction was the most common ophthalmic feature of autoimmune thyroid disease, being present either unilaterally or bilaterally in more than 90% of patients at some point in their clinical course. Exophthalmos of one or both eyes affected approximately 60% of patients, restrictive extraocular myopathy was apparent in about 40% of patients, and optic nerve dysfunction occurred in either one or both eyes in 6% of patients with autoimmune thyroid disease. Only 5% of patients had the complete constellation of classic findings: eyelid retraction, exophthalmos, optic nerve dysfunction, extraocular muscle involvement, and hyperthyroidism. Upper eyelid retraction, either unilateral or bilateral, was documented in approximately 75% of patients at the time of diagnosis of GO. Lid lag also was a frequent early sign, being present either unilaterally or bilaterally in 50% of patients at the initial examination. At the time of diagnosis of GO, the most frequent ocular symptom was pain or discomfort, which affected 30% of patients. Some degree of diplopia was noted by approximately 17% of patients, lacrimation or photophobia was present in about 15% to 20% of patients, and 7.5% of patients complained of blurred vision. Decreased vision attributable to optic neuropathy was present in less than 2% of eyes at the time of diagnosis of GO. Thyroid dermopathy and acropachy accompanied GO in approximately 4% and 1% of patients, respectively. Myasthenia gravis occurred in less than 1% of patients. Superior limbic keratoconjunctivitis was documented in less than 4% of patients. The median age at the time of diagnosis of GO was 43 years (range, 8 to 88). Among patients with hyperthyroidism, 61% developed ophthalmopathy within 1 year of the onset of thyrotoxicosis. Symptoms and signs for which statistically significant changes occurred between the initial and final examinations included lacrimation, pain or ocular discomfort, photophobia, eyelid retraction, lid lag, eyelid fullness, conjunctival injection, chemosis, and exophthalmos.(ABSTRACT TRUNCATED AT 400 WORDS) Images FIGURE 1 FIGURE 2 FIGURE 3 PMID:7886878

  12. 77 FR 31036 - Notice of Availability of the Record of Decision for the Taos Resource Management Plan...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-24

    ...DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLNMF02000 L16100000.DT0000 LXSS026G0000...of Decision for the Taos Resource Management Plan/Environmental Impact Statement AGENCY: Bureau of Land Management, Interior. ACTION: Notice of...

  13. Two Early Gamma-ray Bursts Optical Afterglow Detections with TAOS Telescopes--GRB 071010B and GRB 071112C

    SciTech Connect

    Huang, K. Y.; Wang, S. Y. [Institute of Astronomy and Astrophysics, Academia Sinica, P.O. Box 23-141, Taipei 106, Taiwan (China); Urata, Y. [Dept. of Physics, Saitama University, Shimookubo, Saitama 338-8570 Japan (Japan); Institute of Astronomy and Astrophysics, Academia Sinica, P.O. Box 23-141, Taipei 106, Taiwan (China)

    2009-05-25

    We present on two early detections of GRB afterglows with the Taiwanese-American Occltation Sruvey (TAOS) telescopes. The robotic TAOS system has been devised so that the routine Kuiper Belt Object (KBO) survey is interrupted when a GRB alert is triggered. Our first detection, GRB 071010B was detected by TAOS 62 s after the burst and showed a weak early brightening during the observations. No significant correction with the prompt gamma-ray emission indicated that our optical emission detected is afterglow emission. The second detection of TAOS, GRB 071112C was detected 96 s after the burst, also showed a possible initial raising then followed a steep decay in the R-band light curve.

  14. Curanderismo in Taos County, New Mexico--a possible case of anthropological romanticism?

    PubMed

    Scheper-Hughes, N; Stewart, D

    1983-12-01

    Interviews with 25 Spanish-Americans of Taos County, New Mexico, indicate that time and acculturation have greatly eroded the belief in and practice of curanderismo, the traditional folk medical system of the Southwest. Curanderismo in northern New Mexico today has moved from being a primary and important source of medical care to one used alternatively and very occasionally in cases of pediatric disorders, chronic illnesses and pain, and for those maladies still classified according to the traditional folk beliefs. PMID:6666104

  15. Search for small trans-Neptunian objects by the TAOS project

    Microsoft Academic Search

    W. P. Chen; C. Alcock; T. Axelrod; F. B. Bianco; Y. I. Byun; Y. H. Chang; K. H. Cook; R. Dave; J. Giammarco; D. W. Kim; S. K. King; T. Lee; M. Lehner; C. C. Lin; H. C. Lin; J. J. Lissauer; S. Marshall; N. Meinshausen; S. Mondal; I. de Pater; R. Porrata; J. Rice; M. E. Schwamb; A. Wang; S. Y. Wang; C. Y. Wen; Z. W. Zhang

    2007-01-01

    The Taiwan-America Occultation Survey (TAOS) aims to conduct a census of small icy bodies in the outer reach of the Solar System, by means of stellar occultation. An array of 4 small (aperture 0.5 m), wide-field (f\\/1.9) telescopes have been installed at Lulin Observatory in Taiwan to monitor some one thousand stars simultaneously for such rare occultation events. The occurrence

  16. Curanderismo in Taos County, New Mexico—A Possible Case of Anthropological Romanticism?

    PubMed Central

    Scheper-Hughes, Nancy; Stewart, David

    1983-01-01

    Interviews with 25 Spanish-Americans of Taos County, New Mexico, indicate that time and acculturation have greatly eroded the belief in and practice of curanderismo, the traditional folk medical system of the Southwest. Curanderismo in northern New Mexico today has moved from being a primary and important source of medical care to one used alternatively and very occasionally in cases of pediatric disorders, chronic illnesses and pain, and for those maladies still classified according to the traditional folk beliefs. PMID:6666104

  17. Competition between inhibitors of the trypanosome alternative oxidase (TAO) and reduced coenzyme Q9.

    PubMed

    Pollakis, G; Grady, R W; Dieck, H A; Clarkson, A B

    1995-10-12

    The trypanosome alternative oxidase (TAO) is an attractive target for chemotherapy for the diseases caused by African trypanosomes because there is no equivalent enzyme in mammalian hosts. Many inhibitors of this enzyme have been described, but there have been no data on the mechanism of inhibition. In the present study, reduced 2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone (decyl-CoQ-H2) was used as a substitute for the natural substrate CoQ9-H2 to allow direct measurements of the TAO in crude mitochondrial preparations from Trypanosoma brucei brucei. A Km value of 3.8 microM was obtained for this substrate. The following five compounds that have alkyl side chains from 1 to 4 carbons and belong to three classes of inhibitors showed a competitive inhibition pattern with respect to decyl-CoQ-H: p-methoxybenzhydroxamic acid, p-ethoxybenzhydroxamic acid,p-n-butyloxybenzhydroxamic acid, methyl 3,4-dihydroxybenzoate and N-n-butyl-3,4-dihydroxybenzamide. The following four compounds belonging to the same chemical classes but having alkyl side chains from 10 to 12 carbons showed uncompetitive inhibition patterns: p-n-dodecyloxybenzhydroxamic acid, n-decyl 3,4-dihydroxybenzoate, n-dodecyl 3,4-dihydroxybenzoate, and N-n-decyl-3,4-dihydroxybenzamide. Clearly, the first group of inhibitors compete with CoQ-H2 for the active site of the TAO. We propose that the uncompetitive patterns produced by the second group of inhibitors are due to the greater lipophilicity of these compounds and the resulting change in the interaction of the inhibitors and the membrane containing the TAO, thus affecting the local concentration of the inhibitors at the active site. PMID:7488235

  18. Radionuclide concentrations in soils and produce from Cochiti, Jemez, Taos, and San Ildefonso Pueblo Gardens

    SciTech Connect

    Fresquez, P.R.; Armstrong, D.R.; Salazar, J.G.

    1995-05-01

    Radionuclide ({sup 3}H, {sup 90}Sr, {sup 137}Cs, {sup 238}Pu, {sup 239}Pu, and total uranium) concentrations were determined in soils and produce collected from Cochiti, Jemez, Taos, and San Ildefonso Pueblo gardens. All radionuclides in soils from Pueblo areas were within or just above regional statistical (natural and/or worldwide fallout) reference levels. Similarily, the average levels of radionuclides in produce collected from Cochiti, Jemez, Taos, and San Ildefonso Pueblo gardens were not significantly different in produce collected from regional (background) locations. The effective (radiation) dose equivalent from consuming 352 lb of produce from Cochiti, Jemez, Taos, and San Ildefonso, after natural background has been subtracted, was 0.036 ({+-}0.016), 0.072 ({+-}0.051), 0.012 ({+-}0.027), and 0.110 ({+-}0.102) mrem/yr, respectively. The highest calculated dose, based on the mean + 2 std dev (95% confidence level), was 0.314 mrem/yr; this was <0.4% of the International Commission on Radiological Protection permissible dose limit for protecting members of the public.

  19. UPLC-QTOF-MS with chemical profiling approach for rapidly evaluating chemical consistency between traditional and dispensing granule decoctions of Tao-Hong-Si-Wu decoction

    PubMed Central

    2012-01-01

    Background In the present study, chemical consistency between traditional and dispensing granule decoctions of Tao-Hong-Si-Wu decoction was rapidly evaluated by UPLC-QTOF-MS coupled with the MarkerLynx software. Two different kinds of decoctions, namely traditional decoction: water extract of mixed six constituent herbs of Tao-Hong-Si-Wu decoction, and dispensing granules decoction: mixed water extract of each individual herbs of Tao-Hong-Si-Wu decoction, were prepared. Results Chemical difference was found between traditional and dispensing granule decoctions, and albiflorin, paeoniflorin, gallic acid, amygdalin, and hydroxysafflor yellow A were identified as the significantly changed components during decocting Tao-Hong-Si-Wu decoction. All the peaks of mass spectrum from Tao-Hong-Si-Wu decoction and each herb were extracted and integration by using QuanLynx™. And the optimized data was used for linear regression analysis. The contribution of each herb in Tao-Hong-Si-Wu decoction, and the optimal compatibility proportion of dispensing granule decoction were derived from the linear regression equation. Conclusions The optimal dosage proportionality of Tao-Hong-Si-Wu dispensing granule decoction was obtained as 2.5:0.2:1:0.5:0.6:0.1 (DG : CX : BS : SD : TR : HH), which guided better clinic application of Tao-Hong-Si-Wu decoction as dispensing granule decoctions usage, and it also provided some experimental data to reveal the compatibility rule of the relative TCM formulae. PMID:23176049

  20. Pueblos, Poets, and Painters: The Role of the Pueblo Indians in the Development of the Santa Fe-Taos Region as an American Cultural Center.

    ERIC Educational Resources Information Center

    Reeve, Kay A.

    1981-01-01

    Historically, the Pueblo Indians appealed to artists and writers' colonies in Santa Fe-Taos (New Mexico), inspiring a superficial art and, on a deeper level, inspiring a desire to explore and communicate the Pueblos' intrinsic values. The deeper appeal crucially influenced the establishment and continued productivity of the Santa Fe-Taos American…

  1. LANL:CPO: Los Alamos National Laboratory Impacts and Investments in Taos County LA-UR 11-02376 (2/13/13)

    E-print Network

    for elementary and middle-school students in Taos County to help prepare them for the academic year. Student Support: LANL Laces is a year-round Laboratory employee-giving program designed to purchase shoes County. Students and teachers from the Taos and Penasco School Districts participated in one or more

  2. Peroxisome proliferator-activated receptor-gamma gene expression in orbital adipose/connective tissues is increased during the active stage of Graves' ophthalmopathy.

    PubMed

    Mimura, Lídia Y; Villares, Sandra M F; Monteiro, Mário L R; Guazzelli, Isabel C; Bloise, Walter

    2003-09-01

    The mechanisms involved in the increase of orbital retro-ocular adipose tissue that occurs in Graves' ophthalmopathy (GO) are still unclear. In this condition, the orbital tissue shows glycosaminoglycans deposition produced by activated fibroblasts capable of undergoing adipocytic differentiation. Many genes are involved in adipogenic mechanisms including the transcription factor peroxisome proliferator-activated receptor-gamma (PPAR-gamma). We evaluated the level of expression of the PPAR-gamma gene in normal and GO orbital adipose/connective tissue specimens using a quantitative and sensitive reverse transcription (RT) competitive polymerase chain reaction (PCR) assay. Our results show that the expression of PPAR-gamma was significantly greater in adipose/connective tissue from patients in the active stage of GO than in controls (150.8 +/- 103.9 and 24.0 +/- 4.9 amol/micro g of total RNA respectively, p < 0.05), while there was no significant difference between patients with inactive GO (58.8 +/- 40.6 aM/microg total RNA) and controls. These results suggest that increased PPAR-gamma gene expression in the active stage of GO may be dependent on the inflammatory process in this disease. We speculate that the increased orbital fat tissue observed in GO may be a consequence of the anti-inflammatory PPAR-gamma action. PMID:14588098

  3. Search for small trans-Neptunian objects by the TAOS project

    NASA Astrophysics Data System (ADS)

    Chen, W. P.; Alcock, C.; Axelrod, T.; Bianco, F. B.; Byun, Y. I.; Chang, Y. H.; Cook, K. H.; Dave, R.; Giammarco, J.; Kim, D. W.; King, S. K.; Lee, T.; Lehner, M.; Lin, C. C.; Lin, H. C.; Lissauer, J. J.; Marshall, S.; Meinshausen, N.; Mondal, S.; de Pater, I.; Porrata, R.; Rice, J.; Schwamb, M. E.; Wang, A.; Wang, S. Y.; Wen, C. Y.; Zhang, Z. W.

    2007-05-01

    The Taiwan-America Occultation Survey (TAOS) aims to conduct a census of small icy bodies in the outer reach of the Solar System, by means of stellar occultation. An array of 4 small (aperture 0.5 m), wide-field (f/1.9) telescopes have been installed at Lulin Observatory in Taiwan to monitor some one thousand stars simultaneously for such rare occultation events. The occurrence rate of the events would provide constraints on the number and space distribution of the Kuiper-belt Objects (KBOs). As the building blocks of planets and moons, KBOs preserve the formation and early dynamical evolution history of the Solar System. The TAOS project is a collaboration of institutions in Taiwan (Academia Sinica and NCU), the USA (U. Pennsylvannia, Harvard-Smithsonian CfA, Lawrence Livermore National Lab, NASA/Ames, UC-Berkeley), and Korea (Yonsei U.) Because a typical occultation event by a KBO is expected to last for only a fraction of a second, fast photometry is necessary. A true occultation event is considered securely detected if the flux drop is seen in all telescopes. Photometry of a thousand stars, for which the data should be processed, analyzed, and correlated among all telescopes in real time, is a daunting task. Routine observations began in early 2005 and so far a few billion photometric measurements have been collected. Even though no KBO occultation event has been detected, a few certain models on the population of the KBOs can be ruled out already. We will present our special data acquisition and analysis schemes and our statistical results. A few test cases will be shown for which the TAOS system was used to detect stellar occultation events by known asteroids. In addition to the KBO science, the huge TAOS database, ~ some 100 GB per night, would be valuable in other, e.g., stellar variability, studies. Our robotic telescope systems are also responding to gamma-ray bursts. We will present a few examples of variable stars observed by

  4. Electrode-material dependent switching in TaO x memristors

    NASA Astrophysics Data System (ADS)

    Ge, Ning; Zhang, M.-X.; Zhang, Lu; Yang, J. Joshua; Li, Zhiyong; Williams, R. Stanley

    2014-10-01

    We have studied the effect of top electrode materials on the switching behavior of TaO x based memristors with an identical switching oxide layer and bottom electrode stack. We found that the virgin resistance, electroforming and switching performance depend heavily on the chemical property of the top electrode materials. In addition, the electrical properties of metal oxides formed with the top electrodes also contribute to the overall memristor performance, including the nonlinearity of the current–voltage relationship. These results provide insights into understanding of memristor behavior as well as approaches for device property engineering.

  5. Paleomagnetism and tectonic interpretations of the Taos Plateau volcanic field, Rio Grande rift, New Mexico

    NASA Technical Reports Server (NTRS)

    Brown, Laurie L.; Caffall, Nancy M.; Golombek, Matthew P.

    1993-01-01

    The tectonic response of the Taos Plateau volcanic field in the southern San Luis basin to late stage extensional environment of the Rio Grande rift was investigate using paleomagnetic techniques. Sixty-two sites (533 samples) of Pliocene volcanic units were collected covering four major rock types with ages of 4.7 to 1.8 Ma. Twenty-two of these sites were from stratigraphic sections of the lower, middle and upper Servilleta Basalt collected in the Rio Grande gorge at two locations 19 km apart. Flows from the lower and middle members in the southern gorge record reversed polarities, while those in Garapata Canyon are normal with an excursion event in the middle of the sequence. The uppermost flows of the upper member at both sites display normal directions. Although these sections correlate chemically, they seem to represent different magnetic time periods during the Gilbert Reversed-Polarity Chron. The data suggest the Taos Plateau volcanic field, showing no rotation and some flattening in the south and east, has acted as a stable buttress and has been downwarped by overriding of the southeastern end of the plateau by the Picuris Mountains, which make up the northern corner of the counter-clockwise rotating Espanola block.

  6. TAOS: Taiwan-American Occultation Survey of Comet-Sized Objects in the Kuiper Belt

    NASA Technical Reports Server (NTRS)

    Lissauer, Jack; DeVincenzi, Donald (Technical Monitor)

    1999-01-01

    Several dozen minor planets with radii greater than 100 km have been detected beyond Neptune using large telescopes. The TAOS project is to measure directly the number of these KBOs (Kuiper Belt Objects) down to the typical size of cometary nuclei (a few km) and out as far as approximately 100 AU from the Sun. Because of their large distance, small sizes and presumed low albedos, these target objects are extremely faint. Three 50 cm wide field robotic telescopes with 2048 x 2048 CCD cameras will be deployed along a 7 km east-west baseline in or near Jade Mountain National Park in Taiwan. They will monitor approximately 3000 stars for occultations by KBOs in a coincidence mode, so that the sequence and timing of the three separate blinkings can be used to distinguish real events from false alarms. Follow-up imaging observations using large telescopes will yield albedos and orbits for some of the larger objects detected by TAOS. A fourth telescope on a north-south spur to refine the size information on occulting GABON is also being contemplated.

  7. Kinetic Origin of Divergent Decompression Pathways in Silicon and Germanium Jian-Tao Wang,1,2,* Changfeng Chen,2

    E-print Network

    Wang, Wei Hua

    Kinetic Origin of Divergent Decompression Pathways in Silicon and Germanium Jian-Tao Wang,1, but upon decompression they turn into metastable BC8 Si and ST12 Ge phases, respectively, instead-rotation mechanism with a low kinetic barrier. Kinetics also play a central role in selecting the decompression

  8. Application of Wavelet Neural Networks to Lidar Signal De-noising Hai-Tao Fang 1, 2

    E-print Network

    Hefei Institute of Intelligent Machines

    monitoring, but the effective range is often limited by signal-to-noise ratio. The reason is that noisesApplication of Wavelet Neural Networks to Lidar Signal De-noising Hai-Tao Fang 1, 2 , De, 230026, China 2 fanght@iim.ac.cn dshuang@iim.ac.cn Abstract- The Lidar is an efficient tool for remote

  9. Cation exchange in a 3D perovskite-synthesis of Ni(0.5)TaO?.

    PubMed

    Amano Patino, Midori; Smith, Thomas; Zhang, Weiguo; Halasyamani, P Shiv; Hayward, Michael A

    2014-08-01

    Reaction of NiCl2 with NaTaO3 leads the formation of the perovskite phase Ni(0.5)TaO3, via a topochemical nickel-for-sodium cation exchange in which the framework of apex-linked TaO6 octahedra present in the parent phase is retained. Neutron powder diffraction data indicate Ni(0.5)TaO3 adopts a structure analogous to the paraelectric phase of LiTaO3, with triclinic P1 crystallographic symmetry. Although Ni(0.5)TaO3 has features which make it a good candidate phase for magnetoelectric multiferroic behavior, the phase remains paramagnetic in the temperature range 15 < T (K) < 300, and detailed crystallographic characterization and analysis of SHG activity indicate it retains a centrosymmetric structure down to the lowest temperatures measured (5 K). Topochemical cation exchange reactions of 3D perovskite oxides offer the opportunity to prepare a wide range of novel metastable phases in a rational manner with a high degree of synthetic control. PMID:25050865

  10. Retrofitting Unit Tests for Parameterized Unit Madhuri R. Marri, Suresh Thummalapenta, Tao Xie, Nikolai Tillmann, Jonathan de Halleux

    E-print Network

    Young, R. Michael

    possible important values for test data (such as argument values of methods invoked in unit testsRetrofitting Unit Tests for Parameterized Unit Testing Madhuri R. Marri, Suresh Thummalapenta, Tao}@ncsu.edu, {nikolait, jhalleux}@microsoft.com Abstract--Maintenance of software applications requires unit tests

  11. PHILOSOPHY (I-LI) VERSUS PHILOLOGY (K'AO-CHENG): THE JEN-HSIN TAO-HSIN DEBATE*

    E-print Network

    Elman, Benjamin

    of the Confucian Classics. In particular, we will focus on the famous jen-hsin Tao-hsin [the human mind in philosophic orientation transformed Confucian inquiry from a quest for moral perfection to a programmatic-ching since the Former Han dynasty (206 B.C.-A.D. 8), the Documents became a centerpiece of the Confucian

  12. TAO, Vol. 16, No. 3, 563-577, August 2005 Preliminary Results from Seismic Monitoring at the Tatun Volcanic

    E-print Network

    Lin, Cheng-Horng

    563 TAO, Vol. 16, No. 3, 563-577, August 2005 Preliminary Results from Seismic Monitoring Pu 2 , Chia Chi Hsu 3 , Yu Mei Lin 4 , Shuei Huei You 4 and Yuan Ping Huang4 (Manuscript received 6, Taiwan, ROC 2 Institute of Geophysics, National Central University, Chung-Li, Taiwan, ROC 3 Dept

  13. TUMS: Twitter-based User Modeling Service Ke Tao, Fabian Abel, Qi Gao, Geert-Jan Houben

    E-print Network

    Langendoen, Koen

    Information Systems, Delft University of Technology {k.tao,f.abel,q.gao,g.j.p.m.houben}@tudelft.nl Abstract the messages people post on Twitter. It features topic detection and entity extrac- tion for tweets and allows-adaptive systems suffer from cold-start and sparsity problems [2]. For example, when systems have to deal with new

  14. A characteristic optic disc appearance associated with myopia in subjects with Graves’ ophthalmopathy and in subjects with primary open-angle glaucoma

    PubMed Central

    Yamazaki, Sei; Inoue, Rishu; Tsuboi, Toshikazu; Kozaki, Ai; Inoue, Toshu; Inoue, Toyoko; Inoue, Yoichi

    2013-01-01

    Purpose To determine if qualitatively defining the appearance of optic disc change was a valid characteristic of myopia in subjects with Graves’ ophthalmopathy (GO) or primary open-angle glaucoma (POAG). Methods We defined typical tilt appearance as the simultaneous presence of the following: an elliptical optic disc, a crescent, unequal sharpness of the cupping margin (horizontally), and nasally displaced vessels in the optic cup. Ninety-two eyes from 92 subjects each with GO or with POAG and no severe complications were included in the study after matching for spherical refractive errors. Using our definition of tilt appearance, two independent observers subjectively judged optic disc photographs. One observer repeated judgments in 70 randomly selected eyes and judgment reproducibility was assessed using kappa statistics. Tilt ratio was used as a quantitative parameter. Results The numbers of eyes judged as having a typical tilt appearance in the GO group and in the POAG group were 25 (27.2%) and 39 (42.4%), respectively, by one observer (P = 0.0297), and 12 (13%) and 44 (47.8%), respectively, by another observer (P < 0.0001). Intra- and interobserver reproducibility of tilt judgment were very good (kappa = 0.93) and good (kappa = 0.65), respectively. Tilt ratio did not significantly differ between the two groups. Analytical results including background factors were essentially the same for the two observers: multivariate logistic regression for one observer’s judgment showed that the presence of the typical tilt appearance was associated with belonging to the glaucoma group (odds ratio [OR], 6.25; P = 0.0054), tilt ratio (OR per 0.01, 0.77; P < 0.0001), and spherical refractive error (OR per diopter, 0.80; P < 0.003). Conclusion The optic disc feature we designated as typical tilt was associated with myopia, and its frequency was higher in subjects with POAG compared to those with GO. PMID:23326183

  15. Paleomagnetism and Tectonic Interpretations of the Taos Plateau Volcanic Field, Rio Grande Rift, New Mexico

    NASA Technical Reports Server (NTRS)

    Brown, Laurie L.; Caffall, Nancy M.; Golombek, Matthew P.

    1993-01-01

    The tectonic response of the Taos Plateau volcanic field in the southern San Luis basin to the late stage extensional environment of the Rio Grande rift was investigated using paleomagnetic techniques. Sixty-two sites (533 samples) of Pliocene volcanic units were collected covering four major rock types with ages of 4.7 to 1.8 Ma. Twenty-two of these sites were from stratigraphic sections of the lower, middle and upper Servilleta Basalt collected in the Rio Grande gorge at two locations 19 km apart. Flows from the lower and middle members in the southern gorge record reversed polarities, while those in Garapata Canyon are normal with an excursion event in the middle of the sequence. The uppermost flows of the upper member at both sites display normal directions. Although these sections correlate chemically, they seem to represent different magnetic time periods during the Gilbert Reversed-Polarity Chiron. Alternating field demagnetization, aided by principal component analysis, yields 55 sites with stable directions representing both normal and reversed polarities, and five sites indicating transitional fields. Mean direction of the normal and inverted reversed sites is I=49.3 deg. and D=356.7 deg. (alpha(sub 95)=3.6 deg). Angular dispersion of the virtual geomagnetic poles is 16.3 deg, which is consistent with paleosecular variation model G, fit to data from the past 5 m.y. Comparison with the expected direction indicates no azimuthal rotation of the Taos Plateau volcanic field; inclination flattening for the southern part of the plateau is 8.3 deg +/- 5.3 deg. Previous paleomagnelic data indicate 10 deg- 15 deg counterclockwise rotation of die Espanola block to the south over the past 5 m.y. The data suggest the Taos Plateau volcanic field, showing no rotation and some flattening in the south and east, has acted as a stable buttress and has been downwarped by overriding of the southeastern end of the plateau by the Picuris Mountains, which make up the northern corner of the counterclockwise rotating Espanola block.

  16. Thyrotropin Regulates IL-6 Expression in CD34+ Fibrocytes: Clear Delineation of Its cAMP-Independent Actions

    PubMed Central

    Raychaudhuri, Nupur; Fernando, Roshini; Smith, Terry J.

    2013-01-01

    IL-6 plays diverse roles in normal and disease-associated immunity such as that associated with Graves’ disease (GD). In that syndrome, the orbit undergoes remodeling during a process known as thyroid-associated ophthalmopathy (TAO). Recently, CD34+ fibrocytes were found to infiltrate the orbit in TAO where they transition into CD34+ orbital fibroblasts. Surprisingly, fibrocytes display high levels of functional thyrotropin receptor (TSHR), the central antigen in GD. We report here that TSH and the pathogenic anti-TSHR antibodies that drive hyperthyroidism in GD induce IL-6 expression in fibrocytes and orbital fibroblasts. Unlike TSHR signaling in thyroid epithelium, that occurring in fibrocytes is completely independent of adenylate cyclase activation and cAMP generation. Instead TSH activates PDK1 and both AKT/PKB and PKC pathways. Expression and use of PKC?II switches to that of PKCµ as fibrocytes transition to TAO orbital fibroblasts. This shift is imposed by CD34? orbital fibroblasts but reverts when CD34+ fibroblasts are isolated. The up-regulation of IL-6 by TSH results from coordinately enhanced IL-6 gene promoter activity and increased IL-6 mRNA stability. TSH-dependent IL-6 expression requires activity at both CREB (?213 to ?208 nt) and NF-?B (–78 to ?62 nt) binding sites. These results provide novel insights into the molecular action of TSH and signaling downstream for TSHR in non-thyroid cells. Fibrocytes neither express adenylate cyclase nor generate cAMP and thus these findings are free from any influence of cAMP-related signaling. They identify potential therapeutic targets for TAO. PMID:24086448

  17. Thyrotropin regulates IL-6 expression in CD34+ fibrocytes: clear delineation of its cAMP-independent actions.

    PubMed

    Raychaudhuri, Nupur; Fernando, Roshini; Smith, Terry J

    2013-01-01

    IL-6 plays diverse roles in normal and disease-associated immunity such as that associated with Graves' disease (GD). In that syndrome, the orbit undergoes remodeling during a process known as thyroid-associated ophthalmopathy (TAO). Recently, CD34(+) fibrocytes were found to infiltrate the orbit in TAO where they transition into CD34(+) orbital fibroblasts. Surprisingly, fibrocytes display high levels of functional thyrotropin receptor (TSHR), the central antigen in GD. We report here that TSH and the pathogenic anti-TSHR antibodies that drive hyperthyroidism in GD induce IL-6 expression in fibrocytes and orbital fibroblasts. Unlike TSHR signaling in thyroid epithelium, that occurring in fibrocytes is completely independent of adenylate cyclase activation and cAMP generation. Instead TSH activates PDK1 and both AKT/PKB and PKC pathways. Expression and use of PKC?II switches to that of PKCµ as fibrocytes transition to TAO orbital fibroblasts. This shift is imposed by CD34(-) orbital fibroblasts but reverts when CD34(+) fibroblasts are isolated. The up-regulation of IL-6 by TSH results from coordinately enhanced IL-6 gene promoter activity and increased IL-6 mRNA stability. TSH-dependent IL-6 expression requires activity at both CREB (-213 to -208 nt) and NF-?B (-78 to -62 nt) binding sites. These results provide novel insights into the molecular action of TSH and signaling downstream for TSHR in non-thyroid cells. Fibrocytes neither express adenylate cyclase nor generate cAMP and thus these findings are free from any influence of cAMP-related signaling. They identify potential therapeutic targets for TAO. PMID:24086448

  18. Spectroscopic Investigations on Ln(Zr1\\/3Ti2\\/3)TaO6 (Ln = Ce, Pr, Nd and Eu) Ceramics

    Microsoft Academic Search

    Annamma John; Sam Solomon; H. Padma Kumar; M. K. Suresh; A. S. Deepa; J. K. Thomas

    2008-01-01

    In the present work, the authors have performed vibrational spectroscopic study of Ln(Zr1\\/3Ti2\\/3)TaO6 (Ln = Ce, Pr, Nd and Eu) ceramics by analyzing their Raman spectra. An attempt is made to correlate the structure and microwave dielectric properties of the samples with their vibrational spectroscopic characteristics. The Raman spectra are analyzed mainly on the basis of TaO6 octahedra. Zr substitution

  19. Spectroscopic Investigations on Ln(Zr1?3Ti2?3)TaO6 (Ln = Ce, Pr, Nd and Eu) Ceramics

    Microsoft Academic Search

    Annamma John; Sam Solomon; H. Padma Kumar; M. K. Suresh; A. S. Deepa; J. K. Thomas

    2008-01-01

    In the present work, the authors have performed vibrational spectroscopic study of Ln(Zr1?3Ti2?3)TaO6 (Ln = Ce, Pr, Nd and Eu) ceramics by analyzing their Raman spectra. An attempt is made to correlate the structure and microwave dielectric properties of the samples with their vibrational spectroscopic characteristics. The Raman spectra are analyzed mainly on the basis of TaO6 octahedra. Zr substitution

  20. [Thyroid associated orbitopathy: from diagnosis to treatment].

    PubMed

    Hamédani, M; Obéric, A

    2013-01-01

    Mild to moderate forms of orbitopathy are common in auto-immune thyroid diseases, whereas severe forms are rare. Euthyroidism restoration, no smoking, and ocular local lubricants are necessary for all the patients. In case of mild orbitopathy, treatment by selenium is now indicated. Active forms of thyroid orbitopathy are better treated by IV steroids. Surgery is indicated in optic neuropathy resistant to steroids and in sequellar forms of the disease. PMID:23367708

  1. Realization of a reversible switching in TaO2 polymorphs via Peierls distortion for resistance random access memory

    NASA Astrophysics Data System (ADS)

    Zhu, Linggang; Zhou, Jian; Guo, Zhonglu; Sun, Zhimei

    2015-03-01

    Transition-metal-oxide based resistance random access memory (RRAM) is a promising candidate for next-generation universal non-volatile memories. Searching and designing appropriate materials used in the memories becomes an urgent task. Here, a structure with the TaO2 formula was predicted using evolutionary algorithms in combination with first-principles calculations. This triclinic structure (T-TaO2) is both energetically and dynamically more favorable than the commonly believed rutile structure (R-TaO2). The metal-insulator transition (MIT) between metallic R-TaO2 and T-TaO2 (band gap: 1.0 eV) is via a Peierls distortion, which makes TaO2 a potential candidate for RRAM. The energy barrier for the reversible phase transition is 0.19 eV/atom and 0.23 eV/atom, respectively, suggesting low power consumption for the resistance switch. The present findings about the MIT as the resistance-switch mechanism in Ta-O system will stimulate experimental work to fabricate tantalum oxides based RRAM.

  2. MiniTAO/MAX38 first light: 30-micron band observations from the ground-based telescope

    NASA Astrophysics Data System (ADS)

    Nakamura, Tomohiko; Miyata, Takashi; Sako, Shigeyuki; Asano, Kentaro; Uchiyama, Mizuho; Tanabe, Toshihiko; Yoneda, Mizuki; Ita, Yoshifusa; Onaka, Takashi; Kataza, Hirokazu; Aoki, Tsutomu; Doi, Mamoru; Handa, Toshihiro; Kato, Daisuke; Kawara, Kimiaki; Kohno, Kotaro; Konishi, Masahiro; Koshida, Shintaro; Minezaki, Takeo; Mitani, Natsuko; Motohara, Kentaro; Ohsawa, Ryo; Soyano, Takao; Tanaka, Masuo; Tarusawa, Ken'ichi; Toshikawa, Koji; Yoshii, Yuzuru

    2010-07-01

    We successfully carried out 30-micron observations from the ground-based telescope for the first time with our newly developed mid-infrared instrument, MAX38, which is mounted on the University of Tokyo Atacama 1.0-m telescope (miniTAO telescope). Thanks to the high altitude of the miniTAO (5,640m) and dry weather condition of the Atacama site, we can access the 30-micron wavelength region from ground-based telescopes. To achieve the observation at 30- micron wavelength, remarkable devices are employed in MAX38. First, a Si:Sb 128x128 array detector is installed which can detect long mid-infrared light up to 38-micron. Second, we developed metal mesh filters for 30-micron region band-pass filter, which are composed of several gold thin-films with cross-shaped holes. Third, a cold chopper, a 6-cm square plane mirror controlled by a piezoelectric actuator, is built into the MAX38 optics for canceling out the atmospheric turbulence noise. It enables square-wave chopping with a 50-arcsecound throw at a frequency more than 5- Hz. Finally, a low-dispersion grism spectrometer (R~50) will provide information on the transmission spectrum of the terrestrial atmosphere in 20 to 40 micron. In this observation, we clearly demonstrated that the atmospheric windows around 30-micron can be used for the astronomical observations at the miniTAO site.

  3. ANIR: Atacama near-infrared camera for the 1.0 m miniTAO telescope

    NASA Astrophysics Data System (ADS)

    Konishi, Masahiro; Motohara, Kentaro; Tateuchi, Ken; Takahashi, Hidenori; Kitagawa, Yutaro; Kato, Natsuko; Sako, Shigeyuki; Uchimoto, Yuka K.; Toshikawa, Koji; Ohsawa, Ryou; Yamamuro, Tomoyasu; Asano, Kentaro; Ita, Yoshifusa; Kamizuka, Takafumi; Komugi, Shinya; Koshida, Shintaro; Manabe, Sho; Matsunaga, Noriyuki; Minezaki, Takeo; Morokuma, Tomoki; Nakashima, Asami; Takagi, Toshinobu; Tanabé, Toshihiko; Uchiyama, Mizuho; Aoki, Tsutomu; Doi, Mamoru; Handa, Toshihiro; Kato, Daisuke; Kawara, Kimiaki; Kohno, Kotaro; Miyata, Takashi; Nakamura, Tomohiko; Okada, Kazushi; Soyano, Takao; Tamura, Yoichi; Tanaka, Masuo; Tarusawa, Ken'ichi; Yoshii, Yuzuru

    2015-02-01

    We have developed a near-infrared camera called ANIR (Atacama Near-InfraRed camera) for the University of Tokyo Atacama Observatory 1.0 m telescope (miniTAO) installed at the summit of Cerro Chajnantor (5640 m above sea level) in the north of Chile. The camera provides a field of view of 5{^'.}1 × 5{^'.}1 with a spatial resolution of 0{^''.}298 pixel-1 in the wavelength range of 0.95 to 2.4 ?m, using Offner relay optics and a PACE HAWAII-2 focal plane array. Taking advantage of the dry site, the camera is capable of narrow-band imaging observations at the hydrogen Paschen-? (Pa?, ? = 1.8751 ?m in air) wavelength ground-based observations of which have been quite difficult due to deep atmospheric absorption, mainly from water vapor. We have been successfully obtaining Pa? images of Galactic objects and nearby galaxies since the first-light observation in 2009 with ANIR. The throughputs at the narrow-band filters (N1875, N191) including the atmospheric absorption show larger dispersion (˜ 10%) than those at broad-band filters (a few percent), indicating that they are affected by temporal fluctuations in precipitable water vapor (PWV) above the site. We evaluate the PWV content via the atmospheric transmittance at the narrow-band filters, and deduce that the median and the dispersion of the distribution of the PWV are 0.40 ± 0.30 and 0.37 ± 0.21 mm, for the N1875 and N191 data respectively, which are remarkably smaller (49% ± 38% for N1875 and 59% ± 26% for N191) than radiometry measurements at the base of Cerro Chajnantor (an altitude of 5100 m). The decrease in PWV can be explained by the altitude of the site when we assume that the vertical distribution of the water vapor is approximated at an exponential profile with scale heights within 0.3-1.9 km (previously observed values at night). We thus conclude that miniTAO/ANIR at the summit of Cerro Chajnantor indeed provides us an excellent capability for a ground-based Pa? observation.

  4. Search for Small Trans-Neptunian Objects by the TAOS Project

    SciTech Connect

    Chen, Wen-Ping; Alcock, C.; Axelrod, T.; Bianco, F.B.; Byun, Y.I.; Chang, Y.H.; Cook, K.H.; Dave, R.; Giammarco, J.; Kim, D.W.; King, S.K.; Lee, T.; Lehner, M.; Lin,; Lin, H.C.; Lissauer, J.J.; Marshall, S.; Meinshausen, N.; Mondal, S.; de Pater, I.; Porrata, R.; /Taiwan, Natl. Central U. /Harvard-Smithsonian Ctr. Astrophys. /Arizona U.

    2006-12-04

    The Taiwan-America Occultation Survey (TAOS) aims to determine the number of small icy bodies in the outer reach of the Solar System by means of stellar occultation. An array of 4 robotic small (D=0.5 m), wide-field (f/1.9) telescopes have been installed at Lulin Observatory in Taiwan to simultaneously monitor some thousand of stars for such rare occultation events. Because a typical occultation event by a TNO a few km across will last for only a fraction of a second, fast photometry is necessary. A special CCD readout scheme has been devised to allow for stellar photometry taken a few times per second. Effective analysis pipelines have been developed to process stellar light curves and to correlate any possible flux changes among all telescopes. A few billion photometric measurements have been collected since the routine survey began in early 2005. Our preliminary result of a very low detection rate suggests a deficit of small TNOs down to a few km size, consistent with the extrapolation of some recent studies of larger (30-100 km) TNOs.

  5. ANIR : Atacama Near-Infrared Camera for the 1.0-m miniTAO Telescope

    E-print Network

    Konishi, Masahiro; Tateuchi, Ken; Takahashi, Hidenori; Kitagawa, Yutaro; Kato, Natsuko; Sako, Shigeyuki; Uchimoto, Yuka K; Toshikawa, Koji; Ohsawa, Ryou; Yamamuro, Tomoyasu; Asano, Kentaro; Ita, Yoshifusa; Kamizuka, Takafumi; Komugi, Shinya; Koshida, Shintaro; Manabe, Sho; Matsunaga, Noriyuki; Minezaki, Takeo; Morokuma, Tomoki; Nakashima, Asami; Takagi, Toshinobu; Tanabé, Toshihiko; Uchiyama, Mizuho; Aoki, Tsutomu; Doi, Mamoru; Handa, Toshihiro; Kato, Daisuke; Kawara, Kimiaki; Kohno, Kotaro; Miyata, Takashi; Nakamura, Tomohiko; Okada, Kazushi; Soyano, Takao; Tamura, Yoichi; Tanaka, Masuo; Tarusawa, Ken'ichi; Yoshii, Yuzuru

    2015-01-01

    We have developed a near-infrared camera called ANIR (Atacama Near-InfraRed camera) for the University of Tokyo Atacama Observatory 1.0m telescope (miniTAO) installed at the summit of Cerro Chajnantor (5640 m above sea level) in northern Chile. The camera provides a field of view of 5'.1 $\\times$ 5'.1 with a spatial resolution of 0".298 /pixel in the wavelength range of 0.95 to 2.4 $\\mu$m. Taking advantage of the dry site, the camera is capable of hydrogen Paschen-$\\alpha$ (Pa$\\alpha$, $\\lambda=$1.8751 $\\mu$m in air) narrow-band imaging observations, at which wavelength ground-based observations have been quite difficult due to deep atmospheric absorption mainly from water vapor. We have been successfully obtaining Pa$\\alpha$ images of Galactic objects and nearby galaxies since the first-light observation in 2009 with ANIR. The throughputs at the narrow-band filters ($N1875$, $N191$) including the atmospheric absorption show larger dispersion (~10%) than those at broad-band filters (a few %), indicating that ...

  6. Mid-infrared Monitoring Observations of Circumstellar Disks with TAO/MIMIZUKU

    NASA Astrophysics Data System (ADS)

    Sako, Shigeyuki; Miyata, Takashi; Kamizuka, Takafumi; Nakamura, Tomohiko; Asano, Kentaro; Uchiyama, Mizuho; Okada, Kazushi; Onaka, Takashi; Sakon, Itsuki; Kataza, Hirokazu; Yoshii, Yuzuru

    2013-07-01

    Mid-infrared variabilities of dust continuum and features in time scale of days to years have been found in circumstellar disks around YSOs and debris disks by multi-epoch studies with recent space missions such as AKARI, WISE, Spitzer, and Herschel (e.g., Dahm+09, Espaillat+11, Flaherty+12, Melis+12). However, physical mechanisms leading to the rapid MIR variabilities are still unclear because of sparse data sampling. More frequent and long-term observations with ground-based MIR instruments are required. Meanwhile, fast fluctuation of atmospheric water vapor affects photometric accuracy in the MIR observations from the ground. In order to monitor the variabilities of a few percent level as detected by the space telescopes, improvements of observation methods are needed. We have been developing a new MIR instrument MIMIZUKU (Kamizuka+12, Miyata+10) mounted on 6.5-m TAO telescope (Yoshii+10), which will be constructed at a 5,640-m altitude site in Atacama, Chile, and 8.2-m Subaru telescope in Hawaii. The MIMIZUKU has unique equipment called Field Stacker which enables simultaneous observations of target and reference objects owing to focusing two separated field-of-views on a same detector. The simultaneity improves the photometric accuracy and realizes stable long-term monitoring. We will carry out MIR monitoring observations of dust emission from the circumstellar disks and the debris disks with the imaging and low-resolution spectroscopic modes of the MIMIZUKU. The time-variable emissions from the YSOs could allow us to reveal formation and destruction mechanism of dust grains in the inner disk region. In observations of debris disks, fresh dust formed by large collisions in a planetary disk is expected to be detected.

  7. Upper Limits on the Number of Small Bodies in Sedna-Like Orbits by the TAOS Project

    SciTech Connect

    Wang, J; Lehner, M J; Zhang, Z; Bianco, F B; Alcock, C; Chen, W; Axelrod, T; Byun, Y; Coehlo, N K; Cook, K H; Dave, R; de Pater, L; Porrata, R; Kim, D; King, S; Lee, T; Lin, H; Lissauer, J J; Marshall, S L; Protopapas, P; Rice, J A; Schwamb, M E; Wang, S; Wen, C

    2009-11-13

    We present the results of a search for occultation events by objects at distances between 100 and 1000 AU in lightcurves from the Taiwanese-American Occultation Survey (TAOS). We searched for consecutive, shallow flux reductions in the stellar lightcurves obtained by our survey between 7 February 2005 and 31 December 2006 with a total of {approx} 4.5 x 10{sup 9} three-telescope simultaneous photometric measurements. No events were detected, allowing us to set upper limits on the number density as a function of size and distance of objects in Sedna-like orbits, using simple models.

  8. Preparation and structure refinement of KTi 3TaO 9 and K 3TiTa 7O 21

    NASA Astrophysics Data System (ADS)

    Gatehouse, B. M.; Nesbit, M. C.

    1981-08-01

    KTi 3TaO 9 crystallizes in the orthorhombic system with unit-cell dimensions a = 6.392(2), b = 3.793(1), c = 14.877(4) Å, z = 2 and space group Pnmm. K 3TiTa 7O 21 crystallizes in the hexagonal system with unit-cell dimensions a = 9.095(3), c = 12.063(4) Å, z = 2 and space group {P6 3}/{mcm}. The structures were solved by conventional Patterson and Fourier techniques, the former, using 283 unique reflections ( I ? 3 ? ( I)), was refined by full-matrix least-squares techniques to an R of 0.0551 ( Rw = 0.0496), the latter, using 343 unique reflections ( I ? 3 ? ( I)), was refined using the same technique to an R of 0.0354 ( Rw = 0.0279). Intensity data were measured using counter methods and the "?" scan technique. KTi 3TaO 9 is isostructural with KTi 3NbO 9, whose structure was previously derived from powder data; and K 3TiTa 7O 21 adopts the same structure as found for the nonstoichiometric phase K 5.5Ta 15.7O 42 in this laboratory. Both materials were obtained as single crystals by the use of a flux in their preparation. The distribution of titanium and tantalum over the octahedral sites is discussed relative to previously determined structures.

  9. Evaluation of a hybrid satellite- and NWP-based turbulent heat flux product using Tropical Atmosphere-Ocean (TAO) buoys

    NASA Astrophysics Data System (ADS)

    Jiang, Chuanli; Cronin, Meghan F.; Kelly, Kathryn A.; Thompson, Luanne

    2005-09-01

    Gridded hybrid turbulent heat flux fields were created by applying the state-of-the-art Coupled Ocean-Atmosphere Response Experiment (COARE) version 3.0 bulk algorithm to state variables (sea surface temperature, winds relative to currents, air temperature, and air specific humidity) derived from either numerical weather prediction (NWP) reanalysis (National Centers for Environmental Prediction-National Center for Atmospheric Research (NCEP-NCAR) reanalysis (NCEP1), NCEP reanalysis-2 (NCEP2), and 40-year European Centre for Medium-Range Weather Forecasts (ECMWF) reanalysis (ERA40)) or satellite sensors (QuikSCAT winds and Tropical Rainfall Measuring Mission (TRMM) Microwave Imager microwave sea surface temperature). The most accurate source for each state variable was determined by comparing variables to tropical Pacific Tropical Atmosphere-Ocean (TAO) buoy observations for the years 2000-2001. The selected sources were as follows: QuikSCAT for winds relative to currents, ERA40 for air temperature and specific humidity, and TRMM Microwave Imager fusion product for sea surface temperature. Errors in latent and sensible heat fluxes to state variables were analyzed. Specific humidity errors contributed the most to errors in latent heat flux (LHF). Overall, the hybrid LHF product had a bias of -5.8 W m-2 and a standard deviation of difference of 16.2 W m-2, which is comparable to the accuracy of LHF derived from TAO measurements.

  10. Arsenic Removal from Drinking Water by Adsorptive Media - U.S. EPA Demonstration Project at Taos, NM, Final Performance Evaluation Report

    EPA Science Inventory

    This report documents the activities performed and the results obtained for the EPA arsenic removal technology demonstration project at the Town of Taos in New Mexico. The main objective of the project was to evaluate the effectiveness of Severn Trent Services? (STS) SORB 33? ad...

  11. Spectrum Prediction in Cognitive Radio Networks Xiaoshuang Xing1,Tao Jing1,Wei Cheng2 Yan Huo1, Xiuzhen Cheng3

    E-print Network

    Cheng, Xiuzhen "Susan"

    Spectrum Prediction in Cognitive Radio Networks Xiaoshuang Xing1,Tao Jing1,Wei Cheng2 Yan Huo1}@bjtu.edu.cn, wcheng@cs.uml.edu, yhuo@bjtu.edu.cn, cheng@gwu.edu Abstract--Spectrum sensing, spectrum decision, spectrum sharing, and spectrum mobility are four major functions of cognitive radio (CR) systems. Spectrum

  12. Vanadium-based Ohmic contacts to n-AlGaN in the entire alloy composition Ryan France, Tao Xu, Papo Chen, R. Chandrasekaran, and T. D. Moustakasa

    E-print Network

    Vanadium-based Ohmic contacts to n-AlGaN in the entire alloy composition Ryan France, Tao Xu, Papo for films from 95%­100% AlN mole fraction. These results were accounted for by hypothesizing that vanadium, upon annealing, interacts with the nitride film and forms vanadium nitride, which is consistent

  13. TAO, Vol. 17, No. 2, 345-351, June 2006 Ionospheric Disturbances Triggered by the Mw7.6 Earthquake off the

    E-print Network

    . Results show that the average speeds of the seismo-ionospheric disturbances traveling in the up- per345 TAO, Vol. 17, No. 2, 345-351, June 2006 Ionospheric Disturbances Triggered by the Mw7-based receivers of the global positioning sys- tem (GPS) was use to detect seismo-ionospheric disturbances

  14. Mining Test Oracles of Web Search Engines Wujie Zheng1, Hao Ma2, Michael Lyu1, Tao Xie3, and Irwin King1,4

    E-print Network

    Xie, Tao

    Mining Test Oracles of Web Search Engines Wujie Zheng1, Hao Ma2, Michael Lyu1, Tao Xie3, and Irwin search results? Related Work · Multiple implementation testing: search engines often disagree with each oracles from multiple search engines' information Our Approach · Mapping queries and search results

  15. Viscous effects in droplet-ejecting capillary waves Christopher L. Goodridge,* W. Tao Shi, H. G. E. Hentschel, and Daniel P. Lathrop

    E-print Network

    Lathrop, Daniel P.

    Viscous effects in droplet-ejecting capillary waves Christopher L. Goodridge,* W. Tao Shi, H. G. E and described 7­12 . Specifically in this study, capillary waves experience a transition from a turbulent non. The transition to droplet-ejecting states in capillary sur- face waves is induced by increasing the applied

  16. Automated classification of single airborne particles from two-dimensional angle-resolved optical scattering (TAOS) patterns by non-linear filtering

    NASA Astrophysics Data System (ADS)

    Crosta, Giovanni Franco; Pan, Yong-Le; Aptowicz, Kevin B.; Casati, Caterina; Pinnick, Ronald G.; Chang, Richard K.; Videen, Gorden W.

    2013-12-01

    Measurement of two-dimensional angle-resolved optical scattering (TAOS) patterns is an attractive technique for detecting and characterizing micron-sized airborne particles. In general, the interpretation of these patterns and the retrieval of the particle refractive index, shape or size alone, are difficult problems. By reformulating the problem in statistical learning terms, a solution is proposed herewith: rather than identifying airborne particles from their scattering patterns, TAOS patterns themselves are classified through a learning machine, where feature extraction interacts with multivariate statistical analysis. Feature extraction relies on spectrum enhancement, which includes the discrete cosine FOURIER transform and non-linear operations. Multivariate statistical analysis includes computation of the principal components and supervised training, based on the maximization of a suitable figure of merit. All algorithms have been combined together to analyze TAOS patterns, organize feature vectors, design classification experiments, carry out supervised training, assign unknown patterns to classes, and fuse information from different training and recognition experiments. The algorithms have been tested on a data set with more than 3000 TAOS patterns. The parameters that control the algorithms at different stages have been allowed to vary within suitable bounds and are optimized to some extent. Classification has been targeted at discriminating aerosolized Bacillus subtilis particles, a simulant of anthrax, from atmospheric aerosol particles and interfering particles, like diesel soot. By assuming that all training and recognition patterns come from the respective reference materials only, the most satisfactory classification result corresponds to 20% false negatives from B. subtilis particles and <11% false positives from all other aerosol particles. The most effective operations have consisted of thresholding TAOS patterns in order to reject defective ones, and forming training sets from three or four pattern classes. The presented automated classification method may be adapted into a real-time operation technique, capable of detecting and characterizing micron-sized airborne particles.

  17. Dietary shift in corallivorous Drupella snails following a major bleaching event at Koh Tao, Gulf of Thailand

    NASA Astrophysics Data System (ADS)

    Hoeksema, B. W.; Scott, C.; True, J. D.

    2013-06-01

    The island Koh Tao in the western Gulf of Thailand suffered severe coral bleaching in 2010. Its mushroom coral fauna of 20 species was surveyed during the bleaching in 2010 and after the bleaching in 2011. Multi-species assemblages of free-living mushroom corals occurred around the island, two of which were invaded by corallivorous Drupella snails after the bleaching. Previously these gastropods were known to mainly consume branching corals and hardly any mushroom corals. The snails were found preying on four fungiid species, three of which were susceptible to bleaching. The dietary shift became apparent after populations of preferred prey species (Acroporidae and Pocilloporidae) had died during the bleaching event. It seems that bleaching mortality reduced the availability of preferred prey, causing the corallivores to switch to less preferred species that occur in dense aggregations.

  18. THE TAOS PROJECT: UPPER BOUNDS ON THE POPULATION OF SMALL KUIPER BELT OBJECTS AND TESTS OF MODELS OF FORMATION AND EVOLUTION OF THE OUTER SOLAR SYSTEM

    SciTech Connect

    Bianco, F. B. [Department of Physics, University of California Santa Barbara, Mail Code 9530, Santa Barbara, CA 93106-9530 (United States); Zhang, Z.-W.; King, S.-K.; Wang, J.-H.; Lee, T.; Lin, H.-C. [Institute of Astronomy and Astrophysics, Academia Sinica, P.O. Box 23-141, Taipei 10617, Taiwan (China); Lehner, M. J. [Department of Physics and Astronomy, University of Pennsylvania, 209 South 33rd Street, Philadelphia, PA 19104 (United States); Mondal, S. [Aryabhatta Research Institute of Observational Sciences (ARIES), Manora Peak, Nainital 263 129 (India); Giammarco, J. [Department of Astronomy and Physics, Eastern University, 1300 Eagle Road, Saint Davids, PA 19087 (United States); Holman, M. J.; Alcock, C. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Coehlo, N. K. [Department of Statistics, University of California-Berkeley, 367 Evans Hall, Berkeley, CA 94720 (United States); Axelrod, T. [Steward Observatory, 933 North Cherry Avenue, Room N204, Tucson, AZ 85721 (United States); Byun, Y.-I.; Kim, D.-W. [Department of Astronomy, Yonsei University, 134 Shinchon, Seoul 120-749 (Korea, Republic of); Chen, W. P. [Institute of Astronomy, National Central University, 300 Jhongda Road, Jhongli 32054, Taiwan (China); Cook, K. H. [Institute for Geophysics and Planetary Physics, Lawrence Livermore National Laboratory, Livermore, CA 94550 (United States); Dave, R. [Initiative in Innovative Computing at Harvard, 60 Oxford Street, Cambridge, MA 02138 (United States); De Pater, I. [Department of Astronomy, University of California-Berkeley, 601 Campbell Hall, Berkeley, CA 94720 (United States); Lissauer, J. J. [Space Science and Astrobiology Division 245-3, NASA Ames Research Center, Moffett Field, CA 94035 (United States)], E-mail: fbianco@lcogt.net (and others)

    2010-04-15

    We have analyzed the first 3.75 years of data from the Taiwanese American Occultation Survey (TAOS). TAOS monitors bright stars to search for occultations by Kuiper Belt objects (KBOs). This data set comprises 5 x 10{sup 5} star hours of multi-telescope photometric data taken at 4 or 5 Hz. No events consistent with KBO occultations were found in this data set. We compute the number of events expected for the Kuiper Belt formation and evolution models of Pan and Sari, Kenyon and Bromley, Benavidez and Campo Bagatin, and Fraser. A comparison with the upper limits we derive from our data constrains the parameter space of these models. This is the first detailed comparison of models of the KBO size distribution with data from an occultation survey. Our results suggest that the KBO population is composed of objects with low internal strength and that planetary migration played a role in the shaping of the size distribution.

  19. Changes in electronic structure upon lithium insertion reaction into the A-site-deficient perovskite-type oxides, Gd 1\\/3TaO 3

    Microsoft Academic Search

    Kazuomi Imaki; Masanobu Nakayama; Yoshiharu Uchimoto; Masataka Wakihara

    2004-01-01

    Electrochemical behavior and the variation of electronic structure upon lithium insertion into the A-site-deficient perovskite oxide, Gd1\\/3TaO3, have been studied by X-ray absorption spectroscopy (XAS). During electrochemical lithium insertion, Gd LIII-edge and Ta LI-edge XAS revealed that Gd ion did not contribute the charge compensation, while Ta ion reduced its oxidation state. Furthermore, the changes in O K-edge spectra with

  20. Practical Control Flow Integrity & Randomization for Binary Executables Chao Zhang1, Tao Wei1,2, Zhaofeng Chen1, Lei Duan1,

    E-print Network

    Sekar, R.

    ,2, Zhaofeng Chen1, Lei Duan1, L´aszl´o Szekeres2,3+, Stephen McCamant2,4+, Dawn Song2, Wei Zou1 1 Beijing KeyPractical Control Flow Integrity & Randomization for Binary Executables Chao Zhang1, Tao Wei1 *Corresponding author. Email: lenx.wei@gmail.com +Work done while the authors were at UC Berkeley. that all

  1. Effect of tao-hong-si-wu-tang, a traditional Chinese herbal medicine formula, on physical fatigue in mice.

    PubMed

    Li, Shan-shan; Chen, Zi-chao; Zhang, Chao-hui

    2012-01-01

    Tao-Hong-Si-Wu-Tang (THSWT) is a famous traditional Chinese herbal medicine formula, which has traditionally been used in China for about one thousand years. The present study investigated the effect of THSWT on physical fatigue. 32 male mice were randomly divided into 4 groups with 8 in each group. All were administered orally and daily for 28 days. Group I received isotonic saline solution as control; Group II, III and IV obtained 5, 10 and 20ml/ kg body weight of THSWT solutions, respectively. After 28 days, the anti-physical fatigue effect of THSWT was evaluated by using a forced swimming test, along with the determination of blood lactic acid, blood urea nitrogen (BUN), liver glycogen and muscle glycogen contents. The data showed that THSWT could extend exhaustive swimming time of mice, as well as decrease the BLA and BUN contents and increase the liver glycogen and muscle glycogen contents. The results support that THSWT had anti-physical fatigue effect. PMID:24082327

  2. Optical characterization and evaluation of the laser properties of Yb3 + -doped (La, Sr)(Al, Ta)O3 single crystals

    NASA Astrophysics Data System (ADS)

    Zhao, Chengchun; Hang, Yin; He, Xiaoming; Zhang, Lianhan; Yin, Jigang; Hu, Pengchao; He, Mingzhu; Ma, En

    2011-03-01

    A Yb3 + -doped mixed-perovskite single crystal (La, Sr)(Al, Ta)O3 (LSAT) crystal is grown by the Czochralski method. The absorption spectrum, fluorescence spectrum and fluorescence lifetime of Yb3 + ions have been investigated, and the spectroscopic parameters of Yb:LSAT have also been calculated. This crystal exhibits a remarkably large ground-state splitting (about 1100 cm - 1), a relatively long fluorescence lifetime (0.85 ms) and broad absorption and emission bandwidths. The results indicate that the Yb3 + :LSAT crystal is a good candidate for diode-pumped ultrashort and tunable solid-state laser applications.

  3. Optical characterization and evaluation of the laser properties of Yb(3+)-doped (La, Sr)(Al, Ta)O(3) single crystals.

    PubMed

    Zhao, Chengchun; Hang, Yin; He, Xiaoming; Zhang, Lianhan; Yin, Jigang; Hu, Pengchao; He, Mingzhu; Ma, En

    2011-03-30

    A Yb(3+)-doped mixed-perovskite single crystal (La, Sr)(Al, Ta)O(3) (LSAT) crystal is grown by the Czochralski method. The absorption spectrum, fluorescence spectrum and fluorescence lifetime of Yb(3+) ions have been investigated, and the spectroscopic parameters of Yb:LSAT have also been calculated. This crystal exhibits a remarkably large ground-state splitting (about 1100 cm(-1)), a relatively long fluorescence lifetime (0.85 ms) and broad absorption and emission bandwidths. The results indicate that the Yb(3+):LSAT crystal is a good candidate for diode-pumped ultrashort and tunable solid-state laser applications. PMID:21378445

  4. Spectroscopic Investigations on Ln(Zr1/3Ti2/3)TaO6 (Ln = Ce, Pr, Nd and Eu) Ceramics

    NASA Astrophysics Data System (ADS)

    John, Annamma; Solomon, Sam; Kumar, H. Padma; Suresh, M. K.; Deepa, A. S.; Thomas, J. K.

    2008-11-01

    In the present work, the authors have performed vibrational spectroscopic study of Ln(Zr1/3Ti2/3)TaO6 (Ln = Ce, Pr, Nd and Eu) ceramics by analyzing their Raman spectra. An attempt is made to correlate the structure and microwave dielectric properties of the samples with their vibrational spectroscopic characteristics. The Raman spectra are analyzed mainly on the basis of TaO6 octahedra. Zr substitution in LnTiTaO6 has not changed the prominent phase, however, the movement towards euxenite structure with increase in atomic number of the lanthanide has become faster. The broadening and splitting of lines observed in Nd and Eu based compounds indicate the distortion of octahedra. The negative value of ?f of Eu based compounds indicates the presence of euxenite phase in addition to the prominent aeschynite phase. This is confirmed by the maximum distortion of the octahedra as indicated by the lower wavenumber, broadening and splitting of the characteristic Raman lines. The Raman shift of ?2(Eg) mode showed a variation similar to ?r and ?f with the ionic radii of the lanthanide ions.

  5. Analysis of meteorological data and water chemistry of Latir Lakes, Taos County, New Mexico, 1985-88

    USGS Publications Warehouse

    Anderholm, S.K.; Roybal, R.G.; Risser, D.W.; Somers, Georgene

    1994-01-01

    Data were analyzed to determine the chemistry of atmospheric deposition and water of the Latir Lakes in Taos County New Mexico, from 1985 to 1988. The Latir Lakes consist of a series of nine paternoster lakes that range in altitude from 11,061 to 11,893 feet above sea level. The pH of wet precipitation generally ranged from 4.6 to 5.5 and the specific conductance of wet precipitation ranged from 1 to 18 microsiemens per centimeter at 25 degrees Celsius from December 1985 through September 1988. Snowpack chemistry data indicate a change in the specific conductance, pH, and alkalinity of the snowpack from month to month. The dominant cation in the snowpack is calcium, and the dominant anions are nitrate and sulfate. The samples having the smallest values of specific conductance generally did not contain measurable alkalinity. When the snowpack starts to melt in the spring, specific conductance of the entire snowpack decreases, consistent with the hypothesis that the initial fluid draining from the snowpack transports a large amount of dissolved material out of the snowpack. Water chemistries in the Latir Lakes are similar although specific conductance increases downstream from lake 9 to lake 1. Calcium is the dominant cation and the ions that produce alkalinity are the dominant anions. Concentrations of sodium, magnesium, chloride, and sulfate do not vary substantially from year to year or during the year in a particular lake. Alkalinity and calcium concentration, however, do vary from year to year and during the year. The pH of outflow from the Latir Lakes varies from lake to lake and from year to year. In 1986, the range in pH in the lakes was less than 1 unit in mid-June, but was greater than 2.5 units by late October. The pH generally was larger than 7.0 in all of the lakes and was as large as 9.9 in several of the lakes during the period of study. The pH of outflow water generally increases from early spring to late summer in the Latir Lakes, and snowmelt does not seem to cause the pH to decrease in the lakes. Depth profiles of selected lakes indicate that the dissolved-oxygen concentration approaches zero below the thermocline. This suggests biological oxidation of organic matter in the lower zones in these lakes. Because many organisms cannot live in water containing small dissolved-oxygen concentrations, large volumes of water in lakes 9 and 3 probably are not suitable for habitation during the summer months.

  6. 2012 European Thyroid Association Guidelines for Metastatic Medullary Thyroid Cancer

    PubMed Central

    Schlumberger, M.; Bastholt, L.; Dralle, H.; Jarzab, B.; Pacini, F.; Smit, J.W.A.

    2012-01-01

    Distant metastases are the main cause of death in patients with medullary thyroid cancer (MTC). These 21 recommendations focus on MTC patients with distant metastases and a detailed follow-up protocol of patients with biochemical or imaging evidence of disease, selection criteria for treatment, and treatment modalities, including local and systemic treatments based on the results of recent trials. Asymptomatic patients with low tumor burden and stable disease may benefit from local treatment modalities and can be followed up at regular intervals of time. Imaging is usually performed every 6–12 months, or at longer intervals of time depending on the doubling times of serum calcitonin and carcinoembryonic antigen levels. Patients with symptoms, large tumor burden and progression on imaging should receive systemic treatment. Indeed, major progress has recently been achieved with novel targeted therapies using kinase inhibitors directed against RET and VEGFR, but further research is needed to improve the outcome of these patients. PMID:24782992

  7. SDI: Solar Dome Instrument for Solar Irradiance Monitoring Tao Liu1, Ankur U. Kamthe1, Varick L. Erickson1, Carlos F. M. Coimbra2 and Alberto E. Cerpa1

    E-print Network

    Cerpa, Alberto E.

    SDI: Solar Dome Instrument for Solar Irradiance Monitoring Tao Liu1, Ankur U. Kamthe1, Varick L data for ground solar irradiance (direct normal and global irradiance) is a major obstacle for the de- velopment of adequate policies to promote and take advan- tage of existing solar technologies. Although

  8. Digital data and derivative products from a high-resolution aeromagnetic survey of the central San Luis basin, covering parts of Alamosa, Conejos, Costilla, and Rio Grande counties, Colorado, and Taos county, New Mexico

    USGS Publications Warehouse

    Bankey, Viki; Grauch, V.J.S.; Webbers, Ank; PRJ, Inc

    2005-01-01

    This report describes data collected from a high-resolution aeromagnetic survey flown over the central San Luis basin during October, 2004, by PRJ, Inc., on contract to the U.S. Geological Survey (USGS). The survey extends from just north of Alamosa, Colorado, southward to just northwest of Taos, New Mexico. It covers large parts of the San Luis Valley in Alamosa, Conejos, Costilla, and Rio Grande Counties, southern Colorado, and the Taos Plateau in Taos County, northern New Mexico. The survey was designed to complement two surveys previously acquired along the eastern borders of the San Luis Basin over the vicinities of Taos, New Mexico (Bankey and others, 2004a) and Blanca, Colorado (Bankey and others, 2004b). Our overall objective in conducting these surveys is to improve knowledge of the subsurface geologic framework in order to understand ground-water systems in populated alluvial basins along the Rio Grande. These USGS efforts are conducted in collaboration with other federal, state, and local governmental entities where possible.

  9. Decoupling of Structural and Electronic Phase Transitions in VO2 Zhensheng Tao, Tzong-Ru T. Han, Subhendra D. Mahanti, Phillip M. Duxbury, Fei Yuan, and Chong-Yu Ruan*

    E-print Network

    Wu, Junqiao

    Decoupling of Structural and Electronic Phase Transitions in VO2 Zhensheng Tao, Tzong-Ru T. Han). The structural and MIT transitions in VO2 are frequently observed to occur at the same tem- perature and have transitions. There has been extensive debate over the cause and effect relationship of the VO2 MIT, involving

  10. Amygdalin isolated from Semen Persicae (Tao Ren) extracts induces the expression of follistatin in HepG2 and C2C12 cell lines

    PubMed Central

    2014-01-01

    Background The Chinese medicine formulation ISF-1 (also known as Bu-Yang-Huan-Wu-Tang) for post-stroke rehabilitation could increase the expression of growth-regulating protein follistatin by approximately 4-fold. This study aims to identify the active compounds of ISF-1 for the induction of follistatin expression. Methods Active compounds in ISF-1 responsible for induction of follistatin were identified by a bioactivity-guided fractionation procedure involving liquid-liquid extraction, HPLC separation and RT-PCR detection. The aqueous extracts of seven ISF-1 ingredients including Semen Persicae (Tao Ren) and the S. Persicae-derived fractions were assayed for the induction of follistatin mRNA expression in human hepatocarcinoma HepG2 cells by RT-PCR. The concentrations of isolated compounds were proportionally normalized to the reported IC50 concentration (5.8 mg/mL) of the formulation ISF-1 in HepG2. The active fractions were characterized by reverse-phase HPLC on a C18 column and identified by mass spectrometry. Results Three ingredients of ISF-1, namely S. Persicae (Tao Ren), Pheretima (Di Long), and Flos Carthami (Hong Hua), induced the expression of follistatin mRNA. Among these, the ingredient S. Persicae were the most active, and amygdalin from S. Persicae extract was identified as a novel follistatin inducer. Amygdalin stimulated the growth of skeletal muscle cell line C2C12 cells in a concentration-dependent manner. Conclusions Amygdalin isolated from S. Persicae extract in ISF-1 through a bioactivity-guided fractionation procedure induced the expression of follistatin in HepG2 and C2C12 cell lines. PMID:25237385

  11. Regional vegetation dynamics and its response to climate change—a case study in the Tao River Basin in Northwestern China

    NASA Astrophysics Data System (ADS)

    Li, Changbin; Qi, Jiaguo; Yang, Linshan; Wang, Shuaibing; Yang, Wenjin; Zhu, Gaofeng; Zou, Songbing; Zhang, Feng

    2014-12-01

    The 30-year normalized-difference vegetation index (NDVI) time series from AVHRR/MODIS satellite sensors was used in this study to assess the regional vegetation dynamic changes in the Tao River Basin, which cuts across the Eastern Tibetan Plateau (ETP) and the Southwestern Loess Plateau (SLP). First, principal component and correlation analyses were carried out to determine the key climatic variables driving ecological change in the region. Then, regression models were tested to correlate NDVI with the selected climatic variables to determine their predictive power. Finally, Sen’s slope method was used to determine how terrestrial vegetation has responded to regional climate change in the region. The results indicated an average winter season NDVI value of 0.14 in the ETP but only 0.04 in the SLP. Primarily driven by increasing temperature, vegetation growth has generally been enhanced since 1981; spring NDVI increased by 0.03 every 10 years in the ETP and 0.02 in the SLP. Further, results from trend analyses suggest vegetation growth in the ETP shifted to earlier-start and earlier-end dates, however in the SLP, the growing season has been extended with an earlier-start and later-end date. The precipitation threshold for vegetation germination, measured by the cumulative spring rainfall, was found to be 44 mm for both the ETP and SLP.

  12. Serum Containing Tao-Hong-Si-Wu Decoction Induces Human Endothelial Cell VEGF Production via PI3K/Akt-eNOS Signaling

    PubMed Central

    Yin, DengKe; Liu, ZhuQing; Peng, DaiYin; Yang, Ye; Gao, XiangDong; Xu, Fan; Han, Lan

    2013-01-01

    Tao-Hong-Si-Wu decoction (TSD) is a famous traditional Chinese medicine (TCM) and widely used for ischemic disease in China. TSD medicated serum was prepared after oral administration of TSD (1.6?g/kg) twice a day for 3 days in rats. TSD medicated serum induced human umbilical vein endothelial cells (HUVECs) proliferation, VEGF secretion, and nitric oxide (NO) production. These promoted effects of TSD were partly inhibited by treatment with PI3K inhibitor (LY294002) or eNOS inhibitor (L-NAME), respectively, and completely inhibited by treatment with LY294002 and L-NAME simultaneously. Western blot analysis findings further indicated that TSD medicated serum upregulated p-Akt and p-eNOS expressions, which were significantly inhibited by LY294002 or L-NAME and completely inhibited by both LY294002 and L-NAME; these results indicated that TSD medicated serum induced HUVECs VEGF expression via PI3K/Akt-eNOS signaling. TSD medicated serum contains hydroxysafflor yellow A, ferulic acid, and ligustilide detected by UPLC with standards, so these effect of TSD medicated serum may be associated with these three active compounds absorbed in serum. PMID:23762109

  13. Neuroprotection by the Traditional Chinese Medicine, Tao-Hong-Si-Wu-Tang, against Middle Cerebral Artery Occlusion-Induced Cerebral Ischemia in Rats.

    PubMed

    Wu, Chih-Jen; Chen, Jui-Tai; Yen, Ting-Lin; Jayakumar, Thanasekaran; Chou, Duen-Suey; Hsiao, George; Sheu, Joen-Rong

    2011-01-01

    Tao-Hong-Si-Wu-Tang (THSWT) is a famous traditional Chinese medicine (TMC). In the present study, oral administration of THSWT (0.7 and 1.4?g kg(-1)day(-1)) for 14 days before MCAO dose-dependently attenuated focal cerebral ischemia in rats. MCAO-induced focal cerebral ischemia was associated with increases in hypoxia-inducible factor (HIF)-1?, inducible nitric oxide synthase (iNOS), tumor necrosis factor (TNF)-?, and active caspase-3 expressions in ischemic regions. These expressions were obviously inhibited by 0.7?g kg(-1)day(-1) THSWT treatment. In addition, THSWT inhibited platelet aggregation stimulated by collagen in washed platelets. In an in vivo study, THSWT (16?g kg(-1)) significantly prolonged platelet plug formation in mice. However, THSWT (20 and 40??g mL(-1)) did not significantly reduce the electron spin resonance (ESR) signal intensity of hydroxyl radical (OH(•)) formation. In conclusion, the most important findings of this study demonstrate for the first time that THSWT possesses potent neuroprotective activity against MCAO-induced focal cerebral ischemia in vivo. This effect may be mediated, at least in part, by the inhibition of both HIF-1? and TNF-? activation, followed by the inhibition of inflammatory responses (i.e., iNOS expression), apoptosis formation (active caspase-3), and platelet activation, resulting in a reduction in the infarct volume in ischemia-reperfusion brain injury. PMID:21076527

  14. Neuroprotection by the Traditional Chinese Medicine, Tao-Hong-Si-Wu-Tang, against Middle Cerebral Artery Occlusion-Induced Cerebral Ischemia in Rats

    PubMed Central

    Wu, Chih-Jen; Chen, Jui-Tai; Yen, Ting-Lin; Jayakumar, Thanasekaran; Chou, Duen-Suey; Hsiao, George; Sheu, Joen-Rong

    2011-01-01

    Tao-Hong-Si-Wu-Tang (THSWT) is a famous traditional Chinese medicine (TMC). In the present study, oral administration of THSWT (0.7 and 1.4?g kg?1day?1) for 14 days before MCAO dose-dependently attenuated focal cerebral ischemia in rats. MCAO-induced focal cerebral ischemia was associated with increases in hypoxia-inducible factor (HIF)-1?, inducible nitric oxide synthase (iNOS), tumor necrosis factor (TNF)-?, and active caspase-3 expressions in ischemic regions. These expressions were obviously inhibited by 0.7?g kg?1day?1 THSWT treatment. In addition, THSWT inhibited platelet aggregation stimulated by collagen in washed platelets. In an in vivo study, THSWT (16?g kg?1) significantly prolonged platelet plug formation in mice. However, THSWT (20 and 40??g mL?1) did not significantly reduce the electron spin resonance (ESR) signal intensity of hydroxyl radical (OH•) formation. In conclusion, the most important findings of this study demonstrate for the first time that THSWT possesses potent neuroprotective activity against MCAO-induced focal cerebral ischemia in vivo. This effect may be mediated, at least in part, by the inhibition of both HIF-1? and TNF-? activation, followed by the inhibition of inflammatory responses (i.e., iNOS expression), apoptosis formation (active caspase-3), and platelet activation, resulting in a reduction in the infarct volume in ischemia-reperfusion brain injury. PMID:21076527

  15. Proteomic Identification of Nrf2-Mediated Phase II Enzymes Critical for Protection of Tao Hong Si Wu Decoction against Oxygen Glucose Deprivation Injury in PC12 Cells

    PubMed Central

    Qi, Hong-yi; Li, Li; Yu, Jie; Chen, Lu; Huang, Yong-liang; Ning, Ling; Jiang, Zhuyun; Yang, Na; Xu, Xiao-yu

    2014-01-01

    Chinese herbal medicine formula Tao Hong Si Wu decoction (THSWD) is traditionally used in China for cerebrovascular diseases. However, the molecular mechanisms of THSWD associated with the cerebral ischemia reperfusion injury are largely unknown. The current study applied the two-dimensional gel electrophoresis-based proteomics to investigate the different protein profiles in PC12 cells with and without the treatment of THSWD. Twenty-six proteins affected by THSWD were identified by MALDI-TOF mass spectrometry. Gene ontology analysis showed that those proteins participated in several important biological processes and exhibited diverse molecular functions. In particular, six of them were found to be phase II antioxidant enzymes, which were regulated by NF-E2-related factor-2 (Nrf2). Quantitative PCR further confirmed a dose-dependent induction of the six phase II enzymes by THSWD at the transcription level. Moreover, the individual ingredients of THSWD were discovered to synergistically contribute to the induction of phase II enzymes. Importantly, THSWD's protection against oxygen-glucose deprivation-reperfusion (OGD-Rep) induced cell death was significantly attenuated by antioxidant response element (ARE) decoy oligonucleotides, suggesting the protection of THSWD may be likely regulated at least in part by Nrf2-mediated phase II enzymes. Thus, our data will help to elucidate the molecular mechanisms underlying the neuroprotective effect of THSWD. PMID:24949080

  16. Protective Effects of Tao-Hong-Si-Wu Decoction on Memory Impairment and Hippocampal Damage in Animal Model of Vascular Dementia

    PubMed Central

    Han, Lan; Ji, Zhaojie; Chen, Weidong; Yin, Dengke; Xu, Fan; Li, Shanshan; Chen, Fangfang; Zhu, Guangyu; Peng, Daiyin

    2015-01-01

    Tao-Hong-Si-Wu decoction (TSD) as a traditional chinese medicine (TCM) has been developed to treat thrombotic diseases for hundreds of years, and vascular dementia (VD) is a cognitive dysfunction syndrome caused by cerebral embolism. In this study, the protective effect of TSD on memory impairment and brain damage in rat model of VD induced by middle cerebral artery occlusion (MCAO) was investigated. The study showed that rats in MCAO treatment with TSD for 14 days significantly improved behavioral function, increased densities of neuron, and induced angiogenesis in the brain compared with model rats. TSD also adjusted the neurotransmitter levels, reduced the content of endothelin-1 (ET-1), and induced the activities of vascular endothelial growth factor (VEGF) in hippocampus. Moreover, the immunohistochemical staining and western blotting results also revealed that TSD decreased apoptosis via upregulated B-cell lymphoma-2 (Bcl-2)/Bcl-2 associated X protein (Bax) ratio. These results demonstrated TSD possesses neuroprotective and antidementia properties by preventing the loss of neural cells, adjusting brain neurotransmitter, promoting cerebral blood circulation, and decreasing apoptosis. These results suggested that TSD might be developed as an effective drug for the prevention of VD.

  17. Revised specifications and current development status of MIMIZUKU: the mid-infrared instrument for the TAO 6.5-m telescope

    NASA Astrophysics Data System (ADS)

    Kamizuka, Takafumi; Miyata, Takashi; Sako, Shigeyuki; Ohsawa, Ryou; Asano, Kentaro; Uchiyama, Mizuho; Okada, Kazushi; Uchiyama, Masahito; Nakamura, Tomohiko; Sakon, Itsuki; Onaka, Takashi; Kataza, Hirokazu; Aoki, Tsutomu; Doi, Mamoru; Kato, Natsuko M.; Kawara, Kimiaki; Kitagawa, Yutaro; Kohno, Kotaro; Konishi, Masahiro; Koshida, Shintaro; Minezaki, Takeo; Morokuma, Tomoki; Motohara, Kentaro; Soyano, Takao; Takahashi, Hidenori; Tamura, Yoichi; Tanabé, Toshihiko; Tanaka, Masuo; Tarusawa, Ken'ichi; Tateuchi, Ken; Todo, Soya; Yoshii, Yuzuru

    2014-07-01

    The MIMIZUKU is the first-generation mid-infrared instrument for the TAO 6.5-m telescope. It challenges to prove the origin of dust and the formation of planets with its unique capabilities, wide wavelength coverage and precise calibration capability. The wide wavelength coverage (2-38 ?m) is achieved by three switchable cameras, NIR, MIR-S, and MIR-L. The specifications of the cameras are revised. A 5?m-cutoff HAWAII-1RG is decided to be installed in the NIR camera. The optical design of the MIR-L camera is modified to avoid detector saturation. Its final F-number is extended from 5.2 to 10.5. With these modifications, the field of view of the NIR and MIR-L camera becomes 1.2' × 1.2' and 31" × 31", respectively. The sensitivity of each camera is estimated based on the revised specifications. The precise calibration is achieved by the "Field Stacker" mechanism, which enables the simultaneous observation of the target and the calibration object in different fields. The up-and-down motion of the cryostat (~ 1 t), critical for the Field Stacker, is confirmed to have enough speed (4 mm/s) and position accuracy (~ 50 ?m). A control panel for the Field Stacker is completed, and its controllers are successfully installed. The current specifications and the development status are reported.

  18. Improved textured La 2Zr 2O 7 buffer on La 3TaO 7 seed for all-MOD Buffer/YBCO coated conductors

    NASA Astrophysics Data System (ADS)

    Parans Paranthaman, M.; Bhuiyan, M. S.; Sathyamurthy, S.; Heatherly, L.; Cantoni, C.; Goyal, A.

    2008-09-01

    The overall purpose of this research is to develop a potentially low-cost, high throughput, high yield, manufacturing process for buffer deposition, and to gain a fundamental understanding of buffer layers required for an all metal-organic deposition (MOD) based chemical solution approach. This understanding is critical to the development of a reliable, robust, low-cost, long-length manufacturing process of 2G wires. The standard RABiTS architectures consists of a starting template of biaxially textured Ni-W (5 at.%) substrate with a seed layer of Y 2O 3, a barrier layer of YSZ, and a CeO 2 cap. In this three-layer architecture, all the buffers are deposited using reactive sputtering. We have recently demonstrated that the barrier properties and the performance of MOD La 2Zr 2O 7 (LZO) match that of sputtered YSZ layers. In this work, the texture of MOD LZO was also improved by inserting a sputtered Y 2O 3 seed layer on which LZO grows without any degradation of texture. Significant improvement in the texture of sputtered Y 2O 3 seeds on NiW substrates is usually observed which is then transferred to the LZO layer. A key challenge for an all-solution approach is to replace the sputtered seed layer with a possible MOD seed layer with improved texture and on which no degradation of LZO texture occurs. Very recently, we have grown MOD La 3TaO 7 (LTO) seeds directly on biaxially textured Ni-W (3 at.%) with improved texture. In this study, we report a systematic investigation of the growth MOD LZO barrier layer on MOD LTO seeds. Preliminary results show that it is possible to grow MOD LZO with improved texture on MOD LTO seeds. This approach could be potentially used for future all MOD buffer/YBCO coated conductors.

  19. LZW Based Compressed Pattern Matching Tao Tao, Amar Mukherjee

    E-print Network

    Mukherjee, Amar

    with minimal (or no) decompression. In this paper, we report our work on compressed pattern matching in LZW initial decompression. Another fundamental problem is to develop search-aware compression algorithms) S and a pattern string (or a sub-image) P, report the occurrences of P in S with minimal (or no) decompression

  20. Validation of the NASA GEWEX-SRB Radiation Data over the Tropical Oceans: Comparisons with PIRATA, RAMA, TAO and WHOI Buoy Observations

    NASA Astrophysics Data System (ADS)

    Zhang, T.; Stackhouse, P. W.; Gupta, S. K.; Cox, S. J.; Mikovitz, J. C.

    2013-12-01

    The NASA/GEWEX SRB (Global Energy and Water Exchanges, Surface Radiation Budget) project produces and archives shortwave and longwave radiation budget flux estimates at the top of the atmosphere and at the Earth's surface. The latest version in the archive, Release 3.0, is available as 3-hourly, 3-hourly-monthly, daily and monthly means continuously over the period from July 1983 to December 2007 on a quasi-equal-area grid system of 44016 grid boxes. SRB Release 4 with further improvements in data quality and higher spatial resolution is being developed. The SRB shortwave/longwave fluxes at the Earth's surface from the algorithm GSW(V3.0)/GLW(V3.1) have been extensively validated against high-quality ground-based observations, in particular observed data from the Baseline Surface Radiation Network (BSRN). Comparisons with nearly 6000 site-months of both shortwave and longwave data from 52 BSRN sites show generally good agreement. In addition, the GEWEX SRB data have also been found to compare favorably with the World Radiation Data Centre (WRDC) data and the Global Energy Balance Archive (GEBA) data. In spite of the fact that the BSRN sites are scattered on all seven continents, the validation of the SRB data over the vast oceans had not been done until recently. In this paper, we present comparisons of the GEWEX-SRB data shortwave/longwave data with observations made on arrays moored in tropical oceans. Specifically, we have data from 21 buoys, or moorings, from Prediction and Research Moored Array in the Atlantic (PIRATA), 14 buoys from the Research Moored Array for African-Asian-Australian Monsoon Analysis and Prediction (RAMA) in the Indian Ocean, 20 buoys from the Tropical Atmosphere Ocean (TAO) array in the Pacific, and 3 buoys from the Woods Hole Oceanographic Institute (WHOI) (2 in the Pacific and 1 in the Atlantic). The data from these buoys span 12 years from 2000 to 2011, though not necessarily continuously. It is found that except for occasional outliers, the majority of the comparable pairs of data points agree well. For instance, the bias/RMS from 1644 monthly mean data points is 11.1/19.0 W m-2. Further examination of the outliers is necessary to determine whether they can be attributed to wind-driven tilt and/or aerosol accumulation on the instruments. In order to see how the ocean-based validation compares with land-based validation, we made SRB-BSRN monthly mean shortwave/longwave radiation comparisons in the tropical region only, where all the buoys are moored. The results show that in the case of shortwave radiation, the bias error from the ocean-based validation is somewhat larger than its land-based counterpart, but their RMS errors are not significantly different. In the case of longwave radiation, the ocean-based and land-based validations show nearly identical comparison statistics.

  1. Validation of the NASA GEWEX-SRB Radiation Data over the Tropical Oceans: Comparisons with PIRATA, RAMA, TAO and WHOI Buoy Observations

    NASA Astrophysics Data System (ADS)

    Zhang, T.; Stackhouse, P. W., Jr.; Gupta, S. K.; Cox, S. J.; Mikovitz, J. C.; NASA Gewex Srb Project Team

    2013-05-01

    The NASA GEWEX-SRB (Global Energy and Water Exchanges - Surface Radiation Budget) project produces and archives shortwave and longwave radiation budget data at the top of the atmosphere and the Earth's Surface. The latest version in the archive, Release 3.0, is available as 3-hourly, 3-hourly-monthly, daily and monthly means continuously over the period from July 1983 to December 2007 on a quasi-equal-area grid system of 44016 grid boxes. Releases 4 and 5 with further improved quality and higher spatial resolution are being planned. The SRB shortwave/longwave fluxes at the Earth's surface from the algorithm GSW(V3.0)/GLW(V3.1) have been extensively validated against high-quality ground-based observations, in particular observed data from the Baseline Surface Radiation Network (BSRN). Comparisons with nearly 6000 site-months of both shortwave and longwave data from 52 BSRN sites show generally good agreement. In addition, the GEWEX SRB data have also been found to compare favorably with the World Radiation Data Centre (WRDC) data and the Global Energy Balance Archive (GEBA) data. In spite of the fact that the BSRN sites are scattered on all seven continents, the validation of the SRB data over the vast oceans had not been done until recently. In this paper, we present comparisons of the GEWEX-SRB data shortwave/longwave data with observations made on arrays moored in tropical oceans. Specifically, we have data from 21 buoys, or moorings, from Prediction and Research Moored Array in the Atlantic (PIRATA), 14 buoys from the Research Moored Array for African-Asian-Australian Monsoon Analysis and Prediction (RAMA) in the Indian Ocean, 20 buoys from the Tropical Atmosphere Ocean (TAO) array in the Pacific, and 3 buoys from the Woods Hole Oceanographic Institute (WHOI) (2 in the Pacific and 1 in the Atlantic). The data from these buoys span 12 years from 2000 to 2011, though not necessarily continuously. It is found that except for occasional outliers, the majority of the comparable pairs of data points agree well. Further examination of the outliers is necessary to determine whether they can be attributed to wind-driven tilt and/or aerosol accumulation on the instruments. In order to see how the ocean-based validation compares with land-based validation, we made SRB-BSRN monthly mean shortwave/longwave radiation comparisons in the tropical region only, the region in which all the buoys are moored. The results show that in the case of shortwave radiation, the bias error from the ocean-based validation is somewhat larger than its land-based counterpart, but their RMS errors are not significantly different. In the case of longwave radiation, the ocean-based and land-based validations show nearly identical comparison statistics.

  2. Thyroid-like ophthalmopathy in a euthyroid patient receiving Ipilimumab.

    PubMed

    McElnea, Elizabeth; Ní Mhéalóid, Aine; Moran, Sarah; Kelly, Rory; Fulcher, Tim

    2014-12-01

    A 68-year-old lady with metastatic malignant melanoma was treated with Ipilimumab. She presented to Eye Casualty unable to move her eyes. Physical examination confirmed ophthalmoplegia and identified proptosis bilaterally. Radiological imaging showed bilateral enlargement of all the extra-ocular muscles suggestive of thyroid eye disease. Laboratory investigations found this patient to be euthyroid. A diagnosis of thyroid-like orbitopathy secondary to Ipilimumab therapy was made. Thyroid function tests should be performed for all patients prior to their commencement of Ipilimumab. Thyroid-like eye disease may develop in patients treated with Ipilimumab even if they remain euthyroid. PMID:25207976

  3. Gallium-67 uptake by the thyroid associated with progressive systemic sclerosis

    SciTech Connect

    Sjoberg, R.J.; Blue, P.W.; Kidd, G.S.

    1989-01-01

    Although thyroidal uptake of gallium-67 has been described in several thyroid disorders, gallium-67 scanning is not commonly used in the evaluation of thyroid disease. Thyroidal gallium-67 uptake has been reported to occur frequently with subacute thyroiditis, anaplastic thyroid carcinoma, and thyroid lymphoma, and occasionally with Hashimoto's thyroiditis and follicular thyroid carcinoma. A patient is described with progressive systemic sclerosis who, while being scanned for possible active pulmonary involvement, was found incidentally to have abnormal gallium-67 uptake only in the thyroid gland. Fine needle aspiration cytology of the thyroid revealed Hashimoto's thyroiditis. Although Hashimoto's thyroiditis occurs with increased frequency in patients with progressive systemic sclerosis, thyroidal uptake of gallium-67 associated with progressive systemic sclerosis has not, to our knowledge, been previously described. Since aggressive thyroid malignancies frequently are imaged by gallium-67 scintigraphy, fine needle aspiration cytology of the thyroid often is essential in the evaluation of thyroidal gallium-67 uptake.

  4. TAU as Tao. [interstellar spacecraft performance

    NASA Technical Reports Server (NTRS)

    Lyman, P. T.; Reid, M. S.

    1989-01-01

    This paper discusses the feasibility of building and launching a truly deep-space spacecraft mission that will penetrate near interstellar space to a depth of one thousand astronomical units (TAU) within a flight time of 50 years. Particular attention is given to the mission profile and to its communications system, power system, and propulsion system. Results of experimental studies indicate that, with advanced technology, reasonable trip times can be achieved and adequate science information can be brought to earth.

  5. The Tao of Teaching: Romance and Process.

    ERIC Educational Resources Information Center

    Schindler, Stefan

    1991-01-01

    Because college teaching aims to elevate, not entertain, it must be nourished and appreciated as a pedagogical alchemy mixing facts and feelings, ideas and skills, history and mystery. The current debate on educational reform should focus more on quality of learning experience, and on how to create and sustain it. (MSE)

  6. Tao Probing the End of the World

    E-print Network

    Kim, Sung-Soo; Yagi, Futoshi

    2015-01-01

    We introduce a new IIB 5-brane description for the E-string theory which is the world-volume theory on M5-brane probing the end of the world M9-brane. The E- string in the new realization is depicted as spiral 5-branes web equipped with the cyclic structure which is a key to uplifting to 6 dimensions. Utilizing the topological vertex to the 5-brane web configuration enables us to write down a combinatorial formula for the generating function of the E-string elliptic genera, namely the full partition function of topological strings on local 1/2 K3 surface.

  7. Tao Probing the End of the World

    E-print Network

    Sung-Soo Kim; Masato Taki; Futoshi Yagi

    2015-04-14

    We introduce a new IIB 5-brane description for the E-string theory which is the world-volume theory on M5-brane probing the end of the world M9-brane. The E- string in the new realization is depicted as spiral 5-branes web equipped with the cyclic structure which is a key to uplifting to 6 dimensions. Utilizing the topological vertex to the 5-brane web configuration enables us to write down a combinatorial formula for the generating function of the E-string elliptic genera, namely the full partition function of topological strings on local 1/2 K3 surface.

  8. UPDATES MANAGEMENT IN ENTERPRISES DATABASES Yicheng Tao

    E-print Network

    Hsu, Cheng

    and online database updates. A prime case showing this problem is the Product Data Management (PDM) system. An industrial testing (WAN) is also being conducted at Samsung Electronic Corporation for its Product Data Management system. The preliminary results reveal some highly promising improvement over the present

  9. Personalized Privacy Preservation Xiaokui Xiao Yufei Tao

    E-print Network

    Tao, Yufei

    methods focus on a universal approach that exerts the same amount of preservation for all persons, with to valuable insight into the behavior of alternative solutions. In particular, our analysis mathematically the superiority of the proposed solutions. The theoretical findings are verified with extensive experiments. 1

  10. Personalized Privacy Preservation Xiaokui Xiao Yufei Tao

    E-print Network

    Tian, Qi

    approach that exerts the same amount of preservation for all persons, with- out catering for their concrete of alternative solutions. In particular, our analysis mathematically reveals the circumstances where the previous work fails to protect privacy, and establishes the superiority of the proposed solutions

  11. External ophthalmoplegia associated with Hashimoto's thyroiditis and recovered on corticosteroid treatment.

    PubMed

    Gáti, István; Merkli, Hajnalka; Pál, Endre; Danielsson, Olof

    2012-08-01

    Five-year follow-up of a young male patient is presented. Total external ophthalmoplegia developed 1 week after an upper respiratory tract infection. After 3 years of the course, hyperthyreosis and clinical signs of thyroid-associated ophthalmopathy occurred. Hashimoto's thyroiditis and ultrastructural signs of mitochondrial damage of striated muscle were found by histological investigations. The paresis of the external ocular muscles recovered after long-term corticosteroid treatment. On the basis of clinical symptoms and histological results, the authors supposed that an immunological reaction had caused mitochondrial damage in the striated muscles, which also resulted in thyroiditis. This case history points that autoimmune mechanism more frequently might participate in the pathogenesis of chronic external ophthalmoplegia, and the symptoms might precede organ-specific or perhaps systemic autoimmune disorders. PMID:22534671

  12. Anatomy: Simple and Effective Privacy Preservation Xiaokui Xiao Yufei Tao

    E-print Network

    Tao, Yufei

    Bob's QI-values, the adversary asserts that Bob contracted pneumonia. To avoid this problem pneumonia 2 27 M 13000 dyspepsia 3 35 M 59000 dyspepsia 4 59 M 12000 pneumonia 5 61 F 54000 flu 6 65 F 25000 Disease 1 [21, 60] M [10001, 60000] pneumonia 2 [21, 60] M [10001, 60000] dyspepsia 3 [21, 60] M [10001

  13. Action Learning Guided by Tao for Lifelong Learning

    ERIC Educational Resources Information Center

    San, Sam Kong

    2006-01-01

    Information Technology brings about rapid changes in working environment, quickly rendering skills and knowledge gained in formal learning institutions obsolete. Even as they prepare students for their first career, institutions also need to equip students with skills necessary for lifelong learning. The Nanyang Technological University (NTU),…

  14. Pai-Chun Tao REYST report 06-2011

    E-print Network

    Karlsson, Brynjar

    ENERGY #12;#12;! ! ! ! ! ! ! Potential economic and environmental advantages of lithium-ion battery "#$%#&'!()**! ! ! #12;! +! #12;! ,,! ! ! Potential economic and environmental advantages of lithium-ion battery;! +,,! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! #12;! ,,,! Potential economic and environmental advantages of lithium-ion battery manufacturing using

  15. Guidelines for TSH-receptor antibody measurements in pregnancy: results of an evidence-based symposium organized by the European Thyroid Association

    Microsoft Academic Search

    Peter Laurberg; Birte Nygaard; Daniel Glinoer; Martin Grussendorf; Jacques Orgiazzi

    1998-01-01

    Hyperthyroidism due to Graves' disease is induced by autoantibodies stimulating the thyroid-stimulating hor- mone (TSH) receptor. In most patients these antibodies can be measured in serum. Graves' disease is common in women of reproductive age, with a prevalence rate of past or present disease of 0.5-1% (1). Classically, three therapeutic approaches are used: (i) Antithyroid drugs given for a long

  16. Localization of the human 64kD autoantigen D1 to myofibrils in a subset of extraocular muscle fibers

    NASA Technical Reports Server (NTRS)

    Conley, C. A.; Fowler, V. M.

    1999-01-01

    PURPOSE. To evaluate the tissue-specific expression pattern of the 64kD human autoantigen D1, a tropomodulin-related protein that may be involved in thyroid-associated ophthalmopathy. METHODS. Recombinant 64kD human autoantigen D1 was generated in a bacterial expression system and used to immunize rabbits. Specific antibodies were affinity-purified and used for Western blots on normal and hyperthyroid rat and rabbit tissue, and immunofluorescence localization on cryosections of rat tissue. RESULTS. Anti-64kD human autoantigen D1 antibodies recognize specifically a approximately 70kD polypeptide in western blots of extraocular muscle, sternothyroid muscle, and smooth muscle. Immunofluorescence staining demonstrates that the 64kD human autoantigen D1 localizes to myofibrils in slow fibers from rat extraocular and sternothyroid muscle. The level of this protein is not altered in extraocular muscles from hyperthyroid rabbits. CONCLUSIONS. The 64kD human autoantigen D1 is expressed in slow fibers of extraocular and sternothyroid muscles as a component of myofibrils, and is not upregulated in conditions of hyperthyroidism.

  17. Adventures in Data Analysis: The TAO Array and the 1997–1998 El Niño

    Microsoft Academic Search

    Stephen K. Boss

    2000-01-01

    Traditional undergraduate education in earth sciences does not emphasize data acquisition, analysis, or assessment. However, arrival of the information age dictates that earth sciences graduates be imbued with fundamental skills to organize, evaluate and process large data sets. Fortunately, the proliferation of remotely sensed data and its availability via the Internet provides many opportunities for earth science educators to meet

  18. Enforcing Resource Sharing Agreements among Distributed Server Clusters Tao Zhao and Vijay Karamcheti

    E-print Network

    Karamcheti, Vijay

    are likely to execute on platforms constructed by clustering multiple autonomous distributed servers constructed by clustering multiple, autonomous dis- tributed servers. Early evidence of this trend can governed by resource sharing agreements (also called Ser- vice Level Agreements, SLAs) between owners

  19. MCMC-BASED PEAK TEMPLATE MATCHING FOR GCXGC Mingtian Ni, Qingping Tao, and Stephen E. Reichenbach

    E-print Network

    Reichenbach, Stephen E.

    (LCP). Minimizing Hausdorff dis- tances is one of the many techniques proposed for solving the LCP. The peak template match- ing problem can be posed as the Largest Common Point Set (LCP) problem [3, 4 a subset of P to a subset of Q and minimize the distance. The solution to the LCP problem

  20. MED263: Bioinformatic Applications to Human Disease W. Andy Tao, University of Purdue

    E-print Network

    Gleeson, Joseph G.

    extract) 3) purified protein extracts (i.e. HPLC) Characterization of known proteins Analyze post Spectrometry) LC 1) reverse phase column used to reduce sample complexity. 2) typically a series of fractions from LC column are analyzed MS/MS (performed twice) 1) to screen the mass of peptides 2) to obtain

  1. A VARIATION NORM CARLESON THEOREM RICHARD OBERLIN ANDREAS SEEGER TERENCE TAO

    E-print Network

    Seeger, Andreas

    for the Fourier series, (1) Snf(x) S[f](n, x) = n k=-n fk e2ikx ; here n N0 = {0, 1, 2, . . . }. The celebrated theorem by Carleson [4] states that if f is square integrable then Snf converges to f almost everywhere |Snf| Lp(T) C f Lp(T) for all f Lp(T); see also [10], [20], and [12] for other proofs of this fact

  2. Secure Cloud Storage Service with An Efficient DOKS Protocol ZhengTao Jiang

    E-print Network

    Liu, Ling

    some new challenges since users and cloud storage providers (either IaaS or SaaS like databases of service level agreement (SLA) with high level of guarantee. This makes security and privacy of outsourced

  3. Conductance Titration of Single-Peptide Molecules Xiaoyin Xiao, Bingqian Xu, and Nongjian Tao*

    E-print Network

    Zhang, Yanchao

    acid, cysteine, linked to a cysteamine via a peptide bond. The thiol groups in the cysteamine that it has an extra amino acid, glycine, inserted between the cysteamine and cysteine. Peptides 1 and 2, each promises a fresh approach to study various chemical processes and reactions on a single-molecule basis

  4. SoK: Eternal War in Memory Laszlo Szekeres, Mathias Payer, Tao Wei, Dawn Song

    E-print Network

    Sekar, R.

    of safety in these languages allows attackers to alter the program's behavior or take full control over written in low-level languages like C or C++ are one of the oldest problems in computer security. The lack exploits show that all currently deployed protections can be defeated. This paper sheds light

  5. Multi-Robot Collective Sorting with Local Sensing Tao Wang and Hong Zhang

    E-print Network

    Wang, Tao

    that the swarm performance is not initial configuration sensitive with our behavioral strategy for robots known. B. Related Work Distributed clustering, and more recently sorting, by a swarm of robots have served as benchmarks for swarm intelligence based robotics [3]. Deneubourg et al. conjectured in [5

  6. Kinetic instabilities in the lunar wake: ARTEMIS observations J. B. Tao,1

    E-print Network

    California at Berkeley, University of

    with little disturbance [Ness et al., 1967; Ness, 1972]. [3] The density gradient between the lunar wake and the Apollo program in the 1960s and 1970s (see Ness [1972] and Schubert and Lichtenstein [1974] for review

  7. TAO, Vol. 15, No. 4, 713-725, November 2004 NOTES AND CORRESPONDENCE

    E-print Network

    Löwemark, Ludvig

    of surface material: the refuse dump model, the cache model, and the gardening model. The detritus of the fecal material (Bromley 1991; Löwemark and Schäfer 2003). According to the refuse dump model (Fig. 2c is introduced into the burrow to buttress the cavity that is created during the feeding process (Bromley 1991

  8. An ab Mfio study of the HNCN radical F.-M. Tao and W. Klemperer

    E-print Network

    University, Cambridge, Massachusetts 02138 Michael C. McCarthy and C. A. Gottlieb Division of Applied, and Sears[J, Chem. Sot. Faraday Trans. 89, 615 ( 1993)]. The quadrupolecoupling constantsfor the inner

  9. Fabrication of magnetic microfiltration systems using soft lithography Tao Deng, Mara Prentiss,a)

    E-print Network

    Prentiss, Mara

    filtration has evolved rapidly in two areas: large-scale industrial separation,2,5,8 and biotechnology.9 to saturate these elements magnetically.8 Magnetic filtration for biotechnology has been much simpler in its in biotechnology and biology is such that the de- velopment of magnetic filters compatible with these systems would

  10. doi: 10.3319/TAO.2012.02.29.01(TT) * Corresponding author

    E-print Network

    Lee, Jian-Cheng

    of the Longitudinal Valley flat area indicates substantial subsidence of -10 to -20 mm yr-1 . Finally, it appears on interseismic deforma- tion with subsidence rate of -5 to -10 mm yr-1 . Key words: Precise leveling, GPS Taiwan is considered to be an on-land suture between these two colliding plates (Biq 1972; Ho 1975

  11. Indexing Spatio-Temporal Data Warehouses Dimitris Papadias, Yufei Tao, Panos Kalnis, and Jun Zhang

    E-print Network

    Papadias, Dimitris

    Department of Computer Science Hong Kong University of Science and Technology Clear Water Bay, Hong Kong. A vital solution is the construction of a spatiotemporal data warehouse. In this paper, we describe. As an example consider a pollution monitoring system. The readings from several sensors are fed into a database

  12. THE GREEN-TAO THEOREM ON ARITHMETIC PROGRESSIONS IN THE PRIMES: AN ERGODIC POINT OF VIEW

    Microsoft Academic Search

    BRYNA KRA

    2006-01-01

    A long-standing and almost folkloric conjecture is that the primes contain arbitrarily long arithmetic progressions. Until recently, the only prog- ress on this conjecture was due to van der Corput, who showed in 1939 that there are infinitely many triples of primes in arithmetic progression. In an amazing fusion of methods from analytic number theory and ergodic theory, Ben Green

  13. The design of the TAO real-time object request broker

    Microsoft Academic Search

    Douglas C. Schmidt; David L. Levine; Sumedh Mungee

    1998-01-01

    Many real-time application domains can benefit from flexible and open distributed architectures, such as those defined by the CORBA specification. CORBA is an architecture for distributed object computing being standardized by the OMG. Although CORBA is well-suited for conventional request\\/response applications, CORBA implementations are not yet suited for real-time applications due to the lack of key quality of service (QoS)

  14. A Real-Time Distributed Hash Table Tao Qian, Frank Mueller

    E-print Network

    Mueller, Frank

    data to a phasor data concentrator (PDC) via proprietary Internet backbones. The PDC monitors-of-art monitoring architecture uses one centralized PDC to monitor all PMUs. As the number of PMUs is increasing extremely fast nowadays, the centralized PDC will soon become a bottleneck [5]. A straight-forward solution

  15. Self-adaptive Cloud Capacity Planning Yexi Jiang, Chang-shing Perng, Tao Li, Rong Chang

    E-print Network

    Li, Tao

    , taoli}@cs.fiu.edu IBM T.J Watson Research Center, Hawthorne, NY, 10532 Email: {perng, rong}@us. On one hand, underestimation of the cloud capacity can cause resource shortage and revenue loss the potential revenue. If the shortage is severe, even provisioning requests from existing customers have

  16. Intelligent Cloud Capacity Management Yexi Jiang, Chang-Shing Perng, Tao Li, Rong Chang

    E-print Network

    Li, Tao

    , taoli}@cs.fiu.edu IBM T.J Watson Research Center, Hawthorne, NY, 10532 Email: {perng, chang}@us has to turn down new customers and lose potential revenue. If the shortage is severe, even, cooling systems, power systems, etc.), and utility (electricity and water). Among these factors, power

  17. Integrated Droplet Routing in the Synthesis of Microfluidic Tao Xu and Krishnendu Chakrabarty

    E-print Network

    Chakrabarty, Krishnendu

    for enzymatic assays to detect glucose and lactate levels in blood [3], detection of explosives such as TNT [4-throughput sequencing, parallel immunoassays, blood chemistry for clinical diagnostics, DNA sequencing, whereby groups of unit cells in a microfluidic array can be reconfigured to change their functionality

  18. A Model-based Front-end to TAO\\/ACE: The Embedded System Modeling Language

    Microsoft Academic Search

    Gabor Karsai; Sandeep Neema; Arpad Bakay; Akos Ledeczi; Feng Shi; Andy Gokhale

    2002-01-01

    The development of embedded systems necessitates the use of models throughout the engineering process that allow both the analysis and synthesis of the system. This paper introduces a system-level modeling language, which uses a specific, well-defined component model and model of computation, supported by an existing run-time infrastructure. The language allows component modeling, interaction modeling, and configuration modeling. The language

  19. doi: 10.3319/TAO.2010.05.19.01(TibXS) * Corresponding author

    E-print Network

    Hwang, Cheinway

    and Matsuyama 2006). The Kazakh upland to its north has a semi-arid climate. The Saryesik-Atryan desert lies with a low over the Tian Shan and a high over western Lake Baikal. Due to the climates over the two lakes Baikal is located in Siberia and it has an extreme continental climate with a long, very cold and dry

  20. Quantifying Contextual Information for Object Detection Wei-Shi Zheng, Shaogang Gong and Tao Xiang

    E-print Network

    Gong, Shaogang

    con- textual information that is relevant to object detection is utilised. Experiments on PASCAL VOC2005 and i-LIDS datasets demonstrate that the proposed context modelling approach improves object of contextual information, our polar context descriptor offers greater flexibility in capturing different types

  1. TAO ET AL. VOL. 6 ' NO. 3 ' 23192325 ' 2012 www.acsnano.org

    E-print Network

    progress in the synthesis of large area single and few layer graphene1Ã?4 has enabled study of various- taxial growth of graphene on single crystal Cu (111), but with a large defect-peak and small domains Chemical Society Synthesis of High Quality Monolayer Graphene at Reduced Temperature on Hydrogen

  2. Improving Wireless Security Through Network Tao Ye, Darryl Veitch, Jean Bolot

    E-print Network

    of our model in the wiretap channel framework of in- formation theory and characterize the secrecy, that are critical to companies, governments, families and in- dividual users. Critical services are valuable

  3. Security and Surveillance Shaogang Gong and Chen Change Loy and Tao Xiang

    E-print Network

    Gong, Shaogang

    automatically human activity and detect unusual events that could pose a threat to public security and safety. 1 years, largely in response to rising anxieties about crime and its threat to security and safety-assisted and automated model. In the following, we describe applications and the latest advances in automated visual

  4. Geologic map of the Ojo Caliente Quadrangle, Rio Arriba and Taos Counties, New Mexico

    SciTech Connect

    Stix, J. (comp.)

    1986-11-01

    The Ojo Caliente area forms part of the western limb of the Espanola basin within the Rio Grande rift of northern New Mexico (Manley, 1979; May, 1979). The geology consists of Miocene basin-fill sedimentary rocks that rest unconformably on, or are faulted against, Proterozoic crystalline metamorphic rocks. The Miocene rocks dip gently to the southeast, except where the attitudes are controlled by faulting or by the underlying basement topography. The Precambrian and Miocene rocks are unconformably overlain by Quaternary pediment and river gravels, loess, travertine, landslide debris, and alluvium. The Precambrian rocks are faulted into horsts in several areas by north - northeast - trending normal faults.

  5. Design-for-Testability for Digital Microfluidic Biochips* Tao Xu and Krishnendu Chakrabarty

    E-print Network

    Chakrabarty, Krishnendu

    in etched microchannels [2]. Some recent continuous-flow biochip products include the TopazTM system protocols (in terms of liquid volumes and assay times) are mapped and executed on a microfluidic chip

  6. Collaborative Annotation of Real Time Streams on Android-Enabled Devices Tao Huang, Geoffrey Fox

    E-print Network

    and ease of use, mobile software/hardware products are drawing attentions of the major internet population will be the next burst of Internet growth. Besides the great interest from the industry, mobile platforms also {taohuang, gcf}@indiana.edu ABSTRACT Mobile based collaboration such as image tagging and video annotation

  7. A Simulation Tool for Evaluating Shared Memory Systems Jie Tao 1 , Martin Schulz 2 , and Wolfgang Karl 1

    E-print Network

    Stamatakis, Alexandros

    toolkit for Intel architectures, SIMT focuses on the memory hierarchy and contains facilities models multilevel cache hierarchies with several cache coherence protocols; a distributed memory at any level of the memory hierarchy, allowing an acquisition of comprehensive monitoring information

  8. On Efficient Spatial Matching Raymond Chi-Wing Wong Yufei Tao Ada Wai-Chee Fu Xiaokui Xiao

    E-print Network

    Wong, Raymond Chi-Wing

    places p1, p2, p3 and O includes three residential estates o1, o2, o3. Assume that we want to decide.e., the BRNN set of p1 is {o1, o2, o3}), while p2 and p3 serve no estate at all. This assignment of polling-1-59593-649-3/07/09. o1 o2 o3 p1 p2 p3 Estate o1 o2 o3 Population 7k 3k 4k Poll. place p1 p2 p3 Capacity 10k 10k 10k (a

  9. TAO, Vol. 10, No. 4, 719-736, December 1999 Development of an Integrated Earthquake Early Warning System in

    E-print Network

    Wu, Yih-Min

    of 8 strong-motion stations was installed in Hualien area for testing earthquake early warning the Philippine Sea plate off the southern tip of Taiwan. Most of Taiwan is under NW-SE compression that shear waves will take more than 30 sec to reach Taipei

  10. An Analytical Model for a Book-ahead Bandwidth Xiangfei Zhu, Mark E. McGinley, Tao Li, Malathi Veeraraghavan

    E-print Network

    Veeraraghavan, Malathi

    -loop control of the equipment, and video monitoring of the experiment. To meet the needs of these scientists into inter- vals. Our proposed model is a non-homogeneous continuous-time Markov chain, which has an embedded utilization. This model can be used by network designers to select the size of the reservation window, K

  11. Learning High-Level Planning from Text S.R.K. Branavan, Nate Kushman, Tao Lei, Regina Barzilay

    E-print Network

    Barzilay, Regina

    to create high-level plans based on language ab- stractions. Our model jointly learns to predict be made from wood. (a) Low Level Actions for: wood pickaxe stone step 1: move from (0,0) to (2,0) step 2: chop tree at: (2,0) step 3: get wood at: (2,0) step 4: craft plank from wood step 5: craft stick from

  12. Two-Dimensional Photonic Crystal Surfactant Detection Jian-Tao Zhang, Natasha Smith, and Sanford A. Asher*

    E-print Network

    Asher, Sanford A.

    . Asher* Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States and detergents and in cosmetics, industrial cleaners, etc.1 These applications result in release

  13. TAO, Vol. 15, No. 3, 545-562, September 2004 Preliminary Results of the iSTEP Program on Integrated

    E-print Network

    Chen, Yuh-Ing

    at identifying potential seismological, geomagnetic, geodetic and ionospheric precursors, and sta- tistical preliminary results have been obtained. These includes precursory P wave travel-time changes six years before ionospheric anomalies three days before M 5 earthquakes. We have also developed high-resolution radar inter

  14. Online Spatial Data Analysis and Visualization System Yun Lu, Mingjin Zhang, Tao Li, Yudong Guang, Naphtali Rishe

    E-print Network

    Li, Tao

    services on traditional computing platforms as well as the emerging mobile devices. However, due, Naphtali Rishe School of Computing and Information Sciences Florida International University, Miami System (GIS) applications. The Web can provide a giant amount of information to a multitude of users

  15. WHYPER: Towards Automating Risk Assessment of Mobile Applications Rahul Pandita, Xusheng Xiao, Wei Yang, William Enck, Tao Xie

    E-print Network

    Xie, Tao

    malware. To address market-security issues, the two predom- inant smartphone platforms (Apple and Google have played an important role in the popularity of smartphones and mobile devices. However, keeping malware out of application markets is an ongo- ing challenge. While recent work has developed various

  16. Physics 611 Course Outline Instructor: Prof. Tao Zhou, taozhou@njit.edu, Tel: 973-642-4931, Room: T478

    E-print Network

    mechanics. Detailed knowledge of canonical transformation and Hamilton-Jacobi equation will help students Poisson bracket methods · Using Hamilton-Jacobi equation to solve various mechanic problems, in particular

  17. TAO, Vol. 16, No. 5, 1097-1120, December 2005 Characteristic Trace Fossils from Shoreface to Offshore Environments

    E-print Network

    Chen, Wen-Shan

    sea level. The Upper Oli- gocene deposits show a shallowing-upward succession that suggests an evo to Offshore Environments of an Oligocene Succession, Northeastern Taiwan Wen-Shan Chen 1, * (Manuscript. The Oligocene succession records a deepening-upward to shallowing-upward sequence of deltaic deposystems

  18. Academic Administration and Management Scenarios on the Semantic Web Feng (Barry) Tao, Shakeel A. Khoja, Hugh Davis, Andy Gravell

    E-print Network

    Gravell, Andrew M.

    , University of Southampton, Southampton, U.K. {ft, sk07v, hcd, amg}@ecs.soton.ac.uk #12;Abstract This paper) [3,4] are used to provide educational services, such as Virtual Learning Environments (VLEs), course for educational materials using its well established EPrints research repository software [9] as the framework. Ed

  19. TAO, Vol. 11, No. 4, 753-764, December 2000 A Rapid Method for the Determination of 137

    E-print Network

    Huh, Chih-An

    - ronments from atomic bomb tests, nuclear accidents, and nuclear waste disposal. As an ele- ment of the Cs can be determined by atomic absorption spectrometry or by gravimetric measurement of H2 PtCl6

  20. High-density organic light emitting diodes by nanoimprint technology Krutarth Trivedi, Caleb Nelson, Li Tao, Mathew Goeckner, Walter Hua)

    E-print Network

    Hu, Wenchuang "Walter"

    High-density organic light emitting diodes by nanoimprint technology Krutarth Trivedi, Caleb Nelson sources. Despite the considerable development of inorganic semiconductor based light emitting diodes of miniaturization to nanoscale. Organic light emitting diode (OLED) technology is immune to quantum confinement

  1. Control of a model of DNA division via parametric resonance Wang Sang Koon, Houman Owhadi, Molei Tao, and Tomohiro Yanao

    E-print Network

    Koon, Wang Sang

    - magnetic fields for triggering and controlling the division. The suggested method of control is supported-channel matrices J. Appl. Phys. 113, 024701 (2013) Cooperativity in the annealing of DNA origamis JCP: Bio that it is sensitive to specific fine scale modes and frequencies that could be targeted by low intensity electro-magnetic

  2. Geopolitics of Quantum Buddhism: Our Pre-Hydrocarbon Tao Future (No Breakthrough at the Rio+20 Summit)

    ERIC Educational Resources Information Center

    Bajrektarevic, Anis

    2013-01-01

    From Rio to Rio with Kyoto, Copenhagen and Durban in between, the conclusion remains the same: we fundamentally disagree on realities of this planet and the ways we can address them. A decisive breakthrough would necessitate both wider contexts and a larger participatory base so as to identify problems, formulate policies, and broaden and…

  3. Multifunctional organic phototransistor-based nonvolatile memory achieved by UV/ozone treatment of the Ta?O? gate dielectric.

    PubMed

    Liu, Xiaohui; Zhao, Haoyan; Dong, Guifang; Duan, Lian; Li, Dong; Wang, Liduo; Qiu, Yong

    2014-06-11

    An organic phototransistor (OPT) shows nonvolatile memory effect due to its novel optical writing and electrical erasing processes. In this work, we utilize an organic light-emitting diode (OLED) as the light source to investigate OPT-based memory (OPTM) performance. It is found that the OPTM can be used as either flash memory or write-once read-many-times memory by adjusting the properties of the Ta2O5 gate dielectric layer. UV/ozone treatment is applied to effectively change dielectric properties of the Ta2O5 film. The mechanisms for this are examined by X-ray photoelectron spectroscopy and capacitance-voltage measurement. It turns out that the densities of oxygen vacancies and defects in the first 1.8 nm Ta2O5 films near the Ta2O5/semiconductor interface are reduced. Furthermore, for the first time, we use this multifunctional OPTM, which unites the photosensitive and memory properties in one single device, as an optical feedback system to tune the brightness of the OLED. Our study suggests that these OPTMs have potential applications in tuning the brightness uniformity, improving the display quality and prolonging the lifetime of flat panel displays. PMID:24813352

  4. Estimating Phosphorous Load from a Large Watershed in the Great Lakes Basin Weichun Tao, Carlo DeMarchi,

    E-print Network

    generation and transport models is the best response to this challenge, yet it is a complex and time to quantify watershed nutrient loads include estimating the annual or seasonal loads using simple relations when based on typically infrequent routine monitoring data. The second approach may produce more

  5. TAO, Vol. 13, No. 3, 313-324, September 2002 Near Real-Time Seismic Damage Assessment of

    E-print Network

    Wu, Yih-Min

    Reporting System Yih-Min Wu 1, *, Nai-Chi Hsiao 1 , Ta-Liang Teng 2 , and Tzay-Chyn Shin 1 (Manuscript collapsing rates) during the 1999 Chi-Chi earthquake were determined in this study. The distribution-motion accelerograph network consisting 82 stations distributed around Tai- wan were established by the Central Weather

  6. 77 FR 37941 - Order Granting a Limited Exemption From Exchange Act Rule 10b-17 to Certain Actively Managed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-25

    ...g., Letter from Josephine J. Tao, Assistant Director to W. John McGuire, Esq., Morgan...2011); Letter from Josephine J. Tao, Assistant Director to Jeremy Senderowicz...and Letter from Josephine J. Tao, Assistant Director to Jack...

  7. Disturbances of Modulating Molecules (FOXP3, CTLA-4/CD28/B7, and CD40/CD40L) mRNA Expressions in the Orbital Tissue from Patients with Severe Graves' Ophthalmopathy

    PubMed Central

    Pawlowski, Przemyslaw; Eckstein, Anja; Luczynski, Wlodzimierz; Johnson, Kristian; Kretowski, Adam; Bakunowicz-Lazarczyk, Alina; Gorska, Maria; Szamatowicz, Jacek; Chyczewski, Lech; Mysliwiec, Janusz

    2015-01-01

    Purpose. To evaluate the relationship between the expression of orbital tissue mRNA for FOXP3, CTLA-4/CD28/CD80/CD86, and CD40/CD40 and the severity of Graves' orbitopathy (GO). Material and Methods. Orbital tissue was obtained from 26 patients with GO, with mild (n = 6) or severe GO (n = 20), and 7 healthy controls. The expression of mRNA of FOXP3, CTLA-4/CD28/CD80/CD86, CD40/CD40L was measured by RT-PCR. TCR and CD3 were evaluated by immunohistochemistry. Results. Higher mRNA for FoxP3 (relative expression: 1.4) and CD40 (1.27) and lower expression of CTLA-4 (0.61) were found in the GO tissues versus controls. In severe GO as compared to mild GO higher mRNA expression for FoxP3 (1.35) and CD40 (1.4) and lower expression for CTLA-4 (0.78), CD28 (0.62), and CD40L (0.56) were found. A positive correlation was found between FOXP3 mRNA and CD3 infiltration (R = 0.796, P = 0.0000001). Conclusions. The enhanced FOXP3 mRNA expression in GO samples may suggest the dysfunction of FOXP3 cells in the severe GO. The diminished mRNA expression of CTLA-4 in severe GO may indicate inadequate T regulatory function. The enhanced mRNA expression of CD40 in severe GO and negative correlation to CRP mRNA may suggest their role in the active and inactive GO. PMID:25653477

  8. EXAFS structure refinement supplemented by computational chemistry Ya-Wen Hsiao,1 Ye Tao,2 Jacob E. Shokes,2 Robert A. Scott,2 and Ulf Ryde1,

    E-print Network

    Scott, Robert A.

    in standard crystallographic or NMR structure refine- ment. In addition, the method provides structures- lem although much less severe is encountered in both x-ray crystallography and NMR structure . In these techniques, the problem is solved by supplementing the experimental data with chemical

  9. Sub-50 nm scratch-proof DLC molds for reversal nanoimprint lithography L. Tao, C. T. Nelson, K. Trivedi, S. Ramachandran, M. Goeckner, L. Overzet, and Walter Hua)

    E-print Network

    Hu, Wenchuang "Walter"

    and reversal nanoimprint in SU-8. We observed a problem of mold bending in conventional nanoimprint if "female-uniform imprinted structures, particularly non-uniform residue layer. As shown in Fig. 1a, when a "thin" female mold work [1]. Fig. 3 and Fig. 4a shows SEM images of the mold with structures of 200 nm and 40 nm

  10. Novel type of chimera spiral waves arising from decoupling of a diffusible component Xiaodong Tang, Tao Yang, Irving R. Epstein, Yang Liu, Yuemin Zhao, and Qingyu Gao

    E-print Network

    Epstein, Irving R.

    Novel type of chimera spiral waves arising from decoupling of a diffusible component Xiaodong Tang (2014) Novel type of chimera spiral waves arising from decoupling of a diffusible component Xiaodong in chimera spirals grows drastically, leading to modulation and breakup of the spirals, in the transition

  11. Digital data from the Questa-San Luis and Santa Fe East helicopter magnetic surveys in Santa Fe and Taos Counties, New Mexico, and Costilla County, Colorado

    USGS Publications Warehouse

    Bankey, Viki; Grauch, V.J.S.; Drenth, B.J.; Geophex Ltd.

    2006-01-01

    This report contains digital data, image files, and text files describing data formats and survey procedures for aeromagnetic data collected during high-resolution aeromagnetic surveys in southern Colorado and northern New Mexico in December, 2005. One survey covers the eastern edge of the San Luis basin, including the towns of Questa, New Mexico and San Luis, Colorado. A second survey covers the mountain front east of Santa Fe, New Mexico, including the town of Chimayo and portions of the Pueblos of Tesuque and Nambe. Several derivative products from these data are also presented as grids and images, including reduced-to-pole data and data continued to a reference surface. Images are presented in various formats and are intended to be used as input to geographic information systems, standard graphics software, or map plotting packages.

  12. Quantifying the `reverse water gas shift' reaction inside a PEM fuel cell Tao Gu, W.-K. Lee, J.W. Van Zee*

    E-print Network

    Van Zee, John W.

    membrane fuel cells (PEMFCs), and recent evidence has shown that CO2 can react in situ with H2 (i composition, and temperature affect this reaction in a PEMFC for both Pt and Pt/Ru alloy catalysts (PEMFC); Reformate; Reverse water gas shift (RWGS) reaction; CO stripping; Pressure and temperature

  13. Beale&PollackUSQRPaperOctober2010(rev13Sept10) Page1 The Great Commandment, Tao, and the Survival of Humanity

    E-print Network

    Pollack, Robert

    of Archimedes, technological and scientific progress have been intimately linked with warfare. This reached an apotheosis with the development of nuclear weapons, which gave human beings for the first time a technology questionable. It used to be asserted that a full-scale nuclear war might eliminate life on earth. However what

  14. Current trends in the management of Graves' disease

    Microsoft Academic Search

    B. Solomon; D. Glinoer; R. Lagasse; L. Wartofsky

    1990-01-01

    Members of the American Thyroid Association were invited to participate in a survey of the management of Graves' disease. One primary case and several variations were provided, which differed in respect to age, sex, goiter size, severity, etc. The questionnaire was based on the format used in a similar survey of members of the European Thyroid Association. The aim of

  15. This is a free offprint provided to the author by the publisher. Copyright restrictions may apply. Contemporary Mathematics

    E-print Network

    Arbogast, Todd

    methods for heterogeneous elliptic problems Todd Arbogast, Zhen Tao, and Hailong Xiao Abstract. Consider restrictions may apply. 10 TODD ARBOGAST, ZHEN TAO, AND HAILONG XIAO where Rd , d = 2 or 3, is the problem

  16. UNIVERSITE PARIS DESCARTES ECOLE DOCTORALE 420 DE SANTE PUBLIQUE

    E-print Network

    Paris-Sud XI, Université de

    : le trastuzumab, anticorps monoclonal administré par voie intraveineuse et le lapatinib, inhibiteur de TAO. Un modèle comparant le coût du traitement intraveineux (trastuzumab) aux TAO (lapatinib et

  17. A SUPERSYMMETRIC VIEW OF THE HIGGS HUNTING

    E-print Network

    Fygenson, Deborah Kuchnir

    A SUPERSYMMETRIC VIEW OF THE HIGGS HUNTING Tao Liu UC @ Santa Barbara UC @ Santa Barbara Feb. 2nd, 2011 Thursday, February 2, 2012 #12;Tao Liu (UC@Santa Barbara) Hunting for the Higgs 2 Higgs Boson) Thursday, February 2, 2012 #12;Tao Liu (UC@Santa Barbara) Hunting for the Higgs 3 ! At hadron colliders

  18. 17. Photocopy of architectural drawing (from Albuquerque Area Indian Health ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. Photocopy of architectural drawing (from Albuquerque Area Indian Health Service, Division of Health Facilities, Albuquerque, New Mexico) Mayers, Murray, and Phillip, Architects, New York, NY, 1934 Elevations - Taos Indian Health Center, 0.3 mile south-southwest of Pueblos Plaza, Taos Pueblo, Taos County, NM

  19. 18. Photocopy of architectural drawing (from Albuquerque Area Indian Health ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Photocopy of architectural drawing (from Albuquerque Area Indian Health Service, Division of Health Facilities, Albuquerque, New Mexico) Mayers, Murray, and Phillip, Architects, New York, NY, 1934 Detail sheet - Taos Indian Health Center, 0.3 mile south-southwest of Pueblos Plaza, Taos Pueblo, Taos County, NM

  20. 16 Photocopy of architectural drawing (from Albuquerque Area Indian Health ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16 Photocopy of architectural drawing (from Albuquerque Area Indian Health Service, Division of Health Facilities, Albuquerque, New Mexico) Mayers Murray, and Phillip, Architects, New York, NY, 1934 first floor mechanical plan - heating - Taos Indian Health Center, 0.3 mile south-southwest of Pueblos Plaza, Taos Pueblo, Taos County, NM

  1. 14. Photocopy of architectural drawing (from Albuquerque Area Indian Health ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photocopy of architectural drawing (from Albuquerque Area Indian Health Service, Division of Health Facilities, Albuquerque, New Mexico) Mayers, Murray, and Phillip, Architects, New York, N&, 1934 Foundation Plan - Taos Indian Health Center, 0.3 mile south-southwest of Pueblos Plaza, Taos Pueblo, Taos County, NM

  2. 15. Photocopy of architectural drawing (from Albuquerque Area Indian Health ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Photocopy of architectural drawing (from Albuquerque Area Indian Health Service, Division of Health Facilities, Albuquerque, New Mexico) Mayers, Murray, and Phillip, Architects, New York, NY, 1934 First Floor - plumbing - Taos Indian Health Center, 0.3 mile south-southwest of Pueblos Plaza, Taos Pueblo, Taos County, NM

  3. Study Questions Close Monitoring of Thyroid Growths

    MedlinePLUS

    ... Anne Cappola, an endocrinologist at the University of Pennsylvania. Because of that, thyroid association guidelines say that ... D., Sc.M., associate professor, medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia; Hossein Gharib, M. ...

  4. Questa Baseline and Pre-Mining Ground-Water Quality Investigation. 24. Seismic Refraction Tomography for Volume Analysis of Saturated Alluvium in the Straight Creek Drainage and Its Confluence With Red River, Taos County, New Mexico

    USGS Publications Warehouse

    Powers, Michael H.; Burton, Bethany L.

    2007-01-01

    As part of a research effort directed by the New Mexico Environment Department to determine pre-mining water quality of the Red River at a molybdenum mining site in northern New Mexico, we used seismic refraction tomography to create subsurface compressional-wave velocity images along six lines that crossed the Straight Creek drainage and three that crossed the valley of Red River. Field work was performed in June 2002 (lines 1-4) and September 2003 (lines 5-9). We interpreted the images to determine depths to the water table and to the top of bedrock. Depths to water and bedrock in boreholes near the lines correlate well with our interpretations based on seismic data. In general, the images suggest that the alluvium in this area has a trapezoidal cross section. Using a U.S. Geological Survey digital elevation model grid of surface elevations of this region and the interpreted elevations to water table and bedrock obtained from the seismic data, we generated new models of the shape of the buried bedrock surface and the water table through surface interpolation and extrapolation. Then, using elevation differences between the two grids, we calculated volumes of dry and wet alluvium in the two drainages. The Red River alluvium is about 51 percent saturated, whereas the much smaller volume of alluvium in the tributary Straight Creek is only about 18 percent saturated. When combined with average ground-water velocity values, the information we present can be used to determine discharge of Straight Creek into Red River relative to the total discharge of Red River moving past Straight Creek. This information will contribute to more accurate models of ground-water flow, which are needed to determine the pre-mining water quality in the Red River.

  5. A-SITE-AND/OR B-SITE-MODIFIED PBZRTIO3 MATERIALS AND (PB, SR, CA, BA, MG) (ZR, TI,NB, TA)O3 FILMS HAVING UTILITY IN FERROELECTRIC RANDOM ACCESS MEMORIES AND HIGH PERFORMANCE THIN FILM MICROACTUATORS

    NASA Technical Reports Server (NTRS)

    Roeder, Jeffrey F. (Inventor); Chen, Ing-Shin (Inventor); Bilodeau, Steven (Inventor); Baum, Thomas H. (Inventor)

    2004-01-01

    A modified PbZrTiO.sub.3 perovskite crystal material thin film, wherein the PbZrTiO.sub.3 perovskite crystal material includes crystal lattice A-sites and B-sites at least one of which is modified by the presence of a substituent selected from the group consisting of (i) A-site substituents consisting of Sr, Ca, Ba and Mg, and (ii) B-site substituents selected from the group consisting of Nb and Ta. The perovskite crystal thin film material may be formed by liquid delivery MOCVD from metalorganic precursors of the metal components of the thin film, to form PZT and PSZT, and other piezoelectric and ferroelectric thin film materials. The thin films of the invention have utility in non-volatile ferroelectric memory devices (NV-FeRAMs), and in microelectromechanical systems (MEMS) as sensor and/or actuator elements, e.g., high speed digital system actuators requiring low input power levels.

  6. Adler, R. F., H.-Y. M. Yeh, N. Prasad, W.-K. Tao, and J. Simpson, 1991: Microwave simulations of a tropical rainfall system with a three-dimensional cloud model. J.

    E-print Network

    Jiang, Haiyan

    ., 56, 852-867. Bell, T. L. 1987: A space-time stochastic model of rainfall for satellite remote. Atmos. Sci., 53, 1887-1909. Black, P.G., and C. T. Swift, 1984: Airborne stepped frequency microwave. J., E. J. Zipser, 1999: Relationships between tropical cyclone intensity and satellite

  7. CSC458/CSC2209 Final Project Description/Documentation Michael Tao In order to allow users to persistently share mutable media between both themselves and others, the ability to

    E-print Network

    Toronto, University of

    current copies of content over several electronic devices has become a must. True transparency, however a decentralized Dropbox: users identify directories that they want to be maanged across several electronic devices the directory, including its children directories, in such a way that would both allow for the distribution

  8. Interaction of Ta-O and perpendicular magnetic anisotropy of Ta/Pd (0-2.4 nm)/Co2FeAl0.5Si0.5/MgO/Ta structured films

    NASA Astrophysics Data System (ADS)

    You, C. Y.; Fu, H. R.; Zhang, X.; Tian, N.; Wang, P. W.

    2015-03-01

    Perpendicular magnetic anisotropy (PMA) was realized by inserting Pd layer into the stack of Ta/Pd (0-2.4 nm)/Co2FeAl0.5Si0.5/MgO/Ta. The realization of PMA is accompanied by the (Co, Fe)-O reduction at Co2FeAl0.5Si0.5/MgO interface under annealing. Without inserting Pd layer, the annealed Ta/Co2FeAl0.5Si0.5/MgO/Ta film presents an in-plane magnetization. Through X-ray photoelectron spectrometry analyzes, it was found that the oxygen was enriched at the interface of Ta/Co2FeAl0.5Si0.5. This work clarifies that the inserted Pd layer effectively blocks the diffusion of interfacial oxygen to Ta layer, achieving the beneficial redox reaction at Co2FeAl0.5Si0.5/MgO interface to realize PMA.

  9. Tao, M., Conway, R., Cheta, S., Chiang, H.-C., & Yan, T.-F. Tyler, J. M., Reinhardt, B. N., & Branton, D. (1980) J. Biol. (1981) Cold Spring Harbor Conf. Cell Proliferation 8,

    E-print Network

    of the Voltage-Dependent Regulatory (Inhibitory) Site for Acetylcholine in Membrane Vesicles from Torpedo was obtained in membrane vesicles prepared from the Torpedo californica electric organ. Two rate coefficients

  10. Treatment of antipsychotic-associated obesity with a GLP-1 receptor agonist—protocol for an investigator-initiated prospective, randomised, placebo-controlled, double-blinded intervention study: the TAO study protocol

    PubMed Central

    Ishøy, Pelle L; Knop, Filip K; Broberg, Brian V; Baandrup, Lone; Fagerlund, Birgitte; Jørgensen, Niklas R; Andersen, Ulrik B; Rostrup, Egill; Glenthøj, Birte Y; Ebdrup, Bjørn H

    2014-01-01

    Introduction Antipsychotic medication is widely associated with dysmetabolism including obesity and type 2 diabetes, cardiovascular-related diseases and early death. Obesity is considered the single most important risk factor for cardiovascular morbidity and mortality. Interventions against antipsychotic-associated obesity are limited and insufficient. Glucagon-like peptide-1 (GLP-1) receptor agonists are approved for the treatment of type 2 diabetes, but their bodyweight-lowering effects have also been recognised in patients with non-diabetes. The primary endpoint of this trial is weight loss after 3?months of treatment with a GLP-1 receptor agonist (exenatide once weekly) in patients with non-diabetic schizophrenia with antipsychotic-associated obesity. Secondary endpoints include physiological and metabolic measurements, various psychopathological and cognitive measures, and structural and functional brain MRI. Methods and analysis 40 obese patients with schizophrenia or schizoaffective disorder treated with antipsychotic drugs will be randomised to subcutaneous injection of exenatide once weekly (2?mg) or placebo for 3?months, adjunctive to their antipsychotic treatment. Ethics and dissemination The trial has been approved by the Danish Health and Medicines Authority, the National Committee on Health Research Ethics and the Danish Data Protection Agency. Trial participation presupposes theoral and written patient informed consent. An external, independent monitoring committee (Good Clinical Practice Unit at Copenhagen University Hospital) will monitor the study according to the GCP Guidelines. Trial data, including positive, negative and inconclusive results, will be presented at national and international scientific meetings and conferences. Papers will be submitted to peer-reviewed journals. Trial registration ClinicalTrials.gov identifier: NCT01794429; National Committee on Health Research Ethics project number: 36378; EudraCT nr: 2012-005404-17; The Danish Data Protection Agency project number: RHP-2012-027. PMID:24401727

  11. Characterization of a Self-sufficient Trans-Anethole Oxygenase from Pseudomonas putida JYR-1

    PubMed Central

    Han, Dongfei; Sadowsky, Michael J.; Chong, Youhoon; Hur, Hor-Gil

    2013-01-01

    A novel flavoprotein monooxygenase, trans-anethole oxygenase (TAO), from Pseudomonas putida JYR-1, which is capable of catalyzing the oxidation of trans-anethole to p-anisaldehyde, was heterologously expressed in E. coli and purified. Enzymatic kinetics of diverse substrates and cofactors revealed that TAO is likely to be a novel self-sufficient flavoprotein monooxygenase. Enzyme assays of GST-TAO demonstrated that TAO catalyzed a trans-anethole oxidation reaction without auxiliary component enzyme-like electron-transfer flavin reductases. The single component TAO had the ability to reduce flavin cofactors and simultaneously oxidize trans-anthole to p-anisaldehyde. In the processes of reduction of flavin and oxidation of trans-anethole, TAO accepted various flavin and NAD(P)H cofactors. TAO also catalyzed oxidation of isoeugenol, O-methyl isoeugenol, and isosafrole, all of which contain the 2-propenyl functional group on the aromatic ring structure with different catalytic efficiency. TAO had the greatest catalytic efficiency (kcat/Km) with the original substrate, trans-anethole. Investigation about partially deleted mutants of TAO indicated that reductase active sites appeared to be located near the N terminal. Site directed mutagenesis studies also proved that the proposed flavin binding sites, Trp-38, Thr-43, Tyr-55, were critical for flavin reduction. However, disruption of any portion of TAO eliminated the oxygenase activity. PMID:24066043

  12. Radiation retinopathy

    SciTech Connect

    Parker, R.G.; Withers, H.R.

    1988-01-01

    A letter to the editor discusses the effectiveness and risk of radiation treatment of Grave's ophthalmopathy. The authors are unable to document a single instance in which retinopathy can be attributed to therapy with a total dose of 2000 cGy when delivered in daily increments of 180 to 200 cGy.

  13. Smoking and thyroid disorders--a meta-analysis

    Microsoft Academic Search

    Peter Vestergaard

    2002-01-01

    Background: Smoking has been associated with Graves' disease, but it remains unclear if the association is present in other thyroid disorders. Outcome variables: Graves' disease, Graves' ophthalmopathy, toxic nodular goitre, non-toxic goitre, post-partum thyroid disease, Hashimoto's thyroiditis, or hypothyroidism. Material and methods: A search of MEDLINE identified 25 studies on the association between smoking and thyroid diseases. Results: In Graves'

  14. GRONDSLAGEN VAN HET TAOÏSTISCHE DENKEN

    Microsoft Academic Search

    U. J. Libbrecht

    1995-01-01

    Tao, the ‘Way’, the dynamic principle of the universe, can only operate within a ch’ispace, i.e., an energetic space, or a universe of becoming. This becoming is a non-chaotic process — fact that is expressed in the tao-metaphor. Tao is not an autonomous transcendent principle, but is immanent to the universe, which is by itself creative. In this organic cosmos,

  15. Thermal Acoustic Oscillation: Causes, Detection, Analysis, and Prevention

    NASA Technical Reports Server (NTRS)

    Christie, R. J.; Hartwig, J. W.

    2014-01-01

    Thermal Acoustic Oscillations (TAO) can occur in cryogenic systems and produce significant sources of heat. This source of heat can increase the boil off rate of cryogenic propellants in spacecraft storage tanks and reduce mission life. This paper discusses the causes of TAO, how it can be detected, what analyses can be done to predict it, and how to prevent it from occurring.The paper provides practical insight into what can aggravate instability, practical methods for mitigation, and when TAO does not occur. A real life example of a cryogenic system with an unexpected heat source is discussed, along with how TAO was confirmed and eliminated.

  16. The number of plants in New Mexico..............1

    E-print Network

    Johnson, Eric E.

    Cruces, NM 88003] Helictotrichon hookeri (Scribner) Henrard (Gramineae): Taos Co.: Carson National Forest this species as Avenula hookeri (Scribner) Holub.] Panicum alatum Zuloaga & Morrone var. alatum

  17. Activation of cytokines corroborate with development of inflammation and autoimmunity in thromboangiitis obliterans patients.

    PubMed

    Dellalibera-Joviliano, R; Joviliano, E E; Silva, J S; Evora, P R B

    2012-10-01

    Thromboangiitis obliterans (TAO) is a segmental inflammatory occlusive disorder that affects the arm and leg arteries of young smokers. The immune system seems to play a critical role in the aetiology of TAO; however, knowledge of the aspects involved in the progression of vascular tissue inflammation and, consequently, the evolution of this disease is still limited. This study was carried out to investigate the cytokine levels of tumour necrosis factor (TNF)-?, interleukin (IL)-1?, IL-4, IL-17 and IL-23 in the plasma of TAO patients presenting with acute clinical manifestations. The study included 20 TAO patients (n = 10 women; n = 10 men) aged 38-59 years under clinical follow-up, classified into two groups: (i) TAO former smokers (n = 11) and (ii) TAO active smokers (n = 9); the control groups included normal volunteer non-smokers (n = 10, active smokers (n = 10) and former smokers (n = 10). Patients' plasma samples were measured using the sandwich enzyme-linked immunosorbent assay. Statistical analyses were performed using the non-parametric Mann-Whitney U-test, with parameters significant at P < 0·05. The activities of all cytokines were different in groups of TAO patients when compared with normal controls, and decreased for control smokers. Increased levels of TNF-?, IL-1?, IL-4, IL-17 and IL-23 were significant in patients with TAO when compared to the controls (P < 0·005, all parameters). The results presented here indicate an increased production of cytokines in TAO, possibly contributing to the inflammatory response observed in the patients' vascular levels. In addition, the increased levels of IL-17 and IL-23 suggest that the disturbance of TAO is involved with mechanisms of autoimmunity. Thus, the discovery of IL-17 and its association with inflammation and autoimmune pathology has reshaped our viewpoint regarding the pathogenesis of TAO, which was based previously on the T helper type 1 (Th1)-Th2 paradigm. PMID:22943198

  18. Stark spectroscopy on rare gas atoms

    E-print Network

    Eindhoven, Technische Universiteit

    Stark spectroscopy on rare gas atoms PROEFSCHRIFT ter verkrijging van de graad van doctor aan de-DATA LIBRARY TECHNISCHE UNIVERSITEIT EINDHOVEN Jiang, Tao Stark spectroscopy on rare gas atoms / by Tao Jiang / gasontladingen Subject headings : plasma diagnostics / Stark effect / optogalvanic spectroscopy / atomic emission

  19. ASPIDISTRA (ASPARAGACEAE S.L., ASPARAGALES) 03.02.01 --

    E-print Network

    Kaplan, Alexander

    ), . , . , , , (Chen, Fang, 1982; Fang, Yu, 2002; Bogner, Arnautov, 2004; Tillich, 2005). , , #12- , (Zhu, Zhang, 1981; Chen, Fang, 1982; Wan, 1984; Wan, Huang, 1987; Tao, 1992; Tang, Liu, 2003; Tillich (Nakai, 1936). , XIX (Ker Gawler, 1822), (Tao, 1992; Fang, Yu, 2002; Tang, Liu, 2003

  20. The Taiwanese-American Occultation Survey: The Multi-Telescope Robotic Observatory

    E-print Network

    M. J. Lehner; C. -Y. Wen; J. -H. Wang; S. L. Marshall; M. E. Schwamb; Z. -W. Zhang; F. B. Bianco; J. Giammarco; R. Porrata; C. Alcock; T. Axelrod; Y. -I. Byun; W. P. Chen; K. H. Cook; R. Dave; S. -K. King; T. Lee; H. -C. Lin; S. -Y. Wang

    2009-03-16

    The Taiwanese-American Occultation Survey (TAOS) operates four fully automatic telescopes to search for occultations of stars by Kuiper Belt Objects. It is a versatile facility that is also useful for the study of initial optical GRB afterglows. This paper provides a detailed description of the TAOS multi-telescope system, control software, and high-speed imaging.

  1. Turning Patrons into Partners When Choosing an Integrated Library System

    ERIC Educational Resources Information Center

    Ryan, Terry

    2004-01-01

    UCLA, which has one of the top 10 research libraries in the country, has been using Taos software since 1996. However in 2001, Sirsi Corp. announced that it was freezing development on Taos software. As the associate university librarian for information technology at UCLA, the author relates that it was his responsibility to lead the way through…

  2. Osteoarthritis at Young Age, a Diagnostic Challenge: A Case of Stickler Syndrome

    PubMed Central

    de Wergifosse, Isabelle; Westhovens, Rene

    2014-01-01

    A young woman presents with severe polyarticular osteoarthritis with relevant family history potentially suggesting a hereditary disease. Previously, the patient’s mother had been diagnosed with rheumatoid arthritis and reported to have suffered from some locomotor problems. Careful clinical evaluation with an extensive personal and familial history pointed towards a diagnosis of Stickler syndrome, an autosomal dominant condition with progressive arthro-ophthalmopathy, (early osteoarthritis and myopia). Following this timely diagnosis, genetic counselling was offered. PMID:25598853

  3. Thermally-assisted-occupation density functional theory with generalized-gradient approximations

    SciTech Connect

    Chai, Jeng-Da, E-mail: jdchai@phys.ntu.edu.tw [Department of Physics, Center for Theoretical Sciences, and Center for Quantum Science and Engineering, National Taiwan University, Taipei 10617, Taiwan (China)] [Department of Physics, Center for Theoretical Sciences, and Center for Quantum Science and Engineering, National Taiwan University, Taipei 10617, Taiwan (China)

    2014-05-14

    We extend the recently proposed thermally-assisted-occupation density functional theory (TAO-DFT) [J.-D. Chai, J. Chem. Phys. 136, 154104 (2012)] to generalized-gradient approximation (GGA) exchange-correlation density functionals. Relative to our previous TAO-LDA (i.e., the local density approximation to TAO-DFT), the resulting TAO-GGAs are significantly superior for a wide range of applications, such as thermochemistry, kinetics, and reaction energies. For noncovalent interactions, TAO-GGAs with empirical dispersion corrections are shown to yield excellent performance. Due to their computational efficiency for systems with strong static correlation effects, TAO-LDA and TAO-GGAs are applied to study the electronic properties (e.g., the singlet-triplet energy gaps, vertical ionization potentials, vertical electron affinities, fundamental gaps, and symmetrized von Neumann entropy) of acenes with different number of linearly fused benzene rings (up to 100), which is very challenging for conventional electronic structure methods. The ground states of acenes are shown to be singlets for all the chain lengths studied here. With the increase of acene length, the singlet-triplet energy gaps, vertical ionization potentials, and fundamental gaps decrease monotonically, while the vertical electron affinities and symmetrized von Neumann entropy (i.e., a measure of polyradical character) increase monotonically.

  4. Thermally-assisted-occupation density functional theory with generalized-gradient approximations

    NASA Astrophysics Data System (ADS)

    Chai, Jeng-Da

    2014-05-01

    We extend the recently proposed thermally-assisted-occupation density functional theory (TAO-DFT) [J.-D. Chai, J. Chem. Phys. 136, 154104 (2012)] to generalized-gradient approximation (GGA) exchange-correlation density functionals. Relative to our previous TAO-LDA (i.e., the local density approximation to TAO-DFT), the resulting TAO-GGAs are significantly superior for a wide range of applications, such as thermochemistry, kinetics, and reaction energies. For noncovalent interactions, TAO-GGAs with empirical dispersion corrections are shown to yield excellent performance. Due to their computational efficiency for systems with strong static correlation effects, TAO-LDA and TAO-GGAs are applied to study the electronic properties (e.g., the singlet-triplet energy gaps, vertical ionization potentials, vertical electron affinities, fundamental gaps, and symmetrized von Neumann entropy) of acenes with different number of linearly fused benzene rings (up to 100), which is very challenging for conventional electronic structure methods. The ground states of acenes are shown to be singlets for all the chain lengths studied here. With the increase of acene length, the singlet-triplet energy gaps, vertical ionization potentials, and fundamental gaps decrease monotonically, while the vertical electron affinities and symmetrized von Neumann entropy (i.e., a measure of polyradical character) increase monotonically.

  5. Treatment modalities of thyroid related orbitopathy

    PubMed Central

    Ahn, Eric S; Subramanian, Prem S

    2014-01-01

    Aims: The aim was to highlight recent advances in the treatment of thyroid eye disease. Settings and Design: Review article. Materials and Methods: Existing literature and the authors’ experience was reviewed. Results: Thyroid ophthalmopathy is a disfiguring and vision-threatening complication of autoimmune thyroid disease that may develop or persist even in the setting of well-controlled systemic thyroid status. Treatment response can be difficult to predict, and optimized algorithms for disease management do not exist. Thyroid ophthalmopathy should be graded for both severity and disease activity before choosing a treatment modality for each patient. The severity of the disease may not correlate directly with the activity; medical treatment is most effective in active disease, and surgery is usually reserved for quiescent disease with persistent proptosis and/or eyelid changes. Conclusions: Intravenous pulsed corticosteroids, orbital radiotherapy, and orbital surgical techniques form the mainstay of current management of thyroid ophthalmopathy. Immunosuppressive and biologic agents may have a role in treating active disease although additional safety and efficacy studies are needed. PMID:25449934

  6. A-site- and/or B-site-modified PbZrTiO3 materials and (Pb, Sr, Ca, Ba, Mg) (Zr, Ti, Nb, Ta)O3 films having utility in ferroelectric random access memories and high performance thin film microactuators

    NASA Technical Reports Server (NTRS)

    Roeder, Jeffrey F. (Inventor); Chen, Ing-Shin (Inventor); Bilodeau, Steven (Inventor); Baum, Thomas H. (Inventor)

    2001-01-01

    A modified PbZrTiO.sub.3 perovskite crystal material thin film, wherein the PbZrTiO.sub.3 perovskite crystal material includes crystal lattice A-sites and B-sites at least one of which is modified by the presence of a substituent selected from the group consisting of (i) A-site substituents consisting of Sr, Ca, Ba and Mg, and (ii) B-site substituents selected from the group consisting of Nb and Ta. The perovskite crystal thin film material may be formed by liquid delivery MOCVD from metalorganic precursors of the metal components of the thin film, to form PZT and PSZT, and other piezoelectric and ferroelectric thin film materials. The thin films of the invention have utility in non-volatile ferroelectric memory devices (NV-FeRAMs), and in microelectromechanical systems (MEMS) as sensor and/or actuator elements, e.g., high speed digital system actuators requiring low input power levels.

  7. Comment on “Magnetostratigraphic study of the Kuche Depression, Tarim Basin, and Cenozoic uplift of the Tian Shan Range, Western China” Baochun Huang, John D.A. Piper, Shoutao Peng, Tao Liu, Zhong Li, Qingchen Wang, Rixiang Zhu [Earth Planet. Sci. Lett., 2006, doi:10.1016/j.epsl.2006.09.020

    NASA Astrophysics Data System (ADS)

    Charreau, Julien; Chen, Yan; Gilder, Stuart; Barier, Laurie

    2008-04-01

    The recent publication of "Magnetostratigraphic study of the Kuche Depression, Tarim Basin, and Cenozoic uplift of the Tian Shan Range,Western China" by B.C. Huang, J.D.A. Piper, S.T. Peng, T. Liu, Z. Li, Q.C. Wang, R.X. Zhu [Earth Planet. Sci. Lett., 2006, doi:10.1016/j.epsl.2006.09.020] discusses the Cenozoic uplift history of the Tianshan Mountains by studying the magnetostratigraphy of Paleogene to Neogene continental sediments from two sections located in the Kuche basin at the northern edge of the Tarim basin. To support their conclusion they reinterpreted a magnetostratigraphic study of the Yaha section, which lies ~ 10 km south of their sections, we previously published [J. Charreau, S. Gilder, Y. Chen, S. Dominguez, J.-P. Avouac, S. Sen, M. Jolivet, Y. Li and W. Wang, Magnetostratigraphy of the Yaha section, Tarim Basin (China): 11 Ma acceleration in erosion and uplift of the Tianshan Mountains, Geology 34(3), 2006, 181­184.]. Here, (1) we argue that the interpretations of the sedimentation rate changes they proposed for the Kuche sections are partially invalid, (2) we disagree with their reinterpretation of the age of the Yaha section, and (3) we think that the way they interpret their AMS data is incorrect.

  8. SimHydro 2010: Hydraulic Modeling and Uncertainty, Sophia-Antipolis, 2-4 June 2010 -DeMarchi, C., Tao, W., Johengen, T.H., Stow, C.A.. -Uncertainty in Phosphorous Load Estimation from a Large Watershed in the Great Lakes Basin

    E-print Network

    Watershed in the Great Lakes Basin UNCERTAINTY IN PHOSPHOROUS LOAD ESTIMATION FROM A LARGE WATERSHED IN THE GREAT LAKES BASIN Incertitude en l'Estimation de la Charge du Phosphore d'un Grand Bassin Versant dans & Ecosystems Research, University of Michigan, Ann Arbor, Michigan 48109-1041, USA johengen@umich.edu , Weichun

  9. The effect of V2O5 on high-frequency properties for W-type barium ferrite composites Z.W. Li, Y. P.Wu and G. Q. Lin Temasek laboratories, National University of Singapore, 10 Kent Ridge Crescent, Singapore, 119260 Tao Liu Singapore Synchrotron Light Source, National University of Singapore, 10 Kent Ridge Crescent, Singapore 117603

    Microsoft Academic Search

    Z. Li; Y. Wu; G. Lin; T. Liu

    2006-01-01

    Ferrite\\/polymer composites were prepared by mixing ferrite powders with epoxy resin. The powders are W-type barium ferrites BaCoxZn2-xFe16O27 (x=1.0, 1.3 and 1.5) doped with V2O5 of 0-1.5 wt%. X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), extended X-ray absorption fine structure spectroscopy (EXAFS), scanning electron microscope (SEM), electric resistivity, static and high-frequency magnetic measurements were performed to study the microstructure, static

  10. TABLE OF CONTENTS VOLUME LXXXVII

    E-print Network

    Glasner, Yair

    NETS HAWK KATZ AND TERENCE TAO --- New bounds for Kakeya problems 231 MARKUS KEEL, HART F. SMITH AND CHRISTOPHER D. SOGGE --- Almost global existence for some semilinear wave equations 265 CARLOS E. KENIG

  11. Effect of strain on geometric and electronic structures of graphene on a Ru(0001) surface This article has been downloaded from IOPscience. Please scroll down to see the full text article.

    E-print Network

    Gao, Hongjun

    of graphene on a Ru(0001) surface Sun Jia-Tao( ), Du Shi-Xuan( ), Xiao Wen-De( ), Hu Hao( ), Zhang Yu-Yang( ), Li Guo( ), and Gao Hong-Jun( ) Nanoscale Physics and Devices Laboratory, Institute of Physics

  12. 75 FR 21963 - Federal Register, Volume 75 Issue 79 (Monday, April 26, 2010)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ...Regulatory Flexibility Analysis Required: Yes Agency Contact: Mark W. Green, Division of Corporation Finance, Securities and...Flexibility Analysis Required: Yes Agency Contact: Josephine J. Tao, Division of Trading and Markets, Securities and Exchange...

  13. Securities and Exchange Commission Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ...Regulatory Flexibility Analysis Required: Yes Agency Contact: Mark W. Green, Division of Corporation Finance, Securities and Exchange...Flexibility Analysis Required: Yes Agency Contact: Josephine J. Tao, Division of Trading and Markets, Securities and Exchange...

  14. Proceedings of the International Workshop on User Profile Data on the

    E-print Network

    Langendoen, Koen

    Tube . . . . . . . . . . . . . . . . . . . . . v M. Rowe TUMS: Twitter-based User Modeling Service. . . . . . . . . . . . . . . . . . . vi K. Tao and Amazon, rely on implicitly or explicitly collected data about their users and their activities to provide

  15. 75 FR 2889 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-International...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-19

    ...Pacific Insulating Material Co., Ltd., Shenzhen, PEOPLE'S REPUBLIC OF CHINA; Lenovo, Quarry Bay, HONG KONG- CHINA; and Quanta Computer Inc., Tao Yuan Shien, TAIWAN, have been added as parties to this venture. Also, Agile Software...

  16. Democritus as Taoist

    E-print Network

    Rivero, A

    2003-01-01

    While similarities do naturally exist between tao and other philosophical systems, for the specific case of Democritus we can argue also the chronological parallels, the parallels in the posterior development (alchemy and mathematics) and the textual parallelism.

  17. Security Lab Series Introduction to Web Technologies

    E-print Network

    Tao, Lixin

    Security Lab Series Introduction to Web Technologies Prof. Lixin Tao Pace University http...........................................................................................................................................1 1.1 Web ArchitectureScript..................................................................................16 4.6 Creating Your First JavaServer Page Web Application

  18. 78 FR 78380 - Notice of Inventory Completion: U.S. Department of the Interior, National Park Service, Fort...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-26

    ...Mexico; Pueblo of Taos, New Mexico; Pueblo of Tesuque, New Mexico; Pueblo of Zia, New Mexico; Pyramid Lake Paiute Tribe of the Pyramid Lake Reservation, Nevada; Shoshone-Paiute Tribes of the Duck Valley Reservation, Nevada;...

  19. 78 FR 72701 - Notice of Inventory Completion: U.S. Department of the Interior, National Park Service, Natural...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-03

    ...Mexico; Pueblo of Taos, New Mexico; Pueblo of Tesuque, New Mexico; Pueblo of Zia, New Mexico; Pyramid Lake Paiute Tribe of the Pyramid Lake Reservation, Nevada; Shoshone-Paiute Tribes of the Duck Valley Reservation, Nevada;...

  20. Compressed sensing for graphs Seeun Umboh

    E-print Network

    Zhu, Xiaojin "Jerry"

    of Artificial Intelligence (www.aaai.org). All rights reserved. 1 (Candes and Tao 2009) gives the better bound of the matrix entries using nuclear norm minimization1 . The Singular Value Thresh- olding(SVT) algorithm

  1. 75 FR 9602 - Ocean Transportation Intermediary License; Applicants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-03

    ...Intermediary Applicants Intertrans Express (NY), Inc., 10 East Merrick Road, 203, Valley Stream, NY 11580. Officer: Chun aka Peter T. Tao, President/ Secretary, (Qualifying Individual). International Trade Brokers and Forwarders Co,...

  2. BLOOD CHARACTERIZATION FROM PULSATILE BIOIMPEDANCE SPECTROSCOPY

    E-print Network

    Adler, Andy

    BLOOD CHARACTERIZATION FROM PULSATILE BIOIMPEDANCE SPECTROSCOPY Tao Dai Systems and Computer of blood using three measuring frequencies. Characterization of blood bioimpedance properties; however, Current bioimpedance spectroscopy measurements of blood are ei- ther in vitro[6

  3. Sea Surface Temperature Anomalies show La Nina, El Nino and Normal Conditions in the Pacific Ocean

    NSDL National Science Digital Library

    Tropical Atmosphere Ocean project

    These TAO project graphics compare sea surface temperature between normal conditions in 1993, El Nino in 1997, and La Nina in 1998. Additional images and background information can also be accessed from this page.

  4. 40 CFR 81.332 - New Mexico.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...Arriba (part) see 40 CFR 81.239 Santa Fe County (part) Remainder of county Taos County...157 Upper Rio Grande Valley Intrastate Santa Fe County (part) Narrow corridor in Santa Fe Unclassifiable/Attainment 1 This...

  5. THE FLAGSHIP RESEARCH JOURNAL OF PRODUCTION AND OPERATIONS MANAGEMENT SOCIETY Volume 22 Number 1 JanuaryFebruary 2013

    E-print Network

    Entekhabi, Dara

    Arash Azadegan, Pankaj C. Patel, Vinit Parida Operational Slack and Venture Survival 19 Ernan Haruvy Responses 178 Baichun Feng, Tao Yao, Bin Jiang Analysis of the Market-Based Adjustable Outsourcing Contract

  6. El Nino-La Nina Cross-section of Temperature and Height Anomalies: January 1997 through March 1999

    NSDL National Science Digital Library

    Greg Shirah

    1999-04-01

    An animation of sea surface temperature anomaly, sea surface height anomaly, and sea temperature anomaly at depth in the Pacific Ocean from January 1997 through March 1999 as measured by NOAA AVHRR, TOPEX Poseidon, and the TAO TRITON Array

  7. El Nino-La Nina Cross-section of Temperature and Height Anomalies: Jan. 1997 through Febr. 1999

    NSDL National Science Digital Library

    Greg Shirah

    1999-04-01

    An animation of sea surface temperature anomaly, sea surface height anomaly, and sea temperature anomaly at depth in the Pacific Ocean from January 1997 through February 1999 as measured by NOAA AVHRR, TOPEX Poseidon, and the TAO TRITON Array

  8. El Nino Zoom to Cross-section of Sea Temperature and Height: January 1997 through March 1998

    NSDL National Science Digital Library

    Greg Shirah

    1998-03-20

    An animation of sea surface temperature, sea surface height, and sea temperature at depth in the Pacific Ocean from January 1997 through March 1998 as measured by NOAA AVHRR, TOPEX Poseidon, and the TAO TRITON Array

  9. El Nino-La Nina Cross-section of Temperature and Height Anomalies: Jan. 1997 through Nov. 1998

    NSDL National Science Digital Library

    Greg Shirah

    1998-11-23

    An animation of sea surface temperature anomaly, sea surface height anomaly, and sea temperature anomaly at depth in the Pacific Ocean from July 1997 through November 1998 as measured by NOAA AVHRR, TOPEX Poseidon, and the TAO TRITON Array

  10. El Nino Zoom to Cross-section of Temperature and Height Anomalies: September 1997 through July 1998

    NSDL National Science Digital Library

    Greg Shirah

    1998-07-01

    An animation of sea surface temperature anomaly, sea surface height anomaly, and sea temperature anomaly at depth in the Pacific Ocean from September 1997 through July 1998 as measured by NOAA AVHRR, TOPEX Poseidon, and the TAO TRITON Array

  11. El Nino-La Nina Zoom to Cross-section of Temperature and Height Anomalies: Jan. 1997 through Nov. 1998

    NSDL National Science Digital Library

    Greg Shirah

    1998-11-23

    An animation of sea surface temperature anomaly, sea surface height anomaly, and sea temperature anomaly at depth in the Pacific Ocean from January 1997 through November 1998 as measured by NOAA AVHRR, TOPEX Poseidon, and the TAO TRITON Array

  12. El Nino Zoom to Cross-section of Temperature and Height Anomalies: July 1997 through August 1998

    NSDL National Science Digital Library

    Greg Shirah

    1998-08-20

    An animation of sea surface temperature anomaly, sea surface height anomaly, and sea temperature anomaly at depth in the Pacific Ocean from July 1997 through August 1998 as measured by NOAA AVHRR, TOPEX Poseidon, and the TAO TRITON Array

  13. El Nino Zoom to Cross-section of Temperature and Height Anomalies: June 1997 through June 1998

    NSDL National Science Digital Library

    Greg Shirah

    1998-06-11

    An animation of sea surface temperature anomaly, sea surface height anomaly, and sea temperature anomaly at depth in the Pacific Ocean from June 1997 through June 1998 as measured by NOAA AVHRR, TOPEX Poseidon, and the TAO TRITON Array

  14. El Nino-La Nina Cross-section of Sea Temperature and Height: July 1997 through November 1998

    NSDL National Science Digital Library

    Greg Shirah

    1998-11-23

    An animation of sea surface temperature, sea surface height, and sea temperature at depth in the Pacific Ocean from July 1997 through November 1998 as measured by NOAA AVHRR, TOPEX Poseidon, and the TAO TRITON Array

  15. El Nino Zoom to Cross-section of Temperature and Height Anomalies: August 1997 through August 1998

    NSDL National Science Digital Library

    Greg Shirah

    1998-08-01

    An animation of sea surface temperature anomaly, sea surface height anomaly, and sea temperature anomaly at depth in the Pacific Ocean from August 1997 through August 1998 as measured by NOAA AVHRR, TOPEX Poseidon, and the TAO TRITON Array

  16. El Nino-La Nina Cross-section of Temperature and Height Anomalies: Jan. 1997 through Dec. 1999

    NSDL National Science Digital Library

    Greg Shirah

    1999-12-21

    An animation of sea surface temperature anomaly, sea surface height anomaly, and sea temperature anomaly at depth in the Pacific Ocean from January 1997 through December 1999 as measured by NOAA AVHRR, TOPEX Poseidon, and the TAO TRITON Array

  17. A Quasi-random Sampling Approach to Image Retrieval Jun Zhou1,2

    E-print Network

    Zhou, Jun

    so as to exploit similarity information in a graph-theoretic setting by using a dynamic clustering of the classifier used in the query operation. In [29], Tao et al. have used an SVM classifier based upon asymmetric

  18. Philosophy Department Fall 2000 Electives

    E-print Network

    Huang, Jianyu

    : Confucianism, Taoism, and Buddhism. Emphasizing social harmony and order, Confucianism deals mainly with human the most natural way to achieve this harmony, Tao. Synthesized as soon as it arrived in China, Buddhism

  19. Philosophy Department Fall 2001 Electives

    E-print Network

    Huang, Jianyu

    : Confucianism, Taoism, and Buddhism. Emphasizing social harmony and order, Confucianism deals mainly with human the most natural way to achieve this harmony, Tao. Synthesized as soon as it arrived in China, Buddhism

  20. Electronic spectroscopy of the ~A1 system of CDCl

    E-print Network

    Reid, Scott A.

    Electronic spectroscopy of the ~A1 A00 $ ~X1 A0 system of CDCl Chong Tao, Calvin Mukarakate, Scott); see Refs. [7,8] for a detailed list of references. For the monohalocarbenes, the two low lying singlet

  1. 40 CFR 81.239 - Upper Rio Grande Valley Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...f)) geographically located within the outermost boundaries of the area so delimited): In the State of New Mexico: Los Alamos County, Santa Fe County, Taos County. Those portions of Rio Arriba County lying east of the Continental...

  2. 40 CFR 81.239 - Upper Rio Grande Valley Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...f)) geographically located within the outermost boundaries of the area so delimited): In the State of New Mexico: Los Alamos County, Santa Fe County, Taos County. Those portions of Rio Arriba County lying east of the Continental...

  3. 40 CFR 81.239 - Upper Rio Grande Valley Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...f)) geographically located within the outermost boundaries of the area so delimited): In the State of New Mexico: Los Alamos County, Santa Fe County, Taos County. Those portions of Rio Arriba County lying east of the Continental...

  4. 40 CFR 81.239 - Upper Rio Grande Valley Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...f)) geographically located within the outermost boundaries of the area so delimited): In the State of New Mexico: Los Alamos County, Santa Fe County, Taos County. Those portions of Rio Arriba County lying east of the Continental...

  5. 40 CFR 81.239 - Upper Rio Grande Valley Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...f)) geographically located within the outermost boundaries of the area so delimited): In the State of New Mexico: Los Alamos County, Santa Fe County, Taos County. Those portions of Rio Arriba County lying east of the Continental...

  6. El Nino Zoom to Cross-section of Temperature and Height Anomalies: July 1997 through October 1998

    NSDL National Science Digital Library

    Greg Shirah

    1998-10-26

    An animation of sea surface temperature anomaly, sea surface height anomaly, and sea temperature anomaly at depth in the Pacific Ocean from July 1997 through October 1998 as measured by NOAA AVHRR, TOPEX Poseidon, and the TAO TRITON Array

  7. Thromboangiitis obliterans with cryoglobulinemia.

    PubMed

    Owlia, Mohammad Bagher; Mehrpoor, Golbarg

    2014-11-01

    Thromboangiitis obliterans (TAO), or Buerger's disease, is a vascular occlusive disease associated with cigarette smoking. It typically affects medium sized vessels of extremities. Basic pathology of TAO is described to be endothelial activation with highly inflammatory intraluminal thrombosis preserving internal elastic membrane. Cryoglobulins are immunoglobulins that precipitate in the cold and dissolve on re-warming. Cryoglobulinemic vasculitis is a typical small vessel disease associated with cryoglobulinemia commonly bearing typical purpuric skin lesions. An association of TAO with cryoglobulinemia is not reported yet. We report a 34-year-old male heavy cigarette smoker seen for extremity pain and cyanosis of left little finger along with skin rashes characteristic of small vessel disease. Initial presentation of his symptoms at winter and unusual purpuric skin lesions led to search for cold-agglutinating globulins in his plasma. He had severe cryoglobulinemia while the other laboratory tests were normal. TAO associated with cryoglobulinemia merges as a possibility. PMID:25404449

  8. Derivation of Newton's Law of Gravitation Based on a Fluid Mechanical Singularity Model of Particles

    E-print Network

    Xiao-Song Wang

    2006-10-25

    We speculate that the universe may be filled with a kind of fluid which may be called aether or tao. Thus, Newton's law of gravitation is derived by methods of hydrodynamics based on a sink flow model of particles.

  9. Buerger’s disease: a 10-year experience in Tehran, Iran

    Microsoft Academic Search

    Hassan Tavakoli; Jalal Rezaii; Khalil Esfandiari; Javad Salimi; Armin Rashidi

    2008-01-01

    The clinical spectrum of Buerger’s disease (TAO; thromboangiitis obliterans) seems to be changing. Considering the lack of\\u000a any formal studies on the epidemiology of this disease in Iran, we evaluated the data of 198 confirmed cases of TAO during\\u000a the period 1996–2006. Diagnosis was based on Papa’s scoring system. All patients were male and aged at the time of diagnosis

  10. Permeability prediction and drainage capillary pressure simulation in sandstone reservoirs

    E-print Network

    Wu, Tao

    2005-02-17

    PERMEABILITY PREDICTION AND DRAINAGE CAPILLARY PRESSURE SIMULATION IN SANDSTONE RESERVOIRS A Dissertation by TAO WU Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements... for the degree of DOCTOR OF PHILOSOPHY December 2004 Major Subject: Geology PERMEABILITY PREDICTION AND DRAINAGE CAPILLARY PRESSURE SIMULATION IN SANDSTONE RESERVOIRS A Dissertation by TAO WU Submitted to Texas A&M University...

  11. High-pressure shock behavior of WC and Ta2O5 powders

    Microsoft Academic Search

    Marcus D. Knudson; William Dodd Reinhart; Tracy John Vogler; Seth Root

    2011-01-01

    Planar shock experiments were conducted on granular tungsten carbide (WC) and tantalum oxide (TaO) using the Z machine and a 2-stage gas gun. Additional shock experiments were also conducted on a nearly fully dense form of TaO. The experiments on WC yield some of the highest pressure results for granular materials obtained to date. Because of the high distention of

  12. Trypanosome Alternative Oxidase Possesses both an N-Terminal and Internal Mitochondrial Targeting Signal

    PubMed Central

    Hamilton, VaNae; Singha, Ujjal K.; Smith, Joseph T.; Weems, Ebony

    2014-01-01

    Recognition of mitochondrial targeting signals (MTS) by receptor translocases of outer and inner membranes of mitochondria is one of the prerequisites for import of nucleus-encoded proteins into this organelle. The MTS for a majority of trypanosomatid mitochondrial proteins have not been well defined. Here we analyzed the targeting signal for trypanosome alternative oxidase (TAO), which functions as the sole terminal oxidase in the infective form of Trypanosoma brucei. Deleting the first 10 of 24 amino acids predicted to be the classical N-terminal MTS of TAO did not affect its import into mitochondria in vitro. Furthermore, ectopically expressed TAO was targeted to mitochondria in both forms of the parasite even after deletion of first 40 amino acid residues. However, deletion of more than 20 amino acid residues from the N terminus reduced the efficiency of import. These data suggest that besides an N-terminal MTS, TAO possesses an internal mitochondrial targeting signal. In addition, both the N-terminal MTS and the mature TAO protein were able to target a cytosolic protein, dihydrofolate reductase (DHFR), to a T. brucei mitochondrion. Further analysis identified a cryptic internal MTS of TAO, located within amino acid residues 115 to 146, which was fully capable of targeting DHFR to mitochondria. The internal signal was more efficient than the N-terminal MTS for import of this heterologous protein. Together, these results show that TAO possesses a cleavable N-terminal MTS as well as an internal MTS and that these signals act together for efficient import of TAO into mitochondria. PMID:24562910

  13. A customized implementation of the FAO land evaluation framework using GIS: the Avenue approach

    E-print Network

    Tao, Ran

    1997-01-01

    A CUSTOMIZED IMPLEMENTATION OF THE FAO LAND EVALUATION FRAMEWORK USING GIS: THE AVENUE APPROACH A Thesis by RAN TAO Submitted to the Office of Graduate Studies of Texas A@M University in partial fulfillment of the requirements for the degree... of MASTER OF SCIENCE May 1997 Major Subject: Geography A CUSTOMIZED IMPLEMENTATION OF THE FAO LAND EVALUATION FRAMEWORK USING GIS: THE AVENUE APPROACH A Thesis by RAN TAO Submitted to Texas ARM University in partial fulfillment of the requirements...

  14. Etiopathogenesis, clinical diagnosis and treatment of thromboangiitis obliterans - current practices.

    PubMed

    Joviliano, Edwaldo Edner; Dellalibera-Joviliano, Renata; Dalio, Marcelo; Evora, Paulo Rb; Piccinato, Carlos E

    2009-01-01

    Thromboangiitis obliterans (TAO) is a segmental inflammatory occlusive disorder that affects small- and medium-sized arteries, and arm and leg veins of young smokers. Several different diagnostic criteria have been offered for the diagnosis of TAO. Clinically, it manifests as migratory thrombophlebitis or signs of arterial insufficiency in the extremities. It is characterized by highly cellular and inflammatory occlusive thrombi, primarily of the distal extremities. Thromboses are often occlusive and sometimes display moderate, nonspecific inflammatory infiltrate, consisting mostly of polymorphonuclear leukocytes, mononuclear cells and rare multinuclear giant cells. The immune system appears to play a critical role in the etiology of TAO. However, knowledge about immunological aspects involved in the progression of vascular tissue inflammation, and consequently, the evolution of this disease, is still limited. There are several studies that suggest the involvement of genetic factors and results have shown increasing levels of antiendothelial cell antibodies in patients with active disease. Vasodilation is impaired in patients with TAO. TAO disorder may actually be an autoimmune disorder, probably initiated by an unknown antigen in the vascular endothelium, possibly a component of nicotine. There are various therapies available for treatment of TAO, but the major and indispensable measure is smoking cessation. Except for discontinuation of tobacco use, no forms of therapy are definitive. Sympathectomy, cilostazol and prostaglandin analogues (prostacyclin or prostaglandin E) have been used in specific conditions. Recently, therapeutic angiogenesis with autologous transplantation of bone marrow mononuclear cells has been studied in patients with critical limb ischemia. PMID:22477511

  15. Thyrotoxic muscle disease

    PubMed Central

    Ramsay, Ian

    1968-01-01

    Evidence suggests that most hyperthyroid patients have a proximal myopathy. The more severe this is the more frequently are distal muscles, and ultimately, bulbar muscles involved. Probably acute thyrotoxic myopathy or encephalopathy supervenes on a previous chronic background or occurs concurrently with skeletal muscle involvement. Using careful electromyographic techniques evidence of myopathy may be found in most thyrotoxics; it disappears with adequate treatment of the primary disease. Myasthenia gravis and periodic paralysis are also associated with thyrotoxicosis and their differentiation is discussed. Infiltrative ophthalmopathy is not related to the effects of excess thyroid hormone, but is possibly due to EPS working in conjunction with LATS. ImagesFig. 2 PMID:4871773

  16. In situ biodegradation of naphthenic acids in oil sands tailings pond water using indigenous algae-bacteria consortium.

    PubMed

    Mahdavi, Hamed; Prasad, Vinay; Liu, Yang; Ulrich, Ania C

    2015-07-01

    In this study, the biodegradation of total acid-extractable organics (TAOs), commonly called naphthenic acids (NAs), was investigated. An indigenous microbial culture containing algae and bacteria was taken from the surface of a tailings pond and incubated over the course of 120days. The influence of light, oxygen and the presence of indigenous algae and bacteria, and a diatom (Navicula pelliculosa) on the TAO removal rate were elucidated. The highest biodegradation rate was observed with bacteria growth only (without light exposure) with a half-life (t(1/2)) of 203days. The algae-bacteria consortium enhanced the detoxification process, however, bacterial biomass played the main role in toxicity reduction. Principal component analysis (PCA) conducted on FT-IR spectra, identified functional groups and bonds (representing potential markers for biotransformation of TAOs) as follows: hydroxyl, carboxyl and amide groups along with CH, arylH, arylOH and NH bonds. PMID:25841188

  17. A modified ELISA accurately measures secretion of high molecular weight hyaluronan (HA) by Graves' disease orbital cells.

    PubMed

    Krieger, Christine C; Gershengorn, Marvin C

    2014-02-01

    Excess production of hyaluronan (hyaluronic acid [HA]) in the retro-orbital space is a major component of Graves' ophthalmopathy, and regulation of HA production by orbital cells is a major research area. In most previous studies, HA was measured by ELISAs that used HA-binding proteins for detection and rooster comb HA as standards. We show that the binding efficiency of HA-binding protein in the ELISA is a function of HA polymer size. Using gel electrophoresis, we show that HA secreted from orbital cells is primarily comprised of polymers more than 500 000. We modified a commercially available ELISA by using 1 million molecular weight HA as standard to accurately measure HA of this size. We demonstrated that IL-1?-stimulated HA secretion is at least 2-fold greater than previously reported, and activation of the TSH receptor by an activating antibody M22 from a patient with Graves' disease led to more than 3-fold increase in HA production in both fibroblasts/preadipocytes and adipocytes. These effects were not consistently detected with the commercial ELISA using rooster comb HA as standard and suggest that fibroblasts/preadipocytes may play a more prominent role in HA remodeling in Graves' ophthalmopathy than previously appreciated. PMID:24302624

  18. Isolation of a Gene Responsible for the Oxidation of trans-Anethole to para-Anisaldehyde by Pseudomonas putida JYR-1 and Its Expression in Escherichia coli

    PubMed Central

    Han, Dongfei; Ryu, Ji-Young; Kanaly, Robert A.

    2012-01-01

    A plasmid, pTA163, in Escherichia coli contained an approximately 34-kb gene fragment from Pseudomonas putida JYR-1 that included the genes responsible for the metabolism of trans-anethole to protocatechuic acid. Three Tn5-disrupted open reading frame 10 (ORF 10) mutants of plasmid pTA163 lost their abilities to catalyze trans-anethole. Heterologously expressed ORF 10 (1,047 nucleotides [nt]) under a T7 promoter in E. coli catalyzed oxidative cleavage of a propenyl group of trans-anethole to an aldehyde group, resulting in the production of para-anisaldehyde, and this gene was designated tao (trans-anethole oxygenase). The deduced amino acid sequence of TAO had the highest identity (34%) to a hypothetical protein of Agrobacterium vitis S4 and likely contained a flavin-binding site. Preferred incorporation of an oxygen molecule from water into p-anisaldehyde using 18O-labeling experiments indicated stereo preference of TAO for hydrolysis of the epoxide group. Interestingly, unlike the narrow substrate range of isoeugenol monooxygenase from Pseudomonas putida IE27 and Pseudomonas nitroreducens Jin1, TAO from P. putida JYR-1 catalyzed isoeugenol, O-methyl isoeugenol, and isosafrole, all of which contain the 2-propenyl functional group on the aromatic ring structure. Addition of NAD(P)H to the ultrafiltered cell extracts of E. coli (pTA163) increased the activity of TAO. Due to the relaxed substrate range of TAO, it may be utilized for the production of various fragrance compounds from plant phenylpropanoids in the future. PMID:22610435

  19. Computing the Minimum Recombinant Haplotype Configuration from Incomplete Genotype Data on a Pedigree by Integer Linear

    E-print Network

    Li, Jing

    on a Pedigree by Integer Linear Programming Jing Li Tao Jiang Abstract We study the problem of reconstructing of recombinants when a significant fraction of alleles are missing. This paper presents an effective integer, pedigree analysis, recombination, missing data imputation, integer linear programming, branch

  20. DOI: 10.1002/adfm.200701120 Nanostructured Sheets of TiO Nanobelts for Gas Sensing and

    E-print Network

    Wang, Zhong L.

    scaled-up. The FULLPAPER [Ã?] Prof. H. Liu, Prof. J. Wang, Prof. X. Tao, Prof. J. Jiao, Prof. D. Liu, Y and Antibacterial Applications** By Yanmin Wang, Guojun Du, Hong Liu,* Duo Liu, Shubin Qin, Na Wang, Chenguo Hu-temperature treatment. Tita- nium oxide can also form many different 3D crystalline polymorphs and 2D layered structures

  1. On the Minimum Common Integer Partition Problem Nanyang Technological University

    E-print Network

    Chen, Xin

    . L. Liu and Z. Liu got their Ph.D. degrees under the guidance of Professor T. Jiang from LIU Google Inc. ZHENG LIU City of Hope, National Medical Center AND TAO JIANG University of California the Department of Computer Science and Engineering, University of California at Riverside, USA. Currently L. Liu

  2. Low-altitude atmospheric wind measurement from the combined Mie and Rayleigh

    E-print Network

    linewidth, 100 MHz, and Z.-S. Liu, D. Wu, J.-T. Liu, K.-L. Zhang, W.-B. Chen, and X.-Q. Song by Doppler lidar with an iodine filter Zhi-Shen Liu, Dong Wu, Jin-Tao Liu, Kai-Lin Zhang, Wei-Biao Chen, Xiao

  3. Measuring Bulk Properties of Sound-Absorbing Materials using the Two-Source Method

    E-print Network

    Seybert, Andrew F.

    noise. Normally, the sound absorption coefficient and surface impedance are used to characterize sound suitable in computational models of absorptive components like seats or thick sections of sound03NVC-200 Measuring Bulk Properties of Sound-Absorbing Materials using the Two-Source Method Z. Tao

  4. Experimental Investigation of Natural Convection in Trombe Wall Systems

    E-print Network

    Chen, B.; Zhao, J.; Chen, C.; Zhuang, Z.

    2006-01-01

    -storey building [J]. Energy and Buildings, 2002, 34(1): 93?104. [10] Adrian Bejan? Heat Transfer[M]? New York: John Wiley & Sons Incorporation, 1993. [11] Shiming Yang, Tao Wenquan. Heat transfer (third edition) [M]. Beijing: higher education publisher...

  5. Shape modeling and matching in identifying 3D protein structures

    E-print Network

    Ju, Tao

    correspondence problem in a noise-abundant envi- ronment to be solved effectively using graph matching. 1Shape modeling and matching in identifying 3D protein structures Sasakthi Abeysinghe a, Tao Ju protein structures from scalar volumes. The input to our method is a sequence of -helices that make up

  6. SmartLoc: Push the Limit of the Inertial Sensor Based Metropolitan Localization Using Smartphone

    E-print Network

    Li, Xiang-Yang

    Cheng Bo Illinois Institute of Technology Chicago, IL 60616, USA cbo@hawk.iit.edu Xiang-Yang Li Illinois Chicago, IL 60616, USA tjung@hawk.iit.edu Xufei Mao Tsinghua University Beijing, China xufei.mao@gmail.com Yue Tao Illinois Institute of Technology Chicago, IL 60616, USA ytao6@hawk.iit.edu ABSTRACT We present

  7. Single-cell-gap transflective liquid-crystal display and the use of photoalignment Lishuang Yao

    E-print Network

    Single-cell-gap transflective liquid-crystal display and the use of photoalignment technology Tao Du Lishuang Yao Vladimir G. Chigrinov Hoi-sing Kwok Abstract -- In this paper, transflective liquid-crystal-display liquid-crystal modes are applied to the transmissive and reflective subpixels of the transflective LCD

  8. A Review of Current Techniques for Measuring Muffler Transmission Loss

    E-print Network

    Seybert, Andrew F.

    03NVC-38 A Review of Current Techniques for Measuring Muffler Transmission Loss Z. Tao and A. F common approach for measuring the transmission loss of a muffler is to determine the incident power- source method. Both methods are demonstrated on two muffler types: (1) a simple expansion chamber and (2

  9. RESEARCH ARTICLE Open Access Community terminal restriction fragment length

    E-print Network

    Palmer, Michael W.

    insights into the diversity and dynamics of leaf endophytic bacteria Tao Ding1 , Michael W Palmer2 and Ulrich Melcher1* Abstract Background: Plant endophytic bacteria play an important role benefiting plant.05) to the distribution of leaf endophytic bacteria, with host species being the most important, followed by sampling

  10. LOGO: A Long-Short User Interest Integration in Personalized News Recommendation

    E-print Network

    Li, Tao

    , Tao Li School of Computing and Information Sciences Florida International University Miami, FL 33199's reading history as a whole, and summarize the history to be the user's profile [2, 8]. [7] postulated of this work for personal or classroom use is granted without fee provided that copies are not made

  11. News Recommendation via Hypergraph Learning: Encapsulation of User Behavior and News Content

    E-print Network

    Li, Tao

    School of Computing and Information Sciences Florida International University Miami, FL 33199 lli003@cs.fiu.edu Tao Li School of Computing and Information Sciences Florida International University Miami, FL 33199 hypergraph to model various high-order re- lations among different objects in news data, and formulate news

  12. C4 expansion in the central Inner Mongolia during the latest Miocene and early Pliocene

    E-print Network

    Wang, Yang

    C4 expansion in the central Inner Mongolia during the latest Miocene and early Pliocene Chunfu Zhang a, , Yang Wang a , Tao Deng b , Xiaoming Wang c , Dana Biasatti a , Yingfeng Xu a , Qiang Li b of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing, 100044, PR China c

  13. CONGESTION MANAGEMENT ALLOCATION IN MULTIPLE TRANSACTION NETWORKS

    E-print Network

    Gross, George

    requirement is that the congestion management and pricing be nondiscriminatory and transparent. Various] for the so-called Poolco paradigm. In the nodal pricing approach, congestion management is performed throughCONGESTION MANAGEMENT ALLOCATION IN MULTIPLE TRANSACTION NETWORKS Shu Tao George Gross ABB Energy

  14. Short-Term Solar Energy Forecasting Using Wireless Sensor Networks

    E-print Network

    Cerpa, Alberto E.

    Short-Term Solar Energy Forecasting Using Wireless Sensor Networks Stefan Achleitner, Tao Liu an advantage for output power prediction. Solar Energy Prediction System Our prediction model is based variability of more then 100 kW per minute. For practical usage of solar energy, predicting times of high

  15. Stand-up magnetic metamaterials at terahertz frequencies

    E-print Network

    Zhang, Xin

    Stand-up magnetic metamaterials at terahertz frequencies Kebin Fan,1 Andrew C. Strikwerda,2 Hu Tao, the characterization of these metamaterials shows a strong response induced purely by the magnetic field. The retrieved for both single and broad side coupled split rings. Our 3D metamaterial examples pave the way towards

  16. Flexible Terahertz Metamaterials: Towards a Terahertz Metamaterial Invisible Cloak , N. I. Landy2

    E-print Network

    Flexible Terahertz Metamaterials: Towards a Terahertz Metamaterial Invisible Cloak Hu Tao1 , N. I In this work, we present flexible metamaterials on free standing polyimide substrates operating at terahertz (THz) frequencies range. The successful demonstration of THz flexible metamaterials provides a path

  17. Microwave and Terahertz wave sensing with metamaterials

    E-print Network

    Zhang, Xin

    Microwave and Terahertz wave sensing with metamaterials Hu Tao,1 Emil A. Kadlec,2 Andrew C designed, fabricated, and characterized metamaterial enhanced bimaterial cantilever pixels for far codes: (160.3918) Metamaterials; (040.2235) Detectors, Far infrared or terahertz; (050.6875) Three

  18. Mouse Repository Strain Details

    Cancer.gov

    Qingcong Lin, Alan B. Clark, Scott D. McCulloch, Tao Yuan, Roderick T. Bronson, Thomas A. Kunkel, and Raju Kucherlapati. Increased Susceptibility to UV-Induced Skin Carcinogenesis in Polymerase eta-deficient Mice. Cancer Res. 66, 87-94, 2006.

  19. Performance Evaluation of Ultra-tight Integration of GPS/Vehicle Sensors for Land

    E-print Network

    Calgary, University of

    areas including software receiver development, satellite-based navigation, inertial navigation are used to constrain the inertial navigation error. The violations of non-holonomic constraints Navigation Tao Li, Mark G. Petovello and G. Lachapelle Position, Location And Navigation (PLAN) Group

  20. Targets for early discoveries at the LHC

    E-print Network

    Targets for early discoveries at the LHC Lian-Tao Wang University of Chicago 04/11/2011 Monday to emphasize less "well-known" or less "well-mentioned" but not "strange" channels. In the next year or so, LHC

  1. 130 IEEE TRANSACTIONS ON NEURAL NETWORKS, VOL. 19, NO. 1, JANUARY 2008 Multiclass Posterior Probability

    E-print Network

    Alpaydýn, Ethem

    130 IEEE TRANSACTIONS ON NEURAL NETWORKS, VOL. 19, NO. 1, JANUARY 2008 Multiclass Posterior Abstract--Tao et al. have recently proposed the posterior proba- bility support vector machine (PPSVM) which uses soft labels de- rived from estimated posterior probabilities to be more robust to noise

  2. Structural Evolving Sequence and Porous Ba6Zr2Nb8O30 Ferroelectric Ceramics with Ultrahigh Breakdown Field and Zero Strain

    E-print Network

    Cao, Wenwu

    dielectric constant, highest electric field breakdown strength, and nearly zero macroscopic electric field Breakdown Field and Zero Strain Shan-Tao Zhang,, Guoliang Yuan,§, Jun Chen,¶ Zheng-Bin Gu, Bin Yang,k Jiang counterparts and can be well understood by using brick-wall model. Our results may provide useful information

  3. IOP PUBLISHING JOURNAL OF PHYSICS D: APPLIED PHYSICS J. Phys. D: Appl. Phys. 41 (2008) 232004 (5pp) doi:10.1088/0022-3727/41/23/232004

    E-print Network

    Huang, Jianyu

    -standing highly-flexible polyimide substrates Hu Tao1 , A C Strikwerda2 , K Fan1 , C M Bingham3 , W J Padilla3 technological impetus to create sources, detectors and components at terahertz frequencies to realize the unique potential of THz radiation [10­13]. Metamaterials are expectedtoplayanimportantroleinthisregardasevidencedby

  4. Noise reduction in lidar signal based on discrete wavelet transform

    E-print Network

    Hefei Institute of Intelligent Machines

    range is often limited by signal- to-noise ratio (SNR). The reason is that noises or interferencesNoise reduction in lidar signal based on discrete wavelet transform Hai-Tao Fang a,b,*, De 2004 Abstract Lidar is an efficient tool for remotely monitoring targets or objects, but the effective

  5. Continuous Remote Mobile Identity Management Using Biometric Integrated Touch-Display

    E-print Network

    Carbunar, Bogdan

    Continuous Remote Mobile Identity Management Using Biometric Integrated Touch-Display Tao Feng of mobile devices and applications introduces new security and privacy vulnerabilities for the remote login steps and (ii) continuous identity management based on fingerprint biometric, where each user

  6. Extraordinary expansion of a Sorangium cellulosum genome from an alkaline

    E-print Network

    Cai, Long

    -feng Li1 , Ran Peng1 , Li-ping Zhu1 , Tao Zhou2 , Lu-guang Wang1 , Shu-guang Li1 , Xiao-bo Zhang2 , Wei Hu1 , Zhi-hong Wu1 , Nan Qin2 & Yue-zhong Li1 1 State Key Laboratory of Microbial Technology, School

  7. SURNAME GIVEN NAME AFFILIATION BIANE Philippe

    E-print Network

    Yao, Jian-Feng

    of Scieneces #12;Feuille1 Page 2 YAO YAO ZHANG ZHANG ZHENG Jianfeng University of Hong Kong and Université de Fourier SHI SILVERSTEIN Jack SU TAO TRUQUET Université de Rennes 1 WANG Li-Li WANG WANG WANG WANG XIAO XIE University Jin-Qing Chinese Academy of Scieneces Jun-Shan Zhejiang University Yong-Xiao Chinese Academy

  8. CNR GRADUATION SURVEY RESULTS Fall, 1999

    E-print Network

    ,000) · Colorado Natural Heritage Program · National Park Service (Yellowstone NP) · The Rio Grande Restaurant for work 1 is taking time off 3 have found employment (Avg. Salary: $20,000) · Ag Wassenar · National Park Service · Ski Taos 60% are employed or attending grad school #12;NRM (15 graduates): 5

  9. Intravenous and oral alfentanil as in vivo probes for hepatic and first-pass

    E-print Network

    Steinbach, Joe Henry

    ) (hepatic and intestinal CYP3A inhibition), grapefruit juice (selective intestine CYP3A inhibition.8 and 10.9 3.5 mL · kg 1 · min 1 , respectively, for MDZ and ALF. After rifampin, TAO, and grapefruit juice

  10. What is the mean seasonal cycle of surface heat flux in the equatorial Pacific?

    NASA Astrophysics Data System (ADS)

    Wang, Weimin; McPhaden, Michael J.

    2001-01-01

    The mean seasonal cycles of six state-of-the-art surface heat flux products (three based on widely available data and three based on numerical model reanalysis fields) are compared in the equatorial Pacific with heat fluxes computed from Tropical Atmosphere-Ocean (TAO) buoy data. Net surface heat flux and individual flux components derived from these products exhibit large deviations from TAO. We find that a significant contribution to these differences, which are often 50 W m-2 or more for net flux, is the use of systematically biased bulk variables in the computation of turbulent surface heat fluxes. We also find that for some products, compensating errors in bulk variables lead to fortuitous agreement with turbulent heat fluxes estimated from TAO. Finally, comparisons of TAO-derived fluxes with tuned and untuned heat flux estimates from the Comprehensive Ocean Atmosphere Data Set indicate better agreement with untuned fluxes, suggesting that commonly used ad hoc strategies to close the global ocean heat budget are not strictly valid.

  11. Self-Rectifying Effect in Resistive Switching Memory Using Amorphous InGaZnO

    NASA Astrophysics Data System (ADS)

    Lee, Jin-Woo; Kwon, Hyeon-Min; Kim, Myeong-Ho; Lee, Seung-Ryul; Kim, Young-Bae; Choi, Duck-Kyun

    2014-05-01

    Resistance random access memory (ReRAM) has received attention as next-generation memory because of its excellent operating properties and high density integration capability as a crossbar array. However, the application of the existing ReRAM as a crossbar array may lead to crosstalk between adjacent cells due to its symmetric I- V characteristics. In this study, the self-rectifying effect of contact between amorphous In-Ga-Zn-O (a-IGZO) and TaO x was examined in a Pt/a-IGZO/TaO x /Al2O3/W structure. The experimental results show not only self-rectifying behavior but also forming-free characteristics. During the deposition of a-IGZO on the TaO x , an oxygen-rich TaO x interfacial layer was formed. The rectifying effect was observed regardless of the interface formation and is believed to be associated with Schottky contact formation between a-IGZO and TaO x . The current level remained unchanged despite repeated DC sweep cycles. The low resistance state/high resistance state ratio was about 101 at a read voltage of -0.5 V, and the rectifying ratio was about 103 at ±2 V.

  12. Automatic Lens Design for Space Applications Project No: 8788005ISRODKSH

    E-print Network

    Bhashyam, Srikrishna

    1 Automatic Lens Design for Space Applications Project No: 8788005ISRODKSH INVESTIGATORS (a) From l OUT: I. THERMAL ANALYSIS PROGRAM A program TAOS ( Thermal Analysis or Optical Systems), Version 1 of an actually manufactured lens does not, generally, match the ideal performance of the lens due to deviations

  13. Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. Modeling of Lattice Parameter in the Ni-Al System

    E-print Network

    Chen, Long-Qing

    Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. Modeling of Lattice Parameter in the Ni-Al System Tao Wang; Jingzhi Zhu; Rebecca A MacKay; Long #12;Reproduced with permission of the copyright owner. Further reproduction prohibited without

  14. An Asian Perspective on Organ Transplantation

    Microsoft Academic Search

    Michael Cheng-Tek Tai

    2009-01-01

    Confucianism, Taoism, Buddhism, Hinduism and Shintoism have largely shaped the ways of Asian living. Since these cultural and religious schools were established long ago before the dawn of modern medical technology, and all of them stress the importance of abiding in the natural order of Tao\\/Dharma, how would they view organ transplantation? This article discusses the teachings of Confucianism, Taoism

  15. Transactions of the ASAE Vol. 48(4): 1471-1479 E 2005 American Society of Agricultural Engineers ISSN 0001-2351 1471

    E-print Network

    He, Brian

    acid (VLCMFA). EA has 22 carbon atoms in its straight-chain molecule and one double bond between C13 by the Food & Process Engineering Institute Division of ASAE in July 2005. The authors are Chunchang Tao of Biological and Agricultural Engineering, University of Idaho, Moscow, Idaho. Corresponding author: B. Brian

  16. Semi-supervised Learning for Music Artists Style Identification

    E-print Network

    Li, Tao

    de- liberately explore different lyrical and musical styles. Those types of music are beyondSemi-supervised Learning for Music Artists Style Identification Tao Li School of Computer Science, lyrics, content 1. INTRODUCTION This paper addresses the issue of identifying the artist style. Our focus

  17. What%was%Transitioned? When? To%What%Organization(s)/group(s)? Benefit%of%transition Miniature)Autonomous)Plume)Recorder ongoing)

    E-print Network

    )Technology 2014 NMFS)Regional)Science)Centers;)NOS)Marine) Sanctuaries,)National)Park)Service Acoustic)noise)worldwide)to)identify)and)discover)hydrothermal)plumes) that)enhance)our)knowledge)of)seafloor)tectonic)systems. TAO)Array 2007C2012 NWS/National International)Argo)community Improves)delayedCmode)quality)control)of)Argo)data PIRATA)Array 2008C2010 IMPE

  18. Using Complete Machine Simulation for Software Power Estimation: The SoftWatt Approach

    E-print Network

    John, Lizy Kurian

    Gurumurthi Anand Sivasubramaniam Mary Jane Irwin N. Vijaykrishnan Mahmut Kandemir Dept. of Computer Science,anand,mji,vijay,kandemirg@cse.psu.edu Tao Li Lizy Kurian John Dept. of Electrical and Computer Engineering University of Texas at Austin, Austin, TX 78712 ftli3,ljohng@ece.utexas.edu Abstract Power dissipation has become one of the most

  19. Graduate Seminars Microbiology 601 -SPEAKERS WINTER 2014 Time and Location: Wednesdays 12:00 1:00 pm in BI211

    E-print Network

    Habib, Ayman

    Graduate Seminars ­ Microbiology 601 - SPEAKERS ­ WINTER 2014 Time and Location: Wednesdays 12:00 ­ 1:00 pm in BI211 Date Presenter Lab Topic January 8 Lindsay Rollick Voordouw Microbiology Voordouw Microbially influenced corrosion (MIC) February 5 GUEST SPEAKER: Dr. Tao Dong Vibrio cholera type

  20. Post-doctoral Research Associate Department of Biology, University of Florida

    E-print Network

    Lichstein, Jeremy W.

    1 Tao Zhang Post-doctoral Research Associate Department of Biology, University of Florida and process-based modeling 1995-1998 M.S., Remote Sensing, Institute of Remote Sensing and GIS, Peking Professional Experience 2011-present Post-doctoral Research Associate Department of Biology, University

  1. Post-doctoral Research Associate, Department of Biology 220 Bartram Hall, PO Box 118525, University of Florida, Gainesville, FL 32611

    E-print Network

    Lichstein, Jeremy W.

    1 Tao Zhang Post-doctoral Research Associate, Department of Biology 220 Bartram Hall, PO Box 118525 of Remote Sensing and GIS, Peking University, Beijing, China Thesis: Modeling microwave backscattering Department of Biology, University of Florida, Gainesville, Florida 2009-2011 Post-doctoral Research Associate

  2. ehirpxf: A Cost-Effective Way to Implement Full Map Directory-Based

    E-print Network

    John, Lizy Kurian

    ehirpxf: A Cost-Effective Way to Implement Full Map Directory-Based Cache Coherence Protocols Tao full map directory tracks the exact caching status for each shared memory block and is designed to be efficient and simple. Unfortunately, the inherent directory size explosion makes it unsuitable for large

  3. ECAPT'94: PORTO 2426 March 1994, Third Meeting of BRITEEURAM Concerted Action on Process VisionGuided Flame Control Using Fuzzy Logic

    E-print Network

    automatically. Fig. 1 shows the basic structure of the fuzzy flame controller. The laboratory test plant Tomography ae Vision­Guided Flame Control Using Fuzzy Logic and Neural Networks \\Lambda Wenjing Tao and Hans This paper describes a vision­guided closed loop control for stationary luminous flames using fuzzy logic

  4. Temporal Image Reconstruction in Electrical Impedance Tomography

    E-print Network

    Adler, Andy

    ) calculates images of the body from body impedance measurements. While the spatial resolution of these images of the others. In this paper, we are interested in approaches to image a body which is undergoing fast changesTemporal Image Reconstruction in Electrical Impedance Tomography Andy Adler1 , Tao Dai1 , William R

  5. Opportunistic Source Coding for Data Gathering in Wireless Sensor Networks

    E-print Network

    1 Opportunistic Source Coding for Data Gathering in Wireless Sensor Networks Tao Cui, Lijun Chen capacity of multihop wireless networks, an important topic addressed by wireless sensor networks community for correlated data gathering in wireless sensor networks, which ex- ploits the broadcast nature of wireless

  6. Obstacles to the application of soil and water conservation practices on tenant-operated farms cooperating with the Navarro-Hill Soil Conservation District

    E-print Network

    Boykin, Calvin C

    1956-01-01

    veiny vs. lationa 'n . ". 'Sni leant cha:actsriatica bo' assn farms, 'lao, if not c*atad, '. he implication often remains that acoompU. shmsntc bg oMnar-op. ". ratora is the "ideal" or standard fox corn parin8 ot. lex' ~? ~ . , hera ths buddeting tao...

  7. DOI: 10.1002/zaac.200700505 Syntheses, Structures and Magnetic Properties of Two Mixed-Valent Disc-like

    E-print Network

    Gao, Song

    CH2O)3 3 , nmdea CH3N(CH2CH2O)2 2 ) Tao Liu, Bing-Wu Wang, Yi-Hong Chen, Zhe-Ming Wang*, and Song Gao nuclearity up to 84 [3] * Prof. Zhe-Ming Wang, Prof. Song Gao Beijing National Laboratory for Molecular

  8. Hierarchical self-assembly of DNA into symmetric supramolecular polyhedra

    E-print Network

    Jiang, Wen

    LETTERS Hierarchical self-assembly of DNA into symmetric supramolecular polyhedra Yu He1 , Tao Ye1 approach to forming DNA polyhedra is a one-pot self- assembly process illustrated in Fig. 1: individual then further assemble into polyhedra through sticky-end asso- ciation between the tiles. The three

  9. Islam, Gender, and Formal Shari'a in Indonesia

    Microsoft Academic Search

    Lily Zakiyah Munir

    The above remark is cited by Annemarie Schimmel in her foreword to The Tao of Islam (Murata 1992, vii). Winternitz' observation is particularly evident when put in the context of Islam, as Schimmel contends that 'it is certainly easier to look only at the surface … of polygamy and easy divorce and … purdah … than to try to see

  10. SUBMIT TO IEEE TIP 1 Motion-Aware Gradient Domain

    E-print Network

    O'Brien, James F.

    2013AA013903) and the Israel Science Foundation (grant no. 324/11). T. Chen, J.-Y. Zhu and S.-M. HuSUBMIT TO IEEE TIP 1 Motion-Aware Gradient Domain Video Composition Tao Chen, Jun-Yan Zhu, Ariel Shamir, and Shi-Min Hu Abstract--For images, gradient domain composition methods like Poisson blending

  11. SumView: A Web-based engine for summarizing product reviews and customer opinions

    E-print Network

    Li, Tao

    a , Shenghuo Zhu b , Tao Li a, a School of Computing and Information Sciences, Florida International University decisions on whether to purchase the products (Hu & Liu, 2004). On one hand, mer- chants selling products focuses on opinion feature extraction and adjective orientation identification. For example, Hu and Liu Hu

  12. The Asia Oceania Human Proteome Organisation Membrane Proteomics Initiative. Preparation and characterization of the carbonate-washed

    E-print Network

    Chait, Brian T.

    , China; 16 School of Traditional Chinese Medicine, Chang Gung University, Tao-Yuan, Taiwan; 17 Medical Proteomics Laboratory, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Center, Beijing Institute of Radiation Medicine, Beijing, P. R. China 6 Department of Biochemistry

  13. ION GNSS 2009, Session A5, Savannah, GA, 22-25 September 2009 1/15 Robust Beamforming for GNSS Synthetic

    E-print Network

    Calgary, University of

    software receiver design, digital signal processing, satellite-based navigation, inertial navigation Synthetic Antenna Arrays Tao Lin, Ali Broumandan, John Nielsen, Cillian O'Driscoll and Gerard Lachapelle are in the area of software receiver for GNSS, particularly in relation to weak signal acquisition and ultra

  14. Surface Energy Induced Patterning of Polymer Nanostructures for Cancer Diagnosis and Therapy

    E-print Network

    Hu, Wenchuang "Walter"

    , dimensions, and uniformity, but without changing/damaging their active bio-functionality. Available Wenchuang (Walter) Hu, Member, IEEE, Fern Yoon, Adam Crouch, Student Member, IEEE, Li Tao, Student Member be stimulated: for example, functionalized nanoparticles or nanoscale capsules for advanced delivery, targeting

  15. A Global Approach for Reduced-Order Models of Flapping Flexible Wings

    E-print Network

    Wei, Mingjun

    provided by engines and the lift provided by fixed wings, which led to a great success of modern airplanes classical Reynolds number. At low Reynolds number regime, conventional fixed-wing airplane suffers with lowA Global Approach for Reduced-Order Models of Flapping Flexible Wings Mingjun Wei , Tao Yang New

  16. Numerical Study of Flexible Flapping Wing Propulsion , Mingjun Wei

    E-print Network

    Wei, Mingjun

    regime, conventional fixed-wing airplane suffers with low flight efficiency and small stall angleNumerical Study of Flexible Flapping Wing Propulsion Tao Yang , Mingjun Wei New Mexico State In this study, we apply a strong-coupling approach to simulate highly flexible flapping wings interacting

  17. Numerical Study of Flexible Flapping Wing Propulsion and Mingjun Wei

    E-print Network

    Wei, Mingjun

    of immersed boundary method, while the rest of the wing moves passively through elasticity and fluid­structure interest in the flapping wing design. At low Reynolds number, conventional fixed- wing airplanes sufferNumerical Study of Flexible Flapping Wing Propulsion Tao Yang and Mingjun Wei New Mexico State

  18. Trial prospector: An automated clinical trials eligibility matching program. | accrualnet.cancer.gov

    Cancer.gov

    Parchman AJ,Zhang G-Q,Mergler P,Barnholtz-Sloan J,Lanese R,Miller DM,Opper C,Sahoo S,Tao S,Teagno J,Warfe J,Meropol NJ. University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH. ASCO 2013 Annual Meeting. 2013 May 31. 2013 Jun 04.

  19. Au DDT 127 Au DDT

    E-print Network

    Hwang, Sung Woo

    Au . [1] Yu Chen, Xihua Wang, Shyamsunder Erramilli, and Pritiraj Mohanty, "Silicon, David A. Corley, Meng Lu, Neil Halen Di Spigna, Jianli He, David P. Nackashi, Paul D. Franzon, and James, 2010 Au DDT 129 2009 [5] Erica S. Forzani, Xiulan Li, Peiming Zhang, Nongjian Tao, Ruth Zhang

  20. Journal of Climate EARLY ONLINE RELEASE

    E-print Network

    Nigam, Sumant

    . Sun, C. Wang, S. Xie, J. Yu, T. Zhang, and M. Zhao, 2013: North American Climate in CMIP5 Experiments-Ping Xie, Jin-Yi Yu, Tao Zhang, Ming Zhao8 Justin Sheffield, Department of Civil and Environmental5 Langenbrunner, Eric Maloney, Annarita Mariotti, Joyce E. Meyerson, J. David Neelin,6 Sumant Nigam

  1. pour obtenir le grade de DOCTEUR DE L'ECOLE CENTRALE DE LYON

    E-print Network

    Paris-Sud XI, Université de

    . Przemyslaw Szeptycki, Boyang Gao, Ningning Liu, Yu Zhang and Tao Xu. My spe- cial thanks are due to Dr. Di Safran Examinateur Prof. Xianfeng DAVID GU State University New York at Stony Brook Examinateur Prof-advisor. Moreover, I would also like to express my deeply-felt thanks to Prof. Xianfeng David Gu, for teaching me

  2. North American Climate in CMIP5 Experiments.1 Part II: Evaluation of 20th Century Intra-Seasonal to Decadal Variability2

    E-print Network

    Ruiz-Barradas, Alfredo

    Seager, Yolande L. Serra, De-Zheng Sun, Chunzai6 Wang, Shang-Ping Xie, Jin-Yi Yu, Tao Zhang, Ming Zhao7 Mariotti, Joyce E. Meyerson, Sumant Nigam, J. David Neelin, Zaitao5 Pan, Alfredo Ruiz-Barradas, Richard Baird Langenbrunner, Joyce E. Meyerson, J. David Neelin, Department of Atmospheric and Oceanic9 Sciences

  3. Essays on Extended Service Contracts May 1st, 2008

    E-print Network

    Sadeh, Norman M.

    1 Essays on Extended Service Contracts Tao Chen Defense May 1st, 2008 #12;2 Abstract Extended. Essay 1: "Why Do Consumers Buy Extended Service Contracts?" The first essay in my dissertation examines of loss, the extent of loss, risk aversion, and the amount of the insurance premium. This essay examines

  4. A TAXONOMIC RE-EVALUATION OF Goniurosaurus hainanensis (SQUAMATA: EUBLEPHARIDAE) FROM HAINAN ISLAND, CHINA

    E-print Network

    Murphy, Bob

    , CHINA Christopher Blair,1,2 Nikolai L. Orlov,3,4 Hai-tao Shi,4,5 and Robert W. Murphy1,2,4 Submitted, Vietnam, and Japan (Orlov and Darevsky, 1999; Grismer et al., 2002). Little is known regarding the ecology within primary rain- forest, usually adjacent to nearby streams (Orlov and Darevsky, 1999). Grismer et al

  5. Efficacy of Physical Therapy Treatment on Patients with Temporomandibular Disorder at 6, 12, 18, and 24 Months Post-discharge

    Microsoft Academic Search

    Erin Calhoun; Makindra Winters

    2005-01-01

    Background and purpose. This study was intended to assess the efficacy of physical therapy treatment on patients with various temporomandibular disorders at 6, 12, 18, and 24 months after their discharge from physical therapy. These patients were all treated at Therapeutic Associates - Cedar Hills Physical Therapy in Portland, Oregon. Methods. Objective measures (Therapeutic Associates Outcomes System Functional Index (TAOS),

  6. NREL is a national laboratory of the U.S. Department of Energy Office of Energy Efficiency & Renewable Energy

    E-print Network

    & Renewable Energy Operated by the Alliance for Sustainable Energy, LLC. This report is available at no cost from the National Renewable Energy Laboratory (NREL) at www.nrel.gov/publications. Contract No. DE-AC36 to Hydrocarbons R. Davis, L. Tao, E.C.D. Tan, M.J. Biddy, G.T. Beckham, and C. Scarlata National Renewable Energy

  7. Computational studies of guanine oxidation

    E-print Network

    Schlegel, H. Bernhard

    Prof. Richard Lord Prof. Xiaosong Li Prof. Peng Tao Prof. Jason Sonnenberg Prof. Barbara Munk Prof. Smriti Anand Dr. Jason Sonk Dr. Jia Zhou #12;Computational studies of guanine oxidation Prof. Cynthia,3 1Gedik et al. FASEB J. 2005, 19, 82. Collins et al. Free Radical Biol. Med. 2003, 34, 1089. 2Neeley

  8. Genomic DNA Extraction from Cells by Electroporation on an Integrated Microfluidic Platform

    E-print Network

    Lu, Chang

    -21 Chemical lysis methods are most commonly used for DNA extraction either on-chip22-27 or off-chip.28Genomic DNA Extraction from Cells by Electroporation on an Integrated Microfluidic Platform Tao. However, there has been no experimental confirmation on whether electrical lysis extracts genomic DNA from

  9. Mining Test Oracles of Web Search Engines Wujie Zheng1

    E-print Network

    Xie, Tao

    Mining Test Oracles of Web Search Engines Wujie Zheng1 , Hao Ma2 , Michael R. Lyu1 , Tao Xie3}@cse.cuhk.edu.hk, haoma@microsoft.com, xie@csc.ncsu.edu Abstract--Web search engines have major impact in people's everyday life. It is of great importance to test the retrieval effectiveness of search engines. However

  10. Improving the Prediction of the East Asian Summer Monsoon: New Approaches Nansen-Zhu International Research Centre, Institute of Atmospheric Physics, and Key Laboratory of Regional Climate-Environment for

    E-print Network

    2012 American Meteorological Society #12;then retreats south in the late summer and autumn. Meanwhile, and flood and drought disaster reduction. However, the skillful prediction of monsoons, particularly those atmosphere over the South China Sea, the monsoon trough, and the mei-yu front (Tao and Chen 1987; Ding

  11. Statistical Methods for Detecting Stellar Occultations by Kuiper Belt Objects

    E-print Network

    Rice, John

    Statistical Methods for Detecting Stellar Occultations by Kuiper Belt Objects: the Taiwanese-American Occultation Survey Chyng-Lan Liang John A. Rice Imke de Pater Charles Alcock§ Tim Axelrod¶ Andrew Wang Stuart Marshall September 3, 2002 Abstract The Taiwanese-American Occultation Survey (TAOS) will detect objects

  12. Cloud Detection over Snow and Ice Using MISR Data , Eugene E. Clothiaux

    E-print Network

    Yu, Bin

    Cloud Detection over Snow and Ice Using MISR Data Tao Shi , Bin Yu , Eugene E. Clothiaux , and Amy J. Braverman Abstract Clouds play a major role in Earth's climate and cloud detection prediction and global climate model studies. To advance the observational capabilities of detecting clouds

  13. MISR Cloud Detection over Ice and Snow Based on Linear Correlation Matching

    E-print Network

    Sekhon, Jasjeet S.

    MISR Cloud Detection over Ice and Snow Based on Linear Correlation Matching Tao Shi , Bin Yu , and Amy Braverman Abstract Cloud detection is a crucial step in any climate modelling or prediction data to retrieve or estimate the cloud height and hence cloud detection. However, cloud detection even

  14. Making Time-stepped Applications Tick in the Cloud

    E-print Network

    Keinan, Alon

    Making Time-stepped Applications Tick in the Cloud Tao Zou, Guozhang Wang, Marcos Vaz Salles · Iterative Graph Processing · Matrix Computation #12;Why Run Scientific Applications in the Cloud? · Elasticity · Cost Saving · Instant Availability 9 Avoid jobs queuing for days #12;What Does Cloud

  15. Scoping Plan Measures Implementation Timeline May 5, 2009

    E-print Network

    ARB 2010 2015 2.5 Regulation Tao Huai 24 Refinery Flare Recovery System Improvement I-4 C-155 ARB Refinery Regulations I-5 C-156 ARB, Local Air Districts Dec-10 2012 0.01 Regulation Reza Lorestany 26 GHG

  16. 26 CFR 301.7811-1 - Taxpayer assistance orders.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...determination of the NTA, the taxpayer is suffering or is about to suffer a significant...TAO. A finding that a taxpayer is suffering or about to suffer a significant...if a taxpayer is about to suffer or is suffering a significant hardship. A request...

  17. 26 CFR 301.7811-1 - Taxpayer assistance orders.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...determination of the NTA, the taxpayer is suffering or is about to suffer a significant...TAO. A finding that a taxpayer is suffering or about to suffer a significant...if a taxpayer is about to suffer or is suffering a significant hardship. A request...

  18. 26 CFR 301.7811-1 - Taxpayer assistance orders.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...determination of the NTA, the taxpayer is suffering or is about to suffer a significant...TAO. A finding that a taxpayer is suffering or about to suffer a significant...if a taxpayer is about to suffer or is suffering a significant hardship. A request...

  19. 26 CFR 301.7811-1 - Taxpayer assistance orders.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...determination of the NTA, the taxpayer is suffering or is about to suffer a significant...TAO. A finding that a taxpayer is suffering or about to suffer a significant...if a taxpayer is about to suffer or is suffering a significant hardship. A request...

  20. Tropical Atmosphere Ocean Project: El Nino and La Nina 3-D Visualizations

    NSDL National Science Digital Library

    Users can view a selection of animations of ocean surface temperature and dynamic height derived from data from the TAO/TRITON buoy array moored in the Pacific Ocean. The animations show temperature and surface topography variations consistent with the development of El Nino and La Nina events.

  1. 78 FR 14352 - Notice of Approved Class III Tribal Gaming Ordinances

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-05

    ...Santa Clara 190. Pueblo of Santo Domingo 191. Pueblo of Taos 192. Pueblo of Tesuque 193. Puyallup Tribe of Indians 194. Pyramid Lake Paiute Tribe 195. Quapaw Tribe of Indians 196. Quartz Valley Indian Community 197. Quechan Tribe of Fort Yuma...

  2. Uncertainty principles and vector quantization

    Microsoft Academic Search

    Yurii Lyubarskii; Roman Vershynin

    2010-01-01

    Abstract. An abstract form of the Uncertainty Principle set forth by Candes and Tao has found remarkable applications in the sparse approximation theory. This pa- per demonstates a new connection between the Uncertainty Principle and the vector quantization theory. We show that for frames in C, that satisfy the Uncertainty Principle, one can quickly convert every frame representation into a

  3. Uniform uncertainty principle for Bernoulli and subgaussian ensembles

    Microsoft Academic Search

    Shahar Mendelson; Alain Pajor; Nicole Tomczak-Jaegermann

    2006-01-01

    We present a simple solution to a question posed by Candes, Romberg and Tao on the uniform uncertainty principle for Bernoulli random matrices. More precisely, we show that a rectangular k*n random subgaussian matrix (with k < n) has the property that by arbitrarily extracting any m (with m < k) columns, the resulting submatrices are arbitrarily close to (multiples

  4. CIC ACADEMIC LEADERSHIP FELLOWS PURDUE UNIVERSITY

    E-print Network

    Ginzel, Matthew

    .T. Smith 2004-2005 Jay P. Gore Nancy S. Hewison Aditya P. Mathur Alastair M. Morrison Venetria K. Patton-1997 Wayne Dyksen Carolyn Perrucci Dave Petritz Dale Schunk 1997-1998 Eli Asem Carl Cowen Holly Mason Phil Mary A. Sadowski 2005-2006 Jeffrey T. Bolin Diane K. Denis Roseann M. Lyle Bernard Y. Tao Joseph Thomas

  5. Educational Software Engineering: Where Software Engineering, Education, and Gaming Meet

    E-print Network

    Xie, Tao

    Educational Software Engineering: Where Software Engineering, Education, and Gaming Meet Tao Xie and advocate the subfield of educational software engineering (i.e., software engineering for education), which develops software engineering technologies (e.g., software testing and analysis, software analytics

  6. Software Analytics in Practice Dongmei Zhang, Shi Han, Yingnong Dang, Jian-Guang Lou, Haidong Zhang, Microsoft Research Asia,

    E-print Network

    Xie, Tao

    Software Analytics in Practice Dongmei Zhang, Shi Han, Yingnong Dang, Jian-Guang Lou, Haidong Zhang, Microsoft Research Asia, China Tao Xie, University of Illinois at Urbana-Champaign, USA Abstract: Software analytics is to utilize data-driven approaches to enable software practitioners to perform data exploration

  7. Early Observations in the Taiwanese-American Occultation Survey

    Microsoft Academic Search

    C. Alcock; F. Bianco; M. Lehner; R. Dave; J. Giammarco; M. Schwamb; K. Cook; S. Marshall; I. de Pater; R. Porrata; J. Rice; J. Lissauer; T. Lee; S. K. King; A. Wang; S. Y. Wang; C. Y. Wen; W. P. Chen; W. Ip; Y. H. Chang; D. Kinoshita; H. C. Lin; S. Mondal; Z. W. Zhang; T. Axelrod; Y. I. Byun

    2005-01-01

    The Taiwanese-American Occultation Survey (TAOS) is a program dedicated to performing a survey of the size and number distribution for small bodies (< 10km) in the Kuiper Belt. These objects are too faint to be detected through traditional means, but can be observed via their occultations of background stars. This technique is challenging due to the low event rate, the

  8. American Studies Department Student Papers Collection Summary

    E-print Network

    Aspects of Colonial America" by Larry E. Myers Box 1 FF 15 "Hispanic Architecture of the Southwest" Joe D "The Changing Literary Movement" by Larry Wacker Box 1 FF 20 "Romantic Art in America, 1800 "Brady, Matthew" by Ron Watson Box 2 FF 7 "D. H. Lawrence in Taos" by Sally Armstrong Box 2 FF 8 "J. M

  9. JDF: Detecting Duplicate Bug Reports in Jazz Yoonki Song1

    E-print Network

    Xie, Tao

    JDF: Detecting Duplicate Bug Reports in Jazz Yoonki Song1 Xiaoyin Wang2,3 Tao Xie1 Lu Zhang2 number of existing bug reports. This paper presents JDF (representing Jazz Duplicate Finder), a tool that helps users to find potential duplicates of bug reports on Jazz, which is a team collaboration platform

  10. Using ACL2 to Verify Security Properties of Specification-based Intrusion Detection Systems

    E-print Network

    California at Davis, University of

    Using ACL2 to Verify Security Properties of Specification- based Intrusion Detection Systems Tao policy of systems. There are basically three different kinds of intrusion detection: Anomaly detection by a specific specification-based intrusion detection system. In this paper a hierarchical model is built

  11. Neuroscience Letters 366 (2004) 5862 Age-related effects of bilateral frontal eye fields lesions on rapid eye

    E-print Network

    Zhou, Yi-Feng

    Neuroscience Letters 366 (2004) 58­62 Age-related effects of bilateral frontal eye fields lesions on rapid eye movements during REM sleep in rhesus monkeys Shan Yua,b,1, Ning Liub,1, Tao Zengb,c, Shaohua Received 14 January 2004; received in revised form 7 April 2004; accepted 8 May 2004 Abstract Rapid eye

  12. Emphasis on Interpersonal Factors in a Dynamic Model of Relapse

    ERIC Educational Resources Information Center

    Witkiewitz, Katie; Marlatt, G. Alan

    2005-01-01

    This article presents comments on "Relapse Prevention Needs More Emphasis on Interpersonal Factors" by Stanton which is a comment on the original article "Relapse Prevention for Alcohol and Drug Problems: That Was Zen, This Is Tao" by Katie Witkiewitz and G. Alan Marlatt. In the current comment the authors of the original article respond to…

  13. 4388 IEEE TRANSACTIONS ON INFORMATION THEORY, VOL. 56, NO. 9, SEPTEMBER 2010 New Bounds for Restricted Isometry Constants

    E-print Network

    Cai, T. Tony

    isometry property, sparse signal recovery. I. INTRODUCTION COMPRESSED sensing aims to recover high-0854973. G. Xu was supported in part by the National 973 Project of China (No. 2007CB807902). T. T. Cai], and in Candès and Tao [9]. In [4], Caiet al. proved that stable recovery can be achieved when .1 In a recent

  14. Electrostatic Regulation of Genome Packaging in Human Hepatitis B Virus Zhen-Gang Wang,

    E-print Network

    Wu, Jianzhong

    Electrostatic Regulation of Genome Packaging in Human Hepatitis B Virus Tao Jiang, Zhen-Gang Wang, California ABSTRACT Hepatitis B virus (HBV) is a contagious human pathogen causing liver diseases-termini. INTRODUCTION Hepatitis B virus (HBV) is a pararetrovirus responsible for up to 80% of all cases

  15. Atmosphere Focus Team A Hazard Assessment from 11 Mars

    E-print Network

    Withers, Paul

    km that affect EDL and TAO including both fair-weather and dust storms · Hazard: That wind shear speed and long duration parachute descent is modified by dense moving, atmosphere · Wind drifts can (Region B) · Gone at night (Region D) · Convective Region, C , is marginally stable but becomes unstable

  16. 75 FR 67966 - Notice of a Project Waiver of Section 1605 (Buy American Requirement) of the American Recovery...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-04

    ...and in the proper form or specification as specified in the project...revise their standards and specifications, institute a new bidding...which is to create or retain jobs. The Region 6 Water Quality...to meet Taos' technical specifications, a waiver from the Buy...

  17. Reliable Peak Selection for Multisample Analysis with Comprehensive Two-Dimensional Chromatography

    E-print Network

    Reichenbach, Stephen E.

    Biofuels and Co-Products Research Unit, USDA-ARS, Eastern Regional Research Center, Wyndmoor, Pennsylvania Tao*, University of Nebraska - Lincoln, Lincoln, Nebraska 68588-0115, United States Sustainable 19038-8598, United States § Dipartimento di Scienza e Tecnologia del Farmaco, Universita degli Studi di

  18. Blood Impedance Characterization from Pulsatile Measurements School of Information Technology

    E-print Network

    Adler, Andy

    Blood Impedance Characterization from Pulsatile Measurements Tao Dai School of Information of blood excluding the contributions from surround- ing tissues, based on analysis of the pulsatile MHz. The finger is modeled as three parts: arterial blood, surrounding tissues and incremental in

  19. In Vivo Blood Characterization from Bioimpedance Spectroscopy of Blood

    E-print Network

    Adler, Andy

    In Vivo Blood Characterization from Bioimpedance Spectroscopy of Blood Pooling Tao Dai Department@sce.carleton.ca Abstract Characterization of blood impedance properties is important to estimate clinical diagnos- tic in the measurement field, rather than the blood individually. This paper describes a novel in vivo measurement

  20. PASSIVE SYSTEM ACCIDENT SCENARIO ANALYSIS BY Francesco Di Maio1

    E-print Network

    Paris-Sud XI, Université de

    PASSIVE SYSTEM ACCIDENT SCENARIO ANALYSIS BY SIMULATION Francesco Di Maio1 , Enrico Zio1,2 , Tao (RHRs), High Temperature Gas- Cooled Reactor ­ Pebble Bed Modular (HTR-PM), Scenario Analysis, Monte of the reactor core after shut-down. A thermal-hydraulic (T-H) model for scenario analysis has been implemented

  1. This paper will appear at the 22nd USENIX Security Symposium in Washington, D.C., August 2013. The Velocity of Censorship: High-Fidelity Detection of Microblog Post

    E-print Network

    Crandall, Jedidiah R.

    . The Velocity of Censorship: High-Fidelity Detection of Microblog Post Deletions Tao Zhu zhutao777@gmail for exercising internal censorship, to comply with Chinese government requirements. This research seeks to quantify the mechanisms of this censorship: how fast and how comprehensively posts are deleted. Our

  2. Active Window Oriented Dynamic Video Retargeting

    E-print Network

    Jia, Jiaya Leo

    .g., most of the players in sport games always do not face to the camera directly), the locationsActive Window Oriented Dynamic Video Retargeting Chenjun Tao, Jiaya Jia, Hanqiu Sun Department playing high-resolution videos on mobile devices with a limited screen size, a commonly arisen but seldom

  3. Probing 3-ssDNA Loop Formation in E. coli RecBCD/RecBCDNA Complexes Using Non-natural

    E-print Network

    Lohman, Timothy M.

    for "Chi" Recognition Complexes C. Jason Wong1 , Rachel L. Rice1 , Nathan A. Baker1 , Tao Ju2 and Timothy M with heli- case activity result in genetic disorders such as the Werner syndrome5,6 and the Bloom syndrome.7

  4. REMARKS ON THE CAUCHY PROBLEM FOR THE ONE-DIMENSIONAL QUADRATIC (FRACTIONAL) HEAT EQUATION

    E-print Network

    Boyer, Edmond

    REMARKS ON THE CAUCHY PROBLEM FOR THE ONE-DIMENSIONAL QUADRATIC (FRACTIONAL) HEAT EQUATION LUC quadratic (fractional) heat equation: ut = D2 x u u2 , t (0, T), x R or T, with 0 introduced by Bejenaru-Tao [1] for a one-dimensional quadratic Schr¨odinger equation. This approach is based

  5. Prospects for a Muon Collider Kirk T. McDonald

    E-print Network

    McDonald, Kirk

    , Vernon D. Barger 4 , Odette Benary 5 , Scott Berg 6 , Michael S. Berger 6 , S. Alex Bogacz 7 , T. Bolton H. Geer 1 , Ilya F. Ginzburg 16 , Michael A. Green 9 , John F. Gunion 17 , Ramesh Gupta 9 , Tao Han , Hiromi Okamoto 21 , Yasar Onel 22 , Robert B. Palmer 13 , Zohreh Parsa 13 , Jack M. Peterson 9 , Yuriy

  6. Status of Muon Collider Research and Development and Future Plans

    E-print Network

    McDonald, Kirk

    , Odette Benary 5 , Scott Berg 6 , Michael S. Berger 6 , S. Alex Bogacz 7 , T. Bolton 8 , Shlomo Caspi 9 F. Ginzburg 16 , Michael A. Green 9 , John F. Gunion 17 , Ramesh Gupta 9 , Tao Han 17 , Katherine C , Yasar Onel 22 , Robert B. Palmer 13 , Zohreh Parsa 13 , Jack M. Peterson 9 , Yuriy Pischalnikov 11

  7. FermilabPUB98/179 Status of Muon Collider Research and

    E-print Network

    McDonald, Kirk

    . Balbekov, 1 Vernon D. Barger, 4 Odette Benary, 5 Scott Berg, 6 Michael S. Berger, 6 S. Alex Bogacz, 7 T Stephen H. Geer, 1 Ilya F. Ginzburg, 16 Michael A. Green, 9 John F. Gunion, 17 Ramesh Gupta, 9 Tao Han, 17 Yasar Onel, 22 Robert B. Palmer, 13 Zohreh Parsa, 13 Jack M. Peterson, 9 Yuriy Pischalnikov, 11 Milorad

  8. We Shared the Same Chapter: Collaboration, Learning, and Transformation from the 2008 Subsistence, the Environment, and Community Well-Being Native Youth Exchange in Old Harbor, Alaska Project

    ERIC Educational Resources Information Center

    Richmond, Laurie; Di Piero, Daniela; Espinoza, Flowers; Simeonoff, Teacon; Faraday, Margaret

    2010-01-01

    On a small island belonging to the Alutiiq people of Old Harbor, 11 people sat around a campfire. Two community leaders, a nonprofit organizer, an academic scholar, a native filmmaker, and six young people from the Indian reservation of Taos Pueblo in New Mexico gathered after a day of interacting with Old Harbor residents--fishing, hunting and…

  9. The Role of Discursive Resources in Science Talk

    ERIC Educational Resources Information Center

    Hsu, Pei-Ling

    2013-01-01

    Tao, Oliver, and Venville's paper addresses a debate between two hypotheses of children's development of conceptual understandings of the Earth. The authors aim to investigate whether culture influences students' conceptions of the Earth. However, one questionable assumption shared among conception and conceptual change studies is that researchers…

  10. A sex-ratio Meiotic Drive System in Drosophila simulans. II: An X-linked Distorter

    E-print Network

    Hartl, Daniel L.

    the evolutionary forces shaping the meiotic behavior of the sex chromosomes. Here we characterize a sexA sex-ratio Meiotic Drive System in Drosophila simulans. II: An X-linked Distorter Yun Tao1 of heteromorphic sex chromosomes creates a genetic condition favoring the invasion of sex-ratio meiotic drive

  11. SUBMITTED TO IEEE TVCG 1 Vectorizing Cartoon Animations

    E-print Network

    Martin, Ralph R.

    and animation styles, plots, and soundtracks. Currently, such cultural heritage is preserved and disseminated as digital video after conversion from film using telecine. Such video is in raster format. However, animatedSUBMITTED TO IEEE TVCG 1 Vectorizing Cartoon Animations Song-Hai Zhang1 Tao Chen1 Yi-Fei Zhang1 Shi

  12. A study of the effect of boundary conditions and drag force on the diffusion of a Newtonian fluid through a non-linearly elastic solid

    E-print Network

    Prasad, Sharat Chand

    2002-01-01

    with the experiments (whether it is the saturation boundary condition used by Rajagopal, Wineman and Gandhi, the traction splitting boundary condition used by Rajagopal and Tao, the natural boundary condition used by Baek and Srinivasa, or the fact that the chemical...

  13. Graduate College Committees 20102011 EXECUTIVE COMMITTEE CURRICULUM COMMITTEE FACULTY AND STUDENT ISSUES COMMITTEE

    E-print Network

    Cho, Hokwon

    ) Gail Sammons (Hotel) Neil Opfer (Construction Management) Salley Sawyer (Ed Outreach) Janet WhiteSommer (Communication Studies) Tom Bean (C & I) Reza Torkzadeh (Business) Zhongbo Yu (Geoscience) Ying Tao Jiang (Elec Gordon (GPSA) Murray Millar (Psychology) P.G. Schrader (Curriculum & Instruction) Sean Clark (Film) Tom

  14. Using DNA Microarray to Identify Sp1 as a Transcriptional Regulatory Element of Insulin-like Growth Factor-1 in Cardiac Muscle Cells

    E-print Network

    Kibler, Dennis F.

    in the promoter region. Insulin-like growth factor 1 (IGF-1) modulates myocardial gene expression and regulates-like Growth Factor-1 in Cardiac Muscle Cells Tao Li1 , Yung-Hsiang Chen1,2 , Tsun-Jui Liu1,2 , Jia Jia1 Chemistry, Physiology and Biophysics, Center for Cardiovascular Hormone Research, University of California

  15. Proceedings of Student-Faculty Research Day, CSIS, Pace University, May 3rd Advanced Integrated Syntax and Semantic Validation for Services Computing

    E-print Network

    Tappert, Charles

    Integrated Syntax and Semantic Validation for Services Computing Amer Ali and Lixin Tao Seidenberg School are critical to the correct service transaction specification and service integration based on existing distributed and heterogeneous computing services. This research proves that the current industry practices

  16. VOLUME 76, NUMBER 11 P H Y S I C A L R E V I E W L E T T E R S 11 MARCH 1996 Threshold Dynamics of Singular Gravity-Capillary Waves

    E-print Network

    Lathrop, Daniel P.

    of Singular Gravity-Capillary Waves Christopher L. Goodridge, W. Tao Shi, and Daniel P. Lathrop* Department and capillary waves. Gravity and capillary waves are defined from the dispersion relation for infinite depth frequency capillary (v . v0) wave ranges. Low frequency (gravity) waves still experience capillary effects

  17. THE ASTROPHYSICAL JOURNAL SUPPLEMENT SERIES, 115:185202, 1998 April 1998. The American Astronomical Society. All rights reserved. Printed in U.S.A.(

    E-print Network

    Dietrich, Matthias

    . K. HONEYCUTT,15 K. HORNE,6 J. P. HUCHRA,16 S. KASPI,17 M. KU MMEL,1 K. M. LEIGHLY,18 D. C. LEONARD,5,29 S. A. SNEDDEN,11 S. SOUNDARARAJAPERUMAL,14 G. M. STIRPE,30 J. TAO,24 G. W. TURNER,15 R. M. WAGNER

  18. What do you love about the International Learning Community at UW-Madison? "Choosing to live in the ILC was by far the best decision I could have made for my college career. Not

    E-print Network

    Wisconsin at Madison, University of

    Mukwonago, WI "Joining ILC has allowed me to meet many interesting people including different cultures. I to taste different cultural foods." ­ Sheng Yang, Sophomore, majoring in Art History, from Stevens Point." ­ Rui Tao, Sophomore, majoring in Food Science, from Shanghai, China "The ILC is a very tight knit

  19. Construction of a Large Class of Deterministic Sensing Matrices that Satisfy a Statistical Isometry Property

    Microsoft Academic Search

    A. Robert Calderbank; Stephen D. Howard; Sina Jafarpour

    2009-01-01

    Compressed Sensing aims to capture attributes of a signal using very few measurements. The Restricted Isometry Property is the condition that the sensing matrix acts as as near isometry on all k-sparse signals. Candes and Tao showed that this condition is sufficient for sparse reconstruction and that random matrices, where the entries are generated by an iid Gaussian or Bernoulli

  20. A sublinear algorithm for sparse reconstruction with ?2\\/?2 recovery guarantees

    Microsoft Academic Search

    Robert Calderbank; Stephen Howard; Sina Jafarpour

    2009-01-01

    Compressed sensing aims to capture attributes of a sparse signal using very few measurements. Candes and Tao showed that sparse reconstruction is possible if the sensing matrix acts as a near isometry on all k-sparse signals. This property holds with overwhelming probability if the entries of the matrix are generated by an iid Gaussian or Bernoulli process. There has been

  1. Watch It

    ERIC Educational Resources Information Center

    Bolch, Matt

    2008-01-01

    For the school chief information officer (CIO), safeguarding students and facilities is as much a part of the job description as keeping the data networks running and the servers protected from hackers. This article describes how two districts, Miami-Dade County Public Schools and Taos Municipal Schools, secured their surveillance systems. The…

  2. Molecular Beacons DOI: 10.1002/anie.201209440

    E-print Network

    Tan, Weihong

    and Gene Therapy** Tao Chen, Cuichen Sam Wu, Elizabeth Jimenez, Zhi Zhu, Joshua G. Dajac, Mingxu You, Da facilitated the development of disease diagnosis and gene therapy. For example, both linear[2] and hairpin[3 for gene therapy.[5a] The advantages of nucleic acid probes lie in the simplicity of their synthesis

  3. Different Perspectives of Cultural Mediation: Implications for the Research Design on Studies Examining Its Effect on Students' Cognition

    ERIC Educational Resources Information Center

    Teo, Tang Wee

    2013-01-01

    In this forum, I extend Tao, Oliver, and Venville's paper "Chinese and Australian children's understanding of the earth: a cross cultural study of conceptual development" to discuss the different views on culture and cultural mediation. I tease out nuances in the viewpoints to suggest three ways to theoretically frame studies examining cultural…

  4. Introduce New Faculty Chun Han-Weill Introduce New Employees NONE

    E-print Network

    Keinan, Alon

    Student Award-$20,000 Ebere Joseph-Nicholson Douglas Award Angelina Noriega-Brown Douglas Award Tao Sun Society for Microbial Ecology(ISME) Young Investigator Award Kelly Liu Named by a Cornell Merrill-Lis CALS Outstanding Teaching Award Joel Brown-Garcia CALS Outstanding Teaching Award-OUB Carolyn Fisher

  5. ``FROM DATABASES TO VISUALISATION'' Providing a User Friendly

    E-print Network

    Ward, Matthew

    Geological Block Models Tao Lin 1 , Matthew O. Ward 2 , Bill Power 3 , and Danielle Landy 1 Abstract block models derived by examining data from diverse sources; these data sources include magnetic data, gravity data, and drill hole data. The creation process of a geological block model is difficult

  6. Proof-of-Concept Development of a Microfabricated Tuning-Fork Based

    E-print Network

    Fay, Noah

    -products in drinking water Prof. Paul Westerhoff ASU Civil and Environmental Engineering Prof. Nongjian Tao ASU............................................................................................................. 7 Liquid-Liquid Extraction of THMs for Chlorination Tests Table 3.1 List of selected polymers tested for their ability to detect chloroform on a modified QTF

  7. AUTOMATIC ROAD EXTRACTION FROM DENSE URBAN AREA BY INTEGRATED PROCESSING OF HIGH RESOLUTION IMAGERY AND LIDAR DATA

    E-print Network

    Salvaggio, Carl

    AND LIDAR DATA Xiangyun Hu C. Vincent Tao Yong Hu Geospatial Information and Communication Technology Lab, Multisensor, High Resolution, LIDAR, Urban, Contextual ABSTRACT: Automated and reliable 3D city model on the integrated processing of high resolution imagery and LIDAR (LIght Detection And Ranging) data for automatic

  8. A Decentralized Sleep Mechanism in Heterogeneous Cellular Networks with QoS Constraints

    E-print Network

    Tao, Meixia "Melissa"

    1 A Decentralized Sleep Mechanism in Heterogeneous Cellular Networks with QoS Constraints Ping Ren and Meixia Tao, Senior Member, IEEE Abstract--We introduce a sleep mechanism for energy effi- ciency band. The strategy is to put high-power macro base stations into sleep mode and offload the users

  9. Racing Multi-Objective Selection Probabilities G. Marceau-Caron1,2

    E-print Network

    Boyer, Edmond

    Systems, Rungis, France 2 TAO Project, INRIA Saclay & LRI Paris-Sud University, Orsay, France {marc the decision maker to define some pref- erences about how to handle them, through some statistics (e.g., mean. Approximating these statistics requires repeated samplings of the population, drastically increasing the overall

  10. Remarkable charge-trapping efficiency of the memory device with (TiO2)0.8(Al2O3)0.1 composite charge-storage dielectric

    NASA Astrophysics Data System (ADS)

    Jiang, K.; Ou, X.; Lan, X. X.; Cao, Z. Y.; Liu, X. J.; Lu, W.; Gong, C. J.; Xu, B.; Li, A. D.; Xia, Y. D.; Yin, J.; Liu, Z. G.

    2014-06-01

    A memory device p-Si/SiO2/(TiO2)0.8(Al2O3)0.1(TAO-81)/Al2O3/Pt was fabricated, in which a composite of two high-k dielectrics with a thickness of 1 nm was employed as the charge-trapping layer to enhance the charge-trapping efficiency of the memory device. At an applied gate voltage of ±9 V, TAO-81 memory device shows a memory window of 8.83 V in its C-V curve. It also shows a fast response to a short voltage pulse of 10-5 s. The charge-trapping capability, the endurance, and retention characteristics of TAO-81 memory device can be improved by introducing double TAO-81 charge-trapping layers intercalated by an Al2O3 layer. The charge-trapping mechanism in the memory device is mainly ascribed to the generation of the electron-occupied defect level in the band gap of Al2O3 induced by the inter-diffusion between TiO2 and Al2O3.

  11. Large Gate Modulation in the Current of a Room Temperature Single Molecule Transistor

    E-print Network

    Zhang, Yanchao

    , Xiaoyin Xiao, Xiaomei Yang, Ling Zang,*, and Nongjian Tao*, The Center for Solid State Electronics Research, Arizona State UniVersity, Tempe, Arizona 85287, and Department of Chemistry and Biochemistry is applied between the source and a gate in the electrolyte.8 Since the gate voltage falls across the double

  12. Grover

    USGS Multimedia Gallery

    Grover was built in just four months in 1971 by the USGS Astrogeology Research Program (called the Branch of Astrogeology at the time) and used to training Apollo 15-17 astronauts at the Cinder Lakes training ground near Flagstaff, in California's Mojave Desert, and in the Rio Grande gorge near Taos...

  13. Evidence of lightning NOx and convective transport of pollutants in satellite observations over North America

    E-print Network

    Chance, Kelly

    North America Yunsoo Choi,1 Yuhang Wang,1 Tao Zeng,1 Randall V. Martin,2 Thomas P. Kurosu,3 and Kelly January 2005. [1] Column observations of NO2 by GOME and CO by MOPITT over North America and surrounding transport of pollutants in satellite observations over North America, Geophys. Res. Lett., 32, L02805, doi

  14. Ultralow-loss polycrystalline silicon waveguides and high uniformity 1x12 MMI fanout for 3D

    E-print Network

    Chen, Ray

    . Chen,1 1 Microelectronics Research Center, Department of Electrical and Computer Engineering 2nd ed. (Kluwer, 1998). 7. S. Zhu, Q. Fang, M. B. Yu, G. Q. Lo, and D. L. Kwong, "Propagation losses. Q. Fang, J. F. Song, S. H. Tao, M. B. Yu, G. Q. Lo, and D. L. Kwong, "Low loss (approximately 6.45d

  15. "WhenIwasfiveyearsold,mymotheralwaystoldme thathappinesswasthekeytolife.WhenIwenttoschool,they

    E-print Network

    Fernandez, Eduardo

    .WhenIwenttoschool,they askedmewhatIwantedtobewhenIgrewup.Iwrotedown `happy,The Practice Dec. 4 & 8, 2012 | Feb. 26, 2013 Apr. 20 & 23, 2013 Happiness: MakingYour Heartbeats CountTaoTe Ching, to guide us along the healing path of endless compassion. A simple method of meditation helping

  16. Killing Mosquitoes and Keeping Practice: Teacher Education as Sustaining Paradox

    ERIC Educational Resources Information Center

    Keiser, David Lee

    2013-01-01

    The moral and ethical charge of teaching and teacher education includes sustaining equanimity and paradox, and maintaining poise amongst contradicting policies and interests. This paper draws upon the wisdom of the Tao Te Ching to address some paradoxes in education and teacher preparation. Specifically, the article looks at four chapters of the…

  17. Statistical Validation of Compound Structure-Selectivity Relationship Using NCI Cancer Database

    E-print Network

    Li, Jing

    1 Statistical Validation of Compound Structure-Selectivity Relationship Using NCI Cancer Database Jing Li 1 Chris Benner 2 Tao Jiang 3 Yingyao Zhou 4 Keywords: structure-selectivity relationship, structure-activity relationship, compound fingerprint, growth inhibition, cancer cell line. Abstract

  18. THE JOURNAL OF CHEMICAL PHYSICS 135, 094304 (2011) "Adiabatic-hindered-rotor" treatment of the parahydrogen-water complex

    E-print Network

    Le Roy, Robert J.

    THE JOURNAL OF CHEMICAL PHYSICS 135, 094304 (2011) "Adiabatic-hindered-rotor" treatment of the parahydrogen-water complex Tao Zeng,1 Hui Li,2 Robert J. Le Roy,1 and Pierre-Nicholas Roy1,a) 1 Department 1 September 2011) Inspired by a recent successful adiabatic-hindered-rotor treatment

  19. Isometric Cycles, Cutsets, and Crowning

    E-print Network

    Jiang, Tao

    Isometric Cycles, Cutsets, and Crowning of Bridged Graphs Tao Jiang,1 Seog-Jin Kim,2 and Douglas B S in a bridged graph G induces a connected subgraph. We introduce a ``crowning'' construction to enlarge Keywords: bridged graph; chordal graph; cutset; isometric cycle; convex subgraph; crowning 1. INTRODUCTION

  20. L'hebdo de l'cole normale suprieure juin-juillet2006 Modlisationetmthodesstatistiquesensciencessociales.

    E-print Network

    Gutkin, Boris

    Médée de Corneille les 26 et 27 juin dans la cour de l'École normale supérieure, 45,rue d'Ulm,Paris 5e-emitted gravity waves :a challenge for theorists ». Mardi 27 juin, 14h30, salle 316, 3e étage, département TAO

  1. WormFarm: a quantitative control and measurement device toward automated Caenorhabditis elegans aging analysis

    E-print Network

    Huang, Yanyi

    aging analysis Bo Xian,1,3 * Jie Shen,2 * Weiyang Chen,1 * Na Sun,1,3 Nan Qiao,1,3 Dongqing Jiang,2 Tao model organism for studying the basic mechanisms of aging. Progress has been limited, however reporter in conjunction with WormFarm, we report an age-associated decrease in fluorescent intensity of GFP

  2. IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS--II: ANALOG AND DIGITAL SIGNAL PROCESSING, VOL. 47, NO. 7, JULY 2000 629 Adaptive Digital Correction of Analog Errors

    E-print Network

    Moon, Un-Ku

    Wiesbauer, Member, IEEE, Tao Sun, Member, IEEE, Un-Ku Moon, Senior Member, IEEE, John T. Stonick, Member Technologies' Design Center, Villach, Austria. T. Sun is with National Semiconductor Company, Santa Clara, CA-line correction, the effects of temperature varia- tions, changes in process parameters, as well as of aging

  3. Distance Metric Learning under Covariate Shift , Xiaochuan Ni2

    E-print Network

    Yang, Qiang

    Distance Metric Learning under Covariate Shift Bin Cao1 , Xiaochuan Ni2 , Jian-Tao Sun2 , Gang Wang change due to the changing environment [Pan et al., 2008]. In these sit- uations, the distance metric, for the test data, the second dimension (y-axis) contains more discriminative information. Thus, the metric

  4. Tuesday, August 16, 2011 McKnight Hall

    E-print Network

    Xie,Jiang (Linda)

    . Spooner College of Education Dr. Anthony B. (Barry) Wilkinson Department of Computer Science Faculty. Susan K. Johnson Department of Psychology Dr. Tao-Hsien Dolly King Department of Finance Dr. Janet E. Edward B. Stokes Department of Electrical and Computer Engineering Dr. William J. Tolone Department

  5. Ontology-Based Categorization of Web Services with Machine Adam Funk, Kalina Bontcheva

    E-print Network

    Maynard, Diana

    ://www.oasis-open.org/committees/ uddi-spec/doc/tcspecs.htm 2 http://demo.service-finder.eu/ 3 http://www.tao-project.eu/ with semi batches of these data to the Automatic Annotator (AA), which pro- cesses them using information extraction

  6. Recursive Turtle Programs and Iterated Affine Transformations

    E-print Network

    Schaefer, Scott

    Recursive Turtle Programs and Iterated Affine Transformations Tao Ju*, Scott Schaefer, Ron Goldman of equivalence between the class of fractals created by Recursive Turtle Programs (RTP) and Iterated Affine, turtle graphics 1 Introduction In computer graphics, there are several different methods for generating 2

  7. Philosophy Department Electives Fall 2004 [Full course descriptions, with readings and requirements below

    E-print Network

    Huang, Jianyu

    below] PL 193 01 Chinese Classical Philosophy: Confucianism, Taoism, and Buddhism Frank Soo TTh 10: Confucianism, Taoism, and Buddhism. Emphasizing social harmony and order, Confucianism deals mainly with human this balance and harmony: Tao. Synthesized as soon as it arrived in China from India, Chinese Buddhism teaches

  8. Cultural Issues of School Dropouts in Hong Kong

    ERIC Educational Resources Information Center

    Lau, Yuk King; Tsang, Bill Y. P.; Kwok, Diana K.

    2007-01-01

    Despite the 150 years of British colonial governance in Hong Kong, Chinese collectivist culture continues to be a dominant source of influence in the learning context of students (Cheng, 1998; Salili, Lai and Leung, 2004; Tao and Hong, 2000), placing a great emphasis on education and effort (Salili and Lai, 2003). Education is viewed as the…

  9. Slightly beyond Turing's computability for studying genetic programming

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    Paris-Sud XI, Université de

    Slightly beyond Turing's computability for studying genetic programming Olivier Teytaud TAO, INRIA programming (GP), we study iterative algorithms for non-computable tasks and compare them to naive models are not computable. However, in practice, many people work on designing programs for solving non-computable tasks

  10. OCSOY ET AL. VOL. 7 ' NO. 10 ' 89728980 ' 2013 www.acsnano.org

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    Tan, Weihong

    Arslan Ocsoy, Sanju Kunwar, Tao Chen,, Mingxu You,, and Weihong Tan,,* Center for Research at the Bio/Nano decades, the disease has also been managed using copper (Cu) bacteri- cides, which have enhanced to copper.6 Disease management technologies, such as bacteriophages and systemic acquired resistance (SAR

  11. Comparing Website Fingerprinting Attacks and Defenses Cheriton School of Computer Science

    E-print Network

    Goldberg, Ian

    Comparing Website Fingerprinting Attacks and Defenses Tao Wang Cheriton School of Computer Science University of Waterloo Ian Goldberg Cheriton School of Computer Science University of Waterloo Abstract--Website clients who use anonymity technologies such as Tor are susceptible to website fingerprinting attacks

  12. WiZi-Cloud: Application-transparent Dual ZigBee-WiFi Radios for Low Power Internet Access

    E-print Network

    Noubir, Guevara

    WiZi-Cloud: Application-transparent Dual ZigBee-WiFi Radios for Low Power Internet Access Tao Jin1 in depleting the mobile phone's battery in a very short time. We propose WiZi- Cloud, a system that utilizes a dual WiFi-ZigBee radio on mobile phones and Access Points, supported by WiZi-Cloud protocols

  13. A mass-limited Sn target irradiated by dual laser pulses for an EUVL , M.S.Tillack1, 2

    E-print Network

    Najmabadi, Farrokh

    A mass-limited Sn target irradiated by dual laser pulses for an EUVL source Y.Tao*1, 2 , M simultaneously observed from plasma driven by a dual-pulse as compared with that of a single pulse. Thin Sn coating were investigated as a form of mass-limited target. It was found that the higher ion energy

  14. Safety-Ensured Coordination of Networked Medical Devices in MDPnP

    E-print Network

    Hu, Fei

    to generate medical errors [2]. As revealed in [2], medical errors are the leading cause of death and injury the human error-induced ac- cidents. This increasing demand has led to the establishment of the MedicalSafety-Ensured Coordination of Networked Medical Devices in MDPnP Tao Li, and Jiannong Cao

  15. This article was downloaded by:[University of Michigan] On: 25 February 2008

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    Rosenberg, Noah

    This article was downloaded by:[University of Michigan] On: 25 February 2008 Access Details. Rosenberg abc ; Randa Tao b a Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA b Center for Computational Medicine and Biology, University of Michigan, Ann Arbor, Michigan, USA c

  16. Enhanced dispersion analysis of borehole array sonic measurements with amplitude and phase estimation method

    E-print Network

    Torres-Verdín, Carlos

    estimation method Wei Li* , Rui Guo, Guo Tao, and Hua Wang, State Key Lab of Petroleum Resource, The University of Texas at Austin Summary We introduce a new non-parametric matched-filterbank spectral estimator, referred to as Amplitude and Phase Estimation (APES), to perform dispersion analysis of borehole array

  17. Processing Landsat TM Data Using Complex-Valued NRBF Neural Network

    E-print Network

    Michel, Howard E.

    Processing Landsat TM Data Using Complex- Valued NRBF Neural Network Xiaoli Tao Howard E. Michel classification technique -- a Complex-Valued Normalized Radial Basis Function (NRBF) neural network classifier. Complex-valued weights are used in the supervised learning part of NRBF neural networks. Different from

  18. How Proteins Search for Their Specific Sites on DNA: The Role of DNA Conformation

    E-print Network

    Minnesota, University of

    How Proteins Search for Their Specific Sites on DNA: The Role of DNA Conformation Tao Hu,* A. Yu have identified a wealth of new different scaling regimes. We also found the maximal possible deceleration of the reaction. INTRODUCTION The problem Imagine that while you are reading these lines a l

  19. THE TAIWAN-AMERICAN OCCULTATION SURVEY PROJECT STELLAR VARIABILITY. I. DETECTION OF LOW-AMPLITUDE {delta} SCUTI STARS

    SciTech Connect

    Kim, D.-W.; Protopapas, P.; Alcock, C.; Wright, N. J.; Bianco, F. B.; Lehner, M. J. [Harvard Smithsonian Center for Astrophysics, Cambridge, MA 02138 (United States); Byun, Y.-I. [Department of Astronomy, Yonsei University, Seoul 120-749 (Korea, Republic of); Kyeong, J.; Lee, B.-C. [Korea Astronomy and Space Science Institute, Daejeon 305-348 (Korea, Republic of); Axelrod, T. [Steward Observatory, 933 North Cherry Avenue, Room N204 Tucson, AZ 85721 (United States); Chen, W.-P.; Lin, H.-C. [Institute of Astronomy, National Central University, No. 300, Jhongda Rd, Jhongli City, Taoyuan County 320, Taiwan (China); Coehlo, N. K.; Rice, J. A. [Department of Statistics, University of California Berkeley, 367 Evans Hall, Berkeley, CA 94720 (United States); Cook, K. H.; Marshall, S. L. [Institute for Geophysics and Planetary Physics, Lawrence Livermore National Laboratory, Livermore, CA 94550 (United States); Dave, R. [Initiative in Innovative Computing, School of Engineering and Applied Sciences, Harvard, Cambridge, MA 02138 (United States); King, S.-K.; Lee, T. [Institute of Astronomy and Astrophysics, Academia Sinica, P.O. Box 23-141, Taipei 106, Taiwan (China); Porrata, R. [Department of Astronomy, University of California Berkeley, 601 Campbell Hall, Berkeley, CA 94720 (United States)] (and others)

    2010-02-15

    We analyzed data accumulated during 2005 and 2006 by the Taiwan-American Occultation Survey (TAOS) in order to detect short-period variable stars (periods of {approx}<1 hr) such as {delta} Scuti. TAOS is designed for the detection of stellar occultation by small-size Kuiper Belt Objects and is operating four 50 cm telescopes at an effective cadence of 5 Hz. The four telescopes simultaneously monitor the same patch of the sky in order to reduce false positives. To detect short-period variables, we used the fast Fourier transform algorithm (FFT) in as much as the data points in TAOS light curves are evenly spaced. Using FFT, we found 41 short-period variables with amplitudes smaller than a few hundredths of a magnitude and periods of about an hour, which suggest that they are low-amplitude {delta} Scuti stars. The light curves of TAOS {delta} Scuti stars are accessible online at the Time Series Center Web site (http://timemachine.iic.harvard.edu)

  20. This content has been downloaded from IOPscience. Please scroll down to see the full text. Download details

    E-print Network

    Wang, Zhong L.

    triboelectric surfaces varies periodically, driving the inductive charges back and forth between the two that terms and conditions apply. A power-transformed-and-managed triboelectric nanogenerator and its-transformed-and-managed triboelectric nanogenerator and its applications in a self-powered wireless sensing node Wei Tang1 , Tao Zhou1