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  1. A musculoskeletal model of low grade connective tissue inflammation in patients with thyroid associated ophthalmopathy (TAO): the WOMED concept of lateral tension and its general implications in disease

    PubMed Central

    Moncayo, Roy; Moncayo, Helga

    2007-01-01

    Background Low level connective tissue inflammation has been proposed to play a role in thyroid associated ophthalmopathy (TAO). The aim of this study was to investigate this postulate by a musculoskeletal approach together with biochemical parameters. Methods 13 patients with TAO and 16 controls were examined. Erythrocyte levels of Zn, Cu, Ca2+, Mg, and Fe were determined. The musculoskeletal evaluation included observational data on body posture with emphasis on the orbit-head region. The angular foot position in the frontal plane was quantified following gait observation. The axial orientation of the legs and feet was evaluated in an unloaded supine position. Functional propioceptive tests based on stretch stimuli were done by using foot inversion and foot rotation. Results Alterations in the control group included neck tilt in 3 cases, asymmetrical foot angle during gait in 2, and a reaction to foot inversion in 5 cases. TAO patients presented facial asymmetry with displaced eye fissure inclination (mean 9.1°) as well as tilted head-on-neck position (mean 5.7°). A further asymmetry feature was external rotation of the legs and feet (mean 27°). Both foot inversion as well as foot rotation induced a condition of neuromuscular deficit. This condition could be regulated by gentle acupressure either on the lateral abdomen or the lateral ankle at the acupuncture points gall bladder 26 or bladder 62, respectively. In 5 patients, foot rotation produced a phenomenon of moving toes in the contra lateral foot. In addition foot rotation was accompanied by an audible tendon snapping. Lower erythrocyte Zn levels and altered correlations between Ca2+, Mg, and Fe were found in TAO. Conclusion This whole body observational study has revealed axial deviations and body asymmetry as well as the phenomenon of moving toes in TAO. The most common finding was an arch-like displacement of the body, i.e. eccentric position, with foot inversion and head tilt to the contra lateral side and tendon snapping. We propose that eccentric muscle action over time can be the basis for a low grade inflammatory condition. The general implications of this model and its relations to Zn and Se will be discussed. PMID:17319961

  2. Selenium supplementation in thyroid associated ophthalmopathy: an update

    PubMed Central

    Dharmasena, Aruna

    2014-01-01

    The therapeutic effect of selenium (Se) has already been proven in thyroid disease and thyroid associated ophthalmopathy (TAO). In spite of clear scientific proof of its benefits in TAO, there appears to be no clear agreement among the clinicians regarding its optimum dose, duration of the treatment, efficacy and safety to date. In this review, the author summarises the findings of 135 English language articles published on this subject over the past four decades from 1973 to 2013. The regulation and metabolism of thyroid hormones require a steady supply of Se and recent studies have revealed several possible mechanisms by which Se improves the severity of thyroid disease and TAO. These mechanisms include 1) inhibitory effect of HLA-DR molecule expression on thyrocytes; 2) profound reductions of thyroid stimulating hormone (TSH) receptor antibodies (TSHR-Ab) and TPO antibodies (TPO-Ab); 3) prevention of dysregulation of cell-mediated immunity and B cell function; 4) neutralising reactive oxygen species (ROS) and inhibition of redox control processes required for the activation, differentiation and action of lymphocytes, macrophages, neutrophils, natural killer cells involved in both acute and chronic orbital inflammation in TAO; 5) inhibition of expression of pro-inflammatory cytokines and 6) inhibition of prostaglandin and leukotriene synthesis. An increased oxidative stress has been observed in both acute and chronic phases of thyroid disease with raised tissue concentrations of ROS. The benefits of Se supplementation in individuals with TAO appear to be proportionate to the degree of systemic activity of the thyroid disease. The maximal benefit of Se supplementation is therefore seen in the subjects who are hyperthyroid. Restoration of euthyroidism is one of the main goals in the management of TAO and when anti-thyroid drugs are combined with Se, the patients with Graves' disease (GD) and autoimmune thyroiditis (AIT) achieved euthyroidism faster than those treated with anti-thyroid drugs alone. Se status of normal adult humans can vary widely and Se supplementation may confer benefit only if serum Se levels are insufficient. The author recommends that serum Se levels of patients with TAO to be assessed prior to and during Se supplementation at regular intervals to avoid potential iatrogenic chronic Se overdose. PMID:24790886

  3. Selenium supplementation in thyroid associated ophthalmopathy: an update.

    PubMed

    Dharmasena, Aruna

    2014-01-01

    The therapeutic effect of selenium (Se) has already been proven in thyroid disease and thyroid associated ophthalmopathy (TAO). In spite of clear scientific proof of its benefits in TAO, there appears to be no clear agreement among the clinicians regarding its optimum dose, duration of the treatment, efficacy and safety to date. In this review, the author summarises the findings of 135 English language articles published on this subject over the past four decades from 1973 to 2013. The regulation and metabolism of thyroid hormones require a steady supply of Se and recent studies have revealed several possible mechanisms by which Se improves the severity of thyroid disease and TAO. These mechanisms include 1) inhibitory effect of HLA-DR molecule expression on thyrocytes; 2) profound reductions of thyroid stimulating hormone (TSH) receptor antibodies (TSHR-Ab) and TPO antibodies (TPO-Ab); 3) prevention of dysregulation of cell-mediated immunity and B cell function; 4) neutralising reactive oxygen species (ROS) and inhibition of redox control processes required for the activation, differentiation and action of lymphocytes, macrophages, neutrophils, natural killer cells involved in both acute and chronic orbital inflammation in TAO; 5) inhibition of expression of pro-inflammatory cytokines and 6) inhibition of prostaglandin and leukotriene synthesis. An increased oxidative stress has been observed in both acute and chronic phases of thyroid disease with raised tissue concentrations of ROS. The benefits of Se supplementation in individuals with TAO appear to be proportionate to the degree of systemic activity of the thyroid disease. The maximal benefit of Se supplementation is therefore seen in the subjects who are hyperthyroid. Restoration of euthyroidism is one of the main goals in the management of TAO and when anti-thyroid drugs are combined with Se, the patients with Graves' disease (GD) and autoimmune thyroiditis (AIT) achieved euthyroidism faster than those treated with anti-thyroid drugs alone. Se status of normal adult humans can vary widely and Se supplementation may confer benefit only if serum Se levels are insufficient. The author recommends that serum Se levels of patients with TAO to be assessed prior to and during Se supplementation at regular intervals to avoid potential iatrogenic chronic Se overdose. PMID:24790886

  4. Development of Thyroid-Associated Ophthalmopathy in Patients Who Underwent Total Thyroidectomy

    PubMed Central

    Jang, Sun Young; Lee, Ka Hyun; Oh, Jong Rok; Kim, Bo Yeon

    2015-01-01

    Purpose To report clinical characteristics of thyroid-associated ophthalmopathy (TAO) in patients who previously underwent total thyroidectomy for thyroid cancer or a benign mass of the thyroid. Materials and Methods Of the patients who were diagnosed with TAO from March 2008 to March 2012, we performed a retrospective chart review on those who had undergone total thyroidectomy for thyroid cancer or a benign mass of the thyroid before the occurrence of ophthalmopathy. Results Of the 206 patients diagnosed with TAO, seven (3.4%) met the inclusion criteria. The mean age of the subjects was 47.4 years, and all were female. Six patients were diagnosed with papillary thyroid cancer, and one was diagnosed with a benign mass. The duration between total thyroidectomy and onset of TAO ranged from 3-120 months (median 48 months). Ophthalmic manifestations varied among cases. Except for the patient who was diagnosed with a benign mass, all patients showed hyperthyroid status and were under Synthroid hormone treatment at the time of TAO development. Five of these six patients had positive levels of thyroid-stimulating hormone (TSH) receptor autoantibodies. Conclusion TAO rarely develops after total thyroidectomy, and the mechanism of TAO occurrence is unclear. However, most patients showed abnormalities in thyroid function and TSH receptor autoantibodies. PMID:26256985

  5. MiRNA-21 promotes fibrosis in orbital fibroblasts from thyroid-associated ophthalmopathy

    PubMed Central

    Bo-ding, Tong; Man-Yi, Xiao; Jie-Xi, Zeng

    2015-01-01

    Purpose This study aimed to determine the role of miR-21 in orbital fibroblasts obtained from donors with thyroid-associated ophthalmopathy (TAO) and to elucidate the regulation of fibrosis by miR-21 in the pathological process of TAO. Methods The expression of miR-21 was investigated in orbital tissues from 26 donors with TAO and 10 donors without TAO. Human orbital fibroblasts were cultivated from TAO donors, and the role of miR-21 in orbital fibroblast proliferation, apoptosis, and differentiation was analyzed. Moreover, the effect of transforming growth factor-beta1 (TGF-?1) on miR-21 expression was also analyzed. In addition, the regulation of miR-21 in TGF-?1-induced collagen production was determined. Results The expression of miR-21 in orbital fibroblasts from TAO was higher than in donors without TAO. Additional experiments demonstrated that miR-21 enhanced proliferation, decreased apoptosis, and promoted differentiation in TAO orbital fibroblasts. Moreover, this study also showed that TGF-?1 induced miR-21 expression in a time- and dose-dependent manner and miR-21 promoted collagen I mRNA expression and total collagen production induced by TGF-?1. Additionally, miR-21 activated the TGF-?1/Smad signaling pathway by enhancing Smad3 phosphorylation. Conclusions The present study shows that miR-21 regulates cell proliferation, apoptosis, and differentiation in orbital fibroblasts from TAO, and acts as a mediator in TGF-?1-induced collagen production. These data predict a close association between miR-21 and orbital muscle fibrosis, and provide a novel therapeutic target for TAO. PMID:25873777

  6. Patient Information in Graves' Disease and Thyroid-Associated Ophthalmopathy: Readability Assessment of Online Resources

    PubMed Central

    Denniston, Alastair K.; Boelaert, Kristien; Franklyn, Jayne A.; Durrani, Omar M.

    2014-01-01

    Background: The Internet is a vital source of information for patients hoping to learn more about their disease. Health literacy of the general population is known to be poor, with the U.S. Department of Health and Human Services (USDHHS) recommending that patient-oriented literature be written at a fourth- to sixth-grade reading level to optimize comprehensibility. In this study we assessed the readability of online literature specifically for Graves' disease (GD) and thyroid-associated ophthalmopathy (TAO). Methods: Readability of the content of the top 20 English-language GD patient-oriented online resources and top 30 of the equivalent TAO resources returned by Google search was analyzed. Web pages were identified using the Google search terms “Graves' disease” and “Thyroid-Associated Ophthalmopathy,” respectively. Extraneous text (e.g., hyperlinks, affiliations, disclaimers) was removed. Relevant text proceeded to readability analysis using four validated measures: Flesch Reading Ease Score, Flesch-Kincaid Grade Level, Simple Measure of Gobbledygook, and Gunning-Fog Index. Readability was compared with USDHHS standards. Results: Overall, median word count (with interquartile range [IQR] and range) was 990 (IQR 846, 195–3867), with a median of 18 words per sentence (IQR 4.0, 7.5–28). Median Flesch Reading Ease Score was 46 (IQR 13, 24–64), Flesch-Kincaid Grade Level 11 (IQR 3.0, 7.2–17), Simple Measure of Gobbledygook 13 (IQR 2.0, 9.6–17), and Gunning-Fog Index 13 (IQR 3.0, 9.2–19), each equivalent to a reading level of >11th grade and “difficult” on the USDHHS classification. None of the web pages evaluated had readability scores in accordance with published guidelines. There was no significant difference with the country of origin of each web page, website commercial status, or with pages predominantly focused on GD or TAO. Conclusions: Readability scores for online GD and TAO patient-focused materials are inferior to those recommended. Screening of this online material, as well as subsequent revision, is crucial to increase future patient knowledge, satisfaction, and compliance. PMID:24040878

  7. Risk Factors For Developing Thyroid-Associated Ophthalmopathy Among Individuals with Graves Disease

    PubMed Central

    Stein, Joshua D.; Childers, David; Gupta, Shivani; Talwar, Nidhi; Nan, Bin; Lee, Brian J.; Smith, Terry J.; Douglas, Raymond

    2015-01-01

    Context Thyroid associated ophthalmopathy (TAO) is a common and debilitating manifestation of Graves disease (GD). Presently little is known about factors that may increase the risk of developing TAO among patients with GD. Objective The purpose of this study is to identify risk factors associated with the development of TAO among individuals who are newly-diagnosed with GD. Design, Setting, Patients In this longitudinal cohort study, all beneficiaries age ? 18 years with newly-diagnosed GD who were continuously enrolled in a large nationwide U.S. managed care network and who had ?1 visit to an eye care provider from 2001–2009 were identified. International Classification of Diseases (ICD-9-CM) billing codes were used to identify those who developed manifestations of TAO. Multivariable Cox regression was used to determine the hazard of developing TAO among persons who were newly-diagnosed with GD, with adjustment for sociodemographic factors, systemic medical conditions, thyroid stimulating hormone levels, and medical and surgical interventions for management of hyperthyroidism. Main Outcome Measure Hazard ratios (HR) with 95% confidence intervals (95% CIs). Results Of 8,404 patients with GD who met the inclusion criteria, 740 (8.8%) developed TAO (mean follow-up, 374 days since initial GD diagnosis). After adjustment for potential confounders, surgical thyroidectomy, alone or in combination with medical therapy, was associated with a 74%-decreased hazard for TAO (adjusted HR, 0.26 [95% CI, 0.12–0.51]), compared with radioactive iodine therapy alone. Statin use (for ?60 days in the past year, vs. <60 days or nonuse) was associated with a 40%-decreased hazard (HR, 0.60 [CI, 0.37–0.93]). No significant association was found for use of non-statin cholesterol-lowering medications or COX-2 inhibitors and development of TAO. Conclusion and Relevance If prospective studies can confirm our finding that thyroidectomy and statin exposure are associated with substantially reduced hazards for TAO in patients with GD, deliberate preventive measures for this burdensome manifestation of GD may become a reality. PMID:25502604

  8. Identification of thyroglobulin in orbital tissues of patients with thyroid-associated ophthalmopathy.

    PubMed

    Marinò, M; Lisi, S; Pinchera, A; Mazzi, B; Latrofa, F; Sellari-Franceschini, S; McCluskey, R T; Chiovato, L

    2001-02-01

    Thyroid-associated ophthalmopathy (TAO) is thought to have an autoimmune pathogenesis because of its association with autoimmune thyroid disease, in particular with Graves' disease. Nevertheless, the nature of the autoimmune reaction is unclear, and a target orbital autoantigen has not been conclusively identified. A widely discussed hypothesis is that antigens constitutively shared by the thyroid and orbital tissues are targets of an autoimmune reaction. It has been also postulated that a thyroid-soluble antigen, namely thyroglobulin (Tg), is transported to orbital tissues through the lymphatics, where it accumulates and elicits autoimmune damages in susceptible individuals. Here we have investigated whether Tg is present in orbital tissues from patients with TAO. Retrobulbar tissue specimens were obtained from three patients with Graves' disease and TAO who underwent decompressive orbitotomy, and at autopsy from two patients with no thyroid or eye disease. All patients with TAO had been previously treated with radioiodine to control Graves' hyperthyroidism. Western blot analysis with a monoclonal anti-Tg antibody showed the presence of intact Tg, both in soluble and membrane-associated fractions of orbital tissue extracts from the patients with TAO, in amounts estimated to range from approximately 320 to approximately 900 pg/microg of tissue protein. In contrast, Tg was not detected in orbital tissue extracts from patients with no thyroid or eye disease. Tg was also demonstrated in orbital tissue extracts from two of three patients with TAO by enzyme-linked immunosorbent assay (ELISA), in amounts estimated to range from approximately 450 to approximately 1000 pg/microg of protein. In addition, Tg in orbital tissue extracts from patients with TAO was immunoprecipitated by a rabbit anti-Tg antibody, suggesting that it retained its native conformation. An anti-thyroxine (T4) antibody captured in solid-phase Tg from orbital tissue extracts, showing that it contained thyroid hormone residues and had therefore originated in the thyroid. Tg-anti-Tg immune complexes were not found in orbital tissues, suggesting that if an autoimmune reaction to Tg occurs in TAO, it is likely to be cell mediated. PMID:11288989

  9. Benzylideneacetophenone derivatives attenuate IFN-?-induced IP-10/CXCL10 production in orbital fibroblasts of patients with thyroid-associated ophthalmopathy through STAT-1 inhibition

    PubMed Central

    Lee, Sung-Hee; Lim, Seul Ye; Choi, Ji Ha; Jung, Jae-Chul; Oh, Seikwan; Kook, Koung Hoon; Choi, Youn-Hee

    2014-01-01

    The aim of the present study was to identify a new candidate anti-inflammatory compound for use in the active stage of thyroid-associated ophthalmopathy (TAO). Benzylideneacetophenone compound JC3 [(2E)-3-(4-hydroxy-3-methoxyphenyl)phenylpro-2-en-l-one] was synthesized based on a structural modification of yakuchinone B, a constituent of the seeds of Alpinia oxyphylla, which belongs to the ginger family (Zingiberaceae), has been widely used in folk medicine as an anti-inflammatory phytochemical. Orbital fibroblasts were primarily cultured from patients with TAO, and the potential of JC3 to suppress the interferon (IFN)-?-induced protein (IP)-10/CXCL10 production in these cells was determined. IFN-? strongly increased the level of IP-10/CXCL10 in orbital fibroblasts from patients with TAO. JC3 exerted a significant inhibitory effect on the IFN-?-induced increase in IP-10/CXCL10 in a dose-dependent manner; its potency was greater than that of an identical concentration of yakuchinone B with no toxicity to cells at the concentration range used. Moreover, the constructed dimer and trimer polystructures of JC3, showed greater potency than JC3 in suppressing the IFN-?-induced production of IP-10/CXCL10. JC3 significantly attenuated the IP-10/CXCL10 mRNA expression induced by IFN-?, and a gel-shift assay showed that JC3 suppressed IFN-?-induced DNA binding of signal transducer and activator of transcription-1 (STAT-1) in TAO orbital fibroblasts. Our results provide initial evidence that the JC3 compound reduces the levels of IP-10/CXCL10 protein and mRNA induced by IFN-? in orbital fibroblasts of TAO patients. Therefore, JC3 might be considered as a future candidate for therapeutic application in TAO that exerts its effects by modulating the pathogenic mechanisms in orbital fibroblasts. PMID:24924312

  10. Semiautomatic Regional Segmentation to Measure Orbital Fat Volumes in Thyroid-Associated Ophthalmopathy

    PubMed Central

    Comerci, M.; Elefante, A.; Strianese, D.; Senese, R.; Bonavolontà, P.; Alfano, B.; Bonavolontà, G.; Brunetti, A.

    2013-01-01

    Summary This study was designed to validate a novel semi-automated segmentation method to measure regional intra-orbital fat tissue volume in Graves' ophthalmopathy. Twenty-four orbits from 12 patients with Graves' ophthalmopathy, 24 orbits from 12 controls, ten orbits from five MRI study simulations and two orbits from a digital model were used. Following manual region of interest definition of the orbital volumes performed by two operators with different levels of expertise, an automated procedure calculated intra-orbital fat tissue volumes (global and regional, with automated definition of four quadrants). In patients with Graves' disease, clinical activity score and degree of exophthalmos were measured and correlated with intra-orbital fat volumes. Operator performance was evaluated and statistical analysis of the measurements was performed. Accurate intra-orbital fat volume measurements were obtained with coefficients of variation below 5%. The mean operator difference in total fat volume measurements was 0.56%. Patients had significantly higher intra-orbital fat volumes than controls (p<0.001 using Student's t test). Fat volumes and clinical score were significantly correlated (p<0.001). The semi-automated method described here can provide accurate, reproducible intra-orbital fat measurements with low inter-operator variation and good correlation with clinical data. PMID:24007725

  11. Semiautomatic regional segmentation to measure orbital fat volumes in thyroid-associated ophthalmopathy. A validation study.

    PubMed

    Comerci, M; Elefante, A; Strianese, D; Senese, R; Bonavolontà, P; Alfano, B; Bonavolontà, B; Brunetti, A

    2013-08-01

    This study was designed to validate a novel semi-automated segmentation method to measure regional intra-orbital fat tissue volume in Graves' ophthalmopathy. Twenty-four orbits from 12 patients with Graves' ophthalmopathy, 24 orbits from 12 controls, ten orbits from five MRI study simulations and two orbits from a digital model were used. Following manual region of interest definition of the orbital volumes performed by two operators with different levels of expertise, an automated procedure calculated intra-orbital fat tissue volumes (global and regional, with automated definition of four quadrants). In patients with Graves' disease, clinical activity score and degree of exophthalmos were measured and correlated with intra-orbital fat volumes. Operator performance was evaluated and statistical analysis of the measurements was performed. Accurate intra-orbital fat volume measurements were obtained with coefficients of variation below 5%. The mean operator difference in total fat volume measurements was 0.56%. Patients had significantly higher intra-orbital fat volumes than controls (p<0.001 using Student's t test). Fat volumes and clinical score were significantly correlated (p<0.001). The semi-automated method described here can provide accurate, reproducible intra-orbital fat measurements with low inter-operator variation and good correlation with clinical data. PMID:24007725

  12. Thiazolidinedione induced thyroid associated orbitopathy

    PubMed Central

    Lee, Seongmu; Tsirbas, Angelo; Goldberg, Robert A; McCann, John D

    2007-01-01

    Background To describe an episode of thyroid associated orbitopathy (TAO) following the initiation of thiazolidinedione (TZD). Case presentation We report a female patient with a history of Graves' disease and stabilised thyroid associated orbitopathy for 2.5 years, who experienced rapid progression of TAO after the initiation of thiazolidinedione for glycemic control. Following the discontinuation of TZD, the patient experienced subsequent stabilisation of disease and normalization of vision. The medical history, ophthalmic findings, and clinical course are discussed. Conclusion Thiazolidinediones may exacerbate TAO, and this should be taken into consideration when selecting treatment for diabetic patients with a history of autoimmune thyroid disorders. PMID:17462097

  13. Thyroid-associated orbitopathy is linked to gastrointestinal autoimmunity

    PubMed Central

    Ponto, K A; Schuppan, D; Zwiener, I; Binder, H; Mirshahi, A; Diana, T; Pitz, S; Pfeiffer, N; Kahaly, G J

    2014-01-01

    Common autoimmune disorders tend to co-exist in the same subjects and cluster in families. The objective of this study was to determine the prevalence of autoimmune co-morbidity in patients with autoimmune thyroid disease (AITD) with and without thyroid-associated orbitopathy (TAO). This was a cross-sectional study conducted at an academic tertiary referral centre. Of 1310 patients with AITD [n?=?777 or 59% with Graves' disease (GD) and n?=?533, 41% with Hashimoto's thyroiditis (HT)] followed at a specialized joint thyroid–eye out-patient clinic, 176 (13·4%) had an adult type of the autoimmune polyglandular syndrome, 129 (9·8%) type 1 diabetes, 111 (8·5%) coeliac disease, 60 (4·6%) type A autoimmune gastritis, 57 (4·4%) vitiligo and 25 (1·9%) Addison's disease. Coeliac disease and autoimmune gastritis were associated positively with GD [odds ratio (OR)?=?2·18; P?=?0·002 and OR?=?6·52; P?TAO, 584 (95·7%) and 26 (4·3%) had GD and HT, respectively (P?TAO was most prevalent in GD patients with coeliac disease (94%, OR?=?1·87, P?TAO while type 1 diabetes, Addison's disease and alopecia areata were protective for TAO. In patients with TAO, coeliac disease is the most prevalent co-morbid autoimmune condition and rates are increased compared to GD patients without TAO. PMID:24903731

  14. Significance of serum antibodies reactive with flavoprotein subunit of succinate dehydrogenase in thyroid associated orbitopathy

    PubMed Central

    Hosal, B.; Swanson, J.; Thompson, C.; Kubota, S.; Gunji, K.; Kennerdell, J.; Wall, J.

    1999-01-01

    AIMS—Thyroid associated orbitopathy (TAO) is an autoimmune disorder of extraocular muscles and orbital connective tissue. Identification of the principal target antigens would help the understanding of the pathogenesis of the disease and possibly lead to the development of specific therapies in the future. The purpose of this study was to measure serum antibodies against the flavoprotein subunit of succinate dehydrogenase in patients with TAO and correlate their presence with factors of TAO.?METHODS—Sera of patients with active TAO of 6 months' duration or less were tested for antibodies against the flavoprotein subunit of succinate dehydrogenase. Clinical data were obtained by retrospective review of patients' charts. Enzyme linked immunosorbent assay was used to test sera for serum antibodies against purified succinate dehydrogenase.?RESULTS—38 patients with TAO and 32 healthy age and sex matched controls were included in the study. Anti-flavoprotein antibodies were detected in 24 out of 38 patients with TAO (63.16%) and in five out of 32 healthy controls (15.63%) (p<0.01). Neither age, sex, duration of thyroid disease, thyroid status, treatment of thyroid disease, smoking history, duration of orbitopathy, activity of orbitopathy, nor the presence of lid retraction were significantly associated with the presence of serum anti-flavoprotein antibodies (p>0.05). However, the total number of rectus muscles affected in both eyes of the patients was significantly correlated with the finding of a positive antibody test (p<0.05).?CONCLUSIONS—Serum antibodies reactive with the flavoprotein subunit of succinate dehydrogenase are associated with extraocular muscle involvement in active TAO of recent onset.?? PMID:10216063

  15. TAO users manual.

    SciTech Connect

    Benson, S.; McInnes, L. C.; More, J. J.; Sarich, J.

    2003-12-02

    The Toolkit for Advanced Optimization (TAO) focuses on the design and implementation of component-based optimization software for the solution of large-scale optimization applications on high-performance architectures. Their approach is motivated by the scattered support for parallel computations and lack of reuse of linear algebra software in currently available optimization software. The TAO design allows the reuse of toolkits that provide lower-level support (parallel sparse matrix data structures, preconditioners, solvers), and thus they are able to build on top of these toolkits instead of having to redevelop code. The advantages in terms of efficiency and development time are significant. The TAO design philosophy uses object-oriented techniques of data and state encapsulation, abstract classes, and limited inheritance to create a flexible optimization toolkit. This chapter provides a short introduction to the design philosophy by describing the objectives in TAO and the importance of this design. Since a major concern in the TAO project is the performance and scalability of optimization algorithms on large problems, they also present some performance results.

  16. Graves' ophthalmopathy evaluated by infrared eye-movement recordings

    SciTech Connect

    Feldon, S.E.; Unsoeld, R.

    1982-02-01

    Thirteen patients with varying degrees of Graves' ophthalmopathy were examined using high-resolution infrared oculography to determine peak velocities for horizontal eye movements between 3 degrees and 30 degrees. As severity of the orbital disease increased, peak velocities became substantially lower. Vertical-muscle surgery failed to have any effect on peak velocity of horizontal eye movements. In contrast, orbital decompression caused notable improvement in peak velocity of eye movements. Eye-movement recordings, which provide a measure of extraocular muscle function rather than structure, may provide a safe, sensitive, and accurate method for classifying and following up patients with Graves' ophthalmopathy.

  17. The relationship between Graves’ ophthalmopathy and dry eye syndrome

    PubMed Central

    Selter, Jessica H; Gire, Anisa I; Sikder, Shameema

    2015-01-01

    Background A complex relationship between Graves’ ophthalmopathy (GO) and dry eye syndrome exists. New research brings more insight into the association between these two diseases. Methods A review of the literature was conducted using the query terms “Graves’ Ophthalmopathy”, “Thyroid Eye Disease”, and “Dry Eye” in MedLine (PubMed) and Scopus. A total of 55 papers were reviewed. Case reports were excluded. Conclusion This review paper shows the close relationship between dry eye syndrome and GO. The underlying mechanisms behind their association suggest mechanical impairment of orbital muscles and immune-mediated lacrimal gland dysfunction as the causes of dry eye in GO patients. However, there are a variety of treatment options available for patients with GO with signs of dry eye, which help combat this issue. PMID:25584018

  18. American Thyroid Association Guide to Investigating Thyroid Hormone Economy and Action in Rodent and Cell Models

    PubMed Central

    Anderson, Grant; Forrest, Douglas; Galton, Valerie Anne; Gereben, Balázs; Kim, Brian W.; Kopp, Peter A.; Liao, Xiao Hui; Obregon, Maria Jesus; Peeters, Robin P.; Refetoff, Samuel; Sharlin, David S.; Simonides, Warner S.; Weiss, Roy E.; Williams, Graham R.

    2014-01-01

    Background: An in-depth understanding of the fundamental principles that regulate thyroid hormone homeostasis is critical for the development of new diagnostic and treatment approaches for patients with thyroid disease. Summary: Important clinical practices in use today for the treatment of patients with hypothyroidism, hyperthyroidism, or thyroid cancer are the result of laboratory discoveries made by scientists investigating the most basic aspects of thyroid structure and molecular biology. In this document, a panel of experts commissioned by the American Thyroid Association makes a series of recommendations related to the study of thyroid hormone economy and action. These recommendations are intended to promote standardization of study design, which should in turn increase the comparability and reproducibility of experimental findings. Conclusions: It is expected that adherence to these recommendations by investigators in the field will facilitate progress towards a better understanding of the thyroid gland and thyroid hormone dependent processes. PMID:24001133

  19. Subclassification of Follicular Neoplasms Recommended by the Japan Thyroid Association Reporting System of Thyroid Cytology

    PubMed Central

    Kakudo, Kennichi; Kameyama, Kaori; Hirokawa, Mitsuyoshi; Katoh, Ryohei; Nakamura, Hirotoshi

    2015-01-01

    Background. The Japan Thyroid Association recently published guidelines for clinical practice for the management of thyroid nodules, which include a diagnostic system for reporting thyroid fine needle aspiration cytology. It is characterized by the subclassification of follicular neoplasms, which is different from other internationally accepted reporting systems. Materials and Methods. This study examined observer variability in the subclassification of follicular neoplasms among 4 reviewers using Papanicolaou-stained smear samples from 20 surgically treated patients with indeterminate cytology. Results. The favor malignant subcategory had high predictive value of malignancy (risk of malignancy: 60–75%) and good agreement among the 4 reviewers (? = 0.7714). Conclusion. These results clearly confirmed that the risk stratification of follicular neoplasms, which was adapted from cytology practice of high-volume thyroid centers in Japan, can provide clinically helpful information to estimate the risk of malignancy and to triage patients for surgery. PMID:25722720

  20. Graves' Ophthalmopathy: VISA versus EUGOGO Classification, Assessment, and Management

    PubMed Central

    Barrio-Barrio, Jesús; Sabater, Alfonso L.; Bonet-Farriol, Elvira; Velázquez-Villoria, Álvaro; Galofré, Juan C.

    2015-01-01

    Graves' ophthalmopathy (GO) is an autoimmune inflammatory disorder associated with thyroid disease which affects ocular and orbital tissues. GO follows a biphasic course in which an initial active phase of progression is followed by a subsequent partial regression and a static inactive phase. Although the majority of GO patients have a mild, self-limiting, and nonprogressive ocular involvement, about 3–7% of GO patients exhibit a severe sight-threatening form of the disease due to corneal exposure or compressive optic neuropathy. An appropriate assessment of both severity and activity of the disease warrants an adequate treatment. The VISA (vision, inflammation, strabismus, and appearance), and the European Group of Graves' Orbitopathy (EUGOGO) classifications are the two widely used grading systems conceived to assess the activity and severity of GO and guide the therapeutic decision making. A critical analysis of classification, assessment, and management systems is reported. A simplified “GO activity assessment checklist” for routine clinical practice is proposed. Current treatments are reviewed and management guidelines according to the severity and activity of the disease are provided. New treatment modalities such as specific monoclonal antibodies, TSH-R antagonists, and other immunomodulatory agents show a promising outcome for GO patients. PMID:26351570

  1. Does autoimmunity against thyroglobulin play a role in the pathogenesis of Graves’ ophthalmopathy: a review

    PubMed Central

    Shanmuganathan, Thayalini; Girgis, Christian; Lahooti, Hooshang; Champion, Bernard; Wall, Jack R

    2015-01-01

    While most authors believe that autoimmunity against the TSH receptor expressed in the orbital connective tissue cells is the main reaction that leads to the development of ophthalmopathy in patients with Graves’ hyperthyroidism, an older hypothesis that deserves fresh consideration is based on the notion that thyroglobulin (Tg) in the thyroid gland passes in a retrograde fashion to the orbit where it is recognized by Tg autoantibodies, leading to inflammation. Here, we review new evidence that supports a role of Tg and propose a new hypothesis based on the notion that Tg is targeted in the orbit leading to a complex cascade of reactions that leads to Graves’ ophthalmopathy. PMID:26664042

  2. Current Insights into the Pathogenesis of Graves' Ophthalmopathy.

    PubMed

    Bahn, R S

    2015-09-01

    Environmental, genetic, and immune factors are at play in the development of the variable clinical manifestations of Graves' ophthalmopathy (GO). Among the environmental contributions, smoking is the risk factor most consistently linked to the development or worsening of the disease. The close temporal relationship between the diagnoses of Graves' hyperthyroidism and GO have long suggested that these 2 autoimmune conditions may share pathophysiologic features. The finding that the thyrotropin receptor (TSHR) is expressed in orbital fibroblasts, the target cells in GO, supported the notion of a common autoantigen. Both cellular and humeral immunity directed against TSHR expressed on orbital fibroblasts likely initiate the disease process. Activation of helper T cells recognizing TSHR peptides and ligation of TSHR by TRAb lead to the secretion of inflammatory cytokines and chemokines, and enhanced hyaluronic acid (HA) production and adipogenesis. The resulting connective tissue remodeling results in varying degrees extraocular muscle enlargement and orbital fat expansion. A subset of orbital fibroblasts express CD34, are bone-marrow derived, and circulate as fibrocytes that infiltrate connective tissues at sites of injury or inflammation. As these express high levels of TSHR and are capable of producing copious cytokines and chemokines, they may represent an orbital fibroblast population that plays a central role in GO development. In addition to TSHR, orbital fibroblasts from patients with GO express high levels of IGF-1R. Recent studies suggest that these receptors engage in cross-talk induced by TSHR ligation to synergistically enhance TSHR signaling, HA production, and the secretion of inflammatory mediators. PMID:26361262

  3. Common Immunosuppressive Monotherapy for Graves’ Ophthalmopathy: A Meta-Analysis

    PubMed Central

    Li, Yu-Zhen; Lou, Heng; Zeng, Cheng-Cheng; Wang, Qiu-Hong; Cheng, Jin-Wei; Wei, Rui-Li

    2015-01-01

    Background Several immunosuppressive therapeutic regimens are widely used to treat Graves’ ophthalmopathy (GO), including oral glucocorticoids (OGC), intravenous glucocorticoids (IVGC), retrobulbar injections of glucocorticoids (ROGC) and orbital radiotherapy (OR). The priority among these is unknown. This meta-analysis investigated the efficacy and tolerability of the above regimens. Methods The PubMed, EMBASE, and Cochrane Library databases and the Chinese Biomedicine Database were searched up to November 18, 2014. Randomized controlled trials (RCTs) comparing monotherapies (OGC, IVGC, ROGC and OR) in patients with moderate-to-severe active GO were selected. The main efficacy measures were the response rate, the standard mean difference (SMD) in the reduction in the clinical activity score (CAS) and the mean difference (MD) in proptosis from baseline to the end of treatment. The main tolerability measure was the risk ratio (RR) for adverse events. The pooled estimates and 95% confidence intervals (95% CIs) were calculated using the RevMan software, version 5.1. Results Seven published RCTs involving 328 participants were included in the present meta-analysis, including IVGC versus OGC (3 trials), ROGC versus OGC (3 trials) and OR versus OGC (1 trial). IVGC was more effective than OGC in response rate (RR = 1.48, 95% CI = 1.18–1.87) and had an obvious CAS reduction (SMD = 0.69, 95% CI = 0.13–1.25). IVGC caused fewer adverse events than OGC. ROGC and OGC had no statistically significant difference in response rate (RR = 1.16, 95% CI = 0.94–1.42). OR also did not differ significantly compared with OGC (RR = 0.93, 95% CI = 0.54–1.60). ROGC and OR had fewer adverse events, such as weight gain, compared with OGC. Conclusions For patients with GO in the moderate-to-severe active phase, current evidence gave priority to IVGC, which had a statistically significant advantage over OGC and caused fewer adverse events. ROGC and OR did not provide greater efficacy than OGC, although better tolerability and fewer adverse events were shown. PMID:26469187

  4. Cervical Lymph Nodes, Thyroiditis and Ophthalmopathy: The Pleomorphic Face of an Immunoglobulin G4-Related Disease

    PubMed Central

    Ghys, Christophe; Depierreux, Michel; Ozalp, Elçin; Velkeniers, Brigitte

    2014-01-01

    We report a case of immunoglobulin G4-related disease (IgG4-RD) presenting with a clinical course suggestive of fibrosing thyroiditis and endocrine ophthalmopathy associated with enlarged cervical lymph nodes. This clinical presentation should prompt a search for associated systemic disorders, including an IgG4-RD. The clue to the exact diagnosis of the underlying disease is histological examination showing an IgG4 plasmatocytic infiltrate in the inflammatory organs involved. PMID:25759802

  5. Retrobulbar T cells from patients with Graves' ophthalmopathy are CD8+ and specifically recognize autologous fibroblasts.

    PubMed Central

    Grubeck-Loebenstein, B; Trieb, K; Sztankay, A; Holter, W; Anderl, H; Wick, G

    1994-01-01

    Graves' ophthalmopathy is an autoimmune condition characterized by T cell infiltration of the retrobulbar tissue. Phenotypic and functional analysis of these infiltrating cells may provide insight into the pathogenesis of the disease. IL-2-responsive cells were therefore grown out of the retrobulbar tissue from two patients with severe Graves' ophthalmopathy undergoing orbital decompression surgery, and six T cell lines were established and characterized. They consisted predominantly of CD8 + CD45RO+ cells and secreted IL-4, IFN-gamma, and IL-10 upon activation. When screened for their antigen reactivity, all lines proliferated in response to stimulation with autologous retrobulbar fibroblasts in an HLA class I-restricted manner, but did not recognize autologous peripheral blood mononuclear cells, crude eye muscle extract, allogeneic cells, or purified protein derivate of Mycobacterium tuberculosis. In contrast, PBMC from the same patients responded readily to purified protein derivate of Mycobacterium tuberculosis and allogeneic PBMC, but did not recognize autologous fibroblasts. Interestingly, only one of the six retrobulbar T cell lines displayed cytotoxicity towards its specific target cell population. These results suggest that the retrobulbar fibroblasts are a major T cell target in Graves' ophthalmopathy. Pronounced cytokine production in the absence of target cell cytotoxicity may explain fibroblast proliferation, glycosaminoglycan secretion, and secondary eye muscle enlargement in this condition. Images PMID:8201012

  6. TAOS/LS1 development final report

    SciTech Connect

    Phipps, G.S.; Gentry, S.M.; Falls, J.M.; Claassen, P.J.; Alder, G.J.

    1997-12-01

    The Laser Sensor No. 1 (LS1) is a system designed and built by Sandia to detect and report laser illumination of an orbiting satellite. It was launched March 1994 as part of the U.S. Air Force Phillips Laboratory, Technology for Autonomous Operational Survivability (TAOS) satellite program. The engineering details of the system are described in this report. Operation characteristics and results have been reserved for inclusion in a classified Air Force report prepared by the TAOS Program Office of Phillips Laboratory.

  7. Ocular Changes and Approaches of Ophthalmopathy in Basedow – Graves- Parry- Flajani Disease

    PubMed Central

    SARACI, George; TRETA, Anamaria

    2011-01-01

    ABSTRACT Basedow-Graves disease is an autoimmune condition with multiple local and systemic aspects. Among these, oculopathy has a major impact on patient's life from both functional and esthetic point of view. Basedow-Graves oculopathy requires an appropriate positive and differential diagnosis using clinical and imagistic approaches. Treatment is always required in moderate or severe forms and it begins with simple general points and continues with medical and surgical therapies. Current article stresses upon the most characteristic clinical signs of thyroidian ophthalmopathy and the required current therapeutic approaches. PMID:22205899

  8. Immunotherapy in miscellaneous medical disorders Graves ophthalmopathy, asthma, and regional painful syndrome.

    PubMed

    Gonzales, Michael; Fratianni, Carmel; Mamillapali, Chaitanya; Khardori, Romesh

    2012-05-01

    In Graves ophthalmopathy, immunotherapy is offering an opportunity of reducing bad outcomes that lead to disfigurement and impairment of vision. These therapies are not perfect; however, we now have a chance to achieve better outcomes. In asthma, immune therapy using passive immunity targeting key proinflammatory cytokine/chemokines and medications of their effects has opened an avenue of research into a safe and durable therapy. Omalizumab appears to be safe and effective in clinical use. In regional pain syndrome, immune mechanisms may be involved in sustaining long-standing pain, and IVIG may moderate pain sensitivity by reducing immune activation. PMID:22703859

  9. Protracted Hypofractionated Radiotherapy for Graves' Ophthalmopathy: A Pilot Study of Clinical and Radiologic Response

    SciTech Connect

    Casimiro de Deus Cardoso, Cejana; Giordani, Adelmo Jose; Borri Wolosker, Angela Maria; Souhami, Luis; Gois Manso, Paulo; Souza Dias, Rodrigo; Comodo Segreto, Helena Regina; Araujo Segreto, Roberto

    2012-03-01

    Purpose: To evaluate the clinical and radiologic response of patients with Graves' ophthalmopathy given low-dose orbital radiotherapy (RT) with a protracted fractionation. Methods and Materials: Eighteen patients (36 orbits) received orbital RT with a total dose of 10 Gy, fractionated in 1 Gy once a week over 10 weeks. Of these, 9 patients received steroid therapy as well. Patients were evaluated clinically and radiologically at 6 months after treatment. Clinical response assessment was carried out using three criteria: by physical examination, by a modified clinical activity score, and by a verbal questionnaire considering the 10 most common signs and symptoms of the disease. Radiologic response was assessed by magnetic resonance imaging. Results: Improvement in ocular pain, palpebral edema, visual acuity, and ocular motility was observed in all patients. Significant decrease in symptoms such as tearing (p < 0.001) diplopia (p = 0.008), conjunctival hyperemia (p = 0.002), and ocular grittiness (p = 0.031) also occurred. Magnetic resonance imaging showed decrease in ocular muscle thickness and in the intensity of the T2 sequence signal in the majority of patients. Treatments were well tolerated, and to date no complications from treatment have been observed. There was no statistical difference in clinical and radiologic response between patients receiving RT alone and those receiving RT plus steroid therapy. Conclusion: RT delivered in at a low dose and in a protracted scheme should be considered as a useful therapeutic option for patients with Graves' ophthalmopathy.

  10. 77 FR 59703 - Environmental Impact Statement; Taos Regional Airport, Taos, NM

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-28

    ...the ``Taos Regional Airport, Airport Layout Plan Improvements'' Environmental Impact...FAA to approve revisions to its Airport Layout Plan (ALP) to reflect and allow construction...FAA to approve revisions to its Airport Layout Plan (ALP) and provide funding for...

  11. Pai-Chun Tao REYST report 06-2011

    E-print Network

    Karlsson, Brynjar

    -ion battery manufacturing using geothermal energy in Iceland REYKJAVÍK ENERGY GRADUATE SCHOOL OF SUSTAINABLE manufacturing using geothermal energy in Iceland by Pai-Chun Tao Thesis MSc of Sustainable Energy manufacturing using geothermal energy in Iceland Pai-Chun Tao Thesis submitted to the School of Science

  12. TAOS. Trajectory Analysis and Optimization System

    SciTech Connect

    Salguero, D.E.

    1995-12-09

    TAOS is a general-purpose software tool capable of analyzing nearly any type of three degree-of-freedom point-mass, high-speed trajectory. Input files contain aerodynamic coefficients, propulsion data, and a trajectory description. The trajectory description divides the trajectory into segments, and within each segment, guidance rules provided by the user describe how the trajectory is computed. Output files contain tabulated trajectory information such as position, velocity, and acceleration. Parametric optimization provides a powerful method for satisfying mission-planning constraints, and trajectories involving more than one vehicle can be computed within a single problem.

  13. Prevalence of Graves’ ophthalmopathy in patients with Graves’ disease presenting to a referral centre in north India

    PubMed Central

    Reddy, Sagili Vijaya Bhaskar; Jain, Anu; Yadav, Subhash B.; Sharma, Kumudini; Bhatia, Eesh

    2014-01-01

    Background & objectives: The prevalence of Graves’ ophthalmopathy (GO) varies widely in different ethnic groups. Indians have been reported to have a lower prevalence of Graves’ ophthalmopathy as compared to Caucasians of European origin, but data are sparse and inconclusive. We studied the prevalence, clinical features and association of GO in Indian patients with Graves’ disease attending a referral centre in north India. Methods: A prospective study was conducted on 235 consecutive newly referred north Indian patients with Graves’ disease presenting to a tertiary care centre in north India. All patients underwent a comprehensive ophthalmological examination as per the European Group on Graves’ Orbitopathy (EUGOGO) recommendations. Results: GO was diagnosed in 65 patients (prevalence 28%; 95% confidence interval 22-33%). The prevalence was similar in males (28%) and females (27%). It was mild in 83 per cent, moderate-severe in 15 per cent and sight-threatening in only 2 per cent of cases. Ophthalmopathy was clinically active in only two (3%) cases. Upper eyelid retraction was the most common manifestation (83%), followed by exophthalmos (75%). Extra-ocular muscle involvement (5%) and optic nerve dysfunction (2%) were uncommon. The risk of GO was 3.9- fold (95% confidence interval 1.1-13.6) higher in smokers compared to non-smokers. However, severity of disease in smokers was similar to non-smokers. On multivariate logistic regression analysis, GO was associated only with high thyrotropin receptor antibody titres and current smoking. Interpretation & conclusions: Among north Indian patients with GD studied at a referral center, the prevalence of GO was similar to Caucasians of European descent, but clinically active and severe ophthalmopathy was uncommon. More studies are needed to confirm these findings. PMID:24604044

  14. Taos Pueblo Students Hunt Leprechauns in Science and Language Arts.

    ERIC Educational Resources Information Center

    Miller, Nola; Smith, Walter S.

    1999-01-01

    Describes an elementary school project--a "leprechaun trap"--that included elements of technology, science, language arts, and problem solving. Discusses how technology education is helping the Taos Pueblo community build bridges between its past and modern technologies. (JOW)

  15. TRUTH AND ACTION OSMOSIS (THE TAO COMPUTATION MODEL)

    E-print Network

    Vasconcelos, Vasco Thudichum

    TRUTH AND ACTION OSMOSIS (THE TAO COMPUTATION MODEL) ANT â?? ONIO PORTO, VASCO T. VASCONCELOS by the database. Commands always execute and as an e#ect may change the database. We thus have the osmosis

  16. Trajectory analysis and optimization system (TAOS) user`s manual

    SciTech Connect

    Salguero, D.E.

    1995-12-01

    The Trajectory Analysis and Optimization System (TAOS) is software that simulates point--mass trajectories for multiple vehicles. It expands upon the capabilities of the Trajectory Simulation and Analysis program (TAP) developed previously at Sandia National Laboratories. TAOS is designed to be a comprehensive analysis tool capable of analyzing nearly any type of three degree-of-freedom, point-mass trajectory. Trajectories are broken into segments, and within each segment, guidance rules provided by the user control how the trajectory is computed. Parametric optimization provides a powerful method for satisfying mission-planning constraints. Althrough TAOS is not interactive, its input and output files have been designed for ease of use. When compared to TAP, the capability to analyze trajectories for more than one vehicle is the primary enhancement, although numerous other small improvements have been made. This report documents the methods used in TAOS as well as the input and output file formats.

  17. American Thyroid Association

    MedlinePLUS

    ... Partner Relations Login Join Home About the ATA Leadership & Staff Governance Society Awards Society Committees Clark T. ... the ATA Give Online Home About the ATA Leadership & Staff Governance Society Awards Society Committees Clark T. ...

  18. A high iodine intake in Wistar rats results in the development of a thyroid-associated ectopic thymic tissue and is accompanied by a low thyroid autoimmune reactivity.

    PubMed Central

    Mooij, P; de Wit, H J; Drexhage, H A

    1994-01-01

    Evidence is accumulating that dietary iodine intake is an important modulator of autoimmune thyroid reactions. To study this role of iodine intake further, female Wistar rats were kept on an enriched iodine diet (EID, iodine intake 100 micrograms iodine/day) for a period of up to 18 weeks. Control rats were either on a normal iodine diet (NID, iodine intake 7 micrograms iodine/day) or a low iodine diet (LID, 2 days of 1% KClO4 followed by iodine-deficient drinking water/pellets). During the first 6 weeks of the EID rats developed a thyroid-associated ectopic thymic tissue (50-57% of the animals on EID versus 7-14% of NID rats and 0% of LID rats). This thyroid-associated ectopic thymic tissue showed a similar histology (cortex and medulla) and a similar marker pattern as normal rat thymus concerning TdT expression (positive cells in the cortex) and CD4/CD8 positivity (double-positive cells in the cortex, single-positive cells in the medulla). The excessive iodine diet also resulted in a lowered thyroid autoimmune reactivity as compared to the NID and LID, viz. (1) in a lower incidence of anti-colloid antibodies in serum (12.5% positivity in EID rats versus 36% in NID and 60% in LID rats at 18 weeks) and (2) lower numbers of intrathyroidal lymphoid cells, viz. lower numbers of dendritic cells and lower numbers of CD4 and CD8 positive lymphocytes. It is hypothesized that the development of the thyroid-associated ectopic thymic tissue in the EID rats is related to their low thyroid autoimmune responsiveness; the tissue might play a role in tolerance induction to thyroidal autoantigens. Images Figure 1 Figure 2 PMID:8157280

  19. Status of the Transneptunian Automated Occultation Survey (TAOS II)

    NASA Astrophysics Data System (ADS)

    Lehner, Matthew J.; Wang, Shiang Yu; Reyes-Ruiz, Mauricio; Chu, You Hua; Lee, William; Zhang, Zhi Wei; Cook, Kem H.; Norton, Timothy; Szentgyorgyi, Andrew; Alcock, Charles

    2015-11-01

    The Transneptunian Automated Occultation Survey (TAOS II) will aim to detect occultations of stars by small (~1 km diameter) objects in the Kuiper Belt and beyond. Such events are very rare (<10-3 events per star per year) and short in duration (~200 ms), so many stars must be monitored at a high readout cadence. TAOS II will operate three 1.3 meter telescopes at the Observatorio Astronómico Nacional at San Pedro Mártir in Baja California, México. With a 2.3 square degree field of view and a high speed camera comprising CMOS imagers, the survey will monitor 10,000 stars simultaneously with all three telescopes at a nominal readout cadence of 20 Hz. Construction of the site began in the fall of 2013. We present here an update on the status of the TAOS II survey, including the site development, camera fabrication, and project schedule.

  20. Current perspectives on the role of orbital fibroblasts in the pathogenesis of Graves' ophthalmopathy.

    PubMed

    Dik, Willem A; Virakul, Sita; van Steensel, Leendert

    2016-01-01

    Graves' ophthalmopathy (GO) is an extra-thyroidal complication of Graves' disease (GD; Graves' hyperthyroidism) characterized by orbital tissue inflammation, expansion, remodeling and fibrosis. Although the initiating trigger of GO is still indistinct, excessive orbital fibroblast activity is at the heart of its pathogenesis. Orbital fibroblasts are activated by cellular interactions with immune cells and the soluble factors they secrete. Orbital fibroblasts, especially from GO patients, express the thyrotropin receptor (TSH-receptor; TSHR), and activation of the orbital fibroblast population by stimulatory autoantibodies directed against the TSHR may provide an important link between GD and GO. Furthermore, stimulatory autoantibodies directed against the insulin-like growth factor-1 receptor have been proposed to contribute to orbital fibroblast activation in GO. Activated orbital fibroblasts produce inflammatory mediators thereby contributing to the orbital inflammatory process in GO. Moreover, orbital fibroblasts exhibit robust proliferative activity and extracellular matrix (especially hyaluronan) synthesizing capacity and can differentiate into adipocytes and myofibroblasts with disease progression, thereby contributing to tissue expansion/remodeling and fibrosis in GO. Orbital fibroblasts, especially those from GO patients, exhibit a hyper-responsive phenotype when compared to fibroblasts from other anatomical regions, which may further contribute to GO pathogenesis. Fibrocytes have been identified as additional source of orbital fibroblasts in GO, where they may contribute to orbital tissue inflammation, adipogenesis and remodeling/fibrosis. This review addresses our current view on the role that orbital fibroblasts fulfill in GO pathogenesis and both established as well as less established not fully crystallized concepts that need future studies will be discussed. PMID:26675405

  1. Genetic associations of FCRL3 polymorphisms with the susceptibility of Graves ophthalmopathy in a Chinese population

    PubMed Central

    Wu, Shanshan; Cai, Ting; Chen, Feng; He, Xuefei; Cui, Zhihua

    2015-01-01

    Background: Graves ophthalmopathy (GO) is a form of autoimmune thyroid disease commonly found in approximately 25-50% patients with Graves’ disease. Both the thyroid-specific genes and immune-modulating genes are involved in susceptibility to GO. However, even though FCRL3 polymorphisms were also autoimmune-associated genes, no study has been performed regarding the association of FCRL3 with GO. Therefore, the objective of the current study was to conduct a basic case-control study in a Chinese population. Methods and materials: Seven SNPs were selected in this case-control study and 577 GD patients and 608 controls were recruited. Odds ratio and 95% confidence interval were used to assess the association between susceptibility of GO and FCRL3 polymorphisms with Stata software (Version 11.0, Stata Corp LP, USA). Results: The case-control analysis showed that three polymorphisms, FCRL3_3C, FCRL3_5C, FCRL3_6A, were significantly associated with raised risk of GO in a Chinese Han population in the allelic model [OR = 1.28, 95% CI: 1.09-1.51, P = 0.003; OR = 1.26, 95% CI: 1.07-1.48, P = 0.005; OR = 1.25, 95% CI: 1.06-1.47, P = 0.007]. Conclusions: This case-control analysis confirmed that the FCRL3_3, FCRL3_5 and FCRL3_6 polymorphisms were associated with significantly increased risk of GO in a Chinese population.

  2. Alteration of Connective Tissue Growth Factor (CTGF) Expression in Orbital Fibroblasts from Patients with Graves’ Ophthalmopathy

    PubMed Central

    Chang, Pei-Chen; Wei, Yau-Huei

    2015-01-01

    Graves’ ophthalmopathy (GO) is a disfiguring and sometimes blinding disease, which is characterized by inflammation and swelling of orbital tissues, with fibrosis and adipogenesis being predominant features. The aim of this study is to investigate whether the expression levels of fibrosis-related genes, especially that of connective tissue growth factor (CTGF), are altered in orbital fibroblasts of patients with GO. The role of oxidative stress in the regulation of CTGF expression in GO orbital fibroblasts is also examined. By a SYBR Green-based real time quantitative PCR (RT-QPCR), we demonstrated that the mRNA expression levels of fibronectin, apolipoprotein J, and CTGF in cultured orbital fibroblasts from patients with GO were significantly higher than those of age-matched normal controls (p = 0.007, 0.037, and 0.002, respectively). In addition, the protein expression levels of fibronectin, apolipoprotein J, and CTGF analyzed by Western blot were also significantly higher in GO orbital fibroblasts (p = 0.046, 0.032, and 0.008, respectively) as compared with the control. Furthermore, after treatment of orbital fibroblasts with a sub-lethal dose of hydrogen peroxide (200 ?M H2O2), we found that the H2O2-induced increase of CTGF expression was more pronounced in the GO orbital fibroblasts as compared with those in normal controls (20% vs. 7%, p = 0.007). Importantly, pre-incubation with antioxidants including N-acetylcysteine (NAC) and vitamin C, respectively, resulted in significant attenuation of the induction of CTGF in GO orbital fibroblasts in response to H2O2 (p = 0.004 and 0.015, respectively). Taken together, we suggest that oxidative stress plays a role in the alteration of the expression of CTGF in GO orbital fibroblasts that may contribute to the pathogenesis and progression of GO. Antioxidants may be used in combination with the therapeutic agents for effective treatment of GO. PMID:26599235

  3. Alteration of Connective Tissue Growth Factor (CTGF) Expression in Orbital Fibroblasts from Patients with Graves' Ophthalmopathy.

    PubMed

    Tsai, Chieh-Chih; Wu, Shi-Bei; Chang, Pei-Chen; Wei, Yau-Huei

    2015-01-01

    Graves' ophthalmopathy (GO) is a disfiguring and sometimes blinding disease, which is characterized by inflammation and swelling of orbital tissues, with fibrosis and adipogenesis being predominant features. The aim of this study is to investigate whether the expression levels of fibrosis-related genes, especially that of connective tissue growth factor (CTGF), are altered in orbital fibroblasts of patients with GO. The role of oxidative stress in the regulation of CTGF expression in GO orbital fibroblasts is also examined. By a SYBR Green-based real time quantitative PCR (RT-QPCR), we demonstrated that the mRNA expression levels of fibronectin, apolipoprotein J, and CTGF in cultured orbital fibroblasts from patients with GO were significantly higher than those of age-matched normal controls (p = 0.007, 0.037, and 0.002, respectively). In addition, the protein expression levels of fibronectin, apolipoprotein J, and CTGF analyzed by Western blot were also significantly higher in GO orbital fibroblasts (p = 0.046, 0.032, and 0.008, respectively) as compared with the control. Furthermore, after treatment of orbital fibroblasts with a sub-lethal dose of hydrogen peroxide (200 ?M H2O2), we found that the H2O2-induced increase of CTGF expression was more pronounced in the GO orbital fibroblasts as compared with those in normal controls (20% vs. 7%, p = 0.007). Importantly, pre-incubation with antioxidants including N-acetylcysteine (NAC) and vitamin C, respectively, resulted in significant attenuation of the induction of CTGF in GO orbital fibroblasts in response to H2O2 (p = 0.004 and 0.015, respectively). Taken together, we suggest that oxidative stress plays a role in the alteration of the expression of CTGF in GO orbital fibroblasts that may contribute to the pathogenesis and progression of GO. Antioxidants may be used in combination with the therapeutic agents for effective treatment of GO. PMID:26599235

  4. Effect of Orbital Decompression on Corneal Topography in Patients with Thyroid Ophthalmopathy

    PubMed Central

    Kim, Su Ah; Jung, Su Kyung; Paik, Ji Sun; Yang, Suk-Woo

    2015-01-01

    Objective To evaluate changes in corneal astigmatism in patients undergoing orbital decompression surgery. Methods This retrospective, non randomized comparative study involved 42 eyes from 21 patients with thyroid ophthalmopathy who underwent orbital decompression surgery between September 2011 and September 2014. The 42 eyes were divided into three groups: control (9 eyes), two-wall decompression (25 eyes), and three-wall decompression (8 eyes). The control group was defined as the contralateral eyes of nine patients who underwent orbital decompression surgery in only one eye. Corneal topography (Orbscan II), Hertel exophthalmometry, and intraocular pressure were measured at 1 month before and 3 months after surgery. Corneal topographic parameters analyzed were total astigmatism (TA), steepest axis (SA), central corneal thickness (CCT), and anterior chamber depth (ACD). Results Exophthalmometry values and intraocular pressure decreased significantly after the decompression surgery. The change (absolute value (|x|) of the difference) in astigmatism at the 3 mm zone was significantly different between the decompression group and the controls (p = 0.025). There was also a significant change in the steepest axis at the 3 mm zone between the decompression group and the controls (p = 0.033). An analysis of relevant changes in astigmatism showed that there was a dominant tendency for incyclotorsion of the steepest axis in eyes that underwent decompression surgery. Using Astig PLOT, the mean surgically induced astigmatism (SIA) was 0.21±0.88 D with an axis of 46±22°, suggesting that decompression surgery did change the corneal shape and induced incyclotorsion of the steepest axis. Conclusions There was a significant change in corneal astigmatism after orbital decompression surgery and this change was sufficient to affect the optical function of the cornea. Surgeons and patients should be aware of these changes. PMID:26352432

  5. Digital Aeromagnetic Data and Derivative Products from a Helicopter Survey over the Town of Taos and Surrounding Areas, Taos County, New Mexico

    USGS Publications Warehouse

    Bankey, Viki; Grauch, V.J.S.; Fugro Airborne Surveys Corporation

    2004-01-01

    This report contains digital data, image files, and text files describing data formats and survey procedures for aeromagnetic data collected during a helicopter geophysical survey in northern New Mexico during October 2003. The survey covers the Town of Taos, Taos Pueblo, and surrounding communities in Taos County. Several derivative products from these data are also presented, including reduced-to-pole, horizontal gradient magnitude, and downward continued grids and images.

  6. Improved Website Fingerprinting on Tor Tao Wang Ian Goldberg

    E-print Network

    Goldberg, Ian

    Improved Website Fingerprinting on Tor Tao Wang Ian Goldberg Cheriton School of Computer Science fingerprinting techniques that achieve a higher classification accuracy on Tor than previous works. We describe our novel methodology for gathering data on Tor; this methodology is essential for accurate classifier

  7. Anatomy: Simple and Effective Privacy Preservation Xiaokui Xiao Yufei Tao

    E-print Network

    Zhang, Jun

    Anatomy: Simple and Effective Privacy Preservation Xiaokui Xiao Yufei Tao Department of Computer}@cse.cuhk.edu.hk ABSTRACT This paper presents a novel technique, anatomy, for publishing sen- sitive data. Anatomy releases method based on generalization. Specifically, anatomy permits aggregate reasoning with average error

  8. THE SATURATION CONJECTURE (AFTER A. KNUTSON AND T. TAO)

    E-print Network

    Buch, Anders Skovsted

    THE SATURATION CONJECTURE (AFTER A. KNUTSON AND T. TAO) WITH AN APPENDIX BY WILLIAM FULTON ANDERS. The Littlewood-Richardson coefficient c µ is defined to be the multiplicity of V in the decomposition of V Vµ.4]. In combinatorics, a triple is in Tn if and only if there exists a Littlewood- Richardson skew tableau with shape

  9. Modelling Electrical Car Diffusion Based on Agent Tao Zhang, 3

    E-print Network

    Aickelin, Uwe

    Modelling Electrical Car Diffusion Based on Agent 1 Lei Yu, ,2 Tao Zhang, 3 Siebers Peer-Ola, 4 to include things like car parking charges, price of electrical car, energy awareness and word of mouth parking rates and other incentives on the uptake of electrical cars. The goal of this case study

  10. Music Data Mining: An Introduction Tao Li and Lei Li

    E-print Network

    Li, Tao

    Music Data Mining: An Introduction Tao Li and Lei Li October 17, 2010 #12;2 #12;Contents 1 Introduction 5 1.1 Music Data Sources . . . . . . . . . . . . . . . . . . . . . . . . . 5 1.2 An Introduction and Algorithms . . . . . . . . . . . . . 11 1.3 Music Data Mining

  11. Compressive Sensing (CS) [Cands/Romberg/Tao, Donoho, 2005

    E-print Network

    Compressive Sensing (CS) [Candès/Romberg/Tao, Donoho, 2005] Sparse signal x, matrix , measurements Distributed Compressive Sensing (DCS) · Types of structure in signal ensem- bles · Intrasignal and Intersignal: Example: Sparse common and innovations Discussion ·Theorem applies to: ·joint compressive sensing (same

  12. 75 FR 71414 - Questa Ranger District, Carson National Forest; Taos County, NM; Taos Ski Valley's 2010 Master...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-23

    ... guests' demands and expectations. The proposed action is designed to address TSV's economic and... project design features, or analyze environmental effects. It is important that reviewers provide their... in the Sangre de Cristo Mountains, about 20 miles northeast of Taos, New Mexico, at the terminus...

  13. Blood-aqueous barrier integrity in patients with Graves’ Ophthalmopathy (GO), before and after rehabilitative surgery

    PubMed Central

    K?ysik, Anna; Kozakiewicz, Marcin

    2014-01-01

    Background The study was conducted to analyze aqueous flare and it’s correlations in patients with Graves’ ophthalmopathy, undergoing orbital decompression, extra-ocular muscle and eyelid surgery. Prospective interventional case series. Materials and Methods 48 eyes of 27 patients(20 female and 7 male, aged 54.4±5.7), undergoing surgical treatment for GO. 18 eyes of 9 patients (aged 55.3±3.6) undergoing orbital decompression. 19 eyes of 11 patients (aged 54.7±5.6) undergoing extraocular muscle surgery and 13 eyes of 7 patients (aged 53.9±4.9) undergoing eyelid surgery and control group (34 patients aged 53.9±5.1). Laser flare analysis, and clinical assessment was performed before surgery and 1 day, 7 days and 3 months following surgery. Results Aqueous flare was significantly higher in patients with GO (14.03 ± 8.45), before intervention than in the control group (7.89 ± 3.56) (p<0.001), and correlated with Clinical Activity Score and intraocular pressure. In the patients undergoing orbital decompression, flare increased from 17.77±10.63 pc/ms to 38.32±13.56 pc/ms on the first day, and 41.31±17.19 pc/ms on the seventh day and returned to 16.01±8.58 pc/ms in 3 months. In patients undergoing extra-ocular muscle surgery flare increased from 13.05±6.50pc/ms to 23.04±11.53 pc/ms (p<0.001) on the first day, and returned to 18.02±14.09pc/ms on the seventh day. Eyelid surgery did not change flare values. Conclusions Orbital decompression disrupts blood-aqueous barrier. The integrity of blood-aqueous barrier returns to pre-operative status within three months. Extraocular muscle surgery mildly affects blood aqueous barrier integrity, and the effect subsides within seven days. Eyelid surgery does not affect blood-aqueous barrier. PMID:25679415

  14. Status of the Transneptunian Automated Occultation Survey (TAOS II)

    NASA Astrophysics Data System (ADS)

    Lehner, Matthew; Wang, S.; Ho, P.; Zhang, Z.; Cook, K.; Yen, W.; Reyes-Ruiz, M.; Hiriart, D.; Richer, M.; Alcock, C.; Szentgyorgyi, A.; Geary, J.; Norton, T.; Furesz, G.

    2013-10-01

    The Transneptunian Automated Occultation Survey (TAOS II) will aim to detect occultations of stars by small 1 km diameter) objects in the Transneptunian region and beyond. Such events are very rare (< 10-3 events per star per year) and short in duration (˜200 ms), so many stars must be monitored at a high readout cadence. TAOS II will operate three 1.3 meter telescopes at the Observatorio Astronómico Nacional at San Pedro Mártir in Baja California, México. With a 2.3 square degree field of view and high speed cameras comprising CMOS imagers, the survey will monitor 10,000 stars simultaneously with all three telescopes at a readout cadence of 20 Hz. In this presentation, we will describe the project in detail and discuss the progress on the development of the survey infrastructure.

  15. Status of the Transneptunian Automated Occultation Survey (TAOS II)

    NASA Astrophysics Data System (ADS)

    Lehner, Matthew J.; Wang, Shiang-Yu; Alcock, Charles A.; Cook, Kem H.; Furesz, Gabor; Geary, John C.; Hiriart, David; Ho, Paul T.; Lee, William H.; Melsheimer, Frank; Norton, Timothy; Reyes-Ruiz, Mauricio; Richer, Michael; Szentgyorgyi, Andrew; Yen, Wei-Ling; Zhang, Zhi-Wei

    2014-07-01

    The Transneptunian Automated Occultation Survey (TAOS II) will aim to detect occultations of stars by small (~1 km diameter) objects in the Kuiper Belt and beyond. Such events are very rare (< 10-3 events per star per year) and short in duration (~200 ms), so many stars must be monitored at a high readout cadence. TAOS II will operate three 1.3 meter telescopes at the Observatorio Astronómico Nacional at San Pedro Mártir in Baja California, México. With a 2.3 square degree field of view and a high speed camera comprising CMOS imagers, the survey will monitor 10,000 stars simultaneously with all three telescopes at a readout cadence of 20 Hz. Construction of the site began in the fall of 2013.

  16. Status of the Transneptunian Automated Occultation Survey (TAOS II)

    NASA Astrophysics Data System (ADS)

    Lehner, M.; Wang, S.; Zhang, Z.; Ho, P.; Yen, W.; Reyes-Ruiz, M.; Richer, M.; Cook, K.; Hsu, S.; Chen, H.; Chang, Y.; Hiriart, D.; Ricci, D.; Szentgyorgyi, A.; Norton, T.; Geary, J.; Furesz, G.; Alcock, C.; Byun, Y.

    2014-07-01

    The Transneptunian Automated Occultation Survey (TAOS II) will aim to detect occultations of stars by small (˜1 km diameter) objects in the Transneptunian region and beyond. Such events are very rare (<10^{-3} events per star per year) and short in duration (˜200 ms), so many stars must be monitored at a high readout cadence. TAOS II will operate three 1.3 meter telescopes at the Observatorio Astronómico Nacional at San Pedro Mártir in Baja California, México. With a 2.3 square degree field of view and high-speed cameras comprising arrays of custom CMOS imagers, the survey will monitor 10,000 stars simultaneously with all three telescopes at a readout cadence of 20 Hz. The survey will begin operation in 2016. This poster presents an update on the status of the site preparation and the technical development.

  17. THE TAOS PROJECT: RESULTS FROM SEVEN YEARS OF SURVEY DATA

    SciTech Connect

    Zhang, Z.-W.; Lehner, M. J.; Wang, J.-H.; Wen, C.-Y.; Wang, S.-Y.; King, S.-K.; Cook, K. H.; Lee, T.; Granados, A. P.; Alcock, C.; Protopapas, P.; Axelrod, T.; Bianco, F. B.; Byun, Y.-I.; Chen, W. P.; Coehlo, N. K.; De Pater, I.; Kim, D.-W.; Lissauer, J. J.; Marshall, S. L.; and others

    2013-07-01

    The Taiwanese-American Occultation Survey (TAOS) aims to detect serendipitous occultations of stars by small ({approx}1 km diameter) objects in the Kuiper Belt and beyond. Such events are very rare (<10{sup -3} events per star per year) and short in duration ({approx}200 ms), so many stars must be monitored at a high readout cadence. TAOS monitors typically {approx}500 stars simultaneously at a 5 Hz readout cadence with four telescopes located at Lulin Observatory in central Taiwan. In this paper, we report the results of the search for small Kuiper Belt objects (KBOs) in seven years of data. No occultation events were found, resulting in a 95% c.l. upper limit on the slope of the faint end of the KBO size distribution of q = 3.34-3.82, depending on the surface density at the break in the size distribution at a diameter of about 90 km.

  18. THE SATURATION CONJECTURE (AFTER A. KNUTSON AND T. TAO)

    E-print Network

    Buch, Anders Skovsted

    THE SATURATION CONJECTURE (AFTER A. KNUTSON AND T. TAO) WITH AN APPENDIX BY WILLIAM FULTON ANDERS V â?? . The Littlewood­Richardson coefficient c Å¡ â??¯ is defined to be the multiplicity of V Å¡ if there exists a Littlewood­ Richardson skew tableau with shape Å¡=â?? and content ¯ [5, x5.2]. It is well known

  19. First Results From The Taiwanese-American Occultation Survey (TAOS)

    E-print Network

    Z. -W. Zhang; F. B. Bianco; M. J. Lehner; N. K. Coehlo; J. -H. Wang; S. Mondal; C. Alcock; T. Axelrod; Y. -I. Byun; W. -P. Chen; K. H. Cook; R. Dave; I. de Pater; R. Porrata; D. -W. Kim; S. -K. King; T. Lee; H. -C. Lin; J. J. Lissauer; S. L. Marshall; P. Protopapas; J. A. Rice; M. E. Schwamb; S. -Y. Wang; C. -Y. Wen

    2008-08-14

    Results from the first two years of data from the Taiwanese-American Occultation Survey (TAOS) are presented. Stars have been monitored photometrically at 4 Hz or 5 Hz to search for occultations by small (~3 km) Kuiper Belt Objects (KBOs). No statistically significant events were found, allowing us to present an upper bound to the size distribution of KBOs with diameters 0.5 km < D < 28 km.

  20. First Results From The Taiwanese-American Occultation Survey (TAOS)

    SciTech Connect

    Zhang, Z; Bianco, F B; Lehner, M J; Coehlo, N K; Wang, J; Mondal, S; Alcock, C; Axelrod, T; Byun, Y; Chen, W P; Cook, K H; Dave, R; de Pater, I; Porrata, R; Kim, D; King, S; Lee, T; Lin, H; Lissauer, J J; Marshall, S L; Protopapas, P; Rice, J A; Schwamb, M E; Wang, S; Wen, C

    2008-08-22

    Results from the first two years of data from the Taiwanese-American Occultation Survey (TAOS) are presented. Stars have been monitored photometrically at 4 Hz or 5 Hz to search for occultations by small ({approx}3 km) Kuiper Belt Objects (KBOs). No statistically significant events were found, allowing us to present an upper bound to the size distribution of KBOs with diameters 0.5 km < D < 28 km.

  1. 2013 European Thyroid Association Guidelines for Cervical Ultrasound Scan and Ultrasound-Guided Techniques in the Postoperative Management of Patients with Thyroid Cancer

    PubMed Central

    Leenhardt, L.; Erdogan, M.F.; Hegedus, L.; Mandel, S.J.; Paschke, R.; Rago, T.; Russ, G.

    2013-01-01

    Cervical ultrasound scanning (US) is considered a key examination, by all major thyroid and endocrine specialist societies for the postoperative follow-up of thyroid cancer patients to assess the risk of recurrence. Neck US imaging is readily available, non-invasive, relatively easy to perform, cost-effective, and can guide diagnostic and therapeutic procedures with low complication rates. Its main shortcoming is its operator-dependency. Because of the pivotal role of US in the care of thyroid cancer patients, the European Thyroid Association convened a panel of international experts to review technical aspects, indications, results, and limitations of cervical US in the initial staging and follow-up of thyroid cancer patients. The main aim is to establish guidelines for both a cervical US scanning protocol and US-guided diagnostic and therapeutic procedures in patients with thyroid cancer. This report presents (1) standardization of the US scanning procedure, techniques of US-guided fine-needle aspiration, and reporting of findings; (2) definition of criteria for classification of malignancy risk based on cervical US imaging characteristics of neck masses and lymph nodes; (3) indications for US-guided fine-needle aspiration and for biological in situ assessments; (4) proposal of an algorithm for the follow-up of thyroid cancer patients based on risk stratification following histopathological and cervical US findings, and (5) discussion of the potential use of US-guided localization and ablation techniques for locoregional thyroid metastases. PMID:24847448

  2. 77 FR 38375 - Notice of Availability of the Final Environmental Impact Statement (FEIS) for the Taos Regional...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ...Aviation Administration Notice of Availability of the Final Environmental Impact Statement (FEIS) for the Taos Regional Airport Layout Plan Improvements, Taos, NM AGENCY: Federal Aviation Administration (FAA), Department of Transportation (DOT)....

  3. Audiomagnetotelluric data, Taos Plateau Volcanic Field, New Mexico

    USGS Publications Warehouse

    Ailes, Chad E.; Rodriguez, Brian D.

    2011-01-01

    The U.S. Geological Survey is conducting a series of multidisciplinary studies of the San Luis Basin as part of the Geologic framework of the Rio Grande Basins project. Detailed geologic mapping, high-resolution airborne magnetic surveys, gravity surveys, audiomagnetotelluric surveys, and hydrologic and lithologic data are being used to better understand the aquifers. This report describes a regional east-west audiomagnetotelluric sounding profile acquired in late July 2009 across the Taos Plateau Volcanic Field. No interpretation of the data is included.

  4. Practice Trends in Patients with Persistent Detectable Thyroglobulin and Negative Diagnostic Radioiodine Whole Body Scans: A Survey of American Thyroid Association Members

    PubMed Central

    Diehl, Nancy; Bernet, Victor

    2014-01-01

    Background: Management of patients with thyroglobulin (Tg)-positive/scan-negative thyroid cancer remains challenging. American Thyroid Association (ATA) guidelines recommend potential use of empiric 131I therapy and various scanning modalities, but no standard for managing such cases exists. Methods: We surveyed ATA members to assess current practice in management of patients with Tg-positive/scan-negative disease. Members participated in a web-based survey of six case scenarios of Tg elevations but iodine scan negativity. Results: A total of 288 ATA members (80% male) participated. Patient age, sex, and basal and stimulated Tg varied between the cases. Respondents were asked their opinion regarding empiric 131I therapy use, including 131I dose, use and duration of low-iodine diet, thyroxine withdrawal or recombinant human thyrotropin (rhTSH), and utilization of additional imaging (neck ultrasound (US) or positron emission tomography/computed tomography (PET/CT)) and reconsideration of 131I therapy. Between 16% and 51% recommended initial use of empiric 131I for the various scenarios. The majority chose a 131I dose between 75 and 150 mCi, and 73% employed a low-iodine diet for two or more weeks. Preference between thyroxine withdrawal versus rhTSH was evenly split. More than 98% obtained a neck US if empiric 131I was not given; 52–89% would proceed to PET/CT if US was negative. Only 44% used rhTSH stimulation in PET scan preparation. 131I use was more common with stimulated Tg significantly >10?ng/mL. 131I therapy was slightly more likely with PET-positive (56%) than PET-negative status (45%). Respondents were split regarding empiric 131I if basal and stimulated Tg increased ?150% over two years. Providers in North America less commonly utilized 131I treatment than those from other areas. In the face of possible heterophilic antibody interference in the Tg assay, the majority did not recommend 131I therapy. Conclusions: Empiric 131I therapy is still utilized for patients with Tg-positive/scan-negative disease. Neck US is frequently used to further evaluate such cases as 18FDG-PET/CT, albeit the latter is used somewhat less often. Use of 131I therapy correlated with the degree of Tg elevation or development of Tg antibodies, and was recommended more commonly with PET-positive than PET-negative status in patients with lower Tg levels. 131I was less commonly used by providers within North America. PMID:25058708

  5. Status of the Transneptunian Automated Occultation Survey (TAOS II)

    NASA Astrophysics Data System (ADS)

    Reyes-Ruiz, Mauricio

    2014-11-01

    TAOS II is a next generation occultation survey with the goal of measuring the size distribution of the small objects (diameters between 0.5 and 30 km) in the Kuiper Belt. The project is a collaboration between the Academia Sinica Institute of Astronomy and Astrophysics, the Universidad Nacional Autonoma de Mexico, and the Harvard-Smithsonian Center for Astrophysics, The survey will operate three 1.3 m telescopes at San Pedro Martir Observatory in Baja California, Mexico. Each telescope will be equipped with a custom camera comprising a focal plane array of CMOS imagers. Each camera will be capable of reading out image data from 10,000 stars at a cadence of 20 Hz. All telescopes will monitor the same set of stars simultaneously to search for coincident occultation events while minimizing the false positive rate. This poster describes the project and reports on the progress of the development of the survey infrastructure.

  6. Genetic Profiling in Graves' Disease: Further Evidence for Lack of a Distinct Genetic Contribution to Graves' Ophthalmopathy

    PubMed Central

    Latif, Rauf; Bahn, Rebecca; Davies, Terry F.

    2012-01-01

    Background Graves' disease (GD), including Graves' ophthalmopathy or orbitopathy (GO), is an autoimmune disease with an environmental and genetic component to its etiology. The genetic contribution to the GO clinical phenotype remains unclear. Previous data from our laboratory and others have suggested that GO has no specific genetic component distinct from GD itself, while other reports have occasionally appeared suggesting that polymorphisms in genes such as CTLA4 and IL23R specifically increase the risk for GO. One of the criticisms of all these reports has been the clinical definition of the GO phenotype as distinct from hyperthyroid GD devoid of clinically significant eye involvement. The objective of this study was to take advantage of a phenotypically pure group of GD patients with GO and examine a series of genes associated with GD to determine if any were more definitively associated with GO rather than Graves' thyroid disease itself. Methods To further examine whether specific susceptibility genes are associated with GO, we have performed further genetic association studies using highly characterized GO patients, many of whom had undergone orbital decompression surgery for their exophthalmos. We genotyped HLA, CTLA4, IL23R, and TSHR genes in a group of 256 Caucasian patients with severe GO (n=199) and less severe GO (n=57), and 90 patients with GD but no clinically apparent GO. Results We found that the allele and genotype frequencies were not statistically different between GO and non-GO patients for any of the genes and gene combinations assessed. Conclusions These results provide further evidence that patients with GO do not have a distinct genetic susceptibility to their eye disease and again suggest that environmental and/or epigenetic influences are at play. PMID:22663548

  7. Genetic Associations of Interleukin-related Genes with Graves’ Ophthalmopathy: a Systematic Review and Meta-analysis

    PubMed Central

    Wong, Kah Hie; Rong, Shi Song; Chong, Kelvin K. L.; Young, Alvin L.; Pang, Chi Pui; Chen, Li Jia

    2015-01-01

    Graves’ ophthalmopathy (GO) is the commonest extra-thyroidal manifestation of Graves’ disease (GD). Associations between interleukin-related (IL) gene polymorphisms and GO have been reported in different populations. We aim to confirm such associations by conducting a meta-analysis. Totally 382 publications were retrieved in MEDLINE and EMBASE up to 25/2/2015. After removing the duplicates and assessing the studies, we retrieved 16 studies that met the selection criteria for meta-analysis, involving 12 polymorphisms in 8 IL-related genes, and 1650 GO cases and 2909 GD controls. The summary odds ratio (OR) and 95% confidence intervals (CI) were estimated. We found one polymorphism in IL1A (rs1800587, c.-889C>T) showing a suggestive association with GO in the meta-analysis (allelic model [T vs. C]: OR?=?1.62, 95% CI: 1.00–2.62, P?=?0.050, I2?=?53.7%; recessive model [TT vs. TC?+?CC]: OR?=?2.39, 95% CI: 1.07–5.37, P?=?0.039, I2?=?23.6%; heterozygous model [TC vs. CC]: OR?=?1.52, 95% CI: 1.04–2.22, P?=?0.034, I2?=?37.0%). No association with GO was detected for the other 7 genes (IL1B, IL1RA, IL4, IL6, IL12B, IL13 and IL23R). Our results thus indicate that IL1A is likely to be a genetic biomarker for GO. Further studies with larger sample sizes are warranted to confirm the associations of IL1A and other IL-related genes with GO. PMID:26578206

  8. Genetic Associations of Interleukin-related Genes with Graves' Ophthalmopathy: a Systematic Review and Meta-analysis.

    PubMed

    Wong, Kah Hie; Rong, Shi Song; Chong, Kelvin K L; Young, Alvin L; Pang, Chi Pui; Chen, Li Jia

    2015-01-01

    Graves' ophthalmopathy (GO) is the commonest extra-thyroidal manifestation of Graves' disease (GD). Associations between interleukin-related (IL) gene polymorphisms and GO have been reported in different populations. We aim to confirm such associations by conducting a meta-analysis. Totally 382 publications were retrieved in MEDLINE and EMBASE up to 25/2/2015. After removing the duplicates and assessing the studies, we retrieved 16 studies that met the selection criteria for meta-analysis, involving 12 polymorphisms in 8 IL-related genes, and 1650 GO cases and 2909 GD controls. The summary odds ratio (OR) and 95% confidence intervals (CI) were estimated. We found one polymorphism in IL1A (rs1800587, c.-889C>T) showing a suggestive association with GO in the meta-analysis (allelic model [T vs. C]: OR?=?1.62, 95% CI: 1.00-2.62, P?=?0.050, I(2)?=?53.7%; recessive model [TT vs. TC?+?CC]: OR?=?2.39, 95% CI: 1.07-5.37, P?=?0.039, I(2)?=?23.6%; heterozygous model [TC vs. CC]: OR?=?1.52, 95% CI: 1.04-2.22, P?=?0.034, I(2)?=?37.0%). No association with GO was detected for the other 7 genes (IL1B, IL1RA, IL4, IL6, IL12B, IL13 and IL23R). Our results thus indicate that IL1A is likely to be a genetic biomarker for GO. Further studies with larger sample sizes are warranted to confirm the associations of IL1A and other IL-related genes with GO. PMID:26578206

  9. Prediction of thermal acoustic oscillations (TAOs) in the CLAES solid CO2/neon system

    NASA Technical Reports Server (NTRS)

    Spradley, I. E.; Yuan, S. W. K.

    1991-01-01

    Results are presented of a study initiated to investigate the possibility that the existence of thermal acoustic oscillations (TAOs) in the Cryogenic Limb Atmospheric Etalon Spectrometer (CLAES) neon plumbing system ground configuration could be the cause of higher-than-predicted heat rates measured during thermal ground testing. Tests were conducted between warm boundary temperatures ranging from 40 to 100 K, which simulated the actual test conditions of the CLAES CO2/neon system. TAOs were observed between 6 and 106 Torr, which agreed with the analytical predictions, and verified the possible existence of TAOs in the CLAES system during ground testing. The presence of TAOs was eventually confirmed in the CLAES system during a subsequent thermal test and were determined to have caused the higher heat rates measured during the prior thermal test.

  10. TAO1 kinase maintains chromosomal stability by facilitating proper congression of chromosomes

    PubMed Central

    Shrestha, Roshan L.; Tamura, Naoka; Fries, Anna; Levin, Nicolas; Clark, Joanna; Draviam, Viji M.

    2014-01-01

    Chromosomal instability can arise from defects in chromosome–microtubule attachment. Using a variety of drug treatments, we show that TAO1 kinase is required for ensuring the normal congression of chromosomes. Depletion of TAO1 reduces the density of growing interphase and mitotic microtubules in human cells, showing TAO1's role in controlling microtubule dynamics. We demonstrate the aneugenic nature of chromosome–microtubule attachment defects in TAO1-depleted cells using an error-correction assay. Our model further strengthens the emerging paradigm that microtubule regulatory pathways are important for resolving erroneous kinetochore–microtubule attachments and maintaining the integrity of the genome, regardless of the spindle checkpoint status. PMID:24898139

  11. Influence of availability of TAO data on NCEP ocean data assimilation systems along the equatorial Pacific

    NASA Astrophysics Data System (ADS)

    Hu, Zeng-Zhen; Kumar, Arun

    2015-08-01

    It is reasonable to assume that the quality of an ocean reanalysis will depend not only on the ocean data assimilation system but also on the availability of observational data. Among the data assimilated in the tropical Pacific, observations from the Tropical Atmosphere Ocean (TAO) moored array are an important contributor. Due to various reasons, in the last couple of years, TAO had a very low data delivery rate at some of the mooring sites. In this work, we examined the influence of the availability of in situ TAO data from all 10 equatorial mooring sites in 1999-2014 by comparing ocean temperature from two data assimilation systems at National Centers for Environmental Prediction (NCEP): the Global Ocean Data Assimilation System (GODAS) and the Climate Forecast System Reanalysis (CFSR). Our working hypothesis is that missing of in situ observational data should lead to less observational constraint, and consequently, larger divergence between ocean reanalyses. Compared with periods of no in situ TAO observations, the disagreements of ocean temperature between CFSR and GODAS are indeed smaller when in situ TAO observations are available. The disagreements are largest along the thermocline due to its being the region of strongest variability. Thus, it is suggested that without the constraint of in situ TAO observations, the inconsistency between the ocean reanalyses from two NCEP data assimilation systems is larger, highlighting the contribution of TAO observations. Moreover, it is also suggested that the disagreement of ocean temperature between GODAS and CFSR is mainly caused by the difference of the models used in the assimilation systems and the impact of in situ TAO availability plays a secondary, but important role. To improve the quality of the assimilation products, it is necessary both to reduce model bias and to assimilate more high-quality data.

  12. Drosophila gene tao-1 encodes proteins with and without a Ste20 kinase domain that affect cytoskeletal architecture and cell migration differently

    PubMed Central

    Pflanz, Ralf; Voigt, Aaron; Yakulov, Toma; Jäckle, Herbert

    2015-01-01

    Tao-1, the single representative of the Sterile 20 kinase subfamily in Drosophila, is best known for destabilizing microtubules at the actin-rich cortex, regulating the cytoskeletal architecture of cells. More recently, Tao-1 was shown to act in the Salvador–Warts–Hippo pathway by phosphorylating Hippo, regulating cell growth as well as cell polarity. Here, we show that tao-1 encodes two proteins, one with the Sterile 20 kinase domain (Tao-L) and one without it (Tao-S), and that they act in an antagonistic manner. Tao-L expression causes lamellipodia-like cell protrusions, whereas Tao-S expression results in filopodia-like structures that make cells stick to the surface they attach to. Ectopic Tao-1 expression in the anterior region of Drosophila embryos results in pole cell formation as normally observed at the posterior end. Tao-S expression causes primordial germ cells (PGCs) to adhere to the inner wall of the gut primordia and prevents proper transepithelial migration to the gonads. Conversely, RNAi knockdowns of Tao-1 cause disordered migration of PGCs out of the gut epithelium, their dispersal within the embryo and cell death. The results reveal a novel function of Tao-1 in cell migration, which is based on antagonistic activities of two proteins encoded by a single gene. PMID:25589578

  13. TaO x -based resistive switching memories: prospective and challenges

    NASA Astrophysics Data System (ADS)

    Prakash, Amit; Jana, Debanjan; Maikap, Siddheswar

    2013-10-01

    Resistive switching memories (RRAMs) are attractive for replacement of conventional flash in the future. Although different switching materials have been reported; however, low-current operated devices (<100 ?A) are necessary for productive RRAM applications. Therefore, TaO x is one of the prospective switching materials because of two stable phases of TaO2 and Ta2O5, which can also control the stable low- and high-resistance states. Long program/erase endurance and data retention at high temperature under low-current operation are also reported in published literature. So far, bilayered TaO x with inert electrodes (Pt and/or Ir) or single layer TaO x with semi-reactive electrodes (W and Ti/W or Ta/Pt) is proposed for real RRAM applications. It is found that the memory characteristics at current compliance (CC) of 80 ?A is acceptable for real application; however, data are becoming worst at CC of 10 ?A. Therefore, it is very challenging to reduce the operation current (few microampere) of the RRAM devices. This study investigates the switching mode, mechanism, and performance of low-current operated TaO x -based devices as compared to other RRAM devices. This topical review will not only help for application of TaO x -based nanoscale RRAM devices but also encourage researcher to overcome the challenges in the future production.

  14. Pirfenidone attenuates IL-1?-induced COX-2 and PGE2 production in orbital fibroblasts through suppression of NF-?B activity.

    PubMed

    Choi, Youn-Hee; Back, Keum Ok; Kim, Hee Ja; Lee, Sang Yeul; Kook, Koung Hoon

    2013-08-01

    The aim of this study was to determine the effect of pirfenidone on interleukin (IL)-1?-induced cyclooxygenase (COX)-2 and prostaglandin (PG)E2 expression in orbital fibroblasts from patients with thyroid-associated ophthalmopathy (TAO). Primary cultures of orbital fibroblasts from patients with TAO (n = 4) and non-TAO subjects (n = 4) were prepared. The level of PGE2 in orbital fibroblasts treated with IL-1? in the presence or absence of pirfenidone was measured using an enzyme-linked immunosorbent assay. The effect of pirfenidone on IL-1?-induced COX-2 expression in orbital fibroblasts from patients with TAO was evaluated by reverse transcription-polymerase chain reaction (PCR) and quantitative real-time PCR analyses, and verified by Western blot. Activation of nuclear factor-?B (NF-?B) was evaluated by immunoblotting for inhibitor of ?B (I?B)? and phosphorylated I?B?, and DNA-binding activity of p50/p65 NF-?B was analyzed by electrophoretic mobility shift assay. In addition, IL-1 receptor type 1 (IL-1R1) expression was assessed by RT-PCR in IL-1?-treated cells with or without pirfenidone. Pirfenidone significantly attenuated IL-1?-induced PGE2 release in both TAO and non-TAO cells. IL-1?-induced COX-2 mRNA and protein expression decreased significantly following co-treatment with pirfenidone. IL-1?-induced I?B? phosphorylation and degradation decreased in the presence of pirfenidone and led to decreased nuclear translocation and DNA binding of the active NF-?B complex. In our system, neither IL-1? nor pirfenidone co-treatment influenced IL-1R1 expression. Our results suggest that pirfenidone attenuates the IL-1?-induced PGE2/COX-2 production in TAO orbital fibroblasts, which is related with suppression of the NF-?B activation. PMID:23664858

  15. Novel single-nucleotide polymorphisms in the calsequestrin-1 gene are associated with Graves’ ophthalmopathy and Hashimoto’s thyroiditis

    PubMed Central

    Lahooti, Hooshang; Cultrone, Daniele; Edirimanne, Senarath; Walsh, John P; Delbridge, Leigh; Cregan, Patrick; Champion, Bernard; Wall, Jack R

    2015-01-01

    Background The eye disorder associated with Graves’ disease, called Graves’ ophthalmopathy (GO), greatly reduces the quality of life in affected patients. Expression of the calsequestrin (CASQ1) protein in thyroid tissue may be the trigger for the development of eye muscle damage in patients with GO. We determined the prevalence of rs74123279, rs3747673, and rs2275703 single-nucleotide polymorphism (SNPs) in patients with autoimmune thyroid disorders, GO, Graves’ hyperthyroidism (GH), or Hashimoto’s thyroiditis (HT) and control subjects with no personal or family history of autoimmune thyroid disorders. Furthermore, we measured the concentration of the CASQ1 protein in normal and Graves’ thyroid tissue, correlating levels with parameters of the eye signs, CASQ1 antibody levels, and the CASQ1 gene polymorphism rs74123279 and rs2275703. Methods High-quality genomic DNA was isolated from fresh blood samples, assayed for identification of rs74123279, rs3747673, and rs2275703 SNPs in CASQ1 gene by MassARRAY SNP analysis using iPLEX technology of SEQUENOM. Results DNA samples from 300 patients and 106 control subjects (100 males, 306 females) with GO (n=74), GH (n=130), HT (n=96) and control subjects (n=106) were genotyped for the SNPs rs74123279, rs3747673 (n=405), and rs2275703 (n=407). The SNP rs74123279, rs3747673, and rs2275703 were identified as 1) common homozygous or wild type, 2) heterozygote, and 3) rare homozygous. Minor allele frequency for rs74123279, rs3747763, and rs2275703 were 21%, 40%, and 44%, respectively. Multiple comparisons of genotype frequency for rs74123279, rs3747763, and rs2275703 in the GO, GH, HT, and control groups showed P=0.06, 0.641, and 0.189, respectively. These results were substantiated by multiple comparison of alleles frequency for rs74123279, rs3838216, rs3747763, and rs2275703 in the GO, GH, HT, and control groups showed, P=0.36, 0.008, 0.66, and 0.05, respectively. Pairwise analysis of alleles frequency distribution in patients with GO showed significant probability for rs2275703, P=0.008. Conclusion Based on their evolutionary conservation and their significant prevalence, we suggest that CASQ1 gene SNPs rs74123279, rs3838216, and rs2275703 may be considered as genetic markers for GO. PMID:26445519

  16. The epidemiologic characteristics and clinical course of ophthalmopathy associated with autoimmune thyroid disease in Olmsted County, Minnesota.

    PubMed Central

    Bartley, G B

    1994-01-01

    Among incident cases of GO in Olmsted County, Minnesota: GO affected females six times more frequently than males (86% versus 14% of cases, respectively). The age-adjusted incidence rate was 16 cases per 100,000 population per year for females and 2.9 cases per 100,000 population for males. The peak incidence rates were bimodal, occurring in the age groups 40 to 44 years and 60 to 64 years in females and 45 to 49 years and 65 to 69 years in males. Among patients with GO, approximately 90% had Graves' hyperthyroidism, 1% had primary hypothyroidism, 3% had Hashimoto's thyroiditis, and 5% were euthyroid. Eyelid retraction was the most common ophthalmic feature of autoimmune thyroid disease, being present either unilaterally or bilaterally in more than 90% of patients at some point in their clinical course. Exophthalmos of one or both eyes affected approximately 60% of patients, restrictive extraocular myopathy was apparent in about 40% of patients, and optic nerve dysfunction occurred in either one or both eyes in 6% of patients with autoimmune thyroid disease. Only 5% of patients had the complete constellation of classic findings: eyelid retraction, exophthalmos, optic nerve dysfunction, extraocular muscle involvement, and hyperthyroidism. Upper eyelid retraction, either unilateral or bilateral, was documented in approximately 75% of patients at the time of diagnosis of GO. Lid lag also was a frequent early sign, being present either unilaterally or bilaterally in 50% of patients at the initial examination. At the time of diagnosis of GO, the most frequent ocular symptom was pain or discomfort, which affected 30% of patients. Some degree of diplopia was noted by approximately 17% of patients, lacrimation or photophobia was present in about 15% to 20% of patients, and 7.5% of patients complained of blurred vision. Decreased vision attributable to optic neuropathy was present in less than 2% of eyes at the time of diagnosis of GO. Thyroid dermopathy and acropachy accompanied GO in approximately 4% and 1% of patients, respectively. Myasthenia gravis occurred in less than 1% of patients. Superior limbic keratoconjunctivitis was documented in less than 4% of patients. The median age at the time of diagnosis of GO was 43 years (range, 8 to 88). Among patients with hyperthyroidism, 61% developed ophthalmopathy within 1 year of the onset of thyrotoxicosis. Symptoms and signs for which statistically significant changes occurred between the initial and final examinations included lacrimation, pain or ocular discomfort, photophobia, eyelid retraction, lid lag, eyelid fullness, conjunctival injection, chemosis, and exophthalmos.(ABSTRACT TRUNCATED AT 400 WORDS) Images FIGURE 1 FIGURE 2 FIGURE 3 PMID:7886878

  17. 77 FR 31036 - Notice of Availability of the Record of Decision for the Taos Resource Management Plan...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-24

    ...estate and 1.5 million acres of mineral estate administered by the BLM Taos Field Office within Colfax, Harding, Los Alamos, Mora, Rio Arriba, San Miguel, Santa Fe, Taos, and Union counties and is prepared in accordance with the National...

  18. 75 FR 66345 - Proposed Amendment of Class E Airspace; Taos, NM

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-28

    ...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant... follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp... action proposes to amend Class E airspace at Taos, NM. Decommissioning of the Ski non-directional...

  19. Congestion-aware Path Selection for Tor Tao Wang, Kevin Bauer, Clara Forero, and Ian Goldberg

    E-print Network

    Goldberg, Ian

    Congestion-aware Path Selection for Tor Tao Wang, Kevin Bauer, Clara Forero, and Ian Goldberg,ciforero,iang}@cs.uwaterloo.ca Abstract. Tor, an anonymity network formed by volunteer nodes, uses the estimated bandwidth of the nodes degrade the network's per- formance, discourage Tor adoption, and consequently reduce the size of Tor

  20. Congestion-aware Path Selection for Tor Tao Wang, Kevin Bauer, Clara Forero, and Ian Goldberg

    E-print Network

    Goldberg, Ian

    Congestion-aware Path Selection for Tor Tao Wang, Kevin Bauer, Clara Forero, and Ian Goldberg,ciforero,iang}@cs.uwaterloo.ca ABSTRACT Tor, an anonymity network formed by volunteer nodes, uses the estimated bandwidth of the nodes degrade the network's performance, discourage Tor adoption, and consequently reduce the size of Tor

  1. Rough Set Model Selection for Practical Decision Making Joseph P. Herbert JingTao Yao

    E-print Network

    Yao, JingTao

    Rough Set Model Selection for Practical Decision Making Joseph P. Herbert JingTao Yao Department}@cs.uregina.ca Abstract One of the challenges a decision maker faces is choos- ing a suitable rough set model to use for data analysis. The traditional algebraic rough set model classifies objects into three regions, namely

  2. Indexing Spatio-Temporal Data Warehouses Dimitris Papadias, Yufei Tao, Panos Kalnis, and Jun Zhang

    E-print Network

    Papadias, Dimitris

    Indexing Spatio-Temporal Data Warehouses Dimitris Papadias, Yufei Tao, Panos Kalnis, and Jun Zhang. A vital solution is the construction of a spatiotemporal data warehouse. In this paper, we describe retrieval [GBE+ 00], motion and trajectory preservation [PJT00], future location estimation [SJLL00] etc

  3. CSC2522 Course Project Michael Tao 6.1 Rendering Wet Sand

    E-print Network

    Toronto, University of

    CSC2522 Course Project Michael Tao 6.1 Rendering Wet Sand 6.1.1 Goals The primary goal of this project was to implement a method for rendering sand as a wet porous medium with water flowing into it from within PBRT. The final result was a video of sand being wetted by water particles flowing through

  4. Histology Image Classification using Supervised Classification and Multimodal Tao Meng, Lin Lin, Mei-Ling Shyu

    E-print Network

    Chen, Shu-Ching

    Histology Image Classification using Supervised Classification and Multimodal Fusion Tao Meng, Lin for biomedical images. Among such efforts, histology image classification is one of the most important areas due Subspace Projection Modeling (C- RSPM) supervised classification model for general histology image

  5. ST810 Final Report: JPEG Shang Xue, Xiang Ji, Tao Hu, Lin Su

    E-print Network

    Reich, Brian J.

    ST810 Final Report: JPEG Shang Xue, Xiang Ji, Tao Hu, Lin Su Overview and History Complex not affect the quality of the image as perceived by the human user. Eventually, the JPEG and the ISO that wrote the specification. The JPEG specification includes separate lossy

  6. TAO ET AL. VOL. XXX ' NO. XX ' 000000 ' XXXX www.acsnano.org

    E-print Network

    Zhou, Chongwu

    Mechanical and Electrical Anisotropy of Few-Layer Black Phosphorus Jin Tao, Wanfu Shen, Sen Wu,*, Lu Liu Angeles, California 90089, United States F ew-layer black phosphorus (BP) has drawn increasing interest-layer black phosphorus. We were able to identify the lattice orientations of the two-dimensional material

  7. Giving Meanings to WWW Images Heng Tao Shen Beng Chin Ooi Kian-Lee Tan

    E-print Network

    Ooi, Beng Chin

    Giving Meanings to WWW Images Heng Tao Shen Beng Chin Ooi Kian-Lee Tan Department of Computer Science National University of Singapore 3 Science Drive 2, Singapore 117543 ABSTRACT Images a rich source of image collection from which users can query. Interestingly, the semantics

  8. The cultural and ecological impacts of aboriginal tourism: a case study on Taiwan's Tao tribe.

    PubMed

    Liu, Tzu-Ming; Lu, Dau-Jye

    2014-01-01

    We show that tourism activities severely impact the ecology of Orchid Island, its natural resources, and the culture of the Tao tribe. For example, highway widening, in response to the increased traffic volumes caused by tourism, required many Pandanus trees to be cut and removed, which has placed the coconut crabs in danger of extinction. To promote eco-tourism, observation trips to observe Elegant Scops owls and Birdwing butterflies have taken place, which has affected the breeding of these two protected species. The Elegant Scops owls- and Birdwing butterflies-related tourism activities also break the "evil spirits" taboo of the Tao people and have caused the disappearance of the specifications for using traditional natural resources, causing natural ecosystems to face the threat of excessive use. In addition to promoting and advocating aboriginal tourism of the Tao people on Orchid Island, the Taiwanese government should help the Tao people to develop a management model that combines traditional regulations and tourism activities. PMID:25089246

  9. Tao-1 is a negative regulator of microtubule plus-end growth

    PubMed Central

    Liu, Tao; Rohn, Jennifer L.; Picone, Remigio; Kunda, Patricia; Baum, Buzz

    2010-01-01

    Microtubule dynamics are dominated by events at microtubule plus ends as they switch between discrete phases of growth and shrinkage. Through their ability to generate force and direct polar cell transport, microtubules help to organise global cell shape and polarity. Conversely, because plus-end binding proteins render the dynamic instability of individual microtubules sensitive to the local intracellular environment, cyto-architecture also affects the overall distribution of microtubules. Despite the importance of plus-end regulation for understanding microtubule cytoskeletal organisation and dynamics, little is known about the signalling mechanisms that trigger changes in their behaviour in space and time. Here, we identify a microtubule-associated kinase, Drosophila Tao-1, as an important regulator of microtubule stability, plus-end dynamics and cell shape. Active Tao-1 kinase leads to the destabilisation of microtubules. Conversely, when Tao-1 function is compromised, rates of cortical-induced microtubule catastrophe are reduced and microtubules contacting the actin cortex continue to elongate, leading to the formation of long microtubule-based protrusions. These data reveal a role for Tao-1 in controlling the dynamic interplay between microtubule plus ends and the actin cortex in the regulation of cell form. PMID:20647372

  10. SQLUnitGen: Test Case Generation for SQL Injection Yonghee Shin, Laurie Williams, Tao Xie

    E-print Network

    Young, R. Michael

    SQLUnitGen: Test Case Generation for SQL Injection Detection Yonghee Shin, Laurie Williams, Tao Xie be classified as input manipulation, such as SQL injection, cross site scripting, and buffer overflows detection, and automatic testing. We propose an approach for SQL injection vulnerability detection

  11. Dual Contouring of Hermite Data Tao Ju, Frank Losasso, Scott Schaefer, Joe Warren

    E-print Network

    Warren, Joe

    Dual Contouring of Hermite Data Tao Ju, Frank Losasso, Scott Schaefer, Joe Warren Rice University, contouring, crack prevention, quadratic error functions, polyhedral simplification e-mail: {jutao,losasso,sschaefe,jwarren}@rice the number of polygons in our model and often overwhelmed the graphics card used for the game. #12;In

  12. Dual Contouring of Hermite Data Tao Ju, Frank Losasso, Scott Schaefer, Joe Warren

    E-print Network

    Ju, Tao

    Dual Contouring of Hermite Data Tao Ju, Frank Losasso, Scott Schaefer, Joe Warren Rice University, contouring, crack prevention, quadratic error functions, polyhedral simplification e-mail: {jutao,losasso,sschaefe,jwarren}@rice the number of polygons in our model and often overwhelmed the graphics card used for the game. Copyright

  13. The TAOS Project Stellar Variability II. Detection of 15 Variable Stars

    SciTech Connect

    Mondal, S; Lin, C C; Zhang, Z W; Alcock, C; Axelrod, T; Bianco, F B; Byun, Y I; Coehlo, N K; Cook, K H; Dave, R; Kim, D W; King, S K; Lee, T; Lehner, M J; Lin, H C; Marshall, S L; Protopapas, P; Rice, J A; Schwamb, M E; Wang, J H; Wang, S Y; Wen, C Y

    2010-01-28

    The Taiwanese-American Occultation Survey (TAOS) project has collected more than a billion photometric measurements since 2005 January. These sky survey data - covering timescales from a fraction of a second to a few hundred days - are a useful source to study stellar variability. A total of 167 star fields, mostly along the ecliptic plane, have been selected for photometric monitoring with the TAOS telescopes. This paper presents our initial analysis of a search for periodic variable stars from the time-series TAOS data on one particular TAOS field, No. 151 (RA = 17{sup h} 30{sup m} 6.67{sup s}, Dec = 27 degrees, 17 minutes, 30 seconds, J2000), which had been observed over 47 epochs in 2005. A total of 81 candidate variables are identified in the 3 square degree field, with magnitudes in the range 8 < R < 16. On the basis of the periodicity and shape of the lightcurves, 32 variables, 18 of which were previously unknown, are classified as RR Lyrae, Cepheid, {delta} Scuti, SX Phonencis, semi-regular and eclipsing binaries.

  14. TAO, Vol. 10, No. 4, 719-736, December 1999 Development of an Integrated Earthquake Early Warning System in

    E-print Network

    Wu, Yih-Min

    the Ryukyu trench. The Eurasia plate sub- #12;TAO, Vol. 10, No. 4, December 1999720 ducts eastward under, the most severe damage occurred in the Taipei metropolitan areas on the western side of the island due

  15. Two Early Gamma-ray Bursts Optical Afterglow Detections with TAOS Telescopes--GRB 071010B and GRB 071112C

    SciTech Connect

    Huang, K. Y.; Wang, S. Y.; Urata, Y.

    2009-05-25

    We present on two early detections of GRB afterglows with the Taiwanese-American Occltation Sruvey (TAOS) telescopes. The robotic TAOS system has been devised so that the routine Kuiper Belt Object (KBO) survey is interrupted when a GRB alert is triggered. Our first detection, GRB 071010B was detected by TAOS 62 s after the burst and showed a weak early brightening during the observations. No significant correction with the prompt gamma-ray emission indicated that our optical emission detected is afterglow emission. The second detection of TAOS, GRB 071112C was detected 96 s after the burst, also showed a possible initial raising then followed a steep decay in the R-band light curve.

  16. Problematic Occurrence of Tyrosine Crystals in the Thai Soybean Paste Tao Chieo

    PubMed Central

    Flegel, T. W.; Bhumiratana, A.; Srisutipruti, A.

    1981-01-01

    In a Bangkok soy sauce factory that had recently converted to controlled inoculum and incubation for the koji stage of fermentation, a problem arose with unsightly white particles in the soybean paste condiment called tao chieo. This problem had not arisen during the previous history of the factory where the koji stage of the fermentation was uncontrolled. Microscopic examination of the particles showed that they were crystalline. Physical separation of the crystals followed by solvent extraction, recrystallization, chemical characterization, and spectroscopy showed that they consisted of tyrosine. Tao chieo prepared by using low- or high-protease strains of Aspergillus sp. indicated that the tyrosine crystals resulted from mold proteolysis of the soybean substrate. Addition of polyethylene glycol at the beginning of the moromi fermentation reduced the severity of crystal formation. Images PMID:16345734

  17. doi: 10.3319/TAO.2014.03.27.01(T) * Corresponding author

    E-print Network

    Wu, Yih-Min

    doi: 10.3319/TAO.2014.03.27.01(T) * Corresponding author E-mail: drymwu@ntu.edu.tw Terr. Atmos , Da-Yi Chen1, 3 , Kai-Shyr Wang4 , Ya-Ting Chan1 , Wen-Yen Chang5 , Wei-Sen Li6 , and Shaw-Hsung Ker6: Earthquake, Damage earthquake, Shaking map, MEMS accelerometer Citation: Hsieh, C. Y., Y. M. Wu, T. L. Chin

  18. Curanderismo in Taos County, New Mexico—A Possible Case of Anthropological Romanticism?

    PubMed Central

    Scheper-Hughes, Nancy; Stewart, David

    1983-01-01

    Interviews with 25 Spanish-Americans of Taos County, New Mexico, indicate that time and acculturation have greatly eroded the belief in and practice of curanderismo, the traditional folk medical system of the Southwest. Curanderismo in northern New Mexico today has moved from being a primary and important source of medical care to one used alternatively and very occasionally in cases of pediatric disorders, chronic illnesses and pain, and for those maladies still classified according to the traditional folk beliefs. PMID:6666104

  19. Radionuclide concentrations in soils and produce from Cochiti, Jemez, Taos, and San Ildefonso Pueblo Gardens

    SciTech Connect

    Fresquez, P.R.; Armstrong, D.R.; Salazar, J.G.

    1995-05-01

    Radionuclide ({sup 3}H, {sup 90}Sr, {sup 137}Cs, {sup 238}Pu, {sup 239}Pu, and total uranium) concentrations were determined in soils and produce collected from Cochiti, Jemez, Taos, and San Ildefonso Pueblo gardens. All radionuclides in soils from Pueblo areas were within or just above regional statistical (natural and/or worldwide fallout) reference levels. Similarily, the average levels of radionuclides in produce collected from Cochiti, Jemez, Taos, and San Ildefonso Pueblo gardens were not significantly different in produce collected from regional (background) locations. The effective (radiation) dose equivalent from consuming 352 lb of produce from Cochiti, Jemez, Taos, and San Ildefonso, after natural background has been subtracted, was 0.036 ({+-}0.016), 0.072 ({+-}0.051), 0.012 ({+-}0.027), and 0.110 ({+-}0.102) mrem/yr, respectively. The highest calculated dose, based on the mean + 2 std dev (95% confidence level), was 0.314 mrem/yr; this was <0.4% of the International Commission on Radiological Protection permissible dose limit for protecting members of the public.

  20. UPLC-QTOF-MS with chemical profiling approach for rapidly evaluating chemical consistency between traditional and dispensing granule decoctions of Tao-Hong-Si-Wu decoction

    PubMed Central

    2012-01-01

    Background In the present study, chemical consistency between traditional and dispensing granule decoctions of Tao-Hong-Si-Wu decoction was rapidly evaluated by UPLC-QTOF-MS coupled with the MarkerLynx software. Two different kinds of decoctions, namely traditional decoction: water extract of mixed six constituent herbs of Tao-Hong-Si-Wu decoction, and dispensing granules decoction: mixed water extract of each individual herbs of Tao-Hong-Si-Wu decoction, were prepared. Results Chemical difference was found between traditional and dispensing granule decoctions, and albiflorin, paeoniflorin, gallic acid, amygdalin, and hydroxysafflor yellow A were identified as the significantly changed components during decocting Tao-Hong-Si-Wu decoction. All the peaks of mass spectrum from Tao-Hong-Si-Wu decoction and each herb were extracted and integration by using QuanLynx™. And the optimized data was used for linear regression analysis. The contribution of each herb in Tao-Hong-Si-Wu decoction, and the optimal compatibility proportion of dispensing granule decoction were derived from the linear regression equation. Conclusions The optimal dosage proportionality of Tao-Hong-Si-Wu dispensing granule decoction was obtained as 2.5:0.2:1:0.5:0.6:0.1 (DG : CX : BS : SD : TR : HH), which guided better clinic application of Tao-Hong-Si-Wu decoction as dispensing granule decoctions usage, and it also provided some experimental data to reveal the compatibility rule of the relative TCM formulae. PMID:23176049

  1. LANL:CPO: Los Alamos National Laboratory Impacts and Investments in Taos County LA-UR 11-02376 (2/13/13)

    E-print Network

    , Student Internships, Teacher and Faculty Professional Development, and Public Understanding of Science County. Students and teachers from the Taos and Penasco School Districts participated in one or more Alamos Employees' Scholarship Fund" Gold" Recipient is George Torres from Taos High School. The amount

  2. Autoimmune thyroiditis associated with neuromyelitis optica (NMO)

    PubMed Central

    Sudulagunta, Sreenivasa Rao; Sodalagunta, Mahesh Babu; Khorram, Hadi; Sepehrar, Mona; Gonivada, Jayadevappa; Noroozpour, Zahra; Prasad, Nagendra

    2015-01-01

    Neuromyelitis optica (NMO or Devic’s syndrome) is a rare relapsing demyelinating disease of the central nervous system (CNS) that mainly affects the spinal cord and optic nerves and shares many clinical and radiological features with multiple sclerosis. The association of NMO with other autoimmune diseases was reported, but very few reports described association with autoimmune thyroid disease. Early differentiation between NMO and multiple sclerosis is very important as the natural course and treatment regimens differ significantly. We report a case of a 50-year-old woman who was admitted initially with vomiting, hiccups and paraesthesias but was not diagnosed with NMO and presented with a severe progression of the disease. The patient was also diagnosed to have autoimmune thyroiditis with lymphocytic infiltration of the thyroid which progressed from hyperthyroidism to hypothyroidism. NMO diagnosis was established with seropositivity for NMO-IgG and MRI showing longitudinally extensive spinal cord lesions (3 or more spinal segments). In spite of treatment, the response was poor due to lack of early diagnosis and aggressive immunosuppressant therapy. PMID:26633965

  3. Autoimmune thyroiditis associated with neuromyelitis optica (NMO).

    PubMed

    Sudulagunta, Sreenivasa Rao; Sodalagunta, Mahesh Babu; Khorram, Hadi; Sepehrar, Mona; Gonivada, Jayadevappa; Noroozpour, Zahra; Prasad, Nagendra

    2015-01-01

    Neuromyelitis optica (NMO or Devic's syndrome) is a rare relapsing demyelinating disease of the central nervous system (CNS) that mainly affects the spinal cord and optic nerves and shares many clinical and radiological features with multiple sclerosis. The association of NMO with other autoimmune diseases was reported, but very few reports described association with autoimmune thyroid disease. Early differentiation between NMO and multiple sclerosis is very important as the natural course and treatment regimens differ significantly. We report a case of a 50-year-old woman who was admitted initially with vomiting, hiccups and paraesthesias but was not diagnosed with NMO and presented with a severe progression of the disease. The patient was also diagnosed to have autoimmune thyroiditis with lymphocytic infiltration of the thyroid which progressed from hyperthyroidism to hypothyroidism. NMO diagnosis was established with seropositivity for NMO-IgG and MRI showing longitudinally extensive spinal cord lesions (3 or more spinal segments). In spite of treatment, the response was poor due to lack of early diagnosis and aggressive immunosuppressant therapy. PMID:26633965

  4. TAOS: Taiwan-American Occultation Survey of Comet-Sized Objects in the Kuiper Belt

    NASA Technical Reports Server (NTRS)

    Lissauer, Jack; DeVincenzi, Donald (Technical Monitor)

    1999-01-01

    Several dozen minor planets with radii greater than 100 km have been detected beyond Neptune using large telescopes. The TAOS project is to measure directly the number of these KBOs (Kuiper Belt Objects) down to the typical size of cometary nuclei (a few km) and out as far as approximately 100 AU from the Sun. Because of their large distance, small sizes and presumed low albedos, these target objects are extremely faint. Three 50 cm wide field robotic telescopes with 2048 x 2048 CCD cameras will be deployed along a 7 km east-west baseline in or near Jade Mountain National Park in Taiwan. They will monitor approximately 3000 stars for occultations by KBOs in a coincidence mode, so that the sequence and timing of the three separate blinkings can be used to distinguish real events from false alarms. Follow-up imaging observations using large telescopes will yield albedos and orbits for some of the larger objects detected by TAOS. A fourth telescope on a north-south spur to refine the size information on occulting GABON is also being contemplated.

  5. TAO, Vol. 16, No. 2, 285-314, June 2005 A Review on the Western North Pacific Monsoon

    E-print Network

    Li, Tim

    285 TAO, Vol. 16, No. 2, 285-314, June 2005 REVIEW A Review on the Western North Pacific Monsoon and evolution charac- teristics of the western North Pacific monsoon on various time scales, in- cluding its-70-day) bands. On the interannual time scale, the monsoon is greatly modulated by and possibly feeds back

  6. TAO, Vol. 16, No. 5, 1097-1120, December 2005 Characteristic Trace Fossils from Shoreface to Offshore Environments

    E-print Network

    Chen, Wen-Shan

    1097 TAO, Vol. 16, No. 5, 1097-1120, December 2005 Characteristic Trace Fossils from Shoreface words: Trace fossil, Oligocene, Hsuehshan Range, Sea-level fluctuation) 1. INTRODUCTION Oligocene fluvial and shallow marine deposits containing a diverse assemblage of body fossils as well as physical

  7. Coherent detection in optical fiber systems , Alan Pak Tao Lau, Daniel J. F. Barros, Joseph M. Kahn

    E-print Network

    Kahn, Joseph M.

    and optical communications; (060.1660) Coherent communications; (060.2920) Homodyning; (060.4080) ModulationCoherent detection in optical fiber systems Ezra Ip* , Alan Pak Tao Lau, Daniel J. F. Barros has renewed interest in coherent detection. We review detection methods, including noncoherent

  8. Two Heads are Better than Two Tapes Tao Jiang, Joel I. Seiferas, and Paul M. B. Vit anyi

    E-print Network

    Vitanyi, Paul M.B.

    Two Heads are Better than Two Tapes Tao Jiang, Joel I. Seiferas, and Paul M. B. Vit#19; anyi Mc-376. We thank Wolfgang Maass for discussions that contributed to an early version of the Anti- Holography" that are multidimensional , Paul has shown that it is [Pa84]. His proof involves using the two-head tape to write

  9. Glass Object Localization by Joint Inference of Boundary and Depth Tao Wang, Xuming He, and Nick Barnes

    E-print Network

    He, Xuming

    Glass Object Localization by Joint Inference of Boundary and Depth Tao Wang, Xuming He, and Nick.he, nick.barnes}@nicta.com.au Abstract We address the problem of localizing glass objects with multi, and build a Markov Random Field that pre- dicts glass boundary and region jointly. Based on the localization

  10. Breaking waves: Bifurcations leading to a singular wave state W. Tao Shi, Christopher L. Goodridge, and Daniel P. Lathrop*

    E-print Network

    Lathrop, Daniel P.

    Breaking waves: Bifurcations leading to a singular wave state W. Tao Shi, Christopher L. Goodridge 1996 We examine free surface wave singularities that show a violent focusing of energy. Periodic, modulated, and frequency locked wave states lead to a state with fluid spikes. When the excitation of free

  11. Security Issues in the Border Gateway Protocol (BGP) Evangelos Kranakis P.C. van Oorschot Tao Wan

    E-print Network

    Kranakis, Evangelos

    Security Issues in the Border Gateway Protocol (BGP) Evangelos Kranakis P.C. van Oorschot Tao Wan functioning. The Border Gateway Protocol (BGP) is the standard and only inter-domain routing protocol used the government may play in helping to address security issues in BGP. 1 #12;Contents 1 Introduction 4 2

  12. TAO, Vol. 14, No. 3, 1-10, September 2003 Earthquake Clustering Relative to Lunar Phases in Taiwan

    E-print Network

    Lin, Cheng-Horng

    earthquakes on the global scale (Shlien and Toksoz 1970; Heaton 1982; Palumbo 1986), or even smaller onesTAO, Vol. 14, No. 3, 1-10, September 2003 Earthquake Clustering Relative to Lunar Phases in Taiwan-1991 was converted to lunar time to reassess the notion that some earthquakes may be triggered by tidal forces

  13. TAO, Vol. 14, No. 3, 289-298, September 2003 Earthquake Clustering Relative to Lunar Phases in Taiwan

    E-print Network

    Chen, Yuh-Ing

    significant correlation between tidal forces and larger earthquakes on the global scale (Shlien and ToksozTAO, Vol. 14, No. 3, 289-298, September 2003 Earthquake Clustering Relative to Lunar Phases for the period of 1973-1991 was converted to lunar time to reassess the notion that some earthquakes may

  14. Conductivity of a suspension of nanowires in a weakly conducting medium Tao Hu, A. Yu. Grosberg, and B. I. Shklovskii

    E-print Network

    Minnesota, University of

    Conductivity of a suspension of nanowires in a weakly conducting medium Tao Hu, A. Yu. Grosberg 2006 We study the macroscopic electrical conductivity of a composite made of straight or coiled nanowires suspended in a poorly conducting medium. We assume that the volume fraction of the wires is so

  15. PHILOSOPHY (I-LI) VERSUS PHILOLOGY (K'AO-CHENG): THE JEN-HSIN TAO-HSIN DEBATE*

    E-print Network

    Elman, Benjamin

    matter-of-factly: [The human mind] is precarious and thus hard to pacify. [The moral mind] is subtle of the Confucian Classics. In particular, we will focus on the famous jen-hsin Tao-hsin [the human mind and the moral mind] passage in the "Ta Yi mo" * [Counsels of Yi the Great] chapter of the Shu

  16. Arabidopsis TAO1 is a TIR-NB-LRR protein that contributes to disease resistance induced by

    E-print Network

    Dangl, Jeff

    . Dangl, March 4, 2008 (sent for review August 12, 2007) The type III effector protein encoded effector avirulence protein encoded by avirulence gene Rpm1 (AvrRpm1) also activates RPM1. AvrB contributes in response to Pto (P. syringae pathovars tomato) DC3000(avrB), but not against Pto DC3000(avrRpm1). The tao1

  17. Quartetbased phylogeny reconstruction from gene orders # Tao Liu 1 , Jijun Tang 2 , and Bernard M.E. Moret 1

    E-print Network

    Moret, Bernard

    solving the difficult problems posed by the manipulations of these gene orders [16]. Studies conductedQuartet­based phylogeny reconstruction from gene orders # Tao Liu 1 , Jijun Tang 2 , and Bernard M reconstruction based on gene rearrangements is attract­ ing increasing attention from biologists and computer

  18. Cation exchange in a 3D perovskite-synthesis of Ni(0.5)TaO?.

    PubMed

    Amano Patino, Midori; Smith, Thomas; Zhang, Weiguo; Halasyamani, P Shiv; Hayward, Michael A

    2014-08-01

    Reaction of NiCl2 with NaTaO3 leads the formation of the perovskite phase Ni(0.5)TaO3, via a topochemical nickel-for-sodium cation exchange in which the framework of apex-linked TaO6 octahedra present in the parent phase is retained. Neutron powder diffraction data indicate Ni(0.5)TaO3 adopts a structure analogous to the paraelectric phase of LiTaO3, with triclinic P1 crystallographic symmetry. Although Ni(0.5)TaO3 has features which make it a good candidate phase for magnetoelectric multiferroic behavior, the phase remains paramagnetic in the temperature range 15 < T (K) < 300, and detailed crystallographic characterization and analysis of SHG activity indicate it retains a centrosymmetric structure down to the lowest temperatures measured (5 K). Topochemical cation exchange reactions of 3D perovskite oxides offer the opportunity to prepare a wide range of novel metastable phases in a rational manner with a high degree of synthetic control. PMID:25050865

  19. Estimating Phosphorous Load from a Large Watershed in the Great Lakes Basin Weichun Tao, Carlo DeMarchi,

    E-print Network

    and Water Assessment Tool [9] or Agricultural Nonpoint Source Pollution Model [10]. According to Quilbé etEstimating Phosphorous Load from a Large Watershed in the Great Lakes Basin Weichun Tao, Carlo De in the draining basin is the major cause of river, lake, and swamp eutrophication. Consequently, estimating

  20. Dr. Ping Liu's earlier publications 1. Ping Liu, Qingyu Yang, Xu Wang, Aiping Feng, Tao Yang, Rong Yang, Pengyun Wang,

    E-print Network

    Dr. Ping Liu's earlier publications 1. Ping Liu, Qingyu Yang, Xu Wang, Aiping Feng, Tao Yang, Rong, 2008, 128: 1418-1422. 2. Ping Liu, Shouyan Zhang, Qi Yao, Xiangyang Liu, Xu Wang, Kai Xiong, Jiayun Liu on Chromosome 1p31.3-p31.1. Human Genetics, 2008, 123: 507-513. 3. Ping Liu, Hu Li, Xiang Ren, Hai Yan Mao

  1. The size of smallest subnanometric voids estimated by positron annihilation method. Correction to the Tao-Eldrup model

    NASA Astrophysics Data System (ADS)

    Zgardzi?ska, B.

    2015-02-01

    The Tao-Eldrup model, commonly applied in estimation of free volume sizes in solids, uses the concept of infinitely deep potential well, which can lead to inaccuracies when the ortho-positronium (o-Ps) lifetime is very short (less than 1.5 ns). A simple correction allowing to estimate properly the free volume radii at the o-Ps lifetime down to 0.8 ns is proposed.

  2. ANIR: Atacama near-infrared camera for the 1.0 m miniTAO telescope

    NASA Astrophysics Data System (ADS)

    Konishi, Masahiro; Motohara, Kentaro; Tateuchi, Ken; Takahashi, Hidenori; Kitagawa, Yutaro; Kato, Natsuko; Sako, Shigeyuki; Uchimoto, Yuka K.; Toshikawa, Koji; Ohsawa, Ryou; Yamamuro, Tomoyasu; Asano, Kentaro; Ita, Yoshifusa; Kamizuka, Takafumi; Komugi, Shinya; Koshida, Shintaro; Manabe, Sho; Matsunaga, Noriyuki; Minezaki, Takeo; Morokuma, Tomoki; Nakashima, Asami; Takagi, Toshinobu; Tanabé, Toshihiko; Uchiyama, Mizuho; Aoki, Tsutomu; Doi, Mamoru; Handa, Toshihiro; Kato, Daisuke; Kawara, Kimiaki; Kohno, Kotaro; Miyata, Takashi; Nakamura, Tomohiko; Okada, Kazushi; Soyano, Takao; Tamura, Yoichi; Tanaka, Masuo; Tarusawa, Ken'ichi; Yoshii, Yuzuru

    2015-02-01

    We have developed a near-infrared camera called ANIR (Atacama Near-InfraRed camera) for the University of Tokyo Atacama Observatory 1.0 m telescope (miniTAO) installed at the summit of Cerro Chajnantor (5640 m above sea level) in the north of Chile. The camera provides a field of view of 5{^'.}1 × 5{^'.}1 with a spatial resolution of 0{^''.}298 pixel-1 in the wavelength range of 0.95 to 2.4 ?m, using Offner relay optics and a PACE HAWAII-2 focal plane array. Taking advantage of the dry site, the camera is capable of narrow-band imaging observations at the hydrogen Paschen-? (Pa?, ? = 1.8751 ?m in air) wavelength ground-based observations of which have been quite difficult due to deep atmospheric absorption, mainly from water vapor. We have been successfully obtaining Pa? images of Galactic objects and nearby galaxies since the first-light observation in 2009 with ANIR. The throughputs at the narrow-band filters (N1875, N191) including the atmospheric absorption show larger dispersion (˜ 10%) than those at broad-band filters (a few percent), indicating that they are affected by temporal fluctuations in precipitable water vapor (PWV) above the site. We evaluate the PWV content via the atmospheric transmittance at the narrow-band filters, and deduce that the median and the dispersion of the distribution of the PWV are 0.40 ± 0.30 and 0.37 ± 0.21 mm, for the N1875 and N191 data respectively, which are remarkably smaller (49% ± 38% for N1875 and 59% ± 26% for N191) than radiometry measurements at the base of Cerro Chajnantor (an altitude of 5100 m). The decrease in PWV can be explained by the altitude of the site when we assume that the vertical distribution of the water vapor is approximated at an exponential profile with scale heights within 0.3-1.9 km (previously observed values at night). We thus conclude that miniTAO/ANIR at the summit of Cerro Chajnantor indeed provides us an excellent capability for a ground-based Pa? observation.

  3. ANIR : Atacama Near-Infrared Camera for the 1.0-m miniTAO Telescope

    E-print Network

    Konishi, Masahiro; Tateuchi, Ken; Takahashi, Hidenori; Kitagawa, Yutaro; Kato, Natsuko; Sako, Shigeyuki; Uchimoto, Yuka K; Toshikawa, Koji; Ohsawa, Ryou; Yamamuro, Tomoyasu; Asano, Kentaro; Ita, Yoshifusa; Kamizuka, Takafumi; Komugi, Shinya; Koshida, Shintaro; Manabe, Sho; Matsunaga, Noriyuki; Minezaki, Takeo; Morokuma, Tomoki; Nakashima, Asami; Takagi, Toshinobu; Tanabé, Toshihiko; Uchiyama, Mizuho; Aoki, Tsutomu; Doi, Mamoru; Handa, Toshihiro; Kato, Daisuke; Kawara, Kimiaki; Kohno, Kotaro; Miyata, Takashi; Nakamura, Tomohiko; Okada, Kazushi; Soyano, Takao; Tamura, Yoichi; Tanaka, Masuo; Tarusawa, Ken'ichi; Yoshii, Yuzuru

    2015-01-01

    We have developed a near-infrared camera called ANIR (Atacama Near-InfraRed camera) for the University of Tokyo Atacama Observatory 1.0m telescope (miniTAO) installed at the summit of Cerro Chajnantor (5640 m above sea level) in northern Chile. The camera provides a field of view of 5'.1 $\\times$ 5'.1 with a spatial resolution of 0".298 /pixel in the wavelength range of 0.95 to 2.4 $\\mu$m. Taking advantage of the dry site, the camera is capable of hydrogen Paschen-$\\alpha$ (Pa$\\alpha$, $\\lambda=$1.8751 $\\mu$m in air) narrow-band imaging observations, at which wavelength ground-based observations have been quite difficult due to deep atmospheric absorption mainly from water vapor. We have been successfully obtaining Pa$\\alpha$ images of Galactic objects and nearby galaxies since the first-light observation in 2009 with ANIR. The throughputs at the narrow-band filters ($N1875$, $N191$) including the atmospheric absorption show larger dispersion (~10%) than those at broad-band filters (a few %), indicating that ...

  4. Search for Small Trans-Neptunian Objects by the TAOS Project

    SciTech Connect

    Chen, Wen-Ping; Alcock, C.; Axelrod, T.; Bianco, F.B.; Byun, Y.I.; Chang, Y.H.; Cook, K.H.; Dave, R.; Giammarco, J.; Kim, D.W.; King, S.K.; Lee, T.; Lehner, M.; Lin, C.C.; Lin, H.C.; Lissauer, J.J.; Marshall, S.; Meinshausen, N.; Mondal, S.; de Pater, I.; Porrata, R.; /Taiwan, Natl. Central U. /Harvard-Smithsonian Ctr. Astrophys. /Arizona U. /Yonsei U. /LLNL, Livermore /Pennsylvania U. /Taipei, Inst. Astron. Astrophys. /NASA, Ames /SLAC /UC, Berkeley /Caltech

    2006-12-04

    The Taiwan-America Occultation Survey (TAOS) aims to determine the number of small icy bodies in the outer reach of the Solar System by means of stellar occultation. An array of 4 robotic small (D=0.5 m), wide-field (f/1.9) telescopes have been installed at Lulin Observatory in Taiwan to simultaneously monitor some thousand of stars for such rare occultation events. Because a typical occultation event by a TNO a few km across will last for only a fraction of a second, fast photometry is necessary. A special CCD readout scheme has been devised to allow for stellar photometry taken a few times per second. Effective analysis pipelines have been developed to process stellar light curves and to correlate any possible flux changes among all telescopes. A few billion photometric measurements have been collected since the routine survey began in early 2005. Our preliminary result of a very low detection rate suggests a deficit of small TNOs down to a few km size, consistent with the extrapolation of some recent studies of larger (30-100 km) TNOs.

  5. Mid-infrared Monitoring Observations of Circumstellar Disks with TAO/MIMIZUKU

    NASA Astrophysics Data System (ADS)

    Sako, Shigeyuki; Miyata, Takashi; Kamizuka, Takafumi; Nakamura, Tomohiko; Asano, Kentaro; Uchiyama, Mizuho; Okada, Kazushi; Onaka, Takashi; Sakon, Itsuki; Kataza, Hirokazu; Yoshii, Yuzuru

    2013-07-01

    Mid-infrared variabilities of dust continuum and features in time scale of days to years have been found in circumstellar disks around YSOs and debris disks by multi-epoch studies with recent space missions such as AKARI, WISE, Spitzer, and Herschel (e.g., Dahm+09, Espaillat+11, Flaherty+12, Melis+12). However, physical mechanisms leading to the rapid MIR variabilities are still unclear because of sparse data sampling. More frequent and long-term observations with ground-based MIR instruments are required. Meanwhile, fast fluctuation of atmospheric water vapor affects photometric accuracy in the MIR observations from the ground. In order to monitor the variabilities of a few percent level as detected by the space telescopes, improvements of observation methods are needed. We have been developing a new MIR instrument MIMIZUKU (Kamizuka+12, Miyata+10) mounted on 6.5-m TAO telescope (Yoshii+10), which will be constructed at a 5,640-m altitude site in Atacama, Chile, and 8.2-m Subaru telescope in Hawaii. The MIMIZUKU has unique equipment called Field Stacker which enables simultaneous observations of target and reference objects owing to focusing two separated field-of-views on a same detector. The simultaneity improves the photometric accuracy and realizes stable long-term monitoring. We will carry out MIR monitoring observations of dust emission from the circumstellar disks and the debris disks with the imaging and low-resolution spectroscopic modes of the MIMIZUKU. The time-variable emissions from the YSOs could allow us to reveal formation and destruction mechanism of dust grains in the inner disk region. In observations of debris disks, fresh dust formed by large collisions in a planetary disk is expected to be detected.

  6. Arabidopsis TAO1 is a TIR-NB-LRR protein that contributes to disease resistance induced by the Pseudomonas syringae effector AvrB.

    PubMed

    Eitas, Timothy K; Nimchuk, Zachary L; Dangl, Jeffery L

    2008-04-29

    The type III effector protein encoded by avirulence gene B (AvrB) is delivered into plant cells by pathogenic strains of Pseudomonas syringae. There, it localizes to the plasma membrane and triggers immunity mediated by the Arabidopsis coiled-coil (CC)-nucleotide binding (NB)-leucine-rich repeat (LRR) disease resistance protein RPM1. The sequence unrelated type III effector avirulence protein encoded by avirulence gene Rpm1 (AvrRpm1) also activates RPM1. AvrB contributes to virulence after delivery from P. syringae in leaves of susceptible soybean plants, and AvrRpm1 does the same in Arabidopsis rpm1 plants. Conditional overexpression of AvrB in rpm1 plants results in leaf chlorosis. In a genetic screen for mutants that lack AvrB-dependent chlorosis in an rpm1 background, we isolated TAO1 (target of AvrB operation), which encodes a Toll-IL-1 receptor (TIR)-NB-LRR disease resistance protein. In rpm1 plants, TAO1 function results in the expression of the pathogenesis-related protein 1 (PR-1) gene, suggestive of a defense response. In RPM1 plants, TAO1 contributes to disease resistance in response to Pto (P. syringae pathovars tomato) DC3000(avrB), but not against Pto DC3000(avrRpm1). The tao1-5 mutant allele, a stop mutation in the LRR domain of TAO1, posttranscriptionally suppresses RPM1 accumulation. These data provide evidence of genetically separable disease resistance responses to AvrB and AvrRpm1 in Arabidopsis. AvrB activates both RPM1, a CC-NB-LRR protein, and TAO1, a TIR-NB-LRR protein. These NB-LRR proteins then act additively to generate a full disease resistance response to P. syringae expressing this type III effector. PMID:18424557

  7. Upper Limits on the Number of Small Bodies in Sedna-Like Orbits by the TAOS Project

    SciTech Connect

    Wang, J; Lehner, M J; Zhang, Z; Bianco, F B; Alcock, C; Chen, W; Axelrod, T; Byun, Y; Coehlo, N K; Cook, K H; Dave, R; de Pater, L; Porrata, R; Kim, D; King, S; Lee, T; Lin, H; Lissauer, J J; Marshall, S L; Protopapas, P; Rice, J A; Schwamb, M E; Wang, S; Wen, C

    2009-11-13

    We present the results of a search for occultation events by objects at distances between 100 and 1000 AU in lightcurves from the Taiwanese-American Occultation Survey (TAOS). We searched for consecutive, shallow flux reductions in the stellar lightcurves obtained by our survey between 7 February 2005 and 31 December 2006 with a total of {approx} 4.5 x 10{sup 9} three-telescope simultaneous photometric measurements. No events were detected, allowing us to set upper limits on the number density as a function of size and distance of objects in Sedna-like orbits, using simple models.

  8. MST3 kinase phosphorylates TAO1/2 to enable Myosin Va function in promoting spine synapse development.

    PubMed

    Ultanir, Sila K; Yadav, Smita; Hertz, Nicholas T; Oses-Prieto, Juan A; Claxton, Suzanne; Burlingame, Alma L; Shokat, Kevan M; Jan, Lily Y; Jan, Yuh-Nung

    2014-12-01

    Mammalian Sterile 20 (Ste20)-like kinase 3 (MST3) is a ubiquitously expressed kinase capable of enhancing axon outgrowth. Whether and how MST3 kinase signaling might regulate development of dendritic filopodia and spine synapses is unknown. Through shRNA-mediated depletion of MST3 and kinase-dead MST3 expression in developing hippocampal cultures, we found that MST3 is necessary for proper filopodia, dendritic spine, and excitatory synapse development. Knockdown of MST3 in layer 2/3 pyramidal neurons via in utero electroporation also reduced spine density in vivo. Using chemical genetics, we discovered thirteen candidate MST3 substrates and identified the phosphorylation sites. Among the identified MST3 substrates, TAO kinases regulate dendritic filopodia and spine development, similar to MST3. Furthermore, using stable isotope labeling by amino acids in culture (SILAC), we show that phosphorylated TAO1/2 associates with Myosin Va and is necessary for its dendritic localization, thus revealing a mechanism for excitatory synapse development in the mammalian CNS. PMID:25456499

  9. Sub-50 nm scratch-proof DLC molds for reversal nanoimprint lithography L. Tao, C. T. Nelson, K. Trivedi, S. Ramachandran, M. Goeckner, L. Overzet, and Walter Hua)

    E-print Network

    Hu, Wenchuang "Walter"

    Sub-50 nm scratch-proof DLC molds for reversal nanoimprint lithography L. Tao, C. T. Nelson, K of the industry is related to the mold life time that significantly affects cost of ownership and manufacturing reproducibility. Nowadays, most often used Si or glass molds that are very expensive can be damaged after certain

  10. Batch Nearest Neighbor Search for Video Retrieval Jie Shao, Zi Huang, Heng Tao Shen, Xiaofang Zhou, Ee-Peng Lim, and Yijun Li

    E-print Network

    Zhou, Xiaofang

    -733654999. Ee-Peng Lim is with Division of Information Systems, School of Com- puter Engineering, Nanyang1 Batch Nearest Neighbor Search for Video Retrieval Jie Shao, Zi Huang, Heng Tao Shen, Xiaofang Zhou, Ee-Peng Lim, and Yijun Li EDICS: 4-KEEP Abstract--To retrieve similar videos to a query clip from

  11. Arsenic Removal from Drinking Water by Adsorptive Media - U.S. EPA Demonstration Project at Taos, NM, Final Performance Evaluation Report

    EPA Science Inventory

    This report documents the activities performed and the results obtained for the EPA arsenic removal technology demonstration project at the Town of Taos in New Mexico. The main objective of the project was to evaluate the effectiveness of Severn Trent Services’ (STS) SORB 33™ ad...

  12. STRESS AND EMOTION CLASSIFICATION USING JITTER AND SHIMMER FEATURES Xi Li', Jidong Tao1, Michael T. Johnson1, Joseph Soltis2, Anne Savage2, Kirsten M. Leong3,

    E-print Network

    Johnson, Michael T.

    for the classification of human speaking styles and of animal vocalization arousal levels. Jitter and shimmer features in classification accuracy for several illustrative datasets, including the SUSAS dataset for human speaking stylesSTRESS AND EMOTION CLASSIFICATION USING JITTER AND SHIMMER FEATURES Xi Li', Jidong Tao1, Michael T

  13. Onset of erosion of a granular bed in a channel driven by fluid flow Anyu Hong, Mingjiang Tao, and Arshad Kudrolli

    E-print Network

    Kudrolli, Arshad

    Onset of erosion of a granular bed in a channel driven by fluid flow Anyu Hong, Mingjiang Tao://scitation.aip.org/content/aip/journal/pof2/27/1?ver=pdfcov Published by the AIP Publishing Articles you may be interested in Erosion); 10.1063/1.4863989 Simulations of granular bed erosion due to laminar shear flow near the critical

  14. Automated classification of single airborne particles from two-dimensional angle-resolved optical scattering (TAOS) patterns by non-linear filtering

    NASA Astrophysics Data System (ADS)

    Crosta, Giovanni Franco; Pan, Yong-Le; Aptowicz, Kevin B.; Casati, Caterina; Pinnick, Ronald G.; Chang, Richard K.; Videen, Gorden W.

    2013-12-01

    Measurement of two-dimensional angle-resolved optical scattering (TAOS) patterns is an attractive technique for detecting and characterizing micron-sized airborne particles. In general, the interpretation of these patterns and the retrieval of the particle refractive index, shape or size alone, are difficult problems. By reformulating the problem in statistical learning terms, a solution is proposed herewith: rather than identifying airborne particles from their scattering patterns, TAOS patterns themselves are classified through a learning machine, where feature extraction interacts with multivariate statistical analysis. Feature extraction relies on spectrum enhancement, which includes the discrete cosine FOURIER transform and non-linear operations. Multivariate statistical analysis includes computation of the principal components and supervised training, based on the maximization of a suitable figure of merit. All algorithms have been combined together to analyze TAOS patterns, organize feature vectors, design classification experiments, carry out supervised training, assign unknown patterns to classes, and fuse information from different training and recognition experiments. The algorithms have been tested on a data set with more than 3000 TAOS patterns. The parameters that control the algorithms at different stages have been allowed to vary within suitable bounds and are optimized to some extent. Classification has been targeted at discriminating aerosolized Bacillus subtilis particles, a simulant of anthrax, from atmospheric aerosol particles and interfering particles, like diesel soot. By assuming that all training and recognition patterns come from the respective reference materials only, the most satisfactory classification result corresponds to 20% false negatives from B. subtilis particles and <11% false positives from all other aerosol particles. The most effective operations have consisted of thresholding TAOS patterns in order to reject defective ones, and forming training sets from three or four pattern classes. The presented automated classification method may be adapted into a real-time operation technique, capable of detecting and characterizing micron-sized airborne particles.

  15. Phase relationships in the BaO-Ga2O3-Ta2O5 system and the structure of Ba6Ga21TaO40.

    PubMed

    Cao, Jiang; Yu, Xiaodi; Kuang, Xiaojun; Su, Qiang

    2012-07-16

    Phase relationships in the BaO-Ga(2)O(3)-Ta(2)O(5) ternary system at 1200 °C were determined. The A(6)B(10)O(30) tetragonal tungsten bronze (TTB) related solution in the BaO-Ta(2)O(5) subsystem dissolved up to ~11 mol % Ga(2)O(3), forming a ternary trapezoid-shaped TTB-related solid solution region defined by the BaTa(2)O(6), Ba(1.1)Ta(5)O(13.6), Ba(1.58)Ga(0.92)Ta(4.08)O(13.16), and Ba(6)GaTa(9)O(30) compositions in the BaO-Ga(2)O(3)-Ta(2)O(5) system. Two ternary phases Ba(6)Ga(21)TaO(40) and eight-layer twinned hexagonal perovskite solid solution Ba(8)Ga(4-x)Ta(4+0.6x)O(24) were confirmed in the BaO-Ga(2)O(3)-Ta(2)O(5) system. Ba(6)Ga(21)TaO(40) crystallized in a monoclinic cell of a = 15.9130(2) Å, b = 11.7309(1) Å, c = 5.13593(6) Å, ? = 107.7893(9)°, and Z = 1 in space group C2/m. The structure of Ba(6)Ga(21)TaO(40) was solved by the charge flipping method, and it represents a three-dimensional (3D) mixed GaO(4) tetrahedral and GaO(6)/TaO(6) octahedral framework, forming mixed 1D 5/6-fold tunnels that accommodate the Ba cations along the c axis. The electrical property of Ba(6)Ga(21)TaO(40) was characterized by using ac impedance spectroscopy. PMID:22734887

  16. The ferroelectricity in perovskite K0.85Ba0.15TaO3+0.075 nanocrystallites

    NASA Astrophysics Data System (ADS)

    Shang, Mingyu; Xu, Chong; Chen, Yan; Ding, Qingfeng; Yuan, Hongming; Sun, Fengyue; Feng, Shouhua

    2015-08-01

    The perovskite K0.85Ba0.15TaO3+0.075 nanocrystallites have been synthesized by mild hydrothermal method for the first time. The powder X-ray diffraction analysis indicates that the crystallographic structure is a primitive cubic, space group Pm-3m with a unit cell edge a=4.00 Å. Heavily Ba doped in K-site was achieved in the perovskite structure with excess oxygen to balance the charge. The chemical substitution changes the crystal structure and electronic structure of KTaO3, which has an impact on its polarization property and induce a ferroelectric phase. The temperature-dependent dielectric response from 300 K to 600 K and hysteresis loop at 300 K provide direct evidence for the ferroelectric character. Its Curie temperature has been obtained from relative dielectric and thermal analysis (TC=460 K).

  17. THE TAOS PROJECT: UPPER BOUNDS ON THE POPULATION OF SMALL KUIPER BELT OBJECTS AND TESTS OF MODELS OF FORMATION AND EVOLUTION OF THE OUTER SOLAR SYSTEM

    SciTech Connect

    Bianco, F. B.; Zhang, Z.-W.; King, S.-K.; Wang, J.-H.; Lee, T.; Lin, H.-C.; Lehner, M. J.; Mondal, S.; Giammarco, J.; Holman, M. J.; Alcock, C.; Coehlo, N. K.; Axelrod, T.; Byun, Y.-I.; Kim, D.-W.; Chen, W. P.; Cook, K. H.; Dave, R.; De Pater, I.; Lissauer, J. J.

    2010-04-15

    We have analyzed the first 3.75 years of data from the Taiwanese American Occultation Survey (TAOS). TAOS monitors bright stars to search for occultations by Kuiper Belt objects (KBOs). This data set comprises 5 x 10{sup 5} star hours of multi-telescope photometric data taken at 4 or 5 Hz. No events consistent with KBO occultations were found in this data set. We compute the number of events expected for the Kuiper Belt formation and evolution models of Pan and Sari, Kenyon and Bromley, Benavidez and Campo Bagatin, and Fraser. A comparison with the upper limits we derive from our data constrains the parameter space of these models. This is the first detailed comparison of models of the KBO size distribution with data from an occultation survey. Our results suggest that the KBO population is composed of objects with low internal strength and that planetary migration played a role in the shaping of the size distribution.

  18. Preliminary geologic map of the Big Costilla Peak area, Taos County, New Mexico, and Costilla County, Colorado

    USGS Publications Warehouse

    Fridrich, Christopher J.; Shroba, Ralph R.; Hudson, Adam M.

    2012-01-01

    This map covers the Big Costilla Peak, New Mex.&nash;Colo. quadrangle and adjacent parts of three other 7.5 minute quadrangles: Amalia, New Mex.–Colo., Latir Peak, New Mex., and Comanche Point, New Mex. The study area is in the southwesternmost part of that segment of the Sangre de Cristo Mountains known as the Culebra Range; the Taos Range segment lies to the southwest of Costilla Creek and its tributary, Comanche Creek. The map area extends over all but the northernmost part of the Big Costilla horst, a late Cenozoic uplift of Proterozoic (1.7-Ga and less than 1.4-Ga) rocks that is largely surrounded by down-faulted middle to late Cenozoic (about 40 Ma to about 1 Ma) rocks exposed at significantly lower elevations. This horst is bounded on the northwest side by the San Pedro horst and Culebra graben, on the northeast and east sides by the Devils Park graben, and on the southwest side by the (about 30 Ma to about 25 Ma) Latir volcanic field. The area of this volcanic field, at the north end of the Taos Range, has undergone significantly greater extension than the area to the north of Costilla Creek. The horsts and grabens discussed above are all peripheral structures on the eastern flank of the San Luis basin, which is the axial part of the (about 26 Ma to present) Rio Grande rift at the latitude of the map. The Raton Basin lies to the east of the Culebra segment of the Sangre de Cristo Mountains. This foreland basin formed during, and is related to, the original uplift of the Sangre de Cristo Mountains which was driven by tectonic contraction of the Laramide (about 70 Ma to about 40 Ma) orogeny. Renewed uplift and structural modification of these mountains has occurred during formation of the Rio Grande rift. Surficial deposits in the study area include alluvial, mass-movement, and glacial deposits of middle Pleistocene to Holocene age.

  19. Preliminary geophysical interpretations of regional subsurface geology near the Questa Mine Tailing Facility and Guadalupe Mountain, Taos County, New Mexico

    USGS Publications Warehouse

    Grauch, V.J.S.; Drenth, Benjamin J.; Thompson, Ren A.; Bauer, Paul W.

    2015-01-01

    This report presents geophysical interpretations of regional subsurface geology in the vicinity of the Tailing Facility of the Questa Mine near Guadalupe Mountain, Taos County, New Mexico, in cooperation with the New Mexico Environment Department. The interpretations were developed from aeromagnetic data, regional gravity data, data from four ground magnetic traverses, geologic mapping, a digital elevation model, and information from a few shallow wells. The resolution of the geophysical data is only appropriate for a broad assessment of the regional setting. Aeromagnetic data provided the most comprehensive information for interpretation. Qualitative and semiquantitative interpretations indicate the nature and extent of volcanic rocks, their relative depths, and inferred contacts between them, as well as conjectured locations of faults. In particular, the aeromagnetic data indicate places where volcanic rocks extend at shallow depths under sedimentary cover. Trachydacites of Guadalupe Mountain are magnetic, but their associated aeromagnetic anomalies are opposite in sign over the northern versus the southern parts of the mountain. The difference indicates that lavas erupted during different magnetic-polarity events in the north (reverse polarity) versus the south (normal polarity) and therefore have different ages. We postulate a buried volcano with reverse-polarity magnetization lies under the northeast side of Guadalupe Mountain, which likely predated the exposed trachydacites. Faults interpreted for the study area generally align with known fault zones. We interpret a northern extension to one of these faults that crosses northwesterly underneath the Tailing Facility. Gravity data indicate that Guadalupe Mountain straddles the western margin of a subbasin of the Rio Grande rift and that significant (>400 meters) thicknesses of both volcanic and sedimentary rocks underlie the mountain.

  20. Conundrums in the legal protection of migrant workers' health rights and relative resolutions: implications from the case of Tseng Hei-tao.

    PubMed

    Liu, Kai

    2013-08-01

    The deteriorating situation of migrant workers' health rights protection was once again highlighted in the case of Tseng Hei-tao. This case explicitly and implicitly showed that four conundrums--the Employment Restriction Conundrum, the Occupational Safety and Health (OSH) Legal Conundrum, the Morality Conundrum and the Identity Conundrum--are barriers to migrant workers' right protection. The health rights of migrant workers could be safeguarded by abolishing the outdated household registration system designed in the planned economy era, improving the rule of law, and strengthening administrative supervisions. This would fundamentally remove these barriers and thus contribute to migrant workers' health rights protection. PMID:23073738

  1. Optical characterization and evaluation of the laser properties of Yb(3+)-doped (La, Sr)(Al, Ta)O(3) single crystals.

    PubMed

    Zhao, Chengchun; Hang, Yin; He, Xiaoming; Zhang, Lianhan; Yin, Jigang; Hu, Pengchao; He, Mingzhu; Ma, En

    2011-03-30

    A Yb(3+)-doped mixed-perovskite single crystal (La, Sr)(Al, Ta)O(3) (LSAT) crystal is grown by the Czochralski method. The absorption spectrum, fluorescence spectrum and fluorescence lifetime of Yb(3+) ions have been investigated, and the spectroscopic parameters of Yb:LSAT have also been calculated. This crystal exhibits a remarkably large ground-state splitting (about 1100 cm(-1)), a relatively long fluorescence lifetime (0.85 ms) and broad absorption and emission bandwidths. The results indicate that the Yb(3+):LSAT crystal is a good candidate for diode-pumped ultrashort and tunable solid-state laser applications. PMID:21378445

  2. Analysis of meteorological data and water chemistry of Latir Lakes, Taos County, New Mexico, 1985-88

    USGS Publications Warehouse

    Anderholm, S.K.; Roybal, R.G.; Risser, D.W.; Somers, Georgene

    1994-01-01

    Data were analyzed to determine the chemistry of atmospheric deposition and water of the Latir Lakes in Taos County New Mexico, from 1985 to 1988. The Latir Lakes consist of a series of nine paternoster lakes that range in altitude from 11,061 to 11,893 feet above sea level. The pH of wet precipitation generally ranged from 4.6 to 5.5 and the specific conductance of wet precipitation ranged from 1 to 18 microsiemens per centimeter at 25 degrees Celsius from December 1985 through September 1988. Snowpack chemistry data indicate a change in the specific conductance, pH, and alkalinity of the snowpack from month to month. The dominant cation in the snowpack is calcium, and the dominant anions are nitrate and sulfate. The samples having the smallest values of specific conductance generally did not contain measurable alkalinity. When the snowpack starts to melt in the spring, specific conductance of the entire snowpack decreases, consistent with the hypothesis that the initial fluid draining from the snowpack transports a large amount of dissolved material out of the snowpack. Water chemistries in the Latir Lakes are similar although specific conductance increases downstream from lake 9 to lake 1. Calcium is the dominant cation and the ions that produce alkalinity are the dominant anions. Concentrations of sodium, magnesium, chloride, and sulfate do not vary substantially from year to year or during the year in a particular lake. Alkalinity and calcium concentration, however, do vary from year to year and during the year. The pH of outflow from the Latir Lakes varies from lake to lake and from year to year. In 1986, the range in pH in the lakes was less than 1 unit in mid-June, but was greater than 2.5 units by late October. The pH generally was larger than 7.0 in all of the lakes and was as large as 9.9 in several of the lakes during the period of study. The pH of outflow water generally increases from early spring to late summer in the Latir Lakes, and snowmelt does not seem to cause the pH to decrease in the lakes. Depth profiles of selected lakes indicate that the dissolved-oxygen concentration approaches zero below the thermocline. This suggests biological oxidation of organic matter in the lower zones in these lakes. Because many organisms cannot live in water containing small dissolved-oxygen concentrations, large volumes of water in lakes 9 and 3 probably are not suitable for habitation during the summer months.

  3. Digital data and derivative products from a high-resolution aeromagnetic survey of the central San Luis basin, covering parts of Alamosa, Conejos, Costilla, and Rio Grande counties, Colorado, and Taos county, New Mexico

    USGS Publications Warehouse

    Bankey, Viki; Grauch, V.J.S.; Webbers, Ank; PRJ, Inc

    2005-01-01

    This report describes data collected from a high-resolution aeromagnetic survey flown over the central San Luis basin during October, 2004, by PRJ, Inc., on contract to the U.S. Geological Survey (USGS). The survey extends from just north of Alamosa, Colorado, southward to just northwest of Taos, New Mexico. It covers large parts of the San Luis Valley in Alamosa, Conejos, Costilla, and Rio Grande Counties, southern Colorado, and the Taos Plateau in Taos County, northern New Mexico. The survey was designed to complement two surveys previously acquired along the eastern borders of the San Luis Basin over the vicinities of Taos, New Mexico (Bankey and others, 2004a) and Blanca, Colorado (Bankey and others, 2004b). Our overall objective in conducting these surveys is to improve knowledge of the subsurface geologic framework in order to understand ground-water systems in populated alluvial basins along the Rio Grande. These USGS efforts are conducted in collaboration with other federal, state, and local governmental entities where possible.

  4. SDI: Solar Dome Instrument for Solar Irradiance Monitoring Tao Liu1, Ankur U. Kamthe1, Varick L. Erickson1, Carlos F. M. Coimbra2 and Alberto E. Cerpa1

    E-print Network

    Cerpa, Alberto E.

    ) weather systems can succeed in es- timating real-time and/or forecasting solar power availabil- itySDI: Solar Dome Instrument for Solar Irradiance Monitoring Tao Liu1, Ankur U. Kamthe1, Varick L data for ground solar irradiance (direct normal and global irradiance) is a major obstacle for the de

  5. Infrared properties of ferropericlase Mg1-xFexO: Experiment and theory Tao Sun,1,* Philip B. Allen,1 David G. Stahnke,2 Steven D. Jacobsen,3 and Christopher C. Homes4

    E-print Network

    Jacobsen, Steven D.

    Sciences, Northwestern University, Evanston, Illinois 60208, USA 4Condensed Matter Physics and Materials of the physical properties elasticity, electronic and vibrational excitations, etc. of fer- ropericlaseInfrared properties of ferropericlase Mg1-xFexO: Experiment and theory Tao Sun,1,* Philip B. Allen

  6. Adler, R. F., H.-Y. M. Yeh, N. Prasad, W.-K. Tao, and J. Simpson, 1991: Microwave simulations of a tropical rainfall system with a three-dimensional cloud model. J.

    E-print Network

    Jiang, Haiyan

    REFERENCES Adler, R. F., H.-Y. M. Yeh, N. Prasad, W.-K. Tao, and J. Simpson, 1991: Microwave simulations of a tropical rainfall system with a three-dimensional cloud model. J. Appl. Meteor., 30, 924­953. Amayenc, P., M. Marzoug, and J. Testud, 1993: Analysis of crossbeam resolution effects in rainfall rate

  7. Amygdalin isolated from Semen Persicae (Tao Ren) extracts induces the expression of follistatin in HepG2 and C2C12 cell lines

    PubMed Central

    2014-01-01

    Background The Chinese medicine formulation ISF-1 (also known as Bu-Yang-Huan-Wu-Tang) for post-stroke rehabilitation could increase the expression of growth-regulating protein follistatin by approximately 4-fold. This study aims to identify the active compounds of ISF-1 for the induction of follistatin expression. Methods Active compounds in ISF-1 responsible for induction of follistatin were identified by a bioactivity-guided fractionation procedure involving liquid-liquid extraction, HPLC separation and RT-PCR detection. The aqueous extracts of seven ISF-1 ingredients including Semen Persicae (Tao Ren) and the S. Persicae-derived fractions were assayed for the induction of follistatin mRNA expression in human hepatocarcinoma HepG2 cells by RT-PCR. The concentrations of isolated compounds were proportionally normalized to the reported IC50 concentration (5.8 mg/mL) of the formulation ISF-1 in HepG2. The active fractions were characterized by reverse-phase HPLC on a C18 column and identified by mass spectrometry. Results Three ingredients of ISF-1, namely S. Persicae (Tao Ren), Pheretima (Di Long), and Flos Carthami (Hong Hua), induced the expression of follistatin mRNA. Among these, the ingredient S. Persicae were the most active, and amygdalin from S. Persicae extract was identified as a novel follistatin inducer. Amygdalin stimulated the growth of skeletal muscle cell line C2C12 cells in a concentration-dependent manner. Conclusions Amygdalin isolated from S. Persicae extract in ISF-1 through a bioactivity-guided fractionation procedure induced the expression of follistatin in HepG2 and C2C12 cell lines. PMID:25237385

  8. Preparation and ductile-to-brittle transition temperature of the La-TZM alloy Ping Hu, Fan Yang, Kuai-She Wang, Zhi-tao Yu, Jiang-fei Tan, Rui

    E-print Network

    Volinsky, Alex A.

    Ping Hu, Fan Yang, Kuai-She Wang, Zhi-tao Yu, Jiang-fei Tan, Rui Song, Bo-liang Hu, Hua Wang, Huan November 2014 Revised date: 17 March 2015 Accepted date: 1 May 2015 Please cite this article as: Hu Ping and ductile-to-brittle transition temperature of the La-TZM alloy plates Ping Hu 1* , Fan Yang 1 , Kuai

  9. Proteomic Identification of Nrf2-Mediated Phase II Enzymes Critical for Protection of Tao Hong Si Wu Decoction against Oxygen Glucose Deprivation Injury in PC12 Cells

    PubMed Central

    Qi, Hong-yi; Li, Li; Yu, Jie; Chen, Lu; Huang, Yong-liang; Ning, Ling; Jiang, Zhuyun; Yang, Na; Xu, Xiao-yu

    2014-01-01

    Chinese herbal medicine formula Tao Hong Si Wu decoction (THSWD) is traditionally used in China for cerebrovascular diseases. However, the molecular mechanisms of THSWD associated with the cerebral ischemia reperfusion injury are largely unknown. The current study applied the two-dimensional gel electrophoresis-based proteomics to investigate the different protein profiles in PC12 cells with and without the treatment of THSWD. Twenty-six proteins affected by THSWD were identified by MALDI-TOF mass spectrometry. Gene ontology analysis showed that those proteins participated in several important biological processes and exhibited diverse molecular functions. In particular, six of them were found to be phase II antioxidant enzymes, which were regulated by NF-E2-related factor-2 (Nrf2). Quantitative PCR further confirmed a dose-dependent induction of the six phase II enzymes by THSWD at the transcription level. Moreover, the individual ingredients of THSWD were discovered to synergistically contribute to the induction of phase II enzymes. Importantly, THSWD's protection against oxygen-glucose deprivation-reperfusion (OGD-Rep) induced cell death was significantly attenuated by antioxidant response element (ARE) decoy oligonucleotides, suggesting the protection of THSWD may be likely regulated at least in part by Nrf2-mediated phase II enzymes. Thus, our data will help to elucidate the molecular mechanisms underlying the neuroprotective effect of THSWD. PMID:24949080

  10. Regional vegetation dynamics and its response to climate change—a case study in the Tao River Basin in Northwestern China

    NASA Astrophysics Data System (ADS)

    Li, Changbin; Qi, Jiaguo; Yang, Linshan; Wang, Shuaibing; Yang, Wenjin; Zhu, Gaofeng; Zou, Songbing; Zhang, Feng

    2014-12-01

    The 30-year normalized-difference vegetation index (NDVI) time series from AVHRR/MODIS satellite sensors was used in this study to assess the regional vegetation dynamic changes in the Tao River Basin, which cuts across the Eastern Tibetan Plateau (ETP) and the Southwestern Loess Plateau (SLP). First, principal component and correlation analyses were carried out to determine the key climatic variables driving ecological change in the region. Then, regression models were tested to correlate NDVI with the selected climatic variables to determine their predictive power. Finally, Sen’s slope method was used to determine how terrestrial vegetation has responded to regional climate change in the region. The results indicated an average winter season NDVI value of 0.14 in the ETP but only 0.04 in the SLP. Primarily driven by increasing temperature, vegetation growth has generally been enhanced since 1981; spring NDVI increased by 0.03 every 10 years in the ETP and 0.02 in the SLP. Further, results from trend analyses suggest vegetation growth in the ETP shifted to earlier-start and earlier-end dates, however in the SLP, the growing season has been extended with an earlier-start and later-end date. The precipitation threshold for vegetation germination, measured by the cumulative spring rainfall, was found to be 44 mm for both the ETP and SLP.

  11. Massively Parallel Assimilation of TOGA/TAO and Topex/Poseidon Measurements into a Quasi Isopycnal Ocean General Circulation Model Using an Ensemble Kalman Filter

    NASA Technical Reports Server (NTRS)

    Keppenne, Christian L.; Rienecker, Michele; Borovikov, Anna Y.; Suarez, Max

    1999-01-01

    A massively parallel ensemble Kalman filter (EnKF)is used to assimilate temperature data from the TOGA/TAO array and altimetry from TOPEX/POSEIDON into a Pacific basin version of the NASA Seasonal to Interannual Prediction Project (NSIPP)ls quasi-isopycnal ocean general circulation model. The EnKF is an approximate Kalman filter in which the error-covariance propagation step is modeled by the integration of multiple instances of a numerical model. An estimate of the true error covariances is then inferred from the distribution of the ensemble of model state vectors. This inplementation of the filter takes advantage of the inherent parallelism in the EnKF algorithm by running all the model instances concurrently. The Kalman filter update step also occurs in parallel by having each processor process the observations that occur in the region of physical space for which it is responsible. The massively parallel data assimilation system is validated by withholding some of the data and then quantifying the extent to which the withheld information can be inferred from the assimilation of the remaining data. The distributions of the forecast and analysis error covariances predicted by the ENKF are also examined.

  12. Validating satellite altimeter measurements of internal tides with long-term TAO/TRITON buoy observations at 2°S-156°E

    NASA Astrophysics Data System (ADS)

    Zhou, Xiao-Hui; Wang, Dong-Ping; Chen, Dake

    2015-05-01

    Satellite altimetry is regularly used to map the global distribution of mode-1 internal tides. Validating altimeter measurements of internal tides with in situ data is difficult as the mooring observations typically are too short compared with the altimetry. Here taking advantage of the long-term (since 1999) Tropical Atmosphere-Ocean/Triangle Trans-Ocean Buoy Network (TAO/TRITON) buoy observations at 2°S-156°E located at a TOPEX/Poseidon crossover in a region of strong internal tides, direct comparisons are made between altimeter and in situ measurements over a common 15 year period. The hourly buoy data are decimated every 9.9 day to emulate altimeter measurements. The altimeter and decimated buoy data are highly coherent at the aliased semidiurnal period (~60 day), and they agree well for the stationary semidiurnal internal tide. For the nonstationary internal tide, which consists of a significant annual cycle, the demodulated amplitude from the altimeter appears to be contaminated by nontidal signals. The demodulated amplitude from the decimated buoy data, on the other hand, is capable of resolving the temporal variability. This suggests the potential of mapping nonstationary internal tides from satellites.

  13. Structures and magnetic properties of new fluorite-related quaternary rare earth oxides LnY2TaO7 and LaLn2RuO7 (Ln=rare earths)

    NASA Astrophysics Data System (ADS)

    Hinatsu, Yukio; Doi, Yoshihiro

    2016-01-01

    New fluorite-related quaternary rare earth oxides LnY2TaO7 (Ln=La-Dy) and LaLn2RuO7 (Ln=Eu-Tb) have been prepared. They crystallize in an orthorhombic superstructure of cubic fluorite with space groups C2221 and Cmcm, respectively. The results of the Rietveld analysis for LnY2TaO7 (Ln=La-Dy) indicate that there exists no structural ordering of the Ln and Y ions at the eight-coordinate 4b site and the seven-coordinate 8c site, but the larger Ln ions occupy the eight-coordinate 4b site rather than the seven-coordinate 8c site, with increasing the Ln ionic radius. On the other hand, the results of the Rietveld analysis for the X-ray diffraction profiles of LaTb2RuO7 showed that La and Tb atoms are almost situated at the eight-coordinated site (4a site) and seven-coordinated site (8g site), respectively, i.e., cation ordering occurs on the 4a and 8g sites. All compounds LnY2TaO7 (Ln=La-Dy) are paramagnetic down to 1.8 K. On the other hand, LaTb2RuO7 shows an antiferromagnetic transition at 17 K. In addition, another magnetic anomaly has been found at 10 K. Analysis of the magnetic specific heat for LaTb2RuO7 indicates that the magnetic transitions at 10 and 17 K are due to the magnetic ordering of Tb3+ and Ru5+ ions, respectively.

  14. Regional Vegetation Dynamics and Its Response to Climate Change—A Case Study in the Tao River Basin in Northwestern China

    NASA Astrophysics Data System (ADS)

    Qi, J.; Li, C.

    2014-12-01

    Stretching across the eastern Tibetan Plateau and the southwestern Loess Plateau, the Tao River Basin (TRB) is an ideal ecosystem to study eco-hydrological processes in a contiguous landscape but climatically different schemes. In this study, we used the normalized-difference vegetation index (NDVI) data, derived from AVHRR/MODIS satellite sensors, to quantify the regional vegetation dynamic changes in the TRB and determine the key climatic factors driving these changes in the past 30 years through principal component and correlation analyses. We then developed regression models to predict NDVI changes as a function of the climatic factors. Using Sen's slope trend analysis of the climatic data and the regression models we examined how terrestrial vegetation has responded to regional climate change in the TRB. The regression results showed the average winter base NDVI values of 0.14 and 0.04 in the eastern Tibetan Plateau and the southwestern Loess Plateau, respectively. Primarily driven by increasing temperature, the vegetation growth has generally been enhanced since 1981; the spring NDVI increased by 0.03 every 10 years in the eastern Tibetan Plateau, and 0.02/10 years in the southwestern Loess Plateau. The Sen's slope trend analyses showed that the vegetation growing season in the eastern Tibetan Plateau shifted to an earlier start and earlier end, but in contrast the southwestern Loess Plateau experienced an earlier start but later end. The precipitation threshold for vegetation germination is a cumulative spring rainfall of 44 mm; less than this precipitation indicates a spring drought and less vegetation growth.

  15. Gallium-67 uptake by the thyroid associated with progressive systemic sclerosis

    SciTech Connect

    Sjoberg, R.J.; Blue, P.W.; Kidd, G.S.

    1989-01-01

    Although thyroidal uptake of gallium-67 has been described in several thyroid disorders, gallium-67 scanning is not commonly used in the evaluation of thyroid disease. Thyroidal gallium-67 uptake has been reported to occur frequently with subacute thyroiditis, anaplastic thyroid carcinoma, and thyroid lymphoma, and occasionally with Hashimoto's thyroiditis and follicular thyroid carcinoma. A patient is described with progressive systemic sclerosis who, while being scanned for possible active pulmonary involvement, was found incidentally to have abnormal gallium-67 uptake only in the thyroid gland. Fine needle aspiration cytology of the thyroid revealed Hashimoto's thyroiditis. Although Hashimoto's thyroiditis occurs with increased frequency in patients with progressive systemic sclerosis, thyroidal uptake of gallium-67 associated with progressive systemic sclerosis has not, to our knowledge, been previously described. Since aggressive thyroid malignancies frequently are imaged by gallium-67 scintigraphy, fine needle aspiration cytology of the thyroid often is essential in the evaluation of thyroidal gallium-67 uptake.

  16. Reconstruction of the 1997/1998 El Nino from TOPEX/POSEIDON and TOGA/TAO Data Using a Massively Parallel Pacific-Ocean Model and Ensemble Kalman Filter

    NASA Technical Reports Server (NTRS)

    Keppenne, C. L.; Rienecker, M.; Borovikov, A. Y.

    1999-01-01

    Two massively parallel data assimilation systems in which the model forecast-error covariances are estimated from the distribution of an ensemble of model integrations are applied to the assimilation of 97-98 TOPEX/POSEIDON altimetry and TOGA/TAO temperature data into a Pacific basin version the NASA Seasonal to Interannual Prediction Project (NSIPP)ls quasi-isopycnal ocean general circulation model. in the first system, ensemble of model runs forced by an ensemble of atmospheric model simulations is used to calculate asymptotic error statistics. The data assimilation then occurs in the reduced phase space spanned by the corresponding leading empirical orthogonal functions. The second system is an ensemble Kalman filter in which new error statistics are computed during each assimilation cycle from the time-dependent ensemble distribution. The data assimilation experiments are conducted on NSIPP's 512-processor CRAY T3E. The two data assimilation systems are validated by withholding part of the data and quantifying the extent to which the withheld information can be inferred from the assimilation of the remaining data. The pros and cons of each system are discussed.

  17. Re-examination of siRNA specificity questions role of PICH and Tao1 in the spindle checkpoint and identifies Mad2 as a sensitive target for small RNAs.

    PubMed

    Hübner, Nadja C; Wang, Lily Hui-Ching; Kaulich, Manuel; Descombes, Patrick; Poser, Ina; Nigg, Erich A

    2010-04-01

    The DNA-dependent adenosine triphosphatase (ATPase) Plk1-interacting checkpoint helicase (PICH) has recently been implicated in spindle checkpoint (SAC) signaling (Baumann et al., Cell 128(1):101-114, 2007). Depletion of PICH by siRNA abolished the SAC and resulted in an apparently selective loss of Mad2 from kinetochores, suggesting a role for PICH in the regulation of the Mad1-Mad2 interaction. An apparent rescue of SAC functionality by overexpression of PICH in PICH-depleted cells initially seemed to confirm a role for PICH in the SAC. However, we have subsequently discovered that all PICH-directed siRNA oligonucleotides that abolish the SAC also reduce Mad2 mRNA and protein expression. This reduction is functionally significant, as PICH siRNA does not abolish SAC activity in a cell line that harbors a bacterial artificial chromosome driving the expression of murine Mad2. Moreover, we identified several siRNA duplexes that effectively deplete PICH but do not significantly affect SAC functionality or Mad2 abundance or localization. Finally, we discovered that the ability of overexpressed PICH to restore SAC activity in PICH-depleted cells depends on sequestration of the mitotic kinase Plk1 rather than ATPase activity of PICH, pointing to an underlying mechanism of "bypass suppression." In support of this view, depletion or inhibition of Plk1 also rescued SAC activity in cells harboring low levels of Mad2. This observation suggests that a reduction of Plk1 activity partially compensates for reduced Mad2 levels and argues that Plk1 normally reduces the strength of SAC signaling. Collectively, our results question the role of PICH in the SAC and instead identify Mad2 as a sensitive off target for small RNA duplexes. In support of the latter conclusion, our evidence suggests that an off-target effect on Mad2 may also contribute to explain the apparent role of the Tao1 kinase in SAC signaling. PMID:19904549

  18. Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement

    PubMed Central

    Bianco, Antonio C.; Bauer, Andrew J.; Burman, Kenneth D.; Cappola, Anne R.; Celi, Francesco S.; Cooper, David S.; Kim, Brian W.; Peeters, Robin P.; Rosenthal, M. Sara; Sawka, Anna M.

    2014-01-01

    Background: A number of recent advances in our understanding of thyroid physiology may shed light on why some patients feel unwell while taking levothyroxine monotherapy. The purpose of this task force was to review the goals of levothyroxine therapy, the optimal prescription of conventional levothyroxine therapy, the sources of dissatisfaction with levothyroxine therapy, the evidence on treatment alternatives, and the relevant knowledge gaps. We wished to determine whether there are sufficient new data generated by well-designed studies to provide reason to pursue such therapies and change the current standard of care. This document is intended to inform clinical decision-making on thyroid hormone replacement therapy; it is not a replacement for individualized clinical judgment. Methods: Task force members identified 24 questions relevant to the treatment of hypothyroidism. The clinical literature relating to each question was then reviewed. Clinical reviews were supplemented, when relevant, with related mechanistic and bench research literature reviews, performed by our team of translational scientists. Ethics reviews were provided, when relevant, by a bioethicist. The responses to questions were formatted, when possible, in the form of a formal clinical recommendation statement. When responses were not suitable for a formal clinical recommendation, a summary response statement without a formal clinical recommendation was developed. For clinical recommendations, the supporting evidence was appraised, and the strength of each clinical recommendation was assessed, using the American College of Physicians system. The final document was organized so that each topic is introduced with a question, followed by a formal clinical recommendation. Stakeholder input was received at a national meeting, with some subsequent refinement of the clinical questions addressed in the document. Consensus was achieved for all recommendations by the task force. Results: We reviewed the following therapeutic categories: (i) levothyroxine therapy, (ii) non–levothyroxine-based thyroid hormone therapies, and (iii) use of thyroid hormone analogs. The second category included thyroid extracts, synthetic combination therapy, triiodothyronine therapy, and compounded thyroid hormones. Conclusions: We concluded that levothyroxine should remain the standard of care for treating hypothyroidism. We found no consistently strong evidence for the superiority of alternative preparations (e.g., levothyroxine–liothyronine combination therapy, or thyroid extract therapy, or others) over monotherapy with levothyroxine, in improving health outcomes. Some examples of future research needs include the development of superior biomarkers of euthyroidism to supplement thyrotropin measurements, mechanistic research on serum triiodothyronine levels (including effects of age and disease status, relationship with tissue concentrations, as well as potential therapeutic targeting), and long-term outcome clinical trials testing combination therapy or thyroid extracts (including subgroup effects). Additional research is also needed to develop thyroid hormone analogs with a favorable benefit to risk profile. PMID:25266247

  19. The Tao of Teaching: Romance and Process.

    ERIC Educational Resources Information Center

    Schindler, Stefan

    1991-01-01

    Because college teaching aims to elevate, not entertain, it must be nourished and appreciated as a pedagogical alchemy mixing facts and feelings, ideas and skills, history and mystery. The current debate on educational reform should focus more on quality of learning experience, and on how to create and sustain it. (MSE)

  20. The Tao of It and Bit

    E-print Network

    Ovidiu Cristinel Stoica

    2015-08-24

    The main mystery of quantum mechanics is contained in Wheeler's delayed choice experiment, which shows that the past is determined by our choice of what quantum property to observe. This gives the observer a participatory role in deciding the past history of the universe. Wheeler extended this participatory role to the emergence of the physical laws ("law without law"). Since what we know about the universe comes in yes/no answers to our interrogations, this led him to the idea of "it from bit" (which includes the participatory role of the observer as a key component). The yes/no answers to our observations ("bit") should always be compatible with the existence of at least a possible reality - a global solution ("it") of the Schrodinger equation. I argue that there is in fact an interplay between "it" and "bit". The requirement of global consistency leads to apparently acausal and nonlocal behavior, explaining the weirdness of quantum phenomena. As an interpretation of Wheeler's "it from bit" and "law without law", I discuss the possibility that the universe is mathematical, and that there is a "mother of all possible worlds" - named the "Axiom Zero".

  1. 75 FR 81437 - Amendment of Class E Airspace; Taos, NM

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-28

    ... (75 FR 66345) Docket No. FAA-2010-0842. Interested parties were invited to participate in this... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does... continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565,...

  2. Tao Rising: Sexism and Feminist/Transpersonal Therapy.

    ERIC Educational Resources Information Center

    Sawyer, Llewlee L.

    This report presents a dialectical model of identity development which is based on observations of how the self evolves within the context of feminist/transpersonal therapy. Developmental stages which are identified include fusion (Stage I), differentiation (Stage II), and integration (Stage III) of the Child (asserting) and Parent (nurturing)…

  3. Research EthicsResearch Ethics T XiTao Xie

    E-print Network

    Xie, Tao

    conference date; need check Editor-in-Chief 3 #12;Plagiarism and Self-PlagiarismPlagiarism and Self Plagiarism htt // / bli ti / li i / l i i· http://www.acm.org/publications/policies/plagiarism_p olicy http // ieee org/ eb/p blications/rights/Plagiarism· http://www.ieee.org/web/publications/rights/Plagiarism

  4. Fei Tao and Carlos Busso Multimodal Signal Processing (MSP) Laboratory

    E-print Network

    Busso, Carlos

    is a feasible alternative to improve the performance of whisper speech recognition. Future Directions §Fuse §40 Speakers (20 male, 20 female) §Isolated digits, read sentence and spontaneous §Recorded states) §Conditions (leave-one-out cross validation) §Speaker independent (SI) §Speaker dependent (SD

  5. Cell Biology Modeling Development and Yong-Tao Zhang2

    E-print Network

    Zhang, Yong-Tao

    differently at different locations in space (Wolpert 1969). (See Figure 1.1 for an illustration). In all multicellular animals, this process is orchestrated by morphogens, molecules that are produced at discrete sites at tissue scale: different color of cells repre- senting different fate of the cell. applied to studying

  6. Compressive Sensing Based on Candes and Tao's work

    E-print Network

    Vaswani, Namrata

    DCT coefficients are zero (or small enough to be approx. by zero): exploited by JPEG. #12;Idea of CS Uncertainty Principle (UUP) at about level 3S", then the solution, ^x to P1 is unique and is equal to x(e-N )) · Similar results exist for random Fourier and Bernoulli also. #12;Uniform Uncertainty Principle

  7. The Tao of CHI: Towards Effective Human-Computer Interaction

    E-print Network

    Media Laboratory, GmbH Schloss-Wolfsbrunnenweg 33 D-69118 Heidelberg, Germany robert- tween the user and the system increased recognition and understanding accuracies to a level that systems in Walker et al. (2000) . The work described herein consti- tutes a starting point for a scientific

  8. 6d SCFTs, 5d Dualities and Tao Web Diagrams

    E-print Network

    Hirotaka Hayashi; Sung-Soo Kim; Kimyeong Lee; Futoshi Yagi

    2015-09-10

    We propose 5d descriptions of 6d ${\\cal N}=(1,0)$ superconformal field theories arising from Type IIA brane configurations with an $O8^-$-plane. We T-dualize the brane diagram along a compactification circle and obtain a 5-brane web diagram with two $O7^-$-planes. The gauge theory description of the resulting 5d theory for a given 6d superconformal field theory is not unique, and we argue that the non-uniqueness leads to various dual 5d gauge theories. There are three sources which lead to the 5d dualities. One type comes from either resolving both or one of the two $O7^-$-planes. The two situations give us two different ways to read off a 5d gauge theory from essentially the same web diagram. The second type originates from different distributions of D5 or D7-branes, shifting the gauge group ranks of the 5d quiver theory. The last one comes from the 90 or 45 degree rotations of the 5-brane web diagram, which is a part of the $SL(2,\\mathbb{Z})$ duality of Type IIB string theory, leading to completely different group structure. These lead to a very rich class of dualities between 5d gauge theories whose UV completion is the same 6d superconformal field theory. We also explore Higgsing of the 6d theories and their 5d counterparts. Decoupling the same flavors from the dual 5d theories gives rise to another dual 5d theories whose UV completion is the same 5d superconformal field theory. Finally we propose the 6d description of 5d theories which is obtained by a generalization of 5d $T_N$ theories with additional flavors, which turns out not to be in the class of Type IIA brane construction generically.

  9. 77 FR 36994 - Questa Ranger District, Carson National Forest; Taos County, NM; Taos Ski Valley's 2010 Master...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-20

    ...intent was published in the Federal Register on September 29, 2011 (76 FR 60451) modifying the proposed action to relocate the snow tubing area and add the relocation of an existing footbridge across the Rio Hondo. The Environmental Protection Agency...

  10. 75 FR 71414 - Questa Ranger District, Carson National Forest; Taos County, NM; Taos Ski Valley's 2010 Master...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-23

    ...would be reconfigured to allow the Bison lot to become a thoroughfare. --Constructing an extra parking bay north of the Armadillo lot. The reconfiguration and extra parking bay would have no net gain or loss of day parking. --Replacing Lifts 4,...

  11. Winter SkiingTaos Ski Valley, Taos, NM 4:45am Meet at the Outdoor Adventure Center

    E-print Network

    Aazhang, Behnaam

    Gear: Money for 4-5 meals on road (ROPE covers all cabin/camp meals) Warm comfortable clothing to purchase may be available at low cost from mail order suppliers or your local outdoor specialty shop. Our. If you are unsure whether an item or clothing you own is appropriate for this trip, please contact us

  12. 76 FR 60451 - Questa Ranger District, Carson National Forest; Taos County, NM; Taos Ski Valley's 2010 Master...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-29

    ... (75 FR 71414-71415, November 23, 2010) to prepare an environmental impact statement for a proposal to... develop the snowtubing trails where Chair 3 (Beginner Lift) and Strawberry Hill are currently located....

  13. 77 FR 36994 - Questa Ranger District, Carson National Forest; Taos County, NM; Taos Ski Valley's 2010 Master...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-20

    ... Intent (75 FR 71414-71415, November 23, 2010) to prepare an environmental impact statement for a proposal... corrected notice of intent was published in the Federal Register on September 29, 2011 (76 FR 60451... (NOA) for the draft EIS in the Federal Register on January 13, 2012 (77 FR 2060). Revised Dates:...

  14. 76 FR 60451 - Questa Ranger District, Carson National Forest; Taos County, NM; Taos Ski Valley's 2010 Master...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-29

    ...Service has modified the proposed action and proposes to develop the snowtubing trails where Chair 3 (Beginner Lift) and Strawberry Hill are currently located. The modified proposed action would: (1) Reduce the potential impacts to wildlife habitat...

  15. Localization of the human 64kD autoantigen D1 to myofibrils in a subset of extraocular muscle fibers

    NASA Technical Reports Server (NTRS)

    Conley, C. A.; Fowler, V. M.

    1999-01-01

    PURPOSE. To evaluate the tissue-specific expression pattern of the 64kD human autoantigen D1, a tropomodulin-related protein that may be involved in thyroid-associated ophthalmopathy. METHODS. Recombinant 64kD human autoantigen D1 was generated in a bacterial expression system and used to immunize rabbits. Specific antibodies were affinity-purified and used for Western blots on normal and hyperthyroid rat and rabbit tissue, and immunofluorescence localization on cryosections of rat tissue. RESULTS. Anti-64kD human autoantigen D1 antibodies recognize specifically a approximately 70kD polypeptide in western blots of extraocular muscle, sternothyroid muscle, and smooth muscle. Immunofluorescence staining demonstrates that the 64kD human autoantigen D1 localizes to myofibrils in slow fibers from rat extraocular and sternothyroid muscle. The level of this protein is not altered in extraocular muscles from hyperthyroid rabbits. CONCLUSIONS. The 64kD human autoantigen D1 is expressed in slow fibers of extraocular and sternothyroid muscles as a component of myofibrils, and is not upregulated in conditions of hyperthyroidism.

  16. Energy-efficient Polling Protocols in RFID Systems Yan Qiao, Shigang Chen, Tao Li

    E-print Network

    Chen, Shigang

    ,tali}@cise.ufl.edu Shiping Chen Network Information Center University of Shanghai for Science & Technology, Shanghai, China. Battery-powered active tags are likely to gain more popularity due to their long operational ranges in large scale, a much better choice is to use battery-powered active tags because of their long

  17. SALIENT MOTION DETECTION IN CROWDED SCENES Chen Change Loy, Tao Xiang, Shaogang Gong

    E-print Network

    Gong, Shaogang

    , Queen Mary University of London ABSTRACT To reduce cognitive overload in CCTV monitoring, it is crit detection, counter flow detection, and unstable crowd flow detection. 1. INTRODUCTION The attention of CCTV

  18. Video Behavior Profiling for Anomaly Detection Tao Xiang, Member, IEEE, and Shaogang Gong

    E-print Network

    Gong, Shaogang

    quantities of surveillance video data generated continuously by closed-circuit television (CCTV) systems. One detection. Given a 24/7 continuously recorded video or an online CCTV input, the goal of automatic behavior

  19. Learning Rare Behaviours Jian Li, Timothy M Hospedales, Shaogang Gong, Tao Xiang

    E-print Network

    Gong, Shaogang

    . Extensive validation using both simulated and real-world CCTV video data demonstrates the superior). additional information about any rare behaviours. For example, whilst the ma- jority of daily CCTV recordings

  20. Security and Surveillance Shaogang Gong and Chen Change Loy and Tao Xiang

    E-print Network

    Gong, Shaogang

    Introduction There has been an accelerated expansion of Closed-Circuit TeleVision (CCTV) surveillance in recent operators eyeballing CCTV screens. Miss-detections could be caused by (1) excessive number of video screens

  1. Materials Data on TaO2F (SG:131) by Materials Project

    DOE Data Explorer

    Kristin Persson

    2014-11-02

    Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations

  2. Self-adaptive Cloud Capacity Planning Yexi Jiang, Chang-shing Perng, Tao Li, Rong Chang

    E-print Network

    Li, Tao

    an integrated system with intelligent cloud capacity prediction. Considering the unique characteristics] bring new challenges to IT infrastructure capacity management. As cloud computing promises pay. For the cloud providers, hardware resources still require long acquisition and deployment process. If the actual

  3. ORIGINAL ARTICLE Xueyuan Cao Kejian Li Sang-Gon Suh Tao Guo

    E-print Network

    Becraft, Philip W.

    .) CRINKLY4 (CR4) gene encodes a serine/threonine receptor-like kinase that controls an array redundant function. Keywords Arabidopsis Æ CRINKLY4 Æ Evolution Oryza Æ Receptor-like kinase Æ Signal-Glucuronidase Æ RCC1: Regulator of chromosome condensation 1 Æ RLK: Receptor-like kinase Æ SAM: Shoot apical

  4. doi: 10.3319/TAO.2013.03.11.01(TT) * Corresponding author

    E-print Network

    Lin, Andrew Tien-Shun

    2013 AbSTrAcT A compressed fossil seed, described as Carpolithes sp., is found in the coal. Ocean. Sci., Vol. 24, No. 4, Part II, 731-735, August 2013 Fossil Seed from the Miocene Shihti Formation from the Formation are reported for the first time. Key words: Carpolithes, Fossil seed, Testa, Miocene

  5. Multi-Camera Activity Correlation Analysis Chen Change Loy, Tao Xiang and Shaogang Gong

    E-print Network

    Gong, Shaogang

    -camera activity analysis methods [6, 12, Figure 1. Three consecutive frames from a typical public space CCTV video, both assumptions are largely invalid for activities captured by CCTV cameras in public spaces typ

  6. A VARIATION NORM CARLESON THEOREM RICHARD OBERLIN ANDREAS SEEGER TERENCE TAO

    E-print Network

    Seeger, Andreas

    for the Fourier series, (1) Snf(x) S[f](n, x) = n k=-n fk e2ikx ; here n N0 = {0, 1, 2, . . . }. The celebrated theorem by Carleson [4] states that if f is square integrable then Snf converges to f almost everywhere |Snf| Lp(T) C f Lp(T) for all f Lp(T); see also [10], [20], and [12] for other proofs of this fact

  7. Cryo-Electron-Microscopy Reconstruction of Partially Symmetric Objects Michael G. Rossmann1 and Yizhi Tao

    E-print Network

    Tao, Yizhi Jane

    Cryo-Electron-Microscopy Reconstruction of Partially Symmetric Objects Michael G. Rossmann1. 1999 Academic Press Key Words: electron microscopy; image reconstruc- tion; noncrystallographic the advent of cryo-electron microscopy (cryo- EM). A vast amount of information has been gath- ered

  8. Stream-based Active Unusual Event Detection Chen Change Loy, Tao Xiang and Shaogang Gong

    E-print Network

    Gong, Shaogang

    strategies in identifying unusual events. In addition, better performance is achieved by using adaptive multi-criteria approach compared to existing single criterion and multi-criteria active learning strategies. 1 as a stream-based solution, i.e. it makes decision on-the-fly on whether to query for labels. It adaptively

  9. doi: 10.3319/TAO.2011.09.23.02(T) * Corresponding author

    E-print Network

    Wu, Yih-Min

    hazard evaluation and suggests the re-evaluation of a seismic hazard immediately after a large earthquake 2010 Darfield earthquake. Results show an increase of seismic hazards due to the stress increase a low seismic hazard. Surprisingly, the M 7.1, 4 September 2010 Darfield earthquake, 40 km west

  10. A robust reconstruction for unstructured WENO and Yong-Tao Zhang3

    E-print Network

    Zhang, Yong-Tao

    equations (PDEs). While WENO schemes on structured meshes are quite mature, the development of finite volume and accuracy of the scheme. Key Words: Weighted essentially non-oscillatory (WENO) schemes, finite volume volume version. In [12], third and fifth order finite differ- ence WENO schemes in multi-space dimensions

  11. ProvenanceLens: Service Provenance Management in the Cloud Tao Li1,2,3

    E-print Network

    Liu, Ling

    , analyze causes of service failures, detect security vulnerabilites. Both Internet company (such as google, twitter) and software company pay more attention to service behavior monitoring [1,2], because service of services involved in accomplishing a job also continues to increase. This raises more challenges

  12. Materials Data on Na3Ca2TaO6 (SG:70) by Materials Project

    DOE Data Explorer

    Kristin Persson

    2014-11-02

    Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations

  13. Geologic map of the Sunshine 7.5' quadrangle, Taos County, New Mexico

    USGS Publications Warehouse

    Thompson, Ren A.; Turner, Kenzie J.; Shroba, Ralph R.; Cosca, Michael A.; Ruleman, Chester A.; Lee, John P.; Brandt, Theodore R.

    2014-01-01

    Pliocene and younger basin deposition was accommodated along predominantly north-trending fault-bounded grabens and is preserved as poorly exposed fault scarps that cut lava flows of Ute Mountain volcano, north of the map area. The Servilleta Basalt and younger surficial deposits record largely down-to-east basinward displacement. Faults are identified with varying confidence levels in the map area. Recognizing and mapping faults developed near the surface in relatively young, brittle volcanic rocks is difficult because: (1) they tend to form fractured zones tens of meters wide rather than discrete fault planes, (2) the relative youth of the deposits has resulted in only modest displacements on most faults, and (3) some of the faults may have significant strike-slip components that do not result in large vertical offsets that are readily apparent in offset of sub-horizontal contacts. Those faults characterized as “certain” either have distinct offset of map units or had slip planes that were directly observed in the field. Lineaments defined from magnetic anomalies form an additional constraint on potential fault locations.

  14. doi: 10.3319/TAO.2013.01.22.01(T) * Corresponding author

    E-print Network

    Wu, Yih-Min

    January 2013 AbSTrACT Using seismic activity and the Meishan earthquake sequence that occurred from 1904 is assessed. The long-term earthquake occurrence rate in Taiwan was evaluated using a smoothing kernel. The highest seismicity rate was calculated around the Chiayi region. To consider earthquake interactions

  15. TAO ET AL. VOL. 6 ' NO. 3 ' 23192325 ' 2012 www.acsnano.org

    E-print Network

    - taxial growth of graphene on single crystal Cu (111), but with a large defect-peak and small domains to hydro- carbon gas to facilitate low-defect mono- layer graphene growth on copper foils owing at temperatures growth window using a hydrogen-free methane precursor for low-defects, and electron

  16. doi: 10.3319/TAO.2012.02.29.01(TT) * Corresponding author

    E-print Network

    Lee, Jian-Cheng

    of Southernmost Longitudinal Valley in Eastern Taiwan: A Joint Analysis of Leveling and GPS Measurements Horng a detailed vertical velocity field in southernmost Longitudinal Valley where shows a complex three- fault of 30 mm yr-1 occurs at the hanging wall of the Lichi fault on the western Coastal Range. However

  17. Effects of Vertical Wind Shear on the Predictability of Tropical Cyclones FUQING ZHANG AND DANDAN TAO

    E-print Network

    Thompson, Anne

    Effects of Vertical Wind Shear on the Predictability of Tropical Cyclones FUQING ZHANG AND DANDAN methods. A recent study by Zhang et al. (2011) showed that the hurricane intensity forecast ac- curacy can chaotic, less well understood, and intrinsically less predictable. The recent study of Zhang and Sippel

  18. Turtle Geometry in Computer Graphics and Computer Aided Design Ron Goldman, Scott Schaefer, Tao Ju

    E-print Network

    Ju, Tao

    -Bonnet to curved space-time and Einstein's general theory of relativity [Abelson and diSessa, 1986]. Turtle to motivate affine coordinates and affine transformations, fractal curves and iterated function systems be to used to motivate affine coordinates and affine transformations (Section 5), fractal curves and iterated

  19. Relapse Prevention for Alcohol and Drug Problems: That Was Zen, This Is Tao

    ERIC Educational Resources Information Center

    Witkiewitz, Katie; Marlatt, Alan G.

    2004-01-01

    Relapse prevention, based on the cognitive-behavioral model of relapse, has become an adjunct to the treatment of numerous psychological problems, including (but not limited to) substance abuse, depression, sexual offending, and schizophrenia. This article provides an overview of the efficacy and effectiveness of relapse prevention in the…

  20. doi: 10.3319/TAO.2008.19.3.321(A) * Corresponding author

    E-print Network

    Li, Tim

    -phase relationship between notES And corrESPondEncE Influence of the Sea Surface temperature in the Indian ocean on identification of the roles of sea surface temperature anomaly (SSTA) in the Indian Ocean in contrast in the western Indian Ocean and a cooling in the southeastern Indian Ocean in the boreal summer and fall

  1. Bayesian Sparse Sampling for On-line Reward Optimization Tao Wang TRYSI@CS.UALBERTA.CA

    E-print Network

    Schuurmans, Dale

    Lizotte DLIZOTTE@CS.UALBERTA.CA Michael Bowling BOWLING@CS.UALBERTA.CA Dale Schuurmans DALE learning (Jordan, 1999; Neal, 1996). Flexible Bayesian tools, such as Gaussian process regression (Williams, 1999; Neal, 1996), have had a significant impact on other areas of machine learn- ing research but have

  2. Cluster formation and bulk phase behavior of colloidal dispersions Tao Jiang and Jianzhong Wu*

    E-print Network

    Wu, Jianzhong

    and van der Waals attraction while the longer-ranged repulsion may come from solvation forces, polymer-mediated steric repulsion or elec- trostatic interactions. A competition of the repulsive and at- tractive components of the colloidal forces leads to forma- tion of lamellar and cluster structures similar to those

  3. Automatic Gait Optimization with Gaussian Process Regression Daniel Lizotte, Tao Wang, Michael Bowling, Dale Schuurmans

    E-print Network

    Bowling, Michael

    - stances. The walking surface is critical and can vary in terms of friction, softness, and height variation (e.g., compare con- crete, linoleum, carpet, and grass). Robot platforms them- selves also vary due

  4. Chasing vs. Stalking: Interrupting the Perception of Animacy Tao Gao and Brian J. Scholl

    E-print Network

    Scholl, Brian

    ), and several lines of evi- dence suggest that this ability may reflect a primitive sort of visual processing time, however, the reflexive ability to perceive animacy can be disrupted by particular sorts

  5. On Multidimensional k-Anonymity with Local Recoding Generalization Tian Xia* Yufei Tao

    E-print Network

    Zhang, Donghui

    if a person knows the age and start-year of, for instance, Al- ice, s/he can still obtain the precise salary/his salary. Simply publishing the projection on {Age, Start-year, Salary} is not feasible. This is because of Alice. In this case, Age and Start-year are the quasi-identifier attributes. One remedy is k

  6. Materials Data on Li3TaO4 (SG:139) by Materials Project

    SciTech Connect

    Kristin Persson

    2014-11-02

    Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations

  7. Paper ID# Authors Title Chen Zhao, Yunzhi Xue, Qiuming Tao, Liang

    E-print Network

    Zhu, Hong

    Salnikow. Calculating BPEL Test Coverage through Instrumentation AST_1128 Bernhard Peischl, Franz Wotawa With Mock Objects AST_1133 Suvarshi Bhadra, Alexander Conrad, Charles Hurkes, Brian Kirklin and Gregory

  8. Geologic map of the Ojo Caliente Quadrangle, Rio Arriba and Taos Counties, New Mexico

    SciTech Connect

    Stix, J.

    1986-11-01

    The Ojo Caliente area forms part of the western limb of the Espanola basin within the Rio Grande rift of northern New Mexico (Manley, 1979; May, 1979). The geology consists of Miocene basin-fill sedimentary rocks that rest unconformably on, or are faulted against, Proterozoic crystalline metamorphic rocks. The Miocene rocks dip gently to the southeast, except where the attitudes are controlled by faulting or by the underlying basement topography. The Precambrian and Miocene rocks are unconformably overlain by Quaternary pediment and river gravels, loess, travertine, landslide debris, and alluvium. The Precambrian rocks are faulted into horsts in several areas by north - northeast - trending normal faults.

  9. Kinetic instabilities in the lunar wake: ARTEMIS observations J. B. Tao,1

    E-print Network

    Bonnell, John W.

    in the solar wind, solar wind plasmas that impinge on the Moon are absorbed by the lunar surface, creating of the Moon is sufficiently low that the motion of the solar wind magnetic field does not induce a significant diamagnetic field. Therefore, unlike solar wind plasmas, the solar wind magnetic field penetrates the Moon

  10. Thyroid Disease

    MedlinePLUS

    ... American Thyroid Association. (2014). Thyroid nodules . Rahib, L., Smith, B. D., Aizenberg, R., Rosenzweig, A. B., Fleshman, ... American Thyroid Association. (2014). Thyroid nodules . Rahib, L., Smith, B. D., Aizenberg, R., Rosenzweig, A. B., Fleshman, ...

  11. numbers and SAT Oliver Kullmann

    E-print Network

    Kullmann, Oliver

    Green-Tao numbers and SAT Oliver Kullmann Introduction Green-Tao numbers Transversal extensions The generic boolean translation Green-Tao numbers and SAT Oliver Kullmann Computer Science Department Swansea, 2010 #12;Green-Tao numbers and SAT Oliver Kullmann Introduction Green-Tao numbers Transversal

  12. Herbal compound Naoshuantong capsule attenuates retinal injury in ischemia/reperfusion rat model by inhibiting apoptosis

    PubMed Central

    Huang, Chuangxin; Gao, Yang; Yu, Qiang; Feng, Liangqi

    2015-01-01

    Objectives: Ischemic ophthalmopathy threatens people’s lives and health. The herbal compound medication, Naoshuantong capsule, plays a critical role in the treatment of cardiac-cerebral vascular diseases; however, the roles and mechanisms of action of Naoshuantong capsule in ischemic ophthalmopathy is unknown. The objective of the present study was to determine the effect and mechanism of action of Naoshuantong capsule on ischemic ophthalmopathy in rats. Methods: In this study a rat model of ischemic ophthalmopathy was constructed using a high intra-ocular pressure-induced ischemia/reperfusion model. The effects of Naoshuantong capsule on ischemic ophthalmopathy were detected using electroretinography, and changes in retinal ultrastructure were examined by HE staining and electron microscopy. The mechanism of action of Naoshuantong capsule on ischemic ophthalmopathy was explored by immunofluorescence and real-time PCR. Results: Rat models of ischemic ophthalmopathy were successfully constructed by intra-ocular hypertension, which presented decreased amplitudes of the electroretinogram (ERG-b) wave and total retinal thickness, intracellular damage, increased expression of Bax and caspase 3, and decreased expression of Bcl-2. Treatment with Naoshuantong capsule attenuated the changes and damage to the ischemic retina in the rat model, inhibited the over-expression of Bax and caspase 3, and increased the expression of Bcl-2. Conclusion: Our study indicated that Naoshuantong capsule attenuates retinal damage in rat models of ischemic ophthalmopathy, possibly by inhibiting apoptosis. PMID:26550135

  13. Learning High-Level Planning from Text S.R.K. Branavan, Nate Kushman, Tao Lei, Regina Barzilay

    E-print Network

    Barzilay, Regina

    and the granularity of planning primitives. Consider, for example, text describing a virtual world such as Minecraft2- ning algorithms rely on manually-crafted high-level 2 http://www.minecraft.net/ #12;abstractions

  14. Securing the Destination Sequenced Distance Vector Routing Protocol Tao Wan Evangelos Kranakis P.C. van Oorschot

    E-print Network

    Kranakis, Evangelos

    routing update with any sequence number fraud (larger or smaller) and any distance fraud (shorter, same sequence number fraud); and 2) a distance shorter than the one it received most recently (shorter distance fraud) or the same as the one it received most recently (same distance fraud). However, superSEAD does

  15. Instant Advertising in Mobile Peer-to-Peer Networks Zaiben Chen, Heng Tao Shen, Quanqing Xu, Xiaofang Zhou

    E-print Network

    Zhou, Xiaofang

    , Xiaofang Zhou School of Information Technology & Electrical Engineering, University of Queensland) such as petrol price update from a nearby petrol station in the morning, discount information on fruits program, they are probably out of date as they are only available for a quite short period (e.g. petrol

  16. TAO, Vol. 13, No. 3, 313-324, September 2002 Near Real-Time Seismic Damage Assessment of

    E-print Network

    Wu, Yih-Min

    of the peak ground velocity can be mapped within minutes of post-initiation of a strong earthquake Located on the western circum-Pacific seismic belt with a plate convergence rate of 8 cm/ year (Yu et al author address: Dr: Yih-Min Wu, Central Weather Bureau, 64 Kung-Yuan Road, Taipei, Taiwan ROC; E

  17. Geopolitics of Quantum Buddhism: Our Pre-Hydrocarbon Tao Future (No Breakthrough at the Rio+20 Summit)

    ERIC Educational Resources Information Center

    Bajrektarevic, Anis

    2013-01-01

    From Rio to Rio with Kyoto, Copenhagen and Durban in between, the conclusion remains the same: we fundamentally disagree on realities of this planet and the ways we can address them. A decisive breakthrough would necessitate both wider contexts and a larger participatory base so as to identify problems, formulate policies, and broaden and…

  18. WHYPER: Towards Automating Risk Assessment of Mobile Applications Rahul Pandita, Xusheng Xiao, Wei Yang, William Enck, Tao Xie

    E-print Network

    Xie, Tao

    .yang}@ncsu.edu {enck, xie}@csc.ncsu.edu Abstract Application markets such as Apple's App Store and Google's Play Store the risk assess- ment of mobile applications. 1 Introduction Application markets such as Apple's App Store malware. To address market-security issues, the two predom- inant smartphone platforms (Apple and Google

  19. Multifunctional organic phototransistor-based nonvolatile memory achieved by UV/ozone treatment of the Ta?O? gate dielectric.

    PubMed

    Liu, Xiaohui; Zhao, Haoyan; Dong, Guifang; Duan, Lian; Li, Dong; Wang, Liduo; Qiu, Yong

    2014-06-11

    An organic phototransistor (OPT) shows nonvolatile memory effect due to its novel optical writing and electrical erasing processes. In this work, we utilize an organic light-emitting diode (OLED) as the light source to investigate OPT-based memory (OPTM) performance. It is found that the OPTM can be used as either flash memory or write-once read-many-times memory by adjusting the properties of the Ta2O5 gate dielectric layer. UV/ozone treatment is applied to effectively change dielectric properties of the Ta2O5 film. The mechanisms for this are examined by X-ray photoelectron spectroscopy and capacitance-voltage measurement. It turns out that the densities of oxygen vacancies and defects in the first 1.8 nm Ta2O5 films near the Ta2O5/semiconductor interface are reduced. Furthermore, for the first time, we use this multifunctional OPTM, which unites the photosensitive and memory properties in one single device, as an optical feedback system to tune the brightness of the OLED. Our study suggests that these OPTMs have potential applications in tuning the brightness uniformity, improving the display quality and prolonging the lifetime of flat panel displays. PMID:24813352

  20. TAO, Vol. 11, No. 4, 753-764, December 2000 A Rapid Method for the Determination of 137

    E-print Network

    Huh, Chih-An

    - ronments from atomic bomb tests, nuclear accidents, and nuclear waste disposal. As an ele- ment of the Cs can be determined by atomic absorption spectrometry or by gravimetric measurement of H2 PtCl6

  1. ANIR: Infrared-Optical Simultaneous Imager for miniTAO 1 m Telescope at an Altitude of 5640 m

    SciTech Connect

    Motohara, Kentaro; Konishi, Masahiro; Mitani, Natsuko; Sako, Shigeyuki; Uchimoto, Yuka K.; Toshikawa, Koji; Minezaki, Takeo; Tanabe, Toshihiko; Miyata, Takashi; Koshida, Shintaro; Nakamura, Tomohiko; Asano, Kentaro; Yoshii, Yuzuru; Doi, Mamoru; Kohno, Kotaro; Tanaka, Masuo; Kawara, Kimiaki; Handa, Toshihiro; Ohsawa, Ryou; Umeda, Hideyuki

    2010-10-15

    Early follow-up observations of gamma-ray bursts (GRBs) in wide wavelength range, especially from the optical to the near infrared (NIR) bands, are crucial for search of high-redshift GRBs by detecting their Lyman limit break. For this purpose, we have developed a NIR/optical simultaneous imager called ANIR (Atacama Near InfraRed camera) for the University of Tokyo Atacama 1.0 m telescope. Installed at the summit of Co. Chajnantor (5640 m altitude) in northern Chile, this telescope is the world's highest optical/NIR observatory. ANIR saw the first light in June 2009, and several observing runs have been carried out for performance verification as well as scientific observations. During the run, we have successfully detected an optical/NIR afterglow of GRB091018. Thanks to the excellent seeing (median {approx}0''.8), 5{sigma} limiting magnitudes reach 23.3, 20.6, and 20.8 mag(AB) in the B, J and Ks bands, respectively, with 600 sec exposure.

  2. High-density organic light emitting diodes by nanoimprint technology Krutarth Trivedi, Caleb Nelson, Li Tao, Mathew Goeckner, Walter Hua)

    E-print Network

    Hu, Wenchuang "Walter"

    from complicated or impractical fabrication as well as charge spreading which causes the emissive area maintaining uncomplicated fabrication. Our processes are centered on functional polymer separation between developed a low-temperature UV nanoimprint process to pattern Su-8 structures to achieve functional polymer

  3. TAO, Vol. 15, No. 3, 545-562, September 2004 Preliminary Results of the iSTEP Program on Integrated

    E-print Network

    Chen, Yuh-Ing

    plates means that Taiwan will inevitably face earthquake hazards in the future. The 1999 Chi on Integrated Search for Taiwan Earthquake Precursors Yi-Ben Tsai 1, *, Jann-Yenq Liu 2,3 , Kuo-Fong Ma 1@geps.gep.ncu.edu.tw The predictability of earthquakes has been a hotly debated question in earthquake science for some time. The answer

  4. Retrofitting Unit Tests for Parameterized Unit Madhuri R. Marri, Suresh Thummalapenta, Tao Xie, Nikolai Tillmann, Jonathan de Halleux

    E-print Network

    Young, R. Michael

    PUTs (4.0 KLOC). Along with achieving higher branch coverage (a maximum increase of 52% for one class automatic test-generation tools alone. I. INTRODUCTION Unit tests are widely adopted in software industry is still a common practice in software industry. When writing unit tests manually, developers can use

  5. SQLUnitGen: SQL Injection Testing Using Static and Dynamic Analysis Yonghee Shin Laurie Williams Tao Xie

    E-print Network

    Xie, Tao

    SQLUnitGen: SQL Injection Testing Using Static and Dynamic Analysis Yonghee Shin Laurie Williams implemented a prototype of a SQL injection vulnerability detection tool, SQLUnitGen, which we compared in 2002-6 were input manipulation vulnerabilities, such as SQL injection, cross site scripting (XSS

  6. Insights from SMPY's Greatest Former Child Prodigies: Drs. Terence ("Terry") Tao and Lenhard ("Lenny") Ng Reflect on Their Talent Development

    ERIC Educational Resources Information Center

    Muratori, Michelle C.; Stanley, Julian C.; Ng, Lenhard; Ng, Jack; Gross, Miraca U. M.; Tao, Terence; Tao, Billy

    2006-01-01

    If the academic needs of the most profoundly gifted students can be met through the use of existing educational practices, specialists in gifted education can assume that the educational needs of less able, but still academically talented, students can also be met by using some combination of these strategies as well. This paper illustrates the…

  7. 77 FR 38375 - Notice of Availability of the Final Environmental Impact Statement (FEIS) for the Taos Regional...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    .... All comments on the FEIS are to be submitted to Mr. Dean McMath of the FAA, at the address shown in... COMMENTS: Dean McMath, ASW-613, Regional Environmental Programs Manager, Federal Aviation...

  8. Movement as a Metaphor: How Persistence, the Tao, and the Wisdom of the Ostrich Helped Build School Dance Programs

    ERIC Educational Resources Information Center

    Kaufman, Karen

    2011-01-01

    Those who advocate for dance in education inevitably face many roadblocks, including ignorance of how dance can contribute to education, implementation of standardized performance assessments, lack of funding, entrenched issues of politics and power, and fear and discomfort about the body. It is dance teachers' responsibility to enlighten,…

  9. Optimizing unit test execution in large software programs using dependency analysis

    E-print Network

    Kim, Taesoo

    Tao is a system that optimizes the execution of unit tests in large software programs and reduces the programmer wait time from minutes to seconds. Tao is based on two key ideas: First, Tao focuses on efficiency, unlike ...

  10. numbers and SAT Oliver Kullmann

    E-print Network

    Kullmann, Oliver

    Green-Tao numbers and SAT Oliver Kullmann Introduction Green-Tao numbers Transversal extensions The generic boolean translation Green-Tao numbers and SAT Oliver Kullmann Computer Science Department Swansea University SAT 2010 Edinburgh, July 12, 2010 #12;Green-Tao numbers and SAT Oliver Kullmann Introduction Green

  11. Statistical thermodynamics of 1-butanol, 2-methyl-1-propanol, and butanal Prasenjit Seal, Ewa Papajak, Tao Yu, and Donald G. Truhlar

    E-print Network

    Truhlar, Donald G

    Statistical thermodynamics of 1-butanol, 2-methyl-1-propanol, and butanal Prasenjit Seal, Ewa OF CHEMICAL PHYSICS 136, 034306 (2012) Statistical thermodynamics of 1-butanol, 2-methyl-1-propanol investigation is to calculate partition functions and thermodynamic quan- tities, viz., entropy, enthalpy, heat

  12. Complete set of material constants of single domain (K, Na)(Nb, Ta)O3 single crystal and their orientation dependence

    PubMed Central

    Zheng, Limei; Li, Shiyang; Sang, Shijing; Wang, Junjun; Huo, Xiaoqing; Wang, Rui; Yuan, Zhongyuan; Cao, Wenwu

    2014-01-01

    A self-consistent complete set of dielectric, piezoelectric, and elastic constants for single domain Ta modified (K, Na)NbO3 (KNN) crystal was determined. This full set constant for single domain KNN-based crystals allowed the prediction of orientation dependence of the longitudinal dielectric, piezoelectric, elastic coefficients, and electromechanical coupling factors. The maximum piezoelectric and electromechanical properties were found to exist near [001]C. In addition, material constants of [001]C poled domain engineered single crystal with 4?mm symmetry were experimentally measured and compared with the calculated values. Based on this, extrinsic contribution to the piezoelectricity was estimated to be ?20%. PMID:25489119

  13. Complete set of material constants of single domain (K, Na)(Nb, Ta)O3 single crystal and their orientation dependence.

    PubMed

    Zheng, Limei; Li, Shiyang; Sang, Shijing; Wang, Junjun; Huo, Xiaoqing; Wang, Rui; Yuan, Zhongyuan; Cao, Wenwu

    2014-11-24

    A self-consistent complete set of dielectric, piezoelectric, and elastic constants for single domain Ta modified (K, Na)NbO3 (KNN) crystal was determined. This full set constant for single domain KNN-based crystals allowed the prediction of orientation dependence of the longitudinal dielectric, piezoelectric, elastic coefficients, and electromechanical coupling factors. The maximum piezoelectric and electromechanical properties were found to exist near [001] C . In addition, material constants of [001] C poled domain engineered single crystal with 4?mm symmetry were experimentally measured and compared with the calculated values. Based on this, extrinsic contribution to the piezoelectricity was estimated to be ?20%. PMID:25489119

  14. Algebraic Differential Fault Attacks on LED using a Single Fault Injection Xinjie Zhaoa,, Shize Guob, Fan Zhangc, Tao Wanga, Zhijie Shic, Keke Jia

    E-print Network

    International Association for Cryptologic Research (IACR)

    Algebraic Differential Fault Attacks on LED using a Single Fault Injection Xinjie Zhaoa,, Shize Abstract This paper proposes a new fault attack technique on the LED block cipher using a single fault it as algebraic differential fault attack (ADFA). Firstly, a boolean equation set is constructed for LED using

  15. ZHANG, TAO. Using Measures of Situation Awareness to Characterize Mental Models in Inductive Reasoning Tasks. (Under the direction of Dr. David B. Kaber.)

    E-print Network

    Kaber, David B.

    a multitasking scenario in virtual reality (VR), was conducted in which participants were required to attend in long-term memory (LTM). The experiment results provided further empirical evidence of the utility of SA

  16. Multi-finger flexible graphene field effect transistors with high bendability Jongho Lee, Li Tao, Kristen N. Parrish, Yufeng Hao, Rodney S. Ruoff et al.

    E-print Network

    beyond system functionality, concerning cost, electronic waste, environmen- tal impact, weight://apl.aip.org/resource/1/APPLAB/v101/i25 Published by the American Institute of Physics. Related Articles Complementary-film transistors Appl. Phys. Lett. 102, 052905 (2013) Additional information on Appl. Phys. Lett. Journal Homepage

  17. P-127: Stabilization of Azodye Alignment Layer for Liquid Crystal Display Lishuang Yao, Tao Du, Vladimir Chigrinov, and Hoi Sing Kwok

    E-print Network

    to that of rubbed polyimide film is obtained without using a contact process. The poor photostability known a fine alignment film same as with pure azodye material. After exposure with two steps in two special of crosslinking material was also introduced to this mixture alignment film. Hence an easy and efficient way

  18. Doping dependent NH3 sensing of indium oxide nanowires Daihua Zhang, Chao Li, Xiaolei Liu, Song Han, Tao Tang, and Chongwu Zhoua)

    E-print Network

    Zhou, Chongwu

    is known to be an n-type semiconductor in its nonstoichiometric form due to oxygen vacancy doping.1 Its low-dimensional of semiconducting metal oxide materials. © 2003 American Institute of Physics. DOI: 10.1063/1.1604194 Indium oxide

  19. Viscous effects in droplet-ejecting capillary waves Christopher L. Goodridge,* W. Tao Shi, H. G. E. Hentschel, and Daniel P. Lathrop

    E-print Network

    Lathrop, Daniel P.

    observed in liquids with a two decade range in viscosity, a factor of 3 change in surface tension, and over which depend on only surface tension and forcing frequency while high viscosity fluids have thresholds surface tension / and the ki- nematic viscosity of the fluid / , as well as the applied forcing frequency

  20. MJO Signals in Latent Heating: Results from TRMM Retrievals CHIDONG ZHANG,* JIAN LING,* SAMSON HAGOS,*,1 WEI-KUO TAO,# STEVE LANG,#

    E-print Network

    Zhang, Chidong

    minimum in the deep components over the Maritime Continent. The shallow components of the MJO differ) is commonly viewed as driven by convection­circulation coupling or interaction. Such a perception comes mainly from observed coherence be- tween winds and convective signals, such as outgoing longwave radiation

  1. J. Tao, T. Tan, and R.W. Picard (Eds.): ACII 2005, LNCS 3784, pp. 1 7, 2005. Springer-Verlag Berlin Heidelberg 2005

    E-print Network

    Tzanetakis, George

    conductors, surgeons or even nuclear power plant workers are bored or not paying attention [3 examples [1]. Imagine global positioning systems in cars re-routing drivers to less crowded, safer streets

  2. Deformation Induced Solid-Solid Phase Transitions in Gamma Boron Qi An, William A. Goddard, III,* Hai Xiao, and Tao Cheng

    E-print Network

    Goddard III, William A.

    to such unique properties as high hardness, high melting temperature, and strong absorbance of neutrons.1 particular forms of boron that exhibit valuable properties by alloying with other elements that fit when zero-point vibrational energy or its entropy of partial occupancy is taken into account.8

  3. Experimental Realization of an Optical One-Way Barrier for Neutral Atoms Jeremy J. Thorn, Elizabeth A. Schoene, Tao Li, and Daniel A. Steck

    E-print Network

    Steck, Daniel A.

    but reflected from the other, is a realization of Maxwell's demon and has important implications for cooling of Maxwell's demon [7,11­13]. In this thought-experiment, the demon manipulates a trapdoor in a wall dividing a container of gas. The demon could use the trapdoor as a one-way barrier to reduce the space occupied

  4. -sheet-like formation during the mechanical unfolding of prion protein Weiwei Tao, Gwonchan Yoon, Penghui Cao, Kilho Eom, and Harold S. Park

    E-print Network

    Park, Harold S.

    ://scitation.aip.org/content/aip/journal/jcp/143/12?ver=pdfcov Published by the AIP Publishing Articles you may be interested in Exploring the role (2005); 10.1063/1.2046609 This article is copyrighted as indicated in the article. Reuse of AIP content aggregate into a variety of forms of amyloid plaques in the brain. The mature human PrP (huPrP, 23- 230) has

  5. Measuring Opinion Relevance in Latent Topic Space Wei Cheng, Xiaochuan Ni, Jian-Tao Sun, Xiaoming Jin, Hye-Chung Kum, Xiang Zhang, Wei Wang

    E-print Network

    Wang, Wei

    query and opinion-carrying words. These approaches may cause two problems: 1) opinions in the returned.0 applications, users are involved in many online activities and are contributing various kinds of data to the Web, for example, user opinion data. It is common practice for people to write reviews on shopping

  6. Sevoflurane-Induced Structural Changes in a Four-R-Helix Bundle Protein Ravindernath Pidikiti, Tao Zhang, Krishna M. G. Mallela, Mohammad Shamim,| Konda S. Reddy, and

    E-print Network

    Mallela, Krishna M. G.

    cryomicroscopy studies on the related nicotinic acetylcholine receptor from Torpedo marmorata at 4 Å resolution such as the nicotinic acetylcholine receptor (7, 8), the -aminobutyric acid type A receptor (9), and bovine rhodopsin the Cys-loop ligand-gated ion channels such as the -aminobutyric acid type A receptor and the homologous

  7. Annealing kinetics of electrodeposited lithium dendrites Asghar Aryanfar, Tao Cheng, Agustin J. Colussi, Boris V. Merinov, William A. Goddard III, and Michael R.

    E-print Network

    Goddard III, William A.

    the ongoing research aims to develop novel Li-air, Li-S, and flow battery technologies, the dendrite problem, and magnesium battery anode materials related to possible dendrite growth J. Chem. Phys. 141, 174710 (2014); 10-lasting and high energy density batteries.1 Particularly, pure lithium (Li0 ) is the battery anode material

  8. 76 FR 76972 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-09

    ...Guidance for the Management of Public Lands and Resource Administered by Taos Field Office, Colfax, Harding, Los Alamos, Mora, Rio Arriba, Santa Fe, Taos and Union Counties, NM, Review Period Ends: 01/09/2012, Contact: Brad Higdon...

  9. 75 FR 33299 - Environmental Impacts Statements; Notice Of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-11

    ...Guidance for the Management of Public Lands and Resource Administered by Taos Field Office, Colfax, Harding, Los Alamos, Mora, Rio Arriba, Santa Fe, Taos and Union Counties, NM, Comment Period Ends: 09/08/2010, Contact: Brad Higdon...

  10. 75 FR 67966 - Notice of a Project Waiver of Section 1605 (Buy American Requirement) of the American Recovery...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-04

    ...2009 (ARRA) to the Town of Taos, NM AGENCY...satisfactory quality] to the Town of Taos (``Taos...the EPA Region 6, Water Quality Protection...determined that the City's waiver request...determined that the City's request, though...jobs. The Region 6 Water Quality...

  11. 14. Photocopy of architectural drawing (from Albuquerque Area Indian Health ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photocopy of architectural drawing (from Albuquerque Area Indian Health Service, Division of Health Facilities, Albuquerque, New Mexico) Mayers, Murray, and Phillip, Architects, New York, N&, 1934 Foundation Plan - Taos Indian Health Center, 0.3 mile south-southwest of Pueblos Plaza, Taos Pueblo, Taos County, NM

  12. 15. Photocopy of architectural drawing (from Albuquerque Area Indian Health ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Photocopy of architectural drawing (from Albuquerque Area Indian Health Service, Division of Health Facilities, Albuquerque, New Mexico) Mayers, Murray, and Phillip, Architects, New York, NY, 1934 First Floor - plumbing - Taos Indian Health Center, 0.3 mile south-southwest of Pueblos Plaza, Taos Pueblo, Taos County, NM

  13. 16 Photocopy of architectural drawing (from Albuquerque Area Indian Health ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16 Photocopy of architectural drawing (from Albuquerque Area Indian Health Service, Division of Health Facilities, Albuquerque, New Mexico) Mayers Murray, and Phillip, Architects, New York, NY, 1934 first floor mechanical plan - heating - Taos Indian Health Center, 0.3 mile south-southwest of Pueblos Plaza, Taos Pueblo, Taos County, NM

  14. 17. Photocopy of architectural drawing (from Albuquerque Area Indian Health ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. Photocopy of architectural drawing (from Albuquerque Area Indian Health Service, Division of Health Facilities, Albuquerque, New Mexico) Mayers, Murray, and Phillip, Architects, New York, NY, 1934 Elevations - Taos Indian Health Center, 0.3 mile south-southwest of Pueblos Plaza, Taos Pueblo, Taos County, NM

  15. 18. Photocopy of architectural drawing (from Albuquerque Area Indian Health ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Photocopy of architectural drawing (from Albuquerque Area Indian Health Service, Division of Health Facilities, Albuquerque, New Mexico) Mayers, Murray, and Phillip, Architects, New York, NY, 1934 Detail sheet - Taos Indian Health Center, 0.3 mile south-southwest of Pueblos Plaza, Taos Pueblo, Taos County, NM

  16. A SUPERSYMMETRIC VIEW OF THE HIGGS HUNTING

    E-print Network

    Fygenson, Deborah Kuchnir

    A SUPERSYMMETRIC VIEW OF THE HIGGS HUNTING Tao Liu UC @ Santa Barbara UC @ Santa Barbara Feb. 2nd, 2011 Thursday, February 2, 2012 #12;Tao Liu (UC@Santa Barbara) Hunting for the Higgs 2 Higgs Boson) Thursday, February 2, 2012 #12;Tao Liu (UC@Santa Barbara) Hunting for the Higgs 3 ! At hadron colliders

  17. 2 6 / J U I L L E T-AO U T 2 0 0 2 L A R E C H E RC H E 3 5 5 S p c i a l m e r

    E-print Network

    Kirschvink, Joseph L.

    les roches par l'écoulement des glaces, cailloux abandonnés par des icebergs, etc. Plus étrange, D. Mawson et B. Harland avaient trouvé, mélangés aux débris glaciaires, des frag- ments de roches composées de carbonates de cal- cium (calcaires) ou de magnésium (dolomites), les- quelles se forment dans les

  18. Infrared properties of ferropericlase Mg1-xFexO: Experiment and theory Tao Sun,1,* Philip B. Allen,1 David G. Stahnke,2 Steven D. Jacobsen,3 and Christopher C. Homes4

    E-print Network

    Johnson, Peter D.

    of such a disordered anharmonic crystal. In this paper we report the temperature-dependent infra- red reflectance.8 eV,2 ferropericlase has crystal field levels and charge transfer bands at much lower energies due states, the harmonic eigen- states of the disordered crystal do not necessarily have a well-defined wave

  19. Questa Baseline and Pre-Mining Ground-Water Quality Investigation. 24. Seismic Refraction Tomography for Volume Analysis of Saturated Alluvium in the Straight Creek Drainage and Its Confluence With Red River, Taos County, New Mexico

    USGS Publications Warehouse

    Powers, Michael H.; Burton, Bethany L.

    2007-01-01

    As part of a research effort directed by the New Mexico Environment Department to determine pre-mining water quality of the Red River at a molybdenum mining site in northern New Mexico, we used seismic refraction tomography to create subsurface compressional-wave velocity images along six lines that crossed the Straight Creek drainage and three that crossed the valley of Red River. Field work was performed in June 2002 (lines 1-4) and September 2003 (lines 5-9). We interpreted the images to determine depths to the water table and to the top of bedrock. Depths to water and bedrock in boreholes near the lines correlate well with our interpretations based on seismic data. In general, the images suggest that the alluvium in this area has a trapezoidal cross section. Using a U.S. Geological Survey digital elevation model grid of surface elevations of this region and the interpreted elevations to water table and bedrock obtained from the seismic data, we generated new models of the shape of the buried bedrock surface and the water table through surface interpolation and extrapolation. Then, using elevation differences between the two grids, we calculated volumes of dry and wet alluvium in the two drainages. The Red River alluvium is about 51 percent saturated, whereas the much smaller volume of alluvium in the tributary Straight Creek is only about 18 percent saturated. When combined with average ground-water velocity values, the information we present can be used to determine discharge of Straight Creek into Red River relative to the total discharge of Red River moving past Straight Creek. This information will contribute to more accurate models of ground-water flow, which are needed to determine the pre-mining water quality in the Red River.

  20. Decoupling of Structural and Electronic Phase Transitions in VO2 Zhensheng Tao, Tzong-Ru T. Han, Subhendra D. Mahanti, Phillip M. Duxbury, Fei Yuan, and Chong-Yu Ruan*

    E-print Network

    Wu, Junqiao

    have broken orbital degeneracy that is tunable via structural symmetry, composition, and dimensionality d orbitals participating in a Peierl's dimerization along the z axis are the xz and yz orbitals instead of the xy orbitals as put forward by Goodenough [15] and elucidated FIG. 1 (color online). (a) VO2

  1. A-SITE-AND/OR B-SITE-MODIFIED PBZRTIO3 MATERIALS AND (PB, SR, CA, BA, MG) (ZR, TI,NB, TA)O3 FILMS HAVING UTILITY IN FERROELECTRIC RANDOM ACCESS MEMORIES AND HIGH PERFORMANCE THIN FILM MICROACTUATORS

    NASA Technical Reports Server (NTRS)

    Roeder, Jeffrey F. (Inventor); Chen, Ing-Shin (Inventor); Bilodeau, Steven (Inventor); Baum, Thomas H. (Inventor)

    2004-01-01

    A modified PbZrTiO.sub.3 perovskite crystal material thin film, wherein the PbZrTiO.sub.3 perovskite crystal material includes crystal lattice A-sites and B-sites at least one of which is modified by the presence of a substituent selected from the group consisting of (i) A-site substituents consisting of Sr, Ca, Ba and Mg, and (ii) B-site substituents selected from the group consisting of Nb and Ta. The perovskite crystal thin film material may be formed by liquid delivery MOCVD from metalorganic precursors of the metal components of the thin film, to form PZT and PSZT, and other piezoelectric and ferroelectric thin film materials. The thin films of the invention have utility in non-volatile ferroelectric memory devices (NV-FeRAMs), and in microelectromechanical systems (MEMS) as sensor and/or actuator elements, e.g., high speed digital system actuators requiring low input power levels.

  2. Maximinus Daia, a Roman emperor who may have had Graves' disease and died of a thyrotoxic crisis.

    PubMed

    Papapetrou, Peter D

    2013-01-01

    Evidence is presented that the Roman emperor Maximinus Daia had Graves' disease and died of severe thyrotoxicosis. The information about this emperor's terminal illness is drawn from the writings of the 4th century writers Eusebius and Lactantius. An existing statue indicates that the emperor had bilateral Graves' ophthalmopathy. PMID:23624140

  3. Exophthalmos: A Forgotten Clinical Sign of Cushing's Syndrome.

    PubMed

    Giugni, Aldo Schenone; Mani, Shylaja; Kannan, Subramanian; Hatipoglu, Betul

    2013-01-01

    Exophthalmos is typically associated with Graves' ophthalmopathy. Although originally described by Harvey Cushing, exophthalmos is an underappreciated sign of Cushing's syndrome. We present a case of a 38-year-old female who presented with severe bilateral proptosis and was subsequently diagnosed with Cushings disease. We discuss the possible mechanisms causing exophthalmos in patients with either endogenous or exogenous hypercortisolemia. PMID:23555062

  4. Ophthalmic Manifestations of Leukemia in a Tertiary Hospital Population of Adult Nigerian Africans

    PubMed Central

    Eze, Boniface I.; Ibegbulam, Godswill O.; Ocheni, Sunday

    2010-01-01

    Purpose: To determine the prevalence and pattern of leukemic ophthalmopathy among adults at the University of Nigeria Teaching Hospital (UNTH), Enugu, south-eastern, Nigeria. Materials and Methods: This prospective, observational case series surveyed adult leukemia patients presenting at UNTH’s departments of Hematology/Immunology and Ophthalmology from July 2003 to August 2008. The demographic profile, clinical data from for each individual in the cohort were statistically collated and analyzed. A P <0.05 was considered as statistically significant. Results: There were 72 participants (45 males and 27 females), aged 32.7 ± 9.8 years (range, 18 years to 72 years). Leukemic ophthalmopathy was present in 77.8% of subjects. The leading ophthalmic manifestations of leukemia were retinal vascular abnormalities in 50.0% of subjects, conjunctival pallor in 27.8% of subjects, sub-conjunctival hemorrhage in 19.4% of subjects, and retinal hemorrhage in 16.7% of subjects. Ocular co-morbidity was present in 47.2% of subjects. Vision loss occurred in 37.5% of subjects, of which 32.1% was leukemia related, and the remaining due to ocular co-morbidity. Leukemic ophthalmopathy was more prevalent in chronic leukemia (P <0.05), frequently affected the ocular posterior segment (P < 0.05), and often resulted from secondary hematologic complications (P <0.05). There was no gender difference in the prevalence of leukemia (P = 0.0822) or leukemic ophthalmopathy (P = 0.6624). Conclusion: The prevalence of leukemic ophthalmopathy in Enugu is high. It is often associated with significant ocular co-morbidity and vision loss. These have implications for clinicians involved in leukemia management. Early diagnosis and regular ophthalmic examinations are recommended to optimize treatment outcomes. PMID:21180433

  5. Pretibial myxedema: pathophysiology and treatment options.

    PubMed

    Fatourechi, Vahab

    2005-01-01

    Pretibial myxedema or localized myxedema or thyroid dermopathy is an autoimmune manifestation of Graves' disease. It also occasionally occurs in Hashimoto's thyroiditis. Lesions of thyroid dermopathy are usually asymptomatic and have only cosmetic importance. Advanced forms of dermopathy are associated with elephantiasis or thyroid acropachy. Almost all cases of thyroid dermopathy are associated with relatively severe ophthalmopathy. Usually ophthalmopathy appears first and dermopathy much later. All patients with localized myxedema have high serum concentrations of thyroid-stimulating hormone receptor antibodies, indicating the severity of the autoimmune condition. Occurrence of thyroid dermopathy in areas other than pretibial skin indicates a systemic process. Similar to Graves' ophthalmopathy, thyroid-stimulating hormone receptors in the connective tissue may be the antigen responsible for the immune process. Both humoral and cellular immune mechanisms are involved in the stimulation of fibroblasts and the production of large amounts of glycosaminoglycans. Localization in the pretibial area relates to mechanical factors and dependent position. Diagnosis of thyroid dermopathy is based on signs and typical pretibial skin lesions in association with a history of Graves' hyperthyroidism and ophthalmopathy. In some cases, skin biopsy is needed for confirmation. The lesions are usually mild and are overshadowed by more symptomatic ophthalmopathy. Most cases of thyroid dermopathy do not require any therapy. In mildly severe symptomatic cases and when there is cosmetic concern, topical corticosteroids applied under occlusive dressing are beneficial. In more severe cases, systemic immunomodulation may be necessary; however, conclusive evidence for long-term efficacy of these modalities is lacking. When significant edema and elephantiasis are present, local compressive therapy may have added benefit. In mild cases that do not require treatment, 50% of patients achieve complete remission after several years. Severe cases that receive topical corticosteroids or other therapies do not have a better outcome than untreated milder cases. Current treatment modalities for thyroid dermopathy and acropachy are at best palliative. Better and safer means of immunomodulation are needed. PMID:16252929

  6. September 24-26, 1984 TABLE OF CONTENTS

    E-print Network

    ··············.....····.·...·...··········...... 146 Future Directions of Security for Sperry Series 1100 Computers, T.M.P. Lee·································270 Workstation Application, Dr. Roger Schell and Dr. Tien Tao··········277 to Enforce

  7. Journal of Neuroscience Methods xxx (2006) xxxxxx 3D volume reconstruction of a mouse brain from histological

    E-print Network

    Ju, Tao

    2006-01-01

    histological sections using warp filtering Tao Jue,, Joe Warrena, James Carsonf, Musodiq Bellod, Ioannis; Filtering; Image warping; Dynamic programming; Histology 1. Introduction In medical imaging, volumetric data

  8. Thermal Acoustic Oscillation: Causes, Detection, Analysis, and Prevention

    NASA Technical Reports Server (NTRS)

    Christie, R. J.; Hartwig, J. W.

    2014-01-01

    Thermal Acoustic Oscillations (TAO) can occur in cryogenic systems and produce significant sources of heat. This source of heat can increase the boil off rate of cryogenic propellants in spacecraft storage tanks and reduce mission life. This paper discusses the causes of TAO, how it can be detected, what analyses can be done to predict it, and how to prevent it from occurring.The paper provides practical insight into what can aggravate instability, practical methods for mitigation, and when TAO does not occur. A real life example of a cryogenic system with an unexpected heat source is discussed, along with how TAO was confirmed and eliminated.

  9. PRECAMBRIAN GEOLOGY OF THE OJO CALIENTE QUADRANGLE,

    E-print Network

    Treiman, Allan H.

    PRECAMBRIAN GEOLOGY OF THE OJO CALIENTE QUADRANGLE, RIO ARRIBA AND TAOS COUNTIES, NEW MEXICO A THESIS SUBMITTED TO THE DEPARTMENT OF GEOLOGY AND THE COMMITTEE ON GRADUATE STUDIES OF STANFORD Treiman June 1977 PRECAMBRIAN GEOLOGY OF THE OJO CALIENTE QUADRANGLE, RIO ARRIBA AND TAOS COUNTIES, NEW

  10. Dynamic Modeling of a Part Mating Problem: Threaded Fastener Insertion

    E-print Network

    Fearing, Ron

    given by the kinematic description. The simulationwill be used to investigatethe be- havior of the bolt to a study by Nevins and Whitney Nevins 80] the insertion and tightening of threaded fasteners is one presented. Tao et. al. Tao 90] implemented a bolt threading operation with generalized sti ness controlled

  11. Awards conferred to Ph.D. Graduates at the BCB Graduates Reception Friday, May 11, 2007

    E-print Network

    Tao, Yizhi Jane

    Pathogen Candida albicans by CTA4, a DNA-Binding Protein Transcription Factor" (Gustin) Jeanne Rasbery (Tao) #12;Photos from the graduate reception Junhua Pan (Tao) #12;The 6th Annual Rice Undergraduate Research Symposium Monday, April 16, 2007 Grand Hall of the Rice Memorial Center, Rice University Award

  12. 75 FR 32963 - Notice of Availability of the Draft Resource Management Plan and Draft Environmental Impact...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-10

    ...estate and 1.5 million acres of mineral estate administered by the Taos Field Office within Colfax, Harding, Los Alamos, Mora, Rio Arriba, Santa Fe, Taos, and Union counties in northern New Mexico. This land use plan would replace the current...

  13. 76 FR 75556 - Notice of Availability of the Proposed Resource Management Plan and Final Environmental Impact...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-02

    ...estate and 1.5 million acres of mineral estate administered by the Taos Field Office within Colfax, Harding, Los Alamos, Mora, Rio Arriba, Santa Fe, Taos, San Miguel, and Union Counties in northern New Mexico. This land use plan would replace...

  14. Journal Publications: 1. Honggang Zhang, Kaili Zhao, Yi-Zhe Song: Text Extraction from Natural Scene Image: A Survey.

    E-print Network

    Song, Yi-Zhe

    Journal Publications: 1. Honggang Zhang, Kaili Zhao, Yi-Zhe Song: Text Extraction from Natural, Honggang Zhang, Tao Xiang and Yi-Zhe Song. Sketching By Perceptual Grouping. International Conference Vision Conference (BMVC), 2013. Bristol, UK. In press 13. Yonggang Qi, Jun Guo, Honggang Zhang, Tao Xiang

  15. Turning Patrons into Partners When Choosing an Integrated Library System

    ERIC Educational Resources Information Center

    Ryan, Terry

    2004-01-01

    UCLA, which has one of the top 10 research libraries in the country, has been using Taos software since 1996. However in 2001, Sirsi Corp. announced that it was freezing development on Taos software. As the associate university librarian for information technology at UCLA, the author relates that it was his responsibility to lead the way through…

  16. RICE UNIVERSITY Building a 3D Atlas of the Mouse Brain

    E-print Network

    Ju, Tao

    RICE UNIVERSITY Building a 3D Atlas of the Mouse Brain by Tao Ju A Thesis Submitted in Partial, Texas April, 2005 #12;Building a 3D Atlas of the Mouse Brain Tao Ju Abstract Building and studying 3D representations of anatomical structures, such as the brain, plays an important role in modern biology and medical

  17. Compressive video sensing with limited measurements

    E-print Network

    Compressive video sensing with limited measurements Tao Li Xiaohua Wang Weihe Wang Aggelos K://spiedl.org/terms #12;Compressive video sensing with limited measurements Tao Li Beijing Institute of Technology School Department of EECS Evanston, Illinois 60201 Abstract. Compressive sensing (CS) is an innovative technology

  18. Probing 3'-ssDNA Loop Formation in E. coli RecBCD/RecBC-DNA Com-plexes using Non-natural DNA: A Model for "Chi" Recognition Complexes

    E-print Network

    Ju, Tao

    -natural DNA: A Model for "Chi" Recognition Complexes C. Jason Wong, Rachel L. Rice, Nathan A. Baker, Tao Ju for "Chi" Recognition Complexes C. Jason Wong# , Rachel L. Rice , Nathan A. Baker , Tao Ju and Timothy M (NTP) binding and hydrolysis to unwind double-stranded (ds) DNA to form s

  19. ON THE ACCURACY OF THE FINITE VOLUME ELEMENT METHOD BASED ON PIECEWISE LINEAR POLYNOMIALS #

    E-print Network

    Ewing, Richard E.

    E. EWING + , TAO LIN # , AND YANPING LIN § SIAM J. NUMER. ANAL. c # 2002 Society for Industrial 77843­3404 (ewing@isc.tamu.edu). This author was supported by NSF grants DMS­9626179, DMS­9706985, DMS, Edmonton, AL T6G 2G1 Canada (ylin@hilbert.math.ualberta.ca). 1865 #12; 1866 RICHARD E. EWING, TAO LIN

  20. The Taiwanese-American Occultation Survey: The Multi-Telescope Robotic Observatory

    E-print Network

    M. J. Lehner; C. -Y. Wen; J. -H. Wang; S. L. Marshall; M. E. Schwamb; Z. -W. Zhang; F. B. Bianco; J. Giammarco; R. Porrata; C. Alcock; T. Axelrod; Y. -I. Byun; W. P. Chen; K. H. Cook; R. Dave; S. -K. King; T. Lee; H. -C. Lin; S. -Y. Wang

    2009-03-16

    The Taiwanese-American Occultation Survey (TAOS) operates four fully automatic telescopes to search for occultations of stars by Kuiper Belt Objects. It is a versatile facility that is also useful for the study of initial optical GRB afterglows. This paper provides a detailed description of the TAOS multi-telescope system, control software, and high-speed imaging.

  1. impact of environmental forcing on the acoustic backscattering strength

    E-print Network

    · surface chlorophyll (SeaWiFS) · SST (TMI) · wind (QuikScat) in situ data · T, S, and current profiles (TAO) · meteo (TAO) · moon phases, sun and moon rise and set times (US Naval Observatory) #12;the equatorial Pacificthe equatorial Pacific Sv variations · different time-scales · light (diurnal cycle, moon cycle

  2. TOOLKIT FOR ADVANCED OPTIMIZATION

    Energy Science and Technology Software Center (ESTSC)

    2000-10-13

    The TAO project focuses on the development of software for large scale optimization problems. TAO uses an object-oriented design to create a flexible toolkit with strong emphasis on the reuse of external tools where appropriate. Our design enables bi-directional connection to lower level linear algebra support (for example, parallel sparse matrix data structures) as well as higher level application frameworks. The Toolkist for Advanced Optimization (TAO) is aimed at teh solution of large-scale optimization problemsmore »on high-performance architectures. Our main goals are portability, performance, scalable parallelism, and an interface independent of the architecture. TAO is suitable for both single-processor and massively-parallel architectures. The current version of TAO has algorithms for unconstrained and bound-constrained optimization.« less

  3. Osteoarthritis at Young Age, a Diagnostic Challenge: A Case of Stickler Syndrome

    PubMed Central

    de Wergifosse, Isabelle; Westhovens, Rene

    2014-01-01

    A young woman presents with severe polyarticular osteoarthritis with relevant family history potentially suggesting a hereditary disease. Previously, the patient’s mother had been diagnosed with rheumatoid arthritis and reported to have suffered from some locomotor problems. Careful clinical evaluation with an extensive personal and familial history pointed towards a diagnosis of Stickler syndrome, an autosomal dominant condition with progressive arthro-ophthalmopathy, (early osteoarthritis and myopia). Following this timely diagnosis, genetic counselling was offered. PMID:25598853

  4. Thermally-assisted-occupation density functional theory with generalized-gradient approximations

    SciTech Connect

    Chai, Jeng-Da

    2014-05-14

    We extend the recently proposed thermally-assisted-occupation density functional theory (TAO-DFT) [J.-D. Chai, J. Chem. Phys. 136, 154104 (2012)] to generalized-gradient approximation (GGA) exchange-correlation density functionals. Relative to our previous TAO-LDA (i.e., the local density approximation to TAO-DFT), the resulting TAO-GGAs are significantly superior for a wide range of applications, such as thermochemistry, kinetics, and reaction energies. For noncovalent interactions, TAO-GGAs with empirical dispersion corrections are shown to yield excellent performance. Due to their computational efficiency for systems with strong static correlation effects, TAO-LDA and TAO-GGAs are applied to study the electronic properties (e.g., the singlet-triplet energy gaps, vertical ionization potentials, vertical electron affinities, fundamental gaps, and symmetrized von Neumann entropy) of acenes with different number of linearly fused benzene rings (up to 100), which is very challenging for conventional electronic structure methods. The ground states of acenes are shown to be singlets for all the chain lengths studied here. With the increase of acene length, the singlet-triplet energy gaps, vertical ionization potentials, and fundamental gaps decrease monotonically, while the vertical electron affinities and symmetrized von Neumann entropy (i.e., a measure of polyradical character) increase monotonically.

  5. Obstruction of the superior mesenteric artery due to emboli from the thoracic aorta in a patient with thromboangiitis obliterans.

    PubMed

    Kamiya, Chiaki; Deguchi, Juno; Kitaoka, Tadashi; Suzuki, Jun; Abe, Keiko; Sato, Osamu

    2014-01-01

    A 48-year-old woman presented at our hospital with acute abdominal pain 3 years after being diagnosed with thromboangiitis obliterans (TAO). Computed tomography revealed occlusion of the superior mesenteric artery (SMA) and multiple kidney infarction with thrombus floating in the thoracic aorta connected with the intercostal artery. Despite emergency embolectomy, further thromboembolism eventually required massive resection of the intestine with jejunostomy and colostomy and permanent intravenous hyper-alimentation therapy. Although TAO rarely involves the large artery, the aorta could be the source of embolization in patients with TAO. PMID:25298837

  6. Obstruction of the Superior Mesenteric Artery Due to Emboli from the Thoracic Aorta in a Patient with Thromboangiitis Obliterans

    PubMed Central

    Kamiya, Chiaki; Kitaoka, Tadashi; Suzuki, Jun; Abe, Keiko; Sato, Osamu

    2014-01-01

    A 48-year-old woman presented at our hospital with acute abdominal pain 3 years after being diagnosed with thromboangiitis obliterans (TAO). Computed tomography revealed occlusion of the superior mesenteric artery (SMA) and multiple kidney infarction with thrombus floating in the thoracic aorta connected with the intercostal artery. Despite emergency embolectomy, further thromboembolism eventually required massive resection of the intestine with jejunostomy and colostomy and permanent intravenous hyper-alimentation therapy. Although TAO rarely involves the large artery, the aorta could be the source of embolization in patients with TAO. PMID:25298837

  7. Discussion of "Carbon benefits of wolfberry plantation on secondary saline land in Jingtai oasis, Gansu - A case study on application of the CBP model" by Yaolin Wang, Chuanyan Zhao, Quanlin Ma, Yingke Li, Hujia Jing, Tao Sun, Eleanor Milne, Mark Easter, Keith Paustian, Hoi Wen Au Yong, John McDonagh (2015) [Journal of Environmental Management 157, 303-310].

    PubMed

    Azarnivand, Ali

    2015-12-01

    Wang et al. (2015) employed driving force-pressure-state-impact-response (DPSIR) framework to provide a robust decision-making structure for carbon emission reduction by use of wolfberry plantation in the Jingtai oasis, China. DPSIR appropriately identified the causes of problem along with adopting the responses to the barriers associated with wolfberry plantation. However, the discusser argues that, the paper could have prepared more viable outcomes, if the authors had used causal network rather than causal chains through the DPSIR framework. Furthermore, they could have quantified the mutual relationship among the relevant factors to provide a detailed economic assessment. With this knowledge in hand, the current discussion letter suggests eDPSIR and meDPSIR to address drawbacks regarding conventional DPSIR framework. Due to proper performance of eDPSIR and meDPSIR, they are recommended as practical tools in the future environmental studies. PMID:26355261

  8. Comment on “Magnetostratigraphic study of the Kuche Depression, Tarim Basin, and Cenozoic uplift of the Tian Shan Range, Western China” Baochun Huang, John D.A. Piper, Shoutao Peng, Tao Liu, Zhong Li, Qingchen Wang, Rixiang Zhu [Earth Planet. Sci. Lett., 2006, doi:10.1016/j.epsl.2006.09.020

    NASA Astrophysics Data System (ADS)

    Charreau, Julien; Chen, Yan; Gilder, Stuart; Barier, Laurie

    2008-04-01

    The recent publication of "Magnetostratigraphic study of the Kuche Depression, Tarim Basin, and Cenozoic uplift of the Tian Shan Range,Western China" by B.C. Huang, J.D.A. Piper, S.T. Peng, T. Liu, Z. Li, Q.C. Wang, R.X. Zhu [Earth Planet. Sci. Lett., 2006, doi:10.1016/j.epsl.2006.09.020] discusses the Cenozoic uplift history of the Tianshan Mountains by studying the magnetostratigraphy of Paleogene to Neogene continental sediments from two sections located in the Kuche basin at the northern edge of the Tarim basin. To support their conclusion they reinterpreted a magnetostratigraphic study of the Yaha section, which lies ~ 10 km south of their sections, we previously published [J. Charreau, S. Gilder, Y. Chen, S. Dominguez, J.-P. Avouac, S. Sen, M. Jolivet, Y. Li and W. Wang, Magnetostratigraphy of the Yaha section, Tarim Basin (China): 11 Ma acceleration in erosion and uplift of the Tianshan Mountains, Geology 34(3), 2006, 181­184.]. Here, (1) we argue that the interpretations of the sedimentation rate changes they proposed for the Kuche sections are partially invalid, (2) we disagree with their reinterpretation of the age of the Yaha section, and (3) we think that the way they interpret their AMS data is incorrect.

  9. SimHydro 2010: Hydraulic Modeling and Uncertainty, Sophia-Antipolis, 2-4 June 2010 -DeMarchi, C., Tao, W., Johengen, T.H., Stow, C.A.. -Uncertainty in Phosphorous Load Estimation from a Large Watershed in the Great Lakes Basin

    E-print Network

    in its watershed caused eutrophication of the bay. To improve this situation, a target Total Phosphorus of phosphorus output from point sources lead to diminishing eutrophication. However, eutrophication symptoms

  10. 4 | IEEE nanotEchnology magazInE | june 2015 1932-4510/152015IEEE taoRan lE, zIyIn lIn, c.P. Wong, anD m.m. tEntzERIS

    E-print Network

    Tentzeris, Manos

    -jet printing additive manufacturing technique in large areas for sensing ambient gases. These skins can to mass produce com- mercial devices at a low cost. INK-JET PRINTING: A NOVEL ADDITIVE MANUFACTURING layer on top of the substrate using etchants. in addition, milling machines are also used to realize

  11. A-site- and/or B-site-modified PbZrTiO3 materials and (Pb, Sr, Ca, Ba, Mg) (Zr, Ti, Nb, Ta)O3 films having utility in ferroelectric random access memories and high performance thin film microactuators

    NASA Technical Reports Server (NTRS)

    Roeder, Jeffrey F. (Inventor); Chen, Ing-Shin (Inventor); Bilodeau, Steven (Inventor); Baum, Thomas H. (Inventor)

    2001-01-01

    A modified PbZrTiO.sub.3 perovskite crystal material thin film, wherein the PbZrTiO.sub.3 perovskite crystal material includes crystal lattice A-sites and B-sites at least one of which is modified by the presence of a substituent selected from the group consisting of (i) A-site substituents consisting of Sr, Ca, Ba and Mg, and (ii) B-site substituents selected from the group consisting of Nb and Ta. The perovskite crystal thin film material may be formed by liquid delivery MOCVD from metalorganic precursors of the metal components of the thin film, to form PZT and PSZT, and other piezoelectric and ferroelectric thin film materials. The thin films of the invention have utility in non-volatile ferroelectric memory devices (NV-FeRAMs), and in microelectromechanical systems (MEMS) as sensor and/or actuator elements, e.g., high speed digital system actuators requiring low input power levels.

  12. 40 CFR Appendix III to Part 1068 - High-Altitude Counties

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...NEW MEXICO Bernalillo Catron Colfax Curry De Baca Grant Guadalupe Harding Hidalgo Lincoln Los Alamos Luna McKinley Mora Otero Rio Arriba Roosevelt Sandoval San Juan San Miguel Santa Fe Sierra Socorro Taos...

  13. Current 4/2014 Christopher Small

    E-print Network

    Small, Christopher

    Dust Project, Mapping dust storm source regions in the Gobi Desert, China w/ A. Taramelli, Q. Sun and W. Tao agriculture monitoring for index insurance validation w/ D. Osgood & M. Victor, 2-3/2009. Alashan Desert Win

  14. 78 FR 64005 - Notice of Public Meeting, Farmington District Resource Advisory Council Meeting, New Mexico

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ...; updates on ongoing planning efforts; Chaco Canyon leasing; the Mancos/Gallup Shale Resource Management... Cebolla Oil and Gas Lease Environmental Assessment; and Taos Field Office planning updates (including R...

  15. A Generic Tool Supporting Cache Design and Optimisation on Shared Memory Systems

    E-print Network

    Cintra, Marcelo

    as cache Dr. Jie Tao is now at the Institute for Scientific Computing, Forschungszentrum Karlsruhe, Hermann-von- Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany #12;size, line size). Further, programmers

  16. 78 FR 55075 - Radio Broadcasting Services; AM or FM Proposals To Change the Community of License

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-09

    ...20130724AGJ, From TAOS PUEBLO, NM, To SPRINGER, NM; GALAXY SYRACUSE LICENSEE LLC, Station WKRH, Facility ID 56996, BPH-20130708ABZ, From MINETTO, NY, To FAIR HAVEN, NY; GALAXY SYRACUSE LICENSEE LLC, Station WTKV, Facility ID...

  17. Geochemical associations and availability of cadmium (Cd) in a paddy field system, Northwestern Thailand 

    E-print Network

    Kosolsaksakul, Peerapat

    2014-11-27

    The Mae Tao watershed, northwestern Thailand, has become contaminated with cadmium (Cd) from the zinc mining activities area in the nearby Thanon-Thongchai mountains. Consumption of Cd-contaminated rice has led to ...

  18. Reverse Nearest Neighbor Search in Metric Spaces

    E-print Network

    Mamoulis, Nikos

    Reverse Nearest Neighbor Search in Metric Spaces Yufei Tao, Man Lung Yiu, and Nikos Mamoulis corresponds to their Euclidean dis- tance, the RNN query q (the black dot) returns p1 and p2. In particular, p

  19. The FASEB Journal Research Communication Hepatic signaling by the mechanistic target

    E-print Network

    Sabatini, David M.

    ,*,,,§, Tao Peng,*,,,§, ,2 Jonathan Ferreira,¶ Nicola Neretti,¶ Arthur Salomon,¶ David M. Sabatini., Demirkan, G., Boylan, J. M., Mihaylova, M. M., Peng, T., Ferreira, J., Neretti, N., Salomon, A., Sabatini

  20. NTT DoCoMo USA Labs, Inc. Copyright 2005-2006

    E-print Network

    Baeza-Yates, Ricardo

    TAO Reification points Meta level protocol Base level skeleton Dynamic Software Updates Michael Hicks, U Configurable Different devices, different functionality Runtime Updateable Replace software Runtime Upgradeable software management Innopath Bitfone Redbend mFormation Reflective middleware OpenORB, dynamic

  1. 76 FR 35935 - New Mexico Disaster #NM-00019 Declaration of Economic Injury

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ...Counties: Bernalillo, Lincoln, Taos. Contiguous Counties: New Mexico: Chaves, Cibola, Colfax, De Baca, Guadalupe, Mora, Otero, Rio Arriba, Sandoval, Santa Fe, Sierra, Socorro, Torrance, Valencia. Colorado: Conejos, Costilla. The...

  2. 40 CFR Appendix III to Part 1068 - High-Altitude Counties

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...Bernalillo Catron Colfax Curry De Baca Grant Guadalupe Harding Hidalgo Lincoln Los Alamos Luna McKinley Mora Otero Rio Arriba Roosevelt Sandoval San Juan San Miguel Santa Fe Sierra Socorro Taos Torrance Union...

  3. A Correlation Framework for the CORBA Component Model

    E-print Network

    Jung, Georg

    /TAO's real­time event­channel and in mission critical contexts such as Boeing's Bold Stroke avionics designed to support development of mission­control applications in the Boeing Bold Stroke framework. 1

  4. 78 FR 18783 - Establishment of the R[iacute]o Grande del Norte National Monument

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-28

    ...harsh landscape, the images carved into the gorge's dark basalt cliffs and the artifacts scattered across the forested slopes...world's major rift systems. Composed of Servilleta lava basalts and rhyolites, the Taos Plateau has long been a center...

  5. 78 FR 42976 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-International...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-18

    ...SC; Fraunhofer IZM, Berlin, GERMANY; Samsung Electro- Mechanics Co., LTD, Gyeonggi-Do, REPUBLIC OF KOREA; AT&S, Leoben...this venture. Also, Foxconn, Taipei Hsien, TAIWAN; and Quanta Computer, Tao Yuan Shine, TAIWAN, have withdrawn as...

  6. University of Illinois at Urbana-Champaign, 1304 W. Pennsylvania Ave., 338 AESB, Urbana, IL 61801 217.333.3570 abe.illinois.edu abe@illinois.edu

    E-print Network

    Lee, Tonghun

    . They will speak on Undergraduate Records. Hope to see you all there! Lawn Mower Winterization Dates Set The Ag the period designated. There is no grace period. Congratulations to all... Tao Lin - who passed his Final Ph

  7. Derivation of Newton's Law of Gravitation Based on a Fluid Mechanical Singularity Model of Particles

    E-print Network

    Xiao-Song Wang

    2006-10-25

    We speculate that the universe may be filled with a kind of fluid which may be called aether or tao. Thus, Newton's law of gravitation is derived by methods of hydrodynamics based on a sink flow model of particles.

  8. Combined L1 Trigger Tracker studies for HL-LHC upgrade 

    E-print Network

    Dimas Valle, Jose Roberto Roberto

    2014-09-24

    and for his successful leadership of the Undergraduate Research Scholars Program. Special thanks to Aysen Tatarinov, Sven Dildick and Tao Huang for all of their help during my research. 2 NOMENCLATURE LHC Large Hadron Collider HL LHC High Luminosity Large...

  9. Improving Effectiveness of Automated Software Testing in the Absence of Specifications

    E-print Network

    Xie, Tao

    Improving Effectiveness of Automated Software Testing in the Absence of Specifications Tao Xie Program specifications can be valuable in improving the effectiveness of automated software testing in generating test inputs and checking test executions for correctness. Un- fortunately, specifications

  10. Probing 3-ssDNA Loop Formation in E. coli RecBCD/RecBCDNA Complexes Using Non-natural

    E-print Network

    Lohman, Timothy M.

    for "Chi" Recognition Complexes C. Jason Wong1 , Rachel L. Rice1 , Nathan A. Baker1 , Tao Ju2 and Timothy M are a class of motor proteins that couple the energy from nucleoside triphosphate (NTP) binding and hydrolysis

  11. Bustin Laboratory

    Cancer.gov

    Protein Section, Laboratory of Metabolism Principal Investigator: Dr. Michael Bustin Staff Scientists: Dr. Yuri V. Postnikov Dr. Takashi Furusawa Research Associates: Dr. Mark Rochman Postdoctoral Associates: Dr. Eric Ciappio Dr. Tao Deng Dr. Jamie Kugler

  12. 75 FR 2889 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-International...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-19

    ...CHINA; Ibiden, Toshiba-cho, JAPAN; Pacific Insulating Material Co., Ltd., Shenzhen, PEOPLE'S REPUBLIC OF CHINA; Lenovo, Quarry Bay, HONG KONG- CHINA; and Quanta Computer Inc., Tao Yuan Shien, TAIWAN, have been added as parties to...

  13. Blood Impedance Characterization from Pulsatile Measurements School of Information Technology

    E-print Network

    Adler, Andy

    Blood Impedance Characterization from Pulsatile Measurements Tao Dai School of Information-Marquardt (LM) nonlinear curve fit- ting. Using the pulsatile impedance data, electrical properties of blood noise levels and sampling rates. Keywords--Bioimpedance spectroscopy; pulsatile impedance wave; Cole

  14. Nonstoichiometric control of tunnel-filling order, thermal expansion, and dielectric relaxation in tetragonal tungsten Bronzes Ba0.5-xTaO3-x.

    PubMed

    Pan, Fengjuan; Li, Xiaohui; Lu, Fengqi; Wang, Xiaoming; Cao, Jiang; Kuang, Xiaojun; Véron, Emmanuel; Porcher, Florence; Suchomel, Matthew R; Wang, Jing; Allix, Mathieu

    2015-09-21

    Ordering of interpolated Ba(2+) chains and alternate Ta-O rows (TaO)(3+) in the pentagonal tunnels of tetragonal tungsten bronzes (TTB) is controlled by the nonstoichiometry in the highly nonstoichiometric Ba0.5-xTaO3-x system. In Ba0.22TaO2.72, the filling of Ba(2+) and (TaO)(3+) groups is partially ordered along the ab-plane of the simple TTB structure, resulting in a ?2-type TTB superstructure (Pbmm), while in Ba0.175TaO2.675, the pentagonal tunnel filling is completely ordered along the b-axis of the simple TTB structure, leading to a triple TTB superstructure (P21212). Both superstructures show completely empty square tunnels favoring Ba(2+) conduction and feature unusual accommodation of Ta(5+) cations in the small triangular tunnels. In contrast with stoichiometric Ba6GaTa9O30, which shows linear thermal expansion of the cell parameters and monotonic decrease of permittivity with temperature within 100-800 K, these TTB superstructures and slightly nonstoichiometric simple TTB Ba0.4TaO2.9 display abnormally broad and frequency-dependent extrinsic dielectric relaxations in 10(3)-10(5) Hz above room temperature, a linear deviation of the c-axis thermal expansion around 600 K, and high dielectric permittivity ?60-95 at 1 MHz at room temperature. PMID:26347025

  15. Etiopathogenesis, clinical diagnosis and treatment of thromboangiitis obliterans – current practices

    PubMed Central

    Joviliano, Edwaldo Edner; Dellalibera-Joviliano, Renata; Dalio, Marcelo; Évora, Paulo RB; Piccinato, Carlos E

    2009-01-01

    Thromboangiitis obliterans (TAO) is a segmental inflammatory occlusive disorder that affects small- and medium-sized arteries, and arm and leg veins of young smokers. Several different diagnostic criteria have been offered for the diagnosis of TAO. Clinically, it manifests as migratory thrombophlebitis or signs of arterial insufficiency in the extremities. It is characterized by highly cellular and inflammatory occlusive thrombi, primarily of the distal extremities. Thromboses are often occlusive and sometimes display moderate, nonspecific inflammatory infiltrate, consisting mostly of polymorphonuclear leukocytes, mononuclear cells and rare multinuclear giant cells. The immune system appears to play a critical role in the etiology of TAO. However, knowledge about immunological aspects involved in the progression of vascular tissue inflammation, and consequently, the evolution of this disease, is still limited. There are several studies that suggest the involvement of genetic factors and results have shown increasing levels of antiendothelial cell antibodies in patients with active disease. Vasodilation is impaired in patients with TAO. TAO disorder may actually be an autoimmune disorder, probably initiated by an unknown antigen in the vascular endothelium, possibly a component of nicotine. There are various therapies available for treatment of TAO, but the major and indispensable measure is smoking cessation. Except for discontinuation of tobacco use, no forms of therapy are definitive. Sympathectomy, cilostazol and prostaglandin analogues (prostacyclin or prostaglandin E) have been used in specific conditions. Recently, therapeutic angiogenesis with autologous transplantation of bone marrow mononuclear cells has been studied in patients with critical limb ischemia. PMID:22477511

  16. Identification and partial purification of a stage-specific 33 kDa mitochondrial protein as the alternative oxidase of the Trypanosoma brucei brucei bloodstream trypomastigotes.

    PubMed

    Chaudhuri, M; Ajayi, W; Temple, S; Hill, G C

    1995-01-01

    The glycerophosphate oxidase (GPO), the unique terminal oxidase of bloodstream trypanosome (TAO), appears to be functionally similar to the alternative oxidases of some plants and higher fungi. Immunoblotting of mitochondrial proteins of bloodstream trypomastigotes of Trypanosoma brucei with monoclonal or polyclonal antibodies to Sauromatum guttatum (voodoo lily) and Symplocarpus foetidus (skunk cabbage) alternative oxidases respectively revealed two proteins of about 33 kDa (p33) and 68 kDa (p68). These proteins are not present in procyclic trypomastigotes. Electrophoresis under rigorous denaturing conditions indicated p68 to be the dimer of p33. Indirect immunofluorescent studies of bloodstream and procyclic trypomastigotes with monoclonal antibody to plant alternative oxidase also showed the localization of 33 kDa protein in the mitochondria of the bloodstream trypomastigotes. The functional TAO activity could be solubilized efficiently from the mitochondrial membrane of the bloodstream trypomastigotes by 1% NP-40 or 10 mM lauryl maltoside. When fractionated by Superose 12 gel filtration chromatography, p33 was co-purified with the TAO enzymatic activity. The apparent molecular size of the active enzyme complex was found to be 160 kDa. Gradual disappearance of the 33 kDa protein and the TAO enzymatic activity were well correlated during in vitro differentiation of the bloodstream to procyclic trypomastigotes. This study implies that the net biosynthesis of p33, an essential subunit of TAO, is decreased during differentiation from bloodstream to procyclic trypomastigotes. PMID:7581322

  17. The differential diagnosis and classification of eyelid retraction.

    PubMed Central

    Bartley, G B

    1995-01-01

    PURPOSE: Classification schemes are useful in the formulation of differential diagnoses. Thoughtful commentary has been devoted to the classification of blepharoptosis, but the causes of eyelid retraction have received less attention in published reports. Although eyelid retraction most frequently is associated with Graves' ophthalmopathy, numerous other entities may cause the sign. This study was undertaken to provide a more comprehensive differential diagnosis and classification of eyelid retraction. METHODS: A series of patients with eyelid retraction was studied, and pertinent published reports were reviewed. RESULTS: Forty-four patients with different causes for eyelid retraction are described. Normal thyroid function and regulation were confirmed in all patients in whom Graves' ophthalmopathy could not be excluded by clinical, biochemical, or historical criteria. CONCLUSION: Based on a series of patients and reported cases, a differential diagnosis for eyelid retraction is proposed using a classification system comprising three categories (neurogenic, myogenic, and mechanistic). Images FIGURE 1 FIGURE 2 FIGURE 3 A FIGURE 3 B FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7 A FIGURE 7 B FIGURE 7 C FIGURE 7 D FIGURE 7 E FIGURE 8 FIGURE 9 FIGURE 10 A FIGURE 10 B FIGURE 10 C FIGURE 11 A FIGURE 11 B PMID:8719687

  18. Surgical treatment of hyperthyroidism: a ten-year experience.

    PubMed

    Werga-Kjellman, P; Zedenius, J; Tallstedt, L; Träisk, F; Lundell, G; Wallin, G

    2001-02-01

    Hyperthyroidism is treated either by antithyroid drugs, radioiodine (I131) or surgery. In Sweden, surgery is often performed in patients with large goiter or severe hyperthyroidism with infiltrative endocrine ophthalmopathy. To evaluate indications and results of surgical treatment, data from 380 patients operated on for hyperthyroidism at our department during 1986-1995 were analyzed. Twenty-six percent were referred for surgery because of failure of treatment with antithyroid drugs or I131. Ninety-one percent were subjected to subtotal thyroidectomy with a median remnant weight of less than 2 g. In the remaining patients, total thyroidectomy was performed. Transient vocal cord affection occurred in 2.6%, none of which was permanent. Prolonged postoperative hypocalcemia occurred in 3.1%, and permanent hypoparathyroidism in 1%. There was no difference in complication rate between subtotal or total thyroidectomy. In patients with Graves' disease, 5% worsened with regard to ophthalmopathy initially after surgery but later improved. Recurrent disease occurred in 2% of the patients, all of whom had undergone subtotal thyroidectomy. Surgery is not first-line therapy in all patients with hyperthyroidism. However, in experienced hands, surgery is a good therapeutic alternative that can be carried out with no mortality, few complications, and, provided that a minimal remnant is left, very few recurrences. PMID:11288990

  19. The role of oxidative stress on the pathogenesis of graves' disease.

    PubMed

    Zarkovi?, Miloš

    2012-01-01

    Graves' disease is a most common cause of hyperthyroidism. It is an autoimmune disease, and autoimmune process induces an inflammatory reaction, and reactive oxygen species (ROSs) are among its products. When balance between oxidants and antioxidants is disturbed, in favour of the oxidants it is termed "oxidative stress" (OS). Increased OS characterizes Graves' disease. It seems that the level of OS is increased in subjects with Graves' ophthalmopathy compared to the other subjects with Graves' disease. Among the other factors, OS is involved in proliferation of orbital fibroblasts. Polymorphism of the 8-oxoG DNA N-glycosylase 1 (hOGG1) involved in repair of the oxidative damaged DNA increases in the risk for developing Grave's disease. Treatment with glucocorticoids reduces levels of OS markers. A recent large clinical trial evaluated effect of selenium on mild Graves' ophthalmopathy. Selenium treatment was associated with an improved quality of life and less eye involvement and slowed the progression of Graves' orbitopathy, compared to placebo. PMID:22175033

  20. Experimental and analytical study of thermal acoustic oscillations. [in the transfer and storage of cryogens

    NASA Technical Reports Server (NTRS)

    Spradley, L. W.; Dean, W. G.; Karu, Z. S.

    1976-01-01

    The thermal acoustic oscillations (TAO) data base was expanded by running a large number of tubes over a wide range of parameters known to affect the TAO phenomenon. These parameters include tube length, wall thickness, diameter, material, insertion length and length-to-diameter ratio. Emphasis was placed on getting good boiloff data. A large quantity of data was obtained, reduced, correlated and analyzed and is presented. Also presented are comparisons with previous types of correlations. These comparisons show that the boiloff data did not correlate with intensity. The data did correlate in the form used by Rott, that is boiloff versus TAO pressure squared times frequency to the one-half power. However, this latter correlation required a different set of correlation constants, slope and intercept, for each tube tested.

  1. Aerobic Biotransformation of Fluorotelomer Thioether Amido Sulfonate (Lodyne) in AFFF-Amended Microcosms.

    PubMed

    Harding-Marjanovic, Katie C; Houtz, Erika F; Yi, Shan; Field, Jennifer A; Sedlak, David L; Alvarez-Cohen, Lisa

    2015-07-01

    The aerobic biotransformation pathways of 4:2, 6:2, and 8:2 fluorotelomer thioether amido sulfonate (FtTAoS) were characterized by determining the fate of the compounds in soil and medium microcosms amended with an aqueous film-forming foam (AFFF) solution. The biotransformation of FtTAoS occurred in live microcosms over approximately 40 days and produced 4:2, 6:2, and 8:2 fluorotelomer sulfonate (FtS), 6:2 fluorotelomer unsaturated carboxylic acid (FtUCA), 5:3 fluorotelomer carboxylic acid (FtCA), and C4 to C8 perfluorinated carboxylic acids (PFCAs). Two biotransformation products corresponding to singly and doubly oxygenated forms of 6:2 FtTAoS were also identified through high resolution mass spectrometry (MS) analysis and liquid chromatography tandem-MS. An oxidative assay was used to indirectly quantify the total concentration of polyfluorinated compounds and check the mass balance. The assay produced near complete mass recovery of FtTAoS after biotransformation, with 10% (mol/mol) of the amended FtTAoS accounted for in FtS, FtCA, and PFCA products. The transformation rates of identified products appear to be slow relative to FtTAoS, indicating that some intermediates may persist in the environment. This study confirms some of the sources of FtS and PFCAs in groundwater and soil at AFFF-impacted sites and suggests that fluorinated intermediates that are not routinely measured during the biotransformation of PFASs may accumulate. PMID:26042823

  2. Isolation of a Gene Responsible for the Oxidation of trans-Anethole to para-Anisaldehyde by Pseudomonas putida JYR-1 and Its Expression in Escherichia coli

    PubMed Central

    Han, Dongfei; Ryu, Ji-Young; Kanaly, Robert A.

    2012-01-01

    A plasmid, pTA163, in Escherichia coli contained an approximately 34-kb gene fragment from Pseudomonas putida JYR-1 that included the genes responsible for the metabolism of trans-anethole to protocatechuic acid. Three Tn5-disrupted open reading frame 10 (ORF 10) mutants of plasmid pTA163 lost their abilities to catalyze trans-anethole. Heterologously expressed ORF 10 (1,047 nucleotides [nt]) under a T7 promoter in E. coli catalyzed oxidative cleavage of a propenyl group of trans-anethole to an aldehyde group, resulting in the production of para-anisaldehyde, and this gene was designated tao (trans-anethole oxygenase). The deduced amino acid sequence of TAO had the highest identity (34%) to a hypothetical protein of Agrobacterium vitis S4 and likely contained a flavin-binding site. Preferred incorporation of an oxygen molecule from water into p-anisaldehyde using 18O-labeling experiments indicated stereo preference of TAO for hydrolysis of the epoxide group. Interestingly, unlike the narrow substrate range of isoeugenol monooxygenase from Pseudomonas putida IE27 and Pseudomonas nitroreducens Jin1, TAO from P. putida JYR-1 catalyzed isoeugenol, O-methyl isoeugenol, and isosafrole, all of which contain the 2-propenyl functional group on the aromatic ring structure. Addition of NAD(P)H to the ultrafiltered cell extracts of E. coli (pTA163) increased the activity of TAO. Due to the relaxed substrate range of TAO, it may be utilized for the production of various fragrance compounds from plant phenylpropanoids in the future. PMID:22610435

  3. Structure of finite nilspaces and inverse theorems for the Gowers norms in bounded exponent groups

    E-print Network

    Szegedy, Balazs

    2010-01-01

    A result of the author shows that the behavior of Gowers norms on bounded exponent abelian groups is connected to finite nilspaces. Motivated by this, we investigate the structure of finite nilspaces. As an application we prove inverse theorems for the Gowers norms on bounded exponent abelian groups. It says roughly speaking that if a function on A has non negligible U(k+1)-norm then it correlates with a phase polynomial of degree k when lifted to some abelian group extension of A. This result is closely related to a conjecture by Tao and Ziegler. In prticular we obtain a new proof for the Tao-Ziegler inverse theorem.

  4. Structural and electronic investigations of PbTa4O11 and BiTa7O19 constructed from ?-U3O8 types of layers

    NASA Astrophysics Data System (ADS)

    Boltersdorf, Jonathan; Maggard, Paul A.

    2015-09-01

    The PbTa4O11 and BiTa7O19 phases were prepared by ion-exchange and solid-state methods, respectively, and their structures were characterized by neutron time-of-flight diffraction and Rietveld refinement methods (PbTa4O11, R 3 (No. 146), a=6.23700(2) Å, c=36.8613(1) Å; BiTa7O19, P 6 bar c 2 (No. 188), a=6.2197(2) Å, c=20.02981(9) Å). Their structures are comprised of layers of TaO6 octahedra surrounded by three 7-coordinate Pb(II) cations or two 8-coordinate Bi(III) cations. These layers alternate down the c-axis with ?-U3O8 types of single and double TaO7 pentagonal bipyramid layers. In contrast to earlier studies, both phases are found to crystallize in noncentrosymmetric structures. Symmetry-lowering structural distortions within PbTa4O11, i.e. R 3 bar c ?R3, are found to be a result of the displacement of the Ta atoms within the TaO7 and TaO6 polyhedra, towards the apical and facial oxygen atoms, respectively. In BiTa7O19, relatively lower reaction temperatures leads to an ordering of the Bi/Ta cations within a lower-symmetry structure, i.e., P63/mcm? P 6 bar c 2 . In the absence of Bi/Ta site disorder, the Ta-O-Ta bond angles decrease and the Ta-O bond distances increase within the TaO7 double layers. Scanning electron microscopy images reveal two particle morphologies for PbTa4O11, hexagonal rods and finer irregularly-shaped particles, while BiTa7O19 forms as aggregates of irregularly-shaped particles. Electronic-structure calculations confirm the highest-energy valence band states are comprised of O 2p-orbitals and the respective Pb 6s-orbital and Bi 6s-orbital contributions. The lowest-energy conduction band states are composed of Ta 5d-orbital contributions that are delocalized over the TaO6 octahedra and layers of TaO7 pentagonal bipyramids. The symmetry-lowering distortions in the PbTa4O11 structure, and the resulting effects on its electronic structure, lead to its relatively higher photocatalytic activity compared to similar structures without these distortions.

  5. Numerical Modeling of Fracture Permeability Change in Naturally Fractured Reservoirs Using a Fully Coupled Displacement Discontinuity Method. 

    E-print Network

    Tao, Qingfeng

    2010-07-14

    -Chairs of Committee, Christine A. Ehlig-Economides Ahmad Ghassemi Committee Members, A. Daniel Hill Ding Zhu Yalchin Efendiev.... (May 2010) Qingfeng Tao, B.S., China University of Geosciences; M.S., University of North Dakota Co-Chairs of Advisory Committee: Dr. Christine A. Ehlig-Economides Dr. Ahmad Ghassemi Fractures are the main flow channels in naturally fractured...

  6. ION GNSS 2011, Session C6, Portland, OR, 20-23 September 2011 page 1 of 8 Implementation of a Navigation Domain GNSS

    E-print Network

    Calgary, University of

    of a Navigation Domain GNSS Signal Tracking Loop Tao Lin, James T. Curran, Cillian O'Driscoll and Gérard Lachapelle Position Location And Navigation Group Department of Geomatics Engineering Schulich School processing, satellite-based navigation, inertial navigation and ground-based wireless location. Dr. James T

  7. Brief Communications Dissociating the Detection of Intentionality from Animacy in

    E-print Network

    Scholl, Brian

    Posterior Superior Temporal Sulcus Tao Gao, Brian J. Scholl, and Gregory McCarthy Department of Psychology in temporoparietal cortex, including areas in and near the (predominantly right) posterior superior temporal sulcus sulcus (pSTS) and angular gyrus, particularly in the right hemisphere (Castelli et al., 2000; Blakemore

  8. Software Analytics in Practice Dongmei Zhang, Shi Han, Yingnong Dang, Jian-Guang Lou, Haidong Zhang, Microsoft Research Asia,

    E-print Network

    Xie, Tao

    Software Analytics in Practice Dongmei Zhang, Shi Han, Yingnong Dang, Jian-Guang Lou, Haidong Zhang, Microsoft Research Asia, China Tao Xie, University of Illinois at Urbana-Champaign, USA Abstract: Software analytics is to utilize data-driven approaches to enable software practitioners to perform data exploration

  9. Atmos. Chem. Phys., 15, 86958715, 2015 www.atmos-chem-phys.net/15/8695/2015/

    E-print Network

    Meskhidze, Nicholas

    on the composition of the stratosphere M. Tao1, P. Konopka1, F. Ploeger1, J.-U. Grooß1, R. Müller1, C. M. Volk2, K. A; Orsolini et al., 1997; Edouard et al., 1996; Konopka et al., 2003). However, resolving these struc- tures; Konopka et al., 2003, 20

  10. Proceedings of Student-Faculty Research Day, CSIS, Pace University, May 3rd A Semantic Approach to Intelligent and Adaptive Learning Based

    E-print Network

    Tappert, Charles

    , Artifical Intelligence, Learning Objects, Knowledge Representation, Adaptive Learning, Inteligent Tutoring Approach to Intelligent and Adaptive Learning Based on Web Learning Objects Maria Sette and Lixin Tao Pace--Tutoring systems are computer-based learning systems. In order to be "intelligent" they must present "human- like

  11. Physica A ( ) Contents lists available at SciVerse ScienceDirect

    E-print Network

    Serota, Rostislav

    .elsevier.com/locate/physa Distribution of wealth in a network model of the economy Tao Maa , John G. Holdenb , R.A. Serotaa, a Department, analytically and numerically, that wealth distribution in the Bouchaud­Mézard network model of the economy research [1]. Here, we study a network model of the economy proposed by Bouchaud and Mézard (BM) [2

  12. Elsevier Editorial System(tm) for Expert Systems With Applications Manuscript Draft

    E-print Network

    Cao, Longbing

    of a protein's 3D structure based on its amino acid sequence information. Proteins are said to have a common classifier; Amino acid sequence Corresponding Author: Dr Tao Yang, Corresponding Author's Institution: First, and multiple heterogeneous feature groups derived from different propensities of amino acids. This raises

  13. A study of the effect of boundary conditions and drag force on the diffusion of a Newtonian fluid through a non-linearly elastic solid 

    E-print Network

    Prasad, Sharat Chand

    2002-01-01

    with the experiments (whether it is the saturation boundary condition used by Rajagopal, Wineman and Gandhi, the traction splitting boundary condition used by Rajagopal and Tao, the natural boundary condition used by Baek and Srinivasa, or the fact that the chemical...

  14. In-Situ Hydrothermal Growth of Bi-Hierarchical ZnO Nanoarchitecture with Surface Modification for Efficient Hybrid Solar Cells

    E-print Network

    Cao, Guozhong

    boosting the ultimate photoelectric conversion efficiency of organic-inorganic hybrid solar cells (HSCs for Efficient Hybrid Solar Cells Yan-Zhen Zheng a,b , Haiyang Ding c , Yu Liu a , Xia Tao a, *, Guozhong Cao d-inorganic hybrid solar cells dye surface modification hierarchical zinc oxide nanoarchitecture one-dimension A B

  15. Breaking H2 -MAC Using Birthday Paradox

    E-print Network

    International Association for Cryptologic Research (IACR)

    Breaking H2 -MAC Using Birthday Paradox Fanbao Liu1,2 , Tao Xie1 and Changxiang Shen2 1 School of Computer, Beijing University of Technology, 100124, Beijing, P. R. China liufanbao@gmail.com Abstract. H2 and security of HMAC at the same time. However, as pointed out by the designer, the security of H2 -MAC also

  16. ON FALCONER'S DISTANCE SET CONJECTURE M. BURAK ERDO~GAN

    E-print Network

    Erdogan, Mehmet

    ON FALCONER'S DISTANCE SET CONJECTURE M. BURAK ERDO~GAN Abstract. In this paper, using a recent parabolic restriction estimate of Tao, we obtain improved partial results in the direction of Falconer] and [13]. Falconer's conjecture [8] is a variant of Erd¨os' conjecture: Conjecture. Let d 2. Let E

  17. Opportunistic Source Coding for Data Gathering in Wireless Sensor Networks

    E-print Network

    1 Opportunistic Source Coding for Data Gathering in Wireless Sensor Networks Tao Cui, Lijun Chen capacity of multihop wireless networks, an important topic addressed by wireless sensor networks community for correlated data gathering in wireless sensor networks, which ex- ploits the broadcast nature of wireless

  18. Cultural Issues of School Dropouts in Hong Kong

    ERIC Educational Resources Information Center

    Lau, Yuk King; Tsang, Bill Y. P.; Kwok, Diana K.

    2007-01-01

    Despite the 150 years of British colonial governance in Hong Kong, Chinese collectivist culture continues to be a dominant source of influence in the learning context of students (Cheng, 1998; Salili, Lai and Leung, 2004; Tao and Hong, 2000), placing a great emphasis on education and effort (Salili and Lai, 2003). Education is viewed as the…

  19. How to Manage the Chinese Coal Value Chain by Kevin Jianjun Tu

    E-print Network

    Change Strategy and International Cooperation of the NDRC, Yang Ailun and Hu Tao at the World Resources at the World Coal Association, Casey Delhotal, Robert Marley and Scott Smouse at the U.S. DOE, Dan Guttman produced 3.66 billion tonnes of coal, near half of global total. Railway is the most important mode of coal

  20. The mechanism by which influenza A virus nucleoprotein forms oligomers and binds RNA

    E-print Network

    Tao, Yizhi Jane

    health, particularly the currently circulating avian H5N1 viruses. The influenza viral nucleoproteinLETTERS The mechanism by which influenza A virus nucleoprotein forms oligomers and binds RNA Qiaozhen Ye1 , Robert M. Krug2 & Yizhi Jane Tao1 Influenza A viruses pose a serious threat to world public

  1. A Global Map of p53 Transcription-Factor Binding Sites in the Human Genome

    E-print Network

    Weng, Zhiping

    Qiang Wu,1 Vinsensius B. Vega,1 Kuo Ping Chiu,1 Patrick Ng,1 Tao Zhang,1 Atif Shahab,2 How Choong Yong,2 as a readout to define p53 binding loci with remarkable specificity. Based on this information, we refined

  2. A Robust Collaborative Filtering Algorithm Using Ordered Logistic Regression

    E-print Network

    Baras, John S.

    A Robust Collaborative Filtering Algorithm Using Ordered Logistic Regression Shanshan Zheng, Tao filtering algorithm, which is based on ordered logistic regression and takes into account both similarities algorithm based on ordered logistic regression and consider both the similarities among the users

  3. SANDRA J. LINDOW Menomonie, WI 54751

    E-print Network

    Wu, Mingshen

    of Science Fiction and Fantasy, McFarland, 2013. Dancing the Tao: Le Guin and Moral Development, Cambridge, 2008. "Eleanor Arnason" and "Joan Slonczewski" in Women in Science Fiction and Fantasy, ed. Robin Reed York: Oxford UP, 2006. Book Reviews for Kaleidoscope, SF Studies, New York Review of Science Fiction

  4. Brittle film-induced cracking of ductile substrates , Lijie Qiao a,

    E-print Network

    Volinsky, Alex A.

    Brittle film-induced cracking of ductile substrates Tao Guo a , Lijie Qiao a, , Xiaolu Pang b 29 May 2015 Revised 22 July 2015 Accepted 23 July 2015 Keywords: Brittle film Ductile substrate Film-induced cracking Dislocations Crack velocity a b s t r a c t Film and substrate mechanical integrity is essential

  5. Targets for early discoveries at the LHC

    E-print Network

    Targets for early discoveries at the LHC Lian-Tao Wang University of Chicago 04/11/2011 Monday to emphasize less "well-known" or less "well-mentioned" but not "strange" channels. In the next year or so, LHC

  6. ON THE PIECEWISELY SMOOTH SOLUTIONS TO NONHOMOGENEOUS SCALAR CONSERVATION LAWS*

    E-print Network

    ON THE PIECEWISELY SMOOTH SOLUTIONS TO NON­HOMOGENEOUS SCALAR CONSERVATION LAWS* YAN­XIANG KAN y , TAO TANG z AND ZHEN­HUAN TENG y Abstract. We study the structure and smoothness of non­homogeneous convex conser­ vation laws. The question regarding the number of smoothness pieces is addressed

  7. Quantized plasmon quenching dips

    E-print Network

    Cai, Long

    Quantized plasmon quenching dips nanospectroscopy via plasmon resonance energy transfer Gang Logan Liu1­4, Yi-Tao Long1,4, Yeonho Choi1, Taewook Kang1 & Luke P Lee1,2 We observed quantized plasmon quenching dips in resonant Rayleigh scattering spectra by plasmon resonance energy transfer (PRET) from

  8. Theoretical study on low dielectric loss perovskites Ba(Zn1/3Ta2/3)O3 by first-principles calculations

    NASA Astrophysics Data System (ADS)

    Honda, Atsushi; Higai, Shin'ichi; Kageyama, Keisuke; Higuchi, Yukio; Shiratsuyu, Kosuke

    2015-10-01

    We performed first-principles theoretical calculations on microwave dielectric compounds Ba(Zn1/3Ta2/3)O3, to clarify the origin of high Q characteristics in the Zn/Ta ordered structure. It was found that Zn atoms suppress the intrinsic ferroelectric nature of Slater mode vibration in TaO6 octahedra. This results in the improvement of harmonicity in lattice vibration. There are two important mechanisms. One is the compression of TaO6 octahedra by adjacent ZnO6, and then the double-well potential that TaO6 originally has is narrowed to be single-well with higher harmonicity. The other is the weakening of the covalent character of Ta-O bonds by adjacent Zn atoms, which is the origin of the double-well potential. In the fully ordered Ba(Zn1/3Ta2/3)O3, all Ta atoms are adjacent to Zn atoms, where Zn atoms have the maximum effect on improving harmonicity. Thus, highly ordered Ba(Zn1/3Ta2/3)O3 with prolonged heat treatment exhibits a high Q value.

  9. Curing the Medical Manpower Shortage

    ERIC Educational Resources Information Center

    Murphy, Betty

    1973-01-01

    The OEO-funded Sangre de Cristo Comprehensive Health System in Costilla and Conejos Counties, Colorado, and northern Taos County, New Mexico, utilizes medical practitioners who are certified to practice a variety of medical techniques under the supervision of licensed physicians. (JM)

  10. Thinking in C++ 2nd Volume 2: Standard Libraries &

    E-print Network

    Sherrill, David

    to date." Al Stevens Contributing Editor, Doctor Dobbs Journal "Eckel's book is the only one to so clearly Author, The Tao of Objects "Thinking in C++ patiently and methodically explores the issues of when in the examples and text of this book are fictional; any relationship to persons living or dead or to fictional

  11. Multicolor Fluorescent Biosensor for Multiplexed Detection of DNA Rong Hu,,,

    E-print Network

    Tan, Weihong

    Multicolor Fluorescent Biosensor for Multiplexed Detection of DNA Rong Hu,,,§ Tao Liu,,§ Xiao the visible to NIR region. This broad-spectrum quencher was then adopted to develop a multicolor biosensor via exhibits a very high quenching efficiency on all ssDNA-labeled dyes associated with biosensor detection

  12. Impact of aerosols and atmospheric thermodynamics on cloud properties within the climate system

    E-print Network

    Masunaga, Hirohiko

    Toshihisa Matsui, Hirohiko Masunaga, and Roger A. Pielke Sr. Department of Atmospheric Science, Colorado, T., H. Masunaga, R. A. Pielke Sr., and W.-K. Tao (2004), Impact of aerosols and atmospheric (mb) pressure level [Klein and Hartmann, 1993]. Klein and Hartmann [1993] demonstrate that high LTSS

  13. Feng, Cheong and Shu, Effects of Abstraction for Biomimetic Design MD14-1084, Page 1 of 11 To appear in: Special Issue on Biologically Inspired Design

    E-print Network

    Shu, Lily H.

    Feng, Cheong and Shu, Effects of Abstraction for Biomimetic Design MD14-1084, Page 1 of 11 FOR BIOMIMETIC DESIGN Tao Feng, Hyunmin Cheong, L.H. Shu* Dept. of Mechanical & Industrial Engineering University of much biological knowledge, beyond databases created for biomimetic design. However, designers may need

  14. Proceedings of COLING 2014, the 25th International Conference on Computational Linguistics: Technical Papers, pages 827836, Dublin, Ireland, August 23-29 2014.

    E-print Network

    ) of the American Cancer Society. We analyze user messages of CSN to identify the two most important types of social of an online cancer support community, Cancer Survivors Network (CSN), to identity the two types of socialCoursiere, 2001; Beaudoin and Tao, 2007). When people suffering from a serious disease such as cancer or AIDS

  15. Remarkable charge-trapping efficiency of the memory device with (TiO{sub 2}){sub 0.8}(Al{sub 2}O{sub 3}){sub 0.1} composite charge-storage dielectric

    SciTech Connect

    Jiang, K.; Ou, X.; Cao, Z. Y.; Liu, X. J.; Lu, W.; Xu, B.; Li, A. D.; Xia, Y. D.; Yin, J. Liu, Z. G.; Lan, X. X.; Gong, C. J.

    2014-06-30

    A memory device p-Si/SiO{sub 2}/(TiO{sub 2}){sub 0.8}(Al{sub 2}O{sub 3}){sub 0.1}(TAO-81)/Al{sub 2}O{sub 3}/Pt was fabricated, in which a composite of two high-k dielectrics with a thickness of 1?nm was employed as the charge-trapping layer to enhance the charge-trapping efficiency of the memory device. At an applied gate voltage of ±9?V, TAO-81 memory device shows a memory window of 8.83?V in its C-V curve. It also shows a fast response to a short voltage pulse of 10{sup ?5}?s. The charge-trapping capability, the endurance, and retention characteristics of TAO-81 memory device can be improved by introducing double TAO-81 charge-trapping layers intercalated by an Al{sub 2}O{sub 3} layer. The charge-trapping mechanism in the memory device is mainly ascribed to the generation of the electron-occupied defect level in the band gap of Al{sub 2}O{sub 3} induced by the inter-diffusion between TiO{sub 2} and Al{sub 2}O{sub 3}.

  16. 2044 Chinese Science Bulletin Vol. 45 No. 22 November 2000 Protein functional-group 3D motif and its applications

    E-print Network

    Ye, Yuzhen

    2044 Chinese Science Bulletin Vol. 45 No. 22 November 2000 Protein functional-group 3D motif and its applications YE Yuzhen, XIE Tao & DING Dafu Shanghai Institute of Biochemistry, Chinese Academy is more sensitive for protein function prediction. #12;NOTES Chinese Science Bulletin Vol. 45 No. 22

  17. Numerical Study of Flexible Flapping Wing Propulsion and Mingjun Wei

    E-print Network

    Wei, Mingjun

    THE fact that birds and insects use flapping wings to generate lift and thrust has inspired the earliestNumerical Study of Flexible Flapping Wing Propulsion Tao Yang and Mingjun Wei New Mexico State highly flexible flapping wings interacting with fluid flows. Here, the fluid motion, solid motion

  18. A Global Approach for Reduced-Order Models of Flapping Flexible Wings

    E-print Network

    Wei, Mingjun

    human history, though many attempts were made to fly like a bird using flapping wings, none of them were provided by engines and the lift provided by fixed wings, which led to a great success of modern airplanesA Global Approach for Reduced-Order Models of Flapping Flexible Wings Mingjun Wei , Tao Yang New

  19. DeepSentiBank: Visual Sentiment Concept Classification with Deep Convolutional Neural Networks

    E-print Network

    Chang, Shih-Fu

    DeepSentiBank: Visual Sentiment Concept Classification with Deep Convolutional Neural Networks Tao the classifiers of the concepts. We adopt the popular model of deep convolutional neural networks which recently, Krizhevsky et al. [18] show deep convolutional neural networks (CNNs) is able to achieve great classification

  20. End-to-End Text Recognition with Convolutional Neural Networks David J. Wu

    E-print Network

    Boneh, Dan

    End-to-End Text Recognition with Convolutional Neural Networks Tao Wang David J. Wu Adam Coates a different route and com- bine the representational power of large, multilayer neural networks together knowledge. We integrate these learned features into a large, discriminatively-trained convolutional neural

  1. Educational Software Engineering: Where Software Engineering, Education, and Gaming Meet

    E-print Network

    Xie, Tao

    Educational Software Engineering: Where Software Engineering, Education, and Gaming Meet Tao Xie and advocate the subfield of educational software engineering (i.e., software engineering for education), which develops software engineering technologies (e.g., software testing and analysis, software analytics

  2. 75 FR 53280 - Environmental Management Site-Specific Advisory Board, Northern New Mexico

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-31

    ... Environmental Management Site-Specific Advisory Board, Northern New Mexico AGENCY: Department of Energy. ACTION...-Specific Advisory Board (EM SSAB), Northern New Mexico. The Federal Advisory Committee Act (Pub. L. 92-463... Pueblo Sur, Taos, New Mexico 87571. FOR FURTHER INFORMATION CONTACT: Menice Santistevan, Northern...

  3. Electrostatic Regulation of Genome Packaging in Human Hepatitis B Virus Zhen-Gang Wang,

    E-print Network

    Wu, Jianzhong

    Electrostatic Regulation of Genome Packaging in Human Hepatitis B Virus Tao Jiang, Zhen-Gang Wang, California ABSTRACT Hepatitis B virus (HBV) is a contagious human pathogen causing liver diseases-termini. INTRODUCTION Hepatitis B virus (HBV) is a pararetrovirus responsible for up to 80% of all cases

  4. IEEE SIGNAL PROCESSING LETTERS, VOL. 19, NO. 8, AUGUST 2012 503 Direction-of-Arrival Estimation of Hydroacoustic

    E-print Network

    Nehorai, Arye

    -band mixed signals. Note that though similar procedures of estimation performance analysis and comparison of Hydroacoustic Signals From Marine Vessels Containing Random and Sinusoidal Components Tao Li and Arye Nehorai of hydroacoustic signals from marine vessels, which contain both random and sinusoidal components. We generalize

  5. Killing Mosquitoes and Keeping Practice: Teacher Education as Sustaining Paradox

    ERIC Educational Resources Information Center

    Keiser, David Lee

    2013-01-01

    The moral and ethical charge of teaching and teacher education includes sustaining equanimity and paradox, and maintaining poise amongst contradicting policies and interests. This paper draws upon the wisdom of the Tao Te Ching to address some paradoxes in education and teacher preparation. Specifically, the article looks at four chapters of the…

  6. POLAR: Placement based on Novel Rough Legalization and Refinement

    E-print Network

    Chu, Chris C.-N.

    POLAR: Placement based on Novel Rough Legalization and Refinement Tao Lin 1 , Chris Chu 1 , Joseph}@iastate.edu, {joseph_shinnerl, ismail_bustany, ivailo_nedelchev}@mentor.com Abstract--A new quadratic global placer-linear scaling. In ComPLx [8], the entire placement process is modelled by subgradient primal-dual Lagrange

  7. On the regularity of approximate solutions to conservation laws with piecewise smooth solutions

    E-print Network

    or more general approximations to scalar conservation laws. The methods of analysis include matching­functional method, see e.g. Kuznetsov [7]; and energy­like methods, see e.g. Tadmor & Tang [18]. The resultsOn the regularity of approximate solutions to conservation laws with piecewise smooth solutions Tao

  8. Exploring the Potential for High-Quality Epitaxial CdTe Solar Cells , Ana Kanevce2

    E-print Network

    Sites, James R.

    Exploring the Potential for High-Quality Epitaxial CdTe Solar Cells Tao Song1 , Ana Kanevce2Te solar cell performance is limited by recombination at the grain boundaries, low carrier density (p is not strongly affected until b exceeds 0.4 eV. Index Terms -- device modeling, solar cells, epitaxial CdTe. I

  9. Spring 2012 Course Offering EEE 598 Advanced Photovoltaics

    E-print Network

    Zhang, Junshan

    for solar energy utilization. Review of solar cell physics. Wafer silicon photovoltaic technology. Survey: meng.tao@asu.edu Textbook: Solar Cell Device Physics, by S. J. Fonash (2nd edition, Academic, 2010-level course on photovoltaics such as EEE 498 Solar Energy or EEE 598 Solar Cells, or EEE 436 and consent

  10. 76 FR 68438 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-04

    ...Counties, WA, Review Period Ends: 12/05/2011, Contact: Leonard Tao 1 (866) 208- 3372. EIS No. 20110368, Draft EIS, FHWA...MT and ID, Review Period Ends: 12/05/2011, Contact: David Jacob (303) 987-6970. EIS No. 20110374, Final EIS,...

  11. 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim 4273wileyonlinelibrary.com COMMUNICATION

    E-print Network

    Rogers, John A.

    Printing of Regenerated Silk Fibroin: From Printable Forms to Printable Functions Hu Tao, Benedetto Marelli Beckman Institute for Advanced Science and Technology Urbana, IL 61801, USA M. S. Onses, Prof. J. A, antibiotics, growth factors, and antibodies during the printing process, with retention of functions

  12. Three-dimensional high order large-scale numerical investigation on the air explosion

    E-print Network

    Shu, Chi-Wang

    Three-dimensional high order large-scale numerical investigation on the air explosion Cheng Wanga , JianXu Dinga , Chi-Wang Shub, , Tao Lia a State Key Laboratory of Explosion Science and Technology the interface between the explosion products and the air. A fifth order finite difference weighted essentially

  13. Los Alamos National Laboratory | Science and people highlights from the Lujan Neutron Scattering Center at LANSCE CENTER SCIENCE & PEOPLE

    E-print Network

    hydrogen from water, scientists could design new materials to enable a hydrogen - based economy. The team at the Lujan Neutron Scattering Center to de- termine the difference in water splitting catalytic activity be of an aluminouoride of sodium and magnesium.) La3 TaO7 is an excellent catalyst for water splitting, while disordered

  14. Appl Phys B (2010) 99: 397400 DOI 10.1007/s00340-010-3992-z

    E-print Network

    Najmabadi, Farrokh

    2010-01-01

    Nonclassical hydrodynamic behavior of Sn plasma irradiated with a long duration CO2 laser pulse Y. Tao · M at Springerlink.com Abstract It was found that the electron density scale length of Sn plasma irradiated high Z plasma irradiated with a CO2 laser with wavelength of 10.6 µm has been increasingly viewed

  15. Observations of Double Layers in Earth's Plasma Sheet R. E. Ergun,1,2

    E-print Network

    Bonnell, John W.

    Observations of Double Layers in Earth's Plasma Sheet R. E. Ergun,1,2 L. Andersson,2 J. Tao,1,2 V electric fields (Ek) carried by double layers (DLs) in the plasma sheet of Earth's magnetosphere. The DL boundary layer, all during periods of strong magnetic fluctuations. These observations imply that DLs

  16. Recognition of Artificial 3D Landmarks from Depth and Color ---a first Prototype of Electronic Glasses for Blind People

    E-print Network

    Recognition of Artificial 3­D Landmarks from Depth and Color --- a first Prototype of Electronic Glasses for Blind People A. Luo a , X.­F. Zhang b , W. Tao c and H. Burkhardt b; a Mikroelektronik In this paper we present a robust method for the recog­ nition of 3D landmarks. Firstly the stereo and color

  17. Photonic Communications Laboratory by: Khanh Kieu

    E-print Network

    Kieu, Khanh

    bundles of clad fibers December 8, 1956: Curtiss makes first glass-clad fibers by rod-in- tube method May: Masoud, Jiawei, Jason Tao Liu, Vijay Nafria #12;Why fiber optics? Applications of fiber optic · Research There are also many other applications such as fiber lasers, fiber sensor #12;Why fiber optics

  18. Network Constrained Coalitional Dynamic Games and

    E-print Network

    Maryland at College Park, University of

    ;Acknowledgments · Joint work with: Pedram Hovareshti, Tao Jiang, Kiran Somasundaram, George Theodorakopoulos Examples of biological networks: [A] Yeast transcription factor-binding network; [B] Yeast protein -protein interaction network; [C] Yeast phosphorylation network ; [D] E. Coli metabolic network ; [E] Yeast genetic

  19. Mining Test Oracles of Web Search Engines Wujie Zheng1

    E-print Network

    Xie, Tao

    }@cse.cuhk.edu.hk, haoma@microsoft.com, xie@csc.ncsu.edu Abstract--Web search engines have major impact in people oracles I. INTRODUCTION Web search engines are becoming more and more impor- tant for people to searchMining Test Oracles of Web Search Engines Wujie Zheng1 , Hao Ma2 , Michael R. Lyu1 , Tao Xie3

  20. Investigating the composition of periodic nano-size column structures of anodic titanium oxide by the method of IR spectroscopy

    NASA Astrophysics Data System (ADS)

    Surganov, V. F.; Mozalev, A. M.; Lastochkina, V. A.

    1998-11-01

    Periodic column structures of anodic tantalum oxide (ATO), formed by anodizing in different regimes a Ta—Al two-layer thin-film composition in an oxalic-acid solution as well as the films of dense anodic oxide and thermal tantalum oxide, are investigated by the methods of scanning electron microscopy and reflection IR spectroscopy. It is established that the ATO nano-size columns are composed of at least three known oxide phases from a Ta—O system: TaO, TaO2 and Ta2O5. The structure of tantalum oxide compounds is amorphous with the near order (inclusions) of TaO2 rutile, rhombic Ta2O5, and ?- and ?-modifications of tantalum pentoxide. The dense-ATO films are distinguished by a more disordered structure of the oxygen compounds of tantalum and an increased content of amorphous tantalum pentoxide. The thermal-ATO films have the most ordered structure of all the oxide phases that enter in their composition and increased relative contents of ?- and ?-Ta2O3.

  1. J Intell Inf Syst DOI 10.1007/s10844-010-0141-4

    E-print Network

    Lin, Xuemin

    and Shahabi 2006; Tao et al. 2006; Yuan et al. 2005) showed that skyline analysis is very useful in multi-criteria data, how to conduct advanced analysis on uncertain data remains an open problem at large. In this paper, we tackle the problem of skyline analysis on uncertain data. We propose a novel probabilistic

  2. Applications of Geometry Processing Visual storylines: Semantic visualization of movie sequence

    E-print Network

    Lu, Aidong

    Applications of Geometry Processing Visual storylines: Semantic visualization of movie sequence Tao Chen a,n , Aidong Lu b , Shi-Min Hu a a TNList, Department of Computer Science and Technology, Tsinghua, USA a r t i c l e i n f o Article history: Received 20 August 2011 Received in revised form 13

  3. Eye-Movement Patterns Reveal Effects of Reading Skills on

    E-print Network

    Eye-Movement Patterns Reveal Effects of Reading Skills on On-line Language Processing Tao Gong #12;Motivation Most models of eye movements in reading assume that lexical properties (e.g., word, & Liversedge, 2013; Reichle et al., 2013); Our interests: Effects of reading skill differences on eye movement

  4. Incorporating Game-theoretic Rough Sets in Web-based Medical Decision Support Systems

    E-print Network

    Yao, JingTao

    in exactly express- ing an observation, effectiveness of treatment and precision of medical tests, are someIncorporating Game-theoretic Rough Sets in Web-based Medical Decision Support Systems JingTao Yao intelligent support for decision making tasks. We focus on decision making in Web-based medical decision

  5. The Role of Discursive Resources in Science Talk

    ERIC Educational Resources Information Center

    Hsu, Pei-Ling

    2013-01-01

    Tao, Oliver, and Venville's paper addresses a debate between two hypotheses of children's development of conceptual understandings of the Earth. The authors aim to investigate whether culture influences students' conceptions of the Earth. However, one questionable assumption shared among conception and conceptual change studies is that researchers…

  6. PAMM Proc. Appl. Math. Mech. 11, 783 784 (2011) / DOI 10.1002/pamm.201110380 Variational integrators for electric circuits

    E-print Network

    Ober-Blöbaum, Sina

    2011-01-01

    integrators for electric circuits Sina Ober-Blöbaum1, , Molei Tao2, , and Houman Owhadi2, 1 Computational of mechanical systems. In this work, we develop a variational integrator for the simulation of electric circuits for the simulation of the electric circuit. In this way, a variational integrator is constructed that gains several

  7. Enhancing Security of Real-Time Applications on Grids through Dynamic Scheduling

    E-print Network

    Feitelson, Dror

    Enhancing Security of Real-Time Applications on Grids through Dynamic Scheduling Tao Xie Xiao Qin* Department of Computer Science New Mexico Institute of Mining and Technology 801 Leroy Place, Socorro, New Mexico 87801-4796 {xietao, xqin}@cs.nmt.edu Abstract Real-time applications with security requirements

  8. The Moon Beyond 2002: Next Steps in Lunar Science and Exploration

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This volume contains abstracts that have been accepted for presentation at the conference on The Moon Beyond 2002: Next Steps in Lunar Science and Exploration, September 12-14, 2002, in Taos, New Mexico. Administration and publications support for this meeting were provided by the staff of the Publications and Program Services Departments at the Lunar and Planetary Institute.

  9. PatentLine: Analyzing Technology Evolution on Multi-View Patent Graphs

    E-print Network

    Li, Tao

    PatentLine: Analyzing Technology Evolution on Multi-View Patent Graphs Longhui Zhang Lei Li Tao Li patent documents provides a reasonable basis for analyzing technology evolution. In this paper, we propose a unified framework, named PatentLine, to generate a technology evolution tree for a given topic

  10. PatentDom: Analyzing Patent Relationships on Multi-View Patent Graphs

    E-print Network

    Li, Tao

    PatentDom: Analyzing Patent Relationships on Multi-View Patent Graphs Longhui Zhang Lei Li Tao Li trend. The availability of huge volumes of granted patent documents provides a reasonable basis PatentDom, to identify important patents related to key techniques from a large number of patent

  11. Patent Mining: A Survey Longhui Zhang

    E-print Network

    Li, Tao

    Patent Mining: A Survey Longhui Zhang lzhan015@cs.fiu.edu Lei Li lli003@cs.fiu.edu Tao Li taoli Patent documents are important intellectual resources of protecting interests of individuals, organizations and com- panies. Different from general web documents, patent doc- uments have a well

  12. Degraded Text Recognition Using Word Collocation and Visual Inter-Word Constraints

    E-print Network

    Degraded Text Recognition Using Word Collocation and Visual Inter-Word Constraints Tao Hong©cs.buffalo, edu Abstract Given a noisy text page, a word recognizer can generate a set of candidates for each word image. A relaxation algorithm was proposed previously by the authors that uses word collocation

  13. Prying Apart Ruddlesden-Popper Phases: Exfoliation into Sheets and Nanotubes for Assembly of Perovskite

    E-print Network

    of Perovskite Thin Films Raymond E. Schaak and Thomas E. Mallouk* Department of Chemistry, The Pennsylvania)] surface, forming perovskite monolayers. Above pH 9.5, TBAxH2-xSrLaTi2TaO10 sheets tile to densely cover and titanoniobates generally do not adhere to polycationic surfaces. Introduction Perovskite-type transition

  14. IEEE PHOTONICS TECHNOLOGY LETTERS, VOL. 22, NO. 3, FEBRUARY 1, 2010 149 Statistical Analysis of Optical Signal-to-Noise Ratio

    E-print Network

    Wai, Ping-kong Alexander

    of emerging dynamic fiber optic communication networks [1]. In particular, monitoring optical signalIEEE PHOTONICS TECHNOLOGY LETTERS, VOL. 22, NO. 3, FEBRUARY 1, 2010 149 Statistical Analysis of Optical Signal-to-Noise Ratio Monitoring Using Delay-Tap Sampling F. N. Khan, Alan Pak Tao Lau, Zhaohui Li

  15. ERROR ESTIMATES FOR APPROXIMATE SOLUTIONS FOR NONLINEAR SCALAR CONSERVATION LAWS

    E-print Network

    ERROR ESTIMATES FOR APPROXIMATE SOLUTIONS FOR NONLINEAR SCALAR CONSERVATION LAWS TAO TANG z laws. We review the recent work on error estimates for nonlinear scalar conservation laws estimates for approx­ imate solutions to scalar conservation laws. The methods of analysis include matching

  16. The Fault Attack ECDLP Revisited Mingqiang Wang1

    E-print Network

    International Association for Cryptologic Research (IACR)

    The Fault Attack ECDLP Revisited Mingqiang Wang1 Xiaoyun Wang1,2 , and Tao Zhan3 1. School: wangmingqiang@sdu.edu.cn Abstract Biehl et al.[2] proposed a fault-based attack on elliptic curve cryptog- raphy. In this paper, we refined the fault attack method. An elliptic curve E is defined over prime field Fp with base

  17. Loss of Heterozygosity of the Rb Gene Correlates with pRb Protein Expression and Associates with p53 Alteration in Human

    E-print Network

    Xing, Eric P.

    of cancer involving bladder, lung, breast, head and neck, and other organs (9­25). However, it is not always53 Alteration in Human Esophageal Cancer1 Eric Poe Xing,2 Guang-Yu Yang,2 Li-Dong Wang, Stephanie Tao Shi, and Chung S. Yang3 Laboratory for Cancer Research, College of Pharmacy, Rutgers University

  18. Eye Contact Reminder System for People with Autism

    E-print Network

    Gnawali, Omprakash

    Eye Contact Reminder System for People with Autism Xi Wang1, Nicholas Desalvo1, Xi Zhao1, Tao Feng1 of Houston1 The Autism Research Laboratory, The University of Texas Health Science Center2 Email: {xiwang--Avoiding eye contact behavior has been character- istic of individuals with autism. Such behavior prevents

  19. 75 FR 2889 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-International...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-19

    ... published a notice in the Federal Register pursuant to Section 6(b) of the Act on June 28, 1996 (61 FR 33774... Federal Register pursuant to Section 6(b) of the Act on December 12, 2008 (73 FR 75772). Patricia A. Brink... REPUBLIC OF CHINA; Lenovo, Quarry Bay, HONG KONG- CHINA; and Quanta Computer Inc., Tao Yuan Shien,...

  20. 78 FR 42976 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-International...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-18

    ... 28, 1996 (61 FR 33774). The last notification was filed with the Department on December 15, 2009. A... FR 2889). Patricia A. Brink, Director of Civil Enforcement, Antitrust Division. BILLING CODE 4410-11.... Also, Foxconn, Taipei Hsien, TAIWAN; and Quanta Computer, Tao Yuan Shine, TAIWAN, have withdrawn...

  1. HIGH-ORDER WENO SCHEMES FOR HAMILTONJACOBI EQUATIONS ON TRIANGULAR MESHES

    E-print Network

    Zhang, Yong-Tao

    volume schemes and finite element schemes, which are very useful for conservation laws. The problem few. We have the very good first- and second-order finite volume­type schemes of Abgrall [2] and ENOHIGH-ORDER WENO SCHEMES FOR HAMILTON­JACOBI EQUATIONS ON TRIANGULAR MESHES YONG-TAO ZHANG AND CHI

  2. CONSTELLATIONS IN Pd BRIAN COOK AKOS MAGYAR

    E-print Network

    Magyar, Akos

    CONSTELLATIONS IN Pd BRIAN COOK ´AKOS MAGYAR Abstract. Let A be a subset of positive relative upper such a result was obtained by Tao [9], showing that the Gaussian primes contain arbitrary constellations. In the same paper the problem of finding constellations in dense subsets of Pd was raised and briefly

  3. Resolution of high order WENO schemes for complicated flow structures

    E-print Network

    Zhang, Yong-Tao

    Resolution of high order WENO schemes for complicated flow structures Jing Shi a , Yong-Tao Zhang b essentially non- oscillatory (WENO) schemes for computing solutions containing both discontinuities discontinuities and complex solution features, it is more economical in CPU time to use higher order WENO schemes

  4. 76 FR 17444 - Notice of Inventory Completion: Colorado Historical Society (History Colorado), Denver, CO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-29

    ... National Park Service Notice of Inventory Completion: Colorado Historical Society (History Colorado... (History Colorado), Denver, CO. The human remains were removed from Howiri Ruin (LA 71), Taos County, NM... remains was made by the Colorado Historical Society (History Colorado) professional staff in...

  5. Accurate Analytic Potential and Born-Oppenheimer Breakdown Functions for MgH and MgD from a Direct-Potential-Fit Data Analysis

    E-print Network

    Le Roy, Robert J.

    Accurate Analytic Potential and Born-Oppenheimer Breakdown Functions for MgH and MgD from a Direct-Potential-Fit Data Analysis Robert D. E. Henderson,*,, Alireza Shayesteh,,§ Jason Tao, Carl C. Haugen, Peter F. Bernath,, and Robert J. Le Roy*, Department of Chemistry, University of Waterloo, Waterloo, Ontario N2L 3

  6. An Efficient and Flexible Host-FPGA PCIe Communication Library

    E-print Network

    Cong, Jason "Jingsheng"

    PCIe hard IP core) at the FPGA side. They also have to create special software code (e.g., driversAn Efficient and Flexible Host-FPGA PCIe Communication Library Jian Gong,1 Tao Wang,1,3 Jiahua Chen-performance interconnection between a host processor and FPGA accelerators is in much demand. Among various interconnection

  7. Fast sweeping methods for eikonal equations on triangular meshes

    E-print Network

    Zhao, Hongkai

    Fast sweeping methods for eikonal equations on triangular meshes Jianliang Qian1 , Yong-Tao Zhang2 , and Hong-Kai Zhao3 Abstract The original fast sweeping method, which is an efficient iterative method propose novel ordering strategies so that the fast sweeping method can be extended efficiently and easily

  8. Mouse Repository Strain Details

    Cancer.gov

    Qingcong Lin, Alan B. Clark, Scott D. McCulloch, Tao Yuan, Roderick T. Bronson, Thomas A. Kunkel, and Raju Kucherlapati. Increased Susceptibility to UV-Induced Skin Carcinogenesis in Polymerase eta-deficient Mice. Cancer Res. 66, 87-94, 2006.

  9. This article was downloaded by:[University of Michigan] On: 25 February 2008

    E-print Network

    Rosenberg, Noah

    This article was downloaded by:[University of Michigan] On: 25 February 2008 Access Details February 2008 To cite this Article: Rosenberg, Noah A. and Tao, Randa (2008) 'Discordance of Species Trees to this article: DOI: 10.1080/10635150801905535 URL: http://dx.doi.org/10.1080/10635150801905535 PLEASE SCROLL

  10. VISCOSITY METHODS FOR PIECEWISE SMOOTH SOLUTIONS TO SCALAR CONSERVATION LAWS

    E-print Network

    VISCOSITY METHODS FOR PIECEWISE SMOOTH SOLUTIONS TO SCALAR CONSERVATION LAWS TAO TANG AND ZHEN­ tions of all these patterns), then the error of viscosity solution to the inviscid solution is bounded.1) subject to the initial condition u(x; 0) = u 0 (x); \\Gamma1 ! x ! 1: (0.2) The viscosity method

  11. 3 CFR 8946 - Proclamation 8946 of March 25, 2013. Establishment of the Río Grande del Norte National Monument

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Yuta, jut up from this surrounding plateau. Canyons, volcanic cones, wild rivers, and native grasslands... the Río Grande Wild and Scenic River by a broad swath of sagebrush and grassland, the Río San Antonio... Taos Plateau's sagebrush shrub habitat and native grasslands, which stretch for thousands of acres...

  12. Excitation of electron cyclotron harmonic waves in the inner Saturn magnetosphere within local plasma injections

    E-print Network

    Gurnett, Donald A.

    Excitation of electron cyclotron harmonic waves in the inner Saturn magnetosphere within local magnetosphere. Using measured electron distributions from the Cassini plasma spectrometer, we calculated local and their roles in electron dynamics in the Saturnian magnetosphere. Citation: Tao, X., R. M. Thorne, R. B. Horne

  13. This article was published in the above mentioned Springer issue. The material, including all portions thereof, is protected by copyright;

    E-print Network

    Kaber, David B.

    robot feature design effects on user perceptions and emotional responses Tao Zhang · David B. Kaber robot interface features on elderly perceptions and emotional responses in a simulated medicine delivery, there are commercially available robots (e.g., Aethon Tug) that can navigate autonomously in large-scale hospital

  14. An Inventory of Natural, Human, and Social Overhead Capital Resources in North-Central New Mexico.

    ERIC Educational Resources Information Center

    Carruthers, Garrey; Eastman, Clyde

    Concerned with the north-central area of New Mexico (Rio Arriba, Taos, Colfax, Mora, Santa Fe, and San Miguel counties), this inventory describes the situation and delineation of the region, the natural resources (physical characteristics, land, land-ownership patterns, land-use patterns, land-title problems, water resources, and minerals); human…

  15. Verification of Gyrokinetic Particle Simulation of Current-driven Instability in Fusion Plasmas. III. Collisionless Tearing Mode

    E-print Network

    Lin, Zhihong

    verified in the fluid limit. Simulations verify that the linear growth rate of the single tearing mode. III. Collisionless Tearing Mode Dongjian Liu 1, 2 , Jian Bao 3 , Tao Han 1 , Jiaqi Wang 1 , Zhihong of California, Irvine CA 92697, USA. E-mail: zhihongl@uci.edu Abstract A finite-mass electron fluid model

  16. Supplement of Atmos. Chem. Phys., 15, 85978614, 2015 http://www.atmos-chem-phys.net/15/8597/2015/

    E-print Network

    Meskhidze, Nicholas

    of Effects of urban land expansion on the regional meteorology and air quality of eastern China W. Tao et al. Given a certain large-scale synoptic background, the magnitude of urban land climatic perturbation did from the CC-BY 3.0 licence. #12;S1 Urban land expansion scenarios Figure S1: The original main land use

  17. Global Structure and Asymptotic Behavior of Weak Solutions to Flood Wave Equations

    E-print Network

    Global Structure and Asymptotic Behavior of Weak Solutions to Flood Wave Equations Tao Luo: Flood wave equations, Weak solutions, Relaxation, Shock waves Abstract The present paper concerns with the global structure and asymptotic behavior of the discontinuous solutions to flood wave equations

  18. Self-Rectifying Effect in Resistive Switching Memory Using Amorphous InGaZnO

    NASA Astrophysics Data System (ADS)

    Lee, Jin-Woo; Kwon, Hyeon-Min; Kim, Myeong-Ho; Lee, Seung-Ryul; Kim, Young-Bae; Choi, Duck-Kyun

    2014-05-01

    Resistance random access memory (ReRAM) has received attention as next-generation memory because of its excellent operating properties and high density integration capability as a crossbar array. However, the application of the existing ReRAM as a crossbar array may lead to crosstalk between adjacent cells due to its symmetric I- V characteristics. In this study, the self-rectifying effect of contact between amorphous In-Ga-Zn-O (a-IGZO) and TaO x was examined in a Pt/a-IGZO/TaO x /Al2O3/W structure. The experimental results show not only self-rectifying behavior but also forming-free characteristics. During the deposition of a-IGZO on the TaO x , an oxygen-rich TaO x interfacial layer was formed. The rectifying effect was observed regardless of the interface formation and is believed to be associated with Schottky contact formation between a-IGZO and TaO x . The current level remained unchanged despite repeated DC sweep cycles. The low resistance state/high resistance state ratio was about 101 at a read voltage of -0.5 V, and the rectifying ratio was about 103 at ±2 V.

  19. Natural Event Summarization School of Computer Science

    E-print Network

    Li, Tao

    Natural Event Summarization Yexi Jiang School of Computer Science Florida International University summarization, namely how to concisely summarize temporal events [14, 15, 25]. Current state-of-art event, 10532, USA perng@us.ibm.com Tao Li School of Computer Science Florida International University Miami, FL

  20. A short geometric proof of a conjecture of Fulton N. Ressayre

    E-print Network

    Ressayre, Nicolas

    geometric proof of a Fulton conjecture about the Littlewood-Richardson coefficients. This conjecture), (C)) R3n : A, B, C H(n) s.t. A + B + C = 0}. In 1962, Horn conjectured in [Hor62] an inductive-Tao theorem ([KT99]) implies this conjecture (see Section 2 for details). 1.2 Littlewood-Richardson

  1. LittlewoodRichardson polynomials A. I. Molev

    E-print Network

    Sydney, University of

    Littlewood­Richardson polynomials A. I. Molev School of Mathematics and Statistics University in the parameters which we call the Littlewood­Richardson polynomials. We give a combinatorial rule. Knutson and T. Tao by using combinatorics of puzzles, and the stability property can also be derived from

  2. 7 Yang, Z. et al. (2005) Arabidopsis ERF4 is a transcriptional repressor capable of modulating ethylene and abscisic acid responses. Plant Mol.

    E-print Network

    2005-01-01

    ethylene and abscisic acid responses. Plant Mol. Biol. 58, 585­596 8 Song, C-P. et al. (2005) Role of an Arabidopsis AP2/EREBP-type transcriptional repressor in abscisic acid and drought stress responses. Plant Cell and light signaling networks? Trends Plant Sci. 11, 4­7 10 Tao, L. et al. (2005) RAC GTPases in tobacco

  3. The Plumed Serpent and the Red Atlantis.

    ERIC Educational Resources Information Center

    Willard, William

    1988-01-01

    Examines work of author D.H. Lawrence and John Collier, later Bureau of Indian Affairs Commissioner, during 1920s when they stayed as Mabel Dodge Luhan's guests in Taos, New Mexico. Examines their perceptions of Pueblo Indian culture, federal-Indian relationship, and Indian influences on Lawrence's and Collier's work. (TES)

  4. engineering home news home press releases subscribe to e-news annual re UT Arlington Moving Ideas from Laboratories to Marketplace

    E-print Network

    Chiao, Jung-Chih

    sear engineering home news home press releases subscribe to e-news annual re UT Arlington Moving-effective Surface Texture on Solar Cells Electrical Engineering Associate Professor Meng Tao and Assistant Professor Weidong Zhou have developed a unique process that should reduce the cost of solar-generated electricity

  5. Long Range Audio and Audio-Visual Event Detection Using a Laser Doppler Vibrometer

    E-print Network

    Zhu, Zhigang

    , is a long-range, non-contact acoustic measurement device to detect the speed of the target's vibration basedLong Range Audio and Audio-Visual Event Detection Using a Laser Doppler Vibrometer Tao Wangab from a large distance. Setting up a long range microphone array and performing geo-calibration of both

  6. Controlled Strain on a Double-Templated Textured Polymer Film: a New Approach to Patterned Surfaces with Bravais Lattices and Chains

    E-print Network

    Wu, Shin-Tson

    * Corresponding author. E-mail: zlwang@nju.edu.cn. (1) Xia, Y.; Rogers, J. A.; Paul, K. E.; Whitesides, G. M. Chem. ReV. 1999, 99, 1823. (2) Geissler, M.; Xia, Y. AdV. Mater. 2004, 16, 1249. (3) Wouters, D.; Schubert with Bravais Lattices and Chains Mingwei Zhu, Yumei Li, Tao Meng, Peng Zhan, Jie Sun, Jun Wu, Zhenlin Wang

  7. 76 FR 70120 - Environmental Management Site-Specific Advisory Board, Northern New Mexico

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-10

    ... Environmental Management Site-Specific Advisory Board, Northern New Mexico AGENCY: Department of Energy. ACTION...-Specific Advisory Board (EM SSAB), Northern New Mexico. The Federal Advisory Committee Act (Pub. L. 92-463... Taos Highway 68, San Juan Pueblo, New Mexico 87566. FOR FURTHER INFORMATION CONTACT: Menice...

  8. Structurally Defined Nanoscale Sheets from Self-Assembly of Collagen-Mimetic Peptides

    E-print Network

    Salaita, Khalid

    Structurally Defined Nanoscale Sheets from Self-Assembly of Collagen-Mimetic Peptides Tao Jiang of two collagen-mimetic peptide sequences, NSI and NSII, that self-assemble into structurally defined packing of collagen triple helices in two dimensions. These nanosheet assemblies represent a novel

  9. Probe Selection Algorithms with Applications in the Analysis of

    E-print Network

    Della Vedova, Gianluca

    Borneman1 Marek Chrobak2 Gianluca Della Vedova3 Andres Figueroa2 Tao Jiang2 1 Dept. Plant Pathology, Univ in the Analysis of Microbial Communiti #12;In Vitro Experiment Microbial communities Clones Probe Selection communities Probes Clones Probe Selection Algorithms with Applications in the Analysis of Microbial Communiti

  10. Constraining groundwater flow in the glacial drift and saginaw aquifers in the Michigan Basin through helium

    E-print Network

    through helium concentrations and isotopic ratios T. WEN1 , M. C. CASTRO1 , C. M. HALL1 , D. L. PINTI2, tritium Received 28 May 2014; accepted 19 February 2015 Corresponding author: Tao Wen, Department of Earth (2015) INTRODUCTION High salinity fluids are found at all depths in the Michigan Basin, from the deep

  11. Adaptive Load Sharing for Clustered Digital Library Servers

    E-print Network

    Yang, Tao

    Adaptive Load Sharing for Clustered Digital Library Servers Huican Zhu Tao Yang Qi Zheng David digital library (ADL) servers. The ADL system, which provides on­line information searching and browsing with the advent of Internet tech­ nology. Digital library (DL) systems [14], which provide on­line retrieval

  12. Adaptive Load Sharing for Clustered Digital Library Servers

    E-print Network

    Yang, Tao

    Adaptive Load Sharing for Clustered Digital Library Servers Huican Zhu Tao Yang Qi Zheng David investigates load balancing strategies for clustered Alexandria digital library (ADL) servers. The ADL system technology. Digi­ tal library (DL) systems[8], which provide on­line retrieval and processing of digitized

  13. Blind Optical Aberration Correction by Exploring Geometric and Visual Priors

    E-print Network

    Wang, Jue

    Blind Optical Aberration Correction by Exploring Geometric and Visual Priors Tao Yue1 Jinli Suo1 School of Electronic Science and Engineering, Nanjing University Abstract Optical aberration widely exists in optical imaging sys- tems, especially in consumer-level cameras. In contrast to previous

  14. 184 IEEE TRANSACTIONS ON MULTIMEDIA, VOL. 12, NO. 3, APRIL 2010 Video Annotation Through Search

    E-print Network

    California at Santa Barbara, University of

    by the words in the collective annota- tion vocabulary of all the database documents. A graph reinforce- ment and Graph Reinforcement Mining Emily Moxley, Tao Mei, Member, IEEE, and B. S. Manjunath, Fellow, IEEE of modern information and online media databases with in- dependent annotation instances, we present

  15. Collaborative Filtering with the Trace Norm: Learning, Bounding, and Transducing

    E-print Network

    Linial, Nathan "Nati"

    , there are no distribution-free, non-trivial learning guaran- tees currently known. In this paper, we bridge this gap), Salakhutdinov and Mnih (2007), Bach (2008), Cand`es and Tao (2009)). However, in terms of distribution-free. In collaborative filtering, this is an extremely unrealistic assumption. For example, in the Netflix challenge

  16. Cooperative Jamming for Secrecy in Decentralized Wireless Networks

    E-print Network

    Zhou, Xiangyun "Sean"

    Cooperative Jamming for Secrecy in Decentralized Wireless Networks Xiangyun Zhou, Meixia Tao.zhou@anu.edu.au, mxtao@sjtu.edu.cn, rodney.kennedy@anu.edu.au Abstract--Cooperative jamming as a physical layer security systems with a small number of nodes, we investigate the use of cooperative jamming for providing secrecy

  17. Department of Biochemistry Supervisor: Dr. Andrew MacMillan

    E-print Network

    MacMillan, Andrew

    Dr. Tao Wu Department of Biochemistry Supervisor: Dr. Andrew MacMillan Originally from Penglai. At PKU I gained research experience in tissue culture and virus vaccine studies. I was then admitted to the Department of Biochemistry at University of Alberta to pursue my graduate studies. After finishing my

  18. WORKING QUANTUM EFFICIENCY OF CDTE SOLAR CELL Zimeng Cheng

    E-print Network

    WORKING QUANTUM EFFICIENCY OF CDTE SOLAR CELL Zimeng Cheng 1 , Kwok Lo 2 , Jingong Pan 1 , Dongguo Chen 1 , Tao Zhou 2 , Qi Wang 3 , George E. Georgiou 1 , Ken K. Chin 1 1 Apollo CdTe Solar Energy Renewable Energy Laboratory (NREL), Golden, CO 80401 USA ABSTRACT For p-CdTe/n-CdS solar cell

  19. We Shared the Same Chapter: Collaboration, Learning, and Transformation from the 2008 Subsistence, the Environment, and Community Well-Being Native Youth Exchange in Old Harbor, Alaska Project

    ERIC Educational Resources Information Center

    Richmond, Laurie; Di Piero, Daniela; Espinoza, Flowers; Simeonoff, Teacon; Faraday, Margaret

    2010-01-01

    On a small island belonging to the Alutiiq people of Old Harbor, 11 people sat around a campfire. Two community leaders, a nonprofit organizer, an academic scholar, a native filmmaker, and six young people from the Indian reservation of Taos Pueblo in New Mexico gathered after a day of interacting with Old Harbor residents--fishing, hunting and…

  20. Automated Detection of API Refactorings in Libraries Kunal Taneja1

    E-print Network

    Xie, Tao

    Automated Detection of API Refactorings in Libraries Kunal Taneja1 Danny Dig2 Tao Xie1 1 Department from scratch but reuse software libraries. In theory, the APIs of a library should be stable, but in practice they do change and thus require changes in software that reuses the library. Our previous study

  1. Using DNA Microarray to Identify Sp1 as a Transcriptional Regulatory Element of Insulin-like Growth Factor-1 in Cardiac Muscle Cells

    E-print Network

    Kibler, Dennis F.

    -like Growth Factor-1 in Cardiac Muscle Cells Tao Li1 , Yung-Hsiang Chen1,2 , Tsun-Jui Liu1,2 , Jia Jia1 during cardiac muscle growth, repair, and remodeling in normal and abnormal cardiac muscle. #12 important cardiac muscle functions (1,2). In theory, a growth factor such as IGF-1 activates a specific set

  2. Modelling Office Energy Consumption: An Agent Based Approach , Peer-Olaf Siebers1

    E-print Network

    Aickelin, Uwe

    1 Modelling Office Energy Consumption: An Agent Based Approach Tao Zhang1 , Peer-Olaf Siebers1 integrates four important elements, i.e. organisational energy management policies/regulations, energy, to simulate the energy consumption in office buildings. With the model, we test the effectiveness of different

  3. Watch It

    ERIC Educational Resources Information Center

    Bolch, Matt

    2008-01-01

    For the school chief information officer (CIO), safeguarding students and facilities is as much a part of the job description as keeping the data networks running and the servers protected from hackers. This article describes how two districts, Miami-Dade County Public Schools and Taos Municipal Schools, secured their surveillance systems. The…

  4. Assignment of Orthologous Genes via Genome Rearrangement

    E-print Network

    Lonardi, Stefano

    Assignment of Orthologous Genes via Genome Rearrangement Xin Chen, Jie Zheng, Zheng Fu, Peng Nan, Yang Zhong, Stefano Lonardi, and Tao Jiang Abstract--The assignment of orthologous genes between a pair sequence similarity does not clearly delineate the evolutionary relationship among genes of the same

  5. El Nino -Southern Oscillations: Phenomenology and dynamical background Eli Tziperman

    E-print Network

    Tziperman, Eli

    Lecture 1 El Nino - Southern Oscillations: Phenomenology and dynamical background Eli Tziperman 1 and animations are available on the El Nino theme page at http://www.pmel.noaa.gov/tao/elnino/nino- home anomalies during La Nina, normal conditions and during El Nino are shown in Fig. 15. The slope

  6. A Peptide Motif Consisting of Glycine, Alanine, and Valine Is Required for the Fibrillization and Cytotoxicity of Human R-Synuclein

    E-print Network

    Tian, Weidong

    and Cytotoxicity of Human R-Synuclein Hai-Ning Du, Lin Tang,§ Xiao-Ying Luo, Hong-Tao Li, Jun Hu,§,| Jia-Wei Zhou, in the fibrillization and cytotoxicity of human R-Syn. Mutagenesis combined with thioflavin T fluorescence detection, atomic force microscopic imaging, and cytotoxicity assays reveal that deletion of this sequence

  7. A Study on the Application of Laozi's Thoughts on Educational Leadership and Management

    ERIC Educational Resources Information Center

    Wen, Lian-shiung; Hwang, Kevin P.

    2008-01-01

    This paper attempts to apply historical methods to help understand the relationship between the philosophy espoused in the works of Laozi or Tao De Ching and educational leadership. The objective is to study the thought of Laozi regarding leadership, to identify ideas and solutions that can be applied in modern educational management, as well as…

  8. Nanotechnology It's not just a miniature

    E-print Network

    Maryland at College Park, University of

    Graphene on SiO2 Surface/statistical issues: Interfacial contacts Transport in low-D nanowires thin sheets decorating a step -- C. Tao et al, PRB, 73, 125436 (2006) 40nm #12;C60 and Step Motion · Silver atomic motion

  9. Active Balancing Using Gyroscopes for a Small Humanoid Robot

    E-print Network

    Baltes, Jacky

    Active Balancing Using Gyroscopes for a Small Humanoid Robot Jacky Baltes and Sara McGrath and John-PIE-PIE, a small humanoid robot given rate feedback from two RC gyroscopes. TAO-PIE-PIE is a fully autonomous small and 2003. The feedback control law is based solely on the rate information from two RC gyroscopes

  10. THE TAIWAN-AMERICAN OCCULTATION SURVEY PROJECT STELLAR VARIABILITY. I. DETECTION OF LOW-AMPLITUDE {delta} SCUTI STARS

    SciTech Connect

    Kim, D.-W.; Protopapas, P.; Alcock, C.; Wright, N. J.; Bianco, F. B.; Lehner, M. J.; Byun, Y.-I.; Kyeong, J.; Lee, B.-C.; Axelrod, T.; Chen, W.-P.; Lin, H.-C.; Coehlo, N. K.; Rice, J. A.; Cook, K. H.; Marshall, S. L.; Dave, R.; King, S.-K.; Lee, T.; Porrata, R.

    2010-02-15

    We analyzed data accumulated during 2005 and 2006 by the Taiwan-American Occultation Survey (TAOS) in order to detect short-period variable stars (periods of {approx}<1 hr) such as {delta} Scuti. TAOS is designed for the detection of stellar occultation by small-size Kuiper Belt Objects and is operating four 50 cm telescopes at an effective cadence of 5 Hz. The four telescopes simultaneously monitor the same patch of the sky in order to reduce false positives. To detect short-period variables, we used the fast Fourier transform algorithm (FFT) in as much as the data points in TAOS light curves are evenly spaced. Using FFT, we found 41 short-period variables with amplitudes smaller than a few hundredths of a magnitude and periods of about an hour, which suggest that they are low-amplitude {delta} Scuti stars. The light curves of TAOS {delta} Scuti stars are accessible online at the Time Series Center Web site (http://timemachine.iic.harvard.edu)

  11. MAPO: Mining and Recommending API Usage Patterns Hao Zhong1,2

    E-print Network

    Xie, Tao

    MAPO: Mining and Recommending API Usage Patterns Hao Zhong1,2 , Tao Xie3, , Lu Zhang1,2 , Jian Pei4 by invoking methods provided in their APIs. Those API methods, however, are often complex and not well documented. To get familiar with how those API methods are used, programmers often exploit a source code

  12. An Empirical Study on Evolution of API Documentation , Hao Zhong1

    E-print Network

    Xie, Tao

    An Empirical Study on Evolution of API Documentation Lin Shi1 , Hao Zhong1 , Tao Xie3 , and Mingshu,zhonghao}@itechs.iscas.ac.cn, xie@csc.ncsu.edu, mingshu@iscas.ac.cn Abstract. With the evolution of an API library, its documentation also evolves. The evolution of API documentation is common knowledge for programmers and library

  13. Static Detection of API Error-Handling Bugs via Mining Source Code

    E-print Network

    Young, R. Michael

    Static Detection of API Error-Handling Bugs via Mining Source Code Mithun Acharya and Tao Xie}@csc.ncsu.edu Abstract Incorrect handling of errors incurred after API invoca- tions (in short, API errors) can lead to security and robust- ness problems, two primary threats to software reliability. Correct handling of API

  14. Mining API Error-Handling Specifications from Source Code

    E-print Network

    Xie, Tao

    Mining API Error-Handling Specifications from Source Code Mithun Acharya and Tao Xie Department}@csc.ncsu.edu Abstract. API error-handling specifications are often not documented, necessi- tating automated present a novel framework for mining API error- handling specifications automatically from API client code

  15. Grover

    USGS Multimedia Gallery

    Grover was built in just four months in 1971 by the USGS Astrogeology Research Program (called the Branch of Astrogeology at the time) and used to training Apollo 15-17 astronauts at the Cinder Lakes training ground near Flagstaff, in California's Mojave Desert, and in the Rio Grande gorge near Taos...

  16. The electrochemical synthesis of TiC reinforced Fe based composite powder from titanium-rich slag

    E-print Network

    Sun, Lin; Song, Qiushi; Xu, Qian; Ning, Zhiqiang; Lu, Xionggang; Fray, Derek

    2015-03-18

    , B35, 223-233. [20] A. M. Abdelkader , D. J. Fray, J. Eur. Ceram . Soc., 2012, 32, 4481-4487. [21] Q. S. Song, Q. Xu, R. Tao, X. Kang. Int. J. Electrochem. Sci., 2012, 7, 272- 281. [22] L.M. Berger, W. Gruner, E. Landgholf, S. Stolle, Int. J...

  17. CONSTRAINED TOTAL VARIATIONAL DEBLURRING MODELS AND FAST ALGORITHMS BASED ON ALTERNATING DIRECTION METHOD OF MULTIPLIERS

    E-print Network

    Chan, Raymond

    METHOD OF MULTIPLIERS RAYMOND H. CHAN1 , MIN TAO2 , AND XIAOMING YUAN3 Abstract. The total variation (TV from TV-based methods do not usually stay in a given dynamic range, and hence projection is required of the given TV model. In this paper, we show that one can get much more accurate solutions by imposing box

  18. Different Perspectives of Cultural Mediation: Implications for the Research Design on Studies Examining Its Effect on Students' Cognition

    ERIC Educational Resources Information Center

    Teo, Tang Wee

    2013-01-01

    In this forum, I extend Tao, Oliver, and Venville's paper "Chinese and Australian children's understanding of the earth: a cross cultural study of conceptual development" to discuss the different views on culture and cultural mediation. I tease out nuances in the viewpoints to suggest three ways to theoretically frame studies examining cultural…

  19. 7. Penn, A. A., Riquelme, P. A., Feller, M. B. & Shatz, C. J. Competition in retinogeniculate patterning driven by spontaneous activity. Science 279, 21082112 (1998).

    E-print Network

    Ruthazer, Edward

    1998-01-01

    of postsynaptic APs and EPSPs. Science 275, 213­215 (1997). 18. Zhang, L. I., Tao, H. W., Holt, C. E., Harris, W. Mehta, M. R., Barnes, C. A. & McNaughton, B. L. Experience-dependent, asymmetric expansion of hippocampal place fields. Proc. Natl Acad. Sci. USA 94, 8918­8921 (1997). 26. Mehta, M. R., Quirk, M. C

  20. Supporting Information: Information processing and signal integration in bacterial quorum sensing

    E-print Network

    Mehta, Pankaj

    Pankaj Mehta, Sidhartha Goyal, Tao Long, Bonnie Bassler, Ned S. Wingreen Dept. of Molecular Biology on experimental evidence, that the receptors have state-independent phosphatase activities, which we denote pX and pY . The phosphorelay can be modeled using simple differential equations of the form d[LuxU-P] dt

  1. A Survey on Wavelet Applications in Data Mining Department of

    E-print Network

    Li, Tao

    A Survey on Wavelet Applications in Data Mining Tao Li Department of Computer Science Univ in the use of wavelet methods in various data mining processes. However, there has been written presents a high-level data-mining framework that reduces the overall process into smaller components

  2. Ahmad Salim, Salam Zummo, and Samir Al-Presented by

    E-print Network

    Al-Ghadhban, Samir

    Antenna Systems Literature Survey LSSTC System Model Scheduling criteria Conclusions #12; MIMO increases with one Tx and two Rx antennas. In [Tao et al, 2001] a combination of BLAST and STC was implemented which scheduling criteria to schedule users with LSSTC receivers. Some numerical results will be presented

  3. Supplementary Fig. 1. Geographical definition of the fourteen regions. NPO North Pacific Ocean, NAM North America, NAO North Atlantic Ocean, EUR Europe, ASI Asia, TPO

    E-print Network

    Meskhidze, Nicholas

    Ocean, TAO ­ Tropical Atlantic Ocean, AFR ­ Africa, TIO ­ Tropical Indian Ocean, SPO ­ South Pacific Ocean, SAM ­ South America, SAO ­ South Atlantic Ocean, SIO ­ South Indian Ocean, OCE ­ Oceania. 5 #12Supplementary Fig. 1. Geographical definition of the fourteen regions. NPO ­ North Pacific Ocean

  4. A Flow-Based Approach to Vehicle Detection and Background Mosaicking in Airborne Video

    E-print Network

    Yalcin, Hulya

    . Silver, J. Krant, M. Antone, and T. Strat. Multiple- hypothesis tracking of multiple ground targets from. PAMI, 23(8):873­889, August 2001. [7] H. Tao, H. Sawhney, and R. Kumar. Object tracking with bayesian. We propose a Bayesian framework for estimating dense optical flow over time that explicitly estimates

  5. Analysis of Average Signal-to-Interference-Noise Ratio for Indoor UWB Rake Receiving System

    E-print Network

    Kim, Dong In

    Analysis of Average Signal-to-Interference-Noise Ratio for Indoor UWB Rake Receiving System Tao Jia the multiple- access performance of a time-hopping (TH) pulse position modulation (PPM) UWB system based on this framework, we can compare the performance of UWB Rake receiving system in different types of indoor wireless

  6. MODA: Automated Test Generation for Database Applications via Mock Objects

    E-print Network

    Xie, Tao

    MODA: Automated Test Generation for Database Applications via Mock Objects Kunal Taneja1 , Yi Zhang2 , Tao Xie1 1Department of Computer Science, North Carolina State University, Raleigh, NC, 27695 used in assuring the quality of database applications. It is often prohibitively expensive to man

  7. OCSOY ET AL. VOL. 7 ' NO. 1 ' 417427 ' 2013 www.acsnano.org

    E-print Network

    Tan, Weihong

    drug delivery, and magnetic resonance ima- ging (MRI).7,8 Recently, multifunctional hybrid nano, therapy, drug delivery, proteomics, and bio- sensing and surface plasmon resonance (SPR) purposes.4À6 Ibrahim Shukoor, Xiangling Xiong,, Tao Chen, David H. Powell, and Weihong Tan,,* CenterforResearchattheBio/Nano

  8. Cloud Detection over Snow and Ice Using MISR Data , Eugene E. Clothiaux

    E-print Network

    Yu, Bin

    Cloud Detection over Snow and Ice Using MISR Data Tao Shi , Bin Yu , Eugene E. Clothiaux , and Amy J. Braverman Abstract Clouds play a major role in Earth's climate and cloud detection prediction and global climate model studies. To advance the observational capabilities of detecting clouds

  9. PedPhase: Haplotype Inference for Pedigree Data Summary: We have developed a computer program consisting of four algorithms for inferring haplotypes from (unphased)

    E-print Network

    Li, Jing

    between genetic variations and phenotypic variations (such as disease status, quantitative traits, etc programs for inferring haplotype information from genotype data are highly demanded. A recent comprehensivePedPhase: Haplotype Inference for Pedigree Data Jing Li Tao Jiang Abstract Summary: We have

  10. A Decentralized Sleep Mechanism in Heterogeneous Cellular Networks with QoS Constraints

    E-print Network

    Tao, Meixia "Melissa"

    1 A Decentralized Sleep Mechanism in Heterogeneous Cellular Networks with QoS Constraints Ping Ren and Meixia Tao, Senior Member, IEEE Abstract--We introduce a sleep mechanism for energy effi- ciency band. The strategy is to put high-power macro base stations into sleep mode and offload the users

  11. Expression, Purification, and Crystallization of Toll/Interleukin-1 Receptor (TIR) Domains

    E-print Network

    Tong, Liang

    ) Domains Xiao Tao and Liang Tong Summary Toll-like receptors (TLRs) and interleukin-1 receptor (IL-1R) play, Crystallography, Protein structure and function, Signal transduction, Protein complexes. Toll-like receptors (TLRs Claire E. McCoy and Luke A.J. O'Neill (eds.), Methods in Molecular Biology, Toll-Like Receptors, vol. 517

  12. NEW CARTESIAN GRID METHODS FOR INTERFACE PROBLEMS USING THE FINITE ELEMENT FORMULATION

    E-print Network

    NEW CARTESIAN GRID METHODS FOR INTERFACE PROBLEMS USING THE FINITE ELEMENT FORMULATION ZHILIN LI, TAO LIN, AND XIAOHUI WU Abstract. New finite element methods based on Cartesian triangulations to be second order accurate in the maximum norm. The conforming finite element method has been shown

  13. Identifying Security Bug Reports via Text Mining: An Industrial Case Study Michael Gegick, 2

    E-print Network

    Xie, Tao

    Rotella, 3 Tao Xie 1 Independent, 2 Cisco Systems , 3 North Carolina State University Department of Computer Science mcgegick@gmail.com, protella@cisco.com, xie@csc.ncsu.edu Abstract -- A bug-tracking system on a large Cisco software system with over ten million source lines of code. Among a sample of BRs that Cisco

  14. Probabilistic Joint Feature Selection for Multi-task Learning Vladimir Cherkassky

    E-print Network

    Chandy, John A.

    : txiong@ece.umn.edu. The work was conducted when Tao Xiong was with Siemens Medical Solutions. The Computer Aided Diagnosis and Therapy Group, Siemens Medical Solutions. Email: jinbo.bi@siemens.com The Computer Aided Diagnosis and Therapy Group, Siemens Medical Solutions. Email: bharat.rao@siemens

  15. GLASS OBJECT SEGMENTATION BY LABEL TRANSFER ON JOINT DEPTH AND APPEARANCE MANIFOLDS

    E-print Network

    He, Xuming

    GLASS OBJECT SEGMENTATION BY LABEL TRANSFER ON JOINT DEPTH AND APPEARANCE MANIFOLDS Tao Wang address the glass object localization problem with a RGB- D camera. Our approach uses a nonparametric, data-driven label transfer scheme for local glass boundary estimation. A weighted voting scheme based

  16. Wireless LAN Location-Sensing for Security Applications ptao@ece.rice.edu

    E-print Network

    Wallach, Dan

    Wireless LAN Location-Sensing for Security Applications Ping Tao ptao@ece.rice.edu Algis Rudys arudys@cs.rice.edu Andrew M. Ladd aladd@cs.rice.edu Dan S. Wallach dwallach@cs.rice.edu Department of Electrical and Computer Engineering Department of Computer Science Rice University Houston, TX ABSTRACT

  17. Email: yaohang@cs.odu.edu 200 Drummond Place Apt. A3, Norfolk, VA 23507

    E-print Network

    Li, Yaohang

    Li, N. D. Arnold, C. E.M. Strauss, A. J. Bordner, Y. Tian, X. Tao, T. C. PAPERS Schulthess, A. Gorin Generator," submitted to Mathematics and Computers in Simulation, 2010. [14]Yaohang Li, I. Rata, S. Chiu, E(5): 1859-1869, 2010. [12]Yaohang Li, V. A. Protopopescu, N. Arnold, X. Zhang, A. Gorin, "Hybrid Parallel

  18. A 10 year climatology of Arctic cloud fraction and radiative forcing at Barrow, Alaska

    E-print Network

    Shupe, Matthew

    studies, we find that LW CRF does not change over the Arctic regions significantly, but NET CRFs change, doi:10.1029/2009JD013489. 1. Introduction [2] The Arctic plays a major role in global climate through coupled climate model simu- lations of presentday climate is found in the Arctic region [Gates, 1992; Tao

  19. IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS 1 A Unified Approach to Streamline Selection and

    E-print Network

    Wang, Chaoli

    Selection and Viewpoint Selection for 3D Flow Visualization Jun Tao, Student Member, IEEE, Jun Ma, Student scien- tific and engineering disciplines such as climate model- ing, turbulent combustion streamline pool for effective display. Streamline seeding for 2D and 3D vector fields has been well studied

  20. Lipreading Approach for Isolated Digits Recognition under Whisper and Neutral Speech

    E-print Network

    Busso, Carlos

    Lipreading Approach for Isolated Digits Recognition under Whisper and Neutral Speech Fei Tao@utdallas.edu Abstract Whisper is a speech production mode normally used to protect confidential information. Given the differences in the acous- tic domain, the performance of automatic speech recognition (ASR) systems decreases

  1. MUSIC GENRE CLASSIFICATION WITH TAXONOMY School of Computer Science

    E-print Network

    Li, Tao

    MUSIC GENRE CLASSIFICATION WITH TAXONOMY Tao Li School of Computer Science Florida International Rochester, NY, 14627 ABSTRACT Automatic music genre classification is a fundamental compo- nent of music with the emergence of digital music on the Internet. Although consider- able research has been conducted in automatic

  2. Ultra-tightly Coupled GPS/Vehicle Sensor Integration for Land Vehicle Navigation

    E-print Network

    Calgary, University of

    Ultra-tightly Coupled GPS/Vehicle Sensor Integration for Land Vehicle Navigation TAO LI, MARK G, and attitude information. This paper investigates an ultra-tight integration strategy to fuse GPS and a vehicle vehicles can be used to further improve navigation accuracy and system redun- dancy [16]. To integrate

  3. NREL is a national laboratory of the U.S. Department of Energy Office of Energy Efficiency & Renewable Energy

    E-print Network

    & Renewable Energy Operated by the Alliance for Sustainable Energy, LLC. This report is available at no cost from the National Renewable Energy Laboratory (NREL) at www.nrel.gov/publications. Contract No. DE-AC36 to Hydrocarbons R. Davis, L. Tao, E.C.D. Tan, M.J. Biddy, G.T. Beckham, and C. Scarlata National Renewable Energy

  4. Dual Sentiment Analysis: Considering Two Sides of One Review

    E-print Network

    Zong, Chengqing

    available on the Internet, sentiment analysis and opinion mining, as a special text mining task for determin or nega- tive) of a given text. The general practice in sentiment classi- fication follows the techniques, Qianmu Li, Yong Qi, and Tao Li Abstract--Bag-of-words (BOW) is now the most popular way to model text

  5. Fungal inoculation and methyl jasmonate application induce highly variable terpene accumulation in Norway spruce

    E-print Network

    in Norway spruce Tao Zhao 1, Paal Krokene 2, Niklas Björklund 3, Nadir Erbilgin 4 , Erik Christiansen 2 Bo healthy forests. With the aims of characterizing the defensive chemical induction in Norway spruce Picea abies and demonstrating its ecological function to spruce bark beetle Ips typographus, we measured

  6. Factors affecting selenium bioconcentration at the base of aquatic food webs

    E-print Network

    Factors affecting selenium bioconcentration at the base of aquatic food webs by Tao Eastham B: Report No: Master of Resource Management 630 Title: Factors affecting selenium bioconcentration Management Date Defended/Approved: August 14, 2015 #12;iii Abstract Selenium is a naturally occurring element

  7. UnitPlus: Assisting Developer Testing in Eclipse Yoonki Song1

    E-print Network

    Robillard, Martin

    UnitPlus: Assisting Developer Testing in Eclipse Yoonki Song1 Suresh Thummalapenta2 Tao Xie3}@ncsu.edu, 3 xie@csc.ncsu.edu ABSTRACT In the software development life cycle, unit testing is an im- portant phase that helps in early detection of bugs. A unit test case consists of two parts: a test input, which

  8. Appears in Proc. 20th European Conference on Object-Oriented Programming (ECOOP 2006), Nantes, France Augmenting Automatically Generated Unit-Test Suites

    E-print Network

    Xie, Tao

    , France Augmenting Automatically Generated Unit-Test Suites with Regression Oracle Checking Tao Xie. A test case consists of two parts: a test input to exercise the program under test and a test oracle to check the correctness of the test execution. A test oracle is often in the form of executable assertions

  9. Tool-Assisted Unit-Test Generation and Selection Based on Operational Abstractions

    E-print Network

    Xie, Tao

    Tool-Assisted Unit-Test Generation and Selection Based on Operational Abstractions Tao Xie1 of Washington, Seattle, WA 98105 Abstract. Unit testing, a common step in software development, presents a chal- lenge. When produced manually, unit test suites are often insufficient to identify defects. The main

  10. Automatically Identifying Special and Common Unit Tests for Object-Oriented Programs

    E-print Network

    Xie, Tao

    Automatically Identifying Special and Common Unit Tests for Object-Oriented Programs Tao Xie@cs.washington.edu Abstract Developers often create common tests and special tests, which exercise common behaviors and special behaviors of the class under test, respectively. Although manually created tests are valuable

  11. Gene expression networks underlying retinoic acidinduced differentiation of acute promyelocytic leukemia cells

    E-print Network

    Tian, Weidong

    promyelocytic leukemia cells Ting-Xi Liu, Ji-Wang Zhang, Jiong Tao, Ruo-Bo Zhang, Qing-Hua Zhang, Chun-Jun Zhao promyelo- cytic leukemia (APL) cells, the gene expression patterns in the APL cell line NB4 before Introduction Acute promyelocytic leukemia (APL) is an interesting model in the study of human cancer because

  12. Lithographically defined uniform worm-shaped polymeric nanoparticles This article has been downloaded from IOPscience. Please scroll down to see the full text article.

    E-print Network

    Hu, Wenchuang "Walter"

    Lithographically defined uniform worm-shaped polymeric nanoparticles This article has been.1088/0957-4484/21/9/095301 Lithographically defined uniform worm-shaped polymeric nanoparticles L Tao1 , X M Zhao1 , J M Gao2 and W Hu1,3 1 combined with photolithography on a bi-layer polymer setup to define nano-worms laterally in nano

  13. MATHEMATICAL PERSPECTIVES BULLETIN (New Series) OF THE

    E-print Network

    Tomforde, Mark

    , philosophy, history, scholarship, or practice of mathematics); (xiii) Rigorous mathematics (with all detailsMATHEMATICAL PERSPECTIVES BULLETIN (New Series) OF THE AMERICAN MATHEMATICAL SOCIETY Volume 44, 2007 WHAT IS GOOD MATHEMATICS? TERENCE TAO Abstract. Some personal thoughts and opinions on what "good

  14. Sparsity in Astrophysics: from Wavelets to Compressed Sensing

    E-print Network

    Starck, Jean-Luc

    Sparsity in Astrophysics: from Wavelets to Compressed Sensing Jean-Luc Starck CEA, IRFU, Service d: From Wavelets to Compressed Sensing #12;Where M is the mask: M(i,j) = 0 ==> missing data M(i,j) = 1/reconstruction operator: #12;Compressed Sensing * E. Candès and T. Tao, "Near Optimal Signal Recovery From Random

  15. The Taiwanese-American Occultation Survey Project Stellar Variability. II. Detection of 15 Variable Stars

    NASA Astrophysics Data System (ADS)

    Mondal, S.; Lin, C. C.; Chen, W. P.; Zhang, Z.-W.; Alcock, C.; Axelrod, T.; Bianco, F. B.; Byun, Y.-I.; Coehlo, N. K.; Cook, K. H.; Dave, R.; Kim, D.-W.; King, S.-K.; Lee, T.; Lehner, M. J.; Lin, H.-C.; Marshall, S. L.; Protopapas, P.; Rice, J. A.; Schwamb, M. E.; Wang, J.-H.; Wang, S.-Y.; Wen, C.-Y.

    2010-05-01

    The Taiwanese-American Occultation Survey (TAOS) project has collected more than a billion photometric measurements since 2005 January. These sky survey data—covering timescales from a fraction of a second to a few hundred days—are a useful source to study stellar variability. A total of 167 star fields, mostly along the ecliptic plane, have been selected for photometric monitoring with the TAOS telescopes. This paper presents our initial analysis of a search for periodic variable stars from the time-series TAOS data on one particular TAOS field, No. 151 (R.A. = 17h30m6.s7, decl. = 27°17'30'', J2000), which had been observed over 47 epochs in 2005. A total of 81 candidate variables are identified in the 3 deg2 field, with magnitudes in the range 8 < R < 16. On the basis of the periodicity and shape of the light curves, 29 variables, 15 of which were previously unknown, are classified as RR Lyrae, Cepheid, ? Scuti, SX Phonencis, semi-regular, and eclipsing binaries.

  16. This document contains the draft version of the following paper: T. Peng and S.K. Gupta. Algorithms for generating adaptive projection patterns for

    E-print Network

    Gupta, Satyandra K.

    Projection Patterns for 3-D Shape Measurement Tao Peng Satyandra K. Gupta Abstract Point cloud construction fringe patterns. Keywords: 3-D shape measurement; point cloud; digital fringe projection; adaptive pro for generating adaptive projection patterns for 3-D shape measurement. ASME Journal of Computing and Information

  17. ION ITM 2011, Session B3, San Diego, CA, 24-26 January 2011 1 of 12 Real-time Ultra-tight Integration of GPS L1/L2C

    E-print Network

    Calgary, University of

    -tight Integration of GPS L1/L2C and Vehicle Sensors Tao Li, Mark G. Petovello and G. Lachapelle Position, Location vehicle navigation. Dr. Mark Petovello is an Associate Professor in the Position, Location And Navigation & Wang 2006, Pany et al. 2005, Landis et al. 2006, Ohlmeyer 2066, Petovello et al 2008, Soloviev et al

  18. Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. Modeling of Lattice Parameter in the Ni-Al System

    E-print Network

    Chen, Long-Qing

    Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. Modeling of Lattice Parameter in the Ni-Al System Tao Wang; Jingzhi Zhu; Rebecca A MacKay; Long #12;Reproduced with permission of the copyright owner. Further reproduction prohibited without

  19. IntClust: A Software Package for Clustering Replicated Microarray Data

    E-print Network

    Li, Tao

    Introduction Gene-expression microarray technology is a widely applied high-throughput means for understandingIntClust: A Software Package for Clustering Replicated Microarray Data Wei Peng and Tao Li School analysis. By utilizing interval data for representing replicated microarray data, IntClust is able to take

  20. Energy Efficient Algorithms for the RFID Estimation Problem

    E-print Network

    Chen, Shigang

    applications, including inventory control, object tracking, and supply chain manage- ment. RFID tags (eachEnergy Efficient Algorithms for the RFID Estimation Problem Tao Li Samuel Wu§ Shigang Chen Mark Policy Research §Department of Statistics University of Florida, Gainesville, FL 32611, USA Abstract--RFID