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Sample records for tipos textuales del

  1. The Textual Puzzle Technique.

    ERIC Educational Resources Information Center

    Lanier, Dorothy C.

    Textual puzzles may be used in freshman composition or introduction to writing courses to emphasize word order and subject-predicate agreement. These sentence puzzles demonstrate that the English language depends primarily upon word order to convey meaning, and assist students to avoid blending statement and question word order in their sentences…

  2. Textual Design and Student Learning.

    ERIC Educational Resources Information Center

    Parer, Michael S.

    A study was conducted to examine the relationships of four areas of textual design factors that are relevant to external students' learning as they use their course study guides: the micro and macro textual features, the linguistics, and the instructional design elements. Twelve external students from two units at the Gippsland Institute were…

  3. An Approach to Textual Steganography

    NASA Astrophysics Data System (ADS)

    Morran, Michael; Weir, George R. S.

    Textual steganography is a means of concealing an encoded message within text. The appeal in such a system is its potential for hiding the fact that encoding is taking place. The failure to hide the presence of encoding is a form of information leakage and an inherent risk since it suggests that there is important or valuable information in transit. This is considered a major limitation of existing cryptographic techniques as applied to secure information transfer. In this paper, we describe an experimental system that we have developed as a test bed for textual steganography. This system allows us to explore the application of part of speech tagging, word sense disambiguation and synonym replacement as component strategies for textual steganography.

  4. La busqueda textual por computadora (Textual Search by Computer)

    ERIC Educational Resources Information Center

    Davison, Ned J.

    1977-01-01

    Describes the use of the computer program EDIT for textual searches to locate a certain programmed word or word root. In the examples explained here, the vocabulary search is performed on poetry and allows examination of the metaphorical and conceptual poetic atmosphere achieved through word use. (Text is in Spanish.) (CHK)

  5. Cultural Backgrounds and Textual Appropriation

    ERIC Educational Resources Information Center

    Shi, Ling

    2006-01-01

    This study examines interviews with 46 undergraduates to explore if participants with differing language and cultural backgrounds view plagiarism or textual appropriation primarily as a) a language problem because of a lack of words of one's own, or b) a cultural challenge as a result of either some first language (L1) cultural training to…

  6. [Herbalogical textual research of Wuyi].

    PubMed

    Zhao, Hai-liang; Zhang, Rui-xian

    2015-11-01

    Wuyi is one of the Chinese medicine recorded in Shennong's Herbal Classic and many other herbal books during the long history period. Up to now, Wuyi is still an important medicine used for insecticidal and removing food retention. Recent researches indicated that Wuyi also had the function of anti-malaria and treating herpetic simplex keratitis. Therefore, Wuyi had notable value on clinic and development of new medicine. The herbalogical textual research on Wuyi was conducted through investigation of the literature of materia medica during the long historical period from Han Dynasty. It was demonstrated by this work that the original plants of Wuyi include Ulmus macrocarpa Hance and Hemiptelea davidii (Hance) Planch, in which, U. macrocarpa was the quality specie. U. pumila was the false specie which cause confusing. The medicine Wuyi was the processed product made from the nutlet of the plants through fermentation with other additive agents. PMID:27097433

  7. Universal lossless compression algorithm for textual images

    NASA Astrophysics Data System (ADS)

    al Zahir, Saif

    2012-03-01

    In recent years, an unparalleled volume of textual information has been transported over the Internet via email, chatting, blogging, tweeting, digital libraries, and information retrieval systems. As the volume of text data has now exceeded 40% of the total volume of traffic on the Internet, compressing textual data becomes imperative. Many sophisticated algorithms were introduced and employed for this purpose including Huffman encoding, arithmetic encoding, the Ziv-Lempel family, Dynamic Markov Compression, and Burrow-Wheeler Transform. My research presents novel universal algorithm for compressing textual images. The algorithm comprises two parts: 1. a universal fixed-to-variable codebook; and 2. our row and column elimination coding scheme. Simulation results on a large number of Arabic, Persian, and Hebrew textual images show that this algorithm has a compression ratio of nearly 87%, which exceeds published results including JBIG2.

  8. Introducing Textual Criticisn to Ancient History Students

    ERIC Educational Resources Information Center

    Whitehorne, J. E. G.

    1975-01-01

    Describes an experiment made to illustrate to Ancient History students the value of textual criticism and the problems involved in transmitting a text through the centuries by means of imperfectly copied and preserved manuscripts. (CHK)

  9. Textual Enhancement of Input: Issues and Possibilities

    ERIC Educational Resources Information Center

    Han, ZhaoHong; Park, Eun Sung; Combs, Charles

    2008-01-01

    The input enhancement hypothesis proposed by Sharwood Smith (1991, 1993) has stimulated considerable research over the last 15 years. This article reviews the research on textual enhancement of input (TE), an area where the majority of input enhancement studies have aggregated. Methodological idiosyncrasies are the norm of this body of research.…

  10. Does textual feedback hinder spoken interaction in natural language?

    PubMed

    Le Bigot, Ludovic; Terrier, Patrice; Jamet, Eric; Botherel, Valerie; Rouet, Jean-Francois

    2010-01-01

    The aim of the study was to determine the influence of textual feedback on the content and outcome of spoken interaction with a natural language dialogue system. More specifically, the assumption that textual feedback could disrupt spoken interaction was tested in a human-computer dialogue situation. In total, 48 adult participants, familiar with the system, had to find restaurants based on simple or difficult scenarios using a real natural language service system in a speech-only (phone), speech plus textual dialogue history (multimodal) or text-only (web) modality. The linguistic contents of the dialogues differed as a function of modality, but were similar whether the textual feedback was included in the spoken condition or not. These results add to burgeoning research efforts on multimodal feedback, in suggesting that textual feedback may have little or no detrimental effect on information searching with a real system. STATEMENT OF RELEVANCE: The results suggest that adding textual feedback to interfaces for human-computer dialogue could enhance spoken interaction rather than create interference. The literature currently suggests that adding textual feedback to tasks that depend on the visual sense benefits human-computer interaction. The addition of textual output when the spoken modality is heavily taxed by the task was investigated. PMID:20069480

  11. Permeable Textual Discussion in Tracked Language Arts Classrooms

    ERIC Educational Resources Information Center

    Gritter, Kristine

    2012-01-01

    Permeable textual discussion occurs when the unofficial texts and discursive practices and personal histories that are already recognized and valued in students' cultures are scaffolds to academically sanctioned literacies. Ideally, permeable textual discussions are safe havens where students' identities (racial, gender, world views) are…

  12. Essjay's "Ethos": Rethinking Textual Origins and Intellectual Property

    ERIC Educational Resources Information Center

    Brown, James J., Jr.

    2009-01-01

    Discussions of intellectual property are often the focus of rhetoric and composition research, and the question of textual origins grounds these discussions. Through an examination of Wikipedia, the online encyclopedia anyone can edit, this essay addresses disciplinary concerns about textual origins and intellectual property through a discussion…

  13. Prototype for remotely shared textual workspaces

    SciTech Connect

    Abdel-Wahab, H.M.; Guan, S.U.; Nievergelt, J.

    1987-01-01

    Computer-based collaboration between geographically dispersed users is still limited primarily to electronic mail and file transfer, but there is increasing interest in computer support for real-time interaction between remote users. The problem of implementing remotely shared workspaces, which allow users to operate simultaneously on the same objects, is of broad interest. Our objective is to show textual workspaces that allow real-time collaboration can be implemented efficiently by using existing operating systems and communications primitives. This paper documents our experiences in implementing a prototype under Berkeley UNIX, using the programming language C, and Berkeley Interprocess Communication facilities. The authors describe design alternatives that take into account the communications bandwidth between the different sites of the network, and they introduce an efficient protocol that regulates user access to the shared workspace.

  14. [Achievement of Qimin Yaoshu in area of herbalogical textual research].

    PubMed

    Zhao, Hai-Liang; Zhang, Rui-Xian

    2015-11-01

    The achievement of Qimin Yaoshu in the area of herbalogical textual research was illustrated in this paper. Qimin Yaoshu quoted and keeped many contents from ancient agriculture books related in herbalogical literature. It also recorded the information of lots of tropical and subtropical plants. The author bringed forwarded many experiences indistinguishing plants and clarified some long last confused or wrong opinions. The studying philosophy and methods of the authors gave us much enlightenment in our herbalogical textual research. It should be taken into account when the herbalogical textual research was carried out. PMID:27071275

  15. Textual emotion recognition for enhancing enterprise computing

    NASA Astrophysics Data System (ADS)

    Quan, Changqin; Ren, Fuji

    2016-05-01

    The growing interest in affective computing (AC) brings a lot of valuable research topics that can meet different application demands in enterprise systems. The present study explores a sub area of AC techniques - textual emotion recognition for enhancing enterprise computing. Multi-label emotion recognition in text is able to provide a more comprehensive understanding of emotions than single label emotion recognition. A representation of 'emotion state in text' is proposed to encompass the multidimensional emotions in text. It ensures the description in a formal way of the configurations of basic emotions as well as of the relations between them. Our method allows recognition of the emotions for the words bear indirect emotions, emotion ambiguity and multiple emotions. We further investigate the effect of word order for emotional expression by comparing the performances of bag-of-words model and sequence model for multi-label sentence emotion recognition. The experiments show that the classification results under sequence model are better than under bag-of-words model. And homogeneous Markov model showed promising results of multi-label sentence emotion recognition. This emotion recognition system is able to provide a convenient way to acquire valuable emotion information and to improve enterprise competitive ability in many aspects.

  16. A Computational Approach to Qualitative Analysis in Large Textual Datasets

    PubMed Central

    Evans, Michael S.

    2014-01-01

    In this paper I introduce computational techniques to extend qualitative analysis into the study of large textual datasets. I demonstrate these techniques by using probabilistic topic modeling to analyze a broad sample of 14,952 documents published in major American newspapers from 1980 through 2012. I show how computational data mining techniques can identify and evaluate the significance of qualitatively distinct subjects of discussion across a wide range of public discourse. I also show how examining large textual datasets with computational methods can overcome methodological limitations of conventional qualitative methods, such as how to measure the impact of particular cases on broader discourse, how to validate substantive inferences from small samples of textual data, and how to determine if identified cases are part of a consistent temporal pattern. PMID:24498398

  17. The visual analysis of textual information: Browsing large document sets

    SciTech Connect

    Thomas, J.; Pennock, K.; Fiegel, T.; Wise, J.; Pottier, M.; Schur, A.; Crow, V.; Lantrip, D.

    1995-05-01

    Visualization tools have been invaluable in the process of scientific discovery by providing researchers with insights gained through graphical tools and techniques. At PNL, the Multidimensional Visualization and Advanced Browsing (MVAB) project is extending visualization technology to the problems of intelligence analysis of textual documents by creating spatial representations of textual information. By representing an entire corpus of documents as points in a coordinate space of two or more dimensions, the tools developed by the MVAB team give the analyst the ability to quickly browse the entire document base and determine relationships among documents and publication patterns not readily discernible through traditional lexical means.

  18. Reclaiming Literacies: Competing Textual Practices in a Digital Higher Education

    ERIC Educational Resources Information Center

    Lea, Mary R.

    2013-01-01

    This essay examines the implications of the ubiquitous use of the term "digital literacies" in higher education and its increasing alignment with institutional and organisational imperatives. It suggests that the term has been stripped of its provenance and association with disciplinary knowledge production and textual practice. Instead…

  19. Textual Analyses of Nutrition Messages on Prime Time Television.

    ERIC Educational Resources Information Center

    Wadsworth, Laurie A.; Berenbaum, Shawna

    2001-01-01

    Using textual analysis of 805 incidents in 10 television programs and surrounding commercials, foods portrayed were compared with nutrition guidelines. Foods tended to be higher in fat and lower in fiber, and food portrayals had social and psychological meanings. Adverse health effects of foods low in nutrients were not depicted. (Contains 57…

  20. Marking Importance in Lectures: Interactive and Textual Orientation

    ERIC Educational Resources Information Center

    Deroey, Katrien L. B.

    2015-01-01

    This paper provides a comprehensive overview of lexicogrammatical markers of important lecture points and proposes a classification in terms of their interactive and textual orientation. The importance markers were extracted from the British Academic Spoken English corpus using corpus-driven and corpus-based methods. The classification is based on…

  1. Textual appropriation in engineering master's theses: a preliminary study.

    PubMed

    Eckel, Edward J

    2011-09-01

    In the thesis literature review, an engineering graduate student is expected to place original research in the context of previous work by other researchers. However, for some students, particularly those for whom English is a second language, the literature review may be a mixture of original writing and verbatim source text appropriated without quotations. Such problematic use of source material leaves students vulnerable to an accusation of plagiarism, which carries severe consequences. Is such textual appropriation common in engineering master's writing? Furthermore, what, if anything, can be concluded when two texts have been found to have textual material in common? Do existing definitions of plagiarism provide a sufficient framework for determining if an instance of copying is transgressive or not? In a preliminary attempt to answer these questions, text strings from a random sample of 100 engineering master's theses from the ProQuest Dissertations and Theses database were searched for appropriated verbatim source text using the Google search engine. The results suggest that textual borrowing may indeed be a common feature of the master's engineering literature review, raising questions about the ability of graduate students to synthesize the literature. The study also illustrates the difficulties of making a determination of plagiarism based on simple textual similarity. A context-specific approach is recommended when dealing with any instance of apparent copying. PMID:20521174

  2. Voice Construction, Assessment, and Extra-Textual Identity

    ERIC Educational Resources Information Center

    Tardy, Christine M.

    2012-01-01

    The concept of voice has long attracted the attention of teachers, but more recently has also been the focus of a growing body of research aiming to understand voice as self-representation in writing. Adopting a socio-cultural orientation to voice, studies have revealed much about how textual choices are used by readers to build images of…

  3. Science Journalism under Scrutiny: A Textual Analysis of "Science Times."

    ERIC Educational Resources Information Center

    Fursich, Elfriede; Lester, E. P.

    1996-01-01

    Uses a new cultural framework for the analysis of science popularization for textual analysis of the "Scientist at Work" column of the "New York Times." Shows that, although the journalists try to demystify the scientific enterprise, they juxtapose "pure" science against other dimensions of scientific work, thus reinforcing the notion of…

  4. Legitimate Textual Borrowing: Direct Quotation in L2 Student Writing

    ERIC Educational Resources Information Center

    Petric, Bojana

    2012-01-01

    Using textual analysis and interviews with student writers, this study aims to provide an insight into second language students' use of direct quotations in their MA theses by comparing direct quotations in high-rated and low-rated Master's theses, and by exploring student writers' own motivations to quote directly from sources. The corpus…

  5. Multilingual Knowledge-Based Concept Recognition in Textual Data

    NASA Astrophysics Data System (ADS)

    Schierle, Martin; Trabold, Daniel

    With respect to the increasing volume of textual data which is available through digital resources today, the identification of the main concepts in those texts becomes increasingly important and can be seen as a vital step in the analysis of unstructured information.

  6. ARD -- A Textual Language for Describing Regions within a Data Array

    NASA Astrophysics Data System (ADS)

    Berry, D. S.

    The ARD (ASCII Region Definition) system provides a textual language for describing regions within a data array, together with software for converting a textual description into a pixel mask, or plotting it on a graphics device. The textual language is based on a set of keywords identifying simple shapes (boxes, circles, lines, etc.). These keywords can be combined together using Boolean-style operators (AND, OR, NOT, etc.) to create more complex shapes. Data arrays can be multi-dimensional.

  7. Using Textual Prompts to Teach Mands for Information Using "Who?".

    PubMed

    Shillingsburg, M Alice; Gayman, Cassondra M; Walton, William

    2016-06-01

    Recent research on teaching mands for information to children with language deficits has focused on manipulating establishing operations (EOs). However, only a few of those studies have programmed both EO conditions (in which information is needed) and abolishing operation (AO) conditions (in which information has already been provided) to ensure functional use of the mand for information. Shillingsburg, Bowen, Valentino, and Pierce (Journal of Applied Behavior Analysis, 47, 136-150, 2014) provided a successful demonstration of differential responding between EO and AO conditions demonstrating control of the response by the relevant EO. Echoic prompts resulted in successful mands for information "Who?" One limitation of this study was that the participants did not re-issue the initial mand upon approaching the named adult to retrieve the item. This may be problematic in the natural environment as it is unlikely that the named adult would know what the child was looking for. The current study sought to replicate and expand previous research by using textual prompts to teach the mand "Who?" in four children diagnosed with autism (Phase 1) and by requiring the mand for the item be re-issued upon approaching the named adult (Phase 2). Textual prompts resulted in differential use of the mand for information during EO and AO conditions for all of the participants. Additionally, three of the four participants who did not re-issue the mand to the named adult during the Phase 2 baseline did so following the intervention. Overall, results support the use of textual prompts to teach mands for information to children with autism. PMID:27606218

  8. Computer-Assisted Search Of Large Textual Data Bases

    NASA Technical Reports Server (NTRS)

    Driscoll, James R.

    1995-01-01

    "QA" denotes high-speed computer system for searching diverse collections of documents including (but not limited to) technical reference manuals, legal documents, medical documents, news releases, and patents. Incorporates previously available and emerging information-retrieval technology to help user intelligently and rapidly locate information found in large textual data bases. Technology includes provision for inquiries in natural language; statistical ranking of retrieved information; artificial-intelligence implementation of semantics, in which "surface level" knowledge found in text used to improve ranking of retrieved information; and relevance feedback, in which user's judgements of relevance of some retrieved documents used automatically to modify search for further information.

  9. Textual standardization and the DSM-5 "common language".

    PubMed

    Kelly, Patty A

    2014-06-01

    In February 2010, the American Psychiatric Association (APA) launched their DSM-5 website with details about the development of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). The APA invited "the general public" to review the draft diagnostic criteria and provide written comments and suggestions. This revision marks the first time the APA has solicited public review of their diagnostic manual. This article analyzes reported speech on the DSM-5 draft diagnostic criteria for the classification Posttraumatic Stress Disorder. It demonstrates how textual standardization facilitates the cultural portability of the DSM-5 diagnostic criteria such that a community of speakers beyond the borders of the APA come to be seen as exemplary speakers, writers, and revisers of the professional style. Furthermore, analysis shows how co-authoring practices recontextualize the "voice" and persona of putative patient reported speech on Criterion D2. As a consequence of textual standardization, spoken discourse becomes recontextualized as the product of scientific inquiry and the organization of psychiatric knowledge. PMID:24682628

  10. The Effect of Different Textual Narrations on Students' Explanations at the Submicroscopic Level in Chemistry

    ERIC Educational Resources Information Center

    Al-Balushi, Sulaiman M.

    2013-01-01

    The effect of different textual versions (macroscopic (control), submicroscopic, and guided imagery) of the explanation of a chemical phenomenon on students' submicroscopic explanation of a related phenomenon was examined. The sample included 152 pre-service science teachers. The three textual versions of the explanation were distributed randomly…

  11. The Effects of Textual Enhancement Type on L2 Form Recognition and Reading Comprehension in Spanish

    ERIC Educational Resources Information Center

    LaBrozzi, Ryan M.

    2016-01-01

    Previous research investigating the effectiveness of textual enhancement as a tool to draw adult second language (L2) learners' attention to the targeted linguistic form has consistently produced mixed results. This article examines how L2 form recognition and reading comprehension are affected by different types of textual enhancement.…

  12. The Target of the Question: A Taxonomy of Textual Features for Cambridge University "O" Levels English

    ERIC Educational Resources Information Center

    Benjamin, Shanti Isabelle

    2015-01-01

    This study investigates the typical textual features that are most frequently targeted in short-answer reading comprehension questions of the Cambridge University "O" Level English Paper 2. Test writers' awareness of how textual features impact on understanding of meanings in text decisions will determine to great extent their decisions…

  13. Une Analyse automatique en syntaxe textuelle (An Automated Analysis of Textual Syntax). Publication K-5.

    ERIC Educational Resources Information Center

    Ladouceur, Jacques

    This study reports the use of automated textual analysis on a French novel. An introductory section chronicles the history of artificial intelligence, focusing on its use with natural languages, and discusses its application to textual syntax. The first chapter examines computational linguistics in greater detail, looking at its relationship to…

  14. The Use of Textual Memorisation in Foreign Language Learning: Hearing the Chinese Learner and Teacher Voice

    ERIC Educational Resources Information Center

    Yu, Xia

    2014-01-01

    Textual memorisation is a widely used yet underexplored language practice in foreign language teaching and learning in China. The research addresses the need for a comprehensive and in-depth understanding of the practices and beliefs of Chinese learners regarding the use of textual memorisation in foreign language learning. This article reports on…

  15. Textual Input Enhancement for Vowel Blindness: A Study with Arabic ESL Learners

    ERIC Educational Resources Information Center

    Alsadoon, Reem; Heift, Trude

    2015-01-01

    This study explores the impact of textual input enhancement on the noticing and intake of English vowels by Arabic L2 learners of English. Arabic L1 speakers are known to experience "vowel blindness," commonly defined as a difficulty in the textual decoding and encoding of English vowels due to an insufficient decoding of the word form.…

  16. The Empirical Derivation of Equations for Predicting Subjective Textual Information. Final Report.

    ERIC Educational Resources Information Center

    Kauffman, Dan; And Others

    A study was made to derive an equation for predicting the "subjective" textual information contained in a text of material written in the English language. Specifically, this investigation describes, by a mathematical equation, the relationship between the "subjective" information content of written textual material and the relative number of…

  17. Atlas del Genoma del Cáncer: Antecedentes

    Cancer.gov

    El Atlas del Genoma del Cáncer es una iniciativa de los Institutos Nacionales de la Salud (NIH) para crear mapas multidimensionales completos de los cambios genómicos clave en los tipos y subtipos principales de cáncer.

  18. Frequency shifting approach towards textual transcription of heartbeat sounds.

    PubMed

    Arvin, Farshad; Doraisamy, Shyamala; Safar Khorasani, Ehsan

    2011-01-01

    Auscultation is an approach for diagnosing many cardiovascular problems. Automatic analysis of heartbeat sounds and extraction of its audio features can assist physicians towards diagnosing diseases. Textual transcription allows recording a continuous heart sound stream using a text format which can be stored in very small memory in comparison with other audio formats. In addition, a text-based data allows applying indexing and searching techniques to access to the critical events. Hence, the transcribed heartbeat sounds provides useful information to monitor the behavior of a patient for the long duration of time. This paper proposes a frequency shifting method in order to improve the performance of the transcription. The main objective of this study is to transfer the heartbeat sounds to the music domain. The proposed technique is tested with 100 samples which were recorded from different heart diseases categories. The observed results show that, the proposed shifting method significantly improves the performance of the transcription. PMID:21970368

  19. Analysis of Financial Markets' Fluctuation by Textual Information

    NASA Astrophysics Data System (ADS)

    Izumi, Kiyoshi; Goto, Takashi; Matsui, Tohgoroh

    In this study, we proposed a new text-mining methods for long-term market analysis. Using our method, we analyzed monthly price data of financial markets; Japanese government bond market, Japanese stock market, and the yen-dollar market. First we extracted feature vectors from monthly reports of Bank of Japan. Then, trends of each market were estimated by regression analysis using the feature vectors. As a result, determination coefficients were over 75%, and market trends were explained well by the information that was extracted from textual data. We compared the predictive power of our method among the markets. As a result, the method could estimate JGB market best and the stock market is the second.

  20. The Textuality of Stress: Drawing between Scientific and Everyday Accounting.

    PubMed

    Brown, S D

    1996-04-01

    Stress is a key term in health psychology, marking both conceptual possibilities and legislative failures. Rather than add a further global theory of stress, the term is examined as it operates in numerous kinds of practices. Drawing on qualitative material from varying sources I place emphasis on the role of concern and understanding in the definition of stress as the matter at hand. A discursive approach is used to worry the opposition of scientific and cultural practice in stress research and point instead to the notion of specific problematizations that appear in the rich fabric of the term's definition and description. I propose that attention to the details of a textuality of stress marks a step towards a 'modest' health psychology. PMID:22011703

  1. Vacunas contra los virus del papiloma humano

    Cancer.gov

    Una hoja informativa acerca de las vacunas contra los virus del papiloma humano (VPH) para prevenir infecciones con ciertos tipos de VPH, los cuales son la causa principal del cáncer de cuello del útero o cérvix.

  2. The Text's the Thing: Using (Neglected) Issues of Textual Scholarship to Help Students Reimagine Shakespeare

    ERIC Educational Resources Information Center

    Parsons, Scott

    2009-01-01

    Do individuals know what words Shakespeare actually wrote? Exploring these issues can yield dramatic interest. With references to Shakespeare's Quartos and Folios, the author examines key textual issues and discrepancies in classroom studies of "Hamlet." (Contains 8 notes.)

  3. The Army as Textual Community: Exploring Mismatches in the Concepts of Attribution, Appropriation, and Shared Goals

    ERIC Educational Resources Information Center

    Anson, Chris; Neely, Shawn

    2010-01-01

    This webtext examines the practices of authorial attribution in textual production in higher education (where notions of individual authorship and intellectual property prevail, particularly at military academies) and in the military (which has a more public conception of authorship).

  4. Textual Analysis and Data Mining: An Interpreting Research on Nursing.

    PubMed

    De Caro, W; Mitello, L; Marucci, A R; Lancia, L; Sansoni, J

    2016-01-01

    Every day there is a data explosion on the web. In 2013, 5 exabytes of content were created each day. Every hour internet networks carries a quantity of texts equivalent to twenty billion books. For idea Iit is a huge mass of information on the linguistic behavior of people and society that was unthinkable until a few years ago. It is an opportunity for valuable analysis for understanding social phenomena, also in nursing and health care sector.This poster shows the the steps of an idealy strategy for textual statistical analysis and the process of extracting useful information about health care, referring expecially nursing care from journal and web information. We show the potential of web tools of Text Mining applications (DTM, Wordle, Voyant Tools, Taltac 2.10, Treecloud and other web 2.0 app) analyzing text data and information extraction about sentiment, perception, scientific activites and visibility of nursing. This specific analysis is conduct analyzing "Repubblica", first newspaper in Italy (years of analisys: 2012-14) and one italian scientific nursing journal (years: 2012-14). PMID:27332424

  5. Gross's anatomy: textual politics in science/biology education research

    NASA Astrophysics Data System (ADS)

    Reis, Giuliano

    2009-12-01

    In approaching how the grotesque is—or should be—situated within contemporary science (biology) education practices, Weinstein and Broda undertake a passionate reclaim of an education that is at the same time scientific, critical, and liberatory. However legitimate, their work offers more than they probably could have anticipated: It exemplifies how the textual structure of a research article can be such as to "tip-off" readers about how it is supposed to be understood. In this way, what one learns from reading the manuscript is grounded on the way the authors examine the data presented. That is, the findings are not intrinsic to the materials collected, but constructed within the analyses that precede/follow the account of each one of the four "specimens" reported. Therefore, the present commentary seeks to re-consider the original study from an alternative perspective, one that challenges its seemingly objective (re)construction of facts by placing emphasis on how the text contains instructions for its own interpretation and validation. Ultimately, the purpose here is to describe and discuss the interpretive and validation work that is done by this discursive mechanism of self-appraisal rather than discredit the two authors' initiative.

  6. Fusion of Laboratory and Textual Data for Investigative Bioforensics

    SciTech Connect

    Webb-Robertson, Bobbie-Jo M.; Corley, Courtney D.; McCue, Lee Ann; Wahl, Karen L.; Kreuzer, Helen W.

    2013-03-10

    Chemical and biological forensic programs focus on the identification of a threat and acquisition of laboratory measurements to determine how a threat agent may have been produced. However, to generate investigative leads, it might also be useful to identify institutions where the same agent has been produced by the same or a very similar process, since the producer of the agent may have learned methods at a university or similar institution. We have developed a Bayesian network framework that fuses hard and soft data sources to assign probability to production practices. It combines the results of laboratory measurements with an automatic text reader to scan scientific literature and rank institutions that had published papers on the agent of interest in order of the probability that the institution has the capability to generate the sample of interest based on laboratory data. We demonstrate the Bayesian network on an example case from microbial forensics, predicting the methods used to produce Bacillus anthracis spores based on mass spectrometric measurements and identifying institutions that have a history of growing Bacillus spores using the same or highly similar methods. We illustrate that the network model can assign a higher posterior probability than expected by random chance to appropriate institutions when trained using only a small set of manually analyzed documents. This is the first example of an automated methodology to integrate experimental and textual data for the purpose of investigative forensics.

  7. Extracting the Textual and Temporal Structure of Supercomputing Logs

    SciTech Connect

    Jain, S; Singh, I; Chandra, A; Zhang, Z; Bronevetsky, G

    2009-05-26

    Supercomputers are prone to frequent faults that adversely affect their performance, reliability and functionality. System logs collected on these systems are a valuable resource of information about their operational status and health. However, their massive size, complexity, and lack of standard format makes it difficult to automatically extract information that can be used to improve system management. In this work we propose a novel method to succinctly represent the contents of supercomputing logs, by using textual clustering to automatically find the syntactic structures of log messages. This information is used to automatically classify messages into semantic groups via an online clustering algorithm. Further, we describe a methodology for using the temporal proximity between groups of log messages to identify correlated events in the system. We apply our proposed methods to two large, publicly available supercomputing logs and show that our technique features nearly perfect accuracy for online log-classification and extracts meaningful structural and temporal message patterns that can be used to improve the accuracy of other log analysis techniques.

  8. [Textual research on the edition of WU Kun's books].

    PubMed

    Wang, Xu-Guang; Lu, Xiang

    2013-03-01

    WU Kun is a famous physician of the Xin'an School. He wrote a 6-volume Yi fang kao (Textual Research on Recipes) in 1584, a 24-volume Wu zhu su wen (Wu's Annotation of Plain Questions) in 1594, a 6-volume Zhen fang liu ji (Six Collections of Acupuncture and Prescription) in 1618 block-printed and funded by CHENG Biao, and a 2-volume Mai yu (Language of Pulse) with writing date unknown. For Yi fang kao, there were 4 editions, including Ming-dynasty block-printed edition, Japanese and Korean block-printed edition, old hand-copied edition and modern printing edition. For Wu zhu su wen, there were 5 editions, Ming-Qing-dynasty block-printed edition, Japanese block-printed edition, old hand-copied edition, photocopy and modern edition. For Zhen fang liu ji, there were Ming-dynasty block-printed edition, hand-copied edition, photocopy and modern edition. Mai yu always was printed together with Yi fang kao, and its editions were same as those of Yi fang kao, except some modern printing edition with Mai yu excluded. PMID:24135480

  9. Experiential Thinking in Creationism—A Textual Analysis

    PubMed Central

    Nieminen, Petteri; Ryökäs, Esko; Mustonen, Anne-Mari

    2015-01-01

    Creationism is a religiously motivated worldview in denial of biological evolution that has been very resistant to change. We performed a textual analysis by examining creationist and pro-evolutionary texts for aspects of “experiential thinking”, a cognitive process different from scientific thought. We observed characteristics of experiential thinking as follows: testimonials (present in 100% of sampled creationist texts), such as quotations, were a major form of proof. Confirmation bias (100% of sampled texts) was represented by ignoring or dismissing information that would contradict the creationist hypothesis. Scientifically irrelevant or flawed information was re-interpreted as relevant for the falsification of evolution (75–90% of sampled texts). Evolutionary theory was associated to moral issues by demonizing scientists and linking evolutionary theory to atrocities (63–93% of sampled texts). Pro-evolutionary rebuttals of creationist claims also contained testimonials (93% of sampled texts) and referred to moral implications (80% of sampled texts) but displayed lower prevalences of stereotypical thinking (47% of sampled texts), confirmation bias (27% of sampled texts) and pseudodiagnostics (7% of sampled texts). The aspects of experiential thinking could also be interpreted as argumentative fallacies. Testimonials lead, for instance, to ad hominem and appeals to authorities. Confirmation bias and simplification of data give rise to hasty generalizations and false dilemmas. Moral issues lead to guilt by association and appeals to consequences. Experiential thinking and fallacies can contribute to false beliefs and the persistence of the claims. We propose that science educators would benefit from the systematic analysis of experiential thinking patterns and fallacies in creationist texts and pro-evolutionary rebuttals in order to concentrate on scientific misconceptions instead of the scientifically irrelevant aspects of the creationist

  10. Textrous!: Extracting Semantic Textual Meaning from Gene Sets

    PubMed Central

    Daimon, Caitlin M.; Siddiqui, Sana; Luttrell, Louis M.; Maudsley, Stuart

    2013-01-01

    The un-biased and reproducible interpretation of high-content gene sets from large-scale genomic experiments is crucial to the understanding of biological themes, validation of experimental data, and the eventual development of plans for future experimentation. To derive biomedically-relevant information from simple gene lists, a mathematical association to scientific language and meaningful words or sentences is crucial. Unfortunately, existing software for deriving meaningful and easily-appreciable scientific textual ‘tokens’ from large gene sets either rely on controlled vocabularies (Medical Subject Headings, Gene Ontology, BioCarta) or employ Boolean text searching and co-occurrence models that are incapable of detecting indirect links in the literature. As an improvement to existing web-based informatic tools, we have developed Textrous!, a web-based framework for the extraction of biomedical semantic meaning from a given input gene set of arbitrary length. Textrous! employs natural language processing techniques, including latent semantic indexing (LSI), sentence splitting, word tokenization, parts-of-speech tagging, and noun-phrase chunking, to mine MEDLINE abstracts, PubMed Central articles, articles from the Online Mendelian Inheritance in Man (OMIM), and Mammalian Phenotype annotation obtained from Jackson Laboratories. Textrous! has the ability to generate meaningful output data with even very small input datasets, using two different text extraction methodologies (collective and individual) for the selecting, ranking, clustering, and visualization of English words obtained from the user data. Textrous!, therefore, is able to facilitate the output of quantitatively significant and easily appreciable semantic words and phrases linked to both individual gene and batch genomic data. PMID:23646135

  11. Textrous!: extracting semantic textual meaning from gene sets.

    PubMed

    Chen, Hongyu; Martin, Bronwen; Daimon, Caitlin M; Siddiqui, Sana; Luttrell, Louis M; Maudsley, Stuart

    2013-01-01

    The un-biased and reproducible interpretation of high-content gene sets from large-scale genomic experiments is crucial to the understanding of biological themes, validation of experimental data, and the eventual development of plans for future experimentation. To derive biomedically-relevant information from simple gene lists, a mathematical association to scientific language and meaningful words or sentences is crucial. Unfortunately, existing software for deriving meaningful and easily-appreciable scientific textual 'tokens' from large gene sets either rely on controlled vocabularies (Medical Subject Headings, Gene Ontology, BioCarta) or employ Boolean text searching and co-occurrence models that are incapable of detecting indirect links in the literature. As an improvement to existing web-based informatic tools, we have developed Textrous!, a web-based framework for the extraction of biomedical semantic meaning from a given input gene set of arbitrary length. Textrous! employs natural language processing techniques, including latent semantic indexing (LSI), sentence splitting, word tokenization, parts-of-speech tagging, and noun-phrase chunking, to mine MEDLINE abstracts, PubMed Central articles, articles from the Online Mendelian Inheritance in Man (OMIM), and Mammalian Phenotype annotation obtained from Jackson Laboratories. Textrous! has the ability to generate meaningful output data with even very small input datasets, using two different text extraction methodologies (collective and individual) for the selecting, ranking, clustering, and visualization of English words obtained from the user data. Textrous!, therefore, is able to facilitate the output of quantitatively significant and easily appreciable semantic words and phrases linked to both individual gene and batch genomic data. PMID:23646135

  12. Experiential thinking in creationism--a textual analysis.

    PubMed

    Nieminen, Petteri; Ryökäs, Esko; Mustonen, Anne-Mari

    2015-01-01

    Creationism is a religiously motivated worldview in denial of biological evolution that has been very resistant to change. We performed a textual analysis by examining creationist and pro-evolutionary texts for aspects of "experiential thinking", a cognitive process different from scientific thought. We observed characteristics of experiential thinking as follows: testimonials (present in 100% of sampled creationist texts), such as quotations, were a major form of proof. Confirmation bias (100% of sampled texts) was represented by ignoring or dismissing information that would contradict the creationist hypothesis. Scientifically irrelevant or flawed information was re-interpreted as relevant for the falsification of evolution (75-90% of sampled texts). Evolutionary theory was associated to moral issues by demonizing scientists and linking evolutionary theory to atrocities (63-93% of sampled texts). Pro-evolutionary rebuttals of creationist claims also contained testimonials (93% of sampled texts) and referred to moral implications (80% of sampled texts) but displayed lower prevalences of stereotypical thinking (47% of sampled texts), confirmation bias (27% of sampled texts) and pseudodiagnostics (7% of sampled texts). The aspects of experiential thinking could also be interpreted as argumentative fallacies. Testimonials lead, for instance, to ad hominem and appeals to authorities. Confirmation bias and simplification of data give rise to hasty generalizations and false dilemmas. Moral issues lead to guilt by association and appeals to consequences. Experiential thinking and fallacies can contribute to false beliefs and the persistence of the claims. We propose that science educators would benefit from the systematic analysis of experiential thinking patterns and fallacies in creationist texts and pro-evolutionary rebuttals in order to concentrate on scientific misconceptions instead of the scientifically irrelevant aspects of the creationist-evolutionist debate

  13. A Dynamic Ensemble Framework for Mining Textual Streams with Class Imbalance

    PubMed Central

    Song, Ge

    2014-01-01

    Textual stream classification has become a realistic and challenging issue since large-scale, high-dimensional, and non-stationary streams with class imbalance have been widely used in various real-life applications. According to the characters of textual streams, it is technically difficult to deal with the classification of textual stream, especially in imbalanced environment. In this paper, we propose a new ensemble framework, clustering forest, for learning from the textual imbalanced stream with concept drift (CFIM). The CFIM is based on ensemble learning by integrating a set of clustering trees (CTs). An adaptive selection method, which flexibly chooses the useful CTs by the property of the stream, is presented in CFIM. In particular, to deal with the problem of class imbalance, we collect and reuse both rare-class instances and misclassified instances from the historical chunks. Compared to most existing approaches, it is worth pointing out that our approach assumes that both majority class and rareclass may suffer from concept drift. Thus the distribution of resampled instances is similar to the current concept. The effectiveness of CFIM is examined in five real-world textual streams under an imbalanced nonstationary environment. Experimental results demonstrate that CFIM achieves better performance than four state-of-the-art ensemble models. PMID:24982961

  14. Automating generation of textual class definitions from OWL to English

    PubMed Central

    2011-01-01

    by our survey and, as a result, the developers of EFO are sufficiently satisfied with the output that the generated definitions have been incorporated into EFO. Whilst not a substitute for hand-written textual definitions, our generated definitions are a useful starting point. Availability An on-line version of the NLG text definition tool can be found at http://swat.open.ac.uk/tools/. The questionaire and sample generated text definitions may be found at http://mcs.open.ac.uk/nlg/SWAT/bio-ontologies.html. PMID:21624160

  15. Tipos de cáncer

    Cancer.gov

    Lista alfabética de todos los tipos de cáncer con enlaces a enfermedades específicas e información general sobre tratamiento, cuidados de apoyo, exámenes de detección, prevención, estudios clínicos y otros temas.

  16. Instantánea del melanoma

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el melanoma; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  17. Instantánea del linfoma

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el linfoma; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  18. Instantánea del mieloma

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el mieloma; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  19. Instantánea del sarcoma

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el sarcoma; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  20. Automatic Authorship Detection Using Textual Patterns Extracted from Integrated Syntactic Graphs.

    PubMed

    Gómez-Adorno, Helena; Sidorov, Grigori; Pinto, David; Vilariño, Darnes; Gelbukh, Alexander

    2016-01-01

    We apply the integrated syntactic graph feature extraction methodology to the task of automatic authorship detection. This graph-based representation allows integrating different levels of language description into a single structure. We extract textual patterns based on features obtained from shortest path walks over integrated syntactic graphs and apply them to determine the authors of documents. On average, our method outperforms the state of the art approaches and gives consistently high results across different corpora, unlike existing methods. Our results show that our textual patterns are useful for the task of authorship attribution. PMID:27589740

  1. Effects of Textual and Animated Orienting Activities and Practice on Learning from Computer-Based Instruction.

    ERIC Educational Resources Information Center

    Rieber, Lloyd P.; Hannafin, Michael J.

    1988-01-01

    Describes study designed to examine the effects of textual and/or computer animated orienting strategies and practice on rule-using and problem-solving skills of elementary school students using computer-assisted instruction. Four different versions of a lesson based on Isaac Newton's Law of Motion are described, and results are analyzed. (28…

  2. Textual Enhancements and Comprehension with Adult Readers of English in China

    ERIC Educational Resources Information Center

    Brantmeier, Cindy; Callender, Aimee; Yu, Xiucheng; McDaniel, Mark

    2012-01-01

    The present study utilizes texts from social psychology to examine the effects of textual enhancements on reading comprehension with 185 native adult Chinese speakers learning English in China. Participants read two different vignettes, either with or without an adjunct. Each adjunct consisted of a "what" question along with instructions to either…

  3. Tonal Interface to MacroMolecules (TIMMol): A Textual and Tonal Tool for Molecular Visualization

    ERIC Educational Resources Information Center

    Cordes, Timothy J.; Carlson, C. Britt; Forest, Katrina T.

    2008-01-01

    We developed the three-dimensional visualization software, Tonal Interface to MacroMolecules or TIMMol, for studying atomic coordinates of protein structures. Key features include audio tones indicating x, y, z location, identification of the cursor location in one-dimensional and three-dimensional space, textual output that can be easily linked…

  4. SEPARATE.BAS: A Microcomputer Program to Assist in the Textual Analysis of Qualitative Data.

    ERIC Educational Resources Information Center

    Winograd, Edward B.; Winograd, Gaynell Rothermel

    1987-01-01

    Presents the computer program SEPARATE.BAS. and discusses how the use of microcomputer technology for processing textual data offers increased capabilities for the qualitative researcher in speech communication. Discusses how SEPARATE.BAS. assists in the research task of dividing transcripts of interviews or discussions into separate text files…

  5. Teach for America's Long Arc: A Critical Race Theory Textual Analysis of Wendy Kopp's Works

    ERIC Educational Resources Information Center

    Barnes, Michael C.; Germain, Emily K.; Valenzuela, Angela

    2016-01-01

    We read and analyzed 165,000 words and uncover a series of counter-stories buried within a textual corpus, authored by Teach For America (TFA) founder Wendy Kopp (Kopp, 1989, 2001; Kopp & Farr, 2011), that offers insight into the forms of racism endemic to Teach For America. All three counter-stories align with a critical race theory (CRT)…

  6. Anatomy of a Masterpiece: A Close Textual Analysis of Abraham Lincoln's Second Inaugural Address.

    ERIC Educational Resources Information Center

    Slagell, Amy R.

    1991-01-01

    States that Abraham Lincoln's second inaugural address is a recognized rhetorical masterpiece. Accounts for this recognition by examining the text microscopically. Uses the method of close textual analysis that explores the inner workings of the text to discover the complexity of Lincoln's masterwork. (PRA)

  7. Establishing Textual Authority and Separating Voices: A New Approach to Teaching Referencing

    ERIC Educational Resources Information Center

    Mott-Smith, Jennifer A.

    2011-01-01

    In this article the author discusses a new approach to teaching referencing based on establishing textual authority and separating writers' voices. She first presents a short discussion of key theoretical ideas that inform the approach, and then she describes five lessons, four of which are integrated into the course theme of "homelessness."…

  8. Students' Proficiency and Textual Computer Gloss Use in Facilitating Vocabulary Knowledge

    ERIC Educational Resources Information Center

    Yusuf, Mohamad A.; Sim, Tam S.; Su'ad A.

    2014-01-01

    Learning vocabulary forms a major part for any language learner. Apart from direct teaching of vocabulary, language teachers are always searching for ways to increase their students' vocabulary to enable them to use the language more effectively. Therefore, this study sets out to investigate whether the use of computer textual glosses can aid…

  9. The Textualization of Problem Handling: Lean Discourses Meet Professional Competence in Eldercare and the Manufacturing Industry

    ERIC Educational Resources Information Center

    Karlsson, Anna-Malin; Nikolaidou, Zoe

    2016-01-01

    This article reports on research addressing the role of incident reporting at the workplace as a textual representation of lean management techniques. It draws on text and discourse analysis as well as on ethnographic data, including interviews, recorded interaction, and observations, from two projects on workplace literacy in Sweden: a study in…

  10. Content Evaluation of Textual CD-ROM and Web Databases. Database Searching Series.

    ERIC Educational Resources Information Center

    Jacso, Peter

    This book provides guidelines for evaluating a variety of database types, including abstracting and indexing, directory, full-text, and page-image databases available in online and/or CD-ROM formats. The book discusses the purpose and techniques of comparing and evaluating the most important characteristics of textual databases, such as their…

  11. The Effects of Textual Prompting and Reading Fluency on the Acquisition of Intraverbals

    ERIC Educational Resources Information Center

    Emmick, Jill R.; Cihon, Traci M.; Eshleman, John W.

    2010-01-01

    The study examined the effects of textual prompt fading on the acquisition of intraverbals in 3 individuals with developmental disabilities. An alternating treatments design was used to assess the two independent variables. The first independent variable was transfer of stimulus control without component skill fluency. The second independent…

  12. Rereading Dis/Ability in Adolescent Literature: Textual Invitation & Repertoires in Reader Response

    ERIC Educational Resources Information Center

    Walker, Valerie Struthers

    2009-01-01

    This dissertation draws on textual reader response theory and humanities-based Disability Studies theories to explores the ways in which preservice teachers participating in a course called "Issues of Diversity in Children's and Adolescent Literature" and their instructor, who is also the researcher, made sense of representations of disability in…

  13. The Effects of Visual and Textual Annotations on Spanish Listening Comprehension, Vocabulary Acquisition and Cognitive Load

    ERIC Educational Resources Information Center

    Cottam, Michael Evan

    2010-01-01

    The purpose of this experimental study was to investigate the effects of textual and visual annotations on Spanish listening comprehension and vocabulary acquisition in the context of an online multimedia listening activity. 95 students who were enrolled in different sections of first year Spanish classes at a community college and a large…

  14. Establishing Derived Textual Control in Activity Schedules with Children with Autism

    ERIC Educational Resources Information Center

    Miguel, Caio F.; Yang, Heejean G.; Finn, Heather E.; Ahearn, William H.

    2009-01-01

    Activity schedules are often used to facilitate task engagement and transition for children with autism. This study evaluated whether conditional discrimination training would serve to transfer the control from activity-schedule pictures to printed words (i.e., derived textual control). Two preschoolers with autism were taught to select pictures…

  15. The Investigation of Power in Written Texts through the Use of Multiple Textual Analytic Frames

    ERIC Educational Resources Information Center

    Wickens, Corrine M.

    2011-01-01

    Although often used as secondary sources, written texts are powerful sources of data for qualitative researchers to explore power networks and broad ideological perspectives. As such, I present in this paper an analytic process that draws upon multiple analytic frameworks--constant comparative analysis, discursive textual analysis, and traditional…

  16. Game Design as Textual Poaching: Media Literacy, Creativity and Game-Making

    ERIC Educational Resources Information Center

    Pelletier, Caroline; Burn, Andrew; Buckingham, David

    2010-01-01

    This article addresses practices of textual appropriation in computer games made by young people. By focusing on how young people's production work makes reference to popular media texts, it examines the basis on which such work claims to be legible as a game text: how it claims to be literate in the context of an after-school game-making club.…

  17. The Illusion of Inclusion: A Critical Race Theory Textual Analysis of Race and Standards

    ERIC Educational Resources Information Center

    Heilig, Julian Vasquez; Brown, Keffrelyn D.; Brown, Anthony L.

    2012-01-01

    In this article, Julian Vasquez Heilig, Keffrelyn Brown, and Anthony Brown offer findings from a close textual analysis of how the Texas social studies standards address race, racism, and communities of color. Using the lens of critical race theory, the authors uncover the sometimes subtle ways that the standards can appear to adequately address…

  18. Children's Use of Anaphora in Discourse: A Progression from Situational to Textual Reference.

    ERIC Educational Resources Information Center

    Dent, Cathy H.

    Children's use of proforms in spoken descriptions of real situations was studied and compared with that of adults to explore possible developmental progressions in the use of indexical reference. A discourse distinction between situational and textual reference was applied to data from 6-year-old and 10-year-old children and from adults. Subjects…

  19. Predicting Learning-Related Emotions from Students' Textual Classroom Feedback via Twitter

    ERIC Educational Resources Information Center

    Altrabsheh, Nabeela; Cocea, Mihaela; Fallahkhair, Sanaz

    2015-01-01

    Teachers/lecturers typically adapt their teaching to respond to students' emotions, e.g. provide more examples when they think the students are confused. While getting a feel of the students' emotions is easier in small settings, it is much more difficult in larger groups. In these larger settings textual feedback from students could provide…

  20. We Could Make a Book: The Textual Tradition of Navajo Language Literacy in 1940-1990.

    ERIC Educational Resources Information Center

    Lockard, Louise

    1998-01-01

    The textual tradition of Navajo language literacy is illustrated with the story of the production of the first Navajo language readers by Ann Nolan Clark, an effort based in Navajo classrooms and communities in the 1930s. Origins of the project, influence of linguists on its evolution, classroom implications of having the readers, and publications…

  1. Students' Mind Wandering in Macroscopic and Submicroscopic Textual Narrations and Its Relationship with Their Reading Comprehension

    ERIC Educational Resources Information Center

    Al-Balushi, Sulaiman M.; Al-Harthy, Ibrahim S.

    2015-01-01

    The aim of the current study was to investigate students' mind wandering while reading different types of textual narrations (macroscopic and submicroscopic) in chemistry. Another goal was to determine the relationship between mind wandering and students' reading comprehension. The participants were 65 female ninth grade students in Oman. Using a…

  2. Textual Enhancement of Two L2 Arabic Forms: A Classroom-Based Study

    ERIC Educational Resources Information Center

    Park, Eun Sung; Nassif, Lama

    2014-01-01

    Research on textual enhancement (TE) has given rise to several factors that may play a role in generating learners' noticing of target forms, one of which pertains to the nature of the target form(s). In particular, results have suggested that learners are more likely to notice more meaning-bearing forms than less meaning-bearing forms.…

  3. Complicating Predictability: Textuality, Intertextuality, and Intercontextuality in Beginning Reading and Writing.

    ERIC Educational Resources Information Center

    Meyer, Richard; Martens, Prisca; Flurkey, Alan; Udell, Risa

    1998-01-01

    Investigates the nature and role of predictable texts for beginning readers and writers in first grade. Examines ways three children used texts to support their early-literacy development. Finds diverse and complex activities, as children made links within a text (textuality), between texts (intertextuality), and between texts and contexts…

  4. Habits of Mind: Historical Configurations of Textual Ownership in Peer Writing Groups.

    ERIC Educational Resources Information Center

    Spigelman, Candace

    1998-01-01

    Argues that students' attitudes about authorship and intellectual property rights are evidence of cultural habits of mind. Overviews perceptions of literary products as public and/or private property. Explores conflicts in legal notions of textual ownership relating to copyrights and the idea/expression dichotomy in American Constitutional law.…

  5. Discourses of Plagiarism: Moralist, Proceduralist, Developmental and Inter-Textual Approaches

    ERIC Educational Resources Information Center

    Kaposi, David; Dell, Pippa

    2012-01-01

    This paper reconstructs prevalent academic discourses of student plagiarism: moralism, proceduralism, development, and writing/inter-textuality. It approaches the discourses from three aspects: intention, interpretation and the nature of the academic community. It argues that the assumptions of the moralistic approach regarding suspect intention,…

  6. A New Framework for Textual Information Mining over Parse Trees. CRESST Report 805

    ERIC Educational Resources Information Center

    Mousavi, Hamid; Kerr, Deirdre; Iseli, Markus R.

    2011-01-01

    Textual information mining is a challenging problem that has resulted in the creation of many different rule-based linguistic query languages. However, these languages generally are not optimized for the purpose of text mining. In other words, they usually consider queries as individuals and only return raw results for each query. Moreover they…

  7. Analyzing Student Performance and Attitudes toward Textual versus Iconic Programming Languages

    ERIC Educational Resources Information Center

    Lin, Janet Mei-Chuen; Yang, Mei-Ching

    2009-01-01

    In this study half of 52 sixth graders learned to program in MSWLogo and the other half in Drape. An analysis of students' test scores revealed that Drape (an iconic language) seemed to have a steeper learning curve than MSWLogo (a textual language). However, as students gradually became more familiar with either language, the difference in…

  8. Effects of Textual Enhancement and Input Enrichment on L2 Development

    ERIC Educational Resources Information Center

    Rassaei, Ehsan

    2015-01-01

    Research on second language (L2) acquisition has recently sought to include formal instruction into second and foreign language classrooms in a more unobtrusive and implicit manner. Textual enhancement and input enrichment are two techniques which are aimed at drawing learners' attention to specific linguistic features in input and at the same…

  9. The Aesthetics of Textual Production: Reading and Writing with Umberto Eco

    ERIC Educational Resources Information Center

    Trifonas, Peter Pericles

    2007-01-01

    In "The Name of the Rose," Umberto Eco essentially presents an educative vision of some basic semiotic principles that infuse the textual form of a popular fictional genre--the detective story. In effect, it characterizes the postmodernization of the traditional "whodunnit" moving the genre from the realm of "the real" or the plausible into the…

  10. Arguing in L2: Discourse Structure and Textual Metadiscourse in Philippine Newspaper Editorials

    ERIC Educational Resources Information Center

    Tarrayo, Veronico N.; Duque, Marie Claire T.

    2011-01-01

    This study described the discourse structure and textual metadiscourse in newspaper editorials in the Philippines where English is used as a second language or L2. Specifically, it sought answers to the following questions: (1) What discourse features characterize the structure of the following parts of Philippine newspaper editorials--orientation…

  11. Information Structure and Practice as Facilitators of Deaf Users' Navigation in Textual Websites

    ERIC Educational Resources Information Center

    Fajardo, I.; Canas, J. J.; Salmeron, L.; Abascal, J.

    2009-01-01

    Deaf users might find it difficult to navigate through websites with textual content which, for many of them, constitutes the written representation of a non-native oral language. With the aim of testing how the information structure could compensate for this difficulty, 27 prelingual deaf users of sign language were asked to search a set of…

  12. The Effect of Textual Metafunction on the Iranian EFL Learners' Writing Performance

    ERIC Educational Resources Information Center

    Paziraie, Mandana Eftekhar

    2013-01-01

    This study is devoted to the effect of "textual metafunction" on the levels of coherence and cohesion in the Iranian EFL learners' English writing performance. Sixty Iranian intermediate EFL learners who were adult females participated in this study were randomly divided into two groups; experimental, and control. They were given a…

  13. Written Textual Production and Consumption (WTPC) in Vernacular and English-Medium Settings in Gujarat, India.

    ERIC Educational Resources Information Center

    Ramanathan, Vaidehi

    2003-01-01

    Sketches key facets in the larger socioeducational machinery that shapes the written textual production and consumption (WTPC) of English-medium (EM) and "vernacular-medium" (VM) students in Gujarat, India. Lays out ways in which articulator macro-structures align together to produce and shape conditions that privilege the WTPC of EM students over…

  14. Framing Student Evaluations of University Learning and Teaching: Discursive Strategies and Textual Outcomes

    ERIC Educational Resources Information Center

    Ryan, Mary

    2015-01-01

    Evaluation in higher education is an evolving social practice; that is, it involves what people, institutions and broader systems do and say, how they do and say it, what they value, the effects of these practices and values, and how meanings are ascribed. The textual products (verbal, written, visual and gestural) that inform and are produced by,…

  15. Use of a Modified Chaining Procedure with Textual Prompts to Establish Intraverbal Storytelling

    ERIC Educational Resources Information Center

    Valentino, Amber L.; Conine, Daniel E.; Delfs, Caitlin H.; Furlow, Christopher M.

    2015-01-01

    Echoic, tact, and textual transfer procedures have been proven successful in establishing simple intraverbals (Braam and Poling "Applied Research in Mental Retardation," 4, 279-302, 1983; Luciano "Applied Research in Mental Retardation," 102, 346-357, 1986; Watkins et al. "The Analysis of Verbal Behavior," 7, 69-81,…

  16. Perceptions and Beliefs about Textual Appropriation and Source Use in Second Language Writing

    ERIC Educational Resources Information Center

    Polio, Charlene; Shi, Ling

    2012-01-01

    Perceptions and judgments on plagiarism or acceptable use of source texts are contingent on one's interpretations and experiences in reading and writing academic texts in a specific disciplinary context. The lack of consensus on what is acceptable textual appropriation in student writing has led to the scholarship on perceptions of textual…

  17. Conditioned Observation of Books and Accelerated Acquisition of Textual Responding by Preschool Children

    ERIC Educational Resources Information Center

    Tsai, Hshin-hui; Greer, R. Douglas

    2006-01-01

    We report an experiment investigating the effects of conditioning books as reinforcers for observing responses on the learning of textual responses by pre-school children. The independent variable was the acquisition of conditioned reinforcement of observing responses and choice of book stimuli in free play settings where children could choose to…

  18. Textual alchemy: the transformation of pseudo-Albertus Magnus's Semita recta into the Mirror of Lights.

    PubMed

    Grund, Peter

    2009-11-01

    This article explores the strategies of and the reasons behind the reworking of pseudo-Albertus Magnus's Semita recta into the Mirror of Lights. I argue that the redactor sought to provide a more comprehensive defence of the legitimacy of alchemy than found in the Semita recta. In the process of doing so, he reshaped the original text so as to present three units that addressed different parts of the alchemical opus: first, theory and justification of alchemy; second, basic information on substances and procedures; and, third, practice. The redactor employed sophisticated textual tools identical to those seen in scholastic texts. These strategies, I argue, constitute part of the redactor's attempt to bring authority and credibility to his project and to alchemy in general. Certainly, much more attention needs to be paid to these experiments of textual alchemy in order to understand the practice of alchemy in the late medieval period. PMID:20506702

  19. Linnaeus' restless system: translation as textual engineering in eighteenth-century botany.

    PubMed

    Dietz, Bettina

    2016-04-01

    In this essay, translations of Linnaeus' Systema naturae into various European languages will be placed into the context of successively expanded editions of Linnaeus' writings. The ambition and intention of most translators was not only to make the Systema naturae accessible for practical botanical use by a wider readership, but also to supplement and correct it, and thus to shape it. By recruiting more users, translations made a significant contribution to keeping the Systema up to date and thus maintaining its practical value for decades. The need to incorporate countless additions and corrections into an existing text, to document their provenance, to identify inconsistencies, and to refer to relevant observations, descriptions, and illustrations in the botanical literature all helped to develop and refine techniques of textual montage. This form of textual engineering, becoming increasingly complex with each translation cycle, shaped the external appearance of new editions of the Systema, and reflected the modular architecture of a botanical system designed for expansion. PMID:27391666

  20. Flight Deck Data Link Displays: An Evaluation of Textual and Graphical Implementations

    NASA Technical Reports Server (NTRS)

    McGann, Alison; Lozito, Sandy; Corker, Kevin; Ashford, Rose (Technical Monitor)

    2001-01-01

    In Experiment 1, 16 pilots participated in a part-task simulation study that evaluated pilot data link communication for short and long message types and for two textual formats. No differences were found between the two textual formats when evaluating data link transaction times and pilot performance on a secondary task. Pilots initiated flight changes more quickly with the T-Scan format, where location of clearance information roughly corresponded to the cockpit instrument layout. Longer messages were less problematic than two short messages sent in close succession as pilots required more verbal clarification for closely spaced messages. 24 pilots participated in a second experiment that evaluated pilot communication performance for textual data link, two implementations of graphical data link, and a combined graphical and textual information modality. The two modalities incorporating text resulted in significantly faster transaction times and better performance on the secondary task than the two graphical-only implementations. The interval between messages was also more systematically varied in Experiment 2, and a short interval between messages significantly increased the access time for the second message. This delay in access was long enough to increase significantly the total transaction time of the second message, and this effect was exaggerated for the graphical-only implementations. Time to view the message before acknowledgement and time to initiate flight changes were not affected by the interval manipulation, This suggests that pilots adopt a sequential message handling strategy, and presenting messages closely in succession may present operational problems in a data link Air Traffic Control (ATC) environment. The results of this study also indicate that the perceived importance of message content is currently a crucial element in pilot data link communication.

  1. Knowledge Discovery in Textual Databases: A Concept-Association Mining Approach

    NASA Astrophysics Data System (ADS)

    Mete, Mutlu; Yuruk, Nurcan; Xu, Xiaowei; Berleant, Daniel

    The number of scientific publications is exploding as online digital libraries and the World Wide Web grow. MEDLINE, the premier bibliographic database of the National Library of Medicine (NLM), contains about 18 million records from more than 7,300 different publications dating from 1965; it is growing by about 400,000 citations each year. The explosive growth of information in textual documents creates great need for techniques for knowledge discovery from text collections.

  2. Knowledge Discovery in Textual Databases: A Concept-Association Mining Approach

    NASA Astrophysics Data System (ADS)

    Mete, Mutlu; Yuruk, Nurcan; Xu, Xiaowei; Berleant, Daniel

    The number of scientific publications is exploding as online digital libraries and the World Wide Web grow. MEDLINE, the premier bibliographic database of the National Library of Medicine (NLM) , contains about 18 million records from more than 7,300 different publications dating from 1965; it is growing by about 400,000 citations each year. The explosive growth of information in textual documents creates great need for techniques for knowledge discovery from text collections.

  3. Insights triggered by textual micro-counseling dialogues of restructuring orientation in experts and students.

    PubMed

    Yu, Fei; Zhang, Wencai; Zhang, Zhijie; Zhang, Jianxin; Luo, Jing

    2016-03-01

    Insight is a salient psychotherapeutic progress but has rarely been measured in a controlled experimental setting. This study aimed to assess whether textual micro-counseling dialogue could validly evoke insight and to explore the characteristics of insight. The guessing riddle of cognitive psychology was used as a reference of the experimental paradigm. Specifically, textual micro-counseling dialogues applying cognitive restructuring techniques were presented. The participant first read a description of a psychological distress ("problem") and then an explanation ("solution"). Zero-, low-, and high-restructuring solutions were randomly matched to the problems and it was expected that they would trigger different levels of insight experiences. Experts and students evaluated the adaptability and emotional valence of problems, and the insightfulness, novelty, adaptability, and emotional valence of solutions. For both experts and students, different intensities of insightfulness were produced across high-, low- and zero-restructuring solutions. Novelty significantly discriminated the high-restructuring solutions from the other two solution types. Adaptability and emotional valence could discriminate the high- and low-restructuring solutions types from the zero-restructuring solution. Insightfulness had high correlations with novelty and adaptability. These results indicated that textual micro-counseling dialogues with a high-restructuring solution could validly produce the greatest insightfulness and the features of high-restructuring solutions may have reference meaning for improving psychotherapeutic effect. PMID:26377623

  4. Improved medical image modality classification using a combination of visual and textual features.

    PubMed

    Dimitrovski, Ivica; Kocev, Dragi; Kitanovski, Ivan; Loskovska, Suzana; Džeroski, Sašo

    2015-01-01

    In this paper, we present the approach that we applied to the medical modality classification tasks at the ImageCLEF evaluation forum. More specifically, we used the modality classification databases from the ImageCLEF competitions in 2011, 2012 and 2013, described by four visual and one textual types of features, and combinations thereof. We used local binary patterns, color and edge directivity descriptors, fuzzy color and texture histogram and scale-invariant feature transform (and its variant opponentSIFT) as visual features and the standard bag-of-words textual representation coupled with TF-IDF weighting. The results from the extensive experimental evaluation identify the SIFT and opponentSIFT features as the best performing features for modality classification. Next, the low-level fusion of the visual features improves the predictive performance of the classifiers. This is because the different features are able to capture different aspects of an image, their combination offering a more complete representation of the visual content in an image. Moreover, adding textual features further increases the predictive performance. Finally, the results obtained with our approach are the best results reported on these databases so far. PMID:24997992

  5. Using Semantic Web technology to support icd-11 textual definitions authoring.

    PubMed

    Jiang, Guoqian; Solbrig, Harold R; Chute, Christopher G

    2013-01-01

    The beta phase of the 11th revision of International Classification of Diseases (ICD-11) intends to accept public input through a distributed model of authoring. One of the core use cases is to create textual definitions for the ICD categories. The objective of the present study is to design, develop, and evaluate approaches to support ICD-11 textual definitions authoring using Semantic Web technology. We investigated a number of heterogeneous resources related to the definitions of diseases, including the linked open data (LOD) from DBpedia, the textual definitions from the Unified Medical Language System (UMLS) and the formal definitions of the Systematized Nomenclature of Medicine-Clinical Terms (SNOMED CT). We integrated them in a Semantic Web framework (i.e., the Linked Data in a Resource Description Framework [RDF] triple store), which is being proposed as a backend in a prototype platform for collaborative authoring of ICD-11 beta. We performed a preliminary evaluation on the usefulness of our approaches and discussed the potential challenges from both technical and clinical perspectives. PMID:23601451

  6. Using Semantic Web technology to support icd-11 textual definitions authoring

    PubMed Central

    2013-01-01

    The beta phase of the 11th revision of International Classification of Diseases (ICD-11) intends to accept public input through a distributed model of authoring. One of the core use cases is to create textual definitions for the ICD categories. The objective of the present study is to design, develop, and evaluate approaches to support ICD-11 textual definitions authoring using Semantic Web technology. We investigated a number of heterogeneous resources related to the definitions of diseases, including the linked open data (LOD) from DBpedia, the textual definitions from the Unified Medical Language System (UMLS) and the formal definitions of the Systematized Nomenclature of Medicine—Clinical Terms (SNOMED CT). We integrated them in a Semantic Web framework (i.e., the Linked Data in a Resource Description Framework [RDF] triple store), which is being proposed as a backend in a prototype platform for collaborative authoring of ICD-11 beta. We performed a preliminary evaluation on the usefulness of our approaches and discussed the potential challenges from both technical and clinical perspectives. PMID:23601451

  7. Comparing the quality of accessing medical literature using content-based visual and textual information retrieval

    NASA Astrophysics Data System (ADS)

    Müller, Henning; Kalpathy-Cramer, Jayashree; Kahn, Charles E., Jr.; Hersh, William

    2009-02-01

    Content-based visual information (or image) retrieval (CBIR) has been an extremely active research domain within medical imaging over the past ten years, with the goal of improving the management of visual medical information. Many technical solutions have been proposed, and application scenarios for image retrieval as well as image classification have been set up. However, in contrast to medical information retrieval using textual methods, visual retrieval has only rarely been applied in clinical practice. This is despite the large amount and variety of visual information produced in hospitals every day. This information overload imposes a significant burden upon clinicians, and CBIR technologies have the potential to help the situation. However, in order for CBIR to become an accepted clinical tool, it must demonstrate a higher level of technical maturity than it has to date. Since 2004, the ImageCLEF benchmark has included a task for the comparison of visual information retrieval algorithms for medical applications. In 2005, a task for medical image classification was introduced and both tasks have been run successfully for the past four years. These benchmarks allow an annual comparison of visual retrieval techniques based on the same data sets and the same query tasks, enabling the meaningful comparison of various retrieval techniques. The datasets used from 2004-2007 contained images and annotations from medical teaching files. In 2008, however, the dataset used was made up of 67,000 images (along with their associated figure captions and the full text of their corresponding articles) from two Radiological Society of North America (RSNA) scientific journals. This article describes the results of the medical image retrieval task of the ImageCLEF 2008 evaluation campaign. We compare the retrieval results of both visual and textual information retrieval systems from 15 research groups on the aforementioned data set. The results show clearly that, currently

  8. Instantánea del sarcoma de Kaposi

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el sarcoma de Kaposi; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  9. Instantánea del cáncer colorrectal

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer colorrectal; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  10. Analyzing Cultural Usability of Mobile Keypad and Displays for Textual Communication in Internationalization and Localization Perspectives

    NASA Astrophysics Data System (ADS)

    Orngreen, Rikke; Katre, Dinesh; Sandeep, Mulagapati

    The aim of this paper is to identify the cultural usability aspects that need to be considered while internationalizing or localizing the interaction design of mobile keypads and displays for textual communication. The analysis is based primarily on heuristics tests, where: Hindi, Arabic and Danish mobile phones are evaluated based on assumptions of user needs, and in comparison to English. We have also referred the existing research on Chinese mobile phones to further complement our work. The study provides an insight into the much needed local-language centred approach in contrast with the current English centred approach of existing mobile keypad designs and display of text.

  11. Integrating Ontological Knowledge and Textual Evidence in Estimating Gene and Gene Product Similarity

    SciTech Connect

    Sanfilippo, Antonio P.; Posse, Christian; Gopalan, Banu; Tratz, Stephen C.; Gregory, Michelle L.

    2006-06-08

    With the rising influence of the Gene On-tology, new approaches have emerged where the similarity between genes or gene products is obtained by comparing Gene Ontology code annotations associ-ated with them. So far, these approaches have solely relied on the knowledge en-coded in the Gene Ontology and the gene annotations associated with the Gene On-tology database. The goal of this paper is to demonstrate that improvements to these approaches can be obtained by integrating textual evidence extracted from relevant biomedical literature.

  12. Deficits of cognitive restructuring in major depressive disorder: Measured by textual micro-counseling dialogues.

    PubMed

    Jiang, Nengzhi; Yu, Fei; Zhang, Wencai; Zhang, Jianxin

    2016-04-30

    Cognitive restructuring is an important strategy in cognitive behavioral therapy (CBT). The present study aimed to observe cognitive restructuring in major depressive disorder (MDD) patients using textual micro-counseling dialogue situations. A set of textual micro-counseling dialogues was used to trigger cognitive restructuring in 25 MDD patients and 27 healthy adults. The participants read descriptions ("problems") and explanations ("solutions") for psychologically distressing situations. High-, low-, and zero-restructuring solutions were randomly matched to the problems. The participants evaluated the adaptability and emotional valence of the problems and the insightfulness, adaptability, novelty, and emotional valence of the solutions. Insightfulness ratings for high-restructuring solutions were significantly higher relative to those of low-restructuring solutions in healthy adults, while adaptability ratings for low-restructuring solutions were significantly higher relative to those of high-restructuring solutions in MDD patients. Insightfulness ratings for the solutions were significantly predicted by novelty and adaptability in healthy adults and emotional valence in MDD patients. Lower insightfulness in high-restructuring solutions and higher adaptability in low-restructuring solutions in MDD patients may reflect deficits in cognitive control. PMID:27086227

  13. Content-based retrieval of historical Ottoman documents stored as textual images.

    PubMed

    Saykol, Ediz; Sinop, Ali Kemal; Güdükbay, Ugur; Ulusoy, Ozgür; Cetin, A Enis

    2004-03-01

    There is an accelerating demand to access the visual content of documents stored in historical and cultural archives. Availability of electronic imaging tools and effective image processing techniques makes it feasible to process the multimedia data in large databases. In this paper, a framework for content-based retrieval of historical documents in the Ottoman Empire archives is presented. The documents are stored as textual images, which are compressed by constructing a library of symbols occurring in a document, and the symbols in the original image are then replaced with pointers into the codebook to obtain a compressed representation of the image. The features in wavelet and spatial domain based on angular and distance span of shapes are used to extract the symbols. In order to make content-based retrieval in historical archives, a query is specified as a rectangular region in an input image and the same symbol-extraction process is applied to the query region. The queries are processed on the codebook of documents and the query images are identified in the resulting documents using the pointers in textual images. The querying process does not require decompression of images. The new content-based retrieval framework is also applicable to many other document archives using different scripts. PMID:15376924

  14. Viewing experiences of two-dimensional photos and textual content on autostereoscopic three-dimensional displays

    NASA Astrophysics Data System (ADS)

    Salmimaa, Marja; Järvenpää, Toni; Pölönen, Monika

    2012-01-01

    We examined the image quality, image clarity, and viewing comfort of 2-D images rendered on an autostereoscopic display. Opinions on daily use of the content was gathered. Two different stereo displays were used in the experiments--a lenticular lens stereo display employing fixed 3-D stereo and a display with a switchable lenticular lens structure. Images were rendered on the displays with three different rendering schemes. Photos of natural scenes, artificial content, and content containing textual elements were used as the test stimuli. When images with natural scenes or artificial content were categorized into clusters according to the amount of details, significant differences in image quality, image clarity, and viewing comfort scores were observed. When two of the schemes were compared using the images containing textual elements, a significant difference in the viewing comfort and a significant increase in perceived stereoscopic depth impression were found with one of the schemes. Furthermore, image quality and viewing comfort were better with the 2-D display mode than with the 3-D mode. The use of the 2-D text content in the 3-D display mode seemed to be acceptable in general, but for longer term and repeated use, improvements in text quality should be considered. The results indicate that an increase in detail levels may decrease the evaluated image quality, clarity, and viewing comfort. Moreover, for all experimental conditions, better image quality, increased image clarity, and a more comfortable viewing experience had a positive influence on decisions of daily use.

  15. Biomedical imaging modality classification using combined visual features and textual terms.

    PubMed

    Han, Xian-Hua; Chen, Yen-Wei

    2011-01-01

    We describe an approach for the automatic modality classification in medical image retrieval task of the 2010 CLEF cross-language image retrieval campaign (ImageCLEF). This paper is focused on the process of feature extraction from medical images and fuses the different extracted visual features and textual feature for modality classification. To extract visual features from the images, we used histogram descriptor of edge, gray, or color intensity and block-based variation as global features and SIFT histogram as local feature. For textual feature of image representation, the binary histogram of some predefined vocabulary words from image captions is used. Then, we combine the different features using normalized kernel functions for SVM classification. Furthermore, for some easy misclassified modality pairs such as CT and MR or PET and NM modalities, a local classifier is used for distinguishing samples in the pair modality to improve performance. The proposed strategy is evaluated with the provided modality dataset by ImageCLEF 2010. PMID:21912534

  16. [Textual research of Hou ke mi yao (Secret Key of Laryngology)].

    PubMed

    Zhang, Liang-Liang

    2013-05-01

    Hou ke mi yao (Secret Key of Laryngology) was one of the most popular books of throat department in the Qing Dynasty. Because of the inscription "Xiyuan Zheng of ancient She as the author, Xu Zuo-ting of Lequan revised and enlarged", this book was generally regarded as the important work of Xin'an Zheng's family of throat department. However, after the textual research, Hou ke mi yao, in fact, was edited on the basis of Zhang Zong-liang's Hou ke zhi zhang (Guide Book for Laryngology) of the Qing Dynasty: with the second volume, "method of processing" deleted, and Wu's "verse of 24 kinds of symptom of throat diseases" (his whole name unknown) and 12 pills added. Thus, the author of Hou ke mi yao was Zhang and Wu instead of Xiyuan Zheng, and the contents reflected the academic thought of Zhang Zong-liang and Wu. According to the record of General Catalogue of the Ancient Literature of Chinese Medicine in China, there were 14 editions of Hou ke mi yao available, however, only 12 editions are extant after the investigation. In addition, there are mistakes of its author, book title and editions included in the Textual Research on Chinese Medical Literature and General Catalogue of the Ancient Literature of Chinese Medicine in China which, therefore, should be corrected. PMID:24060030

  17. Accuracy of Judgments of Personality Based on Textual Information on Major Life Domains.

    PubMed

    Borkenau, Peter; Mosch, Alice; Tandler, Nancy; Wolf, Annegret

    2016-04-01

    We studied the accuracy of personality impressions relying on textual information on important life domains. Specifically, how is accuracy moderated by the trait being judged, information being provided, judgeability of target persons, and perceptiveness of judges? A sample of 208 students was recruited in groups of four mutual acquaintances who described themselves and each other on a measure of the Five-Factor Model of personality. Moreover, they wrote essays on their hobbies, friends, family, academic studies, and plans for the future and provided self-reports on possible predictors of expressive accuracy. The essays were delivered to 130 strangers who reported their impressions of the personality of the targets and provided self-reports on possible predictors of perceptive accuracy. Accuracy was measured by correlating these impressions with the descriptions of the targets by their acquaintances. The judges used the available information efficiently. Overall, impressions of Openness to Experience were most accurate, but accuracy depended on the information being provided. Several predictors of expressive and perceptive accuracy were identified using Biesanz's (2010) social accuracy model. The results advance our understanding of factors contributing to and moderating the accuracy of personality impressions based on textual information. PMID:25417640

  18. Textual and visual content-based anti-phishing: a Bayesian approach.

    PubMed

    Zhang, Haijun; Liu, Gang; Chow, Tommy W S; Liu, Wenyin

    2011-10-01

    A novel framework using a Bayesian approach for content-based phishing web page detection is presented. Our model takes into account textual and visual contents to measure the similarity between the protected web page and suspicious web pages. A text classifier, an image classifier, and an algorithm fusing the results from classifiers are introduced. An outstanding feature of this paper is the exploration of a Bayesian model to estimate the matching threshold. This is required in the classifier for determining the class of the web page and identifying whether the web page is phishing or not. In the text classifier, the naive Bayes rule is used to calculate the probability that a web page is phishing. In the image classifier, the earth mover's distance is employed to measure the visual similarity, and our Bayesian model is designed to determine the threshold. In the data fusion algorithm, the Bayes theory is used to synthesize the classification results from textual and visual content. The effectiveness of our proposed approach was examined in a large-scale dataset collected from real phishing cases. Experimental results demonstrated that the text classifier and the image classifier we designed deliver promising results, the fusion algorithm outperforms either of the individual classifiers, and our model can be adapted to different phishing cases. PMID:21824844

  19. The effects of question types in textual reading upon retention of biology concepts

    NASA Astrophysics Data System (ADS)

    Leonard, William H.; Lowery, Lawrence F.

    Do instructional questions to students enhance learning? If so, do certain types of questions cause greater learning outcomes than others? The area of instructional questions and questioning strategies has generated much research over the past two decades. A number of studies have found instructional questions to account for a large fraction of teaching time (Bellack et al., 1963; Schreiber, 1967; Moyer, 1967). Teacher use of oral questions in instruction, especially higher level cognitive questions, has consistently shown positive effects on student achievement (Redfield & Rousseau, 1981). Questions asked after oral prose presentations in psychology have been found to enhance recall of factual information (Sefkow & Meyers, 1980). Some large teacher training programs have specific instruction in questioning strategies (Lanier & Davis, 1972; Lowery, 1974). Questioning in textual reading has also been investigated, especially in the social sciences and languages, with respect to both the presence of questions in a text and the position and type of such questions. Although there are conflicting results, in general, questions placed within text materials have appeared to cause significantly higher performance than reading the materials without questions (Rothkopf & Bisbicos, 1967; Rothkopf & Bloom, 1970; Watts & Anderson, 1971; Quellmalz, 1972; Reynolds, Standiford, & Anderson, 1979; Corrozi, 1971). Questions placed after the reading have been found to be significantly more productive than prequestions, or questions placed immediately before the reading passages (Rothkopf & Bisbicos, 1967; Frase, Patrick, & Schumer, 1970; Watts & Anderson, 1971). In one study, placing questions before the associated information reduced paragraph reading time from the time required when questions followed the information passage (Morasky & Wilcox, 1970). Finally, higher level cognitive post- and prequestions (comprehensive and application) have consistently produced more learning than

  20. Instantánea de los cánceres de cerebro y del sistema nervioso central

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre los cánceres de cerebro y del sistema nervioso central; así como ejemplos de actividades del NCI y adelantos en la investigación de estos tipos de cáncer.

  1. The Generator of the Event Structure Lexicon (GESL): Automatic Annotation of Event Structure for Textual Inference Tasks

    ERIC Educational Resources Information Center

    Im, Seohyun

    2013-01-01

    This dissertation aims to develop the Generator of the Event Structure Lexicon (GESL) which is a tool to automate annotating the event structure of verbs in text to support textual inference tasks related to lexically entailed subevents. The output of the GESL is the Event Structure Lexicon (ESL), which is a lexicon of verbs in text which includes…

  2. Effects of Textual Enhancement and Topic Familiarity on Korean EFL Students' Reading Comprehension and Learning of Passive Form

    ERIC Educational Resources Information Center

    Lee, Sang-Ki

    2007-01-01

    This quasi-experimental study attempts to incorporate grammatical elements into meaning-focused reading classes by attracting learner attention to form with minimal interruption to meaning comprehension. Two hundred fifty-nine Korean English as a foreign language students underwent four different treatments--involving textual enhancement and topic…

  3. Pretext, Context, Subtext: Textual Power in the Writing of Langston Hughes, Richard Wright, and Martin Luther King, Jr.

    ERIC Educational Resources Information Center

    Bogumil, Mary L.; Molino, Michael R.

    1990-01-01

    Studies verbal pretexts, social subtexts, and interpretive contexts of works by Langston Hughes, Richard Wright, and Martin Luther King, Jr. Notes that cultural repression is propagated (and dispelled) in part through the power of language. Notes that these texts are relevant for teaching textual power in hopes of affecting social change. (RS)

  4. The Impact of Textual Input Enhancement and Explicit Rule Presentation on Iranian Elementary EFL Learners' Intake of Simple Past Tense

    ERIC Educational Resources Information Center

    Nahavandi, Naemeh; Mukundan, Jayakaran

    2013-01-01

    The present study investigated the impact of textual input enhancement and explicit rule presentation on 93 Iranian EFL learners' intake of simple past tense. Three intact general English classes in Tabriz Azad University were randomly assigned to: 1) a control group; 2) a TIE group; and 3) a TIE plus explicit rule presentation group. All…

  5. Integrating Language and Literature: Teaching Textual Analysis with Input and Output Activities and an Input-to-Output Approach

    ERIC Educational Resources Information Center

    Weber-Feve, Stacey

    2009-01-01

    The Modern Language Association report and "Profession" issue from summer 2007 (Geisler et al., 2007) are highly indicative of the increasingly debated concerns in the profession surrounding (1) the traditional division of foreign language curriculum between "language" and "literature" and (2) the instruction of textual analysis (or practice of…

  6. Translation Competence and Translation Performance: Lexical, Syntactic and Textual Patterns in Student Translations of a Specialized EU Genre

    ERIC Educational Resources Information Center

    Karoly, Adrienn

    2012-01-01

    This paper reports the findings of a study aiming to reveal the recurring patterns of lexical, syntactic and textual errors in student translations of a specialized EU genre from English into Hungarian. By comparing the student translations to the official translation of the text, this article uncovers the most frequent errors that students made…

  7. Assessing Online Textual Feedback to Support Student Intrinsic Motivation Using a Collaborative Text-Based Dialogue System: A Qualitative Study

    ERIC Educational Resources Information Center

    Shroff, Ronnie H.; Deneen, Christopher

    2011-01-01

    This paper assesses textual feedback to support student intrinsic motivation using a collaborative text-based dialogue system. A research model is presented based on research into intrinsic motivation, and the specific construct of feedback provides a framework for the model. A qualitative research methodology is used to validate the model.…

  8. In-group rationalizations of risk and indoor tanning: A textual analysis of an online forum.

    PubMed

    Carcioppolo, Nick; Chudnovskaya, Elena V; Martinez Gonzalez, Andrea; Stephan, Tyler

    2016-07-01

    Unlike other health behaviors, there does not appear to be a strong relationship between perceived skin cancer risk and reduction or cessation of indoor tanning bed use. This study seeks to address this inconsistency by determining how indoor tanning bed users rationalize skin cancer risk with their tanning behavior. Qualitative textual analysis of indoor tanning message board posts (N = 330) revealed varied perceptions of risk, including acknowledging the risk of indoor tanning; denying or downplaying risk, often citing perceived health benefits associated with tanning; blaming outside forces for cancer, such as lotion or genetics; and fatalistic beliefs about cancer. These results highlight the nuanced relationship between perceived skin cancer risk and indoor tanning bed use. PMID:25550403

  9. [The textual research on the related names of ancient health-care drinks].

    PubMed

    Su, Nuo

    2009-03-01

    There are many kinds of related names of ancient health-care drinks such as tea, tea soup, herb soup, soup, boiled water, thirsty water and cold decoction etc. Following textual research on each connotation of all kinds of names, they have the same aspects as well as different special contents. Among them, the tea soup is some kind of health-care and curative drink, mainly containing tea with other plant decoctions; not only referring to the drinking tea, but also the decoction drunk as tea. The 'tea soup can mostly reflect the original meaning of ancient health-care drinks, and also accord with the understanding of current health-care drinks, thus comprehensively and exactly summarize the content of ancient health-care drinks. PMID:19824369

  10. Figurative language and reading comprehension in American deaf and hard-of-hearing children: textual interactions.

    PubMed

    Rittenhouse, R K; Stearns, K

    1990-12-01

    The limited evidence on figurative language in deaf children, as well as 'professional intuitions', has led those who teach them to conclude that reading comprehension will be significantly complicated by figurative language. However, there are disagreements among practitioners as to how best to manage figurative language when it appears in text. Generally, some sort of textual modification is made, although those for and against 'simplified texts' are split on this issue. Those who favour them suggest either that complex vocabulary and syntax be reconstructed or that they be gradually introduced. However, reformulations are seldom standard nor are the figurative tropes such as metaphor, simile, personification etc. systematically introduced. Those against simplified texts argue that the problem of figurative language control is not one of linguistic complexity, but one of cognitive processing: deaf children can grasp inferred or indirect meaning so long as the referential domain is made clear. Such comprehension comes by way of demonstration, practice and feedback and figurative language need not present a special problem. In this present study, 14 deaf and hard-of-hearing children and youths who had been randomly assigned to one of two groups were given an original story entitled 'Peaches the Cat' and asked to read it. One group read a literal version of the story and one group read a figurative version in which all textual answers to the question were masked with figurative phraseology. Both groups answered the questions above a chance level and the figurative version did not prove to be more difficult than the literal version. The two groups were comparable on hearing loss and on reading and language ability.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:2095841

  11. Instantánea del cáncer de riñón

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de riñón; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  12. Instantánea del cáncer de seno (mama)

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de seno (mama); así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  13. Instantánea del cáncer de tiroides

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de tiroides; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  14. Instantánea del cáncer de vejiga

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de vejiga; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  15. Instantánea del cáncer de pulmón

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de pulmón; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  16. Instantánea del cáncer de páncreas

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de páncreas; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  17. Instantánea del cáncer de cuello uterino

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de cuello uterino; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  18. Instantánea del cáncer de esófago

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de esófago; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  19. Instantánea del cáncer de estómago

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de estómago; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  20. Instantánea del cáncer de ovario

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de ovario; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  1. Instantánea del cáncer de endometrio

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de endometrio; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  2. Instantánea del cáncer de próstata

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de próstata; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  3. MedEvi: Retrieving textual evidence of relations between biomedical concepts from Medline

    PubMed Central

    Kim, Jung-jae; Pȩzik, Piotr; Rebholz-Schuhmann, Dietrich

    2008-01-01

    Summary: Search engines running on MEDLINE abstracts have been widely used by biologists to find publications that are related to their research. The existing search engines such as PubMed, however, have limitations when applied for the task of seeking textual evidence of relations between given concepts. The limitations are mainly due to the problem that the search engines do not effectively deal with multi-term queries which may imply semantic relations between the terms. To address this problem, we present MedEvi, a novel search engine that imposes positional restriction on occurrences matching multi-term queries, based on the observation that terms with semantic relations which are explicitly stated in text are not found too far from each other. MedEvi further identifies additional keywords of biological and statistical significance from local context of matching occurrences in order to help users reformulate their queries for better results. Availability: http://www.ebi.ac.uk/tc-test/textmining/medevi/ Contact: kim@ebi.ac.uk PMID:18400773

  4. Mapping annotations with textual evidence using an scLDA model

    PubMed Central

    Jin, Bo; Chen, Vicky; Chen, Lujia; Lu, Xinghua

    2011-01-01

    Most of the knowledge regarding genes and proteins is stored in biomedical literature as free text. Extracting information from complex biomedical texts demands techniques capable of inferring biological concepts from local text regions and mapping them to controlled vocabularies. To this end, we present a sentence-based correspondence latent Dirichlet allocation (scLDA) model which, when trained with a corpus of PubMed documents with known GO annotations, performs the following tasks: 1) learning major biological concepts from the corpus, 2) inferring the biological concepts existing within text regions (sentences), and 3) identifying the text regions in a document that provides evidence for the observed annotations. When applied to new gene-related documents, a trained scLDA model is capable of predicting GO annotations and identifying text regions as textual evidence supporting the predicted annotations. This study uses GO annotation data as a testbed; the approach can be generalized to other annotated data, such as MeSH and MEDLINE documents. PMID:22195141

  5. The physical activity of parturition in ancient Egypt: textual and epigraphical sources.

    PubMed

    Töpfer, Susanne

    2014-01-01

    Many medical and magical texts concerning childbirth and delivery are known from ancient Egypt. Most of them are spells, incantations, remedies and prescriptions for the woman in labour in order to accelerate the delivery or protect the unborn child and parturient. The medical and magical texts do not contain any descriptions of parturition itself, but there are some literary, astronomical and mythological texts, as well as a few incantations, which describe the biological act of childbirth and also miscarriage in more detail. Besides the textual sources, the decoration of temple walls and mammisis (birth houses), as well as illustrations on a birth brick provide an insight into the moment of delivery. In this paper, I focus on the "scientific"depiction of the biological act of childbirth, on how it is described in non-medical sources. Although the main sources are mythological-theological texts with numerous analogies, it is remarkable how many details they provide. They contain descriptions that would be expected in the context of medical sources. PMID:25481965

  6. Large Scale Near-Duplicate Celebrity Web Images Retrieval Using Visual and Textual Features

    PubMed Central

    Wang, Cheng; Zhang, Xin; Wang, Hui

    2013-01-01

    Near-duplicate image retrieval is a classical research problem in computer vision toward many applications such as image annotation and content-based image retrieval. On the web, near-duplication is more prevalent in queries for celebrities and historical figures which are of particular interest to the end users. Existing methods such as bag-of-visual-words (BoVW) solve this problem mainly by exploiting purely visual features. To overcome this limitation, this paper proposes a novel text-based data-driven reranking framework, which utilizes textual features and is combined with state-of-art BoVW schemes. Under this framework, the input of the retrieval procedure is still only a query image. To verify the proposed approach, a dataset of 2 million images of 1089 different celebrities together with their accompanying texts is constructed. In addition, we comprehensively analyze the different categories of near duplication observed in our constructed dataset. Experimental results on this dataset show that the proposed framework can achieve higher mean average precision (mAP) with an improvement of 21% on average in comparison with the approaches based only on visual features, while does not notably prolong the retrieval time. PMID:24163631

  7. Tonal interface to MacroMolecules (TIMMol): A textual and tonal tool for molecular visualization.

    PubMed

    Cordes, Timothy J; Carlson, C Britt; Forest, Katrina T

    2008-05-01

    We developed the three-dimensional visualization software, Tonal Interface to MacroMolecules or TIMMol, for studying atomic coordinates of protein structures. Key features include audio tones indicating x, y, z location, identification of the cursor location in one-dimensional and three-dimensional space, textual output that can be easily linked to speech or Braille output, and the ability to scroll along the main chain backbone of a protein structure. This program was initially designed for visually impaired users, and it already has shown its effectiveness in helping a blind researcher study X-ray crystal structure data. Subsequently, TIMMol has been enhanced with a graphical display to act as a bridge to ease communication between sighted and visually impaired users as well as to serve users with spatial visualization difficulties. We performed a pilot study to assess the efficacy of the program in conveying three-dimensional information about proteins with and without graphical output to a general scientific audience. Attitudes regarding using TIMMol were assessed using Rasmol, a common visualization package, for comparison. With the use of text and tones exclusively, a majority of users were able to identify specific secondary structure elements, three-dimensional relationships among atoms, and atoms coordinating a ligand. In addition, a majority of users saw benefits in using TIMMol and would recommend it to those having difficulty with standard tools. PMID:21591192

  8. [Textual research on Shi Kan and Shi zai zhi fang (Shi Zaizhi's Prescriptions)].

    PubMed

    Wang, Zhenguo

    2002-07-01

    Shi Kan, also known as Zaizhi, was born in Emei, Sichuan, and Zaizhi was more popularly known. He lived in the Northern Song dynasty, and was a successful candidate in the highest imperial examinations. As a government official, he was promoted to the position of governor. When he cured the constipation of Cai Jing only with a single herb Aster root, people considered that he had excellent medical skill as famous doctor Xu Shuwei. He was one of the representatives who were doctors as well as government officials. His book Shi zai zhi fang (Shi Zaizhi's Prescriptions) was a typical formula work of the Song dynasty. In this book he emphasized the treatment principles on strengthening the vital and dispelling the evil. He also underlined the theory of yunqi (five elements' motion and six kinds of natural factors). He had many new ideas about the application of herbs and pulse - taking. According to the book, Zhi zhai shu lu jie ti (Zhizhai's Interpretation on Collected Books), Shi had a 2 - volume book titled Zhi nan fang (Guide Prescriptions). There were different views on whether Guide Prescriptions was the other name for Shi Zaizhi's Prescriptions. By studying the contents of citations from Shi's Guide Prescriptions quoted in Hong shi ji yan fang (Hong's Collections of Proved Recipes), Quan sheng zhi mi fang (A Guidebook of Recipes for Saving Lives), and by combining it with the textual research made by various scholars of the Qing dynasty, the author claims that Guide Prescriptions is another book rather than the other name of Shi Zaizhi's Prescriptions. PMID:12639444

  9. Aligning ontologies and integrating textual evidence for pathway analysis of microarray data

    SciTech Connect

    Gopalan, Banu; Posse, Christian; Sanfilippo, Antonio P.; Stenzel-Poore, Mary; Stevens, S.L.; Castano, Jose; Beagley, Nathaniel; Riensche, Roderick M.; Baddeley, Bob; Simon, R.P.; Pustejovsky, James

    2006-10-08

    Expression arrays are introducing a paradigmatic change in biology by shifting experimental approaches from single gene studies to genome-level analysis, monitoring the ex-pression levels of several thousands of genes in parallel. The massive amounts of data obtained from the microarray data needs to be integrated and interpreted to infer biological meaning within the context of information-rich pathways. In this paper, we present a methodology that integrates textual information with annotations from cross-referenced ontolo-gies to map genes to pathways in a semi-automated way. We illustrate this approach and compare it favorably to other tools by analyzing the gene expression changes underlying the biological phenomena related to stroke. Stroke is the third leading cause of death and a major disabler in the United States. Through years of study, researchers have amassed a significant knowledge base about stroke, and this knowledge, coupled with new technologies, is providing a wealth of new scientific opportunities. The potential for neu-roprotective stroke therapy is enormous. However, the roles of neurogenesis, angiogenesis, and other proliferative re-sponses in the recovery process following ischemia and the molecular mechanisms that lead to these processes still need to be uncovered. Improved annotation of genomic and pro-teomic data, including annotation of pathways in which genes and proteins are involved, is required to facilitate their interpretation and clinical application. While our approach is not aimed at replacing existing curated pathway databases, it reveals multiple hidden relationships that are not evident with the way these databases analyze functional groupings of genes from the Gene Ontology.

  10. Computers in the Teaching of English as a Foreign Language: Access to the Diversity of Textual Genres and Language Skills

    NASA Astrophysics Data System (ADS)

    Dos Santos, Roberto-Márcio; Sobrinho, Jerônimo Coura

    In the area of language teaching both language skills and textual genres can be worked with simultaneously (thus responding to the Brazilian Curricular Parameters and to the trends in contemporary education, which emphasize contextualized teaching) by means of computers. Computers can make the teaching process dynamic and rich, since they enable the access to the foreign language through virtual environments, which creates a larger number of learning contexts, with all their specific vocabulary and linguistic features in real communication. This study focuses on possible applications of this kind of approach. The computer online is a resource of diverse textual genres and can be an important tool in the language classroom as well as an access to authentic material produced in contextualized practice close to real-life communication. On the other hand, all these materials must be appropriately used without ever worshipping the technology as if it were a miraculous solution. After all, the professional pedagogic skills of the teacher should never be forgotten or taken for granted. In this study, a series of interviews with teachers was carried out - both with Brazilian teachers of the public sector (basic education) and language institutes (private English courses) as well as teacher trainers (university professors), in order to verify if the teachers were prepared to work with informatics in teaching practices, and check the professionals’ views on the subject. The ideas of Maingueneau and Marcuschi about textual genres are a theoretical base in this work, besides the concept of cognitive economy. The text and its typology are focused here as the basic material for teaching English, through digital technologies and hypermedia. The study is also based on Sharma and Barrett’s notion of blended learning as a balanced combination of technological resources and traditional practices in the classroom. Thus, this is an attempt to investigate the relevance of

  11. Shifting Norms and Expectations for Medical School Leaders: A Textual Analysis of Career Advertisements 2000-2004 cf. 2010-2014

    ERIC Educational Resources Information Center

    Gorsky, Diane; MacLeod, Anna

    2016-01-01

    Leadership norms and expectations are continually evolving in higher education. Medical education is no exception to that trend, but shifts over time are intangible and difficult to measure. To explore emerging changes, the authors conducted a textual analysis of published career advertisements from 2000-2004 and 2010-2014. While a number of…

  12. TRAINER Manual for Use with TRAINER: Computer Assisted Learning and Practice Modules. A Textual Representation, Section A: Dialog and Section B: ORBIT.

    ERIC Educational Resources Information Center

    Caruso, Elaine

    This self-instruction guide for online searching using DIALOG or ORBIT search systems, developed at the University of Pittsburgh, is designed to allow users of scientific and technical information to access databases without an intermediary. The guide is segmented into three parts: the basic TRAINER manual and separate textual representations of…

  13. Un Cours de Redaction Axe sur le Processus d'Ecriture et sur la Linguistique Textuelle (A Writing Course Focusing on the Process of Writing and Linguistic Textuality).

    ERIC Educational Resources Information Center

    Lemonnier, France H.; Guimont, Lionel

    1995-01-01

    This paper presents a French-as-a-Second-Language writing course for non-Francophone students at an advanced university level. Because this approach to teaching writing focuses on the writer (and on the reader's expectations), as well as on textuality, the organization (i.e., the architecture) of this course is as complex as writing. (32…

  14. The Textual Abuse of Childhood in the English-Speaking World: The Contribution of Language to the Denial of Children's Rights.

    ERIC Educational Resources Information Center

    Saunders, Bernadette J.; Goddard, Chris

    2001-01-01

    Highlights how language of journalists and academics to describe children's experiences reflects and influences the position and rights accorded to children in the English-speaking world. Contends that children's low status is perpetuated through "textual abuse" in academic literature on children's rights. Maintains that children are objectified…

  15. Donner de la voix et de la plume: Analyse textuelle et creativite (Giving Voice and Written Form: Textual Analysis and Creativity).

    ERIC Educational Resources Information Center

    Kassis-Bocquillon, Paule

    1990-01-01

    A method and activities for approaching textual analysis with language students and making it something other than an academic exercise is discussed and illustrated. The technique uses reading by a variety of methods, oral and quiet, for producing insight into the text. (MSE)

  16. Evaluating the Effects of Massed and Distributed Practice on Acquisition and Maintenance of Tacts and Textual Behavior with Typically Developing Children

    ERIC Educational Resources Information Center

    Haq, Shaji S.; Kodak, Tiffany

    2015-01-01

    This study evaluated the effects of massed and distributed practice on the acquisition of tacts and textual behavior in typically developing children. We compared the effects of massed practice (i.e., consolidating all practice opportunities during the week into a single session) and distributed practice (i.e., distributing all practice…

  17. Richness, Redundancy or Relational Salience? A Comparison of the Effect of Textual and Aural Feedback Modes on Knowledge Elaboration in Higher Education Students' Work

    ERIC Educational Resources Information Center

    Gleaves, Alan; Walker, Caroline

    2013-01-01

    This study examines the effects of formative assessment feedback commentaries utilizing textual and aural media on the quality of knowledge elaboration within the written work of a sample of 104 higher education students. A randomized, mixed methodological approach was adopted that examined changes within the students' work over a period of one…

  18. Combining Hierarchical and Associative Gene Ontology Relations with Textual Evidence in Estimating Gene and Gene Product Similarity

    SciTech Connect

    Sanfilippo, Antonio P.; Posse, Christian; Gopalan, Banu; Riensche, Roderick M.; Beagley, Nathaniel; Baddeley, Bob L.; Tratz, Stephen C.; Gregory, Michelle L.

    2007-03-01

    Gene and gene product similarity is a fundamental diagnostic measure in analyzing biological data and constructing predictive models for functional genomics. With the rising influence of the Gene Ontology, two complementary approaches have emerged where the similarity between two genes or gene products is obtained by comparing Gene Ontology (GO) annotations associated with the genes or gene products. One approach captures GO-based similarity in terms of hierarchical relations within each gene subontology. The other approach identifies GO-based similarity in terms of associative relations across the three gene subontologies. We propose a novel methodology where the two approaches can be merged with ensuing benefits in coverage and accuracy, and demonstrate that further improvements can be obtained by integrating textual evidence extracted from relevant biomedical literature.

  19. Evaluating the effects of massed and distributed practice on acquisition and maintenance of tacts and textual behavior with typically developing children.

    PubMed

    Haq, Shaji S; Kodak, Tiffany

    2015-01-01

    This study evaluated the effects of massed and distributed practice on the acquisition of tacts and textual behavior in typically developing children. We compared the effects of massed practice (i.e., consolidating all practice opportunities during the week into a single session) and distributed practice (i.e., distributing all practice opportunities across 4 sessions during the week) on the acquisition of textual behavior in English, tacting pictures of common nouns in Spanish, and textual behavior in Spanish using an adapted alternating treatments design embedded within a multiple probe design. We also examined correct responding during probes that (a) excluded prompts and reinforcement and (b) occurred 48 hr after training each week. The results indicated that distributed practice was the more efficient training format. Maintenance data collected up to 4 weeks after training also indicated that the participants consistently displayed higher levels of correct responding to targets that had been trained in distributed format. We discuss implications for practice and potential areas for future research. PMID:25376717

  20. Web-Based Textual Analysis of Free-Text Patient Experience Comments From a Survey in Primary Care

    PubMed Central

    Davey, Antoinette; Elliott, Marc N; Roberts, Martin; Roland, Martin; Brown, Finlay; Burt, Jenni; Boiko, Olga; Campbell, John

    2015-01-01

    Background Open-ended questions eliciting free-text comments have been widely adopted in surveys of patient experience. Analysis of free text comments can provide deeper or new insight, identify areas for action, and initiate further investigation. Also, they may be a promising way to progress from documentation of patient experience to achieving quality improvement. The usual methods of analyzing free-text comments are known to be time and resource intensive. To efficiently deal with a large amount of free-text, new methods of rapidly summarizing and characterizing the text are being explored. Objective The aim of this study was to investigate the feasibility of using freely available Web-based text processing tools (text clouds, distinctive word extraction, key words in context) for extracting useful information from large amounts of free-text commentary about patient experience, as an alternative to more resource intensive analytic methods. Methods We collected free-text responses to a broad, open-ended question on patients’ experience of primary care in a cross-sectional postal survey of patients recently consulting doctors in 25 English general practices. We encoded the responses to text files which were then uploaded to three Web-based textual processing tools. The tools we used were two text cloud creators: TagCrowd for unigrams, and Many Eyes for bigrams; and Voyant Tools, a Web-based reading tool that can extract distinctive words and perform Keyword in Context (KWIC) analysis. The association of patients’ experience scores with the occurrence of certain words was tested with logistic regression analysis. KWIC analysis was also performed to gain insight into the use of a significant word. Results In total, 3426 free-text responses were received from 7721 patients (comment rate: 44.4%). The five most frequent words in the patients’ comments were “doctor”, “appointment”, “surgery”, “practice”, and “time”. The three most frequent two

  1. Teaching Generative Reading Via Recombination of Minimal Textual Units: A Legacy of Verbal Behavior to Children in Brazil

    PubMed Central

    de Souza, Deisy G.; de Rose, Julio C.; Faleiros, Thais C.; Bortoloti, Renato; Hanna, Elenice Seixas; McIlvane, William J.

    2009-01-01

    This paper reports results of two studies that sought to teach generative reading skills to a large group of Brazilian children who were exhibiting protracted failure in school. Inspired by Skinner’s analysis of verbal relations and minimal verbal units, the methodology took advantage of certain characteristics of Portuguese. Many words in this language are comprised of two-letter syllabic units (e.g., BO+LA= ball, CA+BO= handle, LA+TA= can) that can be recombined to form new words (e.g., BOCA= mouth, BOTA= boot), thus establishing a route to generative reading via recombinative generalization. Such syllabic units were incorporated within curricular framework that used matching-to-sample and learning by exclusion methods to teach matching relations involving pictures, printed and spoken words, and printed and spoken syllables. Study 1 was conducted within a university-based learning center that maintained certain aspects of laboratory conditions. It showed that teaching textual relations between dictated and printed syllables could control procedurally the inter- and intra-participant variability observed in past studies that lacked this feature -resulting in virtually universally positive teaching outcomes. Study 2 was conducted in a public school programs that applied the same basic training methodology. Positive training outcomes in an experimental group were approximately 3–5 times greater than that in a placebo control group. Together, these studies illustrate that the functional analysis in Verbal Behavior is having a direct impact in educational science in Brazil. It has led to procedures that can be effectively translated from the laboratory to the community via delivery systems that can be implemented in the developing world. PMID:19960112

  2. Textual analysis of sugar industry influence on the World Health Organization’s 2015 sugars intake guideline

    PubMed Central

    Reeves, Aaron; Loopstra, Rachel; McKee, Martin

    2016-01-01

    Abstract Objective To determine whether sugar industry-related organizations influenced textual changes between the draft and final versions of the World Health Organization’s (WHO’s) 2015 guideline Sugars intake for adults and children. Methods Stakeholder consultation submissions on the draft guideline from seven sugar industry-related and 10 public health organizations were assessed using the Wordscores program. Document scores were rescaled using the Martin–Vanberg transformation to improve comparability. Draft and final guidelines were compared to identify changes influenced by the sugar industry and public health organizations. Findings There was a small shift in transformed Wordscores score between the draft and final guidelines, from 0.25 to 0.24, towards the industry position. The change was linked to increased use of the word “low” to describe the quality of the evidence, consistent with industry arguments. There was also a shift from use of the word “consumption” to “intake”, irrespective of policy position. Scores for World Sugar Research Organisation and Sugar Nutrition UK submissions ( 0.11 and 0.18, respectively) represented strong pro-industry positions and scores for European Public Health Alliance and Wemos submissions (1.00 and 0.88, respectively) represented the strongest public health positions. Industry tactics included challenging the quality of the evidence, distinguishing between different types of sugar and advocating harm reduction. Conclusion There was little change between draft and final versions of the WHO sugars intake guideline 2015, following industry consultation. The main change was linked to emphasizing the low quality of the evidence on sugar’s adverse effects. Guideline development appeared relatively resistant to industry influence at the stakeholder consultation stage. PMID:27516634

  3. Estudio multifrecuencia del medio interestelar cercano a HD 192281

    NASA Astrophysics Data System (ADS)

    Arnal, E. M.; Cappa, C.; Cichowolski, S.; Pineault, S.; St-Louis, N.

    Una de las causas que modifica la estructura y dinámica del medio interestelar es la acción que los vientos de las estrellas de gran masa ejercen sobre el mismo. En este trabajo, mediante el uso de datos interferométricos obtenidos en la banda de radio en la transición de 21-cm del Hidrógeno neutro y de imágenes de la emisión de continuo en las bandas de 408 y 1420 MHz, de imágenes HIRES del satélite IRAS en 60 y 100 micrones, y de observaciones de continuo obtenidas con radiotelescopios de disco simple en 2695, 4850 y 8350 MHz se ha realizado un estudio multifrecuencia de los efectos que los vientos estelares de HD 192281, una estrella de tipo espectral O5 Vn((f))p, han tenido sobre el medio interestelar que rodea a la misma.

  4. On textual and contextual position of the ophthalmological treatise of bodhisattva nāgārjuna.

    PubMed

    Kim, Seongsu; Kang, Sungyong

    2013-04-01

    regard. Thereafter, Tài píng shèng huì fāng (Holy Prescriptions for Universal Relief) compiled by a national agency at the beginning of the Song Dynasty period introduced Lóng shù pú sà yăn lùn without clear indication of the reference. Contemporary with this book, many ophthalmological books such as Mì chuán yăn kē lóng mù lùn(Longmu's Ophthalmology Secretly Handed Down) were published. As Chinese culture was spreading out into surrounding countries, medical knowledge was also introduced to Korean peninsula and Japan. The ophthalmological knowledge contained in Lóng shù pú sà yăn lùn was also reflected and some parts of it were introduced in I shin bō in Japan. Based on the policy decision of King Sejong, the fourth king of Joseon Dynasty, large scaled promoting projects of medical knowledge was established. It is notable that the Ui bang ryu chwi compiled as a result of the synthesis of the medical treatises available at that time initiated by King Sejong contained a considerable part of Lóng shù pú sà yăn lùn in reedited form that had already passed into oblivion in China. The intellectuals in Joseon Dynasty who participated in the compilation of Ui bang ryu chwi not only indicated that Lóng shù pú sà yăn lùn was a medical text published in the times of Wei-Qin and South & North Dynasties in China but also clearly indicated the textual reference and left the original text for later generation without modifying the contents. According to the Ui bang ryu chwi, the Lóng shù pú sà yăn lùn indicated that the core causes of eye diseases were heat, winds, and three body fluids(trido a) and contained the analyses of symptoms, related treatments, and several analyses of wrong treatments. In addition, Lóng shù pú sà yăn lùn explained diverse eye diseases through more than 30 medical treatments. In particular, this book accurately described golden needle acupuncture for treatment of a Nèi-zhàng understood to be cataract

  5. [Textual research on luohuangzi].

    PubMed

    Zhang, M

    1991-09-01

    By studying ancient and modern literatures and observing the material object, we have come to the conclusion that the fruit called "luohuangzi" in ancient times should be the seed of Sterculia nobilis rather than Tamarindus indica. We therefore suggest that "luohuangzi" be no longer used as another name for T. indica, and, in order to eliminate the confusion about the name and material object of "luohuangzi". Tamarindus should be called the "genus Shuandou" in Chinese instead of the "genus Luowangzi". PMID:1804193

  6. Textual Data in Psychiatry

    PubMed Central

    Yang, Suzanne; Mulvey, Edward P.; Falissard, Bruno

    2013-01-01

    Personal meaning in subjective experience is a key element in the treatment of persons with mental disorders. Open-response speech samples would appear to be suitable for studying this type of subjective experience, but there are still important challenges in using language as data. Scientific principles involved in sample size calculation, validity, and reliability may be applicable, by analogy, to data collected in the form of words. We describe a rationale for including computer-assisted techniques as one step of a qualitative analysis procedure that includes manual reading. Clarification of a framework for including language as data in psychiatric research may allow us to more effectively bridge biological and psychometric research with clinical practice, a setting where the patient’s clinical “data” are, in large part, conveyed in words. PMID:22850301

  7. Into the (Textual) West

    ERIC Educational Resources Information Center

    Gannon, Susanne

    2009-01-01

    A critical/creative paradigm in contemporary English carries with it an imperative that students should be given opportunities for deep engagement with texts relevant to what matters in their everyday lives. In this paper, I argue that the materiality of everyday life includes the physical and geographic places where we live. When students live in…

  8. Cinemática y masas de agujeros negros en galaxias activas del tipo "Narrow Line Seyfert 1"

    NASA Astrophysics Data System (ADS)

    Oío, G.; Schmidt, E.; Vega Neme, L. R.

    We apply a spectral synthesis method to Narrow Line Seyfert 1 active galax- ies with public spectra available. Our goal will be to obtain the stellar ve- locity dispersions, and then the central black hole masses via the Tremaine relation. We comment several problems we found in fitting this type of objects and the possibility of obtaining masses through the emission lines. FULL TEXT IN SPANISH

  9. Home-Type Activities at the Day Care Center. (Tipos De Actividades Del Hogar En El Centro De Cuidado Diario.)

    ERIC Educational Resources Information Center

    Aaronson, May; Moberg, Patricia E.

    This paper argues that home activities comprise a valuable unplanned curriculum and that many of these activities can be transferred to the day care center. It is suggested that these activities foster a closer relationship between child and caregiver and bridge the gap between familiar home environment and novel day care setting. Home activities…

  10. Relaciones fundamentales de la población de galaxias de tipo temprano del cúmulo de Antlia

    NASA Astrophysics Data System (ADS)

    Calderón, J. P.; Bassino, L. P.; Cellone, S. A.; Smith Castelli, A. V.; Caso, J. P.

    We present the results of a study of more than 100 early-type galaxies in Antlia Cluster, that span from giant ellipticals to dwarf ellipticals, covering a magnitude range of 11 magnitudes (M_{V_T} = -22 to -11). We perform surface photometry of these galaxies, and their total magnitudes, surface brightnesses and radii are determined on the basis of the Sérsic law fits. Finally, the fundamental relations between them are analyzed. FULL TEXT IN SPANISH

  11. Qué tipos hay de estudios clínicos

    Cancer.gov

    Información sobre los diversos tipos de estudios clínicos de cáncer, como son los estudios de tratamiento, de prevención, de exámenes selectivos de detección, de cuidados médicos de apoyo y de cuidados paliativos.

  12. Archivo de placas astrométricas del Observatorio de La Plata

    NASA Astrophysics Data System (ADS)

    di Sisto, R.; Orellana, R. B.

    Se ha realizado una base de datos con las placas fotográficas obtenidas con el Astrográfico del Observatorio de La Plata. Se han clasificado un total de 3000 placas obtenidas para asteroides y cometas. El acceso a la base de datos se hará por FTP y la misma contendrá la siguiente información: fecha y tiempo de exposición, coordenadas del centro de placa, tipo de emulsión fotográfica, estado de la placa, objeto fotografiado.

  13. Presupposti teorici per un progetto di insegnamento della traduzione dalla lingua straniera basato sull'analisi testuale (Theoretical Presuppositions for a Project to Teach Translation from a Foreign Language Based on Textual Analysis).

    ERIC Educational Resources Information Center

    Horrakh, Livio

    1987-01-01

    Discusses an approach to translation based on textual linguistics. The student/translator first looks at the foreign language text as a whole, then analyzes its parts, and finally arrives at a new synthesis (the translation) that is comparable to the original text. (CFM)

  14. [The decipher, annotation and textual researches of 7 anti-dysentery prescriptions in the Tangut medical documents unearthed in Khara-Khoto].

    PubMed

    Tang, Xiao-Long; Liu, Jing-Yun; Zhang, Ru-Qing

    2013-05-01

    There were 7 anti-dysentery prescriptions in the Tangut medical documents unearthed in Khara-Khoto, preserved in Russia, which were deciphered, annotated and textually researched based on the Tangut tool books like Wenhai (Word Ocean), Tongyin (Homophones), and Fan han he shi zhang zhong zhu (A Tangut-Chinese Timely Gem Dictionary), combining with classical medical documents and application of knowledge of ancient Chinese language. It can be sure that these prescriptions came from the central plains of China during the Song Dynasty, which were made use of by the prescriptions as they were by the physicians of the Western Xia regime, either made modifications and adjustments or without any change. For example, local foods like local sugar and cheese were added. As for the administration and dosage, again, they were applied by following the original one or changing a little according to the local diet customs. PMID:24060025

  15. Protótipo do primeiro interferômetro brasileiro - BDA

    NASA Astrophysics Data System (ADS)

    Cecatto, J. R.; Fernandes, F. C. R.; Neri, J. A. C. F.; Bethi, N.; Felipini, N. S.; Madsen, F. R. H.; Andrade, M. C.; Soares, A. C.; Alonso, E. M. B., Sawant, H. S.

    2004-04-01

    A interferometria é uma poderosa ferramenta usada para investigar estruturas espaciais de fontes astrofísicas fornecendo uma riqueza de detalhes inatingível pelas técnicas convencionais de imageamento. Em particular, a interferometria com ondas de rádio abre o horizonte de conhecimento do Universo nesta ampla banda do espectro eletromagnético, que vai de cerca de 20 kHz até centenas de GHz já próximo ao infravermelho, e que está acessível a partir de instrumentos instalados em solo. Neste trabalho, apresentamos o interferômetro designado por Arranjo Decimétrico Brasileiro (BDA). Trata-se do primeiro interferômetro a ser desenvolvido no Brasil e América Latina que já está em operação na fase de protótipo. Apresentamos o desenvolvimento realizado até o momento, o sítio de instalação do instrumento, o protótipo e os principais resultados dos testes de sua operação, as perspectivas futuras e a ciência a ser desenvolvida com o instrumento nas fases II e III. Neste trabalho é dada ênfase ao desenvolvimento, testes de operação e principais resultados do protótipo. É discutida brevemente a ciência que pode ser feita com o instrumento. Tanto os detalhes técnicos quanto os principais parâmetros estimados para o instrumento nas próximas fases de desenvolvimento e o desempenho do protótipo serão publicados em breve.

  16. A Mobile Phone App Intervention Targeting Fruit and Vegetable Consumption: The Efficacy of Textual and Auditory Tailored Health Information Tested in a Randomized Controlled Trial

    PubMed Central

    2016-01-01

    Background Mobile phone apps are increasingly used to deliver health interventions, which provide the opportunity to present health information via different communication modes. However, scientific evidence regarding the effects of such health apps is scarce. Objective In a randomized controlled trial, we tested the efficacy of a 6-month intervention delivered via a mobile phone app that communicated either textual or auditory tailored health information aimed at stimulating fruit and vegetable intake. A control condition in which no health information was given was added. Perceived own health and health literacy were included as moderators to assess for which groups the interventions could possibly lead to health behavior change. Methods After downloading the mobile phone app, respondents were exposed monthly to either text-based or audio-based tailored health information and feedback over a period of 6 months via the mobile phone app. In addition, respondents in the control condition only completed the baseline and posttest measures. Within a community sample (online recruitment), self-reported fruit and vegetable intake at 6-month follow-up was our primary outcome measure. Results In total, 146 respondents (ranging from 40 to 58 per condition) completed the study (attrition rate 55%). A significant main effect of condition was found on fruit intake (P=.049, partial η2=0.04). A higher fruit intake was found after exposure to the auditory information, especially in recipients with a poor perceived own health (P=.003, partial η2=0.08). In addition, health literacy moderated the effect of condition on vegetable intake 6 months later (P<.001, partial η2=.11). A higher vegetable intake was found for recipients with high health literacy after exposure to the textual or auditory intervention compared to the control condition (contrasts P=.07 and P=.004, respectively). In the case of relatively low health literacy, vegetable intake was the highest in the control

  17. Preguntas y respuestas acerca del Estudio del

    Cancer.gov

    El Estudio del Tamoxifeno y Raloxifeno (STAR, por sus siglas en ingls) es un estudio clnico (un estudio de investigacin conducido con voluntarios) diseado para ver cómo el medicamento raloxifeno (Evista) se compara con el medicamento tamoxifeno (Nolvadex)

  18. Estudio multifrecuencia del medio interestelar cercano a HD 192281

    NASA Astrophysics Data System (ADS)

    Arnal, E. M.; Cappa, C. E.; Cichowolski, S.; Pineault, S.; St-Louis, N.

    Una de las causas que modifica la estructura y dinámica del medio interestelar es la acción que los vientos de las estrellas de gran masa ejercen sobre el mismo. En este trabajo, mediante el uso de datos interferométricos obtenidos en la banda de radio en la transición de λ˜21-cm del hidrógeno neutro y de imágenes de la emisión de continuo en las bandas de 408 y 1420 MHz, de imágenes HIRES del satélite IRAS en 60 y 100μm, y de observaciones de continuo obtenidas con radiotelescopios de disco simple en 2695, 4850 y 8350 MHz se ha realizado un estudio multifrecuencia de los efectos que los vientos estelares de HD 192281, una estrella de tipo espectral O5,Vn((f))p, han tenido sobre el medio interestelar que rodea a la misma.

  19. Il problema del litio.

    NASA Astrophysics Data System (ADS)

    D'Antona, F.

    1995-03-01

    Contents: 1. Introduzione. 2. La nucleosintesi del Big Bang. 3. Il litio nelle stelle di popolazione II. 4. I modelli stellari standard. 5. Il litio negli ammassi aperti. 6. Meccanismi di distruzione "non standard". 7. I modelli non-standard applicati alla popolazione II. 8. L'evoluzione Galattica del litio. 9. Quali stelle producono litio? 10. Il litio come elemento chiave per dare un nome agli oggetti stellari più minuscoli. 11. Conclusioni.

  20. Espectroscopia del Cometa Halley

    NASA Astrophysics Data System (ADS)

    Naranjo, O.; Fuenmayor, F.; Ferrin, L.; Bulka, P.; Mendoza, C.

    1987-05-01

    Se reportan observaciones espectroscópicas del cometa Halley. Los espectros fueron tomados usando el espectrógrafo del telescopio reflector de 1 metro del Observatorio Nacional de Venezuela. Se utilizó óptica azul, con una red de difracción de 600 lineas/min, obteniéndose una dispersión de 74.2 A/mm y una resolución de 2.5 A, en el rango espectral de 3500 a 6500 A. Seis placas fueron tomadas con emulsión IIa-O y dos con IIa-D. Los tiempos de exposición fueron entre 10 y 150 minutos. El cometa se encontraba entre 0.70 y 1.04 UA del Sol, y entre 1.28 y 0.73 UA de la Tierra. Las emisiones más prominentes en el espectro, son las del CN, C2, y C3. Otras emisiones detectadas corresponden a CH, NH2 y Na. Los espectros muestran un fuerte continuo, indicando un contenido significativo de polvo. Se detectó mayor intensidad del contínuo, en la dirección anti solar, lo cual es evidencia de la cola de polvo.

  1. Local structure of spin Peierls compound TiPO4: 47/49Ti and 31P NMR study

    NASA Astrophysics Data System (ADS)

    Stern, Raivo; Heinmaa, Ivo; Leitmäe, Alexander; Joon, Enno; Tsirlin, Alexander; Kremer, Reinhard; Glaum, Robert

    TiPO4 structure is made of slightly corrugated TiO2 ribbon chains of edge-sharing TiO6 octahedra. The almost perfect 1D spin 1/2 Ti3 + chains are well separated by PO4 tetrahedra. By magnetic susceptibility and MAS-NMR measurements [1] it was shown that TiPO4 has nonmagnetic singlet ground state with remarkably high Spin-Peierls (SP) transition temperature. The high-T magnetic susceptibility of TiPO4 follows well that of a S =1/2 Heisenberg chain with very strong nearest-neighbor AF spin-exchange coupling constant of J =965K. On cooling TiPO4 shows two successive phase transitions at 111K and 74K, with incommensurate (IC) SP phase between them. We studied local structure and dynamics in TiPO4 single crystal using 47/49Ti and 31P NMR in the temperature range 40K to 300K, and determined the principal values and orientation of the magnetic shift tensors for 31P and 47,49Ti nuclei. Since 47,49Ti (S =5/2 and S =7/2, respectively) have quadrupolar moments, we also found the principal axis values and orientations of the electric field gradient (efg) tensor in SP phase and at 295K. In SP phase the structure contains 2 magnetically inequivalent P sites and only one Ti site. From the T-dependence of the relaxation rate of 31P and 47Ti nuclei we determined activation energy Ea = 550 K for spin excitations in SP phase. J. Law et al ., PRB 83, 180414(R) (2011).

  2. PREVENCIÓN DEL VIH/SIDA EN LOS CIRCUITOS DE LEVANTE HSH: UNA ASIGNATURA PENDIENTE.

    PubMed

    Barreda, Victoria; Carballo-Dieguez, Alex; Marone, Rubén; Balán, Iván; Pando, María Ángeles; Avila, María Mercedes

    2010-12-01

    A partir de un relevamiento de tipo etnográfico, se describen lugares de encuentro de HSH en la Ciudad de Buenos Aires y sus prácticas sexuales. El reconocimiento de tales espacios, así como las características que asumen en ellos los encuentros sexuales entre los HSH, plantean obstáculos específicos en la adopción de comportamientos preventivos y, asimismo, generan nuevos desafíos para las actividades de prevención. Se plantean las dificultades y debates conceptuales que la misma categoría presenta, y sus consecuencias en el abordaje preventivo y teórico-metodológico para las ciencias sociales. Además, se proponen nuevos interrogantes acerca de los alcances y las limitaciones del modelo preventivo del VIH/Sida para HSH. PMID:21874154

  3. Aztec homosexuality: the textual evidence.

    PubMed

    Kimball, G

    1993-01-01

    Male and female homosexuality among the Aztecs during the period immediately prior to the Spanish Conquest has been studied infrequently, even though a Nahuatl document, the Florentine Codex, written shortly after the Spanish Conquest, contains a number of texts on the subject. The Florentine Codex has been translated into English; however, the translators use biased and erroneous translations in the sections of the manuscript which mention homosexuality, and the actual meaning is unavailable to anyone who does not know Nahuatl. This paper is a new translation and an introductory study of the available texts on homosexuality in the Florentine Codex. The attitudes of the Aztecs toward homosexual men and women can be inferred from these texts, and there are tantalizing fragments which given an indication of how homosexuality fit into Aztec society. PMID:8113605

  4. [Textual research of Bencaogangmu Yizhilu].

    PubMed

    Lu, Xiang; Wang, Xu-Guang; Deng, Yong; Zhao, Li; Xu, Shi-Hai; Zhang, Xing-Xing; Zhang, Ruo-Ting

    2012-03-01

    Bencaogangmu Yizhilu was compiled by DAI Baoyuan according to Bencao Gangmu in the late Qing dynasty. Due to the limited circulation of the book, it was little studied by people in later ages. Errors could be found concerning the book's content, editions and the author's life. After in-depth research, we concluded that the author's name was Baoyuan (courtesy name Xintian and pseudonym Shouyu). He was born about in 1818 and the year of death was unclear. Compilation of the book was completed in 1885 and the book was published in 1887. Recording 2240 kinds of herbs, the book included 8 volumes, 7 of which were text and the 8(th) volume was the index. It has two editions-the Wu Yuansi added Shanfang printed edition (the 13th year of the Guangxu Period, 1887) and the copy edition of the Qing dynasty. PMID:22782029

  5. Textual Encounters and Pedagogic Interventions

    ERIC Educational Resources Information Center

    Vicars, Mark

    2009-01-01

    School, typically, is no place to be caught being queer and knowledge about homosexuality for the majority of young lesbian, gay and bisexual people is routinely constructed within communities of practice. In this paper, I draw upon my own and others' literacy practices to show how our identities and readings of texts were framed by being…

  6. 41. DISCOVERY, SEARCH, AND COMMUNICATION OF TEXTUAL KNOWLEDGE RESOURCES IN DISTRIBUTED SYSTEMS a. Discovering and Utilizing Knowledge Sources for Metasearch Knowledge Systems

    SciTech Connect

    Zamora, Antonio

    2008-03-18

    Advanced Natural Language Processing Tools for Web Information Retrieval, Content Analysis, and Synthesis. The goal of this SBIR was to implement and evaluate several advanced Natural Language Processing (NLP) tools and techniques to enhance the precision and relevance of search results by analyzing and augmenting search queries and by helping to organize the search output obtained from heterogeneous databases and web pages containing textual information of interest to DOE and the scientific-technical user communities in general. The SBIR investigated 1) the incorporation of spelling checkers in search applications, 2) identification of significant phrases and concepts using a combination of linguistic and statistical techniques, and 3) enhancement of the query interface and search retrieval results through the use of semantic resources, such as thesauri. A search program with a flexible query interface was developed to search reference databases with the objective of enhancing search results from web queries or queries of specialized search systems such as DOE's Information Bridge. The DOE ETDE/INIS Joint Thesaurus was processed to create a searchable database. Term frequencies and term co-occurrences were used to enhance the web information retrieval by providing algorithmically-derived objective criteria to organize relevant documents into clusters containing significant terms. A thesaurus provides an authoritative overview and classification of a field of knowledge. By organizing the results of a search using the thesaurus terminology, the output is more meaningful than when the results are just organized based on the terms that co-occur in the retrieved documents, some of which may not be significant. An attempt was made to take advantage of the hierarchy provided by broader and narrower terms, as well as other field-specific information in the thesauri. The search program uses linguistic morphological routines to find relevant entries regardless of whether

  7. Nevado del Huila, Columbia

    NASA Technical Reports Server (NTRS)

    2007-01-01

    Nevado del Huila Volcano in Colombia is actually a volcanic chain running north to south, capped by a glacier. With peaks ranging in height from 2,600 to 5,780 meters (8,530 to 18,960 feet), Nevado del Huila is a stratovolcano composed of alternating layers of hardened lava, solidified ash, and volcanic rocks. Its first recorded eruption occurred in the mid-sixteenth century. The long-dormant volcano erupted again in mid-April 2007. A few months before the eruption, the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on NASA's Terra satellite captured this image of Nevado del Huila, on February 23, 2007. In this image, the bright white area just east of the central summit is ice. Immediately west of the summit are bare rocks, appearing as blue-gray. West of those rocks, white reappears, but this patch of white results from clouds hovering in the nearby valley. In the east, the colors turn to brown (indicating bare rock) and bright green (indicating vegetation). ASTER photographed Nevado del Huila near the end of a long phase of quietude. On April 17, 2007, local authorities recorded seismic activity associated with rock fracturing on the volcano's central summit, according to the ReliefWeb Website. Activity intensified the following day with an eruption and mudflows, forcing thousands of nearby residents to evacuate. As the Associated Press reported, the eruption caused avalanches and floods that wiped away both houses and bridges. It marked the volcano's first recorded eruption since the Spanish colonized the area five centuries earlier. NASA image created by Jesse Allen, using data provided courtesy of the NASA/GSFC/MITI/ERSDAC/JAROS, and U.S./Japan ASTER Science Team.

  8. Comportamiento del Helio en estrellas químicamente peculiares

    NASA Astrophysics Data System (ADS)

    Malaroda, S. M.; López García, Z.; Leone, F.; Catalano, F.

    Las estrellas químicamente peculiares (CP) se caracterizan por tener deficiencias y sobreabundancias de algunos elementos químicos de hasta 106 veces la abundancia solar. Además presentan variaciones en las líneas espectrales. Se piensa que ello se debe a que los campos magnéticos presentes en este tipo de estrellas son principalmente dipolares, con un eje de simetría diferente del eje de rotación. La distribución de los elementos sobreabundantes y deficientes no es homogénea sobre la superficie estelar y las variaciones observadas serían una consecuencia directa de la rotación estelar. Entre los elementos con abundancia anómala se encuentra el Helio, cuyas líneas tienen intensidades que no son consistentes con una abundancia normal, que no puede ser determinada del modo usual, o sea, considerando una atmósfera con composición solar. Con el fin de determinar la abundancia de este elemento, se inició un estudio de estrellas anómalas de Helio, Hew y He strong. Además se determinarán las abundancias de otros elementos anómalos como ser el Si, Cr, Mg, Mn y Fe. Las mismas se determinan del modo tradicional, o sea: a) medida de los anchos equivalentes de las líneas de los distintos elementos analizados; b) adopción de la temperatura efectiva, gravedad y abundancia del Helio; c) cálculo del modelo de atmósfera d) comparación con las observaciones y reinicio de un proceso iterativo hasta lograr un acuerdo entre todos los parámetros analizados. Las observaciones se llevaron a cabo en el Complejo Astronómico El Leoncito. Se observaron setenta y ocho estrellas anómalas de Helio. En este momento se está procediendo a calcular las abundancias correspondientes a los distintos elementos químicos. Para ello se hace uso de los modelos de Kurucz, ATLAS9. Los cálculos NLTE de las líneas de Helio se llevan a cabo con el programa MULTI y se compararán con los realizados con el programa WIDTH9 de Kurucz (LTE), con el objeto de resaltar la importancia de

  9. Estudo de soluções locais e cosmológicas em teorias do tipo tensor-escalar

    NASA Astrophysics Data System (ADS)

    Silva E Costa, S.

    2003-08-01

    Teorias do tipo tensor-escalar são a mais simples extensão possí vel da Relatividade Geral. Nessas teorias, cujo modelo padrão é a teoria de Brans-Dicke, a curvatura do espaço-tempo, descrita por componentes tensoriais, aparece acoplada a um campo escalar que, de certo modo, representa uma variação na constante de acoplamento da gravitação. Tais teorias apresentam soluções locais e cosmológicas que, em determinados limites, recaem nas apresentadas pela Relatividade Geral, mas que em outros limites trazem novidades, tais como conseqüências observacionais da evolução de flutuações primordiais distintas daquelas previstas pela Relatividade Geral (ver, por ex., Nagata et al., PRD 66, p. 103510 (2002)). Graças a esta possibilidade de trazer à luz novidades em relação à gravitação, teorias do tipo tensor-escalar podem ser vistas como um interessante campo alternativo de pesquisas para soluções dos problemas de massa faltante (ou escura) e/ou energia escura. Seguindo tal linha, este trabalho, ainda em sua fase inicial, apresenta soluções gerais de teorias do tipo tensor-escalar para diversas situações, verificando-se em que consiste a divergência dessas soluções dos casos tradicionais possí veis na Relatividade Geral. Como exemplos das soluções aqui apresentadas pode-se destacar uma expressão geral para diferentes soluções cosmológicas englobando diferentes tipos de matéria (representados por diferentes equações de estado), e a expressão para uma solução local representando um buraco negro com rotação, similar à solução de Kerr da Relatividade Geral. Por fim, é importante ressaltar que, embora aqui apresentem-se poucos resultados novos, na literatura sobre o assunto a maior parte das soluções apresentadas limita-se a uns poucos casos especí ficos, tal como soluções cosmológicas apenas com curvatura nula, e que mesmo as soluções disponí veis são, em geral, pouco divulgadas e, portanto, pouco conhecidas, e

  10. PREVENCIÓN DEL VIH/SIDA EN LOS CIRCUITOS DE LEVANTE HSH: UNA ASIGNATURA PENDIENTE1

    PubMed Central

    Barreda, Victoria; Carballo-Dieguez, Alex; Marone, Rubén; Balán, Iván; Pando, María Ángeles; Ávila, María Mercedes

    2011-01-01

    Resumen A partir de un relevamiento de tipo etnográfico, se describen lugares de encuentro de HSH en la Ciudad de Buenos Aires y sus prácticas sexuales. El reconocimiento de tales espacios, así como las características que asumen en ellos los encuentros sexuales entre los HSH, plantean obstáculos específicos en la adopción de comportamientos preventivos y, asimismo, generan nuevos desafíos para las actividades de prevención. Se plantean las dificultades y debates conceptuales que la misma categoría presenta, y sus consecuencias en el abordaje preventivo y teórico-metodológico para las ciencias sociales. Además, se proponen nuevos interrogantes acerca de los alcances y las limitaciones del modelo preventivo del VIH/Sida para HSH. PMID:21874154

  11. Ácaros del mango

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Los ácaros constituyen un grupo abundante y diverso que ocupa diferentes hábitats en árboles frutales y la estructura y disposición del follaje y ramas del mango, contribuyen significativamente a que se presente gran diversidad de ácaros benéficos y dañinos asociados a esta especie frutal. En Colomb...

  12. Estudio multiespectral del remanente de supernova W 28

    NASA Astrophysics Data System (ADS)

    Dubner, G.; Velázquez, P.; Castelletti, G.

    Se presentan observaciones en continuo de radio con muy alta resolución angular y sensibilidad del remanente de supernova (RSN) W28. Las observaciones fueron realizadas con el interferómetro Very Large Array (Estados Unidos), en las configuraciones C y D, en 1415 y 324 MHz. Por la gran extensión de este remanente (diámetro ~ 1o), las observaciones en 1415 MHz se realizaron en modo mosaico, combinando 48 apuntamientos diferentes en una única imagen. En ambas frecuencias los datos se procesaron con el agregado de observaciones de menor resolución angular, a fin de recuperar información en todas las frecuencias espaciales y obtener estimaciones precisas de densidad de flujo. Las imágenes resultantes muestran por primera vez la presencia de extensiones con forma de arco, cuya naturaleza se investiga. Las observaciones en radio se comparan con una imagen óptica de W28, y con la emisión en rayos X, observada con el satélite ROSAT. Este remanente muestra una clara morfología híbrida, tipo cáscara en frecuencias de radio y de centro lleno en las bandas óptica y de rayos X blandos.

  13. Case Study: del Amo Bioventing

    EPA Science Inventory

    The attached presentation discusses the fundamentals of bioventing in the vadose zone. The basics of bioventing are presented. The experience to date with the del Amo Superfund Site is presented as a case study.

  14. [I costi farmacologici della terapia di conversione con farmaci biologici nel carcinoma del colon-retto con metastasi epatiche].

    PubMed

    Giuliani, Jacopo; Bonetti, Andrea

    2016-08-01

    Riassunto. Lo scopo di questo studio è quello di valutare i costi dei farmaci (con particolare riferimento alle terapie con farmaci biologici) utilizzati nella terapia di conversione in una popolazione non selezionata di pazienti affetti da carcinoma del colon-retto in stadio avanzato, al fine di ottenere una resezione epatica R0. In questa rassegna sono stati selezionati i report completi e gli aggiornamenti di tutti gli studi clinici randomizzati (di fase II e fase III) che confrontassero almeno 2 regimi di terapia con farmaci biologici in prima linea in pazienti affetti da carcinoma del colon-retto in stadio avanzato di malattia. I costi dei farmaci sono stati ricavati dalla nostra Farmacia Ospedaliera e sono espressi in euro (€). Il nostro studio inizia con la valutazione di 683 abstract. 48 tria sono stati considerati adeguati per una successiva analisi. Una valutazione più approfondita ha portato all'esclusione di 37 trial, lasciando alla valutazione finale 11 studi clinici randomizzati (3 trial di fase II, per un totale di 522 pazienti, e 8 studi di fase III, per un totale di 7191 pazienti). I costi dei farmaci utilizzati nella terapia di conversione aumentano con la sostituzione del 5-fluorouracile con la capecitabina e, in misura maggiore, con l'introduzione degli agenti biologici. In questo lavoro sono presentati due punti chiave. Primo, i costi degli agenti farmacologici utilizzati nei regimi di prima linea a base di agenti biologici più comunemente utilizzati nel trattamento del carcinoma del colon-retto in stadio avanzato sono molto variabili. Secondo, i dati di efficacia dei regimi pubblicati, in termini di tassi di resezione, dipendono dalla selezione dei pazienti, dalle caratteristiche del tumore e dal tipo di schema di terapia. PMID:27571559

  15. IL TRAPIANTO ORTOTOPICO DEL FEGATO

    PubMed Central

    STARZL, THOMAS E.

    2010-01-01

    E’ormai noto che esiste la possibilità rivoluzionaria di utilizzare il fegato per il trattamento della stadio terminale delle epatopatie. Nel gennaio 1980 si celebra il decimo anna di sopravvivenza con fegato trapiantato (la più lunga della letteratura) di un paziente da noi trattato. Si tratta di uno dei 12 malati sottoposti a trapianto e seguiti per più di 5 anni. La nota positiva di questa tipo di trattamento è rappresentata dall’eccellente tenore di vita che i pazienti conducono e dalla riabilitazione sociale e professionale. La nota negativa è data, invece, dal fatto che i buoni risultati non vengono raggiunti con regolarità e non possono essere previsti con esattezza. In questa breve rassegna considereremo la esperienza da noi fatta presso l’Università di Denver nel Colorado, mettendo in risalto le cause dell’elevata mortalità precoce e le prospettive future di questa mezzo terapeutico. PMID:21572898

  16. DelPhi: a comprehensive suite for DelPhi software and associated resources

    PubMed Central

    2012-01-01

    Background Accurate modeling of electrostatic potential and corresponding energies becomes increasingly important for understanding properties of biological macromolecules and their complexes. However, this is not an easy task due to the irregular shape of biological entities and the presence of water and mobile ions. Results Here we report a comprehensive suite for the well-known Poisson-Boltzmann solver, DelPhi, enriched with additional features to facilitate DelPhi usage. The suite allows for easy download of both DelPhi executable files and source code along with a makefile for local installations. The users can obtain the DelPhi manual and parameter files required for the corresponding investigation. Non-experienced researchers can download examples containing all necessary data to carry out DelPhi runs on a set of selected examples illustrating various DelPhi features and demonstrating DelPhi’s accuracy against analytical solutions. Conclusions DelPhi suite offers not only the DelPhi executable and sources files, examples and parameter files, but also provides links to third party developed resources either utilizing DelPhi or providing plugins for DelPhi. In addition, the users and developers are offered a forum to share ideas, resolve issues, report bugs and seek help with respect to the DelPhi package. The resource is available free of charge for academic users from URL: http://compbio.clemson.edu/DelPhi.php. PMID:22583952

  17. Tierra del Fuego, Argentina, South America

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The Mitre Peninsula is the easternmost tip of Tierra del Fuego, Argentina, (54.5S, 65.5W). Early winter snow can be seen on this south tip of the Andes Mountains. These same mountains continue underwater to Antarctica. The Strait of Magellan, separating the South American mainland from Tierra del Fuego is off the scene to the north and west, but the Strait of LeMaire, separating Tierra del Fuego from the Isla de los Estados can be seen.

  18. [Textual Research on Wang Fengchun's Life].

    PubMed

    Wang, Ti

    2012-01-01

    WANG Fengchun (1884 - 1949), born in Wu County, Jiangsu Province, was one of the four famous doctors of Beijing in the Republic of China periods. He learned Confucianism during his childhood and then learned medicine from AI Buchan, a famous doctor in Wuzhong area. In 1908, he went to Beijing and was appointed as the prosecutor of the court of law and a medical official, but also had learnt medicine from LI Jun, the head of the Business Ministry. In 1910, Wang resigned and lived as doctor in Beijing. According to the literature, from 1935 to 1942, Wang had been appointed 11 times as a member of Beiping (Beijing) TCM examination committee or test committee. In 1938, he was appointed as president of the Beijing Branch of the National Medical Professional Association and created the Beijing Medicine Monthly in 1939. In September 1939, Wang began to make preparations for a TCM symposium, i.e. the Medicine Symposium which was established officially in October 1939. In 1941, he was appointed as the director of the Beijing Traditional Chinese Medicines Workshop, employing famous doctors to cultivate reserve talents of medicines. Being a realist, he often exchanged opinions with TCM and western medical doctors and also made a contribution to medical education. PMID:22613482

  19. [Textual research for Tibetan medicine Qumazi].

    PubMed

    Luo, Wu-zheng; Li, Qi-en; Chen, Jing; Dor, Jerenchen; Tao, Si-yu; Shi Jin-bo; Xu, Ying-zhou; Yan, Xing-li

    2015-05-01

    Qumazi is a commonly used Tibetan medicine. With a long history, it can be found in the Four Medical Tantras written by gYu-thog rNying-ma Yon-tan mGon-po since the 8th century AD. Qumazi grows in mudflats and fields, including species growing in highlands, lowlands, mountains and farmlands. According to records in Crystal Beads Materia Medica, it features green sword-shaped leaves, thin stems with red veins, inserted panicles, white chicken-like flowers and copper needle row-like roots. However, there are many inconsistent morphological descriptions for Qumazi plants in many Chinese versions of Tibetan medicine books. In this article, after studying ancient and modern Tibetan medicine books, consulting experts and conducting surveys, the authors confirmed that Qumazi belongs to Rheum of Polygonaceae, including Rheum nobile Hook. f. et. Thoms, R. globulosum Gage, R. alexandrae Hook. f. et. Thoms, R. pumilum Maxim and R. delavayi Franch. In some regions, Qumazi is substituted by R. spiciforme Royle and R. przewalskyi Losinsk. After the Chinese version of Qinghai-Tibet Plateau Drug Illustrations was published in 1972, Qumazi has been miswritten as P. sibiricum Laxm in many Chinese versions of Tibetan medicine books, perhaps because P. sibiricum Laxm has many similar features with Qumazi as described in Crystal Beads Materia Medica and then is mistranslated from Tibetan to Chinese versions. According to records, Qumazi can reduce edema and is mainly applied to treat the minamata disease in clinic. PMID:26390671

  20. Distribute The Highest Selected Textual Recommendation (DTHSTR)

    Energy Science and Technology Software Center (ESTSC)

    2012-05-01

    The DTHSTR computer code uses a set of documents as seed documents to recommend documents of interest from a large, target set of documents. The computer code provides results that show the highest recommended documents as well as the terms in common between the recommend document and the corresponding seed document that is most similar.

  1. Accessing textual information embedded in Internet images

    NASA Astrophysics Data System (ADS)

    Antonacopoulos, Apostolos; Karatzas, Dimosthenis; Ortiz-Lopez, Jordi

    2000-12-01

    Indexing and searching for WWW pages is relying on analyzing text. Current technology cannot process the text embedded in images on WWW pages. This paper argues that this is a significant problem as text in image form is usually semantically important (e.g. headers, titles). The results of a recent study are presented to show that the majority (76%) of words embedded in images do not appear elsewhere in the main text and that the majority (56%) of ALT tag descriptions of images are incorrect of do not exist at all. Research under way to devise tools to extracted text from images based on the way humans perceive color differences is outlined and results are presented.

  2. EVA - A Textual Data Processing Tool.

    ERIC Educational Resources Information Center

    Jakopin, Primoz

    EVA, a text processing tool designed to be self-contained and useful for a variety of languages, is described briefly, and its extensive coded character set is illustrated. Features, specifications, and database functions are noted. Its application in development of a Slovenian literary dictionary is also described. (MSE)

  3. Automatic Generation of Synonyms Using Textual Data

    NASA Astrophysics Data System (ADS)

    Kasahara, Kaname; Inago, Nozomu; Kato, Tsuneaki

    A method of generating synonyms for a stimulus word using a computer is proposed. Vector Space Model, where words in text data are arranged in a multi-dimensional space and degree of similarity between two words of them is calculated from how close the words are in the space, may be available to the method. However, it is not easy to optimize parameters in the method because there is no appropriate standard synonym database where proper synonyms for a stimulus word are thoroughly collected. Therefore, we first built such a standard database employing two steps of human subjects expriments, and optimized the parameters of the method of generating synonyms. As the result, it was found that the Vector Space Model-based method using an electronic dictionary as source is better to generate synonyms than the one using a text corpus and an ordinal method using a thesaurus.

  4. Performing Literature in an Age of Textuality.

    ERIC Educational Resources Information Center

    Bowman, Michael S.

    1996-01-01

    Discusses issues of interpretation versus reading in oral interpretation, or the performance of literature. Offers an extended classroom example to make the case for alternative kinds of performance and their ability to keep practices of performing literature valuable in the current academic scene. (SR)

  5. Líneas Vitales: Programas y servicios del NCI

    Cancer.gov

    Artículos y videos sobre los programas y servicios del Instituto Nacional del Cáncer de la serie educativa Líneas Vitales del NCI, la cual está dirigida especialmente a poblaciones multiculturales.

  6. Control del cáncer y salud mundial: noticia del Instituto Nacional del Cáncer (NCI)

    Cancer.gov

    En combinación con una reunión de alto nivel de las Naciones Unidas sobre enfermedades no transmisibles en países en vías de desarrollo, el doctor Harold Varmus, director del NCI, y el doctor Ted L. Trimble, del NCI, han publicado un comentario en Science

  7. Descripción del coronógrafo a ser instalado en Argentina (MICA)

    NASA Astrophysics Data System (ADS)

    Stenborg, G.; Francile, C.; Schwenn, R.; Epple, A.; Rovira, M.

    El ``Coronógrafo de espejo para Argentina'' es un telescopio solar terrestre a ser colocado en el Observatorio Astronómico Félix Aguilar (El Leoncito), antes de finalizar 1996, como parte de un programa de ciencia bilateral entre Alemania y Argentina. Eclipses fotográficos de alta resolución han revelado que la corona solar es altamente estructurada y variable. De hecho, está contínuamente deformada y moldeada por los movimientos convectivos de los extremos de los arcos magnéticos en la fotosfera, estando, en muchas oportunidades, afectada por explosivas liberaciones de energía. MICA, en conjunción con otros telescopios solares espaciales y terrestres, tratará de contribuir al entendimiento de cuestiones fundamentales de la física solar. Entre ellas: cómo la corona está siendo calentada, dónde y cómo el viento solar es acelerado, qué causa los transitorios coronales, etc. Para ello investigará la distribución de los parámetros del plasma y su evolución con el tiempo, la estructura espacial de la corona en fina y gran escala, procesos que ocurren en los transitorios coronales y factores que los disparan, etc. Para responder a estas cuestiones MICA observará la atmósfera solar por sobre el limbo entre 1.1 y 2 radios solares aproximadamente, usando un nuevo tipo de sistema coronográfico que permite suprimir el brillo del disco solar suficientemente bien, tomando las imágenes con una cámara CCD de 1024x1024 pixels, codificada en 12 bits, pudiendo el mismo ser operado en forma remota. En la presente exposición describiremos las características del instrumento, cómo será controlado y qué esperamos observar basados en las imágenes obtenidas por los telescopios de similares características LASCO C1 a bordo del SOHO y PICO (ubicado en el Observatorio de Pic du Midi, Francia).

  8. Produccion Gaseosa del Cometa Halley: Erupciones Y Fotodisociacion del Radical OH

    NASA Astrophysics Data System (ADS)

    Silva, A. M.; Mirabel, I. F.

    1990-11-01

    RESUMEN:En este trabajo informamos la detecci6n de 20 erupciones en la li'nea de =18cm (1667MHz) del radical OH en el Cometa Halley.Las observaciones incluyen todos los monitoreos existentes y se extienden desde 120 dias antes del perihelio hasta 90 dias despues.Se detectan bruscos crecimientos en el flujo medido,hasta un factor 1O,seguidos por decaimientos lentos asociados con la fotodisociaci6n del OH. Se obtuvieron valores para el tiempo de vida fotoquimico del OH y del H2O basandose en el modelo desarrollado previamente por Silva(1988). Esos tiempos de vida estan de acuerdo con predicciones teoricas y con las observaciones en el Ultravioleta, y los resultados, los que son fuertemente dependientes de la velocidad heliocentrica del Coineta (variando hasta un factor 6), han sido calculados para varios rangos de velocidad entre +28 y -28 km/seg. Key wo'L :

  9. Análise Temporal de Estruturas Morfológicas na Cauda do Tipo I do Cometa P/Halley

    NASA Astrophysics Data System (ADS)

    Voelzke, M. R.; Matsuura, O. T.

    1996-08-01

    Com base em (Brandt et al, 1992), centenas de imagens do cometa P/Halley foram visualmente analisadas, objetivando examinar possíveis perturbações magnetohidrodinâmicas ao longo da cauda do tipo I. Do total de 1439 imagens, abrangendo o período entre 16 de outubro de 1982 e 12 de fevereiro de 1991, foram escolhidas 531 do período entre 17 de setembro de 1985 e 06 de julho de 1986 por mostrarem cauda bem desenvolvida e rica de estruturas morfológicas. Nelas constatou-se a existência de 124 estruturas ondulatórias (trens de onda) ao longo da cauda principal, 27 ao longo de caudas secundárias, 109 ondas solitárias (sólitons) ao longo da cauda principal, 36 ao longo de caudas secundárias, 12 caudas do tipo Swan, 47 eventos de desconexão e 23 regiões de adensamento ("knots"). Foi examinada a correlação temporal entre esses diferentes tipos de eventos. Os de desconexão foram analisados isoladamente. Seus movimentos próprios foram calculados, bem como os seus instantes iniciais, o que nos permitiu inferir a passagem do cometa pela fronteira entre setores magnéticos distintos. A velocidade do plasma cometário desconectado foi corrigida dos efeitos de projeção e correlacionada com a distância heliocêntrica do cometa. Também foi investigada a periodicidade de ocorrência das desconexães, e constatado que sua distribuição é bimodal. Por fim, a possibilidade dos modos de propagação de ondas MHD "sausage" e "kink" superficiais ou volumétricas, é discutida no contexto das descontinuidades magnéticas tangenciais. - Brandt, J.C., Niedner Jr., M.B., Rahe, J.: The International Halley Watch Atlas of Large-Scale Phenomena. Impresso por: Johnson Printing Co, Boulder, CO. University of Colorado-Boulder, 1992.

  10. Gonadal dysgenesis in del (18p) syndrome

    SciTech Connect

    Telvi, L.; Ion, A.; Fouquet, F.

    1995-07-17

    We report on a girl with syndromal gonadal dysgenesis and a de novo del (18p). Genetic factors controlling gonadal development are located not only on the X chromosome, but also on autosomes. The present case suggests that one of these genes is situated on 18p. We conclude that patients with del (18p) syndrome should be evaluated for gonadal dysgenesis. 16 refs., 3 figs.

  11. "Processing Instruction": un tipo di grammatica comunicativa per la classe di lingua straniera. Il caso del futuro italiano. (Processing Instruction: One Type of Communicative Grammar for the Foreign Language Classroom. The Case of the Italian Future Tense).

    ERIC Educational Resources Information Center

    Benati, Alessandro

    2000-01-01

    Examines the theoretical and practical rationale for processing instruction as a method of incorporating grammar instruction in a communicative foreign language approach. Presents results of a study on the role of processing instruction on the learning of the Italian future indicative tense by a group of English-speaking students. Results…

  12. Intertextual Sexual Politics: Illness and Desire in Enrique Gomez Carrillo's "Del amor", "del dolor y del vicio" and Aurora Caceres's "La rosa muerta"

    ERIC Educational Resources Information Center

    LaGreca, Nancy

    2012-01-01

    This study explores the intertextuality between Aurora Caceres's "La rosa muerta" (1914) and the novel "Del amor, del dolor y del vicio" (1898) by her ex-husband, Enrique Gomez Carrillo. Caceres strategically mentions Gomez Carrillo's novel in "La rosa muerta" to invite a reading of her work in dialogue with his. Both narratives follow the sexual…

  13. Composição química, evolução e cinemática de estrelas de tipo solar

    NASA Astrophysics Data System (ADS)

    Silva, R. O.; Porto de Mello, G. F.; Milone, A. C.

    2003-08-01

    A composição química das estrelas de tipo solar é um diagnóstico extremamente valioso da evolução química do disco da Galáxia. Existe alguma evidência de que tal evolução tem sido heterogênea no espaço e ao longo do tempo e que a composição química do Sol pode não ser um padrão representativo de abundâncias. Neste trabalho, foram obtidas as abundâncias dos elementos químicos C, N, Na, Mg, Si, Ca, Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Sr, Y, Zr, Ba, La, Ce, Nd e Sm em uma amostra de estrelas de tipo solar na vizinhança solar (distâncias £ 25 pc). A técnica empregada foi a análise espectroscópica diferencial em relação ao Sol, baseando-se em dados de alta resolução (R ~ 46.000) e alta razão sinal/ruído (S/R > 300), obtidos com o espectrógrafo échelle de bancada do telescópio de 1,5 m do CTIO. Adicionalmente, abundâncias de C e N foram obtidas através de síntese de bandas moleculares dos Sistemas Eletrônicos Swan do C2 e Vermelho do CN utilizando-se um programa de síntese espectral. Os parâmetros atmosféricos foram estabelecidos usando cores fotométricas, o equilíbrio de excitação e ionização de linhas do Fe e a análise da temperatura e da luminosidade estelares no diagrama HR. Os resultados de abundâncias químicas obtidos proporcionam uma melhor compreensão da relação das abundâncias conhecidas para o Sol com a das estrelas anãs de tipo G da população local, uma vez que as razões de abundâncias de diversos elementos (em relação ao ferro) obtidas para estrelas de metalicidade semelhante à solar diferem daquelas obtidas para o Sol. Tais resultados também contribuem para um melhor entendimento do processo de evolução química da vizinhança solar e do enriquecimento nucleossintético do disco galáctico.

  14. Radio-Observaciones del OH EN la Coma del Cometa Halley Desde EL Hemisferio Sur

    NASA Astrophysics Data System (ADS)

    Silva, A. M.; Bajaja, E.; Morras, R.; Cersosimo, J. C.; Martin, M. C.; Arnal, E. M.; Poppel, W. G. L.; Colomb, F. R.; Mazzaro, J.; Olalde, J. C.; Boriakoff, V.; Mirabel, I. F.

    1987-05-01

    Se utilizó una antena de 30 metros del Instituto Argentino de Radioastronomía para observaciones diarias Cf ebrero a abril de 1986) de la transición en 1667 MHz ( λ = 18 cm) del OH en la coma del cometa Halley. De las observaciones realizadas se concluye: 1) El número promedio de moléculas de OH en la coma durante 37 días de observación fue de (8.9±3.5)x1034 moléculas, lo que implica una tasa de producción promedio de OH de 1.8x1029 moléculas seg-1 y consecuentemente una pérdida de masa promedio de 17±6 toneladas seg-1 . Este valor está de acuerdo con las mediciones realizadas por las sondas Vega y Giotto. 2) El monitoreo desde el lAR revela la existencia de variaciones bruscas en los flujos de absorción del OH. Estas variaciones son consistentes con los modelos que representan la producción gaseosa a partir de ejecciones y/o desprendimientos discretos de materia congelada del núcleo. 3) Las variaciones en la densidad de flujo son consistentes con las estimaciones de los tiem- pos de vida medios del H2O y del OH en presencia del campo de radiación solar. 4) Se encuentra una correlación entre la intensidad del flujo absorbido y anisotropías en Ia dinamica de la coma.

  15. Calidad de Imagen del Telescopio UNAM212

    NASA Astrophysics Data System (ADS)

    Cobos, F. J.; Teiada de Vargas, C.

    1987-05-01

    El telescopio UNAM2l2, del Observatorio Astronómico Nacional, situado en la Sierra de San Pedro Mártir (Baja California, México), cumplira en un futuro muy cercano siete años de uso para fines de investigación astronómica. Aunque en este tiempo no se ha efectuado un estudio sistemático acerca de su comportamiento óptico y de los factores que influyen en la calidad de las imágenes, se han realizado pruebas diversas, estudios parciales y reuniones especificas, cuyos resultados no siempre se han difundido ampliamente y generalmente no se han presentado por escrito. Es por ello que hemos creido necesario intentar una recopilación de la información existente para poder con ella establecer un diagnóstjco que, aunque no sea definitivo, sirva de base para futuros trabajos tendientes a optimizar el comportamiento óptico del telescopio. Es evidente que un buen número de las conclusiones que se presentan son resultado del trabajo de muchas personas ó de esfuerzos colectivos. Asimismo, hemos tratado de localizar información bibliográfica que pueda ser de utilidad. Nuestro objetivo primordial ha consistido en centrarnos en la óptica del telescopio y su calidad, pero también se han considerado otros aspectos que puedan afectar las imágenes obtenidas tales como: celda del primario, `seeing' local y externo, flexiones posibles en la estructura mecánica del telescopio, etc.

  16. Visiting the Gödel universe.

    PubMed

    Grave, Frank; Buser, Michael

    2008-01-01

    Visualization of general relativity illustrates aspects of Einstein's insights into the curved nature of space and time to the expert as well as the layperson. One of the most interesting models which came up with Einstein's theory was developed by Kurt Gödel in 1949. The Gödel universe is a valid solution of Einstein's field equations, making it a possible physical description of our universe. It offers remarkable features like the existence of an optical horizon beyond which time travel is possible. Although we know that our universe is not a Gödel universe, it is interesting to visualize physical aspects of a world model resulting from a theory which is highly confirmed in scientific history. Standard techniques to adopt an egocentric point of view in a relativistic world model have shortcomings with respect to the time needed to render an image as well as difficulties in applying a direct illumination model. In this paper we want to face both issues to reduce the gap between common visualization standards and relativistic visualization. We will introduce two techniques to speed up recalculation of images by means of preprocessing and lookup tables and to increase image quality through a special optimization applicable to the Gödel universe. The first technique allows the physicist to understand the different effects of general relativity faster and better by generating images from existing datasets interactively. By using the intrinsic symmetries of Gödel's spacetime which are expressed by the Killing vector field, we are able to reduce the necessary calculations to simple cases using the second technique. This even makes it feasible to account for a direct illumination model during the rendering process. Although the presented methods are applied to Gödel's universe, they can also be extended to other manifolds, for example light propagation in moving dielectric media. Therefore, other areas of research can benefit from these generic improvements. PMID

  17. Vigilando la Calidad del Agua de los Grandes Rios de la Nacion: El Programa NASQAN del Rio Grande (Rio Bravo del Norte)

    USGS Publications Warehouse

    Lurry, Dee L.; Reutter, David C.; Wells, Frank C.; Rivera, M.C., (translator); Munoz, A.

    1998-01-01

    La Oficina del Estudio Geologico de los Estados Unidos (U.S. Geological Survey, 0 USGS) ha monitoreado la calidad del agua de la cuenca del Rio Grande (Rio Bravo del Norte) desde 1995 como parte de la rediseiiada Red Nacional para Contabilizar la Calidad del Agua de los Rios (National Stream Quality Accounting Network, o NASOAN) (Hooper and others, 1997). EI programa NASOAN fue diseiiado para caracterizar las concentraciones y el transporte de sedimento y constituyentes quimicos seleccionados, encontrados en los grandes rios de los Estados Unidos - incluyendo el Misisipi, el Colorado y el Columbia, ademas del Rio Grande. En estas cuatro cuencas, el USGS opera actualmente (1998) una red de 40 puntos de muestreo pertenecientes a NASOAN, con un enfasis en cuantificar el flujo en masa (la cantidad de material que pasa por la estacion, expresado en toneladas por dial para cada constituyente. Aplicacando un enfoque consistente, basado en la cuantificacion de flujos en la cuenca del Rio Grande, el programa NASOAN esta generando la informacion necesaria para identificar fuentes regionales de diversos contaminantes, incluyendo sustancias qui micas agricolas y trazas elementos en la cuenca. EI efecto de las grandes reservas en el Rio Grande se puede observar segun los flujos de constituyentes discurren a 10 largo del rio. EI analisis de los flujos de constituyentes a escala de la cuenca proveera los medios para evaluar la influencia de la actividad humana sobre las condiciones de calidad del agua del Rio Grande.

  18. Educational and Demographic Profile: Del Norte County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Del Norte County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  19. Del Mod System. 1972 Annual Report.

    ERIC Educational Resources Information Center

    Purnell, Charlotte H.

    The overall aim of the Del Mod System is the improvement of science programs taught in Delaware schools; it is a working agreement among the University of Delaware, Delaware Technical and Community College, Delaware State College, State Department of Public Instruction, industry, and the schools. It was formed to bring about changes in science…

  20. Andrea del Sarto rehabilitated: a psychoanalytic emendation.

    PubMed

    Trosman, Harry

    2002-01-01

    Ernest Jones's "The Influence of Andrea del Sarto's Wife on His Art" (1913) is an early example of psychoanalysis applied to the study of a prominent painter. Greatly influenced by Freud's Leonardo da Vinci and a Memory of His Childhood, Jones gave excessive credence to Vasari's highly prejudicial account of the life of del Sarto, on which the study relied heavily. Jones attempted to account psychologically for the circumstance that del Sarto, though highly skilled and "faultless," was not the equal of the three preeminent masters of the Italian High Renaissance: Leonardo, Michelangelo, and Raphael. Jones's uncritical acceptance of the Vasari biography encouraged him to view Sarto's assumed deficiency as the result of excessive attachment to his wife, a pathological uxoriousness. A contemporary psychoanalytic perspective, with its emphasis on the emotive response of the analyst, requires us to pay attention to the evocative nature of the work of the artist, an approach Jones neglected. In an examination of several paintings, the artist's sensitivity to the position of the spectator is explored, as is the interest in involving the viewer spatially and emotionally. An appreciation for the viewer's position is consistent with a capacity for using projected internal objects for creative purposes. The presence of this capacity suggests a revised view of del Sarto's contribution to art and of his relationship with his wife. PMID:12580329

  1. Clinical and laboratory update on the DEL variant.

    PubMed

    Nuchnoi, Pornlada; Thongbus, Jairak; Srisarin, Apapan; Kerdpin, Usanee; Prachayasittikul, Virapong

    2014-01-01

    Serological assays for the RhD blood group are based on detection of the RhD antigen on human red blood cells using a specific anti-D antibody. The weak expression of the RhD antigen in the DEL variant hinders the sensitivity of conventional serological assays. Evidence of anti-D immunization in patients with D-negativity who have received DEL-variant blood units has been reported in various populations. This observation has prompted the need for genetic epidemiological and clinical data on the DEL variant in the development of DEL molecular diagnostic testing. This review highlights the molecular features of the DEL variant, the clinical consequences of DEL-blood transfusion, and current approaches for detection of the DEL-variant for donor screening and transfusion. PMID:25316658

  2. Del Norte means north to recycling

    SciTech Connect

    Aquino, J.T.

    1998-06-01

    Del Norte Regional Recycling and Transfer Station is owned by the city of Oxnard, California and operated by BLT Enterprises, Inc. The Del Norte facility--located in southwestern Ventura County about an hour northwest of Los Angeles--processes polyethylene terephthalate (PET) and high-density polyethylene (HDPE) plastic containers, aluminum, steel, glass, old corrugated containers (OCC), newspapers, computer printout paper, white and colored ledger paper, coated book, supermix paper, telephone books, and old magazines. According to the company, there has been virtually no community opposition to the site. The facility has few neighbors, and those are agricultural. To keep the community relationship strong, the facility`s design and location all but eliminated odor and noise complaints. The building was designed against the prevailing wind pattern, and BLT processes odorous material fast. A misting system installed for dust suppression also can be used with a solution for odor control should the need arise.

  3. del, Einstein, Mach, Gamow, and Lanczos: Gödel's remarkable excursion into cosmology

    NASA Astrophysics Data System (ADS)

    Rindler, Wolfgang

    2009-06-01

    This article is an expanded version of a talk given at the International Symposium Celebrating the 100th Birthday of Kurt Gödel (Vienna, 2006). It seeks to trace the path which led this preeminent mathematical logician to discover one of the famous results of General Relativity, the rotating Gödel Universe. This universe has some remarkable properties, which gave the philosophers plenty to worry about. It allows a person to travel into his own past, with all the ensuing causal paradoxes; it allows no unique temporal ordering of events; and though Gödel's Universe is rigid and infinite, the Foucault pendulum planes everywhere in it rotate in unison, a clear affront to adherents of Mach's Principle. We also discuss some lesser known precursors in the field, who just missed discovering Gödel's universe. While the article gives all the necessary derivations in simplified form (for example, of the metric and its geodesics), much of it should be accessible to the general reader, who can simply skip most of the mathematics. [Reprinted, with permission, from Kurt Gödel and the Foundations of Mathematics: Horizons of Truth, edited by Matthias Baaz, Christos H. Papadimitriou, Dana S. Scott, Hilary Putnam, and Charles L. Harper, Jr. (Cambridge U. P., New York, 2009).

  4. Procesamiento Digital de Imagenes del Cometa Halley

    NASA Astrophysics Data System (ADS)

    Ferrin, L.; Fuenmayor, F.; Naranjo, O.; Bulka, P.; Mendoza, C.

    1987-05-01

    Se reportan observaciones fotográficas del cometa Halley, obtenidas con los telescopios Schmidt de 1-m del CIDA, y de 35 cms de la ULA. Se hicieron exposiciones desde 2 segundos a 30 minutos y se utilizaron emulsiones IIa-O, 103a-F, y 103a-D, guladas manualmente 0 automaticámente. Las imágenes fueron digitalizadas con el microdensitómetro PDS, y procesadas con el sistema HACIENDA del CCIBM. Se experimentó con la Transformada de Fourier en dos dimensiones, y con la aplicación de filtros de paso alto y bajo. Se encontró que el metodo de "autocorrelación" es el mejor para separar "la vegetación" de "la montaña". Se aplicaron diversas técnicas a fin de cubrir ambos extremos: a) enfatizar detalles débiles en la cola, y b) penetrar en las regiones más intensas de la coma. Se lograron ambos objetivos. Detalles en la cola permitieron determinar velocidades de propagación de unos 50 a 90 kms/ seg. Se pudieron detectar no menos de tres perturbaciones en "Y", y una en 5? Co de Cisne). Se cree que las primeras están asociadas a eventos de desconexión. Se puede separar la cola de gas de la de polvo. Las fotos de color permiten enfatizar diferentes regiones espectrales con mayor claridad aún. El "balance" del color puede ser hecho con la computadora.

  5. Visualization of the Gödel universe

    NASA Astrophysics Data System (ADS)

    Buser, M.; Kajari, E.; Schleich, W. P.

    2013-01-01

    The standard model of modern cosmology, which is based on the Friedmann-Lemaître-Robertson-Walker metric, allows the definition of an absolute time. However, there exist (cosmological) models consistent with the theory of general relativity for which such a definition cannot be given since they offer the possibility for time travel. The simplest of these models is the cosmological solution discovered by Kurt Gödel, which describes a homogeneous, rotating universe. Disregarding the paradoxes that come along with the abolishment of causality in such space-times, we are interested in the purely academic question of how an observer would visually perceive the time travel of an object in Gödel's universe. For this purpose, we employ the technique of ray tracing, a standard tool in computer graphics, and visualize various scenarios to bring out the optical effects experienced by an observer located in this universe. In this way, we provide a new perspective on the space-time structure of Gödel's model.

  6. Morphology, geology and geochemistry of the "Salar del Gran Bajo del Gualicho" (Rio Negro, Argentina)

    USGS Publications Warehouse

    Angelucci, A.; Barbieri, M.; Brodtkorb, A.; Ciccacci, S.; Civitelli, G.; De Barrio, R.; Di, Filippo M.; Fredi, P.; Friedman, I.; Lombardi, S.; Schalamuk, A.I.; Toro, B.

    1996-01-01

    A multidisciplinary study of the Gran Bajo del Gualicho area (Rio Negro - Argentina) was carried out; the aim was to delineate its geological and geomorphological evolution and to estabilish the genesis of salts filling the depression. Climatic conditions were analized first to individuate their role in the present morphogenetic processes; moreover the main morphological features of present landscape were examined as well as the stratigraphy of the outcropping formations, and of the Gran Bajo del Gualicho Formation in particular. Finally, a possible geomorphological evolution of the studied area was traced. Geophysical analyses allowed to estabilish that the paleosurface shaped on the crystalline basement is strongly uneven and shows evidence of the strong tectonic phases it underwent. The result of isotope analyses confirmed that the salt deposits on the Gran Bajo del Gualicho bottom were produced by fresh water evaporation, while strontium isotope ratio suggested that such waters were responsible for solubilization of more ancient evaporitic deposits.

  7. A Description of Del Mod and Its Final Evaluation, Final Report, Volume I.

    ERIC Educational Resources Information Center

    Purnell, Charlotte H.; Bolig, John R.

    This monograph presents an overview of five Del Mod System final reports, comments by the project director, financial structure of the Del Mod System, and descriptions of Del Mod Projects. The Del Mod System was concerned with changing the science and mathematics education programs in the state of Delaware. Between 1970 and 1976, Del Mod conducted…

  8. Huave de San Mateo del Mar, Oaxaca (Huave of San Mateo del Mar, Oaxaca).

    ERIC Educational Resources Information Center

    Mexico Coll. (Mexico City)

    This document is one of 17 volumes on indigenous Mexican languages and is the result of a project undertaken by the Archivo de Lenguas Indigenas de Mexico. This volume contains information on Huave, an indigenous language of Mexico spoken in San Mateo del Mar, in the state of Oaxaca. The objective of collecting such a representative sampling of…

  9. Pastoral del Nino: Bringing the Abundant Life to Paraguayan Children

    ERIC Educational Resources Information Center

    Austin, Ann Berghout; Aquino, Cyle; Burro, Elizabeth

    2007-01-01

    Pastoral del Nino is transforming children's lives in rural Paraguay. Part of Pastoral Social (Catholic Social Services), Pastoral del Nino's primary focus is to bring "vida en abundancia" (the abundant life) to families by ensuring that mothers survive childbirth and children reach their first birthdays. In addition, the organization promotes…

  10. 75 FR 11104 - Del Norte Resource Advisory Committee (RAC)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... Forest Service Del Norte Resource Advisory Committee (RAC) AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Del Norte Resource Advisory Committee (RAC) will meet in Crescent City... and Designated Federal Official roles and (5) review operational guidelines; (6) selection of...

  11. Research and Evaluation Within the Del Mod System.

    ERIC Educational Resources Information Center

    Bolig, John R.

    Described is the Del Mod System, its inception, the fundings associated with it, and its objectives. A number of projects have already been completed and implemented. This monograph describes the evaluations of such projects and of the Del Mod systems-approach to science education. The area of evaluation and the method of data collection (with…

  12. 33 CFR 80.1118 - Marina Del Rey, CA.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Marina Del Rey, CA. 80.1118 Section 80.1118 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Coast § 80.1118 Marina Del Rey, CA. (a) A line drawn...

  13. A new iterative Chebyshev spectral method for solving the elliptic equation [del] [center dot] ([sigma] [del]u) = f

    SciTech Connect

    Zhao, Shengkai; Yedlin, M.J. )

    1994-08-01

    We present a new iterative Chebyshev spectral method for solving the elliptic equation [del] [center dot] ([sigma] [del]u) = f. We rewrite the equation in the form of a Poisson's equation [del][sup 2]u = (f - [del]u [center dot] [del][sigma]/[sigma]). In each iteration we compute the right-hand side terms from the guess values first. Then we solve the resultant Poisson equation by a direct method to obtain the updated values. Three numerical examples are presented. For the sam number of iterations, the accuracy of the present method is about 6-8 orders better than the Chebyshev spectral multigrid method. On a SPARC Station 2 computer, the CPU time of the new method is about one-third of the Chebyshev spectral multigrid method. To obtain the same accuracy, the CPU time of the present method is about one-tenth of the Chebyshev spectral multigrid method. 17 refs., 5 figs., 3 tabs.

  14. Estudio teórico del CO2. Orbitales de valencia y del ``core''

    NASA Astrophysics Data System (ADS)

    Olalla Gutiérrez, E.

    Hemos calculado las intensidades de las transiciones E1 a los miembros de las series de Rydberg con origen en los orbitales ``no enlazantes'' del dióxido de carbono, especie de conocida relevancia atmosférica. Se han computado, asimismo, los continuos de fotoionización correspondientes a los distintos canales de ionización, representándolos como densidad espectral de fuerza de oscilador frente a la energía del fotón incidente; mostramos los resultados df/dE para la fotoionización total de esta especie en el intervalo 15-60 eV. Todos los cálculos se han llevado a cabo mediante la formulación Molecular del Método de los Orbitales de Defecto Cuántico, MQDO [1,2]. La calidad de los resultados que presentamos se ha evaluado en base a la comparación con los datos, tanto experimentales como teóricos, disponibles en la bibliografía. El acuerdo encontrado es altamente satisfactorio

  15. Neurological aspects of del(1q) syndrome.

    PubMed

    Murayama, K; Greenwood, R S; Rao, K W; Aylsworth, A S

    1991-09-15

    We have studied three children with de novo terminal deletion of the long arm of chromosome 1 (46,XX,del(1)(q43)). They all have minor anomalies and neurological signs (severe psychomotor developmental delay, generalized hypotonia, and seizures) that have been described previously. In addition, all of these three patients have autistic-like behavior. They avoid eye contact, show no interest in people, express little emotion, and repeat stereotypic movements such as head nodding and purposeless finger manipulation. They also spend excessive time in making unusual sounds consisting of a high-pitched shrill cry with little intonation in infancy and a harsh, strained, and glottal stridency in later life. They make no labial, lingual, or nasal sounds. We suggest that these observations may be unique clinical manifestations of certain terminal 1q deletions. PMID:1746617

  16. Illuminating water and life: Emilio Del Giudice.

    PubMed

    Ho, Mae-Wan

    2015-01-01

    The quantum electrodynamics theory of water put forward by Del Giudice and colleagues provides a useful foundation for a new science of water for life. The interaction of light with liquid water generates quantum coherent domains in which the water molecules oscillate between the ground state and an excited state close to the ionizing potential of water. This produces a plasma of almost free electrons favoring redox reactions, the basis of energy metabolism in living organisms. Coherent domains stabilized by surfaces, such as membranes and macromolecules, provide the excited interfacial water that enables photosynthesis to take place, on which most of life on Earth depends. Excited water is the source of superconducting protons for rapid intercommunication within the body. Coherent domains can also trap electromagnetic frequencies from the environment to orchestrate and activate specific biochemical reactions through resonance, a mechanism for the most precise regulation of gene function. PMID:26098522

  17. Wave maps from Gödel's universe

    NASA Astrophysics Data System (ADS)

    Barletta, Elisabetta; Dragomir, Sorin; Magliaro, Marco

    2014-10-01

    Using a result by Koch (1988 Trans. Am. Math. Soc. 307 827-41) we realize Gödel's universe G_{α }^{4}=({{{R}}^{4}},{{g}_{α}}) as the total space of a principal {R}-bundle over a strictly pseudo-convex CR manifold M3 and exploit the analogy between {{g}_{Yalpha;}} and Fefferman's metric {{F}_{θ}} (Fefferman 1976 Ann. Math. 103 395-416 104 393-4) to show that for any {R}-invariant wave map Φ of G_{α}^{4} into a Riemannian manifold N, the corresponding base map φ :{{M}^{3}}\\to N is subelliptic harmonic, with respect to a canonical choice of contact form θ on M3. We show that the subelliptic Jacobi operator J_{b}^{φ} of ϕ has a discrete Dirichlet spectrum on any bounded domain D\\subset {{M}^{3}} supporting the Poincaré inequality on \\mathop{W}\\limits^{\\circ }{}_{H}^{1,2}(D,{{φ}^{-1}}TN) and Kondrakov compactness, i.e. compactness of the embedding \\mathop{W}\\limits^{\\circ }{}_{H}^{1,2}(D,{{φ }^{-1}}TN)\\hookrightarrow {{L}^{2}}(D,{{φ}^{-1}}TN). We exhibit an explicit solution π :G_{α}^{4}\\to {{M}^{3}} to the wave map system on G_{α}^{4}, of index in{{d}^{Ω}}(π)\\geqslant 1 for any bounded domain Ω \\subset G_{α}^{4}. Mounoud's distance (Mounoud 2001 Differ. Geom. Appl. 15 47-57) d_{{{G}_{0}}, Ω }^{∞}({{g}_{α }}, {{F}_{θ}}) is bounded below by a constant depending only on the rotation frequency of Gödel's universe, thus giving a measure of the bias of {{g}_{α}} from being Fefferman like in the region Ω \\subset {{{R}}^{4}}.

  18. The Del Mod System: An External Evaluation, Final Report, Volume IV.

    ERIC Educational Resources Information Center

    Humphreys, Donald W.; And Others

    This is one of five volumes prepared to describe various aspects of the Del Mod System. This volume deals with the evaluation of the Del Mod System. Included are the following: (1) Del Mod Responsive Evaluation; (2) Evaluation Outcomes; (3) Validation of the Del Mod Responsive Evaluation Process; and (4) Conclusions. Appendices include: (A)…

  19. A Descriptive Analysis of the Del Mod System's Field Agent Component, Final Report, Volume III.

    ERIC Educational Resources Information Center

    Golts, Uldis R.

    This monograph describes the field agent of the Delaware Del Mod System. The following sections are included in the report: (1) The Duties and Activities of the Del Mod System Field Agents; (2) The Field Agents' Mode of Operation; (3) The Conduct of Projects; (4) The Hiring and Training of Del Mod Field Agents; (5) The Administration of Del Mod…

  20. The Love of a Good Narrative: Textuality and Digitality

    ERIC Educational Resources Information Center

    Dobson, Teresa M.

    2006-01-01

    It has often been observed that Alice Munro is a master of narrative complexity. "The love of a good woman", in particular, is a story that challenges conventional notions of structure in short fiction through digression or deferral, discontinuity, layering, and so on. Ross (2002) rightly observes that conventional theories of reading fail to get…

  1. Africa and International Policy Making for Lifelong Learning: Textual Revelations

    ERIC Educational Resources Information Center

    Preece, Julia

    2013-01-01

    This paper discusses the relationship between international agendas for lifelong learning and financial aid for low income countries, especially those on the African continent. It argues that there are subtle differences in terminology written by policymakers respectively in Europe and South Africa for lifelong learning but that international…

  2. Oraliteracy and Textual Opacity: Resisting Metropolitan Consumption of Caribbean Creole

    ERIC Educational Resources Information Center

    Sheller, Mimi

    2004-01-01

    The incorporation of "creole" vernacular languages into texts written in "standard" languages is an especially fraught crossroads of intercultural communication. This article considers the difference between a kind of literary tourism in which non-Caribbean readers "taste" the flavour of creole language within Caribbean literature versus an…

  3. Integrating Animations, Narratives and Textual Information for Improving Physics Learning

    ERIC Educational Resources Information Center

    Adegoke, Benson Adesina

    2010-01-01

    Introduction: This article examined the effect of multimedia instruction on students' learning outcomes (achievement and interest) in secondary school physics. Method: The sample comprised of 517 (294 boys and 223 girls) students who came from 12 senior secondary schools in Ibadan Educational Zone 1, Oyo State, Nigeria. Their ages ranged between…

  4. "Wrighting" the Self: New Technologies and Textual Subjectivities

    ERIC Educational Resources Information Center

    Sakr, Mona

    2012-01-01

    The expression of the self through multimodal texts is a central theme in education. While it has been suggested that new technologies act as important mediators in the relationship between texts and subjectivity, the mechanisms underlying such mediation has been a neglected topic of research. This paper considers the theoretical assumptions upon…

  5. Textual inference for eligibility criteria resolution in clinical trials.

    PubMed

    Shivade, Chaitanya; Hebert, Courtney; Lopetegui, Marcelo; de Marneffe, Marie-Catherine; Fosler-Lussier, Eric; Lai, Albert M

    2015-12-01

    Clinical trials are essential for determining whether new interventions are effective. In order to determine the eligibility of patients to enroll into these trials, clinical trial coordinators often perform a manual review of clinical notes in the electronic health record of patients. This is a very time-consuming and exhausting task. Efforts in this process can be expedited if these coordinators are directed toward specific parts of the text that are relevant for eligibility determination. In this study, we describe the creation of a dataset that can be used to evaluate automated methods capable of identifying sentences in a note that are relevant for screening a patient's eligibility in clinical trials. Using this dataset, we also present results for four simple methods in natural language processing that can be used to automate this task. We found that this is a challenging task (maximum F-score=26.25), but it is a promising direction for further research. PMID:26376462

  6. Combination of visual and textual similarity retrieval from medical documents.

    PubMed

    Eggel, Ivan; Müller, Henning

    2009-01-01

    Medical visual information retrieval has been an active research area over the past ten years as an increasing amount of images are produced digitally and have become available in patient records, scientific literature, and other medical documents. Most visual retrieval systems concentrate on images only, but it has become apparent that the retrieval of similar images alone is of limited interest, and rather the retrieval of similar documents is an important domain. Most medical institutions as well as the World Health Organization (WHO) produce many complex documents. Searching them, including a visual search, can help finding important information and also facilitates the reuse of document content and images. The work described in this paper is based on a proposal of the WHO that produces large amounts of documents from studies but also for training. The majority of these documents are in complex formats such as PDF, Microsoft Word, Excel, or PowerPoint. Goal is to create an information retrieval system that allows easy addition of documents and search by keywords and visual content. For text retrieval, Lucene is used and for image retrieval the GNU Image Finding Tool (GIFT). A Web 2.0 interface allows for an easy upload as well as simple searching. PMID:19745431

  7. Gross's Anatomy: Textual Politics in Science/Biology Education Research

    ERIC Educational Resources Information Center

    Reis, Giuliano

    2009-01-01

    In approaching how the grotesque is--or should be--situated within contemporary science (biology) education practices, Weinstein and Broda undertake a passionate reclaim of an education that is at the same time scientific, critical, and liberatory. However legitimate, their work offers more than they probably could have anticipated: It exemplifies…

  8. Teaching Textual Conversations: Intertextuality in the College Reading Classroom

    ERIC Educational Resources Information Center

    Armstrong, Sonya L.; Newman, Mary

    2011-01-01

    In this article, a model of intertextuality is introduced as an instructional approach for postsecondary developmental reading courses. This model involves a scaffolded, schema building approach to teaching college reading that aims to link core material (a text, a concept, or specific academic content) with supplementary texts that focus on…

  9. Lifeworld and Textualism: Reassembling the Researcher/ed and "Others"

    ERIC Educational Resources Information Center

    Payne, Phillip G.

    2005-01-01

    This response to McKenzie's "post-post" concerns about environmental education research draws upon empirical, conceptual, anecdotal, metaphorical, imaged and poetic means to help the researcher "reassemble" the researcher/ed by attending to her/his relational body and embodiment of various, often hegemonic, socially constructed environmental…

  10. Achieving Science Literacy through Transformation of Multimodal Textual Resources

    ERIC Educational Resources Information Center

    Knain, Erik

    2006-01-01

    In her article "Framing New Research in Science Literacy and Language Use: Authenticity, Multiple Discourses, and the "Third Space"," Carolyn S. Wallace presented a model of science literacy that frames language in science to teaching principles in a powerful way. The model would however be enhanced if two additional concepts are made explicit,…

  11. A Template Engine for Parsing Objects from Textual Representations

    NASA Astrophysics Data System (ADS)

    Rajković, Milan; Stanković, Milena; Marković, Ivica

    2011-09-01

    Template engines are widely used for separation of business and presentation logic. They are commonly used in web applications for clean rendering of HTML pages. Another area of usage is message formatting in distributed applications where they transform objects to appropriate representations. This paper explores the possibility of using templates for a reverse process—for creating objects starting from their representations. We present the prototype of engine that we have developed, and describe benefits and drawbacks of this approach.

  12. A Data Model for Use with Formatted and Textual Data.

    ERIC Educational Resources Information Center

    Desai, B. C.; And Others

    1986-01-01

    Presents data model based on text data model (TDM), universal relation model, and nonfirst normal form (NFNF) relations, and discusses applicability to text processing and document retrieval systems. Highlights include database technology applied to information retrieval, NFNF and universal relation, and TDM integration with NFNF universal…

  13. Age-Related Differences in the Production of Textual Descriptions

    ERIC Educational Resources Information Center

    Marini, Andrea; Boewe, Anke; Caltagirone, Carlo; Carlomagno, Sergio

    2005-01-01

    Narratives produced by 69 healthy Italian adults were analyzed for age-related changes of microlinguistic, macrolinguistic and informative aspects. The participants were divided into five age groups (20-24, 25-39, 40-59, 60-74, 75-84). One single-picture stimulus and two cartoon sequences were used to elicit three stories per subject. Age-related…

  14. Critical Theory & Textual Arguments: Expanding Habermas's Analysis of Literary Claims.

    ERIC Educational Resources Information Center

    Stroud, Scott R.

    Jurgen Habermas's theory of communicative action has held much promise for critical theory and its examination of the structure of society. This theory, however, has been accused by some as being limited in regard to other forms of discourse, especially fictional, mythical, and religious texts. Habermas has argued that literature (i.e., fictive…

  15. A Close Textual Analysis of Corporate Layoff Memos

    ERIC Educational Resources Information Center

    Warnick, Quinn

    2010-01-01

    All employers occasionally must deliver bad news to their employees, but few bad news situations can compete with the delicate task of announcing layoffs. In an electronic age, when layoff notices delivered via email are quickly leaked to outsiders, CEOs must take into account not only the employees who will be affected by the layoffs but also the…

  16. Once Is Not Enough: Statistical Simulation of Textual Data.

    ERIC Educational Resources Information Center

    Hogenraad, Robert

    Reproduction is part of the regulations of daily speech. Everyday experience shows there are different ways to convey the same information: starting sentences that are quickly rephrased using other words, manuscripts passing through draft states before the writer decides upon the final version. In more ways than one, any text is always but the…

  17. Textual representations of diversity in COAMFTE accredited doctoral programs.

    PubMed

    Lawless, John J; Brooks, Stephanie; Julye, Stacey

    2006-01-01

    The use of the Internet is growing at a staggering pace. One significant use of the Internet is for potential students and the parents of potential students to explore educational possibilities. Along these lines potential marriage and family therapy students may have many questions that include a program's commitment to cultural diversity. This study utilized qualitative content analysis methodology in combination with critical race theory to examine how Commission On Accreditation for Marriage and Family Therapy Education (COAMFTE) accredited doctoral programs represented cultural text on their World Wide Web pages. Findings indicate that many COAMFTE-accredited doctoral programs re-present programmatic information about diversity that appear to be incongruent with cultural sensitivity. These apparent incongruities are highlighted by the codification, inconsistent, and isolated use of cultural text. In addition, cultural text related to social justice was absent. Implications and suggestions are discussed. PMID:16468677

  18. Textual Challenges: A Brief Guide to Choosing Shakespearean Editions

    ERIC Educational Resources Information Center

    Cornell, Christine; Malcolmson, Patrick

    2012-01-01

    How should educators go about selecting appropriate editions of Shakespeare's plays for use in political science courses? Shakespeare is turning up on many politics syllabi, but, at times, the editions chosen seem to reflect primarily a concern for price or publisher reputation over pedagogical and scholarly considerations. This article offers an…

  19. Applications of N-Grams in Textual Information Systems.

    ERIC Educational Resources Information Center

    Robertson, Alexander M.; Willett, Peter

    1998-01-01

    An n-gram is a string of characters, usually adjacent, extracted from a section of continuous text that can be used in spelling error detection and correction, query expansion, information retrieval, dictionary search, text compression, and language identification applications. This article provides an introduction to the use of n-grams in textual…

  20. Knowledge Discovery in Textual Documentation: Qualitative and Quantitative Analyses.

    ERIC Educational Resources Information Center

    Loh, Stanley; De Oliveira, Jose Palazzo M.; Gastal, Fabio Leite

    2001-01-01

    Presents an application of knowledge discovery in texts (KDT) concerning medical records of a psychiatric hospital. The approach helps physicians to extract knowledge about patients and diseases that may be used for epidemiological studies, for training professionals, and to support physicians to diagnose and evaluate diseases. (Author/AEF)

  1. Constructing and Analyzing Uncertain Social Networks from Unstructured Textual Data

    NASA Astrophysics Data System (ADS)

    Johansson, Fredrik; Svenson, Pontus

    Social network analysis and link diagrams are popular tools among intelligence analysts for analyzing and understanding criminal and terrorist organizations. A bottleneck in the use of such techniques is the manual effort needed to create the network to analyze from available source information. We describe how text mining techniques can be used for extraction of named entities and the relations among them, in order to enable automatic construction of networks from unstructured text. Since the text mining techniques used, viz. algorithms for named entity recognition and relation extraction, are not perfect, we also describe a method for incorporating information about uncertainty when constructing the networks and when doing the social network analysis. The presented approach is applied on text documents describing terrorist activities in Indonesia.

  2. Cockpit data link displays - An evaluation of textual formats

    NASA Technical Reports Server (NTRS)

    Mcgann, Alison; Lozito, Sandra; Corker, Kevin

    1992-01-01

    Data link technologies are being investigated for air/ground information transfer for commercial aircraft operation. This study was designed to measure which of four alpha-numeric display formats for display of data link information would lead to the quickest and most accurate memory retrieval in a part-task simulation environment. Pilots viewed a clearance for 10-15 seconds and were subsequently queried about the content of that clearance. Speed and accuracy of responses were measured across three retention tasks. The three retention tasks included free recall of a particular clearance. recognition of a previous clearance, and the comparison of element values between a previously displayed and current clearance. Each format was tested with and without a distraction task. Subjective ratings of each format were also collected. The analyses revealed no significant differences for reaction time or accuracy among the four formats. Explanations for these results as well as alternative methodologies are discussed.

  3. Some Considerations of Intersubjectivity in the Analysis of Textual Relations.

    ERIC Educational Resources Information Center

    Koskela, Merja

    A study explored the reliability of methods for analyzing the thematic organization of texts. Five linguists, two of whom were native speakers of Swedish and three of whom were native speakers of Finnish, analyzed the thematic organization of a Swedish popular scientific article, using an analysis that focused on coherence reflected in the…

  4. Agent-based method for distributed clustering of textual information

    DOEpatents

    Potok, Thomas E [Oak Ridge, TN; Reed, Joel W [Knoxville, TN; Elmore, Mark T [Oak Ridge, TN; Treadwell, Jim N [Louisville, TN

    2010-09-28

    A computer method and system for storing, retrieving and displaying information has a multiplexing agent (20) that calculates a new document vector (25) for a new document (21) to be added to the system and transmits the new document vector (25) to master cluster agents (22) and cluster agents (23) for evaluation. These agents (22, 23) perform the evaluation and return values upstream to the multiplexing agent (20) based on the similarity of the document to documents stored under their control. The multiplexing agent (20) then sends the document (21) and the document vector (25) to the master cluster agent (22), which then forwards it to a cluster agent (23) or creates a new cluster agent (23) to manage the document (21). The system also searches for stored documents according to a search query having at least one term and identifying the documents found in the search, and displays the documents in a clustering display (80) of similarity so as to indicate similarity of the documents to each other.

  5. On Becoming Textually Active at Youthline, New Zealand

    ERIC Educational Resources Information Center

    Haxell, Ailsa Janet

    2015-01-01

    The phones hardly ring at Youthline New Zealand anymore; youth still have problems and seek help, but it mostly happens silently. This article reports on experiences of texting at a 24-hour crisis helpline for young people. To date, there has been no formal evidence base for this practice; however, for new practice, there never is. In prompting…

  6. Centro para la Salud Mundial (CGH) del NCI

    Cancer.gov

    El Centro para la Salud Mundial (CGH) del NCI coordina actividades de investigación y trabaja con socios nacionales e internacionales para comprender y enfrentar la carga que representa el cáncer a nivel mundial.

  7. Living Legacy: A Conversation with Carolina Gomez del Valle.

    ERIC Educational Resources Information Center

    Montessori Life, 1993

    1993-01-01

    Carolina Gomez del Valle has been involved in training other Montessorians in Mexico, Chile, Nicaragua, Peru, and Taiwan. This interview explores her experiences with Montessori education and describes how she has woven her religious training and Montessori philosophy together. (PAM)

  8. 88. Paso Del Norte Hotel, 115117 South El Paso St., ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    88. Paso Del Norte Hotel, 115-117 South El Paso St., south facade, west side of street - South El Paso Street Historic District, South El Paso, South Oregon & South Santa Fe Streets, El Paso, El Paso County, TX

  9. 91. Paso Del Norte Hotel, 115117 South El Paso St., ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    91. Paso Del Norte Hotel, 115-117 South El Paso St., east facade, west side of street - South El Paso Street Historic District, South El Paso, South Oregon & South Santa Fe Streets, El Paso, El Paso County, TX

  10. PASO DEL NORTE HOTEL, 115117 S. EL PASO ST., SOUTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PASO DEL NORTE HOTEL, 115-117 S. EL PASO ST., SOUTH AND EAST FACADES, WEST SIDE OF STREET - South El Paso Street Historic District, South El Paso, South Oregon & South Santa Fe Streets, El Paso, El Paso County, TX

  11. 92. Paso Del Norte Hotel, 115117 South El Paso St., ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    92. Paso Del Norte Hotel, 115-117 South El Paso St., interior, lobby rotunda - South El Paso Street Historic District, South El Paso, South Oregon & South Santa Fe Streets, El Paso, El Paso County, TX

  12. PASO DEL NORTE HOTEL, 115117 S. EL PASO ST., EAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PASO DEL NORTE HOTEL, 115-117 S. EL PASO ST., EAST FACADE, WEST SIDE OF STREET - South El Paso Street Historic District, South El Paso, South Oregon & South Santa Fe Streets, El Paso, El Paso County, TX

  13. Se evitaron casi 800 000 muertes por descenso del tabaquismo

    Cancer.gov

    Programas y estrategias de control del tabaco del siglo XX fueron responsables de la prevención de más de 795 000 muertes por cáncer de pulmón en Estados Unidos de 1975 al 2000. Si todo el tabaquismo en este país hubiera cesado después de la publicación d

  14. Estudio del sistema simbiótico AR Pavonis

    NASA Astrophysics Data System (ADS)

    Quiroga, C.; Brandi, E.; Ferrer, O.; García, L.; Barbá, R.

    Se presenta un estudio espectroscópico y polarimétrico de la binaria eclipsante AR Pavonis a partir de observaciones obtenidas con el telescopio de 2.15 m. del CASLEO (San Juan). El estudio de la naturaleza del sistema se realizó a través del análisis de algunos espectros reunidos entre los años 1990 y 1995 y de datos polarimétricos correspondientes al intervalo 1995 y 1997. El análisis espectroscópico indica que AR Pav está compuesta por una gigante roja M3.7 y una componente caliente compacta, con una temperatura mayor a 90000 K y una luminosidad del orden de 500Lsolar. A lo largo del período orbital, las variaciones observadas en flujo y en velocidades radiales, reflejan que las emisiones permitidas se forman en una región que rodea la componente caliente. El estudio de la polarización lineal de AR Pav indica que además de una componente interestelar, existe una componente intrínseca del sistema que varía temporalmente y con la longitud de onda de la luz polarizada. El distinto comportamiento del grado de polarización y del ángulo de posición observado en fases diferentes, sugiere que distintos mecanismos pueden estar actuando, dependiendo de la región de scattering observado a lo largo de la línea de la visual.

  15. 65. Photographer unknown March 1931 DEL NORTE COUNTY, SECTION B, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    65. Photographer unknown March 1931 DEL NORTE COUNTY, SECTION B, HIGHWAY 1, 1-DN-1-B #66A, STA. 166.0+00 WIDENED ROADBED BEFORE COVERING LOG CRIB, 3-31. BACK READS: WIDENING ROAD BED WITH LOGS, APPROX 30 SQUARE & 60 LONG ON DN-1 SEC B STA 156+. Stamped office copy, - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  16. Extreme Environments in Tierra del Fuego, Argentina

    NASA Astrophysics Data System (ADS)

    Schultz, C.; D'Antoni, H.; Burgess, S.; Zamora, J.; Skiles, J.

    2007-12-01

    The upper timberline of the Andes Cordillera on the island of Tierra del Fuego at the tip of South America is an environment subject to extreme conditions. In order to further understand this environment, ecosystem parameters were measured within two transects of the Andes at Glaciar Martial and Cerro Guanaco. The measurements included pH, soil temperature, soil moisture, nitrogen, sodium and potassium concentration, chlorophyll absorbance, and irradiance in the ultraviolet range (200-400 nm). These data comprise a survey that serves as a baseline for an intensive research program. Chlorophyll concentration and soil data were within the range of our observations at several other sites, from Lapataia Bay on the southwestern boundary with Chile, through the eastern end of Lake Fagnano. However, unusual levels of solar irradiance were found in the open sites of both transects while those in the forest exhibited lower UV values, suggesting strong absorption and/or reflection by the forest canopy. High levels of UV radiation damage important biomolecules and may be partially responsible for the presence of life forms such as the krummholz belt in the upper timberline. These UV values may be due to the effects of global ozone depletion and the ozone hole. The low temperatures, strong winds, snow and ice-covered soil and especially the exposure to UV radiation make this area an extreme environment for life.

  17. Alloimmunization of patients by blood units harboring distinct DEL variants.

    PubMed

    St-Louis, Maryse; Lebrun, André; Goldman, Mindy; Lavoie, Marianne

    2013-01-01

    The alloimmunization potential of many RHD variants is unknown, and it can be explored by lookback and traceback studies. Hema-Quebec (HQ) investigated the RHD status of 3980 D- repeat blood donors. Thirteen were found to be RHD positive: 4 RHD*1p, and 1 RHD*487delACAG, which show a Dphenotype;and 1 RHD*885T and 7 RHD*(93-94insT) causing a DEL phenotype when C antigen is present. Look back studies were done to verify the alloimmunization potential of these eight DEL donors. Coincidentally, Canadian Blood Services (CBS)performed a trace back study by investigating the RHD status of donors after aD- recipient developed anti-Dafter transfusion of two D- red blood cell (RBC) units. Donor genotyping was done either manually (HQ) or using the Progenika Bloodchip platform(CBS). Donations were traced through computer records. Letters were sent to hospital blood bank physicians to verify the presence of anti-Din recipients and to donors to request repeat samples.A total of 118 RBC units were transfused, 82 to D- recipients.Anti-D was found in three patients transfused with RHD*(93-94insT) DEL red blood cells. One donor presenting the same DEL variant was involved in the trace back study. Even without strong evidence clearly demonstrating the alloimmunization potential of DEL variants, whenever HQ or CBS identifies a donor harboring a DEL phenotype, his or her D status will be changed from DtoD+ to protect against the potential alloimmunization risk. PMID:24689683

  18. May Gödel's Ideas Be Addressed Philosophically?

    NASA Astrophysics Data System (ADS)

    Dokulil, Miloš

    2007-11-01

    del emphasised philosophy as an important tool in science. Much less is known about his religious background. We should bear in mind that our evaluational perspective differs very much from the one in which Gödel lived. He was personally sure that there must be another existence after death-an afterlife (''of unlimited life span''). As a ''Baptized Lutheran'' he did not include ''Trinity'' in his creed. He was also certain that mind is separate from matter. This text tries to include Libet's ''readiness potential'' into the debate concerning the specificity of the mind. Neither Gödel's identification of materialism with mechanism nor his vision of the ''spirit'' are a viable solution of the problem.

  19. Field measurements of del13C in ecosystem respiration

    NASA Astrophysics Data System (ADS)

    van Asperen, Hella; Sabbatini, Simone; Nicolini, Giacomo; Warneke, Thorsten; Papale, Dario; Notholt, Justus

    2014-05-01

    Stable carbon isotope del13C-measurements are extensively used to study ecological and biogeochemical processes in ecosystems. Above terrestrial ecosystems, atmospheric del13C can vary largely due to photosynthetic fractionation. Photosynthetic processes prefer the uptake of the lighter isotope 12C (in CO2), thereby enriching the atmosphere in 13C and depleting the ecosystem carbon. At night, when ecosystem respiratory fluxes are dominant, 13C-depleted CO2 is respired and thereby depletes the atmospheric del13C-content. Different ecosystems and different parts of one ecosystem (type of plant, leaves, and roots) fractionate and respire with a different del13C-ratio signature. By determining the del13C-signature of ecosystem respiration in temporal and spatial scale, an analysis can be made of the composition of respiratory sources of the ecosystem. A field study at a dry cropland after harvest (province of Viterbo, Lazio, Italy) was performed in the summer of 2013. A FTIR (Fourier Transform Infrared Spectrometer) was set up to continuously measure CO2-, CH4-, N2O-, CO- and del13C-concentrations. The FTIR was connected to 2 different flux measurements systems: a Flux Gradient system (sampling every half hour at 1.3m and 4.2m) and 2 flux chambers (measured every hour), providing a continuous data set of the biosphere-atmosphere gas fluxes and of the gas concentrations at different heights. Keeling plot intercept values of respiratory CO2, measured by the Flux Gradient system at night, were determined to be between -25‰ and -20‰. Keeling plot intercept values of respiratory CO2, measured by the flux chamber system, varied between -24‰ and -29‰, and showed a clear diurnal pattern, suggesting different (dominant) respiratory processes between day and night.

  20. Symmetries of geodesic motion in Gödel-type spacetimes

    SciTech Connect

    Camci, U.

    2014-07-01

    In this paper, we study Noether gauge symmetries of geodesic motion for geodesic Lagrangian of four classes of metrics of Gödel-type spacetimes for which we calculated the Noether gauge symmetries for all classes I-IV, and find the first integrals of corresponding classes to derive a complete characterization of the geodesic motion. Using the obtained expressions for t-dot , r-dot ,φ-dot and ż of each classes I-IV which depends essentially on two independent parameters m and w, we explicitly integrated the geodesic equations of motion for the corresponding Gödel-type spacetimes.

  1. Outcome following haematopoietic cell transplantation in patients with myelodysplasia and del (5q) karyotypes.

    PubMed

    Stewart, B; Verdugo, M; Guthrie, K A; Appelbaum, F; Deeg, H J

    2003-12-01

    The deletion (5q) karyotype [del (5q)] in patients with myelodysplastic syndrome (MDS) is considered a good risk feature, while the impact of del (5q) combined with other karyotypic abnormalities [del (5q)+] is less well defined. We analysed the outcome of haematopoietic cell transplants (HCT) in patients with MDS with del (5q) or del (5q)+. Fifty-seven patients, aged 6-72 years, with MDS and del (5q) abnormalities received HCT from related (n = 32) or unrelated (n = 25) donors. By French-American-British (FAB) criteria, 27 patients had refractory anaemia (RA), 10 RA with excess blasts (RAEB), eight RAEB in transformation (RAEB-T) and 12 acute myeloid leukaemia evolving from MDS (tAML). Non-relapse mortality at 1-year post-transplantation was 30% for del (5q) and 38% for del (5q)+ patients. Relapse occurred in one of 20 del (5q) patients and 15 of 37 del (5q)+ patients (P = 0.001). After adjusting for del (5q) status, blast count (<5%) was the only factor significantly associated with relapse-free survival. Patients with del (5q), either as a '5q- syndrome' or with MDS in general, had better outcomes than did patients with del (5q)+. The indication for transplantation in patients with del (5q) was generally severe cytopenias, compared with disease progression to a more advanced FAB stage in patients with del (5q)+. Conceivably, outcome for patients with del (5q)+ would be improved with transplantation earlier in the disease course. PMID:14632779

  2. 77 FR 50080 - Del Norte County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-20

    ...The Del Norte County Resource Advisory Committee (RAC) will meet in Crescent City, California. The committee is authorized under the Secure Rural Schools and Community Self-Determination Act (Pub. L. 112-141) (the Act) and operates in compliance with the Federal Advisory Committee Act. The purpose of the committee is to improve collaborative relationships and to provide advice and......

  3. Síntesis: Resultados iniciales del Estudio Nacional de Ex

    Cancer.gov

    El 4 de noviembre de 2010, el Estudio Nacional de Exámenes de Pulmóndio a conocer resultados iniciales que indican que hubo 20% menos muertes por cáncer de pulmón entre los participantes del estudio evaluados con tomografía computarizada espiral de baja d

  4. Faculty Activity Analysis in the Universidad Tecnica Del Estado Campuses.

    ERIC Educational Resources Information Center

    Karadima, Oscar

    An analysis of academic activities of college faculty at the eight campuses of Chile's Universidad Tecnica del Estado was conducted. Activities were grouped into seven categories: direct teaching, indirect teaching, research, community services, faculty development, academic administration, and other activities. Following the narrative…

  5. Interdisciplinary Unit: La Isla del Encanto (The Enchanted Island).

    ERIC Educational Resources Information Center

    Ford-Guerrera, Rebecca

    This document presents a series of 14 lesson plans in an interdisciplinary Spanish unit on "La isla del encanto/The Enchanted Island." The materials were prepared for students in grades 5 or 6 who have had basic Spanish instruction in previous grades. The students should also be familiar with basic concepts in English such as math computation, map…

  6. Design, aerodynamics and autonomy of the DelFly.

    PubMed

    de Croon, G C H E; Groen, M A; De Wagter, C; Remes, B; Ruijsink, R; van Oudheusden, B W

    2012-06-01

    One of the major challenges in robotics is to develop a fly-like robot that can autonomously fly around in unknown environments. In this paper, we discuss the current state of the DelFly project, in which we follow a top-down approach to ever smaller and more autonomous ornithopters. The presented findings concerning the design, aerodynamics and autonomy of the DelFly illustrate some of the properties of the top-down approach, which allows the identification and resolution of issues that also play a role at smaller scales. A parametric variation of the wing stiffener layout produced a 5% more power-efficient wing. An experimental aerodynamic investigation revealed that this could be associated with an improved stiffness of the wing, while further providing evidence of the vortex development during the flap cycle. The presented experiments resulted in an improvement in the generated lift, allowing the inclusion of a yaw rate gyro, pressure sensor and microcontroller onboard the DelFly. The autonomy of the DelFly is expanded by achieving (1) an improved turning logic to obtain better vision-based obstacle avoidance performance in environments with varying texture and (2) successful onboard height control based on the pressure sensor. PMID:22617112

  7. Cosmogenic Radionuclides in the Campo Del Cielo Iron Meteorite

    NASA Technical Reports Server (NTRS)

    Liberman, R. G.; FernandezNiello, J. O.; Reedy, R. C.; Fifield, L. K.; diTada, M. L.

    2001-01-01

    Cosmogenic Be-10, Al-26, Cl-36, Ca-41, and Ni-59 were measured in the Campo del Cielo iron meteorite. Our results led us to conclude that the pre-atmospheric radius might have been approximately 2 m. Comparisons with other big bodies are also presented. Additional information is contained in the original extended abstract.

  8. 87. Paso Del Norte Hotel, 115117 South El Paso St., ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    87. Paso Del Norte Hotel, 115-117 South El Paso St., south and east facades, west side of street - South El Paso Street Historic District, South El Paso, South Oregon & South Santa Fe Streets, El Paso, El Paso County, TX

  9. 89. Paso Del Norte Hotel, 115117 South El Paso St., ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    89. Paso Del Norte Hotel, 115-117 South El Paso St., detail view of roof, west side of street - South El Paso Street Historic District, South El Paso, South Oregon & South Santa Fe Streets, El Paso, El Paso County, TX

  10. Cirugía de los trastornos del comportamiento: el estado del arte

    PubMed Central

    Yampolsky, Claudio; Bendersky, Damián

    2014-01-01

    Introducción: La cirugía de los trastornos del comportamiento (CTC) se está convirtiendo en un tratamiento más común desde el desarrollo de la neuromodulación. Métodos: Este artículo es una revisión no sistemática de la historia, indicaciones actuales, técnicas y blancos quirúrgicos de la CTC. Dividimos su historia en 3 eras: la primera comienza en los inicios de la psicocirugía y termina con el desarrollo de las tícnicas estereotácticas, cuando comienza la segunda era. Ésta se caracteriza por la realización de lesiones estereotácticas. Nos encontramos transitando la tercera era, que comienza cuando la estimulación cerebral profunda (ECP) comienza a ser usada en CTC. Resultados: A pesar de los errores graves cometidos en el pasado, hoy en día, la CTC está renaciendo. Los trastornos psiquiátricos que se más frecuentemente se tratan con cirugía son: depresión refractaria, trastorno obsesivo-compulsivo y síndrome de Tourette. Además, algunos pacientes con agresividad fueron tratados quirúrgicamente. Hay varios blancos estereotácticos descriptos para estos trastornos. La estimulación vagal puede ser usada también para depresión. Conclusión: Los resultados de la ECP en estos trastornos parecen alentadores. Sin embargo, se necesitan más estudios randomizados para establecer la efectividad de la CTC. Debe tenerse en cuenta que una apropiada selección de pacientes nos ayudará a realizar un procedimiento más seguro así como también a lograr mejores resultados quirúrgicos, conduciendo a la CTC a ser más aceptada por psiquiatras, pacientes y sus familias. Se necesita mayor investigación en varios temas como: fisiopatología de los trastornos del comportamiento, indicaciones de CTC y nuevos blancos quirúrgicos. PMID:25165612

  11. Preguntas para hacerle al doctor acerca del cáncer

    Cancer.gov

    Serie de preguntas, organizadas por tema, que los pacientes con cáncer pueden hacer al médico o a otros miembros de su equipo de atención médica para conocer más acerca de su tipo de cáncer y lo que pueden esperar.

  12. Del Mod at a Glance, Volume 3. 1973-1974 Annual Report for the Del Mod System.

    ERIC Educational Resources Information Center

    Bolig, John R.

    A synopsis of the 1973-74 annual report for the Del Mod System is presented. The activities described were conducted by the University of Delaware, Delaware State College, Delaware Technical and Community College, and the Department of Public Instruction. Activities of field agents, several local district projects, and individual teacher grants…

  13. Extensión del Formalismo de Orbitales de Defecto Cuántico al tratamiento del efecto Stark (SQDO).

    NASA Astrophysics Data System (ADS)

    Menéndez, J. M.; Martín, I.; Velasco, A. M.

    El estudio experimental de las interacciones de átomos Rydberg altamente excitados con campos eléctricos ha experimentado un creciente interés durante las dos últimas décadas debido, en gran medida, al desarrollo de nuevas técnicas para crear y estudiar átomos Rydberg en el laboratorio. Acompañando a estas nuevas técnicas experimentales, es necesario el desarrollo de modelos teóricos que nos permitan contrastar sus medidas y conocer mejor los fundamentos de los mismos. Desde el punto de vista teórico el conocimiento del desdoblamiento de los niveles energéticos de un átomo en función de la magnitud del campo eléctrico aplicado (lo que se conoce como mapa Stark) es el mejor punto de partida para la descripción del sistema y un prerrequisito fundamental para el cálculo de distintas propiedades atómicas en presencia del campo eléctrico tales como intensidades de transición, umbrales de ionización de campo eléctrico, tiempos de vida, posición y anchura de cruces evitados, etc. En este trabajo presentamos la adaptación del método de orbitales de defecto cuántico [1,2,3] al tratamiento del efecto Stark (SQDO) [4] y su aplicación al cálculo de los desdoblamientos energéticos y fuerzas de oscilador de estados Rydberg en los átomos de Li, Na y K. El propósito de este estudio es, por un lado, desarrollar métodos fiables para la determinación de propiedades atómicas en presencia de campos eléctricos y, por otro, mostrar la fiabilidad de las funciones de onda QDO en la descripción del efecto Stark en sistemas atómicos.

  14. Analisis del contenido curricular de los Documentos Normativos del Programa de Ciencias en el area de biologia para la escuela superior del sistema de educacion publica de Puerto Rico: 1993-2012

    NASA Astrophysics Data System (ADS)

    Davila Montanez, Melissa

    Esta investigacion de naturaleza cualitativa se ocupo de realizar un analisis de contenido documental de los Documentos Normativos del Programa de Ciencias en el area de biologia de la escuela superior del sistema de educacion publica de Puerto Rico del periodo 1993-2012. Los documentos analizados fueron: Guia Curricular, 1995; Marco Curricular, 2003; Estandares de Excelencia, 1996, 2000 y Estandares de Contenido y Expectativas de Grado, 2007. Se indago si hubo cambios en significados en los Componentes Estructurales: Naturaleza de la ciencia, Paradigmas para la ensenanza de la ciencia, Funcion del curriculo formal, Mision de la ensenanza de la ciencia; Contenidos, destrezas y competencias, Estrategias de ensenanza y Evaluacion/Assessment del aprendizaje. El analisis sugiere que no hubo cambios sustanciales en los significados de los Componentes Estructurales. Los documentos estudiados muestran mayormente caracteristicas similares, aunque los documentos mas recientes eran mas descriptivos, explicativos y especificos.

  15. Genomic Copy Number Variations in the Myelodysplastic Syndrome and Acute Myeloid Leukemia Patients with del(5q) and/or -7/del(7q).

    PubMed

    Zhang, Rui; Kim, Young-Mi; Wang, Xianfu; Li, Yan; Lu, Xianglan; Sternenberger, Andrea R; Li, Shibo; Lee, Ji-Yun

    2015-01-01

    The most common chromosomal abnormalities in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) are -5/del(5q) and -7/del(7q). When -5/del(5q) and -7/del(7q) coexist in patients, a poor prognosis is typically associated. Given that -5/del(5q) and/or -7/del(7q) often are accompanied with additional recurrent chromosomal alterations, genetic change(s) on the accompanying chromosome(s) other than chromosomes 5 and 7 may be important factor(s) affecting leukemogenesis and disease prognosis. Using an integrated analysis of karyotype, FISH and array CGH results in this study, we evaluated the smallest region of overlap (SRO) of chromosomes 5 and 7 as well as copy number alterations (CNAs) on the other chromosomes. Moreover, the relationship between the CNAs and del(5q) and -7/del(7q) was investigated by categorizing the cases into three groups based on the abnormalities of chromosomes 5 and 7 [group I: cases only with del(5q), group II: cases only with -7/del(7q) and group III: concurrent del(5q) and del(7q) cases]. The overlapping SRO of chromosome 5 from groups I and III was 5q31.1-33.1 and of chromosome 7 from groups II and III was 7q31.31-q36.1. A total of 318 CNAs were observed; ~ 78.3% of them were identified on chromosomes other than chromosomes 5 and 7, which were defined as 'other CNAs'. Group III was a distinctive group carrying the most high number (HN) CNAs, cryptic CNAs and 'other CNAs'. The loss of TP53 was highly associated with del(5q). The loss of ETV6 was specifically associated with group III. These CNAs or genes may play a secondary role in disease progression and should be further evaluated for their clinical significance and influence on therapeutic approaches in patients with MDS/AML carrying del(5q) and/or -7/del(7q) in large-scale, patient population study. PMID:26392809

  16. Genomic Copy Number Variations in the Myelodysplastic Syndrome and Acute Myeloid Leukemia Patients with del(5q) and/or -7/del(7q)

    PubMed Central

    Zhang, Rui; Kim, Young-Mi; Wang, Xianfu; Li, Yan; Lu, Xianglan; Sternenberger, Andrea R.; Li, Shibo; Lee, Ji-Yun

    2015-01-01

    The most common chromosomal abnormalities in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) are -5/del(5q) and -7/del(7q). When -5/del(5q) and -7/del(7q) coexist in patients, a poor prognosis is typically associated. Given that -5/del(5q) and/or -7/del(7q) often are accompanied with additional recurrent chromosomal alterations, genetic change(s) on the accompanying chromosome(s) other than chromosomes 5 and 7 may be important factor(s) affecting leukemogenesis and disease prognosis. Using an integrated analysis of karyotype, FISH and array CGH results in this study, we evaluated the smallest region of overlap (SRO) of chromosomes 5 and 7 as well as copy number alterations (CNAs) on the other chromosomes. Moreover, the relationship between the CNAs and del(5q) and -7/del(7q) was investigated by categorizing the cases into three groups based on the abnormalities of chromosomes 5 and 7 [group I: cases only with del(5q), group II: cases only with -7/del(7q) and group III: concurrent del(5q) and del(7q) cases]. The overlapping SRO of chromosome 5 from groups I and III was 5q31.1-33.1 and of chromosome 7 from groups II and III was 7q31.31-q36.1. A total of 318 CNAs were observed; ~ 78.3% of them were identified on chromosomes other than chromosomes 5 and 7, which were defined as 'other CNAs'. Group III was a distinctive group carrying the most high number (HN) CNAs, cryptic CNAs and 'other CNAs'. The loss of TP53 was highly associated with del(5q). The loss of ETV6 was specifically associated with group III. These CNAs or genes may play a secondary role in disease progression and should be further evaluated for their clinical significance and influence on therapeutic approaches in patients with MDS/AML carrying del(5q) and/or -7/del(7q) in large-scale, patient population study. PMID:26392809

  17. New records of fishes at Isla del Coco, Costa Rica

    USGS Publications Warehouse

    Garrison, V.H.

    1996-01-01

    Isla del Coco lies at 5 degrees 32'N latitude, 87 degrees 04'W longitude and is the sole peak of the Cocos Ridge exposed above sea level. This isolated island formed approximately 2 million years ago. It rises 575 m above the surface of the sea and covers 46 km2 (Castillo et aI., 1988). Five hundred km to the NNE is Costa Rica; 630 km SSW are the Galapagos Islands; 650 km to the E is Isla Malpelo, Colombia; and approximately 8,000 km W lie the Line Islands. Costa Rica claimed Isla del Coco in 1832 and declared it a National Park in 1978. The area of the park was increased to include the adjacent waters 5 km offshore in 1984 and 25 km offshore in 1991.

  18. A model of Nevado del Ruiz Volcano, Colombia

    NASA Astrophysics Data System (ADS)

    Williams, Stanley N.; Meyer, Hansjürgen

    A workshop was held at the Observatorio Vulcanologico de Colombia in Manizales, Colombia, March 28 to April 1, 1988, to review the accumulated data on the disastrous November 13, 1985, eruption and related activity of Nevado del Ruiz volcano (Figure 1). Approximately 30 scientists from eight countries presented data, developed a preliminary model, and addressed the future problems of Ruiz. The volcano (see Figure 2) erupted just prior to the meeting, covering the meeting site with 1-2 mm of ash.The workshop was convened by Stanley N. Williams (Louisiana State University, Baton Rouge) and Hansjürgen Meyer (Universidad del Valle, Cali, Colombia). A special volume of the Journal of Volcanology and Geothermal Research is planned for the papers and letters presented at the workshop, with some additional contributions. Publication is expected in mid-1989.

  19. El ``Aula del Cel'': astronomy approaching high school

    NASA Astrophysics Data System (ADS)

    Ortiz-Gil, A.; Gómez Collado, M.; Gallego Calvente, A. T.

    The “Aula del Cel” is a project carried out by the Astronomical Obsevatory of the University of Valencia, Spain. It offers high-school teachers a tool for teaching Astronomy to 10 to 17 year-old students. Different programs, experiments, and audiovisual presentations have been prepared by a team formed both by professional astronomers and teachers, and are offered in a format chosen to suit each particular age and curriculum group. Special sessions have been designed for students with special needs (for example blind or autistic children) in close contact with the pedagogical teams responsible for their education. Nearly three thousand students have already visited the “Aula del Cel” over the first six months that it has been offered to the school community.

  20. 2. COURSE OF THE LATERAL THROUGH DEL NORTHWEST MAR PARK. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. COURSE OF THE LATERAL THROUGH DEL NORTHWEST MAR PARK. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

  1. 3. 1939 DROP STRUCTURE IN DEL MAR PARK SURMOUNTED BY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. 1939 DROP STRUCTURE IN DEL MAR PARK SURMOUNTED BY RECENT PEDESTRIAN BRIDGE. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

  2. Solar adaptive optics at the Observatorio del Teide, Tenerife

    NASA Astrophysics Data System (ADS)

    Soltau, Dirk; Berkefeld, Thomas; Schmidt, Dirk; von der Lühe, Oskar

    2013-10-01

    Observing the Sun with high angular resolution is difficult because the turbulence in the atmosphere is strongest during day time. In this paper we describe the principles of solar adaptive optics exemplified by the two German solar telescopes VTT and GREGOR at the Observatorio del Teide. With theses systems we obtain near diffraction limited images of the Sun. Ways to overcome the limits of conventional AO by applying multiconjugate adaptive optics (MCAO) are shown.

  3. Determinacion de Caracteristicas Opticas del Telescopio OAN150

    NASA Astrophysics Data System (ADS)

    Galan, M. J.; Cobos, F. J.

    1987-05-01

    En el Observatorio de Calar Alto, en Almería, España, está ubicado un telescopio de 15O-cms de diámetro -construído por REOSC- perteneciente al Observatorio Astronómico Nacional, con sede en Madrid, España. La infraestructura técnica del OAN ha sido tradicionalmente débil y actualmente se está haciendo un esfuerzo por fortalecerla. Existe una información muy limitada del telescopio en general; de su óptica en particular se conocían los valores de los parámetros principales pero sin saber si éstos corresponden a valores teóricos ó de construcción. Por ello se consideró necesario iniciar una investigación para conocer en detalle los valores reales de las componentes ópticas del telescopio, obteniéndose algunos resultados de interés. El primario del telescopio OANl5O es aproximadamente F/3 y el siste ma en su conjunto es F/8.2, con su sistema corrector de campo. En términos generales, la imagen es satisfactoria en todo el campo y, sin sistema corrector, la imagen axial también es buena. En un futuro muy cercano se piensa diseñar instrumentación adicional para este telescopio. Conocer con mayor precisión sus características puede ser de gran utilidad para tal fin, pues se efectúan los cálculos considerando conjuntamente al telescopio y al instrumento.

  4. Los plaguicidas y la contaminacion del medio ambiente Venezolano

    USGS Publications Warehouse

    Stickel, L.F.; Stickel, W.H.

    1972-01-01

    RESUMEN DE RECOMENDACIONES Recomendaciones para el Programa de Investigacion: 1. Establecer un sistema de muestreo biologico para detectar los niveles tendencias de los productos quimicos toxicos en un peque?o numero de si tios representativos. 2. Mantener continua vigilancia de la contaminacion ambiental, mediante la seleccion acertadamente dirigida de las zonas afectadas y de las fuentes de contaminacion. 3. Realizar estudios acerca de las poblaciones de animales silvestres, y del exito de los procesos reproductivos de las especies o grupos clayes de animales que se consideran mas gravemente afectados. 4. Preparar recomendaciones para una accion gubernamental de proteccion al hombre, a la fauna silvestre y al medio ambiente. Recomendaciones para la Accion Administrativa: 1. Establecer limites a la tolerancia de los residuos de plaguicidas en los alimentos. Constituye una medida clave para disminuir la contaminacion ambiental. 2. Establecer normas de calidad del agua para las corrientes, represas, la gos y otros cuerpos. Es la segunda medida clave para reducir la contaminacion del ambiente 3. Exigir un tratamiento adecuado de los efluentes industriales, especialmente antes de que se construyan las nuevas plantas. 4. Exigir a los agricultores que en el uso de plaguicidas sigan los consejos tecnicos autorizados y negar a los vendedores el derecho a recomendar productos por su cuenta. 5. Tomar medidas para recoger y eliminar los recipientes y sobrantes de los plaguicidas.

  5. Field Measurements of Respiratory Del13CO2 and Photodegradation

    NASA Astrophysics Data System (ADS)

    van Asperen, H.; Sabbatini, S.; Nicolini, G.; Warneke, T.; Papale, D.; Notholt, J.

    2014-12-01

    Carbon decomposition dynamics have been studied in a variety of ecosystems and its variation can mostly be explained in terms of environmental variables (e.g. temperature and precipitation). However, carbon dynamics in arid, water limited regions have shown to be very different and are still largely unknown. Several studies have indicated the importance of photodegradation, the direct breakdown of organic matter by sunlight, in these arid regions. A FTIR (Fourier Transform Infrared Spectrometer) was set up to continuously measure concentrations of CO2, CH4, N2O, CO as well as del13C in CO2. The FTIR was connected to 2 different flux measurement systems: a Flux Gradient system and 2 flux chambers, providing a continuous data set of gas concentrations and biosphere-atmosphere gas fluxes at different heights and scales. Field measurements showed photodegradation induced carbon fluxes. Also, respiratory del13CO2 was determined by use of Keeling plots, and was determined to vary between -25‰ and -21‰. A clear diurnal pattern in respiratory del13CO2 was found, suggesting either different (dominant) respiratory processes between day and night or the effect of diffusive fractionation.

  6. Modeling Visibility in the EL Paso del Norte Region

    NASA Astrophysics Data System (ADS)

    Fitzgerald, R. M.; Medina, R.; DuBois, D. W.; Novlan, D.

    2013-12-01

    Poor visibility is a subject of growing public concern throughout the U.S, and an active area of research. Its societal impacts in air quality, aviation transport and traffic are significant. Aerosols play a fundamental role in the attenuation of solar radiation, and also affect visibility. The scattering and extinction coefficients of aerosol particles in the Paso del Norte Region have been calculated using the T- matrix model in conjunction with a laser particle counter. Inter-comparison of the model's results of the scattering and absorption coefficients against the corresponding data from a Photoacustic Extinctiometer instrument (which measures in-situ absorption and scattering coefficients of aerosol particles) shows excellent agreement. In addition, the volume-weighted method is used to determine the composite index of refraction which is representative of the aerosols for the Paso del Norte Airshed to obtain information of the type of aerosol particles present in the Airshed. The Single Scattering Albedo has also been retrieved using our methodology to obtain further insight into the type of aerosols present on a given day. Finally, the Koschmieder equation has been used to calculate the visual range or visibility, and was correlated with the PM2.5 and PM10 particle concentration present in the Airshed. Our methodology will allow a better understanding of the size and type of aerosol particles that are most detrimental to the visibility for the Paso del Norte Region.

  7. Modeling visibility in the Paso del Norte (PDN) Region

    NASA Astrophysics Data System (ADS)

    Medina Calderon, Richard

    Poor visibility is a subject of growing public concern throughout the U.S, and an active area of research. Its societal impacts on air quality, aviation transport and traffic are significant. Aerosols play a fundamental role in the attenuation of solar radiation, and also affect visibility. The scattering and extinction coefficients of aerosol particles in the Paso del Norte Region have been calculated using the T- matrix model in conjunction with a laser particle counter. Inter-comparison of the model's results of the scattering and absorption coefficients against the corresponding data from a Photoacustic extinctiometer instrument (which measures in-situ absorption and scattering coefficients of aerosol particles) shows excellent agreement. In addition, the volume-weighted method is used to determine the composite index of refraction which is representative of the aerosols for the Paso del Norte Region to obtain information of the type of aerosol particles present in the Region. The Single Scattering Albedo has also been retrieved using this methodology to obtain further insight into the type of aerosols present on a given day. Finally, the Koschmieder equation has been used to calculate the visual range or visibility, and was correlated with the PM2.5 and PM10 particle concentration present in the Region. Our methodology will allow a better understanding of the size and type of aerosol particles that are most detrimental to the visibility for the Paso Del Norte Region.

  8. Systemic Functional Linguistics and Discourse Analysis as Alternatives When Dealing with Texts (La lingüística sistémica funcional y el análisis del discurso como alternativas para trabajar con textos)

    ERIC Educational Resources Information Center

    García Montes, Paula Andrea; Sagre Barboza, Ana María; Lacharme Olascoaga, Alba Isabel

    2014-01-01

    This article presents a case study research with aims to find out which activities, methodological and textual aspects used in a reading strategies course were causing a group of students difficulties when analyzing critically written information. We conducted the study at Universidad de Córdoba (Colombia) with seventh semester students from the…

  9. Estrategia innovadora enfocada en parejas del mismo sexo para disminuir la infección del VIH en hombres Latinos

    PubMed Central

    Martinez, Omar; Wu, Elwin; Sandfort, Theo; Shultz, Andrew Z.; Capote, Jonathan; Chávez, Silvia; Moya, Eva; Dodge, Brian; Morales, Gabriel; Porras, Antonio; Ovejero, Hugo

    2014-01-01

    Resumen El VIH es un problema de salud importante dentro de la comunidad latina de los Estados Unidos. Gracias a los esfuerzos de prevención, los niveles de contagio entre los latinos se han mantenido estables por más de una década. Sin embargo, esta población sigue siendo afectada a niveles muy altos, en particular entre hombres que tienen sexo con hombres (HSH), de origen latino y que hablan principalmente el idioma español. Existen varios factores que contribuyen a la transmisión del VIH entre esta población, como son: el uso de drogas; la violencia dentro de la pareja; la presencia de infecciones de transmisión sexual; relaciones sexuales sin protección, dentro y fuera de la pareja; el evadir la búsqueda de recursos (prueba y tratamiento adecuado) por temor a ser discriminado o por su estatus migratorio; la escasez de recursos económicos o estado de pobreza y los patrones relacionados a la migración. En particular, Investigaciones Epidemiológicas de Comportamientos han determinado: cómo algunas dinámicas en parejas están directamente asociadas a los comportamientos sexuales de riesgos. En consecuencia, es necesaria mayor investigación para identificar esas dinámicas, y a su vez, realizar intervenciones dirigidas a la reducción de conductas de riesgo enfocadas en parejas de hombres del mismo sexo. En este escrito, se describe la importancia del uso de las relaciones de pareja como estrategia en la reducción de la trasmisión del VIH/SIDA en HSH de origen latino y que hablan principalmente el idioma español en los Estados Unidos. PMID:25580466

  10. The 2012 Reactivation of Nevado del Ruiz Volcano, Colombia

    NASA Astrophysics Data System (ADS)

    Ordoñez, M.; Lopez, C.; Cortes, G. P.; Londoño, J.; Battaglia, M.

    2012-12-01

    Nevado Del Ruiz volcano is most known for its tragic November 13, 1985 explosive event, when a small eruption produced an enormous lahar that buried and destroyed the town of Armero in Tolima, causing an estimated 25,000 deaths. Similar but less deadly incidents occurred in 1595 and 1845, again where a small explosive eruption was followed by a large lahar. Other minor explosive events occurred in 1805, 1828-9, and 1989. The Armero tragedy was a major factor in the establishment of a volcano monitoring program in Colombia. The network monitoring Nevado del Ruiz volcano has dramatically improved since the 1985 eruption and now includes geodetic, geophysical, geochemical and visual monitoring. The activity of Nevado Del Ruiz between 1985 and 1991 saw significant increases in seismicity and significant gas emissions with the main eruptive events of November 13, 1985 and September 1st, 1989. The volcano became seismically active again in 1995 and 2002, whit an increase in seismicity, without any gas emission or eruption. In October 2010 the volcano entered in a new phase of unrest with increased seismicity (HB events), deformation and gas emissions, likely associated with a new magma intrusion. In February, 2012 the volcano had a new and significant increase in seismicity (VT-LP), followed in May and June 2012 by small phreatic and phreato-magmatic eruption. This eruptive activity is still ongoing. Deformation measurements at Nevado Del Ruiz volcano have been carried out since just after the tragic eruption of the 13th of November 1985. In 2007 seven new electronic tilt meters were set up to monitor the deformation. Significant uplift was measured from August 2007 to October 2010, for a total cumulative value of more than 500 microradians. From the end of 2011 to July 2012, moderate changes of uplift were detected for a total of 70 microradians. The analysis of these deformation data shows a pattern of surface displacement associated with an intrusion of new magma

  11. Perk Ablation Ameliorates Myelination in S63del-Charcot–Marie–Tooth 1B Neuropathy

    PubMed Central

    Musner, Nicolò; Sidoli, Mariapaola; Zambroni, Desireè; Del Carro, Ubaldo; Ungaro, Daniela; D’Antonio, Maurizio; Feltri, Maria L.

    2016-01-01

    In peripheral nerves, P0 glycoprotein accounts for more than 20% of myelin protein content. P0 is synthesized by Schwann cells, processed in the endoplasmic reticulum (ER) and enters the secretory pathway. However, the mutant P0 with S63 deleted (P0S63del) accumulates in the ER lumen and induces a demyelinating neuropathy in Charcot–Marie–Tooth disease type 1B (CMT1B)–S63del mice. Accumulation of P0S63del in the ER triggers a persistent unfolded protein response. Protein kinase RNA-like endoplasmic reticulum kinase (PERK) is an ER stress sensor that phosphorylates eukaryotic initiation factor 2 alpha (eIF2alpha) in order to attenuate protein synthesis. We have shown that increasing phosphophorylated-eIF2alpha (P-eIF2alpha) is a potent therapeutic strategy, improving myelination and motor function in S63del mice. Here, we explore the converse experiment: Perk haploinsufficiency reduces P-eIF2alpha in S63del nerves as expected, but surprisingly, ameliorates, rather than worsens S63del neuropathy. Motor performance and myelin abnormalities improved in S63del//Perk+/− compared with S63del mice. These data suggest that mechanisms other than protein translation might be involved in CMT1B/S63del neuropathy. In addition, Perk deficiency in other cells may contribute to demyelination in a non–Schwann-cell autonomous manner. PMID:27095827

  12. Perk Ablation Ameliorates Myelination in S63del-Charcot-Marie-Tooth 1B Neuropathy.

    PubMed

    Musner, Nicolò; Sidoli, Mariapaola; Zambroni, Desireè; Del Carro, Ubaldo; Ungaro, Daniela; D'Antonio, Maurizio; Feltri, Maria L; Wrabetz, Lawrence

    2016-04-01

    In peripheral nerves, P0 glycoprotein accounts for more than 20% of myelin protein content. P0 is synthesized by Schwann cells, processed in the endoplasmic reticulum (ER) and enters the secretory pathway. However, the mutant P0 with S63 deleted (P0S63del) accumulates in the ER lumen and induces a demyelinating neuropathy in Charcot-Marie-Tooth disease type 1B (CMT1B)-S63del mice. Accumulation of P0S63del in the ER triggers a persistent unfolded protein response. Protein kinase RNA-like endoplasmic reticulum kinase (PERK) is an ER stress sensor that phosphorylates eukaryotic initiation factor 2 alpha (eIF2alpha) in order to attenuate protein synthesis. We have shown that increasing phosphophorylated-eIF2alpha (P-eIF2alpha) is a potent therapeutic strategy, improving myelination and motor function in S63del mice. Here, we explore the converse experiment:Perkhaploinsufficiency reduces P-eIF2alpha in S63del nerves as expected, but surprisingly, ameliorates, rather than worsens S63del neuropathy. Motor performance and myelin abnormalities improved in S63del//Perk+/- compared with S63del mice. These data suggest that mechanisms other than protein translation might be involved in CMT1B/S63del neuropathy. In addition,Perkdeficiency in other cells may contribute to demyelination in a non-Schwann-cell autonomous manner. PMID:27095827

  13. Screening for 185delAG in the Ashkenazim.

    PubMed Central

    Richards, C S; Ward, P A; Roa, B B; Friedman, L C; Boyd, A A; Kuenzli, G; Dunn, J K; Plon, S E

    1997-01-01

    A study was initiated to assess interest, educational effectiveness, and implications of genetic testing for the common BRCA1 mutation, 185delAG, in the Ashkenazim. Of 333 individuals who attended group sessions, 309 (92%) participated in the study. Participants were categorized as having negative family history (67%), positive family history (defined, by a relaxed criterion, as one first-degree relative or two second-degree relatives with breast [premenopausal] or ovarian cancer) (22%), positive personal history (7%), and both positive personal history and positive family history (4%). Group education was effective, as shown by the improvement in participant scores from pre- to posteducation tests. For the 289 individuals (94%) who requested testing, the major reasons included concern for their own risk, concern for the risk of their children, and desire to learn about surveillance options. The most common reason given by participants who declined testing was concern about health insurance. Six participants found to be heterozygous for the 185delAG mutation received results and were offered genetic counseling. Participants had consented for additional testing without receiving results and were screened for the 6174delT mutation in BRCA2, and seven were found to be positive. All identified carriers reported at least one first- or second-degree relative with a history of breast or ovarian cancer, although they did not all meet our study criteria for positive family history. Given these outcomes, we conclude that screening for breast and ovarian cancer susceptibility is most appropriate for individuals with a positive personal or positive family cancer history. We propose a guideline for future studies designed to identify individuals who may benefit from genetic testing for inherited breast and ovarian cancer. Images Figure 1 PMID:9150156

  14. Optical photometry and spectroscopy of Nova Del 2013

    NASA Astrophysics Data System (ADS)

    Tomov, T.; Ilkiewicz, K.; Swierczynski, E.; Belcheva, M.; Dimitrov, D.

    2013-08-01

    We report optical BV photometry and spectroscopy of Nova Del 2013, carried out between August 14.88 UT and August 15.08 UT. Using a 60 cm Cassegrain telescope at the Nicolaus Copernicus University Observatory (Torun, Poland) we estimated the V brightness of the Nova to be 6.31+/-0.02 mag and 6.18+/-0.03 mag on Aug. 14.94 UT and Aug. 15.02 UT respectively. HD 194113 (F2, V=8.00 mag) was used as a comparison star.

  15. Stray-light measurements at the Observatorio del Teide

    NASA Astrophysics Data System (ADS)

    Martinez Pillet, V.; Ruiz Cobo, B.; Vázquez, M.

    1990-09-01

    A new procedure to separate the instrumental and atmospheric components of stray light is presented. It is based on the dependence of the aureole's atmospheric component on the air mass and is applied to measurements taken with the Vacuum Newton Telescope (VNT) at the Observatorio del Teide (Tenerife). The resulting instrumental part is independent of the air mass. The variation of both components with wavelength is also studied. The instrumental component shows no dependence on wavelength, in contrast to the atmospheric one which is greater in the blue than in the red. It is concluded that observations with air masses larger than two will probably be strongly affected by stray light.

  16. Stray-light measurements at the Observatorio del Teide

    NASA Astrophysics Data System (ADS)

    Martinez Pillet, V.; Ruiz Cobo, B.; Vazquez, M.

    1990-02-01

    A new procedure to separate the instrumental and atmospheric components of stray light is presented. It is based on the dependence of the aureole's atmospheric component on the air mass and is applied to measurements taken with the Vacuum Newton Telescope (VNT) at the Observatorio del Teide (Tenerife). The resulting instrumental part is independent of the air mass. The variation of both components with wavelength is also studied. The instrumental component shows no dependence on wavelength, in contrast to the atmospheric one which is greater in the blue than in the red. It is concluded that observations with air masses larger than two will probably be strongly affected by stray light.

  17. Medical ethnobotany of the Teribes of Bocas del Toro, Panama.

    PubMed

    Gupta, M P; Solís, P N; Calderón, A I; Guionneau-Sinclair, F; Guinneau-Sinclair, F; Correa, M; Galdames, C; Guerra, C; Espinosa, A; Alvenda, G I; Robles, G; Ocampo, R

    2005-01-15

    Ethnomedical uses of 108 medicinal plant species, belonging to 52 families, 89 genera, used by the Teribe Amerindians of Bocas del Toro Province in Panama, along with their socio-cultural practices are reported here. The methods of administration of the herbal remedies, the plant parts used, their families and local names are also documented. The recorded medicinal plants were used mainly for fever, various type of pain and inflammation. The potential value of 26 plants and their traditional uses was elucidated through literature search. PMID:15619557

  18. 33 CFR 162.200 - Marina del Rey, Calif.; restricted area.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Marina del Rey, Calif.; restricted area. 162.200 Section 162.200 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY INLAND WATERWAYS NAVIGATION REGULATIONS § 162.200 Marina del Rey, Calif.; restricted area. (a)...

  19. [Recommendations to improve the scientific communication process in the Revista Médica del IMSS].

    PubMed

    Álvarez, Ivón

    2016-01-01

    In order to improve the position of the Revista Médica del Instituto Mexicano del Seguro Social among the different journals, in this editorial we enumerate a series of recommendations to ameliorate the practices of the different actors who participate in the scientific communication process of this journal. PMID:26820191

  20. 33 CFR 162.200 - Marina del Rey, Calif.; restricted area.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Marina del Rey, Calif.; restricted area. 162.200 Section 162.200 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY INLAND WATERWAYS NAVIGATION REGULATIONS § 162.200 Marina del Rey, Calif.; restricted area. (a)...

  1. 62. R.L.T., photographer November 1, 1934 DEL NORTE COUNTY, SECTION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    62. R.L.T., photographer November 1, 1934 DEL NORTE COUNTY, SECTION D, HIGHWAY 1. REDWOOD CLEARING ON EXISTING LINE, 1-DN-71-A #26, R.L.T. 11-1-34. Stamped office copy. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  2. 63. G.F.H., photographer July 30, 1932 DEL NORTE COUNTY, SECTION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    63. G.F.H., photographer July 30, 1932 DEL NORTE COUNTY, SECTION A, HIGHWAY 1. 1-DN A #124, STA. 164=00 SHOWING DRAINAGE CONDITIONS, G.F.H., 7-30-32. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  3. 33 CFR 334.110 - Delaware Bay off Cape Henlopen, Del.; naval restricted area.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., Del.; naval restricted area. 334.110 Section 334.110 Navigation and Navigable Waters CORPS OF....110 Delaware Bay off Cape Henlopen, Del.; naval restricted area. (a) The area. Beginning at a point on... regulations in this section shall be enforced by the Commandant, Fourth Naval District, and such agencies...

  4. 33 CFR 334.110 - Delaware Bay off Cape Henlopen, Del.; naval restricted area.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., Del.; naval restricted area. 334.110 Section 334.110 Navigation and Navigable Waters CORPS OF....110 Delaware Bay off Cape Henlopen, Del.; naval restricted area. (a) The area. Beginning at a point on... regulations in this section shall be enforced by the Commandant, Fourth Naval District, and such agencies...

  5. Statistical Comparisons of Pre and Post Del Mod Data, Final Report, Volume V.

    ERIC Educational Resources Information Center

    Bolig, John R.; Wall, Charles A.

    This is one of five volumes prepared to describe various aspects of the Del Mod System. This report attempts to compare baseline data gathered in 1970-71 to post experimental data gathered in 1975-76. Sections include analyses of achievement test scores, research conducted under the auspices of the Del Mod System, and a follow-up study of…

  6. 66. Photographer unknown March 1920'S DEL NORTE COUNTY, SECTION B, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    66. Photographer unknown March 1920'S DEL NORTE COUNTY, SECTION B, HIGHWAY 1. 1-DN 1-B #9, CORDUROY DETOUR INTO CRESCENT CITY, 2-2 (3?). Stamped office copy. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  7. 33 CFR 162.200 - Marina del Rey, Calif.; restricted area.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Marina del Rey, Calif.; restricted area. 162.200 Section 162.200 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY INLAND WATERWAYS NAVIGATION REGULATIONS § 162.200 Marina del Rey, Calif.; restricted area. (a)...

  8. Late Quaternary vegetation and climate of southern Tierra del Fuego

    NASA Astrophysics Data System (ADS)

    Heusser, Calvin J.

    1989-05-01

    Vegetation and climate over approximately the past 13,000 yr are reconstructed from fossil pollen in a 9.4-m mire section at Caleta Róbalo on Beagle Channel, Isla Navarino (54°56'S, 67°38'W), southern Tierra del Fuego. Fifty surface samples reflecting modern pollen dispersal serve to interpret the record. Chronologically controlled by nine radiocarbon dates, fossil pollen assemblages are: Empetrum-Gramineae- Gunnera-Tubuliflorae (zone 3b, 13,000-11,850 yr B.P.), Gramineae- Empetrum-assorted minor taxa (zone 3a, 11,850-10,000 yr B.P.), Nothofagus-Gramineae-Tubuliflorae-Polypodiaceae (zone 2, 10,000-5000 yr B.P.), Nothofagus-Empetrum (zone 1b, 5000-3000 yr B.P.), and Empetrum-Nothofagus (zone 1a, 3000-0 yr B.P.). Assemblages show tundra under a cold, dry climate (zone 3), followed by open woodland (zone 2), as conditions became warmer and less dry, and later, with greater humidity and lower temperatures, by closed forest and the spread of mires (zone 1). Comparisons drawn with records from Antarctica, New Zealand, Tasmania, and the subantarctic islands demonstrate broadly uniform conditions in the circumpolar Southern Hemisphere. The influences of continental and maritime antarctic air masses were apparently considerable in Tierra del Fuego during cold late-glacial time, whereas Holocene climate was largely regulated by interplay between maritime polar and maritime tropical air.

  9. Efecto del Programa de Entrenamiento “Manejo del Dolor” en la Documentación de Enfermería en el Expediente Electrónico

    PubMed Central

    Monsiváis, María Guadalupe Moreno; Guzmán, Ma. Guadalupe Interial; Flores, Paz Francisco Sauceda; Arreola, Leticia Vázquez

    2012-01-01

    Resumen En el presente trabajo se muestra la importancia de entrenar al personal de enfermería para mejorar la documentación en el expediente electrónico. Se eligió el manejo del dolor por ser un área prioritaria; una alta proporción de pacientes en período post operatorio cursa con dolor, por lo tanto, la documentación debe ser útil para la toma de decisiones clínicas. Se implementó un programa de entrenamiento denominado “Manejo del Dolor” dirigido al personal de enfermería. Se utilizó la tecnología de la información como herramienta para fortalecer el conocimiento con base en la revisión sistemática de la literatura; el personal de enfermería participante seleccionó la mejor evidencia; posteriormente se trabajó en la transferencia de este conocimiento a la práctica a través del diseño de un protocolo para el manejo del dolor. Se concluye que el conocimiento del manejo del dolor es fundamental para que enfermería documente con mayor precisión sus intervenciones. PMID:24199106

  10. Disruption of cytokeratin-8 interaction with F508del-CFTR corrects its functional defect

    PubMed Central

    Colas, Julien; Faure, Grazyna; Saussereau, Emilie; Trudel, Stéphanie; Rabeh, Wael M.; Bitam, Sara; Guerrera, Ida Chiara; Fritsch, Janine; Sermet-Gaudelus, Isabelle; Davezac, Noëlie; Brouillard, Franck; Lukacs, Gergely L.; Herrmann, Harald; Ollero, Mario; Edelman, Aleksander

    2012-01-01

    We have previously reported an increased expression of cytokeratins 8/18 (K8/K18) in cells expressing the F508del mutation of cystic fibrosis transmembrane conductance regulator (CFTR). This is associated with increased colocalization of CFTR and K18 in the vicinity of the endoplasmic reticulum, although this is reversed by treating cells with curcumin, resulting in the rescue of F508del-CFTR. In the present work, we hypothesized that (i) the K8/K18 network may interact physically with CFTR, and that (ii) this interaction may modify CFTR function. CFTR was immunoprecipitated from HeLa cells transfected with either wild-type (WT) CFTR or F508del-CFTR. Precipitates were subjected to 2D-gel electrophoresis and differential spots identified by mass spectrometry. K8 and K18 were found significantly increased in F508del-CFTR precipitates. Using surface plasmon resonance, we demonstrate that K8, but not K18, binds directly and preferentially to the F508del over the WT human NBD1 (nucleotide-binding domain-1). In vivo K8 interaction with F508del-CFTR was confirmed by proximity ligation assay in HeLa cells and in primary cultures of human respiratory epithelial cells. Ablation of K8 expression by siRNA in F508del-expressing HeLa cells led to the recovery of CFTR-dependent iodide efflux. Moreover, F508del-expressing mice topically treated with K8-siRNA showed restored nasal potential difference, equivalent to that of WT mice. These results show that disruption of F508del-CFTR and K8 interaction leads to the correction of the F508del-CFTR processing defect, suggesting a novel potential therapeutic target in CF. PMID:22038833

  11. Assessing Glacier Hazards At Ghiacciaio Del Belvedere, Macugnaga, Italian Alps

    NASA Astrophysics Data System (ADS)

    Haeberli, W.; Chiarle, M.; Mortara, G.; Mazza, A.

    The uppermost section of the Valle Anzasca behind and above the community of Macugnaga in the Italian Alps is one of the most spectacular high-mountain land- scapes in Europe, with gigantic rock walls and numerous steep hanging glaciers. Its main glacier, Ghiacciaio del Belvedere at the foot of the huge Monte Rosa east face, is a heavily debris-covered glacier flowing on a thick sediment bed. Problems with floods, avalanches and debris flows from this ice body have been known for extended time periods. Most recently, however, the evolution of this highly dynamic environ- ment has become more dramatic. An outburst of Lago delle Locce, an ice-dammed lake at the confluenec of the tributary Ghiacciaio delle Locce with Ghiacciaio del Belvedere, caused heavy damage in 1979 and necessitated site investigation and con- struction work to be done for flood protection. The intermittent glacier growth ten- dency in the 1970es induced strong bulging of the glacier surface and, in places, caused the glacier tongue to override historical morains and to destroy newly-grown forest stands. A surge-type flow acceleration started in the lower parts of the Monte- Rosa east face during summer 2000, leading to strong crevassing and deformation of Ghiacciaio del Belvedere and extreme bulging of its orographic right margin. High water pressure and accelerated movement lasted into winter 2001/2002: the ice now started overriding the LIA moraine near Rifugio Zamboni of the CAI. In addition but rather independently, a most active detachment zone for rock falls and debris flows developed for several years now in the east face of Monte Rosa, somewhat more to the south of the accelerated glacier movement and at an altitude where relatively warm permafrost must be expected. Besides the scientific interest in these phenomena, the growing hazard potential to the local infrastructure must be considered seriously. Es- pecially potentials for the destabilization of large rock and ice masses in the

  12. [History of Instituto Nacional de Salud Ocupacional del Peru].

    PubMed

    Cossio-Brazzan, Juan M

    2012-06-01

    In Peru, the industry's development has made economic improvements but at the same time, it has had a major impact on the health of the workers; for that reason, it was necessary to generate control mechanisms. So, in 1940 it was created the Departmento de Higiene Industrial, which in 1956 was changed to Instituto de Salud Ocupacional, but it was deactivated in 1994. However, in 2001 it reappeared into the Ministerio de Salud organizational structure with the name of Instituto de Salud Ocupacional "Alberto Hurtado Abadía". Actually, it is the Centro Nacional de Salud Ocupacional y Protección del Ambiente para la Salud (CENSOPAS), organ of the Instituto Nacional de Salud which continues working in synergy with other institutions and sectors, making research to protect the health of exposed persons (workers and community) to contamination and risks associated with economic activities. PMID:22858781

  13. Energy integrated farm system: Del Valle Hog Farm

    SciTech Connect

    Not Available

    1984-01-01

    The Del Valle Hog Farm, a Texas hog farm with grain crops, is designed to conserve energy through methane generation, alcohol production, and efficient use of electrical energy. The integrated energy concepts to be demonstrated are: methane generation from swine manure to produce electricity and heat for alcohol fermentation and distillation and to produce hot water for heating the digester reactors and the hog feeding pens; and alcohol production from milo and distillation of 170 proof alcohol by use of methane and generated electricity. Specific energy technologies to be implemented are: anaerobic digester; gas compressors to store methane for peak demands; engine generator powered by methane; waste-heat exchanger on engine generator to produce hot water; continuous-process alcohol facility to produce 24 gal/day; and crop management.

  14. Circular structures of Bajada del Diablo (Argentina): geophysical signatures

    NASA Astrophysics Data System (ADS)

    Prezzi, C. B.; Orgeira, M. J.; Martinez, O.; Acevedo, R. D.; Ponce, F.; Goldmann, G.; Magneres, I.; Rabassa, J.

    2016-02-01

    Bajada del Diablo is located in the Northern Patagonian Massif, Chubut, Argentina. The study area includes several circular structures found in Miocene olivine basalts of the Quiñelaf Eruptive Complex and in the Late Pliocene/Early Pleistocene Pampa Sastre conglomerates. An impact origin has been proposed for these circular structures. With the aim of further investigate the proposed impact origin, topographic, gravimetric, magnetic, resistivity, paleomagnetic and electromagnetic surveys in two circular structures ("8" and "G") located in Pampa Sastre conglomerates and in basalts of the Quiñelaf Eruptive Complex were carried out. The new geophysical results support the hypothesis of an impact origin. However, the confirmation of such an origin through the findings of shock metamorphism evidences and/or the recovery of meteorites remains elusive.

  15. Renewable energy load assessment for Boquillas Del Carmen Coahuila, Mexico

    SciTech Connect

    Foster, R.

    1995-08-01

    This report outlines the estimates that were made in 1992 of the potential load requirements for Boquillas del Carmen, a small Mexican village on the northern border of the state of Coahuila, Mexico near Big Bend National Park in southern Texas. The study was made to help determine the possibility that village might be electrified by solar or wind energy. Various estimates of are given of the potential load based on estimates ranging from basic use of lights, radio, television, and small household appliances to microwave ovens, refrigerators, and direct evaporative coolers. The low-energy consumption case was estimated to be at 23.0 kWh/month per residence per month, and the high-energy consumption case (with cooling) was 140.7 kWh/month per residence. On average, the typical residence is occupied by five individuals.

  16. Circular structures of Bajada del Diablo (Argentina): geophysical signatures

    NASA Astrophysics Data System (ADS)

    Prezzi, C. B.; Orgeira, M. J.; Martinez, O.; Acevedo, R. D.; Ponce, F.; Goldmann, G.; Magneres, I.; Rabassa, J.

    2016-05-01

    Bajada del Diablo is located in the Northern Patagonian Massif, Chubut, Argentina. The study area includes several circular structures found in Miocene olivine basalts of the Quiñelaf Eruptive Complex and in the Late Pliocene/Early Pleistocene Pampa Sastre conglomerates. An impact origin has been proposed for these circular structures. With the aim of further investigate the proposed impact origin, topographic, gravimetric, magnetic, resistivity, palaeomagnetic and electromagnetic surveys in two circular structures (`8' and `G') located in Pampa Sastre conglomerates and in basalts of the Quiñelaf Eruptive Complex were carried out. The new geophysical results support the hypothesis of an impact origin. However, the confirmation of such an origin through the findings of shock metamorphism evidences and/or the recovery of meteorites remains elusive.

  17. Phytoseiid mites (Acari: Phytoseiidae) from Patagonia and Tierra del Fuego.

    PubMed

    Ferragut, Francisco; Navia, Denise

    2015-01-01

    Predatory phytoseiid mites have been intensively studied and surveyed in the last decades because of their economic importance as biocontrol agents of agricultural pests. However, many regions of the world remain unexplored and the diversity of the family worldwide is still fragmentary. Up to date no phytoseiid species have been collected in the southernmost part of the Earth down to latitude 45º S. In this study Phytoseiidae were sampled from native vegetation in southern Argentina and Chile in the regions of Patagonia and Tierra del Fuego Island. Thirteen species were collected, five of which were previously described and eight, Chileseius australis n. sp., Neoseiulus mapuche n. sp., Typhlodromips valdivianus n. sp., T. fissuratus n. sp., Amblyseius grandiporus n. sp., A. caliginosus n. sp., Typhlodromus (Anthoseius) anomalos n. sp. and Metaseiulus parabrevicollis n. sp. are proposed as new to science and are described and diagnosed. PMID:26250248

  18. Ozone studies in the Paso del Norte region

    NASA Astrophysics Data System (ADS)

    Becerra-Davila, Fernando

    The Paso del Norte region forms the largest contiguous bi-national conglomerate on the US-Mexico border. With a combined population of around 2 million inhabitants, the Paso del Norte region is isolated, more than 500 km away from the nearest urban area of comparable size, thus making it an ideal location for air quality studies of an isolated urban environment. The meteorological conditions leading to a high ozone episode in this region, such as the historical ozone episode of June 2006, are analyzed. It is well known that stagnation and minimal winds, high temperatures, and pressure ridges over the region are conducive to high ozone episodes. In addition, the planetary boundary height is studied to understand its impact on high ozone episodes. Several studies report that ground level ozone non-attainment regulations could be caused not only by local emissions, but also by atmospheric transport. In this work the atmospheric advection of pollutants into the region is analyzed using HYSPLIT backward trajectories. Furthermore, a novel backward trajectory clustering technique is implemented for the summer of 2006. The "ozone weekend effect" (OWE) is a phenomenon by which in some geographical regions ambient ozone concentrations tend to be higher on weekends than on weekdays, despite the lower emissions of ozone precursors during those days. The observed local OWE has never previously been studied in terms of the photolysis rates of four of the main ozone precursors. In this research a novel method that allows the calculation of actinic fluxes, photolysis frequencies and photolysis rates with a high degree of accuracy and reliability has been developed. This method utilizes a combination of the experimental data available for this region in conjunction with a radiative transfer model (TUV model). Three weekend-weekday cases during summers 2006, 2009 and 2010 are studied in this work. In this research, the photolysis impact on the local OWE is studied. The results

  19. Clean cities: Award winning coalition -- Paso del Norte

    SciTech Connect

    O'Connor, K.

    1999-10-25

    Designated the 41st Clean Cities coalition in November 1995, the Paso del Norte Clean Cities Coalition (PDNCCC) is the first in the country to gain international participation. Spanning the US-Mexico border; the coalition includes stakeholders from El Paso, Texas; Ciudad Juarez, Mexico; and Las Cruces, New Mexico. PDNCCC developed a comprehensive plan to jump-start its program place, alternative fuel vehicles (AFVs) on the road, and eliminate barriers inhibiting alternative fuel market growth. PDNCC raised more than $2.3 million for alternative fuel activities and clean air initiatives in less than 26 months. In 1998, the US Department of Energy (DOE) recognized that PDNCCC accomplishment with its Rainmaker Award for leveraging the most funds from outside sources. PDNCCC is proud of its efforts to drive the alternative fuels and AFV market in the El Paso/Juarez region.

  20. Spatially Controlled Fe Isotope Variations at Torres del Paine

    NASA Astrophysics Data System (ADS)

    Gajos, N.; Lundstrom, C.

    2013-12-01

    Recent advances in mass-spectrometry have identified systematic trends of non-traditional stable isotope variation in igneous rocks with differentiation index. We present new Fe isotope data for the Torres del Paine igneous complex in southern Chile. The multi-composition pluton consists of a 1 km vertical exposure of homogenous granite overlying a contemporaneous and possibly cogenetic 0.5 km mafic gabbro suite. Whereas previous isotopic investigations do little to address variations across important magmatic contacts, this study focuses on a first-of-its-kind spatially dependent non-traditional stable isotope investigation of an igneous pluton. Samples were collected at Torres del Paine in spatially significant transects, focusing on major contacts between country rock, granite and mafic units. Results collected by bracketed double spike MC-ICP-MS (2s precision of ×0.03) show an increase in δ56Fe towards the high silica margins of the pluton with values as high as δ56Fe 0.36. Additionally, the data show a decrease in δ56Fe toward the mafic center of the pluton with δ56Fe values ranging from δ56Fe -0.05 to 0.18. Samples collected on the contact between the granite and mafic complex show intermediate values of δ56Fe= 0.18(×) 0.03. Country rock samples in contact with granite show an isotopically light signature of δ56Fe=0.04 (×) 0.03. Analysis of 50 samples in total show a trend of increasing δ56Fe with SiO2 content. The process responsible for Fe isotope variations remains debated but is suggested to reflect four mechanisms: (1) crustal assimilation, (2) fractional crystallization, (3) late stage fluid exsolution [1] and (4) thermal migration [3]. Preliminary results show that mechanisms #1 and #2 would produce isotopic signatures opposite of those seen at Torres del Paine and other plutonic rocks. Isotopically light Torres country rock samples reveal that assimilation of rocks would not produce the isotopically heavy granites seen at Torres. Based on

  1. DEL-1 restrains osteoclastogenesis and inhibits inflammatory bone loss in nonhuman primates.

    PubMed

    Shin, Jieun; Maekawa, Tomoki; Abe, Toshiharu; Hajishengallis, Evlambia; Hosur, Kavita; Pyaram, Kalyani; Mitroulis, Ioannis; Chavakis, Triantafyllos; Hajishengallis, George

    2015-09-30

    DEL-1 (developmental endothelial locus-1) is an endothelial cell-secreted protein that regulates LFA-1 (lymphocyte function-associated antigen-1) integrin-dependent leukocyte recruitment and inflammation in various tissues. We identified a novel regulatory mechanism of DEL-1 in osteoclast biology. Specifically, we showed that DEL-1 is expressed by human and mouse osteoclasts and regulates their differentiation and resorptive function. Mechanistically, DEL-1 inhibited the expression of NFATc1, a master regulator of osteoclastogenesis, in a Mac-1 integrin-dependent manner. In vivo mechanistic analysis has dissociated the anti-inflammatory from the anti-bone-resorptive action of DEL-1 and identified structural components thereof mediating these distinct functions. Locally administered human DEL-1 blocked inflammatory periodontal bone loss in nonhuman primates-a relevant model of human periodontitis. The ability of DEL-1 to regulate both upstream (inflammatory cell recruitment) and downstream (osteoclastogenesis) events that lead to inflammatory bone loss paves the way to a new class of endogenous therapeutics for treating periodontitis and perhaps other inflammatory disorders. PMID:26424570

  2. Deglacial palaeoclimate at Puerto del Hambre, subantarctic Patagonia, Chile

    NASA Astrophysics Data System (ADS)

    Heusser, Calvin J.; Heusser, Linda E.; Lowell, Thomas V.; Moreira M., Andrés; Moreira M., Simón

    2000-02-01

    The primary objective of this study is to further substantiate multistep climatic forcing of late-glacial vegetation in southern South America. A secondary objective is to establish the age of deglaciation in Estrecho de Magallanes-Bahía Inútil. Pollen assemblages at 2-cm intervals in a core of the mire at Puerto del Hambre (53°3621S, 70°5553W) provide the basis for reconstructing the vegetation and a detailed account of palaeoclimate in subantarctic Patagonia. Chronology over the 262-cm length of core is regulated by 20 AMS radiocarbon dates between 14 455 and 10 089 14C yr BP. Of 13 pollen assemblage zones, the earliest representing the Oldest Dryas chronozone (14 455-13 000 14C yr BP) records impoverished steppe with decreasing frequencies and loss of southern beech (Nothofagus). Successive 100-yr-long episodes of grass/herbs and of heath (Empetrum/Ericaceae) before 14 000 14C yr BP infer deglacial successional communities under a climate of increased continentality prior to the establishment of grass-dominated steppe. The Bølling-Allerød (13 000-11 000 14C yr BP) is characterised by mesic grassland under moderating climate that with abrupt change to heath dominance after 12 000 14C yr BP was warmer and not as humid. At the time of the Younger Dryas (11 000-10 000 14C yr BP), grass steppe expanded with a return of colder, more humid climate. Later, with gradual warming, communities were invaded by southern beech. The Puerto del Hambre record parallels multistep, deglacial palaeoclimatic sequences reported elsewhere in the Southern Andes and at Taylor Dome in Antarctica. Deglaciation of Estrecho de Magallanes-Bahía Inútil is dated close to 14 455 14C yr BP, invalidating earlier dates of between 15 800 and 16 590 14C yr BP.

  3. [Epidemiology of dog bite lesions in Tierra del Fuego, Argentina].

    PubMed

    Zanini, Fabián; Padinger, Patricia; Elissondo, María C; Pérez, Héctor

    2008-01-01

    The coexistence between man and dog has resulted in mutual benefits during thousands of years, nevertheless some problems have recently arisen where bite injuries have an important role. The aim of this work was to describe the epidemiological characteristics of dog bite lesions which occurred during a year in Tierra del Fuego. A descriptive observational, transversal study of patients who were admitted with dog bite injuries to clinic and pediatric emergency services of hospitals and health centers was carried out between 3/1/05 and 3/1/06. A total of 382 records were made. The children group represents 49.5%. The group between 5 and 9 year-old was the most affected (44.4%; IC95% 37.2-51.8). In the adult group, that between 15 and 24 year-old was the most affected (29.5%; IC95% 23.2-36.5). More lesions were registered in men (57.6%) than in women (42.4%) (chi2 = 8.6, p = 0.003). During spring and summer months, 56.5% of the lesions were registered. A 72.8% of the incidents occurred on the public highway. Dogs of big size were responsible of 49.7% (IC95% 44.6-54.9) of the injuries. The 89.8% of the incidents were caused by another person's dog. Of the lesions, 55.8% (IC95% 50.6-60.8) were registered in lower extremities and 11% (IC95% 8.1-14.7) in head and neck. These data show that dog bite lesions affect the health and impact in the quality of life of the population of Tierra del Fuego, Argentina. PMID:18416313

  4. Spatial shell structure of the novas DQ Her and HR Del

    SciTech Connect

    Pilyogin, L.S.

    1986-03-01

    This paper considers the formation of the spatial shell structure of the novas DQ Her (1934) and HR Del (1967). It is shown that the existence of polar caps is due to the influence of the second component of the system on the angular distribution of the mass shell depth of the mainshell. The ratio of the mass shell depth in the equatorial ring and in the polar caps is 1.13 for DQ Her and 2.7 for HR Del. The ratio of the maximal densities in the equatorial ring and the polar caps is of order 3 for DQ Her and of order 70 for HR Del.

  5. General nonextremal rotating charged Gödel black holes in minimal five-dimensional gauged supergravity.

    PubMed

    Wu, Shuang-Qing

    2008-03-28

    I present the general exact solutions for nonextremal rotating charged black holes in the Gödel universe of five-dimensional minimal supergravity theory. They are uniquely characterized by four nontrivial parameters: namely, the mass m, the charge q, the Kerr equal rotation parameter a, and the Gödel parameter j. I calculate the conserved energy, angular momenta, and charge for the solutions and show that they completely satisfy the first law of black hole thermodynamics. I also study the symmetry and separability of the Hamilton-Jacobi and the massive Klein-Gordon equations in these Einstein-Maxwell-Chern-Simons-Gödel black hole backgrounds. PMID:18517852

  6. General Nonextremal Rotating Charged Gödel Black Holes in Minimal Five-Dimensional Gauged Supergravity

    NASA Astrophysics Data System (ADS)

    Wu, Shuang-Qing

    2008-03-01

    I present the general exact solutions for nonextremal rotating charged black holes in the Gödel universe of five-dimensional minimal supergravity theory. They are uniquely characterized by four nontrivial parameters: namely, the mass m, the charge q, the Kerr equal rotation parameter a, and the Gödel parameter j. I calculate the conserved energy, angular momenta, and charge for the solutions and show that they completely satisfy the first law of black hole thermodynamics. I also study the symmetry and separability of the Hamilton-Jacobi and the massive Klein-Gordon equations in these Einstein-Maxwell-Chern-Simons-Gödel black hole backgrounds.

  7. Resultados del relevamiento de HI en el Cielo Austral: 3. Relevamiento de Nubes de Alta Velocidad

    NASA Astrophysics Data System (ADS)

    Morras, R.; Bajaja, E.; Arnal, E. M.; Pöppel, W. G. L.

    Los resultados del relevamiento de HI del Hemisferio Austral fueron reprocesados con el fin de incrementar su sensibilidad. Así, se utilizó esta nueva base de datos con el fin de obtener un nuevo relevamiento de Nubes de Alta Velocidad en el cielo austral. El ruido r.m.s. alcanzado es de 0.015-0.020 K, con una resolución espectral de 8 km/seg. El cubrimiento espacial del relevamiento mejora en un factor 16 al realizado por Bajaja et al (1985).

  8. HAER DEL,3MILF.V,2 (sheet 1 of 4) Mispillion Lighthouse, South ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    HAER DEL,3-MILF.V,2- (sheet 1 of 4) - Mispillion Lighthouse, South bank of Mispillion River at its confluence with Delaware River at northeast end of County Road 203, 7 miles east of Milford, Milford, Sussex County, DE

  9. HAER DEL,3MILF.V,2 (sheet 2 of 4) Mispillion Lighthouse, South ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    HAER DEL,3-MILF.V,2- (sheet 2 of 4) - Mispillion Lighthouse, South bank of Mispillion River at its confluence with Delaware River at northeast end of County Road 203, 7 miles east of Milford, Milford, Sussex County, DE

  10. HAER DEL,3MILF.V,2 (sheet 3 of 4) Mispillion Lighthouse, South ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    HAER DEL,3-MILF.V,2- (sheet 3 of 4) - Mispillion Lighthouse, South bank of Mispillion River at its confluence with Delaware River at northeast end of County Road 203, 7 miles east of Milford, Milford, Sussex County, DE

  11. HAER DEL,3MILF.V,2 (sheet 4 of 4) Mispillion Lighthouse, South ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    HAER DEL,3-MILF.V,2- (sheet 4 of 4) - Mispillion Lighthouse, South bank of Mispillion River at its confluence with Delaware River at northeast end of County Road 203, 7 miles east of Milford, Milford, Sussex County, DE

  12. [Progress in InDel as a new generation of genetic marker].

    PubMed

    Sun, Kuan; Zhang, Su-Hua; Zhu, Ru-Xin; Zhao, Shu-Min; Li, Cheng-Tao

    2013-04-01

    As forensic DNA typing experienced three generations of genetic marker researching stage, short tandem repeat (STR) has been widely used in forensic identification as a mature tool. Further exploration of the human genome led to the discovery of polymorphism markers of single nucleotide polymorphism (SNP) and Insertion/Deletion (InDel). InDel, which combines the desirable characteristics of previous genetic markers as a new type of genetic marker, has got extensive concern in fields like medical molecular biology and forensic biology. This paper generally reviews the history of research and the corresponding results of InDel along the line of time axis as well as the different aims of these research focusing on the progress in the multiple amplification system with several InDel as the genetic marker (autosomal or X chromosome) in forensic biology and anthropology. Finally, the direction of research in this field and the problems to be solved have been put forward. PMID:23930511

  13. Three cases of dup(10p)/del(10q) syndrome resulting from maternal pericentric inversion.

    PubMed

    Kulharya, A S; Schneider, N R; Wilson, G N

    1993-11-01

    Two families and 3 patients with dup(10p)/del(10q) syndrome segregating from a maternal pericentric inversion are described, including a stillborn female with Potter sequence and multicystic renal dysplasia. Comparison of 32 dup(10p) patients to 11 del(10)(q25) patients emphasized dolichocephaly, wide sutures, frontal bossing, micrognathia, and renal defects as distinguishing characteristics of the dup(10p) syndrome. The 3 new and 6 previously reported dup(10p)/del(10q) patients had several manifestations in common with the dup(10p) and del(10q) syndromes, but were more typical of dup(10p) syndrome with respect to all 5 distinguishing characters. PMID:8279477

  14. 90. Paso Del Norte Hotel, 115117 South El Paso St.,east ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    90. Paso Del Norte Hotel, 115-117 South El Paso St.,east facade, west side of street - South El Paso Street Historic District, South El Paso, South Oregon & South Santa Fe Streets, El Paso, El Paso County, TX

  15. The extracellular matrix protein Del1 induces apoptosis via its epidermal growth factor motif.

    PubMed

    Kitano, Hisataka; Kokubun, Shinichiro; Hidai, Chiaki

    2010-03-19

    Mouse Del1 is an extracellular matrix protein mainly expressed in the developing embryo. Del1 has three EGF motifs and two discoidin domains. The second EGF motif reportedly contains an RGD sequence that binds to integrin receptors. Here, we provide evidence that Del1 protein induces cell death in vitro. Chromatin condensation and DNA laddering were observed, suggestive of apoptosis. The results of analysis using the TUNEL method and annexin V staining were also consistent with apoptosis. The apoptosis-inducing activity of Del1 could be mapped to the third EGF motif, which fitted the consensus sequence CX(D/N)XXXX(F/Y)XCXC, wherein the aspartic acid residue (D) could be beta-hydroxylated. As little as twenty-five picomolar of recombinant E3 could induce apoptosis. PMID:20171188

  16. Impact of Observing Parameters on 17 Nights with Nova Del 2013 (Abstract)

    NASA Astrophysics Data System (ADS)

    Green, W. L.

    2014-12-01

    (Abstract only) Nova Del 2013 (V339 Del) was reported in Astronomer’s Telegram No. 5279 (PNV 20233073+2046041) on 2013 August 14. On the following day, the University of Colorado, Boulder, granted our observing request for use of the R3000-5000 spectrograph attached to their 60-cm telescope. The planning, operational approach, analysis techniques, results, issues, and operational conclusions for data taken from 15 August through 2 September are reported here.

  17. Defining the defect in F508 del CFTR: a soluble problem?

    PubMed

    Deber, Charles M; Cheung, Joanne C; Rath, Arianna

    2008-01-01

    Previously reported crystal structures of CFTR F508 del-NBD1 were determined in the presence of solubilizing mutations. In this issue of Chemistry & Biology, Pissarra et al. (2008) show that partial rescue of the trafficking and gating defects of full-length CFTR occurs in vivo upon recapitulation of the solubilizing F494N/Q637R or F428S/F494N/Q637R substitutions in cis with F508 del. PMID:18215767

  18. RASTREO DEL CANCER COLORRECTAL CONOCIMIENTO Y ACTITUD DE LA POBLACION

    PubMed Central

    CASAL, ENRIQUE R.; VELAZQUEZ, ELIZABETH N.; MEJIA, RAUL M.; CUNEO, ALDO; PEREZ-STABLE, ELISEO J.

    2014-01-01

    Resumen El rastreo de cáncer colorrectal (CCR) cuenta con fuertes evidencias en su favor. Datos preliminares indican que a pesar de ello no se lleva a cabo con la frecuencia adecuada. Se intenta aquí determinar, dentro de un Sistema de Salud que cuenta con los recursos necesarios, los elementos que facilitan o generan barreras para concretar esta práctica preventiva, cuántos individuos lo ponen en práctica y qué predice esta conducta. Se realizó una encuesta telefónica a los afiliados de una Obra Social de empleados de la Universidad de Buenos Aires, de los que 132 completaron el cuestionario (tasa de respuesta 70%). Los elementos considerados facilitadores del rastreo obtuvieron respuestas afirmativas en el 64 a 97%, mientras que los que definían barreras un 11 a 27%. En este último grupo, una categoría diferenciada la constituía el miedo a los efectos adversos: 39%, y el sentimiento de vergüenza relacionado con los procedimientos: 30%. Un 33% de los encuestados tenían hecho un método de rastreo, mayoritariamente de sangre oculta (27), sigmoideoscopía (11) y colonoscopía (20). Una mayoría afirmó que “se haría el procedimiento si el médico se lo recomendara” (95%), o “no se lo haría excepto que su médico se lo aconseje” (87%). Contestar afirmativamente que “los médicos hacen lo mejor para los pacientes” se asoció con haberse hecho un método de rastreo de CCR, OR 1.55 (IC 95%: 1.02-2.37) p: 0.04. El grupo de individuos estudiado parece bien predispuesto para el rastreo del CCR, la recomendación médica sería aquí un determinante prominente para ponerlo en práctica. PMID:19414294

  19. Developmental endothelial locus-1 (Del-1) is a homeostatic factor in the central nervous system limiting neuroinflammation and demyelination

    PubMed Central

    Neuwirth, Ales; Economopoulou, Matina; Chatzigeorgiou, Antonios; Chung, Kyoung-Jin; Bittner, Stefan; Lee, Seung-Hwan; Langer, Harald; Samus, Maryna; Kim, Hyesoon; Cho, Geum-Sil; Ziemssen, Tjalf; Bdeir, Khalil; Chavakis, Emmanouil; Koh, Jae-Young; Boon, Louis; Hosur, Kavita; Bornstein, Stefan R.; Meuth, Sven G.; Hajishengallis, George; Chavakis, Triantafyllos

    2014-01-01

    Inflammation in the central nervous system (CNS) and disruption of its immune privilege are major contributors to the pathogenesis of multiple sclerosis (MS) and of its rodent counterpart, experimental autoimmune encephalomyelitis (EAE). We have previously identified developmental endothelial locus-1 (Del-1) as an endogenous anti-inflammatory factor, which inhibits integrin-dependent leukocyte adhesion. Here we show that Del-1 contributes to the immune privilege status of the CNS. Intriguingly, Del-1 expression decreased in chronic active MS lesions and in the inflamed CNS in the course of EAE. Del-1-deficiency was associated with increased EAE severity, accompanied by increased demyelination and axonal loss. As compared to control mice, Del-1−/− mice displayed enhanced disruption of the blood brain barrier and increased infiltration of neutrophil granulocytes in the spinal cord in the course of EAE, accompanied by elevated levels of inflammatory cytokines, including IL-17. The augmented levels of IL-17 in Del-1-deficiency derived predominantly from infiltrated CD8+ T cells. Increased EAE severity and neutrophil infiltration due to Del-1-deficiency was reversed in mice lacking both Del-1 and IL-17-receptor, indicating a crucial role for the IL-17/neutrophil inflammatory axis in EAE pathogenesis in Del-1−/− mice. Strikingly, systemic administration of Del-1-Fc ameliorated clinical relapse in relapsing-remitting EAE. Therefore, Del-1 is an endogenous homeostatic factor in the CNS protecting from neuroinflammation and demyelination. Our findings provide mechanistic underpinnings for the previous implication of Del-1 as a candidate MS susceptibility gene and suggest that Del-1-centered therapeutic approaches may be beneficial in neuroinflammatory and demyelinating disorders. PMID:25385367

  20. Unravelling druggable signalling networks that control F508del-CFTR proteostasis.

    PubMed

    Hegde, Ramanath Narayana; Parashuraman, Seetharaman; Iorio, Francesco; Ciciriello, Fabiana; Capuani, Fabrizio; Carissimo, Annamaria; Carrella, Diego; Belcastro, Vincenzo; Subramanian, Advait; Bounti, Laura; Persico, Maria; Carlile, Graeme; Galietta, Luis; Thomas, David Y; Di Bernardo, Diego; Luini, Alberto

    2015-01-01

    Cystic fibrosis (CF) is caused by mutations in CF transmembrane conductance regulator (CFTR). The most frequent mutation (F508del-CFTR) results in altered proteostasis, that is, in the misfolding and intracellular degradation of the protein. The F508del-CFTR proteostasis machinery and its homeostatic regulation are well studied, while the question whether 'classical' signalling pathways and phosphorylation cascades might control proteostasis remains barely explored. Here, we have unravelled signalling cascades acting selectively on the F508del-CFTR folding-trafficking defects by analysing the mechanisms of action of F508del-CFTR proteostasis regulator drugs through an approach based on transcriptional profiling followed by deconvolution of their gene signatures. Targeting multiple components of these signalling pathways resulted in potent and specific correction of F508del-CFTR proteostasis and in synergy with pharmacochaperones. These results provide new insights into the physiology of cellular proteostasis and a rational basis for developing effective pharmacological correctors of the F508del-CFTR defect. PMID:26701908

  1. Unravelling druggable signalling networks that control F508del-CFTR proteostasis

    PubMed Central

    Hegde, Ramanath Narayana; Parashuraman, Seetharaman; Capuani, Fabrizio; Carissimo, Annamaria; Carrella, Diego; Belcastro, Vincenzo; Subramanian, Advait; Bounti, Laura; Persico, Maria; Carlile, Graeme; Galietta, Luis; Thomas, David Y; Di Bernardo, Diego; Luini, Alberto

    2015-01-01

    Cystic fibrosis (CF) is caused by mutations in CF transmembrane conductance regulator (CFTR). The most frequent mutation (F508del-CFTR) results in altered proteostasis, that is, in the misfolding and intracellular degradation of the protein. The F508del-CFTR proteostasis machinery and its homeostatic regulation are well studied, while the question whether ‘classical’ signalling pathways and phosphorylation cascades might control proteostasis remains barely explored. Here, we have unravelled signalling cascades acting selectively on the F508del-CFTR folding-trafficking defects by analysing the mechanisms of action of F508del-CFTR proteostasis regulator drugs through an approach based on transcriptional profiling followed by deconvolution of their gene signatures. Targeting multiple components of these signalling pathways resulted in potent and specific correction of F508del-CFTR proteostasis and in synergy with pharmacochaperones. These results provide new insights into the physiology of cellular proteostasis and a rational basis for developing effective pharmacological correctors of the F508del-CFTR defect. DOI: http://dx.doi.org/10.7554/eLife.10365.001 PMID:26701908

  2. CHEK2 c.1100delC allele is rarely identified in Greek breast cancer cases.

    PubMed

    Apostolou, Paraskevi; Fostira, Florentia; Papamentzelopoulou, Myrto; Michelli, Maria; Panopoulos, Christos; Fountzilas, George; Konstantopoulou, Irene; Voutsinas, Gerassimos E; Yannoukakos, Drakoulis

    2015-04-01

    The CHEK2 gene encodes a protein kinase that plays a crucial role in maintenance of genomic integrity and the DNA repair mechanism. CHEK2 germline mutations are associated with increased risk of breast cancer and other malignancies. From a clinical perspective, the most significant mutation identified is the c.1100delC mutation, which is associated with an approximately 25% lifetime breast cancer risk. The distribution of this mutation shows wide geographical variation; it is more prevalent in the Northern European countries and less common, or even absent, in Southern Europe. In order to estimate the frequency of the CHEK2 c.1100delC mutation in Greek breast cancer patients, we genotyped 2,449 patients (2,408 females and 41 males), which was the largest series ever tested for c.1100delC. The mean age of female and male breast cancer diagnosis was 49 and 59 years, respectively. All patients had previously tested negative for the Greek BRCA1 founder and recurrent mutations. The CHEK2 c.1100delC mutation was detected in 0.16% (4 of 2,408) of females, all of whom were diagnosed with breast cancer before the age of 50 years. Only one c.1100delC carrier was reported with breast cancer family history. The present study indicates that the CHEK2 c.1100delC mutation does not contribute substantially to hereditary breast cancer in patients of Greek descent. PMID:25835597

  3. Breast tumors from CHEK2 1100delC-mutation carriers: genomic landscape and clinical implications

    PubMed Central

    2011-01-01

    Introduction Checkpoint kinase 2 (CHEK2) is a moderate penetrance breast cancer risk gene, whose truncating mutation 1100delC increases the risk about twofold. We investigated gene copy-number aberrations and gene-expression profiles that are typical for breast tumors of CHEK2 1100delC-mutation carriers. Methods In total, 126 breast tumor tissue specimens including 32 samples from patients carrying CHEK2 1100delC were studied in array-comparative genomic hybridization (aCGH) and gene-expression (GEX) experiments. After dimensionality reduction with CGHregions R package, CHEK2 1100delC-associated regions in the aCGH data were detected by the Wilcoxon rank-sum test. The linear model was fitted to GEX data with R package limma. Genes whose expression levels were associated with CHEK2 1100delC mutation were detected by the bayesian method. Results We discovered four lost and three gained CHEK2 1100delC-related loci. These include losses of 1p13.3-31.3, 8p21.1-2, 8p23.1-2, and 17p12-13.1 as well as gains of 12q13.11-3, 16p13.3, and 19p13.3. Twenty-eight genes located on these regions showed differential expression between CHEK2 1100delC and other tumors, nominating them as candidates for CHEK2 1100delC-associated tumor-progression drivers. These included CLCA1 on 1p22 as well as CALCOCO1, SBEM, and LRP1 on 12q13. Altogether, 188 genes were differentially expressed between CHEK2 1100delC and other tumors. Of these, 144 had elevated and 44, reduced expression levels. Our results suggest the WNT pathway as a driver of tumorigenesis in breast tumors of CHEK2 1100delC-mutation carriers and a role for the olfactory receptor protein family in cancer progression. Differences in the expression of the 188 CHEK2 1100delC-associated genes divided breast tumor samples from three independent datasets into two groups that differed in their relapse-free survival time. Conclusions We have shown that copy-number aberrations of certain genomic regions are associated with CHEK2 mutation

  4. ``Campo del Cielo'' Meteorites: Astronomical Heritage and Cultural Colonialism

    NASA Astrophysics Data System (ADS)

    López, Alejandro Martín; Altman, Agustina

    2012-09-01

    In the province of Chaco, Argentina, there is a very unique dispersion of metallic meteorites called ``Campo del Cielo''. One of the meteoric fragments of this dispersion, the meteorite called ``El Chaco'', consisting of 37 tons, is the second heaviest in the world. These meteorites are of great importance to the worldview of the Moqoit, aboriginal people that inhabit this region. For the local Creole population the meteorites are also relevant, that's why they have being cited in numerous documents and reports since the colonial period. During the first months of 2012, two Argentine artists and the Artistic Director of the German contemporary art exhibition called dOCUMENTA (13) tried to move ``El Chaco'' meteorite to Germany in order to exhibit it as an artistic object. Due to the fact that moving the meteorite could have a negative impact according to the Moqoit cosmology and that they were not able to participate in the decision they begun a manifestation against the movement of El Chaco. The opposition made by aboriginal communities and experts in cultural astronomy was able to stop the transfer. The whole process and its impact on the local community have promoted a deep discussion about art, science and cultural colonialism. In this paper we aim to address this debate and its consequences. This will allow us to think about contemporary forms of colonialism that are hidden in many scientific and artistic projects. Furthermore, we aim to debate about the most effective ways of protecting astronomical heritage in the Third World.

  5. MALARIA VECTORS IN SAN JOSÉDEL GUAVIARE, ORINOQUIA, COLOMBIA

    PubMed Central

    JIMÉNEZ, IRENE P.; CONN, JAN E.; BROCHERO, HELENA

    2015-01-01

    This study was conducted to determine Anopheles species composition and their natural infectivity by human Plasmodium in 2 localities with the highest malaria transmission in San Jose del Guaviare, Guaviare, Colombia. A total of 1,009 Anopheles mosquitoes were collected using human landing catches during 8 months in 2010. Anopheles darlingi was the most abundant (83.2%) followed by An. albitarsis s.l. (8.6%), Anopheles braziliensis (3.8%), An. oswaldoi s.l. (1%), and An. rangeli (0.3%). Anopheles darlingi showed the highest human biting rate, and it was found naturally infected with Plasmodium vivax VK210 (0.119%) using enzyme-linked immunosorbent assays. All species were collected biting both indoors and outdoors. Anopheles darlingi showed biting activity overnight with an indoor peak between 1200–0100 h. Therefore, we recommend that malaria prevention strategies focus on 1) insecticide-treated nets to reduce human–vector contact when people are most exposed and unprotected; 2) accurate diagnoses; 3) adequate treatment for patients; 4) more timely epidemiological notification; and 5) improved entomological surveillance. PMID:25102591

  6. Seismicity following the 1985 eruption of Nevado del Ruiz, Colombia

    USGS Publications Warehouse

    Zollweg, J.E.

    1990-01-01

    Over 200 of the best-recorded earthquakes occurring near Nevado del Ruiz, Colombia, between December 1985 and May 1986 are examined for spatial patterns, information on local stress orientations, and evidence for seismogenic structures that may be related to magma-transport processes. These earthquakes occurred following the devastating eruption of November 13, 1985. Earthquake activity that is probably related to the volcanic system occurs over a large area, of the order of 50 km2. A pattern of earthquakes beneath the southern half of Ruiz may be the expression of a conduit system, but evidence is inconclusive due to low spatial resolution of most hypocenters. Epicenter and first-motion plots suggest most earthquakes occur on small faults of varying orientation. Most seismicity during this time period was unrelated to mapped faults, including some with Holocene offsets, except for the Villamaria Fault near Ruiz's northeast sector. Composite focal mechanisms show a variation of nearly 90?? in the strike of T-axes and indicate Ruiz is in a zone of local extension. ?? 1990.

  7. Ethnoveterinary medicine in the Arribes del Duero, western Spain.

    PubMed

    González, José A; García-Barriuso, Mónica; Amich, Francisco

    2011-06-01

    Currently, traditional ethnoveterinary practices are rare in Europe and the plants used previously have been replaced by the modern drugs used by national veterinary services. However, in some rural areas of the Mediterranean basin these traditional practices persist. Here we analyze the plant resources still used, or that have been used up until recently, for the treatment of the health and comfort of animals in a region in the central-western part of the Iberian Peninsula, the Arribes del Duero. We document the use of 84 species, belonging to 39 families (with a total of 2243 use-reports), and 62 herbal remedies based on the use of a single plant species (43) and cited by at least three independent informants. The veterinary use of the Ranunculaceae Clematis campaniflora is reported for the first time. We also identify several plants used as bedding or fodder for livestock and discuss the relevance of some toxic plants and some "magical-curative" aspects reported in the territory. PMID:21461643

  8. Paso del Norte ozone study VOC measurements, 1996

    SciTech Connect

    Seila, R.L.; Main, H.; Arriaga, J.L.; Martinez, G.V.; Ramadan, A.B.

    1999-11-01

    The results of VOC determinations of ambient air samples collected at surface air quality monitoring sites and near sources of interest on the US and Mexican side of the border during six weeks of the 1996 Paso del Norte Ozone Study are reported. Carbonyl samples were collected on DNPH impregnated cartridges at three surface sites and analyzed by HPLC to quantify 13, C-1 to C-8 species. Whole air samples were collected in electro-polished stainless steel canisters which were returned to laboratory for determination of C-2 to C-10+ hydrocarbons by cryogenic preconcentration capillary gas chromatography with flame ionization detection (gc-fid). Several sources were sampled: rush hour traffic, propane-powered bus exhaust, automobile paint shop emissions, propane fuel, petroleum refinery, and industrial manufacturing site. Spatial and temporal characteristics of VOC species concentrations and compositions are presented. Overall surface TNMOC values ranged from 0.1 to 3.4 ppmC with the highest concentrations recorded in the morning at three vehicle-dominated sites, two in Cuidad Juarez and one in downtown El Paso. Toluene in El Paso samples and propane, which is used as a cooking and transportation fuel in Cuidad Juarez, were the most abundant hydrocarbons.

  9. Paso del Norte ozone study VOC measurements, 1996

    SciTech Connect

    Seila, R.L.; Main, H.; Arriaga, J.L.; Martinez, G.V.; Ramadan, A.B.

    1999-01-01

    The results of VOC determinations of ambient air samples collected at surface air quality monitoring sites and near sources of interest on the US and Mexican side of the border during six weeks of the 1996 Paso del Norte Ozone Study are reported. Carbonyl samples were collected on DNPH impregnated cartridges at three surface sites and analyzed by HPLC to quantify 13, C-1 to C-8 species. Whole air samples were collected in electro-polished stainless steel canisters which were returned to laboratory for determination of C-2 to C-10+ hydrocarbons by cryogenic preconcentration capillary gas chromatography with flame ionization detection (gc-fid). Several sources were sampled: rush hour traffic, propane-powered bus exhaust, automobile paint shop emissions, propane fuel, petroleum refinery, and industrial manufacturing site. Spatial and temporal characteristics of VOC species concentrations and compositions are presented. Overall surface TNMOC values ranged from 0.1 to 3.4 ppmC with the highest concentrations recorded in the morning at three vehicle-dominated sites, two in Cuidad Juarez and one in downtown El Paso. Toluene in El Paso samples and propane, which is used as a cooking and transportation fuel in Cuidad Juarez, were the most abundant hydrocarbons.

  10. El uso de la neuromodulación para el tratamiento del temblor

    PubMed Central

    Bendersky, Damián; Ajler, Pablo; Yampolsky, Claudio

    2014-01-01

    Introducción: El temblor puede ser un desorden incapacitante y el tratamiento de primera línea para estos pacientes es farmacológico. Sin embargo, este tratamiento puede llevar a una reducción satisfactoria del temblor en sólo el 50% de los pacientes con temblor esencial. La talamotomía era el tratamiento de elección para el temblor refractario al tratamiento médico hasta que comenzó a utilizarse la estimulación cerebral profunda (ECP) del núcleo ventral intermedio (Vim) del tálamo. En la actualidad, raramente se realiza la talamotomía. Métodos: Este artículo es una revisión no sistemática de las indicaciones, resultados, parámetros de programación y técnica quirúrgica de la ECP del Vim para el tratamiento del temblor. Resultados: Aunque los resultados clínicos son similares usando la talamotomía o la ECP del Vim, la primera causa más efectos adversos que la última. Además, la ECP puede ser usada bilateralmente, mientras que la talamotomía tiene un alto riesgo de causar disartria cuando se realiza de ambos lados. La ECP del Vim logró una adecuada mejoría del temblor en varias series de pacientes con temblor causado por temblor esencial, enfermedad de Parkinson o esclerosis múltiple. Además del Vim, hay otros blancos que están siendo usados por varios autores, tales como la zona incerta y las radiaciones prelemniscales. Conclusión: La ECP del Vim es un tratamiento útil para el temblor incapacitante refractario al tratamiento médico. Es esencial realizar una precisa selección de pacientes, así como utilizar una técnica quirúrgica correcta. Aún se desconoce el mejor blanco estereotáctico para el temblor, aunque el Vim es el más usado. PMID:25165613

  11. Screening for F508del as a first step in the molecular diagnosis of cystic fibrosis*,**

    PubMed Central

    Marson, Fernando Augusto de Lima; Bertuzzo, Carmen Silvia; Ribeiro, Maria Ângela Gonçalves de Oliveira; Ribeiro, Antônio Fernando; Ribeiro, José Dirceu

    2013-01-01

    OBJECTIVE: To determine the relevance of screening for the F508del mutation of the cystic fibrosis transmembrane conductance regulator gene as a first step in the genetic diagnosis of cystic fibrosis (CF) by associating the genotype with various clinical variables. METHODS: We evaluated 180 CF patients regarding the F508del mutation. The clinical data were obtained from the medical records of the patients and from interviews with their parents or legal guardians. RESULTS: Of the 180 patients studied, 65 (36.1%) did not carry the F508del mutation (group 0 [G0]), 67 (37.2%) were F508del heterozygous (G1), and 48 (26.7%) were F508del homozygous (G2). All three groups showed associations with the clinical variables. Homozygosis was associated with younger patients, younger age at CF diagnosis, and younger age at the first isolation of Pseudomonas aeruginosa (PA), as well as with higher prevalence of pancreatic insufficiency (PI) and non-mucoid PA (NMPA) colonization. In comparison with G1+G2 patients, G0 patients were older; first experienced clinical symptoms, digestive disease, and pulmonary disease at an older age; were older at CF diagnosis and at first PA isolation; and had a lower prevalence of PI and meconium ileus, as well as of colonization by NMPA, mucoid PA, and Burkholderia cepacia. In G1 patients, values were intermediate for age at CF diagnosis; age at first PA isolation, first pulmonary symptoms, and first clinical manifestations; MPA colonization; and OR for PI. CONCLUSIONS: The identification of F508del in 63.9% of the patients studied showed that this can be a useful tool as a first step in the genetic diagnosis of CF. The F508del genotype was associated with clinical severity of the disease, especially with the variables related to CF onset. PMID:23857699

  12. Manipulating proteostasis to repair the F508del-CFTR defect in cystic fibrosis.

    PubMed

    Esposito, Speranza; Tosco, Antonella; Villella, Valeria R; Raia, Valeria; Kroemer, Guido; Maiuri, Luigi

    2016-12-01

    Cystic fibrosis (CF) is a lethal monogenic disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene that entails the (diagnostic) increase in sweat electrolyte concentrations, progressive lung disease with chronic inflammation and recurrent bacterial infections, pancreatic insufficiency, and male infertility. Therapies aimed at restoring the CFTR defect have emerged. Thus, a small molecule which facilitates chloride channel opening, the potentiator Ivacaftor, has been approved for the treatment of CF patients bearing a particular class of rare CFTR mutations. However, small molecules that directly target the most common misfolded CFTR mutant, F508del, and improve its intracellular trafficking in vitro, have been less effective than expected when tested in CF patients, even in combination with Ivacaftor. Thus, new strategies are required to circumvent the F508del-CFTR defect. Airway and intestinal epithelial cells from CF patients bearing the F508del-CFTR mutation exhibit an impressive derangement of cellular proteostasis, with oxidative stress, overactivation of the tissue transglutaminase (TG2), and disabled autophagy. Proteostasis regulators such as cysteamine can rescue and stabilize a functional F508del-CFTR protein through suppressing TG2 activation and restoring autophagy in vivo in F508del-CFTR homozygous mice, in vitro in CF patient-derived cell lines, ex vivo in freshly collected primary patient's nasal cells, as well as in a pilot clinical trial involving homozygous F508del-CFTR patients. Here, we discuss how the therapeutic normalization of defective proteostasis can be harnessed for the treatment of CF patients with the F508del-CFTR mutation. PMID:26976279

  13. Modelo semi-empírico de protuberancia solar a partir del diagnóstico de densidades

    NASA Astrophysics Data System (ADS)

    Cirigliano, D.; Vial, J. C.; Rovira, M.

    A partir de la observación del espectro del quintuplete de C III alrededor de 1175 Å, se ha realizado el diagnóstico de la densidad y presión electrónica, basado en el cálculo del cociente de las intensidades observadas. Una vez establecida la densidad electrónica, y con el cálculo de las velocidades Doppler, hemos investigado el flujo de masa en la protuberancia en función de la temperatura. Estableciendo como hipótesis la conservación del número de partículas que ingresan y salen del cuerpo de la protuberancia, se investiga la variación del área de un tubo de flujo semi-empírico en función de la temperatura. A partir de dicho diagnóstico, se examina el comportamiento del radio del tubo magnético en función de la temperatura, los que dan cuenta de la abertura de las líneas de campo magnético que confinan el plasma y de la divergencia del campo magnético en diferentes alturas de la atmósfera solar.

  14. Resistivity structure of the Del Mar methane seep.

    NASA Astrophysics Data System (ADS)

    Kannberg, P. K.; Constable, S.

    2015-12-01

    In March of 2015 we mapped the resistivity structure of the Del Mar methane seep in the inner California borderlands using a deep towed electromagnetic (EM) source and receiver array. Located in the San Diego trough at a depth of 1km, the seep site is on the flank of a mound associated with a transpressive step in the San Diego trough fault. The seep site has previously been associated with seafloor pockmarks, acoustic wipeouts, chemosynthetic communities, and active methane bubble venting. Controlled source electromagnetic (CSEM) surveys are performed by deep-towing an EM source that is transmitting a known signal; this signal is detected by towed receivers. This transmitted signal is altered by the electrical properties of the surrounding environment. Compared to seismic methods, EM methods are largely insensitive to free gas, making it an especially useful tool for detecting electrically resistive methane hydrate in areas of active gas venting. We used a 50m dipole transmitting 100A, with 3-axis electric field receivers spaced at 130m, 230m, 330m, and 430m behind the transmitter dipole center. The receiver data are inverted using MARE2DEM, a finite element 2D inversion routine. The inversion results show the background resistivity of the trough sediments to be about 1-2 ohmm, and are largely featureless outside of the seep site. However at the seep site we see a decanter-shaped 100 ohmm resistor whose base is 100m below the seafloor, and 1km wide at its widest. This feature narrows at the top to form a pipe structure about 200m wide that extends to the seafloor. These resistive structures are interpreted to be methane hydrate resulting from methane rich fluid flow along faults associated with the transpressional system that brackets the seep site.

  15. Predicting Nonspecific Ion Binding Using DelPhi

    PubMed Central

    Petukh, Marharyta; Zhenirovskyy, Maxim; Li, Chuan; Li, Lin; Wang, Lin; Alexov, Emil

    2012-01-01

    Ions are an important component of the cell and affect the corresponding biological macromolecules either via direct binding or as a screening ion cloud. Although some ion binding is highly specific and frequently associated with the function of the macromolecule, other ions bind to the protein surface nonspecifically, presumably because the electrostatic attraction is strong enough to immobilize them. Here, we test such a scenario and demonstrate that experimentally identified surface-bound ions are located at a potential that facilitates binding, which indicates that the major driving force is the electrostatics. Without taking into consideration geometrical factors and structural fluctuations, we show that ions tend to be bound onto the protein surface at positions with strong potential but with polarity opposite to that of the ion. This observation is used to develop a method that uses a DelPhi-calculated potential map in conjunction with an in-house-developed clustering algorithm to predict nonspecific ion-binding sites. Although this approach distinguishes only the polarity of the ions, and not their chemical nature, it can predict nonspecific binding of positively or negatively charged ions with acceptable accuracy. One can use the predictions in the Poisson-Boltzmann approach by placing explicit ions in the predicted positions, which in turn will reduce the magnitude of the local potential and extend the limits of the Poisson-Boltzmann equation. In addition, one can use this approach to place the desired number of ions before conducting molecular-dynamics simulations to neutralize the net charge of the protein, because it was shown to perform better than standard screened Coulomb canned routines, or to predict ion-binding sites in proteins. This latter is especially true for proteins that are involved in ion transport, because such ions are loosely bound and very difficult to detect experimentally. PMID:22735539

  16. 1996 Paso del Norte ozone study VOC measurements

    SciTech Connect

    Seila, R.L.; Main, H.; Arriaga, J.L.; Martinez, G.; Ramadan, A.B.

    1999-07-01

    Ambient air VOC samples were collected at surface air quality monitoring sites, near sources of interest, and aloft on the US and Mexican side of the border during a six week period of the 1996 Paso del Norte Ozone Study. On nine intensive operations (IOP) days, when high ozone concentrations were forecast, five 2-hr samples were collected at five IOP sites, three on the US side and two on the Mexican side. Six special survey sites on the US side and two on the Mexican side were sampled to characterize up-wind, down-wind and other emissions. In Ciudad Juarez, rush hour traffic, propane-powered bus exhaust, automobile paint shop emissions, propane and butane fuels, and an industrial manufacturing site were sampled. Carbonyl samples were collected at three surface sites. Carbonyl and canister grab samples were also collected during aircraft and hot air balloon flights. Most of the hydrocarbon samples were collected in electro-polished stainless steel canisters which were returned to laboratories for determination of C-2 to C-10+ hydrocarbons by cryogenic preconcentration GC-FID. The carbonyl samples were collected on DNPH impregnated C-18 Sep-Pak cartridges and analyzed by HPLC to quantify 13, C-1 to C-8 species. This paper presents the spatial and temporal characteristics of VOC species concentrations and compositions to examine the differences and similarities of the various locations and time periods. Overall surface TNMOC values ranged from 0.1 to 3.4 ppmC with the highest concentrations being recorded in the morning at three vehicle-dominated sites, two in Ciudad Juarez and one in downtown El Paso. Toluene in El Paso samples and propane, which is used as a cooking and transportation fuel in Ciudad Juarez, were the most abundant hydrocarbons. The most abundant carbonyls were acetaldehyde and acetone.

  17. La implantacion del enfoque constructivista en el aula de ciencia: Estudio de caso multiple

    NASA Astrophysics Data System (ADS)

    Arroyo Betancourt, Luz I.

    Esta investigacion estudia la implantacion del enfoque constructivista en tres aulas de ciencia del contexto puertorriqueno. Se auscultaron las practicas educativas que utilizan maestras consideradas constructivistas y la correspondencia de sus practicas educativas con los elementos esenciales de la didactica que proponen los teoricos de los planteamientos constructivistas. Se ausculto, ademas, a que vision del enfoque constructivista responden las expresiones de las maestras acerca de su practica educativa y como compara con su quehacer, a la luz de los elementos esenciales de las visiones constructivistas piagetiana, social y radical. Se utilizo el diseno de estudio descriptivo de caso multiple. El estudio se baso en entrevistas a profundidad, revision de documentos y observacion no participativa a la sala de clases. El contexto fueron tres escuelas publicas de la Region Educativa de San Juan, una elemental, una intermedia y una superior. Los resultados confirmaron que la transicion hacia el enfoque constructivista es un proceso que toma tiempo, dedicacion y la participacion en adiestramientos y readiestramientos acerca del nuevo enfoque. Las maestras coinciden en la mayoria de las practicas educativas que utilizan para implantar el enfoque constructivista de ensenanza y difieren en algunas debido, probablemente, a que han tenido que adaptarlas a los correspondientes niveles de ensenanza: elemental, intermedio y superior. Dos de las maestras planifican por conceptos generadores, mientras que una de ellas planifica siguiendo la guia que recibe del Departamento de Educacion. Difieren ademas, en el enfasis que confieren al inquirir cientifico. Con relacion a la correspondencia entre la vision manifestada por las maestras a la luz de las visiones piagetiana, social y radical, aparentemente, las preguntas del protocolo de entrevistas no lograron evocar la informacion con suficiente profundidad, por lo que la investigadora tuvo que inferir las visiones de las

  18. Using Del-1 to Tip the Angiogenic Balance in Endothelial Cells in Modular Constructs

    PubMed Central

    Ciucurel, Ema C.; Vlahos, Alexander E.

    2014-01-01

    Modular tissue engineering is a method of building vascularized tissue-engineered constructs. Submillimeter-sized collagen pieces (modules) coated with a layer of endothelial cells (EC; vascular component), and with embedded functional cells, are self-assembled into a larger, three-dimensional tissue. In this study, we examined the use of developmental endothelial locus-1 (Del-1), an extracellular matrix protein with proangiogenic properties, as a means of tipping the angiogenic balance in human umbilical vein endothelial cells incorporated in modular tissue-engineered constructs. The motivation was to enhance the vascularization of these constructs upon transplantation in vivo, in this case, without the use of exogenous mesenchymal stromal cells. EC were transduced using a lentiviral construct to overexpress Del-1. The Del-1 EC formed more sprouts in a fibrin gel sprouting assay in vitro compared with eGFP (control) transduced EC, as expected. Del-1 EC had a distinct profile of gene expression (upregulation of matrix metalloproteinase-9 [MMP-9], urokinase-type plasminogen activator [uPA/PLAU], vascular endothelial growth factor [VEGF-A], and intercellular adhesion molecule-1 [ICAM-1]; downregulation of angiopoietin-2 [Ang2]), also supporting the notion of “tipping the angiogenic balance”. On the other hand, contrary to our expectations, when Del-1 EC-coated modules were implanted subcutaneously in a severe combined immunodeficient/beige animal model, the proangiogenic effect of Del-1 was less remarkable. There was only a small increase in the number of blood vessels formed in Del-1 implants compared with the eGFP implants, and only few blood vessels formed at the implant site in both cases. This was presumed due to limited EC survival after transplantation. We speculate that if we could improve EC survival in our study (for example, by adding other prosurvival factors or supporting cells), we would see a greater Del-1-induced angiogenic benefit in vivo as a

  19. Detecting a hierarchical genetic population structure via Multi-InDel markers on the X chromosome

    PubMed Central

    Fan, Guang Yao; Ye, Yi; Hou, Yi Ping

    2016-01-01

    Detecting population structure and estimating individual biogeographical ancestry are very important in population genetics studies, biomedical research and forensics. Single-nucleotide polymorphism (SNP) has long been considered to be a primary ancestry-informative marker (AIM), but it is constrained by complex and time-consuming genotyping protocols. Following up on our previous study, we propose that a multi-insertion-deletion polymorphism (Multi-InDel) with multiple haplotypes can be useful in ancestry inference and hierarchical genetic population structures. A validation study for the X chromosome Multi-InDel marker (X-Multi-InDel) as a novel AIM was conducted. Genetic polymorphisms and genetic distances among three Chinese populations and 14 worldwide populations obtained from the 1000 Genomes database were analyzed. A Bayesian clustering method (STRUCTURE) was used to discern the continental origins of Europe, East Asia, and Africa. A minimal panel of ten X-Multi-InDels was verified to be sufficient to distinguish human ancestries from three major continental regions with nearly the same efficiency of the earlier panel with 21 insertion-deletion AIMs. Along with the development of more X-Multi-InDels, an approach using this novel marker has the potential for broad applicability as a cost-effective tool toward more accurate determinations of individual biogeographical ancestry and population stratification. PMID:27535707

  20. The RGD finger of Del-1 is a unique structural feature critical for integrin binding

    SciTech Connect

    Schürpf, Thomas; Chen, Qiang; Liu, Jin-huan; Wang, Rui; Springer, Timothy A.; Wang, Jia-huai

    2012-11-13

    Developmental endothelial cell locus-1 (Del-1) glycoprotein is secreted by endothelial cells and a subset of macrophages. Del-1 plays a regulatory role in vascular remodeling and functions in innate immunity through interaction with integrin {alpha}{sub V}{beta}{sub 3}. Del-1 contains 3 epidermal growth factor (EGF)-like repeats and 2 discoidin-like domains. An Arg-Gly-Asp (RGD) motif in the second EGF domain (EGF2) mediates adhesion by endothelial cells and phagocytes. We report the crystal structure of its 3 EGF domains. The RGD motif of EGF2 forms a type II' {beta} turn at the tip of a long protruding loop, dubbed the RGD finger. Whereas EGF2 and EGF3 constitute a rigid rod via an interdomain calcium ion binding site, the long linker between EGF1 and EGF2 lends considerable flexibility to EGF1. Two unique O-linked glycans and 1 N-linked glycan locate to the opposite side of EGF2 from the RGD motif. These structural features favor integrin binding of the RGD finger. Mutagenesis data confirm the importance of having the RGD motif at the tip of the RGD finger. A database search for EGF domain sequences shows that this RGD finger is likely an evolutionary insertion and unique to the EGF domain of Del-1 and its homologue milk fat globule-EGF 8. The RGD finger of Del-1 is a unique structural feature critical for integrin binding.

  1. Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis

    PubMed Central

    Wang, Zhen; Tran, Misha C.; Bhatia, Namrata J.; Hsing, Alexander W.; Chen, Carol; LaRussa, Marie F.; Fattakhov, Ernst; Rashidi, Vania; Jang, Kyu Yun; Choo, Kevin J.; Nie, Xingju; Mathy, Jonathan A.; Longaker, Michael T.; Dauskardt, Reinhold H.; Helms, Jill A.; Yang, George P.

    2016-01-01

    Objective We identified significant expression of the matricellular protein, DEL1, in hypertrophic and mature cartilage during development. We hypothesized that this tissue-specific expression indicated a biological role for DEL1 in cartilage biology. Methods Del1 KO and WT mice had cartilage thickness evaluated by histomorphometry. Additional mice underwent medial meniscectomy to induce osteoarthritis, and were assayed at 1 week for apoptosis by TUNEL staining and at 8 weeks for histology and OA scoring. In vitro proliferation and apoptosis assays were performed on primary chondrocytes. Results Deletion of the Del1 gene led to decreased amounts of cartilage in the ears and knee joints in mice with otherwise normal skeletal morphology. Destabilization of the knee led to more severe OA compared to controls. In vitro, DEL1 blocked apoptosis in chondrocytes. Conclusion Osteoarthritis is among the most prevalent diseases worldwide and increasing in incidence as our population ages. Initiation begins with an injury resulting in the release of inflammatory mediators. Excessive production of inflammatory mediators results in apoptosis of chondrocytes. Because of the limited ability of chondrocytes to regenerate, articular cartilage deteriorates leading to the clinical symptoms including severe pain and decreased mobility. No treatments effectively block the progression of OA. We propose that direct modulation of chondrocyte apoptosis is a key variable in the etiology of OA, and therapies aimed at preventing this important step represent a new class of regenerative medicine targets. PMID:27505251

  2. Detecting a hierarchical genetic population structure via Multi-InDel markers on the X chromosome.

    PubMed

    Fan, Guang Yao; Ye, Yi; Hou, Yi Ping

    2016-01-01

    Detecting population structure and estimating individual biogeographical ancestry are very important in population genetics studies, biomedical research and forensics. Single-nucleotide polymorphism (SNP) has long been considered to be a primary ancestry-informative marker (AIM), but it is constrained by complex and time-consuming genotyping protocols. Following up on our previous study, we propose that a multi-insertion-deletion polymorphism (Multi-InDel) with multiple haplotypes can be useful in ancestry inference and hierarchical genetic population structures. A validation study for the X chromosome Multi-InDel marker (X-Multi-InDel) as a novel AIM was conducted. Genetic polymorphisms and genetic distances among three Chinese populations and 14 worldwide populations obtained from the 1000 Genomes database were analyzed. A Bayesian clustering method (STRUCTURE) was used to discern the continental origins of Europe, East Asia, and Africa. A minimal panel of ten X-Multi-InDels was verified to be sufficient to distinguish human ancestries from three major continental regions with nearly the same efficiency of the earlier panel with 21 insertion-deletion AIMs. Along with the development of more X-Multi-InDels, an approach using this novel marker has the potential for broad applicability as a cost-effective tool toward more accurate determinations of individual biogeographical ancestry and population stratification. PMID:27535707

  3. Pseudomonas aeruginosa Reduces VX-809 Stimulated F508del-CFTR Chloride Secretion by Airway Epithelial Cells

    PubMed Central

    Stanton, Bruce A.; Coutermarsh, Bonita; Barnaby, Roxanna; Hogan, Deborah

    2015-01-01

    Background P. aeruginosa is an opportunistic pathogen that chronically infects the lungs of 85% of adult patients with Cystic Fibrosis (CF). Previously, we demonstrated that P. aeruginosa reduced wt-CFTR Cl secretion by airway epithelial cells. Recently, a new investigational drug VX-809 has been shown to increase F508del-CFTR Cl secretion in human bronchial epithelial (HBE) cells, and, in combination with VX-770, to increase FEV1 (forced expiratory volume in 1 second) by an average of 3-5% in CF patients homozygous for the F508del-CFTR mutation. We propose that P. aeruginosa infection of CF lungs reduces VX-809 + VX-770- stimulated F508del-CFTR Cl secretion, and thereby reduces the clinical efficacy of VX-809 + VX-770. Methods and Results F508del-CFBE cells and primary cultures of CF-HBE cells (F508del/F508del) were exposed to VX-809 alone or a combination of VX-809 + VX-770 for 48 hours and the effect of P. aeruginosa on F508del-CFTR Cl secretion was measured in Ussing chambers. The effect of VX-809 on F508del-CFTR abundance was measured by cell surface biotinylation and western blot analysis. PAO1, PA14, PAK and 6 clinical isolates of P. aeruginosa (3 mucoid and 3 non-mucoid) significantly reduced drug stimulated F508del-CFTR Cl secretion, and plasma membrane F508del-CFTR. Conclusion The observation that P. aeruginosa reduces VX-809 and VX-809 + VX-770 stimulated F508del CFTR Cl secretion may explain, in part, why VX-809 + VX-770 has modest efficacy in clinical trials. PMID:26018799

  4. High mountain soils and periglacial features at the Torres del Paine, National Park Torres del Paine, Chile.

    NASA Astrophysics Data System (ADS)

    Senra, Eduardo; Schaefer, Carlos; Simas, Felipe; Gjorup, Davi

    2015-04-01

    The Torres del Paine National Park (TPNP) is located on the southern limit of the Andean Southern Ice Field, part of the Magallanes and Antartica Chilena region, in the province of Ultima Esperanza. The TPNP has a very heterogeneous climate due to orographic influence and wet air masses from the Pacific. The geology is basically Cretaceous metasedimentary rocks and Miocene granitic plutons and batholiths. We studied the main soils and geoenvironments of Mt Ferrier mountain and its surroundings, based on soils , landforms and vegetation aspects. The geoenvironmental stratification was based on the combined variation and integration of pedo-litho-geomorphological features with the vegetation. WE used detailed geological maps, a DEM and slope maps and WorlView II satellite images. Fifteen soils profiles were sampled and classified according to Soil Taxonomy (2010) at all genovironments, ranging from 50 m a.s.l to the at high plateau just below the permanent snowline, under periglacial conditions (~1004m asl). Three soil temperature and moisture monitoring sites were set, allowing for 24 consecutive months (2011 to 2013). Seven geoenvironments were identified with distinct soil and landform characteristics, all with a similar geological substrate. The landform and vegetation have a strong connection with the landscape dynamic, controlling erosional and depositional processes, resulting from glacier advances and retreats in the Late Quaternary. Wind blown materials is widespread, in the form of loess material, accumulating in the higher parts of the landscape. On the other hand, accumulation of organic matter in the water-saturated depressions is common in all altitudes. Generally the soils are acidic and dystrophic, with little exceptions. The following geoenvironments were identified: Periglacial Tundra, Loess slopes, Talus and scarpmentd, Fluvio-glacial terraces, Fluvio-lacustrine plains, Moraines and Paleodunes. The regional pedology show the occurrence of five soil

  5. The novel complex allele [A238V;F508del] of the CFTR gene: clinical phenotype and possible implications for cystic fibrosis etiological therapies.

    PubMed

    Diana, Anna; Polizzi, Angela Maria; Santostasi, Teresa; Ratclif, Luigi; Pantaleo, Maria Giuseppina; Leonetti, Giuseppina; Iusco, Danila Rosa; Gallo, Crescenzio; Conese, Massimo; Manca, Antonio

    2016-06-01

    Few mutations in cis have been annotated for F508del homozygous patients. Southern Italy patients who at a first analysis appeared homozygous for the F508del mutation (n=63) or compound heterozygous for the F508del and another mutation in the cystic fibrosis transmembrane conductance regulator gene (n=155) were searched for the A238V mutation in exon 6. The allelic frequency of the complex allele [A238V;F508del] was 0.04. When the whole data set was used (comprised also of 56 F508del/F508del and 34 F508del/other mutation controls), no differences reached the statistical significance in the clinical parameters, except chloride concentrations which were lower in [A238V;F508del]/other mutation compared with F508del/other mutation (P=0.03). The two study groups presented less complications than the control groups. Within the minimal data set (34 F508del/F508del, 27 F508del/other mutation, 4 [A238V;F508del]/F508del cases and 5 [A238V;F508del]/other mutation cases); that is, presenting all the variables in each patient, forced expiratory volume in 1 s and forced vital capacity presented a trend to lower levels in the study groups in comparison with the F508del/F508del group, and C-reactive protein approximated statistically significant higher levels in the [A238V;F508del]/other mutation as compared with F508del/F508del patients (P=0.09). The analysis of statistical dependence among the variables showed a significant anticorrelation between chloride and body mass index in the [A238V;F508del]/other mutation group. In conclusion, the complex allele [A238V;F508del] seems to be associated with less general complications than in the control groups, on the other hand possibly giving a worse pulmonary phenotype and higher systemic/local inflammatory response. These findings have implications for the correct recruitment and clinical response of F508del patients in the clinical trials testing the new etiological drugs for cystic fibrosis. PMID:26911355

  6. Integrated global background monitoring network. Preliminary results from Torres del Paine and Olympic National Parks

    SciTech Connect

    Wiersma, G.B.; Kohler, A.; Boelcke, C.; Baker, G.; Harmon, M.; Weber, C.; Gonzales, J.

    1985-10-01

    During 1984, a pilot project was initiated for monitoring pollution at Torres del Paine National Park in southern Chile and Olympic National Park in the United States. These are two of three initial sites that are to be established as part of an integrated global backgound monitoring network. Eventually, the plan is to establish a world-wide system of such sites. We collected and analyzed samples of the soil, water, air, and two species of plants (moss and lichen). We also collected and analyzed samples of the forest litter. We compared the samples of soil and vegetation against reference samples. We also compared samples of soil, vegetation, and of organic material from Torres del Paine against similar samples from Olympic and Sequoia-Kings Canyon National Parks in the United States. Although the data is preliminary, it is in agreement with out initial hypothesis that Torres del Paine and Olympic National Parks are not a polluted sites.

  7. Biotic association and palaeoenvironmental reconstruction of the "Loma del Pterodaustro" fossil site (Early Cretaceous, Argentina)

    USGS Publications Warehouse

    Chiappe, L.; Rivarola, D.; Cione, A.; Fregenal-Martinez, M.; Sozzi, H.; Buatois, L.; Gallego, O.; Laza, J.; Romero, E.; Lopez-Arbarello, A.; Buscalioni, A.; Marsicano, C.; Adamonis, S.; Ortega, F.; McGehee, S.; Di, Iorio O.

    1998-01-01

    A sedimentological analysis of the basal section of the Early Cretaceous, lacustrine Lagarcito Formation at "Loma del Pterodaustro" (San Luis, Argentina) and a summary of its biological components are presented. Three sedimentological facies can be recognized in the basal sequence of the Lagarcito Formation. Fossil remains are particularly abundant in laminated claystones of a facies interpreted as deposits formed in offshore areas of the lake. The preservation of delicate structures allows recognition of these deposits as a Konservat Lagersta??tte. Up to now, rocks at "Loma del Pterodaustro" have yielded plants, conchostracans, semionotid and pleuropholid fishes, pterodactyloid pterosaurs, and a variety of invertebrate traces. The chronology of the Lagarcito Formation is discussed and it is concluded that this unit is of Albian age. The palaeoenvironment of deposition of the basal sequence of the Lagarcito Formation at "Loma del Pterodaustro" is interpreted as a perennial, shallow lake developed within an alluvial plain, under semiarid climatic conditions.

  8. del-type metrics in Einstein-Aether theory II: nonflat background in arbitrary dimensions

    NASA Astrophysics Data System (ADS)

    Gürses, Metin; Şentürk, Çetin

    2016-05-01

    It was previously proved that the Gödel-type metrics with flat three-dimensional background metric solve exactly the field equations of the Einstein-Aether theory in four dimensions. We generalize this result by showing that the stationary Gödel-type metrics with nonflat background in D dimensions solve exactly the field equations of the Einstein-Aether theory. The reduced field equations are the (D-1)-dimensional Euclidean Ricci-flat and the (D-1)-dimensional source-free Maxwell equations, and the parameters of the theory are left free except c1-c3=1. We give a method to produce exact solutions of the Einstein-Aether theory from the Gödel-type metrics in D dimensions. By using this method, we present explicit exact solutions to the theory by considering the particular cases: (D-1)-dimensional Euclidean flat, conformally flat, and Tangherlini backgrounds.

  9. La relatività debole. La fisica dello spazio e del tempo senza paradossi

    NASA Astrophysics Data System (ADS)

    Selleri, Franco

    2011-06-01

    Secondo Einstein e Poincaré la simultaneità di eventi che hanno luogo in punti diversi dello spazio può essere definita solo per convenzione. Dal punto di vista matematico si dimostra, quindi, che due diverse definizioni di simultaneità corrispondono a due diversi valori del coefficiente e1 della variabile spaziale x presente nelle trasformazioni di Lorentz. A partire da premesse normalmente accettate otterremo diverse dimostrazioni della necessità di reintrodurre il concetto di simultaneità assoluta. Le conseguenze cosmologiche della nuova struttura dello spazio e del tempo andranno contro la cosmologia del Big Bang. Inoltre, dopo questi risultati, il relativismo sopravviverà in una forma meno aspra ("relatività debole") perché risulter privo di quel campionario di paradossi portato dalla teoria della Relatività Speciale.

  10. Mejoras en el apuntado del telescopio de 2,15 mts de CASLEO

    NASA Astrophysics Data System (ADS)

    Aballay, J. L.; Casagrande, A. R.; Pereyra, P. F.; Marún, A. H.

    Con el objeto de optimizar el funcionamiento del telescopio de 2,15 mts. de CASLEO, se están eliminando los motores de calar, de guía y mecánica asociada. Para ésto, se están diseñando dos electrónicas que gobernarán, solamente, el motor de slew y el de tracking. Con el control del motor de slew se realizarán las funciones de slew y calar, controlando desde una PC la placa que maneja las rampas de velocidad. De este modo, el movimiento será programado y por lo tanto, más suave y preciso. Con el control del motor de tracking, a través de un generador de frecuencias programable desde una PC, se proveerá los movimientos necesarios para el tracking y guía.

  11. Deep source model for Nevado del Ruiz Volcano, Colombia, constrained by interferometric synthetic aperture radar observations

    NASA Astrophysics Data System (ADS)

    Lundgren, Paul; Samsonov, Sergey V.; López Velez, Cristian Mauricio; Ordoñez, Milton

    2015-06-01

    Nevado del Ruiz is part of a large volcano complex in the northern Andes of Colombia. Interferometric synthetic aperture radar observations from the RADARSAT-2 satellite since 2011 show steady inflation of the volcano since 2012 at 3-4 cm/yr. The broad (>20 km) deformation pattern from both ascending and descending track data constrain source models for either point or spheroidal sources, both located at >14 km beneath the surface (mean elevation 4.2 km) and 10 km SW of Nevado del Ruiz, below nearby Santa Isabel Volcano. Stress change computations for both sources in the context of a compressive regional stress indicate that dikes propagating from the source should become trapped in sills, possibly leading to a more complex pathway to the surface and explaining the significant lateral separation of the source and Nevado del Ruiz Volcano.

  12. L'eliosismologia: onde sismiche per studiare l'interno del Sole

    NASA Astrophysics Data System (ADS)

    Di Mauro, M. P.

    2014-12-01

    Negli ultimi cinquanta anni siamo stati testimoni di una straordinaria rivoluzione della conoscenza e comprensione della nostra stella grazie alla nascita dell'Eliosismologia, lo studio delle oscillazioni solari. Analogamente a ciò che accade nella Terra durante i terremoti, anche l'interno del Sole è pervaso continuamente da onde sismiche che provocano piccole oscillazioni, ovvero deformazioni della fotosfera. Le oscillazioni sono la manifestazione di diversi processi che avvengono all'interno della struttura del Sole e le frequenze sismiche dei modi osservati e misurati sulla superficie sono legate direttamente ai parametri fisici degli strati interni attraversati dalle onde sismiche. Lo studio delle oscillazioni rappresenta, quindi, l'unico metodo diretto per studiare la struttura e la dinamica interna del Sole. In questo articolo verranno illustrate le caratteristiche generali delle oscillazioni solari e verranno presentati i risultati importanti e i progressi notevoli raggiunti grazie all'Eliosismologia.

  13. CASE REPORT: Phenotypic presentation of the Ser63Del MPZ mutation

    PubMed Central

    Miller, Lindsey J.; Patzko, Agnes; Lewis, Richard A.; Shy, Michael E.

    2013-01-01

    Mutations in MPZ cause CMT1B, the second most frequent cause of CMT1. Elegant studies with Ser63del mice suggest that Ser63del MPZ is retained in the ER where it activates the unfolded protein response (UPR) that contributes to the neuropathy. Clinical information about patients with this mutation is limited. We present clinical and electrophysiological data on a large multigenerational family with CMT1B caused by Ser63del MPZ. The patients have a classical CMT1 phenotype that is much less severe than that of patients with Arg98Cys MPZ that also activates the UPR. These results suggest that clinical presentation along cannot predict which MPZ mutations will be retained in the ER and activate the UPR. PMID:22734905

  14. The 1985 Nevado del Ruiz volcano catastrophe: anatomy and retrospection

    NASA Astrophysics Data System (ADS)

    Voight, Barry

    1990-07-01

    This paper seeks to analyze in an objective way the circumstances and events that contributed to the 1985 Nevado del Ruiz catastrophe, in order to provide useful guidelines for future emergencies. The paper is organized into two principal parts. In the first part, an Anatomy of the catastrophe is developed as a step-by-step chronicle of events and actions taken by individuals and organizations during the period November 1984 through November 1985. This chronicle provides the essential background for the crucial events of November 13. This year-long period is broken down further to emphasize essential chapters: the gradual awareness of the awakening of the volcano; a long period of institutional skepticism reflecting an absence of credibility; the closure of the credibility gap with the September 11 phreatic eruption, followed by an intensive effort to gird for the worst; and a detailed account of the day of reckoning. The second part of the paper, Retrospection, examines the numerous complicated factors that influenced the catastrophic outcome, and attempts to cull a few "lessons from Armero" in order to avoid similar occurrences in the future. In a nutshell, the government on the whole acted responsibly but was not willing to bear the economic or political costs of early evacuation or a false alarm. Science accurately foresaw the hazards but was insufficiently precise to render reliable warning of the crucial event at the last possible minute. Catastrophe was therefore a calculated risk, and this combination — the limitations of predication/detection, the refusal to bear a false alarm and the lack of will to act on the uncertain information available — provided its immediate and most obvious causes. But because the crucial event occurred just two days before the Armero emergency-management plan was to be critically examined and improved, the numerous circumstances which delayed progress of emergency management over the previous year also may be said to have

  15. The 1985 Nevado del Ruiz volcano catastrophe: anatomy and retrospection

    NASA Astrophysics Data System (ADS)

    Voight, Barry

    1990-12-01

    This paper seeks to analyze in an objective way the circumstances and events that contributed to the 1985 Nevado del Ruiz catastrophe, in order to provide useful guidelines for future emergencies. The paper is organized into two principal parts. In the first part, an Anatomy of the catastrophe is developed as a step-by-step chronicle of events and actions taken by individuals and organizations during the period November 1984 through November 1985. This chronicle provides the essential background for the crucial events of November 13. This year-long period is broken down further to emphasize important chapters: the gradual awareness of the awakening of the volcano; a long period of institutional skepticism reflecting an absence of credibility; the closure of the credibility gap with the September 11 phreatic eruption, followed by an intensive effort to gird for the worst; and a detailed account of the day of reckoning. The second part of the paper, Retrospection, examines the numerous complicated factors that influenced the catastrophic outcome, and attempts to cull a few "lessons from Armero" in order to avoid similar occurrences in the future. In a nutshell, the government on the whole acted responsibly but was not willing to bear the economic or political costs of early evacuation or a false alarm. Science accurately foresaw the hazards but was insufficiently precise to render reliable warning of the crucial event at the last possible minute. Catastrophe was therefore a calculated risk, and this combination - the limitations of prediction/detection, the refusal to bear a false alarm and the lack of will to act on the uncertain information available - provided its immediate and most obvious causes. But because the crucial event occurred just two days before the Armero emergency management plan was to be critically examined and improved, the numerous circumstances which delayed progress of emergency management over the previous year also may be said to have

  16. An unexpected effect of TNF-α on F508del-CFTR maturation and function

    PubMed Central

    Bitam, Sara; Urbach, Valérie; Sermet-Gaudelus, Isabelle; Hinzpeter, Alexandre; Edelman, Aleksander

    2015-01-01

    Cystic fibrosis (CF) is a multifactorial disease caused by mutations in the cystic fibrosis transmembrane conductance regulator gene ( CFTR), which encodes a cAMP-dependent Cl - channel. The most frequent mutation, F508del, leads to the synthesis of a prematurely degraded, otherwise partially functional protein. CFTR is expressed in many epithelia, with major consequences in the airways of patients with CF, characterized by both fluid transport abnormalities and persistent inflammatory responses. The relationship between the acute phase of inflammation and the expression of wild type (WT) CFTR or F508del-CFTR is poorly understood. The aim of the present study was to investigate this effect. The results show that 10 min exposure to TNF-alpha (0.5-50ng/ml) of F508del-CFTR-transfected HeLa cells and human bronchial cells expressing F508del-CFTR in primary culture (HBE) leads to the maturation of F508del-CFTR and induces CFTR chloride currents. The enhanced CFTR expression and function upon TNFα is sustained, in HBE cells, for at least 24 h. The underlying mechanism of action involves a protein kinase C (PKC) signaling pathway, and occurs through insertion of vesicles containing F508del-CFTR to the plasma membrane, with TNFα behaving as a corrector molecule. In conclusion, a novel and unexpected action of TNFα has been discovered and points to the importance of systematic studies on the roles of inflammatory mediators in the maturation of abnormally folded proteins in general and in the context of CF in particular. PMID:26594334

  17. Haplotype analysis of the 185delAG BRCA1 mutation in ethnically diverse populations

    PubMed Central

    Laitman, Yael; Feng, Bing-Jian; Zamir, Itay M; Weitzel, Jeffrey N; Duncan, Paul; Port, Danielle; Thirthagiri, Eswary; Teo, Soo-Hwang; Evans, Gareth; Latif, Ayse; Newman, William G; Gershoni-Baruch, Ruth; Zidan, Jamal; Shimon-Paluch, Shani; Goldgar, David; Friedman, Eitan

    2013-01-01

    The 185delAG* BRCA1 mutation is encountered primarily in Jewish Ashkenazi and Iraqi individuals, and sporadically in non-Jews. Previous studies estimated that this is a founder mutation in Jewish mutation carriers that arose before the dispersion of Jews in the Diaspora ∼2500 years ago. The aim of this study was to assess the haplotype in ethnically diverse 185delAG* BRCA1 mutation carriers, and to estimate the age at which the mutation arose. Ethnically diverse Jewish and non-Jewish 185delAG*BRCA1 mutation carriers and their relatives were genotyped using 15 microsatellite markers and three SNPs spanning 12.5 MB, encompassing the BRCA1 gene locus. Estimation of mutation age was based on a subset of 11 markers spanning a region of ∼5 MB, using a previously developed algorithm applying the maximum likelihood method. Overall, 188 participants (154 carriers and 34 noncarriers) from 115 families were included: Ashkenazi, Iraq, Kuchin-Indians, Syria, Turkey, Iran, Tunisia, Bulgaria, non-Jewish English, non-Jewish Malaysian, and Hispanics. Haplotype analysis indicated that the 185delAG mutation arose 750–1500 years ago. In Ashkenazim, it is a founder mutation that arose 61 generations ago, and with a small group of founder mutations was introduced into the Hispanic population (conversos) ∼650 years ago, and into the Iraqi–Jewish community ∼450 years ago. The 185delAG mutation in the non-Jewish populations in Malaysia and the UK arose at least twice independently. We conclude that the 185delAG* BRCA1 mutation resides on a common haplotype among Ashkenazi Jews, and arose about 61 generations ago and arose independently at least twice in non-Jews. PMID:22763381

  18. Development and Utilization of InDel Markers to Identify Peanut (Arachis hypogaea) Disease Resistance

    PubMed Central

    Liu, Lifeng; Dang, Phat M.; Chen, Charles Y.

    2015-01-01

    Peanut diseases, such as leaf spot and spotted wilt caused by Tomato Spotted Wilt Virus, can significantly reduce yield and quality. Application of marker assisted plant breeding requires the development and validation of different types of DNA molecular markers. Nearly 10,000 SSR-based molecular markers have been identified by various research groups around the world, but less than 14.5% showed polymorphism in peanut and only 6.4% have been mapped. Low levels of polymorphism limit the application of marker assisted selection (MAS) in peanut breeding programs. Insertion/deletion (InDel) markers have been reported to be more polymorphic than SSRs in some crops. The goals of this study were to identify novel InDel markers and to evaluate the potential use in peanut breeding. Forty-eight InDel markers were developed from conserved sequences of functional genes and tested in a diverse panel of 118 accessions covering six botanical types of cultivated peanut, of which 104 were from the U.S. mini-core. Results showed that 16 InDel markers were polymorphic with polymorphic information content (PIC) among InDels ranged from 0.017 to 0.660. With respect to botanical types, PICs varied from 0.176 for fastigiata var., 0.181 for hypogaea var., 0.306 for vulgaris var., 0.534 for aequatoriana var., 0.556 for peruviana var., to 0.660 for hirsuta var., implying that aequatoriana var., peruviana var., and hirsuta var. have higher genetic diversity than the other types and provide a basis for gene functional studies. Single marker analysis was conducted to associate specific marker to disease resistant traits. Five InDels from functional genes were identified to be significantly correlated to tomato spotted wilt virus (TSWV) infection and leaf spot, and these novel markers will be utilized to identify disease resistant genotype in breeding populations. PMID:26617627

  19. Haplotype analysis of the 185delAG BRCA1 mutation in ethnically diverse populations.

    PubMed

    Laitman, Yael; Feng, Bing-Jian; Zamir, Itay M; Weitzel, Jeffrey N; Duncan, Paul; Port, Danielle; Thirthagiri, Eswary; Teo, Soo-Hwang; Evans, Gareth; Latif, Ayse; Newman, William G; Gershoni-Baruch, Ruth; Zidan, Jamal; Shimon-Paluch, Shani; Goldgar, David; Friedman, Eitan

    2013-02-01

    The 185delAG* BRCA1 mutation is encountered primarily in Jewish Ashkenazi and Iraqi individuals, and sporadically in non-Jews. Previous studies estimated that this is a founder mutation in Jewish mutation carriers that arose before the dispersion of Jews in the Diaspora ~2500 years ago. The aim of this study was to assess the haplotype in ethnically diverse 185delAG* BRCA1 mutation carriers, and to estimate the age at which the mutation arose. Ethnically diverse Jewish and non-Jewish 185delAG*BRCA1 mutation carriers and their relatives were genotyped using 15 microsatellite markers and three SNPs spanning 12.5 MB, encompassing the BRCA1 gene locus. Estimation of mutation age was based on a subset of 11 markers spanning a region of ~5 MB, using a previously developed algorithm applying the maximum likelihood method. Overall, 188 participants (154 carriers and 34 noncarriers) from 115 families were included: Ashkenazi, Iraq, Kuchin-Indians, Syria, Turkey, Iran, Tunisia, Bulgaria, non-Jewish English, non-Jewish Malaysian, and Hispanics. Haplotype analysis indicated that the 185delAG mutation arose 750-1500 years ago. In Ashkenazim, it is a founder mutation that arose 61 generations ago, and with a small group of founder mutations was introduced into the Hispanic population (conversos) ~650 years ago, and into the Iraqi-Jewish community ~450 years ago. The 185delAG mutation in the non-Jewish populations in Malaysia and the UK arose at least twice independently. We conclude that the 185delAG* BRCA1 mutation resides on a common haplotype among Ashkenazi Jews, and arose about 61 generations ago and arose independently at least twice in non-Jews. PMID:22763381

  20. D469del-COMP retention in chondrocytes stimulates caspase-independent necroptosis.

    PubMed

    Coustry, Françoise; Posey, Karen L; Liu, Peiman; Alcorn, Joseph L; Hecht, Jacqueline T

    2012-02-01

    Mutations in the cartilage oligomeric matrix protein gene (COMP) cause pseudoachondroplasia (PSACH). This dysplasia results from the intracellular retention of mutant COMP protein and premature death of growth-plate chondrocytes. Toward better understanding of these underlying mechanisms, we examined D469del-COMP activation of the unfolded protein response and cell death pathways in rat chondrosarcoma cells. Using an inducible expression system, we examined the effects of D469del-COMP retention after 4 days of mRNA expression and then 5 days without inducing agent. Retention of D469del-COMP stimulated Chop (Ddit3) and Gadd34 (Ppp1r15a) and triggered reactivation of protein translation that exacerbated intracellular retention. High levels of Nox4 and endoplasmic reticulum receptor stress-inducible Ero1β generated reactive oxygen species, causing oxidative stress. Increased expression of Gadd genes and presence of γH2AX indicated that DNA damage was occurring. The presence of cleaved apoptosis inducing factor (tAIF) and the absence of activated caspases indicated that retention of D469del-COMP triggers cell death in chondrocytes by necroptosis, a caspase-independent programmed necrosis. Loss of growth-plate chondrocytes by necroptosis was also found in our pseudoachondroplasia mouse model. These results suggest a model in which D469del-COMP expression induces persistent endoplasmic reticulum stress, oxidative stress, and DNA damage, thus priming chondrocytes for necroptosis. We define for the first time the precise mechanisms underlying D469del-COMP pathology in pseudoachondroplasia and suggest that oxidative stress and AIF may be promising therapeutic targets. PMID:22154936

  1. Development of EST-based SNP and InDel markers and their utilization in tetraploid cotton genetic mapping

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Expressed sequence tags (ESTs) were analyzed in silico in order to identify single nucleotide polymorphisms (SNPs) and insertion-deletion polymorphisms (InDels) in cotton. A total of 1349 EST-based SNP and InDel markers were developed by comparing ESTs between Gossypium hirsutum and G. barbadense, m...

  2. DELIVERING TIMELY AIR QUALITY, TRAFFIC, AND WEATHER INFORMATION TO YOUR COMMUNITY/THE PASO DEL NORTE ENVIRONMENTAL MONITORING PROJECT

    EPA Science Inventory

    EPA has developed a technology transfer handbook for the EMPACT Paso del Norte Project. The EMPACT Paso del Norte Environmental Monitoring Project is a mobile vehicle emissions project that involves the international community of El Paso, TX; Sundland Park, NM; and Juarez, Mexico...

  3. 75 FR 44720 - Safety Zone; Live-Fire Gun Exercise, M/V Del Monte, James River, VA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-29

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Live-Fire Gun Exercise, M/V Del Monte... specified waters of the James River to protect mariners from the hazards associated with live fire and... conduct a live fire and explosive training event onboard the M/V Del Monte in the vicinity of the...

  4. Resultado negativo de prueba del VPH es mejor predictor de riesgo bajo de cáncer de cuello uterino

    Cancer.gov

    De acuerdo con un estudio en el que participaron más de un millón de mujeres, los investigadores del NCI han determinado que el resultado negativo de una prueba para la detección del VPH proporciona mayor certeza o seguridad frente a riesgos futuros de cá

  5. Do crustal deformations observed by GPS in Tierra del Fuego (Argentina) reflect glacial-isostatic adjustment?

    NASA Astrophysics Data System (ADS)

    Mendoza, L.; Richter, A.; Hormaechea, J. L.; Perdomo, R.; Del Cogliano, D.; Dietrich, R.; Fritsche, M.

    2010-09-01

    Vertical site velocities determined by geodetic GPS observations in the Lago Fagnano area, Tierra del Fuego main island, are interpreted with respect to their potential relation with the glacial-isostatic crustal response to ice mass changes. The spatial pattern of the uplift rates, in combination with the horizontal crustal deformation pattern, point towards a fault-tectonic rather than glacial-isostatic origin of the determined vertical crustal deformations. This implies rather small GIA effects pointing towards relatively small Holocene ice-mass changes in Tierra del Fuego. However, these findings are considered to be preliminary. They should be confirmed by additional observations covering an extended area with GPS sites.

  6. Historical survey of the national astronomical observatory in Llano del Hato

    NASA Astrophysics Data System (ADS)

    Martinez Picar, Antonio; Salas Ramirez, Henry

    2007-12-01

    The Centro de Investigaciones de Astronomia (CIDA), the Venezuelan Institute in charge for managing human- and technical resources of the National Astronomical Observatory in Llano del Hato, is one of the younger institutes in its field. However, its foundation is surrounded by a series of curious and interesting eyents that go back to the end of the 18th century. Its equatoriallocation, excellent astronomical equipment and the high-qualified personnel offers a geographical and technical advantage. The paper is a historical oveniew of events, facts and demonstrations of the human activity related to the conception, building and starting the Llano del Hato National Astronomical Observatory.

  7. Matrix frequency analysis and its applications to language classification of textual data for English and Hebrew

    NASA Astrophysics Data System (ADS)

    Uchill, Joseph H.; Assadi, Amir H.

    2003-01-01

    The advent of the internet has opened a host of new and exciting questions in the science and mathematics of information organization and data mining. In particular, a highly ambitious promise of the internet is to bring the bulk of human knowledge to everyone with access to a computer network, providing a democratic medium for sharing and communicating knowledge regardless of the language of the communication. The development of sharing and communication of knowledge via transfer of digital files is the first crucial achievement in this direction. Nonetheless, available solutions to numerous ancillary problems remain far from satisfactory. Among such outstanding problems are the first few fundamental questions that have been responsible for the emergence and rapid growth of the new field of Knowledge Engineering, namely, classification of forms of data, their effective organization, and extraction of knowledge from massive distributed data sets, and the design of fast effective search engines. The precision of machine learning algorithms in classification and recognition of image data (e.g. those scanned from books and other printed documents) are still far from human performance and speed in similar tasks. Discriminating the many forms of ASCII data from each other is not as difficult in view of the emerging universal standards for file-format. Nonetheless, most of the past and relatively recent human knowledge is yet to be transformed and saved in such machine readable formats. In particular, an outstanding problem in knowledge engineering is the problem of organization and management--with precision comparable to human performance--of knowledge in the form of images of documents that broadly belong to either text, image or a blend of both. It was shown in that the effectiveness of OCR was intertwined with the success of language and font recognition.

  8. Developing the Textual Turn: Tracking the Grammar of Research Case Records

    ERIC Educational Resources Information Center

    Thomson, Pat

    2005-01-01

    During action research projects a great deal of written material is produced. Some of this is data generated about the project, some about the process of the research and some is reflective writing about the researcher(s). In this article I propose that a deliberate focus on the tracking of texts might be helpful in action research, particularly…

  9. "Hey, I Didn't Say That!": Teaching Textual Integrity through Misrepresented Quotes

    ERIC Educational Resources Information Center

    Ford, Jessica L.

    2015-01-01

    Despite specialized areas of expertise, communication instructors are unified, to a large extent, by a singular belief: the meaning people give words produces behavioral ramifications (Mead, 2009). Communication instructors revere language's ability to reflect both meaning and reality. Yet, they also are tasked with the responsibility of conveying…

  10. Young Children's Meaning-Making through Drawing and "Telling": Analogies to Filmic Textual Features

    ERIC Educational Resources Information Center

    Wright, Susan

    2007-01-01

    Young children's meaning-making is a multifaceted, complex experience, where thought, body and emotion unite. Rich and intricate creations are brought to life through children's formation, communication and interpretation of "signs" which stand for or represent something else. The term drawing-telling is used to describe children's use of a range…

  11. BAAL/CUP Seminars 2013/Text Trajectories--Developing Dynamic Approaches to Textual Analysis

    ERIC Educational Resources Information Center

    Maybin, Janet; Lillis, Theresa

    2015-01-01

    This seminar took place on 19 April, 2013 at the Centre for Language and Communication, Faculty of Language and Education Studies, The Open University. The seminar was coordinated by Janet Maybin and Theresa Lillis and there were 28 participants, including four postgraduate students, from universities in Britain, Belgium and South Africa.

  12. Understanding Textual Authorship in the Digital Environment: Lessons from Historical Perspectives

    ERIC Educational Resources Information Center

    Velagic, Zoran; Hasenay, Damir

    2013-01-01

    Introduction: The paper explains how the modern understanding of authorship developed and sets out the problems to be considered when discussing digital authorship. Method: The contextual analysis of contents of the key themes is employed; in the articulation of the conclusions, analytic and synthetic approaches are used. Results: At each turning…

  13. Texts as Mirrors, Texts as Windows: Black Adolescent Boys and the Complexities of Textual Relevance

    ERIC Educational Resources Information Center

    Sciurba, Katie

    2015-01-01

    Discussions of culturally relevant and "boy" literature stress the importance of offering readers occasions to see themselves in texts. However, young men of color have had few opportunities within this discourse to reveal their own experiences with literature. Rather than make presumptions about how texts serve as mirrors to them, as…

  14. Textual Orientations: Gay and Lesbian Students and the Making of Discourse Communities.

    ERIC Educational Resources Information Center

    Gulla, Amanda Nicole

    For Peter Elbow, a writing classroom should be an opportunity for students to tell their stories to a community in which everyone is safe to take risks, and all support each other in the development of their expressive skills. To be "other," however, is always a scary thing. The lesbian, gay, or bisexual writing student is usually seen as having a…

  15. Undocumented in a Documentary Society: Textual Borders and Transnational Religious Literacies

    ERIC Educational Resources Information Center

    Vieira, Kate

    2011-01-01

    While transnationalism has emerged as a growing area of interest in Writing Studies, the field has not fully examined how migrants' movement across national borders shapes their literacy practices. This article offers one answer to this question by reporting on an ethnographic study of the transnational religious literacies of a community of…

  16. A Multi-Perspective Genre Analysis of the Barrister's Opinion: Writing Context, Generic Structure, and Textualization

    ERIC Educational Resources Information Center

    Hafner, Christoph A.

    2010-01-01

    In teaching and researching English for Law, considerable effort has been put into the fine-grained description of legal genres and accounts of associated legal literacy practices. Much of this work has been carried out in the academic context, focusing especially on genres encountered by undergraduate law students. The range of genres which must…

  17. [Textual research on Huang shinüke (Huang's Obstetrics and Gynecology)].

    PubMed

    Wen, Jianfang; Wu, Tong

    2015-07-01

    Huang shi nü ke (Huang's Obstetrics and Gynecology), a handwritten copy of the Ming Dynasty passed on by Huang Xiaoyou, Yuanyi and Huang Dongjiu, and sorted out by Huang Yanrong, was a family medical book of Huang's obstetrics and gynecology in Xin'an, being a summary of their clinical experience.There were altogether 44 chapters divided into 4 parts, including general introduction, general principle of treatment, discussions on prenatal conditions and qi acquired from the mother, and gynecological diseases in sequence, with the appendixes of pulse diagnostics for differentiating male and female, and the 10-month methods of protecting the fetus. PMID:26815029

  18. [Textual research on Amara (Mangifera Indica Linn), Butea monsperma (Lam) Kuntze, and Ferula asatoitida L].

    PubMed

    Li, Zhaohua; Wang, Yulin

    2015-01-01

    In the Buddhist canons, there are lots of medicines imported from abroad recorded. The dictionary works of such Buddhist canons give detailed annotations and explanations to all these foreign medicines, from which we can investigate the features of all these medicines. It is also clear that these three medicines were imported into China no later than the Tang Dynasty. Amara was originally grown in the xi yu (Western Region) , now called Mango. Its form and connotation appeared no later than the eastern Han Dynasty, and the explanation of this medicine appears in the A Great Modern Dictionary of Chinese is wrong. While its explanation for Butea monsperma should be supplemented. There are two kinds of asafoitida, herbaceous and woody. Only the former one is used for medical purpose, and the annotation appeared in A Great Modern Dictionary of Chinese is problematic. PMID:26268251

  19. [Textual research on circulation of the Ming edition of Li Heng's Xiu zhen fang (Pocket Formulary)].

    PubMed

    Yang, Jinping; Liu, Peng; Lu, Mingjing; Lu, Xing; Li, Shaolin; Jin, Xiumei

    2015-03-01

    Xiu zhen fang (Pocket Formulary) is a recipe book of the Ming Dynasty, inspired and managed by Zhu Su, compiled by Li Heng of liangyisuo (good physician house) in Zhou wangfu (Zhou's royal palace). The book was compiled and published twice during the reigns of the Hongwu and Yongle Emperors of the Ming Dynasty. Because of its high practicability, there were some editions in circulation, and the book was published several times only in the Ming Dynasty. At present, the earliest extanteditionwas the little character version of Yongle, and the version in the 4(th) year of Zhengde Emperor of the Ming Dynasty was a reprinting edition based on the Yongle edition, sharingthe same edition system. Most of the editions appeared after the reign of Zhengtong Emperor of the Ming Dynasty, titled by "kui ben (head version)" and "da quan (complete edition)" were the editionspublished in the local bookshops, which had rather distinct differences from the Yongle edition system not only in the its format but also in its contents. PMID:26420414

  20. Power Relationships in Rumpelstiltskin: A Textual Comparison of a Traditional and a Reconstructed Fairy Tale

    ERIC Educational Resources Information Center

    Kelley, Jane E.

    2008-01-01

    Reconstructed fairy tales provide a different point of view and challenge the assumptions of a common set of values; for that reason, these stories provide a medium in which to examine power relationships in texts by applying a critical multicultural analysis (Botelho & Rudman, forthcoming, 2008, "A critical multicultural analysis of children's…

  1. Mining for Meaning: The Use of Unstructured Textual Data in Information Systems Research

    ERIC Educational Resources Information Center

    Triplett, Janea Lynne

    2012-01-01

    The objectives of this research are to demonstrate how text was used in (1) developing a theory to examine collaborative interaction in virtual worlds, (2) creating a framework for improving the efficiency and effectiveness of dealing with large text datasets for social network analysis, and (3) approaching an understanding of the role of meaning…

  2. Extraction of chemical-induced diseases using prior knowledge and textual information.

    PubMed

    Pons, Ewoud; Becker, Benedikt F H; Akhondi, Saber A; Afzal, Zubair; van Mulligen, Erik M; Kors, Jan A

    2016-01-01

    We describe our approach to the chemical-disease relation (CDR) task in the BioCreative V challenge. The CDR task consists of two subtasks: automatic disease-named entity recognition and normalization (DNER), and extraction of chemical-induced diseases (CIDs) from Medline abstracts. For the DNER subtask, we used our concept recognition tool Peregrine, in combination with several optimization steps. For the CID subtask, our system, which we named RELigator, was trained on a rich feature set, comprising features derived from a graph database containing prior knowledge about chemicals and diseases, and linguistic and statistical features derived from the abstracts in the CDR training corpus. We describe the systems that were developed and present evaluation results for both subtasks on the CDR test set. For DNER, our Peregrine system reached anF-score of 0.757. For CID, the system achieved anF-score of 0.526, which ranked second among 18 participating teams. Several post-challenge modifications of the systems resulted in substantially improvedF-scores (0.828 for DNER and 0.602 for CID). RELigator is available as a web service athttp://biosemantics.org/index.php/software/religator. PMID:27081155

  3. Textual Concept Critical Analysis: Toward a Research Approach for Language Studies

    ERIC Educational Resources Information Center

    Osborn, Terry A.; Reagan, Timothy G.; Freiberg, Jo Ann

    2011-01-01

    When the International Society for Language Studies (ISLS) was founded in 2002 and the journal that is now "Critical Inquiry in Language Studies (CILS)" was in the planning stages, we recognized a need for an interdisciplinary, or perhaps even transdisciplinary (see Kaufman, Moss, & Osborn, 2003), venue for the publication of research on language…

  4. Writing Material in Chemical Physics Research: The Laboratory Notebook as Locus of Technical and Textual Integration

    ERIC Educational Resources Information Center

    Wickman, Chad

    2010-01-01

    This article, drawing on ethnographic study in a chemical physics research facility, explores how notebooks are used and produced in the conduct of laboratory science. Data include written field notes of laboratory activity; visual documentation of "in situ" writing processes; analysis of inscriptions, texts, and material artifacts produced in the…

  5. The best of both worlds : integrating textual and visual command interfaces for Mars Rover Operations

    NASA Technical Reports Server (NTRS)

    Maxwell, Scott A.; Cooper, Brian; Hartman, Frank; Wright, John; Yen, Jeng; Leger, Chris

    2005-01-01

    A Mars rover is a complex system, and driving one is a complex endeavor. Rover driver must be intimately familiar with the hardware and software of the mobility system and of the robotic arm. They must rapidly assess threats in the terrain, then creatively combine their knowledge o f the vehicle and its environment to achieve each day's science and engineering objective.

  6. Preparing for Opening Night: Temporal Boundary Objects in Textually-Mediated Professional Practice

    ERIC Educational Resources Information Center

    Davies, Elisabeth; McKenzie, Pamela J.

    2004-01-01

    The authors report on two projects in which the role of documents as temporal boundary objects mediating information practices across multiple timelines was explored. It has been suggested that studying workplace documents will uncover the information practices of professionals beyond traditional information needs and uses studies. Two workplaces…

  7. Engineering discovery learning: The contingency adduction of some precursors of textual responding in a beginning program

    PubMed Central

    Layng, T. V. Joe; Twyman, Janet S.; Stikeleather, Greg

    2004-01-01

    A learning situation in which the principal content of what is to be learned is not given but is independently discovered by the learner is often considered “discovery learning.” Recently, learning scientists have been able to make explicit some of the conditions under which such independent discovery is likely to occur (Andronis, 1983; Epstein, 1996; Johnson & Layng, 1992). One form of “discovery” can often be observed when skills learned under one set of conditions are recruited under new conditions to serve a new or different function—a process of “contingency adduction” (Andronis, Layng, & Goldiamond, 1997). The research reported here investigated the application of contingency adduction in a discovery learning context to establish sound-to-letter correspondence as part of an online reading/decoding program, Headsprout Early Reading. Beginning readers acquired novel letters/sounds correspondence with minimal presentations and few errors—often requiring only one presentation. This research suggests that instructional sequences may be designed to provide effective discovery learning activities to teach some phonics skills. PMID:22477292

  8. Extra-Textual Talk in Shared Book Reading: A Focus on Questioning

    ERIC Educational Resources Information Center

    Anderson, Ann; Anderson, Jim; Lynch, Jacqueline; Shapiro, Jon; Kim, Ji Eun

    2012-01-01

    In this study we investigated the frequency and types of questions asked when parents read with their four-year-old children, the relationship between the frequency and types of questions parents and children asked, and the relationship between these and the children's early literacy knowledge. Forty dyads shared two narrative texts and two…

  9. Women and the Scientific Idiom: Textual Episodes from Wollstonecraft, Fuller, Gilman, and Firestone

    ERIC Educational Resources Information Center

    Magner, Lois N.

    1978-01-01

    Concepts that these four feminists had about science as a body of knowledge are quite different due to the time span involved. The modern idea that the human species has outgrown nature separates Firestone from the earlier authors of the classics of feminist thought. (Author/KR)

  10. The Textual Organisation of Research Article Introductions in Applied Linguistics: Variability within a Single Discipline

    ERIC Educational Resources Information Center

    Ozturk, Ismet

    2007-01-01

    This paper explores the degree of variability in the structure of research article introductions within a single discipline. It is an exploratory study based on the analysis of 20 research articles. The study investigates the differences between two subdisciplines of applied linguistics, namely second language acquisition and second language…

  11. Extraction of chemical-induced diseases using prior knowledge and textual information

    PubMed Central

    Pons, Ewoud; Becker, Benedikt F.H.; Akhondi, Saber A.; Afzal, Zubair; van Mulligen, Erik M.; Kors, Jan A.

    2016-01-01

    We describe our approach to the chemical–disease relation (CDR) task in the BioCreative V challenge. The CDR task consists of two subtasks: automatic disease-named entity recognition and normalization (DNER), and extraction of chemical-induced diseases (CIDs) from Medline abstracts. For the DNER subtask, we used our concept recognition tool Peregrine, in combination with several optimization steps. For the CID subtask, our system, which we named RELigator, was trained on a rich feature set, comprising features derived from a graph database containing prior knowledge about chemicals and diseases, and linguistic and statistical features derived from the abstracts in the CDR training corpus. We describe the systems that were developed and present evaluation results for both subtasks on the CDR test set. For DNER, our Peregrine system reached an F-score of 0.757. For CID, the system achieved an F-score of 0.526, which ranked second among 18 participating teams. Several post-challenge modifications of the systems resulted in substantially improved F-scores (0.828 for DNER and 0.602 for CID). RELigator is available as a web service at http://biosemantics.org/index.php/software/religator. PMID:27081155

  12. Critical Health Literacy: Shifting Textual-Social Practices in the Health Classroom

    ERIC Educational Resources Information Center

    Renwick, Kerry

    2014-01-01

    This paper will consider ways in which students are constructed as aliens in health classrooms. Creating the classroom as a setting for health promotion requires closer attention to those who make use of such space. If classrooms are places where diversity exists and is recognised, then health educators are challenged to consider how students are…

  13. The Role Played by the Right Hemisphere in the Organization of Complex Textual Structures

    ERIC Educational Resources Information Center

    Marini, A.; Carlomagno, S.; Caltagirone, C.; Nocentini, U.

    2005-01-01

    Eleven patients with right hemisphere damage (RHD), 11 left hemisphere damaged (LHD) nonaphasic subjects, and 11 neurologically intact controls were given three story description tasks. The two brain-damaged groups had no language, visuospatial, memory, or conceptual deficits on standardized neuropsychological testing. In the first experiment, the…

  14. Is the Frame Broken? Seeking New Metaphors for Textual Study in English

    ERIC Educational Resources Information Center

    McKnight, Lucinda

    2015-01-01

    This article draws from a doctoral study of how female teachers design English curriculum around girls' popular culture in a contemporary coeducational secondary setting and focuses on how English teachers contemplate the study of texts in the space of school-based curriculum planning. The article presents an argument for reflexivity around how we…

  15. [Textual research on the literature sources, its related names and medicinal part of Lonicera japonica Thunb].

    PubMed

    Wang, Peng; Zhou, Yang; Fu, Xian-Jun; Wang, Zhen-Guo

    2013-05-01

    The "jin yin hua" (Lonicera japonica Thunb.) used in the clinic nowadays is the flower of honeysuckle, excluding its stem, leave, branch, vine or the whole plant. In the early time, the name of "ren dong" (honeysuckle) or "ren dong teng" (Caulis lonicerae) didn't refer exclusively to the flower of honeysuckle. A few early literature, such as Xin xiu ben cao (Newly Revised Materia Medica) recorded briefly the flower, yet only mentions its time of blossom and shape without mentioning the medicinal use of its flower, nor the title of "jin yin hua", as the identification for this plant. Therefore, it cannot be regarded as the primary source of "jin yin hua". This research points out that the first appearance of the name of "jin yin hua" should be in Su shen liang fang (Su-Shen's Effective Prescriptions) of the Song Dynasty, and the first usage of the flower "jin yin hua" as a single drug was in Wai ke jing yao (Essence of External Diseases) of the Song Dynasty. Thus, the conclusion that "jin yin hua" is first seen in Xin xiu ben cao or lv chan yan ben cao (Mountainous Materia Medica) quoted in the ninth edition of teaching material of Traditional Chinese Pharmacology, and Chinese Materia Medica are all wrong and should be corrected accordingly. PMID:24060026

  16. [Examples of textual research on gynecological literature included in Yong le da dian (Yongle's Great Canon)].

    PubMed

    Zhang, Xue-dan; Zhang, Ru-qing

    2010-07-01

    Yongle's Great Canon is a series of books to be read exclusively by the emperors of the Ming Dynasty, so all of the books included are from many rare books collected in Wen Yuan Ge of early Ming Dynasty. These rare books, ranging from Song, Jin, and Yuan Dynasties or from folk sources preserve the original appearance of the ancient books almost without any changes. From a philological viewpoint, the gynecological books included in Yong le da dian are studied, proof-read and checked for its lost texts and different texts. This can serve as a basis for the reprinting and re-publishing of ancient TCM books. PMID:21122346

  17. [Herbal textual research on origin and development of traditional Chinese medicine "duhuo" and "qianghuo"].

    PubMed

    Shan, Feng; Yuan, Yuan; Hao, Jin-Da; Huang, Lu-Qi

    2014-09-01

    To clarify the origin and development of the traditional Chinese medicine "Duhuo" and "Qianghuo" with medicinal literatures. Medical literatures of past dynasties were analysed and combined with the modern material. The "Duhuo" in Herbal writing Shen Nong Ben Cao Jing include traditional Chinese medicine "Duhuo" and "Qianghuo", "Qianghuo" was separated from "Duhuo" due to the distinguish of clinical application. The origin of "Qianghuo" is Notopterygium incisum and N. forbesii, However, The origin of "Duhuo" is very complex, Angelica pubescens f. biserrata as authentic "Duhuo" was used from Song Dynasty. "Qianghuo" was originated from "Duhuo". PMID:25522638

  18. [The textual research on FANG Dao's life and Fangshijiacangjiyaofang (Collected prescription of Fang family's).].

    PubMed

    Fu, Jian-Zhong

    2009-11-01

    Fangshijiacangjiyaofang (Collected prescription of Fang family's) is a prescription book compiled by Fang Dao in Southern Song Dynasty, and most of these prescriptions from experience have important clinical guiding values. However, few recorders about the book and its compiler could be found in relevant literature, it is necessary for them to be further verified. PMID:20193449

  19. Patterns of Enquiry: Textual Analysis of a Classroom Discussion Unit on Bee Feeding Behaviour.

    ERIC Educational Resources Information Center

    Binns, Richard W.

    This paper constitutes an analysis of "Honey Bee Communication: An Enquiry into Two Concepts of Animal Behavior," a unit of classroom discussion modules developed by the Patterns of Enquiry Project at the Ontario Institute for Studies in Education. The conceptual framework of the analysis consists of four major items: (1) descriptive…

  20. Effects of textual cue manipulation on student recall in an information mapped nutrition text.

    PubMed

    Tanenbaum, B G; Tillman, M H

    1990-05-01

    Using the subject area of nutrition, this study examined the effects of different instructional features of an adjunctive text for nursing students who varied in reading level. Specifically, the study investigated the effects of both variations in instructional features of information-mapped text and the differences in student reading levels on immediate recall scores and work time spent on the modules. A sample of 65 nursing students was classified into high and low reading groups according to the Nelson-Denny Reading Test, then randomly assigned to one of the three treatment groups. Analysis of covariance indicated significant treatment effects after adjusting the recall scores for the influence of verbal aptitude. Information-mapped text with either postquestions or postquestions and feedback yielded higher recall scores than information-mapped text alone. Subjects whose modules contained postquestions or postquestions and feedback spent significantly more work time than subjects whose modules did not contain those features; however, when the recall scores were adjusted for the influence of work time spent on the modules, there were no significant differences. Conclusions and recommendations for the text construction process, especially for the adjunctive nursing text, are presented. PMID:2162930

  1. Textual Encounters of Three Kinds: Engaging in Reading through Community Astronomy Night

    ERIC Educational Resources Information Center

    Johnson, Amy Suzanne; Rezak, Achariya Tanya; Hodges, Georgia; Lawrence, Molly; Tippins, Deborah; Bongkotphet, Thitiya

    2008-01-01

    This article describes a community science night as a professional development experience for teachers in a rural school in the southeastern United States. As participants circulated through eight astronomy activities, they engaged in reading images, reading writing, and reading their natural and physical world. Through such diverse textual…

  2. Textual and Discoursal Resources Used in the Essay Genre in Sociology and English

    ERIC Educational Resources Information Center

    Bruce, Ian

    2010-01-01

    Research that has examined university assignment writing has varied from large-scale, inventorial surveys across disciplines to more specific, finer-grained analyses of the assignment requirements of specific disciplines. However, while such research has involved surveys of the views and expectations of faculty or the analysis of assignment tasks,…

  3. [The textual research on the evolution of the toothbrush shape in ancient China].

    PubMed

    Wu, Qiu-Peng

    2012-05-01

    Archaeological discovery demonstrates that the ancient plant hair brush first appeared in the Tang dynasty. According to the evolution of the shape of the head and handle of the toothbrush in ancient times, we can divide the evolution of the shapes into three major stages of development: (1) the Tang and the Five dynasties; (2) the Liao, Song, Jin, Yuan dynasties; (3) Ming, Qing and the Republic periods. The toothbrush heads and handles had no significant differences during the Tang and the Five dynasties. However, the shapes of them in the Liao, Song, Jin, Yuan dynasties are somewhat different. In the Ming and Qing and the republic of China periods, the shape of toothbrush head and handle had further refinement. Recently, some scholars raised doubts about the "plant hair toothbrush doctrine". They believe that the archaeological bone graft handle brush was used to wipe hair oil or clean water when washing and dressing. However, according to shape and function and ancient literature records, the archaeological bone graft handle brush should be a plant hair toothbrush used to clean and protect teeth. PMID:22883376

  4. [Textual research on the fire needle and the fire needle therapy].

    PubMed

    Liu, T; Zhu, J P; Zhang, Q C

    2016-03-01

    There are different names of the fire needle therapy in the Huang di nei jing (Inner Canon of Huangdi) such as Zu-zhen (), Cui-zhen (,), Fan-zhen (), Huo-cui (), Cui (,,), Cuici ,), Fan zhen jie ci (). It is claimed that the lance needle, the round sharp needle and the long needle recorded in this Classic are puncturing tools for the fire needle therapy. In the Eastern Han Dynasty, Zhang Zhongjing expanded the indications for the fire needle therapy and Huo-zhen () firstly appeared in the Jin kui yu han jing(Classic of the Jade Box and Golden Chamber). The application of the fire needle therapy had been further expanded to a lot of internal and external disorders form the Wei-Jin-Southern and Northern Dynasties to the Ming and Qing Dynasties. There are more detailed records on the manipulation and the tools of the fire needle therapy during this period. In the 1970s, Huo zhen liao fa () was proposed and still in use today. However the Bai-zhen (plain needle) in ancient literature is equal to the filiform needle and should not be regarded as the former name of the fire needle. PMID:27255194

  5. [Textual research of existing block-printed edition of Source of Acupuncture and Moxibustion (Zhenjiu Fengyuan)].

    PubMed

    Soldan, Jan; Ren, Yu-Lan; Zou, Peng; Liang, Fan-Rong

    2013-08-01

    Based on comprehensive arrangement and analysis of edition origin and development, system, characteristic, archive holding situation of Zhenjiu Fengyuan (Source of Acupuncture and Moxibustion writlen) by LI Xue-chuan in Qing dynasty, the error and mistakes in Summary of TCM Ancient books in China, Union Catalog of TCM Books and Grand Chinese Dictionary of Medical Books are pointed out. On the other hand, under full evaluation and comparison among three types of block-printed editions, Dihua Caotang edition in 2 years of Daoguang emperor, Qing Dynasty (about 1822) that is collected in the library of Beijing University of CM is considered as good edition. PMID:24195227

  6. [Textual research on adulteration of Chinese materia medica in ancient China].

    PubMed

    Xie, Jin; Wang, De-Qun

    2013-09-01

    By investigating the mainstream works of herbal classics of successive ages, it is found that adulteration of Chinese materia medica appeared early in ancient China. The main methods of adulteration was producing fraud medicines in the Northern-Southern Dynasties, fake medicines began to appear in the Tang Dynasty, and status of adulteration of Chinese materia medica ran unchecked since the Ming and Qing Dynasty. By statistics, there were 76 kinds of adulteration varieties before the Republican period. The main varieties were precious drugs, animal drugs and artifacts. Commonly methods used in the process included forging and adulterating, dealing with 11 kinds and 68 kinds respectively. Adulteration probably lead to the result of imposing the changes of the used medicinal parts of Herba Pogostemonis; Radix Aconiti Lateralis prepared by adding salt, Radix Angelica Sinensis processed by wine, and Radix Astragalis seu Hedysaris processed with bee honey. However, the root cause of adulteration in Chinese materia medica was the dissociation of professional physician and pharmacist, resulting in the ignorance of medical practitioners became unable to recognize Chinese materia medica; and the immorality of medicinal merchants. Besides, rating the quality of materia medica based on its producing areas without differentiating the false from the genuine may also contribute to this result passively. PMID:24429032

  7. [Textual research on Capital's Puji Tang (Relief Houses) in the Qing Dynasty].

    PubMed

    Zhang, Lei; Liang, Jun

    2010-05-01

    Puji Tang (Relief Houses) was established in 1706 with the function of helping the poor, comforting and compensating people by medicine, therefore, which was supported by the Emperors of the Qing Dynasty. As a representation of medical relief organization of the Qing Dynasty, Puji Tang was developed from a folk relief organization to a government national organization. Because of the declination of the Qing Empire and the problems within its own organization, Puji Tang changed finally to an organization of reeducation through labor in 1907. PMID:21029716

  8. [Textual research on the illustrations in ancient versions of Yi jin jing (Classic of Changing Tendon)].

    PubMed

    Zhang, Zhibin

    2015-09-01

    For a long time, the origin of inheritance of Daoyin illustrations for changing the tendon and its development are vague and lack of investigation. By investigating 48 kinds of versions of Yi jin jing (Classic of Changing Tendon), and other archaic texts of Daoyin for keeping-fit, it can be identified that there are no illustrations in extant early works of Yi jin jing. In terms of the Daoyin illustrations in the rather extensively distributed Yi jin jing, there are external exercise of Eight Section Brocade, Twelve Illustrations for Changing Tendon, 22-style yi jin jing, which are 3 different series of exercise in which the 22-style is not derived from the 12-style one. The illustrations of Daoyin for changing the tendon in the ancient versions of Yi jin jing were stemmed from the source other than the versions of Yi jin jing itself. Among them, the external exercise of Eight-section brocade is derived from many works of the Ming Dynasty, while the 12 illustrations for changing the tendon is derived from Wei sheng yao shu (Essential Art of Healthcare) in the 18th year of Xianfeng reign of the Qing Dynasty. The so-called "illustrations of external classic of yi jin jing" is but only part of the 22-style yi jin jing. PMID:26813095

  9. Reading and Seeing Themselves: Boys of Color and Textual (Non-)Connection

    ERIC Educational Resources Information Center

    Sciurba, Katie

    2011-01-01

    The discourse on multicultural literature has focused on providing children of color opportunities to "see themselves" in the texts they read. Since the 1920s, advocates like W.E.B. DuBois have stressed that "visibility" in literature fosters positive psychological development among underrepresented groups of children, in addition to promoting…

  10. Contourlet Textual Features: Improving the Diagnosis of Solitary Pulmonary Nodules in Two Dimensional CT Images

    PubMed Central

    Wang, Jingjing; Sun, Tao; Gao, Ni; Menon, Desmond Dev; Luo, Yanxia; Gao, Qi; Li, Xia; Wang, Wei; Zhu, Huiping; Lv, Pingxin; Liang, Zhigang; Tao, Lixin; Liu, Xiangtong; Guo, Xiuhua

    2014-01-01

    Objective To determine the value of contourlet textural features obtained from solitary pulmonary nodules in two dimensional CT images used in diagnoses of lung cancer. Materials and Methods A total of 6,299 CT images were acquired from 336 patients, with 1,454 benign pulmonary nodule images from 84 patients (50 male, 34 female) and 4,845 malignant from 252 patients (150 male, 102 female). Further to this, nineteen patient information categories, which included seven demographic parameters and twelve morphological features, were also collected. A contourlet was used to extract fourteen types of textural features. These were then used to establish three support vector machine models. One comprised a database constructed of nineteen collected patient information categories, another included contourlet textural features and the third one contained both sets of information. Ten-fold cross-validation was used to evaluate the diagnosis results for the three databases, with sensitivity, specificity, accuracy, the area under the curve (AUC), precision, Youden index, and F-measure were used as the assessment criteria. In addition, the synthetic minority over-sampling technique (SMOTE) was used to preprocess the unbalanced data. Results Using a database containing textural features and patient information, sensitivity, specificity, accuracy, AUC, precision, Youden index, and F-measure were: 0.95, 0.71, 0.89, 0.89, 0.92, 0.66, and 0.93 respectively. These results were higher than results derived using the database without textural features (0.82, 0.47, 0.74, 0.67, 0.84, 0.29, and 0.83 respectively) as well as the database comprising only textural features (0.81, 0.64, 0.67, 0.72, 0.88, 0.44, and 0.85 respectively). Using the SMOTE as a pre-processing procedure, new balanced database generated, including observations of 5,816 benign ROIs and 5,815 malignant ROIs, and accuracy was 0.93. Conclusion Our results indicate that the combined contourlet textural features of solitary pulmonary nodules in CT images with patient profile information could potentially improve the diagnosis of lung cancer. PMID:25250576

  11. A Textual Research on the First Private University in Modern China

    ERIC Educational Resources Information Center

    Tian, Zhengping; Chen, Taolan

    2008-01-01

    Recently there have been many viewpoints as to which private university was founded firstly in modern China. The schools, such as Fudan University (or the former Aurora Academy), Nankai University, China College, Wuchang Zhonghua University, Nanyang College and Zhengmeng Academy are all considered to be the first private university. From two…

  12. The Effect of Explicit Instruction of Textual Discourse Markers on Saudi EFL Learners' Reading Comprehension

    ERIC Educational Resources Information Center

    Al-Qahtani, Abdulaziz Ali

    2015-01-01

    Discourse markers (DMs) instruction is currently receiving an increasing amount of attention in the literature on second language learning. As noted by Al-Yaari, Al Hammadi, Alyami, and Almaflehi (2013), and Algouzi (2014), the use of DMs is insufficient to support the development of the language skills, especially reading, of Saudi English as a…

  13. Students' Behaviors and Views of Paraphrasing and Inappropriate Textual Borrowing in an EFL Academic Setting

    ERIC Educational Resources Information Center

    Liao, Ming-Tzu; Tseng, Chiung-Ying

    2010-01-01

    This study examines skillful EFL writers' and less skillful writers' EFL performance and perceptions of paraphrasing and inappropriate text borrowing, the extent to which their performance matches perceptions, and the factors behind their problematic text borrowing. Ninety-five postgraduates and undergraduates in Taiwan accomplished a paraphrasing…

  14. [Historical textual research on Shan biandou with discussion on the misnaming of plant title].

    PubMed

    Li, J B

    2016-05-01

    The original plants of Shan biandou, first seen in Jiu huang ben cao (Materia Medica for Relief of Famines), include the plants of Astragalusgenus, such as A. scaberrimus and/or A. complanatus in the Ming and Qing Dynasties. But Cassia mimosoides was named as Shan biandou by Japanese scholars in the 19th century. This mistaken identification and misnaming, still in use today in Chinese and Japanese circles of botany and materia medica, did cause some confusion. The merits and demerits of using the plant names in Chinese characters from the Japanese language by Chinese botanists were analyzed, the disadvantages of which should be well avoided. Because of the vicissitude in the names of plants and Chinese herbs, it is necessary to strengthen the study and develop the significant value of A. complanatus and C. mimosoides in health care so as to promote its contributions to the cause of TCM. PMID:27485866

  15. Semantic Development in Textual Contexts during the School Years: Noun Scale Analyses

    ERIC Educational Resources Information Center

    Ravid, Dorit

    2006-01-01

    The paper examines the nominal lexicon in later language acquisition as a window on linguistic knowledge and usage across childhood and adolescence. The paper presents a psycholinguistically motivated and cognitively grounded analysis of the distribution of ten semantic noun categories (the Noun Scale) across development, modality, and genre.…

  16. A Systematic Characterization of Cognitive Techniques for Learning from Textual and Pictorial Representations

    ERIC Educational Resources Information Center

    Ploetzner, Rolf; Lowe, Richard; Schlag, Sabine

    2013-01-01

    Pictorial representations can play a pivotal role in both printed and digital learning material. Although there has been extensive research on cognitive techniques and strategies for learning from text, the same cannot be said for static and dynamic pictorial representations. In this paper we propose a systematic characterization of cognitive…

  17. Reading Repression: Textualizing the Linguistic Marginalization of Nonnative English-Speaking Teachers in Arizona

    ERIC Educational Resources Information Center

    Blum, Avram; Johnson, Eric J.

    2012-01-01

    This discussion draws attention to the discriminatory efforts of policymakers in Arizona to professionally marginalize public school teachers deemed to have an accent. In addition to debunking the linguistic and pedagogic validity of this policy, we emphasize the role of the media in the (re)construction and justification of language ideologies…

  18. A computer program for creating keyword indexes to textual data files

    USGS Publications Warehouse

    Moody, David W.

    1972-01-01

    A keyword-in-context (KWIC) or out-of-context (KWOC) index is a convenient means of organizing information. This keyword index program can be used to create either KWIC or KWOC indexes of bibliographic references or other types of information punched on. cards, typed on optical scanner sheets, or retrieved from various Department of Interior data bases using the Generalized Information Processing System (GIPSY). The index consists of a 'bibliographic' section and a keyword-section based on the permutation of. document titles, project titles, environmental impact statement titles, maps, etc. or lists of descriptors. The program can also create a back-of-the-book index to documents from a list of descriptors. By providing the user with a wide range of input and output options, the program provides the researcher, manager, or librarian with a means of-maintaining a list and index to documents in. a small library, reprint collection, or office file.

  19. Semantic Options in the Transitivity System: An Example of Textual Analysis.

    ERIC Educational Resources Information Center

    Lavid, Julia

    This article aims to discover the latent organization of a text by revealing a semantically motivated pattern of language functions that inform the theme of a story. it is shown how this pattern of linguistic features in the text provides insights into the literary effects of a description of a scene of a novel. The analysis proposed follows the…

  20. Semantic and Pragmatic Failure in Translating Literary Texts: Translators' Inconsistency and/or Textual Resistance

    ERIC Educational Resources Information Center

    AlBzoor, Baseel Ali

    2011-01-01

    Liyerature;Drawing upon intrinsic linguistic and cultural premises, the present study is an attempt to explore semantic and pragmatic failure, evidently and frequently arising while translating literary texts. This researcher has adopted a functional approach that hinges upon basic semantic and pragmatic premises that best fit the framework of an…

  1. Teaching children with autism to engage in conversational exchanges: script fading with embedded textual stimuli.

    PubMed Central

    Sarokoff, R A; Taylor, B A; Poulson, C L

    2001-01-01

    A multiple baseline across three sets of stimuli was used to assess the effects of a script-fading procedure using embedded text to teach 2 children with autism to engage in conversation statements about the stimuli. Both students stated all the scripted statements, and unscripted statements also increased. Generalization was assessed with novel peers and with untrained stimuli. PMID:11317993

  2. Textual Archaeology: Lessons in the History of Business Writing Pedagogy from a Medieval Oxford Scholar.

    ERIC Educational Resources Information Center

    Thomas, Martha Wetterhall

    2003-01-01

    Argues that Thomas Sampson, author of the 1396 "Modus Dictandi," deserves attention because of his work as a teacher. Explains that Sampson was a practitioner and instructor of the art of letter writing. Contends that Sampson's work is a discursive artifact yielding multiple insights into the origins of business communication as taught and…

  3. The School Leadership Literature in Managerialist Times: Exploring the Problem of Textual Apologism.

    ERIC Educational Resources Information Center

    Thrupp, Martin

    2003-01-01

    Critiques major topics or themes in school-leadership texts, such as problem-solving techniques; suggests alternative topics or themes for school administrators, such as ideas-based leadership. Draws implications for writers on school leadership. (Contains 59 references.) (PKP)

  4. Classification of images on the Internet by visual and textual information

    NASA Astrophysics Data System (ADS)

    Gevers, Theo; Aldershoff, Raango; Smeulders, Arnold W. M.

    1999-12-01

    In this paper, we study computational models and techniques to combine textural and image features for classification of images on Internet. A framework is given to index images on the basis of textural, pictorial and composite information. The scheme makes use of weighted document terms and color invariant image features to obtain a high-dimensional similarity descriptor to be used as an index. Based on supervised learning, the k-nearest neighbor classifier is used to organize images into semantically meaningful groups of Internet images. Internet images are first classified into photographical and synthetical images. After classifying images into photographical and synthetical images, we further classify photographical images into portraits and non-portraits. Further, synthetical images are classified into button and non-button images.

  5. Analysis of Textual Features of a New Reading Comprehension Assessment: MOCCA

    ERIC Educational Resources Information Center

    Seipel, Ben; Biancarosa, Gina; Carlson, Sarah; Davison, Mark

    2015-01-01

    Previous research has established two types of struggling readers: those who struggle with lower-level reading skills and those who struggle with higher-level reading skills (Cain & Oakhill, 2006; Perfetti, 2007). The latter group is commonly termed "poor comprehenders": readers who exhibit poor comprehension compared to peers with…

  6. Extraction of Temporal Networks from Term Co-Occurrences in Online Textual Sources

    PubMed Central

    Popović, Marko; Štefančić, Hrvoje; Sluban, Borut; Kralj Novak, Petra; Grčar, Miha; Mozetič, Igor; Puliga, Michelangelo; Zlatić, Vinko

    2014-01-01

    A stream of unstructured news can be a valuable source of hidden relations between different entities, such as financial institutions, countries, or persons. We present an approach to continuously collect online news, recognize relevant entities in them, and extract time-varying networks. The nodes of the network are the entities, and the links are their co-occurrences. We present a method to estimate the significance of co-occurrences, and a benchmark model against which their robustness is evaluated. The approach is applied to a large set of financial news, collected over a period of two years. The entities we consider are 50 countries which issue sovereign bonds, and which are insured by Credit Default Swaps (CDS) in turn. We compare the country co-occurrence networks to the CDS networks constructed from the correlations between the CDS. The results show relatively small, but significant overlap between the networks extracted from the news and those from the CDS correlations. PMID:25470498

  7. Infrastructure for dynamic knowledge integration--automated biomedical ontology extension using textual resources.

    PubMed

    Novácek, Vít; Laera, Loredana; Handschuh, Siegfried; Davis, Brian

    2008-10-01

    We present a novel ontology integration technique that explicitly takes the dynamics and data-intensiveness of e-health and biomedicine application domains into account. Changing and growing knowledge, possibly contained in unstructured natural language resources, is handled by application of cutting-edge Semantic Web technologies. In particular, semi-automatic integration of ontology learning results into a manually developed ontology is employed. This integration bases on automatic negotiation of agreed alignments, inconsistency resolution and natural language generation methods. Their novel combination alleviates the end-user effort in the incorporation of new knowledge to large extent. This allows for efficient application in many practical use cases, as we show in the paper. PMID:18694849

  8. An Analysis of Textual Cohesion in a Passage from Maria Gripe's "Hugo och Josefin."

    ERIC Educational Resources Information Center

    Andersson, Erik

    Sentence-by-sentence analysis of factual or propositional cohesion in the first 29 lines of a Swedish children's story finds several sources of coherence that contribute to its cohesion. First, the text receives much coherence from its description of a single event, a situation where happenings are normal and expected. Second, a rather primitive…

  9. Text-Based Recall and Extra-Textual Generations Resulting from Simplified and Authentic Texts

    ERIC Educational Resources Information Center

    Crossley, Scott A.; McNamara, Danielle S.

    2016-01-01

    This study uses a moving windows self-paced reading task to assess text comprehension of beginning and intermediate-level simplified texts and authentic texts by L2 learners engaged in a text-retelling task. Linear mixed effects (LME) models revealed statistically significant main effects for reading proficiency and text level on the number of…

  10. "Textual Power" and the Subject of Oral Interpretation: An Alternative Approach to Performing Literature.

    ERIC Educational Resources Information Center

    Bowman, Michael S.; Kistenberg, Cindy J.

    1992-01-01

    Proposes to supplement the changes in oral interpretation pedagogy brought about in broadening the idea of "text" by describing an alternative approach to analyzing and performing texts based on semiotic theory and Robert Scholes' model of reading. (SR)

  11. Language Legislation in the Belgian Colonial Charter of 1908: A Textual-Historical Analysis

    ERIC Educational Resources Information Center

    Meeuwis, Michael

    2015-01-01

    When in 1908 the Belgian government took over the Congo from King Leopold II, a charter was drafted that would serve as a constitution-like statutory code for the new colony. Article 3 in this "Colonial Charter" dealt with language and linguistic rights. It epitomized the duality of language questions with which Belgium remained faced…

  12. Problemes de L'Analyse Textuelle/Problems of Textual Analysis.

    ERIC Educational Resources Information Center

    Leon, Pierre R., Ed.; And Others

    This text compiles papers treating problems in literary analysis which were read at a conference at the University of Toronto, Canada. Papers include: (1) "Elements Phonostylistiques du Texte Litteraire," (2) Some uses of the Grammar in Poetic Analysis, (3) "Morphosyntaxe et Stylistique," (4) "Le Lexique dans l'Oeuvre Litteraire," (5) "Analyse…

  13. The Efficacy of Corrective Feedback and Textual Enhancement in Promoting the Acquisition of Grammatical Redundancies

    ERIC Educational Resources Information Center

    Lyddon, Paul A.

    2011-01-01

    Many second language acquisition researchers (e.g., Doughty & Williams, 1998; R. Ellis, 2007; Long, 1996, 2007; Lyster, Lightbown, & Spada, 1999; Russell & Spada, 2006) have advocated the use of negative feedback to promote learner noticing of errors and the internalization of correct forms. At the same time, the true efficacy of this practice is…

  14. Discovering Potential Precursors of Mammography Abnormalities based on Textual Features, Frequencies, and Sequences

    SciTech Connect

    Patton, Robert M; Potok, Thomas E

    2010-01-01

    Diagnosing breast cancer from mammography reports is heavily dependant on the time sequences of the patient visits. In the work described, we take a longitudinal view of the text of a patient s mam- mogram reports to explore the existence of certain phrase patterns that indicate future abnormalities may exist for the patient. Our approach uses various text analysis techniques combined with Haar wavelets for the discovery and analysis of such precursor phrase patterns. We believe the results show significant promise for the early detection of breast can- cer and other breast abnormalities.

  15. Employing Textual and Facial Emotion Recognition to Design an Affective Tutoring System

    ERIC Educational Resources Information Center

    Lin, Hao-Chiang Koong; Wang, Cheng-Hung; Chao, Ching-Ju; Chien, Ming-Kuan

    2012-01-01

    Emotional expression in Artificial Intelligence has gained lots of attention in recent years, people applied its affective computing not only in enhancing and realizing the interaction between computers and human, it also makes computer more humane. In this study, emotional expressions were applied into intelligent tutoring system, where learners'…

  16. Ambitions and Responsibilities: A Textual Analysis of the Norwegian National Curriculum Regulations for Nursing Education

    ERIC Educational Resources Information Center

    Solbrekke, Tone Dyrdal; Heggen, Kristin; Engebretsen, Eivind

    2014-01-01

    Society assigns professional educational programs the responsibility to aid students in learning and dedicate expert knowledge to furthering the well-being of citizens. This demand calls for addressing the how educational policies prioritize learning professionals' responsibility. Inspired by the theory of Jacques Derrida, we deconstruct the…

  17. A tectonically controlled basin-fill within the Valle del Cauca, West-Central Colombia

    SciTech Connect

    Rine, J.M.; Keith, J.F. Jr.; Alfonso, C.A.; Ballesteros, I.; Laverde, F.; Sacks, P.E.; Secor, D.T. Jr. ); Perez, V.E.; Bernal, I.; Cordoba, F.; Numpaque, L.E. )

    1993-02-01

    Tertiary strata of the Valle del Cauca reflect a forearc/foreland basin tectonic history spanning a period from pre-uplift of the Cordillera Central to initiation of uplift of the Cordillera Occidental. Stratigraphy of the Valle del Cauca begins with Jurassic-Cretaceous rocks of exotic and/or volcanic provenance and of oceanic origin. Unconformably overlying these are Eocene to Oligocene basal quartz-rich sandstones, shallow marine algal limestones, and fine-grained fluvial/deltaic mudstones and sandstones with coalbeds. These Eocene to Oligocene deposits represent a period of low tectonic activity. During late Oligocene to early Miocene, increased tectonic activity produced conglomeratic sediments which were transported from east to west, apparently derived from uplift of the Cordillera Central, and deposited within a fluvial to deltaic setting. East-west shortening of the Valle del Cauca basin folded the Eocene to early Miocene units, and additional uplift of the Cordillera Central during the later Miocene resulted in syn-tectonic deposition of alluvial fans. After additional fold and thrust deformation of the total Eocene-Miocene basin-fill, tectonic activity abated and Pliocene-Quaternary alluvial and lacustrine strata were deposited. Within the framework of this depositional and tectonic history of the Valle del Cauca, hydrocarbon exploration strategies can be formulated and evaluated.

  18. The c.657del5 variant in the NBN gene predisposes to pancreatic cancer.

    PubMed

    Borecka, Marianna; Zemankova, Petra; Lhota, Filip; Soukupova, Jana; Kleiblova, Petra; Vocka, Michal; Soucek, Pavel; Ticha, Ivana; Kleibl, Zdenek; Janatova, Marketa

    2016-08-10

    Pancreatic ductal adenocarcinoma (PDAC) is the sixth most frequent cancer type in the Czech Republic with a poor prognosis that could be improved by an early detection and subsequent surgical treatment combined with chemotherapy. Genetic factors play an important role in PDAC risk. We previously identified one PDAC patient harboring the Slavic founder deleterious mutation c.657del5 in the NBN gene, using a panel next-generation sequencing (NGS). A subsequent analysis of 241 unselected PDAC patients revealed other mutation carriers. The overall frequency of c.657del5 in unselected PDAC patients (5/241; 2.07%) significantly differed from that in non-cancer controls (2/915; 0.2%; P=0.006). The result indicates that the NBN c.657del5 variant represents a novel PDAC-susceptibility allele increasing PDAC risk (OR=9.7; 95% CI: 1.9 to 50.2). The increased risk of PDAC in follow-up recommendations for NBN mutation carriers should be considered if other studies also confirm an increased frequency of c.657del5 carriers in PDAC patients from other populations. PMID:27150568

  19. Calcio y la prevención del cáncer

    Cancer.gov

    Hoja informativa que resume los resultados de estudios sobre el calcio y la prevención del cáncer. Incluye información sobre las recomendaciones dietéticas para calcio y la cantidad de calcio en los alimentos y en complementos de calcio.

  20. 33 CFR 162.35 - Channel of Christina River, Del.; navigation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Channel of Christina River, Del.; navigation. 162.35 Section 162.35 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY INLAND WATERWAYS NAVIGATION REGULATIONS § 162.35 Channel...

  1. 33 CFR 162.35 - Channel of Christina River, Del.; navigation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Channel of Christina River, Del.; navigation. 162.35 Section 162.35 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY INLAND WATERWAYS NAVIGATION REGULATIONS § 162.35 Channel...

  2. 33 CFR 162.35 - Channel of Christina River, Del.; navigation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Channel of Christina River, Del.; navigation. 162.35 Section 162.35 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY INLAND WATERWAYS NAVIGATION REGULATIONS § 162.35 Channel...

  3. 33 CFR 162.35 - Channel of Christina River, Del.; navigation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Channel of Christina River, Del.; navigation. 162.35 Section 162.35 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY INLAND WATERWAYS NAVIGATION REGULATIONS § 162.35 Channel...

  4. 33 CFR 162.35 - Channel of Christina River, Del.; navigation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Channel of Christina River, Del.; navigation. 162.35 Section 162.35 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY INLAND WATERWAYS NAVIGATION REGULATIONS § 162.35 Channel...

  5. Community Arts Programs: Cohesion and Difference Case Studies. Henry Street Settlement and El Museo del Barrio

    ERIC Educational Resources Information Center

    Kiebert-Gruen, Cathleen

    2009-01-01

    A comparative case study of two cultural institutions, Henry Street Settlement and El Museo del Barrio, founded almost eighty years apart, were involved in social justice causes and community arts. Although both of these institutions participated in the political activism of their time, they also demonstrated an important adaptability. They were…

  6. ATMOSPHERIC VOLATILE ORGANIC COMPOUND MEASUREMENTS DURING THE 1996 PASO DEL NORTE OZONE STUDY

    EPA Science Inventory

    Ambient air VOC samples were collected at surface air quality monitoring sites, near sources of interest, and aloft on the US (El Paso) and Mexican (Ciudad Juarez) side of the border during a six-week period of the 1996 Paso del Norte Ozone Study. Samples were collected at five...

  7. Dropouts, Stopouts, Optouts at Del Mar College: Spring 1991. Report of a Joint Research Project.

    ERIC Educational Resources Information Center

    Luckie, Jo Ann I.; Bonham, L. Adrianne

    A research project investigated 2,313 persons who attended Del Mar College (Texas) during fall 1990 but did not enroll for spring 1991. Four sets of data were collected: (1) limited demographic information on the total student body; (2) demographic information drawn from school records to describe all nonreturnees; (3) demographic information…

  8. Dolores Del Rio, the First "Latin Invasion", and Hollywood's Transition to Sound

    ERIC Educational Resources Information Center

    Beltran, Mary

    2005-01-01

    The career and promotion of Mexican actress Dolores Del Rio as a case study of how Hollywood's shift to sound film affected Latino and Latina actors is examined. It reveals the way in which the starring opportunities for Latinos dwindled when accent and language increasingly marked them as nonwhite in the 1930s in the talkie films.

  9. Tratamiento del cáncer sin daño al corazón

    Cancer.gov

    Investigadores de los campos de oncología y de cardiología están trabajando para encontrar formas de impedir, manejar y posiblemente aun revertir los efectos secundarios cardiovasculares de ciertas terapias del cáncer.

  10. Exploración del Nuevo Laboratorio Científico de Marte

    NASA Video Gallery

    Únase a Fernando Abilleira, un analista de trayectoria de la NASA para la Oficina de Exploración de Marte, y conozca las nuevas tecnologías que el nuevo robot Curiosity del Laboratorio Científico d...

  11. Advances in optical technologies at Pontificia Universidad Católica del Perú

    NASA Astrophysics Data System (ADS)

    Baldwin, Guillermo; Asmad, Miguel; Romero, Sandra; Gonzales, Franco; Gálvez, Gonzalo; Sánchez, Rubén; Córdova, Darwin

    2011-05-01

    In this work, it is shown a panoramically view of advances and works on fundamental optical technology developed and Physics Section at Pontificia Universidad Católica del Perú PUCP in Lima Peru. This includes works in, precision optics manufacturing, optical testing, and optical design and simulation and also in optical thin film evaporation and its design techniques

  12. Urban Impact of Dissolved Metals in the Paso del Norte Segment of the Rio Grande

    ERIC Educational Resources Information Center

    Freiwan, Sumayeh Ahmad

    2013-01-01

    The Paso del Norte segment of the Rio Grande experiences two seasons per year; the (wet) irrigation season and the (dry) non-irrigation season. The goal of this study was to improve the understanding of occurrence and contribution of dissolved metals in this region during the non-irrigation season. The objectives of this study were to (1) evaluate…

  13. A Failed Utopia in Marcela Del Río's "Proceso a Faubritten"

    ERIC Educational Resources Information Center

    Manickam, Samuel

    2014-01-01

    In Marcela del Río's science fiction novel "Proceso a Faubritten," utopia comes in the form of eternal life for all of humanity, thanks to Dr. Alexander Faubritten's "Bomba L." This polyphonic work includes diaries by Faubritten and his Mexican lover, María Corona. In my analysis of these two diaries, I will show how…

  14. Se lanza Red Nacional de Estudios Clínicos del NCI

    Cancer.gov

    El Instituto Nacional del Cáncer (NCI) puso en marcha una nueva red de investigación de estudios clínicos con el objetivo de mejorar el tratamiento de más de 1,6 millones de estadounidenses que reciben un diagnóstico de cáncer cada año.

  15. Control del dolor: Apoyo para las personas con cáncer

    Cancer.gov

    Contiene información sobre las medicinas contra el dolor para pacientes con cáncer, los planes para controlarlo, cómo hablar con su equipo de atención médica sobre el dolor que usted siente y qué hacer para controlar los efectos físicos y emocionales del

  16. Interstitial deletion of the long arm of chromosome 2: del(2)(q31q33).

    PubMed

    Al-Awadi, S A; Farag, T I; Naguib, K; Teebi, A; Cuschieri, A; Al-Othman, S; Sundareshan, T S

    1983-12-01

    A child with a de novo interstitial deletion, 46,XX,del(2)(q31q33), is described. Clinical features included psychomotor retardation, hypotonia, microcephaly, hypertelorism, downward slanting palpebral fissures, macrostomia, cleft palate, micrognathia, abnormal ears, overlapping fingers, simian creases, and rocker bottom feet. PMID:6655673

  17. Exploración del Sistema Solar -- Una mirada hacia el futuro

    NASA Video Gallery

    ¿Piensas que ya sabemos todo acerca de nuestro sistema solar? La realidad es que apenas hemos comenzado con lo que hay para conocer. Únete a la NASA, en el envío de misiones a los confines del sist...

  18. Use of del Nido Cardioplegia for Adult Cardiac Surgery at the Cleveland Clinic: Perfusion Implications

    PubMed Central

    Kim, Kuna; Ball, Clifford; Grady, Patrick; Mick, Stephanie

    2014-01-01

    Abstract: Cardiac arrest by cardioplegia provides a reproducible and safe method to induce and maintain electromechanical cardiac quiescence. Techniques of intraoperative myocardial protection are constantly evolving. For the past three decades, modified Buckberg cardioplegia solution has been used for adult cardiac surgery at the Cleveland Clinic. This formulation serves as the crystalloid component, which is delivered 4:1 with oxygenated patient’s blood to crystalloid. Meanwhile, our use of the del Nido cardioplegia solution in adult patients, heretofore primarily used in pediatric cardiac surgical centers, has been increasing over the past several years. Single-dose, cold blood del Nido cardioplegia can be delivered antegrade if the duration of the operation will be limited and if there is no significant coronary artery disease or aortic insufficiency that would limit the distribution of cardioplegia. The addition of del Nido cardioplegia to our cardioplegia armamentarium allows us to customize our myocardial protection strategies for different surgical needs. This article aims to provide information on technical aspects of del Nido cardioplegia in adult cardiac surgery and its use at the Cleveland Clinic in the adult surgical population. PMID:26357803

  19. Fermions tunnelling from 5D general rotating charged Gödel black hole

    NASA Astrophysics Data System (ADS)

    Song, Shi-Xiong; Huang, Jiang; Ren, Ji-Rong

    2011-01-01

    Using the tunneling method we derive the Hawking temperature of the nonextremal rotating charged black hole in the Gödel universe of five-dimensional minimal supergravity theory found by Wu. We successfully recovered the tunneling probability of charged Dirac particles and the expected Hawking temperature of the black hole, which is exactly consistent with that obtained by other methods.

  20. Functional Rescue of F508del-CFTR Using Small Molecule Correctors

    PubMed Central

    Molinski, Steven; Eckford, Paul D. W.; Pasyk, Stan; Ahmadi, Saumel; Chin, Stephanie; Bear, Christine E.

    2012-01-01

    High-throughput screens for small molecules that are effective in “correcting” the functional expression of F508del-CFTR have yielded several promising hits. Two such compounds are currently in clinical trial. Despite this success, it is clear that further advances will be required in order to restore 50% or greater of wild-type CFTR function to the airways of patients harboring the F508del-CFTR protein. Progress will be enhanced by our better understanding of the molecular and cellular defects caused by the F508del mutation, present in 90% of CF patients. The goal of this chapter is to review the current understanding of defects caused by F508del in the CFTR protein and in CFTR-mediated interactions important for its biosynthesis, trafficking, channel function, and stability at the cell surface. Finally, we will discuss the gaps in our knowledge regarding the mechanism of action of existing correctors, the unmet need to discover compounds which restore proper CFTR structure and function in CF affected tissues and new strategies for therapy development. PMID:23055971