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Sample records for tipos textuales del

  1. Textual Design and Student Learning.

    ERIC Educational Resources Information Center

    Parer, Michael S.

    A study was conducted to examine the relationships of four areas of textual design factors that are relevant to external students' learning as they use their course study guides: the micro and macro textual features, the linguistics, and the instructional design elements. Twelve external students from two units at the Gippsland Institute were…

  2. An Approach to Textual Steganography

    NASA Astrophysics Data System (ADS)

    Morran, Michael; Weir, George R. S.

    Textual steganography is a means of concealing an encoded message within text. The appeal in such a system is its potential for hiding the fact that encoding is taking place. The failure to hide the presence of encoding is a form of information leakage and an inherent risk since it suggests that there is important or valuable information in transit. This is considered a major limitation of existing cryptographic techniques as applied to secure information transfer. In this paper, we describe an experimental system that we have developed as a test bed for textual steganography. This system allows us to explore the application of part of speech tagging, word sense disambiguation and synonym replacement as component strategies for textual steganography.

  3. La busqueda textual por computadora (Textual Search by Computer)

    ERIC Educational Resources Information Center

    Davison, Ned J.

    1977-01-01

    Describes the use of the computer program EDIT for textual searches to locate a certain programmed word or word root. In the examples explained here, the vocabulary search is performed on poetry and allows examination of the metaphorical and conceptual poetic atmosphere achieved through word use. (Text is in Spanish.) (CHK)

  4. A Multimodal Perspective on Textuality and Contexts

    ERIC Educational Resources Information Center

    Jewitt, Carey

    2007-01-01

    Textuality is often thought of in linguistic terms; for instance, the talk and writing that circulate in the classroom. In this paper I take a multimodal perspective on textuality and context. I draw on illustrative examples from school Science and English to examine how image, colour, gesture, gaze, posture and movement--as well as writing and…

  5. Sexuality, Textuality: The Cultural Work of Plagiarism.

    ERIC Educational Resources Information Center

    Howard, Rebecca Moore

    2000-01-01

    Considers how plagiarism continues to elude definition because teachers cannot possibly formulate and act on a definition of plagiarism that articulates both its textual and sexual work. Discusses linking sexual property to textual transgression and rejecting metaphors in relationship to rejecting plagiarism. Suggests educators stop using the term

  6. [Herbalogical textual research of Wuyi].

    PubMed

    Zhao, Hai-liang; Zhang, Rui-xian

    2015-11-01

    Wuyi is one of the Chinese medicine recorded in Shennong's Herbal Classic and many other herbal books during the long history period. Up to now, Wuyi is still an important medicine used for insecticidal and removing food retention. Recent researches indicated that Wuyi also had the function of anti-malaria and treating herpetic simplex keratitis. Therefore, Wuyi had notable value on clinic and development of new medicine. The herbalogical textual research on Wuyi was conducted through investigation of the literature of materia medica during the long historical period from Han Dynasty. It was demonstrated by this work that the original plants of Wuyi include Ulmus macrocarpa Hance and Hemiptelea davidii (Hance) Planch, in which, U. macrocarpa was the quality specie. U. pumila was the false specie which cause confusing. The medicine Wuyi was the processed product made from the nutlet of the plants through fermentation with other additive agents. PMID:27097433

  7. Textual Analysis in Mass Communication Studies: Theory and Methodology.

    ERIC Educational Resources Information Center

    Curtin, Patricia A.

    This study examines textual analysis methodology as applied to mass communication studies. It focuses particularly on the theoretical basis of textual analysis, the analytical process, and congruent theoretical perspectives. Although the term "textual analysis" is often used generically, this study differentiates textual analysis as developed by…

  8. Universal lossless compression algorithm for textual images

    NASA Astrophysics Data System (ADS)

    al Zahir, Saif

    2012-03-01

    In recent years, an unparalleled volume of textual information has been transported over the Internet via email, chatting, blogging, tweeting, digital libraries, and information retrieval systems. As the volume of text data has now exceeded 40% of the total volume of traffic on the Internet, compressing textual data becomes imperative. Many sophisticated algorithms were introduced and employed for this purpose including Huffman encoding, arithmetic encoding, the Ziv-Lempel family, Dynamic Markov Compression, and Burrow-Wheeler Transform. My research presents novel universal algorithm for compressing textual images. The algorithm comprises two parts: 1. a universal fixed-to-variable codebook; and 2. our row and column elimination coding scheme. Simulation results on a large number of Arabic, Persian, and Hebrew textual images show that this algorithm has a compression ratio of nearly 87%, which exceeds published results including JBIG2.

  9. Textual Enhancement of Input: Issues and Possibilities

    ERIC Educational Resources Information Center

    Han, ZhaoHong; Park, Eun Sung; Combs, Charles

    2008-01-01

    The input enhancement hypothesis proposed by Sharwood Smith (1991, 1993) has stimulated considerable research over the last 15 years. This article reviews the research on textual enhancement of input (TE), an area where the majority of input enhancement studies have aggregated. Methodological idiosyncrasies are the norm of this body of research.…

  10. Exploring Grade 1 Students' Textual Connections

    ERIC Educational Resources Information Center

    Pantaleo, Sylvia

    2004-01-01

    This article focuses specifically on an aspect of Grade 1 children's literary understanding--the textual associations made by the students as they discussed nine picture books. This work extends the small body of research that has examined the responses of Grade 1 children (e.g., Kiefer, 1993; McGee, 1992; Sipe, 2000a), and also contributes to

  11. Exploring Grade 1 Students' Textual Connections

    ERIC Educational Resources Information Center

    Pantaleo, Sylvia

    2004-01-01

    This article focuses specifically on an aspect of Grade 1 children's literary understanding--the textual associations made by the students as they discussed nine picture books. This work extends the small body of research that has examined the responses of Grade 1 children (e.g., Kiefer, 1993; McGee, 1992; Sipe, 2000a), and also contributes to…

  12. Natural language insensitive short textual string compression

    NASA Astrophysics Data System (ADS)

    Constantinescu, Cornel; Trelewicz, Jennifer Q.; Arps, Ronald B.

    2004-01-01

    There are applications (such as Internet search engines) where short textual strings, for example abstracts or pieces of Web pages, need to be compressed independently of each other. The usual adaptive compression algorithms perform poorly on these short strings due to the lack of necessary data to learn. In this manuscript, we introduce a compression algorithm targeting short text strings; e.g., containing a few hundred symbols. We also target natural language insensitivity, to facilitate its robust compression and fast implementation. The algorithm is based on the following findings. Applying the move-to-front transform (MTFT) after the Burrows-Wheeler transform (BWT) brings the short textual strings to a "normalized form" where the distribution of the resulting "ranks" has a shape similar over the set of natural language strings. This facilitates the use of a static coding method with few variations, which we call shortBWT, where no on-line learning is needed, to encode the ranks. Finally, for short strings, shortBWT runs very fast because the strings fit into the cache of most current computers. The introduction for this paper will review the mathematical bases of BWT and MTF, it will also review our recently published metric for rapidly pre-characterizing the compressibility of such short textual strings when using these transforms.

  13. Scalable Visual Analytics of Massive Textual Datasets

    SciTech Connect

    Krishnan, Manoj Kumar; Bohn, Shawn J.; Cowley, Wendy E.; Crow, Vernon L.; Nieplocha, Jarek

    2007-04-01

    This paper describes the first scalable implementation of text processing engine used in Visual Analytics tools. These tools aid information analysts in interacting with and understanding large textual information content through visual interfaces. By developing parallel implementation of the text processing engine, we enabled visual analytics tools to exploit cluster architectures and handle massive dataset. The paper describes key elements of our parallelization approach and demonstrates virtually linear scaling when processing multi-gigabyte data sets such as Pubmed. This approach enables interactive analysis of large datasets beyond capabilities of existing state-of-the art visual analytics tools.

  14. Does textual feedback hinder spoken interaction in natural language?

    PubMed

    Le Bigot, Ludovic; Terrier, Patrice; Jamet, Eric; Botherel, Valerie; Rouet, Jean-Francois

    2010-01-01

    The aim of the study was to determine the influence of textual feedback on the content and outcome of spoken interaction with a natural language dialogue system. More specifically, the assumption that textual feedback could disrupt spoken interaction was tested in a human-computer dialogue situation. In total, 48 adult participants, familiar with the system, had to find restaurants based on simple or difficult scenarios using a real natural language service system in a speech-only (phone), speech plus textual dialogue history (multimodal) or text-only (web) modality. The linguistic contents of the dialogues differed as a function of modality, but were similar whether the textual feedback was included in the spoken condition or not. These results add to burgeoning research efforts on multimodal feedback, in suggesting that textual feedback may have little or no detrimental effect on information searching with a real system. STATEMENT OF RELEVANCE: The results suggest that adding textual feedback to interfaces for human-computer dialogue could enhance spoken interaction rather than create interference. The literature currently suggests that adding textual feedback to tasks that depend on the visual sense benefits human-computer interaction. The addition of textual output when the spoken modality is heavily taxed by the task was investigated. PMID:20069480

  15. Essjay's "Ethos": Rethinking Textual Origins and Intellectual Property

    ERIC Educational Resources Information Center

    Brown, James J., Jr.

    2009-01-01

    Discussions of intellectual property are often the focus of rhetoric and composition research, and the question of textual origins grounds these discussions. Through an examination of Wikipedia, the online encyclopedia anyone can edit, this essay addresses disciplinary concerns about textual origins and intellectual property through a discussion

  16. Permeable Textual Discussion in Tracked Language Arts Classrooms

    ERIC Educational Resources Information Center

    Gritter, Kristine

    2012-01-01

    Permeable textual discussion occurs when the unofficial texts and discursive practices and personal histories that are already recognized and valued in students' cultures are scaffolds to academically sanctioned literacies. Ideally, permeable textual discussions are safe havens where students' identities (racial, gender, world views) are…

  17. Essjay's "Ethos": Rethinking Textual Origins and Intellectual Property

    ERIC Educational Resources Information Center

    Brown, James J., Jr.

    2009-01-01

    Discussions of intellectual property are often the focus of rhetoric and composition research, and the question of textual origins grounds these discussions. Through an examination of Wikipedia, the online encyclopedia anyone can edit, this essay addresses disciplinary concerns about textual origins and intellectual property through a discussion…

  18. Causal discovery from medical textual data.

    PubMed Central

    Mani, S.; Cooper, G. F.

    2000-01-01

    Medical records usually incorporate investigative reports, historical notes, patient encounters or discharge summaries as textual data. This study focused on learning causal relationships from intensive care unit (ICU) discharge summaries of 1611 patients. Identification of the causal factors of clinical conditions and outcomes can help us formulate better management, prevention and control strategies for the improvement of health care. For causal discovery we applied the Local Causal Discovery (LCD) algorithm, which uses the framework of causal Bayesian Networks to represent causal relationships among model variables. LCD takes as input a dataset and outputs causes of the form variable Y causally influences variable Z. Using the words that occur in the discharge summaries as attributes for input, LCD output 8 purported causal relationships. The relationships ranked as most probable subjectively appear to be most causally plausible. PMID:11079942

  19. [Achievement of Qimin Yaoshu in area of herbalogical textual research].

    PubMed

    Zhao, Hai-Liang; Zhang, Rui-Xian

    2015-11-01

    The achievement of Qimin Yaoshu in the area of herbalogical textual research was illustrated in this paper. Qimin Yaoshu quoted and keeped many contents from ancient agriculture books related in herbalogical literature. It also recorded the information of lots of tropical and subtropical plants. The author bringed forwarded many experiences indistinguishing plants and clarified some long last confused or wrong opinions. The studying philosophy and methods of the authors gave us much enlightenment in our herbalogical textual research. It should be taken into account when the herbalogical textual research was carried out. PMID:27071275

  20. A Computational Approach to Qualitative Analysis in Large Textual Datasets

    PubMed Central

    Evans, Michael S.

    2014-01-01

    In this paper I introduce computational techniques to extend qualitative analysis into the study of large textual datasets. I demonstrate these techniques by using probabilistic topic modeling to analyze a broad sample of 14,952 documents published in major American newspapers from 1980 through 2012. I show how computational data mining techniques can identify and evaluate the significance of qualitatively distinct subjects of discussion across a wide range of public discourse. I also show how examining large textual datasets with computational methods can overcome methodological limitations of conventional qualitative methods, such as how to measure the impact of particular cases on broader discourse, how to validate substantive inferences from small samples of textual data, and how to determine if identified cases are part of a consistent temporal pattern. PMID:24498398

  1. A computational approach to qualitative analysis in large textual datasets.

    PubMed

    Evans, Michael S

    2014-01-01

    In this paper I introduce computational techniques to extend qualitative analysis into the study of large textual datasets. I demonstrate these techniques by using probabilistic topic modeling to analyze a broad sample of 14,952 documents published in major American newspapers from 1980 through 2012. I show how computational data mining techniques can identify and evaluate the significance of qualitatively distinct subjects of discussion across a wide range of public discourse. I also show how examining large textual datasets with computational methods can overcome methodological limitations of conventional qualitative methods, such as how to measure the impact of particular cases on broader discourse, how to validate substantive inferences from small samples of textual data, and how to determine if identified cases are part of a consistent temporal pattern. PMID:24498398

  2. The visual analysis of textual information: Browsing large document sets

    SciTech Connect

    Thomas, J.; Pennock, K.; Fiegel, T.; Wise, J.; Pottier, M.; Schur, A.; Crow, V.; Lantrip, D.

    1995-05-01

    Visualization tools have been invaluable in the process of scientific discovery by providing researchers with insights gained through graphical tools and techniques. At PNL, the Multidimensional Visualization and Advanced Browsing (MVAB) project is extending visualization technology to the problems of intelligence analysis of textual documents by creating spatial representations of textual information. By representing an entire corpus of documents as points in a coordinate space of two or more dimensions, the tools developed by the MVAB team give the analyst the ability to quickly browse the entire document base and determine relationships among documents and publication patterns not readily discernible through traditional lexical means.

  3. Shaping Up? Three Acts of Education Studies as Textual Critique

    ERIC Educational Resources Information Center

    McDougall, Julian; Walker, Stephen; Kendall, Alex

    2006-01-01

    This paper presents a study of dominant educational discourses through textual critique and argues that such an approach enables education studies to preserve an important distinction from teacher training. The texts deconstructed here are specific to English education, but the discourses at work have international relevance as the rhetorics of…

  4. Textual Analyses of Nutrition Messages on Prime Time Television.

    ERIC Educational Resources Information Center

    Wadsworth, Laurie A.; Berenbaum, Shawna

    2001-01-01

    Using textual analysis of 805 incidents in 10 television programs and surrounding commercials, foods portrayed were compared with nutrition guidelines. Foods tended to be higher in fat and lower in fiber, and food portrayals had social and psychological meanings. Adverse health effects of foods low in nutrients were not depicted. (Contains 57

  5. A comprehensive program for textual concordances and statistics

    NASA Technical Reports Server (NTRS)

    Ule, L. A.

    1973-01-01

    Literary research tool can provide concordance and many other textual statistics relating to authorship or sequence of composition. Mechanical text manipulation provides wide variety of text formats and conventions (such as upper case). This program is written in FORTRAN H for use on IBM-360 computer.

  6. Voice Construction, Assessment, and Extra-Textual Identity

    ERIC Educational Resources Information Center

    Tardy, Christine M.

    2012-01-01

    The concept of voice has long attracted the attention of teachers, but more recently has also been the focus of a growing body of research aiming to understand voice as self-representation in writing. Adopting a socio-cultural orientation to voice, studies have revealed much about how textual choices are used by readers to build images of…

  7. Marking Importance in Lectures: Interactive and Textual Orientation

    ERIC Educational Resources Information Center

    Deroey, Katrien L. B.

    2015-01-01

    This paper provides a comprehensive overview of lexicogrammatical markers of important lecture points and proposes a classification in terms of their interactive and textual orientation. The importance markers were extracted from the British Academic Spoken English corpus using corpus-driven and corpus-based methods. The classification is based on…

  8. Marking Importance in Lectures: Interactive and Textual Orientation

    ERIC Educational Resources Information Center

    Deroey, Katrien L. B.

    2015-01-01

    This paper provides a comprehensive overview of lexicogrammatical markers of important lecture points and proposes a classification in terms of their interactive and textual orientation. The importance markers were extracted from the British Academic Spoken English corpus using corpus-driven and corpus-based methods. The classification is based on

  9. Textual Analyses of Nutrition Messages on Prime Time Television.

    ERIC Educational Resources Information Center

    Wadsworth, Laurie A.; Berenbaum, Shawna

    2001-01-01

    Using textual analysis of 805 incidents in 10 television programs and surrounding commercials, foods portrayed were compared with nutrition guidelines. Foods tended to be higher in fat and lower in fiber, and food portrayals had social and psychological meanings. Adverse health effects of foods low in nutrients were not depicted. (Contains 57…

  10. Textual appropriation in engineering master's theses: a preliminary study.

    PubMed

    Eckel, Edward J

    2011-09-01

    In the thesis literature review, an engineering graduate student is expected to place original research in the context of previous work by other researchers. However, for some students, particularly those for whom English is a second language, the literature review may be a mixture of original writing and verbatim source text appropriated without quotations. Such problematic use of source material leaves students vulnerable to an accusation of plagiarism, which carries severe consequences. Is such textual appropriation common in engineering master's writing? Furthermore, what, if anything, can be concluded when two texts have been found to have textual material in common? Do existing definitions of plagiarism provide a sufficient framework for determining if an instance of copying is transgressive or not? In a preliminary attempt to answer these questions, text strings from a random sample of 100 engineering master's theses from the ProQuest Dissertations and Theses database were searched for appropriated verbatim source text using the Google search engine. The results suggest that textual borrowing may indeed be a common feature of the master's engineering literature review, raising questions about the ability of graduate students to synthesize the literature. The study also illustrates the difficulties of making a determination of plagiarism based on simple textual similarity. A context-specific approach is recommended when dealing with any instance of apparent copying. PMID:20521174

  11. Computer-Assisted Search Of Large Textual Data Bases

    NASA Technical Reports Server (NTRS)

    Driscoll, James R.

    1995-01-01

    "QA" denotes high-speed computer system for searching diverse collections of documents including (but not limited to) technical reference manuals, legal documents, medical documents, news releases, and patents. Incorporates previously available and emerging information-retrieval technology to help user intelligently and rapidly locate information found in large textual data bases. Technology includes provision for inquiries in natural language; statistical ranking of retrieved information; artificial-intelligence implementation of semantics, in which "surface level" knowledge found in text used to improve ranking of retrieved information; and relevance feedback, in which user's judgements of relevance of some retrieved documents used automatically to modify search for further information.

  12. Methodology to Build Medical Ontology from Textual Resources

    PubMed Central

    Baneyx, Audrey; Charlet, Jean; Jaulent, Marie-Christine

    2006-01-01

    In the medical field, it is now established that the maintenance of unambiguous thesauri goes through ontologies. Our research task is to help pneumologists code acts and diagnoses with a software that represents medical knowledge through a domain ontology. In this paper, we describe our general methodology aimed at knowledge engineers in order to build various types of medical ontologies based on terminology extraction from texts. The hypothesis is to apply natural language processing tools to textual patient discharge summaries to develop the resources needed to build an ontology in pneumology. Results indicate that the joint use of distributional analysis and lexico-syntactic patterns performed satisfactorily for building such ontologies. PMID:17238295

  13. Textual standardization and the DSM-5 "common language".

    PubMed

    Kelly, Patty A

    2014-06-01

    In February 2010, the American Psychiatric Association (APA) launched their DSM-5 website with details about the development of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). The APA invited "the general public" to review the draft diagnostic criteria and provide written comments and suggestions. This revision marks the first time the APA has solicited public review of their diagnostic manual. This article analyzes reported speech on the DSM-5 draft diagnostic criteria for the classification Posttraumatic Stress Disorder. It demonstrates how textual standardization facilitates the cultural portability of the DSM-5 diagnostic criteria such that a community of speakers beyond the borders of the APA come to be seen as exemplary speakers, writers, and revisers of the professional style. Furthermore, analysis shows how co-authoring practices recontextualize the "voice" and persona of putative patient reported speech on Criterion D2. As a consequence of textual standardization, spoken discourse becomes recontextualized as the product of scientific inquiry and the organization of psychiatric knowledge. PMID:24682628

  14. Textual, Genre and Social Features of Spoken Grammar: A Corpus-Based Approach

    ERIC Educational Resources Information Center

    Perez-Llantada, Carmen

    2009-01-01

    This paper describes a corpus-based approach to teaching and learning spoken grammar for English for Academic Purposes with reference to Bhatia's (2002) multi-perspective model for discourse analysis: a textual perspective, a genre perspective and a social perspective. From a textual perspective, corpus-informed instruction helps students identify

  15. The Target of the Question: A Taxonomy of Textual Features for Cambridge University "O" Levels English

    ERIC Educational Resources Information Center

    Benjamin, Shanti Isabelle

    2015-01-01

    This study investigates the typical textual features that are most frequently targeted in short-answer reading comprehension questions of the Cambridge University "O" Level English Paper 2. Test writers' awareness of how textual features impact on understanding of meanings in text decisions will determine to great extent their decisions

  16. Une Analyse automatique en syntaxe textuelle (An Automated Analysis of Textual Syntax). Publication K-5.

    ERIC Educational Resources Information Center

    Ladouceur, Jacques

    This study reports the use of automated textual analysis on a French novel. An introductory section chronicles the history of artificial intelligence, focusing on its use with natural languages, and discusses its application to textual syntax. The first chapter examines computational linguistics in greater detail, looking at its relationship to…

  17. The Target of the Question: A Taxonomy of Textual Features for Cambridge University "O" Levels English

    ERIC Educational Resources Information Center

    Benjamin, Shanti Isabelle

    2015-01-01

    This study investigates the typical textual features that are most frequently targeted in short-answer reading comprehension questions of the Cambridge University "O" Level English Paper 2. Test writers' awareness of how textual features impact on understanding of meanings in text decisions will determine to great extent their decisions…

  18. The Use of Textual Memorisation in Foreign Language Learning: Hearing the Chinese Learner and Teacher Voice

    ERIC Educational Resources Information Center

    Yu, Xia

    2014-01-01

    Textual memorisation is a widely used yet underexplored language practice in foreign language teaching and learning in China. The research addresses the need for a comprehensive and in-depth understanding of the practices and beliefs of Chinese learners regarding the use of textual memorisation in foreign language learning. This article reports on…

  19. Textual, Genre and Social Features of Spoken Grammar: A Corpus-Based Approach

    ERIC Educational Resources Information Center

    Perez-Llantada, Carmen

    2009-01-01

    This paper describes a corpus-based approach to teaching and learning spoken grammar for English for Academic Purposes with reference to Bhatia's (2002) multi-perspective model for discourse analysis: a textual perspective, a genre perspective and a social perspective. From a textual perspective, corpus-informed instruction helps students identify…

  20. The Use of Textual Memorisation in Foreign Language Learning: Hearing the Chinese Learner and Teacher Voice

    ERIC Educational Resources Information Center

    Yu, Xia

    2014-01-01

    Textual memorisation is a widely used yet underexplored language practice in foreign language teaching and learning in China. The research addresses the need for a comprehensive and in-depth understanding of the practices and beliefs of Chinese learners regarding the use of textual memorisation in foreign language learning. This article reports on

  1. Textual Input Enhancement for Vowel Blindness: A Study with Arabic ESL Learners

    ERIC Educational Resources Information Center

    Alsadoon, Reem; Heift, Trude

    2015-01-01

    This study explores the impact of textual input enhancement on the noticing and intake of English vowels by Arabic L2 learners of English. Arabic L1 speakers are known to experience "vowel blindness," commonly defined as a difficulty in the textual decoding and encoding of English vowels due to an insufficient decoding of the word form.

  2. The Effect of Different Textual Narrations on Students' Explanations at the Submicroscopic Level in Chemistry

    ERIC Educational Resources Information Center

    Al-Balushi, Sulaiman M.

    2013-01-01

    The effect of different textual versions (macroscopic (control), submicroscopic, and guided imagery) of the explanation of a chemical phenomenon on students' submicroscopic explanation of a related phenomenon was examined. The sample included 152 pre-service science teachers. The three textual versions of the explanation were distributed randomly…

  3. Textual Input Enhancement for Vowel Blindness: A Study with Arabic ESL Learners

    ERIC Educational Resources Information Center

    Alsadoon, Reem; Heift, Trude

    2015-01-01

    This study explores the impact of textual input enhancement on the noticing and intake of English vowels by Arabic L2 learners of English. Arabic L1 speakers are known to experience "vowel blindness," commonly defined as a difficulty in the textual decoding and encoding of English vowels due to an insufficient decoding of the word form.…

  4. The Effects of Textual Enhancement Type on L2 Form Recognition and Reading Comprehension in Spanish

    ERIC Educational Resources Information Center

    LaBrozzi, Ryan M.

    2016-01-01

    Previous research investigating the effectiveness of textual enhancement as a tool to draw adult second language (L2) learners' attention to the targeted linguistic form has consistently produced mixed results. This article examines how L2 form recognition and reading comprehension are affected by different types of textual enhancement.…

  5. Analysis of Financial Markets' Fluctuation by Textual Information

    NASA Astrophysics Data System (ADS)

    Izumi, Kiyoshi; Goto, Takashi; Matsui, Tohgoroh

    In this study, we proposed a new text-mining methods for long-term market analysis. Using our method, we analyzed monthly price data of financial markets; Japanese government bond market, Japanese stock market, and the yen-dollar market. First we extracted feature vectors from monthly reports of Bank of Japan. Then, trends of each market were estimated by regression analysis using the feature vectors. As a result, determination coefficients were over 75%, and market trends were explained well by the information that was extracted from textual data. We compared the predictive power of our method among the markets. As a result, the method could estimate JGB market best and the stock market is the second.

  6. Self-plagiarism and textual recycling: legitimate forms of research misconduct.

    PubMed

    Bruton, Samuel V

    2014-01-01

    The concept of self-plagiarism frequently elicits skepticism and generates confusion in the research ethics literature, and the ethical status of what is often called "textual recycling" is particularly controversial. I argue that, in general, self-plagiarism is unethical because it is deceptive and dishonest. I then distinguish several forms of it and argue against various common rationalizations for textual recycling. I conclude with a discussion of two instances of textual recycling, distinguishing them in terms of their ethical seriousness but concluding that both are ethically problematic. PMID:24325212

  7. The Army as Textual Community: Exploring Mismatches in the Concepts of Attribution, Appropriation, and Shared Goals

    ERIC Educational Resources Information Center

    Anson, Chris; Neely, Shawn

    2010-01-01

    This webtext examines the practices of authorial attribution in textual production in higher education (where notions of individual authorship and intellectual property prevail, particularly at military academies) and in the military (which has a more public conception of authorship).

  8. The Text's the Thing: Using (Neglected) Issues of Textual Scholarship to Help Students Reimagine Shakespeare

    ERIC Educational Resources Information Center

    Parsons, Scott

    2009-01-01

    Do individuals know what words Shakespeare actually wrote? Exploring these issues can yield dramatic interest. With references to Shakespeare's Quartos and Folios, the author examines key textual issues and discrepancies in classroom studies of "Hamlet." (Contains 8 notes.)

  9. [Textual research on the edition of WU Kun's books].

    PubMed

    Wang, Xu-Guang; Lu, Xiang

    2013-03-01

    WU Kun is a famous physician of the Xin'an School. He wrote a 6-volume Yi fang kao (Textual Research on Recipes) in 1584, a 24-volume Wu zhu su wen (Wu's Annotation of Plain Questions) in 1594, a 6-volume Zhen fang liu ji (Six Collections of Acupuncture and Prescription) in 1618 block-printed and funded by CHENG Biao, and a 2-volume Mai yu (Language of Pulse) with writing date unknown. For Yi fang kao, there were 4 editions, including Ming-dynasty block-printed edition, Japanese and Korean block-printed edition, old hand-copied edition and modern printing edition. For Wu zhu su wen, there were 5 editions, Ming-Qing-dynasty block-printed edition, Japanese block-printed edition, old hand-copied edition, photocopy and modern edition. For Zhen fang liu ji, there were Ming-dynasty block-printed edition, hand-copied edition, photocopy and modern edition. Mai yu always was printed together with Yi fang kao, and its editions were same as those of Yi fang kao, except some modern printing edition with Mai yu excluded. PMID:24135480

  10. Extracting the Textual and Temporal Structure of Supercomputing Logs

    SciTech Connect

    Jain, S; Singh, I; Chandra, A; Zhang, Z; Bronevetsky, G

    2009-05-26

    Supercomputers are prone to frequent faults that adversely affect their performance, reliability and functionality. System logs collected on these systems are a valuable resource of information about their operational status and health. However, their massive size, complexity, and lack of standard format makes it difficult to automatically extract information that can be used to improve system management. In this work we propose a novel method to succinctly represent the contents of supercomputing logs, by using textual clustering to automatically find the syntactic structures of log messages. This information is used to automatically classify messages into semantic groups via an online clustering algorithm. Further, we describe a methodology for using the temporal proximity between groups of log messages to identify correlated events in the system. We apply our proposed methods to two large, publicly available supercomputing logs and show that our technique features nearly perfect accuracy for online log-classification and extracts meaningful structural and temporal message patterns that can be used to improve the accuracy of other log analysis techniques.

  11. Fusion of Laboratory and Textual Data for Investigative Bioforensics

    SciTech Connect

    Webb-Robertson, Bobbie-Jo M.; Corley, Courtney D.; McCue, Lee Ann; Wahl, Karen L.; Kreuzer, Helen W.

    2013-03-10

    Chemical and biological forensic programs focus on the identification of a threat and acquisition of laboratory measurements to determine how a threat agent may have been produced. However, to generate investigative leads, it might also be useful to identify institutions where the same agent has been produced by the same or a very similar process, since the producer of the agent may have learned methods at a university or similar institution. We have developed a Bayesian network framework that fuses hard and soft data sources to assign probability to production practices. It combines the results of laboratory measurements with an automatic text reader to scan scientific literature and rank institutions that had published papers on the agent of interest in order of the probability that the institution has the capability to generate the sample of interest based on laboratory data. We demonstrate the Bayesian network on an example case from microbial forensics, predicting the methods used to produce Bacillus anthracis spores based on mass spectrometric measurements and identifying institutions that have a history of growing Bacillus spores using the same or highly similar methods. We illustrate that the network model can assign a higher posterior probability than expected by random chance to appropriate institutions when trained using only a small set of manually analyzed documents. This is the first example of an automated methodology to integrate experimental and textual data for the purpose of investigative forensics.

  12. Experiential thinking in creationism--a textual analysis.

    PubMed

    Nieminen, Petteri; Ryökäs, Esko; Mustonen, Anne-Mari

    2015-01-01

    Creationism is a religiously motivated worldview in denial of biological evolution that has been very resistant to change. We performed a textual analysis by examining creationist and pro-evolutionary texts for aspects of "experiential thinking", a cognitive process different from scientific thought. We observed characteristics of experiential thinking as follows: testimonials (present in 100% of sampled creationist texts), such as quotations, were a major form of proof. Confirmation bias (100% of sampled texts) was represented by ignoring or dismissing information that would contradict the creationist hypothesis. Scientifically irrelevant or flawed information was re-interpreted as relevant for the falsification of evolution (75-90% of sampled texts). Evolutionary theory was associated to moral issues by demonizing scientists and linking evolutionary theory to atrocities (63-93% of sampled texts). Pro-evolutionary rebuttals of creationist claims also contained testimonials (93% of sampled texts) and referred to moral implications (80% of sampled texts) but displayed lower prevalences of stereotypical thinking (47% of sampled texts), confirmation bias (27% of sampled texts) and pseudodiagnostics (7% of sampled texts). The aspects of experiential thinking could also be interpreted as argumentative fallacies. Testimonials lead, for instance, to ad hominem and appeals to authorities. Confirmation bias and simplification of data give rise to hasty generalizations and false dilemmas. Moral issues lead to guilt by association and appeals to consequences. Experiential thinking and fallacies can contribute to false beliefs and the persistence of the claims. We propose that science educators would benefit from the systematic analysis of experiential thinking patterns and fallacies in creationist texts and pro-evolutionary rebuttals in order to concentrate on scientific misconceptions instead of the scientifically irrelevant aspects of the creationist-evolutionist debate. PMID:25734650

  13. Experiential Thinking in Creationism—A Textual Analysis

    PubMed Central

    Nieminen, Petteri; Ryökäs, Esko; Mustonen, Anne-Mari

    2015-01-01

    Creationism is a religiously motivated worldview in denial of biological evolution that has been very resistant to change. We performed a textual analysis by examining creationist and pro-evolutionary texts for aspects of “experiential thinking”, a cognitive process different from scientific thought. We observed characteristics of experiential thinking as follows: testimonials (present in 100% of sampled creationist texts), such as quotations, were a major form of proof. Confirmation bias (100% of sampled texts) was represented by ignoring or dismissing information that would contradict the creationist hypothesis. Scientifically irrelevant or flawed information was re-interpreted as relevant for the falsification of evolution (75–90% of sampled texts). Evolutionary theory was associated to moral issues by demonizing scientists and linking evolutionary theory to atrocities (63–93% of sampled texts). Pro-evolutionary rebuttals of creationist claims also contained testimonials (93% of sampled texts) and referred to moral implications (80% of sampled texts) but displayed lower prevalences of stereotypical thinking (47% of sampled texts), confirmation bias (27% of sampled texts) and pseudodiagnostics (7% of sampled texts). The aspects of experiential thinking could also be interpreted as argumentative fallacies. Testimonials lead, for instance, to ad hominem and appeals to authorities. Confirmation bias and simplification of data give rise to hasty generalizations and false dilemmas. Moral issues lead to guilt by association and appeals to consequences. Experiential thinking and fallacies can contribute to false beliefs and the persistence of the claims. We propose that science educators would benefit from the systematic analysis of experiential thinking patterns and fallacies in creationist texts and pro-evolutionary rebuttals in order to concentrate on scientific misconceptions instead of the scientifically irrelevant aspects of the creationist—evolutionist debate. PMID:25734650

  14. Textrous!: Extracting Semantic Textual Meaning from Gene Sets

    PubMed Central

    Daimon, Caitlin M.; Siddiqui, Sana; Luttrell, Louis M.; Maudsley, Stuart

    2013-01-01

    The un-biased and reproducible interpretation of high-content gene sets from large-scale genomic experiments is crucial to the understanding of biological themes, validation of experimental data, and the eventual development of plans for future experimentation. To derive biomedically-relevant information from simple gene lists, a mathematical association to scientific language and meaningful words or sentences is crucial. Unfortunately, existing software for deriving meaningful and easily-appreciable scientific textual ‘tokens’ from large gene sets either rely on controlled vocabularies (Medical Subject Headings, Gene Ontology, BioCarta) or employ Boolean text searching and co-occurrence models that are incapable of detecting indirect links in the literature. As an improvement to existing web-based informatic tools, we have developed Textrous!, a web-based framework for the extraction of biomedical semantic meaning from a given input gene set of arbitrary length. Textrous! employs natural language processing techniques, including latent semantic indexing (LSI), sentence splitting, word tokenization, parts-of-speech tagging, and noun-phrase chunking, to mine MEDLINE abstracts, PubMed Central articles, articles from the Online Mendelian Inheritance in Man (OMIM), and Mammalian Phenotype annotation obtained from Jackson Laboratories. Textrous! has the ability to generate meaningful output data with even very small input datasets, using two different text extraction methodologies (collective and individual) for the selecting, ranking, clustering, and visualization of English words obtained from the user data. Textrous!, therefore, is able to facilitate the output of quantitatively significant and easily appreciable semantic words and phrases linked to both individual gene and batch genomic data. PMID:23646135

  15. Utility-preserving privacy protection of textual healthcare documents.

    PubMed

    Sánchez, David; Batet, Montserrat; Viejo, Alexandre

    2014-12-01

    The adoption of ITs by medical organisations makes possible the compilation of large amounts of healthcare data, which are quite often needed to be released to third parties for research or business purposes. Many of this data are of sensitive nature, because they may include patient-related documents such as electronic healthcare records. In order to protect the privacy of individuals, several legislations on healthcare data management, which state the kind of information that should be protected, have been defined. Traditionally, to meet with current legislations, a manual redaction process is applied to patient-related documents in order to remove or black-out sensitive terms. This process is costly and time-consuming and has the undesired side effect of severely reducing the utility of the released content. Automatic methods available in the literature usually propose ad-hoc solutions that are limited to protect specific types of structured information (e.g. e-mail addresses, social security numbers, etc.); as a result, they are hardly applicable to the sensitive entities stated in current regulations that do not present those structural regularities (e.g. diseases, symptoms, treatments, etc.). To tackle these limitations, in this paper we propose an automatic sanitisation method for textual medical documents (e.g. electronic healthcare records) that is able to protect, regardless of their structure, sensitive entities (e.g. diseases) and also those semantically related terms (e.g. symptoms) that may disclose the former ones. Contrary to redaction schemes based on term removal, our approach improves the utility of the protected output by replacing sensitive terms with appropriate generalisations retrieved from several medical and general-purpose knowledge bases. Experiments conducted on highly sensitive documents and in coherency with current regulations on healthcare data privacy show promising results in terms of the practical privacy and utility of the protected output. PMID:24998814

  16. A Dynamic Ensemble Framework for Mining Textual Streams with Class Imbalance

    PubMed Central

    Song, Ge

    2014-01-01

    Textual stream classification has become a realistic and challenging issue since large-scale, high-dimensional, and non-stationary streams with class imbalance have been widely used in various real-life applications. According to the characters of textual streams, it is technically difficult to deal with the classification of textual stream, especially in imbalanced environment. In this paper, we propose a new ensemble framework, clustering forest, for learning from the textual imbalanced stream with concept drift (CFIM). The CFIM is based on ensemble learning by integrating a set of clustering trees (CTs). An adaptive selection method, which flexibly chooses the useful CTs by the property of the stream, is presented in CFIM. In particular, to deal with the problem of class imbalance, we collect and reuse both rare-class instances and misclassified instances from the historical chunks. Compared to most existing approaches, it is worth pointing out that our approach assumes that both majority class and rareclass may suffer from concept drift. Thus the distribution of resampled instances is similar to the current concept. The effectiveness of CFIM is examined in five real-world textual streams under an imbalanced nonstationary environment. Experimental results demonstrate that CFIM achieves better performance than four state-of-the-art ensemble models. PMID:24982961

  17. A dynamic ensemble framework for mining textual streams with class imbalance.

    PubMed

    Song, Ge; Ye, Yunming

    2014-01-01

    Textual stream classification has become a realistic and challenging issue since large-scale, high-dimensional, and non-stationary streams with class imbalance have been widely used in various real-life applications. According to the characters of textual streams, it is technically difficult to deal with the classification of textual stream, especially in imbalanced environment. In this paper, we propose a new ensemble framework, clustering forest, for learning from the textual imbalanced stream with concept drift (CFIM). The CFIM is based on ensemble learning by integrating a set of clustering trees (CTs). An adaptive selection method, which flexibly chooses the useful CTs by the property of the stream, is presented in CFIM. In particular, to deal with the problem of class imbalance, we collect and reuse both rare-class instances and misclassified instances from the historical chunks. Compared to most existing approaches, it is worth pointing out that our approach assumes that both majority class and rareclass may suffer from concept drift. Thus the distribution of resampled instances is similar to the current concept. The effectiveness of CFIM is examined in five real-world textual streams under an imbalanced nonstationary environment. Experimental results demonstrate that CFIM achieves better performance than four state-of-the-art ensemble models. PMID:24982961

  18. Combining textual and visual information for image retrieval in the medical domain.

    PubMed

    Gkoufas, Yiannis; Morou, Anna; Kalamboukis, Theodore

    2011-01-01

    In this article we have assembled the experience obtained from our participation in the imageCLEF evaluation task over the past two years. Exploitation on the use of linear combinations for image retrieval has been attempted by combining visual and textual sources of images. From our experiments we conclude that a mixed retrieval technique that applies both textual and visual retrieval in an interchangeably repeated manner improves the performance while overcoming the scalability limitations of visual retrieval. In particular, the mean average precision (MAP) has increased from 0.01 to 0.15 and 0.087 for 2009 and 2010 data, respectively, when content-based image retrieval (CBIR) is performed on the top 1000 results from textual retrieval based on natural language processing (NLP). PMID:22163261

  19. The Effects of Textual Prompting and Reading Fluency on the Acquisition of Intraverbals

    PubMed Central

    Emmick, Jill R; Cihon, Traci M; Eshleman, John W

    2010-01-01

    The study examined the effects of textual prompt fading on the acquisition of intraverbals in 3 individuals with developmental disabilities. An alternating treatments design was used to assess the two independent variables. The first independent variable was transfer of stimulus control without component skill fluency. The second independent variable was transfer of stimulus control with component skill fluency, in which participants were taught the textual responses used in the scripts to a level of fluency prior to transfer of stimulus control. The results suggest that transfer of stimulus control was effective for teaching intraverbals and that adding a fluency component resulted in faster acquisition for some participants. PMID:22477460

  20. Predicting Learning-Related Emotions from Students' Textual Classroom Feedback via Twitter

    ERIC Educational Resources Information Center

    Altrabsheh, Nabeela; Cocea, Mihaela; Fallahkhair, Sanaz

    2015-01-01

    Teachers/lecturers typically adapt their teaching to respond to students' emotions, e.g. provide more examples when they think the students are confused. While getting a feel of the students' emotions is easier in small settings, it is much more difficult in larger groups. In these larger settings textual feedback from students could provide…

  1. Information Structure and Practice as Facilitators of Deaf Users' Navigation in Textual Websites

    ERIC Educational Resources Information Center

    Fajardo, I.; Canas, J. J.; Salmeron, L.; Abascal, J.

    2009-01-01

    Deaf users might find it difficult to navigate through websites with textual content which, for many of them, constitutes the written representation of a non-native oral language. With the aim of testing how the information structure could compensate for this difficulty, 27 prelingual deaf users of sign language were asked to search a set of…

  2. The Illusion of Inclusion: A Critical Race Theory Textual Analysis of Race and Standards

    ERIC Educational Resources Information Center

    Heilig, Julian Vasquez; Brown, Keffrelyn D.; Brown, Anthony L.

    2012-01-01

    In this article, Julian Vasquez Heilig, Keffrelyn Brown, and Anthony Brown offer findings from a close textual analysis of how the Texas social studies standards address race, racism, and communities of color. Using the lens of critical race theory, the authors uncover the sometimes subtle ways that the standards can appear to adequately address

  3. Game Design as Textual Poaching: Media Literacy, Creativity and Game-Making

    ERIC Educational Resources Information Center

    Pelletier, Caroline; Burn, Andrew; Buckingham, David

    2010-01-01

    This article addresses practices of textual appropriation in computer games made by young people. By focusing on how young people's production work makes reference to popular media texts, it examines the basis on which such work claims to be legible as a game text: how it claims to be literate in the context of an after-school game-making club.

  4. Analyzing Student Performance and Attitudes toward Textual versus Iconic Programming Languages

    ERIC Educational Resources Information Center

    Lin, Janet Mei-Chuen; Yang, Mei-Ching

    2009-01-01

    In this study half of 52 sixth graders learned to program in MSWLogo and the other half in Drape. An analysis of students' test scores revealed that Drape (an iconic language) seemed to have a steeper learning curve than MSWLogo (a textual language). However, as students gradually became more familiar with either language, the difference in…

  5. Students' Mind Wandering in Macroscopic and Submicroscopic Textual Narrations and Its Relationship with Their Reading Comprehension

    ERIC Educational Resources Information Center

    Al-Balushi, Sulaiman M.; Al-Harthy, Ibrahim S.

    2015-01-01

    The aim of the current study was to investigate students' mind wandering while reading different types of textual narrations (macroscopic and submicroscopic) in chemistry. Another goal was to determine the relationship between mind wandering and students' reading comprehension. The participants were 65 female ninth grade students in Oman. Using a…

  6. Teach for America's Long Arc: A Critical Race Theory Textual Analysis of Wendy Kopp's Works

    ERIC Educational Resources Information Center

    Barnes, Michael C.; Germain, Emily K.; Valenzuela, Angela

    2016-01-01

    We read and analyzed 165,000 words and uncover a series of counter-stories buried within a textual corpus, authored by Teach For America (TFA) founder Wendy Kopp (Kopp, 1989, 2001; Kopp & Farr, 2011), that offers insight into the forms of racism endemic to Teach For America. All three counter-stories align with a critical race theory (CRT)…

  7. The Illusion of Inclusion: A Critical Race Theory Textual Analysis of Race and Standards

    ERIC Educational Resources Information Center

    Heilig, Julian Vasquez; Brown, Keffrelyn D.; Brown, Anthony L.

    2012-01-01

    In this article, Julian Vasquez Heilig, Keffrelyn Brown, and Anthony Brown offer findings from a close textual analysis of how the Texas social studies standards address race, racism, and communities of color. Using the lens of critical race theory, the authors uncover the sometimes subtle ways that the standards can appear to adequately address…

  8. Textual Enhancement of Two L2 Arabic Forms: A Classroom-Based Study

    ERIC Educational Resources Information Center

    Park, Eun Sung; Nassif, Lama

    2014-01-01

    Research on textual enhancement (TE) has given rise to several factors that may play a role in generating learners' noticing of target forms, one of which pertains to the nature of the target form(s). In particular, results have suggested that learners are more likely to notice more meaning-bearing forms than less meaning-bearing forms.

  9. Analyzing Student Performance and Attitudes toward Textual versus Iconic Programming Languages

    ERIC Educational Resources Information Center

    Lin, Janet Mei-Chuen; Yang, Mei-Ching

    2009-01-01

    In this study half of 52 sixth graders learned to program in MSWLogo and the other half in Drape. An analysis of students' test scores revealed that Drape (an iconic language) seemed to have a steeper learning curve than MSWLogo (a textual language). However, as students gradually became more familiar with either language, the difference in

  10. Textual Enhancement of Two L2 Arabic Forms: A Classroom-Based Study

    ERIC Educational Resources Information Center

    Park, Eun Sung; Nassif, Lama

    2014-01-01

    Research on textual enhancement (TE) has given rise to several factors that may play a role in generating learners' noticing of target forms, one of which pertains to the nature of the target form(s). In particular, results have suggested that learners are more likely to notice more meaning-bearing forms than less meaning-bearing forms.…

  11. Arguing in L2: Discourse Structure and Textual Metadiscourse in Philippine Newspaper Editorials

    ERIC Educational Resources Information Center

    Tarrayo, Veronico N.; Duque, Marie Claire T.

    2011-01-01

    This study described the discourse structure and textual metadiscourse in newspaper editorials in the Philippines where English is used as a second language or L2. Specifically, it sought answers to the following questions: (1) What discourse features characterize the structure of the following parts of Philippine newspaper editorials--orientation…

  12. The Effect of Textual Metafunction on the Iranian EFL Learners' Writing Performance

    ERIC Educational Resources Information Center

    Paziraie, Mandana Eftekhar

    2013-01-01

    This study is devoted to the effect of "textual metafunction" on the levels of coherence and cohesion in the Iranian EFL learners' English writing performance. Sixty Iranian intermediate EFL learners who were adult females participated in this study were randomly divided into two groups; experimental, and control. They were given a…

  13. Textual Trouble in River City: Literacy, Rhetoric, and Consumerism in "The Music Man."

    ERIC Educational Resources Information Center

    Malinowitz, Harriet

    1999-01-01

    Offers a reading of "The Music Man" that traces the ways its charm and humor are undergirded by a parodic stance toward American values as rooted in turn-of-the-century discourses of literacy, education, morality, and in the simultaneously burgeoning national obsessing with buying and selling. Considers sexual and textual anxieties in the…

  14. Students' Proficiency and Textual Computer Gloss Use in Facilitating Vocabulary Knowledge

    ERIC Educational Resources Information Center

    Yusuf, Mohamad A.; Sim, Tam S.; Su'ad A.

    2014-01-01

    Learning vocabulary forms a major part for any language learner. Apart from direct teaching of vocabulary, language teachers are always searching for ways to increase their students' vocabulary to enable them to use the language more effectively. Therefore, this study sets out to investigate whether the use of computer textual glosses can aid…

  15. Complexities and Dynamics of Korean Graduate Students' Textual Borrowing in Academic Writing

    ERIC Educational Resources Information Center

    Rhee, Eunsook Ha

    2010-01-01

    Academic writing in U.S. higher education often involves textual borrowing, referred to as the integration and documentation of reading sources and carried out with summaries, quotes, and paraphrases. Second language (L2) English students are likely to use sources inappropriately and consequentially are accused of plagiarism based on university…

  16. Discourses of Plagiarism: Moralist, Proceduralist, Developmental and Inter-Textual Approaches

    ERIC Educational Resources Information Center

    Kaposi, David; Dell, Pippa

    2012-01-01

    This paper reconstructs prevalent academic discourses of student plagiarism: moralism, proceduralism, development, and writing/inter-textuality. It approaches the discourses from three aspects: intention, interpretation and the nature of the academic community. It argues that the assumptions of the moralistic approach regarding suspect intention,

  17. Exploring "Girl Power": Gender, Literacy and the Textual Practices of Young Women Attending an Elite School

    ERIC Educational Resources Information Center

    Charles, Claire

    2007-01-01

    Popular discourses concerning the relationship between gender and academic literacies have suggested that boys are lacking in particular, school-based literacy competencies compared with girls. Such discourses construct "gender" according to a binary framework and they obscure the way in which literacy and textual practices operate as a site in…

  18. Game Design as Textual Poaching: Media Literacy, Creativity and Game-Making

    ERIC Educational Resources Information Center

    Pelletier, Caroline; Burn, Andrew; Buckingham, David

    2010-01-01

    This article addresses practices of textual appropriation in computer games made by young people. By focusing on how young people's production work makes reference to popular media texts, it examines the basis on which such work claims to be legible as a game text: how it claims to be literate in the context of an after-school game-making club.…

  19. Textual Enhancements and Comprehension with Adult Readers of English in China

    ERIC Educational Resources Information Center

    Brantmeier, Cindy; Callender, Aimee; Yu, Xiucheng; McDaniel, Mark

    2012-01-01

    The present study utilizes texts from social psychology to examine the effects of textual enhancements on reading comprehension with 185 native adult Chinese speakers learning English in China. Participants read two different vignettes, either with or without an adjunct. Each adjunct consisted of a "what" question along with instructions to either…

  20. Anatomy of a Masterpiece: A Close Textual Analysis of Abraham Lincoln's Second Inaugural Address.

    ERIC Educational Resources Information Center

    Slagell, Amy R.

    1991-01-01

    States that Abraham Lincoln's second inaugural address is a recognized rhetorical masterpiece. Accounts for this recognition by examining the text microscopically. Uses the method of close textual analysis that explores the inner workings of the text to discover the complexity of Lincoln's masterwork. (PRA)

  1. The Investigation of Power in Written Texts through the Use of Multiple Textual Analytic Frames

    ERIC Educational Resources Information Center

    Wickens, Corrine M.

    2011-01-01

    Although often used as secondary sources, written texts are powerful sources of data for qualitative researchers to explore power networks and broad ideological perspectives. As such, I present in this paper an analytic process that draws upon multiple analytic frameworks--constant comparative analysis, discursive textual analysis, and traditional…

  2. Tonal Interface to MacroMolecules (TIMMol): A Textual and Tonal Tool for Molecular Visualization

    ERIC Educational Resources Information Center

    Cordes, Timothy J.; Carlson, C. Britt; Forest, Katrina T.

    2008-01-01

    We developed the three-dimensional visualization software, Tonal Interface to MacroMolecules or TIMMol, for studying atomic coordinates of protein structures. Key features include audio tones indicating x, y, z location, identification of the cursor location in one-dimensional and three-dimensional space, textual output that can be easily linked…

  3. PISA Test Items and School Textbooks Related to Science: A Textual Comparison

    ERIC Educational Resources Information Center

    Hatzinikita, Vassilia; Dimopoulos, Kostas; Christidou, Vasilia

    2008-01-01

    The paper compares the nature of the textual construction of the Programme for International Student Assessment (PISA) science test items and the Greek school science textbooks. This nature is determined by the interplay of the notions of classification (content specialization) and formality (code specialization) modulated by both the linguistic…

  4. Establishing Textual Authority and Separating Voices: A New Approach to Teaching Referencing

    ERIC Educational Resources Information Center

    Mott-Smith, Jennifer A.

    2011-01-01

    In this article the author discusses a new approach to teaching referencing based on establishing textual authority and separating writers' voices. She first presents a short discussion of key theoretical ideas that inform the approach, and then she describes five lessons, four of which are integrated into the course theme of "homelessness."…

  5. A New Framework for Textual Information Mining over Parse Trees. CRESST Report 805

    ERIC Educational Resources Information Center

    Mousavi, Hamid; Kerr, Deirdre; Iseli, Markus R.

    2011-01-01

    Textual information mining is a challenging problem that has resulted in the creation of many different rule-based linguistic query languages. However, these languages generally are not optimized for the purpose of text mining. In other words, they usually consider queries as individuals and only return raw results for each query. Moreover they…

  6. Tonal Interface to MacroMolecules (TIMMol): A Textual and Tonal Tool for Molecular Visualization

    ERIC Educational Resources Information Center

    Cordes, Timothy J.; Carlson, C. Britt; Forest, Katrina T.

    2008-01-01

    We developed the three-dimensional visualization software, Tonal Interface to MacroMolecules or TIMMol, for studying atomic coordinates of protein structures. Key features include audio tones indicating x, y, z location, identification of the cursor location in one-dimensional and three-dimensional space, textual output that can be easily linked

  7. Framing Student Evaluations of University Learning and Teaching: Discursive Strategies and Textual Outcomes

    ERIC Educational Resources Information Center

    Ryan, Mary

    2015-01-01

    Evaluation in higher education is an evolving social practice; that is, it involves what people, institutions and broader systems do and say, how they do and say it, what they value, the effects of these practices and values, and how meanings are ascribed. The textual products (verbal, written, visual and gestural) that inform and are produced by,…

  8. Effects of Textual and Animated Orienting Activities and Practice on Learning from Computer-Based Instruction.

    ERIC Educational Resources Information Center

    Rieber, Lloyd P.; Hannafin, Michael J.

    1988-01-01

    Describes study designed to examine the effects of textual and/or computer animated orienting strategies and practice on rule-using and problem-solving skills of elementary school students using computer-assisted instruction. Four different versions of a lesson based on Isaac Newton's Law of Motion are described, and results are analyzed. (28…

  9. Information Structure and Practice as Facilitators of Deaf Users' Navigation in Textual Websites

    ERIC Educational Resources Information Center

    Fajardo, I.; Canas, J. J.; Salmeron, L.; Abascal, J.

    2009-01-01

    Deaf users might find it difficult to navigate through websites with textual content which, for many of them, constitutes the written representation of a non-native oral language. With the aim of testing how the information structure could compensate for this difficulty, 27 prelingual deaf users of sign language were asked to search a set of

  10. Rereading Dis/Ability in Adolescent Literature: Textual Invitation & Repertoires in Reader Response

    ERIC Educational Resources Information Center

    Walker, Valerie Struthers

    2009-01-01

    This dissertation draws on textual reader response theory and humanities-based Disability Studies theories to explores the ways in which preservice teachers participating in a course called "Issues of Diversity in Children's and Adolescent Literature" and their instructor, who is also the researcher, made sense of representations of disability in…

  11. Students' Mind Wandering in Macroscopic and Submicroscopic Textual Narrations and Its Relationship with Their Reading Comprehension

    ERIC Educational Resources Information Center

    Al-Balushi, Sulaiman M.; Al-Harthy, Ibrahim S.

    2015-01-01

    The aim of the current study was to investigate students' mind wandering while reading different types of textual narrations (macroscopic and submicroscopic) in chemistry. Another goal was to determine the relationship between mind wandering and students' reading comprehension. The participants were 65 female ninth grade students in Oman. Using a

  12. Effects of Textual Enhancement and Input Enrichment on L2 Development

    ERIC Educational Resources Information Center

    Rassaei, Ehsan

    2015-01-01

    Research on second language (L2) acquisition has recently sought to include formal instruction into second and foreign language classrooms in a more unobtrusive and implicit manner. Textual enhancement and input enrichment are two techniques which are aimed at drawing learners' attention to specific linguistic features in input and at the same…

  13. A Comparison of Content Schemata and Textual Schemata or the Process of Parachuting.

    ERIC Educational Resources Information Center

    Bowman, Margie

    1981-01-01

    Examines the background of schema theory and discusses the contention that content schemata is more important to the reader than textual schemata. Concludes that the more useful schemata is determined by the context rather than one schemata type always being more important than the other. (FL)

  14. The Investigation of Power in Written Texts through the Use of Multiple Textual Analytic Frames

    ERIC Educational Resources Information Center

    Wickens, Corrine M.

    2011-01-01

    Although often used as secondary sources, written texts are powerful sources of data for qualitative researchers to explore power networks and broad ideological perspectives. As such, I present in this paper an analytic process that draws upon multiple analytic frameworks--constant comparative analysis, discursive textual analysis, and traditional

  15. Written Textual Production and Consumption (WTPC) in Vernacular and English-Medium Settings in Gujarat, India.

    ERIC Educational Resources Information Center

    Ramanathan, Vaidehi

    2003-01-01

    Sketches key facets in the larger socioeducational machinery that shapes the written textual production and consumption (WTPC) of English-medium (EM) and "vernacular-medium" (VM) students in Gujarat, India. Lays out ways in which articulator macro-structures align together to produce and shape conditions that privilege the WTPC of EM students over

  16. Perceptions and Beliefs about Textual Appropriation and Source Use in Second Language Writing

    ERIC Educational Resources Information Center

    Polio, Charlene; Shi, Ling

    2012-01-01

    Perceptions and judgments on plagiarism or acceptable use of source texts are contingent on one's interpretations and experiences in reading and writing academic texts in a specific disciplinary context. The lack of consensus on what is acceptable textual appropriation in student writing has led to the scholarship on perceptions of textual…

  17. Discourses of Plagiarism: Moralist, Proceduralist, Developmental and Inter-Textual Approaches

    ERIC Educational Resources Information Center

    Kaposi, David; Dell, Pippa

    2012-01-01

    This paper reconstructs prevalent academic discourses of student plagiarism: moralism, proceduralism, development, and writing/inter-textuality. It approaches the discourses from three aspects: intention, interpretation and the nature of the academic community. It argues that the assumptions of the moralistic approach regarding suspect intention,…

  18. Atlas del Genoma del Cáncer: Antecedentes

    Cancer.gov

    El Atlas del Genoma del Cáncer es una iniciativa de los Institutos Nacionales de la Salud (NIH) para crear mapas multidimensionales completos de los cambios genómicos clave en los tipos y subtipos principales de cáncer.

  19. Vacunas contra los virus del papiloma humano

    Cancer.gov

    Una hoja informativa acerca de las vacunas contra los virus del papiloma humano (VPH) para prevenir infecciones con ciertos tipos de VPH, los cuales son la causa principal del cáncer de cuello del útero o cérvix.

  20. Automatic textual annotation of video news based on semantic visual object extraction

    NASA Astrophysics Data System (ADS)

    Boujemaa, Nozha; Fleuret, Francois; Gouet, Valerie; Sahbi, Hichem

    2003-12-01

    In this paper, we present our work for automatic generation of textual metadata based on visual content analysis of video news. We present two methods for semantic object detection and recognition from a cross modal image-text thesaurus. These thesaurus represent a supervised association between models and semantic labels. This paper is concerned with two semantic objects: faces and Tv logos. In the first part, we present our work for efficient face detection and recogniton with automatic name generation. This method allows us also to suggest the textual annotation of shots close-up estimation. On the other hand, we were interested to automatically detect and recognize different Tv logos present on incoming different news from different Tv Channels. This work was done jointly with the French Tv Channel TF1 within the "MediaWorks" project that consists on an hybrid text-image indexing and retrieval plateform for video news.

  1. Textual alchemy: the transformation of pseudo-Albertus Magnus's Semita recta into the Mirror of Lights.

    PubMed

    Grund, Peter

    2009-11-01

    This article explores the strategies of and the reasons behind the reworking of pseudo-Albertus Magnus's Semita recta into the Mirror of Lights. I argue that the redactor sought to provide a more comprehensive defence of the legitimacy of alchemy than found in the Semita recta. In the process of doing so, he reshaped the original text so as to present three units that addressed different parts of the alchemical opus: first, theory and justification of alchemy; second, basic information on substances and procedures; and, third, practice. The redactor employed sophisticated textual tools identical to those seen in scholastic texts. These strategies, I argue, constitute part of the redactor's attempt to bring authority and credibility to his project and to alchemy in general. Certainly, much more attention needs to be paid to these experiments of textual alchemy in order to understand the practice of alchemy in the late medieval period. PMID:20506702

  2. Knowledge Discovery in Textual Databases: A Concept-Association Mining Approach

    NASA Astrophysics Data System (ADS)

    Mete, Mutlu; Yuruk, Nurcan; Xu, Xiaowei; Berleant, Daniel

    The number of scientific publications is exploding as online digital libraries and the World Wide Web grow. MEDLINE, the premier bibliographic database of the National Library of Medicine (NLM) , contains about 18 million records from more than 7,300 different publications dating from 1965; it is growing by about 400,000 citations each year. The explosive growth of information in textual documents creates great need for techniques for knowledge discovery from text collections.

  3. Knowledge Discovery in Textual Databases: A Concept-Association Mining Approach

    NASA Astrophysics Data System (ADS)

    Mete, Mutlu; Yuruk, Nurcan; Xu, Xiaowei; Berleant, Daniel

    The number of scientific publications is exploding as online digital libraries and the World Wide Web grow. MEDLINE, the premier bibliographic database of the National Library of Medicine (NLM), contains about 18 million records from more than 7,300 different publications dating from 1965; it is growing by about 400,000 citations each year. The explosive growth of information in textual documents creates great need for techniques for knowledge discovery from text collections.

  4. Flight Deck Data Link Displays: An Evaluation of Textual and Graphical Implementations

    NASA Technical Reports Server (NTRS)

    McGann, Alison; Lozito, Sandy; Corker, Kevin; Ashford, Rose (Technical Monitor)

    2001-01-01

    In Experiment 1, 16 pilots participated in a part-task simulation study that evaluated pilot data link communication for short and long message types and for two textual formats. No differences were found between the two textual formats when evaluating data link transaction times and pilot performance on a secondary task. Pilots initiated flight changes more quickly with the T-Scan format, where location of clearance information roughly corresponded to the cockpit instrument layout. Longer messages were less problematic than two short messages sent in close succession as pilots required more verbal clarification for closely spaced messages. 24 pilots participated in a second experiment that evaluated pilot communication performance for textual data link, two implementations of graphical data link, and a combined graphical and textual information modality. The two modalities incorporating text resulted in significantly faster transaction times and better performance on the secondary task than the two graphical-only implementations. The interval between messages was also more systematically varied in Experiment 2, and a short interval between messages significantly increased the access time for the second message. This delay in access was long enough to increase significantly the total transaction time of the second message, and this effect was exaggerated for the graphical-only implementations. Time to view the message before acknowledgement and time to initiate flight changes were not affected by the interval manipulation, This suggests that pilots adopt a sequential message handling strategy, and presenting messages closely in succession may present operational problems in a data link Air Traffic Control (ATC) environment. The results of this study also indicate that the perceived importance of message content is currently a crucial element in pilot data link communication.

  5. Improved medical image modality classification using a combination of visual and textual features.

    PubMed

    Dimitrovski, Ivica; Kocev, Dragi; Kitanovski, Ivan; Loskovska, Suzana; Džeroski, Sašo

    2015-01-01

    In this paper, we present the approach that we applied to the medical modality classification tasks at the ImageCLEF evaluation forum. More specifically, we used the modality classification databases from the ImageCLEF competitions in 2011, 2012 and 2013, described by four visual and one textual types of features, and combinations thereof. We used local binary patterns, color and edge directivity descriptors, fuzzy color and texture histogram and scale-invariant feature transform (and its variant opponentSIFT) as visual features and the standard bag-of-words textual representation coupled with TF-IDF weighting. The results from the extensive experimental evaluation identify the SIFT and opponentSIFT features as the best performing features for modality classification. Next, the low-level fusion of the visual features improves the predictive performance of the classifiers. This is because the different features are able to capture different aspects of an image, their combination offering a more complete representation of the visual content in an image. Moreover, adding textual features further increases the predictive performance. Finally, the results obtained with our approach are the best results reported on these databases so far. PMID:24997992

  6. Using Semantic Web technology to support icd-11 textual definitions authoring

    PubMed Central

    2013-01-01

    The beta phase of the 11th revision of International Classification of Diseases (ICD-11) intends to accept public input through a distributed model of authoring. One of the core use cases is to create textual definitions for the ICD categories. The objective of the present study is to design, develop, and evaluate approaches to support ICD-11 textual definitions authoring using Semantic Web technology. We investigated a number of heterogeneous resources related to the definitions of diseases, including the linked open data (LOD) from DBpedia, the textual definitions from the Unified Medical Language System (UMLS) and the formal definitions of the Systematized Nomenclature of MedicineClinical Terms (SNOMED CT). We integrated them in a Semantic Web framework (i.e., the Linked Data in a Resource Description Framework [RDF] triple store), which is being proposed as a backend in a prototype platform for collaborative authoring of ICD-11 beta. We performed a preliminary evaluation on the usefulness of our approaches and discussed the potential challenges from both technical and clinical perspectives. PMID:23601451

  7. Insights triggered by textual micro-counseling dialogues of restructuring orientation in experts and students.

    PubMed

    Yu, Fei; Zhang, Wencai; Zhang, Zhijie; Zhang, Jianxin; Luo, Jing

    2016-03-01

    Insight is a salient psychotherapeutic progress but has rarely been measured in a controlled experimental setting. This study aimed to assess whether textual micro-counseling dialogue could validly evoke insight and to explore the characteristics of insight. The guessing riddle of cognitive psychology was used as a reference of the experimental paradigm. Specifically, textual micro-counseling dialogues applying cognitive restructuring techniques were presented. The participant first read a description of a psychological distress ("problem") and then an explanation ("solution"). Zero-, low-, and high-restructuring solutions were randomly matched to the problems and it was expected that they would trigger different levels of insight experiences. Experts and students evaluated the adaptability and emotional valence of problems, and the insightfulness, novelty, adaptability, and emotional valence of solutions. For both experts and students, different intensities of insightfulness were produced across high-, low- and zero-restructuring solutions. Novelty significantly discriminated the high-restructuring solutions from the other two solution types. Adaptability and emotional valence could discriminate the high- and low-restructuring solutions types from the zero-restructuring solution. Insightfulness had high correlations with novelty and adaptability. These results indicated that textual micro-counseling dialogues with a high-restructuring solution could validly produce the greatest insightfulness and the features of high-restructuring solutions may have reference meaning for improving psychotherapeutic effect. PMID:26377623

  8. Tipos de cáncer

    Cancer.gov

    Lista alfabética de todos los tipos de cáncer con enlaces a enfermedades específicas e información general sobre tratamiento, cuidados de apoyo, exámenes de detección, prevención, estudios clínicos y otros temas.

  9. Integrating Ontological Knowledge and Textual Evidence in Estimating Gene and Gene Product Similarity

    SciTech Connect

    Sanfilippo, Antonio P.; Posse, Christian; Gopalan, Banu; Tratz, Stephen C.; Gregory, Michelle L.

    2006-06-08

    With the rising influence of the Gene On-tology, new approaches have emerged where the similarity between genes or gene products is obtained by comparing Gene Ontology code annotations associ-ated with them. So far, these approaches have solely relied on the knowledge en-coded in the Gene Ontology and the gene annotations associated with the Gene On-tology database. The goal of this paper is to demonstrate that improvements to these approaches can be obtained by integrating textual evidence extracted from relevant biomedical literature.

  10. Reconsidering the Rhizome: A Textual Analysis of Web Search Engines as Gatekeepers of the Internet

    NASA Astrophysics Data System (ADS)

    Hess, A.

    Critical theorists have often drawn from Deleuze and Guattari's notion of the rhizome when discussing the potential of the Internet. While the Internet may structurally appear as a rhizome, its day-to-day usage by millions via search engines precludes experiencing the random interconnectedness and potential democratizing function. Through a textual analysis of four search engines, I argue that Web searching has grown hierarchies, or "trees," that organize data in tracts of knowledge and place users in marketing niches rather than assist in the development of new knowledge.

  11. Analyzing Cultural Usability of Mobile Keypad and Displays for Textual Communication in Internationalization and Localization Perspectives

    NASA Astrophysics Data System (ADS)

    Orngreen, Rikke; Katre, Dinesh; Sandeep, Mulagapati

    The aim of this paper is to identify the cultural usability aspects that need to be considered while internationalizing or localizing the interaction design of mobile keypads and displays for textual communication. The analysis is based primarily on heuristics tests, where: Hindi, Arabic and Danish mobile phones are evaluated based on assumptions of user needs, and in comparison to English. We have also referred the existing research on Chinese mobile phones to further complement our work. The study provides an insight into the much needed local-language centred approach in contrast with the current English centred approach of existing mobile keypad designs and display of text.

  12. ESTABLISHING DERIVED TEXTUAL CONTROL IN ACTIVITY SCHEDULES WITH CHILDREN WITH AUTISM

    PubMed Central

    Miguel, Caio F; Yang, Heejean G; Finn, Heather E; Ahearn, William H

    2009-01-01

    Activity schedules are often used to facilitate task engagement and transition for children with autism. This study evaluated whether conditional discrimination training would serve to transfer the control from activity-schedule pictures to printed words (i.e., derived textual control). Two preschoolers with autism were taught to select pictures and printed words given their dictated names. Following training, participants could respond to printed words by completing the depicted task, match printed words to pictures, and read printed words without explicit training (i.e., emergent relations). PMID:20190932

  13. [Textual research of Hou ke mi yao (Secret Key of Laryngology)].

    PubMed

    Zhang, Liang-Liang

    2013-05-01

    Hou ke mi yao (Secret Key of Laryngology) was one of the most popular books of throat department in the Qing Dynasty. Because of the inscription "Xiyuan Zheng of ancient She as the author, Xu Zuo-ting of Lequan revised and enlarged", this book was generally regarded as the important work of Xin'an Zheng's family of throat department. However, after the textual research, Hou ke mi yao, in fact, was edited on the basis of Zhang Zong-liang's Hou ke zhi zhang (Guide Book for Laryngology) of the Qing Dynasty: with the second volume, "method of processing" deleted, and Wu's "verse of 24 kinds of symptom of throat diseases" (his whole name unknown) and 12 pills added. Thus, the author of Hou ke mi yao was Zhang and Wu instead of Xiyuan Zheng, and the contents reflected the academic thought of Zhang Zong-liang and Wu. According to the record of General Catalogue of the Ancient Literature of Chinese Medicine in China, there were 14 editions of Hou ke mi yao available, however, only 12 editions are extant after the investigation. In addition, there are mistakes of its author, book title and editions included in the Textual Research on Chinese Medical Literature and General Catalogue of the Ancient Literature of Chinese Medicine in China which, therefore, should be corrected. PMID:24060030

  14. Textual and visual content-based anti-phishing: a Bayesian approach.

    PubMed

    Zhang, Haijun; Liu, Gang; Chow, Tommy W S; Liu, Wenyin

    2011-10-01

    A novel framework using a Bayesian approach for content-based phishing web page detection is presented. Our model takes into account textual and visual contents to measure the similarity between the protected web page and suspicious web pages. A text classifier, an image classifier, and an algorithm fusing the results from classifiers are introduced. An outstanding feature of this paper is the exploration of a Bayesian model to estimate the matching threshold. This is required in the classifier for determining the class of the web page and identifying whether the web page is phishing or not. In the text classifier, the naive Bayes rule is used to calculate the probability that a web page is phishing. In the image classifier, the earth mover's distance is employed to measure the visual similarity, and our Bayesian model is designed to determine the threshold. In the data fusion algorithm, the Bayes theory is used to synthesize the classification results from textual and visual content. The effectiveness of our proposed approach was examined in a large-scale dataset collected from real phishing cases. Experimental results demonstrated that the text classifier and the image classifier we designed deliver promising results, the fusion algorithm outperforms either of the individual classifiers, and our model can be adapted to different phishing cases. PMID:21824844

  15. Accuracy of Judgments of Personality Based on Textual Information on Major Life Domains.

    PubMed

    Borkenau, Peter; Mosch, Alice; Tandler, Nancy; Wolf, Annegret

    2016-04-01

    We studied the accuracy of personality impressions relying on textual information on important life domains. Specifically, how is accuracy moderated by the trait being judged, information being provided, judgeability of target persons, and perceptiveness of judges? A sample of 208 students was recruited in groups of four mutual acquaintances who described themselves and each other on a measure of the Five-Factor Model of personality. Moreover, they wrote essays on their hobbies, friends, family, academic studies, and plans for the future and provided self-reports on possible predictors of expressive accuracy. The essays were delivered to 130 strangers who reported their impressions of the personality of the targets and provided self-reports on possible predictors of perceptive accuracy. Accuracy was measured by correlating these impressions with the descriptions of the targets by their acquaintances. The judges used the available information efficiently. Overall, impressions of Openness to Experience were most accurate, but accuracy depended on the information being provided. Several predictors of expressive and perceptive accuracy were identified using Biesanz's (2010) social accuracy model. The results advance our understanding of factors contributing to and moderating the accuracy of personality impressions based on textual information. PMID:25417640

  16. Biomedical imaging modality classification using combined visual features and textual terms.

    PubMed

    Han, Xian-Hua; Chen, Yen-Wei

    2011-01-01

    We describe an approach for the automatic modality classification in medical image retrieval task of the 2010 CLEF cross-language image retrieval campaign (ImageCLEF). This paper is focused on the process of feature extraction from medical images and fuses the different extracted visual features and textual feature for modality classification. To extract visual features from the images, we used histogram descriptor of edge, gray, or color intensity and block-based variation as global features and SIFT histogram as local feature. For textual feature of image representation, the binary histogram of some predefined vocabulary words from image captions is used. Then, we combine the different features using normalized kernel functions for SVM classification. Furthermore, for some easy misclassified modality pairs such as CT and MR or PET and NM modalities, a local classifier is used for distinguishing samples in the pair modality to improve performance. The proposed strategy is evaluated with the provided modality dataset by ImageCLEF 2010. PMID:21912534

  17. Indexing the medical open access literature for textual and content-based visual retrieval.

    PubMed

    Eggel, Ivan; Müller, Henning

    2010-01-01

    Over the past few years an increasing amount of scientific journals have been created in an open access format. Particularly in the medical field the number of openly accessible journals is enormous making a wide body of knowledge available for analysis and retrieval. Part of the trend towards open access publications can be linked to funding bodies such as the NIH1 (National Institutes of Health) and the Swiss National Science Foundation (SNF2) requiring funded projects to make all articles of funded research available publicly. This article describes an approach to make part of the knowledge of open access journals available for retrieval including the textual information but also the images contained in the articles. For this goal all articles of 24 journals related to medical informatics and medical imaging were crawled from the web pages of BioMed Central. Text and images of the PDF (Portable Document Format) files were indexed separately and a web-based retrieval interface allows for searching via keyword queries or by visual similarity queries. Starting point for a visual similarity query can be an image on the local hard disk that is uploaded or any image found via the textual search. Search for similar documents is also possible. PMID:20841890

  18. Content-based retrieval of historical Ottoman documents stored as textual images.

    PubMed

    Saykol, Ediz; Sinop, Ali Kemal; Güdükbay, Ugur; Ulusoy, Ozgür; Cetin, A Enis

    2004-03-01

    There is an accelerating demand to access the visual content of documents stored in historical and cultural archives. Availability of electronic imaging tools and effective image processing techniques makes it feasible to process the multimedia data in large databases. In this paper, a framework for content-based retrieval of historical documents in the Ottoman Empire archives is presented. The documents are stored as textual images, which are compressed by constructing a library of symbols occurring in a document, and the symbols in the original image are then replaced with pointers into the codebook to obtain a compressed representation of the image. The features in wavelet and spatial domain based on angular and distance span of shapes are used to extract the symbols. In order to make content-based retrieval in historical archives, a query is specified as a rectangular region in an input image and the same symbol-extraction process is applied to the query region. The queries are processed on the codebook of documents and the query images are identified in the resulting documents using the pointers in textual images. The querying process does not require decompression of images. The new content-based retrieval framework is also applicable to many other document archives using different scripts. PMID:15376924

  19. Deficits of cognitive restructuring in major depressive disorder: Measured by textual micro-counseling dialogues.

    PubMed

    Jiang, Nengzhi; Yu, Fei; Zhang, Wencai; Zhang, Jianxin

    2016-04-30

    Cognitive restructuring is an important strategy in cognitive behavioral therapy (CBT). The present study aimed to observe cognitive restructuring in major depressive disorder (MDD) patients using textual micro-counseling dialogue situations. A set of textual micro-counseling dialogues was used to trigger cognitive restructuring in 25 MDD patients and 27 healthy adults. The participants read descriptions ("problems") and explanations ("solutions") for psychologically distressing situations. High-, low-, and zero-restructuring solutions were randomly matched to the problems. The participants evaluated the adaptability and emotional valence of the problems and the insightfulness, adaptability, novelty, and emotional valence of the solutions. Insightfulness ratings for high-restructuring solutions were significantly higher relative to those of low-restructuring solutions in healthy adults, while adaptability ratings for low-restructuring solutions were significantly higher relative to those of high-restructuring solutions in MDD patients. Insightfulness ratings for the solutions were significantly predicted by novelty and adaptability in healthy adults and emotional valence in MDD patients. Lower insightfulness in high-restructuring solutions and higher adaptability in low-restructuring solutions in MDD patients may reflect deficits in cognitive control. PMID:27086227

  20. Instantánea del melanoma

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el melanoma; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  1. Instantánea del sarcoma

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el sarcoma; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  2. Instantánea del linfoma

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el linfoma; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  3. Instantánea del mieloma

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el mieloma; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  4. Text + Book = Textbook? Development of a Conceptual Framework for Non-Textual Elements in Middle School Mathematics Textbooks

    ERIC Educational Resources Information Center

    Kim, Rae Young

    2009-01-01

    This study is an initial analytic attempt to iteratively develop a conceptual framework informed by both theoretical and practical perspectives that may be used to analyze non-textual elements in mathematics textbooks. Despite the importance of visual representations in teaching and learning, little effort has been made to specify in any…

  5. Pretext, Context, Subtext: Textual Power in the Writing of Langston Hughes, Richard Wright, and Martin Luther King, Jr.

    ERIC Educational Resources Information Center

    Bogumil, Mary L.; Molino, Michael R.

    1990-01-01

    Studies verbal pretexts, social subtexts, and interpretive contexts of works by Langston Hughes, Richard Wright, and Martin Luther King, Jr. Notes that cultural repression is propagated (and dispelled) in part through the power of language. Notes that these texts are relevant for teaching textual power in hopes of affecting social change. (RS)

  6. Effects of Textual Enhancement and Topic Familiarity on Korean EFL Students' Reading Comprehension and Learning of Passive Form

    ERIC Educational Resources Information Center

    Lee, Sang-Ki

    2007-01-01

    This quasi-experimental study attempts to incorporate grammatical elements into meaning-focused reading classes by attracting learner attention to form with minimal interruption to meaning comprehension. Two hundred fifty-nine Korean English as a foreign language students underwent four different treatments--involving textual enhancement and topic…

  7. The Impact of Textual Input Enhancement and Explicit Rule Presentation on Iranian Elementary EFL Learners' Intake of Simple Past Tense

    ERIC Educational Resources Information Center

    Nahavandi, Naemeh; Mukundan, Jayakaran

    2013-01-01

    The present study investigated the impact of textual input enhancement and explicit rule presentation on 93 Iranian EFL learners' intake of simple past tense. Three intact general English classes in Tabriz Azad University were randomly assigned to: 1) a control group; 2) a TIE group; and 3) a TIE plus explicit rule presentation group. All…

  8. Translation Competence and Translation Performance: Lexical, Syntactic and Textual Patterns in Student Translations of a Specialized EU Genre

    ERIC Educational Resources Information Center

    Karoly, Adrienn

    2012-01-01

    This paper reports the findings of a study aiming to reveal the recurring patterns of lexical, syntactic and textual errors in student translations of a specialized EU genre from English into Hungarian. By comparing the student translations to the official translation of the text, this article uncovers the most frequent errors that students made…

  9. The Generator of the Event Structure Lexicon (GESL): Automatic Annotation of Event Structure for Textual Inference Tasks

    ERIC Educational Resources Information Center

    Im, Seohyun

    2013-01-01

    This dissertation aims to develop the Generator of the Event Structure Lexicon (GESL) which is a tool to automate annotating the event structure of verbs in text to support textual inference tasks related to lexically entailed subevents. The output of the GESL is the Event Structure Lexicon (ESL), which is a lexicon of verbs in text which includes

  10. The Generator of the Event Structure Lexicon (GESL): Automatic Annotation of Event Structure for Textual Inference Tasks

    ERIC Educational Resources Information Center

    Im, Seohyun

    2013-01-01

    This dissertation aims to develop the Generator of the Event Structure Lexicon (GESL) which is a tool to automate annotating the event structure of verbs in text to support textual inference tasks related to lexically entailed subevents. The output of the GESL is the Event Structure Lexicon (ESL), which is a lexicon of verbs in text which includes…

  11. [Textual research of scabies in the Warring States and Qin-Han Dynasties].

    PubMed

    Luo, Baozhen

    2014-09-01

    Scabies, a kind of skin disease frequently seen in the period of Warring States and Qin-Han Dynasties. By investigating the epidemic condition, disease title, recognition on the disease and the prevention and its treatment through the textual documents, unearthed texts, and dictionaries of this period, it can be seen that "scabies" refers to the itching and corrugation of skin. It was also called "jia" (scar) and belonged to the "dry itching"disease. At that time, people also knew the seasonal, and geographical rules of its incidence and its pathogenic agent, the scabies parasite (sacoptic mite). Treatments included hot compress, rubbing, bathing, and internal medications, mostly inherited in later generations. PMID:25579210

  12. Figurative language and reading comprehension in American deaf and hard-of-hearing children: textual interactions.

    PubMed

    Rittenhouse, R K; Stearns, K

    1990-12-01

    The limited evidence on figurative language in deaf children, as well as 'professional intuitions', has led those who teach them to conclude that reading comprehension will be significantly complicated by figurative language. However, there are disagreements among practitioners as to how best to manage figurative language when it appears in text. Generally, some sort of textual modification is made, although those for and against 'simplified texts' are split on this issue. Those who favour them suggest either that complex vocabulary and syntax be reconstructed or that they be gradually introduced. However, reformulations are seldom standard nor are the figurative tropes such as metaphor, simile, personification etc. systematically introduced. Those against simplified texts argue that the problem of figurative language control is not one of linguistic complexity, but one of cognitive processing: deaf children can grasp inferred or indirect meaning so long as the referential domain is made clear. Such comprehension comes by way of demonstration, practice and feedback and figurative language need not present a special problem. In this present study, 14 deaf and hard-of-hearing children and youths who had been randomly assigned to one of two groups were given an original story entitled 'Peaches the Cat' and asked to read it. One group read a literal version of the story and one group read a figurative version in which all textual answers to the question were masked with figurative phraseology. Both groups answered the questions above a chance level and the figurative version did not prove to be more difficult than the literal version. The two groups were comparable on hearing loss and on reading and language ability.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:2095841

  13. Determinación del Continuo No-Estelar en AGNs del Tipo NLS1

    NASA Astrophysics Data System (ADS)

    Oio, G. A.; Vega Neme, L.; Schmidt, E.; Ferreiro, D.

    Narrow Line Seyfert 1 (NLS1) are a subclass of AGN with Seyfert 1 characteristics but without broad prominent lines. We approach the determination of the non-stellar continuum using the spectral synthesis technique. In order to achieve this goal, we chose a sample of 130 NLS1 up to z = 0.1. Using this method we determined: (a) central black holes masses, (b) acretion rates, (c) electronic densities in the narrow line region, and we found some correlations between these parameters. FULL TEXT IN SPANISH

  14. Large Scale Near-Duplicate Celebrity Web Images Retrieval Using Visual and Textual Features

    PubMed Central

    Wang, Cheng; Zhang, Xin; Wang, Hui

    2013-01-01

    Near-duplicate image retrieval is a classical research problem in computer vision toward many applications such as image annotation and content-based image retrieval. On the web, near-duplication is more prevalent in queries for celebrities and historical figures which are of particular interest to the end users. Existing methods such as bag-of-visual-words (BoVW) solve this problem mainly by exploiting purely visual features. To overcome this limitation, this paper proposes a novel text-based data-driven reranking framework, which utilizes textual features and is combined with state-of-art BoVW schemes. Under this framework, the input of the retrieval procedure is still only a query image. To verify the proposed approach, a dataset of 2 million images of 1089 different celebrities together with their accompanying texts is constructed. In addition, we comprehensively analyze the different categories of near duplication observed in our constructed dataset. Experimental results on this dataset show that the proposed framework can achieve higher mean average precision (mAP) with an improvement of 21% on average in comparison with the approaches based only on visual features, while does not notably prolong the retrieval time. PMID:24163631

  15. "A hint of it, with initials": adultery, textuality and publicity in Jane Austen's Lady Susan.

    PubMed

    Russell, Gillian

    2010-01-01

    In spite of Jane Austen's professed “eye” for an adulteress, comparatively little attention has been paid to adultery and divorce as themes and contexts of her fiction. Her unpublished epistolary novel Lady Susan has a distinctive status in Austen's oeuvre, recognized as being exemplary of her “style” and yet atypical of her later achievement. A neglected context for the novel is the extensive reporting of adultery trials in contemporary print culture and the moral panic concerning adultery in the 1780s and 1790s, focusing initially on the adulteress as the brazen woman of fashion and later as a figure of sentimentalized abjection. A particularly notorious case, that involving Lady Henrietta Grosvenor and George III's brother, the Duke of Cumberland, is directly alluded to in Lady Susan. The textual strategies of adultery trial literature, particularly its emphasis on indirection through the use of detail or “hint”, had a long-term influence on the development of Austen's fiction and her positioning of herself as a professional writer after the 1790s. PMID:21275195

  16. Mapping annotations with textual evidence using an scLDA model

    PubMed Central

    Jin, Bo; Chen, Vicky; Chen, Lujia; Lu, Xinghua

    2011-01-01

    Most of the knowledge regarding genes and proteins is stored in biomedical literature as free text. Extracting information from complex biomedical texts demands techniques capable of inferring biological concepts from local text regions and mapping them to controlled vocabularies. To this end, we present a sentence-based correspondence latent Dirichlet allocation (scLDA) model which, when trained with a corpus of PubMed documents with known GO annotations, performs the following tasks: 1) learning major biological concepts from the corpus, 2) inferring the biological concepts existing within text regions (sentences), and 3) identifying the text regions in a document that provides evidence for the observed annotations. When applied to new gene-related documents, a trained scLDA model is capable of predicting GO annotations and identifying text regions as textual evidence supporting the predicted annotations. This study uses GO annotation data as a testbed; the approach can be generalized to other annotated data, such as MeSH and MEDLINE documents. PMID:22195141

  17. Large scale near-duplicate celebrity web images retrieval using visual and textual features.

    PubMed

    Qiao, Fengcai; Wang, Cheng; Zhang, Xin; Wang, Hui

    2013-01-01

    Near-duplicate image retrieval is a classical research problem in computer vision toward many applications such as image annotation and content-based image retrieval. On the web, near-duplication is more prevalent in queries for celebrities and historical figures which are of particular interest to the end users. Existing methods such as bag-of-visual-words (BoVW) solve this problem mainly by exploiting purely visual features. To overcome this limitation, this paper proposes a novel text-based data-driven reranking framework, which utilizes textual features and is combined with state-of-art BoVW schemes. Under this framework, the input of the retrieval procedure is still only a query image. To verify the proposed approach, a dataset of 2 million images of 1089 different celebrities together with their accompanying texts is constructed. In addition, we comprehensively analyze the different categories of near duplication observed in our constructed dataset. Experimental results on this dataset show that the proposed framework can achieve higher mean average precision (mAP) with an improvement of 21% on average in comparison with the approaches based only on visual features, while does not notably prolong the retrieval time. PMID:24163631

  18. Strains in experimental social psychology: a textual anaylsis of the development of experimentation in social psychology.

    PubMed

    Stam, H J; Radtke, H L; Lubek, I

    2000-01-01

    A textual analysis of post-World War II social psychology methodology manuals and handbook chapters on "methods" indicates that the introduction of the experimental method was enforced and gradually strengthened through the use of scientific rhetoric and the minimization of alternative research strategies. As a consequence, by the 1960s experimentation had become such an established identifying feature of psychological social psychology that the acceptability of ideas in the field came to depend largely on the ability of authors to couch them in the language of the experiment. Text writers continually shored up the defenses of scientific legitimacy and denigrated all other types of argument. We explore three sources of tension or strains evident as contradictions in these texts: (1) between a rational experimenter's carefully following prescribed, logic-generated scientific practices and the investigator's artfully or intuitively designing research; (2) between social psychologists' missionary activities of proselytizing the experiment as the primary research method and social psychologists' apologies and insecurities expressed about using experiments; and (3) between the treatment of participants as docile and submissive versus portraying them as underhanded and damaging to the outcome of the research. In addition, we briefly reexamine the strain (4) between sober scientific experimentation and a playful "fun and games" approach to experimentation (Lubek & Stam, 1995). PMID:11054732

  19. Aligning ontologies and integrating textual evidence for pathway analysis of microarray data

    SciTech Connect

    Gopalan, Banu; Posse, Christian; Sanfilippo, Antonio P.; Stenzel-Poore, Mary; Stevens, S.L.; Castano, Jose; Beagley, Nathaniel; Riensche, Roderick M.; Baddeley, Bob; Simon, R.P.; Pustejovsky, James

    2006-10-08

    Expression arrays are introducing a paradigmatic change in biology by shifting experimental approaches from single gene studies to genome-level analysis, monitoring the ex-pression levels of several thousands of genes in parallel. The massive amounts of data obtained from the microarray data needs to be integrated and interpreted to infer biological meaning within the context of information-rich pathways. In this paper, we present a methodology that integrates textual information with annotations from cross-referenced ontolo-gies to map genes to pathways in a semi-automated way. We illustrate this approach and compare it favorably to other tools by analyzing the gene expression changes underlying the biological phenomena related to stroke. Stroke is the third leading cause of death and a major disabler in the United States. Through years of study, researchers have amassed a significant knowledge base about stroke, and this knowledge, coupled with new technologies, is providing a wealth of new scientific opportunities. The potential for neu-roprotective stroke therapy is enormous. However, the roles of neurogenesis, angiogenesis, and other proliferative re-sponses in the recovery process following ischemia and the molecular mechanisms that lead to these processes still need to be uncovered. Improved annotation of genomic and pro-teomic data, including annotation of pathways in which genes and proteins are involved, is required to facilitate their interpretation and clinical application. While our approach is not aimed at replacing existing curated pathway databases, it reveals multiple hidden relationships that are not evident with the way these databases analyze functional groupings of genes from the Gene Ontology.

  20. Instantánea del cáncer colorrectal

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer colorrectal; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  1. Instantánea del sarcoma de Kaposi

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el sarcoma de Kaposi; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  2. Computers in the Teaching of English as a Foreign Language: Access to the Diversity of Textual Genres and Language Skills

    NASA Astrophysics Data System (ADS)

    Dos Santos, Roberto-Márcio; Sobrinho, Jerônimo Coura

    In the area of language teaching both language skills and textual genres can be worked with simultaneously (thus responding to the Brazilian Curricular Parameters and to the trends in contemporary education, which emphasize contextualized teaching) by means of computers. Computers can make the teaching process dynamic and rich, since they enable the access to the foreign language through virtual environments, which creates a larger number of learning contexts, with all their specific vocabulary and linguistic features in real communication. This study focuses on possible applications of this kind of approach. The computer online is a resource of diverse textual genres and can be an important tool in the language classroom as well as an access to authentic material produced in contextualized practice close to real-life communication. On the other hand, all these materials must be appropriately used without ever worshipping the technology as if it were a miraculous solution. After all, the professional pedagogic skills of the teacher should never be forgotten or taken for granted. In this study, a series of interviews with teachers was carried out - both with Brazilian teachers of the public sector (basic education) and language institutes (private English courses) as well as teacher trainers (university professors), in order to verify if the teachers were prepared to work with informatics in teaching practices, and check the professionals’ views on the subject. The ideas of Maingueneau and Marcuschi about textual genres are a theoretical base in this work, besides the concept of cognitive economy. The text and its typology are focused here as the basic material for teaching English, through digital technologies and hypermedia. The study is also based on Sharma and Barrett’s notion of blended learning as a balanced combination of technological resources and traditional practices in the classroom. Thus, this is an attempt to investigate the relevance of information and communication technologies in the education and professional practice of English teachers in Brazil in the context of the 21st century.

  3. The social organization of representations of history: the textual accomplishment of coming to terms with the past.

    PubMed

    Tileagă, Cristian

    2009-06-01

    This paper is concerned with the social organization of collective memory and representations of history in the context of how post-communist democracies reckon with former regimes. It specifically centres on the textual accomplishment of coming to terms with the past in the 'Tismăneanu Report' condemning Communism in Romania. The focus is on how the Report displays and shapes the ideological contours of coming to terms with the past around a particular 'social representation' of history. Several constitutive features of the Report that facilitate bringing off a particular 'representation of history' are identified: (a) the construction of a practical framework for the inquiry as a matter of public concern and attention; (b) the production of 'Communism' as an empirical category with uniquely bound features; and (c) the structuring of time by bringing together a political agenda and national identity. The present argument tries to place representations of history (and coming to terms with the past) as something in need of constitution rather than simply relied on. It is suggested that a conception of coming to terms with the past as a textual accomplishment may lead to a fuller appreciation of the structure, function and salience of representations of history as integral part of moral/political/legal courses of action. PMID:18817593

  4. Instantánea de los cánceres de cerebro y del sistema nervioso central

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre los cánceres de cerebro y del sistema nervioso central; así como ejemplos de actividades del NCI y adelantos en la investigación de estos tipos de cáncer.

  5. Evaluating the Effects of Massed and Distributed Practice on Acquisition and Maintenance of Tacts and Textual Behavior with Typically Developing Children

    ERIC Educational Resources Information Center

    Haq, Shaji S.; Kodak, Tiffany

    2015-01-01

    This study evaluated the effects of massed and distributed practice on the acquisition of tacts and textual behavior in typically developing children. We compared the effects of massed practice (i.e., consolidating all practice opportunities during the week into a single session) and distributed practice (i.e., distributing all practice…

  6. Donner de la voix et de la plume: Analyse textuelle et creativite (Giving Voice and Written Form: Textual Analysis and Creativity).

    ERIC Educational Resources Information Center

    Kassis-Bocquillon, Paule

    1990-01-01

    A method and activities for approaching textual analysis with language students and making it something other than an academic exercise is discussed and illustrated. The technique uses reading by a variety of methods, oral and quiet, for producing insight into the text. (MSE)

  7. Shifting Norms and Expectations for Medical School Leaders: A Textual Analysis of Career Advertisements 2000-2004 cf. 2010-2014

    ERIC Educational Resources Information Center

    Gorsky, Diane; MacLeod, Anna

    2016-01-01

    Leadership norms and expectations are continually evolving in higher education. Medical education is no exception to that trend, but shifts over time are intangible and difficult to measure. To explore emerging changes, the authors conducted a textual analysis of published career advertisements from 2000-2004 and 2010-2014. While a number of

  8. Chemical Understanding and Graphing Skills in an Honors Case-Based Computerized Chemistry Laboratory Environment: The Value of Bidirectional Visual and Textual Representations

    ERIC Educational Resources Information Center

    Dori, Yehudit J.; Sasson, Irit

    2008-01-01

    The case-based computerized laboratory (CCL) is a chemistry learning environment that integrates computerized experiments with emphasis on scientific inquiry and comprehension of case studies. The research objective was to investigate chemical understanding and graphing skills of high school honors students via bidirectional visual and textual

  9. "I Have No Time to Find out Where the Sentences Came from; I Just Rebuild Them": A Biochemistry Professor Eliminating Novices' Textual Borrowing

    ERIC Educational Resources Information Center

    Li, Yongyan

    2012-01-01

    English as an Additional Language (EAL) students' textual borrowing in disciplinary writing has attracted wide research interest in recent years. However, much of the research was conducted in the regular curriculum setting while the relevance of the issue in a writing-for-publication context has largely been overlooked. In particular,…

  10. Shifting Norms and Expectations for Medical School Leaders: A Textual Analysis of Career Advertisements 2000-2004 cf. 2010-2014

    ERIC Educational Resources Information Center

    Gorsky, Diane; MacLeod, Anna

    2016-01-01

    Leadership norms and expectations are continually evolving in higher education. Medical education is no exception to that trend, but shifts over time are intangible and difficult to measure. To explore emerging changes, the authors conducted a textual analysis of published career advertisements from 2000-2004 and 2010-2014. While a number of…

  11. Richness, Redundancy or Relational Salience? A Comparison of the Effect of Textual and Aural Feedback Modes on Knowledge Elaboration in Higher Education Students' Work

    ERIC Educational Resources Information Center

    Gleaves, Alan; Walker, Caroline

    2013-01-01

    This study examines the effects of formative assessment feedback commentaries utilizing textual and aural media on the quality of knowledge elaboration within the written work of a sample of 104 higher education students. A randomized, mixed methodological approach was adopted that examined changes within the students' work over a period of one…

  12. Evaluating the Effects of Massed and Distributed Practice on Acquisition and Maintenance of Tacts and Textual Behavior with Typically Developing Children

    ERIC Educational Resources Information Center

    Haq, Shaji S.; Kodak, Tiffany

    2015-01-01

    This study evaluated the effects of massed and distributed practice on the acquisition of tacts and textual behavior in typically developing children. We compared the effects of massed practice (i.e., consolidating all practice opportunities during the week into a single session) and distributed practice (i.e., distributing all practice

  13. Combining Hierarchical and Associative Gene Ontology Relations with Textual Evidence in Estimating Gene and Gene Product Similarity

    SciTech Connect

    Sanfilippo, Antonio P.; Posse, Christian; Gopalan, Banu; Riensche, Roderick M.; Beagley, Nathaniel; Baddeley, Bob L.; Tratz, Stephen C.; Gregory, Michelle L.

    2007-03-01

    Gene and gene product similarity is a fundamental diagnostic measure in analyzing biological data and constructing predictive models for functional genomics. With the rising influence of the Gene Ontology, two complementary approaches have emerged where the similarity between two genes or gene products is obtained by comparing Gene Ontology (GO) annotations associated with the genes or gene products. One approach captures GO-based similarity in terms of hierarchical relations within each gene subontology. The other approach identifies GO-based similarity in terms of associative relations across the three gene subontologies. We propose a novel methodology where the two approaches can be merged with ensuing benefits in coverage and accuracy, and demonstrate that further improvements can be obtained by integrating textual evidence extracted from relevant biomedical literature.

  14. Instantánea del cáncer de riñón

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de riñón; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  15. Instantánea del cáncer de vejiga

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de vejiga; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  16. Instantánea del cáncer de estómago

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de estómago; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  17. Instantánea del cáncer de ovario

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de ovario; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  18. Instantánea del cáncer de tiroides

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de tiroides; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  19. Instantánea del cáncer de esófago

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de esófago; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  20. Instantánea del cáncer de endometrio

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de endometrio; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  1. Instantánea del cáncer de cuello uterino

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de cuello uterino; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  2. Instantánea del cáncer de pulmón

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de pulmón; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  3. Instantánea del cáncer de páncreas

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de páncreas; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  4. Instantánea del cáncer de seno (mama)

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de seno (mama); así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  5. Instantánea del cáncer de próstata

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de próstata; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  6. Medicin de los parmetros cosmolgicos q0, ?M, y ??, usando supernovas de Tipo Ia distantes

    NASA Astrophysics Data System (ADS)

    Clocchiatti, A.; High-Z Sne Search Team

    Las supernovas de tipo Ia son una herramienta de gran precisin para la medicin de distancias de inters cosmolgico. Los mtodos recientes de calibracin de su luminosidad intrnseca, que hacen uso de la forma de las curvas de luz en varios colores y permiten diferenciar entre supernovas distantes, intrnsecamente dbiles, u oscurecidas por extincin, reducen la dispersin del mtodo que las asume de magnitud absoluta constante de 0.50 mag a 0.15 mag, e incrementa el valor de la constante de Hubble de ~55 km s-1 Mpc-1, a 65 km s-1 Mpc-1. A partir de la calibracin de las supernovas cercanas, con redshifts menores que 0.1, se pueden obtener distancias precisas a supernovas que explotan a alto redshift. Hemos aplicado estos mtodos a 16 supernovas con 0.16 < Z < 0.97, encontrando que sus distancias son, en promedio, entre 10% y 13% (dependiendo del mtodo empleado) mayores que las que uno esperara en un universo con poca masa (? = 0.2), sin una constante cosmolgica. Todos los mtodos de ajuste de curvas de luz, y seleccin de subgrupos de la muestra de supernovas observadas, favorecen consistentemente modelos del universo que se expanden eternamente y que tienen una constante cosmolgica positiva (?? > 0), y una aceleracin de la expansin al presente (q0 < 0). Hay distintas fuentes de posibles errores sistemticos que merecen ser analizadas, entre ellas: evolucin de la metalicidad y estrellas progenitoras, extincin, bias en la eleccin de la muestra, amplificacin por gravitational lensing, y contaminacin de la muestra. Ninguno de estos efectos alcanza para reconciliar los datos con ?? = 0, o q0 > 0.

  7. Evaluating the effects of massed and distributed practice on acquisition and maintenance of tacts and textual behavior with typically developing children.

    PubMed

    Haq, Shaji S; Kodak, Tiffany

    2015-01-01

    This study evaluated the effects of massed and distributed practice on the acquisition of tacts and textual behavior in typically developing children. We compared the effects of massed practice (i.e., consolidating all practice opportunities during the week into a single session) and distributed practice (i.e., distributing all practice opportunities across 4 sessions during the week) on the acquisition of textual behavior in English, tacting pictures of common nouns in Spanish, and textual behavior in Spanish using an adapted alternating treatments design embedded within a multiple probe design. We also examined correct responding during probes that (a) excluded prompts and reinforcement and (b) occurred 48 hr after training each week. The results indicated that distributed practice was the more efficient training format. Maintenance data collected up to 4 weeks after training also indicated that the participants consistently displayed higher levels of correct responding to targets that had been trained in distributed format. We discuss implications for practice and potential areas for future research. PMID:25376717

  8. Web-Based Textual Analysis of Free-Text Patient Experience Comments From a Survey in Primary Care

    PubMed Central

    Davey, Antoinette; Elliott, Marc N; Roberts, Martin; Roland, Martin; Brown, Finlay; Burt, Jenni; Boiko, Olga; Campbell, John

    2015-01-01

    Background Open-ended questions eliciting free-text comments have been widely adopted in surveys of patient experience. Analysis of free text comments can provide deeper or new insight, identify areas for action, and initiate further investigation. Also, they may be a promising way to progress from documentation of patient experience to achieving quality improvement. The usual methods of analyzing free-text comments are known to be time and resource intensive. To efficiently deal with a large amount of free-text, new methods of rapidly summarizing and characterizing the text are being explored. Objective The aim of this study was to investigate the feasibility of using freely available Web-based text processing tools (text clouds, distinctive word extraction, key words in context) for extracting useful information from large amounts of free-text commentary about patient experience, as an alternative to more resource intensive analytic methods. Methods We collected free-text responses to a broad, open-ended question on patients experience of primary care in a cross-sectional postal survey of patients recently consulting doctors in 25 English general practices. We encoded the responses to text files which were then uploaded to three Web-based textual processing tools. The tools we used were two text cloud creators: TagCrowd for unigrams, and Many Eyes for bigrams; and Voyant Tools, a Web-based reading tool that can extract distinctive words and perform Keyword in Context (KWIC) analysis. The association of patients experience scores with the occurrence of certain words was tested with logistic regression analysis. KWIC analysis was also performed to gain insight into the use of a significant word. Results In total, 3426 free-text responses were received from 7721 patients (comment rate: 44.4%). The five most frequent words in the patients comments were doctor, appointment, surgery, practice, and time. The three most frequent two-word combinations were reception staff, excellent service, and two weeks. The regression analysis showed that the occurrence of the word excellent in the comments was significantly associated with a better patient experience (OR=1.96, 95%CI=1.63-2.34), while rude was significantly associated with a worse experience (OR=0.53, 95%CI=0.46-0.60). The KWIC results revealed that 49 of the 78 (63%) occurrences of the word rude in the comments were related to receptionists and 17(22%) were related to doctors. Conclusions Web-based text processing tools can extract useful information from free-text comments and the output may serve as a springboard for further investigation. Text clouds, distinctive words extraction and KWIC analysis show promise in quick evaluation of unstructured patient feedback. The results are easily understandable, but may require further probing such as KWIC analysis to establish the context. Future research should explore whether more sophisticated methods of textual analysis (eg, sentiment analysis, natural language processing) could add additional levels of understanding. PMID:25947632

  9. Exploring the Degree of Concordance of Coded and Textual Data in Answering Clinical Queries from a Clinical Data Repository

    PubMed Central

    Stein, H. David; Nadkarni, Prakash; Erdos, Joseph; Miller, Perry L.

    2000-01-01

    Objective: To query a clinical data repository (CDR) for answers to clinical questions to determine whether different types of fields (coded and free text) would yield confirmatory, complementary, or conflicting information and to discuss the issues involved in producing the discrepancies between the fields. Methods: The appropriate data fields in a subset of a CDR (5,135 patient records) were searched for the answers to three questions related to surgical procedures. Each search included at least one coded data field and at least one free-text field. The identified free-text records were then searched manually to ensure correct interpretation. The fields were then compared to determine whether they agreed with each other, were supportive of each other, contained no entry (absence of data), or were contradictory. Results: The degree of concordance varied greatly according to the field and the question asked. Some fields were not granular enough to answer the question. The free-text fields often gave an answer that was not definitive. Absence of data was most logically interpreted in some cases as lack of completion of data and in others as a negative answer. Even with a question as specific as which side a hernia was on, contradictory data were found in 5 to 8 percent of the records. Conclusions: Using the data in the CDR to answer clinical questions can yield significantly disparate results depending on the question and which data fields are searched. A database cannot just be queried in automated fashion and the results reported. Both coded and textual fields must be searched to obtain the fullest assessment. This can be expected to result in information that may be confirmatory, complementary, or conflicting. To yield the most accurate information possible, final answers to questions require human judgment and may require the gathering of additional information. PMID:10641962

  10. Teaching Generative Reading Via Recombination of Minimal Textual Units: A Legacy of Verbal Behavior to Children in Brazil

    PubMed Central

    de Souza, Deisy G.; de Rose, Julio C.; Faleiros, Thais C.; Bortoloti, Renato; Hanna, Elenice Seixas; McIlvane, William J.

    2009-01-01

    This paper reports results of two studies that sought to teach generative reading skills to a large group of Brazilian children who were exhibiting protracted failure in school. Inspired by Skinner’s analysis of verbal relations and minimal verbal units, the methodology took advantage of certain characteristics of Portuguese. Many words in this language are comprised of two-letter syllabic units (e.g., BO+LA= ball, CA+BO= handle, LA+TA= can) that can be recombined to form new words (e.g., BOCA= mouth, BOTA= boot), thus establishing a route to generative reading via recombinative generalization. Such syllabic units were incorporated within curricular framework that used matching-to-sample and learning by exclusion methods to teach matching relations involving pictures, printed and spoken words, and printed and spoken syllables. Study 1 was conducted within a university-based learning center that maintained certain aspects of laboratory conditions. It showed that teaching textual relations between dictated and printed syllables could control procedurally the inter- and intra-participant variability observed in past studies that lacked this feature -resulting in virtually universally positive teaching outcomes. Study 2 was conducted in a public school programs that applied the same basic training methodology. Positive training outcomes in an experimental group were approximately 3–5 times greater than that in a placebo control group. Together, these studies illustrate that the functional analysis in Verbal Behavior is having a direct impact in educational science in Brazil. It has led to procedures that can be effectively translated from the laboratory to the community via delivery systems that can be implemented in the developing world. PMID:19960112

  11. The Structure of Na 5Ti(PO 4) 3

    NASA Astrophysics Data System (ADS)

    Krimi, S.; Mansouri, I.; El Jazouli, A.; Chaminade, J. P.; Gravereau, P.; Le Flem, G.

    1993-08-01

    The sodium titanium phosphate Na 5Ti(PO 4) 3 crystallizes in the trigonal space group R32 ( a = 9.0607(2) Å, c = 21.734(1) Å, V = 1545.3 Å 3, dm = 2.84(2), dc = 2.89 Mg · m -3, Z = 6). R = 0.022 and Rw = 0.023 for 831 reflections. The structure belongs to the Nasicon-type family and is characterized by a 2-2 titanium-sodium ordering along the c axis. The four crystallographically independent sodium atoms show coordination numbers 6 and 8. The cell parameters and the cationic distribution are consistent with the rules governing the structural evolution of such types of material.

  12. On textual and contextual position of the ophthalmological treatise of bodhisattva nāgārjuna.

    PubMed

    Kim, Seongsu; Kang, Sungyong

    2013-04-01

    Medical knowledge in India began to be introduced to China in earliest from the Later Han Dynasty period to the times of Wei-Qin and South & North Dynasties. This is proved by many Buddhist medical books appeared in those days. Of the contents of Indian medicine, the theory of four major elements affected Chinese medicine more than did the theory of body fluids. Based on the theory of four major elements that was began to be introduced in Fú shuō fú yī jīng, an attempt to establish a new medical system was made in Zhŏu hòu băi yīfāng written by Táo Hóng-jĭng and Sūn Sī-miăo who tried to develop etiology further but could not achieve any great outcomes. Unlike the foregoing situation, Indian medicine aroused a large echo in China in the field of ophthalmology with ophthalmological knowledge mentioned in Suśrutasa hitā and 'Jīnzhēn-shù'(cataract couching) introduced as a surgical treatment of cataract. The Suśrutasa hitā which is one of the three major texts of Indian medicine contains additional information on surgical operations not introduced in the Carakasa hitā. The technique of cataract surgery was particularly popular in the Tang and Song dynasty periods in China under the name Lóng shù pú sà yăn lùn(The Ophthalmological Treatise of Bodhisattva Nāgārjuna) or Lóng shù lùn and was even designated as a subject to educate medical officers. While the original text of Lóng shù pú sà yăn lùn was not handed down, the first testimony that show the trace of the introduction of this text into China was the Tiān zhú jīng lùn yăn mentioned in Wài tái mì yào(Arcane Essential from the Imperial Library) written by Wang Tao. Long shàng dào ren who was mentioned as the compiler of the book is assumed to be Lóng shù. Although Tiān zhú jīng lùn yăn introduced anatomical knowledge about the eyeball that could have not been in the traditional Chinese medicine, this book has only limited quantity of information in this regard. Thereafter, Tài píng shèng huì fāng (Holy Prescriptions for Universal Relief) compiled by a national agency at the beginning of the Song Dynasty period introduced Lóng shù pú sà yăn lùn without clear indication of the reference. Contemporary with this book, many ophthalmological books such as Mì chuán yăn kē lóng mù lùn(Longmu's Ophthalmology Secretly Handed Down) were published. As Chinese culture was spreading out into surrounding countries, medical knowledge was also introduced to Korean peninsula and Japan. The ophthalmological knowledge contained in Lóng shù pú sà yăn lùn was also reflected and some parts of it were introduced in I shin bō in Japan. Based on the policy decision of King Sejong, the fourth king of Joseon Dynasty, large scaled promoting projects of medical knowledge was established. It is notable that the Ui bang ryu chwi compiled as a result of the synthesis of the medical treatises available at that time initiated by King Sejong contained a considerable part of Lóng shù pú sà yăn lùn in reedited form that had already passed into oblivion in China. The intellectuals in Joseon Dynasty who participated in the compilation of Ui bang ryu chwi not only indicated that Lóng shù pú sà yăn lùn was a medical text published in the times of Wei-Qin and South & North Dynasties in China but also clearly indicated the textual reference and left the original text for later generation without modifying the contents. According to the Ui bang ryu chwi, the Lóng shù pú sà yăn lùn indicated that the core causes of eye diseases were heat, winds, and three body fluids(trido a) and contained the analyses of symptoms, related treatments, and several analyses of wrong treatments. In addition, Lóng shù pú sà yăn lùn explained diverse eye diseases through more than 30 medical treatments. In particular, this book accurately described golden needle acupuncture for treatment of a Nèi-zhàng understood to be cataract. Therefore, this book is a significant textual record in the history of ophthalmological medicine in East Asia. Along with the golden needle acupuncture which is a method of removing the crystalline lens in which white turbidity occurred by stabbing the eyeball with a needle, traces of Indian medicine that had been already lost in China were clearly indicated in Lóng shù pú sà yăn lùn kept in the Ui bang ryu chwi. In particular, the book indicates that the eyes were directly correlated with the brain and that to treat the internal disorder, treating the brain that lost stability due to heat and bodily wind was indispensable; these are the traces of Indian influence. This textual source demonstrates a case of knowledge exchange in field of medicine with concrete cases of the encounter and clash between the standpoints of understanding human body. PMID:23695753

  13. Textual abuse: Faulkner's Benjy.

    PubMed

    Truchan-Tataryn, Maria

    2005-01-01

    William Faulkner's The Sound and the Fury has become a classic in literary history. Since its publication in 1929, it has sustained critical interest worldwide. Over time, analyses of this work have reflected shifting cultural perspectives of the inscribed human dynamics such as gender, race and sexuality. This paper contends that a similar critical development cannot be detected around the reception of the character of the "idiot," Benjy. Faulknerian scholarship, regardless of its place in time or trend, persists in conflating the dehumanized images of Benjy with the lived experience of disability, thus perpetuating oppressive disability prejudice and limiting the richness of the character's metaphoric potential. Acknowledging this critical lacuna, historicizing and theorizing Benjy's character from a disability perspective could lead to a deeper understanding of human experience. PMID:15877197

  14. Into the (Textual) West

    ERIC Educational Resources Information Center

    Gannon, Susanne

    2009-01-01

    A critical/creative paradigm in contemporary English carries with it an imperative that students should be given opportunities for deep engagement with texts relevant to what matters in their everyday lives. In this paper, I argue that the materiality of everyday life includes the physical and geographic places where we live. When students live in…

  15. Textual Data in Psychiatry

    PubMed Central

    Yang, Suzanne; Mulvey, Edward P.; Falissard, Bruno

    2013-01-01

    Personal meaning in subjective experience is a key element in the treatment of persons with mental disorders. Open-response speech samples would appear to be suitable for studying this type of subjective experience, but there are still important challenges in using language as data. Scientific principles involved in sample size calculation, validity, and reliability may be applicable, by analogy, to data collected in the form of words. We describe a rationale for including computer-assisted techniques as one step of a qualitative analysis procedure that includes manual reading. Clarification of a framework for including language as data in psychiatric research may allow us to more effectively bridge biological and psychometric research with clinical practice, a setting where the patients clinical data are, in large part, conveyed in words. PMID:22850301

  16. Estudio multifrecuencia del medio interestelar cercano a HD 192281

    NASA Astrophysics Data System (ADS)

    Arnal, E. M.; Cappa, C.; Cichowolski, S.; Pineault, S.; St-Louis, N.

    Una de las causas que modifica la estructura y dinámica del medio interestelar es la acción que los vientos de las estrellas de gran masa ejercen sobre el mismo. En este trabajo, mediante el uso de datos interferométricos obtenidos en la banda de radio en la transición de 21-cm del Hidrógeno neutro y de imágenes de la emisión de continuo en las bandas de 408 y 1420 MHz, de imágenes HIRES del satélite IRAS en 60 y 100 micrones, y de observaciones de continuo obtenidas con radiotelescopios de disco simple en 2695, 4850 y 8350 MHz se ha realizado un estudio multifrecuencia de los efectos que los vientos estelares de HD 192281, una estrella de tipo espectral O5 Vn((f))p, han tenido sobre el medio interestelar que rodea a la misma.

  17. Relaciones fundamentales de la población de galaxias de tipo temprano del cúmulo de Antlia

    NASA Astrophysics Data System (ADS)

    Calderón, J. P.; Bassino, L. P.; Cellone, S. A.; Smith Castelli, A. V.; Caso, J. P.

    We present the results of a study of more than 100 early-type galaxies in Antlia Cluster, that span from giant ellipticals to dwarf ellipticals, covering a magnitude range of 11 magnitudes (M_{V_T} = -22 to -11). We perform surface photometry of these galaxies, and their total magnitudes, surface brightnesses and radii are determined on the basis of the Sérsic law fits. Finally, the fundamental relations between them are analyzed. FULL TEXT IN SPANISH

  18. Home-Type Activities at the Day Care Center. (Tipos De Actividades Del Hogar En El Centro De Cuidado Diario.)

    ERIC Educational Resources Information Center

    Aaronson, May; Moberg, Patricia E.

    This paper argues that home activities comprise a valuable unplanned curriculum and that many of these activities can be transferred to the day care center. It is suggested that these activities foster a closer relationship between child and caregiver and bridge the gap between familiar home environment and novel day care setting. Home activities…

  19. Cinemática y masas de agujeros negros en galaxias activas del tipo "Narrow Line Seyfert 1"

    NASA Astrophysics Data System (ADS)

    Oío, G.; Schmidt, E.; Vega Neme, L. R.

    We apply a spectral synthesis method to Narrow Line Seyfert 1 active galax- ies with public spectra available. Our goal will be to obtain the stellar ve- locity dispersions, and then the central black hole masses via the Tremaine relation. We comment several problems we found in fitting this type of objects and the possibility of obtaining masses through the emission lines. FULL TEXT IN SPANISH

  20. NMR Study of the Spin-Peierls transition in TiPO4

    NASA Astrophysics Data System (ADS)

    Stern, Raivo; Heinmaa, Ivo; Joon, Enno; Law, Joseph; Kremer, Reinhard; Glaum, Robert

    2012-02-01

    We investigated the magnetic and structural properties of the quasi-one dimensional 3d^1-quantum chain system TiPO4 (J ˜ 965 K) by NMR measurements. TiPO4 undergoes two magnetostructural phase transitions, one at 111 K and the other at 74 K. Below 74 K, NMR detects two different ^31P signals and the magnetic susceptibility vanishes, while DFT calculations evidence a bond alternation of the TiTi distances within each chain. Thus, the 74 K phase transition is a spin-Peierls transition which evolves from an incommensurate phase existing between 111 K and 74 K.

  1. Qué tipos hay de estudios clínicos

    Cancer.gov

    Información sobre los diversos tipos de estudios clínicos de cáncer, como son los estudios de tratamiento, de prevención, de exámenes selectivos de detección, de cuidados médicos de apoyo y de cuidados paliativos.

  2. Archivo de placas astrométricas del Observatorio de La Plata

    NASA Astrophysics Data System (ADS)

    di Sisto, R.; Orellana, R. B.

    Se ha realizado una base de datos con las placas fotográficas obtenidas con el Astrográfico del Observatorio de La Plata. Se han clasificado un total de 3000 placas obtenidas para asteroides y cometas. El acceso a la base de datos se hará por FTP y la misma contendrá la siguiente información: fecha y tiempo de exposición, coordenadas del centro de placa, tipo de emulsión fotográfica, estado de la placa, objeto fotografiado.

  3. Textual Encounters and Pedagogic Interventions

    ERIC Educational Resources Information Center

    Vicars, Mark

    2009-01-01

    School, typically, is no place to be caught being queer and knowledge about homosexuality for the majority of young lesbian, gay and bisexual people is routinely constructed within communities of practice. In this paper, I draw upon my own and others' literacy practices to show how our identities and readings of texts were framed by being…

  4. Writing Deaf: Textualizing Deaf Literature

    ERIC Educational Resources Information Center

    Harmon, Kristen

    2007-01-01

    In this article, the author discusses why it is difficult to transliterate American Sign Language (ASL) and the visual realities of a deaf individual's life into creative texts written in English. Even on the sentence level, she says, written English resists the unsettling presence of transliteration across modalities. A sign cannot be "said." If…

  5. Textual Encounters and Pedagogic Interventions

    ERIC Educational Resources Information Center

    Vicars, Mark

    2009-01-01

    School, typically, is no place to be caught being queer and knowledge about homosexuality for the majority of young lesbian, gay and bisexual people is routinely constructed within communities of practice. In this paper, I draw upon my own and others' literacy practices to show how our identities and readings of texts were framed by being

  6. Aztec homosexuality: the textual evidence.

    PubMed

    Kimball, G

    1993-01-01

    Male and female homosexuality among the Aztecs during the period immediately prior to the Spanish Conquest has been studied infrequently, even though a Nahuatl document, the Florentine Codex, written shortly after the Spanish Conquest, contains a number of texts on the subject. The Florentine Codex has been translated into English; however, the translators use biased and erroneous translations in the sections of the manuscript which mention homosexuality, and the actual meaning is unavailable to anyone who does not know Nahuatl. This paper is a new translation and an introductory study of the available texts on homosexuality in the Florentine Codex. The attitudes of the Aztecs toward homosexual men and women can be inferred from these texts, and there are tantalizing fragments which given an indication of how homosexuality fit into Aztec society. PMID:8113605

  7. Protótipo do primeiro interferômetro brasileiro - BDA

    NASA Astrophysics Data System (ADS)

    Cecatto, J. R.; Fernandes, F. C. R.; Neri, J. A. C. F.; Bethi, N.; Felipini, N. S.; Madsen, F. R. H.; Andrade, M. C.; Soares, A. C.; Alonso, E. M. B., Sawant, H. S.

    2004-04-01

    A interferometria é uma poderosa ferramenta usada para investigar estruturas espaciais de fontes astrofísicas fornecendo uma riqueza de detalhes inatingível pelas técnicas convencionais de imageamento. Em particular, a interferometria com ondas de rádio abre o horizonte de conhecimento do Universo nesta ampla banda do espectro eletromagnético, que vai de cerca de 20 kHz até centenas de GHz já próximo ao infravermelho, e que está acessível a partir de instrumentos instalados em solo. Neste trabalho, apresentamos o interferômetro designado por Arranjo Decimétrico Brasileiro (BDA). Trata-se do primeiro interferômetro a ser desenvolvido no Brasil e América Latina que já está em operação na fase de protótipo. Apresentamos o desenvolvimento realizado até o momento, o sítio de instalação do instrumento, o protótipo e os principais resultados dos testes de sua operação, as perspectivas futuras e a ciência a ser desenvolvida com o instrumento nas fases II e III. Neste trabalho é dada ênfase ao desenvolvimento, testes de operação e principais resultados do protótipo. É discutida brevemente a ciência que pode ser feita com o instrumento. Tanto os detalhes técnicos quanto os principais parâmetros estimados para o instrumento nas próximas fases de desenvolvimento e o desempenho do protótipo serão publicados em breve.

  8. 41. DISCOVERY, SEARCH, AND COMMUNICATION OF TEXTUAL KNOWLEDGE RESOURCES IN DISTRIBUTED SYSTEMS a. Discovering and Utilizing Knowledge Sources for Metasearch Knowledge Systems

    SciTech Connect

    Zamora, Antonio

    2008-03-18

    Advanced Natural Language Processing Tools for Web Information Retrieval, Content Analysis, and Synthesis. The goal of this SBIR was to implement and evaluate several advanced Natural Language Processing (NLP) tools and techniques to enhance the precision and relevance of search results by analyzing and augmenting search queries and by helping to organize the search output obtained from heterogeneous databases and web pages containing textual information of interest to DOE and the scientific-technical user communities in general. The SBIR investigated 1) the incorporation of spelling checkers in search applications, 2) identification of significant phrases and concepts using a combination of linguistic and statistical techniques, and 3) enhancement of the query interface and search retrieval results through the use of semantic resources, such as thesauri. A search program with a flexible query interface was developed to search reference databases with the objective of enhancing search results from web queries or queries of specialized search systems such as DOE's Information Bridge. The DOE ETDE/INIS Joint Thesaurus was processed to create a searchable database. Term frequencies and term co-occurrences were used to enhance the web information retrieval by providing algorithmically-derived objective criteria to organize relevant documents into clusters containing significant terms. A thesaurus provides an authoritative overview and classification of a field of knowledge. By organizing the results of a search using the thesaurus terminology, the output is more meaningful than when the results are just organized based on the terms that co-occur in the retrieved documents, some of which may not be significant. An attempt was made to take advantage of the hierarchy provided by broader and narrower terms, as well as other field-specific information in the thesauri. The search program uses linguistic morphological routines to find relevant entries regardless of whether terms are stored in singular or plural form. Implementation of additional inflectional morphology processes for verbs can enhance retrieval further, but this has to be balanced by the possibility of broadening the results too much. In addition to the DOE energy thesaurus, other sources of specialized organized knowledge such as the Medical Subject Headings (MeSH), the Unified Medical Language System (UMLS), and Wikipedia were investigated. The supporting role of the NLP thesaurus search program was enhanced by incorporating spelling aid and a part-of-speech tagger to cope with misspellings in the queries and to determine the grammatical roles of the query words and identify nouns for special processing. To improve precision, multiple modes of searching were implemented including Boolean operators, and field-specific searches. Programs to convert a thesaurus or reference file into searchable support files can be deployed easily, and the resulting files are immediately searchable to produce relevance-ranked results with builtin spelling aid, morphological processing, and advanced search logic. Demonstration systems were built for several databases, including the DOE energy thesaurus.

  9. Preguntas y respuestas acerca del Estudio del

    Cancer.gov

    El Estudio del Tamoxifeno y Raloxifeno (STAR, por sus siglas en ingls) es un estudio clnico (un estudio de investigacin conducido con voluntarios) diseado para ver cómo el medicamento raloxifeno (Evista) se compara con el medicamento tamoxifeno (Nolvadex)

  10. Estudio multifrecuencia del medio interestelar cercano a HD 192281

    NASA Astrophysics Data System (ADS)

    Arnal, E. M.; Cappa, C. E.; Cichowolski, S.; Pineault, S.; St-Louis, N.

    Una de las causas que modifica la estructura y dinámica del medio interestelar es la acción que los vientos de las estrellas de gran masa ejercen sobre el mismo. En este trabajo, mediante el uso de datos interferométricos obtenidos en la banda de radio en la transición de λ˜21-cm del hidrógeno neutro y de imágenes de la emisión de continuo en las bandas de 408 y 1420 MHz, de imágenes HIRES del satélite IRAS en 60 y 100μm, y de observaciones de continuo obtenidas con radiotelescopios de disco simple en 2695, 4850 y 8350 MHz se ha realizado un estudio multifrecuencia de los efectos que los vientos estelares de HD 192281, una estrella de tipo espectral O5,Vn((f))p, han tenido sobre el medio interestelar que rodea a la misma.

  11. Hojas informativas del NCI

    Cancer.gov

    La colección de hojas informativas del NCI trata de una variedad de temas relacionados con el cáncer. Las hojas informativas se revisan y ponen al día de acuerdo a las investigaciones más recientes sobre el cáncer.

  12. Estudio del CH interestelar

    NASA Astrophysics Data System (ADS)

    Olano, C.; Lemarchand, G.; Sanz, A. J.; Bava, J. A.

    El objetivo principal de este proyecto consiste en el estudio de la distribución y abundancia del CH en nubes interestelares a través de la observación de las líneas hiperfinas del CH en 3,3 GHz. El CH es una molécula de amplia distribución en el espacio interestelar y una de las pocas especies que han sido observadas tanto con técnicas de radio como ópticas. Desde el punto de vista tecnológico se ha desarrollado un cabezal de receptor que permitirá la realización de observaciones polarimétricas en la frecuencia de 3,3 GHz, con una temperatura del sistema de 60 K y un ancho de banda de 140 MHz, y que será instalado en el foco primario de la antena parabólica del IAR. El cabezal del receptor es capaz de detectar señales polarizadas, separando las componentes de polarización circular derecha e izquierda. Para tal fin el cabezal consta de dos ramas receptoras que amplificarán la señal y la trasladarán a una frecuencia más baja (frecuencia intermedia), permitiendo de esa forma un mejor transporte de la señal a la sala de control para su posterior procesamiento. El receptor además de tener características polarimétricas, podrá ser usado en el continuo y en la línea, utilizando las ventajas observacionales y de procesamiento de señal que actualmente posee el IAR.

  13. Estudo espectral em raios-X duros de fontes do tipo Z com o HEXTE/RXTE

    NASA Astrophysics Data System (ADS)

    D'Amico, F.; Heindl, W. A.; Rothschild, R. E.

    2003-08-01

    Apresentam-se os resultados de um estudo espectral em raios-X de fontes do tipo Z. As fontes do tipo Z são binárias de raios-X de baixa massa (BXBM) com campo magnético intermediário (B~109G). Esta classe de fontes é composta por apenas 6 fontes Galácticas (a saber: ScoX-1, 9, 7, CygX-2, 5 e 0). A nossa análise se concentra na faixa de raios-X duros (E ~ 20keV), até cerca de 200keV, faixa ótima de operação do telescópio "High Energy X-ray Timing Experiment" (HEXTE), um dos três telescópios de raios-X à bordo do Rossi X-ray Timing Explorer (RXTE). Nossa motivação para tal estudo, uma busca de caudas em raios-X duros em fontes do tipo Z, foi o pouco conhecimento sobre a emissão nesta faixa de energia das referidas fontes quando comparadas, por exemplo, as fontes do tipo atoll (também BXBM). Apresentam-se a análise/redução de dados e explicita-se a maneira como o HEXTE mede o ru1do de fundo. Especial atenção é direcionada a este item devido a localização das fontes do tipo Z e também ao problema de contaminação por fontes próximas. Com exceção de ScoX-1, nenhuma cauda em raios-X duros foi encontrada para as outras fontes, a despeito de resultados de detecção dessas caudas em algumas fontes pelo satélite BeppoSAX. As interpretações deste resultado serão apresentadas. Do ponto de vista deste estudo, nós deduzimos que a produção de caudas de raios-X duros em fontes do tipo Z é um processo disparado quando, pelo menos, uma condição é satisfeita: o brilho da componente térmica do espectro precisa estar acima de um certo valor limiar de ~4´1036ergs-1.

  14. PREVENCIÓN DEL VIH/SIDA EN LOS CIRCUITOS DE LEVANTE HSH: UNA ASIGNATURA PENDIENTE.

    PubMed

    Barreda, Victoria; Carballo-Dieguez, Alex; Marone, Rubén; Balán, Iván; Pando, María Ángeles; Avila, María Mercedes

    2010-12-01

    A partir de un relevamiento de tipo etnográfico, se describen lugares de encuentro de HSH en la Ciudad de Buenos Aires y sus prácticas sexuales. El reconocimiento de tales espacios, así como las características que asumen en ellos los encuentros sexuales entre los HSH, plantean obstáculos específicos en la adopción de comportamientos preventivos y, asimismo, generan nuevos desafíos para las actividades de prevención. Se plantean las dificultades y debates conceptuales que la misma categoría presenta, y sus consecuencias en el abordaje preventivo y teórico-metodológico para las ciencias sociales. Además, se proponen nuevos interrogantes acerca de los alcances y las limitaciones del modelo preventivo del VIH/Sida para HSH. PMID:21874154

  15. Spin-Peierls transition in the S=(1)/(2) compound TiPO4 featuring large intrachain coupling

    NASA Astrophysics Data System (ADS)

    Law, J. M.; Hoch, C.; Glaum, R.; Heinmaa, I.; Stern, R.; Kang, J.; Lee, C.; Whangbo, M.-H.; Kremer, R. K.

    2011-05-01

    We investigated the magnetic and structural properties of the quasi-one-dimensional 3d1 quantum chain system TiPO4 (J~ 965 K) by magnetic susceptibility, heat capacity, electron spin resonance, x-ray diffraction, and nuclear magnetic resonance (NMR) measurements, and by density functional theory (DFT) calculations. TiPO4 undergoes two magnetostructural phase transitions, one at 111 K and the other at 74 K. Below 74 K, NMR detects two different P31 signals and the magnetic susceptibility vanishes, while DFT calculations evidence a bond alternation of the Ti-Ti distances within each chain. Thus, the 74 K phase transition is a spin-Peierls transition which evolves from an incommensurate phase existing between 111 and 74 K.

  16. Nevado del Huila, Columbia

    NASA Technical Reports Server (NTRS)

    2007-01-01

    Nevado del Huila Volcano in Colombia is actually a volcanic chain running north to south, capped by a glacier. With peaks ranging in height from 2,600 to 5,780 meters (8,530 to 18,960 feet), Nevado del Huila is a stratovolcano composed of alternating layers of hardened lava, solidified ash, and volcanic rocks. Its first recorded eruption occurred in the mid-sixteenth century. The long-dormant volcano erupted again in mid-April 2007. A few months before the eruption, the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on NASA's Terra satellite captured this image of Nevado del Huila, on February 23, 2007. In this image, the bright white area just east of the central summit is ice. Immediately west of the summit are bare rocks, appearing as blue-gray. West of those rocks, white reappears, but this patch of white results from clouds hovering in the nearby valley. In the east, the colors turn to brown (indicating bare rock) and bright green (indicating vegetation). ASTER photographed Nevado del Huila near the end of a long phase of quietude. On April 17, 2007, local authorities recorded seismic activity associated with rock fracturing on the volcano's central summit, according to the ReliefWeb Website. Activity intensified the following day with an eruption and mudflows, forcing thousands of nearby residents to evacuate. As the Associated Press reported, the eruption caused avalanches and floods that wiped away both houses and bridges. It marked the volcano's first recorded eruption since the Spanish colonized the area five centuries earlier. NASA image created by Jesse Allen, using data provided courtesy of the NASA/GSFC/MITI/ERSDAC/JAROS, and U.S./Japan ASTER Science Team.

  17. Comportamiento del Helio en estrellas químicamente peculiares

    NASA Astrophysics Data System (ADS)

    Malaroda, S. M.; López García, Z.; Leone, F.; Catalano, F.

    Las estrellas químicamente peculiares (CP) se caracterizan por tener deficiencias y sobreabundancias de algunos elementos químicos de hasta 106 veces la abundancia solar. Además presentan variaciones en las líneas espectrales. Se piensa que ello se debe a que los campos magnéticos presentes en este tipo de estrellas son principalmente dipolares, con un eje de simetría diferente del eje de rotación. La distribución de los elementos sobreabundantes y deficientes no es homogénea sobre la superficie estelar y las variaciones observadas serían una consecuencia directa de la rotación estelar. Entre los elementos con abundancia anómala se encuentra el Helio, cuyas líneas tienen intensidades que no son consistentes con una abundancia normal, que no puede ser determinada del modo usual, o sea, considerando una atmósfera con composición solar. Con el fin de determinar la abundancia de este elemento, se inició un estudio de estrellas anómalas de Helio, Hew y He strong. Además se determinarán las abundancias de otros elementos anómalos como ser el Si, Cr, Mg, Mn y Fe. Las mismas se determinan del modo tradicional, o sea: a) medida de los anchos equivalentes de las líneas de los distintos elementos analizados; b) adopción de la temperatura efectiva, gravedad y abundancia del Helio; c) cálculo del modelo de atmósfera d) comparación con las observaciones y reinicio de un proceso iterativo hasta lograr un acuerdo entre todos los parámetros analizados. Las observaciones se llevaron a cabo en el Complejo Astronómico El Leoncito. Se observaron setenta y ocho estrellas anómalas de Helio. En este momento se está procediendo a calcular las abundancias correspondientes a los distintos elementos químicos. Para ello se hace uso de los modelos de Kurucz, ATLAS9. Los cálculos NLTE de las líneas de Helio se llevan a cabo con el programa MULTI y se compararán con los realizados con el programa WIDTH9 de Kurucz (LTE), con el objeto de resaltar la importancia de los efectos NLTE.

  18. Ácaros del mango

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Los ácaros constituyen un grupo abundante y diverso que ocupa diferentes hábitats en árboles frutales y la estructura y disposición del follaje y ramas del mango, contribuyen significativamente a que se presente gran diversidad de ácaros benéficos y dañinos asociados a esta especie frutal. En Colomb...

  19. Estudo de soluções locais e cosmológicas em teorias do tipo tensor-escalar

    NASA Astrophysics Data System (ADS)

    Silva E Costa, S.

    2003-08-01

    Teorias do tipo tensor-escalar são a mais simples extensão possí vel da Relatividade Geral. Nessas teorias, cujo modelo padrão é a teoria de Brans-Dicke, a curvatura do espaço-tempo, descrita por componentes tensoriais, aparece acoplada a um campo escalar que, de certo modo, representa uma variação na constante de acoplamento da gravitação. Tais teorias apresentam soluções locais e cosmológicas que, em determinados limites, recaem nas apresentadas pela Relatividade Geral, mas que em outros limites trazem novidades, tais como conseqüências observacionais da evolução de flutuações primordiais distintas daquelas previstas pela Relatividade Geral (ver, por ex., Nagata et al., PRD 66, p. 103510 (2002)). Graças a esta possibilidade de trazer à luz novidades em relação à gravitação, teorias do tipo tensor-escalar podem ser vistas como um interessante campo alternativo de pesquisas para soluções dos problemas de massa faltante (ou escura) e/ou energia escura. Seguindo tal linha, este trabalho, ainda em sua fase inicial, apresenta soluções gerais de teorias do tipo tensor-escalar para diversas situações, verificando-se em que consiste a divergência dessas soluções dos casos tradicionais possí veis na Relatividade Geral. Como exemplos das soluções aqui apresentadas pode-se destacar uma expressão geral para diferentes soluções cosmológicas englobando diferentes tipos de matéria (representados por diferentes equações de estado), e a expressão para uma solução local representando um buraco negro com rotação, similar à solução de Kerr da Relatividade Geral. Por fim, é importante ressaltar que, embora aqui apresentem-se poucos resultados novos, na literatura sobre o assunto a maior parte das soluções apresentadas limita-se a uns poucos casos especí ficos, tal como soluções cosmológicas apenas com curvatura nula, e que mesmo as soluções disponí veis são, em geral, pouco divulgadas e, portanto, pouco conhecidas, e é tal situação que este trabalho busca, em parte, reverter.

  20. Distribute The Highest Selected Textual Recommendation (DTHSTR)

    Energy Science and Technology Software Center (ESTSC)

    2012-05-01

    The DTHSTR computer code uses a set of documents as seed documents to recommend documents of interest from a large, target set of documents. The computer code provides results that show the highest recommended documents as well as the terms in common between the recommend document and the corresponding seed document that is most similar.

  1. [Textual Research on Wang Fengchun's Life].

    PubMed

    Wang, Ti

    2012-01-01

    WANG Fengchun (1884 - 1949), born in Wu County, Jiangsu Province, was one of the four famous doctors of Beijing in the Republic of China periods. He learned Confucianism during his childhood and then learned medicine from AI Buchan, a famous doctor in Wuzhong area. In 1908, he went to Beijing and was appointed as the prosecutor of the court of law and a medical official, but also had learnt medicine from LI Jun, the head of the Business Ministry. In 1910, Wang resigned and lived as doctor in Beijing. According to the literature, from 1935 to 1942, Wang had been appointed 11 times as a member of Beiping (Beijing) TCM examination committee or test committee. In 1938, he was appointed as president of the Beijing Branch of the National Medical Professional Association and created the Beijing Medicine Monthly in 1939. In September 1939, Wang began to make preparations for a TCM symposium, i.e. the Medicine Symposium which was established officially in October 1939. In 1941, he was appointed as the director of the Beijing Traditional Chinese Medicines Workshop, employing famous doctors to cultivate reserve talents of medicines. Being a realist, he often exchanged opinions with TCM and western medical doctors and also made a contribution to medical education. PMID:22613482

  2. Accessing textual information embedded in Internet images

    NASA Astrophysics Data System (ADS)

    Antonacopoulos, Apostolos; Karatzas, Dimosthenis; Ortiz-Lopez, Jordi

    2000-12-01

    Indexing and searching for WWW pages is relying on analyzing text. Current technology cannot process the text embedded in images on WWW pages. This paper argues that this is a significant problem as text in image form is usually semantically important (e.g. headers, titles). The results of a recent study are presented to show that the majority (76%) of words embedded in images do not appear elsewhere in the main text and that the majority (56%) of ALT tag descriptions of images are incorrect of do not exist at all. Research under way to devise tools to extracted text from images based on the way humans perceive color differences is outlined and results are presented.

  3. Textual Carnivals: The Politics of Composition.

    ERIC Educational Resources Information Center

    Miller, Susan

    This book examines the status of composition in English studies and the uneasy relationship between composition and literature. The three parts of the book (entitled "Where the Carnival Has Been,""The Carnival in the Great American Theme Park: Established Composition," and "Alternative Entertainments") seek to clarify the historical and political…

  4. [Textual research for Tibetan medicine Qumazi].

    PubMed

    Luo, Wu-zheng; Li, Qi-en; Chen, Jing; Dor, Jerenchen; Tao, Si-yu; Shi Jin-bo; Xu, Ying-zhou; Yan, Xing-li

    2015-05-01

    Qumazi is a commonly used Tibetan medicine. With a long history, it can be found in the Four Medical Tantras written by gYu-thog rNying-ma Yon-tan mGon-po since the 8th century AD. Qumazi grows in mudflats and fields, including species growing in highlands, lowlands, mountains and farmlands. According to records in Crystal Beads Materia Medica, it features green sword-shaped leaves, thin stems with red veins, inserted panicles, white chicken-like flowers and copper needle row-like roots. However, there are many inconsistent morphological descriptions for Qumazi plants in many Chinese versions of Tibetan medicine books. In this article, after studying ancient and modern Tibetan medicine books, consulting experts and conducting surveys, the authors confirmed that Qumazi belongs to Rheum of Polygonaceae, including Rheum nobile Hook. f. et. Thoms, R. globulosum Gage, R. alexandrae Hook. f. et. Thoms, R. pumilum Maxim and R. delavayi Franch. In some regions, Qumazi is substituted by R. spiciforme Royle and R. przewalskyi Losinsk. After the Chinese version of Qinghai-Tibet Plateau Drug Illustrations was published in 1972, Qumazi has been miswritten as P. sibiricum Laxm in many Chinese versions of Tibetan medicine books, perhaps because P. sibiricum Laxm has many similar features with Qumazi as described in Crystal Beads Materia Medica and then is mistranslated from Tibetan to Chinese versions. According to records, Qumazi can reduce edema and is mainly applied to treat the minamata disease in clinic. PMID:26390671

  5. Hypermedia as a Medium for Textual Resistance.

    ERIC Educational Resources Information Center

    Barrell, Barrie R. C.; Hammett, Roberta F.

    1999-01-01

    Investigates how technology can be integrated into existing secondary English language arts curricula in ways that avoid the perpetuation of social injustice, withstand inequalities, and resist false commercial ideologies. Describes preservice English teachers' web pages constructed in response to E. Anne Proulx's novel "The Shipping News." (NH)

  6. PREVENCIÓN DEL VIH/SIDA EN LOS CIRCUITOS DE LEVANTE HSH: UNA ASIGNATURA PENDIENTE1

    PubMed Central

    Barreda, Victoria; Carballo-Dieguez, Alex; Marone, Rubén; Balán, Iván; Pando, María Ángeles; Ávila, María Mercedes

    2011-01-01

    Resumen A partir de un relevamiento de tipo etnográfico, se describen lugares de encuentro de HSH en la Ciudad de Buenos Aires y sus prácticas sexuales. El reconocimiento de tales espacios, así como las características que asumen en ellos los encuentros sexuales entre los HSH, plantean obstáculos específicos en la adopción de comportamientos preventivos y, asimismo, generan nuevos desafíos para las actividades de prevención. Se plantean las dificultades y debates conceptuales que la misma categoría presenta, y sus consecuencias en el abordaje preventivo y teórico-metodológico para las ciencias sociales. Además, se proponen nuevos interrogantes acerca de los alcances y las limitaciones del modelo preventivo del VIH/Sida para HSH. PMID:21874154

  7. Case Study: del Amo Bioventing

    EPA Science Inventory

    The attached presentation discusses the fundamentals of bioventing in the vadose zone. The basics of bioventing are presented. The experience to date with the del Amo Superfund Site is presented as a case study.

  8. Estudio multiespectral del remanente de supernova W 28

    NASA Astrophysics Data System (ADS)

    Dubner, G.; Velázquez, P.; Castelletti, G.

    Se presentan observaciones en continuo de radio con muy alta resolución angular y sensibilidad del remanente de supernova (RSN) W28. Las observaciones fueron realizadas con el interferómetro Very Large Array (Estados Unidos), en las configuraciones C y D, en 1415 y 324 MHz. Por la gran extensión de este remanente (diámetro ~ 1o), las observaciones en 1415 MHz se realizaron en modo mosaico, combinando 48 apuntamientos diferentes en una única imagen. En ambas frecuencias los datos se procesaron con el agregado de observaciones de menor resolución angular, a fin de recuperar información en todas las frecuencias espaciales y obtener estimaciones precisas de densidad de flujo. Las imágenes resultantes muestran por primera vez la presencia de extensiones con forma de arco, cuya naturaleza se investiga. Las observaciones en radio se comparan con una imagen óptica de W28, y con la emisión en rayos X, observada con el satélite ROSAT. Este remanente muestra una clara morfología híbrida, tipo cáscara en frecuencias de radio y de centro lleno en las bandas óptica y de rayos X blandos.

  9. IL TRAPIANTO ORTOTOPICO DEL FEGATO

    PubMed Central

    STARZL, THOMAS E.

    2010-01-01

    E’ormai noto che esiste la possibilità rivoluzionaria di utilizzare il fegato per il trattamento della stadio terminale delle epatopatie. Nel gennaio 1980 si celebra il decimo anna di sopravvivenza con fegato trapiantato (la più lunga della letteratura) di un paziente da noi trattato. Si tratta di uno dei 12 malati sottoposti a trapianto e seguiti per più di 5 anni. La nota positiva di questa tipo di trattamento è rappresentata dall’eccellente tenore di vita che i pazienti conducono e dalla riabilitazione sociale e professionale. La nota negativa è data, invece, dal fatto che i buoni risultati non vengono raggiunti con regolarità e non possono essere previsti con esattezza. In questa breve rassegna considereremo la esperienza da noi fatta presso l’Università di Denver nel Colorado, mettendo in risalto le cause dell’elevata mortalità precoce e le prospettive future di questa mezzo terapeutico. PMID:21572898

  10. Segundo Catálogo Estelar del Hemisferio Sur con Astrolabio Fotoeléctrico PAII

    NASA Astrophysics Data System (ADS)

    Manrique, W. T.; Podestá, R. C.; Alonso, E.; Actis, E. V.; Pacheco, A. M.; Bustos, G.; Lizhi, L.; Zezhi, W.; Fanmiao, Z.; Hongqi, W.; Perdomo, R.

    Recordamos que entre el Observatorio Astronómico ``Félix Aguilar'', el Observatorio Astronómico de Beijing y el Observatorio Astronómico de La Plata, se ha convenido en desarrollar un Proyecto de Investigación conjunto, para la observación sistemática de estrellas en el Hemisferio Sur, con el objeto de la elaboración de un Catálogo Estelar Global utilizando un Astrolabio Fotoeléctrico PAII del Observatorio de Beijing, que ha sido usado con éxito en la República de China. En este trabajo se presenta el Segundo Catálogo Estelar del Hemisferio Sur, derivado de las observaciones realizadas con el PAII instalado en el OAFA, durante el períiodo Febrero de 1992 a Marzo de 1997. En este lapso se han observado mas de 400000 pasajes estelares, obteniéndose las correcciones Δ α y Δ δ de 5241 estrellas del FK4, FK5, FK5 Ext., SRS, CAMC y GC. Las precisiones medias son del orden de ± 3,2 ms en ascensión recta y ±0."057 en declinación. Rango de magnitudes : 2,0 a 11,5 Rango de declinaciones : -3o a -60o Epoca Media : 1994.9 Se analizan los residuos en función de la magnitud y tipo espectral, correcciones de grupo y frecuencia de distribución Δ α y Δ δ.

  11. Del Pezzo surfaces with Du Val singularities

    NASA Astrophysics Data System (ADS)

    Kosta, Dimitra

    2009-04-01

    In this paper we study the problem of existence of orbifold Kaehler-Einstein metrics on del Pezzo surfaces of degree 1 with Du Val singular points. Moreover we compute global log canonical thresholds of del Pezzo surfaces of degree 1 with Du Val singularities and of del Pezzo surfaces of Picard rank 1 with Du Val singularities.

  12. del, truth & proof

    NASA Astrophysics Data System (ADS)

    Peregrin, Jaroslav

    2007-11-01

    The usual way of interpreting Gödel's (1931) incompleteness result is as showing that there is a gap between truth and provability, i.e. that we can never prove everything that is true. Moreover, this result is supposed to show that there are unprovable truths which we can know to be true. This, so the story goes, shows that we are more than machines that are restricted to acting as proof systems. Hence our minds are 'not mechanical'.

  13. Mal del pinto in Mexico*

    PubMed Central

    Marquez, Francisco; Rein, Charles R.; Arias, Oswaldo

    1955-01-01

    This report deals with the geographical distribution, prevalence, epidemiology, etiology, serological, clinical, and histopathological features, and treatment of mal del pinto, or pinta, in Mexico. Repository penicillin preparations (PAM and Panbiotic) have been found highly effective in the treatment of this endemic, non-venereal treponematosis. ImagesFIG. 1FIG. 2FIG. 3FIG. 4FIG. 5FIG. 6FIG. 7FIG. 8 PMID:13260889

  14. Tierra del Fuego, Argentina, South America

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The Mitre Peninsula is the easternmost tip of Tierra del Fuego, Argentina, (54.5S, 65.5W). Early winter snow can be seen on this south tip of the Andes Mountains. These same mountains continue underwater to Antarctica. The Strait of Magellan, separating the South American mainland from Tierra del Fuego is off the scene to the north and west, but the Strait of LeMaire, separating Tierra del Fuego from the Isla de los Estados can be seen.

  15. 33 CFR 80.1118 - Marina Del Rey, CA.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Marina Del Rey, CA. 80.1118... NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Coast § 80.1118 Marina Del Rey, CA. (a) A line drawn from Marina Del Rey Breakwater South Light 1 to Marina Del Rey Light 4. (b) A line drawn from Marina Del...

  16. 33 CFR 80.1118 - Marina Del Rey, CA.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Marina Del Rey, CA. 80.1118... NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Coast § 80.1118 Marina Del Rey, CA. (a) A line drawn from Marina Del Rey Breakwater South Light 1 to Marina Del Rey Light 4. (b) A line drawn from Marina Del...

  17. 33 CFR 80.1118 - Marina Del Rey, CA.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Marina Del Rey, CA. 80.1118... NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Coast § 80.1118 Marina Del Rey, CA. (a) A line drawn from Marina Del Rey Breakwater South Light 1 to Marina Del Rey Light 4. (b) A line drawn from Marina Del...

  18. Control del cáncer y salud mundial: noticia del Instituto Nacional del Cáncer (NCI)

    Cancer.gov

    En combinación con una reunión de alto nivel de las Naciones Unidas sobre enfermedades no transmisibles en países en vías de desarrollo, el doctor Harold Varmus, director del NCI, y el doctor Ted L. Trimble, del NCI, han publicado un comentario en Science

  19. Líneas Vitales: Programas y servicios del NCI

    Cancer.gov

    Artículos y videos sobre los programas y servicios del Instituto Nacional del Cáncer de la serie educativa Líneas Vitales del NCI, la cual está dirigida especialmente a poblaciones multiculturales.

  20. Descripción del coronógrafo a ser instalado en Argentina (MICA)

    NASA Astrophysics Data System (ADS)

    Stenborg, G.; Francile, C.; Schwenn, R.; Epple, A.; Rovira, M.

    El ``Coronógrafo de espejo para Argentina'' es un telescopio solar terrestre a ser colocado en el Observatorio Astronómico Félix Aguilar (El Leoncito), antes de finalizar 1996, como parte de un programa de ciencia bilateral entre Alemania y Argentina. Eclipses fotográficos de alta resolución han revelado que la corona solar es altamente estructurada y variable. De hecho, está contínuamente deformada y moldeada por los movimientos convectivos de los extremos de los arcos magnéticos en la fotosfera, estando, en muchas oportunidades, afectada por explosivas liberaciones de energía. MICA, en conjunción con otros telescopios solares espaciales y terrestres, tratará de contribuir al entendimiento de cuestiones fundamentales de la física solar. Entre ellas: cómo la corona está siendo calentada, dónde y cómo el viento solar es acelerado, qué causa los transitorios coronales, etc. Para ello investigará la distribución de los parámetros del plasma y su evolución con el tiempo, la estructura espacial de la corona en fina y gran escala, procesos que ocurren en los transitorios coronales y factores que los disparan, etc. Para responder a estas cuestiones MICA observará la atmósfera solar por sobre el limbo entre 1.1 y 2 radios solares aproximadamente, usando un nuevo tipo de sistema coronográfico que permite suprimir el brillo del disco solar suficientemente bien, tomando las imágenes con una cámara CCD de 1024x1024 pixels, codificada en 12 bits, pudiendo el mismo ser operado en forma remota. En la presente exposición describiremos las características del instrumento, cómo será controlado y qué esperamos observar basados en las imágenes obtenidas por los telescopios de similares características LASCO C1 a bordo del SOHO y PICO (ubicado en el Observatorio de Pic du Midi, Francia).

  1. Produccion Gaseosa del Cometa Halley: Erupciones Y Fotodisociacion del Radical OH

    NASA Astrophysics Data System (ADS)

    Silva, A. M.; Mirabel, I. F.

    1990-11-01

    RESUMEN:En este trabajo informamos la detecci6n de 20 erupciones en la li'nea de =18cm (1667MHz) del radical OH en el Cometa Halley.Las observaciones incluyen todos los monitoreos existentes y se extienden desde 120 dias antes del perihelio hasta 90 dias despues.Se detectan bruscos crecimientos en el flujo medido,hasta un factor 1O,seguidos por decaimientos lentos asociados con la fotodisociaci6n del OH. Se obtuvieron valores para el tiempo de vida fotoquimico del OH y del H2O basandose en el modelo desarrollado previamente por Silva(1988). Esos tiempos de vida estan de acuerdo con predicciones teoricas y con las observaciones en el Ultravioleta, y los resultados, los que son fuertemente dependientes de la velocidad heliocentrica del Coineta (variando hasta un factor 6), han sido calculados para varios rangos de velocidad entre +28 y -28 km/seg. Key wo'L :

  2. Gonadal dysgenesis in del (18p) syndrome

    SciTech Connect

    Telvi, L.; Ion, A.; Fouquet, F.

    1995-07-17

    We report on a girl with syndromal gonadal dysgenesis and a de novo del (18p). Genetic factors controlling gonadal development are located not only on the X chromosome, but also on autosomes. The present case suggests that one of these genes is situated on 18p. We conclude that patients with del (18p) syndrome should be evaluated for gonadal dysgenesis. 16 refs., 3 figs.

  3. Análise Temporal de Estruturas Morfológicas na Cauda do Tipo I do Cometa P/Halley

    NASA Astrophysics Data System (ADS)

    Voelzke, M. R.; Matsuura, O. T.

    1996-08-01

    Com base em (Brandt et al, 1992), centenas de imagens do cometa P/Halley foram visualmente analisadas, objetivando examinar possíveis perturbações magnetohidrodinâmicas ao longo da cauda do tipo I. Do total de 1439 imagens, abrangendo o período entre 16 de outubro de 1982 e 12 de fevereiro de 1991, foram escolhidas 531 do período entre 17 de setembro de 1985 e 06 de julho de 1986 por mostrarem cauda bem desenvolvida e rica de estruturas morfológicas. Nelas constatou-se a existência de 124 estruturas ondulatórias (trens de onda) ao longo da cauda principal, 27 ao longo de caudas secundárias, 109 ondas solitárias (sólitons) ao longo da cauda principal, 36 ao longo de caudas secundárias, 12 caudas do tipo Swan, 47 eventos de desconexão e 23 regiões de adensamento ("knots"). Foi examinada a correlação temporal entre esses diferentes tipos de eventos. Os de desconexão foram analisados isoladamente. Seus movimentos próprios foram calculados, bem como os seus instantes iniciais, o que nos permitiu inferir a passagem do cometa pela fronteira entre setores magnéticos distintos. A velocidade do plasma cometário desconectado foi corrigida dos efeitos de projeção e correlacionada com a distância heliocêntrica do cometa. Também foi investigada a periodicidade de ocorrência das desconexães, e constatado que sua distribuição é bimodal. Por fim, a possibilidade dos modos de propagação de ondas MHD "sausage" e "kink" superficiais ou volumétricas, é discutida no contexto das descontinuidades magnéticas tangenciais. - Brandt, J.C., Niedner Jr., M.B., Rahe, J.: The International Halley Watch Atlas of Large-Scale Phenomena. Impresso por: Johnson Printing Co, Boulder, CO. University of Colorado-Boulder, 1992.

  4. "Processing Instruction": un tipo di grammatica comunicativa per la classe di lingua straniera. Il caso del futuro italiano. (Processing Instruction: One Type of Communicative Grammar for the Foreign Language Classroom. The Case of the Italian Future Tense).

    ERIC Educational Resources Information Center

    Benati, Alessandro

    2000-01-01

    Examines the theoretical and practical rationale for processing instruction as a method of incorporating grammar instruction in a communicative foreign language approach. Presents results of a study on the role of processing instruction on the learning of the Italian future indicative tense by a group of English-speaking students. Results…

  5. Intertextual Sexual Politics: Illness and Desire in Enrique Gomez Carrillo's "Del amor", "del dolor y del vicio" and Aurora Caceres's "La rosa muerta"

    ERIC Educational Resources Information Center

    LaGreca, Nancy

    2012-01-01

    This study explores the intertextuality between Aurora Caceres's "La rosa muerta" (1914) and the novel "Del amor, del dolor y del vicio" (1898) by her ex-husband, Enrique Gomez Carrillo. Caceres strategically mentions Gomez Carrillo's novel in "La rosa muerta" to invite a reading of her work in dialogue with his. Both narratives follow the sexual…

  6. Intertextual Sexual Politics: Illness and Desire in Enrique Gomez Carrillo's "Del amor", "del dolor y del vicio" and Aurora Caceres's "La rosa muerta"

    ERIC Educational Resources Information Center

    LaGreca, Nancy

    2012-01-01

    This study explores the intertextuality between Aurora Caceres's "La rosa muerta" (1914) and the novel "Del amor, del dolor y del vicio" (1898) by her ex-husband, Enrique Gomez Carrillo. Caceres strategically mentions Gomez Carrillo's novel in "La rosa muerta" to invite a reading of her work in dialogue with his. Both narratives follow the sexual

  7. Visiting the Gödel universe.

    PubMed

    Grave, Frank; Buser, Michael

    2008-01-01

    Visualization of general relativity illustrates aspects of Einstein's insights into the curved nature of space and time to the expert as well as the layperson. One of the most interesting models which came up with Einstein's theory was developed by Kurt Gödel in 1949. The Gödel universe is a valid solution of Einstein's field equations, making it a possible physical description of our universe. It offers remarkable features like the existence of an optical horizon beyond which time travel is possible. Although we know that our universe is not a Gödel universe, it is interesting to visualize physical aspects of a world model resulting from a theory which is highly confirmed in scientific history. Standard techniques to adopt an egocentric point of view in a relativistic world model have shortcomings with respect to the time needed to render an image as well as difficulties in applying a direct illumination model. In this paper we want to face both issues to reduce the gap between common visualization standards and relativistic visualization. We will introduce two techniques to speed up recalculation of images by means of preprocessing and lookup tables and to increase image quality through a special optimization applicable to the Gödel universe. The first technique allows the physicist to understand the different effects of general relativity faster and better by generating images from existing datasets interactively. By using the intrinsic symmetries of Gödel's spacetime which are expressed by the Killing vector field, we are able to reduce the necessary calculations to simple cases using the second technique. This even makes it feasible to account for a direct illumination model during the rendering process. Although the presented methods are applied to Gödel's universe, they can also be extended to other manifolds, for example light propagation in moving dielectric media. Therefore, other areas of research can benefit from these generic improvements. PMID:18989011

  8. Calidad de Imagen del Telescopio UNAM212

    NASA Astrophysics Data System (ADS)

    Cobos, F. J.; Teiada de Vargas, C.

    1987-05-01

    El telescopio UNAM2l2, del Observatorio Astronómico Nacional, situado en la Sierra de San Pedro Mártir (Baja California, México), cumplira en un futuro muy cercano siete años de uso para fines de investigación astronómica. Aunque en este tiempo no se ha efectuado un estudio sistemático acerca de su comportamiento óptico y de los factores que influyen en la calidad de las imágenes, se han realizado pruebas diversas, estudios parciales y reuniones especificas, cuyos resultados no siempre se han difundido ampliamente y generalmente no se han presentado por escrito. Es por ello que hemos creido necesario intentar una recopilación de la información existente para poder con ella establecer un diagnóstjco que, aunque no sea definitivo, sirva de base para futuros trabajos tendientes a optimizar el comportamiento óptico del telescopio. Es evidente que un buen número de las conclusiones que se presentan son resultado del trabajo de muchas personas ó de esfuerzos colectivos. Asimismo, hemos tratado de localizar información bibliográfica que pueda ser de utilidad. Nuestro objetivo primordial ha consistido en centrarnos en la óptica del telescopio y su calidad, pero también se han considerado otros aspectos que puedan afectar las imágenes obtenidas tales como: celda del primario, `seeing' local y externo, flexiones posibles en la estructura mecánica del telescopio, etc.

  9. Radio-Observaciones del OH EN la Coma del Cometa Halley Desde EL Hemisferio Sur

    NASA Astrophysics Data System (ADS)

    Silva, A. M.; Bajaja, E.; Morras, R.; Cersosimo, J. C.; Martin, M. C.; Arnal, E. M.; Poppel, W. G. L.; Colomb, F. R.; Mazzaro, J.; Olalde, J. C.; Boriakoff, V.; Mirabel, I. F.

    1987-05-01

    Se utilizó una antena de 30 metros del Instituto Argentino de Radioastronomía para observaciones diarias Cf ebrero a abril de 1986) de la transición en 1667 MHz ( λ = 18 cm) del OH en la coma del cometa Halley. De las observaciones realizadas se concluye: 1) El número promedio de moléculas de OH en la coma durante 37 días de observación fue de (8.9±3.5)x1034 moléculas, lo que implica una tasa de producción promedio de OH de 1.8x1029 moléculas seg-1 y consecuentemente una pérdida de masa promedio de 17±6 toneladas seg-1 . Este valor está de acuerdo con las mediciones realizadas por las sondas Vega y Giotto. 2) El monitoreo desde el lAR revela la existencia de variaciones bruscas en los flujos de absorción del OH. Estas variaciones son consistentes con los modelos que representan la producción gaseosa a partir de ejecciones y/o desprendimientos discretos de materia congelada del núcleo. 3) Las variaciones en la densidad de flujo son consistentes con las estimaciones de los tiem- pos de vida medios del H2O y del OH en presencia del campo de radiación solar. 4) Se encuentra una correlación entre la intensidad del flujo absorbido y anisotropías en Ia dinamica de la coma.

  10. Composição química, evolução e cinemática de estrelas de tipo solar

    NASA Astrophysics Data System (ADS)

    Silva, R. O.; Porto de Mello, G. F.; Milone, A. C.

    2003-08-01

    A composição química das estrelas de tipo solar é um diagnóstico extremamente valioso da evolução química do disco da Galáxia. Existe alguma evidência de que tal evolução tem sido heterogênea no espaço e ao longo do tempo e que a composição química do Sol pode não ser um padrão representativo de abundâncias. Neste trabalho, foram obtidas as abundâncias dos elementos químicos C, N, Na, Mg, Si, Ca, Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Sr, Y, Zr, Ba, La, Ce, Nd e Sm em uma amostra de estrelas de tipo solar na vizinhança solar (distâncias £ 25 pc). A técnica empregada foi a análise espectroscópica diferencial em relação ao Sol, baseando-se em dados de alta resolução (R ~ 46.000) e alta razão sinal/ruído (S/R > 300), obtidos com o espectrógrafo échelle de bancada do telescópio de 1,5 m do CTIO. Adicionalmente, abundâncias de C e N foram obtidas através de síntese de bandas moleculares dos Sistemas Eletrônicos Swan do C2 e Vermelho do CN utilizando-se um programa de síntese espectral. Os parâmetros atmosféricos foram estabelecidos usando cores fotométricas, o equilíbrio de excitação e ionização de linhas do Fe e a análise da temperatura e da luminosidade estelares no diagrama HR. Os resultados de abundâncias químicas obtidos proporcionam uma melhor compreensão da relação das abundâncias conhecidas para o Sol com a das estrelas anãs de tipo G da população local, uma vez que as razões de abundâncias de diversos elementos (em relação ao ferro) obtidas para estrelas de metalicidade semelhante à solar diferem daquelas obtidas para o Sol. Tais resultados também contribuem para um melhor entendimento do processo de evolução química da vizinhança solar e do enriquecimento nucleossintético do disco galáctico.

  11. Educational and Demographic Profile: Del Norte County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Del Norte County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  12. PASO DEL NORTE SUMMER OZONE STUDY

    EPA Science Inventory

    The Paso del Norte Summer Ozone Study was designed to evaluate potential control strategies for their efficacy in reducing ozone and carbon monoxide concentrations in the El Paso-Ciudad Juarez-Sunland Park international airshed of Texas, New Mexico, and Chihuahua. A field study ...

  13. Near Infrared Photometry of Nova Del 2013

    NASA Astrophysics Data System (ADS)

    Cass, A. C.; Carlon, R. L.; Corgan, D. T.; Dykhoff, D. A.; Gehrz, R. D.; Shenoy, D. P.

    2013-09-01

    We continued to follow Nova Del 2013 during the period from 31.15 August 2013 UT through 25.18 September 2013 UT using an As:Si bolometer mounted on the 0.76-m infrared telescope of the University of Minnesota's O'Brien Observatory (Marine on St. Croix, Minnesota, USA). Vega (alpha Lyrae) is used as the standard star.

  14. Vigilando la Calidad del Agua de los Grandes Rios de la Nacion: El Programa NASQAN del Rio Grande (Rio Bravo del Norte)

    USGS Publications Warehouse

    Lurry, Dee L.; Reutter, David C.; Wells, Frank C.; Rivera, M.C., (translator); Munoz, A.

    1998-01-01

    La Oficina del Estudio Geologico de los Estados Unidos (U.S. Geological Survey, 0 USGS) ha monitoreado la calidad del agua de la cuenca del Rio Grande (Rio Bravo del Norte) desde 1995 como parte de la rediseiiada Red Nacional para Contabilizar la Calidad del Agua de los Rios (National Stream Quality Accounting Network, o NASOAN) (Hooper and others, 1997). EI programa NASOAN fue diseiiado para caracterizar las concentraciones y el transporte de sedimento y constituyentes quimicos seleccionados, encontrados en los grandes rios de los Estados Unidos - incluyendo el Misisipi, el Colorado y el Columbia, ademas del Rio Grande. En estas cuatro cuencas, el USGS opera actualmente (1998) una red de 40 puntos de muestreo pertenecientes a NASOAN, con un enfasis en cuantificar el flujo en masa (la cantidad de material que pasa por la estacion, expresado en toneladas por dial para cada constituyente. Aplicacando un enfoque consistente, basado en la cuantificacion de flujos en la cuenca del Rio Grande, el programa NASOAN esta generando la informacion necesaria para identificar fuentes regionales de diversos contaminantes, incluyendo sustancias qui micas agricolas y trazas elementos en la cuenca. EI efecto de las grandes reservas en el Rio Grande se puede observar segun los flujos de constituyentes discurren a 10 largo del rio. EI analisis de los flujos de constituyentes a escala de la cuenca proveera los medios para evaluar la influencia de la actividad humana sobre las condiciones de calidad del agua del Rio Grande.

  15. Everyday Creativity in Language: Textuality, Contextuality, and Critique

    ERIC Educational Resources Information Center

    Maybin, Janet; Swann, Joan

    2007-01-01

    This paper starts by examining recent work by applied linguists who argue that creativity is not only a property of especially skilled and gifted language users, but is pervasive in routine everyday practice. Also variously addressing literariness, language play and humour, this apparent democratization of creativity contributes to a more general…

  16. Constructing and Analyzing Uncertain Social Networks from Unstructured Textual Data

    NASA Astrophysics Data System (ADS)

    Johansson, Fredrik; Svenson, Pontus

    Social network analysis and link diagrams are popular tools among intelligence analysts for analyzing and understanding criminal and terrorist organizations. A bottleneck in the use of such techniques is the manual effort needed to create the network to analyze from available source information. We describe how text mining techniques can be used for extraction of named entities and the relations among them, in order to enable automatic construction of networks from unstructured text. Since the text mining techniques used, viz. algorithms for named entity recognition and relation extraction, are not perfect, we also describe a method for incorporating information about uncertainty when constructing the networks and when doing the social network analysis. The presented approach is applied on text documents describing terrorist activities in Indonesia.

  17. Agent-based method for distributed clustering of textual information

    DOEpatents

    Potok, Thomas E. [Oak Ridge, TN; Reed, Joel W. [Knoxville, TN; Elmore, Mark T. [Oak Ridge, TN; Treadwell, Jim N. [Louisville, TN

    2010-09-28

    A computer method and system for storing, retrieving and displaying information has a multiplexing agent (20) that calculates a new document vector (25) for a new document (21) to be added to the system and transmits the new document vector (25) to master cluster agents (22) and cluster agents (23) for evaluation. These agents (22, 23) perform the evaluation and return values upstream to the multiplexing agent (20) based on the similarity of the document to documents stored under their control. The multiplexing agent (20) then sends the document (21) and the document vector (25) to the master cluster agent (22), which then forwards it to a cluster agent (23) or creates a new cluster agent (23) to manage the document (21). The system also searches for stored documents according to a search query having at least one term and identifying the documents found in the search, and displays the documents in a clustering display (80) of similarity so as to indicate similarity of the documents to each other.

  18. Star Trek Rerun, Reread, Rewritten: Fan Writing as Textual Poaching.

    ERIC Educational Resources Information Center

    Jenkins III, Henry

    1988-01-01

    Discusses women who write fiction and fan literature based on the "Star Trek" universe, outlining how Star Trek fans force the primary text to accommodate alternate interests. Also considers the issue of literary property in light of the moral economy of the fan community that shapes the range of permissible retellings of the program materials.

  19. Combination of visual and textual similarity retrieval from medical documents.

    PubMed

    Eggel, Ivan; Müller, Henning

    2009-01-01

    Medical visual information retrieval has been an active research area over the past ten years as an increasing amount of images are produced digitally and have become available in patient records, scientific literature, and other medical documents. Most visual retrieval systems concentrate on images only, but it has become apparent that the retrieval of similar images alone is of limited interest, and rather the retrieval of similar documents is an important domain. Most medical institutions as well as the World Health Organization (WHO) produce many complex documents. Searching them, including a visual search, can help finding important information and also facilitates the reuse of document content and images. The work described in this paper is based on a proposal of the WHO that produces large amounts of documents from studies but also for training. The majority of these documents are in complex formats such as PDF, Microsoft Word, Excel, or PowerPoint. Goal is to create an information retrieval system that allows easy addition of documents and search by keywords and visual content. For text retrieval, Lucene is used and for image retrieval the GNU Image Finding Tool (GIFT). A Web 2.0 interface allows for an easy upload as well as simple searching. PMID:19745431

  20. The Textuality of Learning Contexts in UK Colleges

    ERIC Educational Resources Information Center

    Satchwell, Candice; Ivanic, Roz

    2007-01-01

    A significant aspect of learning contexts is the way in which semiotic artefacts mediate learning within them. This article reports on the "Literacies for Learning in Further Education" (LfLFE) project in the UK, which has researched the role of texts and associated communicative practices in constructing and mediating teaching and learning;

  1. Applications of N-Grams in Textual Information Systems.

    ERIC Educational Resources Information Center

    Robertson, Alexander M.; Willett, Peter

    1998-01-01

    An n-gram is a string of characters, usually adjacent, extracted from a section of continuous text that can be used in spelling error detection and correction, query expansion, information retrieval, dictionary search, text compression, and language identification applications. This article provides an introduction to the use of n-grams in textual…

  2. The Semantic Effects of Consulting a Textual Database on Rewriting.

    ERIC Educational Resources Information Center

    Crinon, Jacques; Legros, Denis

    2002-01-01

    Children 8 to 10 years old were asked to improve a story they wrote, using computer-provided resource texts, resource texts on paper, or no resource texts. There were 18 children in each group, divided into 3 levels of reading ability. Regardless of ability, children using the computer produced more propositions during writing, and particularly…

  3. Integration of textual guideline documents with formal guideline knowledge bases.

    PubMed Central

    Shankar, R. D.; Tu, S. W.; Martins, S. B.; Fagan, L. M.; Goldstein, M. K.; Musen, M. A.

    2001-01-01

    Numerous approaches have been proposed to integrate the text of guideline documents with guideline-based care systems. Current approaches range from serving marked up guideline text documents to generating advisories using complex guideline knowledge bases. These approaches have integration problems mainly because they tend to rigidly link the knowledge base with text. We are developing a bridge approach that uses an information retrieval technology. The new approach facilitates a versatile decision-support system by using flexible links between the formal structures of the knowledge base and the natural language style of the guideline text. PMID:11825260

  4. Teaching Textual Conversations: Intertextuality in the College Reading Classroom

    ERIC Educational Resources Information Center

    Armstrong, Sonya L.; Newman, Mary

    2011-01-01

    In this article, a model of intertextuality is introduced as an instructional approach for postsecondary developmental reading courses. This model involves a scaffolded, schema building approach to teaching college reading that aims to link core material (a text, a concept, or specific academic content) with supplementary texts that focus on…

  5. Gross's Anatomy: Textual Politics in Science/Biology Education Research

    ERIC Educational Resources Information Center

    Reis, Giuliano

    2009-01-01

    In approaching how the grotesque is--or should be--situated within contemporary science (biology) education practices, Weinstein and Broda undertake a passionate reclaim of an education that is at the same time scientific, critical, and liberatory. However legitimate, their work offers more than they probably could have anticipated: It exemplifies…

  6. Star Trek Rerun, Reread, Rewritten: Fan Writing as Textual Poaching.

    ERIC Educational Resources Information Center

    Jenkins III, Henry

    1988-01-01

    Discusses women who write fiction and fan literature based on the "Star Trek" universe, outlining how Star Trek fans force the primary text to accommodate alternate interests. Also considers the issue of literary property in light of the moral economy of the fan community that shapes the range of permissible retellings of the program materials.…

  7. A Close Textual Analysis of Corporate Layoff Memos

    ERIC Educational Resources Information Center

    Warnick, Quinn

    2010-01-01

    All employers occasionally must deliver bad news to their employees, but few bad news situations can compete with the delicate task of announcing layoffs. In an electronic age, when layoff notices delivered via email are quickly leaked to outsiders, CEOs must take into account not only the employees who will be affected by the layoffs but also the…

  8. [Primary textual research on editions of Lei jing (Classified Canon)].

    PubMed

    Zhao, Hansen; Guo, Ling

    2002-01-01

    There were not a few editions of Lei jing (Classified Canon) spread now, some of which had certain relationship in their origin. The block - printed edition of the Ming dynasty in the ministry library of Japan National Cabinet Document Library may probably be the earliest edition of Lei jing. There were two major types of edition of Lei jing in circulation, that is, the editions with and without the original contents of Nei jing (Inner Canon). The Yongquan edition of Jin Changtong and edition of Tiande Hall were the source of all the block - printed editions in China, while the Japanese block - printed edition was derived from the edition with the original contents of Nei jing of the Ming dynasty. PMID:12015055

  9. A Close Textual Analysis of Corporate Layoff Memos

    ERIC Educational Resources Information Center

    Warnick, Quinn

    2010-01-01

    All employers occasionally must deliver bad news to their employees, but few bad news situations can compete with the delicate task of announcing layoffs. In an electronic age, when layoff notices delivered via email are quickly leaked to outsiders, CEOs must take into account not only the employees who will be affected by the layoffs but also the

  10. Critical Theory & Textual Arguments: Expanding Habermas's Analysis of Literary Claims.

    ERIC Educational Resources Information Center

    Stroud, Scott R.

    Jurgen Habermas's theory of communicative action has held much promise for critical theory and its examination of the structure of society. This theory, however, has been accused by some as being limited in regard to other forms of discourse, especially fictional, mythical, and religious texts. Habermas has argued that literature (i.e., fictive…

  11. Wavelet domain textual coding of Ottoman script images

    NASA Astrophysics Data System (ADS)

    Gerek, Oemer N.; Cetin, Enis A.; Tewfik, Ahmed H.

    1996-02-01

    Image coding using wavelet transform, DCT, and similar transform techniques is well established. On the other hand, these coding methods neither take into account the special characteristics of the images in a database nor are they suitable for fast database search. In this paper, the digital archiving of Ottoman printings is considered. Ottoman documents are printed in Arabic letters. Witten et al. describes a scheme based on finding the characters in binary document images and encoding the positions of the repeated characters This method efficiently compresses document images and is suitable for database research, but it cannot be applied to Ottoman or Arabic documents as the concept of character is different in Ottoman or Arabic. Typically, one has to deal with compound structures consisting of a group of letters. Therefore, the matching criterion will be according to those compound structures. Furthermore, the text images are gray tone or color images for Ottoman scripts for the reasons that are described in the paper. In our method the compound structure matching is carried out in wavelet domain which reduces the search space and increases the compression ratio. In addition to the wavelet transformation which corresponds to the linear subband decomposition, we also used nonlinear subband decomposition. The filters in the nonlinear subband decomposition have the property of preserving edges in the low resolution subband image.

  12. Textual Challenges: A Brief Guide to Choosing Shakespearean Editions

    ERIC Educational Resources Information Center

    Cornell, Christine; Malcolmson, Patrick

    2012-01-01

    How should educators go about selecting appropriate editions of Shakespeare's plays for use in political science courses? Shakespeare is turning up on many politics syllabi, but, at times, the editions chosen seem to reflect primarily a concern for price or publisher reputation over pedagogical and scholarly considerations. This article offers an…

  13. The Love of a Good Narrative: Textuality and Digitality

    ERIC Educational Resources Information Center

    Dobson, Teresa M.

    2006-01-01

    It has often been observed that Alice Munro is a master of narrative complexity. "The love of a good woman", in particular, is a story that challenges conventional notions of structure in short fiction through digression or deferral, discontinuity, layering, and so on. Ross (2002) rightly observes that conventional theories of reading fail to get…

  14. Once Is Not Enough: Statistical Simulation of Textual Data.

    ERIC Educational Resources Information Center

    Hogenraad, Robert

    Reproduction is part of the regulations of daily speech. Everyday experience shows there are different ways to convey the same information: starting sentences that are quickly rephrased using other words, manuscripts passing through draft states before the writer decides upon the final version. In more ways than one, any text is always but the…

  15. Africa and International Policy Making for Lifelong Learning: Textual Revelations

    ERIC Educational Resources Information Center

    Preece, Julia

    2013-01-01

    This paper discusses the relationship between international agendas for lifelong learning and financial aid for low income countries, especially those on the African continent. It argues that there are subtle differences in terminology written by policymakers respectively in Europe and South Africa for lifelong learning but that international

  16. Some Considerations of Intersubjectivity in the Analysis of Textual Relations.

    ERIC Educational Resources Information Center

    Koskela, Merja

    A study explored the reliability of methods for analyzing the thematic organization of texts. Five linguists, two of whom were native speakers of Swedish and three of whom were native speakers of Finnish, analyzed the thematic organization of a Swedish popular scientific article, using an analysis that focused on coherence reflected in the…

  17. Integrating Animations, Narratives and Textual Information for Improving Physics Learning

    ERIC Educational Resources Information Center

    Adegoke, Benson Adesina

    2010-01-01

    Introduction: This article examined the effect of multimedia instruction on students' learning outcomes (achievement and interest) in secondary school physics. Method: The sample comprised of 517 (294 boys and 223 girls) students who came from 12 senior secondary schools in Ibadan Educational Zone 1, Oyo State, Nigeria. Their ages ranged between

  18. Lexical Patterns in L2 Textual Gist Identification Assessment

    ERIC Educational Resources Information Center

    Yamada, Kyoko

    2009-01-01

    Gist identification or coherent situation model construction performance is an important criterion not only in L1 and L2 reading comprehension assessment but also in every aspect of discourse processing. Whereas most previous L2 research has investigated schematic knowledge of readers about relations within a text, more recent studies have used…

  19. Knowledge Discovery in Textual Documentation: Qualitative and Quantitative Analyses.

    ERIC Educational Resources Information Center

    Loh, Stanley; De Oliveira, Jose Palazzo M.; Gastal, Fabio Leite

    2001-01-01

    Presents an application of knowledge discovery in texts (KDT) concerning medical records of a psychiatric hospital. The approach helps physicians to extract knowledge about patients and diseases that may be used for epidemiological studies, for training professionals, and to support physicians to diagnose and evaluate diseases. (Author/AEF)

  20. Africa and International Policy Making for Lifelong Learning: Textual Revelations

    ERIC Educational Resources Information Center

    Preece, Julia

    2013-01-01

    This paper discusses the relationship between international agendas for lifelong learning and financial aid for low income countries, especially those on the African continent. It argues that there are subtle differences in terminology written by policymakers respectively in Europe and South Africa for lifelong learning but that international…

  1. Lifeworld and Textualism: Reassembling the Researcher/ed and "Others"

    ERIC Educational Resources Information Center

    Payne, Phillip G.

    2005-01-01

    This response to McKenzie's "post-post" concerns about environmental education research draws upon empirical, conceptual, anecdotal, metaphorical, imaged and poetic means to help the researcher "reassemble" the researcher/ed by attending to her/his relational body and embodiment of various, often hegemonic, socially constructed environmental…

  2. On Becoming Textually Active at Youthline, New Zealand

    ERIC Educational Resources Information Center

    Haxell, Ailsa Janet

    2015-01-01

    The phones hardly ring at Youthline New Zealand anymore; youth still have problems and seek help, but it mostly happens silently. This article reports on experiences of texting at a 24-hour crisis helpline for young people. To date, there has been no formal evidence base for this practice; however, for new practice, there never is. In prompting

  3. Lifeworld and Textualism: Reassembling the Researcher/ed and "Others"

    ERIC Educational Resources Information Center

    Payne, Phillip G.

    2005-01-01

    This response to McKenzie's "post-post" concerns about environmental education research draws upon empirical, conceptual, anecdotal, metaphorical, imaged and poetic means to help the researcher "reassemble" the researcher/ed by attending to her/his relational body and embodiment of various, often hegemonic, socially constructed environmental

  4. Textual inference for eligibility criteria resolution in clinical trials.

    PubMed

    Shivade, Chaitanya; Hebert, Courtney; Lopetegui, Marcelo; de Marneffe, Marie-Catherine; Fosler-Lussier, Eric; Lai, Albert M

    2015-12-01

    Clinical trials are essential for determining whether new interventions are effective. In order to determine the eligibility of patients to enroll into these trials, clinical trial coordinators often perform a manual review of clinical notes in the electronic health record of patients. This is a very time-consuming and exhausting task. Efforts in this process can be expedited if these coordinators are directed toward specific parts of the text that are relevant for eligibility determination. In this study, we describe the creation of a dataset that can be used to evaluate automated methods capable of identifying sentences in a note that are relevant for screening a patient's eligibility in clinical trials. Using this dataset, we also present results for four simple methods in natural language processing that can be used to automate this task. We found that this is a challenging task (maximum F-score=26.25), but it is a promising direction for further research. PMID:26376462

  5. On Becoming Textually Active at Youthline, New Zealand

    ERIC Educational Resources Information Center

    Haxell, Ailsa Janet

    2015-01-01

    The phones hardly ring at Youthline New Zealand anymore; youth still have problems and seek help, but it mostly happens silently. This article reports on experiences of texting at a 24-hour crisis helpline for young people. To date, there has been no formal evidence base for this practice; however, for new practice, there never is. In prompting…

  6. "Wrighting" the Self: New Technologies and Textual Subjectivities

    ERIC Educational Resources Information Center

    Sakr, Mona

    2012-01-01

    The expression of the self through multimodal texts is a central theme in education. While it has been suggested that new technologies act as important mediators in the relationship between texts and subjectivity, the mechanisms underlying such mediation has been a neglected topic of research. This paper considers the theoretical assumptions upon…

  7. Cockpit data link displays - An evaluation of textual formats

    NASA Technical Reports Server (NTRS)

    Mcgann, Alison; Lozito, Sandra; Corker, Kevin

    1992-01-01

    Data link technologies are being investigated for air/ground information transfer for commercial aircraft operation. This study was designed to measure which of four alpha-numeric display formats for display of data link information would lead to the quickest and most accurate memory retrieval in a part-task simulation environment. Pilots viewed a clearance for 10-15 seconds and were subsequently queried about the content of that clearance. Speed and accuracy of responses were measured across three retention tasks. The three retention tasks included free recall of a particular clearance. recognition of a previous clearance, and the comparison of element values between a previously displayed and current clearance. Each format was tested with and without a distraction task. Subjective ratings of each format were also collected. The analyses revealed no significant differences for reaction time or accuracy among the four formats. Explanations for these results as well as alternative methodologies are discussed.

  8. "Wrighting" the Self: New Technologies and Textual Subjectivities

    ERIC Educational Resources Information Center

    Sakr, Mona

    2012-01-01

    The expression of the self through multimodal texts is a central theme in education. While it has been suggested that new technologies act as important mediators in the relationship between texts and subjectivity, the mechanisms underlying such mediation has been a neglected topic of research. This paper considers the theoretical assumptions upon

  9. Digital Literacies in Higher Education: Exploring Textual and Technological Practice

    ERIC Educational Resources Information Center

    Lea, Mary R.; Jones, Sylvia

    2011-01-01

    Concerns are frequently raised about undergraduates being so immersed in web-based technologies in their broader lives that they have difficulties engaging in more conventional study practices, such as academic reading and writing essays. The research reported on here examines this issue through a literacies lens. The project findings illustrate…

  10. ZAP70 Expression Within del6q21, del11q13 and del17p13 Cytogenetic Subgroups of Iranian Patients with Chronic Lymphocytic Leukemia

    PubMed Central

    Jafari Ghahfarokhi, Hamideh; Ashoori, Saeede; Akbari, Mohamad Taghi; Lotfizadeh, Masoud; Karimi, Ali; Teimori, Hossein

    2014-01-01

    Background: B-cell chronic lymphocytic leukemia (B-CLL) is the most common form of leukemia in adults. Some reports showed that expression of ZAP70 gene and chromosomal abnormality are two prognostic factors in management of B-CLL Objectives: In this study, we determined ZAP70 mRNA expression level in the del17p13, del6q21 and del11q13 subgroups of Iranian B-CLL patients to investigate prognostic value of ZAP70 expression. Patients and Methods: In this cross-sectional study, fluorescence in situ hybridization analysis was carried out on 66 Iranian B-CLL patients. Zap70 mRNA expression was evaluated by using Real Time RT-PCR. Results: Molecular analysis showed that ZAP70 expression increased 2.46 fold in the del11q13 subgroup, 2.87 fold in the del17p13 and 1.87 fold in the del6q21, compared to the 15 patients in the control group. Comparison of standard deviation and mean of the ZAP70 expression profile within the subgroups showed more variability among the cases of the del11q13 and del17p13 versus tight clustering for the del6q21. Therefore, there is a relation between del6q21 aberrations; which has good prognosis with normal levels of ZAP70 expression. Conclusions: The results of ANOVA test showed that ZAP70 expression gene was significantly increased in del17p13 and del11q13 subgroups compared to control group. Thus, ZAP70 may play an important role in the prognosis of B-CLL patients. PMID:25763225

  11. Del Norte means north to recycling

    SciTech Connect

    Aquino, J.T.

    1998-06-01

    Del Norte Regional Recycling and Transfer Station is owned by the city of Oxnard, California and operated by BLT Enterprises, Inc. The Del Norte facility--located in southwestern Ventura County about an hour northwest of Los Angeles--processes polyethylene terephthalate (PET) and high-density polyethylene (HDPE) plastic containers, aluminum, steel, glass, old corrugated containers (OCC), newspapers, computer printout paper, white and colored ledger paper, coated book, supermix paper, telephone books, and old magazines. According to the company, there has been virtually no community opposition to the site. The facility has few neighbors, and those are agricultural. To keep the community relationship strong, the facility`s design and location all but eliminated odor and noise complaints. The building was designed against the prevailing wind pattern, and BLT processes odorous material fast. A misting system installed for dust suppression also can be used with a solution for odor control should the need arise.

  12. Procesamiento Digital de Imagenes del Cometa Halley

    NASA Astrophysics Data System (ADS)

    Ferrin, L.; Fuenmayor, F.; Naranjo, O.; Bulka, P.; Mendoza, C.

    1987-05-01

    Se reportan observaciones fotográficas del cometa Halley, obtenidas con los telescopios Schmidt de 1-m del CIDA, y de 35 cms de la ULA. Se hicieron exposiciones desde 2 segundos a 30 minutos y se utilizaron emulsiones IIa-O, 103a-F, y 103a-D, guladas manualmente 0 automaticámente. Las imágenes fueron digitalizadas con el microdensitómetro PDS, y procesadas con el sistema HACIENDA del CCIBM. Se experimentó con la Transformada de Fourier en dos dimensiones, y con la aplicación de filtros de paso alto y bajo. Se encontró que el metodo de "autocorrelación" es el mejor para separar "la vegetación" de "la montaña". Se aplicaron diversas técnicas a fin de cubrir ambos extremos: a) enfatizar detalles débiles en la cola, y b) penetrar en las regiones más intensas de la coma. Se lograron ambos objetivos. Detalles en la cola permitieron determinar velocidades de propagación de unos 50 a 90 kms/ seg. Se pudieron detectar no menos de tres perturbaciones en "Y", y una en 5? Co de Cisne). Se cree que las primeras están asociadas a eventos de desconexión. Se puede separar la cola de gas de la de polvo. Las fotos de color permiten enfatizar diferentes regiones espectrales con mayor claridad aún. El "balance" del color puede ser hecho con la computadora.

  13. Morphology, geology and geochemistry of the "Salar del Gran Bajo del Gualicho" (Rio Negro, Argentina)

    USGS Publications Warehouse

    Angelucci, A.; Barbieri, M.; Brodtkorb, A.; Ciccacci, S.; Civitelli, G.; De Barrio, R.; Di, Filippo M.; Fredi, P.; Friedman, I.; Lombardi, S.; Schalamuk, A.I.; Toro, B.

    1996-01-01

    A multidisciplinary study of the Gran Bajo del Gualicho area (Rio Negro - Argentina) was carried out; the aim was to delineate its geological and geomorphological evolution and to estabilish the genesis of salts filling the depression. Climatic conditions were analized first to individuate their role in the present morphogenetic processes; moreover the main morphological features of present landscape were examined as well as the stratigraphy of the outcropping formations, and of the Gran Bajo del Gualicho Formation in particular. Finally, a possible geomorphological evolution of the studied area was traced. Geophysical analyses allowed to estabilish that the paleosurface shaped on the crystalline basement is strongly uneven and shows evidence of the strong tectonic phases it underwent. The result of isotope analyses confirmed that the salt deposits on the Gran Bajo del Gualicho bottom were produced by fresh water evaporation, while strontium isotope ratio suggested that such waters were responsible for solubilization of more ancient evaporitic deposits.

  14. Del-1 overexpression potentiates lung cancer cell proliferation and invasion.

    PubMed

    Lee, Seung-Hwan; Kim, Dong-Young; Jing, Feifeng; Kim, Hyesoon; Yun, Chae-Ok; Han, Deok-Jong; Choi, Eun Young

    Developmental endothelial locus-1 (Del-1) is an endogenous anti-inflammatory molecule that is highly expressed in the lung and the brain and limits leukocyte migration to these tissues. We previously reported that the expression of Del-1 is positively regulated by p53 in lung endothelial cells. Although several reports have implicated the altered expression of Del-1 gene in cancer patients, little is known about its role in tumor cells. We here investigated the effect of Del-1 on the features of human lung carcinoma cells. Del-1 mRNA was found to be significantly decreased in the human lung adenocarcinoma cell lines A549 (containing wild type of p53), H1299 (null for p53) and EKVX (mutant p53), compared to in human normal lung epithelial BEAS-2B cells and MRC-5 fibroblasts. The decrease of Del-1 expression was dependent on the p53 activity in the cell lines, but not on the expression of p53. Neither treatment with recombinant human Del-1 protein nor the introduction of adenovirus expressing Del-1 altered the expression of the apoptosis regulators BAX, PUMA and Bcl-2. Unexpectedly, the adenovirus-mediated overexpression of Del-1 gene into the lung carcinoma cell lines promoted proliferation and invasion of the lung carcinoma cells, as revealed by BrdU incorporation and transwell invasion assays, respectively. In addition, overexpression of the Del-1 gene enhanced features of epithelial-mesenchymal transition (EMT), such as increasing vimentin while decreasing E-cadherin in A549 cells, and increases in the level of Slug, an EMT-associated transcription regulator. Our findings demonstrated for the first time that there are deleterious effects of high levels of Del-1 in lung carcinoma cells, and suggest that Del-1 may be used as a diagnostic or prognostic marker for cancer progression, and as a novel therapeutic target for lung carcinoma. PMID:26545781

  15. Huave de San Mateo del Mar, Oaxaca (Huave of San Mateo del Mar, Oaxaca).

    ERIC Educational Resources Information Center

    Mexico Coll. (Mexico City)

    This document is one of 17 volumes on indigenous Mexican languages and is the result of a project undertaken by the Archivo de Lenguas Indigenas de Mexico. This volume contains information on Huave, an indigenous language of Mexico spoken in San Mateo del Mar, in the state of Oaxaca. The objective of collecting such a representative sampling of…

  16. Near Infrared Photometry of Nova Del 2013

    NASA Astrophysics Data System (ADS)

    Cass, C. A.; Carlon, L. R.; Corgan, T. D.; Dykhoff, A. D.; Gehrz, D. R.; Shenoy, P. D.

    2013-08-01

    Subjects: Infra-Red, Nova We report RIJHKLM photometry of Nova Del 2013 taken on August 28.13 UT using an As:Si bolometer mounted on the 0.76-m infrared telescope of the University of Minnesota's O'Brien Observatory (Marine on St. Croix, Minnesota, USA). Vega (alpha Lyrae) was used as the standard star. On this date we find: R = 5.6 +/- 0.1, I = 5.2 +/- 0.1, J = 4.5 +/- 0.1, H = 4.7 +/- 0.1, K = 4.7 +/- 0.1, L = 3.3 +/- 0.2, M = +1.8 +/- 0.3.

  17. Se evitaron casi 800 000 muertes por descenso del tabaquismo

    Cancer.gov

    Programas y estrategias de control del tabaco del siglo XX fueron responsables de la prevencin de ms de 795 000 muertes por cncer de pulmn en Estados Unidos de 1975 al 2000. Si todo el tabaquismo en este pas hubiera cesado despus de la publicacin d

  18. 33 CFR 110.65 - Indian River Bay, Del.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Indian River Bay, Del. 110.65... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.65 Indian River Bay, Del. Beginning at a point bearing... State highway bridge across Indian River Inlet; thence 174°, 600 feet; thence 264°, 800 feet; thence...

  19. 33 CFR 110.65 - Indian River Bay, Del.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Indian River Bay, Del. 110.65... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.65 Indian River Bay, Del. Beginning at a point bearing... State highway bridge across Indian River Inlet; thence 174°, 600 feet; thence 264°, 800 feet; thence...

  20. 33 CFR 110.65 - Indian River Bay, Del.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Indian River Bay, Del. 110.65... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.65 Indian River Bay, Del. Beginning at a point bearing... State highway bridge across Indian River Inlet; thence 174°, 600 feet; thence 264°, 800 feet; thence...

  1. 33 CFR 110.65 - Indian River Bay, Del.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Indian River Bay, Del. 110.65... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.65 Indian River Bay, Del. Beginning at a point bearing... State highway bridge across Indian River Inlet; thence 174°, 600 feet; thence 264°, 800 feet; thence...

  2. 33 CFR 110.65 - Indian River Bay, Del.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Indian River Bay, Del. 110.65... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.65 Indian River Bay, Del. Beginning at a point bearing... State highway bridge across Indian River Inlet; thence 174°, 600 feet; thence 264°, 800 feet; thence...

  3. Pastoral del Nino: Bringing the Abundant Life to Paraguayan Children

    ERIC Educational Resources Information Center

    Austin, Ann Berghout; Aquino, Cyle; Burro, Elizabeth

    2007-01-01

    Pastoral del Nino is transforming children's lives in rural Paraguay. Part of Pastoral Social (Catholic Social Services), Pastoral del Nino's primary focus is to bring "vida en abundancia" (the abundant life) to families by ensuring that mothers survive childbirth and children reach their first birthdays. In addition, the organization promotes…

  4. 33 CFR 80.1118 - Marina Del Rey, CA.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Marina Del Rey, CA. 80.1118 Section 80.1118 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Coast § 80.1118 Marina Del Rey, CA. (a) A line drawn...

  5. 75 FR 78966 - Del Norte Resource Advisory Committee (RAC)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ... Forest Service Del Norte Resource Advisory Committee (RAC) AGENCY: Forest Service, USDA. ACTION: Notice... Del Norte County Unified School District, Redwood Room, 301 West Washington Boulevard, Crescent City... Forest, at (707) 441-3569; e-mail adellinger@fs.fed.us . SUPPLEMENTARY INFORMATION: The meeting is...

  6. 76 FR 13124 - Del Norte Resource Advisory Committee (RAC)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-10

    ... Forest Service Del Norte Resource Advisory Committee (RAC) AGENCY: Forest Service, USDA. ACTION: Notice... Norte County Unified School District, Redwood Room 301, West Washington Boulevard, Crescent City... National Forest, at (707) 441-3569; e-mail adellinger@fs.fed.us . SUPPLEMENTARY INFORMATION: The Del...

  7. 77 FR 50080 - Del Norte County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-20

    ... Forest Service Del Norte County Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice... recommendations to the Forest Service concerning projects and funding consistent with the title II of the Act. The... at the Del Norte County Unified School District, Redwood Room, 301 West Washington...

  8. 76 FR 8333 - Del Norte Resource Advisory Committee (RAC)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-14

    ... Forest Service Del Norte Resource Advisory Committee (RAC) AGENCY: Forest Service, USDA. ACTION: Notice... at the Del Norte County Unified School District, Redwood Room, 301 West Washington Boulevard..., Six Rivers National Forest, at (707) 441-3569; e-mail adellinger@fs.fed.us . SUPPLEMENTARY...

  9. 75 FR 63437 - Del Norte Resource Advisory Committee (RAC)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... Forest Service Del Norte Resource Advisory Committee (RAC) AGENCY: Forest Service, USDA. ACTION: Notice... Del Norte County Unified School District, Redwood Room, 301 West Washington Boulevard, Crescent City... Forest, at (707) 441-3673; e-mail: jranieri@fs.fed.us . SUPPLEMENTARY INFORMATION: The meeting is open...

  10. 33 CFR 110.111 - Marina del Rey Harbor, Calif.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Marina del Rey Harbor, Calif. 110.111 Section 110.111 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.111 Marina del Rey Harbor, Calif. An area...

  11. The lightcone of Gödel-like spacetimes

    NASA Astrophysics Data System (ADS)

    Dautcourt, G.

    2010-11-01

    A study of the lightcone of the Gödel universe is extended to the so-called Gödel-like spacetimes. This family of highly symmetric 4D Lorentzian spaces is defined by metrics of the form ds^2=-(dt+H(x)\\,dy)^2+D^2(x)\\,dy^2+dx^2+\\\\dz^2, together with the requirement of spacetime homogeneity, and includes the Gödel metric. The quasi-periodic refocussing of cone generators with startling lens properties, discovered by Ozsváth and Schücking for the lightcone of a plane gravitational wave and also found in the Gödel universe, is a feature of the whole Gödel family. We discuss geometrical properties of caustics and show that (a) the focal surfaces are two-dimensional null surfaces generated by non-geodesic null curves and (b) intrinsic differential invariants of the cone attain finite values at caustic subsets.

  12. Illuminating water and life: Emilio Del Giudice.

    PubMed

    Ho, Mae-Wan

    2015-01-01

    The quantum electrodynamics theory of water put forward by Del Giudice and colleagues provides a useful foundation for a new science of water for life. The interaction of light with liquid water generates quantum coherent domains in which the water molecules oscillate between the ground state and an excited state close to the ionizing potential of water. This produces a plasma of almost free electrons favoring redox reactions, the basis of energy metabolism in living organisms. Coherent domains stabilized by surfaces, such as membranes and macromolecules, provide the excited interfacial water that enables photosynthesis to take place, on which most of life on Earth depends. Excited water is the source of superconducting protons for rapid intercommunication within the body. Coherent domains can also trap electromagnetic frequencies from the environment to orchestrate and activate specific biochemical reactions through resonance, a mechanism for the most precise regulation of gene function. PMID:26098522

  13. Wave maps from Gödel's universe

    NASA Astrophysics Data System (ADS)

    Barletta, Elisabetta; Dragomir, Sorin; Magliaro, Marco

    2014-10-01

    Using a result by Koch (1988 Trans. Am. Math. Soc. 307 827-41) we realize Gödel's universe G_{α }^{4}=({{{R}}^{4}},{{g}_{α}}) as the total space of a principal {R}-bundle over a strictly pseudo-convex CR manifold M3 and exploit the analogy between {{g}_{Yalpha;}} and Fefferman's metric {{F}_{θ}} (Fefferman 1976 Ann. Math. 103 395-416 104 393-4) to show that for any {R}-invariant wave map Φ of G_{α}^{4} into a Riemannian manifold N, the corresponding base map φ :{{M}^{3}}\\to N is subelliptic harmonic, with respect to a canonical choice of contact form θ on M3. We show that the subelliptic Jacobi operator J_{b}^{φ} of ϕ has a discrete Dirichlet spectrum on any bounded domain D\\subset {{M}^{3}} supporting the Poincaré inequality on \\mathop{W}\\limits^{\\circ }{}_{H}^{1,2}(D,{{φ}^{-1}}TN) and Kondrakov compactness, i.e. compactness of the embedding \\mathop{W}\\limits^{\\circ }{}_{H}^{1,2}(D,{{φ }^{-1}}TN)\\hookrightarrow {{L}^{2}}(D,{{φ}^{-1}}TN). We exhibit an explicit solution π :G_{α}^{4}\\to {{M}^{3}} to the wave map system on G_{α}^{4}, of index in{{d}^{Ω}}(π)\\geqslant 1 for any bounded domain Ω \\subset G_{α}^{4}. Mounoud's distance (Mounoud 2001 Differ. Geom. Appl. 15 47-57) d_{{{G}_{0}}, Ω }^{∞}({{g}_{α }}, {{F}_{θ}}) is bounded below by a constant depending only on the rotation frequency of Gödel's universe, thus giving a measure of the bias of {{g}_{α}} from being Fefferman like in the region Ω \\subset {{{R}}^{4}}.

  14. Características del viento en estrellas Be derivadas del perfil Hα

    NASA Astrophysics Data System (ADS)

    Rohrmann, R.; Cidale, L.

    El estudio teórico de perfiles Hα y su variabilidad en estrellas Be ha sido frecuentemente desarrollado en base a modelos de envolturas circunestelares inhomogéneas, donde la geometría del material es responsable de la forma del perfil dependiendo de la dirección de observación. Nosotros damos una interpretación alternativa y proponemos que la mayoría de las propiedades de esta línea tienen origen en la base de un viento estelar y de una estructura cromosférica anexa a la fotósfera. Encontramos que típicos perfiles Hα en Be, como son los llamados pole-on y winebottle, pueden ser reproducidos cualitativamente sin recurrir a la existencia de una envoltura asimétrica. Analizamos como la línea Hα permite identificar la posible estructura del viento en la región donde éste se inicia.

  15. Estudio teórico del CO2. Orbitales de valencia y del ``core''

    NASA Astrophysics Data System (ADS)

    Olalla Gutiérrez, E.

    Hemos calculado las intensidades de las transiciones E1 a los miembros de las series de Rydberg con origen en los orbitales ``no enlazantes'' del dióxido de carbono, especie de conocida relevancia atmosférica. Se han computado, asimismo, los continuos de fotoionización correspondientes a los distintos canales de ionización, representándolos como densidad espectral de fuerza de oscilador frente a la energía del fotón incidente; mostramos los resultados df/dE para la fotoionización total de esta especie en el intervalo 15-60 eV. Todos los cálculos se han llevado a cabo mediante la formulación Molecular del Método de los Orbitales de Defecto Cuántico, MQDO [1,2]. La calidad de los resultados que presentamos se ha evaluado en base a la comparación con los datos, tanto experimentales como teóricos, disponibles en la bibliografía. El acuerdo encontrado es altamente satisfactorio

  16. 34. VIEW OF DEL PASO ROAD NEAR INTERSECTION WITH POWERLINE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    34. VIEW OF DEL PASO ROAD NEAR INTERSECTION WITH POWERLINE ROAD, FACING EAST. - Reclamation District 1000, Northwest Sacramento County & southwest Sutter County, bisected by State Highway No. 99, Sacramento, Sacramento County, CA

  17. 26. VIEW OF SMALL DITCH FROM DEL PASO ROAD, FACING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. VIEW OF SMALL DITCH FROM DEL PASO ROAD, FACING NORTH. - Reclamation District 1000, Northwest Sacramento County & southwest Sutter County, bisected by State Highway No. 99, Sacramento, Sacramento County, CA

  18. Centro para la Salud Mundial (CGH) del NCI

    Cancer.gov

    El Centro para la Salud Mundial (CGH) del NCI coordina actividades de investigación y trabaja con socios nacionales e internacionales para comprender y enfrentar la carga que representa el cáncer a nivel mundial.

  19. Living Legacy: A Conversation with Carolina Gomez del Valle.

    ERIC Educational Resources Information Center

    Montessori Life, 1993

    1993-01-01

    Carolina Gomez del Valle has been involved in training other Montessorians in Mexico, Chile, Nicaragua, Peru, and Taiwan. This interview explores her experiences with Montessori education and describes how she has woven her religious training and Montessori philosophy together. (PAM)

  20. 65. Photographer unknown March 1931 DEL NORTE COUNTY, SECTION B, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    65. Photographer unknown March 1931 DEL NORTE COUNTY, SECTION B, HIGHWAY 1, 1-DN-1-B #66A, STA. 166.0+00 WIDENED ROADBED BEFORE COVERING LOG CRIB, 3-31. BACK READS: WIDENING ROAD BED WITH LOGS, APPROX 30 SQUARE & 60 LONG ON DN-1 SEC B STA 156+. Stamped office copy, - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  1. Se evitaron casi 800 000 muertes por descenso del tabaquismo

    Cancer.gov

    Programas y estrategias de control del tabaco del siglo XX fueron responsables de la prevención de más de 795 000 muertes por cáncer de pulmón en Estados Unidos de 1975 al 2000. Si todo el tabaquismo en este país hubiera cesado después de la publicación d

  2. Estudio del sistema simbiótico AR Pavonis

    NASA Astrophysics Data System (ADS)

    Quiroga, C.; Brandi, E.; Ferrer, O.; García, L.; Barbá, R.

    Se presenta un estudio espectroscópico y polarimétrico de la binaria eclipsante AR Pavonis a partir de observaciones obtenidas con el telescopio de 2.15 m. del CASLEO (San Juan). El estudio de la naturaleza del sistema se realizó a través del análisis de algunos espectros reunidos entre los años 1990 y 1995 y de datos polarimétricos correspondientes al intervalo 1995 y 1997. El análisis espectroscópico indica que AR Pav está compuesta por una gigante roja M3.7 y una componente caliente compacta, con una temperatura mayor a 90000 K y una luminosidad del orden de 500Lsolar. A lo largo del período orbital, las variaciones observadas en flujo y en velocidades radiales, reflejan que las emisiones permitidas se forman en una región que rodea la componente caliente. El estudio de la polarización lineal de AR Pav indica que además de una componente interestelar, existe una componente intrínseca del sistema que varía temporalmente y con la longitud de onda de la luz polarizada. El distinto comportamiento del grado de polarización y del ángulo de posición observado en fases diferentes, sugiere que distintos mecanismos pueden estar actuando, dependiendo de la región de scattering observado a lo largo de la línea de la visual.

  3. Investigação dos perfís temporais de alta resolução de explosões solares tipo-III decimétricas

    NASA Astrophysics Data System (ADS)

    Cecatto, J. R.; Fernandes, F. C. R.; Sawant, H. S.; Madsen, F. R. H.

    2003-08-01

    Explosões solares tipo-III indicam a presença de feixes de elétrons acelerados durante "flares" solares. Sua investigação fornece informações tanto sobre os processos de aceleração de partículas quanto das características do agente causador e do local de aceleração. Explosões tipo-III decimétricas são geradas por feixes de elétrons viajando através de arcos magnéticos densos da baixa coroa solar. Os perfís temporais destes fenômenos, quando tomados com alta resolução, informam sobre os mecanismos de aceleração de partículas do feixe e o meio de transporte da energia liberada a partir da região de aceleração. Usando o Brazilian Solar Spectroscope (BSS), em operação no INPE, foram registradas dezenas de explosões tipo-III decimétricas, dentro da faixa de 2050-2250 MHz com alta resolução temporal (20 ms), em 13 de setembro de 2001, entre 13:00 e 16:10 UT. Foram selecionadas 10 explosões isoladas para uma investigação estatística detalhada de seus perfís temporais, em todos os cerca de 50 canais de freqüência. Os resultados indicam que cerca de 70% dos perfís temporais são complexos tanto durante a subida quanto descida. Os 30% restantes indicam que os perfís da subida podem ser bem representados, na maioria dos casos, por um processo não-linear e uma parcela significativa por processos lineares. Os perfís temporais da descida são dominados por um decaimento não-linear. Neste trabalho, será efetuada uma análise dos perfís temporais, tanto durante a subida quanto descida do fluxo, para as explosões selecionadas, em termos dos prováveis mecanismos de aceleração e relaxamento. 2

  4. Field measurements of del13C in ecosystem respiration

    NASA Astrophysics Data System (ADS)

    van Asperen, Hella; Sabbatini, Simone; Nicolini, Giacomo; Warneke, Thorsten; Papale, Dario; Notholt, Justus

    2014-05-01

    Stable carbon isotope del13C-measurements are extensively used to study ecological and biogeochemical processes in ecosystems. Above terrestrial ecosystems, atmospheric del13C can vary largely due to photosynthetic fractionation. Photosynthetic processes prefer the uptake of the lighter isotope 12C (in CO2), thereby enriching the atmosphere in 13C and depleting the ecosystem carbon. At night, when ecosystem respiratory fluxes are dominant, 13C-depleted CO2 is respired and thereby depletes the atmospheric del13C-content. Different ecosystems and different parts of one ecosystem (type of plant, leaves, and roots) fractionate and respire with a different del13C-ratio signature. By determining the del13C-signature of ecosystem respiration in temporal and spatial scale, an analysis can be made of the composition of respiratory sources of the ecosystem. A field study at a dry cropland after harvest (province of Viterbo, Lazio, Italy) was performed in the summer of 2013. A FTIR (Fourier Transform Infrared Spectrometer) was set up to continuously measure CO2-, CH4-, N2O-, CO- and del13C-concentrations. The FTIR was connected to 2 different flux measurements systems: a Flux Gradient system (sampling every half hour at 1.3m and 4.2m) and 2 flux chambers (measured every hour), providing a continuous data set of the biosphere-atmosphere gas fluxes and of the gas concentrations at different heights. Keeling plot intercept values of respiratory CO2, measured by the Flux Gradient system at night, were determined to be between -25‰ and -20‰. Keeling plot intercept values of respiratory CO2, measured by the flux chamber system, varied between -24‰ and -29‰, and showed a clear diurnal pattern, suggesting different (dominant) respiratory processes between day and night.

  5. Symmetries of geodesic motion in Gödel-type spacetimes

    SciTech Connect

    Camci, U.

    2014-07-01

    In this paper, we study Noether gauge symmetries of geodesic motion for geodesic Lagrangian of four classes of metrics of Gödel-type spacetimes for which we calculated the Noether gauge symmetries for all classes I-IV, and find the first integrals of corresponding classes to derive a complete characterization of the geodesic motion. Using the obtained expressions for t-dot , r-dot ,φ-dot and ż of each classes I-IV which depends essentially on two independent parameters m and w, we explicitly integrated the geodesic equations of motion for the corresponding Gödel-type spacetimes.

  6. Systemic Functional Linguistics and Discourse Analysis as Alternatives When Dealing with Texts (La lingüística sistémica funcional y el análisis del discurso como alternativas para trabajar con textos)

    ERIC Educational Resources Information Center

    García Montes, Paula Andrea; Sagre Barboza, Ana María; Lacharme Olascoaga, Alba Isabel

    2014-01-01

    This article presents a case study research with aims to find out which activities, methodological and textual aspects used in a reading strategies course were causing a group of students difficulties when analyzing critically written information. We conducted the study at Universidad de Córdoba (Colombia) with seventh semester students from the…

  7. Screening of 185DelAG, 1014DelGT and 3889DelAG BRCA1 mutations in breast cancer patients from North-East India.

    PubMed

    Hansa, Jagadish; Kannan, Ravi; Ghosh, Sankar Kumar

    2012-01-01

    Around 1.35 million people of worldwide suffer from breast cancer each year, whereas in India, 1 in every 17 women develops the disease. Mutations of the Breast Cancer 1 (BRCA1) gene account for the majority of breast/ ovarian cancer families. The purpose of study was to provide a prevalence of BRCA1 germline mutations in the North-East Indian population. In relation to the personal and family history with the breast cancer, we found mutations in 6.25% and 12.5% respectively. Three mutations, 185DelAG, 1014DelGT and 3889DelAG, were observed in our North-East Indian patients in exons 2 and 11, resulting in truncation of the BRCA1 protein by forming stop codons individually at amino acid positions 39, 303 and 1265. Our results point to a necessity for an extensive mutation screening study of high risk breast cancer cases in our North-East Indian population, which will provide better decisive medical and surgical preventive options. PMID:23317271

  8. Cirugía de los trastornos del comportamiento: el estado del arte

    PubMed Central

    Yampolsky, Claudio; Bendersky, Damián

    2014-01-01

    Introducción: La cirugía de los trastornos del comportamiento (CTC) se está convirtiendo en un tratamiento más común desde el desarrollo de la neuromodulación. Métodos: Este artículo es una revisión no sistemática de la historia, indicaciones actuales, técnicas y blancos quirúrgicos de la CTC. Dividimos su historia en 3 eras: la primera comienza en los inicios de la psicocirugía y termina con el desarrollo de las tícnicas estereotácticas, cuando comienza la segunda era. Ésta se caracteriza por la realización de lesiones estereotácticas. Nos encontramos transitando la tercera era, que comienza cuando la estimulación cerebral profunda (ECP) comienza a ser usada en CTC. Resultados: A pesar de los errores graves cometidos en el pasado, hoy en día, la CTC está renaciendo. Los trastornos psiquiátricos que se más frecuentemente se tratan con cirugía son: depresión refractaria, trastorno obsesivo-compulsivo y síndrome de Tourette. Además, algunos pacientes con agresividad fueron tratados quirúrgicamente. Hay varios blancos estereotácticos descriptos para estos trastornos. La estimulación vagal puede ser usada también para depresión. Conclusión: Los resultados de la ECP en estos trastornos parecen alentadores. Sin embargo, se necesitan más estudios randomizados para establecer la efectividad de la CTC. Debe tenerse en cuenta que una apropiada selección de pacientes nos ayudará a realizar un procedimiento más seguro así como también a lograr mejores resultados quirúrgicos, conduciendo a la CTC a ser más aceptada por psiquiatras, pacientes y sus familias. Se necesita mayor investigación en varios temas como: fisiopatología de los trastornos del comportamiento, indicaciones de CTC y nuevos blancos quirúrgicos. PMID:25165612

  9. Design, aerodynamics and autonomy of the DelFly.

    PubMed

    de Croon, G C H E; Groen, M A; De Wagter, C; Remes, B; Ruijsink, R; van Oudheusden, B W

    2012-06-01

    One of the major challenges in robotics is to develop a fly-like robot that can autonomously fly around in unknown environments. In this paper, we discuss the current state of the DelFly project, in which we follow a top-down approach to ever smaller and more autonomous ornithopters. The presented findings concerning the design, aerodynamics and autonomy of the DelFly illustrate some of the properties of the top-down approach, which allows the identification and resolution of issues that also play a role at smaller scales. A parametric variation of the wing stiffener layout produced a 5% more power-efficient wing. An experimental aerodynamic investigation revealed that this could be associated with an improved stiffness of the wing, while further providing evidence of the vortex development during the flap cycle. The presented experiments resulted in an improvement in the generated lift, allowing the inclusion of a yaw rate gyro, pressure sensor and microcontroller onboard the DelFly. The autonomy of the DelFly is expanded by achieving (1) an improved turning logic to obtain better vision-based obstacle avoidance performance in environments with varying texture and (2) successful onboard height control based on the pressure sensor. PMID:22617112

  10. Interdisciplinary Unit: La Isla del Encanto (The Enchanted Island).

    ERIC Educational Resources Information Center

    Ford-Guerrera, Rebecca

    This document presents a series of 14 lesson plans in an interdisciplinary Spanish unit on "La isla del encanto/The Enchanted Island." The materials were prepared for students in grades 5 or 6 who have had basic Spanish instruction in previous grades. The students should also be familiar with basic concepts in English such as math computation, map

  11. Síntesis: Resultados iniciales del Estudio Nacional de Ex

    Cancer.gov

    El 4 de noviembre de 2010, el Estudio Nacional de Exámenes de Pulmóndio a conocer resultados iniciales que indican que hubo 20% menos muertes por cáncer de pulmón entre los participantes del estudio evaluados con tomografía computarizada espiral de baja d

  12. Interdisciplinary Unit: La Isla del Encanto (The Enchanted Island).

    ERIC Educational Resources Information Center

    Ford-Guerrera, Rebecca

    This document presents a series of 14 lesson plans in an interdisciplinary Spanish unit on "La isla del encanto/The Enchanted Island." The materials were prepared for students in grades 5 or 6 who have had basic Spanish instruction in previous grades. The students should also be familiar with basic concepts in English such as math computation, map…

  13. 78 FR 50025 - Del Norte County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ... Forest Service Del Norte County Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice... collaborative relationships and to provide advice and recommendations to the Forest Service concerning projects..., contact: Lynn Wright, RAC Committee Coordinator, Six Rivers National Forest, 707-441-3562,...

  14. 77 FR 47360 - Del Norte Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-08

    ... Forest Service Del Norte Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of... recommendations to the Forest Service concerning projects and funding consistent with the title II of the Act. The... Unified School District, Redwood Room, 301 West Washington Boulevard, Crescent City CA 95531....

  15. 78 FR 30268 - Del Norte County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-22

    ... Forest Service Del Norte County Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice... recommendations to the Forest Service concerning projects and funding consistent with the title II of the Act. The... Norte County Unified School District, Redwood Room, 301 West Washington Boulevard, Crescent City...

  16. Faculty Activity Analysis in the Universidad Tecnica Del Estado Campuses.

    ERIC Educational Resources Information Center

    Karadima, Oscar

    An analysis of academic activities of college faculty at the eight campuses of Chile's Universidad Tecnica del Estado was conducted. Activities were grouped into seven categories: direct teaching, indirect teaching, research, community services, faculty development, academic administration, and other activities. Following the narrative…

  17. Cosmogenic Radionuclides in the Campo Del Cielo Iron Meteorite

    NASA Technical Reports Server (NTRS)

    Liberman, R. G.; FernandezNiello, J. O.; Reedy, R. C.; Fifield, L. K.; diTada, M. L.

    2001-01-01

    Cosmogenic Be-10, Al-26, Cl-36, Ca-41, and Ni-59 were measured in the Campo del Cielo iron meteorite. Our results led us to conclude that the pre-atmospheric radius might have been approximately 2 m. Comparisons with other big bodies are also presented. Additional information is contained in the original extended abstract.

  18. Molecular and cytogenetic characterization of del(9p) syndrome

    SciTech Connect

    Micale, M.A.; Haren, J.M.; Schwartz, S.

    1994-09-01

    The del(9p) syndrome is characterized by mental retardation, trigonocephaly, midface hypoplasia, upward slanting palpebral fissures, a long philtrum, and is typically associated with a breakpoint at 9p22. Seventeen unrelated patients with del(9p) and their parents were analyzed by high resolution chromosome studies, molecular analysis using a series of highly polymorphic dinucleotide repeat markers for 9p, and fluorescence in situ hybridization (FISH) to characterize precisely the extent of chromosome loss. Eleven patients were found to have an interstitial deletion with breakpoints assigned to 9p22.1 and 9p24.3 in most cases. Two patients had familial unbalanced translocations of maternal origin and four had de novo complex rearrangements identified by high resolution analysis and FISH utilizing chromosome libraries. PCR analysis of eleven families with eight minisatellite markers determined paternal origin of the deletion in six cases and maternal origin in five. This suggests that the molecular event resulting in the deletion is equally prevalent in both male and female gametogenesis and that genomic imprinting does not play a role in the pathogenesis of del(9p) syndrome. Increased precision in mapping these minisatellite markers was also possible through this work. This study demonstrates the existence of molecular heterogeneity as six patients with a cytological breakpoint at 9p22.1 revealed three different molecular breakpoints. These findings suggest that genotype-phenotype correlations in deletion syndromes such as this should be based on high-resolution molecular analysis of the deleted chromosome segment. Work is in progress to map a series of cosmid probes by FISH relative to chromosomal breakpoints in these patients. These combined studies should provide a better understanding of the mechanisms involved in the pathogenesis of del(9p) syndrome and may identify loci where genes responsible for one or more aspects of the del(9p) phenotype may reside.

  19. Extensión del Formalismo de Orbitales de Defecto Cuántico al tratamiento del efecto Stark (SQDO).

    NASA Astrophysics Data System (ADS)

    Menéndez, J. M.; Martín, I.; Velasco, A. M.

    El estudio experimental de las interacciones de átomos Rydberg altamente excitados con campos eléctricos ha experimentado un creciente interés durante las dos últimas décadas debido, en gran medida, al desarrollo de nuevas técnicas para crear y estudiar átomos Rydberg en el laboratorio. Acompañando a estas nuevas técnicas experimentales, es necesario el desarrollo de modelos teóricos que nos permitan contrastar sus medidas y conocer mejor los fundamentos de los mismos. Desde el punto de vista teórico el conocimiento del desdoblamiento de los niveles energéticos de un átomo en función de la magnitud del campo eléctrico aplicado (lo que se conoce como mapa Stark) es el mejor punto de partida para la descripción del sistema y un prerrequisito fundamental para el cálculo de distintas propiedades atómicas en presencia del campo eléctrico tales como intensidades de transición, umbrales de ionización de campo eléctrico, tiempos de vida, posición y anchura de cruces evitados, etc. En este trabajo presentamos la adaptación del método de orbitales de defecto cuántico [1,2,3] al tratamiento del efecto Stark (SQDO) [4] y su aplicación al cálculo de los desdoblamientos energéticos y fuerzas de oscilador de estados Rydberg en los átomos de Li, Na y K. El propósito de este estudio es, por un lado, desarrollar métodos fiables para la determinación de propiedades atómicas en presencia de campos eléctricos y, por otro, mostrar la fiabilidad de las funciones de onda QDO en la descripción del efecto Stark en sistemas atómicos.

  20. Preguntas para hacerle al doctor acerca del cáncer

    Cancer.gov

    Serie de preguntas, organizadas por tema, que los pacientes con cáncer pueden hacer al médico o a otros miembros de su equipo de atención médica para conocer más acerca de su tipo de cáncer y lo que pueden esperar.

  1. Analisis del contenido curricular de los Documentos Normativos del Programa de Ciencias en el area de biologia para la escuela superior del sistema de educacion publica de Puerto Rico: 1993-2012

    NASA Astrophysics Data System (ADS)

    Davila Montanez, Melissa

    Esta investigacion de naturaleza cualitativa se ocupo de realizar un analisis de contenido documental de los Documentos Normativos del Programa de Ciencias en el area de biologia de la escuela superior del sistema de educacion publica de Puerto Rico del periodo 1993-2012. Los documentos analizados fueron: Guia Curricular, 1995; Marco Curricular, 2003; Estandares de Excelencia, 1996, 2000 y Estandares de Contenido y Expectativas de Grado, 2007. Se indago si hubo cambios en significados en los Componentes Estructurales: Naturaleza de la ciencia, Paradigmas para la ensenanza de la ciencia, Funcion del curriculo formal, Mision de la ensenanza de la ciencia; Contenidos, destrezas y competencias, Estrategias de ensenanza y Evaluacion/Assessment del aprendizaje. El analisis sugiere que no hubo cambios sustanciales en los significados de los Componentes Estructurales. Los documentos estudiados muestran mayormente caracteristicas similares, aunque los documentos mas recientes eran mas descriptivos, explicativos y especificos.

  2. Genomic Copy Number Variations in the Myelodysplastic Syndrome and Acute Myeloid Leukemia Patients with del(5q) and/or -7/del(7q)

    PubMed Central

    Zhang, Rui; Kim, Young-Mi; Wang, Xianfu; Li, Yan; Lu, Xianglan; Sternenberger, Andrea R.; Li, Shibo; Lee, Ji-Yun

    2015-01-01

    The most common chromosomal abnormalities in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) are -5/del(5q) and -7/del(7q). When -5/del(5q) and -7/del(7q) coexist in patients, a poor prognosis is typically associated. Given that -5/del(5q) and/or -7/del(7q) often are accompanied with additional recurrent chromosomal alterations, genetic change(s) on the accompanying chromosome(s) other than chromosomes 5 and 7 may be important factor(s) affecting leukemogenesis and disease prognosis. Using an integrated analysis of karyotype, FISH and array CGH results in this study, we evaluated the smallest region of overlap (SRO) of chromosomes 5 and 7 as well as copy number alterations (CNAs) on the other chromosomes. Moreover, the relationship between the CNAs and del(5q) and -7/del(7q) was investigated by categorizing the cases into three groups based on the abnormalities of chromosomes 5 and 7 [group I: cases only with del(5q), group II: cases only with -7/del(7q) and group III: concurrent del(5q) and del(7q) cases]. The overlapping SRO of chromosome 5 from groups I and III was 5q31.1-33.1 and of chromosome 7 from groups II and III was 7q31.31-q36.1. A total of 318 CNAs were observed; ~ 78.3% of them were identified on chromosomes other than chromosomes 5 and 7, which were defined as 'other CNAs'. Group III was a distinctive group carrying the most high number (HN) CNAs, cryptic CNAs and 'other CNAs'. The loss of TP53 was highly associated with del(5q). The loss of ETV6 was specifically associated with group III. These CNAs or genes may play a secondary role in disease progression and should be further evaluated for their clinical significance and influence on therapeutic approaches in patients with MDS/AML carrying del(5q) and/or -7/del(7q) in large-scale, patient population study. PMID:26392809

  3. New records of fishes at Isla del Coco, Costa Rica

    USGS Publications Warehouse

    Garrison, V.H.

    1996-01-01

    Isla del Coco lies at 5 degrees 32'N latitude, 87 degrees 04'W longitude and is the sole peak of the Cocos Ridge exposed above sea level. This isolated island formed approximately 2 million years ago. It rises 575 m above the surface of the sea and covers 46 km2 (Castillo et aI., 1988). Five hundred km to the NNE is Costa Rica; 630 km SSW are the Galapagos Islands; 650 km to the E is Isla Malpelo, Colombia; and approximately 8,000 km W lie the Line Islands. Costa Rica claimed Isla del Coco in 1832 and declared it a National Park in 1978. The area of the park was increased to include the adjacent waters 5 km offshore in 1984 and 25 km offshore in 1991.

  4. Determinacion de Caracteristicas Opticas del Telescopio OAN150

    NASA Astrophysics Data System (ADS)

    Galan, M. J.; Cobos, F. J.

    1987-05-01

    En el Observatorio de Calar Alto, en Almería, España, está ubicado un telescopio de 15O-cms de diámetro -construído por REOSC- perteneciente al Observatorio Astronómico Nacional, con sede en Madrid, España. La infraestructura técnica del OAN ha sido tradicionalmente débil y actualmente se está haciendo un esfuerzo por fortalecerla. Existe una información muy limitada del telescopio en general; de su óptica en particular se conocían los valores de los parámetros principales pero sin saber si éstos corresponden a valores teóricos ó de construcción. Por ello se consideró necesario iniciar una investigación para conocer en detalle los valores reales de las componentes ópticas del telescopio, obteniéndose algunos resultados de interés. El primario del telescopio OANl5O es aproximadamente F/3 y el siste ma en su conjunto es F/8.2, con su sistema corrector de campo. En términos generales, la imagen es satisfactoria en todo el campo y, sin sistema corrector, la imagen axial también es buena. En un futuro muy cercano se piensa diseñar instrumentación adicional para este telescopio. Conocer con mayor precisión sus características puede ser de gran utilidad para tal fin, pues se efectúan los cálculos considerando conjuntamente al telescopio y al instrumento.

  5. 2. COURSE OF THE LATERAL THROUGH DEL NORTHWEST MAR PARK. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. COURSE OF THE LATERAL THROUGH DEL NORTHWEST MAR PARK. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

  6. 3. 1939 DROP STRUCTURE IN DEL MAR PARK SURMOUNTED BY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. 1939 DROP STRUCTURE IN DEL MAR PARK SURMOUNTED BY RECENT PEDESTRIAN BRIDGE. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

  7. Solar adaptive optics at the Observatorio del Teide, Tenerife

    NASA Astrophysics Data System (ADS)

    Soltau, Dirk; Berkefeld, Thomas; Schmidt, Dirk; von der Lühe, Oskar

    2013-10-01

    Observing the Sun with high angular resolution is difficult because the turbulence in the atmosphere is strongest during day time. In this paper we describe the principles of solar adaptive optics exemplified by the two German solar telescopes VTT and GREGOR at the Observatorio del Teide. With theses systems we obtain near diffraction limited images of the Sun. Ways to overcome the limits of conventional AO by applying multiconjugate adaptive optics (MCAO) are shown.

  8. Modeling Visibility in the EL Paso del Norte Region

    NASA Astrophysics Data System (ADS)

    Fitzgerald, R. M.; Medina, R.; DuBois, D. W.; Novlan, D.

    2013-12-01

    Poor visibility is a subject of growing public concern throughout the U.S, and an active area of research. Its societal impacts in air quality, aviation transport and traffic are significant. Aerosols play a fundamental role in the attenuation of solar radiation, and also affect visibility. The scattering and extinction coefficients of aerosol particles in the Paso del Norte Region have been calculated using the T- matrix model in conjunction with a laser particle counter. Inter-comparison of the model's results of the scattering and absorption coefficients against the corresponding data from a Photoacustic Extinctiometer instrument (which measures in-situ absorption and scattering coefficients of aerosol particles) shows excellent agreement. In addition, the volume-weighted method is used to determine the composite index of refraction which is representative of the aerosols for the Paso del Norte Airshed to obtain information of the type of aerosol particles present in the Airshed. The Single Scattering Albedo has also been retrieved using our methodology to obtain further insight into the type of aerosols present on a given day. Finally, the Koschmieder equation has been used to calculate the visual range or visibility, and was correlated with the PM2.5 and PM10 particle concentration present in the Airshed. Our methodology will allow a better understanding of the size and type of aerosol particles that are most detrimental to the visibility for the Paso del Norte Region.

  9. Modeling visibility in the Paso del Norte (PDN) Region

    NASA Astrophysics Data System (ADS)

    Medina Calderon, Richard

    Poor visibility is a subject of growing public concern throughout the U.S, and an active area of research. Its societal impacts on air quality, aviation transport and traffic are significant. Aerosols play a fundamental role in the attenuation of solar radiation, and also affect visibility. The scattering and extinction coefficients of aerosol particles in the Paso del Norte Region have been calculated using the T- matrix model in conjunction with a laser particle counter. Inter-comparison of the model's results of the scattering and absorption coefficients against the corresponding data from a Photoacustic extinctiometer instrument (which measures in-situ absorption and scattering coefficients of aerosol particles) shows excellent agreement. In addition, the volume-weighted method is used to determine the composite index of refraction which is representative of the aerosols for the Paso del Norte Region to obtain information of the type of aerosol particles present in the Region. The Single Scattering Albedo has also been retrieved using this methodology to obtain further insight into the type of aerosols present on a given day. Finally, the Koschmieder equation has been used to calculate the visual range or visibility, and was correlated with the PM2.5 and PM10 particle concentration present in the Region. Our methodology will allow a better understanding of the size and type of aerosol particles that are most detrimental to the visibility for the Paso Del Norte Region.

  10. Los plaguicidas y la contaminacion del medio ambiente Venezolano

    USGS Publications Warehouse

    Stickel, L.F.; Stickel, W.H.

    1972-01-01

    RESUMEN DE RECOMENDACIONES Recomendaciones para el Programa de Investigacion: 1. Establecer un sistema de muestreo biologico para detectar los niveles tendencias de los productos quimicos toxicos en un peque?o numero de si tios representativos. 2. Mantener continua vigilancia de la contaminacion ambiental, mediante la seleccion acertadamente dirigida de las zonas afectadas y de las fuentes de contaminacion. 3. Realizar estudios acerca de las poblaciones de animales silvestres, y del exito de los procesos reproductivos de las especies o grupos clayes de animales que se consideran mas gravemente afectados. 4. Preparar recomendaciones para una accion gubernamental de proteccion al hombre, a la fauna silvestre y al medio ambiente. Recomendaciones para la Accion Administrativa: 1. Establecer limites a la tolerancia de los residuos de plaguicidas en los alimentos. Constituye una medida clave para disminuir la contaminacion ambiental. 2. Establecer normas de calidad del agua para las corrientes, represas, la gos y otros cuerpos. Es la segunda medida clave para reducir la contaminacion del ambiente 3. Exigir un tratamiento adecuado de los efluentes industriales, especialmente antes de que se construyan las nuevas plantas. 4. Exigir a los agricultores que en el uso de plaguicidas sigan los consejos tecnicos autorizados y negar a los vendedores el derecho a recomendar productos por su cuenta. 5. Tomar medidas para recoger y eliminar los recipientes y sobrantes de los plaguicidas.

  11. Field Measurements of Respiratory Del13CO2 and Photodegradation

    NASA Astrophysics Data System (ADS)

    van Asperen, H.; Sabbatini, S.; Nicolini, G.; Warneke, T.; Papale, D.; Notholt, J.

    2014-12-01

    Carbon decomposition dynamics have been studied in a variety of ecosystems and its variation can mostly be explained in terms of environmental variables (e.g. temperature and precipitation). However, carbon dynamics in arid, water limited regions have shown to be very different and are still largely unknown. Several studies have indicated the importance of photodegradation, the direct breakdown of organic matter by sunlight, in these arid regions. A FTIR (Fourier Transform Infrared Spectrometer) was set up to continuously measure concentrations of CO2, CH4, N2O, CO as well as del13C in CO2. The FTIR was connected to 2 different flux measurement systems: a Flux Gradient system and 2 flux chambers, providing a continuous data set of gas concentrations and biosphere-atmosphere gas fluxes at different heights and scales. Field measurements showed photodegradation induced carbon fluxes. Also, respiratory del13CO2 was determined by use of Keeling plots, and was determined to vary between -25‰ and -21‰. A clear diurnal pattern in respiratory del13CO2 was found, suggesting either different (dominant) respiratory processes between day and night or the effect of diffusive fractionation.

  12. The 2012 Reactivation of Nevado del Ruiz Volcano, Colombia

    NASA Astrophysics Data System (ADS)

    Ordoñez, M.; Lopez, C.; Cortes, G. P.; Londoño, J.; Battaglia, M.

    2012-12-01

    Nevado Del Ruiz volcano is most known for its tragic November 13, 1985 explosive event, when a small eruption produced an enormous lahar that buried and destroyed the town of Armero in Tolima, causing an estimated 25,000 deaths. Similar but less deadly incidents occurred in 1595 and 1845, again where a small explosive eruption was followed by a large lahar. Other minor explosive events occurred in 1805, 1828-9, and 1989. The Armero tragedy was a major factor in the establishment of a volcano monitoring program in Colombia. The network monitoring Nevado del Ruiz volcano has dramatically improved since the 1985 eruption and now includes geodetic, geophysical, geochemical and visual monitoring. The activity of Nevado Del Ruiz between 1985 and 1991 saw significant increases in seismicity and significant gas emissions with the main eruptive events of November 13, 1985 and September 1st, 1989. The volcano became seismically active again in 1995 and 2002, whit an increase in seismicity, without any gas emission or eruption. In October 2010 the volcano entered in a new phase of unrest with increased seismicity (HB events), deformation and gas emissions, likely associated with a new magma intrusion. In February, 2012 the volcano had a new and significant increase in seismicity (VT-LP), followed in May and June 2012 by small phreatic and phreato-magmatic eruption. This eruptive activity is still ongoing. Deformation measurements at Nevado Del Ruiz volcano have been carried out since just after the tragic eruption of the 13th of November 1985. In 2007 seven new electronic tilt meters were set up to monitor the deformation. Significant uplift was measured from August 2007 to October 2010, for a total cumulative value of more than 500 microradians. From the end of 2011 to July 2012, moderate changes of uplift were detected for a total of 70 microradians. The analysis of these deformation data shows a pattern of surface displacement associated with an intrusion of new magma coming from a reservoir located approximately at a depth of approximately 8 km and accumulating in shallow reservoir less than 2 km beneath the main crater. We fit the data with both a spherical and a vertical spheroid source. The spherical source indicates the existence of an intrusion at a depth of 1823±1056 m with a volume change of (7±17)×106 m3 . The vertical spheroidal source suggests a source 1855 m deep with a volume change of 6×106 m3 . These results imply that while we have strong bounds on the depth of the intrusion, the actual volume of the source is less certain. Gas emission from Nevado del Ruiz volcano in April 7, 2012.

  13. Estrategia innovadora enfocada en parejas del mismo sexo para disminuir la infección del VIH en hombres Latinos

    PubMed Central

    Martinez, Omar; Wu, Elwin; Sandfort, Theo; Shultz, Andrew Z.; Capote, Jonathan; Chávez, Silvia; Moya, Eva; Dodge, Brian; Morales, Gabriel; Porras, Antonio; Ovejero, Hugo

    2014-01-01

    Resumen El VIH es un problema de salud importante dentro de la comunidad latina de los Estados Unidos. Gracias a los esfuerzos de prevención, los niveles de contagio entre los latinos se han mantenido estables por más de una década. Sin embargo, esta población sigue siendo afectada a niveles muy altos, en particular entre hombres que tienen sexo con hombres (HSH), de origen latino y que hablan principalmente el idioma español. Existen varios factores que contribuyen a la transmisión del VIH entre esta población, como son: el uso de drogas; la violencia dentro de la pareja; la presencia de infecciones de transmisión sexual; relaciones sexuales sin protección, dentro y fuera de la pareja; el evadir la búsqueda de recursos (prueba y tratamiento adecuado) por temor a ser discriminado o por su estatus migratorio; la escasez de recursos económicos o estado de pobreza y los patrones relacionados a la migración. En particular, Investigaciones Epidemiológicas de Comportamientos han determinado: cómo algunas dinámicas en parejas están directamente asociadas a los comportamientos sexuales de riesgos. En consecuencia, es necesaria mayor investigación para identificar esas dinámicas, y a su vez, realizar intervenciones dirigidas a la reducción de conductas de riesgo enfocadas en parejas de hombres del mismo sexo. En este escrito, se describe la importancia del uso de las relaciones de pareja como estrategia en la reducción de la trasmisión del VIH/SIDA en HSH de origen latino y que hablan principalmente el idioma español en los Estados Unidos. PMID:25580466

  14. Perk Ablation Ameliorates Myelination in S63del-Charcot-Marie-Tooth 1B Neuropathy.

    PubMed

    Musner, Nicolò; Sidoli, Mariapaola; Zambroni, Desireè; Del Carro, Ubaldo; Ungaro, Daniela; D'Antonio, Maurizio; Feltri, Maria L; Wrabetz, Lawrence

    2016-04-01

    In peripheral nerves, P0 glycoprotein accounts for more than 20% of myelin protein content. P0 is synthesized by Schwann cells, processed in the endoplasmic reticulum (ER) and enters the secretory pathway. However, the mutant P0 with S63 deleted (P0S63del) accumulates in the ER lumen and induces a demyelinating neuropathy in Charcot-Marie-Tooth disease type 1B (CMT1B)-S63del mice. Accumulation of P0S63del in the ER triggers a persistent unfolded protein response. Protein kinase RNA-like endoplasmic reticulum kinase (PERK) is an ER stress sensor that phosphorylates eukaryotic initiation factor 2 alpha (eIF2alpha) in order to attenuate protein synthesis. We have shown that increasing phosphophorylated-eIF2alpha (P-eIF2alpha) is a potent therapeutic strategy, improving myelination and motor function in S63del mice. Here, we explore the converse experiment:Perkhaploinsufficiency reduces P-eIF2alpha in S63del nerves as expected, but surprisingly, ameliorates, rather than worsens S63del neuropathy. Motor performance and myelin abnormalities improved in S63del//Perk+/- compared with S63del mice. These data suggest that mechanisms other than protein translation might be involved in CMT1B/S63del neuropathy. In addition,Perkdeficiency in other cells may contribute to demyelination in a non-Schwann-cell autonomous manner. PMID:27095827

  15. Perk Ablation Ameliorates Myelination in S63del-Charcot–Marie–Tooth 1B Neuropathy

    PubMed Central

    Musner, Nicolò; Sidoli, Mariapaola; Zambroni, Desireè; Del Carro, Ubaldo; Ungaro, Daniela; D’Antonio, Maurizio; Feltri, Maria L.

    2016-01-01

    In peripheral nerves, P0 glycoprotein accounts for more than 20% of myelin protein content. P0 is synthesized by Schwann cells, processed in the endoplasmic reticulum (ER) and enters the secretory pathway. However, the mutant P0 with S63 deleted (P0S63del) accumulates in the ER lumen and induces a demyelinating neuropathy in Charcot–Marie–Tooth disease type 1B (CMT1B)–S63del mice. Accumulation of P0S63del in the ER triggers a persistent unfolded protein response. Protein kinase RNA-like endoplasmic reticulum kinase (PERK) is an ER stress sensor that phosphorylates eukaryotic initiation factor 2 alpha (eIF2alpha) in order to attenuate protein synthesis. We have shown that increasing phosphophorylated-eIF2alpha (P-eIF2alpha) is a potent therapeutic strategy, improving myelination and motor function in S63del mice. Here, we explore the converse experiment: Perk haploinsufficiency reduces P-eIF2alpha in S63del nerves as expected, but surprisingly, ameliorates, rather than worsens S63del neuropathy. Motor performance and myelin abnormalities improved in S63del//Perk+/− compared with S63del mice. These data suggest that mechanisms other than protein translation might be involved in CMT1B/S63del neuropathy. In addition, Perk deficiency in other cells may contribute to demyelination in a non–Schwann-cell autonomous manner. PMID:27095827

  16. Screening for 185delAG in the Ashkenazim.

    PubMed Central

    Richards, C S; Ward, P A; Roa, B B; Friedman, L C; Boyd, A A; Kuenzli, G; Dunn, J K; Plon, S E

    1997-01-01

    A study was initiated to assess interest, educational effectiveness, and implications of genetic testing for the common BRCA1 mutation, 185delAG, in the Ashkenazim. Of 333 individuals who attended group sessions, 309 (92%) participated in the study. Participants were categorized as having negative family history (67%), positive family history (defined, by a relaxed criterion, as one first-degree relative or two second-degree relatives with breast [premenopausal] or ovarian cancer) (22%), positive personal history (7%), and both positive personal history and positive family history (4%). Group education was effective, as shown by the improvement in participant scores from pre- to posteducation tests. For the 289 individuals (94%) who requested testing, the major reasons included concern for their own risk, concern for the risk of their children, and desire to learn about surveillance options. The most common reason given by participants who declined testing was concern about health insurance. Six participants found to be heterozygous for the 185delAG mutation received results and were offered genetic counseling. Participants had consented for additional testing without receiving results and were screened for the 6174delT mutation in BRCA2, and seven were found to be positive. All identified carriers reported at least one first- or second-degree relative with a history of breast or ovarian cancer, although they did not all meet our study criteria for positive family history. Given these outcomes, we conclude that screening for breast and ovarian cancer susceptibility is most appropriate for individuals with a positive personal or positive family cancer history. We propose a guideline for future studies designed to identify individuals who may benefit from genetic testing for inherited breast and ovarian cancer. Images Figure 1 PMID:9150156

  17. X-ray detection of Nova Del 2013 with Swift

    NASA Astrophysics Data System (ADS)

    Castro-Tirado, Alberto J.; Martin-Carrillo, Antonio; Hanlon, Lorraine

    2013-08-01

    Continuous X-ray monitoring by Swift of Nova Del 2013 (see CBET #3628) shows an increase of X-ray emission at the source location compared to previous observations (ATEL #5283, ATEL #5305) during a 3.9 ksec observation at UT 2013-08-22 12:05. With the XRT instrument operating in window timing mode, 744 counts were extracted from a 50 pixel long source region and 324 counts from a similar box for a background region, resulting in a 13-sigma detection with a net count rate of 0.11±0.008 counts/sec.

  18. Visual and Near-IR Photometry of Nova Del 2013

    NASA Astrophysics Data System (ADS)

    Gehrz, R. D.; Dykhoff, D. A.; Shenoy, D. P.

    2013-08-01

    We report Visual and Near-IR photometry of Nova Del 2013 taken at the University of Minnesota's O'Brien Observatory (Marine-on-St-Croix, Minnesota, USA). VRIJHKLM photometry were obtained on two successive nights using an AsSi bolometer. Vega (alpha Lyrae) was used as the standard star. Our photometry show: August 16.2 UT: V = 4.8 +/- 0.1, R = 5.4 +/- 0.1, I = 5.2 +/- 0.1, J = 4.4 +/- 0.1, H = 4.3 +/- 0.1, K = 4.3 +/- 0.1, L = 4.5 +/- 0.2.

  19. Optical photometry and spectroscopy of Nova Del 2013

    NASA Astrophysics Data System (ADS)

    Tomov, T.; Ilkiewicz, K.; Swierczynski, E.; Belcheva, M.; Dimitrov, D.

    2013-08-01

    We report optical BV photometry and spectroscopy of Nova Del 2013, carried out between August 14.88 UT and August 15.08 UT. Using a 60 cm Cassegrain telescope at the Nicolaus Copernicus University Observatory (Torun, Poland) we estimated the V brightness of the Nova to be 6.31+/-0.02 mag and 6.18+/-0.03 mag on Aug. 14.94 UT and Aug. 15.02 UT respectively. HD 194113 (F2, V=8.00 mag) was used as a comparison star.

  20. Late Quaternary vegetation and climate of southern Tierra del Fuego

    NASA Astrophysics Data System (ADS)

    Heusser, Calvin J.

    1989-05-01

    Vegetation and climate over approximately the past 13,000 yr are reconstructed from fossil pollen in a 9.4-m mire section at Caleta Róbalo on Beagle Channel, Isla Navarino (54°56'S, 67°38'W), southern Tierra del Fuego. Fifty surface samples reflecting modern pollen dispersal serve to interpret the record. Chronologically controlled by nine radiocarbon dates, fossil pollen assemblages are: Empetrum-Gramineae- Gunnera-Tubuliflorae (zone 3b, 13,000-11,850 yr B.P.), Gramineae- Empetrum-assorted minor taxa (zone 3a, 11,850-10,000 yr B.P.), Nothofagus-Gramineae-Tubuliflorae-Polypodiaceae (zone 2, 10,000-5000 yr B.P.), Nothofagus-Empetrum (zone 1b, 5000-3000 yr B.P.), and Empetrum-Nothofagus (zone 1a, 3000-0 yr B.P.). Assemblages show tundra under a cold, dry climate (zone 3), followed by open woodland (zone 2), as conditions became warmer and less dry, and later, with greater humidity and lower temperatures, by closed forest and the spread of mires (zone 1). Comparisons drawn with records from Antarctica, New Zealand, Tasmania, and the subantarctic islands demonstrate broadly uniform conditions in the circumpolar Southern Hemisphere. The influences of continental and maritime antarctic air masses were apparently considerable in Tierra del Fuego during cold late-glacial time, whereas Holocene climate was largely regulated by interplay between maritime polar and maritime tropical air.

  1. 60. C.J.T., photographer December 23, 1955 KLAMATH RIVER BRIDGE, DEL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    60. C.J.T., photographer December 23, 1955 KLAMATH RIVER BRIDGE, DEL NORTE COUNTY, SECTION A, HIGHWAY 1. DN-1-A #538, KLAMATH RIVER BR. FROM SO. END, 12/23/55, C.J.T. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  2. 63. G.F.H., photographer July 30, 1932 DEL NORTE COUNTY, SECTION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    63. G.F.H., photographer July 30, 1932 DEL NORTE COUNTY, SECTION A, HIGHWAY 1. 1-DN A #124, STA. 164=00 SHOWING DRAINAGE CONDITIONS, G.F.H., 7-30-32. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  3. 62. R.L.T., photographer November 1, 1934 DEL NORTE COUNTY, SECTION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    62. R.L.T., photographer November 1, 1934 DEL NORTE COUNTY, SECTION D, HIGHWAY 1. REDWOOD CLEARING ON EXISTING LINE, 1-DN-71-A #26, R.L.T. 11-1-34. Stamped office copy. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  4. 61. M.C., photographer June 22, 1951 KLAMATH, DEL NORTE COUNTY, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    61. M.C., photographer June 22, 1951 KLAMATH, DEL NORTE COUNTY, SECTION A, HIGHWAY 1. DN-1-A #452 NORTHERLY THROUGH KLAMATH FROM STA. 325+50, 6/22/51, M.C. Stamped office copy. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  5. Primer registro para Peru del genero Nielsonia Young, 1977 (Hemiptera: Cicadellidae: Cicadellinae: Cicadellini)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    En este articulo se reporta por primera vez para el Peru una especies del genero Nielsonia Young, 1977, de material procedente del Departamento de Tumbes. El genero ha sido reportada anteriormente de Ecuador, como unico registro para Sudamerica, y America Central. El unico especimen hembra encontra...

  6. [Recommendations to improve the scientific comunication process in the Revista Médica del IMSS].

    PubMed

    Álvarez, Ivón

    2016-01-01

    In order to improve the position of the Revista Médica del Instituto Mexicano del Seguro Social among the different journals, in this editorial we enumerate a series of recommendations to ameliorate the practices of the different actors who participate in the scientific communication process of this journal. PMID:26820191

  7. High carrier frequency of the 35delG deafness mutation in European populations. Genetic Analysis Consortium of GJB2 35delG.

    PubMed

    Gasparini, P; Rabionet, R; Barbujani, G; Melçhionda, S; Petersen, M; Brøndum-Nielsen, K; Metspalu, A; Oitmaa, E; Pisano, M; Fortina, P; Zelante, L; Estivill, X

    2000-01-01

    Congenital deafness accounts for about 1 in 1000 infants and approximately 80% of cases are inherited as an autosomal recessive trait. Recently, it has been demonstrated that connexin 26 (GJB2) gene is a major gene for congenital sensorineural deafness. A single mutation (named 35delG) was found in most recessive families and sporadic cases of congenital deafness, among Caucasoids, with relative frequencies ranging from 28% to 63%. We present here the analysis of the 35delG mutation in 3270 random controls from 17 European countries. We have detected a carrier frequency for 35delG of 1 in 35 in southern Europe and 1 in 79 in central and northern Europe. In addition, 35delG was detected in five out of 376 Jewish subjects of different origin, but was absent in other non-European populations. The study suggests either a single origin for 35delG somewhere in Europe or in the Middle East, and the possible presence of a carrier advantage together with a founder effect. The 35delG carrier frequency of 1 in 51 in the overall European population clearly indicates that this genetic alteration is a major mutation for autosomal recessive deafness in Caucasoids. This finding should facilitate diagnosis of congenital deafness and allow early treatment of the affected subjects. PMID:10713883

  8. Efecto del Programa de Entrenamiento “Manejo del Dolor” en la Documentación de Enfermería en el Expediente Electrónico

    PubMed Central

    Monsiváis, María Guadalupe Moreno; Guzmán, Ma. Guadalupe Interial; Flores, Paz Francisco Sauceda; Arreola, Leticia Vázquez

    2012-01-01

    Resumen En el presente trabajo se muestra la importancia de entrenar al personal de enfermería para mejorar la documentación en el expediente electrónico. Se eligió el manejo del dolor por ser un área prioritaria; una alta proporción de pacientes en período post operatorio cursa con dolor, por lo tanto, la documentación debe ser útil para la toma de decisiones clínicas. Se implementó un programa de entrenamiento denominado “Manejo del Dolor” dirigido al personal de enfermería. Se utilizó la tecnología de la información como herramienta para fortalecer el conocimiento con base en la revisión sistemática de la literatura; el personal de enfermería participante seleccionó la mejor evidencia; posteriormente se trabajó en la transferencia de este conocimiento a la práctica a través del diseño de un protocolo para el manejo del dolor. Se concluye que el conocimiento del manejo del dolor es fundamental para que enfermería documente con mayor precisión sus intervenciones. PMID:24199106

  9. Disruption of cytokeratin-8 interaction with F508del-CFTR corrects its functional defect

    PubMed Central

    Colas, Julien; Faure, Grazyna; Saussereau, Emilie; Trudel, Stéphanie; Rabeh, Wael M.; Bitam, Sara; Guerrera, Ida Chiara; Fritsch, Janine; Sermet-Gaudelus, Isabelle; Davezac, Noëlie; Brouillard, Franck; Lukacs, Gergely L.; Herrmann, Harald; Ollero, Mario; Edelman, Aleksander

    2012-01-01

    We have previously reported an increased expression of cytokeratins 8/18 (K8/K18) in cells expressing the F508del mutation of cystic fibrosis transmembrane conductance regulator (CFTR). This is associated with increased colocalization of CFTR and K18 in the vicinity of the endoplasmic reticulum, although this is reversed by treating cells with curcumin, resulting in the rescue of F508del-CFTR. In the present work, we hypothesized that (i) the K8/K18 network may interact physically with CFTR, and that (ii) this interaction may modify CFTR function. CFTR was immunoprecipitated from HeLa cells transfected with either wild-type (WT) CFTR or F508del-CFTR. Precipitates were subjected to 2D-gel electrophoresis and differential spots identified by mass spectrometry. K8 and K18 were found significantly increased in F508del-CFTR precipitates. Using surface plasmon resonance, we demonstrate that K8, but not K18, binds directly and preferentially to the F508del over the WT human NBD1 (nucleotide-binding domain-1). In vivo K8 interaction with F508del-CFTR was confirmed by proximity ligation assay in HeLa cells and in primary cultures of human respiratory epithelial cells. Ablation of K8 expression by siRNA in F508del-expressing HeLa cells led to the recovery of CFTR-dependent iodide efflux. Moreover, F508del-expressing mice topically treated with K8-siRNA showed restored nasal potential difference, equivalent to that of WT mice. These results show that disruption of F508del-CFTR and K8 interaction leads to the correction of the F508del-CFTR processing defect, suggesting a novel potential therapeutic target in CF. PMID:22038833

  10. Disruption of cytokeratin-8 interaction with F508del-CFTR corrects its functional defect.

    PubMed

    Colas, Julien; Faure, Grazyna; Saussereau, Emilie; Trudel, Stphanie; Rabeh, Wael M; Bitam, Sara; Guerrera, Ida Chiara; Fritsch, Janine; Sermet-Gaudelus, Isabelle; Davezac, Nolie; Brouillard, Franck; Lukacs, Gergely L; Herrmann, Harald; Ollero, Mario; Edelman, Aleksander

    2012-02-01

    We have previously reported an increased expression of cytokeratins 8/18 (K8/K18) in cells expressing the F508del mutation of cystic fibrosis transmembrane conductance regulator (CFTR). This is associated with increased colocalization of CFTR and K18 in the vicinity of the endoplasmic reticulum, although this is reversed by treating cells with curcumin, resulting in the rescue of F508del-CFTR. In the present work, we hypothesized that (i) the K8/K18 network may interact physically with CFTR, and that (ii) this interaction may modify CFTR function. CFTR was immunoprecipitated from HeLa cells transfected with either wild-type (WT) CFTR or F508del-CFTR. Precipitates were subjected to 2D-gel electrophoresis and differential spots identified by mass spectrometry. K8 and K18 were found significantly increased in F508del-CFTR precipitates. Using surface plasmon resonance, we demonstrate that K8, but not K18, binds directly and preferentially to the F508del over the WT human NBD1 (nucleotide-binding domain-1). In vivo K8 interaction with F508del-CFTR was confirmed by proximity ligation assay in HeLa cells and in primary cultures of human respiratory epithelial cells. Ablation of K8 expression by siRNA in F508del-expressing HeLa cells led to the recovery of CFTR-dependent iodide efflux. Moreover, F508del-expressing mice topically treated with K8-siRNA showed restored nasal potential difference, equivalent to that of WT mice. These results show that disruption of F508del-CFTR and K8 interaction leads to the correction of the F508del-CFTR processing defect, suggesting a novel potential therapeutic target in CF. PMID:22038833

  11. Assessing Glacier Hazards At Ghiacciaio Del Belvedere, Macugnaga, Italian Alps

    NASA Astrophysics Data System (ADS)

    Haeberli, W.; Chiarle, M.; Mortara, G.; Mazza, A.

    The uppermost section of the Valle Anzasca behind and above the community of Macugnaga in the Italian Alps is one of the most spectacular high-mountain land- scapes in Europe, with gigantic rock walls and numerous steep hanging glaciers. Its main glacier, Ghiacciaio del Belvedere at the foot of the huge Monte Rosa east face, is a heavily debris-covered glacier flowing on a thick sediment bed. Problems with floods, avalanches and debris flows from this ice body have been known for extended time periods. Most recently, however, the evolution of this highly dynamic environ- ment has become more dramatic. An outburst of Lago delle Locce, an ice-dammed lake at the confluenec of the tributary Ghiacciaio delle Locce with Ghiacciaio del Belvedere, caused heavy damage in 1979 and necessitated site investigation and con- struction work to be done for flood protection. The intermittent glacier growth ten- dency in the 1970es induced strong bulging of the glacier surface and, in places, caused the glacier tongue to override historical morains and to destroy newly-grown forest stands. A surge-type flow acceleration started in the lower parts of the Monte- Rosa east face during summer 2000, leading to strong crevassing and deformation of Ghiacciaio del Belvedere and extreme bulging of its orographic right margin. High water pressure and accelerated movement lasted into winter 2001/2002: the ice now started overriding the LIA moraine near Rifugio Zamboni of the CAI. In addition but rather independently, a most active detachment zone for rock falls and debris flows developed for several years now in the east face of Monte Rosa, somewhat more to the south of the accelerated glacier movement and at an altitude where relatively warm permafrost must be expected. Besides the scientific interest in these phenomena, the growing hazard potential to the local infrastructure must be considered seriously. Es- pecially potentials for the destabilization of large rock and ice masses in the east face of Monte Rosa, for interruption of the access trail to the Rifugio Zamboni by overrid- ing and/or collapse of the lateral moraine, for impacts by ice invading various instal- lations (cable car, restaurant, ski runs, trails) near the moraine hill of Belvedere, and for sudden outbursts of pressurized subglacial water or the newly formed supraglacial lake must be envisaged.

  12. Students' Behaviors and Views of Paraphrasing and Inappropriate Textual Borrowing in an EFL Academic Setting

    ERIC Educational Resources Information Center

    Liao, Ming-Tzu; Tseng, Chiung-Ying

    2010-01-01

    This study examines skillful EFL writers' and less skillful writers' EFL performance and perceptions of paraphrasing and inappropriate text borrowing, the extent to which their performance matches perceptions, and the factors behind their problematic text borrowing. Ninety-five postgraduates and undergraduates in Taiwan accomplished a paraphrasing…

  13. Writing Material in Chemical Physics Research: The Laboratory Notebook as Locus of Technical and Textual Integration

    ERIC Educational Resources Information Center

    Wickman, Chad

    2010-01-01

    This article, drawing on ethnographic study in a chemical physics research facility, explores how notebooks are used and produced in the conduct of laboratory science. Data include written field notes of laboratory activity; visual documentation of "in situ" writing processes; analysis of inscriptions, texts, and material artifacts produced in the…

  14. [Sick bodies textualized through images: what contemporary intensive care units can teach us].

    PubMed

    Vargas, Mara Ambrosina de Oliveira; Meyer, Dagmar Estermann

    2003-01-01

    This paper belongs to a dissertation in which, what we have call "nursing worker cyborgizing" in intensive therapy is discussed. In order to carry out this discussion we based our work on cultural theorizing, as well as on Donna Haraway understanding of cyborg. For the corpses analysis manuals and assistance protocols were used. The methodological approach used in this work is the cultural analysis, as it has been used in the Poststructuralist Cultural Studies, in order to describe and analyze the production of images of sick bodies and its decoding process through a complex monitoring system in which sick bodies, machines and nursing practitioners, connect in different ways and effects. We have concluded that it is useful and relevant to consider and discuss these instances of production and diffusion of meanings attributed to the body, life, and the Nursing care. PMID:14692283

  15. [Textual research on the numbers of acupuncture-moxibustion books in the Republican period].

    PubMed

    Gang, Wei-Juan

    2013-09-01

    Based on the materials in the General Catalogue of Ancient Books of Traditional Chinese Medicine, together with the sources from other relevant tool books, investigation is made on the total number of the acu-moxibustion books appeared in the Republican period. It has been found that the medical works collected in the said General Catalogue is not in line with its own principles for collection. It is stressed that the exact time span for the collection is 1912-1949. A book appeared in a collections or serial book shouldn't be counted as a separate book, so as to avoid the double counting for the same book. Translated works and those by foreign authors should be excluded. As a result of the above rules, the total number of acu-moxibustion book of this period should be 201. PMID:24429042

  16. Mining for Meaning: The Use of Unstructured Textual Data in Information Systems Research

    ERIC Educational Resources Information Center

    Triplett, Janea Lynne

    2012-01-01

    The objectives of this research are to demonstrate how text was used in (1) developing a theory to examine collaborative interaction in virtual worlds, (2) creating a framework for improving the efficiency and effectiveness of dealing with large text datasets for social network analysis, and (3) approaching an understanding of the role of meaning…

  17. Is the Frame Broken? Seeking New Metaphors for Textual Study in English

    ERIC Educational Resources Information Center

    McKnight, Lucinda

    2015-01-01

    This article draws from a doctoral study of how female teachers design English curriculum around girls' popular culture in a contemporary coeducational secondary setting and focuses on how English teachers contemplate the study of texts in the space of school-based curriculum planning. The article presents an argument for reflexivity around how we…

  18. The Effect of Explicit Instruction of Textual Discourse Markers on Saudi EFL Learners' Reading Comprehension

    ERIC Educational Resources Information Center

    Al-Qahtani, Abdulaziz Ali

    2015-01-01

    Discourse markers (DMs) instruction is currently receiving an increasing amount of attention in the literature on second language learning. As noted by Al-Yaari, Al Hammadi, Alyami, and Almaflehi (2013), and Algouzi (2014), the use of DMs is insufficient to support the development of the language skills, especially reading, of Saudi English as a…

  19. Reading Repression: Textualizing the Linguistic Marginalization of Nonnative English-Speaking Teachers in Arizona

    ERIC Educational Resources Information Center

    Blum, Avram; Johnson, Eric J.

    2012-01-01

    This discussion draws attention to the discriminatory efforts of policymakers in Arizona to professionally marginalize public school teachers deemed to have an accent. In addition to debunking the linguistic and pedagogic validity of this policy, we emphasize the role of the media in the (re)construction and justification of language ideologies…

  20. "And They Got Married by the Church ...": "Crazy Stories" and the Possibilities of Collaborative Textual Transformations

    ERIC Educational Resources Information Center

    Simon, Lisa

    2009-01-01

    This article is informed by multiliteracies pedagogy which recognizes the dynamic nature of reading and writing, particularly in relation to the multiple languages, literacy practices, texts, modalities, and interactions that are part of our world. This framework offers educators a greater appreciation of students' collaborations and text…

  1. Textual Practitioners: A Comparison of Hypertext Theory and Phenomenology of Reading

    ERIC Educational Resources Information Center

    Carusi, Annamaria

    2006-01-01

    The article is an exploration of online reading from the perspective of theories of reading and interpretation based on literary theory and the phenomenology of reading literary text. One of its aims is to show that such theories can make a contribution to our understanding of reading and to our design of online reading spaces. The precursor of…

  2. (Im)plausibilities: A Rhizo-Textual Analysis of Policy Texts and Teachers' Work

    ERIC Educational Resources Information Center

    Honan, Eileen

    2004-01-01

    In this paper the author argues for the use of Deleuzian theories in educational contexts. In particular, she is interested in the use of the concept of rhizomes, and the analysis of texts as rhizomes, drawing on Deleuze and Guattari's work in "A Thousand Plateaus" (1987). She discusses the possibilities for using rhizomatics in educational…

  3. [Textual research of existing block-printed edition of Source of Acupuncture and Moxibustion (Zhenjiu Fengyuan)].

    PubMed

    Soldan, Jan; Ren, Yu-Lan; Zou, Peng; Liang, Fan-Rong

    2013-08-01

    Based on comprehensive arrangement and analysis of edition origin and development, system, characteristic, archive holding situation of Zhenjiu Fengyuan (Source of Acupuncture and Moxibustion writlen) by LI Xue-chuan in Qing dynasty, the error and mistakes in Summary of TCM Ancient books in China, Union Catalog of TCM Books and Grand Chinese Dictionary of Medical Books are pointed out. On the other hand, under full evaluation and comparison among three types of block-printed editions, Dihua Caotang edition in 2 years of Daoguang emperor, Qing Dynasty (about 1822) that is collected in the library of Beijing University of CM is considered as good edition. PMID:24195227

  4. Extraction of chemical-induced diseases using prior knowledge and textual information

    PubMed Central

    Pons, Ewoud; Becker, Benedikt F.H.; Akhondi, Saber A.; Afzal, Zubair; van Mulligen, Erik M.; Kors, Jan A.

    2016-01-01

    We describe our approach to the chemical–disease relation (CDR) task in the BioCreative V challenge. The CDR task consists of two subtasks: automatic disease-named entity recognition and normalization (DNER), and extraction of chemical-induced diseases (CIDs) from Medline abstracts. For the DNER subtask, we used our concept recognition tool Peregrine, in combination with several optimization steps. For the CID subtask, our system, which we named RELigator, was trained on a rich feature set, comprising features derived from a graph database containing prior knowledge about chemicals and diseases, and linguistic and statistical features derived from the abstracts in the CDR training corpus. We describe the systems that were developed and present evaluation results for both subtasks on the CDR test set. For DNER, our Peregrine system reached an F-score of 0.757. For CID, the system achieved an F-score of 0.526, which ranked second among 18 participating teams. Several post-challenge modifications of the systems resulted in substantially improved F-scores (0.828 for DNER and 0.602 for CID). RELigator is available as a web service at http://biosemantics.org/index.php/software/religator. PMID:27081155

  5. Is the Frame Broken? Seeking New Metaphors for Textual Study in English

    ERIC Educational Resources Information Center

    McKnight, Lucinda

    2015-01-01

    This article draws from a doctoral study of how female teachers design English curriculum around girls' popular culture in a contemporary coeducational secondary setting and focuses on how English teachers contemplate the study of texts in the space of school-based curriculum planning. The article presents an argument for reflexivity around how we

  6. Performance Style vs. Textual Substance: Elocutionism Reincarnated in the Contemporary Practice of Oral Interpretation.

    ERIC Educational Resources Information Center

    Kirch, Michael W.; Zeidler, Tom

    Oral interpreters have traditionally been taught to begin their work with an in-depth examination of the text. Thus, classes in oral interpretation have emphasized the importance of literary analysis. Before a student can attempt a performance, the text must be analyzed in detail, as fully as possible, in an attempt to understand the nuances…

  7. Reading and Seeing Themselves: Boys of Color and Textual (Non-)Connection

    ERIC Educational Resources Information Center

    Sciurba, Katie

    2011-01-01

    The discourse on multicultural literature has focused on providing children of color opportunities to "see themselves" in the texts they read. Since the 1920s, advocates like W.E.B. DuBois have stressed that "visibility" in literature fosters positive psychological development among underrepresented groups of children, in addition to promoting…

  8. Legitimizing Dialogue as Textual and Ideological Goal in Academic Writing for Assessment and Publication

    ERIC Educational Resources Information Center

    Lillis, Theresa

    2011-01-01

    The semiotic world that we inhabit (within and outside the academy) is fast changing in terms of the resources that are used and the practices in which many engage. Yet the institutional norms governing highly consequential academic texts--students' texts assessed as part of their disciplinary-based activity and scholars' papers submitted for…

  9. Textual Archaeology: Lessons in the History of Business Writing Pedagogy from a Medieval Oxford Scholar.

    ERIC Educational Resources Information Center

    Thomas, Martha Wetterhall

    2003-01-01

    Argues that Thomas Sampson, author of the 1396 "Modus Dictandi," deserves attention because of his work as a teacher. Explains that Sampson was a practitioner and instructor of the art of letter writing. Contends that Sampson's work is a discursive artifact yielding multiple insights into the origins of business communication as taught and…

  10. Texts as Mirrors, Texts as Windows: Black Adolescent Boys and the Complexities of Textual Relevance

    ERIC Educational Resources Information Center

    Sciurba, Katie

    2015-01-01

    Discussions of culturally relevant and "boy" literature stress the importance of offering readers occasions to see themselves in texts. However, young men of color have had few opportunities within this discourse to reveal their own experiences with literature. Rather than make presumptions about how texts serve as mirrors to them, as…

  11. Patterns of Enquiry: Textual Analysis of a Classroom Discussion Unit on Bee Feeding Behaviour.

    ERIC Educational Resources Information Center

    Binns, Richard W.

    This paper constitutes an analysis of "Honey Bee Communication: An Enquiry into Two Concepts of Animal Behavior," a unit of classroom discussion modules developed by the Patterns of Enquiry Project at the Ontario Institute for Studies in Education. The conceptual framework of the analysis consists of four major items: (1) descriptive…

  12. [Textual research on Huang shinüke (Huang's Obstetrics and Gynecology)].

    PubMed

    Wen, Jianfang; Wu, Tong

    2015-07-01

    Huang shi nü ke (Huang's Obstetrics and Gynecology), a handwritten copy of the Ming Dynasty passed on by Huang Xiaoyou, Yuanyi and Huang Dongjiu, and sorted out by Huang Yanrong, was a family medical book of Huang's obstetrics and gynecology in Xin'an, being a summary of their clinical experience.There were altogether 44 chapters divided into 4 parts, including general introduction, general principle of treatment, discussions on prenatal conditions and qi acquired from the mother, and gynecological diseases in sequence, with the appendixes of pulse diagnostics for differentiating male and female, and the 10-month methods of protecting the fetus. PMID:26815029

  13. A Textual Research on the First Private University in Modern China

    ERIC Educational Resources Information Center

    Tian, Zhengping; Chen, Taolan

    2008-01-01

    Recently there have been many viewpoints as to which private university was founded firstly in modern China. The schools, such as Fudan University (or the former Aurora Academy), Nankai University, China College, Wuchang Zhonghua University, Nanyang College and Zhengmeng Academy are all considered to be the first private university. From two…

  14. Language Legislation in the Belgian Colonial Charter of 1908: A Textual-Historical Analysis

    ERIC Educational Resources Information Center

    Meeuwis, Michael

    2015-01-01

    When in 1908 the Belgian government took over the Congo from King Leopold II, a charter was drafted that would serve as a constitution-like statutory code for the new colony. Article 3 in this "Colonial Charter" dealt with language and linguistic rights. It epitomized the duality of language questions with which Belgium remained faced

  15. Integrating Textual Thinking into the Introductory College-Level Foreign Language Classroom

    ERIC Educational Resources Information Center

    Maxim, Hiram H.

    2006-01-01

    One of the characteristics of the well-documented bifurcation in collegiate foreign language (FL) instruction is the difficult transition from lower- to upper-level instruction. Particularly pronounced are the expectations placed on readers at the upper level. No longer engaged in surface readings and sentence-level exercises that stay focused on…

  16. The Efficacy of Corrective Feedback and Textual Enhancement in Promoting the Acquisition of Grammatical Redundancies

    ERIC Educational Resources Information Center

    Lyddon, Paul A.

    2011-01-01

    Many second language acquisition researchers (e.g., Doughty & Williams, 1998; R. Ellis, 2007; Long, 1996, 2007; Lyster, Lightbown, & Spada, 1999; Russell & Spada, 2006) have advocated the use of negative feedback to promote learner noticing of errors and the internalization of correct forms. At the same time, the true efficacy of this practice is…

  17. Studies and Design Specifications for Computerized Measurement of Textual Comprehensibility. Final Report.

    ERIC Educational Resources Information Center

    Siegel, Arthur I.; And Others

    A previous report defined a series of 14 novel measures for determining the comprehensibility of English text on the basis of current psycholinguistic and Structure-of-Intellect concepts. That report not only suggested the potential usefulness of the measures but also conjectured about the feasibility of automating the calculation of these…

  18. Classification of images on the Internet by visual and textual information

    NASA Astrophysics Data System (ADS)

    Gevers, Theo; Aldershoff, Raango; Smeulders, Arnold W. M.

    1999-12-01

    In this paper, we study computational models and techniques to combine textural and image features for classification of images on Internet. A framework is given to index images on the basis of textural, pictorial and composite information. The scheme makes use of weighted document terms and color invariant image features to obtain a high-dimensional similarity descriptor to be used as an index. Based on supervised learning, the k-nearest neighbor classifier is used to organize images into semantically meaningful groups of Internet images. Internet images are first classified into photographical and synthetical images. After classifying images into photographical and synthetical images, we further classify photographical images into portraits and non-portraits. Further, synthetical images are classified into button and non-button images.

  19. Undocumented in a Documentary Society: Textual Borders and Transnational Religious Literacies

    ERIC Educational Resources Information Center

    Vieira, Kate

    2011-01-01

    While transnationalism has emerged as a growing area of interest in Writing Studies, the field has not fully examined how migrants' movement across national borders shapes their literacy practices. This article offers one answer to this question by reporting on an ethnographic study of the transnational religious literacies of a community of…

  20. [Textual research on Amara (Mangifera Indica Linn), Butea monsperma (Lam) Kuntze, and Ferula asatoitida L].

    PubMed

    Li, Zhaohua; Wang, Yulin

    2015-01-01

    In the Buddhist canons, there are lots of medicines imported from abroad recorded. The dictionary works of such Buddhist canons give detailed annotations and explanations to all these foreign medicines, from which we can investigate the features of all these medicines. It is also clear that these three medicines were imported into China no later than the Tang Dynasty. Amara was originally grown in the xi yu (Western Region) , now called Mango. Its form and connotation appeared no later than the eastern Han Dynasty, and the explanation of this medicine appears in the A Great Modern Dictionary of Chinese is wrong. While its explanation for Butea monsperma should be supplemented. There are two kinds of asafoitida, herbaceous and woody. Only the former one is used for medical purpose, and the annotation appeared in A Great Modern Dictionary of Chinese is problematic. PMID:26268251

  1. Problemes de L'Analyse Textuelle/Problems of Textual Analysis.

    ERIC Educational Resources Information Center

    Leon, Pierre R., Ed.; And Others

    This text compiles papers treating problems in literary analysis which were read at a conference at the University of Toronto, Canada. Papers include: (1) "Elements Phonostylistiques du Texte Litteraire," (2) Some uses of the Grammar in Poetic Analysis, (3) "Morphosyntaxe et Stylistique," (4) "Le Lexique dans l'Oeuvre Litteraire," (5) "Analyse…

  2. Discovering Potential Precursors of Mammography Abnormalities based on Textual Features, Frequencies, and Sequences

    SciTech Connect

    Patton, Robert M; Potok, Thomas E

    2010-01-01

    Diagnosingbreastcancerfrommammographyreportsisheav- ily dependant on the time sequences of the patient visits. In the work described, we take a longitudinal view of the text of a patient s mam- mogram reports to explore the existence of certain phrase patterns that indicate future abnormalities may exist for the patient. Our approach uses various text analysis techniques combined with Haar wavelets for the discovery and analysis of such precursor phrase patterns. We believe the results show significant promise for the early detection of breast can- cer and other breast abnormalities.

  3. Analysis of Textual Features of a New Reading Comprehension Assessment: MOCCA

    ERIC Educational Resources Information Center

    Seipel, Ben; Biancarosa, Gina; Carlson, Sarah; Davison, Mark

    2015-01-01

    Previous research has established two types of struggling readers: those who struggle with lower-level reading skills and those who struggle with higher-level reading skills (Cain & Oakhill, 2006; Perfetti, 2007). The latter group is commonly termed "poor comprehenders": readers who exhibit poor comprehension compared to peers with…

  4. Processing Spoken Discourse: Effects of Position and Emphasis on Judgments of Textual Coherence.

    ERIC Educational Resources Information Center

    Newman, Jean E.

    1985-01-01

    Describes three experiments that explored the informational roles of emphasis and word order in active sentences. The results, when considered together, strongly implicate recentness, but not emphasis, as an important means of linking temporally contiguous sentences. (HTH)

  5. Testing Visual Information Retrieval Methodologies Case Study: Comparative Analysis of Textual, Icon, Graphical, and "Spring" Displays.

    ERIC Educational Resources Information Center

    Morse, Emile; Lewis, Michael; Olsen, Kai A.

    2002-01-01

    Discussion of visual information retrieval systems focuses on an approach for testing novel interfaces that uses bottom-up, stepwise testing to allow evaluation of a visualization itself, rather than restricting evaluation to the system instantiating it. Presents a case study of undergraduates that compares a new visualization technique to more

  6. Preparing for Opening Night: Temporal Boundary Objects in Textually-Mediated Professional Practice

    ERIC Educational Resources Information Center

    Davies, Elisabeth; McKenzie, Pamela J.

    2004-01-01

    The authors report on two projects in which the role of documents as temporal boundary objects mediating information practices across multiple timelines was explored. It has been suggested that studying workplace documents will uncover the information practices of professionals beyond traditional information needs and uses studies. Two workplaces…

  7. Mining for Meaning: The Use of Unstructured Textual Data in Information Systems Research

    ERIC Educational Resources Information Center

    Triplett, Janea Lynne

    2012-01-01

    The objectives of this research are to demonstrate how text was used in (1) developing a theory to examine collaborative interaction in virtual worlds, (2) creating a framework for improving the efficiency and effectiveness of dealing with large text datasets for social network analysis, and (3) approaching an understanding of the role of meaning

  8. Contourlet Textual Features: Improving the Diagnosis of Solitary Pulmonary Nodules in Two Dimensional CT Images

    PubMed Central

    Wang, Jingjing; Sun, Tao; Gao, Ni; Menon, Desmond Dev; Luo, Yanxia; Gao, Qi; Li, Xia; Wang, Wei; Zhu, Huiping; Lv, Pingxin; Liang, Zhigang; Tao, Lixin; Liu, Xiangtong; Guo, Xiuhua

    2014-01-01

    Objective To determine the value of contourlet textural features obtained from solitary pulmonary nodules in two dimensional CT images used in diagnoses of lung cancer. Materials and Methods A total of 6,299 CT images were acquired from 336 patients, with 1,454 benign pulmonary nodule images from 84 patients (50 male, 34 female) and 4,845 malignant from 252 patients (150 male, 102 female). Further to this, nineteen patient information categories, which included seven demographic parameters and twelve morphological features, were also collected. A contourlet was used to extract fourteen types of textural features. These were then used to establish three support vector machine models. One comprised a database constructed of nineteen collected patient information categories, another included contourlet textural features and the third one contained both sets of information. Ten-fold cross-validation was used to evaluate the diagnosis results for the three databases, with sensitivity, specificity, accuracy, the area under the curve (AUC), precision, Youden index, and F-measure were used as the assessment criteria. In addition, the synthetic minority over-sampling technique (SMOTE) was used to preprocess the unbalanced data. Results Using a database containing textural features and patient information, sensitivity, specificity, accuracy, AUC, precision, Youden index, and F-measure were: 0.95, 0.71, 0.89, 0.89, 0.92, 0.66, and 0.93 respectively. These results were higher than results derived using the database without textural features (0.82, 0.47, 0.74, 0.67, 0.84, 0.29, and 0.83 respectively) as well as the database comprising only textural features (0.81, 0.64, 0.67, 0.72, 0.88, 0.44, and 0.85 respectively). Using the SMOTE as a pre-processing procedure, new balanced database generated, including observations of 5,816 benign ROIs and 5,815 malignant ROIs, and accuracy was 0.93. Conclusion Our results indicate that the combined contourlet textural features of solitary pulmonary nodules in CT images with patient profile information could potentially improve the diagnosis of lung cancer. PMID:25250576

  9. Extraction of chemical-induced diseases using prior knowledge and textual information.

    PubMed

    Pons, Ewoud; Becker, Benedikt F H; Akhondi, Saber A; Afzal, Zubair; van Mulligen, Erik M; Kors, Jan A

    2016-01-01

    We describe our approach to the chemical-disease relation (CDR) task in the BioCreative V challenge. The CDR task consists of two subtasks: automatic disease-named entity recognition and normalization (DNER), and extraction of chemical-induced diseases (CIDs) from Medline abstracts. For the DNER subtask, we used our concept recognition tool Peregrine, in combination with several optimization steps. For the CID subtask, our system, which we named RELigator, was trained on a rich feature set, comprising features derived from a graph database containing prior knowledge about chemicals and diseases, and linguistic and statistical features derived from the abstracts in the CDR training corpus. We describe the systems that were developed and present evaluation results for both subtasks on the CDR test set. For DNER, our Peregrine system reached anF-score of 0.757. For CID, the system achieved anF-score of 0.526, which ranked second among 18 participating teams. Several post-challenge modifications of the systems resulted in substantially improvedF-scores (0.828 for DNER and 0.602 for CID). RELigator is available as a web service athttp://biosemantics.org/index.php/software/religator. PMID:27081155

  10. Detecting Events and Patterns in Large-Scale User Generated Textual Streams with Statistical Learning Methods

    NASA Astrophysics Data System (ADS)

    Lampos, Vasileios

    Silicon is one promising semiconductor material to realize spin-based devices and circuits, not only because of its entrenchment in present-day charge-based microelectronics industry, but also due to its exceptionally long electron spin lifetime. This intrinsic spin lifetime of conduction electrons in bulk silicon was estimated by Yafet's theory assuming that intravalley electron-acoustic phonon scattering is the dominant spin-flip mechanism at equilibrium, which agrees with experimental results from early electron spin resonance measurements and recent spin transport measurements using ballistic hot-electron injection and detection. This dissertation details experimental observations of substantial electron spin relaxation in silicon due to extrinsic effects which do not originate from intravalley electron-acoustic phonon scattering. Spin transport in high electric field demonstrates a field-induced spin relaxation by phonon emission process during which electrons are scattered between conduction band valleys that reside on different crystal axes. Charge and spin transport measurements below 25 K demonstrate the existence of anomalous spin relaxation which stems from electron spin exchange interaction with bulk neutral donor spin. Using a two-dimensional finite-difference modeling scheme, spin relaxation during lateral spin transport near Si/SiO2 electrostatic gate interface is confirmed to be a result of enhanced momentum scattering and exchange coupling related to interfacial defects. These findings of extrinsic spin relaxation mechanisms are important to the design of spin-based semiconductor devices where the condition of equilibrium and the symmetry of bulk silicon lattice are necessarily broken.

  11. Textual Encounters of Three Kinds: Engaging in Reading through Community Astronomy Night

    ERIC Educational Resources Information Center

    Johnson, Amy Suzanne; Rezak, Achariya Tanya; Hodges, Georgia; Lawrence, Molly; Tippins, Deborah; Bongkotphet, Thitiya

    2008-01-01

    This article describes a community science night as a professional development experience for teachers in a rural school in the southeastern United States. As participants circulated through eight astronomy activities, they engaged in reading images, reading writing, and reading their natural and physical world. Through such diverse textual…

  12. The Measurement of Perspective Change through Textual Movement Patterns. Cognitive Science Research No. 59.

    ERIC Educational Resources Information Center

    Bierschenk, Bernhard

    A new approach to the study of text building behavior is possible through the application of Scanator. This paper consists of a demonstration of some of its fundamental functions. These are suitable in a study of text building. The basic concepts, expressed through an analysis of a small part of an interview text, derive from a thermodynamic…

  13. The Textual Organisation of Research Article Introductions in Applied Linguistics: Variability within a Single Discipline

    ERIC Educational Resources Information Center

    Ozturk, Ismet

    2007-01-01

    This paper explores the degree of variability in the structure of research article introductions within a single discipline. It is an exploratory study based on the analysis of 20 research articles. The study investigates the differences between two subdisciplines of applied linguistics, namely second language acquisition and second language…

  14. A Multi-Perspective Genre Analysis of the Barrister's Opinion: Writing Context, Generic Structure, and Textualization

    ERIC Educational Resources Information Center

    Hafner, Christoph A.

    2010-01-01

    In teaching and researching English for Law, considerable effort has been put into the fine-grained description of legal genres and accounts of associated legal literacy practices. Much of this work has been carried out in the academic context, focusing especially on genres encountered by undergraduate law students. The range of genres which must…

  15. Developing the Textual Turn: Tracking the Grammar of Research Case Records

    ERIC Educational Resources Information Center

    Thomson, Pat

    2005-01-01

    During action research projects a great deal of written material is produced. Some of this is data generated about the project, some about the process of the research and some is reflective writing about the researcher(s). In this article I propose that a deliberate focus on the tracking of texts might be helpful in action research, particularly…

  16. Semantic Development in Textual Contexts during the School Years: Noun Scale Analyses

    ERIC Educational Resources Information Center

    Ravid, Dorit

    2006-01-01

    The paper examines the nominal lexicon in later language acquisition as a window on linguistic knowledge and usage across childhood and adolescence. The paper presents a psycholinguistically motivated and cognitively grounded analysis of the distribution of ten semantic noun categories (the Noun Scale) across development, modality, and genre.…

  17. Institutional Shaping of Cultural Memory: Digital Library as Environment for Textual Transmission

    ERIC Educational Resources Information Center

    Dalbello, Marija

    2004-01-01

    The emerging trends in digital(ized) collection development from 1997 are examined using a sample of projects accessible through Web-based registries of the Association of Research Libraries and the Digital Library Federation. The analysis focuses on thematic repertoire, narrative structuring, underlying historiographic principles, presentation,…

  18. "Hey, I Didn't Say That!": Teaching Textual Integrity through Misrepresented Quotes

    ERIC Educational Resources Information Center

    Ford, Jessica L.

    2015-01-01

    Despite specialized areas of expertise, communication instructors are unified, to a large extent, by a singular belief: the meaning people give words produces behavioral ramifications (Mead, 2009). Communication instructors revere language's ability to reflect both meaning and reality. Yet, they also are tasked with the responsibility of conveying…

  19. [Textual research and differentiation of Dou Han-qing's works catalogue].

    PubMed

    Li, Bao-jin; Li, Tao-hua; Liu, Qing-guo

    2008-04-01

    This paper aims at probing into evolving course of DOU Han-qing's works catalogue. On the basis of summarizing and referring to study achievements of our predecessors, through analysis of book lists and relative works and chapters, it is hold that the catalogue which were not attained by ZHULiang-neng possibly are the contents of acupuncture reinforcing and reducing methods; the books printed and published by ZHULiang-neng include the contents of both channels and acupoints; the book, Zhinan, which was attained by DOUGui-fang, includes the content catalogue of needling methods; Fu Zhenjiu Zashuo in Zhenjiu Sisu. Zhenjiu Zhinan also were extracted by DOU Gui-fang from Illustrated Manual of Acupoints of the Bronze Figure, and The Zhenjiu Biji Taiyi Zhi Tuxu and Dongzhi Yezhe Gongshuo should belong to The Fu Zhenjiu Zashuo. PMID:18481729

  20. Semantic and Pragmatic Failure in Translating Literary Texts: Translators' Inconsistency and/or Textual Resistance

    ERIC Educational Resources Information Center

    AlBzoor, Baseel Ali

    2011-01-01

    Liyerature;Drawing upon intrinsic linguistic and cultural premises, the present study is an attempt to explore semantic and pragmatic failure, evidently and frequently arising while translating literary texts. This researcher has adopted a functional approach that hinges upon basic semantic and pragmatic premises that best fit the framework of an…

  1. Understanding Textual Authorship in the Digital Environment: Lessons from Historical Perspectives

    ERIC Educational Resources Information Center

    Velagic, Zoran; Hasenay, Damir

    2013-01-01

    Introduction: The paper explains how the modern understanding of authorship developed and sets out the problems to be considered when discussing digital authorship. Method: The contextual analysis of contents of the key themes is employed; in the articulation of the conclusions, analytic and synthetic approaches are used. Results: At each turning…

  2. The textual characteristics of traditional and Open Access scientific journals are similar

    PubMed Central

    Verspoor, Karin; Cohen, K Bretonnel; Hunter, Lawrence

    2009-01-01

    Background Recent years have seen an increased amount of natural language processing (NLP) work on full text biomedical journal publications. Much of this work is done with Open Access journal articles. Such work assumes that Open Access articles are representative of biomedical publications in general and that methods developed for analysis of Open Access full text publications will generalize to the biomedical literature as a whole. If this assumption is wrong, the cost to the community will be large, including not just wasted resources, but also flawed science. This paper examines that assumption. Results We collected two sets of documents, one consisting only of Open Access publications and the other consisting only of traditional journal publications. We examined them for differences in surface linguistic structures that have obvious consequences for the ease or difficulty of natural language processing and for differences in semantic content as reflected in lexical items. Regarding surface linguistic structures, we examined the incidence of conjunctions, negation, passives, and pronominal anaphora, and found that the two collections did not differ. We also examined the distribution of sentence lengths and found that both collections were characterized by the same mode. Regarding lexical items, we found that the Kullback-Leibler divergence between the two collections was low, and was lower than the divergence between either collection and a reference corpus. Where small differences did exist, log likelihood analysis showed that they were primarily in the area of formatting and in specific named entities. Conclusion We did not find structural or semantic differences between the Open Access and traditional journal collections. PMID:19527520

  3. Extraction of Temporal Networks from Term Co-Occurrences in Online Textual Sources

    PubMed Central

    Popović, Marko; Štefančić, Hrvoje; Sluban, Borut; Kralj Novak, Petra; Grčar, Miha; Mozetič, Igor; Puliga, Michelangelo; Zlatić, Vinko

    2014-01-01

    A stream of unstructured news can be a valuable source of hidden relations between different entities, such as financial institutions, countries, or persons. We present an approach to continuously collect online news, recognize relevant entities in them, and extract time-varying networks. The nodes of the network are the entities, and the links are their co-occurrences. We present a method to estimate the significance of co-occurrences, and a benchmark model against which their robustness is evaluated. The approach is applied to a large set of financial news, collected over a period of two years. The entities we consider are 50 countries which issue sovereign bonds, and which are insured by Credit Default Swaps (CDS) in turn. We compare the country co-occurrence networks to the CDS networks constructed from the correlations between the CDS. The results show relatively small, but significant overlap between the networks extracted from the news and those from the CDS correlations. PMID:25470498

  4. Critical Health Literacy: Shifting Textual-Social Practices in the Health Classroom

    ERIC Educational Resources Information Center

    Renwick, Kerry

    2014-01-01

    This paper will consider ways in which students are constructed as aliens in health classrooms. Creating the classroom as a setting for health promotion requires closer attention to those who make use of such space. If classrooms are places where diversity exists and is recognised, then health educators are challenged to consider how students are…

  5. A computer program for creating keyword indexes to textual data files

    USGS Publications Warehouse

    Moody, David W.

    1972-01-01

    A keyword-in-context (KWIC) or out-of-context (KWOC) index is a convenient means of organizing information. This keyword index program can be used to create either KWIC or KWOC indexes of bibliographic references or other types of information punched on. cards, typed on optical scanner sheets, or retrieved from various Department of Interior data bases using the Generalized Information Processing System (GIPSY). The index consists of a 'bibliographic' section and a keyword-section based on the permutation of. document titles, project titles, environmental impact statement titles, maps, etc. or lists of descriptors. The program can also create a back-of-the-book index to documents from a list of descriptors. By providing the user with a wide range of input and output options, the program provides the researcher, manager, or librarian with a means of-maintaining a list and index to documents in. a small library, reprint collection, or office file.

  6. Text-Based Recall and Extra-Textual Generations Resulting from Simplified and Authentic Texts

    ERIC Educational Resources Information Center

    Crossley, Scott A.; McNamara, Danielle S.

    2016-01-01

    This study uses a moving windows self-paced reading task to assess text comprehension of beginning and intermediate-level simplified texts and authentic texts by L2 learners engaged in a text-retelling task. Linear mixed effects (LME) models revealed statistically significant main effects for reading proficiency and text level on the number of…

  7. [Textual research on adulteration of Chinese materia medica in ancient China].

    PubMed

    Xie, Jin; Wang, De-Qun

    2013-09-01

    By investigating the mainstream works of herbal classics of successive ages, it is found that adulteration of Chinese materia medica appeared early in ancient China. The main methods of adulteration was producing fraud medicines in the Northern-Southern Dynasties, fake medicines began to appear in the Tang Dynasty, and status of adulteration of Chinese materia medica ran unchecked since the Ming and Qing Dynasty. By statistics, there were 76 kinds of adulteration varieties before the Republican period. The main varieties were precious drugs, animal drugs and artifacts. Commonly methods used in the process included forging and adulterating, dealing with 11 kinds and 68 kinds respectively. Adulteration probably lead to the result of imposing the changes of the used medicinal parts of Herba Pogostemonis; Radix Aconiti Lateralis prepared by adding salt, Radix Angelica Sinensis processed by wine, and Radix Astragalis seu Hedysaris processed with bee honey. However, the root cause of adulteration in Chinese materia medica was the dissociation of professional physician and pharmacist, resulting in the ignorance of medical practitioners became unable to recognize Chinese materia medica; and the immorality of medicinal merchants. Besides, rating the quality of materia medica based on its producing areas without differentiating the false from the genuine may also contribute to this result passively. PMID:24429032

  8. The Angle of Articulation in Textual Movement. Cognitive Science Research No. 60.

    ERIC Educational Resources Information Center

    Bierschenk, Bernhard

    Natural systems are self-organizing and stratify according to the angular articulation of their movements. In particular, movement is relative to the levels that define its behavior space. As natural phenomenon, text production is self-referential, In generating information, the intention of the producer of a text becomes specified. Specifying of

  9. Critical Health Literacy: Shifting Textual-Social Practices in the Health Classroom

    ERIC Educational Resources Information Center

    Renwick, Kerry

    2014-01-01

    This paper will consider ways in which students are constructed as aliens in health classrooms. Creating the classroom as a setting for health promotion requires closer attention to those who make use of such space. If classrooms are places where diversity exists and is recognised, then health educators are challenged to consider how students are

  10. Texts as Mirrors, Texts as Windows: Black Adolescent Boys and the Complexities of Textual Relevance

    ERIC Educational Resources Information Center

    Sciurba, Katie

    2015-01-01

    Discussions of culturally relevant and "boy" literature stress the importance of offering readers occasions to see themselves in texts. However, young men of color have had few opportunities within this discourse to reveal their own experiences with literature. Rather than make presumptions about how texts serve as mirrors to them, as

  11. Language Legislation in the Belgian Colonial Charter of 1908: A Textual-Historical Analysis

    ERIC Educational Resources Information Center

    Meeuwis, Michael

    2015-01-01

    When in 1908 the Belgian government took over the Congo from King Leopold II, a charter was drafted that would serve as a constitution-like statutory code for the new colony. Article 3 in this "Colonial Charter" dealt with language and linguistic rights. It epitomized the duality of language questions with which Belgium remained faced…

  12. BAAL/CUP Seminars 2013/Text Trajectories--Developing Dynamic Approaches to Textual Analysis

    ERIC Educational Resources Information Center

    Maybin, Janet; Lillis, Theresa

    2015-01-01

    This seminar took place on 19 April, 2013 at the Centre for Language and Communication, Faculty of Language and Education Studies, The Open University. The seminar was coordinated by Janet Maybin and Theresa Lillis and there were 28 participants, including four postgraduate students, from universities in Britain, Belgium and South Africa.

  13. Extra-Textual Talk in Shared Book Reading: A Focus on Questioning

    ERIC Educational Resources Information Center

    Anderson, Ann; Anderson, Jim; Lynch, Jacqueline; Shapiro, Jon; Kim, Ji Eun

    2012-01-01

    In this study we investigated the frequency and types of questions asked when parents read with their four-year-old children, the relationship between the frequency and types of questions parents and children asked, and the relationship between these and the children's early literacy knowledge. Forty dyads shared two narrative texts and two…

  14. Employing Textual and Facial Emotion Recognition to Design an Affective Tutoring System

    ERIC Educational Resources Information Center

    Lin, Hao-Chiang Koong; Wang, Cheng-Hung; Chao, Ching-Ju; Chien, Ming-Kuan

    2012-01-01

    Emotional expression in Artificial Intelligence has gained lots of attention in recent years, people applied its affective computing not only in enhancing and realizing the interaction between computers and human, it also makes computer more humane. In this study, emotional expressions were applied into intelligent tutoring system, where learners'…

  15. Matrix frequency analysis and its applications to language classification of textual data for English and Hebrew

    NASA Astrophysics Data System (ADS)

    Uchill, Joseph H.; Assadi, Amir H.

    2003-01-01

    The advent of the internet has opened a host of new and exciting questions in the science and mathematics of information organization and data mining. In particular, a highly ambitious promise of the internet is to bring the bulk of human knowledge to everyone with access to a computer network, providing a democratic medium for sharing and communicating knowledge regardless of the language of the communication. The development of sharing and communication of knowledge via transfer of digital files is the first crucial achievement in this direction. Nonetheless, available solutions to numerous ancillary problems remain far from satisfactory. Among such outstanding problems are the first few fundamental questions that have been responsible for the emergence and rapid growth of the new field of Knowledge Engineering, namely, classification of forms of data, their effective organization, and extraction of knowledge from massive distributed data sets, and the design of fast effective search engines. The precision of machine learning algorithms in classification and recognition of image data (e.g. those scanned from books and other printed documents) are still far from human performance and speed in similar tasks. Discriminating the many forms of ASCII data from each other is not as difficult in view of the emerging universal standards for file-format. Nonetheless, most of the past and relatively recent human knowledge is yet to be transformed and saved in such machine readable formats. In particular, an outstanding problem in knowledge engineering is the problem of organization and management--with precision comparable to human performance--of knowledge in the form of images of documents that broadly belong to either text, image or a blend of both. It was shown in that the effectiveness of OCR was intertwined with the success of language and font recognition.

  16. Textual Practitioners: A Comparison of Hypertext Theory and Phenomenology of Reading

    ERIC Educational Resources Information Center

    Carusi, Annamaria

    2006-01-01

    The article is an exploration of online reading from the perspective of theories of reading and interpretation based on literary theory and the phenomenology of reading literary text. One of its aims is to show that such theories can make a contribution to our understanding of reading and to our design of online reading spaces. The precursor of

  17. Ambitions and Responsibilities: A Textual Analysis of the Norwegian National Curriculum Regulations for Nursing Education

    ERIC Educational Resources Information Center

    Solbrekke, Tone Dyrdal; Heggen, Kristin; Engebretsen, Eivind

    2014-01-01

    Society assigns professional educational programs the responsibility to aid students in learning and dedicate expert knowledge to furthering the well-being of citizens. This demand calls for addressing the how educational policies prioritize learning professionals' responsibility. Inspired by the theory of Jacques Derrida, we deconstruct the…

  18. Power Relationships in Rumpelstiltskin: A Textual Comparison of a Traditional and a Reconstructed Fairy Tale

    ERIC Educational Resources Information Center

    Kelley, Jane E.

    2008-01-01

    Reconstructed fairy tales provide a different point of view and challenge the assumptions of a common set of values; for that reason, these stories provide a medium in which to examine power relationships in texts by applying a critical multicultural analysis (Botelho & Rudman, forthcoming, 2008, "A critical multicultural analysis of children's…

  19. Renewable energy load assessment for Boquillas Del Carmen Coahuila, Mexico

    SciTech Connect

    Foster, R.

    1995-08-01

    This report outlines the estimates that were made in 1992 of the potential load requirements for Boquillas del Carmen, a small Mexican village on the northern border of the state of Coahuila, Mexico near Big Bend National Park in southern Texas. The study was made to help determine the possibility that village might be electrified by solar or wind energy. Various estimates of are given of the potential load based on estimates ranging from basic use of lights, radio, television, and small household appliances to microwave ovens, refrigerators, and direct evaporative coolers. The low-energy consumption case was estimated to be at 23.0 kWh/month per residence per month, and the high-energy consumption case (with cooling) was 140.7 kWh/month per residence. On average, the typical residence is occupied by five individuals.

  20. Energy integrated farm system: Del Valle Hog Farm

    SciTech Connect

    Not Available

    1984-01-01

    The Del Valle Hog Farm, a Texas hog farm with grain crops, is designed to conserve energy through methane generation, alcohol production, and efficient use of electrical energy. The integrated energy concepts to be demonstrated are: methane generation from swine manure to produce electricity and heat for alcohol fermentation and distillation and to produce hot water for heating the digester reactors and the hog feeding pens; and alcohol production from milo and distillation of 170 proof alcohol by use of methane and generated electricity. Specific energy technologies to be implemented are: anaerobic digester; gas compressors to store methane for peak demands; engine generator powered by methane; waste-heat exchanger on engine generator to produce hot water; continuous-process alcohol facility to produce 24 gal/day; and crop management.

  1. Ozone studies in the Paso del Norte region

    NASA Astrophysics Data System (ADS)

    Becerra-Davila, Fernando

    The Paso del Norte region forms the largest contiguous bi-national conglomerate on the US-Mexico border. With a combined population of around 2 million inhabitants, the Paso del Norte region is isolated, more than 500 km away from the nearest urban area of comparable size, thus making it an ideal location for air quality studies of an isolated urban environment. The meteorological conditions leading to a high ozone episode in this region, such as the historical ozone episode of June 2006, are analyzed. It is well known that stagnation and minimal winds, high temperatures, and pressure ridges over the region are conducive to high ozone episodes. In addition, the planetary boundary height is studied to understand its impact on high ozone episodes. Several studies report that ground level ozone non-attainment regulations could be caused not only by local emissions, but also by atmospheric transport. In this work the atmospheric advection of pollutants into the region is analyzed using HYSPLIT backward trajectories. Furthermore, a novel backward trajectory clustering technique is implemented for the summer of 2006. The "ozone weekend effect" (OWE) is a phenomenon by which in some geographical regions ambient ozone concentrations tend to be higher on weekends than on weekdays, despite the lower emissions of ozone precursors during those days. The observed local OWE has never previously been studied in terms of the photolysis rates of four of the main ozone precursors. In this research a novel method that allows the calculation of actinic fluxes, photolysis frequencies and photolysis rates with a high degree of accuracy and reliability has been developed. This method utilizes a combination of the experimental data available for this region in conjunction with a radiative transfer model (TUV model). Three weekend-weekday cases during summers 2006, 2009 and 2010 are studied in this work. In this research, the photolysis impact on the local OWE is studied. The results obtained from this photolysis study demonstrate that the local ground level ozone formation is not only influenced by the strong solar radiation and changing aerosol makeup, but also by other heterogeneous factors and reactions. In addition, this research provided good evidence that the ground level ozone precursor regime in El Paso during the ozone episode of June 2006 was mostly VOC-limited. Much of this estimation was derived from measurements of local ambient VOC/NOx ratios. This finding shows that at least during June 2006, the non-linear surface ozone production increased during weekends compared to workdays in a habitually VOC-limited regime. The seasonal variations of columnar ozone as measured by a Multi-filter Rotating Shadowband instrument installed at the UTEP campus are analyzed for the first time for this region and results are presented. This investigation has addressed the problem of ground-level ozone formation in the Paso del Norte region. Urban ozone is a complex problem with many aspects that are not fully understood. In this investigation, a range of techniques has been used to address the study of local surface ozone episodes with the purpose of acquiring new insights and knowledge that will help understand and remediate the diverse atmospheric pollution events that affect this bi-national region recurrently. Innovative techniques were developed and used, ranging from the use of local ambient atmospheric pollution data to the utilization of complex modeling techniques to achieve the best possible computer results. Finally, the influence of ground level ozone concentrations in admissions to hospitals for this region due to respiratory diseases is analyzed. The comprehensive results obtained in this work will help to better understand ozone formation in the Paso del Norte Region for future policy regulation implementations.

  2. Near-IR Photometry of Nova Del 2013

    NASA Astrophysics Data System (ADS)

    Cass, C. A.; Carlon, L. R.; Corgan, T. D.; Dykhoff, A. D.; Gehrz, D. R.; Shenoy, P. D.

    2013-08-01

    Subjects: Infra-Red, Nova We report Near-IR photometry of Nova Del 2013 taken with the 0.76-m infrared telescope at the University of Minnesota's O'Brien Observatory (Marine on St. Croix, Minnesota, USA). RIJHKLM photometry were obtained on August 21.17 and 23.13 UT using an AsSi bolometer. Vega (alpha Lyrae) was used as the standard star. Our photometry show: August 21.17 UT: R = 5.1 +/- 0.1, I = 4.6 +/- 0.1, J = 4.6 +/- 0.1, H = 4.1 +/- 0.1, K = 3.9 +/- 0.1, L = 2.7 +/- 0.2, M = +2.2 +/- 0.2.

  3. [History of Instituto Nacional de Salud Ocupacional del Peru].

    PubMed

    Cossio-Brazzan, Juan M

    2012-06-01

    In Peru, the industry's development has made economic improvements but at the same time, it has had a major impact on the health of the workers; for that reason, it was necessary to generate control mechanisms. So, in 1940 it was created the Departmento de Higiene Industrial, which in 1956 was changed to Instituto de Salud Ocupacional, but it was deactivated in 1994. However, in 2001 it reappeared into the Ministerio de Salud organizational structure with the name of Instituto de Salud Ocupacional "Alberto Hurtado Abadía". Actually, it is the Centro Nacional de Salud Ocupacional y Protección del Ambiente para la Salud (CENSOPAS), organ of the Instituto Nacional de Salud which continues working in synergy with other institutions and sectors, making research to protect the health of exposed persons (workers and community) to contamination and risks associated with economic activities. PMID:22858781

  4. Circular structures of Bajada del Diablo (Argentina): geophysical signatures

    NASA Astrophysics Data System (ADS)

    Prezzi, C. B.; Orgeira, M. J.; Martinez, O.; Acevedo, R. D.; Ponce, F.; Goldmann, G.; Magneres, I.; Rabassa, J.

    2016-02-01

    Bajada del Diablo is located in the Northern Patagonian Massif, Chubut, Argentina. The study area includes several circular structures found in Miocene olivine basalts of the Quiñelaf Eruptive Complex and in the Late Pliocene/Early Pleistocene Pampa Sastre conglomerates. An impact origin has been proposed for these circular structures. With the aim of further investigate the proposed impact origin, topographic, gravimetric, magnetic, resistivity, paleomagnetic and electromagnetic surveys in two circular structures ("8" and "G") located in Pampa Sastre conglomerates and in basalts of the Quiñelaf Eruptive Complex were carried out. The new geophysical results support the hypothesis of an impact origin. However, the confirmation of such an origin through the findings of shock metamorphism evidences and/or the recovery of meteorites remains elusive.

  5. Phytoseiid mites (Acari: Phytoseiidae) from Patagonia and Tierra del Fuego.

    PubMed

    Ferragut, Francisco; Navia, Denise

    2015-01-01

    Predatory phytoseiid mites have been intensively studied and surveyed in the last decades because of their economic importance as biocontrol agents of agricultural pests. However, many regions of the world remain unexplored and the diversity of the family worldwide is still fragmentary. Up to date no phytoseiid species have been collected in the southernmost part of the Earth down to latitude 45º S. In this study Phytoseiidae were sampled from native vegetation in southern Argentina and Chile in the regions of Patagonia and Tierra del Fuego Island. Thirteen species were collected, five of which were previously described and eight, Chileseius australis n. sp., Neoseiulus mapuche n. sp., Typhlodromips valdivianus n. sp., T. fissuratus n. sp., Amblyseius grandiporus n. sp., A. caliginosus n. sp., Typhlodromus (Anthoseius) anomalos n. sp. and Metaseiulus parabrevicollis n. sp. are proposed as new to science and are described and diagnosed. PMID:26250248

  6. Circular structures of Bajada del Diablo (Argentina): geophysical signatures

    NASA Astrophysics Data System (ADS)

    Prezzi, C. B.; Orgeira, M. J.; Martinez, O.; Acevedo, R. D.; Ponce, F.; Goldmann, G.; Magneres, I.; Rabassa, J.

    2016-05-01

    Bajada del Diablo is located in the Northern Patagonian Massif, Chubut, Argentina. The study area includes several circular structures found in Miocene olivine basalts of the Quiñelaf Eruptive Complex and in the Late Pliocene/Early Pleistocene Pampa Sastre conglomerates. An impact origin has been proposed for these circular structures. With the aim of further investigate the proposed impact origin, topographic, gravimetric, magnetic, resistivity, palaeomagnetic and electromagnetic surveys in two circular structures (`8' and `G') located in Pampa Sastre conglomerates and in basalts of the Quiñelaf Eruptive Complex were carried out. The new geophysical results support the hypothesis of an impact origin. However, the confirmation of such an origin through the findings of shock metamorphism evidences and/or the recovery of meteorites remains elusive.

  7. Spatially Controlled Fe Isotope Variations at Torres del Paine

    NASA Astrophysics Data System (ADS)

    Gajos, N.; Lundstrom, C.

    2013-12-01

    Recent advances in mass-spectrometry have identified systematic trends of non-traditional stable isotope variation in igneous rocks with differentiation index. We present new Fe isotope data for the Torres del Paine igneous complex in southern Chile. The multi-composition pluton consists of a 1 km vertical exposure of homogenous granite overlying a contemporaneous and possibly cogenetic 0.5 km mafic gabbro suite. Whereas previous isotopic investigations do little to address variations across important magmatic contacts, this study focuses on a first-of-its-kind spatially dependent non-traditional stable isotope investigation of an igneous pluton. Samples were collected at Torres del Paine in spatially significant transects, focusing on major contacts between country rock, granite and mafic units. Results collected by bracketed double spike MC-ICP-MS (2s precision of ×0.03) show an increase in δ56Fe towards the high silica margins of the pluton with values as high as δ56Fe 0.36. Additionally, the data show a decrease in δ56Fe toward the mafic center of the pluton with δ56Fe values ranging from δ56Fe -0.05 to 0.18. Samples collected on the contact between the granite and mafic complex show intermediate values of δ56Fe= 0.18(×) 0.03. Country rock samples in contact with granite show an isotopically light signature of δ56Fe=0.04 (×) 0.03. Analysis of 50 samples in total show a trend of increasing δ56Fe with SiO2 content. The process responsible for Fe isotope variations remains debated but is suggested to reflect four mechanisms: (1) crustal assimilation, (2) fractional crystallization, (3) late stage fluid exsolution [1] and (4) thermal migration [3]. Preliminary results show that mechanisms #1 and #2 would produce isotopic signatures opposite of those seen at Torres del Paine and other plutonic rocks. Isotopically light Torres country rock samples reveal that assimilation of rocks would not produce the isotopically heavy granites seen at Torres. Based on experimental results [1] fractional crystallization involving magnetite-melt fractionation should produce isotopically light melts, contrary to the isotopic signature seen in Torres. On the other hand, magnetite-fluid experiments show that late-stage fluid exsolution in plutons has the potential to produce isotopic signatures similar to Torres del Paine [1]. However, the amount of fractionation is highly dependent on the amount of Fe saturated in the fluid. The fractionation trend of Fe is also consistent with thermal migration experiments [3]. The spatial partitioning of heavy Fe at the felsic margins of the pluton and light Fe at the mafic base of the pluton is also consistent with this mechanism. The co-variation with other non-traditional stable isotope systems provides a crucial test to assessing the effects of thermal migration. [1] Belinker et al. (2012) AGU Meeting Abstract. [2] Heimann A. et al. (2008) GCA 72, 4379-4396.[3] Lundstrom (2009) GCA 73, 5709-5729.

  8. The hydrothermal system of Nevado del Ruiz Volcano, Colombia

    SciTech Connect

    Lopez, D.A.L.

    1992-01-01

    Nevado del Ruiz is an andesitic stratovolcano located 150 km northwest of Bogota, Columbia characterized by a large hydrothermal system with two very distinctive types of water: acid sulfate waters, and bicarbonate and neutral chloride waters. The waters within each group fall in well-defined lines on compositional cross plots with an apparent lack of mixing between the two water types. The acid sulfate waters appear to be related to the north-west striking and seismically active Villamaria-Termales fault. The neutral chloride waters are clustered to the west and south-east of the volcano. The bicarbonate waters are more widespread. Several hydrothermally-altered samples from Nevado del Ruiz volcano hydrothermal system were analyzed using X-ray diffraction techniques. It was possible to distinguish two sets of mineral assemblages which correspond to the two water types. The acid sulfate waters produce cristobalite, sulfates, hematite or pyrite, sulfur and minor amounts of trydimite, kaolinite, smectite, and illite. The alteration products at the neutral chloride and bicarbonate waters include mainly carbonates and cristobalite. Simulation of the reaction between the hydrothermal fluids and the basaltic andesites of the lower volcanic units at Ruiz using the computer program CHILLER yielded mineral assemblages which are consistent with the observed alteration mineralogy. High chloride and sulfate concentrations, and helium and sulfur isotopes suggest that the acid sulfate waters have an important magmatic contribution. The composition of the neutral chloride an bicarbonate waters suggests mineral equilibria with feldspars and carbonates. Both types of waters appear to be the product of mixing of high salinity end members with different proportions of meteoric water. Linear variations in composition of the gases discharged at Ruiz suggested that the gas phase also represents mixing. Faults and contacts play a key role in the circulation of fluids at Ruiz.

  9. Isotope hydrology of groundwaters in the Pampa del Tamarugal, Chile

    NASA Astrophysics Data System (ADS)

    Fritz, P.; Suzuki, O.; Silva, C.; Salati, E.

    1981-09-01

    The water resources in northern Chile are extremely scarce and development is limited by this. This paper discusses the isotope hydrology of groundwaters in the Pampa del Tamarugal — an area of extreme aridity (rainfall < 1 mm/yr.) — whose groundwater resources are mined for the town of Iquique, as well as for industrial and agricultural purposes. The aim of the project was to obtain information on modern recharge and to delineate, if possible recharge environments. To obtain the necessary background information a precipitation survey in the high Andes, as well as spring- and surface-water studies were carried out. The results show that a well-defined meteoric water line exists where σ 2H = (7.8 σ 18O + 10.3)% , and altitude effects depend on air-mass movements and cannot be defined without a broader regional and detailed sampling programme. However, it is still possible to assign maximum altitudes of recharge to springs in the Andes and at the eastern border of the Pampa del Tamarugal. Comparison of these data with groundwater compositions show, that these groundwaters originate from infiltrating surface water rather than directly infiltrated precipitation. A dependence of individual groundwater systems on specific quebradas (river valleys) is recognized. However, low 14C activities indicate that most of the waters pumped today are fossil and at least several hundreds if not thousands of years old. Some minor subsurface recharge does occur at the foot of the Andes, especially at Pica where high-altitude waters discharge, but even there groundwater appears to be a diminishing resource.

  10. Max Brödel: his art, legacy, and contributions to neurosurgery through medical illustration.

    PubMed

    Patel, Smruti K; Couldwell, William T; Liu, James K

    2011-07-01

    Max Brödel is considered the father of modern medical illustration. This report reviews his contributions to neurosurgery as a medical illustrator. Max Brödel, a young artist from Leipzig, Germany, was hired at Johns Hopkins Hospital in 1894, where he illustrated an operative textbook of gynecology for Howard A. Kelly. Although Brödel did not have any formal medical training, he quickly acquired knowledge of anatomy, pathology, physiology, and surgery. Brödel's extraordinary illustrations were characterized by an aerial perspective that conveyed the surgeon's operative viewpoint and precise surgical anatomy. He masterfully incorporated tissue realism with cross-sectional anatomy to accentuate concepts while maintaining topographical accuracy. Brödel's reputation spread quickly and resulted in collaborations with prominent surgeons, such as Cushing, Halsted, and Dandy. Cushing, who also possessed artistic talent, became a pupil of Brödel and remained a very close friend. In 1911, Brödel was appointed the director of the Department of Art as Applied to Medicine at Johns Hopkins, the first academic department of its kind in the world. For the next several decades, he trained generations of renowned medical illustrators. Just as Osler, Halsted, and Cushing passed their skills and knowledge to future leaders of medicine and surgery, Brödel did the same for the field of medical illustration. The advancement of neurosurgical education has been greatly facilitated by Max Brödel's artistic contributions. His unique ability to synthesize art and medicine resulted in timeless illustrations that remain indispensable to surgeons. The art produced by his legacy of illustrators continues to flourish in neurosurgical literature today. PMID:21294618

  11. Spatial shell structure of the novas DQ Her and HR Del

    SciTech Connect

    Pilyogin, L.S.

    1986-03-01

    This paper considers the formation of the spatial shell structure of the novas DQ Her (1934) and HR Del (1967). It is shown that the existence of polar caps is due to the influence of the second component of the system on the angular distribution of the mass shell depth of the mainshell. The ratio of the mass shell depth in the equatorial ring and in the polar caps is 1.13 for DQ Her and 2.7 for HR Del. The ratio of the maximal densities in the equatorial ring and the polar caps is of order 3 for DQ Her and of order 70 for HR Del.

  12. Observaciones del CH interestelar y el continuo en 3,3 GHz

    NASA Astrophysics Data System (ADS)

    Olano, C. A.; Combi, J. A.; Pöppel, W.; Benaglia, P.; Sanz, A. J.; Bava, J. A.

    Se informa sobre el proyecto que se lleva a cabo en el IAR con el propósito de observar las líneas hiperfinas del estado fundamental del CH y el continuo en la banda de 3,3 GHz. El nuevo receptor construído en nuestro laboratorio para tal fin se instaló sobre uno de los radiotelescopios, funcionando conjuntamente con los sistemas de procesamiento actuales del IAR. Los resultados de las primeras observaciones, realizadas tanto en las líneas espectrales como en el continuo sobre fuentes conocidas, fueron satisfactorios.

  13. Resultados del relevamiento de HI en el Cielo Austral: 3. Relevamiento de Nubes de Alta Velocidad

    NASA Astrophysics Data System (ADS)

    Morras, R.; Bajaja, E.; Arnal, E. M.; Pöppel, W. G. L.

    Los resultados del relevamiento de HI del Hemisferio Austral fueron reprocesados con el fin de incrementar su sensibilidad. Así, se utilizó esta nueva base de datos con el fin de obtener un nuevo relevamiento de Nubes de Alta Velocidad en el cielo austral. El ruido r.m.s. alcanzado es de 0.015-0.020 K, con una resolución espectral de 8 km/seg. El cubrimiento espacial del relevamiento mejora en un factor 16 al realizado por Bajaja et al (1985).

  14. RASTREO DEL CANCER COLORRECTAL CONOCIMIENTO Y ACTITUD DE LA POBLACION

    PubMed Central

    CASAL, ENRIQUE R.; VELAZQUEZ, ELIZABETH N.; MEJIA, RAUL M.; CUNEO, ALDO; PEREZ-STABLE, ELISEO J.

    2014-01-01

    Resumen El rastreo de cáncer colorrectal (CCR) cuenta con fuertes evidencias en su favor. Datos preliminares indican que a pesar de ello no se lleva a cabo con la frecuencia adecuada. Se intenta aquí determinar, dentro de un Sistema de Salud que cuenta con los recursos necesarios, los elementos que facilitan o generan barreras para concretar esta práctica preventiva, cuántos individuos lo ponen en práctica y qué predice esta conducta. Se realizó una encuesta telefónica a los afiliados de una Obra Social de empleados de la Universidad de Buenos Aires, de los que 132 completaron el cuestionario (tasa de respuesta 70%). Los elementos considerados facilitadores del rastreo obtuvieron respuestas afirmativas en el 64 a 97%, mientras que los que definían barreras un 11 a 27%. En este último grupo, una categoría diferenciada la constituía el miedo a los efectos adversos: 39%, y el sentimiento de vergüenza relacionado con los procedimientos: 30%. Un 33% de los encuestados tenían hecho un método de rastreo, mayoritariamente de sangre oculta (27), sigmoideoscopía (11) y colonoscopía (20). Una mayoría afirmó que “se haría el procedimiento si el médico se lo recomendara” (95%), o “no se lo haría excepto que su médico se lo aconseje” (87%). Contestar afirmativamente que “los médicos hacen lo mejor para los pacientes” se asoció con haberse hecho un método de rastreo de CCR, OR 1.55 (IC 95%: 1.02-2.37) p: 0.04. El grupo de individuos estudiado parece bien predispuesto para el rastreo del CCR, la recomendación médica sería aquí un determinante prominente para ponerlo en práctica. PMID:19414294

  15. [Study on detection of samples of Rh-weak D and Del].

    PubMed

    Wang, Xiao-Zhu; Lan, Jiong-Cai; Wu, Xu-Hua; Zhou, Hua-You; Liu, Wei-Jia; Liu, Dan; Qi, Cun-Sheng; Zeng, Feng-Qin; Du, Ke-Qing

    2005-06-01

    To study the detection of weak D and Del from samples initially screened RhD(-), RhD phenotype was initially screened by routine serological test, out of which weak D phenotype was detected by indirect antiglobulin test (IAT) and Del phenotype was detected by chloroform-trichloroethylene absorption-elution test. The results showed that 56 samples were RhD(-) confirmed by routine serology test, which were screened out of 26 200 donors, among them 5 samples were typed as weak D by IAT and 9 cases samples were typed as Del by absorption-elution test. In conclusion, the samples which typed as RhD(-) by routine serological test must be identified by IAT and chloroform-trchloroethylene absorption test is order to detect weak D and Del phenotype. It is important for clinical transfusion safely. PMID:15972154

  16. Three cases of dup(10p)/del(10q) syndrome resulting from maternal pericentric inversion.

    PubMed

    Kulharya, A S; Schneider, N R; Wilson, G N

    1993-11-01

    Two families and 3 patients with dup(10p)/del(10q) syndrome segregating from a maternal pericentric inversion are described, including a stillborn female with Potter sequence and multicystic renal dysplasia. Comparison of 32 dup(10p) patients to 11 del(10)(q25) patients emphasized dolichocephaly, wide sutures, frontal bossing, micrognathia, and renal defects as distinguishing characteristics of the dup(10p) syndrome. The 3 new and 6 previously reported dup(10p)/del(10q) patients had several manifestations in common with the dup(10p) and del(10q) syndromes, but were more typical of dup(10p) syndrome with respect to all 5 distinguishing characters. PMID:8279477

  17. Seismicity following the 1985 eruption of Nevado del Ruiz, Colombia

    USGS Publications Warehouse

    Zollweg, J.E.

    1990-01-01

    Over 200 of the best-recorded earthquakes occurring near Nevado del Ruiz, Colombia, between December 1985 and May 1986 are examined for spatial patterns, information on local stress orientations, and evidence for seismogenic structures that may be related to magma-transport processes. These earthquakes occurred following the devastating eruption of November 13, 1985. Earthquake activity that is probably related to the volcanic system occurs over a large area, of the order of 50 km2. A pattern of earthquakes beneath the southern half of Ruiz may be the expression of a conduit system, but evidence is inconclusive due to low spatial resolution of most hypocenters. Epicenter and first-motion plots suggest most earthquakes occur on small faults of varying orientation. Most seismicity during this time period was unrelated to mapped faults, including some with Holocene offsets, except for the Villamaria Fault near Ruiz's northeast sector. Composite focal mechanisms show a variation of nearly 90?? in the strike of T-axes and indicate Ruiz is in a zone of local extension. ?? 1990.

  18. Status and perspectives of the INFN Laboratori Nazionali del Sud

    NASA Astrophysics Data System (ADS)

    Lattuada, M.

    2011-12-01

    The nuclear research carried out at the Laboratori Nazionali del Sud is mainly based on two ion accelerators, a 15 MV Tandem and a K800 superconductive cyclotron. The large variety of stable and radioactive beams produced and their wide energy range, together with the availability of high performance detection systems, allow for experimental research in the fields of the nuclear structure, reaction mechanisms and nuclear astrophysics. A continuous upgrading of the beam production and detection facilities is performed to mantain the role of the LNS in the panorama of the European nuclear laboratories. In addition the research activity in astroparticle physics led to the construction of two underwater laboratories in front of the Sicilian coast. They allow to check and validate submarine technologies in view of the realization of the European project KM3NeT, consisting in the installation of an observatory for high energy cosmic neutrinos in deep sea. All these experimental resources also represent formidable tools for applied researches that cover multidisciplinary fields concerning proton therapy, cultural heritage, seismology, environmental sciences and many others.

  19. ``Campo del Cielo'' Meteorites: Astronomical Heritage and Cultural Colonialism

    NASA Astrophysics Data System (ADS)

    López, Alejandro Martín; Altman, Agustina

    2012-09-01

    In the province of Chaco, Argentina, there is a very unique dispersion of metallic meteorites called ``Campo del Cielo''. One of the meteoric fragments of this dispersion, the meteorite called ``El Chaco'', consisting of 37 tons, is the second heaviest in the world. These meteorites are of great importance to the worldview of the Moqoit, aboriginal people that inhabit this region. For the local Creole population the meteorites are also relevant, that's why they have being cited in numerous documents and reports since the colonial period. During the first months of 2012, two Argentine artists and the Artistic Director of the German contemporary art exhibition called dOCUMENTA (13) tried to move ``El Chaco'' meteorite to Germany in order to exhibit it as an artistic object. Due to the fact that moving the meteorite could have a negative impact according to the Moqoit cosmology and that they were not able to participate in the decision they begun a manifestation against the movement of El Chaco. The opposition made by aboriginal communities and experts in cultural astronomy was able to stop the transfer. The whole process and its impact on the local community have promoted a deep discussion about art, science and cultural colonialism. In this paper we aim to address this debate and its consequences. This will allow us to think about contemporary forms of colonialism that are hidden in many scientific and artistic projects. Furthermore, we aim to debate about the most effective ways of protecting astronomical heritage in the Third World.

  20. MALARIA VECTORS IN SAN JOSÉDEL GUAVIARE, ORINOQUIA, COLOMBIA

    PubMed Central

    JIMÉNEZ, IRENE P.; CONN, JAN E.; BROCHERO, HELENA

    2015-01-01

    This study was conducted to determine Anopheles species composition and their natural infectivity by human Plasmodium in 2 localities with the highest malaria transmission in San Jose del Guaviare, Guaviare, Colombia. A total of 1,009 Anopheles mosquitoes were collected using human landing catches during 8 months in 2010. Anopheles darlingi was the most abundant (83.2%) followed by An. albitarsis s.l. (8.6%), Anopheles braziliensis (3.8%), An. oswaldoi s.l. (1%), and An. rangeli (0.3%). Anopheles darlingi showed the highest human biting rate, and it was found naturally infected with Plasmodium vivax VK210 (0.119%) using enzyme-linked immunosorbent assays. All species were collected biting both indoors and outdoors. Anopheles darlingi showed biting activity overnight with an indoor peak between 1200–0100 h. Therefore, we recommend that malaria prevention strategies focus on 1) insecticide-treated nets to reduce human–vector contact when people are most exposed and unprotected; 2) accurate diagnoses; 3) adequate treatment for patients; 4) more timely epidemiological notification; and 5) improved entomological surveillance. PMID:25102591

  1. Unravelling druggable signalling networks that control F508del-CFTR proteostasis.

    PubMed

    Hegde, Ramanath Narayana; Parashuraman, Seetharaman; Iorio, Francesco; Ciciriello, Fabiana; Capuani, Fabrizio; Carissimo, Annamaria; Carrella, Diego; Belcastro, Vincenzo; Subramanian, Advait; Bounti, Laura; Persico, Maria; Carlile, Graeme; Galietta, Luis; Thomas, David Y; Di Bernardo, Diego; Luini, Alberto

    2015-01-01

    Cystic fibrosis (CF) is caused by mutations in CF transmembrane conductance regulator (CFTR). The most frequent mutation (F508del-CFTR) results in altered proteostasis, that is, in the misfolding and intracellular degradation of the protein. The F508del-CFTR proteostasis machinery and its homeostatic regulation are well studied, while the question whether 'classical' signalling pathways and phosphorylation cascades might control proteostasis remains barely explored. Here, we have unravelled signalling cascades acting selectively on the F508del-CFTR folding-trafficking defects by analysing the mechanisms of action of F508del-CFTR proteostasis regulator drugs through an approach based on transcriptional profiling followed by deconvolution of their gene signatures. Targeting multiple components of these signalling pathways resulted in potent and specific correction of F508del-CFTR proteostasis and in synergy with pharmacochaperones. These results provide new insights into the physiology of cellular proteostasis and a rational basis for developing effective pharmacological correctors of the F508del-CFTR defect. PMID:26701908

  2. Targeting F508del-CFTR to develop rational new therapies for cystic fibrosis

    PubMed Central

    Cai, Zhi-wei; Liu, Jia; Li, Hong-yu; Sheppard, David N

    2011-01-01

    The mutation F508del is the commonest cause of the genetic disease cystic fibrosis (CF). CF disrupts the function of many organs in the body, most notably the lungs, by perturbing salt and water transport across epithelial surfaces. F508del causes harm in two principal ways. First, the mutation prevents delivery of the cystic fibrosis transmembrane conductance regulator (CFTR) to its correct cellular location, the apical (lumen-facing) membrane of epithelial cells. Second, F508del perturbs the Cl− channel function of CFTR by disrupting channel gating. Here, we discuss the development of rational new therapies for CF that target F508del-CFTR. We highlight how structural studies provide new insight into the role of F508 in the regulation of channel gating by cycles of ATP binding and hydrolysis. We emphasize the use of high-throughput screening to identify lead compounds for therapy development. These compounds include CFTR correctors that restore the expression of F508del-CFTR at the apical membrane of epithelial cells and CFTR potentiators that rescue the F508del-CFTR gating defect. Initial results from clinical trials of CFTR correctors and potentiators augur well for the development of small molecule therapies that target the root cause of CF: mutations in CFTR. PMID:21642944

  3. CHEK2 c.1100delC allele is rarely identified in Greek breast cancer cases.

    PubMed

    Apostolou, Paraskevi; Fostira, Florentia; Papamentzelopoulou, Myrto; Michelli, Maria; Panopoulos, Christos; Fountzilas, George; Konstantopoulou, Irene; Voutsinas, Gerassimos E; Yannoukakos, Drakoulis

    2015-04-01

    The CHEK2 gene encodes a protein kinase that plays a crucial role in maintenance of genomic integrity and the DNA repair mechanism. CHEK2 germline mutations are associated with increased risk of breast cancer and other malignancies. From a clinical perspective, the most significant mutation identified is the c.1100delC mutation, which is associated with an approximately 25% lifetime breast cancer risk. The distribution of this mutation shows wide geographical variation; it is more prevalent in the Northern European countries and less common, or even absent, in Southern Europe. In order to estimate the frequency of the CHEK2 c.1100delC mutation in Greek breast cancer patients, we genotyped 2,449 patients (2,408 females and 41 males), which was the largest series ever tested for c.1100delC. The mean age of female and male breast cancer diagnosis was 49 and 59 years, respectively. All patients had previously tested negative for the Greek BRCA1 founder and recurrent mutations. The CHEK2 c.1100delC mutation was detected in 0.16% (4 of 2,408) of females, all of whom were diagnosed with breast cancer before the age of 50 years. Only one c.1100delC carrier was reported with breast cancer family history. The present study indicates that the CHEK2 c.1100delC mutation does not contribute substantially to hereditary breast cancer in patients of Greek descent. PMID:25835597

  4. Unravelling druggable signalling networks that control F508del-CFTR proteostasis

    PubMed Central

    Hegde, Ramanath Narayana; Parashuraman, Seetharaman; Capuani, Fabrizio; Carissimo, Annamaria; Carrella, Diego; Belcastro, Vincenzo; Subramanian, Advait; Bounti, Laura; Persico, Maria; Carlile, Graeme; Galietta, Luis; Thomas, David Y; Di Bernardo, Diego; Luini, Alberto

    2015-01-01

    Cystic fibrosis (CF) is caused by mutations in CF transmembrane conductance regulator (CFTR). The most frequent mutation (F508del-CFTR) results in altered proteostasis, that is, in the misfolding and intracellular degradation of the protein. The F508del-CFTR proteostasis machinery and its homeostatic regulation are well studied, while the question whether ‘classical’ signalling pathways and phosphorylation cascades might control proteostasis remains barely explored. Here, we have unravelled signalling cascades acting selectively on the F508del-CFTR folding-trafficking defects by analysing the mechanisms of action of F508del-CFTR proteostasis regulator drugs through an approach based on transcriptional profiling followed by deconvolution of their gene signatures. Targeting multiple components of these signalling pathways resulted in potent and specific correction of F508del-CFTR proteostasis and in synergy with pharmacochaperones. These results provide new insights into the physiology of cellular proteostasis and a rational basis for developing effective pharmacological correctors of the F508del-CFTR defect. DOI: http://dx.doi.org/10.7554/eLife.10365.001 PMID:26701908

  5. El uso de la neuromodulación para el tratamiento del temblor

    PubMed Central

    Bendersky, Damián; Ajler, Pablo; Yampolsky, Claudio

    2014-01-01

    Introducción: El temblor puede ser un desorden incapacitante y el tratamiento de primera línea para estos pacientes es farmacológico. Sin embargo, este tratamiento puede llevar a una reducción satisfactoria del temblor en sólo el 50% de los pacientes con temblor esencial. La talamotomía era el tratamiento de elección para el temblor refractario al tratamiento médico hasta que comenzó a utilizarse la estimulación cerebral profunda (ECP) del núcleo ventral intermedio (Vim) del tálamo. En la actualidad, raramente se realiza la talamotomía. Métodos: Este artículo es una revisión no sistemática de las indicaciones, resultados, parámetros de programación y técnica quirúrgica de la ECP del Vim para el tratamiento del temblor. Resultados: Aunque los resultados clínicos son similares usando la talamotomía o la ECP del Vim, la primera causa más efectos adversos que la última. Además, la ECP puede ser usada bilateralmente, mientras que la talamotomía tiene un alto riesgo de causar disartria cuando se realiza de ambos lados. La ECP del Vim logró una adecuada mejoría del temblor en varias series de pacientes con temblor causado por temblor esencial, enfermedad de Parkinson o esclerosis múltiple. Además del Vim, hay otros blancos que están siendo usados por varios autores, tales como la zona incerta y las radiaciones prelemniscales. Conclusión: La ECP del Vim es un tratamiento útil para el temblor incapacitante refractario al tratamiento médico. Es esencial realizar una precisa selección de pacientes, así como utilizar una técnica quirúrgica correcta. Aún se desconoce el mejor blanco estereotáctico para el temblor, aunque el Vim es el más usado. PMID:25165613

  6. Bidimensional spectroscopy of HR Del shell with GMOS-IFU

    NASA Astrophysics Data System (ADS)

    Augusto, A.; Diaz, M.

    2006-06-01

    The slow and bright classical nova HR Del 1967 was observed in the optical using GEMINI-NORTH GMOS-IFU in 2002 with a spectral range from 0.4 μm to 1 μm, a resolution of ˜ 300 km/s, and spatial resolution of ˜ 0''.5. Line intensity maps were obtained for Hα +[NII], [OIII] 5007, Hβ and helium lines. The shell showed a bipolar and clumped structure resembling the shell observed in 1998 (Harman and O'Brien 2003). The [OIII] 5007 map showed seven bright knots. Models of the central source, shell and knots spectra were performed using CLOUDY 94 (Ferland et al. 1998) and RA3D (Diaz 2001). Central source spectra were best fitted with a T_{eff} = 60000 K, log(g) = 6 and log(L_*) = 36.6 Rauch atmosphere model. Shell H-density law was modeled using a power law with α parameter -1.2 and mass = 4.1 × 10^{-4} M_⊙. The knots spectra were fitted as gaussian condensations with ˜ 50000cm^{-3} peak H-density and ˜ 20000cm^{-3} average H-density. HeII 4686 emission was found in the knots. The HeII origin is atributted to projected emission from diffuse matter in front of the knots, hypothesis corroborated by about the same HeII intensity observed outside the knots. Physical parameters of the condensations were obtained from our analysis and helium abundances were recalculated. A peak density contrast N/N_S = 270 was found when compared to the medium outside the knots. Electron temperatures ˜ 9500 K, electron densities ˜ 20000cm^{-3} and helium number abundance ˜ 0.2 were derived. Our results showed a constant helium abundance within a narrow radius range which is consistent with impulsive ejection (Kato and Hachisu 1994).

  7. del-type universes in Palatini f(R) gravity

    NASA Astrophysics Data System (ADS)

    Santos, J.; Rebouças, M. J.; Oliveira, T. B. R. F.

    2010-06-01

    We examine the question as to whether the Palatini f(R) gravity theories permit space-times in which the causality is violated. We show that every perfect-fluid Gödel-type solution of Palatini f(R) gravity with density ρ and pressure p that satisfy the weak energy condition ρ+p≥0 is necessarily isometric to the Gödel geometry, demonstrating therefore that these theories present causal anomalies in the form of closed timelike curves. This result extends a theorem on Gödel-type models to the framework of Palatini f(R) gravity theory. We concretely examine the Gödel-type perfect-fluid solutions in specific f(R)=R-α/Rn Palatini gravity theory, where the free parameters α and n have been recently constrained by observational data. We show that for positive matter density and for α and n within the interval permitted by the observations, this theory does not admit the Gödel geometry as a perfect-fluid solution of its field equations. In this sense, this theory remedies the causal pathology in the form of closed timelike curves which is allowed in general relativity. We derive an expression for a critical radius rc (beyond which the causality is violated) for an arbitrary Palatini f(R) theory. The expression makes apparent that the violation of causality depends on the form of f(R) and on the matter content components. We also examine the violation of causality of Gödel-type by considering a single scalar field as the matter content. For this source we show that Palatini f(R) gravity gives rise to a unique Gödel-type solution with no violation of causality.

  8. Manipulating proteostasis to repair the F508del-CFTR defect in cystic fibrosis.

    PubMed

    Esposito, Speranza; Tosco, Antonella; Villella, Valeria R; Raia, Valeria; Kroemer, Guido; Maiuri, Luigi

    2016-12-01

    Cystic fibrosis (CF) is a lethal monogenic disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene that entails the (diagnostic) increase in sweat electrolyte concentrations, progressive lung disease with chronic inflammation and recurrent bacterial infections, pancreatic insufficiency, and male infertility. Therapies aimed at restoring the CFTR defect have emerged. Thus, a small molecule which facilitates chloride channel opening, the potentiator Ivacaftor, has been approved for the treatment of CF patients bearing a particular class of rare CFTR mutations. However, small molecules that directly target the most common misfolded CFTR mutant, F508del, and improve its intracellular trafficking in vitro, have been less effective than expected when tested in CF patients, even in combination with Ivacaftor. Thus, new strategies are required to circumvent the F508del-CFTR defect. Airway and intestinal epithelial cells from CF patients bearing the F508del-CFTR mutation exhibit an impressive derangement of cellular proteostasis, with oxidative stress, overactivation of the tissue transglutaminase (TG2), and disabled autophagy. Proteostasis regulators such as cysteamine can rescue and stabilize a functional F508del-CFTR protein through suppressing TG2 activation and restoring autophagy in vivo in F508del-CFTR homozygous mice, in vitro in CF patient-derived cell lines, ex vivo in freshly collected primary patient's nasal cells, as well as in a pilot clinical trial involving homozygous F508del-CFTR patients. Here, we discuss how the therapeutic normalization of defective proteostasis can be harnessed for the treatment of CF patients with the F508del-CFTR mutation. PMID:26976279

  9. Del(20q) in patients with chronic lymphocytic leukemia: A therapy-related abnormality involving lymphoid or myeloid cells

    PubMed Central

    Yin, C. Cameron; Tang, Guilin; Lu, Gary; Feng, Xiaoli; Keating, Michael J.; Medeiros, L. Jeffrey; Abruzzo, Lynne V.

    2015-01-01

    Del(20q), a common cytogenetic abnormality in myeloid neoplasms, is rare in chronic lymphocytic leukemia. We report 64 patients with chronic lymphocytic leukemia and del(20q), as the sole abnormality in 40, a stemline abnormality in 21, and a secondary abnormality in 3 cases. FISH analysis revealed an additional high-risk abnormality, del(11q) or del(17p), in 27/64 (42%) cases. In most cases, the leukemic cells showed atypical cytologic features, unmutated IGHV genes and ZAP70 positivity. The del(20q) was detected only after chemotherapy in all 27 cases with initial karyotypes available. With a median follow-up of 90 months, 30 patients (47%) died, most as a direct consequence of chronic lymphocytic leukemia. Eight patients developed a therapy-related myeloid neoplasm, seven with a complex karyotype. Combined morphologic and FISH analysis for del(20q) performed in 12 cases without morphologic evidence of a myeloid neoplasm localized the del(20q) to the chronic lymphocytic leukemia cells in 5 (42%) cases, and to myeloid/erythroid cells in 7 (58)% cases. The del(20q) was detected in myeloid cells in all 4 cases of myelodysplastic syndrome. In aggregate, these data indicate that chronic lymphocytic leukemia with del(20q) acquired after therapy is heterogeneous. In cases with morphologic evidence of dysplasia, the del(20q) likely resides in the myeloid lineage. However, in cases without morphologic evidence of dysplasia, the del(20q) may represent clonal evolution and disease progression. Combining morphologic analysis with FISH for del(20q) or performing FISH on immunomagnetically-selected subpopulations to localize the cell population with this abnormality may help guide patient management. PMID:25953391

  10. Modelo semi-empírico de protuberancia solar a partir del diagnóstico de densidades

    NASA Astrophysics Data System (ADS)

    Cirigliano, D.; Vial, J. C.; Rovira, M.

    A partir de la observación del espectro del quintuplete de C III alrededor de 1175 Å, se ha realizado el diagnóstico de la densidad y presión electrónica, basado en el cálculo del cociente de las intensidades observadas. Una vez establecida la densidad electrónica, y con el cálculo de las velocidades Doppler, hemos investigado el flujo de masa en la protuberancia en función de la temperatura. Estableciendo como hipótesis la conservación del número de partículas que ingresan y salen del cuerpo de la protuberancia, se investiga la variación del área de un tubo de flujo semi-empírico en función de la temperatura. A partir de dicho diagnóstico, se examina el comportamiento del radio del tubo magnético en función de la temperatura, los que dan cuenta de la abertura de las líneas de campo magnético que confinan el plasma y de la divergencia del campo magnético en diferentes alturas de la atmósfera solar.

  11. High mountain soils and periglacial features at the Torres del Paine, National Park Torres del Paine, Chile.

    NASA Astrophysics Data System (ADS)

    Senra, Eduardo; Schaefer, Carlos; Simas, Felipe; Gjorup, Davi

    2015-04-01

    The Torres del Paine National Park (TPNP) is located on the southern limit of the Andean Southern Ice Field, part of the Magallanes and Antartica Chilena region, in the province of Ultima Esperanza. The TPNP has a very heterogeneous climate due to orographic influence and wet air masses from the Pacific. The geology is basically Cretaceous metasedimentary rocks and Miocene granitic plutons and batholiths. We studied the main soils and geoenvironments of Mt Ferrier mountain and its surroundings, based on soils , landforms and vegetation aspects. The geoenvironmental stratification was based on the combined variation and integration of pedo-litho-geomorphological features with the vegetation. WE used detailed geological maps, a DEM and slope maps and WorlView II satellite images. Fifteen soils profiles were sampled and classified according to Soil Taxonomy (2010) at all genovironments, ranging from 50 m a.s.l to the at high plateau just below the permanent snowline, under periglacial conditions (~1004m asl). Three soil temperature and moisture monitoring sites were set, allowing for 24 consecutive months (2011 to 2013). Seven geoenvironments were identified with distinct soil and landform characteristics, all with a similar geological substrate. The landform and vegetation have a strong connection with the landscape dynamic, controlling erosional and depositional processes, resulting from glacier advances and retreats in the Late Quaternary. Wind blown materials is widespread, in the form of loess material, accumulating in the higher parts of the landscape. On the other hand, accumulation of organic matter in the water-saturated depressions is common in all altitudes. Generally the soils are acidic and dystrophic, with little exceptions. The following geoenvironments were identified: Periglacial Tundra, Loess slopes, Talus and scarpmentd, Fluvio-glacial terraces, Fluvio-lacustrine plains, Moraines and Paleodunes. The regional pedology show the occurrence of five soil orders (Soil Taxonomy, 2010): Histosols, Mollisols, Inceptsols, Entisols and Andisols.

  12. Using Del-1 to Tip the Angiogenic Balance in Endothelial Cells in Modular Constructs

    PubMed Central

    Ciucurel, Ema C.; Vlahos, Alexander E.

    2014-01-01

    Modular tissue engineering is a method of building vascularized tissue-engineered constructs. Submillimeter-sized collagen pieces (modules) coated with a layer of endothelial cells (EC; vascular component), and with embedded functional cells, are self-assembled into a larger, three-dimensional tissue. In this study, we examined the use of developmental endothelial locus-1 (Del-1), an extracellular matrix protein with proangiogenic properties, as a means of tipping the angiogenic balance in human umbilical vein endothelial cells incorporated in modular tissue-engineered constructs. The motivation was to enhance the vascularization of these constructs upon transplantation in vivo, in this case, without the use of exogenous mesenchymal stromal cells. EC were transduced using a lentiviral construct to overexpress Del-1. The Del-1 EC formed more sprouts in a fibrin gel sprouting assay in vitro compared with eGFP (control) transduced EC, as expected. Del-1 EC had a distinct profile of gene expression (upregulation of matrix metalloproteinase-9 [MMP-9], urokinase-type plasminogen activator [uPA/PLAU], vascular endothelial growth factor [VEGF-A], and intercellular adhesion molecule-1 [ICAM-1]; downregulation of angiopoietin-2 [Ang2]), also supporting the notion of “tipping the angiogenic balance”. On the other hand, contrary to our expectations, when Del-1 EC-coated modules were implanted subcutaneously in a severe combined immunodeficient/beige animal model, the proangiogenic effect of Del-1 was less remarkable. There was only a small increase in the number of blood vessels formed in Del-1 implants compared with the eGFP implants, and only few blood vessels formed at the implant site in both cases. This was presumed due to limited EC survival after transplantation. We speculate that if we could improve EC survival in our study (for example, by adding other prosurvival factors or supporting cells), we would see a greater Del-1-induced angiogenic benefit in vivo as a consequence of increased Del-1 secretion by a higher number of surviving cells. PMID:24138448

  13. La implantacion del enfoque constructivista en el aula de ciencia: Estudio de caso multiple

    NASA Astrophysics Data System (ADS)

    Arroyo Betancourt, Luz I.

    Esta investigacion estudia la implantacion del enfoque constructivista en tres aulas de ciencia del contexto puertorriqueno. Se auscultaron las practicas educativas que utilizan maestras consideradas constructivistas y la correspondencia de sus practicas educativas con los elementos esenciales de la didactica que proponen los teoricos de los planteamientos constructivistas. Se ausculto, ademas, a que vision del enfoque constructivista responden las expresiones de las maestras acerca de su practica educativa y como compara con su quehacer, a la luz de los elementos esenciales de las visiones constructivistas piagetiana, social y radical. Se utilizo el diseno de estudio descriptivo de caso multiple. El estudio se baso en entrevistas a profundidad, revision de documentos y observacion no participativa a la sala de clases. El contexto fueron tres escuelas publicas de la Region Educativa de San Juan, una elemental, una intermedia y una superior. Los resultados confirmaron que la transicion hacia el enfoque constructivista es un proceso que toma tiempo, dedicacion y la participacion en adiestramientos y readiestramientos acerca del nuevo enfoque. Las maestras coinciden en la mayoria de las practicas educativas que utilizan para implantar el enfoque constructivista de ensenanza y difieren en algunas debido, probablemente, a que han tenido que adaptarlas a los correspondientes niveles de ensenanza: elemental, intermedio y superior. Dos de las maestras planifican por conceptos generadores, mientras que una de ellas planifica siguiendo la guia que recibe del Departamento de Educacion. Difieren ademas, en el enfasis que confieren al inquirir cientifico. Con relacion a la correspondencia entre la vision manifestada por las maestras a la luz de las visiones piagetiana, social y radical, aparentemente, las preguntas del protocolo de entrevistas no lograron evocar la informacion con suficiente profundidad, por lo que la investigadora tuvo que inferir las visiones de las participantes basado en lo que estas manifestaron en su practica didactica. Dos maestras coinciden en una vision constructivista social de la construccion del conocimiento, del aprendizaje y de los metodos didacticos. La otra manifesto una vision constructivista piagetiana en el aprendizaje, los metodos didacticos y en la construccion del conocimiento. Se espera que este trabajo, ademas de promover los estudios de caso sobre el enfoque constructivista de ensenanza en el contexto puertorriqueno, sirva para que los maestros, que estan transformando su enfoque educativo de uno tradicional a uno constructivista, tengan una vision mas clara de la implantacion de este enfoque. Se espera ademas que sirva para que el Departamento de Educacion y sus programas de adiestramiento y readiestramiento en servicio, asi como las universidades y sus programas de preparacion de maestros, tomen en cuenta los resultados y recomendaciones de este estudio al revisar sus programas.

  14. The RGD finger of Del-1 is a unique structural feature critical for integrin binding

    SciTech Connect

    Schürpf, Thomas; Chen, Qiang; Liu, Jin-huan; Wang, Rui; Springer, Timothy A.; Wang, Jia-huai

    2012-11-13

    Developmental endothelial cell locus-1 (Del-1) glycoprotein is secreted by endothelial cells and a subset of macrophages. Del-1 plays a regulatory role in vascular remodeling and functions in innate immunity through interaction with integrin {alpha}{sub V}{beta}{sub 3}. Del-1 contains 3 epidermal growth factor (EGF)-like repeats and 2 discoidin-like domains. An Arg-Gly-Asp (RGD) motif in the second EGF domain (EGF2) mediates adhesion by endothelial cells and phagocytes. We report the crystal structure of its 3 EGF domains. The RGD motif of EGF2 forms a type II' {beta} turn at the tip of a long protruding loop, dubbed the RGD finger. Whereas EGF2 and EGF3 constitute a rigid rod via an interdomain calcium ion binding site, the long linker between EGF1 and EGF2 lends considerable flexibility to EGF1. Two unique O-linked glycans and 1 N-linked glycan locate to the opposite side of EGF2 from the RGD motif. These structural features favor integrin binding of the RGD finger. Mutagenesis data confirm the importance of having the RGD motif at the tip of the RGD finger. A database search for EGF domain sequences shows that this RGD finger is likely an evolutionary insertion and unique to the EGF domain of Del-1 and its homologue milk fat globule-EGF 8. The RGD finger of Del-1 is a unique structural feature critical for integrin binding.

  15. The 1985 Nevado del Ruiz volcano catastrophe: anatomy and retrospection

    NASA Astrophysics Data System (ADS)

    Voight, Barry

    1990-07-01

    This paper seeks to analyze in an objective way the circumstances and events that contributed to the 1985 Nevado del Ruiz catastrophe, in order to provide useful guidelines for future emergencies. The paper is organized into two principal parts. In the first part, an Anatomy of the catastrophe is developed as a step-by-step chronicle of events and actions taken by individuals and organizations during the period November 1984 through November 1985. This chronicle provides the essential background for the crucial events of November 13. This year-long period is broken down further to emphasize essential chapters: the gradual awareness of the awakening of the volcano; a long period of institutional skepticism reflecting an absence of credibility; the closure of the credibility gap with the September 11 phreatic eruption, followed by an intensive effort to gird for the worst; and a detailed account of the day of reckoning. The second part of the paper, Retrospection, examines the numerous complicated factors that influenced the catastrophic outcome, and attempts to cull a few "lessons from Armero" in order to avoid similar occurrences in the future. In a nutshell, the government on the whole acted responsibly but was not willing to bear the economic or political costs of early evacuation or a false alarm. Science accurately foresaw the hazards but was insufficiently precise to render reliable warning of the crucial event at the last possible minute. Catastrophe was therefore a calculated risk, and this combination — the limitations of predication/detection, the refusal to bear a false alarm and the lack of will to act on the uncertain information available — provided its immediate and most obvious causes. But because the crucial event occurred just two days before the Armero emergency-management plan was to be critically examined and improved, the numerous circumstances which delayed progress of emergency management over the previous year also may be said to have contributed to the outcome. Thus the catastrophe was not caused by technological ineffectiveness or detectiveness, nor by an overwhelming eruption, or by an improbable run of bad luck, but rather by cumulative human error — by misjudgment, indecision and bureaucratic shortsightedness. Armero could have produces no victims, and therein dwells its immense tragedy.

  16. The 1985 Nevado del Ruiz volcano catastrophe: anatomy and retrospection

    NASA Astrophysics Data System (ADS)

    Voight, Barry

    1990-12-01

    This paper seeks to analyze in an objective way the circumstances and events that contributed to the 1985 Nevado del Ruiz catastrophe, in order to provide useful guidelines for future emergencies. The paper is organized into two principal parts. In the first part, an Anatomy of the catastrophe is developed as a step-by-step chronicle of events and actions taken by individuals and organizations during the period November 1984 through November 1985. This chronicle provides the essential background for the crucial events of November 13. This year-long period is broken down further to emphasize important chapters: the gradual awareness of the awakening of the volcano; a long period of institutional skepticism reflecting an absence of credibility; the closure of the credibility gap with the September 11 phreatic eruption, followed by an intensive effort to gird for the worst; and a detailed account of the day of reckoning. The second part of the paper, Retrospection, examines the numerous complicated factors that influenced the catastrophic outcome, and attempts to cull a few "lessons from Armero" in order to avoid similar occurrences in the future. In a nutshell, the government on the whole acted responsibly but was not willing to bear the economic or political costs of early evacuation or a false alarm. Science accurately foresaw the hazards but was insufficiently precise to render reliable warning of the crucial event at the last possible minute. Catastrophe was therefore a calculated risk, and this combination - the limitations of prediction/detection, the refusal to bear a false alarm and the lack of will to act on the uncertain information available - provided its immediate and most obvious causes. But because the crucial event occurred just two days before the Armero emergency management plan was to be critically examined and improved, the numerous circumstances which delayed progress of emergency management over the previous year also may be said to have contributed to the outcome. Thus the catastrophe was not caused by technological ineffectiveness or defectiveness, nor by an overwhelming eruption, or by an improbable run of bad luck, but rather by cumulative human error - by misjudgment, indecision and bureaucratic shortsightedness. Armero could have produced no victims, and therein dwells its immense tragedy.

  17. Prospective Evaluation of a Transfusion Policy of RhD-Positive Red Blood Cells into DEL Patients in China

    PubMed Central

    Xu, Wei; Zhu, Mei; Wang, Bao-Long; Su, Hong; Wang, Min

    2015-01-01

    Summary Background The D antigen is highly immunogenic, requiring only a small quantity of transfused red blood cells (RBCs) to cause alloimmunization in D– immunocompetent recipients. DEL was reported arousing alloimmunization to true Rh– patients. Molecular studies of the RHD gene have revealed that DEL individuals retain a grossly intact RHD gene or have a portion of RHD in their genomes. Avoiding immunization with clinically important antibodies is a primary objective in transfusion medicine. Methods In order to determine whether pregnant DEL women carrying an RhD+ fetus are at risk of anti-D alloimmunization, 808 Rh– pregnant women with a history of gestations or parturitions who regularly visited hospitals for their prenatal anti-D screening and postpartum care from January 2011 to December 2012 were investigated. Samples were analyzed for DEL by PCR with specific primers, PCR-sequence-specific primers (PCR-SSP), reverse transcription-PCR (RT-PCR), PCRrestriction fragment length polymorphism (PCR-RFLP), and by gene sequencing to characterize different alleles. Results Among the 808 Rh– pregnant women of our sample, 178 (22.0%) were typed as DEL; 168 DEL samples were confirmed to have the RHD (1,227 G>A) allele, 8 DEL samples were characterized by one base mutation of the RHD (3G >A) allele, and the remaining two DEL samples were determined to carry RHD-CE(4–9)-D or RHD-CE(2–5)-D. The observation of allo-anti-D in two prominent D epitope loss cases confirmed the partial nature of these DEL phenotypes. Conclusions In conclusion, evidence is provided that different DEL genotypes code either for partial or complete D antigen expression. It is suggested that the use of RhD+ RBCs in complete D antigen DEL patients does not induce adverse reaction. PMID:25960711

  18. Pseudomonas aeruginosa Reduces VX-809 Stimulated F508del-CFTR Chloride Secretion by Airway Epithelial Cells

    PubMed Central

    Stanton, Bruce A.; Coutermarsh, Bonita; Barnaby, Roxanna; Hogan, Deborah

    2015-01-01

    Background P. aeruginosa is an opportunistic pathogen that chronically infects the lungs of 85% of adult patients with Cystic Fibrosis (CF). Previously, we demonstrated that P. aeruginosa reduced wt-CFTR Cl secretion by airway epithelial cells. Recently, a new investigational drug VX-809 has been shown to increase F508del-CFTR Cl secretion in human bronchial epithelial (HBE) cells, and, in combination with VX-770, to increase FEV1 (forced expiratory volume in 1 second) by an average of 3-5% in CF patients homozygous for the F508del-CFTR mutation. We propose that P. aeruginosa infection of CF lungs reduces VX-809 + VX-770- stimulated F508del-CFTR Cl secretion, and thereby reduces the clinical efficacy of VX-809 + VX-770. Methods and Results F508del-CFBE cells and primary cultures of CF-HBE cells (F508del/F508del) were exposed to VX-809 alone or a combination of VX-809 + VX-770 for 48 hours and the effect of P. aeruginosa on F508del-CFTR Cl secretion was measured in Ussing chambers. The effect of VX-809 on F508del-CFTR abundance was measured by cell surface biotinylation and western blot analysis. PAO1, PA14, PAK and 6 clinical isolates of P. aeruginosa (3 mucoid and 3 non-mucoid) significantly reduced drug stimulated F508del-CFTR Cl secretion, and plasma membrane F508del-CFTR. Conclusion The observation that P. aeruginosa reduces VX-809 and VX-809 + VX-770 stimulated F508del CFTR Cl secretion may explain, in part, why VX-809 + VX-770 has modest efficacy in clinical trials. PMID:26018799

  19. L'eliosismologia: onde sismiche per studiare l'interno del Sole

    NASA Astrophysics Data System (ADS)

    Di Mauro, M. P.

    2014-12-01

    Negli ultimi cinquanta anni siamo stati testimoni di una straordinaria rivoluzione della conoscenza e comprensione della nostra stella grazie alla nascita dell'Eliosismologia, lo studio delle oscillazioni solari. Analogamente a ciò che accade nella Terra durante i terremoti, anche l'interno del Sole è pervaso continuamente da onde sismiche che provocano piccole oscillazioni, ovvero deformazioni della fotosfera. Le oscillazioni sono la manifestazione di diversi processi che avvengono all'interno della struttura del Sole e le frequenze sismiche dei modi osservati e misurati sulla superficie sono legate direttamente ai parametri fisici degli strati interni attraversati dalle onde sismiche. Lo studio delle oscillazioni rappresenta, quindi, l'unico metodo diretto per studiare la struttura e la dinamica interna del Sole. In questo articolo verranno illustrate le caratteristiche generali delle oscillazioni solari e verranno presentati i risultati importanti e i progressi notevoli raggiunti grazie all'Eliosismologia.

  20. Deep source model for Nevado del Ruiz Volcano, Colombia, constrained by interferometric synthetic aperture radar observations

    NASA Astrophysics Data System (ADS)

    Lundgren, Paul; Samsonov, Sergey V.; López Velez, Cristian Mauricio; Ordoñez, Milton

    2015-06-01

    Nevado del Ruiz is part of a large volcano complex in the northern Andes of Colombia. Interferometric synthetic aperture radar observations from the RADARSAT-2 satellite since 2011 show steady inflation of the volcano since 2012 at 3-4 cm/yr. The broad (>20 km) deformation pattern from both ascending and descending track data constrain source models for either point or spheroidal sources, both located at >14 km beneath the surface (mean elevation 4.2 km) and 10 km SW of Nevado del Ruiz, below nearby Santa Isabel Volcano. Stress change computations for both sources in the context of a compressive regional stress indicate that dikes propagating from the source should become trapped in sills, possibly leading to a more complex pathway to the surface and explaining the significant lateral separation of the source and Nevado del Ruiz Volcano.

  1. Integrated global background monitoring network. Preliminary results from Torres del Paine and Olympic National Parks

    SciTech Connect

    Wiersma, G.B.; Kohler, A.; Boelcke, C.; Baker, G.; Harmon, M.; Weber, C.; Gonzales, J.

    1985-10-01

    During 1984, a pilot project was initiated for monitoring pollution at Torres del Paine National Park in southern Chile and Olympic National Park in the United States. These are two of three initial sites that are to be established as part of an integrated global backgound monitoring network. Eventually, the plan is to establish a world-wide system of such sites. We collected and analyzed samples of the soil, water, air, and two species of plants (moss and lichen). We also collected and analyzed samples of the forest litter. We compared the samples of soil and vegetation against reference samples. We also compared samples of soil, vegetation, and of organic material from Torres del Paine against similar samples from Olympic and Sequoia-Kings Canyon National Parks in the United States. Although the data is preliminary, it is in agreement with out initial hypothesis that Torres del Paine and Olympic National Parks are not a polluted sites.

  2. del-type metrics in Einstein-Aether theory II: nonflat background in arbitrary dimensions

    NASA Astrophysics Data System (ADS)

    Gürses, Metin; Şentürk, Çetin

    2016-05-01

    It was previously proved that the Gödel-type metrics with flat three-dimensional background metric solve exactly the field equations of the Einstein-Aether theory in four dimensions. We generalize this result by showing that the stationary Gödel-type metrics with nonflat background in D dimensions solve exactly the field equations of the Einstein-Aether theory. The reduced field equations are the (D-1)-dimensional Euclidean Ricci-flat and the (D-1)-dimensional source-free Maxwell equations, and the parameters of the theory are left free except c1-c3=1. We give a method to produce exact solutions of the Einstein-Aether theory from the Gödel-type metrics in D dimensions. By using this method, we present explicit exact solutions to the theory by considering the particular cases: (D-1)-dimensional Euclidean flat, conformally flat, and Tangherlini backgrounds.

  3. La relatività debole. La fisica dello spazio e del tempo senza paradossi

    NASA Astrophysics Data System (ADS)

    Selleri, Franco

    2011-06-01

    Secondo Einstein e Poincaré la simultaneità di eventi che hanno luogo in punti diversi dello spazio può essere definita solo per convenzione. Dal punto di vista matematico si dimostra, quindi, che due diverse definizioni di simultaneità corrispondono a due diversi valori del coefficiente e1 della variabile spaziale x presente nelle trasformazioni di Lorentz. A partire da premesse normalmente accettate otterremo diverse dimostrazioni della necessità di reintrodurre il concetto di simultaneità assoluta. Le conseguenze cosmologiche della nuova struttura dello spazio e del tempo andranno contro la cosmologia del Big Bang. Inoltre, dopo questi risultati, il relativismo sopravviverà in una forma meno aspra ("relatività debole") perché risulter privo di quel campionario di paradossi portato dalla teoria della Relatività Speciale.

  4. CASE REPORT: Phenotypic presentation of the Ser63Del MPZ mutation

    PubMed Central

    Miller, Lindsey J.; Patzko, Agnes; Lewis, Richard A.; Shy, Michael E.

    2013-01-01

    Mutations in MPZ cause CMT1B, the second most frequent cause of CMT1. Elegant studies with Ser63del mice suggest that Ser63del MPZ is retained in the ER where it activates the unfolded protein response (UPR) that contributes to the neuropathy. Clinical information about patients with this mutation is limited. We present clinical and electrophysiological data on a large multigenerational family with CMT1B caused by Ser63del MPZ. The patients have a classical CMT1 phenotype that is much less severe than that of patients with Arg98Cys MPZ that also activates the UPR. These results suggest that clinical presentation along cannot predict which MPZ mutations will be retained in the ER and activate the UPR. PMID:22734905

  5. Mejoras en el apuntado del telescopio de 2,15 mts de CASLEO

    NASA Astrophysics Data System (ADS)

    Aballay, J. L.; Casagrande, A. R.; Pereyra, P. F.; Marún, A. H.

    Con el objeto de optimizar el funcionamiento del telescopio de 2,15 mts. de CASLEO, se están eliminando los motores de calar, de guía y mecánica asociada. Para ésto, se están diseñando dos electrónicas que gobernarán, solamente, el motor de slew y el de tracking. Con el control del motor de slew se realizarán las funciones de slew y calar, controlando desde una PC la placa que maneja las rampas de velocidad. De este modo, el movimiento será programado y por lo tanto, más suave y preciso. Con el control del motor de tracking, a través de un generador de frecuencias programable desde una PC, se proveerá los movimientos necesarios para el tracking y guía.

  6. Biotic association and palaeoenvironmental reconstruction of the "Loma del Pterodaustro" fossil site (Early Cretaceous, Argentina)

    USGS Publications Warehouse

    Chiappe, L.; Rivarola, D.; Cione, A.; Fregenal-Martinez, M.; Sozzi, H.; Buatois, L.; Gallego, O.; Laza, J.; Romero, E.; Lopez-Arbarello, A.; Buscalioni, A.; Marsicano, C.; Adamonis, S.; Ortega, F.; McGehee, S.; Di, Iorio O.

    1998-01-01

    A sedimentological analysis of the basal section of the Early Cretaceous, lacustrine Lagarcito Formation at "Loma del Pterodaustro" (San Luis, Argentina) and a summary of its biological components are presented. Three sedimentological facies can be recognized in the basal sequence of the Lagarcito Formation. Fossil remains are particularly abundant in laminated claystones of a facies interpreted as deposits formed in offshore areas of the lake. The preservation of delicate structures allows recognition of these deposits as a Konservat Lagersta??tte. Up to now, rocks at "Loma del Pterodaustro" have yielded plants, conchostracans, semionotid and pleuropholid fishes, pterodactyloid pterosaurs, and a variety of invertebrate traces. The chronology of the Lagarcito Formation is discussed and it is concluded that this unit is of Albian age. The palaeoenvironment of deposition of the basal sequence of the Lagarcito Formation at "Loma del Pterodaustro" is interpreted as a perennial, shallow lake developed within an alluvial plain, under semiarid climatic conditions.

  7. Development and Utilization of InDel Markers to Identify Peanut (Arachis hypogaea) Disease Resistance.

    PubMed

    Liu, Lifeng; Dang, Phat M; Chen, Charles Y

    2015-01-01

    Peanut diseases, such as leaf spot and spotted wilt caused by Tomato Spotted Wilt Virus, can significantly reduce yield and quality. Application of marker assisted plant breeding requires the development and validation of different types of DNA molecular markers. Nearly 10,000 SSR-based molecular markers have been identified by various research groups around the world, but less than 14.5% showed polymorphism in peanut and only 6.4% have been mapped. Low levels of polymorphism limit the application of marker assisted selection (MAS) in peanut breeding programs. Insertion/deletion (InDel) markers have been reported to be more polymorphic than SSRs in some crops. The goals of this study were to identify novel InDel markers and to evaluate the potential use in peanut breeding. Forty-eight InDel markers were developed from conserved sequences of functional genes and tested in a diverse panel of 118 accessions covering six botanical types of cultivated peanut, of which 104 were from the U.S. mini-core. Results showed that 16 InDel markers were polymorphic with polymorphic information content (PIC) among InDels ranged from 0.017 to 0.660. With respect to botanical types, PICs varied from 0.176 for fastigiata var., 0.181 for hypogaea var., 0.306 for vulgaris var., 0.534 for aequatoriana var., 0.556 for peruviana var., to 0.660 for hirsuta var., implying that aequatoriana var., peruviana var., and hirsuta var. have higher genetic diversity than the other types and provide a basis for gene functional studies. Single marker analysis was conducted to associate specific marker to disease resistant traits. Five InDels from functional genes were identified to be significantly correlated to tomato spotted wilt virus (TSWV) infection and leaf spot, and these novel markers will be utilized to identify disease resistant genotype in breeding populations. PMID:26617627

  8. Development and Utilization of InDel Markers to Identify Peanut (Arachis hypogaea) Disease Resistance

    PubMed Central

    Liu, Lifeng; Dang, Phat M.; Chen, Charles Y.

    2015-01-01

    Peanut diseases, such as leaf spot and spotted wilt caused by Tomato Spotted Wilt Virus, can significantly reduce yield and quality. Application of marker assisted plant breeding requires the development and validation of different types of DNA molecular markers. Nearly 10,000 SSR-based molecular markers have been identified by various research groups around the world, but less than 14.5% showed polymorphism in peanut and only 6.4% have been mapped. Low levels of polymorphism limit the application of marker assisted selection (MAS) in peanut breeding programs. Insertion/deletion (InDel) markers have been reported to be more polymorphic than SSRs in some crops. The goals of this study were to identify novel InDel markers and to evaluate the potential use in peanut breeding. Forty-eight InDel markers were developed from conserved sequences of functional genes and tested in a diverse panel of 118 accessions covering six botanical types of cultivated peanut, of which 104 were from the U.S. mini-core. Results showed that 16 InDel markers were polymorphic with polymorphic information content (PIC) among InDels ranged from 0.017 to 0.660. With respect to botanical types, PICs varied from 0.176 for fastigiata var., 0.181 for hypogaea var., 0.306 for vulgaris var., 0.534 for aequatoriana var., 0.556 for peruviana var., to 0.660 for hirsuta var., implying that aequatoriana var., peruviana var., and hirsuta var. have higher genetic diversity than the other types and provide a basis for gene functional studies. Single marker analysis was conducted to associate specific marker to disease resistant traits. Five InDels from functional genes were identified to be significantly correlated to tomato spotted wilt virus (TSWV) infection and leaf spot, and these novel markers will be utilized to identify disease resistant genotype in breeding populations. PMID:26617627

  9. An unexpected effect of TNF-α on F508del-CFTR maturation and function.

    PubMed

    Bitam, Sara; Pranke, Iwona; Hollenhorst, Monika; Servel, Nathalie; Moquereau, Christelle; Tondelier, Danielle; Hatton, Aurélie; Urbach, Valérie; Sermet-Gaudelus, Isabelle; Hinzpeter, Alexandre; Edelman, Aleksander

    2015-01-01

    Cystic fibrosis (CF) is a multifactorial disease caused by mutations in the cystic fibrosis transmembrane conductance regulator gene ( CFTR), which encodes a cAMP-dependent Cl (-) channel. The most frequent mutation, F508del, leads to the synthesis of a prematurely degraded, otherwise partially functional protein. CFTR is expressed in many epithelia, with major consequences in the airways of patients with CF, characterized by both fluid transport abnormalities and persistent inflammatory responses. The relationship between the acute phase of inflammation and the expression of wild type (WT) CFTR or F508del-CFTR is poorly understood. The aim of the present study was to investigate this effect. The results show that 10 min exposure to TNF-alpha (0.5-50ng/ml) of F508del-CFTR-transfected HeLa cells and human bronchial cells expressing F508del-CFTR in primary culture (HBE) leads to the maturation of F508del-CFTR and induces CFTR chloride currents. The enhanced CFTR expression and function upon TNFα is sustained, in HBE cells, for at least 24 h. The underlying mechanism of action involves a protein kinase C (PKC) signaling pathway, and occurs through insertion of vesicles containing F508del-CFTR to the plasma membrane, with TNFα behaving as a corrector molecule. In conclusion, a novel and unexpected action of TNFα has been discovered and points to the importance of systematic studies on the roles of inflammatory mediators in the maturation of abnormally folded proteins in general and in the context of CF in particular. PMID:26594334

  10. An unexpected effect of TNF-α on F508del-CFTR maturation and function

    PubMed Central

    Bitam, Sara; Urbach, Valérie; Sermet-Gaudelus, Isabelle; Hinzpeter, Alexandre; Edelman, Aleksander

    2015-01-01

    Cystic fibrosis (CF) is a multifactorial disease caused by mutations in the cystic fibrosis transmembrane conductance regulator gene ( CFTR), which encodes a cAMP-dependent Cl - channel. The most frequent mutation, F508del, leads to the synthesis of a prematurely degraded, otherwise partially functional protein. CFTR is expressed in many epithelia, with major consequences in the airways of patients with CF, characterized by both fluid transport abnormalities and persistent inflammatory responses. The relationship between the acute phase of inflammation and the expression of wild type (WT) CFTR or F508del-CFTR is poorly understood. The aim of the present study was to investigate this effect. The results show that 10 min exposure to TNF-alpha (0.5-50ng/ml) of F508del-CFTR-transfected HeLa cells and human bronchial cells expressing F508del-CFTR in primary culture (HBE) leads to the maturation of F508del-CFTR and induces CFTR chloride currents. The enhanced CFTR expression and function upon TNFα is sustained, in HBE cells, for at least 24 h. The underlying mechanism of action involves a protein kinase C (PKC) signaling pathway, and occurs through insertion of vesicles containing F508del-CFTR to the plasma membrane, with TNFα behaving as a corrector molecule. In conclusion, a novel and unexpected action of TNFα has been discovered and points to the importance of systematic studies on the roles of inflammatory mediators in the maturation of abnormally folded proteins in general and in the context of CF in particular. PMID:26594334

  11. A review on Balanites aegyptiaca Del (desert date): phytochemical constituents, traditional uses, and pharmacological activity

    PubMed Central

    Chothani, Daya L.; Vaghasiya, H. U.

    2011-01-01

    Balanites aegyptiaca Del. (Zygophyllaceae), known as ‘desert date,’ is spiny shrub or tree up to l0 m tall, widely distributed in dry land areas of Africa and South Asia. It is traditionally used in treatment of various ailments i.e. jaundice, intestinal worm infection, wounds, malaria, syphilis, epilepsy, dysentery, constipation, diarrhea, hemorrhoid, stomach aches, asthma, and fever. It contains protein, lipid, carbohydrate, alkaloid, saponin, flavonoid, and organic acid. Present review summarizes the traditional claims, phytochemistry, and pharmacology of B. aegyptiaca Del reported in scientific literature. PMID:22096319

  12. Parental origin of de novo chromosome 9 deletions in del(9p) syndrome

    SciTech Connect

    Micale, M.A.; Haren, J.M.; Conroy, J.M.

    1995-05-22

    Parental origin of de novo deletions in the short arm of chromosome 9 in patients with a clinical diagnosis of del(9p) syndrome was assessed in 13 patients using polymerase chain reaction (PCR) analysis of highly polymorphic dinucleotide repeat microsatellite markers located in the putative deleted region. The deletion was found to be of paternal origin in 9 cases and of maternal origin in the remaining 4 cases, suggesting that the molecular event resulting in the deletion occurs in both male and female gametogenesis and that genomic imprinting does not appear to play a role in the pathogenesis of del(9p) syndrome. 22 refs., 1 fig.

  13. A review on Balanites aegyptiaca Del (desert date): phytochemical constituents, traditional uses, and pharmacological activity.

    PubMed

    Chothani, Daya L; Vaghasiya, H U

    2011-01-01

    Balanites aegyptiaca Del. (Zygophyllaceae), known as 'desert date,' is spiny shrub or tree up to l0 m tall, widely distributed in dry land areas of Africa and South Asia. It is traditionally used in treatment of various ailments i.e. jaundice, intestinal worm infection, wounds, malaria, syphilis, epilepsy, dysentery, constipation, diarrhea, hemorrhoid, stomach aches, asthma, and fever. It contains protein, lipid, carbohydrate, alkaloid, saponin, flavonoid, and organic acid. Present review summarizes the traditional claims, phytochemistry, and pharmacology of B. aegyptiaca Del reported in scientific literature. PMID:22096319

  14. First Case Report of EX3del4765 Mutation in PAH Gene in Asian Population

    PubMed Central

    Soltani, Ziba; Karami, Fatemeh; Yassaee, Vahidreza; Hashemi Gorji, Feyzollah; Talebzadeh, Mahdieh; Miryounesi, Mohammad

    2016-01-01

    Introduction: Phenylketonuria (PKU) is an autosomal recessive inborn error of phenylalanine metabolism, which is caused by mutation in phenylalanine hydroxylase (PAH) gene. Most of the PAH mutations are missense mutations (67%), which are followed by small or large deletions (13%). Case Presentation: We reported a patient with classic PKU and his parents harboring a large deletion in exon 3 (EX3del4765) of PAH gene. This is the first case report of EX3del4765 in Asian patients with PKU. Conclusions: This finding may help improve early detection, differential diagnosis, genetic counseling, and even treatment of patients with PKU.

  15. Resultado negativo de prueba del VPH es mejor predictor de riesgo bajo de cáncer de cuello uterino

    Cancer.gov

    De acuerdo con un estudio en el que participaron más de un millón de mujeres, los investigadores del NCI han determinado que el resultado negativo de una prueba para la detección del VPH proporciona mayor certeza o seguridad frente a riesgos futuros de cá

  16. Development of EST-based SNP and InDel markers and their utilization in tetraploid cotton genetic mapping

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Expressed sequence tags (ESTs) were analyzed in silico in order to identify single nucleotide polymorphisms (SNPs) and insertion-deletion polymorphisms (InDels) in cotton. A total of 1349 EST-based SNP and InDel markers were developed by comparing ESTs between Gossypium hirsutum and G. barbadense, m...

  17. 75 FR 44720 - Safety Zone; Live-Fire Gun Exercise, M/V Del Monte, James River, VA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-29

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Live-Fire Gun Exercise, M/V Del Monte... specified waters of the James River to protect mariners from the hazards associated with live fire and... conduct a live fire and explosive training event onboard the M/V Del Monte in the vicinity of the...

  18. DELIVERING TIMELY AIR QUALITY, TRAFFIC, AND WEATHER INFORMATION TO YOUR COMMUNITY/THE PASO DEL NORTE ENVIRONMENTAL MONITORING PROJECT

    EPA Science Inventory

    EPA has developed a technology transfer handbook for the EMPACT Paso del Norte Project. The EMPACT Paso del Norte Environmental Monitoring Project is a mobile vehicle emissions project that involves the international community of El Paso, TX; Sundland Park, NM; and Juarez, Mexico...

  19. Plan Multinacional de Educacion del Adulto (Multinational Plan for Adult Education).

    ERIC Educational Resources Information Center

    Eduplan Informa, 1971

    1971-01-01

    This document contains part of the final report from the first meeting of the Inter-American Council on Education, Science, and Culture, held in Vina del Mar, Chile, in 1970. The report presents general policy and guidelines which should be followed in the establishment of adult elementary education programs. The general discussion covers literacy…

  20. Quantum tunneling from a high dimensional Gödel black hole

    NASA Astrophysics Data System (ADS)

    Li, Hui-Ling; Feng, Zhong-Wen; Zu, Xiao-Tao

    2016-02-01

    Considering the quantum gravity effect, we investigate the quantum tunneling from a high dimensional Kerr-Gödel black hole using a generalized Dirac equation. As a result, revised tunneling probability is obtained, and the corrected Hawking temperature is also presented.

  1. Informe del NCI y los CDC sobre el tabaco sin humo

    Cancer.gov

    El primer informe sobre el consumo mundial del tabaco sin humo y sus consecuencias en la salud pública reveló que más de 300 millones de personas en al menos 70 países usan estos productos dañinos.

  2. Advances in optical technologies at Pontificia Universidad Católica del Perú

    NASA Astrophysics Data System (ADS)

    Baldwin, Guillermo; Asmad, Miguel; Romero, Sandra; Gonzales, Franco; Gálvez, Gonzalo; Sánchez, Rubén; Córdova, Darwin

    2011-05-01

    In this work, it is shown a panoramically view of advances and works on fundamental optical technology developed and Physics Section at Pontificia Universidad Católica del Perú PUCP in Lima Peru. This includes works in, precision optics manufacturing, optical testing, and optical design and simulation and also in optical thin film evaporation and its design techniques

  3. Urban Impact of Dissolved Metals in the Paso del Norte Segment of the Rio Grande

    ERIC Educational Resources Information Center

    Freiwan, Sumayeh Ahmad

    2013-01-01

    The Paso del Norte segment of the Rio Grande experiences two seasons per year; the (wet) irrigation season and the (dry) non-irrigation season. The goal of this study was to improve the understanding of occurrence and contribution of dissolved metals in this region during the non-irrigation season. The objectives of this study were to (1) evaluate

  4. Control del dolor: Apoyo para las personas con cáncer

    Cancer.gov

    Contiene información sobre las medicinas contra el dolor para pacientes con cáncer, los planes para controlarlo, cómo hablar con su equipo de atención médica sobre el dolor que usted siente y qué hacer para controlar los efectos físicos y emocionales del

  5. Tratamiento del cáncer sin daño al corazón

    Cancer.gov

    Investigadores de los campos de oncología y de cardiología están trabajando para encontrar formas de impedir, manejar y posiblemente aun revertir los efectos secundarios cardiovasculares de ciertas terapias del cáncer.

  6. Use of del Nido Cardioplegia for Adult Cardiac Surgery at the Cleveland Clinic: Perfusion Implications

    PubMed Central

    Kim, Kuna; Ball, Clifford; Grady, Patrick; Mick, Stephanie

    2014-01-01

    Abstract: Cardiac arrest by cardioplegia provides a reproducible and safe method to induce and maintain electromechanical cardiac quiescence. Techniques of intraoperative myocardial protection are constantly evolving. For the past three decades, modified Buckberg cardioplegia solution has been used for adult cardiac surgery at the Cleveland Clinic. This formulation serves as the crystalloid component, which is delivered 4:1 with oxygenated patient’s blood to crystalloid. Meanwhile, our use of the del Nido cardioplegia solution in adult patients, heretofore primarily used in pediatric cardiac surgical centers, has been increasing over the past several years. Single-dose, cold blood del Nido cardioplegia can be delivered antegrade if the duration of the operation will be limited and if there is no significant coronary artery disease or aortic insufficiency that would limit the distribution of cardioplegia. The addition of del Nido cardioplegia to our cardioplegia armamentarium allows us to customize our myocardial protection strategies for different surgical needs. This article aims to provide information on technical aspects of del Nido cardioplegia in adult cardiac surgery and its use at the Cleveland Clinic in the adult surgical population. PMID:26357803

  7. Urban Impact of Dissolved Metals in the Paso del Norte Segment of the Rio Grande

    ERIC Educational Resources Information Center

    Freiwan, Sumayeh Ahmad

    2013-01-01

    The Paso del Norte segment of the Rio Grande experiences two seasons per year; the (wet) irrigation season and the (dry) non-irrigation season. The goal of this study was to improve the understanding of occurrence and contribution of dissolved metals in this region during the non-irrigation season. The objectives of this study were to (1) evaluate…

  8. Functional Rescue of F508del-CFTR Using Small Molecule Correctors

    PubMed Central

    Molinski, Steven; Eckford, Paul D. W.; Pasyk, Stan; Ahmadi, Saumel; Chin, Stephanie; Bear, Christine E.

    2012-01-01

    High-throughput screens for small molecules that are effective in “correcting” the functional expression of F508del-CFTR have yielded several promising hits. Two such compounds are currently in clinical trial. Despite this success, it is clear that further advances will be required in order to restore 50% or greater of wild-type CFTR function to the airways of patients harboring the F508del-CFTR protein. Progress will be enhanced by our better understanding of the molecular and cellular defects caused by the F508del mutation, present in 90% of CF patients. The goal of this chapter is to review the current understanding of defects caused by F508del in the CFTR protein and in CFTR-mediated interactions important for its biosynthesis, trafficking, channel function, and stability at the cell surface. Finally, we will discuss the gaps in our knowledge regarding the mechanism of action of existing correctors, the unmet need to discover compounds which restore proper CFTR structure and function in CF affected tissues and new strategies for therapy development. PMID:23055971

  9. ATMOSPHERIC VOLATILE ORGANIC COMPOUND MEASUREMENTS DURING THE 1996 PASO DEL NORTE OZONE STUDY

    EPA Science Inventory

    Ambient air VOC samples were collected at surface air quality monitoring sites, near sources of interest, and aloft on the US (El Paso) and Mexican (Ciudad Juarez) side of the border during a six-week period of the 1996 Paso del Norte Ozone Study. Samples were collected at five...

  10. Conserved charges and thermodynamics of the spinning Gödel black hole.

    PubMed

    Barnich, Glenn; Compère, Geoffrey

    2005-07-15

    We compute the mass, angular momenta, and charge of the Gödel-type rotating black hole solution to five-dimensional minimal supergravity. A generalized Smarr formula is derived, and the first law of thermodynamics is verified. The computation rests on a new approach to conserved charges in gauge theories that allows for their computation at finite radius. PMID:16090734

  11. Shed Some Light on the Subject: Teaching Ramon del Valle-Inclan's "Luces de bohemia"

    ERIC Educational Resources Information Center

    Parker, Jason Thomas

    2011-01-01

    This essay seeks to provide parallel and interchangeable approaches to teaching Ramon del Valle-Inclan's challenging play "Luces de bohemia". A greater understanding of the cultural and mental frameworks of the early twentieth-century Spanish spectator will permit students to penetrate the dense intertextuality that characterizes Valle's…

  12. The c.657del5 variant in the NBN gene predisposes to pancreatic cancer.

    PubMed

    Borecka, Marianna; Zemankova, Petra; Lhota, Filip; Soukupova, Jana; Kleiblova, Petra; Vocka, Michal; Soucek, Pavel; Ticha, Ivana; Kleibl, Zdenek; Janatova, Marketa

    2016-08-10

    Pancreatic ductal adenocarcinoma (PDAC) is the sixth most frequent cancer type in the Czech Republic with a poor prognosis that could be improved by an early detection and subsequent surgical treatment combined with chemotherapy. Genetic factors play an important role in PDAC risk. We previously identified one PDAC patient harboring the Slavic founder deleterious mutation c.657del5 in the NBN gene, using a panel next-generation sequencing (NGS). A subsequent analysis of 241 unselected PDAC patients revealed other mutation carriers. The overall frequency of c.657del5 in unselected PDAC patients (5/241; 2.07%) significantly differed from that in non-cancer controls (2/915; 0.2%; P=0.006). The result indicates that the NBN c.657del5 variant represents a novel PDAC-susceptibility allele increasing PDAC risk (OR=9.7; 95% CI: 1.9 to 50.2). The increased risk of PDAC in follow-up recommendations for NBN mutation carriers should be considered if other studies also confirm an increased frequency of c.657del5 carriers in PDAC patients from other populations. PMID:27150568

  13. REPRODUCTIVE RHYTHMICITY OF THE ATHERINID FISH, 'COLPICHTHYS REGIS', FROM ESTERO DEL SOLDADO, SONORA, MEXICO

    EPA Science Inventory

    The reproductive rhythmicity of the false grunion, Colpichthys regis, was observed in the Estero del Soldado, Mexico during October 1982 through January 1983. Spawning runs occurred at approximately 2-week intervals during daytime high tides. These high tides coincided with new a...

  14. Dolores Del Rio, the First "Latin Invasion", and Hollywood's Transition to Sound

    ERIC Educational Resources Information Center

    Beltran, Mary

    2005-01-01

    The career and promotion of Mexican actress Dolores Del Rio as a case study of how Hollywood's shift to sound film affected Latino and Latina actors is examined. It reveals the way in which the starring opportunities for Latinos dwindled when accent and language increasingly marked them as nonwhite in the 1930s in the talkie films.

  15. Fermions tunnelling from 5D general rotating charged Gödel black hole

    NASA Astrophysics Data System (ADS)

    Song, Shi-Xiong; Huang, Jiang; Ren, Ji-Rong

    2011-01-01

    Using the tunneling method we derive the Hawking temperature of the nonextremal rotating charged black hole in the Gödel universe of five-dimensional minimal supergravity theory found by Wu. We successfully recovered the tunneling probability of charged Dirac particles and the expected Hawking temperature of the black hole, which is exactly consistent with that obtained by other methods.

  16. Exploración del Sistema Solar -- Una mirada hacia el futuro - Duration: 30 seconds.

    NASA Video Gallery

    ¿Piensas que ya sabemos todo acerca de nuestro sistema solar? La realidad es que apenas hemos comenzado con lo que hay para conocer. Únete a la NASA, en el envío de misiones a los confines del sist...

  17. Calcio y la prevención del cáncer

    Cancer.gov

    Hoja informativa que resume los resultados de estudios sobre el calcio y la prevención del cáncer. Incluye información sobre las recomendaciones dietéticas para calcio y la cantidad de calcio en los alimentos y en complementos de calcio.

  18. Dropouts, Stopouts, Optouts at Del Mar College: Spring 1991. Report of a Joint Research Project.

    ERIC Educational Resources Information Center

    Luckie, Jo Ann I.; Bonham, L. Adrianne

    A research project investigated 2,313 persons who attended Del Mar College (Texas) during fall 1990 but did not enroll for spring 1991. Four sets of data were collected: (1) limited demographic information on the total student body; (2) demographic information drawn from school records to describe all nonreturnees; (3) demographic information…

  19. 33 CFR 334.110 - Delaware Bay off Cape Henlopen, Del.; naval restricted area.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ....110 Delaware Bay off Cape Henlopen, Del.; naval restricted area. (a) The area. Beginning at a point on the south shore of Delaware Bay at longitude 75°06′12″; thence to latitude 38°47′25″, longitude 75°06... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Delaware Bay off Cape...

  20. 33 CFR 334.110 - Delaware Bay off Cape Henlopen, Del.; naval restricted area.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ....110 Delaware Bay off Cape Henlopen, Del.; naval restricted area. (a) The area. Beginning at a point on the south shore of Delaware Bay at longitude 75°06′12″; thence to latitude 38°47′25″, longitude 75°06... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Delaware Bay off Cape...