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Sample records for toxicidad local del

  1. Study of the Local Horizon. (Spanish Title: Estudio del Horizonte Local.) Estudo do Horizonte Local

    NASA Astrophysics Data System (ADS)

    Ros, Rosa M.

    2009-12-01

    The study of the horizon is fundamental to easy the first observations of the students at any education center. A simple model, to be developed in each center, allows to easy the study and comprehension of the rudiments of astronomy. The constructed model is presented in turn as a simple equatorial clock, other models (horizontal and vertical) may be constructed starting from it. El estudio del horizonte es fundamental para poder facilitar las primeras observaciones de los alumnos en un centro educativo. Un simple modelo, que debe realizarse para cada centro, nos permite facilitar el estudio y la comprensión de los primeros rudimentos astronómicos. El modelo construido se presenta a su vez como un sencillo modelo de reloj ecuatorial y a partir de él se pueden construir otros modelos (horizontal y vertical). O estudo do horizonte é fundamental para facilitar as primeiras observações dos alunos num centro educativo. Um modelo simples, que deve ser feito para cada centro, permite facilitar o estudo e a compreensão dos primeiros rudimentos astronômicos. O modelo construído apresenta-se, por sua vez, como um modelo simples de relógio equatorial e a partir dele pode-se construir outros modelos (horizontal e vertical)

  2. Focal Mechanisms for Local Earthquakes within a Rapidly Deforming Rhyolitic Magma System, Laguna del Maule, Chile

    NASA Astrophysics Data System (ADS)

    Peterson, D. E.; Keranen, K. M.; Cardona, C.; Thurber, C. H.; Singer, B. S.

    2015-12-01

    Large shallow rhyolitic magma systems like the one underlying the Laguna del Maule Volcanic Field (LdM) atop the Southern Andes, Chile, that comprises the largest concentration of rhyolitic lava and tephra younger than 20 ka at earth's surface, are capable of producing modest to very large explosive eruptions. Moreover, LdM is currently exhibiting magma migration, reservoir growth, and crustal deformation at rates higher than any volcano that is not actively erupting. The long-term build-up of a large silicic magmatic system toward an eruption has yet to be monitored, therefore, precursory phenomena are poorly understood. In January of 2015, 12 broadband, 3-component seismometers were installed at LdM to detect local microearthquakes and tele-seismic events with the goals of determining the migration paths of fluids as well as the boundaries of the magma chamber beneath LdM. These stations complement the 6 permanent stations installed by the Southern Andes Volcano Observatory in 2011. Focal mechanisms were calculated using FOCMEC (Snoke et al., 1984) and P-wave first motions for local events occurring between January and March of 2015 using these 18 broadband stations. Results from six of the largest local events indicate a mixture of normal and reverse faulting at shallow (<10 km) depths surrounding the lake. This may be associated with the opening of fractures to accommodate rising magma in the subsurface and/or stresses induced by the rapid deformation. Two of these events occurred near the center of maximum deformation where seismic swarms have previously been identified. Focal mechanisms from smaller magnitude events will be calculated to better delineate subsurface structure. Source mechanisms will be refined using P-S amplitude ratios and full waveform inversion.

  3. Paleoenvironmental reconstruction of the coastal Monte Léon and Santa Cruz formations (Early Miocene) at Rincón del Buque, Southern Patagonia: A revisited locality

    NASA Astrophysics Data System (ADS)

    Raigemborn, M. Sol; Matheos, Sergio D.; Krapovickas, Verónica; Vizcaíno, Sergio F.; Bargo, M. Susana; Kay, Richard F.; Fernicola, Juan C.; Zapata, Luciano

    2015-07-01

    Sedimentological, ichnological and paleontological analyses of the Early Miocene uppermost Monte León Formation and the lower part of the Santa Cruz Formation were carried out in Rincón del Buque (RDB), a fossiliferous locality north of Río Coyle in Santa Cruz Province, Patagonia, Argentina. This locality is of special importance because it contains the basal contact between the Monte Léon (MLF) and the Santa Cruz (SCF) formations and because it preserves a rich fossil assemblage of marine invertebrates and marine trace fossils, and terrestrial vertebrates and plants, which has not been extensively studied. A ˜90 m-thick section of the MLF and the SCF that crops out at RDB was selected for this study. Eleven facies associations (FA) are described, which are, from base to top: subtidal-intertidal deposits with Crassotrea orbignyi and bioturbation of the Skolithos-Cruziana ichnofacies (FA1); tidal creek deposits with terrestrial fossil mammals and Ophiomorpha isp. burrows (FA2); tidal flat deposits with Glossifungites ichnofacies (FA3); deposits of tidal channels (FA4) and tidal sand flats (FA5) both with and impoverish Skolithos ichnofacies associated; marsh deposits (FA6); tidal point bar deposits recording a depauperate mixture of both the Skolithos and Cruziana ichnofacies (FA7); fluvial channel deposits (FA8); fluvial point bar deposits (FA9); floodplain deposits (FA10); and pyroclastic and volcaniclastic deposits of the floodplain where terrestrial fossil mammal remains occur (FA11). The transition of the MLF-SCF at RDB reflects a changing depositional environment from the outer part of an estuary (FA1) through the central (FA2-6) to inner part of a tide-dominated estuary (FA7). Finally a fluvial system occurs with single channels of relatively low energy and low sinuosity enclosed by a broad, low-energy floodplain dominated by partially edaphized ash-fall, sheet-flood, and overbank deposits (FA8-11). Pyroclastic and volcaniclastic materials throughout the

  4. Arroyo del Vizcaíno, Uruguay: a fossil-rich 30-ka-old megafaunal locality with cut-marked bones

    PubMed Central

    Fariña, Richard A.; Tambusso, P. Sebastián; Varela, Luciano; Czerwonogora, Ada; Di Giacomo, Mariana; Musso, Marcos; Bracco, Roberto; Gascue, Andrés

    2014-01-01

    Human–megafauna interaction in the Americas has great scientific and ethical interest because of its implications on Pleistocene extinction. The Arroyo del Vizcaíno site near Sauce, Uruguay has already yielded over 1000 bones belonging to at least 27 individuals, mostly of the giant sloth Lestodon. The assemblage shows some taphonomic features suggestive of human presence, such as a mortality profile dominated by prime adults and little evidence of major fluvial transport. In addition, several bones present deep, asymmetrical, microstriated, sharp and shouldered marks similar to those produced by human stone tools. A few possible lithic elements have also been collected, one of which has the shape of a scraper and micropolish consistent with usage on dry hide. However, the radiocarbon age of the site is unexpectedly old (between 27 and 30 thousand years ago), and thus may be important for understanding the timing of the peopling of America. PMID:24258717

  5. Arroyo del Vizcaíno, Uruguay: a fossil-rich 30-ka-old megafaunal locality with cut-marked bones.

    PubMed

    Fariña, Richard A; Tambusso, P Sebastián; Varela, Luciano; Czerwonogora, Ada; Di Giacomo, Mariana; Musso, Marcos; Bracco, Roberto; Gascue, Andrés

    2014-01-01

    Human-megafauna interaction in the Americas has great scientific and ethical interest because of its implications on Pleistocene extinction. The Arroyo del Vizcaíno site near Sauce, Uruguay has already yielded over 1000 bones belonging to at least 27 individuals, mostly of the giant sloth Lestodon. The assemblage shows some taphonomic features suggestive of human presence, such as a mortality profile dominated by prime adults and little evidence of major fluvial transport. In addition, several bones present deep, asymmetrical, microstriated, sharp and shouldered marks similar to those produced by human stone tools. A few possible lithic elements have also been collected, one of which has the shape of a scraper and micropolish consistent with usage on dry hide. However, the radiocarbon age of the site is unexpectedly old (between 27 and 30 thousand years ago), and thus may be important for understanding the timing of the peopling of America. PMID:24258717

  6. Making COD statistics useful for public health at local level in the city of Cape Town: utilidad para la salud pública a nivel local en Ciudad del Cabo.

    PubMed Central

    Bradshaw, Debbie; Groenewald, Pamela; Bourne, David E.; Mahomed, Hassan; Nojilana, Beatrice; Daniels, Johan; Nixon, Jo

    2006-01-01

    OBJECTIVE: To review the quality of the coding of the cause of death (COD) statistics and assess the mortality information needs of the City of Cape Town. METHODS: Using an action research approach, a study was set up to investigate the quality of COD information, the accuracy of COD coding and consistency of coding practices in the larger health subdistricts. Mortality information needs and the best way of presenting the statistics to assist health managers were explored. FINDINGS: Useful information was contained in 75% of death certificates, but nearly 60% had only a single cause certified; 55% of forms were coded accurately. Disagreement was mainly because routine coders coded the immediate instead of the underlying COD. An abridged classification of COD, based on causes of public health importance, prevalent causes and selected combinations of diseases was implemented with training on underlying cause. Analysis of the 2001 data identified the leading causes of death and premature mortality and illustrated striking differences in the disease burden and profile between health subdistricts. CONCLUSION: Action research is particularly useful for improving information systems and revealed the need to standardize the coding practice to identify underlying cause. The specificity of the full ICD classification is beyond the level of detail on the death certificates currently available. An abridged classification for coding provides a practical tool appropriate for local level public health surveillance. Attention to the presentation of COD statistics is important to enable the data to inform decision-makers. PMID:16583080

  7. DelPhi: a comprehensive suite for DelPhi software and associated resources

    PubMed Central

    2012-01-01

    Background Accurate modeling of electrostatic potential and corresponding energies becomes increasingly important for understanding properties of biological macromolecules and their complexes. However, this is not an easy task due to the irregular shape of biological entities and the presence of water and mobile ions. Results Here we report a comprehensive suite for the well-known Poisson-Boltzmann solver, DelPhi, enriched with additional features to facilitate DelPhi usage. The suite allows for easy download of both DelPhi executable files and source code along with a makefile for local installations. The users can obtain the DelPhi manual and parameter files required for the corresponding investigation. Non-experienced researchers can download examples containing all necessary data to carry out DelPhi runs on a set of selected examples illustrating various DelPhi features and demonstrating DelPhi’s accuracy against analytical solutions. Conclusions DelPhi suite offers not only the DelPhi executable and sources files, examples and parameter files, but also provides links to third party developed resources either utilizing DelPhi or providing plugins for DelPhi. In addition, the users and developers are offered a forum to share ideas, resolve issues, report bugs and seek help with respect to the DelPhi package. The resource is available free of charge for academic users from URL: http://compbio.clemson.edu/DelPhi.php. PMID:22583952

  8. Nevado del Huila, Columbia

    NASA Technical Reports Server (NTRS)

    2007-01-01

    Nevado del Huila Volcano in Colombia is actually a volcanic chain running north to south, capped by a glacier. With peaks ranging in height from 2,600 to 5,780 meters (8,530 to 18,960 feet), Nevado del Huila is a stratovolcano composed of alternating layers of hardened lava, solidified ash, and volcanic rocks. Its first recorded eruption occurred in the mid-sixteenth century. The long-dormant volcano erupted again in mid-April 2007. A few months before the eruption, the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on NASA's Terra satellite captured this image of Nevado del Huila, on February 23, 2007. In this image, the bright white area just east of the central summit is ice. Immediately west of the summit are bare rocks, appearing as blue-gray. West of those rocks, white reappears, but this patch of white results from clouds hovering in the nearby valley. In the east, the colors turn to brown (indicating bare rock) and bright green (indicating vegetation). ASTER photographed Nevado del Huila near the end of a long phase of quietude. On April 17, 2007, local authorities recorded seismic activity associated with rock fracturing on the volcano's central summit, according to the ReliefWeb Website. Activity intensified the following day with an eruption and mudflows, forcing thousands of nearby residents to evacuate. As the Associated Press reported, the eruption caused avalanches and floods that wiped away both houses and bridges. It marked the volcano's first recorded eruption since the Spanish colonized the area five centuries earlier. NASA image created by Jesse Allen, using data provided courtesy of the NASA/GSFC/MITI/ERSDAC/JAROS, and U.S./Japan ASTER Science Team.

  9. Local Toolkit

    Energy Science and Technology Software Center (ESTSC)

    2007-05-31

    The LOCAL Toolkit contains tools and libraries developed under the LLNL LOCAL LDRD project for managing and processing large unstructured data sets primrily from parallel numerical simulations, such as triangular, tetrahedral, and hexahedral meshes, point sets, and graphs. The tools have three main functionalities: cache-coherent, linear ordering of multidimensional data; lossy and lossless data compression optimized for different data types; and an out-of-core streaming I/O library with simple processing modules for unstructed data.

  10. Local Heroes.

    ERIC Educational Resources Information Center

    Uehling, Barbara

    1996-01-01

    As critics complain about higher education's shortcomings, trustees may need to communicate their institution's economic, cultural, and intellectual contributions to the local community. The most obvious and easily understood benefit is purchasing power, but it also contributes to small business growth, individual quality of life, the social,…

  11. Localized scleroderma.

    PubMed

    Kreuter, Alexander

    2012-01-01

    Localized scleroderma (also called morphea) is a term encompassing a spectrum of sclerotic autoimmune diseases that primarily affect the skin, but also might involve underlying structures such as the fat, fascia, muscle, and bones. Its exact pathogenesis is still unknown, but several trigger factors in genetically predisposed individuals might initially lead to an immunologically triggered release of pro-inflammatory cytokines, resulting in a profound dysregulation of the connective tissue metabolism and ultimately to induction of fibrosis. To date, there are no specific serological markers available for localized scleroderma. Within the last years, several validated clinical scores have been introduced as potential outcome measures for the disease. Given the rarity of localized scleroderma, only few evidence-based therapeutical treatment options exist. So far, the most robust data is available for ultraviolet A1 phototherapy in disease that is restricted to the skin, and methotrexate alone or in combination with systemic corticosteroids in more severe disease that additionally affects extracutaneous structures. This practical review summarizes relevant information on the epidemiology, pathogenesis, clinical subtypes and classifications, differential diagnoses, clinical scores and outcome measures, and current treatment strategies of localized scleroderma. PMID:22741933

  12. Local Research.

    ERIC Educational Resources Information Center

    Sommer, Robert

    1990-01-01

    Discusses the value of setting-specific research for action research in social psychology. Discusses the following concepts: (1) local variation; (2) seeing the general in the specific; (3) connectedness as the fundamental law of ecology; and (4) the value of field stations for community research. (JS)

  13. Local hyperdynamics.

    PubMed

    Kim, Soo Young; Perez, Danny; Voter, Arthur F

    2013-10-14

    We present a new formulation of the hyperdynamics method in which the biasing effect is local, making it suitable for large systems. In standard hyperdynamics, the requirement that the bias potential be zero everywhere on the dividing surface bounding the state has the consequence that as the system size increases the boost factor decays to unity, regardless of the form of the bias potential. In the new method, the bias force on each atom is obtained by differentiating a local bias energy that depends only on the coordinates of atoms within a finite range of this atom. This bias force is thus independent of the bias force in distant parts of the system, providing a method that gives a constant boost factor, independent of the system size. We demonstrate for some realistic atomistic systems that the method gives escape rates in excellent agreement with direct molecular dynamics simulations. PMID:24116606

  14. Interconexión de la Estación Astrofísica de Bosque Alegre y la red local de datos del Observatorio Astronómico de Córdoba

    NASA Astrophysics Data System (ADS)

    Nicotra, M. A.; Anun, S.; Montes, M.; Goldes, G.; Carranza, G.

    We describe the outlines of a project for the interconnection between the Astrophysical Station of Bosque Alegre and the wide area network of the University of Córdoba. The Astrophysical Station is located 38.55 km (23.96 milles) from the Observatory of Córdoba. This location is suitable for radio links in the range of centimeters wavelenghts. In the last years, Spread-Spectrum technology equipments has become popular. Spread-Spectrum signals, contrary to narrow band radio signals, operates within a widthband 20 to 200 times broader than the widthband of the modulated information. Signals are modulated by special spreading codes, in such a way that emulates noisy signals. These codes are known under the generic designation of pseudo-random or pseudo-noise. In addition, the wide band is correlated with a low power density in the emitted signals. Spread-Spectrum equipment links are stable, exhibits low interferences with conventional radio transmitters, and their commercial prices are remarkably lower than those for the conventional microwave devices. Data links are compliant with Ethernet protocol networks and operates with data tramsmition rates up to 4 Mbits per second. The described equipment will enable the access to full-Internet services for visitor astronomers in Bosque Alegre. Also, it will be possible fast transfer for the observational data from telescope to computers in the local area network at Córdoba. This project must be considered as the second stage of another wide purpose project, which has the main purpose in transforming the Bosque Alegre Station as a fully robotic station controlled from the computational center at the Observatory in Cordoba. The advantages of robotic telescopes has recently been the subject of several discussions. However, it is now widely accepted that an automatic station enables some important options in the use of the astronomical instruments, such us the possibility of performing parallel programs, one of which is

  15. Preguntas y respuestas acerca del Estudio del

    Cancer.gov

    El Estudio del Tamoxifeno y Raloxifeno (STAR, por sus siglas en ingls) es un estudio clnico (un estudio de investigacin conducido con voluntarios) diseado para ver cómo el medicamento raloxifeno (Evista) se compara con el medicamento tamoxifeno (Nolvadex)

  16. Quantum Locality?

    NASA Astrophysics Data System (ADS)

    Stapp, Henry P.

    2012-05-01

    , in response to Griffiths' challenge, why a putative proof of locality that he has described is flawed.

  17. Calidad de Imagen del Telescopio UNAM212

    NASA Astrophysics Data System (ADS)

    Cobos, F. J.; Teiada de Vargas, C.

    1987-05-01

    El telescopio UNAM2l2, del Observatorio Astronómico Nacional, situado en la Sierra de San Pedro Mártir (Baja California, México), cumplira en un futuro muy cercano siete años de uso para fines de investigación astronómica. Aunque en este tiempo no se ha efectuado un estudio sistemático acerca de su comportamiento óptico y de los factores que influyen en la calidad de las imágenes, se han realizado pruebas diversas, estudios parciales y reuniones especificas, cuyos resultados no siempre se han difundido ampliamente y generalmente no se han presentado por escrito. Es por ello que hemos creido necesario intentar una recopilación de la información existente para poder con ella establecer un diagnóstjco que, aunque no sea definitivo, sirva de base para futuros trabajos tendientes a optimizar el comportamiento óptico del telescopio. Es evidente que un buen número de las conclusiones que se presentan son resultado del trabajo de muchas personas ó de esfuerzos colectivos. Asimismo, hemos tratado de localizar información bibliográfica que pueda ser de utilidad. Nuestro objetivo primordial ha consistido en centrarnos en la óptica del telescopio y su calidad, pero también se han considerado otros aspectos que puedan afectar las imágenes obtenidas tales como: celda del primario, `seeing' local y externo, flexiones posibles en la estructura mecánica del telescopio, etc.

  18. Quantum Locality?

    SciTech Connect

    Stapp, Henry

    2011-11-10

    vagaries that he cites do not upset the proof in question. It is show here in detail why the precise statement of this theorem justifies the specified application of CQT. It is also shown, in response to his challenge, why a putative proof of locality that he has proposed is not valid.

  19. Il problema del litio.

    NASA Astrophysics Data System (ADS)

    D'Antona, F.

    1995-03-01

    Contents: 1. Introduzione. 2. La nucleosintesi del Big Bang. 3. Il litio nelle stelle di popolazione II. 4. I modelli stellari standard. 5. Il litio negli ammassi aperti. 6. Meccanismi di distruzione "non standard". 7. I modelli non-standard applicati alla popolazione II. 8. L'evoluzione Galattica del litio. 9. Quali stelle producono litio? 10. Il litio come elemento chiave per dare un nome agli oggetti stellari più minuscoli. 11. Conclusioni.

  20. Espectroscopia del Cometa Halley

    NASA Astrophysics Data System (ADS)

    Naranjo, O.; Fuenmayor, F.; Ferrin, L.; Bulka, P.; Mendoza, C.

    1987-05-01

    Se reportan observaciones espectroscópicas del cometa Halley. Los espectros fueron tomados usando el espectrógrafo del telescopio reflector de 1 metro del Observatorio Nacional de Venezuela. Se utilizó óptica azul, con una red de difracción de 600 lineas/min, obteniéndose una dispersión de 74.2 A/mm y una resolución de 2.5 A, en el rango espectral de 3500 a 6500 A. Seis placas fueron tomadas con emulsión IIa-O y dos con IIa-D. Los tiempos de exposición fueron entre 10 y 150 minutos. El cometa se encontraba entre 0.70 y 1.04 UA del Sol, y entre 1.28 y 0.73 UA de la Tierra. Las emisiones más prominentes en el espectro, son las del CN, C2, y C3. Otras emisiones detectadas corresponden a CH, NH2 y Na. Los espectros muestran un fuerte continuo, indicando un contenido significativo de polvo. Se detectó mayor intensidad del contínuo, en la dirección anti solar, lo cual es evidencia de la cola de polvo.

  1. Del Mod at a Glance, Volume 3. 1973-1974 Annual Report for the Del Mod System.

    ERIC Educational Resources Information Center

    Bolig, John R.

    A synopsis of the 1973-74 annual report for the Del Mod System is presented. The activities described were conducted by the University of Delaware, Delaware State College, Delaware Technical and Community College, and the Department of Public Instruction. Activities of field agents, several local district projects, and individual teacher grants…

  2. Local perturbations perturb—exponentially–locally

    SciTech Connect

    De Roeck, W. Schütz, M.

    2015-06-15

    We elaborate on the principle that for gapped quantum spin systems with local interaction, “local perturbations [in the Hamiltonian] perturb locally [the groundstate].” This principle was established by Bachmann et al. [Commun. Math. Phys. 309, 835–871 (2012)], relying on the “spectral flow technique” or “quasi-adiabatic continuation” [M. B. Hastings, Phys. Rev. B 69, 104431 (2004)] to obtain locality estimates with sub-exponential decay in the distance to the spatial support of the perturbation. We use ideas of Hamza et al. [J. Math. Phys. 50, 095213 (2009)] to obtain similarly a transformation between gapped eigenvectors and their perturbations that is local with exponential decay. This allows to improve locality bounds on the effect of perturbations on the low lying states in certain gapped models with a unique “bulk ground state” or “topological quantum order.” We also give some estimate on the exponential decay of correlations in models with impurities where some relevant correlations decay faster than one would naively infer from the global gap of the system, as one also expects in disordered systems with a localized groundstate.

  3. Atlas del Genoma del Cáncer: Antecedentes

    Cancer.gov

    El Atlas del Genoma del Cáncer es una iniciativa de los Institutos Nacionales de la Salud (NIH) para crear mapas multidimensionales completos de los cambios genómicos clave en los tipos y subtipos principales de cáncer.

  4. Localized Prostate Cancer

    MedlinePlus

    ... a decision aid for men with clinically localized prostate cancer (available at http://effectivehealthcare.ahrq.gov/prostate_da) ... A Decision Aid for Men With Clinically Localized Prostate Cancer Page 1 of 24 Introduction Men with clinically ...

  5. Temporal Non-locality

    NASA Astrophysics Data System (ADS)

    Filk, Thomas

    2013-04-01

    In this article I investigate several possibilities to define the concept of "temporal non-locality" within the standard framework of quantum theory. In particular, I analyze the notions of "temporally non-local states", "temporally non-local events" and "temporally non-local observables". The idea of temporally non-local events is already inherent in the standard formalism of quantum mechanics, and Basil Hiley recently defined an operator in order to measure the degree of such a temporal non-locality. The concept of temporally non-local states enters as soon as "clock-representing states" are introduced in the context of special and general relativity. It is discussed in which way temporally non-local measurements may find an interesting application for experiments which test temporal versions of Bell inequalities.

  6. Time to Go Local!

    MedlinePlus

    ... Bar Home Current Issue Past Issues Time to Go Local! Past Issues / Winter 2007 Table of Contents ... MedlinePlus.gov health topic pages, you will find "Go Local" links that take you to information about ...

  7. Ácaros del mango

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Los ácaros constituyen un grupo abundante y diverso que ocupa diferentes hábitats en árboles frutales y la estructura y disposición del follaje y ramas del mango, contribuyen significativamente a que se presente gran diversidad de ácaros benéficos y dañinos asociados a esta especie frutal. En Colomb...

  8. Local network assessment

    NASA Astrophysics Data System (ADS)

    Glen, D. V.

    1985-04-01

    Local networks, related standards activities of the Institute of Electrical and Electronics Engineers the American National Standards Institute and other elements are presented. These elements include: (1) technology choices such as topology, transmission media, and access protocols; (2) descriptions of standards for the 802 local area networks (LAN's); high speed local networks (HSLN's) and military specification local networks; and (3) intra- and internetworking using bridges and gateways with protocols Interconnection (OSI) reference model. The convergence of LAN/PBX technology is also described.

  9. Learning from Software Localization.

    ERIC Educational Resources Information Center

    Guo, She-Sen

    2003-01-01

    Localization is the process of adapting a product to meet the language, cultural and other requirements of a specific target environment or market. This article describes ways in which software localization impacts upon curriculum, and discusses what students will learn from software localization. (AEF)

  10. Integrated program designed for local governments.

    PubMed

    1993-01-01

    Local Philippine governments are required under the 1991 Local Government Code to plan and manage their own health and nutrition programs. In response to their requests, the Municipal Integrated Nutrition Program (MINP) is being developed. This program will integrate the local efforts of the following national nutrition programs: the Teacher-Child-Parent Approach of the Department of Education, Culture, and Sports; the Community-Based Planning and Management of Nutrition Programs of the Department of Health; the Early Childhood Enrichment Program of the Department of Social welfare and Development; and the Bio-Intensive Gardening for Home/Community Food Security of the Department of Agriculture. The Nutrition Center of the Philippines (NCP) has assisted in the development, testing, and evaluation of the MINP. In 1993, MINP models will begin in 1 or 2 barangays in Carmen, Cebu; Hilongos, Leyte; and Dapitan City in Zamboanga del Norte. NCP will provide program materials and technical assistance. Modeling activities will include advocating to local government units; designing and installing nutrition planning capability via planning workshops; packaging of program requirements and costs; designing a strategy to mobilize resources; facilitating purchase, delivery, and payment of program requirements; facilitating and coordinating training; designing and installing a monitoring and evaluation system; and documenting and disseminating. Local government officials, technical government agencies, nongovernment organizations, and private entities will work together. PMID:12287618

  11. Case Study: del Amo Bioventing

    EPA Science Inventory

    The attached presentation discusses the fundamentals of bioventing in the vadose zone. The basics of bioventing are presented. The experience to date with the del Amo Superfund Site is presented as a case study.

  12. The novel complex allele [A238V;F508del] of the CFTR gene: clinical phenotype and possible implications for cystic fibrosis etiological therapies.

    PubMed

    Diana, Anna; Polizzi, Angela Maria; Santostasi, Teresa; Ratclif, Luigi; Pantaleo, Maria Giuseppina; Leonetti, Giuseppina; Iusco, Danila Rosa; Gallo, Crescenzio; Conese, Massimo; Manca, Antonio

    2016-06-01

    Few mutations in cis have been annotated for F508del homozygous patients. Southern Italy patients who at a first analysis appeared homozygous for the F508del mutation (n=63) or compound heterozygous for the F508del and another mutation in the cystic fibrosis transmembrane conductance regulator gene (n=155) were searched for the A238V mutation in exon 6. The allelic frequency of the complex allele [A238V;F508del] was 0.04. When the whole data set was used (comprised also of 56 F508del/F508del and 34 F508del/other mutation controls), no differences reached the statistical significance in the clinical parameters, except chloride concentrations which were lower in [A238V;F508del]/other mutation compared with F508del/other mutation (P=0.03). The two study groups presented less complications than the control groups. Within the minimal data set (34 F508del/F508del, 27 F508del/other mutation, 4 [A238V;F508del]/F508del cases and 5 [A238V;F508del]/other mutation cases); that is, presenting all the variables in each patient, forced expiratory volume in 1 s and forced vital capacity presented a trend to lower levels in the study groups in comparison with the F508del/F508del group, and C-reactive protein approximated statistically significant higher levels in the [A238V;F508del]/other mutation as compared with F508del/F508del patients (P=0.09). The analysis of statistical dependence among the variables showed a significant anticorrelation between chloride and body mass index in the [A238V;F508del]/other mutation group. In conclusion, the complex allele [A238V;F508del] seems to be associated with less general complications than in the control groups, on the other hand possibly giving a worse pulmonary phenotype and higher systemic/local inflammatory response. These findings have implications for the correct recruitment and clinical response of F508del patients in the clinical trials testing the new etiological drugs for cystic fibrosis. PMID:26911355

  13. Our Local Superbubble and Local Bubble Environments

    NASA Astrophysics Data System (ADS)

    Heiles, Carl

    2009-08-01

    We briefly describe the local superbubbles and supershells that lie near the Sun. These include, of course, the famous ones-the Orion/Eridanus superbubble and the North Polar Spur shell. It also includes less famous, less prominent, older, but equally important ones: we stress the elliptical Lindblad Ring, which surrounds the Sun and has a maximum diameter 364 pc, and GSH 238+00+09, which is a huge old shell. Both appear to be responsible for shock-induced star formation; GSR 238+0+09, in particular, may be responsible for the Orion and Gum associations. We then turn to the Local Bubble and describe some of its little-known and remarkable occupants: interstellar scattering centers, which are ionized blobs having sizes of a few Earth diameters, and one of the coldest HI clouds known, which produces prominent X-ray shadow and allows us to estimate the local X-ray production rate within a few dozen parsec from the Sun.

  14. Localization of magnetic pills

    PubMed Central

    Laulicht, Bryan; Gidmark, Nicholas J.; Tripathi, Anubhav; Mathiowitz, Edith

    2011-01-01

    Numerous therapeutics demonstrate optimal absorption or activity at specific sites in the gastrointestinal (GI) tract. Yet, safe, effective pill retention within a desired region of the GI remains an elusive goal. We report a safe, effective method for localizing magnetic pills. To ensure safety and efficacy, we monitor and regulate attractive forces between a magnetic pill and an external magnet, while visualizing internal dose motion in real time using biplanar videofluoroscopy. Real-time monitoring yields direct visual confirmation of localization completely noninvasively, providing a platform for investigating the therapeutic benefits imparted by localized oral delivery of new and existing drugs. Additionally, we report the in vitro measurements and calculations that enabled prediction of successful magnetic localization in the rat small intestines for 12 h. The designed system for predicting and achieving successful magnetic localization can readily be applied to any area of the GI tract within any species, including humans. The described system represents a significant step forward in the ability to localize magnetic pills safely and effectively anywhere within the GI tract. What our magnetic pill localization strategy adds to the state of the art, if used as an oral drug delivery system, is the ability to monitor the force exerted by the pill on the tissue and to locate the magnetic pill within the test subject all in real time. This advance ensures both safety and efficacy of magnetic localization during the potential oral administration of any magnetic pill-based delivery system. PMID:21257903

  15. Local Power: Tribe & Township.

    ERIC Educational Resources Information Center

    Matlala, Padi; Moloi, Dudley

    1995-01-01

    Examines the service infrastructure of a rural township in South Africa and the struggle to acquire services like water and electricity. Discusses the interaction of a system of transitional local councils and tribal authorities in the face of local government elections. (LZ)

  16. Local available quantum correlations

    NASA Astrophysics Data System (ADS)

    Mundarain, Douglas F.; de Guevara, María L. Ladrón

    2015-12-01

    In this work, local available quantum correlations are studied. They are defined in terms of mutual information of bipartite local measurements done over an optimal local basis complementary to the local basis which defines the respective classical correlations. For two qubits, it is always possible to choose the basis of classical correlations as the set of eigenvectors of σ _z (the third Pauli matrix) and complementary bases become the sets of eigenvectors of the observables orthogonal to σ _z. It is shown that all states with zero local available quantum correlations are separable but not necessarily strictly classical; this fact puts this kind of correlations in the middle between discord and entanglement. Since in many cases it may suffice to know whether a given state has quantum correlations, the structure of the states with zero local available quantum correlations is presented. It is also shown that there is a close connection between local available quantum correlations and the protocol of entanglement activation developed by Piani et al. (Phys Rev Lett 106:220403, 2011). If a state satisfies the sufficient condition for the entanglement swapping associated with this protocol, this state has nonzero local available quantum correlations.

  17. Mechanisms Regulating Protein Localization.

    PubMed

    Bauer, Nicholas C; Doetsch, Paul W; Corbett, Anita H

    2015-10-01

    Cellular functions are dictated by protein content and activity. There are numerous strategies to regulate proteins varying from modulating gene expression to post-translational modifications. One commonly used mode of regulation in eukaryotes is targeted localization. By specifically redirecting the localization of a pool of existing protein, cells can achieve rapid changes in local protein function. Eukaryotic cells have evolved elegant targeting pathways to direct proteins to the appropriate cellular location or locations. Here, we provide a general overview of these localization pathways, with a focus on nuclear and mitochondrial transport, and present a survey of the evolutionarily conserved regulatory strategies identified thus far. We end with a description of several specific examples of proteins that exploit localization as an important mode of regulation. PMID:26172624

  18. Local likelihood estimation

    SciTech Connect

    Tibshirani, R.J.

    1984-12-01

    In this work, we extend the idea of local averaging to likelihood-based regression models. One application is in the class of generalized linear models (Nelder and Wedderburn (1972). We enlarge this class by replacing the covariate form chi..beta.. with an unspecified smooth function s(chi). This function is estimated from the data by a technique we call Local Likelihood Estimation - a type of local averaging. Multiple covariates are incorporated through a forward stepwise algorithm. In a number of real data examples, the local likelihood technique proves to be effective in uncovering non-linear dependencies. Finally, we give some asymptotic results for local likelihood estimates and provide some methods for inference.

  19. Localization by entanglement

    NASA Astrophysics Data System (ADS)

    Brand, J.; Flach, S.; Fleurov, V.; Schulman, L. S.; Tolkunov, D.

    2008-08-01

    We study the localization of bosonic atoms in an optical lattice, which interact in a spatially confined region. The classical theory predicts that there is no localization below a threshold value for the strength of interaction that is inversely proportional to the number of participating atoms. In a full quantum treatment, however, we find that localized states exist for arbitrarily weak attractive or repulsive interactions for any number (>1) of atoms. We further show, using an explicit solution of the two-particle bound state and an appropriate measure of entanglement, that the entanglement tends to a finite value in the limit of weak interactions. Coupled with the non-existence of localization in an optimized quantum product state, we conclude that the localization exists by virtue of entanglement.

  20. DEL-1 restrains osteoclastogenesis and inhibits inflammatory bone loss in nonhuman primates.

    PubMed

    Shin, Jieun; Maekawa, Tomoki; Abe, Toshiharu; Hajishengallis, Evlambia; Hosur, Kavita; Pyaram, Kalyani; Mitroulis, Ioannis; Chavakis, Triantafyllos; Hajishengallis, George

    2015-09-30

    DEL-1 (developmental endothelial locus-1) is an endothelial cell-secreted protein that regulates LFA-1 (lymphocyte function-associated antigen-1) integrin-dependent leukocyte recruitment and inflammation in various tissues. We identified a novel regulatory mechanism of DEL-1 in osteoclast biology. Specifically, we showed that DEL-1 is expressed by human and mouse osteoclasts and regulates their differentiation and resorptive function. Mechanistically, DEL-1 inhibited the expression of NFATc1, a master regulator of osteoclastogenesis, in a Mac-1 integrin-dependent manner. In vivo mechanistic analysis has dissociated the anti-inflammatory from the anti-bone-resorptive action of DEL-1 and identified structural components thereof mediating these distinct functions. Locally administered human DEL-1 blocked inflammatory periodontal bone loss in nonhuman primates-a relevant model of human periodontitis. The ability of DEL-1 to regulate both upstream (inflammatory cell recruitment) and downstream (osteoclastogenesis) events that lead to inflammatory bone loss paves the way to a new class of endogenous therapeutics for treating periodontitis and perhaps other inflammatory disorders. PMID:26424570

  1. Stereotype locally convex spaces

    NASA Astrophysics Data System (ADS)

    Akbarov, S. S.

    2000-08-01

    We give complete proofs of some previously announced results in the theory of stereotype (that is, reflexive in the sense of Pontryagin duality) locally convex spaces. These spaces have important applications in topological algebra and functional analysis.

  2. Ergodicity breaking and localization.

    PubMed

    Geneston, Elvis; Tuladhar, Rohisha; Beig, M T; Bologna, Mauro; Grigolini, Paolo

    2016-07-01

    We study the joint action of the non-Poisson renewal events (NPR) yielding Continuous-time random walk (CTRW) with index α<1 and two different generators of Hurst coefficient H≠0.5, one generating fractional Brownian motion (FBM) and another scaled Brownian motion (SBM). We discuss the ergodicity breaking emerging from these joint actions and we find that in both cases the adoption of time averages leads to localization. In the case of the joint action of NPR and SBM, localization occurs when SBM would produce subdiffusion. The joint action of NPR and FBM, on the contrary, may lead to localization when FBM is a source of superdiffusion. The joint action of NPR and FBM is equivalent to extending the CTRW to the case where the jumps of the runner are correlated and we argue that the the memory-induced localization requires a refinement of the theoretical perspective about determinism and randomness. PMID:27575105

  3. Focus on Local Reaction.

    ERIC Educational Resources Information Center

    Howe, Rod

    1999-01-01

    Discusses how the student newspaper "The Lance" (at Westside High School in Omaha, Nebraska) covered the shootings at Columbine High School. Notes that the staff localized the event and brought the student body into the story. (RS)

  4. Ergodicity breaking and localization

    NASA Astrophysics Data System (ADS)

    Geneston, Elvis; Tuladhar, Rohisha; Beig, M. T.; Bologna, Mauro; Grigolini, Paolo

    2016-07-01

    We study the joint action of the non-Poisson renewal events (NPR) yielding Continuous-time random walk (CTRW) with index α <1 and two different generators of Hurst coefficient H ≠0.5 , one generating fractional Brownian motion (FBM) and another scaled Brownian motion (SBM). We discuss the ergodicity breaking emerging from these joint actions and we find that in both cases the adoption of time averages leads to localization. In the case of the joint action of NPR and SBM, localization occurs when SBM would produce subdiffusion. The joint action of NPR and FBM, on the contrary, may lead to localization when FBM is a source of superdiffusion. The joint action of NPR and FBM is equivalent to extending the CTRW to the case where the jumps of the runner are correlated and we argue that the the memory-induced localization requires a refinement of the theoretical perspective about determinism and randomness.

  5. Local entropy generation analysis

    SciTech Connect

    Drost, M.K.; White, M.D.

    1991-02-01

    Second law analysis techniques have been widely used to evaluate the sources of irreversibility in components and systems of components but the evaluation of local sources of irreversibility in thermal processes has received little attention. While analytical procedures for evaluating local entropy generation have been developed, applications have been limited to fluid flows with analytical solutions for the velocity and temperature fields. The analysis of local entropy generation can be used to evaluate more complicated flows by including entropy generation calculations in a computational fluid dynamics (CFD) code. The research documented in this report consists of incorporating local entropy generation calculations in an existing CFD code and then using the code to evaluate the distribution of thermodynamic losses in two applications: an impinging jet and a magnetic heat pump. 22 refs., 13 figs., 9 tabs.

  6. Anderson Localization of Solitons

    NASA Astrophysics Data System (ADS)

    Sacha, Krzysztof; Müller, Cord A.; Delande, Dominique; Zakrzewski, Jakub

    2009-11-01

    At low temperature, a quasi-one-dimensional ensemble of atoms with an attractive interaction forms a bright soliton. When exposed to a weak and smooth external potential, the shape of the soliton is hardly modified, but its center-of-mass motion is affected. We show that in a spatially correlated disordered potential, the quantum motion of a bright soliton displays Anderson localization. The localization length can be much larger than the soliton size and could be observed experimentally.

  7. Localized pityriasis rosea.

    PubMed

    Ahmed, I; Charles-Holmes, R

    2000-11-01

    Pityriasis rosea is a relatively common skin disorder. In its typical form it is easily recognizable; however, atypical forms can pose diagnostic problems. We report a 44-year-old woman with an acute onset of a localized eruption on her left breast. The morphology of the rash and the time course were typical of pityriasis rosea. Localized pityriasis rosea is an unusual variant, which has been described previously. PMID:11167977

  8. Anderson Localization of Solitons

    SciTech Connect

    Sacha, Krzysztof; Zakrzewski, Jakub; Mueller, Cord A.; Delande, Dominique

    2009-11-20

    At low temperature, a quasi-one-dimensional ensemble of atoms with an attractive interaction forms a bright soliton. When exposed to a weak and smooth external potential, the shape of the soliton is hardly modified, but its center-of-mass motion is affected. We show that in a spatially correlated disordered potential, the quantum motion of a bright soliton displays Anderson localization. The localization length can be much larger than the soliton size and could be observed experimentally.

  9. Localization protected quantum order

    NASA Astrophysics Data System (ADS)

    Nandkishore, Rahul

    2015-03-01

    Many body localization occurs in isolated quantum systems, usually with strong disorder, and is marked by absence of dissipation, absence of thermal equilibration, and a memory of the initial conditions that survives in local observables for arbitrarily long times. The many body localized regime is a non-equilibrium, strongly disordered, non-self averaging regime that presents a new frontier for quantum statistical mechanics. In this talk, I point out that there exists a vast zoo of correlated many body localized states of matter, which may be classified using familiar notions of spontaneous symmetry breaking and topological order. I will point out that in the many body localized regime, spontaneous symmetry breaking can occur even at high energy densities in one dimensional systems, and topological order can occur even without a bulk gap. I will also discuss the phenomenology of imperfectly isolated many body localized systems, which are weakly coupled to a heat bath. I will conclude with a brief discussion of how these phenomena may best be detected in experiments. Collaborators: David Huse, S.L. Sondhi, Arijeet Pal, Vadim Oganesyan, A.C. Potter, Sarang Gopalakrishnan, S. Johri, R.N. Bhatt.

  10. Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression

    PubMed Central

    Adkisson, Michael; Nava, A. J.; Kirov, Julia V.; Cipollone, Andreanna; Willis, Brandon; Rapp, Jared; de Jong, Pieter J.; Lloyd, Kent C.

    2016-01-01

    The unintended consequences of gene targeting in mouse models have not been thoroughly studied and a more systematic analysis is needed to understand the frequency and characteristics of off-target effects. Using RNA-seq, we evaluated targeted and neighboring gene expression in tissues from 44 homozygous mutants compared with C57BL/6N control mice. Two allele types were evaluated: 15 targeted trap mutations (TRAP); and 29 deletion alleles (DEL), usually a deletion between the translational start and the 3’ UTR. Both targeting strategies insert a bacterial beta-galactosidase reporter (LacZ) and a neomycin resistance selection cassette. Evaluating transcription of genes in +/- 500 kb of flanking DNA around the targeted gene, we found up-regulated genes more frequently around DEL compared with TRAP alleles, however the frequency of alleles with local down-regulated genes flanking DEL and TRAP targets was similar. Down-regulated genes around both DEL and TRAP targets were found at a higher frequency than expected from a genome-wide survey. However, only around DEL targets were up-regulated genes found with a significantly higher frequency compared with genome-wide sampling. Transcriptome analysis confirms targeting in 97% of DEL alleles, but in only 47% of TRAP alleles probably due to non-functional splice variants, and some splicing around the gene trap. Local effects on gene expression are likely due to a number of factors including compensatory regulation, loss or disruption of intragenic regulatory elements, the exogenous promoter in the neo selection cassette, removal of insulating DNA in the DEL mutants, and local silencing due to disruption of normal chromatin organization or presence of exogenous DNA. An understanding of local position effects is important for understanding and interpreting any phenotype attributed to targeted gene mutations, or to spontaneous indels. PMID:26839965

  11. LOCAL TADPOLE GALAXIES

    SciTech Connect

    Elmegreen, Debra Meloy; Putko, Joseph; Dewberry, Janosz; Elmegreen, Bruce G.; Sanchez Almeida, Jorge; Munoz-Tunon, Casiana

    2012-05-10

    Tadpole galaxies have a giant star-forming region at the end of an elongated intensity distribution. Here we use Sloan Digital Sky Survey data to determine the ages, masses, and surface densities of the heads and tails in 14 local tadpoles selected from the Kiso and Michigan surveys of UV-bright galaxies, and we compare them to tadpoles previously studied in the Hubble Ultra Deep Field. The young stellar mass in the head scales linearly with rest-frame galaxy luminosity, ranging from {approx}10{sup 5} M{sub Sun} at galaxy absolute magnitude U = -13 mag to 10{sup 9} M{sub Sun} at U = -20 mag. The corresponding head surface density increases from several M {sub Sun} pc{sup -2} locally to 10-100 M{sub Sun} pc{sup -2} at high redshift, and the star formation rate (SFR) per unit area in the head increases from {approx}0.01 M{sub Sun} yr{sup -1} kpc{sup -2} locally to {approx}1 M{sub Sun} yr{sup -1} kpc{sup -2} at high z. These local values are normal for star-forming regions, and the increases with redshift are consistent with other cosmological SFRs, most likely reflecting an increase in gas abundance. The tails in the local sample look like bulge-free galaxy disks. Their photometric ages decrease from several Gyr to several hundred Myr with increasing z, and their surface densities are more constant than the surface densities of the heads. The far-outer intensity profiles in the local sample are symmetric and exponential. We suggest that most local tadpoles are bulge-free galaxy disks with lopsided star formation, perhaps from environmental effects such as ram pressure or disk impacts, or from a Jeans length comparable to half the disk size.

  12. Monaural Sound Localization Revisited

    NASA Technical Reports Server (NTRS)

    Wightman, Frederic L.; Kistler, Doris J.

    1997-01-01

    Research reported during the past few decades has revealed the importance for human sound localization of the so-called 'monaural spectral cues.' These cues are the result of the direction-dependent filtering of incoming sound waves accomplished by the pinnae. One point of view about how these cues are extracted places great emphasis on the spectrum of the received sound at each ear individually. This leads to the suggestion that an effective way of studying the influence of these cues is to measure the ability of listeners to localize sounds when one of their ears is plugged. Numerous studies have appeared using this monaural localization paradigm. Three experiments are described here which are intended to clarify the results of the previous monaural localization studies and provide new data on how monaural spectral cues might be processed. Virtual sound sources are used in the experiments in order to manipulate and control the stimuli independently at the two ears. Two of the experiments deal with the consequences of the incomplete monauralization that may have contaminated previous work. The results suggest that even very low sound levels in the occluded ear provide access to interaural localization cues. The presence of these cues complicates the interpretation of the results of nominally monaural localization studies. The third experiment concerns the role of prior knowledge of the source spectrum, which is required if monaural cues are to be useful. The results of this last experiment demonstrate that extraction of monaural spectral cues can be severely disrupted by trial-to-trial fluctuations in the source spectrum. The general conclusion of the experiments is that, while monaural spectral cues are important, the monaural localization paradigm may not be the most appropriate way to study their role.

  13. Local relativistic exact decoupling.

    PubMed

    Peng, Daoling; Reiher, Markus

    2012-06-28

    We present a systematic hierarchy of approximations for local exact decoupling of four-component quantum chemical Hamiltonians based on the Dirac equation. Our ansatz reaches beyond the trivial local approximation that is based on a unitary transformation of only the atomic block-diagonal part of the Hamiltonian. Systematically, off-diagonal Hamiltonian matrix blocks can be subjected to a unitary transformation to yield relativistically corrected matrix elements. The full hierarchy is investigated with respect to the accuracy reached for the electronic energy and for selected molecular properties on a balanced test molecule set that comprises molecules with heavy elements in different bonding situations. Our atomic (local) assembly of the unitary exact-decoupling transformation--called local approximation to the unitary decoupling transformation (DLU)--provides an excellent local approximation for any relativistic exact-decoupling approach. Its order-N(2) scaling can be further reduced to linear scaling by employing a neighboring-atomic-blocks approximation. Therefore, DLU is an efficient relativistic method well suited for relativistic calculations on large molecules. If a large molecule contains many light atoms (typically hydrogen atoms), the computational costs can be further reduced by employing a well-defined nonrelativistic approximation for these light atoms without significant loss of accuracy. We also demonstrate that the standard and straightforward transformation of only the atomic block-diagonal entries in the Hamiltonian--denoted diagonal local approximation to the Hamiltonian (DLH) in this paper--introduces an error that is on the order of the error of second-order Douglas-Kroll-Hess (i.e., DKH2) when compared with exact-decoupling results. Hence, the local DLH approximation would be pointless in an exact-decoupling framework, but can be efficiently employed in combination with the fast to evaluate DKH2 Hamiltonian in order to speed up calculations

  14. Vacunas contra los virus del papiloma humano

    Cancer.gov

    Una hoja informativa acerca de las vacunas contra los virus del papiloma humano (VPH) para prevenir infecciones con ciertos tipos de VPH, los cuales son la causa principal del cáncer de cuello del útero o cérvix.

  15. Lauding Local Legacies.

    ERIC Educational Resources Information Center

    Lamolinara, Guy

    1999-01-01

    As part of its bicentennial celebration, the Library of Congress is sponsoring the Local Legacies project, an unprecedented effort in which Americans across the nation work with their members of Congress to document unique traditions for the collections of the American Folklife Center. Libraries will have a critical role in directing documentation…

  16. Theme: Local Program Success.

    ERIC Educational Resources Information Center

    Camp, William G.; And Others

    1997-01-01

    Includes "Professional Propagation" (Camp); "Managing Human Resources with Local Program Success (LPS)" (Daley); "Profit Sharing with LPS" (Moses); "Partners for Success" (Mecey- Smith); "Achieving LPS by Collaborating with Partners, Allies and Volunteers" (Oglesby); LPS...Just What Agricultural Education Needs, Another Acronym" (Rist); "The…

  17. Local Area Networks.

    ERIC Educational Resources Information Center

    Nasatir, Marilyn; And Others

    1990-01-01

    Four papers discuss LANs (local area networks) and library applications: (1) "Institute for Electrical and Electronic Engineers Standards..." (Charles D. Brown); (2) "Facilities Planning for LANs..." (Gail Persky); (3) "Growing up with the Alumni Library: LAN..." (Russell Buchanan); and (4) "Implementing a LAN...at the Health Sciences Library"…

  18. Local Area Networks.

    ERIC Educational Resources Information Center

    Bullard, David

    1983-01-01

    The proliferation of word processors, micro- and minicomputer systems, and other digital office equipment is causing major design changes in existing networks. Local Area Networks (LANs) which have adequately served terminal users in the past must now be redesigned. Implementation at Clemson is described. (MLW)

  19. Local Area Networks.

    ERIC Educational Resources Information Center

    Marks, Kenneth E.; Nielsen, Steven

    1991-01-01

    Discusses cabling that is needed in local area networks (LANs). Types of cables that may be selected are described, including twisted pair, coaxial cables (or ethernet), and fiber optics; network topologies, the manner in which the cables are laid out, are considered; and cable installation issues are discussed. (LRW)

  20. Social Studies: Local History.

    ERIC Educational Resources Information Center

    Kressler, Joe, Comp.

    Elementary and secondary school teachers interested in developing a local history unit can adapt this fourth grade program created for three school districts in Cortland County, New York. Material is divided into 13 chapters. Chapter 1 charts the New York fourth grade curriculum by concept and content and outlines specific community study…

  1. Tackling a Local Problem.

    ERIC Educational Resources Information Center

    Cook, Martin

    1995-01-01

    Students studying water as a class project were concerned by levels of pollution at a nearby river and the local beach. They identified three environmental problems for research including sewage discharge, beach litter, and quality of swimming water. Research consisted of field trips which allowed for opportunities to improve skills in collecting…

  2. State and local governments

    NASA Technical Reports Server (NTRS)

    Barnes, Dennis

    1990-01-01

    The Virginia Space Grant Consortium approach to a close working relation to state and local governments is presented as a model for consideration. State government relations are especially important in that this is a primary resource in securing matching funds. Avenues for establishing these relationships are listed and discussed.

  3. Teaching Local History.

    ERIC Educational Resources Information Center

    Singer, Alan, Ed.

    2003-01-01

    This Social Science Docket theme issue focuses on teaching local history and included theme and non-themed articles, lesson plans, learning activities, and book, movie, and museum reviews designed for K-12 social studies teachers. Articles and materials in this issue are: "Editing Is Not Censorship" (Alan Singer); "Teachers Respond to 'Editing Is…

  4. Symbolic local information transfer

    NASA Astrophysics Data System (ADS)

    Nakajima, K.; Haruna, T.

    2013-06-01

    Recently, the permutation-information theoretic approach has been used in a broad range of research fields. In particular, in the study of high-dimensional dynamical systems, it has been shown that this approach can be effective in characterizing global properties, including the complexity of their spatiotemporal dynamics. Here, we show that this approach can also be applied to reveal local spatiotemporal profiles of distributed computations existing at each spatiotemporal point in the system. J. T. Lizier et al. have recently introduced the concept of local information dynamics, which consists of information storage, transfer, and modification. This concept has been intensively studied with regard to cellular automata, and has provided quantitative evidence of several characteristic behaviors observed in the system. In this paper, by focusing on the local information transfer, we demonstrate that the application of the permutation-information theoretic approach, which introduces natural symbolization methods, makes the concept easily extendible to systems that have continuous states. We propose measures called symbolic local transfer entropies, and apply these measures to two test models, the coupled map lattice (CML) system and the Bak-Sneppen model (BS-model), to show their relevance to spatiotemporal systems that have continuous states. In the CML, we demonstrate that it can be successfully used as a spatiotemporal filter to stress a coherent structure buried in the system. In particular, we show that the approach can clearly stress out defect turbulences or Brownian motion of defects from the background, which gives quantitative evidence suggesting that these moving patterns are the information transfer substrate in the spatiotemporal system. We then show that these measures reveal qualitatively different properties from the conventional approach using the sliding window method, and are also robust against external noise. In the BS-model, we demonstrate that

  5. Medical ethnobotany of the Teribes of Bocas del Toro, Panama.

    PubMed

    Gupta, M P; Solís, P N; Calderón, A I; Guionneau-Sinclair, F; Guinneau-Sinclair, F; Correa, M; Galdames, C; Guerra, C; Espinosa, A; Alvenda, G I; Robles, G; Ocampo, R

    2005-01-15

    Ethnomedical uses of 108 medicinal plant species, belonging to 52 families, 89 genera, used by the Teribe Amerindians of Bocas del Toro Province in Panama, along with their socio-cultural practices are reported here. The methods of administration of the herbal remedies, the plant parts used, their families and local names are also documented. The recorded medicinal plants were used mainly for fever, various type of pain and inflammation. The potential value of 26 plants and their traditional uses was elucidated through literature search. PMID:15619557

  6. Localization and vector spherical harmonics

    NASA Astrophysics Data System (ADS)

    von Brecht, James H.

    2016-01-01

    This paper establishes the following localization property for vector spherical harmonics: a wide class of non-local, vector-valued operators reduce to local, multiplication-type operations when applied to a vector spherical harmonic. As localization occurs in a very precise, quantifiable and explicitly computable fashion, the localization property provides a set of useful formulae for analyzing vector-valued fractional diffusion and non-local differential equations defined on S d - 1. As such analyses require a detailed understanding of operators for which localization occurs, we provide several applications of the result in the context of non-local differential equations.

  7. Local normal galaxies

    NASA Technical Reports Server (NTRS)

    Fichtel, Carl E.

    1990-01-01

    In the near future, high energy (E greater than 20 MeV) gamma ray astronomy offers the promise of a new means of examining the closest galaxies. Two and possibly three local galaxies, the Small and Large Magellanic Clouds and M31, should be visible to the high energy gamma ray telescope on the Gamma Ray Observatory, and the first should be seen by GAMMA-1. With the assumptions of adequate cosmic ray production and reasonable magnetic field strengths, both of which should likely be satisfied, specific predictions of the gamma ray emission can be made separating the concepts of the galactic and universal nature of cosmic rays. A study of the synchrotron radiation from the Large Magellanic Cloud (LMC) suggests that the cosmic ray density is similar to that in the local region of our galaxy, but not uniform. It is hoped the measurements will be able to verify this independent of assumptions about the magnetic fields in the LMC.

  8. Stable local oscillator module.

    SciTech Connect

    Brocato, Robert Wesley

    2007-11-01

    This report gives a description of the development of a Stable Local Oscillator (StaLO) multi-chip module (MCM). It is a follow-on report to SAND2006-6414, Stable Local Oscillator Microcircuit. The StaLO accepts a 100MHz input signal and produces output signals at 1.2, 3.3, and 3.6 GHz. The circuit is built as a multi-chip module (MCM), since it makes use of integrated circuit technologies in silicon and lithium niobate as well as discrete passive components. This report describes the development of an MCM-based version of the complete StaLO, fabricated on an alumina thick film hybrid substrate.

  9. Broadband local dielectric spectroscopy

    NASA Astrophysics Data System (ADS)

    Labardi, M.; Lucchesi, M.; Prevosto, D.; Capaccioli, S.

    2016-05-01

    A route to extend the measurement bandwidth of local dielectric spectroscopy up to the MHz range has been devised. The method is based on a slow amplitude modulation at a frequency Ω of the excitation field oscillating at a frequency ω and the coherent detection of the modulated average electric force or force gradient at Ω. The cantilever mechanical response does not affect the measurement if Ω is well below its resonant frequency; therefore, limitations on the excitation field frequency are strongly reduced. Demonstration on a thin poly(vinyl acetate) film is provided, showing its structural relaxation spectrum on the local scale up to 45 °C higher than glass temperature, and nanoscale resolution dielectric relaxation imaging near conductive nanowires embedded in the polymer matrix was obtained up to 5 MHz frequency, with no physical reason to hinder further bandwidth extension.

  10. Local quantum gravity

    NASA Astrophysics Data System (ADS)

    Christiansen, N.; Knorr, B.; Meibohm, J.; Pawlowski, J. M.; Reichert, M.

    2015-12-01

    We investigate the ultraviolet behavior of quantum gravity within a functional renormalization group approach. The present setup includes the full ghost and graviton propagators and, for the first time, the dynamical graviton three-point function. The latter gives access to the coupling of dynamical gravitons and makes the system minimally self-consistent. The resulting phase diagram confirms the asymptotic safety scenario in quantum gravity with a nontrivial UV fixed point. A well-defined Wilsonian block spinning requires locality of the flow in momentum space. This property is discussed in the context of functional renormalization group flows. We show that momentum locality of graviton correlation functions is nontrivially linked to diffeomorphism invariance, and is realized in the present setup.

  11. Classical dynamical localization.

    PubMed

    Guarneri, Italo; Casati, Giulio; Karle, Volker

    2014-10-24

    We consider classical models of the kicked rotor type, with piecewise linear kicking potentials designed so that momentum changes only by multiples of a given constant. Their dynamics display quasilocalization of momentum, or quadratic growth of energy, depending on the arithmetic nature of the constant. Such purely classical features mimic paradigmatic features of the quantum kicked rotor, notably dynamical localization in momentum, or quantum resonances. We present a heuristic explanation, based on a classical phase space generalization of a well-known argument, that maps the quantum kicked rotor on a tight-binding model with disorder. Such results suggest reconsideration of generally accepted views that dynamical localization and quantum resonances are a pure result of quantum coherence. PMID:25379918

  12. The Local Dark Matter

    SciTech Connect

    Helfer, H.L.

    2005-10-21

    The observations of the extended rotation curves of some galaxies provide important constraints upon the nature of the local dark matter present in the halos of these galaxies. Using these constraints, one can show that the halo dark matter cannot be some population of conventional astronomical objects and (most probably) cannot be a population of exotic non-interacting particles. We suggest that the halos can be regarded as large spatial fluctuations in a classic scalar field.

  13. [Cardiotoxicity of local anesthetics].

    PubMed

    de La Coussaye, J E; Eledjam, J J; Brugada, J; Sassine, A

    1993-01-01

    The intravascular administration and the high blood resorption of local anesthetic agents are known to induce neurotoxic accidents. However, the use of potent local anesthetic drugs such as bupivacaine is responsible for serious cardiotoxic accidents with a mortality of about 50%. Indeed, bupivacaine induces both electrophysiologic and haemodynamic disturbances with the occurrence of conduction blocks, arrhythmias and cardiovascular collapse. Moreover, cardiotoxicity is worsened by: bupivacaine-induced sympathetic activation which facilitates tachycardia and arrhythmias, metabolic abnormalities such as hypoxia, acidosis, hyperkaliemia and hypothermia, pregnancy, diazepam pretreatment, and the antiarrhythmic drugs. In case of cardiac arrest, CPR must be made. In the other cases, the first treatment is to oxygenate, to intubate the trachea and to ventilate the lungs, and then to stop convulsions. Specific cardiac resuscitation remains controversial because it is based principally on experimental results. We demonstrated that the combination of clonidine and dobutamine is efficient to reverse both haemodynamic and electrophysiologic impairments induced by a large dose of bupivacaine in anesthetized dogs. Whatever the efficiency of specific resuscitation, it must be emphasized that prevention of toxic accident must always include: the best choice of local anesthetic drug (e.g.: lidocaine+alpha-2 agonist vs bupivacaine), test dose, aspiration and slow administration. Finally, the monitoring of regional anaesthesia must be similar to that in use for general anaesthesia and drugs and devices for resuscitation must be ready. PMID:8287299

  14. Acoustic source localization.

    PubMed

    Kundu, Tribikram

    2014-01-01

    In this article different techniques for localizing acoustic sources are described and the advantages/disadvantages of these techniques are discussed. Some source localization techniques are restricted to isotropic structures while other methods can be applied to anisotropic structures as well. Some techniques require precise knowledge of the direction dependent velocity profiles in the anisotropic body while other techniques do not require that knowledge. Some methods require accurate values of the time of arrival of the acoustic waves at the receivers while other techniques can function without that information. Published papers introducing various techniques emphasize the advantages of the introduced techniques while ignoring and often not mentioning the limitations and weaknesses of the new techniques. What is lacking in the literature is a comprehensive review and comparison of the available techniques; this article attempts to do that. After reviewing various techniques the paper concludes which source localization technique should be most effective for what type of structure and what the current research needs are. PMID:23870388

  15. Enhanced local tomography

    DOEpatents

    Katsevich, Alexander J.; Ramm, Alexander G.

    1996-01-01

    Local tomography is enhanced to determine the location and value of a discontinuity between a first internal density of an object and a second density of a region within the object. A beam of radiation is directed in a predetermined pattern through the region of the object containing the discontinuity. Relative attenuation data of the beam is determined within the predetermined pattern having a first data component that includes attenuation data through the region. In a first method for evaluating the value of the discontinuity, the relative attenuation data is inputted to a local tomography function .function..sub..LAMBDA. to define the location S of the density discontinuity. The asymptotic behavior of .function..sub..LAMBDA. is determined in a neighborhood of S, and the value for the discontinuity is estimated from the asymptotic behavior of .function..sub..LAMBDA.. In a second method for evaluating the value of the discontinuity, a gradient value for a mollified local tomography function .gradient..function..sub..LAMBDA..epsilon. (x.sub.ij) is determined along the discontinuity; and the value of the jump of the density across the discontinuity curve (or surface) S is estimated from the gradient values.

  16. Local Affinity Release.

    PubMed

    Delplace, Vianney; Obermeyer, Jaclyn; Shoichet, Molly S

    2016-07-26

    The use of hydrogels for therapeutic delivery is a burgeoning area of investigation. These water-swollen polymer matrices are ideal platforms for localized drug delivery that can be further combined with specific ligands or nanotechnologies to advance the controlled release of small-molecule drugs and proteins. Due to the advantage of hydrophobic, electrostatic, or specific extracellular matrix interactions, affinity-based strategies can overcome burst release and challenges associated with encapsulation. Future studies will provide innovative binding tools, truly stimuli-responsive systems, and original combinations of emerging technologies to control the release of therapeutics spatially and temporally. Local drug delivery can be achieved by directly injecting a therapeutic to its site of action and is advantageous because off-target effects associated with systemic delivery can be minimized. For prolonged benefit, a vehicle that provides sustained drug release is required. Hydrogels are versatile platforms for localized drug release, owing to the large library of biocompatible building blocks from which they can be formed. Injectable hydrogel formulations that gel quickly in situ and provide sustained release of therapeutics are particularly advantageous to minimize invasiveness. The incorporation of polymers, ligands or nanoparticles that have an affinity for the therapeutic of interest improve control over the release of small-molecule drugs and proteins from hydrogels, enabling spatial and temporal control over the delivery. Such affinity-based strategies can overcome drug burst release and challenges associated with protein instability, allowing more effective therapeutic molecule delivery for a range of applications from therapeutic contact lenses to ischemic tissue regeneration. PMID:27403513

  17. Localized acoustic surface modes

    NASA Astrophysics Data System (ADS)

    Farhat, Mohamed; Chen, Pai-Yen; Bağcı, Hakan

    2016-04-01

    We introduce the concept of localized acoustic surface modes. We demonstrate that they are induced on a two-dimensional cylindrical rigid surface with subwavelength corrugations under excitation by an incident acoustic plane wave. Our results show that the corrugated rigid surface is acoustically equivalent to a cylindrical scatterer with uniform mass density that can be represented using a Drude-like model. This, indeed, suggests that plasmonic-like acoustic materials can be engineered with potential applications in various areas including sensing, imaging, and cloaking.

  18. Local Allergic Rhinitis.

    PubMed

    Campo, Paloma; Salas, María; Blanca-López, Natalia; Rondón, Carmen

    2016-05-01

    This review focuses on local allergic rhinitis, a new phenotype of allergic rhinitis, commonly misdiagnosed as nonallergic rhinitis. It has gained attention over last decade and can affect patients from all countries, ethnic groups and ages, impairing their quality of life, and is frequently associated with conjunctivitis and asthma. Diagnosis is based on clinical history, the demonstration of a positive response to nasal allergen provocation test and/or the detection of nasal sIgE. A positive basophil activation test may support the diagnosis. Recent studies have demonstrated that allergen immunotherapy is an effective immune-modifying treatment, highlighting the importance of early diagnosis. PMID:27083105

  19. Local Group Cosmology

    NASA Astrophysics Data System (ADS)

    Martínez-Delgado, David

    2013-11-01

    List of contributors; List of participants; Preface; Acknowledgments; Abbreviations; 1. The formation of the Milky Way in the CDM paradigm Ken Freeman; 2. Dark matter content and tidal effects in Local Group dwarf galaxies Steven R. Majewski; 3. Notes on the missing satellites problem James Bullock; 4. The Milky Way satellite galaxies Pavel Kroupa; 5. Stellar tidal streams Rodrigo Ibata; 6. Tutorial: the analysis of colour-magnitude diagrams David Valls-Gabaud; 7. Tutorial: modeling tidal streams using N-body simulations Jorge Peñarrubia.

  20. Research fuels local economies

    SciTech Connect

    Bosisio, M. )

    1990-04-01

    Research from US DOA-Agricultural Research Service (ARS) has resulted in a number of new products, alternative crops, and an increase in planted acreage of crops due to pest control by pheromones. Superslurper, produced from cornstarch, was found to absorb 1400 times its weight in moisture. This material is being used in fuel filters to remove water in fuel tanks and pumps. There is a growing market for these filters; superslurpers also are used in body powders, diapers, absorbent soft goods, batteries, soil additives, and in medical and recreational coldpacks. Local economies have benefited as a direct result of ARS efforts.

  1. Tierra del Fuego, Argentina, South America

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The Mitre Peninsula is the easternmost tip of Tierra del Fuego, Argentina, (54.5S, 65.5W). Early winter snow can be seen on this south tip of the Andes Mountains. These same mountains continue underwater to Antarctica. The Strait of Magellan, separating the South American mainland from Tierra del Fuego is off the scene to the north and west, but the Strait of LeMaire, separating Tierra del Fuego from the Isla de los Estados can be seen.

  2. The Local Interstellar Medium

    NASA Astrophysics Data System (ADS)

    Redfield, S.

    2006-09-01

    The Local Interstellar Medium (LISM) is a unique environment that presents an opportunity to study general interstellar phenomena in great detail and in three dimensions. In particular, high resolution optical and ultraviolet spectroscopy have proven to be powerful tools for addressing fundamental questions concerning the physical conditions and three-dimensional (3D) morphology of this local material. After reviewing our current understanding of the structure of gas in the solar neighborhood, I will discuss the influence that the LISM can have on stellar and planetary systems, including LISM dust deposition onto planetary atmospheres and the modulation of galactic cosmic rays through the astrosphere --- the balancing interface between the outward pressure of the magnetized stellar wind and the inward pressure of the surrounding interstellar medium. On Earth, galactic cosmic rays may play a role as contributors to ozone layer chemistry, planetary electrical discharge frequency, biological mutation rates, and climate. Since the LISM shares the same volume as practically all known extrasolar planets, the prototypical debris disks systems, and nearby low-mass star-formation sites, it will be important to understand the structures of the LISM and how they may influence planetary atmospheres.

  3. Pattern Driven Stress Localization

    NASA Astrophysics Data System (ADS)

    Croll, Andrew; Crosby, Alfred

    2010-03-01

    The self-assembly of patterns from isotropic initial states is a major driver of modern soft-matter research. This avenue of study is directed by the desire to understand the complex physics of the varied structures found in Nature, and by technological interest in functional materials that may be derived through biomimicry. In this work we show how a simple striped phase can respond with significant complexity to an appropriately chosen perturbation. In particular, we show how a buckled elastic plate transitions into a state of stress localization using a simple, self-assembled variation in surface topography. The collection of topographic boundaries act in concert to change the state from isotropic sinusoidal wrinkles, to sharp folds or creases separated by relatively flat regions. By varying the size of the imposed topographic pattern or the wavelength of the wrinkles, we construct a state diagram of the system. The localized state has implications for both biological systems, and for the control of non-linear pattern formation.

  4. LOCALITY AND REALITY

    SciTech Connect

    Stapp, Henry P.

    1980-02-01

    Einstein's principle that no signal travels faster than suggests that observations in one spacetime region should not depend on whether or not a radioactive decay is detected in a spacelike separated region. This locality property is incompatible with the predictions of quantum theory, and this incompatibility holds independently of the questions of realism, objective reality, and hidden variables. It holds both in the pragmatic quantum theory of Bohr and in realistic frameworks. It is shown here to hold in a completed realistic quantum theory that reconciles Einstein's demand for a description of reality itself with Bohr's contention that quantum theory is complete. This completed realistic quantum theory has no hidden variables, and no objective reality in which observable attributes can become definite independently of observers. The, theory is described in some detail, with particular attention to those aspects related to the question of locality. This completed realistic quantum theory is in principle more comprehensive than Bohr.' s pragmatic quantum theory because it is not limited in principle by the requirement that the observed system be physically separated from the observing one. Applications are discussed.

  5. Generalized local emission tomography

    DOEpatents

    Katsevich, Alexander J.

    1998-01-01

    Emission tomography enables locations and values of internal isotope density distributions to be determined from radiation emitted from the whole object. In the method for locating the values of discontinuities, the intensities of radiation emitted from either the whole object or a region of the object containing the discontinuities are inputted to a local tomography function .function..sub..LAMBDA..sup.(.PHI.) to define the location S of the isotope density discontinuity. The asymptotic behavior of .function..sub..LAMBDA..sup.(.PHI.) is determined in a neighborhood of S, and the value for the discontinuity is estimated from the asymptotic behavior of .function..sub..LAMBDA..sup.(.PHI.) knowing pointwise values of the attenuation coefficient within the object. In the method for determining the location of the discontinuity, the intensities of radiation emitted from an object are inputted to a local tomography function .function..sub..LAMBDA..sup.(.PHI.) to define the location S of the density discontinuity and the location .GAMMA. of the attenuation coefficient discontinuity. Pointwise values of the attenuation coefficient within the object need not be known in this case.

  6. Ozone studies in the Paso del Norte region

    NASA Astrophysics Data System (ADS)

    Becerra-Davila, Fernando

    The Paso del Norte region forms the largest contiguous bi-national conglomerate on the US-Mexico border. With a combined population of around 2 million inhabitants, the Paso del Norte region is isolated, more than 500 km away from the nearest urban area of comparable size, thus making it an ideal location for air quality studies of an isolated urban environment. The meteorological conditions leading to a high ozone episode in this region, such as the historical ozone episode of June 2006, are analyzed. It is well known that stagnation and minimal winds, high temperatures, and pressure ridges over the region are conducive to high ozone episodes. In addition, the planetary boundary height is studied to understand its impact on high ozone episodes. Several studies report that ground level ozone non-attainment regulations could be caused not only by local emissions, but also by atmospheric transport. In this work the atmospheric advection of pollutants into the region is analyzed using HYSPLIT backward trajectories. Furthermore, a novel backward trajectory clustering technique is implemented for the summer of 2006. The "ozone weekend effect" (OWE) is a phenomenon by which in some geographical regions ambient ozone concentrations tend to be higher on weekends than on weekdays, despite the lower emissions of ozone precursors during those days. The observed local OWE has never previously been studied in terms of the photolysis rates of four of the main ozone precursors. In this research a novel method that allows the calculation of actinic fluxes, photolysis frequencies and photolysis rates with a high degree of accuracy and reliability has been developed. This method utilizes a combination of the experimental data available for this region in conjunction with a radiative transfer model (TUV model). Three weekend-weekday cases during summers 2006, 2009 and 2010 are studied in this work. In this research, the photolysis impact on the local OWE is studied. The results

  7. All Holdings Are Local: Archivists and Local Government Archives

    ERIC Educational Resources Information Center

    James, Russell D.

    2004-01-01

    Archivists working in repositories that contain local government records play an integral role within the local community. Unlike their colleagues in state, regional, or national repositories, the local government archivist concentrates on a small geographic region and demonstrates knowledge of the politics, history, and socio-economics of the…

  8. THz Local Oscillator Sources

    NASA Astrophysics Data System (ADS)

    Mehdi, Imran; Schlecht, Erich; Chattopadhyay, Goutam; Siegel, Peter H.

    Most operational Submillimeter-wave radio telescopes, both space borne and ground based, employ local oscillator sources based on Gunn diodes followed by whisker contacted Schottky multipliers. Enough progress, however, has been made on a number of fronts to conclude that next generation of radio telescopes that become operational in the new Millennium will have a different local oscillator (LO) generation architecture. MMIC power amplifiers with impressive gain in the Ka- to-W band have enabled the use of microwave synthesizers which can then be actively multiplied to provide a frequency agile power source beyond 100 GHz. This medium power millimeter source can then be amplified to enable efficient pumping of follow-on balanced multiplier stages. Input power to the multipliers can be further enhanced by power combining to achieve close to half a Watt at W-band. An 800 GHz three-stage multiplier chain, implemented this way has demonstrated a peak output power of 1 mW. A second advance in LO generation lies in the Schottky diode varactor technology. Planar Schottky diode multipliers have now been demonstrated up to 1500 GHz and it can be assumed that most of the future multiplier chains will be based on these robust devices rather than the whisker contacted diode of the past. The ability to produce planar GaAs diode chips deep into the THz range, with submicron dimensions, has opened up a wide range of circuit design space which can be taken advantage of to improve efficiency, bandwidth, and power handling capability of the multipliers. A third breakthrough has been the demonstration of photonic based LO sources utilizing GaAs photomixers. These sources, though not yet implemented in robust space borne missions, offer a number of advantages over their electronic counterparts, including extremely broad tuning, fiber coupled components, and solid-state implementation. Another development, which holds some promise, is the use of micro-machining technology to implement

  9. Modeling the Local Bubble

    NASA Astrophysics Data System (ADS)

    Cox, D. P.

    Modeling the Local Bubble is one of those activities fraught with danger. It is very easy to be too naive, to fail to consider the dependence of the model on assumptions about the nearby ambient state, or the likelihood of such a structure. It is similarly easy to become so caught up in the details of the vicinity that it is unclear where to begin a necessarily idealized modeling effort. And finally, it is important to remember that the data we have may in some cases be lying to us, and that we have not yet learned to read their facial expressions quite carefully enough. That said, I've tried in this paper to be helpful to those who may wish to take the risks. I surveyed the very most basic stories that the data seem to tell, and pointed out the standard coincidences that may be telling us a lot about what is happening, but may turn out once again to have been just coincidences. I've described 5 distinct conceptions that in one flavor or another pretty well survey the collection of mental images that have so far been carried by those who've attempted models. One may be right, or something entirely different may be more appropriate. It's at least vital to realize that a conception comes first, followed by a simplified model of details. I've also included a long list of questions directed at observers. Some have partial answers, some one wouldn't know today quite how to approach. But it is a list that students of the soft x-ray background, interstellar absorption lines, possible instrumentation, and the heliosphere may wish to review from time to time, just to see whether they can figure out how to be more helpful. There is another list for modelers, things the models must address, however-so-flimsily if necessary, because there are strong observational constraints (and stronger ones coming) on what can and cannot be present in the local ISM. To that I've added a few remarks concerning x-ray emission coming from beyond the Local Bubble, and another few on how x

  10. Líneas Vitales: Programas y servicios del NCI

    Cancer.gov

    Artículos y videos sobre los programas y servicios del Instituto Nacional del Cáncer de la serie educativa Líneas Vitales del NCI, la cual está dirigida especialmente a poblaciones multiculturales.

  11. Stable local oscillator microcircuit.

    SciTech Connect

    Brocato, Robert Wesley

    2006-10-01

    This report gives a description of the development of a Stable Local Oscillator (StaLO) Microcircuit. The StaLO accepts a 100MHz input signal and produces output signals at 1.2, 3.3, and 3.6 GHz. The circuit is built as a multi-chip module (MCM), since it makes use of integrated circuit technologies in silicon and lithium niobate as well as discrete passive components. The StaLO uses a comb generator followed by surface acoustic wave (SAW) filters. The comb generator creates a set of harmonic components of the 100MHz input signal. The SAW filters are narrow bandpass filters that are used to select the desired component and reject all others. The resulting circuit has very low sideband power levels and low phase noise (both less than -40dBc) that is limited primarily by the phase noise level of the input signal.

  12. Headphone localization of speech

    NASA Technical Reports Server (NTRS)

    Begault, Durand R.; Wenzel, Elizabeth M.

    1993-01-01

    Three-dimensional acoustic display systems have recently been developed that synthesize virtual sound sources over headphones based on filtering by head-related transfer functions (HRTFs), the direction-dependent spectral changes caused primarily by the pinnae. In this study, 11 inexperienced subjects judged the apparent spatial location of headphone-presented speech stimuli filtered with nonindividualized HRTFs. About half of the subjects 'pulled' their judgments toward either the median or the lateral-vertical planes, and estimates were almost always elevated. Individual differences were pronounced for the distance judgments; 15 to 46 percent of stimuli were heard inside the head, with the shortest estimates near the median plane. The results suggest that most listeners can obtain useful azimuth information from speech stimuli filtered by nonindividualized HRTFs. Measurements of localization error and reversal rates are comparable with a previous study that used broadband noise stimuli.

  13. The local minority game

    NASA Astrophysics Data System (ADS)

    Moelbert, S.; De Los Rios, P.

    2002-01-01

    Ecologists and economists try to explain collective behavior in terms of competitive systems of selfish individuals with the ability to learn from the past. Statistical physicists have been investigating models which might contribute to the understanding of the underlying mechanisms of these systems. During the last 3 yr one intuitive model, commonly referred to as the minority game (MG), has attracted considerable attention. Powerful yet simple, the minority game has produced encouraging results which can explain the temporal behavior of competitive systems. Here we switch the interest to the phenomena due to a distribution of the individuals in space. For analyzing these effects we modify the minority game and the local minority game (LMG) is introduced. We study the system both numerically and analytically, using the customary techniques already developed for the ordinary Minority Game.

  14. Sleep locally, act globally.

    PubMed

    Rattenborg, Niels C; Lima, Steven L; Lesku, John A

    2012-10-01

    In most animals, sleep is considered a global brain and behavioral state. However, recent intracortical recordings have shown that aspects of non-rapid eye movement (NREM) sleep and wakefulness can occur simultaneously in different parts of the cortex in mammals, including humans. Paradoxically, however, NREM sleep still manifests as a global behavioral shutdown. In this review, the authors examine this paradox from an evolutionary perspective. On the basis of strategic modeling, they suggest that in animals with brains composed of heavily interconnected and functionally interdependent units, a global regulator of sleep maintains the behavioral shutdown that defines sleep and thereby ensures that local use-dependent functions are performed in a safe and efficient manner. This novel perspective has implications for understanding deficits in human cognitive performance resulting from sleep deprivation, sleep disorders such as sleepwalking, changes in consciousness that occur during sleep, and the function of sleep itself. PMID:22572533

  15. Control del cáncer y salud mundial: noticia del Instituto Nacional del Cáncer (NCI)

    Cancer.gov

    En combinación con una reunión de alto nivel de las Naciones Unidas sobre enfermedades no transmisibles en países en vías de desarrollo, el doctor Harold Varmus, director del NCI, y el doctor Ted L. Trimble, del NCI, han publicado un comentario en Science

  16. Localized wave pulse experiments

    SciTech Connect

    Chambers, D L; Henderson, T L; Krueger, K L; Lewis, D K; Zilkowski, R N

    1999-06-01

    The Localized Wave project of the Strategic System Support Program has recently finished an experiment in cooperation with the Advanced SONAR group of the Applied Research Laboratory of the University of Texas at Austin. The purpose of the experiment was three-fold. They wanted to see if (1) the LW pulse could propagate over significant distances, to see if (2) a new type of array and drive system specifically designed for the pulse would increase efficiency over single frequency tone bursts, and to see if (3) the complexity of our 24 channel drivers resulted in better efficiency than a single equivalent pulse driving a piston. In the experiment, several LW pulses were launched from the Lake Travis facility and propagated over distances of either 100 feet or 600 feet, through a thermocline for the 600 foot measurements. The results show conclusively that the Localized Wave will propagate past the near field distance. The LW pulses resulted in extremely broad frequency band width pulses with narrow spatial beam patterns and unmeasurable side lobes. Their array gain was better than most tone bursts and further, were better than their equivalent piston pulses. This marks the first test of several Low Diffraction beams against their equivalent piston pulses, as well as the first propagation of LW pulses over appreciable distances. The LW pulse is now proven a useful tool in open water, rather than a laboratory curiosity. The experimental system and array were built by ARL, and the experiments were conducted by ARL staff on their standard test range. The 600 feet measurements were made at the farthest extent of that range.

  17. Going Local to Find Help

    MedlinePlus

    ... Home Current Issue Past Issues Cover Story: Traumatic Brain Injury Going Local to Find Help Past Issues / ... the time. From the MedlinePlus page on Traumatic Brain Injury, you can use Go Local to find ...

  18. Meeting the Local Skills Demand.

    ERIC Educational Resources Information Center

    Beccarelli, Catherine

    2000-01-01

    In Brittany, a project that integrates training and social development was designed to meet local labor market needs. Key features are innovative uses of training (pretraining, alternating training and work) and strong company involvement in local regeneration. (SK)

  19. Artinianness of local cohomology modules

    NASA Astrophysics Data System (ADS)

    Aghapournahr, Moharram; Melkersson, Leif

    2014-04-01

    Some uniform theorems on the artinianness of certain local cohomology modules are proven in a general situation. They generalize and imply previous results about the artinianness of some special local cohomology modules in the graded case.

  20. Going Local to Find Help

    MedlinePlus

    ... Bar Home Current Issue Past Issues Cover Story: Traumatic Brain Injury Going Local to Find Help Past Issues / Fall ... local health and social services for survivors of TBI is as important as knowing about the medical ...

  1. Genomic analysis of RNA localization

    PubMed Central

    Taliaferro, J Matthew; Wang, Eric T; Burge, Christopher B

    2014-01-01

    The localization of mRNAs to specific subcellular sites is widespread, allowing cells to spatially restrict and regulate protein production, and playing important roles in development and cellular physiology. This process has been studied in mechanistic detail for several RNAs. However, the generality or specificity of RNA localization systems and mechanisms that impact the many thousands of localized mRNAs has been difficult to assess. In this review, we discuss the current state of the field in determining which RNAs localize, which RNA sequences mediate localization, the protein factors involved, and the biological implications of localization. For each question, we examine prominent systems and techniques that are used to study individual messages, highlight recent genome-wide studies of RNA localization, and discuss the potential for adapting other high-throughput approaches to the study of localization. PMID:25483039

  2. Estimation of local spatial scale

    NASA Technical Reports Server (NTRS)

    Watson, Andrew B.

    1987-01-01

    The concept of local scale asserts that for a given class of psychophysical measurements, performance at any two visual field locations is equated by magnifying the targets by the local scale associated with each location. Local scale has been hypothesized to be equal to cortical magnification or alternatively to the linear density of receptors or ganglion cells. Here, it is shown that it is possible to estimate local scale without prior knowledge about the scale or its physiological basis.

  3. Local virial and tensor theorems.

    PubMed

    Cohen, Leon

    2011-11-17

    We show that for any wave function and potential the local virial theorem can always be satisfied 2K(r) = r·ΔV by choosing a particular expression for the local kinetic energy. In addition, we show that for each choice of local kinetic energy there are an infinite number of quasi-probability distributions which will generate the same expression. We also consider the local tensor virial theorem. PMID:21863837

  4. Local Molecular Orbitals from a Projection onto Localized Centers.

    PubMed

    Heßelmann, Andreas

    2016-06-14

    A localization method for molecular orbitals is presented which exploits the locality of the eigenfunctions associated with the largest eigenvalues of the matrix representation of spatially localized functions. Local molecular orbitals are obtained by a projection of the canonical orbitals onto the set of the eigenvectors which correspond to the largest eigenvalues of these matrices. Two different types of spatially localized functions were chosen in this work, a two-parameter smooth-step-type function and the weight functions determined by a Hirshfeld partitioning of the molecular volume. It is shown that the method can provide fairly local occupied molecular orbitals if the positions of the set of local functions are set to the molecular bond centers. The method can also yield reasonably well-localized virtual molecular orbitals, but here, a sensible choice of the positions of the functions are the atomic sites and the locality then depends more strongly on the shape of the set of local functions. The method is tested for a range of polypeptide molecules in two different conformations, namely, a helical and a β-sheet conformation. Futhermore, it is shown that an adequate locality of the occupied and virtual orbitals can also be obtained for highly delocalized systems. PMID:27164445

  5. Inference for local autocorrelations in locally stationary models

    PubMed Central

    Zhao, Zhibiao

    2014-01-01

    For non-stationary processes, the time-varying correlation structure provides useful insights into the underlying model dynamics. We study estimation and inferences for local autocorrelation process in locally stationary time series. Our constructed simultaneous confidence band can be used to address important hypothesis testing problems, such as whether the local autocorrelation process is indeed time-varying and whether the local autocorrelation is zero. In particular, our result provides an important generalization of the R function acf() to locally stationary Gaussian processes. Simulation studies and two empirical applications are developed. For the global temperature series, we find that the local autocorrelations are time-varying and have a “V” shape during 1910–1960. For the S&P 500 index, we conclude that the returns satisfy the efficient-market hypothesis whereas the magnitudes of returns show significant local autocorrelations. PMID:26097285

  6. Causal Learning with Local Computations

    ERIC Educational Resources Information Center

    Fernbach, Philip M.; Sloman, Steven A.

    2009-01-01

    The authors proposed and tested a psychological theory of causal structure learning based on local computations. Local computations simplify complex learning problems via cues available on individual trials to update a single causal structure hypothesis. Structural inferences from local computations make minimal demands on memory, require…

  7. Collecting and Using Local History.

    ERIC Educational Resources Information Center

    Miller, Marcia Muth

    The local history collection should contain: county histories; city and village histories; state and regional histories; anniversary booklets; company histories; local newspapers; local magazines; genealogies; family albums; diaries; journals, and letters; account books; club yearbooks; school annuals; telephone books, city directories and local…

  8. Local Government: The Learning Laboratory.

    ERIC Educational Resources Information Center

    Degelman, Charles, Ed.

    2001-01-01

    This issue of "Service-Learning Network" looks at the ways that service learning can transform local government into a learning laboratory for civic education. The first article, "Creating the Missing Link: Local Government, Service Learning, and Civic Education" (Todd Clark), introduces the issue. "Service Learning and Local Government" (Ann…

  9. Instantánea del melanoma

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el melanoma; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  10. Instantánea del linfoma

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el linfoma; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  11. Instantánea del mieloma

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el mieloma; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  12. Instantánea del sarcoma

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el sarcoma; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  13. Control of Cell Migration Through Mrna Localization and Local Translation

    PubMed Central

    Liao, Guoning; Mingle, Lisa; Van De Water, Livingston; Liu, Gang

    2014-01-01

    Cell migration plays an important role in many normal and pathological functions such as development, wound healing, immune defense and tumor metastasis. Polarized migrating cells exhibit asymmetric distribution of many cytoskeletal proteins which is believed to be critical for establishing and maintaining cell polarity and directional cell migration. To target these proteins to the site of function, cells use a variety of mechanisms such as protein transport and mRNA localization-mediated local protein synthesis. In contrast to the former which is intensively investigated and relatively well understood, the latter has been under-studied and relatively poorly understood. However, recent advances in the study of mRNA localization and local translation have demonstrated that mRNA localization and local translation are specific and effective ways for protein localization and are crucial for embryo development, neuronal function and many other cellular processes. There are excellent reviews on mRNA localization, transport and translation during development and other cellular processes. This review will focus on mRNA localization-mediated local protein biogenesis and its impact on somatic cell migration. PMID:25264217

  14. Local positioning system

    SciTech Connect

    Kyker, R.

    1995-07-25

    Navigation systems have been vital to transportation ever since man took to the air and sea. Early navigation systems utilized the sextant to navigate by starlight as well as the magnetic needle compass. As electronics and communication technologies improved, inertial navigation systems were developed for use in ships and missile delivery. These systems consisted of electronic compasses, gyro-compasses, accelerometers, and various other sensors. Recently, systems such as LORAN and the Global Positioning System (GPS) have utilized the properties of radio wave propagation to triangulate position. The Local Positioning System (LPS), described in this paper, is an implementation of a limited inertial navigation system designed to be used on a bicycle. LPS displays a cyclist`s current position relative to a starting location. This information is displayed in Cartesian-like coordinates. To accomplish this, LPS relies upon two sensors, an electronic compass sensor and a distance sensor. The compass sensor provides directional information while the distance sensor provides the distance traveled. This information yields a distance vector for each point in time which when summed produces the cyclist`s current position. LPS is microprocessor controlled and is designed for a range of less than 90 miles.

  15. Local Universe Dwarf Galaxies

    NASA Astrophysics Data System (ADS)

    Carignan, Claude

    2015-08-01

    One of the outstanding problems in cosmology is addressing the "small-scale crisis" and understanding structure formation at the smallest scales. Standard Lambda Cold Dark Matter cosmological simulations of Milky Way-size DM halos predict many more DM sub-halos than the number of dwarf galaxies observed. This is the so-called Missing Satellites Problem. The most popular interpretation of the Missing Satellites Problem is that the smallest dark matter halos in the universe are extremely inefficient at forming stars. The virialized extent of the Milky Way's halo should contain ~500 satellites, while only ˜100 satellites and dwarfs are observed in the whole Local Group. Despite the large amount of theoretical work and new optical observations, the discrepancy, even if reduced, still persists between observations and hierarchical models, regardless of the model parameters. It may be possible to find those isolated ultra-faint missing dwarf galaxies via their neutral gas component, which is one of the goals we are pursuing with the SKA precursor KAT-7 in South Africa, and soon with the SKA pathfinder MeerKAT.

  16. Fooled by local robustness.

    PubMed

    Sniedovich, Moshe

    2012-10-01

    One would have expected the considerable public debate created by Nassim Taleb's two best selling books on uncertainty, Fooled by Randomness and The Black Swan, to inspire greater caution to the fundamental difficulties posed by severe uncertainty. Yet, methodologies exhibiting an incautious approach to uncertainty have been proposed recently in a range of publications. So, the objective of this short note is to call attention to a prime example of an incautious approach to severe uncertainty that is manifested in the proposition to use the concept radius of stability as a measure of robustness against severe uncertainty. The central proposition of this approach, which is exemplified in info-gap decision theory, is this: use a simple radius of stability model to analyze and manage a severe uncertainty that is characterized by a vast uncertainty space, a poor point estimate, and a likelihood-free quantification of uncertainty. This short discussion serves then as a reminder that the generic radius of stability model is a model of local robustness. It is, therefore, utterly unsuitable for the treatment of severe uncertainty when the latter is characterized by a poor estimate of the parameter of interest, a vast uncertainty space, and a likelihood-free quantification of uncertainty. PMID:22384828

  17. Local quantum ergodic conjecture

    NASA Astrophysics Data System (ADS)

    Zambrano, Eduardo; Zapfe, W. P. Karel; Ozorio de Almeida, Alfredo M.

    2015-04-01

    The quantum ergodic conjecture equates the Wigner function for a typical eigenstate of a classically chaotic Hamiltonian with a δ function on the energy shell. This ensures the evaluation of classical ergodic expectations of simple observables, in agreement with Shnirelman's theorem, but this putative Wigner function violates several important requirements. Consequently, we transfer the conjecture to the Fourier transform of the Wigner function, that is, the chord function. We show that all the relevant consequences of the usual conjecture require only information contained within a small (Planck) volume around the origin of the phase space of chords: translations in ordinary phase space. Loci of complete orthogonality between a given eigenstate and its nearby translation are quite elusive for the Wigner function, but our local conjecture stipulates that their pattern should be universal for ergodic eigenstates of the same Hamiltonian lying within a classically narrow energy range. Our findings are supported by numerical evidence in a Hamiltonian exhibiting soft chaos. Heavily scarred eigenstates are remarkable counter-examples of the ergodic universal pattern.

  18. Impact of Local Sensors

    NASA Technical Reports Server (NTRS)

    Watson, Leela R.; Bauman, William H., III

    2008-01-01

    Forecasters at the 45th Weather Squadron (45 WS) use observations from the Kennedy Space Center (KSC) and Cape Canaveral Air Force Station (CCAFS) wind tower network and the CCAFS (XMR) daily rawinsonde observations (RAOB) to issue and verify wind advisories and warnings for operations. These observations are also used by the National Weather Service (NWS) Spaceflight Meteorology Group (SMG) in Houston, Texas and the NWS Melbourne, Florida (NWS MLB) to initialize their locally-run mesoscale models. In addition, SMG uses these observations to support shuttle landings at the Shuttle Landing Facility (SLF). Due to impending budget cuts, some or all of the KSC/CCAFS wind towers on the east-central Florida mainland and the XMR RAOBs may be eliminated. The locations of the mainland towers and XMR RAOB site are shown in Figure I. The loss of these data may impact the forecast capability of the 45 WS, SMG and NWS MLB. The AMU was tasked to conduct an objective independent modeling study to help determine how important these observations are to the accuracy of the model output used by the forecasters. To accomplish this, the Applied Meteorology Unit (AMU) performed a sensitivity study using the Weather Research and Forecasting (WRF) model initialized with and without KSC/CCAFS wind tower and XMR RAOB data.

  19. Measurement dependent locality

    NASA Astrophysics Data System (ADS)

    Pütz, Gilles; Gisin, Nicolas

    2016-05-01

    The demonstration and use of Bell-nonlocality, a concept that is fundamentally striking and is at the core of applications in device independent quantum information processing, relies heavily on the assumption of measurement independence, also called the assumption of free choice. The latter cannot be verified or guaranteed. In this paper, we consider a relaxation of the measurement independence assumption. We briefly review the results of Pütz et al (2014 Phys. Rev. Lett. 113 190402), which show that with our relaxation, the set of so-called measurement dependent local (MDL) correlations is a polytope, i.e. it can be fully described using a finite set of linear inequalities. Here we analyze this polytope, first in the simplest case of two parties with binary inputs and outputs, for which we give a full characterization. We show that partially entangled states are preferable to the maximally entangled state when dealing with measurement dependence in this scenario. We further present a method which transforms any Bell-inequality into an MDL inequality and give valid inequalities for the case of arbitrary number of parties as well as one for arbitrary number of inputs. We introduce the assumption of independent sources in the measurement dependence scenario and give a full analysis for the bipartite scenario with binary inputs and outputs. Finally, we establish a link between measurement dependence and another strong hindrance in certifying nonlocal correlations: nondetection events.

  20. All strategy is local.

    PubMed

    Greenwald, Bruce; Kahn, Judd

    2005-09-01

    The aim of strategy is to master a market environment by understanding and anticipating the actions of other economic agents, especially competitors. A firm that has some sort of competitive advantage-privileged access to customers, for instance--will have relatively few competitors to contend with, since potential competitors without an advantage, if they have their wits about them, will stay away. Thus, competitive advantages are actually barriers to entry and vice versa. In markets that are exposed, by contrast, competition is intense. If the incumbents have even brief success in earning greater than normal returns on investments, new entrants will swarm in to grab a share of the profits. Sooner or later, the additional competition will push returns as far down as the firms' costs of capital. For firms operating in such markets, the only choice is to forget about strategy and run the business as efficiently as possible. Barriers to entry are easier to maintain in a competitive arena that is "local", either in the geographic sense or in the sense of being limited to one product or a handful of related ones. The two most powerful competitive advantages-customer captivity and economies of scale-are more achievable and sustainable in circumscribed markets of this kind. Their opposites are the open markets and host of rivals that are features of globalization. Compapies entering such markets risk frittering away the advantages they secured on smaller playing fields.., Ifa company wants to grow but still obtain superior returns, the authors argue, the best strategy is to dominate a series of discrete but preferably contiguous markets and then expand only at their edges. WalMart's diminishing margins over the past 15 years are strong evidence of the danger of proceeding otherwise. PMID:16171214

  1. Locally finite dimensional Lie algebras

    NASA Astrophysics Data System (ADS)

    Hennig, Johanna

    We prove that in a locally finite dimensional Lie algebra L, any maximal, locally solvable subalgebra is the stabilizer of a maximal, generalized flag in an integrable, faithful module over L. Then we prove two structure theorems for simple, locally finite dimensional Lie algebras over an algebraically closed field of characteristic p which give sufficient conditions for the algebras to be of the form [K(R, *), K( R, *)] / (Z(R) ∩ [ K(R, *), K(R, *)]) for a simple, locally finite dimensional associative algebra R with involution *. Lastly, we explore the noncommutative geometry of locally simple representations of the diagonal locally finite Lie algebras sl(ninfinity), o( ninfinity), and sp(n infinity).

  2. Localized RNAs and their functions.

    PubMed

    Ding, D; Lipshitz, H D

    1993-10-01

    The eukaryotic cell is partitioned by membranes into spatially and functionally discrete subcellular organelles. In addition, the cytoplasm itself is partitioned into discrete subregions that carry out specific functions. Such compartmentation can be achieved by localizing proteins and RNAs to different subcellular regions. This review will focus on localized RNAs, with a particular emphasis on RNA localization mechanisms and on the possible biological functions of localization of these RNAs. In recent years, an increasing number of localized RNAs have been identified in a variety of cell types among many animal species. Emphasis here will be on localized RNAs in the most intensively studied systems-Drosophila and Xenopus eggs and early embryos. PMID:7506023

  3. Performing a local barrier operation

    DOEpatents

    Archer, Charles J; Blocksome, Michael A; Ratterman, Joseph D; Smith, Brian E

    2014-03-04

    Performing a local barrier operation with parallel tasks executing on a compute node including, for each task: retrieving a present value of a counter; calculating, in dependence upon the present value of the counter and a total number of tasks performing the local barrier operation, a base value, the base value representing the counter's value prior to any task joining the local barrier; calculating, in dependence upon the base value and the total number of tasks performing the local barrier operation, a target value of the counter, the target value representing the counter's value when all tasks have joined the local barrier; joining the local barrier, including atomically incrementing the value of the counter; and repetitively, until the present value of the counter is no less than the target value of the counter: retrieving the present value of the counter and determining whether the present value equals the target value.

  4. Performing a local barrier operation

    DOEpatents

    Archer, Charles J; Blocksome, Michael A; Ratterman, Joseph D; Smith, Brian E

    2014-03-04

    Performing a local barrier operation with parallel tasks executing on a compute node including, for each task: retrieving a present value of a counter; calculating, in dependence upon the present value of the counter and a total number of tasks performing the local barrier operation, a base value of the counter, the base value representing the counter's value prior to any task joining the local barrier; calculating, in dependence upon the base value and the total number of tasks performing the local barrier operation, a target value, the target value representing the counter's value when all tasks have joined the local barrier; joining the local barrier, including atomically incrementing the value of the counter; and repetitively, until the present value of the counter is no less than the target value of the counter: retrieving the present value of the counter and determining whether the present value equals the target value.

  5. Localized structure of Euglena bioconvection

    NASA Astrophysics Data System (ADS)

    Iima, Makoto; Shoji, Erika; Awazu, Akinori; Nishimori, Hiraku; Izumi, Shunsuke; Hiroshima University Collaboration

    2013-11-01

    Bioconvection of a suspension of Euglena gracilis, a photosensitive flagellate whose body length is approximately 50 micrometers, was experimentally studied. Under strong light intensity, Euglena has a negative phototaxis; they tend to go away from the light source. When the bright illumination is given from the bottom, a large scale spatio-temporal pattern is generated as a result of interaction between Euglena and surrounding flow. Recently, localized convection pattern had been reported, however, the generation process and interaction of the localized convection cells has not been analyzed. We performed experimental study to understand the localization mechanism, in particular, the onset of bioconvection and lateral localization behavior due to phototaxis. Experiments started from different initial condition suggests a bistability near the onset of the convection as binary fluid convection that also shows localized convection cells. Dynamics of localized convections cells, which is similar to the binary fluid convection case although the basic equations are not the same, is also reported.

  6. Global/Local Dynamic Models

    SciTech Connect

    Pfeffer, A; Das, S; Lawless, D; Ng, B

    2006-10-10

    Many dynamic systems involve a number of entities that are largely independent of each other but interact with each other via a subset of state variables. We present global/local dynamic models (GLDMs) to capture these kinds of systems. In a GLDM, the state of an entity is decomposed into a globally influenced state that depends on other entities, and a locally influenced state that depends only on the entity itself. We present an inference algorithm for GLDMs called global/local particle filtering, that introduces the principle of reasoning globally about global dynamics and locally about local dynamics. We have applied GLDMs to an asymmetric urban warfare environment, in which enemy units form teams to attack important targets, and the task is to detect such teams as they form. Experimental results for this application show that global/local particle filtering outperforms ordinary particle filtering and factored particle filtering.

  7. Localization algorithm for acoustic emission

    NASA Astrophysics Data System (ADS)

    Salinas, V.; Vargas, Y.; Ruzzante, J.; Gaete, L.

    2010-01-01

    In this paper, an iterative algorithm for localization of acoustic emission (AE) source is presented. The main advantage of the system is that it is independent of the 'ability' in the determination of signal level to triggering the signal by the researcher. The system was tested in cylindrical samples with an AE localized in a known position; the precision in the source determination was of about 2 mm, better than the precision obtained with classic localization algorithms (˜1 cm).

  8. Statistical signatures of photon localization

    PubMed

    Chabanov; Stoytchev; Genack

    2000-04-20

    The realization that electron localization in disordered systems (Anderson localization) is ultimately a wave phenomenon has led to the suggestion that photons could be similarly localized by disorder. This conjecture attracted wide interest because the differences between photons and electrons--in their interactions, spin statistics, and methods of injection and detection--may open a new realm of optical and microwave phenomena, and allow a detailed study of the Anderson localization transition undisturbed by the Coulomb interaction. To date, claims of three-dimensional photon localization have been based on observations of the exponential decay of the electromagnetic wave as it propagates through the disordered medium. But these reports have come under close scrutiny because of the possibility that the decay observed may be due to residual absorption, and because absorption itself may suppress localization. Here we show that the extent of photon localization can be determined by a different approach--measurement of the relative size of fluctuations of certain transmission quantities. The variance of relative fluctuations accurately reflects the extent of localization, even in the presence of absorption. Using this approach, we demonstrate photon localization in both weakly and strongly scattering quasi-one-dimensional dielectric samples and in periodic metallic wire meshes containing metallic scatterers, while ruling it out in three-dimensional mixtures of aluminium spheres. PMID:10786786

  9. Implementation of tsunami disaster prevention measures in the municipality of San Rafael del Sur, Nicaragua

    NASA Astrophysics Data System (ADS)

    Strauch, W.; Talavera, E.; Acosta, N.; Sanchez, M.; Mejia, E.

    2007-05-01

    The Nicaraguan Pacific coast presents considerable tsunami risk. On September 1, 1992, a tsunami caused enormous damage in the infrastructure and killed more than 170 people. A pilot project was conducted between 2006 and 2007 in the municipality of San Rafel del Sur, area of Masachapa, The project included multiple topics of tsunami prevention measures and considering the direct participation of the local population, as: -General education on disaster prevention, participative events; -Investigation of awareness level and information needs for different population groups; -Specific educational measures in the schools; -Publication of brochures, calendars, news paper articles, radio programs, TV spots -Development of local tsunami hazard maps, 1:5,000 scale; (based on previous regional tsunami hazard mapping projects and local participation) -Development of a tsunami warning plan; -Improvements of the national tsunami warning system. -Installation of sirens for tsunami warning -Installation of tsunami signs, indicating hazardous areas, evacuation routes, safe places; -Realization of evacuation drills in schools. Based on the experiences gained in Masachapa it is planned to run similar projects in other areas along the Nicaraguan Pacific coast. In the project participated the local municipality and local stakeholders of San Rafael del Sur, Ministry of Education, National Police, Nicaraguan Red Cross, Ministry of Health, Ministry of Tourism, Nicaraguan Geosciences Institute (INETER), National System for Disaster Prevention (SINAPRED), Swiss Agency for Development and Cooperation (SDC). It was financed by SDC and INETER.

  10. Produccion Gaseosa del Cometa Halley: Erupciones Y Fotodisociacion del Radical OH

    NASA Astrophysics Data System (ADS)

    Silva, A. M.; Mirabel, I. F.

    1990-11-01

    RESUMEN:En este trabajo informamos la detecci6n de 20 erupciones en la li'nea de =18cm (1667MHz) del radical OH en el Cometa Halley.Las observaciones incluyen todos los monitoreos existentes y se extienden desde 120 dias antes del perihelio hasta 90 dias despues.Se detectan bruscos crecimientos en el flujo medido,hasta un factor 1O,seguidos por decaimientos lentos asociados con la fotodisociaci6n del OH. Se obtuvieron valores para el tiempo de vida fotoquimico del OH y del H2O basandose en el modelo desarrollado previamente por Silva(1988). Esos tiempos de vida estan de acuerdo con predicciones teoricas y con las observaciones en el Ultravioleta, y los resultados, los que son fuertemente dependientes de la velocidad heliocentrica del Coineta (variando hasta un factor 6), han sido calculados para varios rangos de velocidad entre +28 y -28 km/seg. Key wo'L :

  11. Local State and Sector Theory in Local Quantum Physics

    NASA Astrophysics Data System (ADS)

    Ojima, Izumi; Okamura, Kazuya; Saigo, Hayato

    2016-06-01

    We define a new concept of local states in the framework of algebraic quantum field theory (AQFT). Local states are a natural generalization of states and give a clear vision of localization in the context of QFT. In terms of them, we can find a condition from which follows automatically the famous DHR selection criterion in DHR-DR theory. As a result, we can understand the condition as consequences of physically natural state preparations in vacuum backgrounds. Furthermore, a theory of orthogonal decomposition of completely positive (CP) maps is developed. It unifies a theory of orthogonal decomposition of states and order structure theory of CP maps. Using it, localized version of sectors is formulated, which gives sector theory for local states with respect to general reference representations.

  12. Local modes and localization in a multicomponent nonlinear lattice

    SciTech Connect

    Forinash, K.,; Cretegny, T.; Peyrard, M.,; Cretegny, T.,; Peyrard, M.,

    1997-04-01

    The existence, stability, and the conditions for the formation of nonlinear localized modes are investigated in a two-component one-dimensional lattice. In spite of their possible coupling with acoustic phonons, discrete breathers can exist as exact stable solutions or show a very slow decay. Nonlinear energy localization through energy exchange between localized excitations, exhibited previously for a one-component lattice [T. Dauxois and M. Peyrard, Phys. Rev. Lett. {bold 70}, 3935 (1993)] is more general and also valid in a multicomponent lattice. A self-localization of thermal fluctuations is also observed in such a system. The model is used to investigate the effect of bending proteins on DNA. It shows that a bend can collect the energy of moving localized modes or insulate one part of the molecule from transfers of energy from large amplitude excitations in other parts. {copyright} {ital 1997} {ital The American Physical Society}

  13. Local State and Sector Theory in Local Quantum Physics

    NASA Astrophysics Data System (ADS)

    Ojima, Izumi; Okamura, Kazuya; Saigo, Hayato

    2016-04-01

    We define a new concept of local states in the framework of algebraic quantum field theory (AQFT). Local states are a natural generalization of states and give a clear vision of localization in the context of QFT. In terms of them, we can find a condition from which follows automatically the famous DHR selection criterion in DHR-DR theory. As a result, we can understand the condition as consequences of physically natural state preparations in vacuum backgrounds. Furthermore, a theory of orthogonal decomposition of completely positive (CP) maps is developed. It unifies a theory of orthogonal decomposition of states and order structure theory of CP maps. Using it, localized version of sectors is formulated, which gives sector theory for local states with respect to general reference representations.

  14. PASO DEL NORTE ENVIRONMENTAL MONITOR

    EPA Science Inventory

    This project is developing an Internet web site and associated community linkages to provide relevant-time air quality and local traffic and transit information, in English and Spanish, to the international communities of El Paso, Texas, Sunland Park, New Mexico and Ciud...

  15. How Just is Local Justice?

    ERIC Educational Resources Information Center

    Schultze, William A.

    1975-01-01

    Studies of criminal law practices suggest that variations in treatment from locality to locality depend on the judicial culture of the particular city, socioeconomic status of the accused, and the attitudes and actions of the police. This journal is available from the Law in American Society Foundation, 33 North LaSalle Street, Suite 1700; Chicago…

  16. Student Papers in Local History.

    ERIC Educational Resources Information Center

    Johnson County Community Coll., Overland Park, KS. Johnson County Center for Local History.

    Thirteen papers on Kansas and Johnson County, Kansas history are presented. The papers were written by students in a course at the Johnson County Center for Local History or for independent study in local history. The papers are: "Conditions and Construction of Gardner Lake"; "The History of St. Joseph's Church, Shawnee, Kansas"; "Patrons of…

  17. Hendrix College Local Food Project.

    ERIC Educational Resources Information Center

    Valen, Gary L.

    1992-01-01

    By purchasing locally grown foods, Hendrix College (Arkansas) has found it can offer better nutrition, cut environmental damage, and spur economic development. The Local Food Project has reduced the amount of food purchased out of state from 90-70 percent, and is aiming for 50 percent in three years. Student participation is integral. (Author/MSE)

  18. Developing Local Lifelong Guidance Strategies.

    ERIC Educational Resources Information Center

    Watts, A. G.; Hawthorn, Ruth; Hoffbrand, Jill; Jackson, Heather; Spurling, Andrea

    1997-01-01

    Outlines the background, rationale, methodology, and outcomes of developing local lifelong guidance strategies in four geographic areas. Analyzes the main components of the strategies developed and addresses a number of issues relating to the process of strategy development. Explores implications for parallel work in other localities. (RJM)

  19. Local Oscillatory Rheology from Echography

    NASA Astrophysics Data System (ADS)

    Saint-Michel, Brice; Gibaud, Thomas; Leocmach, Mathieu; Manneville, Sébastien

    2016-03-01

    Local oscillatory rheology from echography consists of a traditional rheology experiment synchronized with high-frequency ultrasonic imaging which gives access to the local material response to oscillatory shear. Besides classical global rheological quantities, this method provides quantitative time-resolved information on the local displacement across the entire gap of the rheometer. From the local displacement response, we compute and decompose the local strain in its Fourier components and measure the spatially resolved viscoelastic moduli. After benchmarking our method on homogeneous Newtonian fluids and soft solids, we demonstrate that this technique is well suited to characterize spatially heterogeneous samples, wall slip, and the emergence of nonlinearity under large-amplitude oscillatory stress in soft materials.

  20. A local coastal adaptation pathway

    NASA Astrophysics Data System (ADS)

    Barnett, J.; Graham, S.; Mortreux, C.; Fincher, R.; Waters, E.; Hurlimann, A.

    2014-12-01

    Local governments are not adapting to sea-level rise because it is difficult to build consensus on the need for change and the best way to implement it. In theory, adaptation pathways can resolve this impasse. Adaptation pathways are a sequence of linked strategies that are triggered by a change in environmental conditions, and in which initial decisions can have low regrets and preserve options for future generations. We report on a project that sought to empirically test the relevance and feasibility of a local pathway for adapting to sea-level rise. We find that triggers of change that have social impacts are salient to local people, and developing a local adaptation pathway helps build consensus among diverse constituencies. Our results show that adaptation pathways are feasible at the local scale, offering a low-risk, low-cost way to begin the long process of adaptation to sea-level rise.

  1. Gonadal dysgenesis in del (18p) syndrome

    SciTech Connect

    Telvi, L.; Ion, A.; Fouquet, F.

    1995-07-17

    We report on a girl with syndromal gonadal dysgenesis and a de novo del (18p). Genetic factors controlling gonadal development are located not only on the X chromosome, but also on autosomes. The present case suggests that one of these genes is situated on 18p. We conclude that patients with del (18p) syndrome should be evaluated for gonadal dysgenesis. 16 refs., 3 figs.

  2. Localization scheme for relativistic spinors

    NASA Astrophysics Data System (ADS)

    Ciupka, J.; Hanrath, M.; Dolg, M.

    2011-12-01

    A new method to determine localized complex-valued one-electron functions in the occupied space is presented. The approach allows the calculation of localized orbitals regardless of their structure and of the entries in the spinor coefficient matrix, i.e., one-, two-, and four-component Kramers-restricted or unrestricted one-electron functions with real or complex expansion coefficients. The method is applicable to localization schemes that maximize (or minimize) a functional of the occupied spinors and that use a localization operator for which a matrix representation is available. The approach relies on the approximate joint diagonalization (AJD) of several Hermitian (symmetric) matrices which is utilized in electronic signal processing. The use of AJD in this approach has the advantage that it allows a reformulation of the localization criterion on an iterative 2 × 2 pair rotating basis in an analytical closed form which has not yet been described in the literature for multi-component (complex-valued) spinors. For the one-component case, the approach delivers the same Foster-Boys or Pipek-Mezey localized orbitals that one obtains from standard quantum chemical software, whereas in the multi-component case complex-valued spinors satisfying the selected localization criterion are obtained. These localized spinors allow the formulation of local correlation methods in a multi-component relativistic framework, which was not yet available. As an example, several heavy and super-heavy element systems are calculated using a Kramers-restricted self-consistent field and relativistic two-component pseudopotentials in order to investigate the effect of spin-orbit coupling on localization.

  3. An Open Localization and Local Communication Embodied Sensor

    PubMed Central

    Gutiérrez, Álvaro; Campo, Alexandre; Dorigo, Marco; Amor, Daniel; Magdalena, Luis; Félix, Monasterio-Huelin

    2008-01-01

    In this paper we describe a localization and local communication system which allows situated agents to communicate locally, obtaining at the same time both the range and the bearing of the emitter without the need of any centralized control or any external reference. The system relies on infrared communications with frequency modulation and is composed of two interconnected modules for data and power measurement. Thanks to the open hardware license under which it is released, the research community can easily replicate the system at a low cost and/or adapt it for applications in sensor networks and in robotics.

  4. Local Anesthetic-Induced Neurotoxicity

    PubMed Central

    Verlinde, Mark; Hollmann, Markus W.; Stevens, Markus F.; Hermanns, Henning; Werdehausen, Robert; Lirk, Philipp

    2016-01-01

    This review summarizes current knowledge concerning incidence, risk factors, and mechanisms of perioperative nerve injury, with focus on local anesthetic-induced neurotoxicity. Perioperative nerve injury is a complex phenomenon and can be caused by a number of clinical factors. Anesthetic risk factors for perioperative nerve injury include regional block technique, patient risk factors, and local anesthetic-induced neurotoxicity. Surgery can lead to nerve damage by use of tourniquets or by direct mechanical stress on nerves, such as traction, transection, compression, contusion, ischemia, and stretching. Current literature suggests that the majority of perioperative nerve injuries are unrelated to regional anesthesia. Besides the blockade of sodium channels which is responsible for the anesthetic effect, systemic local anesthetics can have a positive influence on the inflammatory response and the hemostatic system in the perioperative period. However, next to these beneficial effects, local anesthetics exhibit time and dose-dependent toxicity to a variety of tissues, including nerves. There is equivocal experimental evidence that the toxicity varies among local anesthetics. Even though the precise order of events during local anesthetic-induced neurotoxicity is not clear, possible cellular mechanisms have been identified. These include the intrinsic caspase-pathway, PI3K-pathway, and MAPK-pathways. Further research will need to determine whether these pathways are non-specifically activated by local anesthetics, or whether there is a single common precipitating factor. PMID:26959012

  5. Local Anesthetic-Induced Neurotoxicity.

    PubMed

    Verlinde, Mark; Hollmann, Markus W; Stevens, Markus F; Hermanns, Henning; Werdehausen, Robert; Lirk, Philipp

    2016-01-01

    This review summarizes current knowledge concerning incidence, risk factors, and mechanisms of perioperative nerve injury, with focus on local anesthetic-induced neurotoxicity. Perioperative nerve injury is a complex phenomenon and can be caused by a number of clinical factors. Anesthetic risk factors for perioperative nerve injury include regional block technique, patient risk factors, and local anesthetic-induced neurotoxicity. Surgery can lead to nerve damage by use of tourniquets or by direct mechanical stress on nerves, such as traction, transection, compression, contusion, ischemia, and stretching. Current literature suggests that the majority of perioperative nerve injuries are unrelated to regional anesthesia. Besides the blockade of sodium channels which is responsible for the anesthetic effect, systemic local anesthetics can have a positive influence on the inflammatory response and the hemostatic system in the perioperative period. However, next to these beneficial effects, local anesthetics exhibit time and dose-dependent toxicity to a variety of tissues, including nerves. There is equivocal experimental evidence that the toxicity varies among local anesthetics. Even though the precise order of events during local anesthetic-induced neurotoxicity is not clear, possible cellular mechanisms have been identified. These include the intrinsic caspase-pathway, PI3K-pathway, and MAPK-pathways. Further research will need to determine whether these pathways are non-specifically activated by local anesthetics, or whether there is a single common precipitating factor. PMID:26959012

  6. Local and Non-⁠local Mechanisms of Polar Amplification

    NASA Astrophysics Data System (ADS)

    Alexeev, V. A.; Jackson, C. H.

    2015-12-01

    Polar amplification (PA) is a prominent feature of currently observed and predicted future climate change suggested by both observations and models. Surface albedo feedback (SAF) has been shown to contribute prominently to the currently observed PA along with other mechanisms, e.g. involving atmospheric heat transport. SAF is believed to be a strong positive local feedback, while the atmospheric heat transport makes the connection between the Arctic and the low latitudes non-local. We will discuss several PA mechanisms and feedbacks suggested by different researchers. We will also discuss a more general method of feedback analysis that results in feedback and gain matrices. These matrices generalize (both globally and locally) the classically defined numerical gains and feedback factors and are independent of the applied forcing. The gain matrix, in particular, is shown to reveal, under any forcing scenario, the global pattern by which a given feedback process amplifies or dampens fixed-feedback temperature anomalies. Moreover, in the case of a feedback process that is not purely a function of local temperature, these matrices will show the degree to which this "local feedback process" depends on non-local perturbations. We apply this method in the context of a simple box model as well as a one-dimensional energy balance climate model.

  7. Quantum localization of classical mechanics

    NASA Astrophysics Data System (ADS)

    Batalin, Igor A.; Lavrov, Peter M.

    2016-07-01

    Quantum localization of classical mechanics within the BRST-BFV and BV (or field-antifield) quantization methods are studied. It is shown that a special choice of gauge fixing functions (or BRST-BFV charge) together with the unitary limit leads to Hamiltonian localization in the path integral of the BRST-BFV formalism. In turn, we find that a special choice of gauge fixing functions being proportional to extremals of an initial non-degenerate classical action together with a very special solution of the classical master equation result in Lagrangian localization in the partition function of the BV formalism.

  8. Local governments LANDSAT applications program

    NASA Technical Reports Server (NTRS)

    1983-01-01

    The approach used to develop the internal capabilities of local governments to handle and evaluate LANDSAT data included remote sensing training, development of a low-cost digital image processing system, and technical assistance. Cost sharing, program management and coordination, and networking were also employed to address problems related to land use, water resources, environmental assessment, and air quality as experienced by urban planners. Local experiences gained in Atlanta, Georgia; Henrico County, Virginia; Oklahoma City; Oklahoma; and San Jose, California are described. Policy recommendations formulated for transferring remote sensing technologies to local governments are included.

  9. Stress Localization in Elastic Shells

    NASA Astrophysics Data System (ADS)

    Selden, Sarah; Evans, Arthur; Bende, Nakul; Hayward, Ryan; Santangelo, Christian

    Upon indentation, thin shells react by localizing strain energy in polygonal structures as opposed to a uniform axisymmetric distribution. While the formation of these localized structures are well-characterized for perfect shells, a change in shell thickness or the introduction of a crease fundamentally changes the nature of the shell deformation. We perform finite element simulations, in tandem with experiments to explore the effect of different shell geometries on the energy landscape. We find that the crease induces a new symmetry-breaking localization that does not appear in perfect shells, and we explore the deformation characteristics of the creased shell over a wide range of crease radii, and crease orientations.

  10. Speeding up local correlation methods

    NASA Astrophysics Data System (ADS)

    Kats, Daniel

    2014-12-01

    We present two techniques that can substantially speed up the local correlation methods. The first one allows one to avoid the expensive transformation of the electron-repulsion integrals from atomic orbitals to virtual space. The second one introduces an algorithm for the residual equations in the local perturbative treatment that, in contrast to the standard scheme, does not require holding the amplitudes or residuals in memory. It is shown that even an interpreter-based implementation of the proposed algorithm in the context of local MP2 method is faster and requires less memory than the highly optimized variants of conventional algorithms.

  11. Speeding up local correlation methods

    SciTech Connect

    Kats, Daniel

    2014-12-28

    We present two techniques that can substantially speed up the local correlation methods. The first one allows one to avoid the expensive transformation of the electron-repulsion integrals from atomic orbitals to virtual space. The second one introduces an algorithm for the residual equations in the local perturbative treatment that, in contrast to the standard scheme, does not require holding the amplitudes or residuals in memory. It is shown that even an interpreter-based implementation of the proposed algorithm in the context of local MP2 method is faster and requires less memory than the highly optimized variants of conventional algorithms.

  12. Advanced local area network concepts

    NASA Technical Reports Server (NTRS)

    Grant, Terry

    1985-01-01

    Development of a good model of the data traffic requirements for Local Area Networks (LANs) onboard the Space Station is the driving problem in this work. A parameterized workload model is under development. An analysis contract has been started specifically to capture the distributed processing requirements for the Space Station and then to develop a top level model to simulate how various processing scenarios can handle the workload and what data communication patterns result. A summary of the Local Area Network Extendsible Simulator 2 Requirements Specification and excerpts from a grant report on the topological design of fiber optic local area networks with application to Expressnet are given.

  13. Localized functionalization of single nanopores

    SciTech Connect

    Nilsson, J; Lee, J I; Ratto, T V; Letant, S E

    2005-09-12

    We demonstrate the localization of chemical functionality at the entrance of single nanopores for the first time by using the controlled growth of an oxide ring. Nanopores were fabricated by Focused Ion Beam machining on silicon platforms, locally derivatized by ion beam assisted oxide deposition, and further functionalized with DNA probes via silane chemistry. Ionic current recorded through single nanopores at various stages of the fabrication process demonstrated that the apertures can be locally functionalized with DNA probes. Future applications for this functional platform include the selective detection of biological organisms and molecules by ionic current blockade measurements.

  14. Intertextual Sexual Politics: Illness and Desire in Enrique Gomez Carrillo's "Del amor", "del dolor y del vicio" and Aurora Caceres's "La rosa muerta"

    ERIC Educational Resources Information Center

    LaGreca, Nancy

    2012-01-01

    This study explores the intertextuality between Aurora Caceres's "La rosa muerta" (1914) and the novel "Del amor, del dolor y del vicio" (1898) by her ex-husband, Enrique Gomez Carrillo. Caceres strategically mentions Gomez Carrillo's novel in "La rosa muerta" to invite a reading of her work in dialogue with his. Both narratives follow the sexual…

  15. Recovering entanglement by local operations

    SciTech Connect

    D’Arrigo, A.; Lo Franco, R.; Benenti, G.; Paladino, E.; Falci, G.

    2014-11-15

    We investigate the phenomenon of bipartite entanglement revivals under purely local operations in systems subject to local and independent classical noise sources. We explain this apparent paradox in the physical ensemble description of the system state by introducing the concept of “hidden” entanglement, which indicates the amount of entanglement that cannot be exploited due to the lack of classical information on the system. For this reason this part of entanglement can be recovered without the action of non-local operations or back-transfer process. For two noninteracting qubits under a low-frequency stochastic noise, we show that entanglement can be recovered by local pulses only. We also discuss how hidden entanglement may provide new insights about entanglement revivals in non-Markovian dynamics.

  16. Local Area Networks (The Printout).

    ERIC Educational Resources Information Center

    Aron, Helen; Balajthy, Ernest

    1989-01-01

    Describes the Local Area Network (LAN), a project in which students used LAN-based word processing and electronic mail software as the center of a writing process approach. Discusses the advantages and disadvantages of networking. (MM)

  17. Local reaction kinetics by imaging

    NASA Astrophysics Data System (ADS)

    Suchorski, Yuri; Rupprechter, Günther

    2016-01-01

    In the present contribution we present an overview of our recent studies using the "kinetics by imaging" approach for CO oxidation on heterogeneous model systems. The method is based on the correlation of the PEEM image intensity with catalytic activity: scaled down to the μm-sized surface regions, such correlation allows simultaneous local kinetic measurements on differently oriented individual domains of a polycrystalline metal-foil, including the construction of local kinetic phase diagrams. This allows spatially- and component-resolved kinetic studies and, e.g., a direct comparison of inherent catalytic properties of Pt(hkl)- and Pd(hkl)-domains or supported μm-sized Pd-powder agglomerates, studies of the local catalytic ignition and the role of defects and grain boundaries in the local reaction kinetics.

  18. Fermion localization on thick branes

    SciTech Connect

    Melfo, Alejandra; Pantoja, Nelson; Tempo, Jose David

    2006-02-15

    We consider chiral fermion confinement in scalar thick branes, which are known to localize gravity, coupled through a Yukawa term. The conditions for the confinement and their behavior in the thin-wall limit are found for various different BPS branes, including double walls and branes interpolating between different AdS{sub 5} spacetimes. We show that only one massless chiral mode is localized in all these walls, whenever the wall thickness is keep finite. We also show that, independently of wall's thickness, chiral fermionic modes cannot be localized in dS{sub 4} walls embedded in a M{sub 5} spacetime. Finally, massive fermions in double wall spacetimes are also investigated. We find that, besides the massless chiral mode localization, these double walls support quasilocalized massive modes of both chiralities.

  19. Local reaction kinetics by imaging☆

    PubMed Central

    Suchorski, Yuri; Rupprechter, Günther

    2016-01-01

    In the present contribution we present an overview of our recent studies using the “kinetics by imaging” approach for CO oxidation on heterogeneous model systems. The method is based on the correlation of the PEEM image intensity with catalytic activity: scaled down to the μm-sized surface regions, such correlation allows simultaneous local kinetic measurements on differently oriented individual domains of a polycrystalline metal-foil, including the construction of local kinetic phase diagrams. This allows spatially- and component-resolved kinetic studies and, e.g., a direct comparison of inherent catalytic properties of Pt(hkl)- and Pd(hkl)-domains or supported μm-sized Pd-powder agglomerates, studies of the local catalytic ignition and the role of defects and grain boundaries in the local reaction kinetics. PMID:26865736

  20. Local Authority and Town Planning.

    ERIC Educational Resources Information Center

    Duder, Bruce

    1987-01-01

    Provides an overview and definition of local authority and town planning in New Zealand. Demonstrates the relevance of planning matters to the teaching of geography. Reviews objectives of geography and specific planning methods used in several districts. (BR)

  1. Composition of Local Galactic Medium

    NASA Video Gallery

    Animated view showing the neon to oxygen ratio in the neutral gas of the local cloud, as obtained with IBEX, in comparison with the ratio for the Sun and the Milky Way galaxy. There is much less ox...

  2. Dynamical domain wall and localization

    NASA Astrophysics Data System (ADS)

    Toyozato, Yuta; Higuchi, Masafumi; Nojiri, Shin'ichi

    2016-03-01

    Based on the previous works (Toyozato et al., 2013 [24]; Higuchi and Nojiri, 2014 [25]), we investigate the localization of the fields on the dynamical domain wall, where the four-dimensional FRW universe is realized on the domain wall in the five-dimensional space-time. Especially we show that the chiral spinor can localize on the domain wall, which has not been succeeded in the past works as the seminal work in George et al. (2009) [23].

  3. Local Realism of Macroscopic Correlations

    NASA Astrophysics Data System (ADS)

    Ramanathan, R.; Paterek, T.; Kay, A.; Kurzyński, P.; Kaszlikowski, D.

    2011-08-01

    We identify conditions under which correlations resulting from quantum measurements performed on macroscopic systems (systems composed of a number of particles of the order of the Avogadro number) can be described by local realism. We argue that the emergence of local realism at the macroscopic level is caused by an interplay between the monogamous nature of quantum correlations and the fact that macroscopic measurements do not reveal properties of individual particles.

  4. Mitochondrial DNA diversity of feral pigs from Karukinka Natural Park, Tierra del Fuego Island, Chile.

    PubMed

    Aravena, P; Skewes, O; Gouin, N

    2015-01-01

    Control or eradication of exotic species is one of the greatest challenges facing biodiversity and ecosystem conservation. Domestic pigs (Sus scrofa domestica) were released and became feral in the southern region of Chilean Tierra del Fuego Island in the 1900s. Currently, they inhabit part of Karukinka Natural Park, an area of global conservation concern. To gain insight into the control of this invasive species, we analyzed genetic variation in the mitochondrial DNA control region to determine the origin and population subdivision of feral pigs in Tierra del Fuego. Sequences from a sample of 42 feral pigs, 10 domestic pigs from local farms, and references from other countries and commercial breeds revealed 2 highly differentiated populations, 1 in the western and the other in the eastern area of the park, each harboring a different haplotype, suggesting no connectivity between populations. Comparison of these haplotypes with reference sequences from other countries and commercial breeds indicated that feral pigs from Chilean Tierra del Fuego are of European origin, very likely from 2 separate introduction events. The haplotype found in the western feral population was also identified in domestic pigs from a farm. This raises concerns regarding the possible connectivity between stocks from local farms and the wild population. Based on these results, we recommend the development of strategies for controlling the population of this invasive species in Karukinka Natural Park. PMID:25966196

  5. Promoting local management in groundwater

    NASA Astrophysics Data System (ADS)

    van Steenbergen, Frank

    2006-03-01

    There is a strong case for making greater effort to promote local groundwater management—in addition to other measures that regulate groundwater use. Though scattered, there are several examples—from India, Pakistan, Yemen and Egypt—where groundwater users effectively self-imposed restrictions on the use of groundwater. There are a number of recurrent themes in such spontaneously-developed examples of local regulation: the importance of not excluding potential users; the importance of simple, low transaction cost rules; the power of correct and accessible hydrogeological information; the possibility of making more use of demand and supply management strategies; and the important supportive role of local governments. The case is made, using examples, for actively promoting local groundwater management as an important element in balancing groundwater uses. Two programmes for promoting local groundwater management in South India are described—one focussing on participatory hydrological monitoring, and one focussing on micro-resource planning and training. In both cases the response was very positive and the conclusion is that promoting local groundwater regulation is not difficult, costly or sensitive and can reach the necessary scale quickly.

  6. ``Campo del Cielo'' Meteorites: Astronomical Heritage and Cultural Colonialism

    NASA Astrophysics Data System (ADS)

    López, Alejandro Martín; Altman, Agustina

    2012-09-01

    In the province of Chaco, Argentina, there is a very unique dispersion of metallic meteorites called ``Campo del Cielo''. One of the meteoric fragments of this dispersion, the meteorite called ``El Chaco'', consisting of 37 tons, is the second heaviest in the world. These meteorites are of great importance to the worldview of the Moqoit, aboriginal people that inhabit this region. For the local Creole population the meteorites are also relevant, that's why they have being cited in numerous documents and reports since the colonial period. During the first months of 2012, two Argentine artists and the Artistic Director of the German contemporary art exhibition called dOCUMENTA (13) tried to move ``El Chaco'' meteorite to Germany in order to exhibit it as an artistic object. Due to the fact that moving the meteorite could have a negative impact according to the Moqoit cosmology and that they were not able to participate in the decision they begun a manifestation against the movement of El Chaco. The opposition made by aboriginal communities and experts in cultural astronomy was able to stop the transfer. The whole process and its impact on the local community have promoted a deep discussion about art, science and cultural colonialism. In this paper we aim to address this debate and its consequences. This will allow us to think about contemporary forms of colonialism that are hidden in many scientific and artistic projects. Furthermore, we aim to debate about the most effective ways of protecting astronomical heritage in the Third World.

  7. Seismicity following the 1985 eruption of Nevado del Ruiz, Colombia

    USGS Publications Warehouse

    Zollweg, J.E.

    1990-01-01

    Over 200 of the best-recorded earthquakes occurring near Nevado del Ruiz, Colombia, between December 1985 and May 1986 are examined for spatial patterns, information on local stress orientations, and evidence for seismogenic structures that may be related to magma-transport processes. These earthquakes occurred following the devastating eruption of November 13, 1985. Earthquake activity that is probably related to the volcanic system occurs over a large area, of the order of 50 km2. A pattern of earthquakes beneath the southern half of Ruiz may be the expression of a conduit system, but evidence is inconclusive due to low spatial resolution of most hypocenters. Epicenter and first-motion plots suggest most earthquakes occur on small faults of varying orientation. Most seismicity during this time period was unrelated to mapped faults, including some with Holocene offsets, except for the Villamaria Fault near Ruiz's northeast sector. Composite focal mechanisms show a variation of nearly 90?? in the strike of T-axes and indicate Ruiz is in a zone of local extension. ?? 1990.

  8. Local cloning of entangled states

    SciTech Connect

    Gheorghiu, Vlad; Yu Li; Cohen, Scott M.

    2010-08-15

    We investigate the conditions under which a set S of pure bipartite quantum states on a DxD system can be locally cloned deterministically by separable operations, when at least one of the states is full Schmidt rank. We allow for the possibility of cloning using a resource state that is less than maximally entangled. Our results include that: (i) all states in S must be full Schmidt rank and equally entangled under the G-concurrence measure, and (ii) the set S can be extended to a larger clonable set generated by a finite group G of order |G|=N, the number of states in the larger set. It is then shown that any local cloning apparatus is capable of cloning a number of states that divides D exactly. We provide a complete solution for two central problems in local cloning, giving necessary and sufficient conditions for (i) when a set of maximally entangled states can be locally cloned, valid for all D; and (ii) local cloning of entangled qubit states with nonvanishing entanglement. In both of these cases, we show that a maximally entangled resource is necessary and sufficient, and the states must be related to each other by local unitary 'shift' operations. These shifts are determined by the group structure, so need not be simple cyclic permutations. Assuming this shifted form and partially entangled states, then in D=3 we show that a maximally entangled resource is again necessary and sufficient, while for higher-dimensional systems, we find that the resource state must be strictly more entangled than the states in S. All of our necessary conditions for separable operations are also necessary conditions for local operations and classical communication (LOCC), since the latter is a proper subset of the former. In fact, all our results hold for LOCC, as our sufficient conditions are demonstrated for LOCC, directly.

  9. Localization and Quantitative Co-localization of Enamelin with Amelogenin

    PubMed Central

    Gallon, Victoria; Chen, Lisha; Yang, Xiudong; Moradian-Oldak, Janet

    2013-01-01

    Enamelin and amelogenin are vital proteins in enamel formation. The cooperative function of these two proteins controls crystal nucleation and morphology in vitro. We quantitatively analyzed the co-localization between enamelin and amelogenin by confocal microscopy and using two antibodies, one raised against a sequence in the porcine 32 kDa enamelin region and the other raised against full-length recombinant mouse amelogenin. We further investigated the interaction of the porcine 32 kDa enamelin and recombinant amelogenin using immuno-gold labeling. This study reports the quantitative co-localization results for postnatal days 1, 2, 3, 4, 5, 6, 7 and 8 mandibular mouse molars. We show that amelogenin and enamelin are secreted into the extracellular matrix on the cuspal slopes of the molars at day 1 and that secretion continues to at least day 8. Quantitative co-localization analysis (QCA) was performed in several different configurations using large (45 μm height, 33 μm width) and small (7 μm diameter) regions of interest to elucidate any patterns. Co-localization patterns in day 8 samples revealed that enamelin and amelogenin co-localize near the secretory face of the ameloblasts and appear to be secreted approximately in a 1:1 ratio. The degree of co-localization decreases as the enamel matures, both along the secretory face of ameloblasts and throughout the entire thickness of the enamel. Immuno-reactivity against enamelin is concentrated along the secretory face of ameloblasts, supporting the theory that this protein together with amelogenin is intimately involved in mineral induction at the beginning of enamel formation. PMID:23563189

  10. Insights into the spurious long-range nature of local rs-dependent non-local exchange-correlation kernels

    DOE PAGESBeta

    Lu, Deyu

    2016-08-05

    A systematic route to go beyond the exact exchange plus random phase approximation (RPA) is to include a physical exchange-correlation kernel in the adiabatic-connection fluctuation-dissipation theorem. Previously, [D. Lu, J. Chem. Phys. 140, 18A520 (2014)], we found that non-local kernels with a screening length depending on the local Wigner-Seitz radius, rs(r), suffer an error associated with a spurious long-range repulsion in van der Waals bounded systems, which deteriorates the binding energy curve as compared to RPA. Here, we analyze the source of the error and propose to replace rs(r) by a global, average rs in the kernel. Exemplary studies withmore » the Corradini, del Sole, Onida, and Palummo kernel show that while this change does not affect the already outstanding performance in crystalline solids, using an average rs significantly reduces the spurious long-range tail in the exchange-correlation kernel in van der Waals bounded systems. Finally, when this method is combined with further corrections using local dielectric response theory, the binding energy of the Kr dimer is improved three times as compared to RPA.« less

  11. Insights into the spurious long-range nature of local rs-dependent non-local exchange-correlation kernels

    NASA Astrophysics Data System (ADS)

    Lu, Deyu

    2016-08-01

    A systematic route to go beyond the exact exchange plus random phase approximation (RPA) is to include a physical exchange-correlation kernel in the adiabatic-connection fluctuation-dissipation theorem. In the previous study [D. Lu, J. Chem. Phys. 140, 18A520 (2014)], we found that non-local kernels with a screening length depending on the local Wigner-Seitz radius, rs(r), suffer an error associated with a spurious long-range repulsion in van der Waals bounded systems, which deteriorates the binding energy curve as compared to RPA. We analyze the source of the error and propose to replace rs(r) by a global, average rs in the kernel. Exemplary studies with the Corradini, del Sole, Onida, and Palummo kernel show that while this change does not affect the already outstanding performance in crystalline solids, using an average rs significantly reduces the spurious long-range tail in the exchange-correlation kernel in van der Waals bounded systems. When this method is combined with further corrections using local dielectric response theory, the binding energy of the Kr dimer is improved three times as compared to RPA.

  12. Insights into the spurious long-range nature of local r-dependent non-local exchange-correlation kernels.

    PubMed

    Lu, Deyu

    2016-08-01

    A systematic route to go beyond the exact exchange plus random phase approximation (RPA) is to include a physical exchange-correlation kernel in the adiabatic-connection fluctuation-dissipation theorem. In the previous study [D. Lu, J. Chem. Phys. 140, 18A520 (2014)], we found that non-local kernels with a screening length depending on the local Wigner-Seitz radius, rs(r), suffer an error associated with a spurious long-range repulsion in van der Waals bounded systems, which deteriorates the binding energy curve as compared to RPA. We analyze the source of the error and propose to replace rs(r) by a global, average rs in the kernel. Exemplary studies with the Corradini, del Sole, Onida, and Palummo kernel show that while this change does not affect the already outstanding performance in crystalline solids, using an average rs significantly reduces the spurious long-range tail in the exchange-correlation kernel in van der Waals bounded systems. When this method is combined with further corrections using local dielectric response theory, the binding energy of the Kr dimer is improved three times as compared to RPA. PMID:27497553

  13. Radio-Observaciones del OH EN la Coma del Cometa Halley Desde EL Hemisferio Sur

    NASA Astrophysics Data System (ADS)

    Silva, A. M.; Bajaja, E.; Morras, R.; Cersosimo, J. C.; Martin, M. C.; Arnal, E. M.; Poppel, W. G. L.; Colomb, F. R.; Mazzaro, J.; Olalde, J. C.; Boriakoff, V.; Mirabel, I. F.

    1987-05-01

    Se utilizó una antena de 30 metros del Instituto Argentino de Radioastronomía para observaciones diarias Cf ebrero a abril de 1986) de la transición en 1667 MHz ( λ = 18 cm) del OH en la coma del cometa Halley. De las observaciones realizadas se concluye: 1) El número promedio de moléculas de OH en la coma durante 37 días de observación fue de (8.9±3.5)x1034 moléculas, lo que implica una tasa de producción promedio de OH de 1.8x1029 moléculas seg-1 y consecuentemente una pérdida de masa promedio de 17±6 toneladas seg-1 . Este valor está de acuerdo con las mediciones realizadas por las sondas Vega y Giotto. 2) El monitoreo desde el lAR revela la existencia de variaciones bruscas en los flujos de absorción del OH. Estas variaciones son consistentes con los modelos que representan la producción gaseosa a partir de ejecciones y/o desprendimientos discretos de materia congelada del núcleo. 3) Las variaciones en la densidad de flujo son consistentes con las estimaciones de los tiem- pos de vida medios del H2O y del OH en presencia del campo de radiación solar. 4) Se encuentra una correlación entre la intensidad del flujo absorbido y anisotropías en Ia dinamica de la coma.

  14. Visiting the Gödel universe.

    PubMed

    Grave, Frank; Buser, Michael

    2008-01-01

    Visualization of general relativity illustrates aspects of Einstein's insights into the curved nature of space and time to the expert as well as the layperson. One of the most interesting models which came up with Einstein's theory was developed by Kurt Gödel in 1949. The Gödel universe is a valid solution of Einstein's field equations, making it a possible physical description of our universe. It offers remarkable features like the existence of an optical horizon beyond which time travel is possible. Although we know that our universe is not a Gödel universe, it is interesting to visualize physical aspects of a world model resulting from a theory which is highly confirmed in scientific history. Standard techniques to adopt an egocentric point of view in a relativistic world model have shortcomings with respect to the time needed to render an image as well as difficulties in applying a direct illumination model. In this paper we want to face both issues to reduce the gap between common visualization standards and relativistic visualization. We will introduce two techniques to speed up recalculation of images by means of preprocessing and lookup tables and to increase image quality through a special optimization applicable to the Gödel universe. The first technique allows the physicist to understand the different effects of general relativity faster and better by generating images from existing datasets interactively. By using the intrinsic symmetries of Gödel's spacetime which are expressed by the Killing vector field, we are able to reduce the necessary calculations to simple cases using the second technique. This even makes it feasible to account for a direct illumination model during the rendering process. Although the presented methods are applied to Gödel's universe, they can also be extended to other manifolds, for example light propagation in moving dielectric media. Therefore, other areas of research can benefit from these generic improvements. PMID

  15. Boundary Preserving Dense Local Regions.

    PubMed

    Kim, Jaechul; Grauman, Kristen

    2015-05-01

    We propose a dense local region detector to extract features suitable for image matching and object recognition tasks. Whereas traditional local interest operators rely on repeatable structures that often cross object boundaries (e.g., corners, scale-space blobs), our sampling strategy is driven by segmentation, and thus preserves object boundaries and shape. At the same time, whereas existing region-based representations are sensitive to segmentation parameters and object deformations, our novel approach to robustly sample dense sites and determine their connectivity offers better repeatability. In extensive experiments, we find that the proposed region detector provides significantly better repeatability and localization accuracy for object matching compared to an array of existing feature detectors. In addition, we show our regions lead to excellent results on two benchmark tasks that require good feature matching: weakly supervised foreground discovery and nearest neighbor-based object recognition. PMID:26353319

  16. Sound localization in the alligator.

    PubMed

    Bierman, Hilary S; Carr, Catherine E

    2015-11-01

    In early tetrapods, it is assumed that the tympana were acoustically coupled through the pharynx and therefore inherently directional, acting as pressure difference receivers. The later closure of the middle ear cavity in turtles, archosaurs, and mammals is a derived condition, and would have changed the ear by decoupling the tympana. Isolation of the middle ears would then have led to selection for structural and neural strategies to compute sound source localization in both archosaurs and mammalian ancestors. In the archosaurs (birds and crocodilians) the presence of air spaces in the skull provided connections between the ears that have been exploited to improve directional hearing, while neural circuits mediating sound localization are well developed. In this review, we will focus primarily on directional hearing in crocodilians, where vocalization and sound localization are thought to be ecologically important, and indicate important issues still awaiting resolution. PMID:26048335

  17. Local non-equilibrium thermodynamics

    PubMed Central

    Jinwoo, Lee; Tanaka, Hajime

    2015-01-01

    Local Shannon entropy lies at the heart of modern thermodynamics, with much discussion of trajectory-dependent entropy production. When taken at both boundaries of a process in phase space, it reproduces the second law of thermodynamics over a finite time interval for small scale systems. However, given that entropy is an ensemble property, it has never been clear how one can assign such a quantity locally. Given such a fundamental omission in our knowledge, we construct a new ensemble composed of trajectories reaching an individual microstate, and show that locally defined entropy, information, and free energy are properties of the ensemble, or trajectory-independent true thermodynamic potentials. We find that the Boltzmann-Gibbs distribution and Landauer's principle can be generalized naturally as properties of the ensemble, and that trajectory-free state functions of the ensemble govern the exact mechanism of non-equilibrium relaxation. PMID:25592077

  18. Local non-equilibrium thermodynamics.

    PubMed

    Jinwoo, Lee; Tanaka, Hajime

    2015-01-01

    Local Shannon entropy lies at the heart of modern thermodynamics, with much discussion of trajectory-dependent entropy production. When taken at both boundaries of a process in phase space, it reproduces the second law of thermodynamics over a finite time interval for small scale systems. However, given that entropy is an ensemble property, it has never been clear how one can assign such a quantity locally. Given such a fundamental omission in our knowledge, we construct a new ensemble composed of trajectories reaching an individual microstate, and show that locally defined entropy, information, and free energy are properties of the ensemble, or trajectory-independent true thermodynamic potentials. We find that the Boltzmann-Gibbs distribution and Landauer's principle can be generalized naturally as properties of the ensemble, and that trajectory-free state functions of the ensemble govern the exact mechanism of non-equilibrium relaxation. PMID:25592077

  19. Locally-referenced ultrasonic--LPS for localization and navigation.

    PubMed

    Gualda, David; Ureña, Jesús; García, Juan C; Lindo, Alejandro

    2014-01-01

    This paper presents a flexible deployment of ultrasonic position sensors and a novel positioning algorithm suitable for the navigation of mobile robots (MRs) in extensive indoor environments. Our proposal uses several independently-referenced local positioning systems (LPS), which means that each one of them operates within its own local reference system. In a typical layout, an indoor extensive area can be covered using just a reduced set of globally-referenced LPS (GRLPS), whose beacon positions are known to the global reference system, while the rest of the space can be covered using locally-referenced LPSs (LRLPS) that can be distributed arbitrarily. The number of LRLPS and their position can be also changed at any moment. The algorithm is composed of several Bayesian filters running in parallel, so that when an MR is under the GRLPS coverage area, its position is updated by a global filter, whereas when the MR is inside the LRLPS area, its position is updated using position increments within a local filter. The navigation algorithm has been tested by simulation and with actual data obtained using a real set of ultrasonic LPSs. PMID:25412215

  20. Locally-Referenced Ultrasonic – LPS for Localization and Navigation

    PubMed Central

    Gualda, David; Ureña, Jesús; García, Juan C.; Lindo, Alejandro

    2014-01-01

    This paper presents a flexible deployment of ultrasonic position sensors and a novel positioning algorithm suitable for the navigation of mobile robots (MRs) in extensive indoor environments. Our proposal uses several independently-referenced local positioning systems (LPS), which means that each one of them operates within its own local reference system. In a typical layout, an indoor extensive area can be covered using just a reduced set of globally-referenced LPS (GRLPS), whose beacon positions are known to the global reference system, while the rest of the space can be covered using locally-referenced LPSs (LRLPS) that can be distributed arbitrarily. The number of LRLPS and their position can be also changed at any moment. The algorithm is composed of several Bayesian filters running in parallel, so that when an MR is under the GRLPS coverage area, its position is updated by a global filter, whereas when the MR is inside the LRLPS area, its position is updated using position increments within a local filter. The navigation algorithm has been tested by simulation and with actual data obtained using a real set of ultrasonic LPSs. PMID:25412215

  1. Determinacion de periodos fundamentales del suelo mediante vibraciones ambientales en el municipio de Humacao, Puerto Rico

    NASA Astrophysics Data System (ADS)

    Cintron Aponte, Rommel

    La tecnica de Nakamura ha sido utilizada a nivel mundial para determinar periodos fundamentales del suelo. La tecnica consiste en calcular y graficar cocientes espectrales H/V de vibraciones ambientales registradas sobre el suelo. Mediciones de vibraciones ambientales fueron tomadas en 151 lugares dentro del municipio de Humacao, localizado al este de Puerto Rico. Los datos se procesaron utilizando espectros de Fourier y espectros de potencia. La tecnica fue validada al compararla con los resultados de cocientes espectrales H/V de registros de sismos debiles y tambien con una modelacion numerica realizada con datos de un ensayo "downhole". Las graficas de los cocientes espectrales H/V fueron divididas en casos y grupos, los cuales dependen de la facilidad para identificar el periodo fundamental pico y amplitudes en frecuencias menores de 1 Hz, respectivamente. Los resultados obtenidos con ambos espectros fueron comparados y se concluye que los mismos se complementan para proveer resultados mas confiables. Se crearon mapas de periodos fundamentales, factores de amplitud, isoperiodos y clasificacion sismica de sitio. Los mapas de isoperiodos fueron realizados en las zonas mas pobladas sobre depositos de suelo. El mapa de periodos fundamentales del suelo mostro buena correlacion con la geologia local. El mapa de clasificacion sismica derivado de periodos de sitio fue comparado con el mapa de clasificacion sismica derivado de barrenos geotecnicos. El mapa de clasificacion obtenido de periodos puede sobreestimar un poco algunas clasificaciones del suelo. Sin embargo, este mapa puede proveer un estimado aproximado de la velocidad de onda de corte promedio del suelo hasta una profundidad de 100 pies (30 metros).

  2. Toric K3-fibred Calabi-Yau manifolds with del Pezzo divisors for string compactifications

    NASA Astrophysics Data System (ADS)

    Cicoli, Michele; Kreuzer, Maximilian; Mayrhofer, Christoph

    2012-02-01

    We analyse several explicit toric examples of compact K3-fibred Calabi-Yau three-folds. These manifolds can be used for the study of string dualities and are crucial ingredients for the construction of LARGE Volume type IIB vacua with promising applications to cosmology and particle phenomenology. In order to build a phenomenologically viable model, on top of the two moduli corresponding to the base and the K3 fibre, we demand also the existence of two additional rigid divisors: the first supporting the non-perturbative effects needed to achieve moduli stabilisation, and the second allowing the presence of chiral matter on wrapped D-branes. We clarify the topology of these rigid divisors by discussing the interplay between a diagonal structure of the Calabi-Yau volume and D-terms. Del Pezzo divisors appearing in the volume form in a completely diagonal way are natural candidates for supporting non-perturbative effects and for quiver constructions, while `non-diagonal' del Pezzo and rigid but not del Pezzo divisors are particularly interesting for model building in the geometric regime. Searching through the existing list of four dimensional reflexive lattice polytopes, we find 158 examples admitting a Calabi-Yau hypersurface with a K3 fibration and four Kähler moduli where at least one of the toric divisors is a `diagonal' del Pezzo. We work out explicitly the topological details of a few examples showing how, in the case of simplicial polytopes, all the del Pezzo divisors are `diagonal', while `non-diagonal' ones appear only in the case of non-simplicial polytopes. A companion paper will use these results in the study of moduli stabilisation for globally consistent explicit Calabi-Yau compactifications with the local presence of chirality.

  3. Foreign English Language Teachers' Local Pedagogy

    ERIC Educational Resources Information Center

    Eusafzai, Hamid Ali Khan

    2015-01-01

    ELT methods have been criticized for being limited and inadequate. Postmethod pedagogy has been offered as an alternate to these methods. The postmethod pedagogy emphasises localization of pedagogy and celebrates local culture, teachers and knowledge. Localizing pedagogy is easy for local teachers as knowledge and understanding of the local comes…

  4. Restoring San Xavier del Bac, "Our Church": Tohono O'odham Work to Restore the 200-Year-Old Church Built by Their Ancestors.

    ERIC Educational Resources Information Center

    Fontana, Bernard L.

    1995-01-01

    The Tohono O'odham built Mission San Xavier del Bac for Franciscan missionaries in the late 1700s and have protected and cared for it through changing circumstances ever since. As part of a massive restoration project, outstanding experts have been restoring the church's painted and sculpted interior and training local Tohono O'odham to be…

  5. Pressure ulcers. Local wound care.

    PubMed

    Goode, P S; Thomas, D R

    1997-08-01

    Local care of pressure ulcers includes wound cleansing, débridement, and dressings. Wound cleansing should remove loose debris and exudate but should not damage viable tissue. Saline irrigation is the standard. Débridement is often necessary for Stage III and IV pressure ulcers and can be performed autolytically, mechanically, enzymatically, or sharply. Prompt débridement is essential for infected wounds. Dressings should keep the wound bed continuously moist, should not be toxic to granulation tissue, and should keep the surrounding intact skin dry. Randomized, controlled clinical trials are necessary to define optimal local wound care further. PMID:9227943

  6. Multigrid for locally refined meshes

    SciTech Connect

    Shapira, Y.

    1999-12-01

    A multilevel method for the solution of finite element schemes on locally refined meshes is introduced. For isotropic diffusion problems, the condition number of the two-level method is bounded independently of the mesh size and the discontinuities in the diffusion coefficient. The curves of discontinuity need not be aligned with the coarse mesh. Indeed, numerical applications with 10 levels of local refinement yield a rapid convergence of the corresponding 10-level, multigrid V-cycle and other multigrid cycles which are more suitable for parallelism even when the discontinuities are invisible on most of the coarse meshes.

  7. The Louisiana Go Local Experience

    PubMed Central

    Fahrmann, Melissa; Pesch, Wendy T.

    2012-01-01

    Between 2006 and 2009, two health sciences librarians at Baton Rouge General Medical Center created and launched the Louisiana segment of the National Library of Medicine’s Go Local program, whose ultimate goal was to improve the health information-seeking experience of the general public. Louisiana Go Local was successfully launched in October 2009, but in spring 2010, the national umbrella project was cancelled by the National Library of Medicine. This article describes the three-year development of a statewide database of health services descriptions and contact information to assist non-expert health information seekers in finding those health care providers located geographically closest to them. PMID:22347810

  8. Operator Localization of Virtual Objects

    NASA Technical Reports Server (NTRS)

    Ellis, Stephen R.; Menges, Brian M.; Null, Cynthia H. (Technical Monitor)

    1998-01-01

    Errors in the localization of nearby virtual objects presented via see-through, helmet mounted displays are examined as a function of viewing conditions and scene content. Monocular, biocular or stereoscopic presentation of the virtual objects, accommodation (required focus), subjects'age, and the position of physical surfaces are examined. Nearby physical surfaces are found to introduce localization errors that differ depending upon the other experimental factors. The apparent physical size and transparency of the virtual objects and physical surfaces respectively are also influenced by their relative position when superimposed. Design implications are discussed.

  9. A local adaptive image descriptor

    NASA Astrophysics Data System (ADS)

    Zahid Ishraque, S. M.; Shoyaib, Mohammad; Abdullah-Al-Wadud, M.; Monirul Hoque, Md; Chae, Oksam

    2013-12-01

    The local binary pattern (LBP) is a robust but computationally simple approach in texture analysis. However, LBP performs poorly in the presence of noise and large illumination variation. Thus, a local adaptive image descriptor termed as LAID is introduced in this proposal. It is a ternary pattern and is able to generate persistent codes to represent microtextures in a given image, especially in noisy conditions. It can also generate stable texture codes if the pixel intensities change abruptly due to the illumination changes. Experimental results also show the superiority of the proposed method over other state-of-the-art methods.

  10. Localized lesions in secondary syphilis.

    PubMed

    Dar, Nasser Rashid; Raza, Naeem

    2008-05-01

    The clinical manifestations of secondary syphilis are variable and can mimic many skin diseases, mostly being generalized and symmetrical in distribution. Localized lesions of secondary syphilis are rarely seen in dermatology clinics. We report an unusual presentation wherein a patient had localized lesions over face and soles only. There is a need for increased awareness on the part of physicians to recognize new patterns of syphilitic infection, together with a willingness to consider the diagnosis of syphilis in patients with unusual clinical features. PMID:18541087

  11. Assessing Glacier Hazards At Ghiacciaio Del Belvedere, Macugnaga, Italian Alps

    NASA Astrophysics Data System (ADS)

    Haeberli, W.; Chiarle, M.; Mortara, G.; Mazza, A.

    The uppermost section of the Valle Anzasca behind and above the community of Macugnaga in the Italian Alps is one of the most spectacular high-mountain land- scapes in Europe, with gigantic rock walls and numerous steep hanging glaciers. Its main glacier, Ghiacciaio del Belvedere at the foot of the huge Monte Rosa east face, is a heavily debris-covered glacier flowing on a thick sediment bed. Problems with floods, avalanches and debris flows from this ice body have been known for extended time periods. Most recently, however, the evolution of this highly dynamic environ- ment has become more dramatic. An outburst of Lago delle Locce, an ice-dammed lake at the confluenec of the tributary Ghiacciaio delle Locce with Ghiacciaio del Belvedere, caused heavy damage in 1979 and necessitated site investigation and con- struction work to be done for flood protection. The intermittent glacier growth ten- dency in the 1970es induced strong bulging of the glacier surface and, in places, caused the glacier tongue to override historical morains and to destroy newly-grown forest stands. A surge-type flow acceleration started in the lower parts of the Monte- Rosa east face during summer 2000, leading to strong crevassing and deformation of Ghiacciaio del Belvedere and extreme bulging of its orographic right margin. High water pressure and accelerated movement lasted into winter 2001/2002: the ice now started overriding the LIA moraine near Rifugio Zamboni of the CAI. In addition but rather independently, a most active detachment zone for rock falls and debris flows developed for several years now in the east face of Monte Rosa, somewhat more to the south of the accelerated glacier movement and at an altitude where relatively warm permafrost must be expected. Besides the scientific interest in these phenomena, the growing hazard potential to the local infrastructure must be considered seriously. Es- pecially potentials for the destabilization of large rock and ice masses in the

  12. Vigilando la Calidad del Agua de los Grandes Rios de la Nacion: El Programa NASQAN del Rio Grande (Rio Bravo del Norte)

    USGS Publications Warehouse

    Lurry, Dee L.; Reutter, David C.; Wells, Frank C.; Rivera, M.C., (translator); Munoz, A.

    1998-01-01

    La Oficina del Estudio Geologico de los Estados Unidos (U.S. Geological Survey, 0 USGS) ha monitoreado la calidad del agua de la cuenca del Rio Grande (Rio Bravo del Norte) desde 1995 como parte de la rediseiiada Red Nacional para Contabilizar la Calidad del Agua de los Rios (National Stream Quality Accounting Network, o NASOAN) (Hooper and others, 1997). EI programa NASOAN fue diseiiado para caracterizar las concentraciones y el transporte de sedimento y constituyentes quimicos seleccionados, encontrados en los grandes rios de los Estados Unidos - incluyendo el Misisipi, el Colorado y el Columbia, ademas del Rio Grande. En estas cuatro cuencas, el USGS opera actualmente (1998) una red de 40 puntos de muestreo pertenecientes a NASOAN, con un enfasis en cuantificar el flujo en masa (la cantidad de material que pasa por la estacion, expresado en toneladas por dial para cada constituyente. Aplicacando un enfoque consistente, basado en la cuantificacion de flujos en la cuenca del Rio Grande, el programa NASOAN esta generando la informacion necesaria para identificar fuentes regionales de diversos contaminantes, incluyendo sustancias qui micas agricolas y trazas elementos en la cuenca. EI efecto de las grandes reservas en el Rio Grande se puede observar segun los flujos de constituyentes discurren a 10 largo del rio. EI analisis de los flujos de constituyentes a escala de la cuenca proveera los medios para evaluar la influencia de la actividad humana sobre las condiciones de calidad del agua del Rio Grande.

  13. Superbubbles and Local Cosmic Rays

    NASA Technical Reports Server (NTRS)

    Streitmatter, Robert E.; Jones, Frank C.

    2005-01-01

    We consider the possibility that distinctive features of the local cosmic ray spectra and composition are influenced by the Solar system being embedded within the cavity of an ancient superbubble. Shifts in the measured cosmic ray composition between 10(exp 11) and 10(exp 20) eV as well as the "knee" and "second knee" may be understood in this picture.

  14. Arthur Smith, Local Baptist Pastor.

    ERIC Educational Resources Information Center

    Heaton, Moss, Ed.

    1985-01-01

    Written and published by the students at Gary High School this volume has three articles dealing with East Texas life. The first "Arthur Smith" (David Hancock and others) is an account of growing up in Marian County, Texas is described by the local Baptist minister. The pastor begins with the year of his birth and gives detailed information about…

  15. Local Area Networks: Part II.

    ERIC Educational Resources Information Center

    Dessy, Raymond E., Ed.

    1982-01-01

    Discusses five approaches used by industry/colleges to provide local area network (LAN) capabilities in the analytical laboratory: (1) mixed baseband bus network coupled to a star net; (2) broadband bus network; (3) ring network; (4) star network coupled to broadband net; and (5) simple multiprocessor center. Part I (September issue) focused on…

  16. Local Area Networks: Part I.

    ERIC Educational Resources Information Center

    Dessy, Raymond E.

    1982-01-01

    Local area networks are common communication conduits allowing various terminals, computers, discs, printers, and other electronic devices to intercommunicate over short distances. Discusses the vocabulary of such networks including RS-232C point-to-point and IEEE-488 multidrop protocols; error detection; message packets; multiplexing; star, ring,…

  17. Local Evaluation of Chemistry Journals

    ERIC Educational Resources Information Center

    Kraus, Joseph R.; Hansen, Rachel

    2008-01-01

    This paper reports on the evaluation of local usage statistics of a specific set of chemistry journals at the University of Denver in Colorado, USA. The objective of the study is to demonstrate that commercial publishers in chemistry charge considerably more for their journals than those from the non-commercial sector. There are three variables…

  18. Local Control of Blood Flow

    ERIC Educational Resources Information Center

    Clifford, Philip S.

    2011-01-01

    Organ blood flow is determined by perfusion pressure and vasomotor tone in the resistance vessels of the organ. Local factors that regulate vasomotor tone include myogenic and metabolic autoregulation, flow-mediated and conducted responses, and vasoactive substances released from red blood cells. The relative importance of each of these factors…

  19. Community Education and Local Government

    ERIC Educational Resources Information Center

    Gamm, Larry; Wager, Sandra

    1975-01-01

    Describes development and preliminary implementation of the Community Education Program on Home Rule, a statewide program to aid local communities in educating citizens about the possibility of modifying their municipal government under the provisions of Pennsylvania's Home Rule Charter and Optional Plans Law. (JG)

  20. Research for Locally Relevant Solutions

    ERIC Educational Resources Information Center

    Association of Universities and Colleges of Canada, 2004

    2004-01-01

    In the CIDA-funded University Partnerships in Cooperation and Development program--where Canadian universities establish knowledge partnerships with Southern universities--projects with a well-developed research dimension have proven to be the strongest projects, with broader and deeper contributions to the local institutions and larger community.…

  1. Quantum Strategies and Local Operations

    NASA Astrophysics Data System (ADS)

    Gutoski, Gus

    2010-02-01

    This thesis is divided into two parts. In Part I we introduce a new formalism for quantum strategies, which specify the actions of one party in any multi-party interaction involving the exchange of multiple quantum messages among the parties. This formalism associates with each strategy a single positive semidefinite operator acting only upon the tensor product of the input and output message spaces for the strategy. We establish three fundamental properties of this new representation for quantum strategies and we list several applications, including a quantum version of von Neumann's celebrated 1928 Min-Max Theorem for zero-sum games and an efficient algorithm for computing the value of such a game. In Part II we establish several properties of a class of quantum operations that can be implemented locally with shared quantum entanglement or classical randomness. In particular, we establish the existence of a ball of local operations with shared randomness lying within the space spanned by the no-signaling operations and centred at the completely noisy channel. The existence of this ball is employed to prove that the weak membership problem for local operations with shared entanglement is strongly NP-hard. We also provide characterizations of local operations in terms of linear functionals that are positive and "completely" positive on a certain cone of Hermitian operators, under a natural notion of complete positivity appropriate to that cone. We end the thesis with a discussion of the properties of no-signaling quantum operations.

  2. Philippine Programme Initiates Local Empowerment.

    ERIC Educational Resources Information Center

    Malone, Mary

    1995-01-01

    Describes a public health program for mothers and children developed by UNICEF workers in the Philippines that incorporates literacy and environmental awareness along with the usual focus on immunizations, nutrition, and clean water. The program contained an organic gardening project intended to empower women at the local level. (LZ)

  3. Mesotherapy for local fat reduction.

    PubMed

    Jayasinghe, S; Guillot, T; Bissoon, L; Greenway, F

    2013-10-01

    Mesotherapy, which is the injection of substances locally into mesodermally derived subcutaneous tissue, developed from empirical observations of a French physician in the 1950s. Although popular in Europe for many medical purposes, it is used for local cosmetic fat reduction in the United States. This paper reviews manuscripts indexed in PubMed/MEDLINE under 'mesotherapy', which pertains to local fat reduction. The history of lipolytic mesotherapy, the physiology of body fat distribution, the mechanism of action of different lipolytic stimulators and their increased efficacy in combination are reviewed. Mesotherapy falls into two categories. Lipolytic mesotherapy using lipolytic stimulators requires more frequent treatments as the fat cells are not destroyed and can refill over time. Ablative mesotherapy destroys fat cells with a detergent, causes inflammation and scarring from the fat necrosis, but requires fewer treatments. The historic and empiric mixing of sodium channel blocking local anaesthetics in mesotherapy solutions inhibits the intended lipolysis. Major mesotherapy safety concerns include injection site infections from poor sterile technique. Cosmetic mesotherapy directs the area from which fat is lost to improve self-image. Studies were of relatively small number, many with limited sample sizes. Future research should be directed towards achieving a Food and Drug Administration indication rather than continuing expansion of off-label use. PMID:23800269

  4. Universities: Engaging with Local Communities

    ERIC Educational Resources Information Center

    Universities UK, 2010

    2010-01-01

    This leaflet illustrates the many ways in which universities impact on the local area. Universities are a major contributor to the economy in their own right, both as employers and purchasers of goods. Their social and cultural influence is also felt through their provision of: (1) art galleries, museums and exhibitions; (2) cinemas and theatres;…

  5. State and Local Revenue Potential.

    ERIC Educational Resources Information Center

    Quindry, Kenneth E.

    This report contains the results of an extensive study into State and local tax revenue potentials for the 15 Southern Regional Education Board (SREB) States. It identifies both the degree of current use and the potential for increased use of (1) general and selective sales and gross receipts taxes, (2) death and gift taxes, (3) property taxes,…

  6. Local shape of pictorial relief

    PubMed Central

    Koenderink, Jan; van Doorn, Andrea; Wagemans, Johan

    2014-01-01

    How is pictorial relief represented in visual awareness? Certainly not as a “depth map,” but perhaps as a map of local surface attitudes (Koenderink & van Doorn, 1995). Here we consider the possibility that observers might instead, or concurrently, represent local surface shape, a geometrical invariant with respect to motions. Observers judge local surface shape, in a picture of a piece of sculpture, on a five-point categorical scale. Categories are cap–ridge–saddle–rut–cup–flat, where “flat” denotes the absence of shape. We find that observers readily perform such a task, with full resolution of a shape index scale (cap–ridge–saddle–rut–cup), and with excellent self-consistency over days. There exist remarkable inter-observer differences. Over a group of 10 naive observers we find that the dispersion of judgments peaks at the saddle category. There may be a relation of this finding to the history of the topic—Alberti's (1827) omission of the saddle category in his purportedly exhaustive catalog of local surface shapes. PMID:25469225

  7. Think Globally and Act Locally.

    ERIC Educational Resources Information Center

    Alger, Chadwick F.

    1985-01-01

    Suggests ways teachers can involve themselves and their students in local action as a means of furthering effective and practical global education. Considers possible barriers related to the ideology of the state system, and current breakthroughs, e.g., the nuclear freeze movement, anti-apartheid activism, and the sanctuary movement for Salvadoran…

  8. Targeting p21 Degradation Locally

    PubMed Central

    Xiong, Yue

    2016-01-01

    Just as the activity of many multifunctional proteins is restricted by subcellular localization, so is their regulation. In this issue of Development Cell, Starostina et al. identify an E3 ubiquitin ligase, CRL2LRR1, for the cyclin-dependent kinase inhibitor p21 that specifically ubiquitylates cytoplasmic p21 to facilitate cell migration. PMID:21074711

  9. Local Decisions and Global Networks

    ERIC Educational Resources Information Center

    King, David C.; Long, Cathryn J.

    1976-01-01

    Impact of economic and urban planning on the natural environment can be studied through local situations: California conservation students realized the detrimental effects of a seemingly beneficial dam project. Students were inspired to initiate community-state action to correct damage to wildlife, sanitation, and farming. (AV)

  10. Localization model for cochlear implants

    NASA Astrophysics Data System (ADS)

    Miller, Douglas A.; Matin, Mohammad A.

    2011-09-01

    Normal hearing persons are able to localize the direction of sounds better using both ears than when listening with only one ear. Localization ability is dependent on auditory system perception of interaural differences in time, intensity, and phase. Interaural timing differences (ITDs) provide information for locating direction of low and mid frequency sounds, while interaural level differences (ILDs), which occur because of the horizontal plane shadowing effect of the head, provide information for locating direction of higher frequency sounds. The head related transfer function (HRTF) contains characteristic information important for acoustic localization. Models based on HRTFs take into account head shadow, torso, and pinna effects, and their impact on interaural frequency, level, and timing differences. Cochlear implants (CIs) have proven a successful treatment for persons with bilateral severe to profound hearing loss. A problem is that only some ITD and ILD cues are maintained with CI sound processing, and the microphone position alters the acoustic cues. The relative impact of differences in physical cues received by the auditory system with bilateral CIs versus differences in the ability of the damaged auditory nervous system to process bilateral inputs is not yet clear. The model presented in this paper was constructed as a step toward answering this question, and is intended to serve as a tool for future development of more optimal signal processing algorithms that may provide better localization ability for persons with bilateral CIs.

  11. Collaboration with the Local Community.

    ERIC Educational Resources Information Center

    Jackson, Michael L.; Cherrey, Cynthia

    2002-01-01

    Colleges and universities continually search for ways to enhance the safety and security of their educational programs and physical plant. This article examines how the University of Southern California and other institutions are using collaborative efforts with the local community to enhance their mutual safety and security through dynamic…

  12. Local Violence and Educational Attainment.

    ERIC Educational Resources Information Center

    Grogger, Jeffrey

    1997-01-01

    High School and Beyond data were used to analyze how local violence affects high school graduation and college attendance. Moderate violence reduced the likelihood of graduation by 5.1 percentage points and college attendance by 6.9 points. More substantial violence raised the dropout rate by 27% and reduced college attendance by 15.9 points.…

  13. Sound localization by echolocating bats

    NASA Astrophysics Data System (ADS)

    Aytekin, Murat

    Echolocating bats emit ultrasonic vocalizations and listen to echoes reflected back from objects in the path of the sound beam to build a spatial representation of their surroundings. Important to understanding the representation of space through echolocation are detailed studies of the cues used for localization, the sonar emission patterns and how this information is assembled. This thesis includes three studies, one on the directional properties of the sonar receiver, one on the directional properties of the sonar transmitter, and a model that demonstrates the role of action in building a representation of auditory space. The general importance of this work to a broader understanding of spatial localization is discussed. Investigations of the directional properties of the sonar receiver reveal that interaural level difference and monaural spectral notch cues are both dependent on sound source azimuth and elevation. This redundancy allows flexibility that an echolocating bat may need when coping with complex computational demands for sound localization. Using a novel method to measure bat sonar emission patterns from freely behaving bats, I show that the sonar beam shape varies between vocalizations. Consequently, the auditory system of a bat may need to adapt its computations to accurately localize objects using changing acoustic inputs. Extra-auditory signals that carry information about pinna position and beam shape are required for auditory localization of sound sources. The auditory system must learn associations between extra-auditory signals and acoustic spatial cues. Furthermore, the auditory system must adapt to changes in acoustic input that occur with changes in pinna position and vocalization parameters. These demands on the nervous system suggest that sound localization is achieved through the interaction of behavioral control and acoustic inputs. A sensorimotor model demonstrates how an organism can learn space through auditory-motor contingencies

  14. A Mathematical Foundation for Locality

    NASA Astrophysics Data System (ADS)

    Bierhorst, Peter L.

    This work is motivated by two non-intuitive predictions of Quantum Mechanics:non-locality and contextuality . Non-locality is a phenomenon whereby interactions between spatially separated objects appear to be occurring faster than the speed of light. Contextuality is a phenomenon whereby the outcome of a measurement cannot be interpreted as the revelation of an intrinsic fixed property of the system being measured, but instead necessarily depends on the configuration of the measurement apparatus. Quantum Mechanics predicts non-local behavior in certain types of experiments collectively known as Bell tests. However, ruling out all possible alternative local theories is a subtle and demanding task. In this work, we lay out a mathematically-rigorous framework for analyzing Bell experiments. Using this framework, we derive the famous Clauser-Horne-Shimony-Holt (CHSH) inequality, an important constraint that is obeyed by all local theories and violated by Quantum Mechanics. We further demonstrate how to analyze the data of a CHSH experiment without assuming that successive experimental trials are independent and/or identically distributed. We also derive the Clauser-Horne (CH74) inequality, an inequality that is more well-suited for realistic Bell experiments using photons. We demonstrate a robust method for statistically analyzing the data of a CH74 experiment, and show how to calculate exact p-values for this analysis, improving on the previously-best-known (loose) upper bounds obtained from Hoeffding-style inequalities. The work concludes with an exploration of contextuality. The Kochen-Specker theorem -- a result demonstrating the contextual nature of Quantum Mechanics -- is applied to resolve a conjecture in Domain Theory regarding the spectral order on quantum states.

  15. Stacking attributes from local slopes

    NASA Astrophysics Data System (ADS)

    Ghosh, S.; Gajewski, D.; Dell, S.; Nath, S. K.; Wave Inversion Technology (Wit) Consortium

    2010-12-01

    CMP stacking is controlled by the stacking velocity which is determined by a one-dimendional optimization procedure using semblance as a coherence criterion. New multi-parameter stacking formulas like the Common Reflection Surface (CRS) operator consider neighboring CMP locations in the stack. These methods stack considerably more traces than conventional CMP processing leading to stacked sections with an improved signal-to-nose ratio and better image quality. The corresponding stacking trajectories are controlled by three stacking attributes for the 2-D case and eight for the 3-D case. The determination of these attributes requires a multi-dimensional optimization procedure which is time consuming. If we know good starting values, we can limit the search intervals considerably and speed up the process. It was shown that the stacking attributes are linked to local slopes in seismic zero offset and constant offset sections. Therefore, the determination of local slopes can guide the choice of the search intervals in the optimization procedure. We use structural tensors for the determination of local slopes. Structural tensors represent a versatile tool to investigate coherent features in the data superior to other slop determination tools like slant stacking or plane wave destructors. The window size is adjustable and allows to optimize smoothing and smearing in the slope determination process where the smoothing can be performed along structural events (directional smoothing). This smart feature helps to consider complex geologies and acknowledges faults and conflicting dips without any significant change in computation time. Different variants of the algorithm are used to determine slopes in CMP gathers, stacked and time or depth migrated sections. The results of the local slope determinations are used to compute stacking attributes for the CRS method. We compare these to stacking attributes obtained from optimization. The attributes determined from local slopes

  16. Educational and Demographic Profile: Del Norte County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Del Norte County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  17. Del Mod System. 1972 Annual Report.

    ERIC Educational Resources Information Center

    Purnell, Charlotte H.

    The overall aim of the Del Mod System is the improvement of science programs taught in Delaware schools; it is a working agreement among the University of Delaware, Delaware Technical and Community College, Delaware State College, State Department of Public Instruction, industry, and the schools. It was formed to bring about changes in science…

  18. Andrea del Sarto rehabilitated: a psychoanalytic emendation.

    PubMed

    Trosman, Harry

    2002-01-01

    Ernest Jones's "The Influence of Andrea del Sarto's Wife on His Art" (1913) is an early example of psychoanalysis applied to the study of a prominent painter. Greatly influenced by Freud's Leonardo da Vinci and a Memory of His Childhood, Jones gave excessive credence to Vasari's highly prejudicial account of the life of del Sarto, on which the study relied heavily. Jones attempted to account psychologically for the circumstance that del Sarto, though highly skilled and "faultless," was not the equal of the three preeminent masters of the Italian High Renaissance: Leonardo, Michelangelo, and Raphael. Jones's uncritical acceptance of the Vasari biography encouraged him to view Sarto's assumed deficiency as the result of excessive attachment to his wife, a pathological uxoriousness. A contemporary psychoanalytic perspective, with its emphasis on the emotive response of the analyst, requires us to pay attention to the evocative nature of the work of the artist, an approach Jones neglected. In an examination of several paintings, the artist's sensitivity to the position of the spectator is explored, as is the interest in involving the viewer spatially and emotionally. An appreciation for the viewer's position is consistent with a capacity for using projected internal objects for creative purposes. The presence of this capacity suggests a revised view of del Sarto's contribution to art and of his relationship with his wife. PMID:12580329

  19. Comments on localized and integral localized approximations in spherical coordinates

    NASA Astrophysics Data System (ADS)

    Gouesbet, Gérard; Lock, James A.

    2016-08-01

    Localized approximation procedures are efficient ways to evaluate beam shape coefficients of laser beams, and are particularly useful when other methods are ineffective or inefficient. Comments on these procedures are, however, required in order to help researchers make correct decisions concerning their use. This paper has the flavor of a short review and takes the opportunity to attract the attention of the readers to a required refinement of terminology.

  20. Sacroplasty for Local or Massive Localization of Multiple Myeloma

    SciTech Connect

    Basile, Antonio; Tsetis, Dimitrios; Cavalli, Maide; Fiumara, Paolo; Raimondo, Francesco Di; Coppolino, Francesco; Coppolino, Carmelo; Mundo, Elena; Desiderio, Carla; Granata, Antonio; Patti, Maria Teresa

    2010-12-15

    The purpose of this study was to assess the efficacy of cementoplasty in the treatment of sacral multiple myelomas. We retrospectively reviewed the records of eight patients (four women and four men; age range 47-68 years; mean age 57.8) who underwent cementoplasty for painful osteolytic localization of multiple myeloma between April 2007 and May 2009. The patients had difficulty walking because of increasing pain. Six patients had persistent pain despite other cementoplasties for vertebral and femoral localization, whereas two patients referred at the time of diagnosis had only sacral lesions. The clinical indication for treatment was (1) a pain intensity score {>=}5 on visual analogue scale (VAS) and (2) pain totally or partially refractory to analgesic treatment in patients with a life expectancy >3 months. Technical planning was based on computed tomography and/or magnetic resonance imaging. Six patients had previously undergone radiotherapy or chemotherapy and were receiving varying doses of analgesics, whereas sacroplasty represented the first treatment for two patients. Five patients had monolateral local involvement, and the other patients had massive involvement of the sacrum; Technical success was achieved in all cases. We had only one small and asymptomatic foraminal leak. All patients experienced improvement in symptoms after the procedure, as demonstrated by improved VAS scores and performance status (PS) and decreased analgesic dose constant during follow-up. In our experience, percutaneous stabilization can be used effectively and safely in patients with focal or extensive involvement of the sacrum by multiple myeloma.

  1. Fractal superconductivity near localization threshold

    SciTech Connect

    Feigel'man, M.V.; Ioffe, L.B.; Kravtsov, V.E.; Cuevas, E.

    2010-07-15

    We develop a semi-quantitative theory of electron pairing and resulting superconductivity in bulk 'poor conductors' in which Fermi energy E{sub F} is located in the region of localized states not so far from the Anderson mobility edge E{sub c}. We assume attractive interaction between electrons near the Fermi surface. We review the existing theories and experimental data and argue that a large class of disordered films is described by this model. Our theoretical analysis is based on analytical treatment of pairing correlations, described in the basis of the exact single-particle eigenstates of the 3D Anderson model, which we combine with numerical data on eigenfunction correlations. Fractal nature of critical wavefunction's correlations is shown to be crucial for the physics of these systems. We identify three distinct phases: 'critical' superconductive state formed at E{sub F} = E{sub c}, superconducting state with a strong pseudo-gap, realized due to pairing of weakly localized electrons and insulating state realized at E{sub F} still deeper inside a localized band. The 'critical' superconducting phase is characterized by the enhancement of the transition temperature with respect to BCS result, by the inhomogeneous spatial distribution of superconductive order parameter and local density of states. The major new feature of the pseudo-gapped state is the presence of two independent energy scales: superconducting gap {Delta}, that is due to many-body correlations and a new 'pseudo-gap' energy scale {Delta}{sub P} which characterizes typical binding energy of localized electron pairs and leads to the insulating behavior of the resistivity as a function of temperature above superconductive T{sub c}. Two gap nature of the pseudo-gapped superconductor is shown to lead to specific features seen in scanning tunneling spectroscopy and point-contact Andreev spectroscopy. We predict that pseudo-gapped superconducting state demonstrates anomalous behavior of the optical

  2. Clinical and laboratory update on the DEL variant.

    PubMed

    Nuchnoi, Pornlada; Thongbus, Jairak; Srisarin, Apapan; Kerdpin, Usanee; Prachayasittikul, Virapong

    2014-01-01

    Serological assays for the RhD blood group are based on detection of the RhD antigen on human red blood cells using a specific anti-D antibody. The weak expression of the RhD antigen in the DEL variant hinders the sensitivity of conventional serological assays. Evidence of anti-D immunization in patients with D-negativity who have received DEL-variant blood units has been reported in various populations. This observation has prompted the need for genetic epidemiological and clinical data on the DEL variant in the development of DEL molecular diagnostic testing. This review highlights the molecular features of the DEL variant, the clinical consequences of DEL-blood transfusion, and current approaches for detection of the DEL-variant for donor screening and transfusion. PMID:25316658

  3. Local optimization of neuron arbors.

    PubMed

    Cherniak, C

    1992-01-01

    How parsimoniously is brain wiring laid out, that is, how well does a neuron minimize costs of connections among its synapses? Neural optimization of dendritic and axonic arbors can be evaluated using a generalization of the Steiner tree concept from combinatorial network optimization theory. Local branch-junction geometry of neuronal connecting structures fits a volume minimization model well. In addition, volume of the arborizations at this neighborhood level is significantly more strongly minimized than their length, signal propagation speed, or surface area. The mechanism of this local volume optimization resembles those involved in formation of nonliving tree structures such as river junctions and electric-discharge patterns, and appears to govern initial nerve growth-cone behavior through vector-mechanical energy minimization. PMID:1586674

  4. Subcellular localization of pituitary enzymes

    NASA Technical Reports Server (NTRS)

    Smith, R. E.

    1970-01-01

    A cytochemical procedure is reported for identifying subcellular sites of enzymes hydrolyzing beta-naphthylamine substrates, and to study the sites of reaction product localization in cells of various tissues. Investigations using the substrate Leu 4-methoxy-8-naphthylamine, a capture with hexonium pararosaniline, and the final chelation of osmium have identified the hydrolyzing enzyme of rat liver cells; this enzyme localized on cell membranes with intense deposition in the areas of the parcanaliculi. The study of cells in the anterior pituitary of the rat showed the deposition of reaction product on cell membrane; and on the membranes of secretion granules contained within the cell. The deposition of reaction product on the cell membrane however showed no increase or decrease with changes in the physiological state of the gland and release of secretion granules from specific cells.

  5. Nanoparticles heat through light localization.

    PubMed

    Hogan, Nathaniel J; Urban, Alexander S; Ayala-Orozco, Ciceron; Pimpinelli, Alberto; Nordlander, Peter; Halas, Naomi J

    2014-08-13

    Aqueous solutions containing light-absorbing nanoparticles have recently been shown to produce steam at high efficiencies upon solar illumination, even when the temperature of the bulk fluid volume remains far below its boiling point. Here we show that this phenomenon is due to a collective effect mediated by multiple light scattering from the dispersed nanoparticles. Randomly positioned nanoparticles that both scatter and absorb light are able to concentrate light energy into mesoscale volumes near the illuminated surface of the liquid. The resulting light absorption creates intense localized heating and efficient vaporization of the surrounding liquid. Light trapping-induced localized heating provides the mechanism for low-temperature light-induced steam generation and is consistent with classical heat transfer. PMID:24960442

  6. Update on local allergic rhinitis.

    PubMed

    Altıntoprak, Niyazi; Kar, Murat; Bayar Muluk, Nuray; Oktemer, Tugba; Ipci, Kagan; Birdane, Leman; Aricigil, Mitat; Senturk, Mehmet; Bafaqeeh, Sameer Ali; Cingi, Cemal

    2016-08-01

    We here provide an update on the literature regarding local allergic rhinitis (LAR). In reviewing LAR, we have included an updated definition, classifications, mechanisms, comorbidities, and recommendations for diagnosis and treatment for LAR, as well as the defined research areas for future evidence-based studies. LAR is a localised nasal allergic response in the absence of systemic atopy characterised by local production of specific IgE (sIgE) antibodies, a TH2 pattern of mucosal cell infiltration during natural exposure to aeroallergens, and a positive nasal allergen provocation test response, with the release of inflammatory mediators. The localised allergic response of LAR is an important topic for the study of allergies. This review provides an update on the current knowledge of LAR. PMID:27368453

  7. Acoustic Localization with Infrasonic Signals

    NASA Astrophysics Data System (ADS)

    Threatt, Arnesha; Elbing, Brian

    2015-11-01

    Numerous geophysical and anthropogenic events emit infrasonic frequencies (<20 Hz), including volcanoes, hurricanes, wind turbines and tornadoes. These sounds, which cannot be heard by the human ear, can be detected from large distances (in excess of 100 miles) due to low frequency acoustic signals having a very low decay rate in the atmosphere. Thus infrasound could be used for long-range, passive monitoring and detection of these events. An array of microphones separated by known distances can be used to locate a given source, which is known as acoustic localization. However, acoustic localization with infrasound is particularly challenging due to contamination from other signals, sensitivity to wind noise and producing a trusted source for system development. The objective of the current work is to create an infrasonic source using a propane torch wand or a subwoofer and locate the source using multiple infrasonic microphones. This presentation will present preliminary results from various microphone configurations used to locate the source.

  8. Coordinating sensing and local navigation

    NASA Astrophysics Data System (ADS)

    Slack, Marc G.

    1991-07-01

    Based on Navigation Templates (or NaTs), this work presents a new paradigm for local navigation which addresses the noisy and uncertain nature of sensor data. Rather than creating a new navigation plan each time the robot's perception of the world changes, the technique incorporates perceptual changes directly into the existing navigation plan. In this way, the robot's navigation plan is quickly and continuously modified, resulting in actions that remain coordinated with its changing perception of the world.

  9. Localized Pancreatic Cancer: Multidisciplinary Management.

    PubMed

    Coveler, Andrew L; Herman, Joseph M; Simeone, Diane M; Chiorean, E Gabriela

    2016-01-01

    Pancreatic cancer is an aggressive cancer that continues to have single-digit 5-year mortality rates despite advancements in the field. Surgery remains the only curative treatment; however, most patients present with late-stage disease deemed unresectable, either due to extensive local vascular involvement or the presence of distant metastasis. Resection guidelines that include a borderline resectable group, as well as advancements in neoadjuvant chemotherapy and radiation that improve resectability of locally advanced disease, may improve outcomes for patients with more invasive disease. Multi-agent chemotherapy regimens fluorouracil, leucovorin, irinotecan, and oxaliplatin (FOLFIRINOX) and nab-paclitaxel with gemcitabine improved response rates and survival in metastatic pancreatic cancer and are now being used in earlier stages for patients with localized potentially resectable and unresectable disease, with goals of downstaging tumors to allow margin-negative resection and reducing systemic recurrence. Chemoradiotherapy, although still controversial for both resectable and unresectable pancreatic cancer, is being used in the context of contemporary chemotherapy backbone regimens, and novel radiation techniques such as stereotactic body frame radiation therapy (SBRT) are studied on the premise of maintaining or improving efficacy and reducing treatment duration. Patient selection for optimal treatment designation is currently provided by multidisciplinary tumor boards, but biomarker discovery, in blood, tumors, or through novel imaging, is an area of intense research. Results to date suggest that some patients with unresectable disease at the outset have survival rates as good as those with initially resectable disease if able to undergo surgical resection. Long-term follow-up and improved clinical trials options are needed to determine optimal treatment modalities for patients with localized pancreatic cancer. PMID:27249726

  10. Local cloning of entangled qubits

    SciTech Connect

    Choudhary, Sujit K.; Kunkri, Samir; Rahaman, Ramij; Roy, Anirban

    2007-11-15

    We discuss the exact cloning of orthogonal but entangled qubits under local operations and classical communication. The amount of entanglement necessary in a blank copy is obtained for various cases. Surprisingly, this amount is more than 1 ebit for certain sets of two nonmaximal but equally entangled states of two qubits. To clone any three Bell states, at least log{sub 2} 3 ebit is necessary.

  11. Localization in optics - Quasiperiodic media

    NASA Astrophysics Data System (ADS)

    Kohmoto, Mahito; Sutherland, Bill; Iguchi, K.

    1987-06-01

    An experiment to probe the (quasi)localization of the photon is proposed, in which optical layers are constructed following the Fibonacci sequence. The transmission coefficient has a rich structure as a function of the wavelength of light and, in fact, is multifractal. For particular wavelengths for which the resonance conditions is satisfied, the light propagation has scaling with respect to the number of layers, as well as an interesting fluctuation.

  12. Coordinating sensing and local navigation

    NASA Technical Reports Server (NTRS)

    Slack, Marc G.

    1991-01-01

    Based on Navigation Templates (or NaTs), this work presents a new paradigm for local navigation which addresses the noisy and uncertain nature of sensor data. Rather than creating a new navigation plan each time the robot's perception of the world changes, the technique incorporates perceptual changes directly into the existing navigation plan. In this way, the robot's navigation plan is quickly and continuously modified, resulting in actions that remain coordinated with its changing perception of the world.

  13. Working within local funding trends.

    PubMed

    Pomales-Connors, Irma

    2004-06-01

    Like politics, environmentalism, and fashion, there are trends in health care research and funding. According to a series of reports by the Foundation Center-which collects, organizes, and communicates information on U.S. philanthropy-it is important to understand the significant financial and programmatic changes in the way foundations give. For pharmacists considering soliciting grant support, it is critical that they become aware of these trends and be responsive to the local or regional environments that affect funding. PMID:16553471

  14. Local public health system partnerships.

    PubMed Central

    Zahner, Susan J.

    2005-01-01

    OBJECTIVES: Interorganizational collaboration aimed at community health improvement is an expectation of local public health systems. This study assessed the extent to which such collaboration occurred within one state (Wisconsin), described the characteristics of existing partnerships, and identified factors associated with partnership effectiveness. METHODS: In Stage 1, local health department (LHD) directors in Wisconsin were surveyed (93% response rate). In Stage 2, LHDs completed self-administered mailed surveys for each partnership identified in Stage 1 (85% response rate). Two-level hierarchical logit regression methods were used to model relationships between partnership and LHD variables and partnership outcomes. Data from 924 partnerships associated with 74 LHDs were included in the analysis. RESULTS: Partnerships most frequently addressed tobacco prevention and control, maternal and child health, emergency planning, community assessment and planning, and immunizations. Partnering was most frequent with other government agencies, hospitals, medical practices or clinics, community-based organizations, and schools. Partnership effectiveness was predicted by having a budget, having more partners contributing financially, having a broader array of organizations involved, and having been in existence for a longer period of time. A government mandate to start the partnership was inversely related to successful outcomes. Characteristics of LHDs did not predict partnership effectiveness. CONCLUSIONS: Financial support, having a broader array of partners, and allowing sufficient time for partnerships to succeed contribute to partnership effectiveness. Further study-using objective outcome measures-is needed to examine the effects of organizational and community characteristics on the effectiveness of local public health system partnerships. PMID:15736335

  15. Visualization of localization microscopy data.

    PubMed

    Baddeley, David; Cannell, Mark B; Soeller, Christian

    2010-02-01

    Localization microscopy techniques based on localizing single fluorophore molecules now routinely achieve accuracies better than 30 nm. Unlike conventional optical microscopies, localization microscopy experiments do not generate an image but a list of discrete coordinates of estimated fluorophore positions. Data display and analysis therefore generally require visualization methods that translate the position data into conventional images. Here we investigate the properties of several widely used visualization techniques and show that a commonly used algorithm based on rendering Gaussians may lead to a 1.44-fold loss of resolution. Existing methods typically do not explicitly take sampling considerations into account and thus may produce spurious structures. We present two additional visualization algorithms, an adaptive histogram method based on quad-trees and a Delaunay triangulation based visualization of point data that address some of these deficiencies. The new visualization methods are designed to suppress erroneous detail in poorly sampled image areas but avoid loss of resolution in well-sampled regions. A number of criteria for scoring visualization methods are developed as a guide for choosing among visualization methods and are used to qualitatively compare various algorithms. PMID:20082730

  16. Revertants, low temperature, and correctors reveal the mechanism of F508del-CFTR rescue by VX-809 and suggest multiple agents for full correction.

    PubMed

    Farinha, Carlos M; King-Underwood, John; Sousa, Marisa; Correia, Ana Raquel; Henriques, Bárbara J; Roxo-Rosa, Mónica; Da Paula, Ana Carina; Williams, Jonathan; Hirst, Simon; Gomes, Cláudio M; Amaral, Margarida D

    2013-07-25

    Cystic fibrosis is mostly caused by the F508del mutation, which impairs CFTR protein from exiting the endoplasmic reticulum due to misfolding. VX-809 is a small molecule that rescues F508del-CFTR localization, which recently went into clinical trial but with unknown mechanism of action (MoA). Herein, we assessed if VX-809 is additive or synergistic with genetic revertants of F508del-CFTR, other correctors, and low temperature to determine its MoA. We explored and integrated those various agents in combined treatments, showing how they add to each other to identify their complementary MoA upon correction of F508del-CFTR. Our experimental and modeling data, while compatible with putative binding of VX-809 to NBD1:ICL4 interface, also indicate scope for further synergistic F508del-CFTR correction by other compounds at distinct conformational sites/cellular checkpoints, thus suggesting requirement of combined therapies to fully rescue F508del-CFTR. PMID:23890012

  17. 22 CFR 228.40 - Local procurement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Local procurement. 228.40 Section 228.40... COMMODITIES AND SERVICES FINANCED BY USAID Conditions Governing Source and Nationality of Local Procurement Transactions for USAID Financing § 228.40 Local procurement. Local procurement in the cooperating...

  18. Genetic Algorithms with Local Minimum Escaping Technique

    NASA Astrophysics Data System (ADS)

    Tamura, Hiroki; Sakata, Kenichiro; Tang, Zheng; Ishii, Masahiro

    In this paper, we propose a genetic algorithm(GA) with local minimum escaping technique. This proposed method uses the local minimum escaping techique. It can escape from the local minimum by correcting parameters when genetic algorithm falls into a local minimum. Simulations are performed to scheduling problem without buffer capacity using this proposed method, and its validity is shown.

  19. Computational methods for global/local analysis

    NASA Technical Reports Server (NTRS)

    Ransom, Jonathan B.; Mccleary, Susan L.; Aminpour, Mohammad A.; Knight, Norman F., Jr.

    1992-01-01

    Computational methods for global/local analysis of structures which include both uncoupled and coupled methods are described. In addition, global/local analysis methodology for automatic refinement of incompatible global and local finite element models is developed. Representative structural analysis problems are presented to demonstrate the global/local analysis methods.

  20. Local-scale dynamics and local drivers of bushmeat trade.

    PubMed

    Nyaki, Angela; Gray, Steven A; Lepczyk, Christopher A; Skibins, Jeffrey C; Rentsch, Dennis

    2014-10-01

    Bushmeat management policies are often developed outside the communities in which they are to be implemented. These policies are also routinely designed to be applied uniformly across communities with little regard for variation in social or ecological conditions. We used fuzzy-logic cognitive mapping, a form of participatory modeling, to compare the assumptions driving externally generated bushmeat management policies with perceptions of bushmeat trade dynamics collected from local community members who admitted to being recently engaged in bushmeat trading (e.g., hunters, sellers, consumers). Data were collected during 9 workshops in 4 Tanzanian villages bordering Serengeti National Park. Specifically, we evaluated 9 community-generated models for the presence of the central factors that comprise and drive the bushmeat trade and whether or not models included the same core concepts, relationships, and logical chains of reasoning on which bushmeat conservation policies are commonly based. Across local communities, there was agreement about the most central factors important to understanding the bushmeat trade (e.g., animal recruitment, low income, and scarcity of food crops). These matched policy assumptions. However, the factors perceived to drive social-ecological bushmeat trade dynamics were more diverse and varied considerably across communities (e.g., presence or absence of collaborative law enforcement, increasing human population, market demand, cultural preference). Sensitive conservation issues, such as the bushmeat trade, that require cooperation between communities and outside conservation organizations can benefit from participatory modeling approaches that make local-scale dynamics and conservation policy assumptions explicit. Further, communities' and conservation organizations' perceptions need to be aligned. This can improve success by allowing context appropriate policies to be developed, monitored, and appropriately adapted as new evidence is

  1. Dynamical Localization in Molecular Systems.

    NASA Astrophysics Data System (ADS)

    Wang, Xidi

    In the first four chapters of this thesis we concentrate on the Davydov model which describes the vibrational energy quanta of Amide I bonds (C=O bonds on the alpha -helix) coupled to the acoustic phonon modes of the alpha-helix backbone in the form of a Frohlich Hamiltonian. Following a brief introduction in chapter one, in chapter two we formulate the dynamics of vibrational quanta at finite temperature by using coherent state products. The fluctuation-dissipation relation is derived. At zero temperature, in the continuum limit, we recover the original results of Davydov. We also achieve good agreement with numerical simulations. In chapter three, the net contraction of the lattice is calculated exactly at any temperature, and its relation to the so -call "topological stability" of the Davydov soliton is discussed. In the second section of the chapter three we calculate the overtone spectra of crystalline acetanilide (according to some opinions ACN provides experimental evidence for the existence of Davydov solitons). Good agreement with experimental data has been obtained. In chapter four we study the self-trapped vibrational excitations by the Quantum Monte Carlo technique. For a single excitation, the temperature dependence of different physical observables is calculated. The quasi-particle which resembles the Davydov soliton has been found to be fairly narrow using the most commonly used data for the alpha -helix; at temperatures above a few Kelvin, the quasi-particle reaches its smallest limit (extends over three sites), which implies diffusive motion of the small polaron-like quasi-particle at high temperatures. For the multi-excitation case, bound pairs and clusters of excitations are found at low temperatures; they gradually dissociate when the temperature of the system is increased as calculated from the density-density correlation function. In the last chapter of this thesis, we study a more general model of dynamical local modes in molecular systems

  2. Indoor localization using magnetic fields

    NASA Astrophysics Data System (ADS)

    Pathapati Subbu, Kalyan Sasidhar

    Indoor localization consists of locating oneself inside new buildings. GPS does not work indoors due to multipath reflection and signal blockage. WiFi based systems assume ubiquitous availability and infrastructure based systems require expensive installations, hence making indoor localization an open problem. This dissertation consists of solving the problem of indoor localization by thoroughly exploiting the indoor ambient magnetic fields comprising mainly of disturbances termed as anomalies in the Earth's magnetic field caused by pillars, doors and elevators in hallways which are ferromagnetic in nature. By observing uniqueness in magnetic signatures collected from different campus buildings, the work presents the identification of landmarks and guideposts from these signatures and further develops magnetic maps of buildings - all of which can be used to locate and navigate people indoors. To understand the reason behind these anomalies, first a comparison between the measured and model generated Earth's magnetic field is made, verifying the presence of a constant field without any disturbances. Then by modeling the magnetic field behavior of different pillars such as steel reinforced concrete, solid steel, and other structures like doors and elevators, the interaction of the Earth's field with the ferromagnetic fields is described thereby explaining the causes of the uniqueness in the signatures that comprise these disturbances. Next, by employing the dynamic time warping algorithm to account for time differences in signatures obtained from users walking at different speeds, an indoor localization application capable of classifying locations using the magnetic signatures is developed solely on the smart phone. The application required users to walk short distances of 3-6 m anywhere in hallway to be located with accuracies of 80-99%. The classification framework was further validated with over 90% accuracies using model generated magnetic signatures representing

  3. Edge Localized Mode Control in DIII-D Using Magnetic Perturbation-Induced Pedestal Transport Changes

    SciTech Connect

    Moyer, R A; Burrell, K H; Evans, T E; Fenstermacher, M E; Joseph, I; Osborne, T H; Schaffer, M J; Snyder, P B; Watkins, J G; Baylor, L; Becoulet, M; Boedo, J A; Brooks, N H; Doyle, E J; Finken, K; Gohil, P; Groth, M; Hollmann, E M; Jackson, G L; Jernigan, T; Kasilov, S; Lasnier, C J; Leonard, A W; Lehnen, M; Lonnroth, J; Nardon, E; Parail, V; Porter, G D; Rhodes, T L; Rudakov, D L; Runov, A; Schmitz, O; Schneider, R; Thomas, D M; Thomas, P; Wang, G; West, W P; Yan, L; Yu, J H; Zeng, L

    2006-09-27

    Edge localized mode (ELM) control is a critical issue for ITER because the impulsive power loading from ELMs is predicted to limit the divertor lifetime to only a few hundred full-length pulses. Consequently, a technique that replaces the ELM-induced transport with more continuous transport while preserving the H-mode pedestal height and core performance would significantly improve the viability of ITER. One approach is to use edge resonant magnetic perturbations (RMPs) to enhance pedestal transport enough to reduce the pedestal pressure gradient {del}p{sub ped} below the stability limit for Type I ELMs. In DIII-D, n = 3 RMPs have been used to eliminate Type I ELMs when the edge safety factor is in the resonant window q95 {approx} 3.5 without degrading confinement in H-modes with ITER-relevant pedestal collisionalities v*{sub e} {approx} 0.2. The RMP reduces {del}p{sub ped} as expected, with {del}p{sub ped} controlled by the RMP amplitude. Linear peeling-ballooning (P-B) stability analysis indicates that the ELMs are suppressed by reducing {del}p{sub ped} below the P-B stability limit. The {del}p{sub ped} reduction results primarily from an increase in particle transport, not electron thermal transport. This result is inconsistent with estimates based on quasi-linear stochastic diffusion theory based on the vacuum field (no screening of the RMP). The particle transport increase is accompanied by changes in toroidal rotation, radial electric field, and density fluctuation level {tilde n} in the pedestal, suggesting increased fluctuation-driven particle transport.

  4. Oregon Health Go Local: A Retrospective Look.

    PubMed

    Ford, Emily; Hannon, Todd

    2010-04-01

    MedlinePlus® Go Local is the National Library of Medicine and National Institutes of Health's Internet resource that allows individuals to find health services in their local communities. Oregon Health Go Local recently joined the network of active Go Local projects. This paper describes the planning and development of Oregon Health Go Local, with a discussion of the success and challenges of initiating such a project. Funding, marketing, volunteer coordination, data acquisition, and taxonomy are discussed. PMID:20640231

  5. Oregon Health Go Local: A Retrospective Look

    PubMed Central

    Ford, Emily; Hannon, Todd

    2010-01-01

    MedlinePlus® Go Local is the National Library of Medicine and National Institutes of Health's Internet resource that allows individuals to find health services in their local communities. Oregon Health Go Local recently joined the network of active Go Local projects. This paper describes the planning and development of Oregon Health Go Local, with a discussion of the success and challenges of initiating such a project. Funding, marketing, volunteer coordination, data acquisition, and taxonomy are discussed. PMID:20640231

  6. Constrained Local UniversE Simulations: a Local Group factory

    NASA Astrophysics Data System (ADS)

    Carlesi, Edoardo; Sorce, Jenny G.; Hoffman, Yehuda; Gottlöber, Stefan; Yepes, Gustavo; Libeskind, Noam I.; Pilipenko, Sergey V.; Knebe, Alexander; Courtois, Hélène; Tully, R. Brent; Steinmetz, Matthias

    2016-05-01

    Near-field cosmology is practised by studying the Local Group (LG) and its neighbourhood. This paper describes a framework for simulating the `near field' on the computer. Assuming the Λ cold dark matter (ΛCDM) model as a prior and applying the Bayesian tools of the Wiener filter and constrained realizations of Gaussian fields to the Cosmicflows-2 (CF2) survey of peculiar velocities, constrained simulations of our cosmic environment are performed. The aim of these simulations is to reproduce the LG and its local environment. Our main result is that the LG is likely a robust outcome of the ΛCDMscenario when subjected to the constraint derived from CF2 data, emerging in an environment akin to the observed one. Three levels of criteria are used to define the simulated LGs. At the base level, pairs of haloes must obey specific isolation, mass and separation criteria. At the second level, the orbital angular momentum and energy are constrained, and on the third one the phase of the orbit is constrained. Out of the 300 constrained simulations, 146 LGs obey the first set of criteria, 51 the second and 6 the third. The robustness of our LG `factory' enables the construction of a large ensemble of simulated LGs. Suitable candidates for high-resolution hydrodynamical simulations of the LG can be drawn from this ensemble, which can be used to perform comprehensive studies of the formation of the LG.

  7. [Symptoms. Localizations: knee, hip, hands, spine, other localizations].

    PubMed

    Pérez Martín, Álvaro

    2014-01-01

    The symptoms of osteoarthritis vary widely from patient to patient, depending especially on the localization on the disease. There is a poor correlation between radiological involvement and pain. In general, symptom onset is gradual and symptoms increase slowly but progressively. The most commonly affected joints are the knees, hips, hands, and spine. The main signs and symptoms are pain, stiffness, joint deformity, and crepitus. Pain is mechanical and its causes are multifactorial; in the initial phases, pain usually manifests in self-limiting episodes but may subsequently be almost constant. The criteria of the American college of Rheumatology for the classification of osteoarthritis of the knee, hip and hands are an aid to classification and standardization but are not useful for diagnosis. Hip osteoarthritis usually produces inguinal pain in the internal and anterior sections of the muscle extending to the knee and, with progression, tends to limit mobility. Knee osteoarthritis is more frequent in women and is usually associated with hand osteoarthritis and obesity. In hand osteoarthritis, the most commonly affected joints are the distal interphalangeal joints, followed by the proximal interphalangeal joints and the trapeziometacarpal joints; the development of Heberden and Bouchard nodes is common; involvement of the trapeziometacarpal joint is called rhizarthrosis and is one of the forms of osteoarthritis that produces the greatest limitation on hand function. Osteoarthritis of the spine affects the facet joints and the vertebral bodies. Other, less frequent, localizations are the foot, elbow and shoulder, which are generally secondary forms of osteoarthritis. PMID:24467955

  8. Del Norte means north to recycling

    SciTech Connect

    Aquino, J.T.

    1998-06-01

    Del Norte Regional Recycling and Transfer Station is owned by the city of Oxnard, California and operated by BLT Enterprises, Inc. The Del Norte facility--located in southwestern Ventura County about an hour northwest of Los Angeles--processes polyethylene terephthalate (PET) and high-density polyethylene (HDPE) plastic containers, aluminum, steel, glass, old corrugated containers (OCC), newspapers, computer printout paper, white and colored ledger paper, coated book, supermix paper, telephone books, and old magazines. According to the company, there has been virtually no community opposition to the site. The facility has few neighbors, and those are agricultural. To keep the community relationship strong, the facility`s design and location all but eliminated odor and noise complaints. The building was designed against the prevailing wind pattern, and BLT processes odorous material fast. A misting system installed for dust suppression also can be used with a solution for odor control should the need arise.

  9. del, Einstein, Mach, Gamow, and Lanczos: Gödel's remarkable excursion into cosmology

    NASA Astrophysics Data System (ADS)

    Rindler, Wolfgang

    2009-06-01

    This article is an expanded version of a talk given at the International Symposium Celebrating the 100th Birthday of Kurt Gödel (Vienna, 2006). It seeks to trace the path which led this preeminent mathematical logician to discover one of the famous results of General Relativity, the rotating Gödel Universe. This universe has some remarkable properties, which gave the philosophers plenty to worry about. It allows a person to travel into his own past, with all the ensuing causal paradoxes; it allows no unique temporal ordering of events; and though Gödel's Universe is rigid and infinite, the Foucault pendulum planes everywhere in it rotate in unison, a clear affront to adherents of Mach's Principle. We also discuss some lesser known precursors in the field, who just missed discovering Gödel's universe. While the article gives all the necessary derivations in simplified form (for example, of the metric and its geodesics), much of it should be accessible to the general reader, who can simply skip most of the mathematics. [Reprinted, with permission, from Kurt Gödel and the Foundations of Mathematics: Horizons of Truth, edited by Matthias Baaz, Christos H. Papadimitriou, Dana S. Scott, Hilary Putnam, and Charles L. Harper, Jr. (Cambridge U. P., New York, 2009).

  10. Procesamiento Digital de Imagenes del Cometa Halley

    NASA Astrophysics Data System (ADS)

    Ferrin, L.; Fuenmayor, F.; Naranjo, O.; Bulka, P.; Mendoza, C.

    1987-05-01

    Se reportan observaciones fotográficas del cometa Halley, obtenidas con los telescopios Schmidt de 1-m del CIDA, y de 35 cms de la ULA. Se hicieron exposiciones desde 2 segundos a 30 minutos y se utilizaron emulsiones IIa-O, 103a-F, y 103a-D, guladas manualmente 0 automaticámente. Las imágenes fueron digitalizadas con el microdensitómetro PDS, y procesadas con el sistema HACIENDA del CCIBM. Se experimentó con la Transformada de Fourier en dos dimensiones, y con la aplicación de filtros de paso alto y bajo. Se encontró que el metodo de "autocorrelación" es el mejor para separar "la vegetación" de "la montaña". Se aplicaron diversas técnicas a fin de cubrir ambos extremos: a) enfatizar detalles débiles en la cola, y b) penetrar en las regiones más intensas de la coma. Se lograron ambos objetivos. Detalles en la cola permitieron determinar velocidades de propagación de unos 50 a 90 kms/ seg. Se pudieron detectar no menos de tres perturbaciones en "Y", y una en 5? Co de Cisne). Se cree que las primeras están asociadas a eventos de desconexión. Se puede separar la cola de gas de la de polvo. Las fotos de color permiten enfatizar diferentes regiones espectrales con mayor claridad aún. El "balance" del color puede ser hecho con la computadora.

  11. MALARIA VECTORS IN SAN JOSÉDEL GUAVIARE, ORINOQUIA, COLOMBIA

    PubMed Central

    JIMÉNEZ, IRENE P.; CONN, JAN E.; BROCHERO, HELENA

    2015-01-01

    This study was conducted to determine Anopheles species composition and their natural infectivity by human Plasmodium in 2 localities with the highest malaria transmission in San Jose del Guaviare, Guaviare, Colombia. A total of 1,009 Anopheles mosquitoes were collected using human landing catches during 8 months in 2010. Anopheles darlingi was the most abundant (83.2%) followed by An. albitarsis s.l. (8.6%), Anopheles braziliensis (3.8%), An. oswaldoi s.l. (1%), and An. rangeli (0.3%). Anopheles darlingi showed the highest human biting rate, and it was found naturally infected with Plasmodium vivax VK210 (0.119%) using enzyme-linked immunosorbent assays. All species were collected biting both indoors and outdoors. Anopheles darlingi showed biting activity overnight with an indoor peak between 1200–0100 h. Therefore, we recommend that malaria prevention strategies focus on 1) insecticide-treated nets to reduce human–vector contact when people are most exposed and unprotected; 2) accurate diagnoses; 3) adequate treatment for patients; 4) more timely epidemiological notification; and 5) improved entomological surveillance. PMID:25102591

  12. Localization of Peptidases in Lactococci

    PubMed Central

    Tan, Paris S. T.; Chapot-Chartier, Marie-Pierre; Pos, Klaas M.; Rousseau, Micheline; Boquien, Clair-Yves; Gripon, Jean-Claude; Konings, Wil N.

    1992-01-01

    The localization of two aminopeptidases, an X-prolyl-dipeptidyl aminopeptidase, an endopeptidase, and a tripeptidase in Lactococcus lactis was studied. Polyclonal antibodies raised against each purified peptidase are specific and do not cross-react with other peptidases. Experiments were performed by immunoblotting after cell fractionation and by electron microscopy of immunogold-labeled peptidases. All peptidases were found to be intracellular. However, immunogold studies showed a peripheral labeling of the X-prolyl-dipeptidyl aminopeptidase, the tripeptidase, and the endopeptidase. This peripheral location was further supported by the detection of these three enzymes in cell membrane fractions in which none of the two aminopeptidases was present. Images PMID:16348629

  13. A Localized Ensemble Kalman Smoother

    NASA Technical Reports Server (NTRS)

    Butala, Mark D.

    2012-01-01

    Numerous geophysical inverse problems prove difficult because the available measurements are indirectly related to the underlying unknown dynamic state and the physics governing the system may involve imperfect models or unobserved parameters. Data assimilation addresses these difficulties by combining the measurements and physical knowledge. The main challenge in such problems usually involves their high dimensionality and the standard statistical methods prove computationally intractable. This paper develops and addresses the theoretical convergence of a new high-dimensional Monte-Carlo approach called the localized ensemble Kalman smoother.

  14. Local Observation in Eternal Inflation

    NASA Astrophysics Data System (ADS)

    Hartle, James; Hawking, S. W.; Hertog, Thomas

    2011-04-01

    We consider landscape models that admit several regions where the conditions for eternal inflation hold. It is shown that one can use the no-boundary wave function to calculate small departures from homogeneity within our past light cone despite the possibility of much larger fluctuations on super horizon scales. The dominant contribution comes from the history exiting eternal inflation at the lowest value of the potential. In a class of landscape models this predicts a tensor to scalar ratio of about 10%. In this way the no-boundary wave function defines a measure for the prediction of local cosmological observations.

  15. State and Local Government Partnership

    SciTech Connect

    Barton, Alexander; Rinebold, Joel; Aresta, Paul

    2012-03-30

    The State and Local Government Partnership project has built relationships between the Department of Energy (DOE), regional states, and municipalities. CCAT implemented this project using a structure that included leadership by the DOE. Outreach was undertaken through collaborative meetings, workshops, and briefings; the development of technical models and local energy plans; support for state stakeholder groups; and implementation of strategies to facilitate the deployment of hydrogen and fuel cell technologies. The final guidance documents provided to stakeholders consisted of individual strategic state “Roadmaps” to serve as development plans. These “Roadmaps” confirm economic impacts, identify deployment targets, and compare policies and incentives for facility development in each of the regional states. The partnerships developed through this project have improved the exchange of knowledge between state and local government stakeholders and is expected to increase the deployment of hydrogen and fuel cell technologies in early market applications, consistent with the DOE’s market transformation efforts. Technically accurate and objective information was, and continues to be, provided to improve public and stakeholder perceptions regarding the use of hydrogen and fuel cell technologies. Based on the “Roadmaps” and studies conducted for this project, there is the potential to generate approximately 10.75 million megawatt hours (MWh) of electricity annually from hydrogen and fuel cell technologies at potential host sites in the Northeast regional states, through the development of 1,364 to 1,818 megawatts (MW) of fuel cell electric generation capacity. Currently, the region has approximately 1,180 companies that are part of the growing hydrogen and fuel cell industry supply chain in the region. These companies are estimated to have over $1 billion in annual revenue and investment, contribute more than $51 million in annual state and local tax revenue

  16. [Diagnostic laparoscopy under local anaesthesia].

    PubMed

    Grantcharov, Teodor P; Schulze, Svend

    2005-11-14

    Laparoscopy under local anaesthesia (LULA) is a safe, feasible and well-tolerated procedure. LULA has been successfully used for such outpatient gynaecological procedures as diagnosis of chronic pelvic pain and sterilisation. Single studies have indicated that LULA can be performed for diagnosis of possible intra-abdominal catastrophe in ICU patients, appendectomy and preperitoneal inguinal hernia repair. LULA in abdominal surgery for diagnosis of conditions presenting with acute lower abdominal pain is being introduced at our institution. This paper describes the possible applications of LULA in current practice as well as the technical aspects of the procedure. PMID:16287520

  17. Anderson localization from classical trajectories

    NASA Astrophysics Data System (ADS)

    Brouwer, Piet W.; Altland, Alexander

    2008-08-01

    We show that Anderson localization in quasi-one-dimensional conductors with ballistic electron dynamics, such as an array of ballistic chaotic cavities connected via ballistic contacts, can be understood in terms of classical electron trajectories only. At large length scales, an exponential proliferation of trajectories of nearly identical classical action generates an abundance of interference terms, which eventually leads to a suppression of transport coefficients. We quantitatively describe this mechanism in two different ways: the explicit description of transition probabilities in terms of interfering trajectories, and an hierarchical integration over fluctuations in the classical phase space of the array cavities.

  18. Hair transplant and local anesthetics.

    PubMed

    Lam, Samuel M

    2013-10-01

    Hair restoration is an art and a science that requires an experienced and dedicated surgeon and team to achieve consistently superior outcomes. In addition to discussion of local anesthetic in use for hair restoration, this article emphasizes the pearls and pitfalls that are involved at every phase of the procedure including judgment, hairline design, donor harvesting, recipient-site creation, graft preparation, and graft placement. Two recent advances in the field are highlighted: the use of regenerative medicine (platelet-rich plasma and ACell), and developments in follicular-unit extraction as an alternative to traditional linear donor harvesting. PMID:24093656

  19. Genetic Algorithms and Local Search

    NASA Technical Reports Server (NTRS)

    Whitley, Darrell

    1996-01-01

    The first part of this presentation is a tutorial level introduction to the principles of genetic search and models of simple genetic algorithms. The second half covers the combination of genetic algorithms with local search methods to produce hybrid genetic algorithms. Hybrid algorithms can be modeled within the existing theoretical framework developed for simple genetic algorithms. An application of a hybrid to geometric model matching is given. The hybrid algorithm yields results that improve on the current state-of-the-art for this problem.

  20. Nuclear scission and quantum localization.

    PubMed

    Younes, W; Gogny, D

    2011-09-23

    We examine nuclear scission within a fully quantum-mechanical microscopic framework, focusing on the nonlocal aspects of the theory. Using (240)Pu hot fission as an example, we discuss the identification of the fragments and the calculation of their kinetic, excitation, and interaction energies, through the localization of the orbital wave functions. We show that the disentanglement of the fragment wave functions is essential to the quantum-mechanical definition of scission and the calculation of physical observables. Finally, we discuss the fragments' prescission excitation mechanisms and give a nonadiabatic description of their evolution beyond scission. PMID:22026846

  1. Visualization of the Gödel universe

    NASA Astrophysics Data System (ADS)

    Buser, M.; Kajari, E.; Schleich, W. P.

    2013-01-01

    The standard model of modern cosmology, which is based on the Friedmann-Lemaître-Robertson-Walker metric, allows the definition of an absolute time. However, there exist (cosmological) models consistent with the theory of general relativity for which such a definition cannot be given since they offer the possibility for time travel. The simplest of these models is the cosmological solution discovered by Kurt Gödel, which describes a homogeneous, rotating universe. Disregarding the paradoxes that come along with the abolishment of causality in such space-times, we are interested in the purely academic question of how an observer would visually perceive the time travel of an object in Gödel's universe. For this purpose, we employ the technique of ray tracing, a standard tool in computer graphics, and visualize various scenarios to bring out the optical effects experienced by an observer located in this universe. In this way, we provide a new perspective on the space-time structure of Gödel's model.

  2. A localization model to localize multiple sources using Bayesian inference

    NASA Astrophysics Data System (ADS)

    Dunham, Joshua Rolv

    Accurate localization of a sound source in a room setting is important in both psychoacoustics and architectural acoustics. Binaural models have been proposed to explain how the brain processes and utilizes the interaural time differences (ITDs) and interaural level differences (ILDs) of sound waves arriving at the ears of a listener in determining source location. Recent work shows that applying Bayesian methods to this problem is proving fruitful. In this thesis, pink noise samples are convolved with head-related transfer functions (HRTFs) and compared to combinations of one and two anechoic speech signals convolved with different HRTFs or binaural room impulse responses (BRIRs) to simulate room positions. Through exhaustive calculation of Bayesian posterior probabilities and using a maximal likelihood approach, model selection will determine the number of sources present, and parameter estimation will result in azimuthal direction of the source(s).

  3. Localized Excitons in Carbon Nanotubes.

    NASA Astrophysics Data System (ADS)

    Adamska, Lyudmyla; Doorn, Stephen K.; Tretiak, Sergei

    2015-03-01

    It has been historically known that unintentional defects in carbon nanotubes (CNTs) may fully quench the fluorescence. However, some dopants may enhance the fluorescence by one order of magnitude thus turning the CNTs, which are excellent light absorbers, in good emitters. We have correlated the experimentally observed photoluminescence spectra to the electronic structure simulations. Our experiment reveals multiple sharp asymmetric emission peaks at energies 50-300 meV red-shifted from that of the lowest bright exciton peak. Our simulations suggest an association of these peaks with deep trap states tied to different specific chemical adducts. While the wave functions of excitons in undoped CNTs are delocalized, those of the deep-trap states are strongly localized and pinned to the dopants. These findings are consistent with the experimental observation of asymmetric broadening of the deep trap emission peaks, which can result from scattering of acoustic phonons on localized excitons. Our work lays the foundation to utilize doping as a generalized route for wave function engineering and direct control of carrier dynamics in SWCNTs toward enhanced light emission properties for photonic applications.

  4. Localized control of oxidized RNA.

    PubMed

    Zhan, Yu; Dhaliwal, James S; Adjibade, Pauline; Uniacke, James; Mazroui, Rachid; Zerges, William

    2015-11-15

    The oxidation of biological molecules by reactive oxygen species (ROS) can render them inactive or toxic. This includes the oxidation of RNA, which appears to underlie the detrimental effects of oxidative stress, aging and certain neurodegenerative diseases. Here, we investigate the management of oxidized RNA in the chloroplast of the green alga Chlamydomonas reinhardtii. Our immunofluorescence microscopy results reveal that oxidized RNA (with 8-hydroxyguanine) is localized in the pyrenoid, a chloroplast microcompartment where CO2 is assimilated by the Calvin cycle enzyme Rubisco. Results of genetic analyses support a requirement for the Rubisco large subunit (RBCL), but not Rubisco, in the management of oxidized RNA. An RBCL pool that can carry out such a 'moonlighting' function is revealed by results of biochemical fractionation experiments. We also show that human (HeLa) cells localize oxidized RNA to cytoplasmic foci that are distinct from stress granules, processing bodies and mitochondria. Our results suggest that the compartmentalization of oxidized RNA management is a general phenomenon and therefore has some fundamental significance. PMID:26449969

  5. Building a local research consortium.

    PubMed

    Martin, P A

    1994-05-01

    Although state, regional, and national networking often are critical to the nurse researchers, local support that is broader than what is found in any single agency may be the foundation needed by clinicians who want "more" research than that prescribed by their current role. More formal consortiums have successfully implemented a variety of research projects and are another possibility to explore (Beaman & Strader, 1990; Bolton, 1991; Chenitz et al., 1990; Keefe et al., 1988; Thiele, 1989). Another option is some state nurses' associations that have formal research assemblies (eg., Ohio Nurses Association, Assembly of Nurse Researchers). However, forming a local, less formal group with a few expert advisors may supply the energy and momentum necessary for both using and conducting research at a grassroots level. The expert advisors should be research-trained nurses (almost always with a PhD or DNS) who are active group members. Although Fitzpatrick encouraged collaborative research and writing early in the history of Applied Nursing Research (Fitzpatrick, 1989), in 1993 approximately two thirds of the articles in Applied Nursing Research still were single authored. Nurses are not using collaboration to its fullest extent. An informal group in one community has been one way to release the scholarship that was latent in many nurses. PMID:8031105

  6. Local Effects of Delayed Food

    PubMed Central

    Davison, Michael; Baum, William M

    2007-01-01

    Five pigeons were trained on a procedure in which seven concurrent variable-interval schedules arranged seven different food–rate ratios in random sequence in each session. Each of these components lasted for 10 response-produced food deliveries, and components were separated by 10-s blackouts. We varied delays to food (signaled by blackout) between the two response alternatives in an experiment with three phases: In Phase 1, the delay on one alternative was 0 s, and the other was varied between 0 and 8 s; in Phase 2, both delays were equal and were varied from 0 to 4 s; in Phase 3, the two delays summed to 8 s, and each was varied from 1 to 7 s. The results showed that increasing delay affected local choice, measured by a pulse in preference, in the same way as decreasing magnitude, but we found also that increasing the delay at the other alternative increased local preference. This result casts doubt on the traditional view that a reinforcer strengthens a response depending only on the reinforcer's value discounted by any response–reinforcer delay. The results suggest that food guides, rather than strengthens, behavior. PMID:17465314

  7. Local area networks for radiology.

    PubMed

    Dwyer, S J; Mankovich, N J; Cox, G G; Bauman, R A

    1988-11-01

    This article is a tutorial on local area networks (LAN) for radiology applications. LANs are being implemented in radiology departments for the management of text and images, replacing the inflexible point-to-point wiring between two devices (computer-to-terminal). These networks enable the sharing of computers and computer devices, reduce equipment costs, and provide improved reliability. Any LAN must include items from the following four categories: transmission medium, topology, data transmission mode, and access protocol. Media for local area networks are twisted pair, coaxial, and optical fiber cables. The topology of these networks include the star, ring, bus, tree, and circuit-switching. Data transmission modes are either analog signals or digital signals. Access protocol methods include the broadcast bus system and the ring system. A performance measurement for a LAN is the throughput rate as a function of the number of active computer nodes. Standards for LANs help to ensure that products purchased from multiple manufacturers will operate successfully. PMID:3154655

  8. Developing Photo Activated Localization Microscopy

    NASA Astrophysics Data System (ADS)

    Hess, Harald

    2015-03-01

    Photo Activated Localization Microscopy, PALM, acquires super-resolution images by activating a subset of activatable fluorescent labels and estimating the center of the each molecular label to sub-diffractive accuracy. When this process is repeated thousands of times for different subsets of molecules, then an image can be rendered from all the center coordinates of the molecules. I will describe the circuitous story of its development that began with another super-resolution technique, NSOM, developed by my colleague Eric Betzig, who imaged single molecules at room temperature, and later we spectrally resolved individual luminescent centers of quantum wells. These two observations inspired a generalized path to localization microscopy, but that path was abandoned because no really useful fluorescent labels were available. After a decade of nonacademic industrial pursuits and the subsequent freedom of unemployment, we came across a class of genetically expressible fluorescent proteins that were switchable or convertible that enabled the concept to be implemented and be biologically promising. The past ten years have been very active with many groups exploring applications and enhancements of this concept. Demonstrating significant biological relevance will be the metric if its success.

  9. Gravity localization on hybrid branes

    NASA Astrophysics Data System (ADS)

    Veras, D. F. S.; Cruz, W. T.; Maluf, R. V.; Almeida, C. A. S.

    2016-03-01

    This work deals with gravity localization on codimension-1 brane worlds engendered by compacton-like kinks, the so-called hybrid branes. In such scenarios, the thin brane behavior is manifested when the extra dimension is outside the compact domain, where the energy density is non-trivial, instead of asymptotically as in the usual thick brane models. The zero mode is trapped in the brane, as required. The massive modes, although not localized in the brane, have important phenomenological implications such as corrections to the Newton's law. We study such corrections in the usual thick domain wall and in the hybrid brane scenarios. By means of suitable numerical methods, we attain the mass spectrum for the graviton and the corresponding wavefunctions. The spectra possess the usual linearly increasing behavior from the Kaluza-Klein theories. Further, we show that the 4D gravitational force is slightly increased at short distances. The first eigenstate contributes highly for the correction to the Newton's law. The subsequent normalized solutions have diminishing contributions. Moreover, we find out that the phenomenology of the hybrid brane is not different from the usual thick domain wall. The use of numerical techniques for solving the equations of the massive modes is useful for matching possible phenomenological measurements in the gravitational law as a probe to warped extra dimensions.

  10. Severe Local Storms Cultural Heritage

    NASA Astrophysics Data System (ADS)

    Gladich, I.; Gallai, I.; Giaiotti, D. B.; Morgan, G. M.; Stel, F.

    2009-09-01

    Local storms always had a deep impact on people communities, mainly because of the severe damage caused, because of their unpredictability and, up to a few years ago, even because of the lack of knowledge and awareness on their physical origin. Because of this large impact on real life and on imagination, people needed and wanted to describe and report the occurrence of these events, giving them suited names. Often, these nouns are related to the myth developed to explain the cause of the events. In this work, a short presentation and description of the popular nouns used to describe severe local storm events in different areas of the World is given. Countries taken into account span from Italy, moving toward Africa and reaching a few communities of Native Americans. The etymology of the names gives interesting information, useful even under the anthropological point of view, on the Culture and Believes of the peoples who adopted them. This research work is the result of an underground activity carried out in the last ten years by the authors, during their contacts with students and researchers coming from different Countries and mainly met at the International Center for Theoretical Physics in Trieste.

  11. ISS Local Environment Spectrometers (ISLES)

    NASA Technical Reports Server (NTRS)

    Krause, Linda Habash; Gilchrist, Brian E.

    2014-01-01

    In order to study the complex interactions between the space environment surrounding the ISS and the ISS surface materials, we propose to use lowcost, high-TRL plasma sensors on the ISS robotic arm to probe the ISS space environment. During many years of ISS operation, we have been able to condut effective (but not perfect) extravehicular activities (both human and robotic) within the perturbed local ISS space environment. Because of the complexity of the interaction between the ISS and the LEO space environment, there remain important questions, such as differential charging at solar panel junctions (the so-called "triple point" between conductor, dielectric, and space plasma), increased chemical contamination due to ISS surface charging and/or thruster activation, water dumps, etc, and "bootstrap" charging of insulating surfaces. Some compelling questions could synergistically draw upon a common sensor suite, which also leverages previous and current MSFC investments. Specific questions address ISS surface charging, plasma contactor plume expansion in a magnetized drifting plasma, and possible localized contamination effects across the ISS.

  12. Hardy's test for local realism

    NASA Astrophysics Data System (ADS)

    Nguyen, Quynh; Dregli, Aurelio

    2014-03-01

    We demonstrated the violation of Bell inequality using entangled photons produced by spontaneous parametric down-conversion. The experiment is based on a local realism test originally proposed by Lucien Hardy. Polarized entangled photons is produced in down-conversion through a pair of beta barium borate crystals. Polarization is adjusted by half wave plates and quartz plates. Single photons travel down two separate paths, each pass through a half-wave plate and a broad band polarizing beam splitter. Light from the beam splitter is collected by lens and focused into optic fibers that direct light into a single photon counting module. Coincidence counting is done using time-to-amplitude converter/single-channel-analyzer units. The probabilities in Bell-Clauser-Horne inequality is calculated by the ratio of the measured coincidence counts on the transmitted laser beams to the total number of coincidence. The counting is done by a LabVIEW program. We find the data to violate local realism by 30 standard deviation. The experiment is based on straight forward quantum mechanical calculations and experimental techniques more accessible to undergraduate students than other methods of testing Bell inequalities.

  13. Glacial geomorphology of the Torres del Paine region (southern Patagonia): Implications for glaciation, deglaciation and paleolake history

    NASA Astrophysics Data System (ADS)

    García, Juan-Luis; Hall, Brenda L.; Kaplan, Michael R.; Vega, Rodrigo M.; Strelin, Jorge A.

    2014-01-01

    The processes affecting paleoclimate variability and Pleistocene glacial landscape development in the southern mid-latitudes remain poorly understood, in part because of the scarcity of comprehensive, well-studied records. Glacial landforms are invaluable for reconstructing past ice-sheet, climate, and associated environmental changes along the southern Andes, but there are significant spatial and temporal gaps in existing data. In this paper, we present new geomorphic and sedimentologic analyses, including surficial maps, for the Torres del Paine region (51°S, 73°W), southern South America. Our findings provide a new framework for understanding changes in the regional glacier history and Pleistocene landscape development. Glacial extent during the local last glacial maximum (LGM) remains unknown but new chronological data supported by geomorphic evidence afford evidence for a larger ice sheet at Torres del Paine than previously assumed. Deglaciation from the local LGM was underway by 17,400 ± 200 (1σ) cal. yr. BP. As opposed to previous suggestions, we have found that most of the moraines fringing the lakes in the Torres del Paine national park were deposited during a late-glacial expansion that occurred between 14,100 and 12,500 cal. yr. BP. Late-glacial advances also have been documented recently for the Última Esperanza and Lago Argentino basins to the south and north of Torres del Paine, respectively, suggesting an overall regional ice response to a climate signal. The Tehuelche paleolake accompanied each of the ice-sheet fluctuations in Torres del Paine. New data document at least three main phases of this paleolake, which drained eastward to the Atlantic Ocean, while the Andes gaps were blocked with ice. During the late phase of glacial lake formation, when water levels reached 125-155 m a.s.l., the lake likely merged with paleolake Consuelo in the Última Esperanza area at the end of the last glaciation. Lake Tehuelche in Torres del Paine had drained

  14. Morphology, geology and geochemistry of the "Salar del Gran Bajo del Gualicho" (Rio Negro, Argentina)

    USGS Publications Warehouse

    Angelucci, A.; Barbieri, M.; Brodtkorb, A.; Ciccacci, S.; Civitelli, G.; De Barrio, R.; Di, Filippo M.; Fredi, P.; Friedman, I.; Lombardi, S.; Schalamuk, A.I.; Toro, B.

    1996-01-01

    A multidisciplinary study of the Gran Bajo del Gualicho area (Rio Negro - Argentina) was carried out; the aim was to delineate its geological and geomorphological evolution and to estabilish the genesis of salts filling the depression. Climatic conditions were analized first to individuate their role in the present morphogenetic processes; moreover the main morphological features of present landscape were examined as well as the stratigraphy of the outcropping formations, and of the Gran Bajo del Gualicho Formation in particular. Finally, a possible geomorphological evolution of the studied area was traced. Geophysical analyses allowed to estabilish that the paleosurface shaped on the crystalline basement is strongly uneven and shows evidence of the strong tectonic phases it underwent. The result of isotope analyses confirmed that the salt deposits on the Gran Bajo del Gualicho bottom were produced by fresh water evaporation, while strontium isotope ratio suggested that such waters were responsible for solubilization of more ancient evaporitic deposits.

  15. A Description of Del Mod and Its Final Evaluation, Final Report, Volume I.

    ERIC Educational Resources Information Center

    Purnell, Charlotte H.; Bolig, John R.

    This monograph presents an overview of five Del Mod System final reports, comments by the project director, financial structure of the Del Mod System, and descriptions of Del Mod Projects. The Del Mod System was concerned with changing the science and mathematics education programs in the state of Delaware. Between 1970 and 1976, Del Mod conducted…

  16. Towards a systematic construction of realistic D-brane models on a del Pezzo singularity

    NASA Astrophysics Data System (ADS)

    Dolan, Matthew J.; Krippendorf, Sven; Quevedo, Fernando

    2011-10-01

    A systematic approach is followed in order to identify realistic D-brane models at toric del Pezzo singularities. Requiring quark and lepton spectrum and Yukawas from D3 branes and massless hypercharge, we are led to Pati-Salam extensions of the Standard Model. Hierarchies of masses, flavour mixings and control of couplings select higher order del Pezzo singularities, minimising the Higgs sector prefers toric del Pezzos with dP 3 providing the most successful compromise. Then a supersymmetric local string model is presented with the following properties at low energies: (i) the MSSM spectrum plus a local B - L gauge field or additional Higgs fields depending on the breaking pattern, (ii) a realistic hierarchy of quark and lepton masses and (iii) realistic flavour mixing between quark and lepton families with computable CKM and PMNS matrices, and CP violation consistent with observations. In this construction, kinetic terms are diagonal and under calculational control suppressing standard FCNC contributions. Proton decay operators of dimension 4, 5, 6 are suppressed, and gauge couplings can unify depending on the breaking scales from string scales at energies in the range 1012-1016 GeV, consistent with TeV soft-masses from moduli mediated supersymmetry breaking. The GUT scale model corresponds to D3 branes at dP 3 with two copies of the Pati-Salam gauge symmetry SU(4) × SU(2) R × SU(2) L . D-brane instantons generate a non-vanishing μ-term. Right handed sneutrinos can break the B - L symmetry and induce a see-saw mechanism of neutrino masses and R-parity violating operators with observable low-energy implications.

  17. Multimodal Assessment of Protein Functional Deficiency Supports Pathogenicity of BRCA1 p.V1688del

    PubMed Central

    De Nicolo, Arcangela; Parisini, Emilio; Zhong, Quan; Palma, Maurizia Dalla; Stoeckert, Kathryn A.; Domchek, Susan M.; Nathanson, Katherine L.; Caligo, Maria A.; Vidal, Marc; Cusick, Michael E.; Garber, Judy E.

    2009-01-01

    Unequivocal discrimination between neutral variants and deleterious mutations is crucial for appropriate counseling of individuals with a BRCA1 or BRCA2 sequence change. An increasing number of variants of uncertain significance (VUSs) are being identified, whose unclassified biological effect poses clinical concerns. A multifactorial likelihood-based approach recently suggested disease causality for BRCA1 p.V1688del, a VUS recurrent in Italian breast/ovarian cancer families. Whether and how this single amino acid deletion in the BRCA1 BRCT domain affects the function of the mutant protein (ΔValBRCA1) has not been elucidated. We undertook comprehensive functional characterization of ΔValBRCA1, comprising comparative structural modeling, analysis of protein stability and associations, and analysis of DNA repair function. Our model predicted BRCT domain destabilization and folding disruption caused by BRCA1 p.V1688del. Consistently, the recombinant ΔValBRCA1 was less stable than wtBRCA1 and, unlike the latter, failed to associate with BRIP1, CtIP, and Rap80, and to re-localize to sites of DNA damage. Yeast two-hybrid analysis revealed a compromised interaction with FHL2 and with KPNA2, which is likely responsible for improper subcellular localization of ΔValBRCA1. In addition, we found four new breast/ovarian cancer families of Italian ancestry who carried this sequence alteration. These results provide the first evidence of the effect of BRCA1 p.V1688del on protein stability and function, supporting the view that it is a deleterious mutation. Multimodal analyses like ours could advance understanding of tumor suppression by BRCA1, and ultimately contribute to developing efficient strategies for screening and characterization of VUSs. PMID:19706752

  18. Causal localizations in relativistic quantum mechanics

    SciTech Connect

    Castrigiano, Domenico P. L. Leiseifer, Andreas D.

    2015-07-15

    Causal localizations describe the position of quantum systems moving not faster than light. They are constructed for the systems with finite spinor dimension. At the center of interest are the massive relativistic systems. For every positive mass, there is the sequence of Dirac tensor-localizations, which provides a complete set of inequivalent irreducible causal localizations. They obey the principle of special relativity and are fully Poincaré covariant. The boosters are determined by the causal position operator and the other Poincaré generators. The localization with minimal spinor dimension is the Dirac localization. Thus, the Dirac equation is derived here as a mere consequence of the principle of causality. Moreover, the higher tensor-localizations, not known so far, follow from Dirac’s localization by a simple construction. The probability of localization for positive energy states results to be described by causal positive operator valued (PO-) localizations, which are the traces of the causal localizations on the subspaces of positive energy. These causal Poincaré covariant PO-localizations for every irreducible massive relativistic system were, all the more, not known before. They are shown to be separated. Hence, the positive energy systems can be localized within every open region by a suitable preparation as accurately as desired. Finally, the attempt is made to provide an interpretation of the PO-localization operators within the frame of conventional quantum mechanics attributing an important role to the negative energy states.

  19. Relative Locality in Curved Spacetime

    NASA Astrophysics Data System (ADS)

    Kowalski-Glikman, Jerzy; Rosati, Giacomo

    2013-07-01

    In this paper we construct the action describing dynamics of the particle moving in curved spacetime, with a nontrivial momentum space geometry. Curved momentum space is the core feature of theories where relative locality effects are present. So far aspects of nonlinearities in momentum space have been studied only for flat or constantly expanding (de Sitter) spacetimes, relying on their maximally symmetric nature. The extension of curved momentum space frameworks to arbitrary spacetime geometries could be relevant for the opportunities to test Planck-scale curvature/deformation of particles momentum space. As a first example of this construction we describe the particle with κ-Poincaré momentum space on a circular orbit in Schwarzschild spacetime, where the contributes of momentum space curvature turn out to be negligible. The analysis of this problem relies crucially on the solution of the soccer ball problem.

  20. Headphone localization of speech stimuli

    NASA Technical Reports Server (NTRS)

    Begault, Durand R.; Wenzel, Elizabeth M.

    1991-01-01

    Recently, three dimensional acoustic display systems have been developed that synthesize virtual sound sources over headphones based on filtering by Head-Related Transfer Functions (HRTFs), the direction-dependent spectral changes caused primarily by the outer ears. Here, 11 inexperienced subjects judged the apparent spatial location of headphone-presented speech stimuli filtered with non-individualized HRTFs. About half of the subjects 'pulled' their judgements toward either the median or the lateral-vertical planes, and estimates were almost always elevated. Individual differences were pronounced for the distance judgements; 15 to 46 percent of stimuli were heard inside the head with the shortest estimates near the median plane. The results infer that most listeners can obtain useful azimuth information from speech stimuli filtered by nonindividualized RTFs. Measurements of localization error and reversal rates are comparable with a previous study that used broadband noise stimuli.

  1. Localized pustulosis induced by betalactams.

    PubMed

    Novalbos, A; Bombín, C; Figueredo, E; Lluch, M; Sastre, J

    2000-01-01

    Localized forms of pustular drug eruptions related to antibiotics are uncommon and their mechanism is still unknown. We describe herein a patient who developed numerous pin-head pustules without erythema in the peribuccal area after ingestion of ceftibuten and amoxicillin. The relationship with these drugs was confirmed by single-blind oral challenges. The following tests were performed: prick and intradermal tests with benzylpenicilloyl polylysine, minor determinant mixture, benzylpenicillin and amoxicillin; patch tests were also carried out with benzylpenicillin, amoxicillin, cloxacillin, cefuroxime, ceftriaxone, cefazolin, ceftibuten and cefaclor. All cutaneous tests were negative. Controlled single-blind challenge tests were performed with amoxicillin, cefadroxil, ceftibuten, cefuroxime, cefaclor, erythromycin and ciprofloxacin. All betalactam antibiotics tested gave a positive reaction, with good tolerance of other antibiotics; this would appear to indicate a specific mechanism of hypersensitivity and not an unspecific reaction to wide spectrum antibiotics. PMID:10923595

  2. Anticipation of Local Epidemics Management

    NASA Astrophysics Data System (ADS)

    Krivy, Ivan

    2008-10-01

    Local epidemics are systems where temporary elements (infected ones) are distributed over a hexagonal or rectangular network of permanent elements (humans). Their relation of being neighbors is considered to be constant. The systems of this type can occur in rest homes, institutes of social care, nursery schools, summer camps, prisons, etc. The process of the infection propagation depends on the neighborhood relation and on the actual distance of the neighbors. It is influenced by delays during the transitive affecting the people and by random effects, the size of which can be diminished by the intervention of health care service. The anticipation of the health care intervention effects was supported by simulation models implemented by means of the object-oriented programming.

  3. String fluid in local equilibrium

    NASA Astrophysics Data System (ADS)

    Schubring, Daniel; Vanchurin, Vitaly

    2014-10-01

    We study the solutions of string fluid equations under the assumption of a local equilibrium which was previously obtained in the context of the kinetic theory. We show that the fluid can be foliated into noninteracting submanifolds whose equations of motion are exactly that of the wiggly strings considered previously by Vilenkin and Carter. In a special case of negligible statistical variance in either the left- or the right-moving directions of microscopic strings, the submanifolds are described by the action of a null-current-carrying chiral string. When both variances vanish the submanifolds are described by the Nambu-Goto action and the string fluid reduces to the string dust introduced by Stachel.

  4. Local hadron calibration with ATLAS

    NASA Astrophysics Data System (ADS)

    Giovannini, Paola; ATLAS Liquid Argon Calorimeter Group

    2011-04-01

    The method of Local Hadron Calibration is used in ATLAS as one of the two major calibration schemes for the reconstruction of jets and missing transverse energy. The method starts from noise suppressed clusters and corrects them for non-compensation effects and for losses due to noise threshold and dead material. Jets are reconstructed using the calibrated clusters and are then corrected for out of cone effects. The performance of the corrections applied to the calorimeter clusters is tested with detailed GEANT4 information. Results obtained with this procedure are discussed both for single pion simulations and for di-jet simulations. The calibration scheme is validated on data, by comparing the calibrated cluster energy in data with Mote Carlo simulations. Preliminary results obtained with GeV collision data are presented. The agreement between data and Monte Carlo is within 5% for the final cluster scale.

  5. Exploring Mars using local resources

    SciTech Connect

    Brody, S.; McKay, C.; Kaplan, D.; Rapp, D.

    1996-03-01

    This paper takes the reader on a {ital second} human expedition to Mars. Following confirmation that life once existed on Mars during the first human mission launched in 2018, crew members of our subsequent mission, assisted by robotic devices, spend two years on Mars pursuing three goals: (1) continue the search for further evidence of ancient life and what may still exist, (2) safely endure their extended stay on Mars, and (3) lay the foundation for the eventual human settlement of the planet. A cornerstone in achieving these three goals, as discussed in the paper, will be the utilization of local resources as we further learn to {open_quote}{open_quote}live off the land{close_quote}{close_quote}. {copyright} {ital 1996 American Institute of Physics.}

  6. Local fat treatments: classification proposal.

    PubMed

    Pinto, Hernán

    2016-01-01

    The poor understanding of the real, intimate action mechanisms behind any aesthetic procedures is a huge problem for many Aesthetic physicians. In addition, nomenclature of and regarding any procedure has become a true barrier when speaking about medical knowledge in the Aesthetic Medicine field since marketing and science often collide one another. Medical procedures for localized fat reduction are very different from each other and it is, at least, inaccurate to refer to all of them plainly as "fat reduction methods." A specific classification has become urgent and its categories should be able to imply what each method entails. For this classification proposal, "reversibility," "membrane disruption or inflammation," and "action selectivity," have been the selected criteria. PMID:27144093

  7. Local intensity adaptive image coding

    NASA Technical Reports Server (NTRS)

    Huck, Friedrich O.

    1989-01-01

    The objective of preprocessing for machine vision is to extract intrinsic target properties. The most important properties ordinarily are structure and reflectance. Illumination in space, however, is a significant problem as the extreme range of light intensity, stretching from deep shadow to highly reflective surfaces in direct sunlight, impairs the effectiveness of standard approaches to machine vision. To overcome this critical constraint, an image coding scheme is being investigated which combines local intensity adaptivity, image enhancement, and data compression. It is very effective under the highly variant illumination that can exist within a single frame or field of view, and it is very robust to noise at low illuminations. Some of the theory and salient features of the coding scheme are reviewed. Its performance is characterized in a simulated space application, the research and development activities are described.

  8. Multi-directional local search

    PubMed Central

    Tricoire, Fabien

    2012-01-01

    This paper introduces multi-directional local search, a metaheuristic for multi-objective optimization. We first motivate the method and present an algorithmic framework for it. We then apply it to several known multi-objective problems such as the multi-objective multi-dimensional knapsack problem, the bi-objective set packing problem and the bi-objective orienteering problem. Experimental results show that our method systematically provides solution sets of comparable quality with state-of-the-art methods applied to benchmark instances of these problems, within reasonable CPU effort. We conclude that the proposed algorithmic framework is a viable option when solving multi-objective optimization problems. PMID:25140071

  9. Local fat treatments: classification proposal

    PubMed Central

    Pinto, Hernán

    2016-01-01

    ABSTRACT The poor understanding of the real, intimate action mechanisms behind any aesthetic procedures is a huge problem for many Aesthetic physicians. In addition, nomenclature of and regarding any procedure has become a true barrier when speaking about medical knowledge in the Aesthetic Medicine field since marketing and science often collide one another. Medical procedures for localized fat reduction are very different from each other and it is, at least, inaccurate to refer to all of them plainly as “fat reduction methods.” A specific classification has become urgent and its categories should be able to imply what each method entails. For this classification proposal, “reversibility,” “membrane disruption or inflammation,” and “action selectivity,” have been the selected criteria. PMID:27144093

  10. Localization of quantum Bernoulli noises

    SciTech Connect

    Wang, Caishi; Zhang, Jihong

    2013-10-15

    The family (∂{sub k},∂{sub k}{sup *}){sub k≥0} of annihilation and creation operators acting on square integrable functionals of a Bernoulli process Z= (Z{sub k}){sub k⩾0} can be interpreted as quantum Bernoulli noises. In this note we consider the operator family (ℓ{sub k},ℓ{sub k}{sup *}){sub k≥0}, where ℓ{sub k}=∂{sub k}E{sub k} with E{sub k} being the conditional expectation (operator) given σ-field σ(Z{sub j}; 0 ⩽j⩽k). We show that ℓ{sub k} (resp. ℓ{sub k}{sup *}) is essentially a kind of localization of the annihilation operator ∂{sub k} (resp. creation operator ∂{sub k}{sup *}). We examine properties of the family (ℓ{sub k},ℓ{sub k}{sup *}){sub k≥0} and prove, among other things, that ℓ{sub k} and ℓ{sub k}{sup *} satisfy a local canonical anti-communication relation and (ℓ{sub k}{sup *}){sub k≥0} forms a mutually orthogonal operator sequence although each ℓ{sub k} is not a projection operator. We find that the operator series Σ{sub k=0}{sup ∞}ℓ{sub k}{sup *}Xℓ{sub k} converges in the strong operator topology for each bounded operator X acting on square integrable functionals of Z. In particular we get an explicit sum of the operator series Σ{sub k=0}{sup ∞}ℓ{sub k}{sup *}ℓ{sub k}. A useful norm estimate on Σ{sub k=0}{sup ∞}ℓ{sub k}{sup *}Xℓ{sub k} is also obtained. Finally we show applications of our main results to quantum dynamical semigroups and quantum probability.

  11. Golgi Localization of Syne-1

    PubMed Central

    Gough, Lisa Lucio; Fan, Jun; Chu, Stephen; Winnick, Shawn; Beck, Kenneth A.

    2003-01-01

    We have previously identified a Golgi-localized spectrin isoform by using an antibody to the β-subunit of erythrocyte spectrin. In this study, we show that a screen of a λgt11 expression library resulted in the isolation of an ∼5-kb partial cDNA from a Madin-Darby bovine kidney (MDBK) cell line, which encoded a polypeptide of 1697 amino acids with low, but detectable, sequence homology to spectrin (37%). A blast search revealed that this clone overlaps with the 5′ end of a recently identified spectrin family member Syne-1B/Nesprin-1β, an alternately transcribed gene with muscle-specific forms that bind acetylcholine receptor and associate with the nuclear envelope. By comparing the sequence of the MDBK clone with sequence data from the human genome database, we have determined that this cDNA represents a central portion of a very large gene (∼500 kb), encoding an ∼25-kb transcript that we refer to as Syne-1. Syne-1 encodes a large polypeptide (8406 amino acids) with multiple spectrin repeats and a region at its amino terminus with high homology to the actin binding domains of conventional spectrins. Golgi localization for this spectrin-like protein was demonstrated by expression of epitope-tagged fragments in MDBK and COS cells, identifying two distinct Golgi binding sites, and by immunofluorescence microscopy by using several different antibody preparations. One of the Golgi binding domains on Syne-1 acts as a dominant negative inhibitor that alters the structure of the Golgi complex, which collapses into a condensed structure near the centrosome in transfected epithelial cells. We conclude that the Syne-1 gene is expressed in a variety of forms that are multifunctional and are capable of functioning at both the Golgi and the nuclear envelope, perhaps linking the two organelles during muscle differentiation. PMID:12808039

  12. Molecular insights into intracellular RNA localization

    PubMed Central

    Blower, Michael D.

    2013-01-01

    Localization of mRNAs to specific destinations within a cell or an embryo is important for local control of protein expression. mRNA localization is well-known to function in very large and polarized cells such as neurons, and to facilitate embryonic patterning during early development. However, recent genome-wide studies have revealed that mRNA localization is more widely utilized than previously thought to control gene expression. Not only can transcripts be localized asymmetrically within the cytoplasm, they are often also localized to symmetrically-distributed organelles. Recent genetic, cytological, and biochemical studies have begun to provide molecular insight into how cells select RNAs for transport, move them to specific destinations, and control their translation. This review will summarize recent insights into the mechanisms and function of RNA localization with a specific emphasis on molecular insights into each step in the mRNA localization process. PMID:23351709

  13. Localized neurofibromas in the bilateral orbits.

    PubMed

    Takeuchi, Satoru; Wada, Kojiro; Nagatani, Kimihiro; Nawashiro, Hiroshi

    2013-10-01

    Localized neurofibromas are rare in the orbit and, unlike the more common plexiform neurofibromas, are not typically associated with von Recklinghausen neurofibromatosis. We present a rare case of localized neurofibromas in the bilateral orbits. PMID:24426488

  14. The Local Group: Our Galactic Neighborhood.

    ERIC Educational Resources Information Center

    Hodge, Paul

    1987-01-01

    Presents information on the properties and largest spirals of the Local Group galaxies. Explains the three categories of galaxies, identifies the brightest members of the Local Group, and discusses recent discoveries within the group. (ML)

  15. Region effects influence local tree species diversity

    PubMed Central

    Ricklefs, Robert E.; He, Fangliang

    2016-01-01

    Global patterns of biodiversity reflect both regional and local processes, but the relative importance of local ecological limits to species coexistence, as influenced by the physical environment, in contrast to regional processes including species production, dispersal, and extinction, is poorly understood. Failure to distinguish regional influences from local effects has been due, in part, to sampling limitations at small scales, environmental heterogeneity within local or regional samples, and incomplete geographic sampling of species. Here, we use a global dataset comprising 47 forest plots to demonstrate significant region effects on diversity, beyond the influence of local climate, which together explain more than 92% of the global variation in local forest tree species richness. Significant region effects imply that large-scale processes shaping the regional diversity of forest trees exert influence down to the local scale, where they interact with local processes to determine the number of coexisting species. PMID:26733680

  16. Region effects influence local tree species diversity.

    PubMed

    Ricklefs, Robert E; He, Fangliang

    2016-01-19

    Global patterns of biodiversity reflect both regional and local processes, but the relative importance of local ecological limits to species coexistence, as influenced by the physical environment, in contrast to regional processes including species production, dispersal, and extinction, is poorly understood. Failure to distinguish regional influences from local effects has been due, in part, to sampling limitations at small scales, environmental heterogeneity within local or regional samples, and incomplete geographic sampling of species. Here, we use a global dataset comprising 47 forest plots to demonstrate significant region effects on diversity, beyond the influence of local climate, which together explain more than 92% of the global variation in local forest tree species richness. Significant region effects imply that large-scale processes shaping the regional diversity of forest trees exert influence down to the local scale, where they interact with local processes to determine the number of coexisting species. PMID:26733680

  17. Method for localizing heating in tumor tissue

    DOEpatents

    Doss, James D.; McCabe, Charles W.

    1977-04-12

    A method for a localized tissue heating of tumors is disclosed. Localized radio frequency current fields are produced with specific electrode configurations. Several electrode configurations are disclosed, enabling variations in electrical and thermal properties of tissues to be exploited.

  18. 32 CFR 1657.2 - Local boards.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... President. The Director shall prescribe the geographic jurisdiction of each board, and designate or... PROCESSING § 1657.2 Local boards. The Director shall establish local boards with jurisdiction to...

  19. Climate adaptation: Cultural knowledge and local risks

    NASA Astrophysics Data System (ADS)

    Strauss, Sarah

    2015-07-01

    A focus on African American communities on the Eastern Shore of Maryland highlights the ways that local cultural knowledge differs from place to place, developing understanding of local climate risks and resources for adaptation.

  20. Think Globally, Act Locally (Focus on Teaching).

    ERIC Educational Resources Information Center

    Vesper, Joan F.

    1994-01-01

    Describes a project, carried out jointly between a business communication class and a local chamber of commerce, that brings students into partnership with international merchants in the local community. (SR)

  1. 33 CFR 238.9 - Local cooperation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Local cooperation. 238.9 Section 238.9 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF... Local cooperation. (a) Cost sharing and other provisions of local cooperation shall be in...

  2. 33 CFR 238.9 - Local cooperation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Local cooperation. 238.9 Section 238.9 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF... Local cooperation. (a) Cost sharing and other provisions of local cooperation shall be in...

  3. 33 CFR 238.9 - Local cooperation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Local cooperation. 238.9 Section 238.9 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF... Local cooperation. (a) Cost sharing and other provisions of local cooperation shall be in...

  4. 33 CFR 238.9 - Local cooperation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Local cooperation. 238.9 Section 238.9 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF... Local cooperation. (a) Cost sharing and other provisions of local cooperation shall be in...

  5. 34 CFR 200.30 - Local review.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 1 2012-07-01 2012-07-01 false Local review. 200.30 Section 200.30 Education... Programs Operated by Local Educational Agencies Lea and School Improvement § 200.30 Local review. (a) Each... described in § 200.2 to review annually the progress of each school served under subpart A of this part...

  6. Closed locally minimal nets on tetrahedra

    SciTech Connect

    Strelkova, Nataliya P

    2011-01-31

    Closed locally minimal networks are in a sense a generalization of closed geodesics. A complete classification is known of closed locally minimal networks on regular (and generally any equihedral) tetrahedra. In the present paper certain necessary and certain sufficient conditions are given for at least one closed locally minimal network to exist on a given non-equihedral tetrahedron. Bibliography: 6 titles.

  7. 50 CFR 216.86 - Local regulations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 10 2012-10-01 2012-10-01 false Local regulations. 216.86 Section 216.86 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION... Pribilof Islands Administration § 216.86 Local regulations. Local regulations will be published from...

  8. 46 CFR 172.205 - Local damage.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Local damage. 172.205 Section 172.205 Shipping COAST... Subchapter O of This Chapter § 172.205 Local damage. (a) Each tankship must be shown by design calculations... operation assuming that local damage extending 30 inches (76 cm) normal to the hull shell is applied at...

  9. Local Observed-Score Kernel Equating

    ERIC Educational Resources Information Center

    Wiberg, Marie; van der Linden, Wim J.; von Davier, Alina A.

    2014-01-01

    Three local observed-score kernel equating methods that integrate methods from the local equating and kernel equating frameworks are proposed. The new methods were compared with their earlier counterparts with respect to such measures as bias--as defined by Lord's criterion of equity--and percent relative error. The local kernel item response…

  10. Local Government Uses of Cable Television.

    ERIC Educational Resources Information Center

    Cable Television Information Center, Washington, DC.

    The local government cable access channel is essentially a television station completely controlled by the local government. It differs from a local broadcast television station by being able to reach only those places which are connected to the cable system, having much less programming distribution costs, and having the capacity to deliver…

  11. Gaussianity and localization of N -qubit states

    NASA Astrophysics Data System (ADS)

    Gaeta, M.; Muñoz, C.; Klimov, A. B.

    2016-06-01

    We analyze collective properties of N -qubit states. In particular, we exhaustively discuss the localization aspect of distributions in the measurement space and introduce the concept of Gaussian states in the macroscopic limit. The effect of local shifts on the localization and Gaussianity is analyzed.

  12. Localism: The Changing Picture for Adult Learning

    ERIC Educational Resources Information Center

    Lamb, Penny

    2012-01-01

    The rapidly changing picture on localism and the government's focus on local economic growth have significant implications for adult learning and skills providers in England. Government now sees a sense of place as key to economic growth and recognises the need for a renewed debate on how business and state interact with localities. There is a…

  13. Local Service Learning in Teacher Preparation Program

    ERIC Educational Resources Information Center

    Nuangchalerm, Prasart

    2016-01-01

    The local knowledge is simply integrated in education and learning process. This study aims to promote local knowledge in school through service learning. The learning process is employed herbal plants to reinforce students learn how to sustain local knowledge with modern life and 21st century classroom. Participants consisted of 42 pre-service…

  14. Diverse Local Literacies and Standardizing Policies

    ERIC Educational Resources Information Center

    Bomer, Randy; Maloch, Beth

    2012-01-01

    The authors challenge educators to speculate on how to address local issues in a world that is increasingly diverse and global. This Research and Policy section emphasizes the seemingly paradoxical importance of both local and global literacy, illuminating the tension between the preservation of local literacy and a global standardization of…

  15. Localization: A Career for the New Millennium

    ERIC Educational Resources Information Center

    Gibbs, Hope J.

    2004-01-01

    Founded in 2000, the Localization Generalist Certificate Program at Austin Community College (ACC) was the recipient of the 2004 ClientSide Excellence Award in the category of Localization Educational Services. It is the only community college program of its kind and one of only a handful of programs worldwide. What is localization and why is it…

  16. 2 CFR 25.340 - Local government.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Local government. 25.340 Section 25.340... IDENTIFIER AND CENTRAL CONTRACTOR REGISTRATION Definitions § 25.340 Local government. Local government means...; (i) Special district; (j) School district; (k) Intrastate district; (l) Council of...

  17. 2 CFR 25.340 - Local government.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Local government. 25.340 Section 25.340... CENTRAL CONTRACTOR REGISTRATION Definitions § 25.340 Local government. Local government means a: (a... district; (j) School district; (k) Intrastate district; (l) Council of governments, whether or...

  18. 2 CFR 200.64 - Local government.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Local government. 200.64 Section 200.64... REQUIREMENTS FOR FEDERAL AWARDS Acronyms and Definitions Acronyms § 200.64 Local government. Local government means any unit of government within a state, including a: (a) County; (b) Borough; (c) Municipality;...

  19. 2 CFR 25.340 - Local government.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 2 Grants and Agreements 1 2012-01-01 2012-01-01 false Local government. 25.340 Section 25.340... IDENTIFIER AND CENTRAL CONTRACTOR REGISTRATION Definitions § 25.340 Local government. Local government means...; (i) Special district; (j) School district; (k) Intrastate district; (l) Council of...

  20. Art and Place: The Local Connection.

    ERIC Educational Resources Information Center

    Van Dyke, Jan

    1999-01-01

    Stresses the importance of local arts, focusing on encouraging modern dance at the local level. Addresses issues such as audience participation, sense of ownership and community, and accessibility that accompanies local art. Considers the implications for K-12 modern dance education. (CMK)

  1. Colleges Chew on Local-Food Phenomenon

    ERIC Educational Resources Information Center

    Carlson, Scott

    2008-01-01

    Nationally, students have pushed hard for local-food programs, and the amount of local produce in the dining hall is sometimes used as a litmus test for a college's overall commitment to sustainability. Local food has been a hot topic in popular culture in recent years, thanks in part to books by Michael Pollan and Barbara Kingsolver, movies like…

  2. 10 CFR 440.13 - Local applications.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Local applications. 440.13 Section 440.13 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION WEATHERIZATION ASSISTANCE FOR LOW-INCOME PERSONS § 440.13 Local applications. (a) The Support Office Director shall give written notice to all local applicants throughout...

  3. 10 CFR 440.13 - Local applications.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Local applications. 440.13 Section 440.13 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION WEATHERIZATION ASSISTANCE FOR LOW-INCOME PERSONS § 440.13 Local applications. (a) The Support Office Director shall give written notice to all local applicants throughout...

  4. Huave de San Mateo del Mar, Oaxaca (Huave of San Mateo del Mar, Oaxaca).

    ERIC Educational Resources Information Center

    Mexico Coll. (Mexico City)

    This document is one of 17 volumes on indigenous Mexican languages and is the result of a project undertaken by the Archivo de Lenguas Indigenas de Mexico. This volume contains information on Huave, an indigenous language of Mexico spoken in San Mateo del Mar, in the state of Oaxaca. The objective of collecting such a representative sampling of…

  5. The local dark matter density

    NASA Astrophysics Data System (ADS)

    Read, J. I.

    2014-06-01

    I review current efforts to measure the mean density of dark matter near the Sun. This encodes valuable dynamical information about our Galaxy and is also of great importance for ‘direct detection’ dark matter experiments. I discuss theoretical expectations in our current cosmology; the theory behind mass modelling of the Galaxy; and I show how combining local and global measures probes the shape of the Milky Way dark matter halo and the possible presence of a ‘dark disc’. I stress the strengths and weaknesses of different methodologies and highlight the continuing need for detailed tests on mock data—particularly in the light of recently discovered evidence for disequilibria in the Milky Way disc. I collate the latest measurements of ρdm and show that, once the baryonic surface density contribution Σb is normalized across different groups, there is remarkably good agreement. Compiling data from the literature, I estimate Σb = 54.2 ± 4.9 M⊙pc-2, where the dominant source of uncertainty is in the H i gas contribution. Assuming this contribution from the baryons, I highlight several recent measurements of ρdm in order of increasing data complexity and prior, and, correspondingly, decreasing formal error bars. Comparing these measurements with spherical extrapolations from the Milky Way’s rotation curve, I show that the Milky Way is consistent with having a spherical dark matter halo at R0 ˜ 8 kpc. The very latest measures of ρdm based on ˜10 000 stars from the Sloan Digital Sky Survey appear to favour little halo flattening at R0, suggesting that the Galaxy has a rather weak dark matter disc, with a correspondingly quiescent merger history. I caution, however, that this result hinges on there being no large systematics that remain to be uncovered in the SDSS data, and on the local baryonic surface density being Σb ˜ 55 M⊙pc-2. I conclude by discussing how the new Gaia satellite will be transformative. We will obtain much tighter

  6. Atom localization with double-cascade configuration

    NASA Astrophysics Data System (ADS)

    Gordeev, Maksim Yu; Efremova, Ekaterina A.; Rozhdestvensky, Yuri V.

    2016-03-01

    We investigate the one-dimensional (1D) and two-dimensional (2D) atom localization of a four-level system in a double-cascade configuration. We demonstrate the possibility of 1D localization in the field of a standing wave, 2D localization in the field of two standing waves and 2D localization only in the field of running waves by using different configurations of driven waves on transitions. In addition, for each configuration we reached a high-precision atom localization in one of the states at scales much smaller than the wavelength of the incident optical radiation.

  7. Texture classification by local rank correlation

    NASA Technical Reports Server (NTRS)

    Harwood, D.; Subbarao, M.; Davis, L. S.

    1985-01-01

    A new approach to texture classification based on local rank correlation is proposed here. Its performance is compared with Laws' method which uses local convolution with feature masks. In the experiments, texture samples are classified based on their distribution of local statistics, either rank correlations or convolutions. The new method achieves generally optimal classification rates. It appears to be more robust because local order statistics are unaffected by local sample differences due to monotonic shifts of texture gray values and are less sensitive to noise.

  8. Increased localization precision by interference fringe analysis.

    PubMed

    Ebeling, Carl G; Meiri, Amihai; Martineau, Jason; Zalevsky, Zeev; Gerton, Jordan M; Menon, Rajesh

    2015-06-21

    We report a novel optical single-emitter-localization methodology that uses the phase induced by path length differences in a Mach-Zehnder interferometer to improve localization precision. Using information theory, we demonstrate that the localization capability of a modified Fourier domain signal generated by photon interference enables a more precise localization compared to a standard Gaussian intensity distribution of the corresponding point-spread function. The calculations were verified by numerical simulations and an exemplary experiment, where the centers of metal nanoparticles were localized to a precision of 3 nm. PMID:25999093

  9. Cannabinoid receptor localization in brain

    SciTech Connect

    Herkenham, M.; Lynn, A.B.; Little, M.D.; Johnson, M.R.; Melvin, L.S.; de Costa, B.R.; Rice, K.C. )

    1990-03-01

    (3H)CP 55,940, a radiolabeled synthetic cannabinoid, which is 10-100 times more potent in vivo than delta 9-tetrahydrocannabinol, was used to characterize and localize a specific cannabinoid receptor in brain sections. The potencies of a series of natural and synthetic cannabinoids as competitors of (3H)CP 55,940 binding correlated closely with their relative potencies in several biological assays, suggesting that the receptor characterized in our in vitro assay is the same receptor that mediates behavioral and pharmacological effects of cannabinoids, including human subjective experience. Autoradiography of cannabinoid receptors in brain sections from several mammalian species, including human, reveals a unique and conserved distribution; binding is most dense in outflow nuclei of the basal ganglia--the substantia nigra pars reticulata and globus pallidus--and in the hippocampus and cerebellum. Generally high densities in forebrain and cerebellum implicate roles for cannabinoids in cognition and movement. Sparse densities in lower brainstem areas controlling cardiovascular and respiratory functions may explain why high doses of delta 9-tetrahydrocannabinol are not lethal.

  10. Active localization of virtual sounds

    NASA Astrophysics Data System (ADS)

    Loomis, Jack M.; Hebert, C.; Cicinelli, J. G.

    1991-06-01

    We describe a virtual sound display built around a 12 MHz 80286 microcomputer and special purpose analog hardware. The display implements most of the primary cues for sound localization in the ear-level plane. Static information about direction is conveyed by interaural time differences and, for frequencies above 1800 Hz, by head sound shadow (interaural intensity differences) and pinna sound shadow. Static information about distance is conveyed by variation in sound pressure (first power law) for all frequencies, by additional attenuation in the higher frequencies (simulating atmospheric absorption), and by the proportion of direct to reverberant sound. When the user actively locomotes, the changing angular position of the source occasioned by head rotations provides further information about direction and the changing angular velocity produced by head translations (motion parallax) provides further information about distance. Judging both from informal observations by users and from objective data obtained in an experiment on homing to virtual and real sounds, we conclude that simple displays such as this are effective in creating the perception of external sounds to which subjects can home with accuracy and ease.

  11. Localized structures in gaseous combustion

    NASA Astrophysics Data System (ADS)

    Knobloch, Edgar; Lo Jacono, David; Bergeon, Alain

    2015-11-01

    We consider a flame between a pair of porous walls at x = +/- 1 that allow fuel and oxidizer to diffuse into the burn region from opposite sides. The burn process is described by a binary one-step process of Arrhenius type. The heat released is redistributed via radiation. Convection is ignored. In 1D the low and high temperature states are connected by an S-shaped branch with a fold at low Damköhler number below which extinction takes place. Various instabilities occur on the upper (flame) branch leading to different time-dependent but 1D flames. In 2D the situation is dramatically modified: near the extinction region the burn front breaks up into structures that are localized in the direction along the front, with multiple branches of such states bifurcating from the fold. These correspond to states with n = 1 , 2 , ⋯ identical and equispaced hotspots. Further bifurcations generate states in which the hotspots are nonidentical and separated by unequal distances. All these states are present in the same parameter interval, implying great sensitivity of the system to initial conditions.

  12. Intrinsic Localized Modes in Proteins

    PubMed Central

    Nicolaï, Adrien; Delarue, Patrice; Senet, Patrick

    2015-01-01

    Protein dynamics is essential for proteins to function. Here we predicted the existence of rare, large nonlinear excitations, termed intrinsic localized modes (ILMs), of the main chain of proteins based on all-atom molecular dynamics simulations of two fast-folder proteins and of a rigid α/β protein at 300 K and at 380 K in solution. These nonlinear excitations arise from the anharmonicity of the protein dynamics. The ILMs were detected by computing the Shannon entropy of the protein main-chain fluctuations. In the non-native state (significantly explored at 380 K), the probability of their excitation was increased by a factor between 9 and 28 for the fast-folder proteins and by a factor 2 for the rigid protein. This enhancement in the non-native state was due to glycine, as demonstrated by simulations in which glycine was mutated to alanine. These ILMs might play a functional role in the flexible regions of proteins and in proteins in a non-native state (i.e. misfolded or unfolded states). PMID:26658321

  13. Improved Measure of Local Chirality

    SciTech Connect

    Terrence Draper; Andrei Alexandru; Ying Chen; Shao-Jing Dong; Ivan Horvath; Frank Lee; Nilmani Mathur; Harry B. Thacker; Sonali Tamhankar; Jianbo Zhang

    2004-06-01

    It is popular to probe the structure of the QCD vacuum indirectly by studying individual fermion eigenmodes, because this provides a natural way to filter out UV fluctuations. The double-peaking in the distribution of the local chiral orientation parameter (X) has been offered as evidence, by some, in support of a particular model of the vacuum. Here we caution that the X-distribution peaking varies significantly with various versions of the definition of X. Furthermore, each distribution varies little from that resulting from a random reshuffling of the left-handed (and independently the right-handed) fields, which destroys any QCD-induced left-right correlation; that is, the double-peaking is mostly a phase-space effect. We propose a new universal definition of the X parameter whose distribution is uniform for randomly reshuffled fields. Any deviations from uniformity for actual data can then be directly attributable to QCD-induced dynamics. We find that the familiar double peak disappears.

  14. Study of PTEN subcellular localization

    PubMed Central

    Bononi, Angela; Pinton, Paolo

    2015-01-01

    The tumor suppressor PTEN is a key regulator of a plethora of cellular processes that are crucial in cancer development. Through its lipid phosphatase activity PTEN suppresses the PI3K/AKT pathway to govern cell proliferation, growth, migration, energy metabolism and death. The repertoire of roles fulfilled by PTEN has recently been expanded to include crucial functions in the nucleus, where it favors genomic stability and restrains cell cycle progression, as well as protein phosphatase dependent activity at the endoplasmic reticulum (ER) and mitochondria-associated membranes (MAMs), where PTEN interacts with the inositol 1,4,5-trisphosphate receptors (IP3Rs) and regulates Ca2+ release from the ER and sensitivity to apoptosis. Indeed, PTEN is present in definite subcellular locations where it performs distinct functions acting on specific effectors. In this review, we summarize recent advantages in methods to study PTEN subcellular localization and the distinct biological functions of PTEN in different cellular compartments. A deeper understanding of PTEN’s compartmentalized-functions will guide the rational design of novel therapies. PMID:25312582

  15. Macroecology of local insect communities

    NASA Astrophysics Data System (ADS)

    Krüger, Oliver; McGavin, George C.

    2000-01-01

    The inter-relationships between animal body weight, range size, species richness and abundance are currently the basis of macroecology. Using 41 099 insects sampled from 31 Acacia tree canopies in north-east Tanzania, we first documented the basic macroecological patterns. The relationship between body weight and both species richness and abundance was polygonal with the highest insect species richness and abundance occurring at intermediate body weights. Across individual tree communities, the most statistically robust relationships were found between range size, abundance and species richness and they were all linear. In a second part, we focused on the positive abundance-range size relationship and we could test predictions of six of the eight proposed hypotheses to explain this widely documented pattern of community structure. The relationship is most likely explained by the metapopulation hypothesis stating that with more patches being occupied, local abundance in a given patch increases due to a higher rate of immigration from nearby patches. In addition, we found high slopes for the species-area relationship, typical of island systems and thus it seems reasonable to characterise Acacia trees in the savannah as habitat islands for insects.

  16. Coordinating locally 'owned' treatment guidelines.

    PubMed

    Collier, J; Picton, C; Littlejohns, P

    1994-01-01

    South West Thames Regional Health Authority established and commissioned a regional guidelines unit to coordinate the introduction of a set of treatment guidelines on the management of common medical emergencies into all the acute intaking National Health Service (NHS) hospitals throughout the region. All hospitals were offered a set of template guidelines to be used at their discretion for producing their own customised equivalent. They were also offered full typing and production facilities, together with printing costs if publication was achieved by a target deadline (1 August 1993). In 11 of the 14 NHS hospitals guidelines were available to hospital staff by the target deadline, and one set was produced for a non-NHS hospital. In two hospitals the target date was not met, and one other declined to take part. As part of the project the unit assessed the extent to which the published guidelines were adapted to meet the requirements of each individual hospital. The template offered guidelines on 34 topic titles. No hospital used all core titles of the original template; titles were omitted or replaced in some, and added in others. Where the original guideline titles were used, there was almost always some customisation--changes in sentence structure, names or contact numbers, alterations in drugs and doses or the addition or omission of entire sections. By using an established resource, sets of customised, locally determined treatment guidelines were introduced with relative ease into most of the acute hospitals in a UK health region. PMID:7884707

  17. Global versus local adsorption selectivity

    NASA Astrophysics Data System (ADS)

    Pauzat, Françoise; Marloie, Gael; Markovits, Alexis; Ellinger, Yves

    2015-10-01

    The origin of the enantiomeric excess found in the amino acids present in the organic matter of carbonaceous meteorites is still unclear. Selective adsorption of one of the two enantiomers existing after a racemic formation could be part of the answer. Hereafter we report a comparative study of the adsorption of the R and S enantiomers of α-alanine and lactic acid on the hydroxylated { } chiral surface of α-quartz using numerical simulation techniques. Structurally different adsorption sites were found with opposite R versus S selectivity for the same molecule-surface couple, raising the problem of whether to consider adsorption as a local property or as a global response characteristic of the whole surface. To deal with the second term of this alternative, a statistical approach was designed, based on the occurrence of each adsorption site whose energy was calculated using first principle periodic density functional theory. It was found that R-alanine and S-lactic acid are the enantiomers preferentially adsorbed, even if the adsorption process on the quartz { } surface stays with a disappointingly poor enantio-selectivity. Nevertheless, it highlighted the important point that considering adsorption as a global property changes perspectives in the search for more efficient enantio-selective supports and more generally changes the way to apprehend adsorption processes in astro-chemistry/biology.

  18. Intrinsic Localized Modes in Proteins.

    PubMed

    Nicolaï, Adrien; Delarue, Patrice; Senet, Patrick

    2015-01-01

    Protein dynamics is essential for proteins to function. Here we predicted the existence of rare, large nonlinear excitations, termed intrinsic localized modes (ILMs), of the main chain of proteins based on all-atom molecular dynamics simulations of two fast-folder proteins and of a rigid α/β protein at 300 K and at 380 K in solution. These nonlinear excitations arise from the anharmonicity of the protein dynamics. The ILMs were detected by computing the Shannon entropy of the protein main-chain fluctuations. In the non-native state (significantly explored at 380 K), the probability of their excitation was increased by a factor between 9 and 28 for the fast-folder proteins and by a factor 2 for the rigid protein. This enhancement in the non-native state was due to glycine, as demonstrated by simulations in which glycine was mutated to alanine. These ILMs might play a functional role in the flexible regions of proteins and in proteins in a non-native state (i.e. misfolded or unfolded states). PMID:26658321

  19. Active localization of virtual sounds

    NASA Technical Reports Server (NTRS)

    Loomis, Jack M.; Hebert, C.; Cicinelli, J. G.

    1991-01-01

    We describe a virtual sound display built around a 12 MHz 80286 microcomputer and special purpose analog hardware. The display implements most of the primary cues for sound localization in the ear-level plane. Static information about direction is conveyed by interaural time differences and, for frequencies above 1800 Hz, by head sound shadow (interaural intensity differences) and pinna sound shadow. Static information about distance is conveyed by variation in sound pressure (first power law) for all frequencies, by additional attenuation in the higher frequencies (simulating atmospheric absorption), and by the proportion of direct to reverberant sound. When the user actively locomotes, the changing angular position of the source occasioned by head rotations provides further information about direction and the changing angular velocity produced by head translations (motion parallax) provides further information about distance. Judging both from informal observations by users and from objective data obtained in an experiment on homing to virtual and real sounds, we conclude that simple displays such as this are effective in creating the perception of external sounds to which subjects can home with accuracy and ease.

  20. Segmentation in local hospital markets.

    PubMed

    Dranove, D; White, W D; Wu, L

    1993-01-01

    This study examines evidence of market segmentation on the basis of patients' insurance status, demographic characteristics, and medical condition in selected local markets in California in the years 1983 and 1989. Substantial differences exist in the probability patients may be admitted to particular hospitals based on insurance coverage, particularly Medicaid, and race. Segmentation based on insurance and race is related to hospital characteristics, but not the characteristics of the hospital's community. Medicaid patients are more likely to go to hospitals with lower costs and fewer service offerings. Privately insured patients go to hospitals offering more services, although cost concerns are increasing. Hispanic patients also go to low-cost hospitals, ceteris paribus. Results indicate little evidence of segmentation based on medical condition in either 1983 or 1989, suggesting that "centers of excellence" have yet to play an important role in patient choice of hospital. The authors found that distance matters, and that patients prefer nearby hospitals, moreso for some medical conditions than others, in ways consistent with economic theories of consumer choice. PMID:8417270

  1. Local earthquake tomography of Scotland

    NASA Astrophysics Data System (ADS)

    Luckett, Richard; Baptie, Brian

    2015-03-01

    Scotland is a relatively aseismic region for the use of local earthquake tomography, but 40 yr of earthquakes recorded by a good and growing network make it possible. A careful selection is made from the earthquakes located by the British Geological Survey (BGS) over the last four decades to provide a data set maximising arrival time accuracy and ray path coverage of Scotland. A large number of 1-D velocity models with different layer geometries are considered and differentiated by employing quarry blasts as ground-truth events. Then, SIMULPS14 is used to produce a robust 3-D tomographic P-wave velocity model for Scotland. In areas of high resolution the model shows good agreement with previously published interpretations of seismic refraction and reflection experiments. However, the model shows relatively little lateral variation in seismic velocity except at shallow depths, where sedimentary basins such as the Midland Valley are apparent. At greater depths, higher velocities in the northwest parts of the model suggest that the thickness of crust increases towards the south and east. This observation is also in agreement with previous studies. Quarry blasts used as ground truth events and relocated with the preferred 3-D model are shown to be markedly more accurate than when located with the existing BGS 1-D velocity model.

  2. Local excision for selected colorectal carcinomas.

    PubMed

    Lawrence, M A; Goldberg, S M

    1989-07-01

    In summary, local excision is a useful tool in the management of selected colorectal carcinomas. The advent of the fibreoptic colonoscope has revised the concept of local excision when dealing with carcinoma-containing polyps of the colon. The clinician now has the means of locally excising certain carcinomas which would have required laparotomy in the not so distant past. In dealing with carcinoma of the rectum, local excision is not advocated for all rectal carcinomas. In fact, when the previously discussed tumour related factors are considered, local excision should be the ultimate procedure in less than 5% of operations performed for rectal carcinomas. However, when appropriately used, local excision provides a less morbid alternative to more radical procedures without compromising patient survival rates or local recurrence rates. PMID:2692739

  3. Instantánea del sarcoma de Kaposi

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el sarcoma de Kaposi; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  4. Pastoral del Nino: Bringing the Abundant Life to Paraguayan Children

    ERIC Educational Resources Information Center

    Austin, Ann Berghout; Aquino, Cyle; Burro, Elizabeth

    2007-01-01

    Pastoral del Nino is transforming children's lives in rural Paraguay. Part of Pastoral Social (Catholic Social Services), Pastoral del Nino's primary focus is to bring "vida en abundancia" (the abundant life) to families by ensuring that mothers survive childbirth and children reach their first birthdays. In addition, the organization promotes…

  5. 75 FR 11104 - Del Norte Resource Advisory Committee (RAC)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... Forest Service Del Norte Resource Advisory Committee (RAC) AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Del Norte Resource Advisory Committee (RAC) will meet in Crescent City... and Designated Federal Official roles and (5) review operational guidelines; (6) selection of...

  6. Research and Evaluation Within the Del Mod System.

    ERIC Educational Resources Information Center

    Bolig, John R.

    Described is the Del Mod System, its inception, the fundings associated with it, and its objectives. A number of projects have already been completed and implemented. This monograph describes the evaluations of such projects and of the Del Mod systems-approach to science education. The area of evaluation and the method of data collection (with…

  7. 33 CFR 80.1118 - Marina Del Rey, CA.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Marina Del Rey, CA. 80.1118 Section 80.1118 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Coast § 80.1118 Marina Del Rey, CA. (a) A line drawn...

  8. Instantánea del cáncer colorrectal

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer colorrectal; así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  9. Correlation of EGFR Del 19 with Fn14/JAK/STAT signaling molecules in non-small cell lung cancer.

    PubMed

    Sun, Ying; Han, Yong; Wang, Xiaoping; Wang, Wuping; Wang, Xuejiao; Wen, Miaomiao; Xia, Jinghua; Xing, Hao; Li, Xiaofei; Zhang, Zhipei

    2016-08-01

    Previous research has shown that p-EGFR (particularly mutated EGFR) may activate fibroblast growth factor-inducible 14 (Fn14) expression in non-small cell lung cancer (NSCLC), and the JAK/STAT signaling pathway may participate in this process. Thus, in order to verify this hypothesis, correlations among the expression levels of EGFR Del 19, Fn14 and JAK/STAT were detected and analyzed. The expression and location of these molecules were assessed using IHC, immunohistofluorescence, RT-qPCR and western blotting. The differences and correlations in the expression of these molecules and clinical pathological characteristics were statistically analyzed using Mann-Whitney U, Kruskal‑Wallis H and cross-table tests. Kaplan-Meier survival analysis and Cox proportional hazards models were used to estimate the effect of EGFR Del 19 and Fn14 expression on survival. Data showed that EGFR Del 19, Fn14 and JAK1/STAT1 expression was significantly related with differentiation, pTNM stage and lymphatic metastasis (P<0.01) and there was a marked correlation of EGFR Del 19, Fn14 and JAK1/STAT1 expression with histological type, differentiation, pTNM stage of NSCLC (P<0.05; rs>0.3). Immunohistofluorescence showed that there was a co-localization phenomenon between EGFR Del 19 and Fn14 expression. NSCLC patients with higher EGFR Del 19/Fn14 expression had a significantly worse prognosis than those with lower EGFR Del 19/Fn14 expression (P=0.0155/P=0.001; log-rank test). The multivariate analysis indicated that Fn14 expression may be an independent prognostic factor in NSCLC with EGFR Del 19 [hazard ratio (HR), 0.326; P=0.042]. Therefore, our results indicate that EGFR Del 19 may promote Fn14 and JAK1/STAT1 expression in NSCLC and Fn14 may serve as a prognostic biomarker in NSCLC with EGFR Del 19. PMID:27350337

  10. When Gravity Fails: Local Search Topology

    NASA Technical Reports Server (NTRS)

    Frank, Jeremy; Cheeseman, Peter; Stutz, John; Lau, Sonie (Technical Monitor)

    1997-01-01

    Local search algorithms for combinatorial search problems frequently encounter a sequence of states in which it is impossible to improve the value of the objective function; moves through these regions, called {\\em plateau moves), dominate the time spent in local search. We analyze and characterize {\\em plateaus) for three different classes of randomly generated Boolean Satisfiability problems. We identify several interesting features of plateaus that impact the performance of local search algorithms. We show that local minima tend to be small but occasionally may be very large. We also show that local minima can be escaped without unsatisfying a large number of clauses, but that systematically searching for an escape route may be computationally expensive if the local minimum is large. We show that plateaus with exits, called benches, tend to be much larger than minima, and that some benches have very few exit states which local search can use to escape. We show that the solutions (i.e. global minima) of randomly generated problem instances form clusters, which behave similarly to local minima. We revisit several enhancements of local search algorithms and explain their performance in light of our results. Finally we discuss strategies for creating the next generation of local search algorithms.

  11. On the concept of Bell’s local causality in local classical and quantum theory

    SciTech Connect

    Hofer-Szabó, Gábor; Vecsernyés, Péter

    2015-03-15

    The aim of this paper is to implement Bell’s notion of local causality into a framework, called local physical theory. This framework, based on the axioms of algebraic field theory, is broad enough to integrate both probabilistic and spatiotemporal concepts and also classical and quantum theories. Bell’s original idea of local causality will arise as the classical case of our definition. Classifying local physical theories by whether they obey local primitive causality, a property rendering the dynamics of the theory causal, we then investigate what is needed for a local physical theory to be locally causal. Finally, comparing local causality with the common cause principles and relating both to the Bell inequalities we find a nice parallelism: Bell inequalities cannot be derived neither from local causality nor from a common cause unless the local physical theory is classical or the common cause is commuting, respectively.

  12. Predicting Nonspecific Ion Binding Using DelPhi

    PubMed Central

    Petukh, Marharyta; Zhenirovskyy, Maxim; Li, Chuan; Li, Lin; Wang, Lin; Alexov, Emil

    2012-01-01

    Ions are an important component of the cell and affect the corresponding biological macromolecules either via direct binding or as a screening ion cloud. Although some ion binding is highly specific and frequently associated with the function of the macromolecule, other ions bind to the protein surface nonspecifically, presumably because the electrostatic attraction is strong enough to immobilize them. Here, we test such a scenario and demonstrate that experimentally identified surface-bound ions are located at a potential that facilitates binding, which indicates that the major driving force is the electrostatics. Without taking into consideration geometrical factors and structural fluctuations, we show that ions tend to be bound onto the protein surface at positions with strong potential but with polarity opposite to that of the ion. This observation is used to develop a method that uses a DelPhi-calculated potential map in conjunction with an in-house-developed clustering algorithm to predict nonspecific ion-binding sites. Although this approach distinguishes only the polarity of the ions, and not their chemical nature, it can predict nonspecific binding of positively or negatively charged ions with acceptable accuracy. One can use the predictions in the Poisson-Boltzmann approach by placing explicit ions in the predicted positions, which in turn will reduce the magnitude of the local potential and extend the limits of the Poisson-Boltzmann equation. In addition, one can use this approach to place the desired number of ions before conducting molecular-dynamics simulations to neutralize the net charge of the protein, because it was shown to perform better than standard screened Coulomb canned routines, or to predict ion-binding sites in proteins. This latter is especially true for proteins that are involved in ion transport, because such ions are loosely bound and very difficult to detect experimentally. PMID:22735539

  13. A new iterative Chebyshev spectral method for solving the elliptic equation [del] [center dot] ([sigma] [del]u) = f

    SciTech Connect

    Zhao, Shengkai; Yedlin, M.J. )

    1994-08-01

    We present a new iterative Chebyshev spectral method for solving the elliptic equation [del] [center dot] ([sigma] [del]u) = f. We rewrite the equation in the form of a Poisson's equation [del][sup 2]u = (f - [del]u [center dot] [del][sigma]/[sigma]). In each iteration we compute the right-hand side terms from the guess values first. Then we solve the resultant Poisson equation by a direct method to obtain the updated values. Three numerical examples are presented. For the sam number of iterations, the accuracy of the present method is about 6-8 orders better than the Chebyshev spectral multigrid method. On a SPARC Station 2 computer, the CPU time of the new method is about one-third of the Chebyshev spectral multigrid method. To obtain the same accuracy, the CPU time of the present method is about one-tenth of the Chebyshev spectral multigrid method. 17 refs., 5 figs., 3 tabs.

  14. NMR local coil with adjustable spacing

    SciTech Connect

    Dembinski, G.T.

    1988-03-22

    A local coil assembly for use in NMR imaging is described which comprises: a base; a first local coil module mounted to the base and extending upward therefrom; sockets disposed in the base, each at a different distance from the first local coil module; a second local coil module having a connector therein which mates with each of the sockets to enable the second local coil module to be connected to the base at any one of the sockets; and a set of reactive components. The values of the respective reactive components are selected such that the second local oil module may be connected to any of the sockets without any substantial change in the resonant frequency of the assembly.

  15. Mobile Sensor Network Localization in Harsh Environments

    NASA Astrophysics Data System (ADS)

    Chenji, Harsha; Stoleru, Radu

    The node localization problem in mobile sensor networks has recently received significant attention. Particle filters, adapted from robotics, have produced good localization accuracies in conventional settings, but suffer significantly when used in challenging indoor and mobile environments characterized by a high degree of radio irregularity. We propose FuzLoc, a fuzzy logic-based approach for mobile node localization in challenging environments and formulate the localization problem as a fuzzy multilateration problem, with a fuzzy grid-prediction scheme for sparse networks. We demonstrate the performance and feasibility of our localization scheme through extensive simulations and a proof-of-concept implementation on hardware, respectively. Simulation results augmented by data gathered from our 42 node indoor testbed demonstrate improvements in the localization accuracy from 20%-40% when the radio irregularity is high.

  16. How ambiguous is the local kinetic energy?

    PubMed

    Anderson, James S M; Ayers, Paul W; Hernandez, Juan I Rodriguez

    2010-08-26

    The local kinetic energy and the closely related local electronic stress tensor are commonly used to elucidate chemical bonding patterns, especially for covalent bonds. We use three different approaches-transformation properties of the stress tensor, quasiprobability distributions, and the virial theorem from density-functional theory-to clarify the inherent ambiguity in these quantities, discussing the implications for analyses based on the local kinetic energy and stress tensor. An expansive-but not universal-family of local kinetic energy forms that includes the most common choices and is suitable for both chemical-bonding and atoms-in-molecule analysis is derived. A family of local electronic stress tensors is also derived. Several local kinetic energy functions that are mathematically justified, but unlikely to be conceptually useful, are derived. The implications of these forms for atoms-in-molecule analysis are discussed. PMID:20586467

  17. Fully localized two-dimensional embedded solitons

    SciTech Connect

    Yang Jianke

    2010-11-15

    We report the prediction of fully localized two-dimensional embedded solitons. These solitons are obtained in a quasi-one-dimensional waveguide array which is periodic along one spatial direction and localized along the orthogonal direction. Under appropriate nonlinearity, these solitons are found to exist inside the Bloch bands (continuous spectrum) of the waveguide and thus are embedded solitons. These embedded solitons are fully localized along both spatial directions. In addition, they are fully stable under perturbations.

  18. Methods and strategies of object localization

    NASA Technical Reports Server (NTRS)

    Shao, Lejun; Volz, Richard A.

    1989-01-01

    An important property of an intelligent robot is to be able to determine the location of an object in 3-D space. A general object localization system structure is proposed, some important issues on localization discussed, and an overview given for current available object localization algorithms and systems. The algorithms reviewed are characterized by their feature extracting and matching strategies; the range finding methods; the types of locatable objects; and the mathematical formulating methods.

  19. A Local Approach to Hybrid Data Assimilation

    NASA Astrophysics Data System (ADS)

    Ide, K.; Kleist, D. T.

    2014-12-01

    A hybrid system with the local formulation is developed where the prior probability density function (pdf) consists of both statistical and dynamic information of the uncertainty. The dynamic information is provided by the monte caro approach. The local formulation is solved at every grid as in the local ensemble transform Kalman filter. The formulation is flexible in that it allows not only Gaussian but other stable pdfs.

  20. Local quanta, unitary inequivalence, and vacuum entanglement

    SciTech Connect

    Vázquez, Matías R. Rey, Marco del Westman, Hans León, Juan

    2014-12-15

    In this work we develop a formalism for describing localised quanta for a real-valued Klein–Gordon field in a one-dimensional box [0,R]. We quantise the field using non-stationary local modes which, at some arbitrarily chosen initial time, are completely localised within the left or the right side of the box. In this concrete set-up we directly face the problems inherent to a notion of local field excitations, usually thought of as elementary particles. Specifically, by computing the Bogoliubov coefficients relating local and standard (global) quantisations, we show that the local quantisation yields a Fock representation of the Canonical Commutation Relations (CCR) which is unitarily inequivalent to the standard one. In spite of this, we find that the local creators and annihilators remain well defined in the global Fock space F{sup G}, and so do the local number operators associated to the left and right partitions of the box. We end up with a useful mathematical toolbox to analyse and characterise local features of quantum states in F{sup G}. Specifically, an analysis of the global vacuum state |0{sub G}〉∈F{sup G} in terms of local number operators shows, as expected, the existence of entanglement between the left and right regions of the box. The local vacuum |0{sub L}〉∈F{sup L}, on the contrary, has a very different character. It is neither cyclic (with respect to any local algebra of operators) nor separating and displays no entanglement between left and right partitions. Further analysis shows that the global vacuum also exhibits a distribution of local excitations reminiscent, in some respects, of a thermal bath. We discuss how the mathematical tools developed herein may open new ways for the analysis of fundamental problems in local quantum field theory.

  1. THE LOCAL LIMIT OF GLOBAL GYROKINETIC SIMULATIONS

    SciTech Connect

    CANDY J; WALTZ RE; DORLAND W

    2003-10-01

    OAK-B135 Global gyrokinetic simulations of turbulence include physical effects that are not retained in local flux-tube simulations. nevertheless, in the limit of sufficiently small {rho}* (gyroradius compared to system size) it is expected that a local simulation should agree with a global one (at the local simulation radius) since all effects that are dropped in the local simulations are expected to vanish as {rho}* {yields} 0. In this note, global simulations of a well-established test case are indeed shown to recover the flux-tube limit at each radius.

  2. Angular momentum in the Local Group

    SciTech Connect

    Dunn, A.; Laflamme, R.

    1994-04-01

    We briefly review models for the Local Group and the acquisition of its angular momentum. We describe early attempts to understand the origin of the spin of the galaxies discussing the hypothesis that the Local Group has little angular momentum. Finally we show that using Peebles` least action principle there should be a rather large amount of orbital angular momentum compared to the magnitude of the spin of its galaxies. Therefore the Local Group cannot be thought as tidally isolated. Using Peebles` trajectories we give a possible set of trajectories for Local Group galaxies which would predict their spin.

  3. Deconstructing spatiotemporal chaos using local symbolic dynamics.

    PubMed

    Pethel, Shawn D; Corron, Ned J; Bollt, Erik

    2007-11-23

    We find that the global symbolic dynamics of a diffusively coupled map lattice is well approximated by a very small local model for weak to moderate coupling strengths. A local symbolic model is a truncation of the full symbolic model to one that considers only a single element and a few neighbors. Using interval analysis, we give rigorous results for a range of coupling strengths and different local model widths. Examples are presented of extracting a local symbolic model from data and of controlling spatiotemporal chaos. PMID:18233220

  4. Origin of Dynamical Quantum Non-locality

    NASA Astrophysics Data System (ADS)

    Pachon, Cesar E.; Pachon, Leonardo A.

    2014-03-01

    Non-locality is one of the hallmarks of quantum mechanics and is responsible for paradigmatic features such as entanglement and the Aharonov-Bohm effect. Non-locality comes in two ``flavours'': a kinematic non-locality- arising from the structure of the Hilbert space- and a dynamical non-locality- arising from the quantum equations of motion-. Kinematic non-locality is unable to induce any change in the probability distributions, so that the ``action-at-a-distance'' cannot manifest. Conversely, dynamical non-locality does create explicit changes in probability, though in a ``causality-preserving'' manner. The origin of non-locality of quantum measurements and its relations to the fundamental postulates of quantum mechanics, such as the uncertainty principle, have been only recently elucidated. Here we trace the origin of dynamical non-locality to the superposition principle. This relation allows us to establish and identify how the uncertainty and the superposition principles determine the non-local character of the outcome of a quantum measurement. Being based on group theoretical and path integral formulations, our formulation admits immediate generalizations and extensions to to, e.g., quantum field theory. This work was supported by the Departamento Administrativo de Ciencia, Tecnologia e Innovacion -COLCIENCIAS- of Colombia under the grant number 111556934912.

  5. Functional Localization of Genetic Network Programming

    NASA Astrophysics Data System (ADS)

    Eto, Shinji; Hirasawa, Kotaro; Hu, Jinglu

    According to the knowledge of brain science, it is suggested that there exists cerebral functional localization, which means that a specific part of the cerebrum is activated depending on various kinds of information human receives. The aim of this paper is to build an artificial model to realize functional localization based on Genetic Network Programming (GNP), a new evolutionary computation method recently developed. GNP has a directed graph structure suitable for realizing functional localization. We studied the basic characteristics of the proposed system by making GNP work in a functionally localized way.

  6. Lipid Emulsion for Local Anesthetic Systemic Toxicity

    PubMed Central

    Ciechanowicz, Sarah; Patil, Vinod

    2012-01-01

    The accidental overdose of local anesthetics may prove fatal. The commonly used amide local anesthetics have varying adverse effects on the myocardium, and beyond a certain dose all are capable of causing death. Local anesthetics are the most frequently used drugs amongst anesthetists and although uncommon, local anaesthetic systemic toxicity accounts for a high proportion of mortality, with local anaesthetic-induced cardiac arrest particularly resistant to standard resuscitation methods. Over the last decade, there has been convincing evidence of intravenous lipid emulsions as a rescue in local anesthetic-cardiotoxicity, and anesthetic organisations, over the globe have developed guidelines on the use of this drug. Despite this, awareness amongst practitioners appears to be lacking. All who use local anesthetics in their practice should have an appreciation of patients at high risk of toxicity, early symptoms and signs of toxicity, preventative measures when using local anesthetics, and the initial management of systemic toxicity with intravenous lipid emulsion. In this paper we intend to discuss the pharmacology and pathophysiology of local anesthetics and toxicity, and the rationale for lipid emulsion therapy. PMID:21969824

  7. Updates of Topical and Local Anesthesia Agents.

    PubMed

    Boyce, Ricardo A; Kirpalani, Tarun; Mohan, Naveen

    2016-04-01

    As described in this article, there are many advances in topical and local anesthesia. Topical and local anesthetics have played a great role in dentistry in alleviating the fears of patients, eliminating pain, and providing pain control. Many invasive procedures would not be performed without the use and advances of topical/local anesthetics. The modern-day dentist has the responsibility of knowing the variety of products on the market and should have at least references to access before, during, and after treatment. This practice ensures proper care with topical and local anesthetics for the masses of patients entering dental offices worldwide. PMID:27040295

  8. Local and normal modes: A classical perspective

    NASA Astrophysics Data System (ADS)

    Jaffé, Charles; Brumer, Paul

    1980-12-01

    Normal and local mode behavior in molecular systems and the transition between them is explored using nonlinear mechanics techniques. Significant insight into this behavior and into the structure of phase space results from a generalized definition of local and normal modes and the associated identification of normal modes as a (1:1) resonance between local zeroth order oscillators. In addition to qualitative insight, this approach yields a simple formula [Eq. (28)] for the level of excitation at which local modes become possible. Applications to H2O and to the overtone spectroscopy of the dihalomethanes, benzene, and TMS are provided.

  9. When local isn't best

    PubMed Central

    Jones, Thomas A

    2013-01-01

    This paper attempts to explain circumstances under which local may be or may not be best. Natural selection may lead to local adaptation (LA), or it may be constrained by gene flow, founder effects, small population size, genetic drift, and archetype. ‘Specialist’ species display greater LA than ‘generalist’ species. Local genotypes are to a certain extent transient, being a consequence of past historical genetic patterns. Two recent meta-analyses found that while local performance exceeded the performance of a randomly chosen nonlocal population in 71% of comparisons, general adaptation across environments was as frequent as LA. Genotypes for restoration are most likely to be effective if they are adapted to current site conditions. As environmental change accelerates, both globally and locally, exceptions to ‘local is best’ may increase. For these reasons, ‘local is best’ may be better thought of as a testable hypothesis rather than as a general assumption. While either local or nonlocal plant material may be most effective for restoration practice depending on individual circumstances, local material will continue to be the first choice for restoration practitioners whenever this option is feasible and effective. PMID:24187591

  10. Detection of edges using local geometry

    NASA Technical Reports Server (NTRS)

    Gualtieri, J. A.; Manohar, M.

    1989-01-01

    Researchers described a new representation, the local geometry, for early visual processing which is motivated by results from biological vision. This representation is richer than is often used in image processing. It extracts more of the local structure available at each pixel in the image by using receptive fields that can be continuously rotated and that go to third order spatial variation. Early visual processing algorithms such as edge detectors and ridge detectors can be written in terms of various local geometries and are computationally tractable. For example, Canny's edge detector has been implemented in terms of a local geometry of order two, and a ridge detector in terms of a local geometry of order three. The edge detector in local geometry was applied to synthetic and real images and it was shown using simple interpolation schemes that sufficient information is available to locate edges with sub-pixel accuracy (to a resolution increase of at least a factor of five). This is reasonable even for noisy images because the local geometry fits a smooth surface - the Taylor series - to the discrete image data. Only local processing was used in the implementation so it can readily be implemented on parallel mesh machines such as the MPP. Researchers expect that other early visual algorithms, such as region growing, inflection point detection, and segmentation can also be implemented in terms of the local geometry and will provide sufficiently rich and robust representations for subsequent visual processing.

  11. Target localization and real-time tracking using the Calypso 4D localization system in patients with localized prostate cancer

    SciTech Connect

    Willoughby, Twyla R.; Kupelian, Patrick A. . E-mail: patrick.kupelian@orhs.org; Pouliot, Jean; Shinohara, Katsuto; Aubin, Michelle; Roach, Mack; Skrumeda, Lisa L.; Balter, James M.; Litzenberg, Dale W.; Hadley, Scott W.; Wei, John T.; Sandler, Howard M.

    2006-06-01

    Purpose: The Calypso 4D Localization System is being developed to provide accurate, precise, objective, and continuous target localization during radiotherapy. This study involves the first human use of the system, to evaluate the localization accuracy of this technique compared with radiographic localization and to assess its ability to obtain real-time prostate-motion information. Methods and Materials: Three transponders were implanted in each of 20 patients. Eleven eligible patients of the 20 patients participated in a study arm that compared radiographic triangulated transponder locations to electromagnetically recorded transponder locations. Transponders were tracked for 8-min periods. Results: The implantations were all successful, with no major complications. Intertransponder distances were largely stable. Comparison of the patient localization on the basis of transponder locations as per the Calypso system with the radiographic transponder localization showed an average ({+-}SD) 3D difference of 1.5 {+-} 0.9 mm. Upon tracking during 8 min, 2 of the 11 patients showed significant organ motion (>1 cm), with some motion lasting longer that 1 min. Conclusion: Calypso transponders can be used as magnetic intraprostatic fiducials. Clinical evaluation of this novel 4D nonionizing electromagnetic localization system with transponders indicates a comparable localization accuracy to isocenter (within 2 mm) compared with X-ray localiza0010ti.

  12. Estudio teórico del CO2. Orbitales de valencia y del ``core''

    NASA Astrophysics Data System (ADS)

    Olalla Gutiérrez, E.

    Hemos calculado las intensidades de las transiciones E1 a los miembros de las series de Rydberg con origen en los orbitales ``no enlazantes'' del dióxido de carbono, especie de conocida relevancia atmosférica. Se han computado, asimismo, los continuos de fotoionización correspondientes a los distintos canales de ionización, representándolos como densidad espectral de fuerza de oscilador frente a la energía del fotón incidente; mostramos los resultados df/dE para la fotoionización total de esta especie en el intervalo 15-60 eV. Todos los cálculos se han llevado a cabo mediante la formulación Molecular del Método de los Orbitales de Defecto Cuántico, MQDO [1,2]. La calidad de los resultados que presentamos se ha evaluado en base a la comparación con los datos, tanto experimentales como teóricos, disponibles en la bibliografía. El acuerdo encontrado es altamente satisfactorio

  13. Neurological aspects of del(1q) syndrome.

    PubMed

    Murayama, K; Greenwood, R S; Rao, K W; Aylsworth, A S

    1991-09-15

    We have studied three children with de novo terminal deletion of the long arm of chromosome 1 (46,XX,del(1)(q43)). They all have minor anomalies and neurological signs (severe psychomotor developmental delay, generalized hypotonia, and seizures) that have been described previously. In addition, all of these three patients have autistic-like behavior. They avoid eye contact, show no interest in people, express little emotion, and repeat stereotypic movements such as head nodding and purposeless finger manipulation. They also spend excessive time in making unusual sounds consisting of a high-pitched shrill cry with little intonation in infancy and a harsh, strained, and glottal stridency in later life. They make no labial, lingual, or nasal sounds. We suggest that these observations may be unique clinical manifestations of certain terminal 1q deletions. PMID:1746617

  14. Illuminating water and life: Emilio Del Giudice.

    PubMed

    Ho, Mae-Wan

    2015-01-01

    The quantum electrodynamics theory of water put forward by Del Giudice and colleagues provides a useful foundation for a new science of water for life. The interaction of light with liquid water generates quantum coherent domains in which the water molecules oscillate between the ground state and an excited state close to the ionizing potential of water. This produces a plasma of almost free electrons favoring redox reactions, the basis of energy metabolism in living organisms. Coherent domains stabilized by surfaces, such as membranes and macromolecules, provide the excited interfacial water that enables photosynthesis to take place, on which most of life on Earth depends. Excited water is the source of superconducting protons for rapid intercommunication within the body. Coherent domains can also trap electromagnetic frequencies from the environment to orchestrate and activate specific biochemical reactions through resonance, a mechanism for the most precise regulation of gene function. PMID:26098522

  15. Localization Algorithms of Underwater Wireless Sensor Networks: A Survey

    PubMed Central

    Han, Guangjie; Jiang, Jinfang; Shu, Lei; Xu, Yongjun; Wang, Feng

    2012-01-01

    In Underwater Wireless Sensor Networks (UWSNs), localization is one of most important technologies since it plays a critical role in many applications. Motivated by widespread adoption of localization, in this paper, we present a comprehensive survey of localization algorithms. First, we classify localization algorithms into three categories based on sensor nodes’ mobility: stationary localization algorithms, mobile localization algorithms and hybrid localization algorithms. Moreover, we compare the localization algorithms in detail and analyze future research directions of localization algorithms in UWSNs. PMID:22438752

  16. The Last Glacial Maximum and Termination in the Torres del Paine Region, Southern South America

    NASA Astrophysics Data System (ADS)

    Garcia, J.; Hall, B. L.; Kaplan, M. R.; Vega, R. M.; Binnie, S.; Gómez, G.; Santana, F.

    2012-12-01

    Deciphering the timing, structure and termination of the local last glacial maximum (LGM) throughout Patagonia (42-55 S) remains one of the key unsolved paleoclimate questions in Quaternary sciences. During the last glaciation, the Patagonian ice sheet formed one ice body along the Patagonian Andes (42-55 S) in southern South America, but previous work has revealed different spatiotemporal ice dynamics along the eastern and western ice margins. The Patagonian Andes is the only landmass that exists at this latitude confronting the southern westerly wind belt, which seems to have played a key role in past glacial and climate changes. Therefore, reconstructing southern Andes glacier history constitutes a key element for understanding the causes of glaciations in the Southern Hemisphere. Major progress has been made to document the local Late-Pleistocene glacier history, particularly in response to recent application of exposure-cosmogenic dating technique in the region, although only sparse well-dated paleoclimate records exist in this vast area. LGM moraine-based records in south Patagonia (~48-55 S) have been developed for the Strait of Magellan area, where full glacial conditions seems to have occurred between ~28.0 - 17.5 ka. Despite that these data seem to confirm previous glacial chronologies developed in north Patagonia and the Chilean Lake District (40-42 S), recent works in Torres del Paine and Última Esperanza basins (50-51 S), suggest that glacial maximum conditions may have occurred earlier (i.e., during Marine Isotope Stage 3) and that ice extent could have been twice the size of previously thought. Here, we discuss paleoclimatological implications from our 10Be and 26Al-dating program of moraines in the Torres del Paine region in southern Patagonia. We focused our efforts in the previously undated Río de las Viscachas (RV) I and II moraines, which occur distal to the late-glacial TDP II, III and IV moraines that enclose present lake bodies at the

  17. Local cooling despite global warming

    NASA Astrophysics Data System (ADS)

    Girihagama, Lakshika Nilmini Kumari

    How much warmer is the ocean surface than the atmosphere directly above it? Part 1 of the present study offers a means to quantify this temperature difference using a nonlinear one-dimensional global energy balance coupled ocean--atmosphere model ("Aqua Planet"). The significance of our model, which is of intermediate complexity, is its ability to obtain an analytical solution for the global average temperatures. Preliminary results show that, for the present climate, global mean ocean temperature is 291.1 K whereas surface atmospheric temperature is 287.4 K. Thus, the surface ocean is 3.7 K warmer than the atmosphere above it. Temporal perturbation of the global mean solution obtained for "Aqua Planet" showed a stable system. Oscillation amplitude of the atmospheric temperature anomaly is greater in magnitude to those found in the ocean. There is a phase shift (a lag in the ocean), which is caused by oceanic thermal inertia. Climate feedbacks due to selected climate parameters such as incoming radiation, cloud cover, and CO2 are discussed. Warming obtained with our model compares with Intergovernmental Panel on Climate Change's (IPCC) estimations. Application of our model to local regions illuminates the importance of evaporative cooling in determining derived air-sea temperature offsets, where an increase in the latter increases the systems overall sensitivity to evaporative cooling. In part 2, we wish to answer the fairly complicated question of whether global warming and an increased freshwater flux cause Northern Hemispheric warming or cooling. Starting from the assumption of the ocean as the primary source of variability in the Northern hemispheric ocean--atmosphere coupled system, we employed a simple non--linear one--dimensional coupled ocean--atmosphere model similar to the "Aqua Planet" model but with additional advective heat transports. The simplicity of this model allows us to analytically predict the evolution of many dynamical variables of interest

  18. Wave maps from Gödel's universe

    NASA Astrophysics Data System (ADS)

    Barletta, Elisabetta; Dragomir, Sorin; Magliaro, Marco

    2014-10-01

    Using a result by Koch (1988 Trans. Am. Math. Soc. 307 827-41) we realize Gödel's universe G_{α }^{4}=({{{R}}^{4}},{{g}_{α}}) as the total space of a principal {R}-bundle over a strictly pseudo-convex CR manifold M3 and exploit the analogy between {{g}_{Yalpha;}} and Fefferman's metric {{F}_{θ}} (Fefferman 1976 Ann. Math. 103 395-416 104 393-4) to show that for any {R}-invariant wave map Φ of G_{α}^{4} into a Riemannian manifold N, the corresponding base map φ :{{M}^{3}}\\to N is subelliptic harmonic, with respect to a canonical choice of contact form θ on M3. We show that the subelliptic Jacobi operator J_{b}^{φ} of ϕ has a discrete Dirichlet spectrum on any bounded domain D\\subset {{M}^{3}} supporting the Poincaré inequality on \\mathop{W}\\limits^{\\circ }{}_{H}^{1,2}(D,{{φ}^{-1}}TN) and Kondrakov compactness, i.e. compactness of the embedding \\mathop{W}\\limits^{\\circ }{}_{H}^{1,2}(D,{{φ }^{-1}}TN)\\hookrightarrow {{L}^{2}}(D,{{φ}^{-1}}TN). We exhibit an explicit solution π :G_{α}^{4}\\to {{M}^{3}} to the wave map system on G_{α}^{4}, of index in{{d}^{Ω}}(π)\\geqslant 1 for any bounded domain Ω \\subset G_{α}^{4}. Mounoud's distance (Mounoud 2001 Differ. Geom. Appl. 15 47-57) d_{{{G}_{0}}, Ω }^{∞}({{g}_{α }}, {{F}_{θ}}) is bounded below by a constant depending only on the rotation frequency of Gödel's universe, thus giving a measure of the bias of {{g}_{α}} from being Fefferman like in the region Ω \\subset {{{R}}^{4}}.

  19. The Del Mod System: An External Evaluation, Final Report, Volume IV.

    ERIC Educational Resources Information Center

    Humphreys, Donald W.; And Others

    This is one of five volumes prepared to describe various aspects of the Del Mod System. This volume deals with the evaluation of the Del Mod System. Included are the following: (1) Del Mod Responsive Evaluation; (2) Evaluation Outcomes; (3) Validation of the Del Mod Responsive Evaluation Process; and (4) Conclusions. Appendices include: (A)…

  20. A Descriptive Analysis of the Del Mod System's Field Agent Component, Final Report, Volume III.

    ERIC Educational Resources Information Center

    Golts, Uldis R.

    This monograph describes the field agent of the Delaware Del Mod System. The following sections are included in the report: (1) The Duties and Activities of the Del Mod System Field Agents; (2) The Field Agents' Mode of Operation; (3) The Conduct of Projects; (4) The Hiring and Training of Del Mod Field Agents; (5) The Administration of Del Mod…

  1. Challenges of modeling current very large lahars at Nevado del Huila Volcano, Colombia

    NASA Astrophysics Data System (ADS)

    Worni, Raphael; Huggel, Christian; Stoffel, M.; Pulgarín, B.

    2012-03-01

    Nevado del Huila, a glacier-covered volcano in the South of Colombia's Cordillera Central, had not experienced any historical eruptions before 2007. In 2007 and 2008, the volcano erupted with phreatic and phreatomagmatic events which produced lahars with flow volumes of up to about 300 million m3 causing severe damage to infrastructure and loss of lives. The magnitude of these lahars and the prevailing potential for similar or even larger events, poses significant hazards to local people and makes appropriate modeling a real challenge. In this study, we analyze the recent lahars to better understand the main processes and then model possible scenarios for future events. We used lahar inundation depths, travel duration, and flow deposits to constrain the dimensions of the 2007 event and applied LAHARZ and FLO-2D for lahar modeling. Measured hydrographs, geophone seismic sensor data and calculated peak discharges served as input data for the reconstruction of flow hydrographs and for calibration of the models. For model validation, results were compared with field data collected along the Páez and Simbola Rivers. Based on the results of the 2007 lahar simulation, we modeled lahar scenarios with volumes between 300 million and 1 billion m3. The approach presented here represents a feasible solution for modeling high-magnitude flows like lahars and allows an assessment of potential future events and related consequences for population centers downstream of Nevado del Huila.

  2. Light scattering from aerosol particles in the El Paso del Norte region / the effect of humidity

    NASA Astrophysics Data System (ADS)

    Medina Calderon, Richard

    Atmospheric aerosols play an important role in climate forcing, through scattering and absorption of the incoming solar radiation. The extinction of light by the presence of atmospheric aerosols was studied using two first-principle models, and corresponding computer codes. In the first model the extinction of light from irregularly shaped aerosol particles was analyzed. In the second model it was assumed that the irregularly shaped aerosol particles were covered by a film of water, and the hygroscopicity and the extinction of light by the aerosols was analyzed. These models were then applied to the Paso del Norte region and their light extinction results compared with a local extinctiometer. The inter-comparison of the models extinction results and the extinctiometer values were well correlated. It was observed that for high humidity days the model that used an aerosol particle covered with a water film correlated better with the experimental extinctiometer measurements. While these two models were validated in the Paso del Norte region, they are also applicable to any other region, under humid or dry atmospheric conditions.

  3. Hormonal and Local Regulation of Bone Formation.

    ERIC Educational Resources Information Center

    Canalis, Ernesto

    1985-01-01

    Reviews effects of hormones, systemic factors, and local regulators on bone formation. Identifies and explains the impact on bone growth of several hormones as well as the components of systemic and local systems. Concentrates on bone collagen and DNA synthesis. (Physicians may earn continuing education credit by completing an appended test). (ML)

  4. Localized surface instabilities of stressed solids

    SciTech Connect

    Colin, J.; Grilhe, J.; Junqua, N.

    1998-12-31

    Localized instabilities formation on the free surface of solids has been studied when sources of non-homogeneous stress such as dislocations or precipitates are present in the bulk. This formalism of localized perturbations has been used to describe the butterfly transformation of cubic precipitates in superalloys and the contraction of rectangular specimens under stress.

  5. Content Locality in Distributed Digital Libraries.

    ERIC Educational Resources Information Center

    Viles, Charles L.; French, James C.

    1999-01-01

    Introduces content locality--the degree to which content-similar documents are colocated in a distributed collection--in distributed digital libraries. Proposes two metrics for measurement of content locality, one based on topic signatures and the other based on collection statistics. Provides derivations and analysis of both metrics and uses them…

  6. Federal Grants to State and Local Governments

    ERIC Educational Resources Information Center

    Congressional Budget Office, 2013

    2013-01-01

    In fiscal year 2011, the federal government provided $607 billion in grants to state and local governments. Those funds accounted for 17 percent of federal outlays, 4 percent of gross domestic product (GDP), and a quarter of spending by state and local governments that year. Over the past 30 years, those "intergovernmental" grants--financial…

  7. How State and Local Interagency Partnerships Work.

    ERIC Educational Resources Information Center

    Rachal, Patricia, Ed.

    1996-01-01

    This newsletter theme issue describes a state-local team partnership model for interagency transition efforts for young adults with deaf-blindness. Excepts from a presentation by Jane M. Everson identify key aspects and characteristics of effective state and local interagency partnerships. These include: (1) strategies for initiating and…

  8. Local Administrators Planning Handbook. Final Report.

    ERIC Educational Resources Information Center

    Dyrenfurth, Michael J.; Dunlap, William S.

    As part of a project to develop a planning guide to assist local vocational education administrators in improving their planning efforts, a needs assessment questionnaire was developed to identify the degree of need for assistance in planning activities. Two hundred sixty-four Missouri local vocational administrators completed the pilot-tested…

  9. Engaging Senior Citizens in Local Education

    ERIC Educational Resources Information Center

    Geier, Brett A.

    2012-01-01

    During the past several years, school district personnel have faced an arduous task of convincing a local electorate--including those who are not directly associated with local schools--to increase its own tax rate. Convincing demographic groups that have a vital interest in improving school facilities can be an easier task. Parents who want to…

  10. Local and Global Thinking in Statistical Inference

    ERIC Educational Resources Information Center

    Pratt, Dave; Johnston-Wilder, Peter; Ainley, Janet; Mason, John

    2008-01-01

    In this reflective paper, we explore students' local and global thinking about informal statistical inference through our observations of 10- to 11-year-olds, challenged to infer the unknown configuration of a virtual die, but able to use the die to generate as much data as they felt necessary. We report how they tended to focus on local changes…

  11. How to be a local media celebrity.

    PubMed

    Trent, Nancy

    2009-01-01

    Building relationships with the media in your region can turn you into a local "media darling. "As a PR-savvy doctor, there are certain techniques to get you the media attention you desire. This article will offer tips for getting local media on your side and working with media, and ways to mobilize your vendors to garner PR in your region. PMID:19455864

  12. 22 CFR 228.40 - Local procurement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Local procurement. 228.40 Section 228.40 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES ON SOURCE, ORIGIN AND NATIONALITY FOR COMMODITIES AND SERVICES FINANCED BY USAID Conditions Governing Source and Nationality of Local...

  13. 44 CFR 60.26 - Local coordination.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Flood-Related Erosion-Prone Areas § 60.26 Local coordination. (a) Local flood plain, mudslide (i.e., mudflow) and flood-related erosion area management, forecasting, emergency preparedness, and damage...., mudflow) and flood-related erosion regulations; (c) A community should notify adjacent communities...

  14. 44 CFR 60.26 - Local coordination.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Flood-Related Erosion-Prone Areas § 60.26 Local coordination. (a) Local flood plain, mudslide (i.e., mudflow) and flood-related erosion area management, forecasting, emergency preparedness, and damage...., mudflow) and flood-related erosion regulations; (c) A community should notify adjacent communities...

  15. 44 CFR 60.26 - Local coordination.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Flood-Related Erosion-Prone Areas § 60.26 Local coordination. (a) Local flood plain, mudslide (i.e., mudflow) and flood-related erosion area management, forecasting, emergency preparedness, and damage...., mudflow) and flood-related erosion regulations; (c) A community should notify adjacent communities...

  16. 44 CFR 60.26 - Local coordination.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Flood-Related Erosion-Prone Areas § 60.26 Local coordination. (a) Local flood plain, mudslide (i.e., mudflow) and flood-related erosion area management, forecasting, emergency preparedness, and damage...., mudflow) and flood-related erosion regulations; (c) A community should notify adjacent communities...

  17. 44 CFR 60.26 - Local coordination.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Flood-Related Erosion-Prone Areas § 60.26 Local coordination. (a) Local flood plain, mudslide (i.e., mudflow) and flood-related erosion area management, forecasting, emergency preparedness, and damage...., mudflow) and flood-related erosion regulations; (c) A community should notify adjacent communities...

  18. REL3.0 SW DAILY LOCAL

    Atmospheric Science Data Center

    2016-06-02

    ... Budget (SRB) Release 3.0 GEWEX Shortwave Daily Local Time Data in Native grid binary format   News:  GEWEX ... Temporal Resolution:  Daily from 3-hourly Local Sun time values File Format:  BINARY Tools:  ...

  19. When local isn't best

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Local plant materials are often preferred for the practice of ecological restoration, and this is likely related to the preference for pristine lands for study by the scientific community. While the 'local-is-best' plant material paradigm may be appropriate for pristine lands, it may not be directl...

  20. Local Implementation and Land Use Decision Making.

    ERIC Educational Resources Information Center

    Garlasco, Chris; And Others

    This material includes student guide sheets, reference material, and tape script for the audio-tutorial unit on Local Implementation. An audio tape is used with the materials. The material is designed for use with Connecticut schools, but can be adapted to other localities. The material in this unit emphasizes the role of planning and zoning in…

  1. Sharing Local Revenue: One District's Perspective

    ERIC Educational Resources Information Center

    Cline, David S.

    2011-01-01

    The vast majority of U.S. school districts are considered independent and have taxing authority; the remaining districts rely on revenue and budgetary approval from their local government. In the latter case, localities often use some form of negotiated process to determine the amount of revenue their school districts will receive. Typically, a…

  2. Engaging Students through Mapping Local History

    ERIC Educational Resources Information Center

    Mitchell, Katharyne; Elwood, Sarah

    2012-01-01

    This article argues that the integration of local history and geography through collaborative digital mapping can lead to greater interest in civic participation by early adolescent learners. In the study, twenty-nine middle school students were asked to research, represent, and discuss local urban sites of historical significance on an…

  3. State and Local Revenue Potential 1975.

    ERIC Educational Resources Information Center

    Quindry, Kenneth E.

    This publication presents numerous statistical tables that summarize 1975 data on state and local tax effort for the 50 states and the District of Columbia, with an eye toward identifying possible underutilization of specific taxes. The report consists of three separate parts. First, state and local tax collections are compiled by source and by…

  4. Secondary School Education and Local Governments.

    ERIC Educational Resources Information Center

    Leland, Robert C.

    1974-01-01

    The aim of this publication is to aid city management's participation in improving education on local government. The need for such participation is evident from the lack of progress in the teaching of local government since a 1963 report on the topic. Difficulties, such as insufficient class time, inadequate resources, teachers unfamiliar with…

  5. State and Local Revenue Potential, 1971.

    ERIC Educational Resources Information Center

    Quindry, Kenneth E.

    This report provides an analysis of State-local tax structures in 50 States and the District of Columbia and is primarily an updating of tables in previous reports. The major purpose of the study is to indicate to State and local officials those tax areas in which their revenue effort is either below or above the average effort of the 50 States…

  6. Chemical Aspects of Local and Regional Anesthesia

    ERIC Educational Resources Information Center

    Brunsvold, Robert; Ostercamp, Daryl L.

    2006-01-01

    The practical sides of local or regional anesthesia are explained by two applications of local anesthetics under moderately demanding circumstances. The examples illustrated are surgical repair of the severed lower tendon of the left index finger and the case of pregnant woman involving the delivery of a child in the early stages of cervical…

  7. State and Local Revenue Potential, 1970.

    ERIC Educational Resources Information Center

    Quindry, Kenneth E.

    This report contains results of an extensive study into State and local tax revenue potentials for the 15 Southern Regional Education Board (SREB) States and presents quantitative data on the 50 State-local tax systems. Data set forth in the 35 statistical tables enable the researcher to compare his State's total tax revenues with those of each of…

  8. Local History and Problem-Based Learning

    ERIC Educational Resources Information Center

    Wieseman, Katherine C.; Cadwell, Doni

    2005-01-01

    The combination of students, local history, researching, and problem-based learning creates a powerful opportunity for learning to all involved. This article provides one example of how an elementary teacher and a teacher educator have used local resources and problem-based learning to teach a fourth grade unit about human communities and the…

  9. Natural geometric representation for electron local observables

    SciTech Connect

    Minogin, V.G.

    2014-03-15

    An existence of the quartic identities for the electron local observables that define orthogonality relations for the 3D quantities quadratic in the electron observables is found. It is shown that the joint solution of the quartic and bilinear identities for the electron observables defines a unique natural representation of the observables. In the natural representation the vector type electron local observables have well-defined fixed positions with respect to a local 3D orthogonal reference frame. It is shown that the natural representation of the electron local observables can be defined in six different forms depending on a choice of the orthogonal unit vectors. The natural representation is used to determine the functional dependence of the electron wave functions on the local observables valid for any shape of the electron wave packet. -- Highlights: •Quartic identities that define the orthogonality relations for the electron local observables are found. •Joint solution of quartic and bilinear identities defines a unique natural representation of the electron local observables. •Functional dependence of the electron wave functions on the electron local observables is determined.

  10. Locally accessible information and distillation of entanglement

    SciTech Connect

    Ghosh, Sibasish; Joag, Pramod; Kar, Guruprasad; Kunkri, Samir; Roy, Anirban

    2005-01-01

    A different type of complementarity relation is found between locally accessible information and final average entanglement for a given ensemble. It is also shown that in some well-known distillation protocols, this complementary relation is optimally satisfied. We discuss the interesting trade-off between locally accessible information and distillable entanglement for some states.

  11. Researching, Writing, and Publishing Local History.

    ERIC Educational Resources Information Center

    Felt, Thomas E.

    The book provides practical guidelines for the layman who is interested in researching, writing, and publishing local history. Two standards considered to be essential to the writing of local history are ethics and competence. The three aspects of competence which are discussed focus on researching, writing, and publishing. Chapter I identifies…

  12. History of Schooling: Politics and Local Practice

    ERIC Educational Resources Information Center

    Aubry, Carla, Ed.; Westberg, Johannes, Ed.

    2012-01-01

    The relationship between education policy and local practices is at the core of research pertaining to the history of education. In this volume, the authors examine this issue from a multitude of perspectives, presenting a broad and comprehensive picture of schooling on international, national and local levels. Three issues of great significance,…

  13. Localizing Region-Based Active Contours

    PubMed Central

    Lankton, Shawn; Tannenbaum, Allen

    2009-01-01

    In this paper, we propose a natural framework that allows any region-based segmentation energy to be re-formulated in a local way. We consider local rather than global image statistics and evolve a contour based on local information. Localized contours are capable of segmenting objects with heterogeneous feature profiles that would be difficult to capture correctly using a standard global method. The presented technique is versatile enough to be used with any global region-based active contour energy and instill in it the benefits of localization. We describe this framework and demonstrate the localization of three well-known energies in order to illustrate how our framework can be applied to any energy. We then compare each localized energy to its global counterpart to show the improvements that can be achieved. Next, an in-depth study of the behaviors of these energies in response to the degree of localization is given. Finally, we show results on challenging images to illustrate the robust and accurate segmentations that are possible with this new class of active contour models. PMID:18854247

  14. Developing Partnerships to Promote Local Innovation

    ERIC Educational Resources Information Center

    Waters-Bayer, Ann; van Veldhuizen, Laurens; Wettasinha, Chesha; Wongtschowski, Mariana

    2004-01-01

    Local innovation in agriculture and natural resource management is the process through which individuals or groups discover or develop new and better ways of managing resources, building on and expanding the boundaries of their existing knowledge. Prolinnova (Promoting Local Innovation) is a NGO-led global partnership programme that is being built…

  15. 34 CFR 200.30 - Local review.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Programs Operated by Local Educational Agencies Lea and School Improvement § 200.30 Local review. (a) Each... described in § 200.2 to review annually the progress of each school served under subpart A of this part to determine whether the school is making AYP in accordance with § 200.20. (b)(1) In reviewing the progress...

  16. Local Control: Use It or Lose It.

    ERIC Educational Resources Information Center

    California School Boards Association, Sacramento.

    Two California laws have increased the autonomy of local school districts. As of January 1982, virtually all provisions of the California Education Code can be waived at the request of local school boards with the approval of the state board of education. Under Article 2 of Assembly Bill 777, Chapter 100, programs that may be waived include state…

  17. Promoting Creativity in Local Tourist Businesses

    ERIC Educational Resources Information Center

    Perivoliotis-Chryssovergis, Margaret-Catherine

    2007-01-01

    This paper discusses an e-learning pilot study focusing on local tourist producers and businesses involved in the production of artefacts, mainly textiles. The project included research into the possibilities of incorporating the strengths of local cultural heritage as a vital starting point for design creativity, innovation, production and…

  18. LOCAL DECOUPLING IN THE LHC INTERACTION REGIONS

    SciTech Connect

    PILAT,F.

    1999-09-07

    Local decoupling is a technique to correct coupling locally and operationally, that is, without a priori knowledge of the underlying skew quadrupole errors. The method is explained and applied to the correction of coupling in the interaction regions of the LHC at collision.

  19. Local form interference in biological motion perception.

    PubMed

    Kerr-Gaffney, Jess E; Hunt, Amelia R; Pilz, Karin S

    2016-07-01

    Replacing the local dots of point-light walkers with complex images leads to significant detriments to performance in biological motion detection and discrimination tasks. This detriment has previously been shown to be larger when the local elements match the global shape in object category and facing direction. In contrast, studies using Navon stimuli have demonstrated that local interference on global processing primarily occurs when local elements are dissimilar to the global form. In 3 experiments, we investigated this contradiction by replacing the local dots of a point-light walker with human images or stick figures. Participants were significantly faster and more accurate at discriminating the facing and walking direction of a walker when the local images were facing in the same direction as the global walker than when they were facing in the opposite direction. These results provide support for the idea that organization of biological motion depends on allocation of limited processing resources to the global motion information when the local elements are complex. However, there is more disruption to global form processing when the local elements and global form conflict in task-related properties. PMID:27016343

  20. Universal mechanism for Anderson and weak localization.

    PubMed

    Filoche, Marcel; Mayboroda, Svitlana

    2012-09-11

    Localization of stationary waves occurs in a large variety of vibrating systems, whether mechanical, acoustical, optical, or quantum. It is induced by the presence of an inhomogeneous medium, a complex geometry, or a quenched disorder. One of its most striking and famous manifestations is Anderson localization, responsible for instance for the metal-insulator transition in disordered alloys. Yet, despite an enormous body of related literature, a clear and unified picture of localization is still to be found, as well as the exact relationship between its many manifestations. In this paper, we demonstrate that both Anderson and weak localizations originate from the same universal mechanism, acting on any type of vibration, in any dimension, and for any domain shape. This mechanism partitions the system into weakly coupled subregions. The boundaries of these subregions correspond to the valleys of a hidden landscape that emerges from the interplay between the wave operator and the system geometry. The height of the landscape along its valleys determines the strength of the coupling between the subregions. The landscape and its impact on localization can be determined rigorously by solving one special boundary problem. This theory allows one to predict the localization properties, the confining regions, and to estimate the energy of the vibrational eigenmodes through the properties of one geometrical object. In particular, Anderson localization can be understood as a special case of weak localization in a very rough landscape. PMID:22927384

  1. 47 CFR 69.106 - Local switching.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Local switching. 69.106 Section 69.106... Computation of Charges § 69.106 Local switching. (a) Except as provided in § 69.118, charges that are... switching facilities for the provision of interstate or foreign services. (b) The per minute...

  2. Anderson localization in metallic nanoparticle arrays

    NASA Astrophysics Data System (ADS)

    Mai, Zhijie; Lin, Fang; Pang, Wei; Xu, Haitao; Tan, Suiyan; Fu, Shenhe; Li, Yongyao

    2016-06-01

    Anderson localization has been observed in various types of waves, such as matter waves, optical waves and acoustic waves. Here we reveal that the effect of Anderson localization can be also induced in metallic nonlinear nanoparticle arrays excited by a random electrically driving field. We find that the dipole-induced nonlinearity results in ballistic expansion of dipole intensity during evolution; while the randomness of the external driving field can suppress such an expansion. Increasing the strength of randomness above the threshold value, a localized pattern of dipole intensity can be generated in the metallic nanoparticle arrays. By means of statistics, the mean intensity distribution of the dipoles reveals the formation of Anderson localization. We further show that the generated Anderson localization is highly confined, with its size down to the scale of incident wavelength. The reported results might facilitate the manipulations of electromagnetic fields in the scale of wavelength.

  3. Protein localization with flexible DNA or RNA.

    PubMed

    Bernhardsson, Sebastian; Mitarai, Namiko; Sneppen, Kim

    2012-01-01

    Localization of activity is ubiquitous in life, and also within sub-cellular compartments. Localization provides potential advantages as different proteins involved in the same cellular process may supplement each other on a fast timescale. It might also prevent proteins from being active in other regions of the cell. However localization is at odds with the spreading of unbound molecules by diffusion. We model the cost and gain for specific enzyme activity using localization strategies based on binding to sites of intermediate specificity. While such bindings in themselves decrease the activity of the protein on its target site, they may increase protein activity if stochastic motion allows the acting protein to touch both the intermediate binding site and the specific site simultaneously. We discuss this strategy in view of recent suggestions on long non-coding RNA as a facilitator of localized activity of chromatin modifiers. PMID:22347995

  4. Anderson localization in metallic nanoparticle arrays.

    PubMed

    Mai, Zhijie; Lin, Fang; Pang, Wei; Xu, Haitao; Tan, Suiyan; Fu, Shenhe; Li, Yongyao

    2016-06-13

    Anderson localization has been observed in various types of waves, such as matter waves, optical waves and acoustic waves. Here we reveal that the effect of Anderson localization can be also induced in metallic nonlinear nanoparticle arrays excited by a random electrically driving field. We find that the dipole-induced nonlinearity results in ballistic expansion of dipole intensity during evolution; while the randomness of the external driving field can suppress such an expansion. Increasing the strength of randomness above the threshold value, a localized pattern of dipole intensity can be generated in the metallic nanoparticle arrays. By means of statistics, the mean intensity distribution of the dipoles reveals the formation of Anderson localization. We further show that the generated Anderson localization is highly confined, with its size down to the scale of incident wavelength. The reported results might facilitate the manipulations of electromagnetic fields in the scale of wavelength. PMID:27410338

  5. Collaborative Localization and Location Verification in WSNs

    PubMed Central

    Miao, Chunyu; Dai, Guoyong; Ying, Kezhen; Chen, Qingzhang

    2015-01-01

    Localization is one of the most important technologies in wireless sensor networks. A lightweight distributed node localization scheme is proposed by considering the limited computational capacity of WSNs. The proposed scheme introduces the virtual force model to determine the location by incremental refinement. Aiming at solving the drifting problem and malicious anchor problem, a location verification algorithm based on the virtual force mode is presented. In addition, an anchor promotion algorithm using the localization reliability model is proposed to re-locate the drifted nodes. Extended simulation experiments indicate that the localization algorithm has relatively high precision and the location verification algorithm has relatively high accuracy. The communication overhead of these algorithms is relative low, and the whole set of reliable localization methods is practical as well as comprehensive. PMID:25954948

  6. Localized scleroderma: clinical spectrum and therapeutic update*

    PubMed Central

    Careta, Mariana Figueiroa; Romiti, Ricardo

    2015-01-01

    Scleroderma is a rare connective tissue disease that is manifested by cutaneous sclerosis and variable systemic involvement. Two categories of scleroderma are known: systemic sclerosis, characterized by cutaneous sclerosis and visceral involvement, and localized scleroderma or morphea which classically presents benign and self-limited evolution and is confined to the skin and/or underlying tissues. Localized scleroderma is a rare disease of unknown etiology. Recent studies show that the localized form may affect internal organs and have variable morbidity. Treatment should be started very early, before complications occur due to the high morbidity of localized scleroderma. In this review, we report the most important aspects and particularities in the treatment of patients diagnosed with localized scleroderma. PMID:25672301

  7. Distillation of local purity from quantum states

    SciTech Connect

    Devetak, I.

    2005-06-15

    Recently Horodecki et al. [Phys. Rev. Lett. 90, 100402 (2003)] introduced an important quantum information processing paradigm, in which two parties sharing many copies of the same bipartite quantum state distill local pure states by means of local unitary operations assisted by a one-way (two-way) completely dephasing channel. Local pure states are a valuable resource from a thermodynamical point of view, since they allow thermal energy to be converted into work by local quantum heat engines. We give a simple information-theoretical characterization of the one-way distillable local purity, which turns out to be closely related to a previously known operational measure of classical correlations, the one-way distillable common randomness.

  8. Local-time representation of path integrals

    NASA Astrophysics Data System (ADS)

    Jizba, Petr; Zatloukal, Václav

    2015-12-01

    We derive a local-time path-integral representation for a generic one-dimensional time-independent system. In particular, we show how to rephrase the matrix elements of the Bloch density matrix as a path integral over x -dependent local-time profiles. The latter quantify the time that the sample paths x (t ) in the Feynman path integral spend in the vicinity of an arbitrary point x . Generalization of the local-time representation that includes arbitrary functionals of the local time is also provided. We argue that the results obtained represent a powerful alternative to the traditional Feynman-Kac formula, particularly in the high- and low-temperature regimes. To illustrate this point, we apply our local-time representation to analyze the asymptotic behavior of the Bloch density matrix at low temperatures. Further salient issues, such as connections with the Sturm-Liouville theory and the Rayleigh-Ritz variational principle, are also discussed.

  9. Local contrast and Pavlovian induction1

    PubMed Central

    Malone, John C.

    1976-01-01

    Two experiments examined the effects of number and similarity of stimuli on local contrast. In the first experiment, local contrast effects differed in magnitude as a function of the similarity among stimuli; greater positive local contrast appeared when stimuli were less similar, though this effect sometimes reversed for very dissimilar stimuli. In the second experiment, both positive and negative local contrast appeared transiently during the course of training a discrimination including two quite dissimilar stimuli. When two new stimuli were added, both effects reappeared in several cases. The effects remained when the discrimination was rendered more difficult by substituting a new stimulus very similar to one of the original pair. These and other data suggest that local contrast depends on the same factors that produce Pavlovian induction; in the absence of an alternative account, Pavlov's interpretation may be useful in suggesting further research that will help identify the mechanisms involved in both classical and operant discrimination learning. PMID:16811958

  10. Educating Local Audiences about Climate Change

    NASA Astrophysics Data System (ADS)

    Cullen, H. M.; Satterfield, D.; Allen, M. R.

    2014-12-01

    This talk will focus on best practices for educating local audiences about climate science and the importance of providing the larger climate context during extreme weather events, when audiences are particularly interested in the climate connection. In their role as Station Scientists, local television meteorologists serve an important function in educating viewers about climate change and its' associated impacts. Through its' Climate Matters program, Climate Central works to support local television meteorologists in their outreach efforts. Launched in 2010 with support from the National Science Foundation, the program has grown into a network that includes more than 150 weathercasters from across the country. Climate Matters delivers information on climate at the regional and local level, providing ready-to-use, broadcast quality graphics and analyses that put climate change into a local context.

  11. Single Photon Emission Local Tomography (SPELT)

    SciTech Connect

    Zeng, G.L.; Gullberg, G.T.

    1996-12-31

    Local tomography uses truncated projection data to reconstruct a region of interest, and is important in medical imaging and industrial non-destructive evaluation using micro X-ray CT. The popular filtered backprojection (FBP) algorithm does not reconstruct a reliable image, which varies with the degree and location of truncation due to its global convolution kernel. A typical local tomography method uses a second derivative local operator to replace the global convolution kernel in the filtered backprojection algorithm (LFBP). By using a local filter, the reconstructed region depends only on the local projections. The singularities (edges) are preserved, but the exact image value cannot be recovered. This paper, using the data consistency conditions, developed a pre-processing technique that uses the FBP algorithm, which outperforms direct FBP and LFBP.

  12. Scale-locality of magnetohydrodynamic turbulence

    SciTech Connect

    Aluie, Hussein; Eyink, Gregory L

    2009-01-01

    We investigate the scale-locality of cascades of conserved invariants at high kinetic and magnetic Reynolds numbers in the 'inertial-inductive range' of magnetohydrodynamic (MHD) turbulence, where velocity and magnetic field increments exhibit suitable power-law scaling. We prove that fluxes of total energy and cross-helicity - or, equivalently, fluxes of Elsaesser energies - are dominated by the contributions of local triads. Corresponding spectral transfers are also scale-local when defined using octave wavenumber bands. Flux and transfer of magnetic helicity may be dominated by nonlocal triads. The magnetic stretching term also may be dominated by non-local triads but we prove that it can convert energy only between velocity and magnetic modes at comparable scales. We explain the disagreement with numerical studies that have claimed conversion non locally between disparate scales. We present supporting data from a 1024{sup 3} simulation of forced MHD turbulence.

  13. Localization of BRCA1 protein in breast cancer tissue and cell lines with mutations

    PubMed Central

    2013-01-01

    Background The breast and ovarian cancer susceptibility gene (BRCA1) encodes a tumor suppressor. The BRCA1 protein is found primarily in cell nuclei and plays an important role in the DNA damage response and transcriptional regulation. Deficiencies in DNA repair capabilities have been associated with higher histopathological grade and worse prognosis in breast cancer. Methods In order to investigate the subcellular distribution of BRCA1 in tumor tissue we randomly selected 22 breast carcinomas and tested BRCA1 protein localization in frozen and contiguous formalin-fixed, paraffin embedded (FFPE) tissue, using pressure cooker antigen-retrieval and the MS110 antibody staining. To assess the impact of BRCA1 germline mutations on protein localization, we retrospectively tested 16 of the tumor specimens to determine whether they contained the common Ashkenazi Jewish founder mutations in BRCA1 (185delAG, 5382insC), and BRCA2 (6174delT). We also compared co-localization of BRCA1 and nucleolin in MCF7 cells (wild type) and a mutant BRCA1 cell line, HCC1937 (5382insC). Results In FFPE tissue, with MS110 antibody staining, we frequently found reduced BRCA1 nuclear staining in breast tumor tissue compared to normal tissue, and less BRCA1 staining with higher histological grade in the tumors. However, in the frozen sections, BRCA1 antibody staining showed punctate, intra-nuclear granules in varying numbers of tumor, lactating, and normal cells. Two mutation carriers were identified and were confirmed by gene sequencing. We have also compared co-localization of BRCA1 and nucleolin in MCF7 cells (wild type) and a mutant BRCA1 cell line, HCC1937 (5382insC) and found altered sub-nuclear and nucleolar localization patterns consistent with a functional impact of the mutation on protein localization. Conclusions The data presented here support a role for BRCA1 in the pathogenesis of sporadic and inherited breast cancers. The use of well-characterized reagents may lead to further

  14. Guidelines for Preservation, Conservation, and Restoration of Local History and Local Genealogical Materials.

    ERIC Educational Resources Information Center

    RQ, 1993

    1993-01-01

    Presents guidelines adopted by the American Library Association (ALA) relating to the preservation, conservation, and restoration of local history and local genealogical materials. Topics addressed include assessing preservation needs; developing a plan; choosing appropriate techniques, including microduplication, photoduplication, electronic…

  15. On Local Boundary CFT and Non-Local CFT on the Boundary

    NASA Astrophysics Data System (ADS)

    Rehren, Karl-Henning

    The holographic relation between local boundary conformal quantum field theories (BCFT) and their non-local boundary restrictions is reviewed, and non-vacuum BCFT's, whose existence was conjectured previously, are constructed. (Based on joint work [18] with R. Longo.)

  16. GEOPHYSICS, ASTRONOMY, AND ASTROPHYSICS: Nonlinear Local Lyapunov Exponent and Quantification of Local Predictability

    NASA Astrophysics Data System (ADS)

    Ding, Rui-Qiang; Li, Jian-Ping; Ha, Kyung-Ja

    2008-05-01

    Nonlinear local Lyapunov exponent (NLLE) is applied to quantitatively determine the local predictability limit of chaotic systems. As an example, we find that the local predictability limit of Henon attractor varies considerably with time, and some underlying phase-spatial structure does not appear. The local predictability limit of initially adjacent points in phase space may be completely different. This will cause difficulties in making the long-time analogue forecast.

  17. Centro para la Salud Mundial (CGH) del NCI

    Cancer.gov

    El Centro para la Salud Mundial (CGH) del NCI coordina actividades de investigación y trabaja con socios nacionales e internacionales para comprender y enfrentar la carga que representa el cáncer a nivel mundial.

  18. Living Legacy: A Conversation with Carolina Gomez del Valle.

    ERIC Educational Resources Information Center

    Montessori Life, 1993

    1993-01-01

    Carolina Gomez del Valle has been involved in training other Montessorians in Mexico, Chile, Nicaragua, Peru, and Taiwan. This interview explores her experiences with Montessori education and describes how she has woven her religious training and Montessori philosophy together. (PAM)

  19. 88. Paso Del Norte Hotel, 115117 South El Paso St., ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    88. Paso Del Norte Hotel, 115-117 South El Paso St., south facade, west side of street - South El Paso Street Historic District, South El Paso, South Oregon & South Santa Fe Streets, El Paso, El Paso County, TX

  20. 91. Paso Del Norte Hotel, 115117 South El Paso St., ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    91. Paso Del Norte Hotel, 115-117 South El Paso St., east facade, west side of street - South El Paso Street Historic District, South El Paso, South Oregon & South Santa Fe Streets, El Paso, El Paso County, TX

  1. PASO DEL NORTE HOTEL, 115117 S. EL PASO ST., SOUTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PASO DEL NORTE HOTEL, 115-117 S. EL PASO ST., SOUTH AND EAST FACADES, WEST SIDE OF STREET - South El Paso Street Historic District, South El Paso, South Oregon & South Santa Fe Streets, El Paso, El Paso County, TX

  2. 92. Paso Del Norte Hotel, 115117 South El Paso St., ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    92. Paso Del Norte Hotel, 115-117 South El Paso St., interior, lobby rotunda - South El Paso Street Historic District, South El Paso, South Oregon & South Santa Fe Streets, El Paso, El Paso County, TX

  3. PASO DEL NORTE HOTEL, 115117 S. EL PASO ST., EAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PASO DEL NORTE HOTEL, 115-117 S. EL PASO ST., EAST FACADE, WEST SIDE OF STREET - South El Paso Street Historic District, South El Paso, South Oregon & South Santa Fe Streets, El Paso, El Paso County, TX

  4. Local School Finance in North Carolina. A Yardstick for Measuring Local Support of Our Schools.

    ERIC Educational Resources Information Center

    Public School Forum of North Carolina, Raleigh.

    This document presents the results of a Forum study of local financial support of schools. The primary objective was to devise a yardstick to measure the local effort in a way useful to both citizens and policymakers. Data on property wealth for each of the 140 local school systems in North Carolina were developed. School systems making the…

  5. Spanish as a World Language: The Interplay of Globalized Localization and Localized Globalization

    ERIC Educational Resources Information Center

    Nino-Murcia, Mercedes; Godenzzi, Juan Carlos; Rothman, Jason

    2008-01-01

    This article argues that two movements in constant interplay operate within the historical trajectory of the Spanish language: the localization that becomes globalized and the globalization that becomes localized. Equally, this article illustrates how, at the same time that Spanish is expanding in the world, new idiosyncratic and localized forms…

  6. Se evitaron casi 800 000 muertes por descenso del tabaquismo

    Cancer.gov

    Programas y estrategias de control del tabaco del siglo XX fueron responsables de la prevención de más de 795 000 muertes por cáncer de pulmón en Estados Unidos de 1975 al 2000. Si todo el tabaquismo en este país hubiera cesado después de la publicación d

  7. Estudio del sistema simbiótico AR Pavonis

    NASA Astrophysics Data System (ADS)

    Quiroga, C.; Brandi, E.; Ferrer, O.; García, L.; Barbá, R.

    Se presenta un estudio espectroscópico y polarimétrico de la binaria eclipsante AR Pavonis a partir de observaciones obtenidas con el telescopio de 2.15 m. del CASLEO (San Juan). El estudio de la naturaleza del sistema se realizó a través del análisis de algunos espectros reunidos entre los años 1990 y 1995 y de datos polarimétricos correspondientes al intervalo 1995 y 1997. El análisis espectroscópico indica que AR Pav está compuesta por una gigante roja M3.7 y una componente caliente compacta, con una temperatura mayor a 90000 K y una luminosidad del orden de 500Lsolar. A lo largo del período orbital, las variaciones observadas en flujo y en velocidades radiales, reflejan que las emisiones permitidas se forman en una región que rodea la componente caliente. El estudio de la polarización lineal de AR Pav indica que además de una componente interestelar, existe una componente intrínseca del sistema que varía temporalmente y con la longitud de onda de la luz polarizada. El distinto comportamiento del grado de polarización y del ángulo de posición observado en fases diferentes, sugiere que distintos mecanismos pueden estar actuando, dependiendo de la región de scattering observado a lo largo de la línea de la visual.

  8. 65. Photographer unknown March 1931 DEL NORTE COUNTY, SECTION B, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    65. Photographer unknown March 1931 DEL NORTE COUNTY, SECTION B, HIGHWAY 1, 1-DN-1-B #66A, STA. 166.0+00 WIDENED ROADBED BEFORE COVERING LOG CRIB, 3-31. BACK READS: WIDENING ROAD BED WITH LOGS, APPROX 30 SQUARE & 60 LONG ON DN-1 SEC B STA 156+. Stamped office copy, - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  9. New local duals in eternal inflation

    NASA Astrophysics Data System (ADS)

    Bousso, Raphael; Mainemer Katz, Dan

    2012-10-01

    Global-local duality is the equivalence of seemingly different regulators in eternal inflation. For example, the light-cone time cutoff (a global measure, which regulates time) makes the same predictions as the causal patch (a local measure that cuts off space). We show that global-local duality is far more general. It rests on a redundancy inherent in any global cutoff: at late times, an attractor regime is reached, characterized by the unlimited exponential self-reproduction of a certain fundamental region of spacetime. An equivalent local cutoff can be obtained by restricting to this fundamental region. We derive local duals to several global cutoffs of interest. The new scale factor cutoff is dual to the short fat geodesic, a geodesic of fixed infinitesimal proper width. Vilenkin’s comoving apparent horizon cutoff is equivalent to the Hubbletube, whose width is proportional to the local Hubble volume. The famous youngness problem of the proper time cutoff can be readily understood by considering its local dual, the incredible shrinking geodesic.

  10. Disentangling collective trends from local dynamics.

    PubMed

    Barthélemy, Marc; Nadal, Jean-Pierre; Berestycki, Henri

    2010-04-27

    A single social phenomenon (such as crime, unemployment, or birthrate) can be observed through temporal series corresponding to units at different levels (i.e., cities, regions, and countries). Units at a given local level may follow a collective trend imposed by external conditions, but also may display fluctuations of purely local origin. The local behavior is usually computed as the difference between the local data and a global average (e.g, a national average), a viewpoint that can be very misleading. We propose here a method for separating the local dynamics from the global trend in a collection of correlated time series. We take an independent component analysis approach in which we do not assume a small average local contribution in contrast with previously proposed methods. We first test our method on synthetic series generated by correlated random walkers. We then consider crime rate series (in the United States and France) and the evolution of obesity rate in the United States, which are two important examples of societal measures. For the crime rates in the United States, we observe large fluctuations in the transition period of mid-70s during which crime rates increased significantly, whereas since the 80s, the state crime rates are governed by external factors and the importance of local specificities being decreasing. In the case of obesity, our method shows that external factors dominate the evolution of obesity since 2000, and that different states can have different dynamical behavior even if their obesity prevalence is similar. PMID:20385842

  11. Local Legal Infrastructure and Population Health

    PubMed Central

    Patton, Dana J.

    2012-01-01

    Objectives. We explored the association between the legal infrastructure of local public health, as expressed in the exercise of local fiscal and legislative authority, and local population health outcomes. Methods. Our unit of analysis was public health jurisdictions with at least 100 000 residents. The dependent variable was jurisdiction premature mortality rates obtained from the Mobilize Action Toward Community Health (MATCH) database. Our primary independent variables represented local public health’s legal infrastructure: home rule status, board of health power, county government structure, and type of public health delivery system. Several control variables were included. We used a regression model to test the relationship between the varieties of local public health legal infrastructure identified and population health status. Results. The analyses suggested that public health legal infrastructure, particularly reformed county government, had a significant effect on population health status as a mediator of social determinants of health. Conclusions. Because states shape the legal infrastructure of local public health through power-sharing arrangements, our findings suggested recommendations for state legislation that positions local public health systems for optimal impact. Much more research is needed to elucidate the complex relationships among law, social capital, and population health status. PMID:22897523

  12. Localization of airborne pure tones by pinnipeds

    NASA Astrophysics Data System (ADS)

    Holt, Marla M.; Schusterman, Ronald J.; Southall, Brandon L.; Kastak, David

    2001-05-01

    Although all pinnipeds communicate acoustically in air, most previous research on sound localization has been done under water. We have recently shown that several pinniped species localize aerial broadband signals as well as some terrestrial carnivores [Holt et al., J. Acoust. Soc. Am. 113 (2003)]. However, it is unclear which frequencies are particularly important for localization in these animals. In this study, we tested a harbor seal (Phoca vitulina) and a California sea lion (Zalophus californianus) in a hemianechoic chamber at frequencies ranging between 0.8 and 20 kHz. A left/right procedure was used to measure minimum audible angles (MAAs) corresponding to 75%-correct discrimination. MAAs ranged from approximately 4 to 13 deg in both subjects, with the largest MAAs or poorest acuity measured at the intermediate frequencies tested. These results are consistent with the duplex theory of sound localization in that low-frequency sounds appear to be localized on the basis of interaural time differences, while high-frequency sounds appear to be localized on the basis of interaural intensity differences. Testing with a northern elephant seal (Mirounga angustirostris) will provide further insight on the use of binaural cues and head-size effects with respect to localization in pinnipeds.

  13. Is Localized Scleroderma Caused by Borrelia burgdorferi?

    PubMed

    Zinchuk, Alexander N; Kalyuzhna, Lidiya D; Pasichna, Iryna A

    2016-09-01

    Despite considerable achievements in the study of localized scleroderma, the etiology of the disease has not been investigated completely. Borrelia burgdorferi-the agent of Lyme disease-is suggested to be one of the possible etiological factors of localized scleroderma. However, among scientists, this hypothesis is quite controversial. We have conducted investigations of the level of IgM and IgG class antibodies to B. burgdorferi in the serum of patients with localized scleroderma. To rationally substantiate the role of B. burgdorferi in the occurrence of localized scleroderma, thirty-two patients with localized scleroderma treated at an in-patient department were examined. The level of anti-Borrelia antibodies was determined in ELISA. Diagnostic levels of IgM and/or IgG were detected in 18.8% of patients with localized scleroderma, which is more than in the population (p < 0.01). Positive levels of anti-Borrelia antibodies in patients with localized scleroderma confirm the borreliosis nature of the disease, requiring conduction of complex antimicrobial treatment. PMID:27387068

  14. Local aggregation characteristics of microscale blood flows

    NASA Astrophysics Data System (ADS)

    Kaliviotis, Efstathios; Sherwood, Joseph M.; Dusting, Jonathan; Balabani, Stavroula

    2015-11-01

    Erythrocyte aggregation (EA) is an important aspect of microvascular flows affecting blood flow and viscosity. Microscale blood flows have been studied extensively in recent years using computational and microfluidic based approaches. However, the relationship between the local structural characteristics of blood and the velocity field has not been quantified. We report simultaneous measurements of the local velocity, aggregation and haematocrit distributions of human erythrocytes flowing in a microchannel. EA was induced using Dextran and flows were imaged using brightfield microscopy. Local aggregation characteristics were investigated using statistical and edge-detection image processing techniques while velocity profiles were obtained using PIV algorithms. Aggregation intensity was found to strongly correlate with local variations in velocity in both the central and wall regions of the channel. The edge detection method showed that near the side wall large aggregates are associated with high local velocities and low local shear rates. In the central region large aggregates occurred in regions of low velocity and high erythrocyte concentration. The results demonstrate the combined effect of haematocrit and velocity distributions on local aggregation characteristics.

  15. Local thermoelectric probes of nonequilibrium quantum systems

    NASA Astrophysics Data System (ADS)

    Stafford, Charles

    A theory of local temperature and voltage measurement in an interacting quantum system far from equilibrium is developed. We prove that a steady-state measurement by a floating thermoelectric probe is unique if it exists. Furthermore, we show that a solution exists provided there is no net local population inversion. In the case of population inversion, the system may be assigned a (unique) negative temperature. An expression for the local entropy of a nonequilibrium quantum system is introduced that, together with the local temperature and voltage, allows for a complete analysis of the local thermodynamics of the thermoelectric processes in the system. The Clausius form of the second law and the third law are shown to hold exactly locally, while the zeroth and first laws are shown to be valid to leading order in the Sommerfeld expansion. The local quantum thermodynamics underlying the enhancement of thermoelectricity by quantum interference is discussed. Work supported by the U.S. Department of Energy, Office of Science, Award No. DE-SC0006699.

  16. Local and gauge invariant observables in gravity

    NASA Astrophysics Data System (ADS)

    Khavkine, Igor

    2015-09-01

    It is well known that general relativity (GR) does not possess any non-trivial local (in a precise standard sense) and diffeomorphism invariant observable. We propose a generalized notion of local observables, which retain the most important properties that follow from the standard definition of locality, yet is flexible enough to admit a large class of diffeomorphism invariant observables in GR. The generalization comes at a small price—that the domain of definition of a generalized local observable may not cover the entire phase space of GR and two such observables may have distinct domains. However, the subset of metrics on which generalized local observables can be defined is in a sense generic (its open interior is non-empty in the Whitney strong topology). Moreover, generalized local gauge invariant observables are sufficient to separate diffeomorphism orbits on this admissible subset of the phase space. Connecting the construction with the notion of differential invariants gives a general scheme for defining generalized local gauge invariant observables in arbitrary gauge theories, which happens to agree with well-known results for Maxwell and Yang-Mills theories.

  17. On locally and nonlocally related potential systems

    NASA Astrophysics Data System (ADS)

    Cheviakov, Alexei F.; Bluman, George W.

    2010-07-01

    For any partial differential equation (PDE) system, a local conservation law yields potential equations in terms of some potential variable, which normally is a nonlocal variable. The current paper examines situations when such a potential variable is a local variable, i.e., is a function of the independent and dependent variables of a given PDE system, and their derivatives. In the case of two independent variables, a simple necessary and sufficient condition is presented for the locality of such a potential variable, and this is illustrated by several examples. As a particular example, two-dimensional reductions of equilibrium equations for fluid and plasma dynamics are considered. It is shown that such reductions with respect to helical, axial, and translational symmetries have conservation laws which yield local potential variables. This leads to showing that the well-known Johnson-Frieman-Kruskal-Oberman (JFKO) and Bragg-Hawthorne (Grad-Shafranov) equations are locally related to the corresponding helically and axially symmetric PDE systems of fluid/plasma dynamics. For the axially symmetric case, local symmetry classifications and arising invariant solutions are compared for the original PDE system and the Bragg-Hawthorne (potential) equation. The potential equation is shown to have additional symmetries, denoted as restricted symmetries. Restricted symmetries leave invariant a family of solutions of a given PDE system but not the whole solution manifold, and hence are not symmetries of the given PDE system. Corresponding reductions are shown to yield solutions, which are not obtained as invariant solutions from local symmetry reduction.

  18. Localization of eigenfunctions in the stadium billiard

    SciTech Connect

    Bies, W. E.; Kaplan, L.; Haggerty, M. R.; Heller, E. J.

    2001-06-01

    We present a systematic survey of scarring and symmetry effects in the stadium billiard. The localization of individual eigenfunctions in Husimi phase space is studied first, and it is demonstrated that on average there is more localization than can be accounted for by random-matrix theory, even after removal of bouncing-ball states and visible scars. A major point of the paper is that symmetry considerations, including parity and time-reversal symmetries, enter to influence the total amount of localization. The properties of the local density of states are also investigated, as a function of phase space location. Aside from the bouncing-ball region of phase space, excess localization is found on short periodic orbits and along certain symmetry-related lines; the origin of all these sources of localization is discussed quantitatively and comparison is made with analytical predictions. Scarring is observed to be present in all the energy ranges considered. In light of our results, the excess localization in individual eigenstates is interpreted as being primarily due to symmetry effects.

  19. Holocene paleoclimate characterization in Lago Fagnano (Tierra del Fuego) using sedimentary, physical and geochemical proxies

    NASA Astrophysics Data System (ADS)

    Vizcaino Marti, A.; Dunbar, R. B.; Wahl, D.; Moy, C. M.; Mucciarone, D. A.; Anderson, L.; Guilderson, T. P.

    2010-12-01

    Tierra del Fuego is the world's southernmost landmass outside of Antarctica. Two features of ocean circulation control the climate of Tierra del Fuego: the Southern Ocean circumpolar flow and the South Pacific Gyre. Together with Patagonia, Tierra del Fuego is the only terrestrial region directly influenced by the southern hemisphere westerly winds. This region is also a tectonically active area affected by volcanic and seismic activity related to South American and Scotia-Antarctic plate boundaries. Accommodated along the Magallanes-Fagnano fault system, as part of the plate boundary, the Lago Fagnano is the largest lake in Tierra del Fuego. This E-W trending lake is 100 km long and 5-15 km wide. Our investigations were carried out on the upper 4 meters of an 8.4 m long piston core obtained at 69 m water depth in Bahía Grande (LF06-PC8); a southwestern lake sub-basin separated from the main lake by a shallow sill. Our studies are based on the integration of sediment description, physical properties, pollen, and geochemical analyses including C and N isotopes (1cm interval) and XRF scan (1mm interval). The age model for the core is based on radiocarbon ages and tephrochronology. Additionally, a 800 km long grid of high resolution seismic profiles support the sedimentary analyses and allow the correlation with other cores from within the lake basin. LF06-PC8 yields continuous and high accumulation-rate sedimentary sections for Lago Fagnano. The presented sediment record corresponds to a laminated hemipelagite with presence of a single but complex mass transport deposit interval. An accurate sedimentological interpretation of the core together with the radiocarbon ages and tephra dates allow to identify and characterize the main sedimentary processes occurring in the lake over the last 8 kyr. In addition, proxy data (C and N isotopes and XRF scan data) from the laminated hemipelagic interval provide a reliable record of past variability in the westerly wind field as

  20. Can EPR non-locality be geometrical?

    SciTech Connect

    Ne`eman, Y. |; Botero, A.

    1995-10-01

    The presence in Quantum Mechanics of non-local correlations is one of the two fundamentally non-intuitive features of that theory. The non-local correlations themselves fall into two classes: EPR and Geometrical. The non-local characteristics of the geometrical type are well-understood and are not suspected of possibly generating acausal features, such as faster-than-light propagation of information. This has especially become true since the emergence of a geometrical treatment for the relevant gauge theories, i.e. Fiber Bundle geometry, in which the quantum non-localities are seen to correspond to pure homotopy considerations. This aspect is reviewed in section 2. Contrary-wise, from its very conception, the EPR situation was felt to be paradoxical. It has been suggested that the non-local features of EPR might also derive from geometrical considerations, like all other non-local characteristics of QM. In[7], one of the authors was able to point out several plausibility arguments for this thesis, emphasizing in particular similarities between the non-local correlations provided by any gauge field theory and those required by the preservation of the quantum numbers of the original EPR state-vector, throughout its spatially-extended mode. The derivation was, however, somewhat incomplete, especially because of the apparent difference between, on the one hand, the closed spatial loops arising in the analysis of the geometrical non-localities, from Aharonov-Bohm and Berry phases to magnetic monopoles and instantons, and on the other hand, in the EPR case, the open line drawn by the positions of the two moving decay products of the disintegrating particle. In what follows, the authors endeavor to remove this obstacle and show that as in all other QM non-localities, EPR is somehow related to closed loops, almost involving homotopy considerations. They develop this view in section 3.

  1. Ras trafficking, localization and compartmentalized signalling

    PubMed Central

    Prior, Ian A.; Hancock, John F.

    2012-01-01

    Ras proteins are proto-oncogenes that are frequently mutated in human cancers. Three closely related isoforms, HRAS, KRAS and NRAS, are expressed in all cells and have overlapping but distinctive functions. Recent work has revealed how differences between the Ras isoforms in their trafficking, localization and protein-membrane orientation enable signalling specificity to be determined. We review the various strategies used to characterize compartmentalized Ras localization and signalling. Localization is an important contextual modifier of signalling networks and insights from the Ras system are of widespread relevance for researchers interested in signalling initiated from membranes. PMID:21924373

  2. Requirements for inhibition of localized corrosion

    SciTech Connect

    Gunaltun, Y.M.; Chevrot, T.

    1999-11-01

    Localized corrosion is the principal cause of line failure when corrosion is internal. As the inhibition is the most common way to control corrosion in wet gas and oil production lines, the inhibitor should be able to control localized corrosion in all cases where it may occur. Therefore, inhibitor selection philosophy should be based on this approach. Laboratory and field evaluation of corrosion inhibitors showed that some products are almost 100% efficient in preventing localized corrosion if their concentration in the water phase is above a threshold value. The main uncertainty, which then remains, is the inhibitor availability at the pipe surface.

  3. Anomalous Hall effect in localization regime

    NASA Astrophysics Data System (ADS)

    Wu, Lin; Zhu, Kai; Yue, Di; Tian, Yuan; Jin, Xiaofeng

    2016-06-01

    The anomalous Hall effect in the ultrathin film regime is investigated in Fe(001)(1-3 nm) films epitaxial on MgO(001). The logarithmic localization correction to longitudinal resistivity and anomalous Hall resistivity are observed at low temperature. We identify that the coefficient of skew scattering has a reduction from metallic to localized regime, while the contribution of side jump has inconspicuous change except for a small drop below 10 K. Furthermore, we discover that the intrinsic anomalous Hall conductivity decreases with the reduction of thickness below 2 nm. Our results provide unambiguous experimental evidence to clarify the problem of localization correction to the anomalous Hall effect.

  4. Recognition and localization of intracranial disease.

    PubMed

    Bagley, R S

    1996-07-01

    Clinical recognition and localization of disease within the nervous system is paramount to effective diagnosis and treatment of animals with neurologic disease. Thorough examination of the nervous system is based upon an understanding of normal neuroanatomy and physiology. Once a disease process is established to involve the nervous system, localization of the abnormalities within the nervous system is imperative for formulation of a differential diagnosis and diagnostic plan. This article reviews important aspects of the neurologic examination that lead to neuroanatomical localization. PMID:8813746

  5. Local transport measurements on epitaxial graphene

    NASA Astrophysics Data System (ADS)

    Baringhaus, J.; Edler, F.; Neumann, C.; Stampfer, C.; Forti, S.; Starke, U.; Tegenkamp, C.

    2013-09-01

    Growth of large-scale graphene is still accompanied by imperfections. By means of a four-tip scanning tunneling and electron microscope (4-tip STM/SEM), the local structure of graphene grown on SiC(0001) was correlated with scanning electron microscope images and spatially resolved transport measurements. The systematic variation of probe spacings and substrate temperature has clearly revealed two-dimensional transport regimes of Anderson localization as well as of diffusive transport. The detailed analysis of the temperature dependent data demonstrates that the local on-top nano-sized contacts do not induce significant strain to the epitaxial graphene films.

  6. Analysis of GPCR Localization and Trafficking

    PubMed Central

    Hislop, James N.; von Zastrow, Mark

    2016-01-01

    Localization and trafficking of G protein-coupled receptors (GPCRs) is increasingly recognized to play a fundamental role in receptor-mediated signaling and its regulation. Individual receptors, including closely homologous subtypes with otherwise similar functional properties, can differ considerably in their membrane trafficking properties. In this chapter, we describe several approaches for experimentally assessing the subcellular localization and trafficking of selected GPCRs. Firstly, we describe a flexible method for receptor localization using fluorescence microscopy. We then describe two complementary approaches, using fluorescence flow cytometry and surface biotinylation, for examining receptor internalization and trafficking in the endocytic pathway. PMID:21607873

  7. Modeling of Protein Subcellular Localization in Bacteria

    NASA Astrophysics Data System (ADS)

    Xu, Xiaohua; Kulkarni, Rahul

    2006-03-01

    Specific subcellular localization of proteins is a vital component of important bacterial processes: e.g. the Min proteins which regulate cell division in E. coli and Spo0J-Soj system which is critical for sporulation in B. subtilis. We examine how the processes of diffusion and membrane attachment contribute to protein subcellular localization for the above systems. We use previous experimental results to suggest minimal models for these processes. For the minimal models, we derive analytic expressions which provide insight into the processes that determine protein subcellular localization. Finally, we present the results of numerical simulations for the systems studied and make connections to the observed experiemental phenomenology.

  8. Many-body localization in dipolar systems.

    PubMed

    Yao, N Y; Laumann, C R; Gopalakrishnan, S; Knap, M; Müller, M; Demler, E A; Lukin, M D

    2014-12-12

    Systems of strongly interacting dipoles offer an attractive platform to study many-body localized phases, owing to their long coherence times and strong interactions. We explore conditions under which such localized phases persist in the presence of power-law interactions and supplement our analytic treatment with numerical evidence of localized states in one dimension. We propose and analyze several experimental systems that can be used to observe and probe such states, including ultracold polar molecules and solid-state magnetic spin impurities. PMID:25541771

  9. Engaging Students through Mapping Local History

    PubMed Central

    Mitchell, Katharyne; Elwood, Sarah

    2015-01-01

    This article argues that the integration of local history and geography through collaborative digital mapping can lead to greater interest in civic participation by early adolescent learners. In the study, twenty-nine middle school students were asked to research, represent, and discuss local urban sites of historical significance on an interactive Web platform. As students learned more about local community events, people, and historical forces, they became increasingly engaged with the material and enthusiastic about making connections to larger issues and processes. In the final session, students expressed interest in participating in their own communities through joining nonprofit organizations and educating others about community history and daily life. PMID:25635145

  10. Quantum Localization of the Kicked Rydberg Atom

    SciTech Connect

    Yoshida, S.; Reinhold, C. O.; Physics Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6373 ; Burgdoerfer, J.; Physics Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6373; Institute for Theoretical Physics, Vienna University of Technology, A1040 Vienna,

    2000-03-20

    We investigate the quantum localization of the one-dimensional Rydberg atom subject to a unidirectional periodic train of impulses. For high frequencies of the train the classical system becomes chaotic and leads to fast ionization. By contrast, the quantum system is found to be remarkably stable. We find this quantum localization to be directly related to the existence of ''scars'' of the unstable periodic orbits of the system. The localization length is given by the energy excursion along the periodic orbits. (c) 2000 The American Physical Society.

  11. Demagnetizing effect in local magnetic measurements

    NASA Astrophysics Data System (ADS)

    Wen, Bo; Subedi, Pradeep; Yeshurun, Yosi; Sarachik, Myriam; Kent, Andrew; Millis, Andrew; Pardo, Enric; Mukherjee, Shreya; Christou, George

    2012-02-01

    It is well-known that magnetic measurements need to be corrected for the presence of demagnetizing fields that depend on both χ and the sample shape. Calculated demagnetization factors are generally available in tabular form for standard shapes, such as ellipsoids, spheres, and parallelopipeds, thereby providing corrections for measurements of the magnetization of the entire sample. However, appropriate corrections are not available for measurements obtained by local probes, such as micron-size Hall sensors. In this talk we present calculations of the local demagnetizing field profile and show how these results can be applied to interpret local magnetization measurements in Mn12-ac.

  12. Software for neutrino acoustic detection and localization

    NASA Astrophysics Data System (ADS)

    Bouhadef, B.

    2009-06-01

    The evidence of the existing of UHE (E>10eV) cosmic rays and its possible connection to UHE neutrino suggests the building of an acoustic telescope for neutrino, exploiting thermo-acoustic effect. We present software for neutrino acoustic signal detection and localization. The main points discussed here are the sea noise model, the determination of time differences of arrival (TDOA) between hydrophones signals, the source localization algorithm, and the telescope geometry effect. The effect of TDOAs errors and telescope geometry on the localization accuracy is also discussed.

  13. Chronologic implications of new Miocene mammals from the Cura-Mallín and Trapa Trapa formations, Laguna del Laja area, south central Chile

    NASA Astrophysics Data System (ADS)

    Flynn, John J.; Charrier, Reynaldo; Croft, Darin A.; Gans, Phillip B.; Herriott, Trystan M.; Wertheim, Jill A.; Wyss, André R.

    2008-12-01

    Recent work in the central Andean Main Range of Chile near Laguna del Laja (˜37.5°S, 71°W) has produced the first mammal fossils for the region. Fossils, locally abundant and well preserved, occur patchily across a wide area southeast of the lake. Mammalian remains are derived from generally strongly folded (kilometer-scale) exposures of the locally ˜1.8 km thick, early to middle Miocene Cura-Mallín Formation; two identifiable specimens have been recovered from the overlying Trapa Trapa Formation as well. Both formations consist primarily of well-stratified (1-5 m thick layers) volcaniclastic and volcanic strata, deposited predominantly in fluviatile systems. The Cura-Mallín Formation is possibly the southern continuation of (or lateral equivalent to) the richly fossiliferous Abanico Formation mapped between ˜32°S and 36°S. Intensive sampling in a series of localities east and south of Laguna del Laja has yielded diverse faunas, in addition to radioisotopically dateable horizons. The new fossil mammal faunas represent as many as six South American Land Mammal "Ages" (SALMAs). Fossils, together with preliminary 40Ar/ 39Ar radioisotopic dates, ranging from ˜9 to 20 Ma across the exposed thickness of the Cura-Mallín Formation and into the overlying Trapa Trapa Formation, provide a robust geochronological framework for middle Cenozoic strata in the Laguna del Laja region. The sequence of directly superposed mammalian assemblages at Laguna del Laja is one of the longest in all of South America, rivaled only by the classic Gran Barranca section of Patagonian Argentina. These data illuminate the geological history of the area and its record of mammalian evolution. The potential to isotopically date these diverse faunas with high precision (error ± 0.5 Ma) presents a rare opportunity to calibrate related portions of the SALMA sequence.

  14. Extreme Environments in Tierra del Fuego, Argentina

    NASA Astrophysics Data System (ADS)

    Schultz, C.; D'Antoni, H.; Burgess, S.; Zamora, J.; Skiles, J.

    2007-12-01

    The upper timberline of the Andes Cordillera on the island of Tierra del Fuego at the tip of South America is an environment subject to extreme conditions. In order to further understand this environment, ecosystem parameters were measured within two transects of the Andes at Glaciar Martial and Cerro Guanaco. The measurements included pH, soil temperature, soil moisture, nitrogen, sodium and potassium concentration, chlorophyll absorbance, and irradiance in the ultraviolet range (200-400 nm). These data comprise a survey that serves as a baseline for an intensive research program. Chlorophyll concentration and soil data were within the range of our observations at several other sites, from Lapataia Bay on the southwestern boundary with Chile, through the eastern end of Lake Fagnano. However, unusual levels of solar irradiance were found in the open sites of both transects while those in the forest exhibited lower UV values, suggesting strong absorption and/or reflection by the forest canopy. High levels of UV radiation damage important biomolecules and may be partially responsible for the presence of life forms such as the krummholz belt in the upper timberline. These UV values may be due to the effects of global ozone depletion and the ozone hole. The low temperatures, strong winds, snow and ice-covered soil and especially the exposure to UV radiation make this area an extreme environment for life.

  15. Multi-Scale Locality-Constrained Spatiotemporal Coding for Local Feature Based Human Action Recognition

    PubMed Central

    Liu, Yu; Wang, Wei; Xu, Wei; Zhang, Maojun

    2013-01-01

    We propose a Multiscale Locality-Constrained Spatiotemporal Coding (MLSC) method to improve the traditional bag of features (BoF) algorithm which ignores the spatiotemporal relationship of local features for human action recognition in video. To model this spatiotemporal relationship, MLSC involves the spatiotemporal position of local feature into feature coding processing. It projects local features into a sub space-time-volume (sub-STV) and encodes them with a locality-constrained linear coding. A group of sub-STV features obtained from one video with MLSC and max-pooling are used to classify this video. In classification stage, the Locality-Constrained Group Sparse Representation (LGSR) is adopted to utilize the intrinsic group information of these sub-STV features. The experimental results on KTH, Weizmann, and UCF sports datasets show that our method achieves better performance than the competing local spatiotemporal feature-based human action recognition methods. PMID:24194681

  16. Nonstationary energy localization vs conventional stationary localization in weakly coupled nonlinear oscillators

    NASA Astrophysics Data System (ADS)

    Manevitch, Leonid I.; Kovaleva, Agnessa; Sigalov, Grigori

    2016-03-01

    In this paper we study the effect of nonstationary energy localization in a nonlinear conservative resonant system of two weakly coupled oscillators. This effect is alternative to the well-known stationary energy localization associated with the existence of localized normal modes and resulting from a local topological transformation of the phase portraits of the system. In this work we show that nonstationary energy localization results from a global transformation of the phase portrait. A key to solving the problem is the introduction of the concept of limiting phase trajectories (LPTs) corresponding to maximum possible energy exchange between the oscillators. We present two scenarios of nonstationary energy localization under the condition of 1:1 resonance. It is demonstrated that the conditions of nonstationary localization determine the conditions of efficient targeted energy transfer in a generating dynamical system. A possible extension to multi-particle systems is briefly discussed.

  17. Local discrimination scheme for some unitary operations

    NASA Astrophysics Data System (ADS)

    Cao, TianQing; Gao, Fei; Tian, GuoJing; Xie, ShuCui; Wen, QiaoYan

    2016-09-01

    It has been shown that for two different multipartite unitary operations U 1 and U 2, when tr( U 1 † U 2) = 0, they can always be perfectly distinguished by local operations and classical communication in the single-run scenario. However, how to find the detailed scheme to complete the local discrimination is still a fascinating problem. In this paper, aiming at some U 1 and U 2 acting on the bipartite and tripartite space respectively, especially for U 1 † U 2 locally unitary equivalent to the high dimensional X-type hermitian unitary matrix V with tr V = 0, we put forward the explicit local distinguishing schemes in the single-run scenario.

  18. Induction therapy for locally advanced thymoma.

    PubMed

    Riely, Gregory J; Huang, James

    2010-10-01

    Thymomas are the most frequently encountered tumors of the mediastinum and often present with either localized or locally advanced disease. The prognosis in thymoma has been consistently shown to correspond to the invasiveness of the tumor (as represented by the Masaoka stage of the tumor) and the completeness of surgical resection. Because treatment with a variety of different chemotherapy regimens has demonstrated radiographic response rates greater than 50% in patients with advanced thymoma, a number of investigators have explored the use of preoperative (induction, neoadjuvant) therapy for patients with locally advanced thymoma. In this review, we summarize the published experience with preoperative therapy for thymoma and discuss ongoing clinical trials exploring multimodality therapy for treatment of locally advanced thymoma. PMID:20859127

  19. Local density dependent potential for compressible mesoparticles

    NASA Astrophysics Data System (ADS)

    Faure, Gérôme; Maillet, Jean-Bernard; Stoltz, Gabriel

    2014-03-01

    This work proposes a coarse grained description of molecular systems based on mesoparticles representing several molecules, where interactions between mesoparticles are modelled by an interparticle potential of molecular type. Since strong non-equilibrium situations over a wide range of pressure and density are targeted, the internal compressibility of the mesoparticles has to be considered. This is done by introducing a dependence of the potential on the local environment of the mesoparticles. To define local densities, we resort to a three-dimensional Voronoi tessellation instead of standard local, spherical averages. As an example, a local density dependent potential is fitted to reproduce the Hugoniot curve of a model of nitromethane over a large range of pressures and densities.

  20. Local Physical Coordinates from Symplectic Projector Method

    NASA Astrophysics Data System (ADS)

    de Andrade, M. A.; Santos, M. A.; Vancea, I. V.

    The basic arguments underlying the symplectic projector method are presented. By this method, local free coordinates on the constraint surface can be obtained for a broader class of constrained systems. Some interesting examples are analyzed.

  1. Logical operator tradeoff for local quantum codes

    NASA Astrophysics Data System (ADS)

    Haah, Jeongwan; Preskill, John

    2011-03-01

    We study the structure of logical operators in local D -dimensional quantum codes, considering both subsystem codes with geometrically local gauge generators and codes defined by geometrically local commuting projectors. We show that if the code distance is d , then any logical operator can be supported on a set of specified geometry containing d~ qubits, where d~d 1 / (D - 1) = O (n) and n is the code length. Our results place limitations on partially self-correcting quantum memories, in which at least some logical operators are protected by energy barriers that grow with system size. We also show that two-dimensional codes defined by local commuting projectors admit logical ``string'' operators and are not self correcting. NSF PHY-0803371, DOE DE-FG03-92-ER40701, NSA/ARO W911NF-09-1-0442, and KFAS.

  2. Local noise in a diffusive conductor.

    PubMed

    Tikhonov, E S; Shovkun, D V; Ercolani, D; Rossella, F; Rocci, M; Sorba, L; Roddaro, S; Khrapai, V S

    2016-01-01

    The control and measurement of local non-equilibrium configurations is of utmost importance in applications on energy harvesting, thermoelectrics and heat management in nano-electronics. This challenging task can be achieved with the help of various local probes, prominent examples including superconducting or quantum dot based tunnel junctions, classical and quantum resistors, and Raman thermography. Beyond time-averaged properties, valuable information can also be gained from spontaneous fluctuations of current (noise). From these perspective, however, a fundamental constraint is set by current conservation, which makes noise a characteristic of the whole conductor, rather than some part of it. Here we demonstrate how to remove this obstacle and pick up a local noise temperature of a current biased diffusive conductor with the help of a miniature noise probe. This approach is virtually noninvasive for the electronic energy distributions and extends primary local measurements towards strongly non-equilibrium regimes. PMID:27466216

  3. Talking Books and the Local Library

    ERIC Educational Resources Information Center

    Kamisar, Hylda; Pollet, Dorothy

    1974-01-01

    Under the administration of the Library of Congress, local and regional libraries cooperate in the talking book program by distributing books and magazines, as well as audio equipment, to the visually handicapped. (LS)

  4. Gauge field localization on brane worlds

    SciTech Connect

    Guerrero, Rommel; Rodriguez, R. Omar; Melfo, Alejandra; Pantoja, Nelson

    2010-04-15

    We consider the effects of spacetime curvature and brane thickness on the localization of gauge fields on a brane via kinetic terms induced by localized fermions. We find that in a warped geometry with an infinitely thin brane, both the infrared and the ultraviolet behavior of the electromagnetic propagator are affected, providing a more stringent bound on the brane's tension than that coming from the requirement of four-dimensional gravity on the brane. On the other hand, for a thick wall in a flat spacetime, where the fermions are localized by means of a Yukawa coupling, we find that four-dimensional electromagnetism is recovered in a region bounded from above by the same critical distance appearing in the thin case, but also from below by a new scale related to the brane's thickness and the electromagnetic couplings. This imposes very stringent bounds on the brane's thickness which seem to invalidate the localization mechanism for this case.

  5. Fiber-connected position localization sensor networks

    NASA Astrophysics Data System (ADS)

    Pan, Shilong; Zhu, Dan; Fu, Jianbin; Yao, Tingfeng

    2014-11-01

    Position localization has drawn great attention due to its wide applications in radars, sonars, electronic warfare, wireless communications and so on. Photonic approaches to realize position localization can achieve high-resolution, which also provides the possibility to move the signal processing from each sensor node to the central station, thanks to the low loss, immunity to electromagnetic interference (EMI) and broad bandwidth brought by the photonic technologies. In this paper, we present a review on the recent works of position localization based on photonic technologies. A fiber-connected ultra-wideband (UWB) sensor network using optical time-division multiplexing (OTDM) is proposed to realize high-resolution localization and moving the signal processing to the central station. A 3.9-cm high spatial resolution is achieved. A wavelength-division multiplexed (WDM) fiber-connected sensor network is also demonstrated to realize location which is independent of the received signal format.

  6. Hearing in three dimensions: Sound localization

    NASA Technical Reports Server (NTRS)

    Wightman, Frederic L.; Kistler, Doris J.

    1990-01-01

    The ability to localize a source of sound in space is a fundamental component of the three dimensional character of the sound of audio. For over a century scientists have been trying to understand the physical and psychological processes and physiological mechanisms that subserve sound localization. This research has shown that important information about sound source position is provided by interaural differences in time of arrival, interaural differences in intensity and direction-dependent filtering provided by the pinnae. Progress has been slow, primarily because experiments on localization are technically demanding. Control of stimulus parameters and quantification of the subjective experience are quite difficult problems. Recent advances, such as the ability to simulate a three dimensional sound field over headphones, seem to offer potential for rapid progress. Research using the new techniques has already produced new information. It now seems that interaural time differences are a much more salient and dominant localization cue than previously believed.

  7. Spatial Symmetries of the Local Densities

    SciTech Connect

    Rohozinski, S.; Dobaczewski, J.; Nazarewicz, Witold

    2010-01-01

    Spatial symmetries of the densities appearing in the nuclear Density Functional Theory are discussed. General forms of the local densities are derived by using methods of construction of isotropic tensor fields. The spherical and axial cases are considered.

  8. Local noise in a diffusive conductor

    PubMed Central

    Tikhonov, E. S.; Shovkun, D. V.; Ercolani, D.; Rossella, F.; Rocci, M.; Sorba, L.; Roddaro, S.; Khrapai, V. S.

    2016-01-01

    The control and measurement of local non-equilibrium configurations is of utmost importance in applications on energy harvesting, thermoelectrics and heat management in nano-electronics. This challenging task can be achieved with the help of various local probes, prominent examples including superconducting or quantum dot based tunnel junctions, classical and quantum resistors, and Raman thermography. Beyond time-averaged properties, valuable information can also be gained from spontaneous fluctuations of current (noise). From these perspective, however, a fundamental constraint is set by current conservation, which makes noise a characteristic of the whole conductor, rather than some part of it. Here we demonstrate how to remove this obstacle and pick up a local noise temperature of a current biased diffusive conductor with the help of a miniature noise probe. This approach is virtually noninvasive for the electronic energy distributions and extends primary local measurements towards strongly non-equilibrium regimes. PMID:27466216

  9. 46 CFR 172.205 - Local damage.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Subchapter O of This Chapter § 172.205 Local damage. (a) Each tankship must be shown by design calculations... heel beyond the smaller of the following angles in the final stage of flooding: (1) 30 degrees. (2)...

  10. 46 CFR 172.205 - Local damage.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Subchapter O of This Chapter § 172.205 Local damage. (a) Each tankship must be shown by design calculations... heel beyond the smaller of the following angles in the final stage of flooding: (1) 30 degrees. (2)...

  11. Localization of Waves in Merged Lattices.

    PubMed

    Alagappan, G; Png, C E

    2016-01-01

    This article describes a new two-dimensional physical topology-merged lattice, that allows dense number of wave localization states. Merged lattices are obtained as a result of merging two lattices of scatters of the same space group, but with slightly different spatial resonances. Such merging creates two-dimensional scattering "beats" which are perfectly periodic on the longer spatial scale. On the shorter spatial scale, the systematic breakage of the translational symmetry leads to strong wave scattering, and this causes the occurrences of wave localization states. Merged Lattices promises variety of localization states including tightly confined, and ring type annular modes. The longer scale perfect periodicity of the merged lattice, enables complete prediction and full control over the density of the localization states and its' quality factors. In addition, the longer scale periodicity, also allows design of integrated slow wave components. Merged lattices, thus, can be engineered easily to create technologically beneficial applications. PMID:27535096

  12. Evaluation of river restoration by local residents

    NASA Astrophysics Data System (ADS)

    Seidl, Roman; Stauffacher, Michael

    2013-10-01

    Today, river corrections aiming at better flood protection must consider ecological aspects such as "naturalness" and biodiversity. Gaining acceptance among local residents for these projects is important, since they impact local infrastructure and alter the familiar landscape. The question addressed in this paper is whether there are differences between local residents regarding the question of whether they think a river restoration project at a section of the Swiss Thur River was reasonable. We also investigate whether there are differences regarding the reasons for this evaluation, such as improved flood protection, higher perceived naturalness, increased biodiversity, and aesthetics. Results show that for farmers flood protection and naturalness are more important factors than for others and that there are differences among the local villages.

  13. Local community extraction in directed networks

    NASA Astrophysics Data System (ADS)

    Ning, Xuemei; Liu, Zhaoqi; Zhang, Shihua

    2016-06-01

    Network is a simple but powerful representation of real-world complex systems. Network community analysis has become an invaluable tool to explore and reveal the internal organization of nodes. However, only a few methods were directly designed for community-detection in directed networks. In this article, we introduce the concept of local community structure in directed networks and provide a generic criterion to describe a local community with two properties. We further propose a stochastic optimization algorithm to rapidly detect a local community, which allows for uncovering the directional modular characteristics in directed networks. Numerical results show that the proposed method can resolve detailed local communities with directional information and provide more structural characteristics of directed networks than previous methods.

  14. Local noise in a diffusive conductor

    NASA Astrophysics Data System (ADS)

    Tikhonov, E. S.; Shovkun, D. V.; Ercolani, D.; Rossella, F.; Rocci, M.; Sorba, L.; Roddaro, S.; Khrapai, V. S.

    2016-07-01

    The control and measurement of local non-equilibrium configurations is of utmost importance in applications on energy harvesting, thermoelectrics and heat management in nano-electronics. This challenging task can be achieved with the help of various local probes, prominent examples including superconducting or quantum dot based tunnel junctions, classical and quantum resistors, and Raman thermography. Beyond time-averaged properties, valuable information can also be gained from spontaneous fluctuations of current (noise). From these perspective, however, a fundamental constraint is set by current conservation, which makes noise a characteristic of the whole conductor, rather than some part of it. Here we demonstrate how to remove this obstacle and pick up a local noise temperature of a current biased diffusive conductor with the help of a miniature noise probe. This approach is virtually noninvasive for the electronic energy distributions and extends primary local measurements towards strongly non-equilibrium regimes.

  15. Visual Self-Localization with Tiny Images

    NASA Astrophysics Data System (ADS)

    Hofmeister, Marius; Erhard, Sara; Zell, Andreas

    Self-localization of mobile robots is often performed visually, whereby the resolution of the images influences a lot the computation time. In this paper, we examine how a reduction of the image resolution affects localization accuracy. We downscale the images, preserving their aspect ratio, up to a tiny resolution of 15×11 and 20×15 pixels. Our results are based on extensive tests on different datasets that have been recorded indoors by a small differential drive robot and outdoors by a flying quadrocopter. Four well-known global image features and a pixel-wise image comparison method are compared under realistic conditions such as illumination changes and translations. Our results show that even when reducing the image resolution down to the tiny resolutions above, accurate localization is achievable. In this way, we can speed up the localization process considerably.

  16. Locally-smeared operator product expansions

    SciTech Connect

    Monahan, Christopher; Orginos, Kostantinos

    2014-12-01

    We propose a "locally-smeared Operator Product Expansion" (sOPE) to decompose non-local operators in terms of a basis of locally-smeared operators. The sOPE formally connects nonperturbative matrix elements of smeared degrees of freedom, determined numerically using the gradient flow, to non-local operators in the continuum. The nonperturbative matrix elements do not suffer from power-divergent mixing on the lattice, provided the smearing scale is kept fixed in the continuum limit. The presence of this smearing scale prevents a simple connection to the standard operator product expansion and therefore requires the construction of a two-scale formalism. We demonstrate the feasibility of our approach using the example of real scalar field theory.

  17. Localized soft elasticity in liquid crystal elastomers

    NASA Astrophysics Data System (ADS)

    Ware, Taylor H.; Biggins, John S.; Shick, Andreas F.; Warner, Mark; White, Timothy J.

    2016-02-01

    Synthetic approaches to prepare designer materials that localize deformation, by combining rigidity and compliance in a single material, have been widely sought. Bottom-up approaches, such as the self-organization of liquid crystals, offer potential advantages over top-down patterning methods such as photolithographic control of crosslink density, relating to the ease of preparation and fidelity of resolution. Here, we report on the directed self-assembly of materials with spatial and hierarchical variation in mechanical anisotropy. The highly nonlinear mechanical properties of the liquid crystalline elastomers examined here enables strain to be locally reduced >15-fold without introducing compositional variation or other heterogeneities. Each domain (>=0.01 mm2) exhibits anisotropic nonlinear response to load based on the alignment of the molecular orientation with the loading axis. Accordingly, we design monoliths that localize deformation in uniaxial and biaxial tension, shear, bending and crack propagation, and subsequently demonstrate substrates for globally deformable yet locally stiff electronics.

  18. [Local invasive treatment of chronic pain].

    PubMed

    Medvedeva, L A; Zagorul'ko, O I; Gnezdilov, A V

    2014-01-01

    The literature on methods of invasive local treatment of chronic pain was analyzed. We reviewed 14 publications including meta-analyses and systematic reviews. The use of regional anesthesia conducted by anesthesiologists in pain clinics demonstrated the evidence based efficacy of different types of peridural injections of local anesthetics with steroids in patients with root pain syndromes at cervical and lumbar levels. Therapeutic blockades of the occipital nerve is effective method of treatment of cervicogenic and cluster headache as well as occipital nerve neuralgia. There are clear indications of the efficacy of local injections in primary chronic cephalgia (migraine and headache of tension). The possibility of the abortion of the pain information flow in peripheral nociceptive pathways and, as a consequence, breaking the vicious circle is emphasized. Issues on the efficacy of local injections at trigger points in the treatment of chronic pain are highlighted. PMID:24874319

  19. Complex Patterns of Local Adaptation in Teosinte

    PubMed Central

    Pyhäjärvi, Tanja; Hufford, Matthew B.; Mezmouk, Sofiane; Ross-Ibarra, Jeffrey

    2013-01-01

    Populations of widely distributed species encounter and must adapt to local environmental conditions. However, comprehensive characterization of the genetic basis of adaptation is demanding, requiring genome-wide genotype data, multiple sampled populations, and an understanding of population structure and potential selection pressures. Here, we used single-nucleotide polymorphism genotyping and data on numerous environmental variables to describe the genetic basis of local adaptation in 21 populations of teosinte, the wild ancestor of maize. We found complex hierarchical genetic structure created by altitude, dispersal events, and admixture among subspecies, which complicated identification of locally beneficial alleles. Patterns of linkage disequilibrium revealed four large putative inversion polymorphisms showing clinal patterns of frequency. Population differentiation and environmental correlations suggest that both inversions and intergenic polymorphisms are involved in local adaptation. PMID:23902747

  20. Supersonic projectile models for asynchronous shooter localization

    NASA Astrophysics Data System (ADS)

    Kozick, Richard J.; Whipps, Gene T.; Ash, Joshua N.

    2011-06-01

    In this work we consider the localization of a gunshot using a distributed sensor network measuring time differences of arrival between a firearm's muzzle blast and the shockwave induced by a supersonic bullet. This so-called MB-SW approach is desirable because time synchronization is not required between the sensors, however it suffers from increased computational complexity and requires knowledge of the bullet's velocity at all points along its trajectory. While the actual velocity profile of a particular gunshot is unknown, one may use a parameterized model for the velocity profile and simultaneously fit the model and localize the shooter. In this paper we study efficient solutions for the localization problem and identify deceleration models that trade off localization accuracy and computational complexity. We also develop a statistical analysis that includes bias due to mismatch between the true and actual deceleration models and covariance due to additive noise.