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1

Microfluidic serial dilution ladder.  

PubMed

Serial dilution is a fundamental procedure that is common to a large number of laboratory protocols. Automation of serial dilution is thus a valuable component for lab-on-a-chip systems. While a handful of different microfluidic strategies for serial dilution have been reported, approaches based on continuous flow mixing inherently consume larger amounts of sample volume and chip real estate. We employ valve-driven circulatory mixing to address these issues and also introduce a novel device structure to store each stage of the dilution process. The dilution strategy is based on sequentially mixing the rungs of a ladder structure. We demonstrate a 7-stage series of 1?:?1 dilutions with R(2) equal to 0.995 in an active device area of 1 cm(2). PMID:24231765

Ahrar, Siavash; Hwang, Michelle; Duncan, Philip N; Hui, Elliot E

2014-01-01

2

Dispersion serial dilution methods using the gradient diluter device.  

PubMed

A solute aspirated into a prefilled tube of diluent undergoes a dilution effect known as dispersion. Traditionally the effects of dispersion have been considered a negative consequence of using liquid-filled fixed-tip liquid handlers. We present a novel device and technique that utilizes the effects of dispersion to the benefit of making dilutions. The device known as the Gradient Diluter extends the dilution range of practical serial dilutions to six orders of magnitude in final volumes as low as 10??L. Presented are the device, dispersion methods, and validation tests using fluorescence detection of sulforhodamine and the high-performance liquid chromatography/ultraviolet detection of furosemide. In addition, a T-cell inhibition assay of a relevant downstream protein is used to demonstrate IC(50) curves made with the Gradient Diluter compare favorably with those generated by hand. PMID:22364546

Walling, Leslie; Schulz, Craig; Johnson, Michael

2012-12-01

3

Implementing Inquiry-Based Learning in Teaching Serial Dilutions  

ERIC Educational Resources Information Center

The 5E model of inquiry-based learning was incorporated into a sophomore-level microbiology laboratory to increase student understanding of serial dilutions, a concept that is often difficult for most students to comprehend. Quantitative and qualitative assessments were conducted during the semester to determine the value of this approach for…

Walker, Candace L.; McGill, Michael T.; Buikema, Arthur L., Jr.; Stevens, Ann M.

2008-01-01

4

ON-DEMAND SERIAL DILUTION USING QUANTIZED NANO/PICOLITER-SCALE DROPLETS  

SciTech Connect

This paper describes a fully automated droplet-based microfluidic device for on-demand serial dilution that is capable of achieving a dilution ratio of >6000 (concentration ranges from 1 mM to 160nM) over 35 nanoliter-scale droplets. This serial diluter can be applied to high throughput and label-free kinetic assays by integrating with our previously developed on-demand droplet-based microfluidic with mass spectrometry detection.

Jambovane, Sachin R.; Prost, Spencer A.; Sheen, Allison M.; Magnuson, Jon K.; Kelly, Ryan T.

2014-10-29

5

Biometrics 60, 407417 Bayesian Analysis of Serial Dilution Assays  

E-print Network

laboratory data on cockroach allergens measured in house dust samples. Our estimates are much more accurate of measurements versus dilutions from a single plate (assays of the cockroach allergen Bla g1), for the standards

Gelman, Andrew

6

Multicenter comparison of the ISO standard 20776-1 and the serial 2-fold dilution procedures to dilute hydrophilic and hydrophobic antifungal agents for susceptibility testing.  

PubMed

A multicenter study was conducted to assess the accuracy of the ISO standard 20776-1 and the serial 2-fold dilution procedures for antifungal susceptibility testing. Fluconazole trays can be accurately prepared by following ISO and serial dilution schemes. However, itraconazole trays showed a significant lack of reproducibility that was independent of which method was followed. PMID:20220174

Gomez-Lopez, Alicia; Arendrup, Maiken Cavling; Lass-Floerl, Cornelia; Rodriguez-Tudela, Juan-Luis; Cuenca-Estrella, Manuel

2010-05-01

7

Multicenter Comparison of the ISO Standard 20776-1 and the Serial 2-Fold Dilution Procedures To Dilute Hydrophilic and Hydrophobic Antifungal Agents for Susceptibility Testing ? †  

PubMed Central

A multicenter study was conducted to assess the accuracy of the ISO standard 20776-1 and the serial 2-fold dilution procedures for antifungal susceptibility testing. Fluconazole trays can be accurately prepared by following ISO and serial dilution schemes. However, itraconazole trays showed a significant lack of reproducibility that was independent of which method was followed. PMID:20220174

Gomez-Lopez, Alicia; Arendrup, Maiken Cavling; Lass-Floerl, Cornelia; Rodriguez-Tudela, Juan-Luis; Cuenca-Estrella, Manuel

2010-01-01

8

Establishing quality assurance criteria for serial dilution operations on liquid-handling equipment.  

PubMed

Since the advent of high-throughput screening (HTS) in the early 1990s, parallel multichannel liquid handlers have become a mainstay in every drug discovery setting. Although several peer-reviewed publications have discussed methods and criteria for stamping multiwell copies, there is very little information about establishing a standard operating procedure (SOP) for standard (microliter-level) serial dilutions of compounds used in dose-response experiments. The authors discuss the 4 main criteria any serial dilution process must pass (accuracy, precision, fold dilution, and outliers) and the process for establishing thresholds for all of these values in a compound management or biological screening laboratory. The thresholds need to be both low enough to be acceptable from a biological potency variability perspective and high enough to allow the instruments to pass the quality assurance (QA) analysis on a regular basis. In this article, the authors suggest suitable thresholds arrived at by a variety of methods, including trend analysis of QA data, survey questionnaire from the main stakeholders (screening scientists, chemists), and published criteria for single-shot stamping. A mathematical analysis of the effect of threshold values on estimated XC(50)s was performed to ensure that the variability introduced by the serial dilution step is within acceptable overall variability limits. PMID:19675311

Popa-Burke, Ioana; Lupotsky, Brian; Boyer, Joseph; Gannon, William; Hughes, Rob; Kadwill, Paul; Lyerly, Donald; Nichols, Jason; Nixon, Elizabeth; Rimmer, Darren; Saiz-Nicolas, Isabel; Sanfiz-Pinto, Beatriz; Holland, Sue

2009-09-01

9

Research and Teaching: Implementing Inquiry-Based Learning in Teaching Serial Dilutions  

NSDL National Science Digital Library

The 5E model of inquiry-based learning was incorporated into a sophomore-level microbiology laboratory to increase student understanding of serial dilutions, a concept that is often difficult for most students to comprehend. Quantitative and qualitative assessments were conducted during the semester to determine the value of this approach for students; it was most beneficial to the middle 50% of the class.

Ann M. Stevens

2008-07-01

10

Transmission Probabilities of Mouse Parvovirus 1 to Sentinel Mice Chronically Exposed to Serial Dilutions of Contaminated Bedding  

PubMed Central

Intermittent serodetection of mouse parvovirus (MPV) infections in animal facilities occurs frequently when soiled bedding sentinel mouse monitoring systems are used. We evaluated induction of seroconversion in naïve single-caged weanling ICR mice (n = 10 per group) maintained on 5-fold serially diluted contaminated bedding obtained from SCID mice persistently shedding MPV1e. Soiled bedding from the infected SCID mice was collected, diluted, and redistributed weekly to cages housing ICR mice to represent chronic exposure to MPV at varying prevalence in a research colony. Sera was collected every other week for 12 wk and evaluated for reactivity to MPV nonstructural and capsid antigens by multiplex fluorescent immunoassay. Mice were euthanized after seroconversion, and DNA extracted from lymph node and spleen was evaluated by quantitative PCR. Cumulative incidence of MPV infection for each of the 7 soiled bedding dilution groups (range, 1:5 to 1:78125 [v/v]) was 100%, 100%, 90%, 20%, 70%, 60%, and 20%, respectively. Most seropositive mice (78%) converted within the first 2 to 3 wk of soiled bedding exposure, correlating to viral exposure when mice were 4 to 7 wk of age. Viral DNA was detected in lymphoid tissues collected from all mice that were seropositive to VP2 capsid antigen, whereas viral DNA was not detected in lymphoid tissue of seronegative mice. These data indicate seroconversion occurs consistently in young mice exposed to high doses of virus equivalent to fecal MPV loads observed in acutely infected mice, whereas seroconversion is inconsistent in mice chronically exposed to lower doses of virus. PMID:18524171

Besselsen, David G; Myers, Erin L; Franklin, Craig L; Korte, Scott W; Wagner, April M; Henderson, Kenneth S; Weigler, Benjamin J

2008-01-01

11

Differences in Median Ultraviolet Light Transmissions of Serial Homeopathic Dilutions of Copper Sulfate, Hypericum perforatum, and Sulfur  

PubMed Central

Homeopathic remedies are produced by potentising, that is, the serial logarithmic dilution and succussion of a mother tincture. Techniques like ultraviolet spectroscopy, nuclear magnetic resonance, calorimetry, or thermoluminescence have been used to investigate their physical properties. In this study, homeopathic centesimal (c) potencies (6c to 30c) of copper sulfate, Hypericum perforatum, and sulfur as well as succussed water controls were prepared. Samples of these preparations were exposed to external physical factors like heat, pressure, ultraviolet radiation, or electromagnetic fields to mimic possible everyday storage conditions. The median transmissions from 190?nm to 340?nm and 220?nm to 340?nm were determined by ultraviolet light spectroscopy on five measurement days distributed over several months. Transmissions of controls and potencies of sulfur differed significantly on two of five measurement days and after exposure to physical factors. Transmissions of potencies exposed to ultraviolet light and unexposed potencies of copper sulfate and Hypericum perforatum differed significantly. Potency levels 6c to 30c were also compared, and wavelike patterns of higher and lower transmissions were found. The Kruskal-Wallis test yielded significant differences for the potency levels of all three substances. Aiming at understanding the physical properties of homeopathic preparations, this study confirmed and expanded the findings of previous studies. PMID:23401712

Klein, Sabine D.; Sandig, Annegret; Baumgartner, Stephan; Wolf, Ursula

2013-01-01

12

Differences in Median Ultraviolet Light Transmissions of Serial Homeopathic Dilutions of Copper Sulfate, Hypericum perforatum, and Sulfur.  

PubMed

Homeopathic remedies are produced by potentising, that is, the serial logarithmic dilution and succussion of a mother tincture. Techniques like ultraviolet spectroscopy, nuclear magnetic resonance, calorimetry, or thermoluminescence have been used to investigate their physical properties. In this study, homeopathic centesimal (c) potencies (6c to 30c) of copper sulfate, Hypericum perforatum, and sulfur as well as succussed water controls were prepared. Samples of these preparations were exposed to external physical factors like heat, pressure, ultraviolet radiation, or electromagnetic fields to mimic possible everyday storage conditions. The median transmissions from 190?nm to 340?nm and 220?nm to 340?nm were determined by ultraviolet light spectroscopy on five measurement days distributed over several months. Transmissions of controls and potencies of sulfur differed significantly on two of five measurement days and after exposure to physical factors. Transmissions of potencies exposed to ultraviolet light and unexposed potencies of copper sulfate and Hypericum perforatum differed significantly. Potency levels 6c to 30c were also compared, and wavelike patterns of higher and lower transmissions were found. The Kruskal-Wallis test yielded significant differences for the potency levels of all three substances. Aiming at understanding the physical properties of homeopathic preparations, this study confirmed and expanded the findings of previous studies. PMID:23401712

Klein, Sabine D; Sandig, Annegret; Baumgartner, Stephan; Wolf, Ursula

2013-01-01

13

Generation of arbitrary monotonic concentration profiles by a serial dilution microfluidic network composed of microchannels with a high fluidic-resistance ratio.  

PubMed

This paper reports a serial dilution microfluidic network composed of microchannels with a high fluidic-resistance ratio for generating linear concentration profiles as well as logarithmic concentration profiles spanning 3 and 6 orders of magnitude. The microfluidic networks were composed of thin fluidic-resistance microchannels with 160 to 730 microm(2) cross-sectional areas and thick diffusion-mixing microchannels with 3,600 to 17,000 microm(2) cross-sectional areas, and were fabricated from polydimethylsiloxane by multilayer photolithography and replica molding. We proposed a design algorithm of the microfluidic network for an arbitrary monotonic concentration profile by means of a hydrodynamic calculation. Because of the high fluidic-resistance ratio of the fluidic-resistance microchannels to the diffusion-mixing microchannels, appropriate geometry and dimensions of the fluidic-resistance microchannels allowed us to obtain desired concentration profiles. The fabricated microfluidic network was compact, occupying a 8 x 18 to 21.0 x 13.5 mm(2) area on the microchip. Both the linear and the logarithmic concentration profiles were successfully generated with the error less than 15% for the linear concentration profile, 22% and 35% for the logarithmic concentration profiles of 3 and 6 orders of magnitude, respectively. The generated linear concentration profiles of the small molecule, calcein, were independent of the flow rate within the range of 0.009 to 0.23 microL/min. The concentration profiles of the large molecules, dextrans, depended on the flow rate and molecular weight. The required residence time of large molecules in the diffusion-mixing microchannel was correlated with dimensionless diffusion time, Fick number, and was discussed based on the scaling law. These compact, stable serial dilution microfluidic networks are expected to be applied to various integrated on-chip analyses. PMID:19495461

Hattori, Koji; Sugiura, Shinji; Kanamori, Toshiyuki

2009-06-21

14

Sex is always well worth its two-fold cost  

E-print Network

Sex is considered as an evolutionary paradox, since its evolutionary advantage does not necessarily overcome the two fold cost of sharing half of one's offspring's genome with another member of the population. Here we demonstrate that sexual reproduction can be evolutionary stable even when its Darwinian fitness is twice as low when compared to the fitness of asexual mutants. We also show that more than two sexes are always evolutionary unstable. Our approach generalizes the evolutionary game theory to analyze species whose members are able to sense the sexual state of their conspecifics and to switch sexes consequently. The widespread emergence and maintenance of sex follows therefore from its co-evolution with even more widespread environmental sensing abilities.

Feigel, Alexander; Engel, Assaf

2008-01-01

15

Serial Killers  

Microsoft Academic Search

We chose to research and study the effects of nature and nurture on serial killers. In our paper we used numerous examples of serial killers, such as Jeffrey Dahmer and John Wayne Gacy, to add credibility to our research. We researched their childhoods extensively and found ideas that prove both the nature and nurture side of the argument. We found

BrookeAlba; NatalieWittter; LizabethKaeb; AlisonNovakow

2012-01-01

16

Serial Wars  

ERIC Educational Resources Information Center

In a year filled with drama and hyperbole, the serials marketplace churned toward a future whose shape is the subject of fierce debate. Forecasts from commercial publishers touting collapse and disaster seemed oddly out of sync with the profits they enjoyed--around 25 percent on average. Nevertheless, in a market where prices continued to rise and…

Van Orsdel, Lee C.; Born, Kathleen

2007-01-01

17

Sea Urchin Embryology: Simple Dilutions 2  

NSDL National Science Digital Library

SUMMARY: Building on what was learned in SIMPLE DILUTION, students will determine the best dilution strategy to solve a dilution problem. 1. Students are given an unknown dye solution and asked to determine its concentration by comparing it with standards they create. 2. Repeated "serial" dilutions will be necessary to determine accurate concentration readings. 3. Varying the color of the filters and the path length will aid in seeing lower concentrations.

PhD David Epel (Stanford U. Hopkins Marine Station)

2006-12-20

18

Two-Fold Pricing to Guarantee Individual Profits and Maximum Social Welfare in  

E-print Network

as the congestion prices. Each source which uses a link resource is charged with the link's congestion price. The transmission rates and the congestion prices are iteratively updated using the gradient projection method until1 Two-Fold Pricing to Guarantee Individual Profits and Maximum Social Welfare in Multi-hop Wireless

Mohsenian-Rad, Hamed

19

Two-fold Pricing to Guarantee Individual Profits and Maximum Social Welfare in Wireless Access Networks  

E-print Network

resources efficiently. In this paper, we propose a market-based model with two-fold pricing (TFP the global optimal network performance may not be always guaranteed in the incentive-based strategies a fair revenue sharing. In [7], Neely proposed an economic model for stochastic wireless ad-hoc networks

Mohsenian-Rad, Hamed

20

The two-fold singularity of nonsmooth flows: Leading order dynamics in n-dimensions  

NASA Astrophysics Data System (ADS)

A discontinuity in a system of ordinary differential equations can create a flow that slides along the discontinuity locus. Prior to sliding, the flow may have collapsed onto the discontinuity, making the reverse flow non-unique, as happens when dry-friction causes objects to stick. Alternatively, a flow may slide along the discontinuity before escaping it at some indeterminable time, implying non-uniqueness in forward time. At a two-fold singularity these two behaviours are brought together, so that a single point may have multiple possible futures as well as histories. Two-folds are a generic consequence of discontinuities in three or more dimensions, and play an important role in both local and global dynamics. Despite this, until now nothing was known about two-fold singularities in systems of more than 3 dimensions. Here, the normal form of the two-fold is extended to higher dimensions, where we show that much of its lower dimensional dynamics survives.

Colombo, Alessandro; Jeffrey, Mike R.

2013-11-01

21

Star Formation in One and Two-Fold Resonance Ring Galaxies  

NASA Astrophysics Data System (ADS)

Resonance rings of star formation are a common phenomenon of early type barred spiral galaxies. Rings form by gas cloud gravitational coelesence near resonances with a turning perturbation. The resulting bright stars trace out the rings. We show how to use the Byrd et al. (1998) analytic formulation to model two-fold resonance rings with an example, NGC 3081. We obtain bar strength, orientation, and pattern speed reproducing the observed shapes and radial velocities. We show that an additional type, a one-fold resonance ring, can be produced by lop-sided perturbations. We identify shape, star formation, and velocity signatures of one-fold versus two-fold rings. As an example, we model the one-fold ring of NGC 4622. We study star formation in rings in more detail. Age of associations can be predicted as a function of angle around the ring. Correlating with observed colors or other age indicators permits empirical calibration of the indicator to study star formation and the ages of stellar complexes in other galaxies. Acknowledgements: T. Freeman and G. Byrd were supported by NSF grant 9802918. D. Ousley was supported by a Univerisyt of Alabama Mc Wane Undergraduate Research Fellowship. We thank R. But and G. Purcell for observational data on NGC 3081.

Freeman, T.; Byrd, G.; Ousley, D.; Domingue, D.

2000-05-01

22

The serial killer industry  

Microsoft Academic Search

Serial sex killing is developing into the moral panic of the 1990s but unlike previous moral panics about sex crime the activity of serial killing in Britain is very limited and the current concern is probably overstated. American definitions of the problem are becoming too influential and we are moving towards socially constructing a world-wide epidemic of serial killers. A

Keith Soothill

1993-01-01

23

Modern serial killers  

Microsoft Academic Search

The study of serial killing has been dominated by an individualized focus on the aetiology and biography of particular offenders. As such, it has tended to downplay the broader social, historical and cultural context of such acts. This article addresses this lacuna by arguing that serial killers are distinctively modern. It highlights six modern phenomena related to serial killing: (a)

Kevin D. Haggerty

2009-01-01

24

EBSCO's Serials Directory  

Microsoft Academic Search

Librarians may choose from print, online and CDROM formats when purchasing EBSCO's Serials Directory. Subject. access to serials titles and extensive bibliographic descriptions give the print and CD-ROM formats particular value as reference tools. Bibliographic authority, currency, access points and user aids for all three formats meet high standards. While each format has unique advantages depending on a library's size,

Jaclyn Walters

1989-01-01

25

High speed serial interface Why serial interface?  

E-print Network

Interface(SGMII) : Total 8 lines for 1.25 Gb/s · Research area Serial interface building block design ­ PLL, Temperature (PVT) robust PLL ­ Low noise PLL with supply noise insensitive VCO ­ A PLL with fast Controller Current Controller Supply noise informationVdd Vdd Supply noise insensitive VCO Continuous

Choi, Woo-Young

26

HIPPI/Serial-HIPPI  

SciTech Connect

The High-Performance Parallel Interface (HIPPI) is a simple high-performance, point-to-point channel for transmitting digital data at peak data rates of 800 or 1600 Mbit/S. The transmission distance between data processing equipment using copper cabling can be up to 25 meters. This distance may be increased by using a Serial-HIPPI extender. This paper describes the HIPPI channel, the choices considered for a serial extender, and the resulting agreement for the Serial-HIPPI specification. 5 refs., 4 figs.

Tolmie, D.E. (Los Alamos National Lab., NM (United States)); Halvorson, M.G. (Digital Equipment Corp., Los Alamos, NM (United States))

1991-01-01

27

An unusual two-fold interpenetrating polyrotaxane motif comprised of two interlocked sets of identical diamond nets  

NASA Astrophysics Data System (ADS)

A novel 3D coordination polymer [Cd2(cca)2(bib)3]?3H2O (1, H2cca = 4-carboxycinnamic acid, bib = 1,4-bis(imidazole)butane) has been synthesized. This compound exhibits an unusual two-fold interpenetrating polyrotaxane-like structure comprised of two interlocked sets of identical diamond nets.

Guo, Hua-dong; Fu, Zi-ao; Guo, Xian-min; Li, Xin-long; Chen, Rui-zhan; Qi, Yan-juan; Zou, Heng-ye

2013-04-01

28

Classifying serial killers  

Microsoft Academic Search

We attempted to match the appearance and demeanor of 27 serial killers to the postmortem ‘signatures’ found on their victims’ bodies. Our results suggest that a link may exist between postmortem signatures and two complementary appearance–demeanor types.

Donald I Promish; David Lester

1999-01-01

29

Serial Verbs in Ibibio  

E-print Network

Kansas Working Papers in Linguistics, Vol. 35 (2014), 129-148 129 Serial Verbs in Ibibio Travis Major University of Kansas 1. Introduction This paper investigates serial verb constructions (SVC) in Ibibio, a Niger-Congo language spoken... syntactic and semantic grounds and also to fit Ibibio in with the typological literature on SVCs. 2. Ibibio background Ibibio is a Lower Cross language of the East Benue-Congo branch in the Niger-Congo language phylum, which is spoken in the southern part...

Major, Travis

2015-03-04

30

The Serial Perplex.  

ERIC Educational Resources Information Center

The problems associated with the acquisition of periodicals from various sources and different systems used by two University of Alabama libraries for the acquisition, controlling, and recording of serials are described in this report. Sources identified and discussed include local sources and suppliers, direct subscriptions placed with…

Blackwell, Maree Macon; Chopra, Pearl

31

Serial interface controller  

SciTech Connect

The idea of building a Serial Interface Controller (SIC) proposed by Paul O`Connor, Instrumentation Division, BNL is to determine the feasibility of incorporating a Serial Interface Controlled CMOS IC`s for charge amplification, shaping, analog storage and multiplexing used in particle detectors for high energy physics experiments. The serial data pumped into the CMOS ICs will be used to control many circuit parameters like digitally controlled gain, shaping time, precision preamplifier calibration circuits and many other parameters like timing discriminators mode of operation. The SIC board built will be tested on a Serial Interface Controlled Digital - to - Analog Convertor, which follows either Motorola`s SPI/QSPI or National Semiconductors Microwire interface technique. The DAC chosen for this was MAXIM`s MAX537, a Quad, 12-bit DAC. The function of this controller can be achieved by using some on-shelf micro-controllers like the Motorola`s MC68HC11, which offers dedicated SPI ports. The drawback encountered in using this controller is the overhead involved in putting together an user interface where the user can dynamically change its settings and load the SIC device. This is very critical in testing fewer number of CMOS IC`s having SIC. The SIC board described here takes care of this dynamic user interface issue.

Kandasamy, A.

1995-04-14

32

Classifying serial killers.  

PubMed

We attempted to match the appearance and demeanor of 27 serial killers to the postmortem 'signatures' found on their victims' bodies. Our results suggest that a link may exist between postmortem signatures and two complementary appearance-demeanor types. PMID:10643649

Promish, D I; Lester, D

1999-11-01

33

Suicide in serial killers.  

PubMed

In a sample of 248 killers of two victims in America from 1900 to 2005, obtained from an encyclopedia of serial killers by Newton (2006), those completing suicide did not differ in sex, race, or the motive for the killing from those who were arrested. PMID:20402450

Lester, David; White, John

2010-02-01

34

Transmission coefficient and two-fold degenerate discrete spectrum of spin-1 bosons in a double-step potential  

E-print Network

The scattering of spin-1 bosons in a nonminimal vector double-step potential is described in terms of eigenstates of the helicity operator and it is shown that the transmission coefficient is insensitive to the choice of the polarization of the incident beam. Poles of the transmission amplitude reveal the existence of a two-fold degenerate spectrum. The results are interpreted in terms of solutions of two coupled effective Schr\\"{o}dinger equations for a finite square well with additional $\\delta $-functions situated at the borders.

de Oliveira, L P

2015-01-01

35

Transmission coefficient and two-fold degenerate discrete spectrum of spin-1 bosons in a double-step potential  

E-print Network

The scattering of spin-1 bosons in a nonminimal vector double-step potential is described in terms of eigenstates of the helicity operator and it is shown that the transmission coefficient is insensitive to the choice of the polarization of the incident beam. Poles of the transmission amplitude reveal the existence of a two-fold degenerate spectrum. The results are interpreted in terms of solutions of two coupled effective Schr\\"{o}dinger equations for a finite square well with additional $\\delta $-functions situated at the borders.

L. P. de Oliveira; A. S. de Castro

2015-04-01

36

HIPPI\\/Serial-HIPPI  

Microsoft Academic Search

The High-Performance Parallel Interface (HIPPI) is a simple high-performance, point-to-point channel for transmitting digital data at peak data rates of 800 or 1600 Mb\\/s. The transmission distance between data processing equipment using copper cabling can be up to 25 m. This distance may be increased by using a Serial-HIPPI extender. The authors describe the HIPPI channel, the choices considered for

D. E. Tolmie; M. G. Halvorson

1992-01-01

37

Delaware's first serial killer.  

PubMed

The violent murder of Shirley Ellis on November 29, 1987, marked the beginning of the strange and terrible tale of Steven Bryan Pennell's reign as the state of Delaware's first convicted serial killer. Three more bodies followed the first victim, and all had been brutally beaten and sadistically tortured. The body of a fifth woman has never been found. State and county police collaborated with the FBI to identify and hunt down their suspect, forming a task force of over 100 officers and spending about one million dollars. Through their knowledge and experience with other serial killers, the FBI was able to make an amazingly accurate psychological profile of Delaware's serial killer. After months of around-the-clock surveillance, Steven Pennell was arrested on November 29, 1988, one year to the day after the first victim was found. Pennell was found guilty in the deaths of the first two victims on November 29, 1989, and plead no contest to the murder of two others on October 30, 1991. Still maintaining his innocence, he asked for the death penalty so that he could spare his family further agony. Steven Pennell was executed by lethal injection on March 15, 1992. PMID:11125664

Inguito, G B; Sekula-Perlman, A; Lynch, M J; Callery, R T

2000-11-01

38

Serial Position Learning in Honeybees  

Microsoft Academic Search

Learning of stimulus sequences is considered as a characteristic feature of episodic memory since it contains not only a particular item but also the experience of preceding and following events. In sensorimotor tasks resembling navigational performance, the serial order of objects is intimately connected with spatial order. Mammals and birds develop episodic(-like) memory in serial spatio-temporal tasks, and the honeybee

Randolf Menzel; Thomas Burne

2009-01-01

39

Serials Cancellation Project. Final Report.  

ERIC Educational Resources Information Center

A serials cancellation pilot project was conducted by the Pittsburgh Regional Library Center (PRLC) from August 1981 to December 1983 in order to demonstrate the utility of using a large online union list of serials for making and reporting collection management decisions. A total of 21 academic libraries and one public library from Pennsylvania,…

Carter, Ruth C.; Bruntjen, Scott

40

A bit serial sequential circuit  

NASA Technical Reports Server (NTRS)

Normally a sequential circuit with n state variables consists of n unique hardware realizations, one for each state variable. All variables are processed in parallel. This paper introduces a new sequential circuit architecture that allows the state variables to be realized in a serial manner using only one next state logic circuit. The action of processing the state variables in a serial manner has never been addressed before. This paper presents a general design procedure for circuit construction and initialization. Utilizing pass transistors to form the combinational next state forming logic in synchronous sequential machines, a bit serial state machine can be realized with a single NMOS pass transistor network connected to shift registers. The bit serial state machine occupies less area than other realizations which perform parallel operations. Moreover, the logical circuit of the bit serial state machine can be modified by simply changing the circuit input matrix to develop an adaptive state machine.

Hu, S.; Whitaker, S.

1990-01-01

41

Two-fold odd-even effect in self-assembled nanowires from oligopeptide-polymer-substituted perylene bisimides.  

PubMed

Organic nanowires are important building blocks for nanoscopic organic electronic devices. In order to ensure efficient charge transport through such nanowires, it is important to understand in detail the molecular parameters that guide self-assembly of ?-conjugated molecules into one-dimensional stacks with optimal constructive ?-? overlap. Here, we investigated the subtle relationship between molecular structure and supramolecular arrangement of the chromophores in self-assembled nanowires prepared from perylene bisimides with oligopeptide-polymer side chains. We observed a "two-fold" odd-even effect in circular dichroism spectra of these derivatives, depending on both the number of l-alanine units in the oligopeptide segments and length of the alkylene spacer between chromophore and oligopeptide substituents. Our results indicate that there is a complex interplay between the translation of molecular chirality into supramolecular helicity and the molecules' inherent propensity for well-defined one-dimensional aggregation into ?-sheet-like superstructures in the presence of a central chromophore. Strong excitonic coupling as expressed by the appearance of hypsochromically and bathochromically shifted UV-vis absorptions and strong CD signals was systematically observed for molecules with an odd number of l-alanines in the side chains. The latter derivatives gave rise to nanowires with a significantly higher electron mobility. Our results, hence, provide an important design rule for self-assembled organic nanowires. PMID:24524326

Marty, Roman; Nigon, Robin; Leite, Deborah; Frauenrath, Holger

2014-03-12

42

Serial Checkin Procedure .1. 4 December 2013 Serial Checkin: procedure  

E-print Network

(International Standard Serial Number, e.g. 1234-5678 or 1234-567x), title or word search. · Check title hasn receive directly from the publisher may contain a renewal invoice). · Search for the title using ISSN

43

Debugging Serial and Parallel Codes  

NSDL National Science Digital Library

Introduction to debugger software. Serial debugging of array indexing, arguments mismatch, infinite loops, pointer misuse, and memory allocation. Parallel debugging of process count, shared memory, MPI I/O, collective communications, and OpenMP scope.

NCSA

44

Serial Item Contribution Identifier: New SISAC Code.  

ERIC Educational Resources Information Center

Discusses the benefits of the Serial Item Contribution Identifier (SICI) standard for serials handling. Developed by the Serials Industry Systems Advisory Committee (SISAC), SICI applications through the use of a SISAC barcode are expected to benefit shipping, ordering, serials processing and claiming, document delivery, and information exchange.…

Computers in Libraries, 1993

1993-01-01

45

Serials Budget Management Using a Microcomputer  

Microsoft Academic Search

This paper describes a database application designed and programmed in dBase III + for management of serials subscriptions and serials budgeting at a small academic library. Use of a database manager enables the allocation of serials subscription costs to academic departments, and allows library managers to track changes in the serials budget, to assign additional funds to the book budget

Lynne Myers Hayman

1991-01-01

46

Serial Input Output  

SciTech Connect

Serial Input/Output (SIO) is designed to be a long term storage format of a sophistication somewhere between simple ASCII files and the techniques provided by inter alia Objectivity and Root. The former tend to be low density, information lossy (floating point numbers lose precision) and inflexible. The latter require abstract descriptions of the data with all that that implies in terms of extra complexity. The basic building blocks of SIO are streams, records and blocks. Streams provide the connections between the program and files. The user can define an arbitrary list of streams as required. A given stream must be opened for either reading or writing. SIO does not support read/write streams. If a stream is closed during the execution of a program, it can be reopened in either read or write mode to the same or a different file. Records represent a coherent grouping of data. Records consist of a collection of blocks (see next paragraph). The user can define a variety of records (headers, events, error logs, etc.) and request that any of them be written to any stream. When SIO reads a file, it first decodes the record name and if that record has been defined and unpacking has been requested for it, SIO proceeds to unpack the blocks. Blocks are user provided objects which do the real work of reading/writing the data. The user is responsible for writing the code for these blocks and for identifying these blocks to SIO at run time. To write a collection of blocks, the user must first connect them to a record. The record can then be written to a stream as described above. Note that the same block can be connected to many different records. When SIO reads a record, it scans through the blocks written and calls the corresponding block object (if it has been defined) to decode it. Undefined blocks are skipped. Each of these categories (streams, records and blocks) have some characteristics in common. Every stream, record and block has a name with the condition that each stream, record or block name must be unique in its category (i.e. all streams must have different names, but a stream can have the same name as a record). Each category is an arbitrary length list which is handled by a 'manager' and there is one manager for each category.

Waite, Anthony; /SLAC

2011-09-07

47

The mathematics of dilution.  

PubMed

The major objection to homeopathic medicine is that the doses of medicine prescribed in some cases are too dilute for any active ingredient to be present. The medicines would hence be rendered inactive, necessitating novel explanations for the action. A further examination of dilution in the light of the Langmuir equation shows that homeopathic medicines may not be as dilute as a simplistic application of Avogadro's Principle suggests, due to surface effects. PMID:24685420

Chatterjee, Barun Kumar

2014-04-01

48

Implementing a Serials Barcoding Project.  

ERIC Educational Resources Information Center

Discusses the process of planning and implementing a barcode project for library serials based on experiences at the University of Arkansas Fayetteville library. Topics include dumb versus smart barcodes, cataloging, classification, application rate of barcode labels, and library staff participation. (Author/LRW)

Lennertz, Lora L.; Conway, Cheryl L.

1997-01-01

49

International Standard Serial Number (ISSN)  

E-print Network

International Standard Serial Number (ISSN) Presented by: Marcia Salmon Graduate Journal world-wide #12;ISSN Portal The ISSN register may be accessed through the ISSN Portal (http://portal://www.collectionscanada.gc.ca/isn/ 041011-2000-e.html ISSN Portal http://portal.issn.org #12;

50

Serials Control Systems on Microcomputers.  

ERIC Educational Resources Information Center

This paper describes seven commercially available microcomputer serials systems in terms of the following functions: cataloging/title entry, searching, check-in, claims, routing, bindery control, duplicates control, financial control, ordering, subscription renewal/payment, vendor records, reports, technical descriptions, costs, and number of…

Leatherbury, Maurice C.

1984-01-01

51

Serials Control System Procedures and Policies.  

ERIC Educational Resources Information Center

This document includes procedures and policies for a networked serials control system originally developed at the Grainger Engineering Library Information Center at the University of Illinois at Urbana-Champaign (UIUC). The serials control systems encompass serials processing, public service, and end-user functions. The system employs a…

Schlembach, Mary C.

52

The Social Construction of a Serial Killer  

Microsoft Academic Search

Much psychological research examining the serial killer has adopted an essentialist theoretical focus concentrating on the `nature' of the individual who commits the murder. This study, in contrast, aims to analyse the talk of a serial killer using principles taken from discursive psychology. A courtroom transcript concerning the confession to 10 murders by the serial killer, Dennis Rader, was analysed.

Ross Bartels; Ceri Parsons

2009-01-01

53

SERIAL KILLER COMMUNIQUÉS: HELPFUL OR HURTFUL  

Microsoft Academic Search

For centuries serial killers have plagued society. These social deviants cunningly meander through communities murdering the most vulnerable: women, children, the homeless, and the elderly. Often, the serial killers avoid capture because they are highly mobile, tend to leave little evidence, and keep their thoughts and deeds to themselves. Occasionally, serial killers communicate with police or the mass media. It

Tomas Guillen

54

Riddles in serial murder: A synthesis  

Microsoft Academic Search

This article blends the conclusions of four former law enforcement personnel who have investigated and apprehended serial killers, with pertinent principles derived primarily from the field of psychoanalysis. The four—John Douglas, Roy Hazelwood, Robert Keppel, and Robert Ressler—have written extensively about their investigations of serial killers. In their writings, they have answered many questions about the personality development of serial

Terry A Whitman; Donald Akutagawa

2004-01-01

55

Toward a National Serials Data Program: Final Report of the National Serials Pilot Project.  

ERIC Educational Resources Information Center

The National Serials Pilot Project, Phase II of the National Serials Data Program, is described. Utilizing the MARC format for processing serials, the objectives were: (1) to create a machine-readable file containing live serials in the fields of science and technology, (2) to produce a number of preliminary listings, and (3) to produce one or…

Johnson, Donald W.

56

Serial Killers with Military Experience: Applying Learning Theory to Serial Murder  

Microsoft Academic Search

Scholars have endeavored to study the motivation and causality behind serial murder by researching biological, psychological, and sociological variables. Some of these studies have provided support for the relationship between these variables and serial murder. However, the study of serial murder continues to be an exploratory rather than explanatory research topic. This article examines the possible link between serial killers

Tammy Castle; Christopher Hensley

2002-01-01

57

Serial dependence in visual perception  

PubMed Central

Visual input often arrives in a noisy and discontinuous stream, owing to head and eye movements, occlusion, lighting changes, and many other factors. Yet the physical world is generally stable—objects and physical characteristics rarely change spontaneously. How then does the human visual system capitalize on continuity in the physical environment over time? Here we show that visual perception is serially dependent, using both prior and present input to inform perception at the present moment. Using an orientation judgment task, we found that even when visual input changes randomly over time, perceived orientation is strongly and systematically biased toward recently seen stimuli. Further, the strength of this bias is modulated by attention and tuned to the spatial and temporal proximity of successive stimuli. These results reveal a serial dependence in perception characterized by a spatiotemporally tuned, orientation-selective operator—which we call a continuity field—that may promote visual stability over time. PMID:24686785

Fischer, Jason; Whitney, David

2014-01-01

58

A two-fold interpenetrating 3D metal-organic framework material constructed from helical chains linked via 4,4'-H{sub 2}bpz fragments  

SciTech Connect

A 3-connected dia-f-type metal-organic framework compound {l_brace}[Ag(L){sub 3/2}H{sub 2}PO{sub 4}]{r_brace}{sub n} (1) has been synthesized by self-assembly of 4,4'-H{sub 2}bpz (L=4,4'-H{sub 2}bpz=3,3',5,5'-tetramethyl-4,4'-bipyrazole) and Ag{sub 4}P{sub 2}O{sub 7} under hydrothermal conditions. It crystallizes in the tetragonal space group I4{sub 1}/acd with a=21.406(4) A, b=21.406(4) A, c=36.298(8) A, Z=32. X-ray single-crystal diffraction reveals that 1 has a three-dimensional framework with an unprecedented alternate left- and right-handed helices structure, featuring a non-uniform two-fold interpenetrated (4.14{sup 2}) net. Photoluminescent investigation reveals that the title compound displays interesting emissions in a wide region, which shows that the title compound may be a good potential candidate as a photoelectric material. - Graphical abstract: A 3-connected dia-f-type metal-organic framework compound [Ag(4,4'-bpz){sub 3/2}H{sub 2}PO{sub 4}] shows unprecedented alternating left- and right-handed helices structure, featuring a non-uniform two-fold interpenetrated (4.14{sup 2}) net.

Xie Yiming [State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 35002 (China); College of Materials Science and Engineering, Huaqiao University, the Key Laboratory for Functional Materials of Fujian Higher Education, Quanzhou, Fujian 362021 (China); Zhao Zhenguo; Wu Xiaoyuan; Zhang Qisheng; Chen Lijuan; Wang Fei; Chen Shanci [State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 35002 (China); Lu Canzhong [State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 35002 (China)], E-mail: czlu@fjirsm.ac.cn

2008-12-15

59

Serial murder by healthcare professionals.  

PubMed

The prosecution of Charles Cullen, a nurse who killed at least 40 patients over a 16-year period, highlights the need to better understand the phenomenon of serial murder by healthcare professionals. The authors conducted a LexisNexis search which yielded 90 criminal prosecutions of healthcare providers that met inclusion criteria for serial murder of patients. In addition we reviewed epidemiologic studies, toxicology evidence, and court transcripts, to provide data on healthcare professionals who have been prosecuted between 1970 and 2006. Fifty-four of the 90 have been convicted; 45 for serial murder, four for attempted murder, and five pled guilty to lesser charges. Twenty-four more have been indicted and are either awaiting trial or the outcome has not been published. The other 12 prosecutions had a variety of legal outcomes. Injection was the main method used by healthcare killers followed by suffocation, poisoning, and tampering with equipment. Prosecutions were reported from 20 countries with 40% taking place in the United States. Nursing personnel comprised 86% of the healthcare providers prosecuted; physicians 12%, and 2% were allied health professionals. The number of patient deaths that resulted in a murder conviction is 317 and the number of suspicious patient deaths attributed to the 54 convicted caregivers is 2113. These numbers are disturbing and demand that systemic changes in tracking adverse patient incidents associated with presence of a specific healthcare provider be implemented. Hiring practices must shift away from preventing wrongful discharge or denial of employment lawsuits to protecting patients from employees who kill. PMID:18409454

Yorker, Beatrice Crofts; Kizer, Kenneth W; Lampe, Paula; Forrest, A R W; Lannan, Jacquetta M; Russell, Donna A

2008-01-01

60

Serial murder by healthcare professionals.  

PubMed

The prosecution of Charles Cullen, a nurse who killed at least 40 patients over a 16-year period, highlights the need to better understand the phenomenon of serial murder by healthcare professionals. The authors conducted a LexisNexis search which yielded 90 criminal prosecutions of healthcare providers that met inclusion criteria for serial murder of patients. In addition we reviewed epidemiologic studies, toxicology evidence, and court transcripts, to provide data on healthcare professionals who have been prosecuted between 1970 and 2006. Fifty-four of the 90 have been convicted; 45 for serial murder, four for attempted murder, and five pled guilty to lesser charges. Twenty-four more have been indicted and are either awaiting trial or the outcome has not been published. The other 12 prosecutions had a variety of legal outcomes. Injection was the main method used by healthcare killers followed by suffocation, poisoning, and tampering with equipment. Prosecutions were reported from 20 countries with 40% taking place in the United States. Nursing personnel comprised 86% of the healthcare providers prosecuted; physicians 12%, and 2% were allied health professionals. The number of patient deaths that resulted in a murder conviction is 317 and the number of suspicious patient deaths attributed to the 54 convicted caregivers is 2113. These numbers are disturbing and demand that systemic changes in tracking adverse patient incidents associated with presence of a specific healthcare provider be implemented. Hiring practices must shift away from preventing wrongful discharge or denial of employment lawsuits to protecting patients from employees who kill. PMID:17199622

Yorker, Beatrice Crofts; Kizer, Kenneth W; Lampe, Paula; Forrest, A R W; Lannan, Jacquetta M; Russell, Donna A

2006-11-01

61

Reconciling rising serials costs, the serials budget, and reference needs in a medical library serials retrenchment program: a methodology.  

PubMed

Devising a coherent serials retrenchment plan while maintaining quality reference service is a dilemma faced by increasing numbers of medical librarians. In 1991, the staff of the Shiffman Medical Library, Wayne State University, began to address increasing serials budget reductions that by 1994 amounted to a projected 20% maximum cut. The resulting retrenchment plan combined an ongoing serials use study, faculty and librarian reviews of cancellation lists, and systematic refinements in interlibrary cooperation and document delivery service. The Shiffman plan provides a constructive framework that can be adapted to other medical libraries facing immediate, major serials retrenchment. PMID:10142675

Spang, L

1995-01-01

62

Stabilization of a prion strain of synthetic origin requires multiple serial passages.  

PubMed

Transmission of prions to a new host is frequently accompanied by strain adaptation, a phenomenon that involves reduction of the incubation period, a change in neuropathological features and, sometimes, tissue tropism. Here we show that a strain of synthetic origin (SSLOW), although serially transmitted within the same species, displayed the key attributes of the strain adaptation process. At least four serial passages were required to stabilize the strain-specific SSLOW phenotype. The biological titration of SSLOW revealed a correlation between clinical signs and accumulation of PrP(Sc) in brains of animals inoculated with high doses (10(-1)-10(-5) diluted brain material), but dissociation between the two processes at low dose inocula (10(-6)-10(-8) diluted brain material). At low doses, several asymptomatic animals harbored large amounts of PrP(Sc) comparable with those seen in the brains of terminally ill animals, whereas one clinically ill animal had very little, if any, PrP(Sc). In summary, the current study illustrates that the phenomenon of prion strain adaptation is more common than generally thought and could be observed upon serial transmission without changing the host species. When PrP(Sc) is seeded by recombinant PrP structures different from that of authentic PrP(Sc), PrP(Sc) properties continued to evolve for as long as four serial passages. PMID:22807452

Makarava, Natallia; Kovacs, Gabor G; Savtchenko, Regina; Alexeeva, Irina; Budka, Herbert; Rohwer, Robert G; Baskakov, Ilia V

2012-08-31

63

Dilution, Concentration, and Flotation  

ERIC Educational Resources Information Center

As both classroom teaching practice and literature show, many students have difficulties learning science concepts such as density. Here are some investigations that identify the relationship between density and floating through experimenting with successive dilution of a liquid, or the systematic change of concentration of a saltwater solution.…

Liang, Ling; Schmuckler, Joseph S.

2004-01-01

64

Helium dilution refrigeration system  

DOEpatents

A helium dilution refrigeration system operable over a limited time period, and recyclable for a next period of operation is disclosed. The refrigeration system is compact with a self-contained pumping system and heaters for operation of the system. A mixing chamber contains [sup 3]He and [sup 4]He liquids which are precooled by a coupled container containing [sup 3]He liquid, enabling the phase separation of a [sup 3]He rich liquid phase from a dilute [sup 3]He-[sup 4]He liquid phase which leads to the final stage of a dilution cooling process for obtaining low temperatures. The mixing chamber and a still are coupled by a fluid line and are maintained at substantially the same level with the still cross sectional area being smaller than that of the mixing chamber. This configuration provides maximum cooling power and efficiency by the cooling period ending when the [sup 3]He liquid is depleted from the mixing chamber with the mixing chamber nearly empty of liquid helium, thus avoiding unnecessary and inefficient cooling of a large amount of the dilute [sup 3]He-[sup 4]He liquid phase. 2 figs.

Roach, P.R.; Gray, K.E.

1988-09-13

65

Serial turbo trellis coded modulation using a serially concatenated coder  

NASA Technical Reports Server (NTRS)

Serial concatenated trellis coded modulation (SCTCM) includes an outer coder, an interleaver, a recursive inner coder and a mapping element. The outer coder receives data to be coded and produces outer coded data. The interleaver permutes the outer coded data to produce interleaved data. The recursive inner coder codes the interleaved data to produce inner coded data. The mapping element maps the inner coded data to a symbol. The recursive inner coder has a structure which facilitates iterative decoding of the symbols at a decoder system. The recursive inner coder and the mapping element are selected to maximize the effective free Euclidean distance of a trellis coded modulator formed from the recursive inner coder and the mapping element. The decoder system includes a demodulation unit, an inner SISO (soft-input soft-output) decoder, a deinterleaver, an outer SISO decoder, and an interleaver.

Divsalar, Dariush (Inventor); Dolinar, Samuel J. (Inventor); Pollara, Fabrizio (Inventor)

2010-01-01

66

Serial turbo trellis coded modulation using a serially concatenated coder  

NASA Technical Reports Server (NTRS)

Serial concatenated trellis coded modulation (SCTCM) includes an outer coder, an interleaver, a recursive inner coder and a mapping element. The outer coder receives data to be coded and produces outer coded data. The interleaver permutes the outer coded data to produce interleaved data. The recursive inner coder codes the interleaved data to produce inner coded data. The mapping element maps the inner coded data to a symbol. The recursive inner coder has a structure which facilitates iterative decoding of the symbols at a decoder system. The recursive inner coder and the mapping element are selected to maximize the effective free Euclidean distance of a trellis coded modulator formed from the recursive inner coder and the mapping element. The decoder system includes a demodulation unit, an inner SISO (soft-input soft-output) decoder, a deinterleaver, an outer SISO decoder, and an interleaver.

Divsalar, Dariush (Inventor); Dolinar, Samuel J. (Inventor); Pollara, Fabrizio (Inventor)

2011-01-01

67

Scientific and Technical Serials Holdings Optimization in an Inefficient Market: A LSU Serials Redesign Project Exercise.  

ERIC Educational Resources Information Center

Analyzes the structure of the library market for scientific and technical (ST) serials. Describes an exercise aimed at a theoretical reconstruction of the ST-serials holdings of Louisiana State University (LSU) Libraries. Discusses the set definitions, measures, and algorithms necessary in the design of a computer program to appraise ST serials

Bensman, Stephen J.; Wilder, Stanley J.

1998-01-01

68

XBS: A Streaming Binary Serializer for High Performance Computing  

Microsoft Academic Search

High performance distributed systems communication requires that data first be serialized into a byte sequence suitable for transmis- sion. A variety of different formats exist for serialization, ranging from XML-based formats to more efficient binary formats. This paper presents the XBS binary serialization library. XBS differs from other binary serializers in that it is a streaming serializer (as opposed to

Kenneth Chiu

2004-01-01

69

Is Accuracy Everything? A Study of Two Serials Directories  

Microsoft Academic Search

This study found that Ulrich's and Serials Directory offer a wide, and often disparate, amount of information about where serials are indexed or ed, with Ulrich's indexing more titles overall than Serials Directory, and more dead titles than the other directory. Serials Directory is the only provider that lists where EBSCO serials are indexed or ed. Both directories also provide

Marybeth Grimes; Sara E. Morris

2006-01-01

70

Examining Serial Sections of an Apple  

NSDL National Science Digital Library

In this activity, students make serial sections of an apple. Students make cross-section prints of the top portion of the apple, then another print further into the apple, and so on until they get to the bottom of the apple. This serial sectionin

John Eichinger

2009-05-15

71

Serial Cohabitation and the Marital Life Course  

ERIC Educational Resources Information Center

Using cohort data from the National Longitudinal Survey of Youth, this paper tracks the experiences of "serial cohabitors." Results indicate that only a minority of cohabiting women (about 15%-20%) were involved in multiple cohabitations. Serial cohabitations were overrepresented among economically disadvantaged groups, especially those with low…

Lichter, Daniel T.; Qian, Zhenchao

2008-01-01

72

Modus operandi of female serial killers.  

PubMed

The modus operandi of female serial killers was examined from a chronology of 58 cases in America and 47 cases in 17 other countries, compiled over 25-year intervals. Female serial killers in other countries accounted for a disproportionately greater number of victims, but those in America managed a longer killing career when associated with a low profile modus operandi. PMID:9621726

Wilson, W; Hilton, T

1998-04-01

73

The Serial Murderer's Motivations: An Interdisciplinary Review.  

ERIC Educational Resources Information Center

Defines serial killer as individual who murders two or more victims over an extended period of time, ranging from days to years, with the crimes often being sexually motivated. Reviews existing motivational theories of serial murder and proposes additional explications from range of disciplines. Presents suggestions for future research and…

DeHart, Dana D.; Mahoney, John M.

1994-01-01

74

Bus Serialization for Reducing Power Consumption  

Microsoft Academic Search

yyy Shared-bus chip multiprocessors require buses with long wires. The portion of power consumed in wires relatively increases with device scaling. In this paper, we advocate the use of bus serialization to reduce bus power consumption. Bus serialization decreases the number of wires, and increases the pitch between wires. The wider pitch decreases the coupling capacitances of wires, and consequently

Naoya Hatta; Niko Demus Barli; Chitaka Iwama; Luong Dinh Hung; Daisuke Tashiro; Shuichi Sakai; Hidehiko Tanaka

2006-01-01

75

Serial killers with military experience: applying learning theory to serial murder.  

PubMed

Scholars have endeavored to study the motivation and causality behind serial murder by researching biological, psychological, and sociological variables. Some of these studies have provided support for the relationship between these variables and serial murder. However, the study of serial murder continues to be an exploratory rather than explanatory research topic. This article examines the possible link between serial killers and military service. Citing previous research using social learning theory for the study of murder, this article explores how potential serial killers learn to reinforce violence, aggression, and murder in military boot camps. As with other variables considered in serial killer research, military experience alone cannot account for all cases of serial murder. Future research should continue to examine this possible link. PMID:12150084

Castle, Tammy; Hensley, Christopher

2002-08-01

76

Organization of Serials Work for Manual and Automated Systems.  

ERIC Educational Resources Information Center

Recommends the grouping together of serials functions, describes the application of such serials management in a university library, and appraises the expected organizational impact of automation on a centralized serials department. (FM)

Collver, Mitsuko

1980-01-01

77

He dilution refrigerator  

NASA Astrophysics Data System (ADS)

We describe the preparation of ultracold atomic clouds in a dilution refrigerator. The closed-cycle 3He/4He cryostat was custom made to provide optical access for laser cooling, optical manipulation and detection of atoms. We show that the cryostat meets the requirements for cold atom experiments, specifically in terms of operating a magneto-optical trap, magnetic traps and magnetic transport under ultrahigh vacuum conditions. The presented system is a step toward the creation of a quantum hybrid system combining ultracold atoms and solid-state quantum devices.

Jessen, F.; Knufinke, M.; Bell, S. C.; Vergien, P.; Hattermann, H.; Weiss, P.; Rudolph, M.; Reinschmidt, M.; Meyer, K.; Gaber, T.; Cano, D.; Günther, A.; Bernon, S.; Koelle, D.; Kleiner, R.; Fortágh, J.

2014-09-01

78

Anomalies in vortex lattice dynamics driven by induced ac currents in superconducting films with magnetic arrays of two-fold symmetry  

NASA Astrophysics Data System (ADS)

We study the dynamics of the vortex lattice driven by ac induced currents in the critical state regime, for T > 0.70 TC. The samples are superconducting films grown on top of two-fold symmetry array of magnetic dots. In these heterostructures, the induced ac currents flow parallel to the short and to the long side of the pinning array in different areas of the samples simultaneously. This behavior produces remarkable effects in the vortex lattice dynamics. First of all, periodic features are observed in the ac susceptibility versus applied magnetic field measurements which are related to matching effects between the vortex lattices and the magnetic array. However, the vortex lattice reconfiguration observed in magnetotransport experiments is absent. Some of these features are revealed as maxima instead of being minima, indicating higher mobility at certain matching fields. Competing unstable vortex configurations could lead to increase vortex mobility precluding the reconfiguration transition. At high temperatures, where the matching effects show up, the magnetic permeability of the dots is the mechanism that governs the JC(T) behavior. Moreover, the temperature dependence of the pinning force FP(T) shows a temperature crossover related to an unexpected enhancement in vortex mobility. Vortex–vortex interaction and the interplay between trapped and interstitial vortices are a hint to explain these phenomena.

Moreno, A. J.; Chiliotte, C. E.; Pasquini, G.; Bekeris, V.; Gomez, A.; del Valle, J.; Gonzalez, E. M.; Prieto, J. L.; Vicent, J. L.

2015-01-01

79

Evidence of a two-fold glacial advance during the last glacial maximum in the Tagliamento end moraine system (eastern Alps)  

NASA Astrophysics Data System (ADS)

The glacial history of the Tagliamento morainic amphitheater (southeastern Alpine foreland, Italy) during the last glacial maximum (LGM) has been reconstructed by means of a geological survey and drillings, radiocarbon dating and pollen analysis in the amphitheater and in the sandur. Two phases of glacial culmination, separated by a distinct recession, are responsible for glacial landforms and related sediments in the outer part of the amphitheater. The age of the younger advance fits the chronology of the culmination of the last glaciation in the Alps, well established between 24 and 21 cal ka BP (20 to 17.5 14C ka BP), whereas the first pulse between 26.5 and 23 cal ka BP (22 to 21 14C ka BP), previously undated, was usually related to older (pre-LGM) glaciations by previous authors. Here, the first pulse is the most extensive LGM culmination, but is often buried by the subsequent pulse. The onset and final recession of the late Würm Alpine glaciation in the Tagliamento amphitheater are synchronous with the established global glacial maximum between 30 and 19 cal ka BP. The two-fold LGM glacial oscillation is interpreted as a millennial-scale modulation within the late Würm glaciation, caused by oscillations in inputs of southerly atmospheric airflows related to Dansgaard-Oeschger cycles. Phases of enhanced southerly circulation promoted increased rainfall and ice accumulation in the southern Alps.

Monegato, Giovanni; Ravazzi, Cesare; Donegana, Marta; Pini, Roberta; Calderoni, Gilberto; Wick, Lucia

2007-09-01

80

Design of Serially Concatenated Trellis Coded Modulation  

NASA Technical Reports Server (NTRS)

Serial concatenation of an outer binary convolutional code with an inner TCM code over a multidimensional Euclidean constellation through an interleaver, allows to extend the extremely good performance of turbo codes to the case of high spectral efficiency.

Benedetto, S.; Divsalar, D.; Garello, R.; Montorsi, G.; Pollara, F.

1998-01-01

81

Monsters Inc.: Serial killers and consumer culture  

Microsoft Academic Search

Serial killing has become big business. Over the past 15 years, popular culture has been flooded by true-life crime stories, biographies, best-selling fiction, video games and television documentaries devoted to this subject. Cinema is the cultural space in which this phenomenon is perhaps most conspicuous. The Internet Movie Database (imdb.com) lists over 1000 films featuring serial killers and most of

Brian Jarvis

2007-01-01

82

Irreversibility in diluted antiferromagnets  

SciTech Connect

We compute the irreversibility phase diagram, and history-dependent magnetizations for diluted Ising antiferromagnets in three dimensions. We use an iterative mean-field technique which has proved quite successful for treating spin glasses. Motion of the domain walls as the magnetic field is varied at low temperature is also discussed. The onset of time-dependent long-range order and magnetization anomalies are predicted for certain regions of the H-T phase diagram from our studies of the free-energy surface. Our results are compared to those of the random field ferromagnet and spin glasses, which have the common feature that on the time scale of a physical measurement the system is trapped in a local minimum of the free-energy surface. Irreversibility then results primarily from the disappearance of a given minimum as the field or temperature are changed and not from tunneling or thermal activation processes.

Soukoulis, C.M.; Grest, G.S.; Ro, C.; Levin, K.

1985-04-15

83

Dilute magnetic topological semiconductors  

NASA Astrophysics Data System (ADS)

Replacing semiconductors with topological insulators, we propose the problem of dilute magnetic topological semiconductors. Performing the renormalization group analysis for an effective field theory, where doped magnetic impurities give rise to a spatially modulated random axion term, we find a novel insulator-metal transition from either a topological or band insulating phase to an inhomogeneously distributed Weyl metallic state with such insulating islands, where extremely broad distributions of ferromagnetic clusters combined with strong spin-orbit interactions are responsible for the emergence of randomly distributed Weyl metallic islands. Since electromagnetic properties in a Weyl metal are described by axion electrodynamics, the role of random axion electrodynamics in transport phenomena casts an interesting problem beyond the physics of percolation in conventional disorder-driven metal-insulator transitions.

Kim, Kyoung-Min; Jho, Yong-Soo; Kim, Ki-Seok

2015-03-01

84

Standard dilution analysis.  

PubMed

Standard dilution analysis (SDA) is a novel calibration method that may be applied to most instrumental techniques that will accept liquid samples and are capable of monitoring two wavelengths simultaneously. It combines the traditional methods of standard additions and internal standards. Therefore, it simultaneously corrects for matrix effects and for fluctuations due to changes in sample size, orientation, or instrumental parameters. SDA requires only 200 s per sample with inductively coupled plasma optical emission spectrometry (ICP OES). Neither the preparation of a series of standard solutions nor the construction of a universal calibration graph is required. The analysis is performed by combining two solutions in a single container: the first containing 50% sample and 50% standard mixture; the second containing 50% sample and 50% solvent. Data are collected in real time as the first solution is diluted by the second one. The results are used to prepare a plot of the analyte-to-internal standard signal ratio on the y-axis versus the inverse of the internal standard concentration on the x-axis. The analyte concentration in the sample is determined from the ratio of the slope and intercept of that plot. The method has been applied to the determination of FD&C dye Blue No. 1 in mouthwash by molecular absorption spectrometry and to the determination of eight metals in mouthwash, wine, cola, nitric acid, and water by ICP OES. Both the accuracy and precision for SDA are better than those observed for the external calibration, standard additions, and internal standard methods using ICP OES. PMID:25599250

Jones, Willis B; Donati, George L; Calloway, Clifton P; Jones, Bradley T

2015-02-17

85

Dose reduction in CT with correlated-polarity noise reduction: context-dependent spatial resolution and noise properties demonstrating two-fold dose reduction with minimal artifacts  

NASA Astrophysics Data System (ADS)

Correlated-polarity noise reduction (CPNR) is a novel noise reduction technique that uses a statistical approach to reducing noise while maintaining excellent spatial resolution and a traditional noise appearance. It was demonstrated in application to CT imaging for the first time at SPIE 2013 and showed qualitatively excellent image quality at half of normal CT dose. In this current work, we measure quantitatively the spatial resolution and noise properties of CPNR in CT imaging. To measure the spatial resolution, we developed a metrology approach that is suitable for nonlinear algorithms such as CPNR. We introduce the formalism of Signal Modification Factor, SMF(u,v), which is the ratio in frequency space of the CPNR-processed image divided by the noise-free image, averaged over an ensemble of ROIs in a given anatomical context. SMF is a nonlinear analog to the MTF. We used XCAT computer-generated anthropomorphic phantom images followed by projection space processing with CPNR. The SMF revealed virtually no effect from CPNR on spatial resolution of the images (<7% degradation at all frequencies). Corresponding contextdependent NPS measurements generated with CPNR at half-dose were about equal to the NPS of full-dose images without CPNR. This result demonstrates for the first time the quantitative determination of a two-fold reduction in dose with CPNR with less than 7% reduction in spatial resolution. We conclude that CPNR shows strong promise as a method for reduction of noise (and hence, dose) in CT. CPNR may also be used in combination with iterative reconstruction techniques for yet further dose reduction, pending further investigation.

Dobbins, James T.; Wells, Jered R.; Segars, W. Paul

2014-03-01

86

Bicosomes: Bicelles in Dilute Systems  

Microsoft Academic Search

Bicelles are discoidal phospholipid nanostructures at high lipid concentrations. Under dilute conditions, bicelles become larger and adopt a variety of morphologies. This work proposes a strategy to preserve the discoidal morphology of bicelles in environments with high water content. Bicelles were formed in concentrated conditions and subsequently encapsulated in liposomes. Later dilution of these new structures, called bicosomes, demonstrated that

Gelen Rodríguez; Guadalupe Soria; Elisenda Coll; Laia Rubio; Lucyanna Barbosa-Barros; Carmen López-Iglesias; Anna M. Planas; Joan Estelrich; Alfons de la Maza; Olga López

2010-01-01

87

Isotope dilution mass spectrometry  

NASA Astrophysics Data System (ADS)

In the past isotope dilution mass spectrometry (IDMS) has usually been applied using the formation of positive thermal ions of metals. Especially in calibrating other analytical methods and for the certification of standard reference materials this type of IDMS became a routine method. Today, the progress in this field lies in the determination of ultra trace amounts of elements, e.g. of heavy metals in Antarctic ice and in aerosols in remote areas down to the sub-pg g-1 and sub-pg m-3 levels respectively, in the analysis of uranium and thorium at concentrations of a few pg g-1 in sputter targets for the production of micro- electronic devices or in the determination of sub-picogram amounts of230Th in corals for geochemical age determinations and of226Ra in rock samples. During the last few years negative thermal ionization IDMS has become a frequently used method. The determination of very small amounts of selenium and technetium as well as of other transition metals such as vanadium, chromium, molybdenum and tungsten are important examples in this field. Also the measurement of silicon in connection with a re-determination of Avogadro's number and osmium analyses for geological age determinations by the Re/Os method are of special interest. Inductively-coupled plasma mass spectrometry is increasingly being used for multi-element analyses by the isotope dilution technique. Determinations of heavy metals in samples of marine origin are representative examples for this type of multi-element analysis by IDMS. Gas chromatography-mass spectrometry systems have also been successfully applied after chelation of metals (for example Pt determination in clinical samples) or for the determination of volatile element species in the environment, e.g. dimethyl sulfide. However, IDMS--specially at low concentration levels in the environment--seems likely to be one of the most powerful analytical methods for speciation in the future. This has been shown, up to now, for species of iodine, selenium and some heavy metals in aquatic systems.

Heumann, Klaus G.

1992-09-01

88

Stress in dilute suspensions  

NASA Technical Reports Server (NTRS)

Generally, two types of theory are used to describe the field equations for suspensions. The so-called postulated equations are based on the kinetic theory of mixtures, which logically should give reasonable equations for solutions. The basis for the use of such theory for suspensions is tenuous, though it at least gives a logical path for mathematical arguments. It has the disadvantage that it leads to a system of equations which is underdetermined, in a sense that can be made precise. On the other hand, the so-called averaging theory starts with a determined system, but the very process of averaging renders the resulting system underdetermined. A third type of theory is proposed in which the kinetic theory of gases is used to motivate continuum equations for the suspended particles. This entails an interpretation of the stress in the particles that is different from the usual one. Classical theory is used to describe the motion of the suspending medium. The result is a determined system for a dilute suspension. Extension of the theory to more concentrated systems is discussed.

Passman, Stephen L.

1989-01-01

89

40 CFR 1065.240 - Dilution air and diluted exhaust flow meters.  

Code of Federal Regulations, 2014 CFR

... 2014-07-01 false Dilution air and diluted exhaust flow meters...ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING PROCEDURES...Measurements § 1065.240 Dilution air and diluted exhaust flow...

2014-07-01

90

40 CFR 1065.240 - Dilution air and diluted exhaust flow meters.  

Code of Federal Regulations, 2010 CFR

... 2010-07-01 false Dilution air and diluted exhaust flow meters...ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING PROCEDURES...Measurements § 1065.240 Dilution air and diluted exhaust flow...

2010-07-01

91

40 CFR 1065.240 - Dilution air and diluted exhaust flow meters.  

Code of Federal Regulations, 2013 CFR

... 2013-07-01 false Dilution air and diluted exhaust flow meters...ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING PROCEDURES...Measurements § 1065.240 Dilution air and diluted exhaust flow...

2013-07-01

92

40 CFR 1065.240 - Dilution air and diluted exhaust flow meters.  

Code of Federal Regulations, 2012 CFR

... 2012-07-01 false Dilution air and diluted exhaust flow meters...ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING PROCEDURES...Measurements § 1065.240 Dilution air and diluted exhaust flow...

2012-07-01

93

40 CFR 1065.240 - Dilution air and diluted exhaust flow meters.  

Code of Federal Regulations, 2011 CFR

... 2011-07-01 false Dilution air and diluted exhaust flow meters...ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING PROCEDURES...Measurements § 1065.240 Dilution air and diluted exhaust flow...

2011-07-01

94

[The serial murder: a few theoretical perspectives].  

PubMed

Despite numbers of publications and effort to try to establish the definition, the classification, the epidemiology, the clinical aspects and the psychopathology of serial killers, a universal consensus seems to say the least. Crime, though reduced in some countries, appears to impact more and more consistent worldwide, generating controversial ideas and a multitude of possible explanations. The serial killer usually presents as a caucasian man, aged between 20 and 40 years, often embedded socially and in his family, but with serious psychiatric, personal and especially family history. Usually acting alone, the serial killer plans a crime well in advance, but sometimes within the scope of impulsivity for a minority, the victim not being previously selected. In the latter case, an actual mental illness like psychosis is found. It is clear from numerous psychopathological studies conducted so far that most serial killers are defined as psychopathic sexual sadists, whose childhood was difficult, if not flouted, punctuated by physical and psychological violence situations. In addition, pervasive fantasies combined with thoughts of death, sex and violence are as much in common with the original acts of which they are the instigators. Beyond a relentless media that is constantly watering the public with stories and pictures depicting them as such, serial killers remain an enigma. We can therefore attempt to answer the various questions raised by this phenomenon, the way these people operate and how we can curb the rise, thanks to the neurobiological and neurophysiological approaches that science offers us. PMID:21834446

Leistedt, S; Linkowski, P

2011-01-01

95

/ http://www.sciencemag.org/content/early/recent / 11 September 2014 / Page 1 / 10.1126/science.1256729 The hallmark of meiosis is a two-fold reduction in ploidy, which occurs  

E-print Network

.1126/science.1256729 The hallmark of meiosis is a two-fold reduction in ploidy, which occurs because one round of DNA replication is followed by two rounds of chromosome segregation. During meiosis I, sister chromatids uniquely co-migrate, thereby enabling segregation of homologous chromosomes. During meiosis II

Asbury, Chip

96

Why extreme dilutions reach non-zero asymptotes: a nanoparticulate hypothesis based on froth flotation.  

PubMed

Extreme dilutions, especially homeopathic remedies of 30c, 200c, and higher potencies, are prepared by a process of serial dilution of 1:100 per step. As a result, dilution factors of 10(60), 10(400), or even greater are achieved. Therefore, both the presence of any active ingredient and the therapeutic efficacy of these medicines have been contentious because the existence of even traces of the starting raw materials in them is inconceivable. However, physicochemical studies of these solutions have unequivocally established the presence of the starting raw materials in nanoparticulate form even in these extreme (super-Avogadro, >10(23)) dilutions. In this article, we propose and validate a hypothesis to explain how nanoparticles are retained even at such enormous dilution levels. We show that once the bulk concentration is below a threshold level of a few nanograms/milliliter (ng/mL), at the end of each dilution step, all of the nanoparticles levitate to the surface and are accommodated as a monolayer at the top. This dominant population at the air-liquid interface is preserved and carried to the subsequent step, thereby forming an asymptotic concentration. Thus, all dilutions are only apparent and not real in terms of the concentrations of the starting raw materials. PMID:23083226

Chikramane, Prashant S; Kalita, Dhrubajyoti; Suresh, Akkihebbal K; Kane, Shantaram G; Bellare, Jayesh R

2012-11-13

97

Dilution refrigeration for space applications  

NASA Technical Reports Server (NTRS)

Dilution refrigerators are presently used routinely in ground based applications where temperatures below 0.3 K are required. The operation of a conventional dilution refrigerator depends critically on the presence of gravity. To operate a dilution refrigerator in space many technical difficulties must be overcome. Some of the anticipated difficulties are identified in this paper and possible solutions are described. A single cycle refrigerator is described conceptually that uses forces other than gravity to function and the stringent constraints imposed on the design by requiring the refrigerator to function on the earth without using gravity are elaborated upon.

Israelsson, U. E.; Petrac, D.

1990-01-01

98

Stochastic modeling of a serial killer.  

PubMed

We analyze the time pattern of the activity of a serial killer, who during 12 years had murdered 53 people. The plot of the cumulative number of murders as a function of time is of "Devil's staircase" type. The distribution of the intervals between murders (step length) follows a power law with the exponent of 1.4. We propose a model according to which the serial killer commits murders when neuronal excitation in his brain exceeds certain threshold. We model this neural activity as a branching process, which in turn is approximated by a random walk. As the distribution of the random walk return times is a power law with the exponent 1.5, the distribution of the inter-murder intervals is thus explained. We illustrate analytical results by numerical simulation. Time pattern activity data from two other serial killers further substantiate our analysis. PMID:24721476

Simkin, M V; Roychowdhury, V P

2014-08-21

99

Serial multiplier arrays for parallel computation  

NASA Technical Reports Server (NTRS)

Arrays of systolic serial-parallel multiplier elements are proposed as an alternative to conventional SIMD mesh serial adder arrays for applications that are multiplication intensive and require few stored operands. The design and operation of a number of multiplier and array configurations featuring locality of connection, modularity, and regularity of structure are discussed. A design methodology combining top-down and bottom-up techniques is described to facilitate development of custom high-performance CMOS multiplier element arrays as well as rapid synthesis of simulation models and semicustom prototype CMOS components. Finally, a differential version of NORA dynamic circuits requiring a single-phase uncomplemented clock signal introduced for this application.

Winters, Kel

1990-01-01

100

Sea Urchin Embryology: Sperm Dilution  

NSDL National Science Digital Library

Lab directions for up to two 50 min periods and the last of the dilution labs. Includes set up information, materials, procedure, experimental design, things to observe, math possibilities, thought-provoking questions and an assessment.

PhD David Epel (Stanford U. Hopkins Marine Station)

2007-04-20

101

Sea Urchin Embryology: Simple Dilutions  

NSDL National Science Digital Library

Starting from a known concentration students learn to use dilutions to determine the concentration of an unknown. The following skills are used in this lesson: 1. making dilutions 2. reading the meter on a simple homemade spectrophotometer 3. keeping careful laboratory records 4. graphing on linear graph paper 5. determining an unknown concentration from known 6. using a colored filter to enhance contrast and sensitivity

PhD David Epel (Stanford U. Hopkins Marine Station)

2006-12-20

102

Serial ricinine levels in serum and urine after ricin intoxication.  

PubMed

Ricinine is an alkaloid present in the castor bean plant (Ricinus communis) that can be used as a biomarker for ricin poisoning. Serial ricinine levels are reported in the serum and urine of a patient suffering from intentional ricin intoxication. The patient was brought to the hospital 4 h after injection and oral intake of a castor bean extract, but died 38 h later, despite intensive medical care. Ricinine was isolated from the samples by solid-phase extraction and quantitatively determined by isotopic dilution liquid chromatography-mass spectrometry. The ricinine level in serum declined from 33 to 23 ng/mL between 10 and 29 h post-exposure. Three urine samples collected from 12 to 41 h after ricin intoxication showed ricinine concentrations in the range of 20-58 ng/mL. The creatinine corrected values (21-30 µg/g) indicated a concentration-time profile with a maximum ricinine level in urine between 12 and 29 h after exposure. PMID:23592744

Røen, Bent Tore; Opstad, Aase Mari; Haavind, Anniken; Tønsager, Janne

2013-06-01

103

Analysis of serial measurements in medical research  

Microsoft Academic Search

In medical research data are often collected serially on subjects. The statistical analysis of such data is often inadequate in two ways: it may fail to settle clinically relevant questions and it may be statistically invalid. A commonly used method which compares groups at a series of time points, possibly with t tests, is flawed on both counts. There may,

J. N. S. Matthews; D. G. Altman; M. J. Campbell; P. Royston

1990-01-01

104

Serial Position Curves in Free Recall  

ERIC Educational Resources Information Center

The scenario for free recall set out in Laming (2009) is developed to provide models for the serial position curves from 5 selected sets of data, for final free recall, and for multitrial free recall. The 5 sets of data reflect the effects of rate of presentation, length of list, delay of recall, and suppression of rehearsal. Each model…

Laming, Donald

2010-01-01

105

Differential Serialization for Optimized SOAP Performance  

Microsoft Academic Search

The SOAP protocol has emerged as a Web Service commu- nication standard, providing simplicity, robustness, and ex- tensibility. SOAP's relatively poor performance threatens to limit its usefulness, especially for high-performance scien- tic applications. The serialization of outgoing messages, which includes conversion of in-memory data types to XML- based string format and the packing of this data into mes- sage buffers,

Nayef Abu-ghazaleh; Michael J. Lewis; Madhusudhan Govindaraju

2004-01-01

106

A Serials Holdings List Using UNIX Refer.  

ERIC Educational Resources Information Center

Describes the production of an automated union list of serials holdings at minimal cost by a small consortium of state government libraries in Louisiana. Use of the UNIX Refer system without any modifications for data entry and production is described. (EM)

Boyce, Judith I.; Boyce, Bert R.

1987-01-01

107

Notes for Serials Cataloging. Second Edition.  

ERIC Educational Resources Information Center

Notes are indispensable to serials cataloging. Researchers, reference librarians, and catalogers regularly use notes on catalog records and, as the audience for these notes has expanded from the local library community to the global Internet community, the need for notes to be cogent, clear, and useful is greater than ever. This book is a…

Geer, Beverley, Ed.; Caraway, Beatrice L., Ed.

108

The catathymic crisis: An explanation of the serial killer  

Microsoft Academic Search

Various explanations have been proposed to explain the motivation of serial killers. This article proposes that the theory\\u000a of the Catathymic Crisis is an explanation that adds light to the “serial” nature of serial murder as well as an explanation\\u000a of why and how a person can become a serial killer. The theory of Catathymic Crisis was presented in 1937

Arthur H. Garrison; Senior Criminal Justice Planner

1996-01-01

109

Serial Position Markers in Space: Visuospatial Priming of Serial Order Working Memory Retrieval  

PubMed Central

Most general theories on serial order working memory (WM) assume the existence of position markers that are bound to the to-be-remembered items to keep track of the serial order. So far, the exact cognitive/neural characteristics of these markers have remained largely underspecified, while direct empirical evidence for their existence is mostly lacking. In the current study we demonstrate that retrieval from verbal serial order WM can be facilitated or hindered by spatial cuing: begin elements of a verbal WM sequence are retrieved faster after cuing the left side of space, while end elements are retrieved faster after cuing the right side of space. In direct complement to our previous work—where we showed the reversed impact of WM retrieval on spatial processing—we argue that the current findings provide us with a crucial piece of evidence suggesting a direct and functional involvement of space in verbal serial order WM. We outline the idea that serial order in verbal WM is coded within a spatial coordinate system with spatial attention being involved when searching through WM, and we discuss how this account can explain several hallmark observations related to serial order WM. PMID:25611595

De Belder, Maya; Abrahamse, Elger; Kerckhof, Emma; Fias, Wim; van Dijck, Jean-Philippe

2015-01-01

110

Serial Publications Section. Collections and Services Division. Papers.  

ERIC Educational Resources Information Center

Papers on the acquisition and cataloging of serials presented at the 1982 International Federation of Library Associations (IFLA) conference include: (1) "CONSER (CONversion of SERials): What It Is and How It Works," a description by Barrie A. F. Burns (Canada) of a North American cooperative serials cataloging project and its origins, management,…

International Federation of Library Associations, The Hague (Netherlands).

111

Magnetic Particle Recovery of Serial Numbers  

SciTech Connect

One method used by crime labs to recover obliterated serial numbers in steel firearms (ferrous samples) is the magnetic particle technique. The use of this method is predicated on the detection of metal deformation present under stamped serial numbers after the visible stamp has been removed. Equipment specialized for this detection is not used in these attempts; a portable magnetic yoke used typically for flaw detection on large weldments or structures, along with dry visible magnetic powders, have been the tools of criminologists working in this area. Crime labs have reported low success rates using these tools [1, 2]. This is not surprising when one considers that little formal development has apparently evolved for use in such investigations since the publication of seminal work in this area some time ago [3]. The aim of this project is to investigate specific aspects of magnetic particle inspection for serial number recovery. This includes attempts to understand the magnetic characteristics of different steels that affect their performance in the test, such as varying results for carbon steels and alloy steels after different thermal and forming treatments. Also investigated are the effects of the nature of the sample magnetization (AC, rectified DC, and true DC) and the use of various detection media, such as visible powders and fluorescent sprays, on test outcome. Additionally, some aspects of surface preparation of firearm samples prior to number recovery were included in this work. The scope of this report includes a brief overview of the magnetic particle inspection method in general and its applications to forensic serial number recovery. This is followed by a description of how such investigations were simulated on lab samples, including a look at how the microstructure of a given steel will affect its performance in the test. Investigations into the serial number recovery in a series of ferromagnetic firearms (both steel and certain stainless steels) will then be presented. Recommendations for modifications to current approaches used in crime labs for serial number recovery, as well as suggestions for future work, conclude this document.

D. Utrata; M.J. Johnson

2003-10-01

112

Stochastic modeling of a serial killer  

E-print Network

We analyze the time pattern of the activity of a serial killer, who during twelve years had murdered 53 people. The plot of the cumulative number of murders as a function of time is of "Devil's staircase" type. The distribution of the intervals between murders (step length) follows a power law with the exponent of 1.4. We propose a model according to which the serial killer commits murders when neuronal excitation in his brain exceeds certain threshold. We model this neural activity as a branching process, which in turn is approximated by a random walk. As the distribution of the random walk return times is a power law with the exponent 1.5, the distribution of the inter-murder intervals is thus explained. We confirm analytical results by numerical simulation.

Simkin, M V

2012-01-01

113

Serial Endosymbiotic Theory (Set): The Biosemiotic Update  

Microsoft Academic Search

The Serial Endosymbiotic Theory explains the origin of nucleated eukaryotic cells by a merging of archaebacterial and eubacterial\\u000a cells. The paradigmatic change is that the driving force behind evolution is not ramification but merging. Lynn Margulis describes\\u000a the symbiogenetic processes in the language of mechanistic biology in such terms as “merging”, “fusion”, and “incorporation”.\\u000a Biosemiotics argues that all cell-cell interactions

Günther Witzany

2006-01-01

114

A Serial Prediction Component for Speech Timing  

Microsoft Academic Search

Durational serial interactions are not generallyincorporated into contemporary predictivemodels of timing for speech synthesis. In thisstudy, an anti-correlational factor applied atthe syllable level was identified for syllablelags occurring within roughly 500 ms. Asapplied to synthetic speech, a strongly anticorrelationaleffect appears to lend a pleasant,"swingy" effect to the speech output, while theabsence of such an effect results in a more"regimented" style

Eric Keller; Brigitte Zellner-keller

115

Droplet streams for serial crystallography of proteins  

Microsoft Academic Search

Serial diffraction of proteins requires an injection method to deliver analyte molecules—preferably uncharged, fully hydrated,\\u000a spatially oriented, and with high flux—into a focused probe beam of electrons or X-rays that is only a few tens of microns\\u000a in diameter. This work examines conventional Rayleigh sources and electrospray-assisted Rayleigh sources as to their suitability\\u000a for this task. A comparison is made

U. Weierstall; R. B. Doak; J. C. H. Spence; D. Starodub; D. Shapiro; P. Kennedy; J. Warner; G. G. Hembree; P. Fromme; H. N. Chapman

2008-01-01

116

Impedance Matching for a Serial Link Manipulator  

Microsoft Academic Search

We propose a new index for dynamic performance analysis of serial link manipulators named Impedance Matching Ellipsoid, or IME. Several indexes have been proposed for indicating static and dynamic performance of robot manipu- lators. For example, Dynamic Manipulability Ellipsoid (DME) characterizes distributions of hand acceleration produced by normalized joint torque. Manipulating-Force Ellipsoid (MFE) denotes static torque-force transmission ef£ciency from actuators

Ryo Kurazume; Tsutomu Hasegawa

2004-01-01

117

Dilution and the elusive baseline.  

PubMed

Knowledge of baseline conditions is critical for evaluating quantitatively the effect of human activities on environmental conditions, such as the impact of acid deposition. Efforts to restore ecosystems to prior, "pristine" condition require restoration targets, often based on some presumed or unknown baseline condition. Here, we show that rapid and relentless dilution of surface water chemistry is occurring in the White Mountains of New Hampshire, following decades of acid deposition. Extrapolating measured linear trends using a unique data set of up to 47 years, suggest that both precipitation and streamwater chemistry (r(2) >0.84 since 1985) in the Hubbard Brook Experimental Forest (HBEF) will approximate demineralized water within one to three decades. Because such dilute chemistry is unrealistic for surface waters, theoretical baseline compositions have been calculated for precipitation and streamwater: electrical conductivity of 3 and 5 ?S/cm, base cation concentrations of 7 and 39 ?eq/liter, acid-neutralizing capacity values of <1 and 14 ?eq/liter, respectively; and pH 5.5 for both. Significantly large and rapid dilution of surface waters to values even more dilute than proposed for Pre-Industrial Revolution (PIR) conditions has important ecological, biogeochemical and water resource management implications, such as for the success of early reproductive stages of aquatic organisms. PMID:22455659

Likens, Gene E; Buso, Donald C

2012-04-17

118

Botulinum toxin: dosing and dilution.  

PubMed

In the United States, the popularity of botulinum toxins as agents to treat muscle hypertonia has grown significantly over the last decade, despite lack of approval from the Food and Drug Administration for the indication of spasticity. Botox (botulinum toxin type A) and Myobloc (botulinum toxin type B) are Food and Drug Administration-approved for other indications, such as cervical dystonia. Another commercial preparation of type A, Dysport, has yet to reach the United States market as of this writing. Although botulinum toxin's efficacy in influencing spastic hypertonia is well accepted, the impact of certain clinical issues, such as dosing and dilution, on treatment outcome is not well established by published studies. This article will review important articles and selected abstracts on the use of botulinum toxin, specifically for spastic hypertonia in adults, with emphasis on current clinical practices as they relate to dosing and dilution. PMID:15448575

Francisco, Gerard E

2004-10-01

119

BASIC RESEARCH ON HIGH DILUTION EFFECTS  

Microsoft Academic Search

Basic research on high dilution effects started with homeopathic therapy. So many models have been tested that we have tried to classify them according to the general concept of regulation. Firstly, succussed dilutions must be separated from unsuccussed very low doses from a physical point of view. This leads us to discuss the validity of the controls in high dilution

MADELEINE BASTIDE

120

Science Notes: Dilution of a Weak Acid  

ERIC Educational Resources Information Center

This "Science note" arose out of practical work involving the dilution of ethanoic acid, the measurement of the pH of the diluted solutions and calculation of the acid dissociation constant, K[subscript a], for each diluted solution. The students expected the calculated values of K[subscript a] to be constant but they found that the…

Talbot, Christopher; Wai, Chooi Khee

2014-01-01

121

Cryogen-free dilution refrigerators  

NASA Astrophysics Data System (ADS)

We review briefly our first cryogen-free dilution refrigerator (CF-DR) which was precooled by a GM cryocooler. We then show how today's dry DRs with pulse tube precooling have developed. A few examples of commercial DRs are explained and noteworthy features pointed out. Thereby we describe the general advantages of cryogen-free DRs, but also show where improvements are still desirable. At present, our dry DR has a base temperature of 10 mK and a cooling capacity of 700 ?W at a mixing chamber temperature of 100 mK. In our cryostat, in most recent work, an additional refrigeration loop was added to the dilution circuit. This 4He circuit has a lowest temperature of about 1 K and a refrigeration capacity of up to 100 mW at temperatures slightly above 1 K; the dilution circuit and the 4He circuit can be run separately or together. The purpose of this additional loop is to increase the cooling capacity for experiments where the cooling power of the still of the DR is not sufficient to cool cold amplifiers and cables, e.g. in studies on superconducting quantum circuits or astrophysical applications.

Uhlig, K.

2012-12-01

122

Concurrent Cognitive Processes in Rat Serial Pattern Learning: Item Memory, Serial Position, and Pattern Structure  

ERIC Educational Resources Information Center

Three experiments examined the processes mediating rat serial pattern learning for rule-consistent versus rule-violating pattern elements ("violation elements"). In all three experiments, rats were trained to press retractable levers in a circular array in a specific sequence for brain-stimulation reward (BSR). Experiment 1 examined the role of…

Muller, Melissa D.; Fountain, Stephen B.

2010-01-01

123

HP's link interface chipset for Serial-HIPPI  

Microsoft Academic Search

A link interface chipset that conforms to the Serial-HIPPI (High-Performance Parallel Interface) specification is presented. The chipset contains all portions of the link interface and link control functions specified in Serial-HIPPI. The simple additional circuitry required to create a complete Serial-HIPPI link using this chipset is detailed. The two-chip set can also serve as a general-purpose link with no additional

W. McFarland; R. Walker; C. Stout; J. Wu; B. Lai; G. Kwan; C. Yen

1992-01-01

124

Representation of the serial killer on the Italian Internet.  

PubMed

The representation of serial killers was examined from the analysis of 317 Web pages in the Italian language to study how the psychological profiles of serial killers are described on the Italian Internet. The correspondence analysis of the content of these Web pages shows that in Italy the serial killer is associated with words such as "monster" and "horror," which suggest and imply psychological perversion and aberrant acts. These traits are peculiar for the Italian scenario. PMID:11783573

Villano, P; Bastianoni, P; Melotti, G

2001-10-01

125

Breaking the indexing ambiguity in serial crystallography.  

PubMed

In serial crystallography, a very incomplete partial data set is obtained from each diffraction experiment (a `snapshot'). In some space groups, an indexing ambiguity exists which requires that the indexing mode of each snapshot needs to be established with respect to a reference data set. In the absence of such re-indexing information, crystallographers have thus far resorted to a straight merging of all snapshots, yielding a perfectly twinned data set of higher symmetry which is poorly suited for structure solution and refinement. Here, two algorithms have been designed for assembling complete data sets by clustering those snapshots that are indexed in the same way, and they have been tested using 15,445 snapshots from photosystem I [Chapman et al. (2011), Nature (London), 470, 73-77] and with noisy model data. The results of the clustering are unambiguous and enabled the construction of complete data sets in the correct space group P63 instead of (twinned) P6322 that researchers have been forced to use previously in such cases of indexing ambiguity. The algorithms thus extend the applicability and reach of serial crystallography. PMID:24419383

Brehm, Wolfgang; Diederichs, Kay

2014-01-01

126

Galileo - The Serial-Production AIT Challenge  

NASA Technical Reports Server (NTRS)

The Galileo Project is one of the most demanding projects of ESA, being Europe's autarkic navigation system and a constellation composed of 30 satellites. This presentation points out the different phases of the project up to the full operational capability and the corresponding launch options with respect to launch vehicles as well as launch configurations. One of the biggest challenges is to set up a small serial 'production line' for the overall integration and test campaign of satellites. This production line demands an optimization of all relevant tasks, taking into account also backup and recovery actions. A comprehensive AIT concept is required, reflecting a tightly merged facility layout and work flow design. In addition a common data management system is needed to handle all spacecraft related documentation and to have a direct input-out flow for all activities, phases and positions at the same time. Process optimization is a well known field of engineering in all small high tech production lines, nevertheless serial production of satellites are still not the daily task in space business and therefore new concepts have to be put in place. Therefore, and in order to meet the satellites overall system optimization, a thorough interface between unit/subsystem manufacturing and satellite AIT must be realized to ensure a smooth flow and to avoid any process interruption, which would directly lead to a schedule impact.

Ragnit, Ulrike; Brunner, Otto

2008-01-01

127

Malignant sex and aggression: an overview of serial sexual homicide.  

PubMed

Serial murderers have attracted considerable attention in the popular press and criminal justice field, but scientific literature about these individuals is limited. This article provides an overview, from a psychiatric perspective, of serial sexual homicide, one type of serial killing. Characteristics of this type of murder and of these offenders are discussed. Defining qualities and diagnoses applicable to serial sexual killers are reviewed. Various etiologic theories are discussed, with emphasis on the role of fantasy and psychodynamic explanations. Governmental agencies involved in combating this type of crime, along with the role of mental health professionals in criminal profiling, are presented. Finally, the authors explore the reaction of society to this phenomenon. PMID:8054674

Myers, W C; Reccoppa, L; Burton, K; McElroy, R

1993-01-01

128

A psychological profile of a serial killer: a case report.  

PubMed

Serial killers have always fascinated society. A serial killer is typically defined as a perpetrator who murders three or more people over a period of time. Most reported cases of serial killers come from the United States and Canada. In India, there are few reported cases. We present, to the best of our knowledge, the first Indian case in the literature. The present case is of a 28-year-old man, Surinder Koli. The Department of Forensic Medicine & Toxicology, All India Institute of Medical Sciences, New Delphi handled the forensic study. We present a most unique psychological investigation into the mind of a serial killer. PMID:23115894

Dogra, T D; Leenaars, Antoon A; Chadha, R K; Manju, Mehta; Lalwani, Sanjeev; Sood, Mamta; Lester, David; Raina, Anupuma; Behera, C

2012-01-01

129

Serial binary interval ratios improve rhythm reproduction.  

PubMed

Musical rhythm perception is a natural human ability that involves complex cognitive processes. Rhythm refers to the organization of events in time, and musical rhythms have an underlying hierarchical metrical structure. The metrical structure induces the feeling of a beat and the extent to which a rhythm induces the feeling of a beat is referred to as its metrical strength. Binary ratios are the most frequent interval ratio in musical rhythms. Rhythms with hierarchical binary ratios are better discriminated and reproduced than rhythms with hierarchical non-binary ratios. However, it remains unclear whether a superiority of serial binary over non-binary ratios in rhythm perception and reproduction exists. In addition, how different types of serial ratios influence the metrical strength of rhythms remains to be elucidated. The present study investigated serial binary vs. non-binary ratios in a reproduction task. Rhythms formed with exclusively binary (1:2:4:8), non-binary integer (1:3:5:6), and non-integer (1:2.3:5.3:6.4) ratios were examined within a constant meter. The results showed that the 1:2:4:8 rhythm type was more accurately reproduced than the 1:3:5:6 and 1:2.3:5.3:6.4 rhythm types, and the 1:2.3:5.3:6.4 rhythm type was more accurately reproduced than the 1:3:5:6 rhythm type. Further analyses showed that reproduction performance was better predicted by the distribution pattern of event occurrences within an inter-beat interval, than by the coincidence of events with beats, or the magnitude and complexity of interval ratios. Whereas rhythm theories and empirical data emphasize the role of the coincidence of events with beats in determining metrical strength and predicting rhythm performance, the present results suggest that rhythm processing may be better understood when the distribution pattern of event occurrences is taken into account. These results provide new insights into the mechanisms underlining musical rhythm perception. PMID:23964258

Wu, Xiang; Westanmo, Anders; Zhou, Liang; Pan, Junhao

2013-01-01

130

Serial binary interval ratios improve rhythm reproduction  

PubMed Central

Musical rhythm perception is a natural human ability that involves complex cognitive processes. Rhythm refers to the organization of events in time, and musical rhythms have an underlying hierarchical metrical structure. The metrical structure induces the feeling of a beat and the extent to which a rhythm induces the feeling of a beat is referred to as its metrical strength. Binary ratios are the most frequent interval ratio in musical rhythms. Rhythms with hierarchical binary ratios are better discriminated and reproduced than rhythms with hierarchical non-binary ratios. However, it remains unclear whether a superiority of serial binary over non-binary ratios in rhythm perception and reproduction exists. In addition, how different types of serial ratios influence the metrical strength of rhythms remains to be elucidated. The present study investigated serial binary vs. non-binary ratios in a reproduction task. Rhythms formed with exclusively binary (1:2:4:8), non-binary integer (1:3:5:6), and non-integer (1:2.3:5.3:6.4) ratios were examined within a constant meter. The results showed that the 1:2:4:8 rhythm type was more accurately reproduced than the 1:3:5:6 and 1:2.3:5.3:6.4 rhythm types, and the 1:2.3:5.3:6.4 rhythm type was more accurately reproduced than the 1:3:5:6 rhythm type. Further analyses showed that reproduction performance was better predicted by the distribution pattern of event occurrences within an inter-beat interval, than by the coincidence of events with beats, or the magnitude and complexity of interval ratios. Whereas rhythm theories and empirical data emphasize the role of the coincidence of events with beats in determining metrical strength and predicting rhythm performance, the present results suggest that rhythm processing may be better understood when the distribution pattern of event occurrences is taken into account. These results provide new insights into the mechanisms underlining musical rhythm perception. PMID:23964258

Wu, Xiang; Westanmo, Anders; Zhou, Liang; Pan, Junhao

2013-01-01

131

Data Exploration Toolkit for serial diffraction experiments.  

PubMed

Ultrafast diffraction at X-ray free-electron lasers (XFELs) has the potential to yield new insights into important biological systems that produce radiation-sensitive crystals. An unavoidable feature of the `diffraction before destruction' nature of these experiments is that images are obtained from many distinct crystals and/or different regions of the same crystal. Combined with other sources of XFEL shot-to-shot variation, this introduces significant heterogeneity into the diffraction data, complicating processing and interpretation. To enable researchers to get the most from their collected data, a toolkit is presented that provides insights into the quality of, and the variation present in, serial crystallography data sets. These tools operate on the unmerged, partial intensity integration results from many individual crystals, and can be used on two levels: firstly to guide the experimental strategy during data collection, and secondly to help users make informed choices during data processing. PMID:25664746

Zeldin, Oliver B; Brewster, Aaron S; Hattne, Johan; Uervirojnangkoorn, Monarin; Lyubimov, Artem Y; Zhou, Qiangjun; Zhao, Minglei; Weis, William I; Sauter, Nicholas K; Brunger, Axel T

2015-02-01

132

Irish Serials in the Boston College Libraries  

NSDL National Science Digital Library

The Boston College Library system has online a searchable database of its noted Irish Serials collection. Researchers can now browse and search the list of over 1,400 newspapers, magazines, and journals that originate from or pertain to Ireland before deciding on whether to take a trip to Boston. The Libraries' holdings "range in date from 1685 to the present and cover Irish history, literature, politics, art, archaeology, economics, genealogy, music, and law." Users can search by title keyword, date range, or microform series. Search returns provide complete holdings information and a legend denoting microfiche or microform series. For example, NIPL denotes the Northern Ireland Political Literature series and IPRN (POST CW REP.) the Post Civil War Republican/Fianna Fail series.

133

Data Exploration Toolkit for serial diffraction experiments  

PubMed Central

Ultrafast diffraction at X-ray free-electron lasers (XFELs) has the potential to yield new insights into important biological systems that produce radiation-sensitive crystals. An unavoidable feature of the ‘diffraction before destruction’ nature of these experiments is that images are obtained from many distinct crystals and/or different regions of the same crystal. Combined with other sources of XFEL shot-to-shot variation, this introduces significant heterogeneity into the diffraction data, complicating processing and interpretation. To enable researchers to get the most from their collected data, a toolkit is presented that provides insights into the quality of, and the variation present in, serial crystallography data sets. These tools operate on the unmerged, partial intensity integration results from many individual crystals, and can be used on two levels: firstly to guide the experimental strategy during data collection, and secondly to help users make informed choices during data processing. PMID:25664746

Zeldin, Oliver B.; Brewster, Aaron S.; Hattne, Johan; Uervirojnangkoorn, Monarin; Lyubimov, Artem Y.; Zhou, Qiangjun; Zhao, Minglei; Weis, William I.; Sauter, Nicholas K.; Brunger, Axel T.

2015-01-01

134

EXPLOITING IMMUNOLOGICAL METAPHORS IN THE DEVELOPMENT OF SERIAL, PARALLEL, AND  

E-print Network

EXPLOITING IMMUNOLOGICAL METAPHORS IN THE DEVELOPMENT OF SERIAL, PARALLEL, AND DISTRIBUTED LEARNING;Abstract This thesis examines the use of immunological metaphors in building serial, parallel are placed in the context of this framework. An investigation into the use of immunological components

Kent, University of

135

The Effect of Concurrent Semantic Categorization on Delayed Serial Recall  

ERIC Educational Resources Information Center

The influence of semantic processing on the serial ordering of items in short-term memory was explored using a novel dual-task paradigm. Participants engaged in 2 picture-judgment tasks while simultaneously performing delayed serial recall. List material varied in the presence of phonological overlap (Experiments 1 and 2) and in semantic content…

Acheson, Daniel J.; MacDonald, Maryellen C.; Postle, Bradley R.

2011-01-01

136

PDA Serials: Practical and Policy Issues for Librarians  

ERIC Educational Resources Information Center

Personal Digital Assistant serials are not just a subset of electronic serials from an acquisitions/collection development point of view because of their total dependence on patron-owned technology. Even if viewed as a "free" resource there are issues of expense and effort involved in gathering, classifying, and providing access and awareness of…

Good, Stephen

2007-01-01

137

Serial Magnetization Transfer Imaging in Acute Optic Neuritis  

ERIC Educational Resources Information Center

In serial studies of multiple sclerosis lesions, reductions in magnetization transfer ratio (MTR) are thought to be due to demyelination and axonal loss, with later rises due to remyelination. This study followed serial changes in MTR in acute optic neuritis in combination with clinical and electrophysiological measurements to determine if the MTR…

Hickman, S. J.; Toosy, A. T.; Jones, S. J.; Altmann, D. R.; Miszkiel, K. A.; MacManus, D. G.; Barker, G. J.; Plant, G. T.; Thompson, A. J.; Miller, D.H.

2004-01-01

138

Serials Control and Deselection Projects. SPEC Kit 147.  

ERIC Educational Resources Information Center

This Systems and Procedures Exchange Center (SPEC) Kit on serials control and deselection projects provides a timely review of the efforts of research libraries to control the increasing costs of serial subscriptions. This kit contains documents from 13 libraries: University of California at Los Angeles and Riverside; Universities of Florida,…

Association of Research Libraries, Washington, DC. Office of Management Studies.

139

Indexing Serialized Fiction: May the Force Be with You.  

ERIC Educational Resources Information Center

The adult novel offers indexers an unusual opportunity to create a serialized fiction index. This research paper involved designing and creating a Character Index, Thesaurus, Glossary, and Abstract (with descriptors) for 21 novels based on the "Star Wars" movies. The novels are an unusual example of serialized fiction featuring main characters,…

Barr, Melissa M.

140

A Management Information System for Serials and Continuations.  

ERIC Educational Resources Information Center

Cutbacks in funding and personnel required the Mankato State College Library to gain more effective control over its serials collection. The task was to integrate the various data, some unrecorded, on standing orders and serials holdings and to produce for the library directors specialized lists of many types: all titles ordered from a specific…

Olson, Nancy B.; Lester, Daniel W.

141

Serially etched shark enameloid observed by incident light microscopy  

Microsoft Academic Search

Longitudinal and transverse tooth sections oïhums oxyrinchus were serially etched in 2.6% nitric acid. The changing optical properties of the etched surfaces were observed during the serial etchings, and the descent of the enameloid surfaces was measured. Shark enameloid seems to be less effectively etched by acid than human enamel; this difference may be due to differences in solubility between

Steinar Risnes; Gisle Fosse

1979-01-01

142

Using a Text-Processing Language for Serial Record Conversion.  

ERIC Educational Resources Information Center

Describes the automation of the machine-readable library serials file at Golda Meir Library, University of Wisconsin-Milwaukee. Highlights include purchase of the PERLINE/BOOKLINE system including a MARC interface module called MICA, five main aspects of the problem posed by the library serials conversion project, and use of the text-processing…

Lowrey, James R.; Hardiman, Paul V.

1985-01-01

143

Serial study of clinical and CT changes in tuberculous meningitis  

Microsoft Academic Search

Clinical and radiological changes in tuberculous meningitis (TBM) have been reported but there is paucity of comprehensive serial clinicoradiological follow-up. In this prospective hospital based study, we investigated serial changes in the clinical and radiological findings and their relationships over 6 months in 31 consecutive patients with TBM, diagnosed on the basis of clinical, radiological and spinal fluid criteria. We

P. Ranjan; J. Kalita; U. K. Misra

2003-01-01

144

The scene of the crime: inventing the serial killer  

Microsoft Academic Search

This article examines the meanings of the crime scene in serial killings, and the tensions between the real and the imagined in the circulation of those meanings. Starting with the Whitechapel Murders of 1888 it argues that they, as well as forming an origin for the construction of the identity of 'the serial killer', initiate certain ideas about the relationship

Alexandra Warwick

2008-01-01

145

Predicting Serial Killers' Home Base Using a Decision Support System  

Microsoft Academic Search

The effectiveness of a geographical decision support tool (Dragnet) forlocating the base of serial offenders was compared across 570 modelscomprised of a range of negative exponential functions, buffer zonecomponents, and normalization parameters. The models were applied to thebody disposal locations within each series for 70 U.S. serial killers. Twonormalization parameters were compared for all functions. The test ofeffectiveness was a

David Canter; Toby Coffey; Malcolm Huntley; Christopher Missen

2000-01-01

146

Antisocial personality disorder, sexual sadism, malignant narcissism, and serial murder.  

PubMed

This paper examines the research on serial murder and its relationship to antisocial personality disorder and sexual sadism. The concept of malignant narcissism is also discussed. Case studies of serial killers are examined regarding the nature of sexual violation and crime scene behavior. PMID:8988574

Geberth, V J; Turco, R N

1997-01-01

147

Forgetting in Immediate Serial Recall: Decay, Temporal Distinctiveness, or Interference?  

ERIC Educational Resources Information Center

Three hypotheses of forgetting from immediate memory were tested: time-based decay, decreasing temporal distinctiveness, and interference. The hypotheses were represented by 3 models of serial recall: the primacy model, the SIMPLE (scale-independent memory, perception, and learning) model, and the SOB (serial order in a box) model, respectively.…

Oberauer, Klaus; Lewandowsky, Stephan

2008-01-01

148

Serials Information on CD-ROM: A Reference Perspective.  

ERIC Educational Resources Information Center

Describes Ulrich's PLUS (a CD-ROM version of Ulrich's serials directories) and EBSCO's CD-ROM version of "The Serials Directory," and compares the two in terms of their use as reference tools. Areas discussed include database content, user aids, system features, search features, and a comparison of search results. Equipment requirements for both…

Karch, Linda S.

1990-01-01

149

The Application of Control Technology Based on Serial Port Communication  

Microsoft Academic Search

In this article data glove and mechanical arm are connected by RS-232 serial port line, so mechanical arm and data glove are very critical in the data transmission among computers. Under windows serial port communication can be realized in the two methods below: making use of ActiveX control and API communication function. In this passage the advantages and shortcomings of

Junjie Zhang; Wei Wei

2009-01-01

150

Regularization in Short-Term Memory for Serial Order  

ERIC Educational Resources Information Center

Previous research has shown that short-term memory for serial order can be influenced by background knowledge concerning regularities of sequential structure. Specifically, it has been shown that recall is superior for sequences that fit well with familiar sequencing constraints. The authors report a corresponding effect pertaining to serial…

Botvinick, Matthew; Bylsma, Lauren M.

2005-01-01

151

Dilute Acid and Autohydrolysis Pretreatment  

NASA Astrophysics Data System (ADS)

Exposure of cellulosic biomass to temperatures of about 120-210°C can remove most of the hemicellulose and produce cellulose-rich solids from which high glucose yields are possible with cellulase enzymes. Furthermore, the use of dilute sulfuric acid in this pretreatment operation can increase recovery of hemicellulose sugars substantially to about 85-95% of the maximum possible versus only about 65% if no acid is employed. The use of small-diameter tubes makes it possible to employ high solids concentrations similar to those preferred for commercial operations, with rapid heat-up, good temperature control, and accurate closure of material balances. Mixed reactors can be employed to pretreat larger amounts of biomass than possible in such small-diameter tubes, but solids concentrations are limited to about 15% or less to provide uniform temperatures. Pretreatment of large amounts of biomass at high solids concentrations is best carried out using direct steam injection and rapid pressure release, but closure of material balances in such “steam gun” devices is more difficult. Although flow of water alone or containing dilute acid is not practical commercially, such flow-through configurations provide valuable insight into biomass deconstruction kinetics not possible in the batch tubes, mixed reactors, or steam gun systems.

Yang, Bin; Wyman, Charles E.

152

A Microgravity Helium Dilution Cooler  

NASA Technical Reports Server (NTRS)

We are developing a He-3-He-4 dilution cooler to operate in microgravity. It uses charcoal adsorption pumps and heaters for its operation; it has no moving parts. It currently operates cyclically to well below 0.1 K and we have designed a version to operate continuously. We expect that the continuous version will be able to provide the long-duration cooling that many experiments need at temperatures down to 0.040 K. More importantly, such a dilution cooler could provide the precooling that enables the use of adiabatic demagnetization techniques that can reach temperatures below 0.001 K. At temperatures below 0.002 K many fascinating microgravity experiments on superfluid He-3 become possible. Among the possibilities are: research into a superfluid He-3 gyroscope, study of the nucleation of the B-phase of superfluid He-3 when the sample is floating out of contact with walls, study of the anisotropy of the surface tension of the B-phase, and NMR experiments on tiny free-floating clusters of superfluid He-3 atoms that should model the shell structure of nuclei.

Roach, Pat R.; Sperans, Joel (Technical Monitor)

1994-01-01

153

Short- and long-term memory contributions to immediate serial recognition: evidence from serial position effects.  

PubMed

A long-standing body of research supports the existence of separable short- and long-term memory systems, relying on phonological and semantic codes, respectively. The aim of the current study was to measure the contribution of long-term knowledge to short-term memory performance by looking for evidence of phonologically and semantically coded storage within a short-term recognition task, among developmental samples. Each experimental trial presented 4-item lists. In Experiment 1 typically developing children aged 5 to 6 years old showed evidence of phonologically coded storage across all 4 serial positions, but evidence of semantically coded storage at Serial Positions 1 and 2. In a further experiment, a group of individuals with Down syndrome was investigated as a test case that might be expected to use semantic coding to support short-term storage, but these participants showed no evidence of semantically coded storage and evidenced phonologically coded storage only at Serial Position 4, suggesting that individuals with Down syndrome have a verbal short-term memory capacity of 1 item. Our results suggest that previous evidence of semantic effects on "short-term memory performance" does not reflect semantic coding in short-term memory itself, and provide an experimental method for researchers wishing to take a relatively pure measure of verbal short-term memory capacity, in cases where rehearsal is unlikely. PMID:19672795

Purser, Harry; Jarrold, Christopher

2010-04-01

154

75 FR 59102 - Defense Federal Acquisition Regulation Supplement; Government-Assigned Serial Number Marking...  

Federal Register 2010, 2011, 2012, 2013, 2014

...Acquisition Regulation Supplement; Government- Assigned Serial Number Marking (DFARS...DFARS) to require contractors to apply Government-assigned serial numbers in human-readable...Background Contractors are required to apply Government-assigned serial numbers, such...

2010-09-27

155

75 FR 22727 - Defense Federal Acquisition Regulation Supplement; Government-Assigned Serial Number Marking...  

Federal Register 2010, 2011, 2012, 2013, 2014

...Acquisition Regulation Supplement; Government- Assigned Serial Number Marking (DFARS...DFARS) to require contractors to apply Government-assigned serial numbers in human-readable...274 to require contractors to apply Government-assigned serial numbers, such...

2010-04-30

156

A compact rotating dilution refrigerator  

E-print Network

We describe the design and performance of a new rotating dilution refrigerator that will primarily be used for investigating the dynamics of quantized vortices in superfluid 4He. All equipment required to operate the refrigerator and perform experimental measurements is mounted on two synchronously driven, but mechanically decoupled, rotating carousels. The design allows for relative simplicity of operation and maintenance and occupies a minimal amount of space in the laboratory. Only two connections between the laboratory and rotating frames are required for the transmission of electrical power and helium gas recovery. Measurements on the stability of rotation show that rotation is smooth to around 0.001 rad/s up to angular velocities in excess of 2.5 rad/s. The behavior of a high-Q mechanical resonator during rapid changes in rotation has also been investigated.

Fear, M J; Chorlton, D A; Zmeev, D E; Gillott, S J; Sellers, M C; Richardson, P P; Agrawal, H; Batey, G; Golov, A I

2013-01-01

157

Desynchronization in diluted neural networks  

SciTech Connect

The dynamical behavior of a weakly diluted fully inhibitory network of pulse-coupled spiking neurons is investigated. Upon increasing the coupling strength, a transition from regular to stochasticlike regime is observed. In the weak-coupling phase, a periodic dynamics is rapidly approached, with all neurons firing with the same rate and mutually phase locked. The strong-coupling phase is characterized by an irregular pattern, even though the maximum Lyapunov exponent is negative. The paradox is solved by drawing an analogy with the phenomenon of 'stable chaos', i.e., by observing that the stochasticlike behavior is 'limited' to an exponentially long (with the system size) transient. Remarkably, the transient dynamics turns out to be stationary.

Zillmer, Ruediger [INFN Sezione Firenze, via Sansone 1, I-50019 Sesto Fiorentino (Italy); Livi, Roberto [Dipartimento di Fisica, Universita di Firenze, via Sansone 1, I-50019 Sesto Fiorentino (Italy); Sezione INFN, Unita' INFM e Centro Interdipartimentale per lo Studio delle Dinamiche Complesse, via Sansone 1, I-50019 Sesto Fiorentino (Italy); Politi, Antonio; Torcini, Alessandro [Istituto dei Sistemi Complessi, CNR, CNR, via Madonna del Piano 10, I-50019 Sesto Fiorentino (Italy); Centro Interdipartimentale per lo Studio delle Dinamiche Complesse, via Sansone 1, I-50019 Sesto Fiorentino (Italy)

2006-09-15

158

Restoration of firearm serial numbers with electron backscatter diffraction (EBSD).  

PubMed

Firearm serial numbers are a critical identifying mark, and restoration of destroyed serial numbers is often crucial for prosecution of a criminal case. A method is presented utilizing electron backscatter diffraction (EBSD) in the scanning electron microscope (SEM) which allows for clear visualization of die-stamped imprints which have been completely polished away. Evidence of the stamp can be observed to a depth of approximately 760?m below the surface. With further development, the described method is capable of reconstructing an 8 character serial number in approximately 1h. PMID:25747326

White, Ryan M; Keller, Robert R

2015-04-01

159

Serial forced displacement in American cities, 1916-2010.  

PubMed

Serial forced displacement has been defined as the repetitive, coercive upheaval of groups. In this essay, we examine the history of serial forced displacement in American cities due to federal, state, and local government policies. We propose that serial forced displacement sets up a dynamic process that includes an increase in interpersonal and structural violence, an inability to react in a timely fashion to patterns of threat or opportunity, and a cycle of fragmentation as a result of the first two. We present the history of the policies as they affected one urban neighborhood, Pittsburgh's Hill District. We conclude by examining ways in which this problematic process might be addressed. PMID:21607786

Fullilove, Mindy Thompson; Wallace, Rodrick

2011-06-01

160

Charge-coupled-device parallel-to-serial converter  

NASA Technical Reports Server (NTRS)

A CCD parallel-to-serial converter comprising two successions of charge transfer stages, recurrently side-loaded with respective ones of parallelly supplied charge packets, then serially unloaded by time-interleaved respective shift register operations. The charge packets converted to time-division-multiplexed serial form are supplied to a shared electrometer, and the electrometer response is de-multiplexed. Preferably, shift register operations are carried forward concurrently at the same rate, but with the final charge transfer stages clocked in phases staggered in time.

Tower, John R. (Inventor)

1987-01-01

161

Switch for serial or parallel communication networks  

DOEpatents

A communication switch apparatus and a method for use in a geographically extensive serial, parallel or hybrid communication network linking a multi-processor or parallel processing system has a very low software processing overhead in order to accommodate random burst of high density data. Associated with each processor is a communication switch. A data source and a data destination, a sensor suite or robot for example, may also be associated with a switch. The configuration of the switches in the network are coordinated through a master processor node and depends on the operational phase of the multi-processor network: data acquisition, data processing, and data exchange. The master processor node passes information on the state to be assumed by each switch to the processor node associated with the switch. The processor node then operates a series of multi-state switches internal to each communication switch. The communication switch does not parse and interpret communication protocol and message routing information. During a data acquisition phase, the communication switch couples sensors producing data to the processor node associated with the switch, to a downlink destination on the communications network, or to both. It also may couple an uplink data source to its processor node. During the data exchange phase, the switch couples its processor node or an uplink data source to a downlink destination (which may include a processor node or a robot), or couples an uplink source to its processor node and its processor node to a downlink destination.

Crosette, Dario B. (DeSoto, TX)

1994-01-01

162

Switch for serial or parallel communication networks  

DOEpatents

A communication switch apparatus and a method for use in a geographically extensive serial, parallel or hybrid communication network linking a multi-processor or parallel processing system has a very low software processing overhead in order to accommodate random burst of high density data. Associated with each processor is a communication switch. A data source and a data destination, a sensor suite or robot for example, may also be associated with a switch. The configuration of the switches in the network are coordinated through a master processor node and depends on the operational phase of the multi-processor network: data acquisition, data processing, and data exchange. The master processor node passes information on the state to be assumed by each switch to the processor node associated with the switch. The processor node then operates a series of multi-state switches internal to each communication switch. The communication switch does not parse and interpret communication protocol and message routing information. During a data acquisition phase, the communication switch couples sensors producing data to the processor node associated with the switch, to a downlink destination on the communications network, or to both. It also may couple an uplink data source to its processor node. During the data exchange phase, the switch couples its processor node or an uplink data source to a downlink destination (which may include a processor node or a robot), or couples an uplink source to its processor node and its processor node to a downlink destination. 9 figs.

Crosette, D.B.

1994-07-19

163

MEMS switch based serial reconfigurable OADM  

NASA Astrophysics Data System (ADS)

A micro-electromechanical systems (MEMS) switch based serial optical add/drop multiplexer (OADM) is demonstrated. This OADM consists of a few cascaded cells, each of which includes one 2 × 2 MEMS optical switch, a tunable fiber Bragg grating (FBG) filter and an optical circulator. Each cell can handle four consecutive channels with 100 GHz spacing. The modularization makes the network upgrading easy. Power consumption of such system is several milli-watts and the isolation between any two channels is greater than 30 dB. The in-plane MEMS optical switches are integrated on single chip and fabricated by deep reactive ion etching technology, whose driving voltage is only 30 V. A uniform metal layer is coated on the FBG by using sputter to obtain 2.9 nm center wavelength tuning range with a maximum injecting current of 12 mA. The MEMS technology makes the coupling and assembly of the switch, filter and circulator easy, precise, and reliable due to the fiber grooves. Various data formats can be added and/or dropped by the proposed OADM because it is bit-rate independent.

Li, J.; Liu, A. Q.; Zhong, W. D.; Zhang, Q. X.; Lu, C.

2004-01-01

164

Serial fluoroscopic evaluation of a pacing lead.  

PubMed

A recall of the Telectronics Accufix 330-801 atrial lead was issued in November 1994, because of fracture of the "J"-shaped retention wire. To assess the integrity of the retention wire, we have performed fluoroscopic screening on 209 patients with the Accufix 330-801 atrial lead in place. Cine films of all 135 patients originally classified as normal were reevaluated after the original screening. Eighty patients have undergone two serial fluoroscopic evaluations separated by 158 +/- 5.4 days. Nine retention wires originally classified as normal were reclassified as fracture without protrusion, and two were reclassified as fracture with protrusion when the original films were reevaluated. Eight of the 11 leads reclassified were screened during our first 2 days of fluoroscopic evaluation of this lead. Of the 80 patients who underwent a second fluoroscopic screening, 70 were initially classified as normal (9 of which were reclassified as described above), 1 fractured, and 9 indeterminate. There were no new fractures detected in this group, and the fractured retention wires did not appear to change during this observation period. We conclude that there is a definite learning curve associated with fluoroscopic evaluation of this lead, and continue to recommend that screening be performed by cardiologists experienced in fluoroscopic screening. Fractured retention wires remained stable in appearance during this observation time. No new retention wire fractures were detected; however, longer follow-up will be required before the incidence of retention wire fracture can be determined. PMID:8848401

Lloyd, M A; Hayes, D L; Holmes, D R

1996-04-01

165

Serial femtosecond crystallography: the first five years.  

PubMed

Protein crystallography using synchrotron radiation sources has had a tremendous impact on biology, having yielded the structures of thousands of proteins and given detailed insight into their mechanisms. However, the technique is limited by the requirement for macroscopic crystals, which can be difficult to obtain, as well as by the often severe radiation damage caused in diffraction experiments, in particular when using tiny crystals. To slow radiation damage, data collection is typically performed at cryogenic temperatures. With the advent of free-electron lasers (FELs) capable of delivering extremely intense femtosecond X-ray pulses, this situation appears to be remedied, allowing the structure determination of undamaged macromolecules using either macroscopic or microscopic crystals. The latter are exposed to the FEL beam in random orientations and their diffraction data are collected at cryogenic or room temperature in a serial fashion, since each crystal is destroyed upon a single exposure. The new approaches required for crystal growth and delivery, and for diffraction data analysis, including de novo phasing, are reviewed. The opportunities and challenges of SFX are described, including applications such as time-resolved measurements and the analysis of radiation damage-prone systems. PMID:25866661

Schlichting, Ilme

2015-03-01

166

Serial femtosecond crystallography: the first five years  

PubMed Central

Protein crystallography using synchrotron radiation sources has had a tremendous impact on biology, having yielded the structures of thousands of proteins and given detailed insight into their mechanisms. However, the technique is limited by the requirement for macroscopic crystals, which can be difficult to obtain, as well as by the often severe radiation damage caused in diffraction experiments, in particular when using tiny crystals. To slow radiation damage, data collection is typically performed at cryogenic temperatures. With the advent of free-electron lasers (FELs) capable of delivering extremely intense femtosecond X-ray pulses, this situation appears to be remedied, allowing the structure determination of undamaged macromolecules using either macroscopic or microscopic crystals. The latter are exposed to the FEL beam in random orientations and their diffraction data are collected at cryogenic or room temperature in a serial fashion, since each crystal is destroyed upon a single exposure. The new approaches required for crystal growth and delivery, and for diffraction data analysis, including de novo phasing, are reviewed. The opportunities and challenges of SFX are described, including applications such as time-resolved measurements and the analysis of radiation damage-prone systems.

Schlichting, Ilme

2015-01-01

167

À propos des dilutions homéopathiques des vaccins  

Microsoft Academic Search

Vaccine dilutions are used in homeopathy for different purposes, for example to limit the side effects of vaccines or to prevent diseases in certain cases. However, in the absence of any scientific information on how they work, vaccine dilutions prepared using homeopathic methods can in no circumstances be used in place of legal vaccination.

Marie-Noëlle Domalain; Florence Peyrefitte; Bernard Poitevin

2010-01-01

168

Hematological response of immunized and serially bled Japanese quail.  

PubMed

Sexually mature female Japanese quail (Coturnix coturnix japonica) were immunized by an intravenous injection with .5 ml of a 7.5% suspension of Chukar partridge (Alectoris graeca chukar) red blood cells (CRBC). Blood samples were collected either serially from one group of quail or a single time from separate groups of quail at 0 (nonimmunized), 3, 6, and 9 days post-immunization. Total anti-CRBC hemagglutinin titers (HA) were measured by a microhemagglutinin procedure. Selected hematological variables were also measured. Mean HA was not affected by serial blood sampling. Total erythrocyte numbers, percent hematocrit, and hemoglobin levels were depressed in serially bled quail at 3 days postimmunization. Reticulocytosis was found in serially bled quail at 6 days postimmunization. PMID:4048067

Gildersleeve, R P; Thaxton, J P; Galvin, M J; McRee, D I

1985-09-01

169

A Tale of Two Serials Catalogers: Their Education and Training.  

ERIC Educational Resources Information Center

Personal narrative of the experiences of two graduates of the same library school who each accepted a position as a serials cataloger in the same academic library, seven years apart. The similarities and differences in their experiences are discussed. (CLB)

Osmus, Lori L.; Boydston, Jeanne M. K.

1987-01-01

170

Serial stimuli in the acquisition of discriminated avoidance  

E-print Network

SERIAL STINULI 1N THE ACQUISITION OF DISCRIMINATED AVOIDANCE A Thesis by NARY KATHLEEN HILDBRAND Submitted to the Graduate College of Texas A 6 N University in partial fulfillment of the requirement for the degree of MASTER OF SCIENCE... in the Acquisition of Discriminated Avoidance (August 1971) Mary Kathleen Hildbrand, B. S. Sam Houston State University Directed by: Dr. James M. Elliott Thirty male Ss were presented serial stimuli in discriminated avoidance procedures and were divided into 5...

Hildbrand, Mary Kathleen

1971-01-01

171

Three more semantic serial position functions and a SIMPLE explanation.  

PubMed

There are innumerable demonstrations of serial position functions-with characteristic primacy and recency effects-in episodic tasks, but there are only a handful of such demonstrations in semantic memory tasks, and those demonstrations have used only two types of stimuli. Here, we provide three more examples of serial position functions when recalling from semantic memory. Participants were asked to reconstruct the order of (1) two cartoon theme song lyrics, (2) the seven Harry Potter books, and (3) two sets of movies, and all three demonstrations yielded conventional-looking serial position functions with primacy and recency effects. The data were well-fit by SIMPLE, a local distinctiveness model of memory that was originally designed to account for serial position effects in short- and long-term episodic memory. According to SIMPLE, serial position functions in both episodic and semantic memory tasks arise from the same type of processing: Items that are more separated from their close neighbors in psychological space at the time of recall will be better remembered. We argue that currently available evidence suggests that serial position functions observed when recalling items that are presumably in semantic memory arise because of the same processes as those observed when recalling items that are presumably in episodic memory. PMID:23263860

Kelley, Matthew R; Neath, Ian; Surprenant, Aimée M

2013-05-01

172

21 CFR 864.5240 - Automated blood cell diluting apparatus.  

Code of Federal Regulations, 2013 CFR

...2013-04-01 false Automated blood cell diluting apparatus. 864.5240 Section...Devices § 864.5240 Automated blood cell diluting apparatus. (a) Identification. An automated blood cell diluting apparatus is a fully...

2013-04-01

173

21 CFR 864.5240 - Automated blood cell diluting apparatus.  

Code of Federal Regulations, 2012 CFR

...2012-04-01 false Automated blood cell diluting apparatus. 864.5240 Section...Devices § 864.5240 Automated blood cell diluting apparatus. (a) Identification. An automated blood cell diluting apparatus is a fully...

2012-04-01

174

21 CFR 864.5240 - Automated blood cell diluting apparatus.  

Code of Federal Regulations, 2014 CFR

...2014-04-01 false Automated blood cell diluting apparatus. 864.5240 Section...Devices § 864.5240 Automated blood cell diluting apparatus. (a) Identification. An automated blood cell diluting apparatus is a fully...

2014-04-01

175

21 CFR 864.5240 - Automated blood cell diluting apparatus.  

Code of Federal Regulations, 2011 CFR

...2011-04-01 false Automated blood cell diluting apparatus. 864.5240 Section...Devices § 864.5240 Automated blood cell diluting apparatus. (a) Identification. An automated blood cell diluting apparatus is a fully...

2011-04-01

176

21 CFR 864.5240 - Automated blood cell diluting apparatus.  

Code of Federal Regulations, 2010 CFR

...2010-04-01 false Automated blood cell diluting apparatus. 864.5240 Section...Devices § 864.5240 Automated blood cell diluting apparatus. (a) Identification. An automated blood cell diluting apparatus is a fully...

2010-04-01

177

Long-Range Interactions Dilute Granular Systems  

E-print Network

in General . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 1.2 Intermolecular Forces algorithm for MD methods is developed that handles long-range forces in a computationally efficient between dissipation at contact and long-range repulsive/attractive forces in homogeneous dilute particle

Luding, Stefan

178

Comparison of microtiter broth dilution and agar dilution methods for susceptibility testing of Eikenella corrodens.  

PubMed

Eikenella corrodens is a slow-growing, capnophilic, gram-negative rod which often grows poorly in liquid media. Consequently, the agar dilution technique is the method of choice for susceptibility testing of E. corrodens. We report a new microtiter broth dilution method for susceptibility testing of E. corrodens which compared favorably with results obtained by the agar dilution technique. Minimal bactericidal concentrations correlated well with minimal inhibitory concentrations. PMID:6338819

Goldstein, E J; Cherubin, C E; Shulman, M

1983-01-01

179

N:\\redesign\\indexes\\Publications_RegisterOfSerialTitles.doc 1 A Partial Listing of Serial Publications of Illinois Institute of Technology  

E-print Network

\\Publications_RegisterOfSerialTitles.doc 2 1963 ­ 1969 IIT Reports 1992.009 1969 ­ 1975 Technology and Human Affairs 1998.132 1971 ­ 1973 IIT, Armour Institute of Technology See President's Report AIT In 1998.186 ? Annual Report of IIT (& IITRIN:\\redesign\\indexes\\Publications_RegisterOfSerialTitles.doc 1 A Partial Listing of Serial

Heller, Barbara

180

Genetic programming and serial processing for time series classification.  

PubMed

This work describes an approach devised by the authors for time series classification. In our approach genetic programming is used in combination with a serial processing of data, where the last output is the result of the classification. The use of genetic programming for classification, although still a field where more research in needed, is not new. However, the application of genetic programming to classification tasks is normally done by considering the input data as a feature vector. That is, to the best of our knowledge, there are not examples in the genetic programming literature of approaches where the time series data are processed serially and the last output is considered as the classification result. The serial processing approach presented here fills a gap in the existing literature. This approach was tested in three different problems. Two of them are real world problems whose data were gathered for online or conference competitions. As there are published results of these two problems this gives us the chance to compare the performance of our approach against top performing methods. The serial processing of data in combination with genetic programming obtained competitive results in both competitions, showing its potential for solving time series classification problems. The main advantage of our serial processing approach is that it can easily handle very large datasets. PMID:24032750

Alfaro-Cid, Eva; Sharman, Ken; Esparcia-Alcázar, Anna I

2014-01-01

181

Serially heterotransplanted human prostate tumours as an experimental model  

PubMed Central

Abstract Preclinical research on prostate cancer (PC) therapies uses several models to represent the human disease accurately. A common model uses patient prostate tumour biopsies to develop a cell line by serially passaging and subsequent implantation, in immunodeficient mice. An alternative model is direct implantation of patient prostate tumour biopsies into immunodeficient mice, followed by serial passage in vivo. The purpose of this review is to compile data from the more than 30 years of human PC serial heterotransplantation research. Serially heterotransplanted tumours are characterized by evaluating the histopathology of the resulting heterotransplants, including cellular differentiation, karyotype, marker expression, hormone sensitivity, cellular proliferation, metastatic potential and stromal and vascular components. These data are compared with the initial patient tumour specimen and, depending on available information, the patient’s clinical outcome was compared with the heterotransplanted tumour. The heterotansplant model is a more accurate preclinical model than older generation serially passaged or genetic models to investigate current and newly developed androgen-deprivation agents, antitumour compounds, anti-angiogenic drugs and positron emission tomography radiotracers, as well as new therapeutic regimens for the treatment of PC. PMID:19874422

Lopez-Barcons, Lluis-A

2010-01-01

182

The relationship between serial sexual murder and autoerotic asphyxiation.  

PubMed

This case series documents and examines the association between autoerotic asphyxiation, sadomasochism, and serial sexual murderers. Autoerotic asphyxiation, along with other paraphilias found in this population, is reviewed. Five cases of serial sexual killers who engaged in autoerotic asphyxiation were identified worldwide: four from the United States and one from Russia. Case reports for each are provided. All (100%) were found to have sexual sadism in addition to autoerotic asphyxiation. Furthermore, two (40%) had bondage fetishism, and two (40%) had transvestic fetishism, consistent with these paraphilias co-occurring in those with autoerotic asphyxiation. Overall the group averaged 4.0 lifetime paraphilias. Some possible relationships were observed between the offenders' paraphilic orientation and their modus operandi, e.g., all of these serial killers strangled victims-suggesting an association between their sadistic and asphyxiative paraphilic interests. The overlap of seemingly polar opposite paraphilias in this sample--sexual sadism and autoerotic asphyxiation--is explored from a historical and clinical perspective. Multiple commonalities shared between these five offenders and serial sexual murderers in general are addressed. A primary limitation of this study is its small sample size and empirical basis; the results may not be generalizable beyond the sample. The findings from this study support the supposition that crime scene behaviors often reflect paraphilic disturbances in those who commit serial sexual homicides. PMID:17980531

Myers, Wade C; Bukhanovskiy, Alexandr; Justen, Elle; Morton, Robert J; Tilley, John; Adams, Kenneth; Vandagriff, Virgil L; Hazelwood, Robert R

2008-04-01

183

Hardware Implementation of Serially Concatenated PPM Decoder  

NASA Technical Reports Server (NTRS)

A prototype decoder for a serially concatenated pulse position modulation (SCPPM) code has been implemented in a field-programmable gate array (FPGA). At the time of this reporting, this is the first known hardware SCPPM decoder. The SCPPM coding scheme, conceived for free-space optical communications with both deep-space and terrestrial applications in mind, is an improvement of several dB over the conventional Reed-Solomon PPM scheme. The design of the FPGA SCPPM decoder is based on a turbo decoding algorithm that requires relatively low computational complexity while delivering error-rate performance within approximately 1 dB of channel capacity. The SCPPM encoder consists of an outer convolutional encoder, an interleaver, an accumulator, and an inner modulation encoder (more precisely, a mapping of bits to PPM symbols). Each code is describable by a trellis (a finite directed graph). The SCPPM decoder consists of an inner soft-in-soft-out (SISO) module, a de-interleaver, an outer SISO module, and an interleaver connected in a loop (see figure). Each SISO module applies the Bahl-Cocke-Jelinek-Raviv (BCJR) algorithm to compute a-posteriori bit log-likelihood ratios (LLRs) from apriori LLRs by traversing the code trellis in forward and backward directions. The SISO modules iteratively refine the LLRs by passing the estimates between one another much like the working of a turbine engine. Extrinsic information (the difference between the a-posteriori and a-priori LLRs) is exchanged rather than the a-posteriori LLRs to minimize undesired feedback. All computations are performed in the logarithmic domain, wherein multiplications are translated into additions, thereby reducing complexity and sensitivity to fixed-point implementation roundoff errors. To lower the required memory for storing channel likelihood data and the amounts of data transfer between the decoder and the receiver, one can discard the majority of channel likelihoods, using only the remainder in operation of the decoder. This is accomplished in the receiver by transmitting only a subset consisting of the likelihoods that correspond to time slots containing the largest numbers of observed photons during each PPM symbol period. The assumed number of observed photons in the remaining time slots is set to the mean of a noise slot. In low background noise, the selection of a small subset in this manner results in only negligible loss. Other features of the decoder design to reduce complexity and increase speed include (1) quantization of metrics in an efficient procedure chosen to incur no more than a small performance loss and (2) the use of the max-star function that allows sum of exponentials to be computed by simple operations that involve only an addition, a subtraction, and a table lookup. Another prominent feature of the design is a provision for access to interleaver and de-interleaver memory in a single clock cycle, eliminating the multiple clock-cycle latency characteristic of prior interleaver and de-interleaver designs.

Moision, Bruce; Hamkins, Jon; Barsoum, Maged; Cheng, Michael; Nakashima, Michael

2009-01-01

184

A combination strategy for tracking the serial criminal  

NASA Astrophysics Data System (ADS)

We build a Geographic Profiling Model to generate the criminal's geographical profile, by combining two complementary strategies: the Spatial Distribution Strategy and the Probability Distance Strategy. In the first strategy, we designate the mean of all the known crime sites as the anchor point, and build a Standard Deviational Ellipse Model, considering the effect of landscape. In the second strategy, we take many factors such as the buffer zone and distance decay theory into consideration and calculate the probability of the offender's residence in a certain area by using the Bayesian Theorem and the Rossmo Algorithm. Then, we combine the result of two strategies and get three search areas suit different conditions of the police to track the serial criminal. Apply the model to the English serial killer Peter Sutcliffe's case, the calculation result shows that the model can effectively be used to track serial criminal.

He, Chuan; Zhang, Yuan-Biao; Wan, Jiadi; Yu, Wenjing

2010-08-01

185

Temporal isolation effects in recognition and serial recall.  

PubMed

Recent temporal distinctiveness models of memory predict that temporally isolated items will be recalled better than temporally crowded items. The effect has been found in some tasks (free recall, memory for serial order when report order is unconstrained, running memory span) but not in others (forward serial recall). Such results suggest that the attentional weighting given to a temporal dimension in memory may vary with task demands. Here, we find robust temporal isolation effects in recognition memory (Experiment 1) and a smaller isolation effect in forward serial recall when an open pool of items is used (Experiment 2). Analysis of 26 temporal isolation effects suggests that the phenomenon occurs in a range of tasks but is larger when it is useful to attend to a temporal dimension in memory. The overall pattern of results is taken to favor memory models that rely on multiple weighted dimensions in memory, one of which is temporal. PMID:20921098

Morin, Caroline; Brown, Gordon D A; Lewandowsky, Stephan

2010-10-01

186

In situ serial Laue diffraction on a microfluidic crystallization device.  

PubMed

Renewed interest in room-temperature diffraction has been prompted by the desire to observe structural dynamics of proteins as they function. Serial crystallography, an experimental strategy that aggregates small pieces of data from a large uniform pool of crystals, has been demonstrated at synchrotrons and X-ray free-electron lasers. This work utilizes a microfluidic crystallization platform for serial Laue diffraction from macroscopic crystals and proposes that a collection of small slices of Laue data from many individual crystals is a realistic solution to the difficulties in dynamic studies of irreversible biochemical reactions. PMID:25484843

Perry, Sarah L; Guha, Sudipto; Pawate, Ashtamurthy S; Henning, Robert; Kosheleva, Irina; Srajer, Vukica; Kenis, Paul J A; Ren, Zhong

2014-12-01

187

Serial murder in America: case studies of seven offenders.  

PubMed

This article summarizes and compares information on seven interviewed serial killers in an ongoing project designed to study similarities and differences among these individuals. The aim of this article is to increase our collective knowledge of the dynamics of serial murder by examining the perpetrators' backgrounds, as well as the unique ways in which they view themselves and the world around them. Although qualitative interview research alone is not sufficient to fully understand such behavior, it is useful in many ways. Some of the information discussed based on the seven offenders interviewed is compared with broader epidemiological studies, and the strengths and limitations of each type of research are discussed. PMID:15211559

Beasley, James O

2004-01-01

188

Mossbauer effect in dilute iron alloys  

NASA Technical Reports Server (NTRS)

The effects of variable concentration, x, of Aluminum, Germanium, and Lanthanum atoms in Iron lattice on various Mossbauer parameters was studied. Dilute binary alloys of (Fe-Al), (Fe-Ge), (Fe-Al) containing up to x = 2 a/o of the dilute constituent were prepared in the form of ingots and rolled to a thickness of 0.001 in. Mossbauer spectra of these targets were then studied in transmission geometry to measure changes in the hyperfine field, peak widths isomer shifts as well as the ratio of the intensities of peaks (1,6) to the intensities of peaks (2,5). It was shown that the concept of effective hyperfine structure field in very dilute alloys provides a useful means of studying the effects of progressively increasing the solute concentration on host lattice properties.

Singh, J. J.

1975-01-01

189

Diluted magnetic semiconductor nanowires exhibiting magnetoresistance  

DOEpatents

A method for is disclosed for fabricating diluted magnetic semiconductor (DMS) nanowires by providing a catalyst-coated substrate and subjecting at least a portion of the substrate to a semiconductor, and dopant via chloride-based vapor transport to synthesize the nanowires. Using this novel chloride-based chemical vapor transport process, single crystalline diluted magnetic semiconductor nanowires Ga.sub.1-xMn.sub.xN (x=0.07) were synthesized. The nanowires, which have diameters of .about.10 nm to 100 nm and lengths of up to tens of micrometers, show ferromagnetism with Curie temperature above room temperature, and magnetoresistance up to 250 Kelvin.

Yang, Peidong (El Cerrito, CA); Choi, Heonjin (Seoul, KR); Lee, Sangkwon (Daejeon, KR); He, Rongrui (Albany, CA); Zhang, Yanfeng (El Cerrito, CA); Kuykendal, Tevye (Berkeley, CA); Pauzauskie, Peter (Berkeley, CA)

2011-08-23

190

Can serial rapists be distinguished from one-off rapists?  

PubMed

There are investigative advantages to being able to determine early in a police investigation whether a rape has been committed by a serial or a one-off rapist. Previous research has found some differences in the crime-scene behaviors of serial and one-off rapists; however, this research suffers from the limitation of utilizing a sample of rapes within which there was a mixture of victim-offender relationships. To address this limitation, this study sampled 38 serial (two or more convictions) and 50 one-off (one conviction) stranger rapists and compared their crime scene behavior across four domains (control, sex, escape and style behaviors). Serial and one-off rapists differed in some control and sexual behaviors, in particular, in the type of victim targeted, the offense locations, methods of control and the sexual acts forced upon the victim. However, the results did not indicate a striking difference in the offending behavior of the two groups. The implications of these findings for criminal investigations are discussed. PMID:24723507

Slater, Chelsea; Woodhams, Jessica; Hamilton-Giachritsis, Catherine

2014-01-01

191

Serial Back-Plane Technologies in Advanced Avionics Architectures  

NASA Technical Reports Server (NTRS)

Current back plane technologies such as VME, and current personal computer back planes such as PCI, are shared bus systems that can exhibit nondeterministic latencies. This means a card can take control of the bus and use resources indefinitely affecting the ability of other cards in the back plane to acquire the bus. This provides a real hit on the reliability of the system. Additionally, these parallel busses only have bandwidths in the 100s of megahertz range and EMI and noise effects get worse the higher the bandwidth goes. To provide scalable, fault-tolerant, advanced computing systems, more applicable to today s connected computing environment and to better meet the needs of future requirements for advanced space instruments and vehicles, serial back-plane technologies should be implemented in advanced avionics architectures. Serial backplane technologies eliminate the problem of one card getting the bus and never relinquishing it, or one minor problem on the backplane bringing the whole system down. Being serial instead of parallel improves the reliability by reducing many of the signal integrity issues associated with parallel back planes and thus significantly improves reliability. The increased speeds associated with a serial backplane are an added bonus.

Varnavas, Kosta

2005-01-01

192

Paced auditory serial addition test: Adult norms and moderator variables  

Microsoft Academic Search

This study examined the performance of a sample of 821 healthy job applicants on the Paced Auditory Serial Addition Test (PASAT). Subjects had previously passed basic academic skills tests and physical examinations and were deemed free of cognitive impairment and medical illness. They were also motivated to perform well on cognitive tests. Gender, ethnicity, and education were not significant moderator

Arthur N. Wiens; Kristi H. Fuller; John R. Crossen

1997-01-01

193

FPGA based fast synchronous serial multi-wire links synchronization  

NASA Astrophysics Data System (ADS)

The paper debates synchronization method of multi-wire, serial link of constant latency, by means of pseudo-random numbers generators. The solution was designed for various families of FPGA circuits. There were debated synchronization algorithm and functional structure of parameterized transmitter and receiver modules. The modules were realized in VHDL language in a behavioral form.

Pozniak, Krzysztof T.

2013-10-01

194

Phonological Similarity in Serial Recall: Constraints on Theories of Memory  

ERIC Educational Resources Information Center

In short-term serial recall, similar-sounding items are remembered more poorly than items that do not sound alike. When lists mix similar and dissimilar items, performance on the dissimilar items is of considerable theoretical interest. Farrell and Lewandowsky [Farrell, S., & Lewandowsky, S. (2003). Dissimilar items benefit from phonological…

Lewandowsky, Stephan; Farrell, Simon

2008-01-01

195

Mixed-List Phonological Similarity Effects in Delayed Serial Recall  

ERIC Educational Resources Information Center

Recent experiments have shown that placing dissimilar items on lists of phonologically similar items enhances accuracy of ordered recall of the dissimilar items [Farrell, S., & Lewandowsky, S. (2003). Dissimilar items benefit from phonological similarity in serial recall. "Journal of Experimental Psychology: Learning, Memory, and Cognition," 29,…

Farrell, Simon

2006-01-01

196

Becoming the victim: Beyond sadism in serial sexual murderers  

Microsoft Academic Search

The behavior and characteristics of sexually sadistic serial murderers have been described primarily in relation to their paraphilic arousal to the control and torture of their victims. Sadistic sexual murderers who demonstrate both sadism and masochism have been described, but less is known about this type of offender. This article will review a number of hypotheses proposed to explain these

James L. Knoll; Robert R. Hazelwood

2009-01-01

197

Counterbalancing for Serial Order Carryover Effects in Experimental Condition Orders  

ERIC Educational Resources Information Center

Reactions of neural, psychological, and social systems are rarely, if ever, independent of previous inputs and states. The potential for serial order carryover effects from one condition to the next in a sequence of experimental trials makes counterbalancing of condition order an essential part of experimental design. Here, a method is proposed…

Brooks, Joseph L.

2012-01-01

198

Process to restore obliterated serial numbers on metal surfaces  

NASA Technical Reports Server (NTRS)

Metal smeared into grooves of serial numbers by grinding or filing can be cleaned out by process called cavitation. Ultrasonic vibrator generates very high frequency vibrations in water which create millions of microscopic bubbles. Cavitation bubbles impact metal surface at thousands of pounds per square inch pressure. Metal particles filling grooves are broken away.

Young, S. G.; Parker, B.; Chisum, W. J.

1974-01-01

199

Serial Murderers in Germany From 1945 to 1995  

Microsoft Academic Search

The total number of serial murderers who were convicted between 1945 and 1995 in the Federal Republic of Germany (N = 61) are described in terms of their characteristics, with reference to sociodemographics, family background, social integration, intellectual capability, and personality disorders. A comparison with a larger sample of German sin- gle murderers from a previous study shows that the

STEPHAN HARBORT; ANDREAS MOKROS

2001-01-01

200

Picture Detection in Rapid Serial Visual Presentation: Features or Identity?  

ERIC Educational Resources Information Center

A pictured object can be readily detected in a rapid serial visual presentation sequence when the target is specified by a superordinate category name such as "animal" or "vehicle". Are category features the initial basis for detection, with identification of the specific object occurring in a second stage (Evans & Treisman, 2005), or is…

Potter, Mary C.; Wyble, Brad; Pandav, Rijuta; Olejarczyk, Jennifer

2010-01-01

201

Hybrid ARQ using Serial Concatenated Convolutional Codes over Fading Channels  

E-print Network

throughput when used in a hybrid FEC/ARQ system. However, future research involving the search for efficientHybrid ARQ using Serial Concatenated Convolutional Codes over Fading Channels Naveen Chandran and Matthew C. Valenti Lane Department of Computer Science and Electrical Engineering West Virginia University

Valenti, Matthew C.

202

The Serial Effect on Internal and External Variables.  

ERIC Educational Resources Information Center

A study of concord phenomena in Rio de Janeiro spoken Portuguese found that, in the serial context, the linguistic system is so highly constrained that external, and even internal, influences are blocked. Authors conclude that strong constraints should be identified and further studies undertaken to understand the interplay of the diverse forces…

Scherre, Maria Marta Pereira; Naro, Anthony J.

1992-01-01

203

INVESTIGATION Coalescence-Time Distributions in a Serial Founder  

E-print Network

these models. We interpret the theoretical results in relation to their implications for human populationINVESTIGATION Coalescence-Time Distributions in a Serial Founder Model of Human Evolutionary reproduces a pattern that has been observed both in human genetic data and in simulations. Our formulas

Rosenberg, Noah

204

The Insanity Plea in the Case of a Serial Killer  

Microsoft Academic Search

The authors comment on society's approach to criminal responsibility in the past and at present, and on the M'Naghten, the Durham, and the American Law Institute definitions of legal sanity. Some statistical studies concerning the frequency and success of the insanity plea in the United States are reported. The recent case of a serial killer, examined by the first author

George B. Palermo; Richard D. Knudten

1994-01-01

205

Encounter and death : The spatial behavior of US serial killers  

Microsoft Academic Search

The locations at which each of 54 US serial killers, who had each killed at least ten people, first encountered their victims (PFE) and later dumped their bodies (BD) were examined in relation to the residence of the offender in order to test three hypotheses: the home tended to be a geographical focus for the crimes; the PFE is more

Maurice Godwin; David Canter

1997-01-01

206

Monsters in the Media; Portrayal of the Psychopathic Serial Killer  

Microsoft Academic Search

Abstract This study aims to investigate the way in which the media represent the phenomenon,of the serial killer who is suffering from psychopathic disorder. It reviews what constitutes a person suffering from psychopathy, giving an understanding and definition of the personality disorder. It then gives an insight into the language which is used by various media texts in order to

Danielle Jeffery

207

Child serial murder-psychodynamics: closely watched shadows.  

PubMed

There is a malignant transformation in object relations resulting in an identification with an omnipotent and cruel object resulting in an identity transformation. If the tension, desperation, and dissociation increase, serial murder becomes spree murder. The presence of pathological narcissism and psychopathic tendencies are of diagnostic significance in understanding the murderer's personality functioning and motivation to kill. Meloy (1988) considered the degree of sadism and aggression combined with narcissistic qualities to reflect the "malignancy" of the psychopathic disturbance where gratification (of aggression) occurs in the service of narcissistic functioning--that is, cruelty toward others in the form of a triumphant victory over a rejecting object. Meloy also believes that dissociation is ubiquitious in the psychopath. The initial murder of the serial murderer may reflect a "new identity." The pathological object-relations of narcissism and the malignant narcissism are important diagnostic indicators in the personality functioning of serial killers and the occurrence of these phenomena is a significant factor in the formation of the personalities of serial killers, their inner motivations, and their pattern of commission. PMID:11685995

Turco, R

2001-01-01

208

Serial Killers: Academic Libraries Respond to Soaring Costs.  

ERIC Educational Resources Information Center

Discusses ways in which academic libraries are responding to rising costs of serials. Topics addressed include pricing by publishers; the effect of journal cancellations on research activities; interlibrary loans and document delivery services; coordinated cancelling; electronic journals; and experiences at the University of Arizona. (LRW)

McCarthy, Paul

1994-01-01

209

An Enigmatic Personality: Case Report of a Serial Killer  

Microsoft Academic Search

This case report describes a man with aggressive and anti-social behaviors, a 47, XYY karyotype, abnormally elevated urinary kryptopyrroles and multiple brain injuries who is now serving a 250 year sentence for the serial murders of 11 women. These multiple abnormal findings have relevance as identifiable precursors for potential violence in such individuals with a history of behavioral disturbance and

Richard T. Kraus

210

DC and RF Measurements of Serial Bi-SQUID Arrays  

E-print Network

SQUID arrays are promising candidates for low profile antennas and low noise amplifier applications. We present the integrated circuit designs and results of DC and RF measurements of the wideband serial arrays based on integration of linear bi-SQUID cells forming a Superconducting Quantum Interference Filter (bi-SQUID SQIF). Various configurations of serial arrays designs are described. The measured linearity, power gain, and noise temperature are analyzed and compared. The experimental results are matched to results of mathematical modeling. A serial bi-SQUID SQIF arrays are mounted into a coplanar waveguide (CPW) and symmetrically grounded to corresponding sides of CPW. The RF output comes out from the central common line, which is also used for DC biasing and forms a symmetrical balanced output. The signal and DC flux biasing line is designed as coplanar lines passed in parallel over each bi-SQUID cell in a bidirectional fashion concentrating magnetic flux inside of each cell. Serial bi-SQUID SQIF arrays ...

Prokopenko, G V; de Escobar, A Leese; Taylor, B; de Andrade, M C; Berggren, S; Longhini, P; Palacios, A; Nisenoff, M; Fagaly, R L

2012-01-01

211

Haptic Manipulation of Serial-Chain Virtual Mechanisms  

Microsoft Academic Search

This paper presents an approach for providing realistic for ce feedback to users manipulating serial-chain virtual mechanisms. In the proposed approach, a haptic device controller is designed that penalizes users' motion along the directions resi sted by the virtual joints. The resisted directions span the null space the Jacobian of the virtual mechanism computed at the users' hand, and are

Daniela Constantinescu; Septimiu E. Salcudean; Elizabeth A. Croft

2006-01-01

212

When Temporal Isolation Benefits Memory for Serial Order  

ERIC Educational Resources Information Center

According to temporal distinctiveness models, items that are temporally isolated from their neighbors during list presentation are more distinct and thus should be recalled better. Contrary to that expectation of distinctiveness views, much recent evidence has shown that forward short-term serial recall is unaffected by temporal isolation. We…

Lewandowsky, Stephan; Nimmo, Lisa M.; Brown, Gordon D. A.

2008-01-01

213

Auditory Word Serial Recall Benefits from Orthographic Dissimilarity  

ERIC Educational Resources Information Center

The influence of orthographic knowledge has been consistently observed in speech recognition and metaphonological tasks. The present study provides data suggesting that such influence also pervades other cognitive domains related to language abilities, such as verbal working memory. Using serial recall of auditory seven-word lists, we observed…

Pattamadilok, Chotiga; Lafontaine, Helene; Morais, Jose; Kolinsky, Regine

2010-01-01

214

Phosphorus and calcium retention in serially harvested cattle  

Technology Transfer Automated Retrieval System (TEKTRAN)

Data from 3 serial harvest trials were utilized to calculate phosphorus and calcium retention in cattle. Trial 1 evaluated three rates of gain during a growing period followed by a common finishing diet utilizing British crossbred steers. Four steers were harvested from each treatment following th...

215

Benchmarking Usage Statistics in Collection Management Decisions for Serials  

ERIC Educational Resources Information Center

Usage statistics are an important metric for making decisions on serials. Although the University of Nevada, Las Vegas (UNLV) Libraries have been collecting usage statistics, the statistics had not frequently been used to make decisions and had not been included in collection development policy. After undergoing a collection assessment, the…

Tucker, Cory

2009-01-01

216

Dyslexia: The Effects of Visual Memory and Serial Recall.  

ERIC Educational Resources Information Center

Research on the role of visual memory and serial recall in dyslexia is reviewed. Findings touch on feature theory, which proposes that information is held in the form of "features," and that students for example learn to discriminate letters by marking certain identifiable aspects. Other studies are described which focus on speed of processing…

McIntyre, Thomas C.

217

Serial cardiorespiratory exercise testing in patients with congenital heart disease  

Microsoft Academic Search

Aerobic capacity of patients with different forms of congenital heart disease was serially evaluated in 79 patients and the evolution was correlated with the lesion and the level of daily activity. The patients were divided into six groups: patients with a small ventricular septal defect (VSD) with mini shunt (n=14), mild pulmonary valve stenosis with gradient n=12), mild to moderate

T. Reybrouck; R. Rogers; M. Weymans; M. Dumoulin; M. Vanhove; W. Daenen; L. Van der Hauwaert; M. Gewillig

1995-01-01

218

Serial Learning in Rats: A Test of Three Hypotheses  

ERIC Educational Resources Information Center

Findings obtained by providing rats with a single fixed series of events, A-B-C-..., often are equally compatible with three alternative serial learning interpretations: that the signal for items is (A) their position in the series (position view), (B) the prior item of the series (chaining view), and (C) one, two, or more prior items of the…

Capaldi, E. J.; Miller, Ronald Mellado

2004-01-01

219

The Circulation Analysis of Serial Use: Numbers Game or Key to Service?  

PubMed Central

The conventionally erected and reported circulation analysis of serial use in the individual and the feeder library is found to be statistically invalid and misleading, since it measures neither the intellectual use of the serial's contents nor the physical handlings of serial units, and is nonrepresentative of the in-depth library use of serials. It fails utterly to report or even to suggest the relation of intralibrary and interlibrary serial resources. The actual mechanics of the serial use analysis, and the active variables in the library situation which affect serial use, are demonstrated in a simulated analysis and are explained at length. A positive design is offered for the objective gathering and reporting of data on the local intellectual use and physical handling of serials and the relating of resources. Data gathering in the feeder library, and implications for the extension of the feeder library's resources, are discussed. PMID:6055863

Raisig, L. Miles

1967-01-01

220

Serials Management in the Electronic Era: Papers in Honor of Peter Gellatly, Founding Editor of "The Serials Librarian."  

ERIC Educational Resources Information Center

This book assesses progress and technical changes in the field of serials management and anticipates future directions and challenges for librarians. The book consists of 18 chapters: (1) "Introduction" (Jim Cole and James W. Williams); (2) "Peter Gellatly--Editor with a Deft Touch" (Ruth C. Carter); (3) "The "Deseret News" Web Edition" (Stewart…

Cole, Jim, Ed.; Williams, James W., Ed.

221

AN INITIAL DILUTION ZONE IMPACT ASSESSMENT  

E-print Network

of the Fraser River Estuary Monitoring Program (FREMP) Environmental Monitoring Program. The study consisted River. A reference site was established near the FREMP water quality monitoring station at Mission#12;AN INITIAL DILUTION ZONE IMPACT ASSESSMENT OF SELECTED INDUSTRIES IN THE FRASER RIVER ESTUARY

222

Zinc oxide based diluted magnetic semiconductors  

Microsoft Academic Search

During my graduate research I have synthesized materials known as diluted magnetic semiconductors (DMS) as epitaxial thin film structures using the process of pulsed laser deposition (PLD). These materials are envisioned to be of importance in the emerging field of spintronics where the charge as well as the spin of the charge carriers can be combined to yield unique functionalities

Shivaraman Ramachandran

2007-01-01

223

Soret and Dilution Effects on Premixed Flames  

Microsoft Academic Search

The structure of a wrinkled premixed flame is analysed theoretically. By assuming the reactive mixture diluted in an inert gas and a weak cross-diffusion coupling between the heat and mass fluxes, the effect of the change by the reaction of the physical gas properties (thermal conductivity, specific heat, number of molecules) and Soret and Dufour diffusions have been investigated in

PEDRO GARCÍA-YBARRA; COLETTE NICOLI; PAUL CLAVIN

1984-01-01

224

Resistance Minimum in Dilute Magnetic Alloys  

Microsoft Academic Search

Based on the s-d interaction model for dilute magnetic alloys we have calculated the scattering probability of the conduction electrons to the second Born approximation. Because of the dynamical character of the localized spin system, the Pauli principle should be taken into account in the intermediate states of the second order terms. Thus the effect of the Fermi sphere is

Jun Kondo

1964-01-01

225

Irradiated gases transferred without contamination or dilution  

NASA Technical Reports Server (NTRS)

Vacuum chamber apparatus opens sealed canisters of irradiated gases and transfers the contents without contaminating the surrounding area, and without diluting or polluting the contained gases. The apparatus consists of the chamber, a valved piping manifold, and a special drill and sealed drilling access.

Bonn, J. L.; Kern, W.

1967-01-01

226

Sulfuric Acid and Water: Paradoxes of Dilution  

ERIC Educational Resources Information Center

On equilibrium properties of aqueous solutions of sulfuric acid, Julius Thomsen has marked that the heat evolved on diluting liquid sulfuric acid with water is a continuous function of the water used, and excluded absolutely the acceptance of definite hydrates as existing in the solution. Information about thermochemical measurement, a discussion…

Leenson, I. A.

2004-01-01

227

Magnetic properties of diluted magnetic semiconductors  

NASA Astrophysics Data System (ADS)

A review will be given of the magnetic characteristics of diluted magnetic semiconductors and the relation with the driving exchange mechanisms. II-VI as well as IV-VI compounds will be considered. The relevance of the long-range interaction and the role of the carrier concentration will be emphasized.

de Jonge, W. J. M.; Swagten, H. J. M.

1991-11-01

228

ARE PARALLEL ROBOTS MORE ACCURATE THAN SERIAL ROBOTS? Sbastien Briot and Ilian A. Bonev  

E-print Network

ARE PARALLEL ROBOTS MORE ACCURATE THAN SERIAL ROBOTS? Sébastien Briot and Ilian A. Bonev _____________________________________________________________________________ ABSTRACT It is widely claimed that parallel robots are intrinsically more accurate than serial robots of serial- parallel 2-DOF planar robots. Only input errors are considered and all robots are optimized

Paris-Sud XI, Université de

229

Low-Stroke Actuation for a Serial Robot  

NASA Technical Reports Server (NTRS)

A serial robot includes a base, first and second segments, a proximal joint joining the base to the first segment, and a distal joint. The distal joint that joins the segments is serially arranged and distal with respect to the proximal joint. The robot includes first and second actuators. A first tendon extends from the first actuator to the proximal joint and is selectively moveable via the first actuator. A second tendon extends from the second actuator to the distal joint and is selectively moveable via the second actuator. The robot includes a transmission having at least one gear element which assists rotation of the distal joint when an input force is applied to the proximal and/or distal joints by the first and/or second actuators. A robotic hand having the above robot is also disclosed, as is a robotic system having a torso, arm, and the above-described hand.

Gao, Dalong (Inventor); Ihrke, Chris A. (Inventor)

2014-01-01

230

Dental identification in serial homicides: the Green River Murders.  

PubMed

At least 40 young women have died at the hands of a serial killer in what has been called the Green River Murders. Because most of the victims' remains were severely decomposed with partial or complete skeletonization and little or no personal effects were recovered, forensic odontologic methods played a key role in their identifications. Although numerous methods were used to accumulate leads to the identities of the badly decomposed skeletonized remains, leads generated through traditional investigative methods established the identities in most cases. Of 40 victims, 36 have now been identified, mainly by means of dental evidence. This article details the challenges presented by serial homicides and the key role of forensic odontologic methods in the Green River Murders investigation. PMID:2768702

Rothwell, B R; Haglund, W; Morton, T H

1989-09-01

231

Lipidic cubic phase serial millisecond crystallography using synchrotron radiation.  

PubMed

Lipidic cubic phases (LCPs) have emerged as successful matrixes for the crystallization of membrane proteins. Moreover, the viscous LCP also provides a highly effective delivery medium for serial femtosecond crystallography (SFX) at X-ray free-electron lasers (XFELs). Here, the adaptation of this technology to perform serial millisecond crystallography (SMX) at more widely available synchrotron microfocus beamlines is described. Compared with conventional microcrystallography, LCP-SMX eliminates the need for difficult handling of individual crystals and allows for data collection at room temperature. The technology is demonstrated by solving a structure of the light-driven proton-pump bacteriorhodopsin (bR) at a resolution of 2.4?Å. The room-temperature structure of bR is very similar to previous cryogenic structures but shows small yet distinct differences in the retinal ligand and proton-transfer pathway. PMID:25866654

Nogly, Przemyslaw; James, Daniel; Wang, Dingjie; White, Thomas A; Zatsepin, Nadia; Shilova, Anastasya; Nelson, Garrett; Liu, Haiguang; Johansson, Linda; Heymann, Michael; Jaeger, Kathrin; Metz, Markus; Wickstrand, Cecilia; Wu, Wenting; Båth, Petra; Berntsen, Peter; Oberthuer, Dominik; Panneels, Valerie; Cherezov, Vadim; Chapman, Henry; Schertler, Gebhard; Neutze, Richard; Spence, John; Moraes, Isabel; Burghammer, Manfred; Standfuss, Joerg; Weierstall, Uwe

2015-03-01

232

Lipidic cubic phase serial millisecond crystallography using synchrotron radiation  

PubMed Central

Lipidic cubic phases (LCPs) have emerged as successful matrixes for the crystallization of membrane proteins. Moreover, the viscous LCP also provides a highly effective delivery medium for serial femtosecond crystallography (SFX) at X-ray free-electron lasers (XFELs). Here, the adaptation of this technology to perform serial millisecond crystallography (SMX) at more widely available synchrotron microfocus beamlines is described. Compared with conventional microcrystallography, LCP-SMX eliminates the need for difficult handling of individual crystals and allows for data collection at room temperature. The technology is demonstrated by solving a structure of the light-driven proton-pump bacteriorhodopsin (bR) at a resolution of 2.4?Å. The room-temperature structure of bR is very similar to previous cryogenic structures but shows small yet distinct differences in the retinal ligand and proton-transfer pathway.

Nogly, Przemyslaw; James, Daniel; Wang, Dingjie; White, Thomas A.; Zatsepin, Nadia; Shilova, Anastasya; Nelson, Garrett; Liu, Haiguang; Johansson, Linda; Heymann, Michael; Jaeger, Kathrin; Metz, Markus; Wickstrand, Cecilia; Wu, Wenting; Båth, Petra; Berntsen, Peter; Oberthuer, Dominik; Panneels, Valerie; Cherezov, Vadim; Chapman, Henry; Schertler, Gebhard; Neutze, Richard; Spence, John; Moraes, Isabel; Burghammer, Manfred; Standfuss, Joerg; Weierstall, Uwe

2015-01-01

233

A constrained rasch model of trace redintegration in serial recall.  

PubMed

The notion that verbal short-term memory tasks, such as serial recall, make use of information in long-term as well as in short-term memory is instantiated in many models of these tasks. Such models incorporate a process in which degraded traces retrieved from a short-term store are reconstructed, or redintegrated (Schweickert, 1993), through the use of information in long-term memory. This article presents a conceptual and mathematical model of this process based on a class of item-response theory models. It is demonstrated that this model provides a better fit to three sets of data than does the multinomial processing tree model of redintegration (Schweickert, 1993) and that a number of conceptual accounts of serial recall can be related to the parameters of the model. PMID:18491497

Roodenrys, Steven; Miller, Leonie M

2008-04-01

234

Insect morphological diversification through the modification of wing serial homologs.  

PubMed

Fossil insects living some 300 million years ago show winglike pads on all thoracic and abdominal segments, which suggests their serial homology. It remains unclear whether winglike structures in nonwinged segments have been lost or modified through evolution. Here, we identified a ventral lateral part of the body wall on the first thoracic segment, the hypomeron, and pupal dorsolateral denticular outgrowths as wing serial homologs in the mealworm beetle Tenebrio molitor. Both domains transform into winglike structures under Hox RNA interference conditions. Gene expression and functional analyses revealed central roles for the key wing selector genes, vestigial and scalloped, in the hypomeron and the denticular outgrowth formation. We propose that modification, rather than loss, of dorsal appendages has provided an additional diversifying mechanism of insect body plan. PMID:23493422

Ohde, Takahiro; Yaginuma, Toshinobu; Niimi, Teruyuki

2013-04-26

235

Molluscan engrailed expression, serial organization, and shell evolution  

NASA Technical Reports Server (NTRS)

Whether the serial features found in some molluscs are ancestral or derived is considered controversial. Here, in situ hybridization and antibody studies show iterated engrailed-gene expression in transverse rows of ectodermal cells bounding plate field development and spicule formation in the chiton, Lepidochitona cavema, as well as in cells surrounding the valves and in the early development of the shell hinge in the clam, Transennella tantilla. Ectodermal expression of engrailed is associated with skeletogenesis across a range of bilaterian phyla, suggesting a single evolutionary origin of invertebrate skeletons. The shared ancestry of bilaterian-invertebrate skeletons may help explain the sudden appearance of shelly fossils in the Cambrian. Our interpretation departs from the consideration of canonical metameres or segments as units of evolutionary analysis. In this interpretation, the shared ancestry of engrailed-gene function in the terminal/posterior addition of serially repeated elements during development explains the iterative expression of engrailed genes in a range of metazoan body plans.

Jacobs, D. K.; Wray, C. G.; Wedeen, C. J.; Kostriken, R.; DeSalle, R.; Staton, J. L.; Gates, R. D.; Lindberg, D. R.

2000-01-01

236

[Some criminological and psychopathologic reflexions about serial crimes].  

PubMed

This article reviews the concept of serial crime, including murder as well as any action for the purpose of inflicting bodily harm upon any person. It characterizes three types of multi-murderers: serial killers, mass murderers, and spree killers. These offenders often have a specific (ritual) behavior that is idiosyncratic and repeated on each crime, which allows the psychological profiling of the murderer. Examples, a psychopathological background, and a description of both their criminal behavior and dynamics are provided for each of these criminals. They are further classified according to their different motivations: psychotic, prophetic or enlightened, pleasure, secondary or pecuniary profits, power or control. Finally, the author shares his personal experience over 20 years in the assessment of sexual offenders. PMID:22091451

Romi, Juan Carlos

2011-01-01

237

40 CFR 1065.667 - Dilution air background emission correction.  

Code of Federal Regulations, 2010 CFR

... 2010-07-01 false Dilution air background emission correction...ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING PROCEDURES...Requirements § 1065.667 Dilution air background emission...

2010-07-01

238

40 CFR 1065.667 - Dilution air background emission correction.  

Code of Federal Regulations, 2014 CFR

... 2014-07-01 false Dilution air background emission correction...ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING PROCEDURES...Requirements § 1065.667 Dilution air background emission...

2014-07-01

239

40 CFR 1065.667 - Dilution air background emission correction.  

Code of Federal Regulations, 2012 CFR

... 2012-07-01 false Dilution air background emission correction...ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING PROCEDURES...Requirements § 1065.667 Dilution air background emission...

2012-07-01

240

40 CFR 1065.667 - Dilution air background emission correction.  

Code of Federal Regulations, 2013 CFR

... 2013-07-01 false Dilution air background emission correction...ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING PROCEDURES...Requirements § 1065.667 Dilution air background emission...

2013-07-01

241

40 CFR 1066.610 - Dilution air background correction.  

Code of Federal Regulations, 2014 CFR

... 2014-07-01 false Dilution air background correction. 1066.610...ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS VEHICLE-TESTING PROCEDURES...Calculations § 1066.610 Dilution air background correction....

2014-07-01

242

40 CFR 1065.667 - Dilution air background emission correction.  

Code of Federal Regulations, 2011 CFR

... 2011-07-01 false Dilution air background emission correction...ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING PROCEDURES...Requirements § 1065.667 Dilution air background emission...

2011-07-01

243

Citation patterns in the health sciences: implications for serials/monographic fund allocation.  

PubMed

This study sought to determine optimal serial-to-monograph ratios for collection development by comparing citation frequency with current library practice. Internal medicine literature cited an average of 88% serial references and 12% monographs. In an observational study, teaching physicians on internal medicine rounds cited 89.5% serials and 10.5% monographs to student teams. By contrast, health sciences libraries included in the Houston statistics spend an average of 79% of acquisitions budgets for serials and 21% for monographs. An 88:12 acquisitions budget ratio would be more appropriate, reflecting actual use of serials and monographs in the health sciences. PMID:8428188

Burdick, A J; Butler, A; Sullivan, M G

1993-01-01

244

Efficient Iterative Decoding of Serially Concatenated Multiplexed Alamouti Codes  

Microsoft Academic Search

We present a low complexity iterative decoding method for a multiplexed Alamouti space-time code serially concatenated by a convolutional code. The space-time signalling code consists of a Gray coded 16-QAM mapper and two spatially overlaid Alamouti signalling blocks. A linear complexity decoder is used for decoding the inner space-time code. Ordinarily, an iterative decoding between the inner and outer decoders

Sudharshan Srinivasan; Linda M. Davis

2011-01-01

245

A new high rate serially concatenated space-time code  

Microsoft Academic Search

Using high rate recursive systematic convolutional code (RSCC) as the basic element and the trace criteria as the design principle, a new kind of high rate recursive space-time trellis code (HR-RSTTC) is designed for serial concatenation. By making the number of RSCCs and the coding rate of each RSCC be variable, our designed HR-RSTTC can adjust the data rate according

Ying Li; Xudong Guo; Junhong Hui; Xinmei Wang

2005-01-01

246

Two Serial Data to Pulse Code Modulation System Interfaces  

NASA Technical Reports Server (NTRS)

Two pulse code modulation (PCM) system interfaces for asynchronous serial data are described. One interface is for global positioning system (GPS) data on the NASA Dryden Flight Research Center (DFRC) F-15B (McDonnell Douglas Corporation, St. Louis, Missouri) airplane, tail number 836 (F-15B/836). The other is for flight control computer data on the duPont Aerospace (La Jolla, California) DP-1, a 53-percent scale model of the duPont Aerospace DP-2.

Hamory, Phil

2006-01-01

247

Serial partial sleep deprivation as adjuvant treatment of depressive insomnia  

Microsoft Academic Search

Hemmeter, Ulrich, Erich Seifritz, Martin Hatzinger, Matthias J. Müller and Edith Holsboer-Trachsler: Serial Partial Sleep Deprivation as Adjuvant Treatment of Depressive Insomnia. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 1995, 19(4): 593–602. 1.1. Sleep disturbance is a prominent symptom of major depression. Despite specific treatment with antidepressants, there is a substantial number of patients who improve in depressed mood but remain sleep

Ulrich Hemmeter; Erich Seifritz; Martin Hatzinger; Matthias J. Müller; Edith Holsboer-Trachsler

1995-01-01

248

Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography  

PubMed Central

Lipidic cubic phase (LCP) crystallization has proven successful for high-resolution structure determination of challenging membrane proteins. Here we present a technique for extruding gel-like LCP with embedded membrane protein microcrystals, providing a continuously-renewed source of material for serial femtosecond crystallography. Data collected from sub-10 ?m-sized crystals produced with less than 0.5 mg of purified protein yield structural insights regarding cyclopamine binding to the Smoothened receptor. PMID:24525480

Weierstall, Uwe; James, Daniel; Wang, Chong; White, Thomas A.; Wang, Dingjie; Liu, Wei; Spence, John C.H.; Doak, R. Bruce; Nelson, Garrett; Fromme, Petra; Fromme, Raimund; Grotjohann, Ingo; Kupitz, Christopher; Zatsepin, Nadia A.; Liu, Haiguang; Basu, Shibom; Wacker, Daniel; Han, Gye Won; Katritch, Vsevolod; Boutet, Sébastien; Messerschmidt, Marc; Williams, Garth J.; Koglin, Jason E.; Seibert, M. Marvin; Klinker, Markus; Gati, Cornelius; Shoeman, Robert L.; Barty, Anton; Chapman, Henry N.; Kirian, Richard A.; Beyerlein, Kenneth R.; Stevens, Raymond C.; Li, Dianfan; Shah, Syed T.A.; Howe, Nicole; Caffrey, Martin; Cherezov, Vadim

2014-01-01

249

A Radiation Tolerant Gigabit Serializer for LHC Data Transmission  

Microsoft Academic Search

In the future LHC experiments, some data acquisition and trigger links will be based on Gbit\\/s optical fiber networks. In this paper, a configurable radiation tolerant Gbit\\/s serializer (GOL) is presented that addresses the high-energy physics experiments requirements. The device can operate in four different modes that are a combination of two transmission protocols and two data rates (0.8 Gbit\\/s

P. Moreira; G. Cervelli; J. Christiansen; F. Faccio; A. Kluge; A. Marchioro; T. Toifl

250

Dynamic equalization during charging of serial energy storage elements  

Microsoft Academic Search

A technique is described that equalizes the amount of charge in a serial string of energy-storage cells during charging by using DC-to-DC converters to divert portions of the charging current past selected cells (or groups of cells). When no converters are operating, the charging current through the string is equal to that of the charging source. As the string charges,

D. C. Hopkins; C. R. Mosling; S. T. Hung

1993-01-01

251

Dynamic equalization during charging of serial energy storage elements  

Microsoft Academic Search

A technique is described that equalizes the amount of charge in a serial string of energy-storage cells during charging. The equalization is accomplished using dc-to-dc converters to divert portions of the charging current past selected cells (or groups of cells). When no converters are operating, the charging current through the string is equal to that of the charging source. As

D. C. Hopkins; C. R. Mosling; S. T. Hung

2009-01-01

252

Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography.  

PubMed

Lipidic cubic phase (LCP) crystallization has proven successful for high-resolution structure determination of challenging membrane proteins. Here we present a technique for extruding gel-like LCP with embedded membrane protein microcrystals, providing a continuously renewed source of material for serial femtosecond crystallography. Data collected from sub-10-?m-sized crystals produced with less than 0.5 mg of purified protein yield structural insights regarding cyclopamine binding to the Smoothened receptor. PMID:24525480

Weierstall, Uwe; James, Daniel; Wang, Chong; White, Thomas A; Wang, Dingjie; Liu, Wei; Spence, John C H; Bruce Doak, R; Nelson, Garrett; Fromme, Petra; Fromme, Raimund; Grotjohann, Ingo; Kupitz, Christopher; Zatsepin, Nadia A; Liu, Haiguang; Basu, Shibom; Wacker, Daniel; Han, Gye Won; Katritch, Vsevolod; Boutet, Sébastien; Messerschmidt, Marc; Williams, Garth J; Koglin, Jason E; Marvin Seibert, M; Klinker, Markus; Gati, Cornelius; Shoeman, Robert L; Barty, Anton; Chapman, Henry N; Kirian, Richard A; Beyerlein, Kenneth R; Stevens, Raymond C; Li, Dianfan; Shah, Syed T A; Howe, Nicole; Caffrey, Martin; Cherezov, Vadim

2014-01-01

253

Serial properties of behavior and their chemical modification  

Microsoft Academic Search

Certain features of operant behavior that are sensitive to the adverse effects of chemical exposure can be obscured by exclusive\\u000a experimental reliance on global measures such as response rate. Temporal patterning of behavior is the clearest example. Reinforcement\\u000a schedules studied in behavioral pharmacology and toxicology reveal novel consequences of chemical treatment when subjected\\u000a to analyses of their temporal and serial

Bernard Weiss; John M. Ziriax; M. Christopher Newland

1989-01-01

254

Module packaging for high-speed serial and parallel transmission  

Microsoft Academic Search

This paper discusses module packaging aspects with regard to high-speed data transmission for both single channel serial and multi channel parallel transmission. The increasing demand for bandwidth and data throughput of opto-electronic modules leads to continuously changing design rules for these modules. These rules are now completely different compared to those of the time of 100 Mbit\\/s transmission with light

Holger Karstensen; F. Auracher; Norbert Ebel; Jens Fiedler; Volker Plickert; Lutz Melchior; Lars Leininger; Manfred Bittner; Mario Festag; Markus Wicke; Stephan Meyer; Roger Miller; G. Kuhn; Hans-Ludwig Althaus; Alfred Ebberg

2000-01-01

255

Aspects of serial communication in a network of medical devices  

Microsoft Academic Search

Patient treatment in any hospital may require perfusion devices. Modern technology in this area is related to electronic-controlled devices that can be remotely accessed from a central place (guarding room). Because electromagnetic radiation is a big issue in medical world, remote access solutions must be wire-based, and RS485 serial communication is an effective solution. As part of a research project

Andrei Drumea; Alexandru Vasile

2006-01-01

256

A nonparametric trend test for seasonal data with serial dependence.  

USGS Publications Warehouse

Statistical tests for monotonic trend in seasonal (eg monthly) hydrologic time series are commonly confounded by some of the following problems: nonnormal data, missing values, seasonality, censoring and serial dependence. An extension of the Mann-Kendall test for trend (designed for such data) is presented here. Because the test is based entirely on tanks, it is robust against nonnormality and censoring.-from Authors

Hirsch, R.M.; Slack, J.R.

1984-01-01

257

A Comprehensive Website Meets the Serials Librarian's Back Issue Needs  

Microsoft Academic Search

The author describes USBE's Website, which meets virtually every back issue need of the serials librarian. An online catalog of over 17,000 scholarly journal title holdings, order page, membership application, and a fee-free out-of-print book search service are some of the features of the USBE site. The USBE Web pages also include instructions on how to donate surplus periodicals to

Victoria Z. Nann

1998-01-01

258

Seriality in Contemporary American Memoir: 1957-2007  

E-print Network

19 Fictional postmodern narratives also engage some of the features of serial self-representational texts, like the character of Nathan Zuckerman in Philip Roth?s novels. While many read Zuckerman as a stand- in for Roth himself, the books... are fiction, and Zuckerman is not Roth; however, Zuckerman works as a continuing character, across many texts, and is a figure to whom readers cling. As readers, we are engaged by particular characters and their stories, and we want to follow them...

McDaniel-Carder, Nicole Eve

2010-10-12

259

Serial reaction time performance following right parietal lobe damage  

PubMed Central

The serial reaction time task (SRT) is used to assess implicit sequence learning. Neuroimaging studies implicate parietal involvement, however, the necessity of this area is unclear. We tested six unilateral right parietal patients and compared their performance to matched controls. Both groups showed similar levels of learning and explicit awareness. Two patients with the largest lesions extending into either frontal or cerebellar regions showed no learning. These data suggest implicit sequence learning can occur despite damage to the right parietal lobe. PMID:19079745

Berryhill, M.E; Mazuz, Y; Olson, I.R

2008-01-01

260

Which serial killers commit suicide? An exploratory study.  

PubMed

In a sample of 483 serial killers, 6.2% were documented to have committed suicide. Those who committed suicide were found to come from more dysfunctional homes characterized by more psychiatric disturbance in the parents. The sexual acts involved in the murders by the suicides seemed to be more deviant in some aspects, such as committing more bizarre sexual acts or more often taping the murder. PMID:23131308

Lester, David; White, John

2012-11-30

261

Creating a Serial Database Using Subscription Agency Files  

Microsoft Academic Search

Subscription agency invoice files on diskette can be transferred into standard microcomputer database management packages to provide libraries with a fast low-cost serials database useful for various public or technical service functions and for management decision-making. Specific procedures are detailed for producing such a database using EBSCO Subscription Services invoice diskettes and the PC-File III and dBASE III PLUS database

Susan A. Cady

1988-01-01

262

A network-based Macintosh serial host interface program  

SciTech Connect

A program has been written for the Apple Macintosh to replace conventional host RS232 terminals with customizable user interfaces. Serial port NuBus cards in the Macintosh allow many simultaneous sessions to be maintained. A powerful system is attained by connecting multiple Macintoshes on a network, each running this program. Each is then able to share incoming data from any of its serial ports with any other Macintosh, as well as accept data from any other Macintosh for output to any of its serial ports. The program has been used to eliminate multiple host terminals, modernize the user interface, and to centralize operation of a complex control system. Minimal changes to host software have been required. By making extensive use of Macintosh resources, the same executable code serves in a variety of roles. An object oriented C language with a class library made the development straightforward and easy to modify. This program is used to control a 2 MW neutral beam system on the DIII-D magnetic fusion tokamak. 7 figs.

Wight, J.

1991-03-01

263

Serial extraction: 20 years of follow-up  

PubMed Central

This paper reports a case treated by a serial extraction program at the mixed dentition stage followed by a corrective orthodontic treatment, with a long-term follow-up period. Twenty years after the interceptive treatment, a harmonious face was observed along with treatment stability in the anterior posterior direction, deep overbite (which has been mentioned as a disadvantage of the serial extraction program), and a small relapse of anterior tooth crowding. All these conditions have been regarded as normal occurrences for most orthodontic treatments with a long-term follow-up period. This case report demonstrated that the establishment of a serial extraction protocol determined relevant esthetic changes that afforded an improvement of the patient's self-esteem, with a positive social impact. Furthermore, the low cost of this protocol permits the use of this therapy with underprivileged populations. It is important to emphasize that an early correction of tooth crowding by this protocol does not guarantee stability, but small relapses do not invalidate its accomplishment. PMID:23032213

de ALMEIDA, Renato Rodrigues; de ALMEIDA, Marcio Rodrigues; OLTRAMARI-NAVARRO, Paula Vanessa Pedron; CONTI, Ana Cláudia de Castro Ferreira; NAVARRO, Ricardo de Lima; de SOUZA, Karen Regina Siqueira

2012-01-01

264

Serial extraction: 20 years of follow-up.  

PubMed

This paper reports a case treated by a serial extraction program at the mixed dentition stage followed by a corrective orthodontic treatment, with a long-term follow-up period. Twenty years after the interceptive treatment, a harmonious face was observed along with treatment stability in the anterior posterior direction, deep overbite (which has been mentioned as a disadvantage of the serial extraction program), and a small relapse of anterior tooth crowding. All these conditions have been regarded as normal occurrences for most orthodontic treatments with a long-term follow-up period. This case report demonstrated that the establishment of a serial extraction protocol determined relevant esthetic changes that afforded an improvement of the patient's self-esteem, with a positive social impact. Furthermore, the low cost of this protocol permits the use of this therapy with underprivileged populations. It is important to emphasize that an early correction of tooth crowding by this protocol does not guarantee stability, but small relapses do not invalidate its accomplishment. PMID:23032213

Almeida, Renato Rodrigues de; Almeida, Marcio Rodrigues de; Oltramari-Navarro, Paula Vanessa Pedron; Conti, Ana Cláudia de Castro Ferreira; Navarro, Ricardo de Lima; Souza, Karen Regina Siqueira de

2012-01-01

265

The Effect of Concurrent Semantic Categorization on Delayed Serial Recall  

PubMed Central

The influence of semantic processing on the serial ordering of items in short-term memory was explored using a novel dual-task paradigm. Subjects engaged in two picture judgment tasks while simultaneously performing delayed serial recall. List material varied in the presence of phonological overlap (Experiments 1 and 2) and in semantic content (concrete words in Experiment 1 and 3; nonwords in Experiments 2 and 3). Picture judgments varied in the extent to which they required accessing visual semantic information (i.e., semantic categorization and line orientation judgments). Results showed that, relative to line orientation judgments, engaging in semantic categorization judgments increased the proportion of item ordering errors for concrete lists but did not affect error proportions for nonword lists. Furthermore, although more ordering errors were observed for phonologically similar relative to dissimilar lists, no interactions were observed between the phonological overlap and picture judgment task manipulations. These results thus demonstrate that lexical-semantic representations can affect the serial ordering of items in short-term memory. Furthermore, the dual-task paradigm provides a new method for examining when and how semantic representations affect memory performance. PMID:21058880

Acheson, Daniel J.; MacDonald, Maryellen C.; Postle, Bradley R.

2010-01-01

266

Functional morphology of serially linked skeletal muscle fibers.  

PubMed

In the skeletal muscle fiber organization of many vertebrate muscles, serial arrangements or linkages of muscle fibers along the muscle or fascicle are commonly found. These serially linked muscle fibers employ distinct junctional morphologies from muscle to muscle. Notable are the end-to-end linkages of muscle fibers through tendinous intersections (TIs), where many fibers end onto a continuous connective tissue plate with folded terminations similar to myotendinous junctions. Besides this end-to-end linkage, overlapping linkages or arrangements occur among nonspanning fibers terminating intrafascicularly. These nonspanning fibers bear tapering terminations with direct cell-cell (myomuscular) junctions or without any specialized junctions. Despite their overlapping linkages or tapering profiles, nonspanning fibers maintain a uniform sarcomere length along the linked fibers, suggesting that the overlapping-linked nonspanning fibers are equivalent to the end-to-end linked fibers in their mechanical capacity. However, the junctional compliance could differ in their extracellular elastic components and their organization at junctional sites, e.g., direct mechanical (myomuscular) junctions vs. indirect linkages through connective tissue. Increasing evidence suggests that the elastic components, including muscle fibers as well as connective tissues, are more critical than previously thought for the mode and/or the efficiency of tension transmission among serially arranged fibers and thus for the mechanical properties of the muscle. PMID:9575360

Hijikata, T; Ishikawa, H

1997-01-01

267

DDCMP protocol on a DMA serial-line board  

SciTech Connect

The Nuclear Chemistry Division of Lawrence Livermore National Laboratory is in the midst of an upgrade to their radiation counting facility. The result of this upgrade wil be a computer-based data acquisition network, the Nuclear Chemistry Counting Facility Network (NCCF-NET). This network will consist of forty dedicated LSI-11/2 based controllers, ten interactive LSI-11/23 based workstations and a VAX-11/750 central node for data reduction and storage. One of the data acquisition instruments used in this network is a Nuclear Data pulse-height analyzer, the ND66L. This analyzer communicates to a host system over a 9600-baud serial line, using the DDCMP link level protocol. In order to relieve the host computer from the overhead of handling the DDCMP protocol, an in-house designed DMA serial line board was implemented to communicate with the ND66L. The hardware used and its environment will be duscussed along with the design and implementation of the firmware, which implements the serial DDCMP link.

Hunt, D.N.; Kessler, G.C.

1982-01-01

268

SOAP Serialization Performance Enhancement, Design And Implementation Of A Middleware  

E-print Network

The most straightforward way to improve performance of any system is to define the bottlenecks and think of ways to remove them. Web services are the inseparable part of any web application, as a result enhancing performance of web services will have a great effect on the overall performance of the system. The most widely used communication protocol in the web services model, SOAP, is a simple protocol for the exchange of messages. The serialization of large SOAP responses is a major performance bottleneck in a SOAP message exchange. Clearly, some web servers can expect to receive many similar messages for a particular web service as they share the same signature. The idea behind this paper is to avoid the redundant serialization stage of SOAP responses for request which have the same call parameters. The technique exploits the similarities between call parameters to improve web service Response Time by avoiding redundant serialization of the same response with the help of a middleware running on top of web s...

Minaei, Behrouz

2009-01-01

269

The effect of concurrent semantic categorization on delayed serial recall.  

PubMed

The influence of semantic processing on the serial ordering of items in short-term memory was explored using a novel dual-task paradigm. Participants engaged in 2 picture-judgment tasks while simultaneously performing delayed serial recall. List material varied in the presence of phonological overlap (Experiments 1 and 2) and in semantic content (concrete words in Experiment 1 and 3; nonwords in Experiments 2 and 3). Picture judgments varied in the extent to which they required accessing visual semantic information (i.e., semantic categorization and line orientation judgments). Results showed that, relative to line-orientation judgments, engaging in semantic categorization judgments increased the proportion of item-ordering errors for concrete lists but did not affect error proportions for nonword lists. Furthermore, although more ordering errors were observed for phonologically similar relative to dissimilar lists, no interactions were observed between the phonological overlap and picture-judgment task manipulations. These results demonstrate that lexical-semantic representations can affect the serial ordering of items in short-term memory. Furthermore, the dual-task paradigm provides a new method for examining when and how semantic representations affect memory performance. PMID:21058880

Acheson, Daniel J; MacDonald, Maryellen C; Postle, Bradley R

2011-01-01

270

Cognitive, emotional and social markers of serial murdering.  

PubMed

Although criminal psychopathy is starting to be relatively well described, our knowledge of the characteristics and scientific markers of serial murdering is still very poor. A serial killer who murdered more than five people, KT, was administered a battery of standardized tests aimed at measuring neuropsychological impairment and social/emotional cognition deficits. KT exhibited a striking dissociation between a high level of emotional detachment and a low score on the antisocial behavior scale on the Psychopathy Checklist-Revised (PCL-R). The Minnesota Multiphasic Personality Inventory-2 showed a normal pattern with the psychotic triad at borderline level. KT had a high intelligence score and showed almost no impairment in cognitive tests sensitive to frontal lobe dysfunction (Wisconsin Card Sorting Test, Theory of Mind, Tower of London, this latter evidenced a mild impairment in planning performance). In the tests on moral, emotional and social cognition, his patterns of response differed from matched controls and from past reports on criminal psychopaths as, unlike these individuals, KT exhibited normal recognition of fear and a relatively intact knowledge of moral rules but he was impaired in the recognition of anger, embarrassment and conventional social rules. The overall picture of KT suggests that serial killing may be closer to normality than psychopathy defined according to either the DSM IV or the PCL-R, and it would be characterized by a relatively spared moral cognition and selective deficits in social and emotional cognition domains. PMID:23414440

Angrilli, Alessandro; Sartori, Giuseppe; Donzella, Giovanna

2013-01-01

271

Dilution jet mixing program, supplementary report  

NASA Technical Reports Server (NTRS)

The velocity and temperature distributions predicted by a 3-D numerical model and experimental measurements are compared. Empirical correlations for the jet velocity trajectory developed are presented. The measured velocity distributions for all test cases of phase through phase 3 are presented in the form of contour and oblique plots. quantification of the effects of the following on the jet mixing characteristics with a confined crossflow are: (1) orifice geometry momentum flux ratio and density ratio; (2) nonuniform mainstream temperature and velocity profiles upstream of dilution orifices; (3) cold versus hot jet injection; (4) cross-stream flow are a convergence as encountered in practical dilution zone geometries; (5) 2-D slot versus circular orifices; (6) discrete noncirculcer orifices; (7) single-sided versus opposed jets; (8) single row of jets.

Srinivasan, R.; White, C.

1986-01-01

272

Polarized neutron reflectivity of dilute magnetic semiconductors  

Microsoft Academic Search

We report on a polarized neutron reflectivity investigation of the magnetization in Ge-based dilute magnetic semiconductors. We could observe a net magnetization from the splitting of the non-spin flip reflectivity patterns, which measure the magnetic moment parallel and antiparallel to the applied field. This contrast is visible at 50K, at remanence and it is pronounced at higher fields even at

Amitesh Paul; Heiko Braak; Daniel E. Bürgler; Reinert Schreiber; Diana Rata; Peter Grünberg; Claus M. Schneider; Thomas Brückel

2007-01-01

273

Transversal inhomogeneities in dilute vibrofluidized granular fluids  

E-print Network

The spontaneous symmetry breaking taking place in the direction perpendicular to the energy flux in a dilute vibrofluidized granular system is investigated, using both a hydrodynamic description and simulation methods. The latter include molecular dynamics and direct Monte Carlo simulation of the Boltzmann equation. A marginal stability analysis of the hydrodynamic equations, carried out in the WKB approximation, is shown to be in good agreement with the simulation results. The shape of the hydrodynamic profiles beyond the bifurcation is discussed.

J. Javier Brey; M. J. Ruiz-Montero; F. Moreno; R. Garcia-Rojo

2002-01-24

274

Thermoluminescence in ultra-high dilution research  

Microsoft Academic Search

Objective Thermoluminescence of homeopathically prepared ultra-high dilutions of lithium chloride in D2O (10 -30 g cm-3 ; C15 LiCl in D2O) and similarly pre- pared D2O (C15 D2O) was compared in three experiments varying a) time between preparation of substance and time of experimentation, and b) time between irradiation and thermoluminescence recording. Data were also compared with a normal solution

R. van Wijk; S. Bosman; E. P. A. van Wijk

275

Preservative activity in diluted corticosteroid creams.  

PubMed

The preservative efficacy of both 'Betnovate' and 'Synalar' creams diluted 1:1 with 'Unguentum Merck' was investigated. Each formulation was challenged with Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa at an initial inoculum level of approximately 1 X 10(6) viable organisms per gram of cream. All formulations tested were found to be effectively preserved against the organisms used and no viable bacteria were detected 7 days after inoculation. PMID:6208253

Hugo, W B; Denyer, S P; York, H L; Tucker, J D

1984-09-01

276

A dilution refrigerator insert for standard ILL cryostats K. Neumaier  

E-print Network

773 A dilution refrigerator insert for standard ILL cryostats K. Neumaier WMI Garching, F.R.G. A-1.2 K) the sample stick was replaced by a dilution refrigerator insert with a minimum no temperatures, we replaced the sample stick by a dilution refrigerator insert (Fig. 1). The large cooling power

Paris-Sud XI, Université de

277

Dilution and microsegregation in dissimilar metal welds between super austenitic  

E-print Network

Dilution and microsegregation in dissimilar metal welds between super austenitic stainless steel. An important aspect of this processing is the weld metal dilution level, which will control the composition. Since the Fe content of the weld is controlled by dilution, which in turn is controlled by the welding

DuPont, John N.

278

Theory of linear viscoelasticity of semiflexible rods in dilute solution  

E-print Network

Theory of linear viscoelasticity of semiflexible rods in dilute solution V. Shankar, Matteo received 19 June 2002) Synopsis We present a theory of the linear viscoelasticity of dilute solutions semiflexible rods for lengths up to L Lp , and with linear viscoelastic data for dilute solutions of poly

Natelson, Douglas

279

Effective Viscosity Properties of Dilute Suspensions of Arbitrarily Shaped Particles  

E-print Network

Effective Viscosity Properties of Dilute Suspensions of Arbitrarily Shaped Particles Habib Ammari. Mathematics subject classifications (MSC2000): 35B30. Keywords: effective viscosity, dilute suspension and the intrinsic viscosities of the suspension in the dilute limit in terms of the volume fraction occupied

Ammari, Habib

280

Dilution of brackish waters in irrigation networks —An analytic approach  

Microsoft Academic Search

Rational method of improving poor water by the admixture of good-quality water for irrigation purposes is proposed and demonstrated. The principles of the dilution process, carried out in dilution junctions, are explained. Continuity equations for water and for the mass of relevant substances present in the water are derived for a dilution junction. These equations characterize the suitability of the

G. Sinai; E. Koch; M. Farbman

1985-01-01

281

In vitro antibacterial and anti-inflammatory effects of honokiol and magnolol against Propionibacterium sp  

Microsoft Academic Search

Honokiol and magnolol, two major phenolic constituents of Magnolia sp., have been known to exhibit antibacterial activities. However, until now, their antibacterial activity against Propionibacterium sp. has not been reported. To this end, the antibacterial activities of honokiol and magnolol were detected using the disk diffusion method and a two-fold serial dilution assay. Honokiol and magnolol showed strong antibacterial activities

Junho Park; Jongsung Lee; Eunsun Jung; Yumi Park; Kukhyun Kim; Kwangseon Jung; Jieun Kim

2004-01-01

282

Highly Reliable, High-Speed, Unidirectional Serial Data Links  

NASA Technical Reports Server (NTRS)

Highly reliable, high-speed, unidirectional serial data-communication subsystems have been proposed to be installed in an upgrade of the computing systems aboard the space shuttles. The basic design concept of these serial data links is also adaptable to terrestrial use in applications in which there are requirements for highly reliable serial data communications. The hardware and software aspects of the architecture of the data links are dictated largely by a requirement, in the original space-shuttle application, for one computer to monitor the memory transactions and memory contents of other computers in real time with high reliability and without reliance on requests for retransmission. To minimize weight while affording a capability to transfer data at a required rate of 2.56 x 10(exp 8) bits per second, it was decided that the links would be serial ones of the fiber-channel type. [Fiber channel denotes a type of serial computer bus that is used to connect a computer (usually a supercomputer) with a high-speed data storage device. Depending on the specific application, the physical connection between the transmitter and receiver could be made via an optical fiber or a twisted pair of wires.] Heretofore, fiber-channel links have ordinarily been bidirectional and have operated under protocols that provide for receiving stations to detect errors and request retransmission when necessary. In the present case, the time taken by processing to request retransmission would conflict with the requirement for real-time transfer of data. To ensure reliability without retransmission, a link according to the proposal would utilize a modified version of the normal fiberchannel character set in conjunction with forward error correction by means of a Reed-Solomon code (see figure). The Reed-Solomon encoding and decoding and the translations between the normal and modified character sets would be effected by logic circuitry external to the fiber-channel transmitter and receiver, which would be commercial off-the-shelf units. The receiving end of the link could detect and correct errors at a rate as high as 4 million times per second, if necessary. The receiver detects uncorrectable double-byte errors. It has been estimated that uncorrectable-error rate would amount to one failure in about 10(exp 19) characters.

Cole, Robert M.; Bishop, Jamie

2005-01-01

283

Etiology of the Psychopathic Serial Killer: An Analysis of Antisocial Personality Disorder, Psychopathy, and Serial Killer Personality and Crime Scene Characteristics  

Microsoft Academic Search

The purpose of this article is to make the distinction between antisocial personality disorder and psychopathy, discuss possible etiologies of psychopathy, and analyze the crimes, personality characteristics, and historical aspects of psychopathic serial killers. The research indicates that both environmental and biological factors affect the development of psychopathy. Several different serial killers were compared to assess the similarities and differences

Rebecca Taylor LaBrode

2007-01-01

284

Inhibition of oil plume dilution in Langmuir ocean circulation  

NASA Astrophysics Data System (ADS)

Oil spills from deep-water blowouts rise through and interact with the ocean mixed layer and Langmuir turbulence, leading to considerable diversity of oil slick dilution patterns observed on the ocean surface. Certain conditions can drive oil droplet plumes to organize into distinct bands called windrows, inhibiting oil dilution. Observations of blurred or even diffused plumes are also common, but conditions under which these various dilution regimes emerge are not well understood. Here we use large eddy simulations to explain and quantify the dilution patterns and their dependence on relevant physical parameters. Two mechanisms, the downwelling and dilution due to Langmuir cells and the inhibition of dilution due to buoyancy of oil droplets, compete. This competition can be characterized by the ratio of Stokes drift to droplet rise velocity—the drift-to-buoyancy parameter, Db. We find that plume appearance and quantitative measures of relative dilution depend mainly on Db.

Yang, Di; Chamecki, Marcelo; Meneveau, Charles

2014-03-01

285

40 CFR 1065.546 - Validation of minimum dilution ratio for PM batch sampling.  

Code of Federal Regulations, 2011 CFR

...diluted flow), dilution air flow, and dilute exhaust...based on the measured intake air molar flow rate and the...flow rate based on intake air, fuel rate measurements, and...Determine minimum dilution ratio based on tracer gas...

2011-07-01

286

40 CFR 1065.546 - Validation of minimum dilution ratio for PM batch sampling.  

Code of Federal Regulations, 2010 CFR

...diluted flow), dilution air flow, and dilute exhaust...based on the measured intake air molar flow rate and the...flow rate based on intake air, fuel rate measurements, and...Determine minimum dilution ratio based on tracer gas...

2010-07-01

287

Recovering chemical products from dilute fermentation broths  

SciTech Connect

Resurgence of interest in the fermentation of renewable biomass to produce oxychemical feedstocks and specialty chemicals has suggested the corollary need for new energy-efficient processes to recover products from dilute aqueous broths. Of the commercially demonstrated processes, distillation appears most suitable for low boilers, while solvent extraction appears to be the method of choice for high boilers. A number of new approaches such as supercritical extraction, molecular sieve adsorption, and membrane separation hold promise for further development. In any event, the concomitant development of both new fermentation systems and recovery processes appears critical to the growth of a revitalized fermentation industry. 47 references, 14 figures, 5 tables.

Busche, R.M.

1983-01-01

288

Dilution jet mixing program, phase 3  

NASA Technical Reports Server (NTRS)

The main objectives for the NASA Jet Mixing Phase 3 program were: extension of the data base on the mixing of single sided rows of jets in a confined cross flow to discrete slots, including streamlined, bluff, and angled injections; quantification of the effects of geometrical and flow parameters on penetration and mixing of multiple rows of jets into a confined flow; investigation of in-line, staggered, and dissimilar hole configurations; and development of empirical correlations for predicting temperature distributions for discrete slots and multiple rows of dilution holes.

Srinivasan, R.; Coleman, E.; Myers, G.; White, C.

1985-01-01

289

Theory of diluted magnetic semiconductor ferromagnetism  

PubMed

We present a theory of carrier-induced ferromagnetism in diluted magnetic semiconductors ( III1-xMnxV) which allows for arbitrary itinerant-carrier spin polarization and dynamic correlations. Both ingredients are essential in identifying the system's elementary excitations and describing their properties. We find a branch of collective modes, in addition to the spin waves and Stoner continuum which occur in metallic ferromagnets, and predict that the low-temperature spin stiffness is independent of the strength of the exchange coupling between magnetic ions and itinerant carriers. We discuss the temperature dependence of the magnetization and the heat capacity. PMID:10991011

Konig; Lin; MacDonald

2000-06-12

290

A sociological analysis of serial murder: victim and offender characteristics  

E-print Network

of Advisory Committee: Dr. Jane Sell Little work has been devoted to a sociological analysis of serial murder, rather the majority of research conducted on this phenomenon has been psychological in nature. What limited amount of work that has been done... have attracted widespread attention. Explanations include, but are not limited to, such concept. s as a ~~ s}I. aD11L)Laze ~Lure. of xiolrnce. (Hackney 1969; Gastil 1971; Loftin and Hill 1974; Smith and Parker 1980; Messner 1983a; Huff...

Dunlap, Donna Jean

1990-01-01

291

Serially Concatenated Coded Continuous Phase Modulation for Aeronautical Telemetry  

E-print Network

Communication System. 31 3.2 Serially Concatenated Convolutionally Coded CPM with Iterative Turbo Decoding. ................................. 36 3.3 Turbo Product Coded CPM with Iterative Chase Decoding. ....... 37 3.4 Different Styles for Decoding Turbo Product...-Coherent SOQPSK- TG with a Forgetting Factor of 0.9375 and a 2 ? Standard Deviation of Phase Noise. ................................ 68 A.2 BER Performance of Convolutional Code 1 with Non-Coherent PCM/FM with a Forgetting Factor of 0.9375 and a 2 ? Standard...

Porur Damodaran, Kanagaraj

2008-08-26

292

Hi-speed versatile serial crate controller for CAMAC  

SciTech Connect

A serial crate controller, primarily for use in the SLC CAMAC control system, has been designed, and has been in use for about 2 years. The design supports a party line approach, with up to 16 crates on a single twisted pair for data transfers, plus another pair for prompt L response. The bit rate is 5 megabits/s, and complete transaction times of about 10 ..mu..s are achieved for 16-bit data transfers over cables up to 1000 feet long. One of the primary objects of the design was simplicity - there are approximately 60 chips in the two-board unit.

Horelick, D.

1984-10-01

293

Bit-serial RISC processing element for parallel processing  

E-print Network

. busrlc 10. rltem c 09. bustem c 08. imcs 07. imrw 06. dmcs 05. dmrw 04. u c 03. intc 02. ortc 1 01. ortc2 Load PC rom incremen(er load PC rom IR Load IR ron( ins(ruction memory Load M4R lower rom ins(ruc(ion memo Load MAR2 upper from ms...BIT-SERIAL RISC PROCESSING ELEMENT FOR PARALLEL PROCESSING A Thesis by FAISAL A. HAIDAR Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE May...

Haidar, Faisal A

1994-01-01

294

Serial propagation of Creutzfeldt-Jakob disease in guinea pigs.  

PubMed Central

The transmission and serial propagation of Creutzfeldt-Jakob disease from man to guinea pigs are reported. The latency, symptomatology, and morphology of the infection during the first four passages are presented. The incubation period between the first and subsequent passages was halved. One hundred percent take, morbidity, and mortality were achieved in all inoculated animals. All guinea pigs developed a subacute spongiform virus encephalopathy with marked neuronal destruction in the cerebral cortex and subcortical grey structures. The neuronal loss resulted in cerebral atrophy and hydrocephalus ex vacuo. Images PMID:1108016

Manuelidis, E E; Kim, J; Angelo, J N; Manuelidis, L

1976-01-01

295

A Classic Case of Serial Murder Forensics Meets Photonics  

NSDL National Science Digital Library

In this case study, a newly appointed medical examiner uncovers an unusual trend in drowning cases, which she suspects may be the work of a serial murderer. To prove that she is right, she must rely on instrumentation designed and tested by a team of students from the local university. Students read the case, then design and build a device for the detection of blood stains. The case was developed for use in an undergraduate laboratory course sequence in photonics for junior and senior level students. It would be suitable for any undergraduate course in physics, chemistry, or electrical engi eering that covers topics in optics, photonics, or spectroscopy.

Karen Altendorf

2005-01-01

296

Occupational therapy articles in serial publications: an analysis of sources.  

PubMed Central

This study was designed to locate and document serial literature on occupational therapy published since 1900. Emphasis is placed on finding articles on occupational therapy or by occupational therapists from sources other than those normally associated with the professional journals. Multiple sources were used including print indexes, online databases, occupational therapy bibliographies, and tables of contents or yearly indexes. Almost 7,000 articles were identified, not including those published in foreign journals. Occupational therapy publications have increased steadily since 1900, with the most rapid increase during the 1970s and 1980s when five new occupational therapy journals were initiated. Suggestions for formulating search strategies are included. PMID:3285932

Reed, K L

1988-01-01

297

Stoichiometric controls of mercury dilution by growth  

PubMed Central

Rapid growth could significantly reduce methylmercury (MeHg) concentrations in aquatic organisms by causing a greater than proportional gain in biomass relative to MeHg (somatic growth dilution). We hypothesized that rapid growth from the consumption of high-quality algae, defined by algal nutrient stoichiometry, reduces MeHg concentrations in zooplankton, a major source of MeHg for lake fish. Using a MeHg radiotracer, we measured changes in MeHg concentrations, growth and ingestion rates in juvenile Daphnia pulex fed either high (C:P = 139) or low-quality (C:P = 1317) algae (Ankistrodesmus falcatus) for 5 d. We estimated Daphnia steady-state MeHg concentrations, using a biokinetic model parameterized with experimental rates. Daphnia MeHg assimilation efficiencies (?95%) and release rates (0.04 d?1) were unaffected by algal nutrient quality. However, Daphnia growth rate was 3.5 times greater when fed high-quality algae, resulting in pronounced somatic growth dilution. Steady-state MeHg concentrations in Daphnia that consumed high-quality algae were one-third those of Daphnia that consumed low-quality algae due to higher growth and slightly lower ingestion rates. Our findings show that rapid growth from high-quality food consumption can significantly reduce the accumulation and trophic transfer of MeHg in freshwater food webs. PMID:17456601

Karimi, Roxanne; Chen, Celia Y.; Pickhardt, Paul C.; Fisher, Nicholas S.; Folt, Carol L.

2007-01-01

298

Stoichiometric controls of mercury dilution by growth.  

PubMed

Rapid growth could significantly reduce methylmercury (MeHg) concentrations in aquatic organisms by causing a greater than proportional gain in biomass relative to MeHg (somatic growth dilution). We hypothesized that rapid growth from the consumption of high-quality algae, defined by algal nutrient stoichiometry, reduces MeHg concentrations in zooplankton, a major source of MeHg for lake fish. Using a MeHg radiotracer, we measured changes in MeHg concentrations, growth and ingestion rates in juvenile Daphnia pulex fed either high (C:P = 139) or low-quality (C:P = 1317) algae (Ankistrodesmus falcatus) for 5 d. We estimated Daphnia steady-state MeHg concentrations, using a biokinetic model parameterized with experimental rates. Daphnia MeHg assimilation efficiencies (approximately 95%) and release rates (0.04 d(-1)) were unaffected by algal nutrient quality. However, Daphnia growth rate was 3.5 times greater when fed high-quality algae, resulting in pronounced somatic growth dilution. Steady-state MeHg concentrations in Daphnia that consumed high-quality algae were one-third those of Daphnia that consumed low-quality algae due to higher growth and slightly lower ingestion rates. Our findings show that rapid growth from high-quality food consumption can significantly reduce the accumulation and trophic transfer of MeHg in freshwater food webs. PMID:17456601

Karimi, Roxanne; Chen, Celia Y; Pickhardt, Paul C; Fisher, Nicholas S; Folt, Carol L

2007-05-01

299

The Statistical Mechanics of Dilute, Disordered Systems  

NASA Astrophysics Data System (ADS)

Available from UMI in association with The British Library. Requires signed TDF. A graph partitioning problem with variable inter -partition costs is studied by exploiting its mapping on to the Ashkin-Teller spin glass. The cavity method is used to derive the TAP equations and free energy for both extensively connected and dilute systems. Unlike Ising and Potts spin glasses, the self-consistent equation for the distribution of effective fields does not have a solution solely made up of delta functions. Numerical integration is used to find the stable solution, from which the ground state energy is calculated. Simulated annealing is used to test the results. The retrieving activity distribution for networks of boolean functions trained as associative memories for optimal capacity is derived. For infinite networks, outputs are shown to be frozen, in contrast to dilute asymmetric networks trained with the Hebb rule. For finite networks, a steady leaking to the non-retrieving attractor is demonstrated. Simulations of quenched networks are reported which show a departure from this picture: some configurations remain frozen for all time, while others follow cycles of small periods. An estimate of the critical capacity from the simulations is found to be in broad agreement with recent analytical results. The existing theory is extended to include noise on recall, and the behaviour is found to be robust to noise up to order 1/c^2 for networks with connectivity c.

Blackburn, Roger Michael

300

ANALYSIS OF BORON DILUTION TRANSIENTS IN PWRS.  

SciTech Connect

A study has been carried out with PARCS/RELAP5 to understand the consequences of hypothetical boron dilution events in pressurized water reactors. The scenarios of concern start with a small-break loss-of-coolant accident. If the event leads to boiling in the core and then the loss of natural circulation, a boron-free condensate can accumulate in the cold leg. The dilution event happens when natural circulation is re-established or a reactor coolant pump (RCP) is restarted in violation of operating procedures. This event is of particular concern in B&W reactors with a lowered-loop design and is a Generic Safety Issue for the U.S. Nuclear Regulatory Commission. The results of calculations with the reestablishment of natural circulation show that there is no unacceptable fuel damage. This is determined by calculating the maximum fuel pellet enthalpy, based on the three-dimensional model, and comparing it with the criterion for damage. The calculation is based on a model of a B&W reactor at beginning of the fuel cycle. If an RCP is restarted, unacceptable fuel damage may be possible in plants with sufficiently large volumes of boron-free condensate in the cold leg.

DIAMOND,D.J.BROMLEY,B.P.ARONSON,A.L.

2004-02-04

301

EDITORIAL: Focus on Dilute Magnetic Semiconductors FOCUS ON DILUTE MAGNETIC SEMICONDUCTORS  

Microsoft Academic Search

This focus issue of New Journal of Physics is devoted to the materials science of dilute magnetic semiconductors (DMS). A DMS is traditionally defined as a diamagnetic semiconductor doped with a few to several atomic per cent of some transition metal with unpaired d electrons. Several kinds of dopant dopant interactions can in principle couple the dopant spins leading to

Scott A. Chambers; Bryan Gallagher

2008-01-01

302

Women’s Role in Serial Killing Teams: Reconstructing a Radical Feminist Perspective  

Microsoft Academic Search

This article examines women’s roles in serial killing teams and reconsiders the traditional applications of radical feminist\\u000a research on serial killers. These applications limit the utility of radical feminist theory for understanding female serial\\u000a killers who kill in teams. An analysis of patriarchal power relations, which emphasizes the constitutive element of radical\\u000a feminist theory, provides a useful framework to achieve

Jennie Thompson; Suzanne Ricard

2009-01-01

303

Identifying Cell Class Specific Losses from Serially Generated Electroretinogram Components  

PubMed Central

Purpose. Processing of information through the cellular layers of the retina occurs in a serial manner. In the electroretinogram (ERG), this complicates interpretation of inner retinal changes as dysfunction may arise from “upstream” neurons or may indicate a direct loss to that neural generator. We propose an approach that addresses this issue by defining ERG gain relationships. Methods. Regression analyses between two serial ERG parameters in a control cohort of rats are used to define gain relationships. These gains are then applied to two models of retinal disease. Results. The PIIIamp to PIIamp gain is unity whereas the PIIamp to pSTRamp and PIIamp to nSTRamp gains are greater than unity, indicating “amplification” (P < 0.05). Timing relationships show amplification between PIIIit to PIIit and compression for PIIit to pSTRit and PIIit to nSTRit, (P < 0.05). Application of these gains to ?-3-deficiency indicates that all timing changes are downstream of photoreceptor changes, but a direct pSTR amplitude loss occurs (P < 0.05). Application to diabetes indicates widespread inner retinal dysfunction which cannot be attributed to outer retinal changes (P < 0.05). Conclusions. This simple approach aids in the interpretation of inner retinal ERG changes by taking into account gain characteristics found between successive ERG components of normal animals. PMID:24089688

Nguyen, Christine T. O.; Vingrys, Algis J.; Wong, Vickie H. Y.; Bui, Bang V.

2013-01-01

304

The serial nature of the masked onset priming effect revisited.  

PubMed

Reading aloud is faster when target words/nonwords are preceded by masked prime words/nonwords that share their first sound with the target (e.g., save-SINK) compared to when primes and targets are unrelated to each other (e.g., farm-SINK). This empirical phenomenon is the masked onset priming effect (MOPE) and is known to be due to serial left-to-right processing of the prime by a sublexical reading mechanism. However, the literature in this domain lacks a critical experiment. It is possible that when primes are real words their orthographic/phonological representations are activated in parallel and holistically during prime presentation, so any phoneme overlap between primes and targets (and not just initial-phoneme overlap) could facilitate target reading aloud. This is the prediction made by the only computational models of reading aloud that are able to simulate the MOPE, namely the DRC1.2.1, CDP+, and CDP++ models. We tested this prediction in the present study and found that initial-phoneme overlap (blip-BEST), but not end-phoneme overlap (flat-BEST), facilitated target reading aloud compared to no phoneme overlap (junk-BEST). These results provide support for a reading mechanism that operates serially and from left to right, yet are inconsistent with all existing computational models of single-word reading aloud. PMID:24853396

Mousikou, Petroula; Coltheart, Max

2014-01-01

305

Serial crystallography on in vivo grown microcrystals using synchrotron radiation  

PubMed Central

Crystal structure determinations of biological macromolecules are limited by the availability of sufficiently sized crystals and by the fact that crystal quality deteriorates during data collection owing to radiation damage. Exploiting a micrometre-sized X-ray beam, high-precision diffractometry and shutterless data acquisition with a pixel-array detector, a strategy for collecting data from many micrometre-sized crystals presented to an X-ray beam in a vitrified suspension is demonstrated. By combining diffraction data from 80 Trypanosoma brucei procathepsin B crystals with an average volume of 9?µm3, a complete data set to 3.0?Å resolution has been assembled. The data allowed the refinement of a structural model that is consistent with that previously obtained using free-electron laser radiation, providing mutual validation. Further improvements of the serial synchrotron crystallography technique and its combination with serial femtosecond crystallography are discussed that may allow the determination of high-resolution structures of micrometre-sized crystals. PMID:25075324

Gati, Cornelius; Bourenkov, Gleb; Klinge, Marco; Rehders, Dirk; Stellato, Francesco; Oberthür, Dominik; Yefanov, Oleksandr; Sommer, Benjamin P.; Mogk, Stefan; Duszenko, Michael; Betzel, Christian; Schneider, Thomas R.; Chapman, Henry N.; Redecke, Lars

2014-01-01

306

Auditory word serial recall benefits from orthographic dissimilarity.  

PubMed

The influence of orthographic knowledge has been consistently observed in dissimilarity speech recognition and metaphonological tasks. The present study provides data suggesting that such influence also pervades other cognitive domains phonological related to language abilities, such as verbal working memory. Using serial similarity effect recall of auditory seven-word lists, we observed that inter-item orthographic dissimilarity assists verbal working memory by reducing or even avoiding verbal serial recall the detrimental effect of phonological similarity. However, this orthographic modulation of the phonological similarity effect only occurred at positions four to six of the word list. Performance at position seven benefited from a recency effect that may be assumed to result from a more surface-level (acoustic-phonetic) representation, while better performance at positions one to three is attributable to primacy effects, and can be accounted for in terms of consolidation through recapitulation. The beneficial influence of orthographic knowledge may, therefore, only be apparent when the item stored in short-term memory takes the form of an abstract but unconsolidated phonological representation. PMID:21033650

Pattamadilok, Chotiga; Lafontaine, Hélène; Morais, José; Kolinsky, Régine

2010-01-01

307

Serial manipulator functional calibration for in vitro biomechanical testing.  

PubMed

Serial manipulators are often used in biomechanical testing of human joints because they are precise, repeatable instruments that can create interesting loading scenarios. Unfortunately, commercial serial manipulators often do not have acceptable global positional accuracy due to manufacturing tolerances, assembly errors, and other mechanical imperfections. Numerous calibration methods have been reported which calibrate geometric and non-geometric parameters to reduce static position errors under constant loading conditions. However, the manipulator's global accuracy during continuous motion with time-varying external loading conditions is often not addressed but is necessary for joint biomechanical testing. Using the Mitsubishi PA10-6CE as a case study, a novel functional calibration procedure was developed that performs both static and dynamic calibration. The calibration uses optimization techniques to populate a 34-parameter model that accounts for the robot's geometric and non-geometric parameters and significantly reduces the mean/peak static and dynamic position errors to 0.368/0.67 mm and 0.353/0.81 mm, respectively, while externally loaded. PMID:24262850

Hill, Ira; Banks, Scott

2014-01-01

308

Molluscan engrailed expression, serial organization, and shell evolution.  

PubMed

Whether the serial features found in some molluscs are ancestral or derived is considered controversial. Here, in situ hybridization and antibody studies show iterated engrailed-gene expression in transverse rows of ectodermal cells bounding plate field development and spicule formation in the chiton, Lepidochitona cavema, as well as in cells surrounding the valves and in the early development of the shell hinge in the clam, Transennella tantilla. Ectodermal expression of engrailed is associated with skeletogenesis across a range of bilaterian phyla, suggesting a single evolutionary origin of invertebrate skeletons. The shared ancestry of bilaterian-invertebrate skeletons may help explain the sudden appearance of shelly fossils in the Cambrian. Our interpretation departs from the consideration of canonical metameres or segments as units of evolutionary analysis. In this interpretation, the shared ancestry of engrailed-gene function in the terminal/posterior addition of serially repeated elements during development explains the iterative expression of engrailed genes in a range of metazoan body plans. PMID:11256378

Jacobs, D K; Wray, C G; Wedeen, C J; Kostriken, R; DeSalle, R; Staton, J L; Gates, R D; Lindberg, D R

2000-01-01

309

Serial agonistic attacks by greylag goose families, Anser anser, against the same opponent  

PubMed Central

It is known from primates that alliance partners may support each other’s interests in competition with others, for example, through repeated agonistic attacks against a particular individual. We examined serial aggressive interactions between greylag goose families and other flock members. We found that repeated attacks towards the same individual were common and that up to five serial attacks by family members followed an initial attack. Family size did not affect the frequency of such serial attacks. Juvenile geese evidently benefited most from active social support through serial attacks. About 60% of the juveniles’ lost primary interactions were subsequently reversed by another family member. This may be one of the reasons why juveniles rank higher in the social hierarchy than would be expected from their age and size alone. Losses in serial attacks predominantly occurred against other, presumably higher-ranking, family geese and ganders. We propose three major functions/consequences of serial attacks. Analogous to primates, serial attacks in greylag geese may serve to reinforce a losing experience of an opponent defeated in a preceding attack. On the side of the winning family, serial attacks may reinforce the experience of winning. Both winning and losing experiences are linked with physiological consequences in higher vertebrates, affecting the future social performance of winners or losers. Finally, serial attacks may signal the agonistic potential of a family to other flock members. This is supported by heart rate data, which indicate that greylags are competent to interpret third-party relationships. PMID:21984838

Scheiber, Isabella B.R.; Kotrschal, Kurt; Weiß, Brigitte M.

2011-01-01

310

A computerized serials record system for the Texas A&M University Library  

E-print Network

VI PROPOSED SYSTEM FLOW CHARTS 17 38 53 68 83 107 LIST OF FIGURES 1 Kardex Arrival Card . 2 Kardex Order Card . 3 Order' Subfile Card 4L Serials Holdings Card . 4B Serials Holdings Card ? Back 5 Serials Iacks Card 6A Bindery Card 6B... Libraries, " (Paper presented at Purdue-SLA Conference on Automation in the Library, Lafayette, Indiana, October 2, 1964) ~ I' H. Pizer, D. R. Franz, E. Brodman, ?Mechanization of Library Procedures in the Medium-sized Medical Library: 1 ~ The Serial...

Stewart, Bruce Warren

1965-01-01

311

Dilution of boar ejaculates with BTS containing HEPES in place of bicarbonate immediately after ejaculation can reduce the increased inducibility of the acrosome reaction by treatment with calcium and calcium ionophore A23187, which is potentially associated with boar subfertility.  

PubMed

The present study investigated whether substitution of HEPES for bicarbonate in BTS (BTS-H) used to dilute boar ejaculates immediately after ejaculation could reduce the increased inducibility of the acrosome reaction by calcium and calcium ionophore A23187. When an ejaculate was split, diluted 5-fold with regular BTS (BTS-B) and BTS-H and stored at 17 C for 12 h or 60 h, the extender or storage time had no significant influence on sperm motility or viability measured by the eosin-nigrosin method. When spermatozoa diluted serially with BTS-B and stored (36 h) were stimulated with Ca2+ (3 mM) and A23187 (0.3 microM), the proportion of spermatozoa that underwent the acrosome reaction (% acrosome reactions) significantly increased as the magnifications of dilution increased (bicarbonate content almost unchanged by dilution). By contrast, the % acrosome reactions in spermatozoa similarly diluted and stored with BTS-H decreased with the increasing magnifications of dilution (bicarbonate decreased). Sperm motility immediately after the end of incubation without A23178 tended to be lower for BTS-H than BTS-B, and the ejaculates for BTS-H had a tendency to have a lower total protein in seminal plasma than those for BTS-B. These results implied that the samples for BTS-H could be used as a model for ejaculates possibly collected during summer and showing subfertility. When an ejaculate was split, diluted serially with BTS-B and BTS-H and stored, viability measured by staining with propidium iodide was extremely similar between the 2 extenders and among the different dilution magnifications, regardless of whether spermatozoa were washed (stored for 36-66 h) or not (stored for 66-72 h). These results suggest that boar ejaculate can be stored with BTS-H at least according to the results for sperm motility and viability and that hypersensitivity of spermatozoa to Ca2+ and A23187 potentially associated with boar subfertility could be lessened by diluting ejaculates with BTS-H. PMID:20197642

Murase, Tetsuma; Imaeda, Noriaki; Yamada, Hiroto; Takasu, Masaki; Taguchi, Kazuo; Katoh, Tsutomu

2010-06-01

312

Characterization of the Dilute Ising Antiferromagnet  

SciTech Connect

A spin glass is a magnetic ground state in which ferromagnetic and antiferromagnetic exchange interactions compete, thereby creating frustration and a multidegenerate state with no long range order. An Ising system is a system where the spins are constrained to lie parallel or antiparallel to a primary axis. There has been much theoretical interest in the past ten years in the effects of applying a magnetic field transverse to the primary axis in an Ising spin glass at low temperatures and thus study phase transitions at the T=0 limit. The focus of this study is to search for and characterize a new Ising spin glass system. This is accomplished by site diluting yttrium for terbium in the crystalline material TbNi{sub 2}Ge{sub 2}. The first part of this work gives a brief overview of the physics of rare earth magnetism and an overview of experimental characteristics of spin glasses. This is followed by the methodology used to manufacture the large single crystals used in this study, as well as the measurement techniques used. Next, a summary of the results of magnetic measurements on across the dilution series from pure terbium to pure yttrium is presented. This is followed by detailed measurements on particular dilutions which demonstrate spin glass behavior. Pure TbNi{sub 2}Ge{sub 2} is an Ising antiferromagnet with a several distinct metamagnetic states below 17 K. As the terbium is alloyed with yttrium, these magnetic states are weakened in a consistent manner, as is seen in measurements of the transition temperatures and analysis of Curie-Weiss behavior at high temperature. At low concentrations of terbium, below 35%, long range order is no longer present and a spin-glass-like state emerges. This state is studied through various measurements, dc and ac susceptibility, resistivity, and specific heat. This magnetic behavior was then compared to that of other well characterized spin glasses. It is concluded that there is a region of concentration s for which a spin glass state is formed with the best spin glasses existing between the concentration of 25% and 30%.

Wiener, T.

2000-09-12

313

Dilute acid/metal salt hydrolysis of lignocellulosics  

DOEpatents

A modified dilute acid method of hydrolyzing the cellulose and hemicellulose in lignocellulosic material under conditions to obtain higher overall fermentable sugar yields than is obtainable using dilute acid alone, comprising: impregnating a lignocellulosic feedstock with a mixture of an amount of aqueous solution of a dilute acid catalyst and a metal salt catalyst sufficient to provide higher overall fermentable sugar yields than is obtainable when hydrolyzing with dilute acid alone; loading the impregnated lignocellulosic feedstock into a reactor and heating for a sufficient period of time to hydrolyze substantially all of the hemicellulose and greater than 45% of the cellulose to water soluble sugars; and recovering the water soluble sugars.

Nguyen, Quang A. (Golden, CO); Tucker, Melvin P. (Lakewood, CO)

2002-01-01

314

21 CFR 866.2500 - Microtiter diluting and dispensing device.  

Code of Federal Regulations, 2011 CFR

...ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES IMMUNOLOGY AND MICROBIOLOGY DEVICES Microbiology Devices § 866.2500 Microtiter diluting and dispensing device. (a) Identification....

2011-04-01

315

21 CFR 866.2500 - Microtiter diluting and dispensing device.  

Code of Federal Regulations, 2012 CFR

...ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES IMMUNOLOGY AND MICROBIOLOGY DEVICES Microbiology Devices § 866.2500 Microtiter diluting and dispensing device. (a) Identification....

2012-04-01

316

21 CFR 866.2500 - Microtiter diluting and dispensing device.  

Code of Federal Regulations, 2013 CFR

...ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES IMMUNOLOGY AND MICROBIOLOGY DEVICES Microbiology Devices § 866.2500 Microtiter diluting and dispensing device. (a) Identification....

2013-04-01

317

21 CFR 866.2500 - Microtiter diluting and dispensing device.  

Code of Federal Regulations, 2014 CFR

...ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES IMMUNOLOGY AND MICROBIOLOGY DEVICES Microbiology Devices § 866.2500 Microtiter diluting and dispensing device. (a) Identification....

2014-04-01

318

Are Room Temperature Ionic Liquids Dilute Electrolytes?  

E-print Network

An important question in understanding the structure of ionic liquids is whether ions are truly "free" and mobile which would correspond to a concentrated ionic melt, or are rather "bound" in ion pairs, that is a liquid of ion pairs with a small concentration of free ions. Recent surface force balance experiments from different groups have given conflicting answers to this question. We propose a simple model for the thermodynamics and kinetics of ion pairing in ionic liquids. Our model takes into account screened ion-ion, dipole-dipole and dipole-ion interactions in the mean field limit. The results of this model suggest that almost two thirds of the ions are free at any instant, and ion pairs have a short lifetime comparable to the characteristic timescale for diffusion. These results suggest that there is no particular thermodynamic or kinetic preference for ions residing in pairs. We therefore conclude that ionic liquids are concentrated, rather than dilute, electrolytes.

Lee, Alpha A; Perkin, Susan; Goriely, Alain

2014-01-01

319

Are Room Temperature Ionic Liquids Dilute Electrolytes?  

E-print Network

An important question in understanding the structure of ionic liquids is whether ions are truly "free" and mobile which would correspond to a concentrated ionic melt, or are rather "bound" in ion pairs, that is a liquid of ion pairs with a small concentration of free ions. Recent surface force balance experiments from different groups have given conflicting answers to this question. We propose a simple model for the thermodynamics and kinetics of ion pairing in ionic liquids. Our model takes into account screened ion-ion, dipole-dipole and dipole-ion interactions in the mean field limit. The results of this model suggest that almost two thirds of the ions are free at any instant, and ion pairs have a short lifetime comparable to the characteristic timescale for diffusion. These results suggest that there is no particular thermodynamic or kinetic preference for ions residing in pairs. We therefore conclude that ionic liquids are concentrated, rather than dilute, electrolytes.

Alpha A Lee; Dominic Vella; Susan Perkin; Alain Goriely

2014-12-26

320

Shearing instability of a dilute granular mixture.  

PubMed

The shearing instability of a dilute granular mixture composed of smooth inelastic hard spheres or disks is investigated. By using the Navier-Stokes hydrodynamic equations, it is shown that the scaled transversal velocity mode exhibits a divergent behavior, similarly to what happens in one-component systems. The theoretical prediction for the critical size is compared with direct Monte Carlo simulations of the Boltzmann equations describing the system, and a good agreement is found. The total energy fluctuations in the vicinity of the transition are shown to scale with the second moment of the distribution. The scaling distribution function is the same as found in other equilibrium and nonequilibrium phase transitions, suggesting the existence of some kind of universality. PMID:23496508

Brey, J Javier; Ruiz-Montero, M J

2013-02-01

321

Shock waves in a dilute granular gas  

NASA Astrophysics Data System (ADS)

We study the evolution of shock waves in a dilute granular gas which is modelled using three variants of hydrodynamic equations: Euler, 10-moment and 14-moment models. The one-dimensional shock-wave problem is formulated and the resulting equations are solved numerically using a relaxation-type scheme. Focusing on the specific case of blast waves, the results on the density, the granular temperature, the skew temperature, the heat flux and the fourth moment are compared among three models. We find that the shock profiles are smoother for the 14-moment model compared to those predicted by the standard Euler equations. A shock-splitting phenomenon is observed in the skew granular temperature profiles for a blast wave.

Reddy, M. H. Lakshminarayana; Ansumali, Santosh; Alam, Meheboob

2014-12-01

322

The magnetic behavior of diluted magnetic semiconductors  

NASA Astrophysics Data System (ADS)

The magnetic properties of Diluted Magnetic Semiconductors (DMS) are discussed. With respect to Mn containing DMS, focus is on the d-d exchange (J) between Mn ions, in particular the strength of J as well as the relevance of long range interactions. A family of DMS containing Fe instead of Mn is introduced and physical effects arising from Fe levels located above the valence bands, which are not populated in the Mn case, are observed. The influence of this on the magnetic properties is discussed. The IV-VI group DMS is introduced. In comparison with II-VI and II-V materials, the carrier concentration in these systems is very high, leading in some cases to ferromagnetic RKKY interactions. The ferromagnetic interactions in Pb(1-x-y)Sn(y)Mn(x)Te and Sn(1-2)Mn(x)Te strongly depend on the carrier density. This phenomena (carrier induced ferromagnetism) is introduced and recent developments are reported.

Swagten, Henricus Johannes Maria

323

Dilute Oxygen Combustion Phase 3 Final Report  

SciTech Connect

Dilute Oxygen Combustion (DOC) burners have been successfully installed and operated in the reheat furnace at Auburn Steel Co., Inc., Auburn, NY, under Phase 3 of the Dilute Oxygen Combustion project. Two new preheat zones were created employing a total of eight 6.5 MMBtu/hr capacity burners. The preheat zones provide a 30 percent increase in maximum furnace production rate, from 75 tph to 100 tph. The fuel rate is essentially unchanged, with the fuel savings expected from oxy-fuel combustion being offset by higher flue gas temperatures. When allowance is made for the high nitrogen level and high gas phase temperature in the furnace, measured NOx emissions are in line with laboratory data on DOC burners developed in Phase 1 of the project. Burner performance has been good and there have been no operating or maintenance problems. The DOC system continues to be used as part of Auburn Steel?s standard reheat furnace practice. High gas phase temperature is a result of the high firing density needed to achieve high production rates, and little opportunity exists for improvement in that area. However, fuel and NOx performance can be improved by further conversion of furnace zones to DOC burners, which will lower furnace nitrogen levels. Major obstacles are cost and concern about increased formation of oxide scale on the steel. Oxide scale formation may be enhanced by exposure of the steel to higher concentrations of oxidizing gas components (primarily products of combustion) in the higher temperature zones of the furnace. Phase 4 of the DOC project will examine the rate of oxide scale formation in these higher temperature zones and develop countermeasures that will allow DOC burners to be used successfully in these furnace zones.

Riley, M.F.; Ryan, H.M.

2000-05-31

324

Dilute Oxygen Combustion - Phase 3 Report  

SciTech Connect

Dilute Oxygen Combustion (DOC) burners have been successfully installed and operated in the reheat furnace at Auburn Steel Co., Inc., Auburn, NY, under Phase 3 of the Dilute Oxygen Combustion project. Two new preheat zones were created employing a total of eight 6.5 MMBtu/hr capacity burners. The preheat zones provide a 30 percent increase in maximum furnace production rate, from 75 tph to 100 tph. The fuel rate is essentially unchanged, with the fuel savings expected from oxy-fuel combustion being offset by higher flue gas temperatures. When allowance is made for the high nitrogen level and high gas phase temperature in the furnace, measured NOx emissions are in line with laboratory data on DOC burners developed in Phase 1 of the project. Burner performance has been good, and there have been no operating or maintenance problems. The DOC system continues to be used as part of Auburn Steel's standard reheat furnace practice. High gas phase temperature is a result of the high firing density needed to achieve high production rates, and little opportunity exists for improvement in that area. However, fuel and NOx performance can be improved by further conversion on furnace zones to DOC burners, which will lower furnace nitrogen levels. Major obstacles are cost and concern about increased formation of oxide scale on the steel. Oxide scale formation may be enhanced by exposure of the steel to higher concentrations of oxidizing gas components (primarily products of combustion) in the higher temperature zones of the furnace. Phase 4 of the DOC project will examine the rate of oxide scale formation in these higher temperature zones and develop countermeasures that will allow DOC burners to be used successfully in these furnace zones.

Riley, Michael F.

2000-05-31

325

Optimal operation of turbo blowers serially connected using inlet vanes  

NASA Astrophysics Data System (ADS)

Optimal operation of the turbo blowers having an inlet vane has been studied to understand the blowers' operating performance. To analyze three-dimensional flow field in the turbo blowers serially connected, general analysis code, CFX, is introduced in the present work. SST turbulence model is employed to estimate the eddy viscosity. Throughout the numerical analysis, it is found that the flow rates of the turbo blowers can be controlled at the vane angle between 90 (full open condition) degrees and 60 degrees effectively, because pressure loss rapidly increases below 60 degree of a vane angle. Efficiency also has almost the same values from 90 degrees to 60 degrees of a vane angle. It is noted that the distorted inlet velocity generated in the small vane angle makes performance deterioration of the turbo blowers due to the local leading edge separation and the following non-uniform blade loading.

Jang, Choon-Man

2011-03-01

326

Closed-Loop Analysis of Soft Decisions for Serial Links  

NASA Technical Reports Server (NTRS)

We describe the benefit of using closed-loop measurements for a radio receiver paired with a counterpart transmitter. We show that real-time analysis of the soft decision output of a receiver can provide rich and relevant insight far beyond the traditional hard-decision bit error rate (BER) test statistic. We describe a Soft Decision Analyzer (SDA) implementation for closed-loop measurements on single- or dual- (orthogonal) channel serial data communication links. The analyzer has been used to identify, quantify, and prioritize contributors to implementation loss in live-time during the development of software defined radios. This test technique gains importance as modern receivers are providing soft decision symbol synchronization as radio links are challenged to push more data and more protocol overhead through noisier channels, and software-defined radios (SDRs) use error-correction codes that approach Shannon's theoretical limit of performance.

Lansdowne, Chatwin A.; Steele, Glen F.; Zucha, Joan P.; Schlesinger, Adam M.

2013-01-01

327

Liquid sample delivery techniques for serial femtosecond crystallography.  

PubMed

X-ray free-electron lasers overcome the problem of radiation damage in protein crystallography and allow structure determination from micro- and nanocrystals at room temperature. To ensure that consecutive X-ray pulses do not probe previously exposed crystals, the sample needs to be replaced with the X-ray repetition rate, which ranges from 120 Hz at warm linac-based free-electron lasers to 1 MHz at superconducting linacs. Liquid injectors are therefore an essential part of a serial femtosecond crystallography experiment at an X-ray free-electron laser. Here, we compare different techniques of injecting microcrystals in solution into the pulsed X-ray beam in vacuum. Sample waste due to mismatch of the liquid flow rate to the X-ray repetition rate can be addressed through various techniques. PMID:24914163

Weierstall, Uwe

2014-07-17

328

An improved integration method in serial femtosecond crystallography.  

PubMed

Recent experiments in serial femtosecond crystallography (SFX) have demonstrated the feasibility of obtaining structural information from nanoscale crystals using X-ray free-electron lasers (XFELs). However, millions of crystals are required to determine one reliable structure. Here, an improved integration algorithm for SFX data processing is reported. By evaluating the dimensions of each crystal and correcting for the geometric factors of single patterns, the effective diffraction intensities, as opposed to the directly measured single-shot pattern diffraction intensities, can be merged to acquire more accurate integrated intensities which can be used for structure determination. This improvement enhances the quality of electron-density maps and decreases the number of diffraction patterns that are needed to solve the crystal structure in SFX experiments. PMID:24816090

Qu, Kun; Zhou, Liang; Dong, Yu-Hui

2014-05-01

329

Bit-Serial Adder Based on Quantum Dots  

NASA Technical Reports Server (NTRS)

A proposed integrated circuit based on quantum-dot cellular automata (QCA) would function as a bit-serial adder. This circuit would serve as a prototype building block for demonstrating the feasibility of quantum-dots computing and for the further development of increasingly complex and increasingly capable quantum-dots computing circuits. QCA-based bit-serial adders would be especially useful in that they would enable the development of highly parallel and systolic processors for implementing fast Fourier, cosine, Hartley, and wavelet transforms. The proposed circuit would complement the QCA-based circuits described in "Implementing Permutation Matrices by Use of Quantum Dots" (NPO-20801), NASA Tech Briefs, Vol. 25, No. 10 (October 2001), page 42 and "Compact Interconnection Networks Based on Quantum Dots" (NPO-20855), which appears elsewhere in this issue. Those articles described the limitations of very-large-scale-integrated (VLSI) circuitry and the major potential advantage afforded by QCA. To recapitulate: In a VLSI circuit, signal paths that are required not to interact with each other must not cross in the same plane. In contrast, for reasons too complex to describe in the limited space available for this article, suitably designed and operated QCA-based signal paths that are required not to interact with each other can nevertheless be allowed to cross each other in the same plane without adverse effect. In principle, this characteristic could be exploited to design compact, coplanar, simple (relative to VLSI) QCA-based networks to implement complex, advanced interconnection schemes. To enable a meaningful description of the proposed bit-serial adder, it is necessary to further recapitulate the description of a quantum-dot cellular automation from the first-mentioned prior article: A quantum-dot cellular automaton contains four quantum dots positioned at the corners of a square cell. The cell contains two extra mobile electrons that can tunnel (in the quantum-mechanical sense) between neighboring dots within the cell. The Coulomb repulsion between the two electrons tends to make them occupy antipodal dots in the cell. For an isolated cell, there are two energetically equivalent arrangements (denoted polarization states) of the extra electrons. The cell polarization is used to encode binary information. Because the polarization of a nonisolated cell depends on Coulomb-repulsion interactions with neighboring cells, universal logic gates and binary wires could be constructed, in principle, by arraying QCA of suitable design in suitable patterns. Again, for reasons too complex to describe here, in order to ensure accuracy and timeliness of the output of a QCA array, it is necessary to resort to an adiabatic switching scheme in which the QCA array is divided into subarrays, each controlled by a different phase of a multiphase clock signal. In this scheme, each subarray is given time to perform its computation, then its state is frozen by raising its inter-dot potential barriers and its output is fed as the input to the successor subarray. The successor subarray is kept in an unpolarized state so it does not influence the calculation of preceding subarray. Such a clocking scheme is consistent with pipeline computation in the sense that each different subarray can perform a different part of an overall computation. In other words, QCA arrays are inherently suitable for pipeline and, moreover, systolic computations. This sequential or pipeline aspect of QCA would be utilized in the proposed bit-serial adders.

Fijany, Amir; Toomarian, Nikzad; Modarress, Katayoon; Spotnitz, Mathew

2003-01-01

330

The evolution of photosynthesis in chromist algae through serial endosymbioses  

PubMed Central

Chromist algae include diverse photosynthetic organisms of great ecological and social importance. Despite vigorous research efforts, a clear understanding of how various chromists acquired photosynthetic organelles has been complicated by conflicting phylogenetic results, along with an undetermined number and pattern of endosymbioses, and the horizontal movement of genes that accompany them. We apply novel statistical approaches to assess impacts of endosymbiotic gene transfer on three principal chromist groups at the heart of long-standing controversies. Our results provide robust support for acquisitions of photosynthesis through serial endosymbioses, beginning with the adoption of a red alga by cryptophytes, then a cryptophyte by the ancestor of ochrophytes, and finally an ochrophyte by the ancestor of haptophytes. Resolution of how chromist algae are related through endosymbioses provides a framework for unravelling the further reticulate history of red algal-derived plastids, and for clarifying evolutionary processes that gave rise to eukaryotic photosynthetic diversity. PMID:25493338

Stiller, John W.; Schreiber, John; Yue, Jipei; Guo, Hui; Ding, Qin; Huang, Jinling

2014-01-01

331

Closed-Loop Analysis of Soft Decisions for Serial Links  

NASA Technical Reports Server (NTRS)

Modern receivers are providing soft decision symbol synchronization as radio links are challenged to push more data and more overhead through noisier channels, and software-defined radios use error-correction techniques that approach Shannon s theoretical limit of performance. The authors describe the benefit of closed-loop measurements for a receiver when paired with a counterpart transmitter and representative channel conditions. We also describe a real-time Soft Decision Analyzer (SDA) implementation for closed-loop measurements on single- or dual- (orthogonal) channel serial data communication links. The analyzer has been used to identify, quantify, and prioritize contributors to implementation loss in real-time during the development of software defined radios.

Lansdowne, Chatwin A.; Steele, Glen F.; Zucha, Joan P.; Schlensinger, Adam M.

2012-01-01

332

SERIAL NONRIGID VASCULAR REGISTRATION USING WEIGHTED NORMALIZED MUTUAL INFORMATION  

PubMed Central

Vascular registration is a challenging problem with many potential applications. However, registering vessels accurately is difficult as they often occupy a small portion of the image and their relative motion/deformation is swamped by the displacements seen in large organs such as the heart and the liver. Our registration method uses a vessel detection algorithm to generate a vesselness image (probability of having a vessel at any given voxel) which is used to construct a weighting factor that is used to modify the intensity metric to give preference to vascular structures while maintaining the larger context. Therefore, our proposing method uses fully data-driven calculated weights and needs no prior knowledge for the weight calculation. We applied our method to the registration of serial MRI lamb images obtained from studies on tissue engineered vascular grafts and demonstrate encouraging performance as compared to non-weighted registration methods. PMID:21479163

Suh, J.W.; Scheinost, D.; Qian, X.; Sinusas, A.J.; Breuer, C.K.; Papademetris, X.

2011-01-01

333

Serial analysis of gene expression (SAGE) in rat liver regeneration  

SciTech Connect

We have applied serial analysis of gene expression for studying the molecular mechanism of the rat liver regeneration in the model of 70% partial hepatectomy. We generated three SAGE libraries from a normal control liver (NL library: 52,343 tags), from a sham control operated liver (Sham library: 51,028 tags), and from a regenerating liver (PH library: 53,061 tags). By SAGE bioinformatics analysis we identified 40 induced genes and 20 repressed genes during the liver regeneration. We verified temporal expression of such genes by real time PCR during the regeneration process and we characterized 13 induced genes and 3 repressed genes. We found connective tissue growth factor transcript and protein induced very early at 4 h after PH operation before hepatocytes proliferation is triggered. Our study suggests CTGF as a growth factor signaling mediator that could be involved directly in the mechanism of liver regeneration induction.

Cimica, Velasco [Georg-August-University of Goettingen, Department of Gastroenterology and Endocrinology, Robert Koch Str. 40, 37075 Goettingen (Germany)]. E-mail: vcimica@aecom.yu.edu; Batusic, Danko [Georg-August-University of Goettingen, Department of Gastroenterology and Endocrinology, Robert Koch Str. 40, 37075 Goettingen (Germany); Haralanova-Ilieva, Borislava [Georg-August-University of Goettingen, Department of Gastroenterology and Endocrinology, Robert Koch Str. 40, 37075 Goettingen (Germany); Chen, Yonglong [Georg-August-University of Goettingen, Department of Developmental Biochemistry, Justus-von-Liebig-Weg 11, 37077 Goettingen (Germany); Hollemann, Thomas [Georg-August-University of Goettingen, Department of Developmental Biochemistry, Justus-von-Liebig-Weg 11, 37077 Goettingen (Germany); Pieler, Tomas [Georg-August-University of Goettingen, Department of Developmental Biochemistry, Justus-von-Liebig-Weg 11, 37077 Goettingen (Germany); Ramadori, Giuliano [Georg-August-University of Goettingen, Department of Gastroenterology and Endocrinology, Robert Koch Str. 40, 37075 Goettingen (Germany)

2007-08-31

334

Serially transplantable chemically induced rat islet cell tumor  

SciTech Connect

A serially transplantable, chemically induced pancreatic islet cell tumor was developed in Lewis rats. The original tumor was induced by the administration of streptozotocin and nicotinamide. It was subsequently maintained by ip or sc transplantation of tissue fragments into recipient animals. They were well encapsulated, without gross evidence of metastasis. Peroxidase immunocytochemical staining revealed a predominance of insulin-positive cells. Somatostatin-positive cells were also present and varied widely in numbers between different tumors. On electron microscopy, cells containing secretory granules, indistinguishable from nonneoplastic ..beta..-cells, were most abundant. Tumor extracts contained an average of 3260 ..mu..g insulin, 22.6 ..mu..g somatostatin, and 0.84 ..mu..g glucagon per g wet wt of tissue.

Chick, W.L. (Harvard Medical School, Boston, MA); Appel, M.C.; Weir, G.C.; Like, A.A.; Lauris, V.; Porter, J.G.; Chute, R.N.

1980-10-01

335

The evolution of photosynthesis in chromist algae through serial endosymbioses.  

PubMed

Chromist algae include diverse photosynthetic organisms of great ecological and social importance. Despite vigorous research efforts, a clear understanding of how various chromists acquired photosynthetic organelles has been complicated by conflicting phylogenetic results, along with an undetermined number and pattern of endosymbioses, and the horizontal movement of genes that accompany them. We apply novel statistical approaches to assess impacts of endosymbiotic gene transfer on three principal chromist groups at the heart of long-standing controversies. Our results provide robust support for acquisitions of photosynthesis through serial endosymbioses, beginning with the adoption of a red alga by cryptophytes, then a cryptophyte by the ancestor of ochrophytes, and finally an ochrophyte by the ancestor of haptophytes. Resolution of how chromist algae are related through endosymbioses provides a framework for unravelling the further reticulate history of red algal-derived plastids, and for clarifying evolutionary processes that gave rise to eukaryotic photosynthetic diversity. PMID:25493338

Stiller, John W; Schreiber, John; Yue, Jipei; Guo, Hui; Ding, Qin; Huang, Jinling

2014-01-01

336

Assessing sleep consciousness within subjects using a serial awakening paradigm.  

PubMed

Dreaming-a particular form of consciousness that occurs during sleep-undergoes major changes in the course of the night. We aimed to outline state-dependent features of consciousness using a paradigm with multiple serial awakenings/questionings that allowed for within as well as between subject comparisons. Seven healthy participants who spent 44 experimental study nights in the laboratory were awakened by a computerized sound at 15-30 min intervals, regardless of sleep stage, and questioned for the presence or absence of sleep consciousness. Recall without content ("I was experiencing something but do not remember what") was considered separately. Subjects had to indicate the content of the most recent conscious experience prior to the alarm sound and to estimate its duration and richness. We also assessed the degree of thinking and perceiving, self- and environment-relatedness and reflective consciousness of the experiences. Of the 778 questionings, 5% were performed during wakefulness, 2% in stage N1, 42% in N2, 33% in N3, and 17% in rapid eye movement (REM) sleep. Recall with content was reported in 34% of non-REM and in 77% of REM sleep awakenings. Sleep fragmentation inherent to the study design appeared to only minimally affect the recall of conscious experiences. Each stage displayed a unique combination of characteristic features of sleep consciousness. In conclusion, our serial awakening paradigm allowed us to collect a large and representative sample of conscious experiences across states of being. It represents a time-efficient method for the study of sleep consciousness that may prove particularly advantageous when combined with techniques such as functional MRI and high-density EEG. PMID:23970876

Siclari, Francesca; Larocque, Joshua J; Postle, Bradley R; Tononi, Giulio

2013-01-01

337

Male Stereotypes in Radio Serials of the 1930s and 1940s.  

ERIC Educational Resources Information Center

Because they tend to reflect dominant cultural values that are more obvious and taken for granted by historians, male stereotypes in radio serials, or "soap operas," have been ignored. They are prevalent, however, especially in the representative "Golden Age" productions of Anne and Frank Hummert. The Hummerts produced 46% of the serials current…

St John, Jacqueline

338

Automated Serials Control at the Indian Institutes of Technology: An Overview  

ERIC Educational Resources Information Center

Purpose: The purpose of this paper is to highlight the functional attributes of the automated serials control systems of the libraries in seven Indian Institutes of Technology (IITs) and provide a comparative analysis. Design/methodology/approach: Features of the serials control modules of the library management systems (LMSs) in use in the…

Ghosh, Tapas Kumar; Panda, K. C.

2011-01-01

339

Psychopathology in Childhood and Adolescence as Reflected in Projected Afterimage Serials.  

ERIC Educational Resources Information Center

A serial visual afterimage (AI) test was administered to 136 normal and 75 anxiety-ridden children 4-16 years of age. The scoring of the AI serials involved signs of primitive functioning (size-constant and positive AIs), anxiety (large and dark AIs together with primitive AIs in older children) and process discontinuity (intermittent regressions…

Smith, Gudmund J. W.; Danielsson, Anna

340

An econometric model of serial correlation and illiquidity in hedge fund returns  

Microsoft Academic Search

The returns to hedge funds and other alternative investments are often highly serially correlated. In this paper, we explore several sources of such serial correlation and show that the most likely explanation is illiquidity exposure and smoothed returns. We propose an econometric model of return smoothing and develop estimators for the smoothing profile as well as a smoothing-adjusted Sharpe ratio.

Mila Getmansky; Andrew W. Lo; Igor Makarov

2004-01-01

341

Interference Effects in the Memory for Serially Presented Locations in Clark's Nutcrackers, Nucifraga columbiana  

Microsoft Academic Search

The authors tested the spatial memory of serially presented locations in Clark's nutcrackers (Nucifraga columbiana). Birds were serially presented with locations in an open room. The authors buried a seed in a sand-filled cup at each location and then tested nutcrackers for their memory for each location in the list by using the cluster method. For each item in the

Jody L. Lewis; Alan C. Kamil

2006-01-01

342

Serial Monogamy as Polygyny or Polyandry?: Marriage in the Tanzanian Pimbwe  

E-print Network

more about human nature by studying serial monogamy with ahumans, predictions are derived from conventional parental investment theory regarding expected outcomes associated with serial monogamy andMonogamy How do these recent developments within the nonhuman literature affect the way we analyze human

Borgerhoff Mulder, Monique

2009-01-01

343

Using Signal Detection Theory to Model Changes in Serial Learning of Radiological Image Interpretation  

ERIC Educational Resources Information Center

Signal detection theory (SDT) parameters can describe a learner's ability to discriminate (d[prime symbol]) normal from abnormal and the learner's criterion ([lambda]) to under or overcall abnormalities. To examine the serial changes in SDT parameters with serial exposure to radiological cases. 46 participants were recruited for this study: 20…

Boutis, Kathy; Pecaric, Martin; Seeto, Brian; Pusic, Martin

2010-01-01

344

High-Speed Serial AER on FPGA Hans Kristian Otnes Berge, Philipp Hafliger  

E-print Network

High-Speed Serial AER on FPGA Hans Kristian Otnes Berge, Philipp H¨afliger University of Oslo using a low voltage differential signaling (LVDS) interface on a commercial FPGA. Many of the latest with an FPGA that handles the external high speed serial link. We judge the design effort to be much smaller

Häfliger, Philipp

345

Visual and Phonological Similarity Effects in Verbal Immediate Serial Recall: A Test with Kanji Materials  

ERIC Educational Resources Information Center

In a series of three experiments, native speakers of Japanese performed serial ordered written recall of visually presented Japanese kanji characters that varied systematically in visual and phonological similarity. Overall effects of phonological similarity were observed for retention of serial order under silent reading in Experiments 1 and 3…

Saito, Satoru; Logie, Robert H.; Morita, Aiko; Law, Anna

2008-01-01

346

The Moral Responsibility of Psychopathic Serial Killers: A Case Study in Dexter  

Microsoft Academic Search

Dexter Morgan is a serial killer, but he may not be blameworthy for his actions There are two possible explanations that could absolve Dexter of moral responsibility: (1) His inability to empathize with others makes it so that he cannot make appropriate moral decisions. Or (2) his serial killing tendencies are determined in nature, set off by events of which

Matthew Hollander

2011-01-01

347

Analysis of Readex's Serial Set MARC Records: Improving the Data for the Library Catalog  

ERIC Educational Resources Information Center

Colorado State University Libraries (CSUL) purchased the digitized "United States Congressional Serial Set," 1817-1994 and "American State Papers" (1789-1838) from the Readex Division of NewsBank, Inc. and, once funds and records were available, the accompanying MARC records. The breadth of information found in the "Serial Set" is described, along…

Draper, Daniel; Lederer, Naomi

2013-01-01

348

Edinburgh Research Explorer Quantitative Serial MRI of the Treated Fibroid Uterus  

E-print Network

Edinburgh Research Explorer Quantitative Serial MRI of the Treated Fibroid Uterus Citation Serial MRI of the Treated Fibroid Uterus' PLoS One, vol 9, no. 3, e89809., 10.1371/journal.pone.0089809 of the Treated Fibroid Uterus Kirsty I. Munro1. , Michael J. Thrippleton1,2. , Alistair R. W. Williams1

Maizels, Rick

349

All optical histology of brain tissue: Serial ablation and multiphoton imaging with femtosecond laser pulses  

E-print Network

All optical histology of brain tissue: Serial ablation and multiphoton imaging with femtosecond pulses for serial histology. Successive iterations of multiphoton imaging and ablation provide techniques in histology involve the manual slicing of frozen or embedded tissue, which is both labor

Kleinfeld, David

350

All optical histology : Serial ablation and multiphoton imaging of neuronal tissue with femtosecond laser pulses  

E-print Network

All optical histology : Serial ablation and multiphoton imaging of neuronal tissue with femtosecond pulses to serially image and ablate neuronal tissue. This allows histological imaging throughout techniques in histology involve the manual slicing of frozen or embedded tissue, which is labor intensive

Kleinfeld, David

351

The Effect of Rate of Presentation on Digit Serial Recall in Reading Retarded Children.  

ERIC Educational Resources Information Center

This study examined the effect of presentation rate on accuracy of digit serial recall and on serial position curves of digit strings of different lengths with 18 boys classified as reading retarded and a comparison group of children (ages for both groups averaged 11 years) who read at grade level. The results indicated that normal children…

Gan, Jennifer; Tymchuk, Alexander J.

352

Theoretical consideration of female sexual predator serial killers in the United States  

Microsoft Academic Search

Sexual predators represent the embodiment of the cultural definition of serial killing. In considering the female sexual predator serial killer, a review of the limited literature found a clear distinction between women acting alone versus in partnership. Several theories offered to explain the behavior of women in teams include shared psychotic disorder, Stockholm syndrome, posttraumatic stress disorder (PTSD), battered woman

Heather Silvio; Kathy McCloskey; Julia Ramos-Grenier

2006-01-01

353

Researching the multiple murderer: A comprehensive bibliography of books on specific serial, mass, and spree killers  

Microsoft Academic Search

True crime books are a useful source for researching serial killers. Unfortunately, many of these books do not include the name of the killer in the title, making it difficult to find them in a literature search. To make researching serial killers easier, we have created a comprehensive bibliography of true crime books on specific multiple murderers. This was done

Michael G. Aamodt; Christina Moyse

2003-01-01

354

African Americans and Serial Killing in the MediaThe Myth and the Reality  

Microsoft Academic Search

There were many expressions of shock and surprise voiced in the media in 2002 when the “D.C. Sniper” turned out to be two Black males. Two of the stereotypes surrounding serial killers are that they are almost always White males and that African American males are barely represented in their ranks. In a sample of 413 serial killers operating in

Anthony Walsh

2005-01-01

355

Construing the Construction Processes of Serial Killers and Other Violent Offenders: 1. The Analysis of Narratives  

Microsoft Academic Search

This article presents analyses of two narratives: a book written by a serial killer, Ian Brady, and an autobiographical account written by a serially violent offender. In both cases, the narrative was subjected to a content analysis and converted to a textual grid. It is argued that narratives provide not only a means of better understanding the violent offender's view

David Winter; Guillem Feixas; Rita Dalton; Livia Jarque-Llamazares; Esteban Laso; Clare Mallindine; Sarah Patient

2007-01-01

356

Antisocial personality disorder in serial killers: The thrill of the kill  

Microsoft Academic Search

Serial killing is a heinous crime that is difficult to understand. Sadistic serial murderers often rape, torture, and brutalize their victims before the murder even occurs. This paper addresses the motives behind such inhumane acts. By researching how the killer's abusive childhood led to the sadistic need for power and control, one can better understand how the individual developed the

Cassandra L. Simons

2001-01-01

357

Male Serial HomicideThe Influence of Cultural and Structural Variables  

Microsoft Academic Search

Psychiatric approaches have usually been used to explain male serial homicide. But multifactor explanations of the phenomenon suggest that aspects of culture and social structure may also play important roles. The current study attempts to evaluate the multifactor approach by examining whether cultural and structural variables might contribute to explaining the considerable interstate differences in the incidence of male serial

James DeFronzo; Ashley Ditta; Lance Hannon; Jane Prochnow

2007-01-01

358

Oblio: A Sparse Direct Solver Library for Serial and Parallel Computations  

E-print Network

Oblio: A Sparse Direct Solver Library for Serial and Parallel Computations Florin Dobrian1 Center Abstract. We present Oblio, a sparse direct solver library running in both serial an parallel the solution of sparse linear systems of equations represents the key computation in several critical industry

Pothen, Alex

359

Evidence for a clade composed of molluscs with serially repeated structures: Monoplacophorans are related to chitons  

Microsoft Academic Search

Monoplacophorans are among the rarest members of the phylum Mollusca. Previously only known from fossils since the Cambrian, the first living monoplacophoran was discovered during the famous second Galathea deep-sea expedition. The anatomy of these molluscs shocked the zoological community for presenting serially repeated gills, nephridia, and eight sets of dorsoventral pedal retractor muscles. Seriality of organs in supposedly independent

Gonzalo Giribet; Akiko Okusu; Annie R. Lindgren; Stephanie W. Huff; Michael Schrödl; Michele K. Nishiguchi

2006-01-01

360

Optimal Allocation of Heat Exchanger Inventory in a Serial Type Diabatic Distillation Column  

E-print Network

Optimal Allocation of Heat Exchanger Inventory in a Serial Type Diabatic Distillation Column Edward the column . We have previously shown (Jimenez et al. 2003) that optimaloperation of serial heat exchangers total heat exchanger area in different trays and calculate the optimal allocation of a given heat

Salamon, Peter

361

The relationship between serial monogamy and rape in the United States (19601995)  

E-print Network

The relationship between serial monogamy and rape in the United States (1960­1995) Philip T. Starks cannot secure females through traditional methods may seek alternatives, such as rape, to ensure gene) rates of divorce and rape correlate positively. The former result suggests that serial monogamy

Starks, Philip

362

ON SERIAL AND PARALLEL IMPLEMENTATIONS OF THE ERLANG FIXED POINT ITERATION SCHEME  

E-print Network

ON SERIAL AND PARALLEL IMPLEMENTATIONS OF THE ERLANG FIXED POINT ITERATION SCHEME Andrew G Hart of the weighting constant. Finally, a comparison between the serial implementation and a number of parallel, including cellular and mobile radio networks, database management systems, computer networks and circuit

Pollett, Phil

363

Endoscopic laser surgery versus serial amniocenteses in the treatment of severe twin-twin transfusion syndrome  

Microsoft Academic Search

Objective: Severe twin-twin transfusion can be treated by either serial amniocenteses with removal of large volumes of amniotic fluid or by endoscopic laser coagulation of the communicating vessels. We investigated the benefit of laser surgery in comparison to serial amniocenteses in terms of pregnancy outcome. Study Design: The data used in this comparative study were collected from 116 patients with

Kurt Hecher; Hanno Plath; Thomas Bregenzer; Manfred Hansmann; Bernhard J. Hackelöer

1999-01-01

364

Evidence for a clade composed of molluscs with serially repeated structures: Monoplacophorans  

E-print Network

Evidence for a clade composed of molluscs with serially repeated structures: Monoplacophorans. The anatomy of these molluscs shocked the zoological community for presenting serially repeated gills of molluscs ever assembled, clearly illustrate that monoplacophorans and chitons form a clade. This ``Serialia

Nishiguchi, Michele

365

The case of Jeffrey Dahmer: sexual serial homicide from a neuropsychiatric developmental perspective.  

PubMed

Sexual serial homicidal behavior has received considerable attention during the last three decades. Substantial progress has been made in the development of methods aimed at identifying and apprehending individuals who exhibit these behaviors. In spite of these advances, the origins of sexual serial killing behavior remain for the most part unknown. In this article we propose a biopsychosocial psychiatric model for understanding the origins of sexual serial homicidal behavior from both neuropsychiatric and developmental perspectives, using the case of convicted serial killer Jeffrey Dahmer as the focal point. We propose that his homicidal behavior was intrinsically associated with autistic spectrum psychopathology, specifically Asperger's disorder. The relationship of Asperger's disorder to other psychopathology and to his homicidal behavior is explored. We discuss potential implications of the proposed model for the future study of the causes of sexual serial homicidal crime. PMID:12455663

Silva, J Arturo; Ferrari, Michelle M; Leong, Gregory B

2002-11-01

366

IEEE 1394/firewire a low cost, high speed, digital serial bus  

SciTech Connect

Does the world need yet another 1/0 bus standard? If you need fast and cheap serial video communication, then the answer is yes. As technology advances, so too must data transport mechanisms advance. You can`t expect RS-232 to support real-time digital video, and if you can`t afford expensive professional serial video interfaces, (such as Sony`s Serial Digital Interface), Firewire may be a good solution. IEEE 1394, or commonly known as Firewire, is a general purpose serial bus that meets many of the 1/0 needs of today`s video and multimedia developers. For those of you who only read the first paragraph, here`s Firewire in a nutshell: It provides a guaranteed transfer rate of 10OMbps or 20OMbps of digital data (such as video direct from camera to computer), over an inexpensive, non-proprietary serial bus. Here is a list of its features.

Gaunt, R.

1997-05-01

367

Psychological profiling of offender characteristics from crime behaviors in serial rape offences.  

PubMed

Criminal psychological profiling has progressively been incorporated into police procedures despite a dearth of empirical research. Indeed, in the study of serial violent crimes for the purpose of psychological profiling, very few original, quantitative, academically reviewed studies actually exist. This article reports on the analysis of 62 incidents of serial sexual assault. The statistical procedure of multidimensional scaling was employed in the analysis of this data, which in turn produced a five-cluster model of serial rapist behavior. First, a central cluster of behaviors were identified that represent common behaviors to all patterns of serial rape. Second, four distinct outlying patterns were identified as demonstrating distinct offence styles, these being assigned the following descriptive labels brutality, intercourse, chaotic, and ritual. Furthermore, analysis of these patterns also identified distinct offender characteristics that allow for the use of empirically robust offender profiles in future serial rape investigations. PMID:12113160

Kocsis, Richard N; Cooksey, Ray W; Irwin, Harvey J

2002-04-01

368

Excitons in novel diluted magnetic semiconductor quantum structures  

Microsoft Academic Search

We report on the growth and basic characterization of new quantum well structures made of diluted magnetic semiconductors. The novelty of the structures has two aspects. First, by molecular beam epitaxy we attempted to grow diluted magnetic semiconductor materials containing chromium ions as the magnetic component. We succeeded in obtaining materials containing up to 3 atomic percent of Cr in

Tomasz Wojtowicz; Grzegorz Karczewski; Jacek Kossut

1997-01-01

369

THE DILUTION/FLUSHING TECHNIQUE IN LAKE RESTORATION  

EPA Science Inventory

Dilution/flushing has been documented as an effective restoration technique for Moses and Green Lakes in Washington State. The dilution water added in both lakes was low in nitrogen and phosphorus content relative to the lake or normal input water. Consequently, lake nutrient con...

370

Effect of Homeopathic Dilutions on Subcellular Enzymatic Activity  

Microsoft Academic Search

The activity of various inhibitors on several subcellular enzymes was studied. First we determined the inhibitory concentration required to reduce maximum enzymatic activity by 50%, then the effect of various hahnemannian dilutions of the same inhibitory agent was tested. Seven inhibitory agents were tested in this way on seven different enzymatic systems. No effects of these hahnemannian dilutions were shown.

C. Petit; P. Belon; R. Got

1989-01-01

371

Dilution Ratios for HB Line Phase I Eductor System  

Microsoft Academic Search

HB Line Phase I product transfer includes an eductor which transfers liquid from Product Hold Tank (PHT) RT-33 or RT-34 to Tank 11.1. The eductor also dilutes the liquid from the PHT with eductant. Dilution must be reliably controlled because of criticality concerns with H Canyon Tanks. The eductor system, which contains a 1 inch Model 264 Schutte and Koerting

Steimke

2002-01-01

372

Effects of dilution on vehicle emissions of primary particles  

NASA Astrophysics Data System (ADS)

Dilution of primary aerosols from vehicles into the ambient atmosphere can change their physical and chemical characteristics. In order to study these processes, experiments were conducted in an engine testing facility at Environment Canada in Ottawa, Ontario. Exhaust from a light duty diesel engine was vented into a constant volume sampling (CVS) system where it underwent primary dilution at an ambient temperature of 25oC, leading to a primary dilution ratio of 10-15. From the CVS, the exhaust was further diluted using a combination of a Dekati ejection diluter and mixing with zero air in a flow tube, achieving secondary dilution ratios of up to 3000. Particle and gas measurements were made through multi-ports in the CVS and the flow tube using an SMPS, FMPS, AMS, and SP2, and instruments to measure CO, CO2, NOx, and total hydrocarbons (THC). Preliminary results indicate that regardless of dilution ratios, primary particles contain significant amounts of organic material that appear to reside on small black carbon cores. With increasing dilution ratios, the primary particle sizes become progressively smaller, suggesting volatilization of the adsorbed organic material. Results from various engine operating modes (simulating different driving conditions) will be presented.

Hayden, K. L.; Li, S.; Liggio, G.; McCurdy, M.; Chan, T.; Rostkowski, J.

2009-12-01

373

A PRESSURIZED PROPORTIONAL DILUTER FOR AQUATIC TOXICOLOGICAL STUDIES  

EPA Science Inventory

A half-liter proportional diluter using positive pressure was designed and tested. Its primary siphons are activated by a pulse of pressure instead of by a partial vacuum as in conventional diluters. This method eliminated the need for venturi tubes, vacuum manifolds, and individ...

374

Magnetization Studies of Dilute Magnetic Materials  

NASA Astrophysics Data System (ADS)

Magnetization studies of several dilute magnetic materials are presented. The materials are: Zn _{1-x}Fe_{x }Se,Cu_2Zn_ {1-x}Mn_{x}Sn S_4, and Mn_{1 -x}rm Zn_{it x}F_2. The magnetization of cubic Zn_ {1-x}Fe_{x}Se with x = 0.003 and 0.007 was measured at temperatures 2 <= T _sp{ ~}{<} 50 K, in fields H parallel to the (100) and (111) directions. At low temperatures, M is anisotropic in high fields; the anisotropy disappears at low fields, and at all fields for high temperatures. At given values of T and H for which the anisotropy exists, M is greater if H | (100) than if H | (111). The maximum observed value of M_{[ 100]}/M_{[ 111] } is 1.19, at H cong 150 kOe and T = 4.2 K. The results agree well with calculated values of M based on crystal field theory and the assumption that only isolated Fe^ {++} ions contribute to the magnetization. Slight differences between theory and experiment remain. Magnetization measurements were performed for Cu_2Zn_{1-x }Mn_{x}SnS _4, dilute antiferromagnets with the tetragonal stannite structure, with x = 1 and 0.88. Data were taken at temperatures 1.9 <= T <= 350 K in fields up to 50 kOe, and at T = 0.6, 1.4, and 4.2 K up to 300 kOe. They indicate that the material is an antiferromagnet with the easy axis along the c axis. For x = 1, T_{N} = 8.8 +/- 0.1 K, the spin flop occurs at 28 kOe, and the critical field is 245.5 +/- 2 kOe. Mean field theory describes this sample well, and calculations show that the dipole-dipole interaction accounts for 61% of the anisotropy. The sample with x = 0.88 showed the presence of a large number of bound magnetic polarons. The dilute antiferromagnets Mn_ {1-x}Zn_{x}F _2 exhibit a remanent magnetization M_{r} along the easy axis at temperatures below T_{N}. This M_{r} begins to saturate in axial fields as low as H_{rm axial} ~ 1 Oe. M_ {r} is a function of temperature and the axial field H_{rm axial}(T _{N}) present when cooling through T_{N}. Curves of M _{r} vs. T for x = 0.51 and x = 0.25 have the same shape for all values of H_{ rm axial}(T_{N}). Values of beta_{r}, the critical exponent governing M_{r} , are obtained from curve fitting, and are between 0.35 and 0.40. Several theories are proposed to account for M_{r}, but none is able to explain all observations.

Fries, Thomas Hall

1995-01-01

375

Dilute Surfactant Methods for Carbonate Formations  

SciTech Connect

There are many fractured carbonate reservoirs in US (and the world) with light oil. Waterflooding is effective in fractured reservoirs, if the formation is water-wet. Many fractured carbonate reservoirs, however, are mixed-wet and recoveries with conventional methods are low (less than 10%). The process of using dilute anionic surfactants in alkaline solutions has been investigated in this work for oil recovery from fractured oil-wet carbonate reservoirs both experimentally and numerically. This process is a surfactant-aided gravity drainage where surfactant diffuses into the matrix, lowers IFT and contact angle, which decrease capillary pressure and increase oil relative permeability enabling gravity to drain the oil up. Anionic surfactants have been identified which at dilute concentration of 0.05 wt% and optimal salinity can lower the interfacial tension and change the wettability of the calcite surface to intermediate/water-wet condition as well or better than the cationic surfactant DTAB with a West Texas crude oil. The force of adhesion in AFM of oil-wet regions changes after anionic surfactant treatment to values similar to those of water-wet regions. The AFM topography images showed that the oil-wetting material was removed from the surface by the anionic surfactant treatment. Adsorption studies indicate that the extent of adsorption for anionic surfactants on calcite minerals decreases with increase in pH and with decrease in salinity. Surfactant adsorption can be minimized in the presence of Na{sub 2}CO{sub 3}. Laboratory-scale surfactant brine imbibition experiments give high oil recovery (20-42% OOIP in 50 days; up to 60% in 200 days) for initially oil-wet cores through wettability alteration and IFT reduction. Small (<10%) initial gas saturation does not affect significantly the rate of oil recovery in the imbibition process, but larger gas saturation decreases the oil recovery rate. As the core permeability decreases, the rate of oil recovery reduces, and this reduction can be scaled by the gravitational dimensionless time. Mechanistic simulation of core-scale surfactant brine imbibition matches the experimentally observed imbibition data. In-situ distributions observed through simulation indicate that surfactant diffusion (which depends on temperature and molecular weight) is the rate limiting step. Most of the oil is recovered through gravitational forces. Oil left behind at the end of this process is at its residual oil saturation. The capillary and Bond numbers are not large enough to affect the residual oil saturation. At the field-scale, 50% of the recoverable oil is produced in about 3 years if the fracture spacing is 1 m and 25% if 10 m, in the example simulated. Decreasing fracture spacing and height, increasing permeability, and increasing the extent of wettability alteration increase the rate of oil recovery from surfactant-aided gravity drainage. This dilute surfactant aided gravity-drainage process is relatively cheap. The chemical cost for a barrel of oil produced is expected to be less than $1.

Kishore K. Mohanty

2006-02-01

376

Zinc oxide based diluted magnetic semiconductors  

NASA Astrophysics Data System (ADS)

During my graduate research I have synthesized materials known as diluted magnetic semiconductors (DMS) as epitaxial thin film structures using the process of pulsed laser deposition (PLD). These materials are envisioned to be of importance in the emerging field of spintronics where the charge as well as the spin of the charge carriers can be combined to yield unique functionalities to yield novel devices including, on-chip memories, ultra-low power devices etc. The material of interest in this dissertation was zinc oxide, a wide bandgap optoelectronic semiconductor. ZnO has a bandgap of 3.3 eV. It is an ideal candidate for spintronics applications, because Zn is the last of the first row transition metals, which leads to pretty high solubility of transition metals such as Co, Mn and V in ZnO. In a diluted magnetic semiconductor a fraction of the host atoms is substituted by the transition metal dopant ion. We have found that we can synthesize very high quality, single phase and single crystalline Zn(TM)O thin films on basal plane sapphire single crystals (alpha-Al 2O3). We have analyzed the magnetic properties of the three systems of ZnVO, ZnCoO and ZnMnO and found that ZnCoO and ZnMnO exhibit ferromagnetic ordering up to room temperature, when synthesized under high vacuum. In these conditions, the samples have a reasonable concentration of point defects which drive ZnO to n-type conductivity. By a combination of in-situ and ex-situ variation of parameters we have been able to tune the electronic and magnetic properties of these systems. From these studies we conclude that the main mechanism of magnetic ordering in these DMS materials is through a combination of defect related carrier induced exchange and bound magnetic polaron exchange. Device structures were fabricated using the as deposited samples to study the possibility of spin injection through semiconductors. We have observed that at low temperatures we see a considerable effect from this phenomenon in a magnetic tunnel junction kind of configuration. Hence, this study opens up new avenues and possibilities for a variety of spintronics applications.

Ramachandran, Shivaraman

377

Diluted Magnetic Manganese Germanide for Nanostructure Devices  

NASA Astrophysics Data System (ADS)

Diluted magnetic semiconductor (DMS) materials have great potential when applied to spin-based devices, which integrate the electron charge and spin degrees of freedom. By appropriately controlling the magnetism in the semiconductor, a spin exchange switch can realize spin flipping with switching energy far less than what is needed in conventional complementary metal-oxide-semiconductor (CMOS) devices. Mn-doped Ge is a very promising candidate for such an application due to its theoretically predicted room temperature ferromagnetism and the compatibility with current CMOS technology. This thesis work mainly focuses on optimizing the material properties of MnxGe1-x thin films to achieve strong magnetization, high Curie temperature, and good film conductivity. Both ion implantation and molecular beam epitaxy (MBE)* have been used to synthesize diluted Mn xGe1-x thin films. Rapid thermal annealing was found to enhance the magnetism by incorporating more Mn ions into substitutional lattice sites. Transmission electron microscopy showed that Mn ions were highly mobile in the Ge matrix, and tended to form nanoscale clusters. MnxGe 1-x also exhibited very interesting magnetotransport properties, indicating that the ferromagnetism is closely correlated with carriers. The underlying fundamental mechanisms for the magnetism in MnxGe 1-x and its relation with microstructures will also be discussed. In order to study the carrier-mediated ferromagnetism in MnxGe 1-x, two experimental approaches were carried out: (1) B, P, and C atoms were codoped in MnxGe1-x thin films to investigate the impact of electronic dopants on ferromagnetism and electrical transport; (2) Mg and Au metal capping layers were deposited on MnxGe 1-x thin films to deplete / inject hole carriers through the metal-semiconductor interface. Both results suggested that ferromagnetism is effectively modulated by changing the hole concentration in MnxGe1-x. Additionally, a molecular dynamics (MD) simulation has been carried out for the Mn ion implantation into a Ge crystalline lattice. The dynamic change of the microstructure during the ion implantation is demonstrated, which will lead to a better understanding of how the material becomes amorphous, how the defects form and how the Mn distributes in the Ge matrix. * In collaboration with Prof. Jerrold Floro's group.

Yin, Wenjing

378

Specialized Postsynaptic Morphology Enhances Neurotransmitter Dilution and High-Frequency Signaling at an Auditory Synapse  

PubMed Central

Sensory processing in the auditory system requires that synapses, neurons, and circuits encode information with particularly high temporal and spectral precision. In the amphibian papillia, sound frequencies up to 1 kHz are encoded along a tonotopic array of hair cells and transmitted to afferent fibers via fast, repetitive synaptic transmission, thereby promoting phase locking between the presynaptic and postsynaptic cells. Here, we have combined serial section electron microscopy, paired electrophysiological recordings, and Monte Carlo diffusion simulations to examine novel mechanisms that facilitate fast synaptic transmission in the inner ear of frogs (Rana catesbeiana and Rana pipiens). Three-dimensional anatomical reconstructions reveal specialized spine-like contacts between individual afferent fibers and hair cells that are surrounded by large, open regions of extracellular space. Morphologically realistic diffusion simulations suggest that these local enlargements in extracellular space speed transmitter clearance and reduce spillover between neighboring synapses, thereby minimizing postsynaptic receptor desensitization and improving sensitivity during prolonged signal transmission. Additionally, evoked EPSCs in afferent fibers are unaffected by glutamate transporter blockade, suggesting that transmitter diffusion and dilution, and not uptake, play a primary role in speeding neurotransmission and ensuring fidelity at these synapses. PMID:24920639

Graydon, Cole W.; Cho, Soyoun; Diamond, Jeffrey S.; Kachar, Bechara; von Gersdorff, Henrique

2014-01-01

379

Specialized postsynaptic morphology enhances neurotransmitter dilution and high-frequency signaling at an auditory synapse.  

PubMed

Sensory processing in the auditory system requires that synapses, neurons, and circuits encode information with particularly high temporal and spectral precision. In the amphibian papillia, sound frequencies up to 1 kHz are encoded along a tonotopic array of hair cells and transmitted to afferent fibers via fast, repetitive synaptic transmission, thereby promoting phase locking between the presynaptic and postsynaptic cells. Here, we have combined serial section electron microscopy, paired electrophysiological recordings, and Monte Carlo diffusion simulations to examine novel mechanisms that facilitate fast synaptic transmission in the inner ear of frogs (Rana catesbeiana and Rana pipiens). Three-dimensional anatomical reconstructions reveal specialized spine-like contacts between individual afferent fibers and hair cells that are surrounded by large, open regions of extracellular space. Morphologically realistic diffusion simulations suggest that these local enlargements in extracellular space speed transmitter clearance and reduce spillover between neighboring synapses, thereby minimizing postsynaptic receptor desensitization and improving sensitivity during prolonged signal transmission. Additionally, evoked EPSCs in afferent fibers are unaffected by glutamate transporter blockade, suggesting that transmitter diffusion and dilution, and not uptake, play a primary role in speeding neurotransmission and ensuring fidelity at these synapses. PMID:24920639

Graydon, Cole W; Cho, Soyoun; Diamond, Jeffrey S; Kachar, Bechara; von Gersdorff, Henrique; Grimes, William N

2014-06-11

380

S.IM.PL Serialization: Type System Scopes Encapsulate Cross-Language, Multi-Format Information Binding  

E-print Network

repetitive, tedious code to map loosely-typed serialized data to strongly-typed program objects. We developed S.IM.PL Serialization, a cross-language multi-format information binding framework to relieve developers from the burdens associated...

Shahzad, Nabeel

2012-02-14

381

DILUTE SURFACTANT METHODS FOR CARBONATE FORMATIONS  

SciTech Connect

There are many carbonate reservoirs in US (and the world) with light oil and fracture pressure below its minimum miscibility pressure (or reservoir may be naturally fractured). Many carbonate reservoirs are naturally fractured. Waterflooding is effective in fractured reservoirs, if the formation is water-wet. Many fractured carbonate reservoirs, however, are mixed-wet and recoveries with conventional methods are low (less than 10%). Thermal and miscible tertiary recovery techniques are not effective in these reservoirs. Surfactant flooding (or huff-n-puff) is the only hope, yet it was developed for sandstone reservoirs in the past. The goal of this research is to evaluate dilute (hence relatively inexpensive) surfactant methods for carbonate formations and identify conditions under which they can be effective. Laboratory imbibition tests show that imbibition rate is not very sensitive to the surfactant concentration (in the range of 0.05-0.2 wt%) and small amounts of trapped gas saturation. It is however very sensitive to oil permeability and water-oil-ratio. Less than 0.5 M Na2CO3 is needed for in situ soap generation and low adsorption; NaCl can be added to reach the necessary total salinity. The simulation result matches the laboratory imbibition experimental data. Small fracture spacing and high permeability would be needed for high rate of recovery.

Kishore K. Mohanty

2005-07-01

382

Dilute Surfactant Methods for Carbonate Formations  

SciTech Connect

There are many carbonate reservoirs in US (and the world) with light oil and fracture pressure below its minimum miscibility pressure (or reservoir may be naturally fractured). Many carbonate reservoirs are naturally fractured. Waterflooding is effective in fractured reservoirs, if the formation is water-wet. Many fractured carbonate reservoirs, however, are mixed-wet and recoveries with conventional methods are low (less than 10%). Thermal and miscible tertiary recovery techniques are not effective in these reservoirs. Surfactant flooding (or huff-n-puff) is the best hope, yet it was developed for sandstone reservoirs in the past. The goal of this research is to evaluate dilute (hence relatively inexpensive) surfactant methods for carbonate formations and identify conditions under which they can be effective. Laboratory-scale surfactant brine imbibition experiments give high oil recovery (35-62% OOIP) for initially oil-wet cores through wettability alteration and IFT reduction. Core-scale simulation results match those of the experiments. Initial capillarity-driven imbibition gives way to a final gravity-driven process. As the matrix block height increases, surfactant alters wettability to a lesser degree, or permeability decreases, oil production rate decreases. The scale-up to field scale will be further studied in the next quarter.

Kishore K. Mohanty

2005-10-01

383

Two unusual pediatric cases of dilutional hyponatremia.  

PubMed

Dilutional hyponatremia, although not uncommon, is an underestimated problem in the pediatric population. In most cases, it results from excessive hydration or water retention, also described as the so-called water intoxication. One of the most known causes is the use of desmopressin in enuretic children. This drug enhances the free water reabsorption in the renal collecting ducts. The addition of the anticholinergic agent oxybutynin aggravated the condition by causing a dry mouth with excessive thirst and water intake in our first case. Dietary water overconsumption, either voluntary or involuntary, is a phenomenon seen in formula-fed babies. But in our second case, a game involving forced ingestion of large amounts of water had serious consequences including hyponatremia-related coma. An effort should therefore be made to inform caretakers about the risks of these games. These cases, provoked by rather unusual and peculiar causes, illustrate again that electrolytes and especially serum [Na(+)] are key points to be determined in a child with diminished consciousness. Moreover, an accurate history including the intake of medication and dietary information should be made. PMID:20622630

Boetzkes, Sanne; Van Hoeck, Koen; Verbrugghe, Walter; Ramet, José; Wojciechowski, Marek; Jorens, Philippe G

2010-07-01

384

DILUTE SURFACTANT METHODS FOR CARBONATE FORMATIONS  

SciTech Connect

There are many carbonate reservoirs in US (and the world) with light oil and fracture pressure below its minimum miscibility pressure (or reservoir may be naturally fractured). Many carbonate reservoirs are naturally fractured. Waterflooding is effective in fractured reservoirs, if the formation is water-wet. Many fractured carbonate reservoirs, however, are mixed-wet and recoveries with conventional methods are low (less than 10%). Thermal and miscible tertiary recovery techniques are not effective in these reservoirs. Surfactant flooding (or huff-n-puff) is the only hope, yet it was developed for sandstone reservoirs in the past. The goal of this research is to evaluate dilute (hence relatively inexpensive) surfactant methods for carbonate formations and identify conditions under which they can be effective. Simulation studies indicate that both wettability alteration and gravity-driven flow play significant role in oil recovery from fractured carbonates. Anionic surfactants (Alfoterra 35, 38) recover about 55% of the oil in about 150 days by imbibition driven by wettability alteration and low tension in the core-scale. Anionic surfactant, Alfoterra-68, recovers about 40% of the oil by lower tension aided gravity-driven imbibition in the core-scale. Cationic surfactant, DTAB recovers about 35% of the oil. Plans for the next quarter include conducting simulation and imbibition studies.

Kishore K. Mohanty

2004-10-01

385

Chain Dynamics in a Dilute Magnetorheological Fluid  

NASA Technical Reports Server (NTRS)

The structure, formation, and dynamics of dilute, mono-dispersive ferrofluid emulsions in an external magnetic field have been investigated using dynamic light scattering techniques. In the absence of the magnetic field, the emulsion particles are randomly distributed and behave like hard spheres in Brownian motion. An applied magnetic field induces a magnetic dipole moment in each particle. Dipolar interactions between particles align them into chains where correlation functions show two decay processes. The short-time decay shows the motion of straight chains as a whole where the apparent chain length increases with the applied magnetic field and the particle volume fraction. Good scaling results are obtained showing that the apparent chain length grows with time following a power law with exponent of 0.6 and depends on the applied field, particle volume fraction, and diffusion constant of the particles. The long-time decay in the correlation function shows oscillation when the chains reach a certain length with time and stiffness with threshold field This result shows that chains not only fluctuate, but move in a periodic motion with a frequency of 364 Hz at lambda = 15. It may suggest the existence of phonons. This work is the first step in the understanding of the structure formation, especially chain coarsening mechanism, of magnetorheological (MR) fluids at higher volume fractions.

Liu, Jing; Hagenbuchle, Martin

1996-01-01

386

DILUTE SURFACTANT METHODS FOR CARBONATE FORMATIONS  

SciTech Connect

There are many carbonate reservoirs in US (and the world) with light oil and fracture pressure below its minimum miscibility pressure (or reservoir may be naturally fractured). Many carbonate reservoirs are naturally fractured. Waterflooding is effective in fractured reservoirs, if the formation is water-wet. Many fractured carbonate reservoirs, however, are mixed-wet and recoveries with conventional methods are low (less than 10%). Thermal and miscible tertiary recovery techniques are not effective in these reservoirs. Surfactant flooding (or huff-n-puff) is the only hope, yet it was developed for sandstone reservoirs in the past. The goal of this research is to evaluate dilute (hence relatively inexpensive) surfactant methods for carbonate formations and identify conditions under which they can be effective. Imbibition in an originally oil-wet 2D capillary is the fastest in the case of Alf-38 and slowest in the case of DTAB (among the surfactants studied). Force of adhesion studies and contact angle measurements show that greater wettability alteration is possible with these anionic surfactants than the cationic surfactant studied. The water imbibition rate does not increase monotonically with an increase in the surfactant concentration. A numerical model has been developed that fits the rate of imbibition. Plans for the next quarter include conducting simulation and imbibition studies.

Kishore K. Mohanty

2005-01-01

387

DILUTE SURFACTANT METHODS FOR CARBONATE FORMATIONS  

SciTech Connect

There are many carbonate reservoirs in US (and the world) with light oil and fracture pressure below its minimum miscibility pressure (or reservoir may be naturally fractured). Many carbonate reservoirs are naturally fractured. Waterflooding is effective in fractured reservoirs, if the formation is water-wet. Many fractured carbonate reservoirs, however, are mixed-wet and recoveries with conventional methods are low (less than 10%). Thermal and miscible tertiary recovery techniques are not effective in these reservoirs. Surfactant flooding (or huff-n-puff) is the only hope, yet it was developed for sandstone reservoirs in the past. The goal of this research is to evaluate dilute (hence relatively inexpensive) surfactant methods for carbonate formations and identify conditions under which they can be effective. Anionic surfactants (SS-6656, Alfoterra 35, 38, 63,65,68) have been identified which can change the wettability of the calcite surface to intermediate/water-wet condition as well or better than the cationic surfactant DTAB with a West Texas crude oil in the presence of Na{sub 2}CO{sub 3}. All the carbonate surfaces (Lithographic Limestone, Marble, Dolomite and Calcite) show similar behavior with respect to wettability alteration with surfactant 4-22. Anionic surfactants (5-166, Alfoterra-33 and Alfoterra-38 and Alfoterra-68), which lower the interfacial tension with a West Texas crude oil to very low values (<10{sup -2} nM/m), have also been identified. Plans for the next quarter include conducting wettability, mobilization, and imbibition studies.

Kishore K. Mohanty

2004-01-01

388

DILUTE SURFACTANT METHODS FOR CARBONATE FORMATIONS  

SciTech Connect

There are many carbonate reservoirs in US (and the world) with light oil and fracture pressure below its minimum miscibility pressure (or reservoir may be naturally fractured). Many carbonate reservoirs are naturally fractured. Waterflooding is effective in fractured reservoirs, if the formation is water-wet. Many fractured carbonate reservoirs, however, are mixed-wet and recoveries with conventional methods are low (less than 10%). Thermal and miscible tertiary recovery techniques are not effective in these reservoirs. Surfactant flooding (or huff-n-puff) is the only hope, yet it was developed for sandstone reservoirs in the past. The goal of this research is to evaluate dilute (hence relatively inexpensive) surfactant methods for carbonate formations and identify conditions under which they can be effective. We have conducted adsorption, phase behavior, interfacial tension (IFT) and wettability studies. Addition of Na{sub 2}CO{sub 3} decreases IFT with a minimum at about 0.2 M. Addition of surfactant decreases IFT further. In the absence of surfactant the minerals are oil-wet after aging with crude oil. Addition of surfactant solution decreases the contact angle to intermediate-wet for many surfactants and water-wet for one surfactant. Addition of Na{sub 2}CO{sub 3} decreases anionic surfactant adsorption on calcite surface. Plans for the next quarter include conducting core adsorption, phase behavior, wettability and mobilization studies.

Kishore K. Mohanty

2003-07-01

389

DILUTE SURFACTANT METHODS FOR CARBONATE FORMATIONS  

SciTech Connect

There are many carbonate reservoirs in US (and the world) with light oil and fracture pressure below its minimum miscibility pressure (or reservoir may be naturally fractured). Many carbonate reservoirs are naturally fractured. Waterflooding is effective in fractured reservoirs, if the formation is water-wet. Many fractured carbonate reservoirs, however, are mixed-wet and recoveries with conventional methods are low (less than 10%). Thermal and miscible tertiary recovery techniques are not effective in these reservoirs. Surfactant flooding (or huff-n-puff) is the only hope, yet it was developed for sandstone reservoirs in the past. The goal of this research is to evaluate dilute (hence relatively inexpensive) surfactant methods for carbonate formations and identify conditions under which they can be effective. We have conducted adsorption, phase behavior, interfacial tension (IFT) and wettability studies. Alfoterra-38 (0.05 wt%), Alfoterra-35 (0.05 wt%), SS-6656 (0.05 wt%), and DTAB (1 wt%) altered the wettability of the initially oil-wet calcite plate to an intermediate/water-wet state. Low IFT ({approx}10{sup -3} dynes/cm) is obtained with surfactants 5-166, Alfoterra-33 and Alfoterra-38. Plans for the next quarter include conducting wettability and mobilization studies.

Kishore K. Mohanty

2003-10-01

390

DILUTE SURFACTANT METHODS FOR CARBONATE FORMATIONS  

SciTech Connect

There are many carbonate reservoirs in US (and the world) with light oil and fracture pressure below its minimum miscibility pressure (or reservoir may be naturally fractured). Many carbonate reservoirs are naturally fractured. Waterflooding is effective in fractured reservoirs, if the formation is water-wet. Many fractured carbonate reservoirs, however, are mixed-wet and recoveries with conventional methods are low (less than 10%). Thermal and miscible tertiary recovery techniques are not effective in these reservoirs. Surfactant flooding (or huff-n-puff) is the only hope, yet it was developed for sandstone reservoirs in the past. The goal of this research is to evaluate dilute (hence relatively inexpensive) surfactant methods for carbonate formations and identify conditions under which they can be effective. We have conducted adsorption, phase behavior and wettability studies. Addition of Na{sub 2}CO{sub 3} decreases IFT with a minimum at about 0.2 M. Addition of surfactant decreases IFT further. In the absence of surfactant the minerals are oil wet after aging with crude oil. Addition of surfactant solution decreases the contact angle to intermediate wettability. Addition of Na{sub 2}CO{sub 3} decreases anionic surfactant adsorption on calcite surface. Plans for the next quarter include conducting adsorption, phase behavior and wettability studies.

Kishore K. Mohanty

2003-07-01

391

Dilute ferromagnetic semiconductors: Physics and spintronic structures  

NASA Astrophysics Data System (ADS)

This review compiles results of experimental and theoretical studies on thin films and quantum structures of semiconductors with randomly distributed Mn ions, which exhibit spintronic functionalities associated with collective ferromagnetic spin ordering. Properties of p-type Mn-containing III-V as well as II-VI, IV-VI, V2-VI3, I-II-V, and elemental group IV semiconductors are described, paying particular attention to the most thoroughly investigated system (Ga,Mn)As that supports the hole-mediated ferromagnetic order up to 190 K for the net concentration of Mn spins below 10%. Multilayer structures showing efficient spin injection and spin-related magnetotransport properties as well as enabling magnetization manipulation by strain, light, electric fields, and spin currents are presented together with their impact on metal spintronics. The challenging interplay between magnetic and electronic properties in topologically trivial and nontrivial systems is described, emphasizing the entangled roles of disorder and correlation at the carrier localization boundary. Finally, the case of dilute magnetic insulators is considered, such as (Ga,Mn)N, where low-temperature spin ordering is driven by short-ranged superexchange that is ferromagnetic for certain charge states of magnetic impurities.

Dietl, Tomasz; Ohno, Hideo

2014-01-01

392

Re-evaluating the 38th Parallel Serial Impact Hypothesis  

NASA Astrophysics Data System (ADS)

The idea that the 38th-parallel structures across Kansas, Missouri, and Illinois are serial impacts has been controversial. In addition to the original eight, two other structures are proximal to the 38th parallel, Dent Branch and Silver City Dome. Only Weaubleau, Decaturville, and Crooked Creek contain quartz grains with multiple directions of planar deformational features (PDFs). Shatter cones have been found at Decaturville and Crooked Creek. Key macroscopic observations of these impacts include: (1) circular outlines and notable central uplifts, (2) remarkably intense levels of structural deformation (folding, faulting, fracturing, and brecciation), (3) deformation dying out with depth and laterally away from the central uplift, and (4) associated igneous rocks only as clasts. From field and core studies and published reports, we consider other structures along the 38th parallel to be dubious (Hazelgreen), intrusive, (Hick's Dome), or volcanic in origin (Silver City Dome, Rose Dome, Furnace Creek, Dent Branch, and Avon). The age of the Weaubleau structure is constrained biostratigraphically as middle Mississippian (latest Osagean or early Meramecian). Crooked Creek and Decaturville are deeply eroded; their ages are poorly constrained. Crooked Creek contains isolated blocks of sandstone of late Osagean age, but the stratigraphic context of the blocks is poorly known. Other investigators contend the age of Decaturville is Pennsylvanian or Permian, based on CRM paleomagnetism and occurrence of an isolated sulfide breccia body in the central uplift. The Ozark plateau experienced Missouri Valley Type (MVT) sulfide mineralization during the Ouachita orogeny, but our examination of a sample from the sulfide breccia shows it is shattered pyrite and differs from typical MVT deposits. If the breccia is not associated with the regional mineralization, a middle Mississippian age cannot be excluded. Weaubleau, Decaturville, and Crooked Creek are aligned across 199 km. A line connecting the centers of the central uplifts of Weaubleau and Crooked Creek passes 1.5 km north of the center of Decaturville. Monte Carlo simulation was used to examine the probability that three temporally unrelated impacts could be aligned (±2° angular discordance) randomly over relatively short distances in an area that approximates the continental land surface. Modeling variables included number of impacts (N=200, N=300...N=1,000) and search radii (100-600 km). Twenty repetitions of 10,000 runs provided for analysis of standard deviation. For N=200 and radius of 100 km, an average of 6.6±2.5 aligned sets were found. For N=300, the results were 25.9±3.7, yielding a probability of P=0.003. Larger sample sizes and wider search radii produced more probable results, but given the number of known impacts (~175), it is highly improbable that Weaubleau, Decaturville, and Crooked Creek structures could be aligned but not temporally related. If Weaubleau, Decaturville, and Crooked Creek were products of a serial impact, they were not analogous with the Shoemaker-Levy 9 impacts on Jupiter, where planetary rotation affected the distribution, so the impacts would have occurred within seconds. In Mississippian paleogeographic reconstructions, the direction of impact would have been WSW-ENE, arguably along the ecliptic and near the equator. The distribution of deformation at Weaubleau suggests an oblique impact from present-day WSW-ENE, an argument against the serial impact hypothesis.

Evans, K. R.; Davis, G. H.; Miao, X.; Mickus, K. L.; Miller, J. F.; Morrow, J. R.

2008-12-01

393

Serial lung magnetic resonance imaging to monitor disease progression in a child with a diffuse alveolar hemorrhage syndrome.  

PubMed

Serial lung magnetic resonance imaging (MRI) was performed in a child with diffuse alveolar hemorrhage (DAH). To minimize radiation exposure with conventional serial chest computerized tomography (CT), serial MRIs of the lungs were used. This effectively monitored her disease process as well as detected acute hemorrhage after 5 years remission. PMID:25699125

Kaleel, Mohammed; Schramm, Craig; Pascal, Melanie; O'Louglin, Michael; Collins, Melanie Sue

2015-04-01

394

Serial Lung Magnetic Resonance Imaging to Monitor Disease Progression in a Child With a Diffuse Alveolar Hemorrhage Syndrome  

PubMed Central

Serial lung magnetic resonance imaging (MRI) was performed in a child with diffuse alveolar hemorrhage (DAH). To minimize radiation exposure with conventional serial chest computerized tomography (CT), serial MRIs of the lungs were used. This effectively monitored her disease process as well as detected acute hemorrhage after 5 years remission. PMID:25699125

Kaleel, Mohammed; Schramm, Craig; Pascal, Melanie; O’Louglin, Michael; Collins, Melanie Sue

2015-01-01

395

The role of serial bone mineral density testing for osteoporosis.  

PubMed

As a whole, groups of women who gain more bone mineral density (BMD) on antiresorptive medications experience greater fracture protection, although the relationship is not clear on the individual level. A literature search (Medline 1966 to present) for randomized, controlled trials was performed with keywords serial bone density, osteoporosis, dual-energy x-ray absorptiometry, fracture, alendronate, risedronate, calcitonin, estrogen replacement therapy, and raloxifene. Also, reference lists and tables of contents from journals were searched manually for additional relevant randomized controlled trials. Trials were 2-3 years in duration, and the number of subjects ranged from 670 to 3954. Medications analyzed include alendronate, either 5 mg/day or 5 mg/day, followed by 10 mg/day; raloxifene, 60 or 120 mg/day; and combination hormone replacement therapy (HRT) of four different regimen types. There have been no controlled studies showing that change in treatment based on serial bone density measurement results in improved patient outcomes. Whereas studies have shown changes in BMD during antiresorptive therapy to be predictive of fracture reduction in groups of patients, their utility in individual patients remains inconclusive. Osteoporotic women who lose BMD in the first year of alendronate or raloxifene use will likely gain BMD in the second year of treatment, illustrating regression to the mean. Effective medication for osteoporosis should not be changed solely because of BMD loss occurring after the first year of treatment. Young, healthy, postmenopausal women taking commonly prescribed doses of estrogen or estrogen/progestin (HRT) rarely lose BMD. Bone loss over the first 12 months of HRT is independent of bone loss in the next 24 months. If bone is not lost in the first 12 months of HRT, there is a significant chance that bone density will be lost later in treatment. Half of placebo-treated women do not lose BMD over 3 years. Treatment should be continued in patients who initially lose bone density on therapy because most will gain density with continued treatment and end in gaining bone overall. Also, patients who gain large amounts of bone in the first year and lose in the second year are not necessarily failing therapy but rather may be showing that a random error in the earlier bone density change corrects itself later. Loss of BMD with alendronate, raloxifene, or combination conjugated equine estrogen/ medroxyprogesterone acetate is likely to convert to gain in BMD. More research is needed to confirm that this regression to the mean may apply to all densitometry techniques, antiresorptives, age groups, and genders. PMID:11747684

Crandall, C

2001-11-01

396

Quantitative Serial MRI of the Treated Fibroid Uterus  

PubMed Central

Objective There are no long-term medical treatments for uterine fibroids, and non-invasive biomarkers are needed to evaluate novel therapeutic interventions. The aim of this study was to determine whether serial dynamic contrast-enhanced MRI (DCE-MRI) and magnetization transfer MRI (MT-MRI) are able to detect changes that accompany volume reduction in patients administered GnRH analogue drugs, a treatment which is known to reduce fibroid volume and perfusion. Our secondary aim was to determine whether rapid suppression of ovarian activity by combining GnRH agonist and antagonist therapies results in faster volume reduction. Methods Forty women were assessed for eligibility at gynaecology clinics in the region, of whom thirty premenopausal women scheduled for hysterectomy due to symptomatic fibroids were randomized to three groups, receiving (1) GnRH agonist (Goserelin), (2) GnRH agonist+GnRH antagonist (Goserelin and Cetrorelix) or (3) no treatment. Patients were monitored by serial structural, DCE-MRI and MT-MRI, as well as by ultrasound and serum oestradiol concentration measurements from enrolment to hysterectomy (approximately 3 months). Results A volumetric treatment effect assessed by structural MRI occurred by day 14 of treatment (9% median reduction versus 9% increase in untreated women; P?=?0.022) and persisted throughout. Reduced fibroid perfusion and permeability assessed by DCE-MRI occurred later and was demonstrable by 2–3 months (43% median reduction versus 20% increase respectively; P?=?0.0093). There was no apparent treatment effect by MT-MRI. Effective suppression of oestradiol was associated with early volume reduction at days 14 (P?=?0.041) and 28 (P?=?0.0061). Conclusion DCE-MRI is sensitive to the vascular changes thought to accompany successful GnRH analogue treatment of uterine fibroids and should be considered for use in future mechanism/efficacy studies of proposed fibroid drug therapies. GnRH antagonist administration does not appear to accelerate volume reduction, though our data do support the role of oestradiol suppression in GnRH analogue treatment of fibroids. Trial Registration ClinicalTrials.gov NCT00746031 PMID:24608161

Williams, Alistair R. W.; McKillop, Graham; Walker, Jane; Horne, Andrew W.; Newby, David E.; Anderson, Richard A.; Semple, Scott I.; Marshall, Ian; Lewis, Steff C.; Millar, Robert P.; Bastin, Mark E.; Critchley, Hilary O. D.

2014-01-01

397

Serial intervals of respiratory infectious diseases: a systematic review and analysis.  

PubMed

The serial interval of an infectious disease represents the duration between symptom onset of a primary case and symptom onset of its secondary cases. A good evidence base for such values is essential, because they allow investigators to identify epidemiologic links between cases and serve as an important parameter in epidemic transmission models used to design infection control strategies. We reviewed the literature for available data sets containing serial intervals and for reported values of serial intervals. We were able to collect data on outbreaks within households, which we reanalyzed to infer a mean serial interval using a common statistical method. We estimated the mean serial intervals for influenza A(H3N2) (2.2 days), pandemic influenza A(H1N1)pdm09 (2.8 days), respiratory syncytial virus (7.5 days), measles (11.7 days), varicella (14.0 days), smallpox (17.7 days), mumps (18.0 days), rubella (18.3 days), and pertussis (22.8 days). For varicella, we found an evidence-based value that deviates substantially from the 21 days commonly used in transmission models. This value of the serial interval for pertussis is, to the best of our knowledge, the first that is based on observations. Our review reveals that, for most infectious diseases, there is very limited evidence to support the serial intervals that are often cited. PMID:25294601

Vink, Margaretha Annelie; Bootsma, Martinus Christoffel Jozef; Wallinga, Jacco

2014-11-01

398

Natural born killers?: the development of the sexually sadistic serial killer.  

PubMed

Today's society seems enthralled with serial killers in the news and the media. Forensic psychiatrists often interview serial killers after they have been caught. There are retrospective studies and case reports of individuals who have committed sexually sadistic serial murders. However, there exists a dearth of case reports on adolescents who have expressed serious fantasies about becoming serial killer prior to actualizing their fantasy. This article presents nine clinical cases of 14- to 18-year-olds who have clinically significant fantasies of becoming a serial killer. Similarities exist in these adolescent cases when compared with retrospective studies and case reports of serial killers on the role of sexually sadistic fantasies and actual killings. Since it has been established that sexual paraphilias may develop at a young age, one can surmise that sadistic paraphilias may also develop in some adolescents. The question is posed, can we predict which of these adolescents may go on to actually become serial killers? This article focuses on how the sexually sadistic fantasy can eventually be acted out and possible motives for the act to be repeated multiple times. Finally, recommendations are made about assessing and treating a youngster who expresses violent sexually sadistic killing fantasies so that attempts can be made to interrupt the progression to actual killing. PMID:9323659

Johnson, B R; Becker, J V

1997-01-01

399

Exploiting Points-to Maps for De-/Serialization Code Generation  

SciTech Connect

Serialization code generators for C++ have restrictions on the implementation of dynamic arrays and void/function pointers. If the target program is not implemented with these restrictions, de- velopers have to manually change the source code to facilitate se- rialization code generation. Unfortunately, such changes hamper the benefits of code generation, and they are not localized. This pa- per presents the de-/serialization code generator Ser++ that does not restrict the implementation of these pointer types and, hence, eliminates the need to adapt the source code for serialization code generation. Ser++ can be considered an aspect weaver that i) traces the pointers, ii) identifies the statements in which properties regard- ing the serialization of pointer attributes can be extracted and, finally, iii) weaves the code to store these properties at runtime. It generates the de-/serialization functions in such a way that they serialize the pointer attributes according to the stored values of the properties. We have successfully used Ser++ to generate de- /serialization methods for a computer architecture and a power- flow simulator, without any modifications to the existing source code.

Ciraci, Selim; Villa, Oreste

2013-03-18

400

Statistical estimation of antibody concentration using multiple dilutions.  

PubMed

In medicine and chemistry, measurement of concentrations usually involves calibration that maps the observed responses to the underlying concentration using inversion of a standard curve. The Enzyme-linked ImmunoSorbent Assay (ELISA) is one example of such methods that is commonly used to measure antibody concentration. A problem in this and similar type of technology is that an accurate measurement is obtainable only if the observations fall within the optimal, near-linear range of the standard curve. It is common to conduct a series of doubling or tripling dilutions of the samples, so that at least some of the diluted samples are within the optimal range. A single dilution may then be selected for statistical analysis. This common practice does not fully utilize the data from multiple dilutions and reduces accuracy. We consider two weighted average estimators for fully utilizing the information from multiple dilutions. The first uses weights inversely proportional to the variances of the dilution-specific calibrated values; the second is a simplified form of the first. Simulation results demonstrated the superiority of this weighted estimation approach over the conventional approach of analyzing a single selected dilution. We apply the methods to an experimental study of malaria vaccine candidates. PMID:25585264

Cheung, Yin Bun; Xu, Ying; Remarque, Edmond J; Milligan, Paul

2015-02-01

401

40 CFR 1065.546 - Verification of minimum dilution ratio for PM batch sampling.  

Code of Federal Regulations, 2014 CFR

...Determine minimum dilution ratio based on molar flow data. This involves determination...measured intake air and dilute exhaust molar flow rates and the dilute exhaust chemical...You may alternatively estimate the molar raw exhaust flow rate based on...

2014-07-01

402

40 CFR 1065.546 - Validation of minimum dilution ratio for PM batch sampling.  

Code of Federal Regulations, 2012 CFR

...Determine minimum dilution ratio based on molar flow data. This involves determination...measured intake air and dilute exhaust molar flow rates and the dilute exhaust chemical...You may alternatively estimate the molar raw exhaust flow rate based on...

2012-07-01

403

40 CFR 1065.546 - Validation of minimum dilution ratio for PM batch sampling.  

Code of Federal Regulations, 2013 CFR

...Determine minimum dilution ratio based on molar flow data. This involves determination...measured intake air and dilute exhaust molar flow rates and the dilute exhaust chemical...You may alternatively estimate the molar raw exhaust flow rate based on...

2013-07-01

404

Dilute Oxygen Combustion Phase 2 Final Report  

SciTech Connect

A novel burner, in which fuel (natural gas) and oxidant (oxygen or air) are separately injected into a furnace, shows promise for achieving very low nitrogen oxide(s) (NOx) emissions for commercial furnace applications. The dilute oxygen combustion (DOC) burner achieves very low NOx through in-furnace dilution of the oxidant stream prior to combustion, resulting in low flame temperatures, thus inhibiting thermal NOx production. The results of a fundamental and applied research effort on the development of the DOC burner are presented. In addition, the results of a market survey detailing the potential commercial impact of the DOC system are disclosed. The fundamental aspects of the burner development project involved examining the flame characteristics of a natural gas turbulent jet in a high-temperature (~1366 K) oxidant (7-27% O2 vol. wet). Specifically, the mass entrainment rate, the flame lift-off height, the velocity field and major species field of the jet were evaluated as a function of surrounding-gas temperature and composition. The measured entrainment rate of the fuel jet decreased with increasing oxygen content in the surrounding high-temperature oxidant, and was well represented by the d+ scaling correlation found in the literature. The measured flame lift-off height decreased with increasing oxygen content and increasing temperature of the surrounding gas. An increase in surrounding-gas oxygen content and/or temperature inhibited the velocity decay within the jet periphery as a function of axial distance as compared to isothermal turbulent jets. However, the velocity measurements were only broadly represented by the d+ scaling correlation. Several DOC burner configurations were tested in a laboratory-scale furnace at a nominal firing rate of 185 kW (~0.63 MMBtu/h). The flue gas composition was recorded as a function of furnace nitrogen content, furnace temperature, burner geometric arrangement, firing rate, and fuel injection velocity. NOx emissions increased with increasing furnace nitrogen content and furnace temperature, but remained relatively insensitive to variations in fuel injection velocity and firing rate. NOx emissions below 5-10-3 g/MJ (10 ppm-air equivalent at 3% O2 dry) were obtained for furnace temperatures below 1533 K (2300?F) and furnace nitrogen levels between 1 and 40%. CO emissions were typically low (<35 ppm). Detailed in-furnace species measurements revealed the importance of the interior furnace circulation patterns, as influenced by fuel and oxidant injection schemes, on pollutant emissions. The combustion stability traits of several DOC burner arrangements were ascertained through furnace pressure measurements, wit6h increased stability occurring as furnace temperature increased and as the separation distance between fuel and oxidant inputs decreased. Based on current market conditions, oxy-fuel conversion of batch steel reheat furnaces with a DOC burner is justified on the basis of lower utility costs alone. However, conversion of continuous steel reheat furnaces, which are responsible for most steel production, required additional economic incentives, such as further fuel savings, increased furnace productivity, or emission credits.

Ryan, H.M.; Riley, M.F.; Kobayashi, H.

2005-09-30

405

Dilute Oxygen Combustion Phase I Final Report  

SciTech Connect

A novel burner, in which fuel (natural gas) and oxidant (oxygen or air) are separately injected into a furnace, shows promise for achieving very low nitrogen oxide(s) (NOx) emissions for commercial furnace applications. The dilute oxygen combustion (DOC) burner achieves very low NOx through in-furnace dilution of the oxidant stream prior to combustion, resulting in low flame temperatures, thus inhibiting thermal NOx production. The results of a fundamental and applied research effort on the development of the DOC burner are presented. In addition, the results of a market survey detailing the potential commercial impact of the DOC system are disclosed. The fundamental aspects of the burner development project involved examining the flame characteristics of a natural gas turbulent jet in a high-temperature (~1366 K) oxidant (7-27% O2 vol. wet). Specifically, the mass entrainment rate, the flame lift-off height, the velocity field and major species field of the jet were evaluated as a function of surrounding-gas temperature and composition. The measured entrainment rate of the fuel jet decreased with increasing oxygen content in the surrounding high-temperature oxidant, and was well represented by the d+ scaling correlation found in the literature. The measured flame lift-off height decreased with increasing oxygen content and increasing temperature of the surrounding gas. An increase in surrounding-gas oxygen content and/or temperature inhibited the velocity decay within the jet periphery as a function of axial distance as compared to isothermal turbulent jets. However, the velocity measurements were only broadly represented by the d+ scaling correlation. Several DOC burner configurations were tested in a laboratory-scale furnace at a nominal firing rate of 185 kW (~0.63 MMBtu/h). The flue gas composition was recorded as a function of furnace nitrogen content, furnace temperature, burner geometric arrangement, firing rate, and fuel injection velocity. NOx emissions increased with increasing furnace nitrogen content and furnace temperature, but remained relatively insensitive to variations in fuel injection velocity and firing rate. NOx emissions below 5-10-3 g/MJ (10 ppm-air equivalent at 3% O2 dry) were obtained for furnace temperatures below 1533 K (2300°F) and furnace nitrogen levels between 1 and 40%. CO emissions were typically low (<35 ppm). Detailed in-furnace species measurements revealed the importance of the interior furnace circulation patterns, as influenced by fuel and oxidant injection schemes, on pollutant emissions. The combustion stability traits of several DOC burner arrangements were ascertained through furnace pressure measurements, wit6h increased stability occurring as furnace temperature increased and as the separation distance between fuel and oxidant inputs decreased. Based on current market conditions, oxy-fuel conversion of batch steel reheat furnaces with a DOC burner is justified on the basis of lower utility costs alone. However, conversion of continuous steel reheat furnaces, which are responsible for most steel production, required additional economic incentives, such as further fuel savings, increased furnace productivity, or emission credits.

Ryan, H.M.; Riley, M.F.; Kobayashi, H.

1997-10-31

406

Dilute oxygen combustion. Phase I report  

SciTech Connect

A novel burner, in which fuel (natural gas) and oxidant (oxygen or air) are separately injected into a furnace, shows promise for achieving very low nitrogen oxide(s) (NO{sub x}) emissions for commercial furnace applications. The dilute oxygen combustion (DOC) burner achieves very low NO{sub x} through in-furnace dilution of the oxidant stream prior to combustion, resulting in low flame temperatures, thus inhibiting thermal NO{sub x} production. The results of a fundamental and applied research effort on the development of the DOC burner are presented. In addition, the results of a market survey detailing the potential commercial impact of the DOC system are disclosed. The fundamental aspects of the burner development project involved examining the flame characteristics of a natural gas turbulent jet in a high-temperature ({approximately}1366 K) oxidant (7-27% O{sub 2} vol. wet). Specifically, the mass entrainment rate, the flame lift-off height, the velocity field and major species field of the jet were evaluated as a function of surrounding-gas temperature and composition. The measured entrainment rate of the fuel jet decreased with increasing oxygen content in the surrounding high-temperature oxidant, and was well represented by the d{sup +} scaling correlation found in the literature. The measured flame lift-off height decreased with increasing oxygen content and increasing temperature of the surrounding gas. An increase in surrounding-gas oxygen content and/or temperature inhibited the velocity decay within the jet periphery as a function of axial distance as compared to isothermal turbulent jets. However, the velocity measurements were only broadly represented by the d{sup +} scaling correlation. Several DOC burner configurations were tested in a laboratory-scale furnace at a nominal firing rate of 185 kW ({approximately}0.63 MMBtu/h). The flue gas composition was recorded as a function of furnace nitrogen content, furnace temperature, burner geometric arrangement, firing rate, and fuel injection velocity. NO{sub x} emissions increased with increasing furnace nitrogen content and furnace temperature, but remained relatively insensitive to variations in fuel injection velocity and firing rate. NO{sub x} emissions below 5{times}10{sup -3} g/MJ (10 ppm-air equivalent at 3% O{sub 2} dry) were obtained for furnace temperatures below 1533 K (2300{degree}F) and furnace nitrogen levels between 1 and 40%. CO emissions were typically low (<35 ppm). Detailed in- furnace species measurements revealed the importance of the interior furnace circulation patterns, as influenced by fuel and oxidant injection schemes, on pollutant emissions. The combustion stability traits of several DOC burner arrangements were ascertained through furnace pressure measurements, with increased stability occurring as furnace temperature increased and as the separation distance between fuel and oxidant inputs decreased. Based on current market conditions, oxy-fuel conversion of batch steel reheat furnaces with a DOC burner is justified on the basis of utility costs alone. However, conversion of continuous steel reheat furnaces, which are responsible for most steel production, requires additional economic incentives, such as further fuel savings, increased furnace productivity, or emission credits.

NONE

1997-10-01

407

Enhanced electrohydrodynamic collapse of DNA due to dilute polymers.  

PubMed

We experimentally demonstrate that addition of small, charge-neutral polymers to a buffer solution can promote compression of dilute solutions of single electrophoresing DNA. This phenomenon contrasts with the observed extension of DNA during capillary electrophoresis in dilute solutions of high molecular weight polymers. We propose these discrepancies in micron-scale DNA configurations arise from different nano-scale DNA-polymer collision events, controlled by solute polymer properties. We build upon theories previously proposed for intermolecular DNA aggregation in polymer-free solutions to develop scaling theories that describe trends seen in our data for intramolecular DNA compaction in dilute polymer solutions. PMID:24926388

Benjamin Renner, C; Du, Ning; Doyle, Patrick S

2014-05-01

408

Effect of dilution on carboxymethylcellulase and xylanase assays  

SciTech Connect

It has been demonstrated that the dilution of samples prior to the carboxymethylcellulase and xylanase assays causes serious discrepancies in the numerical values obtained for the enzyme activities. Even when the sample is assayed with the identical procedure, one could obtain different numerical values of the enzyme activity U depending on how much this sample has been diluted before the enzyme assay. Two crude commercial cellulase samples of Aspergillus niger and Trichoderma viride as well as the culture filtrate of our newly isolated acidophilic fungus have been used for the demonstration. An empirical method for reporting the cellulolytic activity by taking into account this dilution effect is proposed.

Cauchon, N.; LeDuy, A.

1984-08-01

409

Two-stage dilute acid prehydrolysis of biomass  

DOEpatents

A two-stage dilute acid prehydrolysis process on xylan containing hemicellulose in biomass is effected by: treating feedstock of hemicellulosic material comprising xylan that is slow hydrolyzable and xylan that is fast hydrolyzable under predetermined low temperature conditions with a dilute acid for a residence time sufficient to hydrolyze the fast hydrolyzable xylan to xylose; removing said xylose from said fast hydrolyzable xylan and leaving a residue; and treating said residue having a slow hydrolyzable xylan with a dilute acid under predetermined high temperature conditions for a residence time required to hydrolyze said slow hydrolyzable xylan to xylose.

Grohmann, Karel (Winter Haven, FL); Torget, Robert W. (Littleton, CO)

1992-01-01

410

Bacterial survival in a dilute environment.  

PubMed Central

Bacteria were isolated from lake water, and their ability to remain viable in a dilute, nutrient-deficient environment was tested by a method that permits suspension of test bacteria between two appressed microporous membranes in an aqueous environment. This approach permitted separation of the lake isolates into two categories. Members of the tribe Klebsielleae were shown to have a prolonged survival rate of 40% or better after 24 h, whereas nonsurvivors were not viable for much longer than 24 h. These nonsurvivors belonged to the genera Acinetobacter, Aeromonas, Alcaligenes, Erwinia, Escherichia, Flavobacterium, and Pseudomonas. Differences in ribonuclease and adenosine triphosphatase levels between Escherichia coli (nonsurvivor) and Klebsiella (survivor) cells were detected. At pH 7.5, stressed E. coli cells contained 14% of the adenosine triphosphatase activity detected in the control, whereas at pH 5.5, in the presence of calcium ions, these same cells contained 50% of the control adenosine triphosphatase levels. At pH 7.2, E. coli cells were strongly inhibited by an adenosine triphosphatase inhibitor, bathophenanthroline (88%); oligomycin (64%); and the proton ionophore carbonyl- cyanide-m-chlorophenyl hydrazone (67%). Both sodium azide and valinomycin were only moderately inhibitory (15 and 28%, respectively). Although the ability to scavenge internal endogenous reserves seems important, we postulate that certain enteric bacteria are capable of utilizing acidic conditions (pH 5.5) as an electrochemical gradient to generate necessary high-energy intermediates for prolongation of survival beyond that possible in environments of near-neutraL pH. PMID:6454390

Sjogren, R E; Gibson, M J

1981-01-01

411

Ionic liquids behave as dilute electrolyte solutions.  

PubMed

We combine direct surface force measurements with thermodynamic arguments to demonstrate that pure ionic liquids are expected to behave as dilute weak electrolyte solutions, with typical effective dissociated ion concentrations of less than 0.1% at room temperature. We performed equilibrium force-distance measurements across the common ionic liquid 1-butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide ([C4mim][NTf2]) using a surface forces apparatus with in situ electrochemical control and quantitatively modeled these measurements using the van der Waals and electrostatic double-layer forces of the Derjaguin-Landau-Verwey-Overbeek theory with an additive repulsive steric (entropic) ion-surface binding force. Our results indicate that ionic liquids screen charged surfaces through the formation of both bound (Stern) and diffuse electric double layers, where the diffuse double layer is comprised of effectively dissociated ionic liquid ions. Additionally, we used the energetics of thermally dissociating ions in a dielectric medium to quantitatively predict the equilibrium for the effective dissociation reaction of [C4mim][NTf2] ions, in excellent agreement with the measured Debye length. Our results clearly demonstrate that, outside of the bound double layer, most of the ions in [C4mim][NTf2] are not effectively dissociated and thus do not contribute to electrostatic screening. We also provide a general, molecular-scale framework for designing ionic liquids with significantly increased dissociated charge densities via judiciously balancing ion pair interactions with bulk dielectric properties. Our results clear up several inconsistencies that have hampered scientific progress in this important area and guide the rational design of unique, high-free-ion density ionic liquids and ionic liquid blends. PMID:23716690

Gebbie, Matthew A; Valtiner, Markus; Banquy, Xavier; Fox, Eric T; Henderson, Wesley A; Israelachvili, Jacob N

2013-06-11

412

Development of gallium arsenide high-speed, low-power serial parallel interface modules: Executive summary  

NASA Technical Reports Server (NTRS)

Final report to NASA LeRC on the development of gallium arsenide (GaAS) high-speed, low power serial/parallel interface modules. The report discusses the development and test of a family of 16, 32 and 64 bit parallel to serial and serial to parallel integrated circuits using a self aligned gate MESFET technology developed at the Honeywell Sensors and Signal Processing Laboratory. Lab testing demonstrated 1.3 GHz clock rates at a power of 300 mW. This work was accomplished under contract number NAS3-24676.

1988-01-01

413

The Serial Engagement Model 17?Years After: From TCR Triggering to Immunotherapy  

PubMed Central

More than 15?years ago the serial engagement model was proposed as an attempt to solve the low affinity/high sensitivity paradox of TCR antigen recognition. Since then, the model has undergone ups and downs marked by the technical and conceptual advancements made in the field of T lymphocyte activation. Here, I describe the development of the model and survey recent literature providing evidence either for or against the idea that serial TCR/pMHC engagement might contribute to T lymphocyte activation. I also discuss how the concept of serial TCR engagement might be useful in the design of immunotherapeutic approaches aimed at potentiating T lymphocyte responses in vivo. PMID:22973273

Valitutti, Salvatore

2012-01-01

414

The Serial Engagement Model 17?Years After: From TCR Triggering to Immunotherapy.  

PubMed

More than 15?years ago the serial engagement model was proposed as an attempt to solve the low affinity/high sensitivity paradox of TCR antigen recognition. Since then, the model has undergone ups and downs marked by the technical and conceptual advancements made in the field of T lymphocyte activation. Here, I describe the development of the model and survey recent literature providing evidence either for or against the idea that serial TCR/pMHC engagement might contribute to T lymphocyte activation. I also discuss how the concept of serial TCR engagement might be useful in the design of immunotherapeutic approaches aimed at potentiating T lymphocyte responses in vivo. PMID:22973273

Valitutti, Salvatore

2012-01-01

415

Dominance of the odometer over serial landmark learning in honeybee navigation  

NASA Astrophysics Data System (ADS)

Honeybees use their visual flow field to measure flight distance. It has been suggested that the experience of serial landmarks encountered on the flight toward a feeding place contributes to distance estimation. Here, we address this question by tracing the flight paths of individual bees with a harmonic radar system. Bees were trained along an array of three landmarks (tents), and the distance between these landmarks was either increased or decreased under two test conditions. We find that absolute distance estimation dominates the search for the feeding place, but serial position effects are also found. In the latter case, bees search only or additionally at locations determined by serial experience of the landmarks.

Menzel, Randolf; Fuchs, Jacqueline; Nadler, Leonard; Weiss, Benjamin; Kumbischinski, Nicole; Adebiyi, Daniel; Hartfil, Sergej; Greggers, Uwe

2010-08-01

416

Destructive hostility: the Jeffrey Dahmer case. A psychiatric and forensic study of a serial killer.  

PubMed

We were involved as forensic experts in the case of the serial killer Jeffrey Dahmer. We discuss the scene and victim autopsy findings, with a brief consideration of the basic emotion of hostility. These findings support the thesis that at the basis of this serial killer's behavior were primary unconscious feelings of hate that he had channeled into a sadistic programmed destruction of 17 young men. The interview of the serial killer, the photographic scene documentation, and the autopsy findings stress the ambivalent homosexuality of the killer, his sexual sadism, his obsessive fetishism, and his possible cannibalism and necrophilia. PMID:7879770

Jentzen, J; Palermo, G; Johnson, L T; Ho, K C; Stormo, K A; Teggatz, J

1994-12-01

417

Articulated rigid registration for serial lower-limb mouse imaging.  

PubMed

This paper describes a new piecewise rotational transformation model for capturing the articulation of joints such as the hip and the knee. While a simple piecewise rigid model can be applied, such models suffer from discontinuities at the motion boundary leading to both folding and stretching. Our model avoids both of these problems by constructing a provably continuous transformation along the motion interface. We embed this transformation model within the robust point matching framework and demonstrate its successful application to both synthetic data, and to serial x-ray CT mouse images. In the later case, our model captures the articulation of six joints, namely the left/right hip, the left/right knee and the left/right ankle. In the future such a model could be used to initialize non-rigid registrations of images from different subjects, as well as, be embedded in intensity-based and integrated registration algorithms. It could also be applied to human data in cases where articulated motion is an issue (e.g. image guided prostate radiotherapy, lower extremity CT angiography). PMID:16686048

Papademetris, Xenophon; Dione, Donald P; Dobrucki, Lawrence W; Staib, Lawrence H; Sinusas, Albert J

2005-01-01

418

Histopathology of serial graft biopsies from liver transplant recipients.  

PubMed Central

Serial graft biopsies (n = 78) from 12 liver transplant recipients (followed clinically up to 47 months) were studied with the use of histology, histochemistry, immunostaining, and electron microscopy. Planned-protocol needle biopsy specimens were taken from the graft before removal from the donor, 1 hour after transplantation, on the eighth day, and at yearly intervals. Nonprotocol biopsies were taken when deterioration of the clinical condition made a decision on changes in the regimen necessary. The protocol biopsies provided a baseline for graft condition and diagnostic histopathologic features. In these biopsies signs of hyperacute rejection, chronic rejection, or the recipient's previous liver disease were not observed. Mild acute rejection was regularly present on the eighth day, possibly due to a lag phase in the effect of immunosuppression. The syndromes in the nonprotocol biopsies included "pure" parenchymal cholestasis, reversible acute rejection resembling chronic active hepatitis, viral infection, and acute bacterial cholangitis. Each of these syndromes correlated with a separate histopathologic entity. Therefore, these entities proved to be of diagnostic value. It is concluded that a graft biopsy may substantially add to the pathogenetic interpretation, differential diagnosis, and management of major graft syndromes in orthotopic liver transplant recipients. Images Figure 5 Figure 1 Figure 2 Figure 3 Figure 4 PMID:6362423

Eggink, H. F.; Hofstee, N.; Gips, C. H.; Krom, R. A.; Houthoff, H. J.

1984-01-01

419

Serial exercise gated radionuclide ventriculograms (RVG) in monitoring doxorubicin cardiotoxicity  

SciTech Connect

The resting RVG (Radionuclide Ventriculograms) are demonstrated to be an effective monitor of the cardiotoxicity of doxorubicin. The exercise RVG has not been as well studied to see if it yields additional information or detects toxicity effects earlier. Sixteen patients receiving doxorubicin for chemotherapy had 2-6 serial exercise studies with intervals between studies of 1 month to 15 months. The patients exercised varying amounts with cardiac work indicated by their double products (HR x Sys. BP). Although all patients started with a normal resting LVEF (>50%), 5 of the 16 did not have a normal response (greater than or equal to5% increase in LVEF) with initial exercise study. Of the 11 patients with an initially normal response to exercise, on at least one subsequent study, 3 had an abnormal response to exercise. On a later follow up study 1 of these 3 patients again had a normal response to exercise. Six of these 11 patients had had RVG evidence of cardiotoxicity. Four of these 6 patients had continually normal exercise responses, while 2 of these 5 patients had had an abnormal exercise response. An initial exercise RVG may be reasonable to detect unsuspected CAD in cancer victims. These patients are reported to be more sensitive to the toxic effects of doxorubicin. Follow up exercise RVGs do not contribute useful information, do not predict cardiotoxicity, and may be misleading.

Goldstein, H.A.; Lahoda, J.; Fox, L.

1985-05-01

420

Serial characterisation of monocyte and neutrophil function after lung resection  

PubMed Central

Objectives The primary aim of this prospective study was to perform a comprehensive serial characterisation of monocyte and neutrophil function, circulating monocyte subsets, and bronchoalveolar lavage (BAL) fluid after lung resection. A secondary aim was to perform a pilot, hypothesis-generating evaluation of whether innate immune parameters were associated with postoperative pneumonia. Methods Forty patients undergoing lung resection were studied in detail. Blood monocytes and neutrophils were isolated preoperatively and at 6, 24 and 48?h postoperatively. BAL was performed preoperatively and immediately postoperatively. Monocyte subsets, monocyte responsiveness to lipopolysaccharide (LPS) and neutrophil phagocytic capacity were quantified at all time points. Differential cell count, protein and cytokine concentrations were measured in BAL. Pneumonia evaluation at 72?h was assessed using predefined criteria. Results After surgery, circulating subsets of classical and intermediate monocytes increased significantly. LPS-induced release of proinflammatory cytokines from monocytes increased significantly and by 48?h a more proinflammatory profile was found. Neutrophil phagocytosis demonstrated a small but significant fall. Factors associated with postoperative pneumonia were: increased release of specific proinflammatory and anti-inflammatory cytokines from monocytes; preoperative neutrophilia; and preoperative BAL cell count. Conclusions We conclude that postoperative lung inflammation is associated with specific changes in the cellular innate immune response, a better understanding of which may improve patient selection and prediction of complications in the future. PMID:25478189

Jones, Richard O; Brittan, Mairi; Anderson, Niall H; Conway Morris, Andrew; Murchison, John T; Walker, William S; Simpson, A John

2014-01-01

421

Three-dimensional reconstruction from serial sections using triakis  

NASA Astrophysics Data System (ADS)

Various methods for serial-section reconstruction from images of tissue sections have been investigated using the Apple Macintosh-based program Triakis. Triakis is a three-dimensional mathematical morphology software package that processes 3-D binary data in the FCC (face centered cubic) tessellation by means of LUT (look-up table) manipulations. Tissue sections have been obtained from a breast tumor and traced using PC3-D [Jandel Scientific, Corte Madera, Calif.] were transferred via a software interface to Triakis. Triakis uses the Apple Macintosh polygon filling routine to fill each tracing with binary ones. Next, ranking transforms in the binary FCC tessellation were used in order to demonstrate their capability of smoothly interpolating from one section to the other. The optimum transform is based on the placement of the binarized tissue sections in hexagonal planes and uses three cycles of a rank three transform for the initial interpolation. Irregularities are then removed from the resulting solid by seven cycles of a compound transform. Thereafter, the filled polygons were eroded using Triakis and, from the annular histogram, the spatial interrelationships of malignant cells within the tumor determined.

Preston, Kendall, Jr.; Siderits, Richard

1992-06-01

422

Phonological and semantic strategies in immediate serial recall.  

PubMed

It has been suggested that certain theoretically important anomalous results in the area of verbal short-term memory could be attributable to differences in strategy. However there are relatively few studies that investigate strategy directly. We describe four experiments, each involving the immediate serial recall of word sequences under baseline control conditions, or preceded by instruction to use a phonological or semantic strategy. Two experiments varied phonological similarity at a presentation rate of one item every 1 or 2 seconds. Both the control and the phonologically instructed group showed clear effects of similarity at both presentation rates, whereas these were largely absent under semantic encoding conditions. Two further experiments manipulated word length at the same two rates. The phonologically instructed groups showed clear effects at both rates, the control group showed a clear effect at the rapid rate which diminished with the slower presentation, while the semantically instructed group showed a relatively weak effect at the rate of one item per second, and a significant reverse effect with slower presentation. The latter finding is interpreted in terms of fortuitous differences in inter-item rated associability between the two otherwise matched word pools, reinforcing our conclusion that the semantically instructed group were indeed encoding semantically. Implications for controlling strategy by instruction are discussed. PMID:18432478

Campoy, Guillermo; Baddeley, Alan

2008-05-01

423

Redintegration, task difficulty, and immediate serial recall tasks.  

PubMed

While current theoretical models remain somewhat inconclusive in their explanation of short-term memory (STM), many theories suggest at least a contribution of long-term memory (LTM) to the short-term system. A number of researchers refer to this process as redintegration (e.g., Schweickert, 1993). Under short-term recall conditions, the current study investigated the effects of redintegration and task difficulty in order to extend research conducted by Neale and Tehan (2007). Thirty participants in Experiment 1 and 26 participants in Experiment 2 completed a serial recall task in which retention interval, presentation rate, and articulatory suppression were used to modify task difficulty. Redintegration was examined by manipulating the characteristics of the to-be-remembered items; lexicality in Experiment 1 and wordlikeness in Experiment 2. Responses were scored based on correct-in-position recall, item scoring, and order accuracy scoring. In line with the Neale and Tehan results, as the difficulty of the task increased so did the effects of redintegration. This was evident in that the advantage for words in Experiment 1 and wordlikeness in Experiment 2 decreased as task difficulty increased. This relationship was observed for item but not order memory, and findings were discussed in relation to the theory of redintegration. (PsycINFO Database Record (c) 2015 APA, all rights reserved). PMID:25730640

Ritchie, Gabrielle; Tolan, Georgina Anne; Tehan, Gerald

2015-03-01

424

A rare case of serial killing by poisoning.  

PubMed

A case of serial killing by poisoning by a 59-year-old practical nurse is discussed. Following a report by an emergency-room doctor of an attempted murder, police performed an investigation into all deaths of patients in the nurse's care. Earlier, a medico-legal cause-of-death investigation had been performed on two of these cadavers, but in the other three cases the death certificate had been issued after a medical investigation only. In two of these latter cases, the body had been cremated, but fixed histological samples taken at medical autopsy were available, while in one case the person had died recently and the body was thereafter exhumed and autopsied. All of the suspected victims were older people who required nursing, and the nurse's course of action was consistent in all cases. In the absence of ordinary post-mortem toxicology samples in the medical cases, extraordinary evidence--paraffin-embedded liver tissue samples originally taken for histology at autopsy--was successfully recovered in two cases and analyzed for drugs. In all five cases, drugs not prescribed to the patient were detected, including digoxin, dixyrazine, citalopram, venlafaxine, and benzodiazepines (diazepam, chlordiazepoxide, temazepam, and oxazepam). The nurse was eventually found guilty of five murders by poisoning, five attempted murders, and three aggravated assaults. The nurse was sentenced to life imprisonment. PMID:23613335

Vuori, Erkki; Pelander, Anna; Rasanen, Ilpo; Juote, Mikko; Ojanperä, Ilkka

2013-01-01

425

[Serial MRI findings in patients with CNS cryptococcosis].  

PubMed

We reported the serial magnetic resonance imaging (MRI) findings of two patients with central nervous system (CNS) cryptococcal infection without AIDS. The diagnosis of CNS cryptococcosis was made by visualizing the fungi in the CSF with the India ink test, detecting cryptococcal antigens, and culturing the fungus. Both patients had dilated perivascular Virchow-Robin (V-R) spaces, which were defined as small rounded lesions greater less than 3mm diameter that were hyperintense on T2-weighted images. They were present in the basal ganglia, brainstem and cerebral white matter. Case 1 had bilateral parietal arachnoid cyst which was thought to represent a focal collection of organisms and mucoid material within subarachnoid space. Abnormal optochiasmatic arachnoid enhancement detected in case 2, who had complete loss of vision. With disease progression perivascular V-R increased in size, resulting in the developing cryptococomas which were defined as rounded lesions greater than 3mm diameter, and were hyperintense on T2-weighted images in the basal ganglia, cerebellum and cerebral white matter. In follow-up MRI of those patients, radiological progression was seen despite appropriate treatment and falling CSF cryptococcal antigens. In conclusion, this spectrum of MRI appearances in CNS cryptococcosis reflects the pathological mechanism of invasion by the fungus, and may be relatively specific for cryptococcosis. PMID:10078036

Kumazawa, K; Yamada, T; Nakamori, T; Hoshino, A; Terao, S; Mitsuma, T

1998-09-01

426

Serial analysis of gene expression in a microglial cell line.  

PubMed

We used the serial analysis of gene expression (SAGE) method to systematically analyze transcripts present in a microglial cell line. Over 10,000 SAGE tags were sequenced, and shown to represent 6,013 unique transcripts. Among the diverse transcripts that had not been previously detected in microglia were those for cytokines such as endothelial monocyte-activating polypeptide I (EMAP I), and for cell surface antigens, including adhesion molecules such as CD9, CD53, CD107a, CD147, CD162 and mast cell high affinity IgE receptor. In addition, we detected transcripts that were characteristic of hematopoietic cells or mesodermal structures, such as E3 protein, A1, EN-7, B94, and ufo. Furthermore, the profile contained a transcript, Hn1, that is important in hematopoietic cells and neurological development (Tang et al. Mamm Genome 8:695-696, 1997), suggesting the probable neural differentiation of microglia from the hematopoietic system in development. Messenger RNA expression of these genes was confirmed by RT-PCR in primary cultures of microglia. Significantly, this is the first systematic profiling of the genes expressed in a microglial cell line. The identification and further characterization of the genes described here should provide potential new targets for the study of microglial biology. PMID:10559785

Inoue, H; Sawada, M; Ryo, A; Tanahashi, H; Wakatsuki, T; Hada, A; Kondoh, N; Nakagaki, K; Takahashi, K; Suzumura, A; Yamamoto, M; Tabira, T

1999-12-01

427

Serial reproduction of traumatic events: does the chain unravel?  

PubMed

Our goal in this paper is to show that a careful analysis of recall accuracy within a serial reproduction chain can add to a detailed qualitative analysis of the reproductions within the chain. The texts we chose are based on newspaper reports concerning current events, which are far from being mundane: reports of tragic events, even traumatic events. The participants were 216 students who were randomly assigned to 54 four-person reproduction chains, 18 for each of three 160-word texts. The reproduction chain is highly dependent on the recall accuracy of the first generation (i.e., the first participant in the reproduction chain). Thus, we argue (and show) that there should be a qualitative difference between chains starting off with a high level of recall accuracy from those starting off with a low level of recall accuracy. Our data-analytic approach is based on trend analysis, which we argue is an apt quantitative, holistic, dynamic, process-oriented type of analysis that is required in such research. PMID:25168856

Nahari, Galit; Sheinfeld, Vallery; Glicksohn, Joseph; Nachson, Israel

2015-02-01

428

High speed serial link for UA1 microprocessor network  

E-print Network

The UA1 data acquisition system consists of a set of distributed microprocessor units. An interprocessor link, independent of the CAMAC data readout, has been developed in order to have continuous remote control and run-time data handling, e.g. transmission of calibration programs/parameters, equipment test/status and histogram accumulation. The data transmission system is designed to be used in a loop configuration equipped with transceivers for twisted pair cables (RS-422). As an economical system, it is running as an ancillary serial loop-link between microprocessors, like Data Acquisition Crate Controllers and systems with distributed intelligence. The software driver consists of a loop-controller package, which may run in a BAMBI Computer Language environment and a fully interrupt controlled program for all other secondary stations. A special single-character mode provides a handy link for remote debugging in a pseudo-full-duplex mode. The format is based on the HDLC protocol without sequence numbering. ...

Cittolin, S; Zurfluh, E

1981-01-01

429

Serially connected solid oxide fuel cells having monolithic cores  

DOEpatents

Disclosed is a solid oxide fuel cell for electrochemically combining fuel and oxidant for generating galvanic output. The cell core has an array of cell segments electrically serially connected in the flow direction, each segment consisting of electrolyte walls and interconnect that are substantially devoid of any composite inert materials for support. Instead, the core is monolithic, where each electrolyte wall consists of thin layers of cathode and anode materials sandwiching a thin layer of electrolyte material therebetween. Means direct the fuel to the anode-exposed core passageways and means direct the oxidant to the cathode-exposed core passageways; and means also direct the galvanic output to an exterior circuit. Each layer of the electrolyte composite materials is of the order of 0.002 to 0.01 cm thick; and each layer of the cathode and anode materials is of the order of 0.002 to 0.05 cm thick. Between 2 and 50 cell segments may be connected in series.

Herceg, J.E.

1985-05-20

430

Automated serial sectioning applied to 3D paper structure analysis.  

PubMed

A better understanding of paper properties requires a detailed knowledge about the spatial arrangement of its constituent materials in its structure. This paper presents a novel approach for the analysis of the three-dimensional paper structure at the fibre level. A technique combining a rotary microtome and an optical microscopy was developed allowing serial sectioning of hundreds of cuts. The microscope is fixed on a moveable stage and mounted in front of a microtome. Repeatedly, thin slices are cut off an embedded paper sample and the cut block surface is scanned in a fully automated process. The prototype built is able to digitize paper samples with a size of more than 1 cm(2) at a possible three-dimensional resolution below 1 ?m. Advanced computer vision methods are applied to extract relevant information from the digitized samples. Currently, the most important applications are the analysis of pigment coating layers on the paper surfaces and the analysis of fibre transverse morphology. Besides the analysis of paper structures, this technique is also suited for the spatial analysis of other materials, if the structural features are accessible with light optical microscopy. PMID:21118393

Wiltsche, M; Donoser, M; Kritzinger, J; Bauer, W

2011-05-01

431

Ultrastructural reconstruction of Taenia ovis oncospheres from serial sections.  

PubMed

The cellular organisation of Taenia ovis oncospheres is interpreted from ultrathin serial sections and transmission electron microscopy following high pressure freezing and freeze-substitution. The surface of a hatched, non-activated T. ovis oncosphere is covered by an oncospheral membrane below which is the tegument bearing microvilli. The basal lamina of the tegument is underlain by broad bands of peripheral somatic musculature. Three pairs of hooks and associated muscles are present in the somatophoric third of the oncosphere. Approximately 19 cells of seven different types were identified which include: (i) a quadri-nucleated syncytium of penetration gland type 1 containing two lateral pairs of cell bodies interconnected by narrow cytoplasmic bridges (PG1); (ii) a quadri-nucleated syncytium of penetration gland type 2 (PG2); (iii) a single-nucleated median mesophoric gland cell; (iv) 10 somatic cells; (v) two germinative cells; (vi) two nerve cells; and (vii) a pair of median somatophoric cells. This study provides a clear understanding of the morphology of T. ovis oncospheres and forms the basis for further investigations into the biology of taeniid oncospheres. PMID:20478311

Jabbar, Abdul; Crawford, Simon; M?ocicki, Daniel; Swiderski, Zdzis?aw P; Conn, David B; Jones, Malcolm K; Beveridge, Ian; Lightowlers, Marshall W

2010-10-01

432

Retroviral sequences located within an intron of the dilute gene alter dilute expression in a tissue-specific manner.  

PubMed Central

The murine dilute coat color locus encodes an unconventional myosin heavy chain that is thought to be required for the elaboration or maintenance of dendrites or organelle transport in melanocytes and neurons. In previous studies we showed that the d mutation carried by many inbred strains of mice (now referred to as dilute viral, dv), is caused by the integration of an ecotropic murine leukemia virus (Emv-3) into the dilute gene and that phenotypic revertants of dv (termed d+) result from viral excision; a solo viral long terminal repeat (LTR) is all that remains in revertant DNA. In the studies described here we show that Emv-3 sequences are located within an intron of the dilute gene in a region of the C-terminal tail that is differentially spliced. We also show that these Emv-3 sequences result in the production of shortened and abnormally spliced dilute transcripts and that the level of this effect varies among tissues. This tissue-specific effect on dilute expression likely accounts for the absence of neurological abnormalities observed in dv mice. Surprisingly, we also found that the solo viral LTR present in revertant d+ DNA produces a tissue-specific effect on dilute expression, although this effect is less dramatic than with the full-length provirus and produces no obvious mutant phenotype. These findings have important implications for understanding the effects of viral sequences on mammalian gene expression. Images PMID:7774591

Seperack, P K; Mercer, J A; Strobel, M C; Copeland, N G; Jenkins, N A

1995-01-01

433

Determination of irritant threshold concentrations to weeds, trees and grasses through serial dilutions in intradermal testing on healthy clinically nonallergic dogs.  

PubMed

Irritant threshold concentration (ITC) for intradermal testing (IDT) was determined in 31 healthy, clinically nonallergic dogs. Twenty-three allergens were tested at five variable concentrations ranging from 1000 to 8000 PNU/mL. To distinguish irritant reactions from subclinical IgE-mediated hypersensitivities, serum allergy testing was performed. ITCs were determined by evaluating the lowest concentration to which no dogs (0% cut-off) and to which at least 10% of dogs (> or = 10% cut-off) reacted. ITCs at the 0% cut-off were: 1000 PNU/mL (Johnson grass), 2000 PNU/mL (Ash, Lamb's Quarter and Bermuda), 3000 PNU/mL (Bahia, Rye, Pig Weed and Virginia Oak), 4000 PNU/mL (Marsh Elder and Maple), 5000 PNU/mL (Sorrel sheep) and 7000 PNU/mL (Cocklebur and Black Willow). ITC for Dog Fennel, Box Elder and Red Cedar was <1000 PNU/mL. ITCs at the > or = 10% cut-off were: 2500 PNU/mL (Johnson), 3000 PNU/mL (Box Elder), 5000 PNU/mL (Bahia), 6000 PNU/mL (Pigweed and Marsh Elder) and 8000 PNU/mL (Virginia Oak and Black Willow). For all other allergens, the ITC was >8000 PNU/mL and could not be determined. No significant agreement between positive values was found for the same allergen on IDT and serum allergy testing for each dog suggesting reactions caused by the determined ITCs are less likely subclinical IgE-mediated reactions. These results suggest that ITCs may vary, also they may be very high for the allergens tested and that higher test concentrations may be used for IDT for the tested allergens without inducing an irritant reaction. Further studies are needed to evaluate the benefit of higher IDT concentrations in atopic dogs. PMID:20230589

Bauer, Cynthia L; Hensel, Patrick; Austel, Michaela; Keys, Deborah

2010-04-01

434

A Two-Fold Unveiling: Unmasking Classism in Group Work  

ERIC Educational Resources Information Center

The pervasive myth of the United States as a "classless society" silences the reality of social class oppression in this country. This silencing has received little attention to date in group work training, research, and practice. Unmasking classism may generate anxiety for group workers and members alike, yet holds potential for significant…

Newton, Kathryn

2010-01-01

435

Separation processes using expulsion from dilute supercritical solutions  

DOEpatents

A process is described for separating isotopes as well as other mixtures by utilizing the behavior of dilute repulsive or weakly attractive elements of the mixtures as the critical point of the solvent is approached.

Cochran, H.D. Jr.

1993-04-20

436

Fully portable, highly flexible dilution refrigerator systems for neutron scattering  

E-print Network

775 Fully portable, highly flexible dilution refrigerator systems for neutron scattering P. A systems developed specifically for neutron scattering environ- ments. The refrigerators are completely relatively recently however, the lowest temperatures available in almost all neutron scattering laboratories

Boyer, Edmond

437

Contraction/expansion flow of dilute elastic solutions in microchannels  

E-print Network

An experimental study is conducted on the nature of extensional flows of mobile dilute polymer solutions in microchannel. By observing such fluids on the microscale it is possible to generate large strain rates ([approximately] ...

Scott, Timothy Peter, 1980-

2004-01-01

438

Separation processes using expulsion from dilute supercritical solutions  

DOEpatents

A process for separating isotopes as well as other mixtures by utilizing the behavior of dilute repulsive or weakly attractive elements of the mixtures as the critical point of the solvent is approached.

Cochran, Jr., Henry D. (Oak Ridge, TN)

1993-01-01

439

Translation of dilution tolerance for gasoline SI engine  

E-print Network

There are a variety of fuel improvement strategies being developed for spark ignition engines which use dilution. Many of these technologies use a combination of different diluents. It is impractical in optimizing these ...

Niekamp, Troy S. (Troy Steven)

2013-01-01

440

Diluted tributyl phosphate as an extraetant for silver  

Microsoft Academic Search

Summary A new method is devised for the rapid solvent extraction of silver with diluted tributyl phosphate. Thus 40% TBP in butanol quantitatively extracts silver (49.8µg) from 1M nitric acid that is 2M in lithium nitrate as salting-out agent. Silver is stripped with dilute ammonia and is determined photometrically at 495 ran as its red-violet complex withp-diethylaminobenzylidenerhodanine. The effect of

A. A. Yadav; S. M. Khopkar

1971-01-01

441

Anatomy of symmetry energy of dilute nuclear matter  

E-print Network

The symmetry energy coefficients of dilute clusterized nuclear matter are evaluated in the $S$-matrix framework. Employing a few different definitions commonly used in the literature for uniform nuclear matter, it is seen that the different definitions lead to perceptibly different results for the symmetry coefficients for dilute nuclear matter. They are found to be higher compared to those obtained for uniform matter in the low density domain. The calculated results are in reasonable consonance with those extracted recently from experimental data.

J. N. De; S. K. Samaddar; B. K. Agrawal

2010-09-23

442

Integration of carbon nanotubes into diluted magnetic semiconductor  

Microsoft Academic Search

Carbon nanotubes (CNTs) were grown using catalytic pyrolysis of acetylene on a thin-film-diluted magnetic semiconductor (Co-8 at. % doped TiO2) without consuming the host layer of semiconductor TiO2. Effects of the thickness of the diluted magnetic semiconductor layer and the stacking structure on the growth of the carbon nanotubes were examined. The external diameter and crystalline structure of the nanotubes

Yun-Hi Lee; J. M. Yoo; J. Ah Lee; S. Y. Ahn; J. Joo; S. Lee; D. H. Kim; B. K. Ju; K. J. Song

2005-01-01

443

Stabilization of Diluted Aqueous Solutions of Horseradish Peroxidase  

Microsoft Academic Search

Effects of pH, enzyme concentration, and various supplements on the catalytic activity, temperature stability, and secondary structure of horseradish peroxidase (HRP) were studied in diluted aqueous solutions. In 5.0 mM citrate-phosphate buffer (pH 4.2) at 55°C and infinite dilution, HRP was inactivated with a rate constant of 2.86 × 10–3 s–1. CaCl2, BSA, and glycerol caused protective effects, whereas KCl,

A. N. Eremin; L. P. Budnikova; O. V. Sviridov; D. I. Metelitsa

2002-01-01

444

Site dilution of quantum spins in the honeycomb lattice  

Microsoft Academic Search

We consider the effect of random site dilution on a honeycomb lattice of quantum spins described by the antiferromagnetic Heisenberg spin- S model. Using linear spin-wave theory, we compute the zero-temperature magnetization and density of states as a function of dilution up to the classical percolation threshold. Several subtle issues regarding the treatment of quasidivergent zero-energy modes, which appear in

Eduardo V. Castro; N. M. R. Peres; K. S. D. Beach; Anders W. Sandvik

2006-01-01

445

Site dilution of quantum spins in the honeycomb lattice  

Microsoft Academic Search

We discuss the effect of site dilution on both the magnetization and the density of states of quantum spins in the honeycomb lattice, described by the antiferromagnetic Heisenberg spin-S model. Since the disorder introduced by the dilution process breaks translational invariance, the model has to be solved in real space. For this purpose a real-space Bogoliubov-Valatin transformation is used. In

Eduardo V. Castro; N. M. R. Peres; K. S. D. Beach; Anders W. Sandvik

2005-01-01

446

Electrical resistivity imaging of conductive plume dilution in fractured rock  

Microsoft Academic Search

Electrical resistance tomography (ERT) was used to monitor a conductive plume dilution experiment that was conducted in fractured\\u000a basalt in order to assess its applications in this type of fractured-rock environment. Tap water was injected into an injection\\u000a well for 34 days to dilute a pre-existing potassium chloride (KCl) plume at a site in Idaho, USA. No further fluids were introduced

Robin E. Nimmer; James L. Osiensky; Andrew M. Binley; Kenneth F. Sprenke; Barbara C. Williams

2007-01-01

447

The nature of the active ingredient in ultramolecular dilutions  

Microsoft Academic Search

This paper discusses the nature of the active ingredient of homeopathic ultramolecular dilutions in terms of quantitative physics.First, the problem of the nature of an active ingredient in ultramolecular dilutions is analysed leading to the recognition of the necessity of characterizing the active ingredient as a non-local quality.Second, non-locality in quantum mechanics, which is used as a paradigm, is formally

Otto Weingärtner

2007-01-01

448

Test of a Homeopathic Dilution of Aconitum napellus  

Microsoft Academic Search

SummaryBackground: Although healthy persons often report on reactions to homeopathically diluted substances, the mechanism behind such reactions remains unclear. This study examines whether a distinction can be made between the short-term reactions of healthy volunteers to a homeopathically diluted substance – Aconitum napellus C30 – and to a placebo. Participants and Methods: From the 33 subjects randomized for this double-blind,

Daryoush Piltan; Lukas Rist; Paula Simões-Wüst; Reinhard Saller

2009-01-01

449

Volume Visualization in Serial Electron Microscopy Using Local Variance David Mayerich  

E-print Network

resolution. Serial EM data sets of brain tissue can potentially be used to reconstruct the complex structure the connectome [29], the complex structure of biological neural net- works. These structures are imaged using

450

Comparison of variance and covariance patterns in parallel and serial theories of timing.  

PubMed

Parallel and serial timing processes are analyzed for their account of the dynamics of intertrial responding in the peak procedure. A strictly serial model, such as the behavioral theory of timing (Killeen & Fetterman, 1988), does not fit the dynamic correlation pattern in the location and duration of the middle high-rate responding portion of peak trials. In contrast, the parallel scalar expectancy theory model, with a sample for memory and threshold, does fit this pattern. A modification of the serial model is presented that also accommodates the within-trial covariance pattern. The modification, which is formally equivalent to a model for human tapping (Wing & Kristofferson, 1973), entails the addition of concurrent processes operating in parallel with serial timing. PMID:1602270

Gibbon, J; Church, R M

1992-05-01

451

Evolution of double-dwell serial search acquisition with automatic threshold control  

E-print Network

An evolutionary double dwell serial search acquisition ics. with automatic threshold control for a code division multiple access (CDMA) direct sequence spread spectrum system is presented and analyzed. The acquisition approach adaptively estimates...

Jung, Sung-Hyun

1998-01-01

452

Analysis of serial CT scans to assess template and catheter movement in prostate HDR brachytherapy  

Microsoft Academic Search

PurposeAs prostate high-dose-rate (HDR) brachytherapy becomes more prevalent, varying amounts of catheter displacement have been noted. To investigate the constancy of catheter position and its impact on dose distribution, we analyzed serial dosimetric CT scans.

Eduard Mullokandov; Glen Gejerman

2004-01-01

453

A forecast-driven tactical planning model for a serial manufacturing system  

E-print Network

We examine tactical planning for a serial manufacturing system that produces a product family with many process steps and low volumes. The system is subject to uncertainty in demand, in the supply of raw materials, and in ...

Chhaochhria, Pallav

454

An electrical-level superposed-edge approach to statistical serial link simulation  

E-print Network

rute-force simulation approaches to estimating serial-link bit-error rates (BERs) become computationally intractable for the case when BERs are low and the interconnect electrical response is slow enough to generate ...

Tsuk, Michael

455

The Paranormal: A Selected Bibliography of Serials and Reference Works, with Commentary.  

ERIC Educational Resources Information Center

Provides bibliography of references and serials to assist acquisitions librarians in selection of the paranormal. Topics include alchemy, astrology, magic, conjuring, witchcraft, paganism, demonology, satanism, voodooism, sorcery, cults, shamanism, UFOs, exobiology, curious physical and biological phenomena, ghosts, poltergeists, haunted places,…

Smith, Charles H.

1997-01-01

456

Paths to destruction: the lives and crimes of two serial killers.  

PubMed

Although research into the phenomenon of serial murder has revealed that serial killers frequently do not fit the initially described paradigm in terms of their physical and psychological profiles, backgrounds, and motives to kill, the media continues to sensationalize the figures of such killers and the investigators who attempt to analyze them on the basis of aspects of their crimes. Although the so-called "typical" profile of the serial murderer has proven accurate in some instances, in many other cases the demographics and behaviors of these killers have deviated widely from the generalized assumptions. This report details two unusual cases in which five and eight murders were committed in upstate New York. The lives and crimes of these offenders illustrate the wide spectrum of variations in the backgrounds, demographics, motivations, and actions witnessed among serial murderers, and highlight the limitations and dangers of profiling based on generalities. PMID:17209938

Wolf, Barbara C; Lavezzi, Wendy A

2007-01-01

457

Neural correlates of skill acquisition: Decreased cortical activity during a serial interception sequence learning task  

E-print Network

Neural correlates of skill acquisition: Decreased cortical activity during a serial interception MRI (CAMRI) and MR Neuroimaging Research, Northwestern University, 710 N Fairbanks Ct, LC 0 was observed during the practiced sequence in a distributed bilateral network including extrastriate occipital

Reber, Paul J.

458

Neural correlates of skill acquisition: Decreased cortical activity during a serial interception sequence learning task  

E-print Network

Neural correlates of skill acquisition: Decreased cortical activity during a serial interception MRI (CAMRI) and MR Neuroimaging Research, Northwestern University, 710 N Fairbanks Ct, LC 0 activity was observed during the practiced sequence in a distributed bilateral network including

Reber, Paul J.

459

Fate of phosphorus in diluted urine with tap water.  

PubMed

P loss during the fresh urine storage process is inevitable because of the presence of Ca and Mg. Dilution is one of the most important parameters influencing urine composition and subsequent P recovery. This study aimed to investigate the fate of P in urine with different dilution ratios (Vwater/Vurine, i.e., 0/100, 25/75, 50/50 and 75/25). The results indicate that the percentage of P loss increased from 43% to 76% as the dilution ratio increased from 0/100 to 75/25 because of more Ca and Mg obtained from tap water. Meanwhile, P removal efficiency through struvite precipitation decreased from 51% to 8% because of lower supersaturation ratio as a result of dilution. Struvite crystals with high purity were still obtained even under a dilution ratio of 50/50 urine solution. Batch experiments were also performed to study the influence of temperature (15-35°C) on P recovery and crystal size. For different dilution ratios of urine solutions, no significant discrepancy for the P removal efficiencies were observed at 15 and 35°C, whereas the P removal efficiencies at 25°C showed an increasing gap with those at 15 and 35°C. The largest average crystal sizes were found at 25°C, which was opposite to the trend of P removal efficiency. PMID:25065802

Liu, Xiaoning; Wen, Guoqi; Wang, Huihui; Zhu, Xiaoqi; Hu, Zhengyi

2014-10-01

460

A Serial Analysis of Gene Expression in Sun-Damaged Human Skin  

Microsoft Academic Search

To study the phenotypic changes in human skin associated with repeated sun exposure at the transcription level, we have undertaken a comparative serial analysis of gene expression of sun-damaged preauricular skin and sun-protected postauricular skin as well as sun-protected epidermis. Serial analyses of gene expression libraries, containing multiple mRNA-derived tag recombinants, were made to poly(A+)RNA isolated from human postauricular skin

Johann Urschitz; Susanne Iobst; Zsolt Urban; Chia Granda; Kathleen A. Souza; Claudia Lupp; Kurt Schilling; Ian Scott; Katalin Csiszar; Charles D. Boyd

2002-01-01

461

Coded Modulation for the Deep-Space Optical Channel: Serially Concatenated Pulse-Position Modulation  

Microsoft Academic Search

We present an error-control coding technique for optical communications. It consists of the serial concatenation of an outer convolutional code, an interleaver, a bit-accumulator, and pulse-position modulation (PPM). We refer to the coded modulation as serially concatenated PPM, or SCPPM. The encoding is accom- plished with simple shift register operations and a table look-up to map code bits to PPM

B. Moision; J. Hamkins

2005-01-01

462

Type of feature affects transfer in operant serial feature-positive discriminations  

Microsoft Academic Search

In two experiments, the effects of feature identity in operant serial feature-positive discriminations were examined with\\u000a rats. Rats were trained with two serial feature-positive discriminations (F1 ? T1+\\/ T1? and F2 ? T2+\\/ T2?), in which different\\u000a operants were reinforced with delivery of a sucrose solution during two auditory target cues (T1 and T2). The features (F1\\u000a and F2) were

Murray J. Goddard; Peter C. Holland

1996-01-01

463

Word length and age influences on forward and backward immediate serial recall  

Microsoft Academic Search

The present research is aimed at understanding the processes involved in short-term memory and how they interact with age.\\u000a Specifically, word length effects were examined under forward serial recall, backward serial recall, and item recognition\\u000a tasks, with performance being interpreted within an item-order theoretical framework. The interaction of age, word length,\\u000a and direction of recall was examined in two experiments,

Rosemary Baker; Gerald Tehan; Hannah Tehan

464

Selective Serial Multi-Antibody Biosensing with TOPAS Microstructured Polymer Optical Fibers  

PubMed Central

We have developed a fluorescence-based fiber-optical biosensor, which can selectively detect different antibodies in serial at preselected positions inside a single piece of fiber. The fiber is a microstructured polymer optical fiber fabricated from TOPAS cyclic olefin copolymer, which allows for UV activation of localized sensor layers inside the holes of the fiber. Serial fluorescence-based selective sensing of Cy3-labelled ?-streptavidin and Cy5-labelled ?-CRP antibodies is demonstrated. PMID:23529122

Emiliyanov, Grigoriy; Høiby, Poul E.; Pedersen, Lars H.; Bang, Ole

2013-01-01

465

RS485 serial port pseudo-full-duplex communication research and application  

Microsoft Academic Search

The RS-485 serial port communication is very popular in a monitoring and controlling system. A concept of RS-485 free port pseudo-full-duplex communication is presented in this paper, that is, RS-485 can not only send timed messages continuously but also receive messages at any moment from the host computer. Since RS-485 serial port has the advantage of far distance communication and

Su Xunwen; Wang Shaoping; Zhu Dongmei; Qishen Zhu

2010-01-01

466

Compartment Syndrome After Serial Casting in Spastic Diplegic Cerebral Palsy: A Case Report  

Microsoft Academic Search

Muchow RD, Flannery WD, Miedaner JA, Noonan KJ, McCarthy JJ. Compartment syndrome after serial casting in spastic diplegic cerebral palsy: a case report.We present the case of a 24-year-old woman with spastic diplegic cerebral palsy who developed left lower extremity compartment syndrome after serial casting to treat an equinus contracture. To our knowledge, this represents the first case of compartment

Ryan D. Muchow; Walker D. Flannery; James A. Miedaner; Kenneth J. Noonan; James J. McCarthy

2010-01-01

467

Serial Exhaustive Models Can Violate the Race Model Inequality: Implications for Architecture and Capacity  

Microsoft Academic Search

Classical examples of simple architectures, ranked in terms of their relative efficiency or capacity from less to more, are standard serial (1-at-a-time) processes, followed by independent parallel (simultaneous) processes, followed by coactive (pooling of parallel channel information), and interactive parallel (e.g., mutually facilitory) processes. Violation of the race model inequality has been thought to rule out ordinary parallel and serial

James T. Townsend; Georgie Nozawa

1997-01-01

468

Serially grafted polymer optical waveguides fabricated by light-induced self-written waveguide technique.  

PubMed

Serially grafted polymer optical waveguides were fabricated by the light-induced self-written (LISW) waveguide technique for the first time to our knowledge. To realize functional waveguide cores by the LISW technique, transparent materials at the writing wavelength were selected. By inserting thin transparent partitions, a serial-graft structure consisting of passive and active waveguides without any misalignment was realized automatically. This technique is advantageous for its extremely easy process over conventional fabrication techniques. PMID:18246159

Sugihara, Okihiro; Yasuda, Shuhei; Cai, Bin; Komatsu, Kyoji; Kaino, Toshikuni

2008-02-01

469

Room-temperature macromolecular serial crystallography using synchrotron radiation  

PubMed Central

A new approach for collecting data from many hundreds of thousands of microcrystals using X-ray pulses from a free-electron laser has recently been developed. Referred to as serial crystallography, diffraction patterns are recorded at a constant rate as a suspension of protein crystals flows across the path of an X-ray beam. Events that by chance contain single-crystal diffraction patterns are retained, then indexed and merged to form a three-dimensional set of reflection intensities for structure determination. This approach relies upon several innovations: an intense X-ray beam; a fast detector system; a means to rapidly flow a suspension of crystals across the X-ray beam; and the computational infrastructure to process the large volume of data. Originally conceived for radiation-damage-free measurements with ultrafast X-ray pulses, the same methods can be employed with synchrotron radiation. As in powder diffraction, the averaging of thousands of observations per Bragg peak may improve the ratio of signal to noise of low-dose exposures. Here, it is shown that this paradigm can be implemented for room-temperature data collection using synchrotron radiation and exposure times of less than 3?ms. Using lysozyme microcrystals as a model system, over 40?000 single-crystal diffraction patterns were obtained and merged to produce a structural model that could be refined to 2.1?Å resolution. The resulting electron density is in excellent agreement with that obtained using standard X-ray data collection techniques. With further improvements the method is well suited for even shorter exposures at future and upgraded synchrotron radiation facilities that may deliver beams with 1000 times higher brightness than they currently produce. PMID:25075341

Stellato, Francesco; Oberthür, Dominik; Liang, Mengning; Bean, Richard; Gati, Cornelius; Yefanov, Oleksandr; Barty, Anton; Burkhardt, Anja; Fischer, Pontus; Galli, Lorenzo; Kirian, Richard A.; Meyer, Jan; Panneerselvam, Saravanan; Yoon, Chun Hong; Chervinskii, Fedor; Speller, Emily; White, Thomas A.; Betzel, Christian; Meents, Alke; Chapman, Henry N.

2014-01-01

470

Assessing serial irregularity and its implications for health.  

PubMed

Approximate entropy (ApEn) is a recently formulated family of parameters and statistics quantifying regularity (orderliness) in serial data, with developments within theoretical mathematics as well as numerous applications to multiple biological contexts. We discuss the motivation for ApEn development, from the study of inappropriate application of dynamical systems (complexity) algorithms to general time-series settings. ApEn is scale invariant and model independent, evaluates both dominant and subordinant patterns in data, and discriminates series for which clear feature recognition is difficult. ApEn is applicable to systems with at least 50 data points and to broad classes of models: it can be applied to discriminate both general classes of correlated stochastic processes, as well as noisy deterministic systems. Moreover, ApEn is complementary to spectral and autocorrelation analyses, providing effective discriminatory capability in instances in which the aforementioned measures exhibit minimal distinctions. Representative ApEn applications to human aging studies, based on both heart rate and endocrinologic (hormonal secretory) time series, are featured. Heart rate (HR) studies include gender- and age-related changes in HR dynamics in older subjects, and analyses of "near-SIDS" infants. Endocrinologic applications establish clear quantitative changes in joint LH-testosterone secretory dynamics in older versus younger men (a "partial male menopause"), via cross-ApEn, a related two-variable asynchrony formulation; a disruption in LH-FSH-NPT (penile tumescence) synchrony in older subjects; and changes in LH-FSH secretory dynamics across menopause. The capability of ApEn to assess relatively subtle disruptions, typically found earlier in the history of a subject than mean and variance changes, holds the potential for enhanced preventative and earlier interventionist strategies. PMID:11797860

Pincus, S M

2001-12-01

471

Binswanger's encephalopathy: serial sections and morphometry of the cerebral arteries.  

PubMed

To identify arterial changes that are characteristic of Binswanger's encephalopathy (BE), we analyzed cerebral subarachnoid and medullary arteries of seven BE autopsy specimens by reconstruction of stained serial sections. We also noted the frequency of intimal fibrosis with or without atheroma of the subarachnoid arteries, and determined the medial thickness of the subarachnoid and medullary arteries. The results for the BE specimens were compared with those of six hypertensive brain hemorrhage (HH) specimens and six normotensive (NT) specimens from patients without cerebral abnormalities. In medullary arteries of BE in comparison with HH, we observed nonspecific but significantly more widespread intimal fibrosis with or without atheroma, as well as segmental loss of the medial smooth muscle cells (SMCs), which was sometimes associated with intimal plasma exudation or microaneurysm. A few medullary arteries in BE were completely occluded by fibrous connective tissue. Intimal fibrosis of the subarachnoid arteries was significantly more widespread in BE than in HH and NT. The media of the subarachnoid and medullary arteries was significantly thicker in BE and HH than in NT, and tended to be thicker in BE than in HH. In NT specimens the medullary arteries tended to be thinner in medial thickness than the subarachnoid arteries. These findings suggest that dysfunction of blood flow regulation due to increased arterial stiffness caused by hypertension-induced intimal fibrosis and loss of medial SMCs is an essential mechanism resulting in diffuse myelin loss of the cerebral white matter in BE, whereas luminal stenosis or occlusion and adventitial fibrosis are secondary. Moreover, selective and severe involvement of the cerebral medullary arteries compared with the subarachnoid arteries may be explained by the following two factors, (1) that many medullary arteries have normally dilated segments, and (2) that their media is thinner compared with that of the subarachnoid arteries of the corresponding diameter. PMID:10985691

Tanoi, Y; Okeda, R; Budka, H

2000-10-01

472

Automated Stitching of Microtubule Centerlines across Serial Electron Tomograms  

PubMed Central

Tracing microtubule centerlines in serial section electron tomography requires microtubules to be stitched across sections, that is lines from different sections need to be aligned, endpoints need to be matched at section boundaries to establish a correspondence between neighboring sections, and corresponding lines need to be connected across multiple sections. We present computational methods for these tasks: 1) An initial alignment is computed using a distance compatibility graph. 2) A fine alignment is then computed with a probabilistic variant of the iterative closest points algorithm, which we extended to handle the orientation of lines by introducing a periodic random variable to the probabilistic formulation. 3) Endpoint correspondence is established by formulating a matching problem in terms of a Markov random field and computing the best matching with belief propagation. Belief propagation is not generally guaranteed to converge to a minimum. We show how convergence can be achieved, nonetheless, with minimal manual input. In addition to stitching microtubule centerlines, the correspondence is also applied to transform and merge the electron tomograms. We applied the proposed methods to samples from the mitotic spindle in C. elegans, the meiotic spindle in X. laevis, and sub-pellicular microtubule arrays in T. brucei. The methods were able to stitch microtubules across section boundaries in good agreement with experts' opinions for the spindle samples. Results, however, were not satisfactory for the microtubule arrays. For certain experiments, such as an analysis of the spindle, the proposed methods can replace manual expert tracing and thus enable the analysis of microtubules over long distances with reasonable manual effort. PMID:25438148

Weber, Britta; Tranfield, Erin M.; Höög, Johanna L.; Baum, Daniel; Antony, Claude; Hyman, Tony; Verbavatz, Jean-Marc; Prohaska, Steffen

2014-01-01

473

Characteristics of serial electrocardiograms in heart transplant recipients.  

PubMed

To characterize "normal electrocardiogram patterns" after transplantation, serial surface 12-lead electrocardiograms (ECGs) taken 2 weeks, 1 month, and 1 year postoperatively in a group of 50 heart transplant recipients were analyzed and were correlated with clinical parameters. Some recipient atrial activity was evident in 40% of patients at 2 weeks, but in only 16% at 1 year; donor atrial activity was normal in 90% to 94% of patients at all times. ECG intervals generally were normal and did not change over time. The most prevalent abnormality was the presence of incomplete (IRBBB) or complete right bundle branch block (RBBB) patterns (14% at 2 weeks, 16% at 1 month, and 22% at 1 year). In patients with hemodynamic measurements available approximately at the time of the ECG recording 1 year following transplantation, there was a significant correlation between the presence of IRBBB and RBBB patterns and somewhat higher levels of right atrial mean pressure (6.8 versus 3.9 mm Hg, p = 0.01), pulmonary artery systolic pressure (32.5 versus 24.5 mm Hg, p = 0.001) and diastolic pressure (16.2 versus 11.2 mm Hg, p = 0.004), and right ventricular systolic pressure (31.4 versus 26.9 mm Hg, p = 0.019) and pulmonary artery wedge mean pressure (11.3 versus 7.9 mm Hg, p = 0.010). Repolarization changes were also common but decreased in frequency over time (78% at 2 weeks to 34% at 1 year) and did not correlate with the presence or absence of rejection. We conclude that ECG abnormalities in heart transplant recipients are generally mild and that IRBBB and RBBB patterns correlate with increased right heart pressures. PMID:1877454

Gao, S Z; Hunt, S A; Wiederhold, V; Schroeder, J S

1991-09-01

474

Serial measurement of portal hemodynamics after partial portal decompression.  

PubMed

In a serial analysis of splanchnic hemodynamics, we compared partial with total portal decompression in 16 alcoholic cirrhotic patients who underwent portacaval shunts for variceal hemorrhage. Partial decompression was achieved with 8 or 10 mm polytetrafluorethylene portacaval H grafts and aggressive collateral ligation. Total decompression was achieved with larger diameter H grafts (12 or 14 mm). Early and follow-up (mean interval, 18 months) postoperative studies of portal hemodynamics included: direct measurement of shunt gradients, scintigraphic quantitation of portal and mesenteric flow distribution to the liver, and a portal and splenic collateral scoring system developed from standardized splenic venography. Partial portal decompression reduced portal pressure by 43% +/- 8% compared with 81% +/- 5% after total decompression (p less than 0.01). Scintigraphy demonstrated that partial decompression provided a greater fraction of portal flow to the liver than did total decompression (57% +/- 9% versus 2% +/- 1% intrahepatic radioactivity) and mesenteric flow distribution (14.5% +/- 5.4% versus 1.2% +/- 0.7%). Only one patient with partial decompression had a significant loss of portal perfusion during the interval studies. Significantly more residual collaterals were visualized in patients with partial decompression than in those with total decompression, and interval studies showed no significant changes from early studies. We conclude that partial decompression maintains higher portal pressures, more residual collaterals, and a greater fraction of portal and mesenteric flow to the liver than does total decompression. A modest but uniform reduction of portal pressure minimizes stimulus for new collateral formation and further shunting of portal flow. PMID:3726761

Sarfeh, I J; Rypins, E B; Raiszadeh, M; Milne, N; Conroy, R M; Lyons, K P

1986-07-01

475

Motor Lateralization is characterized by a serial hybrid control scheme  

PubMed Central

Our previous studies of limb coordination in healthy right and left-handers led to the development of a theoretical model of motor lateralization, dynamic dominance, which was recently supported by studies in patients with unilateral stroke (For Review, see Sainburg, 2010: Lateralization of Goal-Directed Movements, in Human Kinetics). One of our most robust findings was on single joint movements in young healthy subjects (Sainburg and Schaefer, 2004: Interlimb differences in control of movement extent). In this study, subjects made elbow joint reaching movements toward 4 targets of different amplitudes with each arm. Whereas, both arms achieved equivalent task performance, each did so through different strategies. The dominant arm strategy scaled peak acceleration with peak velocity and movement extent, while the nondominant strategy adjusted acceleration duration to achieve the different velocities and distances. We now propose that these observed interlimb differences can be explained using a serial hybrid controller, in which movements are initiated using predictive control and terminated using impedance control. Further, we propose that the two arms should differ in the relative time that control switches from the predictive to the impedance mechanisms. We present a mathematical formulation of our hybrid controller and then test the plausibility of this control paradigm by investigating how well our model can explain interlimb differences in experimental data. Our findings confirm that the model predicts early shifts between controllers for left arm movements, which rely on impedance control mechanisms, and late shifts for right arm movements, which rely on predictive control mechanisms. This is the first computational model of motor lateralization, and is consistent with our theoretical model that emerged from empirical findings. It represents a first step in consolidating our theoretical understanding of motor lateralization into an operational model of control. PMID:21889579

Yadav, V.; Sainburg, R.L.

2011-01-01

476

Finding the answer in space: the mental whiteboard hypothesis on serial order in working memory  

PubMed Central

Various prominent models on serial order coding in working memory (WM) build on the notion that serial order is achieved by binding the various items to-be-maintained to fixed position markers. Despite being relatively successful in accounting for empirical observations and some recent neuro-imaging support, these models were largely formulated on theoretical grounds and few specifications have been provided with respect to the cognitive and/or neural nature of these position markers. Here we outline a hypothesis on a novel candidate mechanism to substantiate the notion of serial position markers. Specifically, we propose that serial order WM is grounded in the spatial attention system: (I) The position markers that provide multi-item WM with a serial context should be understood as coordinates within an internal, spatially defined system; (II) internal spatial attention is involved in searching through the resulting serial order representation; and (III) retrieval corresponds to selection by spatial attention. We sketch the available empirical support and discuss how the hypothesis may provide a parsimonious framework from which to understand a broad range of observations across behavioral, neural and neuropsychological domains. Finally, we pinpoint what we believe are major questions for future research inspired by the hypothesis. PMID:25505394

Abrahamse, Elger; van Dijck, Jean-Philippe; Majerus, Steve; Fias, Wim

2014-01-01

477

Differential effects of paced and unpaced responding on delayed serial order recall in schizophrenia.  

PubMed

Working memory for temporal order is a component of working memory that is especially dependent on striatal systems, but has not been extensively studied in schizophrenia. This study was designed to characterize serial order reproduction by adapting a spatial serial order task developed for nonhuman primate studies, while controlling for working memory load and whether responses were initiated freely (unpaced) or in an externally paced format. Clinically stable schizophrenia patients (n=27) and psychiatrically healthy individuals (n=25) were comparable on demographic variables and performance on standardized tests of immediate serial order recall (Digit Span, Spatial Span). No group differences were observed for serial order recall when read sequence reproduction was unpaced. However, schizophrenia patients exhibited significant impairments when responding was paced, regardless of sequence length or retention delay. Intact performance by schizophrenia patients during the unpaced condition indicates that prefrontal storage and striatal output systems are sufficiently intact to learn novel response sequences and hold them in working memory to perform serial order tasks. However, retention for newly learned response sequences was disrupted in schizophrenia patients by paced responding, when read-out of each element in the response sequence was externally controlled. The disruption of memory for serial order in paced read-out condition indicates a deficit in frontostriatal interaction characterized by an inability to update working memory stores and deconstruct 'chunked' information. PMID:21705197

Hill, S Kristian; Griffin, Ginny B; Houk, James C; Sweeney, John A

2011-09-01

478

Effects of dietary dilution source and dilution level on feather damage, performance, behavior, and litter condition in pullets.  

PubMed

An experiment was conducted to investigate the effects of dietary dilution sources and levels on feather damage, performance, feeding behavior, and litter condition in rearing pullets. It was hypothesized that dietary dilution increases feeding-related behavior and improves feather condition, particularly if insoluble nonstarch polysaccharides are used as the dilution source. In total, 864 Lohmann Brown 1-d-old non-beak-trimmed pullets were used until 18 wk of age. Four dietary treatments, a control diet without any dilution (R_0%), 7.5% diluted diet with sunflower seed extract/oat hulls (R_7.5%), 15% diluted diet with sunflower seed extract (R_15%_S), and 15% diluted diet with oat hulls (R_15%_O), with 6 replicates (1 replicate is a pen with 36 pullets) per treatment were used. On 4-wk intervals, behavioral parameters, including eating time, feather pecking, feather condition, and general behavior were evaluated. Pullets fed the control diet showed increased feather, comb, and wire pecking compared with pullets fed diluted diets. The level of feather damage decreased with increasing dietary dilution level. Pullets receiving R_15%_S and R_15%_O showed more feeding-related behavior than the pullets on R_7.5% and R_0%. Oat hulls were more effective in preventing feather damage than sunflower seed extract. Pullets did not fully compensate their feed intake if fed a dietary dilution, resulting in a proportionally reduced available ME intake. The R_15%_O pullets had 2.9% lower average BW gain compared with those fed R_0%. Average eating duration increased by 12.8, 33.2, and 42.1% in R_7.5%, R_15%_S, and R_15%_O fed pullets, respectively, compared with R_0%, whereas eating rate [feed intake (g)/pullet per eating min] was decreased in R_15%_S and R_15%_O pullets. Relative weights of empty gizzards were 3.95, 10.30, and 62.72% greater in R_7.5%, R_15%_S, and R_15%_O pullets compared with pullets fed R_0%. It was concluded that dietary dilution affected time budgets of the pullets, as shown by more feeding-related behavior, resulting in less feather pecking behavior. Based on our results, application of this feeding strategy could improve production and welfare in pullets. PMID:23436509

Qaisrani, S N; van Krimpen, M M; Kwakkel, R P

2013-03-01

479

Influence of ZnO on the properties of dilute and semi-dilute cellulose-NaOH-water solutions  

E-print Network

Influence of ZnO on the properties of dilute and semi-dilute cellulose-NaOH-water solutions Weiqing (EPNOE), www.epnoe.eu hal-00595331,version1-11Dec2012 Author manuscript, published in "Cellulose 18, 4 (2011) Pages 911-920" DOI : 10.1007/s10570-011-9552-9 #12;1 Abstract The influence of ZnO as cellulose-8

Paris-Sud XI, Université de

480

Dilution Ratios for HB Line Phase I Eductor System  

SciTech Connect

HB Line Phase I product transfer includes an eductor which transfers liquid from Product Hold Tank (PHT) RT-33 or RT-34 to Tank 11.1. The eductor also dilutes the liquid from the PHT with eductant. Dilution must be reliably controlled because of criticality concerns with H Canyon Tanks. The eductor system, which contains a 1 inch Model 264 Schutte and Koerting eductor, was previously modeled [1] in 1998 and dilution ratios were calculated for different flow restrictors, eductant pressures and densities for the eductant and the contents of the PHT. The previous calculation was performed using spreadsheet software no longer supported at SRS. For the previous work dilution ratio was defined as the volume of eductant consumed divided by volume of PHT contents transferred. Since 1998 HB Line Engineering has changed the definition of dilution ratio to the total volume of liquid, eductant consumed plus the volume of PHT liquid transferred, divided by the volume of PHT liquid transferred. The 1998 base case calculation was for a restrictor diameter of 0.334 inches, an eductant supply pressure of 15 psig, full PHT, an eductant specific gravity of 1.385 and a PHT density of 1.015. The base case dilution ratio calculated in 1998 using the current definition was 3.52. After accounting for uncertainty the minimum dilution ratio decreased to 3.23. In 2001 HB Line Engineering requested that the calculation be repeated for a manganous nitrate solution eductant and also a process water eductant. The other conditions were the same as for the 1998 calculation. The objective of this report is to document the calculations and the results.

Steimke, J.L.

2002-01-31

481

Permanent physico-chemical properties of extremely diluted aqueous solutions of homeopathic medicines  

Microsoft Academic Search

The purpose of this study was to obtain information about the influence of successive dilutions and succussions on the water structure. ‘Extremely diluted solutions’ (EDS) are solutions obtained through the iteration of two processes: dilution in stages of 1:100 and succussion, typically used in homeopathic medicine. The iteration is repeated until extreme dilutions are reached, so that the chemical composition

V. Elia; S. Baiano; I. Duro; E. Napoli; M. Niccoli; L. Nonatelli

2004-01-01

482

Effect of different attentional instructions on the acquisition of a serial movement task.  

PubMed

Recent research in attentional focus of instruction has predominantly over-emphasized the investigation of discrete and continuous skills rather than serial skills. The purpose of this study was therefore to examine the effect of different attentional focus instructions on learning a serial skill task (i.e., taekwondo routine) in novice learners. It was predicted that the use of movement outcome instructions could enhance the learning of a serial skill as previously supported in studies examining the acquisition of discrete and continuous skills. Thirteen female participants were recruited for this study and were assigned to either movement form condition - control group (n = 7) or movement outcome condition - treatment group (n = 6). All participants underwent 12 practice sessions over an 8-week period with their respective instructional conditions with each session lasting 30 minutes. Video recording of the serial skill tasks (hand techniques, kicking techniques and 10-step routine) were captured at "the-twelfth-training session", "after 1-week", and "after 1-month". It was found that more participants in the treatment group obtained a higher score in all three serial skill tasks, especially in Mastery component of 'Kicking' techniques at 'after 1-week' (p < 0.05, r = 0.57). This study suggested that movement outcome instructions have positive medium effect on balance control for serial skill task, especially in kicking actions. Key PointsMovement outcome (MO) instructions have a positive impact on learning a serial task, especially in kicking actions.More functional coordination during movement executions for MO participants.Benefits for MO instructions may be individual specific. PMID:25435770

Woo, Mei Teng; Chow, Jia Yi; Koh, Michael

2014-12-01

483

Effect of Different Attentional Instructions on the Acquisition of a Serial Movement Task  

PubMed Central

Recent research in attentional focus of instruction has predominantly over-emphasized the investigation of discrete and continuous skills rather than serial skills. The purpose of this study was therefore to examine the effect of different attentional focus instructions on learning a serial skill task (i.e., taekwondo routine) in novice learners. It was predicted that the use of movement outcome instructions could enhance the learning of a serial skill as previously supported in studies examining the acquisition of discrete and continuous skills. Thirteen female participants were recruited for this study and were assigned to either movement form condition - control group (n = 7) or movement outcome condition – treatment group (n = 6). All participants underwent 12 practice sessions over an 8-week period with their respective instructional conditions with each session lasting 30 minutes. Video recording of the serial skill tasks (hand techniques, kicking techniques and 10-step routine) were captured at “the-twelfth-training session”, “after 1-week”, and “after 1-month”. It was found that more participants in the treatment group obtained a higher score in all three serial skill tasks, especially in Mastery component of ‘Kicking’ techniques at ‘after 1-week’ (p < 0.05, r = 0.57). This study suggested that movement outcome instructions have positive medium effect on balance control for serial skill task, especially in kicking actions. Key Points Movement outcome (MO) instructions have a positive impact on learning a serial task, especially in kicking actions. More functional coordination during movement executions for MO participants. Benefits for MO instructions may be individual specific. PMID:25435770

Woo, Mei Teng; Chow, Jia Yi; Koh, Michael

2014-01-01

484

High-dilution effects revisited. 2. Pharmacodynamic mechanisms.  

PubMed

The pharmacodynamics aspects of homeopathic remedies are appraised by laboratory studies on the biological effects at various levels (cellular, molecular and systemic). The major question is how these medicines may work in the body. The possible answers concern the identification of biological targets, the means of drug-receptor interactions, the mechanisms of signal transmission and amplification, and the models of inversion of effects according to the traditional 'simile' rule. These problems are handled by two experimental and theoretical lines, according to the doses or dilutions considered (low-medium versus high dilutions). Homeopathic formulations in low-medium dilutions, containing molecules in the range of ultra-low doses, exploit the extreme sensitivity of biological systems to exogenous and endogenous signals. Their effects are interpreted in the framework of hormesis theories and paradoxical pharmacology. The hypotheses regarding the action mechanisms of highly diluted/dynamized solutions (beyond Avogadro-Loschmidt limit) variously invoke sensitivity to bioelectromagnetic information, participation of water chains in signalling, and regulation of bifurcation points of systemic networks. High-dilution pharmacology is emerging as a pioneering subject in the domain of nanomedicine and is providing greater plausibility to the puzzling claims of homeopathy. PMID:24439453

Bellavite, Paolo; Marzotto, Marta; Olioso, Debora; Moratti, Elisabetta; Conforti, Anita

2014-01-01

485

Dilution cycle control for an absorption refrigeration system  

DOEpatents

A dilution cycle control system for an absorption refrigeration system is disclosed. The control system includes a time delay relay for sensing shutdown of the absorption refrigeration system and for generating a control signal only after expiration of a preselected time period measured from the sensed shutdown of the absorption refrigeration system, during which the absorption refrigeration system is not restarted. A dilution cycle for the absorption refrigeration system is initiated in response to generation of a control signal by the time delay relay. This control system is particularly suitable for use with an absorption refrigeration system which is frequently cycled on and off since the time delay provided by the control system prevents needless dilution of the absorption refrigeration system when the system is turned off for only a short period of time and then is turned back on.

Reimann, Robert C. (Lafayette, NY)

1984-01-01

486

Gas dilution system results and application to acid rain utilities  

SciTech Connect

In 1997, the United States EPA will remove restrictions preventing acid rain utilities from using gas dilution systems for calibration or linearity studies for continuous emissions monitoring, Test Method 205 in 40CFR51 requires that a gas dilution system must produce calibration gases whose measured values are within {+-}2% of predicted values. This paper presents the evaluation of the Environics/CalMat 2020 Dilution System for use in calibration studies. Internal studies show that concentrations generated by this unit are within {+-}0.5% of predicted values. Studies are being conducted by several acid rain utilities to evaluate the Environics/CalMat system using single minor component calibration standards. In addition, an internally generated study is being performed to demonstrate the system`s accuracy using a multi-component gas mixture. Data from these tests will be presented in the final version of the paper.

Jolley-Souders, K.; Geib, R. [Matheson Gas Products, Montgomeryville, PA (United States); Dunn, C. [Environics, Inc., Tolland, CT (United States)

1997-12-31

487

Application of cryocoolers to a vintage dilution refrigerator  

NASA Astrophysics Data System (ADS)

A dilution refrigerator is required for 50 mK detector operation of CDMS (Cryogenic Dark Matter Search). Besides shielding the dilution refrigerator itself, the liquid nitrogen shield and liquid helium bath in the refrigerator cool the detector cryostat heat shields and cool electronics, resulting in significant external heat loads at 80 K and at 4 K. An Oxford Instruments Kelvinox 400 has served this role for ten years but required daily transfers of liquid nitrogen and liquid helium. Complicating the cryogen supply is the location 800 meters below ground in an RF shielded, class 10000 clean room at Soudan, MN. Nitrogen and helium re-liquefiers using cryocoolers were installed outside the clean room and continuously condense room temperature gas and return the liquids to the dilution refrigerator through a transfer line. This paper will describe the design, installation, controls and performance of liquefaction systems.

Schmitt, Richard L.; Smith, Gary; Ruschman, Mark; Beaty, Jim

2012-06-01

488

Process of concentrating ethanol from dilute aqueous solutions thereof  

DOEpatents

Relatively dilute aqueous solutions of ethanol are concentrated by passage through a bed of a crystalline silica polymorph, such as silicalite, to adsorb the ethanol with residual dilute feed in contact with the bed, which is displaced by passing concentrated aqueous ethanol through the bed without displacing the adsorbed ethanol. A product concentrate is then obtained by removing the adsorbed ethanol from the bed together with at least a portion of the concentrated aqueous ethanol used as the displacer liquid. This process permits ethanol to be concentrated from dilute fermentation beers, which may contain from 6 to 10% ethanol, to obtain a concentrate product at very low energy cost having an ethanol concentration in excess of 95%, such as a concentration of from 98 to 99.5%. 5 figs.

Oulman, C.S.; Chriswell, C.D.

1981-07-07

489

Process of concentrating ethanol from dilute aqueous solutions thereof  

DOEpatents

Relatively dilute aqueous solutions of ethanol are concentrated by passage through a bed of a crystalline silica polymorph, such as silicalite, to adsorb the ethanol with residual dilute feed in contact with the bed, which is displaced by passing concentrated aqueous ethanol through the bed without displacing the adsorbed ethanol. A product concentrate is then obtained by removing the adsorbed ethanol from the bed together with at least a portion of the concentrated aqueous ethanol used as the displacer liquid. This process permits ethanol to be concentrated from dilute fermentation beers, which may contain from 6 to 10% ethanol, to obtain a concentrate product at very low energy cost having an ethanol concentration in excess of 95%, such as a concentration of from 98 to 99.5%.

Oulman, Charles S. [Ames, IA; Chriswell, Colin D. [Slater, IA

1981-07-07

490

Maximum First Transfer and Dilution Volumes for 241SY101  

SciTech Connect

This report discusses the solution to the following problem: what is the maximum waste transfer and dilution quantities and locations which can be allowed in the first transfer of waste from SY-101 given the following constraints? (1) The crust must float on the submerged waste (waste becomes less dense when diluted, eventually allowing crust to sink); (2) No credit is taken for the top dilution; (3) Addition of water to the bulk slurry through the transfer pump must be able to refloat the crust base to above 295 inches; (4) The margin between refloating to 295 inches and crust sinking must be at least 10,000 gallons; (5) The crust can't be thinned to less than 60 inches thick.

BARTON, W.B.

1999-10-28

491

Use of an Eductor to Reliably Dilute a Plutonium Solution  

SciTech Connect

Savannah River Site (SRS) in South Carolina is dissolving Pu239 scrap, which is a legacy from the production of nuclear weapons materials, and will later convert it into oxide form to stabilize it. An eductor has been used to both dilute and transfer a plutonium containing solution between tanks. Eductors have the advantages of simplicity and no moving parts. Reliable control of dilution is important because the geometry of the receiving tank could potentially allow a nuclear criticality. Dilution factor was to have been controlled by the appropriate choice of flow restrictor in the line between the plutonium solution tank and the eductor. However, dilution factors measured for liquid transfers with different flow restrictors showed unexpected trends, causing concern that the process was not well understood. As a result, the performance of the eductor and associated piping were analyzed using a mathematical model. The one dimensional, two phase model accounted for eductor performance and for air and vapor coming out of solution at low pressures. The unexpected trends were shown to be the result of variations in viscosities and densities of both the plutonium solution and the nitric acid solution used as both the motive fluid and diluent. The model agreed well with existing data and was then used to make pre-test predictions of flows for four solution transfers with good agreement. This provided confidence that the eductor system was a reliable method for obtaining specified dilution factors. Based on model results, recommendations were made and implemented for the operation of the eductor transfer system. One unexpected result of the analysis was the observation that slow corrosion inside the eductor is increasing the dilution factor, which is a conservative trend.

Steimke, J.L.

1999-03-23

492

System and method for simultaneously collecting serial number information from numerous identity tags  

DOEpatents

A system and method are disclosed for simultaneously collecting serial number information reports from numerous colliding coded-radio-frequency identity tags. Each tag has a unique multi-digit serial number that is stored in non-volatile RAM. A reader