Note: This page contains sample records for the topic tze huang pzh from Science.gov.
While these samples are representative of the content of Science.gov,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of Science.gov
to obtain the most current and comprehensive results.
Last update: November 12, 2013.
1

Protective effects and potential mechanisms of Pien Tze Huang on cerebral chronic ischemia and hypertensive stroke  

PubMed Central

Background Stroke caused by brain ischemia is the third leading cause of adult disability. Active prevention and early treatment of stroke targeting the causes and risk factors may decrease its incidence, mortality and subsequent disability. Pien Tze Huang (PZH), a Chinese medicine formula, was found to have anti-edema, anti-inflammatory and anti-thrombotic effects that can prevent brain damage. This study aims to investigate the potential mechanisms of the preventive effects of Pien Tze Huang on brain damage caused by chronic ischemia and hypertensive stroke in rats. Methods The effects of Pien Tze Huang on brain protein expression in spontaneously hypertensive rat (SHR) and stroke prone SHR (SHRsp) were studied with 2-D gel electrophoresis and mass spectrometric analysis with a matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF)/TOF tandem mass spectrometer and on brain cell death with enzyme link immunosorbent assay (ELISA) and immunostaining. Results Pien Tze Huang decreased cell death in hippocampus and cerebellum caused by chronic ischemia and hypertensive stroke. Immunostaining of caspase-3 results indicated that Pien Tze Huang prevents brain cells from apoptosis caused by ischemia. Brain protein expression results suggested that Pien Tze Huang downregulated QCR2 in the electron transfer chain of mitochondria preventing reactive oxygen species (ROS) damage and possibly subsequent cell death (caspase 3 assay) as caused by chronic ischemia or hypertensive stroke to hippocampus and cerebellum. Conclusion Pien Tze Huang showed preventive effects on limiting the damage or injury caused by chronic ischemia and hypertensive stroke in rats. The effect of Pien Tze Huang was possibly related to prevention of cell death from apoptosis or ROS/oxidative damage in mitochondria.

2010-01-01

2

Protective effects and potential mechanisms of Pien Tze Huang on cerebral chronic ischemia and hypertensive stroke  

Microsoft Academic Search

BACKGROUND: Stroke caused by brain ischemia is the third leading cause of adult disability. Active prevention and early treatment of stroke targeting the causes and risk factors may decrease its incidence, mortality and subsequent disability. Pien Tze Huang (PZH), a Chinese medicine formula, was found to have anti-edema, anti-inflammatory and anti-thrombotic effects that can prevent brain damage. This study aims

Lihong Zhang; Wai Ping Lam; Lanhai Lü; Chunmei Wang; Yeuk Wa Wong; Lok Hang Lam; Hong Chai Tang; Maria Sen Mun Wai; Mingwei Wang; Wing Hang Kwong; Sai Ming Ngai; Ying Tat Mak; David Tai Wai Yew

2010-01-01

3

Revised Huang-Yang multipolar pseudopotential  

SciTech Connect

A number of authors have recently pointed out inconsistencies of results obtained with the Huang-Yang multipolar pseudopotential for low-energy scattering [K. Huang and K. C. Yang, Phys. Rev. 105, 767 (1957); later revised by Huang, Statistical Mechanics (Wiley, New York, 1963)]. The conceptual validity of their original derivation has been questioned. Here I show that these inconsistencies are rather due to an algebraic mistake made by Huang and Yang. With the corrected error, I present the revised version of the multipolar pseudopotential.

Derevianko, Andrei [Department of Physics, University of Nevada, Reno, Nevada 89557 (United States)

2005-10-15

4

The summary of Hilbert-Huang transform  

NASA Astrophysics Data System (ADS)

The widely investigated signals are mainly nonstationary and nonlinear signals, thus it is difficult to get the precise information from the nonstationary and nonlinear signals. Here we introduce a new method to process the nonstationary and nonlinear signals. And this new algorithm makes a good performance on processing the nonstationary and nonlinear signals. This paper mainly describe the basic theory of the new algorithm——Hilbert-Huang Transform. The Hilbert-Huang Transform is composed of Empirical Mode Decomposition and Hilbert transform. The problems of this arithmetic are summarized, such as the end effects, stop criterion and so on, and the solutions of these problems are put forward. This paper also provides some improved methods based on the Empirical Mode Decomposition in the end, such as Adaptive Time Varying Filter Decomposition, Extremum filed Mean Mode Decomposition and Improved Extremum field Mean Mode Decomposition.

Song, Shi-De; Yao, Zhi-chao; Wang, Xiao-Na

2013-09-01

5

[Ma Huang, from dietary supplement to abuse].  

PubMed

Dietary supplements containing Ma Huang (chinease ephedra) are available on the web sites and dietary shops in USA. They are widely promoted and used as a mean of weight reduction and energy enhancement. They contain Ma Huang alone or combined with Guarana (caffeine), creatine, St John's wort, carnitine and are proposed with different labels. Numerous reports of adverse reactions and acute intoxication related to these products use were described in the medical literature. In the light of the severity of these cases, some of which resulted in permanent injury and death, the Food and Drug Administration has proposed limits on the dose and duration of use of such supplements. A review of 140 reports submitted to the FDA between June 1997 and March 1999, 47% involved cardiovascular symptoms, 18% neurological symptoms. Severe hypertension was the single most frequent adverse effect followed by tachycardia, myocardial infarction, stroke, seizure. Ten events resulted in death and 13 produced permanent impairment. In France, ampleness of the use of dietary supplements containing ephedra alkaloids is unknown. Two French recent severe poisonings (one with "ripped Fuel" for losing weight and the other with "Energy pills" in a body builder) show that there is serious health risks for the chronic users. Dietary supplements are not subject to control under "la Direction Générale de la Santé". Informations for general public, medical community and health-care authorities are necessary to be aware of potential health hazards of these products use. PMID:11974441

Arditti, J; Bourdon, J H; Spadari, M; de Haro, L; Richard, N; Valli, M

2002-01-01

6

Huang Zunxian and His Association with Meiji Era Japanese Literati (\\  

Microsoft Academic Search

The great Chinese poet Huang Zunxian, who served from 1877 to 1882 as a high-ranking member of the staff of the Qing legation in Tokyo, became closely acquainted with and spent much time in the company of prominent Japanese literati (bunjin). Huang's experiences with these men provide an extremely valuable window of information and insight into the intellectual atmosphere of

Richard John Lynn

2003-01-01

7

Analysis of Sunspot Variability Using the Hilbert - Huang Transform  

NASA Astrophysics Data System (ADS)

The Hilbert - Huang transform is a relatively new data analysis technique, which is able to analyze the cyclic components of a potentially nonlinear and nonstationary data series. Monthly sunspot number data from 1749 to 2010 were analyzed using this technique, which revealed the different variability inherent in the data including the 11-year (Schwabe), 20 - 50-year (quasi-Hale) and 60 - 120-year (Gleissberg) cycles. The results were compared with traditional Fourier analysis. The Hilbert - Huang transform is able to provide a local and adaptive description of the intrinsic cyclic components of sunspot number data, which are nonstationary and which are the result of nonlinear processes.

Barnhart, Bradley L.; Eichinger, William E.

2011-04-01

8

Detection for steganography based on Hilbert Huang Transform  

NASA Astrophysics Data System (ADS)

This paper will introduce the Hilbert-Huang Transform for Analysis of Universal blind steganalysis detection task. Firstly, This method use its efficient unsteady-state modeling ability to constucte features of steganography object and adopt independent variable analysis method to extract and refine feature. In the classification stage, by constructing the compound ANOVN kernel function of the Steganalysis field to improve data processing capabilities of nonlinear.

Wu, Suyan; Li, Wenbo; Shi, Yanqin

2011-10-01

9

Aqueous extract of ma huang suppresses neuropeptide Y expression in food-deprived rat hypothalamus.  

PubMed

Ma huang, the dried plant stem of ephedra intermedia Schrenk et C.A., contains an ephedrine-type alkaloid and has been used for weight loss. Neuropeptide Y (NPY), a 36-amino acid peptide, is concentrated in the hypothalamus and stimulates feeding desire. In this study, the effect of ma huang on the expressions of NPY in the hypothalamus of rats was investigated using immunohistochemistry. Food-deprivation enhanced the NPY expression in the hypothalamus. ma huang suppressed the food-deprivation-induced enhancement of NPY expression. Present results suggest that ma huang curbs the food desire by suppressing the NPY expression under food-deprivation conditions. PMID:15633802

Kim, Ee-Hwa; Shin, Mal-Soon; Chang, Hyun-Kyung; Lee, Taeck-Hyun; Jang, Mi-Hyeon; Shin, Min-Chul; Lee, Sam-Jun; Kim, Chang Ju

2004-01-01

10

Time series analysis with the Hilbert-Huang transform  

NASA Astrophysics Data System (ADS)

Time series data can be transformed to the frequency domain via the Hilbert-Huang transform. This transform has two major stages. The data are first deconstructed into a set of monocomponent intrinsic mode functions that are the basis states for the transform. A Hilbert spectral analysis is then performed on each of these basis states, yielding time dependent amplitude and frequency information. The process of extracting the intrinsic mode functions and performing Hilbert spectral analysis is described and applied to a set of examples that show the advantages and shortcomings of this transform.

Donnelly, Denis; Rogers, Edwin

2009-12-01

11

Application of Hilbert-Huang transform to laser Doppler velocimeter  

NASA Astrophysics Data System (ADS)

A new method based on Hilbert-Huang transform is proposed to analyze the laser Doppler signal with a large acceleration. The Doppler signal is decomposed into several Intrinsic Mode Functions (IMFs) via empirical mode decomposition (EMD). And the Hilbert transform is used to compute the instantaneous frequency. The vehicle velocity parameter is estimated by taking linear fitting on the instantaneous frequency of the relevant IMF. The simulation results show that the HHT-based method is quite useful for the LDV that offers velocity parameter to the vehicle self-contained navigation system when the vehicle moves at a large acceleration.

Xiaoming, Nie; Jian, Zhou; Xingwu, Long

2012-10-01

12

Magnetotelluric Response Function Estimation Based on Hilbert-Huang Transform  

NASA Astrophysics Data System (ADS)

Magnetotelluric (MT) data series are non-stationary random signals that do not meet the basic requirements of conventional methods based on the Fourier transform. To minimize the estimation bias errors brought about by the non-stationary characteristics of MT data, a new method, based on the Hilbert-Huang transform (HHT), is proposed for the first time for estimating the MT response functions from a time series of electromagnetic field variations. With the HHT method, the amplitude of data series are expressed as a function of frequency and time and then response functions are estimated statistically from the time-frequency spectrum. Mathematical model and calculation processes are introduced and some simulated data are analyzed to verify the correctness of the method. Finally, the measured MT data is facilitated by applying the HHT to assess the ability of HHT method to quantify meaningful geologic information.

Cai, Jian-hua

2012-11-01

13

The Hilbert-Huang transform: Theory, applications, development  

NASA Astrophysics Data System (ADS)

Hilbert-Huang Transform (HHT) is a data analysis tool, first developed in 1998, which can be used to extract the periodic components embedded within oscillatory data. This thesis is dedicated to the understanding, application, and development of this tool. First, the background theory of HHT will be described and compared with other spectral analysis tools. Then, a number of applications will be presented, which demonstrate the capability for HHT to dissect and analyze the periodic components of different oscillatory data. Finally, a new algorithm is presented which expands HHT ability to analyze discontinuous data. The sum result is the creation of a number of useful tools developed from the application of HHT, as well as an improvement of the HHT tool itself.

Barnhart, Bradley Lee

14

Alpha and Theta Wave Localisation using Hilbert-Huang Transform: Empirical Study of the Accuracy  

Microsoft Academic Search

This paper proposes to apply the Hilbert-Huang Transform (HHT) to locate alpha and theta waves in an Electroence phalogram (EEG), in order to estimate the vigilance level of an operator. The Hilbert-Huang Transform (HHT) is a recent technique for non-stationary signal processing. Using the Empirical Mode Decomposition (EMD), the HHT allows decomposing a multi-modal signal into a sum of mono-contribution

Hassan SHARABATY; Jordi MARTIN; B. Jammes; D. Esteve

2006-01-01

15

Huang-Rhys Factor of CdTe Semiconductors Doped with Arsenic and Antimony  

Microsoft Academic Search

By using the evolution operator method, we report a careful derivation of the Huang-Rhys factor, based on the Fröhlich continuum model of polarons, for cadmium telluride (CdTe) semiconductors, doped with arsenic (As) and antimony (Sb) acceptors. The calculated values of the Huang-Rhys factor, agree well with the experimental data for the bands at 1.45 eV and 1.54 eV, at large

S. Baskoutas; N. S. Athanasiou

1997-01-01

16

Application of Hilbert-Huang signal processing to ultrasonic non-destructive testing of oil pipelines  

Microsoft Academic Search

In this paper, a detection technique for locating and determining the extent of defects and cracks in oil pipelines based\\u000a on Hilbert-Huang time-frequency analysis is proposed. The ultrasonic signals reflected from defect-free pipelines and from\\u000a pipelines with defects were processed using Hilbert-Huang transform, a recently developed signal processing technique based\\u000a on direct extraction of the energy associated with the intrinsic

Yi-mei Mao; Pei-wen Que

2006-01-01

17

Tan's distributions and Fermi-Huang pseudopotential in momentum space  

NASA Astrophysics Data System (ADS)

The long-standing question of finding the momentum representation for the s-wave zero-range interaction in three spatial dimensions is here solved. This is done by expressing a certain distribution, introduced in a formal way in [S. Tan, Ann. Phys. (NY)APNYA60003-491610.1016/j.aop.2008.03.004 323, 2952 (2008)], explicitly. The resulting form of the Fourier-transformed pseudopotential remains very simple. Operator forms for the so-called Tan's selectors, which, together with Fermi-Huang pseudopotential, largely simplify the derivation of Tan's universal relations for the Fermi gas, are here derived and are also very simple. A momentum cutoff version of the pseudopotential is also provided, and with this no apparent contradiction to the notion of integrals in Tan's methods is left. The equivalence, even at the intermediate-step level, between the pseudopotential approach and momentum-space renormalization of the bare Dirac delta interaction is then shown by using the explicit form of the cutoff pseudopotential.

Valiente, Manuel

2012-01-01

18

Fault pattern and oil migration in Huang Hua depression, China  

SciTech Connect

Huang Hua depression is a back-arc intercratonic rift basin that developed on the north China platform in the Cenozoic. Controlled by the basement anisotropy, multidirectional fault sets on the plane are developed along the preexisting zone of weakness. According to the scale of tectonic elements controlled by faults, as well as its time of activity and depth, normal faults are divided into four grades in this basin. Seismic data and geological information have shown that 70% of the faults are listric faults. Flattening of the faults reflect tilting of fault block or detachment along the unconformity surfaces and ductile beds. Because of gravity creep and local extension main faults and secondary faults are united into a [open quotes]horse tail[close quotes] or [open quotes]Y[close quotes] patterns. Results of oil-source rock correlation and oil migration parameters all demonstrate that oil and gas migrate in or through faults (fracture zones), and form the [open quotes]step-like[close quotes] migration model. Faults in sandstone-shale sequences play the role of conduits for hydrocarbon, but faults in gypsum beds and thick undercompacted shales generally act as a top seal. To prevent oil migration through faults, reservoirs and ductile rocks with a high capillary displacement pressure must be juxtaposed. Whether faults are rejuvenated during hydrocarbon migration is not required for faults opening, but it is important to investigate the activity history of growth faults and the role of juxtaposed sediments in a sandstone-shale sequence in creating sealing and nonsealing faults.

Zhou, Guojun (West Virginia Univ., Morgantown, WV (United States))

1994-08-01

19

Seizure classification in EEG signals utilizing Hilbert-Huang transform  

PubMed Central

Background Classification method capable of recognizing abnormal activities of the brain functionality are either brain imaging or brain signal analysis. The abnormal activity of interest in this study is characterized by a disturbance caused by changes in neuronal electrochemical activity that results in abnormal synchronous discharges. The method aims at helping physicians discriminate between healthy and seizure electroencephalographic (EEG) signals. Method Discrimination in this work is achieved by analyzing EEG signals obtained from freely accessible databases. MATLAB has been used to implement and test the proposed classification algorithm. The analysis in question presents a classification of normal and ictal activities using a feature relied on Hilbert-Huang Transform. Through this method, information related to the intrinsic functions contained in the EEG signal has been extracted to track the local amplitude and the frequency of the signal. Based on this local information, weighted frequencies are calculated and a comparison between ictal and seizure-free determinant intrinsic functions is then performed. Methods of comparison used are the t-test and the Euclidean clustering. Results The t-test results in a P-value < 0.02 and the clustering leads to accurate (94%) and specific (96%) results. The proposed method is also contrasted against the Multivariate Empirical Mode Decomposition that reaches 80% accuracy. Comparison results strengthen the contribution of this paper not only from the accuracy point of view but also with respect to its fast response and ease to use. Conclusion An original tool for EEG signal processing giving physicians the possibility to diagnose brain functionality abnormalities is presented in this paper. The proposed system bears the potential of providing several credible benefits such as fast diagnosis, high accuracy, good sensitivity and specificity, time saving and user friendly. Furthermore, the classification of mode mixing can be achieved using the extracted instantaneous information of every IMF, but it would be most likely a hard task if only the average value is used. Extra benefits of this proposed system include low cost, and ease of interface. All of that indicate the usefulness of the tool and its use as an efficient diagnostic tool.

2011-01-01

20

Hilbert-Huang Transform (HHT) for low frequency waves determination: THEMIS data analysis  

NASA Astrophysics Data System (ADS)

The application of Hilbert-Huang Transform (HHT) is considered for the determination of the instantaneous wave vector of the low frequency plasma waves in the turbulent magnetosheath. Downstream of a quasi-perpendicular bow shock of the Earth, various wave modes associated with the different boundaries have been confirmed and different methods have been used to find frequency and instantaneous frequency of the different modes. We applied Hilbert-Huang Transform in the determination of instantaneous frequency by decomposing the data observed by in-situ spacecraft in magnetosheath into intrinsic mode functions (IMFs) using empirical mode decomposition (EMD) technique of Huang et al., 1998. Instantaneous frequencies for the different IMFs were computed using Hilbert transform. The determined instantaneous frequency supports the non-stationary and non-linear nature of the data. Near-bow shock region data from the THEMIS mission were used.

Beloff, Natalia; Nathaniel, Ekong

21

Methods for detection and characterization of signals in noisy data with the Hilbert-Huang transform  

NASA Astrophysics Data System (ADS)

The Hilbert-Huang transform is a novel, adaptive approach to time series analysis that does not make assumptions about the data form. Its adaptive, local character allows the decomposition of nonstationary signals with high time-frequency resolution but also renders it susceptible to degradation from noise. We show that complementing the Hilbert-Huang transform with techniques such as zero-phase filtering, kernel density estimation and Fourier analysis allows it to be used effectively to detect and characterize signals with low signal-to-noise ratios.

Stroeer, Alexander; Cannizzo, John K.; Camp, Jordan B.; Gagarin, Nicolas

2009-06-01

22

Distinction of two different nonstationary signals with Hilbert-Huang transform  

NASA Astrophysics Data System (ADS)

In order to distinguish the difference of non-stationary signals, the novel time-frequency analysis approach, i.e. Hilbert- Huang transform (HHT), is applied in this paper. Firstly, Hilbert-Huang transform is briefly introduced. Secondly, two different non-stationary signals are described in Empirical Mode Decomposition (EMD) and Hilbert spectra. With these results, the two signals that looked apparently similar in time waves are distinctly different from each other. It is proved that HHT is effective for the purpose of distinction of non-stationary signals.

Han, Qingkai; Zhang, Shuai; Yang, Yong; Qu, Yanhuai; Wen, Bangchun

2009-12-01

23

Methods for detection and characterization of signals in noisy data with the Hilbert-Huang transform  

SciTech Connect

The Hilbert-Huang transform is a novel, adaptive approach to time series analysis that does not make assumptions about the data form. Its adaptive, local character allows the decomposition of nonstationary signals with high time-frequency resolution but also renders it susceptible to degradation from noise. We show that complementing the Hilbert-Huang transform with techniques such as zero-phase filtering, kernel density estimation and Fourier analysis allows it to be used effectively to detect and characterize signals with low signal-to-noise ratios.

Stroeer, Alexander; Cannizzo, John K.; Camp, Jordan B.; Gagarin, Nicolas [Laboratory for Gravitational Physics, Goddard Space Flight Center, Greenbelt, Maryland 20771 (United States); Starodub, Incorporated, 3504 Littledale Road, Kensington, Maryland, 20895 (United States)

2009-06-15

24

Gear Fault Detection Based on Ensemble Empirical Mode Decomposition and Hilbert-Huang Transform  

Microsoft Academic Search

A new approach to fault diagnosis of gear crack based on ensemble empirical mode decomposition (EEMD) and Hilbert-Huang transform (HHT) technique is presented. Firstly, the time-domain vibration signal of the gearbox with gear crack fault is measured. Then the original vibration signal is separated into intrinsic oscillation modes, using the ensemble empirical mode decomposition. Secondly, Hilbert transform tracks the modulation

Shufeng Ai; Hui Li

2008-01-01

25

Evaluation on the Influencing Factors of Agricultural Land Productivity in Huang-Huai Plain, China  

Microsoft Academic Search

Taking Huang-Huai Plain as an example, evaluation index system is established from four aspects, including the resources condition, the social and economic condition, the agricultural science and technology condition, and the disaster resistant and sustainable production condition. Correlation coefficient method and expert consultation method are used to determine the weight of evaluation index. After the standardization of extreme value, weighted

Yan-Hua Song; Guo-Qiang Wang

2010-01-01

26

Fault diagnosis of bearing oil whirl by Hilbert-Huang transmation  

Microsoft Academic Search

In actural measurement, it is difficult to find the useful signal among background noise. This paper suggests a new method to pick up signals and find fault information by using Hilbet Huang Transmation. In signal processing, at first small wave transmation was used as low-pass filter, thus part of noise can be filtrated. Then some of intrinsic mode functions have

Kai Wang; Guangpeng Zhang; Yumei Huang

2011-01-01

27

[Professor Wu Bing-huang's experiences in acupuncture treatment of facial paralysis].  

PubMed

Professor WU Bing-huang's unique experiences in acupuncture treatment of facial paralysis are introduced. He excellently uses anatomical and pathological knowledge of facial nerves, selecting acupoints according to nervous distribution, selecting needling methods according to the nervous trend, selecting acupuncture stimulation amount according to pathological changes and judging prognosis according to affected position. PMID:18447227

Huang, Dong-e; Wu, Qiang; Chen, Chuan-jiang

2008-03-01

28

Detection of involuntary human hand motions using Empirical Mode Decomposition and Hilbert-Huang Transform  

Microsoft Academic Search

Involuntary human hand motions, or tremors, are normally regarded as a non-stationary process. Traditional analysis methods approximate tremor signals as stationary processes. In this paper, we present a novel tremor detection method using Empirical Mode Decomposition (EMD) and Hilbert-Huang Transform (HHT). The results are expected to be helpful for real-time tremor suppression.

James Z. Zhang; Brant T. Price; Robert D. Adams; Kenneth Burbank; Theodore J. Knaga

2008-01-01

29

Application of Hilbert-Huang Transform for the determination of instantaneous low frequency of Plasma waves  

NASA Astrophysics Data System (ADS)

Downstream of a quasi-perpendicular bow shock of the Earth, various wave modes associated with the different boundaries have been confirmed and different methods have been used to find frequency and instantaneous frequency of the different modes. We applied Hilbert-Huang Transform in the determination of instantaneous frequency by decomposing the data observed by in-situ spacecraft in certain region in space called the Magnetosheath into intrinsic mode functions (IMFs) using empirical mode decomposition (EMD) technique of Huang et al., 1998. Instantaneous frequencies for the different IMFs were computed using Hilbert transform. The determined instantaneous frequency supports the non-stationary and non-linear nature of the data. The instantaneous wave vector was then computed. The observed data were taken from FGM instrument on Cluster II mission which provides 3-dimensional advantage for this analysis, and the results compared with the instantaneous frequency computed using simple Hilbert transform with electric field measurements of Cluster II mission already carried out.

Nathaniel, Ekong; Beloff, Natasha; Buckley, Andrew

2009-11-01

30

Ensemble empirical mode decomposition and Hilbert-Huang transform applied to bearing fault diagnosis  

Microsoft Academic Search

A signal analysis technique for bearing fault diagnosis based on ensemble empirical mode decomposition (EEMD) and Hilbert-Huang transform (HHT) is presented. EEMD can adaptively decompose vibration signal into a series of zero mean Amplitude Modulation-Frequency Modulation (AM-FM) Intrinsic Mode Functions (IMFs) without mode mixing. Hilbert transform tracks the modulation energy of the interesting Intrinsic Mode Functions (IMFs) and estimates the

Hui Li; Yucai Wang; Yanfang Ma

2010-01-01

31

Modal identification based on Hilbert-Huang Transform of structural response with SVD preprocessing  

NASA Astrophysics Data System (ADS)

In recent years, Empirical mode decomposition and Hilbert spectral analysis have been combined to identify system parameters. Singular-Value Decomposition is proposed as a signal preprocessing technique of Hilbert-Huang Transform to extract modal parameters for closely spaced modes and low-energy components. The proposed method is applied to a simulated airplane model built in Automatic Dynamic Analysis of Mechanical Systems software. The results demonstrate that the identified modal parameters are in good agreement with the baseline model.

Zheng, Min; Shen, Fan; Dou, Yuping; Yan, Xiaoyan

2009-12-01

32

Study on village pattern evolution in the middle region of Huang-Huai-Hai plain  

Microsoft Academic Search

Based on the data obtained from face-to-face interview and the measurements using global positioning system (GPS) and geographical information system (GIS) technology, the village pattern evolution of the WL village in the middle of the Huang-Huai-Hai plain was studied. The main results are shown as follows. Firstly, the WL village goes through a series of evolution pattern including the absolute

Lingling Yuan; Yuanqing He; Wenheng Wu; Gang Li; Zhen Yang

2007-01-01

33

[Characteristics of precipitation pH and conductivity at Mt. Huang].  

PubMed

To understand the general characteristics of pH distribution and pollution in precipitation at Mt. Huang, statistical analyses were conducted for the routine measurements of pH and conductivity (K) at Mt. Huang during 2006-2011. The results showed that: (1) Over the period of study, the annual volume weighted mean (VWM) precipitation pH varied from 4.81 to 5.57, with precipitation acidity strengthening before 2009 and weakening thereafter. The precipitation acidity showed evident seasonal variations, with the VWM pH lowest in winter (4.78), and highest in summer (5.33). The occurrence frequency of acid rain was 46% , accounting for 45% of total rainfalls and with the most frequent pH falling into weak acid to neutral rain. (2) The annual VWM K varied from 16.91 to 27.84 microS x cm(-1), with no evident trend. As for ions pollution, the precipitation was relatively clean at Mt. Huang, with the most frequent K range being below 15 microS x cm(-1), followed by 15-25 microS x cm(-1). From February 2010 to December 2011, precipitation samples were collected on daily basis for ions analysis, as well as pH and K measurement in lab. Detailed comparisons were conducted between the two sets of pH and K, one set from field measurement and the other from lab measurement. The results indicated: (1) The lab measured pH (K) was highly correlated with the field pH (K); however, the lab pH tended to move towards neutral comparing with the corresponding field pH, and the shift range was closely correlated with the field pH and rainfall. The shift range of K from field to lab was highly correlated with the total ion concentration of precipitation. The field K showed evident negative correlation with the field pH with a correlation coefficient of -0.51. (2) When sampling with nylon-polyethylene bags, the statistics showed smaller bias between two sets of pH, with higher correlation coefficient between two sets of K. Furthermore, the lab K also showed evident negative correlation with the lab pH. Comparing with the observations at other alpine sites in central to eastern China, the natural precipitation at Mt. Huang was weaker in acidity and contains lower ion concentration. PMID:23914555

Shi, Chun-e; Deng, Xue-liang; Wu, Bi-wen; Hong, Jie; Zhang, Su; Yang, Yuan-jian

2013-05-01

34

Application of the Hilbert-Huang transform to the search for gravitational waves  

SciTech Connect

We present the application of a novel method of time-series analysis, the Hilbert-Huang transform, to the search for gravitational waves. This algorithm is adaptive and does not impose a basis set on the data, and thus the time-frequency decomposition it provides is not limited by time-frequency uncertainty spreading. Because of its high time-frequency resolution it has important applications to both signal detection and instrumental characterization. Applications to the data analysis of the ground and space based gravitational wave detectors, LIGO and LISA, are described.

Camp, Jordan B.; Cannizzo, John K.; Numata, Kenji [Laboratory for Gravitational Physics, Goddard Space Flight Center, Greenbelt, Maryland 20771 (United States)

2007-03-15

35

Pulse transit time-based blood pressure estimation using hilbert-huang transform.  

PubMed

The pulse transit time (PTT) based method has been suggested as a continuous, cuffless and non-invasive approach to estimate blood pressure. It is of paramount importance to accurately determine the pulse transit time from the measured electrocardiogram (ECG) and photoplethysmo-gram (PPG) signals. We apply the celebrated Hilbert-Huang Transform (HHT) to process both the ECG and PPG signals, and improve the accuracy of the PTT estimation. Further, the blood pressure variation is obtained by using a well-established formula reflecting the relationship between the blood pressure and the estimated PTT. Simulation results are provided to illustrate the effectiveness of the proposed method. PMID:19964558

Zhang, Qiao; Shi, Yang; Teng, Daniel; Dinh, Anh; Ko, Seok-Bum; Chen, Li; Basran, Jenny; Dal Bello-Haas, Vanina; Choi, Younhee

2009-01-01

36

Hilbert-Huang Transform Analysis of Hydrological and Environmental Time Series  

NASA Astrophysics Data System (ADS)

Climatic and hydrologic time series often display periodicities, and thus Fourier spectral analysis sometimes is appropriate. However, time series that are nonstationary, and also perhaps nonlinear, are not well handled by standard Fourier spectral analysis. Methods to handle nonstationarity, such as moving-time-window Fourier spectral analysis, assume linearity and have known limitations regarding the combined frequency and time resolution. For example, if the time series is stationary, then it is well known that better frequency resolution can be achieved by observing a longer time series (more time points). However, if the time series is nonstationary, then shorter time windows are required to estimate the “local in time” spectrum, analogous to using short-memory moving averages that use only the recent past few values to forecast the next value (P. Bloomfield, Fourier Analysis of Time Series: An Introduction, 2nd ed., John Wiley, 2000) because the mean value is changing over time. Therefore, in nonstationary time series analysis, there is a tension between the competing goals of time and frequency resolution. This tension is the reason that N. Huang et al. (Proc. R. Soc. A, 454, 903-995, 1998) introduced the Hilbert-Huang Transform (HHT) as an alternative to moving-time-window Fourier spectral analysis (Bloomfield, 2000).

Burr, Tom

2009-06-01

37

Potential ex vivo immunomodulatory effects of San-Huang-Xie-Xin-Tang and its component herbs on mice and humans  

Microsoft Academic Search

Aim of the studySan-Huang-Xie-Xin-Tang (SHXXT), an important Chinese medicine formula, contains Rhei Rhizoma (RR), Scutellariae Radix (SR) and Coptidis Rhizoma (CR). RR and SR are abundant in anthraquinone and flavonoid polyphenols. Pharmacokinetic study of SHXXT indicated that glucuronides were the predominant forms of polyphenols in rats.

Chia-Yang Li; Yu-Chi Hou; Pei-Dawn Lee Chao; Chi-Sheng Shia; Ian C. Hsu; Shih-Hua Fang

2010-01-01

38

Climate change impacts on agriculture and soil carbon sequestration potential in the Huang-Hai Plain of China  

Microsoft Academic Search

For thousands of years, the Huang-Hai Plain in northeast China has been one of the most productive agricultural regions of the country. The future of this region will be determined in large part by how global climatic changes impact regional conditions and by actions taken to mitigate or adapt to climate change impacts. One potential mitigation strategy is to promote

Allison M. Thomson; R Cesar C. Izaurralde; Norman J. Rosenberg; Xiaoxia He

2006-01-01

39

Ephedrine-type alkaloid content of nutritional supplements containingephedra sinica (ma-huang) as determined by high performance liquid chromatography  

Microsoft Academic Search

Nutritional supplements containing Ephedra sinica (ma- huang), a botanical source of ephedrine-type alkaloids, have been linked to numerous episodes of ephedrine (EPH) toxicity. With passage of the 1994 Dietary Supplement Health and Education Act, nutritional supplements are no longer subject to the same FDA preapproval requirements as food additives, prescription, or nonpre- scription medications. As a consequence, EPH content is

B. J. Gurley; P. Wang; S. F. Gardner

1998-01-01

40

Surface layer similarity in the nocturnal boundary layer: the application of Hilbert-Huang transform  

NASA Astrophysics Data System (ADS)

Turbulence statistics such as flux-variance relationship are critical information in measuring and modeling ecosystem exchanges of carbon, water, energy, and momentum at the biosphere-atmosphere interface. Using a recently proposed mathematical technique, the Hilbert-Huang transform (HHT), this study highlights its possibility to quantify impacts of non-turbulent flows on turbulence statistics in the stable surface layer. The HHT is suitable for the analysis of non-stationary and intermittent data and thus very useful for better understanding the interplay of the surface layer similarity with complex nocturnal environment. Our analysis showed that the HHT can successfully sift non-turbulent components and be used as a tool to estimate the relationships between turbulence statistics and atmospheric stability in complex environments such as nocturnal stable boundary layer.

Hong, J.; Kim, J.; Ishikawa, H.; Ma, Y.

2010-04-01

41

Quantitative Local Atomic Displacements from Huang Scattering Normalized by Thermal Diffuse Scattering  

NASA Astrophysics Data System (ADS)

The three-dimensional (3-D) pattern of atomic displacements at the core of a small defect or defect cluster embedded in a bulk crystal is possible to measure in principle, but difficult to obtain in practice, especially if quantitative displacements are desired. Here, it is demonstrated that a least-squares fit to the single-crystal X-ray Huang-scattering distribution surrounding an intense Bragg peak is a practical means of obtaining quantitative displacements when thermal diffuse scattering is used as an internal intensity standard. After fitting a model based on local Kanzaki forces embedded within an elastic continuum, the use of finite-defect and point-defect methods of computing and interpreting the pattern of local displacements are compared and contrasted. To make the analysis general with regard to both crystal symmetry and defect symmetry, numerical Fourier transforms are employed rather than pursuing analytical expressions for the displacements.

Campbell, Branton J.

2010-05-01

42

Periodicity of flare index revisited using the Hilbert-Huang transform method  

NASA Astrophysics Data System (ADS)

Using the Hilbert-Huang Transform (HHT) method, we investigate the periodicity in the monthly mean flare indices from 1966 to 2007 (corresponding to almost four complete solar cycles), calculated by T. Atac and A. Ozguc. The results show as following. (1) The periods of 9.37 ± 2.53, 11.8 ± 0.172 and 23.6 ± 0.316 years are found to be statistically significant in the flare index. The most eminent period is 9.37 ± 2.53 years. (2) Other periods of 0.237 ± 0.196 years (86.6 ± 71.6 days), 0.525 ± 0.0508 years (191 ± 18.5 days), 1.05 ± 0.478 years (383 ± 174 days) and 2.37 ± 0.395 years are below the 99% confidence level line, suggesting they are due to stochastic random noise.

Gao, P. X.; Liang, H. F.; Zhu, W. W.

2011-04-01

43

Surface layer similarity in the nocturnal boundary layer: the application of Hilbert-Huang transform  

NASA Astrophysics Data System (ADS)

Turbulence statistics such as flux-variance relationship is critical information in measuring and modeling carbon, water, energy, and momentum exchanges at the biosphere-atmosphere interface. Using a recently proposed mathematical technique, the Hilbert-Huang transform (HHT), this study highlights its possibility to quantify impacts of non-turbulent flows on turbulence statistics in the stable surface layer. The HHT is suitable for the analysis of non-stationary and intermittent data and thus very useful for better understanding of the interplay of the surface layer similarity with complex nocturnal environment. Our analysis showed that the HHT can successfully sift non-turbulent components and be used as a tool to estimate the relationships between turbulence statistics and atmospheric stability in complex environment such as nocturnal stable boundary layer.

Hong, J.; Kim, J.; Ishikawa, H.; Ma, Y.

2009-10-01

44

Fluorescence line-narrowing difference spectra: Dependence of Huang-Rhys factor on excitation wavelength  

NASA Astrophysics Data System (ADS)

It is well known that fluorescence line narrowed (FLN) difference spectra (?FLN spectra) reduce to single-site fluorescence line shape function in the low-fluence limit. This finding is confirmed by the observation of different line shapes of FLN and ?FLN spectra obtained for pyrene (Py) in ethanol glass at various excitation wavelengths using time-resolved fluorescence measurements. A peculiar dependence of the Huang-Rhys factor (S) on excitation wavelength was discovered, and discussed in terms of the solute-solvent, intermolecular Lennard-Jones potential. A V-shaped frequency dependence of the S-factor suggests that the repulsive-dispersive potential is not sufficient to account for a complex 'color effect'.

Lin, Chen; Renge, Indrek; Jankowiak, Ryszard

2013-06-01

45

An herbal supplement containing Ma Huang-Guarana for weight loss: a randomized, double-blind trial  

Microsoft Academic Search

OBJECTIVE: To examine in overweight humans the short-term safety and efficacy for weight loss of an herbal supplement containing Ma Huang, Guarana and other ingredients.DESIGN: An 8 week randomized, double-blind placebo controlled study of a herbal dietary supplement (72 mg\\/day ephedrine alkaloids and 240 mg\\/day caffeine).SUBJECTS: Overweight men and women (body mass index, ?29 and ?35 kg\\/m2).MEASUREMENTS: The primary outcome

CN Boozer; JA Nasser; SB Heymsfield; V Wang; G Chen; JL Solomon

2001-01-01

46

Microbial diversity analysis of fermented mung beans (Lu-Doh-Huang) by using pyrosequencing and culture methods.  

PubMed

In Taiwanese alternative medicine Lu-doh-huang (also called Pracparatum mungo), mung beans are mixed with various herbal medicines and undergo a 4-stage process of anaerobic fermentation. Here we used high-throughput sequencing of the 16S rRNA gene to profile the bacterial community structure of Lu-doh-huang samples. Pyrosequencing of samples obtained at 7 points during fermentation revealed 9 phyla, 264 genera, and 586 species of bacteria. While mung beans were inside bamboo sections (stages 1 and 2 of the fermentation process), family Lactobacillaceae and genus Lactobacillus emerged in highest abundance; Lactobacillus plantarum was broadly distributed among these samples. During stage 3, the bacterial distribution shifted to family Porphyromonadaceae, and Butyricimonas virosa became the predominant microbial component. Thereafter, bacterial counts decreased dramatically, and organisms were too few to be detected during stage 4. In addition, the microbial compositions of the liquids used for soaking bamboo sections were dramatically different: Exiguobacterium mexicanum predominated in the fermented soybean solution whereas B. virosa was predominant in running spring water. Furthermore, our results from pyrosequencing paralleled those we obtained by using the traditional culture method, which targets lactic acid bacteria. In conclusion, the microbial communities during Lu-doh-huang fermentation were markedly diverse, and pyrosequencing revealed a complete picture of the microbial consortium. PMID:23700436

Chao, Shiou-Huei; Huang, Hui-Yu; Chang, Chuan-Hsiung; Yang, Chih-Hsien; Cheng, Wei-Shen; Kang, Ya-Huei; Watanabe, Koichi; Tsai, Ying-Chieh

2013-05-20

47

Microbial Diversity Analysis of Fermented Mung Beans (Lu-Doh-Huang) by Using Pyrosequencing and Culture Methods  

PubMed Central

In Taiwanese alternative medicine Lu-doh-huang (also called Pracparatum mungo), mung beans are mixed with various herbal medicines and undergo a 4-stage process of anaerobic fermentation. Here we used high-throughput sequencing of the 16S rRNA gene to profile the bacterial community structure of Lu-doh-huang samples. Pyrosequencing of samples obtained at 7 points during fermentation revealed 9 phyla, 264 genera, and 586 species of bacteria. While mung beans were inside bamboo sections (stages 1 and 2 of the fermentation process), family Lactobacillaceae and genus Lactobacillus emerged in highest abundance; Lactobacillus plantarum was broadly distributed among these samples. During stage 3, the bacterial distribution shifted to family Porphyromonadaceae, and Butyricimonas virosa became the predominant microbial component. Thereafter, bacterial counts decreased dramatically, and organisms were too few to be detected during stage 4. In addition, the microbial compositions of the liquids used for soaking bamboo sections were dramatically different: Exiguobacterium mexicanum predominated in the fermented soybean solution whereas B. virosa was predominant in running spring water. Furthermore, our results from pyrosequencing paralleled those we obtained by using the traditional culture method, which targets lactic acid bacteria. In conclusion, the microbial communities during Lu-doh-huang fermentation were markedly diverse, and pyrosequencing revealed a complete picture of the microbial consortium.

Chao, Shiou-Huei; Huang, Hui-Yu; Chang, Chuan-Hsiung; Yang, Chih-Hsien; Cheng, Wei-Shen; Kang, Ya-Huei; Watanabe, Koichi; Tsai, Ying-Chieh

2013-01-01

48

A novel analysis method for near infrared spectroscopy based on Hilbert-Huang transform  

NASA Astrophysics Data System (ADS)

Near Infrared Imager (NIRI) has been widely used to access the brain functional activity non-invasively. We use a portable, multi-channel and continuous-wave NIR topography instrument to measure the concentration changes of each hemoglobin species and map cerebral cortex functional activation. By extracting some essential features from the BOLD signals, optical tomography is able to be a new way of neuropsychological studies. Fourier spectral analysis provides a common framework for examining the distribution of global energy in the frequency domain. However, this method assumes that the signal should be stationary, which limits its application in non-stationary system. The hemoglobin species concentration changes are of such kind. In this work we develop a new signal processing method using Hilbert-Huang transform to perform spectral analysis of the functional NIRI signals. Compared with wavelet based multi-resolution analysis (MRA), we demonstrated the extraction of task related signal for observation of activation in the prefrontal cortex (PFC) in vision stimulation experiment. This method provides a new analysis tool for functional NIRI signals. Our experimental results show that the proposed approach provides the unique method for reconstructing target signal without losing original information and enables us to understand the episode of functional NIRI more precisely.

Zhou, Zhenyu; Yang, Hongyu; Liu, Yun; Ruan, Zongcai; Luo, Qingming; Gong, Hui; Lu, Zuhong

2007-05-01

49

An analysis method for magnetotelluric data based on the Hilbert-Huang Transform  

NASA Astrophysics Data System (ADS)

Prevailing methods of magnetotelluric (MT) data analysis determine the spectra using variations of the Fourier Transform (FT), which is based on the principle of signal stationarity. However, MT data series are non-stationary random signals that do not meet the basic requirements of conventional methods based on the FT. In recent years, the Hilbert-Huang Transform (HHT) has been regarded as a powerful tool for adaptive analysis of non-linear and non-stationary signals. This paper proposes for the first time the adoption of a new method of analysis for MT data, and focuses on two aspects that are facilitated by applying the HHT. The first aspect is the pretreatment of the MT time series data through selecting MT data subsets, and noise suppression; the other concerns the determination of the impedance and apparent resistivity using the HHT instantaneous spectrum. The conclusion reached through discussion of the first aspect is that the proposed methods can greatly improve the quality of MT data. The conclusion drawn from the second aspect is that the HHT instantaneous spectrum method can overcome the problems described above, and obtain stable and reliable estimation of the impedance tensor, and thus naturally minimise the estimation bias brought about by the non-stationary characteristics of MT data. Therefore, the HHT method is effective in analysing MT data and is able to generate meaningful geological information.

Cai, Jian-Hua; Tang, Jing-Tian; Hua, Xi-Rui; Gong, Yu-Rong

2009-06-01

50

NINJA data analysis with a detection pipeline based on the Hilbert-Huang transform  

NASA Astrophysics Data System (ADS)

The NINJA data analysis challenge allowed the study of the sensitivity of data analysis pipelines to binary black hole numerical relativity waveforms in simulated Gaussian noise at the design level of the LIGO observatory and the VIRGO observatory. We analyzed NINJA data with a pipeline based on the Hilbert-Huang transform, utilizing a detection stage and a characterization stage: detection is performed by triggering on excess instantaneous power, characterization is performed by displaying the kernel density enhanced (KD) time-frequency trace of the signal. Using the simulated data based on the two LIGO detectors, we were able to detect 77 signals out of 126 above signal-to-noise ratio, SNR 5 in coincidence, with 43 missed events characterized by SNR < 10. Characterization of the detected signals revealed the merger part of the waveform in high time and frequency resolution, free from time-frequency uncertainty. We estimated the timelag of the signals between the detectors based on the optimal overlap of the individual KD time-frequency maps, yielding estimates accurate within a fraction of a millisecond for half of the events. A coherent addition of the data sets according to the estimated timelag eventually was used in a final characterization of the event.

Stroeer, Alexander; Camp, Jordan

2009-06-01

51

Observations of cloud condensation nuclei in Mt. Huang: instrumentation and early observations  

NASA Astrophysics Data System (ADS)

A new commercial instrument for measuring Cloud Condensation Nuclei (CCN), the Droplet Measurement Technologies Cylindrical Continuous-Flow Streamwise Thermal Gradient CCN Chamber (CFSTGC), installed on Mount Huang meteorological station (30°19'N, 118°14'E, 1840m above sea level) from 16 April to 28 July 2008. This instrument can measure CCN concentrations at supersaturations from 0.1% to 2% (potentially up to 6%), as well as a 1 Hz sampling rate that is sufficient for ground-based or airborne platform operation. The instrument records data continuously at 1-second intervals 24 hours a day. For the 98-day, continuous study the average CCN concentration was found to range between a few hundred and a few thousand nuclei per cm3 at supersaturations between 0.3 and 1%. Diurnal variations were observed, as well as other possible influences, such as wind speed, wind direction and mixing depth. At a constant supersaturation of 0.5% the CCN concentration is typically on the order of 361 to 2297 nuclei per cm3. A description of the instrumentation and early observations are presented and discussed.

Chen, Kui; Yin, Yan; Chen, Chen; Yang, Weifeng; Deng, Wei; Hu, Zhenghua; Wu, Fangfang

2009-07-01

52

Study of the Lee-Huang-Yang correction for atomic bosons  

NASA Astrophysics Data System (ADS)

The famous Lee-Huang-Yang (LHY) term describes the first-order correction to the mean-field energy for strongly interacting bosons [1], yet it has only been detected with bosons composed of loosely bound fermion pairs [2,3]. Tan's universal relations, originally calculated for fermions [4], connect a property called the Contact to many macroscopic parameters of a quantum gas, such as its total energy. These relations have been verified experimentally for Fermi systems [5]. We apply these relations to a Bose gas to realize a unique tool to study the LHY correction. We perform RF spectroscopy on a BEC of ^85Rb close to a Feshbach resonance, and measure the strength of the RF lineshape tail which decays as 1/w^3/2. From this we extract the Contact, which increases as a function of the interaction strength. This allows us to quantitatively study the LHY term for atomic bosons, as well as investigate time-dependent effects that arise from the rate of change of the interaction strength compared to various experimental time scales.

Wild, Robert; Pino, Juan; Makotyn, Philip; Cornell, Eric; Jin, Deborah

2011-06-01

53

Damage detection in structures under traveling loads by Hilbert-Huang transform  

NASA Astrophysics Data System (ADS)

Hilbert-Huang transform (HHT) is an innovative data-processing technique for analyzing nonstationary and nonlinear signals. A novel HHT-based method for damage detection of bridge structures under a traveling load is proposed. The technique uses a single point measurement and is able to identify the presence and the location of the damage along the beam. The measured data are processed by the HHT technique, and none a priori information is needed about the response of the undamaged structure. Damage location is revealed by direct inspection of the first instantaneous frequency, which presents a sharp crest in correspondence of the damaged section. The identification capabilities of the proposed technique are studied varying the damage locations, crack depths and velocity of the moving load. The effect of ambient noise is also taken into account. Theoretical as well as numerical results show the identification is rather accurate, results are not very sensitive to the crack depth and ambient noise, while they are sensibly affected by the damage location and by the speed of the moving load as well. Theoretical analysis identifies a characteristic load velocity interval, depending both on the first natural frequency of the bridge and the damage location, within which the HHT can be successfully applied.

Roveri, N.; Carcaterra, A.

2012-04-01

54

Phase retrieval for noisy fringe pattern by using empirical mode decomposition and Hilbert Huang transform  

NASA Astrophysics Data System (ADS)

To address the issue of the intermittent noise in optical fringe pattern, an adaptive method of noise reduction is given based on empirical mode decomposition (EMD) and Hilbert Huang transform (HHT), and then the wrapped phase is obtained by performing the Hilbert transform on the refined pattern. Firstly, the signal of the fringe pattern is decomposed into several intrinsic mode functions (IMFs). With the instantaneous frequencies and marginal spectra of each IMF obtained by HHT, the criterion of identifying the noise IMF is determined. Then, it is judged whether a mode-mixing problem, which is the frequent problem in traditional EMD, appears in each noise IMF. If the problem appears, the ``noise,'' which is designed according to the signal adaptively, is added to the original signal, and then the obtained new signal is decomposed again. The process will be repeated until there is no mode mixing in the noise IMF. Finally, the wrapped phase is obtained by performing a Hilbert transform on the refined pattern with noise and background components removed. The proposed method can solve the mode-mixing problem effectively. It can reduce most of the noise and maintain a large amount of detailed phase information simultaneously. Simulation and compared experiments show the efficiency, robustness, and accuracy of the proposed method.

Wang, Chenxing; Da, Feipeng

2012-06-01

55

Lagrangian single-particle turbulent statistics through the Hilbert-Huang transform  

NASA Astrophysics Data System (ADS)

The Hilbert-Huang transform is applied to analyze single-particle Lagrangian velocity data from numerical simulations of hydrodynamic turbulence. The velocity trajectory is described in terms of a set of intrinsic mode functions Ci(t) and of their instantaneous frequency ?i(t). On the basis of this decomposition we define the ?-conditioned statistical moments of the Ci modes, named q-order Hilbert spectra (HS). We show that such quantities have enhanced scaling properties as compared to traditional Fourier transform- or correlation-based (structure functions) statistical indicators, thus providing better insights into the turbulent energy transfer process. We present clear empirical evidence that the energylike quantity, i.e., the second-order HS, displays a linear scaling in time in the inertial range, as expected from a dimensional analysis. We also measure high-order moment scaling exponents in a direct way, without resorting to the extended self-similarity procedure. This leads to an estimate of the Lagrangian structure function exponents which are consistent with the multifractal prediction in the Lagrangian frame as proposed by Biferale [Phys. Rev. Lett.PRLTAO0031-900710.1103/PhysRevLett.93.064502 93, 064502 (2004)].

Huang, Yongxiang; Biferale, Luca; Calzavarini, Enrico; Sun, Chao; Toschi, Federico

2013-04-01

56

Lagrangian single-particle turbulent statistics through the Hilbert-Huang transform.  

PubMed

The Hilbert-Huang transform is applied to analyze single-particle Lagrangian velocity data from numerical simulations of hydrodynamic turbulence. The velocity trajectory is described in terms of a set of intrinsic mode functions C(i)(t) and of their instantaneous frequency ?(i)(t). On the basis of this decomposition we define the ?-conditioned statistical moments of the C(i) modes, named q-order Hilbert spectra (HS). We show that such quantities have enhanced scaling properties as compared to traditional Fourier transform- or correlation-based (structure functions) statistical indicators, thus providing better insights into the turbulent energy transfer process. We present clear empirical evidence that the energylike quantity, i.e., the second-order HS, displays a linear scaling in time in the inertial range, as expected from a dimensional analysis. We also measure high-order moment scaling exponents in a direct way, without resorting to the extended self-similarity procedure. This leads to an estimate of the Lagrangian structure function exponents which are consistent with the multifractal prediction in the Lagrangian frame as proposed by Biferale et al. [Phys. Rev. Lett. 93, 064502 (2004)]. PMID:23679366

Huang, Yongxiang; Biferale, Luca; Calzavarini, Enrico; Sun, Chao; Toschi, Federico

2013-04-22

57

Detection of the third and fourth heart sounds using Hilbert-Huang transform  

PubMed Central

Background The third and fourth heart sound (S3 and S4) are two abnormal heart sound components which are proved to be indicators of heart failure during diastolic period. The combination of using diastolic heart sounds with the standard ECG as a measurement of ventricular dysfunction may improve the noninvasive diagnosis and early detection of myocardial ischemia. Methods In this paper, an adaptive method based on time-frequency analysis is proposed to detect the presence of S3 and S4. Heart sound signals during diastolic periods were analyzed with Hilbert-Huang Transform (HHT). A discrete plot of maximal instantaneous frequency and its amplitude was generated and clustered. S3 and S4 were recognized by the clustered points, and performance of the method was further enhanced by period definition and iteration tracking. Results Using the proposed method, S3 and S4 could be detected adaptively in a same method. 90.3% of heart sound cycles with S3 were detected using our method, 9.6% were missed, and 9.6% were false positive. 94% of S4 were detected using our method, 5.5% were missed, and 16% were false positive. Conclusions The proposed method is adaptive for detecting low-amplitude and low-frequency S3 and S4 simultaneously compared with previous detection methods, which would be practical in primary care.

2012-01-01

58

Hilbert-Huang transform analysis of dynamic and earthquake motion recordings  

USGS Publications Warehouse

This study examines the rationale of Hilbert-Huang transform (HHT) for analyzing dynamic and earthquake motion recordings in studies of seismology and engineering. In particular, this paper first provides the fundamentals of the HHT method, which consist of the empirical mode decomposition (EMD) and the Hilbert spectral analysis. It then uses the HHT to analyze recordings of hypothetical and real wave motion, the results of which are compared with the results obtained by the Fourier data processing technique. The analysis of the two recordings indicates that the HHT method is able to extract some motion characteristics useful in studies of seismology and engineering, which might not be exposed effectively and efficiently by Fourier data processing technique. Specifically, the study indicates that the decomposed components in EMD of HHT, namely, the intrinsic mode function (IMF) components, contain observable, physical information inherent to the original data. It also shows that the grouped IMF components, namely, the EMD-based low- and high-frequency components, can faithfully capture low-frequency pulse-like as well as high-frequency wave signals. Finally, the study illustrates that the HHT-based Hilbert spectra are able to reveal the temporal-frequency energy distribution for motion recordings precisely and clearly.

Zhang, R. R.; Ma, S.; Safak, E.; Hartzell, S.

2003-01-01

59

Application of Hilbert-Huang transform based instantaneous frequency to seismic reflection data  

NASA Astrophysics Data System (ADS)

Empirical mode decomposition (EMD) is designed to decompose non-stationary, nonlinear data into a series of intrinsic mode functions (IMFs) adaptively. This procedure is automatic, data-driven and time-variant. And then a Hilbert transform is applied to these IMFs. The combination of EMD with a Hilbert transform is known as Hilbert-Huang transform (HHT). HHT can be used to calculate meaningful multi-resolution instantaneous frequency (HHT based instantaneous frequency). Currently, the application of EMD and HHT to seismic data is performed mainly for noise attenuation. In this paper, we demonstrate new insights of EMD and HHT to seismic data analysis. We first extend the research of Flandrin et al. and analyze how EMD behaves on a Gaussian band-pass signal; we then employ HHT based instantaneous frequency on wedge model and real seismic data to delineate thickness variations. Numerical examples of Gaussian band-pass noise indicate that EMD acts as an adaptive, multi-band overlapping filter bank. The analysis of a wedge model and 2D real seismic data illustrates that HHT based instantaneous frequency is more effective than conventional Hilbert transform based instantaneous frequency in delineating the thickness variation of seismic thin bed.

Zhou, Yanhui; Chen, Wenchao; Gao, Jinghuai; He, Yongqiang

2012-07-01

60

Multimodal Pressure Flow Analysis: Application of Hilbert Huang Transform in Cerebral Blood Flow Regulation  

PubMed Central

Quantification of nonlinear interactions between two nonstationary signals presents a computational challenge in different research fields, especially for assessments of physiological systems. Traditional approaches that are based on theories of stationary signals cannot resolve nonstationarity-related issues and, thus, cannot reliably assess nonlinear interactions in physiological systems. In this review we discuss a new technique “Multi-Modal Pressure Flow method (MMPF)” that utilizes Hilbert-Huang transformation to quantify dynamic cerebral autoregulation (CA) by studying interaction between nonstationary cerebral blood flow velocity (BFV) and blood pressure (BP). CA is an important mechanism responsible for controlling cerebral blood flow in responses to fluctuations in systemic BP within a few heart-beats. The influence of CA is traditionally assessed from the relationship between the well-pronounced systemic BP and BFV oscillations induced by clinical tests. Reliable noninvasive assessment of dynamic CA, however, remains a challenge in clinical and diagnostic medicine. In this brief review we: 1) present an overview of transfer function analysis (TFA) that is traditionally used to quantify CA; 2) describe the a MMPF method and its modifications; 3) introduce a newly developed automatic algorithm and engineering aspects of the improved MMPF method; and 4) review clinical applications of MMPF and its sensitivity for detection of CA abnormalities in clinical studies. The MMPF analysis decomposes complex nonstationary BP and BFV signals into multiple empirical modes adaptively so that the fluctuations caused by a specific physiologic process can be represented in a corresponding empirical mode. Using this technique, we recently showed that dynamic CA can be characterized by specific phase delays between the decomposed BP and BFV oscillations, and that the phase shifts are significantly reduced in hypertensive, diabetics and stroke subjects with impaired CA. In addition, the new technique enables reliable assessment of CA using both data collected during clinical test and spontaneous BP/BFV fluctuations during baseline resting conditions.

Lo, Men-Tzung; Hu, Kun; Liu, Yanhui; Peng, C.-K.; Novak, Vera

2008-01-01

61

Interdependence between damage indices and ground motion parameters based on Hilbert-Huang transform  

NASA Astrophysics Data System (ADS)

Feature extraction from seismic accelerograms is a key issue in characterization of earthquake damage in structures. Until today, a number of effective classical parameters such as peak ground acceleration (PGA) and Arias intensity have been proposed for analyzing the earthquake motion records. The aim of this paper is to search for new crucial characteristic seismic parameters which provide information pertinent to the damage indicators of the structures. The first proposed parameter is the maximum amplitude (AHHT_max) and the second is the mean amplitude (AHHT_mean). Emphasis of our work has been placed on the use of the Hilbert-Huang transform (HHT). A set of 13 natural accelerograms from worldwide well-known sites with strong seismic activity have been used. The HHT has been applied to the nonlinear and non-stationary data (earthquake recordings). Each complex seismic accelerogram is decomposed into several simple components called intrinsic mode functions (IMFs). Using the IMFs a three-dimensional time-frequency distribution of earthquake excitation is computed and two new seismic parameters are proposed and evaluated. After the numerical computation of all the seismic parameters (classical and proposed), nonlinear dynamic analysis is carried out to provide the post-seismic damage status of the structure under study. Two structural damage indices are utilized and the degree of interrelation among them and the seismic parameters is provided by correlation coefficients. Furthermore, two different reinforced concrete structures are examined. Results indicate the high correlation of the new seismic parameters (AHHT_max, AHHT_mean) with the damage indices and confirm that HHT is a promising tool for extracting information to characterize damage in structures.

Alvanitopoulos, P. F.; Andreadis, I.; Elenas, A.

2010-02-01

62

Monitoring vegetation cover change using time series of remote sensing data in Huang-Huai-Hai Plain, China  

NASA Astrophysics Data System (ADS)

Time series of remote sensing data is widely used in vegetation change monitoring in regions of great environmental changes. In this paper, GIMMS dataset is used to extract temporal and spatial patterns of vegetation cover change in Huang-Huai-Hai Plain, China from 1993 to 2006. The results indicate that the total vegetation is increasing in this region. But the changing trend has spatial variations with some part improving and others deteriorating. The vegetation cover changed due to both human practices and climate changes.

Lu, Linlin; Guo, Huadong; Fu, Wenxue

2009-09-01

63

Study of nonlinear oscillations in a glow discharge plasma using empirical mode decomposition and Hilbert Huang transform  

NASA Astrophysics Data System (ADS)

Hilbert Huang transform (HHT) based time series analysis was carried out on nonlinear floating potential fluctuations obtained from hollow cathode glow discharge plasma in the presence of anode glow. HHT was used to obtain contour plots and the presence of nonlinearity was studied. Frequency shift with time, which is a typical nonlinear behaviour, was detected from the contour plots. Various plasma parameters were measured and the concepts of correlation coefficients and the physical contribution of each intrinsic mode function have been discussed. Physically important quantities such as instantaneous energy and their uses in studying physical phenomena such as intermittency and non-stationary data have also been discussed.

Wharton, A. M.; Sekar Iyengar, A. N.; Janaki, M. S.

2013-02-01

64

Differential impact of small-scaled tectonic movements on fluvial morphology and sedimentology (the Huang Shui catchment, NE Tibet Plateau)  

NASA Astrophysics Data System (ADS)

The aim of this paper is to investigate the morphological implications of the interplay between tectonic movements at different rates, timescales, and spatial extent in a catchment of intermediate size, the Huang Shui River (a main tributary of the Yellow River in the NE Tibet Plateau). River incision started from a peneplain-like surface that developed in post-Miocene-Pliocene times. At the end of the Tertiary, a general tectonic uplift of the Tibetan Plateau initiated river incision. This general uplift also caused local fragmentation of the Huang Shui catchment into blocks (kilometers or maximally, a few tens of kilometers) of local extent that have subsided and/or uplifted relative to one another. Fluvial deposition of > 30 m in the subsiding blocks contrasts with erosion and formation of gorges in the uplifted blocks. Incision into the former peneplain was not continuous but a staircase of terraces developed under climatic influences. Terrace deposits are sometimes capped by interglacial soils or soil-derived material. Apparently, terrace incision occurred at the transition to the next cold period. The different rates of uplift and subsidence of the individual blocks resulted in the simultaneous development of erosion and accumulation terraces of different sizes within the same catchment, even within the same tectonic block. This makes it impossible to connect the terraces of the different blocks, except for the three youngest terraces (representing the last 300,000 years), thus illustrating the uniform tectonic history of the catchment since that time.

Vandenberghe, J.; Wang, X.; Lu, H.

2011-11-01

65

Nonpigmenting solitary fixed drug eruption caused by a Chinese traditional herbal medicine, ma huang ( Ephedra Hebra), mainly containing pseudoephedrine and ephedrine  

Microsoft Academic Search

We describe a case of nonpigmenting solitary fixed drug eruption appearing on the right thigh of a 31-year-old woman in Japan. The causative drug was determined by closed patch test on postlesional skin as a Chinese traditional herbal medicine, ma huang (Ephedra Hebra), mainly containing pseudoephedrine and ephedrine. (J Am Acad Dermatol 2003;48:628-30.)

Kazuhiko Matsumoto; Hajime Mikoshiba; Toshiaki Saida

2003-01-01

66

Rub-impact fault vibration analysis of rotor system with the different parameters using Hilbert-Huang transform  

NASA Astrophysics Data System (ADS)

The vibration characteristics of a rub-impact rotor system with different parameters are investigated using Hil-bert-Huang Transform (HHT)-a relative novel time-frequency analysis method. Firstly, the rotor with rub-impact at fixed limiter is modeled by finite element method (FEM). Then, system simulation signals at different rotating speeds, rub-impact clearances and rub-impact rod stiffness are obtained based on the FE model, moreover which are analyzed by using HHT along with Fast Fourier Transform (FFT) and shaft center orbit methods. The results show that the effects of variables on system motion patterns, response properties and rub-impact severity differ in degrees. Some conclusions are achieved which may be useful to detect rub-impact fault accurately and effectively.

Yang, Yong; Zhang, Shuai; Han, Qingkai; Qu, Yanhuai

2009-12-01

67

On the origin of bistability in the Stage 2 of the Huang-Ferrell model of the MAPK signaling  

NASA Astrophysics Data System (ADS)

Mitogen-activated protein kinases (MAPKs) are important signal transducing enzymes, unique to eukaryotes, that are involved in many pathways of cellular regulation. Successive phosphorylation cascades mediated by MAPKs serve as sensitive switches initiating various cellular processes. Apart from this basic feature, the underlying reaction network is capable of displaying other nonlinear phenomena including bistable steady states and hysteresis as well as periodic oscillations. We show that from the mechanistic point of view, bistability is a consequence of interaction between single and double phosphorylation/dephosphorylation pathways in a Stage 2 subsystem of the Huang-Ferrell model. Within this subsystem we uncover the core subnetwork obtained by systematic reduction relying on the methods of stoichiometric network analysis. For the core model we show that there is either one stable steady state or three steady states of which two are stable and point out the role of interplay between the single and double phosphorylation subnetworks in generating bistability.

Hada?, O.; Schreiber, I.; P?ibyl, M.

2013-02-01

68

A Novel Preprocessing Method Using Hilbert Huang Transform for MALDI-TOF and SELDI-TOF Mass Spectrometry Data  

PubMed Central

Motivation Mass spectrometry is a high throughput, fast, and accurate method of protein analysis. Using the peaks detected in spectra, we can compare a normal group with a disease group. However, the spectrum is complicated by scale shifting and is also full of noise. Such shifting makes the spectra non-stationary and need to align before comparison. Consequently, the preprocessing of the mass data plays an important role during the analysis process. Noises in mass spectrometry data come in lots of different aspects and frequencies. A powerful data preprocessing method is needed for removing large amount of noises in mass spectrometry data. Results Hilbert-Huang Transformation is a non-stationary transformation used in signal processing. We provide a novel algorithm for preprocessing that can deal with MALDI and SELDI spectra. We use the Hilbert-Huang Transformation to decompose the spectrum and filter-out the very high frequencies and very low frequencies signal. We think the noise in mass spectrometry comes from many sources and some of the noises can be removed by analysis of signal frequence domain. Since the protein in the spectrum is expected to be a unique peak, its frequence domain should be in the middle part of frequence domain and will not be removed. The results show that HHT, when used for preprocessing, is generally better than other preprocessing methods. The approach not only is able to detect peaks successfully, but HHT has the advantage of denoising spectra efficiently, especially when the data is complex. The drawback of HHT is that this approach takes much longer for the processing than the wavlet and traditional methods. However, the processing time is still manageable and is worth the wait to obtain high quality data.

Wu, Li-Ching; Chen, Hsin-Hao; Horng, Jorng-Tzong; Lin, Chen; Huang, Norden E.; Cheng, Yu-Che; Cheng, Kuang-Fu

2010-01-01

69

Research into the Detonation of Ammonite PzhV-20 and Certain Other Explosives (Issledovanie Detonatsii Ammonita PzhV-20 I Nekotorykh Drugikh Vv).  

National Technical Information Service (NTIS)

Measurement of the parameters of the detonation wave (particle velocity behind the detonation front and others) constitutes an important factor in the determination of the detonation mechanism of commercial explosives. The so-called cut-off method of dete...

A. N. Dremin K. K. Shvedov V. A. Veretennikov

1969-01-01

70

Correlation of black carbon aerosol and carbon monoxide in the high-altitude environment of Mt. Huang in eastern China  

NASA Astrophysics Data System (ADS)

Understanding the relationship between black carbon (BC) and carbon monoxide (CO) will help improve BC emission inventories and the evaluation of global/regional climate forcing effects. In the present work, the BC (PM1) and CO mixing ratio was continuously measured at a high-altitude background station on the summit of Mt. Huang (30.16° N, 118.26° E, 1840 m a.s.l.). Annual mean BC concentration was 1004.5 ± 895.5 ng/m3 with maxima in spring and autumn. The yearly averaged CO concentration was 424.1 ± 159.2 ppbv. The BC-CO relationship was found to show different seasonal features but strong positive correlation (R > 0.8). In Mt. Huang area, the ?BC/?CO ratio showed unimodal diurnal variations and had a maximum during the day (0900-1700 LST) and minimum at night (2100-0400 LST) in all seasons, indicating the impact of planetary boundary layer and the intrusion of clean air masses from the high troposphere. Back trajectory cluster analysis showed that the ?BC/?CO ratio of plumes from the Eastern China (Jiangsu, Zhejiang provinces and Shanghai) was 8.8 ± 0.9 ng/m3/ppbv. Transportation and industry were deemed as controlling factors of the BC-CO relationship in this region. The ?BC/?CO ratios for air masses from northern China (Anhui, Henan, Shanxi and Shandong provinces) and southern China (Jiangxi, Fujian and Hunan provinces) were quite similar with mean values of 6.5 ± 0.4 and 6.5 ± 0.2 ng/m3/ppbv, respectively. The case studies combined with satellite observations demonstrated that the ?BC/?CO ratio for biomass burning (BB) plume was 10.3±0.3~11.6±0.5ng/m3/ppbv. The ?BC/?CO-RH relationship showed that BC particles from Eastern China was much more easily removed from atmosphere than other inland regions due to the higher RH along transport pathway, implying the importance of chemical compositions and mixing states on BC residence time in the atmosphere.

Xiaole, P.; Kanaya, Y.; Wang, Z.

2011-12-01

71

Correlation of black carbon aerosol and carbon monoxide in the high-altitude environment of Mt. Huang in Eastern China  

NASA Astrophysics Data System (ADS)

Understanding the relationship between black carbon (BC) and carbon monoxide (CO) will help improve BC emission inventories and the evaluation of global/regional climate forcing effects. In the present work, the BC (PM1) mass concentration and CO mixing ratio were continuously measured at a high-altitude background station on the summit of Mt. Huang (30.16° N, 118.26° E, 1840 m a.s.l.). Annual mean BC mass concentration was 1004.5 ± 895.5 ng m-3 with maxima in spring and autumn, and annual mean CO mixing ratio was 424.1 ± 159.2 ppbv. A large increase of CO was observed in the cold season, implying the contribution from the large-scale domestic coal/biofuel combustion for heating. The BC-CO relationship was found to show different seasonal features but strong positive correlation (R>0.8). In Mt. Huang area, the ?BC/?CO ratio showed unimodal diurnal variations and had a maximum during the day (09:00-17:00 LST) and minimum at night (21:00-04:00 LST) in all seasons, indicating the impact of planetary boundary layer and the intrusion of clean air masses from the high troposphere. Back trajectory cluster analysis showed that the ?BC/?CO ratio of plumes from the Eastern China (Jiangsu, Zhejiang provinces and Shanghai) was 8.8 ± 0.9 ng m-3 ppbv-1. Transportation and industry were deemed as controlling factors of the BC-CO relationship in this region. The ?BC/?CO ratios for air masses from Northern China (Anhui, Henan, Shanxi and Shandong provinces) and southern China (Jiangxi, Fujian and Hunan provinces) were quite similar with mean values of 6.5 ± 0.4 and 6.5 ± 0.2 ng m-3 ppbv-1 respectively. The case studies combined with satellite observations demonstrated that the ?BC/?CO ratio for biomass burning (BB) plumes were 10.3 ± 0.3 and 11.6 ± 0.5ng m-3 ppbv-1, significantly higher than those during non-BB impacted periods. The loss of BC during transport was also investigated on the basis of the ?BC/?CO-RH (relative humidity) relationship along air mass pathways. The results showed that BC particles from Eastern China area was much more easily removed from atmosphere than other inland regions due to the higher RH along transport pathway, implying the importance of chemical compositions and mixing states on BC residence time in the atmosphere.

Pan, X. L.; Kanaya, Y.; Wang, Z. F.; Liu, Y.; Pochanart, P.; Akimoto, H.; Sun, Y. L.; Dong, H. B.; Li, J.; Irie, H.; Takigawa, M.

2011-09-01

72

Multi-criteria decision analyses. Viewing MCDA in terms of both process and aggregation methods: some thoughts, motivated by the paper of Huang, Keisler and Linkov.  

PubMed

The paper of Huang, Keisler and Linkov (HKL) (Huang et al., 2011) has motivated us to this note about the relation between ranking procedures and Multi-Criteria Decision Analysis (MCDA) tools. The key concept in the HKL-paper is in our eyes the 'trade-off'. A 'trade-off' seems necessary, when conflicting indicator values are present. HKL stress that the general application of MCDA is hampered by different terminology. We do not claim to have a solution for that problem. Nevertheless, we think that the discussion is worthwhile and this note presents some of our ideas, which basically imply the need of a broadening of the definition of MCDA. PMID:22475219

Bruggemann, Rainer; Carlsen, Lars

2012-04-03

73

Application of Hilbert-Huang transform to characterize soil liquefaction and quay wall seismic responses modeled in centrifuge shaking-table tests  

Microsoft Academic Search

In this paper, a Hilbert-Huang Transform data-processing technique is successfully used to characterize the seismic responses of soil–quay wall systems using measured data in a series of geotechnical centrifuge shaking-table tests. The predominant frequency of a liquefied deposit shifts down to a low frequency level; however, “de-liquefaction” leads to frequent, local higher-frequency spikes in the time histories of predominant instantaneous

Yu-Chen Wei; Chung-Jung Lee; Wen-Yi Hung; Huei-Tsyr Chen

2010-01-01

74

Evaluation of the Hilbert-Huang transform application for the recognition of seismic precursory phenomena by the analysis of VLF transmission signals of the European Network.  

NASA Astrophysics Data System (ADS)

In this paper the authors evaluate the suitability of the Hilber-Huang transformation (Empirical Mode Decomposition) in the recognition of seismic precursory phenomena from the analysis of signals which are transmitted by European station in the VLF frequency band. So, the results of the measurements and analysis of the received signals for the time periods of the earthquake occurrence in the area of Greece and the effectiveness of the method is being discussed.(in Greeks)

Skeberis, C.; Xenos, T. D.; Arabelos, D. N.; Spatalas, S.

2013-01-01

75

Identification of components in Zhi-Zi-Da-Huang decoction by HPLC coupled with electrospray ionization tandem mass spectrometry, photodiode array and fluorescence detectors  

Microsoft Academic Search

High-performance liquid chromatography (HPLC) coupled with electrospray ionization (ESI) tandem mass spectrometry (MS) in positive and negative ion mode and photodiode array (PDA) and fluorescence detectors (FD) was applied to simultaneously characterise thirty active components in Zhi-Zi-Da-Huang decoction (ZZDHD). The analysis was preformed on a Lichrospher C18 column (4.6mm×250mm, 5?m) using a binary eluent (0.1% aqueous acetic acid (A) and

Hang Wang; Fang Feng

2009-01-01

76

Evaluation of hepatoprotective effect of Zhi-Zi-Da-Huang decoction and its two fractions against acute alcohol-induced liver injury in rats  

Microsoft Academic Search

Aim of the studyTo investigate the hepatoprotective effect of Zhi-Zi-Da-Huang decoction (ZZDHD) and its two fractions (one is extracted with diethyl ether as a solvent from the water extract and is called ZD-DE for short, the other is the remained aqueous fraction after extracted with diethyl ether and is abbreviated as ZD-AQ) against acute alcohol-induced liver injury in rats.

Hang Wang; Fang Feng; Bo-Yang Zhuang; Ya Sun

2009-01-01

77

Gene expression patterns of hippocampus and cerebral cortex of senescence-accelerated mouse treated with Huang-Lian-Jie-Du decoction  

Microsoft Academic Search

Alzheimer's disease (AD) is a progressive, neurodegenerative disease, which primarily affects the elderly. Clinical signs of AD are characterized by the neuron loss and cognitive impairment. At gene and protein levels, the senescence-accelerated mouse\\/prone 8 (SAMP8) is a suitable animal model to investigate the fundamental mechanisms of age-related learning and memory deficits. Huang-Lian-Jie-Du decoction (HL), a well-known traditional Chinese medicinal

Yue Zheng; Xiao-Rui Cheng; Wen-Xia Zhou; Yong-Xiang Zhang

2008-01-01

78

Effects of a Chinese Herbal Medicine, Guan-Jen-Huang (Aeginetia indica Linn.), on Renal Cancer Cell Growth and Metastasis.  

PubMed

Aeginetia indica Linn. (Guan-Jen-Huang, GJH), a traditional Chinese herb, has the potential to be an immunomodulatory agent. The purpose of this study was to explore the effect of GJH in the treatment of renal cancer. Concentration-effect curves for the influence of GJH on cellular proliferation showed a biphasic shape. Besides, GJH had a synergistic effect on cytotoxicity when combined with 5-fluorouracil (5-FU)which may be due to the alternation of the chemotherapeutic agent resistance-related genes and due to the synergistic effects on apoptosis. In addition, treatment with GJH extract markedly reduced 786-O cell adherence to human umbilical vein endothelial cells (HUVECs) and decreased 786-O cell migration and invasion. In a xenograft animal model, GJH extract had an inhibitory effect on tumor cell-induced metastasis. Moreover, western blot analysis showed that the expression of intercellular adhesion molecule-1 (ICAM-1) in 786-O cells was significantly decreased by treatment with GJH extract through inactivation of nuclear factor-?B (NF-?B). These results suggest that GJH extract has a synergistic effect on apoptosis induced by chemotherapeutic agents and an inhibitory effect on cell adhesion, migration, and invasion, providing evidence for the use of water-based extracts of GJH as novel alternative therapeutic agents in the treatment of human renal cancer. PMID:22028734

Liu, Yu-Huei; Li, Meng-Luen; Hsu, Meng-Yu; Pang, Ya-Yueh; Chen, I-Ling; Chen, Ching-Kuei; Tang, Sai-Wen; Lin, Hsuan-Yuan; Lin, Jung-Yaw

2011-10-18

79

Nonlinear phase interaction between nonstationary signals: A comparison study of methods based on Hilbert-Huang and Fourier transforms  

PubMed Central

Phase interactions among signals of physical and physiological systems can provide useful information about the underlying control mechanisms of the systems. Physical and biological recordings are often noisy and exhibit nonstationarities that can affect the estimation of phase interactions. We systematically studied effects of nonstationarities on two phase analyses including (i) the widely used transfer function analysis (TFA) that is based on Fourier decomposition and (ii) the recently proposed multimodal pressure flow (MMPF) analysis that is based on Hilbert-Huang transform (HHT) —an advanced nonlinear decomposition algorithm. We considered three types of nonstationarities that are often presented in physical and physiological signals: (i) missing segments of data, (ii) linear and step-function trends embedded in data, and (iii) multiple chaotic oscillatory components at different frequencies in data. By generating two coupled oscillatory signals with an assigned phase shift, we quantify the change in the estimated phase shift after imposing artificial nonstationarities into the oscillatory signals. We found that all three types of nonstationarities affect the performances of the Fourier-based and the HHT-based phase analyses, introducing bias and random errors in the estimation of the phase shift between two oscillatory signals. We also provided examples of nonstationarities in real physiological data (cerebral blood flow and blood pressure) and showed how nonstationarities can complicate result interpretation. Furthermore, we propose certain strategies that can be implemented in the TFA and the MMPF methods to reduce the effects of nonstationarities, thus improving the performances of the two methods.

Novak, Vera; Peng, C.-K.; Liu, Yanhui

2009-01-01

80

An approach based on wavelet packet decomposition and Hilbert-Huang transform (WPD-HHT) for spindle bearings condition monitoring  

NASA Astrophysics Data System (ADS)

In order to prevent possible damages to the spindle systems, reliable monitoring techniques are required to provide valuable information on the condition of the spindle condition. A technique is proposed for monitoring spindle bearings conditions via the use of acoustic emission (AE) signals, which implements Hilbert-Huang transform (HHT) analysis to extract the crucial characteristic from the measured data to correlate spindle running condition. The HHT becomes a promising technique in extracting the properties of nonlinear and non-stationary signal. However, the original HHT has several deficiencies, which eventually lead to misinterpretation to the final results. The improved version of HHT is proposed and used to overcome the weakness of the original HHT. The simulation and experimental results are used to verify the effectiveness of the WPD-HHT and therefore Hilbert marginal spectral, compared to traditional Fourier transform. Experimental results are presented to examine and explore the effectiveness of AE for monitoring spindle bearings conditions. It is concluded that good correlation existed between the results obtained by AE data and the increase in the preload, and change in the dimensions and geometry of the spindle bearings and their housings as the temperature increases. In support of this finding, vibration and acceleration data are also used to assess the amount changes in the antistrophic stiffness and radial error motion.

Law, Leh-Sung; Kim, Jong Hyun; Liew, Willey Y. H.; Lee, Sun-Kyu

2012-11-01

81

A Comparative study of VLF and LF disturbunces prior earthquake events by the use of Hilbert-Huang Transformation  

NASA Astrophysics Data System (ADS)

It is well known that the lower ionospheric layer acts as a waveguide for the VLF and LF radiowaves.In the frame of the International Network for Frontier Research on Earthquake Precursors(INFREP)an Elettronica radio receiver was set in operation in Thessaloniki-Greece, in order to collect the VLF-LF signals transmitted by ten stations across Europe. The sampling rate was one-minute. The collected signal samples were analysed using the Hilbert-Huang transformation (HHT). More specifically the VLF and LF variations during three earthquakes were analysed; (1) the earthquake at Peshkopia-Albania (6 September 2009, Long. 41.62, Lat. 20.41, 5.4 R, 10 km depth) at a distance of 242.45 km from Thessaloniki; (2)the earthquakes at Libolesh-Albania (12 September 2009, Lat. 41.49, Long 20.44, 4.2 R, depth 13 ?m) 228 km away from Thessaloniki and (3) the Durres-Albania (15 September 2009, Lat. 41.42, Long 19.16, 4.0 Richter, depth 33 km) 329 km away from Thessaloniki. The results of our analysis indicate that: a) The VLF signal variations seem to be stronger compared to the LF ones when the earthquakes are stronger, whereas the opposite seems to hold for weaker earthquakes.b) The HHT analysis used to de-noise the signals indicated that the first 4 or 5 IMFs represent noise in these three case studies. In concluding we may say that it is possible to distinguish ionospheric precursor phenoma from natural noise using HHT analysis.

Anastasiadis, H.; Xenos, Th. D.; Contadakis, M. E.; Arabelos, D. N.; Migga, E.

2010-05-01

82

An in vitro study of the antioxidant activities and effect on human DNA of the Chinese herbal decoction 'Liu Wei Di Huang'.  

PubMed

A Chinese medicinal formulation, 'Liu Wei Di Huang', and its individual components have been tested for the genoprotective effect on human DNA by the comet assay. Results showed no DNA protection contributed by this prescription. However, the aqueous extracts of individual herbs, namely Cortex Moutan and Rhizoma Dioscoreae, were able to decrease by 10-15% the DNA stand break from hydrogen peroxide-mediated oxidative stress. This provides insight to further evaluate the interaction among herbs and the search for the active ingredient responsible for the DNA protective effect. PMID:19919513

Szeto, Yim-Tong; Lei, Pui-Cheong; Ngai, Kam-Leong; Yiu, Andy Tak-Wah; Chan, Catarina Sin-Pek; Kok, Edith Wun-Fong; Leong, Chi-Wa

2009-12-01

83

Spatial correlation between malaria cases and water-bodies in Anopheles sinensis dominated areas of Huang-Huai plain, China  

PubMed Central

Background Malaria re-emerged in the Huang-Huai Plain of central China during 2006–2008, dominated with Anopheles sinensis as a vector. However, there is no information on strategies based on multi-factor analysis to effectively control the re-emergence of malaria in these areas. Previous experience indicates some relationship between the distribution of water bodies and malaria cases, but more detailed data are not available and in-depth studies have not been conducted up to now. The objective of this study was to identify the relationship between the distribution of water bodies and presentation of malaria cases using spatial analysis tools in order to provide guidance to help formulate effective strategies for use in controlling the sources of malaria infection, based on the identification of risk areas and population. Methods The geographic information of malaria cases and their surrounding water bodies were collected from Suixi, Guoyang, Guzhen, Yingshang, Fengyang and Yongqiao County in Anhui province, Yongcheng and Tongbai County in Henan province. All malaria cases distributed in 113 villages in these 8 counties were collected from the China Information System for Disease Control and Prevention and confirmed by household investigation. Data on GIS and malaria cases were mapped and analyzed with the software of ArcGIS 9.2 to identify the spatial correlation between malaria cases and water bodies. The distance from households with malaria cases to the nearest water bodies was used to calculate the OR value by Chi-square test. The risk area was identified through the comparison of OR values in different distances. Results 357 malaria cases and their GPS data as well as surrounding water bodies were collected and analyzed. 74% of malaria cases were located within the extent of 60?m proximity to the water bodies. The risk rate of people living there and presenting with malaria was significantly higher than others (OR?=?1.6,95%CI (1.042, 2.463),P?

2012-01-01

84

Bogoliubov theory and Lee-Huang-Yang corrections in spin-1 and spin-2 Bose-Einstein condensates in the presence of the quadratic Zeeman effect  

NASA Astrophysics Data System (ADS)

We develop Bogoliubov theory of spin-1 and spin-2 Bose-Einstein condensates (BECs) in the presence of a quadratic Zeeman effect, and derive the Lee-Huang-Yang (LHY) corrections to the ground-state energy, pressure, sound velocity, and quantum depletion. We investigate all the phases of spin-1 and spin-2 BECs that can be realized experimentally. We also examine the stability of each phase against quantum fluctuations and the quadratic Zeeman effect. Furthermore, we discuss a relationship between the number of symmetry generators that are spontaneously broken and that of Nambu-Goldstone (NG) modes. It is found that in the spin-2 nematic phase there are special Bogoliubov modes that have gapless linear dispersion relations but do not belong to the NG modes.

Uchino, Shun; Kobayashi, Michikazu; Ueda, Masahito

2010-06-01

85

Quality evaluation of commercial Huang-Lian-Jie-Du-Tang based on simultaneous determination of fourteen major chemical constituents using high performance liquid chromatography.  

PubMed

Huang-Lian-Jie-Du-Tang (HLJDT), comprising Coptidis Rhizoma, Scutellariae Radix, Phellodendri Cortex and Gardeniae Fructus, is one of the commonly used Chinese medicine formulas for clearing heat and detoxifying. Quality control of the herbal complex like Chinese medicine formulas still remains a challenge. The successful approval of botanical drug Veregen by FDA indicated the importance of quantitative analysis in quality control of herbal medicines. In this study, an effective quantitative method based on conventional HPLC-DAD was developed for simultaneous determination of fourteen major ingredients (seven alkaloids, four flavonoids, three terpenes) in HLJDT. The established method was well validated in terms of linearity, sensitivity, precision, accuracy and stability and then successfully applied to quality evaluation of commercial HLJDT samples. The developed method can quantitatively determine up to 70% of the chemicals of commercial HLJDT sample and effectively revealed the significant variation in the quality of the commercial HLJDT samples collected from different locations. PMID:23973454

Kwok, Ka-Yan; Xu, Jun; Ho, Hing-Man; Chen, Hu-Biao; Li, Min; Lang, Yan; Han, Quan-Bin

2013-08-05

86

Huang-lian-jie-du-tang protects rats from cardiac damages induced by metabolic disorder by improving inflammation-mediated insulin resistance.  

PubMed

Huang-lian-jie-du-tang (HLJDT), a traditional Chinese medicine, has been shown to improve insulin resistance (IR) induced by inflammation, a key event in the development of metabolic syndrome (MS). The present study aimed to investigate the protective effects of HLJDT on MS and explore the underlying mechanism. MS rats were established with obese-diets and treated with normal saline, aspirin or HLJDT. The myocardial lesions were identified by echocardiogram, transmission electron microscope, and Sirius-red staining. The inflammatory cytokines were measured by ELISA and real-time PCR. The activation of NF-?B, JNK, SOCS3, IRS1 and AKT in the heart was detected by immunohistochemistry and Western blot analysis. Compared with the controls, MS rats developed obvious obesity, hypertension, dyslipidemia, IR, inflammation, and cardiac damage. Moreover, phosphorylated IRS-1 at Ser307 was correlated with the activation of NF-?B, JNK and SOCS3 and the inhibition of AKT in the heart from MS rats. These data suggest that serine phosphorylation of IRS-1 in response to inflammation is mediated, in part, by NF-?B, JNK and SOCS3. Notably, HLJDT inhibited the activation of NF-?B and reduced serine phosphorylation of IRS-1. In summary, HLJDT protects myocardium from IR-mediated injury by inhibiting serine phosphorylation of IRS-1 in MS rats. PMID:23840732

Li, Chuan Bao; Li, Xiao Xing; Chen, Yu Guo; Gao, Hai Qing; Bu, Pei Li; Zhang, Yun; Ji, Xiao Ping

2013-06-28

87

Possible effect of solar activity on variation of the tree-rings of a 500 a platycladus orientalis at the Mausoleum of Emperor Huang  

NASA Astrophysics Data System (ADS)

The variation of the tree-ring’s index of a platycladus orientalis at the Mausoleum of Emperor Huang and of a long series of sunspots relative number during AD1470-1974 are analyzed by using the wavelet power spectrum method, and their variation characters are also discussed. It is determined that the tree-ring’s variation has cycles of approximate 2-7, 11, 93 and 150 a. Two data series are used for analyzing sunspot relative number (SSN) variation. First, the analysis of the annual average SSN during AD1700-1974 proved that variation cycles are about 11, 50, and 93 a; then, the data during AD1465-1975 obtained from the decadal average SSN train over 7000 a reconstructed on the geomagnetic data is analyzed and its variation cycles are about 50, 90, and 160 a. Besides the tree-rings cycle of 2-7 a is commonly considered to be related to ENSO, while 11 a cycle is related to solar Schwabe cycle; in addition, it is possible that the cycles of 90 and150 a are likely to be related to solar Gleissberg cycle and Suess cycle. The correlations between them are possibly due to the effect of solar activity on the climate and additionally on the tree’s growth.

Feng, Bo; Han, Yanben

2009-04-01

88

Validation of crop model for simulating summer maize in the Huang-Huai Plain of China and its application on analyzing drought effects  

NASA Astrophysics Data System (ADS)

Using datasets of 1991-2004 meteorological and soil data as well as field management from 8 stations in the summer-sown maize zone over the Huang-Huai River Basin, North China, study is performed of the water deficit in various phases of growth of the crop impacting on the final yield by means of CERES-Maize of DSSAT Version 4.0, whose parameters are adjusted for local conditions. Results show that 1) in the jointing stage of vegetative growth and the filling stage (especially its earlier part) of the reproduction growth, field moisture acts as a key factor affecting the yield; 2) deficient moisture in the 7-leaf and jointing periods would cause maximum leaf area index to significantly drop, keeping dry matter from accumulation, leading to appreciable diminution of weight of dry stem and leaves; 3) water deficit in the earlier (middle) filling stage would result in reduced number of grains per cob (decrease substantially the weight of 100 grains). The findings in conjunction with measured moisture can be used to implement the "efficient irrigation with less water" practice in this vast region.

Li, Shuyan; Liu, Ronghua; Cheng, Lin; Fang, Wensong; Wang, Xinli

2009-08-01

89

Hilbert-Huang Transform: A Spectral Analysis Tool Applied to Sunspot Number and Total Solar Irradiance Variations, as well as Near-Surface Atmospheric Variables  

NASA Astrophysics Data System (ADS)

Hilbert-Huang transform (HHT) is a relatively new data analysis tool which is used to analyze nonstationary and nonlinear time series data. It consists of an algorithm, called empirical mode decomposition (EMD), which extracts the cyclic components embedded within time series data, as well as Hilbert spectral analysis (HSA) which displays the time and frequency dependent energy contributions from each component in the form of a spectrogram. The method can be considered a generalized form of Fourier analysis which can describe the intrinsic cycles of data with basis functions whose amplitudes and phases may vary with time. The HHT will be introduced and compared to current spectral analysis tools such as Fourier analysis, short-time Fourier analysis, wavelet analysis and Wigner-Ville distributions. A number of applications are also presented which demonstrate the strengths and limitations of the tool, including analyzing sunspot number variability and total solar irradiance proxies as well as global averaged temperature and carbon dioxide concentration. Also, near-surface atmospheric quantities such as temperature and wind velocity are analyzed to demonstrate the nonstationarity of the atmosphere.

Barnhart, B. L.; Eichinger, W. E.; Prueger, J. H.

2010-12-01

90

Metabolism and pharmacokinetics of san-huang-xie-xin-tang, a polyphenol-rich chinese medicine formula, in rats and ex-vivo antioxidant activity.  

PubMed

San-Huang-Xie-Xin-Tang (SHXXT), a widely used Chinese herbal formula, consists of rhizomes of Rheum officinale, roots of Scutellaria baicalensis and rhizomes of Coptis chinesis. This study investigated the metabolism and pharmacokinetics of polyphenols in SHXXT, including baicalin, baicalein, wogonin, emodin, aloe-emodin, rhein and chrysophanol. The quantitation methods of SHXXT decoction and rat serum using high performance liquid chromatography were developed and validated in this study. After oral administration of SHXXT decoction to rats, the parent forms of various constituents and their conjugated metabolites in serum were determined before and after hydrolysis with ?-glucuronidase and sulfatase. The results showed that only free form of rhein can be quantitated, whereas the parent forms of coptisine, palmatine, berberine, baicalein, wogonin, emodin, aloe-emodin and chrysophanol were not detected in serum. The glucuronides of baicalein, wogonin, emodin, aloe-emodin, rhein and chrysophanol were the predominant forms in bloodstream. In order to evaluate the in vivo antioxidant activity of SHXXT, the serum metabolite of SHXXT was prepared, characterized and followed by evaluation of the effect on AAPH-induced hemolysis. The results indicated that metabolites of SHXXT exhibited significant free radical scavenging activity. We suggest that biologists redirect their focus to the bioactivity of the conjugated metabolites of these polyphenols. PMID:19737807

Shia, Chi-Sheng; Hou, Yu-Chi; Juang, Shin-Hun; Tsai, Shang-Yuan; Hsieh, Pei-Hsun; Ho, Lu-Ching; Chao, Pei-Dawn Lee

2011-06-07

91

Metabolism and Pharmacokinetics of San-Huang-Xie-Xin-Tang, a Polyphenol-Rich Chinese Medicine Formula, in Rats and Ex-Vivo Antioxidant Activity  

PubMed Central

San-Huang-Xie-Xin-Tang (SHXXT), a widely used Chinese herbal formula, consists of rhizomes of Rheum officinale, roots of Scutellaria baicalensis and rhizomes of Coptis chinesis. This study investigated the metabolism and pharmacokinetics of polyphenols in SHXXT, including baicalin, baicalein, wogonin, emodin, aloe-emodin, rhein and chrysophanol. The quantitation methods of SHXXT decoction and rat serum using high performance liquid chromatography were developed and validated in this study. After oral administration of SHXXT decoction to rats, the parent forms of various constituents and their conjugated metabolites in serum were determined before and after hydrolysis with ?-glucuronidase and sulfatase. The results showed that only free form of rhein can be quantitated, whereas the parent forms of coptisine, palmatine, berberine, baicalein, wogonin, emodin, aloe-emodin and chrysophanol were not detected in serum. The glucuronides of baicalein, wogonin, emodin, aloe-emodin, rhein and chrysophanol were the predominant forms in bloodstream. In order to evaluate the in vivo antioxidant activity of SHXXT, the serum metabolite of SHXXT was prepared, characterized and followed by evaluation of the effect on AAPH-induced hemolysis. The results indicated that metabolites of SHXXT exhibited significant free radical scavenging activity. We suggest that biologists redirect their focus to the bioactivity of the conjugated metabolites of these polyphenols.

Shia, Chi-Sheng; Hou, Yu-Chi; Juang, Shin-Hun; Tsai, Shang-Yuan; Hsieh, Pei-Hsun; Ho, Lu-Ching; Chao, Pei-Dawn Lee

2011-01-01

92

Neuroprotective Effects of San-Huang-Xie-Xin-Tang in the MPP+/MPTP Models of Parkinson's Disease In Vitro and In Vivo  

PubMed Central

San-Huang-Xie-Xin-Tang (SHXT), composed of Coptidis rhizoma, Scutellariae radix, and Rhei rhizoma, is a traditional Chinese medicine used for complementary and alternative therapy of cardiovascular and neurodegenerative diseases via its anti-inflammatory and antioxidative effects. The aim of this study is to investigate the protective effects of SHXT in the 1–methyl–4–phenylpyridinium (MPP+)/1–methyl–4–phenyl–1,2,3,6–tetrahydropyridine (MPTP) models of Parkinson's disease. Rat primary mesencephalic neurons and mouse Parkinson disease model were used in this study. Oxidative stress was induced by MPP+ in vitro and MPTP in vivo. In MPP+-treated mesencephalic neuron cultures, SHXT significantly increased the numbers of TH-positive neurons. SHXT reduced apoptotic signals (cytochrome and caspase) and apoptotic death. MPP+-induced gp91phox activation and ROS production were attenuated by SHXT. In addition, SHXT increased the levels of GSH and SOD in MPP+-treated neurons. In MPTP animal model, SHXT markedly increased TH-positive neurons in the substantia nigra pars compacta (SNpc) and improved motor activity of mice. In conclusion, the present results reveal the evidence that SHXT possesses beneficial protection against MPTP-induced neurotoxicity in this model of Parkinson's disease via its antioxidative and antiapoptotic effects. SHXT might be a potentially alternative and complementary medicine for neuroprotection.

Lo, Yi-Ching; Shih, Yu-Tzu; Tseng, Yu-Ting; Hsu, Hung-Te

2012-01-01

93

Preparation and in vitro aerosol performance of spray-dried Shuang-Huang-Lian corrugated particles in carrier-based dry powder inhalers.  

PubMed

The development of dry powder inhalation (DPI) products of traditional Chinese medicine (TCM) remains to be a challenge due to chemical complexity and batch-to-batch variations in constituent composition. This study was to investigate the feasibility of using spray-dried corrugated particles to improve the aerodynamic performance of a TCM, Shuang-Huang-Lian (SHL), in carrier-based DPI. Particles with different surface roughness were spray-dried by the addition of leucine and concomitant manipulation of spray-drying parameters. The surface roughness was determined by atomic force microscopy, whilst the aerodynamic performance of drug particle-mannitol/lactose blends was evaluated using a next-generation pharmaceutical impactor through a Cyclohaler. Although the emission efficiency for corrugated particle-based DPI was ~10% lower than that for smooth SHL, the fine particle fractions (FPF(<4.4 ?m)) of 32.4-36.8% for the former were significantly higher than those of 14.7-16.2% for the latter. In particular, the FPF and fraction of drug detached from the carrier appeared not to be significantly affected by the variation in constituent composition of SHL. This study demonstrates that the use of corrugated particles in carrier-based DPI improved aerosol performance by facilitating drug detachment from the carrier, independent of variation in constituent composition, and such particles were potentially applicable to the development of SHL DPI products. PMID:22644707

Yang, Jing-Jing; Liu, Chun-Yu; Quan, Li-Hui; Liao, Yong-Hong

2012-05-30

94

Functional Representation for the Born-Oppenheimer Diagonal Correction and Born-Huang Adiabatic Potential Energy Surfaces for Isotopomers of H3  

SciTech Connect

Multireference configuration interaction (MRCI) calculations of the Born-Oppenheimer diagonal correction (BODC) for H3 were performed at 1397 symmetry-unique configurations using the Born-Handy approach; isotopic substitution leads to 4041 symmetry-unique configurations for the DH2 mass combination. These results were then fit to a functional form that permits calculation of the BODC for any combination of isotopes. Mean unsigned fitting errors on a test grid of configurations not included in the fitting process were 0.14, 0.12, and 0.65 cm?1 for the H3, DH2, and MuH2 isotopomers, respectively. This representation can be combined with any Born-Oppenheimer potential energy surface (PES) to yield Born-Huang (BH) PESs; herein we choose the CCI potential energy surface, the uncertainties of which (~0.01 kcal/mol) are much smaller than the magnitude of the BODC. FORTRAN routines to evaluate these BH surfaces are provided. Variational transition state theory calculations are presented comparing thermal rate constants for reactions on the BO and BH surfaces to provide an initial estimate of the significance of the diagonal correction for the dynamics.

Mielke, Steven L.; Schwenke, David; Schatz, George C.; Garrett, Bruce C.; Peterson, Kirk A.

2009-04-23

95

Functional representation for the born-oppenheimer diagonal correction and born-huang adiabatic potential energy surfaces for isotopomers of H3.  

PubMed

Multireference configuration interaction (MRCI) calculations of the Born-Oppenheimer diagonal correction (BODC) for H(3) were performed at 1397 symmetry-unique configurations using the Handy-Yamaguchi-Schaefer approach; isotopic substitution leads to 4041 symmetry-unique configurations for the DH(2) mass combination. These results were then fit to a functional form that permits calculation of the BODC for any combination of isotopes. Mean unsigned fitting errors on a test grid of configurations not included in the fitting process were 0.14, 0.12, and 0.65 cm(-1) for the H(3), DH(2), and MuH(2) isotopomers, respectively. This representation can be combined with any Born-Oppenheimer potential energy surface (PES) to yield Born-Huang (BH) PESs; herein, we choose the CCI potential energy surface, the uncertainties of which ( approximately 0.01 kcal/mol) are much smaller than the magnitude of the BODC. Fortran routines to evaluate these BH surfaces are provided. Variational transition state theory calculations are presented comparing thermal rate constants for reactions on the BO and BH surfaces to provide an initial estimate of the significance of the diagonal correction for the dynamics. PMID:19290604

Mielke, Steven L; Schwenke, David W; Schatz, George C; Garrett, Bruce C; Peterson, Kirk A

2009-04-23

96

A traditional Chinese medicine JiuHuangLian (Rhizoma coptidis steamed with rice wine) reduces oxidative stress injury in type 2 diabetic rats.  

PubMed

Oxidative stress and oxidative stress mediated ?-cell injury are the initial factors of diabetes pathogenesis. Traditional Chinese medicine believes that JiuHuangLian (JHL, Rhizoma Coptidis steamed with rice wine) is an effective agent on diabetes treatment. In present study, we evaluated the antioxidant and lightening ?-cell injury of JHL in streptozotocin and a high-glucose/high-fat diet-induced diabetic rats. After 30 days treatment with JHL, glucose tolerance and insulin tolerance of diabetic rats were improved significantly. JHL also could decrease fasting blood glucose and glycosylated hemoglobin levels, increase insulin level and insulin sensitivity index. Moreover, lipid metabolism disorder also adjusted, which manifested as decreased total cholesterol, total glyceride and free fatty acid levels. Meanwhile, a significant increase in superoxide dismutase activity and glutathione content were observed in JHL treated rats, oxidative stress markers such as reactive oxygen species, malondialdehyde and nitric oxide also were decreased by JHL treatment. Furthermore, low expression of caspase-3 were shown in pancreatic immunohistochemistry of JHL treated rats, which exhibited anti-apoptosis effect of ?-cell. The histological evidence suggests that JHL effectively rescues the islet atrophied from oxidative stress-mediated ?-cell damage. These findings demonstrate the ?-cell functional protective nature of JHL by attenuating oxidative stress and inhibiting ?-cell damage. PMID:23791751

Li, Jia-chuan; Shen, Xiao-fei; Meng, Xian-li

2013-06-18

97

Comparative Pharmacokinetic Study of Chlorogenic Acid after Oral Administration of Lonicerae Japonicae Flos and Shuang-Huang-Lian in Normal and Febrile Rats.  

PubMed

Shuang-Huang-Lian (SHL), a famous traditional Chinese medicine recipe containing Lonicerae Japonicae Flos (LJF), Forsythiae Fructus, and Scutellariae Radix, is clinically used for the treatment of fever and acute upper respiratory tract infection. In this research, a comparative study was conducted to compare the pharmacokinetic difference of chlorogenic acid (ChA) after oral administration of LJF and SHL to normal and febrile rats with approximately the same dose of 60?mg/kg, and the antipyrexia effect of LJF and SHL on rectal temperature changes induced by Baker's yeast was investigated. The results indicated that AUC0?-?t and plasma concentrations of ChA in the febrile rats were significantly higher than normal rats whether in the extract of LJF or SHL. In addition, SHL increased the values of AUC of ChA in both febrile and normal rats compared with LJF alone (p?

Gao, Ru; Lin, Yining; Liang, Ge; Yu, Boyang; Gao, Yuan

2013-02-28

98

Toxicology Evaluation of Realgar-Containing Niu-Huang-Jie-Du Pian as Compared to Arsenicals in Cell Cultures and in Mice  

PubMed Central

Niu-Huang-Jie-Du Pian (NHJD) is a widely used traditional Chinese medicine containing realgar (As4S4). Realgar has been included in many traditional medicines, but is often taken as arsenite for risk assessment. To evaluate true risk of realgar and realgar-containing NHJD, their toxicity was compared with common arsenicals. In cultured cells, the LC50 for NHJD (1200??M) and realgar (2000??M) was much higher than arsenite(35??M), arsenic trioxide (280??M), and arsenate (400??M). Acute toxicity in mice showed more severe liver and kidney injury after arsenite or arsenate, but was mild after realgar and NHJD, corresponding to cellular and tissue arsenic accumulation. The expressions of arsenic-sensitive stress gene metallothionein-1 were increased 3–7-folds after arsenite or arsenate, but were unaltered after NHJD and realgar. Thus, realgar and NHJD are much less toxic than arsenite and arsenate. The use of total arsenic to evaluate the safety of realgar and realgar-containing NHJD is inappropriate.

Miao, Jia-Wei; Liang, Shi-Xia; Wu, Qin; Liu, Jie; Sun, An-Sheng

2011-01-01

99

Atmospheric deposition as an important nitrogen load to a typical agroecosystem in the Huang-Huai-Hai Plain. 1. Measurement and preliminary results  

NASA Astrophysics Data System (ADS)

Atmospheric nitrogen (N) deposition has been widely considered as an important N input into agroecosystems, but its measurement involves considerable uncertainties with various methods. In this study, a field sampler with distilled water as a surrogate surface was developed and trialed for the collection of dry and wet N deposition. The direct measuring results were compared with the value calculated by the N mass balance method (crop N uptake from plots receiving no N fertilizers of the long-term fertilization experiment in the monitoring station). The results indicated that exposure durations of 3-5 days and water volumes of 2000-2800 ml were tested to be suitable to collect dry N deposition, while water volumes of less than 1000 ml and sampling conducted immediately after rain event were found to be appropriate for wet N collection under the present experimental conditions. The monitoring work was conducted from June 2008 to May 2009, and annual N deposition totaled up to 40.32 kg N ha -1, of which dry deposition accounted for 62.45%. NH 4-N was the dominant species in N deposition and contributed 62.68% and 66.00% to wet and dry deposition, respectively. Organic N (O-N) was found to make greater contributions than NO 3-N in both dry and wet depositions. Total N deposition was parallel to the results estimated by the method of mass N balance from the long-term experiment, as 45.6 kg N ha -1. These results provide helpful knowledge to elucidate the N deposition scenario of a typical agroecosystem and can be of great importance for the calculation of fertilizer recommendations in the Huang-Huai-Hai Plain.

Huang, Ping; Zhang, Jiabao; Zhu, Anning; Xin, Xiuli; Zhang, Congzhi; Ma, Donghao

2011-07-01

100

TIME-FREQUENCY ANALYSIS OF THE SUPERORBITAL MODULATION OF THE X-RAY BINARY SMC X-1 USING THE HILBERT-HUANG TRANSFORM  

SciTech Connect

The high-mass X-ray binary SMC X-1 exhibits a superorbital modulation with a dramatically varying period ranging between {approx}40 days and {approx}60 days. This research studies the time-frequency properties of the superorbital modulation of SMC X-1 based on the observations made by the All-Sky Monitor (ASM) onboard the Rossi X-ray Timing Explorer (RXTE). We analyzed the entire ASM database collected since 1996. The Hilbert-Huang transform (HHT), developed for non-stationary and nonlinear time-series analysis, was adopted to derive the instantaneous superorbital frequency. The resultant Hilbert spectrum is consistent with the dynamic power spectrum as it shows more detailed information in both the time and frequency domains. The RXTE observations show that the superorbital modulation period was mostly between {approx}50 days and {approx}65 days, whereas it changed to {approx}45 days around MJD 50,800 and MJD 54,000. Our analysis further indicates that the instantaneous frequency changed to a timescale of hundreds of days between {approx}MJD 51,500 and {approx}MJD 53,500. Based on the instantaneous phase defined by HHT, we folded the ASM light curve to derive a superorbital profile, from which an asymmetric feature and a low state with barely any X-ray emissions (lasting for {approx}0.3 cycles) were observed. We also calculated the correlation between the mean period and the amplitude of the superorbital modulation. The result is similar to the recently discovered relationship between the superorbital cycle length and the mean X-ray flux for Her X-1.

Hu, Chin-Ping; Chou, Yi; Yang, Ting-Chang; Su, Yi-Hao [Graduate Institute of Astronomy, National Central University, Jhongli 32001, Taiwan (China); Wu, Ming-Chya, E-mail: m929011@astro.ncu.edu.tw, E-mail: yichou@astro.ncu.edu.tw [Research Center for Adaptive Data Analysis, National Central University, Jhongli 32001, Taiwan (China)

2011-10-20

101

San-Huang-Xie-Xin-Tang Protects against Activated Microglia- and 6-OHDA-Induced Toxicity in Neuronal SH-SY5Y Cells  

PubMed Central

San-Huang-Xie-Xin-Tang (SHXT), composed of Coptidis rhizoma, Scutellariae radix and Rhei rhizoma, is a traditional Chinese herbal medicine used to treat gastritis, gastric bleeding and peptic ulcers. This study investigated the neuroprotective effects of SHXT on microglia-mediated neurotoxicity using co-cultured lipopolysaccharide (LPS)-activated microglia-like BV-2 cells with neuroblastoma SH-SY5Y cells. Effects of SHXT on 6-hydroxydopamine (6-OHDA)-induced neurotoxicity were also examined in SH-SY5Y cells. Results indicated SHXT inhibited LPS-induced inflammation of BV-2 cells by downregulation of iNOS, NO, COX-2, PGE2, gp91phox, iROS, TNF-?, IL-1?, inhibition of I?B? degradation and upregulation of HO-1. In addition, SHXT increased cell viability and down regulated nNOS, COX-2 and gp91phox of SH-SY5Y cells co-cultured with LPS activated BV-2 cells. SHXT treatment increased cell viability and mitochondria membrane potential (MMP), decreased expression of nNOS, COX-2, gp91phox and iROS, and inhibited I?B? degradation in 6-OHDA-treated SH-SY5Y cells. SHXT also attenuated LPS activated BV-2 cells- and 6-OHDA-induced cell death in differentiated SH-SY5Y cells with db-cAMP. Furthermore, SHXT-inhibited nuclear translocation of p65 subunit of NF-?B in LPS treated BV-2 cells and 6-OHDA treated SH-SY5Y cells. In conclusion, SHXT showed protection from activated microglia- and 6-OHDA-induced neurotoxicity by attenuating inflammation and oxidative stress.

Shih, Yu-Tzu; Chen, Ing-Jun; Wu, Yang-Chang; Lo, Yi-Ching

2011-01-01

102

Time-frequency Analysis of the Superorbital Modulation of the X-Ray Binary SMC X-1 Using the Hilbert-Huang Transform  

NASA Astrophysics Data System (ADS)

The high-mass X-ray binary SMC X-1 exhibits a superorbital modulation with a dramatically varying period ranging between ~40 days and ~60 days. This research studies the time-frequency properties of the superorbital modulation of SMC X-1 based on the observations made by the All-Sky Monitor (ASM) onboard the Rossi X-ray Timing Explorer (RXTE). We analyzed the entire ASM database collected since 1996. The Hilbert-Huang transform (HHT), developed for non-stationary and nonlinear time-series analysis, was adopted to derive the instantaneous superorbital frequency. The resultant Hilbert spectrum is consistent with the dynamic power spectrum as it shows more detailed information in both the time and frequency domains. The RXTE observations show that the superorbital modulation period was mostly between ~50 days and ~65 days, whereas it changed to ~45 days around MJD 50,800 and MJD 54,000. Our analysis further indicates that the instantaneous frequency changed to a timescale of hundreds of days between ~MJD 51,500 and ~MJD 53,500. Based on the instantaneous phase defined by HHT, we folded the ASM light curve to derive a superorbital profile, from which an asymmetric feature and a low state with barely any X-ray emissions (lasting for ~0.3 cycles) were observed. We also calculated the correlation between the mean period and the amplitude of the superorbital modulation. The result is similar to the recently discovered relationship between the superorbital cycle length and the mean X-ray flux for Her X-1.

Hu, Chin-Ping; Chou, Yi; Wu, Ming-Chya; Yang, Ting-Chang; Su, Yi-Hao

2011-10-01

103

San-Huang-Xie-Xin-Tang Prevents Rat Hearts from Ischemia/Reperfusion-Induced Apoptosis through eNOS and MAPK Pathways  

PubMed Central

San-Huang-Xie-Xin-Tang (SHXT) is a traditional Chinese medication consisting of three herbs, namely Coptidis rhizome, Scutellariae radix and Rhei rhizome. This study aimed to examine the cardioprotective effects of SHXT in a rat model of acute myocardial apoptosis induced by ischemia/reperfusion (I/R). Vehicle (intravenous saline) or SHXT (intravenous or oral) was administered prior to I/R (occlusion of left coronary artery for 45?min followed by reperfusion for 2?h). In the vehicle group, myocardial I/R caused myocardial infarction with increased plasma cardiac enzymes, severe arrhythmia and mortality. Myocardial apoptosis was induced by I/R as evidenced by DNA ladder and Bcl-2/Bax ratio. In the SHXT group, we found that SHXT significantly reduced plasma levels of cardiac enzymes, arrhythmia scores (from 5 ± 1 to 2 ± 1, P < .01) and mortality rate (from 53 to 0%, P < .01). In addition, pretreatment with intravenous SHXT reduced the infarct size dose-dependently when compared with the vehicle group (10?mg?kg?1: 14.0 ± 0.2 versus 44.5 ± 5.0%, and 30?mg?kg?1: 6.2 ± 1.2% versus 44.5 ± 5.0%, both P < .01). Similarly, oral administration of SHXT reduced the infarct size dose-dependently. Furthermore, SHXT markedly decreased the apoptosis induced by I/R with increased Bcl-2/Bax ratio. Finally, we found that SHXT counteracted the I/R-induced downstream signaling, resulting in increased myocardial eNOS expression and plasma nitrite, and decreased activation of ERK1/2, p38 and JNK. These data suggest that SHXT has cardioprotective effects against I/R-induced apoptosis, and that these effects are mediated, at least in part, by eNOS and MAPK pathways.

Liou, Shu-Fen; Ke, Hung-Jen; Hsu, Jong-Hau; Liang, Jyh-Chong; Lin, Hung-Hong; Chen, Ing-Jun; Yeh, Jwu-Lai

2011-01-01

104

Drought evolution characteristics and precipitation intensity changes during alternating dry-wet changes in the Huang-Huai-Hai River basin  

NASA Astrophysics Data System (ADS)

According to the Chinese climate divisions and the Huang-Huai-Hai River basin digital elevation map, the basin is divided into seven sub-regions by means of cluster analysis of the basin meteorological stations using the self-organizing map (SOM) neural network method. Based on the daily precipitation data of 171 stations for the years 1961-2011, the drought frequency changes with different magnitudes are analyzed and the number of consecutive days without precipitation is used to identify the drought magnitudes. The first precipitation intensity after a drought period is analyzed with the Pearson-III frequency curve, then the relationship between rainfall intensity and different drought magnitudes is observed, as are the drought frequency changes for different years. The results of the study indicated the following: (1) the occurrence frequency of different drought level shows an overall increasing trend; there is no clear interdecadal change shown, but the spatial difference is significant. The occurrence frequencies of severe and extraordinary drought are higher on the North China Plain, Hetao Plains in Ningxia-Inner Mongolia, as well as on the Inner Mongolia and the Loess Plateaus, and in the Fen-Wei Valley basin. (2) As the drought level increases, the probability of extraordinary rainstorm becomes lower, and the frequency of occurrence of spatial changes in different precipitation intensities vary. In the areas surrounding Bo Sea, the Shandong Peninsula and the Huai River downstream, as the drought level increases, the occurrence frequency of different precipitation intensities first shows a decreasing trend, which becomes an increasing trend when extraordinary drought occurs. In the middle and upper reaches of the Huai River basin, on the Hai River basin piedmont plain and Hetao Plains in Ningxia-Inner Mongolia, Inner Mongolia and Loess Plateaus, and in the Fen-Wei Valley basin, the probability of the different precipitation intensities shows an overall decreasing trend. The mountains with high attitude and Tibetan Plateau are located at high altitudes where the variation of different precipitation intensities with the increase in drought level is relatively complex. (3) As the drought frequency increases, areas I, II and V which are located on the coastal and in the river basin are vulnerable to extreme precipitation processes; areas III, IV, VI and VII are located in the inland area where heavier precipitation is not likely to occur.

Yan, D. H.; Wu, D.; Huang, R.; Wang, L. N.; Yang, G. Y.

2013-03-01

105

Gene expression patterns of hippocampus and cerebral cortex of senescence-accelerated mouse treated with Huang-Lian-Jie-Du decoction.  

PubMed

Alzheimer's disease (AD) is a progressive, neurodegenerative disease, which primarily affects the elderly. Clinical signs of AD are characterized by the neuron loss and cognitive impairment. At gene and protein levels, the senescence-accelerated mouse/prone 8 (SAMP8) is a suitable animal model to investigate the fundamental mechanisms of age-related learning and memory deficits. Huang-Lian-Jie-Du decoction (HL), a well-known traditional Chinese medicinal prescription, has been employed in the treatment of wide range of disease conditions. Modern pharmacological studies have showed that HL possesses many effects, which include amelioration of learning and memory function of CNS. This paper investigated the gene expression patterns of hippocampus and cerebral cortex of SAMP8, which were treated with HL employing the cDNA microarray and real time quantitative RT-PCR techniques. The results showed that HL has the significant modulating effects on age-related changes of the gene expressions in the hippocampus and cerebral cortex in SAMP8, which include genes that involved in signal transduction (Dusp12, Rps6ka1, Rab26, Penk1, Nope, Leng8, Syde1, Phb, Def8, Ihpk1, Tac2, Pik3c2a), protein metabolism (Ttc3, Amfr, Prr6, Ube2d2), cell growth and development (Ngrn, Anln, Dip3b, Acrbp), nucleic acid metabolism (Fhit, Itm2c, Cstf2t, Ddx3x, Ercc5, Pcgfr6), energy metabolism (Stub1, Uqcr, Nsf), immune response (C1qb), regulation of transcription (D1ertd161e, Gcn5l2, Ssu72), transporter (Slc17a7, mt-Co1), nervous system development (Trim3), neurogila cell differentiation (Tspan2) and 24 genes whose biological function and process were still unknown. It was suggested by the changes of the 62 genes with HL treatment that the ameliorating effect of HL on the cognitive impairments of SAMP8 might be achieved by multi-mechanism and multi-targets. PMID:18524483

Zheng, Yue; Cheng, Xiao-Rui; Zhou, Wen-Xia; Zhang, Yong-Xiang

2008-04-09

106

[Changes of China agricultural climate resources under the background of climate change. IV. Spatiotemporal change characteristics of agricultural climate resources in sub-humid warm-temperate irrigated wheat-maize agricultural area of Huang-Huai-Hai Plain].  

PubMed

Based on the 1961-2007 observation data from 66 meteorological stations in the sub-humid and warm-temperate irrigated wheat-maize agricultural area of Huang-Huai-Hai Plain, this paper analyzed the spatiotemporal change characteristics of agro-climate resources for chimonophilous and thermophilic crops in the area in 1961-1980 and 1981-2007. The analyzed items included the length of temperature-defined growth season and the active accumulative temperature, sunshine hours, precipitation, reference evapotranspiration, and aridity index during the temperature-defined growth season. With climate warming, the length of temperature-defined growth season of chimonophilous and thermophilic crops in the area in 1981-2007 extended by 7. 4 d and 6. 9 d, and the > or = 0 degrees C and > or = 10 degrees C accumulative temperature increased at a rate of 4.0-137.0 and 1.0-142.0 degrees C d (10 a)(-1), respectively, compared with those in 1961-1980. The sunshine hours during the temperature-defined growth season of the crops decreased markedly; and the precipitation during the temperature-defined growing season decreased in most parts of the area, being obvious in Hebei and north Shandong Province, but increased in north Anhui and southeast Henan Province. In most parts of the area, the reference evapotranspiration of chimonophilous and thermophilic crops during their temperature-defined growth season decreased, and the aridity index increased. PMID:21774311

Liu, Zhi-juan; Yang, Xiao-guang; Wang, Wen-feng

2011-04-01

107

Huang-Lian-Jie-Du-Tang supplemented with Schisandra chinensis Baill. and Polygonatum odoratum Druce improved glucose tolerance by potentiating insulinotropic actions in islets in 90% pancreatectomized diabetic rats.  

PubMed

We investigated to determine what effects, if any, the respective water extracts of Radix scutellariae (RS), Fructus schisandrae chinensis (FSC), Huang-Lian-Jie-Du-Tang (HLJDT), and HLJDT supplemented with FSC, and Rhizoma Polygonati odorati (HLJDT-M) would have on glucose tolerance by modulating glucose-stimulated insulin secretion, beta-cell mass, and morphometry in 90% pancreatectomized (Px) diabetic rats fed high-fat diets. Through the elevation of intracellular cAMP levels, FSC RS, HLJDT, and HLJDT-M increased insulin secretion in Min6 cells and GLP-1 secretion in NCI-H716 cells. After an 8-week period of treatment, it was found that HLJDT-M improved glucose tolerance in an oral glucose tolerance test in Px rats. HLJDT-M also potentiated first- and second-phase insulin secretion, but RS and HLJDT elevated only the second phase at hyperglycemic clamp. RS and HLJDT increased beta-cell mass by hyperplasia and hypertrophy, while HLJDT-M increased it only by hyperplasia. The rise in hyperplasia was associated with elevated IRS2 and PDX-1 expression in the islets. In conclusion, HLJDT-M worked as an anti-diabetic prescription by enhancing insulinotropic actions in diabetic rats. PMID:19897925

Park, Sunmin; Hong, Sang Mee; Ahn, Il Sung; Kim, Yang Jin; Lee, Jung Bok

2009-11-07

108

Characterization of large-scale fluctuations and short-term variability of Seine river daily streamflow (France) over the period 1950-2008 by empirical mode decomposition and the Hilbert-Huang transform  

NASA Astrophysics Data System (ADS)

Daily Seine river flow from 1950 to 2008 was analyzed using Hilbert-Huang Tranform (HHT). For the last ten years, this method which combines the so-called Empirical Mode Decomposition (EMD) multiresolution analysis and the Hilbert transform has proven its efficiency for the analysis of transient oscillatory signals, although the mathematical definition of the EMD is not totally established yet. HHT also provides an interesting alternative to other time-frequency or time-scale analysis of non-stationary signals, the most famous of which being wavelet-based approaches. In this application of HHT to the analysis of the hydrological variability of the Seine river, we seek to characterize the interannual patterns of daily flow, differenciate them from the short-term dynamics and eventually interpret them in the context of regional climate regime fluctuations. In this aim, HHT is also applied to the North-Atlantic Oscillation (NAO) through the annual winter-months NAO index time series. For both hydrological and climatic signals, dominant variability scales are extracted and their temporal variations analyzed by determination of the intantaneous frequency of each component. When compared to previous ones obtained from continuous wavelet transform (CWT) on the same data, HHT results highlighted the same scales and somewhat the same internal components for each signal. However, HHT allowed the identification and extraction of much more similar features during the 1950-2008 period (e.g., around 7-yr, between NAO and Seine flow than what was obtained from CWT, which comes to say that variability scales in flow likely to originate from climatic regime fluctuations were much properly identified in river flow. In addition, a more accurate determination of singularities in the natural processes analyzed were authorized by HHT compared to CWT, in which case the time-frequency resolution partly depends on the basic properties of the filter (i.e., the reference wavelet chosen initially). Compared to CWT or even to discrete wavelet multiresolution analysis, HHT is auto-adaptive, non-parametric, allows an orthogonal decomposition of the signal analyzed and provides a more accurate estimation of changing variability scales across time for highly transient signals.

Massei, N.; Fournier, M.

2010-12-01

109

Ma Huang and the Ephedra Alkaloids  

Microsoft Academic Search

Ephedra has been used as a natural medicine for thousands of years by numerous cultures with very little concern about toxicity.\\u000a Its most recent popularity is related to its purported “weight loss” or “performance enhancing” attributes. In spite of that\\u000a in 2004, concerns over safety resulted in the banning of all over-the-counter (OTC) sales of ephedra-containing dietary supplements\\u000a by the

Steven B. Karch

110

Simulation of Flood and Sediment Routing in the Pa-Chang River and the Pu-Tze River of Taiwan using CCHE1D Model  

Microsoft Academic Search

This paper presents the results of a study to determine the capability of a computational simulation model, CCHE1D, for simulating unsteady flow, sediment transport and morphodynamic processes in natural rivers during flood propagation. The results convincingly confirmed that the CCHE1D is capable of predicting the water elevations, the flow discharges and the morphodynamic changes of the main streams of two

Sam S. Y. Wang; Weiming Wu; Han-Min Hsia; Chang-Chi Cheng

111

A catalogue of Paschen-line profiles (Huang+, 2012)  

NASA Astrophysics Data System (ADS)

This catalogue contains spectroscopic data of 90 stars. A wide variety of stars were observed at H-? and at P-?. A few stars were observed at P-?. Most of the data were obtained at the Dominion Astrophysical Observatory (DAO). The remainder of the data were obtained at the Apache Point Observatory. (4 data files).

Huang, W.; Wallerstein, G.; Stone, M.

2012-09-01

112

Shiew-Mei Huang: Regulatory Issues - An FDA Perspective  

Center for Drug Evaluation (CDER)

Text Version... FDA OCP Transporter Scientific Interest Group continuing research to define/refine in vitro ... Are the FDA refined criteria optimal? Page 17. 17 ... More results from www.fda.gov/downloads/drugs/developmentapprovalprocess

113

The bearing fault diagnosis of rotating machinery by using Hilbert-Huang transform  

Microsoft Academic Search

Based on improve the drawbacks of Ensemble Empirical Mode Decomposition (EEMD), such as mode mixing and end effect problem, post-processing of EEMD which was improved with HHT approach to solve the problem in this paper. Once the Intrinsic Mode Functions (IMFs) are obtained from the decomposition process, the crucial step is to extract the fault features from the information-contained IMFs.

Tian-Yau Wu; Chun-Chieh Wang; Yu-Liang Chung

2011-01-01

114

Human activity classification using Hilbert-Huang transform analysis of radar Doppler data  

NASA Astrophysics Data System (ADS)

The automatic identification of human activities has become an area of interest in recent years. Identifying human activities is useful in various applications, such as through-barrier identification of intruders and non-contact monitoring of patients in hospitals. Numerous methods of human activity classification have been proposed in the past, including the use of Artificial Neural Networks (ANNs) and Support Vector Machines (SVMs). Most research in this area thus far has utilized the Short-Time Fourier Transform (STFT) as a method of obtaining the feature vectors necessary for classification. In this paper, we propose the use of the Empirical Mode Decomposition (EMD) algorithm as an alternative approach for obtaining feature vectors from human micro-Doppler signals and utilize an SVM for classification. Since the micro-Doppler signature is unique to a specific activity, the EMD outputs can be utilized as feature vectors. By utilizing the EMD algorithm in conjunction with an SVM, binary classification of human activities have shown to yield accurate results. Because SVMs were originally developed to solve the binary classification problem, additional steps must be taken in order to extend the problem to identify multiple classes. In this paper, two methods for multi-class classification will be demonstrated and compared. The first method is the one-against-all approach and the second is a decision tree based approach. In both cases, a high degree of accuracy is achieved.

Fairchild, Dustin P.; Narayanan, Ram M.

2011-05-01

115

Analysis of Hu-Huang-Fan Practical Hierarchical Identity-Based Encryption Scheme  

NASA Astrophysics Data System (ADS)

Recently, Hu et al. have suggested a fully secure hierarchical identity-based encryption (HIBE) scheme that achieves constant size ciphertext and tight security reduction. Their construction was based on Gentry's IBE scheme that supports their security proof. In this paper, we show that their security proof is incorrect. We point out the difference between Gentry's proof and that of Hu et al., and we show that the security of Hu et al.'s HIBE scheme cannot be reduced to their claimed complexity assumption.

Park, Jong Hwan; Lee, Dong Hoon

116

Crop yield responses to climate change in the Huang-Huai-Hai Plain of China  

Microsoft Academic Search

Global climate change may impact grain production as atmospheric conditions and water supply change, particularly intensive cropping, such as double wheat–maize systems. The effects of climate change on grain production of a winter wheat–summer maize cropping system were investigated, corresponding to the temperature rising 2 and 5°C, precipitation increasing and decreasing by 15% and 30%, and atmospheric CO2 enriching to

Suxia Liu; Xingguo Mo; Zhonghui Lin; Yueqing Xu; Jinjun Ji; Gang Wen; Jeff Richey

2010-01-01

117

Screening of obstructive sleep apnea using Hilbert–Huang decomposition of oronasal airway pressure recordings  

Microsoft Academic Search

Polysomnographic signals are usually recorded from patients exhibiting symptoms related to sleep disorders such as obstructive sleep apnea (OSA). Analysis of polysomnographic data allows for the determination of the type and severity of sleep apnea or other sleep-related disorders by a specialist or technician. The usual procedure entails an overnight recording several hours long. This paper presents a methodology to

P. Caseiro; R. Fonseca-Pinto; A. Andrade

2010-01-01

118

A Novel Preprocessing Method Using Hilbert Huang Transform for MALDI-TOF and SELDI-TOF Mass Spectrometry Data  

Microsoft Academic Search

MotivationMass spectrometry is a high throughput, fast, and accurate method of protein analysis. Using the peaks detected in spectra, we can compare a normal group with a disease group. However, the spectrum is complicated by scale shifting and is also full of noise. Such shifting makes the spectra non-stationary and need to align before comparison. Consequently, the preprocessing of the

Li-Ching Wu; Hsin-Hao Chen; Jorng-Tzong Horng; Chen Lin; Norden E. Huang; Yu-Che Cheng; Kuang-Fu Cheng; William C. S. Cho

2010-01-01

119

The huang-you star of the song dynasty-a chinese star list of the early medieval period  

NASA Astrophysics Data System (ADS)

Records of observations of stars (including the determinatives of the 28 lunar mansions) have been collected and re-edited from five previous editions. After further consulting the star chart of XYXFY and the Suzhou planisphere, we obtain the definitive positions of 360 stars which we can convert into the right ascensions and declinations for 1052 A.D., and hence their identification. Of the traditional 282 asterisms comprising 1464 stars, this list has 282 asterisms comprising 1457 stars, lacking only the star Shaocheng on the left Wall of the Purple Enclosure and the 6 stars of the asterism Ligong. With positions based on actual observations, this list embodies the traditional Chinese star system. It is the second listing after the ``Star List of Master Shi'' of the Warring Period, and provides an important and reliable reference for historical researches. All old Chinese texsts will be known by abbreviations. Full titles etc. are given at the end.

Pan, Nai; Wang, De-Chang

1981-12-01

120

Response characteristic analysis of climate change of vegetation activity in Huang-Huai-Hai area based on NOAA NDVI data set  

NASA Astrophysics Data System (ADS)

Based on 1982-2003 GIMMS NDVI soundings and climate data by use of techniques for the trend, correlation and SVD analysis, this work is devoted to the space/time patterns of the response to climate change of the vegetation activity in the Huan-Huai-Hai area (HHHA). Results suggest that the area shows a more significant warming trend and less distinct aridization, on the whole, with annual mean NDVI displaying a marginally increasing trend. On a yearly basis, NDVI is the most sensitive to climate factors, and annual temperature, rainfall and relative humidity (evaporation) exert positive (negative) effect on the dynamic variation in vegetation NDVI. On a seasonal scale, temperature and rainfall are the most strongly influencing factors, with autumnal climate having heavier impact on yearly mean NDVI. Natural vegetation is predominantly sensitive to rainfall and, to a less degree, to temperature; agricultural vegetation is sensitive dominantly to temperature and, to less extent, to rainfall. April - September vegetation response to climate has the space patterns as follows. The anomaly field of NDVI has 1) the same structure as that of temperature, 2) an anti-correlation structure with anomalies of evaporation, 3) a see-saw distribution with positive (negative) correlation in the north (south) with that of rainfall anomalies, and 4) an opposite distribution with positive (negative) correlations in the south (north) to that of relative humidity.

Li, Zhangjun; Sun, Zhaobo; Chen, Huailiang; Du, Zixuan; Zou, Chunhui

2007-10-01

121

A Fault Line-Selection Method of Hybrid Cable-Overhead Line in Distribution Network Based on Morphology Filter and Hilbert-Huang Transform  

Microsoft Academic Search

While the hybrid transmission lines of distribution network occur the single line to ground faults, a fault line detecting method with HHT detective then compare the phase relation based on the phase relation of zero sequence current between fault line and unfault line is reverse. A morphological filter is first developed to filter noise in transient zero sequence currents. Applying

Shu Hong-Chun; Zhao Wen-Yuan

2009-01-01

122

Empirical study of the scaling behavior of the amplitude–frequency distribution of the Hilbert–Huang transform and its application in sunspot time series analysis  

NASA Astrophysics Data System (ADS)

Investigating long-range correlation by the Hurst exponent, H, is crucial in the study of time series. Recently, empirical-mode-decomposition-based arbitrary-order Hilbert spectral analysis (EMD-HSA) has been proposed to numerically obtain without proof a scaling relationship, generated from the amplitude–frequency distribution, related to H. We propose a formalism to empirically study EMD-HSA, to deduce its scaling exponent ?(q) from the perspective of EMD-based arbitrary-order Hilbert marginal spectrum (EMD-HMS), and to numerically compare the results with the expected H. EMD-HSA and EMD-HMS experiments show that, by incompletely removing (quasi-)periodic trends, the sunspot series should have an H value around 0.12.

Zhou, Yu; Leung, Yee; Ma, Jian-Min

2013-03-01

123

Gold for ubiquitin in Vancouver: First Conference on Proteomics of Protein Degradation and Ubiquitin Pathways held June 6-8, 2010 in Vancouver, University of British Columbia, organized By Lan Huang, Thibault Mayor, and Peipei Ping.  

PubMed

The rise of proteomics has had tremendous influence on analysis and understanding of the role of post-translational modifications in biological processes. The covalent attachment of small proteins like ubiquitin, SUMO,(1) or other ubiquitin-like proteins (Ubls) is one class of post-translational modifications where proteomics has had notable impact. Various proteomics approaches, but in particular mass spectrometry-based analyses, have influenced the field and enabled significant advances over the past few years. The first meeting dedicated to proteomics of protein degradation and ubiquitin pathways showcased these advances and allowed a glimpse at future contributions of proteomics to this field. With its many attractive drug targets, the ubiquitin and proteasome system, as well as other proteolysis pathways, could offer new therapies for various human diseases including cancer and neurodegenerative disorders. The covalent linkage of ubiquitin to other proteins is catalyzed by the E1-E2-E3 cascade of enzymatic reactions whereby the many different E3 ubiquitin ligases provide substrate specificity to the process of protein ubiquitylation (1). Ubiquitylation is best known for targeting proteins for degradation by the proteasome, but other functions for ubiquitylation independent of proteolysis are also known. Likewise, modifications with SUMO or other Ubls generally do not regulate protein degradation but instead control subcellular localization, protein interactions, or change protein conformation and activity (2). The questions addressed by proteomics approaches to ubiquitylation and Ubl modifications are plentiful. They range from very specific, e.g. determination of the modified residue in a substrate protein, to complex, such as protein dynamics in proteome-wide ubiquitin (or Ubl) modification profiles (3). In either case, the rapid technological advancements (particularly in mass spectrometry instrumentation as well as quantitation and separation technologies) have allowed impressive progress, which was evident in the First Conference on Proteomics of Protein Degradation and Ubiquitin Pathways in Vancouver (http://ppdup.org/) (Fig. 1). PMID:20834021

Kaiser, Peter; Mayor, Thibault

2010-09-10

124

clinical Pharmacology AC meeting, Atlanta, GA  

Center for Drug Evaluation (CDER)

Text Version... Pharmacokinetics and Dose Adjustments in Renal Impairment Shiew-Mei Huang, PhD ... Atlanta, GA Page 2. 2 SM Huang 2010 Draft Renal Guidance ... More results from www.fda.gov/downloads/drugs/developmentapprovalprocess

125

Fake "Returnee" Earns 4 Million through Fraudulent Marriages: More than Ten Women Fall for His Claims of Being a Boss and Possessing a House and Car  

ERIC Educational Resources Information Center

|This article discusses the case of Wang Ruiliang. Ms. Huang filed a case against Wang Jun, alleging that he had defrauded her. Ms. Huang met a man named Wang Jun in April 2002 through a certain matrimonial agency. Before they had been together for very long, Wang Jun asked to borrow money from Ms. Huang, claiming that he was having difficulties…

Chinese Education and Society, 2005

2005-01-01

126

Engineering Mobile User Experience: Think. Design. Fail. Iterate. Publish  

Microsoft Academic Search

Der Vertrieb von Smartphone-Applikationen ?ber zentralisierte Marktpl?tze, wie Android Market, Apple iTunes oder Nokia Ovi Store ist heute fest etabliert. Dieser Vertriebsweg bietet Chancen, aber auch Risiken f?r die Entwickler: Die Nutzer erhalten einen direkten Feedbackkanal, auf dem sie Applikationen f?r alle anderen Nutzer sichtbar bewerten und kommentieren k?nnen. User Experience ist hier ein Schl?ssel zum Erfolg einer App. Gleichzeitig

Markus Heckner; Tim Schneidermeier; Alexander Bazo; Thomas Wagner; Thomas Wilhelm; Christian Wolff

2011-01-01

127

Zustandsänderungen idealer Gase mit endlicher Geschwindigkeit  

Microsoft Academic Search

Die Thermostatik ist die Lehre fiber das thermische Gleichgewicht yon Systemen; ihre Haupt,~htze fuP,,en auf einer axiomatischen Fassung der Erfahrungstatsac hen. Dutch die Haupts~tze sind die Bedingungen des G 1 e i c h g e w i c h t e s gegeben, und es wird auch (lie Richtung angegeben, in welcher sich das Gleichgewieht unter gewissen 5uBeren Bedingungen

L. Vahl

1933-01-01

128

Decontamination of chemical and biological warfare (CBW) agents using an atmospheric pressure plasma jet (APPJ)  

Microsoft Academic Search

The atmospheric pressure plasma jet (APPJ) [A. Schu¨tze &etal;, IEEE Trans. Plasma Sci. 26, 1685 (1998)] is a nonthermal, high pressure, uniform glow plasma discharge that produces a high velocity effluent stream of highly reactive chemical species. The discharge operates on a feedstock gas (e.g., He\\/O2\\/H2O), which flows between an outer, grounded, cylindrical electrode and an inner, coaxial electrode powered

H. W. Herrmann; I. Henins; G. S. Selwyn

1999-01-01

129

Achtsamkeit: Konzeptuelle Aspekte und Ergebnisse zum Freiburger Achtsamkeitsfragebogen  

Microsoft Academic Search

Einleitung: Im Rahmen verhaltenstherapeutischer und verhaltensmedizinischer Ans?tze wurde dem Prinzip Achtsamkeit (?Mindfulness?) in den letzten Jahren verst?rkt Aufmerksamkeit geschenkt: Neben der achtsamkeitsbasierten Stressreduktion nach Kabat-Zinn wurde von Segal, Williams und Teasdale die achtsamkeitsbasierte kognitive Therapie entwickelt. Bis vor wenigen Jahren gab es keine evaluierten psychometrischen Instrumente zur empirischen Erfassung von Achtsamkeit. In diesem Beitrag werden mehrere neu entwickelte Verfahren vorgestellt:

Thomas Heidenreich; Johannes Michalak

2006-01-01

130

Coordination versus coupling of dicyanamide in molybdenum and manganese pyrazole complexes.  

PubMed

The reactions of cis-[MoCl(?(3)-methallyl)(CO)(2)(NCMe)(2)] (methallyl = CH(2)C(CH(3))CH(2)) with Na(NCNCN) and pz*H (pzH, pyrazole, or dmpzH, 3,5-dimethylpyrazole) lead to cis-[Mo(?(3)-methallyl)(CO)(2)(pz*H)(?-NCNCN-?(2)N,N)](2) (pzH, 1a; dmpzH, 1b), where dicyanamide is coordinated as bridging ligand. Similar reactions with fac-[MnBr(CO)(3)(NCMe)(2)] lead to the pyrazolylamidino complexes fac-[Mn(pz*H)(CO)(3)(NH?C(pz*)NCN-?(2)N,N)] (pzH, 2a; dmpzH, 2b), resulting from the coupling of pyrazol with one of the CN bonds of dicyanamide. The second CN bond of dicyanamide in 2a undergoes a second coupling with pyrazole after addition of 1 equiv of fac-[MnBr(CO)(3)(pzH)(2)], yielding the dinuclear doubly coupled complex [{fac-Mn(pzH)(CO)(3)}(2)(?-NH?C(pz)NC(pz)=NH-?(4)N,N,N,N)]Br (3). The crystal structure of 3 reveals the presence of two isomers, cis or trans, depending on whether the terminal pyrazoles are coordinated at the same or at different sides of the approximate plane defined by the bridging bis-amidine ligand. Only the cis isomer is detected in the crystal structure of the perchlorate salt of the same bimetallic cation (4), obtained by metathesis with AgClO(4). All the N-bound hydrogen atoms of the cations in 3 or 4 are involved in hydrogen bonds. Some of the C-N bonds of the pyrazolylamidino ligand have a character intermediate between single and double, and theoretical studies were carried out on 2a and 3 to confirm its electronic origin and discard packing effects. Calculations also show the essential role of bromide in the planarity of the tetradentate ligand in the bimetallic complex 3. PMID:22583336

Arroyo, Marta; Gómez-Iglesias, Patricia; Martín-Alvarez, Jose Miguel; Alvarez, Celedonio M; Miguel, Daniel; Villafañe, Fernando

2012-05-15

131

Heavy alkaline earth metal pyrazolates: synthetic pathways, structural trends, and comparison with divalent lanthanoids.  

PubMed

Two series of heavy alkaline earth metal pyrazolates, [M(Ph(2)pz)(2)(thf)(4)] 1 a-c (Ph(2)pz=3,5-diphenylpyrazolate, M=Ca, Sr, Ba; THF=tetrahydrofuran) and [M(Ph(2)pz)(2)(dme)(n)] (M=Ca, 2 a, Sr, 2 b, n=2; M=Ba, 2 c, n=3; DME=1,2-dimethoxyethane) have been prepared by redox transmetallation/ligand exchange utilizing Hg(C(6)F(5))(2). Compounds 1 a and 2 b were also obtained by redox transmetallation with Tl(Ph(2)pz). Alternatively, direct reaction of the alkaline earth metals with 3,5-diphenylpyrazole at elevated temperatures under solventless conditions yielded compounds 1 a-c and 2 a-c upon extraction with THF or DME. By contrast, [M(Me(2)pz)(2)(Me(2)pzH)(4)] 3 a-c (M=Ca, Sr, Ba; Me(2)pzH=3,5-dimethylpyrazole) were prepared by protolysis of [M[N(SiMe(3))(2)](2)(thf)(2)] (M=Ca, Sr, Ba) with Me(2)pzH in THF and by direct metallation with Me(2)pzH in liquid NH(3)/THF. Compounds 1 a-c and 2 a-c display eta(2)-bonded pyrazolate ligands, while 3 a,b exhibit eta(1)-coordination. Complexes 1 a-c have transoid Ph(2)pz ligands and an overall coordination number of eight with a switch from mutually coplanar Ph(2)pz ligands in 1 a,b to perpendicular in 1 c. In eight coordinate 2 a,b the pyrazolate ligands are cisoid, whilst 2 c has an additional DME ligand and a metal coordination number of ten. By contrast, 3 a,b have octahedral geometry with four eta(1)-Me(2)pzH donors, which are hydrogen-bonded to the uncoordinated nitrogen atoms of the two trans Me(2)pz ligands. The application of synthetic routes initially developed for the preparation of lanthanoid pyrazolates provides detailed insight into the similarities and differences between the two groups of metals and structures of their complexes. PMID:15224341

Hitzbleck, Julia; O'Brien, Anna Y; Forsyth, Craig M; Deacon, Glen B; Ruhlandt-Senge, Karin

2004-07-01

132

Neonatal Jaundice — Traditional Chinese Medicine Approach  

Microsoft Academic Search

Herbal treatment of neonatal jaundice (NNJ) has been practiced in China for a long time. Even to-date, a variety of herbal items, including “Yin-chin” (Artemisia), “Huang-qin” (Scutellaria), “Da-huang” (Rheum officinale), “Gan-cao” (Glycyrrhiza), and “Huang-lin” (Coptis chinesis), are still being prescribed to jaundiced infants, often in combination with modern treatment such as phototherapy and exchange transfusion. Their efficacy has, however, not

Tai Fai Fok

2001-01-01

133

Polaron dynamics in two-dimensional photon-echo spectroscopy of molecular rings.  

PubMed

We have developed a new approach to the computation of third-order spectroscopic signals of molecular rings, by incorporating the Davydov soliton theory into the nonlinear response function formalism. The Davydov D1 and D? Ansa?tze have been employed to treat the interactions between the excitons and the primary phonons, allowing for a full description of arbitrary exciton-phonon coupling strengths. As an illustration, we have simulated a series of optical 2D spectra for two models of molecular rings. PMID:24050324

Huynh, Thanh Duc; Sun, Ke-Wei; Gelin, Maxim; Zhao, Yang

2013-09-14

134

Method of Removing Noise from EEG Signals Based on HHT Method  

Microsoft Academic Search

Many noises are interfused into EEG signals when they are measuring. In order to remove the noises effectively, a novel method based on Hilbert Huang Transform, is shown in the thesis. The theories of empirical mode decomposition and instantaneous frequency solution which are two parts of Hilbert-Huang Transformation are discussed in the thesis. Empirical mode decomposion is used to EEG

Lihong Zhang; Dingyun Wu; Lianhe Zhi

2009-01-01

135

Debt Valuation with Endogenous Default and Chapter 11 Reorganization  

Microsoft Academic Search

We examine a continuous-time structural model of debt valuation with endogenous default and Chapter 11 bankruptcy. Focusing on exclusivity rules, we model the bar- gaining process in Chapter 11 as the debtor's ultimatum oers to the creditors and calibrate the model using an approach similar to that of Huang and Huang (2002)(20). Credit spreads and expected Chapter 11 duration are

Alex Paseka

136

Paper Evaluation: Securing Web Application Code by Static Anaylysis and Runtime Protection  

Microsoft Academic Search

Evaluation paper of Securing Web Application Code by Static Analysis and Runtime Protection by Huang et al. from 2004 (HYH+04b) attempting to go further in solving web application vulnerabilities in the source code at compile time. This paper explains the concepts and solutions proposed by Huang et al. and also attempts to fully evaluate and discuss its merits and failures,

Michael England

2008-01-01

137

From the polycyclicity theory to open-and-close tectonics  

Microsoft Academic Search

Professor Huang Jiqing (T. K. Huang) put forward the concept of polycyclic tectonic movement which was developed into the polycyclicity theory that is influential all over the world. This paper outlines the basics of this theory.The present author tries to distinguish between two kinds of polycyclic tectonic movements: in situ superimposition and recurrence in other places according to whether or

Jiang Chunfa

1996-01-01

138

Poly(pyrazolyl)aluminate complexes containing aluminum-hydrogen bonds.  

PubMed

The treatment of LiAlH(4) with 2, 3, or 4 equiv of the 3,5-disubstituted pyrazoles Ph(2)pzH or iPr(2)pzH afforded [Li(THF)(2)][AlH(2)(Ph(2)pz)(2)] (97%), [Li(THF)][AlH(Ph(2)pz)(3)] (96%), [Li(THF)(4)][Al(Ph(2)pz)(4)] (95%), and [Li(THF)][AlH(iPr(2)pz)(3)] (89%). The treatment of ZnCl(2) with [Li(THF)][AlH(Ph(2)pz)(3)] afforded Zn(AlH(Ph(2)Pz)(3))H (70%). X-ray crystal structures of these complexes demonstrated ?(2) or ?(3) coordination of the aluminum-based ligands to the Li or Zn ions. The treatment of [Li(THF)][AlH(Ph(2)pz)(3)] with MgBr(2) or CoCl(2) in THF/Et(2)O solutions, by contrast, afforded the pyrazolate transfer products Mg(2)Br(2)(Ph(2)pz)(2)(THF)(3)·2THF (25%) and Co(2)Cl(2)(Ph(2)pz)(2)(THF)(3)·THF (23%) as colorless and blue crystalline solids, respectively. An analogous treatment of [Li(THF)][AlH(Ph(2)pz)(3)] with MCl(2) (M = Mn, Fe, Ni, Cu) afforded metal powders and H(2), illustrating hydride transfer from Al to M as a competing reaction path. PMID:21877698

Snyder, Christopher J; Heeg, Mary Jane; Winter, Charles H

2011-08-30

139

[Detection and identification of highly pathogenic bacteria within the framework of the EQADeBa project--Part I: Samples containing living pathogens].  

PubMed

Bacillus anthracis, Yersinia pestis, Francisella tularensis, Brucella sp., Bulkholderia mallei are B. pseudomallei are highly pathogenic bacteria of potential bioterrorism risk. To support the early warning and rapid response capacity to ensure an effective reaction to bioterrorist attacks the international project "Establishment of Quality Assurances for Detection of Highly Pathogenic Bacteria of Potential Bioterrorism Risk" (EQADeBa) has been established. The aim of the project was establishment the network of European laboratories that possess a suitable infrastructure and experts and laboratory workers trained in detection and identification of the highly pathogenic bacteria. This work presents methods used in investigation of samples containing living pathogens and results obtained in Department of Bacteriology NIZP-PZH in the third international test organized within the framework of the EQADeBa. The test evaluated competence of laboratories in detection and identification of pathogens mentioned above. In the work methods used in other laboratories were discussed and the results were compared. Results of the test confirmed competence of NIZP-PZH in detection and identification of highly pathogenic bacteria covered by EQADeBa project. PMID:22184939

Zasada, Aleksandra A; Gierczy?ski, Rafa?; Rzeczkowska, Magdalena; Formi?ska, Kamila; Zacharczuk, Katarzyna; Rastawicki, Waldemar

2011-01-01

140

Mathematically rigorous formulation of the Fermi pseudopotential for higher-partial-wave scattering in arbitrary dimension  

SciTech Connect

The Huang-Yang multipolar pseudopotential [see Huang and Yang, Phys. Rev. 105, 767 (1957); later revised by Huang, Statistical Mechanics (Wiley, New York, 1963)] is derived in a mathematically rigorous way using distribution theory in arbitrary dimension. For higher partial waves (i.e., all except s waves), the original pseudopotential contained wrong numerical factors in dimension 3, which were corrected only recently [see Derevianko, Phys. Rev. A 72, 044701 (2005); Stampfer and Wagner, J. Math. Anal. Appl. 342, 202 (2008)]. Here, we generalize the expression for the pseudopotential, in particular to even dimension, enabling the study of scattering processes in a large class of systems, especially in dimension 2.

Stampfer, F.; Wagner, P. [University of Innsbruck, Technikerstrasse 13, A-6020 Innsbruck (Austria)

2010-05-15

141

Treesearch - Forest Service Research & Development  

Treesearch

Sep 21, 2012 ... Cole, David N.; Hall, Troy E. 2010, -- ... Zone-tailed Hawk (Buteo albonotatus), Stoleson, Scott H.; Sadoti, Giancarlo, 2010, -- ... Curtis H.; Huang, Chengquan; Masek, Jeffrey G.; Stewart, Susan I.; Radeloff, Volker C. 2010, --.

142

Cover: journal of basic microbiology. 8/2013.  

PubMed

Cover illustration: The antibiotics produced by a biocontrol agent Bacillus pumilus SQR-N43 induced hyphal deformation and enlargement of cytoplasmic vacuoles in Rhizoctonia solani Q1 mycelium. (Photo: Xinqi Huang, Nanjing, China). PMID:23943200

2013-08-01

143

Evaluating Complex DDI Using Modeling And Simulations ...  

Center for Drug Evaluation (CDER)

Text Version... And Simulations: Application and Challenge in Regulatory Review Ping Zhao, Lei Zhang, Lawrence Lesko, Shiew-Mei Huang ... More results from www.fda.gov/downloads/drugs/developmentapprovalprocess

144

MRSA Screening  

MedlinePLUS

... for Current Review Susan S. Huang, et al. Targeted versus Universal Decolonization to Prevent ICU Infection. NEJM 368; ... Updated 2009 December 16). MRSA Skin Infection in Athletes. eMedicine [On-line information]. Available online at http:// ...

145

US Food and Drug Administration Notice: Archived Document  

Center for Drug Evaluation (CDER)

Text VersionPage 1. US Food and Drug Administration ... OTS presentation, May 2009 (modified) Page 19. 18 SM Huang ... Updating labeling Genetic Data?? ... More results from www.fda.gov/downloads/drugs/developmentapprovalprocess

146

US Food and Drug Administration Notice: Archived Document  

Center for Drug Evaluation (CDER)

Text Version... based on exposure-response data/analyses 6. Labeling language needs to be useful ... 9 Shiew-Mei Huang International Transporter Working Group ... More results from www.fda.gov/downloads/drugs/developmentapprovalprocess

147

Clinical Pharmacology AC meeting  

Center for Drug Evaluation (CDER)

Text Version... 2. Huang, Abraham,Apparaju,Atkinson, Burckart, Lee, Roy, Strong, Xiao, Wu, Zhang, ... MDRD (Modified Diet in Renal Disease) ... More results from www.fda.gov/downloads/drugs/developmentapprovalprocess

148

US Food and Drug Administration Notice: Archived Document  

Center for Biologics Evaluation and Research (CBER)

Text Version... 13 Page 15. systems. In Food Phytochemical for Cancer Prevention. I. Fruits and Vegetables; Huang, MT, Osawa, T., Ho, CT, Rosen, RT, Eds. ... More results from www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials

149

FDA Critical Path Transporter Workshop  

Center for Drug Evaluation (CDER)

Text Version... Indiana U David Flockhart Steve Hall Page 8. 7 Shiew-Mei Huang ... Practice,” Ed. Waldman & Terzic, Elsevier (in press) Selected efflux & uptake ... More results from www.fda.gov/downloads/drugs/developmentapprovalprocess

150

Midcycle Meeting, March 29, 2012 - SOLX® System  

Center for Biologics Evaluation and Research (CBER)

... OCBQ/DIS/BMB DMPQ: Ellen Huang, OCBQ/DMPQ/BII Marion Michaelis, OCBQ/DMPQ/BII Labeling: Lore Fields, OBRR/DBA/BPB Dana Martin ... More results from www.fda.gov/biologicsbloodvaccines/bloodbloodproducts/approvedproducts

151

75 FR 60461 - Agency Information Collection Activities: Proposed Collection; Comment Request  

Federal Register 2010, 2011, 2012, 2013

...Alarmingly, 70% of HAIs are due to bacteria that are resistant to commonly used antibiotics (Huang 2007). This project is designed...duration and route of administration of antibiotics. Using antibiotics appropriately can potentially...

2010-09-30

152

75 FR 43169 - Agency Information Collection Activities: Proposed Collection; Comment Request  

Federal Register 2010, 2011, 2012, 2013

...Alarmingly, 70% of HAIs are due to bacteria that are resistant to commonly used antibiotics (Huang 2007). This project is designed...duration and route of administration of antibiotics. Using antibiotics appropriately can potentially...

2010-07-23

153

Kinematic and Clinical Analyses of Upper-Extremity Movements After Constraint-Induced Movement Therapy in Patients With Stroke: A Randomized Controlled Trial  

Microsoft Academic Search

Wu CY, Chen CL, Tang SF, Lin KC, Huang YY. Kinematic and clinical analyses of upper-extremity movements after constraint-induced movement therapy in patients with stroke: a randomized controlled trial.

Ching-yi Wu; Chia-ling Chen; Simon F. Tang; Keh-chung Lin; Ya-ying Huang

2007-01-01

154

Neuropsychological deficits of a U.S. Army pilot following an anoxic event as a function of cardiac arrest.  

PubMed

Anoxic encephalopathy occurs as a result of cardiac arrest, respiratory distress, or carbon monoxide poisoning. This is a case report on the neuropsychological deficits of anoxia in an otherwise previously healthy 36-year-old male pilot. The patient was taking an over-the-counter supplement that included an herb called Ma Huang on the day of his cardiac arrest. Ma Huang is reported to potentially present an increased risk of cardiac infarctions and central nervous system dysfunctions. Several instances of death have been linked to Ma Huang. The patient produced a neuropsychological profile that evidenced impairments in executive functioning, memory, language, attention, intellectual and academic functioning, as well as motor speed and coordination, all of which are consistent with diffuse brain damage. This case adds to the body of literature documenting the physical and neuropsychological effects of anoxia, as well as the effects of ephedrine-based supplements, such as Ma Huang. PMID:14529256

Baggett, Mark R; Kelly, Mark P; Korenman, Lisa M; Ryan, Laurie M

2003-09-01

155

JSSX 25th Anniversary Symposium  

Center for Drug Evaluation (CDER)

Text Version... Use of Prescription/ OTC/Supplements Photo by Shiew-Mei Huang • 80% of individuals > 57 YO takes at least 1 medical product (prescription, ... More results from www.fda.gov/downloads/drugs/developmentapprovalprocess

156

Urban Latino African American Cancer (ULAAC) Disparities Project at Centinela Freeman Regional Medical Center  

Cancer.gov

Our Team Principal Investigator Michael Steinberg, MD Co-Principal Investigators David Khan, MD, Radiation Oncologist, CF David Huang, MD, Radiation Oncologist, CF Nell Forge, PhD, MPH, Assoc. Behavioral Scientist, RAND Allen Fremont, MD, PhD, Assoc.

157

Record of Telephone Conversation, August 15, 2012 am ...  

Center for Biologics Evaluation and Research (CBER)

... Flucelvax. Date/Time of Call: August 15, 2012 @ 9 AM. CBER Representative: Ellen Huang, CSO, CBER/OCBQ/DMPQ/MRBII. ... More results from www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts

158

OCEESA Journal, Volume 15, No. 1, January 1998.  

National Technical Information Service (NTIS)

The journal covers 10 papers, OCCESA President's message, and OCEESA Past President message. The 10 papers include (1) Sino-American Technology and Engineering Conference SATEC Report, John Chao-Piao Huang, (2) U.S. Environmental Protection Agency's Great...

Y. T. Hung S. Y. Chang C. T. Tien

1998-01-01

159

[Temperature-sensitive clones of herpes simplex virus type 1 from laboratory and clinical strains. I. Cloning and basic pathogenetic and immunogenic properties].  

PubMed

Two HSV-1 strains were used in the study: McIntyre laboratory strain and "eye" strain isolated from a patient. Temperature-sensitive clone of HSV-1 was isolated from McIntyre strain as a consequence of virus replication carried out at lowered temperature (28 degrees C). Temperature-resistant clones were obtained from both strains through passages at 39 degrees C and through heating for four times at 45 degrees C. Pathogenic properties of the temperature clones obtained were determined in inbred mice Balb/c and CFw/Pzh. A loss of pathogenicity for mice of temperature-sensitive clone and an increase of pathogenicity of temperature-resistant clones were noted as compared to parental strains. It was found that an introduction of temperature-sensitive clone, with lowered virulence immunizes against highly virulent temperature-resistant clone. PMID:1664472

Litwi?ska, B; Sadowski, W; Ka?toch, M

1991-01-01

160

Combustion-Supporting Effect of Common Carbonous Solid Waste on Anthracites  

NASA Astrophysics Data System (ADS)

In order to study the combustion characteristics of anthracite with additives, the influence of common carbonous solid waste (CSW) on anthracite is studied by thermogravimetry. The results show that appropriate CSW additives mixed with pulverized coal (PC) at PZH Steel can promote the combustion of PC and increase the burning ratio of anthracite greatly. The greater the additive content, the higher the burning ratio at the same conditions. The dynamics models show that the particle size of CSW additives, oxygen concentration, and the diffusion coefficient of oxygen are all very influential for their combustion characteristics. The heat of CSW combustion is absorbed by coal powder, and it consists of part of the coal powder accumulated heat. Then, accumulated heat is higher than dissipation heat ahead of time, so CSW can support combustion of coal powder effectively.

Zhang, Jianliang; Ren, Shan; Liu, Zhengjian; Zhou, Yun; Meng, Fanyi; Su, Buxin

2012-08-01

161

A note on the integrability of the classical portfolio selection model  

Microsoft Academic Search

We revisit the classical Merton portfolio selection model from the perspective of integrability analysis. By an application of a nonlocal transformation the nonlinear partial differential equation for the two-asset model is mapped into a linear option valuation equation with a consumption dependent source term. This result is identical to the one obtained by Cox–Huang [J.C. Cox, C.-f. Huang, Optimal consumption

V. Naicker; J. G. O’Hara; P. G. L. Leach

2010-01-01

162

Some notes on the paper “Cone metric spaces and fixed point theorems of contractive mappings”  

Microsoft Academic Search

Huang and Zhang reviewed cone metric spaces in 2007 [Huang Long-Guang, Zhang Xian, Cone metric spaces and fixed point theorems of contractive mappings, J. Math. Anal. Appl. 332 (2007) 1468–1476]. We shall prove that there are no normal cones with normal constant M1 and for each k>1 there are cones with normal constant M>k. Also, by providing non-normal cones and

Sh. Rezapour; R. Hamlbarani

2008-01-01

163

Determination of the correlation between mechanical, acoustic characteristics and electromagnetic parameters of porous metals  

SciTech Connect

The use of products made of porous materials with inhomogeneous structure makes it necessary to work out methods for the complex diagnostics of their properties during production and in operation. To solve this problem we have to establish reliable correlations between the mechanical, strength, acoustic characteristics determining the operation of the products and the electrical and magnetic parameters of the materials used in combined methods of testing and quality control. The aim of the present work is to establish such correlations for porous iron which is widely used as structural material. For the measurement we made specimens of powdered iron of the industrial marques PZh4M2 and PZhRV2 by pressing and subsequent sintering in vacuum at 1540 K for 2.5 h. The modulus of elasticity E, the shear modulus G, and the bulk modulus B were determined from the speeds of the longitudinal C{sub l} and transverse C{sub t} ultrasonic waves. The electromagnetic values of the investigated specimens were found on the basis of the eddy-current method using a superposed sensor by measuring the resonance parameters of the oscillating circuit. The results of measurements, averaged over 10 specimens with similar porosity, were presented in a form suitable for analysis. It can be seen that the correlation of hardness, the moduli of elasticity, and the speeds of ultrasound with relative magnetic permeability is stronger than with electrical conductivity. Preference should therefore be given to methods of testing and quality control based on the measurement of magnetic parameters.

Polyakov, V.V.; Golovin, A.V.; Egorov, A.V. [Altai State Univ., Barnaul (Russian Federation)

1994-06-01

164

Syntheses and luminescent properties of 3,5-diphenylpyrazolato-bridged heteropolynuclear platinum complexes. The influence of chloride ligands on the emission energy revealed by the systematic replacement of chloride ligands by 3,5-dimethylpyrazolate.  

PubMed

Heteropolynuclear Pt(II) complexes with 3,5-diphenylpyrazolate [Pt(2)Ag(4)(?-Cl)(2)(?-Ph(2)pz)(6)] (3), [Pt(2)Ag(2)Cl(2)(?-Ph(2)pz)(4)(Ph(2)pzH)(2)] (4), [Pt(2)Cu(2)Cl(2)(?-Ph(2)pz)(4)(Ph(2)pzH)(2)] (5), [Pt(2)Ag(4)(?-Cl)(?-Me(2)pz)(?-Ph(2)pz)(6)] (7), and [Pt(2)Ag(4)(?-Me(2)pz)(2)(?-Ph(2)pz)(6)] (8) have been prepared and structurally characterized. These complexes are luminescent except for 5 in the solid state at an ambient temperature with emissions of red-orange (3), orange (4), yellow-orange (7), and green (8) light, respectively. Systematic red shift of the emission energies with the number of chloride ligands was observed for 3, 7, and 8. DFT calculations indicate that the highest occupied molecular orbital (HOMO) as well as HOMO-1 of the heterohexanuclear complexes, 3, 7, and 8, having Pt(2)Ag(4) core, mainly consist of d? orbital of Pt(II) and ? orbitals of Ph(2)pz ligands, while the lowest unoccupied molecular orbital (LUMO) of these complexes mainly consists of in-phase combination of 6p of two Pt(II) centers and 5p of four Ag(I) centers. It is likely that the emissions of 3, 7, and 8 are attributed to emissive states derived from the Pt(2)(d)/? ? Pt(2)Ag(4) transitions, the emission energy of which depends on the ratio of chloride ligands to pyrazolate ligands. PMID:22775460

Akatsu, Seiji; Kanematsu, Yasunori; Kurihara, Taka-aki; Sueyoshi, Shota; Arikawa, Yasuhiro; Onishi, Masayoshi; Ishizaka, Shoji; Kitamura, Noboru; Nakao, Yoshihide; Sakaki, Shigeyoshi; Umakoshi, Keisuke

2012-07-09

165

Unitarity triangle and quark mass matrices on the nearest-neighbor interaction basis  

SciTech Connect

We examine the unitarity triangle of the KM matrix, which is derived from the general quark mass matrices in the NNI basis. The Fritzsch {ital Ans{umlt a}tze} are modified by introducing four additional parameters. The KM matrix elements are expressed in terms of quark mass ratios, two phases, and four additional parameters. It is found that the vertex of the unitarity triangle is predicted to be almost in the second quadrant on the {rho}-{eta} plane as far as V{sub us}{approx_equal}{minus}{radical}(m{sub d}/m{sub s})e{sup ip}+{radical}(m{sub u}/m{sub c})e{sup iq}. {copyright} {ital 1997} {ital The American Physical Society}

Ito, T. [Department of Physics, Nagoya University, Nagoya 464-01 (Japan); Tanimoto, M. [Science Education Laboratory, Ehime University, Matsuyama 790 (Japan)

1997-02-01

166

Ephedra and Its Application to Sport Performance: Another Concern for the Athletic Trainer?  

PubMed Central

Objective: The ma huang herb, otherwise known as ephedra, has gained widespread popularity as an ergogenic supplement. With the sympathomimetic alkaloid ephedrine as its primary active ingredient, ma huang is marketed to reduce fatigue; increase strength, power, and speed; decrease reaction time; and improve body composition. Although numerous side effects have been associated with the use of ma huang, its popularity in athletes continues to grow. This review provides rationale for the ergogenic claims regarding ma huang and compares and contrasts those claims with data from scientifically controlled investigations. Data Sources: MEDLINE and SPORT Discus were searched from 1970 to 2000 using the key words ma huang, ephedra, and ephedrine in combination with humans, exercise, performance, and side effects. Data Synthesis: Ephedrine has been used alone or in combination with other drugs as an effective weight-loss agent. The weight loss has been attributed to thermogenic and lipolytic effects which, in combination with the central nervous system stimulating effects, have also resulted in its use as an ergogenic aid. Most of the scientific data, however, do not support manufacturers' ergogenic claims, and numerous side effects have been associated with ephedrine use. Thus, the safety and efficacy of ma huang as an ergogenic supplement must be questioned. Conclusions/Recommendations: It appears that the risks associated with the use of ma huang far outweigh any possible ergogenic benefits. Thus, it is extremely important that athletic trainers educate athletes on these issues so they can continue to perform at an optimum level in a safe and healthy manner.

2001-01-01

167

A Weighted Rank-Sum Procedure for Comparing Samples with Multiple Endpoints  

PubMed Central

Summary For comparing the distribution of two samples with multiple endpoints, O’Brien (1984) proposed rank-sum-type test statistics. Huang et al. (2005) extended these statistics to the general nonparametric Behrens-Fisher hypothesis problem and obtained improved test statistics by replacing the ad hoc variance with the asymptotic variance of the rank-sum statistics. In this paper we generalize the work of O’Brien (1984) and Huang et al. (2005) and propose a weighted rank-sum statistic. We show that the weighted rank-sum statistic is asymptotically normally distributed, permitting the computation of power, p-values and confidence intervals. We further demonstrate via simulation that the weighted rank-sum statistic is efficient in controlling the type I error rate and under certain alternatives, is more powerful than the statistics of O’Brien (1984) and Huang et al.(2005).

Li, Qizhai; Liu, Aiyi; Yu, Kai; Yu, Kai F.

2009-01-01

168

A comparison of two Hilbert spectral analyses of heart rate variability.  

PubMed

The present paper compares the performance of two Hilbert spectral analyses when applied to a synthetic RR series from a nonstationary integral pulse frequency modulation model and to real RR series from a dataset of normal sinus arrhythmia. The Hilbert-Huang transformation based on empirical mode decomposition is compared to the presently introduced Hilbert-Olhede-Walden transformation based on stationary wavelet packet decomposition. The comparison gives consistent results pointing to a superior performance of the Hilbert-Olhede-Walden transformation showing 33-163 times smaller deviations when estimating the instantaneous frequency traces of the synthetic RR series. Artificial fluctuations caused by mode mixing in the Hilbert-Huang spectrum are seen in both the synthetic and real RR series. It can be concluded that the instantaneous frequencies and amplitudes estimated by the Hilbert-Huang transformation should be interpreted with caution when investigating heart rate variability. PMID:19521730

Ihlen, Espen Alexander Fürst

2009-06-12

169

Electron-lattice coupling in ZnFe2O4/TiO2 nanocomposite films  

NASA Astrophysics Data System (ADS)

Electron-lattice (e-ph) coupling originated from the low-temperature photoluminescence in ZnFe2O4/TiO2 nanocomposite films has been studied. The purely linear character of the e-ph coupling is shown through the Huang-Rhys model within the Franck-Condon approximation. The interfacial coupling capability between the ZnFe2O4 nanoparticles and the TiO2 host lattice is characterized by the Huang-Rhys factors (S0) and the vibrational quantum energy (??). It is found that the Huang-Rhys factors S0 increases with increasing the content of ZnFe2O4 in the TiO2 films and the vibrational energy ?? is quite in agreement with that in the infrared spectra.

Jin, Yunxia; Li, Guanghai; Zhang, Lide

2005-02-01

170

[Critical tidal level for planting Kandelia candel seedlings in Xiamen].  

PubMed

Plantable tidal flat is one of the most important factors affecting the survival rate of mangroves seedlings in forestation. In this paper, an experiment was conducted in the tidal zones of Umbrette Natural Reserve in the Dayu Island of Xiamen in May 2003 to investigate the critical tidal level for Kandelia candel forestation. The results showed that the tidal level of 0.99 m above the zero tidal level of the Huang Ocean was not suitable for planting K. candel seedlings, because the waterlogging time at this tidal level was longer than 8 h per-tide-cycle, and the survival rate was lower than 50% . At 1.62 m above the zero tidal level of Huang Ocean, K. candel seedlings had the best growth and the highest photosynthetic assimilation, with a survival rate of 90%. At 1.31 m above the zero tidal level of Huang Ocean, K. candel seedlings could still grow well. It could be concluded that the tidal level of 1.62 m was optimal for planting K. candel seedlings, and the critical tidal level of K. candel seedlings in the coastal areas of Xiamen was not lower than 1.31 m above the zero tidal level of Huang Ocean, where the waterlogging time was not longer than 5.6 h per-tide-cycle. PMID:16706033

Chen, Luzhen; Yang, Zhiwei; Wang, Wenqin; Lin, Peng

2006-02-01

171

INHIBITION OF RESPIRATORY SYNCYTIAL VIRUS (RSV)-INDUCED INFLAMMATION BY 3-NITROTYROSINE IN HUMAN BRONCHIAL EPITHELIAL CELLS  

EPA Science Inventory

Inhibition of Respiratory Syncytial Virus (RSV)-Induced Inflammation by 3-Nitrotyrosine in Human Bronchial Epithelial Cells. J. M. Soukup, MPH 1, ZW. Li, MD 2 and YC. T. Huang, MD 1. 1 NHEERL, US Environmental Protection Agency, RTP, NC and 2 CEMALB, University of North Carolina,...

172

NITROTYROSINE ATTENUATES RSV-INDUCED INFLAMMATION IN AIRWAY EPITHELIAL CELLS  

EPA Science Inventory

Nitrotyrosine attenuates RSV-induced inflammation in airway epithelial cells. Joleen Soukup, Zuowei Li, Susanne Becker and Yuh-Chin Huang. NHEERL, ORD, USEPA, RTP, North Carolina, CEMALB, University of North Carolina, Chapel Hill, North Carolina Nitrotyrosine (NO2Tyr) is a...

173

Evaluating the effect of temperature on microbial growth rate - the Ratkowsky and a Belehrádek type models  

Technology Transfer Automated Retrieval System (TEKTRAN)

The objective of this paper to conduct a parallel comparison of a new Belehradek-type growth rate (Huang model), Ratkowsky Square-root, and Ratkowsky Square equations as secondary models for evaluating the effect of temperature on the growth of microorganisms. Growth rates of psychrotrophs and meso...

174

Phosphorylation meets proteolysis.  

PubMed

Phosphorylation is a reversible post-translational modification that regulates many proteins and enzymes, including proteases, as shown by two recent publications. Huang and colleagues and Velázquez-Delgado and Hardy (this issue of Structure) describe how phosphorylation activates the protease activity of the deubiquitinating enzyme DUBA and how it inhibits caspase-6, respectively. PMID:22483104

Renatus, Martin; Farady, Christopher J

2012-04-03

175

NITROTYROSINATION OF A TUBULIN INDUCES EPITHELIAL BARRIER DYSFUNCTION  

EPA Science Inventory

Nitrotyrosination of a-Tubulin Induces Epithelial Transport Dysfunction. Yuh-Chin Huang, Lisa Dailey, Wen-Li Zhang and Ilona Jaspers. ORD, Environmental Protection Agency and CEMLB, University of North Carolina a-Tubulin undergoes a cyclic removal and readdition of tyrosin...

176

URBAN PARTICLE-INDUCED PULMONARY ARTERY CONSTRUCTION IS MEDIATED BY SUPEROXIDE PRODUCTION  

EPA Science Inventory

URBAN PARTICLE-INDUCED PULMONARY ARTERY CONSTRICTION IS MEDIATED BY SUPEROXIDE PRODUCTION.Jacqueline D. Carter, Zhuowei Li, Lisa A. Dailey, Yuh-Chin T. Huang. CEMALB, University of North Carolina, and ORD, US EPA, Chapel Hill, North Carolina. Exposure to particulate matter...

177

Short-Wave Aviation Communication Signal Analysis and Aircraft Classification  

Microsoft Academic Search

This paper investigates how to classify the type of the aircraft based on the aviation communication signal. Hilbert-Huang Transform (HHT) is introduced to adaptively decompose the cockpit voice into several IMFs, then the IMFs can be used as the features of the aircraft for identifying the type. To alleviate the problem of mode mixing caused by the signal intermittency in

Liu Feng; Li Xueyao; Liang Zhilan

2008-01-01

178

A new approach for crude oil price analysis based on Empirical Mode Decomposition  

Microsoft Academic Search

The importance of understanding the underlying characteristics of international crude oil price movements attracts much attention from academic researchers and business practitioners. Due to the intrinsic complexity of the oil market, however, most of them fail to produce consistently good results. Empirical Mode Decomposition (EMD), recently proposed by Huang et al., appears to be a novel data analysis method for

Xun Zhang; K. K. Lai; Shou-Yang Wang

2008-01-01

179

The EEG Signal Process Based on EEMD  

Microsoft Academic Search

Hilbert Huang Transform (HHT), which is based on EMD (Empirical Mode Decomposition) and Hilbert transform method, is a new signal analysis method. It suits for analyzing the non-linear and non-stationary signals, such as EEG signal particularly. The traditional EMD method has the Mode Mixing problem. Therefore a new method basing on Ensemble Empirical Mode Decomposition (EEMD) for processing the signal

Zhu Xiao-jun; Lv Shi-qin; Liu-juan Fan; Xue-li Yu

2011-01-01

180

Speaker Identification Using HHT Spectrum Features  

Microsoft Academic Search

This paper proposes new acoustical features based on Hilbert Huang transform (HHT) for speaker identification. HHT is a powerful analysis method to obtain instantaneous frequency (IF). First, empirical ensemble empirical mode decomposition (EEMD) is used to generate intrinsic mode functions (IMFs). The Hilbert transform is then applied to IMFs to compute the instantaneous frequencies. With the obtained instantaneous frequencies, two

Jia-Wei Liu; Jia-Ching Wang; Chang-Hong Lin

2011-01-01

181

Potential contrast improvement in ultrasound pulse inversion imaging using EMD and EEMD  

Microsoft Academic Search

Ultrasound nonlinear imaging using microbubble- based contrast agents has been widely investigated. Nonetheless, its contrast is often reduced by the nonlinearity of acoustic wave propagation in tissue. In this paper, we explore the use of empirical mode decomposition (EMD) and ensemble empirical mode decomposition (EEMD) in the Hilbert-Huang transform (HHT) for possible contrast improvement. The HHT is designed for analyzing

Ai-Ho Liao; Che-Chou Shen; Pai-Chi Li

2010-01-01

182

Contrast improvement by combining pulse inversion with EMD and EEMD  

Microsoft Academic Search

Ultrasound nonlinear contrast imaging often has limited contrast because acoustic wave propagation in tissue is also nonlinear. In this study, a new ultrasound contrast imaging method which combines pulse-inversion technique with empirical mode decomposition (EMD) and the ensemble empirical mode decomposition (EEMD) in Hilbert-Huang transform (HHT) is explored to enhance the contrast between bubbles and surrounding tissues. The EMD is

Ai-Ho Liao; Che-Chou Shen; Pai-Chi Li

2009-01-01

183

Automatic contrast enhancement using ensemble empirical mode decomposition  

Microsoft Academic Search

Abstract¿Ultrasound nonlinear contrast imaging using microbubble- based contrast agents has been widely investigated. However, the degree of contrast enhancement is often limited by overlap between the spectra of the tissue and microbubble nonlinear responses, which makes it difficult to separate them. The use of ensemble empirical mode decomposition (EEMD) in the Hilbert-Huang transform (HHT) was previously explored with the aim

Shang-Ching Lin; Pai-Chi Li

2011-01-01

184

Fault diagnosis of rotating machinery using an improved HHT based on EEMD and sensitive IMFs  

Microsoft Academic Search

A Hilbert-Huang transform (HHT) is a time-frequency technique and has been widely applied to analyzing vibration signals in the field of fault diagnosis of rotating machinery. It analyzes the vibration signals using intrinsic mode functions (IMFs) extracted using empirical mode decomposition (EMD). However, EMD sometimes cannot reveal the signal characteristics accurately because of the problem of mode mixing. Ensemble empirical

Yaguo Lei; Ming J. Zuo

2009-01-01

185

Massively Parallel Neural Signal Processing on a Many-Core Platform  

Microsoft Academic Search

Although the ensemble empirical mode decomposition (EEMD) method and Hilbert-Huang transform (HHT) offer an unrivaled opportunity to understand neural signals, the EEMD algorithm’s complexity and neural signals’ massive size have hampered EEMD application. However, a new approach using a many-core platform has proven both efficient and effective for massively parallel neural signal processing.

Dan Chen; Lizhe Wang; Gaoxiang Ouyang; Xiaoli Li

2011-01-01

186

American Council on Consumer Interests Annual Conference (35th, Baltimore, Maryland, March 29-April 1, 1989). The Proceedings.  

ERIC Educational Resources Information Center

Among the 90 papers in this volume, education-related titles are as follows: "The Colston Warne Legacy" (Peterson); "Keeping a File on Survey Respondents" (Huang); "Aging-in-Place: Are Responses in the Best Interest of Elderly Consumers?" (Stum); "Low-Income Elderly in Health Maintenance Organizations: Enrollment, Satisfaction, & Understanding"…

Carsky, Mary L., Ed.

187

A new approach to the existence of equilibria in vector lattices  

Microsoft Academic Search

Motivated by recent work of Huang and Kreps it is shown that the existence of a general equilibrium in an exchange economy whose commodity space is a vector lattice is guaranteed if (in addition to standard hypotheses) the price space is also a lattice. This is very weak in contrast with the usual requirement that the topology of the commodity

Andreu Mas-Colell; Scott F. Richard

1991-01-01

188

A finite-dimensional quantum model for the stock market  

Microsoft Academic Search

We present a finite-dimensional version of the quantum model for the stock market proposed in [C. Zhang and L. Huang, A quantum model for the stock market, Physica A 389(2010) 5769]. Our approach is an attempt to make this model consistent with the discrete nature of the stock price and is based on the mathematical formalism used in the case

Liviu-Adrian Cotfas

2012-01-01

189

Plant Growth Regulator and Mowing Height Effects on Seasonal Root Growth of Penncross Creeping Bentgrass  

Microsoft Academic Search

atures and poor soil aeration reduces root growth and root viability in creeping bentgrass, and contributes to Summer decline of creeping bentgrass (Agrostis palustris Huds. summer bentgrass decline (Huang et al., 1998a,b). (Agrostis stolonifera var. palustris (Huds.) Farw.) root growth is Strategies to reduce creeping bentgrass summer root an annual concern in many regions of the USA. A 2-yr field

Matthew J. Fagerness; Fred H. Yelverton

2001-01-01

190

Development of methods for the field evaluation of Oobius agrili (Hymenoptera: Encyrtidae) in North America, a newly introduced egg parasitoid of the emerald ash borer (Coleoptera: Buprestidae)  

Technology Transfer Automated Retrieval System (TEKTRAN)

A field study was conducted in forested plots near Lansing, Michigan in 2008 and 2009 to evaluate the newly introduced egg parasitoid, Oobius agrili Zhang and Huang (Hymenoptera: Encyrtidae), for control of the invasive emerald ash borer (EAB), Agrilus planipennis Fairmaire (Coleoptera: Buprestidae)...

191

Development of methods for the field evaluation of Oobius agrili (Hymenoptera: Encyrtidae) in North America, a newly introduced egg parasitoid of the emerald ash borer (Coleoptera: Buprestidae)  

Microsoft Academic Search

A field study was conducted in forested plots near Lansing, Michigan in 2008 and 2009 to evaluate the newly introduced egg parasitoid Oobius agrili Zhang and Huang (Hymenoptera: Encyrtidae) for control of the invasive emerald ash borer (EAB), Agrilus planipennis Fairmaire (Coleoptera: Buprestidae). To measure parasitism by O. agrili, laboratory-reared “sentinel EAB eggs” were deployed under bark flaps on trunks

Jian J. Duan; Leah S. Bauer; Michael D. Ulyshen; Juli R. Gould; Roy Van Driesche

2011-01-01

192

Deja Vu All over Again: Re-Revisiting the Conceptual Status of Early Word Learning: Comment on Smith and Samuelson (2006)  

ERIC Educational Resources Information Center

|The authors assert that L. B. Smith and L. Samuelson's (2006; see record EJ750228) most recent critique of A. E. Booth, S. R. Waxman, and Y. T. Huang's (2005; see record EJ684979) work missed its mark, deflecting attention from the important theoretical difference between the two sets of authors' positions and focusing instead on imagined…

Booth, Amy E.; Waxman, Sandra R.

2006-01-01

193

Explanation of the superconducting suspension effect  

SciTech Connect

Stable suspension of a superconducting sample below a magnet was recently reported by Peters et al. (Appl. Phys. Lett. 52, 2066 (1988)) and Huang et al. (Mod. Phys. Lett. B 2, 869 (1988)). The suspension effect and its vertical stability are demonstrated by a thought experiment.

Sezginer, A.

1989-05-01

194

A fuzzy multiobjective fractional goal programming approach to portfolio selection problem  

Microsoft Academic Search

Portfolio selection is concerned with selecting a combination of securities among portfolios containing large numbers of securities to reach the goal of obtaining satisfactory investment return (Huang 2006). It is difficult to decide which securities should be selected because of the uncertainty on their returns. Modern portfolio theory started from Markowitz(1952)'s main research work. Tanaka and Guo(1999) formulated portfolio selection

Nimet YAPICI

195

Author Affiliation Index: A New Approach to Marketing Journal Ranking  

ERIC Educational Resources Information Center

|Previous research has adopted various methods to assess the relative quality of academic marketing journals. This study, as a replication and extension of Chen and Huang (2007), introduces the Author Affiliation Index (AAI) as an alternative approach to assessing marketing journal quality. The AAI is defined as the ratio of articles authored by…

Pan, Yue; Chen, Carl R.

2011-01-01

196

ARE WE REALLY MAKING A DIFFERENCE? The gap between outcomes and evaluation research in public relations campaigns  

Microsoft Academic Search

Public relations helps organisations establish reputations (Plowman, Briggs & Huang 2001), improve community relationships (Ledingham & Bruning 2000, Stark & Kruckeberg 2001), resolve conflict (Coombs 2001, Ehling, White & Grunig 1992, Grunig 2001, Springston & Keyton 2001), and change attitudes and behaviours (Cutlip, Center & Broom 2000), Grunig & Repper 1992, Hendrix 2004). Such outcomes are valued by managers (Guth

Robina Xavier; Australia Amisha Patel; Australia Kim Johnston

2004-01-01

197

Modern Foreign Languages: A Refereed International Journal of Linguistics and Applied Linguistics, 2001.  

ERIC Educational Resources Information Center

|These three issues contain the following articles written in Chinese: "On Conflated Theme in Systemic Functional Grammar" (Huang Guo-Wen); "A Cognitive Approach to the Conceptual Semantic Structures of Causation" (Cheng Qi-Long); "Falsifying the Internal Argument Hypothesis" (Zhao Yan-Chun); "Existential Sentences in English and Chinese: Towards…

Ying, Du, Ed; Zidong, Huang, Ed.

2001-01-01

198

Impacts of recent cultivation on genetic diversity pattern of a medicinal plant, Scutellaria baicalensis (Lamiaceae)  

Microsoft Academic Search

BACKGROUND: Cultivation of medicinal plants is not only a means for meeting current and future demands for large volume production of plant-based drug and herbal remedies, but also a means of relieving harvest pressure on wild populations. Scutellaria baicalensis Georgi (Huang-qin or Chinese skullcap) is a very important medicinal plant in China. Over the past several decades, wild resource of

Qing-Jun Yuan; Zhi-Yong Zhang; Juan Hu; Lan-Ping Guo; Ai-Juan Shao; Lu-Qi Huang

2010-01-01

199

76 FR 31616 - Government-Owned Inventions; Availability for Licensing  

Federal Register 2010, 2011, 2012, 2013

...Tiukinhoy-Laing SD, Huang S, Klegerman M, Holland CK, McPherson DD. Ultrasound-facilitated thrombolysis using tissue-plasminogen activator-loaded...Oberoi J, Stone MJ, et al. Pulsed-high intensity focused ultrasound enhances thrombolysis in an in vitro model. Radiology...

2011-06-01

200

Empirical mode decomposition as a filter bank  

Microsoft Academic Search

Empirical mode decomposition (EMD) has recently been pioneered by Huang et al. for adaptively representing nonstationary signals as sums of zero-mean amplitude modulation frequency modulation components. In order to better understand the way EMD behaves in stochastic situations involving broadband noise, we report here on numerical experiments based on fractional Gaussian noise. In such a case, it turns out that

Patrick Flandrin; Gabriel Rilling; Paulo Goncalves

2004-01-01

201

Herd Behavior in Latin American Stock Markets  

Microsoft Academic Search

This article investigates the presence of herd behavior in Latin American stock markets using the methodologies proposed by Christie and Huang (1995) and Chang, Cheng, and Khorana (2000). Daily closing prices and trading volumes from January 3, 2000 to September 15, 2010 from the stock markets of Argentina, Brazil, Chile, Mexico, and the United States were analyzed. The US market

Rafael Porto de Almeida; Hudson Chaves Costa; Newton C. A. da Costa Jr

2012-01-01

202

Receptor-mediated actions of renin and prorenin  

Microsoft Academic Search

Renin can induce renal disease by generating angiotensin II and, thereby, increasing fibrosis. Huang et al describe a new mechanism of action whereby the renin–angiotensin system can also exert this effect. Direct activation of the renin\\/prorenin receptor in mesangial cells induced synthesis of TGF-? and profibrotic proteins. Hence, like other proteases such as thrombin, renin and prorenin are capable of

J A Oliver; Juan Oliver

2006-01-01

203

Ooencyrtus marcelloi sp. nov. (Hymenoptera: Encyrtidae), an egg parasitoid of Heliconiini (Lepidoptera: Nymphalidae: Heliconiinae) on passion vines (Malpighiales: Passifloraceae) in Central America  

Microsoft Academic Search

A new species belonging to the genus Ooencyrtus Ashmead is described. Ooencyrtus marcelloi sp. nov. has been reared from eggs of Heliconiini (Lepidoptera: Nymphalidae, Heliconiinae) collected in Panama on Passiflora spp. The new species is compared with its closest Ooencyrtus species, i.e. O. caligo Noyes, O. neustriae Mercet, O. flavipes (Timberlake), O. camerounensis (Risbec), O. endymion Huang and Noyes and

Emilio Guerrieri; Martinus E. Huigens; Catalina Estrada; Jozef B. Woelke; Marjolein de Rijk; Nina E. Fatouros; Annette Aiello; John S. Noyes

2009-01-01

204

Ooencyrtus marcelloi sp. nov. (Hymenoptera: Encyrtidae), an egg parasitoid of Heliconiini (Lepidoptera: Nymphalidae: Heliconiinae) on passion vines (Malpighiales: Passifloraceae) in Central America  

Microsoft Academic Search

A new species belonging to the genus Ooencyrtus Ashmead is described. Ooencyrtus marcelloi sp. nov. has been reared from eggs of Heliconiini (Lepidoptera: Nymphalidae, Heliconiinae) collected in Panama on Passiflora spp. The new species is compared with its closest Ooencyrtus species, i.e. O. caligo Noyes, O. neustriae Mercet, O. flavipes (Timberlake), O. camerounensis (Risbec), O. endymion Huang and Noyes and

E. Guerrieri; M. E. Huigens; C. Estrada; J. B. Woelke; Rijk de M; N. E. Fatouros; A. Aiello; J. S. Noyes

2010-01-01

205

Author Affiliation Index: A New Approach to Marketing Journal Ranking  

ERIC Educational Resources Information Center

Previous research has adopted various methods to assess the relative quality of academic marketing journals. This study, as a replication and extension of Chen and Huang (2007), introduces the Author Affiliation Index (AAI) as an alternative approach to assessing marketing journal quality. The AAI is defined as the ratio of articles authored by…

Pan, Yue; Chen, Carl R.

2011-01-01

206

Target fluctuation models for radar system design and performance analysis: an overview of three papers  

Microsoft Academic Search

The author discusses the value of the now-released Swerling (1996) paper (ibid., pp. 698-709) in which chi-square target models replace the now-obsolete Swerling models and the merits of the papers by Xu & Huang (ibid., pp. 710-14) and Johnston (ibid., pp. 715-20).

STEPHEN L. JOHNSTON

1997-01-01

207

A Comparative Study of Canadian and Taiwanese Grade 5 Children's Environmental Behaviors, Attitudes, Concerns, Emotional Dispositions, and Knowledge.  

ERIC Educational Resources Information Center

|This study explored the cultural influences on children's self-reported environmental actions, perceptions, and understandings; investigated the relationships among the behavioral, affective, cognitive, and demographic variables; and developed models of children's responsible environmental behavior (Huang, 2001). The cross-cultural comparison…

Huang, Hsin-Ping; Yore, Larry D.

208

Climate change inferred from borehole temperatures: minimal  

Microsoft Academic Search

Borehole temperature-depth profiles contain information about surface ground temperature histories over time scales of several centuries and in particular prior to the widespread availability of surface air temperature records [Huang et al, Nature, 2000; Harris and Chapman, GRL, 2001]. Borehole-based reconstructions on the regional and hemispheric scale yield significantly different magnitudes of warming in the past 500 years when compared

M. G. Bartlett; R. N. Harris; D. S. Chapman

2004-01-01

209

Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (81st, Baltimore, Maryland, August 5-8, 1998). Visual Communication.  

ERIC Educational Resources Information Center

|The Visual Communication section of the Proceedings contains the following 12 papers: "The Limits of Copyright Protection for the Use of Visual Works in Motion Pictures, Print Media, and Pop Art in the 1990s" (Andy Bechtel and Arati Korwar); "Afterthoughts on the Representational Strategies of the FSA Documentary" (Edgar Shaohua Huang); "Design…

Association for Education in Journalism and Mass Communication.

210

EFFECTS OF METAL COMPONENTS IN CONCENTRATED AMBIENT AIR PARTICLES ON PULMONARY INJURY  

EPA Science Inventory

EFFECTS OF METAL COMPONENTS IN CONCENTRATED AMBIENT AIR PARTICLES ON PULMONARY INJURY. Yuh-Chin Huang, Jackie Stonehuerner, Jackie Carter, Andrew J. Ghio, Robert B. Devlin. NHEERL, US EPA, RTP, NC. The mechanisms for cardiopulmonary morbidity associated with exposure to air po...

211

Influence On The Physical Universe By Wormhole Generated Extra Dimensional space  

Microsoft Academic Search

We use the Gu-Huang model for a special case when the universe is seven dimensional. In the core of extra dimension we place a modified Gidding-Strominger wormhole. This wormhole is separated by a thin wall from the extra dimensional space. The wormhole content is assumed to satisfy the adiabatic gas law. The wormhole pressure penetrates into the extra dimension. We

A. L. Choudhury

2003-01-01

212

Nonlocal mode mixing and surface-plasmon-polariton-mediated enhancement of diffracted terahertz fields by a conductive grating  

Microsoft Academic Search

This work generalizes our previous study of the effect of plasma-wave induced longitudinal fields [D. H. Huang J. Appl. Phys. 100, 113711 (2006)]. We incorporate a conductive grating on top of a conducting sheet for generating and mixing Bragg modes arising from a reflected and\\/or transmitted electromagnetic field. It also generalizes our recent work on the coupling of electronically modulated

Danhong Huang; Godfrey Gumbs; P. M. Alsing; D. A. Cardimona

2008-01-01

213

CONTRIBUTION OF INSPIRATORY FLOW TO ACTIVATION OF EGFR, RAS, MAPK, ATF-2 AND C-JUN DURING LUNG STRETCH  

EPA Science Inventory

Contribution of Inspiratory Flow to Activation of EGFR, Ras, MAPK, ATF-2 and c-Jun during Lung Stretch R. Silbajoris 1, Z. Li 2, J. M. Samet 1 and Y. C. Huang 1. 1 NHEERL, ORD, US EPA, RTP, NC and 2 CEMALB, UNC-CH, Chapel Hill, NC . Mechanical ventilation with larg...

214

Identity, Stress, and Resilience in Lesbians, Gay Men, and Bisexuals of Color  

ERIC Educational Resources Information Center

The author addresses two issues raised in Moradi, DeBlaere, and Huang's Major Contribution to this issue: the intersection of racial/ethnic and lesbian, gay, and bisexual (LGB) identities and the question of stress and resilience. The author expands on Moradi et al.'s work, hoping to encourage further research. On the intersection of identities,…

Meyer, Ilan H.

2010-01-01

215

A Fast IP Routing Lookup Scheme  

Microsoft Academic Search

Abstract—A major issue in router design for the next genera- tion Internet is the fast IP address lookup mechanism. The existing scheme by Huang et al. performs the IP address lookup in hard- ware in which the forwarding table can be compressed to fit into reasonable-size SRAM, and a lookup can be accomplished in three memory accesses. In this letter,

Pi-chung Wang; Yaw-chung Chen; Chia-tai Chan

2000-01-01

216

Pulsars as spiral arm tracers  

Microsoft Academic Search

Pulsars are used to trace the spiral arms of the Galaxy. Present pulsar characteristics are used to divide them into two pulsar types as defined by Huang (1987). The ages of Type II pulsars and the galactic rotation curve are used to determine their position at birth. The spiral arm pattern velocity is used to reconstruct the arms from which

Siobahn Morgan

1990-01-01

217

Structure from motion-a critical analysis of methods  

Microsoft Academic Search

Existing methods for structure from motion are classified and analyzed and mathematical relationships among them are shown. Their behavior on the same synthetic data is evaluated, examining the effect of noise, initial estimates, and the amount of motion. The missing necessary polynomial constraint on the singular values of R.Y. Tsai and T.S. Huang's (1981) essential parameter matrix is shown, and

Charles P. Jerian; Ramesh Jain

1991-01-01

218

MODULATION OF HYPOXIC PULMONARY VASOCONSTRICTION BY ERYTHROCYTIC NITRIC OXIDE  

EPA Science Inventory

Abstract American Heart Association 2001 Modulation of Hypoxic Pulmonary Vasoconstriction by Erythrocytic NO McMahon TJ1, Gow AJ1, Huang YCT4, Stamler JS1,2,3 Departments of Medicine1 and Biochemistry2, and Howard Hughes Medical Institute3, Duke University Med...

219

Interactive Vocabulary Acquisition in XTRA  

Microsoft Academic Search

This paper describes a practical solution to on- line dictionary update in XTRA, a machine transla- tion system developed by Xiuming Huang at the Computing Research Laboratory of New Mexico State University. The focus of the discussion in on IVES — an Interactive Vocabulary Enrichment Sys­ tem built by this writer for XTRA, It reflects an on­ going effort at

Cheng-ming Guo

1987-01-01

220

Substance Abuse Treatment Admissions Aged 15 to 17  

MedlinePLUS

... R., Hazen, A. L., & Hough, R. L. (1999). Adolescent alcohol and drug abuse and health. Journal of Adolescent Health, 24 (6), 412-421. 4 Huang, D. ... brochure.pdf ); and (3) a resource to address drug use among teens if you are not the parent or ... Abuse and Mental Health Services Administration, Center for Behavioral ...

221

Cultural Value Similarities and Differences Among Asian American Ethnic Groups  

Microsoft Academic Search

Using data on 570 Chinese, Filipino, Korean, and Japanese American college students from 3 previous studies (1 published [B. S. K. Kim, D. R. Atkinson, & P. H. Yang, 1999] and 2 unpublished [B. S. K. Kim, 1999; E. C. Wong, B. S. K. Kim, N. W. S. Zane, I. J. Kim, & J. S. Huang, 1999]), the authors subjected

Bryan S. K. Kim; Peggy H. Yang; Donald R. Atkinson; Maren M. Wolfe; Sehee Hong

2001-01-01

222

Voxelization in Common Sampling Lattices  

Microsoft Academic Search

In this paper we introduce algorithms to voxelize polyg- onal meshes in common sampling lattices. In the case of Cartesian lattices, we complete the separability and minimality proof for the voxelization method presented by Huang et al (5). We extend the ideas to general 2D lat- tices, including hexagonal lattices, and 3D body-centred cubic lattices. The notion of connectedness in

Haris Widjaya; Torsten Möller; Alireza Entezari

2003-01-01

223

The activation of a single fault as a reduced self-affine image of the whole regional seismicity and a magnified self-affine image of the laboratory seismicity in terms of kHz electromagnetic precursors  

Microsoft Academic Search

Huang and Turcotte [1] have pointed out that the statistics of regional seismicity could be merely a macroscopic reflection of the physical processes in earthquake (EQ) source. Herein, we check this hypothesis in terms of precursory kHz electromagnetic (EM) emissions possibly associated with the fracture of high strength and large asperities that are distributed along the activated single fault sustaining

C. Papadimitriou; M. Kalimeri; J. Kopanas; G. Antonopoulos; A. Peratzakis; K. Eftaxias

2009-01-01

224

Separation and Determination of Ephedrine Enantiomers and Synephrine by High Performance Capillary Electrophoresis in Dietary Supplements  

Microsoft Academic Search

The chiral separation of ephedrine alkaloids by high performance capillary electrophoresis is of great interest since the enantiomers exhibit quantitative and qualitative differences in pharmacological activity. The isomers of (-)-ephedrine, (+)-pseudoephedrine, (-)- N-methylephedrine, (+)- N-methylpseudoephedrine, (+)-norpseudoephedrine and (-)-norephedrine are the major bioactive components of E. sinica (Ma-Huang) which is a Chinese herb used for weight loss and as an energy

B. Avula; I. A. Khan

2004-01-01

225

Gaining Insight to Transfer of Training through the Lens of Social Psychology  

ERIC Educational Resources Information Center

|The article deals with the question under which conditions people change their behavior through vocational trainings or not. Following the demand of more theory-driven investigations in transfer research (Blume, Ford, Baldwin, & Huang, 2010) we wish to add the perspective of social psychology. We therefore illustrate how well-known concepts from…

Weisweiler, Silke; Nikitopoulos, Alexandra; Netzel, Janine; Frey, Dieter

2013-01-01

226

The complete proof on the optimal ordering policy under cash discount and trade credit  

Microsoft Academic Search

Huang ((2005), ‘Buyer's Optimal Ordering Policy and Payment Policy under Supplier Credit’, International Journal of Systems Science, 36, 801–807) investigates the buyer's optimal ordering policy and payment policy under supplier credit. His inventory model is correct and interesting. Basically, he uses an algebraic method to locate the optimal solution of the annual total relevant cost TRC(T) and ignores the role

Kun-Jen Chung

2010-01-01

227

Interlending Section. Collections and Services Division. Papers.  

ERIC Educational Resources Information Center

|Papers on interlibrary lending which were presented at the 1982 International Federation of Library Associations (IFLA) conference include: (1) "Inter-Library Loan Service of the National Library of China," a description by Huang Jungui and Zhao Qikang (People's Republic of China) of the history, organization, purposes, and possible future…

International Federation of Library Associations, The Hague (Netherlands).

228

A theory of tensor products for vertex operator algebra satsifying C_2-cofiniteness  

Microsoft Academic Search

We reformed the tensor product theory of vertex operator algebras developed by Huang and Lepowsky so that we could apply it to all vertex operator algebras satisfying C_2-cofiniteness. We also showed that the tensor product theory develops naturally if we include not only ordinary modules, but also weak modules with a composition series of finite length (we call it an

Masahiko Miyamoto

2003-01-01

229

An Integrated Decision Model for Evaluating Educational Web Sites from the Fuzzy Subjective and Objective Perspectives  

ERIC Educational Resources Information Center

|With advances in information and network technologies, lots of data have been digitized to reveal information for users by the construction of Web sites. Unfortunately, they are both overloading and overlapping in Internet so that users cannot distinguish their quality. To address this issue in education, Hwang, Huang, and Tseng proposed a group…

Huang, Tony Cheng-Kui; Huang, Chih-Hong

2010-01-01

230

Pharmacology of ephedra alkaloids and caffeine after single-dose dietary supplement use  

Microsoft Academic Search

Objective: Serious cardiovascular toxicity has been reported in people taking dietary supplements that contain ma huang (Ephedra) and guarana (caffeine). We assessed the pharmacokinetics and pharmacodynamics of a dietary supplement that contains these herbal stimulants.Methods: Eight healthy adults received a single oral dose of a thermogenic dietary supplement labeled to contain 20 mg ephedrine alkaloids and 200 mg caffeine after

Christine A. Haller; Peyton Jacob; Neal L. Benowitz

2002-01-01

231

American Council on Consumer Interests Annual Conference (35th, Baltimore, Maryland, March 29-April 1, 1989). The Proceedings.  

ERIC Educational Resources Information Center

|Among the 90 papers in this volume, education-related titles are as follows: "The Colston Warne Legacy" (Peterson); "Keeping a File on Survey Respondents" (Huang); "Aging-in-Place: Are Responses in the Best Interest of Elderly Consumers?" (Stum); "Low-Income Elderly in Health Maintenance Organizations: Enrollment, Satisfaction, & Understanding"…

Carsky, Mary L., Ed.

232

Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (86th, Kansas City, Missouri, July 30-August 2, 2003). Communication Technology and Policy Division.  

ERIC Educational Resources Information Center

|The Communication Technology and Policy Division of the proceedings contains the following 15 papers: "Both Sides of the Digital Divide in Appalachia: Uses and Perceived Benefits of Internet Access" (Daniel Riffe); "Bridging Newsrooms and Classrooms: Preparing the Next Generation of Journalists for Converged Media" (Edgar Huang, Karen Davison,…

2003

233

Provenance and weathering control on river bed sediments of the eastern Tibetan Plateau and the Russian Far East  

Microsoft Academic Search

We investigated the petrography and major, trace and rare earth element compositions of the bed sediments from the large rivers draining the eastern Tibetan Plateau (ETP) — the Huang He (Yellow), Chang Jiang (Yangtze), Hong He (Red), Mekong and Salween. The combined drainage spans tropical, temperate and arid climate zones. In addition, samples from the Lena River, draining the Verkhoyansk

Joniell B. Borges; Youngsook Huh; Seulgi Moon; Hyeonjeong Noh

2008-01-01

234

Commissioning the NOAO Data Management System  

Microsoft Academic Search

The NOAO Data Management System (Barg et al. 2007) is comprised of several large subsystems. Its Data Transport System (Huang et al. 2007) annually conveys Tbytes of data between six remote, intercontinental sites. The NOAO Science Archive (NSA) has been safeguarding key NOAO data products for almost five years. NSA release 3.0 will dramatically increase the data holdings as well

H. H. Lanning; R. Seaman; R. C. Smith

2007-01-01

235

Ballooning instability at the plasma sheet–lobe interface and its implications for polar arc formation  

Microsoft Academic Search

Huang et al. (1987, 1989) reported hot filaments of plasma sheet origin filling the magnetospheric lobes during northward interplanetary magnetic field (IMF). On the other hand, cold plasma transients of presumably lobe origin are often observed in the plasma sheet. These features can be interpreted in terms of plasma exchange at the plasma sheet–lobe interface (PSLI) proceeding in a filamentary

I. V. Golovchanskaya; A. Kullen; Y. P. Maltsev; H. Biernat

2006-01-01

236

Ballooning instability at the plasma sheet-lobe interface and its implications for polar arc formation  

Microsoft Academic Search

Huang et al. (1987, 1989) reported hot filaments of plasma sheet origin filling the magnetospheric lobes during northward interplanetary magnetic field (IMF). On the other hand, cold plasma transients of presumably lobe origin are often observed in the plasma sheet. These features can be interpreted in terms of plasma exchange at the plasma sheet-lobe interface (PSLI) proceeding in a filamentary

I. V. Golovchanskaya; A. Kullen; Y. P. Maltsev; H. Biernat

2006-01-01

237

The Schizosaccharomyces pombe fusion gene hal3 encodes three distinct activities.  

PubMed

Saccharomyces cerevisiae?Hal3 and Vhs3 are moonlighting proteins, forming an atypical heterotrimeric decarboxylase (PPCDC) required for CoA biosynthesis, and regulating cation homeostasis by inhibition of the Ppz1 phosphatase. The Schizosaccharomyces pombe?ORF SPAC15E1.04 (renamed as Sp?hal3) encodes a protein whose amino-terminal half is similar to Sc Hal3 whereas its carboxyl-terminal half is related to thymidylate synthase (TS). We show that Sp?Hal3 and/or its N-terminal domain retain the ability to bind to and modestly inhibit in vitro S.?cerevisiae?Ppz1 as well as its S.?pombe homolog Pzh1, and also exhibit PPCDC activity in vitro and provide PPCDC function in vivo, indicating that Sp?Hal3 is a monogenic PPCDC in fission yeast. Whereas the Sp Hal3 N-terminal domain partially mimics Sc Hal3 functions, the entire protein and its carboxyl-terminal domain rescue the S.?cerevisiae?cdc21 mutant, thus proving TS function. Additionally, we show that the 70?kDa Sp Hal3 protein is not proteolytically processed under diverse forms of stress and that, as predicted, Sp?hal3 is an essential gene. Therefore, Sp?hal3 represents a fusion event that joined three different functional activities in the same gene. The possible advantage derived from this surprising combination of essential proteins is discussed. PMID:23962284

Molero, Cristina; Petrényi, Katalin; González, Asier; Carmona, Mercè; Gelis, Samuel; Abrie, J Albert; Strauss, Erick; Ramos, José; Dombradi, Viktor; Hidalgo, Elena; Ariño, Joaquín

2013-09-10

238

Removal of cyclobutane pyrimidine dimers from a UV-irradiated shuttle vector introduced into human cells  

SciTech Connect

A shuttle vector (pZH-1) carrying the E. Coli lacZ gene under control of the SV40 early promoter was irradiated with UV and introduced into repair-proficient or repair-deficient human cell lines. The expression of irradiated lacZ compared to unirradiated lacZ was greater in repair-proficient cells (HT-1080) than in repair-deficient cells (XP12RO-SV40) belonging to xeroderma pigmentosum complementation group A. To ascertain whether the expression of lacZ in the repair-proficient cells was correlated with the removal of cyclobutane pyrimidine dimers (CPDs), the authors purified DNA from the recipient cells and used the CPD-specific enzyme T4 endonuclease V to measure the frequency of CPDs remaining in the plasmid as a whole and in two restriction fragments derived from it. They found that removal of CPDs occurred in both fragments in the repair-proficient cells but not in the repair-deficient cells. The results provide the first direct evidence for the removal of CPDs from UV irradiated plasmids introduced into human cells and support the notion that expression of the UV-damaged lacZ gene in repair-proficient human cells reflects the removal of transcription blocking lesions from the gene.

Ganesan, A.K.; Hanawalt, P.C. (Stanford Univ., CA (United States))

1994-05-01

239

Genotoxicity and reproductive toxicity of bisphenol A and X-ray/bisphenol A combination in male mice.  

PubMed

This study was designed to investigate the effects of 2 weeks of exposure of male mice to bisphenol A (BPA) alone or in a combination with X-rays on the sperm count and quality as well as induction of DNA strand breaks in somatic and germ cells. Pzh:SFIS male mice were exposed to X-rays (0.05 and 0.10 Gy) or BPA (5, 10, 20, and 40 mg/kg) or to a combination of both (0.05 Gy + 5 mg/kg body weight of BPA and 0.10 Gy + 10 mg/kg of BPA). Both X-rays and BPA administered alone decreased sperm count and quality. X-rays induced DNA strand breaks in spleen cells, whereas BPA induced DNA strand breaks in lymphocytes and in cells from spleen, kidneys, and lung and in germ cells. After combined exposure to both agents, sperm count and quality were similar as after exposure to each agent alone and significantly reduced, compared to control. Levels of DNA damage in somatic and germ cells after combined exposure to lower, as well as higher, doses were significantly reduced, compared to the effects of BPA alone. Results confirmed the mutagenic ability of BPA. Combined exposure to X-rays and BPA leads to the prevention of DNA damage in somatic and germ cells of mice. PMID:22263531

Dobrzy?ska, Ma?gorzata M; Radzikowska, Joanna

2012-01-21

240

Decontamination of chemical and biological warfare (CBW) agents using an atmospheric pressure plasma jet (APPJ)  

SciTech Connect

The atmospheric pressure plasma jet (APPJ) [A. Sch{umlt u}tze {ital et al.}, IEEE Trans. Plasma Sci. {bold 26}, 1685 (1998)] is a nonthermal, high pressure, uniform glow plasma discharge that produces a high velocity effluent stream of highly reactive chemical species. The discharge operates on a feedstock gas (e.g., He/O{sub 2}/H{sub 2}O), which flows between an outer, grounded, cylindrical electrode and an inner, coaxial electrode powered at 13.56 MHz rf. While passing through the plasma, the feedgas becomes excited, dissociated or ionized by electron impact. Once the gas exits the discharge volume, ions and electrons are rapidly lost by recombination, but the fast-flowing effluent still contains neutral metastable species (e.g., O{sub 2}{sup {asterisk}}, He{sup {asterisk}}) and radicals (e.g., O, OH). This reactive effluent has been shown to be an effective neutralizer of surrogates for anthrax spores and mustard blister agent. Unlike conventional wet decontamination methods, the plasma effluent does not cause corrosion and it does not destroy wiring, electronics, or most plastics, making it highly suitable for decontamination of sensitive equipment and interior spaces. Furthermore, the reactive species in the effluent rapidly degrade into harmless products leaving no lingering residue or harmful by-products. {copyright} {ital 1999 American Institute of Physics.}

Herrmann, H.W.; Henins, I.; Park, J.; Selwyn, G.S. [Physics Division, Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States)

1999-05-01

241

Delocalized Davydov D1 Ansatz for the Holstein polaron.  

PubMed

An efficient, yet very accurate trial wave function, constructed from projecting the well-known Davydov D1 Ansatz onto momentum eigenstates, is employed to study the ground state properties of the generalized Holstein Hamiltonian with simultaneous diagonal and off-diagonal coupling. Ground-state energies have been obtained with a precision matching that of the computationally much more demanding density-matrix renormalization group method. The delocalized D1 Ansatz lowers the ground-state energies at the Brillouin zone boundary significantly compared with the Toyozawa and Global-Local Ansa?tze in the weak coupling regime, while considerable improvement is demonstrated to have been achieved over the entire Brillouin zone in the strong coupling regime. Unique solutions are obtained with the delocalized D1 for different initial conditions when the transfer integral is 20 times the phonon frequency at the zone center, implying the absence of any self-trapping discontinuity. The scaled correlation variance is found to fit satisfactorily well with the predictions of the perturbation theories. PMID:23656123

Sun, Jin; Duan, Liwei; Zhao, Yang

2013-05-01

242

Generalization of the Hartree-Fock approach to collision processes  

SciTech Connect

The conventional Hartree and Hartree-Fock approaches for bound states are generalized to treat atomic collision processes. All the single-particle orbitals, for both bound and scattering states, are determined simultaneously by requiring full self-consistency. This generalization is achieved by introducing two {ital Ans{umlt a}tze}: (a) the weak asymptotic boundary condition, which maintains the correct scattering energy and target orbitals with correct number of nodes, and (b) square integrable amputated scattering functions to generate self-consistent field (SCF) potentials for the target orbitals. The exact initial target and final-state asymptotic wave functions are not required and thus need not be specified {ital a priori}, as they are determined simultaneously by the SCF iterations. To check the asymptotic behavior of the solution, the theory is applied to elastic electron-hydrogen scattering at low energies. The solution is found to be stable and the weak asymptotic condition is sufficient to produce the correct scattering amplitudes. The SCF potential for the target orbital shows the strong penetration by the projectile electron during the collision, but the exchange term tends to restore the original form. Potential applicabilities of this extension are discussed, including the treatment of ionization and shake-off processes. {copyright} {ital 1997} {ital The American Physical Society}

Hahn, Y. [Department of Physics, University of Connecticut, Storrs, Connecticut 06269 (United States)]|[TRG, 49 Timber Drive, Storrs, Connecticut 06268 (United States)

1997-06-01

243

The Purpose-Like Nature of Life  

NASA Astrophysics Data System (ADS)

According to Jeffrey Tze-Fei Wong (2002): A living system is one capable of reproduction and evolution, with a fundamental logic that demands an incessant search for performance with respect to its building blocks and arrangement of these building blocks. The search will end only when perfection or near perfection is reached. Without this built-in search, living systems could not have achieved the level of complexity and excellence to deserve the designation of life." The reader must understand that a distinction exists between how the common language defines purpose and what the theory of early life means by it. In Dexter's dictionary the word purpose' is anthropocentrically associated to performing an action with a conscious (deliberate) aim, intention and/or design. Yet life displays elaborate and suitable features that resemble the results of a purpose-like action (Szathmáry 2002). In fact any material-energetic order has the potential for a tendency' (or purposefulness') directed in the opposite sense to entropy (Valenzuela 2002). Because the purposefulness' of their function is such a vigorous and typical property of living organisms (Korzeniewski 2001, Szathmáry 2002), the search for a theory of life is more productive if it focuses on the best explanation for life (Bedau 1998).

Radu, Popa

244

Chinese pipeline. 1; Automating hot-oil line first step in nationwide system  

SciTech Connect

This paper reports that design and installation of a pipeline automation system in China by Novacorp International Consulting Inc., Calgary, illustrates the experience of a North American company in that country. Automation of Shengli Oil Pipeline Co.'s 153 mile, 28 in. hot oil pipeline from Dongying to Huangdao (Dong-Huang) in Shandong Province, China, consisted of a dual redundant configuration, hot scada (supervisory control and data acquisition) system and a programmable logic controller (PLC) based station control for three pumping stations, one terminal station, and one meter station. During the final year of the project the Chinese Pipeline Bureau (PLB) commissioned a central scada system for all the pipelines in the country. The system center is located at the PLB headquarters in Langfang, Hebei near Beijing. The first link was to the Dong-Huang pipeline's scada system. The PLB has pipeline design personnel and was ultimately responsible for the pipeline design.

Blair, J.T. (Novacorp International Consulting Inc., Calgary (CA))

1992-08-31

245

Identification of the flavonoids in mungbean (Phaseolus radiatus L.) soup and their antioxidant activities.  

PubMed

Mung bean soup (MBS) has been traditionally taken as a kind of health food in China. To learn the mechanisms underlying its health benefits, antioxidant capacities of the soup prepared with three cultivars of mung bean were measured. The highest DPPH radical scavenging or ferric reducing activity was observed in soup of mung bean cv. Huang. The MBS of cv. Huang and Mao exhibited higher ABTS(+) reducing activities than MBS of cv. Ming. The two major flavonoids in the MBS were purified and identified as vitexin and isovitexin, respectively. Modeling samples containing vitexin and isovitexin at the same levels as them in the MBS were prepared to assess their antioxidant contributions in the MBS. Our results showed that antioxidant capacities of the MBS mainly derived from vitexin and isovitexin, these flavonoids accounted for the most of total DPPH radicals scavenging, ferric reducing and ABTS(+) reducing scavenging activities in MBS of all the three cultivars. PMID:22980894

Li, He; Cao, Dongdong; Yi, Jianyong; Cao, Jiankang; Jiang, Weibo

2012-07-17

246

Interactions between task repetition and psychosocial factors.  

PubMed

Psychosocial factors, individual factors, workplace requirements, and workplace organizational factors have all been reported as being associated with the risk of musculoskeletal disorders [11]. Huang, Feuerstein, and Sauter [5] described the various concepts and models proposed to link occupational stress and work-related upper extremity disorders, as well as the difficulty in verifying the suggested linkages. Huang et al. [5] suggested that decomposing a complex model would be an appropriate method to begin the investigations of the proposed models. Task repetition is a workplace requirement that is considered a potential risk factor for cumulative trauma and its relationship to psychosocial factors was investigated. The study found only weak to no statistically significant relationship between task repetition and reported psychosocial factors of job stress in workers in Taiwan. PMID:22317075

Riley, Michael W; Hung, Yu-Ting; Wang, Mao-Jiun; Lin, Yueh-Ling; Blunk, Jessica C

2012-01-01

247

Spectral representation theory of graded composite materials  

NASA Astrophysics Data System (ADS)

In graded composite materials, the physical properties can vary continuously in space and it may give different physical phenomena when compared with homogeneous materials. The Bergman-Milton spectral representation is a rigorous mathematical formalism to express the effective dielectric constant of nongraded composite materials [1]. In this study, we consider a material (rather than microsture [2]) graded composites, and generalize the Bergman-Milton spectral representation to extract the spectral density function for the effective dielectric constant of this graded composite material in the frequency domain [3]. Analytic and numerical solution will be presented for graded films and graded spheres. [1] D. J. Bergman, Phys. Rev. B 14, 4304 (1976). [2] J. P. Huang, K. W. Yu, G. Q. Gu, M. Karttunen, Phys. Rev. E 67, 051405 (2003). [3] L. Gao, J. P. Huang, K.W. Yu, Eur. Phys. J. B 36, 475 (2003).

Chan, K. L.; Kwok, C. M.; Yu, K. W.

2008-03-01

248

Myelin figures: an Elastic Instability?  

NASA Astrophysics Data System (ADS)

Myelin figures form when certain lamellar phase surfactants swell upon exposure to water. The formation of these myelins, which are tubular structures composed of multiple bilayers of surfactant, is puzzling because it represents the formation of a higher bending-energy configuration from a lower bending-energy initial state. We show that single myelins can be produced in isolation and require a driving force to form and grow; they retract into their parent structure when the driving is removed. We present a model, consistent with our experimental observations, where the formation of myelins is due to an elastic instability of the lamellar phase under internal stress. We propose an experiment to test of this model in comparison to other models, such as that of Huang et al.[1] [1]J.-R. Huang, L.-N. Zou, and T. A. Witten, Eur. Phys. J. E (2005). DOI: 10.1140/epje/e2005-00035-8.

Zou, Ling-Nan; Nagel, Sidney R.

2006-03-01

249

Use of Comparative Proteomics to Identify Key Proteins Related to Hepatic Lipid Metabolism in Broiler Chickens: Evidence Accounting for Differential Fat Deposition Between Strains  

Microsoft Academic Search

In order to investigate differences in fat metabolism during embryonic development, a comparative proteomics strategy was\\u000a employed using Arbor Acres (AA) and San Huang (SH) broiler chickens with different growth and fat deposition characteristics.\\u000a These birds were floor-reared and fed identical diets, and embryonic livers were collected from AA and SH chicken embryos\\u000a on days 9, 14 and 19 of

Jianzhen HuangXue; Xue Tang; Jiming Ruan; Haitian Ma; Sixiang Zou

2010-01-01

250

Bioactivities and sensory evaluation of Pu-erh teas made from three tea leaves in an improved pile fermentation process  

Microsoft Academic Search

Two commercial Pu-erh teas, 15-year-old Ta-Huang-In and 25-year-old Ta-Hon-In, were used for screening some species of fungi, yeasts, and bacteria, and six of them were isolated and identified as Actinoplanes aurantiacus, Actinoplanes pallidoaurantiacus, Actinoplanes purpeobrunneus, Streptomyces bacillaris, Streptomyces cavourensis subsp. cavourensis, and Streptomyces cinereus. They were selected for inoculated into thee tea leaves (Yun Nan from China, TTES-12 and C.

Yuh-Shuen Chen; Bing-Lan Liu; Yaw-Nan Chang

2010-01-01

251

On the Formation of Glass Microelectrodes  

Microsoft Academic Search

Glass microelectrodes are used widely in experimental studies of the electrophysiology of biological cells and their membranes. However, the pulling of these electrodes remains an art, based on trial-and-error. Following Huang et al. (2003), we derive a one-dimensional model for the stretching of a hollow glass tube that is being radiatively heated. Our framework allows us to consider two commonly

Huaxiong Huang; Jonathan J. Wylie; Robert M. Miura; Peter D. Howell

2007-01-01

252

A bio-molecular film ex-vivo model to evaluate the influence of canal dimensions and irrigation variables on the efficacy of irrigation  

Microsoft Academic Search

Huang T-Y, Gulabivala K, Ng Y-L. A bio-molecular film ex-vivo model to evaluate the influence of canal dimensions and irrigation variables on the efficacy of irrigation. Inter- national Endodontic Journal, 41, 60-71, 2008. Aims To devise an ex vivo model to test the efficacy of irrigation (static\\/dynamic) in removing a bio-molecular film from root canal walls. Methodology Fortyhumanteethwithsinglestraight canals were

T.-Y. Huang; K. Gulabivala; Y.-L. Ng

2007-01-01

253

Agent-based models of financial markets  

Microsoft Academic Search

This review deals with several microscopic ('agent-based') models of financial markets which have been studied by economists and physicists over the last decade: Kim-Markowitz, Levy-Levy-Solomon, Cont-Bouchaud, Solomon-Weisbuch, Lux-Marchesi, Donangelo-Sneppen and Solomon-Levy-Huang. After an overview of simulation approaches in financial economics, we first give a summary of the Donangelo-Sneppen model of monetary exchange and compare it with related models in economics

E. Samanidou; E. Zschischang; D. Stauffer; T. Lux

2007-01-01

254

Sliding Empirical Mode Decomposition for On-line Analysis of Biomedical Time Series  

Microsoft Academic Search

\\u000a Biomedical signals are in general non-linear and non-stationary. Empirical Mode Decomposition in conjunction with Hilbert-Huang Transform provides a fully adaptive and data-driven technique to extract Intrinsic Mode Functions (IMFs). The latter represent a complete set of orthogonal basis functions to represent non-linear and non-stationary time\\u000a series. Large scale biomedical time series necessitate an on-line analysis which is presented in this

A. Zeiler; R. Faltermeier; A. Tomé; C. Puntonet; A. Brawanski; E. Lang

255

Effect of theta burst stimulation on sensorimotor cortex in humans  

Microsoft Academic Search

Objective: To study the after-effect of theta burst transcranial magnetic stimulation (TBS) on sensorimotor cortex excitability as well as cortico-muscular synchronization in humans. Methods: We used a continuous TBS (cTBS) paradigm for 40 sec (600 pulses) (Huang et al., 2005). Somatosensory evoked potentials (SEPs) following electrical stimulation of right or left median nerve and motor evoked potentials (MEPs) in the

Kaoru Matsunaga; M. Saglam; N. Murayama; Y. Hayashida; R. Nakanishi

2009-01-01

256

Accent extraction of emotional speech based on modified ensemble empirical mode decomposition  

Microsoft Academic Search

Ensemble empirical mode decomposition (EEMD) is a noise-assisted adaptive data analysis method to solve the mode mixing problem caused by empirical mode decomposition (EMD), which is a significant step of Hilbert-Huang Transform (HHT). In this paper, a novel fast EEMD preferences algorithm called Quasi-Gradient Search (QGS) is proposed. For a given ensemble number, we first apply Nonlinear Correlation Coefficient (NCC)

Zhiyuan Shen; Qiang Wang; Yi Shen; Jing Jin; Yurong Lin

2010-01-01

257

Hard target penetration acceleration signals Time-frequency Analysis  

Microsoft Academic Search

The hard target penetration process is very complex and the various missile vibration signals are very rich. So Hard target penetration acceleration signals are non-stationary signals. We use the Hilbert-Huang transform (HHT) for Time­ frequency Analysis non-stationary signals in noisy environments. Empirical Mode Decomposition (EMD) is hard core of HHT so these maybes bring Mode Mixing. We put forward a

Huiyan Hao; Hui Zhao

2011-01-01

258

Pathological Voice Analysis and Classification Based on Empirical Mode Decomposition  

Microsoft Academic Search

\\u000a Empirical mode decomposition (EMD) is an algorithm for signal analysis recently introduced by Huang. It is a completely data-driven\\u000a non-linear method for the decomposition of a signal into AM - FM components. In this paper two new EMD-based methods for the\\u000a analysis and classification of pathological voices are presented. They are applied to speech signals corresponding to real\\u000a and simulated

Gastón Schlotthauer; María Eugenia Torres; Hugo Leonardo Rufiner

2009-01-01

259

Research on the EEMD algorithm of penetration acceleration signal processing based on independent component analysis  

Microsoft Academic Search

Penetration acceleration signal is a typical non-stationary signal, which cannot be effectively and accurately analyzed by traditional time-frequency analysis methods. EEMD algorithm improved based on the core algorithm EMD of Hilbert-Huang transform, effectively solved the mode aliasing problem of EMD algorithm and adaptive analyze the non-stationary random signals. However, EEMD algorithm also has some flaws, namely the IMF decomposed does

Xiao-feng Li; Ming-jie Liu; Shi-hu Wang

2010-01-01

260

Overexpression of G Protein-Coupled Receptor Kinase2 in Smooth Muscle Cells Reduces Neointimal Hyperplasia  

Microsoft Academic Search

K. Peppel, L. Zhang, T. T. T. Huynh, X. Huang, A. Jacobson, L. Brian, S. T. Exum, P.-O. Hagen and N. J. Freedman. Overexpression of G Protein-Coupled Receptor Kinase-2 in Smooth Muscle Cells Reduces Neointimal Hyperplasia. Journal of Molecular Cellular Cardiology (2002) 34, 1399–1409. The activation of vascular smooth muscle cells (SMCs) in neointimal hyperplasia involves signaling through receptor tyrosine

Karsten Peppel; Lisheng Zhang; Tam T. T. Huynh; Xuewei Huang; Anne Jacobson; Leigh Brian; Sabrina T. Exum; Per-Otto Hagen; Neil J. Freedman

2002-01-01

261

Effects of L-carnitine and Dietary Protein on Body Composition and Liver Lipid Content in Juvenile New GIFT Strain Nile Tilapia (Oreochromis niloticus)  

Microsoft Academic Search

Chen, G., Zhang, M., Zhang, J., Dong, H., Zhou, H., Tang, B., Huang, J., Shi, G., Jiang, L., Wu, Z. and Gu, B. 2010. Effects of L-carnitine and dietary protein on body composition and liver lipid content in juvenile new GIFT strain Nile tilapia (Oreochromis niloticus). J. Appl. Anim. Res., 37: 141–144.To assess the effects of different levels of dietary

Gang Chen; Minghui Zhang; Jiandong Zhang; Hongbiao Dong; Hui Zhou; Baogui Tang; Jiansheng Huang; Gang Shi; Ling Jiang; Zaohe Wu; Binhe Gu

2010-01-01

262

Tyrosyl phosphorylation toggles a Runx1 switch  

PubMed Central

The Runx1 transcription factor is post-translationally modified by seryl/threonyl phosphorylation, acetylation, and methylation that control its interactions with transcription factor partners and epigenetic coregulators. In this issue of Genes & Development, Huang and colleagues (pp. 1587–1601) describe how the regulation of Runx1 tyrosyl phosphorylation by Src family kinases and the Shp2 phosphatase toggle Runx1's interactions between different coregulatory molecules.

Neel, Benjamin G.; Speck, Nancy A.

2012-01-01

263

COMMITTEES: SQM2006 Organising and International Advisory Committees  

NASA Astrophysics Data System (ADS)

Organising Committee Kenneth Barish Huan Zhong Huang Joseph Kapusta Grazyna Odyniec Johann Rafelski Charles A Whitten Jr International Advisory Committee Jörg Aichelin Federico Antinori Tamas Biró Jean Cleymans Lazlo Csernai Tim Hallman Ulrich Heinz Sonja Kabana Rob Lacey Yu-Gang Ma Jes Madsen Yasuo Miake Berndt Mueller Grazyna Odyniec Helmut Oeschler Apostolos Panagiotou Johann Rafelski Hans Ritter Karel Safarik Jack Sandweiss Jürgen Schaffner-Bielich Wen-Qing Shen Georges Stephans Horst Stöcker Thomas Ullrich Bill Zajc

2006-12-01

264

Single-Scan Bayes Estimation of Cerebral Glucose Metabolic Rate: Comparison with Non-Bayes Single-Scan Methods Using FDG Pet Scans in Stroke  

Microsoft Academic Search

Summary: Three single-scan (SS) methods are currently available for estimating the local cerebral metabolic rate of glucose (LCMRG) from F-18 deoxyglucose (FDG) positron emission tomography (PET) scan data: SS(SPH), named for Sokoloff, Phelps, and Huang; SS(B), named for Brooks; and SS(H), named for Hut-chins and Holden et al. All three of these SS methods make use of prior information in

P. David Wilson; Sung-Cheng Huang; Randall A. Hawkins

1988-01-01

265

Comparisons Between Reliability-Based Iterative Min-Sum and Majority-Logic Decoding Algorithms for LDPC Codes  

Microsoft Academic Search

A modified reliability-based iterative majority-logic decoding (MRBI-MLGD) algorithm for two classes of structured LDPC codes is presented based on a recent work by Huang et al. Compared with the original one, the modified algorithm has better performance with slightly increased complexity. Then a reliability-based iterative min-sum decoding (RBI-MSD) al- gorithm is presented. For the presented RBI-MSD algorithm, reliability-based integer messages

Haiqiang Chen; Kai Zhang; Xiao Ma; Baoming Bai

2011-01-01

266

Exciton–vibrational coupling in pinwheel aggregates of ?-conjugated molecules  

Microsoft Academic Search

Absorption spectra of para-distyrylbenzene (DSB) aggregates are calculated based on a Hamiltonian which includes excitonic coupling between molecules, each containing a single electronic transition coupled to an intramolecular vibration (with frequency ?0 and Huang–Rhys factor ?2). Aggregates are based on the four-molecule pinwheel unit which maximizes the favorable edge–face interactions. Pinwheel aggregates of DSB lie within the intermediate coupling regime,

F. C. Spano; S. Siddiqui

1999-01-01

267

Regeneration of somatic hybrids of ginger via chemical protoplast fusion  

Microsoft Academic Search

Ginger (Zingiber officinale Rosc.) somatic hybridization was attempted by using polyethylene glycol (PEG)-mediated protoplast fusion. Protoplasts of\\u000a three ginger cultivars isolated from the embryogenic cell suspensions were fused with each other. The highest binary fusion\\u000a rate [13.5% in the fusion of ginger ‘Lushan Zhangliang jiang’ + ‘Chenggu Huang Jiang’ (LZ + CH)] was observed with the treatment\\u000a of 30% PEG6000 for 15 min. The three

Qiuzhu Guan; Yinghua Guo; Yuxia Wei; Fanzhen Meng; Zhenxian Zhang

2010-01-01

268

Limb Deficiency and Prosthetic Management. 3. Complex Limb Deficiency  

Microsoft Academic Search

Huang ME, Nelson VS, Flood KM, Roberts TL, Bryant PR, Pasquina PF. Limb deficiency and prosthetic management. 3. Complex limb deficiency.This self-directed learning module highlights rehabilitation and prosthetic issues associated with complex limb deficiencies. It is part of the chapter on acquired limb deficiencies in the Self-Directed Physiatric Education Program for practitioners and trainees in physical medicine and rehabilitation. This

Mark E. Huang; Virginia S. Nelson; Katherine M. Flood; Toni L. Roberts; Phillip R. Bryant; Paul F. Pasquina

2006-01-01

269

Fluorescence quenching: seeing two-dimensional sheets on arbitrary substrates by fluorescence quenching microscopy (small 19/2013).  

PubMed

Fluorescence quenching microscopy (FQM), an optical technique originally developed for imaging graphenebased sheets on arbitrary substrates is extended by J. Huang and co-workers on page 3253 to other two-dimensional materials, such as molybdenum disulfide (MoS2 ) sheets (background image). The panels in the main image are the MoS2 flakes imaged by reflectance mode optical microscopy (left), FQM (middle), and scanning electron microscopy (right). PMID:24101558

Tan, Alvin T L; Kim, Jaemyung; Huang, Jing-Kai; Li, Lain-Jong; Huang, Jiaxing

2013-10-11

270

Differential thermal analysis of the reaction properties of raw and retorted oil shale with air  

SciTech Connect

The results of a study to determine the kinetics of combustion of oil shale and its char by using differential thermal analysis are reported. The study indicates that Colorado oil shale and its char combustion rate is the fastest while Fushun oil shale and its char combustion rate is the slowest among the six oil shales used in this work. Oil shale samples used were Fushun oil shale, Maoming oil shale, Huang county oil shale, and Colorado oil shale.

Wang, T.F.

1984-01-01

271

Compositional characteristics and existing forms of major, trace and rare-earth elements in cassiterite, Dupangling tin ore field, Guangxi  

Microsoft Academic Search

Trace elements in cassiterite, including Ta, W, Fe, Mn, Ti, Zr, V, Sc, Si, Al, In, Ga, Ge, Be, Bi, Ag, Sb, As, Cu, Pb, Zn,\\u000a Co and REE, have been studied by many workers (Shan Zhenhua et al., 1988; Huang Zhou Tianren et al., 1987; Wu Qingsheng et\\u000a al., 1988; Hu Zening, 1988, Li Zhongqing 1988 Mingzhi et al.,

Guoliang Gan; Zhixiong Chen

1994-01-01

272

The medicinal plant goldenseal is a natural LDL-lowering agent with multiple bioactive components and new action mechanisms  

Microsoft Academic Search

Our previous studies have identified berberine (BBR), an alkaloid isolated from the Chinese herb huang- lian, as a unique cholesterol-lowering drug that upregulates hepatic low density lipoprotein receptor (LDLR) expression through a mechanism of mRNA stabilization. Here, we dem- onstrate that the root extract of goldenseal, a BBR-containing medicinal plant, is highly effective in upregulation of liver LDLR expression in

Parveen Abidi; Wei Chen; Fredric B. Kraemer; Hai Li; Jingwen Liu

2006-01-01

273

A Gradient-Based ELM Algorithm in Regressing Multivariable Functions  

Microsoft Academic Search

\\u000a A new off-line learning algorithm for single layer feed-forward neural networks (SLFNs) called Extreme Learning Machine (ELM)\\u000a was introduced by Huang et al. [1, 2, 3, 4]. ELM is not as the same as traditional BP method as it can achieve good generalization\\u000a performance at an extremely fast learning speed. In ELM, the hidden neuron parameters (the input weights and

You Xu

2006-01-01

274

Determination of the Donor-Acceptor Pair Separation in GaP Semiconductor Doped with Sulfur and Zinc Using its Photoluminescence Spectrum  

Microsoft Academic Search

Considering the gallium phosphide (GaP) semiconductors doped with sulfur (S) and zinc (Zn) acceptors, we have studied the behavior of Huang-Rhys factor Stheor as a function of the donor-acceptor (D-A) pair separation R. It turned out that the form of the bands --- broad or narrow --- that are attributed to (D-A) recombination, depends on the values of the pair

S. Baskoutas; N. S. Athanasiou

1997-01-01

275

The lipid dependence of antimicrobial peptide activity is an unreliable experimental test for different pore models.  

PubMed

Antimicrobial peptides usually kill bacteria by making their membranes permeable. Two main models (barrel-stave and Shai-Matsuzaki-Huang) have been proposed to describe the peptide-induced pores. Although several experimental tests can be exploited to discriminate between these two models, the dependence of peptide activity on lipid properties (intrinsic curvature and membrane thickness) is routinely used for this purpose. Here, we show that, contrary to what is currently accepted, this criterion is unreliable. PMID:23228161

Bobone, Sara; Roversi, Daniela; Giordano, Lorenzo; De Zotti, Marta; Formaggio, Fernando; Toniolo, Claudio; Park, Yoonkyung; Stella, Lorenzo

2012-12-13

276

Vibration analysis of plane elasticity problems by the C 0 -continuous time stepping finite element method  

Microsoft Academic Search

This paper proposes a C0-continuous time stepping finite element method to solve vibration problems of plane elasticity. In the time direction, unlike the existing methods [F. Costanzo, H. Huang, Proof of unconditional stability for a single-field discontinuous Galerkin finite element formulation for linear elasto-dynamics, Comput. Methods Appl. Mech. Engrg. 194 (2005) 2059–2076; D.A. French, A space–time finite element method for

Junjiang Lai; Jianguo Huang; Chuanmiao Chen

2009-01-01

277

Acquired limb deficiencies. 2. Perioperative management  

Microsoft Academic Search

Pandian G, Huang ME, Duffy DA. Acquired limb deficiencies. 2. Perioperative management. Arch Phys Med Rehabil 2001;82 Suppl 1:S9-16. This self-directed learning module highlights recent advances in the evaluation and management of complications arising from diabetes and peripheral vascular disease leading to amputation. It is part of the chapter on acquired limb deficiencies in the Self-Directed Physiatric Education Program for

Geetha Pandian; Mark E. Huang; Daniel A. Duffy

2001-01-01

278

PLCO Publications - 2006  

Cancer.gov

Chang, S.-C., Ziegler, R.G., Dunn, B., Stolzenberg-Solomon, R., Lacey Jr, J.V., Huang, W.-Y., Schatzkin, A., Reding, D., Hoover, R.N., Hartge, P. and Leitzmann, F.F. (2006) Association of energy intake and energy balance with postmenopausal breast cancer in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. Cancer Epidemiol Biomarkers Prev 2006 Feb.

279

Seed priming with chitosan improves maize germination and seedling growth in relation to physiological changes under low temperature stress  

Microsoft Academic Search

Low temperature stress during germination and early seedling growth is an important constraint of global production of maize.\\u000a The effects of seed priming with 0.25%, 0.50%, and 0.75% (w\\/v) chitosan solutions at 15 °C on the growth and physiological\\u000a changes were investigated using two maize (Zea mays L.) inbred lines, HuangC (chilling-tolerant) and Mo17 (chilling-sensitive). While seed priming with chitosan

Ya-jing Guan; Jin Hu; Xian-ju Wang; Chen-xia Shao

2009-01-01

280

Comment on ``Molecular-dynamics simulation of excess-electron transport in simple fluids''  

NASA Astrophysics Data System (ADS)

A recent treatment of the saturation drift velocity vsat of electrons in dense, supercritical argon [Leycuras and Levesque, Phys. Rev. A 32, 1180 (1985)] gives positive values of dvsat/dn at n/nc=1.2-1.6, whereas the experimental values are negative in both the supercritical gas and the liquid at these densities [Jahnke, Meyer, and Rice, Phys. Rev. A 3, 734 (1971); Huang and Freeman, Phys. Rev. A 24, 714 (1981)]. Other difficulties are mentioned.

Gee, Norman; Freeman, Gordon R.

1987-05-01

281

Photoinduced Effects of Polycyclic Aromatic Hydrocarbons on Brassica napus(Canola) during Germination and Early Seedling Development  

Microsoft Academic Search

It has recently been demonstrated that light dramatically enhances the toxicity of polycyclic aromatic hydrocarbons (PAHs) to the duckweedLemna gibbaL. G-3 (L. Ren, X.-D. Huang, B. J. McConkey, D. G. Dixon, and B. M. Greenberg, 1994,Ecotoxicol. Environ. Saf.28,160–171). To extend this research to terrestrial plants,Brassica napusL. (oil seed rape) seeds were germinated in the presence of three PAHs; anthracene (ANT),

Lisha Ren; Lorelei F. Zeiler; D. George Dixon; Bruce M. Greenberg

1996-01-01

282

Catalytic mechanism of S-adenosylhomocysteine hydrolase: Roles of His 54, Asp130, Glu155, Lys185, and Aspl89  

Microsoft Academic Search

S-Adenosylhomocysteine hydrolase (AdoHcyase) catalyzes the hydrolysis of S-adenosylhomocysteine (AdoHcy) to form adenosine and homocysteine. The crystal structure of the K185N mutated enzyme, which has weak catalytic activity (0.1%), has been determined at 2.8Å resolution and supports the previously predicted mechanism [Takata, Y., Yamada, T., Huang, Y., Komoto, J., Gomi, T., Ogawa, H., Fujioka, M., & Takusagawa, F. (2002). Catalytic mechanism

Taro Yamada; Yoshimi Takata; Junichi Komoto; Tomoharu Gomi; Hirofumi Ogawa; Motoji Fujioka; Fusao Takusagawa

2005-01-01

283

Influence On The Physical Universe By Wormhole Generated Extra Dimensional space  

Microsoft Academic Search

We use the Gu-Huang model for a special case when the universe is seven\\u000adimensional. In the core of extra dimension we place a modified\\u000aGidding-Strominger wormhole. This wormhole is separated by a thin wall from the\\u000aextra dimensional space. The wormhole content is assumed to satisfy the\\u000aadiabatic gas law. The wormhole pressure penetrates into the extra dimension.\\u000aWe

A. L. Choudhury

2003-01-01

284

A Microscopic Interaction Model of Maximum Solubility of Cholesterol in Lipid Bilayers  

Microsoft Academic Search

We recently reported the equilibrium maximum solubility of cholesterol in a lipid bilayer, ?*chol, to be 0.66 in four different phosphatidylcholines, and 0.51 in a phosphatidylethanolamine (Huang, J., J. T. Buboltz, and G. W. Feigenson. 1999. Biochim. Biophys. Acta. in press). Here we present a model of cholesterol-phospholipid mixing that explains these observed values of ?*chol. Monte Carlo simulations show

Juyang Huang; Gerald W. Feigenson

1999-01-01

285

Detailed analysis of evolution of the state of polarization in all-fiber polarization transformers  

Microsoft Academic Search

We present a detailed analysis of key attributes and performance characteristics of controllably-spun birefringent-fiber-based all-fiber waveplates or ``all fiber polarization transformers'' (AFPTs), first proposed and demonstrated by Huang [11]; these AFPTs consist essentially of a long carefully-designed ``spin-twisted'' high-birefringence fiber, fabricated by slowly varying the spin rate of a birefringent fiber preform (either from very fast to very slow or

Xiushan Zhu; Ravinder K. Jain

2006-01-01

286

STRUCTURAL BIOLOGY: Breaching the Barrier  

NSDL National Science Digital Library

Access to the article is free, however registration and sign-in are required. There are a huge number of membrane transporter proteins that transport molecules across the impermeable barrier presented by cellular membranes. In their Perspective, Locher et al. discuss a double tour de force (Abramson et al., Huang et al.), which provide structural determinations of two bacterial transporters, LacY and GlpT, and insights into how they work.

Kaspar P. Locher (Eidgenössische Technische Hochschule Zürich;Institut für Molekularbiologie und Biophysik); Randal B. Bass (California Institute of Technology;Division of Chemistry and Chemical Engineering); Douglas C. Rees (California Institute of Technology;Division of Chemistry and Chemical Engineering)

2003-08-01

287

Pattern Recognition of Surface EMG Biological Signals by Means of Hilbert Spectrum and Fuzzy Clustering  

Microsoft Academic Search

\\u000a A novel method for hand movement pattern recognition from electromyography (EMG) biological signals is proposed. These signals\\u000a are recorded by a three-channel data acquisition system using surface electrodes placed over the forearm, and then processed\\u000a to recognize five hand movements: opening, closing, supination, flexion, and extension. Such method combines the Hilbert–Huang\\u000a analysis with a fuzzy clustering classifier. A set of

Ruben-Dario Pinzon-Morales; Katherine-Andrea Baquero-Duarte; Alvaro-Angel Orozco-Gutierrez; Victor-Hugo Grisales-Palacio

288

Klippel-Trenaunay Syndrome  

Microsoft Academic Search

Klippel-Trenaunay syndrome is characterised by (a) combined vascular malformations of the capillary, venous, and lymphatic\\u000a types, (b) varicosities of unusual distribution, in particular a lateral venous anomaly observed during infancy or childhood,\\u000a and (c) limb enlargement with limb asymmetry (Berry et al. 1998; Cohen 2000, 2002, 2006; Cohen et al. 2002; Gorlin et al. 2001; Huang and Creath 1994).

Martino Ruggieri; Concezio Di Rocco; Orhan Konez

289

Regularized Extreme Learning Machine  

Microsoft Academic Search

Extreme learning machine proposed by Huang G-B has attracted many attentions for its extremely fast training speed and good generalization performance. But it still can be considered as empirical risk minimization theme and tends to generate over-fitting model. Additionally, since ELM doesn't considering heteroskedasticity in real applications, its performance will be affected seriously when outliers exist in the dataset. In

Wanyu Deng; Qinghua Zheng; Lin Chen

2009-01-01

290

Science Signaling Podcast: 7 December 2010  

NSDL National Science Digital Library

This is a conversation with Lan Huang about a Research Article published in the 7 December 2010 issue of Science Signaling. Wang and colleagues report that oxidative stress triggers separation of the catalytic and regulatory portions of the yeast proteasome, thus enabling the catalytic core to switch from degrading ubiquitinated proteins to degrading potentially toxic oxidized proteins. This response was also observed in human cells, suggesting that this mechanism for surviving oxidative stress might be conserved throughout eukaryotes.

Lan Huang (Irvine;University of California REV); Annalisa M. VanHook (American Association for the Advancement of Science;Science Signaling REV)

2010-12-07

291

Comment on ``Localization in a one-dimensional Thue-Morse chain''  

NASA Astrophysics Data System (ADS)

Using two distinct methods, Huang, Gumbs, and Kolár? [Phys. Rev. B 46, 11 479 (1992)] find different results for the calculated transmission coefficient through a chain of N ?-function-shaped barriers. We explain that the origin of this difference is an erroneous formulation of the so-called optical method and we give its corrent version. All of the important results of the cited paper, which were obtained using the transfer-matrix method, remain correct.

Liviotti, Emilia; Erdös, Paul

1995-02-01

292

Remote sensing assessment of sediment re-suspension during Hurricane Frances in Apalachicola Bay, USA  

Microsoft Academic Search

Assessments of hurricane-induced environmental impacts are important to coastal management and risk analysis of ecosystems. In this study, a previously-developed remote sensing model for non-hurricane conditions by Wang et al. [Wang, H. Q., Hladik, C. M., Milla, K., Huang, W. R., Edmiston, L., Harwell, M. A., & Schalles, J. F. (in press). Detecting and mapping water quality indicators in Apalachicola

Shuisen Chen; Wenrui Huang; Hongqing Wang; Dan Li

2009-01-01

293

From Education to Grassroots Learning: Towards a Civil Society Through Community Colleges in Taiwan  

Microsoft Academic Search

Since the 1980s, building a civil society has been a prevailing endeavor in many countries, including Taiwan, which want to\\u000a be transformed into more democratic states, where greater participation from citizens is expected in public affairs and decision-making\\u000a (Huang, 1997). Essentially, civil society refers to the arena that allows collective action to take place without bureaucratic\\u000a and institutional coercions over

Amy Shi-min Chen; Wei-ni Wang

294

Climate, traffic-related air pollutants and allergic rhinitis prevalence in middle-school children in Taiwan  

Microsoft Academic Search

Climate, traffic-related air pollutants and allergic rhinitis prevalence in middle-school children in Taiwan. Y-L. Lee, C-K. Shaw, H-J. Su, J-S. Lai, Y-C. Ko, S-L. Huang, F-C. Sung, Y.L. Guo. #ERS Journals Ltd 2003. ABSTRACT: The prevalence of allergic rhinitis, a common respiratory disorder, may be rapidly increasing. Epidemiological studies, however, indicate little about its association with climatic factors and air

Y. L. Lee; H. J. Su; J. S. Lai; S. L. Huang; Y. L. Guo

2003-01-01

295

GLLS for optimally sampled continuous dynamic system modeling: theory and algorithm  

Microsoft Academic Search

The original generalized linear least squares (GLLS) algorithm was developed for non-uniformly sampled biomedical system parameter estimation using finely sampled instantaneous measurements (D. Feng, S.C. Huang, Z. Wang, D. Ho, An unbiased parametric imaging algorithm for non-uniformly sampled biomedical system parameter estimation, IEEE Trans. Med. Imag. 15 (1996) 512–518). This algorithm is particularly useful for image-wide generation of parametric images

D. Feng; D. Ho; K. K. Lau; W. C. Siu

1999-01-01

296

Assessment of intermittency transport equations for modeling transition in boundary layers subjected to freestream turbulence  

Microsoft Academic Search

The ?–Re? transition model of Menter et al. [Menter, F.R., Langtry, R.B., Volker, S., Huang, P.G., 2005. Transition modelling for general purpose CFD codes. ERCOFTAC International Symposium Engineering Turbulence Modelling and Measurements] is a highly generalized transport equation model in which it has been developed based on the concept of local variables compatible with modern CFD methods where the unstructured

Keerati Suluksna; Ekachai Juntasaro

2008-01-01

297

The coIR4 and colR15 B-Tubulin Mutations in Chlamydomonas reinhardtii Confer Altered Sensitivities to Microtubule Inhibitors and Herbicides by Enhancing Microtubule Stability  

Microsoft Academic Search

The colR4 and co1R15 B2-tubulin missense mutations for lysine-350 in Chlamydomonas reinhard- tii (Lee and Huang, 1990) were originally isolated by selection for resistance to the growth inhibitory effects of colchicine. The coIR4 and colR15 mutants have been found to be cross resistant to vinblastine and several classes of antimitotic herbicides, including the dinitroanilines (oryzalin, trifluralin, profluralin, and ethafluralin); the

Matthew J. Schibler; Bessie Huang

298

Identification of the optically active vibrational modes in the photoluminescence of MEH-PPV films  

Microsoft Academic Search

The temperature dependence of the photoluminescence properties of a thin film of poly[2-methoxy-5-(2?-ethylhexyloxy)-p-phenylene-vinylene], MEH-PPV, fabricated by spin coating, is analyzed. The evolution with temperature of the peak energy of the purely electronic transition, of the first vibronic band, of the effective conjugation length, and of the Huang–Rhys factors are discussed. The asymmetric character of the pure electronic transition peak and

M. A. T. da Silva; I. F. L. Dias; J. L. Duarte; E. Laureto; I. Silvestre; L. A. Cury; P. S. S. Guimarães

2008-01-01

299

Identification of the optically active vibrational modes in the photoluminescence of MEH-PPV films  

Microsoft Academic Search

The temperature dependence of the photoluminescence properties of a thin film of poly[2-methoxy-5-(2'-ethylhexyloxy)-p-phenylene-vinylene], MEH-PPV, fabricated by spin coating, is analyzed. The evolution with temperature of the peak energy of the purely electronic transition, of the first vibronic band, of the effective conjugation length, and of the Huang-Rhys factors are discussed. The asymmetric character of the pure electronic transition peak and

M. A. T. da Silva; I. F. L. Dias; J. L. Duarte; E. Laureto; I. Silvestre; L. A. Cury

2008-01-01

300

Neuroprotective Potential of Fasudil Mesylate in Brain Ischemia-Reperfusion Injury of Rats  

Microsoft Academic Search

We previously reported that inhibition of Rho-kinase (ROCK) by hydroxyl fasudil improves cognitive deficit and neuronal damage\\u000a in rats with chronic cerebral ischemia (Huang et al., Cell Mol Neurobiol 28:757–768, 2008). In this study, fasudil mesylate\\u000a (FM) was investigated for its neuroprotective potential in rats with ischemia following middle cerebral artery occlusion (MCAO)\\u000a and reperfusion. The effect of fasudil mesylate

Qin Li; Xian-Ju Huang; Wei He; Jie Ding; Jun-Ting Jia; Gang Fu; Hong-Xing Wang; Lian-Jun Guo

2009-01-01

301

4th Annual Early Detection Research Network (EDRN) Scientific Workshop, Philadelphia, PA  

Cancer.gov

Speakers, Moderators, and Chairs Stephen Baylin Johns Hopkins University Tim Bestor Columbia University W. Debinsky Univ. of Pennsylvania Andy Feinberg Johns Hopkins University James Herman Johns Hopkins University Tim Huang Ellis Fischel Cancer Center Jean-Pierre Issa M.D. Anderson Cancer Center Peter Jones Univ. of Southern California (Workshop Chair) Peter Laird Univ. of Southern California David Sidransky Johns Hopkins University Dominic Smiraglia Ohio State University Benjamin Tycko Columbia University Fyodor Urnov Sangamo Biosciences Keith Wilson Univ.

302

Identification of genes for bone mineral density variation by computational disease gene identification strategy  

Microsoft Academic Search

We previously used five freely available bioinformatics tools (Prioritizer, Geneseeker, PROSPECTR and SUSPECTS, Disease Gene\\u000a Prediction, and Endeavour) to analyze the thirteen well-replicated osteoporosis susceptibility loci and identify a subset\\u000a of most likely candidate osteoporosis susceptibility genes (Huang et al. in J Hum Genet 53:644–655, 2008). In the current study, we experimentally tested the association between bone mineral density (BMD)

Gloria H. Y. LiHong-Wen; Hong-Wen Deng; Annie W. C. Kung; Qing-Yang Huang

303

Anselmella malacia , a new pest wasp (Hymenoptera: Chalcidoidea: Eulophidae) reared from Syzygium samarangense in Malaysia  

Microsoft Academic Search

A new pest wasp,Anselmella malacia Xiao & Huang sp. nov. (Hymenoptera: Eulophidae), is described fromSyzygium samarangense Merr. & Perry. The larvae ofAnselmella are phytophagous and develop as seed-eaters of some species ofSyzygium. This is the first record of anAnselmella species reared fromSyzygium samarangense. The type specimens are deposited in the Institute of Zoology, Chinese Academy of Sciences, Beijing.

Hui Xiao; Ling-Na Xu; Da-Wei Huang; Zhong-Yi Zhao

2006-01-01

304

A comparative evaluation of modern English corpus grammatical annotation schemes  

Microsoft Academic Search

Many English Corpus Linguistics projects reported in ICAME Journal and else-where involve grammatical analysis or tagging of English texts (eg Atwell 1983, Leech et al 1983, Booth 1985, Owen 1987, Souter 1989a, O'Donoghue 1991, Belmore 1991, Kyt? and Voutilainen 1995, Aarts 1996, Qiao and Huang 1998). Each new project has to review existing tagging schemes, and decide which to adopt

Eric Atwell; George Demetriou; John Hughes; Amanda Schiffrin; Clive Souter; Sean Wilcock

305

The bare essentials. Release of LOM report leaves HHS to determine what should be covered by health benefits packages.  

PubMed

In the wake of an IOM report on the criteria HHS should use to determine what benefits will be "essential" under reform, various stakeholders are weighing in. The National Association of Public Hospitals and Health Systems would like "enabling" services--such as language, transportation and case-management services--included, because they help make medical care more effective, says Xiaoyi Huang, left, of the NAPH. PMID:22111491

Zigmond, Jessica

2011-10-10

306

Widespread dispersal of the microsporidian Nosema ceranae, an emergent pathogen of the western honey bee, Apis mellifera  

Microsoft Academic Search

The economically most important honey bee species, Apis mellifera, was formerly considered to be parasitized by one microsporidian, Nosema apis. Recently, [Higes, M., Martín, R., Meana, A., 2006. Nosema ceranae, a new microsporidian parasite in honeybees in Europe, J. Invertebr. Pathol. 92, 93–95] and [Huang, W.-F., Jiang, J.-H., Chen, Y.-W., Wang, C.-H., 2007. A Nosema ceranae isolate from the honeybee

Julia Klee; Andrea M. Besana; Elke Genersch; Sebastian Gisder; Antonio Nanetti; Dinh Quyet Tam; Tong Xuan Chinh; Francisco Puerta; José Maria Ruz; Per Kryger; Dejair Message; Fani Hatjina; Seppo Korpela; Ingemar Fries; Robert J. Paxton

2007-01-01

307

A note on “A fast high-resolution method for bearing estimation in shallow ocean”  

Microsoft Academic Search

In the referenced paper [by Jin, Huang, Zhang, and Hou, Multidimensional Systems and Signal Processing, 20(4): 397–406, 2009],\\u000a a rank-reduction based direction finding algorithm called Rayleigh MUSIC (R-MUSIC) is proposed to deal with the multimode\\u000a nature of the acoustic propagation in the shallow ocean. However, when a linear array is utilized, R-MUSIC degrades severely\\u000a for sources located in the vicinity

Yougen Xu; Zhiwen Liu

308

East meets West: an herbal tea finds a receptor  

PubMed Central

Jaundice, which is caused by accumulation of bilirubin, is extremely common in newborn infants. Phototherapy is an effective treatment, but a drug therapy would also be desirable. A Chinese herbal remedy for jaundice called Yin Zhi Huang is now shown to activate a liver receptor that enhances the clearance of bilirubin (see the related article beginning on page 137). This discovery could lead to improved pharmaceutical treatments for neonatal jaundice.

Lazar, Mitchell A.

2004-01-01

309

Recent changes in the summer precipitation pattern in East China and the background circulation  

Microsoft Academic Search

This study documents the decadal changes of the summer precipitation in East China, with increased rainfall in the Huang-Huai\\u000a River region (HR) and decreased in the Yangtze River region (YR) during 2000–2008 in comparison to 1979–1999. The main features\\u000a of the atmospheric circulation related to the increased precipitation in the HR are the strengthened ascending motion and\\u000a slightly increased air

Yali ZhuHuijun; Huijun Wang; Wen Zhou; Jiehua Ma

2011-01-01

310

An agent-based English auction protocol using Elliptic Curve Cryptosystem for mobile commerce  

Microsoft Academic Search

Rapid development of the Internet and the extensive use of mobile phones have increased demand for mobile devices in Internet auctions. This trend is acting as an incentive to develop an auction model for mobile-based environment. Recently, Kuo-Hsuan Huang proposed a mobile auction agent model (MoAAM), which allows the bidders to participate in online auctions through a mobile agent. He

Yu-Fang Chung; Yu-Ting Chen; Tzer-Long Chen; Tzer-Shyong Chen

2011-01-01

311

Inhibitory Effects of Curcumin on in Vitro Lipoxygenase and Cyclooxygenase Activities in Mouse Epidermis1  

Microsoft Academic Search

Topical application of curcumin, the yellow pigment in turmeric and curry, strongly inhibited 12-O-tetradecanoylphorbol-13-acetate (TPA)- induced ornithine decarboxylase activity, DNA synthesis, and tumor promotion in mouse skin (Huang et al., Cancer Res., 48: 5941-5946, 1988). Chlorogenic acid, caffeic acid, and ferulic acid (structurally related dietary compounds) were considerably less active. In the present study, topical application of curcumin markedly inhibited

Mou-Tuan Huang; Thomas Lysz; Thomas Ferrara; Tanveer F. Abidi; Jeffrey D. Laskin; Allan H. Conney

312

Content versus label claims in ephedra-containing dietary supplements  

Microsoft Academic Search

The content of ephedra alkaloids in herbal dietary supplements containing ephedra (ma huang) was studied. The ephedra alkaloid content of 20 ephedra-containing supplements was de- termined by high-performance liquid chromatography. Contents of (-)-ephed- rine, (+)-pseudoephedrine, (-)-methyle- phedrine, (-)-norephedrine, and (+)-nor- pseudoephedrine were measured. Ephedra alkaloid content varied consid- erably among products. Total alkaloid con- tent ranged from 0.0 to 18.5

BILL J. GURLEY; STEPHANIE F. GARDNER; MARTHA A. HUBBARD

313

Advances in Amputee Care  

Microsoft Academic Search

Pasquina PF, Bryant PR, Huang ME, Roberts TL, Nelson VS, Flood KM. Advances in amputee care.This self-directed learning module highlights the recent innovations in amputee care. It is part of the study guide on limb deficiency in the Self-Directed Physiatric Education Program for practitioners and trainees in physical medicine and rehabilitation. This focused review article describes the key elements of

Paul F. Pasquina; Phillip R. Bryant; Mark E. Huang; Toni L. Roberts; Virginia S. Nelson; Katherine M. Flood

2006-01-01

314

PLCO Publications - 2009  

Cancer.gov

Ahn, J., Albanes, D., Berndt, S.I., Peters, U., Chatterjee, N., Freedman, N.D., Abnet, C.C., Huang, W.-Y., Kibel, A.S., Crawford, E.D., Weinstein, S.J., Chanock, S.J., Schatzkin, A. and Hayes, R.B. for the Prostate, Lung, Colorectal and Ovarian Trial Project Team. (2009) Vitamin D-related genes, serum vitamin D concentrations, and prostate cancer risk. Carcinogenesis 2009 May. (Epub ahead of print).

315

Treatment of acute bronchiolitis with Chinese herbs.  

PubMed Central

In a randomised single blind trial the Chinese herbs Shuang Huang Lian were evaluated for the treatment of acute bronchiolitis. Children with acute bronchiolitis and serological evidence of recent respiratory syncytial virus infection were studied in a tertiary hospital in Harbin, China. The 96 children were randomised into three treatment groups: herbs, herbs with antibiotics, and antibiotics alone. The herbs were prepared by the medical school pharmacy and administered daily by intravenous infusion for seven days. The main outcomes, assessed blindly, were symptomatic improvement in cough, fever, wheezing, chest signs, and duration of stay in hospital. The mean duration of symptoms from the start of treatment was 6.2 (confidence interval 5.6 to 6.9) days in the two groups treated with herbs compared with 8.6 (confidence interval 7.5 to 9.8) days in the group treated with antibiotics alone. The mean reductions in duration of clinical manifestations for treatment with antibiotics alone compared with herbs were: from 3.1 to 1.5 days for fever, 9.1 to 6.1 days for cough, 6.5 to 4.1 days for wheezing, and 7.2 to 4.9 days for chest crackles. No adverse effect of Shuang Huang Lian herbal treatment was detected. In conclusion, this study confirms Chinese experience with Shuang Huang Lian that it is safe and effective, and warrants further study.

Kong, X T; Fang, H T; Jiang, G Q; Zhai, S Z; O'Connell, D L; Brewster, D R

1993-01-01

316

Surface light-scattering at the air-liquid interface: from newtonian to viscoelastic polymer solutions.  

PubMed

The dynamics of the liquid-air interface of aqueous solutions of a tensioactive triblock copolymer (Pluronic F-68) has been studied using surface quasielastic light scattering over a broad range of concentrations and temperatures. Ancillary surface tension and bulk rheometry data have been obtained for the same system. The results show that the classical theoretical spectrum for monolayers on a Newtonian fluid can be applied only for concentrations below 4.10(-2) mM. For concentrations above c = 14 mM a clear peak centered at zero frequency appears in the spectrum. This feature is incompatible with the classical theoretical spectrum. The SQELS spectra have been described in terms of the theory of Wang and Huang [Wang, C. H.; Huang, Q. R. J. Chem. Phys. 1997, 107, 5898] considering that the loss modulus of the concentrated solutions shows the existence of two relaxation modes even at low frequencies. The theory is able to explain the existence of a peak centered at zero frequency in the spectra, and the theoretical spectra point out the existence of an elastic peak together with the capillary one. There is a reasonable agreement between the relaxation times and the product Gtau obtained from the fits of the SQELS spectra to the theory of Wang and Huang and those obtained from bulk rheology. PMID:16851550

Muñoz, Mercedes G; Encinar, Mario; Bonales, Laura J; Ortega, Francisco; Monroy, Francisco; Rubio, Ramón G

2005-03-17

317

Treatment of acute bronchiolitis with Chinese herbs.  

PubMed

In a randomised single blind trial the Chinese herbs Shuang Huang Lian were evaluated for the treatment of acute bronchiolitis. Children with acute bronchiolitis and serological evidence of recent respiratory syncytial virus infection were studied in a tertiary hospital in Harbin, China. The 96 children were randomised into three treatment groups: herbs, herbs with antibiotics, and antibiotics alone. The herbs were prepared by the medical school pharmacy and administered daily by intravenous infusion for seven days. The main outcomes, assessed blindly, were symptomatic improvement in cough, fever, wheezing, chest signs, and duration of stay in hospital. The mean duration of symptoms from the start of treatment was 6.2 (confidence interval 5.6 to 6.9) days in the two groups treated with herbs compared with 8.6 (confidence interval 7.5 to 9.8) days in the group treated with antibiotics alone. The mean reductions in duration of clinical manifestations for treatment with antibiotics alone compared with herbs were: from 3.1 to 1.5 days for fever, 9.1 to 6.1 days for cough, 6.5 to 4.1 days for wheezing, and 7.2 to 4.9 days for chest crackles. No adverse effect of Shuang Huang Lian herbal treatment was detected. In conclusion, this study confirms Chinese experience with Shuang Huang Lian that it is safe and effective, and warrants further study. PMID:8503668

Kong, X T; Fang, H T; Jiang, G Q; Zhai, S Z; O'Connell, D L; Brewster, D R

1993-04-01

318

Relative changes in genetic variability and correlations in an early-maturing maize population during recurrent selection.  

PubMed

Four cycles of S(1) family recurrent selection to improve grain yield and resistance to Striga hermonthica have been completed in TZE-Y Pop STR C(0.) In order to determine whether or not to continue with the recurrent scheme, it was desirable to evaluate the amount of residual genetic variance and associated parameters in the population. The objective of this study was to characterize the relative changes in the levels of the genetic variances, heritability estimates and genetic correlation coefficients, and to predict future gains from selection for grain yield, Striga resistance and other agronomic traits. Fifty S(1) families, derived from each cycle, were evaluated under Striga-infested and Striga-free conditions at Mokwa, Ikenne and Abuja, Nigeria, in 2005 and 2007. Under Striga infestation, genetic variances for grain yield, days to anthesis, plant height and Striga damage generally increased in the advanced cycles of selection. In contrast, the genetic variances for days to silk, anthesis-silking interval, ears per plant, ear aspect and number of emerged Striga plants decreased with selection. The advanced cycles of selection significantly out-yielded the original cycle in both research environments. Heritabilities for grain yield, Striga damage and number of emerged Striga plants were significantly greater than zero. The realized gains from selection for grain yield under Striga infestation (52 kg ha(-1) cycle(-1)) and Striga-free conditions (130 kg ha(-1) cycle(-1)) were remarkably lower than the predicted gains (350 and 250 kg ha(-1 )cycle(-1), respectively). Adequate genetic variability exists in cycle 4 of the scheme to ensure future gains from selection. PMID:22722392

Badu-Apraku, B; Akinwale, R O; Fakorede, M A B; Oyekunle, M; Franco, J

2012-06-22

319

How should doctors approach patients? A Confucian reflection on personhood  

PubMed Central

The modern doctor-patient relationship displays a patient-centred, mutual-participation characteristic rather than the former active-passive or guidance-cooperation models in terms of medical decision making. Respecting the wishes of patients, amounting to more than mere concern for their welfare, has become the feature central to certain modern bioethics theories. A group of ethical principles such as respect for autonomy, beneficence, non-maleficence, and justice has been proposed by bioethicists and widely adopted by many medical societies as an ethical guide to how doctors, in their daily practice, should treat their patients. However, seeing patients as persons who are rational, self-conscious beings capable of valuing their own lives, and who are consequently entitled to the liberty and rights to choose for themselves, is in general the backbone of Western bioethical principles. Since Confucian philosophy has long been a representative of the East-Asia cultural tradition and Confucian bioethics has recently been developed as a theory of applied ethics, examining Confucius's idea of "persons" may shed some light on the current bioethical debates. Confucius's concept of persons, which is best interpreted via his theories of "chun-tze", (the morally ideal person) encapsulating a two-dimensional approach, (the "autonomous person" and the "relational person"), provides a more comprehensive model regarding what a person is and how he/she should be treated. This two-dimensional approach sees a person not only as a rational, autonomous agent but also as a relational, altruistic identity whose self actualisation involves incessant participating in and promoting of the welfare of his fellow persons. Hence this may balance the current bioethical trend whereby "respect for autonomy" often triumphs. Key Words: Personhood • autonomy • Confucian ethics • physician-patient relationship • principle-oriented bioethics

Tsai, D. F.

2001-01-01

320

Fabrication and properties of silicon carbide nanowires  

NASA Astrophysics Data System (ADS)

Silicon carbide (SiC), with excellent electrical, thermal, and mechanical properties, is a promising material candidate for future devices such as high-temperature electronics and super-strong lightweight structures. Combined with superior intrinsic properties, the nanomaterials of SiC show further advantages thanks to nanoscale effects. This thesis reports the growth mechanism, the self-integration, and the friction of SiC nanowires. The study involves nanowires fabrication using thermal evaporation, structure characterization using electron microscopy, friction measurement, and theoretical modeling. The study on nanowire growth mechanism requires understanding of the surfaces and interfaces of nanowire crystal. The catalyzed growth of SiC nanowires involves interfaces between source vapor, catalytic liquid, and nanowire solid. Our experimental observation includes the periodical twinning in a faceted SiC nanowire and three stage structure transitions during the growth. The proposed theoretical model shows that such phenomenon is the result of surface energy minimization process during the catalytic growth. Surface interactions also exist between nanowires, leading to their self-integration. Our parametric growth study reveals novel self-integration of SiC-SiO 2 core-shell nanowires as a result of SiO2 joining. Attraction between nanowires through van der Waals force and enhanced SiO2 diffusion at high temperature transform individual nanowires to the integrated nanojunctions, nanocables, and finally nanowebs. We also show that such joining process becomes effective either during growth or by annealing. The solid friction is a result of the interaction between two solid surfaces, and it depends on the adhesion and the deformation of two contacting solids among other factors. Having strong adhesion as shown from gecko foot-hairs, nanostructured materials should also have strong friction; this study is the first to investigate friction of nanostructures under (compressive) normal loads. Here, we show that the friction forces of SiC nanowires films is 5--12 that of macroscopic solids. For nanowires films, the maximum static frictional force varies linearly with, but is not proportional to, normal load; it increases linearly with interface area; and it is independent of loading speed. To summarize, the combined experimental and theoretical studies in this thesis demonstrated unique structures and surface properties of SiC nanowires, including: (1) Periodical twinning, surface faceting, and structure transition, [Shim & Huang, Appl. Phy. Lett. 90, 083106] (2) Twinning growth mechanism, [Shim, Zhang & Huang, J. Appl. Phys., submitted; Zhang, Shim, & Huang, Appl. Phys. Lett. 92, 261908] (3) Self-integration (nanowebs formation) during growth, [Shim & Huang, Nanotechnology 18, 335607] (4) Thermal stability and self-integration by annealing, [Shim, Kuppers & Huang, J. Nanosci. Nanotech. 8, 3999] and (5) Strong friction of nanowires film. [Shim, Kuppers & Huang, NATURE Nanotech., submitted] The collection of these results enhances the understanding of SiC nanowires growth, the better control of their microstructure and integration, and the application of ceramic nanowires as friction material at high temperature.

Shim, Hyun Woo

321

Comment on ``Dynamics of glass-forming liquids. XIII. Microwave heating in slow motion'' [J. Chem. Phys. 130, 194509 (2009)  

NASA Astrophysics Data System (ADS)

Critical reading of the dielectric method and data in the paper [W. Huang and R. Richert, J. Chem. Phys. 130, 194509 (2009)] showed that (i) the large inter-electrode area of the Teflon spacer used in the dielectric cell affected the spectral data and (ii) the measured ?? of propylene carbonate after making the spacer area correction is 1.8-times the known value, indicating errors from unknown sources. This puts into question their support for the dynamic heterogeneity view, and their inference on the magnitude of configurational heat capacity.

Johari, G. P.

2012-07-01

322

On vortex dust structures in magnetized dusty plasmas  

SciTech Connect

To explain the generation of vortex patterns of dust grains in a magnetized dusty plasma [Huang et al., Plasma Sci. Technol. 9, 1 (2007)], a time dependent nonlinear model that describes vortices as a result of an instability is proposed. Grain-grain as well as grain-ion interactions, particle attachment, and grains drift and diffusion are key elements in the present model. It is found that the latter reproduces the experimental results quite well, whereas the stability analysis shows that the vortex core is grain size dependent.

Nebbat, E.; Annou, R. [Faculty of Physics, USTHB, Algiers 16111 (Algeria)

2010-09-15

323

Which Is the Optimal Risk Stratification System for Surgically Treated Localized Primary GIST? Comparison of Three Contemporary Prognostic Criteria in 171 Tumors and a Proposal for a Modified Armed Forces Institute of Pathology Risk Criteria  

Microsoft Academic Search

Background  This study aims to validate and compare the performance of the National Institute of Health (NIH) criteria, Huang modified\\u000a NIH criteria, and Armed Forces Institute of Pathology (AFIP) risk criteria for gastrointestinal stromal tumors (GISTs) in\\u000a a large series of localized primary GISTs surgically treated at a single institution to determine the ideal risk stratification\\u000a system for GIST.\\u000a \\u000a \\u000a \\u000a Methods  The clinicopathological

Brian K. P. Goh; Pierce K. H. Chow; Wai-Ming Yap; Sittampalam M. Kesavan; In-Chin Song; Pradeep G. Paul; Boon-Swee Ooi; Yaw-Fui A. Chung; Wai-Keong Wong

2008-01-01

324

Modeling of pervaporation with latex membranes  

SciTech Connect

Latex membranes have shown potential to be a new type of pervaporation separation membrane. Three types of latex membranes were prepared in our laboratory by direct casting of polymer latexes. These latex membranes were selective toward water during pervaporation with ethanol-water mixtures. The free-volume approach was employed to characterize the pervaporation of these latex membranes. It is shown by this experiment that the Yeom-Huang model, which is based on the free-volume theory and the thermodynamics, can be used to model the pervaporation process of the latex membranes which give reasonable predictions on the permeability. 18 refs., 3 figs., 8 tabs.

Huang, R.Y.M.; Wei, Y. (Univ. of Waterloo, Ontario (Canada))

1994-06-01

325

Existence and global exponential stability of periodic solution to BAM neural networks with periodic coefficients and continuously distributed delays  

NASA Astrophysics Data System (ADS)

By using the continuation theorem of coincidence degree theory and Liapunov function, we obtain some sufficient criteria to ensure the existence and global exponential stability of periodic solution to the bidirectional associative memory (BAM) neural networks with periodic coefficients and continuously distributed delays. These results improve and generalize the works of papers [J. Cao, L. Wang, Phys. Rev. E 61 (2000) 1825] and [Z. Liu, A. Chen, J. Cao, L. Huang, IEEE Trans. Circuits Systems I 50 (2003) 1162]. An example is given to illustrate that the criteria are feasible.

Zhou, distributed delays [rapid communication] T.; Chen, A.; Zhou, Y.

2005-08-01

326

Comment on ``Development of panel loudspeaker system: Design, evaluation and enhancement'' [J. Acoust Soc. Am. 106, 2751-2761 (2001)] (L)  

NASA Astrophysics Data System (ADS)

This letter concerns the paper ``Development of panel loudspeaker system: Design, evaluation and enhancement'' [M. R. Bai and T. Huang, J. Acoust. Soc. Am. 109, 2751-2761 (2001)]. It is suggested that the radiation field generated by the near vibration field induced by a point force acting on the plate has been neglected. It is pointed out that its relative contribution is crucially dependent upon the mechanical loss factor of the panel, for which no data are presented. The conclusion that the radiated power per unit mean square force is independent of frequency neglects the radiation efficiency factor. Other perceived shortcomings of the paper are noted.

Fahy, Frank

2003-01-01

327

Separation and determination of anthraquinone derivatives in rhubarb and its preparations by micellar electrokinetic capillary chromatography.  

PubMed

A micellar electrokinetic capillary chromatographic method was set up for the quality control of rhubarb and its preparations. Anthraquinone derivatives were separated successfully within 10 min in the buffer solution of 50 mmol/L H3BO3-NaOH (pH 11) containing 25 mmol/L sodium deoxycholate. The established method, with a recovery of extraction of over 90%, has good linear relationship and reproducibility. The contents of anthraquinone derivatives in rhubarb and a tablet of Niu-huang-jie-du differed significantly, showing that the quality control of rhubarb and its preparations is necessary. PMID:9861493

Ji, S G; Chai, Y F; Wu, Y T; Yin, X P; Xiang, Z B; Liang, D S; Xu, Z M; Li, X

328

VideoLab: Breaking the 3-D Diffraction Limit  

NSDL National Science Digital Library

"Super-resolution" fluorescence microscopy has allowed researchers to break the diffraction limit of visible light and achieve near-molecular image resolutions -- in two spatial dimensions. Huang et al. pushed that advantage into 3D, through a stochastic approach that takes advantage of optical astigmatism to determine both the axial and lateral positions of individual molecules with nanometer accuracy. In this movie, they show a 3D "STORM" image of five microtubule filaments from a monkey kidney cell; the scale bar is 200 nanometers in length.

Bo Huang (Howard Hughes Medical Institute, Harvard University;Department of Chemistry and Chemical Biology); Wenquin Wang (Harvard University, Cambridge, MA ;Department of Physics); Mark Bates (Harvard University, Cambridge, MA ;School of Engineering and Applied Sciences); Xiaowei Zhuang (Howard Hughes Medical Institute, Harvard University, Cambridge, MA;Department of Chemistry and Chemical Biology and Department of Physics)

2008-02-08

329

Effect of Dietary Supplementation of Galactomannan oligosaccharides and Chitosan on Performance and Serum Immune Parameters of 28-day Weaned Piglets Challenged with Pathogenic E.coli  

Microsoft Academic Search

Sun, Z.H., Tang, Z.R., Yin, Y.L., Huang, R.L., Li, T.J., Tang, S.X. and Tan, Z.L. 2009. Effect of dietary supplementation of galacto-mannan-oligosaccharides and chitosan on performance and serum immune parameters of 28-day weaned piglets challenged with pathogenic E. coli. J. Appl. Anim. Res., 36: 207–211.To determine the effects of galacto-mannan-oligosaccharides (GMOS) and chitosan (COS) on growth performance and serum immune

Z. H. Sun; Z. R. Tang; Y. L. Yin; R. L. Huang; T. J. Li; S. X. Tang; Z. L. Tan

2009-01-01

330

DETERMINATION OF ARISTOLOCHIC ACID IN TRADITIONAL CHINESE MEDICINAL PRESCRIPTIONS, CONTAINING RADIX ARISTOLOCHIAE FANGCHI, BY HPLC  

Microsoft Academic Search

A high performance liquid chromatographic method for determination of aristolochic acid, a nephrotoxicant in traditional Chinese medicinal prescriptions containing Radix Aristolochiae Fangchi, was established. (The prescriptions included Mu-Fang-Ji-Tang, Fang-Ji-Huang-Qi-Tang, Shu-Jing-Huo-Xue-Tang, Xiao-Xu-Ming-Tang, Shang-Zhong-Xia-Tong-Yong-Tong-Feng-Fang, and Fang-Ji-Fu-Ling-Tang.) The samples were analyzed by HPLC on a LiChrospher 100 RP-18e column and detected at 395?nm with acetonitrile water and 2% (v\\/v) acetic acid (45?:?55, v\\/v)

Yuan-Shiun Chang; Jeng-Shyan Deng; Yoe-Ray Ku

2002-01-01

331

Communications, customs, organization slowed project  

SciTech Connect

This paper reports that completion of a recently commissioned pipeline automation system in China overcame delays caused by serious difficulties in communications, organization, customs, and distance. The 153 mile, 28 in. hot-oil pipeline is located in the Shangdong Province, east of Beijing, China, and runs from Dongying, in the Shengli oil field, to the port of Huangdao on the Yellow Sea. The Shengli Oil Pipeline Co. (SOPC) now operates the fully automated Dong-Huang liquid pipeline with capability for central control in Weifang.

Blair, J.T. (Novacorp International Consulting Inc., Calgary (CA))

1992-09-21

332

[Similarity measures between vague sets and their application to electrocardiogram auto-recognition].  

PubMed

The similarity measures between Vague sets are one of the most important technologies in Vague sets, In this paper, the new similarity measures based on Huang Guoshun's related works are presented and applied in electrocardiogram auto-recognition. Based on medical requiresments, in this paper, the characteristic parameters of signals from Massachusettes Institute of Technology (database) have been picked up and studied with BP neural network. In the end, the electrocardiogram samples are classified with the use of those characteristic parameters. The result shows that the accuracy of recognition goes up to 99.04%. PMID:18788280

Tang, Li; Zhang, Xiaoyun; Tang, Xiao; Mo, Zhiwen

2008-08-01

333

Herbal ephedra\\/caffeine for weight loss: a 6-month randomized safety and efficacy trial  

Microsoft Academic Search

Objective: To examine long-term safety and efficacy for weight loss of an herbal Ma Huang and Kola nut supplement (90\\/192 mg\\/day ephedrine alkaloids\\/caffeine).Design: Six-month randomized, double-blind placebo controlled trial.Subjects: A total of 167 subjects (body mass index (BMI) 31.8±4.1 kg\\/m2) randomized to placebo (n=84) or herbal treatment (n=83) at two outpatient weight control research units.Measurements: Primary outcome measurements were changes

CN Boozer; PA Daly; P Homel; JL Solomon; D Blanchard; JA Nasser; R Strauss; T Meredith

2002-01-01

334

COMMITTEES: SQM2004 Organising and International Advisory Committees  

NASA Astrophysics Data System (ADS)

Organising Committee Jean Cleymans (Chairman) Zeblon Vilakazi Roger Fearick Peter Steinberg Rory Adams Bruce Becker Sarah Blyth Gareth de Vaux Heather Gray Mark Horner Nawahl Razak Artur Szostak Spencer Wheaton International Advisory Committee Federico Antinori Tim Hallman John Harris Tetsuo Hatsuda Ulrich Heinz Huan Z Huang Sonja Kabana Volker Koch Rob Lacey Jes Madsen Yasuo Miake Maurizio Morando Berndt Mueller Grazyna Odyniec Helmut Oeschler Apostolos Panagiotou Josef Pochodzalla Johann Rafelski Karel Safarik Jack Sandweiss Jürgen Schaffner-Bielich Georges Stephans Horst Stoecker Herbert Stroebele Thomas Ullrich Orlando Villalobos-Baillie Bill Zajc Joseph Zimanyi

2005-06-01

335

Hippocrates, cardiology, Confucius and the Yellow Emperor.  

PubMed

Although Hippocrates (460-c.375 BC) has been traditionally recognized as the Father of Medicine, the fact that he was seminal in the development of cardiology is much less well known. Evidence is presented to support the notion that Hippocrates could also be considered the Father of Cardiology. Hippocrates also had many of the teachings and practices in common with Confucius (c.551-c.479 BC) and the Yellow Emperor of China (2695-2589 BC). Whereas Confucius was not a physician, the Yellow Emperor was an ancient Chinese physician whose Huang Di Neijing, the Yellow Emperor's Canon of Internal Medicine, is the oldest known treatise of medicine in existence. PMID:11744140

Cheng, T O

2001-12-01

336

Stress Annealing Induced Diffuse Scattering from Ni3 (Al, Si) Precipitates  

NASA Astrophysics Data System (ADS)

Diffuse scattering caused by L12 type Ni3 (Al, Si) precipitates after stress annealing of Ni-Al-Si alloys is studied. Peculiarities of diffuse scattering in the asymptotic region as compared to the Huang scattering region are discussed. Coupling between the stress annealing direction and the precipitate shape is demonstrated. Experimental reciprocal space maps (RSMs) are compared to theoretical ones. Oscillations of diffuse scattering due to Ni3 (Al, Sc) precipitates are observed. The strengths of the precipitates are estimated from the analysis of the diffuse scattering oscillations.

Barabash, R. I.; Ice, G. E.; Karapetrova, E. A.; Zschack, P.

2012-05-01

337

Double-to-single photoionization ratio of lithium at medium energies  

SciTech Connect

The double-to-single photoionization ratio of atomic lithium has been measured for photon energies ranging from 120 eV to 910 eV. Through extensive use of various filters we were able to significantly extend the previous range of measurements [M.-T. Huang et al., Phys. Rev. A 59, 3397 (1999)]. We find that our data are in agreement with the predicted high-energy limit of 3.4%. By applying simple model curves to our data, we believe that sequential processes contribute substantially to the double-photoionization cross-section ratio as predicted by theory.

Wehlitz, R.; Bluett, J.B. [Synchrotron Radiation Center, UW-Madison, Stoughton, Wisconsin 53589 (United States); Martinez, M.M. [University of Washington, Seattle, Washington 98105 (United States); Lukic, D. [Institute of Physics, 11001 Belgrade (Serbia and Montenegro); Whitfield, S.B. [Department of Physics and Astronomy, UW-Eau Claire, Eau Claire, Wisconsin 54702 (United States)

2004-06-01

338

Cyclometalated iridium(III) complexes containing hydroxide/chloride ligands: isolation of heterobridged dinuclear iridium(III) compounds containing ?-OH and ?-pyrazole ligands.  

PubMed

The reaction of the cyclometalated chloro-bridged iridium(III) dimers [(ppy)(2) Ir(?-Cl)](2) (ppyH = 2-phenyl pyridine) and [(tpy)(2)Ir(?-Cl)](2) (tpyH = 2-p-tolylpyridine) with 3,5-diphenylpyrazole (Ph(2)PzH) in the presence of sodium methoxide resulted in the formation of heterobridged dimers [(ppy)(2)Ir(?-OH)(?-Ph(2)Pz)Ir(ppy)(2)] (1) and [(tpy)(2)Ir(?-OH)(?-Ph(2)Pz)Ir(tpy)(2)] (2). Interestingly, the reaction of [(ppy)(2)Ir(?-Cl)](2) with 3(5)-methyl-5(3)-phenylpyrazole (PhMePzH) afforded both a heterobridged dimer, [(ppy)(2)Ir(?-OH)(?-PhMePz)Ir(ppy)(2)] (3), and the monomer [(ppy)(2)Ir(PhMePz)Cl] (4). The compound [(ppy)(2)Ir(PhMePz)OH] (5) containing a terminal OH was obtained in a hydrolysis reaction involving 4, sodium methoxide, and PhMePzH. Complexes 1-5 were characterized by X-ray crystallography and electrospray ionization high-resolution mass spectrometry. All of the complexes are luminescent at room temperature in their dichloromethane solutions. The luminescence of the dinuclear complexes is characterized by a single structureless band centered at ?(max) = 550 nm (1 and 3) and 546 nm (2). The emission spectra of the mononuclear complexes 4 and 5 display vibronic structures with their ?(max) values at 497 nm (4) and 513 nm (5). In each case, the main emission bands are accompanied by shoulder bands at 526 (4) and 534 nm (5). The quantum yields, calculated with reference to [Ir(ppy)(2)(bpy)]PF(6) (?(CH(3)CN) = 0.0622), range from 0.11 to 0.17 for the dinuclear complexes and 0.045 to 0.048 for the mononuclear complexes. The lifetimes of the emission are in the microsecond region, suggesting the phosphorescent nature of the emission. Density functional theory (DFT) and time-dependent DFT calculations were performed on complexes 1 and 4 in the ground state to gain insight into the structural, electronic, and photophysical properties. Electrochemical studies on complexes 1-3 showed the presence of two consecutive one-electron-oxidation processes, assigned as the stepwise oxidation of the two Ir(III) centers, i.e., Ir(III)-Ir(III)/Ir(III)-Ir(IV) and Ir(III)-Ir(IV)/Ir(IV)-Ir(IV) couples, respectively. The monomers displayed single-oxidation peaks. No reduction process was observed within the solvent cathodic potential limit. PMID:23013461

Chandrasekhar, Vadapalli; Mahanti, Bani; Bandipalli, Priyanka; Bhanuprakash, Kotamarthi

2012-09-26

339

Quantile regression for recurrent gap time data.  

PubMed

Evaluating covariate effects on gap times between successive recurrent events is of interest in many medical and public health studies. While most existing methods for recurrent gap time analysis focus on modeling the hazard function of gap times, a direct interpretation of the covariate effects on the gap times is not available through these methods. In this article, we consider quantile regression that can provide direct assessment of covariate effects on the quantiles of the gap time distribution. Following the spirit of the weighted risk-set method by Luo and Huang (2011, Statistics in Medicine 30, 301-311), we extend the martingale-based estimating equation method considered by Peng and Huang (2008, Journal of the American Statistical Association 103, 637-649) for univariate survival data to analyze recurrent gap time data. The proposed estimation procedure can be easily implemented in existing software for univariate censored quantile regression. Uniform consistency and weak convergence of the proposed estimators are established. Monte Carlo studies demonstrate the effectiveness of the proposed method. An application to data from the Danish Psychiatric Central Register is presented to illustrate the methods developed in this article. PMID:23489055

Luo, Xianghua; Huang, Chiung-Yu; Wang, Lan

2013-03-11

340

Ab initio molecular dynamics study of liquid Li surfaces exposed to deuterium  

NASA Astrophysics Data System (ADS)

We investigate the structure of liquid Li and its interactions with deuterium atoms using PROFESS (PRinceton Orbital-Free Electronic Structure Software) [1]. This linear-scaling orbital-free density functional theory method is a very fast quantum mechanics technique that allows one to perform ab initio molecular dynamics of metals for a large number of atoms and fairly long times. We adopt the WGC99 kinetic energy density functional that is very accurate for simple metals [2]. We use well validated bulk-derived local pseudopotentials [3] to describe the electron-ion interactions. Key properties of liquid Li will be presented and discussed, such as its bulk and surface structures, etc. Time permitting, we will discuss predictions related to adsorption and absorption of deuterium atoms into Li. This work provides new insights into understanding the surface structure of liquid Li using large-scale ab initio molecular dynamics methods. [1] L. Hung, C. Huang, I.Shin, G. Ho, V. L. Ligneres, and E. A. Carter, Comput. Phys. Comm., 181, 2208 (2010). [2] Y. A. Wang, N. Govind, and E. A. Carter, Phys. Rev. B, 60, 16350 (1999). Erratum: Phys. Rev. B, 64, 089903-1 (2001). [3] C. Huang and E. A. Carter, Phys. Chem. Chem. Phys., 10, 7109 (2008).

Chen, Mohan; Xia, Junchao; Shin, Ilgyou; Carter, Emily

2013-03-01

341

Algorithms and Results of Eye Tissues Differentiation Based on RF Ultrasound  

PubMed Central

Algorithms and software were developed for analysis of B-scan ultrasonic signals acquired from commercial diagnostic ultrasound system. The algorithms process raw ultrasonic signals in backscattered spectrum domain, which is obtained using two time-frequency methods: short-time Fourier and Hilbert-Huang transformations. The signals from selected regions of eye tissues are characterized by parameters: B-scan envelope amplitude, approximated spectral slope, approximated spectral intercept, mean instantaneous frequency, mean instantaneous bandwidth, and parameters of Nakagami distribution characterizing Hilbert-Huang transformation output. The backscattered ultrasound signal parameters characterizing intraocular and orbit tissues were processed by decision tree data mining algorithm. The pilot trial proved that applied methods are able to correctly classify signals from corpus vitreum blood, extraocular muscle, and orbit tissues. In 26 cases of ocular tissues classification, one error occurred, when tissues were classified into classes of corpus vitreum blood, extraocular muscle, and orbit tissue. In this pilot classification parameters of spectral intercept and Nakagami parameter for instantaneous frequencies distribution of the 1st intrinsic mode function were found specific for corpus vitreum blood, orbit and extraocular muscle tissues. We conclude that ultrasound data should be further collected in clinical database to establish background for decision support system for ocular tissue noninvasive differentiation.

Jurkonis, R.; Janusauskas, A.; Marozas, V.; Jegelevicius, D.; Daukantas, S.; Patasius, M.; Paunksnis, A.; Lukosevicius, A.

2012-01-01

342

Optimal Gaussian squeezed states for atom interferometry in the presence of phase diffusion  

SciTech Connect

We optimize the signal-to-noise ratio of a Mach-Zehnder atom interferometer with Gaussian squeezed input states in the presence interactions. For weak interactions, our results coincide with those of Huang and Moore [Y. P. Huang and M. G. Moore, Phys. Rev. Lett. 100, 250406 (2008)], with an optimal initial number variance {sigma}{sub o{proportional_to}}N{sup 1/3} and an optimal signal-to-noise ratio s{sub o{proportional_to}}N{sup 2/3} for the total atom number N. As the interaction strength u increases past unity, phase diffusion becomes dominant, leading to a transition in the optimal squeezing from initial number squeezing to initial phase squeezing with {sigma}{sub o{proportional_to}{radical}}(uN) and s{sub o{proportional_to}{radical}}(N/u) shot-noise scaling. The initial phase squeezing translates into hold-time number squeezing, which is less sensitive to interactions than coherent states and improves s{sub o} by a factor of {radical}(u).

Tikhonenkov, Igor [Department of Chemistry, Ben-Gurion University of the Negev, Post Office Box 653, Beer-Sheva 84105 (Israel); Moore, Michael G. [Department of Physics and Astronomy, Michigan State University, East Lansing, Michigan 48824 (United States); Vardi, Amichay [Department of Chemistry, Ben-Gurion University of the Negev, Post Office Box 653, Beer-Sheva 84105 (Israel); ITAMP, Harvard-Smithsonian CFA, 60 Garden Street, Cambridge, Massachusetts 02138 (United States)

2010-10-15

343

Can Medical Herbs Stimulate Regeneration or Neuroprotection and Treat Neuropathic Pain in Chemotherapy-Induced Peripheral Neuropathy?  

PubMed Central

Chemotherapy-induced neuropathy (CIPN) has a relevant impact on the quality of life of cancer patients. There are no curative conventional treatments, so further options have to be investigated. We conducted a systematic review in English and Chinese language databases to illuminate the role of medical herbs. 26 relevant studies on 5 single herbs, one extract, one receptor-agonist, and 8 combinations of herbs were identified focusing on the single herbs Acorus calamus rhizoma, Cannabis sativa fructus, Chamomilla matricaria, Ginkgo biloba, Salvia officinalis, Sweet bee venom, Fritillaria cirrhosae bulbus, and the herbal combinations Bu Yang Huan Wu, modified Bu Yang Huan Wu plus Liuwei Di Huang, modified Chai Hu Long Gu Mu Li Wan, Geranii herba plus Aconiti lateralis praeparata radix , Niu Che Sen Qi Wan (Goshajinkigan), Gui Zhi Jia Shu Fu Tang (Keishikajutsubuto), Huang Qi Wu Wu Tang (Ogikeishigomotsuto), and Shao Yao Gan Cao Tang (Shakuyakukanzoto). The knowledge of mechanism of action is still limited, the quality of clinical trials needs further improvement, and studies have not yielded enough evidence to establish a standard practice, but a lot of promising substances have been identified. While CIPN has multiple mechanisms of neuronal degeneration, a combination of herbs or substances might deal with multiple targets for the aim of neuroprotection or neuroregeneration in CIPN.

Schroder, Sven; Beckmann, Kathrin; Franconi, Giovanna; Greten, Henry Johannes; Rostock, Matthias; Efferth, Thomas

2013-01-01

344

Can medical herbs stimulate regeneration or neuroprotection and treat neuropathic pain in chemotherapy-induced peripheral neuropathy?  

PubMed

Chemotherapy-induced neuropathy (CIPN) has a relevant impact on the quality of life of cancer patients. There are no curative conventional treatments, so further options have to be investigated. We conducted a systematic review in English and Chinese language databases to illuminate the role of medical herbs. 26 relevant studies on 5 single herbs, one extract, one receptor-agonist, and 8 combinations of herbs were identified focusing on the single herbs Acorus calamus rhizoma, Cannabis sativa fructus, Chamomilla matricaria, Ginkgo biloba, Salvia officinalis, Sweet bee venom, Fritillaria cirrhosae bulbus, and the herbal combinations Bu Yang Huan Wu, modified Bu Yang Huan Wu plus Liuwei Di Huang, modified Chai Hu Long Gu Mu Li Wan, Geranii herba plus Aconiti lateralis praeparata radix , Niu Che Sen Qi Wan (Goshajinkigan), Gui Zhi Jia Shu Fu Tang (Keishikajutsubuto), Huang Qi Wu Wu Tang (Ogikeishigomotsuto), and Shao Yao Gan Cao Tang (Shakuyakukanzoto). The knowledge of mechanism of action is still limited, the quality of clinical trials needs further improvement, and studies have not yielded enough evidence to establish a standard practice, but a lot of promising substances have been identified. While CIPN has multiple mechanisms of neuronal degeneration, a combination of herbs or substances might deal with multiple targets for the aim of neuroprotection or neuroregeneration in CIPN. PMID:23983777

Schröder, Sven; Beckmann, Kathrin; Franconi, Giovanna; Meyer-Hamme, Gesa; Friedemann, Thomas; Greten, Henry Johannes; Rostock, Matthias; Efferth, Thomas

2013-07-31

345

Distribution of ligulid tapeworms in China.  

PubMed

A survey of ligulid tapeworms carried out from 1979 through 1985 covered 29 provinces and autonomous regions in China. Of the 25,800 fishes of 219 species that were dissected, fishes of 43 species were found to serve as second intermediate hosts. These tapeworms inflict heavy losses on freshwater commercial fisheries. Their distribution indicates 3 distinct major zones: the Qing Zang Gaoyuan is dominated by Ligula; the rest of China, with the exception of a crescent area in Guangdong Province bordering part of the southern coast down to Hainan Island, is dominated by Digramma; and a saddle-shaped corridor, north of 42 degrees N latitude, is characterized by a mix of both genera. Schizothoracinae are the primary hosts for Ligula, of which only Gymnocypris przewalskii przewalskii (Kessler) has economic value. Digramma is predominant in Carassius auratus auratus L. in reservoirs and lakes of 3 main water systems, Heilongjiang, Huang He (the Yellow River), and Chang Jiang (the Yangtze River), and in cultured cyprinids along the lower section of Huang He as well as in bodies of water on the Loess Plateau. Generic validity of ligulids and host specificity, their infection and periodicity, and control methods are discussed. PMID:3572664

Liao, X H; Liang, Z X

1987-02-01

346

Identifying Modes of Temperature Variability Using AIRS Data.  

NASA Astrophysics Data System (ADS)

We use the Atmospheric Infrared Sounder (AIRS) and Advance Microwave Sounding Unit (AMSU) data obtained on Aqua spacecraft to study mid-tropospheric temperature variability between 2002-2007. The analysis is focused on daily zonal means of the AIRS channel at 2388 1/cm in the CO2 R-branch and the AMSU channel #5 in the 57 GHz Oxygen band, both with weighting function peaking in the mid-troposphere (400 mb) and the matching sea surface temperature from NCEP (Aumann et al., 2007). Taking into account the nonlinear and non- stationary behavior of the temperature we apply the Empirical Mode Decomposition (Huang et al., 1998) to better separate modes of variability. All-sky (cloudy) and clear sky, day and night data are analyzed. In addition to the dominant annual variation, which is nonlinear and latitude dependent, we identified the modes with higher frequency and inter-annual modes. Some trends are visible and we apply stringent criteria to test their statistical significance. References: Aumann, H. H., D. T. Gregorich, S. E. Broberg, and D. A. Elliott, Geophys. Res. Lett., 34, L15813, doi:10.1029/2006GL029191, 2007. Huang, N. E. Z. Shen, S. R. Long, M. C. Wu, H. H. Shih, Q. Zheng, N.-C. Yen, C. C. Tung, and H. H. Liu, Proc. R. Soc. Lond., A 454, 903-995, 1998.

Ruzmaikin, A.; Aumann, H. H.; Yung, Y.

2007-12-01

347

Fully Ordered and Nano-Structured Inorganic-Organic Hybrid Semiconductors  

NASA Astrophysics Data System (ADS)

A family of novel inorganic-organic hybrid nanostructures based on II-VI semiconductors has been synthesized, including the first monolayer inorganic/organic superlattices with all covelent bonds (3D structures) and the smallest quantum wires (1D), the chains being formed of single II-VI atomic bonds [1]. These materials are atomistically reassembled crystals without the structural fluctuation typically found in other nanostrutures, and exhibit a number of remarkable properties (e.g., a giant bandgap tunability of 1-2 eV [1,2]). As a prototype system, a 3D structure ?-ZnTe(en)0.5 shows a strongly enhanced free exciton absorption (a few times of that in the II-VI binary), Raman lines as sharp as any binary semiconductor, band edge free exciton emission, and more than 10 times enhancement in the exciton binding energy. First-principles density function band structure calculations have been performed to obtain the band gap shift, dispersion relations (effective masses), and dielectric constants of the hybrid material, and the relevant band offsets. [1] X.-Y. Huang, J. Li, Y. Zhang, and A. Mascarenahs, JACS 125, 7049 (2003). [2] B. Fluegel, Y. Zhang, A. Mascarenahs, X.-Y. Huang, and J. Li, PRB 70, 205308 (2004).

Zhang, Yong; Huang, X.-Y.

2005-03-01

348

Bulk and Compound-Specific Isotope Analysis of Long-Chain, n-alkanes From a 85-kyr Core From Lake Peten Itza, Guatemala  

NASA Astrophysics Data System (ADS)

Drill cores obtained from Lake Petén Itzá, Guatemala, contain a ~85-kyr record of terrestrial climate from lowland Central America. Variations in sediment lithology suggest rapid changes in precipitation during the last glacial and deglacial periods. Previous work in nearby Lake Quexil demonstrated the utility of using the carbon isotopic compositions of leaf wax n-alkanes to infer changes in terrestrial vegetation (Huang et al., 2001). Here we report carbon isotopes of bulk organic and long-chain n-alkanes in 60 samples to reconstruct changes in the relative proportion of C3 and C4 biomass in the watershed under changing climate and atmospheric CO2 conditions during the past 85 kyrs. Compound-specific carbon isotope results are compared directly with pollen analysis from the same samples. Huang, Y., F.A. Street-Perrott, S.E. Metcalfe, M. Brenner, M. Moreland, and K.H. Freeman. 2001. Climate change as the dominant control on glacial-interglacial variations in C3 and C4 plant abundance. Science 293:1647-1651.

Mays, J. L.; Brenner, M.; Bush, M. B.; Correa, A.; Curtis, J. H.; Hodell, D. A.

2007-12-01

349

S-Wave Velocity Structure of the Puli Basin, Taiwan, Using the Array Records of Microtremors  

NASA Astrophysics Data System (ADS)

The September 21, 1999 Chi-Chi earthquake induced strong shaking, resulting in severe damage in the Puli area. According to Huang and Tarng (2005), the collapse of many structures during the earthquake was very closely related to the site effects. The Shallow Shear-wave velocities have widely been used for earthquake ground-motion site characterization. Thus, the S-wave velocity structures of the Puli area are investigated using the array records of microtremors at 16 sites. The dispersion curves at these sites are calculated using the F-K method (Capon, 1969); then, the S-wave velocity structures at the Puli area are estimated by employing the surface wave inversion technique (Herrmann, 1991). If the S-wave velocity of bedrock is assumed to be 2000m/sec, the depths of the alluvium at the Puli area are between 360m (ZHO) and 810m (AIL, DAH). Besides, there are 3~4 distinct interfaces in the shallow velocity structure (0~1000m). The depth of the alluvium gradually increases from east to west and the deepest one appears at stations AIL and DAH. The results in this study are similar to those using the seismic exploration method (Wang et al., 2003; Huang, 2008) in the Puli area and the well-logging method at LAC.

Wu, C.; Huang, H.

2009-12-01

350

ROCKing the JAKs  

PubMed Central

The endocrine cytokine leptin is mainly secreted by white adipose tissue and plasma leptin levels positively correlate with body fat mass. Via its action on neurons in the hypothalamic arcuate nucleus (ARC), leptin regulates body weight by stimulating energy expenditure and inhibiting food intake. The main signaling pathway of the leptin receptor is the JAK2-STAT3 pathway. A recent publication of Huang et al. in Nature Neuroscience shows that leptin’s hypothalamic signaling via JAK2 requires the kinase ROCK1 (Rho-associated coiled-coil-containing protein kinase 1). ROCK1 directly phosphorylates JAK2, and this phosphorylation is required for the JAK2-STAT3 pathway of the leptin receptor. Gene deletion of ROCK1 in ARC neurons targeted by leptin makes these neurons less sensitive to leptin. This is reflected by a pronounced weight gain with hyperphagia, reduced locomotor activity, and increased fat accumulation. In this article we comment on the article of Huang et al. While the mechanism of ROCK1 activation in the neurons remains uncharacterized for the moment, a literature survey suggests that the interplay between ROCK1 and a JAK kinase may be a common theme for receptors that function via a JAK2 and even for other members of the JAK kinase family.

Peelman, Frank; Tavernier, Jan

2013-01-01

351

Seed priming with chitosan improves maize germination and seedling growth in relation to physiological changes under low temperature stress*  

PubMed Central

Low temperature stress during germination and early seedling growth is an important constraint of global production of maize. The effects of seed priming with 0.25%, 0.50%, and 0.75% (w/v) chitosan solutions at 15 °C on the growth and physiological changes were investigated using two maize (Zea mays L.) inbred lines, HuangC (chilling-tolerant) and Mo17 (chilling-sensitive). While seed priming with chitosan had no significant effect on germination percentage under low temperature stress, it enhanced germination index, reduced the mean germination time (MGT), and increased shoot height, root length, and shoot and root dry weights in both maize lines. The decline of malondialdehyde (MDA) content and relative permeability of the plasma membrane and the increase of the concentrations of soluble sugars and proline, peroxidase (POD) activity, and catalase (CAT) activity were detected both in the chilling-sensitive and chilling-tolerant maize seedlings after priming with the three concentrations of chitosan. HuangC was less sensitive to responding to different concentrations of chitosan. Priming with 0.50% chitosan for about 60~64 h seemed to have the best effects. Thus, it suggests that seed priming with chitosan may improve the speed of germination of maize seed and benefit for seedling growth under low temperature stress.

Guan, Ya-jing; Hu, Jin; Wang, Xian-ju; Shao, Chen-xia

2009-01-01

352

Design concept for a Wedge-filter Imaging Sounder for Humidity (WISH): a practical NPOESS P3I high-spatial-resolution sensor  

NASA Astrophysics Data System (ADS)

Tropospheric wind is a top priority NPOESS EDR that can be retrieved by tracking high spatial resolution altitude-resolved water vapor sounding features in imagery provided by a humidity imaging sounder. A Wedge-filter Imaging Sounder (WIS) can provide the required humidity imagery and has already been studied for application in geostationary orbit by Puschell, Huang and Woolf. The Wedge-filter Imaging Sounder for Humidity (WISH) incorporates the same technology and is suitable for flight on the NPOESS C2 or C3 spacecraft. WISH would take advantage of payload capacity available for P3I demonstrations in NPOESS and would serve as a risk reduction and technology demonstration for future NOAA environmental satellite missions. In this paper, we present our analysis of a preliminary WISH sensor concept design, specification and expected radiometric sensitivity. The practicality of WISH for current NPOESS spacecraft configurations will also be discussed. The performance of WISH toward achieving NPOESS P3I's tropospheric wind objective will be discussed in a companion paper by Huang et al. in SPIE conference 5655.

Puschell, Jeffery J.; Huang, Hung-Lung A.; Bloom, Hal J.

2005-01-01

353

Single microwave photon source using circuit QED  

NASA Astrophysics Data System (ADS)

In circuit QED, a superconducting charge qubit is fabricated inside a high-quality factor transmission line resonator [1]. This opens the possibility to probe the regime of strong coupling of cavity QED using microwave photons and artificial atoms. This physics was experimentally investigated in the resonant [2] and in the dispersive [3] regime. In this talk, we will show how this setup could be used to generate single microwave photons on demand. Moreover, by using a different circuit QED layout with two resonators, photon generation could be tagged. The possibility to use a similar setup to detect single photons will also be discussed. [1] A. Blais, R.-S. Huang, A. Wallraff, S. M. Girvin and R. J. Schoelkopf, Phys. Rev. A 69, 062320 (2004). [2] A. Wallraff, D. Schuster, A. Blais, L. Frunzio, R.-S. Huang, J. Majer, S. Kumar, S. M. Girvin and R. J. Schoelkopf, Nature 431, 162 (2004). [3] D. I. Schuster, A. A. Houck, J. A. Schreier, A. Wallraff, J. M. Gambetta, A. Blais, L. Frunzio, B. Johnson, M. H. Devoret, S. M. Girvin and R. J. Schoelkopf, Cond-mat/0608693.

Blais, Alexandre; Gambetta, Jay; Cheung, Clifford; Wallraff, Andreas; Schuster, David; Girvin, Steven; Schoelkopf, Robert

2007-03-01

354

Neutron Scattering from Magnetically Frustrated Ruthenium Pyrochlores  

NASA Astrophysics Data System (ADS)

Spin-1 ruthenium pyrochlores feature strong exchange interactions and deeply suppressed N'eel ordering. In addition a doping induced metallic phase has been demonstrated. I discuss neutron scattering experiments that explore the strongly frustrated quantum magnetism of Y2Ru2O7 [1] and Pr2-xBixRu2O7 [2]. In Y2Ru2O7 (?CW= --1100 K, TN=77 K) much of the magnetic spectral weight is concentrated in a 20 meV spectral peak above an 11 meV low temperature gap in the excitation spectrum. In Pr2-xBixRu2O7 magnetic order which occurs for THuang, S.-W. Cheong, C. Broholm, and T. G. Perring, Submitted to Phys. Rev. B Rapid Communications, cond-mat 0707.2678v1 (2007). [2] J. van Duijn, K. H. Kim, N. Hur, D. Adroja, M. A. Adams, Q. Z. Huang, M. Jaime, S.-W. Cheong, C. Broholm, and T. G. Perring, Phys. Rev. Lett. 94, 177201 (2005).

Broholm, Collin

2008-03-01

355

Pulse-like rupture induced by three-dimensional fault zone flower structures  

NASA Astrophysics Data System (ADS)

Mature faults are often embedded in low-velocity fault zones (LVFZs). Numerical simulations of dynamic rupture including a LVFZ by Huang and Ampuero (2011) showed that if the wave velocity contrast between the LVFZ and the country rock is strong enough, ruptures can behave as pulse-like ruptures. The healing front that stops the rupture is generated by reflected waves from the LVFZ-country rock interface. However, the numerical study by Huang and Ampuero (2011) was limited to two-dimensional problems with fault-parallel fault zone structures. Natural fault zones include complexities such as flower structures with depth-dependent velocity and thickness, and limited depth extent. We will show here that the mechanism of pulse generation induced by the LVFZ also operates efficiently in such three-dimensional fault zone structures. This investigation requires high resolution and flexible mesh generation, which are enabled here by the high-order accurate ADER-DG method with an unstructured tetrahedral element discretization (Pelties et al., 2012). Our simulations show that the pulse generation mechanism is robust to the depth extent of the LVFZ and to the position of the hypocenter (whether it is inside or below the LVFZ). In particular, for events with hypocenter deeper than a shallow LVFZ, we find that a healing front emerges soon after the rupture enters the LVFZ, with rise time controlled by the LVFZ properties. Moreover, this healing front reflects from the free surface and propagates downdip beyond the bottom of the LVFZ, inducing there pulse-like rupture with longer rise time. Thus, we find that the depth-dependence of rise time might reflect the depth extent of the LVFZ. References: Huang, Y. and J.-P. Ampuero (2011), Pulse-like ruptures induced by low-velocity fault zones, J. Geophys. Res., 116, B12307, doi:10.1029/2011JB008684. Pelties, C., J. de la Puente, J.-Pl Ampuero, G. B. Brietzke, and M. Käser (2012), Three-Dimensional Dynamic Rupture Simulation with a High-order Discontinuous Galerkin Method on Unstructured Tetrahedral Meshes, J. Geophys. Res., 117, B02309, doi:10.1029/2011JB008857.

Pelties, Christian; Huang, Yihe; Ampuero, Jean-Paul

2013-04-01

356

Mid-Latitude Ionospheric Response to Storm Time Electric Field  

NASA Astrophysics Data System (ADS)

Huang et al. (private communication, 2004) have reported large increases, factors of 2-3, in the mid-latitude ionospheric electron density in the aftermath of a magnetic storm. The density increase was observed at two mid-latitude sites (Millstone Hill and Eglin), but was not seen at lower latitudes (Areceibo). Accompanying the increase was a decrease (of 800-1500 K) in the F-region electron temperature. We present simulations results from the NRL ionosphere models SAMI2 and SAMI3 of the response of the mid-latitude F-region ionosphere to an imposed electric field that simulates this magnetic storm. We obtain reasonable agreement with the observed density and temperature features despite a simple model of the storm electric field. Research supported by ONR.

Swisdak, M.; Joyce, G.; Huba, J.

2004-12-01

357

Microscopic wrinkles on supported surfactant monolayers  

NASA Astrophysics Data System (ADS)

We discuss mechanical buckling instabilities of a rigid film under compression interacting repulsively with a substrate through a thin fluid layer. The buckling occurs at a characteristic wavelength that increases as the one-fourth power of the bending stiffness, such as the gravitational instability studied previously by Milner However, the potential can affect the characteristic buckling wavelength strongly, as predicted by Huang and Suo. If the potential changes sufficiently sharply with thickness, this instability is continuous, with an amplitude varying as the square root of overpressure. We discuss three forms of interaction important for the case of Langmuir monolayers transferred to a substrate: Casimir-van der Waals interaction, screened charged double-layer interaction, and the Sharma potential. We verify these predictions numerically in the van der Waals case.

Zhang, Quan; Witten, T. A.

2007-10-01

358

Dielectric dispersion of clustered living cells via the boundary integral equation method  

NASA Astrophysics Data System (ADS)

We have developed a boundary integral equation (BIE) method for computing the dielectric response of clusters of biological particles like living cells. In the BIE, we formulate a surface integral equation for the scalar potential for an arbitrary number of particles of various shapes [1]. BIE method avoids matching the complicated boundary conditions on the surfaces of the particles. Numerical solutions of the eigenvalue equation yield a dielectric dispersion spectrum through the spectral representation [2]. While BIE method is valid for arbitrary surfaces, we confirm it for two approaching cylinders and a concentric cylinder. In many typical cases, the numerical results are in excellent agreement with the exact analytic results. Moreover, BIE method offers a convenient way to compute the alternating current responses, and hence the dielectric dispersion of clustered cell suspensions. [4pt] [1] Yu KW, Wan JTK, Computer Physics Communications 142, 368 (2001). [0pt] [2] Huang JP, Yu KW, Phys. Rep. 431, 87 (2006).

Kit Yung, Sai; Chan, Kin Lok; Yu, Kin Wah

2011-03-01

359

COMMITTEES: SQM2008-International Conference on Strangeness in Quark Matter SQM2008-International Conference on Strangeness in Quark Matter  

NASA Astrophysics Data System (ADS)

Local Organising Committee Xiangzhou Cai (SINPA) Weiqin Chao (CCAST) Liewen Chen (SJTU) Jianping Cheng (Tsinghua University) Jinghua Fu (CCNU) Yuanning Gao (Tsinghua University) Xiaomei Li (CIAE) Zuotang Liang (Shandong University) Feng Liu (CCNU), Co-chair Yuxin Liu (PKU) Qing Wang (Tsinghua University) Qun Wang (USTC) Hushan Xu (IMP) Daicui Zhou (CCNU) Pengfei Zhuang (Tsinghua University), Co-chair Bingsong Zou (IHEP) International Advisory Committee Jörg Aichelin, Nantes Federico Antinori, Padova Tamás Biró, Budapest Peter Braun-Munzinger, GSI Jean Cleymans, Cape Town László Csernai, Bergen Timothy Hallman, BNL Huan Zhong Huang, UCLA Takeshi Kodama, Rio de Janeiro Carlos Lourenço, CERN Yu-Gang Ma, Shanghai Jes Masden, Aarhus Yasuo Miake, Tsukuba Berndt Müller, Duke Grazyna Odyniec, LBNL Helmut Oeschler, Darmstadt Johann Rafelski, Arizona Hans Georg Ritter, LBNL Karel Šafa?ík, CERN Jack Sandweiss, Yale George S F Stephans, MIT Horst Stöcker, Frankfurt Thomas Ullrich, BNL Nu Xu, LBNL William A Zajc, Columbia

2008-04-01

360

Mapping of HtNB, a gene conferring non-lesion resistance before heading to Exserohilum turcicum (Pass.), in a maize inbred line derived from the Indonesian variety Bramadi.  

PubMed

The gene HtNB confers non-lesion resistance to the fungal pathogen Exserohilum turcicum in maize. To map this gene, we developed two F? populations, P111 (resistant line) x HuangZao 4 (susceptible line) and P111 x B73 (susceptible). HtNB was located on chromosome 8.07 bin, flanked by MAC216826-4 and umc2218 at distances of 3.3 and 3.4 cM, respectively. HtNB appears to be a new gene responsible for resistance to northern corn leaf blight. Functions of the genes in the region between umc1384 and umc2218 were predicted. In addition, several genes were found to be related to disease resistance, such as the genes encoding Ser/Thr protein kinase and protein-like leaf senescence. PMID:22869072

Wang, H; Xiao, Z X; Wang, F G; Xiao, Y N; Zhao, J R; Zheng, Y L; Qiu, F Z

2012-08-16

361

[Research of the EEMD method to pulse analysis of traditional Chinese medicine based on different amplitudes of the added white noise].  

PubMed

The ensemble empirical mode decomposition (EEMD) can be used to overcome the mode mixing problem of empirical mode decomposition (EMD) effectively. The EEMD method and Hilbert-Huang Transform (HHT) can be used to analyze pulse signals of Traditional Chinese Medicine (TCM). The amplitudes of the added white noise were about 0.1 and 0.2 time standard deviation of the investigated signal respectively. The difference of average frequency and average energy of every mode between normal pulse, slippery pulse, wiry pulse and wiry-slippery pulse were demonstrated based on different amplitudes of the added white noise. The results showed that it is more in line with clinical practice when the amplitude of the added white noise is about 0.2 time standard deviation of the investigated signal. PMID:21485176

Yan, Haixia; Qin, Kairong; Wang, Yiqin; Li, Fufeng; Run, Fengying; Hong, Yujian; Hao, Jiming

2011-02-01

362

Nonlinear data processing method for the signal enhancement of GPR data  

NASA Astrophysics Data System (ADS)

An alternative data processing procedure is proposed in this paper for the purpose of enhancing the signal/noise (S/N) ratio of ground penetrating radar (GPR) data. The processing methodology is achieved by performing the logarithmic transform in conjunction with the ensemble empirical mode decomposition (EEMD), a new nonlinear data analysis method in signal processing. The synthetic model study and field example indicate that the logarithmic transform is effective in alleviating the attenuation problem. Additionally, the spectrogram obtained from Hilbert-Huang transform (HHT) shows that the decomposition sensitivity of the EEMD method is greatly improved with the aid of the logarithmic transform. This new method allows us to extract the signal components from noisy GPR data efficiently. The success of this study suggests a possible nonlinear analysis application in future GPR investigation, particularly in the filter design and gain correction.

Chen, Chih-Sung; Jeng, Yih

2011-09-01

363

Synthesis of progesterone-11, 11, 12, 12-d/sub 4/  

SciTech Connect

A variant of the Huang-Minlon reduction of keto steroids was developed in this article. In it, the alpha-hydrogen atoms and the carbonyl oxygen were replaced by the corresponding numbers of deuterium atoms with the use of deuterium oxide as the sole primary source of the isotope. An investigation was made of the introduction of a 4,5-double bond into 5alpha-pregnane-3,20-dione by 2-bromination, the conversion of the product into the corresponding pyridinium salt, and its pyrolysis; the overall yield of progesterone was raised to 46%. With the use of the methods described, from gekogenin acetate the authors synthesized progesterone-11,11,12,12-d/sub 4/ of high isotopic purity, suitable for use as internal standard in chromato-mass-fragmentography.

Golubovskaya, L.E.; Pivnitskii, K.K.

1985-08-01

364

Comparison of mathematical models of lactic acid bacteria growth in vacuum-packaged raw beef stored at different temperatures.  

PubMed

The lactic acid bacteria grown in vacuum-packaged raw beef under 7, 10, 15, and 20?°C has been studied in this paper. Four primary models, the modified Gompertz, logistic, Baranyi, and Huang model were used for data fitting. Statistical criteria such as the bias factor and accuracy factor, mean square error, Akaike's information criterion, and the residual distribution were used for comparing the models. The result showed that all of the 4 models can fit the data well and they were not significantly different in the performance. They were equally capable of describing bacterial growth, but the growth rate and lag time estimated from the modified Gompertz model were a little higher than other models. The estimate for the lag time was not accurate as the growth rate. PMID:23560997

Li, M Y; Sun, X M; Zhao, G M; Huang, X Q; Zhang, J W; Tian, W; Zhang, Q H

2013-04-01

365

Time-frequency analysis of nonlinear and non-stationary weak signals of corona discharge  

NASA Astrophysics Data System (ADS)

It is very useful to study the signals radiated from corona discharges for the purposes of high-voltage line monitoring. Time-frequency analysis can clearly reveal the time-varying spectrum characteristics of such signals, which is very useful for analyzing and processing the non-linear and non-stationary weak signals, such as the signals radiated from corona discharges. Several time-frequency analysis methods, such as the Short-Time Fourier Transform (STFT), Wigner-Ville distribution and the Hilbert-Huang Transform (HHT) and so on, are used in this paper. The simulation data with the same and different amplitudes are comparatively analyzed by these time-frequency distribution methods. It can be concluded that the time-frequency analysis method based on HHT is more efficient to identify and suitable for the non-linear and non-stationary weak signals.

Wang, Lei; Liu, Shanghe; Wei, Ming; Hu, Xiao Feng

2013-03-01

366

Optical properties of the hybrid nanocomposites consisting of poly- n-phenylvinylene and cadmium sulfide  

NASA Astrophysics Data System (ADS)

Thin-film hybrid nanocomposites based on poly- n-phenylvinylene with various contents of the CdS semiconductor nanoparticles are obtained using the pyrolytic polymerization of dichloro- n-xylene from the gas phase and the simultaneous sedimentation of the CdS vapor with the subsequent thermal processing of the precursor. The structure of the nanocomposite is studied, and the optical properties of the materials are analyzed. It is demonstrated that a variation in the concentration of the inorganic component in the polymer matrix leads to a variation in the maximum fluorescence wavelength and optical band gap. The material parameters (degree of conjugation of poly- n-phenylvinylene, band gap, Huang-Rhys factor, Stokes shift, and vibronic energy of molecules) are determined.

Morozov, P. V.; Grigor'ev, E. I.; Zav'yalov, S. A.; Klimenko, V. G.; Nesmelov, A. A.; Vdovichenko, A. Yu.; Chvalun, S. N.

2013-03-01

367

ELECTROMAGNETISM, OPTICS, ACOUSTICS, HEAT TRANSFER, CLASSICAL MECHANICS, AND FLUID DYNAMICS: Symmetry Analysis of Barotropic Potential Vorticity Equation  

NASA Astrophysics Data System (ADS)

Recently F. Huang [Commun. Theor. Phys. 42 (2004) 903] and X. Tang and P.K. Shukla [Commun. Theor. Phys. 49 (2008) 229] investigated symmetry properties of the barotropic potential vorticity equation without forcing and dissipation on the beta-plane. This equation is governed by two dimensionless parameters, F and ?, representing the ratio of the characteristic length scale to the Rossby radius of deformation and the variation of earth' angular rotation, respectively. In the present paper it is shown that in the case F ? 0 there exists a well-defined point transformation to set ? = 0. The classification of one- and two-dimensional Lie subalgebras of the Lie symmetry algebra of the potential vorticity equation is given for the parameter combination F ? 0 and ? = 0. Based upon this classification, distinct classes of group-invariant solutions are obtained and extended to the case ? ? 0.

Bihlo, Alexander; Popovych, Roman O.

2009-10-01

368

Graduating Underrepresented African American, Latino, and American Indian Students in Science  

NASA Astrophysics Data System (ADS)

African American, Latino, and American Indian students are less likely to graduate in science than comparable White and Asian students (Gándara & Maxwell-Jolly, 1999; Huang, Taddese, & Walter, 2000). After controlling for preparation and need (p < .05), logistic regression modeling of data from the University of Colorado, Boulder, confirmed this. However, students in the University of Colorado Minority Arts and Sciences Program (MASP) were more likely to graduate in science than White and Asian students (p < .05). MASP students valued the program's financial support, academic community, and relationships with professors, but not, notably, academic enrichment workshops. This finding provides insight into factors that increase retention of well prepared African American, Latino, and American Indian students and calls for further research and theory.

Johnson, Angela

369

Superconvergence of bi-k-Lagrange elements for eigenvalue problems  

NASA Astrophysics Data System (ADS)

We study superconvergence of bi-k-Lagrange elements for parameter-dependent problems where k?2. We show that the superconvergence rate of the bi-k-Lagrange elements is two orders higher than that of the kth-order Lagrange elements. This is a significant improvement of the previous results [C.-S. Chien, H.T. Huang, B.-W. Jeng, Z.C. Li, Superconvergence of FEMs and numerical continuation for parameter-dependent problems with folds, Int. J. Bifurcation Chaos 18 (2008) 1321-1336], which is only one order (or a half order) higher than that of the latter. Next, we apply the bi-k-Lagrange elements to the computations of energy levels and wave functions of two-dimensional (2D) Bose-Einstein condensates (BEC), and BEC in a periodic potential. Sample numerical results are reported.

Li, Z.-C.; Chien, C.-S.; Huang, H.-T.; Jeng, B.-W.

2009-11-01

370

Temperature-dependent photoluminescence properties of MnF2: Configurational-coordinate model analysis  

NASA Astrophysics Data System (ADS)

A white MnF2 powder is synthesized by chemical etching of Mn shots in an aqueous HF solution. The optical properties of this synthesized powder are investigated using photoluminescence (PL) analysis, PL excitation spectroscopy, diffuse reflectivity, and PL decay measurements. The MnF2 powder exhibits PL peaks in the red (~600 nm) and infrared spectral regions (~780 nm) under visible to ultraviolet excitation. These PL peaks are asymmetric with a tail on the long-wavelength side. Such spectral features and temperature-dependent PL intensities are well interpreted by a newly developed model with Huang-Rhys's factor as the electron-local vibration coupling strength. The ground- and excited-state energy level diagram for the Mn2+ ions in MnF2 is also proposed.

Arai, Takahiro; Adachi, Sadao

2011-05-01

371

Field measurement of upper ocean turbulence dissipation associated with wave-turbulence interaction in the South China Sea  

NASA Astrophysics Data System (ADS)

The turbulence dissipation rate within the mixed layer was measured in the open ocean and the coastal water of the South China Sea under moderate winds of 4.7 ˜ 8.9 m s-1 using a free-falling MSS profiler. In the open ocean, the profile of the dissipation rate within the mixed layer exhibited an exponential decay with the depth at most stations, which was satisfactorily consistent with that predicted by the parameterization of wave-turbulence interaction presented by Huang and Qiao (2010) while deviating from that by the law of the wall. In the coastal ocean, however, both the parameterization of wave-turbulence interaction and the law of the wall can give approximate predictions to the measured dissipation rate.

Huang, Chuan Jiang; Qiao, Fangli; Dai, Dejun; Ma, Hongyu; Guo, Jingsong

2012-11-01

372

Simulation and signal processing of through wall UWB radar for human being's periodic motions detection  

NASA Astrophysics Data System (ADS)

The human's Micro-Doppler signatures resulting from breathing, arm, foot and other periodic motion can provide valuable information about the structure of the moving parts and may be used for identification and classification purposes. In this paper, we carry out simulate with FDTD method and through wall experiment with UWB radar for human being's periodic motion detection. In addition, Advancements signal processing methods are presented to classify and to extract the human's periodic motion characteristic information, such as Micro-Doppler shift and motion frequency. Firstly, we apply the Principal Component Analysis (PCA) with singular value decomposition (SVD) to denoise and extract the human motion signal. Then, we present the results base on the Hilbert-Huang transform (HHT) and the S transform to classify and to identify the human's micro-Doppler shift characteristics. The results demonstrate that the combination of UWB radar and various processing methods has potential to detect human's Doppler signatures effectively.

Li, Jing; Liu, Fengshan; Xu, Penglong; Zeng, Zhaofa

2013-05-01

373

Aggregate colour centres in impurity LiF crystals  

SciTech Connect

LiF crystals with colour centres exhibiting a zero-phonon line (ZPL) at 1080 nm in absorption and luminescence are studied. The decay time of luminescence of colour centres at 10 K is 260 - 280 ns, the ZPL half-width is 4.7 cm{sup -1}, and colour centres are characterised by a weak electron - phonon interaction (the Huang - Rhys factor is S < 0.11). The polarisation analysis of luminescence showed that the transition dipole moments of colour centres are oriented along the crystal axes [100], [010], and [001]. The model of aggregate F{sub 4} colour centres having a spatial structure with three symmetry axes C{sub 2} may correspond to the colour centres studied in the paper. (active media. lasers)

Basiev, Tasoltan T; Karasik, Aleksandr Ya; Konyushkin, V A; Papashvili, A G; Pukhov, K K [Laser Materials and Technology Research Center, A. M. Prokhorov General Physics Institute, Russian Academy of Sciences, Moscow (Russian Federation); Ermakov, I V; Gellermann, V [Department of Physics, University of Utah (United States)

2002-08-31

374

Born-Oppenheimer approximation for open quantum systems within the quantum trajectory approach  

SciTech Connect

Using the quantum trajectory approach, we extend the Born-Oppenheimer (BO) approximation from closed to open quantum systems, where the open quantum system is described by a master equation in Lindblad form. The BO approximation is defined and the validity condition is derived. We find that the dissipation in fast variables improves the BO approximation, unlike the dissipation in slow variables. A detailed comparison is presented between this extension and our previous approximation based on the effective Hamiltonian approach [X. L. Huang and X. X. Yi, Phys. Rev. A 80, 032108 (2009)]. Several additional features and advantages are analyzed, which show that the two approximations are complementary to each other. Two examples are described to illustrate our method.

Huang, X. L.; Wu, S. L.; Wang, L. C.; Yi, X. X. [School of Physics and Optoelectronic Technology, Dalian University of Technology, Dalian 116024 (China)

2010-05-15

375

Stability and clustering of self-similar solutions of aggregation equations  

NASA Astrophysics Data System (ADS)

In this paper we consider the linear stability of a family of exact collapsing similarity solutions to the aggregation equation ?t = ? . (??K * ?) in Rd, d >= 2, where K(r) = r?/? with ? > 2. It was previously observed [Y. Huang and A. L. Bertozzi, ``Self-similar blowup solutions to an aggregation equation in Rn,'' J. SIAM Appl. Math. 70, 2582-2603 (2010)] that radially symmetric solutions are attracted to a self-similar collapsing shell profile in infinite time for ? > 2. In this paper we compute the stability of the similarity solution and show that the collapsing shell solution is stable for 2 < ? < 4. For ? > 4, we show that the shell solution is always unstable and destabilizes into clusters that form a simplex which we observe to be the long time attractor. We then classify the stability of these simplex solutions and prove that two-dimensional (in-)stability implies n-dimensional (in-)stability.

Sun, Hui; Uminsky, David; Bertozzi, Andrea L.

2012-11-01

376

Simultaneous ionization and excitation of helium by electron impact  

NASA Astrophysics Data System (ADS)

We present numerical results for He (1s2) (e, 2e) He+ reaction process for transitions to the n = 1, 2 and 3 states of He+ for noncoplanar symmetric geometry at incident energies of 1000 and 1600 eV. The calculations are performed using the plane wave impulse approximation (PWIA) and the 3C method (also called the Brauner, Briggs and Klar (BBK) model) that includes post collision interaction and multiple scattering effects. In both the methods we have used the highly correlated configuration interaction wave function for the ground state of helium. A comparison of the present theoretical cross sections with the recent measured data of Ren et al. [X.G. Ren, C.G. Ning, J.K. Deng, G.L. Su, S.F. Zhang, Y.R. Huang, G.Q. Li, Phys. Rev. A 72 (2005) 042718] shows reasonably good agreement.

Dal Cappello, C.; Roy, A. C.; Ren, X. G.; Dey, R.

2008-02-01

377

Crack detection using nonlinear acoustics and piezoceramic transducers—instantaneous amplitude and frequency analysis  

NASA Astrophysics Data System (ADS)

This paper investigates the nonlinear vibro-acoustic modulation technique for damage detection in metallic structures. Surface-bonded, low-profile piezoceramic actuators are used to introduce a high-frequency ultrasonic wave and low-frequency modal vibration into an aluminium specimen. The response of the vibro-acoustic interaction is monitored by a third low-profile piezoceramic transducer. In contrast to previous applications analysing the response in the frequency domain, current investigations focus on the instantaneous characteristics of the response using the Hilbert-Huang transform. The study shows that both modulations, i.e. amplitude and frequency, are present in the acoustical responses when the aluminium plate is cracked. The intensity of amplitude modulation correlates far better with crack lengths than the intensity of frequency modulations.

Hu, H. F.; Staszewski, W. J.; Hu, N. Q.; Jenal, R. B.; Qin, G. J.

2010-06-01

378

Periodicity in the most violent solar eruptions: recent observations of coronal mass ejections and flares revisited  

NASA Astrophysics Data System (ADS)

Using the Hilbert-Huang Transform method, we investigate the periodicity in the monthly occurrence numbers and monthly mean energy of coronal mass ejections (CMEs) observed by the Large Angle and Spectrometric Coronagraph Experiment on board the Solar and Heliographic Observatory from 1999 March to 2009 December. We also investigate the periodicity in the monthly occurrence numbers of H? flares and monthly mean flare indices from 1996 January to 2008 December. The results show the following. (1) The period of 5.66 yr is found to be statistically significant in the monthly occurrence numbers of CMEs; the period of 10.5 yr is found to be statistically significant in the monthly mean energy of CMEs. (2) The periods of 3.05 and 8.70yr are found to be statistically significant in the monthly occurrence numbers of H? flares; the period of 9.14yr is found to be statistically significant in the monthly mean flare indices.

Gao, Peng-Xin; Xie, Jing-Lan; Liang, Hong-Fei

2012-03-01

379

Linking typhoon tracks with rainfall patterns and flood timing  

NASA Astrophysics Data System (ADS)

Being able to predict the timing and amount of flooding during and following a hurricane or typhoon would improve early warning and mitigation efforts. However, variable typhoon tracks and interaction between typhoons and varied landscapes make flood prediction challenging. Huang et al. investigated the detailed distribution of typhoon-induced rainfall over a mesoscale mountainous watershed located in eastern Taiwan, a region that is regularly affected by severe typhoons—losses associated with typhoons in Taiwan can reach $500 million per year. The researchers analyzed high-resolution radar observations of 38 rainfall events during 2000-2010 in eastern Taiwan to study the relationship between typhoon track, rainfall patterns, and the timing of peak flooding.

Balcerak, Ernie

2012-11-01

380

Comment on 'multifractal diffusion entropy analysis on stock volatility in financial markets' [Physica A 391 (2012) 5739-5745  

NASA Astrophysics Data System (ADS)

In their recent article 'multifractal diffusion entropy analysis on stock volatility in financial markets' Huang, Shang and Zhao (2012) [6] suggested a generalization of the diffusion entropy analysis method with the main goal of being able to reveal scaling exponents for multifractal times series. The main idea seems to be replacing the Shannon entropy by the Rényi entropy, which is a one-parametric family of entropies. The authors claim that based on their method they are able to separate long range and short correlations of financial market multifractal time series. In this comment I show that the suggested new method does not bring much valuable information in obtaining the correct scaling for a multifractal/mono-fractal process beyond the original diffusion entropy analysis method. I also argue that the mathematical properties of the multifractal diffusion entropy analysis should be carefully explored to avoid possible numerical artefacts when implementing the method in analysis of real sequences of data.

Morozov, A. Yu.

2013-05-01

381

GaN nanorods grown on Si (111) substrates and exciton localization  

PubMed Central

We have investigated exciton localization in binary GaN nanorods using micro- and time-resolved photoluminescence measurements. The temperature dependence of the photoluminescence has been measured, and several phonon replicas have been observed at the lower energy side of the exciton bound to basal stacking faults (I1). By analyzing the Huang-Rhys parameters as a function of temperature, deduced from the phonon replica intensities, we have found that the excitons are strongly localized in the lower energy tails. The lifetimes of the I1 and I2 transitions were measured to be < 100 ps due to enhanced surface recombination. PACS: 78.47.+p, 78.55.-m, 78.55.Cr, 78.66.-w, 78.66.Fd

2011-01-01

382

a Simplified Parameter Design Method for Transformation Optics-Based Metamaterial Innovative Cloak  

NASA Astrophysics Data System (ADS)

Transformation optics-based innovative cloak which combines the virtues of both internal and external cloaks to enable arbitrary multi-objects hidden with visions and movements was first proposed by Huang et al. [Appl. Phys. Lett.101, 151901 (2012)]. But it is rather difficult to implement in practice, for the required material parameters vary with radius and even have singular values. To accelerate its practical realization but still keep good performance of invisibility, a simplified innovative cloak with only spatially varying axial parameter is developed via choosing appropriate transformation function. The advantage of such a cloak is that both radial and azimuthal parameters are constants, and all three components are nonsingular and finite. Full-wave simulation confirms the perfect cloaking effect of the cloak. Besides, the influences of metamaterials loss and parameter deviation on the performance of cloak are also investigated. This work provides a simple and feasible solution to push metamaterial-assisted innovative cloak more closely to the practice.

Li, Ting-Hua; Huang, Ming; Yang, Jing-Jing; Lu, Jin; Cao, Hui-Lu

2013-10-01

383

Temperature-responsive Turbidity Change of Semi-Interpenetrating Polymer Gel  

NASA Astrophysics Data System (ADS)

Temperature-responsive Turbidity Change of Semi-Interpenetrating Polymer Gel Gang Huang, Jun Gao, Zhibing Hu Department of Physics, University of North Texas ABSTRACT Poly(N-isopropylacrylamide) (PNIPA) is a well-known thermo-sensitive polymer with its lower critical solution temperature(LCST) in water at about 32°C. With the induction of sodium chloride, the LCST of PNIPA could be greatly shifted to the lower temperature. Due to the volume phase transition, the turbidity of PNIPA chain solution could change sharply and reversibly. The peculiar property of the volume phase transition can be applied to the display or the thermo-controlled optical windows, when PNIPA chain was incorporated into a hydrogel matrix. Such display device has many potential advantages and applications.

Huang, Gang; Gao, Jun; Hu, Zhibing

2000-10-01

384

Dipolar Bose-Einstein condensates in weak anisotropic disorder  

NASA Astrophysics Data System (ADS)

Here we study properties of a homogeneous dipolar Bose-Einstein condensate in a weak anisotropic random potential with Lorentzian correlation at zero temperature. To this end we solve perturbatively the Gross-Pitaevskii equation to second order in the random potential strength and obtain analytic results for the disorder ensemble averages of both the condensate and the superfluid depletion, the equation of state, and the sound velocity. For a pure contact interaction and a vanishing correlation length, we reproduce the seminal results of Huang and Meng, which were originally derived within a Bogoliubov theory around a disorder-averaged background field. For dipolar interaction and isotropic Lorentzian-correlated disorder, we obtain results which are qualitatively similar to the case of an isotropic Gaussian-correlated disorder. In the case of an anisotropic disorder, the physical observables show characteristic anisotropies which arise from the formation of fragmented dipolar condensates in the local minima of the disorder potential.

Nikoli?, Branko; Balaž, Antun; Pelster, Axel

2013-07-01

385

Elastic properties of amorphous Si and derived Debye temperatures and Grueneisen parameters: Model calculation  

SciTech Connect

Calculations, based on the Stillinger-Weber (SW) interatomic-potential model and the method of long waves, are presented for the elastic properties of amorphous Si ({ital a}-Si) and for pressure derivatives of the elastic constants of crystalline Si. Several models of {ital a}-Si, relaxed on the basis of the SW potential, are considered, and the external stresses that are associated with these models are evaluated using the Born-Huang relations. The elastic constants appear to obey the isotropy conditions to within a reasonable accuracy and are also consistent with other predictions based on the SW potential at finite temperature obtained by Kluge and Ray. Estimates of the pressure dependence of the elastic constants, Debye temperature, and Grueeisen parameter for {ital a}-Si are also provided on the basis of these calculations.

Feldman, J.L.; Broughton, J.Q. (Complex Systems Theory Branch, Naval Research Laboratory, Washington, D.C. 20375-5000 (US)); Wooten, F. (Department of Applied Science, University of California at Davis/Livermore, Livermore, California 94550 (US))

1991-01-15

386

Elastic properties of amorphous Si and derived Debye temperatures and Grüneisen parameters: Model calculation  

NASA Astrophysics Data System (ADS)

Calculations, based on the Stillinger-Weber (SW) interatomic-potential model and the method of long waves, are presented for the elastic properties of amorphous Si (a-Si) and for pressure derivatives of the elastic constants of crystalline Si. Several models of a-Si, relaxed on the basis of the SW potential, are considered, and the external stresses that are associated with these models are evaluated using the Born-Huang relations. The elastic constants appear to obey the isotropy conditions to within a reasonable accuracy and are also consistent with other predictions based on the SW potential at finite temperature obtained by Kluge and Ray. Estimates of the pressure dependence of the elastic constants, Debye temperature, and Grüeisen parameter for a-Si are also provided on the basis of these calculations.

Feldman, J. L.; Broughton, J. Q.; Wooten, F.

1991-01-01

387

On the Complex Nature of Magnetic Field Fluctuations During Geomagnetic Tail Current Disruption  

NASA Astrophysics Data System (ADS)

One of the phenomena occurring at the onset of magnetospheric substorms is the disruption of the cross-tail current. In the course of the years, this phenomenon has been clearly shown to be characterized by a large spectrum of fluctuations occurring over a large scale interval. Here, the multiscale nature and the complex features of the cross-coupling between the different scales is investigated in the case of an already studied magnetotail current disruption event, observed by a THEMIS satellite on 29 January 2008, by means of the Hilbert-Huang Transform (HHT) and an information theory approach. A particular attention is devoted to the presence of a dual cascading process: an inverse cascading process in the MHD domain (already suggested in several works) and a direct cascading process toward non-MHD scales.

Consolini, G.; De Michelis, P.; Tozzi, R.

2011-12-01

388

COMMITTEES: SQM 2007 - International Conference On Strangeness In Quark Matter SQM 2007 - International Conference On Strangeness In Quark Matter  

NASA Astrophysics Data System (ADS)

Local Organising Committee Ivan Králik (IEP SAS, Košice) Vojt?ch Petrá?ek (Czechoslovakia Technical University, Prague) Ján Pišút (Comenius University, Bratislava) Emanuele Quercigh (CERN) Karel Šafa?ík (CERN), Co-chair Ladislav v Sándor (IEP SAS, Košice), Co-chair Boris Tomášik (Mateja Bela University, Banská Bystrica) Jozef Urbán (UPJŠ Košice) International Advisory Committee Jörg Aichelin, Nantes Federico Antinori, Padova Tamás Biró, Budapest Peter Braun-Munzinger, GSI Jean Cleymans, Cape Town László Csernai, Bergen Timothy Hallman, BNL Huan Zhong Huang, UCLA Sonja Kabana, Nantes Roy A Lacey, Stony Brook Carlos Lourenço, CERN Yu-Gang Ma, Shanghai Jes Masden, Aarhus Yasuo Miake, Tsukuba Berndt Müller, Duke Grazyna Odyniec, LBNL Helmut Oeschler, Darmstadt Jan Rafelski, Arizona Hans Georg Ritter, LBNL Jack Sandweiss, Yale George S F Stephans, MIT Horst Stöcker, Frankfurt Thomas Ullrich, BNL Orlando Villalobos-Baillie, Birmingham William A Zajc, Columbia

2008-04-01

389

ART: a next-generation sequencing read simulator  

PubMed Central

Summary: ART is a set of simulation tools that generate synthetic next-generation sequencing reads. This functionality is essential for testing and benchmarking tools for next-generation sequencing data analysis including read alignment, de novo assembly and genetic variation discovery. ART generates simulated sequencing reads by emulating the sequencing process with built-in, technology-specific read error models and base quality value profiles parameterized empirically in large sequencing datasets. We currently support all three major commercial next-generation sequencing platforms: Roche's 454, Illumina's Solexa and Applied Biosystems' SOLiD. ART also allows the flexibility to use customized read error model parameters and quality profiles. Availability: Both source and binary software packages are available at http://www.niehs.nih.gov/research/resources/software/art Contact: weichun.huang@nih.gov; gabor.marth@bc.edu Supplementary information: Supplementary data are available at Bioinformatics online.

Huang, Weichun; Li, Leping; Myers, Jason R.; Marth, Gabor T.

2012-01-01

390

Critical particle size for fractionation by deterministic lateral displacement.  

PubMed

The fractionation of small particles in a liquid based on their size in a micropost array by deterministic lateral displacement was recently demonstrated with unprecedented resolution (L. R. Huang, E. C. Cox, R. H. Austin and J. C. Sturm, Science, 2004, 304, 987-990, ). In this paper, we present a model of how the critical particle size for fractionation depends on the micropost geometry, depending specifically on the gap between posts, the offset of posts in one row with respect to another, and whether the fluid is driven by hydrodynamics or by electroosmosis. In general the critical particle diameter is much smaller than the gap, which prevents clogging. The model is supported by data with particles from 2.3 to 22 microm. PMID:16652181

Inglis, David W; Davis, John A; Austin, Robert H; Sturm, James C

2006-03-17

391

Shallow water marine gammaridean amphipods of Pulau Tioman, Malaysia, with the description of a new species  

PubMed Central

Abstract Eleven taxa including one new species of gammaridean amphipods are reported from the waters of Pulau Tioman. The presence of Tethygeneia sunda sp. n. represents the first record of the genus from the South China Sea. Additional material of Ampelisca brevicornis (Costa, 1853); Cymadusa vadosa Imbach, 1967; Paradexamine setigera Hirayama, 1984; Ericthonius pugnax (Dana, 1853); Leucothoe furina (Savigny, 1816); Microlysias xenokeras (Stebbing, 1918); Monoculodes muwoni Jo, 1990 are identified from the South China Sea, supporting previous records by Lowry (2000), Huang (1994), Imbach (1967), Margulis (1968) and Nagata (1959). Three additional species, Gitanopsis pusilla K.H. Barnard, 1916, Liljeborgia japonica Nagata, 1965b and Latigammaropsis atlantica (Stebbing, 1888), whilst previously reported from the neighbouring waters, comprise new records for the South China Sea.

Azman, B.A.R.; Othman, B.H.R.

2013-01-01

392

Mean-field theory for ferroelectricity in Ca3CoMnO6  

SciTech Connect

An elastic Ising model for CoMnO6 chain is proposed to explain the ferroelectricity induced by collinear magnetic order in Ca3CoMnO6, and then a mean-field theory with interchain spin interactions based on this model is developed. With inclusion of the dynamics of polarization domains at finite temperature, we address the rationality of our theory by the good agreement of the calculated electric polarization and dielectric susceptibility with the reported data on Ca3Co2 xMnxO6 x 0.96 Y. J. Choi, H. T. Yi, S. Lee, Q. Huang, V. Kiryukhin, and S.-W. Cheong, Phys. Rev. Lett. 100, 047601 2008 , a typical diatomic Ising spin chain system, while the predicted magnetic susceptibility shows some difference from experiment, the reason of which is discussed.

Guo, Y. J. [Nanjing National Laboratory of Microstructures, Nanjing University, Nanjing; Dong, Shuai [ORNL; Wang, Kefeng [Nanjing National Laboratory of Microstructures, Nanjing University, Nanjing; Liu, J.-M. [Nanjing National Laboratory of Microstructures, Nanjing University, Nanjing

2009-01-01

393

Analysis of MHD harmonic modes from the novel tangential X-ray diagnostic in EAST tokamak  

NASA Astrophysics Data System (ADS)

The magnetohydrodynamics (MHD) harmonic modes as well as the underlying physics have been investigated in detail by applications of the Hilbert-Huang transform (HHT), higher-order spectrum (HOS) analysis and Fourier transform (FT), based on the novel tangential X-ray (TX) diagnostic (Li E. et al., Rev. Sci. Instrum., 81 (2010) 106102). Those signal process methods were applied to a rotating m/n=2/1 magnetic island, and it was found that its second-order harmonic m/n=4/2 appearing in FT spectrum (m, n are poloidal and toroidal mode numbers, respectively) was not an intrinsic mode, but a measure of distortion of the saturated magnetic island m/n=2/1.

Li, Erzhong; Hu, Liqun

2011-04-01

394

Non-ideal boson system in the Gaussian approximation  

SciTech Connect

We investigate ground-state and thermal properties of a system of non-relativistic bosons interacting through repulsive, two-body interactions in a self-consistent Gaussian mean-field approximation which consists in writing the variationally determined density operator as the most general Gaussian functional of the quantized field operators. Finite temperature results are obtained in a grand canonical framework. Contact is made with the results of Lee, Yang, and Huang in terms of particular truncations of the Gaussian approximation. The full Gaussian approximation supports a free phase or a thermodynamically unstable phase when contact forces and a standard renormalization scheme are used. When applied to a Hamiltonian with zero range forces interpreted as an effective theory with a high momentum cutoff, the full Gaussian approximation generates a quasi-particle spectrum having an energy gap, in conflict with perturbation theory results. {copyright} 1997 Academic Press, Inc.

Tommasini, P.R. [Institute for Theoretical Atomic and Molecular Physics, Harvard-Smithsonian Center for Astrophysics, Cambridge, Massachusetts 02138 (United States); de Toledo Piza, A.F. [Instituto de Fisica, Universidade de Sao Paulo, C.P. 66318, 05389-970 Sao Paulo, SP, (Brasil)

1997-01-01

395

Heat transfer due to axial turbulent flow along a circular rod  

NASA Astrophysics Data System (ADS)

A numerical study of heat transfer due to turbulent flow along a vertical circular pin was performed using the eddy viscosity formulation for forced convection flow developed by Cebeci and Smith (1974) and the numerical procedure for solving the boundary-layer equations of Huang and Chen (1984). The results indicate that overall heat transfer rate of the pin in the turbulent flow is higher than that of the pin in the laminar flow, and the temperature distributions of the pin in the turbulent flow give a larger variation than those of the pin in the laminar flow. This behavior is attributed to enhanced surface that-transfer rate associated with an increase in the random spots of turbulence along the streamwise direction.

Chen, C.-K.; Cleaver, J. W.; Lien, F.-S.

1986-01-01

396

[Pharmacological research on Chinese materia medica in Modern China and TCM].  

PubMed

The experimental pharmacological research on Ma-Huang and Tang-Kuei (Danggui) by Chen Kokuei and his colleagues in 1923, is the proem of scientific research on Chinese materia medica (CMM) in China. In the 1930's, a number of scientific research institutions were established in China, such as, the Institute of Physiology, National Academy of Peiping and the pharmaceutical laboratory of the experimental hygiene station, National Economic Council. Experts undertook extensive research on CMM. They injected the rough extractum or purified active constituent in laboratory animals to observe the characteristics of drugs and published a series of treatises. They made experimental objectives and selected experimental herbs according to TCM theory. Their inheritance and innovation in the research demonstrated better rationality than simultaneous overseas scholars to whom they were therefore superior. PMID:22782026

Zhao, Ji-Meng

2012-03-01

397

Spectral modulation observed in Chl-a by ultrafast laser spectroscopy.  

PubMed

Broadband real-time dynamic vibronic coupling in Chl-a were experimentally studied using few cycle laser pulses of 6.8fs duration and a 128-channnel lock-in amplifier. Thanks to the extreme temporal resolution benefitting from the ultrashort laser pulse, the real-time modulation of the electronic transition energy induced by the molecular vibrations were calculated by the time dependent first moments of the bleaching band. The transition energy was found to be modulated periodically with the same frequencies of molecular vibration found in the Fourier amplitude spectrum of the difference absorbance real-time traces. This was interpreted to be due to the difference in the effective transition energy associated with the wavepacket motion induced by the equilibrium positions of potential curves between the ground state and the excited state. Using the values, Huang-Rhys factors for several vibrational modes involved in the spectral modulation at the room-temperature have been determined. PMID:22109125

Du, Juan; Nakata, Kazuaki; Jiang, Yongliang; Tokunaga, Eiji; Kobayashi, Takayoshi

2011-11-01

398

Effects of various drug therapies on Kleine-Levin syndrome: a case report.  

PubMed

Kleine-Levin syndrome (KLS) is a rare sleep disorder, predominantly affecting adolescent males, which presents as recurrent episodes of hypersomnia, behavioral and cognitive disturbances, hyperphagia and sometimes hypersexuality (Lisk, "Kleine-Levin syndrome." Pract Neurol 2009;9:42-45). Modafinil has been reported to show an effect in shortening the duration of symptomatic periods, but does not affect the recurrence rate (Huang et al., "Kleine-Levin syndrome: current status." Med Clin N Am 2010;94:557-562). However, no single drug therapy has been consistently successful, despite various psychotropic agents, including lithium, anticonvulsants and antidepressants, having been systematically tried (Arnulf et al., "Kleine-Levin syndrome: a systematic study of 108 patients." Ann Neurol 2008;63:482-492). This study reports a male adolescent with KLS who received several courses of drug therapy, providing a chance to compare differential drug effects over time. PMID:22520717

Yao, Chi-Chun; Lin, Ying; Liu, Hui-Ching; Lee, Chau-Shoun

2012-04-18

399

Vertebral body recollapse without trauma after kyphoplasty with calcium phosphate cement.  

PubMed

Traditionally, immobilization and external bracing has been recommended for patients with type A traumatic and non-osteoporotic fractures that do not present neurological deficits or significant instability. Nevertheless, several authors have recently suggested the possibility to treat thoraco-lumbar and lumbar vertebral compression post-traumatic fractures using standalone balloon kyphoplasty with osteoconductive filler materials, such as calcium phosphate (CPC). Maestretti and Huang have demonstrated the advantages of this technique showing an almost immediate return to daily activities without the inconvenience of wearing a brace, pain reduction, minimal operative risks and maintenance of stability, therefore proposing this as a first-choice technique in young patient needing rapid spine stability. The authors present a case of vertebral body recollapse after kyphoplasty with calcium phosphate cement (CPC) in a 47-year-old man with an A1.2 post-traumatic L1 compression fracture. PMID:21468725

Piazzolla, Andrea; De Giorgi, Giuseppe; Solarino, Giuseppe

2011-04-06

400

An approximate way to subtract the mechanical spectra of deposited materials from a composite reed-vibration method  

NASA Astrophysics Data System (ADS)

A new experimental method has been designed to measure the mechanical spectra (complex Young's modulus Y*=Y?+iY?? versus temperature) of materials from liquid to solid state [X.N. Ying, Y.H. Yuan, L. Zhang, Y.N. Huang, Y.N. Wang, X.L. Wang, D.S. Zhou, G. Xue, Rev. Sci. Instr. 77 (2006) 053902]. The mechanical spectrum of material can be obtained by the subtraction from a composite system consisting a substrate reed and materials deposited on the substrate. In this report, an approximate way is shown to subtract the mechanical spectra of the deposited material from the composite system. And normalized mechanical spectra of glycerol and 1,2-propanediol carbonate were reproduced and they fit the data in Ying et al. very well. Furthermore, the approximate way might be more applicable since no regular shape of deposited materials is required.

Ying, X. N.

2007-01-01

401

Vibrational equilibration in absorption difference spectra of chlorophyll a.  

PubMed

We describe Franck-Condon simulations of vibrational cooling effects on absorption difference spectra in chlorophyll a (Chl a). The relative contributions of vibrational equilibration in the electronic ground and excited states depend on the pump and probe wavelengths. For Franck-Condon-active vibrational modes exhibiting small Huang-Rhys factors (S < 0.1, characteristic in Chl a pigments), vibrational thermalization causes essentially no spectral changes when the origin band is excited. Significant spectral evolution does occur for S < 0.1 when the 0-1 and 1.0 (hot) vibronic bands are excited. However, vibrational equilibration in these cases causes no spectral shifting in the empirical photobleaching/stimulated emission band maximum. This result bears on the interpretation of time-resolved absorption difference spectra of Chl a-containing antennae such as the Chl a/b light-harvesting peripheral antenna of photosystem II. PMID:8599680

Struve, W S

1995-12-01

402

Features of electrostatic landscape on graphene surfaces  

NASA Astrophysics Data System (ADS)

Electronic inhomogeneities in graphenes on the substrate are important for understanding the limiting factors for future device applications. One can study the length scale and distribution of potentials on single or few layers graphene sheets with local probe methods. We employ scanning probe imaging techniques such as AFM and EFM in ambient conditions and scanning electron microscopy for correlating studies of topological and electrostatic variations in a variety of mechanically cleaved graphenes and chemically modified graphene sheets. Enhanced contrast in phase signal, that is tunable via tip-substrate bias, indicates variations in the potential distribution which differ form the topographic landscapes. The nature of these structures has yet to be explored. Authors would like to thank for graphene oxide samples provided by L. Cote, J. Huang (MSE, Northwestern University).

Kuljanishvili, Irma; Dikin, Dmitriy

2010-03-01

403

Origin of Long-Lived Coherences in Light-Harvesting Complexes  

PubMed Central

A vibronic exciton model is applied to explain the long-lived oscillatory features in the two-dimensional (2D) electronic spectra of the Fenna–Matthews–Olson (FMO) complex. Using experimentally determined parameters and uncorrelated site energy fluctuations, the model predicts oscillations with dephasing times of 1.3 ps at 77 K, which is in a good agreement with the experimental results. These long-lived oscillations originate from the coherent superposition of vibronic exciton states with dominant contributions from vibrational excitations on the same pigment. The oscillations obtain a large amplitude due to excitonic intensity borrowing, which gives transitions with strong vibronic character a significant intensity despite the small Huang–Rhys factor. Purely electronic coherences are found to decay on a 200 fs time scale.

2012-01-01

404

3D Modeling of Laser Propagation in Ionizing Gas and Plasma  

NASA Astrophysics Data System (ADS)

The interaction of a high intensity laser with ionizing gas and plasmas is of current interest for both Laser Wakefield Accelerators and x-ray generation. We have developed a 3D fluid simulation code based on the same quasistatic approximation used in the 2D code WAKE [1]. The object oriented structure of the code also allows it to couple to the quickPIC particle code [2]. We will present 3D studies of the ionization scattering instability [3], which occurs when a laser pulse propagates in an ionizing gas. [1] P. Mora and T. Antonsen, Jr., Phys. Plasmas 4(1), January 1997 [2] J. Cooley, T. Antonsen, Jr., C. Huang, etal., Proceedings, Advanced Accelerator Concepts, 2002 [3] Z. Bian and T. Antonsen, Jr., Phys. Plasmas 8(7), July 2001 * work supported by NSF and DOE

Cooley, J.; Antonsen, T., Jr.; Huang, C.; Mori, W.

2003-10-01

405

Transforming growth factor beta (TGF-beta) type V receptor has a TGF-beta-stimulated serine/threonine-specific autophosphorylation activity.  

PubMed

The transforming growth factor beta (TGF-beta) type V receptor, a newly identified high molecular weight TGF-beta receptor (M(r) approximately 400,000) has been purified from bovine liver plasma membranes (O'Grady, P., Kuo, M.-D., Baldassare, J. J., Huang, S. S., and Huang, J. S. (1991) J. Biol. Chem. 266, 8583-8589). The purified TGF-beta type V receptor underwent autophosphorylation at serine residues when incubated with [gamma-32P]ATP in the presence of 0.1% beta-mercaptoethanol and 2.5 mM MnCl2. This phosphorylation was stimulated by preincubation with TGF-beta. The preferred exogenous substrate for the Ser/Thr-specific phosphorylation activity of the type V receptor was found to be bovine casein. The TGF-beta type V receptor could be affinity-labeled with 5'-p-[adenine-8-14C]fluorosulfonylbenzoyl adenosine. Polylysine appeared to stimulate the autophosphorylation of the TGF-beta type receptor in the presence of [gamma-32P]ATP and the incorporation of 5'-p-[adenine-8-14C]fluorosulfonylbenzoyl adenosine into the TGF-beta type V receptor. The amino acid sequence analysis of the peptide fragments produced by cyanogen bromide cleavage of the purified TGF-beta type V receptor revealed that a peptide, namely CNBr-19, contained an amino acid sequence which shows homology to the putative ATP binding site of the receptors for activin, the Caenorhabditis elegans daf-1 gene product, and TGF-beta type II receptor (Lin, H. Y., Wang, Y.-F., Ng-Eaton, E., Weinberg, R. A., and Lodish, H. F. (1992) Cell 68, 775-785). These results suggest that the TGF-beta type V receptor is a Ser/Thr-specific protein kinase and belongs to the new class of membrane receptors associated with a Ser/Thr-specific protein kinase activity. PMID:1328218

O'Grady, P; Liu, Q; Huang, S S; Huang, J S

1992-10-15

406

Mutational analysis of the conserved motifs of influenza A virus polymerase basic protein 1.  

PubMed Central

Influenza virus polymerase complex is a heterotrimer consisting of polymerase basic protein 1 (PB1), polymerase basic protein 2 (PB2), and polymerase acidic protein (PA). Of these, only PB1, which has been implicated in RNA chain elongation, possesses the four conserved motifs (motifs I, II, III, and IV) and the four invariant amino acids (one in each motif) found among all viral RNA-dependent RNA or RNA-dependent DNA polymerases. We have modified an assay system developed by Huang et al. (T.-J. Huang, P. Palese, and M. Krystal, J. Virol. 64:5669-5673, 1990) to reconstitute the functional polymerase activity in vivo. Using this assay, we have examined the requirement of each of these motifs of PB1 in polymerase activity. We find that each of these invariant amino acids is critical for PB1 activity and that mutation in any one of these residues renders the protein nonfunctional. We also find that in motif III, which contains the SSDD sequence, the signature sequence of influenza virus RNA polymerase, SDD is essentially invariant and cannot accommodate sequences found in other RNA viral polymerases. However, conserved changes in the flanking sequences of SDD can be partially tolerated. These results provide the experimental evidence that influenza virus PB1 possesses a similar polymerase module as has been proposed for other RNA viruses and that the core SDD sequence of influenza virus PB1 represents a sequence variant of the GDN in negative-stranded nonsegmented RNA viruses, GDD in positive-stranded RNA virus and double-stranded RNA viruses, or MDD in retroviruses. Images

Biswas, S K; Nayak, D P

1994-01-01

407

M{sub i} (i = 1-5) subshell fluorescence and Coster-Kronig yields for elements with 67 {<=} Z {<=} 92  

SciTech Connect

A complete set of the M{sub i} (i = 1-5) subshell fluorescence and Coster-Kronig (CK) yields has been generated by interpolation for elements with 67 {<=} Z {<=} 92 from the Dirac-Hartree-Slater (DHS) model based values tabulated for a limited number of elements, considering the cutoff/onset of different CK transitions in accordance with the CK transition energies evaluated in the present work. The CK transition energies have been deduced from tabulated values of the Dirac-Hartree-Fock-Slater model based neutral atom binding energies [K. Huang, M. Aoyagi, M.H. Chen, B. Crasemann, H. Mark, At. Data Nucl. Data Tables 18 (1976) 243] and the L{sub i} (i = 1-3) subshell CK transition energies [M.H. Chen, B. Crasemann, K. Huang, M. Aoyagi, H. Mark, At. Data Nucl. Data Tables 19 (1977) 97] in order to establish the cutoff/onset of different CK transitions at specific atomic numbers. A second set of the M{sub i} (i = 1-5) subshell fluorescence yields have also been deduced using radiative widths computed from the Dirac-Fock (DF) model based X-ray emission rates, and the total widths reevaluated to incorporate the DF model based radiative widths in place of those based on the DHS model. Further, the CK-corrected ({nu}{sub i}) and average fluorescence ({omega}{sub M}) fields, which are experimentally important, have been evaluated from the generated set of CK yields and two sets of fluorescence yields.

Chauhan, Yogeshwar [University College of Engineering, Punjabi University, Patiala 147002 (India); Puri, Sanjiv [University College of Engineering, Punjabi University, Patiala 147002 (India)], E-mail: sanjivpurichd@yahoo.com

2008-01-15

408

Quantum IR line list of NH3 and isotopologues for ISM and dwarf studies  

NASA Astrophysics Data System (ADS)

Ammonia (NH3) was the first polyatomic molecule observed in the ISM. Its importance in interstellar molecules is only second to CO because its rovibrational spectroscopic signature can be used very effectively at deducing the conditions of the interstellar environment such as temperature and density, and because it is found in so many different interstellar objects in a wide temperature range. However, experimental determination of NH3 IR spectra is extremely difficult due to the large-amplutide inversion vibration, and the existing HITRAN2008 database for NH3 is limited in temperature, coverage, completeness, and accuracy. With rapid progress in theoretical chemistry and computational resources, now we are able to generate a highly reliable/accurate IR line list of NH3 (and its isotopologues) for astronomical studies. Exact quantum rovibrational computations on an empirically refined potential energy surface (with nonadiabatic corrections included) have achieved accuracies of 0.02-0.05 cm-1 (for line position) and better than 85-95% (for line intensity) for both NH3 and 15NH3 spectra. The unique feature of our work is that our predictions are essentially as accurate as reproducing existing measurements, suitable for synthetic simulation of various astrophysical environments or objects. The reliabilty and accuracy of our predictions for missing bands and higher energies computed on HSL-2 (Fig. 1) have been proved by the most recent high-resolution experiments and extended up to 7000 cm-1. See Huang et al. 2008, Huang et al. 2011, & Sung et al. 2012 for more details.

Huang, Xinchuan; Schwenke, David W.; Lee, Timothy J.; Sung, Keeyoon; Brown, Linda R.

2013-03-01

409

CO-ANALYSIS OF SOLAR MICROWAVE AND HARD X-RAY SPECTRAL EVOLUTIONS. I. IN TWO FREQUENCY OR ENERGY RANGES  

SciTech Connect

Solar microwave and hard X-ray spectral evolutions are co-analyzed in the 2000 June 10 and 2002 April 10 flares, and are simultaneously observed by the Owens-Valley Solar Array in the microwave band and by Yohkoh/Hard X-ray Telescope or RHESSI in the hard X-ray band, with multiple subpeaks in their light curves. The microwave and hard X-ray spectra are fitted by a power law in two frequency ranges of the optical thin part and two photon energy ranges, respectively. Similar to an earlier event in Shao and Huang, the well-known soft-hard-soft pattern of the lower energy range changed to the hard-soft-hard (HSH) pattern of the higher energy range during the spectral evolution of each subpeak in both hard X-ray flares. This energy dependence is actually supported by a positive correlation between the overall light curves and spectral evolution in the lower energy range, while it becomes an anti-correlation in the higher energy range. Regarding microwave data, the HSH pattern appears in the spectral evolution of each subpeak in the lower frequency range, which is somewhat similar to Huang and Nakajima. However, it returns back to the well-known pattern of soft-hard-harder for the overall spectral evolution in the higher frequency range of both events. This frequency dependence is confirmed by an anti-correlation between the overall light curves and spectral evolution in the lower frequency range, but it becomes a positive correlation in the higher frequency range. The possible mechanisms are discussed, respectively, for reasons why hard X-ray and microwave spectral evolutions have different patterns in different energy and frequency intervals.

Song Qiwu; Huang Guangli [Purple Mountain Observatory, Nanjing 210008 (China); Nakajima, Hiroshi, E-mail: songqw@pmo.ac.cng, E-mail: lhuang@pmo.ac.cn, E-mail: nakaji15@dia.janis.or.jp [Nobeyama Solar Radio Observatory, Nobeyama, Minamisaku, Nagano 384-1305 (Japan)

2011-06-20

410

Continental Heat Gain in the Global Climate System  

NASA Astrophysics Data System (ADS)

Observed increases in 20th century surface-air temperatures are one consequence of a net energy flux into all major components of the Earth climate system including the atmosphere, ocean, cryosphere, and lithosphere. Levitus et al. [2001] have estimated the heat gained by the atmosphere, ocean and cryosphere as 18.2x1022 J, 6.6x1021 J, and 8.1x1021 J, respectively, over the past half-century. However the heat gain of the lithosphere via a heat flux across the solid surface of the continents (30% of the Earth's surface) was not addressed in the Levitus analysis. Here we calculate that final component of Earth's changing energy budget, using ground-surface temperature reconstructions for the continents [Huang et al., 2000]. These reconstructions have shown a warming of at least 0.5 K in the 20th century and were used to determine the flux estimates presented here. In the last half-century, the interval of time considered by Levitus et al., there was an average flux of 40 mW/m2 across the land surface into the subsurface, leading to 9.2x1021 J absorbed by the ground. This amount of heat is significantly less than the energy transferred into the oceans, but of the same magnitude as the energy absorbed by the atmosphere or cryosphere. The heat inputs into all the major components of the climate system - atmosphere, ocean, cryosphere, lithosphere - conservatively sum to more than 20x1022 J during the last half-century, and reinforce the conclusion that the warming in this interval has been truly global. Huang, S., Pollack, H.N., and Shen, P.-Y. 2000. Temperature trends over the past five centuries reconstructed from borehole temperatures. Nature. 403. 756-758 Levitus, S., Antonov, J., Wang, J., Delworth, T. L., Dixon, K. and Broccoli, A. 2001. Anthropogenic warming of the Earth's climate system. Science, 292, 267-270

Smerdon, J. E.; Beltrami, H.; Pollack, H. N.; Huang, S.

2001-12-01

411

Nocturnal Stratification of the Ionospheric F-layer over Karachi, Pakistan during Solar Cycle 22 (1986-96)  

NASA Astrophysics Data System (ADS)

This study has been carried out employing the ionospheric data of Karachi (24.95o N, 67.14o E) for a complete Solar Cycle-22 (1986-96), acquired by means of Digisonde DGS-256. The visual observations of data as shown that some times Nocturnal Ionospheric Stratification at Karachi do occur. However, Nocturnal Ionospheric Stratification is very rare in middle and lower latitudes (TAN and HUANG, 1985). Therefore, the present study is undertaken. Only the night-time F-layer Stratification cases have been included in this study. It is revealed that the Nocturnal Stratification in F-layer at Karachi is mainly a post-midnight phenomenon, under both magnetically quite and disturbed conditions. Though it may occur on pre and post -midnight periods, its occurrence in all the seasons is frequent (95%) in post mid-night period 0215-0500 LT . Only 5% cases were observed in pre mid-night period 2200-0000 LT. Its occurrence during Solar Maximum (1989-90) is significantly greater than at the two solar minimum i.e. 1986-87 and 1995-96. However, its maximum occurrence is observed in 1992 i.e. 2 years after the solar maximum. The seasons in order of its maximum occurrence are Winter, Equinoxes and Summer. Even in Winter its occurrence is observed to be the highest in the month of January. Nocturnal Ionospheric Stratification at Karachi may and may not occur on a TID (Traveling Ionospheric Disturbances) night, irrespective of the fact whether the night is magnetically quite and disturbed. This shows that the nocturnal Stratification is not caused by a TID as reported by TA N and HUANG (1985) over Wuchang (30.5o N, 11.4o E), China. Moreover, Karachi does not lie under any of the zones of particle precipitation described by BOSS and SMITH (1980). Therefore, a future study on the cause of Nocturnal Ionospheric Stratification is clearly required.

Zafar, H.; Zaidi, S.

412

TreeMAC: Localized TDMA MAC protocol for real-time high-data-rate sensor networks  

USGS Publications Warehouse

Earlier sensor network MAC protocols focus on energy conservation in low-duty cycle applications, while some recent applications involve real-time high-data-rate signals. This motivates us to design an innovative localized TDMA MAC protocol to achieve high throughput and low congestion in data collection sensor networks, besides energy conservation. TreeMAC divides a time cycle into frames and each frame into slots. A parent node determines the children's frame assignment based on their relative bandwidth demand, and each node calculates its own slot assignment based on its hop-count to the sink. This innovative 2-dimensional frame-slot assignment algorithm has the following nice theory properties. First, given any node, at any time slot, there is at most one active sender in its neighborhood (including itself). Second, the packet scheduling with TreeMAC is bufferless, which therefore minimizes the probability of network congestion. Third, the data throughput to the gateway is at least 1/3 of the optimum assuming reliable links. Our experiments on a 24-node testbed show that TreeMAC protocol significantly improves network throughput, fairness, and energy efficiency compared to TinyOS's default CSMA MAC protocol and a recent TDMA MAC protocol Funneling-MAC. Partial results of this paper were published in Song, Huang, Shirazi and Lahusen [W.-Z. Song, R. Huang, B. Shirazi, and R. Lahusen, TreeMAC: Localized TDMA MAC protocol for high-throughput and fairness in sensor networks, in: The 7th Annual IEEE International Conference on Pervasive Computing and Communications, PerCom, March 2009]. Our new contributions include analyses of the performance of TreeMAC from various aspects. We also present more implementation detail and evaluate TreeMAC from other aspects. ?? 2009 Elsevier B.V.

Song, W. -Z.; Huang, R.; Shirazi, B.; LaHusen, R.

2009-01-01

413

Theoretical NH{_3} Spectra in 5800-7000 CM-1 Region and CO{_2} IR Intensity: Updates  

NASA Astrophysics Data System (ADS)

Recently we have successfully applied the "Best Theory + High-resolution Experimental Data" strategy to NH{_3} and CO{_2}. The essential strategy is to refine a high quality, purely ab initio potential energy surface (PES) with reliable high resolution experimental data, so the IR line lists computed on the refined PES and dipole moment surface (DMS) can go beyond simple data reproduction. The goal is to make reliable predictions for higher J/K/energy rovibrational transitions with similar accuracies, i.e. 0.01-0.03 cm-1. The reliability and accuracy of data included in the refinement largely determines the quality of predictions and the ultimate merit of our work. With recent 14NH{_3} experiments in 5800 - 7000 cm-1, the effective coverage (with 0.01-0.03 cm-1 accuracy) of our NH{_3} PES has extended to this complex spectral region. Excellent agreement between current experiment analysis and our primitive HSL-3 PES refinement will be presented, and source of discrepancies will be discussed. The synergy between the experiments and theory is of great value. For CO{_2}, we have updated the theoretical IR intensity of the 12C16O{_2} line list with a more reliable DMS, then carried out very detailed comparisons with both pure experimental data and HITRAN/CDSD models. Results suggest that our line lists should be useful for the astronomical or earth-based detection of CO{_2} isotopologues. X. Huang, D.W. Schwenke, and T.J. Lee, J. Chem. Phys. 129, 214304 (2008); J. Chem. Phys. 134, 044320/044321 (2011). X. Huang, D.W. Schwenke, S.A. Tashkun, and T.J. Lee J. Chem. Phys. 136, submitted (2012).

Huang, Xinchuan; Schwenke, David W.; Lee, Timothy J.; Sung, Keeyoon; Brown, Linda R.; Tashkun, Sergey A.

2012-06-01

414

Attenuation of protein kinase C and cAMP-dependent protein kinase signal transduction in the neurogranin knockout mouse.  

PubMed

Neurogranin (Ng) is a brain-specific, postsynaptically located protein kinase C (PKC) substrate, highly expressed in the cortex, hippocampus, striatum, and amygdala. This protein is a Ca(2+)-sensitive calmodulin (CaM)-binding protein whose CaM-binding affinity is modulated by phosphorylation and oxidation. To investigate the role of Ng in neural function, a strain of Ng knockout mouse (KO) was generated. Previously we reported (Pak, J. H., Huang, F. L., Li, J., Balschun, D., Reymann, K. G., Chiang, C., Westphal, H., and Huang, K.-P. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 11232-11237) that these KO mice displayed no obvious neuroanatomical abnormality, but exhibited deficits in learning and memory and activation of Ca(2+)/CaM-dependent protein kinase II. In this report, we analyzed several downstream phosphorylation targets in phorbol 12-myristate 13-acetate- and forskolin-treated hippocampal slices from wild type (WT) and KO mice. Phorbol 12-myristate 13-acetate caused phosphorylation of Ng in WT mice and promoted the translocation of PKC from the cytosolic to the particulate fractions of both the WT and KO mice, albeit to a lesser extent in the latter. Phosphorylation of downstream targets, including mitogen-activated protein kinases, 90-kDa ribosomal S6 kinase, and the cAMP response element binding protein (CREB) was significantly attenuated in KO mice. Stimulation of hippocampal slices with forskolin also caused greater stimulation of protein kinase A (PKA) in the WT as compared with those of the KO mice. Again, phosphorylation of the downstream targets of PKA was attenuated in the KO mice. These results suggest that Ng plays a pivotal role in regulating both PKC- and PKA-mediated signaling pathways, and that the deficits in learning and memory of spatial tasks detected in the KO mice may be the result of defects in the signaling pathways leading to the phosphorylation of CREB. PMID:11912190

Wu, Junfang; Li, Junfa; Huang, Kuo-Ping; Huang, Freesia L

2002-03-22

415

Excitation wavelength-dependent electron-phonon and electron-vibrational coupling in the CP29 antenna complex of green plants.  

PubMed

Electron-phonon and electron-vibrational coupling strengths of a weakly (excitonically) coupled chlorophyll a S1-->S0 transition of the CP29 antenna complex of plant photosystem II were studied by difference fluorescence-line-narrowing spectroscopy at 4.5 K. A strong, almost linear increase of the electron-phonon coupling strength toward longer wavelengths was observed, with Huang-Rhys factors Sph increasing from 0.41+/-0.05 at 680 nm to about 0.66+/-0.07 at 688 nm. The former and latter wavelengths are located close to the peak and on the red edge of the inhomogeneous site distribution function, respectively. The experimentally obtained wavelength dependence of Sph may originate either from an alteration of the electron-phonon coupling strength by the local environment of the fluorescing chromophore and/or from the presence of two isoforms of CP29, which are characterized by different coupling strengths to the protein environment. The one-phonon profile peaks at omegam=22 cm(-1) and is described by an asymmetric function composed of a Gaussian low-energy wing and a Lorentzian high-energy tail with half-widths at half-maximum of 10+/-1 and 60+/-10 cm(-1), respectively. Thirty-nine individual vibrational modes between 90 and 1665 cm(-1) were resolved, and their Huang-Rhys factors were determined, which fall in the range between 0.0004 and 0.032. The broad feature present in the overlap region of phonon and vibrational modes at about 90 cm(-1) is characterized by S=0.048. An integral value of vibrational coupling strengths Svib=0.36+/-0.05 was determined, which is similar to that observed earlier for the trimeric LHC II complex. PMID:18067279

Rätsep, Margus; Pieper, Jörg; Irrgang, Klaus-Dieter; Freiberg, Arvi

2007-12-08

416

Reconstruction of phase-shifted fiber Bragg grating parameters using genetic algorithm over thermally-modulated reflection intensity spectra  

NASA Astrophysics Data System (ADS)

This paper presents a numerical method for the inverse extraction of the multiple physical parameters of phase-shifted fiber Bragg gratings (FBGs). In the proposed approach, the reflection intensity spectra produced by two known temperature distributions are taken as objective functions and a genetic algorithm is then employed to perform an iterative search for the corresponding parameters of the phase-shifted FBG, including the grating period, the grating position, the grating length, the refractive-index modulation depth, the apodize factor, and the phase-shift position. The numerical results confirm that the proposed method successfully synthesizes the parameters of phase-shifted FBGs with various structures with a high degree of accuracy. Furthermore, the method has the advantages of simplicity, low cost and a nondestructive nature. Accordingly, the method is suitable for widespread application in the fiber communications and fiber laser components fields.KeywordsPhase-shifted fiber Bragg grating (FBG)Genetic algorithm (GA)Parameter synthesisTemperature distributionReferencesR.KashyapFiber Bragg Gratings1999Academic PressSan DiegoN.Q.NgoS.Y.LiL.N.BinhS.C.TjinA phase-shifted linearly chirped fiber Bragg grating with tunable bandwidthOpt. Commun.2602006438441W.H.LohR.I.Laming1.55 ?m phase-shifted distributed feedback fibre laserElectron. Lett.31199514401442C.MarraA.NirmalathasD.NovakC.LimL.ReekieJ.A.BesleyC.WeeksN.BakerWavelength-interleaved OADMs incorporating optimized multiple phase-shifted FBGs for fiber-radio systemsJ. Lightwave Technol.21120033239A.A.AbramovB.J.EggletonJ.A.RogersR.P.EspindolaA.HaleR.S.WindelerT.A.StrasserElectrically tunable efficient broad-band fiber filterIEEE Photon. Technol. Lett.111999445447H.LeeG.AgrawalBandwidth equalization of purely phase-sampled fiber Bragg gratings for broadband dispersion and dispersion slope compensationOpt. Express1223200455955602D.W.HuangC.C.YangReconstruction of fiber grating refractive-index profiles from complex Bragg reflection spectraAppl. Opt.38199944944499C.J.S.de MatosP.TorresL.C.G.ValenteW.MargulisR.StubbeFBG characterization and shaping by local pressureJ. Lightwave Technol.198200112061211N.RousselS.MagneC.MartinezP.FerdinandMeasurement of index modulation along fiber Bragg gratings by side scattering and local heating techniquesOpt. Fiber Technol.51999119132H.C.ChengY.L.LoThe synthesis of multiple parameters of arbitrary FBGs via a genetic algorithm and two thermally modulated intensity spectraJ. Lightwave Technol.23200521582168J.F.HuangY.L.LoH.C.ChengS.H.HuangReconstruction of chirped fiber Bragg grating parameters and phase spectrum using two thermally modulated intensity spectra and genetic algorithmIEEE Photon. Technol. Lett.1822006346348T.ErdoganFiber grating spectraJ. Lightwave Technol.158199712771294S.Y.HuangM.LeBlancM.M.OhnR.M.MeasuresBragg intragrating structural sensingAppl. Opt.34199550035009Z.MichalewiczGenetic Algorithms + Data Structures = Evolution Programs1992Springer-VerlagNew YorkHsu-Chih Cheng was born in Yunlin, Taiwan, in September 1975. He received his B.S. degree from the Electronics Department of National Taiwan University of Science and Technology in 2000. His M.S. and Ph.D. degrees in electrical engineering from the National Cheng Kung University, Tainan, Taiwan, in 2002 and 2006, respectively. He has been a member of the faculty of the Computer and Communication Department, Diwan University, since 2007, where he is now an Assistant Professor. His major interests are in DWDM networking devices, fiber Bragg grating filters, genetic algorithms, fiber Bragg grating sensors, and multi-user communication systems.Jen-Fa Huang received his M.A.Sc. and Ph.D. degrees from the Department of Electrical Engineering at the University of Ottawa, ON, Canada, in 1981 and 1985, respectively. Since 1991, he has been a member of the Department of Electrical Engineering, National Cheng Kung University, Taiwan, where he is currently an Adjunct Professor in the Institute of Computer and Communication Engineering and the Institute of Opto-Electronic

Cheng, Hsu-Chih; Huang, Jen-Fa; Chen, Yen-Hsien

2008-01-01

417

Mid-Holocene variability of the East Asian monsoon based on bulk organic ?13C and C/N records from the Pearl River estuary, southern China  

NASA Astrophysics Data System (ADS)

Understanding the mid-Holocene dynamics of the East Asian monsoon (EAM) is integral to modelling the Holocene development of the global climate system (Webster et al., 1998). Thus the mid-Holocene EAM history was reconstructed using bulk organic carbon isotopes (?13C), total carbon to total nitrogen (C/N) ratios and total organic carbon (TOC) from a sediment core (UV1), at a mean resolution of 10 years, from the Pearl River estuary, southern China. Sedimentary ?13C, C/N and TOC from the Pearl River estuary is a good indicator of changes in monsoonal precipitation strength (Zong et al., 2006; Yang et al., 2010), eg sediments buried during a period of high precipitation exhibit a high proportion of terrigenous sediments, and have low ?13C and high C/N, and vice versa (Yu et al., 2010). Results suggest a general decreasing trend in monsoonal precipitation from 6650-2215 cal yr BP due to the weakening insolation over northern hemisphere most likely related to the current precession circle (An, 2000). Superimposed on this trend are apparent dry-wet oscillations at centennial to millennial timescales most likely in response to solar activity. Mismatch between ?13C and results from the Dongge Cave in southern China at millennial-timescale oscillations (Wang et al., 2005), may indicate that the ?13C from the Pearl River estuary reveals changes in precipitation in a broader area than the ?18O from Dongge Cave does. Reference An Z (2000) The history and variability of the East Asian paleomonsoon climate. Quaternary Science Reviews 19: 171-187. Wang Y, Cheng H, Edwards RL, He Y, Kong X, An Z, Wu J, Kelly MJ, Dykoski CA and Li X (2005) The Holocene Asian Monsoon: Links to Solar Changes and North Atlantic Climate. Science 308: 854-857. Webster PJ, Magaña VO, Palmer TN, Shukla J and Tomas RA (1998) Monsoons: Processes, predictability, and the prospects for prediction. Journal of Geophysical Research 103(C7): 14451-14510. Yang S, Tang M, Yim WWS, Zong Y, Huang G, Switzer AD and Saito Y Burial of organic carbon in Holocene sediments of the Zhujiang (Pearl River) and Changjiang (Yangtze River) estuaries. Marine Chemistry In Press, Corrected Proof. Yu F, Zong Y, Lloyd JM, Huang G, Leng MJ, Kendrick C, Lamb AL and Yim WWS (2010) Bulk organic ?13C and C/N as indicators for sediment sources in the Pearl River delta and estuary, southern China. Estuarine, Coastal and Shelf Science 87(4): 618-630. Zong Y, Lloyd JM, Leng MJ, Yim WW-S and Huang G (2006) Reconstruction of Holocene monsoon history from the Pearl River Estuary, southern China, using diatoms and carbon isotope ratios. The Holocene 16(2): 251-263.

Yu, F.; Lloyd, J. M.; Zong, Y.; Leng, M. J.; Switzer, A. D.; Yim, W. W.; Huang, G.

2010-12-01

418

Thermal Mechanical Evolution of the Eastern Tibetan Plateau  

NASA Astrophysics Data System (ADS)

The long term thermo-mechanical history of the Tibetan plateau is crucial to understand the present active deformation along its eastern margin as highlighted by the may 12 2008 Wenchuan Earthquake. Geophysical data indicate a 20 km Moho vertical offset underneath the Longmen Shan. This crustal thickening and the Tibetan plateau development result from tectonic accretion during the Mesozoic and Cenozoic.A key question is the relative impact of these events on the tectonic evolution of the eastern margin of the tibetan plateau. We propose a new structural map including published and new field observations and an augmented P-T-t study on the following structural units of the region : -Triassic turbidites are affected by intense upright folding and reverse faults associated with low-grade metamorphism reaching up to 450C .Turbidites are intruded by granitic plutons dated from 230 to 160 Ma. -Crystalline Proterozoic rocks exposed in the LongmenShan,(Penguan massif) and in the Gezong and Gongcai domes. Metasediments associated with the Gezong and Gongcai domes reach 500C around 260 Ma (Ar Ar on amphibole (Zhou et al 2008)). Cooling of these domes occurred between 159 and 50 Ma. The turbidites are thrusted over these rocks. -Amphibolite facies metasediments and metabasites, associated with migmatites and granites are exhumed in the Danba metamorphic dome and juxtaposed to the turbidites along a low-angle shear zone. Our data on metabasites show a peak metamorphism at 800C and 5kbar around 220 Ma. Two high grade metamorphic events are identified by Huang et al (2003a, 2003b) at 200 and 165 Ma (Indosinian). A 65 Ma U-Pb on monazite associated with sillimanite is obtain by Wallis et al (2003), but the signification of this age is understand. The metamorphic record of rocks of the Gezong dome and of the Danba area is different. These rocks probably represent different structural levels although the nature of the contact between them has not been identified. Perspectives for this work is to test, through the exhumation rate, the validity of the extreme views for the thickening and surrection of the eastern margin : the rigid one, where the thickening is the result of pile of crustal scale and the viscous one, where a ductile level flows and is stopped at the Yantze craton. Huang M. H., Buick I. S. and Hou L. W., 2003a. Tectonometamorphic evolution of the eastern Tibet plateau : evidence from the Central Songpan Garze Orogenic Belt, Western China. Journal of petrology, vol 44, 2, pp 255-278 Huang M., Maas R., Buick I. S. and Williams I. S., 2003b. Crustal response to continental collisions between the Tibet, South China and North China Blocks : geochronological constraints from the Songpan Garze Orogenic Belt, Western China. Journal of metamorphic geology, 21, pp 223-240 Wallis S. Tsujimori T., Aoya M., Kawakami T., Terada K., Suzuki K., Hyodo H. 2003. Cenozoic and Mesozoic metamorphism in the LongmenShan orogen : Implications for geodynamic models of eastern Tibet. Geology, vol 31, 9, pp 745-748. Zhou, M.-F., D.-P. Yan, et al. 2008. Structural and geochronological constraints on the tectono-thermal evolution of the Danba domal terrane, eastern margin of the Tibetan plateau. Journal of Asian Earth Sciences 33(5-6): 414-427.

Billerot, A.; de Sigoyer, J.; Duchene, S.; Vanderhaeghe, O.; Robert, A.

2008-12-01

419

OM/OC Ratio and Specific Attenuation Coefficient in Ambient Particulate Matter at a Rural Site in Southern Ontario: Implications for Aerosol Aging and Emission Sources  

NASA Astrophysics Data System (ADS)

Carbonaceous species (organic carbon (OC) and elemental carbon (EC)) contribute a large portion of atmospheric fine particle mass and influence air quality, human health, and climate forcing. However, their emission sources and atmospheric aging processes are not well understood. The OM/OC ratio, defined as the organic mass per unit OC mass, is useful to understand the degree of oxidation of aerosol particles in atmospheric processes. We define the modified BC/EC (mod BC/EC) ratio as the ratio of the non-scattering corrected absorption coefficient per unit mass of EC. The mod BC/EC ratio has a similar meaning as the site specific attenuation coefficient, which is an important parameter used to convert light absorption measurements to black carbon mass. The mod BC/EC ratio can vary due to light scattering effect on absorption measurements, in which the oxygenated organics may play a role. The pyrolysis organic carbon (POC) is defined as the carbon mass fraction obtained at T= 870°C under a pure helium environment using the thermal separation method [Huang et al., 2006]. Since POC mass is generally proportional to the amount of oxygenated OC, studying the relationships among OC, EC, POC, as well as OM/OC and mod BC/EC ratios may help us understand the mechanisms of aerosol aging from different emission sources. Two 1-month field studies were conducted at a rural site in southern Ontario (NW of Toronto) during fall 2005 and spring 2007. Quartz filter samples were collected and analyzed for OC, POC, and EC concentrations using a thermal/optical method [Huang et al., 2006]. Together with the total organic matter measured by an Aerodyne Aerosol Mass Spectrometer (AMS) and the absorption coefficient obtained from a Particle Soot Absorption Photometer (PSAP), the OM/OC and mod BC/EC ratios for ambient aerosols were obtained. Our results show that when air mass was mainly from south, OC, POC, and EC were relatively high, with average ratios of OC/EC, OM/OC, and POC/EC as 1.94, 1.41, and 0.52, respectively; this indicates significant anthropogenic impacts and relatively large portion of oxygenated OC, which might be due to either primary emissions or photo-chemical reactions occurred in a short period of time. When air mass was mainly from north, OC, POC, and EC were much lower, with average ratios of OC/EC, OM/OC, and POC/EC as 3.10, 1.20, and 0.79, respectively; this suggests less influence from anthropogenic emissions and relatively aged air mass from biogenic-source dominated clean air. Using POC, we estimate the specific attenuation at the site to be 5.8 m2 g-1 independent of the air mass origin. The relationships among OM/OC, mod BC/EC, and POC will be further discussed. References: Huang, L., Brook, J.R., Zhang, W., Li, S.M., Graham, L., Ernst, D., Chivulescu, A., and Lu, G. (2006) Stable isotope measurements of carbon fractions (OC/EC) in airborne particulate: a new dimension for source characterization and apportionment, Atmospheric Environment, 40, 2690-2705.

Chan, T. W.; Huang, L.; Leaitch, R.; Sharma, S.; Brook, J.; Slowik, J.; Abbatt, J.

2008-05-01

420

Kaolinite illitization at 300 C and 1000 bars with increasing time  

NASA Astrophysics Data System (ADS)

One of the important reactions producing illite as a consequence of burial diagenesis is the illitization of kaolinite, which has been investigated exstensively in both natural systems and experimental conditions. The rate of transformation of kaolinite into K-mica in alkaline solutions was reported by Velde.[1] Huang [2] studied the conversion of kaolinite into illite in KOH solution at several temperatures and he concluded that the conversion is two to three orders of magnitude faster than that of similar reactions at near-neutral conditions.[3] Most of a existing studies deal with the kinetics of kaolinite illitization using low solid/liquid ratios up to a maximum of 200 mg/mL.[4] They accept a dissolution-precipitation mechanism, which is clearly favoured by low solid/liquid ratios. Higher solid/liquid ratio, closer to the geological conditions expected in many kaolin-rich burial zones, would to favour a solid state-like reaction. The aim of the present study is to understand the influence of time on to the progress in the kaolinite illitization in KOH solution using a high solid-liquid ratio. Kaolinite has been converted into illitic clays in a 2.85 M KOH solution using a solid/liquid ratio of 1000 mg/mL, at 300 C,1000 bars and different reaction times. X-ray diffraction and IR spectroscopy have been used to follow the formation of new crystalline phases and the transformation of the Si and Al local environments and the octahedral sheet composition have been analysed by 29Si and 27Al MAS NMR spectroscopy. The results indicate that the first stage of kaolinite illitization is the crystallization of two different types of zeolites: zeolite F and natrolite (minor phase). The XRD patterns indicate that the kaolinite and zeolites progressively decrease is attained as reaction time increases giving rise to the crystallization of illite/muscovite. The formation of illite-muscovite is observed after only 1 hour of treatment by 27Al MAS NMR. Illite-muscovite and a small amount of kaolinite are the only phases present after 48 hours of treatment. References [1] Velde, B., Am. Mineral. 1965, 50, 436-449 [2] Huang, W.L. Clays and Clay Miner. 1993, 41, 645-654. [3] Chermak, J.A.; Rimstidt, J.D., Geochim. Cosmochim. Acta, 1990, 54, 2979-2990. [4] Bauer, A., Velde, B., Berger G. Appl. Geochem. 1998, 13, 619-629.

Mantovani, M.; Becerro, A. N.; Escudero, A.

2009-12-01

421

Determination of Ephedrine Alkaloids in Botanicals and Dietary Supplements by HPLC-UV  

PubMed Central

An international collaborative study was conducted of a high-performance liquid chromatography (HPLC)-UV method for the determination of the major (ephedrine [EP] and pseudoephedrine [PS]) and minor (norephedrine [NE], norpseudoephedrine [NP], methylephedrine [ME], and methylpseudoephedrine [MP]) alkaloids in selected dietary supplements representative of the commercially available products. Ten collaborating laboratories determined the ephedrine-type alkaloid content in 8 blind replicate samples. Five products contained ephedra ground herb or ephedra extract. These 5 products included ground botanical raw material of Ephedra sinica, a common powdered extract of Ephedra sinica, a finished product containing only Ephedra sinica ground botanical raw material, a complex multicomponent dietary supplement containing Ma Huang, and a high-protein chocolate flavored drink mix containing Ma Huang extract. In addition, collaborating laboratories received a negative control and negative control spiked with ephedrine alkaloids at high and low levels for recovery studies. Test extracts were treated to solid-phase extraction using a strong-cation exchange column to help remove interferences. The HPLC analyses were performed on a polar-embedded phenyl column using UV detection at 210 nm. Repeatability relative standard deviations (RSDr) ranged from 0.64–3.0% for EP and 2.0–6.6% for PS, excluding the high protein drink mix. Reproducibility relative standard deviations (RSDR) ranged from 2.1–6.6% for EP and 9.0–11.4% for PS, excluding the high protein drink mix. Recoveries ranged from 84.7–87.2% for EP and 84.6–98.2% for PS. The data developed for the minor alkaloids are more variable with generally unsatisfactory HORRATS(i.e., >2). However, since these alkaloids generally add little to the total alkaloid content of the products, the method gives satisfactory results in measuring total alkaloid content (RSDr 0.85–3.13%; RSDR 2.03–10.97%, HORRAT 0.69–3.23, exclusive of the results from the high protein drink). On the basis of these results, the method is recommended for Official First Action for determination of EP and PS in dietary supplements exclusive of the high protein drinks.

Roman, Mark C.; Gray, D.; Luo, G.; McClanahan, R.; Perez, R.; Roper, C.; Roscoe, V.; Shevchuk, C.; Suen, E.; Sullivan, D.; Walther, H.J.

2008-01-01

422

On-line structural integrity monitoring and defect diagnosis of steam generators using analysis of guided acoustic waves  

NASA Astrophysics Data System (ADS)

Integrity monitoring and flaw diagnostics of flat beams and tubular structures was investigated in this research using guided acoustic signals. The primary objective was to study the feasibility of using imbedded sensors for monitoring steam generator and heat exchanger tubing. A piezo-sensor suite was deployed to activate and collect Lamb wave signals that propagate along metallic specimens. The dispersion curves of Lamb waves along plate and tubular structures were generated through numerical analysis. Several advanced techniques were explored to extract representative features from acoustic time series. Among them, the Hilbert-Huang transform (HHT) is a recently developed technique for the analysis of non-linear and transient signals. A moving window method was introduced to generate the local peak characters from acoustic time series, and a zooming window technique was developed to localize the structural flaws. The dissertation presents the background of the analysis of acoustic signals acquired from piezo-electric transducers for structural defect monitoring. A comparison of the use of time-frequency techniques, including the Hilbert-Huang transform, is presented. It also presents the theoretical study of Lamb wave propagation in flat beams and tubular structures, and the need for mode separation in order to effectively perform defect diagnosis. The results of an extensive experimental study of detection, location, and isolation of structural defects in flat aluminum beams and brass tubes are presented. The time-frequency analysis and pattern recognition techniques were combined for classifying structural defects in brass tubes. Several types of flaws in brass tubes were tested, both in the air and in water. The techniques also proved to be effective under background/process noise. A detailed theoretical analysis of Lamb wave propagation was performed and simulations were carried out using the finite element software system ABAQUS. This analytical study confirmed the behavior of the acoustic signals acquired from the experimental studies. The results of this research showed the feasibility of on-line detection of small structural flaws by the use of transient and nonlinear acoustic signal analysis, and its implementation by the proper design of a piezo-electric transducer suite. The techniques developed in this research would be applicable to civil structures and aerospace structures.

Lu, Baofu

423

Spatial variations of temperature on a coastal site in Sweden as a response to insolation  

NASA Astrophysics Data System (ADS)

Temperature and humidity are major factors controlling ecosystem development. In a context of changing climate, the spatial distribution of temperature is likely to be affected, and species distribution might be subsequently modified. In particular, topographic heterogeneity is affecting the micro-climate and thus regulates the expansion or restriction of species in a landscape. During a change of climate, certain species might become restricted to localized refugia, or on the contrary expand from old refugia when the overall landscape becomes favorable. In this research we are using GIS based model of incoming solar radiation and subsequently derived monthly averaged temperatures to increase the understanding of changes in local climate and how it affects species repartition. The model is based on topography and observed variations in atmospheric conditions and is accounting for site latitude, elevation, surface orientation, daily and seasonal shifts in sun angle and the effect of shadows from the surrounding topography. A 2500 km2 forested field site located on the western coast of Sweden, along the Baltic Sea, is investigated both in terms of temperature heterogeneity and plant communities. We derive 50 m resolution insolation maps and analyze the response of monthly temperature to insolation. Surface and near surface temperatures are measured by a dense network of temperature sensors during the spring and summer of 2011 and are used for comparison with the modeled temperature maps. We investigate the potential of this modeling approach to scale climate trend analysis down to local climate change in heterogeneous landscapes. We build on the methodology used by Huang et al. (2008) in a mountain ecosystem and develop it for use on a coastal site that is largely influence by the presence of the sea. The time lag that is appropriate between insolation and subsequent temperature response appears to be influenced by the presence of a large water body and follows an exponential decay from the coastal to the inland measurement sites. We use the insolation and an appropriate time lag dependent on the distance to the sea in a linear regression model to derive estimates of spatially distributed temperature in our landscape. The dataset indicates a strong potential for monthly temperature to be predicted from solar radiation. Huang, S., Rich, P.M., Crabtree, R.L., Potter, C.S., Fu, P., 2008. Modeling Monthly Near-Surface Air Temperature from Solar Radiation and Lapse Rate: Application over Complex Terrain in Yellowstone National Park. Physical Geography 29, 158-178.

Vercauteren, N.; Dahlberg, J.; Lam, N.; Destouni, G.; Hylander, K.

2012-04-01

424

Comments on “Electrical conductivity of wadsleyite as a function of temperature and water content” by Manthilake et al.  

NASA Astrophysics Data System (ADS)

In a recent paper, Manthilake et al. [Manthilake, M.A.G.M., et al. Electrical conductivity of wadsleyite as a function of temperature and water content. Physics of the Earth and Planetary Interiors, in press] presented the results of experimental study on the electrical conductivity of wadsleyite and concluded that the influence of water is small at transition zone temperatures and that a high concentration of water (hydrogen) cannot explain the observed conductivity in the transition zone as oppose to the conclusion originally obtained by Huang et al. [Huang, X., Xu, Y., Karato, S., 2005. Water content of the mantle transition zone from the electrical conductivity of wadsleyite and ringwoodite. Nature 434, 746-749) from a similar experimental study. In this note, we discuss the causes of discrepancies between the results by two groups and show that almost all the differences are due to the experimental artifacts in the studies by Manthilake et al. and Yoshino et al. [Manthilake, M.A.G.M., et al. Electrical conductivity of wadsleyite as a function of temperature and water content. Physics of the Earth and Planetary Interiors, in press; Yoshino, T., Manthilake, G., Matsuzaki, T., Katsura, T., 2008a. Dry mantle transition zone inferred from the conductivity of wadsleyite and ringwoodite. Nature 451, 326-329] namely (i) the use of inappropriate method of determining electrical conductivity and (ii) the use of the data from a sample of wadsleyite with a substantial amount of water as a "dry" conductivity. A comparison of electrical conductivity of truly "dry" wadsleyite and olivine shows that the conductivity is similar at the same pressure and temperature. We also show that the use of one frequency method results in systematic errors in the conductivity measurements that explains the discrepancies in the results by two sets of studies. When an appropriate method for determining electrical conductivity (i.e., the impedance spectroscopy) is used and when the results of truly dry sample are used for the background dry conductivity, we find that the influence of water (hydrogen) is large enough to explain a majority of variation of electrical conductivity by the regional variation in water content.

Karato, Shun-ichiro; Dai, Lidong

2009-05-01

425

Brownian motion goes ballistic  

NASA Astrophysics Data System (ADS)

It is the randomness that is considered the hallmark of Brownian motion, but already in Einstein's seminal 1905 paper on Brownian motion it is implied that this randomness must break down at short time scales when the inertia of the particle kicks in. As a result, the particle's trajectories should lose its randomness and become smooth. The characteristic time scale for this transition is given by the ratio of the particle's mass to its viscous drag coefficient. For a 1 ?m glass particle in water and at room temperature, this timescale is on the order of 100 ns. Early calculations, however, neglected the inertia of the liquid surrounding the particle which induces a transition from random diffusive to non-diffusive Brownian motion already at much larger timescales. In this first non-diffusive regime, particles of the same size but with different densities still move at almost the same rate as a result of hydrodynamic correlations. To observe Brownian motion that is dominated by the inertia of the particle, i.e. ballistic motion, one has to observe the particle at significantly shorter time scales on the order of nanoseconds. Due to the lack of sufficiently fast and precise detectors, such experiments were so far not possible on individual particles. I will describe how we were able to observe the transition from hydrodynamically dominated Brownian motion to ballistic Brownian motion in a liquid. I will compare our data with current theories for Brownian motion on fast timescales that take into account the inertia of both the liquid and the particle. The newly gained ability to measure the fast Brownian motion of an individual particle paves the way for detailed studies of confined Brownian motion and Brownian motion in heterogeneous media. [4pt] [1] Einstein, A. "Uber die von der molekularkinetischen Theorie der W"arme geforderte Bewegung von in ruhenden Fl"ussigkeiten suspendierten Teilchen. Ann. Phys. 322, 549--560 (1905). [0pt] [2] Lukic, B., S. Jeney, C. Tischer, A. J. Kulik, L. Forro, and E.-L. Florin, 2005, Direct observation of nondiffusive motion of a Brownian particle, Physical Review Letters 95, 160601 (2005). [0pt] [3] Huang, R., Lukic, B., Jeney, S., and E.-L. Florin, Direct observation of ballistic Brownian motion on a single particle, arXiv:1003.1980v1 (2010). [0pt] [4] Huang, R., I. Chavez, K.M. Taute, B. Lukic, S. Jeney, M.G. Raizen, and E.-L. Florin, 2011, Direct observation of the full transition from ballistic to diffusive Brownian motion in a liquid, Nature Physics 7, 576--580 (2011).

Florin, Ernst-Ludwig

2012-02-01

426

Seismic imaging of the stagnant Pacific slab in the mantle transition zone under East Asia  

NASA Astrophysics Data System (ADS)

We used regional and global seismic tomography to determine high-resolution 3-D P-wave velocity structure of the crust and mantle down to 1200 km depth under Western Pacific to East Asia (Zhao, 2004, 2007; Huang and Zhao, 2006). A large number of arrival times of P, pP, PP and PcP waves recorded by many seismic stations in East Asia are used in the tomographic inversions. The subducting Pacific slab is imaged clearly as a high-velocity zone from the oceanic trenches down to 670-km depth, and intermediate-depth and deep earthquakes are located within the slab. The Pacific slab becomes stagnant in the mantle transition zone under eastern China. The western edge of the stagnant slab is generally parallel with the Japan trench and the Ryukyu trench and roughly coincides with a prominent surface topographic boundary in East China. Although there are some discrepancies between the topographic boundary and the western edge of the stagnant slab, both of them are located approximately 1800 km west of the trenches. The entire Pacific slab is stagnant in the mantle transition zone under Northeast China (53-37 degree north latitude). Under 37-28 degree north latitude, however, some of the slab materials are visible below the 670-km discontinuity, though most of the slab materials are still in the transition zone, suggesting that part of the slab materials have started to drop down to the lower mantle. Under the Mariana arc, the Pacific slab penetrates directly down to the lower mantle. It is also visible that the Philippine Sea slab has subducted down to the mantle transition zone depth under western Japan and the Ryukyu back-arc region (Abdelwahed and Zhao, 2007). There are three active intraplate volcanoes in China. The Changbai and Wudalianchi volcanoes in Northeast China are underlain by significant slow anomalies in the upper mantle, above the stagnant Pacific slab, suggesting that the two active volcanoes are not hot spots but a kind of back-arc volcanoes associated with the deep subduction of the Pacific slab and its stagnancy in the transition zone as well as corner flow in the big mantle wedge (BMW) above the stagnant slab. The active Tengchong volcano in Southwest China is related to the eastward subduction of the Burma microplate. References: D. Zhao (2004) Phys. Earth Planet. Inter. 146, 3-34. D. Zhao (2007) Gondwana Research 12, 335-355. J. Huang, D. Zhao (2006) J. Geophys. Res. 111, B09305.

Zhao, D.

2008-12-01

427

Intraplate volcanism and mantle dynamics in East Asia: Big mantle wedge (BMW) model (Invited)  

NASA Astrophysics Data System (ADS)

In the East Asia continent there are many Cenozoic volcanoes, but only a few are still active now, such as the Changbai, Wudalianchi, and Tengchong volcanoes which have erupted several times in the past 1000 years. Although many studies have been made by using various approaches, the origin of the intraplate volcanoes in East Asia is still not very clear. Recently we used regional and global seismic tomography to determine high-resolution 3-D mantle structure under Western Pacific to East Asia (Zhao, 2004; Huang and Zhao, 2006; Zhao et al., 2009). Our results show prominent low-velocity anomalies from the surface down to 410 km depth beneath the intraplate volcanoes and a broad high-velocity anomaly in the mantle transition zone under East Asia. Focal-mechanism solutions of deep earthquakes indicate that the subducting Pacific slab under the Japan Sea and the East Asia margin is subject to compressive stress regime. These results suggest that the Pacific slab meets strong resistance at the 660-km discontinuity and so it becomes stagnant in the mantle transition zone under East Asia. The Philippine Sea slab has also subducted down to the mantle transition zone under western Japan and the Ryukyu back-arc region. The western edge of the stagnant slab is generally parallel with the Japan trench and the Ryukyu trench and roughly coincides with a prominent surface topography and gravity boundary in East China, which is located approximately 1800 km west of the trenches. The upper mantle under East Asia has formed a big mantle wedge (BMW) above the stagnant slab. The BMW exhibits low seismic-velocity and high electrical-conductivity, which is hot and wet because of the deep dehydration reactions of the stagnant slab and the convective circulation process in the BMW. These processes lead to the upwelling of hot and wet asthenospheric materials and thinning and fracturing of the continental lithosphere, leading to the formation of the active intraplate volcanoes in East Asia. Our results also show that the active Tengchong volcano in SW China is related to the deep subduction of the Burma microplate down to the mantle transition zone and a BMW above the Burma slab. References: D. Zhao (2004) Phys. Earth Planet. Inter. 146, 3-34. J. Huang, D. Zhao (2006) J. Geophys. Res. 111, B09305. D. Zhao et al. (2009) Phys. Earth Planet. Inter. 173, 197-206.

Zhao, D.

2009-12-01

428

Agent-based models of financial markets  

NASA Astrophysics Data System (ADS)

This review deals with several microscopic ('agent-based') models of financial markets which have been studied by economists and physicists over the last decade: Kim-Markowitz, Levy-Levy-Solomon, Cont-Bouchaud, Solomon-Weisbuch, Lux-Marchesi, Donangelo-Sneppen and Solomon-Levy-Huang. After an overview of simulation approaches in financial economics, we first give a summary of the Donangelo-Sneppen model of monetary exchange and compare it with related models in economics literature. Our selective review then outlines the main ingredients of some influential early models of multi-agent dynamics in financial markets (Kim-Markowitz, Levy-Levy-Solomon). As will be seen, these contributions draw their inspiration from the complex appearance of investors' interactions in real-life markets. Their main aim is to reproduce (and, thereby, provide possible explanations) for the spectacular bubbles and crashes seen in certain historical episodes, but they lack (like almost all the work before 1998 or so) a perspective in terms of the universal statistical features of financial time series. In fact, awareness of a set of such regularities (power-law tails of the distribution of returns, temporal scaling of volatility) only gradually appeared over the nineties. With the more precise description of the formerly relatively vague characteristics (e.g. moving from the notion of fat tails to the more concrete one of a power law with index around three), it became clear that financial market dynamics give rise to some kind of universal scaling law. Showing similarities with scaling laws for other systems with many interacting sub-units, an exploration of financial markets as multi-agent systems appeared to be a natural consequence. This topic has been pursued by quite a number of contributions appearing in both the physics and economics literature since the late nineties. From the wealth of different flavours of multi-agent models that have appeared up to now, we discuss the Cont-Bouchaud, Solomon-Levy-Huang and Lux-Marchesi models. Open research questions are discussed in our concluding section.

Samanidou, E.; Zschischang, E.; Stauffer, D.; Lux, T.

2007-03-01

429

Hazard categorization for 300 area N reactor fuel fabrication and storage facility  

SciTech Connect

A final hazard categorization has been prepared for the 300 Area Fuel Supply Shutdown (FSS) facility in accordance with DOE-STD-1027-92, ''Hazard Categorization and Accident Analysis Techniques for Compliance with DOE Order 5480.23, Nuclear Safety Analysis Reports'' (DOE 1992). Prior to using the hazard category methodology, hazard classifications were prepared in accordance with the requirements of the Westinghouse Hanford Company (Westinghouse Hanford) controlled manual, WHC-CM-4-46, ''Safety Analysis Manual'', Chapter 4.0, ''Hazard Classification.'' A hazard classification (Huang 1995) was previously prepared for the FSS in accordance with WHC-CM-4-46. The analysis lead to the conclusion that the FSS should be declared a Nuclear facility with a Moderate Hazard Class rating. The analysis and results contained in the hazard classification can be used to provide additional information to support other safety analysis documentation. Also, the hazard classification provides analyses of the toxicological hazards inherent with the FSS inventory: whereas, a hazard categorization prepared in accordance with DOE-STD-1027-92, considers only the radiological component of the inventory.

Brehm, J.R., Fluor Daniel Hanford

1997-02-12

430

A time and space correlated turbulence synthesis method for Large Eddy Simulations  

NASA Astrophysics Data System (ADS)

In the present work the problem of generating synthesized turbulence at inflow boundaries of the simulation domain is addressed in the context of the Large Eddy Simulation (LES) method. To represent adequately certain statistical properties of a turbulent process, we propose a synthesized turbulence method which is based on previous works (Huang et al., 2010; Smirnov et al., 2001) [15,28]. For this purpose, time and space correlations are introduced strictly in the mathematical formulation of the synthetic turbulence inflow data. It is demonstrated that the proposed approach inherits the properties of the methods on which it is based while presents some particular advantages as well.The strategy of imposing conditions on the inlet velocity field through turbulence synthesis is implemented in the parallel multiphysics code called PETSc-FEM (http://www.cimec.org.ar/petscfem) primarily targeted to calculations throughout finite elements on general unstructured 2D and 3D grids. We present several numerical tests in order to validate and evaluate the method describing the dynamic phenomena that take place in "real-life" problems, such as a swirling turbulent flow inside a diffuser and the airflow around a vehicle model inside a wind tunnel at high Reynolds number.

Castro, Hugo G.; Paz, Rodrigo R.

2013-02-01

431

The Rotational Spectra of the Silicon Isotopic Species of SiCC  

NASA Astrophysics Data System (ADS)

Until this work, the rotational spectra of the silicon isotopic species of SiCC were based almost entirely on astronomical frequencies, because only the fundamental 1_{0,1} - 0_{0,0} transition ^{29}SiC_2 and ^{30}SiC_2 had been measured in the laboratory. We have now derived precise rotational and centrifugal distortion constants from laboratory measurements of 35 transitions of each isotopic species between 140 and 360 GHz with J ? 10 and K_a ? 8. The rotational spectra calculated with the laboratory measured constants are about two orders of magnitude more accurate than that of He et al., who determined the spectroscopic constants from about 20 lines of ^{29}SiC_2 and of ^{30}SiC_2 in the wide-line source IRC+10216. The new laboratory measurements should aid assignment of the silicon isotopic species of SiCC in the spectral line survey of IRC+10216 with the SMA, and in future observations with ALMA. R. D. Suenram, F. J. Lovas, and K. Matsumura, Astrophys. Journ. Lett. 342, L103 (1989) J. H. He, Dinh-V-Trung, S. Kwok, H. S. P. Müller, Y. Zhang, T. Hasegawa, T. C. Peng, and Y. C. Huang, Astrophys. Journ. Suppl. Ser., 177, 275 (2008). N. A. Patel, K. H. Young, S. Brünken, R. W. Wilson, P. Thaddeus, K. M. Menten, M. Reid, M. C. McCarthy, Dinh-V-Trung, C. A. Gottlieb, and A. Hedden, Astrophys. Journ., in press (2009).

Kokkin, Damian L.; Gottlieb, Carl A.; McCarthy, Michael. C.; Thaddeus, Patrick; Brünken, Sandra

2009-06-01

432

A Rank-Based Test for Comparison of Multidimensional Outcomes.  

PubMed

For comparison of multiple outcomes commonly encountered in biomedical research, Huang et al. (2005) improved O'Brien's (1984) rank-sum tests through the replacement of the ad hoc variance by the asymptotic variance of the test statistics. The improved tests control the Type I error rate at the desired level and gain power when the differences between the two comparison groups in each outcome variable fall into the same direction. However, they may lose power when the differences are in different directions (e.g., some are positive and some are negative). These tests and the popular Bonferroni correction failed to show important significant difference when applied to compare heart rates from a clinical trial to evaluate the effect of a procedure to remove the cardioprotective solution HTK. We propose an alternative test statistic, taking the maximum of the individual rank-sum statistics, which controls the type I error and maintains satisfactory power regardless of the directions of the differences. Simulation studies show the proposed test to be of higher power than other tests in certain alternative parameter space of interest. Furthermore, when used to analyze the heart rates data the proposed test yields more satisfactory results. PMID:21625372

Liu, Aiyi; Li, Qizhai; Liu, Chunling; Yu, Kai; Yu, Kai F

2010-06-01

433

A Rank-Based Test for Comparison of Multidimensional Outcomes  

PubMed Central

For comparison of multiple outcomes commonly encountered in biomedical research, Huang et al. (2005) improved O’Brien’s (1984) rank-sum tests through the replacement of the ad hoc variance by the asymptotic variance of the test statistics. The improved tests control the Type I error rate at the desired level and gain power when the differences between the two comparison groups in each outcome variable fall into the same direction. However, they may lose power when the differences are in different directions (e.g., some are positive and some are negative). These tests and the popular Bonferroni correction failed to show important significant difference when applied to compare heart rates from a clinical trial to evaluate the effect of a procedure to remove the cardioprotective solution HTK. We propose an alternative test statistic, taking the maximum of the individual rank-sum statistics, which controls the type I error and maintains satisfactory power regardless of the directions of the differences. Simulation studies show the proposed test to be of higher power than other tests in certain alternative parameter space of interest. Furthermore, when used to analyze the heart rates data the proposed test yields more satisfactory results.

Liu, Aiyi; Li, Qizhai; Liu, Chunling; Yu, Kai; Yu, Kai F.

2011-01-01

434

IRS Observation of IR luminous LBGs  

NASA Astrophysics Data System (ADS)

Lyman-Break Galaxies (LBGs) and Submillimeter Galaxies (SMGs) are star-forming galaxies at high-redshifts, selected in very different ways. A large amount of spectroscopic data are now available for LBGs, and consequently we have an increasingly meaninful understanding of their physical properties. By contrast SMGs (i.e., high-redshift ULIRGs) are notoriously faint and difficult to identify at visible wavelengths, making it extremely hard even to measure their redshifts. However, we have recently discovered (Huang etal 2005) a population that links LBGs and SMGs: Infrared-Luminous Lyman Break Galaxies (ILLBGs). ILLBGs strongly resemble SMGs in the infrared, yet are surprisingly bright at visible wavelengths. This permits 1.) high S/N study of their rest-frame UV spectra, 2.) measurement of differences in physical properties between normal blue LBGs and ILLBGs, and 3.) comparison of ILLBGs to their local ULIRG/LIRG couterparts. We have recently completed a new, large photometric survey for LBGs in the Extended Groth Strip (EGS) field, in which we detected 6500 LBG candidates. Amoung these, 220 have clear detections in the MIPS 24 micron band -- in other words, they are ILLBGs. This is the largest ULIRG/LIRG sample at z=3 in existence. We ask for four nights of GMOS time to carry out a spectroscopic study of this important population that links LBGs and SMGs.

Fazio, Giovanni; Huang, Jiasheng; Ashby, Matt; Marcillac, Delphine; Papovich, Casey; Rigopoulou, Dimitra; Webb, Tracy; Willner, Steve; Yan, Lin

2007-05-01

435

Dusty Dwarfs in the Local Universe  

NASA Astrophysics Data System (ADS)

We present Spitzer observations of a complete sample of low mass, low metallicity, star-forming dwarf galaxies. These galaxies were selected from the KPNO International Spectroscopic Survey in the Boötes field. The galaxies are found to span a wide range of mid-infrared properties and, contrary to expectations, all of the galaxies show significant dust emission in the mid-infrared. This emission is much better correlated with star-formation rate than it is with metallicity or the optical reddening. We present the mid-infrared properties of the galaxies and the SEDs. An unexpected outcome of our study is the discovery that local star-forming dwarf galaxies have stellar masses and infrared colors similar to those of a subsample of z=3 Lyman Break galaxies (LBGs; Huang etal 2006, in press). The implication is that some of the Lyman-break galaxies may be the low mass, low metallicity systems that are the building blocks of the galaxies that we see today. This work has been supported through NASA Spitzer contract 1407, NSF/AST-0302049, NSF/AST 95-53020, NSF/AST 00-71114, and NSF/AST 03-07766.

Rosenberg, J. L.; Ashby, M. L. N.; Salzer, J. J.; Huang, J.-S.

2005-12-01

436

Triggering the Growth of Large Single Crystal Graphene by Chemical Vapor Deposition  

NASA Astrophysics Data System (ADS)

Graphene, a monolayer of sp2 carbon atoms, has been attracting great interests as an ideal two dimensional crystalline material. Fabrication technique for wafer scale graphene via chemical vapor deposition (CVD) was developed several years ago [1]. However, large scale graphene films from CVD method so far are found to be polycrystalline, consisting of numerous grain boundaries, which greatly degrade the electrical and mechanical properties of graphene [2]. Recently, we obtained hexagonal-shaped single-crystal monolayer graphene domains (˜1.2 mm) [3]. We adapted a strategy to synthesize larger size single crystal grains by regulating the supply of reactants and hytrogen. Nucleation density can be decreased to less than 1000 nuclei /m2. Gradually increase in the supply of reactants could break the equilibrium of growth and etching at the edge of hexagonal-shaped graphene grains. It drives the reaction toward quick growth of graphene domains during the whole CVD process. The graphene grains we obtained show high crystalline quality with high mobility of ˜13000 cm2V-1s-1, which is comparable to that of exfoliated graphene. The results achieved will definitely benefit for further practical application of graphene electronics. [1] Li X S, et al. Science, 2009, 324: 1312˜1314. [2] Huang PY, et al. Nature 2011, 469: 389-392. [3] Wu T R, et al. Adv. Func. Mater. 2012, Doi: 10.1002/adfm.201201577.

Wu, Tianru; Wang, Haomin; Ding, Guqiao; Jiang, Da; Xie, Xiaoming; Jiang, Mianheng

2013-03-01

437

Observation of low-frequency oscillations in LDX with an angular electrostatic probe  

NASA Astrophysics Data System (ADS)

Previous computational models using magnetic configurations similar to LDX have yielded results where convective cells transport particles without transporting energy [1], and this would prove useful in a fusion reactor since it could remove ash from the core without cooling it. A vertically adjustable angular electrostatic probe array has been designed to observe the previously seen low-frequency oscillations [2] with better resolution and to identify if they are related to the expected convective cells. The array will rest one meter from the centerline of the device and measure edge fluctuations on field lines near the separatrix that are mapped to 1.7m to 1.85m at midplane. It will cover ninety degrees angularly and have 24 probes mounted on it for total probe tip separation of 7.1cm. Each probe will consist of a 1cm tungsten electrode inside an alumina tube in series with a one mega-ohm resistor located 50 cm from the probe tip. The array can be fitted with an extension to provide radial sampling at a later date. [0pt] [1] J. Tonge, N. Leboeuf, C. Huang, and J.M. Dawson Phys. Plasmas 10 (2003) 9.[0pt] [2] D. Garnier et al., J. Plasma Phys. 74 (2008).

Bergmann, R. M.; Boxer, A. C.; Ellsworth, J. L.; Kesner, J.; Garnier, D. T.; Mauel, M. E.

2008-11-01

438

The Effect of Bottom Curvature on Mudflow Dynamics: Theory and Experiments  

NASA Astrophysics Data System (ADS)

A one-dimensional mathematical model of mudflow dynamics is formulated assuming mud to behave rheologically as a Herschel-Bulkley fluid. Novel features of the present contribution regard the propagation of mud-flows over a curvilinear bottom. A set of nonlinear partial differential equations is found to govern the unsteady, non-uniform flow of such fluids. Following the approach of Huang and Garcia [1998], depth-integrated forms of the continuity equation, as well as shear-integrated and plug-integrated forms of the momentum equations are derived. A perturbation analysis is also carried out under the assumption of 'slender' flow. The leading order problem takes the form of a kinematic wave equation. A free oscillating numerical solution of this hyperbolic conservative equation is obtained using the flux corrected transport (FCT) method. Characteristics and run out distances of the mud-flow are studied. The effects of bottom curvature on mud-flow dynamics is analyzed. Experiments are performed releasing a given volume of Kaoline and water mixture from a reservoir into an upward concave wide channel. Comparison between the numerical solution and the experimental data are generally satisfactory, though suggesting limitations typical of any approach which neglect convective accelerations.

Siviglia, A.; Cantelli, A.

2004-12-01

439

Effect of bottom curvature on mudflow dynamics: Theory and experiments  

NASA Astrophysics Data System (ADS)

A one-dimensional mathematical model of mudflow dynamics is formulated assuming mud to behave rheologically as a Herschel-Bulkley fluid. Novel features of the present contribution regard the propagation of mudflows over a curvilinear bottom. A set of nonlinear partial differential equations is found to govern the unsteady, nonuniform flow of such fluids. Following the approach of Huang and Garcìa (1998), a depth-integrated form of the continuity equation and shear-integrated and plug-integrated forms of the momentum equations are derived. A perturbation analysis is also carried out under the assumption of "slender" flow. The leading-order problem takes the form of a kinematic wave equation. One straightforward application of this simplified model is the evaluation of the maximum run-out extension of a mud which flows over a bed with a variable topography. This solution is obtained by solving the steady state problem. Dynamics information are obtained by numerically solving the hyperbolic conservative equation by means of a free oscillating numerical method. The effects of bottom curvature either on the equilibrium solution or mudflow dynamics are analyzed. Experiments are also performed releasing a given volume of kaoline and water mixture from a reservoir into both a constant slope and an upward concave channel. Comparisons between the numerical solution and the experimental data are generally satisfactory, though suggesting limitations typical of any approach that neglects convective accelerations and assumes gradually varied flow.

Siviglia, A.; Cantelli, A.

2005-11-01

440

Nonparametric modeling of longitudinal covariance structure in functional mapping of quantitative trait loci.  

PubMed

Estimation of the covariance structure of longitudinal processes is a fundamental prerequisite for the practical deployment of functional mapping designed to study the genetic regulation and network of quantitative variation in dynamic complex traits. We present a nonparametric approach for estimating the covariance structure of a quantitative trait measured repeatedly at a series of time points. Specifically, we adopt Huang et al.'s (2006, Biometrika 93, 85-98) approach of invoking the modified Cholesky decomposition and converting the problem into modeling a sequence of regressions of responses. A regularized covariance estimator is obtained using a normal penalized likelihood with an L(2) penalty. This approach, embedded within a mixture likelihood framework, leads to enhanced accuracy, precision, and flexibility of functional mapping while preserving its biological relevance. Simulation studies are performed to reveal the statistical properties and advantages of the proposed method. A real example from a mouse genome project is analyzed to illustrate the utilization of the methodology. The new method will provide a useful tool for genome-wide scanning for the existence and distribution of quantitative trait loci underlying a dynamic trait important to agriculture, biology, and health sciences. PMID:19302406

Yap, John Stephen; Fan, Jianqing; Wu, Rongling

2009-12-01

441

Magnetostratigraphic age of the Xiantai Paleolithic site in the Nihewan Basin and implications for early human colonization of Northeast Asia  

NASA Astrophysics Data System (ADS)

Timing of the early habitation and stone technologies in the Nihewan Basin, North China has provided insights into our understanding of early human adaptability to high northern latitudes in East Asia. Here we contribute to this topic with detailed magnetostratigraphic investigation, coupled with mineral magnetic measurements and palynological analyses on a lacustrine sequence in this basin, which contains the Xiantai Paleolithic site. Magnetite and hematite were identified as the main carriers for the characteristic remanent magnetizations. Magnetostratigraphic results show that the Xiantai lacustrine sequence recorded the Brunhes chron, the Jaramillo and the Olduvai subchrons, and successive reverse polarity portions of the intervening Matuyama chron. Stratigraphic correlation in terms of lithology, magnetic susceptibility and magnetic polarity sequences between the Xiantai and Xiaochangliang sections indicates that the Xiantai artefact layer is readily contemporary with the Xiaochangliang artefact layer, which has been previously estimated to be about 1.36 Ma [R.X. Zhu, K.A. Hoffman, R. Potts, C.L. Deng, Y.X. Pan, B. Guo, C.D. Shi, Z.T. Guo, B.Y. Yuan, Y.M. Hou, W.W. Huang, Earliest presence of humans in northeast Asia, Nature 413 (2001) 413-417.]. Early humans of the Xiantai Paleolithic site lived in a steppe paleoenvironment indicated from fossil pollens. Furthermore, the combined evidence of our magnetostratigraphy and previously published magnetochronology and paleoclimate data documents that early humans of North China were able to adjust to an increasing variability of paleoclimates and paleoenvironments over the Early Pleistocene.

Deng, Chenglong; Wei, Qi; Zhu, Rixiang; Wang, Hongqiang; Zhang, Rui; Ao, Hong; Chang, Liao; Pan, Yongxin

2006-04-01

442

Vibrational wave packet induced oscillations in two-dimensional electronic spectra. II. Theory  

NASA Astrophysics Data System (ADS)

We present a theory of vibrational modulation of two-dimensional coherent Fourier transformed electronic spectra. Based on an expansion of the system's energy gap correlation function in terms of Huang-Rhys factors, we explain the time-dependent oscillatory behavior of the absorptive and dispersive parts of two-dimensional spectra of a two-level electronic system, weakly coupled to intramolecular vibrational modes. The theory predicts oscillations in the relative amplitudes of the rephasing and nonrephasing parts of the two-dimensional spectra, and enables to analyze time-dependent two-dimensional spectra in terms of simple elementary components whose line shapes are dictated by the interaction of the system with the solvent only. The theory is applicable to both low and high energy (with respect to solvent induced line broadening) vibrations. The results of this paper enable to qualitatively explain experimental observations on low energy vibrations presented in the preceding paper [A. Nemeth et al., J. Chem. Phys. 132, 184514 (2010)] and to predict the time evolution of two-dimensional spectra in ultrafast ultrabroadband experiments on systems with high energy vibrations.

Man?al, Tomáš; Nemeth, Alexandra; Milota, Franz; Lukeš, Vladimír; Kauffmann, Harald F.; Sperling, Jaroslaw

2010-05-01

443

Complexity of the Taskless Mind at Different Time-Scales: an Empirically Weighted Approach to Decomposition and Measurement  

NASA Astrophysics Data System (ADS)

The neurodynamical state of an eyes closed at `rest' subject is an area of keen interest in the neuroscience community due to Raichle's field changing concept of the Default Mode Network [1]. The dynamic analysis of neurobiologically derived data commonly involves the computation of distributional measures and time-frequency transforms, and more recently the use of ergodic measures. However, many of the methods used in these computations rely upon questionable assumptions such as stationarity or approximate linearity. The Empirical Mode Decomposition of Huang et al.., [2], which preserves nonlinearity and non-stationarity, has led to alternative signal processing techniques. We append to this growing set of techniques a well-defined class of Weighting Functionals, WF. The strength is that they are easily applied to any number of time-frequency transforms and ergodic/complexity measurements because the WFs rescale all the results according to the proportion of energy contained at the individual time-scales. The application to er-godic/complexity measurements has not been addressed in the context of Intrinsic Mode Functions, and is done so here for the first time. Our interest is to take these methods and demonstrate time dependence of the signal across multiple time-scales in the comparison of normal controls and a variety of psychopathological and neuropathological conditions.

Aven, John L.; Mandell, Arnold J.; Holroyd, Tom; Coppola, Richard

2011-04-01

444

Calculation of beam loading and particle trapping using a quasistatic simulation code  

NASA Astrophysics Data System (ADS)

Plasma based particle acceleration requires the generation of plasma wave wakes which maintain their coherence over long distances. For example in Laser Wake Field Acceleration (LWFA) schemes the laser pulse must propagate tens of centimeters, which corresponds to many Rayleigh lengths, and in Plasma Wake Field Acceleration (PWFA) the particle beam must be propagated many meters. These wakes, and their effect on the driver (Laser or particle beam) can be simulated efficiently in the quasistatic approximation [1,2]. In this approximation the driver does not evolve during the time a plasma electron spends in the driver. Particles that are trapped in the wake must be treated by an alternate algorithm. Here we modify the 2D code WAKE [1] to treat such particles. We also implement an algorithm that allows for plasma particle to become trapped particles if they gain sufficient energy. Similar implementations have been made in the 3D code QUICKPIC [2]. These changes in WAKE will give users a tool that can be used on a desk-top machine to simulated GeV acceleration. [1] P. Mora and T. M. Antonsen Jr., Phys Plasma 4, 217 (1997) [2] C. Huang et al., J. Comp Phys., to be published.

Morshed, Sepehr; Antonsen, Thomas; Huang, Chengkun; Mori, Warren

2006-10-01

445

Misalignment diagnosis of rotating machinery through vibration analysis via the hybrid EEMD and EMD approach  

NASA Astrophysics Data System (ADS)

The objective of this research is to investigate the feasibility of utilizing the hybrid method of ensemble empirical mode decomposition (EEMD) and pure empirical mode decomposition (EMD) to efficiently decompose the complicated vibration signals of rotating machinery into a finite number of intrinsic mode functions (IMFs), so that the fault characteristics of the misaligned shaft can be examined in the time-frequency Hilbert spectrum as well as the marginal Hilbert spectrum. The intrawave frequency modulation (FM) phenomenon, which indicates the nonlinear vibration behavior of a misaligned shaft, can be observed in the time-frequency Hilbert spectrum through the Hilbert-Huang transform (HHT) technique. The fault characteristic of shaft misalignment is also featured in terms of the amplitude modulation (AM) phenomenon in the information-containing IMF components that are extracted by the significance test. Through performing the envelope analysis on the information-containing IMF, the marginal Hilbert spectrum of the envelope signal of this IMF component exhibits that the level of shaft misalignment is presented by the level of AM in the IMF. A test bed of a rotor-bearing system is performed experimentally to illustrate both the parallel and angular shaft misalignment conditions as well as the healthy condition. The analysis results show that the proposed approach is capable of diagnosing the misaligned fault of the shaft in rotating machinery and providing a more meaningful physical insight compared with the conventional methods.

Wu, T. Y.; Chung, Y. L.

2009-09-01

446

Arterial stiffness using radial arterial waveforms measured at the wrist as an indicator of diabetic control in the elderly.  

PubMed

Although current technique of photoplethysmography (PPG) is a popular noninvasive method of waveform contour analysis in assessing arterial stiffness, data obtained are frequently affected by various environmental and physiological factors. We proposed an easily operable air pressure sensing system (APSS) for radial arterial signal capturing. Totally, 108 subjects (young, the aged with or without diabetes) were recruited from July 2009 to May 2010. Arterial waveform signals from the wrist were obtained and analyzed using Hilbert-Huang transformation (HHT). Through ensemble empirical mode decomposition (EEMD), the signals were decomposed into eight intrinsic mode functions (IMF1-8) of which IMF5 was found to be the desired signal with a discernible diastolic peak. The results showed significant differences in reflection index (RI) and stiffness index (SI) from the young subjects and those from the aged participants with or without diabetes. Significant differences in RI and SI were also noted between subjects with well-controlled diabetes and those without. Good reproducibility and correlation were demonstrated. In conclusion, the present study proposed the application of radial arterial signal capturing subsystem and HHT in acquiring more reliable data on RI and SI compared with the conventional PPG method. PMID:20923726

Wu, Hsien-Tsai; Lee, Chun-Ho; Liu, An-Bang; Chung, Wei-Sheng; Tang, Chieh-Ju; Sun, Cheuk-Kwan; Yip, Hon-Kan

2010-10-04

447

Comparing the applications of EMD and EEMD on time-frequency analysis of seismic signal  

NASA Astrophysics Data System (ADS)

The Hilbert-Huang transform (HHT) is a novel signal analysis method in seismic exploration. It integrates empirical mode decomposition (EMD) and classical Hilbert transform (HT), which can express the intrinsic essence using simple and understandable algorithm. But there is a serious mode mixing phenomenon in EMD. To solve the mode mixing problem, a noise-assisted data analysis method called ensemble empirical mode decomposition (EEMD) is adopted instead of EMD. In this paper, the applications of EMD and EEMD on time-frequency analyzing behaviors were compared, and the results show that (1) EMD decomposes an original nonlinear and non-stationary signal into a series of simple intrinsic mode functions (IMFs), but with the mode mixing phenomenon. (2) EEMD skillfully solves the mode mixing problem by adding a white noise to the original signal. (3) The synthetic signal example reveals the remarkable ability of EEMD to decompose the signal into different IMFs and analyze the time-frequency distribution of the signal. (4) The time-frequency spectrum obtained by EEMD more realistically reflects the real geology than by EMD.

Wang, Tong; Zhang, Mingcai; Yu, Qihao; Zhang, Huyuan

2012-08-01

448

Potential contrast improvement in ultrasound pulse inversion imaging using EMD and EEMD.  

PubMed

Ultrasound nonlinear imaging using microbubble-based contrast agents has been widely investigated. Nonetheless, its contrast is often reduced by the nonlinearity of acoustic wave propagation in tissue. In this paper, we explore the use of empirical mode decomposition (EMD) and ensemble empirical mode decomposition (EEMD) in the Hilbert-Huang transform (HHT) for possible contrast improvement. The HHT is designed for analyzing nonlinear and nonstationary data, whereas EMD is a method associated with the HHT that allows decomposition of data into a finite number of intrinsic modes. The hypothesis is that the nonlinear signal from microbubbles and the tissue nonlinear signal can be better differentiated with EMD and EEMD, thus making contrast improvement possible. Specifically, we tested this method on pulse-inversion nonlinear imaging, which is generally regarded as one of the most effective nonlinear imaging methods. The results show that the contrast-to-tissue ratios at the fundamental and second-harmonic frequencies were improved by 10.2 and 4.3 dB, respectively, after EEMD. Nonetheless, image artifacts also appeared, and hence further investigation is needed before EMD and EEMD can be applied in practical applications of ultrasound nonlinear imaging. PMID:20178898

Liao, Ai-Ho; Shen, Che-Chou; Li, Pai-Chi

2010-01-01

449

Fault diagnosis of rotating machinery using an improved HHT based on EEMD and sensitive IMFs  

NASA Astrophysics Data System (ADS)

A Hilbert-Huang transform (HHT) is a time-frequency technique and has been widely applied to analyzing vibration signals in the field of fault diagnosis of rotating machinery. It analyzes the vibration signals using intrinsic mode functions (IMFs) extracted using empirical mode decomposition (EMD). However, EMD sometimes cannot reveal the signal characteristics accurately because of the problem of mode mixing. Ensemble empirical mode decomposition (EEMD) was developed recently to alleviate this problem. The IMFs generated by EEMD have different sensitivity to faults. Some IMFs are sensitive and closely related to the faults but others are irrelevant. To enhance the accuracy of the HHT in fault diagnosis of rotating machinery, an improved HHT based on EEMD and sensitive IMFs is proposed in this paper. Simulated signals demonstrate the effectiveness of the improved HHT in diagnosing the faults of rotating machinery. Finally, the improved HHT is applied to diagnosing an early rub-impact fault of a heavy oil catalytic cracking machine set, and the application results prove that the improved HHT is superior to the HHT based on all IMFs of EMD.

Lei, Yaguo; Zuo, Ming J.

2009-12-01

450

Automatic contrast enhancement using ensemble empirical mode decomposition.  

PubMed

Ultrasound nonlinear contrast imaging using microbubble-based contrast agents has been widely investigated. However, the degree of contrast enhancement is often limited by overlap between the spectra of the tissue and microbubble nonlinear responses, which makes it difficult to separate them. The use of ensemble empirical mode decomposition (EEMD) in the Hilbert-Huang transform (HHT) was previously explored with the aim of alleviating this problem. The HHT is designed for analyzing nonlinear and nonstationary data, whereas EEMD is a method associated with the HHT that allows decomposition of data into a finite number of intrinsic mode functions (IMFs). It was found that the contrast can be effectively improved in certain IMFs, but manual selection of appropriate IMFs is still required. This prompted the present study to test the hypothesis that the contrast can be enhanced without requiring manual selection by summing appropriately weighted IMFs and demodulating the signal at appropriate frequencies. That is, a data-driven mechanism for determining weights and demodulation frequencies was derived and tested. Phantom results show that an overall contrast enhancement of up to 12.5 dB can be achieved. A fused-image representation that simultaneously displays the conventional B-mode image and the new contrast-mode image is also presented. PMID:23443703

Lin, Shang-Ching; Li, Pai-Chi

2011-12-01

451

Spatial Patterning of Newly-Inserted Material during Bacterial Cell Growth  

NASA Astrophysics Data System (ADS)

In the life cycle of a bacterium, rudimentary microscopy demonstrates that cell growth and elongation are essential characteristics of cellular reproduction. The peptidoglycan cell wall is the main load-bearing structure that determines both cell shape and overall size. However, simple imaging of cellular growth gives no indication of the spatial patterning nor mechanism by which material is being incorporated into the pre-existing cell wall. We employ a combination of high-resolution pulse-chase fluorescence microscopy, 3D computational microscopy, and detailed mechanistic simulations to explore how spatial patterning results in uniform growth and maintenance of cell shape. We show that growth is happening in discrete bursts randomly distributed over the cell surface, with a well-defined mean size and average rate. We further use these techniques to explore the effects of division and cell wall disrupting antibiotics, like cephalexin and A22, respectively, on the patterning of cell wall growth in E. coli. Finally, we explore the spatial correlation between presence of the bacterial actin-like cytoskeletal protein, MreB, and local cell wall growth. Together these techniques form a powerful method for exploring the detailed dynamics and involvement of antibiotics and cell wall-associated proteins in bacterial cell growth.[4pt] In collaboration with Kerwyn Huang, Stanford University.

Ursell, Tristan

2012-02-01

452

Surface Deformation and Seismic Rebound: Implications and Applications  

NASA Astrophysics Data System (ADS)

An earthquake process includes pre-seismic stress accumulation, co-seismic rock rupture and post-seismic elastic and/or viscoelastic rebound. Although co-seismic and post-seismic deformations have been readily observed using the global positioning system (GPS), detecting pre-seismic stress accumulation hidden in time-series data remains challenging. This study applies the Hilbert-Huang transform to extract non-linear and non-stationary pre-earthquake deformation data from GPS records for central Taiwan. By converting the derived surface deformation into horizontal azimuths, the randomly oriented GPS-azimuths are reoriented in a similar direction several days before and after earthquakes due to loading and rebound stress, respectively. Analytical results demonstrate that the stress accumulation and release along the entire course of an earthquake process provide significant evidence supporting the seismic rebound theory. This finding would be applicable to areas with dense GPS networks and active plate interactions. Surface deformations detected by the proposed analytical technique have encouraging potential for mitigating future seismic hazards.

Chen, Chieh-Hung; Yeh, Ta-Kang; Liu, Jann-Yenq; Wang, Chung-Ho; Wen, Strong; Yen, Horng-Yuan; Chang, Shu-Hao

2011-05-01

453

Molecular biological characteristics based Hierarchical Mumford-Shah Vector-Model for the delineation of biological target volumes corresponding to head and neck tumors.  

PubMed

To more accurately and precisely delineate a biologic target volume (BTV) for the positron emission tomography (PET)-guided radiotherapy treatment planning, we proposed a novel Hierarchical Mumford-Shah Vector Model (HMSMv), where the image-vector was composed of the molecular biological characteristics such as contrast, busyness and the standard uptake value (SUV) of tumors. The BTV was delineated via the propagation of the level set flow of the proposed HMSMv. The propagation took place inside a ring-volume of interest (VOI) which was defined by an adaptive volume-growing algorithm based on the PET SUV, contrast and busyness of a tumor. Four patient studies were assessed and visually inspected by two radiation oncologists (Suyu Zhu and Zaijie Huang). Compared the resulting BTV with the gross target volume (GTV) of one patient study, the sensitivity, specificity and similarity were 92.28%, 87.29%, 79.28% respectively. Moreover, all of four BTVs were between the corresponding GTV and planning target volume (PTV). Most of the BTVs were between the GTV and the clinical target volume (CTV). The results demonstrated that the proposed method can delineate the BTVs of nasopharyngeal carcinomas more accurately and precisely than the manual delineation and also the threshold segmentation method with SUV of 2.5 as the threshold. The GTV, CTV, and PTV were manually delineated by the two radiation oncologists based on PET, CT and MRI images for the intensity modulated radiotherapy (IMRT) planning of the four patients. PMID:24110442

Liu, Guocai; Yang, Weili; Zhu, Suyu; Huang, Qiu; Huang, Zaijie; Wu, Haiyan; Liu, Min; Huang, Wenlin; Liu, Bin; Liu, Jinguang; Hu, Bingqiang; Mo, Yi; Zhang, Jiutang; Zeng, Biao; Yuan, Yuan; Peng, Xiang; Liu, Ke; Zhou, Jumei

2013-07-01

454

The tensor structure on the representation category of the {W}_p triplet algebra  

NASA Astrophysics Data System (ADS)

We study the braided monoidal structure that the fusion product induces on the Abelian category {W}_p-mod, the category of representations of the triplet W-algebra {W}_p. The {W}_p-algebras are a family of vertex operator algebras that form the simplest known examples of symmetry algebras of logarithmic conformal field theories. We formalize the methods for computing fusion products, developed by Nahm, Gaberdiel and Kausch, that are widely used in the physics literature and illustrate a systematic approach to calculating fusion products in non-semi-simple representation categories. We apply these methods to the braided monoidal structure of {W}_p-mod, previously constructed by Huang, Lepowsky and Zhang, to prove that this braided monoidal structure is rigid. The rigidity of {W}_p-mod allows us to prove explicit formulae for the fusion product on the set of all simple and all projective {W}_p-modules, which were first conjectured by Fuchs, Hwang, Semikhatov and Tipunin; and Gaberdiel and Runkel.

Tsuchiya, Akihiro; Wood, Simon

2013-11-01

455

Nonradial Pulsation Mode-Typing of 53 Per from the Far-UV  

NASA Astrophysics Data System (ADS)

Voyager 2 (FUV) spectroscopic observations during January 1991 have been obtained and compared with coterminous optical photometric observations by Huang et al. (1994, ApJ, in press). The ephemeris derived from the optical light curve shows a two-mode solution with frequencies of 0.462 and 0.233 cy d(-1) . These frequencies are also in good agreement with frequencies derived for 53 Per in the late 1970's and mid-1980's. The FUV results show excellent agreement with the FUV light (1180 Angstroms) and color (1180 Angstroms - 1585 Angstroms) curves. The UV/visual amplitude implied is 4.6+/-1. On the assumption that the optical and UV periods arise from nonradial pulsation (NRP) modes, we compare our UV amplitudes with those obtained by linear NRP theory. To make this comparison we have computed wavelength-dependent, limb-darkening integrals from metal line blanketed model atmospheres and used them to evaluate the sources of light variations. We find that the effects of temperature on these modes should be dominant, a prediction verified by the new UV data. We also derive a modal identification l = 2 for the principal mode.

Huang, L.; Smith, M. A.

1993-12-01

456

Does inhibition of poly(ADP-ribose) polymerase prevent energy overconsumption under microgravity?  

NASA Astrophysics Data System (ADS)

When plants are exposed to a stress signal they expend a lot of energy and exhibit enhanced respiration rates This is partially due to a breakdown in the NAD pool caused by the enhanced activity PARP which uses NAD as a substrate to synthesize polymers of ADP-ribose Stress-induced depletion of NAD results in a similar depletion of energy since ATP molecules are required to resynthesize the depleted NAD It seems that plants with lowered poly ADP ribosyl ation activity appear tolerant to multiple stresses Inhibiting PARP activity prevents energy overconsumption under stress allowing normal mitochondrial respiration We intend to study if the microgravity is perceived by plants as a stress factor and if experimental inhibition of poly ADP-ribose polymerase may improve the energetic level of the cells References DeBlock M Verduyn C De Brouwer D and Cornelissen M 2005 Poly ADP-ribose polymerase in plants affects energy homeostasis cell death and stress tolerance The Plant Journal 41 95--106 Huang S Greenway H Colmerm T D and Millar A H 2005 Protein synthesis by rice coleoptiles during prolonged anoxia Implications for glycolysis growth and energy utilization Annals of Botany 96 703--715 Mittler R Vanderauwera S Gollery M and Van Breusegem F 2005 Reactive oxygen gene network of plants Trends in Plant Science 9 10 490-498

Dobrota, C.; Piso, M. I.; Keul, A.

457

Preserving electron spin coherence by dynamical decoupling based on Nitrogen-Vacancy center in diamond  

NASA Astrophysics Data System (ADS)

To exploit the quantum coherence of electron spins in solids in future technologies such as quantum manipulating, it's first vital to overcome the problem of spin decoherence due to their coupling the noisy environment. Dynamical decoupling is a particularly promising strategy for combating decoherence. I will briefly introduce the roadmap for dynamical decoupling and show our experimental research on the field in detail. We first applied the optimal dynamical decoupling scheme [1] on electron spins of ensemble sample [2]. Based on the technology, the dynamical decoupling sequence was used to observe the anomalous coherence effect and of single electron spin based on nitrogen-vacancy defect center in diamond [3]. For application, combined the dynamical decoupling together with quantum metrology protocol, the phase estimation was enhanced [4]. Instead of pulsed model, continuous dynamical decoupling was realized in our experiment and applied to protect quantum gate [5]. The next step, we will apply multi flip pulses to enhance the magnetic field sensitivity of NV center towards to the micro-scale magnetic resonance and single molecular imaging. [1] G. S. Uhrig, Phys. Rev. Lett. 98, 100504 (2007) [2] J. Du, et al., Nature 461, 1265 (2009) [3] P. Huang, et al., Nature Communications, 2, 570 (2011) [4] X. Rong, et al., Europhys. Lett. 95, 60005 (2011) [5] X. Xu, et al., Phys. Rev. Lett. 109, 070502 (2012)

Du, Jiangfeng

2013-03-01

458

Positron driven plasma wakefields  

NASA Astrophysics Data System (ADS)

The LHC is producing high-energy, high-charge proton bunches (1e11 protons at 1-7 TeV each) that could be used to accelerate ``witness'' electron bunches to TeV range eneregies via a plasma wakefield accelerator (PWFA). Simulations [1] suggest that a proton ``drive'' bunch is able to excite large wakefields if the bunch size is on the order of 100 ?m; however, the LHC paramters are currently on the 1 cm scale. SLAC'S FACET is able to supply positorn bunchs with the ideal parameters for driving a PWFA. Although at lower energy (2e10 positrons at 23 GeV each), initial simiulations in QuickPIC show that the physics of a positron drive bunch is very similar to that of a proton drive bunch. Differences in the physics arise from the mass difference: slower dephasing but faster transverse bunch evolution. Other considerations include driver head erosion and purity of the wakefield ion column. The physics of positive drivers for PWFA and the viability of this scheme for future high-energy colliders will be investigated at SLAC's FACET.[4pt] [1] Caldwell, et al. Nature Physics 5, 363 (2009).[0pt] [2] C.H. Huang, et al., J. Comp. Phys., 217(2), 658, (2006).

Pinkerton, S.; Shi, Y.; Huang, C.; An, W.; Mori, W. B.; Muggli, P.

2010-11-01

459

Pharmacological characteristics of Kampo medicine as a mixture of constituents and ingredients.  

PubMed

Herbal medicine in Japan is termed as Kampo medicine, which is derived from traditional Chinese medicine. Shakuyakukanzoto (Shao-Yao-Gan-Cao-Tang) as a kind of Kampo formulations is composed of just two components; Paeoniae Radix and Glycyrrhizae Radix, which produced marked relaxation of intestinal tract. Mokuboito (Mu-Fang-Ji-Tang) inhibited cardiac ionic channel currents, and as a mixture also produced great vasodilatation. Sinomenine (a main ingredient of Mokuboito) as a single compound also caused the vasodilatation, but decreased it along with ageing. Gypsum containing in Mokuboito and Chotosan (Diao-Teng-San) caused more marked effects, as compared with those without Gypsum. On the other hand, Rokumigan (Liu-Wei-Wan), Hachimijiogan (Ba-Wei-Di-Huang-Wan) and Goshajinkigan (Niu-Che-Shen-Qi-Wan) increase in order the number of contained ingredients. The formulations with more herbs (ingredients) produced much more effective actions on rat aorta, presumably due to compensation of the decline of pharmacological sensitivity with ageing. Thus, there are some important differences between single chemical drugs and mixture drugs with many ingredients. The effects of Kampo medicine (mixture) are never just a sum of each effect induced by a