Sample records for undergraduate biochemistry laboratory

  1. An Integrated Approach to the Undergraduate Biochemistry Laboratory

    Microsoft Academic Search

    James G. Harman; John A. Anderson; Richard A. Nakashima; Robert W. Shaw

    1995-01-01

    Undergraduate biochemistry laboratories traditionally expose students to biochemical techniques through a series of independent and usually unrelated laboratory exercises. Efforts to reorganize and update the undergraduate biochemistry laboratory at Texas Tech University have centered upon the development of a series of laboratory experiments that focus on a single biological system, the complex 11 (succinate:ubiquinone oxidoreductase) of Escherichia coli. Students are

  2. A Curriculum Skills Matrix for Development and Assessment of Undergraduate Biochemistry and Molecular Biology Laboratory Programs

    ERIC Educational Resources Information Center

    Caldwell, Benjamin; Rohlman, Christopher; Benore-Parsons, Marilee

    2004-01-01

    We have designed a skills matrix to be used for developing and assessing undergraduate biochemistry and molecular biology laboratory curricula. We prepared the skills matrix for the Project Kaleidoscope Summer Institute workshop in Snowbird, Utah (July 2001) to help current and developing undergraduate biochemistry and molecular biology program…

  3. An Experiment Using Sucrose Density Gradients in the Undergraduate Biochemistry Laboratory.

    ERIC Educational Resources Information Center

    Turchi, Sandra L.; Weiss, Monica

    1988-01-01

    Describes an experiment to be performed in an undergraduate biochemistry laboratory that is based on a gradient centrifugation system employing a simple bench top centrifuge, a freezer, and frozen surcose gradient solution to separate macromolecules and subcellular components. (CW)

  4. Integrating bio-inorganic and analytical chemistry into an undergraduate biochemistry laboratory.

    PubMed

    Erasmus, Daniel J; Brewer, Sharon E; Cinel, Bruno

    2015-01-01

    Undergraduate laboratories expose students to a wide variety of topics and techniques in a limited amount of time. This can be a challenge and lead to less exposure to concepts and activities in bio-inorganic chemistry and analytical chemistry that are closely-related to biochemistry. To address this, we incorporated a new iron determination by atomic absorption spectroscopy exercise as part of a five-week long laboratory-based project on the purification of myoglobin from beef. Students were required to prepare samples for chemical analysis, operate an atomic absorption spectrophotometer, critically evaluate their iron data, and integrate these data into a study of myoglobin. PMID:25752808

  5. Integrating responsible conduct of research education into undergraduate biochemistry and molecular biology laboratory curricula.

    PubMed

    Hendrickson, Tamara L

    2015-01-01

    Recently, a requirement for directed responsible conduct in research (RCR) education has become a priority in the United States and elsewhere. In the US, both the National Institutes of Health and the National Science Foundation require RCR education for all students who are financially supported by federal awards. The guidelines produced by these agencies offer useful templates for the introduction of RCR materials into courses worldwide. Many academic programs already offer courses or workshops in RCR for their graduate students and for undergraduate science majors and/or researchers. Introducing RCR into undergraduate biochemistry and molecular biology laboratory curricula is another, highly practical way that students can be exposed to these important topics. In fact, a strong argument can be made for integrating RCR into laboratory courses because these classes often introduce students to a scientific environment like that they might encounter in their careers after graduation. This article focuses on general strategies for incorporating explicit RCR education into biochemistry and molecular biology laboratory coursework using the topics suggested by NIH as a starting point. PMID:25727192

  6. HPLC of the Polypeptides in a Hydrolyzate of Egg-White Lysozyme. An Experiment for the Undergraduate Biochemistry Laboratory.

    ERIC Educational Resources Information Center

    Richardson, W. S., III; Burns, L.

    1988-01-01

    Describes a simple high-performance liquid chromatography experiment for undergraduate biochemistry laboratories. The experiment illustrates the separation of polypeptides by a step gradient elution using a single pump instrument with no gradient attachments. Discusses instrumentation, analysis, a sample preparation, and results. (CW)

  7. Glycobiology, How to Sugar-Coat an Undergraduate Advanced Biochemistry Laboratory

    ERIC Educational Resources Information Center

    McReynolds, Katherine D.

    2006-01-01

    A second semester biochemistry laboratory has been implemented as an independent projects course at California State University, Sacramento since 1999. To incorporate aspects of carbohydrate biochemistry, or glycobiology, into our curriculum, projects in lectin isolation and purification were undertaken over the course of two semesters. Through…

  8. Affinity Chromatography of Lactate Dehydrogenase: An Experiment for the Undergraduate Biochemistry Laboratory.

    ERIC Educational Resources Information Center

    Anderson, Alexander J.

    1988-01-01

    Discusses a laboratory technique of enzyme purification by affinity chromatography as part of an undergraduate biochemical methodology course. Provides preparation details of the rat muscle homogenate and reagents. Proposes column requirements and assaying information. (MVL)

  9. A Static Method as an Alternative to Gel Chromatography: An Experiment for the Undergraduate Biochemistry Laboratory

    ERIC Educational Resources Information Center

    Burum, Alex D.; Splittgerber, Allan G.

    2008-01-01

    This article describes a static method as an alternative to gel chromatography, which may be used as an undergraduate laboratory experiment. In this method, a constant mass of Sephadex gel is swollen in a series of protein solutions. UV-vis spectrophotometry is used to find a partition coefficient, KD, that indicates the fraction of the interior…

  10. An Integrated Biochemistry Laboratory, Including Molecular Modeling

    Microsoft Academic Search

    Adele J. Wolfson Mona L. Hall; Thomas R. Branham

    1996-01-01

    The dilemma of designing an advanced undergraduate laboratory lies in the desire to teach and reinforce basic principles and techniques while at the same time exposing students to the excitement of research. We report here on a one-semester, project-based biochemistry laboratory that combines the best features of a cookbook approach (high success rate, achievement of defined goals) with those of

  11. Equilibrium Gel Filtration Chromatography for the Measurement of Protein-Ligand Binding in the Undergraduate Biochemistry Laboratory

    ERIC Educational Resources Information Center

    Craig, Douglas B.

    2005-01-01

    A laboratory exercise used in the senior biochemistry course at the University of Winnipeg for three years is discussed. It combines liquid chromatography and absorbance spectroscopy and also allows the students to produce a quantitative result within a single three-hour period.

  12. Immobilized alpha-Galactosidase in the Biochemistry Laboratory

    ERIC Educational Resources Information Center

    Mulimani, V. H.; Dhananjay, K.

    2007-01-01

    This laboratory experiment was designed to demonstrate the application of immobilized galactosidase in food industry to hydrolyze raffinose family oligosaccharides in soymilk. This laboratory experiment was conducted for postgraduate students of biochemistry and developed for graduate and undergraduate students of biochemistry, biotechnology,…

  13. The Biochemistry of the Muscle Contraction Process: An Undergraduate Laboratory Experiment Using Viscosity to Follow the Progress of a Reaction.

    ERIC Educational Resources Information Center

    Belliveau, James F.; And Others

    1981-01-01

    Describes an undergraduate laboratory experiment using viscosity to follow the progress of the contractile process in muscles. This simple, short experiment illustrates the action of ATP as the source of energy in the contractile process and the catalytic effect of calcium ions as a control in the energy producing process. (CS)

  14. Biochemistry Laboratory II Course Syllabus

    E-print Network

    Houston, Paul L.

    1 Biochemistry Laboratory II CHEM 4582 Course Syllabus #12;2 General Information COURSE OBJECTIVE The primary objective of this course is for students to learn laboratory methods for characterizing biological Laboratory I) TEXT None ­ see T-Square for reading assignments OTHER REQUIREMENTS Laboratory coat **NEW

  15. Doing That Thing That Scientists Do: A Discovery-Driven Module on Protein Purification and Characterization for the Undergraduate Biochemistry Laboratory Classroom

    ERIC Educational Resources Information Center

    Garrett, Teresa A.; Osmundson, Joseph; Isaacson, Marisa; Herrera, Jennifer

    2015-01-01

    In traditional introductory biochemistry laboratory classes students learn techniques for protein purification and analysis by following provided, established, step-by-step procedures. Students are exposed to a variety of biochemical techniques but are often not developing procedures or collecting new, original data. In this laboratory module,…

  16. The Synthesis, Identification, and Kinetic Characterization of the Photoaffinity Label: 3-Azidopyridine Adenosine Dinucleotide: An Advanced Undergraduate Laboratory Experiment Appropriate for Organic, Biochemistry, or Bio-organic Chemistry

    Microsoft Academic Search

    ALLAN A. GAHR; YUZHUO LI

    1997-01-01

    We present here a complete photochemical experiment suitable for biochemistry, bioorganic, and organic chemistry laboratories. It provides experiences in chemical and enzymatic syntheses, spectroscopy (IR, NMR, UV), chromatography (TLC, GC-MS), and a simple enzyme kinetic study utilizing UV spectroscopy. The application of light energy to produce chemical changes has recently expanded beyond photography, lithography, and organic synthesis to include use

  17. Doing that thing that scientists do: A discovery-driven module on protein purification and characterization for the undergraduate biochemistry laboratory classroom.

    PubMed

    Garrett, Teresa A; Osmundson, Joseph; Isaacson, Marisa; Herrera, Jennifer

    2015-05-01

    In traditional introductory biochemistry laboratory classes students learn techniques for protein purification and analysis by following provided, established, step-by-step procedures. Students are exposed to a variety of biochemical techniques but are often not developing procedures or collecting new, original data. In this laboratory module, students develop research skills through work on an original research project and gain confidence in their ability to design and execute an experiment while faculty can enhance their scholarly pursuits through the acquisition of original data in the classroom laboratory. Students are prepared for a 6-8 week discovery-driven project on the purification of the Escherichia coli cytidylate kinase (CMP kinase) through in class problems and other laboratory exercises on bioinformatics and protein structure analysis. After a minimal amount of guidance on how to perform the CMP kinase in vitro enzyme assay, SDS-PAGE, and the basics of protein purification, students, working in groups of three to four, develop a protein purification protocol based on the scientific literature and investigate some aspect of CMP kinase that interests them. Through this process, students learn how to implement a new but perhaps previously worked out procedure to answer their research question. In addition, they learn the importance of keeping a clear and thorough laboratory notebook and how to interpret their data and use that data to inform the next set of experiments. Following this module, students had increased confidence in their ability to do basic biochemistry techniques and reported that the "self-directed" nature of this lab increased their engagement in the project. © 2015 by The International Union of Biochemistry and Molecular Biology, 43(3):145-153, 2015. PMID:25735767

  18. An Integrated Biochemistry Laboratory, Including Molecular Modeling

    NASA Astrophysics Data System (ADS)

    Hall, Adele J. Wolfson Mona L.; Branham, Thomas R.

    1996-11-01

    The dilemma of designing an advanced undergraduate laboratory lies in the desire to teach and reinforce basic principles and techniques while at the same time exposing students to the excitement of research. We report here on a one-semester, project-based biochemistry laboratory that combines the best features of a cookbook approach (high success rate, achievement of defined goals) with those of an investigative, discovery-based approach (student involvement in the experimental design, excitement of real research). Individual modules may be selected and combined to meet the needs of different courses and different institutions. The central theme of this lab is protein purification and design. This laboratory accompanies the first semester of biochemistry (Structure and Function of Macromolecules, a course taken mainly by junior and senior chemistry and biological chemistry majors). The protein chosen as the object of study is the enzyme lysozyme, which is utilized in all projects. It is suitable for a student lab because it is easily and inexpensively obtained from egg white and is extremely stable, and its high isoelectric point (pI = 11) allows for efficient separation from other proteins by ion-exchange chromatography. Furthermore, a literature search conducted by the resourceful student reveals a wealth of information, since lysozyme has been the subject of numerous studies. It was the first enzyme whose structure was determined by crystallography (1). Hendrickson et al. (2) have previously described an intensive one-month laboratory course centered around lysozyme, although their emphasis is on protein stability rather than purification and engineering. Lysozyme continues to be the focus of much exciting new work on protein folding and dynamics, structure and activity (3 - 5). This lab course includes the following features: (i) reinforcement of basic techniques, such as preparation of buffers, simple enzyme kinetics, and absorption spectroscopy; (ii) experience with methods of protein purification; (iii) incorporation of appropriate controls into experiments; (iv) use of basic statistics in data analysis; (v) writing papers and grant proposals in accepted scientific style; (vi) peer review; (vii) oral presentation of results and proposals; and (viii) introduction to molecular modeling. Figure 1 illustrates the modular nature of the lab curriculum. Elements from each of the exercises can be separated and treated as stand-alone exercises, or combined into short or long projects. We have been able to offer the opportunity to use sophisticated molecular modeling in the final module through funding from an NSF-ILI grant. However, many of the benefits of the research proposal can be achieved with other computer programs, or even by literature survey alone. Figure 1.Design of project-based biochemistry laboratory. Modules (projects, or portions of projects) are indicated as boxes. Each of these can be treated independently, or used as part of a larger project. Solid lines indicate some suggested paths from one module to the next. The skills and knowledge required for protein purification and design are developed in three units: (i) an introduction to critical assays needed to monitor degree of purification, including an evaluation of assay parameters; (ii) partial purification by ion-exchange techniques; and (iii) preparation of a grant proposal on protein design by mutagenesis. Brief descriptions of each of these units follow, with experimental details of each project at the end of this paper. Assays for Lysozyme Activity and Protein Concentration (4 weeks) The assays mastered during the first unit are a necessary tool for determining the purity of the enzyme during the second unit on purification by ion exchange. These assays allow an introduction to the concept of specific activity (units of enzyme activity per milligram of total protein) as a measure of purity. In this first sequence, students learn a turbidimetric assay for lysozyme activity and a colorimetric one for protein concentration. Familiarity with the assay

  19. Beyond Google: Integrating Chemical Information into the Undergraduate Chemistry and Biochemistry Curriculum

    Microsoft Academic Search

    Marion C. Peters

    2011-01-01

    At the University of California, Los Angeles, chemical information instruction focuses on partnering with faculty and teaching assistants in integrating the basics into three laboratory courses taken sequentially by chemistry and biochemistry majors. Resources covered include many recommended in “Information Competencies for Chemistry Undergraduates: The Elements of Information Literacy” (http:\\/\\/units.sla.org\\/division\\/dche\\/il\\/cheminfolit.pdf). Instructional activities feature guided exercises in small laboratory sections and

  20. Integrating Internet Assignments into a Biochemistry/Molecular Biology Laboratory Course

    ERIC Educational Resources Information Center

    Kaspar, Roger L.

    2002-01-01

    A main challenge in educating undergraduate students is to introduce them to the Internet and to teach them how to effectively use it in research. To this end, an Internet assignment was developed that introduces students to websites related to biomedical research at the beginning of a biochemistry/molecular biology laboratory course. The basic…

  1. Thermodynamic Exploration of Eosin-Lysozyme Binding: A Physical Chemistry and Biochemistry Laboratory Experiment

    ERIC Educational Resources Information Center

    Huisman, Andrew J.; Hartsell, Lydia R.; Krueger, Brent P.; Pikaart, Michael J.

    2010-01-01

    We developed a modular pair of experiments for use in the undergraduate physical chemistry and biochemistry laboratories. Both experiments examine the thermodynamics of the binding of a small molecule, eosin Y, to the protein lysozyme. The assay for binding is the quenching of lysozyme fluorescence by eosin through resonant energy transfer. In…

  2. A Combustion Laboratory for Undergraduates.

    ERIC Educational Resources Information Center

    Peters, James E.

    1985-01-01

    Describes a combustion laboratory facility and experiments for a senior-level (undergraduate) course in mechanical engineering. The experiment reinforces basic thermodynamic concepts and provides many students with their first opportunity to work with a combustion system. (DH)

  3. 78 FR 4170 - License Amendment Request for Analytical Bio-Chemistry Laboratories, Inc., Columbia, MO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-18

    ...Amendment Request for Analytical Bio-Chemistry Laboratories, Inc., Columbia, MO...24-13365-01 issued to Analytical Bio-Chemistry Laboratories, Inc. (the licensee...accession numbers are: 1. Analytical Bio-Chemistry Laboratories, Inc., Licensee...

  4. Teaching Structure: Student Use of Software Tools for Understanding Macromolecular Structure in an Undergraduate Biochemistry Course

    ERIC Educational Resources Information Center

    Jaswal, Sheila S.; O'Hara, Patricia B.; Williamson, Patrick L.; Springer, Amy L.

    2013-01-01

    Because understanding the structure of biological macromolecules is critical to understanding their function, students of biochemistry should become familiar not only with viewing, but also with generating and manipulating structural representations. We report a strategy from a one-semester undergraduate biochemistry course to integrate use of…

  5. Department of Chemistry & Biochemistry UCLA Chemistry, Biochemistry & Chemistry Material Science

    E-print Network

    Levine, Alex J.

    ..............................................................................................................................................................11 Physical Chemistry ConcentrationDepartment of Chemistry & Biochemistry UCLA Chemistry, Biochemistry & Chemistry Material Science ...........................................................................................................................................4 Chemistry & Biochemistry Undergraduate Office

  6. Utilizing Isolation, Purification, and Characterization of Enzymes as Project-Oriented Labs for Undergraduate Biochemistry

    Microsoft Academic Search

    S. Todd Deal; Michael O. Hurst

    1997-01-01

    Senior-level biochemistry labs are mostly verification-type laboratories with little chance for exploration. We have developed a project-based biochemistry laboratory which gives them a chance to carry out a major biochemistry project. In the first quarter it is based on the purification of the enzyme lysozyme. The students are given some basic information, and then work out the details of their

  7. Undergraduate Laboratory for Surface Science

    NASA Astrophysics Data System (ADS)

    Okumura, Mitchio; Beauchamp, Jesse L.; Dickert, Jeffrey M.; Essy, Blair R.; Claypool, Christopher L.

    1996-02-01

    Surface science has developed into a multidisciplinary field of research with applications ranging from heterogeneous catalysis to semiconductor etching (1). Aspects of surface chemistry are now included in physical chemistry textbooks (2) and undergraduate curricula (3), but the perceived cost and complexity of equipment has deterred the introduction of surface science methods in undergraduate laboratories (4). Efforts to expose chemistry undergraduates to state-of-the-art surface instrumentation have just begun (5). To provide our undergraduates with hands-on experience in using standard techniques for characterizing surface morphology, adsorbates, kinetics, and reaction mechanisms, we have developed a set of surface science experiments for our physical chemistry laboratory sequence. The centerpiece of the laboratory is an ultrahigh vacuum (UHV) chamber for studies of single crystal surfaces. This instrument, shown in the figure, has surface analysis capabilities including low energy electron diffraction (LEED), Auger spectroscopy, and temperature-programmed desorption (TPD). The laboratory exercises involve experiments on the well-studied Pt(111) surface. Students prepare a previously mounted single crystal sample by sputtering it with an argon ion gun and heating it under O2. Electron diffraction patterns from the cleaned surface are then obtained with a reverse view LEED apparatus (Princeton Instruments). Images are captured by a charge-coupled device (CCD) camera interfaced to a personal computer for easy downloading and subsequent analysis. Although the LEED images from a Pt(111) surface can be readily interpreted using simple diffraction arguments, this lab provides an excellent context for introducing Miller indices and reciprocal lattices (6). The surface chemical composition can be investigated by Auger spectroscopy, using the LEED apparatus as a simple energy analyzer. The temperature programmed desorption experiment, which is nearly complete, will be be added to the curriculum this academic year. This experiment introduces students to the concepts of surface adsorption and desorption kinetics. The sample mount can be both heated to 900 oC and cooled by liquid nitrogen, allowing the study of the desorption of a variety of adsorbates, both chemisorbed and physisorbed. Adsorbed species evolving from the heated surface are detected with a quadrupole mass spectrometer. Initially, students will study the desorption kinetics of CO from a Pt(111) surface for a range of coverages and temperature programming rates in order to obtain rate parameters and to test the validity of Redhead's relationship between the activation energy of desorption and the peak desorption temperature. They then will be introduced to the mechanisms of surface reactions (Langmuir-Hinshelwood) in a study of CO oxidation on this surface. We have also set up a scanning tunneling microscopy (STM) laboratory using a commercially available instrument (Burleigh Instruments, Inc.), which complements the UHV surface structure experiments by introducing the topography of a real surface, for example, with steps and defect sites. With the apparatus now completed, we can explore other possible developments, for example, an applied physics track designed around experiments on semiconductor substrates. Future additions include X-ray photoelectron spectroscopy and completion of a separate surface infrared spectroscopy experiment on supported catalysts. We acknowledge support from the National Science Foundation, Division of Undergraduate Education Instrumentation and Laboratory Improvement (ILI) Program (Grant No. DUE-9352254) and an AT&T Special Purpose Grant. Literature Cited Somorjai, G. Introduction to Surface Chemistry and Catalysis; Wiley: New York, 1994; Woodruff, D. P.; Delchar, T. A. Modem Techniques of Surface Science; Cambridge University: Cambridge, 1986; Christmann, K. Introduction to Surface Physical Chemistry; Springer Verlag: New York, 1991; Adamson, A. W. Physical Chemistry of Surfaces, 5th ed.; Wiley: New York, 1990. See for example Atki

  8. Fighting Tuberculosis in an Undergraduate Laboratory: Synthesizing, Evaluating and Analyzing Inhibitors

    ERIC Educational Resources Information Center

    Daniels, David; Berkes, Charlotte; Nekoie, Arjan; Franco, Jimmy

    2015-01-01

    A drug discovery project has been successfully implemented in a first-year general, organic, and biochemistry (GOB) health science course and second-year organic undergraduate chemistry course. This project allows students to apply the fundamental principles of chemistry and biology to a problem of medical significance, practice basic laboratory

  9. Department of Laboratory Medicine & Pathology Division of Medical Biochemistry

    E-print Network

    MacMillan, Andrew

    and Canadian Society of Clinical Chemistry funds. Graduates of this fellowship program meet curriculum responsibility to lead clinical chemistry laboratories in hospitals affiliated with academic centers, in small requirements for both the Canadian Academy of Clinical Biochemistry and the American Board of Clinical

  10. Industrial Approach to Undergraduate Polymer Laboratory.

    ERIC Educational Resources Information Center

    Staskiewicz, Bernard A.; And Others

    1984-01-01

    Describes an undergraduate polymer laboratory program in which the laboratory simulates an industrial organization. The goals of the program are to foster an understanding of the properties of polymers and how they change, their preparation, and industrial application. (JN)

  11. A Proposal for Teaching Undergraduate Chemistry Students Carbohydrate Biochemistry by Problem-Based Learning Activities

    ERIC Educational Resources Information Center

    Figueira, Angela C. M.; Rocha, Joao B. T.

    2014-01-01

    This article presents a problem-based learning (PBL) approach to teaching elementary biochemistry to undergraduate students. The activity was based on "the foods we eat." It was used to engage students' curiosity and to initiate learning about a subject that could be used by the future teachers in the high school. The experimental…

  12. A Course Designed for Undergraduate Biochemistry Students to Learn about Cultural Diversity Issues

    ERIC Educational Resources Information Center

    Benore-Parsons, Marilee

    2006-01-01

    Biology, biochemistry, and other science students are well trained in science and familiar with how to conduct and evaluate scientific experiments. They are less aware of cultural issues or how these will impact their careers in research, education, or as professional health care workers. A course was developed for advanced undergraduate science…

  13. The Views of Undergraduates about Problem-Based Learning Applications in a Biochemistry Course

    ERIC Educational Resources Information Center

    Tarhan, Leman; Ayyildiz, Yildizay

    2015-01-01

    The effect of problem-based learning (PBL) applications in an undergraduate biochemistry course on students' interest in this course was investigated through four modules during one semester. Students' views about active learning and improvement in social skills were also collected and evaluated. We conducted the study with 36 senior students from…

  14. Myoglobin structure and function: A multiweek biochemistry laboratory project.

    PubMed

    Silverstein, Todd P; Kirk, Sarah R; Meyer, Scott C; Holman, Karen L McFarlane

    2015-05-01

    We have developed a multiweek laboratory project in which students isolate myoglobin and characterize its structure, function, and redox state. The important laboratory techniques covered in this project include size-exclusion chromatography, electrophoresis, spectrophotometric titration, and FTIR spectroscopy. Regarding protein structure, students work with computer modeling and visualization of myoglobin and its homologues, after which they spectroscopically characterize its thermal denaturation. Students also study protein function (ligand binding equilibrium) and are instructed on topics in data analysis (calibration curves, nonlinear vs. linear regression). This upper division biochemistry laboratory project is a challenging and rewarding one that not only exposes students to a wide variety of important biochemical laboratory techniques but also ties those techniques together to work with a single readily available and easily characterized protein, myoglobin. © 2015 by The International Union of Biochemistry and Molecular Biology, 43(3):181-188, 2015. PMID:25726810

  15. Argumentation in undergraduate chemistry laboratories

    NASA Astrophysics Data System (ADS)

    Walker, Joi Phelps

    To address the need for reform in undergraduate science education a new instructional model called Argument-Driven Inquiry (ADI) was developed and then implemented in a undergraduate chemistry course at a community college in the southeastern United States (Sampson, Walker, & Grooms, 2009; Walker, Sampson, & Zimmerman, in press). The ADI instructional model is designed to give a more central place to argumentation and the role of argument in the social construction of scientific knowledge. This research investigated the growth in the quality of the student generated arguments and the scientific argumentation that took place over the course of a semester. Students enrolled in two sections of General Chemistry I laboratory at the community college participated in this study. The students worked in collaborative groups of three or four. The students were given a variation of the same performance task three times during the semester in order to measure individual ability to use evidence and justify their choice of evidence with appropriate rationale. Five ADI investigations took place during the semester and the laboratory reports for each were collected from each student and the argument section of each report was scored. All the student groups were video recorded five times during the semester as they generated and evaluated arguments and the quality of the group argumentation was assessed using an instrument called the Assessment of Scientific Argumentation in the Classroom (ASAC) observation protocol. As time was the independent variable in this study a repeated measure ANOVA was used to evaluate the significance of student improvement in each area (argumentation, written argument and performance task) over the course of the semester (Trochim, 1999). In addition, a multiple regression analysis was conducted to evaluate how well the ASAC scores predicted individual scores on both the performance task and the written arguments (Green & Salkind, 2005). There was significant growth over the course of the semester in all three measures, performance-based assessment, written argument and oral argumentation. There also was a significant correlation between written and oral arguments that was used to generate a linear model using oral argumentation as a predictor of written argument. The results of this suggest that the use of an integrated instructional model such as ADI can have a positive impact on the quality of the arguments students include in their investigation reports, the argumentation they engage in during lab activities, and their overall performance on tasks that require them to develop and support a valid conclusion with genuine evidence.

  16. Cytochrome C: A Biochemistry Laboratory Course

    ERIC Educational Resources Information Center

    Vincent, John B.; Woski, Stephen A.

    2005-01-01

    A laboratory course called cytochrome c that focuses on the theme of biochemical research is presented. The students follow this course by incorporating team-investigation and self-directed experimentation that provides them an opportunity to experience the excitement of research.

  17. Argumentation in Undergraduate Chemistry Laboratories

    ERIC Educational Resources Information Center

    Walker, Joi Phelps

    2011-01-01

    To address the need for reform in undergraduate science education a new instructional model called "Argument-Driven Inquiry" (ADI) was developed and then implemented in a undergraduate chemistry course at a community college in the southeastern United States (Sampson, Walker, & Grooms, 2009; Walker, Sampson, & Zimmerman, in press). The ADI…

  18. Kinetics of Papain: An Introductory Biochemistry Laboratory Experiment

    Microsoft Academic Search

    Kathleen Cornely; Eric Crespo; Michael Earley; Rachel Kloter; Aime Levesque; Mary Pickering

    1999-01-01

    Enzyme kinetics experiments are popular in the undergraduate laboratory. These experiments have pedagogic value because they reinforce the concepts of Michaelis-Menten kinetics covered in the lecture portion of the course and give students the experience of calculating kinetic constants from data they themselves have generated. In this experiment, we investigate the kinetics of the thiol protease papain. The source of

  19. A Fast and Inexpensive Western Blot Experiment for the Undergraduate Laboratory

    NASA Astrophysics Data System (ADS)

    Farrell, Shawn O.; Farrell, Lynn E.

    1995-08-01

    Western blotting is an important, modern technique for transferring proteins from a gel onto nitrocellulose or other suitable support and then detecting a protein of interest using antibodies. We have developed an experiment and optimized the conditions for the undergraduate laboratory. The experiment can be done quickly using an electrophoretic blotter or more cheaply using passive transfer. This experiment allows the student to learn valuable procedures currently used in biochemistry and other biological sciences.

  20. Guaiacol Peroxidase Zymography for the Undergraduate Laboratory

    ERIC Educational Resources Information Center

    Wilkesman, Jeff; Castro, Diana; Contreras, Lellys M.; Kurz, Liliana

    2014-01-01

    This laboratory exercise presents a novel way to introduce undergraduate students to the specific detection of enzymatic activity by electrophoresis. First, students prepare a crude peroxidase extract and then analyze the homogenate via electrophoresis. Zymography, that is, a SDS-PAGE method to detect enzyme activity, is used to specifically…

  1. Undergraduate Organic Chemistry Laboratory Safety

    NASA Astrophysics Data System (ADS)

    Luckenbaugh, Raymond W.

    1996-11-01

    Each organic chemistry student should become familiar with the educational and governmental laboratory safety requirements. One method for teaching laboratory safety is to assign each student to locate safety resources for a specific class laboratory experiment. The student should obtain toxicity and hazardous information for all chemicals used or produced during the assigned experiment. For example, what is the LD50 or LC50 for each chemical? Are there any specific hazards for these chemicals, carcinogen, mutagen, teratogen, neurotixin, chronic toxin, corrosive, flammable, or explosive agent? The school's "Chemical Hygiene Plan", "Prudent Practices for Handling Hazardous Chemicals in the Laboratory" (National Academy Press), and "Laboratory Standards, Part 1910 - Occupational Safety and Health Standards" (Fed. Register 1/31/90, 55, 3227-3335) should be reviewed for laboratory safety requirements for the assigned experiment. For example, what are the procedures for safe handling of vacuum systems, if a vacuum distillation is used in the assigned experiment? The literature survey must be submitted to the laboratory instructor one week prior to the laboratory session for review and approval. The student should then give a short presentation to the class on the chemicals' toxicity and hazards and describe the safety precautions that must be followed. This procedure gives the student first-hand knowledge on how to find and evaluate information to meet laboartory safety requirements.

  2. Preparing the Biochemistry Laboratory for the Next Outbreak: Lessons from SARS in Singapore

    PubMed Central

    2005-01-01

    Severe acute respiratory syndrome (SARS) is an emerging disease characterised by fever and atypical pneumonia and caused by a novel coronavirus. Singapore was affected by the global pandemic in early 2003, with 238 cases and 33 deaths. Samples sent to the biochemistry laboratory made up the majority (69%) of all SARS samples, yet remained a minority (29%) of total biochemistry workload. This paper describes the problems encountered and solutions adopted by the biochemistry laboratory at the designated SARS hospital in coping with this epidemic. It provides practical advice for laboratories planning for the handling of samples from future outbreaks. PMID:16450013

  3. Structure Leads To Function: An Integrated Biophysical Approach To Teaching a Biochemistry Laboratory.

    ERIC Educational Resources Information Center

    And Others; deLannoy, Peter

    1996-01-01

    Describes an integrated approach to teaching a biochemistry laboratory focusing on the relationship between the three-dimensional structure of a macromolecule and its function. RNA is chosen as the model system. Discusses curriculum and student assessment. (AIM)

  4. A Multistep Synthesis for an Advanced Undergraduate Organic Chemistry Laboratory

    ERIC Educational Resources Information Center

    Chang Ji; Peters, Dennis G.

    2006-01-01

    Multistep syntheses are often important components of the undergraduate organic laboratory experience and a three-step synthesis of 5-(2-sulfhydrylethyl) salicylaldehyde was described. The experiment is useful as a special project for an advanced undergraduate organic chemistry laboratory course and offers opportunities for students to master a…

  5. Kinetics of Papain: An Introductory Biochemistry Laboratory Experiment

    NASA Astrophysics Data System (ADS)

    Cornely, Kathleen; Crespo, Eric; Earley, Michael; Kloter, Rachel; Levesque, Aime; Pickering, Mary

    1999-05-01

    Enzyme kinetics experiments are popular in the undergraduate laboratory. These experiments have pedagogic value because they reinforce the concepts of Michaelis-Menten kinetics covered in the lecture portion of the course and give students the experience of calculating kinetic constants from data they themselves have generated. In this experiment, we investigate the kinetics of the thiol protease papain. The source of the papain is commercially available papaya latex. A specific substrate, Na-benzoyl-arginine-p-nitroanilide (BAPNA), is used, which takes advantage of the fact that papain interacts with a phenylalanine residue two amino acids away from the peptide bond cleaved. Upon hydrolysis by papain, a bright yellow product is released, p-nitroaniline. This allows the reaction to be monitored spectrophotometrically by measuring the rate of formation of the p-nitroaniline product as a function of the increase in absorbance of the solution at the lmax of p-nitroaniline (400 nm) over time at various substrate concentrations. These data are used to plot a Lineweaver-Burk plot from which the vmax and KM are obtained. If time permits, students carry out additional investigations in which e of p-nitroaniline is measured, the enzyme solution protein concentration is measured, the enzyme purity is evaluated by SDS-PAGE, and a pH-rate profile is constructed from experimental data.

  6. Undergraduate research and new laboratory practices in power engineering

    Microsoft Academic Search

    Efraín O'Neill-Carrillo; Tania Martínez-Navedo; José Ramos; Miguel Vélez-Reyes; Eddie Marrero

    2002-01-01

    A recent NSF Course, Curriculum and Laboratory Improvement (CCLI) grant supported the adaptation and creation of activities that connect power engineering theory to actual scaled-implementations at the University of Puerto Rico-Mayaguez (UPRM). To this end, laboratory practices and undergraduate research projects were conducted at the new Energy Systems Instrumentation Laboratory (ESIL). Activities at ESIL include: traditional laboratory practices; laboratory practices

  7. Innovative research and laboratory experiences for undergraduate students

    Microsoft Academic Search

    Kathleen L. Kitto

    1998-01-01

    Students majoring in Engineering Technology programs at Western Washington University (USA) have many opportunities to participate in unique undergraduate research experiences and innovative laboratory programs. This paper describes the methods used by the faculty to integrate innovative design experiences into the undergraduate programs at Western Washington University. The CIM projects in the Manufacturing Engineering Technology program are used to illustrate

  8. Commentary: Why Abandoning Undergraduate Laboratories Is Not an Option

    ERIC Educational Resources Information Center

    Costa, Manuel Joao

    2010-01-01

    Laboratory exercises (labs) are sometimes regarded as dispensable in biochemistry and molecular biology (BMB) education for various reasons including a combination of increased class costs and small budget allocations, pressing demands for more time to lecture to fit in new BMB discoveries within constant time span of courses, and the fact that…

  9. 479Program of Medical Laboratory Sciences Undergraduate Catalogue 201314

    E-print Network

    Shihadeh, Alan

    , antigens, antibodies, and complement system, as well as basic principles in blood banking and transfusion medicine. First semester. #12;480 Program of Medical Laboratory Sciences Undergraduate Catalogue 2013

  10. Measuring Dynamic Kidney Function in an Undergraduate Physiology Laboratory

    ERIC Educational Resources Information Center

    Medler, Scott; Harrington, Frederick

    2013-01-01

    Most undergraduate physiology laboratories are very limited in how they treat renal physiology. It is common to find teaching laboratories equipped with the capability for high-resolution digital recordings of physiological functions (muscle twitches, ECG, action potentials, respiratory responses, etc.), but most urinary laboratories still rely on…

  11. Undergraduate Skills Laboratories at Sonoma State University

    NASA Astrophysics Data System (ADS)

    Gill, Amandeep; Zack, K.; Mills, H.; Cunningham, B.; Jackowski, S.

    2014-01-01

    Due to the current economic climate, funding sources for many laboratory courses have been cut from university budgets. However, it is still necessary for undergraduates to master laboratory skills to be prepared and competitive applicants when entering the professional world and/or graduate school. In this context, student-led programs may be able to compensate for this lack of formal instruction and reinforce concepts from lecture by applying research techniques to develop hands-on comprehension. The Sonoma State University Chapter of Society of Physics Students has established a peer-led skills lab to teach research techniques in the fields of astronomy and physics. The goal is to alleviate the pressures of both independently learning and efficiently applying techniques to junior and senior-level research projects. These skill labs are especially valuable for nontraditional students who, due to work or family duties, may not get a chance to fully commit to research projects. For example, a topic such as Arduino programming has a multitude of applications in both astronomy and physics, but is not taught in traditional university courses. Although some programming and electronics skills are taught in (separate) classes, they are usually not applied to actual research projects, which combined expertise is needed. For example, in astronomy, there are many situations involving programming telescopes and taking data with electronic cameras. Often students will carry out research using these tools but when something goes wrong, the students will not have the skills to trouble shoot and fix the system. Another astronomical topic to be taught in the skills labs is the analysis of astronomical data, including running remote telescopes, analyzing photometric variability, and understanding the concepts of star magnitudes, flat fields, and biases. These workshops provide a setting in which the student teacher may strengthen his or her understanding of the topic by presenting it to peers. Students teaching fellow peers is an ideal method of furthering understanding for all participants, and the skills lab established by the SPS has begun this process at SSU.

  12. Introducing Undergraduates to a Research Laboratory

    ERIC Educational Resources Information Center

    Weinberg, Robert

    1974-01-01

    Discusses a student project which is intended to teach undergraduates concepts and techniques of nuclear physics, experimental methods used in particle detection, and provide experience in a functioning research environment. Included are detailed procedures for carrying out the project. (CC)

  13. Working with Enzymes - Where Is Lactose Digested? An Enzyme Assay for Nutritional Biochemistry Laboratories

    NASA Astrophysics Data System (ADS)

    Pope, Sandi R.; Tolleson, Tonya D.; Williams, R. Jill; Underhill, Russell D.; Deal, S. Todd

    1998-06-01

    At Georgia Southern University, we offer a sophomore-level introductory biochemistry course that is aimed at nutrition and chemistry education majors. The laboratory portion of this course has long lacked an experimental introduction to enzymes. We have developed a simple enzyme assay utilizing lactase enzyme from crushed LactAid tablets and a 5% lactose solution ("synthetic milk"). In the experiment, the students assay the activity of the enzyme on the "synthetic milk" at pHs of approximately 1, 6, and 8 with the stated goal of determining where lactose functions in the digestive tract. The activity of the lactase may be followed chromatographically or spectrophotometrically. The experiment, which is actually a simple pH assay, is easily implemented in allied health chemistry laboratory courses and readily lends itself to adaptation for more complex kinetic assays in upper-level biochemistry laboratory courses. The experimental details, including a list of required supplies and hints for implementation, are provided.

  14. COURSE NAME TERM CR COURSE NAME TERM CR BC 401 Comprehensive Biochemistry I F 3 CHEM 334 Quantitative Analysis Laboratory F, S 1

    E-print Network

    Stephens, Graeme L.

    Quantitative Analysis Laboratory F, S 1 BC 403 Comprehensive Biochemistry II S 3 CHEM 335 Intro to Analytical Chemistry F,S 3 BC 404 Comprehensive Biochemistry Laboratory F,S 2 CHEM 343 Modern Organic Chemistry II F,S,SS 3 BC 411 Physical Biochemistry F 4 CHEM 433& Clinical Chemistry S 3 BC 463 Molecular Genetics F 3

  15. The IWAR range: a laboratory for undergraduate information assurance education

    Microsoft Academic Search

    Joseph Schafer; Daniel J. Ragsdale; John R. Surdu; Curtis A. Carver

    2001-01-01

    This paper describes a unique resource at West Point, the Information Analysis and Research Laboratory, referred to as the IWAR range. The IWAR range is an isolated laboratory used by undergraduate students and faculty researchers. The IWAR is a production-system-like, heterogeneous environment. The IWAR has become a vital part of the Information Assurance curriculum at West Point. We use the

  16. Can Computer Simulations Replace Real Equipment in Undergraduate Laboratories?

    E-print Network

    Colorado at Boulder, University of

    Can Computer Simulations Replace Real Equipment in Undergraduate Laboratories? N. D. Finkelstein, K, Boulder Abstract. This paper examines the effects of substituting computer simulations in place of real (DC) circuit laboratory was modified to compare the effects of using computer simulations

  17. An Undergraduate Nanotechnology Engineering Laboratory Course on Atomic Force Microscopy

    ERIC Educational Resources Information Center

    Russo, D.; Fagan, R. D.; Hesjedal, T.

    2011-01-01

    The University of Waterloo, Waterloo, ON, Canada, is home to North America's first undergraduate program in nanotechnology. As part of the Nanotechnology Engineering degree program, a scanning probe microscopy (SPM)-based laboratory has been developed for students in their fourth year. The one-term laboratory course "Nanoprobing and Lithography"…

  18. Myoglobin Structure and Function: A Multiweek Biochemistry Laboratory Project

    ERIC Educational Resources Information Center

    Silverstein, Todd P.; Kirk, Sarah R.; Meyer, Scott C.; Holman, Karen L. McFarlane

    2015-01-01

    We have developed a multiweek laboratory project in which students isolate myoglobin and characterize its structure, function, and redox state. The important laboratory techniques covered in this project include size-exclusion chromatography, electrophoresis, spectrophotometric titration, and FTIR spectroscopy. Regarding protein structure,…

  19. EDITORIAL: Student undergraduate laboratory and project work

    NASA Astrophysics Data System (ADS)

    Schumacher, Dieter

    2007-05-01

    During the last decade 'labwork' courses at university level have changed significantly. The beginning of this development was indicated and partly initiated by the EU-project 'Labwork in Science Education' funded by the European Community (1999-2001). The present special issue of the European Journal of Physics focuses on a multitude of different aspects of this process. The aim of this publication is to improve the exchange of experience and to promote this important trend. In physics research labs a silent revolution has taken place. Today the personal computer is omnipresent. It controls the experiment via stepping motors, piezo-microdrives etc, it monitors all parameters and collects the experimental data with the help of smart sensors. In particular, computer-based modern scanning and imaging techniques open the possibility of creating really new types of experiments. The computer allows data storage and processing on the one hand and simulation and modelling on the other. These processes occur in parallel or may even be interwoven. The web plays an important role in modern science for inquiry, communication, cooperation and publication. Traditional labwork courses do not prepare students for the many resulting demands. Therefore it is necessary to redefine the learning targets and to reconsider the learning methods. Two contributions show exemplarily how modern experimental devices could find their way into students' labs. In the article 'Infrared thermal imaging as a tool in university physics education' by Klaus-Peter Möllmann and Michael Vollmer we can see that infrared thermal imaging is a valuable tool in physics education at university level. It can help to visualize and thereby enhance understanding of physical phenomena of mechanics, thermal physics, electromagnetism, optics and radiation physics. The contribution 'Using Peltier cells to study solid-liquid-vapor transitions and supercooling' by Giacomo Torzo, Isabella Soletta and Mario Branca proves that new experiments which illustrate both fundamental physics and modern technology can be realized even with a small budget. Traditional labwork courses often provide a catalogue of well known experiments. The students must first learn the theoretical background. They then assemble the setup from specified equipment, collect the data and perform the default data processing. However, there is no way to learn to swim without water. In order to achieve a constructivist access to learning, 'project labs' are needed. In a project labwork course a small group of students works as a team on a mini research project. The students have to specify the question of research, develop a suitable experimental setup, conduct the experiment and find a suitable way to evaluate the data. Finally they must present their results e.g. in the framework of a public poster session. Three contributions refer to this approach, however they focus on different aspects: 'Project laboratory for first-year students' by Gorazd Planinši?, 'RealTime Physics: active learning laboratories' by David Sokoloff et al and 'Labs outside labs: miniprojects at a spring camp for future physics teachers' by Leos Dvorák. Is it possible to prepare the students specifically for project labwork? This question is answered by the contribution 'A new labwork course for physics students: devices, methods and research projects' by Knut Neumann and Manuela Welzel. The two main parts of the labwork course cover first experimental devices (e.g. multimeters, oscilloscopes, different sensors, operational amplifiers, step motors, AD/DA-converters). Then subjects such as data processing, consideration of measurement uncertainties, keeping records or using tools like LABVIEW etc are focused on. Another concrete proposal for a new curriculum is provided by James Sharp et al, in 'Computer based learning in an undergraduate physics laboratory: interfacing and instrument control using MATLAB'. One can well imagine that project labs will be the typical learning environment for physics students in the future. However, the de

  20. National Science Foundation Research Experiences for Undergraduates

    E-print Network

    -baccalaureate undergraduate students majoring in biochemistry, chemistry, genetics, biology, or any life science. Preference students to participate in a 10-week intensive summer research program during the summer of 2013. Under the direction of our faculty, students will join a laboratory team to conduct research in modern biochemistry

  1. Rapid and Adaptable Measurement of Protein Thermal Stability by Differential Scanning Fluorimetry: Updating a Common Biochemical Laboratory Experiment

    ERIC Educational Resources Information Center

    Johnson, R. Jeremy; Savas, Christopher J.; Kartje, Zachary; Hoops, Geoffrey C.

    2014-01-01

    Measurement of protein denaturation and protein folding is a common laboratory technique used in undergraduate biochemistry laboratories. Differential scanning fluorimetry (DSF) provides a rapid, sensitive, and general method for measuring protein thermal stability in an undergraduate biochemistry laboratory. In this method, the thermal…

  2. Fluorescence quantum yield measurements of fluorescent proteins: a laboratory experiment for a biochemistry or molecular biophysics laboratory course.

    PubMed

    Wall, Kathryn P; Dillon, Rebecca; Knowles, Michelle K

    2015-01-01

    Fluorescent proteins are commonly used in cell biology to assess where proteins are within a cell as a function of time and provide insight into intracellular protein function. However, the usefulness of a fluorescent protein depends directly on the quantum yield. The quantum yield relates the efficiency at which a fluorescent molecule converts absorbed photons into emitted photons and it is necessary to know for assessing what fluorescent protein is the most appropriate for a particular application. In this work, we have designed an upper-level, biochemistry laboratory experiment where students measure the fluorescence quantum yields of fluorescent proteins relative to a standard organic dye. Four fluorescent protein variants, enhanced cyan fluorescent protein (ECFP), enhanced green fluorescent protein (EGFP), mCitrine, and mCherry, were used, however the methods described are useful for the characterization of any fluorescent protein or could be expanded to fluorescent quantum yield measurements of organic dye molecules. The laboratory is designed as a guided inquiry project and takes two, 4 hr laboratory periods. During the first day students design the experiment by selecting the excitation wavelength, choosing the standard, and determining the concentration needed for the quantum yield experiment that takes place in the second laboratory period. Overall, this laboratory provides students with a guided inquiry learning experience and introduces concepts of fluorescence biophysics into a biochemistry laboratory curriculum. PMID:25395254

  3. A Laboratory Based Capstone Course in Computer Security for Undergraduates

    E-print Network

    O'Leary, Michael

    & Information Science Education]: Computer Science education, Curriculum General Terms Security, ExperimentationA Laboratory Based Capstone Course in Computer Security for Undergraduates Mike O'Leary Department of Computer and Information Science Towson University Towson, MD 21252 +1 410-704-4757 moleary

  4. The Wittig Reaction in the Undergraduate Organic Laboratory.

    ERIC Educational Resources Information Center

    Warner, John C.; And Others

    1985-01-01

    Although it is a major synthetic reaction, the Wittig reaction has not been used in undergraduate laboratories due to the potential hazard and difficulty associated with the preparation/use of the strong bases needed to generate the required ylides. Procedures are presented for an experiment in which these difficulties are avoided. (JN)

  5. Synthesis and Characterization of Silver Nanoparticles for an Undergraduate Laboratory

    ERIC Educational Resources Information Center

    Orbaek, Alvin W.; McHale, Mary M.; Barron, Andrew R.

    2015-01-01

    The aim of this simple, quick, and safe laboratory exercise is to provide undergraduate students an introduction to nanotechnology using nanoparticle (NP) synthesis. Students are provided two procedures that allow for the synthesis of different yet controlled sizes of silver NPs. After preparing the NPs, the students perform UV-visible…

  6. Micro-Raman spectroscopy in the undergraduate research laboratory

    Microsoft Academic Search

    R. Voor; L. Chow; A. Schulte

    1994-01-01

    Modern materials science requires processing and characterization techniques for microscopic structures. Molecular probes such as Raman spectroscopy are some of the most viable tools, particularly if they are supplemented by imaging to obtain spatially resolved compositional information of inhomogeneous or low volume samples. In order to introduce these techniques and materials science experiments into the advanced undergraduate laboratory, we have

  7. Analysis of a p53 Mutation Associated with Cancer Susceptibility for Biochemistry and Genetic Laboratory Courses

    ERIC Educational Resources Information Center

    Soto-Cruz, Isabel; Legorreta-Herrera, Martha

    2009-01-01

    We have devised and implemented a module for an upper division undergraduate laboratory based on the amplification and analysis of a p53 polymorphism associated with cancer susceptibility. First, students collected a drop of peripheral blood cells using a sterile sting and then used FTA cards to extract the genomic DNA. The p53 region is then PCR…

  8. Making Connections in the Undergraduate Laboratory.

    ERIC Educational Resources Information Center

    Poole, Bobbie J.; Kidder, Stanley Q.

    1996-01-01

    Describes a strategy used in a meteorology course to increase its relevance to students' lives. Involves combining the lecture and laboratory portions of the course and including a Connections section in the lab report in which students comment on the connections they saw between the coursework, the laboratory exercises, and their own experience.…

  9. Undergraduate Laboratory Module on Skin Diffusion

    ERIC Educational Resources Information Center

    Norman, James J.; Andrews, Samantha N.; Prausnitz, Mark R.

    2011-01-01

    To introduce students to an application of chemical engineering directly related to human health, we developed an experiment for the unit operations laboratory at Georgia Tech examining diffusion across cadaver skin in the context of transdermal drug delivery. In this laboratory module, students prepare mouse skin samples, set up diffusion cells…

  10. Basic neuron model electrical equivalent circuit: an undergraduate laboratory exercise.

    PubMed

    Dabrowski, Katie M; Castaño, Diego J; Tartar, Jaime L

    2013-01-01

    We developed a hands-on laboratory exercise for undergraduate students in which they can build and manipulate a neuron equivalent circuit. This exercise uses electrical circuit components that resemble neuron components and are easy to construct. We describe the methods for creating the equivalent circuit and how to observe different neuron properties through altering the structure of the equivalent circuit. We explain how this hands-on laboratory activity allows for the better understanding of this fundamental neuroscience concept. At the conclusion of this laboratory exercise, undergraduate students will be able to apply the principles of Ohm's law, cable theory with regards to neurons, and understand the functions of resistance and capacitance in a neuron. PMID:24319391

  11. Case-Study Investigation of Equine Maternity via PCR-RFLP: A Biochemistry Laboratory Experiment

    PubMed Central

    Millard, Julie T.; Chuang, Edward; Lucas, James S.; Nagy, Erzsebet E.; Davis, Griffin T.

    2013-01-01

    A simple and robust biochemistry laboratory experiment is described that uses restriction fragment length polymorphism (RFLP) of polymerase chain reaction (PCR) products to verify the identity of a potentially valuable horse. During the first laboratory period, students purify DNA from equine samples and amplify two loci of mitochondrial DNA. During the second laboratory period, students digest PCR products with restriction enzymes and analyze the fragment sizes through agarose gel electrophoresis. An optional step of validating DNA extracts through realtime PCR can expand the experiment to three weeks. This experiment, which has an engaging and versatile scenario, provides students with exposure to key principles and techniques of molecular biology, bioinformatics, and evolution in a forensic context. PMID:24363455

  12. Microcomputers in an Undergraduate Optics Laboratory.

    ERIC Educational Resources Information Center

    Tomaselli, V. P.; And Others

    1990-01-01

    Describes a junior-level, one-year optics laboratory course for physics and engineering students. The course offers a range of experiments from conventional geometric optics to contemporary spatial filtering and fiber optics. Presents an example of an experiment with pictures. (Author/YP)

  13. A Virtual Embedded Microcontroller Laboratory for Undergraduate Education: Development and Evaluation

    ERIC Educational Resources Information Center

    Richardson, Jeffrey J.; Adamo-Villani, Nicoletta

    2010-01-01

    Laboratory instruction is a major component of the engineering and technology undergraduate curricula. Traditional laboratory instruction is hampered by several factors including limited access to resources by students and high laboratory maintenance cost. A photorealistic 3D computer-simulated laboratory for undergraduate instruction in…

  14. An undergraduate laboratory activity demonstrating bacteriophage specificity.

    PubMed

    Allen, Mary E; Gyure, Ruth A

    2013-01-01

    Bacteriophage are among the most diverse and numerous microbes inhabiting our planet. Yet many laboratory activities fail to engage students in meaningful exploration of their diversity, unique characteristics, and abundance. In this curriculum activity students use a standard plaque assay to enumerate bacteriophage particles from a natural sample and use the scientific method to address questions about host specificity and diversity. A raw primary sewage sample is enriched for bacteriophage using hosts in the family Enterobacteriaceae. Students hypothesize about host specificity and use quantitative data (serial dilution and plaque assay) to test their hypotheses. Combined class data also help them answer questions about phage diversity. The exercise was field tested with a class of 47 students using pre- and posttests. For all learning outcomes posttest scores were higher than pretest scores at or below p = 0.01. Average individualized learning gain (G) was also calculated for each learning outcome. Students' use of scientific language in reference to bacteriophage and host interaction significantly improved (p = 0.002; G = 0.50). Improved means of expression helped students construct better hypotheses on phage host specificity (G = 0.31, p = 0.01) and to explain the plaque assay method (G = 0.33, p = 0.002). At the end of the exercise students also demonstrated improved knowledge and understanding of phage specificity as related to phage therapy in humans (p < 0.001; G = 51). PMID:23858357

  15. Experiences of mentors training underrepresented undergraduates in the research laboratory.

    PubMed

    Prunuske, Amy J; Wilson, Janelle; Walls, Melissa; Clarke, Benjamin

    2013-01-01

    Successfully recruiting students from underrepresented groups to pursue biomedical science research careers continues to be a challenge. Early exposure to scientific research is often cited as a powerful means to attract research scholars with the research mentor being critical in facilitating the development of an individual's science identity and career; however, most mentors in the biological sciences have had little formal training in working with research mentees. To better understand mentors' experiences working with undergraduates in the laboratory, we conducted semistructured interviews with 15 research mentors at a public university in the Midwest. The interviewed mentors were part of a program designed to increase the number of American Indians pursuing biomedical/biobehavioral research careers and represented a broad array of perspectives, including equal representation of male and female mentors, mentors from underrepresented groups, mentors at different levels of their careers, and mentors from undergraduate and professional school departments. The mentors identified benefits and challenges in being an effective mentor. We also explored what the term underrepresented means to the mentors and discovered that most of the mentors had an incomplete understanding about how differences in culture could contribute to underrepresented students' experience in the laboratory. Our interviews identify issues relevant to designing programs and courses focused on undergraduate student research. PMID:24006389

  16. Experiences of Mentors Training Underrepresented Undergraduates in the Research Laboratory

    PubMed Central

    Prunuske, Amy J.; Wilson, Janelle; Walls, Melissa; Clarke, Benjamin

    2013-01-01

    Successfully recruiting students from underrepresented groups to pursue biomedical science research careers continues to be a challenge. Early exposure to scientific research is often cited as a powerful means to attract research scholars with the research mentor being critical in facilitating the development of an individual's science identity and career; however, most mentors in the biological sciences have had little formal training in working with research mentees. To better understand mentors’ experiences working with undergraduates in the laboratory, we conducted semistructured interviews with 15 research mentors at a public university in the Midwest. The interviewed mentors were part of a program designed to increase the number of American Indians pursuing biomedical/biobehavioral research careers and represented a broad array of perspectives, including equal representation of male and female mentors, mentors from underrepresented groups, mentors at different levels of their careers, and mentors from undergraduate and professional school departments. The mentors identified benefits and challenges in being an effective mentor. We also explored what the term underrepresented means to the mentors and discovered that most of the mentors had an incomplete understanding about how differences in culture could contribute to underrepresented students’ experience in the laboratory. Our interviews identify issues relevant to designing programs and courses focused on undergraduate student research. PMID:24006389

  17. Oxygen Uptake by a Cobalt(II) Complex: An Undergraduate Experiment

    ERIC Educational Resources Information Center

    Appleton, Trevor G.

    1977-01-01

    An experimental procedure is described for studying oxygen uptake by a transition metal. This procedure is designed for use with undergraduates and may be used in organic or biochemistry laboratories. Diagrams of the apparatus are included. (MR)

  18. Development of a Semester-Long, Inquiry-Based Laboratory Course in Upper-Level Biochemistry and Molecular Biology

    ERIC Educational Resources Information Center

    Murthy, Pushpalatha P. N.; Thompson, Martin; Hungwe, Kedmon

    2014-01-01

    A semester-long laboratory course was designed and implemented to familiarize students with modern biochemistry and molecular biology techniques. The designed format involved active student participation, evaluation of data, and critical thinking, and guided students to become independent researchers. The first part of the course focused on…

  19. Dairy and Biochemistry building - 1 

    E-print Network

    Photographer, if not known, put Unknown

    2009-01-01

    Scholarships Texas A&M University in partial fulfillment of the requirements of the UNIVERSITY UNDERGRADUATE RESEARCH FELLOWS April 2001 Group: Biochemistry STABILIZING THE CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFIR) BY NUCLEOTIDE... UNDERGRADUATE RESEARCH FELLOW Approved as to style and content by: C. Nick Pace (Fellows Advisor) Edward A. Funkhouser (Executive Director) April 2001 Group: Biochemistry ABSTRACT Stabilizing the Cystic Fibrosis Transmembrane Conductance Regulator...

  20. Croatian Society of Medical Biochemistry and Laboratory Medicine: national recommendations for venous blood sampling

    PubMed Central

    Nikolac, Nora; Šupak-Smol?i?, Vesna; Šimundi?, Ana-Maria; ?elap, Ivana

    2013-01-01

    Phlebotomy is one of the most complex medical procedures in the diagnosis, management and treatment of patients in healthcare. Since laboratory test results are the basis for a large proportion (60–80%) of medical decisions, any error in the phlebotomy process could have serious consequences. In order to minimize the possibility of errors, phlebotomy procedures should be standardised, well-documented and written instructions should be available at every workstation. Croatia is one of the few European countries that have national guidelines for phlebotomy, besides the universally used CLSI (Clinical Laboratory Standards Institute) H3-A6 Procedures for the Collection of Diagnostic Blood Specimens by Venipuncture; approved Standard-Sixth Edition (CLSI, 2007) and WHO (World Health Organization) guidelines on drawing blood: best practices in phlebotomy (WHO, 2010). However, the growing body of evidence in importance of preanalytical phase management resulted in a need for evidence based revision and expansion of existing recommendations. The Croatian Society for Medical Biochemistry and Laboratory Medicine, Working Group for the Preanalytical Phase issued this recommendation. This document is based on the CLSI guideline H3-A6, with significant differences and additional information. PMID:24266294

  1. Status of Undergraduate Pharmacology Laboratories in Colleges of Pharmacy in the United States

    ERIC Educational Resources Information Center

    Katz, Norman L.; And Others

    1978-01-01

    U.S. colleges of pharmacy were surveyed in 1976 to determine whether a trend exists in continuing, discontinuing, or restructuring laboratory time in pharmaceutical education. Data regarding core undergraduate pharmacology courses, undergraduate pharmacology laboratory status, and pharmacology faculty are presented. (LBH)

  2. Faculty Perspectives of Undergraduate Chemistry Laboratory: Goals and Obstacles to Success

    ERIC Educational Resources Information Center

    Bruck, Laura B.; Towns, Marcy; Bretz, Stacey Lowery

    2010-01-01

    Faculty perspectives of the undergraduate chemistry laboratory were the focus of a study to articulate the goals, strategies, and assessments used in undergraduate teaching laboratories. Data were collected via semistructured interviews with faculty (N = 22) from community colleges, liberal arts colleges, comprehensive universities, and research…

  3. Micro-Raman spectroscopy in the undergraduate research laboratory

    NASA Astrophysics Data System (ADS)

    Voor, R.; Chow, L.; Schulte, A.

    1994-05-01

    Modern materials science requires processing and characterization techniques for microscopic structures. Molecular probes such as Raman spectroscopy are some of the most viable tools, particularly if they are supplemented by imaging to obtain spatially resolved compositional information of inhomogeneous or low volume samples. In order to introduce these techniques and materials science experiments into the advanced undergraduate laboratory, we have constructed an inexpensive micro-Raman attachment, which consists of an off-the-shelf microscope and the coupling optics to an existing Raman spectrometer. The modification of the microscope, the optical coupling, and a low cost viewing system for positioning the laser excitation on the sample are described in detail. The students study molecular spectra of new materials such as diamond films, Fullerenes, and biological compounds with spatial resolution of several microns.

  4. Improved Undergraduate Astronomy Laboratories with A Modern Telescope Control System

    NASA Astrophysics Data System (ADS)

    Milano, Anthony J.; Broder, D.; Finn, R.; Newberg, H.; Weatherwax, A.; Whittet, D.

    2006-12-01

    We are in the middle of a cooperative astronomy education project to improve undergraduate laboratories at RPI (a PhD granting institution) and Siena College (a nearby liberal arts college). We have completed an overhaul of a 40-year-old, 16" B&C telescope on the RPI campus, and have made it available for hundreds of students at both schools, and once per week to the public. We have written an assessment test which was distributed to the students at the beginning and end of the Fall 2006 semester, which will be used as a baseline to determine whether the laboratory activities, which are currently under development, improve student learning in the Fall 2007 semester next year. The studio-style, hands-on, inquiry-based laboratories will be designed to challenge student misconceptions. In order to handle a large number of students using the main telescope and a limited number of smaller telescopes, we will cycle students through concurrent activities. This is enabled by the rapid acquisition and imaging of targets made possible by the upgrade to the control system of our 16" telescope. We demonstrate the productivity of our newly refurbished telescope, show the baseline results of our assessment, and present samples of activities under development. This project is funded by an NSF CCLI grant, 05-11340.

  5. Conceptualization, Development and Validation of an Instrument for Investigating Elements of Undergraduate Physics Laboratory Learning Environments: The UPLLES (Undergraduate Physics Laboratory Learning Environment Survey)

    ERIC Educational Resources Information Center

    Thomas, Gregory P; Meldrum, Al; Beamish, John

    2013-01-01

    First-year undergraduate physics laboratories are important physics learning environments. However, there is a lack of empirically informed literature regarding how students perceive their overall laboratory learning experiences. Recipe formats persist as the dominant form of instructional design in these sites, and these formats do not adequately…

  6. DNA Fingerprint Analysis of Three Short Tandem Repeat (STR) Loci for Biochemistry and Forensic Science Laboratory Courses

    ERIC Educational Resources Information Center

    McNamara-Schroeder, Kathleen; Olonan, Cheryl; Chu, Simon; Montoya, Maria C.; Alviri, Mahta; Ginty, Shannon; Love, John J.

    2006-01-01

    We have devised and implemented a DNA fingerprinting module for an upper division undergraduate laboratory based on the amplification and analysis of three of the 13 short tandem repeat loci that are required by the Federal Bureau of Investigation Combined DNA Index System (FBI CODIS) data base. Students first collect human epithelial (cheek)…

  7. Dipeptide Structural Analysis Using Two-Dimensional NMR for the Undergraduate Advanced Laboratory

    ERIC Educational Resources Information Center

    Gonzalez, Elizabeth; Dolino, Drew; Schwartzenburg, Danielle; Steiger, Michelle A.

    2015-01-01

    A laboratory experiment was developed to introduce students in either an organic chemistry or biochemistry lab course to two-dimensional nuclear magnetic resonance (2D NMR) spectroscopy using simple biomolecules. The goal of this experiment is for students to understand and interpret the information provided by a 2D NMR spectrum. Students are…

  8. Screening for Saponins Using the Blood Hemolysis Test. An Undergraduate Laboratory Experiment.

    ERIC Educational Resources Information Center

    Sotheeswaran, Subramaniam

    1988-01-01

    Describes an experiment for undergraduate chemistry laboratories involving a chemical found in plants and some sea animals. Discusses collection and identification of material, a hemolysis test, preparation of blood-coated agar plates, and application of samples. (CW)

  9. A Green Starting Material for Electrophilic Aromatic Substitution for the Undergraduate Organic Laboratory

    ERIC Educational Resources Information Center

    Jones-Wilson, T. Michelle; Burtch, Elizabeth A.

    2005-01-01

    Electrophilic aromatic substitution (EAS) experiment is designed for the second-semester and undergraduate organic chemistry laboratory. In the EAS experiment, the principles of green chemistry are discussed and illustrated in conjunction with the presentation of electrophilic aromatic substitution.

  10. Chemical Analysis of Soils: An Environmental Chemistry Laboratory for Undergraduate Science Majors.

    ERIC Educational Resources Information Center

    Willey, Joan D.; Avery, G. Brooks, Jr.; Manock, John J.; Skrabal, Stephen A.; Stehman, Charles F.

    1999-01-01

    Describes a laboratory exercise for undergraduate science students in which they evaluate soil samples for various parameters related to suitability for crop production and capability for retention of contaminants. (Contains 18 references.) (WRM)

  11. Supercontinuum Generation in Photonic Crystal Fibers for Undergraduate Laboratory

    Microsoft Academic Search

    Gregory Alan Helmininack; Derek D Gladysiewski; Feng Zhou; Ken Hershman; Ben Campbell; Jeff Thomas

    The nanotechnology field is currently undergoing an exciting period of discoveries. It is necessary to bring nanotechnology to physics students. However, there is a lack of nanotechnology experiments developed for the undergraduate labs. By coupling high peak power laser pulses to a highly nonlinear photonic crystal fiber, supercontinuum generation and characterization are incorporated into nanotechnology education in undergraduate physics labs.

  12. A Laboratory Course for Teaching Laboratory Techniques, Experimental Design, Statistical Analysis, and Peer Review Process to Undergraduate Science Students

    ERIC Educational Resources Information Center

    Gliddon, C. M.; Rosengren, R. J.

    2012-01-01

    This article describes a 13-week laboratory course called Human Toxicology taught at the University of Otago, New Zealand. This course used a guided inquiry based laboratory coupled with formative assessment and collaborative learning to develop in undergraduate students the skills of problem solving/critical thinking, data interpretation and…

  13. Planning an Objective and Need Based Curriculum: The Logistics with Reference to the Undergraduate Medical Education in Biochemistry

    PubMed Central

    Ramasamy, Ramesh; Gopal, Niranjan; Srinivasan, A R; Murugaiyan, Sathish Babu

    2013-01-01

    Purpose: The medical education is recently being transformed into several domains in order to adapt to the need and the value based academics which is required for the quality doctors who serve the community. Presently, the biochemistry curricula for the graduate students of medicine have been questioned by as many experts, because of their multiple lacunae. In this review, we would like to highlight the scenario which is related to the existing biochemistry curricula for graduate medical students, which have been followed in several medical schools and universities and we also hope to share our ideas for implementing objective and pragmatic curricula. Evidence based research, wherein the articles which are related to innovative teaching-learning tools are collected and the pros and cons which are related to the different methods analyzed in biochemistry point of view. Conclusion: Rapid changes in the content of the curriculum may not be required, but a gradual introduction of the novel approach and the methods of teaching biochemistry can be adopted into the curriculum. PMID:23634431

  14. A Project-Based Biochemistry Laboratory Promoting the Understanding and Uses of Fluorescence Spectroscopy in the Study of Biomolecular Structures and Interactions

    ERIC Educational Resources Information Center

    Briese, Nicholas; Jakubowsk, Henry V.

    2007-01-01

    A laboratory project for a first semester biochemistry course is described, which integrates the traditional classroom study of the structure and function of biomolecules with the laboratory study of these molecules using fluorescence spectroscopy. Students are assigned a specific question addressing the stability/function of lipids, proteins, or…

  15. What Are Undergraduates Doing at Biological Field Stations and Marine Laboratories?

    NSDL National Science Digital Library

    Janet Hodder (University of Oregon; Institute of Marine Biology)

    2009-09-01

    Biological field stations and marine laboratories (FSMLs) serve as places to study the natural environment in a variety of ways, from the level of the molecule to the globe. Undergraduate opportunities at FSMLs reflect the diversity of study optionsâ??formal courses, research and service internships, and field-trip experiencesâ??and students are responding to those opportunities: More than half of the FSMLs that responded to an informal survey indicated an increase in their undergraduate enrollment in the past 10 years. Many programs are residential in nature, which facilitates the development of a community of scholars in which undergraduates can interact not just with their peers but also with graduate students, research assistants, postdoctoral fellows, and resident and visiting faculty. With respect to undergraduates, challenges for FSMLs include maintaining relevance in curricular offerings, attracting rigorous and well-trained instructors, providing adequate numbers of mentors for research experiences, and providing funding to assist undergraduates who want to study at a FSML.

  16. A Comprehensive Microfluidics Device Construction and Characterization Module for the Advanced Undergraduate Analytical Chemistry Laboratory

    ERIC Educational Resources Information Center

    Piunno, Paul A. E.; Zetina, Adrian; Chu, Norman; Tavares, Anthony J.; Noor, M. Omair; Petryayeva, Eleonora; Uddayasankar, Uvaraj; Veglio, Andrew

    2014-01-01

    An advanced analytical chemistry undergraduate laboratory module on microfluidics that spans 4 weeks (4 h per week) is presented. The laboratory module focuses on comprehensive experiential learning of microfluidic device fabrication and the core characteristics of microfluidic devices as they pertain to fluid flow and the manipulation of samples.…

  17. Providing solutions through problem-based learning for the undergraduate 1st year chemistry laboratory

    Microsoft Academic Search

    Orla C. Kelly; E. Finlaysona

    A PBL laboratory-based module for first year undergraduate chemistry has been developed and successfully implemented. Its aim was to develop the students' practical and transferable skills, as well as their content knowledge and scientific understanding, and also to address the concern expressed in the literature over the effectiveness of the traditional laboratory courses to achieve these aims. The PBL module

  18. Development, Implementation, and Analysis of a National Survey of Faculty Goals for Undergraduate Chemistry Laboratory

    ERIC Educational Resources Information Center

    Bruck, Aaron D.; Towns, Marcy

    2013-01-01

    This work reports the development of a survey for laboratory goals in undergraduate chemistry, the analysis of reliable and valid data collected from a national survey of college chemistry faculty, and a synthesis of the findings. The study used a sequential exploratory mixed-methods design. Faculty goals for laboratory emerged across seven…

  19. A Survey of the Practices, Procedures, and Techniques in Undergraduate Organic Chemistry Teaching Laboratories

    ERIC Educational Resources Information Center

    Martin, Christopher B.; Schmidt, Monica; Soniat, Michael

    2011-01-01

    A survey was conducted of four-year institutions that teach undergraduate organic chemistry laboratories in the United States. The data include results from over 130 schools, describes the current practices at these institutions, and discusses the statistical results such as the scale of the laboratories performed, the chemical techniques applied,…

  20. An Undergraduate Laboratory Exercise Examining the Psychomotor Stimulant Effects of Caffeine in Laboratory Rats

    PubMed Central

    Pham, Kara; Romeo, Russell D.

    2012-01-01

    This paper describes an exercise in a Systems and Behavioral Neuroscience with Laboratory class, an introductory laboratory class taken by Barnard College students majoring in a wide range of academic topics. The study took place over three weeks, allowing students to assess the effects of caffeine on motor stimulation in laboratory rats. The within-subject design involved injecting rats with three different caffeine doses and measuring five different motor outputs in a standard open field. Students completed four different assignments related to this study, demonstrating acquisition of the stated learning goals. This lab exercise allowed students to learn about basal ganglia neural circuitry and stimulant pharmacology, to work directly with an animal model, and to generate enough data to perform statistical analyses. Course evaluations suggest that students liked learning about caffeine, a stimulant many of them have personal experience consuming. They also expressed appreciation for working with rats and for learning how to analyze data. This study can easily be implemented at most undergraduate institutions under minimal cost. The wide-ranging effects of caffeine also permit for flexibility in experimental design, allowing instructors and students options for different avenues of investigation. PMID:23504612

  1. Integrating Responsible Conduct of Research Education into Undergraduate Biochemistry and Molecular Biology Laboratory Curricula

    ERIC Educational Resources Information Center

    Hendrickson, Tamara L.

    2015-01-01

    Recently, a requirement for directed responsible conduct in research (RCR) education has become a priority in the United States and elsewhere. In the US, both the National Institutes of Health and the National Science Foundation require RCR education for all students who are financially supported by federal awards. The guidelines produced by these…

  2. Integrated Laboratories: Laying the Foundation for Undergraduate Research Experiences

    ERIC Educational Resources Information Center

    Dillner, Debra K.; Ferrante, Robert F.; Fitzgerald, Jeffrey P.; Schroeder, Maria J.

    2011-01-01

    Interest in undergraduate student research has grown in response to initiatives from various professional societies and educational organizations. Participation in research changes student attitudes towards courses as they realize the utility and relevance of what they are learning. At the U.S. Naval Academy, the chemistry majors' curriculum was…

  3. Acoustic resonance spectroscopy for the advanced undergraduate laboratory

    NASA Astrophysics Data System (ADS)

    Franco-Villafañe, J. A.; Flores-Olmedo, E.; Báez, G.; Gandarilla-Carrillo, O.; Méndez-Sánchez, R. A.

    2012-11-01

    We present a simple experiment that allows advanced undergraduates to learn the principles and applications of spectroscopy. The technique, known as acoustic resonance spectroscopy, is applied to study a vibrating rod. The setup includes electromagnetic-acoustic transducers, an audio amplifier and a vector network analyzer. Typical results of compressional, torsional and bending waves are analyzed and compared with analytical results.

  4. Cavity Ring down Spectroscopy Experiment for an Advanced Undergraduate Laboratory

    ERIC Educational Resources Information Center

    Stacewicz, T.; Wasylczyk, P.; Kowalczyk, P.; Semczuk, M.

    2007-01-01

    A simple experiment is described that permits advanced undergraduates to learn the principles and applications of the cavity ring down spectroscopy technique. The apparatus is used for measurements of low concentrations of NO[subscript 2] produced in air by an electric discharge. We present the setup, experimental procedure, data analysis and some…

  5. An undergraduate computer engineering rapid systems prototyping design laboratory

    Microsoft Academic Search

    James O. Hamblen; Henry L. Owen; Sudhakar Yalamanchili; Binh Dao

    1999-01-01

    This paper describes a new two-quarter undergraduate capstone design class in our computer engineering curriculum. Design groups comprised of students from several different areas of specialization (e.g., software systems, very large scale integration (VLSI) devices and circuits, and computer architecture) design, simulate, implement, and evaluate a complete computing system. Typical examples of projects in the current sequence include a pipelined

  6. Enhancing Undergraduate Agro-Ecological Laboratory Employment through Experiential Learning

    ERIC Educational Resources Information Center

    Grossman, J. M.; Patel, M.; Drinkwater, L. E.

    2010-01-01

    We piloted an educational model, the Sustainable Agriculture Scholars Program, linking research in organic agriculture to experiential learning activities for summer undergraduate employees in 2007 and 2008. Our objectives were to: (1) further student understanding of sustainable agriculture research, (2) increase student interest in sustainable…

  7. ATR-FTIR Spectroscopy in the Undergraduate Chemistry Laboratory: Part II--A Physical Chemistry Laboratory Experiment on Surface Adsorption

    ERIC Educational Resources Information Center

    Schuttlefield, Jennifer D.; Larsen, Sarah C.; Grassian, Vicki H.

    2008-01-01

    Attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy is a useful technique for measuring the infrared spectra of solids and liquids as well as probing adsorption on particle surfaces. The use of FTIR-ATR spectroscopy in organic and inorganic chemistry laboratory courses as well as in undergraduate research was presented…

  8. Structural Studies of Phycobiliproteins from Spirulina: Combining Spectroscopy, Thermodynamics, and Molecular Modeling in an Undergraduate Biochemistry Experiment

    NASA Astrophysics Data System (ADS)

    Taylor, Ann T. S.; Feller, Scott E.

    2002-12-01

    Molecular modeling provides a powerful mechanism for students to connect molecular-level structural changes with macroscopically observable properties. We describe an experiment that integrates spectroscopy, thermodynamics, and molecular modeling into a single activity examining structural changes in phycobiliproteins upon denaturation with urea. Phycobiliproteins contain a covalently attached chromophore, phycocyanobilin, which is constrained in a planar conformation by the folded protein. Upon denaturation of the protein, the chromophore undergoes a conformational change, leading to a significant alteration of the absorption spectrum. By measuring the absorbance at 625 nm as a function of urea concentration, the free energy of unfolding can be determined. Students determine the dihedral angles in the chromophore and map the contacts between protein and chromophore using Protein Explorer, a structure visualization program freely available on the Internet. The change in absorption wavelength can be related to the difference between the LUMO and HOMO energies, obtained using PC Spartan Pro, for the chromophore in the folded and unfolded phycobiliprotein. This experiment could be used in a physical chemistry class in a curriculum that integrates biochemistry throughout the course work as well as in a traditional biochemistry course.

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  9. Validating the Collision-Dominated Child-Langmuir Law for a DC Discharge Cathode Sheath in an Undergraduate Laboratory

    ERIC Educational Resources Information Center

    Lisovskiy, V.; Yegorenkov, V.

    2009-01-01

    In this paper, we propose a simple method of observing the collision-dominated Child-Langmuir law in the course of an undergraduate laboratory work devoted to studying the properties of gas discharges. To this end we employ the dc gas discharge whose properties are studied in sufficient detail. The undergraduate laboratory work itself is reduced…

  10. A Simple Laboratory Scale Model of Iceberg Dynamics and its Role in Undergraduate Education

    NASA Astrophysics Data System (ADS)

    Burton, J. C.; MacAyeal, D. R.; Nakamura, N.

    2011-12-01

    Lab-scale models of geophysical phenomena have a long history in research and education. For example, at the University of Chicago, Dave Fultz developed laboratory-scale models of atmospheric flows. The results from his laboratory were so stimulating that similar laboratories were subsequently established at a number of other institutions. Today, the Dave Fultz Memorial Laboratory for Hydrodynamics (http://geosci.uchicago.edu/~nnn/LAB/) teaches general circulation of the atmosphere and oceans to hundreds of students each year. Following this tradition, we have constructed a lab model of iceberg-capsize dynamics for use in the Fultz Laboratory, which focuses on the interface between glaciology and physical oceanography. The experiment consists of a 2.5 meter long wave tank containing water and plastic "icebergs". The motion of the icebergs is tracked using digital video. Movies can be found at: http://geosci.uchicago.edu/research/glaciology_files/tsunamigenesis_research.shtml. We have had 3 successful undergraduate interns with backgrounds in mathematics, engineering, and geosciences perform experiments, analyze data, and interpret results. In addition to iceberg dynamics, the wave-tank has served as a teaching tool in undergraduate classes studying dam-breaking and tsunami run-up. Motivated by the relatively inexpensive cost of our apparatus (~1K-2K dollars) and positive experiences of undergraduate students, we hope to serve as a model for undergraduate research and education that other universities may follow.

  11. Practicing biology: Undergraduate laboratory research, persistence in science, and the impact of self-efficacy beliefs

    NASA Astrophysics Data System (ADS)

    Berkes, Elizabeth

    As undergraduate laboratory research internships become more popular and universities devote considerable resources towards promoting them, it is important to clarify what students specifically gain through involvement in these experiences and it is important to understand their impact on the science pipeline. By examining recent findings describing the primary benefits of undergraduate research participation, along with self-efficacy theory, this study aims to provide more explanatory power to the anecdotal and descriptive accounts regarding the relationship between undergraduate research experiences and interest in continuing in science. Furthermore, this study characterizes practices that foster students' confidence in doing scientific work with detailed description and analysis of the interactions of researchers in a laboratory. Phase 1 of the study, a survey of undergraduate biology majors (n=71) at a major research university, investigates the relationships among participation in biology laboratory research internships, biology laboratory self-efficacy strength, and interest in persisting in science. Phase 2 of the study, a two-year investigation of a university biology research laboratory, investigates how scientific communities of practice develop self-efficacy beliefs. The findings suggest that participation in lab internships results in increased interest in continuing in life science/biology graduate school and careers. They also suggest that a significant proportion of that interest is related to the students' biology laboratory self-efficacy. The findings of this study point to two primary ways that undergraduate research participation might work to raise self-efficacy strength. First, university research laboratory communities can provide students with a variety of resources that scaffold them into biology laboratory mastery experiences. Second, university research laboratory communities can provide students with coping and mastery Discourse models and mentors, offering them access to and practice with the social norms of an epistemic community. This study begins to integrate what is currently known regarding student motivation through research experience, traditionally studied by program evaluations, with social learning theories. Given the role strong self-efficacy beliefs play in motivating students, understanding the kinds of social interactions that develop science self-efficacy could provide important policy guidelines for primary investigators who work with undergraduates, department chairs, and other promoters of undergraduate research in colleges and universities.

  12. Admission for Ph.D. study is offered to students with good undergraduate training in biochemistry, physics, organic chemistry, physical chemistry, biology, and mathematics.

    E-print Network

    Sharp, Kim

    in biochemistry, physics, organic chemistry, physical chemistry, biology, and mathematics. Students lacking Test is required; GRE Subject tests in biology, biochemistry, chemistry, physics or mathematics Hughes Medical Institute. Applicants are urged to apply for scholarships from the National Science

  13. A Capstone Experimental Learning Exercise for Undergraduate Physiology Laboratory Courses

    NSDL National Science Digital Library

    PhD Carissa M. Krane (University of Dayton Department of Biology)

    2005-12-01

    Description of a physiology laboratory course with a learning opportunity designed to extend the individual lessons performed in the laboratory course with self-directed learning through the contextual application of information in a clinical setting

  14. Assessing practical laboratory skills in undergraduate molecular biology courses

    Microsoft Academic Search

    Lynne Hunt; Annette Koenders; Vidar Gynnild

    2011-01-01

    This study explored a new strategy of assessing laboratory skills in a molecular biology course to improve: student effort in preparation for and participation in laboratory work; valid evaluation of learning outcomes; and students’ employment prospects through provision of evidence of their skills. Previously, assessment was based on written laboratory reports and examinations, not on the demonstration of practical skills

  15. Testing Plastic Deformations of Materials in the Introductory Undergraduate Mechanics Laboratory

    ERIC Educational Resources Information Center

    Romo-Kroger, C. M.

    2012-01-01

    Normally, a mechanics laboratory at the undergraduate level includes an experiment to verify compliance with Hooke's law in materials, such as a steel spring and an elastic rubber band. Stress-strain curves are found for these elements. Compression in elastic bands is practically impossible to achieve due to flaccidity. A typical experiment for…

  16. Hydrogen Storage Experiments for an Undergraduate Laboratory Course--Clean Energy: Hydrogen/Fuel Cells

    ERIC Educational Resources Information Center

    Bailey, Alla; Andrews, Lisa; Khot, Ameya; Rubin, Lea; Young, Jun; Allston, Thomas D.; Takacs, Gerald A.

    2015-01-01

    Global interest in both renewable energies and reduction in emission levels has placed increasing attention on hydrogen-based fuel cells that avoid harm to the environment by releasing only water as a byproduct. Therefore, there is a critical need for education and workforce development in clean energy technologies. A new undergraduate laboratory

  17. Cross-Disciplinary Thermoregulation and Sweat Analysis Laboratory Experiences for Undergraduate Chemistry and Exercise Science Students

    ERIC Educational Resources Information Center

    Mulligan, Gregory; Taylor, Nichole; Glen, Mary; Tomlin, Dona; Gaul, Catherine A.

    2011-01-01

    Cross-disciplinary (CD) learning experiences benefit student understanding of concepts and curriculum by offering opportunities to explore topics from the perspectives of alternate fields of study. This report involves a qualitative evaluation of CD health sciences undergraduate laboratory experiences in which concepts and students from two…

  18. The Quartz-Crystal Microbalance in an Undergraduate Laboratory Experiment: Measuring Mass

    ERIC Educational Resources Information Center

    Tsionsky, Vladimir

    2007-01-01

    The study explains the quartz-crystal microbalance (QCM) technique, which is often used as an undergraduate laboratory experiment for measuring the mass of a system. QCM can be used as a mass sensor only when the measured mass is rigidly attached to the surface.

  19. High-Performance Liquid Chromatography in the Undergraduate Chemical Engineering Laboratory

    ERIC Educational Resources Information Center

    Frey, Douglas D.; Guo, Hui; Karnik, Nikhila

    2013-01-01

    This article describes the assembly of a simple, low-cost, high-performance liquid chromatography (HPLC) system and its use in the undergraduate chemical engineering laboratory course to perform simple experiments. By interpreting the results from these experiments students are able to gain significant experience in the general method of…

  20. An Integrated Visualization and Basic Molecular Modeling Laboratory for First-Year Undergraduate Medicinal Chemistry

    ERIC Educational Resources Information Center

    Hayes, Joseph M.

    2014-01-01

    A 3D model visualization and basic molecular modeling laboratory suitable for first-year undergraduates studying introductory medicinal chemistry is presented. The 2 h practical is embedded within a series of lectures on drug design, target-drug interactions, enzymes, receptors, nucleic acids, and basic pharmacokinetics. Serving as a teaching aid…

  1. An Undergraduate Course and Laboratory in Digital Signal Processing with Field Programmable Gate Arrays

    ERIC Educational Resources Information Center

    Meyer-Base, U.; Vera, A.; Meyer-Base, A.; Pattichis, M. S.; Perry, R. J.

    2010-01-01

    In this paper, an innovative educational approach to introducing undergraduates to both digital signal processing (DSP) and field programmable gate array (FPGA)-based design in a one-semester course and laboratory is described. While both DSP and FPGA-based courses are currently present in different curricula, this integrated approach reduces the…

  2. On the Integration of Remote Experimentation into Undergraduate Laboratories-Technical Implementation

    ERIC Educational Resources Information Center

    Esche, Sven K.

    2006-01-01

    This article presents how Stevens Institute of Technology (SIT) has adopted an Internet-based approach to implement its undergraduate student laboratories. The approach allowed student interaction with the experimental devices from remote locations at any time. Furthermore, it enabled instructors to include demonstrations of sophisticated…

  3. Integrating modern instrumentation, control and information technology in the undergraduate laboratory

    Microsoft Academic Search

    L. A. Chemane; A. F. Nunes; G. P. Hancke

    1997-01-01

    This paper describes the development and implementation of a computer integrated instrumentation and control system in the undergraduate instrumentation and control laboratory of the Department of Electrical and Electronic Engineering at the University of Pretoria. It describes the process plant, the SCADA (Supervisory Control and Data Acquisition) system, the communication system, intelligent and non-intelligent I\\/O devices and field instrumentation and

  4. Simple & Rapid Generation of Complex DNA Profiles for the Undergraduate Laboratory

    ERIC Educational Resources Information Center

    Kass, David H.

    2007-01-01

    Deoxyribonucleic acid (DNA) profiles can be generated by a variety of techniques incorporating different types of DNA markers. Simple methods are commonly utilized in the undergraduate laboratory, but with certain drawbacks. In this article, the author presents an advancement of the "Alu" dimorphism technique involving two tetraplex polymerase…

  5. An Advanced Undergraduate Chemistry Laboratory Experiment Exploring NIR Spectroscopy and Chemometrics

    ERIC Educational Resources Information Center

    Wanke, Randall; Stauffer, Jennifer

    2007-01-01

    An advanced undergraduate chemistry laboratory experiment to study the advantages and hazards of the coupling of NIR spectroscopy and chemometrics is described. The combination is commonly used for analysis and process control of various ingredients used in agriculture, petroleum and food products.

  6. Glucose Transport in Cultured Animal Cells: An Exercise for the Undergraduate Cell Biology Laboratory

    ERIC Educational Resources Information Center

    Ledbetter, Mary Lee S.; Lippert, Malcolm J.

    2002-01-01

    Membrane transport is a fundamental concept that undergraduate students of cell biology understand better with laboratory experience. Formal teaching exercises commonly used to illustrate this concept are unbiological, qualitative, or intricate and time consuming to prepare. We have developed an exercise that uses uptake of radiolabeled nutrient…

  7. ATR-FTIR Spectroscopy in the Undergraduate Chemistry Laboratory: Part I--Fundamentals and Examples

    ERIC Educational Resources Information Center

    Schuttlefield, Jennifer D.; Grassian, Vicki H.

    2008-01-01

    Attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy is a useful technique for measuring the infrared spectra of solids and liquids as well as probing adsorption on particle surfaces. Several examples of the use of FTIR-ATR spectroscopy in different undergraduate chemistry laboratory courses are presented here. These…

  8. Probiotics Production: An Interesting Example for the Undergraduate Analytical Chemistry Laboratory

    Microsoft Academic Search

    Héctor C. Goicoechea; Dafna Eluk; María P. Kubescha; Julieta B. Ferraro; Beatriz M. Rodil; Hilario F. Miglietta; Víctor E. Mantovani

    2000-01-01

    An analytical chemistry laboratory experiment for undergraduates that combines traditional analytical chemistry techniques with the interdisciplinary field of biotechnology is presented. It involves a process in which the combination of a yeast (Schizosacaromyces pombe) and a bacteria (Acetobacter xylimun), usually named Kombucha, in a very simple culture of commercial black tea and glucose produces metabolites that are sampled and quantified

  9. Computation of Chemical Shifts for Paramagnetic Molecules: A Laboratory Experiment for the Undergraduate Curriculum

    ERIC Educational Resources Information Center

    Pritchard, Benjamin P.; Simpson, Scott; Zurek, Eva; Autschbach, Jochen

    2014-01-01

    A computational experiment investigating the [superscript 1]H and [superscript 13]C nuclear magnetic resonance (NMR) chemical shifts of molecules with unpaired electrons has been developed and implemented. This experiment is appropriate for an upper-level undergraduate laboratory course in computational, physical, or inorganic chemistry. The…

  10. Topics in Chemical Instrumentation: XCVIII. Experiments Involving Thermal Methods of Analysis for Undergraduate Chemistry Laboratories.

    ERIC Educational Resources Information Center

    Ewing, Galen W., Ed.

    1978-01-01

    Explains some experiments involving thermal methods of analysis for undergraduate chemistry laboratories. Some experiments are: (1) the determination of the density and degree of crystallinity of a polymer; and (2) the determination of the specific heat of a nonvolatile compound. (HM)

  11. Computer Based Learning in an Undergraduate Physics Laboratory: Interfacing and Instrument Control Using Matlab

    ERIC Educational Resources Information Center

    Sharp, J. S.; Glover, P. M.; Moseley, W.

    2007-01-01

    In this paper we describe the recent changes to the curriculum of the second year practical laboratory course in the School of Physics and Astronomy at the University of Nottingham. In particular, we describe how Matlab has been implemented as a teaching tool and discuss both its pedagogical advantages and disadvantages in teaching undergraduate

  12. Development of an Automated Modern Undergraduate Optics Laboratory using LabVIEW

    Microsoft Academic Search

    Amit Garg; Reena Sharma; Vishal Dhingra

    We report here the development of an automated modern optics laboratory for undergraduate students. This developed modern optics laboratory have automated experiments on optoelectronic device characterisation, optical instrumentation, CCD based optical experiments and advanced applications in optics. In the device characterisation section, Voltage-Current (V-I) and Optical Power-Current (P-I) characteristics of various optoelectronic devices like LEDs, Laser diodes and photo diodes

  13. Biochemistry in an undergraduate writing-intensive first-year program: Seminar courses in drugs and bioethics.

    PubMed

    Mills, Kenneth V

    2015-07-01

    The College of the Holy Cross offers a universal first-year program called Montserrat, in which first-year students participate in a living-learning experience anchored by a yearlong seminar course. The seminar courses are part of a thematic cluster of four to eight courses; students in the cluster live together in a common dormitory and participate in shared co-curricular events designed to engage the entire cluster in intellectual discourse related to the theme. A two-semester seminar within the "Natural World" cluster was offered using biochemical principles as the underlying content. In the first semester, students were introduced to drug design, activity and abuse via student presentations and guided readings on ethnobotany, drug laws, drug use in religion, and prescription drug costs. In the second semester, students discussed primary readings in ethics followed by case study analyses of assisted reproduction technologies, informed consent, genetic privacy, performance enhancing drugs and genetically modified organisms. Student learning outcomes were evaluated via rubrics and a College-facilitated survey. © 2015 by the International Union of Biochemistry and Molecular Biology, 43(4):263-272, 2015. PMID:26146792

  14. The Role of the Laboratory in Undergraduate Engineering Education

    Microsoft Academic Search

    LYLE D. FEISEL; ALBERT J. ROSA

    The function of the engineering profession is to manipulate materials, energy, and information, thereby creating benefit for humankind. To do this successfully, engineers must have a knowledge of nature that goes beyond mere theory—knowledge that is traditionally gained in educational laboratories. Over the years, however, the nature of these laboratories has changed. This paper describes the history of some of

  15. Creative Report Writing in Undergraduate Organic Chemistry Laboratory Inspires Nonmajors

    ERIC Educational Resources Information Center

    Henary, Maged; Owens, Eric A.; Tawney, Joseph G.

    2015-01-01

    Laboratory-based courses require students to compose reports based on the performed experiments to assess their overall understanding of the presented material; unfortunately, the sterile and formulated nature of the laboratory report disinterests most students. As a result, the outcome is a lower-quality product that does not reveal full…

  16. Assessing Practical Laboratory Skills in Undergraduate Molecular Biology Courses

    ERIC Educational Resources Information Center

    Hunt, Lynne; Koenders, Annette; Gynnild, Vidar

    2012-01-01

    This study explored a new strategy of assessing laboratory skills in a molecular biology course to improve: student effort in preparation for and participation in laboratory work; valid evaluation of learning outcomes; and students' employment prospects through provision of evidence of their skills. Previously, assessment was based on written…

  17. Faculty of Science: BIOCHEMISTRY AND MOLECULAR BIOLOGY

    E-print Network

    Brownstone, Rob

    Molecular Scientist Quality Control Technician Medical Illustrator Animal Care Technician ToxicologistFaculty of Science: BIOCHEMISTRY AND MOLECULAR BIOLOGY Possible Careers Laboratory Assistant and Cellular Biology - www.csbmcb.ca Association of Medical and Graduate Departments of Biochemistry (AMGDB

  18. Biochemistry chemistry &

    E-print Network

    Morgan, Stephen L.

    Biochemistry chemistry & A n A ly t i c A l B i o l o g i c A l i n o r g A n i c o r g A n i c P h of South Carolina..........................1 Department of Chemistry and Biochemistry....2 The Graduate Program in Chemistry and Biochemistry.........................................................3 Ph

  19. High Performance Liquid Chromatography Experiments to Undergraduate Laboratories

    ERIC Educational Resources Information Center

    Kissinger, Peter T.; And Others

    1977-01-01

    Reviews the principles of liquid chromatography with electrochemical detection (LCEC), an analytical technique that incorporates the advantages of both liquids chromatography and electrochemistry. Also suggests laboratory experiments using this technique. (MLH)

  20. An Enzyme Kinetics Experiment for the Undergraduate Organic Chemistry Laboratory

    ERIC Educational Resources Information Center

    Olsen, Robert J.; Olsen, Julie A.; Giles, Greta A.

    2010-01-01

    An experiment using [superscript 1]H NMR spectroscopy to observe the kinetics of the acylase 1-catalyzed hydrolysis of "N"-acetyl-DL-methionine has been developed for the organic laboratory. The L-enantiomer of the reactant is hydrolyzed completely in less than 2 h, and [superscript 1]H NMR spectroscopic data from a single sample can be worked up…

  1. Development of Sensorial Experiments and Their Implementation into Undergraduate Laboratories

    ERIC Educational Resources Information Center

    Bromfield Lee, Deborah Christina

    2009-01-01

    "Visualization" of chemical phenomena often has been limited in the teaching laboratories to the sense of sight. We have developed chemistry experiments that rely on senses other than eyesight to investigate chemical concepts, make quantitative determinations, and familiarize students with chemical techniques traditionally designed using only…

  2. Adsorption of Phosphate on Goethite: An Undergraduate Research Laboratory Project

    ERIC Educational Resources Information Center

    Tribe, Lorena; Barja, Beatriz C.

    2004-01-01

    A laboratory experiment on the adsorption of phosphate on goethite is presented, which also includes discussion on surface properties, interfaces, acid-base equilibrium, molecular structure and solid state chemistry. It was seen that many students were able to produce qualitatively correct results for a complex system of real interest and they…

  3. Creatine Synthesis: An Undergraduate Organic Chemistry Laboratory Experiment

    ERIC Educational Resources Information Center

    Smith, Andri L.; Tan, Paula

    2006-01-01

    Students in introductory chemistry classes typically appreciate seeing the connection between course content and the "real world". For this reason, we have developed a synthesis of creatine monohydrate--a popular supplement used in sports requiring short bursts of energy--for introductory organic chemistry laboratory courses. Creatine monohydrate…

  4. Genesis of "Biochemistry: A Problems Approach"

    ERIC Educational Resources Information Center

    Wood, William B.

    2002-01-01

    When the author began teaching as a young assistant professor at Caltech in 1966, his assignment was to take over the undergraduate biochemistry course taught for many years by Henry Borsook, who was about to retire. Students dreaded this course. Having delighted in biochemistry during his graduate training at Stanford, he was determined to put…

  5. Green, Enzymatic Syntheses of Divanillin and Diapocynin for the Organic, Biochemistry, or Advanced General Chemistry Laboratory

    ERIC Educational Resources Information Center

    Nishimura, Rachel T.; Giammanco, Chiara H.; Vosburg, David A.

    2010-01-01

    Environmentally benign chemistry is an increasingly important topic both in the classroom and the laboratory. In this experiment, students synthesize divanillin from vanillin or diapocynin from apocynin, using horseradish peroxidase and hydrogen peroxide in water. The dimerized products form rapidly at ambient temperature and are isolated by…

  6. Identifying a Protein by MALDI TOF Mass Spectrometry: An Experiment for the Undergraduate Laboratory

    NASA Astrophysics Data System (ADS)

    Counterman, Anne E.; Thompson, Matthew S.; Clemmer, David E.

    2003-02-01

    Matrix-assisted laser desorption ionization time-of-flight (MALDI TOF) mass spectrometry has become a valuable tool for performing routine biochemical analyses. A common procedure for protein identification involves using tryptic digestion to obtain masses of individual peptides derived from the protein. The masses are compared against an online database, and probability-based scoring systems are used to determine the closest protein matches. This article describes an experiment we have developed for an undergraduate honors general chemistry laboratory to introduce students to state-of-the-art mass spectrometric methods. Students are given an overview of the theory and instrumentation associated with MALDI TOF, and gain hands-on experience with Internet tools for protein identification using mass spectral data. The experiment would be suitable for upper-division undergraduate laboratory courses as well; appropriate modifications for this purpose are also described.

  7. Texas Tech University | Whitacre College of Engineering | Box 43103 | Lubbock, Texas 79409-3103 | 806.742.3451| www.coe.ttu.edu Undergraduate Laboratory Renovation Initiative

    E-print Network

    Gelfond, Michael

    of many of the undergraduate labs. Department of Chemical Engineering Undergraduate Teaching Labs Department of Civil and Environmental Engineering Environmental Engineering Teaching Laboratory GeotechnicalTexas Tech University | Whitacre College of Engineering | Box 43103 | Lubbock, Texas 79409

  8. The Scanning Electron Microscope As An Accelerator For The Undergraduate Advanced Physics Laboratory

    SciTech Connect

    Peterson, Randolph S. [Department of Physics and Astronomy, University of the South, 735 University Avenue, Sewanee TN 37383 (United States); Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 50 Vassar Street, Cambridge MA 01239 (United States); Berggren, Karl K.; Mondol, Mark [Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 50 Vassar Street, Cambridge MA 01239 (United States)

    2011-06-01

    Few universities or colleges have an accelerator for use with advanced physics laboratories, but many of these institutions have a scanning electron microscope (SEM) on site, often in the biology department. As an accelerator for the undergraduate, advanced physics laboratory, the SEM is an excellent substitute for an ion accelerator. Although there are no nuclear physics experiments that can be performed with a typical 30 kV SEM, there is an opportunity for experimental work on accelerator physics, atomic physics, electron-solid interactions, and the basics of modern e-beam lithography.

  9. The simulated purification of an enzyme as a `dry’ practical within an introductory course of biochemistry

    Microsoft Academic Search

    José Carlos Cameselle; Alicia Cabezas; José Canales; Mar??a Jesús Costas; Ángeles Faraldo; Ascensión Fernández; Rosa Mar??a Pinto; João Meireles Ribeiro

    2000-01-01

    This article describes a `dry-laboratory’ practical in which the multi-step purification of an enzyme is simulated. It has been devised to be implemented with beginner undergraduates taking an introductory course in biochemistry, with the aim of giving them a glimpse of the intensity of effort involved in complex, research-oriented experiments. The purification steps simulated are: preparation of a liver soluble

  10. Undergraduate Application and Scholarships

    E-print Network

    Sherrill, David

    . Organizations for Chemistry and Biochemistry Undergraduates Student Affiliates Chapter of the American Chemical Association) National Organization of Black Chemists and Chemical Engineers (NOBCChE) Women in Chemistry such as biotechnology, renewable energy, nanotechnology, modern pharmaceuticals, environmental concerns, and forensics

  11. ELISA and GC-MS as Teaching Tools in the Undergraduate Environmental Analytical Chemistry Laboratory

    NASA Astrophysics Data System (ADS)

    Wilson, Ruth I.; Mathers, Dan T.; Mabury, Scott A.; Jorgensen, Greg M.

    2000-12-01

    An undergraduate experiment for the analysis of potential water pollutants is described. Students are exposed to two complementary techniques, ELISA and GC-MS, for the analysis of a water sample containing atrazine, desethylatrazine, and simazine. Atrazine was chosen as the target analyte because of its wide usage in North America and its utility for students to predict environmental degradation products. The water sample is concentrated using solid-phase extraction for GC-MS, or diluted and analyzed using a competitive ELISA test kit for atrazine. The nature of the water sample is such that students generally find that ELISA gives an artificially high value for the concentration of atrazine. Students gain an appreciation for problems associated with measuring pollutants in the aqueous environment: sensitivity, accuracy, precision, and ease of analysis. This undergraduate laboratory provides an opportunity for students to learn several new analysis and sample preparation techniques and to critically evaluate these methods in terms of when they are most useful.

  12. Biochemistry and metabolism of lake trout: laboratory and field studies on the effects of contaminants

    USGS Publications Warehouse

    Passino, Dora R. May

    1981-01-01

    To evaluate the effects of ambient and higher concentrations of PCB's (Aroclor 1254) and DDE in food and water on fry of lake trout (Salvelinus namaycush) from Lake Michigan, I measured several biochemical indicators of stress in exposed and unexposed (control) fry. No differences between treatments were observed in oxygen consumption rates or lactate concentrations of unexercised fry, but apparent differences in specific swimming speed and lactate response in fry that swam to exhaustion suggested that exposed fry had lower stamina. Observed differences between biochemical profiles of 1-day-old sac fry reared from eggs originating from lake trout collected off Saugatuck and those originating from eggs of brood stock at the Marquette (Michigan) hatchery may have been caused by organochlorine contamination or by genetic and dietary differences between the parental stocks. Activity of the enzyme allantoinase was measured in juvenile and adult lake trout as an indicator of sublethal effects of Great Lakes contaminants. The 50% inhibition of allantoinase in vitro occurred at 6.0 mg/L Cu++, 6.7 mg/L Cd++, 34 mg/L Hg++, and 52 mg/L Pb++. Allantoinase was not affected by in vitro exposure to PCB's up to 7 ?g/g, or DDE or DDT up to 10 ?g/g; however, in vivo exposure resulting in 2.6 ?g/g PCB's in the whole fish activated allantoinase slightly (10% significance level). Allantoinase activity was negatively correlated with total length for fish from Lake Michigan but not for fish from Lake Superior or from laboratory stocks. Mercury, PCB's, and DDT, possibly acting in combination with each other and with additional contaminants, may be the cause of the negative correlation of allantoinase activity with size in Lake Michigan lake trout.

  13. A new virtual-instrumentation-based experimenting environment for undergraduate laboratories with application in research and manufacturing

    Microsoft Academic Search

    March A. Stegawski; Rolf Schaumann

    1997-01-01

    An undergraduate laboratory based on a functionally complete set of virtual tools for laboratory experimenting is described in the paper. An outstanding feature of the experimenting environment is an easy-to-use, graphical user interface to a laboratory experiment. If significantly shortens the time needed to implement experimenter-defined laboratory procedures and eliminates the need for high-level-language programming on the experimenter side. Taking

  14. So These Numbers Really Mean Something? A Role Playing Scenario-Based Approach to the Undergraduate Instrumental Analysis Laboratory

    ERIC Educational Resources Information Center

    Grannas, Amanda M.; Lagalante, Anthony F.

    2010-01-01

    A new curricular approach in our undergraduate second-year instrumental analysis laboratory was implemented. Students work collaboratively on scenarios in diverse fields including pharmaceuticals, forensics, gemology, art conservation, and environmental chemistry. Each laboratory section (approximately 12 students) is divided into three groups…

  15. Microwave-Enhanced Organic Syntheses for the Undergraduate Laboratory: Diels-Alder Cycloaddition, Wittig Reaction, and Williamson Ether Synthesis

    ERIC Educational Resources Information Center

    Baar, Marsha R.; Falcone, Danielle; Gordon, Christopher

    2010-01-01

    Microwave heating enhanced the rate of three reactions typically performed in our undergraduate organic chemistry laboratory: a Diels-Alder cycloaddition, a Wittig salt formation, and a Williamson ether synthesis. Ninety-minute refluxes were shortened to 10 min using a laboratory-grade microwave oven. In addition, yields improved for the Wittig…

  16. Chemoenzymatic Synthesis of an Enantiomerically Pure Lactone: A Three-Step Synthesis for Undergraduate Organic Chemistry Laboratory

    Microsoft Academic Search

    Cynthia K. McClure; H. Keith Chenault

    1996-01-01

    A three-step laboratory sequence for the undergraduate organic laboratory is described. This series of experiments requires a student to use the product from one reaction as the starting material for a subsequent reaction, and thus the affords the student a \\

  17. Update on Improved Undergraduate Astronomy Laboratories with a Modern Telescope Control System

    NASA Astrophysics Data System (ADS)

    Jacobi, Ian; Broder, D.; Finn, R.; Milano, A. J.; Newberg, H.; Weatherwax, A.; Whittet, D.

    2007-12-01

    We are completing a cooperative astronomy education project designed to improve undergraduate laboratories at RPI (a PhD granting institution) and Siena College (a nearby liberal arts college). Following the overhaul of a 40-year-old, 16" B&C telescope on the RPI campus, we have made it available for use for hundreds of students at both schools and once per week to the public. This telescope has been integrated into studio-style, hands-on, inquiry-based laboratories designed to challenge student misconceptions. An assessment test was designed and distributed to the students taking the course at the beginning and end of the Fall 2007 semester, the results of which we compare to a baseline study undertaken in Fall 2006 and Spring 2007 to determine the efficacy of the laboratories in improving undergraduate astronomy education. In order to handle a large number of students using the main telescope and a limited number of smaller telescopes, we have cycled students through concurrent activites. This has been enabled by the rapid acquisition and imaging of targets made possible by the upgrade to the control system of our 16" telescope. We show preliminary results of the Fall 2007 assessments and comparisons to the baseline assessment. This project is funded by an NSF CCLI grant, 05-11340.

  18. Inexpensive high-precision capacitance measurements and their applications in undergraduate laboratories

    NASA Astrophysics Data System (ADS)

    Clayhold, Jeffrey; Priest, Joseph

    2008-12-01

    An inexpensive system for precision capacitance measurement is presented. The system is appropriate for undergraduate laboratories is based on a newly available capacitance-to-digital integrated circuit that can measure picofarad capacitances to six significant figures. The circuitry software for controlling the integrated circuit with a personal computer via an I2C interface bus are described. Examples of experiments that make use of the circuitry are discussed, including a novel hydrostatic magnetometer that uses precision capacitance measurement to determine the magnetization of a small sample.

  19. Undergraduate Laboratory Module for Implementing ELISA on the High Performance Microfluidic Platform

    PubMed Central

    Giri, Basant; Peesara, Ravichander R.; Yanagisawa, Naoki; Dutta, Debashis

    2015-01-01

    Implementing enzyme-linked immunosorbent assays (ELISA) in microchannels offers several advantages over its traditional microtiter plate-based format, including a reduced sample volume requirement, shorter incubation period, and greater sensitivity. Moreover, microfluidic ELISA platforms are inexpensive to fabricate and allow integration of analytical procedures, such as sample preconcentration, that further enhance the performance of the immunoassay. In view of the scientific potential of microfluidic ELISAs, inclusion of this technique into an undergraduate curriculum is valuable in preparing the next generation of scientists and engineers. Here, an experimental module is presented for this immunoassay method that can be completed in an undergraduate laboratory setting within two 3-h periods (including all incubation and data analyses procedures) using only a microliter of sample and reagents per assay. In addition to acquainting students with the microfluidic technology, the reported module provides training in quantitating ELISAs using the kinetic format of the assay. Furthermore, it offers a useful educational tool for introducing undergraduates to basic image analysis techniques, as well as signal-to-noise ratio and limit of detection calculations that are valuable in characterizing any analytical method. PMID:26052160

  20. Undergraduate programmes in o Biochemistry

    E-print Network

    Miall, Chris

    and environmental health, medicine and food security. Professor Steve Busby Head of School of Biosciences Challenge an offer, I am looking forward to meet you. Professor Steve Busby Head of School of Biosciences Dr Klaus

  1. Chemistry & Biochemistry UNDERGRADUATE PRECEPTOR CONTRACT

    E-print Network

    Ziurys, Lucy M.

    a specific discussion of the time per week budgeted for described activities (minimum three hours be checked under each unit section, based on the number of units requested above): One Unit requires) or a timeline describing 45 hours of total activity per semester

  2. CLINICAL BIOCHEMISTRY

    EPA Science Inventory

    Assessment of the health status of animals through measurement of cellular, biochemical, and macromolecular constituents in blood, secretions, and excretions has been variously referred to as clinical chemistry, clinical biochemistry, or clinical pathology. he genesis of this dis...

  3. Analysis of the Essential Nutrient Strontium in Marine Aquariums by Atomic Absorption Spectroscopy: An Undergraduate Analytical Chemistry Laboratory Exercise

    NASA Astrophysics Data System (ADS)

    Gilles de Pelichy, Laurent D.; Adam, Carl; Smith, Eugene T.

    1997-10-01

    An undergraduate atomic absorption spectroscopy (AAS) laboratory experiment is presented involving the analysis of the essential nutrient strontium in a real-life sample, sea water. The quantitative analysis of strontium in sea water is a problem well suited for an undergraduate analytical chemistry laboratory. Sea water contains numerous components which prevent the direct quantitative determination of strontium. Students learn first hand about the role of interferences in analytical measurements, and about the method of standard addition which is used to minimize these effects. This laboratory exercise also introduces undergraduate students to practical problems associated with AAS. We encourage students as a part of this experiment to collect and analyze marine water samples from local pet shops.

  4. A new virtual-instrumentation-based experimenting environment for undergraduate laboratories with application in research and manufacturing

    Microsoft Academic Search

    M. A. Stegawski; R. Schaumann

    1998-01-01

    An undergraduate laboratory based on a functionally complete set of virtual tools for experimenting is described in this paper. An outstanding feature of the experimenting environment is an easy-to-use, graphical user interface to a laboratory experiment. It significantly shortens the time needed to implement experimenter-defined laboratory procedures and eliminates the need for high-level-language programming on the experimenter side. Taking advantage

  5. Safety in the Chemical Laboratory: Learning How to Run Safer Undergraduate Laboratories.

    ERIC Educational Resources Information Center

    Mohrig, Jerry R.

    1983-01-01

    Discusses responsibilities for providing safe experiments and for teaching about safety. Provides lists of references on chemical safety and regulated/potential carcinogens. Also discusses general laboratory safety procedures including waste disposal and recycling of solvents. (JM)

  6. Development of a Green Fluorescent Protein-Based Laboratory Curriculum

    ERIC Educational Resources Information Center

    Larkin, Patrick D.; Hartberg, Yasha

    2005-01-01

    A laboratory curriculum has been designed for an undergraduate biochemistry course that focuses on the investigation of the green fluorescent protein (GFP). The sequence of procedures extends from analysis of the DNA sequence through PCR amplification, recombinant plasmid DNA synthesis, bacterial transformation, expression, isolation, and…

  7. A Response to "BIO 2010: Transforming Undergraduate Education for Future Research Biologists," from the Perspective of the Biochemistry and Molecular Biology Major Program at Kenyon College

    ERIC Educational Resources Information Center

    Slonczewski, Joan L.; Marusak, Rosemary

    2004-01-01

    The National Research Council completed a major study of undergraduate biology education, "BIO 2010-Transforming Undergraduate Education For Future Research Biologists (BIO 2010)," funded by the Howard Hughes Medical Institute and the National Institutes of Health. The "BIO 2010" report recommends that biology pedagogy should use an…

  8. Incorporating a collaborative web-based virtual laboratory in an undergraduate bioinformatics course.

    PubMed

    Weisman, David

    2010-01-01

    Face-to-face bioinformatics courses commonly include a weekly, in-person computer lab to facilitate active learning, reinforce conceptual material, and teach practical skills. Similarly, fully-online bioinformatics courses employ hands-on exercises to achieve these outcomes, although students typically perform this work offsite. Combining a face-to-face lecture course with a web-based virtual laboratory presents new opportunities for collaborative learning of the conceptual material, and for fostering peer support of technical bioinformatics questions. To explore this combination, an in-person lecture-only undergraduate bioinformatics course was augmented with a remote web-based laboratory, and tested with a large class. This study hypothesized that the collaborative virtual lab would foster active learning and peer support, and tested this hypothesis by conducting a student survey near the end of the semester. Respondents broadly reported strong benefits from the online laboratory, and strong benefits from peer-provided technical support. In comparison with traditional in-person teaching labs, students preferred the virtual lab by a factor of two. Key aspects of the course architecture and design are described to encourage further experimentation in teaching collaborative online bioinformatics laboratories. PMID:21567782

  9. Laboratory Techniques in Geology: Embedding Analytical Methods into the Undergraduate Curriculum

    NASA Astrophysics Data System (ADS)

    Baedke, S. J.; Johnson, E. A.; Kearns, L. E.; Mazza, S. E.; Gazel, E.

    2014-12-01

    Paid summer REU experiences successfully engage undergraduate students in research and encourage them to continue to graduate school and scientific careers. However these programs only accommodate a limited number of students due to funding constraints, faculty time commitments, and limited access to needed instrumentation. At JMU, the Department of Geology and Environmental Science has embedded undergraduate research into the curriculum. Each student fulfilling a BS in Geology or a BA in Earth Science completes 3 credits of research, including a 1-credit course on scientific communication, 2 credits of research or internship, followed by a presentation of that research. Our department has successfully acquired many analytical instruments and now has an XRD, SEM/EDS, FTIR, handheld Raman, AA, ion chromatograph, and an IRMS. To give as many students as possible an overview to the scientific uses and operation methods for these instruments, we revived a laboratory methods course that includes theory and practical use of instrumentation at JMU, plus XRF sample preparation and analysis training at Virginia Tech during a 1-day field trip. In addition to practical training, projects included analytical concepts such as evaluating analytical vs. natural uncertainty, determining error on multiple measurements, signal-to-noise ratio, and evaluating data quality. State funding through the 4-VA program helped pay for analytical supplies and support for students to complete research projects over the summer or during the next academic year using instrumentation from the course. This course exemplifies an alternative path to broadening participation in undergraduate research and creating stronger partnerships between PUI's and research universities.

  10. The ATLAS project: The effects of a constructionist digital laboratory project on undergraduate laboratory performance.

    PubMed

    Shoepe, Todd C; Cavedon, Dana K; Derian, Joseph M; Levy, Celine S; Morales, Amy

    2015-01-01

    Anatomical education is a dynamic field where developments in the implementation of constructive, situated-learning show promise in improving student achievement. The purpose of this study was to examine the effectiveness of an individualized, technology heavy project in promoting student performance in a combined anatomy and physiology laboratory course. Mixed-methods research was used to compare two cohorts of anatomy laboratories separated by the adoption of a new laboratory atlas project, which were defined as preceding (PRE) and following the adoption of the Anatomical Teaching and Learning Assessment Study (ATLAS; POST). The ATLAS project required the creation of a student-generated, photographic atlas via acquisition of specimen images taken with tablet technology and digital microscope cameras throughout the semester. Images were transferred to laptops, digitally labeled and photo edited weekly, and compiled into a digital book using Internet publishing freeware for final project submission. An analysis of covariance confirmed that student final examination scores were improved (P < 0.05) following the implementation of the laboratory atlas project (PRE, n = 75; POST, n = 90; means ± SE; 74.9 ± 0.9 versus 78.1 ± 0.8, respectively) after controlling for cumulative student grade point average. Analysis of questionnaires collected (n = 68) from the post group suggested students identified with atlas objectives, appreciated the comprehensive value in final examination preparation, and the constructionism involved, but recommended alterations in assignment logistics and the format of the final version. Constructionist, comprehensive term-projects utilizing student-preferred technologies could be used to improve performance toward student learning outcomes. PMID:24678042

  11. Demand for interdisciplinary laboratories for physiology research by undergraduate students in biosciences and biomedical engineering.

    PubMed

    Clase, Kari L; Hein, Patrick W; Pelaez, Nancy J

    2008-12-01

    Physiology as a discipline is uniquely positioned to engage undergraduate students in interdisciplinary research in response to the 2006-2011 National Science Foundation Strategic Plan call for innovative transformational research, which emphasizes multidisciplinary projects. To prepare undergraduates for careers that cross disciplinary boundaries, students need to practice interdisciplinary communication in academic programs that connect students in diverse disciplines. This report surveys policy documents relevant to this emphasis on interdisciplinary training and suggests a changing role for physiology courses in bioscience and engineering programs. A role for a physiology course is increasingly recommended for engineering programs, but the study of physiology from an engineering perspective might differ from the study of physiology as a basic science. Indeed, physiology laboratory courses provide an arena where biomedical engineering and bioscience students can apply knowledge from both fields while cooperating in multidisciplinary teams under specified technical constraints. Because different problem-solving approaches are used by students of engineering and bioscience, instructional innovations are needed to break down stereotypes between the disciplines and create an educational environment where interdisciplinary teamwork is used to bridge differences. PMID:19047501

  12. CO(2) rebreathing: an undergraduate laboratory to study the chemical control of breathing.

    PubMed

    Domnik, N J; Turcotte, S E; Yuen, N Y; Iscoe, S; Fisher, J T

    2013-12-01

    The Read CO2 rebreathing method (Read DJ. A clinical method for assessing the ventilatory response to carbon dioxide. Australas Ann Med 16: 20-32, 1967) provides a simple and reproducible approach for studying the chemical control of breathing. It has been widely used since the modifications made by Duffin and coworkers. Our use of a rebreathing laboratory to challenge undergraduate science students to investigate the control of breathing provided 8 yr of student-generated data for comparison with the literature. Students (age: 19-22 yr, Research Ethics Board approval) rebreathed from a bag containing 5% CO2 and 95% O2 (to suppress the peripheral chemoreflex to hypoxia). Rebreathing was performed, and ventilation measured, after hyperventilation to deplete tissue CO2 stores and enable the detection of the central chemoreflex threshold. We analyzed 43 data sets, of which 10 were rejected for technical reasons. The mean threshold and ventilatory sensitivity to CO2 were 43.3 ± 3.8 mmHg and 4.60 ± 3.04 l·min(-1)·mmHg(-1) (means ± SD), respectively. Threshold values were normally distributed, whereas sensitivity was skewed to the left. Both mean values agreed well with those in the literature. We conclude that the modified rebreathing protocol is a robust method for undergraduate investigation of the chemical control of breathing. PMID:24292914

  13. The Cyclohexanol Cycle and Synthesis of Nylon 6,6: Green Chemistry in the Undergraduate Organic Laboratory

    ERIC Educational Resources Information Center

    Dintzner, Matthew R.; Kinzie, Charles R.; Pulkrabek, Kimberly; Arena, Anthony F.

    2012-01-01

    A one-term synthesis project that incorporates many of the principles of green chemistry is presented for the undergraduate organic laboratory. In this multistep scheme of reactions, students react, recycle, and ultimately convert cyclohexanol to nylon 6,6. The individual reactions in the project employ environmentally friendly methodologies, and…

  14. Oxidation of Borneol to Camphor Using Oxone and Catalytic Sodium Chloride: A Green Experiment for the Undergraduate Organic Chemistry Laboratory

    ERIC Educational Resources Information Center

    Lang, Patrick T.; Harned, Andrew M.; Wissinger, Jane E.

    2011-01-01

    A new green oxidation procedure was developed for the undergraduate organic teaching laboratories using Oxone and a catalytic quantity of sodium chloride for the conversion of borneol to camphor. This simple 1 h, room temperature reaction afforded high quality and yield of product, was environmentally friendly, and produced negligible quantities…

  15. The Synthesis of 1-Phenyl-1,2,3,4-tetrahydroisoquinolines: An Undergraduate Organic Laboratory Experiment and Class Project.

    ERIC Educational Resources Information Center

    Letcher, R. M.; Sammes, M. P.

    1985-01-01

    Describes an undergraduate organic chemistry experiment (requiring three/four 3-hour laboratory sessions) involving a four-stage synthesis of 1-phenyl-1,2,3,4-tetrahydroisoquinolines via the Pictet-Spengler route. In addition, the experiment allows students to study the spectra and properties of aklaloid-like materials while completing several…

  16. Red Seaweed Enzyme-Catalyzed Bromination of Bromophenol Red: An Inquiry-Based Kinetics Laboratory Experiment for Undergraduates

    ERIC Educational Resources Information Center

    Jittam, Piyachat; Boonsiri, Patcharee; Promptmas, Chamras; Sriwattanarothai, Namkang; Archavarungson, Nattinee; Ruenwongsa, Pintip; Panijpan, Bhinyo

    2009-01-01

    Haloperoxidase enzymes are of interest for basic and applied bioscientists because of their increasing importance in pharmaceutical industry and environmental cleanups. In a guided inquiry-based laboratory experiment for life-science, agricultural science, and health science undergraduates, the bromoperoxidase from a red seaweed was used to…

  17. Nickel-Catalyzed Suzuki-Miyaura Cross-Coupling in a Green Alcohol Solvent for an Undergraduate Organic Chemistry Laboratory

    ERIC Educational Resources Information Center

    Hie, Liana; Chang, Jonah J.; Garg, Neil K.

    2015-01-01

    A modern undergraduate organic chemistry laboratory experiment involving the Suzuki-Miyaura coupling is reported. Although Suzuki-Miyaura couplings typically employ palladium catalysts in environmentally harmful solvents, this experiment features the use of inexpensive nickel catalysis, in addition to a "green" alcohol solvent. The…

  18. SIPCAn (Separation, Isolation, Purification, Characterization, and Analysis): A One-Term, Integrated Project for the Undergraduate Organic Laboratory

    ERIC Educational Resources Information Center

    Dintzner, Matthew R.; Kinzie, Charles R.; Pulkrabek, Kimberly A.; Arena, Anthony F.

    2011-01-01

    SIPCAn, an acronym for separation, isolation, purification, characterization, and analysis, is presented as a one-term, integrated project for the first-term undergraduate organic laboratory course. Students are assigned two mixtures of unknown organic compounds--a mixture of two liquid compounds and a mixture of two solid compounds--at the…

  19. Gold Electrodes Modified with Self-Assembled Monolayers for Measuring L-Ascorbic Acid: An Undergraduate Analytical Chemistry Laboratory Experiment

    ERIC Educational Resources Information Center

    Ito, Takashi; Perera, D. M. Neluni T.; Nagasaka, Shinobu

    2008-01-01

    This article describes an undergraduate electrochemistry laboratory experiment in which the students measure the L-ascorbic acid content of a real sample. Gold electrodes modified with self-assembled monolayers (SAMs) of thioctic acid and cysteamine are prepared to study the effects of surface modification on the electrode reaction of L-ascorbic…

  20. Ab Initio Determinations of Photoelectron Spectra Including Vibronic Features: An Upper-Level Undergraduate Physical Chemistry Laboratory

    ERIC Educational Resources Information Center

    Lord, Richard L.; Davis, Lisa; Millam, Evan L.; Brown, Eric; Offerman, Chad; Wray, Paul; Green, Susan M. E.

    2008-01-01

    We present a first-principles determination of the photoelectron spectra of water and hypochlorous acid as a laboratory exercise accessible to students in an undergraduate physical chemistry course. This paper demonstrates the robustness and user-friendliness of software developed for the Franck-Condon factor calculation. While the calculator is…

  1. Validating the Goldstein-Wehner Law for the Stratified Positive Column of DC Discharge in an Undergraduate Laboratory

    ERIC Educational Resources Information Center

    Lisovskiy, V. A.; Koval, V. A.; Artushenko, E. P.; Yegorenkov, V. D.

    2012-01-01

    In this paper we suggest a simple technique for validating the Goldstein-Wehner law for a stratified positive column of dc glow discharge while studying the properties of gas discharges in an undergraduate laboratory. To accomplish this a simple device with a pre-vacuum mechanical pump, dc source and gas pressure gauge is required. Experiments may…

  2. Acoustic impulse response method as a source of undergraduate research projects and advanced laboratory experiments.

    PubMed

    Robertson, W M; Parker, J M

    2012-03-01

    A straightforward and inexpensive implementation of acoustic impulse response measurement is described utilizing the signal processing technique of coherent averaging. The technique is capable of high signal-to-noise measurements with personal computer data acquisition equipment, an amplifier/speaker, and a high quality microphone. When coupled with simple waveguide test systems fabricated from commercial PVC plumbing pipe, impulse response measurement has proven to be ideal for undergraduate research projects-often of publishable quality-or for advanced laboratory experiments. The technique provides important learning objectives for science or engineering students in areas such as interfacing and computer control of experiments; analog-to-digital conversion and sampling; time and frequency analysis using Fourier transforms; signal processing; and insight into a variety of current research areas such as acoustic bandgap materials, acoustic metamaterials, and fast and slow wave manipulation. PMID:22423798

  3. Design and construction of a two-temperature preference behavioral assay for undergraduate neuroscience laboratories.

    PubMed

    Daniels, Richard L; McKemy, David D

    2010-01-01

    Behavioral assays in the undergraduate neuroscience laboratory are useful for illustrating a variety of physiological concepts. An example is homeostatic temperature regulation (thermoregulation). Many model organisms, from flies to mice, regulate internal temperatures in part by moving to suitable climates (thermotaxis). A particularly reliable method of quantifying temperature-dependent thermotactic behaviors is the two-temperature preference behavioral assay. In this preparation, an organism is free to move between two temperature-controlled surfaces, thus revealing its preferred thermal environment. Here we present the design and construction of a two-temperature preference assay chamber. The device uses Peltier-based thermoelectric modules (TECs) for heating and cooling, and is capable of precision control of temperatures from -5ºC to 60ºC. Our approach can be easily adapted for use in a variety of physiological and behavioral assays that require precise temperature control over a wide range of temperatures. PMID:23494724

  4. Design and Construction of a Two-Temperature Preference Behavioral Assay for Undergraduate Neuroscience Laboratories

    PubMed Central

    Daniels, Richard L.; McKemy, David D.

    2010-01-01

    Behavioral assays in the undergraduate neuroscience laboratory are useful for illustrating a variety of physiological concepts. An example is homeostatic temperature regulation (thermoregulation). Many model organisms, from flies to mice, regulate internal temperatures in part by moving to suitable climates (thermotaxis). A particularly reliable method of quantifying temperature-dependent thermotactic behaviors is the two-temperature preference behavioral assay. In this preparation, an organism is free to move between two temperature-controlled surfaces, thus revealing its preferred thermal environment. Here we present the design and construction of a two-temperature preference assay chamber. The device uses Peltier-based thermoelectric modules (TECs) for heating and cooling, and is capable of precision control of temperatures from ?5ºC to 60ºC. Our approach can be easily adapted for use in a variety of physiological and behavioral assays that require precise temperature control over a wide range of temperatures. PMID:23494724

  5. Functional Magnetic Resonance Imaging (fMRI): A Brief Exercise for an Undergraduate Laboratory Course.

    PubMed

    Hurd, Mark W; Vincent, Diana J

    2006-01-01

    Functional neuroimaging represents an important technique for the study of the brain. However, the skills necessary for collecting, processing, and analyzing functional magnetic resonance imaging (fMRI) data sets are complex and relatively few undergraduate programs offer students an opportunity to acquire these skills or to observe functional neuroimaging. We report here on our experiences working with functional neuroimaging in an undergraduate laboratory course and suggest resources for the implementation of a similar exercise in a comparable setting. This exercise is structured so that four class meetings are devoted to functional neuroimaging. During these sessions, we discuss the basics of fMRI, study design, the advantages and disadvantages of this technique for the study of brain function as well as a general overview of data processing and analysis. Due to the college's proximity to a medical school, we are able to offer students an opportunity to observe functional neuroimaging sessions (however, this component is not critical for the completion of this exercise). Two final class sessions are devoted to data processing and presentation as well as writing up the experimental results. The exercise culminates in a paper based on the American Psychological Association format for a small number of subjects. At the conclusion of the exercise, students were surveyed to assess their impressions of the lab sessions. The results from these surveys indicate that students found this portion of the laboratory course to be a very positive experience. While this lab exercise does require some initial set up, we believe it stimulates the development of critical thinking skills with a technique that is used increasingly in neuroscience research. Both print and online resources are suggested to assist faculty in setting up a similar exercise. PMID:23493760

  6. Transposing from the laboratory to the classroom to generate authentic research experiences for undergraduates.

    PubMed

    Burnette, James M; Wessler, Susan R

    2013-02-01

    Large lecture classes and standardized laboratory exercises are characteristic of introductory biology courses. Previous research has found that these courses do not adequately convey the process of scientific research and the excitement of discovery. Here we propose a model that provides beginning biology students with an inquiry-based, active learning laboratory experience. The Dynamic Genome course replicates a modern research laboratory focused on eukaryotic transposable elements where beginning undergraduates learn key genetics concepts, experimental design, and molecular biological skills. Here we report on two key features of the course, a didactic module and the capstone original research project. The module is a modified version of a published experiment where students experience how virtual transposable elements from rice (Oryza sativa) are assayed for function in transgenic Arabidopsis thaliana. As part of the module, students analyze the phenotypes and genotypes of transgenic plants to determine the requirements for transposition. After mastering the skills and concepts, students participate in an authentic research project where they use computational analysis and PCR to detect transposable element insertion site polymorphism in a panel of diverse maize strains. As a consequence of their engagement in this course, students report large gains in their ability to understand the nature of research and demonstrate that they can apply that knowledge to independent research projects. PMID:23172853

  7. Transposing from the Laboratory to the Classroom to Generate Authentic Research Experiences for Undergraduates

    PubMed Central

    Burnette, James M.; Wessler, Susan R.

    2013-01-01

    Large lecture classes and standardized laboratory exercises are characteristic of introductory biology courses. Previous research has found that these courses do not adequately convey the process of scientific research and the excitement of discovery. Here we propose a model that provides beginning biology students with an inquiry-based, active learning laboratory experience. The Dynamic Genome course replicates a modern research laboratory focused on eukaryotic transposable elements where beginning undergraduates learn key genetics concepts, experimental design, and molecular biological skills. Here we report on two key features of the course, a didactic module and the capstone original research project. The module is a modified version of a published experiment where students experience how virtual transposable elements from rice (Oryza sativa) are assayed for function in transgenic Arabidopsis thaliana. As part of the module, students analyze the phenotypes and genotypes of transgenic plants to determine the requirements for transposition. After mastering the skills and concepts, students participate in an authentic research project where they use computational analysis and PCR to detect transposable element insertion site polymorphism in a panel of diverse maize strains. As a consequence of their engagement in this course, students report large gains in their ability to understand the nature of research and demonstrate that they can apply that knowledge to independent research projects. PMID:23172853

  8. Electroretinograms in Drosophila: A Robust and Genetically Accessible Electrophysiological System for the Undergraduate Laboratory

    PubMed Central

    Vilinsky, Ilya; Johnson, Karl G.

    2012-01-01

    Laboratory courses in neurophysiology fulfill a critical need for inquiry-based training in undergraduate programs in neuroscience and biology. These courses typically use classical electrophysiological preparations to explore the basic features of neuronal function. However, current neuroscience research also focuses on elucidating the molecular and genetic mechanisms of neuronal function, using model systems that include mutant and transgenic animals. To bridge laboratory training in neurophysiology with modern molecular genetics, we describe a teaching model based on electroretinography of the fruit fly Drosophila melanogaster, a long-established model system for basic neuroscience research. Drosophila are easily maintained, economical, and have hundreds of neurophysiologically relevant mutant strains and genetic tools readily available. The Drosophila electroretinogram (ERG) is a simple and accessible extracellular recording of a neural signal in the fly eye in response to flashes of light. The signal is multifaceted and the response is sensitive to stimulation parameters such as intensity, duration and wavelength, thus forming a rich source of analysis for students. Most importantly, different mutations affecting key components of intracellular signaling, synaptic transmission or neuronal function can affect the ERG waveform in characteristic ways. Recording wild type and mutant ERGs allows students to examine firsthand the connection between genetics, biochemical pathways, and electrophysiology. This neurophysiology laboratory course can facilitate and enhance an understanding of the cellular and molecular contributions to neurophysiological recordings. PMID:23494679

  9. Designing Laboratory Exercises for the Undergraduate Molecular Biology/Biochemistry Student: Techniques and Ethical Implications Involved in Personalized Medicine

    ERIC Educational Resources Information Center

    Weinlander, Kenneth M.; Hall, David J.

    2010-01-01

    Personalized medicine refers to medical care that involves genetically screening patients for their likelihood to develop various disorders. Commercial genome screening only involves identifying a consumer's genotype for a few single nucleotide polymorphisms. A phenotype (such as an illness) is greatly influenced by three factors: genes, gene…

  10. Synthesis of a Partially Protected Azidodeoxy Sugar. A Project Suitable for the Advanced Undergraduate Organic Chemistry Laboratory

    NASA Astrophysics Data System (ADS)

    Norris, Peter; Freeze, Scott; Gabriel, Christopher J.

    2001-01-01

    The synthetic chemistry of carbohydrates provides a wealth of possible experiments for the undergraduate organic chemistry laboratory. However, few appropriate examples have been developed to date. With this simple two-step synthesis of a partially protected azidodeoxy sugar, we demonstrate several important concepts introduced in undergraduate chemistry (alcohol activation, steric hindrance, nucleophilic substitution) while offering products that are readily amenable to analysis by high field NMR. Students are exposed to techniques such as monitoring reactions by TLC, workup of reaction mixtures, and isolation by flash chromatography. Suitable methods for analysis of products include NMR, IR, MS, and polarimetry.

  11. Chiral Compounds and Green Chemistry in Undergraduate Organic Laboratories: Reduction of a Ketone by Sodium Borohydride and Baker's Yeast

    NASA Astrophysics Data System (ADS)

    Pohl, Nicola; Clague, Allen; Schwarz, Kimberly

    2002-06-01

    We describe an integrated set of experiments for the undergraduate organic laboratory that allows students to compare and contrast biological and chemical means of introducing chirality into a molecule. The racemic reduction of ethyl acetoacetate with sodium borohydride and the same reduction in the presence of a tartaric acid ligand are described, and a capillary gas chromatography column packed with a chiral material for product analysis is introduced. The results of these two hydride reactions are compared with the results of a common undergraduate experiment, the baker's yeast reduction of ethyl acetoacetate.

  12. CHEMISTRY 474/674 STRUCTURAL AND PHYSICAL BIOCHEMISTRY

    E-print Network

    Mather, Patrick T.

    1 CHEMISTRY 474/674 STRUCTURAL AND PHYSICAL BIOCHEMISTRY Fall 2013 J. C. Dabrowiak Office: 2-016D.syr.edu The Course: CHE 474/674 covers basic physical chemistry for the undergraduate biochemistry/physical science important physical and structural properties of DNA and RNA and covers chemical kinetics and its application

  13. Using Field Trips and Field-Based Laboratories to Teach Undergraduate Soil Science

    NASA Astrophysics Data System (ADS)

    Brevik, Eric C.; Steffan, Joshua; Hopkins, David

    2015-04-01

    Classroom activities can provide important background information allowing students to understand soils. However, soils are formed in nature; therefore, understanding their properties and spatial relationships in the field is a critical component for gaining a comprehensive and holistic understanding of soils. Field trips and field-based laboratories provide students with the field experiences and skills needed to gain this understanding. Field studies can 1) teach students the fundamentals of soil descriptions, 2) expose students to features (e.g., structure, redoximorphic features, clay accumulation, etc.) discussed in the classroom, and 3) allow students to verify for themselves concepts discussed in the more theoretical setting of the classroom. In each case, actually observing these aspects of soils in the field reinforces and improves upon classroom learning and comprehension. In addition, the United States Department of Agriculture's Natural Resources Conservation Service has identified a lack of fundamental field skills as a problem when they hire recent soil science graduates, thereby demonstrating the need for increased field experiences for the modern soil science student. In this presentation we will provide examples of field trips and field-based laboratories that we have designed for our undergraduate soil science classes, discuss the learning objectives, and provide several examples of comments our students have made in response to these field experiences.

  14. Designing Polymerase Chain Reaction (PCR) Primer Multiplexes in the Forensic Laboratory

    ERIC Educational Resources Information Center

    Elkins, Kelly M.

    2011-01-01

    The polymerase chain reaction (PCR) is a common experiment in upper-level undergraduate biochemistry, molecular biology, and forensic laboratory courses as reagents and thermocyclers have become more affordable for institutions. Typically, instructors design PCR primers to amplify the region of interest and the students prepare their samples for…

  15. Argument-Driven Inquiry: Using the Laboratory to Improve Undergraduates' Science Writing Skills through Meaningful Science Writing, Peer-Review, and Revision

    ERIC Educational Resources Information Center

    Walker, Joi Phelps; Sampson, Victor

    2013-01-01

    This paper presents preliminary evidence supporting the use of peer review in undergraduate science as a means to improve student writing and to alleviate barriers, such as lost class time, by incorporation of the peer-review process into the laboratory component of the course. The study was conducted in a single section of an undergraduate

  16. BIOCHEMISTRY AND MOLECULAR BIOLOGY

    E-print Network

    Wilson, Mark A.

    BIOCHEMISTRY AND MOLECULAR BIOLOGY CURRICULUM COMMITTEE: William Morgan (Biology), Chair Paul) Stephanie Strand (Biology) James West (Biochemistry and Molecular Biology) Crystal Young (Biochemistry and Molecular Biology) This interdisciplinary program, jointly administered by faculty from the Departments

  17. Synthesis and Kinetics of Hydrolysis of 3,5-Dimethyl-N-acetyl-p-benzoquinone Imine: An Undergraduate Laboratory

    NASA Astrophysics Data System (ADS)

    Buccigross, Jeanne M.; Metz, Christa; Elliot, Lori; Becker, Pamela; Earley, Angela S.; Hayes, Jerry W.; Novak, Michael; Underwood, Gayl A.

    1996-04-01

    The synthesis of the title compound by a three-step procedure is described. The hydrolysis kinetics, which involve two consecutive psuedo-first-order processes, are also described. The synthesis and kinetics experiments described here are proposed for incorporation into undergraduate laboratory courses under a variety of formats. The compound described here is related to a toxic metabolite of the common analgesics acetaminophen and phenacetin.

  18. Faculty perspectives of the undergraduate laboratory: A survey of faculty goals for the laboratory and comparative analysis of responses using statistical techniques

    NASA Astrophysics Data System (ADS)

    Bruck, Aaron D.

    Qualitative research methods were used in a previous study to discover the goals of faculty members teaching undergraduate laboratories. Assertions about the goals and the unique characteristics of innovative lab programs were developed from categories that emerged from the interviews. The purpose of the present research was to create a survey instrument to measure the prevalence of these themes and faculty goals for undergraduate laboratories with a national sample. This was achieved through a two-stage process that utilized a pilot survey to determine the factor structure and reduce the number of survey items to a manageable size. Once the number of survey questions was reduced, the full survey was given to a national sample of undergraduate laboratory faculty. The 312 responses to the survey were then analyzed using factor analysis. Comparative analyses were conducted using analysis of variance (ANOVA). This dissertation focuses on the processes involved in the creation of this survey and the subsequent analyses of the data the survey produced. The results of these analyses and the implications of this research will also be discussed.

  19. 75 FR 8147 - Notice of Consideration of Amendment Request for Decommissioning of Analytical Bio-Chemistry...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-23

    ...Amendment Request for Decommissioning of Analytical Bio-Chemistry Laboratories, Inc. Sanitary Lagoon, Columbia, Missouri...Material License No. 24- 13365-01 issued to Analytical Bio-Chemistry Laboratories, Inc. (the Licensee) pursuant to 10 CFR...

  20. Structured Inquiry-Based Learning: Drosophila GAL4 Enhancer Trap Characterization in an Undergraduate Laboratory Course

    PubMed Central

    Dunne, Christopher R.; Cillo, Anthony R.; Glick, Danielle R.; John, Katherine; Johnson, Cody; Kanwal, Jaspinder; Malik, Brian T.; Mammano, Kristina; Petrovic, Stefan; Pfister, William; Rascoe, Alexander S.; Schrom, Diane; Shapiro, Scott; Simkins, Jeffrey W.; Strauss, David; Talai, Rene; Tomtishen, John P.; Vargas, Josephine; Veloz, Tony; Vogler, Thomas O.; Clenshaw, Michael E.; Gordon-Hamm, Devin T.; Lee, Kathryn L.; Marin, Elizabeth C.

    2014-01-01

    We have developed and tested two linked but separable structured inquiry exercises using a set of Drosophila melanogaster GAL4 enhancer trap strains for an upper-level undergraduate laboratory methods course at Bucknell University. In the first, students learn to perform inverse PCR to identify the genomic location of the GAL4 insertion, using FlyBase to identify flanking sequences and the primary literature to synthesize current knowledge regarding the nearest gene. In the second, we cross each GAL4 strain to a UAS-CD8-GFP reporter strain, and students perform whole mount CNS dissection, immunohistochemistry, confocal imaging, and analysis of developmental expression patterns. We have found these exercises to be very effective in teaching the uses and limitations of PCR and antibody-based techniques as well as critical reading of the primary literature and scientific writing. Students appreciate the opportunity to apply what they learn by generating novel data of use to the wider research community. PMID:25549104

  1. Developing a new experimental system for an undergraduate laboratory exercise to teach theories of visuomotor learning.

    PubMed

    Kasuga, Shoko; Ushiba, Junichi

    2014-01-01

    Humans have a flexible motor ability to adapt their movements to changes in the internal/external environment. For example, using arm-reaching tasks, a number of studies experimentally showed that participants adapt to a novel visuomotor environment. These results helped develop computational models of motor learning implemented in the central nervous system. Despite the importance of such experimental paradigms for exploring the mechanisms of motor learning, because of the cost and preparation time, most students are unable to participate in such experiments. Therefore, in the current study, to help students better understand motor learning theories, we developed a simple finger-reaching experimental system using commonly used laptop PC components with an open-source programming language (Processing Motor Learning Toolkit: PMLT). We found that compared to a commercially available robotic arm-reaching device, our PMLT accomplished similar learning goals (difference in the error reduction between the devices, P = 0.10). In addition, consistent with previous reports from visuomotor learning studies, the participants showed after-effects indicating an adaptation of the motor learning system. The results suggest that PMLT can serve as a new experimental system for an undergraduate laboratory exercise of motor learning theories with minimal time and cost for instructors. PMID:25565915

  2. Testing plastic deformations of materials in the introductory undergraduate mechanics laboratory

    NASA Astrophysics Data System (ADS)

    Romo-Kröger, C. M.

    2012-05-01

    Normally, a mechanics laboratory at the undergraduate level includes an experiment to verify compliance with Hooke's law in materials, such as a steel spring and an elastic rubber band. Stress-strain curves are found for these elements. Compression in elastic bands is practically impossible to achieve due to flaccidity. A typical experiment for the complete loading-unloading cycle is to subject a tubular object to torsion. This paper suggests simple experiments for studying properties concerning elasticity and plasticity in elements of common use, subjected to stretching or compression, and also torsion reinforcing. The experiments use plastic binders, rubber bands and metal springs under a moderate load. This paper discusses an experiment with an original device to measure torsion deformations as a function of applied torques, which permitted construction of the hysteresis cycle for a rubber hose and various tubes. Another experiment was designed to define the temporal recovery of a plastic spring with initial stretching. A simple mathematical model was developed to explain this phenomenon.

  3. Developing a New Experimental System for an Undergraduate Laboratory Exercise to Teach Theories of Visuomotor Learning

    PubMed Central

    Kasuga, Shoko; Ushiba, Junichi

    2014-01-01

    Humans have a flexible motor ability to adapt their movements to changes in the internal/external environment. For example, using arm-reaching tasks, a number of studies experimentally showed that participants adapt to a novel visuomotor environment. These results helped develop computational models of motor learning implemented in the central nervous system. Despite the importance of such experimental paradigms for exploring the mechanisms of motor learning, because of the cost and preparation time, most students are unable to participate in such experiments. Therefore, in the current study, to help students better understand motor learning theories, we developed a simple finger-reaching experimental system using commonly used laptop PC components with an open-source programming language (Processing Motor Learning Toolkit: PMLT). We found that compared to a commercially available robotic arm-reaching device, our PMLT accomplished similar learning goals (difference in the error reduction between the devices, P = 0.10). In addition, consistent with previous reports from visuomotor learning studies, the participants showed after-effects indicating an adaptation of the motor learning system. The results suggest that PMLT can serve as a new experimental system for an undergraduate laboratory exercise of motor learning theories with minimal time and cost for instructors. PMID:25565915

  4. The Florida State University Department of Biological Science and The Florida State University Coastal & Marine Laboratory The Undergraduate Research Program in Marine Biology and Living Marine Resource Ecology is designed for

    E-print Network

    Bass, Hank W.

    Coastal & Marine Laboratory The Undergraduate Research Program in Marine Biology and Living Marine's potential for a career in marine biological research. Name of Reference THE UNDERGRADUATE RESEARCH PROGRAM IN MARINE BIOLOGY & LIVING MARINE RESOURCE ECOLOGY HTTP

  5. Demand for Interdisciplinary Laboratories for Physiology Research by Undergraduate Students in Biosciences and Biomedical Engineering

    ERIC Educational Resources Information Center

    Clase, Kari L.; Hein, Patrick W.; Pelaez, Nancy J.

    2008-01-01

    Physiology as a discipline is uniquely positioned to engage undergraduate students in interdisciplinary research in response to the 2006-2011 National Science Foundation Strategic Plan call for innovative transformational research, which emphasizes multidisciplinary projects. To prepare undergraduates for careers that cross disciplinary…

  6. Application of sigma metrics for the assessment of quality assurance in clinical biochemistry laboratory in India: a pilot study.

    PubMed

    Singh, Bhawna; Goswami, Binita; Gupta, Vinod Kumar; Chawla, Ranjna; Mallika, Venkatesan

    2011-04-01

    Ensuring quality of laboratory services is the need of the hour in the field of health care. Keeping in mind the revolution ushered by six sigma concept in corporate world, health care sector may reap the benefits of the same. Six sigma provides a general methodology to describe performance on sigma scale. We aimed to gauge our laboratory performance by sigma metrics. Internal quality control (QC) data was analyzed retrospectively over a period of 6 months from July 2009 to December 2009. Laboratory mean, standard deviation and coefficient of variation were calculated for all the parameters. Sigma was calculated for both the levels of internal QC. Satisfactory sigma values (>6) were elicited for creatinine, triglycerides, SGOT, CPK-Total and Amylase. Blood urea performed poorly on the sigma scale with sigma <3. The findings of our exercise emphasize the need for detailed evaluation and adoption of ameliorative measures in order to effectuate six sigma standards for all the analytical processes. PMID:22468038

  7. Effects of Various Dental Materials on Alkaline Phosphatase Extracted from Pulp: An Experiment for the Biochemistry Laboratory.

    ERIC Educational Resources Information Center

    Thompson, Lorin R.

    1980-01-01

    A laboratory experiment that demonstrates the effects of various dental materials on a representative enzyme from the pulp is outlined. The experiment encourages students to consider the effects that various restorative materials and techniques might have on enzymes in the living pulp. (Author/MLW)

  8. Quality of Undergraduate Physics Students' Written Scientific Arguments: How to Promote Students' Appropriation of Scientific Discourse in Physics Laboratory Reports?

    NASA Astrophysics Data System (ADS)

    Aydeniz, Mehmet; Yeter-Aydeniz, Kubra

    2015-03-01

    In this study we challenged 18 undergraduate physics students to develop four written scientific arguments across four physics labs: 1) gravity-driven acceleration, 2) conservation of mechanical energy, 3) conservation of linear momentum and 4) boyle's law, in a mechanics and thermodynamics laboratory course. We evaluated quality of the written scientific arguments developed by the participants using the Claim, Evidence, Reasoning and Rebuttal (CERR) rubric. The results indicate that while students developed adequate scientific explanations that summarized the findings of their experiments, they experienced unique difficulties in using a persuasive and critical discourse in their written arguments. Students experienced the most difficulty in considering alternative explanations in formulating their written scientific arguments. We elaborate on the implications of these findings for teaching physics laboratories and assessing students' learning in physics laboratories. We especially focus on the importance of framing in helping students to appropriate the epistemic norms of science in writing scientific arguments.

  9. Ion Exchange and Thin Layer Chromatographic Separation and Identification of Amino Acids in a Mixture: An Experiment for General Chemistry and Biotechnology Laboratories

    ERIC Educational Resources Information Center

    Brunauer, Linda S.; Caslavka, Katelyn E.; Van Groningen, Karinne

    2014-01-01

    A multiday laboratory exercise is described that is suitable for first-year undergraduate chemistry, biochemistry, or biotechnology students. Students gain experience in performing chromatographic separations of biomolecules, in both a column and thin layer chromatography (TLC) format. Students chromatographically separate amino acids (AA) in an…

  10. Determining the Transference Number of H[superscript +](aq) by a Modified Moving Boundary Method: A Directed Study for the Undergraduate Physical Chemistry Laboratory

    ERIC Educational Resources Information Center

    Dabke, Rajeev B.; Gebeyehu, Zewdu; Padelford, Jonathan

    2012-01-01

    A directed study for the undergraduate physical chemistry laboratory for determining the transference number of H[superscript +](aq) using a modified moving boundary method is presented. The laboratory study combines Faraday's laws of electrolysis with mole ratios and the perfect gas equation. The volume of hydrogen gas produced at the cathode is…

  11. Summer Undergraduate Research Opportunities in the Electric Propulsion and Plasmadynamics Laboratory (EPPDyL)*

    E-print Network

    Summer Undergraduate Research Opportunities in the Electric Propulsion and Plasmadynamics at jml@princeton.edu before April 11th for more information about funding opportunities. ADVANCED summer projects will vary based on experience. Advanced coursework and/or experience with electronic

  12. Analysis of Currently Available Analgesic Tablets by Modern Liquid Chromatography: An Undergraduate Laboratory Introduction to HPLC.

    ERIC Educational Resources Information Center

    Kagel, R. A.; Farwell, S. O.

    1983-01-01

    Background information, procedures, and results, are provided for an undergraduate experiment in which analgesic tablets are analyzed using liquid chromatography. The experiment, an improved, modified version of the Waters Associates Inc. experiment, is simple to prepare, requiring little glassware and minimal sample manipulation by students. (JN)

  13. Student Perceptions of an Upper-Level, Undergraduate Human Anatomy Laboratory Course without Cadavers

    ERIC Educational Resources Information Center

    Wright, Shirley J.

    2012-01-01

    Several programs in health professional education require or are considering requiring upper-level human anatomy as prerequisite for their applicants. Undergraduate students are confronted with few institutions offering such a course, in part because of the expense and logistical issues associated with a cadaver-based human anatomy course. This…

  14. Verification of Compton Collision and Klein-Nishina Formulas--An Undergraduate Laboratory Experiment

    ERIC Educational Resources Information Center

    Singhal, R. P.; Burns, A. J.

    1978-01-01

    Describes an experiment to verify the Compton collision formula and the angular dependance of the Klein-Nishina formula. Equipment used is a 1-mCi(137)Cs source, 2x2 in. NaI detector and a multichannel analyzer. Suitable for honor undergraduates. (Author/GA)

  15. A Cost-Effective Atomic Force Microscope for Undergraduate Control Laboratories

    ERIC Educational Resources Information Center

    Jones, C. N.; Goncalves, J.

    2010-01-01

    This paper presents a simple, cost-effective and robust atomic force microscope (AFM), which has been purposely designed and built for use as a teaching aid in undergraduate controls labs. The guiding design principle is to have all components be open and visible to the students, so the inner functioning of the microscope has been made clear to…

  16. Rapid Multistep Synthesis of a Bioactive Peptidomimetic Oligomer for the Undergraduate Laboratory

    ERIC Educational Resources Information Center

    Utku, Yeliz; Rohatgi, Abhinav; Yoo, Barney; Kirshenbaum, Kent; Zuckermann, Ronald N.; Pohl, Nicola L.

    2010-01-01

    Peptidomimetic compounds are increasingly important in drug-discovery applications. We introduce the synthesis of an N-substituted glycine oligomer, a bioactive "peptoid" trimer. The six-step protocol is conducted on solid-phase resin, enabling the synthesis to be performed by undergraduate organic chemistry students. This synthesis lab was…

  17. Physico-Geometrical Kinetics of Solid-State Reactions in an Undergraduate Thermal Analysis Laboratory

    ERIC Educational Resources Information Center

    Koga, Nobuyoshi; Goshi, Yuri; Yoshikawa, Masahiro; Tatsuoka, Tomoyuki

    2014-01-01

    An undergraduate kinetic experiment of the thermal decomposition of solids by microscopic observation and thermal analysis was developed by investigating a suitable reaction, applicable techniques of thermal analysis and microscopic observation, and a reliable kinetic calculation method. The thermal decomposition of sodium hydrogen carbonate is…

  18. Teaching Raman Spectroscopy in Both the Undergraduate Classroom and the Laboratory with a Portable Raman Instrument

    Microsoft Academic Search

    Evan D. Hudspeth; Danielle Cleveland; Kathleen L. Batchler; Phuong A. Nguyen; Tracey L. Feaser; Lauren E. Quattrochi; Jesse Morenz; Shrimati A. Balram; Robert G. Michel; Jack Zhou; Daniel Lombardi

    2006-01-01

    We have evaluated a small portable Raman instrument on loan from B&W Tek, Inc., and have determined that it can successfully be used in the classroom both as a visual aid for teaching the fundamentals of Raman spectroscopy and for a variety of undergraduate experiments as a normal component of an instrumental analysis class. Having portable Raman instrumentation would allow

  19. Automated scanning probe lithography with n-alkanethiol self assembled monolayers on Au(111): Application for teaching undergraduate laboratories

    PubMed Central

    Brown, Treva T.; LeJeune, Zorabel M.; Liu, Kai; Hardin, Sean; Li, Jie-Ren; Rupnik, Kresimir; Garno, Jayne C.

    2010-01-01

    Controllers for scanning probe instruments can be programmed for automated lithography to generate desired surface arrangements of nanopatterns of organic thin films, such as n-alkanethiol self-assembled monolayers (SAMs). In this report, atomic force microscopy (AFM) methods of lithography known as nanoshaving and nanografting are used to write nanopatterns within organic thin films. Commercial instruments provide software to control the length, direction, speed, and applied force of the scanning motion of the tip. For nanoshaving, higher forces are applied to an AFM tip to selectively remove regions of the matrix monolayer, exposing bare areas of the gold substrate. Nanografting is accomplished by force-induced displacement of molecules of a matrix SAM, followed immediately by the surface self-assembly of n-alkanethiol molecules from solution. Advancements in AFM automation enable rapid protocols for nanolithography, which can be accomplished within the tight time restraints of undergraduate laboratories. Example experiments with scanning probe lithography (SPL) will be described in this report that were accomplished by undergraduate students during laboratory course activities and research internships in the chemistry department of Louisiana State University. Students were introduced to principles of surface analysis and gained “hands-on” experience with nanoscale chemistry. PMID:21483651

  20. Automated scanning probe lithography with n-alkanethiol self-assembled monolayers on Au(111): application for teaching undergraduate laboratories.

    PubMed

    Brown, Treva T; LeJeune, Zorabel M; Liu, Kai; Hardin, Sean; Li, Jie-Ren; Rupnik, Kresimir; Garno, Jayne C

    2011-04-01

    Controllers for scanning probe instruments can be programmed for automated lithography to generate desired surface arrangements of nanopatterns of organic thin films, such as n-alkanethiol self-assembled monolayers (SAMs). In this report, atomic force microscopy (AFM) methods of lithography known as nanoshaving and nanografting are used to write nanopatterns within organic thin films. Commercial instruments provide software to control the length, direction, speed, and applied force of the scanning motion of the tip. For nanoshaving, higher forces are applied to an AFM tip to selectively remove regions of the matrix monolayer, exposing bare areas of the gold substrate. Nanografting is accomplished by force-induced displacement of molecules of a matrix SAM, followed immediately by the surface self-assembly of n-alkanethiol molecules from solution. Advancements in AFM automation enable rapid protocols for nanolithography, which can be accomplished within the tight time restraints of undergraduate laboratories. Example experiments with scanning probe lithography will be described in this report that were accomplished by undergraduate students during laboratory course activities and research internships in the chemistry department of Louisiana State University. Students were introduced to principles of surface analysis and gained "hands-on" experience with nanoscale chemistry. PMID:21609692

  1. Automated scanning probe lithography with n-alkanethiol self assembled monolayers on Au(111): Application for teaching undergraduate laboratories.

    PubMed

    Brown, Treva T; Lejeune, Zorabel M; Liu, Kai; Hardin, Sean; Li, Jie-Ren; Rupnik, Kresimir; Garno, Jayne C

    2011-04-01

    Controllers for scanning probe instruments can be programmed for automated lithography to generate desired surface arrangements of nanopatterns of organic thin films, such as n-alkanethiol self-assembled monolayers (SAMs). In this report, atomic force microscopy (AFM) methods of lithography known as nanoshaving and nanografting are used to write nanopatterns within organic thin films. Commercial instruments provide software to control the length, direction, speed, and applied force of the scanning motion of the tip. For nanoshaving, higher forces are applied to an AFM tip to selectively remove regions of the matrix monolayer, exposing bare areas of the gold substrate. Nanografting is accomplished by force-induced displacement of molecules of a matrix SAM, followed immediately by the surface self-assembly of n-alkanethiol molecules from solution. Advancements in AFM automation enable rapid protocols for nanolithography, which can be accomplished within the tight time restraints of undergraduate laboratories. Example experiments with scanning probe lithography (SPL) will be described in this report that were accomplished by undergraduate students during laboratory course activities and research internships in the chemistry department of Louisiana State University. Students were introduced to principles of surface analysis and gained "hands-on" experience with nanoscale chemistry. PMID:21483651

  2. Preparation, Purification, and Secondary Structure Determination of Bacillus Circulans Xylanase. A Molecular Laboratory Incorporating Aspects of Molecular Biology, Biochemistry, and Biophysical Chemistry

    ERIC Educational Resources Information Center

    Russo, Sal; Gentile, Lisa

    2006-01-01

    A project module designed for biochemistry or cellular and molecular biology student which involves determining the secondary structure of Bacillus circulans xylanase (BCX) by circular dichroism (CD) spectroscopy under conditions that compromise its stabilizing intramolecular forces is described. The lab model enhanced students knowledge of the…

  3. A Simplified Undergraduate Laboratory Experiment to Evaluate the Effect of the Ionic Strength on the Equilibrium Concentration Quotient of the Bromcresol Green Dye

    ERIC Educational Resources Information Center

    Rodriguez, Hernan B.; Mirenda, Martin

    2012-01-01

    A modified laboratory experiment for undergraduate students is presented to evaluate the effects of the ionic strength, "I", on the equilibrium concentration quotient, K[subscript c], of the acid-base indicator bromcresol green (BCG). The two-step deprotonation of the acidic form of the dye (sultone form), as it is dissolved in water, yields…

  4. Using Mole Ratios of Electrolytic Products of Water for Analysis of Household Vinegar: An Experiment for the Undergraduate Physical Chemistry Laboratory

    ERIC Educational Resources Information Center

    Dabke, Rajeev B.; Gebeyehu, Zewdu

    2012-01-01

    A simple 3-h physical chemistry undergraduate experiment for the quantitative analysis of acetic acid in household vinegar is presented. The laboratory experiment combines titration concept with electrolysis and an application of the gas laws. A vinegar sample was placed in the cathode compartment of the electrolysis cell. Electrolysis of water…

  5. Synthesis and Characterization of Aldol Condensation Products from Unknown Aldehydes and Ketones: An Inquiry-Based Experiment in the Undergraduate Laboratory

    ERIC Educational Resources Information Center

    Angelo, Nicholas G.; Henchey, Laura K.; Waxman, Adam J.; Canary, James W.; Arora, Paramjit S.; Wink, Donald

    2007-01-01

    An experiment for the undergraduate chemistry laboratory in which students perform the aldol condensation on an unknown aldehyde and an unknown ketone is described. The experiment involves the use of techniques such as TLC, column chromatography, and recrystallization, and compounds are characterized by [to the first power]H NMR, GC-MS, and FTIR.…

  6. Virtual and Traditional Slides for Teaching Cellular Morphology to Medical Laboratory Science Undergraduates: A Comparative Study of Performance Outcomes, Retention, and Self-Efficacy Beliefs

    ERIC Educational Resources Information Center

    Solberg, Brooke L.

    2011-01-01

    As a result of massive retirement and educational program expense and closure, the field of Medical Laboratory Science (MLS) is facing a critical workforce shortage. Combatting this issue by increasing undergraduate class size is a difficult proposition due to the intense psychomotor curricular requirements of MLS programs. Technological advances…

  7. A Western Blot-based Investigation of the Yeast Secretory Pathway Designed for an Intermediate-Level Undergraduate Cell Biology Laboratory

    ERIC Educational Resources Information Center

    Hood-DeGrenier, Jennifer K.

    2008-01-01

    The movement of newly synthesized proteins through the endomembrane system of eukaryotic cells, often referred to generally as the secretory pathway, is a topic covered in most intermediate-level undergraduate cell biology courses. An article previously published in this journal described a laboratory exercise in which yeast mutants defective in…

  8. Impact of Backwards Faded Scaffolding Approach to Inquiry-Based Astronomy Laboratory Experiences on Undergraduate Non-Science Majors' Views of Scientific Inquiry

    ERIC Educational Resources Information Center

    Lyons, Daniel J.

    2011-01-01

    This study explored the impact of a novel inquiry-based astronomy laboratory curriculum designed using the Backwards Faded Scaffolding inquiry teaching framework on non-science majoring undergraduate students' views of the nature of scientific inquiry (NOSI). The study focused on two aspects of NOSI: The Distinction between Data and Evidence…

  9. Photoemission energy distribution measurements in a simple metal: A modern physics undergraduate laboratory

    NASA Astrophysics Data System (ADS)

    Zangara, Rosalia; Lanzara, Elisa

    1993-12-01

    Measurement of energy distribution curves (EDCs) is one of the more powerful techniques for investigating the electronic band structure of solids. It would be profitable for undergraduate students to perform an experiment introducing them to this aspect of modern spectroscopy. In this paper we describe an arrangement we use in our course of modern physics for engineering students utilizing a commercial photocell. After a theoretical background on the photoemission process in metal, we present measurements on the EDCs obtained by graphical differentiation of the I-V characteristics of the photocell and by using an ac method where the differentiation is performed electronically.

  10. Peer Assessment in Large Undergraduate Classes: An Evaluation of a Procedure for Marking Laboratory Reports and a Review of Related Practices

    NSDL National Science Digital Library

    2011-06-01

    This study provides evidence that peer marking can be a reliable tool for assessing laboratory reports in large cohorts. It was conducted over a 4-yr period with first-year undergraduates taking a mammalian physiology course, but the procedure adopted would be applicable to any other laboratory-based discipline. The process was found to be efficient in staff time, enabling a summative practical report to be marked in <1 h, facilitating rapid feedback to students on their performance.

  11. Parallel Combinatorial Synthesis of Azo Dyes: A Combinatorial Experiment Suitable for Undergraduate Laboratories

    ERIC Educational Resources Information Center

    Gung, Benjamin W.; Taylor, Richard T.

    2004-01-01

    An experiment in the parallel synthesis of azo dyes that demonstrates the concepts of structure-activity relationships and chemical diversity with vivid colors is described. It is seen that this experiment is suitable for the second-semester organic chemistry laboratory and also for the one-semester organic laboratory.

  12. Research and Teaching: Characterizing the Level of Inquiry in the Undergraduate Laboratory

    NSDL National Science Digital Library

    Laura B. Bruck

    2008-09-01

    Discrepancies abound in use of the word "inquiry." In this paper, the authors propose a quantitative rubric designed to characterize the level of inquiry in laboratory activities and laboratory curricula. They do not wish to answer the question, "What is inquiry?" but rather, provide a tool for identifying its varying degrees of student independence.

  13. Using a Logic Model to Evaluate Undergraduate Instruction in a Laboratory Preschool

    ERIC Educational Resources Information Center

    Monroe, Lisa; Horm, Diane M.

    2012-01-01

    Research Findings: Utilization-focused, process evaluations of university-based laboratory preschools in their role with teacher preparation programs are rare in the current literature. This paper describes a self-study evaluation designed and implemented at a university laboratory preschool. A theory approach logic model was developed and used to…

  14. Successful implementation of inquiry-based physiology laboratories in undergraduate major and nonmajor courses

    NSDL National Science Digital Library

    G Casotti (West Chester University of Pennsylvania Biology)

    2008-12-01

    Recent evidence has demonstrated that inquiry-based physiology laboratories improve students' critical- and analytical-thinking skills. We implemented inquiry-based learning into three physiology courses: Comparative Vertebrate Physiology (majors), Human Physiology (majors), and Human Anatomy and Physiology (nonmajors). The aims of our curricular modifications were to improve the teaching of physiological concepts, teach students the scientific approach, and promote creative and critical thinking. We assessed our modifications using formative (laboratory exams, oral presentations, and laboratory reports) and summative evaluations (surveys, laboratory notebook, and an end of semester project). Students appreciated the freedom offered by the new curriculum and the opportunity to engage in the inquiry process. Results from both forms of evaluation showed a marked improvement due to the curricular revisions. Our analyses indicate an increased confidence in students' ability to formulate questions and hypotheses, design experiments, collect and analyze data, and make conclusions. Thus, we have successfully incorporated inquiry-based laboratories in both major and nonmajor courses.

  15. Molecular Models for Biochemistry

    NSDL National Science Digital Library

    This Carnegie Mellon University website uses Chime and RasMol images to provide students with many biochemistry tutorials and quizzes. Intended as a supplement to a standard biochemistry text, users can find numerous 3-D images of small molecules, amino acids, protein structures, and much more. The website offers extensive viewing suggestions and tutorials on Chime and RasMol. With countless interactive materials and quizzes, biochemistry students can find the help they need at this extraordinary website.

  16. qPCR for second year undergraduates: A short, structured inquiry to illustrate differential gene expression.

    PubMed

    McCauslin, Christine Seitz; Gunn, Kathryn Elaine; Pirone, Dana; Staiger, Jennifer

    2015-07-01

    We describe a structured inquiry laboratory exercise that examines transcriptional regulation of the NOS2 gene under conditions that simulate the inflammatory response in macrophages. Using quantitative PCR and the comparative CT method, students are able determine whether transcriptional activation of NOS2 occurs and to what degree. The exercise is aimed at second year undergraduates who possess basic knowledge of gene expression events. It requires only 4-5 hr of dedicated laboratory time and focuses on use of the primary literature, data analysis, and interpretation. Importantly, this exercise provides a mechanism to introduce the concept of differential gene expression and provides a starting point for development of more complex guided or open inquiry projects for students moving into upper level molecular biology, immunology, and biochemistry course work. © 2015 by the International Union of Biochemistry and Molecular Biology, 43(4):273-282, 2015. PMID:26148025

  17. Design, Implementation, and Assessment of an Undergraduate Interdisciplinary Watershed Research Laboratory

    NSDL National Science Digital Library

    Christopher Woltemade

    2002-09-01

    This article discusses the establishment of Shippensburg University's Burd Run Interdisciplinary Watershed Research Laboratory and the advantages of linking disciplinary perspectives across courses in geology, geography, biology, and teacher education. The laboratory provides an easily adaptable conceptual model for improving environmental science education at teaching-oriented institutions nationwide. Its success is largely attributable to three factors: the project is student-centered and goal specific; the selected watershed is accessible, diverse, and at a manageable scale; and the Laboratory Advisory Board provides for continuous revision, adaptation, and improvement.

  18. Undergraduates at Sea and in the Laboratory Conducting Habitat Mapping Using Multibeam and Sidescan Sonar

    NASA Astrophysics Data System (ADS)

    Sautter, L. R.; Harris, M. S.

    2008-12-01

    During the last five years, undergraduate students at the College of Charleston have had numerous opportunities to take part in the college's Transect Program and sail aboard research vessels on 2-5 day cruises to study the continental shelf. The program's purpose is to train students in oceanographic research while developing a long-term information geodatabase to characterize and monitor essential fish habitats, and to map seafloor geomorphology. During these cruises students take the lead to conduct a variety of research investigations which include hydrographic surveys of the seafloor using sidescan sonar, multibeam bathymetry, and video collected using a remotely operated vehicle and during SCUBA dives. Following the data collection cruises, students have enrolled in semester-long research courses to analyze data and document results through poster and oral presentations. More than 60 students have taken part in at least one of 6 programs. In the past two years, the NOAA Ship NANCY FOSTER has provided invaluable sea time to conduct multibeam surveys of the mid- and outer continental shelf off Charleston, so that the 22 participating Transect students have focused their work on seafloor mapping, and have become trained in state-of-the art CARIS multibeam and sidescan sonar processing software. Most of these students have presented their results at professional meetings, and manuscripts are currently in preparation. Students have had numerous post-program opportunities to conduct further research at sea and in the lab. They have collaborated with NOAA scientists and other investigators, conducting bathymetry data processing and analysis from other regions. Most recently, two program graduates worked with University of Washington investigators to map sites for the Ocean Observatory Initiative Regional Scale Nodes. Several students have been contracted or hired as hydrographic survey technicians, while others have gone to graduate school to continue their work using these invaluable skills learned as undergraduates.

  19. Laboratory exercises incorporating a Scanning Electron Microscope (SEM) encourage undergraduate students to

    E-print Network

    Beane, Rachel J.

    ABSTRACT Laboratory exercises incorporating a Scanning Electron Microscope (SEM) encourage-pressure scanning electron microscopes (SEM) that can be equipped with an energy-dispersive spectrometer (EDS Energy Dispersive Spectrometer (EDS) and Electron Backscatter Diffractometer (EBSD), has been used

  20. The scanning electron microscope as an accelerator for the undergraduate advanced physics laboratory

    E-print Network

    Peterson, Randolph S.

    Few universities or colleges have an accelerator for use with advanced physics laboratories, but many of these institutions have a scanning electron microscope (SEM) on site, often in the biology department. As an accelerator ...

  1. Gamma-Nonanoic Lactone: Synthesis of a Fragrance and Flavor Enhancer in the Undergraduate Laboratory.

    ERIC Educational Resources Information Center

    Bunce, Richard A.; Reeves, Henry D.

    1990-01-01

    Described is an experiment in which students are able to synthesize an unnatural compound having the odor and flavor of coconuts. Laboratory equipment, procedures, and analysis of the product are discussed. (CW)

  2. An investigation of student understanding in the undergraduate organic chemistry laboratory

    NASA Astrophysics Data System (ADS)

    Grutsch, John Leo, Jr.

    Laboratory activities in organic chemistry involve a mixture of sophisticated logic and empirical observation that requires the integration of mechanistic thought, laboratory technique, and problem-solving skills. In an effort to understand how students develop the thought processes and problem-solving skills necessary for laboratory work in organic chemistry, student understanding of how the interaction between a reaction system (reactants or starting material(s), reagent(s), and/or solvent), experimental variables (pH, temperature, concentrations, etc), provides a result of interest (yield, selectivity, purity, etc.) for an experiment performed in the organic chemistry laboratory was investigated through the collection of responses to questions posed on pre-laboratory quizzes followed by in-depth interviews during which student volunteers discussed their responses along with their experiences in the laboratory. The conceptual change theory of learning which assumes new conceptions are understood, judged, acquired, or rejected in a conceptual context was used as a theoretical paradigm to examine students responses to questions posed on pre-laboratory quizzes and transcripts of the interviews with student volunteers. Students were found to not have developed a mechanistic understanding of how the interaction between a reaction system (reactants or starting material(s), reagent(s), and/or solvent), experimental variables (pH, temperature, concentrations, etc), provides a result of interest (yield, selectivity, purity, etc.) for an experiment performed in the organic chemistry laboratory. However, students' prior exposure to and understanding of chemical concepts was found to simultaneously assist and hinder in their development of a partial mechanistic understanding of how a reaction system (reactants or starting material(s), reagent(s), and/or solvent), experimental variables (pH, temperature, concentrations, etc), interact to provide a result of interest (yield, selectivity, purity, etc.). Even though students were able to develop a partial mechanistic understanding, they still did not understand the rationale behind chemical or physical manipulation performed in the organic chemistry laboratory or how either may be applied to other experiments. Therefore, experiments performed in the organic chemistry laboratory became activities in which students gave little thought to what they were doing resulting in little meaningful learning, unsafe practices, and an unpleasant experience that demotivated students. To address this deficiency, instructors need to create an environment where students are allowed to develop an understanding of the role of reagents and reaction conditions in an experiment in order to acquire the knowledge and skills that permits them to develop a deep mechanistic understanding of how organic chemistry reactions are implemented in the organic chemistry laboratory.

  3. Using Assessment to Improve Learning in the Biochemistry Classroom

    ERIC Educational Resources Information Center

    Loertscher, Jennifer

    2010-01-01

    In recent years, major drivers of undergraduate science education reform including the National Science Foundation (NSF) and the Howard Hughes Medical Institute (HHMI) have called on college and university instructors to take a more scientific approach to their teaching. Although many biochemistry instructors are gaining confidence in using…

  4. DEPARTMENT OF CHEMISTRY & BIOCHEMISTRY COLLEGE OF NATURAL SCIENCES AND MATHEMATICS

    E-print Network

    Heaton, Thomas H.

    DEPARTMENT OF CHEMISTRY & BIOCHEMISTRY COLLEGE OF NATURAL SCIENCES AND MATHEMATICS BIO-ORGANIC at the Assistant Professor level with expertise in BIO-ORGANIC CHEMISTRY. Position The successful candidates undergraduate and graduate students in organic chemistry with a preference for bioorganic chemistry, natural

  5. A laboratory module on radiometry, photometry and colorimetry for an undergraduate optics course

    NASA Astrophysics Data System (ADS)

    Polak, Robert D.

    2014-07-01

    The bachelor's degree in Physics at Loyola University Chicago requires both an upper-division course in Optics as well as a companion Optics Laboratory course. Recently, the laboratory course has undergone dramatic changes. Traditional weekly laboratories have been replaced with three laboratory modules, where students focus on a single topic over several weeks after which the students submit a laboratory report written in the style of a journal article following American Institute of Physics style manual. With this method, students are able to gain a deeper understanding of the specific topic areas of radiometry, photometry and colorimetry, lens design and aberrations, and polarization and interference while using industry-standard equipment and simulation software. In particular, this work will provide the details of the laboratory module on radiometry, photometry and colorimetry where students use a photoradiometer and integrating sphere to characterize the optical properties of an LCD monitor, light bulb and a fiber optic light source calculating properties such as luminous flux, luminous intensity, luminance, CIE color coordinates, NTSC ratio, color temperature and luminous efficacy.

  6. An undergraduate laboratory exercise to study the effect of darkness on plant gene expression using DNA microarray.

    PubMed

    Chang, Ming-Mei; Briggs, George M

    2007-11-01

    DNA microarrays are microscopic arrays on a solid surface, typically a glass slide, on which DNA oligonucleotides are deposited or synthesized in a high-density matrix with a predetermined spatial order. Several types of DNA microarrays have been developed and used for various biological studies. Here, we developed an undergraduate laboratory exercise using an Arabidopsis DNA microarray to study the gene expression of Brassica rapa, Wisconsin Fast Plant. Genes involved in senescence, cell wall loosening/degradation, and sugar transport were the most upregulated, while those involved in photosynthesis, the elimination of reactive oxygen intermediates associated with photooxidative stress and auxin synthesis, were the most downregulated. Students were able to complete the experiment successfully. Throughout the exercise, they learned various important molecular techniques including RNA isolation, quantification, reverse transcription, cRNA synthesis, labeling and purification, and microarray hybridization, washing, scanning, and feature extraction. The exercise can be integrated into a college-level molecular biology laboratory. The procedure used can be adapted to examine other effects on other organisms. PMID:21591140

  7. Curricular Guidelines in Biochemistry.

    ERIC Educational Resources Information Center

    Adams, A. Birk; And Others

    1981-01-01

    Curricular guidelines for biochemistry are presented, developed by the Section on Biochemistry and Nutrition and the Section on Oral Diagnosis and Oral Medicine of the American Association of Dental Schools for use by individual educational institutions as curriculum development aids. (MLW)

  8. Partnership in Undergraduate Research Experience

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Practical laboratory and work experience has been helpful in reinforcing the undergraduate educational experience. With limited resources, individual organizations may struggle to give a student a well rounded opportunity. Most undergraduates work within internships or cooperative educational fram...

  9. Characterizing Mystery Cell Lines: Student-driven Research Projects in an Undergraduate Neuroscience Laboratory Course

    PubMed Central

    Lemons, Michele L.

    2012-01-01

    Inquiry-based projects promote discovery and retention of key concepts, increase student engagement, and stimulate interest in research. Described here are a series of lab exercises within an undergraduate upper level neuroscience course that train students to design, execute and analyze their own hypothesis-driven research project. Prior to developing their own projects, students learn several research techniques including aseptic cell culture, cell line maintenance, immunocytochemistry and fluorescent microscopy. Working in groups, students choose how to use these techniques to characterize and identify a “mystery” cell line. Each lab group is given a unique cell line with either a neural, astrocyte, or Schwann cell origin. Working together, students plan and execute experiments to determine the cellular origin and other unique characteristics of their mystery cell line. Students generate testable hypotheses, design interpretable experiments, generate and analyze data, and report their findings in both oral and written formats. Students receive instructor and peer feedback throughout the entire project. In summary, these labs train students the process of scientific research. This series of lab exercises received very strong positive feedback from the students. Reflections on student feedback and plans for future improvements are discussed. PMID:23504583

  10. Studying Epigenetic DNA Modifications in Undergraduate Laboratories Using Complementary Bioinformatic and Molecular Approaches

    ERIC Educational Resources Information Center

    Militello, Kevin T.

    2013-01-01

    Epigenetic inheritance is the inheritance of genetic information that is not based on DNA sequence alone. One type of epigenetic information that has come to the forefront in the last few years is modified DNA bases. The most common modified DNA base in nature is 5-methylcytosine. Herein, we describe a laboratory experiment that combines…

  11. Microfluidics Meets Dilute Solution Viscometry: An Undergraduate Laboratory to Determine Polymer Molecular Weight Using a Microviscometer

    ERIC Educational Resources Information Center

    Pety, Stephen J.; Lu, Hang; Thio, Yonathan S.

    2011-01-01

    This paper describes a student laboratory experiment to determine the molecular weight of a polymer sample by measuring the viscosity of dilute polymer solutions in a PDMS microfluidic viscometer. Sample data are given for aqueous solutions of poly(ethylene oxide) (PEO). A demonstration of shear thinning behavior using the microviscometer is…

  12. Solid-Liquid and Liquid-Liquid Mixing Laboratory for Chemical Engineering Undergraduates

    ERIC Educational Resources Information Center

    Pour, Sanaz Barar; Norca, Gregory Benoit; Fradette, Louis; Legros, Robert; Tanguy, Philippe A.

    2007-01-01

    Solid-liquid and liquid-liquid mixing experiments have been developed to provide students with a practical experience on suspension and emulsification processes. The laboratory focuses on the characterization of the process efficiency, specifically the influence of the main operating parameters and the effect of the impeller type. (Contains 2…

  13. Reflective Practice: A Place in Enhancing Learning in the Undergraduate Bioscience Teaching Laboratory?

    ERIC Educational Resources Information Center

    Parry, Damian; Walsh, Cathy; Larsen, Carl; Hogan, Joanne

    2012-01-01

    Bioscience employers demand graduates with better practical competence. It is our supposition that, although undesirable, student learning is assessment driven and this is leading students to simply go through the motions in the practical setting (whether field work or laboratory based). In this intervention a Critical Incident Report was…

  14. Detection of Psilocybin Mushroom Analogs in Chocolate: Incorporating Current Events into the Undergraduate Teaching Laboratory

    Microsoft Academic Search

    Brandon Huskins; Christopher R. Dockery

    2009-01-01

    In this experiment, tryptamine is used as a psilocin analog and is dispersed onto a Fisher brand cellulose laboratory sponge to simulate dehydrated mushrooms. The resulting “mushroom” material is ground, molded into chocolate, and presented to student groups for real-world and applied analyses. Students isolate the tryptamine from the chocolate using their knowledge of drug chemistry, solubility, pH, extractions, etc.

  15. A Hands-on Laboratory based Approach to Undergraduate Robotics Education

    Microsoft Academic Search

    Kuldeep S. Rawat; Gholam H. Massiha

    2004-01-01

    The paper describes the teaching experience gathered along four years, including the choices of robotics platform, simulator, typical experiments and projects we have conducted for students. We also discuss our efforts and plans to develop a hands-on laboratory course for the education in Robotics and Automation. The course is designed to the multidisciplinary and can be offered for engineering and

  16. The effectiveness and user perception of 3-dimensional digital human anatomy in an online undergraduate anatomy laboratory

    NASA Astrophysics Data System (ADS)

    Hilbelink, Amy Joanne

    2007-12-01

    The primary purpose of this study was to determine the effectiveness of implementing desktop 3-dimensional (3D) stereo images of human anatomy into an undergraduate human anatomy distance laboratory. User perceptions of 2D and 3D images were gathered via questionnaire in order to determine ease of use and level of satisfaction associated with the 3D software in the online learning environment. Mayer's (2001, p. 184) principles of design were used to develop the study materials that consisted of PowerPoint presentations and AVI files accessed via Blackboard. The research design employed a mixed-methods approach. Volunteers each were administered a demographic survey and were then stratified into groups based upon pre-test scores. A total sample size of 62 pairs was available for combined data analysis. Quantitative research questions regarding the effectiveness of 2D versus the 3D treatment were analyzed using a doubly-multivariate repeated measures (Doubly-MANOVA) design. Paired test scores achieved by undergraduates on a laboratory practical of identification and spatial relationships of the bones and features of a human skull were used in the analysis. The questionnaire designed to gather user perceptions consisted of quantitative and qualitative questions. Response frequencies were analyzed for the two groups and common themes were noted. Results revealed a statistically significant difference in group means for the main effect of the treatment groups 2D and 3D and for the variables of identification and relationship with the 3D group outperforming the 2D group on both dependent variables. Effect sizes were determined to be small, 0.215 for the identification variable and 0.359 for the relationship variable. Overall, all students liked the convenience of using PowerPoint and AVI files online. The 3D group felt their PowerPoint was more realistic than did the 2D group and both groups appreciated the detailed labeling of the online images. One third of the volunteers in the 3D group indicated that "eye strain" was what they liked least about working with the 3D images. Results indicate that desktop, stereo imaging may be incorporated effectively into online anatomy and physiology courses, but that more work needs to be done to ensure less eye strain.

  17. Bringing the Excitement and Motivation of Research to Students; Using Inquiry and Research-Based Learning in a Year-Long Biochemistry Laboratory: Part I--Guided Inquiry--Purification and Characterization of a Fusion Protein--Histidine Tag, Malate Dehydrogenase, and Green Fluorescent Protein

    ERIC Educational Resources Information Center

    Knutson, Kristopher; Smith, Jennifer; Wallert, Mark A.; Provost, Joseph J.

    2010-01-01

    A successful laboratory experience provides the foundation for student success, creating active participation in the learning process. Here, we describe a new approach that emphasizes research, inquiry and problem solving in a year-long biochemistry experience. The first semester centers on the purification, characterization, and analysis of a…

  18. Use of the Herb Gymnema sylvestre to Illustrate the Principles of Gustatory Sensation: An Undergraduate Neuroscience Laboratory Exercise

    PubMed Central

    Schroeder, Joseph A.; Flannery-Schroeder, Ellen

    2005-01-01

    The Indian herb Gymnema sylvestre has been used in traditional Ayurvedic medicine for 2000 years, most recently for the treatment of diabetes. Loose leaf Gymnema sylvestre can be prepared as a tea and will impair the ability to taste sugar by blocking sweet receptors on the tongue. This report describes a laboratory exercise easily applied to an undergraduate neuroscience course that can be used to illustrate the principles of gustatory sensation. Combined with a preceding lecture on the primary taste sensations, students experience and appreciate how the primary tastes are combined to produce overall taste. In addition, the exercises outlined here expand upon previously published demonstrations employing Gymnema sylvestre to include illustrations of the different sensory transduction mechanisms associated with each of the four or five primary taste modalities. Students compare their qualitative primary taste experiences to salt, sugar, aspartame, chocolate, and sweet-sour candy prior to and following exposure to Gymnema sylvestre. The herb’s impairment of sweet sensation is profound and dramatically alters the perception of sweetness in sugar, chocolate, and candy without altering the perception of the other primary tastes. The exercise has an indelible effect on students because the herb’s intense effect compels students to rely on their unique personal experiences to highlight the principles of gustatory sensation. PMID:23493970

  19. BOREAS TE-9 NSA Canopy Biochemistry

    NASA Technical Reports Server (NTRS)

    Hall, Forrest G. (Editor); Curd, Shelaine (Editor); Margolis, Hank; Charest, Martin; Sy, Mikailou

    2000-01-01

    The BOREAS TE-9 team collected several data sets related to chemical and photosynthetic properties of leaves. This data set contains canopy biochemistry data collected in 1994 in the NSA at the YJP, OJR, OBS, UBS, and OA sites, including biochemistry lignin, nitrogen, cellulose, starch, and fiber concentrations. These data were collected to study the spatial and temporal changes in the canopy biochemistry of boreal forest cover types and how a high-resolution radiative transfer model in the mid-infrared could be applied in an effort to obtain better estimates of canopy biochemical properties using remote sensing. The data are available in tabular ASCII files. The data files are available on a CD-ROM (see document number 20010000884), or from the Oak Ridge National Laboratory (ORNL) Distributed Active Archive Center (DAAC).

  20. Tackling diversity challenges in Geoscience with the "Advancing Space Science Undergraduate Research Experience" (ASSURE) program at UC Berkeley's Space Sciences Laboratory.

    NASA Astrophysics Data System (ADS)

    Raftery, C. L.; Paglierani, R.; Shackelford, R. L., III; Peticolas, L. M.; Frappier, R.; Mendez, B.

    2014-12-01

    The Space Sciences Laboratory (SSL) has a long history of undergraduates working within the various research groups that range from theoretical astrophysics through to mechanical engineering. This year, we have established for the first time, a formal summer program for the undergraduate students, focusing on students traditionally underserved in Geosciences. This program, called the Advancing Space Science through Undergraduate Research Experiences program brings best-practiced methods to the development of a cohort, academic achievement, and research methodologies to the summer interns, with emphasis on the needs of underrepresented students who have not been exposed to a research environment before. In addition, specific care was given when recruiting for the program. Community College students recommend to us by faculty partners within the Colleges were recruited in order to provide them with hands on experience in a laboratory setting that they would not otherwise have had. In addition, we selected a number of pre- and in-service teachers from the STEM Teacher and Researcher Program (STAR) program. The combination of these two demographics of students has provided a unique and supportive environment for all involved.

  1. MBiochem (Single Honours Degree) Biochemistry

    E-print Network

    Brierley, Andrew

    ) Biology and Economics Biology and Geography Biology and Geology Biology and Logic and Philosophy58 Biology MBiochem (Single Honours Degree) Biochemistry BSc (Single Honours Degrees) Behavioural Biology Biochemistry Biology Biomolecular Science (offered by the School of Chemistry, includes some

  2. Initial Design and Development of an Integrated Laboratory Network: A New Approach for the Use of Instrumentation in the Undergraduate Curriculum

    NASA Astrophysics Data System (ADS)

    Cancilla, Devon A.

    2004-12-01

    This paper describes both the conceptual framework and initial development of Western Washington University's Integrated Laboratory Network (ILN). The ILN brings together scientific instrumentation, Internet-based classroom management systems (CMS), and other online resources to provide a new working model for the use and introduction of instrumentation within the undergraduate curriculum. Full implementation of the ILN will allow greater access to instruments and instrumental data and will provide a wide variety of novel teaching and learning opportunities. Examples of how the ILN has been implemented and used in a number of courses, including a high school chemistry course, are described.

  3. Extracellular Enzymes Lab Biochemistry

    E-print Network

    Vallino, Joseph J.

    Extracellular Enzymes Lab Biochemistry · All organisms convert small organic compounds shown here: All of these reactions, of which there are more than 1000, are catalyzed by enzymes. Glucose Phosphate PathwayEMP Pathway #12;Amino Acids #12;More Complete Metabolic Network TOP #12;#12;Enzymes

  4. Extracellular Enzymes Lab Biochemistry

    E-print Network

    Vallino, Joseph J.

    Extracellular Enzymes Lab Biochemistry · All organisms convert small organic compounds by enzymes. Glucose (C6) Pentose (C5) Triose (C3) Pyruvate (C3) AcetylCoA (C2) Citrate (C6) Oxoglutarate (C5 Cycle Pentose Phosphate PathwayEMP Pathway #12;More Complete Metabolic Network TOP #12;#12;Enzymes

  5. Extracellular Enzymes Lab Biochemistry

    E-print Network

    Vallino, Joseph J.

    Extracellular Enzymes Lab Biochemistry · All organisms convert small organic compounds, of which there are more than 1000, are catalyzed by enzymes. Glucose (C6) Pentose (C5) Triose (C3) Pyruvate Complete Metabolic Network TOP #12;#12;Enzymes · Enzymes are large proteins that all organisms synthesize

  6. Biotechnology and Applied Biochemistry

    E-print Network

    Yang, Jian

    Biotechnology and Applied Biochemistry A new generation of sodium chloride porogen for tissue engineering. Sodium chloride (NaCl) is the most commonly used porogen, but the current grinding and sieving control salt crystal sizes down to a few microns within a narrow size distribution. The resulting Na

  7. Biochemistry Off the Shelf.

    ERIC Educational Resources Information Center

    Wilson, Jerry L.

    1985-01-01

    Provides sources of nonanimal biochemical materials (which are relatively inexpensive, readily available, and require no special storage) suitable for use in biochemistry experiments. They are presented under these headings: (1) enzymes and other proteins; (2) carbohydrates; (3) lipids; (4) nucleic acids; and (5) metabolism. (JN)

  8. The Genomics Education Partnership: Successful Integration of Research into Laboratory Classes at a Diverse Group of Undergraduate Institutions

    ERIC Educational Resources Information Center

    Shaffer, Christopher D.; Alvarez, Consuelo; Bailey, Cheryl; Barnard, Daron; Bhalla, Satish; Chandrasekaran, Chitra; Chandrasekaran, Vidya; Chung, Hui-Min; Dorer, Douglas R.; Du, Chunguang; Eckdahl, Todd T.; Poet, Jeff L.; Frohlich, Donald; Goodman, Anya L.; Gosser, Yuying; Hauser, Charles; Hoopes, Laura L. M.; Johnson, Diana; Jones, Christopher J.; Kaehler, Marian; Kokan, Nighat; Kopp, Olga R.; Kuleck, Gary A.; McNeil, Gerard; Moss, Robert; Myka, Jennifer L.; Nagengast, Alexis; Morris, Robert; Overvoorde, Paul J.; Shoop, Elizabeth; Parrish, Susan; Reed, Kelynne; Regisford, E. Gloria; Revie, Dennis; Rosenwald, Anne G.; Saville, Ken; Schroeder, Stephanie; Shaw, Mary; Skuse, Gary; Smith, Christopher; Smith, Mary; Spana, Eric P.; Spratt, Mary; Stamm, Joyce; Thompson, Jeff S.; Wawersik, Matthew; Wilson, Barbara A.; Youngblom, Jim; Leung, Wilson; Buhler, Jeremy; Mardis, Elaine R.; Lopatto, David; Elgin, Sarah C. R.

    2010-01-01

    Genomics is not only essential for students to understand biology but also provides unprecedented opportunities for undergraduate research. The goal of the Genomics Education Partnership (GEP), a collaboration between a growing number of colleges and universities around the country and the Department of Biology and Genome Center of Washington…

  9. Modeling Stretching Modes of Common Organic Molecules with the Quantum Mechanical Harmonic Oscillator: An Undergraduate Vibrational Spectroscopy Laboratory Exercise

    ERIC Educational Resources Information Center

    Parnis, J. Mark; Thompson, Matthew G. K.

    2004-01-01

    An introductory undergraduate physical organic chemistry exercise that introduces the harmonic oscillator's use in vibrational spectroscopy is developed. The analysis and modeling exercise begins with the students calculating the stretching modes of common organic molecules with the help of the quantum mechanical harmonic oscillator (QMHO) model.

  10. Analysis of Bromination of Ethylbenzene Using a 45 MHz NMR Spectrometer: An Undergraduate Organic Chemistry Laboratory Experiment

    ERIC Educational Resources Information Center

    Isaac-Lam, Meden F.

    2014-01-01

    A 45 MHz benchtop NMR spectrometer is used to identify the structures and determine the amount of 1-bromoethylbenzene and 1,1-dibromoethylbenzene produced from free-radical bromination of ethylbenzene. The experiment is designed for nonchemistry majors, specifically B.S. Biology students, in a predominantly undergraduate institution with…

  11. Bioinformatics in Undergraduate Education: Practical Examples

    ERIC Educational Resources Information Center

    Boyle, John A.

    2004-01-01

    Bioinformatics has emerged as an important research tool in recent years. The ability to mine large databases for relevant information has become increasingly central to many different aspects of biochemistry and molecular biology. It is important that undergraduates be introduced to the available information and methodologies. We present a…

  12. Undergraduate Marine Science Program Student Advising Guide

    E-print Network

    Miami, University of

    areas, coastal and ocean law, and marine cultural resources Marine Science/Biology Marine biologists interested in these latter areas should also consider Marine Science/Biochemistry and Molecular BiologyUndergraduate Marine Science Program Student Advising Guide 2014-2015 #12;TABLE OF CONTENTS 1

  13. Biochemistry (by Jochanan Stenesh)

    NASA Astrophysics Data System (ADS)

    Glasfeld, Arthur

    1999-06-01

    Plenum: New York, 1998. Hardcover, ISBN 0 306-45732-6. 95. Paperback, ISBN 0 306 45733 4. 55 (set of 3). Solutions manual and transparencies available. According to the promotional materials accompanying this text, its intended audience is students in one-semester undergraduate biochemistry courses. At just over 500 pages, the book is shorter than the norm of well over 1000 pages. The challenge, then, is to present the subject in a coherent and compelling fashion while necessarily omitting a large fraction of the material that one normally finds in more inclusive texts. That kind of editing is obviously going to lead to squawking from some quarters, so I should put my prejudices on the table. I teach a one-semester course in biochemical structure, and I have a long-standing interest in using molecular models to explain biochemical behavior, both in research and in teaching. The editing performed by Professor Stenesh is likely to trouble someone with a structural or mechanistic background. Rather than selectively excluding some topics, Stenesh has created a table of contents that looks like it's from a much longer text. The usual chapters on biochemical structure, catalysis, metabolism and molecular genetics are included here. The ax fell elsewhere, and most obvious to my eye are the omissions of structure and chemical mechanism beyond those few chapters that are dedicated to them. A brief presentation on the structure and function of hemoglobin is given in the chapter on proteins, and the catalytic mechanism of chymotrypsin is briefly presented in the chapter on catalysis. But in chapters on metabolism, the structures of substrates and products are shown while mechanisms of conversion are omitted. For example, in the description of aldolase, we're informed that the enzyme catalyzes a reverse aldol condensation, but the reader isn't shown how the aldol condensation relates to the chemical conversion we see in the figure. (Part of the problem may be that the text assumes only one semester of preparation in organic chemistry, which might not be adequate for a discussion of biochemical mechanism.) In the section on gene regulation, no mention is made of the atomic-level interactions between regulatory proteins and DNA that lead to specific, high-affinity binding. The helix-turn-helix motif isn't even mentioned. Obviously, in a 500-page text, something had to go. It's too bad, though, that the omitted material includes the structural and mechanistic explanations for the chemical transformations and cellular processes being described. These complaints shouldn't overshadow the fact that this is a thoughtfully constructed text. The writing is both clear and simple. Broken into subsections, topics are presented in brief synopses that carefully identify key terms and ideas, and the problems at the back of the chapters are plentiful and appropriate. Stenesh's presentation is logically sound. I appreciated the presentation of thermodynamics in a chapter that directly precedes metabolism, rather than the more common brief review that appears in the earliest chapters. Likewise, the inclusion of enzyme catalysis directly after protein structure works in the context of this text. I noted a few small errors, but nothing that would cause distractions for the student. Unfortunately, the two-color graphics that accompany the text are less than compelling by current standards (also, a relatively greater number of errors appear in the figures). In drawing chemical structures, little effort is made to show molecular shape. For example, the figures use Fischer projections (without definition before Chapter 5) to define stereoisomers, and only in the appendix are dashes and wedges used to define them. This is particularly problematic in the chapter on amino acids, where their chirality is described but never illustrated. It is difficult to see the three-dimensional concepts being presented in the two-dimensional format being used. In topics where good visuals would be most useful (such as protein and DNA structure), the figures are reminiscent o

  14. Synthesis and Application of Ratiometric and "Turn-On" Fluorescent pH Sensors: An Advanced Organic Undergraduate Laboratory

    ERIC Educational Resources Information Center

    Hutt, Johnathon T.; Aron, Zachary D.

    2014-01-01

    An upper-division organic chemistry laboratory experiment exploring fluorescent sensing over two laboratory periods and part of a third is described. Two functionally distinct pH-responsive sensors are prepared through a dehydrative three-component coupling reaction. During the abbreviated (<1 h) first laboratory period, students set up…

  15. UNDERGRADUATE SCHOLARSHIPS

    E-print Network

    Barthelat, Francois

    UNDERGRADUATE SCHOLARSHIPS ANDAWARDS UNIVERSITY CALENDAR 2011/12 #12;McGill University, Undergraduate Scholarships and Awards 2011-2012 1 About This Calendar Published by Enrolment Services 3415 McGill University, Undergraduate Scholarships and Awards 2011-2012 3 Undergraduate Scholarships and Awards 2011

  16. Positron Emission Tomography (PET) and Graphical Kinetic Data Analysis of the Dopamine Neurotransmitter System: An Exercise for an Undergraduate Laboratory Course

    PubMed Central

    Mirrione, Martine M.; Ruth, Nora; Alexoff, David; Logan, Jean; Fowler, Joanna; Kernan, Maurice

    2014-01-01

    Neuroimaging techniques, including positron emission tomography (PET), are widely used in clinical settings and in basic neuroscience research. Education in these methods and their applications may be incorporated into curricula to keep pace with this expanding field. Here, we have developed pedagogical materials on the fundamental principles of PET that incorporate a hands-on laboratory activity to view and analyze human brain scans. In this activity, students will use authentic PET brain scans generated from original research at Brookhaven National Laboratory (Volkow et al., 2009) to explore the neurobiological effects of a drug on the dopamine system. We provide lecture and assignment materials (including a 50-minute PowerPoint presentation introducing PET concepts), written background information for students and instructors, and explicit instructions for a 4-hour, computer-based laboratory to interested educators. Also, we discuss our experience implementing this exercise as part of an advanced undergraduate laboratory course at Stony Brook University in 2010 and 2011. Observing the living human brain is intriguing, and this laboratory is designed to illustrate how PET neuroimaging techniques are used to directly probe biological processes occurring in the living brain. Laboratory course modules on imaging techniques such as PET can pique the interest of students potentially interested in neuroscience careers, by exposing them to current research methods. This activity provides practical experience analyzing PET data using a graphical analysis method known as the Logan plot, and applies core neuropharmacology concepts. We hope that this manuscript inspires college instructors to incorporate education in PET neuroimaging into their courses. PMID:24693258

  17. Biochemistry Insect Biochemistry and Molecular Biology 36 (2006) 210218

    E-print Network

    Qin, Wensheng

    2006-01-01

    Insect Biochemistry and Molecular Biology Insect Biochemistry and Molecular Biology 36 (2006) 210­218 Characterization of antifreeze protein gene expression in summer spruce budworm larvae Wensheng Qin1 , Michael G. Tyshenko1 , Daniel Doucet, Virginia K. Walkerà Department of Biology, Queen's University, Kingston, Ont

  18. Teaching cardiac electrophysiology modeling to undergraduate students: laboratory exercises and GPU programming for the study of arrhythmias and spiral wave dynamics

    NSDL National Science Digital Library

    Ezio Bartocci (Stony Brook University)

    2011-12-01

    As part of a 3-wk intersession workshop funded by a National Science Foundation Expeditions in Computing award, 15 undergraduate students from the City University of New York collaborated on a study aimed at characterizing the voltage dynamics and arrhythmogenic behavior of cardiac cells for a broad range of physiologically relevant conditions using an in silico model. The primary goal of the workshop was to cultivate student interest in computational modeling and analysis of complex systems by introducing them through lectures and laboratory activities to current research in cardiac modeling and by engaging them in a hands-on research experience. Results from these simulations, as well as some of the background and methodology taught during the workshop, is presented in this article along with the programming code and the explanations of simulation results in an effort to allow other teachers and students to perform their own demonstrations, simulations, and studies.

  19. The use of multiple tools for teaching medical biochemistry.

    PubMed

    Sé, Alexandre B; Passos, Renato M; Ono, André H; Hermes-Lima, Marcelo

    2008-03-01

    In this work, we describe the use of several strategies employing the philosophies of active learning and problem-based learning (PBL) that may be used to improve the teaching of metabolic biochemistry to medical and nutritional undergraduate students. The main activities are as follows: 1) a seminar/poster system in a mini-congress format (using topics of applied biochemistry); 2) a true/false applied biochemistry exam (written by peer tutors); 3) a 9-h exam on metabolism (based in real publications); 4) the Advanced Biochemistry course (directed to peer tutors, where students learn how to read and criticize real medical papers); 5) experiments about nutrition and metabolism, using students as volunteers, and about free radicals (real science for students); 6) the BioBio blog (taking advantage of the "web age," this enhances out of class exchanges of information between the professor, students, and peer tutors); 7) student lectures on public health issues and metabolic disorders directed to the community and lay people; and 8) the BioBio quiz show. The main objective of these activities is to provide students with a more practical and interesting approach to biochemistry, such as the application of theoretical knowledge to real situations (diseases, experiments, media information, and scientific discoveries). In addition, we emphasize the importance of peer tutor activities for optimized learning of both students and peer tutors, the importance of a closer interaction between students and teaching staff, and the necessity to initiate students precociously in two broad fields of medical activity: "real" basic science and contact with the public (also helping students--future doctors and nutritionists--to be able to communicate with lay people). Most activities were evaluated by the students through written questionnaires and informal conversations, along various semesters, indicating good acceptance and approval of these methods. Good student scores in the biochemistry exams and seminars indicated that these activities are also working as valid educational tools. PMID:18334567

  20. Extending students' practice of metacognitive regulation strategies in the undergraduate chemistry laboratory and investigation of Pb2+ binding to calmodulin with circular dichroism and molecular dynamics modeling

    NASA Astrophysics Data System (ADS)

    Valencia Navarro, Laura N.

    The following dissertation was composed of two projects in chemistry education and benchwork/computational biochemistry. The chemistry education research explored students' practice of metacognitive strategies while solving open-ended laboratory problems when engaged in an instructional environment, the Science Writing Heuristic (SWH), that was characterized as supporting metacognitive regulation strategy use. Through in-depth interviews with students, results demonstrated that students in the SWH environment, compared to non-SWH students, used metacognitive strategies to a greater degree and to a greater depth when solving open-ended laboratory problems. As students engaged in higher levels of metacognitive regulation, their elective use of peers became a prominent path for supporting the practice of metacognitive strategies. Students claimed that the structure of the SWH weekly laboratory experiments improved their ability to solve open-ended lab problems. This research not only provided a lens into students' descriptions of their regulation strategy practices in the laboratory, but it also supported that the way that a laboratory environment is arranged can affect these regulation strategy practices and their transfer to new situations. In the biochemical study on the binding of Pb2+ to calmodulin (CaM), data was acquired via circular dichroism (CD) and molecular dynamics modeling. CD signal data indicated a unique signal from Pb-CaM and a significantly smaller ratio theta208/theta222 for Pb-CaM than Ca-CaM. An analysis of secondary structure content indicated that alpha-helical structure decreased and random coil structure increased when CaM was saturated with Pb2+ compared to Ca2+ saturated CaM. A molecular dynamics simulation of Pb2+ binding to CaM showed that Pb2+ ions bound to sites outside of the known canonical binding sites including the linker region, and indicated change in secondary structure. These results support the theory of opportunistic binding of Pb 2+ to CaM, and confirm previous research of binding sites in the linker region (Met 76 to Asp 84). The method of random ion (Pb2+ >) placement with a protein (CaM) in a water box provided an accurate prediction of binding sites, correctly predicting four of five binding sites found on both crystal structures of Pb-CaM.

  1. The use of U.S. Geological Survey CD-ROM-based petroleum assessments in undergraduate geology laboratories

    USGS Publications Warehouse

    Eves, R.L.; Davis, L.E.; Dyman, T.S.; Takahashi, K.I.

    2002-01-01

    Domestic oil production is declining and United States reliance on imported oil is increasing. America will be faced with difficult decisions that address the strategic, economic, and political consequences of its energy resources shortage. The geologically literate under-graduate student needs to be aware of current and future United States energy issues. The U.S. Geological Survey periodically provides energy assessment data via digitally-formatted CD-ROM publications. These publications are free to the public, and are well suited for use in undergraduate geology curricula. The U.S. Geological Survey (USGS) 1995 National Assessment of United States Oil and Gas Resources (Digital Data Series or DDS-30) (Gautier and others, 1996) is an excellent resource for introducing students to the strategies of hydrocarbon exploration and for developing skills in problem-solving and evaluating real data. This paper introduces the reader to DDS-30, summarizes the essential terminology and methodology of hydrocarbon assessment, and offers examples of exercises or questions that might be used in the introductory classroom. The USGS contact point for obtaining DDS-30 and other digital assessment volumes is also provided. Completing the sample exercises in this report requires a copy of DDS-30.

  2. Biosciences Biochemistry and Cell Biology

    E-print Network

    Richards-Kortum, Rebecca

    111 Biosciences Biochemistry and Cell Biology The Wiess School of Natural Sciences Chair George N Biology The Wiess School of Natural Sciences Chair Ronald L. Sass Professors Paul A. Harcombe David C of Biochemistry and Cell Biology and the Department of Ecology and Evolutionary Biology. This curriculum offers

  3. Thiol biochemistry of prokaryotes

    NASA Technical Reports Server (NTRS)

    Fahey, Robert C.

    1986-01-01

    The present studies have shown that GSH metabolism arose in the purple bacteria and cyanobacteria where it functions to protect against oxygen toxicity. Evidence was obtained indicating that GSH metabolism was incorporated into eucaryotes via the endosymbiosis giving rise to mitochrondria and chloroplasts. Aerobic bacteria lacking GSH utilize other thiols for apparently similar functions, the thiol being coenzyme A in Gram positive bacteria and chi-glutamylcysteine in the halobacteria. The thiol biochemistry of prokaryotes is thus seen to be much more highly diversified than that of eucaryotes and much remains to be learned about this subject.

  4. A Multistep Organocatalysis Experiment for the Undergraduate Organic Laboratory: An Enantioselective Aldol Reaction Catalyzed by Methyl Prolinamide

    ERIC Educational Resources Information Center

    Wade, Edmir O.; Walsh, Kenneth E.

    2011-01-01

    In recent years, there has been an explosion of research concerning the area of organocatalysis. A multistep capstone laboratory project that combines traditional reactions frequently found in organic laboratory curriculums with this new field of research is described. In this experiment, the students synthesize a prolinamide-based organocatalyst…

  5. Reinforcing the Links between Teaching and Research: Evaluation of a Scheme to Employ Undergraduate Students as Laboratory Assistants

    ERIC Educational Resources Information Center

    Hughes, Monica; Brown, Kate; Calvert, Jane

    2008-01-01

    A scheme was introduced to offer opportunities to second-year bioscience students to undertake part-time paid work in research laboratories. The aim was to provide students with a greater appreciation of bioscience research, to reinforce their laboratory skills and to encourage them to consider a research-based career. Students worked for 8 hours…

  6. Plant residue biochemistry regulates soil carbon cycling and carbon sequestration

    Microsoft Academic Search

    Dean A. Martens

    2000-01-01

    Substrate composition is one of the most important factors influencing the decomposition of plant residues in soils. The interaction of organic residue biochemistry with residue decomposition rates, soil aggregation and soil humus composition was determined in a laboratory experiment. Addition of seven different organic residues (2% w\\/w alfalfa, oat, canola, clover, soybean, corn and prairie grasses) to a Webster soil

  7. Internet resources and biochemistry.

    PubMed

    Bid, H K; Kumar, Ajay; Mittal, R D

    2006-03-01

    The Internet is a massive expanding body of information, which is likely to play a significant role for clinical Biochemists and researchers in patient health care across the world. This expansion has been matched by an increase in the number of individuals using the Internet. Since its inception in December 1969 the Internet has grown rapidly and is anticipated to expand 100% in the coming next few years. This review illustrates to the Biochemists many uses of the Internet and hopefully provides a useful resource for professional and personal use. To explain the origin, functions, use and impact of the Internet and to provide a list of important website addresses related to Biochemistry. We undertook a detail scan of the Internet and identified a large number of websites pertaining to Biochemistry. The sites were then thoroughly searched to evaluate their potential usefulness to Biochemists, clinicians and researchers. This overview of the Internet and a compilation of important web-site addresses are expected to stimulate and inculcate Biochemists in the use of the web in teaching, training and research. PMID:23105585

  8. Unsteady-State Heat Transfer Involving a Phase Change: An Example of a 'Project-Oriented' Undergraduate Laboratory.

    ERIC Educational Resources Information Center

    Sundberg, Donald C.; Someshwar, Arun V.

    1989-01-01

    Describes the structure of an in-depth laboratory project chemical engineering. Provides modeling work to guide experimentation and experimental work on heat transfer analysis. Discusses the experimental results and evaluation of the project. (YP)

  9. A Western Blot-based Investigation of the Yeast Secretory Pathway Designed for an Intermediate-Level Undergraduate Cell Biology Laboratory

    PubMed Central

    2008-01-01

    The movement of newly synthesized proteins through the endomembrane system of eukaryotic cells, often referred to generally as the secretory pathway, is a topic covered in most intermediate-level undergraduate cell biology courses. An article previously published in this journal described a laboratory exercise in which yeast mutants defective in two distinct steps of protein secretion were differentiated using a genetic reporter designed specifically to identify defects in the first step of the pathway, the insertion of proteins into the endoplasmic reticulum (Vallen, 2002). We have developed two versions of a Western blotting assay that serves as a second way of distinguishing the two secretory mutants, which we pair with the genetic assay in a 3-wk laboratory module. A quiz administered before and after students participated in the lab activities revealed significant postlab gains in their understanding of the secretory pathway and experimental techniques used to study it. A second survey administered at the end of the lab module assessed student perceptions of the efficacy of the lab activities; the results of this survey indicated that the experiments were successful in meeting a set of educational goals defined by the instructor. PMID:18316814

  10. UNDERGRADUATE SCHOLARSHIPS

    E-print Network

    Barthelat, Francois

    UNDERGRADUATE SCHOLARSHIPS ANDAWARDS UNIVERSITY CALENDAR 2013/14 #12;McGill University, Undergraduate Scholarships and Awards 2013­2014 1 About This Calendar Published by Enrolment Services 3415 Mc Enrolment Services Cover Design Public Affairs, Graphic Design #12;UNDERGRADUATE SCHOLARSHIPS AND AWARDS 2

  11. Undergraduate Scholarships

    E-print Network

    Hampton, Randy

    Continuing Undergraduate Scholarships 2011-2012 GUIDELINES Apply on-line through Triton June 2011 Questions: scholarships@ucsd.edu (858) 534-1067 Undergraduate Scholarship Program Scholarships are awarded on a competitive basis, selected by the Faculty Committee on Undergraduate

  12. http://chemistry.usc.edu/ Tel: (213) 7407036 UndergraduateProgramsDepartment of Chemistry

    E-print Network

    Rohs, Remo

    http://chemistry.usc.edu/ Tel: (213) 7407036 UndergraduateProgramsDepartment of Chemistry Chemistry NanoscienceChemical BiologyBiochemistryResearch Five Majors, One Vision #12;Department of Chemistry, Undergraduate Programs Information about the programs B.S. degree in Chemistry: The B.S. degree in Chemistry

  13. Undergraduate Student Attitudes and Perceptions toward Low- and High-Level Inquiry Exercise Physiology Teaching Laboratory Experiences

    ERIC Educational Resources Information Center

    Henige, Kim

    2011-01-01

    The purpose of this investigation was to compare student attitudes toward two different science laboratory learning experiences, specifically, traditional, cookbook-style, low-inquiry level (LL) activities and a high-inquiry level (HL) investigative project. In addition, we sought to measure and compare students' science-related attitudes and…

  14. Determination of Spin-Lattice Relaxation of Time Using (Super 13)C NMR: An Undergraduate Physical Chemistry Laboratory Experiment

    ERIC Educational Resources Information Center

    Gasyna, Zbigniew L.; Jurkiewicz, Antoni

    2004-01-01

    An experiment designed for the physical chemistry laboratory where (super 13)C NMR is applied to determine the spin-lattice relaxation time for carbon atoms in n-hexanol is proposed. It is concluded that students learn the principles and concepts of NMR spectroscopy as well as dynamic NMR experiments.

  15. Genomics and Bioinformatics in Undergraduate Curricula: Contexts for Hybrid Laboratory/Lecture Courses for Entering and Advanced Science Students

    ERIC Educational Resources Information Center

    Temple, Louise; Cresawn, Steven G.; Monroe, Jonathan D.

    2010-01-01

    Emerging interest in genomics in the scientific community prompted biologists at James Madison University to create two courses at different levels to modernize the biology curriculum. The courses are hybrids of classroom and laboratory experiences. An upper level class uses raw sequence of a genome (plasmid or virus) as the subject on which to…

  16. Undergraduate Student Attitudes and Perceptions Toward Low- and High-Level Inquiry Exercise Physiology Teaching Laboratory Experiences

    NSDL National Science Digital Library

    2011-06-01

    This article describes findings on student attitudes toward two different science laboratory learning experiences, traditional, cookbook-style, low-inquiry level (LL) activities and a high-inquiry level (HL) investigative project. In addition, students' science-related attitudes and attitudes toward science were measured.

  17. A Comparison of Students' Attitudes Between Computer Software Support and Traditional Laboratory Practical Learning Environments in Undergraduate Electronics Science

    Microsoft Academic Search

    Y. B. Gandole

    The purpose of this experimental study was to see the effect of Computer software support on the attitude towards electronics subject of students while working in laboratory of electronics science. In this experimental study there were two groups as experimental group and control group. The experimental group performed the experiments using computer software support for selected practical in electronics, while

  18. Use of the Herb Gymnema sylvestre to Illustrate the Principles of Gustatory Sensation: An Undergraduate Neuroscience Laboratory Exercise

    NSDL National Science Digital Library

    Joseph Schroeder, Ellen Flannery-Schroeder (Conneticut College, University of Rhode Island; )

    1999-11-30

    This article describes a laboratory exercise used to illustrate the principles of gustatory sensation. The Indian herb, gymnema sylvestre, is used in this experiment to impair the ability of tasting sugar. As a result the impairment alters the perception of sweetness, which leaves a profound and lasting impression on students and gives them a better comprehension of gustation.

  19. A Simple LIBS (Laser-Induced Breakdown Spectroscopy) Laboratory Experiment to Introduce Undergraduates to Calibration Functions and Atomic Spectroscopy

    ERIC Educational Resources Information Center

    Chinni, Rosemarie C.

    2012-01-01

    This laboratory experiment introduces students to a different type of atomic spectroscopy: laser-induced breakdown spectroscopy (LIBS). LIBS uses a laser-generated spark to excite the sample; once excited, the elemental emission is spectrally resolved and detected. The students use LIBS to analyze a series of standard synthetic silicate samples…

  20. Survey of Biochemistry Course Syllabus

    E-print Network

    Houston, Paul L.

    The primary objective of this course is for students to learn the fundamentals of contemporary biochemistry and Kathleen Cornely Copyright 2010, John Wiley & Sons OTHER REQUIREMENTS Personal Response System Unit (Radio

  1. Cat dissection vs. sculpting human structures in clay: an analysis of two approaches to undergraduate human anatomy laboratory education.

    PubMed

    Waters, John R; Van Meter, Peggy; Perrotti, William; Drogo, Salvatore; Cyr, Richard J

    2005-03-01

    Many human anatomy courses are taught using cat dissection. Alternatives are available, but information regarding learning outcomes is incomplete. In 2003, approximately 120 undergraduates enrolled in a human anatomy course were assigned to one of two treatment groups. In the control group, students performed cat dissections (emphasizing isolation and identification) of the muscular, digestive, and cardiovascular systems. In the experimental treatment group, students built clay sculptures of each human body system. Student learning was evaluated by using both low- and high-difficulty questions. On pre- and postexperiment control exams, there were no significant differences in student performance. On exams after a cat dissection vs. a human-clay sculpting experience, the students in the human-clay sculpting treatment group scored significantly higher than their classmates in the cat dissection group on both the low- and high-difficulty questions. Student attitudes toward dissection and taking future human anatomy courses were also measured. There were no differences in student attitudes at the beginning of the experiment; afterward, students exposed to a cat dissection experience viewed dissection more favorably than students in the human-clay sculpting treatment group. There were no treatment effects on student willingness to take future human anatomy courses. The experimental design makes it difficult to conclude precisely why students assigned to the human-clay sculpting experience performed better on exams, but as each method was performed in this particular human anatomy course, our data indicate that human-clay sculpting may be a viable alternative to cat dissection in an anatomy course in which the students focus on human anatomy. PMID:15718380

  2. A Council on Undergraduate Research Workshop Initiative to Establish, Enhance, and Institutionalize Undergraduate Research

    ERIC Educational Resources Information Center

    Karukstis, Kerry K.

    2006-01-01

    The value of undergraduate research workshop to significantly enhance the quality of undergraduate science education was cited as one of the goals by the National Science Foundations (NSF) Strategic Plan. To address this strategic national need, the Council on Undergraduate Research (CUR) has granted an NSF course, curriculum, and laboratory

  3. THE JOURNAL OP BIOLOGICAL CHEMISTRY Q 1993 by The American Society for Biochemistry and Molecular Biology, Inc.

    E-print Network

    of Phnrmaco-Biology, Laboratory of Biochemistry and Molecular Biology, University of Bari, I-70125 Bari, ItalyTHE JOURNAL OP BIOLOGICAL CHEMISTRY Q 1993 by The American Society for Biochemistry and Molecular Biology, Inc. Vol. 268, No. 17, Issue of June 15, pp. 12977-12992,1993 Printed in U.S. A. Location

  4. AEROSPACE LABORATORY GENERAL INFORMATION MANUAL

    E-print Network

    Sislian, J. P.

    AEROSPACE LABORATORY GENERAL INFORMATION MANUAL 1. Introduction 2. Laboratory Format 3. Recommended Guidelines for Experiment Reports 4. Laboratory Notebooks 5. Report Marking Procedures 6. Course Mark compared to the systems you will find in the Undergraduate Laboratory. Typically, experimental setups

  5. Using a PyMOL activity to reinforce the connection between genotype and phenotype in an undergraduate genetics laboratory.

    PubMed

    Simmons, Alexandra D; Nguyen, Thao K T; Follis, Jack L; Ribes-Zamora, Albert

    2014-01-01

    With the purpose of developing an activity that would help clarify genetic concepts related to the connection between genotype and phenotype and the nature of mutations, we designed a three hour teaching module using the PyMol software. The activity starts with two pre-laboratory assignments, one to learn how to use PyMol and the other to read about a specific protein or protein family. During the laboratory students are given instructions where and how to find additional information on a specific disease and its causal mutations in order to prepare a 10-minute, in-class presentation. Using a post activity, anonymous quiz, we found a statistically significant different grade distribution in students that participated in the PyMol activity relative to a control group. We also found a significant improvement in the student's comprehension when answering questions regarding the nature of mutations and protein structure. This demonstrates the utility of this simulation activity as a vehicle to improve student's understanding of specific key genetic concepts. PMID:25461967

  6. Using a PyMOL Activity to Reinforce the Connection between Genotype and Phenotype in an Undergraduate Genetics Laboratory

    PubMed Central

    Simmons, Alexandra D.; Nguyen, Thao K. T.; Follis, Jack L.; Ribes-Zamora, Albert

    2014-01-01

    With the purpose of developing an activity that would help clarify genetic concepts related to the connection between genotype and phenotype and the nature of mutations, we designed a three hour teaching module using the PyMol software. The activity starts with two pre-laboratory assignments, one to learn how to use PyMol and the other to read about a specific protein or protein family. During the laboratory students are given instructions where and how to find additional information on a specific disease and its causal mutations in order to prepare a 10-minute, in-class presentation. Using a post activity, anonymous quiz, we found a statistically significant different grade distribution in students that participated in the PyMol activity relative to a control group. We also found a significant improvement in the student’s comprehension when answering questions regarding the nature of mutations and protein structure. This demonstrates the utility of this simulation activity as a vehicle to improve student’s understanding of specific key genetic concepts. PMID:25461967

  7. The Relevance of Student Seminars on Clinically Related Subjects in a Biochemistry Course for Medical and Nutrition Students

    ERIC Educational Resources Information Center

    Hermes-Lima, Marcelo; Muniz, Karinne C.; Coutinho, Iracema S.

    2002-01-01

    The aim of this study was to determine the value of a system of seminars on clinically related biochemistry topics for undergraduate students in medicine and nutrition at the University of Brasilia, Brazil. During the second semester of 1998 (1998-2), the teaching staff decided to establish new and stricter rules for the seminar method and to…

  8. Undergraduate Opportunities

    E-print Network

    Plotkin, Joshua B.

    Undergraduate Research Opportunities Program for US and Canadian Students at RWTH Aachen University fosters research partnerships between qualified undergraduates from top US and Canadian universities of the departments of RWTH Aachen University. Leisure activities will be offered to ensure the students' integration

  9. Undergraduate Researchers

    E-print Network

    Sibille, Etienne

    celebration of science and technology Science2011Next Gen http://www.science2011.pitt.edu/posters at the Undergraduate Research Poster Reception that will be part of the University of Pittsburgh's 11th annual.htm Undergraduate Research Poster Reception 5:00 p.m., Thursday, 6 October Connolly Ballroom, Alumni Hall

  10. A guide to using case-based learning in biochemistry education.

    PubMed

    Kulak, Verena; Newton, Genevieve

    2014-01-01

    Studies indicate that the majority of students in undergraduate biochemistry take a surface approach to learning, associated with rote memorization of material, rather than a deep approach, which implies higher cognitive processing. This behavior relates to poorer outcomes, including impaired course performance and reduced knowledge retention. The use of case-based learning (CBL) into biochemistry teaching may facilitate deep learning by increasing student engagement and interest. Abundant literature on CBL exists but clear guidance on how to design and implement case studies is not readily available. This guide provides a representative review of CBL uses in science and describes the process of developing CBL modules to be used in biochemistry. Included is a framework to implement a directed CBL assisted with lectures in a content-driven biochemistry course regardless of class size. Moreover, this guide can facilitate adopting CBL to other courses. Consequently, the information presented herein will be of value to undergraduate science educators with an interest in active learning pedagogies. PMID:25345695

  11. Samuel Szeto Department of Biochemistry

    E-print Network

    MacMillan, Andrew

    in the Department of Biochemistry. One of the main focuses of the lab centers on elucidating the structure, function function can produce severe physiological consequences resulting in a wide variety of clinical as a model system and a variety of biochemical, molecular biological and genetic techniques. After completing

  12. New challenges in computational biochemistry

    SciTech Connect

    Honig, B. [Columbia Univ., New York, NY (United States)

    1996-12-31

    The new challenges in computational biochemistry to which the title refers include the prediction of the relative binding free energy of different substrates to the same protein, conformational sampling, and other examples of theoretical predictions matching known protein structure and behavior.

  13. Laboratory Techniques for the Blind

    ERIC Educational Resources Information Center

    Tombaugh, Dorothy

    1972-01-01

    Describes modifications of laboratory procedures for the BSCS Green Version biology, including dissection, microbiology, animal behavior, physiology, biochemistry, and genetics that make the methods suitable for direct experimentation by blind students. Discusses models as substitutes for microscopy. (AL)

  14. BS in CHEMISTRY (692821) MAP Sheet Department of Chemistry and Biochemistry

    E-print Network

    Seamons, Kent E.

    455 Synthesis & Qualitative Organic Analysis Chem 462 Physical Chemistry Chem 463 Physical Chemistry Chem 464 Physical Chemistry Laboratory 1 Chem 465 Physical Chemistry Laboratory 2 Chem 481MBS in CHEMISTRY (692821) MAP Sheet Department of Chemistry and Biochemistry For students entering

  15. UCSD Department of Chemistry & Biochemistry, Teaching Laboratories LABORATORY REGULATIONS

    E-print Network

    Aluwihare, Lihini

    for quick reference. Prepare carefully. Attentive and considerate behavior is expected at all times to any prescription glasses. Chemical splash goggles are required whenever anyone is transferring more are not equipped to lend or sell goggles. With prescription glasses, choose goggles or safety glasses designed

  16. ENGINEERING UNDERGRADUATE

    E-print Network

    Walter, M.Todd

    ENGINEERING UNDERGRADUATE HANDBOOK Fall 2013 #12;Name: ____________________________________________________ E-mail: ____________________________________________________ College of Engineering Cornell University ABET Accredited Programs for 2013­14 ABET (Accreditation Board for Engineering and Technology

  17. Students' preferred teaching techniques for biochemistry in biomedicine and medicine courses.

    PubMed

    Novelli, Ethel L B; Fernandes, Ana Angélica H

    2007-07-01

    The aim of this study was to investigate the students' preferred teaching techniques, such as traditional blackboard, power-point, or slide-projection, for biochemistry discipline in biomedicine and medicine courses from São Paulo State University, UNESP, Botucatu, São Paulo, Brazil. Preferences for specific topic and teaching techniques were determined from questionnaires on a Liquert scale from 1 to 5 (strongly disagree; disagree; neither agree, nor disagree; agree; strongly agree) distributed at the end of biochemistry discipline to 180 biomedical students (30 students/year) and 540 medical students (90 students/year), during the years 2000-2005. Despite of the different number of hours applied to the course topics for the two groups of students, the majority of undergraduates from biomedicine and medicine preferred metabolic topics. Although the perception of a medical student is expected to be different than that of a biomedical student, as the aims of the two programs are different, 92.4% of students from each course agreed or strongly agreed with the biochemistry topics, and 92.1% thought highly on this subject. The majority of students, a number of 139 undergraduates from biomedicine and 419 from medicine course, preferred traditional blackboard teaching than slide-projection, or power-point class. In conclusion, it is imperative that the health courses reflect on sophisticated technology and data presentation with high density of information in biochemistry discipline. The traditional classes with blackboard presentation were most favored by students from biomedicine and medicine courses. The use of students' preferred teaching techniques might turn biochemistry more easily understood for biomedical and medical students. PMID:21591103

  18. Raman Spectroscopy for the Undergraduate Teaching Laboratory: Quantification of Ethanol Concentration in Consumer Alcoholic Beverages and Qualitative Identification of Marine Diesels Using a Miniature Raman Spectrometer

    Microsoft Academic Search

    Danielle Cleveland; Matthew Carlson; Evan D. Hudspeth; Lauren E. Quattrochi; Kathleen L. Batchler; Shrimati A. Balram; Seongun Hong; Robert G. Michel

    2007-01-01

    Raman spectroscopy has steadily gained popularity as a powerful tool in both the analytical lab and the undergraduate classroom. The technique is attractive because it allows for rapid, nondestructive qualitative or quantitative analyses of many analytes with little or no sample preparation requirements. The introduction of less expensive, smaller, and more powerful diode laser excitation sources and the recent availability

  19. Wanderings in Biochemistry

    PubMed Central

    Lengyel, Peter

    2014-01-01

    My Ph.D. thesis in the laboratory of Severo Ochoa at New York University School of Medicine in 1962 included the determination of the nucleotide compositions of codons specifying amino acids. The experiments were based on the use of random copolyribonucleotides (synthesized by polynucleotide phosphorylase) as messenger RNA in a cell-free protein-synthesizing system. At Yale University, where I joined the faculty, my co-workers and I first studied the mechanisms of protein synthesis. Thereafter, we explored the interferons (IFNs), which were discovered as antiviral defense agents but were revealed to be components of a highly complex multifunctional system. We isolated pure IFNs and characterized IFN-activated genes, the proteins they encode, and their functions. We concentrated on a cluster of IFN-activated genes, the p200 cluster, which arose by repeated gene duplications and which encodes a large family of highly multifunctional proteins. For example, the murine protein p204 can be activated in numerous tissues by distinct transcription factors. It modulates cell proliferation and the differentiation of a variety of tissues by binding to many proteins. p204 also inhibits the activities of wild-type Ras proteins and Ras oncoproteins. PMID:24867946

  20. Council on Undergraduate Research on the Web

    NSDL National Science Digital Library

    2012-02-03

    The mission of the Council of Undergraduate Research (CUR) is to "support and promote high-quality undergraduate student-faculty collaborative research and scholarship." CUR disseminates some of its work and findings through the Council of Undergraduate Research Quarterly (CURQ) and this site provides access to some of the articles from that publication. Currently, visitors can search past articles back to 2008, and visitors can browse through articles like "Putting Undergraduate Research on the Map for Women," "Peer Mentoring in an Introductory Biology Laboratory," and "Undergraduate Research on Writing: Benefits to Faculty and Curriculum Development." All told, the site provides a cornucopia of articles related to making the undergraduate research experience a bit more meaningful, and educators will find much to enjoy here.

  1. Secondary Science Teacher Certification Requirements Undergraduate Program

    E-print Network

    Maryland, Baltimore County, University of

    Secondary Science Teacher Certification Requirements Biology Undergraduate Program Candidate Laboratory BIOL 301 Ecology and Evolution BIOL 302 Molecular and General Genetics BIOL 302L Molecular and General Genetics Laboratory BIOL 303 Cell Biology BIOL 303L Cell Biology Laboratory BIOL 304 Plant Biology

  2. Secondary Science Teacher Certification Requirements Undergraduate Program

    E-print Network

    Maryland, Baltimore County, University of

    Secondary Science Teacher Certification Requirements Chemistry Undergraduate Program Candidate CHEM 351L Organic Laboratory I CHEM 352L Organic Laboratory II CHEM 300 Analytical Chemistry CHEM 301 Physical Chemistry I CHEM 302 Physical Chemistry II CHEM 311L Advanced Laboratory I CHEM 405 Inorganic

  3. Common student misconceptions in exercise physiology and biochemistry

    NSDL National Science Digital Library

    James P. Morton (Liverpool John Moores University Research Institute for Sport and Exercise Sciences)

    2008-01-28

    The present study represents a preliminary investigationdesigned to identify common misconceptions in students' understanding of physiological and biochemical topics within the academic domain of sport and exercise sciences. A specifically designed misconception inventory (consisting of 10 multiple-choice questions) was administered to a cohort of level 1, 2, and 3 undergraduate students enrolled in physiology and biochemistry-related modules of the BSc Sport Science degree at the authors' institute. Of the 10 misconceptions proposed by the authors, 9 misconceptions were confirmed. Of these nine misconceptions, only one misconception appeared to have been alleviated by the current teaching strategy employed during the progression from level 1 to 3 study. The remaining eight misconceptions prevailed throughout the course of the degree program, suggesting that students enter and leave university with the same misconceptions in certain areas of exercise physiology and biochemistry. The possible origins of these misconceptions are discussed, as are potential teaching strategies to prevent and/or remediate them for future years.

  4. Ethanol Metabolism and the Transition from Organic Chemistry to Biochemistry

    NASA Astrophysics Data System (ADS)

    Feinman, Richard D.

    2001-09-01

    To ease the transition from organic chemistry at the beginning of a biochemistry course or at the beginning of the metabolism section of the organic course, an early presentation of the oxidation of ethanol is proposed. Alcohol dehydrogenase and aldehyde dehydrogenase reactions can smooth the introduction to biochemistry, since they involve three of the simplest compounds: ethanol, acetaldehyde, and acetic acid. Using these reactions as a model encourages the study of metabolic pathways by a systematic approach rather than by rote memorization. Reactions that can be presented as variations on a theme include methanol poisoning, the polyol reaction, and, most important, the sequence glycerol-3-phosphate to glyceraldehyde-3-phosphate to 3-phosphoglyceric acid. This last sequence integrates lipid and carbohydrate metabolism and, by comparison with the model reaction, brings out the principles of substrate-level phosphorylation. The method has evoked favorable verbal feedback from students and, in addition to medical and graduate courses, has been successfully used in the biochemical section of an undergraduate organic course.

  5. The power of undergraduate research

    Microsoft Academic Search

    E. O'Neill-Carrillo; M. Velez-Reyes; A. Irizarry-Rivera; E. Marrero

    2003-01-01

    Over the years, the power engineering program at the University of Puerto Rico-Mayaguez (UPRM) has prepared engineers to deal successfully with industry challenges. An important strategy in a power engineering curriculum renovation has been to give a more prominent role to undergraduate research. A new Energy Systems Instrumentation Laboratory (ESIL) has been established at UPRM to support the integration of

  6. Undergraduate Pharmacology

    E-print Network

    Bristol, University of

    Undergraduate Pharmacology Faculty of Medical and Veterinary Sciences #12;bristol.ac.uk/study Pharmacology is the study of the action of `drugs' in the widest possible sense, encompassing many types and the relief of both human and animal suffering. Pharmacology is closely allied to related disciplines

  7. CH 360 PHYSIOLOGICAL BIOCHEMISTRY Course Content

    E-print Network

    Richmond, Geraldine L.

    CH 360 PHYSIOLOGICAL BIOCHEMISTRY FALL 2008 Course Content: In this one-term term biochemistry is NOT a physiology class!). The course will begin with a consideration of cellular energy, amino acids, or any other electronic devices will not be allowed during class time. #12;CH 360 Physiological

  8. Teaching foundational topics and scientific skills in biochemistry within the conceptual framework of HIV protease.

    PubMed

    Johnson, R Jeremy

    2014-01-01

    HIV protease has served as a model protein for understanding protein structure, enzyme kinetics, structure-based drug design, and protein evolution. Inhibitors of HIV protease are also an essential part of effective HIV/AIDS treatment and have provided great societal benefits. The broad applications for HIV protease and its inhibitors make it a perfect framework for integrating foundational topics in biochemistry around a big picture scientific and societal issue. Herein, I describe a series of classroom exercises that integrate foundational topics in biochemistry around the structure, biology, and therapeutic inhibition of HIV protease. These exercises center on foundational topics in biochemistry including thermodynamics, acid/base properties, protein structure, ligand binding, and enzymatic catalysis. The exercises also incorporate regular student practice of scientific skills including analysis of primary literature, evaluation of scientific data, and presentation of technical scientific arguments. Through the exercises, students also gain experience accessing computational biochemical resources such as the protein data bank, Proteopedia, and protein visualization software. As these HIV centered exercises cover foundational topics common to all first semester biochemistry courses, these exercises should appeal to a broad audience of undergraduate students and should be readily integrated into a variety of teaching styles and classroom sizes. PMID:24652697

  9. Comprehensive Experiment--Clinical Biochemistry: Determination of Blood Glucose and Triglycerides in Normal and Diabetic Rats

    ERIC Educational Resources Information Center

    Jiao, Li; Xiujuan, Shi; Juan, Wang; Song, Jia; Lei, Xu; Guotong, Xu; Lixia, Lu

    2015-01-01

    For second year medical students, we redesigned an original laboratory experiment and developed a combined research-teaching clinical biochemistry experiment. Using an established diabetic rat model to detect blood glucose and triglycerides, the students participate in the entire experimental process, which is not normally experienced during a…

  10. Research and Teaching: Blooming, SOLO Taxonomy, and Phenomenography as Assessment Strategies in Undergraduate Science Education

    ERIC Educational Resources Information Center

    Newton, Genevieve; Martin, Elizabeth

    2013-01-01

    Three alternative approaches to assessment of exam responses were applied in an undergraduate biochemistry course. First, phenomenography was used to categorize written exam responses into an inclusive hierarchy. Second, responses to the same question were similarly categorized according to the Structure of Observed Learning Outcome (SOLO)…

  11. Hypothetical Biotechnology Companies: A Role-Playing Student Centered Activity for Undergraduate Science Students

    ERIC Educational Resources Information Center

    Chuck, Jo-Anne

    2011-01-01

    Science students leaving undergraduate programs are entering the biotechnology industry where they are presented with issues which require integration of science content. Students find this difficult as through-out their studies, most content is limited to a single subdiscipline (e.g., biochemistry, immunology). In addition, students need…

  12. Journal of Undergraduate Neuroscience Education

    NSDL National Science Digital Library

    This sharp looking website is for the Journal of Undergraduate Neuroscience Education (JUNE) which "publishes peer-reviewed reports of innovations in undergraduate neuroscience education...[and] serves as a mechanism for faculty to exchange information...such as laboratory exercises, new media, curricular considerations, and teaching methods." Visitors will find the "Supplementary Materials" tab near the top of any page to contain movies, lab instructions, papers, and images. Some of the movies include an adult and juvenile "Crayfish Brain Movie," "Larval Dissection Movie" of a drosophila mutant, and "Leg Prep and Spine Stimulation" of a cockroach. The "Previous Issues" tab gives visitors the opportunity to read issues published since 2002. Recent pieces featured in JUNE include "Integrating Community Outreach into the Undergraduate Neuroscience Classroom", "Design Plans for an Inexpensive Tail Flick Analgesia Meter", and "Unquenchable Neuroscience."

  13. BA in CHEMISTRY (692827) MAP Sheet Department of Chemistry and Biochemistry

    E-print Network

    Olsen Jr., Dan R.

    Biochemistry Lab/Nucleic Acids Stat 201 Stats for Engineers & Scientists OR Chem 462 Physical Chemistry Chem 463 Physical Chemistry Chem 464 Physical Chemistry Laboratory 1 Chem 465 Physical Chemistry Laboratory & Qualitative Organic Analysis Chem 462 Physical Chemistry 4.0 3.0 2.0 0.5 4.0 3.0 3.0 2.0 3.0 1.0 3.0 3.0 3.0 3

  14. BA in CHEMISTRY (692827) MAP Sheet Department of Chemistry and Biochemistry

    E-print Network

    Seamons, Kent E.

    Biochemistry Lab/Nucleic Acids Stat 121 Principles of Statistics OR Chem 462 Physical Chemistry Chem 463 Physical Chemistry Chem 464 Physical Chemistry Laboratory 1 Chem 465 Physical Chemistry Laboratory 2 Math Organic Analysis Chem 462 Physical Chemistry 3.0 3.0 2.0 0.5 4.0 3.0 3.0 2.0 3.0 1.0 3.0 3.0 3.0 (3.0 3

  15. Special-Study Modules in a Problem-Based Learning Medical Curriculum: An Innovative Laboratory Research Practice Supporting Introduction to Research Methodology in the Undergraduate Curriculum

    ERIC Educational Resources Information Center

    Guner, Gul Akdogan; Cavdar, Zahide; Yener, Nilgun; Kume, Tuncay; Egrilmez, Mehtap Yuksel; Resmi, Halil

    2011-01-01

    We describe the organization of wet-lab special-study modules (SSMs) in the Central Research Laboratory of Dokuz Eylul Medical School, Izmir, Turkey with the aim of discussing the scientific, laboratory, and pedagogical aspects of this educational activity. A general introduction to the planning and functioning of these SSMs is given, along with…

  16. Exploring the Structure-Function Relationship of Macromolecules at the Undergraduate Level

    ERIC Educational Resources Information Center

    Pastrana-Rios, Belinda

    2004-01-01

    The biochemistry laboratory course is structured such that students work in pairs during the first half of the course. The purpose is to encourage per-peer learning processes during the students' first exposure to the software.

  17. Promoting inquiry-based teaching in laboratory courses: are we meeting the grade?

    PubMed

    Beck, Christopher; Butler, Amy; da Silva, Karen Burke

    2014-01-01

    Over the past decade, repeated calls have been made to incorporate more active teaching and learning in undergraduate biology courses. The emphasis on inquiry-based teaching is especially important in laboratory courses, as these are the courses in which students are applying the process of science. To determine the current state of research on inquiry-based teaching in undergraduate biology laboratory courses, we reviewed the recent published literature on inquiry-based exercises. The majority of studies in our data set were in the subdisciplines of biochemistry, cell biology, developmental biology, genetics, and molecular biology. In addition, most exercises were guided inquiry, rather than open ended or research based. Almost 75% of the studies included assessment data, with two-thirds of these studies including multiple types of assessment data. However, few exercises were assessed in multiple courses or at multiple institutions. Furthermore, assessments were rarely based on published instruments. Although the results of the studies in our data set show a positive effect of inquiry-based teaching in biology laboratory courses on student learning gains, research that uses the same instrument across a range of courses and institutions is needed to determine whether these results can be generalized. PMID:25185228

  18. DEPARTMENTALLY-BASED SEMINAR SERIES 2012 Biochemistry

    E-print Network

    Yang, Sichun

    DEPARTMENTALLY-BASED SEMINAR SERIES 2012 Biochemistry Graduate Student Seminars- Mondays, 12:00pm and Biostatistics For seminar info: http://epbiwww.case.edu/index.php/events-a-seminars/seminar-info Victor Courtney

  19. The Biochemistry Tetrahedron and the Development of the Taxonomy of Biochemistry External Representations (TOBER)

    ERIC Educational Resources Information Center

    Towns, Marcy H.; Raker, Jeffrey R.; Becker, Nicole; Harle, Marissa; Sutcliffe, Jonathan

    2012-01-01

    Visual literacy, the ability to interpret and create external representations (ERs), is essential to success in biochemistry. Studies have been conducted that describe students' abilities to use and interpret specific types of ERs. However, a framework for describing ERs derived through a naturalistic inquiry of biochemistry classrooms has not…

  20. Undergraduate Admissions Director, Undergraduate Enrollment Programs: Karen S. Long

    E-print Network

    Varela, Carlos

    or transfer application forms available from the Office of Undergraduate Admissions. Rensselaer accepts35 Undergraduate Admissions Director, Undergraduate Enrollment Programs: Karen S. Long Contacting Rensselaer Admissions Information and application forms are available by contacting: Office of Undergraduate

  1. Introducing Education for Sustainable Development in the Undergraduate Laboratory: Quantitative Analysis of Bioethanol Fuel and Its Blends with Gasoline by Using Solvatochromic Dyes

    ERIC Educational Resources Information Center

    Galgano, Paula D.; Loffredo, Carina; Sato, Bruno M.; Reichardt, Christian; El Seoud, Omar A.

    2012-01-01

    The concept of "Education for Sustainable Development", ESD, has been introduced in a period where chemistry education is undergoing a major change, both in emphasis and methods of teaching. Studying an everyday problem, with an important socio-economic impact in the laboratory is a part of this approach. Presently, the students in many countries…

  2. Henry's Law Coefficient (Solubility) of Toluene in Water with GC-FID A laboratory experiment for junior level undergraduate Analytical Chemistry Lab course

    E-print Network

    Lee, Shan-Hu

    , R., Henrys Law constants (solubilities), http://www.mpch- mainz.mpg.de/~sander/res/henry.html#21 Henry's Law Coefficient (Solubility) of Toluene in Water with GC-FID A laboratory experiment is to measure Henrys Law coefficient (that is, solubility) of toluene in water with a gas chromatography (GC

  3. Using Structured Chemistry Examinations (SCHemEs) as an Assessment Method to Improve Undergraduate Students' Generic, Practical, and Laboratory-Based Skills

    ERIC Educational Resources Information Center

    Kirton, Stewart B.; Al-Ahmad, Abdullah; Fergus, Suzanne

    2014-01-01

    Increase in tuition fees means there will be renewed pressure on universities to provide "value for money" courses that provide extensive training in both subject-specific and generic skills. For graduates of chemistry this includes embedding the generic, practical, and laboratory-based skills associated with industrial research as an…

  4. What Is the True Color of Fresh Meat? A Biophysical Undergraduate Laboratory Experiment Investigating the Effects of Ligand Binding on Myoglobin Using Optical, EPR, and NMR Spectroscopy

    ERIC Educational Resources Information Center

    Linenberger, Kimberly; Bretz, Stacey Lowery; Crowder, Michael W.; McCarrick, Robert; Lorigan, Gary A.; Tierney, David L.

    2011-01-01

    With an increased focus on integrated upper-level laboratories, we present an experiment integrating concepts from inorganic, biological, and physical chemistry content areas. Students investigate the effects of ligand strength on the spectroscopic properties of the heme center in myoglobin using UV-vis, [superscript 1]H NMR, and EPR…

  5. Learning, Teaching and Scholarship: Fundamental Tensions of Undergraduate Research

    ERIC Educational Resources Information Center

    Laursen, Sandra; Seymour, Elaine; Hunter, Anne-Barrie

    2012-01-01

    Each year, thousands of undergraduates in the science, technology, engineering, and mathematics (STEM) fields conduct research in US university and college laboratories. Such undergraduate research (UR) experiences are common practice in US higher education, with nearly a century of history at research universities and liberal arts colleges.…

  6. John and Judy Hays Scholarship Fund for Undergraduate Research Training

    E-print Network

    Tullos, Desiree

    John and Judy Hays Scholarship Fund for Undergraduate Research Training Dr. John Hays received his to conduct mentored laboratory research. Donations to the John and Judy Hays Scholarship Fund for Undergraduate Research Training in any amount should be made "In honor of Dr. John and Judy Hays in support

  7. An Undergraduate Course in Modeling and Simulation of Multiphysics Systems

    ERIC Educational Resources Information Center

    Ortiz-Rodriguez, Estanislao; Vazquez-Arenas, Jorge; Ricardez-Sandoval, Luis A.

    2010-01-01

    An overview of a course on modeling and simulation offered at the Nanotechnology Engineering undergraduate program at the University of Waterloo. The motivation for having this course in the undergraduate nanotechnology curriculum, the course structure, and its learning objectives are discussed. Further, one of the computational laboratories

  8. Toward a Conceptual Framework for Measuring the Effectiveness of Course-Based Undergraduate Research Experiences in Undergraduate Biology

    ERIC Educational Resources Information Center

    Brownell, Sara E.; Kloser, Matthew J.

    2015-01-01

    Recent calls for reform have advocated for extensive changes to undergraduate science lab experiences, namely providing more authentic research experiences for students. Course-based Undergraduate Research Experiences (CUREs) have attempted to eschew the limitations of traditional "cookbook" laboratory exercises and have received…

  9. Integration of GC/MS Instrumentation into the Undergraduate Laboratory: Separation and Identification of Fatty Acids in Commercial Fats and Oils

    NASA Astrophysics Data System (ADS)

    Rubinson, Judith F.; Neyer-Hilvert, Jennifer

    1997-09-01

    A laboratory experiment using a gas chromatography/mass selective detection method has been developed for the isolation, identification, and quantitation of fatty acid content of commercial fats and oils. Results for corn, nutmeg, peanut, and safflower oils are compared with literature values, and the results for corn oil are compared for two different trials of the experiment. In addition, a number of variations on the experiment are suggested including possible extension of the experiment for use in an instrumental analysis course.

  10. Training Undergraduate Physics Peer Tutors

    NASA Astrophysics Data System (ADS)

    Nossal, S. M.; Jacob, A. T.

    2004-05-01

    The University of Wisconsin's Physics Peer Mentor Tutor Program matches upper level undergraduate physics students in small study groups with students studying introductory algebra-based physics. We work with students who are potentially at-risk for having academic trouble with the course. They include students with a low exam score, learning disabilities, no high school physics, weak math backgrounds, and/or on academic probation. We also work with students from groups under represented in the sciences and who may be feeling isolated or marginal on campus such as minority, returning adult, and international students. The tutors provide a supportive learning environment, extra practice problems, and an overview of key concepts. In so doing, they help our students to build confidence and problem solving skills applicable to physics and other areas of their academic careers. The Physics Peer Mentor Tutor Program is modeled after a similar program for chemistry created by the University of Wisconsin's Chemistry Learning Center. Both programs are now run in collaboration. The tutors are chosen for their academic strength and excellent communication skills. Our tutors are majoring in physics, math, and secondary-level science education. The tutors receive ongoing training and supervision throughout the year. They attend weekly discipline-specific meetings to discuss strategies for teaching the content currently being discussed in the physics course. They also participate in a weekly teaching seminar with science tutors from chemistry and biochemistry to discuss teaching methods, mentoring, and general information relating to the students with whom we work. We will describe an overview of the Physics Peer Mentor Tutor Program with a focus on the teacher training program for our undergraduate tutors.

  11. GPILS Intercampus Graduate Program in Biochemistry and Molecular Biology

    E-print Network

    Weber, David J.

    GPILS Intercampus Graduate Program in Biochemistry and Molecular Biology Student Handbook of Biochemistry and Molecular Biology 108 N. Greene Street Baltimore, MD 21201 (410) 706-8417 FAX: (410) 706 Governing Committee for 2014 - 2015 4 The Combined Ph.D. Program in Biochemistry and Molecular Biology A

  12. Bridging the Gap in Biochemistry between Secondary School and University

    ERIC Educational Resources Information Center

    Fernandez-Novell, Josep M.; Gomis, Roger R.; Cid, Emili; Barbera, Albert; Guinovart, Joan J.

    2002-01-01

    This manuscript describes a new strategy for introducing secondary school students to biochemistry. To bridge the gap between secondary education and the university, the Department of Biochemistry and Molecular Biology of the University of Barcelona, in collaboration with the SEBBM (The Spanish Society for Biochemistry and Molecular Biology),…

  13. Computer Science UNDERGRADUATE

    E-print Network

    Suzuki, Masatsugu

    . Computer Graphics CS 472. Compiler Design Programming Languages-- CS 340. Object-Oriented Programming #12447 Computer Science UNDERGRADUATE PROGRAMS The Department of Computer Science provides undergraduate instruction leading to the bachelor's degree in computer science. This program in computer science

  14. UW Summer STEM Undergraduate

    E-print Network

    Kaminsky, Werner

    UW Summer STEM Undergraduate Research Poster SessionWednesday, August 21st, 2013 9:00 am--12 noon to conduct research in STEM fields. For more information, contact the Undergraduate Research Program at: urp

  15. GRADUATE PROGRAM UNDERGRADUATE PROGRAMS

    E-print Network

    SELF STUDY GRADUATE PROGRAM UNDERGRADUATE PROGRAMS DEPARTMENT OF POLITICAL SCIENCE COLLEGE OF LIBERALARTS TEXAS A&M UNIVERSITY March 2007 #12;SELF STUDY GRADUATE PROGRAM UNDERGRADUATE PROGRAMS DEPARTMENT........................................................................................ 4 Brief History of Degree Programs and the Department

  16. Undergraduate TA's in Big Courses--Everybody Wins.

    ERIC Educational Resources Information Center

    Hazeltine, Barrett

    1981-01-01

    Describes the use of undergraduate teaching assistants in electronic circuits and engineering management courses. Teaching assistants guide discussions and assist in laboratory exercises. Requirements for using teaching assistants effectively, benefits to teaching assistants, and possible problems are also discussed. (DS)

  17. Minor in Chemistry 1. A Chemistry Minor is achieved by taking courses with a "CHEM" label. Biochemistry ("BCHM")

    E-print Network

    New Hampshire, University of

    Minor in Chemistry 1. A Chemistry Minor is achieved by taking courses with a "CHEM" label. Biochemistry ("BCHM") courses do not count toward a Chemistry Minor. The following CHEM courses in Chemistry unless you have completed Physical Chemistry 1 (Chem 683) and the accompanying laboratory course

  18. Two-Dimensional Nuclear Magnetic Resonance Structure Determination Module for Introductory Biochemistry: Synthesis and Structural Characterization of Lyso-Glycerophospholipids

    ERIC Educational Resources Information Center

    Garrett, Teresa A.; Rose, Rebecca L.; Bell, Sidney M.

    2013-01-01

    In this laboratory module, introductory biochemistry students are exposed to two-dimensional [superscript 1]H-nuclear magnetic resonance of glycerophospholipids (GPLs). Working in groups of three, students enzymatically synthesized and purified a variety of 2-acyl lyso GPLs. The structure of the 2-acyl lyso GPL was verified using [superscript…

  19. Undergraduate Advising Handbook

    E-print Network

    Undergraduate Advising Handbook 2011-2012 Undergraduate Program 201 More Hall Box 352700 Seattle to ensure pro- gress towards their degree. CEE Advising Handbook 2011-12 v1. Adopted from previous departmental handbooks. Questions? Contact CEE undergraduate advisor, Mariko Navin, at ceavice@uw.edu, or 206

  20. Undergraduate Advising Handbook

    E-print Network

    Undergraduate Advising Handbook 2010-2011 Undergraduate Program 201 More Hall Box 352700 Seattle to ensure progress towards their degree. CEE Advising Handbook 2010-11 v1. Adopted from previous departmental handbooks. Questions? Contact CEE undergraduate advisor, Mariko Navin, at ceavice@uw.edu, or 206

  1. Using an international p53 mutation database as a foundation for an online laboratory in an upper level undergraduate biology class.

    PubMed

    Melloy, Patricia G

    2015-01-01

    A two-part laboratory exercise was developed to enhance classroom instruction on the significance of p53 mutations in cancer development. Students were asked to mine key information from an international database of p53 genetic changes related to cancer, the IARC TP53 database. Using this database, students designed several data mining activities to look at the changes in the p53 gene from a number of perspectives, including potential cancer-causing agents leading to particular changes and the prevalence of certain p53 variations in certain cancers. In addition, students gained a global perspective on cancer prevalence in different parts of the world. Students learned how to use the database in the first part of the exercise, and then used that knowledge to search particular cancers and cancer-causing agents of their choosing in the second part of the exercise. Students also connected the information gathered from the p53 exercise to a previous laboratory exercise looking at risk factors for cancer development. The goal of the experience was to increase student knowledge of the link between p53 genetic variation and cancer. Students also were able to walk a similar path through the website as a cancer researcher using the database to enhance bench work-based experiments with complementary large-scale database p53 variation information. PMID:25395068

  2. Journal of Undergraduate Research, Volume IX, 2009

    SciTech Connect

    Stiner, K. S.; Graham, S.; Khan, M.; Dilks, J.; Mayer, D.

    2009-01-01

    Each year more than 600 undergraduate students are awarded paid internships at the Department of Energy’s (DOE) National Laboratories. Th ese interns are paired with research scientists who serve as mentors in authentic research projects. All participants write a research abstract and present at a poster session and/or complete a fulllength research paper. Abstracts and selected papers from our 2007–2008 interns that represent the breadth and depth of undergraduate research performed each year at our National Laboratories are published here in the Journal of Undergraduate Research. The fields in which these students worked included: Biology; Chemistry; Computer Science; Engineering; Environmental Science; General Science; Materials Science; Medical and Health Sciences; Nuclear Science; Physics; Science Policy; and Waste Management.

  3. Biochemistry Online: An Approach Based on Chemical Logic

    NSDL National Science Digital Library

    Dr Henry Jakubowski

    This is an interactive web-based biochemistry text that I created for my upper division biochemistry class over the past five years. The book - Biochemistry Online: An Approach Basedon Chemical Logic - is based on a unique sequencing and approach to a one semester, or the first of a two semester, biochemistry course. I have published a manuscript describing this new approach. (Jakubowski, H. and Owen, W.G. The Teaching of Biochemistry: An Innovative Course Sequence Based on the Logic of Chemistry, Journal of Chemical Education, 75, 734-736, 1998).

  4. Final Project Biochemistry 218 Computational Molecular Biology

    E-print Network

    of the Human Genome Project in 2003 and the International HapMap Project in 2007 have enabled finding genomicFinal Project Biochemistry 218 Computational Molecular Biology Jong Lee Recent Advances in Statistical Methods for Genome-Wide Association Studies - How do we distinguish a needle from a string of hay

  5. Updated September 2012 Biochemistry Degree Requirements

    E-print Network

    Cina, Jeff

    & Spectroscopy CH 441 Inorganic Chemistry Lab CH 437 Physical Biochemistry CH 465 Molecular Genetics of Human BI 466 Human Molecular Genetics BI 423 Developmental Genetics of Cancer BI 426 Advanced Molecular Genetics BI 424 Developmental Genetics BI 428 Genomic Appl. and Analysis BI 493 Protein Toxins in Cell

  6. The Physiology and Biochemistry of Receptors.

    ERIC Educational Resources Information Center

    Spitzer, Judy A., Ed.

    1983-01-01

    The syllabus for a refresher course on the physiology and biochemistry of receptors (presented at the 1983 American Physiological Society meeting) is provided. Topics considered include receptor regulation, structural/functional aspects of receptors for insulin and insulin-like growth factors, calcium channel inhibitors, and role of lipoprotein…

  7. Integrated Laboratories: Crossing Traditional Boundaries

    ERIC Educational Resources Information Center

    Dillner, Debra K.; Ferrante, Robert F.; Fitzgerald, Jeffrey P.; Heuer, William B.; Schroeder, Maria J.

    2007-01-01

    A new, integrated laboratory curriculum was recently developed at the U.S. Naval Academy in response to the 1999 ACS Committee on Professional Training guidelines that required inclusion of biochemistry and a stronger emphasis on student research. To meet these ACS requirements and to introduce more student choice in the major, we embarked on a…

  8. Obsidian Hydration Dating in the Undergraduate Curriculum.

    ERIC Educational Resources Information Center

    Manche, Emanuel P.; Lakatos, Stephen

    1986-01-01

    Provides an overview of obsidian hydration dating for the instructor by presenting: (1) principles of the method; (2) procedures; (3) applications; and (4) limitations. The theory of the method and one or more laboratory exercises can be easily introduced into the undergraduate geology curriculum. (JN)

  9. Efficient Optoelectronics Teaching in Undergraduate Engineering Curriculum

    ERIC Educational Resources Information Center

    Matin, M. A.

    2005-01-01

    The Engineering Department's vision for undergraduate education for the next century is to develop a set of laboratory experiences that are thoughtfully sequenced and integrated to promote the full development of students in all courses. Optoelectronics is one of the most important and most demanding courses in Electrical and Computer Engineering.…

  10. Centrifugal Pump Experiment for Chemical Engineering Undergraduates

    ERIC Educational Resources Information Center

    Vanderslice, Nicholas; Oberto, Richard; Marrero, Thomas R.

    2012-01-01

    The purpose of this paper is to describe a Centrifugal Pump Experiment that provided an experiential learning experience to chemical engineering undergraduates at the University of Missouri in the spring of 2010 in the Unit Operations Laboratory course. Lab equipment was used by senior students with computer-based data and control technology. In…

  11. NMR of a Phospholipid: Modules for Advanced Laboratory Courses

    NASA Astrophysics Data System (ADS)

    Gaede, Holly C.; Stark, Ruth E.

    2001-09-01

    A laboratory project is described that builds upon the NMR experience undergraduates receive in organic chemistry with a battery of NMR experiments that investigate egg phosphatidylcholine (egg PC). This material, often labeled in health food stores as lecithin, is a major constituent of mammalian cell membranes. The NMR experiments may be used to make resonance assignments, to study molecular organization in model membranes, to test the effects of instrumental parameters, and to investigate the physics of nuclear spin systems. A suite of modular NMR exercises is described, so that the instructor may tailor the laboratory sessions to biochemistry, instrumental analysis, or physical chemistry. The experiments include solution-state one-dimensional (1D) 1H, 13C, and 31P experiments; two-dimensional (2D) TOtal Correlated SpectroscopY (TOCSY); and the spectral editing technique of Distortionless Enhancement by Polarization Transfer (DEPT). To demonstrate the differences between solution and solid-state NMR spectroscopy and instrumentation, a second set of experiments generates 1H, 13C, and 31P spectra of egg PC dispersed in aqueous solution, under both static and magic-angle spinning conditions.

  12. Dr. Ivano Tavernelli Laboratory of Computational Chemistry and Biochemistry

    E-print Network

    Cuendet, Michel

    CM0702 on "Chemistry with Ultrafast Pulses and Free-Electron Lasers: Looking for Control Strategies: "Chemistry With Ultrashort Pulses and Free-Electron Lasers: Looking for Control Strategies Through "Exact

  13. Otumoetai Trust Undergraduate Scholarships OTUMOETAI TRUST UNDERGRADUATE SCHOLARSHIPS REGULATIONS FOR

    E-print Network

    Waikato, University of

    Otumoetai Trust Undergraduate Scholarships OTUMOETAI TRUST UNDERGRADUATE SCHOLARSHIPS REGULATIONS FOR 2009 BACKGROUND The Otumoetai Trust Undergraduate Scholarship was established in 1998 with the first scholarships awarded for 1999. REGULATIONS 1. The Scholarships shall be known as the Otumoetai Trust

  14. Biochemistry (Moscow): Telomere, Telomerase, Cancer, and Aging

    NSDL National Science Digital Library

    This Special Issue of Biochemistry (Moscow), (Volume 62 (1997), Number 11) includes several technical review articles on telomere, telomerase, cancer and aging. There has been a recent finding regarding telomerase, a gene which affects the mechanisms controlling human cell replication. The site above provides general information on telomerase, current telomere research, and the use of telemorase in medical practice. Telomerase increases the life-span of a cell, and is thus central to both aging and cancer.

  15. Glucosinolates – biochemistry, genetics and biological activity

    Microsoft Academic Search

    Richard Mithen

    2001-01-01

    This paper provides a brief overview of the biochemistry, genetics andbiological activity of glucosinolates and their degradation products.These compounds are found in vegetative and reproductive tissues of16 plant families, but are most well known as the major secondarymetabolites in the Brassicaceae. Following tissue disruption, theyare hydrolysed to a variety of products of which isothiocyanates(`mustard oils') are the most prominent. The

  16. University Handbook Undergraduate Advisors

    E-print Network

    Dobbins, Ian G.

    Undergraduate: College of Architecture ............................................16 College of Art.........................................................17 College of Arts & Sciences.........................................18 School of Business............................................23 Occupational Therapy: MOT.......................................24 Physical Therapy: DPT

  17. National Undergraduate Research Observatory

    NSDL National Science Digital Library

    The National Undergraduate Research Observatory (NURO) at Northern Arizona University and Lowell Observatory "is a consortium of primarily undergraduate institutions which have joined together to provide hands-on training and research experiences for undergraduate students." While the Key Projects link is under construction, users can find out about past student projects at the Undergraduate Research Experiences link. Researchers and students can request observation time and find planning and observing information. The website offers an image gallery and links to the consortium's member schools.

  18. 10/13/08 DSE/BMB AY08/09 Biochemistry and Molecular Biology

    E-print Network

    Chapman, Michael S.

    10/13/08 DSE/BMB AY08/09 Biochemistry and Molecular Biology Division of Environmental-2009 Degree: Biochemistry and Molecular Biology ­ Master of Science ­ Nonthesis...........................2 Track: Biochemistry and Molecular Biology

  19. SCHOOL OF CHEMISTRY AND BIOCHEMISTRY GEORGIA INSTITUTE OF TECHNOLOGY

    E-print Network

    Houston, Paul L.

    SCHOOL OF CHEMISTRY AND BIOCHEMISTRY GEORGIA INSTITUTE OF TECHNOLOGY EXIT CLEARANCE for Graduate) __________________ Teaching assistant book/manuals/supplied (TA supervisor) __________________ Exit interview (Lawrence

  20. ERA-experiment "Space Biochemistry".

    PubMed

    Dose, K; Bieger-Dose, A; Dillmann, R; Gill, M; Kerz, O; Klein, A; Meinert, H; Nawroth, T; Risi, S; Stridde, C

    1995-01-01

    The general goal of the experiment was to study the response of anhydrobiotic (metabolically dormant) microorganisms (spores of Bacillus subtilis, cells of Deinococcus radiodurans, conidia of Aspergillus species) and cellular constituents (plasmid DNA, proteins, purple membranes, amino acids, urea) to the extremely dehydrating conditions of open space, in some cases in combination with irradiation by solar UV-light. Methods of investigation included viability tests, analysis of DNA damages (strand breaks, DNA-protein cross-links) and analysis of chemical effects by spectroscopic, electrophoretic and chromatographic methods. The decrease in viability of the microorganisms was as expected from simulation experiments in the laboratory. Accordingly, it could be correlated with the increase in DNA damages. The purple membranes, amino acids and urea were not measurably effected by the dehydrating condition of open space (in the dark). Plasmid DNA, however, suffered a significant amount of strand breaks under these conditions. The response of these biomolecules to high fluences of short wavelength solar UV-light is very complex. Only a brief survey can be given in this paper. The data on the relatively good survival of some of the microorganisms call for strict observance of COSPAR Planetary Protection Regulations during interplanetary space missions. PMID:11542696

  1. Designing Effective Undergraduate Research Experiences

    NASA Astrophysics Data System (ADS)

    Severson, S.

    2010-12-01

    I present a model for designing student research internships that is informed by the best practices of the Center for Adaptive Optics (CfAO) Professional Development Program. The dual strands of the CfAO education program include: the preparation of early-career scientists and engineers in effective teaching; and changing the learning experiences of students (e.g., undergraduate interns) through inquiry-based "teaching laboratories." This paper will focus on the carry-over of these ideas into the design of laboratory research internships such as the CfAO Mainland internship program as well as NSF REU (Research Experiences for Undergraduates) and senior-thesis or "capstone" research programs. Key ideas in maximizing student learning outcomes and generating productive research during internships include: defining explicit content, scientific process, and attitudinal goals for the project; assessment of student prior knowledge and experience, then following up with formative assessment throughout the project; setting reasonable goals with timetables and addressing motivation; and giving students ownership of the research by implementing aspects of the inquiry process within the internship.

  2. The Undergraduate Teaching Assistant Experience Offers Opportunities Similar to the Undergraduate Research Experience†

    PubMed Central

    Schalk, Kelly A.; McGinnis, J. Randy; Harring, Jeffrey R.; Hendrickson, Amy; Smith, Ann C.

    2009-01-01

    There has been a growing concern in higher education about our failure to produce scientifically trained workers and scientifically literate citizens. Active-learning and research-oriented activities are posited as ways to give students a deeper understanding of science. We report on an undergraduate teaching assistant (UTA) experience and suggest that students who participate as a UTA obtain benefits analogous to those who participate as an undergraduate research assistant (URA). We examined the experiences of 24 undergraduates acting as UTAs in a general microbiology course. Self-reported gains by the UTAs were supported by observational data from undergraduates in the course who were mentored by the UTAs and by the graduate teaching assistants (GTAs) with whom the UTAs worked. Specifically, data from the UTAs’ journals and self-reported Likert scales and rubrics indicated that our teaching assistants developed professional characteristics such as self-confidence and communication and leadership skills, while they acquired knowledge of microbiology content and laboratory skills. Data from the undergraduate Likert scale as well as the pre- and post-GTA rubrics further confirmed our UTA’s data interpretations. These findings are significant because they offer empirical data to support the suggestion that the UTA experience is an effective option for developing skills and knowledge in undergraduates that are essential for careers in science. The UTA experience provides a valuable alternative to the URA experience. PMID:23653688

  3. An Introductory Undergraduate Course Covering Animal Cell Culture Techniques

    ERIC Educational Resources Information Center

    Mozdziak, Paul E.; Petitte, James N.; Carson, Susan D.

    2004-01-01

    Animal cell culture is a core laboratory technique in many molecular biology, developmental biology, and biotechnology laboratories. Cell culture is a relatively old technique that has been sparingly taught at the undergraduate level. The traditional methodology for acquiring cell culture training has been through trial and error, instruction when…

  4. 2012UNDERGRADUATE SCHOLARSHIPS

    E-print Network

    2012UNDERGRADUATE SCHOLARSHIPS #12;The University's scholarships website at www.adelaide. edu.au/scholarships of scholarships for undergraduate and Honours students studying at the University. #12;Commencing Students engineering in a Commonwealth-supported place. The Andy Thomas Scholarship is available to Australian citizens

  5. UNDERGRADUATE Published by

    E-print Network

    1100 Undergraduate Scholarships and Prizes T: 02 6125 5595 Enquiries All enquiries should be addressed2007 UNDERGRADUATE HANDBOOK #12;Published by The Australian National University Produced and the Pacific 347 Chapter 4 ANU College of Business and Economics 415 Chapter 5 ANU College of Engineering

  6. UNDERGRADUATE Political Science

    E-print Network

    Oyet, Alwell

    UNDERGRADUATE HANDBOOK Political Science Memorial University mun.ca/posc #12;UNDERGRADUATE STUDENT HANDBOOK Reflects Renewed Curriculum Effective Academic Year 2010-11 Department of Political Science Room). Prepared by Political Science students and the Department for Political Science students, with special

  7. CURRICULUM SUPPLEMENT UNDERGRADUATE CATALOG

    E-print Network

    Rosen, Jay

    a tuition waiver. August 30-31 Sat.-Sun. College Closed. September 1 Monday College Closed. September 3, and changes in degree requirements implemented by the College since the printing of the Undergraduate Catalog-2009 Undergraduate Catalog. COLLEGE OF STATEN ISLAND THE CITY UNIVERSITY OF NEW YORK #12;2 College Calendar

  8. Environmental Sciences Undergraduate Program

    E-print Network

    Kurapov, Alexander

    Environmental Sciences Undergraduate Program Ecampus Advising Guide Revised 08/24/12 20122013 #12;Page 2 of 29 | Rev. 08/24/12 Environmental Sciences Undergraduate Program: A Hands reach these objectives, Oregon State University's Environmental Sciences Bachelor of Sciences degree

  9. Undergraduate Advising Handbook

    E-print Network

    Undergraduate Advising Handbook 2013-2014 Undergraduate Program 201 More Hall Box 352700 Seattle to ensure pro- gress towards their degree. CEE Advising Handbook 2013-14 v1. Questions? Contact CEE Handbook is intended as a resource to help you familiarize yourself with the BSCE program, our depart- ment

  10. Mechanical Engineering Undergraduate

    E-print Network

    Ghosh, Somnath

    Mechanical Engineering Department Undergraduate Advising Manual for Bachelor of Science Degrees in Mechanical Engineering and Engineering Mechanics 2011-2012 - Updated April 15, 2012 #12;Johns Hopkins University ­ Department of Mechanical Engineering 2011-2012 Undergraduate Student Advising Manual Page 2

  11. Mechanical Engineering Undergraduate

    E-print Network

    Ghosh, Somnath

    Mechanical Engineering Department Undergraduate Advising Manual for Bachelor of Science Degrees in Mechanical Engineering and Engineering Mechanics 2012-2013 - Updated July 14, 2013 #12;Johns Hopkins University ­ Department of Mechanical Engineering 2012-2013 Undergraduate Student Advising Manual Page 2

  12. A New Paradigm for Mentored Undergraduate Research in Molecular Microbiology

    PubMed Central

    2007-01-01

    Science educators agree that an undergraduate research experience is critical for students who are considering graduate school or research careers. The process of researching a topic in the primary literature, designing experiments, implementing those experiments, and analyzing the results is essential in developing the analytical skills necessary to become a true scientist. Because training undergraduates who will only be in the laboratory for a short period is time consuming for faculty mentors, many students are unable to find appropriate research opportunities. We hypothesized that we could effectively mentor several students simultaneously, using a method that is a hybrid of traditional undergraduate research and a traditional laboratory course. This article describes a paradigm for mentored undergraduate research in molecular microbiology where students have ownership of their individual projects, but the projects are done in parallel, enabling the faculty mentor to guide multiple students efficiently. PMID:18056305

  13. Cardiovascular Simulator for the Undergraduate Physics Laboratory.

    ERIC Educational Resources Information Center

    Bruner, L. J.

    1979-01-01

    Described is a cardiovascular simulator which illustrates the use of a catheter-coupled external transducer for dynamic pressure measurements in the circulatory system. With the simulator, students can observe the effects of stroke volume and rate upon maximum, minimum, and mean arterial pressure. (Author/GA)

  14. EDITORIAL: Student undergraduate laboratory and project work

    Microsoft Academic Search

    Dieter Schumacher

    2007-01-01

    During the last decade 'labwork' courses at university level have changed significantly. The beginning of this development was indicated and partly initiated by the EU-project 'Labwork in Science Education' funded by the European Community (1999-2001). The present special issue of the European Journal of Physics focuses on a multitude of different aspects of this process. The aim of this publication

  15. Materials Laboratory Classes for First Year Undergraduates

    ERIC Educational Resources Information Center

    Fahy, F. W.

    1975-01-01

    Describes a combined demonstration and student experiment course to illustrate fundamental techniques, instrumentation, and concise report writing. Describes experiments including tensile tests, heat treatment, equilibrium diagram, microexamination, strain measurement, and recrystallization. (GH)

  16. Hematology for Undergraduates

    ERIC Educational Resources Information Center

    Navari, Rudolph M.

    1972-01-01

    Describes a five-week introductory medical science course designed for both science and nonscience majors through integration of physiology, organic chemistry, anatomy, and biochemistry. Suggests its use as a quarter-semester, a tri-semester, or a regular semester course for students including premed and medical technicians. (CC)

  17. Department name Undergraduate

    E-print Network

    Sheldon, Nathan D.

    · A broad portfolio of bursaries and scholarships Why choose Royal Holloway #12;2 #12;Welcome to Royal and scholarships 29 An international community 30 Student support 32 Information services 34 Postgraduate study 36 of History & Social Sciences 58 Faculty of Science 60 Biochemistry 62 Biology 64 Biomedical Sciences 66

  18. CALENDAR 2010-2011 Undergraduate

    E-print Network

    Barthelat, Francois

    UNIVERSITY CALENDAR 2010-2011 Undergraduate Scholarships and Awards #12;McGill University, Undergraduate Scholarships and Awards 2010-2011 1 About This Calendar Published by Enrolment Services Mc Design #12;#12;McGill University, Undergraduate Scholarships and Awards 2010-2011 3 Undergraduate

  19. Clique-detection Models in Computational Biochemistry and Genomics

    E-print Network

    Butenko, Sergiy

    Clique-detection Models in Computational Biochemistry and Genomics S. Butenko and W. E. Wilhelm,wilhelm}@tamu.edu Abstract Many important problems arising in computational biochemistry and genomics have been formulated and genomic aspects of the problems as well as to the graph-theoretic aspects of the solution approaches. Each

  20. Mississippi State University 1 Department of Biochemistry, Molecular Biology,

    E-print Network

    Ray, David

    Mississippi State University 1 Department of Biochemistry, Molecular Biology, Entomology and Plant and Molecular Biology Program The Biochemistry and Molecular Biology program within the Department of BCH-EPP involves disciplines at the cutting edge of a revolution in biology. Molecular methods and the use

  1. COURSE TITLE and NUMBER: Medical Biochemistry (Fall Semester 2013)

    E-print Network

    Pres John L. Wang Jana Simmons 224A Biochemistry 402D Biochemistry 617 Secchia (517) 432-9282 (517) 353, October 18 Noon - 1:00 pm 11 am - noon Noon ­ 1:00 pm 10 am ­ noon 12 noon - 1 pm Simmons Simmons Simmons Simmons Simmons 120 Secchia 120 Secchia 120 Secchia 120 Secchia 120 Secchia Course Objectives: This course

  2. Self-Study Report Department of Biochemistry and Biophysics

    E-print Network

    Polymenis Ry Young #12;2 Executive Summary This report describes the state of the Department of BiochemistrySelf-Study Report Department of Biochemistry and Biophysics External Academic Program Review, April by the department require independent research, this review necessarily includes coverage of the research

  3. Biochemistry 766: Nucleic Acids http://carmen.osu.edu

    E-print Network

    Foster, Mark P.

    Biochemistry 766: Nucleic Acids http://carmen.osu.edu Winter Quarter 2011, 3 cr., Course No. 6738, or by appointment Primary Text: Nucleic Acids in Chemistry and Biology. Blackburn, Gait, Loakes and Williams, eds Nucleic acids biochemistry; history and context Nucleic acid nomenclature; tautomerism; ionization

  4. Commentary: Biochemistry and Molecular Biology Educators Launch National Network

    ERIC Educational Resources Information Center

    Bailey, Cheryl; Bell, Ellis; Johnson, Margaret; Mattos, Carla; Sears, Duane; White, Harold B.

    2010-01-01

    The American Society of Biochemistry and Molecular Biology (ASBMB) has launched an National Science Foundation (NSF)-funded 5 year project to support biochemistry and molecular biology educators learning what and how students learn. As a part of this initiative, hundreds of life scientists will plan and develop a rich central resource for…

  5. The biochemistry of disease: desperately seeking syzygy.

    PubMed

    Kozarich, John W

    2009-01-01

    The elucidation of the precise molecular structure and dynamics of biological processes is the great work of biochemistry. From this, insights into the changes leading to process dysfunction or disease are derived, as well as the possible approaches to restore healthy function. Translating this information into effective and safe treatments for disease requires a coordinated interdisciplinary effort, a fusion of creativity and practicality, and a healthy dose of luck. Using several reviews in this volume as springboards, I discuss the broader issues of drug development, highlighting some recent successes and future directions. Such occurrences inspire awe but remain too rare for comfort. PMID:19489721

  6. Chemistry and Biochemistry of Dietary Polyphenols

    PubMed Central

    Tsao, Rong

    2010-01-01

    Polyphenols are the biggest group of phytochemicals, and many of them have been found in plant-based foods. Polyphenol-rich diets have been linked to many health benefits. This paper is intended to review the chemistry and biochemistry of polyphenols as related to classification, extraction, separation and analytical methods, their occurrence and biosynthesis in plants, and the biological activities and implications in human health. The discussions are focused on important and most recent advances in the above aspects, and challenges are identified for future research. PMID:22254006

  7. Adapting a Biochemistry Course to Distance Education

    ERIC Educational Resources Information Center

    Yokaichiya, Daniela K.; Galembeck, Eduardo; Torres, Bayardo B.

    2004-01-01

    Internet-based distance education seems to be an attractive alternative to offer courses dealing with specific topics that are not conveniently explored in undergraduate courses. This is a good way to provide access to the recent and updated discoveries in this research area and to reach people who could not take the classes in the traditional…

  8. A Laboratory Safety Trivia Game

    Microsoft Academic Search

    Kristin I. Gublo

    2003-01-01

    At the start of each semester, our department begins our chemistry seminar series with a presentation on laboratory safety. All chemistry faculty, staff, graduate students, undergraduate research students, and student laboratory assistants are required to attend. Many of these individuals have sat through these seminars for several years; they feel the seminars are boring and repetitive. In order to enliven

  9. Undergraduate Research Sponsored by the

    E-print Network

    Engel, Robert

    , Dr. John Dennehy, Biology "Testing the Fitness of Bacteriophage 6 Mutants on both its original and Biochemistry "Development of a One-pot Palladium-Catalyzed Synthesis of Isoquinoline Scaffolds" 2:30 pm Xhesika Shanja, Yu Chen, Chemistry and Biochemistry "One-Pot Synthesis of Isoxazoles by Palladium

  10. NANOLAB at The University of Texas at Austin: A Model for Interdisciplinary Undergraduate Science and Engineering Education

    ERIC Educational Resources Information Center

    Heitsch, Andrew T.; Ekerdt, John G.; Korgel, Brian A.

    2009-01-01

    The University of Texas at Austin has developed an upper-division undergraduate laboratory called "NANOLAB" to introduce undergraduate science and engineering students to nanoscale science and engineering (NSE) concepts. The NANOLAB is not a stand-alone course offered by a specific department, but rather a laboratory station--or hub--that…

  11. Quantum Mechanics II (Undergraduate)

    E-print Network

    Nickrent, Daniel L.

    Quantum Mechanics II (Undergraduate) Applications of Quantum Mechanics Spring, 2014 Physics 440 TEXTBOOK: Introduction to Quantum Mechanics (Second Edition), by David J. Griffiths, and QUNET's wikibook to apply quantum mechanics to some fundamental and important problems such as: better understanding

  12. Carnegie Mellon Undergraduate Catalog

    E-print Network

    Carnegie Mellon University Undergraduate Catalog 2008­2010 Carnegie Institute of Technology the Carnegie Mellon Police Department at 412- 268-2323. The security report is also available online. Obtain Offered 12 Carnegie Institute of Technology

  13. HANDBOOK FOR UNDERGRADUATE

    E-print Network

    Gaucher, Eric

    1 HANDBOOK FOR UNDERGRADUATE STUDENTS SCHOOL OF BIOLOGY 2012 - 2013 #12;2 TABLE OF CONTENTS ................................................................................................................... 3 The Long-term Goal: What to do with a B.S. in Biology Biology Minor and Certificate Programs

  14. Research Experiences for Undergraduates.

    ERIC Educational Resources Information Center

    Rettig, Terrence W.; And Others

    1990-01-01

    Reviewed are six programs at different colleges and universities which provide research opportunities for undergraduate students in physics, astronomy, marine biology, meteorology, and anthropology. Background, features, and accomplishments of the programs are discussed. (CW)

  15. college of engineering Undergraduate

    E-print Network

    college of engineering FACT SHEET Undergraduate » Bioengineering » chemical engineering » civil » energy Systems engineering The College of Engineering at Oregon State University delivers impactful » Biological and ecological engineering » chemical engineering » civil engineering » computer Science

  16. college of engineering Undergraduate

    E-print Network

    Tullos, Desiree

    college of engineering FACT SHEET Undergraduate » Bioengineering » chemical engineering » civil » computer Science » energy Systems engineering The College of Engineering at Oregon State University. Graduate » Biological and ecological engineering » chemical engineering » civil engineering » computer

  17. Academic Majors Undergraduate Majors

    E-print Network

    Weston, Ken

    Department of Nutrition, Food and Exercise Sciences Aging/Cancer · Body Composition · Cardiovascular HealthAcademic Majors Undergraduate Majors Food & Nutrition Sciences Dietetics Exercise Science Athletic Training Masters Majors Nutrition & Food Sciences Exercise Physiology Sports Sciences Doctoral Majors

  18. UNDERGRADUATE SCHOLARSHIPS WITH

    E-print Network

    Hu, Wen-Chen

    RESEARCH Biology, Chemistry, Geography and Mathematics Types of Scholarships: Financial support for upUS MASTER UNDERGRADUATE SCHOLARSHIPS WITH MATHEMATICS AND SCIENCE TRAINING IN ENVIRONMENTAL. Students will be advised by the faculty performing actual research in the area. Biology projects

  19. Student Handbook Undergraduate Education

    E-print Network

    Hemmers, Oliver

    Student Handbook Undergraduate Education College of Education University of Nevada, Las Vegas #12;College of Education, Student Handbook Page Handbook Page 2 ABOUT THE COLLEGE The College of Education (COE

  20. MECHANICAL ENGINEERING UNDERGRADUATE MAJOR

    E-print Network

    HANDBOOK FOR MECHANICAL ENGINEERING UNDERGRADUATE MAJOR Old Dominion University Department of Mechanical Engineering Batten College of Engineering and Technology Norfolk, Virginia 23529-0247 #12;TABLE OF CONTENTS MECHANICAL ENGINEERING HANDBOOK

  1. for Undergraduate CHEMISTRY MAJORS

    E-print Network

    Stuart, Steven J.

    and Petroleum Chemistry, Organic Chemistry, Physical Chemistry, Polymer Chemistry, Pulp and Paper Chemistry, RHANDBOOK for Undergraduate CHEMISTRY MAJORS DEPARTMENT OF CHEMISTRY Fall 2010 #12;#12;TABLE OF CONTENTS A Career in Chemistry - What It Means ___________________________________________ 4 What do

  2. Journal of Undergraduate Research, Volume I, 2001

    SciTech Connect

    Faletra, P.; Beavis, W.; Franz, K.; Musick, C.; Walbridge, S.E.; Myron, H.

    2001-01-01

    This is our first volume of the Undergraduate Journal. It is an approbation of the impressive research performed by summer interns under the guidance of their dedicated mentors. The full-length publications were chosen from a pool of submissions that were reviewed by many of the excellent scientists at our National Laboratories. Most of these students will pursue careers in science, engineering and technology and, hopefully, some of this talent will remain with our labs. We have also included about 125 abstracts that survived the review process. These were submitted from all of our participating National Laboratories.

  3. Egg Yolk Lecithin: A Biochemical Laboratory Project

    ERIC Educational Resources Information Center

    White, Bernard J.; And Others

    1974-01-01

    Describes an undergraduate laboratory project involving lecithin which integrates two general aspects of lipid methodology: chromatographic techniques and use of enzymes specificity to obtain structural information. (Author/SLH)

  4. Development of an Undergraduate Course--Internet-Based Instrumentation and Control

    ERIC Educational Resources Information Center

    Zhuang, Hanqi; Morgera, Salvatore D.

    2007-01-01

    The objective, strategy, and implementation details of a new undergraduate course, Internet-based Instrumentation and Control, are presented. The course has a companion laboratory that is supported by the National Science Foundation and industry. The combination is offered to senior-level undergraduate engineering students interested in sensing,…

  5. Promoting Chemistry Learning through Undergraduate Work Experience in the Chemistry Lab: A Practical Approach

    ERIC Educational Resources Information Center

    Yu, Hong-Bin

    2015-01-01

    Hiring undergraduate lab assistants in chemistry departments is common in college. However, few studies have focused on promoting undergraduate chemistry learning and thinking skills through this work experience in chemistry teaching laboratories. This article discusses the strategy we implemented in the lab assistant program. The…

  6. A Safer and Convenient Synthesis of Sulfathiazole for Undergraduate Organic and Medicinal Chemistry Classes

    ERIC Educational Resources Information Center

    Boyle, Jeff; Otty, Sandra; Sarojini, Vijayalekshmi

    2012-01-01

    A safer method for the synthesis of the sulfonamide drug sulfathiazole, for undergraduate classes, is described. This method improves upon procedures currently followed in several undergraduate teaching laboratories for the synthesis of sulfathiazole. Key features of this procedure include the total exclusion of pyridine, which has potential…

  7. Engaging Undergraduates in Social Science Research: The Taking the Pulse of Saskatchewan Project

    ERIC Educational Resources Information Center

    Berdahl, Loleen

    2014-01-01

    Although student involvement in research and inquiry can advance undergraduate learning, there are limited opportunities for undergraduate students to be directly involved in social science research. Social science faculty members typically work outside of laboratory settings, with the limited research assistance work being completed by graduate…

  8. Development of an undergraduate course - Internet-based instrumentation and control

    Microsoft Academic Search

    Hanqi Zhuang; Salvatore D. Morgera

    2007-01-01

    The objective, strategy, and implementation details of a new undergraduate course, Internet-based Instrumentation and Control, are presented. The course has a companion laboratory that is supported by the National Science Foundation and industry. The combination is offered to senior-level undergraduate engineering students interested in sensing, instrumentation, control, and web programming that want to learn more about the integration of these

  9. Mentoring Undergraduate Students in Neuroscience Research: A Model System at Baldwin-Wallace College

    NSDL National Science Digital Library

    G. Andrew Mickley, (Baldwin-Wallace College,; )

    2003-05-30

    This resource describes opportunities given to undergraduate students to become involved in a sustained, faculty-initiated research program. The system described here provides an encouraging structured community in which undergraduates can develop and mature as they are mentored in the context of a modern neuroscience laboratory.

  10. Juvenile hormone esterase: biochemistry and structure

    PubMed Central

    Kamita, Shizuo G.; Hammock, Bruce D.

    2013-01-01

    Synopsis Normal insect development requires a precisely timed, precipitous drop in hemolymph juvenile hormone (JH) titer. This drop occurs through a coordinated halt in JH biosynthesis and increase in JH metabolism. In many species, JH esterase (JHE) is critical for metabolism of the resonance-stabilized methyl ester of JH. JHE metabolizes JH with a high kcat/KM ratio that results primarily from an exceptionally low KM. Here we review the biochemistry and structure of authentic and recombinant JHEs from six insect orders, and present updated diagnostic criteria that help to distinguish JHEs from other carboxylesterases. The use of a JHE-encoding gene to improve the insecticidal efficacy of biopesticides is also discussed. PMID:23543805

  11. Role of tautomerism in RNA biochemistry

    PubMed Central

    Singh, Vipender; Fedeles, Bogdan I.

    2015-01-01

    Heterocyclic nucleic acid bases and their analogs can adopt multiple tautomeric forms due to the presence of multiple solvent-exchangeable protons. In DNA, spontaneous formation of minor tautomers has been speculated to contribute to mutagenic mispairings during DNA replication, whereas in RNA, minor tautomeric forms have been proposed to enhance the structural and functional diversity of RNA enzymes and aptamers. This review summarizes the role of tautomerism in RNA biochemistry, specifically focusing on the role of tautomerism in catalysis of small self-cleaving ribozymes and recognition of ligand analogs by riboswitches. Considering that the presence of multiple tautomers of nucleic acid bases is a rare occurrence, and that tautomers typically interconvert on a fast time scale, methods for studying rapid tautomerism in the context of nucleic acids under biologically relevant aqueous conditions are also discussed. PMID:25516996

  12. Soft lithography in biology and biochemistry.

    PubMed

    Whitesides, G M; Ostuni, E; Takayama, S; Jiang, X; Ingber, D E

    2001-01-01

    Soft lithography, a set of techniques for microfabrication, is based on printing and molding using elastomeric stamps with the patterns of interest in basrelief. As a technique for fabricating microstructures for biological applications, soft lithography overcomes many of the shortcomings of photolithography. In particular, soft lithography offers the ability to control the molecular structure of surfaces and to pattern the complex molecules relevant to biology, to fabricate channel structures appropriate for microfluidics, and to pattern and manipulate cells. For the relatively large feature sizes used in biology (> or = 50 microns), production of prototype patterns and structures is convenient, inexpensive, and rapid. Self-assembled monolayers of alkanethiolates on gold are particularly easy to pattern by soft lithography, and they provide exquisite control over surface biochemistry. PMID:11447067

  13. Transferrin: From Inorganic Biochemistry to Medicine

    PubMed Central

    Kratz, Felix

    1994-01-01

    Transferrin is one of the key proteins of iron metabolism in mammalians. It is responsible for the transfer of the essential iron(III) ions through the biological fluids from absorption to storage and utilization sites. Moreover, transferrin is involved in the metabolism of other metal ions that are either trace or toxic elements. In recent years the crystal structure of transferrin has been solved at high resolution. This has allowed an extensive reinterpretation of the many spectroscopic studies carried out on this protein in the last decade as well as the elucidation of some interesting structure-function relationships. We review here recent progresses in transferrin biochemistry, particular focus being given to those aspects that are relevant from a medical point of view. PMID:18476227

  14. Customized Laboratory Experience in Physical Chemistry

    ERIC Educational Resources Information Center

    Castle, Karen J.; Rink, Stephanie M.

    2010-01-01

    A new physical chemistry laboratory experience has been designed for upper-level undergraduate chemistry majors. Students customize the first 10 weeks of their laboratory experience by choosing their own set of experiments (from a manual of choices) and setting their own laboratory schedule. There are several topics presented in the accompanying…

  15. Communication, Communication, Communication! Growth through Laboratory Instructing

    ERIC Educational Resources Information Center

    Peterson, Jamie J.; DeAngelo, Samantha; Mack, Nancy; Thompson, Claudia; Cooper, Jennifer; Sesma, Arturo, Jr.

    2014-01-01

    This study examined gains undergraduate students made in their communication and collaboration skills when they served as peer teachers, i.e., laboratory instructors (LIs), for a General Psychology laboratory. Self-ratings of communication and collaboration skills were completed before and after teaching the laboratory. When compared to before the…

  16. History of Medical Laboratory Services in Bahrain. Part II. The Foundation of Modern Laboratory Services (1963-1975)

    Microsoft Academic Search

    F. Al Hilli

    In 1963, Dr George Inglott, a Maltese qualified Pathologist was recruited to be in charge of medical laboratory facilities, which lasted until 1975. He witnessed the foundation of modern laboratory clinical practice in Bahrain. He initially experienced limitations to advice on clinical practice of biochemistry and microbiology (including bacteriology, parasitology, and serology), but there were limited demands from the hospital

  17. Undergraduate research in geochemistry at a larger university: developing a community of undergraduate and graduate researchers.

    NASA Astrophysics Data System (ADS)

    Ryan, J. G.

    2003-12-01

    Faculty at state research universities can find the paired requirements of establishing research programs and developing a "pipeline" of graduate students to be the most challenging aspects of their jobs, especially with shrinking pools of graduate applicants. These problems may be more acute for laboratory-based geochemists, as few graduate candidates possess the requisite quantitative and chemical backgrounds. The need to "get my research going" at the University of South Florida led me to work primarily with undergraduates, as a) they were available and interested, b) they required no more laboratory training than M.S. students; and c) small-dollar funds were available to support them, both in-house and via NSF REU Supplements. Some senior colleagues argued that this approach would hinder my developing a graduate program as is necessary for tenure. This contention turned out to be untrue. My success in undergraduate research draws funding (in NSF REU Site and disciplinary research grants), has attracted outside MS and Ph.D. candidates, and has retained quality in-house students seeking MS degrees. Students working with me join a laboratory community in which undergraduate and graduate researchers are on equal footing in terms of access to instrumentation and other facilities. I work with all my students, irrespective of rank, as members of a cooperative research group. I encourage and expect that technical instruction I provide to any individual will be passed on to their colleagues, which helps develop a "lab culture" of best practices, and ingrains new knowledge and skills through the act of teaching them to others. Maintaining this research environment requires active recruitment of capable graduate AND undergraduate students, regular monitoring of laboratory practices, and ready availability for consultation and mentoring. One must be cognizant of the differing time commitment issues of undergraduates and graduates, and set research goals appropriately. Undergraduate research projects in which 3-4 students work together to collect necessary data can get around the class vs. research scheduling issues they face as they can share the laboratory workload through the week. Group projects can thus collect larger bodies of data, allowing students to address more substantive problems.

  18. Learning Goals for Major in Environmental Sciences Undergraduate Student Learning Initiative / University of California, Berkeley

    E-print Network

    Wildermuth, Mary C

    in environmental science. Senior Research Seminar and Laboratory in Environmental Sciences Environmental SciencesLearning Goals for Major in Environmental Sciences Undergraduate Student Learning Initiative / University of California, Berkeley Environmental Sciences (ES) is an interdisciplinary enterprise that deals

  19. Running an Undergraduate Research Conference

    Microsoft Academic Search

    James C. Squire; Matthew R. Hyre

    Independent research and design is a critical component of engineering education, yet undergraduates often have few opportunities to showcase their work. It can also be difficult to convey their experiences succinctly on a resume unless they publish or present their design. In order to provide a forum to communicate and celebrate undergraduate student achievement, many universities have created undergraduate research

  20. Conducting Mathematical Research with Undergraduates

    ERIC Educational Resources Information Center

    Roberts, Gareth E.

    2013-01-01

    The notion that undergraduates are capable of making profound and original contributions to mathematical research is rapidly gaining acceptance. Undergraduates bring their enthusiasm, creativity, curiosity, and perseverance to bona fide research problems. This article discusses some of the key issues concerning undergraduate mathematical research:…

  1. Undergraduate Handbook School of Law

    E-print Network

    Hickman, Mark

    Undergraduate Handbook School of Law Critique. LLB 2014LAW #12;Contents 1 From the Dean Welcome has been taken to ensure the information contained in this School of Law Undergraduate Handbook of Canterbury Calendar is definitive. School of Law Undergraduate Handbook published March 2014. 6 LLB

  2. Insulin Mediated 14C-Glucose Incorporation Into Adipose Tissue: An Undergraduate Biochemistry Experiment

    ERIC Educational Resources Information Center

    Landman, A. D.; Eskin, N. A. M.

    1975-01-01

    Describes an experiment in which rat adipose tissue samples are exposed to labeled glucose; insulin is added to one sample. Subsequent scintillation counting demonstrates the ability of insulin to facilitate the entry of glucose into the tissue. (MLH)

  3. A Versatile and Inexpensive Enzyme Purification Experiment for Undergraduate Biochemistry Labs.

    ERIC Educational Resources Information Center

    Farrell, Shawn O.; Choo, Darryl

    1989-01-01

    Develops an experiment that could be done in two- to three-hour blocks and does not rely on cold room procedures for most of the purification. Describes the materials, methods, and results of the purification of bovine heart lactate dehydrogenase using ammonium sulfate fractionation, dialysis, and separation using affinity chromatography and…

  4. Keeping a Laboratory Notebook

    NSDL National Science Digital Library

    The HURI SURI project is developing a regional biotechnology workforce pipeline by expanding and supporting biotechnology research experiences for Jamestown Community College (JCC) undergraduates and disseminating these research experiences and materials to area high school teachers and students. This Microsoft Word document details how to keep a laboratory notebook in a high school or undergraduate science class. This is important because "a laboratory notebook is really required by law for investigators that either work in an industry (e.g. pharmaceutical industry) that is federally regulated or for investigators who have federal grant funding for research (e.g. from the National Institutes of Health or National Science Foundation)." The document explains how the notebook needs a table of contents, experiment details, and conclusion.

  5. Integrating Undergraduate Students in Faculty-Driven Motor Behavior Research

    ERIC Educational Resources Information Center

    Robinson, Leah E.

    2013-01-01

    This article described the faculty-sponsored, faculty-driven approach to undergraduate research (UGR) at Auburn University. This approach is centered around research in the Pediatric Movement and Physical Activity Laboratory, and students can get elective course credit for their participation in UGR. The article also describes how students'…

  6. “Bioneering” – teaching biotechnology entrepreneurship at the undergraduate level

    Microsoft Academic Search

    Chris Collet; David Wyatt

    2005-01-01

    Purpose – The authors have developed an educational model that operates at the undergraduate level and aims to produce graduates who can comfortably operate in the gulf between the laboratory bench and the commercial marketplace. The purpose of the paper is to describe the course, approaches, activities and initial outcomes of the Bachelor of Biotechnology Innovation course at Queensland University

  7. Computer Based Data Acquisition in the Undergraduate Lab.

    ERIC Educational Resources Information Center

    Wepfer, William J.; Oehmke, Roger L. T.

    1987-01-01

    Describes a data acquisition system developed for an undergraduate engineering students' instructional laboratory at Georgia Tech. Special emphasis is placed on the design of an A/D Converter Board used to measure the viscosity and temperature of motor oil. The Simons' BASIC Program Listing for the Commodore 64 microcomputer is appended. (LRW)

  8. "Bioneering"--Teaching Biotechnology Entrepreneurship at the Undergraduate Level

    ERIC Educational Resources Information Center

    Collet, Chris; Wyatt, David

    2005-01-01

    Purpose - The authors have developed an educational model that operates at the undergraduate level and aims to produce graduates who can comfortably operate in the gulf between the laboratory bench and the commercial marketplace. The purpose of the paper is to describe the course, approaches, activities and initial outcomes of the Bachelor of…

  9. BIO2010: Transforming Undergraduate Education for Future Research Biologists

    ERIC Educational Resources Information Center

    National Academies Press, 2003

    2003-01-01

    The report discusses incorporating more math, physics, chemistry, engineering and computer science into classes and laboratory work and emphasizing independent research will help undergraduate education reflect real-world science. Schools, professional societies and funding agencies should develop new teaching materials and facilitate faculty…

  10. A Shack Interferometer Setup for Optical Testing in Undergraduate Courses

    ERIC Educational Resources Information Center

    Vannoni, Maurizio; Righini, Alberto; Salas, Matias; Sordini, Andrea; Vanzi, Leonardo

    2012-01-01

    The Shack interferometer is a simple and effective device to test optical surfaces in reflection and optical systems in transmission. An essential setup on a reduced scale with a minimum number of components is presented, suited to gain familiarity and practice with optical testing in a laboratory course for undergraduate students. The basic…

  11. A Methods-Based Biotechnology Course for Undergraduates

    ERIC Educational Resources Information Center

    Chakrabarti, Debopam

    2009-01-01

    This new course in biotechnology for upper division undergraduates provides a comprehensive overview of the process of drug discovery that is relevant to biopharmaceutical industry. The laboratory exercises train students in both cell-free and cell-based assays. Oral presentations by the students delve into recent progress in drug discovery.…

  12. Guide to Understanding Undergraduate

    E-print Network

    Massachusetts at Amherst, University of

    this guide to help you understand the components of your financial aid package as well as the options questions you may have regarding your financial aid award and financing options available for your college2012-2013 Guide to Understanding Undergraduate Financial Aid FINANCIAL AID SERVICES ACADEMIC

  13. Highlights of Undergraduate

    E-print Network

    to showcase some of the fascinating research projects that Ohio State students have completed outside Forum website, denman.osu.edu. You also can find undergraduate research theses at Ohio State's Knowledge activities across the university. We are grateful to Ohio State alumna Lindsey Perry, who created the image

  14. MATHEMATICAL SCIENCES UNDERGRADUATE

    E-print Network

    Wright, Francis

    ;#12;Mathematical Sciences Undergraduate Handbook 2009­10 Part 7: Module Details Module Details Modules are listed values; paid up policies. Books Reading List · McCutcheon & Scott, An Introduction to the Mathematics in the CMBR; galaxy formation: the growth of fluctuations; effect of hot and cold dark matter; viable galaxy

  15. UNDERGRADUATE DEGREES 2015 ENVIRONMENT

    E-print Network

    COME AND YOUR F I N D PLACE UNDERGRADUATE DEGREES 2015 EARTH and ENVIRONMENT #12;| CONTENTS | www OF EARTH AND ENVIRONMENT Why study earth and environment at Leeds? 2 Why study an earth science course? 4 Why study an environment course? 8 Choosing the right degree 12 Four-year industrial degrees (BA

  16. Undergraduate Faculty of Arts

    E-print Network

    Bristol, University of

    , logic and philosophical logic, philosophy of mathematics and philosophy of science (especially biology philosophy, and a competence in logic. You can also choose from a range of optional units introducing youUndergraduate Philosophy Faculty of Arts #12;bristol.ac.uk/study Philosophy is not a subject

  17. UNDERGRADUATE Materials Science & Engineering

    E-print Network

    Tipple, Brett

    UNDERGRADUATE HANDBOOK Materials Science & Engineering 2013 2014 #12;STUDYING FOR A MATERIALS SCIENCE AND ENGINEERING DEGREE Materials Science and Engineering inter-twines numerous disciplines that still gives the students the opportunity to study science while earning an engineering degree. Materials

  18. Undergraduate Faculty of Arts

    E-print Network

    Bristol, University of

    Undergraduate Italian Faculty of Arts #12;bristol.ac.uk/study Italian language and culture have had of experienced and qualified language-teaching experts, all Italian native speakers. The department offers students to extend their knowledge of Italian language and culture, network with Italian Erasmus students

  19. Undergraduate Faculty of Science

    E-print Network

    Bristol, University of

    . Uniquely, the MSci Human Geography course is recognised by the Economic and Social Research Council is foundational. All students receive an advanced overview of both human and physical geography, and developUndergraduate Geography Faculty of Science #12;bristol.ac.uk/study Geography is a wide

  20. Undergraduate Faculty of Science

    E-print Network

    Bristol, University of

    ), electroencephalography (EEG) recording, eye-tracking, sleep labs and a dedicated virtual reality environment. #12;bristol.ac.uk/studyUndergraduate Psychology Faculty of Science #12;bristol.ac.uk/study The basic curriculum of our BSc 2013) Studying psychology at Bristol was the first time I'd been encouraged to question the science

  1. Undergraduate Faculty of Medicine

    E-print Network

    Bristol, University of

    Undergraduate Dentistry Faculty of Medicine and Dentistry #12;bristol.ac.uk/study Dental surgeons as one of the leading dental schools in the UK. The school is part of the Faculty of Medicine in departments under the theme of Advanced Care Dentistry. These include Oral Medicine, where you will learn

  2. Undergraduate Faculty of Medicine

    E-print Network

    Bristol, University of

    Undergraduate Medicine Faculty of Medicine and Dentistry #12;bristol.ac.uk/study A medical degree direction in medicine. At Bristol your medical education will start with a thorough scientific understanding, multicultural and forward-thinking; a fantastic environment in which to learn and practise medicine. The Medical

  3. UNDERGRADUATE SPRING SYMPOSIUM

    E-print Network

    Gaucher, Eric

    of Architecture Building West Wing Atrium Sponsored by: Undergraduate Research Opportunities Program (UROP) #12. Lisa Yaszek, LCC 1:20pm Women's Empowerment After the Fall of the Taliban Summar Shoaib, INTA Mentor Plauche, Architecture Mentor: Dr. Sabir Khan, COA 3:40pm Random Projection and Learning David Mann

  4. Electrical Engineering UNDERGRADUATE

    E-print Network

    Suzuki, Masatsugu

    engineering is accredited by the Accreditation Board for Engineering and Technology (ABET). Students. Students also learn to design and conduct experiments, and to analyze and interpret data. To work for undergraduate participation in research. Graduates are prepared to undertake the self-motivated, lifelong

  5. Geography Undergraduate Program Management

    ERIC Educational Resources Information Center

    Estaville, Lawrence E.; Brown, Brock J.; Caldwell, Sally

    2006-01-01

    Vision and mission statements are the foundation for the types of undergraduate degrees departments confer as well as other types of academic programs such as pre-major, certificate, and distance education curricula. Critical to each department should be careful administration of course selections and offerings and management of academic majors,…

  6. Undergraduate Prospectus 2015

    E-print Network

    Levi, Ran

    more successful one. That makes Aberdeen an exciting and very special university to be part of. It 18 Learning Resources 20 An International University 22 Study Abroad 26 Careers 28 Student Life 30Undergraduate Prospectus 2015 #12;Estd. 1495 #12;#12;2 Welcome "Choosing a university is a very

  7. Working with Jewish Undergraduates

    ERIC Educational Resources Information Center

    Blumenfeld, Warren J.; Klein, Jacqueline R.

    2009-01-01

    The Jewish student population has received little attention on campuses and has indicated their disappointment with college administrators and faculty who do not understand their identity. Jewish undergraduates face many identity issues related to being Jewish, yet they have limited opportunities to learn about the impact of religion on their…

  8. Undergraduate Veterinary Nursing

    E-print Network

    Bristol, University of

    Undergraduate Veterinary Nursing and Bioveterinary Science Faculty of Medical and Veterinary. This exciting degree combines a high standard of education in both veterinary nursing and bioveterinary science and referral veterinary practice. This course enables you to develop your interest in science through studying

  9. HANDBOOK FOR UNDERGRADUATE STUDENTS

    E-print Network

    Kaji, Hajime

    #12;#12;HANDBOOK FOR UNDERGRADUATE STUDENTS OF THE FACULTY OF SCIENCE AND ENGINEERING 2011 Faculty of Science and Engineering Waseda University #12;This handbook contains information on academic policies of Science and Engineering. Be careful not to lose this handbook. Even though new handbooks are issued each

  10. engineering an undergraduate guide

    E-print Network

    Hart, Gus

    MECHANICAL engineering an undergraduate guide v #12;ENGINEER'S If it isn't broken, take it apart and fix it. motto: " " #12;TABLE OF CONTENTS 1. What is mechanical engineering? 1 2. What can a mechanical engineer do with their degree? 2 3. What companies have hired BYU mechanical engineering graduates? 3 4

  11. Upgrading Undergraduate Biology Education

    ERIC Educational Resources Information Center

    Musante, Susan

    2011-01-01

    On many campuses throughout the country, undergraduate biology education is in serious need of an upgrade. During the past few decades, the body of biological knowledge has grown exponentially, and as a research endeavor, the practice of biology has evolved. Education research has also made great strides, revealing many new insights into how…

  12. Computer Engineering Undergraduate Handbook

    E-print Network

    Acton, Scott

    Computer Engineering Undergraduate Handbook Bachelor of Science in Computer Engineering Presented by the Computer Science Department and the Charles L. Brown Department of Electrical & Computer Engineering Revised 2/10 Computer Engineering Program School of Engineering and Applied Science P.O. Box 400743

  13. Women's Studies (undergraduate)

    E-print Network

    Suzuki, Masatsugu

    348 Women's Studies (undergraduate) The Women's Studies Program offers an interdisciplinary course of study in the historical, economic, political, social and cultural experi- ence of women. The program courses in women's studies. Each semester the Women's Studies Department publishes a list of courses

  14. Economics Undergraduate BSc Economics

    E-print Network

    Burton, Geoffrey R.

    ;Undergraduate Economics Economics helps us answer questions, such as how should the banking system be regulated assessment period. Our programmes of study are modular, consisting of self- contained units, taught (measured through the number of credits awarded) is proportional to the number of learning hours, which

  15. Research Experience for Undergraduates

    E-print Network

    Tennessee, University of

    with Disabilities, and Underrepresented Students are encouraged to apply application deadline: March 15, 2015 applyResearch Experience for Undergraduates S t a r t D a te : J u n e 1 , 2 0 1 5 K n oxv i l l e , T N Networks (CURENT) is a National Science Foundation and Department of Energy Engineering Research Center

  16. IIT Architecture Undergraduate

    E-print Network

    Heller, Barbara

    IIT Architecture Chicago Undergraduate Programs #12;#12;NOWNESS is our approach. There are no more boundaries, no eternal forms. We should not attempt to define architecture in an all-encompassing way but instead make possible an architecture of freedom. Now is the time for opportunities of innovation. Now

  17. Undergraduate Student Research Travel Grant Purpose: To support undergraduate student research travel

    E-print Network

    Martin, Jeff

    Undergraduate Student Research Travel Grant Purpose: To support undergraduate student research of travel. · Students may only receive two Undergraduate Student Research Travel Grants throughout 15 General Information: · Applicants may only be awarded one Undergraduate Student Research Travel

  18. Research and Teaching: Undergraduate Science Learners Show Comparable Outcomes Whether Taught by Undergraduate or Graduate Teaching Assistants

    ERIC Educational Resources Information Center

    Chapin, Hannah C.; Wiggins, Benjamin L.; Martin-Morris, Linda E.

    2014-01-01

    Peer educators can be a powerful addition to classroom learning environments. Traditionally, the university science teaching model relies on graduate teaching assistants (GTAs) to provide instruction in laboratory class sessions, but there is increasing evidence that undergraduate TAs (UTAs) can fill an equivalent role. A comparison of student…

  19. 4/30/13 EBS AY13/14 Biochemistry and Molecular Biology

    E-print Network

    Chapman, Michael S.

    4/30/13 EBS AY13/14 Biochemistry and Molecular Biology Division of Environmental and Biomolecular and Molecular Biology ­ Master of Science ­ Nonthesis ............................2 Track: Biochemistry and Molecular Biology.................................................................................2

  20. 12/15/11 EBS AY11/12 Biochemistry and Molecular Biology

    E-print Network

    Chapman, Michael S.

    12/15/11 EBS AY11/12 Biochemistry and Molecular Biology Division of Environmental and Biomolecular and Molecular Biology ­ Master of Science ­ Nonthesis ............................2 Track: Biochemistry and Molecular Biology.................................................................................2

  1. 12/13/11 EBS AY10/11 Biochemistry and Molecular Biology

    E-print Network

    Chapman, Michael S.

    12/13/11 EBS AY10/11 Biochemistry and Molecular Biology Division of Environmental and Biomolecular and Molecular Biology ­ Master of Science ­ Nonthesis ............................2 Track: Biochemistry and Molecular Biology.................................................................................2

  2. 10/29/12 EBS AY12/13 Biochemistry and Molecular Biology

    E-print Network

    Chapman, Michael S.

    10/29/12 EBS AY12/13 Biochemistry and Molecular Biology Division of Environmental and Biomolecular and Molecular Biology ­ Master of Science ­ Nonthesis ............................2 Track: Biochemistry and Molecular Biology.................................................................................2

  3. 10/3/14 EBS AY14/15 Biochemistry and Molecular Biology

    E-print Network

    Chapman, Michael S.

    10/3/14 EBS AY14/15 Biochemistry and Molecular Biology Division of Environmental and Biomolecular and Molecular Biology ­ Master of Science ­ Nonthesis ...........................2 Track: Biochemistry and Molecular Biology.................................................................................2

  4. 12/21/09 DSE/BMB AY09/10 Biochemistry and Molecular Biology

    E-print Network

    Chapman, Michael S.

    12/21/09 DSE/BMB AY09/10 Biochemistry and Molecular Biology Division of Environmental and Molecular Biology ­ Master of Science ­ Nonthesis ............................2 Track: Biochemistry and Molecular Biology.................................................................................2 Degree

  5. A research associate level Developmental Biology/Cell Biology/Biochemistry Experimentalist to develop quantitative

    E-print Network

    Menczer, Filippo

    A research associate level Developmental Biology/Cell Biology/Biochemistry Experimentalist cell or developmental biology, pharmacology, toxicology, cell biology, or biochemistry and experience to cell regulation, cell signaling and cell behavior to extract the underlying biological models

  6. Paul Edward Smith Department of Biochemistry, 36 Willard Hall, Kansas State University

    E-print Network

    Smith, Paul E.

    Paul Edward Smith Department of Biochemistry, 36 Willard Hall, Kansas State University Manhattan, 1985 Research Experience Assistant Professor, 1996 to present, Department of Biochemistry, Kansas State University, Manhattan, Kansas. Research Assistant Professor, 1993 to 1996, Department of Chemistry

  7. Coproducts From Corn Processing 47 Applied Biochemistry and Biotechnology Vol. 128, 2006

    E-print Network

    Illinois at Urbana-Champaign, University of

    Coproducts From Corn Processing 47 Applied Biochemistry and Biotechnology Vol. 128, 2006 Copyright stability of dry-grind plants. #12;48 Rausch and Belyea Applied Biochemistry and Biotechnology Vol. 128

  8. Hemicellulose Depolymerization Model 53 Applied Biochemistry and Biotechnology Vol. 105108, 2003

    E-print Network

    California at Riverside, University of

    Hemicellulose Depolymerization Model 53 Applied Biochemistry and Biotechnology Vol. 105­108, 2003. Biologic process- #12;54 Lloyd and Wyman Applied Biochemistry and Biotechnology Vol. 105­108, 2003 ing

  9. Impact of Velocity on Corn Stover Pretreatment 977 Applied Biochemistry and Biotechnology Vol. 113116, 2004

    E-print Network

    California at Riverside, University of

    Impact of Velocity on Corn Stover Pretreatment 977 Applied Biochemistry and Biotechnology Vol. 113, and strategic benefits (1­5). #12;978 Liu and Wyman Applied Biochemistry and Biotechnology Vol. 113­116, 2004

  10. Mass Transfer Models for Hydrolysis 965 Applied Biochemistry and Biotechnology Vol. 113116, 2004

    E-print Network

    California at Riverside, University of

    Mass Transfer Models for Hydrolysis 965 Applied Biochemistry and Biotechnology Vol. 113­116, 2004 Biochemistry and Biotechnology Vol. 113­116, 2004 ity (2). For example, significant differences are observed

  11. Design of Batch Tube Reactor 377 Applied Biochemistry and Biotechnology Vol. 9193, 2001

    E-print Network

    California at Riverside, University of

    Design of Batch Tube Reactor 377 Applied Biochemistry and Biotechnology Vol. 91­93, 2001 Copyright Biochemistry and Biotechnology Vol. 91­93, 2001 pretreatment represents the most expensive single step

  12. Predicted Effect of Minerals on Pretreatment 1013 Applied Biochemistry and Biotechnology Vol. 113116, 2004

    E-print Network

    California at Riverside, University of

    Predicted Effect of Minerals on Pretreatment 1013 Applied Biochemistry and Biotechnology Vol. 113 of cellulose to cellulase enzymes has #12;1014 Lloyd and Wyman Applied Biochemistry and Biotechnology Vol. 113

  13. Sugar Monomer and Oligomer Solubility 179 Applied Biochemistry and Biotechnology Vol. 105108, 2003

    E-print Network

    California at Riverside, University of

    Sugar Monomer and Oligomer Solubility 179 Applied Biochemistry and Biotechnology Vol. 105­108, 2003 Biochemistry and Biotechnology Vol. 105­108, 2003 cellulose are essential to achieve this end. Elucidation

  14. BIOCHEMISTRY Britta Osborne | Academic Advisor/Recruiter

    E-print Network

    Logan, David

    . Elizabeth Regional Health Center · Histotech, Pathology Medical Services · Laboratory Technician, POET in medical technology and climate change (biofuels/plant biotechnology). Career opportunities Biologist, Midwest Research Inc · Research Technician II - Bio Process Development Facility, UNL Why

  15. A Sensitive and Robust Enzyme Kinetic Experiment Using Microplates and Fluorogenic Ester Substrates

    ERIC Educational Resources Information Center

    Johnson, R. Jeremy; Hoops, Geoffrey C.; Savas, Christopher J.; Kartje, Zachary; Lavis, Luke D.

    2015-01-01

    Enzyme kinetics measurements are a standard component of undergraduate biochemistry laboratories. The combination of serine hydrolases and fluorogenic enzyme substrates provides a rapid, sensitive, and general method for measuring enzyme kinetics in an undergraduate biochemistry laboratory. In this method, the kinetic activity of multiple protein…

  16. Blended learning in biochemistry education: analysis of medical students' perceptions.

    PubMed

    de Fátima Wardenski, Rosilaine; de Espíndola, Marina Bazzo; Struchiner, Miriam; Giannella, Taís Rabetti

    2012-07-01

    The objective of this study was to analyze first-year UFRJ medical students' perceptions about the implementation of a blended learning (BL) experience in their Biochemistry I course. During the first semester of 2009, three Biochemistry professors used the Constructore course management system to develop virtual learning environments (VLEs) for complementing course Modules I, II, and IV, using different resources and activities. Forty-nine students (46%) took part in the study. Results show that, in general, students gave positive evaluations to their experiences with BL, indicating that the VLEs have not only motivated but also facilitated learning. Most of the students reported that access to resources in the three modules provided a more in-depth approach to Biochemistry education and greater study autonomy. Students suggested that the VLEs could be better used for promoting greater communication among participants. PMID:22807424

  17. Argument-Driven Inquiry as a Way to Help Undergraduate Students Write to Learn by Learning to Write in Chemistry

    Microsoft Academic Search

    Victor Sampson; Joi Phelps Walker

    2012-01-01

    This exploratory study examined how undergraduate students’ ability to write in science changed over time as they completed a series of laboratory activities designed using a new instructional model called argument-driven inquiry. The study was conducted in a single section of an undergraduate general chemistry lab course offered at a large two-year community college located in the southeast USA. The

  18. Argument-Driven Inquiry as a Way to Help Undergraduate Students Write to Learn by Learning to Write in Chemistry

    ERIC Educational Resources Information Center

    Sampson, Victor; Walker, Joi Phelps

    2012-01-01

    This exploratory study examined how undergraduate students' ability to write in science changed over time as they completed a series of laboratory activities designed using a new instructional model called argument-driven inquiry. The study was conducted in a single section of an undergraduate general chemistry lab course offered at a large…

  19. Biochemistry Students' Ideas about Shape and Charge in Enzyme-Substrate Interactions

    ERIC Educational Resources Information Center

    Linenberger, Kimberly J.; Bretz, Stacey Lowery

    2014-01-01

    Biochemistry is a visual discipline that requires students to develop an understanding of numerous representations. However, there is very little known about what students actually understand about the representations that are used to communicate ideas in biochemistry. This study investigated biochemistry students' understanding of multiple…

  20. Inverting Organic and Biochemistry: A Curriculum Tweak That Benefits All

    NASA Astrophysics Data System (ADS)

    Reingold, I. David

    2004-04-01

    This article makes the case for re-ordering the material currently taught in sophomore organic chemistry and junior biochemistry courses, so that most of the biochemistry appears in the sophomore course and some of the more esoteric organic chemistry material is postponed until junior year. That way, nonmajors taking organic chemistry for career purposes (premedical students, biology majors, environmental scientists) will learn chemistry more relevant to them, and chemistry majors will not suffer by having anything left out. The article also proposes details of what topics should be moved from sophomore to junior year, and vice versa.