Science.gov

Sample records for union research database

  1. Database of small research watersheds for the territory of former Soviet Union as a source of data for improving hydrological models and their parameterizations in different geographical conditions

    NASA Astrophysics Data System (ADS)

    Lebedeva, Liudmila; Semenova, Olga

    2013-04-01

    One of widely claimed problems in modern modelling hydrology is lack of available information to investigate hydrological processes and improve their representation in the models. In spite of this, one hardly might confidently say that existing "traditional" data sources have been already fully analyzed and made use of. There existed the network of research watersheds in USSR called water-balance stations where comprehensive and extensive hydrometeorological measurements were conducted according to more or less single program during the last 40-60 years. The program (where not ceased) includes observations of discharges in several, often nested and homogeneous, small watersheds, meteorological elements, evaporation, soil temperature and moisture, snow depths, etc. The network covered different climatic and landscape zones and was established in the middle of the last century with the aim of investigation of the runoff formation in different conditions. Until recently the long-term observational data accompanied by descriptions and maps had existed only in hard copies. It partly explains why these datasets are not enough exploited yet and very rarely or even never were used for the purposes of hydrological modelling although they seem to be much more promising than implementation of the completely new measuring techniques not detracting from its importance. The goal of the presented work is development of a database of observational data and supportive materials from small research watersheds across the territory of the former Soviet Union. The first version of the database will include the following information for 12 water-balance stations across Russia, Ukraine, Kazahstan and Turkmenistan: daily values of discharges (one or several watersheds), air temperature, humidity, precipitation (one or several gauges), soil and snow state variables, soil and snow evaporation. The stations will cover desert and semi desert, steppe and forest steppe, forest, permafrost and mountainous zones. Supportive material will include maps of watershed boundaries and location of observational sites. Text descriptions of the data, measuring techniques and hydrometeorological conditions related to each of the water-balance station will accompany the datasets. The database is supposed to be expanded with time in number of the stations (by 20) and available data series for each of them. It will be uploaded to the internet with open access to everyone interested in. Such a database allows one to test hydrological models and separate modules for their adequacy and workability in different conditions and can serve as a base for models comparison and evaluation. Special profit of the database will gain models that don't rely on calibration but on the adequate process representation and use of the observable parameters. One of such models, process-based Hydrograph model, will be tested against the data from every watershed from the developed database. The aim of the Hydrograph model application to the as many as possible number of research data-rich watersheds in different climatic zones is both amending the algorithms and creation and adjustment of the model parameters that allow using the model across the geographic spectrum.

  2. Databases for Communications Research.

    ERIC Educational Resources Information Center

    Alberico, Ralph; Snow, Maxine

    Electronic databases have become important resources for researchers in many disciplines. While there is no single database designed to cover the field of communications, there are several databases which include material that is of interest to investigators in the field. An experiment was performed to determine which databases would be most…

  3. WHITHER BIOLOGICAL DATABASE RESEARCH?

    Technology Transfer Automated Retrieval System (TEKTRAN)

    We consider how the landscape of biological databases may evolve in the future, and what research is needed to realize this evolution. We suggest today's dispersal of diverse resources will only increase as the number and size of those resources, driving the need for semantic interoperability even ...

  4. International Scientific Unions and Global Research

    NASA Astrophysics Data System (ADS)

    Beer, T.

    2013-05-01

    This presentation will deal with the role that international scientific unions play in coordinating international research efforts. Rather than give a general, theoretical, talk on the role that ICSU - the International Council of Science - plays in International Science, I will briefly outline their role and then focus on a case study relevant to the International Union of Geodesy and Geophysics (IUGG). I will compare the scientific activities, and the outreach and education activities, of two major international research programs - the International Year of Planet Earth and the International Polar Year. These were two of the IGY+50 activities. Past informal polls of conference attendees to determine how many had heard of each IGY+50 event result in. eGY (electronic Geophysical Year) 1% IHY (International Heliophysical Year) 4% IYPE (International Year of Planet Earth) 31% IPY (International Polar Year) 64% Why is IPY the one of which most scientists are aware?

  5. Scientific research in the Soviet Union

    SciTech Connect

    Mtingwa, S.K.

    1990-03-19

    I report on the scientific aspects of my US/USSR Interacademy Exchange Visit to the Soviet Union. My research was conducted at three different institutes: the Lebedev Physical Institute in Moscow, the Leningrad Nuclear Physics Institute in Gatchina, and the Yerevan Physics Institute in Soviet Armenia. I included relevant information about the Soviet educational system, salaries of Soviet physicists, work habits and research activities at the three institutes, and the relevance of that research to work going on in the United States. 18 refs.

  6. Public database aids drug researchers

    Cancer.gov

    Researchers at the Broad Institute of Harvard and MIT have released ChemBank 2.0, a major upgrade to ChemBank, a publicly available database poised to enhance scientists' capabilities in drug discovery.

  7. Biological Databases for Human Research

    PubMed Central

    Zou, Dong; Ma, Lina; Yu, Jun; Zhang, Zhang

    2015-01-01

    The completion of the Human Genome Project lays a foundation for systematically studying the human genome from evolutionary history to precision medicine against diseases. With the explosive growth of biological data, there is an increasing number of biological databases that have been developed in aid of human-related research. Here we present a collection of human-related biological databases and provide a mini-review by classifying them into different categories according to their data types. As human-related databases continue to grow not only in count but also in volume, challenges are ahead in big data storage, processing, exchange and curation. PMID:25712261

  8. European Union vaccine research--an overview.

    PubMed

    Sautter, Jürgen; Olesen, Ole F; Bray, Jeremy; Draghia-Akli, Ruxandra

    2011-09-01

    Recent developments in vaccine research provide new momentum for an important area in health innovation. Particularly interesting are novel DNA vaccine approaches, many of which are already under clinical investigation. The Framework Programmes of the European Union play an important role in supporting collaborative efforts in vaccine research to develop new and better vaccines and bring them to the market. With a timely strategic reorientation towards a sustainable investment in innovation, the current seventh Framework Programme will help to bring large industry and small and medium-sized enterprises (SME) on board and foster partnership between stakeholders. As the first human DNA vaccines progresses through the development pipeline, more and more questions revolve around licensing and regulation and appropriate guidelines are being developed. PMID:21195799

  9. GMOMETHODS: the European Union database of reference methods for GMO analysis.

    PubMed

    Bonfini, Laura; Van den Bulcke, Marc H; Mazzara, Marco; Ben, Enrico; Patak, Alexandre

    2012-01-01

    In order to provide reliable and harmonized information on methods for GMO (genetically modified organism) analysis we have published a database called "GMOMETHODS" that supplies information on PCR assays validated according to the principles and requirements of ISO 5725 and/or the International Union of Pure and Applied Chemistry protocol. In addition, the database contains methods that have been verified by the European Union Reference Laboratory for Genetically Modified Food and Feed in the context of compliance with an European Union legislative act. The web application provides search capabilities to retrieve primers and probes sequence information on the available methods. It further supplies core data required by analytical labs to carry out GM tests and comprises information on the applied reference material and plasmid standards. The GMOMETHODS database currently contains 118 different PCR methods allowing identification of 51 single GM events and 18 taxon-specific genes in a sample. It also provides screening assays for detection of eight different genetic elements commonly used for the development of GMOs. The application is referred to by the Biosafety Clearing House, a global mechanism set up by the Cartagena Protocol on Biosafety to facilitate the exchange of information on Living Modified Organisms. The publication of the GMOMETHODS database can be considered an important step toward worldwide standardization and harmonization in GMO analysis. PMID:23451388

  10. Database Support for Research in Public Administration

    ERIC Educational Resources Information Center

    Tucker, James Cory

    2005-01-01

    This study examines the extent to which databases support student and faculty research in the area of public administration. A list of journals in public administration, public policy, political science, public budgeting and finance, and other related areas was compared to the journal content list of six business databases. These databases…

  11. Correlates of Access to Business Research Databases

    ERIC Educational Resources Information Center

    Gottfried, John C.

    2010-01-01

    This study examines potential correlates of business research database access through academic libraries serving top business programs in the United States. Results indicate that greater access to research databases is related to enrollment in graduate business programs, but not to overall enrollment or status as a public or private institution.…

  12. Correlates of Access to Business Research Databases

    ERIC Educational Resources Information Center

    Gottfried, John C.

    2010-01-01

    This study examines potential correlates of business research database access through academic libraries serving top business programs in the United States. Results indicate that greater access to research databases is related to enrollment in graduate business programs, but not to overall enrollment or status as a public or private institution.…

  13. Linguistic Analysis of Grant Proposals: European Union Research Grants.

    ERIC Educational Resources Information Center

    Connor, Ulla; Mauranen, Anna

    1999-01-01

    Analysis of 34 European-Union research-grant proposals written mainly by Finnish-led teams used genre analysis and a social constructionist theory of genre to investigate characteristic features of grant proposals, especially those not covered in academic writing courses. Ten recurrent moves were identified, reflecting the generic affinity of…

  14. Reforming Educational Reform: Teachers' Union Leading Teacher Research in Chile

    ERIC Educational Resources Information Center

    Montecinos, Carmen

    2009-01-01

    The teacher research movement in Chile has, historically, been an expression of the profession's concerns with the ways in which schooling reproduces and produces the social order in the broader society. The work currently done by members of the union's Pedagogical Movement is described, showing the connections between the scope of problems…

  15. Unions.

    PubMed

    Drane, D

    1990-05-01

    Dealing with a union is not complicated. If you are a member of the union, take that membership seriously and exercise your rights and responsibilities. Know what your contract says and live by it. If you disagree with what you are told to do by your supervisor, do it and grieve later. If you are a manager, know your contract and always keep it handy for reference. When you are unsure of the answer, get help from your labour relations advisor. Treat discipline as a process for helping an employee to perform the way you want them to perform. If you were a good manager before you became unionized, you can probably just continue on as you were before and you won't have any serious problems. For both management and non-management employees, remember that both of you have a job to do. Those jobs should be compatible. When you get to know your union, you will learn that they really are. PMID:10105432

  16. Public health research systems in the European union

    PubMed Central

    2011-01-01

    Background Strengthening health research is an important objective for international health organisations, but there has been less attention to support for health research in Europe. We describe the public-health (population and organisational level) research systems in the 27 European Union countries. Methods We developed a typology for describing health research structures based on funding streams and strategies. We drew data from internet sources and asked country informants to review these for consistency and completeness. The structures were described as organograms and narratives in country profiles for each of the 27 EU member states. National public-health research structures included public and independent funding organisations, 'mixed' institutions (which receive funds, and both use and allocate them) and provider institutions. Results Most health research is funded through ministries of science or science councils (and sometimes foundations), while parliaments and regions may also contribute. National institutes of public health are usually funded by ministries of health. Many national research organisations both determine research programmes and undertake health research, but there is a move towards public-health sciences within the universities, and a transition from internal grants to competitive funding. Of 27 national research strategies, 17 referred to health and 11 to public health themes. Although all countries had strategies for public health itself, we found little coherence in public-health research programmes. The European Commission has country contact points for both EU research and health programmes, but they do not coordinate with national health-research programmes. Conclusions Public-health research is broadly distributed across programmes in EU countries. Better understanding of research structures, programmes and results would improve recognition for public health in Europe, and contribute to practice. EU ministries of health should give greater attention to national public-health research strategies and programmes, and the European Union and the World Health Organisation can provide coordination and support. PMID:21970897

  17. Research on computer virus database management system

    NASA Astrophysics Data System (ADS)

    Qi, Guoquan

    2011-12-01

    The growing proliferation of computer viruses becomes the lethal threat and research focus of the security of network information. While new virus is emerging, the number of viruses is growing, virus classification increasing complex. Virus naming because of agencies' capture time differences can not be unified. Although each agency has its own virus database, the communication between each other lacks, or virus information is incomplete, or a small number of sample information. This paper introduces the current construction status of the virus database at home and abroad, analyzes how to standardize and complete description of virus characteristics, and then gives the information integrity, storage security and manageable computer virus database design scheme.

  18. Databases and QSAR for Cancer Research

    PubMed Central

    Malik, Adeel; Singh, Hemajit; Andrabi, Munazah; Husain, Syed Akhtar; Ahmad, Shandar

    2006-01-01

    In this review, we take a survey of bioinformatics databases and quantitative structure-activity relationship studies reported in published literature. Databases from the most general to special cancer-related ones have been included. Most commonly used methods of structure-based analysis of molecules have been reviewed, along with some case studies where they have been used in cancer research. This article is expected to be of use for general bioinformatics researchers interested in cancer and will also provide an update to those who have been actively pursuing this field of research. PMID:19458762

  19. TREATABILITY DATABASE (NATIONAL RISK MANAGEMENT RESEARCH LABORATORY)

    EPA Science Inventory

    The National Risk Management Research Laboratory has developed and is continuing to expand a database on the effectiveness of proven treatment technologies in the removal/destruction of chemicals in various types of media, including water, wastewater, soil, debris, sludge, and se...

  20. NATIVE HEALTH DATABASES: NATIVE HEALTH RESEARCH DATABASE (NHRD)

    EPA Science Inventory

    The Native Health Databases contain bibliographic information and abstracts of health-related articles, reports, surveys, and other resource documents pertaining to the health and health care of American Indians, Alaska Natives, and Canadian First Nations. The databases provide i...

  1. Biomedical journals and databases in Russia and Russian language in the former Soviet Union and beyond.

    PubMed

    Vlassov, Vasiliy V; Danishevskiy, Kirill D

    2008-01-01

    In the 20th century, Russian biomedical science experienced a decline from the blossom of the early years to a drastic state. Through the first decades of the USSR, it was transformed to suit the ideological requirements of a totalitarian state and biased directives of communist leaders. Later, depressing economic conditions and isolation from the international research community further impeded its development. Contemporary Russia has inherited a system of medical education quite different from the west as well as counterproductive regulations for the allocation of research funding. The methodology of medical and epidemiological research in Russia is largely outdated. Epidemiology continues to focus on infectious disease and results of the best studies tend to be published in international periodicals. MEDLINE continues to be the best database to search for Russian biomedical publications, despite only a small proportion being indexed. The database of the Moscow Central Medical Library is the largest national database of medical periodicals, but does not provide abstracts and full subject heading codes, and it does not cover even the entire collection of the Library. New databases and catalogs (e.g. Panteleimon) that have appeared recently are incomplete and do not enable effective searching. PMID:18826569

  2. Biomedical journals and databases in Russia and Russian language in the former Soviet Union and beyond

    PubMed Central

    Vlassov, Vasiliy V; Danishevskiy, Kirill D

    2008-01-01

    In the 20th century, Russian biomedical science experienced a decline from the blossom of the early years to a drastic state. Through the first decades of the USSR, it was transformed to suit the ideological requirements of a totalitarian state and biased directives of communist leaders. Later, depressing economic conditions and isolation from the international research community further impeded its development. Contemporary Russia has inherited a system of medical education quite different from the west as well as counterproductive regulations for the allocation of research funding. The methodology of medical and epidemiological research in Russia is largely outdated. Epidemiology continues to focus on infectious disease and results of the best studies tend to be published in international periodicals. MEDLINE continues to be the best database to search for Russian biomedical publications, despite only a small proportion being indexed. The database of the Moscow Central Medical Library is the largest national database of medical periodicals, but does not provide abstracts and full subject heading codes, and it does not cover even the entire collection of the Library. New databases and catalogs (e.g. Panteleimon) that have appeared recently are incomplete and do not enable effective searching. PMID:18826569

  3. The Cardiac Safety Research Consortium ECG database.

    PubMed

    Kligfield, Paul; Green, Cynthia L

    2012-01-01

    The Cardiac Safety Research Consortium (CSRC) ECG database was initiated to foster research using anonymized, XML-formatted, digitized ECGs with corresponding descriptive variables from placebo- and positive-control arms of thorough QT studies submitted to the US Food and Drug Administration (FDA) by pharmaceutical sponsors. The database can be expanded to other data that are submitted directly to CSRC from other sources, and currently includes digitized ECGs from patients with genotyped varieties of congenital long-QT syndrome; this congenital long-QT database is also linked to ambulatory electrocardiograms stored in the Telemetric and Holter ECG Warehouse (THEW). Thorough QT data sets are available from CSRC for unblinded development of algorithms for analysis of repolarization and for blinded comparative testing of algorithms developed for the identification of moxifloxacin, as used as a positive control in thorough QT studies. Policies and procedures for access to these data sets are available from CSRC, which has developed tools for statistical analysis of blinded new algorithm performance. A recently approved CSRC project will create a data set for blinded analysis of automated ECG interval measurements, whose initial focus will include comparison of four of the major manufacturers of automated electrocardiographs in the United States. CSRC welcomes application for use of the ECG database for clinical investigation. PMID:22999491

  4. Compensation of research-related injuries in the European Union.

    PubMed

    Avilds, Miguelangel Ramiro

    2014-12-01

    The planned reform of the Clinical Trials Directive has re-opened the debate over how to implement and interpret research-related injuries regulation. In the European Union (EU), clinical trials are currently regulated by Directive 2001/20/EC, which establishes the provision of mandatory insurance before clinical trials commence but is silent on the system of liability. The proposed new Regulation will impact biomedical research assurance in all EU Member States because it points to insurance costs as being one of the causes of the fall in the number of clinical trials carried out in the EU. Despite the adoption of a risk-balance approach, the proposed new Regulation does not include a no-fault compensation system to protect subjects participating in clinical trials. An adequate protection of the rights and wellbeing of trial subjects would require not only mandatory insurance for clinical trials but also a no-fault compensation system. The new regulation should include a general clause requiring mandatory insurance and establishing liability insurance based on no-fault compensation; an exception clause, enabling the performance of clinical trials without insurance in the case of low-risk interventions or non-commercial clinical trials; and an exclusion clause, excluding compensation when there is no causal connection between injuries and clinical trial. PMID:25486709

  5. CRITTER: A database for managing research animals

    PubMed Central

    Lees, V. Wayne; Lukey, Claire; Orr, Richard

    1993-01-01

    We describe CRITTER, a computer database program for managing research animals. We designed it especially for institutions which operate health surveillance plans, such as specific pathogen-free schemes. Because CRITTER can be used to record any type of test result in any species of animal, it can be customized to suit each institution and its management protocol. In addition to maintaining a current inventory of each individual animal and its location, the program retains historical information on those that have been removed from the colony. Output summaries are generated by selecting from a menu of standard reports or by designing a custom query. Although CRITTER has been designed for individual research establishments, it could be modified for use in area health surveillance programs. CRITTER operates on IBM compatible computers using a menu-driven, runtime version of Paradox. PMID:17424142

  6. CRITTER: A database for managing research animals.

    PubMed

    Lees, V W; Lukey, C; Orr, R

    1993-01-01

    We describe CRITTER, a computer database program for managing research animals. We designed it especially for institutions which operate health surveillance plans, such as specific pathogen-free schemes. Because CRITTER can be used to record any type of test result in any species of animal, it can be customized to suit each institution and its management protocol. In addition to maintaining a current inventory of each individual animal and its location, the program retains historical information on those that have been removed from the colony. Output summaries are generated by selecting from a menu of standard reports or by designing a custom query. Although CRITTER has been designed for individual research establishments, it could be modified for use in area health surveillance programs. CRITTER operates on IBM compatible computers using a menu-driven, runtime version of Paradox. PMID:17424142

  7. Medical research in emergency research in the European Union member states: tensions between theory and practice.

    PubMed

    Kompanje, Erwin J O; Maas, Andrew I R; Menon, David K; Kesecioglu, Jozef

    2014-04-01

    In almost all of the European Union member states, prior consent by a legal representative is used as a substitute for informed patient consent for non-urgent medical research. Deferred (patient and/or proxy) consent is accepted as a substitute in acute emergency research in approximately half of the member states. In 12 European Union member states emergency research is not mentioned in national law. Medical research in the European Union is covered by the Clinical Trial Directive 2001/20/EC. A proposal for a regulation by the European Commission is currently being examined by the European Parliament and the Council and will replace Directive 2001/20/EC. Deferred patient and/or proxy consent is allowed in the proposed regulation, but does not fit completely in the practice of emergency research. For example, deferred consent is only possible when legal representatives are not available. This criterion will delay inclusion of patients in acute life-threatening conditions in short time frames. As the regulation shall be binding in its entirety in all member states, emergency research in acute situations is still not possible as it should be. PMID:24570266

  8. Emission Database for Global Atmospheric Research (EDGAR).

    ERIC Educational Resources Information Center

    Olivier, J. G. J.; And Others

    1994-01-01

    Presents the objective and methodology chosen for the construction of a global emissions source database called EDGAR and the structural design of the database system. The database estimates on a regional and grid basis, 1990 annual emissions of greenhouse gases, and of ozone depleting compounds from all known sources. (LZ)

  9. Aggregated Interdisciplinary Databases and the Needs of Undergraduate Researchers

    ERIC Educational Resources Information Center

    Fister, Barbara; Gilbert, Julie; Fry, Amy Ray

    2008-01-01

    After seeing growing frustration among inexperienced undergraduate researchers searching a popular aggregated interdisciplinary database, the authors questioned whether the leading interdisciplinary databases are serving undergraduates' needs. As a preliminary exploration of this question, the authors queried vendors, analyzed their marketing…

  10. Aggregated Interdisciplinary Databases and the Needs of Undergraduate Researchers

    ERIC Educational Resources Information Center

    Fister, Barbara; Gilbert, Julie; Fry, Amy Ray

    2008-01-01

    After seeing growing frustration among inexperienced undergraduate researchers searching a popular aggregated interdisciplinary database, the authors questioned whether the leading interdisciplinary databases are serving undergraduates' needs. As a preliminary exploration of this question, the authors queried vendors, analyzed their marketing…

  11. Using a centralised database system and server in the European Union Framework Programme 7 project SEPServer

    NASA Astrophysics Data System (ADS)

    Heynderickx, Daniel

    2012-07-01

    The main objective of the SEPServer project (EU FP7 project 262773) is to produce a new tool, which greatly facilitates the investigation of solar energetic particles (SEPs) and their origin: a server providing SEP data, related electromagnetic (EM) observations and analysis methods, a comprehensive catalogue of the observed SEP events, and educational/outreach material on solar eruptions. The project is coordinated by the University of Helsinki. The project will combine data and knowledge from 11 European partners and several collaborating parties from Europe and US. The datasets provided by the consortium partners are collected in a MySQL database (using the ESA Open Data Interface under licence) on a server operated by DH Consultancy, which also hosts a web interface providing browsing, plotting and post-processing and analysis tools developed by the consortium, as well as a Solar Energetic Particle event catalogue. At this stage of the project, a prototype server has been established, which is presently undergoing testing by users inside the consortium. Using a centralized database has numerous advantages, including: homogeneous storage of the data, which eliminates the need for dataset specific file access routines once the data are ingested in the database; a homogeneous set of metadata describing the datasets on both a global and detailed level, allowing for automated access to and presentation of the various data products; standardised access to the data in different programming environments (e.g. php, IDL); elimination of the need to download data for individual data requests. SEPServer will, thus, add value to several space missions and Earth-based observations by facilitating the coordinated exploitation of and open access to SEP data and related EM observations, and promoting correct use of these data for the entire space research community. This will lead to new knowledge on the production and transport of SEPs during solar eruptions and facilitate the development of models for predicting solar radiation storms and calculation of expected fluxes/fluences of SEPs encountered by spacecraft in the interplanetary medium.

  12. Research Reveals Scale of College Union E-Commerce.

    ERIC Educational Resources Information Center

    Conway, Guy Patrick; Henry, Wilma J.

    2000-01-01

    Reports results of a survey of member schools of the Association of College Unions International concerning extent of e-commerce being conducted on the Web. College Web sites were also evaluated for information on e-commerce activities. A list of institutions currently conducting interactive business and the type of business being conducted is…

  13. Research Reveals Scale of College Union E-Commerce.

    ERIC Educational Resources Information Center

    Conway, Guy Patrick; Henry, Wilma J.

    2000-01-01

    Reports results of a survey of member schools of the Association of College Unions International concerning extent of e-commerce being conducted on the Web. College Web sites were also evaluated for information on e-commerce activities. A list of institutions currently conducting interactive business and the type of business being conducted is…

  14. The 2011 Nucleic Acids Research Database Issue and the online Molecular Biology Database Collection

    PubMed Central

    Galperin, Michael Y.; Cochrane, Guy R.

    2011-01-01

    The current 18th Database Issue of Nucleic Acids Research features descriptions of 96 new and 83 updated online databases covering various areas of molecular biology. It includes two editorials, one that discusses COMBREX, a new exciting project aimed at figuring out the functions of the ‘conserved hypothetical’ proteins, and one concerning BioDBcore, a proposed description of the ‘minimal information about a biological database’. Papers from the members of the International Nucleotide Sequence Database collaboration (INSDC) describe each of the participating databases, DDBJ, ENA and GenBank, principles of data exchange within the collaboration, and the recently established Sequence Read Archive. A testament to the longevity of databases, this issue includes updates on the RNA modification database, Definition of Secondary Structure of Proteins (DSSP) and Homology-derived Secondary Structure of Proteins (HSSP) databases, which have not been featured here in >12 years. There is also a block of papers describing recent progress in protein structure databases, such as Protein DataBank (PDB), PDB in Europe (PDBe), CATH, SUPERFAMILY and others, as well as databases on protein structure modeling, protein–protein interactions and the organization of inter-protein contact sites. Other highlights include updates of the popular gene expression databases, GEO and ArrayExpress, several cancer gene databases and a detailed description of the UK PubMed Central project. The Nucleic Acids Research online Database Collection, available at: http://www.oxfordjournals.org/nar/database/a/, now lists 1330 carefully selected molecular biology databases. The full content of the Database Issue is freely available online at the Nucleic Acids Research web site (http://nar.oxfordjournals.org/). PMID:21177655

  15. Research resource: the Endometrium Database Resource (EDR).

    PubMed

    Darlington, Yolanda; Jeong, Jae-Wook; Lee, Kevin Y; Franco, Heather L; Chen, Edward S; McOwiti, Apollo; Mistretta, Toni-Ann; Steffen, David; Becnel, Lauren; DeMayo, Francesco J

    2013-03-01

    In order to understand the biology of the endometrium and potentially develop new diagnostic tools and treatments for endometrial diseases, the highly orchestrated gene expression/regulation that occurs within the uterus must first be understood. Even though a wealth of information on endometrial gene expression/regulation is available, this information is scattered across several different resources in formats that can be difficult for the average bench scientist to query, integrate, and utilize. The Endometrium Database Resource (EDR) was created as a single evolving resource for protein- and micro-RNA-encoding genes that have been shown by gene expression microarray, Northern blot, or other experiments in the literature to have their expression regulated in the uterus of humans, mice, rats, cows, domestic pigs, guinea pigs, and sheep. Genes are annotated in EDR with basic gene information (eg, gene symbol and chromosome), gene orthologs, and gene ontologies. Links are also provided to external resources for publication/s, nucleic and amino acid sequence, gene product function, and Gene Expression Omnibus (GEO) phase expression graph information. The resource also allows for direct comparison of relative gene expression in different microarray experiments for genes shown in the literature to be differentially expressed in the uterus. It is available via a user-friendly, web-based interface and is available without charge or restriction to the entire scientific community. The EDR can be accessed at http://edr.research.bcm.edu. PMID:23340253

  16. The Cystic Fibrosis Database: Content and Research Opportunities.

    ERIC Educational Resources Information Center

    Shaw, William M., Jr.; And Others

    1991-01-01

    Describes the files contained in the Cystic Fibrosis (CF) database and discusses educational and research opportunities using this database. Topics discussed include queries, evaluating the relevance of items retrieved, and use of the database in an online searching course in the School of Information and Library Science at the University of North…

  17. The Cystic Fibrosis Database: Content and Research Opportunities.

    ERIC Educational Resources Information Center

    Shaw, William M., Jr.; And Others

    1991-01-01

    Describes the files contained in the Cystic Fibrosis (CF) database and discusses educational and research opportunities using this database. Topics discussed include queries, evaluating the relevance of items retrieved, and use of the database in an online searching course in the School of Information and Library Science at the University of North…

  18. The 2015 Nucleic Acids Research Database Issue and Molecular Biology Database Collection

    PubMed Central

    Galperin, Michael Y.; Rigden, Daniel J.; Fernández-Suárez, Xosé M.

    2015-01-01

    The 2015 Nucleic Acids Research Database Issue contains 172 papers that include descriptions of 56 new molecular biology databases, and updates on 115 databases whose descriptions have been previously published in NAR or other journals. Following the classification that has been introduced last year in order to simplify navigation of the entire issue, these articles are divided into eight subject categories. This year's highlights include RNAcentral, an international community portal to various databases on noncoding RNA; ValidatorDB, a validation database for protein structures and their ligands; SASBDB, a primary repository for small-angle scattering data of various macromolecular complexes; MoonProt, a database of ‘moonlighting’ proteins, and two new databases of protein–protein and other macromolecular complexes, ComPPI and the Complex Portal. This issue also includes an unusually high number of cancer-related databases and other databases dedicated to genomic basics of disease and potential drugs and drug targets. The size of NAR online Molecular Biology Database Collection, http://www.oxfordjournals.org/nar/database/a/, remained approximately the same, following the addition of 74 new resources and removal of 77 obsolete web sites. The entire Database Issue is freely available online on the Nucleic Acids Research web site (http://nar.oxfordjournals.org/). PMID:25593347

  19. The 2014 Nucleic Acids Research Database Issue and an updated NAR online Molecular Biology Database Collection.

    PubMed

    Fernández-Suárez, Xosé M; Rigden, Daniel J; Galperin, Michael Y

    2014-01-01

    The 2014 Nucleic Acids Research Database Issue includes descriptions of 58 new molecular biology databases and recent updates to 123 databases previously featured in NAR or other journals. For convenience, the issue is now divided into eight sections that reflect major subject categories. Among the highlights of this issue are six databases of the transcription factor binding sites in various organisms and updates on such popular databases as CAZy, Database of Genomic Variants (DGV), dbGaP, DrugBank, KEGG, miRBase, Pfam, Reactome, SEED, TCDB and UniProt. There is a strong block of structural databases, which includes, among others, the new RNA Bricks database, updates on PDBe, PDBsum, ArchDB, Gene3D, ModBase, Nucleic Acid Database and the recently revived iPfam database. An update on the NCBI's MMDB describes VAST+, an improved tool for protein structure comparison. Two articles highlight the development of the Structural Classification of Proteins (SCOP) database: one describes SCOPe, which automates assignment of new structures to the existing SCOP hierarchy; the other one describes the first version of SCOP2, with its more flexible approach to classifying protein structures. This issue also includes a collection of articles on bacterial taxonomy and metagenomics, which includes updates on the List of Prokaryotic Names with Standing in Nomenclature (LPSN), Ribosomal Database Project (RDP), the Silva/LTP project and several new metagenomics resources. The NAR online Molecular Biology Database Collection, http://www.oxfordjournals.org/nar/database/c/, has been expanded to 1552 databases. The entire Database Issue is freely available online on the Nucleic Acids Research website (http://nar.oxfordjournals.org/). PMID:24316579

  20. The 2014 Nucleic Acids Research Database Issue and an updated NAR online Molecular Biology Database Collection

    PubMed Central

    Fernández-Suárez, Xosé M.; Rigden, Daniel J.; Galperin, Michael Y.

    2014-01-01

    The 2014 Nucleic Acids Research Database Issue includes descriptions of 58 new molecular biology databases and recent updates to 123 databases previously featured in NAR or other journals. For convenience, the issue is now divided into eight sections that reflect major subject categories. Among the highlights of this issue are six databases of the transcription factor binding sites in various organisms and updates on such popular databases as CAZy, Database of Genomic Variants (DGV), dbGaP, DrugBank, KEGG, miRBase, Pfam, Reactome, SEED, TCDB and UniProt. There is a strong block of structural databases, which includes, among others, the new RNA Bricks database, updates on PDBe, PDBsum, ArchDB, Gene3D, ModBase, Nucleic Acid Database and the recently revived iPfam database. An update on the NCBI’s MMDB describes VAST+, an improved tool for protein structure comparison. Two articles highlight the development of the Structural Classification of Proteins (SCOP) database: one describes SCOPe, which automates assignment of new structures to the existing SCOP hierarchy; the other one describes the first version of SCOP2, with its more flexible approach to classifying protein structures. This issue also includes a collection of articles on bacterial taxonomy and metagenomics, which includes updates on the List of Prokaryotic Names with Standing in Nomenclature (LPSN), Ribosomal Database Project (RDP), the Silva/LTP project and several new metagenomics resources. The NAR online Molecular Biology Database Collection, http://www.oxfordjournals.org/nar/database/c/, has been expanded to 1552 databases. The entire Database Issue is freely available online on the Nucleic Acids Research website (http://nar.oxfordjournals.org/). PMID:24316579

  1. HIV research productivity and structural factors associated with HIV research output in European Union countries: a bibliometric analysis

    PubMed Central

    Uusküla, A; Toompere, K; Laisaar, K T; Rosenthal, M; Pürjer, M L; Knellwolf, A; Läärä, E; Des Jarlais, D C

    2015-01-01

    Objectives To assess HIV/AIDS research productivity in the 27 countries of the European Union (EU), and the structural level factors associated with levels of HIV/AIDS research productivity. Methods A bibliometric analysis was conducted with systematic search methods used to locate HIV/AIDS research publications (period of 1 January 2002 to 31 December 2011; search databases: MEDLINE (Ovid, PubMed), EMBASE, ISI-Thomson Web of Science; no language restrictions). The publication rate (number of HIV/AIDS research publications per million population in 10?years) and the rate of articles published in HIV/AIDS journals and selected journals with moderate to very high (IF ?3) 5-year impact factors were used as markers for HIV research productivity. A negative binomial regression model was fitted to assess the impact of structural level factors (sociodemographic, health, HIV prevalence and research/development indicators) associated with the variation in HIV research productivity. Results The total numbers of HIV/AIDS research publications in 2002–2011 by country ranged from 7 to 9128 (median 319). The median publication rate (per million population in 10?years) was 45 (range 5–150) for all publications. Across all countries, 16% of the HIV/AIDS research was published in HIV/AIDS journals and 7% in selected journals with IF ?3. Indicators describing economic (gross domestic product), demographic (size of the population) and epidemiological (HIV prevalence) conditions as well as overall scientific activity (total research output) in a country were positively associated with HIV research productivity. Conclusions HIV research productivity varies noticeably across EU countries, and this variation is associated with recognisable structural factors. PMID:25649212

  2. Clinical Research Databases, getting from Current State to Best Practice

    PubMed Central

    Waldren, Steven E.; Quetsch, Joseph

    2003-01-01

    Clinical research databases reside at the foundation of health sciences, yet experts outside of information science often manage research data. Improper data management presents risks to the researcher, research community, research subjects, and other patients. Data management must aim to preserve or maximize the value of data. We created a checklist tool for researchers and/or data administrators to use when evaluating their database operations. The tool addresses both liabilities and the value of the data. PMID:14728546

  3. The Human Communication Research Centre dialogue database.

    PubMed

    Anderson, A H; Garrod, S C; Clark, A; Boyle, E; Mullin, J

    1992-10-01

    The HCRC dialogue database consists of over 700 transcribed and coded dialogues from pairs of speakers aged from seven to fourteen. The speakers are recorded while tackling co-operative problem-solving tasks and the same pairs of speakers are recorded over two years tackling 10 different versions of our two tasks. In addition there are over 200 dialogues recorded between pairs of undergraduate speakers engaged on versions of the same tasks. Access to the database, and to its accompanying custom-built search software, is available electronically over the JANET system by contacting liz@psy.glasgow.ac.uk, from whom further information about the database and a user's guide to the database can be obtained. PMID:1429956

  4. The 2016 database issue of Nucleic Acids Research and an updated molecular biology database collection.

    PubMed

    Rigden, Daniel J; Fernández-Suárez, Xosé M; Galperin, Michael Y

    2016-01-01

    The 2016 Database Issue of Nucleic Acids Research starts with overviews of the resources provided by three major bioinformatics centers, the U.S. National Center for Biotechnology Information (NCBI), the European Bioinformatics Institute (EMBL-EBI) and Swiss Institute for Bioinformatics (SIB). Also included are descriptions of 62 new databases and updates on 95 databases that have been previously featured in NAR plus 17 previously described elsewhere. A number of papers in this issue deal with resources on nucleic acids, including various kinds of non-coding RNAs and their interactions, molecular dynamics simulations of nucleic acid structure, and two databases of super-enhancers. The protein database section features important updates on the EBI's Pfam, PDBe and PRIDE databases, as well as a variety of resources on pathways, metabolomics and metabolic modeling. This issue also includes updates on popular metagenomics resources, such as MG-RAST, EBI Metagenomics, and probeBASE, as well as a newly compiled Human Pan-Microbe Communities database. A significant fraction of the new and updated databases are dedicated to the genetic basis of disease, primarily cancer, and various aspects of drug research, including resources for patented drugs, their side effects, withdrawn drugs, and potential drug targets. A further six papers present updated databases of various antimicrobial and anticancer peptides. The entire Database Issue is freely available online on the Nucleic Acids Research website (http://nar.oxfordjournals.org/). The NAR online Molecular Biology Database Collection, http://www.oxfordjournals.org/nar/database/c/, has been updated with the addition of 88 new resources and removal of 23 obsolete websites, which brought the current listing to 1685 databases. PMID:26740669

  5. The 2016 database issue of Nucleic Acids Research and an updated molecular biology database collection

    PubMed Central

    Rigden, Daniel J.; Fernández-Suárez, Xosé M.; Galperin, Michael Y.

    2016-01-01

    The 2016 Database Issue of Nucleic Acids Research starts with overviews of the resources provided by three major bioinformatics centers, the U.S. National Center for Biotechnology Information (NCBI), the European Bioinformatics Institute (EMBL-EBI) and Swiss Institute for Bioinformatics (SIB). Also included are descriptions of 62 new databases and updates on 95 databases that have been previously featured in NAR plus 17 previously described elsewhere. A number of papers in this issue deal with resources on nucleic acids, including various kinds of non-coding RNAs and their interactions, molecular dynamics simulations of nucleic acid structure, and two databases of super-enhancers. The protein database section features important updates on the EBI's Pfam, PDBe and PRIDE databases, as well as a variety of resources on pathways, metabolomics and metabolic modeling. This issue also includes updates on popular metagenomics resources, such as MG-RAST, EBI Metagenomics, and probeBASE, as well as a newly compiled Human Pan-Microbe Communities database. A significant fraction of the new and updated databases are dedicated to the genetic basis of disease, primarily cancer, and various aspects of drug research, including resources for patented drugs, their side effects, withdrawn drugs, and potential drug targets. A further six papers present updated databases of various antimicrobial and anticancer peptides. The entire Database Issue is freely available online on the Nucleic Acids Research website (http://nar.oxfordjournals.org/). The NAR online Molecular Biology Database Collection, http://www.oxfordjournals.org/nar/database/c/, has been updated with the addition of 88 new resources and removal of 23 obsolete websites, which brought the current listing to 1685 databases. PMID:26740669

  6. Comparison Shopping of Tax Research Databases.

    ERIC Educational Resources Information Center

    Scanlan, Jean M.

    1990-01-01

    Examines and compares online sources for primary and secondary federal and state tax information. The criteria used to evaluate the four systems (CCH ACCESS, LEXIS, PHINet, and WESTLAW) include the contents of each database, search features, hardware requirements, software, pricing, availability of CD-ROM, online billing, and network…

  7. Natural image database and illuminant classification research

    NASA Astrophysics Data System (ADS)

    Tominaga, Shoji

    2001-12-01

    We introduce an image database called Natural Image Database of collecting natural color images that can be used via the Internet, and then show how it is used for illuminant classification and evaluate our sensor correlation method. A significant feature of the present database is inclusion of both image and illuminant data. It is not only a collection of color images taken a CCD camera, but also includes the calibration data of the camera used for image acquisition and the illuminant spectral data measured by a spectro-radiometer for each scene. Therefore, illuminant estimation algorithms can be evaluated on various natural scenes and comparison with the direct measurements. The illuminant classification is based on correlation computation between the gamut of an observed image and each of the reference illuminant gamuts. The illuminant gamuts of blackbody radiators are created from 2500K to 8500K in the RB sensor plane. The image gamut is defined as the convex hull of pixel values of the observed image. Then, one illuminant gamut is selected as the estimated illuminant, which gives an overall maximum of the correlation function. An experiment using the image database is executed for demonstrating the feasibility.

  8. How Europe Shapes Academic Research: Insights from Participation in European Union Framework Programmes

    ERIC Educational Resources Information Center

    Primeri, Emilia; Reale, Emanuela

    2012-01-01

    This article describes the effects of participating in European Union Framework Programmes (EUFPs) at the level of research units and researchers. We consider EUFPs as policy instruments that contribute to the Europeanisation of academic research and study the changes they produce with respect to: 1) the organisation and activities of Departments,…

  9. Implementation of the FAA research and development electromagnetic database

    NASA Technical Reports Server (NTRS)

    Mcdowall, R. L.; Grush, D. J.; Cook, D. M.; Glynn, M. S.

    1991-01-01

    The Idaho National Engineering Laboratory (INEL) has been assisting the FAA in developing a database of information about lightning. The FAA Research and Development Electromagnetic Database (FRED) will ultimately contain data from a variety of airborne and ground-based lightning research projects. An outline of the data currently available in FRED is presented. The data sources which the FAA intends to incorporate into FRED are listed. In addition, it describes how the researchers may access and use the FRED menu system.

  10. Emission database for global atmospheric research (Edgar).

    PubMed

    Olivier, J G; Bouwman, A F; van der Maas, C W; Berdowski, J J

    1994-05-01

    Atmospheric chemistry and climate modellers require gridded global emissions data as input into their models. To meet this urgent need a global emissions source database called EDGAR is being developed by TNO and RIVM to estimate for 1990, on a regional and on a grid basis, annual emissions of greenhouse gases (CO2, CH4, N2O, CO, NOx, non-methane VOC, SOx), of NH3, and of ozone depleting compounds (halocarbons) from all known sources. The aim is to establish at due levels of spatial, temporal and source aggregation the emissions from both anthropogenic and biogenic sources: a complete set of data required to estimate the total source strength of the various gases with a 1×1 ° resolution (altitude resolution of 1 km) and a temporal resolution of a month, supplemented by diurnal variation, as agreed upon in the Global Emissions Inventory Activity (GEIA) of the International Atmospheric Chemistry Programme (IGAC). In this way EDGAR will meet the requirements of present and future developments in the field of atmospheric modelling. The data comprise demographic data, social and economic factors, land use distributions and emission factors (with due emphasis on the uncertainty). As understanding in this field is still changing, due attention is paid to flexibility regarding the disaggregation of sources, spatial and temporal resolution and species. The objective and methodology chosen for the construction of the database and the structural design of the database system are presented, as well as the type and sources of data and the approach used for data collection. As an example, the construction of the N2O inventory is discussed. PMID:24213893

  11. So You Have a Research Idea: A Survey of Databases Available for Plastic Surgery Research.

    PubMed

    Adkinson, Joshua M; Casale, Mia T; Kim, John Y S; Khavanin, Nima; Gutowski, Karol A; Gosain, Arun K

    2016-02-01

    Plastic surgery research using large databases has increased dramatically over the past 20 years. With the magnitude and breadth of information available in these databases, researchers are able to more easily answer a wide variety of research questions. This study sought to provide a comprehensive comparative analysis of the relevant databases for plastic surgery research. Database information, data collection methods, acquisition details, and variable availability were collected for 19 large databases. Examples of potential future research utility were ascribed to each database based on this comprehensive analysis. With a greater understanding of the content, strengths, and limitations of these databases, researchers will be better equipped to select the most appropriate database to answer a specific research question. PMID:26818307

  12. Business Faculty Research: Satisfaction with the Web versus Library Databases

    ERIC Educational Resources Information Center

    Dewald, Nancy H.; Silvius, Matthew A.

    2005-01-01

    Business faculty members teaching at undergraduate campuses of the Pennsylvania State University were surveyed in order to assess their satisfaction with free Web sources and with subscription databases for their professional research. Although satisfaction with the Web's ease of use was higher than that for databases, overall satisfaction for…

  13. The Vocational Guidance Research Database: A Scientometric Approach

    ERIC Educational Resources Information Center

    Flores-Buils, Raquel; Gil-Beltran, Jose Manuel; Caballer-Miedes, Antonio; Martinez-Martinez, Miguel Angel

    2012-01-01

    The scientometric study of scientific output through publications in specialized journals cannot be undertaken exclusively with the databases available today. For this reason, the objective of this article is to introduce the "Base de Datos de Investigacion en Orientacion Vocacional" [Vocational Guidance Research Database], based on the use of…

  14. The Vocational Guidance Research Database: A Scientometric Approach

    ERIC Educational Resources Information Center

    Flores-Buils, Raquel; Gil-Beltran, Jose Manuel; Caballer-Miedes, Antonio; Martinez-Martinez, Miguel Angel

    2012-01-01

    The scientometric study of scientific output through publications in specialized journals cannot be undertaken exclusively with the databases available today. For this reason, the objective of this article is to introduce the "Base de Datos de Investigacion en Orientacion Vocacional" [Vocational Guidance Research Database], based on the use of…

  15. CottonDB: A database for cotton research

    Technology Transfer Automated Retrieval System (TEKTRAN)

    CottonDB, established in 1995, was among the first plant genome databases established by the USDA-ARS. The goal of CottonDB is to serve both as an archival and a dynamic database that incorporates data from all major categories of genetic and genomic information created by the cotton research commu...

  16. Drug delivery research in the European Union's Seventh Framework Programme for Research.

    PubMed

    Frima, Heico J; Gabellieri, Cristina; Nilsson, Maj-Inger

    2012-07-20

    This paper presents an overview of drug delivery research activities funded by the European Union's Seventh Framework Programme for Research and Technological Development (FP7). It gives a brief introduction of the main policies, structure and budget of FP7 with the four Specific Programmes 'Cooperation', 'People', 'Ideas' and 'Capacities' including the ten priority themes of the Specific Programme Cooperation. The priority themes HEALTH, 'Information and Communication Technologies' (ICT) and 'Nanosciences and nanotechnologies, multifunctional Materials and Production technologies' (NMP) and the 'Innovative Medicines Initiative' (IMI) are discussed since they are the main sources of funding for medical and pharmaceutical research. Further details are provided on drug delivery research, notably the funding for development of drug delivery technologies by the NMP priority theme in the context of its funding of nanomedicine research projects. The link is made to the rapidly developing field of biomaterials research for implants and regenerative medicine. The paper highlights the strategic importance of the Key Emerging Technologies (KETs) including nanotechnology for the competitiveness of the medical and pharmaceutical sectors. Finally, there is an outlook to the future Framework Programme for Research 'Horizon 2020'. PMID:22333557

  17. Public database aids drug researchers | Office of Cancer Genomics

    Cancer.gov

    Researchers at the Broad Institute of Harvard and MIT have released ChemBank 2.0, a major upgrade to ChemBank, a publicly available database poised to enhance scientists' capabilities in drug discovery.

  18. Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research

    PubMed Central

    Surati, Mosmi; Robinson, Matthew; Nandi, Suvobroto; Faoro, Leonardo; Demchuk, Carley; Kanteti, Rajani; Ferguson, Benjamin; Gangadhar, Tara; Hensing, Thomas; Hasina, Rifat; Husain, Aliya; Ferguson, Mark; Karrison, Theodore; Salgia, Ravi

    2011-01-01

    The Thoracic Oncology Program Database Project was created to serve as a comprehensive, verified, and accessible repository for well-annotated cancer specimens and clinical data to be available to researchers within the Thoracic Oncology Research Program. This database also captures a large volume of genomic and proteomic data obtained from various tumor tissue studies. A team of clinical and basic science researchers, a biostatistician, and a bioinformatics expert was convened to design the database. Variables of interest were clearly defined and their descriptions were written within a standard operating manual to ensure consistency of data annotation. Using a protocol for prospective tissue banking and another protocol for retrospective banking, tumor and normal tissue samples from patients consented to these protocols were collected. Clinical information such as demographics, cancer characterization, and treatment plans for these patients were abstracted and entered into an Access database. Proteomic and genomic data have been included in the database and have been linked to clinical information for patients described within the database. The data from each table were linked using the relationships function in Microsoft Access to allow the database manager to connect clinical and laboratory information during a query. The queried data can then be exported for statistical analysis and hypothesis generation. PMID:21304468

  19. Databases for multilevel biophysiology research available at Physiome.jp

    PubMed Central

    Asai, Yoshiyuki; Abe, Takeshi; Li, Li; Oka, Hideki; Nomura, Taishin; Kitano, Hiroaki

    2015-01-01

    Physiome.jp (http://physiome.jp) is a portal site inaugurated in 2007 to support model-based research in physiome and systems biology. At Physiome.jp, several tools and databases are available to support construction of physiological, multi-hierarchical, large-scale models. There are three databases in Physiome.jp, housing mathematical models, morphological data, and time-series data. In late 2013, the site was fully renovated, and in May 2015, new functions were implemented to provide information infrastructure to support collaborative activities for developing models and performing simulations within the database framework. This article describes updates to the databases implemented since 2013, including cooperation among the three databases, interactive model browsing, user management, version management of models, management of parameter sets, and interoperability with applications. PMID:26441671

  20. Carnegie Comes to Union Springs. The Development of an Alabama Public Library. A Research Proposal.

    ERIC Educational Resources Information Center

    Wright, A. J.

    This proposal examines the formation of the Carnegie Library at Union Springs, Alabama, in the context of the rural society from which it grew. It is suggested that the availability of detailed research into the dynamics of this library's formation may help historians identify factors that support the advent of public libraries, regardless of…

  1. Climate research in the former Soviet Union. FASAC: Foreign Applied Sciences Assessment Center technical assessment report

    SciTech Connect

    Ellingson, R.G.; Baer, F.; Ellsaesser, H.W.; Harshvardhan; Hoffert, M.I.; Randall, D.A.

    1993-09-01

    This report assesses the state of the art in several areas of climate research in the former Soviet Union. This assessment was performed by a group of six internationally recognized US experts in related fields. The areas chosen for review are: large-scale circulation processes in the atmosphere and oceans; atmospheric radiative processes; cloud formation processes; climate effects of natural atmospheric disturbances; and the carbon cycle, paleoclimates, and general circulation model validation. The study found an active research community in each of the above areas. Overall, the quality of climate research in the former Soviet Union is mixed, although the best Soviet work is as good as the best corresponding work in the West. The best Soviet efforts have principally been in theoretical studies or data analysis. However, an apparent lack of access to modern computing facilities has severely hampered the Soviet research. Most of the issues considered in the Soviet literature are known, and have been discussed in the Western literature, although some extraordinary research in paleoclimatology was noted. Little unusual and exceptionally creative material was found in the other areas during the study period (1985 through 1992). Scientists in the former Soviet Union have closely followed the Western literature and technology. Given their strengths in theoretical and analytical methods, as well as their possession of simplified versions of detailed computer models being used in the West, researchers in the former Soviet Union have the potential to make significant contributions if supercomputers, workstations, and software become available. However, given the current state of the economy in the former Soviet Union, it is not clear that the computer gap will be bridged in the foreseeable future.

  2. Implementation of the FAA research and development electromagnetic database

    SciTech Connect

    McDowall, R.L. ); Grush, D.J.; Cook, D.M. ); Glynn, M.S. . Technical Center)

    1991-01-01

    The Idaho National Engineering Laboratory (INEL) has been assisting the Federal Aviation Administration (FAA) in developing a database of information about lightning. The FAA Research and Development Electromagnetic Database (FRED) will ultimately contain data from a variety of airborne and groundbased lightning research projects. This paper contains an outline of the data currently available in FRED. It also lists the data sources which the FAA intends to incorporate into FRED. In addition, it describes how the researcher may access and use the FRED menu system. 2 refs., 12 figs.

  3. Sharing Heterogeneous Data: The National Database for Autism Research

    PubMed Central

    Hall, Dan; Huerta, Michael F.; McAuliffe, Matthew J.; Farber, Gregory K.

    2014-01-01

    The National Database for Autism Research (NDAR) is a secure research data repository designed to promote scientific data sharing and collaboration among autism spectrum disorder investigators. The goal of the project is to accelerate scientific discovery through data sharing, data harmonization, and the reporting of research results. Data from over 25,000 research participants are available to qualified investigators through the NDAR portal. Summary information about the available data is available to everyone through that portal. PMID:22622767

  4. An image database management system for conducting CAD research

    NASA Astrophysics Data System (ADS)

    Gruszauskas, Nicholas; Drukker, Karen; Giger, Maryellen L.

    2007-03-01

    The development of image databases for CAD research is not a trivial task. The collection and management of images and their related metadata from multiple sources is a time-consuming but necessary process. By standardizing and centralizing the methods in which these data are maintained, one can generate subsets of a larger database that match the specific criteria needed for a particular research project in a quick and efficient manner. A research-oriented management system of this type is highly desirable in a multi-modality CAD research environment. An online, webbased database system for the storage and management of research-specific medical image metadata was designed for use with four modalities of breast imaging: screen-film mammography, full-field digital mammography, breast ultrasound and breast MRI. The system was designed to consolidate data from multiple clinical sources and provide the user with the ability to anonymize the data. Input concerning the type of data to be stored as well as desired searchable parameters was solicited from researchers in each modality. The backbone of the database was created using MySQL. A robust and easy-to-use interface for entering, removing, modifying and searching information in the database was created using HTML and PHP. This standardized system can be accessed using any modern web-browsing software and is fundamental for our various research projects on computer-aided detection, diagnosis, cancer risk assessment, multimodality lesion assessment, and prognosis. Our CAD database system stores large amounts of research-related metadata and successfully generates subsets of cases that match the user's desired search criteria.

  5. Regulatory administrative databases in FDA's Center for Biologics Evaluation and Research: convergence toward a unified database.

    PubMed

    Smith, Jeffrey K

    2013-04-01

    Regulatory administrative database systems within the Food and Drug Administration's (FDA) Center for Biologics Evaluation and Research (CBER) are essential to supporting its core mission, as a regulatory agency. Such systems are used within FDA to manage information and processes surrounding the processing, review, and tracking of investigational and marketed product submissions. This is an area of increasing interest in the pharmaceutical industry and has been a topic at trade association conferences (Buckley 2012). Such databases in CBER are complex, not for the type or relevance of the data to any particular scientific discipline but because of the variety of regulatory submission types and processes the systems support using the data. Commonalities among different data domains of CBER's regulatory administrative databases are discussed. These commonalities have evolved enough to constitute real database convergence and provide a valuable asset for business process intelligence. Balancing review workload across staff, exploring areas of risk in review capacity, process improvement, and presenting a clear and comprehensive landscape of review obligations are just some of the opportunities of such intelligence. This convergence has been occurring in the presence of usual forces that tend to drive information technology (IT) systems development toward separate stovepipes and data silos. CBER has achieved a significant level of convergence through a gradual process, using a clear goal, agreed upon development practices, and transparency of database objects, rather than through a single, discrete project or IT vendor solution. This approach offers a path forward for FDA systems toward a unified database. PMID:23269527

  6. Improving the U.S. EPA Toxic Release Inventory database for environmental health research.

    PubMed

    Neumann, C M

    1998-01-01

    In 1986, Congress passed the Emergency Planning and Community Right-to-Know Act (EPCRA) in response to the tragic death of thousands of people in Bhopal, India, following the accidental release of the toxic gas methyl isocyanate (MIC) from a Union Carbide facility. As a component of EPCRA, certain manufacturers are required to report annually the total mass (pounds per year, lb/yr) of toxic chemicals released into the environment (air, water, land, or underground injection), treated on-site, or shipped off-site for further waste treatment. This information is compiled by the U.S. Environmental Protection Agency (EPA) into a publicly accessible database known as the Toxic Release Inventory (TRI). The TRI database is designed to encourage pollution prevention and waste reduction by increasing public access to and knowledge of environmental chemical releases. EPCRA has been generally considered by industry, government, and community representatives as one of the most successful environmental laws in U.S. history. Over the past few years, EPA has initiated a three-phased expansion to EPCRA reporting requirements that will enhance the overall usefulness of the TRI database. The focus of this article is to discuss these changes and highlight several current uses of the TRI database in environmental health research. PMID:9644330

  7. Norwegian words: A lexical database for clinicians and researchers.

    PubMed

    Lind, Marianne; Simonsen, Hanne Gram; Hansen, Pernille; Holm, Elisabeth; Mevik, Bjørn-Helge

    2015-04-01

    All words have properties linked to form, meaning and usage patterns which influence how easily they are accessed from the mental lexicon in language production, perception and comprehension. Examples of such properties are imageability, phonological and morphological complexity, word class, argument structure, frequency of use and age of acquisition. Due to linguistic and cultural variation the properties and the values associated with them differ across languages. Hence, for research as well as clinical purposes, language specific information on lexical properties is needed. To meet this need, an electronically searchable lexical database with more than 1600 Norwegian words coded for more than 12 different properties has been established. This article presents the content and structure of the database as well as the search options available in the interface. Finally, it briefly describes some of the ways in which the database can be used in research, clinical practice and teaching. PMID:25588015

  8. Current research status, databases and application of single nucleotide polymorphism.

    PubMed

    Javed, R; Mukesh

    2010-07-01

    Single Nucleotide Polymorphisms (SNPs) are the most frequent form of DNA variation in the genome. SNPs are genetic markers which are bi-allelic in nature and grow at a very fast rate. Current genomic databases contain information on several million SNPs. More than 6 million SNPs have been identified and the information is publicly available through the efforts of the SNP Consortium and others data bases. The NCBI plays a major role in facillating the identification and cataloging of SNPs through creation and maintenance of the public SNP database (dbSNP) by the biomedical community worldwide and stimulate many areas of biological research including the identification of the genetic components of disease. In this review article, we are compiling the existing SNP databases, research status and their application. PMID:21717869

  9. [Benefits of large healthcare databases for drug risk research].

    PubMed

    Garbe, Edeltraut; Pigeot, Iris

    2015-08-01

    Large electronic healthcare databases have become an important worldwide data resource for drug safety research after approval. Signal generation methods and drug safety studies based on these data facilitate the prospective monitoring of drug safety after approval, as has been recently required by EU law and the German Medicines Act. Despite its large size, a single healthcare database may include insufficient patients for the study of a very small number of drug-exposed patients or the investigation of very rare drug risks. For that reason, in the United States, efforts have been made to work on models that provide the linkage of data from different electronic healthcare databases for monitoring the safety of medicines after authorization in (i) the Sentinel Initiative and (ii) the Observational Medical Outcomes Partnership (OMOP). In July 2014, the pilot project Mini-Sentinel included a total of 178 million people from 18 different US databases. The merging of the data is based on a distributed data network with a common data model. In the European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCEPP) there has been no comparable merging of data from different databases; however, first experiences have been gained in various EU drug safety projects. In Germany, the data of the statutory health insurance providers constitute the most important resource for establishing a large healthcare database. Their use for this purpose has so far been severely restricted by the Code of Social Law (Section 75, Book 10). Therefore, a reform of this section is absolutely necessary. PMID:26092163

  10. Gas Hydrate Research Database and Web Dissemination Channel

    SciTech Connect

    Micheal Frenkel; Kenneth Kroenlein; V Diky; R.D. Chirico; A. Kazakow; C.D. Muzny; M. Frenkel

    2009-09-30

    To facilitate advances in application of technologies pertaining to gas hydrates, a United States database containing experimentally-derived information about those materials was developed. The Clathrate Hydrate Physical Property Database (NIST Standard Reference Database {number_sign} 156) was developed by the TRC Group at NIST in Boulder, Colorado paralleling a highly-successful database of thermodynamic properties of molecular pure compounds and their mixtures and in association with an international effort on the part of CODATA to aid in international data sharing. Development and population of this database relied on the development of three components of information-processing infrastructure: (1) guided data capture (GDC) software designed to convert data and metadata into a well-organized, electronic format, (2) a relational data storage facility to accommodate all types of numerical and metadata within the scope of the project, and (3) a gas hydrate markup language (GHML) developed to standardize data communications between 'data producers' and 'data users'. Having developed the appropriate data storage and communication technologies, a web-based interface for both the new Clathrate Hydrate Physical Property Database, as well as Scientific Results from the Mallik 2002 Gas Hydrate Production Research Well Program was developed and deployed at http://gashydrates.nist.gov.

  11. Systematically Retrieving Research: A Case Study Evaluating Seven Databases

    ERIC Educational Resources Information Center

    Taylor, Brian; Wylie, Emma; Dempster, Martin; Donnelly, Michael

    2007-01-01

    Objective: Developing the scientific underpinnings of social welfare requires effective and efficient methods of retrieving relevant items from the increasing volume of research. Method: We compared seven databases by running the nearest equivalent search on each. The search topic was chosen for relevance to social work practice with older people.…

  12. THE NATIONAL EXPOSURE RESEARCH LABORATORY'S COMPREHENSIVE HUMAN ACTIVITY DATABASE

    EPA Science Inventory

    EPA's National Exposure Research Laboratory (NERL) has combined data from nine U.S. studies related to human activities into one comprehensive data system that can be accessed via the world-wide web. The data system is called CHAD-Consolidated Human Activity Database-and it is ...

  13. THE NATIONAL EXPOSURE RESEARCH LABORATORY'S CONSOLIDATED HUMAN ACTIVITY DATABASE

    EPA Science Inventory

    EPA's National Exposure Research Laboratory (NERL) has combined data from 12 U.S. studies related to human activities into one comprehensive data system that can be accessed via the Internet. The data system is called the Consolidated Human Activity Database (CHAD), and it is ...

  14. Systematically Retrieving Research: A Case Study Evaluating Seven Databases

    ERIC Educational Resources Information Center

    Taylor, Brian; Wylie, Emma; Dempster, Martin; Donnelly, Michael

    2007-01-01

    Objective: Developing the scientific underpinnings of social welfare requires effective and efficient methods of retrieving relevant items from the increasing volume of research. Method: We compared seven databases by running the nearest equivalent search on each. The search topic was chosen for relevance to social work practice with older people.…

  15. Geoscience research databases for coastal Alabama ecosystem management

    USGS Publications Warehouse

    Hummell, Richard L.

    1995-01-01

    Effective management of complex coastal ecosystems necessitates access to scientific knowledge that can be acquired through a multidisciplinary approach involving Federal and State scientists that take advantage of agency expertise and resources for the benefit of all participants working toward a set of common research and management goals. Cooperative geostatic investigations have led toward building databases of fundamental scientific knowledge that can be utilized to manage coastal Alabama's natural and future development. These databases have been used to assess the occurrence and economic potential of hard mineral resources in the Alabama EFZ, and to support oil spill contingency planning and environmental analysis for coastal Alabama.

  16. Promoting operational research through fellowships: a case study from the South-East Asia Union Office.

    PubMed

    Kumar, A M V; Satyanarayana, S; Berger, S Dar; Chadha, S S; Singh, R J; Lal, P; Tonsing, J; Harries, A D

    2015-03-21

    In 2009, the International Union Against Tuberculosis and Lung Disease (The Union) and Médecins Sans Frontières (MSF) jointly developed a new paradigm for operational research (OR) capacity building and started a new process of appointing and supporting OR fellows in the field. This case study describes 1) the appointment of two OR fellows in The Union South-East Asia Office (USEA), New Delhi, India; 2) how this led to the development of an OR unit in that organisation; 3) achievements over the 5-year period from June 2009 to June 2014; and 4) challenges and lessons learnt. In June 2009, the first OR fellow in India was appointed on a full-time basis and the second was appointed in February 2012-both had limited previous experience in OR. From 2009 to 2014, annual research output and capacity building initiatives rose exponentially, and included 1) facilitation at 61 OR training courses/modules; 2) publication of 96 papers, several of which had a lasting impact on national policy and practice; 3) providing technical assistance in promoting OR; 4) building the capacity of medical college professionals in data management; 5) support to programme staff for disseminating their research findings; 6) reviewing 28 scientific papers for national or international peer-reviewed journals; and 7) developing 45 scientific abstracts for presentation at national and international conferences. The reasons for this success are highlighted along with ongoing challenges. This experience from India provides good evidence for promoting similar models elsewhere. PMID:26400596

  17. Building an Ontology-driven Database for Clinical Immune Research

    PubMed Central

    Ma, Jingming

    2006-01-01

    The clinical researches of immune response usually generate a huge amount of biomedical testing data over a certain period of time. The user-friendly data management systems based on the relational database will help immunologists/clinicians to fully manage the data. On the other hand, the same biological assays such as ELISPOT and flow cytometric assays are involved in immunological experiments no matter of different study purposes. The reuse of biological knowledge is one of driving forces behind this ontology-driven data management. Therefore, an ontology-driven database will help to handle different clinical immune researches and help immunologists/clinicians easily understand the immunological data from each other. We will discuss some outlines for building an ontology-driven data management for clinical immune researches (ODMim). PMID:17238637

  18. The imperiled future of solar-terrestrial research in the former Soviet Union

    NASA Astrophysics Data System (ADS)

    Roederer, Juan G.; Teague, Michael

    From the beginning of solar-terrestrial research (STR) during the International Geophysical Year 1957/58, the Soviet Union made substantial contributions to this new discipline. In many areas, such as magnetic pulsations, cosmic ray modulation, plasmasphere structure and dynamics, ionospheric modification, theoretical space plasma physics, and planetary ionospheres, Soviet scientists have pioneered and excelled.Some unique facts call for vigorous participation by the former Soviet Union (FSU) in the Solar-Terrestrial Energy Program 1990-1997 (STEP) of the International Council of Scientific Unions (ICSU) Scientific Committee on Solar-Terrestrial Physics (SCOSTEP) (see, for instance, Rostoker [1990]). There are the existing brain power in many related disciplines, with particular strength in theoretical physics and analytical methods; the area's geographic importance, especially Russia's vast longitudinal extent at high northern latitudes; the existing magnetic, optical, and ionospheric observatory networks throughout the country, especially in the Arctic and important Antarctic bases; space mission capability with existing and planned satellite missions and a stock of available prototype spacecraft with their launch vehicles; an existing bank of STR data, some of it formerly classified, waiting to be analyzed; and ongoing research on “controversialrdquo topics such as the search for solar-terrestrial coupling effects on biological and human systems and the study of earthquake precursor effects in the ionosphere.

  19. Concierge: personal database software for managing digital research resources.

    PubMed

    Sakai, Hiroyuki; Aoyama, Toshihiro; Yamaji, Kazutsuna; Usui, Shiro

    2007-01-01

    This article introduces a desktop application, named Concierge, for managing personal digital research resources. Using simple operations, it enables storage of various types of files and indexes them based on content descriptions. A key feature of the software is a high level of extensibility. By installing optional plug-ins, users can customize and extend the usability of the software based on their needs. In this paper, we also introduce a few optional plug-ins: literature management, electronic laboratory notebook, and XooNlps client plug-ins. XooNIps is a content management system developed to share digital research resources among neuroscience communities. It has been adopted as the standard database system in Japanese neuroinformatics projects. Concierge, therefore, offers comprehensive support from management of personal digital research resources to their sharing in open-access neuroinformatics databases such as XooNIps. This interaction between personal and open-access neuroinformatics databases is expected to enhance the dissemination of digital research resources. Concierge is developed as an open source project; Mac OS X and Windows XP versions have been released at the official site (http://concierge.sourceforge.jp). PMID:18974800

  20. Emerging technologies and perspectives for nutrition research in European Union 7th Framework Programme.

    PubMed

    de Froidmont-Görtz, Isabelle B M

    2009-12-01

    Nutrition trends in Europe are driven by taste, health and convenience. The possibilities of research using new technologies and tools such as nutrigenomics, imaging techniques, nanotechnology, bioinformatics, cognitive sciences, innovative processes are very promising to support these nutrition trends and in particular their health aspects. This is supported by European Union research. The opportunities offered in the 7th Framework Programme (FP7), among other innovations, will contribute to the general aim of improving nutrition policy as well as improving products from the food industry in accordance with the Lisbon strategy to create employment and improve the quality of life of the European citizens. PMID:19937440

  1. Mapping Health Literacy Research in the European Union: A Bibliometric Analysis

    PubMed Central

    Kondilis, Barbara K.; Kiriaze, Ismene J.; Athanasoulia, Anastasia P.; Falagas, Matthew E.

    2008-01-01

    Background To examine and compare the research productivity on selected fields related to health literacy of the current members of the European Union, the four candidate countries waiting to join the EU, Norway, Switzerland, and the United States. Methodology/Principal findings A bibliometric analysis (1991–2005). Data sources included papers published by authors from each country separately. The 25 European countries produce less than 1/3 health literacy research when compared to the U.S. (13,710 and 49,523 articles were published by authors with main affiliation in the European Union and the four candidate countries, and the U.S., respectively). The Netherlands and Sweden (followed by Germany, Italy, and France) are the European countries with the highest number of research published in fields related to health literacy. After adjustment for population Sweden, Finland, and Norway, were on the top of the relevant list. In addition, Sweden, Finland, and Ireland, were on the top of the list of countries regarding research productivity on the selected fields after adjustment for gross domestic product (GDP). Conclusions/Significance Inequalities in research published on the topic of health literacy exist among Europe, Norway, Switzerland, and the U.S. More research may need to be done in all areas of health literacy in Europe and the potential detrimental effects of this gap should be further investigated. PMID:18575594

  2. Advanced Satellite Research Project: SCAR Research Database. Bibliographic analysis

    NASA Technical Reports Server (NTRS)

    Pelton, Joseph N.

    1991-01-01

    The literature search was provided to locate and analyze the most recent literature that was relevant to the research. This was done by cross-relating books, articles, monographs, and journals that relate to the following topics: (1) Experimental Systems - Advanced Communications Technology Satellite (ACTS), and (2) Integrated System Digital Network (ISDN) and Advance Communication Techniques (ISDN and satellites, ISDN standards, broadband ISDN, flame relay and switching, computer networks and satellites, satellite orbits and technology, satellite transmission quality, and network configuration). Bibliographic essay on literature citations and articles reviewed during the literature search task is provided.

  3. U.S. Army Research Laboratory (ARL) multimodal signatures database

    NASA Astrophysics Data System (ADS)

    Bennett, Kelly

    2008-04-01

    The U.S. Army Research Laboratory (ARL) Multimodal Signatures Database (MMSDB) is a centralized collection of sensor data of various modalities that are co-located and co-registered. The signatures include ground and air vehicles, personnel, mortar, artillery, small arms gunfire from potential sniper weapons, explosives, and many other high value targets. This data is made available to Department of Defense (DoD) and DoD contractors, Intel agencies, other government agencies (OGA), and academia for use in developing target detection, tracking, and classification algorithms and systems to protect our Soldiers. A platform independent Web interface disseminates the signatures to researchers and engineers within the scientific community. Hierarchical Data Format 5 (HDF5) signature models provide an excellent solution for the sharing of complex multimodal signature data for algorithmic development and database requirements. Many open source tools for viewing and plotting HDF5 signatures are available over the Web. Seamless integration of HDF5 signatures is possible in both proprietary computational environments, such as MATLAB, and Free and Open Source Software (FOSS) computational environments, such as Octave and Python, for performing signal processing, analysis, and algorithm development. Future developments include extending the Web interface into a portal system for accessing ARL algorithms and signatures, High Performance Computing (HPC) resources, and integrating existing database and signature architectures into sensor networking environments.

  4. Promoting operational research through fellowships: a case study from the South-East Asia Union Office

    PubMed Central

    Satyanarayana, S.; Berger, S. Dar; Chadha, S. S.; Singh, R. J.; Lal, P.; Tonsing, J.; Harries, A. D.

    2015-01-01

    In 2009, the International Union Against Tuberculosis and Lung Disease (The Union) and Médecins Sans Frontières (MSF) jointly developed a new paradigm for operational research (OR) capacity building and started a new process of appointing and supporting OR fellows in the field. This case study describes 1) the appointment of two OR fellows in The Union South-East Asia Office (USEA), New Delhi, India; 2) how this led to the development of an OR unit in that organisation; 3) achievements over the 5-year period from June 2009 to June 2014; and 4) challenges and lessons learnt. In June 2009, the first OR fellow in India was appointed on a full-time basis and the second was appointed in February 2012—both had limited previous experience in OR. From 2009 to 2014, annual research output and capacity building initiatives rose exponentially, and included 1) facilitation at 61 OR training courses/modules; 2) publication of 96 papers, several of which had a lasting impact on national policy and practice; 3) providing technical assistance in promoting OR; 4) building the capacity of medical college professionals in data management; 5) support to programme staff for disseminating their research findings; 6) reviewing 28 scientific papers for national or international peer-reviewed journals; and 7) developing 45 scientific abstracts for presentation at national and international conferences. The reasons for this success are highlighted along with ongoing challenges. This experience from India provides good evidence for promoting similar models elsewhere. PMID:26400596

  5. The Union RAP: Industry-Wide Research-Action Projects to Win Health and Safety Improvements

    PubMed Central

    McQuiston, Thomas H.; Lippin, Tobi Mae; Anderson, Leeann G.; Beach, M. Josie; Frederick, James; Seymour, Thomas A.

    2009-01-01

    Unions are ripe to engage in community-based participatory research (CBPR). We briefly profile 3 United Steelworker CBPR projects aimed at uncovering often-undocumented, industry-wide health and safety conditions in which US industrial workers toil. The results are to be used to advocate improvements at workplace, industry, and national policy levels. We offer details of our CBPR approach (Research-Action Project [RAP]) that engages workers and others in all research stages. Elements of RAPs include strategically constructed teams with knowledge of the industry and health and safety and with skills in research, participatory facilitation, and training; reciprocal training on these knowledge and skill areas; iterative processes of large and small group work; use of technology; and facilitator-developed tools and intermediate products. PMID:19890145

  6. What happens after participants complete a Union-MSF structured operational research training course?

    PubMed Central

    Guillerm, N.; Tayler-Smith, K.; Berger, S. D.; Bissell, K.; Kumar, A. M. V.; Ramsay, A.; Reid, A. J.; Zachariah, R.

    2014-01-01

    Setting: Eight operational research (OR) courses run by the International Union Against Tuberculosis and Lung Disease (The Union) and Médecins Sans Frontières (MSF) for participants from low- and middle-income countries. There is a knowledge gap about whether participants continue OR after course completion. Objectives: To determine 1) the research output of participants and their institutions after course completion; 2) the influence of OR fellowships on output; and 3) the output of non-OR fellows stratified by sex, region and staff position. Design: A self-administered e-mail questionnaire survey. Results: Of 83 participants who completed a course, 76 (92%) responded to the questionnaire. Following course completion, 47 (62%) participants completed new research projects, 38 (50%) published papers (vs. 25 [33%] who had published before the course), 42 (55%) presented posters or oral abstracts at conferences, 33 (43%) facilitated at further OR courses, 29 (38%) reviewed scientific papers, 25 (33%) secured further OR funding and 55 (72%) said their institutions were involved in OR implementation or capacity building. OR fellows performed better than non-OR fellows. Among the latter, males and participants from Asia had better output than females and participants from Africa (P < 0.05). Conclusion: The significant proportion of participants continuing to engage in OR after course completion provides encouraging evidence of the long-term value of this capacity building model. PMID:26399205

  7. French health insurance databases: What interest for medical research?

    PubMed

    Moulis, G; Lapeyre-Mestre, M; Palmaro, A; Pugnet, G; Montastruc, J-L; Sailler, L

    2015-06-01

    French health insurance databases are organized since 2003 into a huge digital data warehouse, the Système national d'information inter-régime de l'assurance maladie (SNIIR-AM). It covers the entire French population (65 million inhabitants). In order to facilitate studies on more frequent conditions, a random sample of 1/97th of national health system beneficiaries has been built since 2005, called the échantillon généraliste des bénéficiaires (EGB). The aim of this article is to describe the main characteristics of the SNIIR-AM and the EGB, to detail their accessibility according to French law, and to present their strengths and limits. It is illustrated with the most recent studies conducted in these databases. These databases include demographic, out-hospital reimbursement (including drug dispensing), medical (costly long-term diseases, occupational diseases, sick-leaves…), and in-hospital data. All these data are prospectively recorded, individualized, made anonymous and linkable. Consequently, the SNIIR-AM is a very useful data source for epidemiological, pharmacoepidemiological and health economics studies, particularly for rare diseases. The EGB is appropriate for long-term research on more frequent diseases. PMID:25547954

  8. Development of a database for translational spinal cord injury research.

    PubMed

    Nielson, Jessica L; Guandique, Cristian F; Liu, Aiwen W; Burke, Darlene A; Lash, A Todd; Moseanko, Rod; Hawbecker, Stephanie; Strand, Sarah C; Zdunowski, Sharon; Irvine, Karen-Amanda; Brock, John H; Nout-Lomas, Yvette S; Gensel, John C; Anderson, Kim D; Segal, Mark R; Rosenzweig, Ephron S; Magnuson, David S K; Whittemore, Scott R; McTigue, Dana M; Popovich, Phillip G; Rabchevsky, Alexander G; Scheff, Stephen W; Steward, Oswald; Courtine, Grégoire; Edgerton, V Reggie; Tuszynski, Mark H; Beattie, Michael S; Bresnahan, Jacqueline C; Ferguson, Adam R

    2014-11-01

    Efforts to understand spinal cord injury (SCI) and other complex neurotrauma disorders at the pre-clinical level have shown progress in recent years. However, successful translation of basic research into clinical practice has been slow, partly because of the large, heterogeneous data sets involved. In this sense, translational neurological research represents a "big data" problem. In an effort to expedite translation of pre-clinical knowledge into standards of patient care for SCI, we describe the development of a novel database for translational neurotrauma research known as Visualized Syndromic Information and Outcomes for Neurotrauma-SCI (VISION-SCI). We present demographics, descriptive statistics, and translational syndromic outcomes derived from our ongoing efforts to build a multi-center, multi-species pre-clinical database for SCI models. We leveraged archived surgical records, postoperative care logs, behavioral outcome measures, and histopathology from approximately 3000 mice, rats, and monkeys from pre-clinical SCI studies published between 1993 and 2013. The majority of animals in the database have measures collected for health monitoring, such as weight loss/gain, heart rate, blood pressure, postoperative monitoring of bladder function and drug/fluid administration, behavioral outcome measures of locomotion, and tissue sparing postmortem. Attempts to align these variables with currently accepted common data elements highlighted the need for more translational outcomes to be identified as clinical endpoints for therapeutic testing. Last, we use syndromic analysis to identify conserved biological mechanisms of recovery after cervical SCI between rats and monkeys that will allow for more-efficient testing of therapeutics that will need to be translated toward future clinical trials. PMID:25077610

  9. Development of a Database for Translational Spinal Cord Injury Research

    PubMed Central

    Nielson, Jessica L.; Guandique, Cristian F.; Liu, Aiwen W.; Burke, Darlene A.; Lash, A. Todd; Moseanko, Rod; Hawbecker, Stephanie; Strand, Sarah C.; Zdunowski, Sharon; Irvine, Karen-Amanda; Brock, John H.; Nout-Lomas, Yvette S.; Gensel, John C.; Anderson, Kim D.; Segal, Mark R.; Rosenzweig, Ephron S.; Magnuson, David S.K.; Whittemore, Scott R.; McTigue, Dana M.; Popovich, Phillip G.; Rabchevsky, Alexander G.; Scheff, Stephen W.; Steward, Oswald; Courtine, Grégoire; Edgerton, V. Reggie; Tuszynski, Mark H.; Beattie, Michael S.; Bresnahan, Jacqueline C.

    2014-01-01

    Abstract Efforts to understand spinal cord injury (SCI) and other complex neurotrauma disorders at the pre-clinical level have shown progress in recent years. However, successful translation of basic research into clinical practice has been slow, partly because of the large, heterogeneous data sets involved. In this sense, translational neurological research represents a “big data” problem. In an effort to expedite translation of pre-clinical knowledge into standards of patient care for SCI, we describe the development of a novel database for translational neurotrauma research known as Visualized Syndromic Information and Outcomes for Neurotrauma-SCI (VISION-SCI). We present demographics, descriptive statistics, and translational syndromic outcomes derived from our ongoing efforts to build a multi-center, multi-species pre-clinical database for SCI models. We leveraged archived surgical records, postoperative care logs, behavioral outcome measures, and histopathology from approximately 3000 mice, rats, and monkeys from pre-clinical SCI studies published between 1993 and 2013. The majority of animals in the database have measures collected for health monitoring, such as weight loss/gain, heart rate, blood pressure, postoperative monitoring of bladder function and drug/fluid administration, behavioral outcome measures of locomotion, and tissue sparing postmortem. Attempts to align these variables with currently accepted common data elements highlighted the need for more translational outcomes to be identified as clinical endpoints for therapeutic testing. Last, we use syndromic analysis to identify conserved biological mechanisms of recovery after cervical SCI between rats and monkeys that will allow for more-efficient testing of therapeutics that will need to be translated toward future clinical trials. PMID:25077610

  10. Databases and collaboration require standards for human stem cell research.

    PubMed

    Litterman, Nadia K; Ekins, Sean

    2015-02-01

    Stem cell research is at an important juncture: despite significant potential for human health and several countries with key initiatives to expedite commercialization, there are gaps in capturing and exploiting the results of past and current research. Here, we propose a concerted plan that could be taken to foster a more collaborative approach and ensure that all research efforts can be leveraged across the community. The creation of a definitive centralized database repository, or at least harmonized data repositories, for stem cell groups in academia and industry, enabling secure selective sharing of data when needed, could provide the core structure that is sought globally and protect intellectual property. The development of minimum information about stem cell experiments (MIASCE) could be key to this development. PMID:25449658

  11. STEMdex: A Searchable Database of Education Research for Our Community

    NASA Astrophysics Data System (ADS)

    Brinkworth, Carolyn; Nichols-Yehling, M.; Bartolone, L.; Llamas, J.; Crane, M.; Martin, A.; Wenger, M.; Squires, G. K.; Hurt, R. L.

    2014-01-01

    STEMdex is a new resource for the astronomy Education and Outreach community, designed to improve our community’s knowledge of the published literature pertinent to our work. While we all understand that it is important to base our practice on sound research, there are currently 801 peer-reviewed education journals in existence, and members of our community are hard pressed to cover all the published literature. STEMdex consolidates the research relevant to EPO work into a single searchable database, with summaries written by astronomy educators and posted for the entire community to use. The database will ultimately include research across the spectrum of astronomy education, including formal and informal education, outreach, grades K-16, pedagogy, evaluation and many other topics. The site is currently under development, but we have had significant interest from the community, and have a team of 19 EPO professionals and community volunteers from 14 different institutions signed up to contribute to the project. The STEMdex site can be found at stemdex.ipac.caltech.edu.

  12. Secondary analysis of large databases for hepatology research.

    PubMed

    Okafor, Philip N; Chiejina, Maria; de Pretis, Nicolo; Talwalkar, Jayant A

    2016-04-01

    Secondary analysis of large datasets involves the utilization of existing data that has typically been collected for other purposes to advance scientific knowledge. This is an established methodology applied in health services research with the unique advantage of efficiently identifying relationships between predictor and outcome variables but which has been underutilized for hepatology research. Our review of 1431 abstracts published in the 2013 European Association for the Study of Liver (EASL) abstract book showed that less than 0.5% of published abstracts utilized secondary analysis of large database methodologies. This review paper describes existing large datasets that can be exploited for secondary analyses in liver disease research. It also suggests potential questions that could be addressed using these data warehouses and highlights the strengths and limitations of each dataset as described by authors that have previously used them. The overall goal is to bring these datasets to the attention of readers and ultimately encourage the consideration of secondary analysis of large database methodologies for the advancement of hepatology. PMID:26739689

  13. 77 FR 66622 - Submission for OMB Review; Comment Request: National Database for Autism Research (NDAR) Data...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-06

    ... Database for Autism Research (NDAR) Data Access Request SUMMARY: Under the provisions of Section 3507(a)(1... control number. Proposed Collection: Title: National Database for Autism Research (NDAR) Data...

  14. Reconciling Teacher Unionism's Disparate Identities: A View from the Field. BCTF Research Report.

    ERIC Educational Resources Information Center

    Naylor, Charlie

    While traditional debates about teacher unions have focused on their dual roles (industrial and professional), this report suggests that such duality is outdated, and it is important to recognize that teacher unions in North America now focus on a multiplicity of areas. To understand them, it is necessary to analyze the range of teacher union…

  15. Navajo Participation in Labor Unions. Lake Powell Research Project Bulletin Number 15, December 1975.

    ERIC Educational Resources Information Center

    Robbins, Lynn A.

    Navajo participation in labor unions and Navajo labor relations have undergone rapid and fundamental changes since the development of industry around Lake Powell and on Black Mesa. Early attempts to unionize Navajo workers met with stiff resistance from employees and the Navajo Tribal Council. Union entry into the Navajo Reservation was viewed as…

  16. The FoodCast research image database (FRIDa)

    PubMed Central

    Foroni, Francesco; Pergola, Giulio; Argiris, Georgette; Rumiati, Raffaella I.

    2013-01-01

    In recent years we have witnessed an increasing interest in food processing and eating behaviors. This is probably due to several reasons. The biological relevance of food choices, the complexity of the food-rich environment in which we presently live (making food-intake regulation difficult), and the increasing health care cost due to illness associated with food (food hazards, food contamination, and aberrant food-intake). Despite the importance of the issues and the relevance of this research, comprehensive and validated databases of stimuli are rather limited, outdated, or not available for non-commercial purposes to independent researchers who aim at developing their own research program. The FoodCast Research Image Database (FRIDa) we present here includes 877 images belonging to eight different categories: natural-food (e.g., strawberry), transformed-food (e.g., french fries), rotten-food (e.g., moldy banana), natural-non-food items (e.g., pinecone), artificial food-related objects (e.g., teacup), artificial objects (e.g., guitar), animals (e.g., camel), and scenes (e.g., airport). FRIDa has been validated on a sample of healthy participants (N = 73) on standard variables (e.g., valence, familiarity, etc.) as well as on other variables specifically related to food items (e.g., perceived calorie content); it also includes data on the visual features of the stimuli (e.g., brightness, high frequency power, etc.). FRIDa is a well-controlled, flexible, validated, and freely available (http://foodcast.sissa.it/neuroscience/) tool for researchers in a wide range of academic fields and industry. PMID:23459781

  17. LLNL Middle East and North Africa research database

    SciTech Connect

    Ruppert, S.D.; Hauk, T.F.; Leach, R.

    1997-07-15

    The Lawrence Livermore National Laboratory (LLNL) CTBT R{ampersand}D program has made significant progress assembling a comprehensive seismic database (DB) for events and derived parameters in the Middle East and North Africa (ME/NA). The LLNL research DB provides not only a coherent framework in which store and organize large volumes of collected seismic waveforms and associated event parameter information but also provides an efficient data processing/research environment. The DB is designed to be flexible and extensible in order to accommodate the large volumes of data in diverse formats from many sources in addition to maintaining detailed quality control and metadata. Researchers can make use of the relational nature of the DB and interactive analysis tools to quickly and efficiently process large volumes of data. Seismic waveforms have been systematically collected form a wide range of local and regional networks using numerous earthquake bulletins and converted a common format based on CSS3.O while undergoing quality control and corrections of errors. By combining traveltime observations, event characterization studies, and regional wave-propagation studies of the LLNL CTBT team, we are assembling a library of ground truth information and event location correction surfaces required to support the ME/NA regionalization program. Corrections and parameters distilled from the LLNL research DB will provide needed contributions to the DOE knowledge base for the ME/NA region and enable the USNDC and IDC to effectively verify CTBT compliance.

  18. The potential of UK clinical databases in enhancing paediatric medication research

    PubMed Central

    Wong, Ian C K; Murray, Macey L

    2005-01-01

    The research potential of many UK clinical databases is not being realized. A recent report published by the Royal College of Paediatrics & Child Health stated that there is a need to build research capacity and support in the area of paediatric pharmacology, with specific emphasis on the use of clinical databases. This article presents the databases available in the UK for medication research and gives some examples of paediatric studies conducted. The databases discussed include the Prescription Pricing Authority database, the General Practice Research Database, IMS Health databases (Medical Data Index, MIDAS Prescribing Insights, Disease-Analyser-Mediplus) and the Yellow Card Scheme. Other databases such as the Medicines Monitoring Unit (MEMO) and the Scottish Primary Care Computer System also have research potential in paediatric pharmacoepidemiology, but their population sizes are relatively small. PMID:15948943

  19. EHME: a new word database for research in Basque language.

    PubMed

    Acha, Joana; Laka, Itziar; Landa, Josu; Salaburu, Pello

    2014-01-01

    This article presents EHME, the frequency dictionary of Basque structure, an online program that enables researchers in psycholinguistics to extract word and nonword stimuli, based on a broad range of statistics concerning the properties of Basque words. The database consists of 22.7 million tokens, and properties available include morphological structure frequency and word-similarity measures, apart from classical indexes: word frequency, orthographic structure, orthographic similarity, bigram and biphone frequency, and syllable-based measures. Measures are indexed at the lemma, morpheme and word level. We include reliability and validation analysis. The application is freely available, and enables the user to extract words based on concrete statistical criteria 1 , as well as to obtain statistical characteristics from a list of words PMID:26054360

  20. Forming a Research Question from a Multi-Center Database

    PubMed Central

    Likosky, Donald S.

    2009-01-01

    Abstract: It is not uncommon for individuals to ask biostatisiticians and epidemiologists to assist them with a research project. Often the request is in the shape of statistical analyses. However, most of these requests are nothing more than missed opportunities. This manuscript focuses on the reasons underlying such a statement. Most individuals might say that the most important aspect of a study is its conclusion. Many who would disagree with this sentiment and would feel that the most important aspect of a study rather is the question it intends to address. If this question is not articulated sufficiently, any additional information stemming from the study will most likely be irrelevant. Herein, some principles for formulating (successfully) a question from a multi-center database will be described. PMID:19361039

  1. A relational database management system for atmospheric compensation research

    NASA Astrophysics Data System (ADS)

    Powell, John; Erukulla, Gautami; Buhisi, Mohamad; Velauthapillai, Balendran

    2011-04-01

    Atmospheric compensation is a key step in the processing of most remotely sensed Earth images, but is particularly important in Hyperspectral Imagery (HSI) analysis. The state of atmospheric sensible variables at the time of the image is a key driver of atmospheric path radiance and transmissivity effects. A thorough assessment of the state of the atmosphere is rarely conducted in HSI analysis, however, even in rigorous scientific literature. This is due in part to the historical lack of meteorological data associated with imagery collects, and the difficulty in accessing and analyzing the data that is available. With the expanding availability of online climatological and observational atmospheric data and the advent of web enabled search and retrieval tools, easy access to worldwide atmospheric data relevant to atmospheric compensation is possible. In this project, a Relational Database Management System (RDBMS) is developed that automatically retrieves relevant atmospheric data from several online data stores based on input image metadata. The RBDMS provides researchers with a single, easily accessible repository of meteorological data to aid in researching atmospheric effects. System design considerations and available data sources are reviewed, and example research applications are presented.

  2. University Real Estate Development Database: A Database-Driven Internet Research Tool

    ERIC Educational Resources Information Center

    Wiewel, Wim; Kunst, Kara

    2008-01-01

    The University Real Estate Development Database is an Internet resource developed by the University of Baltimore for the Lincoln Institute of Land Policy, containing over six hundred cases of university expansion outside of traditional campus boundaries. The University Real Estate Development database is a searchable collection of real estate…

  3. University Real Estate Development Database: A Database-Driven Internet Research Tool

    ERIC Educational Resources Information Center

    Wiewel, Wim; Kunst, Kara

    2008-01-01

    The University Real Estate Development Database is an Internet resource developed by the University of Baltimore for the Lincoln Institute of Land Policy, containing over six hundred cases of university expansion outside of traditional campus boundaries. The University Real Estate Development database is a searchable collection of real estate…

  4. Learning and Adapting for Organisational Change: Researching Union Education in Australia

    ERIC Educational Resources Information Center

    Brown, Tony; Yasukawa, Keiko

    2010-01-01

    The last quarter century saw a restructuring of employment, production and trade and a dramatic decline in union membership and density levels. There are many explanations for this, including the hostile industrial relations framework imposed by many governments, but there have been other factors such as the growth of new non-unionized industries…

  5. Learning and Adapting for Organisational Change: Researching Union Education in Australia

    ERIC Educational Resources Information Center

    Brown, Tony; Yasukawa, Keiko

    2010-01-01

    The last quarter century saw a restructuring of employment, production and trade and a dramatic decline in union membership and density levels. There are many explanations for this, including the hostile industrial relations framework imposed by many governments, but there have been other factors such as the growth of new non-unionized industries…

  6. HOWDY: an integrated database system for human genome research

    PubMed Central

    Hirakawa, Mika

    2002-01-01

    HOWDY is an integrated database system for accessing and analyzing human genomic information (http://www-alis.tokyo.jst.go.jp/HOWDY/). HOWDY stores information about relationships between genetic objects and the data extracted from a number of databases. HOWDY consists of an Internet accessible user interface that allows thorough searching of the human genomic databases using the gene symbols and their aliases. It also permits flexible editing of the sequence data. The database can be searched using simple words and the search can be restricted to a specific cytogenetic location. Linear maps displaying markers and genes on contig sequences are available, from which an object can be chosen. Any search starting point identifies all the information matching the query. HOWDY provides a convenient search environment of human genomic data for scientists unsure which database is most appropriate for their search. PMID:11752279

  7. Database security and encryption technology research and application

    NASA Astrophysics Data System (ADS)

    Zhu, Li-juan

    2013-03-01

    The main purpose of this paper is to discuss the current database information leakage problem, and discuss the important role played by the message encryption techniques in database security, As well as MD5 encryption technology principle and the use in the field of website or application. This article is divided into introduction, the overview of the MD5 encryption technology, the use of MD5 encryption technology and the final summary. In the field of requirements and application, this paper makes readers more detailed and clearly understood the principle, the importance in database security, and the use of MD5 encryption technology.

  8. Developing the agenda for European Union collaboration on non-communicable diseases research in Sub-Saharan Africa

    PubMed Central

    2010-01-01

    Background Health research is increasing in Africa, but most resources are currently chanelled towards infectious diseases and health system development. While infectious diseases remain a heavy burden for some African countries, non-communicable diseases (NCDs) account for more than half of all deaths globally and WHO predicts 27% increase in NCDs in Africa over the next decade. We present findings of a European-Africa consultation on the research agenda for NCDs. Methods A workshop was held in Yaoundé, Cameroon, organized by the Network for the Coordination and Advancement of Sub-Saharan Africa-European Union Science and Technology Cooperation (CAAST-Net). Drawing on initial presentations, a small expert group from academic, clinical, public-health and administrative positions considered research needs in Africa for cardiovascular disease, cancer and diabetes. Results Research in Africa can draw from different environmental and genetic characteristics to understand the causes of the disease, while economic and social factors are important in developing relevant strategies for prevention and treatment. The suggested research needs include better methods for description and recording, clinical studies, understanding cultural impacts, prevention strategies, and the integrated organisation of care. Specific fields proposed for research are listed. Conclusions Our paper contributes to transparency in the process of priority-setting for health research in Africa. Although the European Union Seventh Framework Research Programme prioritises biomedical and clinical research, research for Africa should also address broader social and cultural research and intervention research for greatest impact. Research policy leaders in Africa must engage national governments and international agencies as well as service providers and research communities. None can act effectively alone. Bringing together the different stakeholders, and feeding the results through to the European Union research programme is a valuable contribution of CAAST-Net. PMID:20482860

  9. Rap System of Stress Stimulation Can Promote Bone Union after Lower Tibial Bone Fracture: A Clinical Research

    PubMed Central

    YAO, Jian-fei; SHEN, Jia-zuo; LI, Da-kun; LIN, Da-sheng; Li, Lin; LI, Qiang; Qi, Peng; LIAN, Ke-jian; DING, Zhen-qi

    2012-01-01

    Background Lower tibial bone fracture may easily cause bone delayed union or nonunion because of lacking of dynamic mechanical load. Objective Research Group would design a new instrument as Rap System of Stress Stimulation (RSSS) to provide dynamic mechanical load which would promote lower tibial bone union postoperatively. Methods This clinical research was conducted from January 2008 to December 2010, 92 patients(male 61/female 31, age 16-70years, mean 36.3years) who suffered lower tibial bone closed fracture were given intramedullary nail fixation and randomly averagely separated into experimental group and control group(according to the successively order when patients went for the admission procedure). Then researchers analysed the clinical healing time, full weight bearing time, VAS (Visual Analogue Scales) score and callus growth score of Lane-Sandhu in 3,6,12 months postoperatively. The delayed union and nonunion rates were compared at 6 and 12 months separately. Results All the 92 patients had been followed up (mean 14 months). Clinical bone healing time in experimental group was 88.78±8.80 days but control group was 107.91±9.03days. Full weight bearing time in experimental group was 94.07±9.81 days but control group was 113.24±13.37 days respectively (P<0.05). The delayed union rate in 6 months was 4.3% in experimental group but 10.9% in control group(P<0.05). The nonunion rate in 12 months was 6.5% in experimental group but 19.6% in control group(P<0.05). In 3, 6, 12 months postoperatively, VAS score and Lane-Sandhu score in experimental group had more significantly difference than them in control group. Conclusions RSSS can intermittently provide dynamic mechanical load and stimulate callus formation, promote lower tibial bone union, reduce bone delayed union or nonunion rate. It is an adjuvant therapy for promoting bone union after lower tibial bone fracture. PMID:22859907

  10. The opportunities and obstacles in developing a vascular birthmark database for clinical and research use

    PubMed Central

    Sharma, Vishal K; Fraulin, Frankie OG; Harrop, A Robertson; McPhalen, Donald F

    2011-01-01

    INTRODUCTION Databases are useful tools in clinical settings. The authors review the benefits and challenges associated with the development and implementation of an efficient electronic database for the multidisciplinary Vascular Birthmark Clinic at the Alberta Children’s Hospital, Calgary, Alberta. METHODS The content and structure of the database were designed using the technical expertise of a data analyst from the Calgary Health Region. Relevant clinical and demographic data fields were included with the goal of documenting ongoing care of individual patients, and facilitating future epidemiological studies of this patient population. After completion of this database, 10 challenges encountered during development were retrospectively identified. Practical solutions for these challenges are presented. RESULTS The challenges identified during the database development process included: identification of relevant data fields; balancing simplicity and user-friendliness with complexity and comprehensive data storage; database expertise versus clinical expertise; software platform selection; linkage of data from the previous spreadsheet to a new data management system; ethics approval for the development of the database and its utilization for research studies; ensuring privacy and limited access to the database; integration of digital photographs into the database; adoption of the database by support staff in the clinic; and maintaining up-to-date entries in the database. CONCLUSIONS There are several challenges involved in the development of a useful and efficient clinical database. Awareness of these potential obstacles, in advance, may simplify the development of clinical databases by others in various surgical settings. PMID:23204881

  11. An integrated database to support research on Escherichia coli

    SciTech Connect

    Baehr, A.; Dunham, G.; Matsuda, Hideo; Michaels, G.; Taylor, R.; Overbeek, R.; Rudd, K.E. ); Ginsburg, A.; Joerg, D.; Kazic, T. . Dept. of Genetics); Hagstrom, R.; Zawada, D. ); Smith, C.; Yoshida, Kaoru )

    1992-01-01

    We have used logic programming to design and implement a prototype database of genomic information for the model bacterial organism Escherichia coli. This report presents the fundamental database primitives that can be used to access and manipulate data relating to the E. coli genome. The present system, combined with a tutorial manual, provides immediate access to the integrated knowledge base for E. coli chromosome data. It also serves as the foundation for development of more user-friendly interfaces that have the same retrieval power and high-level tools to analyze complex chromosome organization.

  12. Chinese villages and their sustainable future: the European Union-China-Research Project "SUCCESS".

    PubMed

    Dumreicher, Heidi

    2008-04-01

    China has 800,000 villages-one person out of seven on the globe is living in a Chinese rural settlement. Yet the global discussions about the situation in China is currently characterised by a disproportionate focus on the development of towns and until now circumstances have generally been neglected in the rural areas, where 70% of the Chinese population is still living. Within the 5 years of the SUCCESS project research, this set of actual problems has been considered and analysed under the principle of sustainability: "What to maintain?" "What to change?" were the overall research questions asked in the SUCCESS project; the researchers were looking for answers under a sustainability regime, respecting the need to raise the quality of life in the villages. Several interweaving processes were used to achieve results: the inter-disciplinary research process between many areas of expertise, the trans-disciplinary process between the researchers and the Chinese villagers, and a negotiation process that made the connection between these two processes. The introduction describes the basic sustainability definition that was orienting the whole study. The innovation lays mostly in the methodology: the inter-disciplinary research co-operation related to practice and to involving the affected communities is needed to manage the significant and growing imbalances between urban and rural areas regarding their sustainability. In the transdisciplinary work, the project developed "village future sentences" that describe the local outcome of the research as one step towards better theoretical understanding of the mechanisms that could lead to a sustainable future, and they also managed to start sustainability processes in the case study sites. The integrated approach of the project helped generating future scenarios for these villages covering all aspects of their development, including urban design issues. Out of these scenarios, the villages developed small projects that could be implemented during the research period. This work made an important impact on community thinking within these villages. However, it can also be seen as contributing to the dramatically changing development process in China, by finding a balance between traditional and contemporary approaches. In particular, the approach demonstrated a new, inter-disciplinary and trans-disciplinary negotiation processes whereby the local knowledge and the expert knowledge find common ground and outcomes. The article follows the hypothesis that only comprehensive concepts can contribute to an upgraded living standard, where living spaces and rural life should be recognised and esteemed in the future as a complement to urban lifestyles within the Chinese society. Innovative knowledge generation-such as the "systemic structure constellation" technique or the systems model approach-helped to bring out latent needs, hopes and potential of the villagers. Besides the practical usage of these implemented projects, the process leading there showed the stakeholders their own fields of action. One major impact of these projects is the visibility of the results, which is crucial for villagers' awareness, their self-confidence and their experience with a successful participation in decision-making processes. Another impact is the potential for replicating results of sustainability-oriented patterns throughout China, especially as three of the villages have been nominated official model villages. Scenarios of a sustainable future for Chinese villages were the objective of the SUCCESS project. The first condition for this future is the question whether they can persist into the future-and to picture the importance of the rural environment and living space as a relevant element of Chinese life that needs to get a better image and more attention from the authorities and from the public opinion. Therefore, the final sentence that the whole research consortium, composed of 17 scientific institutions from European Union and China, agreed upon as a common

  13. The Technology Education Graduate Research Database, 1892-2000. CTTE Monograph.

    ERIC Educational Resources Information Center

    Reed, Philip A., Ed.

    The Technology Education Graduate Research Database (TEGRD) was designed in two parts. The first part was a 384 page bibliography of theses and dissertations from 1892-2000. The second part was an online, searchable database of graduate research completed within technology education from 1892 to the present. The primary goals of the project were:…

  14. European Union Students Studying in English Higher Education Institutions. DIUS Research Report 08-09

    ERIC Educational Resources Information Center

    Morris, Marian; Rutt, Simon

    2008-01-01

    This study aimed to identify the pathways, intentions and relevant perceptions of (non-UK) European Union (EU) students entering English higher education. It sought to identify why students wished to obtain an English HE qualification, their attitudes towards the uptake and repayment of tuition fee loans and their future career plans. Drawing on…

  15. A Multilateral Use and Processing of A Large Bibliographic Database for Research Information

    NASA Astrophysics Data System (ADS)

    Konishi, Osamu; Obayashi, Haruo

    In order to explain the multilateral use of bibliographic database in research activities, nuclear fusion research field as the comprehensive science was selected. The processing method of the above mentioned database is mainly described. Considering advantages of the bibliographic and indexed information of such database, its use is classified into three types: 1. To use for reference information, 2. To obtain facts and knowledge from information, and 3. To process and analyse information. Each sample corresponding to the above is introduced as follows, and the usefulness of a large scale database is made clear. 1) Use of online search in research activities, 2) Construction of scientific terms list utilizing keywords and their frequency in the database, and 3) To analyse bibliographic information metrically and evaluate research. This is an application of scientometrics.

  16. SHIELD: an integrative gene expression database for inner ear research

    PubMed Central

    Shen, Jun; Scheffer, Déborah I.; Kwan, Kelvin Y.; Corey, David P.

    2015-01-01

    The inner ear is a highly specialized mechanosensitive organ responsible for hearing and balance. Its small size and difficulty in harvesting sufficient tissue has hindered the progress of molecular studies. The protein components of mechanotransduction, the molecular biology of inner ear development and the genetic causes of many hereditary hearing and balance disorders remain largely unknown. Inner-ear gene expression data will help illuminate each of these areas. For over a decade, our laboratories and others have generated extensive sets of gene expression data for different cell types in the inner ear using various sample preparation methods and high-throughput genome-wide approaches. To facilitate the study of genes in the inner ear by efficient presentation of the accumulated data and to foster collaboration among investigators, we have developed the Shared Harvard Inner Ear Laboratory Database (SHIELD), an integrated resource that seeks to compile, organize and analyse the genomic, transcriptomic and proteomic knowledge of the inner ear. Five datasets are currently available. These datasets are combined in a relational database that integrates experimental data and annotations relevant to the inner ear. The SHIELD has a searchable web interface with two data retrieval options: viewing the gene pages online or downloading individual datasets as data tables. Each retrieved gene page shows the gene expression data and detailed gene information with hyperlinks to other online databases with up-to-date annotations. Downloadable data tables, for more convenient offline data analysis, are derived from publications and are current as of the time of publication. The SHIELD has made published and some unpublished data freely available to the public with the hope and expectation of accelerating discovery in the molecular biology of balance, hearing and deafness. Database URL: https://shield.hms.harvard.edu PMID:26209310

  17. Union Rights.

    ERIC Educational Resources Information Center

    Goodwin, Harold I.

    1977-01-01

    Collective bargaining is intended to define what constitutes faculty union rights. Union claims to rights must be based on the content of the Agreement. Several union rights negotiated by faculty organizations with college and university administrations are detailed. These include agreements on who manages internal union affairs; rights that…

  18. SHIELD: an integrative gene expression database for inner ear research.

    PubMed

    Shen, Jun; Scheffer, Déborah I; Kwan, Kelvin Y; Corey, David P

    2015-01-01

    The inner ear is a highly specialized mechanosensitive organ responsible for hearing and balance. Its small size and difficulty in harvesting sufficient tissue has hindered the progress of molecular studies. The protein components of mechanotransduction, the molecular biology of inner ear development and the genetic causes of many hereditary hearing and balance disorders remain largely unknown. Inner-ear gene expression data will help illuminate each of these areas. For over a decade, our laboratories and others have generated extensive sets of gene expression data for different cell types in the inner ear using various sample preparation methods and high-throughput genome-wide approaches. To facilitate the study of genes in the inner ear by efficient presentation of the accumulated data and to foster collaboration among investigators, we have developed the Shared Harvard Inner Ear Laboratory Database (SHIELD), an integrated resource that seeks to compile, organize and analyse the genomic, transcriptomic and proteomic knowledge of the inner ear. Five datasets are currently available. These datasets are combined in a relational database that integrates experimental data and annotations relevant to the inner ear. The SHIELD has a searchable web interface with two data retrieval options: viewing the gene pages online or downloading individual datasets as data tables. Each retrieved gene page shows the gene expression data and detailed gene information with hyperlinks to other online databases with up-to-date annotations. Downloadable data tables, for more convenient offline data analysis, are derived from publications and are current as of the time of publication. The SHIELD has made published and some unpublished data freely available to the public with the hope and expectation of accelerating discovery in the molecular biology of balance, hearing and deafness. PMID:26209310

  19. Development and Validation of Army Selection and Classification Measures. Project A: Longitudinal Research Database Plan. Research Report 1356.

    ERIC Educational Resources Information Center

    Wise, Lauress L.; And Others

    This report describes plans for the development of a major longitudinal research database designed to support the development and validation of new predictors of Army performance, and also new measures of Army performance against which the new predictors can be validated. The following aspects of the database are addressed: (1) the anticipated…

  20. Design Considerations for a Web-based Database System of ELISpot Assay in Immunological Research

    PubMed Central

    Ma, Jingming; Mosmann, Tim; Wu, Hulin

    2005-01-01

    The enzyme-linked immunospot (ELISpot) assay has been a primary means in immunological researches (such as HIV-specific T cell response). Due to huge amount of data involved in ELISpot assay testing, the database system is needed for efficient data entry, easy retrieval, secure storage, and convenient data process. Besides, the NIH has recently issued a policy to promote the sharing of research data (see http://grants.nih.gov/grants/policy/data_sharing). The Web-based database system will be definitely benefit to data sharing among broad research communities. Here are some considerations for a database system of ELISpot assay (DBSEA). PMID:16779326

  1. USDA food and nutrient databases provide the infrastructure for food and nutrition research, policy and practice

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The USDA food and nutrient databases provide the basic infrastructure for food and nutrition research, nutrition monitoring, and dietary practice. They have had a long history that goes back to 1892, and are unique, as they are the only databases available in the public domain that perform these fu...

  2. Open-Access Metabolomics Databases for Natural Product Research: Present Capabilities and Future Potential

    PubMed Central

    Johnson, Sean R.; Lange, Bernd Markus

    2015-01-01

    Various databases have been developed to aid in assigning structures to spectral peaks observed in metabolomics experiments. In this review article, we discuss the utility of currently available open-access spectral and chemical databases for natural products discovery. We also provide recommendations on how the research community can contribute to further improvements. PMID:25789275

  3. Data-Base and Online System Usage in a For-Profit General Research Environment.

    ERIC Educational Resources Information Center

    Basch, Reva

    1985-01-01

    Describes Information on Demand, an information broker that provides database and manual research on a fee for service basis, and accesses more than a dozen online systems. Relative strengths and weaknesses of particular systems and the criteria used to select databases and online vendors are identified and discussed. (CLB)

  4. The Use of a Relational Database in Qualitative Research on Educational Computing.

    ERIC Educational Resources Information Center

    Winer, Laura R.; Carriere, Mario

    1990-01-01

    Discusses the use of a relational database as a data management and analysis tool for nonexperimental qualitative research, and describes the use of the Reflex Plus database in the Vitrine 2001 project in Quebec to study computer-based learning environments. Information systems are also discussed, and the use of a conceptual model is explained.…

  5. The Beltsville Human Nutrition Research Center's Porcine Immunology and Nutrition Resource Database

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Several diverse genomics-based databases have developed to facilitate research with human and rodent models. Current porcine gene databases, however, lack the nutritional and immunological orientation and robust annotation to design effective molecular tools to study relevant pig models. To address ...

  6. Patient Confidentiality in the Research Use of Clinical Medical Databases

    PubMed Central

    Krishna, Rajeev; Kelleher, Kelly; Stahlberg, Eric

    2007-01-01

    Electronic medical record keeping has led to increased interest in analyzing historical patient data to improve care delivery. Such research use of patient data, however, raises concerns about confidentiality and institutional liability. Institutional review boards must balance patient data security with a researcher’s ability to explore potentially important clinical relationships. We considered the issues involved when patient records from health care institutions are used in medical research. We also explored current regulations on patient confidentiality, the need for identifying information in research, and the effectiveness of deidentification and data security. We will present an algorithm for researchers to use to think about the data security needs of their research, and we will introduce a vocabulary for documenting these techniques in proposals and publications. PMID:17329644

  7. Nigeria Anopheles Vector Database: An Overview of 100 Years' Research

    PubMed Central

    Okorie, Patricia Nkem; McKenzie, F. Ellis; Ademowo, Olusegun George; Bockarie, Moses; Kelly-Hope, Louise

    2011-01-01

    Anopheles mosquitoes are important vectors of malaria and lymphatic filariasis (LF), which are major public health diseases in Nigeria. Malaria is caused by infection with a protozoan parasite of the genus Plasmodium and LF by the parasitic worm Wuchereria bancrofti. Updating our knowledge of the Anopheles species is vital in planning and implementing evidence based vector control programs. To present a comprehensive report on the spatial distribution and composition of these vectors, all published data available were collated into a database. Details recorded for each source were the locality, latitude/longitude, time/period of study, species, abundance, sampling/collection methods, morphological and molecular species identification methods, insecticide resistance status, including evidence of the kdr allele, and P. falciparum sporozoite rate and W. bancrofti microfilaria prevalence. This collation resulted in a total of 110 publications, encompassing 484,747 Anopheles mosquitoes in 632 spatially unique descriptions at 142 georeferenced locations being identified across Nigeria from 1900 to 2010. Overall, the highest number of vector species reported included An. gambiae complex (65.2%), An. funestus complex (17.3%), An. gambiae s.s. (6.5%). An. arabiensis (5.0%) and An. funestus s.s. (2.5%), with the molecular forms An. gambiae M and S identified at 120 locations. A variety of sampling/collection and species identification methods were used with an increase in molecular techniques in recent decades. Insecticide resistance to pyrethroids and organochlorines was found in the main Anopheles species across 45 locations. Presence of P. falciparum and W. bancrofti varied between species with the highest sporozoite rates found in An. gambiae s.s, An. funestus s.s. and An. moucheti, and the highest microfilaria prevalence in An. gambiae s.l., An. arabiensis, and An. gambiae s.s. This comprehensive geo-referenced database provides an essential baseline on Anopheles vectors and will be an important resource for malaria and LF vector control programmes in Nigeria. PMID:22162764

  8. Healthcare Databases in Thailand and Japan: Potential Sources for Health Technology Assessment Research

    PubMed Central

    Saokaew, Surasak; Sugimoto, Takashi; Kamae, Isao; Pratoomsoot, Chayanin; Chaiyakunapruk, Nathorn

    2015-01-01

    Background Health technology assessment (HTA) has been continuously used for value-based healthcare decisions over the last decade. Healthcare databases represent an important source of information for HTA, which has seen a surge in use in Western countries. Although HTA agencies have been established in Asia-Pacific region, application and understanding of healthcare databases for HTA is rather limited. Thus, we reviewed existing databases to assess their potential for HTA in Thailand where HTA has been used officially and Japan where HTA is going to be officially introduced. Method Existing healthcare databases in Thailand and Japan were compiled and reviewed. Databases’ characteristics e.g. name of database, host, scope/objective, time/sample size, design, data collection method, population/sample, and variables were described. Databases were assessed for its potential HTA use in terms of safety/efficacy/effectiveness, social/ethical, organization/professional, economic, and epidemiological domains. Request route for each database was also provided. Results Forty databases– 20 from Thailand and 20 from Japan—were included. These comprised of national censuses, surveys, registries, administrative data, and claimed databases. All databases were potentially used for epidemiological studies. In addition, data on mortality, morbidity, disability, adverse events, quality of life, service/technology utilization, length of stay, and economics were also found in some databases. However, access to patient-level data was limited since information about the databases was not available on public sources. Conclusion Our findings have shown that existing databases provided valuable information for HTA research with limitation on accessibility. Mutual dialogue on healthcare database development and usage for HTA among Asia-Pacific region is needed. PMID:26560127

  9. Landslide databases for applied landslide impact research: the example of the landslide database for the Federal Republic of Germany

    NASA Astrophysics Data System (ADS)

    Damm, Bodo; Klose, Martin

    2014-05-01

    This contribution presents an initiative to develop a national landslide database for the Federal Republic of Germany. It highlights structure and contents of the landslide database and outlines its major data sources and the strategy of information retrieval. Furthermore, the contribution exemplifies the database potentials in applied landslide impact research, including statistics of landslide damage, repair, and mitigation. The landslide database offers due to systematic regional data compilation a differentiated data pool of more than 5,000 data sets and over 13,000 single data files. It dates back to 1137 AD and covers landslide sites throughout Germany. In seven main data blocks, the landslide database stores besides information on landslide types, dimensions, and processes, additional data on soil and bedrock properties, geomorphometry, and climatic or other major triggering events. A peculiarity of this landslide database is its storage of data sets on land use effects, damage impacts, hazard mitigation, and landslide costs. Compilation of landslide data is based on a two-tier strategy of data collection. The first step of information retrieval includes systematic web content mining and exploration of online archives of emergency agencies, fire and police departments, and news organizations. Using web and RSS feeds and soon also a focused web crawler, this enables effective nationwide data collection for recent landslides. On the basis of this information, in-depth data mining is performed to deepen and diversify the data pool in key landslide areas. This enables to gather detailed landslide information from, amongst others, agency records, geotechnical reports, climate statistics, maps, and satellite imagery. Landslide data is extracted from these information sources using a mix of methods, including statistical techniques, imagery analysis, and qualitative text interpretation. The landslide database is currently migrated to a spatial database system running on PostgreSQL/PostGIS. This provides advanced functionality for spatial data analysis and forms the basis for future data provision and visualization using a WebGIS application. Analysis of landslide database contents shows that in most parts of Germany landslides primarily affect transportation infrastructures. Although with distinct lower frequency, recent landslides are also recorded to cause serious damage to hydraulic facilities and waterways, supply and disposal infrastructures, sites of cultural heritage, as well as forest, agricultural, and mining areas. The main types of landslide damage are failure of cut and fill slopes, destruction of retaining walls, street lights, and forest stocks, burial of roads, backyards, and garden areas, as well as crack formation in foundations, sewer lines, and building walls. Landslide repair and mitigation at transportation infrastructures is dominated by simple solutions such as catch barriers or rock fall drapery. These solutions are often undersized and fail under stress. The use of costly slope stabilization or protection systems is proven to reduce these risks effectively over longer maintenance cycles. The right balancing of landslide mitigation is thus a crucial problem in managing landslide risks. Development and analysis of such landslide databases helps to support decision-makers in finding efficient solutions to minimize landslide risks for human beings, infrastructures, and financial assets.

  10. A Temporal Abstraction-based Extract, Transform and Load Process for Creating Registry Databases for Research

    PubMed Central

    Post, Andrew; Kurc, Tahsin; Overcash, Marc; Cantrell, Dedra; Morris, Tim; Eckerson, Kristi; Tsui, Circe; Willey, Terry; Quyyumi, Arshed; Eapen, Danny; Umpierrez, Guillermo; Ziemer, David; Saltz, Joel

    2011-01-01

    In the CTSA era there is great interest in aggregating and comparing populations across institutions. These sites likely represent data differently in their clinical data warehouses and other databases. Clinical data warehouses frequently are structured in a generalized way that supports many constituencies. For research, there is a need to transform these heterogeneous data into a shared representation, and to perform categorization and interpretation to optimize the data representation for investigators. We are addressing this need by extending an existing temporal abstraction-based clinical database query system, PROTEMPA. The extended system allows specifying data types of interest in federated databases, extracting the data into a shared representation, transforming it through categorization and interpretation, and loading it into a registry database that can be refreshed. Such a registry’s access control, data representation and query tools can be tailored to the needs of research while keeping local databases as the source of truth. PMID:22211179

  11. A Temporal Abstraction-based Extract, Transform and Load Process for Creating Registry Databases for Research.

    PubMed

    Post, Andrew; Kurc, Tahsin; Overcash, Marc; Cantrell, Dedra; Morris, Tim; Eckerson, Kristi; Tsui, Circe; Willey, Terry; Quyyumi, Arshed; Eapen, Danny; Umpierrez, Guillermo; Ziemer, David; Saltz, Joel

    2011-01-01

    In the CTSA era there is great interest in aggregating and comparing populations across institutions. These sites likely represent data differently in their clinical data warehouses and other databases. Clinical data warehouses frequently are structured in a generalized way that supports many constituencies. For research, there is a need to transform these heterogeneous data into a shared representation, and to perform categorization and interpretation to optimize the data representation for investigators. We are addressing this need by extending an existing temporal abstraction-based clinical database query system, PROTEMPA. The extended system allows specifying data types of interest in federated databases, extracting the data into a shared representation, transforming it through categorization and interpretation, and loading it into a registry database that can be refreshed. Such a registry's access control, data representation and query tools can be tailored to the needs of research while keeping local databases as the source of truth. PMID:22211179

  12. Impact of IPAD on CAD/CAM database university research

    NASA Technical Reports Server (NTRS)

    Leach, L. M.; Wozny, M. J.

    1984-01-01

    IPAD program has provided direction, focus and software products which impacted on CAD/CAM data base research and follow-on research. The relationship of IPAD to the research projects which involve the storage of geometric data in common data ase facilities such as data base machines, the exchange of data between heterogeneous data bases, the development of IGES processors, the migration of lrge CAD/CAM data base management systems to noncompatible hosts, and the value of RIM as a research tool is described.

  13. Security and health research databases: the stakeholders and questions to be addressed.

    PubMed

    Stewart, Sara

    2006-01-01

    Health research database security issues abound. Issues include subject confidentiality, data ownership, data integrity and data accessibility. There are also various stakeholders in database security. Each of these stakeholders has a different set of concerns and responsibilities when dealing with security issues. There is an obvious need for training in security issues, so that these issues may be addressed and health research will move on without added obstacles based on misunderstanding security methods and technologies. PMID:17238731

  14. Security and Health Research Databases: The Stakeholders and Questions to Be Addressed

    PubMed Central

    Stewart, Sara

    2006-01-01

    Health research database security issues abound. Issues include subject confidentiality, data ownership, data integrity and data accessibility. There are also various stakeholders in database security. Each of these stakeholders has a different set of concerns and responsibilities when dealing with security issues. There is an obvious need for training in security issues, so that these issues may be addressed and health research will move on without added obstacles based on misunderstanding security methods and technologies. PMID:17238731

  15. Standardizing Terminology and Definitions of Medication Adherence and Persistence in Research employing Electronic Databases

    PubMed Central

    Raebel, Marsha A.; Schmittdiel, Julie; Karter, Andrew J.; Konieczny, Jennifer L.; Steiner, John F.

    2013-01-01

    Objective To propose a unifying set of definitions for prescription adherence research utilizing electronic health record prescribing databases, prescription dispensing databases, and pharmacy claims databases and to provide a conceptual framework to operationalize these definitions consistently across studies. Methods We reviewed recent literature to identify definitions in electronic database studies of prescription-filling patterns for chronic oral medications. We then develop a conceptual model and propose standardized terminology and definitions to describe prescription-filling behavior from electronic databases. Results The conceptual model we propose defines two separate constructs: medication adherence and persistence. We define primary and secondary adherence as distinct sub-types of adherence. Metrics for estimating secondary adherence are discussed and critiqued, including a newer metric (New Prescription Medication Gap measure) that enables estimation of both primary and secondary adherence. Discussion Terminology currently used in prescription adherence research employing electronic databases lacks consistency. We propose a clear, consistent, broadly applicable conceptual model and terminology for such studies. The model and definitions facilitate research utilizing electronic medication prescribing, dispensing, and/or claims databases and encompasses the entire continuum of prescription-filling behavior. Conclusion Employing conceptually clear and consistent terminology to define medication adherence and persistence will facilitate future comparative effectiveness research and meta-analytic studies that utilize electronic prescription and dispensing records. PMID:23774515

  16. How can the research potential of the clinical quality databases be maximized? The Danish experience.

    PubMed

    Nørgaard, M; Johnsen, S P

    2016-02-01

    In Denmark, the need for monitoring of clinical quality and patient safety with feedback to the clinical, administrative and political systems has resulted in the establishment of a network of more than 60 publicly financed nationwide clinical quality databases. Although primarily devoted to monitoring and improving quality of care, the potential of these databases as data sources in clinical research is increasingly being recognized. In this review, we describe these databases focusing on their use as data sources for clinical research, including their strengths and weaknesses as well as future concerns and opportunities. The research potential of the clinical quality databases is substantial but has so far only been explored to a limited extent. Efforts related to technical, legal and financial challenges are needed in order to take full advantage of this potential. PMID:26785952

  17. Generation of comprehensive thoracic oncology database--tool for translational research.

    PubMed

    Surati, Mosmi; Robinson, Matthew; Nandi, Suvobroto; Faoro, Leonardo; Demchuk, Carley; Kanteti, Rajani; Ferguson, Benjamin; Gangadhar, Tara; Hensing, Thomas; Hasina, Rifat; Husain, Aliya; Ferguson, Mark; Karrison, Theodore; Salgia, Ravi

    2011-01-01

    The Thoracic Oncology Program Database Project was created to serve as a comprehensive, verified, and accessible repository for well-annotated cancer specimens and clinical data to be available to researchers within the Thoracic Oncology Research Program. This database also captures a large volume of genomic and proteomic data obtained from various tumor tissue studies. A team of clinical and basic science researchers, a biostatistician, and a bioinformatics expert was convened to design the database. Variables of interest were clearly defined and their descriptions were written within a standard operating manual to ensure consistency of data annotation. Using a protocol for prospective tissue banking and another protocol for retrospective banking, tumor and normal tissue samples from patients consented to these protocols were collected. Clinical information such as demographics, cancer characterization, and treatment plans for these patients were abstracted and entered into an Access database. Proteomic and genomic data have been included in the database and have been linked to clinical information for patients described within the database. The data from each table were linked using the relationships function in Microsoft Access to allow the database manager to connect clinical and laboratory information during a query. The queried data can then be exported for statistical analysis and hypothesis generation. PMID:21304468

  18. Multidimensional Mapping of Libraries Based on Shared Holdings in the OCLC Online Union Catalog. Research Report.

    ERIC Educational Resources Information Center

    McGrath, William E.; Hickey, Thomas B.

    This report describes the multidimensional scaling (MDS) method for interpreting collection overlap based on the number of books held by pairs of libraries in large groups (as many as 100 libraries or more). MDS results for four groups of libraries sampled from the OCLC database are also presented. MDS is described as a class of data-analytic or…

  19. Development of an HIV clinical and research database for South Africa.

    PubMed

    Kanter, A S; Spencer, D C; Steinberg, M H

    1997-02-01

    Health service restructuring in South Africa provides an opportunity to introduce appropriate Health Information System (HIS) technology. This is particularly relevant given the emerging HIV epidemic and the need to capture, translate and disseminate new experiences in HIV/AIDS care, support and clinical research. In 1994, a number of clinicians and health-care providers working in South Africa had begun to establish basic computerized databases to assist in research on HIV, but no standardized nomenclature or framework for collaboration was created. This paper describes a clinical and research database that could be used as an example for a standardized system by clinicians working in South Africa. The authors, with assistance from the National AIDS Research Programme of the Medical Research Council, created a prototype relational database using Microsoft Access. To test the prototype, 1057 HIV-positive patients from the infectious Disease Clinic at Johannesburg General Hospital were entered. PMID:9242014

  20. Ophthalmology and vision science research: part 5: surfing or sieving--using literature databases wisely.

    PubMed

    Sherwin, Trevor; Gilhotra, Amardeep K

    2006-02-01

    Literature databases are an ever-expanding resource available to the field of medical sciences. Understanding how to use such databases efficiently is critical for those involved in research. However, for the uninitiated, getting started is a major hurdle to overcome and for the occasional user, the finer points of database searching remain an unacquired skill. In the fifth and final article in this series aimed at those embarking on ophthalmology and vision science research, we look at how the beginning researcher can start to use literature databases and, by using a stepwise approach, how they can optimize their use. This instructional paper gives a hypothetical example of a researcher writing a review article and how he or she acquires the necessary scientific literature for the article. A prototype search of the Medline database is used to illustrate how even a novice might swiftly acquire the skills required for a medium-level search. It provides examples and key tips that can increase the proficiency of the occasional user. Pitfalls of database searching are discussed, as are the limitations of which the user should be aware. PMID:16565013

  1. [Research on the performance comparing and building of affective computing database based on physiological parameters].

    PubMed

    Li, Xin; Du, Xiaojuan; Zhang, Yunpeng; Ying, Lijuan; Li, Changwuz

    2014-08-01

    The validity and reasonableness of emotional data are the key issues in the cognitive affective computing research. Effects of the emotion recognition are decided by the quality of selected data directly. Therefore, it is an important part of affective computing research to build affective computing database with good performance, so that it is the hot spot of research in this field. In this paper, the performance of two classical cognitive affective computing databases, the Massachusetts Institute of Technology (MIT) cognitive affective computing database and Germany Augsburg University emotion recognition database were compared, their data structure and data types were compared respectively, and emotional recognition effect based on the data were studied comparatively. The results indicated that the analysis based on the physical parameters could get the effective emotional recognition, and would be a feasible method of pressure emotional evaluation. Because of the lack of stress emotional evaluation data based on the physiological parameters domestically, there is not a public stress emotional database. We hereby built a dataset for the stress evaluation towards the high stress group in colleges, candidates of postgraduates of Ph. D and master as the subjects. We then acquired their physiological parameters, and performed the pressure analysis based on this database. The results indicated that this dataset had a certain reference value for the stress evaluation, and we hope this research can provide a reference and support for emotion evaluation and analysis. PMID:25508418

  2. [Research on the performance comparing and building of affective computing database based on physiological parameters].

    PubMed

    Li, Xin; Du, Xiaojuan; Zhang, Yunpeng; Ying, Lijuan; Li, Changwuz

    2014-08-01

    The validity and reasonableness of emotional data are the key issues in the cognitive affective computing research. Effects of the emotion recognition are decided by the quality of selected data directly. Therefore, it is an important part of affective computing research to build affective computing database with good performance, so that it is the hot spot of research in this field. In this paper, the performance of two classical cognitive affective computing databases, the Massachusetts Institute of Technology (MIT) cognitive affective computing database and Germany Augsburg University emotion recognition database were compared, their data structure and data types were compared respectively, and emotional recognition effect based on the data were studied comparatively. The results indicated that the analysis based on the physical parameters could get the effective emotional recognition, and would be a feasible method of pressure emotional evaluation. Because of the lack of stress emotional evaluation data based on the physiological parameters domestically, there is not a public stress emotional database. We hereby built a dataset for the stress evaluation towards the high stress group in colleges, candidates of postgraduates of Ph. D and master as the subjects. We then acquired their physiological parameters, and performed the pressure analysis based on this database. The results indicated that this dataset had a certain reference value for the stress evaluation, and we hope this research can provide a reference and support for emotion evaluation and analysis. PMID:25464787

  3. Databases and coordinated research projects at the IAEA on atomic processes in plasmas

    SciTech Connect

    Braams, Bastiaan J.; Chung, Hyun-Kyung

    2012-05-25

    The Atomic and Molecular Data Unit at the IAEA works with a network of national data centres to encourage and coordinate production and dissemination of fundamental data for atomic, molecular and plasma-material interaction (A+M/PMI) processes that are relevant to the realization of fusion energy. The Unit maintains numerical and bibliographical databases and has started a Wiki-style knowledge base. The Unit also contributes to A+M database interface standards and provides a search engine that offers a common interface to multiple numerical A+M/PMI databases. Coordinated Research Projects (CRPs) bring together fusion energy researchers and atomic, molecular and surface physicists for joint work towards the development of new data and new methods. The databases and current CRPs on A+M/PMI processes are briefly described here.

  4. Real-time magnetic resonance imaging and electromagnetic articulography database for speech production research (TC)

    PubMed Central

    Narayanan, Shrikanth; Toutios, Asterios; Ramanarayanan, Vikram; Lammert, Adam; Kim, Jangwon; Lee, Sungbok; Nayak, Krishna; Kim, Yoon-Chul; Zhu, Yinghua; Goldstein, Louis; Byrd, Dani; Bresch, Erik; Ghosh, Prasanta; Katsamanis, Athanasios; Proctor, Michael

    2014-01-01

    USC-TIMIT is an extensive database of multimodal speech production data, developed to complement existing resources available to the speech research community and with the intention of being continuously refined and augmented. The database currently includes real-time magnetic resonance imaging data from five male and five female speakers of American English. Electromagnetic articulography data have also been presently collected from four of these speakers. The two modalities were recorded in two independent sessions while the subjects produced the same 460 sentence corpus used previously in the MOCHA-TIMIT database. In both cases the audio signal was recorded and synchronized with the articulatory data. The database and companion software are freely available to the research community. PMID:25190403

  5. Real-time magnetic resonance imaging and electromagnetic articulography database for speech production research (TC).

    PubMed

    Narayanan, Shrikanth; Toutios, Asterios; Ramanarayanan, Vikram; Lammert, Adam; Kim, Jangwon; Lee, Sungbok; Nayak, Krishna; Kim, Yoon-Chul; Zhu, Yinghua; Goldstein, Louis; Byrd, Dani; Bresch, Erik; Ghosh, Prasanta; Katsamanis, Athanasios; Proctor, Michael

    2014-09-01

    USC-TIMIT is an extensive database of multimodal speech production data, developed to complement existing resources available to the speech research community and with the intention of being continuously refined and augmented. The database currently includes real-time magnetic resonance imaging data from five male and five female speakers of American English. Electromagnetic articulography data have also been presently collected from four of these speakers. The two modalities were recorded in two independent sessions while the subjects produced the same 460 sentence corpus used previously in the MOCHA-TIMIT database. In both cases the audio signal was recorded and synchronized with the articulatory data. The database and companion software are freely available to the research community. PMID:25190403

  6. Large-scale spatial population databases in infectious disease research

    PubMed Central

    2012-01-01

    Modelling studies on the spatial distribution and spread of infectious diseases are becoming increasingly detailed and sophisticated, with global risk mapping and epidemic modelling studies now popular. Yet, in deriving populations at risk of disease estimates, these spatial models must rely on existing global and regional datasets on population distribution, which are often based on outdated and coarse resolution data. Moreover, a variety of different methods have been used to model population distribution at large spatial scales. In this review we describe the main global gridded population datasets that are freely available for health researchers and compare their construction methods, and highlight the uncertainties inherent in these population datasets. We review their application in past studies on disease risk and dynamics, and discuss how the choice of dataset can affect results. Moreover, we highlight how the lack of contemporary, detailed and reliable data on human population distribution in low income countries is proving a barrier to obtaining accurate large-scale estimates of population at risk and constructing reliable models of disease spread, and suggest research directions required to further reduce these barriers. PMID:22433126

  7. The Pitfalls of Cyberspace and Electronic Database Research--Who Sells What to Whom for Which Audience?

    ERIC Educational Resources Information Center

    Willey, Susan

    2000-01-01

    Raises questions about the validity and reliability of doing research online via the proliferation of academic databases. Finds different versions of the Lexis-Nexis database have differing search capabilities. Argues that dependence on database research findings means dependence on decisions made by a few people who design search engines and…

  8. Data Recycling: Using Existing Databases to Increase Research Capacity in Speech-Language Development and Disorders

    ERIC Educational Resources Information Center

    Justice, Laura M.; Breit-Smith, Allison; Rogers, Margaret

    2010-01-01

    Purpose: This clinical forum was organized to provide a means for informing the research and clinical communities of one mechanism through which research capacity might be enhanced within the field of speech-language pathology. Specifically, forum authors describe the process of conducting secondary analyses of extant databases to answer questions…

  9. A Leslie matrix model for Sicyopterus lagocephalus in La Réunion: sensitivity, uncertainty and research prioritization.

    PubMed

    Artzrouni, Marc; Teichert, Nils; Mara, Thierry

    2014-10-01

    We propose a Leslie matrix model for the population dynamics of Sicyopterus lagocephalus in La Réunion. In order to capture both the amphidromous and the seasonal natures of the species' life history the model has four stages (sea+three river sites) and is cyclical with a 12 month period. Baseline parameters (age-specific fecundity, spatial dispersion patterns and survival rates) were chosen in such a way that the dominant eigenvalue of the year-on-year projection matrix is 1. Large uncertainties on the parameter values preclude the use of the model for management purpose. A sensitivity/uncertainty analysis sheds light on the parameters that cause much of the output to vary and that are poorly known: the life expectancy in rivers and the mortality both at river mouths and during the drift of larvae to sea. The aim is to help policymakers and researchers prioritize data acquisition efforts. The ultimate goal is a sustainable management of Sicyopterus lagocephalus in La Réunion. PMID:25128334

  10. Analytical methods and database design: implications for transplant researchers, 2005.

    PubMed

    Levine, G N; McCullough, K P; Rodgers, A M; Dickinson, D M; Ashby, V B; Schaubel, D E

    2006-01-01

    Understanding how transplant data are collected is crucial to understanding how the data can be used. The collection and use of Organ Procurement and Transplantation Network/Scientific Registry of Transplant Recipients (OPTN/SRTR) data continues to evolve, leading to improvements in data quality, timeliness and scope while reducing the data collection burden. Additional ascertainment of outcomes completes and validates existing data, although caveats remain for researchers. We also consider analytical issues related to cohort choice, timing of data submission, and transplant center variations in follow-up data. All of these points should be carefully considered when choosing cohorts and data sources for analysis. The second part of the article describes some of the statistical methods for outcome analysis employed by the SRTR. Issues of cohort and follow-up period selection lead into a discussion of outcome definitions, event ascertainment, censoring and covariate adjustment. We describe methods for computing unadjusted mortality rates and survival probabilities, and estimating covariate effects through regression modeling. The article concludes with a description of simulated allocation modeling, developed by the SRTR for comparing outcomes of proposed changes to national organ allocation policies. PMID:16613598

  11. Facilitating Research in Physician Assistant Programs: Creating a Student-Level Longitudinal Database.

    PubMed

    Morgan, Perri; Humeniuk, Katherine M; Everett, Christine M

    2015-09-01

    As physician assistant (PA) roles expand and diversify in the United States and around the world, there is a pressing need for research that illuminates how PAs may best be selected, educated, and used in health systems to maximize their potential contributions to health. Physician assistant education programs are well positioned to advance this research by collecting and organizing data on applicants, students, and graduates. Our PA program is creating a permanent longitudinal education database for research that contains extensive student-level data. This database will allow us to conduct research on all phases of PA education, from admission processes through the professional practice of our graduates. In this article, we describe our approach to constructing a longitudinal student-level research database and discuss the strengths and limitations of longitudinal databases for research on education and the practice of PAs. We hope to encourage other PA programs to initiate similar projects so that, in the future, data can be combined for use in multi-institutional research that can contribute to improved education for PA students across programs. PMID:26244470

  12. Nuclear proliferation from the former Soviet Union and the effects of US economic incentives. Research report

    SciTech Connect

    Zimmerman, C.L.

    1996-12-31

    This paper examines the United States` role in stemming nuclear proliferation from the states of the Former Soviet Union. Proliferation from the FSU is a critical danger to the world. Because of the breakdown of many of the security structures within the FSU which formerly ensured the safety of their weapons of mass destruction (WMD) and related material, the danger is very real. The implementation of the START treaties has also generated a great deal of excess fissile material. Because of the economic conditions in the FSU, there is rising crime concerning the sale and distribution of this material. Finally, this paper examines the U.S. role in decreasing the danger of nuclear catastrophe caused by the lack of control. The primary force used in this effort is the Cooperative Threat Reduction Act (CTR) - better know as the Nunn-Lugar Program - which was initiated in 1991 immediately after the failed coup attempt in Moscow. The paper examines in broad scope the types of efforts that CTR supports and gives examples of how that money is being spent. The paper takes the position that the CTR is extremely important to the vital interests of the United States. Recommendations are then given to enhance this vital program.

  13. A RESEARCH DATABASE FOR IMPROVED DATA MANAGEMENT AND ANALYSIS IN LONGITUDINAL STUDIES

    PubMed Central

    BIELEFELD, ROGER A.; YAMASHITA, TOYOKO S.; KEREKES, EDWARD F.; ERCANLI, EHAT; SINGER, LYNN T.

    2014-01-01

    We developed a research database for a five-year prospective investigation of the medical, social, and developmental correlates of chronic lung disease during the first three years of life. We used the Ingres database management system and the Statit statistical software package. The database includes records containing 1300 variables each, the results of 35 psychological tests, each repeated five times (providing longitudinal data on the child, the parents, and behavioral interactions), both raw and calculated variables, and both missing and deferred values. The four-layer menu-driven user interface incorporates automatic activation of complex functions to handle data verification, missing and deferred values, static and dynamic backup, determination of calculated values, display of database status, reports, bulk data extraction, and statistical analysis. PMID:7596250

  14. Patient-related risk factors for fracture-healing complications in the United Kingdom General Practice Research Database

    PubMed Central

    2012-01-01

    Background and purpose A variety of risk factors have been hypothesized to contribute to the development of fracture-healing complications; however, population-based estimates of the strength of these risk factors are limited. In this case-control study, we evaluated patient-related risk factors for fracture-healing complications. Methods Using the United Kingdom General Practice Research Database, we identified patients with a fracture-healing complication (delayed union, nonunion, or malunion) between 1988 and 2008. 4 controls (i.e. patients with normal healing) were matched to each case on general practice, fracture site, fracture date, and length of history in the database. We used conditional logistic regression to estimate odds ratios (ORs) of various risk factors, including demographics, comorbidities, and medication use. Results Diabetes and use of non-steroidal anti-inflammatory drugs (NSAIDs) within 12 months before the initial fracture were associated with a higher odds of a fracture-healing complication (type-I diabetes: adjusted OR = 2.3, 95% CI: 1.3–3.8; type-II diabetes: adjusted OR = 2.3, CI: 1.4–3.7; NSAIDs: adjusted OR = 2.6, CI: 2.1–3.2). Patients who had a motor vehicle accident recorded within 1 month before their initial fracture were also at increased odds of a fracture-healing complication (adjusted OR = 2.6, CI: 1.2–5.4). Interpretation Diabetes, NSAID use, and a recent motor vehicle accident were most consistently associated with an increased risk of a fracture-healing complication, regardless of fracture site or specific fracture-healing complication. This analysis suggests that certain patient-related characteristics influence the development of fracture-healing complications in general, even though specific healing complications may differ by their mechanism. PMID:23140093

  15. Privacy protection and public goods: building a genetic database for health research in Newfoundland and Labrador

    PubMed Central

    Pullman, Daryl; Perrot-Daley, Astrid; Hodgkinson, Kathy; Street, Catherine; Rahman, Proton

    2013-01-01

    Objective To provide a legal and ethical analysis of some of the implementation challenges faced by the Population Therapeutics Research Group (PTRG) at Memorial University (Canada), in using genealogical information offered by individuals for its genetics research database. Materials and methods This paper describes the unique historical and genetic characteristics of the Newfoundland and Labrador founder population, which gave rise to the opportunity for PTRG to build the Newfoundland Genealogy Database containing digitized records of all pre-confederation (1949) census records of the Newfoundland founder population. In addition to building the database, PTRG has developed the Heritability Analytics Infrastructure, a data management structure that stores genotype, phenotype, and pedigree information in a single database, and custom linkage software (KINNECT) to perform pedigree linkages on the genealogy database. Discussion A newly adopted legal regimen in Newfoundland and Labrador is discussed. It incorporates health privacy legislation with a unique research ethics statute governing the composition and activities of research ethics boards and, for the first time in Canada, elevating the status of national research ethics guidelines into law. The discussion looks at this integration of legal and ethical principles which provides a flexible and seamless framework for balancing the privacy rights and welfare interests of individuals, families, and larger societies in the creation and use of research data infrastructures as public goods. Conclusion The complementary legal and ethical frameworks that now coexist in Newfoundland and Labrador provide the legislative authority, ethical legitimacy, and practical flexibility needed to find a workable balance between privacy interests and public goods. Such an approach may also be instructive for other jurisdictions as they seek to construct and use biobanks and related research platforms for genetic research. PMID:22859644

  16. Moving to Google Cloud: Renovation of Global Borehole Temperature Database for Climate Research

    NASA Astrophysics Data System (ADS)

    Xiong, Y.; Huang, S.

    2013-12-01

    Borehole temperature comprises an independent archive of information on climate change which is complementary to the instrumental and other proxy climate records. With support from the international geothermal community, a global database of borehole temperatures has been constructed for the specific purpose of the study on climate change. Although this database has become an important data source in climate research, there are certain limitations partially because the framework of the existing borehole temperature database was hand-coded some twenty years ago. A database renovation work is now underway to take the advantages of the contemporary online database technologies. The major intended improvements include 1) dynamically linking a borehole site to Google Earth to allow for inspection of site specific geographical information; 2) dynamically linking an original key reference of a given borehole site to Google Scholar to allow for a complete list of related publications; and 3) enabling site selection and data download based on country, coordinate range, and contributor. There appears to be a good match between the enhancement requirements for this database and the functionalities of the newly released Google Fusion Tables application. Google Fusion Tables is a cloud-based service for data management, integration, and visualization. This experimental application can consolidate related online resources such as Google Earth, Google Scholar, and Google Drive for sharing and enriching an online database. It is user friendly, allowing users to apply filters and to further explore the internet for additional information regarding the selected data. The users also have ways to map, to chart, and to calculate on the selected data, and to download just the subset needed. The figure below is a snapshot of the database currently under Google Fusion Tables renovation. We invite contribution and feedback from the geothermal and climate research community to make the global database of borehole temperatures an even better resource in climate research. Acknowledgement: This work is supported by NSF Grant 1202673. Google Fusion Tables Interface of the Global Database of Borehole Temperatures and Climate Reconstructions

  17. Development of a pseudo/anonymised primary care research database: Proof-of-concept study.

    PubMed

    MacRury, Sandra; Finlayson, Jim; Hussey-Wilson, Susan; Holden, Samantha

    2014-06-15

    General practice records present a comprehensive source of data that could form a variety of anonymised or pseudonymised research databases to aid identification of potential research participants regardless of location. A proof-of-concept study was undertaken to extract data from general practice systems in 15 practices across the region to form pseudo and anonymised research data sets. Two feasibility studies and a disease surveillance study compared numbers of potential study participants and accuracy of disease prevalence, respectively. There was a marked reduction in screening time and increase in numbers of potential study participants identified with the research repository compared with conventional methods. Accurate disease prevalence was established and enhanced with the addition of selective text mining. This study confirms the potential for development of national anonymised research database from general practice records in addition to improving data collection for local or national audits and epidemiological projects. PMID:24935212

  18. Better safe than sorry: ethics review in European Union-funded health research.

    PubMed

    Draghia-Akli, Ruxandra; Hoeveler, Arnd; Löffler, Peter; Namorado, Joana

    2014-12-01

    Public scrutiny and the increasing number of projects addressing later stages of the research and innovation process announced the need for an enhanced attention to be paid to identify and address ethics concerns. Ex-ante ethics review as implemented in EU-funded health research and a proactive ethics management are a genuinely useful exercise and ensures top-quality research, from the lab to the patient. PMID:25457962

  19. Research exemption/experimental use in the European Union: patents do not block the progress of science.

    PubMed

    Jaenichen, Hans-Rainer; Pitz, Johann

    2015-02-01

    In the public debate about patents, specifically in the area of biotechnology, the position has been taken that patents block the progress of science. As we demonstrate in this review, this is not the case in the European Union (EU). The national patent acts of the EU member states define research and experimental use exemptions from patent infringement that allow sufficient room for research activities to promote innovation. This review provides a comparative overview of the legal requirements and the extent and limitations of experimental use exemptions, including the so-called Bolar provision, in Germany, the United Kingdom, France, Spain, Italy, and The Netherlands. The legal framework in the respective countries is illustrated with reference to practical examples concerning tests on patent-protected genetic targets and antibodies. Specific questions concerning the use of patent-protected research tools, the outsourcing of research activities, and the use of preparatory and supplying acts for experimental purposes that are necessary for conducting experiments are covered. PMID:25377145

  20. Towards the "Fifth Freedom": Increasing the Mobility of Researchers in the European Union

    ERIC Educational Resources Information Center

    Marimon, Ramon; Lietaert, Matthieu; Grigolo, Michele

    2009-01-01

    Many researchers trained in Europe leave to work abroad, namely in the USA. This brain-drain phenomenon is the result of a lack of openness and competition in European academic systems. Some aspects relating to the mobility of academic careers could make a difference in attracting--and maintaining--researchers, aside to serious structural reform.…

  1. Towards the "Fifth Freedom": Increasing the Mobility of Researchers in the European Union

    ERIC Educational Resources Information Center

    Marimon, Ramon; Lietaert, Matthieu; Grigolo, Michele

    2009-01-01

    Many researchers trained in Europe leave to work abroad, namely in the USA. This brain-drain phenomenon is the result of a lack of openness and competition in European academic systems. Some aspects relating to the mobility of academic careers could make a difference in attracting--and maintaining--researchers, aside to serious structural reform.…

  2. Research on cholinesterases in the Soviet Union and Russia: a historical perspective.

    PubMed

    Rozengart, Eugene V; Basova, Natalia E; Moralev, Serge N; Lushchekina, Sofya V; Masson, Patrick; Varfolomeev, Sergei D

    2013-03-25

    Research on cholinesterases and effects of their inhibition in the USSR and Russia since 1930-1940s till present is exposed in historical aspects. The first physiological and toxicological effects of cholinesterase inhibition were reported by Alexander Ginetsinsky during World War II, when academic institutions were evacuated from Leningrad to Kazan. The main scientific schools that initiated research on chemistry, enzymology and physiology of cholinesterases and their inhibitors were leaded by Alexandr and Boris Arbuzovs, Victor Rozengart, Viktor Yakovlev, Michael Michelson, Martin Kabachnik, Mikhail Voronkov, Ivan Knunyants, Alexandr Bretskin and others. They investigated the main physiological effects of cholinesterase inhibitors, and analyzed the catalytic mechanisms of cholinesterases and related enzymes. Their contributions are landmarks in the history of cholinesterase research. At the present time revival of research on cholinesterases in different universities and institutes is vivid, in particular at the Moscow State University, research institutes of Russian Academy of Sciences and Kazan Scientific Center. PMID:23485591

  3. Union Agitators

    ERIC Educational Resources Information Center

    Honawar, Vaishali

    2006-01-01

    A decade has passed since a few union leaders formed the network known as Teacher Union Reform Network (TURN) to search for innovative ways to enhance education. Selling their message has not always been easy. Created in 1995, TURN was the brain child of Adam Urbanski, the president of the Rochester (N.Y.) Teachers Association for the past 25…

  4. YPED: An Integrated Bioinformatics Suite and Database for Mass Spectrometry-based Proteomics Research

    PubMed Central

    Colangelo, Christopher M.; Shifman, Mark; Cheung, Kei-Hoi; Stone, Kathryn L.; Carriero, Nicholas J.; Gulcicek, Erol E.; Lam, TuKiet T.; Wu, Terence; Bjornson, Robert D.; Bruce, Can; Nairn, Angus C.; Rinehart, Jesse; Miller, Perry L.; Williams, Kenneth R.

    2015-01-01

    We report a significantly-enhanced bioinformatics suite and database for proteomics research called Yale Protein Expression Database (YPED) that is used by investigators at more than 300 institutions worldwide. YPED meets the data management, archival, and analysis needs of a high-throughput mass spectrometry-based proteomics research ranging from a single laboratory, group of laboratories within and beyond an institution, to the entire proteomics community. The current version is a significant improvement over the first version in that it contains new modules for liquid chromatography–tandem mass spectrometry (LC–MS/MS) database search results, label and label-free quantitative proteomic analysis, and several scoring outputs for phosphopeptide site localization. In addition, we have added both peptide and protein comparative analysis tools to enable pairwise analysis of distinct peptides/proteins in each sample and of overlapping peptides/proteins between all samples in multiple datasets. We have also implemented a targeted proteomics module for automated multiple reaction monitoring (MRM)/selective reaction monitoring (SRM) assay development. We have linked YPED’s database search results and both label-based and label-free fold-change analysis to the Skyline Panorama repository for online spectra visualization. In addition, we have built enhanced functionality to curate peptide identifications into an MS/MS peptide spectral library for all of our protein database search identification results. PMID:25712262

  5. AN OVERVIEW OF COMPUTATIONAL LIFE SCIENCE DATABASES & EXCHANGE FORMATS OF RELEVANCE TO CHEMICAL BIOLOGY RESEARCH

    PubMed Central

    Hall, Aaron Smalter; Shan, Yunfeng; Lushington, Gerald; Visvanathan, Mahesh

    2016-01-01

    Databases and exchange formats describing biological entities such as chemicals and proteins, along with their relationships, are a critical component of research in life sciences disciplines, including chemical biology wherein small information about small molecule properties converges with cellular and molecular biology. Databases for storing biological entities are growing not only in size, but also in type, with many similarities between them and often subtle differences. The data formats available to describe and exchange these entities are numerous as well. In general, each format is optimized for a particular purpose or database, and hence some understanding of these formats is required when choosing one for research purposes. This paper reviews a selection of different databases and data formats with the goal of summarizing their purposes, features, and limitations. Databases are reviewed under the categories of 1) protein interactions, 2) metabolic pathways, 3) chemical interactions, and 4) drug discovery. Representation formats will be discussed according to those describing chemical structures, and those describing genomic/proteomic entities. PMID:22934944

  6. Building Infectious Disease Research Programs to Promote Security and Enhance Collaborations with Countries of the Former Soviet Union.

    PubMed

    Bartholomew, James C; Pearson, Andrew D; Stenseth, Nils Chr; LeDuc, James W; Hirschberg, David L; Colwell, Rita R

    2015-01-01

    Addressing the threat of infectious diseases, whether natural, the results of a laboratory accident, or a deliberate act of bioterrorism, requires no corner of the world be ignored. The mobility of infectious agents and their rapid adaptability, whether to climate change or socioeconomic drivers or both, demand the science employed to understand these processes be advanced and tailored to a country or a region, but with a global vision. In many parts of the world, largely because of economic struggles, scientific capacity has not kept pace with the need to accomplish this goal and has left these regions and hence the world vulnerable to infectious disease outbreaks. To build scientific capability in a developing region requires cooperation and participation of experienced international scientists who understand the issues and are committed to educate the next generations of young investigators in the region. These efforts need to be coupled with the understanding and resolve of local governments and international agencies to promote an aggressive science agenda. International collaborative scientific investigation of infectious diseases not only adds significantly to scientific knowledge, but it promotes health security, international trust, and long-term economic benefit to the region involved. This premise is based on the observation that the most powerful human inspiration is that which brings peoples together to work on and solve important global challenges. The republics of the former Soviet Union provide a valuable case study for the need to rebuild scientific capacity as they are located at the crossroads where many of the world's great epidemics began. The scientific infrastructure and disease surveillance capabilities of the region suffered significant decline after the breakup of the Soviet Union. The U.S. Cooperative Threat Reduction (CTR) Program, a part of the U.S. Department of Defense, together with partner countries, have worked diligently to improve the capabilities in this region to guard against the potential future risk from especially dangerous pathogens. The dissolution of the Soviet Union left behind many scientists still working to study pathogens using antiquated protocols in unsafe laboratories. To address this situation, the CTR program began improving laboratory infrastructure, establishing biosafety and biosecurity programs, and training scientists in modern techniques, with emphasis on biosurveillance and safe containment of especially dangerous pathogens. In the Republic of Georgia, this effort culminated in the construction of a modern containment laboratory, the Richard G. Lugar Center for Public Health Research in Tbilisi to house both isolated especially dangerous pathogens as well as the research to be conducted on these agents. The need now is to utilize and sustain the investment made by CTR by establishing strong public and animal health science programs in these facilities tailored to the needs of the region and the goals for which this investment was made. A similar effort is ongoing in other former Soviet Republics. Here, we provide the analysis and recommendations of an international panel of expert scientists appointed by the Cooperative Biological Engagement Program of the Defense Threat Reduction Agency to provide advice to the stakeholders on the scientific path for the future. The emphasis is on an implementation strategy for decision makers and scientists to consider providing a sustainable biological science program in support of the One Health initiative. Opportunities, potential barriers, and lessons learned while meeting the needs of the Republic of Georgia and the Caucasus region are discussed. It is hoped that this effort will serve as a model for similar scientific needs in not only the former Soviet Union republics but also other regions challenged by infectious diseases where the CTR program operates. PMID:26636067

  7. Building Infectious Disease Research Programs to Promote Security and Enhance Collaborations with Countries of the Former Soviet Union

    PubMed Central

    Bartholomew, James C.; Pearson, Andrew D.; Stenseth, Nils Chr.; LeDuc, James W.; Hirschberg, David L.; Colwell, Rita R.

    2015-01-01

    Addressing the threat of infectious diseases, whether natural, the results of a laboratory accident, or a deliberate act of bioterrorism, requires no corner of the world be ignored. The mobility of infectious agents and their rapid adaptability, whether to climate change or socioeconomic drivers or both, demand the science employed to understand these processes be advanced and tailored to a country or a region, but with a global vision. In many parts of the world, largely because of economic struggles, scientific capacity has not kept pace with the need to accomplish this goal and has left these regions and hence the world vulnerable to infectious disease outbreaks. To build scientific capability in a developing region requires cooperation and participation of experienced international scientists who understand the issues and are committed to educate the next generations of young investigators in the region. These efforts need to be coupled with the understanding and resolve of local governments and international agencies to promote an aggressive science agenda. International collaborative scientific investigation of infectious diseases not only adds significantly to scientific knowledge, but it promotes health security, international trust, and long-term economic benefit to the region involved. This premise is based on the observation that the most powerful human inspiration is that which brings peoples together to work on and solve important global challenges. The republics of the former Soviet Union provide a valuable case study for the need to rebuild scientific capacity as they are located at the crossroads where many of the world’s great epidemics began. The scientific infrastructure and disease surveillance capabilities of the region suffered significant decline after the breakup of the Soviet Union. The U.S. Cooperative Threat Reduction (CTR) Program, a part of the U.S. Department of Defense, together with partner countries, have worked diligently to improve the capabilities in this region to guard against the potential future risk from especially dangerous pathogens. The dissolution of the Soviet Union left behind many scientists still working to study pathogens using antiquated protocols in unsafe laboratories. To address this situation, the CTR program began improving laboratory infrastructure, establishing biosafety and biosecurity programs, and training scientists in modern techniques, with emphasis on biosurveillance and safe containment of especially dangerous pathogens. In the Republic of Georgia, this effort culminated in the construction of a modern containment laboratory, the Richard G. Lugar Center for Public Health Research in Tbilisi to house both isolated especially dangerous pathogens as well as the research to be conducted on these agents. The need now is to utilize and sustain the investment made by CTR by establishing strong public and animal health science programs in these facilities tailored to the needs of the region and the goals for which this investment was made. A similar effort is ongoing in other former Soviet Republics. Here, we provide the analysis and recommendations of an international panel of expert scientists appointed by the Cooperative Biological Engagement Program of the Defense Threat Reduction Agency to provide advice to the stakeholders on the scientific path for the future. The emphasis is on an implementation strategy for decision makers and scientists to consider providing a sustainable biological science program in support of the One Health initiative. Opportunities, potential barriers, and lessons learned while meeting the needs of the Republic of Georgia and the Caucasus region are discussed. It is hoped that this effort will serve as a model for similar scientific needs in not only the former Soviet Union republics but also other regions challenged by infectious diseases where the CTR program operates. PMID:26636067

  8. Analysis of Institutionally Specific Retention Research: A Comparison between Survey and Institutional Database Methods

    ERIC Educational Resources Information Center

    Caison, Amy L.

    2007-01-01

    This study empirically explores the comparability of traditional survey-based retention research methodology with an alternative approach that relies on data commonly available in institutional student databases. Drawing on Tinto's [Tinto, V. (1993). "Leaving College: Rethinking the Causes and Cures of Student Attrition" (2nd Ed.), The University…

  9. Heavy Oil Database from the National Institute for Petroleum and Energy Research (NIPER)

    DOE Data Explorer

    The Heavy Oil Database resulted from work funded by DOE and performed at the National Institute for Petroleum and Energy Research (NIPER). It contains information on more than 500 resevoirs in a Microsoft Excel spreadsheet. The information was collected in 1992 and updated periodically through 2003. Save the zipped file to your PC, then open to access the data.

  10. Interacting with the National Database for Autism Research (NDAR) via the LONI Pipeline workflow environment.

    PubMed

    Torgerson, Carinna M; Quinn, Catherine; Dinov, Ivo; Liu, Zhizhong; Petrosyan, Petros; Pelphrey, Kevin; Haselgrove, Christian; Kennedy, David N; Toga, Arthur W; Van Horn, John Darrell

    2015-03-01

    Under the umbrella of the National Database for Clinical Trials (NDCT) related to mental illnesses, the National Database for Autism Research (NDAR) seeks to gather, curate, and make openly available neuroimaging data from NIH-funded studies of autism spectrum disorder (ASD). NDAR has recently made its database accessible through the LONI Pipeline workflow design and execution environment to enable large-scale analyses of cortical architecture and function via local, cluster, or "cloud"-based computing resources. This presents a unique opportunity to overcome many of the customary limitations to fostering biomedical neuroimaging as a science of discovery. Providing open access to primary neuroimaging data, workflow methods, and high-performance computing will increase uniformity in data collection protocols, encourage greater reliability of published data, results replication, and broaden the range of researchers now able to perform larger studies than ever before. To illustrate the use of NDAR and LONI Pipeline for performing several commonly performed neuroimaging processing steps and analyses, this paper presents example workflows useful for ASD neuroimaging researchers seeking to begin using this valuable combination of online data and computational resources. We discuss the utility of such database and workflow processing interactivity as a motivation for the sharing of additional primary data in ASD research and elsewhere. PMID:25666423

  11. Analysis of Institutionally Specific Retention Research: A Comparison between Survey and Institutional Database Methods

    ERIC Educational Resources Information Center

    Caison, Amy L.

    2007-01-01

    This study empirically explores the comparability of traditional survey-based retention research methodology with an alternative approach that relies on data commonly available in institutional student databases. Drawing on Tinto's [Tinto, V. (1993). "Leaving College: Rethinking the Causes and Cures of Student Attrition" (2nd Ed.), The University…

  12. Current Trends and New Challenges of Databases and Web Applications for Systems Driven Biological Research

    PubMed Central

    Sreenivasaiah, Pradeep Kumar; Kim, Do Han

    2010-01-01

    Dynamic and rapidly evolving nature of systems driven research imposes special requirements on the technology, approach, design and architecture of computational infrastructure including database and Web application. Several solutions have been proposed to meet the expectations and novel methods have been developed to address the persisting problems of data integration. It is important for researchers to understand different technologies and approaches. Having familiarized with the pros and cons of the existing technologies, researchers can exploit its capabilities to the maximum potential for integrating data. In this review we discuss the architecture, design and key technologies underlying some of the prominent databases and Web applications. We will mention their roles in integration of biological data and investigate some of the emerging design concepts and computational technologies that are likely to have a key role in the future of systems driven biomedical research. PMID:21423387

  13. Immediate Dissemination of Student Discoveries to a Model Organism Database Enhances Classroom-Based Research Experiences

    PubMed Central

    Wiley, Emily A.; Stover, Nicholas A.

    2014-01-01

    Use of inquiry-based research modules in the classroom has soared over recent years, largely in response to national calls for teaching that provides experience with scientific processes and methodologies. To increase the visibility of in-class studies among interested researchers and to strengthen their impact on student learning, we have extended the typical model of inquiry-based labs to include a means for targeted dissemination of student-generated discoveries. This initiative required: 1) creating a set of research-based lab activities with the potential to yield results that a particular scientific community would find useful and 2) developing a means for immediate sharing of student-generated results. Working toward these goals, we designed guides for course-based research aimed to fulfill the need for functional annotation of the Tetrahymena thermophila genome, and developed an interactive Web database that links directly to the official Tetrahymena Genome Database for immediate, targeted dissemination of student discoveries. This combination of research via the course modules and the opportunity for students to immediately “publish” their novel results on a Web database actively used by outside scientists culminated in a motivational tool that enhanced students’ efforts to engage the scientific process and pursue additional research opportunities beyond the course. PMID:24591511

  14. Psychology and Education of the Learning Disabled Child in the Soviet Union. Research Report No. 78.

    ERIC Educational Resources Information Center

    Wozniak, R. H.

    The author surveys the status in the USSR of educational programing and psychological research with learning disabled children who are classified as temporarily retarded in psychological development (TRPD). Education and psychology in the USSR are said to be marked by the following major characteristics: a strong emphasis on the importance of…

  15. Scientific Research with the Space Telescope: International Astronomical Union Colloquium No. 54. [conferences

    NASA Technical Reports Server (NTRS)

    Longair, M. S.; Warner, J. W.

    1979-01-01

    The application of the space telescope for extragalactic astronomy, planetary research, and stellar, interstellar, and galactic structural problems is discussed. Topics include investigations of small solar system objects, the physical characteristics of ionized gaseous nebulae, the central regions of active galaxies and quasars, problems of cosmology, and the distribution and composition of interstellar matter.

  16. The Evolving Role of Union Learning Representatives

    ERIC Educational Resources Information Center

    Moore, Sian; Ross, Cilla

    2008-01-01

    This article suggests that the union learning representative (ULR) is increasingly situated at the heart of trade union activity. The paper draws upon recent research based on interviews with national trade union officers and case studies of union learning activity to explore the competing demands being made upon ULRs and the implications for…

  17. DriverDBv2: a database for human cancer driver gene research

    PubMed Central

    Chung, I-Fang; Chen, Chen-Yang; Su, Shih-Chieh; Li, Chia-Yang; Wu, Kou-Juey; Wang, Hsei-Wei; Cheng, Wei-Chung

    2016-01-01

    We previously presented DriverDB, a database that incorporates ∼6000 cases of exome-seq data, in addition to annotation databases and published bioinformatics algorithms dedicated to driver gene/mutation identification. The database provides two points of view, ‘Cancer’ and ‘Gene’, to help researchers visualize the relationships between cancers and driver genes/mutations. In the updated DriverDBv2 database (http://ngs.ym.edu.tw/driverdb) presented herein, we incorporated >9500 cancer-related RNA-seq datasets and >7000 more exome-seq datasets from The Cancer Genome Atlas (TCGA), International Cancer Genome Consortium (ICGC), and published papers. Seven additional computational algorithms (meaning that the updated database contains 15 in total), which were developed for driver gene identification, are incorporated into our analysis pipeline, and the results are provided in the ‘Cancer’ section. Furthermore, there are two main new features, ‘Expression’ and ‘Hotspot’, in the ‘Gene’ section. ‘Expression’ displays two expression profiles of a gene in terms of sample types and mutation types, respectively. ‘Hotspot’ indicates the hotspot mutation regions of a gene according to the results provided by four bioinformatics tools. A new function, ‘Gene Set’, allows users to investigate the relationships among mutations, expression levels and clinical data for a set of genes, a specific dataset and clinical features. PMID:26635391

  18. DriverDBv2: a database for human cancer driver gene research.

    PubMed

    Chung, I-Fang; Chen, Chen-Yang; Su, Shih-Chieh; Li, Chia-Yang; Wu, Kou-Juey; Wang, Hsei-Wei; Cheng, Wei-Chung

    2016-01-01

    We previously presented DriverDB, a database that incorporates ?6000 cases of exome-seq data, in addition to annotation databases and published bioinformatics algorithms dedicated to driver gene/mutation identification. The database provides two points of view, 'Cancer' and 'Gene', to help researchers visualize the relationships between cancers and driver genes/mutations. In the updated DriverDBv2 database (http://ngs.ym.edu.tw/driverdb) presented herein, we incorporated >9500 cancer-related RNA-seq datasets and >7000 more exome-seq datasets from The Cancer Genome Atlas (TCGA), International Cancer Genome Consortium (ICGC), and published papers. Seven additional computational algorithms (meaning that the updated database contains 15 in total), which were developed for driver gene identification, are incorporated into our analysis pipeline, and the results are provided in the 'Cancer' section. Furthermore, there are two main new features, 'Expression' and 'Hotspot', in the 'Gene' section. 'Expression' displays two expression profiles of a gene in terms of sample types and mutation types, respectively. 'Hotspot' indicates the hotspot mutation regions of a gene according to the results provided by four bioinformatics tools. A new function, 'Gene Set', allows users to investigate the relationships among mutations, expression levels and clinical data for a set of genes, a specific dataset and clinical features. PMID:26635391

  19. Web-based database for the management of tissue specimens in a transregional histological research facility

    PubMed Central

    2011-01-01

    Background In the setting of a histological research core facility sample tracking and project specific archiving of tissue specimens and communication of related data is of central importance. Description Over a 24-month period 10 laboratories from two transregional research centers submitted in excess of 3000 tissue samples for histological processing and evaluation to our core facility. A web based database was set up to overcome the logistical problem of managing samples with inconsistent, duplicate and missing labels and to allow for efficient sample tracking, archiving and communication with the collaborating research laboratories. The database allows the users to remotely generate unique sample identifiers and enter sample annotation prior to sample processing. Furthermore the database facilitates communication about experimental set-up results and media files such as histological images. Conclusion Our newly constructed web based portal is an important tool for the management of research samples of our histological core facility and facilitates significantly interdisciplinary and transregional research. It is freely available for scientific use. PMID:21392381

  20. Sys-BodyFluid: a systematical database for human body fluid proteome research.

    PubMed

    Li, Su-Jun; Peng, Mao; Li, Hong; Liu, Bo-Shu; Wang, Chuan; Wu, Jia-Rui; Li, Yi-Xue; Zeng, Rong

    2009-01-01

    Recently, body fluids have widely become an important target for proteomic research and proteomic study has produced more and more body fluid related protein data. A database is needed to collect and analyze these proteome data. Thus, we developed this web-based body fluid proteome database Sys-BodyFluid. It contains eleven kinds of body fluid proteomes, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar lavage fluid, synovial fluid, nipple aspirate fluid, tear fluid, seminal fluid, human milk and amniotic fluid. Over 10,000 proteins are presented in the Sys-BodyFluid. Sys-BodyFluid provides the detailed protein annotations, including protein description, Gene Ontology, domain information, protein sequence and involved pathways. These proteome data can be retrieved by using protein name, protein accession number and sequence similarity. In addition, users can query between these different body fluids to get the different proteins identification information. Sys-BodyFluid database can facilitate the body fluid proteomics and disease proteomics research as a reference database. It is available at http://www.biosino.org/bodyfluid/. PMID:18978022

  1. MIPS PlantsDB: a database framework for comparative plant genome research.

    PubMed

    Nussbaumer, Thomas; Martis, Mihaela M; Roessner, Stephan K; Pfeifer, Matthias; Bader, Kai C; Sharma, Sapna; Gundlach, Heidrun; Spannagl, Manuel

    2013-01-01

    The rapidly increasing amount of plant genome (sequence) data enables powerful comparative analyses and integrative approaches and also requires structured and comprehensive information resources. Databases are needed for both model and crop plant organisms and both intuitive search/browse views and comparative genomics tools should communicate the data to researchers and help them interpret it. MIPS PlantsDB (http://mips.helmholtz-muenchen.de/plant/genomes.jsp) was initially described in NAR in 2007 [Spannagl,M., Noubibou,O., Haase,D., Yang,L., Gundlach,H., Hindemitt, T., Klee,K., Haberer,G., Schoof,H. and Mayer,K.F. (2007) MIPSPlantsDB-plant database resource for integrative and comparative plant genome research. Nucleic Acids Res., 35, D834-D840] and was set up from the start to provide data and information resources for individual plant species as well as a framework for integrative and comparative plant genome research. PlantsDB comprises database instances for tomato, Medicago, Arabidopsis, Brachypodium, Sorghum, maize, rice, barley and wheat. Building up on that, state-of-the-art comparative genomics tools such as CrowsNest are integrated to visualize and investigate syntenic relationships between monocot genomes. Results from novel genome analysis strategies targeting the complex and repetitive genomes of triticeae species (wheat and barley) are provided and cross-linked with model species. The MIPS Repeat Element Database (mips-REdat) and Catalog (mips-REcat) as well as tight connections to other databases, e.g. via web services, are further important components of PlantsDB. PMID:23203886

  2. Second Research Coordination Meeting on Reference Database for Neutron Activation Analysis -- Summary Report

    SciTech Connect

    Firestone, Richard B.; Kellett, Mark A.

    2008-03-19

    The second meeting of the Co-ordinated Research Project on"Reference Database for Neutron Activation Analysis" was held at the IAEA, Vienna from 7-9 May, 2007. A summary of the presentations made by participants is given, along with reports on specifically assigned tasks and subsequent discussions. In order to meet the overall objectives of this CRP, the outputs have been reiterated and new task assignments made.

  3. Genomics and Public Health Research: Can the State Allow Access to Genomic Databases?

    PubMed Central

    Cousineau, J; Girard, N; Monardes, C; Leroux, T; Jean, M Stanton

    2012-01-01

    Because many diseases are multifactorial disorders, the scientific progress in genomics and genetics should be taken into consideration in public health research. In this context, genomic databases will constitute an important source of information. Consequently, it is important to identify and characterize the State’s role and authority on matters related to public health, in order to verify whether it has access to such databases while engaging in public health genomic research. We first consider the evolution of the concept of public health, as well as its core functions, using a comparative approach (e.g. WHO, PAHO, CDC and the Canadian province of Quebec). Following an analysis of relevant Quebec legislation, the precautionary principle is examined as a possible avenue to justify State access to and use of genomic databases for research purposes. Finally, we consider the Influenza pandemic plans developed by WHO, Canada, and Quebec, as examples of key tools framing public health decision-making process. We observed that State powers in public health, are not, in Quebec, well adapted to the expansion of genomics research. We propose that the scope of the concept of research in public health should be clear and include the following characteristics: a commitment to the health and well-being of the population and to their determinants; the inclusion of both applied research and basic research; and, an appropriate model of governance (authorization, follow-up, consent, etc.). We also suggest that the strategic approach version of the precautionary principle could guide collective choices in these matters. PMID:23113174

  4. A European Flood Database: facilitating comprehensive flood research beyond administrative boundaries

    NASA Astrophysics Data System (ADS)

    Hall, J.; Arheimer, B.; Aronica, G. T.; Bilibashi, A.; Boháč, M.; Bonacci, O.; Borga, M.; Burlando, P.; Castellarin, A.; Chirico, G. B.; Claps, P.; Fiala, K.; Gaál, L.; Gorbachova, L.; Gül, A.; Hannaford, J.; Kiss, A.; Kjeldsen, T.; Kohnová, S.; Koskela, J. J.; Macdonald, N.; Mavrova-Guirguinova, M.; Ledvinka, O.; Mediero, L.; Merz, B.; Merz, R.; Molnar, P.; Montanari, A.; Osuch, M.; Parajka, J.; Perdigão, R. A. P.; Radevski, I.; Renard, B.; Rogger, M.; Salinas, J. L.; Sauquet, E.; Šraj, M.; Szolgay, J.; Viglione, A.; Volpi, E.; Wilson, D.; Zaimi, K.; Blöschl, G.

    2015-06-01

    The current work addresses one of the key building blocks towards an improved understanding of flood processes and associated changes in flood characteristics and regimes in Europe: the development of a comprehensive, extensive European flood database. The presented work results from ongoing cross-border research collaborations initiated with data collection and joint interpretation in mind. A detailed account of the current state, characteristics and spatial and temporal coverage of the European Flood Database, is presented. At this stage, the hydrological data collection is still growing and consists at this time of annual maximum and daily mean discharge series, from over 7000 hydrometric stations of various data series lengths. Moreover, the database currently comprises data from over 50 different data sources. The time series have been obtained from different national and regional data sources in a collaborative effort of a joint European flood research agreement based on the exchange of data, models and expertise, and from existing international data collections and open source websites. These ongoing efforts are contributing to advancing the understanding of regional flood processes beyond individual country boundaries and to a more coherent flood research in Europe.

  5. CmMDb: A Versatile Database for Cucumis melo Microsatellite Markers and Other Horticulture Crop Research

    PubMed Central

    Bhawna; Chaduvula, Pavan K.; Bonthala, Venkata S.; Manjusha, Verma; Siddiq, Ebrahimali A.; Polumetla, Ananda K.; Prasad, Gajula M. N. V.

    2015-01-01

    Cucumis melo L. that belongs to Cucurbitaceae family ranks among one of the highest valued horticulture crops being cultivated across the globe. Besides its economical and medicinal importance, Cucumis melo L. is a valuable resource and model system for the evolutionary studies of cucurbit family. However, very limited numbers of molecular markers were reported for Cucumis melo L. so far that limits the pace of functional genomic research in melon and other similar horticulture crops. We developed the first whole genome based microsatellite DNA marker database of Cucumis melo L. and comprehensive web resource that aids in variety identification and physical mapping of Cucurbitaceae family. The Cucumis melo L. microsatellite database (CmMDb: http://65.181.125.102/cmmdb2/index.html) encompasses 39,072 SSR markers along with its motif repeat, motif length, motif sequence, marker ID, motif type and chromosomal locations. The database is featured with novel automated primer designing facility to meet the needs of wet lab researchers. CmMDb is a freely available web resource that facilitates the researchers to select the most appropriate markers for marker-assisted selection in melons and to improve breeding strategies. PMID:25885062

  6. A DICOM based radiotherapy plan database for research collaboration and reporting

    NASA Astrophysics Data System (ADS)

    Westberg, J.; Krogh, S.; Brink, C.; Vogelius, I. R.

    2014-03-01

    Purpose: To create a central radiotherapy (RT) plan database for dose analysis and reporting, capable of calculating and presenting statistics on user defined patient groups. The goal is to facilitate multi-center research studies with easy and secure access to RT plans and statistics on protocol compliance. Methods: RT institutions are able to send data to the central database using DICOM communications on a secure computer network. The central system is composed of a number of DICOM servers, an SQL database and in-house developed software services to process the incoming data. A web site within the secure network allows the user to manage their submitted data. Results: The RT plan database has been developed in Microsoft .NET and users are able to send DICOM data between RT centers in Denmark. Dose-volume histogram (DVH) calculations performed by the system are comparable to those of conventional RT software. A permission system was implemented to ensure access control and easy, yet secure, data sharing across centers. The reports contain DVH statistics for structures in user defined patient groups. The system currently contains over 2200 patients in 14 collaborations. Conclusions: A central RT plan repository for use in multi-center trials and quality assurance was created. The system provides an attractive alternative to dummy runs by enabling continuous monitoring of protocol conformity and plan metrics in a trial.

  7. Kal-Haiti a Research Database for Risks Management and Sustainable Reconstruction in Haiti

    NASA Astrophysics Data System (ADS)

    Giros, A.; Fontannaz, D.; Allenbach, B.; Treinsoutrot, D.; De Michele, M.

    2012-07-01

    Following the 12th January 2010 earthquake in Haiti, the French Agence Nationale de la Recherche has funded a project named KAL-Haiti which aims at gathering remote sensing imagery as well as in-situ and exogenous data into a knowledge base. This database, seen as a shareable resource, can serve as a basis for helping the reconstruction of the country, but also as a reference for scientific studies devoted to all phases of risk management. The project main outcome will be a geo-referenced database containing a selection of remotely sensed imagery acquired before and after the disastrous event supplemented with all relevant ancillary data, and enriched with in-situ measurements and exogenous data. The resulting reference database is freely available for research and for reconstruction tasks. It is strongly expected that users will also become contributors by sharing their own data production, thus participating to the growth of the initial kernel. The database will also be enriched with new satellite images, monitoring the evolution of the Haitian situation over the next 10 years.

  8. MIMIC II: a massive temporal ICU patient database to support research in intelligent patient monitoring

    NASA Technical Reports Server (NTRS)

    Saeed, M.; Lieu, C.; Raber, G.; Mark, R. G.

    2002-01-01

    Development and evaluation of Intensive Care Unit (ICU) decision-support systems would be greatly facilitated by the availability of a large-scale ICU patient database. Following our previous efforts with the MIMIC (Multi-parameter Intelligent Monitoring for Intensive Care) Database, we have leveraged advances in networking and storage technologies to develop a far more massive temporal database, MIMIC II. MIMIC II is an ongoing effort: data is continuously and prospectively archived from all ICU patients in our hospital. MIMIC II now consists of over 800 ICU patient records including over 120 gigabytes of data and is growing. A customized archiving system was used to store continuously up to four waveforms and 30 different parameters from ICU patient monitors. An integrated user-friendly relational database was developed for browsing of patients' clinical information (lab results, fluid balance, medications, nurses' progress notes). Based upon its unprecedented size and scope, MIMIC II will prove to be an important resource for intelligent patient monitoring research, and will support efforts in medical data mining and knowledge-discovery.

  9. APD3: the antimicrobial peptide database as a tool for research and education.

    PubMed

    Wang, Guangshun; Li, Xia; Wang, Zhe

    2016-01-01

    The antimicrobial peptide database (APD, http://aps.unmc.edu/AP/) is an original database initially online in 2003. The APD2 (2009 version) has been regularly updated and further expanded into the APD3. This database currently focuses on natural antimicrobial peptides (AMPs) with defined sequence and activity. It includes a total of 2619 AMPs with 261 bacteriocins from bacteria, 4 AMPs from archaea, 7 from protists, 13 from fungi, 321 from plants and 1972 animal host defense peptides. The APD3 contains 2169 antibacterial, 172 antiviral, 105 anti-HIV, 959 antifungal, 80 antiparasitic and 185 anticancer peptides. Newly annotated are AMPs with antibiofilm, antimalarial, anti-protist, insecticidal, spermicidal, chemotactic, wound healing, antioxidant and protease inhibiting properties. We also describe other searchable annotations, including target pathogens, molecule-binding partners, post-translational modifications and animal models. Amino acid profiles or signatures of natural AMPs are important for peptide classification, prediction and design. Finally, we summarize various database applications in research and education. PMID:26602694

  10. APD3: the antimicrobial peptide database as a tool for research and education

    PubMed Central

    Wang, Guangshun; Li, Xia; Wang, Zhe

    2016-01-01

    The antimicrobial peptide database (APD, http://aps.unmc.edu/AP/) is an original database initially online in 2003. The APD2 (2009 version) has been regularly updated and further expanded into the APD3. This database currently focuses on natural antimicrobial peptides (AMPs) with defined sequence and activity. It includes a total of 2619 AMPs with 261 bacteriocins from bacteria, 4 AMPs from archaea, 7 from protists, 13 from fungi, 321 from plants and 1972 animal host defense peptides. The APD3 contains 2169 antibacterial, 172 antiviral, 105 anti-HIV, 959 antifungal, 80 antiparasitic and 185 anticancer peptides. Newly annotated are AMPs with antibiofilm, antimalarial, anti-protist, insecticidal, spermicidal, chemotactic, wound healing, antioxidant and protease inhibiting properties. We also describe other searchable annotations, including target pathogens, molecule-binding partners, post-translational modifications and animal models. Amino acid profiles or signatures of natural AMPs are important for peptide classification, prediction and design. Finally, we summarize various database applications in research and education. PMID:26602694

  11. Existing data sources for clinical epidemiology: The North Denmark Bacteremia Research Database

    PubMed Central

    Schønheyder, Henrik C; Søgaard, Mette

    2010-01-01

    Bacteremia is associated with high morbidity and mortality. Improving prevention and treatment requires better knowledge of the disease and its prognosis. However, in order to study the entire spectrum of bacteremia patients, we need valid sources of information, prospective data collection, and complete follow-up. In North Denmark Region, all patients diagnosed with bacteremia have been registered in a population-based database since 1981. The information has been recorded prospectively since 1992 and the main variables are: the patient’s unique civil registration number, date of sampling the first positive blood culture, date of admission, clinical department, date of notification of growth, place of acquisition, focus of infection, microbiological species, antibiogram, and empirical antimicrobial treatment. During the time from 1981 to 2008, information on 22,556 cases of bacteremia has been recorded. The civil registration number makes it possible to link the database to other medical databases and thereby build large cohorts with detailed longitudinal data that include hospital histories since 1977, comorbidity data, and complete follow-up of survival. The database is suited for epidemiological research and, presently, approximately 60 studies have been published. Other Danish departments of clinical microbiology have recently started to record the same information and a population base of 2.3 million will be available for future studies. PMID:20865114

  12. Adjusting for COPD severity in database research: developing and validating an algorithm

    PubMed Central

    Goossens, Lucas MA; Baker, Christine L; Monz, Brigitta U; Zou, Kelly H; Mölken, Maureen PMH Rutten-van

    2011-01-01

    Purpose When comparing chronic obstructive lung disease (COPD) interventions in database research, it is important to adjust for severity. Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines grade severity according to lung function. Most databases lack data on lung function. Previous database research has approximated COPD severity using demographics and healthcare utilization. This study aims to derive an algorithm for COPD severity using baseline data from a large respiratory trial (UPLIFT). Methods Partial proportional odds logit models were developed for probabilities of being in GOLD stages II, III and IV. Concordance between predicted and observed stage was assessed using kappa-statistics. Models were estimated in a random selection of 2/3 of patients and validated in the remainder. The analysis was repeated in a subsample with a balanced distribution across severity stages. Univariate associations of COPD severity with the covariates were tested as well. Results More severe COPD was associated with being male and younger, having quit smoking, lower BMI, osteoporosis, hospitalizations, using certain medications, and oxygen. After adjusting for these variables, co-morbidities, previous healthcare resource use (eg, emergency room, hospitalizations) and inhaled corticosteroids, xanthines, or mucolytics were no longer independently associated with COPD severity, although they were in univariate tests. The concordance was poor (kappa = 0.151) and only slightly better in the balanced sample (kappa = 0.215). Conclusion COPD severity cannot be reliably predicted from demographics and healthcare use. This limitation should be considered when interpreting findings from database studies, and additional research should explore other methods to account for COPD severity. PMID:22259243

  13. Fine-grained policy control in U.S. Army Research Laboratory (ARL) multimodal signatures database

    NASA Astrophysics Data System (ADS)

    Bennett, Kelly; Grueneberg, Keith; Wood, David; Calo, Seraphin

    2014-06-01

    The U.S. Army Research Laboratory (ARL) Multimodal Signatures Database (MMSDB) consists of a number of colocated relational databases representing a collection of data from various sensors. Role-based access to this data is granted to external organizations such as DoD contractors and other government agencies through a client Web portal. In the current MMSDB system, access control is only at the database and firewall level. In order to offer finer grained security, changes to existing user profile schemas and authentication mechanisms are usually needed. In this paper, we describe a software middleware architecture and implementation that allows fine-grained access control to the MMSDB at a dataset, table, and row level. Result sets from MMSDB queries issued in the client portal are filtered with the use of a policy enforcement proxy, with minimal changes to the existing client software and database. Before resulting data is returned to the client, policies are evaluated to determine if the user or role is authorized to access the data. Policies can be authored to filter data at the row, table or column level of a result set. The system uses various technologies developed in the International Technology Alliance in Network and Information Science (ITA) for policy-controlled information sharing and dissemination1. Use of the Policy Management Library provides a mechanism for the management and evaluation of policies to support finer grained access to the data in the MMSDB system. The GaianDB is a policy-enabled, federated database that acts as a proxy between the client application and the MMSDB system.

  14. Validation of Acute Myocardial Infarction Cases in the National Health Insurance Research Database in Taiwan

    PubMed Central

    Cheng, Ching-Lan; Lee, Cheng-Han; Chen, Po-Sheng; Li, Yi-Heng; Lin, Swu-Jane; Yang, Yea-Huei Kao

    2014-01-01

    Background The aim of this study was to determine the validity of acute myocardial infarction (AMI) diagnosis coding in the National Health Insurance Research Database (NHIRD) by cross-comparisons of discharge diagnoses listed in the NHIRD with those in the medical records obtained from a medical center in Taiwan. Methods This was a cross-sectional study comparing records in the NHIRD and discharge notes in one medical center (DNMC) in the year 2008. Positive predictive values (PPVs) for AMI diagnoses were evaluated by reviewing the relevant clinical and laboratory data recorded in the discharge notes of the medical center. Agreement in comorbidities, cardiac procedures, and antiplatelet agent (aspirin or clopidogrel) prescriptions between the two databases was evaluated. Results We matched 341 cases of AMI hospitalizations from the two databases, and 338 cases underwent complete chart review. Of these 338 AMI cases, 297 were confirmed with clinical and lab data, which yielded a PPV of 0.88. The consistency rate for coronary intervention, stenting, and antiplatelet prescription at admission was high, yielding a PPV over 0.90. The percentage of consistency in comorbidity diagnoses was 95.9% (324/338) among matched AMI cases. Conclusions The NHIRD appears to be a valid resource for population research in cardiovascular diseases. PMID:25174915

  15. Computer-Aided Systems Engineering for Flight Research Projects Using a Workgroup Database

    NASA Technical Reports Server (NTRS)

    Mizukami, Masahi

    2004-01-01

    An online systems engineering tool for flight research projects has been developed through the use of a workgroup database. Capabilities are implemented for typical flight research systems engineering needs in document library, configuration control, hazard analysis, hardware database, requirements management, action item tracking, project team information, and technical performance metrics. Repetitive tasks are automated to reduce workload and errors. Current data and documents are instantly available online and can be worked on collaboratively. Existing forms and conventional processes are used, rather than inventing or changing processes to fit the tool. An integrated tool set offers advantages by automatically cross-referencing data, minimizing redundant data entry, and reducing the number of programs that must be learned. With a simplified approach, significant improvements are attained over existing capabilities for minimal cost. By using a workgroup-level database platform, personnel most directly involved in the project can develop, modify, and maintain the system, thereby saving time and money. As a pilot project, the system has been used to support an in-house flight experiment. Options are proposed for developing and deploying this type of tool on a more extensive basis.

  16. USDA-ARS Riesel Watersheds, Riesel, Texas, USA: Water quality research database

    NASA Astrophysics Data System (ADS)

    Harmel, R. Daren; Haney, Richard L.; Smith, Douglas R.; White, Michael; King, Kevin W.

    2014-10-01

    The 75 year legacy database including discharge, sediment loss, land management, and meteorological data for the USDA-ARS Riesel Watersheds, Riesel, TX, USA has been available on the web for more than a decade (www.ars.usda.gov/spa/hydro-data) and used in numerous studies and publications; however, only recently have these data been added to the Sustaining the Earth's Watersheds, Agricultural Research Data System (STEWARDS) database (www.nrrig.mwa.ars.usda.gov/stewards/stewards.html). In addition, water quality data including dissolved inorganic N and P compounds measured from more than 1000 storm runoff events, 1300 base flow sampling events (lateral subsurface return flow or seepage flow), and 157 precipitation events through 2012 were added. The objectives of this manuscript are to present relevant background information on these data, summarize the data collection and analysis methodology, present the measured data along with cursory analyses, and convey the commitment of the USDA-ARS Riesel Watersheds to long-term data accessibility and database enhancement for water quality data and research.

  17. Human health risk assessment database, 'the NHSRC toxicity value database': Supporting the risk assessment process at US EPA's National Homeland Security Research Center

    SciTech Connect

    Moudgal, Chandrika J.

    2008-11-15

    The toxicity value database of the United States Environmental Protection Agency's (EPA) National Homeland Security Research Center has been in development since 2004. The toxicity value database includes a compilation of agent property, toxicity, dose-response, and health effects data for 96 agents: 84 chemical and radiological agents and 12 biotoxins. The database is populated with multiple toxicity benchmark values and agent property information from secondary sources, with web links to the secondary sources, where available. A selected set of primary literature citations and associated dose-response data are also included. The toxicity value database offers a powerful means to quickly and efficiently gather pertinent toxicity and dose-response data for a number of agents that are of concern to the nation's security. This database, in conjunction with other tools, will play an important role in understanding human health risks, and will provide a means for risk assessors and managers to make quick and informed decisions on the potential health risks and determine appropriate responses (e.g., cleanup) to agent release. A final, stand alone MS ACESSS working version of the toxicity value database was completed in November, 2007.

  18. Modeling the High Speed Research Cycle 2B Longitudinal Aerodynamic Database Using Multivariate Orthogonal Functions

    NASA Technical Reports Server (NTRS)

    Morelli, E. A.; Proffitt, M. S.

    1999-01-01

    The data for longitudinal non-dimensional, aerodynamic coefficients in the High Speed Research Cycle 2B aerodynamic database were modeled using polynomial expressions identified with an orthogonal function modeling technique. The discrepancy between the tabular aerodynamic data and the polynomial models was tested and shown to be less than 15 percent for drag, lift, and pitching moment coefficients over the entire flight envelope. Most of this discrepancy was traced to smoothing local measurement noise and to the omission of mass case 5 data in the modeling process. A simulation check case showed that the polynomial models provided a compact and accurate representation of the nonlinear aerodynamic dependencies contained in the HSR Cycle 2B tabular aerodynamic database.

  19. High Tech High School Interns Develop a Mid-Ocean Ridge Database for Research and Education

    NASA Astrophysics Data System (ADS)

    Staudigel, D.; Delaney, R.; Staudigel, H.; Koppers, A. A.; Miller, S. P.

    2004-12-01

    Mid-ocean ridges (MOR) represent one of the most important geographical and geological features on planet Earth. MORs are the locations where plates spread apart, they are the locations of the majority of the Earths' volcanoes that harbor some of the most extreme life forms. These concepts attract much research, but mid-ocean ridges are still effectively underrepresented in the Earth science class rooms. As two High Tech High School students, we began an internship at Scripps to develop a database for mid-ocean ridges as a resource for science and education. This Ridge Catalog will be accessible via http://earthref.org/databases/RC/ and applies a similar structure, design and data archival principle as the Seamount Catalog under EarthRef.org. Major research goals of this project include the development of (1) an archival structure for multibeam and sidescan data, standard bathymetric maps (including ODP-DSDP drill site and dredge locations) or any other arbitrary digital objects relating to MORs, and (2) to compile a global data set for some of the most defining characteristics of every ridge segment including ridge segment length, depth and azimuth and half spreading rates. One of the challenges included the need of making MOR data useful to the scientist as well as the teacher in the class room. Since the basic structure follows the design of the Seamount Catalog closely, we could move our attention to the basic data population of the database. We have pulled together multibeam data for the MOR segments from various public archives (SIOExplorer, SIO-GDC, NGDC, Lamont), and pre-processed it for public use. In particular, we have created individual bathymetric maps for each ridge segment, while merging the multibeam data with global satellite bathymetry data from Smith & Sandwell (1997). The global scale of this database will give it the ability to be used for any number of applications, from cruise planning to data

  20. Solubility Database

    National Institute of Standards and Technology Data Gateway

    SRD 106 IUPAC-NIST Solubility Database (Web, free access)   These solubilities are compiled from 18 volumes (Click here for List) of the International Union for Pure and Applied Chemistry(IUPAC)-NIST Solubility Data Series. The database includes liquid-liquid, solid-liquid, and gas-liquid systems. Typical solvents and solutes include water, seawater, heavy water, inorganic compounds, and a variety of organic compounds such as hydrocarbons, halogenated hydrocarbons, alcohols, acids, esters and nitrogen compounds. There are over 67,500 solubility measurements and over 1800 references.

  1. Database and Registry Research in Orthopaedic Surgery: Part I: Claims-Based Data.

    PubMed

    Pugely, Andrew J; Martin, Christopher T; Harwood, Jared; Ong, Kevin L; Bozic, Kevin J; Callaghan, John J

    2015-08-01

    The use of large-scale national databases for observational research in orthopaedic surgery has grown substantially in the last decade, and the data sets can be grossly categorized as either administrative claims or clinical registries. Administrative claims data comprise the billing records associated with the delivery of health-care services. Orthopaedic researchers have used both government and private claims to describe temporal trends, geographic variation, disparities, complications, outcomes, and resource utilization associated with both musculoskeletal disease and treatment. Medicare claims comprise one of the most robust data sets used to perform orthopaedic research, with >45 million beneficiaries. The U.S. government, through the Centers for Medicare & Medicaid Services, often uses these data to drive changes in health policy. Private claims data used in orthopaedic research often comprise more heterogeneous patient demographic samples, but allow longitudinal analysis similar to that offered by Medicare claims. Discharge databases, such as the U.S. National Inpatient Sample, provide a wide national sampling of inpatient hospital stays from all payers and allow analysis of associated adverse events and resource utilization. Administrative claims data benefit from the high patient numbers obtained through a majority of hospitals. Using claims, it is possible to follow patients longitudinally throughout encounters irrespective of the location of the institution delivering health care. Some disadvantages include lack of precision of ICD-9 (International Classification of Diseases, Ninth Revision) coding schemes. Much of these data are expensive to purchase, complicated to organize, and labor-intensive to manipulate--often requiring trained specialists for analysis. Given the changing health-care environment, it is likely that databases will provide valuable information that has the potential to influence clinical practice improvement and health policy for years to come. PMID:26246263

  2. Conference Proceedings: “Down Syndrome: National Conference on Patient Registries, Research Databases, and Biobanks”

    PubMed Central

    Oster-Granite, Mary Lou; Parisi, Melissa A.; Abbeduto, Leonard; Berlin, Dorit S.; Bodine, Cathy; Bynum, Dana; Capone, George; Collier, Elaine; Hall, Dan; Kaeser, Lisa; Kaufmann, Petra; Krischer, Jeffrey; Livingston, Michelle; McCabe, Linda L.; Pace, Jill; Pfenninger, Karl; Rasmussen, Sonja A.; Reeves, Roger H.; Rubinstein, Yaffa; Sherman, Stephanie; Terry, Sharon F.; Whitten, Michelle Sie; Williams, Stephen; McCabe, Edward R.B.; Maddox, Yvonne T.

    2011-01-01

    A December 2010 meeting, “Down Syndrome: National Conference on Patient Registries, Research Databases, and Biobanks,” was jointly sponsored by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) at the National Institutes of Health (NIH) in Bethesda, MD, and the Global Down Syndrome Foundation (GDSF)/Linda Crnic Institute for Down Syndrome based in Denver, CO. Approximately 70 attendees and organizers from various advocacy groups, federal agencies (Centers for Disease Control and Prevention, and various NIH Institutes, Centers, and Offices), members of industry, clinicians, and researchers from various academic institutions were greeted by Drs. Yvonne Maddox, Deputy Director of NICHD, and Edward McCabe, Executive Director of the Linda Crnic Institute for Down Syndrome. They charged the participants to focus on the separate issues of contact registries, research databases, and biobanks through both podium presentations and breakout session discussions. Among the breakout groups for each of the major sessions, participants were asked to generate responses to questions posed by the organizers concerning these three research resources as they related to Down syndrome and then to report back to the group at large with a summary of their discussions. This report represents a synthesis of the discussions and suggested approaches formulated by the group as a whole. PMID:21835664

  3. Plasma Proteome Database as a resource for proteomics research: 2014 update.

    PubMed

    Nanjappa, Vishalakshi; Thomas, Joji Kurian; Marimuthu, Arivusudar; Muthusamy, Babylakshmi; Radhakrishnan, Aneesha; Sharma, Rakesh; Ahmad Khan, Aafaque; Balakrishnan, Lavanya; Sahasrabuddhe, Nandini A; Kumar, Satwant; Jhaveri, Binit Nitinbhai; Sheth, Kaushal Vinaykumar; Kumar Khatana, Ramesh; Shaw, Patrick G; Srikanth, Srinivas Manda; Mathur, Premendu P; Shankar, Subramanian; Nagaraja, Dindagur; Christopher, Rita; Mathivanan, Suresh; Raju, Rajesh; Sirdeshmukh, Ravi; Chatterjee, Aditi; Simpson, Richard J; Harsha, H C; Pandey, Akhilesh; Prasad, T S Keshava

    2014-01-01

    Plasma Proteome Database (PPD; http://www.plasmaproteomedatabase.org/) was initially described in the year 2005 as a part of Human Proteome Organization's (HUPO's) pilot initiative on Human Plasma Proteome Project. Since then, improvements in proteomic technologies and increased throughput have led to identification of a large number of novel plasma proteins. To keep up with this increase in data, we have significantly enriched the proteomic information in PPD. This database currently contains information on 10,546 proteins detected in serum/plasma of which 3784 have been reported in two or more studies. The latest version of the database also incorporates mass spectrometry-derived data including experimentally verified proteotypic peptides used for multiple reaction monitoring assays. Other novel features include published plasma/serum concentrations for 1278 proteins along with a separate category of plasma-derived extracellular vesicle proteins. As plasma proteins have become a major thrust in the field of biomarkers, we have enabled a batch-based query designated Plasma Proteome Explorer, which will permit the users in screening a list of proteins or peptides against known plasma proteins to assess novelty of their data set. We believe that PPD will facilitate both clinical and basic research by serving as a comprehensive reference of plasma proteins in humans and accelerate biomarker discovery and translation efforts. PMID:24304897

  4. Massive Scale Cyber Traffic Analysis: A Driver for Graph Database Research

    SciTech Connect

    Joslyn, Cliff A.; Choudhury, S.; Haglin, David J.; Howe, Bill; Nickless, William K.; Olsen, Bryan K.

    2013-06-19

    We describe the significance and prominence of network traffic analysis (TA) as a graph- and network-theoretical domain for advancing research in graph database systems. TA involves observing and analyzing the connections between clients, servers, hosts, and actors within IP networks, both at particular times and as extended over times. Towards that end, NetFlow (or more generically, IPFLOW) data are available from routers and servers which summarize coherent groups of IP packets flowing through the network. IPFLOW databases are routinely interrogated statistically and visualized for suspicious patterns. But the ability to cast IPFLOW data as a massive graph and query it interactively, in order to e.g.\\ identify connectivity patterns, is less well advanced, due to a number of factors including scaling, and their hybrid nature combining graph connectivity and quantitative attributes. In this paper, we outline requirements and opportunities for graph-structured IPFLOW analytics based on our experience with real IPFLOW databases. Specifically, we describe real use cases from the security domain, cast them as graph patterns, show how to express them in two graph-oriented query languages SPARQL and Datalog, and use these examples to motivate a new class of "hybrid" graph-relational systems.

  5. FmMDb: A Versatile Database of Foxtail Millet Markers for Millets and Bioenergy Grasses Research

    PubMed Central

    Misra, Gopal; Prasad, Manoj

    2013-01-01

    The prominent attributes of foxtail millet (Setaria italica L.) including its small genome size, short life cycle, inbreeding nature, and phylogenetic proximity to various biofuel crops have made this crop an excellent model system to investigate various aspects of architectural, evolutionary and physiological significances in Panicoid bioenergy grasses. After release of its whole genome sequence, large-scale genomic resources in terms of molecular markers were generated for the improvement of both foxtail millet and its related species. Hence it is now essential to congregate, curate and make available these genomic resources for the benefit of researchers and breeders working towards crop improvement. In view of this, we have constructed the Foxtail millet Marker Database (FmMDb; http://www.nipgr.res.in/foxtail.html), a comprehensive online database for information retrieval, visualization and management of large-scale marker datasets with unrestricted public access. FmMDb is the first database which provides complete marker information to the plant science community attempting to produce elite cultivars of millet and bioenergy grass species, thus addressing global food insecurity. PMID:23951158

  6. FmMDb: a versatile database of foxtail millet markers for millets and bioenergy grasses research.

    PubMed

    B, Venkata Suresh; Muthamilarasan, Mehanathan; Misra, Gopal; Prasad, Manoj

    2013-01-01

    The prominent attributes of foxtail millet (Setaria italica L.) including its small genome size, short life cycle, inbreeding nature, and phylogenetic proximity to various biofuel crops have made this crop an excellent model system to investigate various aspects of architectural, evolutionary and physiological significances in Panicoid bioenergy grasses. After release of its whole genome sequence, large-scale genomic resources in terms of molecular markers were generated for the improvement of both foxtail millet and its related species. Hence it is now essential to congregate, curate and make available these genomic resources for the benefit of researchers and breeders working towards crop improvement. In view of this, we have constructed the Foxtail millet Marker Database (FmMDb; http://www.nipgr.res.in/foxtail.html), a comprehensive online database for information retrieval, visualization and management of large-scale marker datasets with unrestricted public access. FmMDb is the first database which provides complete marker information to the plant science community attempting to produce elite cultivars of millet and bioenergy grass species, thus addressing global food insecurity. PMID:23951158

  7. Administrative Databases in Orthopaedic Research: Pearls and Pitfalls of Big Data.

    PubMed

    Patel, Alpesh A; Singh, Kern; Nunley, Ryan M; Minhas, Shobhit V

    2016-03-01

    The drive for evidence-based decision-making has highlighted the shortcomings of traditional orthopaedic literature. Although high-quality, prospective, randomized studies in surgery are the benchmark in orthopaedic literature, they are often limited by size, scope, cost, time, and ethical concerns and may not be generalizable to larger populations. Given these restrictions, there is a growing trend toward the use of large administrative databases to investigate orthopaedic outcomes. These datasets afford the opportunity to identify a large numbers of patients across a broad spectrum of comorbidities, providing information regarding disparities in care and outcomes, preoperative risk stratification parameters for perioperative morbidity and mortality, and national epidemiologic rates and trends. Although there is power in these databases in terms of their impact, potential problems include administrative data that are at risk of clerical inaccuracies, recording bias secondary to financial incentives, temporal changes in billing codes, a lack of numerous clinically relevant variables and orthopaedic-specific outcomes, and the absolute requirement of an experienced epidemiologist and/or statistician when evaluating results and controlling for confounders. Despite these drawbacks, administrative database studies are fundamental and powerful tools in assessing outcomes on a national scale and will likely be of substantial assistance in the future of orthopaedic research. PMID:26836377

  8. [The development of European Union common research and development policy and programs with special regard to life sciences].

    PubMed

    Pörzse, Gábor

    2009-08-01

    Research and development (R&D) has been playing a leading role in the European Community's history since the very beginning of European integration. Its importance has grown in recent years, after the launch of the Lisbon strategy. Framework programs have always played a considerable part in community research. The aim of their introduction was to fine tune national R&D activities, and to successfully divide research tasks between the Community and the member states. The Community, from the very outset, has acknowledged the importance of life sciences. It is no coincidence that life sciences have become the second biggest priority in the last two framework programs. This study provides a historical, and at the same time analytical and evaluative review of community R&D policy and activity from the starting point of its development until the present day. It examines in detail how the changes in structure, conditional system, regulations and priorities of the framework programs have followed the formation of social and economic needs. The paper puts special emphasis on the analysis of the development of life science research, presenting how they have met the challenges of the age, and how they have been built into the framework programs. Another research area of the present study is to elaborate how successfully Hungarian researchers have been joining the community research, especially the framework programs in the field of life sciences. To answer these questions, it was essential to survey, process and analyze the data available in the national and European public and closed databases. Contrary to the previous documents, this analysis doesn't concentrate on the political and scientific background. It outlines which role community research has played in sustainable social and economic development and competitiveness, how it has supported common policies and how the processes of integration have been deepening. Besides, the present paper offers a complete review of the given field, from its foundation up until the present day, by elaborating the newest initiatives and ideas for the future. This work is also novel from the point of view of the given professional field, the life sciences in the framework programs, and processing and evaluating of data of Hungarian participation in the 5th and 6th framework programs in the field of life sciences. PMID:19632918

  9. Interacting with the National Database for Autism Research (NDAR) via the LONI Pipeline Workflow Environment

    PubMed Central

    Torgerson, Carinna M.; Quinn, Catherine; Dinov, Ivo; Liu, Zhizhong; Petrosyan, Petros; Pelphrey, Kevin; Haselgrove, Christian; Kennedy, David N.; Toga, Arthur W.; Van Horn, John Darrell

    2015-01-01

    The National Database for Autism Research (NDAR) seeks to gather, curate, and make openly available neuroimaging data from NIH-funded studies of autism spectrum disorder (ASD). NDAR has recently made its database accessible through the LONI Pipeline processing environment to enable large-scale analyses of cortical architecture and function via local, cluster, or “cloud”-based computing resources. This presents a unique opportunity to overcome many of the customary limitations to fostering biomedical neuroimaging as a science of discovery. Providing open access to primary neuroimaging data, workflow methods, and high-performance computing will increase uniformity in data collection protocols, encourage greater reliability of published data, results replication, and broaden the range of researchers now able to perform larger studies than ever before. To illustrate the use of NDAR and LONI Pipeline for performing several commonly performed neuroimaging processing steps and analyses, this paper presents example workflows useful for ASD neuroimaging researchers seeking to begin using this valuable combination of online data and computational resources. PMID:25666423

  10. The Corvids Literature Database-500 years of ornithological research from a crow's perspective.

    PubMed

    Droege, Gabriele; Töpfer, Till

    2016-01-01

    Corvids (Corvidae) play a major role in ornithological research. Because of their worldwide distribution, diversity and adaptiveness, they have been studied extensively. The aim of the Corvids Literature Database (CLD, http://www.corvids.de/cld) is to record all publications (citation format) on all extant and extinct Crows, Ravens, Jays and Magpies worldwide and tag them with specific keywords making them available for researchers worldwide. The self-maintained project started in 2006 and today comprises 8000 articles, spanning almost 500 years. The CLD covers publications from 164 countries, written in 36 languages and published by 8026 authors in 1503 journals (plus books, theses and other publications). Forty-nine percent of all records are available online as full-text documents or deposited in the physical CLD archive. The CLD contains 442 original corvid descriptions. Here, we present a metadata assessment of articles recorded in the CLD including a gap analysis and prospects for future research.Database URL: http://www.corvids.de/cld. PMID:26868053

  11. The Government Finance Database: A Common Resource for Quantitative Research in Public Financial Analysis

    PubMed Central

    Pierson, Kawika; Hand, Michael L.; Thompson, Fred

    2015-01-01

    Quantitative public financial management research focused on local governments is limited by the absence of a common database for empirical analysis. While the U.S. Census Bureau distributes government finance data that some scholars have utilized, the arduous process of collecting, interpreting, and organizing the data has led its adoption to be prohibitive and inconsistent. In this article we offer a single, coherent resource that contains all of the government financial data from 1967-2012, uses easy to understand natural-language variable names, and will be extended when new data is available. PMID:26107821

  12. SPIN Query Tools for De-identified Research on a Humongous Database

    PubMed Central

    McDonald, Clement J.; Dexter, Paul; Schadow, Gunther; Chueh, Henry C.; Abernathy, Greg; Hook, John; Blevins, Lonnie; Overhage, J. Marc; Berman, Jules J.

    2005-01-01

    The Shared Pathology Informatics Network (SPIN), a research initiative of the National Cancer Institute, will allow for the retrieval of more than 4 million pathology reports and specimens. In this paper, we describe the special query tool as developed for the Indianapolis/Regenstrief SPIN node, integrated into the ever-expanding Indiana Network for Patient care (INPC). This query tool allows for the retrieval of de-identified data sets using complex logic, auto-coded final diagnoses, and intrinsically supports multiple types of statistical analyses. The new SPIN/INPC database represents a new generation of the Regenstrief Medical Record system – a centralized, but federated system of repositories. PMID:16779093

  13. The Government Finance Database: A Common Resource for Quantitative Research in Public Financial Analysis.

    PubMed

    Pierson, Kawika; Hand, Michael L; Thompson, Fred

    2015-01-01

    Quantitative public financial management research focused on local governments is limited by the absence of a common database for empirical analysis. While the U.S. Census Bureau distributes government finance data that some scholars have utilized, the arduous process of collecting, interpreting, and organizing the data has led its adoption to be prohibitive and inconsistent. In this article we offer a single, coherent resource that contains all of the government financial data from 1967-2012, uses easy to understand natural-language variable names, and will be extended when new data is available. PMID:26107821

  14. SPIN query tools for de-identified research on a humongous database.

    PubMed

    McDonald, Clement J; Dexter, Paul; Schadow, Gunther; Chueh, Henry C; Abernathy, Greg; Hook, John; Blevins, Lonnie; Overhage, J Marc; Berman, Jules J

    2005-01-01

    The Shared Pathology Informatics Network (SPIN), a research initiative of the National Cancer Institute, will allow for the retrieval of more than 4 million pathology reports and specimens. In this paper, we describe the special query tool as developed for the Indianapolis/Regenstrief SPIN node, integrated into the ever-expanding Indiana Network for Patient care (INPC). This query tool allows for the retrieval of de-identified data sets using complex logic, auto-coded final diagnoses, and intrinsically supports multiple types of statistical analyses. The new SPIN/INPC database represents a new generation of the Regenstrief Medical Record system - a centralized, but federated system of repositories. PMID:16779093

  15. Lung Image Database Consortium: Developing a Resource for the Medical Imaging Research Community

    Cancer.gov

    Samuel G. Armato III, PhD, Geoffrey McLennan, MD, PhD, Michael F. McNitt-Gray, PhD, Charles R. Meyer, PhD, David Yankelevitz, MD, Denise R. Aberle, MD, Claudia I. Henschke, MD, PhD, Eric A. Hoffman, PhD, Ella A. Kazerooni, MD, MS, Heber MacMahon, MD, Anthony P. Reeves, PhD, Barbara Y. Croft, PhD, Laurence P. Clarke, PhD, For the Lung Image Database Consortium Research Group, Radiology 2004; 232: 739-748.

  16. Labour Market Outcomes of Vocational Education in Europe: Evidence from the European Union Labour Force Survey. Research Paper No 32

    ERIC Educational Resources Information Center

    Cedefop - European Centre for the Development of Vocational Training, 2013

    2013-01-01

    This report focuses on the outcomes of vocational education and, in particular, on the transition from education to work in the current employment situation for young adults in the European Union. Using anonymised microdata from the EU labour force survey 2009 ad hoc module, this is one of the first studies to undertake a large cross-country…

  17. National Database for Autism Research (NDAR): Big Data Opportunities for Health Services Research and Health Technology Assessment.

    PubMed

    Payakachat, Nalin; Tilford, J Mick; Ungar, Wendy J

    2016-02-01

    The National Database for Autism Research (NDAR) is a US National Institutes of Health (NIH)-funded research data repository created by integrating heterogeneous datasets through data sharing agreements between autism researchers and the NIH. To date, NDAR is considered the largest neuroscience and genomic data repository for autism research. In addition to biomedical data, NDAR contains a large collection of clinical and behavioral assessments and health outcomes from novel interventions. Importantly, NDAR has a global unique patient identifier that can be linked to aggregated individual-level data for hypothesis generation and testing, and for replicating research findings. As such, NDAR promotes collaboration and maximizes public investment in the original data collection. As screening and diagnostic technologies as well as interventions for children with autism are expensive, health services research (HSR) and health technology assessment (HTA) are needed to generate more evidence to facilitate implementation when warranted. This article describes NDAR and explains its value to health services researchers and decision scientists interested in autism and other mental health conditions. We provide a description of the scope and structure of NDAR and illustrate how data are likely to grow over time and become available for HSR and HTA. PMID:26446859

  18. Scientific Research Database of the 2008 Ms8.0 Wenchuan Earthquake

    NASA Astrophysics Data System (ADS)

    Liang, C.; Yang, Y.; Yu, Y.

    2013-12-01

    Nearly 5 years after the 2008 Ms8.0 Wenchuan Earthquake, the Ms7.0 Lushan earthquake stroke 70km away along the same fault system. Given the tremendous life loss and property damages as well as the short time and distance intervals between the two large magnitude events, the scientific probing into their causing factors and future seismic activities in the nearby region will continue to be in the center of earthquake research in China and even the world for years to come. In the past five years, scientists have made significant efforts to study the Wenchuan earthquake from various aspects using different datasets and methods. Their studies cover a variety of topics including seismogenic environment, earthquake precursors, rupture process, co-seismic phenomenon, hazard relief, reservoir induced seismicity and more. These studies have been published in numerous journals in Chinese, English and many other languages. In addition, 54 books regarding to this earthquake have been published. The extremely diversified nature of all publications makes it very difficult and time-consuming, if not impossible, to sort out information needed by individual researcher in an efficient way. An information platform that collects relevant scientific information and makes them accessible in various ways can be very handy. With this mission in mind, the Earthquake Research Group in the Chengdu University of Technology has developed a website www.wceq.org to attack this target: (1) articles published by major journals and books are recorded into a database. Researchers will be able to find articles by topics, journals, publication dates, authors and keywords e.t.c by a few clicks; (2) to fast track the latest developments, researchers can also follow upon updates in the current month, last 90days, 180 days and 365 days by clicking on corresponding links; (3) the modern communication tools such as Facebook, Twitter and their Chinese counterparts are accommodated in this site to share favorite research information with friends; (4) This site also serves as a bridge between readers and authors by providing messaging boards in many forms; (5) we also track relevant meeting presentations, ongoing researches as well as earthquake-related news; (6) furthermore, we also collect publications of earthquakes in the eastern Tibetan plateau and selected ones from other regions for comparison purpose. After nearly one year of operation, the database has been growing steadily with time and the major functionalities have been well developed and stabilized. Up to August 6 2013, totally 847 papers have been collected in our database. Among them 673, 21 and 153 papers are of Wenchuan, Lushan and Tohoko earthquake in interest, respectively. For the Wenchuan earthquake articles, nearly 10%, 20%, 25%,15%, 15% are of studies in seismogenic environment, precursors, rupture process, hazard relief and aftershocks & coseismic events, respectively. Built upon the ever growing database, the next move would be to do more analysis. One ongoing project would be to collect figures from articles that are of special interest to people in the field. A parallel project will also start to extend the database to include Tibetan Plateau studies.

  19. Unions, Solidarity, and Striking

    ERIC Educational Resources Information Center

    Dixon, Marc; Roscigno, Vincent J.; Hodson, Randy

    2004-01-01

    Organizational resources and group solidarity are central foci in literature on social movements generally and worker insurgency specifically. Research, however, seldom deals with both simultaneously and their potential interrelations. In this article, we examine the complex relationships between union organization and worker solidarity relative…

  20. Assessing urology and nephrology research activity in Arab countries using ISI web of science bibliometric database

    PubMed Central

    2014-01-01

    Background Bibliometric analysis is increasingly being used for research assessment. The main objective of this study was to assess research output in Urology and Nephrology subject from the Arab countries. Original scientific articles or reviews published from the 21 Arab countries in “Urology and Nephrology” subject were screened using the ISI Web of Science database. Research productivity was evaluated based on a methodology developed and used in other bibliometric studies by analyzing the annual productivity, names of journals, citations; top 10 active institution and authors as well as country contribution to Urology and Nephrology research. Results Three thousand and seventy six documents in “urology and nephrology” subject category were retrieved from 104 journals. This represents 1.4% of the global research output in “urology and nephrology”. Four hundred and two documents (12.66%) were published in Annales D Urologie Journal. The h-index of the retrieved documents was 57. The total number of citations, at the time of data analysis, was 30401 with an average citation of 9.57 per document. Egypt, with a total publication of 1284 (40.43%) ranked first among the Arab countries in “urology and nephrology” subject category. Mansoura University in Egypt was the most productive institution with a total of 561 (15.33%) documents. Arab researchers collaborated most with researchers from the United States of America (226; 7.12%) in urology and nephrology research. Conclusion The present data reveals a good contribution of some Arab countries to the field of “urology and nephrology”. More efforts are needed by some other Arab countries to bridge the gap in urology and nephrology research. Overall, the quality of urology/nephrology research is considered relatively high as measured by h-index. Cooperation in urology/nephrology research should be encouraged in the Arab world to bridge the gap with that from developed countries. PMID:24758477

  1. Overview of ESSL's severe convective storms research using the European Severe Weather Database ESWD

    NASA Astrophysics Data System (ADS)

    Dotzek, Nikolai; Groenemeijer, Pieter; Feuerstein, Bernold; Holzer, Alois M.

    Severe thunderstorms constitute a major weather hazard in Europe, with an estimated total damage of 5-8 billion euros each year nowadays. Even though there is an upward trend in damage due to increases in vulnerability and possibly also due to climate change impacts, a pan-European database of severe thunderstorm reports in a homogeneous data format did not exist until a few years ago. The development of this European Severe Weather Database (ESWD) provided the final impetus for the establishment of the European Severe Storms Laboratory (ESSL) as a non-profit research organisation in 2006, after having started as an informal network in 2002. Our paper provides an overview of the first research results that have been achieved by ESSL. We start by outlining the reporting practice and quality-control procedure for the database, which has been enhanced by a major software upgrade in the fall of 2008. It becomes apparent that the state of reporting converges to a realistic description of the severe storms climatology, corroborating, for instance, earlier estimates of tornado occurrence in Europe. Nevertheless, a further rise in the number of reported events must be expected, even without the presence of any physical trends. The European tornado and damaging wind intensity distributions as a function of the Fujita scale are quantitatively similar to long-term distributions from the USA, except for a strong underreporting of weak events (F0) that still persists in Europe. In addition, the ESSL has recently proposed a new wind speed scale, the Energy- or " E-scale" which is linked to physical quantities and can be calibrated. Finally, we demonstrate the large potential of ESWD data use for forecast or nowcasting/warning verification purposes.

  2. Food-pics: an image database for experimental research on eating and appetite.

    PubMed

    Blechert, Jens; Meule, Adrian; Busch, Niko A; Ohla, Kathrin

    2014-01-01

    Our current environment is characterized by the omnipresence of food cues. The sight and smell of real foods, but also graphically depictions of appetizing foods, can guide our eating behavior, for example, by eliciting food craving and influencing food choice. The relevance of visual food cues on human information processing has been demonstrated by a growing body of studies employing food images across the disciplines of psychology, medicine, and neuroscience. However, currently used food image sets vary considerably across laboratories and image characteristics (contrast, brightness, etc.) and food composition (calories, macronutrients, etc.) are often unspecified. These factors might have contributed to some of the inconsistencies of this research. To remedy this, we developed food-pics, a picture database comprising 568 food images and 315 non-food images along with detailed meta-data. A total of N = 1988 individuals with large variance in age and weight from German speaking countries and North America provided normative ratings of valence, arousal, palatability, desire to eat, recognizability and visual complexity. Furthermore, data on macronutrients (g), energy density (kcal), and physical image characteristics (color composition, contrast, brightness, size, complexity) are provided. The food-pics image database is freely available under the creative commons license with the hope that the set will facilitate standardization and comparability across studies and advance experimental research on the determinants of eating behavior. PMID:25009514

  3. Food-pics: an image database for experimental research on eating and appetite

    PubMed Central

    Blechert, Jens; Meule, Adrian; Busch, Niko A.; Ohla, Kathrin

    2014-01-01

    Our current environment is characterized by the omnipresence of food cues. The sight and smell of real foods, but also graphically depictions of appetizing foods, can guide our eating behavior, for example, by eliciting food craving and influencing food choice. The relevance of visual food cues on human information processing has been demonstrated by a growing body of studies employing food images across the disciplines of psychology, medicine, and neuroscience. However, currently used food image sets vary considerably across laboratories and image characteristics (contrast, brightness, etc.) and food composition (calories, macronutrients, etc.) are often unspecified. These factors might have contributed to some of the inconsistencies of this research. To remedy this, we developed food-pics, a picture database comprising 568 food images and 315 non-food images along with detailed meta-data. A total of N = 1988 individuals with large variance in age and weight from German speaking countries and North America provided normative ratings of valence, arousal, palatability, desire to eat, recognizability and visual complexity. Furthermore, data on macronutrients (g), energy density (kcal), and physical image characteristics (color composition, contrast, brightness, size, complexity) are provided. The food-pics image database is freely available under the creative commons license with the hope that the set will facilitate standardization and comparability across studies and advance experimental research on the determinants of eating behavior. PMID:25009514

  4. Evaluating the options for developing databases to support research-based medicine at the NHS Centre for Reviews and Dissemination.

    PubMed

    Glanville, J; Smith, I

    1997-11-01

    The paper presents the results of a questionnaire survey and user interface review group experiments to determine the value and ease of use of the Database of Abstracts of Reviews of Effectiveness (DARE) and the NHS Economic Evaluations Database (NEED). The results are interpreted with other recent studies of the use of electronic databases, including the NHS Research Register User Requirements Specification. The study found that most frequent users of the DARE database tend to use the CD-ROM version. Librarians were found to have the greatest awareness of the databases, with relatively low levels of use by operational NHS Staff. Untrained users found the online databases difficult to access and had erroneous perceptions of the database content which were only realised when queries returned unexpected answers. Experienced users of online information systems tended to want more sophisticated search facilities than inexperienced users. Nearly all users in the review groups wanted to access the databases in conjunction with other information sources, such as the Cochrane Library, Medline and the ACP Journal Club, highlighting the need for cross organisational strategies for the dissemination of research-based information. PMID:9506399

  5. U.S. Department of Agriculture Agricultural Research Service Mahantango Creek Watershed, Pennsylvania, United States: long-term precipitation database

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A long-term precipitation database has been developed by the U.S. Department of Agriculture, Agricultural Research Service, Pasture Systems and Watershed Management Research Unit (PSWMRU) to support intensive hydrologic and water quality research within WE-38, a 7.3 km**2 experimental watershed loca...

  6. Does Reimportation Reduce Price Differences for Prescription Drugs? Lessons from the European Union

    PubMed Central

    Kyle, Margaret K; Allsbrook, Jennifer S; Schulman, Kevin A

    2008-01-01

    Objective To examine the effect of parallel trade on patterns of price dispersion for prescription drugs in the European Union. Data Sources Longitudinal data from an IMS Midas database of prices and units sold for drugs in 36 categories in 30 countries from 1993 through 2004. Study Design The main outcome measures were mean price differentials and other measures of price dispersion within European Union countries compared with within non-European Union countries. Data Collection/Extraction Methods We identified drugs subject to parallel trade using information provided by IMS and by checking membership lists of parallel import trade associations and lists of approved parallel imports. Principal Findings Parallel trade was not associated with substantial reductions in price dispersion in European Union countries. In descriptive and regression analyses, about half of the price differentials exceeded 50 percent in both European Union and non-European Union countries over time, and price distributions among European Union countries did not show a dramatic change concurrent with the adoption of parallel trade. In regression analysis, we found that although price differentials decreased after 1995 in most countries, they decreased less in the European Union than elsewhere. Conclusions Parallel trade for prescription drugs does not automatically reduce international price differences. Future research should explore how other regulatory schemes might lead to different results elsewhere. PMID:18355258

  7. Human genetic research databases and biobanks: towards uniform terminology and Australian best practice.

    PubMed

    Chalmers, Don; Nicol, Dianne

    2008-02-01

    This article examines international best practice for the establishment, maintenance and use of human genetic research databases (HGRDs), particularly focusing on large-scale population biobanks, and considers the measures that should be taken in Australia to comply with this best practice. These HGRDs play a pivotal role in basic research aimed at understanding the basis of human disease at the genetic level, and applied research aimed at putting that basic knowledge into practical application. In particular, the large-scale biobanks are vital research tools in the drive to uncover the causes and consequences of human health and disease. Biobanks are being established at regional, national and international levels throughout the world. Although their governance structures are uniformly complex, some best practices are emerging with regard to consent (particularly consent to future research and withdrawal of consent), privacy and data protection and intellectual property ownership and access. Best practices with regard to benefit-sharing are emerging much more slowly. This article reviews these international best practices with the aim of providing guidance for the development of appropriate regulatory structures in Australia. PMID:18365521

  8. The European internet-based patient and research database for primary immunodeficiencies: update 2011

    PubMed Central

    Gathmann, B; Binder, N; Ehl, S; Kindle, G

    2012-01-01

    In order to build a common data pool and estimate the disease burden of primary immunodeficiencies (PID) in Europe, the European Society for Immunodeficiencies (ESID) has developed an internet-based database for clinical and research data on patients with PID. This database is a platform for epidemiological analyses as well as the development of new diagnostic and therapeutic strategies and the identification of novel disease-associated genes. Since its start in 2004, 13 708 patients from 41 countries have been documented in the ESID database. Common variable immunodeficiency (CVID) represents the most common entity with 2880 patients or 21% of all entries, followed by selective immunoglobulin A (sIgA) deficiency (1424 patients, 10·4%). The total documented prevalence of PID is highest in France, with five patients per 100 000 inhabitants. The highest documented prevalence for a single disease is 1·3 per 100 000 inhabitants for sIgA deficiency in Hungary. The highest reported incidence of PID per 100 000 live births was 16·2 for the period 1999–2002 in France. The highest reported incidence rate for a single disease was 6·7 for sIgA deficiency in Spain for the period 1999–2002. The genetic cause was known in 36·2% of all registered patients. Consanguinity was reported in 8·8%, and 18·5% of patients were reported to be familial cases; 27·9% of patients were diagnosed after the age of 16. We did not observe a significant decrease in the diagnostic delay for most diseases between 1987 and 2010. The most frequently reported long-term medication is immunoglobulin replacement. PMID:22288591

  9. NASA's Astromaterials Database: Enabling Research Through Increased Access to Sample Data, Metadata and Imagery

    NASA Technical Reports Server (NTRS)

    Evans, Cindy; Todd, Nancy

    2014-01-01

    The Astromaterials Acquisition & Curation Office at NASA's Johnson Space Center (JSC) is the designated facility for curating all of NASA's extraterrestrial samples. Today, the suite of collections includes the lunar samples from the Apollo missions, cosmic dust particles falling into the Earth's atmosphere, meteorites collected in Antarctica, comet and interstellar dust particles from the Stardust mission, asteroid particles from Japan's Hayabusa mission, solar wind atoms collected during the Genesis mission, and space-exposed hardware from several missions. To support planetary science research on these samples, JSC's Astromaterials Curation Office hosts NASA's Astromaterials Curation digital repository and data access portal [http://curator.jsc.nasa.gov/], providing descriptions of the missions and collections, and critical information about each individual sample. Our office is designing and implementing several informatics initiatives to better serve the planetary research community. First, we are re-hosting the basic database framework by consolidating legacy databases for individual collections and providing a uniform access point for information (descriptions, imagery, classification) on all of our samples. Second, we continue to upgrade and host digital compendia that summarize and highlight published findings on the samples (e.g., lunar samples, meteorites from Mars). We host high resolution imagery of samples as it becomes available, including newly scanned images of historical prints from the Apollo missions. Finally we are creating plans to collect and provide new data, including 3D imagery, point cloud data, micro CT data, and external links to other data sets on selected samples. Together, these individual efforts will provide unprecedented digital access to NASA's Astromaterials, enabling preservation of the samples through more specific and targeted requests, and supporting new planetary science research and collaborations on the samples.

  10. Literate Practices in a Modern Credit Union.

    ERIC Educational Resources Information Center

    Keller-Cohen, Deborah

    1987-01-01

    Drawing on research regarding a midwestern credit union, factors characterizing why and how credit unions and their members use credit union documents are discussed in regard to: characteristics of document availability; structure of interactions in which documents are used; attitudes and beliefs about the documents; and functions of documents.…

  11. Potential identification of pediatric asthma patients within pediatric research database using low rank matrix decomposition

    PubMed Central

    2013-01-01

    Asthma is a prevalent disease in pediatric patients and most of the cases begin at very early years of life in children. Early identification of patients at high risk of developing the disease can alert us to provide them the best treatment to manage asthma symptoms. Often evaluating patients with high risk of developing asthma from huge data sets (e.g., electronic medical record) is challenging and very time consuming, and lack of complex analysis of data or proper clinical logic determination might produce invalid results and irrelevant treatments. In this article, we used data from the Pediatric Research Database (PRD) to develop an asthma prediction model from past All Patient Refined Diagnosis Related Groupings (APR-DRGs) coding assignments. The knowledge gleamed in this asthma prediction model, from both routinely use by physicians and experimental findings, will become fused into a knowledge-based database for dissemination to those involved with asthma patients. Success with this model may lead to expansion with other diseases. PMID:24073842

  12. CottonGen: a genomics, genetics and breeding database for cotton research

    PubMed Central

    Yu, Jing; Jung, Sook; Cheng, Chun-Huai; Ficklin, Stephen P.; Lee, Taein; Zheng, Ping; Jones, Don; Percy, Richard G.; Main, Dorrie

    2014-01-01

    CottonGen (http://www.cottongen.org) is a curated and integrated web-based relational database providing access to publicly available genomic, genetic and breeding data for cotton. CottonGen supercedes CottonDB and the Cotton Marker Database, with enhanced tools for easier data sharing, mining, visualization and data retrieval of cotton research data. CottonGen contains annotated whole genome sequences, unigenes from expressed sequence tags (ESTs), markers, trait loci, genetic maps, genes, taxonomy, germplasm, publications and communication resources for the cotton community. Annotated whole genome sequences of Gossypium raimondii are available with aligned genetic markers and transcripts. These whole genome data can be accessed through genome pages, search tools and GBrowse, a popular genome browser. Most of the published cotton genetic maps can be viewed and compared using CMap, a comparative map viewer, and are searchable via map search tools. Search tools also exist for markers, quantitative trait loci (QTLs), germplasm, publications and trait evaluation data. CottonGen also provides online analysis tools such as NCBI BLAST and Batch BLAST. PMID:24203703

  13. The human studies database project: federating human studies design data using the ontology of clinical research.

    PubMed

    Sim, Ida; Carini, Simona; Tu, Samson; Wynden, Rob; Pollock, Brad H; Mollah, Shamim A; Gabriel, Davera; Hagler, Herbert K; Scheuermann, Richard H; Lehmann, Harold P; Wittkowski, Knut M; Nahm, Meredith; Bakken, Suzanne

    2010-01-01

    Human studies, encompassing interventional and observational studies, are the most important source of evidence for advancing our understanding of health, disease, and treatment options. To promote discovery, the design and results of these studies should be made machine-readable for large-scale data mining, synthesis, and re-analysis. The Human Studies Database Project aims to define and implement an informatics infrastructure for institutions to share the design of their human studies. We have developed the Ontology of Clinical Research (OCRe) to model study features such as design type, interventions, and outcomes to support scientific query and analysis. We are using OCRe as the reference semantics for federated data sharing of human studies over caGrid, and are piloting this implementation with several Clinical and Translational Science Award (CTSA) institutions. PMID:21347149

  14. Propellant Mass Gauging: Database of Vehicle Applications and Research and Development Studies

    NASA Technical Reports Server (NTRS)

    Dodge, Franklin T.

    2008-01-01

    Gauging the mass of propellants in a tank in low gravity is not a straightforward task because of the uncertainty of the liquid configuration in the tank and the possibility of there being more than one ullage bubble. Several concepts for such a low-gravity gauging system have been proposed, and breadboard or flight-like versions have been tested in normal gravity or even in low gravity, but at present, a flight-proven reliable gauging system is not available. NASA desired a database of the gauging techniques used in current and past vehicles during ascent or under settled conditions, and during short coasting (unpowered) periods, for both cryogenic and storable propellants. Past and current research and development efforts on gauging systems that are believed to be applicable in low-gravity conditions were also desired. This report documents the results of that survey.

  15. The relationship between labor unions and safety in US airlines: Is there a "union effect?"

    NASA Astrophysics Data System (ADS)

    Zapf, Renee Catherine

    Every airline union claims to work for safety and presents anecdotes where greater airline safety has been achieved through union efforts. The effect unionization has on safety outcomes in U.S. commercial airlines, however, wasn't found to be previously tested. Studies have shown that in industries such as coal mining, retail, and construction, unionization does lead to an increase in safety. This study evaluated the safety rates of 15 major US commercial airlines to compare the difference between unionized and non-unionized airlines. These safety rates were compared based on if and how long each airline's pilots and flight attendants have been unionized, to determine if unionization had an effect on safety outcomes. The 15 airlines included in the study identified as operating most of the years between 1990 and 2013, with annual departures averaging over 130,000, available through the Bureau of Transportation Statistics. Accident and Incident information was acquired through the National Transportation Safety Board database. The number of accident and incidents divided by the total departures at each airline was used as the safety rate. Union websites provided information on unionization at the airlines. Due to the complex nature of the aviation industry, a number of confounding factors could have affected the tests, including mergers, route structures, and legislation. To help control for these confounding factors, this study was limited to airlines with a stable presence in the industry over time, which limited the number of airlines included. No significant difference was found between unionized and non-unionized airlines in this study, though the mean safety rate of unionized airlines was found be better than non-unionized airlines. This study did not take into account safety improvements that were union-backed and eventually required at all airlines, regardless of unionization. Due to the large sample size of the small population the difference in safety rate means could be indicative of greater safety in unionized airlines.

  16. Creating a data exchange strategy for radiotherapy research: Towards federated databases and anonymised public datasets

    PubMed Central

    Skripcak, Tomas; Belka, Claus; Bosch, Walter; Brink, Carsten; Brunner, Thomas; Budach, Volker; Büttner, Daniel; Debus, Jürgen; Dekker, Andre; Grau, Cai; Gulliford, Sarah; Hurkmans, Coen; Just, Uwe; Krause, Mechthild; Lambin, Philippe; Langendijk, Johannes A.; Lewensohn, Rolf; Lühr, Armin; Maingon, Philippe; Masucci, Michele; Niyazi, Maximilian; Poortmans, Philip; Simon, Monique; Schmidberger, Heinz; Spezi, Emiliano; Stuschke, Martin; Valentini, Vincenzo; Verheij, Marcel; Whitfield, Gillian; Zackrisson, Björn; Zips, Daniel; Baumann, Michael

    2015-01-01

    Disconnected cancer research data management and lack of information exchange about planned and ongoing research are complicating the utilisation of internationally collected medical information for improving cancer patient care. Rapidly collecting/pooling data can accelerate translational research in radiation therapy and oncology. The exchange of study data is one of the fundamental principles behind data aggregation and data mining. The possibilities of reproducing the original study results, performing further analyses on existing research data to generate new hypotheses or developing computational models to support medical decisions (e.g. risk/benefit analysis of treatment options) represent just a fraction of the potential benefits of medical data-pooling. Distributed machine learning and knowledge exchange from federated databases can be considered as one beyond other attractive approaches for knowledge generation within “Big Data”. Data interoperability between research institutions should be the major concern behind a wider collaboration. Information captured in electronic patient records (EPRs) and study case report forms (eCRFs), linked together with medical imaging and treatment planning data, are deemed to be fundamental elements for large multi-centre studies in the field of radiation therapy and oncology. To fully utilise the captured medical information, the study data have to be more than just an electronic version of a traditional (un-modifiable) paper CRF. Challenges that have to be addressed are data interoperability, utilisation of standards, data quality and privacy concerns, data ownership, rights to publish, data pooling architecture and storage. This paper discusses a framework for conceptual packages of ideas focused on a strategic development for international research data exchange in the field of radiation therapy and oncology. PMID:25458128

  17. Creating a data exchange strategy for radiotherapy research: towards federated databases and anonymised public datasets.

    PubMed

    Skripcak, Tomas; Belka, Claus; Bosch, Walter; Brink, Carsten; Brunner, Thomas; Budach, Volker; Büttner, Daniel; Debus, Jürgen; Dekker, Andre; Grau, Cai; Gulliford, Sarah; Hurkmans, Coen; Just, Uwe; Krause, Mechthild; Lambin, Philippe; Langendijk, Johannes A; Lewensohn, Rolf; Lühr, Armin; Maingon, Philippe; Masucci, Michele; Niyazi, Maximilian; Poortmans, Philip; Simon, Monique; Schmidberger, Heinz; Spezi, Emiliano; Stuschke, Martin; Valentini, Vincenzo; Verheij, Marcel; Whitfield, Gillian; Zackrisson, Björn; Zips, Daniel; Baumann, Michael

    2014-12-01

    Disconnected cancer research data management and lack of information exchange about planned and ongoing research are complicating the utilisation of internationally collected medical information for improving cancer patient care. Rapidly collecting/pooling data can accelerate translational research in radiation therapy and oncology. The exchange of study data is one of the fundamental principles behind data aggregation and data mining. The possibilities of reproducing the original study results, performing further analyses on existing research data to generate new hypotheses or developing computational models to support medical decisions (e.g. risk/benefit analysis of treatment options) represent just a fraction of the potential benefits of medical data-pooling. Distributed machine learning and knowledge exchange from federated databases can be considered as one beyond other attractive approaches for knowledge generation within "Big Data". Data interoperability between research institutions should be the major concern behind a wider collaboration. Information captured in electronic patient records (EPRs) and study case report forms (eCRFs), linked together with medical imaging and treatment planning data, are deemed to be fundamental elements for large multi-centre studies in the field of radiation therapy and oncology. To fully utilise the captured medical information, the study data have to be more than just an electronic version of a traditional (un-modifiable) paper CRF. Challenges that have to be addressed are data interoperability, utilisation of standards, data quality and privacy concerns, data ownership, rights to publish, data pooling architecture and storage. This paper discusses a framework for conceptual packages of ideas focused on a strategic development for international research data exchange in the field of radiation therapy and oncology. PMID:25458128

  18. Oncoshare: Lessons Learned from Building an Integrated Multi-institutional Database for Comparative Effectiveness Research

    PubMed Central

    Weber, Susan C; Seto, Tina; Olson, Cliff; Kenkare, Pragati; Kurian, Allison W.; Das, Amar K.

    2012-01-01

    Comparative effectiveness research (CER) using observational data requires informatics methods for the extraction, standardization, sharing, and integration of data derived from a variety of electronic sources. In the Oncoshare project, we have developed such methods as part of a collaborative multi-institutional CER study of patterns, predictors, and outcome of breast cancer care. In this paper, we present an evaluation of the approaches we undertook and the lessons we learned in building and validating the Oncoshare data resource. Specifically, we determined that 1) the state or regional cancer registry makes the most efficient starting point for determining inclusion of subjects; 2) the data dictionary should be based on existing registry standards, such as Surveillance, Epidemiology and End Results (SEER), when applicable; 3) the Social Security Administration Death Master File (SSA DMF), rather than clinical resources, provides standardized ascertainment of mortality outcomes; and 4) CER database development efforts, despite the immediate availability of electronic data, may take as long as two years to produce validated, reliable data for research. Through our efforts using these methods, Oncoshare integrates complex, longitudinal data from multiple electronic medical records and registries and provides a rich, validated resource for research on oncology care. PMID:23304372

  19. Integrating databases for research on health and performance in small animals and horses in the Nordic countries.

    PubMed

    Egenvall, Agneta; Nødtvedt, Ane; Roepstorff, Lars; Bonnett, Brenda

    2011-01-01

    In a world of limited resources, using existing databases in research is a potentially cost-effective way to increase knowledge, given that correct and meaningful results are gained.Nordic examples of the use of secondary small animal and equine databases include studies based on data from tumour registries, breeding registries, young horse quality contest results, competition data, insurance databases, clinic data, prescription data and hunting ability tests. In spite of this extensive use of secondary databases, integration between databases is less common. The aim of this presentation is to briefly review key papers that exemplify different ways of utilizing data from multiple sources, to highlight the benefits and limitations of the approaches, to discuss key issues/challenges that must be addressed when integrating data and to suggest future directions. Data from pedigree databases have been individually merged with competition data and young horse quality contest data, and true integration has also been done with canine insurance data and with equine clinical data. Data have also been merged on postal code level; i.e. insurance data were merged to a digitized map of Sweden and additional meteorological information added. In addition to all the data quality and validity issues inherent in the use of a single database, additional obstacles arise when combining information from several databases. Loss of individuals due to incorrect or mismatched identifying information can be considerable. If there are any possible biases affecting whether or not individuals can be properly linked, misinformation may result in a further reduction in power. Issues of confidentiality may be more difficult to address across multiple databases. For example, human identity information must be protected, but may be required to ensure valid merging of data. There is a great potential to better address complex issues of health and disease in companion animals and horses by integrating information across existing databases. The challenges outlined in this article should not preclude the ongoing pursuit of this approach. PMID:21999438

  20. U.S. Department of Energy Human Subjects Research Database (HSRD) A model for internal oversight and external transparency

    SciTech Connect

    Oak Ridge Institute for Science and Education

    2012-12-12

    This poster introduces the Department of Energy (DOE) Human Subjects Research Database (HSRD), which contains information on all Department of Energy research projects involving human subjects that: are funded by DOE; are conducted in DOE facilities; are performed by DOE personnel; include current or former DOE or contract personnel.

  1. Exploring the Returns to Continuing Vocational Training in Enterprises. A Review of Research within and Outside of the European Union. CEDEFOP Pahnorama.

    ERIC Educational Resources Information Center

    Barrett, Alan; Hovels, Ben; den Boer, Paul; Kraayvanger, Geert

    The returns on continuing vocational training (CVT) in enterprises were examined through a review of research on the returns on employer-provided training. A search of "Econ Lit," ERIC, and other databases identified more than 90 publications on the topic. Twenty-one publications examining the relationship between training inputs and training…

  2. NOAA's Integrated Tsunami Database: Data for improved forecasts, warnings, research, and risk assessments

    NASA Astrophysics Data System (ADS)

    Stroker, Kelly; Dunbar, Paula; Mungov, George; Sweeney, Aaron; McCullough, Heather; Carignan, Kelly

    2015-04-01

    The National Oceanic and Atmospheric Administration (NOAA) has primary responsibility in the United States for tsunami forecast, warning, research, and supports community resiliency. NOAA's National Geophysical Data Center (NGDC) and co-located World Data Service for Geophysics provide a unique collection of data enabling communities to ensure preparedness and resilience to tsunami hazards. Immediately following a damaging or fatal tsunami event there is a need for authoritative data and information. The NGDC Global Historical Tsunami Database (http://www.ngdc.noaa.gov/hazard/) includes all tsunami events, regardless of intensity, as well as earthquakes and volcanic eruptions that caused fatalities, moderate damage, or generated a tsunami. The long-term data from these events, including photographs of damage, provide clues to what might happen in the future. NGDC catalogs the information on global historical tsunamis and uses these data to produce qualitative tsunami hazard assessments at regional levels. In addition to the socioeconomic effects of a tsunami, NGDC also obtains water level data from the coasts and the deep-ocean at stations operated by the NOAA/NOS Center for Operational Oceanographic Products and Services, the NOAA Tsunami Warning Centers, and the National Data Buoy Center (NDBC) and produces research-quality data to isolate seismic waves (in the case of the deep-ocean sites) and the tsunami signal. These water-level data provide evidence of sea-level fluctuation and possible inundation events. NGDC is also building high-resolution digital elevation models (DEMs) to support real-time forecasts, implemented at 75 US coastal communities. After a damaging or fatal event NGDC begins to collect and integrate data and information from many organizations into the hazards databases. Sources of data include our NOAA partners, the U.S. Geological Survey, the UNESCO Intergovernmental Oceanographic Commission (IOC) and International Tsunami Information Center, Smithsonian Institution's Global Volcanism Program, news organizations, etc. NGDC assesses the data and then works to promptly distribute the data and information. For example, when a major tsunami occurs, all of the related tsunami data are combined into one timely resource, posted in an online report, which includes: 1) event summary; 2) eyewitness and instrumental recordings from preliminary field surveys; 3) regional historical observations including similar past events and effects; 4) observed water heights and calculated tsunami travel times; and 5) near-field effects. This report is regularly updated to incorporate the most recent data and observations. Providing timely access to authoritative data and information ultimately benefits researchers, state officials, the media and the public. This paper will demonstrate the extensive collection of data and how it is used.

  3. Copernicus benefits the Norwegian Satellite Earth Observation Database for Marine and Polar Research

    NASA Astrophysics Data System (ADS)

    Korosov, Anton; Johannessen, Johnny

    2014-05-01

    The Norwegian Satellite Earth Observation Database for Marine and Polar Research (NORMAP) is developed for creating and maintaining a repository of Earth Observation data over the high latitude and Arctic regions to facilitate, stimulate and strengthen high quality and original multidisciplinary Earth System research, application, exploitation and education in marine, polar and climate sciences. As such it is complementing and supporting the Norwegian strategy for advancing these science disciplines in the high latitude and Arctic regions. In the international arena, NORMAP benefits and complements the EU GMES MyOcean project, and other previous GMES downstream services such as AQUAMAR, MONARCH-A, SIDARUS, etc. With the launch of the first Sentinel-1 mission NORMAP will be reinforced by the new data flow from the Copernicus Space Component. NORMAP is also acquiring data from a multitude of other satellites through the unified Copernicus system and will become one of the national thematic information services designed to benefit the environmental monitoring and support effective policy-making.

  4. Database and Registry Research in Orthopaedic Surgery: Part 2: Clinical Registry Data.

    PubMed

    Pugely, Andrew J; Martin, Christopher T; Harwood, Jared; Ong, Kevin L; Bozic, Kevin J; Callaghan, John J

    2015-11-01

    The use of large-scale national databases for observational research in orthopaedic surgery has grown substantially in the last decade, and the data sets can be categorized as either administrative claims or clinical registries. Clinical registries contain secondary data on patients with a specific diagnosis or procedure. The data are typically used for patient outcome surveillance to improve patient safety and health-care quality. Registries used in orthopaedic research exist at the regional, national, and international levels, and many were designed to specifically collect outcomes relevant to orthopaedics, such as short-term surgical complications, longer-term outcomes (implant survival or reoperations), and patient-reported outcomes. Although heterogeneous, clinical registries-in contrast to claims data-typically have a more robust list of variables, with relatively precise prospective data input, management infrastructure, and reporting systems. Some weaknesses of clinical registries include a smaller number of patients, inconstant follow-up duration, and use of sampling methods that may limit generalizability. Within the U.S., national joint registry adoption has lagged international joint registries. Given the changing health-care environment, it is likely that clinical registries will provide valuable information that has the potential to influence clinical practice improvement and health-care policy in the future. PMID:26537168

  5. A synopsis of original research projects published in scientific database in the Russian Federation.

    PubMed

    Smirnova, Daria; Pavlichenko, Alexey; Karpenko, Olga; Schmeleva, Liubov; Morozov, Petr

    2015-06-01

    The article describes the current state of scientific publications in the field of psychiatry in the Russian Federation. Issues of academic dissertations, lack of access to recent Russian language research in foreign databases, and recent reforms in the Ministry of Education and Science for overcoming these limitations are discussed in detail. Four exemplary dissertation studies published in Russian language are summarized. The first research examines the contribution of patient's verbal behavior to the reliable diagnosis of mild depression, identifying objective signs for distinguishing it from normal sadness; the mood component influenced the whole mental status and was represented in both structure and semantics of patients' speech. The second paper describes the course of panic disorder with agoraphobia, with the notable results that debut of panic disorder with full-blown panic attacks, often declines to a second accompanied with agoraphobia, which after several years gives way to limited symptom attacks and decreased agoraphobic avoidance. The third study describes the high prevalence of affective and anxiety disorders in patients with diabetes mellitus type 1 and 2, and the role of personality traits in adherence to treatment in patients with poor glucose control. The fourth project uses functional MRI for probing the features of neuronal resting-state networks in patients with temporal lobe epilepsy; the association with affective symptoms provides a model for investigating the pathophysiology of mood disorder. PMID:26022056

  6. Research and application of ORACLE performance optimizing technologies for building airplane environment resource database

    NASA Astrophysics Data System (ADS)

    Zhang, Jianjun; Sun, Jianyong; Cheng, Conggao

    2013-03-01

    Many problems exist in processing experimental aircraft vibration (temperature, humidity) data and generating the intermediate calculations during the construction of airplane environment resource database, such as the need to deal with both structural and non-structural data, weak capacity of the client browser for data processing and massive network data transferring etc. To solve the above problems, some strategies on tuning and optimization performance of database are employed base on Oracle11g, which include data storage structure tuning, the memory configuration of the server, the disk I/O tuning and SQL statement tuning. The experimental results show that the performance of airplane environment resource database is enhanced about 80% compared with the database developed in the initial demonstration and validation phase. The application of new optimization strategies to the database construction can lay a sound foundation for finishing building airplane environment resource database.

  7. The impact of the European financial crisis on clinical research within the European union or "when life gives you lemons, make lemonade"

    PubMed Central

    Tsoulfas, G

    2012-01-01

    The European Union (EU) and the world are faced with unprecedented economic challenges, which if allowed to persist could threaten its continued existence in its current form as a union. Furthermore, these same financial challenges can easily translate into societal hardship. The biomedical and pharmaceutical industries of the U.S. and Europe have been in the midst of severe financial constraints over the last few years, which will worsen in the coming years. A critical factor is a financial crisis that appears to be spreading like wildfire through Europe, with 3 of its oldest members (Greece, Ireland, Portugal) already having enlisted the aid of the International Monetary Fund (IMF) to avoid bankruptcy, and with the possibility of others to follow (Italy, Spain). Adding to this the increasing cost of introducing new medications and devices, and conducting clinical research, as well as the tightening regulatory pressures and the drying pharmaceutical pipelines, cost cutting pressures are mounting on pharmaceutical industries and the biomedical sector, whether in academia or in industry. This paper will attempt to highlight some of the problems that clinical research in Europe may be facing, as well as discuss some of the potential solutions. Although this will by no means be an exhaustive analysis, the goal is to show that times of financial hardship, such as the current one, may also provide the impetus for constructive change. PMID:23930050

  8. The impact of the European financial crisis on clinical research within the European union or "when life gives you lemons, make lemonade".

    PubMed

    Tsoulfas, G

    2012-01-01

    The European Union (EU) and the world are faced with unprecedented economic challenges, which if allowed to persist could threaten its continued existence in its current form as a union. Furthermore, these same financial challenges can easily translate into societal hardship. The biomedical and pharmaceutical industries of the U.S. and Europe have been in the midst of severe financial constraints over the last few years, which will worsen in the coming years. A critical factor is a financial crisis that appears to be spreading like wildfire through Europe, with 3 of its oldest members (Greece, Ireland, Portugal) already having enlisted the aid of the International Monetary Fund (IMF) to avoid bankruptcy, and with the possibility of others to follow (Italy, Spain). Adding to this the increasing cost of introducing new medications and devices, and conducting clinical research, as well as the tightening regulatory pressures and the drying pharmaceutical pipelines, cost cutting pressures are mounting on pharmaceutical industries and the biomedical sector, whether in academia or in industry. This paper will attempt to highlight some of the problems that clinical research in Europe may be facing, as well as discuss some of the potential solutions. Although this will by no means be an exhaustive analysis, the goal is to show that times of financial hardship, such as the current one, may also provide the impetus for constructive change. PMID:23930050

  9. The research of network database security technology based on web service

    NASA Astrophysics Data System (ADS)

    Meng, Fanxing; Wen, Xiumei; Gao, Liting; Pang, Hui; Wang, Qinglin

    2013-03-01

    Database technology is one of the most widely applied computer technologies, its security is becoming more and more important. This paper introduced the database security, network database security level, studies the security technology of the network database, analyzes emphatically sub-key encryption algorithm, applies this algorithm into the campus-one-card system successfully. The realization process of the encryption algorithm is discussed, this method is widely used as reference in many fields, particularly in management information system security and e-commerce.

  10. A study-centric database model for organizing multimodality images and metadata in animal imaging research facilities

    NASA Astrophysics Data System (ADS)

    Lee, Jasper; Gurbuz, Alparslan; Liu, Brent

    2010-03-01

    Research images and findings reports generated during imaging-based small animal imaging experiments are typically kept by imaging facilities on workstations or by investigators on burned DVD's. There usually lacks structure and organization to these data content, and are limited to directory and file names to help users find their data files. A study-centric database design is a fundamental step towards imaging systems integration and also a research data grid infrastructure for multi-institution collaborations and translational research. This paper will present a novel relational database model to maintain experimental metadata for studies, raw imaging files, post-processed images, and quantitative findings, all generated during most imaging-based animal-model studies. The integration of experimental metadata into a single database can alleviate current investigative dependency on hand-written records for current and previous experimental data. Furthermore, imaging workstations and systems that are integrated with this database can be streamlined in their data workflow with automated query services. This novel database model is being implemented in a molecular imaging data grid for evaluation with animal-model imaging studies provided from the Molecular Imaging Center at USC.

  11. The Digital Astronaut: An integrated modeling and database system for space biomedical research and operations

    NASA Astrophysics Data System (ADS)

    White, Ronald J.; McPhee, Jancy C.

    2007-02-01

    The Digital Astronaut is an integrated, modular modeling and database system that will support space biomedical research and operations in a variety of fundamental ways. This system will enable the identification and meaningful interpretation of the medical and physiological research required for human space exploration, a determination of the effectiveness of specific individual human countermeasures in reducing risk and meeting health and performance goals on challenging exploration missions and an evaluation of the appropriateness of various medical interventions during mission emergencies, accidents and illnesses. Such a computer-based, decision support system will enable the construction, validation and utilization of important predictive simulations of the responses of the whole human body to the types of stresses experienced during space flight and low-gravity environments. These simulations will be essential for direct, real-time analysis and maintenance of astronaut health and performance capabilities. The Digital Astronaut will collect and integrate past and current human data across many physiological disciplines and simulations into an operationally useful form that will not only summarize knowledge in a convenient and novel way but also reveal gaps that must be filled via new research in order to effectively ameliorate biomedical risks. Initial phases of system development will focus on simulating ground-based analog systems that are just beginning to collect multidisciplinary data in a standardized way (e.g., the International Multidisciplinary Artificial Gravity Project). During later phases, the focus will shift to development and planning for missions and to exploration mission operations. Then, the Digital Astronaut system will enable evaluation of the effectiveness of multiple, simultaneously applied countermeasures (a task made difficult by the many-system physiological effects of individual countermeasures) and allow for the prescription of individualized astronaut countermeasures. Additionally, during exploration missions, this system will support autonomous and telemedicine-assisted health and performance assessment and medical care.

  12. Triage or Tapestry? Teacher Unions' Work toward Improving Teacher Quality in an Era of Systemic Reform. A Research Report. Document R-03-1

    ERIC Educational Resources Information Center

    Bascia, Nina

    2003-01-01

    This report looks at and identifies emerging trends in the roles that teacher unions play in educational reform and improving the quality of teaching. A description of the efforts of six teacher unions to improve teacher quality within the context of the current systemic reform movement shows a range and depth of union initiatives beyond what is…

  13. Unions, Vitamins, Exercise: Unionized Graduate Students

    ERIC Educational Resources Information Center

    Dewberry, David R.

    2005-01-01

    After the turbulent labor history of America in the early to mid twentieth century, there has been a general decline of unions. Nevertheless, many graduate school teaching assistants are unionizing in attempts to gain better pay and benefits and remove themselves from an "Ivory Sweatshop." This article discusses a history of unions within graduate…

  14. The Transporter Classification Database (TCDB): recent advances

    PubMed Central

    Saier, Milton H.; Reddy, Vamsee S.; Tsu, Brian V.; Ahmed, Muhammad Saad; Li, Chun; Moreno-Hagelsieb, Gabriel

    2016-01-01

    The Transporter Classification Database (TCDB; http://www.tcdb.org) is a freely accessible reference database for transport protein research, which provides structural, functional, mechanistic, evolutionary and disease/medical information about transporters from organisms of all types. TCDB is the only transport protein classification database adopted by the International Union of Biochemistry and Molecular Biology (IUBMB). It consists of more than 10 000 non-redundant transport systems with more than 11 000 reference citations, classified into over 1000 transporter families. Transporters in TCDB can be single or multi-component systems, categorized in a functional/phylogenetic hierarchical system of classes, subclasses, families, subfamilies and transport systems. TCDB also includes updated software designed to analyze the distinctive features of transport proteins, extending its usefulness. Here we present a comprehensive update of the database contents and features and summarize recent discoveries recorded in TCDB. PMID:26546518

  15. Patterns of Undergraduates' Use of Scholarly Databases in a Large Research University

    ERIC Educational Resources Information Center

    Mbabu, Loyd Gitari; Bertram, Albert; Varnum, Ken

    2013-01-01

    Authentication data was utilized to explore undergraduate usage of subscription electronic databases. These usage patterns were linked to the information literacy curriculum of the library. The data showed that out of the 26,208 enrolled undergraduate students, 42% of them accessed a scholarly database at least once in the course of the entire…

  16. Patterns of Undergraduates' Use of Scholarly Databases in a Large Research University

    ERIC Educational Resources Information Center

    Mbabu, Loyd Gitari; Bertram, Albert; Varnum, Ken

    2013-01-01

    Authentication data was utilized to explore undergraduate usage of subscription electronic databases. These usage patterns were linked to the information literacy curriculum of the library. The data showed that out of the 26,208 enrolled undergraduate students, 42% of them accessed a scholarly database at least once in the course of the entire…

  17. CottonGen: a genomics, genetics and breeding database for cotton research

    Technology Transfer Automated Retrieval System (TEKTRAN)

    CottonGen (http://www.cottongen.org) is a curated and integrated web-based relational database providing access to publicly available genomic, genetic and breeding data for cotton. CottonGen supercedes CottonDB and the Cotton Marker Database, with enhanced tools for easier data sharing, mining, vis...

  18. The Research Potential of the Electronic OED Database at the University of Waterloo: A Case Study.

    ERIC Educational Resources Information Center

    Berg, Donna Lee

    1991-01-01

    Discusses the history and structure of the online database of the second edition of the Oxford English Dictionary (OED) and the software tools developed at the University of Waterloo to manipulate the unusually complex database. Four sample searches that indicate some types of problems that might be encountered are appended. (DB)

  19. The European Court of Justice's decision regarding the Brüstle patent and its implications for the legality of stem cell research within the European Union.

    PubMed

    Heyer, Martin; Spranger, Tade Matthias

    2013-12-01

    In 2011 the European Court of Justice issued a decision regarding the patentability of technologies derived from human embryonic stem cells. The finding will have an impact on the framework of stem cell research within the European Union and its Member States and has already triggered several political initiatives regarding the funding of research with human embryonic stem cells on the European level as well as a renewed public debate. This article will take a short look at the case history and the findings of the court. It offers some critical comments regarding the findings' consistency with European and international regulations on intellectual property rights as well as some considerations on the possible impact of the case for other fields of law. PMID:24304076

  20. Research on distributed spatial database management based on J2EE

    NASA Astrophysics Data System (ADS)

    Chen, Zhirong; Liu, Renyi; Liu, Nan

    2005-10-01

    This paper discusses how to manage the distributed multi-source isomeric database and share the information of different sources, and solves the distributed storage and retrieve of spatial data which is internet-based. By network connecting, it is realized how to manage the independent spatial database in network-wide and convert conventional c/s computing model into distributed computing model, so the problems of geo-information sharing and interoperable geo-data are successfully solved. As put forward and designed in this paper, the J2EE-based Distributed Spatial Database Management System (JDSDMS) is data-centered, and builds on the newest technology such as distributed database, WWW network and Web GIS. It is absolutely transparent of the local distributed module management, and can update the databases between different platforms through the transaction manager and distinguish various data source. The requirement of manage the distributed, multiple and isomeric city data is completed met.

  1. Inconsistencies in the red blood cell membrane proteome analysis: generation of a database for research and diagnostic applications

    PubMed Central

    Hegedűs, Tamás; Chaubey, Pururawa Mayank; Várady, György; Szabó, Edit; Sarankó, Hajnalka; Hofstetter, Lia; Roschitzki, Bernd; Sarkadi, Balázs

    2015-01-01

    Based on recent results, the determination of the easily accessible red blood cell (RBC) membrane proteins may provide new diagnostic possibilities for assessing mutations, polymorphisms or regulatory alterations in diseases. However, the analysis of the current mass spectrometry-based proteomics datasets and other major databases indicates inconsistencies—the results show large scattering and only a limited overlap for the identified RBC membrane proteins. Here, we applied membrane-specific proteomics studies in human RBC, compared these results with the data in the literature, and generated a comprehensive and expandable database using all available data sources. The integrated web database now refers to proteomic, genetic and medical databases as well, and contains an unexpected large number of validated membrane proteins previously thought to be specific for other tissues and/or related to major human diseases. Since the determination of protein expression in RBC provides a method to indicate pathological alterations, our database should facilitate the development of RBC membrane biomarker platforms and provide a unique resource to aid related further research and diagnostics. Database URL: http://rbcc.hegelab.org PMID:26078478

  2. Unraveling the Web of Viroinformatics: Computational Tools and Databases in Virus Research

    PubMed Central

    Priyadarshini, Pragya; Vrati, Sudhanshu

    2014-01-01

    The beginning of the second century of research in the field of virology (the first virus was discovered in 1898) was marked by its amalgamation with bioinformatics, resulting in the birth of a new domain—viroinformatics. The availability of more than 100 Web servers and databases embracing all or specific viruses (for example, dengue virus, influenza virus, hepatitis virus, human immunodeficiency virus [HIV], hemorrhagic fever virus [HFV], human papillomavirus [HPV], West Nile virus, etc.) as well as distinct applications (comparative/diversity analysis, viral recombination, small interfering RNA [siRNA]/short hairpin RNA [shRNA]/microRNA [miRNA] studies, RNA folding, protein-protein interaction, structural analysis, and phylotyping and genotyping) will definitely aid the development of effective drugs and vaccines. However, information about their access and utility is not available at any single source or on any single platform. Therefore, a compendium of various computational tools and resources dedicated specifically to virology is presented in this article. PMID:25428870

  3. Database management research for the Human Genome Project. Final progress report for period: 02/01/99 - 06/14/00

    SciTech Connect

    Bult, Carol J.

    1999-11-01

    The MouseBLAST server allows researchers to search a sequence within mouse/rodent sequence databases to find matching sequences that may be associated with mouse genes. Query results may be linked to gene detail records in the Mouse Genome Database (MGD). Searches are performed using WU-BLAST 2.0. All sequence databases are updated on a weekly basis.

  4. Juvenile Huntington's disease: a population-based study using the General Practice Research Database

    PubMed Central

    Douglas, Ian; Evans, Stephen; Rawlins, Michael D; Smeeth, Liam; Tabrizi, Sarah J; Wexler, Nancy S

    2013-01-01

    Background The juvenile form of Huntington's disease (HD) is a rare disorder. There are no population-based estimates of either its incidence or prevalence in any population in the world. The present study was undertaken to estimate the frequency of juvenile HD in the UK and to examine the range of pharmacological treatments used in its management. Method The records of individuals under the age of 21 who had recorded diagnoses of HD were retrieved from the General Practice Research Database from 1990 through 2010. From these data estimates of incidence and prevalence were made as well as the specific treatments used in the treatment of its physical and psychological manifestations. Results 12 incident and 21 prevalent patients with juvenile HD were identified. The 21 prevalent cases included the 12 incident cases. The minimum population-based estimate of incidence is 0.70 (95% CI 0.36 to 1.22) per million patient-years. The minimum estimate of prevalence is 6.77/million (95% CI 5.60 to 8.12) per million patient-years. Patients were most frequently prescribed antidepressants, hypnotics, antipsychotics and treatments for motor abnormalities. Conclusions In the UK, juvenile HD is an extremely rare and complex disorder. The prescribing data demonstrate that the clinical management of juvenile HD is undertaken with no formal evidence base for the efficacy or safety of the treatments used. Research into the safety and efficacy of appropriate therapies is urgently required to offset the haphazard nature of prescribing. Multinational collaboration will be necessary to enrol sufficient numbers. Exploratory studies, though, should begin now. PMID:23558730

  5. Research and writing in the history of health sciences, 1970-1982: a quantitative analysis of NLM's HISTLINE database.

    PubMed Central

    Kopp, J J

    1985-01-01

    HISTLINE, the MEDLARS file on the history of the health sciences, was analyzed to determine predominant areas of historical research and publication in the years 1970-1982, as reflected in this database produced within the History of Medicine Division at the National Library of Medicine. Subject content, chronologic and geographic breakdowns, and subjects of biographical studies are examined in view of their frequency in the file. Speculation for the predominance of particular descriptors and individuals is presented. An examination is made of the journals publishing the most medical history. Strengths and weaknesses of the database as reflected in this study also are discussed. PMID:3888330

  6. State of the Unions

    ERIC Educational Resources Information Center

    Blair, Julie

    2004-01-01

    This article discusses the corrupt leadership of two big-city teachers' unions, the Washington Teachers Union (WTU) and its Miami cousin, United Teachers of Dade (UTD), that took both unions to the brink of despair and financial ruin. While the feds were rifling through union files to build extensive criminal investigations, congress called Sandra…

  7. State of the Unions

    ERIC Educational Resources Information Center

    Blair, Julie

    2004-01-01

    This article discusses the corrupt leadership of two big-city teachers' unions, the Washington Teachers Union (WTU) and its Miami cousin, United Teachers of Dade (UTD), that took both unions to the brink of despair and financial ruin. While the feds were rifling through union files to build extensive criminal investigations, congress called Sandra…

  8. Development of USDA's expanded flavonoid database: A Tool for Epidemiological Research

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The scientific community continues to be interested in potential links between flavonoid intakes and beneficial health effects associated with certain chronic diseases such as cardiovascular diseases, some cancers and type 2 diabetes. Three separate flavonoid databases (Flavonoids (5 subclasses: fl...

  9. Substance misuse and psychiatric illness: prospective observational study using the general practice research database

    PubMed Central

    Frisher, M.; Crome, I.; Macleod, J.; Millson, D.; Croft, P.

    2005-01-01

    Objectives: To quantify the relation between substance misuse and psychiatric illness in the UK general practice population in terms of (a) the relative risk of developing one condition given prior exposure to the other and (b) the proportion of cases of one condition attributable to exposure to the other. Design: Population based prospective observational study using the general practice research database (GPRD) between 1993 and 1998. The 230 GP practices represent 3.1% of the population. Setting: England and Wales. Participants: 1.4 million registered patients of whom 3969 had both substance misuse and psychiatric diagnoses between 1993 and 1998. Main outcome measures: Relative risk (RR) for subsequent psychiatric illness among participants exposed to substance misuse and RR for subsequent substance misuse among participants exposed to psychiatric illness. Population attributable risk (PAR) of psychiatric illness attributable to substance misuse and of substance misuse attributable to psychiatric illness. Results: The baseline prevalence of psychiatric illness over the study period was 15% and 0.3% for substance abuse. RR for psychiatric illness for substance misusers compared with non-substance misusers was 1.54 (95% CI 1.47 to 1.62). RR for substance misuse among psychiatric compared with non-psychiatric cases was 2.09 (95% CI 1.99 to 2.22). PAR for psychiatric illness attributable to substance misuse was 0.2%. PAR for substance misuse attributable to psychiatric illness was 14.2%. Discussion: Only a comparatively small proportion of psychiatric illness seems possibly attributable to substance use whereas a more substantial proportion of substance use seems possibly attributable to psychiatric illness. This study does not support the hypotheses that comorbidity between substance misuse and psychiatric illness is primarily the result of substance misuse or that increasing comorbidity is largely attributable to increasing substance misuse. PMID:16166357

  10. Inconsistencies in the red blood cell membrane proteome analysis: generation of a database for research and diagnostic applications.

    PubMed

    Heged?s, Tamás; Chaubey, Pururawa Mayank; Várady, György; Szabó, Edit; Sarankó, Hajnalka; Hofstetter, Lia; Roschitzki, Bernd; Stieger, Bruno; Sarkadi, Balázs

    2015-01-01

    Based on recent results, the determination of the easily accessible red blood cell (RBC) membrane proteins may provide new diagnostic possibilities for assessing mutations, polymorphisms or regulatory alterations in diseases. However, the analysis of the current mass spectrometry-based proteomics datasets and other major databases indicates inconsistencies-the results show large scattering and only a limited overlap for the identified RBC membrane proteins. Here, we applied membrane-specific proteomics studies in human RBC, compared these results with the data in the literature, and generated a comprehensive and expandable database using all available data sources. The integrated web database now refers to proteomic, genetic and medical databases as well, and contains an unexpected large number of validated membrane proteins previously thought to be specific for other tissues and/or related to major human diseases. Since the determination of protein expression in RBC provides a method to indicate pathological alterations, our database should facilitate the development of RBC membrane biomarker platforms and provide a unique resource to aid related further research and diagnostics. PMID:26078478

  11. The Information Needs of Local Union Officials.

    ERIC Educational Resources Information Center

    Chaplan, Margaret A.; Hertenstein, Edward J.

    2002-01-01

    Discusses results of a questionnaire that was distributed to local union officials to determine their information needs and how they go about satisfying those needs. Highlights include union roles; information sources; effects of training on sources used; comparisons to previous research; suggestions for further research; and a copy of the survey…

  12. ATGC: a database of orthologous genes from closely related prokaryotic genomes and a research platform for microevolution of prokaryotes

    SciTech Connect

    Novichkov, Pavel S.; Ratnere, Igor; Wolf, Yuri I.; Koonin, Eugene V.; Dubchak, Inna

    2009-07-23

    The database of Alignable Tight Genomic Clusters (ATGCs) consists of closely related genomes of archaea and bacteria, and is a resource for research into prokaryotic microevolution. Construction of a data set with appropriate characteristics is a major hurdle for this type of studies. With the current rate of genome sequencing, it is difficult to follow the progress of the field and to determine which of the available genome sets meet the requirements of a given research project, in particular, with respect to the minimum and maximum levels of similarity between the included genomes. Additionally, extraction of specific content, such as genomic alignments or families of orthologs, from a selected set of genomes is a complicated and time-consuming process. The database addresses these problems by providing an intuitive and efficient web interface to browse precomputed ATGCs, select appropriate ones and access ATGC-derived data such as multiple alignments of orthologous proteins, matrices of pairwise intergenomic distances based on genome-wide analysis of synonymous and nonsynonymous substitution rates and others. The ATGC database will be regularly updated following new releases of the NCBI RefSeq. The database is hosted by the Genomics Division at Lawrence Berkeley National laboratory and is publicly available at http://atgc.lbl.gov.

  13. Advances in the design, development, and deployment of the U.S. Army Research Laboratory (ARL) multimodal signatures database

    NASA Astrophysics Data System (ADS)

    Bennett, Kelly; Robertson, James

    2011-06-01

    Recent advances in the design, development, and deployment of U.S. Army Research Laboratory's (ARL) Multimodal Signature Database (MMSDB) create a state-of-the-art database system with Web-based access through a Web interface designed specifically for research and development. Tens of thousands of signatures are currently available for researchers to support their algorithm development and refinement for sensors and other security systems. Each dataset is stored in (Hierarchical Data Format 5 (HDF5) format for easy modeling and storing of signatures and archived sensor data, ground truth, calibration information, algorithms, and other documentation. Archived HDF5 formatted data provides the basis for computational interoperability across a variety of tools including MATLAB, Octave, and Python. The database has a Web-based front-end with public and restricted access interfaces, along with 24/7 availability and support. This paper describes the overall design of the system, and the recent enhancements and future vision, including the ability for researchers to share algorithms, data, and documentation in the cloud, and providing an ability to run algorithms and software for testing and evaluation purposes remotely across multiple domains and computational tools. The paper will also describe in detail the HDF5 format for several multimodal sensor types.

  14. Design and utilization of a Flight Test Engineering Database Management System at the NASA Dryden Flight Research Facility

    NASA Technical Reports Server (NTRS)

    Knighton, Donna L.

    1992-01-01

    A Flight Test Engineering Database Management System (FTE DBMS) was designed and implemented at the NASA Dryden Flight Research Facility. The X-29 Forward Swept Wing Advanced Technology Demonstrator flight research program was chosen for the initial system development and implementation. The FTE DBMS greatly assisted in planning and 'mass production' card preparation for an accelerated X-29 research program. Improved Test Plan tracking and maneuver management for a high flight-rate program were proven, and flight rates of up to three flights per day, two times per week were maintained.

  15. LLNL's Regional Model Calibration and Body-Wave Discrimination Research in the Former Soviet Union using Peaceful Nuclear Explosions (PNEs)

    SciTech Connect

    Bhattacharyya, J.; Rodgers, A.; Swenson, J.; Schultz, C.; Walter, W.; Mooney, W.; Clitheroe, G.

    2000-07-14

    Long-range seismic profiles from Peaceful Nuclear Explosions (PNE) in the Former Soviet Union (FSU) provide a unique data set to investigate several important issues in regional Comprehensive Nuclear-Test-Ban Treaty (CTBT) monitoring. The recording station spacing ({approx}15 km) allows for extremely dense sampling of the propagation from the source to {approx} 3300 km. This allows us to analyze the waveforms at local, near- and far-regional and teleseismic distances. These data are used to: (1) study the evolution of regional phases and phase amplitude ratios along the profile; (2) infer one-dimensional velocity structure along the profile; and (3) evaluate the spatial correlation of regional and teleseismic travel times and regional phase amplitude ratios. We analyzed waveform data from four PNE's (m{sub b} = 5.1-5.6) recorded along profile KRATON, which is an east-west trending profile located in northern Sibertil. Short-period regional discriminants, such as P/S amplitude ratios, will be essential for seismic monitoring of the Comprehensive Nuclear-Test-Ban Treaty (CTBT) at small magnitudes (m{sub b} < 4.0). However, P/S amplitude ratios in the short-period band, 0.5-5.0 Hz, show some scatter. This scatter is primarily due to propagation and site effects, which arise from variability in the elastic and anelastic structure of the crustal waveguide. Preliminary results show that Pg and Lg propagate efficiently in north Siberia at regional distances. The amplitude ratios show some variability between adjacent stations that are modeled by simple distance trends. The effect of topography, sediment and crustal thickness, and upper mantle discontinuities on these ratios, after removal of the distance trends, will be investigated. The travel times of the body wave phases recorded on KEATON have been used to compute the one-dimensional structure of the crust and upper mantle in this region. The path-averaged one-dimensional velocity model was computed by minimizing the first arriving P-phase travel-time residuals for all distances ({Delta} = 300-2300 km). A grid search approach was used in the minimization. The most significant features of this model are the negative lid-gradient and a low-velocity zone in the upper mantle between the depths of 100-200 km; precise location of the LVZ is poorly constrained by the travel time data. We will extend our investigation to additional PNE lines to further investigate the amplitude and travel-time variations in eastern and central Eurasia. Finally, the dense station spacing of the PNE profiles allows us to model the spatial correlation of travel times and amplitude ratios through variogram modeling. The statistical analysis suggests that the correlation lengths of the travel-time and amplitude measurements are 12{sup o} and 10{sup o}, respectively.

  16. USDA-ARS Riesel Watersheds, Riesel, Texas, USA: Water quality research database

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The 75 year legacy database including discharge, sediment loss, land management, and meteorological data for the USDA-ARS Riesel Watersheds has been available on the web for more than a decade (www.ars.usda.gov/spa/hydro-data); however, only recently have additional water quality data been added. T...

  17. Heart 'omics' in AGEing (HOMAGE): design, research objectives and characteristics of the common database.

    PubMed

    Jacobs, Lotte; Thijs, Lutgarde; Jin, Yu; Zannad, Faiez; Mebazaa, Alexandre; Rouet, Philippe; Pinet, Florence; Bauters, Christophe; Pieske, Burkert; Tomaschitz, Andreas; Mamas, Mamas; Diez, Javier; McDonald, Kenneth; Cleland, John G F; Rocca, Hans-Peter Brunner-La; Heymans, Stephane; Latini, Roberto; Masson, Serge; Sever, Peter; Delles, Christian; Pocock, Stuart; Collier, Timothy; Kuznetsova, Tatiana; Staessen, Jan A

    2014-09-01

    Heart failure is common in older people and its prevalence is increasing. The Heart 'omics' in AGEing (HOMAGE) project aims to provide a biomarker approach that will improve the early diagnosis of heart failure. A large clinical database, based on (1) prospective population studies or (2) cross-sectional, prospective studies or randomized controlled trials (RCTs) of patients at risk for or with overt cardiovascular disease will be constructed to determine most promising 'omics'-based biomarkers to identify the risk of developing heart failure and/or comorbidities. Population studies, patient cohorts and RCTs are eligible for inclusion in the common database, if they received ethical approval to obtain and share data and have baseline information on cardiovascular risk factors. Currently, the HOMAGE database includes 43,065 subjects, from 20 studies in eight European countries, including healthy subjects from three population studies in France, Belgium and Italy (n  =  7,124), patients with heart failure (n  =  4,312) from four cohorts in the UK, Spain and Switzerland and patients at high risk for cardiovascular disease (n  =  31,629) in 13 cohorts. It is anticipated that more partners will join the consortium and enlarge the pooled data. This large merged database will be a useful resource with which to identify candidate biomarkers that play a role in the mechanism underlying the onset and progression of heart failure. PMID:25332706

  18. Heart ‘omics’ in AGEing (HOMAGE): design, research objectives and characteristics of the common database

    PubMed Central

    Jacobs, Lotte; Thijs, Lutgarde; Jin, Yu; Zannad, Faiez; Mebazaa, Alexandre; Rouet, Philippe; Pinet, Florence; Bauters, Christophe; Pieske, Burkert; Tomaschitz, Andreas; Mamas, Mamas; Diez, Javier; McDonald, Kenneth; Cleland, John G. F.; Rocca, Hans-Peter Brunner-La; Heymans, Stephane; Latini, Roberto; Masson, Serge; Sever, Peter; Delles, Christian; Pocock, Stuart; Collier, Timothy; Kuznetsova, Tatiana; Staessen, Jan A

    2014-01-01

    Abstract Heart failure is common in older people and its prevalence is increasing. The Heart ‘omics’ in AGEing (HOMAGE) project aims to provide a biomarker approach that will improve the early diagnosis of heart failure. A large clinical database, based on (1) prospective population studies or (2) cross-sectional, prospective studies or randomized controlled trials (RCTs) of patients at risk for or with overt cardiovascular disease will be constructed to determine most promising ‘omics’-based biomarkers to identify the risk of developing heart failure and/or comorbidities. Population studies, patient cohorts and RCTs are eligible for inclusion in the common database, if they received ethical approval to obtain and share data and have baseline information on cardiovascular risk factors. Currently, the HOMAGE database includes 43,065 subjects, from 20 studies in eight European countries, including healthy subjects from three population studies in France, Belgium and Italy (n  =  7,124), patients with heart failure (n  =  4,312) from four cohorts in the UK, Spain and Switzerland and patients at high risk for cardiovascular disease (n  =  31,629) in 13 cohorts. It is anticipated that more partners will join the consortium and enlarge the pooled data. This large merged database will be a useful resource with which to identify candidate biomarkers that play a role in the mechanism underlying the onset and progression of heart failure. PMID:25332706

  19. D Digital Model Database Applied to Conservation and Research of Wooden Construction in China

    NASA Astrophysics Data System (ADS)

    Zheng, Y.

    2013-07-01

    Protected by the Tai-Hang Mountains, Shanxi Province, located in north central China, is a highly prosperous, densely populated valley and considered to be one of the cradles of Chinese civilization. Its continuous habitation and rich culture have given rise to a large number of temple complexes and pavilions. Among these structures, 153 can be dated as early as from the Tang dynasty (618- 907C.E.) to the end of the Yuan dynasty (1279-1368C.E.) in Southern Shanxi area. The buildings are the best-preserved examples of wooden Chinese architecture in existence, exemplifying historic building technology and displaying highly intricate architectural decoration and detailing. They have survived war, earthquakes, and, in the last hundred years, neglect. In 2005, a decade-long conservation project was initiated by the State Administration of Cultural Heritage of China (SACH) to conserve and document these important buildings. The conservation process requires stabilization, conservation of important features, and, where necessary, partial dismantlement in order to replace unsound structural elements. Project team of CHCC have developed a practical recording system that created a record of all building components prior to and during the conservation process. After that we are trying to establish a comprehensive database which include all of the 153 earlier buildings, through which we can easily entering, browse, indexing information of the wooden construction, even deep into component details. The Database can help us to carry out comparative studies of these wooden structures, and, provide important support for the continued conservation of these heritage buildings. For some of the most important wooden structure, we have established three-dimensional models. Connected the Database with 3D Digital Model based on ArcGIS, we have developed 3D Digital Model Database for these cherish buildings. The 3D Digital Model Database helps us set up an integrate information inventory for wooden structure with their similar types in China, and; makes it much easier to carry out survey of these structures at any stage for the purpose of structure monitor. Large amounts of data in the wooden structure can be intuitively expressed graphically to show its spatial distribution; and we can make comprehensive assessment of the component group by observe the spatial pattern, or evaluate the whole building damage through the database. The most interesting is that, with the development of mobile terminal equipment, the 3D Digital Model Database of Wooden Structure can be displayed in virtual exhibition easily via the internet by them.

  20. A plant resource and experiment management system based on the Golm Plant Database as a basic tool for omics research

    PubMed Central

    Köhl, Karin I; Basler, Georg; Lüdemann, Alexander; Selbig, Joachim; Walther, Dirk

    2008-01-01

    Background For omics experiments, detailed characterisation of experimental material with respect to its genetic features, its cultivation history and its treatment history is a requirement for analyses by bioinformatics tools and for publication needs. Furthermore, meta-analysis of several experiments in systems biology based approaches make it necessary to store this information in a standardised manner, preferentially in relational databases. In the Golm Plant Database System, we devised a data management system based on a classical Laboratory Information Management System combined with web-based user interfaces for data entry and retrieval to collect this information in an academic environment. Results The database system contains modules representing the genetic features of the germplasm, the experimental conditions and the sampling details. In the germplasm module, genetically identical lines of biological material are generated by defined workflows, starting with the import workflow, followed by further workflows like genetic modification (transformation), vegetative or sexual reproduction. The latter workflows link lines and thus create pedigrees. For experiments, plant objects are generated from plant lines and united in so-called cultures, to which the cultivation conditions are linked. Materials and methods for each cultivation step are stored in a separate ACCESS database of the plant cultivation unit. For all cultures and thus every plant object, each cultivation site and the culture's arrival time at a site are logged by a barcode-scanner based system. Thus, for each plant object, all site-related parameters, e.g. automatically logged climate data, are available. These life history data and genetic information for the plant objects are linked to analytical results by the sampling module, which links sample components to plant object identifiers. This workflow uses controlled vocabulary for organs and treatments. Unique names generated by the system and barcode labels facilitate identification and management of the material. Web pages are provided as user interfaces to facilitate maintaining the system in an environment with many desktop computers and a rapidly changing user community. Web based search tools are the basis for joint use of the material by all researchers of the institute. Conclusion The Golm Plant Database system, which is based on a relational database, collects the genetic and environmental information on plant material during its production or experimental use at the Max-Planck-Institute of Molecular Plant Physiology. It thus provides information according to the MIAME standard for the component 'Sample' in a highly standardised format. The Plant Database system thus facilitates collaborative work and allows efficient queries in data analysis for systems biology research. PMID:18495032

  1. In Quest of a Gender-Inclusive Theory of Leadership: Contributions from Research on Women Leaders in School Unions.

    ERIC Educational Resources Information Center

    Intriligator, Barbara A.

    Current research on women leaders has concentrated on four themes, all of which have been treated in terms of male-oriented leadership theory. Some studies have concentrated on social and psychological differences between men and women leaders, while a second group notes workplace attitudes toward stereotyped male and female traits. Both of these…

  2. The MYCOGLOBE Project: A European Union Funded Successful Experiment in Enhancing Cooperation and Coordination Amongst Mycotoxin Researchers Worldwide

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In 2004, the European Commission approved the specific support action “Integration of Mycotoxin and Toxigenic Fungi Research for Food Safety in the Global System” (MycoGlobe, contract FOOD-CT-2004-007174) within the Sixth Framework Programme, Food Quality and Safety. The aim of the MycoGlobe projec...

  3. International Nuclear Safety Center (INSC) database

    SciTech Connect

    Sofu, T.; Ley, H.; Turski, R.B.

    1997-08-01

    As an integral part of DOE`s International Nuclear Safety Center (INSC) at Argonne National Laboratory, the INSC Database has been established to provide an interactively accessible information resource for the world`s nuclear facilities and to promote free and open exchange of nuclear safety information among nations. The INSC Database is a comprehensive resource database aimed at a scope and level of detail suitable for safety analysis and risk evaluation for the world`s nuclear power plants and facilities. It also provides an electronic forum for international collaborative safety research for the Department of Energy and its international partners. The database is intended to provide plant design information, material properties, computational tools, and results of safety analysis. Initial emphasis in data gathering is given to Soviet-designed reactors in Russia, the former Soviet Union, and Eastern Europe. The implementation is performed under the Oracle database management system, and the World Wide Web is used to serve as the access path for remote users. An interface between the Oracle database and the Web server is established through a custom designed Web-Oracle gateway which is used mainly to perform queries on the stored data in the database tables.

  4. Validity of registration of ICD codes and prescriptions in a research database in Swedish primary care: a cross-sectional study in Skaraborg primary care database

    PubMed Central

    2010-01-01

    Background In recent years, several primary care databases recording information from computerized medical records have been established and used for quality assessment of medical care and research. However, to be useful for research purposes, the data generated routinely from every day practice require registration of high quality. In this study we aimed to investigate (i) the frequency and validity of ICD code and drug prescription registration in the new Skaraborg primary care database (SPCD) and (ii) to investigate the sources of variation in this registration. Methods SPCD contains anonymous electronic medical records (ProfDoc III) automatically retrieved from all 24 public health care centres (HCC) in Skaraborg, Sweden. The frequencies of ICD code registration for the selected diagnoses diabetes mellitus, hypertension and chronic cardiovascular disease and the relevant drug prescriptions in the time period between May 2002 and October 2003 were analysed. The validity of data registration in the SPCD was assessed in a random sample of 50 medical records from each HCC (n = 1200 records) using the medical record text as gold standard. The variance of ICD code registration was studied with multi-level logistic regression analysis and expressed as median odds ratio (MOR). Results For diabetes mellitus and hypertension ICD codes were registered in 80-90% of cases, while for congestive heart failure and ischemic heart disease ICD codes were registered more seldom (60-70%). Drug prescription registration was overall high (88%). A correlation between the frequency of ICD coded visits and the sensitivity of the ICD code registration was found for hypertension and congestive heart failure but not for diabetes or ischemic heart disease. The frequency of ICD code registration varied from 42 to 90% between HCCs, and the greatest variation was found at the physician level (MORPHYSICIAN = 4.2 and MORHCC = 2.3). Conclusions Since the frequency of ICD code registration varies between different diagnoses, each diagnosis must be separately validated. Improved frequency and quality of ICD code registration might be achieved by interventions directed towards the physicians where the greatest amount of variation was found. PMID:20416069

  5. Search Middleware and the Simple Digital Library Interoperability Protocol [and] Meeting the Challenge of Film Research In the Electronic Age [and] Collection-based Persistent Digital Archives-Part 1 [and] The Virtual Union Catalog: A Comparative Study.

    ERIC Educational Resources Information Center

    Paepcke, Andreas; Brandriff, Robert; Janee, Greg; Larson, Ray; Ludaescher, Bertram; Melnik, Sergey; Raghavan, Sriram; [and] Owen, Catherine; Pearson, Tony; Arnold, Stephen; [and] Moore, Reagan; Baru, Chaitan; Rajasekar, Arcot; Ludaescher, Bertram; Marciano, Richard; Wan, Michael; Schroeder, Wayne; Gupta, Amarnath; [and] Coyle, Karen

    2000-01-01

    Includes four articles that discuss: (1) search middleware, or software packages that allow access to information sources for digital libraries; (2) film archives and building online collections of data for use in film research and teaching; (3) digital archives; and (4) a virtual union catalog for the University of California. (LRW)

  6. Adolescent Violent Victimization and Precocious Union Formation.

    PubMed

    C Kuhl, Danielle; Warner, David F; Wilczak, Andrew

    2012-11-01

    This article bridges scholarship in criminology and family sociology by extending arguments about "precocious exits" from adolescence to consider early union formation as a salient outcome of violent victimization for youths. Research indicates that early union formation is associated with several negative outcomes; yet the absence of attention to union formation as a consequence of violent victimization is noteworthy. We address this gap by drawing on life course theory and data from the National Longitudinal Study of Adolescent Health (Add Health) to examine the effect of violent victimization ("street" violence) on the timing of first co-residential union formation-differentiating between marriage and cohabitation-in young adulthood. Estimates from Cox proportional hazard models show that adolescent victims of street violence experience higher rates of first union formation, especially marriage, early in the transition to adulthood; however, this effect declines with age, as such unions become more normative. Importantly, the effect of violent victimization on first union timing is robust to controls for nonviolent delinquency, substance abuse, and violent perpetration. We conclude by discussing directions for future research on the association between violent victimization and coresidential unions with an eye toward the implications of such early union formation for desistance. PMID:24431471

  7. What can we learn from a decade of database audits? The Duke Clinical Research Institute experience, 1997–2006

    PubMed Central

    Rostami, Reza; Nahm, Meredith; Pieper, Carl F.

    2011-01-01

    Background Despite a pressing and well-documented need for better sharing of information on clinical trials data quality assurance methods, many research organizations remain reluctant to publish descriptions of and results from their internal auditing and quality assessment methods. Purpose We present findings from a review of a decade of internal data quality audits performed at the Duke Clinical Research Institute, a large academic research organization that conducts data management for a diverse array of clinical studies, both academic and industry-sponsored. In so doing, we hope to stimulate discussions that could benefit the wider clinical research enterprise by providing insight into methods of optimizing data collection and cleaning, ultimately helping patients and furthering essential research. Methods We present our audit methodologies, including sampling methods, audit logistics, sample sizes, counting rules used for error rate calculations, and characteristics of audited trials. We also present database error rates as computed according to two analytical methods, which we address in detail, and discuss the advantages and drawbacks of two auditing methods used during this ten-year period. Results Our review of the DCRI audit program indicates that higher data quality may be achieved from a series of small audits throughout the trial rather than through a single large database audit at database lock. We found that error rates trended upward from year to year in the period characterized by traditional audits performed at database lock (1997–2000), but consistently trended downward after periodic statistical process control type audits were instituted (2001–2006). These increases in data quality were also associated with cost savings in auditing, estimated at 1000 hours per year, or the efforts of one-half of a full time equivalent (FTE). Limitations Our findings are drawn from retrospective analyses and are not the result of controlled experiments, and may therefore be subject to unanticipated confounding. In addition, the scope and type of audits we examine here are specific to our institution, and our results may not be broadly generalizable. Conclusions Use of statistical process control methodologies may afford advantages over more traditional auditing methods, and further research will be necessary to confirm the reliability and usability of such techniques. We believe that open and candid discussion of data quality assurance issues among academic and clinical research organizations will ultimately benefit the entire research community in the coming era of increased data sharing and re-use. PMID:19342467

  8. A Hypervelocity Experimental Research Database (HERD): Support for the Wright Laboratory Armament Directorate Code Validation Program (COVAL)

    SciTech Connect

    Mullin, S.A.; Anderson, C.E. Jr.; Hertel, E.S. Jr.; Hunt, R.D.

    1994-10-01

    The Hypervelocity Experimental Research Database (HERD) described in this paper was developed to aid researchers with code validation for impacts that occur at velocities faster than the testable regime. Codes of concern include both hydrocodes and fast-running analytical or semi-empirical models used to predict the impact phenomenology and damage that results to projectiles and targets. There are several well documented experimental programs that can serve as benchmarks for code validation; these are identified and described. Recommendations for further experimentation (a canonical problem) to provide validation data are also discussed.

  9. Creation and use of a database in clinical and translational research.

    PubMed

    Smith, Janet P; Elliott, Alan C; Hynan, Linda S; Reisch, Joan S; Waddell, Stan A

    2010-03-01

    Often data collection for clinical studies is an afterthought. The results of such an approach are incomplete or confusing data that can, as a worst case, result in scrapping and restarting the entire study. We discuss the planning process for data collection and storage to include encounter form development; data flow and capture; data checking, verification, and validation; advantage of relational databases over spreadsheets; data security; and aspects of a complete data system. PMID:20009953

  10. Unions on the Margin?

    ERIC Educational Resources Information Center

    Marchington, Mick

    1990-01-01

    Longitudinal case studies of four British organizations tested theories that union membership is waning, collective bargaining is being separated from strategic decision making, and employee involvement is lessening union impact. The conclusion reached was that the marginalization of unions has more complex causes; employee relations need to be…

  11. Unions Play Politics.

    ERIC Educational Resources Information Center

    Bridgman, Anne

    1991-01-01

    The nation's two teacher unions' lobbying and political action efforts have been the subject of considerable criticism. In addition to the federal level, state and local union political action committees exist. Reviews the agency-shop issue, and estimates union dues paid and how they are spent. (MLF)

  12. Databases and Geographical Information Systems at the research/teaching interface: palaeoclimate proxies, freshwater biodiversity and the OMEGA project

    NASA Astrophysics Data System (ADS)

    Horne, David

    2013-04-01

    The Mutual Ostracod Temperature Range (MOTR) method provides Quaternary palaeotemperature range estimates based on fossil ostracod assemblages calibrated using modern distributional databases and climate data. Over the past five years, aspects of the development and application of the MOTR method have been incorporated into undergraduate teaching in two second-year modules (Global Environmental Change and Digital Worlds: Cartography, Geographical Information Systems and Modelling) via lectures and practical exercises. Consequently, several students became sufficiently interested and enthused to undertake successful major projects aimed at developing, testing and applying aspects of the method, leading in turn to postgraduate work on the same topic in two cases and in a third case to co-authorship of a research publication. Thus both research and teaching have benefited from the integration of an innovative geoscience application with undergraduate coursework. The scope of MOTR applications is being expanded from European to global via the Ostracod Metadatabase of Environmental and Geographical Attributes (OMEGA) project; the current focus is on harmonising North American and European datasets, supported by the EU-funded (FP7) BioFresh project which is building a global information platform with access to all available databases of freshwater biodiversity. Undergraduate participation will be sought to underpin a Citizen Science initiative aimed at checking, correcting and validating the geographic referencing of species' records in the databases, using datasets exported as Keyhole Markup Language files for use in Google Earth.

  13. Development of prostate cancer research database with the clinical data warehouse technology for direct linkage with electronic medical record system

    PubMed Central

    Choi, In Young; Park, Seungho; Park, Bumjoon; Chung, Byung Ha; Kim, Choung-Soo; Lee, Hyun Moo; Byun, Seok-Soo; Lee, Ji Youl

    2013-01-01

    Purpose: In spite of increased prostate cancer patients, little is known about the impact of treatments for prostate cancer patients and outcome of different treatments based on nationwide data. In order to obtain more comprehensive information for Korean prostate cancer patients, many professionals urged to have national system to monitor the quality of prostate cancer care. To gain its objective, the prostate cancer database system was planned and cautiously accommodated different views from various professions. Methods: This prostate cancer research database system incorporates information about a prostate cancer research including demographics, medical history, operation information, laboratory, and quality of life surveys. And, this system includes three different ways of clinical data collection to produce a comprehensive data base; direct data extraction from electronic medical record (EMR) system, manual data entry after linking EMR documents like magnetic resonance imaging findings and paper-based data collection for survey from patients. Results: We implemented clinical data warehouse technology to test direct EMR link method with St. Mary’s Hospital system. Using this method, total number of eligible patients were 2,300 from 1997 until 2012. Among them, 538 patients conducted surgery and others have different treatments. Conclusions: Our database system could provide the infrastructure for collecting error free data to support various retrospective and prospective studies. PMID:24223403

  14. CicArVarDB: SNP and InDel database for advancing genetics research and breeding applications in chickpea

    PubMed Central

    Doddamani, Dadakhalandar; Khan, Aamir W.; Katta, Mohan A. V. S. K; Agarwal, Gaurav; Thudi, Mahendar; Ruperao, Pradeep; Edwards, David; Varshney, Rajeev K.

    2015-01-01

    Molecular markers are valuable tools for breeders to help accelerate crop improvement. High throughput sequencing technologies facilitate the discovery of large-scale variations such as single nucleotide polymorphisms (SNPs) and simple sequence repeats (SSRs). Sequencing of chickpea genome along with re-sequencing of several chickpea lines has enabled the discovery of 4.4 million variations including SNPs and InDels. Here we report a repository of 1.9 million variations (SNPs and InDels) anchored on eight pseudomolecules in a custom database, referred as CicArVarDB that can be accessed at http://cicarvardb.icrisat.org/. It includes an easy interface for users to select variations around specific regions associated with quantitative trait loci, with embedded webBLAST search and JBrowse visualisation. We hope that this database will be immensely useful for the chickpea research community for both advancing genetics research as well as breeding applications for crop improvement. Database URL: http://cicarvardb.icrisat.org. PMID:26289427

  15. CicArVarDB: SNP and InDel database for advancing genetics research and breeding applications in chickpea.

    PubMed

    Doddamani, Dadakhalandar; Khan, Aamir W; Katta, Mohan A V S K; Agarwal, Gaurav; Thudi, Mahendar; Ruperao, Pradeep; Edwards, David; Varshney, Rajeev K

    2015-01-01

    Molecular markers are valuable tools for breeders to help accelerate crop improvement. High throughput sequencing technologies facilitate the discovery of large-scale variations such as single nucleotide polymorphisms (SNPs) and simple sequence repeats (SSRs). Sequencing of chickpea genome along with re-sequencing of several chickpea lines has enabled the discovery of 4.4 million variations including SNPs and InDels. Here we report a repository of 1.9 million variations (SNPs and InDels) anchored on eight pseudomolecules in a custom database, referred as CicArVarDB that can be accessed at http://cicarvardb.icrisat.org/. It includes an easy interface for users to select variations around specific regions associated with quantitative trait loci, with embedded webBLAST search and JBrowse visualisation. We hope that this database will be immensely useful for the chickpea research community for both advancing genetics research as well as breeding applications for crop improvement. Database URL: http://cicarvardb.icrisat.org. PMID:26289427

  16. The Evolution of Legislation in the Field of Medically Assisted Reproduction and Embryo Stem Cell Research in European Union Members

    PubMed Central

    Busardò, Francesco Paolo; Napoletano, Simona; Zaami, Simona; Frati, Paola

    2014-01-01

    Medically Assisted Reproduction (MAR), involving in vitro fertilisation (IVF), and research on embryos have created expectation to many people affected by infertility; at the same time it has generated a surplus of laws and ethical and social debates. Undoubtedly, MAR represents a rather new medical field and constant developments in medicine and new opportunities continue to defy the attempt to respond to those questions. In this paper, the authors reviewed the current legislation in the 28 EU member states trying to evaluate the different legislation paths adopted over the last 15 years and highlighting those EU countries with no specific legislation in place and MAR is covered by a general health Law and those countries in which there are no laws in this field but only “guidelines.” The second aim of this work has been to compare MAR legislation and embryo research in EU countries, which derive from different origins ranging from an extremely prohibitive approach versus a liberal one, going through a cautious regulatory approach. PMID:25147794

  17. Food Service and the College Union. College Unions at Work.

    ERIC Educational Resources Information Center

    Osterheld, Douglas C.

    This publication, one in a series of monographs on college unions, explores the importance, role, and function of food services in the college union. Major topics discussed include: (1) food service and the college union, (2) union food service and the campus, (3) union food service and the community, (4) organization of union food services, (5)…

  18. Designing and recruiting to UK autism spectrum disorder research databases: do they include representative children with valid ASD diagnoses?

    PubMed Central

    Warnell, F; George, B; McConachie, H; Johnson, M; Hardy, R; Parr, J R

    2015-01-01

    Objectives (1) Describe how the Autism Spectrum Database-UK (ASD-UK) was established; (2) investigate the representativeness of the first 1000 children and families who participated, compared to those who chose not to; (3) investigate the reliability of the parent-reported Autism Spectrum Disorder (ASD) diagnoses, and present evidence about the validity of diagnoses, that is, whether children recruited actually have an ASD; (4) present evidence about the representativeness of the ASD-UK children and families, by comparing their characteristics with the first 1000 children and families from the regional Database of children with ASD living in the North East (Daslne), and children and families identified from epidemiological studies. Setting Recruitment through a network of 50 UK child health teams and self-referral. Patients Parents/carers with a child with ASD, aged 2–16 years, completed questionnaires about ASD and some gave professionals’ reports about their children. Results 1000 families registered with ASD-UK in 30 months. Children of families who participated, and of the 208 who chose not to, were found to be very similar on: gender ratio, year of birth, ASD diagnosis and social deprivation score. The reliability of parent-reported ASD diagnoses of children was very high when compared with clinical reports (over 96%); no database child without ASD was identified. A comparison of gender, ASD diagnosis, age at diagnosis, school placement, learning disability, and deprivation score of children and families from ASD-UK with 1084 children and families from Daslne, and families from population studies, showed that ASD-UK families are representative of families of children with ASD overall. Conclusions ASD-UK includes families providing parent-reported data about their child and family, who appear to be broadly representative of UK children with ASD. Families continue to join the databases and more than 3000 families can now be contacted by researchers about UK autism research. PMID:26341584

  19. Construction of a rice glycoside hydrolase phylogenomic database and identification of targets for biofuel research

    PubMed Central

    Sharma, Rita; Cao, Peijian; Jung, Ki-Hong; Sharma, Manoj K.; Ronald, Pamela C.

    2013-01-01

    Glycoside hydrolases (GH) catalyze the hydrolysis of glycosidic bonds in cell wall polymers and can have major effects on cell wall architecture. Taking advantage of the massive datasets available in public databases, we have constructed a rice phylogenomic database of GHs (http://ricephylogenomics.ucdavis.edu/cellwalls/gh/). This database integrates multiple data types including the structural features, orthologous relationships, mutant availability, and gene expression patterns for each GH family in a phylogenomic context. The rice genome encodes 437 GH genes classified into 34 families. Based on pairwise comparison with eight dicot and four monocot genomes, we identified 138 GH genes that are highly diverged between monocots and dicots, 57 of which have diverged further in rice as compared with four monocot genomes scanned in this study. Chromosomal localization and expression analysis suggest a role for both whole-genome and localized gene duplications in expansion and diversification of GH families in rice. We examined the meta-profiles of expression patterns of GH genes in twenty different anatomical tissues of rice. Transcripts of 51 genes exhibit tissue or developmental stage-preferential expression, whereas, seventeen other genes preferentially accumulate in actively growing tissues. When queried in RiceNet, a probabilistic functional gene network that facilitates functional gene predictions, nine out of seventeen genes form a regulatory network with the well-characterized genes involved in biosynthesis of cell wall polymers including cellulose synthase and cellulose synthase-like genes of rice. Two-thirds of the GH genes in rice are up regulated in response to biotic and abiotic stress treatments indicating a role in stress adaptation. Our analyses identify potential GH targets for cell wall modification. PMID:23986771

  20. Databases: Beyond the Basics.

    ERIC Educational Resources Information Center

    Whittaker, Robert

    This presented paper offers an elementary description of database characteristics and then provides a survey of databases that may be useful to the teacher and researcher in Slavic and East European languages and literatures. The survey focuses on commercial databases that are available, usable, and needed. Individual databases discussed include:…

  1. Experiment Databases

    NASA Astrophysics Data System (ADS)

    Vanschoren, Joaquin; Blockeel, Hendrik

    Next to running machine learning algorithms based on inductive queries, much can be learned by immediately querying the combined results of many prior studies. Indeed, all around the globe, thousands of machine learning experiments are being executed on a daily basis, generating a constant stream of empirical information on machine learning techniques. While the information contained in these experiments might have many uses beyond their original intent, results are typically described very concisely in papers and discarded afterwards. If we properly store and organize these results in central databases, they can be immediately reused for further analysis, thus boosting future research. In this chapter, we propose the use of experiment databases: databases designed to collect all the necessary details of these experiments, and to intelligently organize them in online repositories to enable fast and thorough analysis of a myriad of collected results. They constitute an additional, queriable source of empirical meta-data based on principled descriptions of algorithm executions, without reimplementing the algorithms in an inductive database. As such, they engender a very dynamic, collaborative approach to experimentation, in which experiments can be freely shared, linked together, and immediately reused by researchers all over the world. They can be set up for personal use, to share results within a lab or to create open, community-wide repositories. Here, we provide a high-level overview of their design, and use an existing experiment database to answer various interesting research questions about machine learning algorithms and to verify a number of recent studies.

  2. PGSB PlantsDB: updates to the database framework for comparative plant genome research.

    PubMed

    Spannagl, Manuel; Nussbaumer, Thomas; Bader, Kai C; Martis, Mihaela M; Seidel, Michael; Kugler, Karl G; Gundlach, Heidrun; Mayer, Klaus F X

    2016-01-01

    PGSB (Plant Genome and Systems Biology: formerly MIPS) PlantsDB (http://pgsb.helmholtz-muenchen.de/plant/index.jsp) is a database framework for the comparative analysis and visualization of plant genome data. The resource has been updated with new data sets and types as well as specialized tools and interfaces to address user demands for intuitive access to complex plant genome data. In its latest incarnation, we have re-worked both the layout and navigation structure and implemented new keyword search options and a new BLAST sequence search functionality. Actively involved in corresponding sequencing consortia, PlantsDB has dedicated special efforts to the integration and visualization of complex triticeae genome data, especially for barley, wheat and rye. We enhanced CrowsNest, a tool to visualize syntenic relationships between genomes, with data from the wheat sub-genome progenitor Aegilops tauschii and added functionality to the PGSB RNASeqExpressionBrowser. GenomeZipper results were integrated for the genomes of barley, rye, wheat and perennial ryegrass and interactive access is granted through PlantsDB interfaces. Data exchange and cross-linking between PlantsDB and other plant genome databases is stimulated by the transPLANT project (http://transplantdb.eu/). PMID:26527721

  3. PGSB PlantsDB: updates to the database framework for comparative plant genome research

    PubMed Central

    Spannagl, Manuel; Nussbaumer, Thomas; Bader, Kai C.; Martis, Mihaela M.; Seidel, Michael; Kugler, Karl G.; Gundlach, Heidrun; Mayer, Klaus F.X.

    2016-01-01

    PGSB (Plant Genome and Systems Biology: formerly MIPS) PlantsDB (http://pgsb.helmholtz-muenchen.de/plant/index.jsp) is a database framework for the comparative analysis and visualization of plant genome data. The resource has been updated with new data sets and types as well as specialized tools and interfaces to address user demands for intuitive access to complex plant genome data. In its latest incarnation, we have re-worked both the layout and navigation structure and implemented new keyword search options and a new BLAST sequence search functionality. Actively involved in corresponding sequencing consortia, PlantsDB has dedicated special efforts to the integration and visualization of complex triticeae genome data, especially for barley, wheat and rye. We enhanced CrowsNest, a tool to visualize syntenic relationships between genomes, with data from the wheat sub-genome progenitor Aegilops tauschii and added functionality to the PGSB RNASeqExpressionBrowser. GenomeZipper results were integrated for the genomes of barley, rye, wheat and perennial ryegrass and interactive access is granted through PlantsDB interfaces. Data exchange and cross-linking between PlantsDB and other plant genome databases is stimulated by the transPLANT project (http://transplantdb.eu/). PMID:26527721

  4. The importance of total genome databases in research on Akoya pearl oyster.

    PubMed

    Watabe, Shugo

    2013-10-01

    Pearl is the most valuable form of gem made by organisms and its beauty has been considered attractive and precious by people all over the world. Pearl oyster aquaculture system, in which a graft from the mantle pallium is transplanted with a nucleus into mother pearl oysters, is currently conducted at the industrial level. However, it is unclear what molecular mechanisms are involved in this system of pearl formation, which produces brilliant and beautiful nacreous layers. Since it takes long time to look for the proteins and genes possibly participating in the molluskan shell formation, another sophisticated strategy has been expected to screen candidate genes. One breakthrough in the latter area was the development of next-generation sequencing (NGS) in place of the automated Sanger method, the first generation sequencing technique. Using NGS, expressed sequence tag (EST) libraries were constructed from pallial mantle and pearl sac, which form the nacreous layer, and from the mantle edge, which forms the prismatic layer in the Akoya pearl oyster Pinctada fucata. Subsequently, the total genome sequence of the Akoya pearl oyster was analyzed. This database, together with the EST database mentioned above, is useful for identifying genes responsible for superior phenotype characters for pearl oyster aquaculture such as fast growth, disease resistance, easy domestication, and ability to produce high quality pearls. Subsequent marker-assisted breeding of the Akoya pearl oyster should establish strains with superior genotypes, producing even higher quality Akoya pearls. PMID:24125641

  5. The Energy Science and Technology Database on a local library system: A case study at the Los Alamos National Research Library

    SciTech Connect

    Holtkamp, I.S.

    1994-10-01

    This paper presents an overview of efforts at Los Alamos National Laboratory to acquire and mount the Energy Science and Technology Database (EDB) as a citation database on the Research Library`s Geac Advance system. The rationale for undertaking this project and expected benefits are explained. Significant issues explored are loading non-USMARC records into a MARC-based library system, the use of EDB records to replace or supplement in-house cataloging of technical reports, the impact of different cataloging standards and database size on searching and retrieval, and how integrating an external database into the library`s online catalog may affect staffing and workflow.

  6. Challenges of molecular nutrition research 6: the nutritional phenotype database to store, share and evaluate nutritional systems biology studies

    PubMed Central

    Bouwman, Jildau; Dragsted, Lars O.; Drevon, Christian A.; Elliott, Ruan; de Groot, Philip; Kaput, Jim; Mathers, John C.; Müller, Michael; Pepping, Fre; Saito, Jahn; Scalbert, Augustin; Radonjic, Marijana; Rocca-Serra, Philippe; Travis, Anthony; Wopereis, Suzan; Evelo, Chris T.

    2010-01-01

    The challenge of modern nutrition and health research is to identify food-based strategies promoting life-long optimal health and well-being. This research is complex because it exploits a multitude of bioactive compounds acting on an extensive network of interacting processes. Whereas nutrition research can profit enormously from the revolution in ‘omics’ technologies, it has discipline-specific requirements for analytical and bioinformatic procedures. In addition to measurements of the parameters of interest (measures of health), extensive description of the subjects of study and foods or diets consumed is central for describing the nutritional phenotype. We propose and pursue an infrastructural activity of constructing the “Nutritional Phenotype database” (dbNP). When fully developed, dbNP will be a research and collaboration tool and a publicly available data and knowledge repository. Creation and implementation of the dbNP will maximize benefits to the research community by enabling integration and interrogation of data from multiple studies, from different research groups, different countries and different—omics levels. The dbNP is designed to facilitate storage of biologically relevant, pre-processed—omics data, as well as study descriptive and study participant phenotype data. It is also important to enable the combination of this information at different levels (e.g. to facilitate linkage of data describing participant phenotype, genotype and food intake with information on study design and—omics measurements, and to combine all of this with existing knowledge). The biological information stored in the database (i.e. genetics, transcriptomics, proteomics, biomarkers, metabolomics, functional assays, food intake and food composition) is tailored to nutrition research and embedded in an environment of standard procedures and protocols, annotations, modular data-basing, networking and integrated bioinformatics. The dbNP is an evolving enterprise, which is only sustainable if it is accepted and adopted by the wider nutrition and health research community as an open source, pre-competitive and publicly available resource where many partners both can contribute and profit from its developments. We introduce the Nutrigenomics Organisation (NuGO, http://www.nugo.org) as a membership association responsible for establishing and curating the dbNP. Within NuGO, all efforts related to dbNP (i.e. usage, coordination, integration, facilitation and maintenance) will be directed towards a sustainable and federated infrastructure. PMID:21052526

  7. YM500v2: a small RNA sequencing (smRNA-seq) database for human cancer miRNome research.

    PubMed

    Cheng, Wei-Chung; Chung, I-Fang; Tsai, Cheng-Fong; Huang, Tse-Shun; Chen, Chen-Yang; Wang, Shao-Chuan; Chang, Ting-Yu; Sun, Hsing-Jen; Chao, Jeffrey Yung-Chuan; Cheng, Cheng-Chung; Wu, Cheng-Wen; Wang, Hsei-Wei

    2015-01-01

    We previously presented YM500, which is an integrated database for miRNA quantification, isomiR identification, arm switching discovery and novel miRNA prediction from 468 human smRNA-seq datasets. Here in this updated YM500v2 database (http://ngs.ym.edu.tw/ym500/), we focus on the cancer miRNome to make the database more disease-orientated. New miRNA-related algorithms developed after YM500 were included in YM500v2, and, more significantly, more than 8000 cancer-related smRNA-seq datasets (including those of primary tumors, paired normal tissues, PBMC, recurrent tumors, and metastatic tumors) were incorporated into YM500v2. Novel miRNAs (miRNAs not included in the miRBase R21) were not only predicted by three independent algorithms but also cleaned by a new in silico filtration strategy and validated by wetlab data such as Cross-Linked ImmunoPrecipitation sequencing (CLIP-seq) to reduce the false-positive rate. A new function 'Meta-analysis' is additionally provided for allowing users to identify real-time differentially expressed miRNAs and arm-switching events according to customer-defined sample groups and dozens of clinical criteria tidying up by proficient clinicians. Cancer miRNAs identified hold the potential for both basic research and biotech applications. PMID:25398902

  8. Research Update: Highlights from the Out-of-School Time Database. Number 3

    ERIC Educational Resources Information Center

    Harris, Erin

    2008-01-01

    This "Research Update" explores two major themes: (1) Using evaluation to shape program improvement and planning; and (2) Out-of-school time benefits to older youth and their families. Themes were culled from 13 research and evaluation reports added to the Out-of-School Time (OST) Program Research and Evaluation Bibliography in September 2008.…

  9. A spatial classification and database for management, research, and policy making: The Great Lakes aquatic habitat framework

    USGS Publications Warehouse

    Wang, Lizhu; Riseng, Catherine M.; Mason, Lacey; Werhrly, Kevin; Rutherford, Edward; McKenna Jr, James E.; Castiglione, Chris; Johnson, Lucinda B.; Infante, Dana M.; Sowa, Scott P.; Robertson, Mike; Schaeffer, Jeff; Khoury, Mary; Gaiot, John; Hollenhurst, Tom; Brooks, Colin N.; Coscarelli, Mark

    2015-01-01

    Managing the world's largest and most complex freshwater ecosystem, the Laurentian Great Lakes, requires a spatially hierarchical basin-wide database of ecological and socioeconomic information that is comparable across the region. To meet such a need, we developed a spatial classification framework and database — Great Lakes Aquatic Habitat Framework (GLAHF). GLAHF consists of catchments, coastal terrestrial, coastal margin, nearshore, and offshore zones that encompass the entire Great Lakes Basin. The catchments captured in the database as river pour points or coastline segments are attributed with data known to influence physicochemical and biological characteristics of the lakes from the catchments. The coastal terrestrial zone consists of 30-m grid cells attributed with data from the terrestrial region that has direct connection with the lakes. The coastal margin and nearshore zones consist of 30-m grid cells attributed with data describing the coastline conditions, coastal human disturbances, and moderately to highly variable physicochemical and biological characteristics. The offshore zone consists of 1.8-km grid cells attributed with data that are spatially less variable compared with the other aquatic zones. These spatial classification zones and their associated data are nested within lake sub-basins and political boundaries and allow the synthesis of information from grid cells to classification zones, within and among political boundaries, lake sub-basins, Great Lakes, or within the entire Great Lakes Basin. This spatially structured database could help the development of basin-wide management plans, prioritize locations for funding and specific management actions, track protection and restoration progress, and conduct research for science-based decision making.

  10. BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types

    PubMed Central

    Howe, E.A.; de Souza, A.; Lahr, D.L.; Chatwin, S.; Montgomery, P.; Alexander, B.R.; Nguyen, D.-T.; Cruz, Y.; Stonich, D.A.; Walzer, G.; Rose, J.T.; Picard, S.C.; Liu, Z.; Rose, J.N.; Xiang, X.; Asiedu, J.; Durkin, D.; Levine, J.; Yang, J.J.; Schürer, S.C.; Braisted, J.C.; Southall, N.; Southern, M.R.; Chung, T.D.Y.; Brudz, S.; Tanega, C.; Schreiber, S.L.; Bittker, J.A.; Guha, R.; Clemons, P.A.

    2015-01-01

    BARD, the BioAssay Research Database (https://bard.nih.gov/) is a public database and suite of tools developed to provide access to bioassay data produced by the NIH Molecular Libraries Program (MLP). Data from 631 MLP projects were migrated to a new structured vocabulary designed to capture bioassay data in a formalized manner, with particular emphasis placed on the description of assay protocols. New data can be submitted to BARD with a user-friendly set of tools that assist in the creation of appropriately formatted datasets and assay definitions. Data published through the BARD application program interface (API) can be accessed by researchers using web-based query tools or a desktop client. Third-party developers wishing to create new tools can use the API to produce stand-alone tools or new plug-ins that can be integrated into BARD. The entire BARD suite of tools therefore supports three classes of researcher: those who wish to publish data, those who wish to mine data for testable hypotheses, and those in the developer community who wish to build tools that leverage this carefully curated chemical biology resource. PMID:25477388

  11. BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types.

    PubMed

    Howe, E A; de Souza, A; Lahr, D L; Chatwin, S; Montgomery, P; Alexander, B R; Nguyen, D-T; Cruz, Y; Stonich, D A; Walzer, G; Rose, J T; Picard, S C; Liu, Z; Rose, J N; Xiang, X; Asiedu, J; Durkin, D; Levine, J; Yang, J J; Schürer, S C; Braisted, J C; Southall, N; Southern, M R; Chung, T D Y; Brudz, S; Tanega, C; Schreiber, S L; Bittker, J A; Guha, R; Clemons, P A

    2015-01-01

    BARD, the BioAssay Research Database (https://bard.nih.gov/) is a public database and suite of tools developed to provide access to bioassay data produced by the NIH Molecular Libraries Program (MLP). Data from 631 MLP projects were migrated to a new structured vocabulary designed to capture bioassay data in a formalized manner, with particular emphasis placed on the description of assay protocols. New data can be submitted to BARD with a user-friendly set of tools that assist in the creation of appropriately formatted datasets and assay definitions. Data published through the BARD application program interface (API) can be accessed by researchers using web-based query tools or a desktop client. Third-party developers wishing to create new tools can use the API to produce stand-alone tools or new plug-ins that can be integrated into BARD. The entire BARD suite of tools therefore supports three classes of researcher: those who wish to publish data, those who wish to mine data for testable hypotheses, and those in the developer community who wish to build tools that leverage this carefully curated chemical biology resource. PMID:25477388

  12. Incidence of Guillain-Barré syndrome among patients with Campylobacter infection: a general practice research database study.

    PubMed

    Tam, Clarence C; Rodrigues, Laura C; Petersen, Irene; Islam, Amir; Hayward, Andrew; O'Brien, Sarah J

    2006-07-01

    The association between Campylobacter infection and subsequent Guillain-Barré syndrome (GBS) has been well documented. To date, however, there exists no direct estimate of the incidence of GBS among patients with Campylobacter infection. Using the General Practice Research Database, we estimate the incidence of GBS in a cohort of patients presenting with Campylobacter enteritis to be 1.17/1000 person-years, a rate 77 times greater than that in the general population. The probability that an individual who develops Campylobacter enteritis will also develop GBS during the subsequent 2-month period is <2/10,000. PMID:16741887

  13. Learning, Labour and Union Learning Representatives: Promoting Workplace Learning

    ERIC Educational Resources Information Center

    Ball, Malcolm

    2011-01-01

    The initiative by the Trades Union Congress (TUC) and affiliated trade unions in the UK to appoint trade union learning representatives (ULRs), to promote learning among their members, is a significant development in adult learning. Understandably, the initiative has attracted the attention of academic researchers, but primarily from the…

  14. The Impact of Teacher Unions on Student Learning

    ERIC Educational Resources Information Center

    Fenster, Mark J.

    2009-01-01

    The overall impact of unions and collective bargaining agreements on student achievement has produced a literature with decidedly mixed results. Unions are seen to have both positive and negative influences on a teachers' ability to perform the teaching act. This study researches the impact of unions on state level student achievement, controlling…

  15. Teachers' Perceptions Regarding the Value of a Local Teacher Union

    ERIC Educational Resources Information Center

    Chapman, Sidney L.

    2013-01-01

    Over the past 3 years, teacher union membership has significantly decreased in the state of Georgia. This decrease in union membership is troubling, as previous research has shown that union membership is positively connected to teacher satisfaction and, in turn, to student success. The purpose of this qualitative case study was to determine why…

  16. Immediate Dissemination of Student Discoveries to a Model Organism Database Enhances Classroom-Based Research Experiences

    ERIC Educational Resources Information Center

    Wiley, Emily A.; Stover, Nicholas A.

    2014-01-01

    Use of inquiry-based research modules in the classroom has soared over recent years, largely in response to national calls for teaching that provides experience with scientific processes and methodologies. To increase the visibility of in-class studies among interested researchers and to strengthen their impact on student learning, we have…

  17. Immediate Dissemination of Student Discoveries to a Model Organism Database Enhances Classroom-Based Research Experiences

    ERIC Educational Resources Information Center

    Wiley, Emily A.; Stover, Nicholas A.

    2014-01-01

    Use of inquiry-based research modules in the classroom has soared over recent years, largely in response to national calls for teaching that provides experience with scientific processes and methodologies. To increase the visibility of in-class studies among interested researchers and to strengthen their impact on student learning, we have…

  18. Do Strong Unions Shape District Policies? Collective Bargaining, Teacher Contract Restrictiveness, and the Political Power of Teachers' Unions

    ERIC Educational Resources Information Center

    Strunk, Katharine O.; Grissom, Jason A.

    2010-01-01

    A substantial amount of school district policy is set in the collective bargaining agreements (CBAs) negotiated between teachers' unions and districts. Although previous studies have assumed that CBA provisions bargained by unions are a primary mechanism connecting union strength to outcomes for teachers and students, research has not yet…

  19. Do Strong Unions Shape District Policies? Collective Bargaining, Teacher Contract Restrictiveness, and the Political Power of Teachers' Unions

    ERIC Educational Resources Information Center

    Strunk, Katharine O.; Grissom, Jason A.

    2010-01-01

    A substantial amount of school district policy is set in the collective bargaining agreements (CBAs) negotiated between teachers' unions and districts. Although previous studies have assumed that CBA provisions bargained by unions are a primary mechanism connecting union strength to outcomes for teachers and students, research has not yet…

  20. The influence of family unions and parenthood transitions on self-development.

    PubMed

    Chen, Eva Yi-Ju; Enright, Robert D; Tung, Eli Yi-Liang

    2016-04-01

    The present study discusses the impact of union and parenthood transitions on individuals' self-esteem and sense of mastery development from midadolescence to young adulthood by using multilevel analyses with longitudinal data of 7,339 individuals between ages 15 and 38. The results show that, first, individuals in marital unions show significantly greater rates of growth in self-esteem and sense of mastery, compared with singles. Therefore, entering into marriage provides greater protections to individuals' self-esteem and sense of mastery. Second, the transition to parenthood brings significant decreases in levels and increases in rates of change in self-esteem and sense of mastery among new parents. The degree of the aforementioned changes differs by new parents' gender, union status, and living arrangement with the child at childbirth. Women are influenced more negatively than men. Living with the child at childbirth reduces the degree of decreases in self-esteem and sense of mastery, especially for mothers. In sum, from midadolescence to young adulthood, the development of individuals' self-esteem and sense of mastery is shaped by their union and parenthood transitions. Moreover, the context where these transitions take place, including the type of union and the living arrangement, moderates the degree of the impact. Our findings have important implications for research and practice in promoting the family transition experience. (PsycINFO Database Record PMID:26551657

  1. [Research and development of medical case database: a novel medical case information system integrating with biospecimen management].

    PubMed

    Pan, Shiyang; Mu, Yuan; Wang, Hong; Wang, Tong; Huang, Peijun; Ma, Jianfeng; Jiang, Li; Zhang, Jie; Gu, Bing; Yi, Lujiang

    2010-04-01

    To meet the needs of management of medical case information and biospecimen simultaneously, we developed a novel medical case information system integrating with biospecimen management. The database established by MS SQL Server 2000 covered, basic information, clinical diagnosis, imaging diagnosis, pathological diagnosis and clinical treatment of patient; physicochemical property, inventory management and laboratory analysis of biospecimen; users log and data maintenance. The client application developed by Visual C++ 6.0 was used to implement medical case and biospecimen management, which was based on Client/Server model. This system can perform input, browse, inquest, summary of case and related biospecimen information, and can automatically synthesize case-records based on the database. Management of not only a long-term follow-up on individual, but also of grouped cases organized according to the aim of research can be achieved by the system. This system can improve the efficiency and quality of clinical researches while biospecimens are used coordinately. It realizes synthesized and dynamic management of medical case and biospecimen, which may be considered as a new management platform. PMID:20481307

  2. Automatic detection of lung nodules in computed tomography images: training and validation of algorithms using public research databases

    NASA Astrophysics Data System (ADS)

    Camarlinghi, Niccolò

    2013-09-01

    Lung cancer is one of the main public health issues in developed countries. Lung cancer typically manifests itself as non-calcified pulmonary nodules that can be detected reading lung Computed Tomography (CT) images. To assist radiologists in reading images, researchers started, a decade ago, the development of Computer Aided Detection (CAD) methods capable of detecting lung nodules. In this work, a CAD composed of two CAD subprocedures is presented: , devoted to the identification of parenchymal nodules, and , devoted to the identification of the nodules attached to the pleura surface. Both CADs are an upgrade of two methods previously presented as Voxel Based Neural Approach CAD . The novelty of this paper consists in the massive training using the public research Lung International Database Consortium (LIDC) database and on the implementation of new features for classification with respect to the original VBNA method. Finally, the proposed CAD is blindly validated on the ANODE09 dataset. The result of the validation is a score of 0.393, which corresponds to the average sensitivity of the CAD computed at seven predefined false positive rates: 1/8, 1/4, 1/2, 1, 2, 4, and 8 FP/CT.

  3. Collaborative research between academia and industry using a large clinical trial database: a case study in Alzheimer's disease

    PubMed Central

    2011-01-01

    Background Large clinical trials databases, developed over the course of a comprehensive clinical trial programme, represent an invaluable resource for clinical researchers. Data mining projects sponsored by industry that use these databases, however, are often not viewed favourably in the academic medical community because of concerns that commercial, rather than scientific, goals are the primary purpose of such endeavours. Thus, there are few examples of sustained collaboration between leading academic clinical researchers and industry professionals in a large-scale data mining project. We present here a successful example of this type of collaboration in the field of dementia. Methods The Donepezil Data Repository comprised 18 randomised, controlled trials conducted between 1991 and 2005. The project team at Pfizer determined that the data mining process should be guided by a diverse group of leading Alzheimer's disease clinical researchers called the "Expert Working Group." After development of a list of potential faculty members, invitations were extended and a group of seven members was assembled. The Working Group met regularly with Eisai/Pfizer clinicians and statisticians to discuss the data, identify issues that were currently of interest in the academic and clinical communities that might lend themselves to investigation using these data, and note gaps in understanding or knowledge of Alzheimer's disease that these data could address. Leadership was provided by the Pfizer Clinical Development team leader; Working Group members rotated responsibility for being lead and co-lead for each investigation and resultant publication. Results Six manuscripts, each published in a leading subspecialty journal, resulted from the group's work. Another project resulted in poster presentations at international congresses and two were cancelled due to resource constraints. Conclusions The experience represents a particular approach to optimising the value of data mining of large clinical trial databases for the combined purpose of furthering clinical research and improving patient care. Fruitful collaboration between industry and academia was fostered while the donepezil data repository was used to advance clinical and scientific knowledge. The Expert Working Group approach warrants consideration as a blueprint for conducting similar research ventures in the future. PMID:22029822

  4. NeuPAT: an intranet database supporting translational research in neuroblastic tumors.

    PubMed

    Villamón, Eva; Piqueras, Marta; Meseguer, Javier; Blanquer, Ignacio; Berbegall, Ana P; Tadeo, Irene; Hernández, Vicente; Navarro, Samuel; Noguera, Rosa

    2013-03-01

    Translational research in oncology is directed mainly towards establishing a better risk stratification and searching for appropriate therapeutic targets. This research generates a tremendous amount of complex clinical and biological data needing speedy and effective management. The authors describe the design, implementation and early experiences of a computer-aided system for the integration and management of data for neuroblastoma patients. NeuPAT facilitates clinical and translational research, minimizes the workload in consolidating the information, reduces errors and increases correlation of data through extensive coding. This design can also be applied to other tumor types. PMID:23290604

  5. Propulsion System Airframe Integration Issues and Aerodynamic Database Development for the Hyper-X Flight Research Vehicle

    NASA Technical Reports Server (NTRS)

    Engelund, Walter C.; Holland, Scott D.; Cockrell, Charles E., Jr.; Bittner, Robert D.

    1999-01-01

    NASA's Hyper-X Research Vehicle will provide a unique opportunity to obtain data on an operational airframe integrated scramjet propulsion system at true flight conditions. The airframe integrated nature of the scramjet engine with the Hyper-X vehicle results in a strong coupling effect between the propulsion system operation and the airframe s basic aerodynamic characteristics. Comments on general airframe integrated scramjet propulsion system effects on vehicle aerodynamic performance, stability, and control are provided, followed by examples specific to the Hyper-X research vehicle. An overview is provided of the current activities associated with the development of the Hyper-X aerodynamic database, including wind tunnel test activities and parallel CFD analysis efforts. A brief summary of the Hyper-X aerodynamic characteristics is provided, including the direct and indirect effects of the airframe integrated scramjet propulsion system operation on the basic airframe stability and control characteristics.

  6. U.S. Department of Agriculture Agricultural Research Service Mahantango Creek Watershed, Pennsylvania, United States: long-term stream discharge database

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A long-term streamflow discharge database has been developed by the U.S. Department of Agriculture, Agricultural Research Service, Pasture Systems and Watershed Management Research Unit (PSWMRU) to support intensive hydrologic and water quality research within WE-38, a 7.3 km**2 experimental watersh...

  7. Huntington's Disease and its therapeutic target genes: a global functional profile based on the HD Research Crossroads database

    PubMed Central

    2012-01-01

    Background Huntington’s disease (HD) is a fatal progressive neurodegenerative disorder caused by the expansion of the polyglutamine repeat region in the huntingtin gene. Although the disease is triggered by the mutation of a single gene, intensive research has linked numerous other genes to its pathogenesis. To obtain a systematic overview of these genes, which may serve as therapeutic targets, CHDI Foundation has recently established the HD Research Crossroads database. With currently over 800 cataloged genes, this web-based resource constitutes the most extensive curation of genes relevant to HD. It provides us with an unprecedented opportunity to survey molecular mechanisms involved in HD in a holistic manner. Methods To gain a synoptic view of therapeutic targets for HD, we have carried out a variety of bioinformatical and statistical analyses to scrutinize the functional association of genes curated in the HD Research Crossroads database. In particular, enrichment analyses were performed with respect to Gene Ontology categories, KEGG signaling pathways, and Pfam protein families. For selected processes, we also analyzed differential expression, using published microarray data. Additionally, we generated a candidate set of novel genetic modifiers of HD by combining information from the HD Research Crossroads database with previous genome-wide linkage studies. Results Our analyses led to a comprehensive identification of molecular mechanisms associated with HD. Remarkably, we not only recovered processes and pathways, which have frequently been linked to HD (such as cytotoxicity, apoptosis, and calcium signaling), but also found strong indications for other potentially disease-relevant mechanisms that have been less intensively studied in the context of HD (such as the cell cycle and RNA splicing, as well as Wnt and ErbB signaling). For follow-up studies, we provide a regularly updated compendium of molecular mechanism, that are associated with HD, at http://hdtt.sysbiolab.eu Additionally, we derived a candidate set of 24 novel genetic modifiers, including histone deacetylase 3 (HDAC3), metabotropic glutamate receptor 1 (GRM1), CDK5 regulatory subunit 2 (CDK5R2), and coactivator 1ß of the peroxisome proliferator-activated receptor gamma (PPARGC1B). Conclusions The results of our study give us an intriguing picture of the molecular complexity of HD. Our analyses can be seen as a first step towards a comprehensive list of biological processes, molecular functions, and pathways involved in HD, and may provide a basis for the development of more holistic disease models and new therapeutics. PMID:22741533

  8. The institute for genomic research Osa1 rice genome annotation database.

    PubMed

    Yuan, Qiaoping; Ouyang, Shu; Wang, Aihui; Zhu, Wei; Maiti, Rama; Lin, Haining; Hamilton, John; Haas, Brian; Sultana, Razvan; Cheung, Foo; Wortman, Jennifer; Buell, C Robin

    2005-05-01

    We have developed a rice (Oryza sativa) genome annotation database (Osa1) that provides structural and functional annotation for this emerging model species. Using the sequence of O. sativa subsp. japonica cv Nipponbare from the International Rice Genome Sequencing Project, pseudomolecules, or virtual contigs, of the 12 rice chromosomes were constructed. Our most recent release, version 3, represents our third build of the pseudomolecules and is composed of 98% finished sequence. Genes were identified using a series of computational methods developed for Arabidopsis (Arabidopsis thaliana) that were modified for use with the rice genome. In release 3 of our annotation, we identified 57,915 genes, of which 14,196 are related to transposable elements. Of these 43,719 non-transposable element-related genes, 18,545 (42.4%) were annotated with a putative function, 5,777 (13.2%) were annotated as encoding an expressed protein with no known function, and the remaining 19,397 (44.4%) were annotated as encoding a hypothetical protein. Multiple splice forms (5,873) were detected for 2,538 genes, resulting in a total of 61,250 gene models in the rice genome. We incorporated experimental evidence into 18,252 gene models to improve the quality of the structural annotation. A series of functional data types has been annotated for the rice genome that includes alignment with genetic markers, assignment of gene ontologies, identification of flanking sequence tags, alignment with homologs from related species, and syntenic mapping with other cereal species. All structural and functional annotation data are available through interactive search and display windows as well as through download of flat files. To integrate the data with other genome projects, the annotation data are available through a Distributed Annotation System and a Genome Browser. All data can be obtained through the project Web pages at http://rice.tigr.org. PMID:15888674

  9. Confronting Ambiguity, Anarchy, and Crisis in Institutional Research: Using Student Unit Record Databases in Extra-Institutional Research

    ERIC Educational Resources Information Center

    Musoba, Glenda D.; Gross, Jacob P. K.; Hossler, Don

    2008-01-01

    The world of policymaking on the campuses of colleges and universities is messy, ambiguous, and contested. In this complex environment, which Kingdon (2003) has aptly called a "policy soup," the role of institutional research is often not only to provide answers to existing policy questions but to produce information to help transform ambiguity…

  10. Gypsy moths: Pest control research. (Latest citations from the Life Sciences Collection database). Published Search

    SciTech Connect

    Not Available

    1993-06-01

    The bibliography contains citations concerning control and research regarding gypsy moths or lymantria dispar. Both natural and synthetic controls are discussed, including parasites, viral diseases, fungal diseases, bird predation, bacterial diseases, pheromone trapping, insecticides, and physical and chemical localized protection. Laboratory and field studies on sex pheromones, environmental effects on life cycles, effects of feeding behavior, plant-insect interactions, and other research relating to the control of this forest pest are considered. (Contains 250 citations and includes a subject term index and title list.)

  11. Recycling rubber wastes. (Latest citations from the Rubber and Plastics Research Association database). Published Search

    SciTech Connect

    1995-02-01

    The bibliography contains citations concerning research and innovations in the recycling of rubber wastes. Recycling methods and equipment, applications of recycled rubber, and energy recovery systems and performance are among the topics discussed. Recycling methods compared and contrasted with various rubber waste disposal techniques are also included. (Contains a minimum of 96 citations and includes a subject term index and title list.)

  12. Recycling rubber wastes. (Latest citations from the rubber and plastics research association database). Published Search

    SciTech Connect

    Not Available

    1994-05-01

    The bibliography contains citations concerning research and innovations in the recycling of rubber wastes. Recycling methods and equipment, applications of recycled rubber, and energy recovery systems and performance are among the topics discussed. Recycling methods compared and contrasted with various rubber waste disposal techniques are also included. (Contains a minimum of 89 citations and includes a subject term index and title list.)

  13. Sustainability in the Union

    ERIC Educational Resources Information Center

    Brown, Patrick; Taylor, John

    2012-01-01

    Operating as the center of student life, college unions have a central role to teach citizenship, social responsibility, and leadership. Unions can serve as locations for education and conversations about sustainability, as well as for organizations operationally and programmatically engaged in sustainable practices. In this chapter, the authors…

  14. Power in a Union

    ERIC Educational Resources Information Center

    Johnson, Pam

    2009-01-01

    The work unions do in providing and supporting learning for their members rarely makes the news headlines, but it will be essential if people are to engage those workers who most need to acquire new and better skills to cope in the economic downturn. In this article, the author talks about the power in a union and describes UNISON, a comparatively…

  15. Teacher Unions 101

    ERIC Educational Resources Information Center

    Koppich, Julia E.

    2012-01-01

    Teacher unions are hard to miss in the news lately. Newspapers, blogs, social media posts, magazine articles, and political speeches abound with talk of them. Teacher unions are a hot topic and one that probably was not covered in college classes. The noisy back-and-forth among partisans can be both mind-numbing and confusing, often creating a…

  16. Governance: Senates and Unions.

    ERIC Educational Resources Information Center

    Polishook, Irwin H.; Naples, Caesar J.

    1989-01-01

    Edited versions of two conference papers are presented. The first paper, "The Debate Over Academic Unions and Faculty Governance," by Irwin H. Polishook, discusses why the concept of collective bargaining continues to be a significant issue in academe and is considered to be incompatible with faculty governance. It examines the union experiences…

  17. [Unionization on Campus].

    ERIC Educational Resources Information Center

    Douglas, Joel M., Ed.

    1982-01-01

    This newsletter issue considers in separate articles: (1) unionization in 1981 among college faculty in the United States; (2) unionization at the California State University and College System (CSU) (by Lisa Flanzraich); (3) multi-year agreements; (4) contract size; (5) and, in "Yeshivawatch," developments pertaining to the National Labor…

  18. Teacher Unions 101

    ERIC Educational Resources Information Center

    Koppich, Julia E.

    2012-01-01

    Teacher unions are hard to miss in the news lately. Newspapers, blogs, social media posts, magazine articles, and political speeches abound with talk of them. Teacher unions are a hot topic and one that probably was not covered in college classes. The noisy back-and-forth among partisans can be both mind-numbing and confusing, often creating a…

  19. Sustainability in the Union

    ERIC Educational Resources Information Center

    Brown, Patrick; Taylor, John

    2012-01-01

    Operating as the center of student life, college unions have a central role to teach citizenship, social responsibility, and leadership. Unions can serve as locations for education and conversations about sustainability, as well as for organizations operationally and programmatically engaged in sustainable practices. In this chapter, the authors…

  20. Update on the profile of the EUSTAR cohort: an analysis of the EULAR Scleroderma Trials and Research group database.

    TOXLINE Toxicology Bibliographic Information

    Meier FM; Frommer KW; Dinser R; Walker UA; Czirjak L; Denton CP; Allanore Y; Distler O; Riemekasten G; Valentini G; Müller-Ladner U; EUSTAR Co-authors

    2012-08-01

    OBJECTIVES: Systemic sclerosis (SSc) is a rare disease requiring multicentre collaboration to reveal comprehensive details of disease-related causes for morbidity and mortality.METHODS: The European League Against Rheumatism (EULAR) Scleroderma Trials and Research (EUSTAR) group initiated a database to prospectively gather key data of patients with SSc using a minimal essential dataset that was reorganised in 2008 introducing new items. Baseline visit data of patients who were registered between 2004 and 2011 were analysed using descriptive statistics.RESULTS: In June 2011, 7655 patients (2838 with diffuse cutaneous (dc) and 4481 with limited cutaneous (lc) SSc who fulfilled the American College of Rheumatology diagnostic criteria had been registered in 174 centres, mainly European. The most prominent hallmarks of disease were Raynaud's phenomenon (96.3%), antinuclear antibodies (93.4%) and a typical capillaroscopic pattern (90.9%). Scleroderma was more common on fingers and hands than on any other part of the skin. Proton pump inhibitors (65.2%), calcium channel blockers (52.7%), and corticosteroids (45.3%) were most often prescribed. Among the immunosuppressant agents, cyclophosphamide was used more often in dcSSc than in lcSSc.CONCLUSIONS: The EUSTAR database provides an abundance of information on the true clinical face of SSc that will be helpful in improving the classification of SSc and its subsets and for developing more specific therapeutic recommendations.

  1. The Process of Installing REDCap, a Web Based Database Supporting Biomedical Research

    PubMed Central

    Mare, I.; Hazelhurst, S.; Kramer, B.

    2014-01-01

    Summary Background Clinical and research data are essential for patient care, research and healthcare system planning. REDCapTM is a web-based tool for research data curatorship developed at Vanderbilt University in Nashville, USA. The Faculty of Health Sciences at the University of the Witwatersrand, Johannesburg South Africa identified the need for a cost effective data management instrument. REDCap was installed as per the user agreement with Vanderbilt University in August 2012. Objectives In order to assist other institutions that may lack the in-house Information Technology capacity, this paper describes the installation and support of REDCap and incorporates an analysis of user uptake over the first year of use. Methods We reviewed the staffing requirements, costs of installation, process of installation and necessary infrastructure and end-user requests following the introduction of REDCap at Wits. The University Legal Office and Human Research Ethics Committee were consulted regarding the REDCap end-user agreement. Bi-monthly user meetings resulted in a training workshop in August 2013. We compared our REDCap software user numbers and records before and after the first training workshop. Results Human resources were recruited from existing staff. Installation costs were limited to servers and security certificates. The total costs to provide a functional REDCap platform was less than $9000. Eighty-one (81) users were registered in the first year. After the first training workshop the user numbers increased by 59 in one month and the total number of active users to 140 by the end of August 2013. Custom software applications for REDCap were created by collaboration between clinicians and software developers. Conclusion REDCap was installed and maintained at limited cost. A small number of people with defined skills can support multiple REDCap users in two to four hours a week. End user training increased in the number of users, number of projects created and the number of projects moved to production. PMID:25589907

  2. Recycling rubber wastes. (Latest citations from the Rubber and Plastics Research Association database). Published Search

    SciTech Connect

    1996-04-01

    The bibliography contains citations concerning research and innovations in the recycling of rubber wastes. Recycling methods and equipment, applications of recycled rubber, and energy recovery systems and performance are among the topics discussed. Recycling methods compared and contrasted with various rubber waste disposal techniques are also included. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  3. Phoenix Union High School District #210 Adult Academy Evaluation Report, 1980-81. Research Services Report No. 33:08:80/81:010.

    ERIC Educational Resources Information Center

    Norris, Carol A.; Wheeler, Linda

    The Adult Reading Academy, a federally-funded service of the Phoenix Union High School District, serves native- and foreign-born adult students who are deficient in the basic skills of reading, writing, arithmetic, and oral communication. In 1980/81, the program served 476 students at 17 sites. Approximately 24 percent of the clients served were…

  4. The Cerebral Blood Flow Biomedical Informatics Research Network (CBFBIRN) database and analysis pipeline for arterial spin labeling MRI data

    PubMed Central

    Shin, David D.; Ozyurt, I. Burak; Liu, Thomas T.

    2013-01-01

    Arterial spin labeling (ASL) is a magnetic resonance imaging technique that provides a non-invasive and quantitative measure of cerebral blood flow (CBF). After more than a decade of active research, ASL is now emerging as a robust and reliable CBF measurement technique with increased availability and ease of use. There is a growing number of research and clinical sites using ASL for neuroscience research and clinical care. In this paper, we present an online CBF Database and Analysis Pipeline, collectively called the Cerebral Blood Flow Biomedical Informatics Research Network (CBFBIRN) that allows researchers to upload and share ASL and clinical data. In addition to serving the role as a central data repository, the CBFBIRN provides a streamlined data processing infrastructure for CBF quantification and group analysis, which has the potential to accelerate the discovery of new scientific and clinical knowledge. All capabilities and features built into the CBFBIRN are accessed online using a web browser through a secure login. In this work, we begin with a general description of the CBFBIRN system data model and its architecture, then devote the remainder of the paper to the CBFBIRN capabilities. The latter part of our work is divided into two processing modules: (1) Data Upload and CBF Quantification Module; (2) Group Analysis Module that supports three types of analysis commonly used in neuroscience research. To date, the CBFBIRN hosts CBF maps and associated clinical data from more than 1,300 individual subjects. The data have been contributed by more than 20 different research studies, investigating the effect of various conditions on CBF including Alzheimer’s, schizophrenia, bipolar disorder, depression, traumatic brain injury, HIV, caffeine usage, and methamphetamine abuse. Several example results, generated by the CBFBIRN processing modules, are presented. We conclude with the lessons learned during implementation and deployment of the CBFBIRN and our experience in promoting data sharing. PMID:24151465

  5. Research on an expert system for database operation of simulation-emulation math models. Volume 1, Phase 1: Results

    NASA Technical Reports Server (NTRS)

    Kawamura, K.; Beale, G. O.; Schaffer, J. D.; Hsieh, B. J.; Padalkar, S.; Rodriguez-Moscoso, J. J.

    1985-01-01

    The results of the first phase of Research on an Expert System for Database Operation of Simulation/Emulation Math Models, is described. Techniques from artificial intelligence (AI) were to bear on task domains of interest to NASA Marshall Space Flight Center. One such domain is simulation of spacecraft attitude control systems. Two related software systems were developed to and delivered to NASA. One was a generic simulation model for spacecraft attitude control, written in FORTRAN. The second was an expert system which understands the usage of a class of spacecraft attitude control simulation software and can assist the user in running the software. This NASA Expert Simulation System (NESS), written in LISP, contains general knowledge about digital simulation, specific knowledge about the simulation software, and self knowledge.

  6. Heart research advances using database search engines, Human Protein Atlas and the Sydney Heart Bank.

    PubMed

    Li, Amy; Estigoy, Colleen; Raftery, Mark; Cameron, Darryl; Odeberg, Jacob; Pontén, Fredrik; Lal, Sean; Dos Remedios, Cristobal G

    2013-10-01

    This Methodological Review is intended as a guide for research students who may have just discovered a human "novel" cardiac protein, but it may also help hard-pressed reviewers of journal submissions on a "novel" protein reported in an animal model of human heart failure. Whether you are an expert or not, you may know little or nothing about this particular protein of interest. In this review we provide a strategic guide on how to proceed. We ask: How do you discover what has been published (even in an abstract or research report) about this protein? Everyone knows how to undertake literature searches using PubMed and Medline but these are usually encyclopaedic, often producing long lists of papers, most of which are either irrelevant or only vaguely relevant to your query. Relatively few will be aware of more advanced search engines such as Google Scholar and even fewer will know about Quertle. Next, we provide a strategy for discovering if your "novel" protein is expressed in the normal, healthy human heart, and if it is, we show you how to investigate its subcellular location. This can usually be achieved by visiting the website "Human Protein Atlas" without doing a single experiment. Finally, we provide a pathway to discovering if your protein of interest changes its expression level with heart failure/disease or with ageing. PMID:23856366

  7. How to Campaign and Win When the Union Is Against You.

    ERIC Educational Resources Information Center

    Oden, Don

    1982-01-01

    Board members running for reelection against teacher union opposition should differentiate classroom teachers from the union, promote their board experience, research the issues, prepare early for the campaign, analyze the reasons for union opposition, anticipate psychological warfare, mount a positive defense, admit mistakes, and turn union…

  8. An integrated, ontology-driven approach to constructing observational databases for research.

    PubMed

    Hsu, William; Gonzalez, Nestor R; Chien, Aichi; Pablo Villablanca, J; Pajukanta, Päivi; Viñuela, Fernando; Bui, Alex A T

    2015-06-01

    The electronic health record (EHR) contains a diverse set of clinical observations that are captured as part of routine care, but the incomplete, inconsistent, and sometimes incorrect nature of clinical data poses significant impediments for its secondary use in retrospective studies or comparative effectiveness research. In this work, we describe an ontology-driven approach for extracting and analyzing data from the patient record in a longitudinal and continuous manner. We demonstrate how the ontology helps enforce consistent data representation, integrates phenotypes generated through analyses of available clinical data sources, and facilitates subsequent studies to identify clinical predictors for an outcome of interest. Development and evaluation of our approach are described in the context of studying factors that influence intracranial aneurysm (ICA) growth and rupture. We report our experiences in capturing information on 78 individuals with a total of 120 aneurysms. Two example applications related to assessing the relationship between aneurysm size, growth, gene expression modules, and rupture are described. Our work highlights the challenges with respect to data quality, workflow, and analysis of data and its implications toward a learning health system paradigm. PMID:25817919

  9. Plant and Crop Databases

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Databases have become an integral part of all aspects of biological research, including basic and applied plant biology. The importance of databases continues to increase as the volume of data from direct and indirect genomics approaches expands. What is not always obvious to users of databases is t...

  10. Holocene = Anthropocene? The HYDE database for integrated global change research over the past 12,000 years

    NASA Astrophysics Data System (ADS)

    Klein Goldewijk, K.

    2008-12-01

    More and more studies of global (climate) change are focusing on the past. Hundreds and thousands of years of land use, driven by population growth have left their trace/mark on the Earth's surface. We are only at the beginning to understand the complex relationship of human induced disturbances of the global environment, and the consequences for future climate. It is therefore essential that we get a clear picture/understanding of past relationships between population growth, land use and climate. In order to facilitate climate modelers to examine these relationships, the HYDE database has been updated and extended. The update of HYDE described here (Klein Goldewijk et al. 2006; Klein Goldewijk et al. 2007) includes several improvements compared to its predecessor: (i) the HYDE 2 version used a Boolean approach with a 30 minute degree resolution, while HYDE 3 uses fractional land use on a 5 minute resolution; (ii) more and better sub-national (population) data (Klein Goldewijk, 2005) to improve the historical (urban and rural) population maps as a basis for allocation of land cover; (iii) implementation of different allocation algorithms with time-dependent weighting maps for cropland and grassland; (iv) the period covered has now been extended from the emergence of agriculture (10,000 B.C) to present time (2,000 A.D.), with different time intervals. Examples of (future) use of the database is to help test the 'Ruddiman hypothesis', who proposed a theory that mankind already altered the global atmosphere much earlier than the start of the Industrial Revolution in the early 18th century (Ruddiman, 2003), which put forward the research question whether we detect a pre- Industrial Revolution anthropogenic signal, and how strong is that signal? References Klein Goldewijk, K. A.F. Bouwman and G. van Drecht, 2007. Mapping current global cropland and grassland distributions on a 5 by 5 minute resolution, Journal of Land Use Science, Vol 2(3): 167-190. Klein Goldewijk, K. and G. van Drecht, 2006. HYDE 3: Current and historical population and land cover. MNP (2006) (Edited by A.F. Bouwman, T. Kram and K. Klein Goldewijk), Integrated modelling of global environmental change. An overview of IMAGE 2.4. Netherlands Environmental Assessment Agency (MNP), Bilthoven, The Netherlands Klein Goldewijk, K. 2005. Three centuries of global population growth: A spatial referenced population density database for 1700 - 2000, Population and Environment, 26 (5): 343-367. Ruddiman, WF, 2003. The anthropogenic greenhouse era bagan thousands of years ago, Climatic Change, 61(3), 261-293.

  11. An open-database of Grape Harvest dates for climate research: data description and quality assessment

    NASA Astrophysics Data System (ADS)

    Daux, V.; Garcia de Cortazar-Atauri, I.; Yiou, P.; Chuine, I.; Garnier, E.; Ladurie, E. Le Roy; Mestre, O.; Tardaguila, J.

    2011-11-01

    We present a dataset of grape harvest dates (GHD) series that has been compiled from international and non-translated French and Spanish literature and from unpublished documentary sources from public organizations and from wine-growers. As of June 2011, this GHD dataset comprises 378 series mainly from France (93% of the data) as well as series from Switzerland, Italy, Spain and Luxembourg. The series have variable length and contain gaps of variable sizes. The longest and most complete ones are from Burgundy, Switzerland, Southern Rhône valley, Jura and Ile-de-France. The GHD series were grouped into 27 regions according to their location, to geomorphological and geological criteria, and to past and present grape varieties. The GHD regional composite series (GHD-RCS) were calculated and compared pairwise to assess the quality of the series. Significant (p-value < 0.001) and strong correlations exist between most of them. As expected, the correlations tended to be higher when the vineyards are closer, the highest correlation (R = 0.91) being obtained between the High Loire Valley and the Ile-de-France GHD-RCS. The strong dependence of vine cycle on temperature and, therefore, the strong link between GHD and the temperature of the growing season was also used to test the quality of the GHD series. The strongest correlations are obtained between the GHD-RCS and the temperature series of the nearest weather stations. Moreover, the GHD-RCS/temperature correlation maps show spatial patterns similar to temperature correlation maps. The stability of the correlations over time is explored. The most striking feature is their generalized deterioration at the late 19th-early 20th turning point. The possible effects on the GHD of the phylloxera crisis, which took place at this time, are discussed. The median of the standardized GHD-RCS was calculated. The distribution of the extreme years of this general synthetic series is not homogenous. Extremely late years all occur during a two-century long time-window from the early 17th to the early 19th century, while extremely early years are frequent during the 16th and since the mid-19th century. The dataset is made accessible for climate research through the Internet. It should allow a variety of climate studies, including reconstructions of atmospheric circulation over Western Europe.

  12. Veterans Administration Databases

    Cancer.gov

    The Veterans Administration Information Resource Center provides database and informatics experts, customer service, expert advice, information products, and web technology to VA researchers and others.

  13. Labor unions: a public health institution.

    PubMed

    Malinowski, Beth; Minkler, Meredith; Stock, Laura

    2015-02-01

    Using a social-ecological framework, we drew on a targeted literature review and historical and contemporary cases from the US labor movement to illustrate how unions address physical and psychosocial conditions of work and the underlying inequalities and social determinants of health. We reviewed labor involvement in tobacco cessation, hypertension control, and asthma, limiting articles to those in English published in peer-reviewed public health or medical journals from 1970 to 2013. More rigorous research is needed on potential pathways from union membership to health outcomes and the facilitators of and barriers to union-public health collaboration. Despite occasional challenges, public health professionals should increase their efforts to engage with unions as critical partners. PMID:25521905

  14. Native Health Research Database

    MedlinePLUS

    ... Center MSC09 5100 1 University of New Mexico Albuquerque, NM 87131-0001 Native Services Librarian Phone: (505) ... salud.unm.edu © The University of New Mexico, Albuquerque, NM 87131, (505) 277-0111 Disclaimer Privacy Statement ...

  15. Design and development of portal for biological database in agriculture

    PubMed Central

    Lal, Shashi Bhushan; Pandey, Pankaj Kumar; Rai, Punit K; Rai, Anil; Sharma, Anu; Chaturvedi, Krishna Kumar

    2013-01-01

    The application of novel and modern techniques in genetic engineering and genomics has resulted in information explosion in genomics. Three major genome databases under International Nucleotide Sequence Database collaboration NCBI, DDBJ and EMBL have been providing a convenient platform for submission of sequences which they share among themselves. Many institutes in India under Indian Council of Agricultural Research have scientists working on biotechnology and bioinformatics research. The various studies conducted by them, generate massive data related to biological information of plants, animals, insects, microbes and fisheries. These scientists are dependent on NCBI, EMBL, DDBJ and other portals for their sequence submissions, analysis and other data mining tasks. Due to various limitations imposed on these sites and the poor connectivity problem prevents them to conduct their studies on these open domain databases. The valued information generated by them needs to be shared by the scientific communities to eliminate the duplication of efforts and expedite their knowledge extended towards new findings. A secured common submission portal system with user-friendly interfaces, integrated help and error checking facilities has been developed in such a way that the database at the backend consists of a union of the items available on the above mentioned databases. Standard database management concepts have been employed for their systematic storage management. Extensive hardware resources in the form of high performance computing facility are being installed for deployment of this portal. Availability http://cabindb.iasri.res.in:8080/sequence_portal/ PMID:23888101

  16. Data Conversion and Indexing: How To Get the Most out of Your Machine-Readable Database. DataResearch Automation Guide Series, Number Two.

    ERIC Educational Resources Information Center

    Data Research Associates, Inc., St. Louis, MO.

    In today's library environment, the library's most important asset is its machine-readable database. In order to maintain this investment, Data Research Associates provides several comprehensive data conversion services, including retrospective conversion and authority control. For bibliographic records not yet in MARC (machine readable…

  17. Providing Database Services in a Nationwide Research Organisation--Coexistence of Traditional Information Services and a Modern CD-ROM/Online Hybrid Solution.

    ERIC Educational Resources Information Center

    Bowman, Benjamin F.

    For the past two decades the central Information Retrieval Services of the Max Planck Society has been providing database searches for scientists in Max Planck Institutes and Research Groups throughout Germany. As a supplement to traditional search services offered by professional intermediaries, they have recently fostered the introduction of a…

  18. Alaska Geothermal Sites Map and Database: Bringing together legacy and new geothermal data for research, exploration and development

    NASA Astrophysics Data System (ADS)

    Clough, J. G.; Harun, N. T.; Hughes, C. A.; Weakland, J. R.; Cameron, C. E.

    2013-12-01

    Geothermal exploration activities in Alaska from the late 1970s into the 1980s generated vast quantities of scientific data that currently is in unpublished, forgotten and obscure, as well as published formats. Alaska has 61 hot springs (hotter than 50°C) and 34 'warm to cool springs' (cooler than 50°C). Thirty-seven thermal springs are located within the Aleutian and Alaska Peninsula volcanic arc into and are related to elevated heat flows in areas of arc volcanism as well as crustal scale faults associated with accretionary tectonism. The central interior belt that extends from the Seward Peninsula to Circle Hot Springs contains 37 thermal springs that formed due to mostly extensional tectonic forces. An additional 17 thermal springs are in southeast Alaska and 4 are in the Wrangell Mountains. A new cycle of geothermal exploration is underway in Alaska and is producing a wealth of new geothermal data. The Alaska Division of Geological and Geophysical Surveys (ADGGS), funded by the National Geothermal Data System, is compiling both new and legacy geothermal data into a comprehensive database accessible on the ADGGS website. ADGGS has created a new ';Geothermal Sites of Alaska Map' and associated database that includes data on geothermal hot springs, direct use of geothermal resources, volcanic vents, aqueous geochemistry, borehole temperatures, core descriptions, rock chemistry, earthquakes in proximity to hot springs, and active faults. Geothermal hot springs includes locality, temperature, flow rate, sources and related resources. Direct use of geothermal resources contains facilities, capacity, energy use, temperature, flow rate and contact information from geothermal hot springs that are or have recently been used for recreational use, space heating, agricultural or energy use. Volcanic vents records 395 volcanic vents and fumaroles throughout the state that are Holocene or younger. It includes their age, location, elevation, geologic history, composition, and information source. Aqueous geochemistry, a compilation of aqueous chemistry, free gas and isotopes analyses. Aqueous geochemical analyses consist of 407 aqueous geochemical analyses from 85 geothermal sites throughout Alaska. This template also includes 106 free gas analyses from 31 geothermal sites. Isotopic analyses (285) of waters from 42 geothermal sites are also contained in this geochemical data. Borehole temperature data from geothermal, and oil and gas wells are presented along with thermal depth profiles where available. Earthquakes in proximity to hot springs consists of 1,975 earthquakes that are within 5 km of thermal hot springs and may be used to detect underground movement of thermal waters. Active faults comprises active faults across Alaska (1,527) including fault type, location, orientation and slip rate. Additionally, a new comprehensive and searchable Alaska geothermal bibliography, with links to downloadable reference sources was created during this study. The completed Alaska geothermal sites map and database will be accessible to the public and industry and will enable research and development of geothermal sites in Alaska.

  19. Prototype of an Integrated Hurricane Information System for Research: Design and Implementation of the Database and Web Portal

    NASA Astrophysics Data System (ADS)

    Li, P. P.; Knosp, B.; Vu, Q. A.; Hristova-Veleva, S.; Chao, Y.; Vane, D.; Lambrigtsen, B.; Su, H.; Dang, V.; Fovell, R.; Willis, J.; Tanelli, S.; Fishbein, E.; Ao, C. O.; Poulsen, W. L.; Park, K. J.; Fetzer, E.; Vazquez, J.; Callahan, P. S.; Marcus, S.; Garay, M.; Kahn, R.; Haddad, Z.

    2007-12-01

    Many hurricane websites provide historical hurricane information and real-time storm tracking. These sites often include images from various remote-sensing satellite sensors with such atmospheric and oceanic quantities as wind, temperature, rain, and water vapor. However, it has been determined that the hurricane analysis community is lacking a web portal that provides researchers a comprehensive set of observed hurricane parameters (both graphics and data) together with large-scale and convection-resolving model output. We have developed a prototype of an integrated hurricane information system of high-resolution satellite and in- situ observations along with model outputs pertaining to: i) the thermodynamic and microphysical structure of storms; ii) the air-sea interaction processes; iii) the larger-scale environment as depicted by quantities such as SST, ocean heat content and the aerosol loading of the environment. Our goal is to provide a one-stop place to access all the available information of a specific hurricane for researchers to advance the understanding, modeling and predication of hurricane genesis and intensity changes. Our hurricane information system prototype consists of high-resolution satellite data measuring three- dimensional atmospheric and oceanic parameters that includes observations from AIRS, MISR, MODIS, CloudSAT, AMSR-E, TRMM, GOES, MLS, QuikSCAT, SeaWiFS, and COSMIC GPS, in-situ observations such as ARGO floats, large scale data assimilation products from NCEP, and high resolution hurricane model output from WRF. High-resolution satellite data are sub-setted within 2000-kilometer-square area centered at the closest storm location and large-scale environmental datasets are divided into 6 predefined geographical regions. When accessing this hurricane portal, users may browse through data by year, region, category, and hurricane. At the front page, we show the hurricane track using Google Map. Users may pan and zoom, or click on the track location placemark to see the time, location, and the intensity of the hurricane. Large scale datasets, such as SST or aerosol optical depth can be overlaid on top of the hurricane track in Google Map. In addition, available satellite and in-situ data during the hurricane period are displayed as little bars in a time line organized by datasets. When clicking a little bar, pre-generated plots for the selected dataset will be displayed in a separate window together with all other datasets co-located around the same time. The raw data in user-specified format can be downloaded for further analysis or model integration. As for the 3D model data, Live Access Server (LAS) is used to provide custom subsets and on-the-fly visualization. The site is dynamically configured using a backend relational database that is designed to let users easily browse through the website to find data and plots that are pertinent to their research. In this presentation, we will describe the current status of the integrated hurricane information system prototype, the design and the implementation of the hurricane database and portal, and future enhancements.

  20. Soviet Union's Energy Situation

    SciTech Connect

    Not Available

    1991-05-01

    The Soviet Union is a country of vast sources of energy supply including oil, natural gas, coal, uranium, and hydropower, all of which are used in varying degrees to supply its energy needs. In spite of this wealth of resources, the Soviet Union has difficulty meeting its demand for energy. Opinions on the situation vary, from those who claim the country is in the midst of an energy crisis to those who argue that distribution is the only difficulty. But in any event, the unfortunate fact is that in some areas of the country, energy needs exceed its availability. Until recently, soviet energy policy concentrated on supply. With the release of its 1983 Energy Program however, the Soviet Union acknowledged the necessity of a fundamental shift in energy policy from the supply side to the demand side in order to curb energy consumption.

  1. Constructing a Geology Ontology Using a Relational Database

    NASA Astrophysics Data System (ADS)

    Hou, W.; Yang, L.; Yin, S.; Ye, J.; Clarke, K.

    2013-12-01

    In geology community, the creation of a common geology ontology has become a useful means to solve problems of data integration, knowledge transformation and the interoperation of multi-source, heterogeneous and multiple scale geological data. Currently, human-computer interaction methods and relational database-based methods are the primary ontology construction methods. Some human-computer interaction methods such as the Geo-rule based method, the ontology life cycle method and the module design method have been proposed for applied geological ontologies. Essentially, the relational database-based method is a reverse engineering of abstracted semantic information from an existing database. The key is to construct rules for the transformation of database entities into the ontology. Relative to the human-computer interaction method, relational database-based methods can use existing resources and the stated semantic relationships among geological entities. However, two problems challenge the development and application. One is the transformation of multiple inheritances and nested relationships and their representation in an ontology. The other is that most of these methods do not measure the semantic retention of the transformation process. In this study, we focused on constructing a rule set to convert the semantics in a geological database into a geological ontology. According to the relational schema of a geological database, a conversion approach is presented to convert a geological spatial database to an OWL-based geological ontology, which is based on identifying semantics such as entities, relationships, inheritance relationships, nested relationships and cluster relationships. The semantic integrity of the transformation was verified using an inverse mapping process. In a geological ontology, an inheritance and union operations between superclass and subclass were used to present the nested relationship in a geochronology and the multiple inheritances relationship. Based on a Quaternary database of downtown of Foshan city, Guangdong Province, in Southern China, a geological ontology was constructed using the proposed method. To measure the maintenance of semantics in the conversation process and the results, an inverse mapping from the ontology to a relational database was tested based on a proposed conversation rule. The comparison of schema and entities and the reduction of tables between the inverse database and the original database illustrated that the proposed method retains the semantic information well during the conversation process. An application for abstracting sandstone information showed that semantic relationships among concepts in the geological database were successfully reorganized in the constructed ontology. Key words: geological ontology; geological spatial database; multiple inheritance; OWL Acknowledgement: This research is jointly funded by the Specialized Research Fund for the Doctoral Program of Higher Education of China (RFDP) (20100171120001), NSFC (41102207) and the Fundamental Research Funds for the Central Universities (12lgpy19).

  2. Southern African Treatment Resistance Network (SATuRN) RegaDB HIV drug resistance and clinical management database: supporting patient management, surveillance and research in southern Africa.

    PubMed

    Manasa, Justen; Lessells, Richard; Rossouw, Theresa; Naidu, Kevindra; Van Vuuren, Cloete; Goedhals, Dominique; van Zyl, Gert; Bester, Armand; Skingsley, Andrew; Stott, Katharine; Danaviah, Siva; Chetty, Terusha; Singh, Lavanya; Moodley, Pravi; Iwuji, Collins; McGrath, Nuala; Seebregts, Christopher J; de Oliveira, Tulio

    2014-01-01

    Substantial amounts of data have been generated from patient management and academic exercises designed to better understand the human immunodeficiency virus (HIV) epidemic and design interventions to control it. A number of specialized databases have been designed to manage huge data sets from HIV cohort, vaccine, host genomic and drug resistance studies. Besides databases from cohort studies, most of the online databases contain limited curated data and are thus sequence repositories. HIV drug resistance has been shown to have a great potential to derail the progress made thus far through antiretroviral therapy. Thus, a lot of resources have been invested in generating drug resistance data for patient management and surveillance purposes. Unfortunately, most of the data currently available relate to subtype B even though >60% of the epidemic is caused by HIV-1 subtype C. A consortium of clinicians, scientists, public health experts and policy markers working in southern Africa came together and formed a network, the Southern African Treatment and Resistance Network (SATuRN), with the aim of increasing curated HIV-1 subtype C and tuberculosis drug resistance data. This article describes the HIV-1 data curation process using the SATuRN Rega database. The data curation is a manual and time-consuming process done by clinical, laboratory and data curation specialists. Access to the highly curated data sets is through applications that are reviewed by the SATuRN executive committee. Examples of research outputs from the analysis of the curated data include trends in the level of transmitted drug resistance in South Africa, analysis of the levels of acquired resistance among patients failing therapy and factors associated with the absence of genotypic evidence of drug resistance among patients failing therapy. All these studies have been important for informing first- and second-line therapy. This database is a free password-protected open source database available on www.bioafrica.net. Database URL: http://www.bioafrica.net/regadb/ PMID:24504151

  3. Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials And Research group database

    PubMed Central

    Walker, U A; Tyndall, A; Czirják, L; Denton, C; Farge?Bancel, D; Kowal?Bielecka, O; Müller?Ladner, U; Bocelli?Tyndall, C; Matucci?Cerinic, M

    2007-01-01

    Background Systemic sclerosis (SSc) is a multisystem autoimmune disease, which is classified into a diffuse cutaneous (dcSSc) and a limited cutaneous (lcSSc) subset according to the skin involvement. In order to better understand the vascular, immunological and fibrotic processes of SSc and to guide its treatment, the EULAR Scleroderma Trials And Research (EUSTAR) group was formed in June 2004. Aims and methods EUSTAR collects prospectively the Minimal Essential Data Set (MEDS) on all sequential patients fulfilling the American College of Rheumatology diagnostic criteria in participating centres. We aimed to characterise demographic, clinical and laboratory characteristics of disease presentation in SSc and analysed EUSTAR baseline visits. Results In April 2006, a total of 3656 patients (1349 with dcSSc and 2101 with lcSSc) were enrolled in 102 centres and 30 countries. 1330 individuals had autoantibodies against Scl70 and 1106 against anticentromere antibodies. 87% of patients were women. On multivariate analysis, scleroderma subsets (dcSSc vs lcSSc), antibody status and age at onset of Raynaud's phenomenon, but not gender, were found to be independently associated with the prevalence of organ manifestations. Autoantibody status in this analysis was more closely associated with clinical manifestations than were SSc subsets. Conclusion dcSSc and lcSSc subsets are associated with particular organ manifestations, but in this analysis the clinical distinction seemed to be superseded by an antibody?based classification in predicting some scleroderma complications. The EUSTAR MEDS database facilitates the analysis of clinical patterns in SSc, and contributes to the standardised assessment and monitoring of SSc internationally. PMID:17234652

  4. Risk of Ischaemic Heart Disease in Patients with Inflammatory Bowel Disease: Cohort Study Using the General Practice Research Database

    PubMed Central

    Close, Helen; Mason, James M.; Wilson, Douglas W.; Hungin, A. Pali S.; Jones, Roger; Rubin, Greg

    2015-01-01

    Objective Patients with inflammatory bowel disease (IBD) demonstrate an inflammatory response which bears some similarities to that seen in ischaemic heart disease (IHD). The nature of the association of IBD with IHD is uncertain. We aimed to define the extent and direction of that association. Design This retrospective cohort study examined records from patients aged ? 15 years with IBD from 1987–2009 (n = 19163) who were age and gender matched with patients without IBD (n = 75735) using the General Practice Research Database. The primary outcome was the hazard ratio for IHD. Results A higher proportion of IBD patients had a recorded diagnosis of IHD ever, 2220 (11.6%) compared with 6504 (8.6%) of controls. However, the majority (4494, 51.5%) developed IHD prior to IBD diagnosis (1404 (63.2%) of IBD cases and 3090 (47.5%) of controls). There was increased IHD incidence in the first year after IBD diagnosis. Mean age at IHD diagnosis was statistically similar across all IBD groups apart from for those with Ulcerative Colitis (UC) who were slightly younger at diagnosis of angina compared to controls (64.5y vs. 67.0y, p = 0.008) and coronary heart disease (65.7y vs.67.9y, p = 0.015). Of those developing IHD following IBD diagnosis, UC patients were at higher risk of IHD (unadjusted HR 1.3 (95% CI 1.1–1.5), p<0.001) or MI (unadjusted HR 1.4 (95% CI 1.1–1.6), p = 0.004). Conclusion Although IHD prevalence was higher in IBD patients, most IHD diagnoses predated the diagnosis of IBD. This implies a more complex relationship than previously proposed between the inflammatory responses associated with IHD and IBD, and alternative models should be considered. PMID:26461954

  5. Assisting science in the Former Soviet Union

    NASA Astrophysics Data System (ADS)

    Leath, Audrey T.

    The turmoil and economic hardships in the former Soviet Union have not bypassed its scientific community. Governments and scientists around the world bemoan the collapse of the Soviet science infrastructure and the potential loss of Soviet weapons scientists to untrustworthy nations. In joint research collaborations, many see both the chance to assist science in the former Soviet Union and a wellspring of potentially commercial technology.The biggest effort to date is a joint agreement among Russia, the European Community, Japan, and the United States to set up an International Science and Technology Center in Moscow. The center will act as a clearinghouse for proposals from the former Soviet Union to fund research for former weapons scientists. The member nations could support proposals either singularly or jointly. Although all the details have yet to be worked out, the United States has pledged $25 million to this effort so far.

  6. Trade Union Rights.

    ERIC Educational Resources Information Center

    Maier, Heribert; And Others

    1994-01-01

    Excerpts addresses from an international symposium regarding workers' education, human rights, labor standards and law, socioeconomic factors, trade unions, workers' rights, professionalism, and globalization. Includes a background paper, "Participation of Workers and Their Organizations in the Field of International Labour Standards and the…

  7. Trade Union Rights.

    ERIC Educational Resources Information Center

    Maier, Heribert; And Others

    1994-01-01

    Excerpts addresses from an international symposium regarding workers' education, human rights, labor standards and law, socioeconomic factors, trade unions, workers' rights, professionalism, and globalization. Includes a background paper, "Participation of Workers and Their Organizations in the Field of International Labour Standards and the…

  8. Facility Focus: Student Unions.

    ERIC Educational Resources Information Center

    College Planning & Management, 1999

    1999-01-01

    Describes four student union building designs that make students feel more comfortable in their surroundings. Examples show how design can inspire campus life and school spirit, enhance food service and increase the number of cash business customers, and provide a community feeling through the addition of multiservices. (GR)

  9. Growth in Employee Unions

    ERIC Educational Resources Information Center

    Grayson, E. C.

    1977-01-01

    A growth in organized school employee groups, particularly teacher groups, may require school boards to develop and maintain an affirmative employee relations program to identify and meet needs before they reach the crisis level and, therefore, prevent the issues from developing around which employee unions must justify their existence.…

  10. Marketing the College Union.

    ERIC Educational Resources Information Center

    Hoef, Ted; Howe, Nanci

    Theory underlying marketing in the public sector is presented in combination with specific examples of marketing strategies and techniques used in college unions and student activities programs across the country. The subject of marketing is discussed under six major subject headings: (1) why marketing? (2) analyzing marketing opportunities; (3)…

  11. Reflections on a decade of research by ASEAN dental faculties: analysis of publications from ISI-WOS databases from 2000 to 2009.

    PubMed

    Sirisinha, Stitaya; Koontongkaew, Sittichai; Phantumvanit, Prathip; Wittayawuttikul, Ruchareka

    2011-05-01

    This communication analyzed research publications in dentistry in the Institute of Scientific Information Web of Science databases of 10 dental faculties in the Association of South-East Asian Nations (ASEAN) from 2000 to 2009. The term used for the "all-document types" search was "Faculty of Dentistry/College of Dentistry." Abstracts presented at regional meetings were also included in the analysis. The Times Higher Education System QS World University Rankings showed that universities in the region fare poorly in world university rankings. Only the National University of Singapore and Nanyang Technological University appeared in the top 100 in 2009; 19 universities in the region, including Indonesia, Malaysia, the Philippines, Singapore, and Thailand, appeared in the top 500. Data from the databases showed that research publications by dental institutes in the region fall short of their Asian counterparts. Singapore and Thailand are the most active in dental research of the ASEAN countries. PMID:25426599

  12. New Roles for Teachers Unions? Reform Unionism in School Decentralization

    ERIC Educational Resources Information Center

    Donaldson, Morgaen L.; Mayer, Anysia P.; Cobb, Casey D.; LeChasseur, Kimberly; Welton, Anjale

    2013-01-01

    Of late, teachers unions have worked together with district management in new and notable ways. This paper examines the role of teachers unions in shaping the Together Initiative (TI), which seeks to increase autonomy and broaden decision making in urban schools in one northeastern state. In general, state-level union leaders have taken more…

  13. Teacher Unions and Parent Involvement. EPI Series on Teacher Unions.

    ERIC Educational Resources Information Center

    Haar, Charlene K.

    This booklet, part of the Education Policy Institute series about teacher union issues, clarifies the concept of parent involvement in educational reform, analyzing the treatment of parents in collective bargaining contracts between teacher unions and school boards and in union policy resolutions. Chapter 1 introduces the issue, offering an…

  14. Legalization of consensual unions in Latin America.

    PubMed

    Goldman, N; Pebley, A R

    1981-01-01

    In Latin America, socially sanctioned conjugal unions take 2 forms: legal marriage and consensual unions. While legal marriage is more prestigious, consensual unions offer practical advantages. An examination of the legalization of consensual unions in rural areas in Colombia, Peru, Costa Rica, and Mexico is undertaken using data from the 1969 Centro Latinoamericano de Demografia's (CELADE) comparative survey of fertility. The survey in each country is based on a self weighted sample of 2000-3000 women aged 15-49 living in areas with fewer than 20,000 inhabitants. The union histories addressed types of unions, duration, and age and date of onset and of termination. The samples consisted of 881 unions in Colombia, 646 in Costa Rica, 865 in Mexico, and 1009 in Peru. The risk of legalization was measured by life table procedures, using only single decrement values for comparisons among subgroups. Between 32-41% of the unions are consensual in the rural areas of these countries. With the exception of Peru, consensual unions are higher among 2nd and later unions than among 1st unions. As expected from previous studies, they are more prevalent among younger women, those without education and among non-Catholics or non-practicing Catholics. About 30% of the consensual unions become legalized in Colombia, Costa Rica, and Mexico, and in Peru the rate of conversion is about 50%. Less than 20% in Colombia and Peru remain intact for more than 25 years; about 25% are terminated within the 1st 2 years. The single decrement values suggest that in the absence of separation or death of a partner, almost 50% of the unions would eventually be legalized in Colombia, Costa Rica, and Mexico, about 65% in Peru. The probability of conversion is highest among women in their 1st union and in the 1st year. Only 2-8% of the women legalize higher order unions. Of the factors related to the probability of legalization, age is an important differential in Costa Rica, education in Mexico, and religious observance in Colombia, Costa Rica, and Peru. The occurrence of a pregnancy does not substantially increase the frequency of legalization. This may be due to the absence of social disapproval of illegitimate children. In all 4 countries, marriages preceded by a period of cohabitation were less likely to end in separation. The higher age at marriage for couples who lived together before marriage explains some of the greater stability. The results do not support the widely held assumption that legalization occurs to legitimize births. Education and age are factors that account for some difference in frequency. Because the analysis is restricted to rural areas, additional research is needed to illuminate relationships in urban areas. PMID:7348446

  15. The Development of Trade Unionism.

    ERIC Educational Resources Information Center

    Parker, Ronald W.

    1979-01-01

    Traces the growth and evolution of the British labor union movement, troubles between the national officials and the local shop stewards, class differences and conflict between the artisans and laborers, violence between unions, and eventual transition to peaceful constitutionalism. (MF)

  16. Health Science Audiovisuals in Online Databases. Part 2.

    ERIC Educational Resources Information Center

    Van Camp, Ann

    1982-01-01

    Identifies new databases and changes in existing databases from commercial and government sources which contain information on audiovisual instructional materials relevant to the health sciences. Locating directories of AV materials, relevant bibliographic utilities, and regional union catalogs are also discussed. A table lists databases…

  17. Database for propagation models

    NASA Technical Reports Server (NTRS)

    Kantak, Anil V.

    1991-01-01

    A propagation researcher or a systems engineer who intends to use the results of a propagation experiment is generally faced with various database tasks such as the selection of the computer software, the hardware, and the writing of the programs to pass the data through the models of interest. This task is repeated every time a new experiment is conducted or the same experiment is carried out at a different location generating different data. Thus the users of this data have to spend a considerable portion of their time learning how to implement the computer hardware and the software towards the desired end. This situation may be facilitated considerably if an easily accessible propagation database is created that has all the accepted (standardized) propagation phenomena models approved by the propagation research community. Also, the handling of data will become easier for the user. Such a database construction can only stimulate the growth of the propagation research it if is available to all the researchers, so that the results of the experiment conducted by one researcher can be examined independently by another, without different hardware and software being used. The database may be made flexible so that the researchers need not be confined only to the contents of the database. Another way in which the database may help the researchers is by the fact that they will not have to document the software and hardware tools used in their research since the propagation research community will know the database already. The following sections show a possible database construction, as well as properties of the database for the propagation research.

  18. College Union Facilities and Their Perceived Influence on Institutional Retention

    ERIC Educational Resources Information Center

    Tierno, Scott A.

    2013-01-01

    The College Union is a campus facility that is part of the campus ecology. It provides a place where all can feel a sense of inclusion, safety, involvement, and community. Through a comparative research approach I will present how both students and professional staff perceive the College Union, the programs that are part of the facility, and how…

  19. College Union Facilities and Their Perceived Influence on Institutional Retention

    ERIC Educational Resources Information Center

    Tierno, Scott A.

    2013-01-01

    The College Union is a campus facility that is part of the campus ecology. It provides a place where all can feel a sense of inclusion, safety, involvement, and community. Through a comparative research approach I will present how both students and professional staff perceive the College Union, the programs that are part of the facility, and how…

  20. Union Members Are Community Members

    ERIC Educational Resources Information Center

    Gray, David

    2013-01-01

    Unions serve their members' interests. But union members are also community members, and their interests go well beyond increasing pay and benefits. A local union president has found that his members are best served by participating in a community-wide coalition. Providing eyeglasses to needy students, promoting healthy eating, and increasing…

  1. English in the Union Hall.

    ERIC Educational Resources Information Center

    Trebble, Maggi; Wallace, David

    1982-01-01

    A course developed by a college in conjunction with a major union focused entirely on English as a means of becoming more active in the union, understanding the collective bargaining agreement, and defending union member rights. Program development, material development, and teaching methods are discussed. (MSE)

  2. Women and Trade Union Education.

    ERIC Educational Resources Information Center

    Holmes, Caroline; Jackson, Judith

    2000-01-01

    Many British unions are failing to attract women members. The General Federal of Trade Unions has begun a women's studies program, offering communication and confidence building, women's history, and other courses that are helping women become involved in union l leadership and decision making. (SK)

  3. From clinical data records to research: a database system for the study of clinical and functional indicators of chronic heart failure.

    PubMed

    Pinna, G D; Opasich, C; Massimo, S; Perinati, L; Cobelli, F; Tavazzi, L

    1997-01-01

    The identification of reliable clinical and functional indicators of Chronic Heart Failure (CHF) is currently a major research challenge for physicians dealing with this pathology. With the aim of providing an adequate infrastructure for this research, we have developed a Database System where all relevant information concerning CHF patients during follow-up can be efficiently recorded, monitored, extracted and easily transferred to commercial packages for data processing and statistical analysis. Patient clinical status is recorded every 6 months, whereas data from several laboratory investigations are recorded every 12 months. All complications or events between two successive controls are recorded too. Patients needing cardiac transplantation are entered in a transplantation waiting list. The Database is fully integrated into the Hospital Information System and meets the standards of the national database of CHF patients. It grows with the concurrent activity of several independent teams, all of which have access to complete and structured information for research purposes. A user-friendly procedure allows the export in a standard format (Microsoft Excel) of all patients' data pertaining to a selected set of controls and variables of interest. These data are used directly for analysis or sub-selections are performed by the investigator through a simple query language. Depending on the objectives and complexity of the research, different commercial statistical analysis packages are available, which are used by clinical investigators autonomously or with the aid of a statistician. This overall approach allows great autonomy of each user in extracting, manipulating and statistically analyzing data. The Database has been in use at the Heart Failure Unit of our Rehabilitation Center since October 1992 and 595 patients have been enrolled since then. Several studies based on these data have been performed and more than 120 scientific communications and 30 articles in national and international journals have been produced. Hence, this experience represents a successful example of how clinical data records can be efficiently and effectively linked to valuable clinical research. PMID:10179770

  4. Computer Based Learning in the Soviet Union--I.

    ERIC Educational Resources Information Center

    Rushby, N. J.

    This bibliography lists 86 references, most of which are annotated, to papers and journal articles on computer assisted learning (CAL) in the Soviet Union. Topics dealt with include problem solving models, decision strategies, programmed instruction, algorithms, simulation, educational games, databases, and testing. The references have been…

  5. The Process of Entering into Cohabiting Unions

    ERIC Educational Resources Information Center

    Sassler, Sharon

    2004-01-01

    Over one half of young adults have lived or will live with a partner before marriage. Many studies indicate that the majority of cohabitors plan to marry their partners, yet research examining relationship progression is rare. This article deciphers the processes underlying entrance into informal unions. Data are from 25 open-ended interviews with…

  6. Election Behavior and Union Representation Elections.

    ERIC Educational Resources Information Center

    Black, David

    1980-01-01

    Examines the National Labor Relations Board's policy on intervention in union representation elections prior to the "Shopping Kart" decision and as a result of the "General Knit" decision. The effect of a research study on the board's decision on when to intervene in elections is also discussed. (IRT)

  7. Biofuel Database

    National Institute of Standards and Technology Data Gateway

    Biofuel Database (Web, free access)   This database brings together structural, biological, and thermodynamic data for enzymes that are either in current use or are being considered for use in the production of biofuels.

  8. A spatial classification and database for management, research, and policy making: The Great Lakes aquatic habitat framework

    EPA Science Inventory

    Managing the world’s largest and complex freshwater ecosystem, the Laurentian Great Lakes, requires a spatially hierarchical basin-wide database of ecological and socioeconomic information that are comparable across the region. To meet such a need, we developed a hierarchi...

  9. A spatial classification and database for management, research, and policy making: The Great Lakes aquatic habitat framework

    EPA Science Inventory

    Managing the world’s largest and complex freshwater ecosystem, the Laurentian Great Lakes, requires a spatially hierarchical basin-wide database of ecological and socioeconomic information that are comparable across the region. To meet such a need, we developed a hierarchi...

  10. Working with Existing Databases

    PubMed Central

    Murphy, Melissa; Alavi, Karim; Maykel, Justin

    2013-01-01

    Outcomes research has established itself as an integral part of surgical research as physicians and hospitals are increasingly required to demonstrate attainment of performance markers and surgical safety indicators. Large-volume and clinical and administrative databases are used to study regional practice pattern variations, health care disparities, and resource utilization. Understanding the unique strengths and limitations of these large databases is critical to performing quality surgical outcomes research. In the current work, we review the currently available large-volume databases including selection processes, modes of analyses, data application, and limitations. PMID:24436641

  11. Ionic Liquids Database- (ILThermo)

    National Institute of Standards and Technology Data Gateway

    SRD 147 Ionic Liquids Database- (ILThermo) (Web, free access)   IUPAC Ionic Liquids Database, ILThermo, is a free web research tool that allows users worldwide to access an up-to-date data collection from the publications on experimental investigations of thermodynamic, and transport properties of ionic liquids as well as binary and ternary mixtures containing ionic liquids.

  12. Database Administrator

    ERIC Educational Resources Information Center

    Moore, Pam

    2010-01-01

    The Internet and electronic commerce (e-commerce) generate lots of data. Data must be stored, organized, and managed. Database administrators, or DBAs, work with database software to find ways to do this. They identify user needs, set up computer databases, and test systems. They ensure that systems perform as they should and add people to the…

  13. Database Administrator

    ERIC Educational Resources Information Center

    Moore, Pam

    2010-01-01

    The Internet and electronic commerce (e-commerce) generate lots of data. Data must be stored, organized, and managed. Database administrators, or DBAs, work with database software to find ways to do this. They identify user needs, set up computer databases, and test systems. They ensure that systems perform as they should and add people to the…

  14. Towards secondary use of heterogeneous radio-oncological data for retrospective clinical trials: service-oriented connection of a central research database with image analysis tools

    NASA Astrophysics Data System (ADS)

    Bougatf, Nina; Bendl, Rolf; Debus, Jürgen

    2015-03-01

    Our overall objective is the utilization of heterogeneous and distributed radio-oncological data in retrospective clinical trials. Previously, we have successfully introduced a central research database for collection of heterogeneous data from distributed systems. The next step is the integration of image analysis tools in the standard retrieval process. Hence, analyses for complex medical questions can be processed automatically and facilitated immensely. In radiation oncology recurrence analysis is a central approach for the evaluation of therapeutic concepts. However, various analysis steps have to be performed like image registration, dose transformation and dose statistics. In this paper we show the integration of image analysis tools in the standard retrieval process by connecting them with our central research database using a service-oriented approach. A concrete problem from recurrence analysis has been selected to prove our concept exemplarily. We implemented service-oriented data collection and analysis tools to use them in a central analysis platform, which is based on a work flow management system. An analysis work flow has been designed that, at first, identifies patients in the research database fulfilling the inclusion criteria. Then the relevant imaging data is collected. Finally the imaging data is analyzed automatically. After the successful work flow execution, the results are available for further evaluation by a physician. As a result, the central research database has been connected successfully with automatic data collection and image analysis tools and the feasibility of our service-oriented approach has been demonstrated. In conclusion, our approach will simplify retrospective clinical trials in our department in future.

  15. Nuclear Science References Database

    NASA Astrophysics Data System (ADS)

    Pritychenko, B.; B?ták, E.; Singh, B.; Totans, J.

    2014-06-01

    The Nuclear Science References (NSR) database together with its associated Web interface, is the world's only comprehensive source of easily accessible low- and intermediate-energy nuclear physics bibliographic information for more than 210,000 articles since the beginning of nuclear science. The weekly-updated NSR database provides essential support for nuclear data evaluation, compilation and research activities. The principles of the database and Web application development and maintenance are described. Examples of nuclear structure, reaction and decay applications are specifically included. The complete NSR database is freely available at the websites of the National Nuclear Data Center http://www.nndc.bnl.gov/nsr.

  16. Backing up DMF Databases

    NASA Technical Reports Server (NTRS)

    Cardo, Nicholas P.; Woodrow, Thomas (Technical Monitor)

    1994-01-01

    A complete backup of the Cray Data Migration Facility (DMF) databases should include the data migration databases, all media specific process' (MSP's) databases, and the journal file. The backup should be able to accomplished without impacting users or stopping DMF. The High Speed Processors group at the Numerical Aerodynamics Simulation (NAS) Facility at NASA Ames Research Center undertook the task of finding an effective and efficient way to backup all DMF databases. This has been accomplished by taking advantage of new features introduced in DMF 2.0 and adding a minor modification to the dmdaemon. This paper discusses the investigation and the changes necessary to implement these enhancements.

  17. NEUSE RIVER WATER QUALITY DATABASE

    EPA Science Inventory

    The Neuse River water quality database is a Microsoft Access application that includes multiple data tables and some associated queries. The database was developed by Prof. Jim Bowen's research group.

  18. Relationship effort, satisfaction, and stability: differences across union type.

    PubMed

    Shafer, Kevin; Jensen, Todd M; Larson, Jeffry H

    2014-04-01

    Relationship satisfaction and stability are two commonly studied outcomes in marriage and family research. Majority of studies address socio demographic variability and differences across union type in these outcomes. We extend this literature by addressing how the amount of effort one puts into their relationship is associated with stability and satisfaction. Specifically, we focus on how effort impacts these measures of quality in four union types: premarital cohabitation, first marriage, post-divorce cohabitation, and second marriage following divorce. Furthermore, we make union type comparisons in the strength of effort's association with satisfaction and stability. Using data from 8,006 respondents in the Relationship Evaluation Survey, our results show that effort was strongly and positively associated with satisfaction and stability in all four unions. Although effort is more strongly associated with satisfaction in first marriage than cohabiting relationships, no union type differences in the role of effort on stability were observed. Clinical and research implications of these findings are discussed. PMID:24320175

  19. Development of a database for prompt gamma-ray neutron activation analysis: Summary report of the third research coordination meeting

    SciTech Connect

    Lindstrom, Richard M.; Firestone, Richard B.; Pavi, ???

    2003-04-01

    The main discussions and conclusions from the Third Co-ordination Meeting on the Development of a Database for Prompt Gamma-ray Neutron Activation Analysis are summarized in this report. All results were reviewed in detail, and the final version of the TECDOC and the corresponding software were agreed upon and approved for preparation. Actions were formulated with the aim of completing the final version of the TECDOC and associated software by May 2003.

  20. FORT UNION DEEP

    SciTech Connect

    Lyle A. Johnson Jr.

    2002-09-01

    Coalbed methane (CBM) is currently the hottest area of energy development in the Rocky Mountain area. The Powder River Basin (PRB) is the largest CBM area in Wyoming and has attracted the majority of the attention because of its high permeability and relatively shallow depth. Other Wyoming coal regions are also being targeted for development, but most of these areas have lower permeability and deeper coal seams. This project consists of the development of a CBM stimulation system for deep coal resources and involves three work areas: (1) Well Placement, (2) Well Stimulation, and (3) Production Monitoring and Evaluation. The focus of this project is the Washakie Basin. Timberline Energy, Inc., the cosponsor, has a project area in southern Carbon County, Wyoming, and northern Moffat County, Colorado. The target coal is found near the top of the lower Fort Union formation. The well for this project, Evans No.1, was drilled to a depth of 2,700 ft. Three coal seams were encountered with sandstone and some interbedded shale between seams. Well logs indicated that the coal seams and the sandstone contained gas. For the testing, the upper seam at 2,000 ft was selected. The well, drilled and completed for this project, produced very little water and only occasional burps of methane. To enhance the well, a mild severity fracture was conducted to fracture the coal seam and not the adjacent sandstone. Fracturing data indicated a fracture half-length of 34 ft, a coal permeability of 0.2226 md, and permeability of 15.3 md. Following fracturing, the gas production rate stabilized at 10 Mscf/day within water production of 18 bpd. The Western Research Institute (WRI) CBM model was used to design a 14-day stimulation cycle followed by a 30-day production period. A maximum injection pressure of 1,200 psig to remain well below the fracture pressure was selected. Model predictions were 20 Mscf/day of air injection for 14 days, a one-day shut-in, then flowback. The predicted flowback was a four-fold increase over the prestimulation rate with production essentially returning to prestimulation rates after 30 days. The physical stimulation was conducted over a 14-day period. Problems with the stimulation injection resulted in a coal bed fire that was quickly quenched when production was resumed. The poststimulation, stabilized production was three to four times the prestimulation rate. The methane content was approximately 45% after one day and increased to 65% at the end of 30 days. The gas production rate was still two and one-half times the prestimulation rate at the end of the 30-day test period. The field results were a good match to the numerical simulator predictions. The physical stimulation did increase the production, but did not produce a commercial rate.

  1. FORT UNION DEEP

    SciTech Connect

    Lyle A. Johnson Jr.

    2002-03-01

    Coalbed methane (CBM) is currently the hottest area of energy development in the Rocky Mountain area. The Powder River Basin (PRB) is the largest CBM area in Wyoming and has attracted the majority of the attention because of its high permeability and relatively shallow depth. Other Wyoming coal regions are also being targeted for development, but most of these areas have lower permeability and deeper coal seams. This project consists of the development of a CBM stimulation system for deep coal resources and involves three work areas: (1) Well Placement, (2) Well Stimulation, and (3) Production Monitoring and Evaluation. The focus of this project is the Washakie Basin. Timberline Energy, Inc., the cosponsor, has a project area in southern Carbon County, Wyoming, and northern Moffat County, Colorado. The target coal is found near the top of the lower Fort Union formation. The well for this project, Evans No.1, was drilled to a depth of 2,700 ft. Three coal seams were encountered with sandstone and some interbedded shale between seams. Well logs indicated that the coal seams and the sandstone contained gas. For the testing, the upper seam at 2,000 ft was selected. The well, drilled and completed for this project, produced very little water and only occasional burps of methane. To enhance the well, a mild severity fracture was conducted to fracture the coal seam and not the adjacent sandstone. Fracturing data indicated a fracture half-length of 34 ft, a coal permeability of 0.2226 md, and permeability of 15.3 md. Following fracturing, the gas production rate stabilized at 10 Mscf/day within water production of 18 bpd. The Western Research Institute (WRI) CBM model was used to design a 14-day stimulation cycle followed by a 30-day production period. A maximum injection pressure of 1,200 psig to remain well below the fracture pressure was selected. Model predictions were 20 Mscf/day of air injection for 14 days, a one-day shut-in, then flowback. The predicted flowback was a four-fold increase over the prestimulation rate with production essentially returning to prestimulation rates after 30 days. The physical stimulation was conducted over a 14-day period. Problems with the stimulation injection resulted in a coal bed fire that was quickly quenched when production was resumed. The poststimulation, stabilized production was three to four times the prestimulation rate. The methane content was approximately 45% after one day and increased to 65% at the end of 30 days. The gas production rate was still two and one-half times the prestimulation rate at the end of the 30-day test period. The field results were a good match to the numerical simulator predictions. The physical stimulation did increase the production, but did not produce a commercial rate.

  2. From "School Correspondent" to Workplace Bargainer? The Changing Role of the School Union Representative

    ERIC Educational Resources Information Center

    Stevenson, Howard

    2005-01-01

    This paper draws on research in three English Midlands local education authorities to analyse the changing role of the teacher trade union representative in schools. It focuses on representatives of the largest teachers' union in England and Wales--the National Union of Teachers. The paper draws on mainstream industrial relations literature, and…

  3. Examining the Factors Resulting in Faculty Unionization at Three Ohio Community Colleges

    ERIC Educational Resources Information Center

    Stilson-Hart, Amy

    2009-01-01

    Unionization efforts on community college campuses have increased fivefold over the past decade, this research addressed issues relating to increased levels of faculty unionization on community college campuses in Ohio. The purpose of this quantitative study was to examine and describe what, if any, relationships exist among faculty union…

  4. Reconcilable Differences: Conflict and Collegiality in a Unionized Community College Environment

    ERIC Educational Resources Information Center

    Hartley, Matthew

    2010-01-01

    Faculty unions are a prominent, though a comparatively recent, feature of American higher education. Today, a vast majority of community colleges have a unionized faculty. A number of researchers in the 1970s speculated that the presence of unions signaled the end of collegial shared governance and that interactions between administrators and…

  5. Toward a standard reference database for computer-aided mammography

    NASA Astrophysics Data System (ADS)

    Oliveira, Júlia E. E.; Gueld, Mark O.; de A. Araújo, Arnaldo; Ott, Bastian; Deserno, Thomas M.

    2008-03-01

    Because of the lack of mammography databases with a large amount of codified images and identified characteristics like pathology, type of breast tissue, and abnormality, there is a problem for the development of robust systems for computer-aided diagnosis. Integrated to the Image Retrieval in Medical Applications (IRMA) project, we present an available mammography database developed from the union of: The Mammographic Image Analysis Society Digital Mammogram Database (MIAS), The Digital Database for Screening Mammography (DDSM), the Lawrence Livermore National Laboratory (LLNL), and routine images from the Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen. Using the IRMA code, standardized coding of tissue type, tumor staging, and lesion description was developed according to the American College of Radiology (ACR) tissue codes and the ACR breast imaging reporting and data system (BI-RADS). The import was done automatically using scripts for image download, file format conversion, file name, web page and information file browsing. Disregarding the resolution, this resulted in a total of 10,509 reference images, and 6,767 images are associated with an IRMA contour information feature file. In accordance to the respective license agreements, the database will be made freely available for research purposes, and may be used for image based evaluation campaigns such as the Cross Language Evaluation Forum (CLEF). We have also shown that it can be extended easily with further cases imported from a picture archiving and communication system (PACS).

  6. The Research Article as an Instrument of Active Learning for Teaching about Violence, Sexual Abuse, and Union Formation among Low-Income Families

    ERIC Educational Resources Information Center

    Purvin, Diane M.; Kain, Edward L.

    2005-01-01

    As noted by Goldsmid and Wilson a quarter of a century ago, a "curious gulf" exists between teaching and research in sociology. This article addresses this problem by suggesting ways in which a current research article from the American Sociological Review can be used in courses at three different levels of the undergraduate curriculum. The active…

  7. Databases for LDEF results

    NASA Technical Reports Server (NTRS)

    Bohnhoff-Hlavacek, Gail

    1992-01-01

    One of the objectives of the team supporting the LDEF Systems and Materials Special Investigative Groups is to develop databases of experimental findings. These databases identify the hardware flown, summarize results and conclusions, and provide a system for acknowledging investigators, tracing sources of data, and future design suggestions. To date, databases covering the optical experiments, and thermal control materials (chromic acid anodized aluminum, silverized Teflon blankets, and paints) have been developed at Boeing. We used the Filemaker Pro software, the database manager for the Macintosh computer produced by the Claris Corporation. It is a flat, text-retrievable database that provides access to the data via an intuitive user interface, without tedious programming. Though this software is available only for the Macintosh computer at this time, copies of the databases can be saved to a format that is readable on a personal computer as well. Further, the data can be exported to more powerful relational databases, capabilities, and use of the LDEF databases and describe how to get copies of the database for your own research.

  8. Union Density and Hospital Outcomes.

    PubMed

    Koys, Daniel J; Martin, Wm Marty; LaVan, Helen; Katz, Marsha

    2015-01-01

    The authors address the hospital outcomes of patient satisfaction, healthcare quality, and net income per bed. They define union density as the percentage of a hospital's employees who are in unions, healthcare quality as its 30-day acute myocardial infraction (AMI; heart attack) mortality rate, and patient satisfaction as its overall Hospital Consumer Assessment of Healthcare Providers and Systems score. Using a random sample of 84 union and 84 nonunion hospitals from across the United States, multiple regression analyses show that union density is negatively related to patient satisfaction. Union density is not related to healthcare quality as measured by the AMI mortality rate or to net income per bed. This implies that unions per se are not good or bad for hospitals. The authors suggest that it is better for hospital administrators to take a Balanced Scorecard approach and be concerned about employee satisfaction, patient satisfaction, healthcare quality, and net income. PMID:26652043

  9. Generalized Database Management System Support for Numeric Database Environments.

    ERIC Educational Resources Information Center

    Dominick, Wayne D.; Weathers, Peggy G.

    1982-01-01

    This overview of potential for utilizing database management systems (DBMS) within numeric database environments highlights: (1) major features, functions, and characteristics of DBMS; (2) applicability to numeric database environment needs and user needs; (3) current applications of DBMS technology; and (4) research-oriented and…

  10. Database Manager

    ERIC Educational Resources Information Center

    Martin, Andrew

    2010-01-01

    It is normal practice today for organizations to store large quantities of records of related information as computer-based files or databases. Purposeful information is retrieved by performing queries on the data sets. The purpose of DATABASE MANAGER is to communicate to students the method by which the computer performs these queries. This…

  11. Maize databases

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This chapter is a succinct overview of maize data held in the species-specific database MaizeGDB (the Maize Genomics and Genetics Database), and selected multi-species data repositories, such as Gramene/Ensembl Plants, Phytozome, UniProt and the National Center for Biotechnology Information (NCBI), ...

  12. Database Manager

    ERIC Educational Resources Information Center

    Martin, Andrew

    2010-01-01

    It is normal practice today for organizations to store large quantities of records of related information as computer-based files or databases. Purposeful information is retrieved by performing queries on the data sets. The purpose of DATABASE MANAGER is to communicate to students the method by which the computer performs these queries. This…

  13. The Construction of Professional Unionism by Teacher Union Leaders.

    ERIC Educational Resources Information Center

    Poole, Wendy L.

    Teacher unions are increasingly perceived as principal stakeholders in determining the overall effectiveness of school systems. This paper presents findings of a study that explored how teacher union leaders construct meaning about teachers' self-interests and education interests. Data were collected through interviews with 18 teacher union…

  14. Researchers under Pressure: A Comparative Study of New Forms of Producing, Advising and Transmitting Knowledge in Brazil and the European Union

    ERIC Educational Resources Information Center

    Bianchetti, Lucidio; Quartiero, Elisa Maria

    2010-01-01

    This article presents some data from the literature and opinions from responses to interviews with 74 Brazilian and 15 European researchers. They were questioned about their work and the consequences to their lives caused by the changes imposed by the Coordinating Agency for Improvement in Higher Education Personnel (CAPES) in Brazil and the…

  15. Populating a Control Point Database: A cooperative effort between the USGS, Grand Canyon Monitoring and Research Center and the Grand Canyon Youth Organization

    NASA Astrophysics Data System (ADS)

    Brown, K. M.; Fritzinger, C.; Wharton, E.

    2004-12-01

    The Grand Canyon Monitoring and Research Center measures the effects of Glen Canyon Dam operations on the resources along the Colorado River from Glen Canyon Dam to Lake Mead in support of the Grand Canyon Adaptive Management Program. Control points are integral for geo-referencing the myriad of data collected in the Grand Canyon including aerial photography, topographic and bathymetric data used for classification and change-detection analysis of physical, biologic and cultural resources. The survey department has compiled a list of 870 control points installed by various organizations needing to establish a consistent reference for data collected at field sites along the 240 mile stretch of Colorado River in the Grand Canyon. This list is the foundation for the Control Point Database established primarily for researchers, to locate control points and independently geo-reference collected field data. The database has the potential to be a valuable mapping tool for assisting researchers to easily locate a control point and reduce the occurrance of unknowingly installing new control points within close proximity of an existing control point. The database is missing photographs and accurate site description information. Current site descriptions do not accurately define the location of the point but refer to the project that used the point, or some other interesting fact associated with the point. The Grand Canyon Monitoring and Research Center (GCMRC) resolved this problem by turning the data collection effort into an educational exercise for the participants of the Grand Canyon Youth organization. Grand Canyon Youth is a non-profit organization providing experiential education for middle and high school aged youth. GCMRC and the Grand Canyon Youth formed a partnership where GCMRC provided the logistical support, equipment, and training to conduct the field work, and the Grand Canyon Youth provided the time and personnel to complete the field work. Two data collection efforts were conducted during the 2004 summer allowing 40 youth the opportunity to contribute valuable information to the Control Point Database. This information included: verification of point existence, photographs, accurate site descriptions concisely describing the location of the point, how to reach the point, the specific point location and detailed bearings to visible and obvious land marks. The youth learned to locate themselves and find the points using 1:1000 airphotos, write detailed site descriptions, take bearings with a compass, measure vertical and horizontal distances, and use a digital camera. The youth found information for 252 control points (29% of the total points).

  16. News Music: Here comes science that rocks Student trip: Two views of the future of CERN Classroom: Researchers can motivate pupils Appointment: AstraZeneca trust appoints new director Multimedia: Physics Education comes to YouTube Competition: Students compete in European Union Science Olympiad 2010 Physics roadshow: Pupils see wonders of physics

    NASA Astrophysics Data System (ADS)

    2010-07-01

    Music: Here comes science that rocks Student trip: Two views of the future of CERN Classroom: Researchers can motivate pupils Appointment: AstraZeneca trust appoints new director Multimedia: Physics Education comes to YouTube Competition: Students compete in European Union Science Olympiad 2010 Physics roadshow: Pupils see wonders of physics

  17. The Impact of Police Unions: Summary Report.

    ERIC Educational Resources Information Center

    Juris, Hervey A.; Feuille, Peter

    To assess the impact of police unionism on the operation and administration of police departments, in-depth field surveys of active police unions were conducted in the summer and fall of 1971 in 22 cities where police unions were active. In the summary report the development of police unions is discussed, and the sources and dimensions of union…

  18. Teacher Unionization in School Governance

    ERIC Educational Resources Information Center

    Jacoby, Dan

    2011-01-01

    The role of unions in school governance is reviewed to note that labor operates in a larger context of principal-agent relationships. As agents for teachers, unions articulate the concerns that must be addressed if teachers are to be successfully enlisted in the struggle to reduce achievement gaps among at-risk students. Transcending industrial…

  19. Unions: Bread, Butter & Basic Skills.

    ERIC Educational Resources Information Center

    BCEL Newsletter for the Business Community, 1987

    1987-01-01

    Unions are natural providers of basic skills instruction. They are in daily workplace contact with their membership, are trusted to work on members' behalf, and speak the language of the worker. Unions are trying to address the needs of illiterate workers through collective bargaining arrangements in which employers contribute a percentage of…

  20. College/Labor Union Cooperation

    ERIC Educational Resources Information Center

    Abbott, William

    1977-01-01

    A survey of 1,054 institutions by the AACJC Service Center for Community College-Labor Union Cooperation concluded that while substantial joint undertakings exist between unions and community colleges, in many cases labor and community colleges are waiting for the other party to make the first move. (JG)

  1. Professional Employees Turn to Unions

    ERIC Educational Resources Information Center

    Chamot, Dennis

    1976-01-01

    White-collar and professional employees are increasingly turning to unions to combat their loss of independence as employees of large organizations. Managers should realize that they and professional employees have different viewpoints about job situations and that the current trend toward white-collar unionism is apt to continue. (JG)

  2. Bibliographic Databases Outside of the United States.

    ERIC Educational Resources Information Center

    McGinn, Thomas P.; And Others

    1988-01-01

    Eight articles describe the development, content, and structure of databases outside of the United States. Features discussed include library involvement, authority control, shared cataloging services, union catalogs, thesauri, abstracts, and distribution methods. Countries and areas represented are Latin America, Australia, the United Kingdom,…

  3. A Regional Bibliographic Database on Videodisc.

    ERIC Educational Resources Information Center

    Freund, Alfred L.

    1985-01-01

    Provides description of the initial creation of a regional union catalog containing 600,000 unique titles and 1.8 million physical items, the conversion of this database to interactive laserdisc, and the resultant advantages. Updates, costs, problems, and the application of laserdisc technology are discussed. (EJS)

  4. Trade Unions and the Economics Curriculum.

    ERIC Educational Resources Information Center

    Veale, Sarah

    1987-01-01

    Contends that a realistic approach to teaching economics requires learning about trade unions. Presents a role play of a trade union meeting that helps students think about how trade unions tackle problems. (BSR)

  5. BIOMARKERS DATABASE

    EPA Science Inventory

    This database was developed by assembling and evaluating the literature relevant to human biomarkers. It catalogues and evaluates the usefulness of biomarkers of exposure, susceptibility and effect which may be relevant for a longitudinal cohort study. In addition to describing ...

  6. VAMDC FP7 project and STARK-B database: C II Stark broadening parameters for white dwarf atmospheres research

    SciTech Connect

    Larbi-Terzi, Neila; Ben Nessib, Nebil; Sahal-Brechot, Sylvie; Dimitrijevic, Milan S.

    2010-11-23

    Stark broadening parameters of C II lines were determined within 3s-np spectral series within the semiclassical perturbation method. The atomic energy levels needed for calculations were taken from TOPBASE as well as the oscillator strengths, calculated additionally using the Coulomb approximation (the method of Bates and Damgaard). The both results were compared and the disagreement is found only in one case where the configuration mixing allows a forbidden transition to a close perturbing energy level. Calculations were performed for plasma conditions relevant for atmospheres of DQ white dwarfs and for a new type of white dwarfs, with surface composed mostly of carbon, discovered in 2007 by Dufour et al.. The aim of this work is to provide accurate C II Stark broadening data, which are crucial for this type of white dwarf atmosphere modellisation. Obtained results will be included in STARK-B database (http://stark-b.obspm.fr/), entering in the FP7 project of European Virtual Atomic and Molecular Data Center VAMDC aiming at building an interoperable e-Infrastructure for the exchange of atomic and molecular data (http://www.vamdc.org/).

  7. Food traceability systems in China: The current status of and future perspectives on food supply chain databases, legal support, and technological research and support for food safety regulation.

    PubMed

    Tang, Qi; Li, Jiajia; Sun, Mei; Lv, Jun; Gai, Ruoyan; Mei, Lin; Xu, Lingzhong

    2015-02-01

    Over the past few decades, the field of food security has witnessed numerous problems and incidents that have garnered public attention. Given this serious situation, the food traceability system (FTS) has become part of the expanding food safety continuum to reduce the risk of food safety problems. This article reviews a great deal of the related literature and results from previous studies of FTS to corroborate this contention. This article describes the development and benefits of FTS in developed countries like the United States of America (USA), Japan, and some European countries. Problems with existing FTS in China are noted, including a lack of a complete database, inadequate laws and regulations, and lagging technological research into FTS. This article puts forward several suggestions for the future, including improvement of information websites, clarification of regulatory responsibilities, and promotion of technological research. PMID:25787905

  8. From Telecommunications to Networking: The MELVYL Online Union Catalog and the Development of Intercampus Networks at the University of California.

    ERIC Educational Resources Information Center

    Lynch, Clifford A.

    1989-01-01

    Reviews the history of the network that supports the MELVYL online union catalog, describes current technological and policy issues, and discusses the role the network plays in integrating local automation, the union catalog, access to resource databases, and other initiatives. Sidebars by Mark Needleman discuss the TCP/IP protocol suite, internet…

  9. From Telecommunications to Networking: The MELVYL Online Union Catalog and the Development of Intercampus Networks at the University of California.

    ERIC Educational Resources Information Center

    Lynch, Clifford A.

    1989-01-01

    Reviews the history of the network that supports the MELVYL online union catalog, describes current technological and policy issues, and discusses the role the network plays in integrating local automation, the union catalog, access to resource databases, and other initiatives. Sidebars by Mark Needleman discuss the TCP/IP protocol suite, internet…

  10. Information Access Company Confirms Writers' Rights Issue in Database Marketing.

    ERIC Educational Resources Information Center

    Wachsberger, Ken

    1995-01-01

    Discusses licensing agreements and royalties to writers for the sale of articles from online databases. CARL Corporation is working with the National Writers' Union to devise a transaction-based method of paying royalty fees to authors whose articles are used through UnCover; this agreement could provide a model for use by all database services.…

  11. Information Access Company Confirms Writers' Rights Issue in Database Marketing.

    ERIC Educational Resources Information Center

    Wachsberger, Ken

    1995-01-01

    Discusses licensing agreements and royalties to writers for the sale of articles from online databases. CARL Corporation is working with the National Writers' Union to devise a transaction-based method of paying royalty fees to authors whose articles are used through UnCover; this agreement could provide a model for use by all database services.…

  12. Combined effect of donor and recipient risk on outcome after liver transplantation: Research of the Eurotransplant database.

    PubMed

    Blok, Joris J; Putter, Hein; Rogiers, Xavier; van Hoek, Bart; Samuel, Undine; Ringers, Jan; Braat, Andries E

    2015-12-01

    Recently the Eurotransplant donor risk index (ET-DRI) was published, a model based on data from the Eurotransplant database that can be used for risk indication of liver donors within the Eurotransplant region. Because outcome after liver transplantation (LT) depends both on donor and recipient risk factors, a combined donor-recipient model (DRM) would give a more complete picture of the overall risk involved. All liver transplants in adult recipients from January 1, 2008 to December 31, 2010 in the Eurotransplant region were included. Risk factors in donors and recipients for failure-free (retransplant free) survival were analyzed in univariate and multivariate analyses. A simplified recipient risk index (sRRI) was constructed using all available recipient factors. A total of 4466 liver transplants were analyzed. Median donor risk index and ET-DRI were 1.78 and 1.91, respectively. The ET-DRI was validated in this new cohort (P < 0.001; concordance index [c-index], 0.59). After construction of a simplified recipient risk index of significant recipient factors, Cox regression analysis showed that the combination ET-DRI and sRRI into a new DRM gave the highest predictive value (P < 0.001; c-index, 0.62). The combined model of ET-DRI and sRRI gave a significant prediction of outcome after orthotopic LT in the Eurotransplant region, better than the ET-DRI alone. This DRM has potential in comparing data in the literature and correcting for sickness/physical condition of transplant recipients. It is a first step toward benchmarking of graft survival in the Eurotransplant region. Liver Transpl 21:1486-1493, 2015. © 2015 AASLD. PMID:26289765

  13. Research opportunities using administrative databases and existing surveys for new knowledge in occupational health and safety in Canada, Quebec, Ontario and British Columbia.

    PubMed

    Smith, Peter M; Stock, Susan R; McLeod, Christopher B; Koehoorn, Mieke; Marchand, Alain; Mustard, Cameron A

    2010-01-01

    In Canada, many datasets are initially collected for purposes other than occupational health and safety (OHS) research. These include administrative health care billing records, pharmaceutical records, vital statistics, provincial cancer registries and workers' compensation claims data. In addition, many national and provincial health surveys, while not focused specifically on occupational health and safety, collect data on the health status and health determinants of populations, and such data can be used for investigating OHS issues among Canadian workers. This paper provides examples of the use of administrative and survey data for OHS research projects from the provinces of Quebec, Ontario and British Columbia to illustrate the potential of such data. These three provinces have a long history of using administrative and survey data for OHS research and have developed capacity in this regard for improving access to data, for linkage of records across databases and for developing methods to answer OHS questions. As research using these data sources expands, a consistent understanding within the work and health research community must be forged concerning the strengths and limitations of these data resources and their comparability. PMID:20629447

  14. Giving raw data a chance to talk: a demonstration of exploratory visual analytics with a pediatric research database using Microsoft Live Labs Pivot to promote cohort discovery, research, and quality assessment.

    PubMed

    Viangteeravat, Teeradache; Nagisetty, Naga Satya V Rao

    2014-01-01

    Secondary use of large and open data sets provides researchers with an opportunity to address high-impact questions that would otherwise be prohibitively expensive and time consuming to study. Despite the availability of data, generating hypotheses from huge data sets is often challenging, and the lack of complex analysis of data might lead to weak hypotheses. To overcome these issues and to assist researchers in building hypotheses from raw data, we are working on a visual and analytical platform called PRD Pivot. PRD Pivot is a de-identified pediatric research database designed to make secondary use of rich data sources, such as the electronic health record (EHR). The development of visual analytics using Microsoft Live Labs Pivot makes the process of data elaboration, information gathering, knowledge generation, and complex information exploration transparent to tool users and provides researchers with the ability to sort and filter by various criteria, which can lead to strong, novel hypotheses. PMID:24808811

  15. Hybrid knowledge- and databases

    SciTech Connect

    Taylor, M.

    1996-12-31

    In the modern era, databases have been created spanning many domains. However, these databases do not contain general knowledge about their respective domains. For example, whereas a medical database could contain an entry for a patient with some medical disorder, it would not normally contain taxonomic information about medical disorders, known causal agents, symptoms, etc. Collections of this sort of general information are usually called knowledge bases and powerful tools have been developed for querying these collections in complex and flexible ways. The research described in this abstract aims to develop methodologies for merging existing databases with knowledge bases, so that the power and flexibility of knowledge base technology can be applied to existing collections of data.

  16. Nuclear Science References Database

    SciTech Connect

    Pritychenko, B.; Běták, E.; Singh, B.; Totans, J.

    2014-06-15

    The Nuclear Science References (NSR) database together with its associated Web interface, is the world's only comprehensive source of easily accessible low- and intermediate-energy nuclear physics bibliographic information for more than 210,000 articles since the beginning of nuclear science. The weekly-updated NSR database provides essential support for nuclear data evaluation, compilation and research activities. The principles of the database and Web application development and maintenance are described. Examples of nuclear structure, reaction and decay applications are specifically included. The complete NSR database is freely available at the websites of the National Nuclear Data Center (http://www.nndc.bnl.gov/nsr) and the International Atomic Energy Agency (http://www-nds.iaea.org/nsr)

  17. Djeen (Database for Joomla!’s Extensible Engine): a research information management system for flexible multi-technology project administration

    PubMed Central

    2013-01-01

    Background With the advance of post-genomic technologies, the need for tools to manage large scale data in biology becomes more pressing. This involves annotating and storing data securely, as well as granting permissions flexibly with several technologies (all array types, flow cytometry, proteomics) for collaborative work and data sharing. This task is not easily achieved with most systems available today. Findings We developed Djeen (Database for Joomla!’s Extensible Engine), a new Research Information Management System (RIMS) for collaborative projects. Djeen is a user-friendly application, designed to streamline data storage and annotation collaboratively. Its database model, kept simple, is compliant with most technologies and allows storing and managing of heterogeneous data with the same system. Advanced permissions are managed through different roles. Templates allow Minimum Information (MI) compliance. Conclusion Djeen allows managing project associated with heterogeneous data types while enforcing annotation integrity and minimum information. Projects are managed within a hierarchy and user permissions are finely-grained for each project, user and group. Djeen Component source code (version 1.5.1) and installation documentation are available under CeCILL license from http://sourceforge.net/projects/djeen/files and supplementary material. PMID:23742665

  18. New Perspectives of "old" Data Sources: the Dataset of Long-Term Research Watersheds in the Former Soviet Union for the Task of Hydrological Models Development, Verification and Comparison

    NASA Astrophysics Data System (ADS)

    Lebedeva, L.; Semenova, O.

    2013-12-01

    Lack of detailed process-oriented observational data is often claimed as one of the major obstacle for further advance of hydrological process understanding and development of deterministic models that do not rely on calibration. New sources of hydrological information (satellites, radars etc.) have the perspectives for the future but can not completely replace conventional and experimental observations at the moment. Long-term data-rich research catchments remain valuable if not the only source of information for development, verification, regionalization and comparison of different hydrological and environmental models. There existed the set of more than 20 such basins that were operated according to single observational program from the 1930-1950th to 1990th in the former Soviet Union. Research basins, so called water-balance stations, covered all main climatic and landscape zones such as taiga, forest-steppe, steppe, desert, mountains and permafrost regions. Each station conducted broad range of standard, special and experimental hydrometeorological field studies including spatially distributed meteorological observations, soil and snow variable states, measurements of the groundwater levels, hydrochemistry, evapotranspiration, discharges in several, often nested, slope- and small-scale watersheds, etc. The data were accompanied by the descriptions of observational techniques and landscapes allowing linking natural conditions with dominant hydrological processes. Each station is representative for larger area and the results of local studies could be transferred to other basins in similar conditions. Till recently the data existed only in hard copies in Russian language therefore they are not enough explored yet. We are currently digitizing main part of the observational and supportive materials and make it available for any scientific purpose via website http://hydrograph-model.ru/. We propose to hydrological community to use the data for comprehensive intercomparison studies of our models and their modules to reject inadequate algorithms and advance our process understanding and modeling efforts in different environments.

  19. WMC Database Evaluation. Case Study Report

    SciTech Connect

    Palounek, Andrea P. T

    2015-10-29

    The WMC Database is ultimately envisioned to hold a collection of experimental data, design information, and information from computational models. This project was a first attempt at using the Database to access experimental data and extract information from it. This evaluation shows that the Database concept is sound and robust, and that the Database, once fully populated, should remain eminently usable for future researchers.

  20. AGSO 1993: Yearbook of the Australian Geological Survey Organisation. Geoscientific research and database development for the year 1 July 1992 to 30 June 1993

    NASA Astrophysics Data System (ADS)

    The Australian Geological Survey Organization (AGSO) has a mission to build a vigorous, client driven national geoscientific mapping effort to encourage economically and environmentally sustainable management of Australian's mineral, energy, soil, and water resources. The 1992-93 yearbook focuses on: (1) report by the Mineral and Environmental Group which is focused on the Richard Review that emphasized on national mapping through the national Geoscience Mapping Accord; (2) report by the Petroleum and Marine Geoscience Group which consists of a comprehensive evaluation of the Continental Margins Program (provides regional geoscience data) and the Richard Review that indicates AGSO's general program direction over the preceding years; (3) database coordination and research (operate, develop, and implement AGSO information technology strategy); and (4) program delivery which provides cartographic products and related services in support to the AGSO's program objectives.

  1. Secure analysis of distributed chemical databases without data integration.

    PubMed

    Karr, Alan F; Feng, Jun; Lin, Xiaodong; Sanil, Ashish P; Young, S Stanley; Reiter, Jerome P

    2005-01-01

    We present a method for performing statistically valid linear regressions on the union of distributed chemical databases that preserves confidentiality of those databases. The method employs secure multi-party computation to share local sufficient statistics necessary to compute least squares estimators of regression coefficients, error variances and other quantities of interest. We illustrate our method with an example containing four companies' rather different databases. PMID:16267693

  2. Biological Databases for Behavioral Neurobiology

    PubMed Central

    Baker, Erich J.

    2014-01-01

    Databases are, at their core, abstractions of data and their intentionally derived relationships. They serve as a central organizing metaphor and repository, supporting or augmenting nearly all bioinformatics. Behavioral domains provide a unique stage for contemporary databases, as research in this area spans diverse data types, locations, and data relationships. This chapter provides foundational information on the diversity and prevalence of databases, how data structures support the various needs of behavioral neuroscience analysis and interpretation. The focus is on the classes of databases, data curation, and advanced applications in bioinformatics using examples largely drawn from research efforts in behavioral neuroscience. PMID:23195119

  3. Epilepsy informatics and an ontology-driven infrastructure for large database research and patient care in epilepsy

    PubMed Central

    Sahoo, Satya S.; Zhang, Guo-Qiang; Lhatoo, Samden D.

    2013-01-01

    Summary The epilepsy community increasingly recognizes the need for a modern classification system that can also be easily integrated with effective informatics tools. The 2010 reports by the United States President's Council of Advisors on Science and Technology (PCAST) identified informatics as a critical resource to improve quality of patient care, drive clinical research, and reduce the cost of health services. An effective informatics infrastructure for epilepsy, which is underpinned by a formal knowledge model or ontology, can leverage an ever increasing amount of multimodal data to improve (1) clinical decision support, (2) access to information for patients and their families, (3) easier data sharing, and (4) accelerate secondary use of clinical data. Modeling the recommendations of the International League Against Epilepsy (ILAE) classification system in the form of an epilepsy domain ontology is essential for consistent use of terminology in a variety of applications, including electronic health records systems and clinical applications. In this review, we discuss the data management issues in epilepsy and explore the benefits of an ontology-driven informatics infrastructure and its role in adoption of a “data-driven” paradigm in epilepsy research. PMID:23647220

  4. 32 CFR 643.116 - Credit unions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 4 2013-07-01 2013-07-01 false Credit unions. 643.116 Section 643.116 National... Additional Authority of Commanders § 643.116 Credit unions. The establishment of credit unions on Army... buildings, without charge for rent or services, to any credit union organized under State law or to...

  5. 32 CFR 643.116 - Credit unions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Credit unions. 643.116 Section 643.116 National... Additional Authority of Commanders § 643.116 Credit unions. The establishment of credit unions on Army... buildings, without charge for rent or services, to any credit union organized under State law or to...

  6. 32 CFR 643.116 - Credit unions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 4 2012-07-01 2011-07-01 true Credit unions. 643.116 Section 643.116 National... Additional Authority of Commanders § 643.116 Credit unions. The establishment of credit unions on Army... buildings, without charge for rent or services, to any credit union organized under State law or to...

  7. 32 CFR 643.116 - Credit unions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 4 2014-07-01 2013-07-01 true Credit unions. 643.116 Section 643.116 National... Additional Authority of Commanders § 643.116 Credit unions. The establishment of credit unions on Army... buildings, without charge for rent or services, to any credit union organized under State law or to...

  8. 32 CFR 643.116 - Credit unions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 4 2011-07-01 2011-07-01 false Credit unions. 643.116 Section 643.116 National... Additional Authority of Commanders § 643.116 Credit unions. The establishment of credit unions on Army... buildings, without charge for rent or services, to any credit union organized under State law or to...

  9. 75 FR 60651 - Corporate Credit Unions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-01

    ... From the Federal Register Online via the Government Publishing Office NATIONAL CREDIT UNION ADMINISTRATION 12 CFR Part 704 RIN 3133-AD80 Corporate Credit Unions AGENCY: National Credit Union Administration... process for chartering corporate federal credit unions. DATES: Comments must be received on or...

  10. Union certification elections in nursing care facilities.

    PubMed

    Palthe, Jennifer; Deshpande, Satish P

    2003-01-01

    This empirical study examines 387 union certification elections conducted by the National Labor Relations Board in nursing care facilities (North American Industry Classification System 623) from January 1999 to December 2001. Unions won 60% of the elections. Service Employees International Union was involved in 42% of the elections. Bargaining unit size significantly impacted union victory. Unions had a better probability of winning elections in the northeast and midwest than in the south. Unlike other industries, American Federation of Labor-Congress of Industrial Organizations affiliated unions did not suffer a big labor image in nursing care facilities. Implications for union organizers and administrators of nursing care facilities are discussed. PMID:14672442

  11. Drinking Water Database

    NASA Technical Reports Server (NTRS)

    Murray, ShaTerea R.

    2004-01-01

    This summer I had the opportunity to work in the Environmental Management Office (EMO) under the Chemical Sampling and Analysis Team or CS&AT. This team s mission is to support Glenn Research Center (GRC) and EM0 by providing chemical sampling and analysis services and expert consulting. Services include sampling and chemical analysis of water, soil, fbels, oils, paint, insulation materials, etc. One of this team s major projects is the Drinking Water Project. This is a project that is done on Glenn s water coolers and ten percent of its sink every two years. For the past two summers an intern had been putting together a database for this team to record the test they had perform. She had successfully created a database but hadn't worked out all the quirks. So this summer William Wilder (an intern from Cleveland State University) and I worked together to perfect her database. We began be finding out exactly what every member of the team thought about the database and what they would change if any. After collecting this data we both had to take some courses in Microsoft Access in order to fix the problems. Next we began looking at what exactly how the database worked from the outside inward. Then we began trying to change the database but we quickly found out that this would be virtually impossible.

  12. A patient database application for Hereditary Deafness Epidemiology and Clinical Research (H.E.A.R.): an effort for standardization in multiple languages.

    PubMed

    Pfister, Markus; Akyildiz, Serdar; Gunhan, Ovunc; Maassen, Marcus; Rodriguez, Jorge Jesus; Zenner, Hans-Peter; Apaydin, Fazil

    2003-02-01

    One of the most challenging and neglected issues in medicine is the effective recording of the data obtained from the patients. The "European Work Group on the Genetics of Hearing Impairment," which has been working since 1996, proposed a few questionnaires to collect data regarding the phenotype, ENT findings, audiological examination findings and other special investigations. In this study, a computerized patient database application named "Izmir H.E.A.R version 1.0," written in Delphi 4.0 for Windows for recording the patients with hearing problems, is presented. The application consists of a modular form, including information about identity, genetic condition, proband query, audiology and vestibular tests, phenotype, pedigree and special examinations, which allows data entry on all these issues. It has been developed by using the guidelines of Hereditary Deafness Epidemiology and Clinical Research (H.E.A.R.) and by the experience gained within the last 10 years by the authors. The target population of the program is the ENT clinicians, audiologists, epidemiologists, geneticists and researchers in the field. The main idea is to create a program serving the needs of both the daily routine work and research purposes and to distribute this program to the above-mentioned specialists, to encourage them to try the first version and to find a standard and/or better way to collect data. For this reason, the program aims to be multilingual, and the currently available languages are English, German, Spanish and Turkish. PMID:12582784

  13. Databases and data mining

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Over the course of the past decade, the breadth of information that is made available through online resources for plant biology has increased astronomically, as have the interconnectedness among databases, online tools, and methods of data acquisition and analysis. For maize researchers, the numbe...

  14. Enzyme databases.

    PubMed

    Schomburg, Dietmar; Schomburg, Ida

    2010-01-01

    Enzymes are catalysts for the chemical reactions in the metabolism of all organisms and play a key role in the regulation of metabolic steps within the cells, as drug targets, and in a wide range of biotechnological applications. With respect to reaction type, they are grouped into six classes, namely oxidoreductases, transferases, hydrolases, lyases, and ligases. EC-Numbers are assigned by the IUBMB. Enzyme functional databases cover a wide range of properties and functions, such as occurrence, kinetics of enzyme-catalyzed reactions, structure, or metabolic function. BRENDA stores a large variety of different data for all classified enzymes whereas KEGG, MEROPS, MetaCyc, REBASE, CAzy, ESTHER, PeroxiBase, and KinBase specialize in either certain aspects of enzyme function or specific enzyme classes, organisms, or metabolic pathways. Databases covering enzyme nomenclature are ExplorEnz, SIB-ENZYME, and IntEnz. PMID:20221916

  15. Sexual Frequency and the Stability of Marital and Cohabiting Unions

    ERIC Educational Resources Information Center

    Yabiku, Scott T.; Gager, Constance T.

    2009-01-01

    Prior research found that lower sexual frequency and satisfaction were associated with higher rates of divorce, but little research had examined the role of sexual activity in the dissolution of cohabiting unions. We drew upon social exchange theory to hypothesize why sexual frequency is more important in cohabitation: (a) cohabitors' lower costs…

  16. USGS Biologist Elected Fellow of the American Ornithologists' Union

    USGS Multimedia Gallery

    Dr. Gary Krapu, U.S. Geological Survey scientist and Dickey County, N.D. native, was recently elected Fellow of the American Ornithologists' Union for his exceptional contributions to ornithology through research, conservation efforts, and education.  Krapu, a wildlife research biologist at th...

  17. The Definition of a Prolonged Intensive Care Unit Stay for Spontaneous Intracerebral Hemorrhage Patients: An Application with National Health Insurance Research Database

    PubMed Central

    Chan, Chien-Lung; Ting, Hsien-Wei; Huang, Hsin-Tsung

    2014-01-01

    Introduction. Length of stay (LOS) in the intensive care unit (ICU) of spontaneous intracerebral hemorrhage (sICH) patients is one of the most important issues. The disease severity, psychosocial factors, and institutional factors will influence the length of ICU stay. This study is used in the Taiwan National Health Insurance Research Database (NHIRD) to define the threshold of a prolonged ICU stay in sICH patients. Methods. This research collected the demographic data of sICH patients in the NHIRD from 2005 to 2009. The threshold of prolonged ICU stay was calculated using change point analysis. Results. There were 1599 sICH patients included. A prolonged ICU stay was defined as being equal to or longer than 10 days. There were 436 prolonged ICU stay cases and 1163 nonprolonged cases. Conclusion. This study showed that the threshold of a prolonged ICU stay is a good indicator of hospital utilization in ICH patients. Different hospitals have their own different care strategies that can be identified with a prolonged ICU stay. This indicator can be improved using quality control methods such as complications prevention and efficiency of ICU bed management. Patients' stay in ICUs and in hospitals will be shorter if integrated care systems are established. PMID:25126579

  18. Full-Text Databases in Medicine.

    ERIC Educational Resources Information Center

    Sievert, MaryEllen C.; And Others

    1995-01-01

    Describes types of full-text databases in medicine; discusses features for searching full-text journal databases available through online vendors; reviews research on full-text databases in medicine; and describes the MEDLINE/Full-Text Research Project at the University of Missouri (Columbia) which investigated precision, recall, and relevancy.…

  19. The Union Recreation Area. College Unions at Work.

    ERIC Educational Resources Information Center

    Stevens, George F.

    Within the context of college union programs, the recreational games of bowling, billiards, table tennis, and some table games are discussed, including their history, facilities, and operation. Specific duties and responsibilities of the Recreation Area Manager are outlined, as are counter personnel and procedures, and maintenance personnel and…

  20. The DIPPR® databases

    NASA Astrophysics Data System (ADS)

    Thomson, G. H.

    1996-01-01

    The Design Institute for Physical Property Data® (DIPPR), one of the Sponsored Research groups of the American Institute of Chemical Engineers (AIChE), has been in existence for 15 years and has supported a total of 14 projects, some completed, some ongoing. Four of these projects are “database” projects for which the primary product is a database of carefully evaluated property data. These projects are Data Compilation; Evaluated Data on Mixtures; Environmental, Safety, and Health Data Compilation; and Difusivities and Thermal Properties of Polymer Solutions. This paper lists the existing DIPPR projects; discusses DIPPR's structure and modes of dissemination of results; describes DIPPR's supporters and its unique characteristics; and finally, discusses the origin, nature, and content of the four database projects.

  1. ARTI Refrigerant Database

    SciTech Connect

    Calm, J.M.

    1992-04-30

    The Refrigerant Database consolidates and facilitates access to information to assist industry in developing equipment using alternative refrigerants. The underlying purpose is to accelerate phase out of chemical compounds of environmental concern. The database provides bibliographic citations and abstracts for publications that may be useful in research and design of air- conditioning and refrigeration equipment. The complete documents are not included, though some may be added at a later date. The database identifies sources of specific information on R-32, R-123, R-124, R- 125, R-134a, R-141b, R142b, R-143a, R-152a, R-290 (propane), R-717 (ammonia), ethers, and others as well as azeotropic and zeotropic blends of these fluids. It addresses polyalkylene glycol (PAG), ester, and other lubricants. It also references documents addressing compatibility of refrigerants and lubricants with metals, plastics, elastomers, motor insulation, and other materials used in refrigerant circuits.

  2. Mouse genome database 2016

    PubMed Central

    Bult, Carol J.; Eppig, Janan T.; Blake, Judith A.; Kadin, James A.; Richardson, Joel E.

    2016-01-01

    The Mouse Genome Database (MGD; http://www.informatics.jax.org) is the primary community model organism database for the laboratory mouse and serves as the source for key biological reference data related to mouse genes, gene functions, phenotypes and disease models with a strong emphasis on the relationship of these data to human biology and disease. As the cost of genome-scale sequencing continues to decrease and new technologies for genome editing become widely adopted, the laboratory mouse is more important than ever as a model system for understanding the biological significance of human genetic variation and for advancing the basic research needed to support the emergence of genome-guided precision medicine. Recent enhancements to MGD include new graphical summaries of biological annotations for mouse genes, support for mobile access to the database, tools to support the annotation and analysis of sets of genes, and expanded support for comparative biology through the expansion of homology data. PMID:26578600

  3. Data Extraction and Management in Networks of Observational Health Care Databases for Scientific Research: A Comparison of EU-ADR, OMOP, Mini-Sentinel and MATRICE Strategies

    PubMed Central

    Gini, Rosa; Schuemie, Martijn; Brown, Jeffrey; Ryan, Patrick; Vacchi, Edoardo; Coppola, Massimo; Cazzola, Walter; Coloma, Preciosa; Berni, Roberto; Diallo, Gayo; Oliveira, José Luis; Avillach, Paul; Trifirò, Gianluca; Rijnbeek, Peter; Bellentani, Mariadonata; van Der Lei, Johan; Klazinga, Niek; Sturkenboom, Miriam

    2016-01-01

    Introduction: We see increased use of existing observational data in order to achieve fast and transparent production of empirical evidence in health care research. Multiple databases are often used to increase power, to assess rare exposures or outcomes, or to study diverse populations. For privacy and sociological reasons, original data on individual subjects can’t be shared, requiring a distributed network approach where data processing is performed prior to data sharing. Case Descriptions and Variation Among Sites: We created a conceptual framework distinguishing three steps in local data processing: (1) data reorganization into a data structure common across the network; (2) derivation of study variables not present in original data; and (3) application of study design to transform longitudinal data into aggregated data sets for statistical analysis. We applied this framework to four case studies to identify similarities and differences in the United States and Europe: Exploring and Understanding Adverse Drug Reactions by Integrative Mining of Clinical Records and Biomedical Knowledge (EU-ADR), Observational Medical Outcomes Partnership (OMOP), the Food and Drug Administration’s (FDA’s) Mini-Sentinel, and the Italian network—the Integration of Content Management Information on the Territory of Patients with Complex Diseases or with Chronic Conditions (MATRICE). Findings: National networks (OMOP, Mini-Sentinel, MATRICE) all adopted shared procedures for local data reorganization. The multinational EU-ADR network needed locally defined procedures to reorganize its heterogeneous data into a common structure. Derivation of new data elements was centrally defined in all networks but the procedure was not shared in EU-ADR. Application of study design was a common and shared procedure in all the case studies. Computer procedures were embodied in different programming languages, including SAS, R, SQL, Java, and C++. Conclusion: Using our conceptual framework we found several areas that would benefit from research to identify optimal standards for production of empirical knowledge from existing databases.an opportunity to advance evidence-based care management. In addition, formalized CM outcomes assessment methodologies will enable us to compare CM effectiveness across health delivery settings. PMID:27014709

  4. Using the reactome database.

    PubMed

    Haw, Robin; Stein, Lincoln

    2012-06-01

    There is considerable interest in the bioinformatics community in creating pathway databases. The Reactome project (a collaboration between the Ontario Institute for Cancer Research, Cold Spring Harbor Laboratory, New York University Medical Center, and the European Bioinformatics Institute) is one such pathway database and collects structured information on all the biological pathways and processes in the human. It is an expert-authored and peer-reviewed, curated collection of well-documented molecular reactions that span the gamut from simple intermediate metabolism to signaling pathways and complex cellular events. This information is supplemented with likely orthologous molecular reactions in mouse, rat, zebrafish, worm, and other model organisms. This unit describes how to use the Reactome database to learn the steps of a biological pathway; navigate and browse through the Reactome database; identify the pathways in which a molecule of interest is involved; use the Pathway and Expression analysis tools to search the database for and visualize possible connections within user-supplied experimental data set and Reactome pathways; and the Species Comparison tool to compare human and model organism pathways. PMID:22700314

  5. Shuttle Hypervelocity Impact Database

    NASA Technical Reports Server (NTRS)

    Hyde, James L.; Christiansen, Eric L.; Lear, Dana M.

    2011-01-01

    With three missions outstanding, the Shuttle Hypervelocity Impact Database has nearly 3000 entries. The data is divided into tables for crew module windows, payload bay door radiators and thermal protection system regions, with window impacts compromising just over half the records. In general, the database provides dimensions of hypervelocity impact damage, a component level location (i.e., window number or radiator panel number) and the orbiter mission when the impact occurred. Additional detail on the type of particle that produced the damage site is provided when sampling data and definitive analysis results are available. Details and insights on the contents of the database including examples of descriptive statistics will be provided. Post flight impact damage inspection and sampling techniques that were employed during the different observation campaigns will also be discussed. Potential enhancements to the database structure and availability of the data for other researchers will be addressed in the Future Work section. A related database of returned surfaces from the International Space Station will also be introduced.

  6. Shuttle Hypervelocity Impact Database

    NASA Technical Reports Server (NTRS)

    Hyde, James I.; Christiansen, Eric I.; Lear, Dana M.

    2011-01-01

    With three flights remaining on the manifest, the shuttle impact hypervelocity database has over 2800 entries. The data is currently divided into tables for crew module windows, payload bay door radiators and thermal protection system regions, with window impacts compromising just over half the records. In general, the database provides dimensions of hypervelocity impact damage, a component level location (i.e., window number or radiator panel number) and the orbiter mission when the impact occurred. Additional detail on the type of particle that produced the damage site is provided when sampling data and definitive analysis results are available. The paper will provide details and insights on the contents of the database including examples of descriptive statistics using the impact data. A discussion of post flight impact damage inspection and sampling techniques that were employed during the different observation campaigns will be presented. Future work to be discussed will be possible enhancements to the database structure and availability of the data for other researchers. A related database of ISS returned surfaces that are under development will also be introduced.

  7. Using the Reactome Database

    PubMed Central

    Haw, Robin

    2012-01-01

    There is considerable interest in the bioinformatics community in creating pathway databases. The Reactome project (a collaboration between the Ontario Institute for Cancer Research, Cold Spring Harbor Laboratory, New York University Medical Center and the European Bioinformatics Institute) is one such pathway database and collects structured information on all the biological pathways and processes in the human. It is an expert-authored and peer-reviewed, curated collection of well-documented molecular reactions that span the gamut from simple intermediate metabolism to signaling pathways and complex cellular events. This information is supplemented with likely orthologous molecular reactions in mouse, rat, zebrafish, worm and other model organisms. This unit describes how to use the Reactome database to learn the steps of a biological pathway; navigate and browse through the Reactome database; identify the pathways in which a molecule of interest is involved; use the Pathway and Expression analysis tools to search the database for and visualize possible connections within user-supplied experimental data set and Reactome pathways; and the Species Comparison tool to compare human and model organism pathways. PMID:22700314

  8. Genetic predisposition to non-union: evidence today.

    PubMed

    Dimitriou, R; Kanakaris, N; Soucacos, P N; Giannoudis, P V

    2013-01-01

    Atrophic non-union represents a complex clinical condition and research is ongoing in an effort to elucidate its pathophysiology and to offer new and more efficient treatment modalities. Differences seen in fracture healing responses and final outcome may be attributed among other factors to biological variations between patients resulting in a "disturbed" signalling pathway and an "inert or deficient local biology with reduced potentials for bone regeneration". The genetic contribution with or without the interaction of other exogenous factors in cases of impaired fracture healing, is yet to be elucidated. However, preliminary animal and human studies demonstrate the molecular basis of fracture non-unions and correlate genetic variants of the molecules regulating fracture healing and their expression patterns with impaired bone healing and fracture non-union. Further research is needed to clarify the genetic component and its role and interaction with other risk factors that may result in increased susceptibility of a patient to develop this complication. PMID:23351872

  9. A Writer's Union for Academics?

    ERIC Educational Resources Information Center

    Aronowitz, Stanley

    1988-01-01

    Academics give away their written work without compensation and do not require a voice in determining the conditions under which their scholarship is published and disseminated. Joining forces with a writer's union would help bring equity to the publishing industry, faculty benefit, and fellow writers' benefit. (MSE)

  10. "Parent Unions" Join Policy Debates

    ERIC Educational Resources Information Center

    Cavanagh, Sean

    2012-01-01

    Whether they're organizing events, buttonholing legislators, or simply trading ideas and information, a growing number of "parent unions" are attempting to stake out a place in policy debates over education in states and districts, amid a crowded field of actors and advocates. As the term implies, some of these organizations see themselves as…

  11. Unionization among College Faculty-1993.

    ERIC Educational Resources Information Center

    Annunziato, Frank R., Ed.

    1993-01-01

    This newsletter theme issue analyzes college faculty union organization activities during 1992. It notes an increase in the number of collective bargaining agents, as eight collective bargaining elections were won by the American Association of University Professors (AAUP), American Federation of Teachers (AFT), and National Education Association…

  12. Are Unions Good for Professors?

    ERIC Educational Resources Information Center

    Aronowitz, Stanley

    1998-01-01

    As in other industries, expansion of part-time work has profoundly affected salaries and working conditions of full-time faculty and staff at many colleges. If public higher education is to survive the influences of privatization, vocationalization, and downsizing, faculty unions, having established a place in the academy, must become more heavily…

  13. CME in the Soviet Union

    PubMed Central

    Clark, Marvin

    1978-01-01

    This article documents the system of continuing medical education in the Soviet Union, as seen through the eyes of a visiting Canadian physician. The information was not easily obtained, since the visit was fraught with administrative difficulties, but the experience was highly educational, giving particular insight into the advantages and disadvantages of an educational system which is totally government funded. PMID:21301547

  14. Positive fast sealing union connections

    NASA Technical Reports Server (NTRS)

    Kleber, C. M.

    1972-01-01

    Union connections are designed for connecting high pressure flexible hoses from gas storage manifolds to gas transport trailers. Connection uses O ring seals which can be quickly assembled and disassembled without use of wrenches, and which do not twist hose. Worn or damaged O rings are easily replaced.

  15. Beyond Unions and Collective Bargaining.

    ERIC Educational Resources Information Center

    Troy, Leo

    2000-01-01

    Analyzes the reasons for decline of union representation to 9% of private sector workers. Suggests that workplace conditions and labor legislation designed to foster collective voice also sustain the individual system of representation, which is consistent with the philosophy of an open society. (SK)

  16. Risk of Mortality (including Sudden Cardiac Death) and Major Cardiovascular Events in Users of Olanzapine and Other Antipsychotics: A Study with the General Practice Research Database

    PubMed Central

    Jones, Meghan E.; Campbell, Giedra; Patel, Deven; Brunner, Elizabeth; Shatapathy, Chetan C.; Murray-Thomas, Tarita; van Staa, Tjeerd P.; Motsko, Stephen

    2013-01-01

    Objective. Assess risk of cardiac events and mortality among users of olanzapine and other antipsychotics relative to nonusers. Methods. The General Practice Research Database was used to identify cohorts of antipsychotic users and nonusers with psychiatric illness. Outcomes included cardiac mortality, sudden cardiac death (SCD), all-cause mortality (excluding suicide), coronary heart disease (CHD), and ventricular arrhythmias (VA). Results. 183,392 antipsychotic users (including 20,954 olanzapine users) and 193,920 psychiatric nonusers were identified. There was a significantly higher rate of cardiac mortality (adjusted RR [aRR]: 1.53, CI, 1.12–2.09) in olanzapine users relative to psychiatric nonusers, consistent with findings for both atypical and typical antipsychotics. Relative to psychiatric nonusers, no increased risk of all-cause mortality was observed among olanzapine users (aRR: 1.04, CI, 0.93–1.17), but elevated all-cause mortality risk was observed when compared to all antipsychotic users (aRR: 1.75, CI, 1.64–1.87). There was no increased risk of CHD or VA among olanzapine users relative to psychiatric nonusers, consistent with findings for atypical but not typical antipsychotics. SCD cases were uncommon. Conclusions. Use of antipsychotic agents was associated with increased risk of all-cause and cardiac mortality. Patients treated with olanzapine were found to be at increased risk of cardiac mortality versus psychiatric nonusers. PMID:24416588

  17. Pseudogene.org: a comprehensive database and comparison platform for pseudogene annotation

    PubMed Central

    Karro, John E.; Yan, Yangpan; Zheng, Deyou; Zhang, Zhaolei; Carriero, Nicholas; Cayting, Philip; Harrrison, Paul; Gerstein, Mark

    2007-01-01

    The Pseudogene.org knowledgebase serves as a comprehensive repository for pseudogene annotation. The definition of a pseudogene varies within the literature, resulting in significantly different approaches to the problem of identification. Consequently, it is difficult to maintain a consistent collection of pseudogenes in detail necessary for their effective use. Our database is designed to address this issue. It integrates a variety of heterogeneous resources and supports a subset structure that highlights specific groups of pseudogenes that are of interest to the research community. Tools are provided for the comparison of sets and the creation of layered set unions, enabling researchers to derive a current ‘consensus’ set of pseudogenes. Additional features include versatile search, the capacity for robust interaction with other databases, the ability to reconstruct older versions of the database (accounting for changing genome builds) and an underlying object-oriented interface designed for researchers with a minimal knowledge of programming. At the present time, the database contains more than 100?000 pseudogenes spanning 64 prokaryote and 11 eukaryote genomes, including a collection of human annotations compiled from 16 sources. PMID:17099229

  18. Pseudogene.org: a comprehensive database and comparison platform for pseudogene annotation.

    PubMed

    Karro, John E; Yan, Yangpan; Zheng, Deyou; Zhang, Zhaolei; Carriero, Nicholas; Cayting, Philip; Harrrison, Paul; Gerstein, Mark

    2007-01-01

    The Pseudogene.org knowledgebase serves as a comprehensive repository for pseudogene annotation. The definition of a pseudogene varies within the literature, resulting in significantly different approaches to the problem of identification. Consequently, it is difficult to maintain a consistent collection of pseudogenes in detail necessary for their effective use. Our database is designed to address this issue. It integrates a variety of heterogeneous resources and supports a subset structure that highlights specific groups of pseudogenes that are of interest to the research community. Tools are provided for the comparison of sets and the creation of layered set unions, enabling researchers to derive a current 'consensus' set of pseudogenes. Additional features include versatile search, the capacity for robust interaction with other databases, the ability to reconstruct older versions of the database (accounting for changing genome builds) and an underlying object-oriented interface designed for researchers with a minimal knowledge of programming. At the present time, the database contains more than 100,000 pseudogenes spanning 64 prokaryote and 11 eukaryote genomes, including a collection of human annotations compiled from 16 sources. PMID:17099229

  19. Construction of a Geographical Database of Classical-Archaic Manufactures, Found in the Survey of the Greek Colony Himera (sicily, Italy). Application and Methodologies for AN Experimental Research

    NASA Astrophysics Data System (ADS)

    Papa, M. A.; Tardo, V.

    2011-09-01

    This research has analysed the distribution of ceramic finds from classical and archaic ages in the territory of the ancient Greek colony Himera, a town situated near Termini Imerese, in the province of Palermo (Sicily, Italy), which has been the site of systematic excavations carried out by the University of Palermo since the Sixties. The study of about 1500 ceramic fragments, dated back to the 6th-5th century B.C., has allowed to develop an approach to the understanding of the role played by ceramics in the relations between different societies and cultures. Besides the most common analysis factors for the ceramic manufactures, such as their production and distribution, a major factor is the way the manufactures were used. From this wider perspective, a new methodology has been developed about information potential of functional analysis. The interpretation of data about the manufacture distribution was made by means of GIS methodologies, querying the alphanumerical classification database and relating the manufacture typological data to the geo-cartographic ones by means of applying intersite-level spatial analysis. Thus, each archaeological piece of information about the finds can be analysed in relation to the territory geo-morphological features and the obtained data can be processed with specific software environments, in order to suggest reconstruction models for the anthropic landscape, based on the relation between coeval sites and distance from specific environment features — for example, distance from water sources, raw materials, road condition etc. The computer application used for data handling, presentation and analysis, becomes this way a tool of research aimed at the comprehension of settlement dynamics in the historical scenery. This study is the occasion to propose such an analysis system of cultural heritage as a new tool to promote it and to increase its value, applying a territorial context related methodology founded on scientific evidence.

  20. Proliferation and the former Soviet Union

    SciTech Connect

    Not Available

    1994-09-01

    The report examines the whole range of consequences for proliferation of weapons of mass destruction of the Soviet Union's breakup and describes how U.S. assistance may reduce specific proliferation risks in the former Soviet Union.

  1. Partnership Creates Centre for Union Studies

    ERIC Educational Resources Information Center

    Smart, Carol; Roman, Stephen

    1978-01-01

    A unique cooperative venture between the city of Coventry and local trade unions is establishing a library collection of books, periodicals, historical documents, tapes, and films dealing with unions, labor studies, and industrial problems. (JAB)

  2. The PubChemQC project: A large chemical database from the first principle calculations

    NASA Astrophysics Data System (ADS)

    Maho, Nakata

    2015-12-01

    In this research, we have been constructing a large database of molecules by ab initio calculations. Currently, we have over 1.53 million entries of 6-31G* B3LYP optimized geometries and ten excited states by 6-31+G* TDDFT calculations. To calculate molecules, we only refer the InChI (International Chemical Identifier) representation of chemical formula by the International Union of Pure and Applied Chemistry (IUPAC), thus, no reference to experimental data. These results are open to public at http://pubchemqc.riken.jp/. The molecular data have been taken from the PubChem Project (http://pubchem.ncbi.nlm.nih.gov/) which is one of the largest in the world (approximately 63 million molecules are listed) and free (public domain) database. Our final goal is, using these data, to develop a molecular search engine or molecular expert system to find molecules which have desired properties.

  3. Stackfile Database

    NASA Technical Reports Server (NTRS)

    deVarvalho, Robert; Desai, Shailen D.; Haines, Bruce J.; Kruizinga, Gerhard L.; Gilmer, Christopher

    2013-01-01

    This software provides storage retrieval and analysis functionality for managing satellite altimetry data. It improves the efficiency and analysis capabilities of existing database software with improved flexibility and documentation. It offers flexibility in the type of data that can be stored. There is efficient retrieval either across the spatial domain or the time domain. Built-in analysis tools are provided for frequently performed altimetry tasks. This software package is used for storing and manipulating satellite measurement data. It was developed with a focus on handling the requirements of repeat-track altimetry missions such as Topex and Jason. It was, however, designed to work with a wide variety of satellite measurement data [e.g., Gravity Recovery And Climate Experiment -- GRACE). The software consists of several command-line tools for importing, retrieving, and analyzing satellite measurement data.

  4. JDD, Inc. Database

    NASA Technical Reports Server (NTRS)

    Miller, David A., Jr.

    2004-01-01

    JDD Inc, is a maintenance and custodial contracting company whose mission is to provide their clients in the private and government sectors "quality construction, construction management and cleaning services in the most efficient and cost effective manners, (JDD, Inc. Mission Statement)." This company provides facilities support for Fort Riley in Fo,rt Riley, Kansas and the NASA John H. Glenn Research Center at Lewis Field here in Cleveland, Ohio. JDD, Inc. is owned and operated by James Vaughn, who started as painter at NASA Glenn and has been working here for the past seventeen years. This summer I worked under Devan Anderson, who is the safety manager for JDD Inc. in the Logistics and Technical Information Division at Glenn Research Center The LTID provides all transportation, secretarial, security needs and contract management of these various services for the center. As a safety manager, my mentor provides Occupational Health and Safety Occupation (OSHA) compliance to all JDD, Inc. employees and handles all other issues (Environmental Protection Agency issues, workers compensation, safety and health training) involving to job safety. My summer assignment was not as considered "groundbreaking research" like many other summer interns have done in the past, but it is just as important and beneficial to JDD, Inc. I initially created a database using a Microsoft Excel program to classify and categorize data pertaining to numerous safety training certification courses instructed by our safety manager during the course of the fiscal year. This early portion of the database consisted of only data (training field index, employees who were present at these training courses and who was absent) from the training certification courses. Once I completed this phase of the database, I decided to expand the database and add as many dimensions to it as possible. Throughout the last seven weeks, I have been compiling more data from day to day operations and been adding the information to the database. It now consists of seven different categories of data (carpet cleaning, forms, NASA Event Schedules, training certifications, wall and vent cleaning, work schedules, and miscellaneous) . I also did some field inspecting with the supervisors around the site and was present at all of the training certification courses that have been scheduled since June 2004. My future outlook for the JDD, Inc. database is to have all of company s information from future contract proposals, weekly inventory, to employee timesheets all in this same database.

  5. The AMMA database

    NASA Astrophysics Data System (ADS)

    Boichard, Jean-Luc; Brissebrat, Guillaume; Cloche, Sophie; Eymard, Laurence; Fleury, Laurence; Mastrorillo, Laurence; Moulaye, Oumarou; Ramage, Karim

    2010-05-01

    The AMMA project includes aircraft, ground-based and ocean measurements, an intensive use of satellite data and diverse modelling studies. Therefore, the AMMA database aims at storing a great amount and a large variety of data, and at providing the data as rapidly and safely as possible to the AMMA research community. In order to stimulate the exchange of information and collaboration between researchers from different disciplines or using different tools, the database provides a detailed description of the products and uses standardized formats. The AMMA database contains: - AMMA field campaigns datasets; - historical data in West Africa from 1850 (operational networks and previous scientific programs); - satellite products from past and future satellites, (re-)mapped on a regular latitude/longitude grid and stored in NetCDF format (CF Convention); - model outputs from atmosphere or ocean operational (re-)analysis and forecasts, and from research simulations. The outputs are processed as the satellite products are. Before accessing the data, any user has to sign the AMMA data and publication policy. This chart only covers the use of data in the framework of scientific objectives and categorically excludes the redistribution of data to third parties and the usage for commercial applications. Some collaboration between data producers and users, and the mention of the AMMA project in any publication is also required. The AMMA database and the associated on-line tools have been fully developed and are managed by two teams in France (IPSL Database Centre, Paris and OMP, Toulouse). Users can access data of both data centres using an unique web portal. This website is composed of different modules : - Registration: forms to register, read and sign the data use chart when an user visits for the first time - Data access interface: friendly tool allowing to build a data extraction request by selecting various criteria like location, time, parameters... The request can concern local, satellite and model data. - Documentation: catalogue of all the available data and their metadata. These tools have been developed using standard and free languages and softwares: - Linux system with an Apache web server and a Tomcat application server; - J2EE tools : JSF and Struts frameworks, hibernate; - relational database management systems: PostgreSQL and MySQL; - OpenLDAP directory. In order to facilitate the access to the data by African scientists, the complete system has been mirrored at AGHRYMET Regional Centre in Niamey and is operational there since January 2009. Users can now access metadata and request data through one or the other of two equivalent portals: http://database.amma-international.org or http://amma.agrhymet.ne/amma-data.

  6. Justice Perceptions of Union and Nonunion Employees within an Urban Technical College

    ERIC Educational Resources Information Center

    Vasquez, Marquoise D.

    2013-01-01

    Numerous studies exist on distributive and procedural justice among union represented or nonunion employees. However, there does not appear to be any research on the perceptions of justice from individuals who have worked in both capacities, under differing processes and procedures for each group, within the same heavily unionized organization.…

  7. Education for Organising in a Hot Climate: A Manufacturing Union's Experience

    ERIC Educational Resources Information Center

    Brown, Tony

    2006-01-01

    This paper reports on research into a national education program within one of Australia's largest trade unions. The program was designed to assist the union's staff and elected officials respond to the rapidly changing industrial and political conditions in the manufacturing sector. It is ambitious in scope comprising sixteen modules that range…

  8. Justice Perceptions of Union and Nonunion Employees within an Urban Technical College

    ERIC Educational Resources Information Center

    Vasquez, Marquoise D.

    2013-01-01

    Numerous studies exist on distributive and procedural justice among union represented or nonunion employees. However, there does not appear to be any research on the perceptions of justice from individuals who have worked in both capacities, under differing processes and procedures for each group, within the same heavily unionized organization.…

  9. ETUDE - European Trade Union Distance Education.

    ERIC Educational Resources Information Center

    Creanor, Linda; Walker, Steve

    2000-01-01

    Describes transnational distance learning activities among European trade union educators carried out as part of the European Trade Union Distance Education (ETUDE) project, supported by the European Commission. Highlights include the context of international trade union distance education; tutor training course; tutors' experiences; and…

  10. ETUDE - European Trade Union Distance Education.

    ERIC Educational Resources Information Center

    Creanor, Linda; Walker, Steve

    2000-01-01

    Describes transnational distance learning activities among European trade union educators carried out as part of the European Trade Union Distance Education (ETUDE) project, supported by the European Commission. Highlights include the context of international trade union distance education; tutor training course; tutors' experiences; and…

  11. A Different Role for Teachers Unions

    ERIC Educational Resources Information Center

    Tucker, Marc

    2012-01-01

    American teachers unions are increasingly the target of measures, authored by friends and foes alike, intended to limit their power, or even eviscerate them. Looking at this scene, one would never guess that the countries that are among the top 10 in student performance have some of the strongest teachers unions in the world. Are those unions in…

  12. 78 FR 72537 - Credit Union Service Organizations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-03

    ... union system to require CUSOs to submit information about their financial condition directly to NCUA... mitigating risk to the credit union system as a whole. It emphasizes that NCUA intends to use the information... federally insured, state-chartered credit unions (FISCUs) to address accounting, financial statements,...

  13. Teacher Union Contracts and High School Reform

    ERIC Educational Resources Information Center

    Price, Mitch

    2009-01-01

    Are teachers unions and collective bargaining agreements barriers to high school reform and redesign efforts in Washington, California, and Ohio? The short answer: sometimes, but not as often as many educators seem to think. Rather than wade into the pro- versus anti-union debate, this report instead aims to offer guidance for educators, unions,…

  14. Are Charter School Unions Worth the Bargain?

    ERIC Educational Resources Information Center

    Price, Mitch

    2011-01-01

    About 12 percent of all charter schools have bargaining agreements. Why do charter schools unionize? What is in these charter school contracts? Can they be considered innovative or models for union reform? And how do they compare to traditional district/union teacher contracts? Center on Reinventing Public Education legal analyst Mitch Price…

  15. Unions and Job Satisfaction: An Alternative View.

    ERIC Educational Resources Information Center

    Pfeffer, Jeffrey; Davis-Blake, Alison

    1990-01-01

    The dominant theoretical perspective suggests that unions reduce job satisfaction by making workers more critical of the workplace and more willing to complain. However, unions reduce wage inequality and increase worker control and commitment. A survey of 978 workers shows that unionization has a positive effect on job satisfaction. (JOW)

  16. Manufacturing Dissent: Labor Revitalization, Union Summer and Student Protest

    ERIC Educational Resources Information Center

    Van Dyke, Nella; Dixon, Marc; Carlon, Helen

    2007-01-01

    During the late 1990s, college students across the United States mobilized around labor issues. Our research explores whether this explosion of student protest activity was generated, in part, by concerted efforts of the AFL-CIO through its Union Summer college student internship program. A statistical analysis of factors influencing the location…

  17. Manufacturing Dissent: Labor Revitalization, Union Summer and Student Protest

    ERIC Educational Resources Information Center

    Van Dyke, Nella; Dixon, Marc; Carlon, Helen

    2007-01-01

    During the late 1990s, college students across the United States mobilized around labor issues. Our research explores whether this explosion of student protest activity was generated, in part, by concerted efforts of the AFL-CIO through its Union Summer college student internship program. A statistical analysis of factors influencing the location…

  18. Attitude Change of American Tourists in the Soviet Union.

    ERIC Educational Resources Information Center

    Grothe, Peter

    Pre- and post-travel questionnaires mailed to American tourists visiting the Soviet Union record attitude change and serve as the basis for this eight-chapter research project report. Most of the report considers the relation of various factors to attitude change, including education, level of information, language ability, sex, age, occupation,…

  19. Earthquake and Landslides in the Union of the Comoros

    USGS Multimedia Gallery

    Heavy rains from a tropical cyclone struck the islands of the Comoros in March, 2014. On the island of Anjouan in the Union of Comoros, these rains triggered landslides that displaced over 3000 people to refugee camps. The USGS and the OFDA with USAID are providing support and research assistance on...

  20. CIRRIE DATABASE

    EPA Science Inventory

    International rehabilitation research published between 1990 and the present. Over 18,000 citations. In addition to indexing from mainstream journals and Internet sites, CIRRIE also includes citations to resources not readily available to U.S. researchers. There are over 18,000 c...